                         SEQUENCE LISTING

<110>  CureVac AG
 
<120>  Novel RSV RNA molecules and compositions for vaccination

<130>  CU01P281WO1

<160>  21706 

<170>  PatentIn version 3.5

<210>  1
<211>  62
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human peroxisomal multifunctional enzyme type 2 lacking
       the 5'-terminal oligopyrimidine tract (HSD17B4)

<400>  1
gtcccgcagt cggcgtccag cggctctgct tgttcgtgtg tgtgtcgttg caggccttat       60

tc                                                                      62


<210>  2
<211>  62
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human peroxisomal multifunctional enzyme type 2 lacking
       the 5'-terminal oligopyrimidine tract (HSD17B4) mRNA

<400>  2
gucccgcagu cggcguccag cggcucugcu uguucgugug ugugucguug caggccuuau       60

uc                                                                      62


<210>  3
<211>  42
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human acid ceramidase lacking the 5'-terminal 
       oligopyrimidine tract (ASAH1)

<400>  3
gcctctgctg gagtccgggg agtggcgttg gctgctagag cg                          42


<210>  4
<211>  42
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human acid ceramidase lacking the 5'-terminal 
       oligopyrimidine tract (ASAH1) mRNA

<400>  4
gccucugcug gaguccgggg aguggcguug gcugcuagag cg                          42


<210>  5
<211>  75
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human mitochondrial ATP synthase subunit alpha lacking 
       the 5'-terminal oligopyrimidine tract (ATP5A1)

<400>  5
gcggctcggc cattttgtcc cagtcagtcc ggaggctgcg gctgcagaag taccgcctgc       60

ggagtaactg caaag                                                        75


<210>  6
<211>  75
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human mitochondrial ATP synthase subunit alpha lacking 
       the 5'-terminal oligopyrimidine tract (ATP5A1) mRNA

<400>  6
gcggcucggc cauuuugucc cagucagucc ggaggcugcg gcugcagaag uaccgccugc       60

ggaguaacug caaag                                                        75


<210>  7
<211>  54
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse RIKEN cDNA 2010107E04 gene (Mp68, 2010107E04Rik)

<400>  7
ctttcccatt ctgtagcaga atttggtgtt gcctgtggtc ttggtcccgc ggag             54


<210>  8
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse RIKEN cDNA 2010107E04 gene (Mp68, 2010107E04Rik) 
       mRNA

<400>  8
cuuucccauu cuguagcaga auuugguguu gccugugguc uuggucccgc ggag             54


<210>  9
<211>  81
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse NADH dehydrogenase (ubiquinone) 1 alpha 
       subcomplex, 4 (Ndufa4)

<400>  9
gtccgctcag ccaggttgca gaagcggctt agcgtgtgtc ctaatcttct ctctgcgtgt       60

aggtaggcct gtgccgcaaa c                                                 81


<210>  10
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse NADH dehydrogenase (ubiquinone) 1 alpha 
       subcomplex, 4 (Ndufa4) mRNA

<400>  10
guccgcucag ccagguugca gaagcggcuu agcguguguc cuaaucuucu cucugcgugu       60

agguaggccu gugccgcaaa c                                                 81


<210>  11
<211>  108
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse nitric oxide synthase interacting protein (Nosip)

<400>  11
ctcctgtcgg gcggaagtag gaggagtaga gtttaaaaac agtactcttt ttccggttcg       60

ggacgtagtt gaagcaacga caagccggat aaccgctctt gagacagg                   108


<210>  12
<211>  108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse nitric oxide synthase interacting protein (Nosip)
       mRNA

<400>  12
cuccugucgg gcggaaguag gaggaguaga guuuaaaaac aguacucuuu uuccgguucg       60

ggacguaguu gaagcaacga caagccggau aaccgcucuu gagacagg                   108


<210>  13
<211>  84
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse ribosomal protein L31 (Rpl31)

<400>  13
cccgtgaccc ggaagttgta cggctacgcg actttccctc ccacaaaccc tcgcgccctt       60

cctttcctac ttgggcccgg caga                                              84


<210>  14
<211>  84
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse ribosomal protein L31 (Rpl31) mRNA

<400>  14
cccgugaccc ggaaguugua cggcuacgcg acuuucccuc ccacaaaccc ucgcgcccuu       60

ccuuuccuac uugggcccgg caga                                              84


<210>  15
<211>  159
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse solute carrier family 7 (cationic amino acid 
       transporter, y+ system), member 3 (Slc7a3)

<400>  15
gggcgcttgg cttgcaagga ccctgagctg cggcattgaa gcacacccaa cccaactcga       60

ctgaagtcag cctcactgaa ccggatctga gaatcttctc tctctgggct tgccagggct      120

ctccgaacct agctagcatc ctcttcaatt ccaactaga                             159


<210>  16
<211>  159
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse solute carrier family 7 (cationic amino acid 
       transporter, y+ system), member 3 (Slc7a3) mRNA

<400>  16
gggcgcuugg cuugcaagga cccugagcug cggcauugaa gcacacccaa cccaacucga       60

cugaagucag ccucacugaa ccggaucuga gaaucuucuc ucucugggcu ugccagggcu      120

cuccgaaccu agcuagcauc cucuucaauu ccaacuaga                             159


<210>  17
<211>  102
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human tubulin beta 4B class Ivb (TUBB4B)

<400>  17
atataagcgt tggcggagcg tcggttgtag cactctgcgc gcccgctctt ctgctgctgt       60

ttgtctactt cctcctgctt ccccgccgcc gccgccgcca tc                         102


<210>  18
<211>  102
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human tubulin beta 4B class Ivb (TUBB4B) mRNA

<400>  18
auauaagcgu uggcggagcg ucgguuguag cacucugcgc gcccgcucuu cugcugcugu       60

uugucuacuu ccuccugcuu ccccgccgcc gccgccgcca uc                         102


<210>  19
<211>  222
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse ubiquilin 2 (Ubqln2)

<400>  19
cggagacggc ctgcaggacc tgctctctca gccctcagcc gaggcctacg ccgagccgag       60

tgcgcagccg acgaccggga ggagccgcag ccttcaactc tgaggtactg tgatccgcgc      120

tgcccgccgg gccgccccag tccgctgctg cggcacctcc ttccctcgcg ccctcttcgc      180

tcgccagcgc cttccctgtg agcctgcgtc accgcggccg cc                         222


<210>  20
<211>  222
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of mouse ubiquilin 2 (Ubqln2)  mRNA

<400>  20
cggagacggc cugcaggacc ugcucucuca gcccucagcc gaggccuacg ccgagccgag       60

ugcgcagccg acgaccggga ggagccgcag ccuucaacuc ugagguacug ugauccgcgc      120

ugcccgccgg gccgccccag uccgcugcug cggcaccucc uucccucgcg cccucuucgc      180

ucgccagcgc cuucccugug agccugcguc accgcggccg cc                         222


<210>  21
<211>  42
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human ribosomal protein Large 32 lacking the 
       5'-terminal oligopyrimidine tract (RPL32, 32L4)

<400>  21
ggcgctgcct acggaggtgg cagccatctc cttctcggca tc                          42


<210>  22
<211>  42
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5'-UTR of human ribosomal protein Large 32 lacking the 
       5'-terminal oligopyrimidine tract (RPL32, 32L4) mRNA

<400>  22
ggcgcugccu acggaggugg cagccaucuc cuucucggca uc                          42


<210>  23
<211>  57
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human proteasome subunit beta 3 (PSMB3)

<400>  23
ccctgttccc agagcccact tttttttctt tttttgaaat aaaatagcct gtctttc          57


<210>  24
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human proteasome subunit beta 3 (PSMB3) mRNA

<400>  24
cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuuc          57


<210>  25
<211>  121
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human caspase 1 (CASP1)

<400>  25
aataaggaaa ctgtatgaat gtctgtgggc aggaagtgaa gagatccttc tgtaaaggtt       60

tttggaatta tgtctgctga ataataaact tttttgaaat aataaatctg gtagaaaaat      120

g                                                                      121


<210>  26
<211>  121
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human caspase 1 (CASP1) mRNA

<400>  26
aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu       60

uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau      120

g                                                                      121


<210>  27
<211>  137
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human cytochrome c oxidase subunit 6B1 (COX6B1)

<400>  27
actggctgca tctccctttc ctctgtcctc catccttctc ccaggatggt gaagggggac       60

ctggtaccca gtgatcccca ccccaggatc ctaaatcatg acttacctgc taataaaaac      120

tcattggaaa agtgaga                                                     137


<210>  28
<211>  137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human cytochrome c oxidase subunit 6B1 (COX6B1) mRNA

<400>  28
acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac       60

cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac      120

ucauuggaaa agugaga                                                     137


<210>  29
<211>  353
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of mouse GNAS (guanine nucleotide binding protein, alpha 
       stimulating) complex locus (Gnas)

<400>  29
gaagggaaca cccaaattta attcagcctt aagcacaatt aattaagagt gaaacgtaat       60

tgtacaagca gttggtcacc caccataggg catgatcaac accgcaacct ttcctttttc      120

ccccagtgat tctgaaaaac ccctcttccc ttcagcttgc ttagatgttc caaatttagt      180

aagcttaagg cggcctacag aagaaaaaga aaaaaaaggc cacaaaagtt ccctctcact      240

ttcagtaaat aaaataaaag cagcaacaga aataaagaaa taaatgaaat tcaaaatgaa      300

ataaatattg tgttgtgcag cattaaaaaa tcaataaaaa ttaaaaatga gca             353


<210>  30
<211>  353
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of mouse GNAS (guanine nucleotide binding protein, alpha 
       stimulating) complex locus (Gnas) mRNA

<400>  30
gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau       60

uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc      120

ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu      180

aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu      240

uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa      300

auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gca             353


<210>  31
<211>  133
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of mouse NADH dehydrogenase (ubiquinone) 1 alpha 
       subcomplex, 1 (Ndufa1)

<400>  31
ggaagcattt tcctggctga ttaaaagaaa ttactcagct atggtcatct gttcctgtta       60

gaaggctatg cagcatatta tatactatgc gcatgttatg aaatgcataa taaaaaattt      120

taaaaaatct aaa                                                         133


<210>  32
<211>  133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of mouse NADH dehydrogenase (ubiquinone) 1 alpha 
       subcomplex, 1 (Ndufa1) mRNA

<400>  32
ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua       60

gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu      120

uaaaaaaucu aaa                                                         133


<210>  33
<211>  70
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human ribosomal protein S9 (RPS9)

<400>  33
gtccacctgt ccctcctggg ctgctggatt gtctcgtttt cctgccaaat aaacaggatc       60

agcgctttac                                                              70


<210>  34
<211>  70
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human ribosomal protein S9 (RPS9) mRNA

<400>  34
guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc       60

agcgcuuuac                                                              70


<210>  35
<211>  187
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR ALB7

<400>  35
gcatcacatt taaaagcatc tcagcctacc atgagaataa gagaaagaaa atgaagatca       60

atagcttatt catctctttt tctttttcgt tggtgtaaag ccaacaccct gtctaaaaaa      120

cataaatttc tttaatcatt ttgcctcttt tctctgtgct tcaattaata aaaaatggaa      180

agaacct                                                                187


<210>  36
<211>  187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR ALB7 mRNA

<400>  36
gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca       60

auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa      120

cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa      180

agaaccu                                                                187


<210>  37
<211>  44
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Center, alpha-complex-binding portion of the 3'-UTR of an 
       alpha-globin gene (muag)

<400>  37
gcccgatggg cctcccaacg ggccctcctc ccctccttgc accg                        44


<210>  38
<211>  44
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Center, alpha-complex-binding portion of the 3'-UTR of an 
       alpha-globin gene (muag) mRNA

<400>  38
gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accg                        44


<210>  39
<211>  24
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  histone stem-loop sequence (histoneSL, hSL)

<400>  39
caaaggctct tttcagagcc acca                                              24


<210>  40
<211>  24
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  histone stem-loop sequence (histoneSL, hSL) mRNA

<400>  40
caaaggcucu uuucagagcc acca                                              24


<210>  41
<211>  13
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Kozak

<400>  41
gccgccacca tgg                                                          13


<210>  42
<211>  13
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Kozak mRNA

<400>  42
gccgccacca ugg                                                          13


<210>  43
<211>  6
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 5'-end

<400>  43
gggaga                                                                   6


<210>  44
<211>  99
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end A75-histoneSL

<400>  44
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaacaaag gcucuuuuca gagccacca                              99


<210>  45
<211>  102
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end U3-A75-histoneSL

<400>  45
uuuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaaaca aaggcucuuu ucagagccac ca                         102


<210>  46
<211>  178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end A154-histoneSL

<400>  46
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaacaaagg cucuuuucag agccacca        178


<210>  47
<211>  181
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end U3-A154-histoneSL

<400>  47
uuuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaacaa aggcucuuuu cagagccacc      180

a                                                                      181


<210>  48
<211>  101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N2-A75-histoneSL

<400>  48
agaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaacaa aggcucuuuu cagagccacc a                          101


<210>  49
<211>  99
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end histoneSL-A75

<400>  49
caaaggcucu uuucagagcc accaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                              99


<210>  50
<211>  124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end histoneSL-A100

<400>  50
caaaggcucu uuucagagcc accaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      120

aaaa                                                                   124


<210>  51
<211>  170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end histoneSL-A146

<400>  51
caaaggcucu uuucagagcc accaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                 170


<210>  52
<211>  136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N8-A64-N5-C30-histoneSL-N5

<400>  52
agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      120

cagagccacc agaauu                                                      136


<210>  53
<211>  131
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N8-A64-N5-C30-histoneSL

<400>  53
agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      120

cagagccacc a                                                           131


<210>  54
<211>  105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N8-A64-N5-C4-histoneSL

<400>  54
agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaugcauccc ccaaaggcuc uuuucagagc cacca                      105


<210>  55
<211>  115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N8-A64-N5-C14-histoneSL

<400>  55
agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaugcauccc cccccccccc ccaaaggcuc uuuucagagc cacca           115


<210>  56
<211>  134
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N6-A64-N5-C30-histoneSL-N5

<400>  56
agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca      120

gagccaccag aauu                                                        134


<210>  57
<211>  129
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N6-A64-N5-C30-histoneSL

<400>  57
agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca      120

gagccacca                                                              129


<210>  58
<211>  103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N6-A64-N5-C4-histoneSL

<400>  58
agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa ugcauccccc aaaggcucuu uucagagcca cca                        103


<210>  59
<211>  113
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end N6-A64-N5-C14-histoneSL

<400>  59
agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa ugcauccccc cccccccccc aaaggcucuu uucagagcca cca             113


<210>  60
<211>  128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end A64-N5-C30-histoneSL-N5

<400>  60
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca      120

ccagaauu                                                               128


<210>  61
<211>  123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end A64-N5-C30-histoneSL

<400>  61
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca      120

cca                                                                    123


<210>  62
<211>  97
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end A64-N5-C4-histoneSL

<400>  62
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaugcauc ccccaaaggc ucuuuucaga gccacca                                97


<210>  63
<211>  107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA 3'-end A64-N5-C14-histoneSL

<400>  63
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa       60

aaaaugcauc cccccccccc ccccaaaggc ucuuuucaga gccacca                    107


<210>  64
<211>  14
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       Artificial__carrier peptide 1

<400>  64

Cys Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Cys 
1               5                   10                  


<210>  65
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       Artificial__carrier peptide 2

<400>  65

Cys Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg 
1               5                   10              


<210>  66
<211>  14
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       Artificial__carrier peptide 3

<400>  66

Trp Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Cys 
1               5                   10                  


<210>  67
<211>  18
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       Artificial__carrier peptide 4

<400>  67

Cys His His His His His His Arg Arg Arg Arg His His His His His 
1               5                   10                  15      


His Cys 
        


<210>  68
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F0

<400>  68

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  69
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (artificial) from 
       HRSV(A2)__F0

<400>  69
auggaguugc uaauccucaa agcaaaugca auuaccacaa uccucacugc agucacauuu       60

uguuuugcuu cuggucaaaa caucacugaa gaauuuuauc aaucaacaug cagugcaguu      120

agcaaaggcu aucuuagugc ucugagaacu gguugguaua ccaguguuau aacuauagaa      180

uuaaguaaua ucaaggaaaa uaaguguaau ggaacagaug cuaagguaaa auugauaaaa      240

caagaauuag auaaauauaa aaaugcugua acagaauugc aguugcucau gcaaagcaca      300

ccagcaacaa acaaucgagc cagaagagaa cuaccaaggu uuaugaauua uacacucaac      360

aaugccaaaa aaaccaaugu aacauuaagc aagaaaagga aaagaagauu ucuugguuuu      420

uuguuaggug uuggaucugc aaucgccagu ggcguugcug uaucuaaggu ccugcaccua      480

gaaggggaag ugaacaagau caaaagugcu cuacuaucca caaacaaggc uguagucagc      540

uuaucaaaug gaguuagugu cuuaaccagc aaaguguuag accucaaaaa cuauauagau      600

aaacaauugu uaccuauugu gaacaagcaa agcugcagca uaucaaauau agaaacugug      660

auagaguucc aacaaaagaa caacagacua cuagagauua ccagggaauu uaguguuaau      720

gcagguguaa cuacaccugu aagcacuuac auguuaacua auagugaauu auugucauua      780

aucaaugaua ugccuauaac aaaugaucag aaaaaguuaa uguccaacaa uguucaaaua      840

guuagacagc aaaguuacuc uaucaugucc auaauaaaag aggaagucuu agcauaugua      900

guacaauuac cacuauaugg uguuauagau acacccuguu ggaaacuaca cacauccccu      960

cuauguacaa ccaacacaaa agaagggucc aacaucuguu uaacaagaac ugacagagga     1020

ugguacugug acaaugcagg aucaguaucu uucuucccac aagcugaaac auguaaaguu     1080

caaucaaauc gaguauuuug ugacacaaug aacaguuuaa cauuaccaag ugaaguaaau     1140

cucugcaaug uugacauauu caaccccaaa uaugauugua aaauuaugac uucaaaaaca     1200

gauguaagca gcuccguuau cacaucucua ggagccauug ugucaugcua uggcaaaacu     1260

aaauguacag cauccaauaa aaaucgugga aucauaaaga cauuuucuaa cgggugcgau     1320

uauguaucaa auaaaggggu ggacacugug ucuguaggua acacauuaua uuauguaaau     1380

aagcaagaag guaaaagucu cuauguaaaa ggugaaccaa uaauaaauuu cuaugaccca     1440

uuaguauucc ccucugauga auuugaugca ucaauaucuc aagucaacga gaagauuaac     1500

cagagccuag cauuuauucg uaaauccgau gaauuauuac auaauguaaa ugcugguaaa     1560

uccaccacaa auaucaugau aacuacuaua auuauaguga uuauaguaau auuguuauca     1620

uuaauugcug uuggacugcu cuuauacugu aaggccagaa gcacaccagu cacacuaagc     1680

aaagaucaac ugagugguau aaauaauauu gcauuuagua acuaa                     1725


<210>  70
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from HRSV(A2)__F0

<400>  70
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccaccug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacg ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaacca acaaccgcgc ccggcgcgag cugccccggu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgca agcggcgcuu ccugggcuuc      420

cuccuggggg ugggcuccgc caucgcgagc ggcgucgccg uguccaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccucc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccaucgu caacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugucc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acuga                     1725


<210>  71
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from HRSV(A2)__F0

<400>  71
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccacca acaaccgggc ccgccgggag cugccgcgcu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgga agcgccgguu ccugggcuuc      420

cuccuggggg ugggcuccgc gaucgccagc ggcgucgccg uguccaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccucc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccaucgu caacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccgccuc cuggagauca cccgggaguu cagcgugaac      720

gcggggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccgccagc aguccuacag caucaugucc aucaucaagg aggaggugcu ggccuacgug      900

guccagcugc cgcucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcggac cgaccgcggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaacc ggguguucug cgacaccaug aacucccuga cgcugccgag cgaggucaac     1140

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgucau caccucccug ggggccaucg ugagcugcua cggcaagacg     1260

aagugcaccg cgagcaacaa gaaccgcggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacaccgug uccgugggga acacccugua cuacgucaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cguccgacga guucgacgcc agcaucuccc aggucaacga gaagaucaac     1500

cagagccugg ccuucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguga ucaucgucau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcgcgca gcacgcccgu gacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gccuucucca acuga                     1725


<210>  72
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from HRSV(A2)__F0

<400>  72
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccacca acaaccgcgc ccgccgcgag cucccccgcu ucaugaacua cacccucaac      360

aacgccaaga agaccaacgu cacccucucc aagaagcgca agcgccgcuu ccucggcuuc      420

cuccucggcg ucggcuccgc caucgccucc ggcgucgccg ucuccaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccucc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccaucgu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugucc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acuga                     1725


<210>  73
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from HRSV(A2)__F0

<400>  73
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccacca acaauagggc ucggcgcgag uugccucgau uuaugaacua cacgcucaau      360

aacgcaaaga aaacuaaugu gacccugucg aagaaacgua agagaagguu ccugggcuuu      420

cucuuagggg ucggaucagc cauagcuagc ggcguggccg uuaguaaggu gcugcaccuu      480

gaaggugagg ucaacaaaau caaguccgcg uugcugucua caaauaaagc agugguaagc      540

cuauccaacg ggguuucagu gcucacuucu aagguccugg accuuaaaaa uuauauugau      600

aagcaacugu ugccaaucgu gaacaaacag agcuguucua uuuccaacau cgaaaccgug      660

auagaguucc agcagaagaa uaaccggcuc cuggagauua cacgcgaauu uucagucaau      720

gccggaguua ccacgccggu gagcacuuac auguuaacaa acagugagcu gcucucucuu      780

aucaaugaca ugcccauuac caacgaucaa aagaaacuga uguccaauaa cguacagauc      840

gugagacagc agagcuauuc gaucaugucu auuauaaagg aagaggucuu ggcuuacgug      900

guucaacuac cucuguacgg cgugaucgac acuccaugcu ggaaacucca uacaucccca      960

cuguguacca cgaauaccaa ggaaggcuca aacauuugcc uuacaaggac ugaucggggg     1020

ugguauugug acaaugccgg aagugucagc uucuuuccuc aggcagagac cugcaaagug     1080

caguccaacc gcguauucug ugauacaaug aauagucuga cuuugccaag cgagguuaac     1140

cucugcaaug uggacaucuu uaaccccaag uacgauugua agauaaugac cucaaaaaca     1200

gacgucaguu ccagcgugau uaccucucug ggugcuaucg ucucaugcua uggcaagacu     1260

aaaugcacgg ccaguaacaa gaaucgaggg aucauuaaaa cauucagcaa cggaugugau     1320

uacgugucca auaagggcgu ugacaccgug ucuguaggua acacuuuaua uuacgucaau     1380

aagcaagaag ggaaaucgcu guaugugaag ggagagccua ucauuaacuu uuacgacccc     1440

cuaguuuucc cgagcgauga auuugacgcg uccauaucac aggugaauga gaaaaucaac     1500

cagagucucg ccuucauuag aaagucugau gaacugcuuc acaaugucaa cgcaggcaaa     1560

agcaccacaa auaucaugau caccacuauu auaaucguga uuaucguaau uuugcugucc     1620

cucaucgcug ugggccugcu ucuguacugc aaggccaggu caacacccgu uacguugagc     1680

aaggaccagc ucucugggau aaacaauauc gcuuucucca acuga                     1725


<210>  74
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from HRSV(A2)__F0

<400>  74
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccacca acaacagagc cagaagagag cugcccagau ucaugaacua cacccugaac      360

aacgccaaga agaccaacgu gacccugagc aagaagagaa agagaagauu ccugggcuuc      420

cugcugggcg ugggcagcgc caucgccagc ggcguggccg ugagcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccagc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccaucgu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugagc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acuga                     1725


<210>  75
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from HRSV(A2)__F0

<400>  75
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacaa acaaucgggc ucgcagagag cucccucggu uuaugaacua cacccugaau      360

aacgccaaga aaacaaaugu cacccuuucu aagaaacgca agagacgguu ccugggguuu      420

cuccugggag ugggcagcgc gauugccucc gggguugcug ugagcaaggu ccuucaccug      480

gaaggagagg ugaacaaaau caagucugcc cuccugucca cgaauaaagc uguugugagc      540

cugucuaacg gcgucuccgu gcucacaagc aaggugcugg accuuaaaaa uuauauugau      600

aagcaacugc ucccgaucgu caacaaacag ucuuguucca uuagcaacau cgaaaccguu      660

auugaguucc agcagaagaa uaaccgccug cuugagauca caagagaauu uuccgugaau      720

gccggcguga ccacccccgu cucuacauac augcugacga acagcgagcu ccugucccug      780

aucaaugaca ugccuauuac caacgaucaa aagaaacuca ugagcaauaa cgugcagauc      840

guucggcagc agucuuauuc cauuaugagc aucauuaagg aagaggugcu ggcguacguc      900

gugcaacuuc cccuguacgg gguuaucgac acaccuugcu ggaaacucca uaccucuccc      960

cuguguacaa ccaauacgaa ggaaggaagc aacaucugcc uuacacgcac cgauagaggc     1020

ugguauugug acaaugccgg guccgugucu uucuuuccuc aggcugagac cugcaaaguc     1080

cagagcaacc ggguguucug ugauacaaug aacucccuga cccucccgag cgaggucaau     1140

cugugcaaug uggacauuuu uaaccccaag uacgauugua agaucaugac aucuaaaacg     1200

gacguuucca gcucugugau uaccucccug ggagccaucg ucagcugcua uggcaagaca     1260

aaaugcaccg cuuccaacaa gaaucgcggg auuaucaaaa cauucucuaa cggaugugau     1320

uacgugagca auaagggcgu ugacaccgug uccgucggca acacgcucua uuacgugaau     1380

aagcaagaag ggaaaucucu guaugugaag ggagagccua ucauuaacuu uuacgacccc     1440

cuuguuuucc cuagcgauga auuugacgcc uccaucagcc aggucaauga gaaaauuaac     1500

cagucucugg ccuucaucag aaaguccgau gaacuccugc acaaugugaa cgcuggcaaa     1560

agcaccacaa auauuaugau caccacaauu aucaucguga uuaucgucau ucugcuuucu     1620

cucaucgcgg uggggcugcu gcucuacugc aaggcccggu ccacccccgu uacgcugagc     1680

aaggaccagc uuucuggaau uaacaauauc gcuuucagca acuga                     1725


<210>  76
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from HRSV(A2)__F0

<400>  76
auggaacuuc uaauauuaaa agcuaacgca aucacuacua ucuuaaccgc aguaacauuc       60

uguuuugcau ccggccaaaa cauaacagaa gaauuuuacc aaucaacuug cucugcaguc      120

ucaaaagguu aucuaucugc auuaagaaca ggcugguaca ccucaguaau aacgaucgaa      180

cuaucaaaca ucaaagaaaa caaauguaau ggaacagacg caaaaguaaa acuaaucaaa      240

caagaacuag acaaauacaa aaacgcagua accgaacucc aacuccucau gcaaaguaca      300

ccagcaacaa auaacagagc aagacgugaa cuaccacguu uuaugaauua cacgcucaau      360

aacgcaaaaa aaacaaaugu uacccuauca aaaaaacgaa aaagaagauu ccucggauuc      420

cuacuaggcg uaggcucagc aauagcuuca ggaguagcag uaucaaaagu acuccaccuc      480

gaaggagaag uaaacaaaau caaaagcgcu cuccucucaa caaacaaagc aguuguuuca      540

cucucaaacg gaguaucagu acuaaccuca aaaguacuug accuaaaaaa uuauauagac      600

aaacaacuau uaccaauagu aaacaaacaa agcugcucca ucuccaacau cgagacaguc      660

auagaauuuc aacaaaaaaa uaaccgccua uuagaaauaa ccagagaauu uucaguaaac      720

gcaggaguaa cuaccccagu aucaacauau auguuaacaa acucagaacu ccuaagucua      780

aucaacgaca ugccaauaac caacgaccaa aaaaaacuaa ugagcaacaa uguacaaaua      840

guucgucaac aaucuuacuc cauaaugucu auaauaaaag aagaaguacu cgccuaugua      900

guccaacuac cacuauacgg agucaucgau acaccaugcu ggaaacucca cacaucccca      960

cucuguacua cuaacaccaa agaagguuca aauauaugcc uaaccagaac agauagaggu     1020

ugguacugcg auaaugcagg aucaguaucc uuuuuccccc aagccgaaac augcaaaguu     1080

caauccaaua gaguauuuug ugauacaaug aacucuuuaa cccucccauc cgaagucaau     1140

cuauguaacg ucgacauauu uaacccaaaa uacgauugca aaauaaugac aucaaaaaca     1200

gacgucucau ccucaguuau aacguccuua ggcgcuauag uaucaugcua cggcaaaaca     1260

aaauguacag caucaaacaa aaacagagga aucauaaaaa cuuucucuaa cgguugcgac     1320

uauguaucca acaaaggugu cgacacagua uccguaggca acacccuuua cuauguuaau     1380

aaacaagaag gaaaaucucu auauguaaaa ggcgaaccaa uuauaaauuu uuacgacccc     1440

cuugucuuuc ccucugacga auuugacgcu uccauaucac aagucaacga aaaaaucaac     1500

caaucccucg cauucauacg caaaucagac gaacuacuac auaacgucaa cgcaggcaaa     1560

uccacaacaa acauaaugau aaccacaauc auaauuguaa uaauaguaau acuacuuucu     1620

cuaauagcag ucggauuacu cuuauacugu aaagcucgau caacaccagu cacccucucu     1680

aaagaucaac uauccggaau caacaacaua gcuuucucaa acuaa                     1725


<210>  77
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from HRSV(A2)__F0

<400>  77
auggaacucc ucauacucaa agccaacgca aucacaacca uacucaccgc cgucaccuuc       60

ugcuuugcau cuggccagaa caucacugaa gaguucuacc aauccacaug cuccgccgua      120

agcaaaggcu accuauccgc ccuacgcacc ggcugguaca ccagcguaau caccauagaa      180

cucuccaaua uaaaagaaaa caaaugcaac ggcaccgacg caaaagucaa gcuaauaaaa      240

caagaacucg acaaauacaa aaacgccguu accgaacucc agcuacucau gcaaucgacc      300

ccagcaacca acaaccgugc gagacgcgaa cucccccgcu ucaugaacua cacccuaaac      360

aacgccaaaa agaccaacgu aacucuaucc aagaaacgca aacgccgcuu ccucggauuc      420

cuccucggcg ucggcuccgc aaucgccagc ggcgucgccg uuagcaaagu ccuucaccuc      480

gaaggagaag uaaacaaaau uaaaagcgcc cucuuaucca caaacaaggc cguaguaucc      540

cugucaaacg gcgucuccgu ccuuacaucc aaaguccucg accucaagaa cuacauagac      600

aaacagcuac uacccauugu aaauaaacaa agcugcucaa uuagcaacau cgaaaccgua      660

aucgaguucc agcagaaaaa caacagacuu cucgaaauca cccgcgaguu cagcgucaac      720

gccggcguaa ccaccccugu cucaacauac augcuaacca acagcgaacu gcucucccuc      780

aucaacgaca ugcccaucac caacgaccaa aagaaacuca ugagcaacaa cguacaaauc      840

gugcgccaac aguccuacuc aauaauguca aucaucaaag aagaagugcu agcauacguc      900

guacaacuac cacucuacgg cguaauagau acccccugcu ggaagcucca uaccucccca      960

cucuguacca ccaacaccaa agaaggcuca aacaucugcc uaacgcgcac agaccgugga     1020

ugguacugug acaacgccgg cuccgucucc uucuucccuc aagccgaaac augcaaaguc     1080

caauccaaca gagucuucug cgauaccaug aacucccuga cacucccaag cgaagucaac     1140

cuuugcaacg ucgauaucuu uaaccccaaa uacgacugca agaucaugac aucaaaaacc     1200

gacguauccu ccucuguaau aaccucccua ggcgcaaucg uaucaugcua cggcaaaacc     1260

aaauguaccg ccuccaacaa aaaucgcggc aucaucaaaa ccuucucgaa cggcugcgac     1320

uacgucucca acaaaggcgu agacacaguu uccguaggca acacccucua cuacgucaau     1380

aaacaggaag gcaagucccu cuacgucaaa ggcgaaccca ucaucaauuu cuacgacccc     1440

cucguuuucc ccuccgauga guucgacgca agcaucagcc aggucaacga aaagauaaac     1500

cagucccucg ccuucauccg caaaucagau gaacuccuuc acaacguuaa cgcaggcaag     1560

agcaccacca acaucaugau cacaacuaua aucaucguca uaaucgucau ccuacucuca     1620

cuaaucgccg ucggucuccu acuauauugu aaagcccgau caacaccggu cacacucucc     1680

aaagaccaac ucuccggaau caacaauauc gcuuucucga acuaa                     1725


<210>  78
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  78
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagaagca     1740

caccagucac acuaagcaaa gaucaacuga gugguauaaa uaauauugca uuuaguaacu     1800

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  79
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  79
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  80
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  80
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca     1740

cgcccgugac ccuguccaag gaccagcuga gcggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  81
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  81
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  82
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  82
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggucaa     1740

cacccguuac guugagcaag gaccagcucu cugggauaaa caauaucgcu uucuccaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  83
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  83
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  84
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  84
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggucca     1740

cccccguuac gcugagcaag gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  85
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  85
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu      120

uaaccgcagu aacauucugu uuugcauccg gccaaaacau aacagaagaa uuuuaccaau      180

caacuugcuc ugcagucuca aaagguuauc uaucugcauu aagaacaggc ugguacaccu      240

caguaauaac gaucgaacua ucaaacauca aagaaaacaa auguaaugga acagacgcaa      300

aaguaaaacu aaucaaacaa gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac      360

uccucaugca aaguacacca gcaacaaaua acagagcaag acgugaacua ccacguuuua      420

ugaauuacac gcucaauaac gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa      480

gaagauuccu cggauuccua cuaggcguag gcucagcaau agcuucagga guagcaguau      540

caaaaguacu ccaccucgaa ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa      600

acaaagcagu uguuucacuc ucaaacggag uaucaguacu aaccucaaaa guacuugacc      660

uaaaaaauua uauagacaaa caacuauuac caauaguaaa caaacaaagc ugcuccaucu      720

ccaacaucga gacagucaua gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca      780

gagaauuuuc aguaaacgca ggaguaacua ccccaguauc aacauauaug uuaacaaacu      840

cagaacuccu aagucuaauc aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga      900

gcaacaaugu acaaauaguu cgucaacaau cuuacuccau aaugucuaua auaaaagaag      960

aaguacucgc cuauguaguc caacuaccac uauacggagu caucgauaca ccaugcugga     1020

aacuccacac auccccacuc uguacuacua acaccaaaga agguucaaau auaugccuaa     1080

ccagaacaga uagagguugg uacugcgaua augcaggauc aguauccuuu uucccccaag     1140

ccgaaacaug caaaguucaa uccaauagag uauuuuguga uacaaugaac ucuuuaaccc     1200

ucccauccga agucaaucua uguaacgucg acauauuuaa cccaaaauac gauugcaaaa     1260

uaaugacauc aaaaacagac gucucauccu caguuauaac guccuuaggc gcuauaguau     1320

caugcuacgg caaaacaaaa uguacagcau caaacaaaaa cagaggaauc auaaaaacuu     1380

ucucuaacgg uugcgacuau guauccaaca aaggugucga cacaguaucc guaggcaaca     1440

cccuuuacua uguuaauaaa caagaaggaa aaucucuaua uguaaaaggc gaaccaauua     1500

uaaauuuuua cgacccccuu gucuuucccu cugacgaauu ugacgcuucc auaucacaag     1560

ucaacgaaaa aaucaaccaa ucccucgcau ucauacgcaa aucagacgaa cuacuacaua     1620

acgucaacgc aggcaaaucc acaacaaaca uaaugauaac cacaaucaua auuguaauaa     1680

uaguaauacu acuuucucua auagcagucg gauuacucuu auacuguaaa gcucgaucaa     1740

caccagucac ccucucuaaa gaucaacuau ccggaaucaa caacauagcu uucucaaacu     1800

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  86
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  86
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uacucaaagc caacgcaauc acaaccauac      120

ucaccgccgu caccuucugc uuugcaucug gccagaacau cacugaagag uucuaccaau      180

ccacaugcuc cgccguaagc aaaggcuacc uauccgcccu acgcaccggc ugguacacca      240

gcguaaucac cauagaacuc uccaauauaa aagaaaacaa augcaacggc accgacgcaa      300

aagucaagcu aauaaaacaa gaacucgaca aauacaaaaa cgccguuacc gaacuccagc      360

uacucaugca aucgacccca gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca      420

ugaacuacac ccuaaacaac gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac      480

gccgcuuccu cggauuccuc cucggcgucg gcuccgcaau cgccagcggc gucgccguua      540

gcaaaguccu ucaccucgaa ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa      600

acaaggccgu aguaucccug ucaaacggcg ucuccguccu uacauccaaa guccucgacc      660

ucaagaacua cauagacaaa cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua      720

gcaacaucga aaccguaauc gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc      780

gcgaguucag cgucaacgcc ggcguaacca ccccugucuc aacauacaug cuaaccaaca      840

gcgaacugcu cucccucauc aacgacaugc ccaucaccaa cgaccaaaag aaacucauga      900

gcaacaacgu acaaaucgug cgccaacagu ccuacucaau aaugucaauc aucaaagaag      960

aagugcuagc auacgucgua caacuaccac ucuacggcgu aauagauacc cccugcugga     1020

agcuccauac cuccccacuc uguaccacca acaccaaaga aggcucaaac aucugccuaa     1080

cgcgcacaga ccguggaugg uacugugaca acgccggcuc cgucuccuuc uucccucaag     1140

ccgaaacaug caaaguccaa uccaacagag ucuucugcga uaccaugaac ucccugacac     1200

ucccaagcga agucaaccuu ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga     1260

ucaugacauc aaaaaccgac guauccuccu cuguaauaac cucccuaggc gcaaucguau     1320

caugcuacgg caaaaccaaa uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu     1380

ucucgaacgg cugcgacuac gucuccaaca aaggcguaga cacaguuucc guaggcaaca     1440

cccucuacua cgucaauaaa caggaaggca agucccucua cgucaaaggc gaacccauca     1500

ucaauuucua cgacccccuc guuuuccccu ccgaugaguu cgacgcaagc aucagccagg     1560

ucaacgaaaa gauaaaccag ucccucgccu ucauccgcaa aucagaugaa cuccuucaca     1620

acguuaacgc aggcaagagc accaccaaca ucaugaucac aacuauaauc aucgucauaa     1680

ucgucauccu acucucacua aucgccgucg gucuccuacu auauuguaaa gcccgaucaa     1740

caccggucac acucuccaaa gaccaacucu ccggaaucaa caauaucgcu uucucgaacu     1800

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  87
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  87
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagaagcac accagucaca cuaagcaaag aucaacugag ugguauaaau     1800

aauauugcau uuaguaacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  88
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  88
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  89
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  89
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcagcac gcccgugacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgccu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  90
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  90
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  91
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  91
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggucaac acccguuacg uugagcaagg accagcucuc ugggauaaac     1800

aauaucgcuu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  92
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  92
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  93
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  93
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccgguccac ccccguuacg cugagcaagg accagcuuuc uggaauuaac     1800

aauaucgcuu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  94
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  94
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau auuaaaagcu      120

aacgcaauca cuacuaucuu aaccgcagua acauucuguu uugcauccgg ccaaaacaua      180

acagaagaau uuuaccaauc aacuugcucu gcagucucaa aagguuaucu aucugcauua      240

agaacaggcu gguacaccuc aguaauaacg aucgaacuau caaacaucaa agaaaacaaa      300

uguaauggaa cagacgcaaa aguaaaacua aucaaacaag aacuagacaa auacaaaaac      360

gcaguaaccg aacuccaacu ccucaugcaa aguacaccag caacaaauaa cagagcaaga      420

cgugaacuac cacguuuuau gaauuacacg cucaauaacg caaaaaaaac aaauguuacc      480

cuaucaaaaa aacgaaaaag aagauuccuc ggauuccuac uaggcguagg cucagcaaua      540

gcuucaggag uagcaguauc aaaaguacuc caccucgaag gagaaguaaa caaaaucaaa      600

agcgcucucc ucucaacaaa caaagcaguu guuucacucu caaacggagu aucaguacua      660

accucaaaag uacuugaccu aaaaaauuau auagacaaac aacuauuacc aauaguaaac      720

aaacaaagcu gcuccaucuc caacaucgag acagucauag aauuucaaca aaaaaauaac      780

cgccuauuag aaauaaccag agaauuuuca guaaacgcag gaguaacuac cccaguauca      840

acauauaugu uaacaaacuc agaacuccua agucuaauca acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaaugag caacaaugua caaauaguuc gucaacaauc uuacuccaua      960

augucuauaa uaaaagaaga aguacucgcc uauguagucc aacuaccacu auacggaguc     1020

aucgauacac caugcuggaa acuccacaca uccccacucu guacuacuaa caccaaagaa     1080

gguucaaaua uaugccuaac cagaacagau agagguuggu acugcgauaa ugcaggauca     1140

guauccuuuu ucccccaagc cgaaacaugc aaaguucaau ccaauagagu auuuugugau     1200

acaaugaacu cuuuaacccu cccauccgaa gucaaucuau guaacgucga cauauuuaac     1260

ccaaaauacg auugcaaaau aaugacauca aaaacagacg ucucauccuc aguuauaacg     1320

uccuuaggcg cuauaguauc augcuacggc aaaacaaaau guacagcauc aaacaaaaac     1380

agaggaauca uaaaaacuuu cucuaacggu ugcgacuaug uauccaacaa aggugucgac     1440

acaguauccg uaggcaacac ccuuuacuau guuaauaaac aagaaggaaa aucucuauau     1500

guaaaaggcg aaccaauuau aaauuuuuac gacccccuug ucuuucccuc ugacgaauuu     1560

gacgcuucca uaucacaagu caacgaaaaa aucaaccaau cccucgcauu cauacgcaaa     1620

ucagacgaac uacuacauaa cgucaacgca ggcaaaucca caacaaacau aaugauaacc     1680

acaaucauaa uuguaauaau aguaauacua cuuucucuaa uagcagucgg auuacucuua     1740

uacuguaaag cucgaucaac accagucacc cucucuaaag aucaacuauc cggaaucaac     1800

aacauagcuu ucucaaacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  95
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  95
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau acucaaagcc      120

aacgcaauca caaccauacu caccgccguc accuucugcu uugcaucugg ccagaacauc      180

acugaagagu ucuaccaauc cacaugcucc gccguaagca aaggcuaccu auccgcccua      240

cgcaccggcu gguacaccag cguaaucacc auagaacucu ccaauauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa agucaagcua auaaaacaag aacucgacaa auacaaaaac      360

gccguuaccg aacuccagcu acucaugcaa ucgaccccag caaccaacaa ccgugcgaga      420

cgcgaacucc cccgcuucau gaacuacacc cuaaacaacg ccaaaaagac caacguaacu      480

cuauccaaga aacgcaaacg ccgcuuccuc ggauuccucc ucggcgucgg cuccgcaauc      540

gccagcggcg ucgccguuag caaaguccuu caccucgaag gagaaguaaa caaaauuaaa      600

agcgcccucu uauccacaaa caaggccgua guaucccugu caaacggcgu cuccguccuu      660

acauccaaag uccucgaccu caagaacuac auagacaaac agcuacuacc cauuguaaau      720

aaacaaagcu gcucaauuag caacaucgaa accguaaucg aguuccagca gaaaaacaac      780

agacuucucg aaaucacccg cgaguucagc gucaacgccg gcguaaccac cccugucuca      840

acauacaugc uaaccaacag cgaacugcuc ucccucauca acgacaugcc caucaccaac      900

gaccaaaaga aacucaugag caacaacgua caaaucgugc gccaacaguc cuacucaaua      960

augucaauca ucaaagaaga agugcuagca uacgucguac aacuaccacu cuacggcgua     1020

auagauaccc ccugcuggaa gcuccauacc uccccacucu guaccaccaa caccaaagaa     1080

ggcucaaaca ucugccuaac gcgcacagac cguggauggu acugugacaa cgccggcucc     1140

gucuccuucu ucccucaagc cgaaacaugc aaaguccaau ccaacagagu cuucugcgau     1200

accaugaacu cccugacacu cccaagcgaa gucaaccuuu gcaacgucga uaucuuuaac     1260

cccaaauacg acugcaagau caugacauca aaaaccgacg uauccuccuc uguaauaacc     1320

ucccuaggcg caaucguauc augcuacggc aaaaccaaau guaccgccuc caacaaaaau     1380

cgcggcauca ucaaaaccuu cucgaacggc ugcgacuacg ucuccaacaa aggcguagac     1440

acaguuuccg uaggcaacac ccucuacuac gucaauaaac aggaaggcaa gucccucuac     1500

gucaaaggcg aacccaucau caauuucuac gacccccucg uuuuccccuc cgaugaguuc     1560

gacgcaagca ucagccaggu caacgaaaag auaaaccagu cccucgccuu cauccgcaaa     1620

ucagaugaac uccuucacaa cguuaacgca ggcaagagca ccaccaacau caugaucaca     1680

acuauaauca ucgucauaau cgucauccua cucucacuaa ucgccgucgg ucuccuacua     1740

uauuguaaag cccgaucaac accggucaca cucuccaaag accaacucuc cggaaucaac     1800

aauaucgcuu ucucgaacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  96
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  96
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agaagcacac cagucacacu aagcaaagau     1860

caacugagug guauaaauaa uauugcauuu aguaacuaag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  97
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  97
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  98
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  98
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcagcacgc ccgugacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc uccaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  99
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  99
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  100
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  100
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggucaacac ccguuacguu gagcaaggac     1860

cagcucucug ggauaaacaa uaucgcuuuc uccaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  101
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  101
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  102
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  102
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cgguccaccc ccguuacgcu gagcaaggac     1860

cagcuuucug gaauuaacaa uaucgcuuuc agcaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  103
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  103
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauau uaaaagcuaa cgcaaucacu acuaucuuaa ccgcaguaac auucuguuuu      240

gcauccggcc aaaacauaac agaagaauuu uaccaaucaa cuugcucugc agucucaaaa      300

gguuaucuau cugcauuaag aacaggcugg uacaccucag uaauaacgau cgaacuauca      360

aacaucaaag aaaacaaaug uaauggaaca gacgcaaaag uaaaacuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguaaccgaa cuccaacucc ucaugcaaag uacaccagca      480

acaaauaaca gagcaagacg ugaacuacca cguuuuauga auuacacgcu caauaacgca      540

aaaaaaacaa auguuacccu aucaaaaaaa cgaaaaagaa gauuccucgg auuccuacua      600

ggcguaggcu cagcaauagc uucaggagua gcaguaucaa aaguacucca ccucgaagga      660

gaaguaaaca aaaucaaaag cgcucuccuc ucaacaaaca aagcaguugu uucacucuca      720

aacggaguau caguacuaac cucaaaagua cuugaccuaa aaaauuauau agacaaacaa      780

cuauuaccaa uaguaaacaa acaaagcugc uccaucucca acaucgagac agucauagaa      840

uuucaacaaa aaaauaaccg ccuauuagaa auaaccagag aauuuucagu aaacgcagga      900

guaacuaccc caguaucaac auauauguua acaaacucag aacuccuaag ucuaaucaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugagca acaauguaca aauaguucgu     1020

caacaaucuu acuccauaau gucuauaaua aaagaagaag uacucgccua uguaguccaa     1080

cuaccacuau acggagucau cgauacacca ugcuggaaac uccacacauc cccacucugu     1140

acuacuaaca ccaaagaagg uucaaauaua ugccuaacca gaacagauag agguugguac     1200

ugcgauaaug caggaucagu auccuuuuuc ccccaagccg aaacaugcaa aguucaaucc     1260

aauagaguau uuugugauac aaugaacucu uuaacccucc cauccgaagu caaucuaugu     1320

aacgucgaca uauuuaaccc aaaauacgau ugcaaaauaa ugacaucaaa aacagacguc     1380

ucauccucag uuauaacguc cuuaggcgcu auaguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa acaaaaacag aggaaucaua aaaacuuucu cuaacgguug cgacuaugua     1500

uccaacaaag gugucgacac aguauccgua ggcaacaccc uuuacuaugu uaauaaacaa     1560

gaaggaaaau cucuauaugu aaaaggcgaa ccaauuauaa auuuuuacga cccccuuguc     1620

uuucccucug acgaauuuga cgcuuccaua ucacaaguca acgaaaaaau caaccaaucc     1680

cucgcauuca uacgcaaauc agacgaacua cuacauaacg ucaacgcagg caaauccaca     1740

acaaacauaa ugauaaccac aaucauaauu guaauaauag uaauacuacu uucucuaaua     1800

gcagucggau uacucuuaua cuguaaagcu cgaucaacac cagucacccu cucuaaagau     1860

caacuauccg gaaucaacaa cauagcuuuc ucaaacuaag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  104
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  104
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucauac ucaaagccaa cgcaaucaca accauacuca ccgccgucac cuucugcuuu      240

gcaucuggcc agaacaucac ugaagaguuc uaccaaucca caugcuccgc cguaagcaaa      300

ggcuaccuau ccgcccuacg caccggcugg uacaccagcg uaaucaccau agaacucucc      360

aauauaaaag aaaacaaaug caacggcacc gacgcaaaag ucaagcuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cguuaccgaa cuccagcuac ucaugcaauc gaccccagca      480

accaacaacc gugcgagacg cgaacucccc cgcuucauga acuacacccu aaacaacgcc      540

aaaaagacca acguaacucu auccaagaaa cgcaaacgcc gcuuccucgg auuccuccuc      600

ggcgucggcu ccgcaaucgc cagcggcguc gccguuagca aaguccuuca ccucgaagga      660

gaaguaaaca aaauuaaaag cgcccucuua uccacaaaca aggccguagu aucccuguca      720

aacggcgucu ccguccuuac auccaaaguc cucgaccuca agaacuacau agacaaacag      780

cuacuaccca uuguaaauaa acaaagcugc ucaauuagca acaucgaaac cguaaucgag      840

uuccagcaga aaaacaacag acuucucgaa aucacccgcg aguucagcgu caacgccggc      900

guaaccaccc cugucucaac auacaugcua accaacagcg aacugcucuc ccucaucaac      960

gacaugccca ucaccaacga ccaaaagaaa cucaugagca acaacguaca aaucgugcgc     1020

caacaguccu acucaauaau gucaaucauc aaagaagaag ugcuagcaua cgucguacaa     1080

cuaccacucu acggcguaau agauaccccc ugcuggaagc uccauaccuc cccacucugu     1140

accaccaaca ccaaagaagg cucaaacauc ugccuaacgc gcacagaccg uggaugguac     1200

ugugacaacg ccggcuccgu cuccuucuuc ccucaagccg aaacaugcaa aguccaaucc     1260

aacagagucu ucugcgauac caugaacucc cugacacucc caagcgaagu caaccuuugc     1320

aacgucgaua ucuuuaaccc caaauacgac ugcaagauca ugacaucaaa aaccgacgua     1380

uccuccucug uaauaaccuc ccuaggcgca aucguaucau gcuacggcaa aaccaaaugu     1440

accgccucca acaaaaaucg cggcaucauc aaaaccuucu cgaacggcug cgacuacguc     1500

uccaacaaag gcguagacac aguuuccgua ggcaacaccc ucuacuacgu caauaaacag     1560

gaaggcaagu cccucuacgu caaaggcgaa cccaucauca auuucuacga cccccucguu     1620

uuccccuccg augaguucga cgcaagcauc agccagguca acgaaaagau aaaccagucc     1680

cucgccuuca uccgcaaauc agaugaacuc cuucacaacg uuaacgcagg caagagcacc     1740

accaacauca ugaucacaac uauaaucauc gucauaaucg ucauccuacu cucacuaauc     1800

gccgucgguc uccuacuaua uuguaaagcc cgaucaacac cggucacacu cuccaaagac     1860

caacucuccg gaaucaacaa uaucgcuuuc ucgaacuaag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  105
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  105
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gaagcacacc agucacacua     1800

agcaaagauc aacugagugg uauaaauaau auugcauuua guaacuaagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  106
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  106
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  107
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  107
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcagcacgcc cgugacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgccuucu ccaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  108
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  108
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  109
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  109
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggucaacacc cguuacguug     1800

agcaaggacc agcucucugg gauaaacaau aucgcuuucu ccaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  110
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  110
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  111
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  111
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc gguccacccc cguuacgcug     1800

agcaaggacc agcuuucugg aauuaacaau aucgcuuuca gcaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  112
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  112
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauauu aaaagcuaac gcaaucacua cuaucuuaac cgcaguaaca      180

uucuguuuug cauccggcca aaacauaaca gaagaauuuu accaaucaac uugcucugca      240

gucucaaaag guuaucuauc ugcauuaaga acaggcuggu acaccucagu aauaacgauc      300

gaacuaucaa acaucaaaga aaacaaaugu aauggaacag acgcaaaagu aaaacuaauc      360

aaacaagaac uagacaaaua caaaaacgca guaaccgaac uccaacuccu caugcaaagu      420

acaccagcaa caaauaacag agcaagacgu gaacuaccac guuuuaugaa uuacacgcuc      480

aauaacgcaa aaaaaacaaa uguuacccua ucaaaaaaac gaaaaagaag auuccucgga      540

uuccuacuag gcguaggcuc agcaauagcu ucaggaguag caguaucaaa aguacuccac      600

cucgaaggag aaguaaacaa aaucaaaagc gcucuccucu caacaaacaa agcaguuguu      660

ucacucucaa acggaguauc aguacuaacc ucaaaaguac uugaccuaaa aaauuauaua      720

gacaaacaac uauuaccaau aguaaacaaa caaagcugcu ccaucuccaa caucgagaca      780

gucauagaau uucaacaaaa aaauaaccgc cuauuagaaa uaaccagaga auuuucagua      840

aacgcaggag uaacuacccc aguaucaaca uauauguuaa caaacucaga acuccuaagu      900

cuaaucaacg acaugccaau aaccaacgac caaaaaaaac uaaugagcaa caauguacaa      960

auaguucguc aacaaucuua cuccauaaug ucuauaauaa aagaagaagu acucgccuau     1020

guaguccaac uaccacuaua cggagucauc gauacaccau gcuggaaacu ccacacaucc     1080

ccacucugua cuacuaacac caaagaaggu ucaaauauau gccuaaccag aacagauaga     1140

gguugguacu gcgauaaugc aggaucagua uccuuuuucc cccaagccga aacaugcaaa     1200

guucaaucca auagaguauu uugugauaca augaacucuu uaacccuccc auccgaaguc     1260

aaucuaugua acgucgacau auuuaaccca aaauacgauu gcaaaauaau gacaucaaaa     1320

acagacgucu cauccucagu uauaacgucc uuaggcgcua uaguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa caaaaacaga ggaaucauaa aaacuuucuc uaacgguugc     1440

gacuauguau ccaacaaagg ugucgacaca guauccguag gcaacacccu uuacuauguu     1500

aauaaacaag aaggaaaauc ucuauaugua aaaggcgaac caauuauaaa uuuuuacgac     1560

ccccuugucu uucccucuga cgaauuugac gcuuccauau cacaagucaa cgaaaaaauc     1620

aaccaauccc ucgcauucau acgcaaauca gacgaacuac uacauaacgu caacgcaggc     1680

aaauccacaa caaacauaau gauaaccaca aucauaauug uaauaauagu aauacuacuu     1740

ucucuaauag cagucggauu acucuuauac uguaaagcuc gaucaacacc agucacccuc     1800

ucuaaagauc aacuauccgg aaucaacaac auagcuuucu caaacuaagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  113
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  113
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauacu caaagccaac gcaaucacaa ccauacucac cgccgucacc      180

uucugcuuug caucuggcca gaacaucacu gaagaguucu accaauccac augcuccgcc      240

guaagcaaag gcuaccuauc cgcccuacgc accggcuggu acaccagcgu aaucaccaua      300

gaacucucca auauaaaaga aaacaaaugc aacggcaccg acgcaaaagu caagcuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc guuaccgaac uccagcuacu caugcaaucg      420

accccagcaa ccaacaaccg ugcgagacgc gaacuccccc gcuucaugaa cuacacccua      480

aacaacgcca aaaagaccaa cguaacucua uccaagaaac gcaaacgccg cuuccucgga      540

uuccuccucg gcgucggcuc cgcaaucgcc agcggcgucg ccguuagcaa aguccuucac      600

cucgaaggag aaguaaacaa aauuaaaagc gcccucuuau ccacaaacaa ggccguagua      660

ucccugucaa acggcgucuc cguccuuaca uccaaagucc ucgaccucaa gaacuacaua      720

gacaaacagc uacuacccau uguaaauaaa caaagcugcu caauuagcaa caucgaaacc      780

guaaucgagu uccagcagaa aaacaacaga cuucucgaaa ucacccgcga guucagcguc      840

aacgccggcg uaaccacccc ugucucaaca uacaugcuaa ccaacagcga acugcucucc      900

cucaucaacg acaugcccau caccaacgac caaaagaaac ucaugagcaa caacguacaa      960

aucgugcgcc aacaguccua cucaauaaug ucaaucauca aagaagaagu gcuagcauac     1020

gucguacaac uaccacucua cggcguaaua gauacccccu gcuggaagcu ccauaccucc     1080

ccacucugua ccaccaacac caaagaaggc ucaaacaucu gccuaacgcg cacagaccgu     1140

ggaugguacu gugacaacgc cggcuccguc uccuucuucc cucaagccga aacaugcaaa     1200

guccaaucca acagagucuu cugcgauacc augaacuccc ugacacuccc aagcgaaguc     1260

aaccuuugca acgucgauau cuuuaacccc aaauacgacu gcaagaucau gacaucaaaa     1320

accgacguau ccuccucugu aauaaccucc cuaggcgcaa ucguaucaug cuacggcaaa     1380

accaaaugua ccgccuccaa caaaaaucgc ggcaucauca aaaccuucuc gaacggcugc     1440

gacuacgucu ccaacaaagg cguagacaca guuuccguag gcaacacccu cuacuacguc     1500

aauaaacagg aaggcaaguc ccucuacguc aaaggcgaac ccaucaucaa uuucuacgac     1560

ccccucguuu uccccuccga ugaguucgac gcaagcauca gccaggucaa cgaaaagaua     1620

aaccaguccc ucgccuucau ccgcaaauca gaugaacucc uucacaacgu uaacgcaggc     1680

aagagcacca ccaacaucau gaucacaacu auaaucaucg ucauaaucgu cauccuacuc     1740

ucacuaaucg ccgucggucu ccuacuauau uguaaagccc gaucaacacc ggucacacuc     1800

uccaaagacc aacucuccgg aaucaacaau aucgcuuucu cgaacuaagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  114
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  114
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaag cacaccaguc     1740

acacuaagca aagaucaacu gagugguaua aauaauauug cauuuaguaa cuaaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  115
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  115
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  116
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  116
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcag cacgcccgug     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg ccuucuccaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  117
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  117
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  118
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  118
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccagguc aacacccguu     1740

acguugagca aggaccagcu cucugggaua aacaauaucg cuuucuccaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  119
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  119
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  120
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  120
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccgguc cacccccguu     1740

acgcugagca aggaccagcu uucuggaauu aacaauaucg cuuucagcaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  121
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  121
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauauuaaaa gcuaacgcaa ucacuacuau cuuaaccgca      120

guaacauucu guuuugcauc cggccaaaac auaacagaag aauuuuacca aucaacuugc      180

ucugcagucu caaaagguua ucuaucugca uuaagaacag gcugguacac cucaguaaua      240

acgaucgaac uaucaaacau caaagaaaac aaauguaaug gaacagacgc aaaaguaaaa      300

cuaaucaaac aagaacuaga caaauacaaa aacgcaguaa ccgaacucca acuccucaug      360

caaaguacac cagcaacaaa uaacagagca agacgugaac uaccacguuu uaugaauuac      420

acgcucaaua acgcaaaaaa aacaaauguu acccuaucaa aaaaacgaaa aagaagauuc      480

cucggauucc uacuaggcgu aggcucagca auagcuucag gaguagcagu aucaaaagua      540

cuccaccucg aaggagaagu aaacaaaauc aaaagcgcuc uccucucaac aaacaaagca      600

guuguuucac ucucaaacgg aguaucagua cuaaccucaa aaguacuuga ccuaaaaaau      660

uauauagaca aacaacuauu accaauagua aacaaacaaa gcugcuccau cuccaacauc      720

gagacaguca uagaauuuca acaaaaaaau aaccgccuau uagaaauaac cagagaauuu      780

ucaguaaacg caggaguaac uaccccagua ucaacauaua uguuaacaaa cucagaacuc      840

cuaagucuaa ucaacgacau gccaauaacc aacgaccaaa aaaaacuaau gagcaacaau      900

guacaaauag uucgucaaca aucuuacucc auaaugucua uaauaaaaga agaaguacuc      960

gccuauguag uccaacuacc acuauacgga gucaucgaua caccaugcug gaaacuccac     1020

acauccccac ucuguacuac uaacaccaaa gaagguucaa auauaugccu aaccagaaca     1080

gauagagguu gguacugcga uaaugcagga ucaguauccu uuuuccccca agccgaaaca     1140

ugcaaaguuc aauccaauag aguauuuugu gauacaauga acucuuuaac ccucccaucc     1200

gaagucaauc uauguaacgu cgacauauuu aacccaaaau acgauugcaa aauaaugaca     1260

ucaaaaacag acgucucauc cucaguuaua acguccuuag gcgcuauagu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaacaaa aacagaggaa ucauaaaaac uuucucuaac     1380

gguugcgacu auguauccaa caaagguguc gacacaguau ccguaggcaa cacccuuuac     1440

uauguuaaua aacaagaagg aaaaucucua uauguaaaag gcgaaccaau uauaaauuuu     1500

uacgaccccc uugucuuucc cucugacgaa uuugacgcuu ccauaucaca agucaacgaa     1560

aaaaucaacc aaucccucgc auucauacgc aaaucagacg aacuacuaca uaacgucaac     1620

gcaggcaaau ccacaacaaa cauaaugaua accacaauca uaauuguaau aauaguaaua     1680

cuacuuucuc uaauagcagu cggauuacuc uuauacugua aagcucgauc aacaccaguc     1740

acccucucua aagaucaacu auccggaauc aacaacauag cuuucucaaa cuaaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  122
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  122
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauacucaaa gccaacgcaa ucacaaccau acucaccgcc      120

gucaccuucu gcuuugcauc uggccagaac aucacugaag aguucuacca auccacaugc      180

uccgccguaa gcaaaggcua ccuauccgcc cuacgcaccg gcugguacac cagcguaauc      240

accauagaac ucuccaauau aaaagaaaac aaaugcaacg gcaccgacgc aaaagucaag      300

cuaauaaaac aagaacucga caaauacaaa aacgccguua ccgaacucca gcuacucaug      360

caaucgaccc cagcaaccaa caaccgugcg agacgcgaac ucccccgcuu caugaacuac      420

acccuaaaca acgccaaaaa gaccaacgua acucuaucca agaaacgcaa acgccgcuuc      480

cucggauucc uccucggcgu cggcuccgca aucgccagcg gcgucgccgu uagcaaaguc      540

cuucaccucg aaggagaagu aaacaaaauu aaaagcgccc ucuuauccac aaacaaggcc      600

guaguauccc ugucaaacgg cgucuccguc cuuacaucca aaguccucga ccucaagaac      660

uacauagaca aacagcuacu acccauugua aauaaacaaa gcugcucaau uagcaacauc      720

gaaaccguaa ucgaguucca gcagaaaaac aacagacuuc ucgaaaucac ccgcgaguuc      780

agcgucaacg ccggcguaac caccccuguc ucaacauaca ugcuaaccaa cagcgaacug      840

cucucccuca ucaacgacau gcccaucacc aacgaccaaa agaaacucau gagcaacaac      900

guacaaaucg ugcgccaaca guccuacuca auaaugucaa ucaucaaaga agaagugcua      960

gcauacgucg uacaacuacc acucuacggc guaauagaua cccccugcug gaagcuccau     1020

accuccccac ucuguaccac caacaccaaa gaaggcucaa acaucugccu aacgcgcaca     1080

gaccguggau gguacuguga caacgccggc uccgucuccu ucuucccuca agccgaaaca     1140

ugcaaagucc aauccaacag agucuucugc gauaccauga acucccugac acucccaagc     1200

gaagucaacc uuugcaacgu cgauaucuuu aaccccaaau acgacugcaa gaucaugaca     1260

ucaaaaaccg acguauccuc cucuguaaua accucccuag gcgcaaucgu aucaugcuac     1320

ggcaaaacca aauguaccgc cuccaacaaa aaucgcggca ucaucaaaac cuucucgaac     1380

ggcugcgacu acgucuccaa caaaggcgua gacacaguuu ccguaggcaa cacccucuac     1440

uacgucaaua aacaggaagg caagucccuc uacgucaaag gcgaacccau caucaauuuc     1500

uacgaccccc ucguuuuccc cuccgaugag uucgacgcaa gcaucagcca ggucaacgaa     1560

aagauaaacc agucccucgc cuucauccgc aaaucagaug aacuccuuca caacguuaac     1620

gcaggcaaga gcaccaccaa caucaugauc acaacuauaa ucaucgucau aaucgucauc     1680

cuacucucac uaaucgccgu cggucuccua cuauauugua aagcccgauc aacaccgguc     1740

acacucucca aagaccaacu cuccggaauc aacaauaucg cuuucucgaa cuaaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  123
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  123
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      300

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      360

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      420

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      480

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      540

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      600

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      660

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      720

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      780

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      840

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      900

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      960

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc     1020

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu     1080

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua     1140

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1200

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1260

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1320

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1380

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1440

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1500

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1560

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1620

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1680

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1740

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1800

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1860

auugcuguug gacugcucuu auacuguaag gccagaagca caccagucac acuaagcaaa     1920

gaucaacuga gugguauaaa uaauauugca uuuaguaacu aaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  124
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  124
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      660

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      720

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      780

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      900

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      960

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc     1020

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc     1080

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc     1140

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1200

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1260

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1320

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1500

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1620

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1680

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1800

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1860

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1920

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  125
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  125
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      660

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      720

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      780

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      900

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      960

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc     1080

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc     1140

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1200

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1260

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1320

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1380

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1500

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1620

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1680

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1740

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1800

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1860

aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca cgcccgugac ccuguccaag     1920

gaccagcuga gcggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  126
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  126
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      600

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      660

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      720

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      780

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      840

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      900

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      960

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc     1080

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc     1140

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1200

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1260

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1320

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1500

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1560

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1620

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1680

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1740

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1800

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1860

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1920

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  127
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  127
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      600

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      660

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      720

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      780

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      840

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      900

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      960

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc     1020

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug     1080

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu     1140

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1200

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1260

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1320

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1380

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1440

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1500

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1560

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1620

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1680

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1740

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1800

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1860

aucgcugugg gccugcuucu guacugcaag gccaggucaa cacccguuac guugagcaag     1920

gaccagcucu cugggauaaa caauaucgcu uucuccaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  128
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  128
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      600

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      660

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      720

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      780

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      840

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      900

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      960

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug     1080

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug     1140

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1200

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1260

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1320

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1380

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1440

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1500

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1620

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1680

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1800

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1860

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1920

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  129
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  129
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      600

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      660

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      720

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      780

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      840

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      900

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      960

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc     1020

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu     1080

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug     1140

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1200

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1260

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1320

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1380

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1440

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1500

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1560

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1620

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1680

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1740

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1800

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1860

aucgcggugg ggcugcugcu cuacugcaag gcccggucca cccccguuac gcugagcaag     1920

gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  130
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  130
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu uaaccgcagu aacauucugu      300

uuugcauccg gccaaaacau aacagaagaa uuuuaccaau caacuugcuc ugcagucuca      360

aaagguuauc uaucugcauu aagaacaggc ugguacaccu caguaauaac gaucgaacua      420

ucaaacauca aagaaaacaa auguaaugga acagacgcaa aaguaaaacu aaucaaacaa      480

gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac uccucaugca aaguacacca      540

gcaacaaaua acagagcaag acgugaacua ccacguuuua ugaauuacac gcucaauaac      600

gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa gaagauuccu cggauuccua      660

cuaggcguag gcucagcaau agcuucagga guagcaguau caaaaguacu ccaccucgaa      720

ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa acaaagcagu uguuucacuc      780

ucaaacggag uaucaguacu aaccucaaaa guacuugacc uaaaaaauua uauagacaaa      840

caacuauuac caauaguaaa caaacaaagc ugcuccaucu ccaacaucga gacagucaua      900

gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca gagaauuuuc aguaaacgca      960

ggaguaacua ccccaguauc aacauauaug uuaacaaacu cagaacuccu aagucuaauc     1020

aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga gcaacaaugu acaaauaguu     1080

cgucaacaau cuuacuccau aaugucuaua auaaaagaag aaguacucgc cuauguaguc     1140

caacuaccac uauacggagu caucgauaca ccaugcugga aacuccacac auccccacuc     1200

uguacuacua acaccaaaga agguucaaau auaugccuaa ccagaacaga uagagguugg     1260

uacugcgaua augcaggauc aguauccuuu uucccccaag ccgaaacaug caaaguucaa     1320

uccaauagag uauuuuguga uacaaugaac ucuuuaaccc ucccauccga agucaaucua     1380

uguaacgucg acauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaacagac     1440

gucucauccu caguuauaac guccuuaggc gcuauaguau caugcuacgg caaaacaaaa     1500

uguacagcau caaacaaaaa cagaggaauc auaaaaacuu ucucuaacgg uugcgacuau     1560

guauccaaca aaggugucga cacaguaucc guaggcaaca cccuuuacua uguuaauaaa     1620

caagaaggaa aaucucuaua uguaaaaggc gaaccaauua uaaauuuuua cgacccccuu     1680

gucuuucccu cugacgaauu ugacgcuucc auaucacaag ucaacgaaaa aaucaaccaa     1740

ucccucgcau ucauacgcaa aucagacgaa cuacuacaua acgucaacgc aggcaaaucc     1800

acaacaaaca uaaugauaac cacaaucaua auuguaauaa uaguaauacu acuuucucua     1860

auagcagucg gauuacucuu auacuguaaa gcucgaucaa caccagucac ccucucuaaa     1920

gaucaacuau ccggaaucaa caacauagcu uucucaaacu aaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  131
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  131
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uacucaaagc caacgcaauc acaaccauac ucaccgccgu caccuucugc      300

uuugcaucug gccagaacau cacugaagag uucuaccaau ccacaugcuc cgccguaagc      360

aaaggcuacc uauccgcccu acgcaccggc ugguacacca gcguaaucac cauagaacuc      420

uccaauauaa aagaaaacaa augcaacggc accgacgcaa aagucaagcu aauaaaacaa      480

gaacucgaca aauacaaaaa cgccguuacc gaacuccagc uacucaugca aucgacccca      540

gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca ugaacuacac ccuaaacaac      600

gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac gccgcuuccu cggauuccuc      660

cucggcgucg gcuccgcaau cgccagcggc gucgccguua gcaaaguccu ucaccucgaa      720

ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa acaaggccgu aguaucccug      780

ucaaacggcg ucuccguccu uacauccaaa guccucgacc ucaagaacua cauagacaaa      840

cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua gcaacaucga aaccguaauc      900

gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc gcgaguucag cgucaacgcc      960

ggcguaacca ccccugucuc aacauacaug cuaaccaaca gcgaacugcu cucccucauc     1020

aacgacaugc ccaucaccaa cgaccaaaag aaacucauga gcaacaacgu acaaaucgug     1080

cgccaacagu ccuacucaau aaugucaauc aucaaagaag aagugcuagc auacgucgua     1140

caacuaccac ucuacggcgu aauagauacc cccugcugga agcuccauac cuccccacuc     1200

uguaccacca acaccaaaga aggcucaaac aucugccuaa cgcgcacaga ccguggaugg     1260

uacugugaca acgccggcuc cgucuccuuc uucccucaag ccgaaacaug caaaguccaa     1320

uccaacagag ucuucugcga uaccaugaac ucccugacac ucccaagcga agucaaccuu     1380

ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga ucaugacauc aaaaaccgac     1440

guauccuccu cuguaauaac cucccuaggc gcaaucguau caugcuacgg caaaaccaaa     1500

uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu ucucgaacgg cugcgacuac     1560

gucuccaaca aaggcguaga cacaguuucc guaggcaaca cccucuacua cgucaauaaa     1620

caggaaggca agucccucua cgucaaaggc gaacccauca ucaauuucua cgacccccuc     1680

guuuuccccu ccgaugaguu cgacgcaagc aucagccagg ucaacgaaaa gauaaaccag     1740

ucccucgccu ucauccgcaa aucagaugaa cuccuucaca acguuaacgc aggcaagagc     1800

accaccaaca ucaugaucac aacuauaauc aucgucauaa ucgucauccu acucucacua     1860

aucgccgucg gucuccuacu auauuguaaa gcccgaucaa caccggucac acucuccaaa     1920

gaccaacucu ccggaaucaa caauaucgcu uucucgaacu aaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  132
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  132
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      120

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      180

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      240

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      300

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      360

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      420

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      480

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      540

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      600

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      660

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      720

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      780

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc      840

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu      900

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua      960

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1020

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1080

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1140

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1200

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1260

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1320

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1380

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1440

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1500

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1560

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1620

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1680

auugcuguug gacugcucuu auacuguaag gccagaagca caccagucac acuaagcaaa     1740

gaucaacuga gugguauaaa uaauauugca uuuaguaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  133
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  133
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  134
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  134
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1140

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1560

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca cgcccgugac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  135
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  135
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  136
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  136
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      600

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      720

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      780

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug      900

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu      960

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1020

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1080

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1140

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1200

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1260

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1320

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1380

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1440

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1500

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1560

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1620

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1680

aucgcugugg gccugcuucu guacugcaag gccaggucaa cacccguuac guugagcaag     1740

gaccagcucu cugggauaaa caauaucgcu uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  137
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  137
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  138
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  138
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      600

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      720

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      780

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu      900

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug      960

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1020

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1080

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1140

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1200

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1260

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1320

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1380

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1440

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1500

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1560

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1680

aucgcggugg ggcugcugcu cuacugcaag gcccggucca cccccguuac gcugagcaag     1740

gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  139
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  139
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu uaaccgcagu aacauucugu      120

uuugcauccg gccaaaacau aacagaagaa uuuuaccaau caacuugcuc ugcagucuca      180

aaagguuauc uaucugcauu aagaacaggc ugguacaccu caguaauaac gaucgaacua      240

ucaaacauca aagaaaacaa auguaaugga acagacgcaa aaguaaaacu aaucaaacaa      300

gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac uccucaugca aaguacacca      360

gcaacaaaua acagagcaag acgugaacua ccacguuuua ugaauuacac gcucaauaac      420

gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa gaagauuccu cggauuccua      480

cuaggcguag gcucagcaau agcuucagga guagcaguau caaaaguacu ccaccucgaa      540

ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa acaaagcagu uguuucacuc      600

ucaaacggag uaucaguacu aaccucaaaa guacuugacc uaaaaaauua uauagacaaa      660

caacuauuac caauaguaaa caaacaaagc ugcuccaucu ccaacaucga gacagucaua      720

gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca gagaauuuuc aguaaacgca      780

ggaguaacua ccccaguauc aacauauaug uuaacaaacu cagaacuccu aagucuaauc      840

aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga gcaacaaugu acaaauaguu      900

cgucaacaau cuuacuccau aaugucuaua auaaaagaag aaguacucgc cuauguaguc      960

caacuaccac uauacggagu caucgauaca ccaugcugga aacuccacac auccccacuc     1020

uguacuacua acaccaaaga agguucaaau auaugccuaa ccagaacaga uagagguugg     1080

uacugcgaua augcaggauc aguauccuuu uucccccaag ccgaaacaug caaaguucaa     1140

uccaauagag uauuuuguga uacaaugaac ucuuuaaccc ucccauccga agucaaucua     1200

uguaacgucg acauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaacagac     1260

gucucauccu caguuauaac guccuuaggc gcuauaguau caugcuacgg caaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaauc auaaaaacuu ucucuaacgg uugcgacuau     1380

guauccaaca aaggugucga cacaguaucc guaggcaaca cccuuuacua uguuaauaaa     1440

caagaaggaa aaucucuaua uguaaaaggc gaaccaauua uaaauuuuua cgacccccuu     1500

gucuuucccu cugacgaauu ugacgcuucc auaucacaag ucaacgaaaa aaucaaccaa     1560

ucccucgcau ucauacgcaa aucagacgaa cuacuacaua acgucaacgc aggcaaaucc     1620

acaacaaaca uaaugauaac cacaaucaua auuguaauaa uaguaauacu acuuucucua     1680

auagcagucg gauuacucuu auacuguaaa gcucgaucaa caccagucac ccucucuaaa     1740

gaucaacuau ccggaaucaa caacauagcu uucucaaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  140
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  140
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uacucaaagc caacgcaauc acaaccauac ucaccgccgu caccuucugc      120

uuugcaucug gccagaacau cacugaagag uucuaccaau ccacaugcuc cgccguaagc      180

aaaggcuacc uauccgcccu acgcaccggc ugguacacca gcguaaucac cauagaacuc      240

uccaauauaa aagaaaacaa augcaacggc accgacgcaa aagucaagcu aauaaaacaa      300

gaacucgaca aauacaaaaa cgccguuacc gaacuccagc uacucaugca aucgacccca      360

gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca ugaacuacac ccuaaacaac      420

gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac gccgcuuccu cggauuccuc      480

cucggcgucg gcuccgcaau cgccagcggc gucgccguua gcaaaguccu ucaccucgaa      540

ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa acaaggccgu aguaucccug      600

ucaaacggcg ucuccguccu uacauccaaa guccucgacc ucaagaacua cauagacaaa      660

cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua gcaacaucga aaccguaauc      720

gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc gcgaguucag cgucaacgcc      780

ggcguaacca ccccugucuc aacauacaug cuaaccaaca gcgaacugcu cucccucauc      840

aacgacaugc ccaucaccaa cgaccaaaag aaacucauga gcaacaacgu acaaaucgug      900

cgccaacagu ccuacucaau aaugucaauc aucaaagaag aagugcuagc auacgucgua      960

caacuaccac ucuacggcgu aauagauacc cccugcugga agcuccauac cuccccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuaa cgcgcacaga ccguggaugg     1080

uacugugaca acgccggcuc cgucuccuuc uucccucaag ccgaaacaug caaaguccaa     1140

uccaacagag ucuucugcga uaccaugaac ucccugacac ucccaagcga agucaaccuu     1200

ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga ucaugacauc aaaaaccgac     1260

guauccuccu cuguaauaac cucccuaggc gcaaucguau caugcuacgg caaaaccaaa     1320

uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu ucucgaacgg cugcgacuac     1380

gucuccaaca aaggcguaga cacaguuucc guaggcaaca cccucuacua cgucaauaaa     1440

caggaaggca agucccucua cgucaaaggc gaacccauca ucaauuucua cgacccccuc     1500

guuuuccccu ccgaugaguu cgacgcaagc aucagccagg ucaacgaaaa gauaaaccag     1560

ucccucgccu ucauccgcaa aucagaugaa cuccuucaca acguuaacgc aggcaagagc     1620

accaccaaca ucaugaucac aacuauaauc aucgucauaa ucgucauccu acucucacua     1680

aucgccgucg gucuccuacu auauuguaaa gcccgaucaa caccggucac acucuccaaa     1740

gaccaacucu ccggaaucaa caauaucgcu uucucgaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  141
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  141
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagaagca     1740

caccagucac acuaagcaaa gaucaacuga gugguauaaa uaauauugca uuuaguaacu     1800

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  142
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  142
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  143
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca     1740

cgcccgugac ccuguccaag gaccagcuga gcggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  144
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  145
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  145
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggucaa     1740

cacccguuac guugagcaag gaccagcucu cugggauaaa caauaucgcu uucuccaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  146
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  146
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  147
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  147
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggucca     1740

cccccguuac gcugagcaag gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  148
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  148
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu      120

uaaccgcagu aacauucugu uuugcauccg gccaaaacau aacagaagaa uuuuaccaau      180

caacuugcuc ugcagucuca aaagguuauc uaucugcauu aagaacaggc ugguacaccu      240

caguaauaac gaucgaacua ucaaacauca aagaaaacaa auguaaugga acagacgcaa      300

aaguaaaacu aaucaaacaa gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac      360

uccucaugca aaguacacca gcaacaaaua acagagcaag acgugaacua ccacguuuua      420

ugaauuacac gcucaauaac gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa      480

gaagauuccu cggauuccua cuaggcguag gcucagcaau agcuucagga guagcaguau      540

caaaaguacu ccaccucgaa ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa      600

acaaagcagu uguuucacuc ucaaacggag uaucaguacu aaccucaaaa guacuugacc      660

uaaaaaauua uauagacaaa caacuauuac caauaguaaa caaacaaagc ugcuccaucu      720

ccaacaucga gacagucaua gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca      780

gagaauuuuc aguaaacgca ggaguaacua ccccaguauc aacauauaug uuaacaaacu      840

cagaacuccu aagucuaauc aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga      900

gcaacaaugu acaaauaguu cgucaacaau cuuacuccau aaugucuaua auaaaagaag      960

aaguacucgc cuauguaguc caacuaccac uauacggagu caucgauaca ccaugcugga     1020

aacuccacac auccccacuc uguacuacua acaccaaaga agguucaaau auaugccuaa     1080

ccagaacaga uagagguugg uacugcgaua augcaggauc aguauccuuu uucccccaag     1140

ccgaaacaug caaaguucaa uccaauagag uauuuuguga uacaaugaac ucuuuaaccc     1200

ucccauccga agucaaucua uguaacgucg acauauuuaa cccaaaauac gauugcaaaa     1260

uaaugacauc aaaaacagac gucucauccu caguuauaac guccuuaggc gcuauaguau     1320

caugcuacgg caaaacaaaa uguacagcau caaacaaaaa cagaggaauc auaaaaacuu     1380

ucucuaacgg uugcgacuau guauccaaca aaggugucga cacaguaucc guaggcaaca     1440

cccuuuacua uguuaauaaa caagaaggaa aaucucuaua uguaaaaggc gaaccaauua     1500

uaaauuuuua cgacccccuu gucuuucccu cugacgaauu ugacgcuucc auaucacaag     1560

ucaacgaaaa aaucaaccaa ucccucgcau ucauacgcaa aucagacgaa cuacuacaua     1620

acgucaacgc aggcaaaucc acaacaaaca uaaugauaac cacaaucaua auuguaauaa     1680

uaguaauacu acuuucucua auagcagucg gauuacucuu auacuguaaa gcucgaucaa     1740

caccagucac ccucucuaaa gaucaacuau ccggaaucaa caacauagcu uucucaaacu     1800

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  149
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  149
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uacucaaagc caacgcaauc acaaccauac      120

ucaccgccgu caccuucugc uuugcaucug gccagaacau cacugaagag uucuaccaau      180

ccacaugcuc cgccguaagc aaaggcuacc uauccgcccu acgcaccggc ugguacacca      240

gcguaaucac cauagaacuc uccaauauaa aagaaaacaa augcaacggc accgacgcaa      300

aagucaagcu aauaaaacaa gaacucgaca aauacaaaaa cgccguuacc gaacuccagc      360

uacucaugca aucgacccca gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca      420

ugaacuacac ccuaaacaac gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac      480

gccgcuuccu cggauuccuc cucggcgucg gcuccgcaau cgccagcggc gucgccguua      540

gcaaaguccu ucaccucgaa ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa      600

acaaggccgu aguaucccug ucaaacggcg ucuccguccu uacauccaaa guccucgacc      660

ucaagaacua cauagacaaa cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua      720

gcaacaucga aaccguaauc gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc      780

gcgaguucag cgucaacgcc ggcguaacca ccccugucuc aacauacaug cuaaccaaca      840

gcgaacugcu cucccucauc aacgacaugc ccaucaccaa cgaccaaaag aaacucauga      900

gcaacaacgu acaaaucgug cgccaacagu ccuacucaau aaugucaauc aucaaagaag      960

aagugcuagc auacgucgua caacuaccac ucuacggcgu aauagauacc cccugcugga     1020

agcuccauac cuccccacuc uguaccacca acaccaaaga aggcucaaac aucugccuaa     1080

cgcgcacaga ccguggaugg uacugugaca acgccggcuc cgucuccuuc uucccucaag     1140

ccgaaacaug caaaguccaa uccaacagag ucuucugcga uaccaugaac ucccugacac     1200

ucccaagcga agucaaccuu ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga     1260

ucaugacauc aaaaaccgac guauccuccu cuguaauaac cucccuaggc gcaaucguau     1320

caugcuacgg caaaaccaaa uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu     1380

ucucgaacgg cugcgacuac gucuccaaca aaggcguaga cacaguuucc guaggcaaca     1440

cccucuacua cgucaauaaa caggaaggca agucccucua cgucaaaggc gaacccauca     1500

ucaauuucua cgacccccuc guuuuccccu ccgaugaguu cgacgcaagc aucagccagg     1560

ucaacgaaaa gauaaaccag ucccucgccu ucauccgcaa aucagaugaa cuccuucaca     1620

acguuaacgc aggcaagagc accaccaaca ucaugaucac aacuauaauc aucgucauaa     1680

ucgucauccu acucucacua aucgccgucg gucuccuacu auauuguaaa gcccgaucaa     1740

caccggucac acucuccaaa gaccaacucu ccggaaucaa caauaucgcu uucucgaacu     1800

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  150
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  150
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagaagca     1740

caccagucac acuaagcaaa gaucaacuga gugguauaaa uaauauugca uuuaguaacu     1800

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  151
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  151
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  152
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  152
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca     1740

cgcccgugac ccuguccaag gaccagcuga gcggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  153
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  153
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  154
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  154
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggucaa     1740

cacccguuac guugagcaag gaccagcucu cugggauaaa caauaucgcu uucuccaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  155
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  155
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  156
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  156
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggucca     1740

cccccguuac gcugagcaag gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  157
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  157
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu      120

uaaccgcagu aacauucugu uuugcauccg gccaaaacau aacagaagaa uuuuaccaau      180

caacuugcuc ugcagucuca aaagguuauc uaucugcauu aagaacaggc ugguacaccu      240

caguaauaac gaucgaacua ucaaacauca aagaaaacaa auguaaugga acagacgcaa      300

aaguaaaacu aaucaaacaa gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac      360

uccucaugca aaguacacca gcaacaaaua acagagcaag acgugaacua ccacguuuua      420

ugaauuacac gcucaauaac gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa      480

gaagauuccu cggauuccua cuaggcguag gcucagcaau agcuucagga guagcaguau      540

caaaaguacu ccaccucgaa ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa      600

acaaagcagu uguuucacuc ucaaacggag uaucaguacu aaccucaaaa guacuugacc      660

uaaaaaauua uauagacaaa caacuauuac caauaguaaa caaacaaagc ugcuccaucu      720

ccaacaucga gacagucaua gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca      780

gagaauuuuc aguaaacgca ggaguaacua ccccaguauc aacauauaug uuaacaaacu      840

cagaacuccu aagucuaauc aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga      900

gcaacaaugu acaaauaguu cgucaacaau cuuacuccau aaugucuaua auaaaagaag      960

aaguacucgc cuauguaguc caacuaccac uauacggagu caucgauaca ccaugcugga     1020

aacuccacac auccccacuc uguacuacua acaccaaaga agguucaaau auaugccuaa     1080

ccagaacaga uagagguugg uacugcgaua augcaggauc aguauccuuu uucccccaag     1140

ccgaaacaug caaaguucaa uccaauagag uauuuuguga uacaaugaac ucuuuaaccc     1200

ucccauccga agucaaucua uguaacgucg acauauuuaa cccaaaauac gauugcaaaa     1260

uaaugacauc aaaaacagac gucucauccu caguuauaac guccuuaggc gcuauaguau     1320

caugcuacgg caaaacaaaa uguacagcau caaacaaaaa cagaggaauc auaaaaacuu     1380

ucucuaacgg uugcgacuau guauccaaca aaggugucga cacaguaucc guaggcaaca     1440

cccuuuacua uguuaauaaa caagaaggaa aaucucuaua uguaaaaggc gaaccaauua     1500

uaaauuuuua cgacccccuu gucuuucccu cugacgaauu ugacgcuucc auaucacaag     1560

ucaacgaaaa aaucaaccaa ucccucgcau ucauacgcaa aucagacgaa cuacuacaua     1620

acgucaacgc aggcaaaucc acaacaaaca uaaugauaac cacaaucaua auuguaauaa     1680

uaguaauacu acuuucucua auagcagucg gauuacucuu auacuguaaa gcucgaucaa     1740

caccagucac ccucucuaaa gaucaacuau ccggaaucaa caacauagcu uucucaaacu     1800

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  158
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  158
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uacucaaagc caacgcaauc acaaccauac      120

ucaccgccgu caccuucugc uuugcaucug gccagaacau cacugaagag uucuaccaau      180

ccacaugcuc cgccguaagc aaaggcuacc uauccgcccu acgcaccggc ugguacacca      240

gcguaaucac cauagaacuc uccaauauaa aagaaaacaa augcaacggc accgacgcaa      300

aagucaagcu aauaaaacaa gaacucgaca aauacaaaaa cgccguuacc gaacuccagc      360

uacucaugca aucgacccca gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca      420

ugaacuacac ccuaaacaac gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac      480

gccgcuuccu cggauuccuc cucggcgucg gcuccgcaau cgccagcggc gucgccguua      540

gcaaaguccu ucaccucgaa ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa      600

acaaggccgu aguaucccug ucaaacggcg ucuccguccu uacauccaaa guccucgacc      660

ucaagaacua cauagacaaa cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua      720

gcaacaucga aaccguaauc gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc      780

gcgaguucag cgucaacgcc ggcguaacca ccccugucuc aacauacaug cuaaccaaca      840

gcgaacugcu cucccucauc aacgacaugc ccaucaccaa cgaccaaaag aaacucauga      900

gcaacaacgu acaaaucgug cgccaacagu ccuacucaau aaugucaauc aucaaagaag      960

aagugcuagc auacgucgua caacuaccac ucuacggcgu aauagauacc cccugcugga     1020

agcuccauac cuccccacuc uguaccacca acaccaaaga aggcucaaac aucugccuaa     1080

cgcgcacaga ccguggaugg uacugugaca acgccggcuc cgucuccuuc uucccucaag     1140

ccgaaacaug caaaguccaa uccaacagag ucuucugcga uaccaugaac ucccugacac     1200

ucccaagcga agucaaccuu ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga     1260

ucaugacauc aaaaaccgac guauccuccu cuguaauaac cucccuaggc gcaaucguau     1320

caugcuacgg caaaaccaaa uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu     1380

ucucgaacgg cugcgacuac gucuccaaca aaggcguaga cacaguuucc guaggcaaca     1440

cccucuacua cgucaauaaa caggaaggca agucccucua cgucaaaggc gaacccauca     1500

ucaauuucua cgacccccuc guuuuccccu ccgaugaguu cgacgcaagc aucagccagg     1560

ucaacgaaaa gauaaaccag ucccucgccu ucauccgcaa aucagaugaa cuccuucaca     1620

acguuaacgc aggcaagagc accaccaaca ucaugaucac aacuauaauc aucgucauaa     1680

ucgucauccu acucucacua aucgccgucg gucuccuacu auauuguaaa gcccgaucaa     1740

caccggucac acucuccaaa gaccaacucu ccggaaucaa caauaucgcu uucucgaacu     1800

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  159
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  159
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gaagcacacc agucacacua     1800

agcaaagauc aacugagugg uauaaauaau auugcauuua guaacuaagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  160
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  160
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  161
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  161
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcagcacgcc cgugacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgccuucu ccaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  162
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  162
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  163
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  163
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggucaacacc cguuacguug     1800

agcaaggacc agcucucugg gauaaacaau aucgcuuucu ccaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  164
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  164
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  165
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  165
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc gguccacccc cguuacgcug     1800

agcaaggacc agcuuucugg aauuaacaau aucgcuuuca gcaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  166
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  166
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauauu aaaagcuaac gcaaucacua cuaucuuaac cgcaguaaca      180

uucuguuuug cauccggcca aaacauaaca gaagaauuuu accaaucaac uugcucugca      240

gucucaaaag guuaucuauc ugcauuaaga acaggcuggu acaccucagu aauaacgauc      300

gaacuaucaa acaucaaaga aaacaaaugu aauggaacag acgcaaaagu aaaacuaauc      360

aaacaagaac uagacaaaua caaaaacgca guaaccgaac uccaacuccu caugcaaagu      420

acaccagcaa caaauaacag agcaagacgu gaacuaccac guuuuaugaa uuacacgcuc      480

aauaacgcaa aaaaaacaaa uguuacccua ucaaaaaaac gaaaaagaag auuccucgga      540

uuccuacuag gcguaggcuc agcaauagcu ucaggaguag caguaucaaa aguacuccac      600

cucgaaggag aaguaaacaa aaucaaaagc gcucuccucu caacaaacaa agcaguuguu      660

ucacucucaa acggaguauc aguacuaacc ucaaaaguac uugaccuaaa aaauuauaua      720

gacaaacaac uauuaccaau aguaaacaaa caaagcugcu ccaucuccaa caucgagaca      780

gucauagaau uucaacaaaa aaauaaccgc cuauuagaaa uaaccagaga auuuucagua      840

aacgcaggag uaacuacccc aguaucaaca uauauguuaa caaacucaga acuccuaagu      900

cuaaucaacg acaugccaau aaccaacgac caaaaaaaac uaaugagcaa caauguacaa      960

auaguucguc aacaaucuua cuccauaaug ucuauaauaa aagaagaagu acucgccuau     1020

guaguccaac uaccacuaua cggagucauc gauacaccau gcuggaaacu ccacacaucc     1080

ccacucugua cuacuaacac caaagaaggu ucaaauauau gccuaaccag aacagauaga     1140

gguugguacu gcgauaaugc aggaucagua uccuuuuucc cccaagccga aacaugcaaa     1200

guucaaucca auagaguauu uugugauaca augaacucuu uaacccuccc auccgaaguc     1260

aaucuaugua acgucgacau auuuaaccca aaauacgauu gcaaaauaau gacaucaaaa     1320

acagacgucu cauccucagu uauaacgucc uuaggcgcua uaguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa caaaaacaga ggaaucauaa aaacuuucuc uaacgguugc     1440

gacuauguau ccaacaaagg ugucgacaca guauccguag gcaacacccu uuacuauguu     1500

aauaaacaag aaggaaaauc ucuauaugua aaaggcgaac caauuauaaa uuuuuacgac     1560

ccccuugucu uucccucuga cgaauuugac gcuuccauau cacaagucaa cgaaaaaauc     1620

aaccaauccc ucgcauucau acgcaaauca gacgaacuac uacauaacgu caacgcaggc     1680

aaauccacaa caaacauaau gauaaccaca aucauaauug uaauaauagu aauacuacuu     1740

ucucuaauag cagucggauu acucuuauac uguaaagcuc gaucaacacc agucacccuc     1800

ucuaaagauc aacuauccgg aaucaacaac auagcuuucu caaacuaagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  167
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  167
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauacu caaagccaac gcaaucacaa ccauacucac cgccgucacc      180

uucugcuuug caucuggcca gaacaucacu gaagaguucu accaauccac augcuccgcc      240

guaagcaaag gcuaccuauc cgcccuacgc accggcuggu acaccagcgu aaucaccaua      300

gaacucucca auauaaaaga aaacaaaugc aacggcaccg acgcaaaagu caagcuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc guuaccgaac uccagcuacu caugcaaucg      420

accccagcaa ccaacaaccg ugcgagacgc gaacuccccc gcuucaugaa cuacacccua      480

aacaacgcca aaaagaccaa cguaacucua uccaagaaac gcaaacgccg cuuccucgga      540

uuccuccucg gcgucggcuc cgcaaucgcc agcggcgucg ccguuagcaa aguccuucac      600

cucgaaggag aaguaaacaa aauuaaaagc gcccucuuau ccacaaacaa ggccguagua      660

ucccugucaa acggcgucuc cguccuuaca uccaaagucc ucgaccucaa gaacuacaua      720

gacaaacagc uacuacccau uguaaauaaa caaagcugcu caauuagcaa caucgaaacc      780

guaaucgagu uccagcagaa aaacaacaga cuucucgaaa ucacccgcga guucagcguc      840

aacgccggcg uaaccacccc ugucucaaca uacaugcuaa ccaacagcga acugcucucc      900

cucaucaacg acaugcccau caccaacgac caaaagaaac ucaugagcaa caacguacaa      960

aucgugcgcc aacaguccua cucaauaaug ucaaucauca aagaagaagu gcuagcauac     1020

gucguacaac uaccacucua cggcguaaua gauacccccu gcuggaagcu ccauaccucc     1080

ccacucugua ccaccaacac caaagaaggc ucaaacaucu gccuaacgcg cacagaccgu     1140

ggaugguacu gugacaacgc cggcuccguc uccuucuucc cucaagccga aacaugcaaa     1200

guccaaucca acagagucuu cugcgauacc augaacuccc ugacacuccc aagcgaaguc     1260

aaccuuugca acgucgauau cuuuaacccc aaauacgacu gcaagaucau gacaucaaaa     1320

accgacguau ccuccucugu aauaaccucc cuaggcgcaa ucguaucaug cuacggcaaa     1380

accaaaugua ccgccuccaa caaaaaucgc ggcaucauca aaaccuucuc gaacggcugc     1440

gacuacgucu ccaacaaagg cguagacaca guuuccguag gcaacacccu cuacuacguc     1500

aauaaacagg aaggcaaguc ccucuacguc aaaggcgaac ccaucaucaa uuucuacgac     1560

ccccucguuu uccccuccga ugaguucgac gcaagcauca gccaggucaa cgaaaagaua     1620

aaccaguccc ucgccuucau ccgcaaauca gaugaacucc uucacaacgu uaacgcaggc     1680

aagagcacca ccaacaucau gaucacaacu auaaucaucg ucauaaucgu cauccuacuc     1740

ucacuaaucg ccgucggucu ccuacuauau uguaaagccc gaucaacacc ggucacacuc     1800

uccaaagacc aacucuccgg aaucaacaau aucgcuuucu cgaacuaagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  168
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  168
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagaagcac accagucaca cuaagcaaag aucaacugag ugguauaaau     1800

aauauugcau uuaguaacua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  169
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  169
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  170
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  170
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcagcac gcccgugacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  171
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  171
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  172
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  172
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggucaac acccguuacg uugagcaagg accagcucuc ugggauaaac     1800

aauaucgcuu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  173
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  173
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  174
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  174
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccgguccac ccccguuacg cugagcaagg accagcuuuc uggaauuaac     1800

aauaucgcuu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  175
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  175
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau auuaaaagcu      120

aacgcaauca cuacuaucuu aaccgcagua acauucuguu uugcauccgg ccaaaacaua      180

acagaagaau uuuaccaauc aacuugcucu gcagucucaa aagguuaucu aucugcauua      240

agaacaggcu gguacaccuc aguaauaacg aucgaacuau caaacaucaa agaaaacaaa      300

uguaauggaa cagacgcaaa aguaaaacua aucaaacaag aacuagacaa auacaaaaac      360

gcaguaaccg aacuccaacu ccucaugcaa aguacaccag caacaaauaa cagagcaaga      420

cgugaacuac cacguuuuau gaauuacacg cucaauaacg caaaaaaaac aaauguuacc      480

cuaucaaaaa aacgaaaaag aagauuccuc ggauuccuac uaggcguagg cucagcaaua      540

gcuucaggag uagcaguauc aaaaguacuc caccucgaag gagaaguaaa caaaaucaaa      600

agcgcucucc ucucaacaaa caaagcaguu guuucacucu caaacggagu aucaguacua      660

accucaaaag uacuugaccu aaaaaauuau auagacaaac aacuauuacc aauaguaaac      720

aaacaaagcu gcuccaucuc caacaucgag acagucauag aauuucaaca aaaaaauaac      780

cgccuauuag aaauaaccag agaauuuuca guaaacgcag gaguaacuac cccaguauca      840

acauauaugu uaacaaacuc agaacuccua agucuaauca acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaaugag caacaaugua caaauaguuc gucaacaauc uuacuccaua      960

augucuauaa uaaaagaaga aguacucgcc uauguagucc aacuaccacu auacggaguc     1020

aucgauacac caugcuggaa acuccacaca uccccacucu guacuacuaa caccaaagaa     1080

gguucaaaua uaugccuaac cagaacagau agagguuggu acugcgauaa ugcaggauca     1140

guauccuuuu ucccccaagc cgaaacaugc aaaguucaau ccaauagagu auuuugugau     1200

acaaugaacu cuuuaacccu cccauccgaa gucaaucuau guaacgucga cauauuuaac     1260

ccaaaauacg auugcaaaau aaugacauca aaaacagacg ucucauccuc aguuauaacg     1320

uccuuaggcg cuauaguauc augcuacggc aaaacaaaau guacagcauc aaacaaaaac     1380

agaggaauca uaaaaacuuu cucuaacggu ugcgacuaug uauccaacaa aggugucgac     1440

acaguauccg uaggcaacac ccuuuacuau guuaauaaac aagaaggaaa aucucuauau     1500

guaaaaggcg aaccaauuau aaauuuuuac gacccccuug ucuuucccuc ugacgaauuu     1560

gacgcuucca uaucacaagu caacgaaaaa aucaaccaau cccucgcauu cauacgcaaa     1620

ucagacgaac uacuacauaa cgucaacgca ggcaaaucca caacaaacau aaugauaacc     1680

acaaucauaa uuguaauaau aguaauacua cuuucucuaa uagcagucgg auuacucuua     1740

uacuguaaag cucgaucaac accagucacc cucucuaaag aucaacuauc cggaaucaac     1800

aacauagcuu ucucaaacua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  176
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  176
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau acucaaagcc      120

aacgcaauca caaccauacu caccgccguc accuucugcu uugcaucugg ccagaacauc      180

acugaagagu ucuaccaauc cacaugcucc gccguaagca aaggcuaccu auccgcccua      240

cgcaccggcu gguacaccag cguaaucacc auagaacucu ccaauauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa agucaagcua auaaaacaag aacucgacaa auacaaaaac      360

gccguuaccg aacuccagcu acucaugcaa ucgaccccag caaccaacaa ccgugcgaga      420

cgcgaacucc cccgcuucau gaacuacacc cuaaacaacg ccaaaaagac caacguaacu      480

cuauccaaga aacgcaaacg ccgcuuccuc ggauuccucc ucggcgucgg cuccgcaauc      540

gccagcggcg ucgccguuag caaaguccuu caccucgaag gagaaguaaa caaaauuaaa      600

agcgcccucu uauccacaaa caaggccgua guaucccugu caaacggcgu cuccguccuu      660

acauccaaag uccucgaccu caagaacuac auagacaaac agcuacuacc cauuguaaau      720

aaacaaagcu gcucaauuag caacaucgaa accguaaucg aguuccagca gaaaaacaac      780

agacuucucg aaaucacccg cgaguucagc gucaacgccg gcguaaccac cccugucuca      840

acauacaugc uaaccaacag cgaacugcuc ucccucauca acgacaugcc caucaccaac      900

gaccaaaaga aacucaugag caacaacgua caaaucgugc gccaacaguc cuacucaaua      960

augucaauca ucaaagaaga agugcuagca uacgucguac aacuaccacu cuacggcgua     1020

auagauaccc ccugcuggaa gcuccauacc uccccacucu guaccaccaa caccaaagaa     1080

ggcucaaaca ucugccuaac gcgcacagac cguggauggu acugugacaa cgccggcucc     1140

gucuccuucu ucccucaagc cgaaacaugc aaaguccaau ccaacagagu cuucugcgau     1200

accaugaacu cccugacacu cccaagcgaa gucaaccuuu gcaacgucga uaucuuuaac     1260

cccaaauacg acugcaagau caugacauca aaaaccgacg uauccuccuc uguaauaacc     1320

ucccuaggcg caaucguauc augcuacggc aaaaccaaau guaccgccuc caacaaaaau     1380

cgcggcauca ucaaaaccuu cucgaacggc ugcgacuacg ucuccaacaa aggcguagac     1440

acaguuuccg uaggcaacac ccucuacuac gucaauaaac aggaaggcaa gucccucuac     1500

gucaaaggcg aacccaucau caauuucuac gacccccucg uuuuccccuc cgaugaguuc     1560

gacgcaagca ucagccaggu caacgaaaag auaaaccagu cccucgccuu cauccgcaaa     1620

ucagaugaac uccuucacaa cguuaacgca ggcaagagca ccaccaacau caugaucaca     1680

acuauaauca ucgucauaau cgucauccua cucucacuaa ucgccgucgg ucuccuacua     1740

uauuguaaag cccgaucaac accggucaca cucuccaaag accaacucuc cggaaucaac     1800

aauaucgcuu ucucgaacua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  177
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  177
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gaagcacacc agucacacua     1800

agcaaagauc aacugagugg uauaaauaau auugcauuua guaacuaagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  178
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  178
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  179
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  179
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcagcacgcc cgugacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgccuucu ccaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  180
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  180
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  181
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  181
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggucaacacc cguuacguug     1800

agcaaggacc agcucucugg gauaaacaau aucgcuuucu ccaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  182
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  182
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  183
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  183
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc gguccacccc cguuacgcug     1800

agcaaggacc agcuuucugg aauuaacaau aucgcuuuca gcaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  184
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  184
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauauu aaaagcuaac gcaaucacua cuaucuuaac cgcaguaaca      180

uucuguuuug cauccggcca aaacauaaca gaagaauuuu accaaucaac uugcucugca      240

gucucaaaag guuaucuauc ugcauuaaga acaggcuggu acaccucagu aauaacgauc      300

gaacuaucaa acaucaaaga aaacaaaugu aauggaacag acgcaaaagu aaaacuaauc      360

aaacaagaac uagacaaaua caaaaacgca guaaccgaac uccaacuccu caugcaaagu      420

acaccagcaa caaauaacag agcaagacgu gaacuaccac guuuuaugaa uuacacgcuc      480

aauaacgcaa aaaaaacaaa uguuacccua ucaaaaaaac gaaaaagaag auuccucgga      540

uuccuacuag gcguaggcuc agcaauagcu ucaggaguag caguaucaaa aguacuccac      600

cucgaaggag aaguaaacaa aaucaaaagc gcucuccucu caacaaacaa agcaguuguu      660

ucacucucaa acggaguauc aguacuaacc ucaaaaguac uugaccuaaa aaauuauaua      720

gacaaacaac uauuaccaau aguaaacaaa caaagcugcu ccaucuccaa caucgagaca      780

gucauagaau uucaacaaaa aaauaaccgc cuauuagaaa uaaccagaga auuuucagua      840

aacgcaggag uaacuacccc aguaucaaca uauauguuaa caaacucaga acuccuaagu      900

cuaaucaacg acaugccaau aaccaacgac caaaaaaaac uaaugagcaa caauguacaa      960

auaguucguc aacaaucuua cuccauaaug ucuauaauaa aagaagaagu acucgccuau     1020

guaguccaac uaccacuaua cggagucauc gauacaccau gcuggaaacu ccacacaucc     1080

ccacucugua cuacuaacac caaagaaggu ucaaauauau gccuaaccag aacagauaga     1140

gguugguacu gcgauaaugc aggaucagua uccuuuuucc cccaagccga aacaugcaaa     1200

guucaaucca auagaguauu uugugauaca augaacucuu uaacccuccc auccgaaguc     1260

aaucuaugua acgucgacau auuuaaccca aaauacgauu gcaaaauaau gacaucaaaa     1320

acagacgucu cauccucagu uauaacgucc uuaggcgcua uaguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa caaaaacaga ggaaucauaa aaacuuucuc uaacgguugc     1440

gacuauguau ccaacaaagg ugucgacaca guauccguag gcaacacccu uuacuauguu     1500

aauaaacaag aaggaaaauc ucuauaugua aaaggcgaac caauuauaaa uuuuuacgac     1560

ccccuugucu uucccucuga cgaauuugac gcuuccauau cacaagucaa cgaaaaaauc     1620

aaccaauccc ucgcauucau acgcaaauca gacgaacuac uacauaacgu caacgcaggc     1680

aaauccacaa caaacauaau gauaaccaca aucauaauug uaauaauagu aauacuacuu     1740

ucucuaauag cagucggauu acucuuauac uguaaagcuc gaucaacacc agucacccuc     1800

ucuaaagauc aacuauccgg aaucaacaac auagcuuucu caaacuaagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  185
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  185
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauacu caaagccaac gcaaucacaa ccauacucac cgccgucacc      180

uucugcuuug caucuggcca gaacaucacu gaagaguucu accaauccac augcuccgcc      240

guaagcaaag gcuaccuauc cgcccuacgc accggcuggu acaccagcgu aaucaccaua      300

gaacucucca auauaaaaga aaacaaaugc aacggcaccg acgcaaaagu caagcuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc guuaccgaac uccagcuacu caugcaaucg      420

accccagcaa ccaacaaccg ugcgagacgc gaacuccccc gcuucaugaa cuacacccua      480

aacaacgcca aaaagaccaa cguaacucua uccaagaaac gcaaacgccg cuuccucgga      540

uuccuccucg gcgucggcuc cgcaaucgcc agcggcgucg ccguuagcaa aguccuucac      600

cucgaaggag aaguaaacaa aauuaaaagc gcccucuuau ccacaaacaa ggccguagua      660

ucccugucaa acggcgucuc cguccuuaca uccaaagucc ucgaccucaa gaacuacaua      720

gacaaacagc uacuacccau uguaaauaaa caaagcugcu caauuagcaa caucgaaacc      780

guaaucgagu uccagcagaa aaacaacaga cuucucgaaa ucacccgcga guucagcguc      840

aacgccggcg uaaccacccc ugucucaaca uacaugcuaa ccaacagcga acugcucucc      900

cucaucaacg acaugcccau caccaacgac caaaagaaac ucaugagcaa caacguacaa      960

aucgugcgcc aacaguccua cucaauaaug ucaaucauca aagaagaagu gcuagcauac     1020

gucguacaac uaccacucua cggcguaaua gauacccccu gcuggaagcu ccauaccucc     1080

ccacucugua ccaccaacac caaagaaggc ucaaacaucu gccuaacgcg cacagaccgu     1140

ggaugguacu gugacaacgc cggcuccguc uccuucuucc cucaagccga aacaugcaaa     1200

guccaaucca acagagucuu cugcgauacc augaacuccc ugacacuccc aagcgaaguc     1260

aaccuuugca acgucgauau cuuuaacccc aaauacgacu gcaagaucau gacaucaaaa     1320

accgacguau ccuccucugu aauaaccucc cuaggcgcaa ucguaucaug cuacggcaaa     1380

accaaaugua ccgccuccaa caaaaaucgc ggcaucauca aaaccuucuc gaacggcugc     1440

gacuacgucu ccaacaaagg cguagacaca guuuccguag gcaacacccu cuacuacguc     1500

aauaaacagg aaggcaaguc ccucuacguc aaaggcgaac ccaucaucaa uuucuacgac     1560

ccccucguuu uccccuccga ugaguucgac gcaagcauca gccaggucaa cgaaaagaua     1620

aaccaguccc ucgccuucau ccgcaaauca gaugaacucc uucacaacgu uaacgcaggc     1680

aagagcacca ccaacaucau gaucacaacu auaaucaucg ucauaaucgu cauccuacuc     1740

ucacuaaucg ccgucggucu ccuacuauau uguaaagccc gaucaacacc ggucacacuc     1800

uccaaagacc aacucuccgg aaucaacaau aucgcuuucu cgaacuaagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  186
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  186
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagaagcac accagucaca cuaagcaaag aucaacugag ugguauaaau     1800

aauauugcau uuaguaacua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  187
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  187
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  188
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  188
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcagcac gcccgugacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  189
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  189
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  190
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  190
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggucaac acccguuacg uugagcaagg accagcucuc ugggauaaac     1800

aauaucgcuu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  191
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  191
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  192
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  192
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccgguccac ccccguuacg cugagcaagg accagcuuuc uggaauuaac     1800

aauaucgcuu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  193
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  193
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau auuaaaagcu      120

aacgcaauca cuacuaucuu aaccgcagua acauucuguu uugcauccgg ccaaaacaua      180

acagaagaau uuuaccaauc aacuugcucu gcagucucaa aagguuaucu aucugcauua      240

agaacaggcu gguacaccuc aguaauaacg aucgaacuau caaacaucaa agaaaacaaa      300

uguaauggaa cagacgcaaa aguaaaacua aucaaacaag aacuagacaa auacaaaaac      360

gcaguaaccg aacuccaacu ccucaugcaa aguacaccag caacaaauaa cagagcaaga      420

cgugaacuac cacguuuuau gaauuacacg cucaauaacg caaaaaaaac aaauguuacc      480

cuaucaaaaa aacgaaaaag aagauuccuc ggauuccuac uaggcguagg cucagcaaua      540

gcuucaggag uagcaguauc aaaaguacuc caccucgaag gagaaguaaa caaaaucaaa      600

agcgcucucc ucucaacaaa caaagcaguu guuucacucu caaacggagu aucaguacua      660

accucaaaag uacuugaccu aaaaaauuau auagacaaac aacuauuacc aauaguaaac      720

aaacaaagcu gcuccaucuc caacaucgag acagucauag aauuucaaca aaaaaauaac      780

cgccuauuag aaauaaccag agaauuuuca guaaacgcag gaguaacuac cccaguauca      840

acauauaugu uaacaaacuc agaacuccua agucuaauca acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaaugag caacaaugua caaauaguuc gucaacaauc uuacuccaua      960

augucuauaa uaaaagaaga aguacucgcc uauguagucc aacuaccacu auacggaguc     1020

aucgauacac caugcuggaa acuccacaca uccccacucu guacuacuaa caccaaagaa     1080

gguucaaaua uaugccuaac cagaacagau agagguuggu acugcgauaa ugcaggauca     1140

guauccuuuu ucccccaagc cgaaacaugc aaaguucaau ccaauagagu auuuugugau     1200

acaaugaacu cuuuaacccu cccauccgaa gucaaucuau guaacgucga cauauuuaac     1260

ccaaaauacg auugcaaaau aaugacauca aaaacagacg ucucauccuc aguuauaacg     1320

uccuuaggcg cuauaguauc augcuacggc aaaacaaaau guacagcauc aaacaaaaac     1380

agaggaauca uaaaaacuuu cucuaacggu ugcgacuaug uauccaacaa aggugucgac     1440

acaguauccg uaggcaacac ccuuuacuau guuaauaaac aagaaggaaa aucucuauau     1500

guaaaaggcg aaccaauuau aaauuuuuac gacccccuug ucuuucccuc ugacgaauuu     1560

gacgcuucca uaucacaagu caacgaaaaa aucaaccaau cccucgcauu cauacgcaaa     1620

ucagacgaac uacuacauaa cgucaacgca ggcaaaucca caacaaacau aaugauaacc     1680

acaaucauaa uuguaauaau aguaauacua cuuucucuaa uagcagucgg auuacucuua     1740

uacuguaaag cucgaucaac accagucacc cucucuaaag aucaacuauc cggaaucaac     1800

aacauagcuu ucucaaacua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  194
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  194
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau acucaaagcc      120

aacgcaauca caaccauacu caccgccguc accuucugcu uugcaucugg ccagaacauc      180

acugaagagu ucuaccaauc cacaugcucc gccguaagca aaggcuaccu auccgcccua      240

cgcaccggcu gguacaccag cguaaucacc auagaacucu ccaauauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa agucaagcua auaaaacaag aacucgacaa auacaaaaac      360

gccguuaccg aacuccagcu acucaugcaa ucgaccccag caaccaacaa ccgugcgaga      420

cgcgaacucc cccgcuucau gaacuacacc cuaaacaacg ccaaaaagac caacguaacu      480

cuauccaaga aacgcaaacg ccgcuuccuc ggauuccucc ucggcgucgg cuccgcaauc      540

gccagcggcg ucgccguuag caaaguccuu caccucgaag gagaaguaaa caaaauuaaa      600

agcgcccucu uauccacaaa caaggccgua guaucccugu caaacggcgu cuccguccuu      660

acauccaaag uccucgaccu caagaacuac auagacaaac agcuacuacc cauuguaaau      720

aaacaaagcu gcucaauuag caacaucgaa accguaaucg aguuccagca gaaaaacaac      780

agacuucucg aaaucacccg cgaguucagc gucaacgccg gcguaaccac cccugucuca      840

acauacaugc uaaccaacag cgaacugcuc ucccucauca acgacaugcc caucaccaac      900

gaccaaaaga aacucaugag caacaacgua caaaucgugc gccaacaguc cuacucaaua      960

augucaauca ucaaagaaga agugcuagca uacgucguac aacuaccacu cuacggcgua     1020

auagauaccc ccugcuggaa gcuccauacc uccccacucu guaccaccaa caccaaagaa     1080

ggcucaaaca ucugccuaac gcgcacagac cguggauggu acugugacaa cgccggcucc     1140

gucuccuucu ucccucaagc cgaaacaugc aaaguccaau ccaacagagu cuucugcgau     1200

accaugaacu cccugacacu cccaagcgaa gucaaccuuu gcaacgucga uaucuuuaac     1260

cccaaauacg acugcaagau caugacauca aaaaccgacg uauccuccuc uguaauaacc     1320

ucccuaggcg caaucguauc augcuacggc aaaaccaaau guaccgccuc caacaaaaau     1380

cgcggcauca ucaaaaccuu cucgaacggc ugcgacuacg ucuccaacaa aggcguagac     1440

acaguuuccg uaggcaacac ccucuacuac gucaauaaac aggaaggcaa gucccucuac     1500

gucaaaggcg aacccaucau caauuucuac gacccccucg uuuuccccuc cgaugaguuc     1560

gacgcaagca ucagccaggu caacgaaaag auaaaccagu cccucgccuu cauccgcaaa     1620

ucagaugaac uccuucacaa cguuaacgca ggcaagagca ccaccaacau caugaucaca     1680

acuauaauca ucgucauaau cgucauccua cucucacuaa ucgccgucgg ucuccuacua     1740

uauuguaaag cccgaucaac accggucaca cucuccaaag accaacucuc cggaaucaac     1800

aauaucgcuu ucucgaacua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  195
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  195
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagaagcac accagucaca cuaagcaaag aucaacugag ugguauaaau     1800

aauauugcau uuaguaacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  196
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  196
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  197
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  197
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcagcac gcccgugacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  198
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  198
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  199
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  199
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggucaac acccguuacg uugagcaagg accagcucuc ugggauaaac     1800

aauaucgcuu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  200
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  200
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  201
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  201
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccgguccac ccccguuacg cugagcaagg accagcuuuc uggaauuaac     1800

aauaucgcuu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  202
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  202
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau auuaaaagcu      120

aacgcaauca cuacuaucuu aaccgcagua acauucuguu uugcauccgg ccaaaacaua      180

acagaagaau uuuaccaauc aacuugcucu gcagucucaa aagguuaucu aucugcauua      240

agaacaggcu gguacaccuc aguaauaacg aucgaacuau caaacaucaa agaaaacaaa      300

uguaauggaa cagacgcaaa aguaaaacua aucaaacaag aacuagacaa auacaaaaac      360

gcaguaaccg aacuccaacu ccucaugcaa aguacaccag caacaaauaa cagagcaaga      420

cgugaacuac cacguuuuau gaauuacacg cucaauaacg caaaaaaaac aaauguuacc      480

cuaucaaaaa aacgaaaaag aagauuccuc ggauuccuac uaggcguagg cucagcaaua      540

gcuucaggag uagcaguauc aaaaguacuc caccucgaag gagaaguaaa caaaaucaaa      600

agcgcucucc ucucaacaaa caaagcaguu guuucacucu caaacggagu aucaguacua      660

accucaaaag uacuugaccu aaaaaauuau auagacaaac aacuauuacc aauaguaaac      720

aaacaaagcu gcuccaucuc caacaucgag acagucauag aauuucaaca aaaaaauaac      780

cgccuauuag aaauaaccag agaauuuuca guaaacgcag gaguaacuac cccaguauca      840

acauauaugu uaacaaacuc agaacuccua agucuaauca acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaaugag caacaaugua caaauaguuc gucaacaauc uuacuccaua      960

augucuauaa uaaaagaaga aguacucgcc uauguagucc aacuaccacu auacggaguc     1020

aucgauacac caugcuggaa acuccacaca uccccacucu guacuacuaa caccaaagaa     1080

gguucaaaua uaugccuaac cagaacagau agagguuggu acugcgauaa ugcaggauca     1140

guauccuuuu ucccccaagc cgaaacaugc aaaguucaau ccaauagagu auuuugugau     1200

acaaugaacu cuuuaacccu cccauccgaa gucaaucuau guaacgucga cauauuuaac     1260

ccaaaauacg auugcaaaau aaugacauca aaaacagacg ucucauccuc aguuauaacg     1320

uccuuaggcg cuauaguauc augcuacggc aaaacaaaau guacagcauc aaacaaaaac     1380

agaggaauca uaaaaacuuu cucuaacggu ugcgacuaug uauccaacaa aggugucgac     1440

acaguauccg uaggcaacac ccuuuacuau guuaauaaac aagaaggaaa aucucuauau     1500

guaaaaggcg aaccaauuau aaauuuuuac gacccccuug ucuuucccuc ugacgaauuu     1560

gacgcuucca uaucacaagu caacgaaaaa aucaaccaau cccucgcauu cauacgcaaa     1620

ucagacgaac uacuacauaa cgucaacgca ggcaaaucca caacaaacau aaugauaacc     1680

acaaucauaa uuguaauaau aguaauacua cuuucucuaa uagcagucgg auuacucuua     1740

uacuguaaag cucgaucaac accagucacc cucucuaaag aucaacuauc cggaaucaac     1800

aacauagcuu ucucaaacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  203
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  203
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau acucaaagcc      120

aacgcaauca caaccauacu caccgccguc accuucugcu uugcaucugg ccagaacauc      180

acugaagagu ucuaccaauc cacaugcucc gccguaagca aaggcuaccu auccgcccua      240

cgcaccggcu gguacaccag cguaaucacc auagaacucu ccaauauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa agucaagcua auaaaacaag aacucgacaa auacaaaaac      360

gccguuaccg aacuccagcu acucaugcaa ucgaccccag caaccaacaa ccgugcgaga      420

cgcgaacucc cccgcuucau gaacuacacc cuaaacaacg ccaaaaagac caacguaacu      480

cuauccaaga aacgcaaacg ccgcuuccuc ggauuccucc ucggcgucgg cuccgcaauc      540

gccagcggcg ucgccguuag caaaguccuu caccucgaag gagaaguaaa caaaauuaaa      600

agcgcccucu uauccacaaa caaggccgua guaucccugu caaacggcgu cuccguccuu      660

acauccaaag uccucgaccu caagaacuac auagacaaac agcuacuacc cauuguaaau      720

aaacaaagcu gcucaauuag caacaucgaa accguaaucg aguuccagca gaaaaacaac      780

agacuucucg aaaucacccg cgaguucagc gucaacgccg gcguaaccac cccugucuca      840

acauacaugc uaaccaacag cgaacugcuc ucccucauca acgacaugcc caucaccaac      900

gaccaaaaga aacucaugag caacaacgua caaaucgugc gccaacaguc cuacucaaua      960

augucaauca ucaaagaaga agugcuagca uacgucguac aacuaccacu cuacggcgua     1020

auagauaccc ccugcuggaa gcuccauacc uccccacucu guaccaccaa caccaaagaa     1080

ggcucaaaca ucugccuaac gcgcacagac cguggauggu acugugacaa cgccggcucc     1140

gucuccuucu ucccucaagc cgaaacaugc aaaguccaau ccaacagagu cuucugcgau     1200

accaugaacu cccugacacu cccaagcgaa gucaaccuuu gcaacgucga uaucuuuaac     1260

cccaaauacg acugcaagau caugacauca aaaaccgacg uauccuccuc uguaauaacc     1320

ucccuaggcg caaucguauc augcuacggc aaaaccaaau guaccgccuc caacaaaaau     1380

cgcggcauca ucaaaaccuu cucgaacggc ugcgacuacg ucuccaacaa aggcguagac     1440

acaguuuccg uaggcaacac ccucuacuac gucaauaaac aggaaggcaa gucccucuac     1500

gucaaaggcg aacccaucau caauuucuac gacccccucg uuuuccccuc cgaugaguuc     1560

gacgcaagca ucagccaggu caacgaaaag auaaaccagu cccucgccuu cauccgcaaa     1620

ucagaugaac uccuucacaa cguuaacgca ggcaagagca ccaccaacau caugaucaca     1680

acuauaauca ucgucauaau cgucauccua cucucacuaa ucgccgucgg ucuccuacua     1740

uauuguaaag cccgaucaac accggucaca cucuccaaag accaacucuc cggaaucaac     1800

aauaucgcuu ucucgaacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  204
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  204
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagaa gcacaccagu cacacuaagc aaagaucaac ugagugguau aaauaauauu     1800

gcauuuagua acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  205
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  205
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  206
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  206
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgca gcacgcccgu gacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gccuucucca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  207
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  207
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  208
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  208
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu caacacccgu uacguugagc aaggaccagc ucucugggau aaacaauauc     1800

gcuuucucca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  209
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  209
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  210
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  210
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu ccacccccgu uacgcugagc aaggaccagc uuucuggaau uaacaauauc     1800

gcuuucagca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  211
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  211
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauauuaaa agcuaacgca      120

aucacuacua ucuuaaccgc aguaacauuc uguuuugcau ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaacuug cucugcaguc ucaaaagguu aucuaucugc auuaagaaca      240

ggcugguaca ccucaguaau aacgaucgaa cuaucaaaca ucaaagaaaa caaauguaau      300

ggaacagacg caaaaguaaa acuaaucaaa caagaacuag acaaauacaa aaacgcagua      360

accgaacucc aacuccucau gcaaaguaca ccagcaacaa auaacagagc aagacgugaa      420

cuaccacguu uuaugaauua cacgcucaau aacgcaaaaa aaacaaaugu uacccuauca      480

aaaaaacgaa aaagaagauu ccucggauuc cuacuaggcg uaggcucagc aauagcuuca      540

ggaguagcag uaucaaaagu acuccaccuc gaaggagaag uaaacaaaau caaaagcgcu      600

cuccucucaa caaacaaagc aguuguuuca cucucaaacg gaguaucagu acuaaccuca      660

aaaguacuug accuaaaaaa uuauauagac aaacaacuau uaccaauagu aaacaaacaa      720

agcugcucca ucuccaacau cgagacaguc auagaauuuc aacaaaaaaa uaaccgccua      780

uuagaaauaa ccagagaauu uucaguaaac gcaggaguaa cuaccccagu aucaacauau      840

auguuaacaa acucagaacu ccuaagucua aucaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugagcaacaa uguacaaaua guucgucaac aaucuuacuc cauaaugucu      960

auaauaaaag aagaaguacu cgccuaugua guccaacuac cacuauacgg agucaucgau     1020

acaccaugcu ggaaacucca cacaucccca cucuguacua cuaacaccaa agaagguuca     1080

aauauaugcc uaaccagaac agauagaggu ugguacugcg auaaugcagg aucaguaucc     1140

uuuuuccccc aagccgaaac augcaaaguu caauccaaua gaguauuuug ugauacaaug     1200

aacucuuuaa cccucccauc cgaagucaau cuauguaacg ucgacauauu uaacccaaaa     1260

uacgauugca aaauaaugac aucaaaaaca gacgucucau ccucaguuau aacguccuua     1320

ggcgcuauag uaucaugcua cggcaaaaca aaauguacag caucaaacaa aaacagagga     1380

aucauaaaaa cuuucucuaa cgguugcgac uauguaucca acaaaggugu cgacacagua     1440

uccguaggca acacccuuua cuauguuaau aaacaagaag gaaaaucucu auauguaaaa     1500

ggcgaaccaa uuauaaauuu uuacgacccc cuugucuuuc ccucugacga auuugacgcu     1560

uccauaucac aagucaacga aaaaaucaac caaucccucg cauucauacg caaaucagac     1620

gaacuacuac auaacgucaa cgcaggcaaa uccacaacaa acauaaugau aaccacaauc     1680

auaauuguaa uaauaguaau acuacuuucu cuaauagcag ucggauuacu cuuauacugu     1740

aaagcucgau caacaccagu cacccucucu aaagaucaac uauccggaau caacaacaua     1800

gcuuucucaa acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  212
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  212
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauacucaa agccaacgca      120

aucacaacca uacucaccgc cgucaccuuc ugcuuugcau cuggccagaa caucacugaa      180

gaguucuacc aauccacaug cuccgccgua agcaaaggcu accuauccgc ccuacgcacc      240

ggcugguaca ccagcguaau caccauagaa cucuccaaua uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaagucaa gcuaauaaaa caagaacucg acaaauacaa aaacgccguu      360

accgaacucc agcuacucau gcaaucgacc ccagcaacca acaaccgugc gagacgcgaa      420

cucccccgcu ucaugaacua cacccuaaac aacgccaaaa agaccaacgu aacucuaucc      480

aagaaacgca aacgccgcuu ccucggauuc cuccucggcg ucggcuccgc aaucgccagc      540

ggcgucgccg uuagcaaagu ccuucaccuc gaaggagaag uaaacaaaau uaaaagcgcc      600

cucuuaucca caaacaaggc cguaguaucc cugucaaacg gcgucuccgu ccuuacaucc      660

aaaguccucg accucaagaa cuacauagac aaacagcuac uacccauugu aaauaaacaa      720

agcugcucaa uuagcaacau cgaaaccgua aucgaguucc agcagaaaaa caacagacuu      780

cucgaaauca cccgcgaguu cagcgucaac gccggcguaa ccaccccugu cucaacauac      840

augcuaacca acagcgaacu gcucucccuc aucaacgaca ugcccaucac caacgaccaa      900

aagaaacuca ugagcaacaa cguacaaauc gugcgccaac aguccuacuc aauaauguca      960

aucaucaaag aagaagugcu agcauacguc guacaacuac cacucuacgg cguaauagau     1020

acccccugcu ggaagcucca uaccucccca cucuguacca ccaacaccaa agaaggcuca     1080

aacaucugcc uaacgcgcac agaccgugga ugguacugug acaacgccgg cuccgucucc     1140

uucuucccuc aagccgaaac augcaaaguc caauccaaca gagucuucug cgauaccaug     1200

aacucccuga cacucccaag cgaagucaac cuuugcaacg ucgauaucuu uaaccccaaa     1260

uacgacugca agaucaugac aucaaaaacc gacguauccu ccucuguaau aaccucccua     1320

ggcgcaaucg uaucaugcua cggcaaaacc aaauguaccg ccuccaacaa aaaucgcggc     1380

aucaucaaaa ccuucucgaa cggcugcgac uacgucucca acaaaggcgu agacacaguu     1440

uccguaggca acacccucua cuacgucaau aaacaggaag gcaagucccu cuacgucaaa     1500

ggcgaaccca ucaucaauuu cuacgacccc cucguuuucc ccuccgauga guucgacgca     1560

agcaucagcc aggucaacga aaagauaaac cagucccucg ccuucauccg caaaucagau     1620

gaacuccuuc acaacguuaa cgcaggcaag agcaccacca acaucaugau cacaacuaua     1680

aucaucguca uaaucgucau ccuacucuca cuaaucgccg ucggucuccu acuauauugu     1740

aaagcccgau caacaccggu cacacucucc aaagaccaac ucuccggaau caacaauauc     1800

gcuuucucga acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  213
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  213
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaag cacaccaguc acacuaagca aagaucaacu gagugguaua     1800

aauaauauug cauuuaguaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  214
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  214
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  215
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  215
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcag cacgcccgug acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  216
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  216
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  217
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  217
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccagguc aacacccguu acguugagca aggaccagcu cucugggaua     1800

aacaauaucg cuuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  218
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  218
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  219
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  219
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccgguc cacccccguu acgcugagca aggaccagcu uucuggaauu     1800

aacaauaucg cuuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  220
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  220
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauauuaaaa      120

gcuaacgcaa ucacuacuau cuuaaccgca guaacauucu guuuugcauc cggccaaaac      180

auaacagaag aauuuuacca aucaacuugc ucugcagucu caaaagguua ucuaucugca      240

uuaagaacag gcugguacac cucaguaaua acgaucgaac uaucaaacau caaagaaaac      300

aaauguaaug gaacagacgc aaaaguaaaa cuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguaa ccgaacucca acuccucaug caaaguacac cagcaacaaa uaacagagca      420

agacgugaac uaccacguuu uaugaauuac acgcucaaua acgcaaaaaa aacaaauguu      480

acccuaucaa aaaaacgaaa aagaagauuc cucggauucc uacuaggcgu aggcucagca      540

auagcuucag gaguagcagu aucaaaagua cuccaccucg aaggagaagu aaacaaaauc      600

aaaagcgcuc uccucucaac aaacaaagca guuguuucac ucucaaacgg aguaucagua      660

cuaaccucaa aaguacuuga ccuaaaaaau uauauagaca aacaacuauu accaauagua      720

aacaaacaaa gcugcuccau cuccaacauc gagacaguca uagaauuuca acaaaaaaau      780

aaccgccuau uagaaauaac cagagaauuu ucaguaaacg caggaguaac uaccccagua      840

ucaacauaua uguuaacaaa cucagaacuc cuaagucuaa ucaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gagcaacaau guacaaauag uucgucaaca aucuuacucc      960

auaaugucua uaauaaaaga agaaguacuc gccuauguag uccaacuacc acuauacgga     1020

gucaucgaua caccaugcug gaaacuccac acauccccac ucuguacuac uaacaccaaa     1080

gaagguucaa auauaugccu aaccagaaca gauagagguu gguacugcga uaaugcagga     1140

ucaguauccu uuuuccccca agccgaaaca ugcaaaguuc aauccaauag aguauuuugu     1200

gauacaauga acucuuuaac ccucccaucc gaagucaauc uauguaacgu cgacauauuu     1260

aacccaaaau acgauugcaa aauaaugaca ucaaaaacag acgucucauc cucaguuaua     1320

acguccuuag gcgcuauagu aucaugcuac ggcaaaacaa aauguacagc aucaaacaaa     1380

aacagaggaa ucauaaaaac uuucucuaac gguugcgacu auguauccaa caaagguguc     1440

gacacaguau ccguaggcaa cacccuuuac uauguuaaua aacaagaagg aaaaucucua     1500

uauguaaaag gcgaaccaau uauaaauuuu uacgaccccc uugucuuucc cucugacgaa     1560

uuugacgcuu ccauaucaca agucaacgaa aaaaucaacc aaucccucgc auucauacgc     1620

aaaucagacg aacuacuaca uaacgucaac gcaggcaaau ccacaacaaa cauaaugaua     1680

accacaauca uaauuguaau aauaguaaua cuacuuucuc uaauagcagu cggauuacuc     1740

uuauacugua aagcucgauc aacaccaguc acccucucua aagaucaacu auccggaauc     1800

aacaacauag cuuucucaaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  221
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  221
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauacucaaa      120

gccaacgcaa ucacaaccau acucaccgcc gucaccuucu gcuuugcauc uggccagaac      180

aucacugaag aguucuacca auccacaugc uccgccguaa gcaaaggcua ccuauccgcc      240

cuacgcaccg gcugguacac cagcguaauc accauagaac ucuccaauau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaagucaag cuaauaaaac aagaacucga caaauacaaa      360

aacgccguua ccgaacucca gcuacucaug caaucgaccc cagcaaccaa caaccgugcg      420

agacgcgaac ucccccgcuu caugaacuac acccuaaaca acgccaaaaa gaccaacgua      480

acucuaucca agaaacgcaa acgccgcuuc cucggauucc uccucggcgu cggcuccgca      540

aucgccagcg gcgucgccgu uagcaaaguc cuucaccucg aaggagaagu aaacaaaauu      600

aaaagcgccc ucuuauccac aaacaaggcc guaguauccc ugucaaacgg cgucuccguc      660

cuuacaucca aaguccucga ccucaagaac uacauagaca aacagcuacu acccauugua      720

aauaaacaaa gcugcucaau uagcaacauc gaaaccguaa ucgaguucca gcagaaaaac      780

aacagacuuc ucgaaaucac ccgcgaguuc agcgucaacg ccggcguaac caccccuguc      840

ucaacauaca ugcuaaccaa cagcgaacug cucucccuca ucaacgacau gcccaucacc      900

aacgaccaaa agaaacucau gagcaacaac guacaaaucg ugcgccaaca guccuacuca      960

auaaugucaa ucaucaaaga agaagugcua gcauacgucg uacaacuacc acucuacggc     1020

guaauagaua cccccugcug gaagcuccau accuccccac ucuguaccac caacaccaaa     1080

gaaggcucaa acaucugccu aacgcgcaca gaccguggau gguacuguga caacgccggc     1140

uccgucuccu ucuucccuca agccgaaaca ugcaaagucc aauccaacag agucuucugc     1200

gauaccauga acucccugac acucccaagc gaagucaacc uuugcaacgu cgauaucuuu     1260

aaccccaaau acgacugcaa gaucaugaca ucaaaaaccg acguauccuc cucuguaaua     1320

accucccuag gcgcaaucgu aucaugcuac ggcaaaacca aauguaccgc cuccaacaaa     1380

aaucgcggca ucaucaaaac cuucucgaac ggcugcgacu acgucuccaa caaaggcgua     1440

gacacaguuu ccguaggcaa cacccucuac uacgucaaua aacaggaagg caagucccuc     1500

uacgucaaag gcgaacccau caucaauuuc uacgaccccc ucguuuuccc cuccgaugag     1560

uucgacgcaa gcaucagcca ggucaacgaa aagauaaacc agucccucgc cuucauccgc     1620

aaaucagaug aacuccuuca caacguuaac gcaggcaaga gcaccaccaa caucaugauc     1680

acaacuauaa ucaucgucau aaucgucauc cuacucucac uaaucgccgu cggucuccua     1740

cuauauugua aagcccgauc aacaccgguc acacucucca aagaccaacu cuccggaauc     1800

aacaauaucg cuuucucgaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  222
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  222
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagaa gcacaccagu cacacuaagc aaagaucaac ugagugguau aaauaauauu     1800

gcauuuagua acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  223
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  223
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  224
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  224
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgca gcacgcccgu gacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gccuucucca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  225
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  225
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  226
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  226
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu caacacccgu uacguugagc aaggaccagc ucucugggau aaacaauauc     1800

gcuuucucca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  227
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  227
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  228
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  228
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu ccacccccgu uacgcugagc aaggaccagc uuucuggaau uaacaauauc     1800

gcuuucagca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  229
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  229
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauauuaaa agcuaacgca      120

aucacuacua ucuuaaccgc aguaacauuc uguuuugcau ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaacuug cucugcaguc ucaaaagguu aucuaucugc auuaagaaca      240

ggcugguaca ccucaguaau aacgaucgaa cuaucaaaca ucaaagaaaa caaauguaau      300

ggaacagacg caaaaguaaa acuaaucaaa caagaacuag acaaauacaa aaacgcagua      360

accgaacucc aacuccucau gcaaaguaca ccagcaacaa auaacagagc aagacgugaa      420

cuaccacguu uuaugaauua cacgcucaau aacgcaaaaa aaacaaaugu uacccuauca      480

aaaaaacgaa aaagaagauu ccucggauuc cuacuaggcg uaggcucagc aauagcuuca      540

ggaguagcag uaucaaaagu acuccaccuc gaaggagaag uaaacaaaau caaaagcgcu      600

cuccucucaa caaacaaagc aguuguuuca cucucaaacg gaguaucagu acuaaccuca      660

aaaguacuug accuaaaaaa uuauauagac aaacaacuau uaccaauagu aaacaaacaa      720

agcugcucca ucuccaacau cgagacaguc auagaauuuc aacaaaaaaa uaaccgccua      780

uuagaaauaa ccagagaauu uucaguaaac gcaggaguaa cuaccccagu aucaacauau      840

auguuaacaa acucagaacu ccuaagucua aucaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugagcaacaa uguacaaaua guucgucaac aaucuuacuc cauaaugucu      960

auaauaaaag aagaaguacu cgccuaugua guccaacuac cacuauacgg agucaucgau     1020

acaccaugcu ggaaacucca cacaucccca cucuguacua cuaacaccaa agaagguuca     1080

aauauaugcc uaaccagaac agauagaggu ugguacugcg auaaugcagg aucaguaucc     1140

uuuuuccccc aagccgaaac augcaaaguu caauccaaua gaguauuuug ugauacaaug     1200

aacucuuuaa cccucccauc cgaagucaau cuauguaacg ucgacauauu uaacccaaaa     1260

uacgauugca aaauaaugac aucaaaaaca gacgucucau ccucaguuau aacguccuua     1320

ggcgcuauag uaucaugcua cggcaaaaca aaauguacag caucaaacaa aaacagagga     1380

aucauaaaaa cuuucucuaa cgguugcgac uauguaucca acaaaggugu cgacacagua     1440

uccguaggca acacccuuua cuauguuaau aaacaagaag gaaaaucucu auauguaaaa     1500

ggcgaaccaa uuauaaauuu uuacgacccc cuugucuuuc ccucugacga auuugacgcu     1560

uccauaucac aagucaacga aaaaaucaac caaucccucg cauucauacg caaaucagac     1620

gaacuacuac auaacgucaa cgcaggcaaa uccacaacaa acauaaugau aaccacaauc     1680

auaauuguaa uaauaguaau acuacuuucu cuaauagcag ucggauuacu cuuauacugu     1740

aaagcucgau caacaccagu cacccucucu aaagaucaac uauccggaau caacaacaua     1800

gcuuucucaa acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  230
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  230
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauacucaa agccaacgca      120

aucacaacca uacucaccgc cgucaccuuc ugcuuugcau cuggccagaa caucacugaa      180

gaguucuacc aauccacaug cuccgccgua agcaaaggcu accuauccgc ccuacgcacc      240

ggcugguaca ccagcguaau caccauagaa cucuccaaua uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaagucaa gcuaauaaaa caagaacucg acaaauacaa aaacgccguu      360

accgaacucc agcuacucau gcaaucgacc ccagcaacca acaaccgugc gagacgcgaa      420

cucccccgcu ucaugaacua cacccuaaac aacgccaaaa agaccaacgu aacucuaucc      480

aagaaacgca aacgccgcuu ccucggauuc cuccucggcg ucggcuccgc aaucgccagc      540

ggcgucgccg uuagcaaagu ccuucaccuc gaaggagaag uaaacaaaau uaaaagcgcc      600

cucuuaucca caaacaaggc cguaguaucc cugucaaacg gcgucuccgu ccuuacaucc      660

aaaguccucg accucaagaa cuacauagac aaacagcuac uacccauugu aaauaaacaa      720

agcugcucaa uuagcaacau cgaaaccgua aucgaguucc agcagaaaaa caacagacuu      780

cucgaaauca cccgcgaguu cagcgucaac gccggcguaa ccaccccugu cucaacauac      840

augcuaacca acagcgaacu gcucucccuc aucaacgaca ugcccaucac caacgaccaa      900

aagaaacuca ugagcaacaa cguacaaauc gugcgccaac aguccuacuc aauaauguca      960

aucaucaaag aagaagugcu agcauacguc guacaacuac cacucuacgg cguaauagau     1020

acccccugcu ggaagcucca uaccucccca cucuguacca ccaacaccaa agaaggcuca     1080

aacaucugcc uaacgcgcac agaccgugga ugguacugug acaacgccgg cuccgucucc     1140

uucuucccuc aagccgaaac augcaaaguc caauccaaca gagucuucug cgauaccaug     1200

aacucccuga cacucccaag cgaagucaac cuuugcaacg ucgauaucuu uaaccccaaa     1260

uacgacugca agaucaugac aucaaaaacc gacguauccu ccucuguaau aaccucccua     1320

ggcgcaaucg uaucaugcua cggcaaaacc aaauguaccg ccuccaacaa aaaucgcggc     1380

aucaucaaaa ccuucucgaa cggcugcgac uacgucucca acaaaggcgu agacacaguu     1440

uccguaggca acacccucua cuacgucaau aaacaggaag gcaagucccu cuacgucaaa     1500

ggcgaaccca ucaucaauuu cuacgacccc cucguuuucc ccuccgauga guucgacgca     1560

agcaucagcc aggucaacga aaagauaaac cagucccucg ccuucauccg caaaucagau     1620

gaacuccuuc acaacguuaa cgcaggcaag agcaccacca acaucaugau cacaacuaua     1680

aucaucguca uaaucgucau ccuacucuca cuaaucgccg ucggucuccu acuauauugu     1740

aaagcccgau caacaccggu cacacucucc aaagaccaac ucuccggaau caacaauauc     1800

gcuuucucga acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  231
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  231
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agaagcacac cagucacacu aagcaaagau     1860

caacugagug guauaaauaa uauugcauuu aguaacuaag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  232
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  232
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  233
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  233
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcagcacgc ccgugacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc uccaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  234
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  234
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  235
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  235
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggucaacac ccguuacguu gagcaaggac     1860

cagcucucug ggauaaacaa uaucgcuuuc uccaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  236
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  236
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  237
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  237
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cgguccaccc ccguuacgcu gagcaaggac     1860

cagcuuucug gaauuaacaa uaucgcuuuc agcaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  238
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  238
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauau uaaaagcuaa cgcaaucacu acuaucuuaa ccgcaguaac auucuguuuu      240

gcauccggcc aaaacauaac agaagaauuu uaccaaucaa cuugcucugc agucucaaaa      300

gguuaucuau cugcauuaag aacaggcugg uacaccucag uaauaacgau cgaacuauca      360

aacaucaaag aaaacaaaug uaauggaaca gacgcaaaag uaaaacuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguaaccgaa cuccaacucc ucaugcaaag uacaccagca      480

acaaauaaca gagcaagacg ugaacuacca cguuuuauga auuacacgcu caauaacgca      540

aaaaaaacaa auguuacccu aucaaaaaaa cgaaaaagaa gauuccucgg auuccuacua      600

ggcguaggcu cagcaauagc uucaggagua gcaguaucaa aaguacucca ccucgaagga      660

gaaguaaaca aaaucaaaag cgcucuccuc ucaacaaaca aagcaguugu uucacucuca      720

aacggaguau caguacuaac cucaaaagua cuugaccuaa aaaauuauau agacaaacaa      780

cuauuaccaa uaguaaacaa acaaagcugc uccaucucca acaucgagac agucauagaa      840

uuucaacaaa aaaauaaccg ccuauuagaa auaaccagag aauuuucagu aaacgcagga      900

guaacuaccc caguaucaac auauauguua acaaacucag aacuccuaag ucuaaucaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugagca acaauguaca aauaguucgu     1020

caacaaucuu acuccauaau gucuauaaua aaagaagaag uacucgccua uguaguccaa     1080

cuaccacuau acggagucau cgauacacca ugcuggaaac uccacacauc cccacucugu     1140

acuacuaaca ccaaagaagg uucaaauaua ugccuaacca gaacagauag agguugguac     1200

ugcgauaaug caggaucagu auccuuuuuc ccccaagccg aaacaugcaa aguucaaucc     1260

aauagaguau uuugugauac aaugaacucu uuaacccucc cauccgaagu caaucuaugu     1320

aacgucgaca uauuuaaccc aaaauacgau ugcaaaauaa ugacaucaaa aacagacguc     1380

ucauccucag uuauaacguc cuuaggcgcu auaguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa acaaaaacag aggaaucaua aaaacuuucu cuaacgguug cgacuaugua     1500

uccaacaaag gugucgacac aguauccgua ggcaacaccc uuuacuaugu uaauaaacaa     1560

gaaggaaaau cucuauaugu aaaaggcgaa ccaauuauaa auuuuuacga cccccuuguc     1620

uuucccucug acgaauuuga cgcuuccaua ucacaaguca acgaaaaaau caaccaaucc     1680

cucgcauuca uacgcaaauc agacgaacua cuacauaacg ucaacgcagg caaauccaca     1740

acaaacauaa ugauaaccac aaucauaauu guaauaauag uaauacuacu uucucuaaua     1800

gcagucggau uacucuuaua cuguaaagcu cgaucaacac cagucacccu cucuaaagau     1860

caacuauccg gaaucaacaa cauagcuuuc ucaaacuaag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  239
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  239
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucauac ucaaagccaa cgcaaucaca accauacuca ccgccgucac cuucugcuuu      240

gcaucuggcc agaacaucac ugaagaguuc uaccaaucca caugcuccgc cguaagcaaa      300

ggcuaccuau ccgcccuacg caccggcugg uacaccagcg uaaucaccau agaacucucc      360

aauauaaaag aaaacaaaug caacggcacc gacgcaaaag ucaagcuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cguuaccgaa cuccagcuac ucaugcaauc gaccccagca      480

accaacaacc gugcgagacg cgaacucccc cgcuucauga acuacacccu aaacaacgcc      540

aaaaagacca acguaacucu auccaagaaa cgcaaacgcc gcuuccucgg auuccuccuc      600

ggcgucggcu ccgcaaucgc cagcggcguc gccguuagca aaguccuuca ccucgaagga      660

gaaguaaaca aaauuaaaag cgcccucuua uccacaaaca aggccguagu aucccuguca      720

aacggcgucu ccguccuuac auccaaaguc cucgaccuca agaacuacau agacaaacag      780

cuacuaccca uuguaaauaa acaaagcugc ucaauuagca acaucgaaac cguaaucgag      840

uuccagcaga aaaacaacag acuucucgaa aucacccgcg aguucagcgu caacgccggc      900

guaaccaccc cugucucaac auacaugcua accaacagcg aacugcucuc ccucaucaac      960

gacaugccca ucaccaacga ccaaaagaaa cucaugagca acaacguaca aaucgugcgc     1020

caacaguccu acucaauaau gucaaucauc aaagaagaag ugcuagcaua cgucguacaa     1080

cuaccacucu acggcguaau agauaccccc ugcuggaagc uccauaccuc cccacucugu     1140

accaccaaca ccaaagaagg cucaaacauc ugccuaacgc gcacagaccg uggaugguac     1200

ugugacaacg ccggcuccgu cuccuucuuc ccucaagccg aaacaugcaa aguccaaucc     1260

aacagagucu ucugcgauac caugaacucc cugacacucc caagcgaagu caaccuuugc     1320

aacgucgaua ucuuuaaccc caaauacgac ugcaagauca ugacaucaaa aaccgacgua     1380

uccuccucug uaauaaccuc ccuaggcgca aucguaucau gcuacggcaa aaccaaaugu     1440

accgccucca acaaaaaucg cggcaucauc aaaaccuucu cgaacggcug cgacuacguc     1500

uccaacaaag gcguagacac aguuuccgua ggcaacaccc ucuacuacgu caauaaacag     1560

gaaggcaagu cccucuacgu caaaggcgaa cccaucauca auuucuacga cccccucguu     1620

uuccccuccg augaguucga cgcaagcauc agccagguca acgaaaagau aaaccagucc     1680

cucgccuuca uccgcaaauc agaugaacuc cuucacaacg uuaacgcagg caagagcacc     1740

accaacauca ugaucacaac uauaaucauc gucauaaucg ucauccuacu cucacuaauc     1800

gccgucgguc uccuacuaua uuguaaagcc cgaucaacac cggucacacu cuccaaagac     1860

caacucuccg gaaucaacaa uaucgcuuuc ucgaacuaag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  240
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  240
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagaagca     1740

caccagucac acuaagcaaa gaucaacuga gugguauaaa uaauauugca uuuaguaacu     1800

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  241
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  241
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  242
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  242
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca     1740

cgcccgugac ccuguccaag gaccagcuga gcggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  243
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  243
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  244
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  244
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggucaa     1740

cacccguuac guugagcaag gaccagcucu cugggauaaa caauaucgcu uucuccaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  245
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  245
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  246
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  246
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggucca     1740

cccccguuac gcugagcaag gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  247
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  247
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu      120

uaaccgcagu aacauucugu uuugcauccg gccaaaacau aacagaagaa uuuuaccaau      180

caacuugcuc ugcagucuca aaagguuauc uaucugcauu aagaacaggc ugguacaccu      240

caguaauaac gaucgaacua ucaaacauca aagaaaacaa auguaaugga acagacgcaa      300

aaguaaaacu aaucaaacaa gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac      360

uccucaugca aaguacacca gcaacaaaua acagagcaag acgugaacua ccacguuuua      420

ugaauuacac gcucaauaac gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa      480

gaagauuccu cggauuccua cuaggcguag gcucagcaau agcuucagga guagcaguau      540

caaaaguacu ccaccucgaa ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa      600

acaaagcagu uguuucacuc ucaaacggag uaucaguacu aaccucaaaa guacuugacc      660

uaaaaaauua uauagacaaa caacuauuac caauaguaaa caaacaaagc ugcuccaucu      720

ccaacaucga gacagucaua gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca      780

gagaauuuuc aguaaacgca ggaguaacua ccccaguauc aacauauaug uuaacaaacu      840

cagaacuccu aagucuaauc aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga      900

gcaacaaugu acaaauaguu cgucaacaau cuuacuccau aaugucuaua auaaaagaag      960

aaguacucgc cuauguaguc caacuaccac uauacggagu caucgauaca ccaugcugga     1020

aacuccacac auccccacuc uguacuacua acaccaaaga agguucaaau auaugccuaa     1080

ccagaacaga uagagguugg uacugcgaua augcaggauc aguauccuuu uucccccaag     1140

ccgaaacaug caaaguucaa uccaauagag uauuuuguga uacaaugaac ucuuuaaccc     1200

ucccauccga agucaaucua uguaacgucg acauauuuaa cccaaaauac gauugcaaaa     1260

uaaugacauc aaaaacagac gucucauccu caguuauaac guccuuaggc gcuauaguau     1320

caugcuacgg caaaacaaaa uguacagcau caaacaaaaa cagaggaauc auaaaaacuu     1380

ucucuaacgg uugcgacuau guauccaaca aaggugucga cacaguaucc guaggcaaca     1440

cccuuuacua uguuaauaaa caagaaggaa aaucucuaua uguaaaaggc gaaccaauua     1500

uaaauuuuua cgacccccuu gucuuucccu cugacgaauu ugacgcuucc auaucacaag     1560

ucaacgaaaa aaucaaccaa ucccucgcau ucauacgcaa aucagacgaa cuacuacaua     1620

acgucaacgc aggcaaaucc acaacaaaca uaaugauaac cacaaucaua auuguaauaa     1680

uaguaauacu acuuucucua auagcagucg gauuacucuu auacuguaaa gcucgaucaa     1740

caccagucac ccucucuaaa gaucaacuau ccggaaucaa caacauagcu uucucaaacu     1800

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  248
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  248
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uacucaaagc caacgcaauc acaaccauac      120

ucaccgccgu caccuucugc uuugcaucug gccagaacau cacugaagag uucuaccaau      180

ccacaugcuc cgccguaagc aaaggcuacc uauccgcccu acgcaccggc ugguacacca      240

gcguaaucac cauagaacuc uccaauauaa aagaaaacaa augcaacggc accgacgcaa      300

aagucaagcu aauaaaacaa gaacucgaca aauacaaaaa cgccguuacc gaacuccagc      360

uacucaugca aucgacccca gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca      420

ugaacuacac ccuaaacaac gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac      480

gccgcuuccu cggauuccuc cucggcgucg gcuccgcaau cgccagcggc gucgccguua      540

gcaaaguccu ucaccucgaa ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa      600

acaaggccgu aguaucccug ucaaacggcg ucuccguccu uacauccaaa guccucgacc      660

ucaagaacua cauagacaaa cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua      720

gcaacaucga aaccguaauc gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc      780

gcgaguucag cgucaacgcc ggcguaacca ccccugucuc aacauacaug cuaaccaaca      840

gcgaacugcu cucccucauc aacgacaugc ccaucaccaa cgaccaaaag aaacucauga      900

gcaacaacgu acaaaucgug cgccaacagu ccuacucaau aaugucaauc aucaaagaag      960

aagugcuagc auacgucgua caacuaccac ucuacggcgu aauagauacc cccugcugga     1020

agcuccauac cuccccacuc uguaccacca acaccaaaga aggcucaaac aucugccuaa     1080

cgcgcacaga ccguggaugg uacugugaca acgccggcuc cgucuccuuc uucccucaag     1140

ccgaaacaug caaaguccaa uccaacagag ucuucugcga uaccaugaac ucccugacac     1200

ucccaagcga agucaaccuu ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga     1260

ucaugacauc aaaaaccgac guauccuccu cuguaauaac cucccuaggc gcaaucguau     1320

caugcuacgg caaaaccaaa uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu     1380

ucucgaacgg cugcgacuac gucuccaaca aaggcguaga cacaguuucc guaggcaaca     1440

cccucuacua cgucaauaaa caggaaggca agucccucua cgucaaaggc gaacccauca     1500

ucaauuucua cgacccccuc guuuuccccu ccgaugaguu cgacgcaagc aucagccagg     1560

ucaacgaaaa gauaaaccag ucccucgccu ucauccgcaa aucagaugaa cuccuucaca     1620

acguuaacgc aggcaagagc accaccaaca ucaugaucac aacuauaauc aucgucauaa     1680

ucgucauccu acucucacua aucgccgucg gucuccuacu auauuguaaa gcccgaucaa     1740

caccggucac acucuccaaa gaccaacucu ccggaaucaa caauaucgcu uucucgaacu     1800

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  249
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  249
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agaagcacac cagucacacu aagcaaagau     1860

caacugagug guauaaauaa uauugcauuu aguaacuaag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  250
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  250
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  251
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  251
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcagcacgc ccgugacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc uccaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  252
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  252
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  253
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  253
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggucaacac ccguuacguu gagcaaggac     1860

cagcucucug ggauaaacaa uaucgcuuuc uccaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  254
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  254
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  255
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  255
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cgguccaccc ccguuacgcu gagcaaggac     1860

cagcuuucug gaauuaacaa uaucgcuuuc agcaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  256
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  256
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauau uaaaagcuaa cgcaaucacu acuaucuuaa ccgcaguaac auucuguuuu      240

gcauccggcc aaaacauaac agaagaauuu uaccaaucaa cuugcucugc agucucaaaa      300

gguuaucuau cugcauuaag aacaggcugg uacaccucag uaauaacgau cgaacuauca      360

aacaucaaag aaaacaaaug uaauggaaca gacgcaaaag uaaaacuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguaaccgaa cuccaacucc ucaugcaaag uacaccagca      480

acaaauaaca gagcaagacg ugaacuacca cguuuuauga auuacacgcu caauaacgca      540

aaaaaaacaa auguuacccu aucaaaaaaa cgaaaaagaa gauuccucgg auuccuacua      600

ggcguaggcu cagcaauagc uucaggagua gcaguaucaa aaguacucca ccucgaagga      660

gaaguaaaca aaaucaaaag cgcucuccuc ucaacaaaca aagcaguugu uucacucuca      720

aacggaguau caguacuaac cucaaaagua cuugaccuaa aaaauuauau agacaaacaa      780

cuauuaccaa uaguaaacaa acaaagcugc uccaucucca acaucgagac agucauagaa      840

uuucaacaaa aaaauaaccg ccuauuagaa auaaccagag aauuuucagu aaacgcagga      900

guaacuaccc caguaucaac auauauguua acaaacucag aacuccuaag ucuaaucaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugagca acaauguaca aauaguucgu     1020

caacaaucuu acuccauaau gucuauaaua aaagaagaag uacucgccua uguaguccaa     1080

cuaccacuau acggagucau cgauacacca ugcuggaaac uccacacauc cccacucugu     1140

acuacuaaca ccaaagaagg uucaaauaua ugccuaacca gaacagauag agguugguac     1200

ugcgauaaug caggaucagu auccuuuuuc ccccaagccg aaacaugcaa aguucaaucc     1260

aauagaguau uuugugauac aaugaacucu uuaacccucc cauccgaagu caaucuaugu     1320

aacgucgaca uauuuaaccc aaaauacgau ugcaaaauaa ugacaucaaa aacagacguc     1380

ucauccucag uuauaacguc cuuaggcgcu auaguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa acaaaaacag aggaaucaua aaaacuuucu cuaacgguug cgacuaugua     1500

uccaacaaag gugucgacac aguauccgua ggcaacaccc uuuacuaugu uaauaaacaa     1560

gaaggaaaau cucuauaugu aaaaggcgaa ccaauuauaa auuuuuacga cccccuuguc     1620

uuucccucug acgaauuuga cgcuuccaua ucacaaguca acgaaaaaau caaccaaucc     1680

cucgcauuca uacgcaaauc agacgaacua cuacauaacg ucaacgcagg caaauccaca     1740

acaaacauaa ugauaaccac aaucauaauu guaauaauag uaauacuacu uucucuaaua     1800

gcagucggau uacucuuaua cuguaaagcu cgaucaacac cagucacccu cucuaaagau     1860

caacuauccg gaaucaacaa cauagcuuuc ucaaacuaag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  257
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  257
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucauac ucaaagccaa cgcaaucaca accauacuca ccgccgucac cuucugcuuu      240

gcaucuggcc agaacaucac ugaagaguuc uaccaaucca caugcuccgc cguaagcaaa      300

ggcuaccuau ccgcccuacg caccggcugg uacaccagcg uaaucaccau agaacucucc      360

aauauaaaag aaaacaaaug caacggcacc gacgcaaaag ucaagcuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cguuaccgaa cuccagcuac ucaugcaauc gaccccagca      480

accaacaacc gugcgagacg cgaacucccc cgcuucauga acuacacccu aaacaacgcc      540

aaaaagacca acguaacucu auccaagaaa cgcaaacgcc gcuuccucgg auuccuccuc      600

ggcgucggcu ccgcaaucgc cagcggcguc gccguuagca aaguccuuca ccucgaagga      660

gaaguaaaca aaauuaaaag cgcccucuua uccacaaaca aggccguagu aucccuguca      720

aacggcgucu ccguccuuac auccaaaguc cucgaccuca agaacuacau agacaaacag      780

cuacuaccca uuguaaauaa acaaagcugc ucaauuagca acaucgaaac cguaaucgag      840

uuccagcaga aaaacaacag acuucucgaa aucacccgcg aguucagcgu caacgccggc      900

guaaccaccc cugucucaac auacaugcua accaacagcg aacugcucuc ccucaucaac      960

gacaugccca ucaccaacga ccaaaagaaa cucaugagca acaacguaca aaucgugcgc     1020

caacaguccu acucaauaau gucaaucauc aaagaagaag ugcuagcaua cgucguacaa     1080

cuaccacucu acggcguaau agauaccccc ugcuggaagc uccauaccuc cccacucugu     1140

accaccaaca ccaaagaagg cucaaacauc ugccuaacgc gcacagaccg uggaugguac     1200

ugugacaacg ccggcuccgu cuccuucuuc ccucaagccg aaacaugcaa aguccaaucc     1260

aacagagucu ucugcgauac caugaacucc cugacacucc caagcgaagu caaccuuugc     1320

aacgucgaua ucuuuaaccc caaauacgac ugcaagauca ugacaucaaa aaccgacgua     1380

uccuccucug uaauaaccuc ccuaggcgca aucguaucau gcuacggcaa aaccaaaugu     1440

accgccucca acaaaaaucg cggcaucauc aaaaccuucu cgaacggcug cgacuacguc     1500

uccaacaaag gcguagacac aguuuccgua ggcaacaccc ucuacuacgu caauaaacag     1560

gaaggcaagu cccucuacgu caaaggcgaa cccaucauca auuucuacga cccccucguu     1620

uuccccuccg augaguucga cgcaagcauc agccagguca acgaaaagau aaaccagucc     1680

cucgccuuca uccgcaaauc agaugaacuc cuucacaacg uuaacgcagg caagagcacc     1740

accaacauca ugaucacaac uauaaucauc gucauaaucg ucauccuacu cucacuaauc     1800

gccgucgguc uccuacuaua uuguaaagcc cgaucaacac cggucacacu cuccaaagac     1860

caacucuccg gaaucaacaa uaucgcuuuc ucgaacuaag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  258
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  258
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      180

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      240

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      300

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      360

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      420

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      480

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      540

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      600

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      660

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      720

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      780

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      840

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc      900

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu      960

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua     1020

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1080

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1140

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1200

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1260

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1320

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1380

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1440

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1500

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1560

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1620

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1680

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1740

auugcuguug gacugcucuu auacuguaag gccagaagca caccagucac acuaagcaaa     1800

gaucaacuga gugguauaaa uaauauugca uuuaguaacu aaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  259
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  259
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      540

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      600

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      660

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      780

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      840

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      900

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      960

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc     1020

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1080

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1140

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1200

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1380

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1500

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1560

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1680

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1740

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1800

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  260
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  260
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      540

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      600

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      660

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      780

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      840

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      960

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc     1020

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1080

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1140

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1200

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1260

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1380

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1500

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1560

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1620

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1680

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1740

aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca cgcccgugac ccuguccaag     1800

gaccagcuga gcggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  261
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  261
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      480

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      540

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      600

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      660

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      720

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      780

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      840

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      960

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc     1020

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1080

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1140

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1200

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1380

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1440

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1500

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1560

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1620

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1680

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1740

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1800

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  262
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  262
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      480

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      540

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      600

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      660

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      720

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      780

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      840

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc      900

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug      960

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu     1020

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1080

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1140

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1200

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1260

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1320

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1380

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1440

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1500

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1560

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1620

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1680

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1740

aucgcugugg gccugcuucu guacugcaag gccaggucaa cacccguuac guugagcaag     1800

gaccagcucu cugggauaaa caauaucgcu uucuccaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  263
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  263
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      480

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      540

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      600

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      660

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      720

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      780

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      840

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      960

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug     1020

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1080

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1140

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1200

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1260

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1320

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1380

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1500

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1560

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1680

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1740

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1800

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  264
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  264
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      480

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      540

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      600

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      660

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      720

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      780

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      840

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc      900

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu      960

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug     1020

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1080

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1140

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1200

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1260

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1320

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1380

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1440

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1500

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1560

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1620

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1680

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1740

aucgcggugg ggcugcugcu cuacugcaag gcccggucca cccccguuac gcugagcaag     1800

gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  265
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  265
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu uaaccgcagu aacauucugu      180

uuugcauccg gccaaaacau aacagaagaa uuuuaccaau caacuugcuc ugcagucuca      240

aaagguuauc uaucugcauu aagaacaggc ugguacaccu caguaauaac gaucgaacua      300

ucaaacauca aagaaaacaa auguaaugga acagacgcaa aaguaaaacu aaucaaacaa      360

gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac uccucaugca aaguacacca      420

gcaacaaaua acagagcaag acgugaacua ccacguuuua ugaauuacac gcucaauaac      480

gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa gaagauuccu cggauuccua      540

cuaggcguag gcucagcaau agcuucagga guagcaguau caaaaguacu ccaccucgaa      600

ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa acaaagcagu uguuucacuc      660

ucaaacggag uaucaguacu aaccucaaaa guacuugacc uaaaaaauua uauagacaaa      720

caacuauuac caauaguaaa caaacaaagc ugcuccaucu ccaacaucga gacagucaua      780

gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca gagaauuuuc aguaaacgca      840

ggaguaacua ccccaguauc aacauauaug uuaacaaacu cagaacuccu aagucuaauc      900

aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga gcaacaaugu acaaauaguu      960

cgucaacaau cuuacuccau aaugucuaua auaaaagaag aaguacucgc cuauguaguc     1020

caacuaccac uauacggagu caucgauaca ccaugcugga aacuccacac auccccacuc     1080

uguacuacua acaccaaaga agguucaaau auaugccuaa ccagaacaga uagagguugg     1140

uacugcgaua augcaggauc aguauccuuu uucccccaag ccgaaacaug caaaguucaa     1200

uccaauagag uauuuuguga uacaaugaac ucuuuaaccc ucccauccga agucaaucua     1260

uguaacgucg acauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaacagac     1320

gucucauccu caguuauaac guccuuaggc gcuauaguau caugcuacgg caaaacaaaa     1380

uguacagcau caaacaaaaa cagaggaauc auaaaaacuu ucucuaacgg uugcgacuau     1440

guauccaaca aaggugucga cacaguaucc guaggcaaca cccuuuacua uguuaauaaa     1500

caagaaggaa aaucucuaua uguaaaaggc gaaccaauua uaaauuuuua cgacccccuu     1560

gucuuucccu cugacgaauu ugacgcuucc auaucacaag ucaacgaaaa aaucaaccaa     1620

ucccucgcau ucauacgcaa aucagacgaa cuacuacaua acgucaacgc aggcaaaucc     1680

acaacaaaca uaaugauaac cacaaucaua auuguaauaa uaguaauacu acuuucucua     1740

auagcagucg gauuacucuu auacuguaaa gcucgaucaa caccagucac ccucucuaaa     1800

gaucaacuau ccggaaucaa caacauagcu uucucaaacu aaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  266
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  266
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uacucaaagc caacgcaauc acaaccauac ucaccgccgu caccuucugc      180

uuugcaucug gccagaacau cacugaagag uucuaccaau ccacaugcuc cgccguaagc      240

aaaggcuacc uauccgcccu acgcaccggc ugguacacca gcguaaucac cauagaacuc      300

uccaauauaa aagaaaacaa augcaacggc accgacgcaa aagucaagcu aauaaaacaa      360

gaacucgaca aauacaaaaa cgccguuacc gaacuccagc uacucaugca aucgacccca      420

gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca ugaacuacac ccuaaacaac      480

gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac gccgcuuccu cggauuccuc      540

cucggcgucg gcuccgcaau cgccagcggc gucgccguua gcaaaguccu ucaccucgaa      600

ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa acaaggccgu aguaucccug      660

ucaaacggcg ucuccguccu uacauccaaa guccucgacc ucaagaacua cauagacaaa      720

cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua gcaacaucga aaccguaauc      780

gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc gcgaguucag cgucaacgcc      840

ggcguaacca ccccugucuc aacauacaug cuaaccaaca gcgaacugcu cucccucauc      900

aacgacaugc ccaucaccaa cgaccaaaag aaacucauga gcaacaacgu acaaaucgug      960

cgccaacagu ccuacucaau aaugucaauc aucaaagaag aagugcuagc auacgucgua     1020

caacuaccac ucuacggcgu aauagauacc cccugcugga agcuccauac cuccccacuc     1080

uguaccacca acaccaaaga aggcucaaac aucugccuaa cgcgcacaga ccguggaugg     1140

uacugugaca acgccggcuc cgucuccuuc uucccucaag ccgaaacaug caaaguccaa     1200

uccaacagag ucuucugcga uaccaugaac ucccugacac ucccaagcga agucaaccuu     1260

ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga ucaugacauc aaaaaccgac     1320

guauccuccu cuguaauaac cucccuaggc gcaaucguau caugcuacgg caaaaccaaa     1380

uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu ucucgaacgg cugcgacuac     1440

gucuccaaca aaggcguaga cacaguuucc guaggcaaca cccucuacua cgucaauaaa     1500

caggaaggca agucccucua cgucaaaggc gaacccauca ucaauuucua cgacccccuc     1560

guuuuccccu ccgaugaguu cgacgcaagc aucagccagg ucaacgaaaa gauaaaccag     1620

ucccucgccu ucauccgcaa aucagaugaa cuccuucaca acguuaacgc aggcaagagc     1680

accaccaaca ucaugaucac aacuauaauc aucgucauaa ucgucauccu acucucacua     1740

aucgccgucg gucuccuacu auauuguaaa gcccgaucaa caccggucac acucuccaaa     1800

gaccaacucu ccggaaucaa caauaucgcu uucucgaacu aaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  267
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  267
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaag cacaccaguc acacuaagca aagaucaacu gagugguaua     1800

aauaauauug cauuuaguaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  268
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  268
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  269
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  269
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcag cacgcccgug acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  270
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  270
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  271
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  271
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccagguc aacacccguu acguugagca aggaccagcu cucugggaua     1800

aacaauaucg cuuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  272
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  272
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  273
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  273
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccgguc cacccccguu acgcugagca aggaccagcu uucuggaauu     1800

aacaauaucg cuuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  274
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  274
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauauuaaaa      120

gcuaacgcaa ucacuacuau cuuaaccgca guaacauucu guuuugcauc cggccaaaac      180

auaacagaag aauuuuacca aucaacuugc ucugcagucu caaaagguua ucuaucugca      240

uuaagaacag gcugguacac cucaguaaua acgaucgaac uaucaaacau caaagaaaac      300

aaauguaaug gaacagacgc aaaaguaaaa cuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguaa ccgaacucca acuccucaug caaaguacac cagcaacaaa uaacagagca      420

agacgugaac uaccacguuu uaugaauuac acgcucaaua acgcaaaaaa aacaaauguu      480

acccuaucaa aaaaacgaaa aagaagauuc cucggauucc uacuaggcgu aggcucagca      540

auagcuucag gaguagcagu aucaaaagua cuccaccucg aaggagaagu aaacaaaauc      600

aaaagcgcuc uccucucaac aaacaaagca guuguuucac ucucaaacgg aguaucagua      660

cuaaccucaa aaguacuuga ccuaaaaaau uauauagaca aacaacuauu accaauagua      720

aacaaacaaa gcugcuccau cuccaacauc gagacaguca uagaauuuca acaaaaaaau      780

aaccgccuau uagaaauaac cagagaauuu ucaguaaacg caggaguaac uaccccagua      840

ucaacauaua uguuaacaaa cucagaacuc cuaagucuaa ucaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gagcaacaau guacaaauag uucgucaaca aucuuacucc      960

auaaugucua uaauaaaaga agaaguacuc gccuauguag uccaacuacc acuauacgga     1020

gucaucgaua caccaugcug gaaacuccac acauccccac ucuguacuac uaacaccaaa     1080

gaagguucaa auauaugccu aaccagaaca gauagagguu gguacugcga uaaugcagga     1140

ucaguauccu uuuuccccca agccgaaaca ugcaaaguuc aauccaauag aguauuuugu     1200

gauacaauga acucuuuaac ccucccaucc gaagucaauc uauguaacgu cgacauauuu     1260

aacccaaaau acgauugcaa aauaaugaca ucaaaaacag acgucucauc cucaguuaua     1320

acguccuuag gcgcuauagu aucaugcuac ggcaaaacaa aauguacagc aucaaacaaa     1380

aacagaggaa ucauaaaaac uuucucuaac gguugcgacu auguauccaa caaagguguc     1440

gacacaguau ccguaggcaa cacccuuuac uauguuaaua aacaagaagg aaaaucucua     1500

uauguaaaag gcgaaccaau uauaaauuuu uacgaccccc uugucuuucc cucugacgaa     1560

uuugacgcuu ccauaucaca agucaacgaa aaaaucaacc aaucccucgc auucauacgc     1620

aaaucagacg aacuacuaca uaacgucaac gcaggcaaau ccacaacaaa cauaaugaua     1680

accacaauca uaauuguaau aauaguaaua cuacuuucuc uaauagcagu cggauuacuc     1740

uuauacugua aagcucgauc aacaccaguc acccucucua aagaucaacu auccggaauc     1800

aacaacauag cuuucucaaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  275
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  275
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauacucaaa      120

gccaacgcaa ucacaaccau acucaccgcc gucaccuucu gcuuugcauc uggccagaac      180

aucacugaag aguucuacca auccacaugc uccgccguaa gcaaaggcua ccuauccgcc      240

cuacgcaccg gcugguacac cagcguaauc accauagaac ucuccaauau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaagucaag cuaauaaaac aagaacucga caaauacaaa      360

aacgccguua ccgaacucca gcuacucaug caaucgaccc cagcaaccaa caaccgugcg      420

agacgcgaac ucccccgcuu caugaacuac acccuaaaca acgccaaaaa gaccaacgua      480

acucuaucca agaaacgcaa acgccgcuuc cucggauucc uccucggcgu cggcuccgca      540

aucgccagcg gcgucgccgu uagcaaaguc cuucaccucg aaggagaagu aaacaaaauu      600

aaaagcgccc ucuuauccac aaacaaggcc guaguauccc ugucaaacgg cgucuccguc      660

cuuacaucca aaguccucga ccucaagaac uacauagaca aacagcuacu acccauugua      720

aauaaacaaa gcugcucaau uagcaacauc gaaaccguaa ucgaguucca gcagaaaaac      780

aacagacuuc ucgaaaucac ccgcgaguuc agcgucaacg ccggcguaac caccccuguc      840

ucaacauaca ugcuaaccaa cagcgaacug cucucccuca ucaacgacau gcccaucacc      900

aacgaccaaa agaaacucau gagcaacaac guacaaaucg ugcgccaaca guccuacuca      960

auaaugucaa ucaucaaaga agaagugcua gcauacgucg uacaacuacc acucuacggc     1020

guaauagaua cccccugcug gaagcuccau accuccccac ucuguaccac caacaccaaa     1080

gaaggcucaa acaucugccu aacgcgcaca gaccguggau gguacuguga caacgccggc     1140

uccgucuccu ucuucccuca agccgaaaca ugcaaagucc aauccaacag agucuucugc     1200

gauaccauga acucccugac acucccaagc gaagucaacc uuugcaacgu cgauaucuuu     1260

aaccccaaau acgacugcaa gaucaugaca ucaaaaaccg acguauccuc cucuguaaua     1320

accucccuag gcgcaaucgu aucaugcuac ggcaaaacca aauguaccgc cuccaacaaa     1380

aaucgcggca ucaucaaaac cuucucgaac ggcugcgacu acgucuccaa caaaggcgua     1440

gacacaguuu ccguaggcaa cacccucuac uacgucaaua aacaggaagg caagucccuc     1500

uacgucaaag gcgaacccau caucaauuuc uacgaccccc ucguuuuccc cuccgaugag     1560

uucgacgcaa gcaucagcca ggucaacgaa aagauaaacc agucccucgc cuucauccgc     1620

aaaucagaug aacuccuuca caacguuaac gcaggcaaga gcaccaccaa caucaugauc     1680

acaacuauaa ucaucgucau aaucgucauc cuacucucac uaaucgccgu cggucuccua     1740

cuauauugua aagcccgauc aacaccgguc acacucucca aagaccaacu cuccggaauc     1800

aacaauaucg cuuucucgaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  276
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  276
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaag cacaccaguc     1740

acacuaagca aagaucaacu gagugguaua aauaauauug cauuuaguaa cuaaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  277
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  277
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  278
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  278
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcag cacgcccgug     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  279
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  279
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  280
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  280
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccagguc aacacccguu     1740

acguugagca aggaccagcu cucugggaua aacaauaucg cuuucuccaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  281
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  281
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  282
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  282
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccgguc cacccccguu     1740

acgcugagca aggaccagcu uucuggaauu aacaauaucg cuuucagcaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  283
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  283
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauauuaaaa gcuaacgcaa ucacuacuau cuuaaccgca      120

guaacauucu guuuugcauc cggccaaaac auaacagaag aauuuuacca aucaacuugc      180

ucugcagucu caaaagguua ucuaucugca uuaagaacag gcugguacac cucaguaaua      240

acgaucgaac uaucaaacau caaagaaaac aaauguaaug gaacagacgc aaaaguaaaa      300

cuaaucaaac aagaacuaga caaauacaaa aacgcaguaa ccgaacucca acuccucaug      360

caaaguacac cagcaacaaa uaacagagca agacgugaac uaccacguuu uaugaauuac      420

acgcucaaua acgcaaaaaa aacaaauguu acccuaucaa aaaaacgaaa aagaagauuc      480

cucggauucc uacuaggcgu aggcucagca auagcuucag gaguagcagu aucaaaagua      540

cuccaccucg aaggagaagu aaacaaaauc aaaagcgcuc uccucucaac aaacaaagca      600

guuguuucac ucucaaacgg aguaucagua cuaaccucaa aaguacuuga ccuaaaaaau      660

uauauagaca aacaacuauu accaauagua aacaaacaaa gcugcuccau cuccaacauc      720

gagacaguca uagaauuuca acaaaaaaau aaccgccuau uagaaauaac cagagaauuu      780

ucaguaaacg caggaguaac uaccccagua ucaacauaua uguuaacaaa cucagaacuc      840

cuaagucuaa ucaacgacau gccaauaacc aacgaccaaa aaaaacuaau gagcaacaau      900

guacaaauag uucgucaaca aucuuacucc auaaugucua uaauaaaaga agaaguacuc      960

gccuauguag uccaacuacc acuauacgga gucaucgaua caccaugcug gaaacuccac     1020

acauccccac ucuguacuac uaacaccaaa gaagguucaa auauaugccu aaccagaaca     1080

gauagagguu gguacugcga uaaugcagga ucaguauccu uuuuccccca agccgaaaca     1140

ugcaaaguuc aauccaauag aguauuuugu gauacaauga acucuuuaac ccucccaucc     1200

gaagucaauc uauguaacgu cgacauauuu aacccaaaau acgauugcaa aauaaugaca     1260

ucaaaaacag acgucucauc cucaguuaua acguccuuag gcgcuauagu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaacaaa aacagaggaa ucauaaaaac uuucucuaac     1380

gguugcgacu auguauccaa caaagguguc gacacaguau ccguaggcaa cacccuuuac     1440

uauguuaaua aacaagaagg aaaaucucua uauguaaaag gcgaaccaau uauaaauuuu     1500

uacgaccccc uugucuuucc cucugacgaa uuugacgcuu ccauaucaca agucaacgaa     1560

aaaaucaacc aaucccucgc auucauacgc aaaucagacg aacuacuaca uaacgucaac     1620

gcaggcaaau ccacaacaaa cauaaugaua accacaauca uaauuguaau aauaguaaua     1680

cuacuuucuc uaauagcagu cggauuacuc uuauacugua aagcucgauc aacaccaguc     1740

acccucucua aagaucaacu auccggaauc aacaacauag cuuucucaaa cuaaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  284
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  284
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauacucaaa gccaacgcaa ucacaaccau acucaccgcc      120

gucaccuucu gcuuugcauc uggccagaac aucacugaag aguucuacca auccacaugc      180

uccgccguaa gcaaaggcua ccuauccgcc cuacgcaccg gcugguacac cagcguaauc      240

accauagaac ucuccaauau aaaagaaaac aaaugcaacg gcaccgacgc aaaagucaag      300

cuaauaaaac aagaacucga caaauacaaa aacgccguua ccgaacucca gcuacucaug      360

caaucgaccc cagcaaccaa caaccgugcg agacgcgaac ucccccgcuu caugaacuac      420

acccuaaaca acgccaaaaa gaccaacgua acucuaucca agaaacgcaa acgccgcuuc      480

cucggauucc uccucggcgu cggcuccgca aucgccagcg gcgucgccgu uagcaaaguc      540

cuucaccucg aaggagaagu aaacaaaauu aaaagcgccc ucuuauccac aaacaaggcc      600

guaguauccc ugucaaacgg cgucuccguc cuuacaucca aaguccucga ccucaagaac      660

uacauagaca aacagcuacu acccauugua aauaaacaaa gcugcucaau uagcaacauc      720

gaaaccguaa ucgaguucca gcagaaaaac aacagacuuc ucgaaaucac ccgcgaguuc      780

agcgucaacg ccggcguaac caccccuguc ucaacauaca ugcuaaccaa cagcgaacug      840

cucucccuca ucaacgacau gcccaucacc aacgaccaaa agaaacucau gagcaacaac      900

guacaaaucg ugcgccaaca guccuacuca auaaugucaa ucaucaaaga agaagugcua      960

gcauacgucg uacaacuacc acucuacggc guaauagaua cccccugcug gaagcuccau     1020

accuccccac ucuguaccac caacaccaaa gaaggcucaa acaucugccu aacgcgcaca     1080

gaccguggau gguacuguga caacgccggc uccgucuccu ucuucccuca agccgaaaca     1140

ugcaaagucc aauccaacag agucuucugc gauaccauga acucccugac acucccaagc     1200

gaagucaacc uuugcaacgu cgauaucuuu aaccccaaau acgacugcaa gaucaugaca     1260

ucaaaaaccg acguauccuc cucuguaaua accucccuag gcgcaaucgu aucaugcuac     1320

ggcaaaacca aauguaccgc cuccaacaaa aaucgcggca ucaucaaaac cuucucgaac     1380

ggcugcgacu acgucuccaa caaaggcgua gacacaguuu ccguaggcaa cacccucuac     1440

uacgucaaua aacaggaagg caagucccuc uacgucaaag gcgaacccau caucaauuuc     1500

uacgaccccc ucguuuuccc cuccgaugag uucgacgcaa gcaucagcca ggucaacgaa     1560

aagauaaacc agucccucgc cuucauccgc aaaucagaug aacuccuuca caacguuaac     1620

gcaggcaaga gcaccaccaa caucaugauc acaacuauaa ucaucgucau aaucgucauc     1680

cuacucucac uaaucgccgu cggucuccua cuauauugua aagcccgauc aacaccgguc     1740

acacucucca aagaccaacu cuccggaauc aacaauaucg cuuucucgaa cuaaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  285
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  285
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gaagcacacc agucacacua     1800

agcaaagauc aacugagugg uauaaauaau auugcauuua guaacuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  286
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  286
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  287
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  287
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcagcacgcc cgugacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  288
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  288
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  289
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  289
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggucaacacc cguuacguug     1800

agcaaggacc agcucucugg gauaaacaau aucgcuuucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  290
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  290
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  291
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  291
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc gguccacccc cguuacgcug     1800

agcaaggacc agcuuucugg aauuaacaau aucgcuuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  292
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  292
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauauu aaaagcuaac gcaaucacua cuaucuuaac cgcaguaaca      180

uucuguuuug cauccggcca aaacauaaca gaagaauuuu accaaucaac uugcucugca      240

gucucaaaag guuaucuauc ugcauuaaga acaggcuggu acaccucagu aauaacgauc      300

gaacuaucaa acaucaaaga aaacaaaugu aauggaacag acgcaaaagu aaaacuaauc      360

aaacaagaac uagacaaaua caaaaacgca guaaccgaac uccaacuccu caugcaaagu      420

acaccagcaa caaauaacag agcaagacgu gaacuaccac guuuuaugaa uuacacgcuc      480

aauaacgcaa aaaaaacaaa uguuacccua ucaaaaaaac gaaaaagaag auuccucgga      540

uuccuacuag gcguaggcuc agcaauagcu ucaggaguag caguaucaaa aguacuccac      600

cucgaaggag aaguaaacaa aaucaaaagc gcucuccucu caacaaacaa agcaguuguu      660

ucacucucaa acggaguauc aguacuaacc ucaaaaguac uugaccuaaa aaauuauaua      720

gacaaacaac uauuaccaau aguaaacaaa caaagcugcu ccaucuccaa caucgagaca      780

gucauagaau uucaacaaaa aaauaaccgc cuauuagaaa uaaccagaga auuuucagua      840

aacgcaggag uaacuacccc aguaucaaca uauauguuaa caaacucaga acuccuaagu      900

cuaaucaacg acaugccaau aaccaacgac caaaaaaaac uaaugagcaa caauguacaa      960

auaguucguc aacaaucuua cuccauaaug ucuauaauaa aagaagaagu acucgccuau     1020

guaguccaac uaccacuaua cggagucauc gauacaccau gcuggaaacu ccacacaucc     1080

ccacucugua cuacuaacac caaagaaggu ucaaauauau gccuaaccag aacagauaga     1140

gguugguacu gcgauaaugc aggaucagua uccuuuuucc cccaagccga aacaugcaaa     1200

guucaaucca auagaguauu uugugauaca augaacucuu uaacccuccc auccgaaguc     1260

aaucuaugua acgucgacau auuuaaccca aaauacgauu gcaaaauaau gacaucaaaa     1320

acagacgucu cauccucagu uauaacgucc uuaggcgcua uaguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa caaaaacaga ggaaucauaa aaacuuucuc uaacgguugc     1440

gacuauguau ccaacaaagg ugucgacaca guauccguag gcaacacccu uuacuauguu     1500

aauaaacaag aaggaaaauc ucuauaugua aaaggcgaac caauuauaaa uuuuuacgac     1560

ccccuugucu uucccucuga cgaauuugac gcuuccauau cacaagucaa cgaaaaaauc     1620

aaccaauccc ucgcauucau acgcaaauca gacgaacuac uacauaacgu caacgcaggc     1680

aaauccacaa caaacauaau gauaaccaca aucauaauug uaauaauagu aauacuacuu     1740

ucucuaauag cagucggauu acucuuauac uguaaagcuc gaucaacacc agucacccuc     1800

ucuaaagauc aacuauccgg aaucaacaac auagcuuucu caaacuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  293
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  293
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauacu caaagccaac gcaaucacaa ccauacucac cgccgucacc      180

uucugcuuug caucuggcca gaacaucacu gaagaguucu accaauccac augcuccgcc      240

guaagcaaag gcuaccuauc cgcccuacgc accggcuggu acaccagcgu aaucaccaua      300

gaacucucca auauaaaaga aaacaaaugc aacggcaccg acgcaaaagu caagcuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc guuaccgaac uccagcuacu caugcaaucg      420

accccagcaa ccaacaaccg ugcgagacgc gaacuccccc gcuucaugaa cuacacccua      480

aacaacgcca aaaagaccaa cguaacucua uccaagaaac gcaaacgccg cuuccucgga      540

uuccuccucg gcgucggcuc cgcaaucgcc agcggcgucg ccguuagcaa aguccuucac      600

cucgaaggag aaguaaacaa aauuaaaagc gcccucuuau ccacaaacaa ggccguagua      660

ucccugucaa acggcgucuc cguccuuaca uccaaagucc ucgaccucaa gaacuacaua      720

gacaaacagc uacuacccau uguaaauaaa caaagcugcu caauuagcaa caucgaaacc      780

guaaucgagu uccagcagaa aaacaacaga cuucucgaaa ucacccgcga guucagcguc      840

aacgccggcg uaaccacccc ugucucaaca uacaugcuaa ccaacagcga acugcucucc      900

cucaucaacg acaugcccau caccaacgac caaaagaaac ucaugagcaa caacguacaa      960

aucgugcgcc aacaguccua cucaauaaug ucaaucauca aagaagaagu gcuagcauac     1020

gucguacaac uaccacucua cggcguaaua gauacccccu gcuggaagcu ccauaccucc     1080

ccacucugua ccaccaacac caaagaaggc ucaaacaucu gccuaacgcg cacagaccgu     1140

ggaugguacu gugacaacgc cggcuccguc uccuucuucc cucaagccga aacaugcaaa     1200

guccaaucca acagagucuu cugcgauacc augaacuccc ugacacuccc aagcgaaguc     1260

aaccuuugca acgucgauau cuuuaacccc aaauacgacu gcaagaucau gacaucaaaa     1320

accgacguau ccuccucugu aauaaccucc cuaggcgcaa ucguaucaug cuacggcaaa     1380

accaaaugua ccgccuccaa caaaaaucgc ggcaucauca aaaccuucuc gaacggcugc     1440

gacuacgucu ccaacaaagg cguagacaca guuuccguag gcaacacccu cuacuacguc     1500

aauaaacagg aaggcaaguc ccucuacguc aaaggcgaac ccaucaucaa uuucuacgac     1560

ccccucguuu uccccuccga ugaguucgac gcaagcauca gccaggucaa cgaaaagaua     1620

aaccaguccc ucgccuucau ccgcaaauca gaugaacucc uucacaacgu uaacgcaggc     1680

aagagcacca ccaacaucau gaucacaacu auaaucaucg ucauaaucgu cauccuacuc     1740

ucacuaaucg ccgucggucu ccuacuauau uguaaagccc gaucaacacc ggucacacuc     1800

uccaaagacc aacucuccgg aaucaacaau aucgcuuucu cgaacuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  294
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  294
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagaa gcacaccagu cacacuaagc aaagaucaac ugagugguau aaauaauauu     1800

gcauuuagua acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  295
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  295
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  296
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  296
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgca gcacgcccgu gacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gccuucucca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  297
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  297
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  298
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  298
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu caacacccgu uacguugagc aaggaccagc ucucugggau aaacaauauc     1800

gcuuucucca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  299
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  299
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  300
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  300
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu ccacccccgu uacgcugagc aaggaccagc uuucuggaau uaacaauauc     1800

gcuuucagca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  301
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  301
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauauuaaa agcuaacgca      120

aucacuacua ucuuaaccgc aguaacauuc uguuuugcau ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaacuug cucugcaguc ucaaaagguu aucuaucugc auuaagaaca      240

ggcugguaca ccucaguaau aacgaucgaa cuaucaaaca ucaaagaaaa caaauguaau      300

ggaacagacg caaaaguaaa acuaaucaaa caagaacuag acaaauacaa aaacgcagua      360

accgaacucc aacuccucau gcaaaguaca ccagcaacaa auaacagagc aagacgugaa      420

cuaccacguu uuaugaauua cacgcucaau aacgcaaaaa aaacaaaugu uacccuauca      480

aaaaaacgaa aaagaagauu ccucggauuc cuacuaggcg uaggcucagc aauagcuuca      540

ggaguagcag uaucaaaagu acuccaccuc gaaggagaag uaaacaaaau caaaagcgcu      600

cuccucucaa caaacaaagc aguuguuuca cucucaaacg gaguaucagu acuaaccuca      660

aaaguacuug accuaaaaaa uuauauagac aaacaacuau uaccaauagu aaacaaacaa      720

agcugcucca ucuccaacau cgagacaguc auagaauuuc aacaaaaaaa uaaccgccua      780

uuagaaauaa ccagagaauu uucaguaaac gcaggaguaa cuaccccagu aucaacauau      840

auguuaacaa acucagaacu ccuaagucua aucaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugagcaacaa uguacaaaua guucgucaac aaucuuacuc cauaaugucu      960

auaauaaaag aagaaguacu cgccuaugua guccaacuac cacuauacgg agucaucgau     1020

acaccaugcu ggaaacucca cacaucccca cucuguacua cuaacaccaa agaagguuca     1080

aauauaugcc uaaccagaac agauagaggu ugguacugcg auaaugcagg aucaguaucc     1140

uuuuuccccc aagccgaaac augcaaaguu caauccaaua gaguauuuug ugauacaaug     1200

aacucuuuaa cccucccauc cgaagucaau cuauguaacg ucgacauauu uaacccaaaa     1260

uacgauugca aaauaaugac aucaaaaaca gacgucucau ccucaguuau aacguccuua     1320

ggcgcuauag uaucaugcua cggcaaaaca aaauguacag caucaaacaa aaacagagga     1380

aucauaaaaa cuuucucuaa cgguugcgac uauguaucca acaaaggugu cgacacagua     1440

uccguaggca acacccuuua cuauguuaau aaacaagaag gaaaaucucu auauguaaaa     1500

ggcgaaccaa uuauaaauuu uuacgacccc cuugucuuuc ccucugacga auuugacgcu     1560

uccauaucac aagucaacga aaaaaucaac caaucccucg cauucauacg caaaucagac     1620

gaacuacuac auaacgucaa cgcaggcaaa uccacaacaa acauaaugau aaccacaauc     1680

auaauuguaa uaauaguaau acuacuuucu cuaauagcag ucggauuacu cuuauacugu     1740

aaagcucgau caacaccagu cacccucucu aaagaucaac uauccggaau caacaacaua     1800

gcuuucucaa acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  302
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  302
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauacucaa agccaacgca      120

aucacaacca uacucaccgc cgucaccuuc ugcuuugcau cuggccagaa caucacugaa      180

gaguucuacc aauccacaug cuccgccgua agcaaaggcu accuauccgc ccuacgcacc      240

ggcugguaca ccagcguaau caccauagaa cucuccaaua uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaagucaa gcuaauaaaa caagaacucg acaaauacaa aaacgccguu      360

accgaacucc agcuacucau gcaaucgacc ccagcaacca acaaccgugc gagacgcgaa      420

cucccccgcu ucaugaacua cacccuaaac aacgccaaaa agaccaacgu aacucuaucc      480

aagaaacgca aacgccgcuu ccucggauuc cuccucggcg ucggcuccgc aaucgccagc      540

ggcgucgccg uuagcaaagu ccuucaccuc gaaggagaag uaaacaaaau uaaaagcgcc      600

cucuuaucca caaacaaggc cguaguaucc cugucaaacg gcgucuccgu ccuuacaucc      660

aaaguccucg accucaagaa cuacauagac aaacagcuac uacccauugu aaauaaacaa      720

agcugcucaa uuagcaacau cgaaaccgua aucgaguucc agcagaaaaa caacagacuu      780

cucgaaauca cccgcgaguu cagcgucaac gccggcguaa ccaccccugu cucaacauac      840

augcuaacca acagcgaacu gcucucccuc aucaacgaca ugcccaucac caacgaccaa      900

aagaaacuca ugagcaacaa cguacaaauc gugcgccaac aguccuacuc aauaauguca      960

aucaucaaag aagaagugcu agcauacguc guacaacuac cacucuacgg cguaauagau     1020

acccccugcu ggaagcucca uaccucccca cucuguacca ccaacaccaa agaaggcuca     1080

aacaucugcc uaacgcgcac agaccgugga ugguacugug acaacgccgg cuccgucucc     1140

uucuucccuc aagccgaaac augcaaaguc caauccaaca gagucuucug cgauaccaug     1200

aacucccuga cacucccaag cgaagucaac cuuugcaacg ucgauaucuu uaaccccaaa     1260

uacgacugca agaucaugac aucaaaaacc gacguauccu ccucuguaau aaccucccua     1320

ggcgcaaucg uaucaugcua cggcaaaacc aaauguaccg ccuccaacaa aaaucgcggc     1380

aucaucaaaa ccuucucgaa cggcugcgac uacgucucca acaaaggcgu agacacaguu     1440

uccguaggca acacccucua cuacgucaau aaacaggaag gcaagucccu cuacgucaaa     1500

ggcgaaccca ucaucaauuu cuacgacccc cucguuuucc ccuccgauga guucgacgca     1560

agcaucagcc aggucaacga aaagauaaac cagucccucg ccuucauccg caaaucagau     1620

gaacuccuuc acaacguuaa cgcaggcaag agcaccacca acaucaugau cacaacuaua     1680

aucaucguca uaaucgucau ccuacucuca cuaaucgccg ucggucuccu acuauauugu     1740

aaagcccgau caacaccggu cacacucucc aaagaccaac ucuccggaau caacaauauc     1800

gcuuucucga acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  303
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  303
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagaa gcacaccagu cacacuaagc aaagaucaac ugagugguau aaauaauauu     1800

gcauuuagua acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  304
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  304
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  305
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  305
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgca gcacgcccgu gacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gccuucucca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  306
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  306
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  307
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  307
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu caacacccgu uacguugagc aaggaccagc ucucugggau aaacaauauc     1800

gcuuucucca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  308
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  308
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  309
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  309
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu ccacccccgu uacgcugagc aaggaccagc uuucuggaau uaacaauauc     1800

gcuuucagca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  310
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  310
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauauuaaa agcuaacgca      120

aucacuacua ucuuaaccgc aguaacauuc uguuuugcau ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaacuug cucugcaguc ucaaaagguu aucuaucugc auuaagaaca      240

ggcugguaca ccucaguaau aacgaucgaa cuaucaaaca ucaaagaaaa caaauguaau      300

ggaacagacg caaaaguaaa acuaaucaaa caagaacuag acaaauacaa aaacgcagua      360

accgaacucc aacuccucau gcaaaguaca ccagcaacaa auaacagagc aagacgugaa      420

cuaccacguu uuaugaauua cacgcucaau aacgcaaaaa aaacaaaugu uacccuauca      480

aaaaaacgaa aaagaagauu ccucggauuc cuacuaggcg uaggcucagc aauagcuuca      540

ggaguagcag uaucaaaagu acuccaccuc gaaggagaag uaaacaaaau caaaagcgcu      600

cuccucucaa caaacaaagc aguuguuuca cucucaaacg gaguaucagu acuaaccuca      660

aaaguacuug accuaaaaaa uuauauagac aaacaacuau uaccaauagu aaacaaacaa      720

agcugcucca ucuccaacau cgagacaguc auagaauuuc aacaaaaaaa uaaccgccua      780

uuagaaauaa ccagagaauu uucaguaaac gcaggaguaa cuaccccagu aucaacauau      840

auguuaacaa acucagaacu ccuaagucua aucaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugagcaacaa uguacaaaua guucgucaac aaucuuacuc cauaaugucu      960

auaauaaaag aagaaguacu cgccuaugua guccaacuac cacuauacgg agucaucgau     1020

acaccaugcu ggaaacucca cacaucccca cucuguacua cuaacaccaa agaagguuca     1080

aauauaugcc uaaccagaac agauagaggu ugguacugcg auaaugcagg aucaguaucc     1140

uuuuuccccc aagccgaaac augcaaaguu caauccaaua gaguauuuug ugauacaaug     1200

aacucuuuaa cccucccauc cgaagucaau cuauguaacg ucgacauauu uaacccaaaa     1260

uacgauugca aaauaaugac aucaaaaaca gacgucucau ccucaguuau aacguccuua     1320

ggcgcuauag uaucaugcua cggcaaaaca aaauguacag caucaaacaa aaacagagga     1380

aucauaaaaa cuuucucuaa cgguugcgac uauguaucca acaaaggugu cgacacagua     1440

uccguaggca acacccuuua cuauguuaau aaacaagaag gaaaaucucu auauguaaaa     1500

ggcgaaccaa uuauaaauuu uuacgacccc cuugucuuuc ccucugacga auuugacgcu     1560

uccauaucac aagucaacga aaaaaucaac caaucccucg cauucauacg caaaucagac     1620

gaacuacuac auaacgucaa cgcaggcaaa uccacaacaa acauaaugau aaccacaauc     1680

auaauuguaa uaauaguaau acuacuuucu cuaauagcag ucggauuacu cuuauacugu     1740

aaagcucgau caacaccagu cacccucucu aaagaucaac uauccggaau caacaacaua     1800

gcuuucucaa acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  311
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  311
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauacucaa agccaacgca      120

aucacaacca uacucaccgc cgucaccuuc ugcuuugcau cuggccagaa caucacugaa      180

gaguucuacc aauccacaug cuccgccgua agcaaaggcu accuauccgc ccuacgcacc      240

ggcugguaca ccagcguaau caccauagaa cucuccaaua uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaagucaa gcuaauaaaa caagaacucg acaaauacaa aaacgccguu      360

accgaacucc agcuacucau gcaaucgacc ccagcaacca acaaccgugc gagacgcgaa      420

cucccccgcu ucaugaacua cacccuaaac aacgccaaaa agaccaacgu aacucuaucc      480

aagaaacgca aacgccgcuu ccucggauuc cuccucggcg ucggcuccgc aaucgccagc      540

ggcgucgccg uuagcaaagu ccuucaccuc gaaggagaag uaaacaaaau uaaaagcgcc      600

cucuuaucca caaacaaggc cguaguaucc cugucaaacg gcgucuccgu ccuuacaucc      660

aaaguccucg accucaagaa cuacauagac aaacagcuac uacccauugu aaauaaacaa      720

agcugcucaa uuagcaacau cgaaaccgua aucgaguucc agcagaaaaa caacagacuu      780

cucgaaauca cccgcgaguu cagcgucaac gccggcguaa ccaccccugu cucaacauac      840

augcuaacca acagcgaacu gcucucccuc aucaacgaca ugcccaucac caacgaccaa      900

aagaaacuca ugagcaacaa cguacaaauc gugcgccaac aguccuacuc aauaauguca      960

aucaucaaag aagaagugcu agcauacguc guacaacuac cacucuacgg cguaauagau     1020

acccccugcu ggaagcucca uaccucccca cucuguacca ccaacaccaa agaaggcuca     1080

aacaucugcc uaacgcgcac agaccgugga ugguacugug acaacgccgg cuccgucucc     1140

uucuucccuc aagccgaaac augcaaaguc caauccaaca gagucuucug cgauaccaug     1200

aacucccuga cacucccaag cgaagucaac cuuugcaacg ucgauaucuu uaaccccaaa     1260

uacgacugca agaucaugac aucaaaaacc gacguauccu ccucuguaau aaccucccua     1320

ggcgcaaucg uaucaugcua cggcaaaacc aaauguaccg ccuccaacaa aaaucgcggc     1380

aucaucaaaa ccuucucgaa cggcugcgac uacgucucca acaaaggcgu agacacaguu     1440

uccguaggca acacccucua cuacgucaau aaacaggaag gcaagucccu cuacgucaaa     1500

ggcgaaccca ucaucaauuu cuacgacccc cucguuuucc ccuccgauga guucgacgca     1560

agcaucagcc aggucaacga aaagauaaac cagucccucg ccuucauccg caaaucagau     1620

gaacuccuuc acaacguuaa cgcaggcaag agcaccacca acaucaugau cacaacuaua     1680

aucaucguca uaaucgucau ccuacucuca cuaaucgccg ucggucuccu acuauauugu     1740

aaagcccgau caacaccggu cacacucucc aaagaccaac ucuccggaau caacaauauc     1800

gcuuucucga acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  312
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  312
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagaa gcacaccagu cacacuaagc aaagaucaac ugagugguau aaauaauauu     1800

gcauuuagua acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  313
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  313
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  314
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  314
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgca gcacgcccgu gacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gccuucucca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  315
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  315
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  316
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  316
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu caacacccgu uacguugagc aaggaccagc ucucugggau aaacaauauc     1800

gcuuucucca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  317
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  317
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  318
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  318
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu ccacccccgu uacgcugagc aaggaccagc uuucuggaau uaacaauauc     1800

gcuuucagca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  319
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  319
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauauuaaa agcuaacgca      120

aucacuacua ucuuaaccgc aguaacauuc uguuuugcau ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaacuug cucugcaguc ucaaaagguu aucuaucugc auuaagaaca      240

ggcugguaca ccucaguaau aacgaucgaa cuaucaaaca ucaaagaaaa caaauguaau      300

ggaacagacg caaaaguaaa acuaaucaaa caagaacuag acaaauacaa aaacgcagua      360

accgaacucc aacuccucau gcaaaguaca ccagcaacaa auaacagagc aagacgugaa      420

cuaccacguu uuaugaauua cacgcucaau aacgcaaaaa aaacaaaugu uacccuauca      480

aaaaaacgaa aaagaagauu ccucggauuc cuacuaggcg uaggcucagc aauagcuuca      540

ggaguagcag uaucaaaagu acuccaccuc gaaggagaag uaaacaaaau caaaagcgcu      600

cuccucucaa caaacaaagc aguuguuuca cucucaaacg gaguaucagu acuaaccuca      660

aaaguacuug accuaaaaaa uuauauagac aaacaacuau uaccaauagu aaacaaacaa      720

agcugcucca ucuccaacau cgagacaguc auagaauuuc aacaaaaaaa uaaccgccua      780

uuagaaauaa ccagagaauu uucaguaaac gcaggaguaa cuaccccagu aucaacauau      840

auguuaacaa acucagaacu ccuaagucua aucaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugagcaacaa uguacaaaua guucgucaac aaucuuacuc cauaaugucu      960

auaauaaaag aagaaguacu cgccuaugua guccaacuac cacuauacgg agucaucgau     1020

acaccaugcu ggaaacucca cacaucccca cucuguacua cuaacaccaa agaagguuca     1080

aauauaugcc uaaccagaac agauagaggu ugguacugcg auaaugcagg aucaguaucc     1140

uuuuuccccc aagccgaaac augcaaaguu caauccaaua gaguauuuug ugauacaaug     1200

aacucuuuaa cccucccauc cgaagucaau cuauguaacg ucgacauauu uaacccaaaa     1260

uacgauugca aaauaaugac aucaaaaaca gacgucucau ccucaguuau aacguccuua     1320

ggcgcuauag uaucaugcua cggcaaaaca aaauguacag caucaaacaa aaacagagga     1380

aucauaaaaa cuuucucuaa cgguugcgac uauguaucca acaaaggugu cgacacagua     1440

uccguaggca acacccuuua cuauguuaau aaacaagaag gaaaaucucu auauguaaaa     1500

ggcgaaccaa uuauaaauuu uuacgacccc cuugucuuuc ccucugacga auuugacgcu     1560

uccauaucac aagucaacga aaaaaucaac caaucccucg cauucauacg caaaucagac     1620

gaacuacuac auaacgucaa cgcaggcaaa uccacaacaa acauaaugau aaccacaauc     1680

auaauuguaa uaauaguaau acuacuuucu cuaauagcag ucggauuacu cuuauacugu     1740

aaagcucgau caacaccagu cacccucucu aaagaucaac uauccggaau caacaacaua     1800

gcuuucucaa acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  320
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  320
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauacucaa agccaacgca      120

aucacaacca uacucaccgc cgucaccuuc ugcuuugcau cuggccagaa caucacugaa      180

gaguucuacc aauccacaug cuccgccgua agcaaaggcu accuauccgc ccuacgcacc      240

ggcugguaca ccagcguaau caccauagaa cucuccaaua uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaagucaa gcuaauaaaa caagaacucg acaaauacaa aaacgccguu      360

accgaacucc agcuacucau gcaaucgacc ccagcaacca acaaccgugc gagacgcgaa      420

cucccccgcu ucaugaacua cacccuaaac aacgccaaaa agaccaacgu aacucuaucc      480

aagaaacgca aacgccgcuu ccucggauuc cuccucggcg ucggcuccgc aaucgccagc      540

ggcgucgccg uuagcaaagu ccuucaccuc gaaggagaag uaaacaaaau uaaaagcgcc      600

cucuuaucca caaacaaggc cguaguaucc cugucaaacg gcgucuccgu ccuuacaucc      660

aaaguccucg accucaagaa cuacauagac aaacagcuac uacccauugu aaauaaacaa      720

agcugcucaa uuagcaacau cgaaaccgua aucgaguucc agcagaaaaa caacagacuu      780

cucgaaauca cccgcgaguu cagcgucaac gccggcguaa ccaccccugu cucaacauac      840

augcuaacca acagcgaacu gcucucccuc aucaacgaca ugcccaucac caacgaccaa      900

aagaaacuca ugagcaacaa cguacaaauc gugcgccaac aguccuacuc aauaauguca      960

aucaucaaag aagaagugcu agcauacguc guacaacuac cacucuacgg cguaauagau     1020

acccccugcu ggaagcucca uaccucccca cucuguacca ccaacaccaa agaaggcuca     1080

aacaucugcc uaacgcgcac agaccgugga ugguacugug acaacgccgg cuccgucucc     1140

uucuucccuc aagccgaaac augcaaaguc caauccaaca gagucuucug cgauaccaug     1200

aacucccuga cacucccaag cgaagucaac cuuugcaacg ucgauaucuu uaaccccaaa     1260

uacgacugca agaucaugac aucaaaaacc gacguauccu ccucuguaau aaccucccua     1320

ggcgcaaucg uaucaugcua cggcaaaacc aaauguaccg ccuccaacaa aaaucgcggc     1380

aucaucaaaa ccuucucgaa cggcugcgac uacgucucca acaaaggcgu agacacaguu     1440

uccguaggca acacccucua cuacgucaau aaacaggaag gcaagucccu cuacgucaaa     1500

ggcgaaccca ucaucaauuu cuacgacccc cucguuuucc ccuccgauga guucgacgca     1560

agcaucagcc aggucaacga aaagauaaac cagucccucg ccuucauccg caaaucagau     1620

gaacuccuuc acaacguuaa cgcaggcaag agcaccacca acaucaugau cacaacuaua     1680

aucaucguca uaaucgucau ccuacucuca cuaaucgccg ucggucuccu acuauauugu     1740

aaagcccgau caacaccggu cacacucucc aaagaccaac ucuccggaau caacaauauc     1800

gcuuucucga acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  321
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  321
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagaa gcacaccagu cacacuaagc aaagaucaac ugagugguau aaauaauauu     1800

gcauuuagua acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  322
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  322
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  323
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  323
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgca gcacgcccgu gacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gccuucucca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  324
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  324
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  325
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  325
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu caacacccgu uacguugagc aaggaccagc ucucugggau aaacaauauc     1800

gcuuucucca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  326
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  326
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  327
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  327
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu ccacccccgu uacgcugagc aaggaccagc uuucuggaau uaacaauauc     1800

gcuuucagca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  328
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  328
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauauuaaa agcuaacgca      120

aucacuacua ucuuaaccgc aguaacauuc uguuuugcau ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaacuug cucugcaguc ucaaaagguu aucuaucugc auuaagaaca      240

ggcugguaca ccucaguaau aacgaucgaa cuaucaaaca ucaaagaaaa caaauguaau      300

ggaacagacg caaaaguaaa acuaaucaaa caagaacuag acaaauacaa aaacgcagua      360

accgaacucc aacuccucau gcaaaguaca ccagcaacaa auaacagagc aagacgugaa      420

cuaccacguu uuaugaauua cacgcucaau aacgcaaaaa aaacaaaugu uacccuauca      480

aaaaaacgaa aaagaagauu ccucggauuc cuacuaggcg uaggcucagc aauagcuuca      540

ggaguagcag uaucaaaagu acuccaccuc gaaggagaag uaaacaaaau caaaagcgcu      600

cuccucucaa caaacaaagc aguuguuuca cucucaaacg gaguaucagu acuaaccuca      660

aaaguacuug accuaaaaaa uuauauagac aaacaacuau uaccaauagu aaacaaacaa      720

agcugcucca ucuccaacau cgagacaguc auagaauuuc aacaaaaaaa uaaccgccua      780

uuagaaauaa ccagagaauu uucaguaaac gcaggaguaa cuaccccagu aucaacauau      840

auguuaacaa acucagaacu ccuaagucua aucaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugagcaacaa uguacaaaua guucgucaac aaucuuacuc cauaaugucu      960

auaauaaaag aagaaguacu cgccuaugua guccaacuac cacuauacgg agucaucgau     1020

acaccaugcu ggaaacucca cacaucccca cucuguacua cuaacaccaa agaagguuca     1080

aauauaugcc uaaccagaac agauagaggu ugguacugcg auaaugcagg aucaguaucc     1140

uuuuuccccc aagccgaaac augcaaaguu caauccaaua gaguauuuug ugauacaaug     1200

aacucuuuaa cccucccauc cgaagucaau cuauguaacg ucgacauauu uaacccaaaa     1260

uacgauugca aaauaaugac aucaaaaaca gacgucucau ccucaguuau aacguccuua     1320

ggcgcuauag uaucaugcua cggcaaaaca aaauguacag caucaaacaa aaacagagga     1380

aucauaaaaa cuuucucuaa cgguugcgac uauguaucca acaaaggugu cgacacagua     1440

uccguaggca acacccuuua cuauguuaau aaacaagaag gaaaaucucu auauguaaaa     1500

ggcgaaccaa uuauaaauuu uuacgacccc cuugucuuuc ccucugacga auuugacgcu     1560

uccauaucac aagucaacga aaaaaucaac caaucccucg cauucauacg caaaucagac     1620

gaacuacuac auaacgucaa cgcaggcaaa uccacaacaa acauaaugau aaccacaauc     1680

auaauuguaa uaauaguaau acuacuuucu cuaauagcag ucggauuacu cuuauacugu     1740

aaagcucgau caacaccagu cacccucucu aaagaucaac uauccggaau caacaacaua     1800

gcuuucucaa acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  329
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  329
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauacucaa agccaacgca      120

aucacaacca uacucaccgc cgucaccuuc ugcuuugcau cuggccagaa caucacugaa      180

gaguucuacc aauccacaug cuccgccgua agcaaaggcu accuauccgc ccuacgcacc      240

ggcugguaca ccagcguaau caccauagaa cucuccaaua uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaagucaa gcuaauaaaa caagaacucg acaaauacaa aaacgccguu      360

accgaacucc agcuacucau gcaaucgacc ccagcaacca acaaccgugc gagacgcgaa      420

cucccccgcu ucaugaacua cacccuaaac aacgccaaaa agaccaacgu aacucuaucc      480

aagaaacgca aacgccgcuu ccucggauuc cuccucggcg ucggcuccgc aaucgccagc      540

ggcgucgccg uuagcaaagu ccuucaccuc gaaggagaag uaaacaaaau uaaaagcgcc      600

cucuuaucca caaacaaggc cguaguaucc cugucaaacg gcgucuccgu ccuuacaucc      660

aaaguccucg accucaagaa cuacauagac aaacagcuac uacccauugu aaauaaacaa      720

agcugcucaa uuagcaacau cgaaaccgua aucgaguucc agcagaaaaa caacagacuu      780

cucgaaauca cccgcgaguu cagcgucaac gccggcguaa ccaccccugu cucaacauac      840

augcuaacca acagcgaacu gcucucccuc aucaacgaca ugcccaucac caacgaccaa      900

aagaaacuca ugagcaacaa cguacaaauc gugcgccaac aguccuacuc aauaauguca      960

aucaucaaag aagaagugcu agcauacguc guacaacuac cacucuacgg cguaauagau     1020

acccccugcu ggaagcucca uaccucccca cucuguacca ccaacaccaa agaaggcuca     1080

aacaucugcc uaacgcgcac agaccgugga ugguacugug acaacgccgg cuccgucucc     1140

uucuucccuc aagccgaaac augcaaaguc caauccaaca gagucuucug cgauaccaug     1200

aacucccuga cacucccaag cgaagucaac cuuugcaacg ucgauaucuu uaaccccaaa     1260

uacgacugca agaucaugac aucaaaaacc gacguauccu ccucuguaau aaccucccua     1320

ggcgcaaucg uaucaugcua cggcaaaacc aaauguaccg ccuccaacaa aaaucgcggc     1380

aucaucaaaa ccuucucgaa cggcugcgac uacgucucca acaaaggcgu agacacaguu     1440

uccguaggca acacccucua cuacgucaau aaacaggaag gcaagucccu cuacgucaaa     1500

ggcgaaccca ucaucaauuu cuacgacccc cucguuuucc ccuccgauga guucgacgca     1560

agcaucagcc aggucaacga aaagauaaac cagucccucg ccuucauccg caaaucagau     1620

gaacuccuuc acaacguuaa cgcaggcaag agcaccacca acaucaugau cacaacuaua     1680

aucaucguca uaaucgucau ccuacucuca cuaaucgccg ucggucuccu acuauauugu     1740

aaagcccgau caacaccggu cacacucucc aaagaccaac ucuccggaau caacaauauc     1800

gcuuucucga acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  330
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  330
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagaagca     1740

caccagucac acuaagcaaa gaucaacuga gugguauaaa uaauauugca uuuaguaacu     1800

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  331
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  331
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  332
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  332
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca     1740

cgcccgugac ccuguccaag gaccagcuga gcggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  333
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  333
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  334
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  334
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggucaa     1740

cacccguuac guugagcaag gaccagcucu cugggauaaa caauaucgcu uucuccaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  335
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  335
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  336
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  336
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggucca     1740

cccccguuac gcugagcaag gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  337
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  337
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu      120

uaaccgcagu aacauucugu uuugcauccg gccaaaacau aacagaagaa uuuuaccaau      180

caacuugcuc ugcagucuca aaagguuauc uaucugcauu aagaacaggc ugguacaccu      240

caguaauaac gaucgaacua ucaaacauca aagaaaacaa auguaaugga acagacgcaa      300

aaguaaaacu aaucaaacaa gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac      360

uccucaugca aaguacacca gcaacaaaua acagagcaag acgugaacua ccacguuuua      420

ugaauuacac gcucaauaac gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa      480

gaagauuccu cggauuccua cuaggcguag gcucagcaau agcuucagga guagcaguau      540

caaaaguacu ccaccucgaa ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa      600

acaaagcagu uguuucacuc ucaaacggag uaucaguacu aaccucaaaa guacuugacc      660

uaaaaaauua uauagacaaa caacuauuac caauaguaaa caaacaaagc ugcuccaucu      720

ccaacaucga gacagucaua gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca      780

gagaauuuuc aguaaacgca ggaguaacua ccccaguauc aacauauaug uuaacaaacu      840

cagaacuccu aagucuaauc aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga      900

gcaacaaugu acaaauaguu cgucaacaau cuuacuccau aaugucuaua auaaaagaag      960

aaguacucgc cuauguaguc caacuaccac uauacggagu caucgauaca ccaugcugga     1020

aacuccacac auccccacuc uguacuacua acaccaaaga agguucaaau auaugccuaa     1080

ccagaacaga uagagguugg uacugcgaua augcaggauc aguauccuuu uucccccaag     1140

ccgaaacaug caaaguucaa uccaauagag uauuuuguga uacaaugaac ucuuuaaccc     1200

ucccauccga agucaaucua uguaacgucg acauauuuaa cccaaaauac gauugcaaaa     1260

uaaugacauc aaaaacagac gucucauccu caguuauaac guccuuaggc gcuauaguau     1320

caugcuacgg caaaacaaaa uguacagcau caaacaaaaa cagaggaauc auaaaaacuu     1380

ucucuaacgg uugcgacuau guauccaaca aaggugucga cacaguaucc guaggcaaca     1440

cccuuuacua uguuaauaaa caagaaggaa aaucucuaua uguaaaaggc gaaccaauua     1500

uaaauuuuua cgacccccuu gucuuucccu cugacgaauu ugacgcuucc auaucacaag     1560

ucaacgaaaa aaucaaccaa ucccucgcau ucauacgcaa aucagacgaa cuacuacaua     1620

acgucaacgc aggcaaaucc acaacaaaca uaaugauaac cacaaucaua auuguaauaa     1680

uaguaauacu acuuucucua auagcagucg gauuacucuu auacuguaaa gcucgaucaa     1740

caccagucac ccucucuaaa gaucaacuau ccggaaucaa caacauagcu uucucaaacu     1800

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  338
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  338
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uacucaaagc caacgcaauc acaaccauac      120

ucaccgccgu caccuucugc uuugcaucug gccagaacau cacugaagag uucuaccaau      180

ccacaugcuc cgccguaagc aaaggcuacc uauccgcccu acgcaccggc ugguacacca      240

gcguaaucac cauagaacuc uccaauauaa aagaaaacaa augcaacggc accgacgcaa      300

aagucaagcu aauaaaacaa gaacucgaca aauacaaaaa cgccguuacc gaacuccagc      360

uacucaugca aucgacccca gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca      420

ugaacuacac ccuaaacaac gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac      480

gccgcuuccu cggauuccuc cucggcgucg gcuccgcaau cgccagcggc gucgccguua      540

gcaaaguccu ucaccucgaa ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa      600

acaaggccgu aguaucccug ucaaacggcg ucuccguccu uacauccaaa guccucgacc      660

ucaagaacua cauagacaaa cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua      720

gcaacaucga aaccguaauc gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc      780

gcgaguucag cgucaacgcc ggcguaacca ccccugucuc aacauacaug cuaaccaaca      840

gcgaacugcu cucccucauc aacgacaugc ccaucaccaa cgaccaaaag aaacucauga      900

gcaacaacgu acaaaucgug cgccaacagu ccuacucaau aaugucaauc aucaaagaag      960

aagugcuagc auacgucgua caacuaccac ucuacggcgu aauagauacc cccugcugga     1020

agcuccauac cuccccacuc uguaccacca acaccaaaga aggcucaaac aucugccuaa     1080

cgcgcacaga ccguggaugg uacugugaca acgccggcuc cgucuccuuc uucccucaag     1140

ccgaaacaug caaaguccaa uccaacagag ucuucugcga uaccaugaac ucccugacac     1200

ucccaagcga agucaaccuu ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga     1260

ucaugacauc aaaaaccgac guauccuccu cuguaauaac cucccuaggc gcaaucguau     1320

caugcuacgg caaaaccaaa uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu     1380

ucucgaacgg cugcgacuac gucuccaaca aaggcguaga cacaguuucc guaggcaaca     1440

cccucuacua cgucaauaaa caggaaggca agucccucua cgucaaaggc gaacccauca     1500

ucaauuucua cgacccccuc guuuuccccu ccgaugaguu cgacgcaagc aucagccagg     1560

ucaacgaaaa gauaaaccag ucccucgccu ucauccgcaa aucagaugaa cuccuucaca     1620

acguuaacgc aggcaagagc accaccaaca ucaugaucac aacuauaauc aucgucauaa     1680

ucgucauccu acucucacua aucgccgucg gucuccuacu auauuguaaa gcccgaucaa     1740

caccggucac acucuccaaa gaccaacucu ccggaaucaa caauaucgcu uucucgaacu     1800

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  339
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  339
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagaagca     1740

caccagucac acuaagcaaa gaucaacuga gugguauaaa uaauauugca uuuaguaacu     1800

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  340
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  340
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  341
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  341
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca     1740

cgcccgugac ccuguccaag gaccagcuga gcggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  342
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  342
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  343
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  343
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggucaa     1740

cacccguuac guugagcaag gaccagcucu cugggauaaa caauaucgcu uucuccaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  344
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  344
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  345
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  345
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggucca     1740

cccccguuac gcugagcaag gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  346
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  346
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu      120

uaaccgcagu aacauucugu uuugcauccg gccaaaacau aacagaagaa uuuuaccaau      180

caacuugcuc ugcagucuca aaagguuauc uaucugcauu aagaacaggc ugguacaccu      240

caguaauaac gaucgaacua ucaaacauca aagaaaacaa auguaaugga acagacgcaa      300

aaguaaaacu aaucaaacaa gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac      360

uccucaugca aaguacacca gcaacaaaua acagagcaag acgugaacua ccacguuuua      420

ugaauuacac gcucaauaac gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa      480

gaagauuccu cggauuccua cuaggcguag gcucagcaau agcuucagga guagcaguau      540

caaaaguacu ccaccucgaa ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa      600

acaaagcagu uguuucacuc ucaaacggag uaucaguacu aaccucaaaa guacuugacc      660

uaaaaaauua uauagacaaa caacuauuac caauaguaaa caaacaaagc ugcuccaucu      720

ccaacaucga gacagucaua gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca      780

gagaauuuuc aguaaacgca ggaguaacua ccccaguauc aacauauaug uuaacaaacu      840

cagaacuccu aagucuaauc aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga      900

gcaacaaugu acaaauaguu cgucaacaau cuuacuccau aaugucuaua auaaaagaag      960

aaguacucgc cuauguaguc caacuaccac uauacggagu caucgauaca ccaugcugga     1020

aacuccacac auccccacuc uguacuacua acaccaaaga agguucaaau auaugccuaa     1080

ccagaacaga uagagguugg uacugcgaua augcaggauc aguauccuuu uucccccaag     1140

ccgaaacaug caaaguucaa uccaauagag uauuuuguga uacaaugaac ucuuuaaccc     1200

ucccauccga agucaaucua uguaacgucg acauauuuaa cccaaaauac gauugcaaaa     1260

uaaugacauc aaaaacagac gucucauccu caguuauaac guccuuaggc gcuauaguau     1320

caugcuacgg caaaacaaaa uguacagcau caaacaaaaa cagaggaauc auaaaaacuu     1380

ucucuaacgg uugcgacuau guauccaaca aaggugucga cacaguaucc guaggcaaca     1440

cccuuuacua uguuaauaaa caagaaggaa aaucucuaua uguaaaaggc gaaccaauua     1500

uaaauuuuua cgacccccuu gucuuucccu cugacgaauu ugacgcuucc auaucacaag     1560

ucaacgaaaa aaucaaccaa ucccucgcau ucauacgcaa aucagacgaa cuacuacaua     1620

acgucaacgc aggcaaaucc acaacaaaca uaaugauaac cacaaucaua auuguaauaa     1680

uaguaauacu acuuucucua auagcagucg gauuacucuu auacuguaaa gcucgaucaa     1740

caccagucac ccucucuaaa gaucaacuau ccggaaucaa caacauagcu uucucaaacu     1800

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  347
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  347
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uacucaaagc caacgcaauc acaaccauac      120

ucaccgccgu caccuucugc uuugcaucug gccagaacau cacugaagag uucuaccaau      180

ccacaugcuc cgccguaagc aaaggcuacc uauccgcccu acgcaccggc ugguacacca      240

gcguaaucac cauagaacuc uccaauauaa aagaaaacaa augcaacggc accgacgcaa      300

aagucaagcu aauaaaacaa gaacucgaca aauacaaaaa cgccguuacc gaacuccagc      360

uacucaugca aucgacccca gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca      420

ugaacuacac ccuaaacaac gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac      480

gccgcuuccu cggauuccuc cucggcgucg gcuccgcaau cgccagcggc gucgccguua      540

gcaaaguccu ucaccucgaa ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa      600

acaaggccgu aguaucccug ucaaacggcg ucuccguccu uacauccaaa guccucgacc      660

ucaagaacua cauagacaaa cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua      720

gcaacaucga aaccguaauc gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc      780

gcgaguucag cgucaacgcc ggcguaacca ccccugucuc aacauacaug cuaaccaaca      840

gcgaacugcu cucccucauc aacgacaugc ccaucaccaa cgaccaaaag aaacucauga      900

gcaacaacgu acaaaucgug cgccaacagu ccuacucaau aaugucaauc aucaaagaag      960

aagugcuagc auacgucgua caacuaccac ucuacggcgu aauagauacc cccugcugga     1020

agcuccauac cuccccacuc uguaccacca acaccaaaga aggcucaaac aucugccuaa     1080

cgcgcacaga ccguggaugg uacugugaca acgccggcuc cgucuccuuc uucccucaag     1140

ccgaaacaug caaaguccaa uccaacagag ucuucugcga uaccaugaac ucccugacac     1200

ucccaagcga agucaaccuu ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga     1260

ucaugacauc aaaaaccgac guauccuccu cuguaauaac cucccuaggc gcaaucguau     1320

caugcuacgg caaaaccaaa uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu     1380

ucucgaacgg cugcgacuac gucuccaaca aaggcguaga cacaguuucc guaggcaaca     1440

cccucuacua cgucaauaaa caggaaggca agucccucua cgucaaaggc gaacccauca     1500

ucaauuucua cgacccccuc guuuuccccu ccgaugaguu cgacgcaagc aucagccagg     1560

ucaacgaaaa gauaaaccag ucccucgccu ucauccgcaa aucagaugaa cuccuucaca     1620

acguuaacgc aggcaagagc accaccaaca ucaugaucac aacuauaauc aucgucauaa     1680

ucgucauccu acucucacua aucgccgucg gucuccuacu auauuguaaa gcccgaucaa     1740

caccggucac acucuccaaa gaccaacucu ccggaaucaa caauaucgcu uucucgaacu     1800

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  348
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  348
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaag cacaccaguc     1740

acacuaagca aagaucaacu gagugguaua aauaauauug cauuuaguaa cuaaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  349
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  349
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  350
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  350
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcag cacgcccgug     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  351
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  351
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  352
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  352
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccagguc aacacccguu     1740

acguugagca aggaccagcu cucugggaua aacaauaucg cuuucuccaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  353
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  353
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  354
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  354
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccgguc cacccccguu     1740

acgcugagca aggaccagcu uucuggaauu aacaauaucg cuuucagcaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  355
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  355
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauauuaaaa gcuaacgcaa ucacuacuau cuuaaccgca      120

guaacauucu guuuugcauc cggccaaaac auaacagaag aauuuuacca aucaacuugc      180

ucugcagucu caaaagguua ucuaucugca uuaagaacag gcugguacac cucaguaaua      240

acgaucgaac uaucaaacau caaagaaaac aaauguaaug gaacagacgc aaaaguaaaa      300

cuaaucaaac aagaacuaga caaauacaaa aacgcaguaa ccgaacucca acuccucaug      360

caaaguacac cagcaacaaa uaacagagca agacgugaac uaccacguuu uaugaauuac      420

acgcucaaua acgcaaaaaa aacaaauguu acccuaucaa aaaaacgaaa aagaagauuc      480

cucggauucc uacuaggcgu aggcucagca auagcuucag gaguagcagu aucaaaagua      540

cuccaccucg aaggagaagu aaacaaaauc aaaagcgcuc uccucucaac aaacaaagca      600

guuguuucac ucucaaacgg aguaucagua cuaaccucaa aaguacuuga ccuaaaaaau      660

uauauagaca aacaacuauu accaauagua aacaaacaaa gcugcuccau cuccaacauc      720

gagacaguca uagaauuuca acaaaaaaau aaccgccuau uagaaauaac cagagaauuu      780

ucaguaaacg caggaguaac uaccccagua ucaacauaua uguuaacaaa cucagaacuc      840

cuaagucuaa ucaacgacau gccaauaacc aacgaccaaa aaaaacuaau gagcaacaau      900

guacaaauag uucgucaaca aucuuacucc auaaugucua uaauaaaaga agaaguacuc      960

gccuauguag uccaacuacc acuauacgga gucaucgaua caccaugcug gaaacuccac     1020

acauccccac ucuguacuac uaacaccaaa gaagguucaa auauaugccu aaccagaaca     1080

gauagagguu gguacugcga uaaugcagga ucaguauccu uuuuccccca agccgaaaca     1140

ugcaaaguuc aauccaauag aguauuuugu gauacaauga acucuuuaac ccucccaucc     1200

gaagucaauc uauguaacgu cgacauauuu aacccaaaau acgauugcaa aauaaugaca     1260

ucaaaaacag acgucucauc cucaguuaua acguccuuag gcgcuauagu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaacaaa aacagaggaa ucauaaaaac uuucucuaac     1380

gguugcgacu auguauccaa caaagguguc gacacaguau ccguaggcaa cacccuuuac     1440

uauguuaaua aacaagaagg aaaaucucua uauguaaaag gcgaaccaau uauaaauuuu     1500

uacgaccccc uugucuuucc cucugacgaa uuugacgcuu ccauaucaca agucaacgaa     1560

aaaaucaacc aaucccucgc auucauacgc aaaucagacg aacuacuaca uaacgucaac     1620

gcaggcaaau ccacaacaaa cauaaugaua accacaauca uaauuguaau aauaguaaua     1680

cuacuuucuc uaauagcagu cggauuacuc uuauacugua aagcucgauc aacaccaguc     1740

acccucucua aagaucaacu auccggaauc aacaacauag cuuucucaaa cuaaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  356
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  356
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauacucaaa gccaacgcaa ucacaaccau acucaccgcc      120

gucaccuucu gcuuugcauc uggccagaac aucacugaag aguucuacca auccacaugc      180

uccgccguaa gcaaaggcua ccuauccgcc cuacgcaccg gcugguacac cagcguaauc      240

accauagaac ucuccaauau aaaagaaaac aaaugcaacg gcaccgacgc aaaagucaag      300

cuaauaaaac aagaacucga caaauacaaa aacgccguua ccgaacucca gcuacucaug      360

caaucgaccc cagcaaccaa caaccgugcg agacgcgaac ucccccgcuu caugaacuac      420

acccuaaaca acgccaaaaa gaccaacgua acucuaucca agaaacgcaa acgccgcuuc      480

cucggauucc uccucggcgu cggcuccgca aucgccagcg gcgucgccgu uagcaaaguc      540

cuucaccucg aaggagaagu aaacaaaauu aaaagcgccc ucuuauccac aaacaaggcc      600

guaguauccc ugucaaacgg cgucuccguc cuuacaucca aaguccucga ccucaagaac      660

uacauagaca aacagcuacu acccauugua aauaaacaaa gcugcucaau uagcaacauc      720

gaaaccguaa ucgaguucca gcagaaaaac aacagacuuc ucgaaaucac ccgcgaguuc      780

agcgucaacg ccggcguaac caccccuguc ucaacauaca ugcuaaccaa cagcgaacug      840

cucucccuca ucaacgacau gcccaucacc aacgaccaaa agaaacucau gagcaacaac      900

guacaaaucg ugcgccaaca guccuacuca auaaugucaa ucaucaaaga agaagugcua      960

gcauacgucg uacaacuacc acucuacggc guaauagaua cccccugcug gaagcuccau     1020

accuccccac ucuguaccac caacaccaaa gaaggcucaa acaucugccu aacgcgcaca     1080

gaccguggau gguacuguga caacgccggc uccgucuccu ucuucccuca agccgaaaca     1140

ugcaaagucc aauccaacag agucuucugc gauaccauga acucccugac acucccaagc     1200

gaagucaacc uuugcaacgu cgauaucuuu aaccccaaau acgacugcaa gaucaugaca     1260

ucaaaaaccg acguauccuc cucuguaaua accucccuag gcgcaaucgu aucaugcuac     1320

ggcaaaacca aauguaccgc cuccaacaaa aaucgcggca ucaucaaaac cuucucgaac     1380

ggcugcgacu acgucuccaa caaaggcgua gacacaguuu ccguaggcaa cacccucuac     1440

uacgucaaua aacaggaagg caagucccuc uacgucaaag gcgaacccau caucaauuuc     1500

uacgaccccc ucguuuuccc cuccgaugag uucgacgcaa gcaucagcca ggucaacgaa     1560

aagauaaacc agucccucgc cuucauccgc aaaucagaug aacuccuuca caacguuaac     1620

gcaggcaaga gcaccaccaa caucaugauc acaacuauaa ucaucgucau aaucgucauc     1680

cuacucucac uaaucgccgu cggucuccua cuauauugua aagcccgauc aacaccgguc     1740

acacucucca aagaccaacu cuccggaauc aacaauaucg cuuucucgaa cuaaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  357
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  357
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaag cacaccaguc     1740

acacuaagca aagaucaacu gagugguaua aauaauauug cauuuaguaa cuaaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  358
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  358
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  359
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  359
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcag cacgcccgug     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  360
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  360
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  361
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  361
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccagguc aacacccguu     1740

acguugagca aggaccagcu cucugggaua aacaauaucg cuuucuccaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  362
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  362
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  363
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  363
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccgguc cacccccguu     1740

acgcugagca aggaccagcu uucuggaauu aacaauaucg cuuucagcaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  364
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  364
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauauuaaaa gcuaacgcaa ucacuacuau cuuaaccgca      120

guaacauucu guuuugcauc cggccaaaac auaacagaag aauuuuacca aucaacuugc      180

ucugcagucu caaaagguua ucuaucugca uuaagaacag gcugguacac cucaguaaua      240

acgaucgaac uaucaaacau caaagaaaac aaauguaaug gaacagacgc aaaaguaaaa      300

cuaaucaaac aagaacuaga caaauacaaa aacgcaguaa ccgaacucca acuccucaug      360

caaaguacac cagcaacaaa uaacagagca agacgugaac uaccacguuu uaugaauuac      420

acgcucaaua acgcaaaaaa aacaaauguu acccuaucaa aaaaacgaaa aagaagauuc      480

cucggauucc uacuaggcgu aggcucagca auagcuucag gaguagcagu aucaaaagua      540

cuccaccucg aaggagaagu aaacaaaauc aaaagcgcuc uccucucaac aaacaaagca      600

guuguuucac ucucaaacgg aguaucagua cuaaccucaa aaguacuuga ccuaaaaaau      660

uauauagaca aacaacuauu accaauagua aacaaacaaa gcugcuccau cuccaacauc      720

gagacaguca uagaauuuca acaaaaaaau aaccgccuau uagaaauaac cagagaauuu      780

ucaguaaacg caggaguaac uaccccagua ucaacauaua uguuaacaaa cucagaacuc      840

cuaagucuaa ucaacgacau gccaauaacc aacgaccaaa aaaaacuaau gagcaacaau      900

guacaaauag uucgucaaca aucuuacucc auaaugucua uaauaaaaga agaaguacuc      960

gccuauguag uccaacuacc acuauacgga gucaucgaua caccaugcug gaaacuccac     1020

acauccccac ucuguacuac uaacaccaaa gaagguucaa auauaugccu aaccagaaca     1080

gauagagguu gguacugcga uaaugcagga ucaguauccu uuuuccccca agccgaaaca     1140

ugcaaaguuc aauccaauag aguauuuugu gauacaauga acucuuuaac ccucccaucc     1200

gaagucaauc uauguaacgu cgacauauuu aacccaaaau acgauugcaa aauaaugaca     1260

ucaaaaacag acgucucauc cucaguuaua acguccuuag gcgcuauagu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaacaaa aacagaggaa ucauaaaaac uuucucuaac     1380

gguugcgacu auguauccaa caaagguguc gacacaguau ccguaggcaa cacccuuuac     1440

uauguuaaua aacaagaagg aaaaucucua uauguaaaag gcgaaccaau uauaaauuuu     1500

uacgaccccc uugucuuucc cucugacgaa uuugacgcuu ccauaucaca agucaacgaa     1560

aaaaucaacc aaucccucgc auucauacgc aaaucagacg aacuacuaca uaacgucaac     1620

gcaggcaaau ccacaacaaa cauaaugaua accacaauca uaauuguaau aauaguaaua     1680

cuacuuucuc uaauagcagu cggauuacuc uuauacugua aagcucgauc aacaccaguc     1740

acccucucua aagaucaacu auccggaauc aacaacauag cuuucucaaa cuaaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  365
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  365
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauacucaaa gccaacgcaa ucacaaccau acucaccgcc      120

gucaccuucu gcuuugcauc uggccagaac aucacugaag aguucuacca auccacaugc      180

uccgccguaa gcaaaggcua ccuauccgcc cuacgcaccg gcugguacac cagcguaauc      240

accauagaac ucuccaauau aaaagaaaac aaaugcaacg gcaccgacgc aaaagucaag      300

cuaauaaaac aagaacucga caaauacaaa aacgccguua ccgaacucca gcuacucaug      360

caaucgaccc cagcaaccaa caaccgugcg agacgcgaac ucccccgcuu caugaacuac      420

acccuaaaca acgccaaaaa gaccaacgua acucuaucca agaaacgcaa acgccgcuuc      480

cucggauucc uccucggcgu cggcuccgca aucgccagcg gcgucgccgu uagcaaaguc      540

cuucaccucg aaggagaagu aaacaaaauu aaaagcgccc ucuuauccac aaacaaggcc      600

guaguauccc ugucaaacgg cgucuccguc cuuacaucca aaguccucga ccucaagaac      660

uacauagaca aacagcuacu acccauugua aauaaacaaa gcugcucaau uagcaacauc      720

gaaaccguaa ucgaguucca gcagaaaaac aacagacuuc ucgaaaucac ccgcgaguuc      780

agcgucaacg ccggcguaac caccccuguc ucaacauaca ugcuaaccaa cagcgaacug      840

cucucccuca ucaacgacau gcccaucacc aacgaccaaa agaaacucau gagcaacaac      900

guacaaaucg ugcgccaaca guccuacuca auaaugucaa ucaucaaaga agaagugcua      960

gcauacgucg uacaacuacc acucuacggc guaauagaua cccccugcug gaagcuccau     1020

accuccccac ucuguaccac caacaccaaa gaaggcucaa acaucugccu aacgcgcaca     1080

gaccguggau gguacuguga caacgccggc uccgucuccu ucuucccuca agccgaaaca     1140

ugcaaagucc aauccaacag agucuucugc gauaccauga acucccugac acucccaagc     1200

gaagucaacc uuugcaacgu cgauaucuuu aaccccaaau acgacugcaa gaucaugaca     1260

ucaaaaaccg acguauccuc cucuguaaua accucccuag gcgcaaucgu aucaugcuac     1320

ggcaaaacca aauguaccgc cuccaacaaa aaucgcggca ucaucaaaac cuucucgaac     1380

ggcugcgacu acgucuccaa caaaggcgua gacacaguuu ccguaggcaa cacccucuac     1440

uacgucaaua aacaggaagg caagucccuc uacgucaaag gcgaacccau caucaauuuc     1500

uacgaccccc ucguuuuccc cuccgaugag uucgacgcaa gcaucagcca ggucaacgaa     1560

aagauaaacc agucccucgc cuucauccgc aaaucagaug aacuccuuca caacguuaac     1620

gcaggcaaga gcaccaccaa caucaugauc acaacuauaa ucaucgucau aaucgucauc     1680

cuacucucac uaaucgccgu cggucuccua cuauauugua aagcccgauc aacaccgguc     1740

acacucucca aagaccaacu cuccggaauc aacaauaucg cuuucucgaa cuaaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  366
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  366
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagaagcac accagucaca cuaagcaaag aucaacugag ugguauaaau     1800

aauauugcau uuaguaacua aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  367
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  367
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  368
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  368
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcagcac gcccgugacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  369
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  369
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  370
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  370
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggucaac acccguuacg uugagcaagg accagcucuc ugggauaaac     1800

aauaucgcuu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  371
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  371
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  372
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  372
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccgguccac ccccguuacg cugagcaagg accagcuuuc uggaauuaac     1800

aauaucgcuu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  373
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  373
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau auuaaaagcu      120

aacgcaauca cuacuaucuu aaccgcagua acauucuguu uugcauccgg ccaaaacaua      180

acagaagaau uuuaccaauc aacuugcucu gcagucucaa aagguuaucu aucugcauua      240

agaacaggcu gguacaccuc aguaauaacg aucgaacuau caaacaucaa agaaaacaaa      300

uguaauggaa cagacgcaaa aguaaaacua aucaaacaag aacuagacaa auacaaaaac      360

gcaguaaccg aacuccaacu ccucaugcaa aguacaccag caacaaauaa cagagcaaga      420

cgugaacuac cacguuuuau gaauuacacg cucaauaacg caaaaaaaac aaauguuacc      480

cuaucaaaaa aacgaaaaag aagauuccuc ggauuccuac uaggcguagg cucagcaaua      540

gcuucaggag uagcaguauc aaaaguacuc caccucgaag gagaaguaaa caaaaucaaa      600

agcgcucucc ucucaacaaa caaagcaguu guuucacucu caaacggagu aucaguacua      660

accucaaaag uacuugaccu aaaaaauuau auagacaaac aacuauuacc aauaguaaac      720

aaacaaagcu gcuccaucuc caacaucgag acagucauag aauuucaaca aaaaaauaac      780

cgccuauuag aaauaaccag agaauuuuca guaaacgcag gaguaacuac cccaguauca      840

acauauaugu uaacaaacuc agaacuccua agucuaauca acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaaugag caacaaugua caaauaguuc gucaacaauc uuacuccaua      960

augucuauaa uaaaagaaga aguacucgcc uauguagucc aacuaccacu auacggaguc     1020

aucgauacac caugcuggaa acuccacaca uccccacucu guacuacuaa caccaaagaa     1080

gguucaaaua uaugccuaac cagaacagau agagguuggu acugcgauaa ugcaggauca     1140

guauccuuuu ucccccaagc cgaaacaugc aaaguucaau ccaauagagu auuuugugau     1200

acaaugaacu cuuuaacccu cccauccgaa gucaaucuau guaacgucga cauauuuaac     1260

ccaaaauacg auugcaaaau aaugacauca aaaacagacg ucucauccuc aguuauaacg     1320

uccuuaggcg cuauaguauc augcuacggc aaaacaaaau guacagcauc aaacaaaaac     1380

agaggaauca uaaaaacuuu cucuaacggu ugcgacuaug uauccaacaa aggugucgac     1440

acaguauccg uaggcaacac ccuuuacuau guuaauaaac aagaaggaaa aucucuauau     1500

guaaaaggcg aaccaauuau aaauuuuuac gacccccuug ucuuucccuc ugacgaauuu     1560

gacgcuucca uaucacaagu caacgaaaaa aucaaccaau cccucgcauu cauacgcaaa     1620

ucagacgaac uacuacauaa cgucaacgca ggcaaaucca caacaaacau aaugauaacc     1680

acaaucauaa uuguaauaau aguaauacua cuuucucuaa uagcagucgg auuacucuua     1740

uacuguaaag cucgaucaac accagucacc cucucuaaag aucaacuauc cggaaucaac     1800

aacauagcuu ucucaaacua aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  374
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  374
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau acucaaagcc      120

aacgcaauca caaccauacu caccgccguc accuucugcu uugcaucugg ccagaacauc      180

acugaagagu ucuaccaauc cacaugcucc gccguaagca aaggcuaccu auccgcccua      240

cgcaccggcu gguacaccag cguaaucacc auagaacucu ccaauauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa agucaagcua auaaaacaag aacucgacaa auacaaaaac      360

gccguuaccg aacuccagcu acucaugcaa ucgaccccag caaccaacaa ccgugcgaga      420

cgcgaacucc cccgcuucau gaacuacacc cuaaacaacg ccaaaaagac caacguaacu      480

cuauccaaga aacgcaaacg ccgcuuccuc ggauuccucc ucggcgucgg cuccgcaauc      540

gccagcggcg ucgccguuag caaaguccuu caccucgaag gagaaguaaa caaaauuaaa      600

agcgcccucu uauccacaaa caaggccgua guaucccugu caaacggcgu cuccguccuu      660

acauccaaag uccucgaccu caagaacuac auagacaaac agcuacuacc cauuguaaau      720

aaacaaagcu gcucaauuag caacaucgaa accguaaucg aguuccagca gaaaaacaac      780

agacuucucg aaaucacccg cgaguucagc gucaacgccg gcguaaccac cccugucuca      840

acauacaugc uaaccaacag cgaacugcuc ucccucauca acgacaugcc caucaccaac      900

gaccaaaaga aacucaugag caacaacgua caaaucgugc gccaacaguc cuacucaaua      960

augucaauca ucaaagaaga agugcuagca uacgucguac aacuaccacu cuacggcgua     1020

auagauaccc ccugcuggaa gcuccauacc uccccacucu guaccaccaa caccaaagaa     1080

ggcucaaaca ucugccuaac gcgcacagac cguggauggu acugugacaa cgccggcucc     1140

gucuccuucu ucccucaagc cgaaacaugc aaaguccaau ccaacagagu cuucugcgau     1200

accaugaacu cccugacacu cccaagcgaa gucaaccuuu gcaacgucga uaucuuuaac     1260

cccaaauacg acugcaagau caugacauca aaaaccgacg uauccuccuc uguaauaacc     1320

ucccuaggcg caaucguauc augcuacggc aaaaccaaau guaccgccuc caacaaaaau     1380

cgcggcauca ucaaaaccuu cucgaacggc ugcgacuacg ucuccaacaa aggcguagac     1440

acaguuuccg uaggcaacac ccucuacuac gucaauaaac aggaaggcaa gucccucuac     1500

gucaaaggcg aacccaucau caauuucuac gacccccucg uuuuccccuc cgaugaguuc     1560

gacgcaagca ucagccaggu caacgaaaag auaaaccagu cccucgccuu cauccgcaaa     1620

ucagaugaac uccuucacaa cguuaacgca ggcaagagca ccaccaacau caugaucaca     1680

acuauaauca ucgucauaau cgucauccua cucucacuaa ucgccgucgg ucuccuacua     1740

uauuguaaag cccgaucaac accggucaca cucuccaaag accaacucuc cggaaucaac     1800

aauaucgcuu ucucgaacua aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  375
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  375
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagaagcac accagucaca cuaagcaaag aucaacugag ugguauaaau     1800

aauauugcau uuaguaacua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  376
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  376
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  377
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  377
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcagcac gcccgugacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  378
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  378
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  379
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  379
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggucaac acccguuacg uugagcaagg accagcucuc ugggauaaac     1800

aauaucgcuu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  380
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  380
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  381
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  381
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccgguccac ccccguuacg cugagcaagg accagcuuuc uggaauuaac     1800

aauaucgcuu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  382
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  382
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau auuaaaagcu      120

aacgcaauca cuacuaucuu aaccgcagua acauucuguu uugcauccgg ccaaaacaua      180

acagaagaau uuuaccaauc aacuugcucu gcagucucaa aagguuaucu aucugcauua      240

agaacaggcu gguacaccuc aguaauaacg aucgaacuau caaacaucaa agaaaacaaa      300

uguaauggaa cagacgcaaa aguaaaacua aucaaacaag aacuagacaa auacaaaaac      360

gcaguaaccg aacuccaacu ccucaugcaa aguacaccag caacaaauaa cagagcaaga      420

cgugaacuac cacguuuuau gaauuacacg cucaauaacg caaaaaaaac aaauguuacc      480

cuaucaaaaa aacgaaaaag aagauuccuc ggauuccuac uaggcguagg cucagcaaua      540

gcuucaggag uagcaguauc aaaaguacuc caccucgaag gagaaguaaa caaaaucaaa      600

agcgcucucc ucucaacaaa caaagcaguu guuucacucu caaacggagu aucaguacua      660

accucaaaag uacuugaccu aaaaaauuau auagacaaac aacuauuacc aauaguaaac      720

aaacaaagcu gcuccaucuc caacaucgag acagucauag aauuucaaca aaaaaauaac      780

cgccuauuag aaauaaccag agaauuuuca guaaacgcag gaguaacuac cccaguauca      840

acauauaugu uaacaaacuc agaacuccua agucuaauca acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaaugag caacaaugua caaauaguuc gucaacaauc uuacuccaua      960

augucuauaa uaaaagaaga aguacucgcc uauguagucc aacuaccacu auacggaguc     1020

aucgauacac caugcuggaa acuccacaca uccccacucu guacuacuaa caccaaagaa     1080

gguucaaaua uaugccuaac cagaacagau agagguuggu acugcgauaa ugcaggauca     1140

guauccuuuu ucccccaagc cgaaacaugc aaaguucaau ccaauagagu auuuugugau     1200

acaaugaacu cuuuaacccu cccauccgaa gucaaucuau guaacgucga cauauuuaac     1260

ccaaaauacg auugcaaaau aaugacauca aaaacagacg ucucauccuc aguuauaacg     1320

uccuuaggcg cuauaguauc augcuacggc aaaacaaaau guacagcauc aaacaaaaac     1380

agaggaauca uaaaaacuuu cucuaacggu ugcgacuaug uauccaacaa aggugucgac     1440

acaguauccg uaggcaacac ccuuuacuau guuaauaaac aagaaggaaa aucucuauau     1500

guaaaaggcg aaccaauuau aaauuuuuac gacccccuug ucuuucccuc ugacgaauuu     1560

gacgcuucca uaucacaagu caacgaaaaa aucaaccaau cccucgcauu cauacgcaaa     1620

ucagacgaac uacuacauaa cgucaacgca ggcaaaucca caacaaacau aaugauaacc     1680

acaaucauaa uuguaauaau aguaauacua cuuucucuaa uagcagucgg auuacucuua     1740

uacuguaaag cucgaucaac accagucacc cucucuaaag aucaacuauc cggaaucaac     1800

aacauagcuu ucucaaacua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  383
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  383
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau acucaaagcc      120

aacgcaauca caaccauacu caccgccguc accuucugcu uugcaucugg ccagaacauc      180

acugaagagu ucuaccaauc cacaugcucc gccguaagca aaggcuaccu auccgcccua      240

cgcaccggcu gguacaccag cguaaucacc auagaacucu ccaauauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa agucaagcua auaaaacaag aacucgacaa auacaaaaac      360

gccguuaccg aacuccagcu acucaugcaa ucgaccccag caaccaacaa ccgugcgaga      420

cgcgaacucc cccgcuucau gaacuacacc cuaaacaacg ccaaaaagac caacguaacu      480

cuauccaaga aacgcaaacg ccgcuuccuc ggauuccucc ucggcgucgg cuccgcaauc      540

gccagcggcg ucgccguuag caaaguccuu caccucgaag gagaaguaaa caaaauuaaa      600

agcgcccucu uauccacaaa caaggccgua guaucccugu caaacggcgu cuccguccuu      660

acauccaaag uccucgaccu caagaacuac auagacaaac agcuacuacc cauuguaaau      720

aaacaaagcu gcucaauuag caacaucgaa accguaaucg aguuccagca gaaaaacaac      780

agacuucucg aaaucacccg cgaguucagc gucaacgccg gcguaaccac cccugucuca      840

acauacaugc uaaccaacag cgaacugcuc ucccucauca acgacaugcc caucaccaac      900

gaccaaaaga aacucaugag caacaacgua caaaucgugc gccaacaguc cuacucaaua      960

augucaauca ucaaagaaga agugcuagca uacgucguac aacuaccacu cuacggcgua     1020

auagauaccc ccugcuggaa gcuccauacc uccccacucu guaccaccaa caccaaagaa     1080

ggcucaaaca ucugccuaac gcgcacagac cguggauggu acugugacaa cgccggcucc     1140

gucuccuucu ucccucaagc cgaaacaugc aaaguccaau ccaacagagu cuucugcgau     1200

accaugaacu cccugacacu cccaagcgaa gucaaccuuu gcaacgucga uaucuuuaac     1260

cccaaauacg acugcaagau caugacauca aaaaccgacg uauccuccuc uguaauaacc     1320

ucccuaggcg caaucguauc augcuacggc aaaaccaaau guaccgccuc caacaaaaau     1380

cgcggcauca ucaaaaccuu cucgaacggc ugcgacuacg ucuccaacaa aggcguagac     1440

acaguuuccg uaggcaacac ccucuacuac gucaauaaac aggaaggcaa gucccucuac     1500

gucaaaggcg aacccaucau caauuucuac gacccccucg uuuuccccuc cgaugaguuc     1560

gacgcaagca ucagccaggu caacgaaaag auaaaccagu cccucgccuu cauccgcaaa     1620

ucagaugaac uccuucacaa cguuaacgca ggcaagagca ccaccaacau caugaucaca     1680

acuauaauca ucgucauaau cgucauccua cucucacuaa ucgccgucgg ucuccuacua     1740

uauuguaaag cccgaucaac accggucaca cucuccaaag accaacucuc cggaaucaac     1800

aauaucgcuu ucucgaacua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  384
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  384
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gaagcacacc agucacacua     1800

agcaaagauc aacugagugg uauaaauaau auugcauuua guaacuaagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  385
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  385
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  386
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  386
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcagcacgcc cgugacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgccuucu ccaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  387
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  387
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  388
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  388
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggucaacacc cguuacguug     1800

agcaaggacc agcucucugg gauaaacaau aucgcuuucu ccaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  389
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  389
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  390
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  390
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc gguccacccc cguuacgcug     1800

agcaaggacc agcuuucugg aauuaacaau aucgcuuuca gcaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  391
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  391
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauauu aaaagcuaac gcaaucacua cuaucuuaac cgcaguaaca      180

uucuguuuug cauccggcca aaacauaaca gaagaauuuu accaaucaac uugcucugca      240

gucucaaaag guuaucuauc ugcauuaaga acaggcuggu acaccucagu aauaacgauc      300

gaacuaucaa acaucaaaga aaacaaaugu aauggaacag acgcaaaagu aaaacuaauc      360

aaacaagaac uagacaaaua caaaaacgca guaaccgaac uccaacuccu caugcaaagu      420

acaccagcaa caaauaacag agcaagacgu gaacuaccac guuuuaugaa uuacacgcuc      480

aauaacgcaa aaaaaacaaa uguuacccua ucaaaaaaac gaaaaagaag auuccucgga      540

uuccuacuag gcguaggcuc agcaauagcu ucaggaguag caguaucaaa aguacuccac      600

cucgaaggag aaguaaacaa aaucaaaagc gcucuccucu caacaaacaa agcaguuguu      660

ucacucucaa acggaguauc aguacuaacc ucaaaaguac uugaccuaaa aaauuauaua      720

gacaaacaac uauuaccaau aguaaacaaa caaagcugcu ccaucuccaa caucgagaca      780

gucauagaau uucaacaaaa aaauaaccgc cuauuagaaa uaaccagaga auuuucagua      840

aacgcaggag uaacuacccc aguaucaaca uauauguuaa caaacucaga acuccuaagu      900

cuaaucaacg acaugccaau aaccaacgac caaaaaaaac uaaugagcaa caauguacaa      960

auaguucguc aacaaucuua cuccauaaug ucuauaauaa aagaagaagu acucgccuau     1020

guaguccaac uaccacuaua cggagucauc gauacaccau gcuggaaacu ccacacaucc     1080

ccacucugua cuacuaacac caaagaaggu ucaaauauau gccuaaccag aacagauaga     1140

gguugguacu gcgauaaugc aggaucagua uccuuuuucc cccaagccga aacaugcaaa     1200

guucaaucca auagaguauu uugugauaca augaacucuu uaacccuccc auccgaaguc     1260

aaucuaugua acgucgacau auuuaaccca aaauacgauu gcaaaauaau gacaucaaaa     1320

acagacgucu cauccucagu uauaacgucc uuaggcgcua uaguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa caaaaacaga ggaaucauaa aaacuuucuc uaacgguugc     1440

gacuauguau ccaacaaagg ugucgacaca guauccguag gcaacacccu uuacuauguu     1500

aauaaacaag aaggaaaauc ucuauaugua aaaggcgaac caauuauaaa uuuuuacgac     1560

ccccuugucu uucccucuga cgaauuugac gcuuccauau cacaagucaa cgaaaaaauc     1620

aaccaauccc ucgcauucau acgcaaauca gacgaacuac uacauaacgu caacgcaggc     1680

aaauccacaa caaacauaau gauaaccaca aucauaauug uaauaauagu aauacuacuu     1740

ucucuaauag cagucggauu acucuuauac uguaaagcuc gaucaacacc agucacccuc     1800

ucuaaagauc aacuauccgg aaucaacaac auagcuuucu caaacuaagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  392
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  392
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauacu caaagccaac gcaaucacaa ccauacucac cgccgucacc      180

uucugcuuug caucuggcca gaacaucacu gaagaguucu accaauccac augcuccgcc      240

guaagcaaag gcuaccuauc cgcccuacgc accggcuggu acaccagcgu aaucaccaua      300

gaacucucca auauaaaaga aaacaaaugc aacggcaccg acgcaaaagu caagcuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc guuaccgaac uccagcuacu caugcaaucg      420

accccagcaa ccaacaaccg ugcgagacgc gaacuccccc gcuucaugaa cuacacccua      480

aacaacgcca aaaagaccaa cguaacucua uccaagaaac gcaaacgccg cuuccucgga      540

uuccuccucg gcgucggcuc cgcaaucgcc agcggcgucg ccguuagcaa aguccuucac      600

cucgaaggag aaguaaacaa aauuaaaagc gcccucuuau ccacaaacaa ggccguagua      660

ucccugucaa acggcgucuc cguccuuaca uccaaagucc ucgaccucaa gaacuacaua      720

gacaaacagc uacuacccau uguaaauaaa caaagcugcu caauuagcaa caucgaaacc      780

guaaucgagu uccagcagaa aaacaacaga cuucucgaaa ucacccgcga guucagcguc      840

aacgccggcg uaaccacccc ugucucaaca uacaugcuaa ccaacagcga acugcucucc      900

cucaucaacg acaugcccau caccaacgac caaaagaaac ucaugagcaa caacguacaa      960

aucgugcgcc aacaguccua cucaauaaug ucaaucauca aagaagaagu gcuagcauac     1020

gucguacaac uaccacucua cggcguaaua gauacccccu gcuggaagcu ccauaccucc     1080

ccacucugua ccaccaacac caaagaaggc ucaaacaucu gccuaacgcg cacagaccgu     1140

ggaugguacu gugacaacgc cggcuccguc uccuucuucc cucaagccga aacaugcaaa     1200

guccaaucca acagagucuu cugcgauacc augaacuccc ugacacuccc aagcgaaguc     1260

aaccuuugca acgucgauau cuuuaacccc aaauacgacu gcaagaucau gacaucaaaa     1320

accgacguau ccuccucugu aauaaccucc cuaggcgcaa ucguaucaug cuacggcaaa     1380

accaaaugua ccgccuccaa caaaaaucgc ggcaucauca aaaccuucuc gaacggcugc     1440

gacuacgucu ccaacaaagg cguagacaca guuuccguag gcaacacccu cuacuacguc     1500

aauaaacagg aaggcaaguc ccucuacguc aaaggcgaac ccaucaucaa uuucuacgac     1560

ccccucguuu uccccuccga ugaguucgac gcaagcauca gccaggucaa cgaaaagaua     1620

aaccaguccc ucgccuucau ccgcaaauca gaugaacucc uucacaacgu uaacgcaggc     1680

aagagcacca ccaacaucau gaucacaacu auaaucaucg ucauaaucgu cauccuacuc     1740

ucacuaaucg ccgucggucu ccuacuauau uguaaagccc gaucaacacc ggucacacuc     1800

uccaaagacc aacucuccgg aaucaacaau aucgcuuucu cgaacuaagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  393
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  393
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaag cacaccaguc acacuaagca aagaucaacu gagugguaua     1800

aauaauauug cauuuaguaa cuaaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  394
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  394
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  395
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  395
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcag cacgcccgug acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  396
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  396
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  397
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  397
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccagguc aacacccguu acguugagca aggaccagcu cucugggaua     1800

aacaauaucg cuuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  398
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  398
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  399
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  399
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccgguc cacccccguu acgcugagca aggaccagcu uucuggaauu     1800

aacaauaucg cuuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  400
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  400
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauauuaaaa      120

gcuaacgcaa ucacuacuau cuuaaccgca guaacauucu guuuugcauc cggccaaaac      180

auaacagaag aauuuuacca aucaacuugc ucugcagucu caaaagguua ucuaucugca      240

uuaagaacag gcugguacac cucaguaaua acgaucgaac uaucaaacau caaagaaaac      300

aaauguaaug gaacagacgc aaaaguaaaa cuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguaa ccgaacucca acuccucaug caaaguacac cagcaacaaa uaacagagca      420

agacgugaac uaccacguuu uaugaauuac acgcucaaua acgcaaaaaa aacaaauguu      480

acccuaucaa aaaaacgaaa aagaagauuc cucggauucc uacuaggcgu aggcucagca      540

auagcuucag gaguagcagu aucaaaagua cuccaccucg aaggagaagu aaacaaaauc      600

aaaagcgcuc uccucucaac aaacaaagca guuguuucac ucucaaacgg aguaucagua      660

cuaaccucaa aaguacuuga ccuaaaaaau uauauagaca aacaacuauu accaauagua      720

aacaaacaaa gcugcuccau cuccaacauc gagacaguca uagaauuuca acaaaaaaau      780

aaccgccuau uagaaauaac cagagaauuu ucaguaaacg caggaguaac uaccccagua      840

ucaacauaua uguuaacaaa cucagaacuc cuaagucuaa ucaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gagcaacaau guacaaauag uucgucaaca aucuuacucc      960

auaaugucua uaauaaaaga agaaguacuc gccuauguag uccaacuacc acuauacgga     1020

gucaucgaua caccaugcug gaaacuccac acauccccac ucuguacuac uaacaccaaa     1080

gaagguucaa auauaugccu aaccagaaca gauagagguu gguacugcga uaaugcagga     1140

ucaguauccu uuuuccccca agccgaaaca ugcaaaguuc aauccaauag aguauuuugu     1200

gauacaauga acucuuuaac ccucccaucc gaagucaauc uauguaacgu cgacauauuu     1260

aacccaaaau acgauugcaa aauaaugaca ucaaaaacag acgucucauc cucaguuaua     1320

acguccuuag gcgcuauagu aucaugcuac ggcaaaacaa aauguacagc aucaaacaaa     1380

aacagaggaa ucauaaaaac uuucucuaac gguugcgacu auguauccaa caaagguguc     1440

gacacaguau ccguaggcaa cacccuuuac uauguuaaua aacaagaagg aaaaucucua     1500

uauguaaaag gcgaaccaau uauaaauuuu uacgaccccc uugucuuucc cucugacgaa     1560

uuugacgcuu ccauaucaca agucaacgaa aaaaucaacc aaucccucgc auucauacgc     1620

aaaucagacg aacuacuaca uaacgucaac gcaggcaaau ccacaacaaa cauaaugaua     1680

accacaauca uaauuguaau aauaguaaua cuacuuucuc uaauagcagu cggauuacuc     1740

uuauacugua aagcucgauc aacaccaguc acccucucua aagaucaacu auccggaauc     1800

aacaacauag cuuucucaaa cuaaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  401
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  401
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauacucaaa      120

gccaacgcaa ucacaaccau acucaccgcc gucaccuucu gcuuugcauc uggccagaac      180

aucacugaag aguucuacca auccacaugc uccgccguaa gcaaaggcua ccuauccgcc      240

cuacgcaccg gcugguacac cagcguaauc accauagaac ucuccaauau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaagucaag cuaauaaaac aagaacucga caaauacaaa      360

aacgccguua ccgaacucca gcuacucaug caaucgaccc cagcaaccaa caaccgugcg      420

agacgcgaac ucccccgcuu caugaacuac acccuaaaca acgccaaaaa gaccaacgua      480

acucuaucca agaaacgcaa acgccgcuuc cucggauucc uccucggcgu cggcuccgca      540

aucgccagcg gcgucgccgu uagcaaaguc cuucaccucg aaggagaagu aaacaaaauu      600

aaaagcgccc ucuuauccac aaacaaggcc guaguauccc ugucaaacgg cgucuccguc      660

cuuacaucca aaguccucga ccucaagaac uacauagaca aacagcuacu acccauugua      720

aauaaacaaa gcugcucaau uagcaacauc gaaaccguaa ucgaguucca gcagaaaaac      780

aacagacuuc ucgaaaucac ccgcgaguuc agcgucaacg ccggcguaac caccccuguc      840

ucaacauaca ugcuaaccaa cagcgaacug cucucccuca ucaacgacau gcccaucacc      900

aacgaccaaa agaaacucau gagcaacaac guacaaaucg ugcgccaaca guccuacuca      960

auaaugucaa ucaucaaaga agaagugcua gcauacgucg uacaacuacc acucuacggc     1020

guaauagaua cccccugcug gaagcuccau accuccccac ucuguaccac caacaccaaa     1080

gaaggcucaa acaucugccu aacgcgcaca gaccguggau gguacuguga caacgccggc     1140

uccgucuccu ucuucccuca agccgaaaca ugcaaagucc aauccaacag agucuucugc     1200

gauaccauga acucccugac acucccaagc gaagucaacc uuugcaacgu cgauaucuuu     1260

aaccccaaau acgacugcaa gaucaugaca ucaaaaaccg acguauccuc cucuguaaua     1320

accucccuag gcgcaaucgu aucaugcuac ggcaaaacca aauguaccgc cuccaacaaa     1380

aaucgcggca ucaucaaaac cuucucgaac ggcugcgacu acgucuccaa caaaggcgua     1440

gacacaguuu ccguaggcaa cacccucuac uacgucaaua aacaggaagg caagucccuc     1500

uacgucaaag gcgaacccau caucaauuuc uacgaccccc ucguuuuccc cuccgaugag     1560

uucgacgcaa gcaucagcca ggucaacgaa aagauaaacc agucccucgc cuucauccgc     1620

aaaucagaug aacuccuuca caacguuaac gcaggcaaga gcaccaccaa caucaugauc     1680

acaacuauaa ucaucgucau aaucgucauc cuacucucac uaaucgccgu cggucuccua     1740

cuauauugua aagcccgauc aacaccgguc acacucucca aagaccaacu cuccggaauc     1800

aacaauaucg cuuucucgaa cuaaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  402
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  402
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaag cacaccaguc acacuaagca aagaucaacu gagugguaua     1800

aauaauauug cauuuaguaa cuaaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  403
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  403
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  404
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  404
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcag cacgcccgug acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  405
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  405
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  406
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  406
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccagguc aacacccguu acguugagca aggaccagcu cucugggaua     1800

aacaauaucg cuuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  407
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  407
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  408
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  408
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccgguc cacccccguu acgcugagca aggaccagcu uucuggaauu     1800

aacaauaucg cuuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  409
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  409
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauauuaaaa      120

gcuaacgcaa ucacuacuau cuuaaccgca guaacauucu guuuugcauc cggccaaaac      180

auaacagaag aauuuuacca aucaacuugc ucugcagucu caaaagguua ucuaucugca      240

uuaagaacag gcugguacac cucaguaaua acgaucgaac uaucaaacau caaagaaaac      300

aaauguaaug gaacagacgc aaaaguaaaa cuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguaa ccgaacucca acuccucaug caaaguacac cagcaacaaa uaacagagca      420

agacgugaac uaccacguuu uaugaauuac acgcucaaua acgcaaaaaa aacaaauguu      480

acccuaucaa aaaaacgaaa aagaagauuc cucggauucc uacuaggcgu aggcucagca      540

auagcuucag gaguagcagu aucaaaagua cuccaccucg aaggagaagu aaacaaaauc      600

aaaagcgcuc uccucucaac aaacaaagca guuguuucac ucucaaacgg aguaucagua      660

cuaaccucaa aaguacuuga ccuaaaaaau uauauagaca aacaacuauu accaauagua      720

aacaaacaaa gcugcuccau cuccaacauc gagacaguca uagaauuuca acaaaaaaau      780

aaccgccuau uagaaauaac cagagaauuu ucaguaaacg caggaguaac uaccccagua      840

ucaacauaua uguuaacaaa cucagaacuc cuaagucuaa ucaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gagcaacaau guacaaauag uucgucaaca aucuuacucc      960

auaaugucua uaauaaaaga agaaguacuc gccuauguag uccaacuacc acuauacgga     1020

gucaucgaua caccaugcug gaaacuccac acauccccac ucuguacuac uaacaccaaa     1080

gaagguucaa auauaugccu aaccagaaca gauagagguu gguacugcga uaaugcagga     1140

ucaguauccu uuuuccccca agccgaaaca ugcaaaguuc aauccaauag aguauuuugu     1200

gauacaauga acucuuuaac ccucccaucc gaagucaauc uauguaacgu cgacauauuu     1260

aacccaaaau acgauugcaa aauaaugaca ucaaaaacag acgucucauc cucaguuaua     1320

acguccuuag gcgcuauagu aucaugcuac ggcaaaacaa aauguacagc aucaaacaaa     1380

aacagaggaa ucauaaaaac uuucucuaac gguugcgacu auguauccaa caaagguguc     1440

gacacaguau ccguaggcaa cacccuuuac uauguuaaua aacaagaagg aaaaucucua     1500

uauguaaaag gcgaaccaau uauaaauuuu uacgaccccc uugucuuucc cucugacgaa     1560

uuugacgcuu ccauaucaca agucaacgaa aaaaucaacc aaucccucgc auucauacgc     1620

aaaucagacg aacuacuaca uaacgucaac gcaggcaaau ccacaacaaa cauaaugaua     1680

accacaauca uaauuguaau aauaguaaua cuacuuucuc uaauagcagu cggauuacuc     1740

uuauacugua aagcucgauc aacaccaguc acccucucua aagaucaacu auccggaauc     1800

aacaacauag cuuucucaaa cuaaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  410
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  410
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauacucaaa      120

gccaacgcaa ucacaaccau acucaccgcc gucaccuucu gcuuugcauc uggccagaac      180

aucacugaag aguucuacca auccacaugc uccgccguaa gcaaaggcua ccuauccgcc      240

cuacgcaccg gcugguacac cagcguaauc accauagaac ucuccaauau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaagucaag cuaauaaaac aagaacucga caaauacaaa      360

aacgccguua ccgaacucca gcuacucaug caaucgaccc cagcaaccaa caaccgugcg      420

agacgcgaac ucccccgcuu caugaacuac acccuaaaca acgccaaaaa gaccaacgua      480

acucuaucca agaaacgcaa acgccgcuuc cucggauucc uccucggcgu cggcuccgca      540

aucgccagcg gcgucgccgu uagcaaaguc cuucaccucg aaggagaagu aaacaaaauu      600

aaaagcgccc ucuuauccac aaacaaggcc guaguauccc ugucaaacgg cgucuccguc      660

cuuacaucca aaguccucga ccucaagaac uacauagaca aacagcuacu acccauugua      720

aauaaacaaa gcugcucaau uagcaacauc gaaaccguaa ucgaguucca gcagaaaaac      780

aacagacuuc ucgaaaucac ccgcgaguuc agcgucaacg ccggcguaac caccccuguc      840

ucaacauaca ugcuaaccaa cagcgaacug cucucccuca ucaacgacau gcccaucacc      900

aacgaccaaa agaaacucau gagcaacaac guacaaaucg ugcgccaaca guccuacuca      960

auaaugucaa ucaucaaaga agaagugcua gcauacgucg uacaacuacc acucuacggc     1020

guaauagaua cccccugcug gaagcuccau accuccccac ucuguaccac caacaccaaa     1080

gaaggcucaa acaucugccu aacgcgcaca gaccguggau gguacuguga caacgccggc     1140

uccgucuccu ucuucccuca agccgaaaca ugcaaagucc aauccaacag agucuucugc     1200

gauaccauga acucccugac acucccaagc gaagucaacc uuugcaacgu cgauaucuuu     1260

aaccccaaau acgacugcaa gaucaugaca ucaaaaaccg acguauccuc cucuguaaua     1320

accucccuag gcgcaaucgu aucaugcuac ggcaaaacca aauguaccgc cuccaacaaa     1380

aaucgcggca ucaucaaaac cuucucgaac ggcugcgacu acgucuccaa caaaggcgua     1440

gacacaguuu ccguaggcaa cacccucuac uacgucaaua aacaggaagg caagucccuc     1500

uacgucaaag gcgaacccau caucaauuuc uacgaccccc ucguuuuccc cuccgaugag     1560

uucgacgcaa gcaucagcca ggucaacgaa aagauaaacc agucccucgc cuucauccgc     1620

aaaucagaug aacuccuuca caacguuaac gcaggcaaga gcaccaccaa caucaugauc     1680

acaacuauaa ucaucgucau aaucgucauc cuacucucac uaaucgccgu cggucuccua     1740

cuauauugua aagcccgauc aacaccgguc acacucucca aagaccaacu cuccggaauc     1800

aacaauaucg cuuucucgaa cuaaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  411
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  411
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaag cacaccaguc acacuaagca aagaucaacu gagugguaua     1800

aauaauauug cauuuaguaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  412
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  412
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  413
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  413
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcag cacgcccgug acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  414
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  414
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  415
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  415
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccagguc aacacccguu acguugagca aggaccagcu cucugggaua     1800

aacaauaucg cuuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  416
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  416
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  417
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  417
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccgguc cacccccguu acgcugagca aggaccagcu uucuggaauu     1800

aacaauaucg cuuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  418
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  418
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauauuaaaa      120

gcuaacgcaa ucacuacuau cuuaaccgca guaacauucu guuuugcauc cggccaaaac      180

auaacagaag aauuuuacca aucaacuugc ucugcagucu caaaagguua ucuaucugca      240

uuaagaacag gcugguacac cucaguaaua acgaucgaac uaucaaacau caaagaaaac      300

aaauguaaug gaacagacgc aaaaguaaaa cuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguaa ccgaacucca acuccucaug caaaguacac cagcaacaaa uaacagagca      420

agacgugaac uaccacguuu uaugaauuac acgcucaaua acgcaaaaaa aacaaauguu      480

acccuaucaa aaaaacgaaa aagaagauuc cucggauucc uacuaggcgu aggcucagca      540

auagcuucag gaguagcagu aucaaaagua cuccaccucg aaggagaagu aaacaaaauc      600

aaaagcgcuc uccucucaac aaacaaagca guuguuucac ucucaaacgg aguaucagua      660

cuaaccucaa aaguacuuga ccuaaaaaau uauauagaca aacaacuauu accaauagua      720

aacaaacaaa gcugcuccau cuccaacauc gagacaguca uagaauuuca acaaaaaaau      780

aaccgccuau uagaaauaac cagagaauuu ucaguaaacg caggaguaac uaccccagua      840

ucaacauaua uguuaacaaa cucagaacuc cuaagucuaa ucaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gagcaacaau guacaaauag uucgucaaca aucuuacucc      960

auaaugucua uaauaaaaga agaaguacuc gccuauguag uccaacuacc acuauacgga     1020

gucaucgaua caccaugcug gaaacuccac acauccccac ucuguacuac uaacaccaaa     1080

gaagguucaa auauaugccu aaccagaaca gauagagguu gguacugcga uaaugcagga     1140

ucaguauccu uuuuccccca agccgaaaca ugcaaaguuc aauccaauag aguauuuugu     1200

gauacaauga acucuuuaac ccucccaucc gaagucaauc uauguaacgu cgacauauuu     1260

aacccaaaau acgauugcaa aauaaugaca ucaaaaacag acgucucauc cucaguuaua     1320

acguccuuag gcgcuauagu aucaugcuac ggcaaaacaa aauguacagc aucaaacaaa     1380

aacagaggaa ucauaaaaac uuucucuaac gguugcgacu auguauccaa caaagguguc     1440

gacacaguau ccguaggcaa cacccuuuac uauguuaaua aacaagaagg aaaaucucua     1500

uauguaaaag gcgaaccaau uauaaauuuu uacgaccccc uugucuuucc cucugacgaa     1560

uuugacgcuu ccauaucaca agucaacgaa aaaaucaacc aaucccucgc auucauacgc     1620

aaaucagacg aacuacuaca uaacgucaac gcaggcaaau ccacaacaaa cauaaugaua     1680

accacaauca uaauuguaau aauaguaaua cuacuuucuc uaauagcagu cggauuacuc     1740

uuauacugua aagcucgauc aacaccaguc acccucucua aagaucaacu auccggaauc     1800

aacaacauag cuuucucaaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  419
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  419
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauacucaaa      120

gccaacgcaa ucacaaccau acucaccgcc gucaccuucu gcuuugcauc uggccagaac      180

aucacugaag aguucuacca auccacaugc uccgccguaa gcaaaggcua ccuauccgcc      240

cuacgcaccg gcugguacac cagcguaauc accauagaac ucuccaauau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaagucaag cuaauaaaac aagaacucga caaauacaaa      360

aacgccguua ccgaacucca gcuacucaug caaucgaccc cagcaaccaa caaccgugcg      420

agacgcgaac ucccccgcuu caugaacuac acccuaaaca acgccaaaaa gaccaacgua      480

acucuaucca agaaacgcaa acgccgcuuc cucggauucc uccucggcgu cggcuccgca      540

aucgccagcg gcgucgccgu uagcaaaguc cuucaccucg aaggagaagu aaacaaaauu      600

aaaagcgccc ucuuauccac aaacaaggcc guaguauccc ugucaaacgg cgucuccguc      660

cuuacaucca aaguccucga ccucaagaac uacauagaca aacagcuacu acccauugua      720

aauaaacaaa gcugcucaau uagcaacauc gaaaccguaa ucgaguucca gcagaaaaac      780

aacagacuuc ucgaaaucac ccgcgaguuc agcgucaacg ccggcguaac caccccuguc      840

ucaacauaca ugcuaaccaa cagcgaacug cucucccuca ucaacgacau gcccaucacc      900

aacgaccaaa agaaacucau gagcaacaac guacaaaucg ugcgccaaca guccuacuca      960

auaaugucaa ucaucaaaga agaagugcua gcauacgucg uacaacuacc acucuacggc     1020

guaauagaua cccccugcug gaagcuccau accuccccac ucuguaccac caacaccaaa     1080

gaaggcucaa acaucugccu aacgcgcaca gaccguggau gguacuguga caacgccggc     1140

uccgucuccu ucuucccuca agccgaaaca ugcaaagucc aauccaacag agucuucugc     1200

gauaccauga acucccugac acucccaagc gaagucaacc uuugcaacgu cgauaucuuu     1260

aaccccaaau acgacugcaa gaucaugaca ucaaaaaccg acguauccuc cucuguaaua     1320

accucccuag gcgcaaucgu aucaugcuac ggcaaaacca aauguaccgc cuccaacaaa     1380

aaucgcggca ucaucaaaac cuucucgaac ggcugcgacu acgucuccaa caaaggcgua     1440

gacacaguuu ccguaggcaa cacccucuac uacgucaaua aacaggaagg caagucccuc     1500

uacgucaaag gcgaacccau caucaauuuc uacgaccccc ucguuuuccc cuccgaugag     1560

uucgacgcaa gcaucagcca ggucaacgaa aagauaaacc agucccucgc cuucauccgc     1620

aaaucagaug aacuccuuca caacguuaac gcaggcaaga gcaccaccaa caucaugauc     1680

acaacuauaa ucaucgucau aaucgucauc cuacucucac uaaucgccgu cggucuccua     1740

cuauauugua aagcccgauc aacaccgguc acacucucca aagaccaacu cuccggaauc     1800

aacaauaucg cuuucucgaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  420
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  420
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaag cacaccaguc acacuaagca aagaucaacu gagugguaua     1800

aauaauauug cauuuaguaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  421
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  421
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  422
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  422
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcag cacgcccgug acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  423
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  423
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  424
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  424
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccagguc aacacccguu acguugagca aggaccagcu cucugggaua     1800

aacaauaucg cuuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  425
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  425
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  426
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  426
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccgguc cacccccguu acgcugagca aggaccagcu uucuggaauu     1800

aacaauaucg cuuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  427
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  427
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauauuaaaa      120

gcuaacgcaa ucacuacuau cuuaaccgca guaacauucu guuuugcauc cggccaaaac      180

auaacagaag aauuuuacca aucaacuugc ucugcagucu caaaagguua ucuaucugca      240

uuaagaacag gcugguacac cucaguaaua acgaucgaac uaucaaacau caaagaaaac      300

aaauguaaug gaacagacgc aaaaguaaaa cuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguaa ccgaacucca acuccucaug caaaguacac cagcaacaaa uaacagagca      420

agacgugaac uaccacguuu uaugaauuac acgcucaaua acgcaaaaaa aacaaauguu      480

acccuaucaa aaaaacgaaa aagaagauuc cucggauucc uacuaggcgu aggcucagca      540

auagcuucag gaguagcagu aucaaaagua cuccaccucg aaggagaagu aaacaaaauc      600

aaaagcgcuc uccucucaac aaacaaagca guuguuucac ucucaaacgg aguaucagua      660

cuaaccucaa aaguacuuga ccuaaaaaau uauauagaca aacaacuauu accaauagua      720

aacaaacaaa gcugcuccau cuccaacauc gagacaguca uagaauuuca acaaaaaaau      780

aaccgccuau uagaaauaac cagagaauuu ucaguaaacg caggaguaac uaccccagua      840

ucaacauaua uguuaacaaa cucagaacuc cuaagucuaa ucaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gagcaacaau guacaaauag uucgucaaca aucuuacucc      960

auaaugucua uaauaaaaga agaaguacuc gccuauguag uccaacuacc acuauacgga     1020

gucaucgaua caccaugcug gaaacuccac acauccccac ucuguacuac uaacaccaaa     1080

gaagguucaa auauaugccu aaccagaaca gauagagguu gguacugcga uaaugcagga     1140

ucaguauccu uuuuccccca agccgaaaca ugcaaaguuc aauccaauag aguauuuugu     1200

gauacaauga acucuuuaac ccucccaucc gaagucaauc uauguaacgu cgacauauuu     1260

aacccaaaau acgauugcaa aauaaugaca ucaaaaacag acgucucauc cucaguuaua     1320

acguccuuag gcgcuauagu aucaugcuac ggcaaaacaa aauguacagc aucaaacaaa     1380

aacagaggaa ucauaaaaac uuucucuaac gguugcgacu auguauccaa caaagguguc     1440

gacacaguau ccguaggcaa cacccuuuac uauguuaaua aacaagaagg aaaaucucua     1500

uauguaaaag gcgaaccaau uauaaauuuu uacgaccccc uugucuuucc cucugacgaa     1560

uuugacgcuu ccauaucaca agucaacgaa aaaaucaacc aaucccucgc auucauacgc     1620

aaaucagacg aacuacuaca uaacgucaac gcaggcaaau ccacaacaaa cauaaugaua     1680

accacaauca uaauuguaau aauaguaaua cuacuuucuc uaauagcagu cggauuacuc     1740

uuauacugua aagcucgauc aacaccaguc acccucucua aagaucaacu auccggaauc     1800

aacaacauag cuuucucaaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  428
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  428
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauacucaaa      120

gccaacgcaa ucacaaccau acucaccgcc gucaccuucu gcuuugcauc uggccagaac      180

aucacugaag aguucuacca auccacaugc uccgccguaa gcaaaggcua ccuauccgcc      240

cuacgcaccg gcugguacac cagcguaauc accauagaac ucuccaauau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaagucaag cuaauaaaac aagaacucga caaauacaaa      360

aacgccguua ccgaacucca gcuacucaug caaucgaccc cagcaaccaa caaccgugcg      420

agacgcgaac ucccccgcuu caugaacuac acccuaaaca acgccaaaaa gaccaacgua      480

acucuaucca agaaacgcaa acgccgcuuc cucggauucc uccucggcgu cggcuccgca      540

aucgccagcg gcgucgccgu uagcaaaguc cuucaccucg aaggagaagu aaacaaaauu      600

aaaagcgccc ucuuauccac aaacaaggcc guaguauccc ugucaaacgg cgucuccguc      660

cuuacaucca aaguccucga ccucaagaac uacauagaca aacagcuacu acccauugua      720

aauaaacaaa gcugcucaau uagcaacauc gaaaccguaa ucgaguucca gcagaaaaac      780

aacagacuuc ucgaaaucac ccgcgaguuc agcgucaacg ccggcguaac caccccuguc      840

ucaacauaca ugcuaaccaa cagcgaacug cucucccuca ucaacgacau gcccaucacc      900

aacgaccaaa agaaacucau gagcaacaac guacaaaucg ugcgccaaca guccuacuca      960

auaaugucaa ucaucaaaga agaagugcua gcauacgucg uacaacuacc acucuacggc     1020

guaauagaua cccccugcug gaagcuccau accuccccac ucuguaccac caacaccaaa     1080

gaaggcucaa acaucugccu aacgcgcaca gaccguggau gguacuguga caacgccggc     1140

uccgucuccu ucuucccuca agccgaaaca ugcaaagucc aauccaacag agucuucugc     1200

gauaccauga acucccugac acucccaagc gaagucaacc uuugcaacgu cgauaucuuu     1260

aaccccaaau acgacugcaa gaucaugaca ucaaaaaccg acguauccuc cucuguaaua     1320

accucccuag gcgcaaucgu aucaugcuac ggcaaaacca aauguaccgc cuccaacaaa     1380

aaucgcggca ucaucaaaac cuucucgaac ggcugcgacu acgucuccaa caaaggcgua     1440

gacacaguuu ccguaggcaa cacccucuac uacgucaaua aacaggaagg caagucccuc     1500

uacgucaaag gcgaacccau caucaauuuc uacgaccccc ucguuuuccc cuccgaugag     1560

uucgacgcaa gcaucagcca ggucaacgaa aagauaaacc agucccucgc cuucauccgc     1620

aaaucagaug aacuccuuca caacguuaac gcaggcaaga gcaccaccaa caucaugauc     1680

acaacuauaa ucaucgucau aaucgucauc cuacucucac uaaucgccgu cggucuccua     1740

cuauauugua aagcccgauc aacaccgguc acacucucca aagaccaacu cuccggaauc     1800

aacaauaucg cuuucucgaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  429
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  429
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agaagcacac cagucacacu aagcaaagau     1860

caacugagug guauaaauaa uauugcauuu aguaacuaag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  430
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  430
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  431
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  431
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcagcacgc ccgugacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc uccaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  432
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  432
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  433
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  433
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggucaacac ccguuacguu gagcaaggac     1860

cagcucucug ggauaaacaa uaucgcuuuc uccaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  434
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  434
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  435
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  435
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cgguccaccc ccguuacgcu gagcaaggac     1860

cagcuuucug gaauuaacaa uaucgcuuuc agcaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  436
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  436
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauau uaaaagcuaa cgcaaucacu acuaucuuaa ccgcaguaac auucuguuuu      240

gcauccggcc aaaacauaac agaagaauuu uaccaaucaa cuugcucugc agucucaaaa      300

gguuaucuau cugcauuaag aacaggcugg uacaccucag uaauaacgau cgaacuauca      360

aacaucaaag aaaacaaaug uaauggaaca gacgcaaaag uaaaacuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguaaccgaa cuccaacucc ucaugcaaag uacaccagca      480

acaaauaaca gagcaagacg ugaacuacca cguuuuauga auuacacgcu caauaacgca      540

aaaaaaacaa auguuacccu aucaaaaaaa cgaaaaagaa gauuccucgg auuccuacua      600

ggcguaggcu cagcaauagc uucaggagua gcaguaucaa aaguacucca ccucgaagga      660

gaaguaaaca aaaucaaaag cgcucuccuc ucaacaaaca aagcaguugu uucacucuca      720

aacggaguau caguacuaac cucaaaagua cuugaccuaa aaaauuauau agacaaacaa      780

cuauuaccaa uaguaaacaa acaaagcugc uccaucucca acaucgagac agucauagaa      840

uuucaacaaa aaaauaaccg ccuauuagaa auaaccagag aauuuucagu aaacgcagga      900

guaacuaccc caguaucaac auauauguua acaaacucag aacuccuaag ucuaaucaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugagca acaauguaca aauaguucgu     1020

caacaaucuu acuccauaau gucuauaaua aaagaagaag uacucgccua uguaguccaa     1080

cuaccacuau acggagucau cgauacacca ugcuggaaac uccacacauc cccacucugu     1140

acuacuaaca ccaaagaagg uucaaauaua ugccuaacca gaacagauag agguugguac     1200

ugcgauaaug caggaucagu auccuuuuuc ccccaagccg aaacaugcaa aguucaaucc     1260

aauagaguau uuugugauac aaugaacucu uuaacccucc cauccgaagu caaucuaugu     1320

aacgucgaca uauuuaaccc aaaauacgau ugcaaaauaa ugacaucaaa aacagacguc     1380

ucauccucag uuauaacguc cuuaggcgcu auaguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa acaaaaacag aggaaucaua aaaacuuucu cuaacgguug cgacuaugua     1500

uccaacaaag gugucgacac aguauccgua ggcaacaccc uuuacuaugu uaauaaacaa     1560

gaaggaaaau cucuauaugu aaaaggcgaa ccaauuauaa auuuuuacga cccccuuguc     1620

uuucccucug acgaauuuga cgcuuccaua ucacaaguca acgaaaaaau caaccaaucc     1680

cucgcauuca uacgcaaauc agacgaacua cuacauaacg ucaacgcagg caaauccaca     1740

acaaacauaa ugauaaccac aaucauaauu guaauaauag uaauacuacu uucucuaaua     1800

gcagucggau uacucuuaua cuguaaagcu cgaucaacac cagucacccu cucuaaagau     1860

caacuauccg gaaucaacaa cauagcuuuc ucaaacuaag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  437
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  437
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucauac ucaaagccaa cgcaaucaca accauacuca ccgccgucac cuucugcuuu      240

gcaucuggcc agaacaucac ugaagaguuc uaccaaucca caugcuccgc cguaagcaaa      300

ggcuaccuau ccgcccuacg caccggcugg uacaccagcg uaaucaccau agaacucucc      360

aauauaaaag aaaacaaaug caacggcacc gacgcaaaag ucaagcuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cguuaccgaa cuccagcuac ucaugcaauc gaccccagca      480

accaacaacc gugcgagacg cgaacucccc cgcuucauga acuacacccu aaacaacgcc      540

aaaaagacca acguaacucu auccaagaaa cgcaaacgcc gcuuccucgg auuccuccuc      600

ggcgucggcu ccgcaaucgc cagcggcguc gccguuagca aaguccuuca ccucgaagga      660

gaaguaaaca aaauuaaaag cgcccucuua uccacaaaca aggccguagu aucccuguca      720

aacggcgucu ccguccuuac auccaaaguc cucgaccuca agaacuacau agacaaacag      780

cuacuaccca uuguaaauaa acaaagcugc ucaauuagca acaucgaaac cguaaucgag      840

uuccagcaga aaaacaacag acuucucgaa aucacccgcg aguucagcgu caacgccggc      900

guaaccaccc cugucucaac auacaugcua accaacagcg aacugcucuc ccucaucaac      960

gacaugccca ucaccaacga ccaaaagaaa cucaugagca acaacguaca aaucgugcgc     1020

caacaguccu acucaauaau gucaaucauc aaagaagaag ugcuagcaua cgucguacaa     1080

cuaccacucu acggcguaau agauaccccc ugcuggaagc uccauaccuc cccacucugu     1140

accaccaaca ccaaagaagg cucaaacauc ugccuaacgc gcacagaccg uggaugguac     1200

ugugacaacg ccggcuccgu cuccuucuuc ccucaagccg aaacaugcaa aguccaaucc     1260

aacagagucu ucugcgauac caugaacucc cugacacucc caagcgaagu caaccuuugc     1320

aacgucgaua ucuuuaaccc caaauacgac ugcaagauca ugacaucaaa aaccgacgua     1380

uccuccucug uaauaaccuc ccuaggcgca aucguaucau gcuacggcaa aaccaaaugu     1440

accgccucca acaaaaaucg cggcaucauc aaaaccuucu cgaacggcug cgacuacguc     1500

uccaacaaag gcguagacac aguuuccgua ggcaacaccc ucuacuacgu caauaaacag     1560

gaaggcaagu cccucuacgu caaaggcgaa cccaucauca auuucuacga cccccucguu     1620

uuccccuccg augaguucga cgcaagcauc agccagguca acgaaaagau aaaccagucc     1680

cucgccuuca uccgcaaauc agaugaacuc cuucacaacg uuaacgcagg caagagcacc     1740

accaacauca ugaucacaac uauaaucauc gucauaaucg ucauccuacu cucacuaauc     1800

gccgucgguc uccuacuaua uuguaaagcc cgaucaacac cggucacacu cuccaaagac     1860

caacucuccg gaaucaacaa uaucgcuuuc ucgaacuaag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  438
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  438
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agaagcacac cagucacacu aagcaaagau     1860

caacugagug guauaaauaa uauugcauuu aguaacuaag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  439
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  439
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  440
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  440
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcagcacgc ccgugacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc uccaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  441
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  441
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  442
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  442
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggucaacac ccguuacguu gagcaaggac     1860

cagcucucug ggauaaacaa uaucgcuuuc uccaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  443
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  443
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  444
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  444
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cgguccaccc ccguuacgcu gagcaaggac     1860

cagcuuucug gaauuaacaa uaucgcuuuc agcaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  445
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  445
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauau uaaaagcuaa cgcaaucacu acuaucuuaa ccgcaguaac auucuguuuu      240

gcauccggcc aaaacauaac agaagaauuu uaccaaucaa cuugcucugc agucucaaaa      300

gguuaucuau cugcauuaag aacaggcugg uacaccucag uaauaacgau cgaacuauca      360

aacaucaaag aaaacaaaug uaauggaaca gacgcaaaag uaaaacuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguaaccgaa cuccaacucc ucaugcaaag uacaccagca      480

acaaauaaca gagcaagacg ugaacuacca cguuuuauga auuacacgcu caauaacgca      540

aaaaaaacaa auguuacccu aucaaaaaaa cgaaaaagaa gauuccucgg auuccuacua      600

ggcguaggcu cagcaauagc uucaggagua gcaguaucaa aaguacucca ccucgaagga      660

gaaguaaaca aaaucaaaag cgcucuccuc ucaacaaaca aagcaguugu uucacucuca      720

aacggaguau caguacuaac cucaaaagua cuugaccuaa aaaauuauau agacaaacaa      780

cuauuaccaa uaguaaacaa acaaagcugc uccaucucca acaucgagac agucauagaa      840

uuucaacaaa aaaauaaccg ccuauuagaa auaaccagag aauuuucagu aaacgcagga      900

guaacuaccc caguaucaac auauauguua acaaacucag aacuccuaag ucuaaucaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugagca acaauguaca aauaguucgu     1020

caacaaucuu acuccauaau gucuauaaua aaagaagaag uacucgccua uguaguccaa     1080

cuaccacuau acggagucau cgauacacca ugcuggaaac uccacacauc cccacucugu     1140

acuacuaaca ccaaagaagg uucaaauaua ugccuaacca gaacagauag agguugguac     1200

ugcgauaaug caggaucagu auccuuuuuc ccccaagccg aaacaugcaa aguucaaucc     1260

aauagaguau uuugugauac aaugaacucu uuaacccucc cauccgaagu caaucuaugu     1320

aacgucgaca uauuuaaccc aaaauacgau ugcaaaauaa ugacaucaaa aacagacguc     1380

ucauccucag uuauaacguc cuuaggcgcu auaguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa acaaaaacag aggaaucaua aaaacuuucu cuaacgguug cgacuaugua     1500

uccaacaaag gugucgacac aguauccgua ggcaacaccc uuuacuaugu uaauaaacaa     1560

gaaggaaaau cucuauaugu aaaaggcgaa ccaauuauaa auuuuuacga cccccuuguc     1620

uuucccucug acgaauuuga cgcuuccaua ucacaaguca acgaaaaaau caaccaaucc     1680

cucgcauuca uacgcaaauc agacgaacua cuacauaacg ucaacgcagg caaauccaca     1740

acaaacauaa ugauaaccac aaucauaauu guaauaauag uaauacuacu uucucuaaua     1800

gcagucggau uacucuuaua cuguaaagcu cgaucaacac cagucacccu cucuaaagau     1860

caacuauccg gaaucaacaa cauagcuuuc ucaaacuaag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  446
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  446
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucauac ucaaagccaa cgcaaucaca accauacuca ccgccgucac cuucugcuuu      240

gcaucuggcc agaacaucac ugaagaguuc uaccaaucca caugcuccgc cguaagcaaa      300

ggcuaccuau ccgcccuacg caccggcugg uacaccagcg uaaucaccau agaacucucc      360

aauauaaaag aaaacaaaug caacggcacc gacgcaaaag ucaagcuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cguuaccgaa cuccagcuac ucaugcaauc gaccccagca      480

accaacaacc gugcgagacg cgaacucccc cgcuucauga acuacacccu aaacaacgcc      540

aaaaagacca acguaacucu auccaagaaa cgcaaacgcc gcuuccucgg auuccuccuc      600

ggcgucggcu ccgcaaucgc cagcggcguc gccguuagca aaguccuuca ccucgaagga      660

gaaguaaaca aaauuaaaag cgcccucuua uccacaaaca aggccguagu aucccuguca      720

aacggcgucu ccguccuuac auccaaaguc cucgaccuca agaacuacau agacaaacag      780

cuacuaccca uuguaaauaa acaaagcugc ucaauuagca acaucgaaac cguaaucgag      840

uuccagcaga aaaacaacag acuucucgaa aucacccgcg aguucagcgu caacgccggc      900

guaaccaccc cugucucaac auacaugcua accaacagcg aacugcucuc ccucaucaac      960

gacaugccca ucaccaacga ccaaaagaaa cucaugagca acaacguaca aaucgugcgc     1020

caacaguccu acucaauaau gucaaucauc aaagaagaag ugcuagcaua cgucguacaa     1080

cuaccacucu acggcguaau agauaccccc ugcuggaagc uccauaccuc cccacucugu     1140

accaccaaca ccaaagaagg cucaaacauc ugccuaacgc gcacagaccg uggaugguac     1200

ugugacaacg ccggcuccgu cuccuucuuc ccucaagccg aaacaugcaa aguccaaucc     1260

aacagagucu ucugcgauac caugaacucc cugacacucc caagcgaagu caaccuuugc     1320

aacgucgaua ucuuuaaccc caaauacgac ugcaagauca ugacaucaaa aaccgacgua     1380

uccuccucug uaauaaccuc ccuaggcgca aucguaucau gcuacggcaa aaccaaaugu     1440

accgccucca acaaaaaucg cggcaucauc aaaaccuucu cgaacggcug cgacuacguc     1500

uccaacaaag gcguagacac aguuuccgua ggcaacaccc ucuacuacgu caauaaacag     1560

gaaggcaagu cccucuacgu caaaggcgaa cccaucauca auuucuacga cccccucguu     1620

uuccccuccg augaguucga cgcaagcauc agccagguca acgaaaagau aaaccagucc     1680

cucgccuuca uccgcaaauc agaugaacuc cuucacaacg uuaacgcagg caagagcacc     1740

accaacauca ugaucacaac uauaaucauc gucauaaucg ucauccuacu cucacuaauc     1800

gccgucgguc uccuacuaua uuguaaagcc cgaucaacac cggucacacu cuccaaagac     1860

caacucuccg gaaucaacaa uaucgcuuuc ucgaacuaag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  447
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  447
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agaagcacac cagucacacu aagcaaagau     1860

caacugagug guauaaauaa uauugcauuu aguaacuaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  448
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  448
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  449
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  449
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcagcacgc ccgugacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc uccaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  450
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  450
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  451
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  451
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggucaacac ccguuacguu gagcaaggac     1860

cagcucucug ggauaaacaa uaucgcuuuc uccaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  452
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  452
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  453
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  453
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cgguccaccc ccguuacgcu gagcaaggac     1860

cagcuuucug gaauuaacaa uaucgcuuuc agcaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  454
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  454
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauau uaaaagcuaa cgcaaucacu acuaucuuaa ccgcaguaac auucuguuuu      240

gcauccggcc aaaacauaac agaagaauuu uaccaaucaa cuugcucugc agucucaaaa      300

gguuaucuau cugcauuaag aacaggcugg uacaccucag uaauaacgau cgaacuauca      360

aacaucaaag aaaacaaaug uaauggaaca gacgcaaaag uaaaacuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguaaccgaa cuccaacucc ucaugcaaag uacaccagca      480

acaaauaaca gagcaagacg ugaacuacca cguuuuauga auuacacgcu caauaacgca      540

aaaaaaacaa auguuacccu aucaaaaaaa cgaaaaagaa gauuccucgg auuccuacua      600

ggcguaggcu cagcaauagc uucaggagua gcaguaucaa aaguacucca ccucgaagga      660

gaaguaaaca aaaucaaaag cgcucuccuc ucaacaaaca aagcaguugu uucacucuca      720

aacggaguau caguacuaac cucaaaagua cuugaccuaa aaaauuauau agacaaacaa      780

cuauuaccaa uaguaaacaa acaaagcugc uccaucucca acaucgagac agucauagaa      840

uuucaacaaa aaaauaaccg ccuauuagaa auaaccagag aauuuucagu aaacgcagga      900

guaacuaccc caguaucaac auauauguua acaaacucag aacuccuaag ucuaaucaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugagca acaauguaca aauaguucgu     1020

caacaaucuu acuccauaau gucuauaaua aaagaagaag uacucgccua uguaguccaa     1080

cuaccacuau acggagucau cgauacacca ugcuggaaac uccacacauc cccacucugu     1140

acuacuaaca ccaaagaagg uucaaauaua ugccuaacca gaacagauag agguugguac     1200

ugcgauaaug caggaucagu auccuuuuuc ccccaagccg aaacaugcaa aguucaaucc     1260

aauagaguau uuugugauac aaugaacucu uuaacccucc cauccgaagu caaucuaugu     1320

aacgucgaca uauuuaaccc aaaauacgau ugcaaaauaa ugacaucaaa aacagacguc     1380

ucauccucag uuauaacguc cuuaggcgcu auaguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa acaaaaacag aggaaucaua aaaacuuucu cuaacgguug cgacuaugua     1500

uccaacaaag gugucgacac aguauccgua ggcaacaccc uuuacuaugu uaauaaacaa     1560

gaaggaaaau cucuauaugu aaaaggcgaa ccaauuauaa auuuuuacga cccccuuguc     1620

uuucccucug acgaauuuga cgcuuccaua ucacaaguca acgaaaaaau caaccaaucc     1680

cucgcauuca uacgcaaauc agacgaacua cuacauaacg ucaacgcagg caaauccaca     1740

acaaacauaa ugauaaccac aaucauaauu guaauaauag uaauacuacu uucucuaaua     1800

gcagucggau uacucuuaua cuguaaagcu cgaucaacac cagucacccu cucuaaagau     1860

caacuauccg gaaucaacaa cauagcuuuc ucaaacuaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  455
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  455
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucauac ucaaagccaa cgcaaucaca accauacuca ccgccgucac cuucugcuuu      240

gcaucuggcc agaacaucac ugaagaguuc uaccaaucca caugcuccgc cguaagcaaa      300

ggcuaccuau ccgcccuacg caccggcugg uacaccagcg uaaucaccau agaacucucc      360

aauauaaaag aaaacaaaug caacggcacc gacgcaaaag ucaagcuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cguuaccgaa cuccagcuac ucaugcaauc gaccccagca      480

accaacaacc gugcgagacg cgaacucccc cgcuucauga acuacacccu aaacaacgcc      540

aaaaagacca acguaacucu auccaagaaa cgcaaacgcc gcuuccucgg auuccuccuc      600

ggcgucggcu ccgcaaucgc cagcggcguc gccguuagca aaguccuuca ccucgaagga      660

gaaguaaaca aaauuaaaag cgcccucuua uccacaaaca aggccguagu aucccuguca      720

aacggcgucu ccguccuuac auccaaaguc cucgaccuca agaacuacau agacaaacag      780

cuacuaccca uuguaaauaa acaaagcugc ucaauuagca acaucgaaac cguaaucgag      840

uuccagcaga aaaacaacag acuucucgaa aucacccgcg aguucagcgu caacgccggc      900

guaaccaccc cugucucaac auacaugcua accaacagcg aacugcucuc ccucaucaac      960

gacaugccca ucaccaacga ccaaaagaaa cucaugagca acaacguaca aaucgugcgc     1020

caacaguccu acucaauaau gucaaucauc aaagaagaag ugcuagcaua cgucguacaa     1080

cuaccacucu acggcguaau agauaccccc ugcuggaagc uccauaccuc cccacucugu     1140

accaccaaca ccaaagaagg cucaaacauc ugccuaacgc gcacagaccg uggaugguac     1200

ugugacaacg ccggcuccgu cuccuucuuc ccucaagccg aaacaugcaa aguccaaucc     1260

aacagagucu ucugcgauac caugaacucc cugacacucc caagcgaagu caaccuuugc     1320

aacgucgaua ucuuuaaccc caaauacgac ugcaagauca ugacaucaaa aaccgacgua     1380

uccuccucug uaauaaccuc ccuaggcgca aucguaucau gcuacggcaa aaccaaaugu     1440

accgccucca acaaaaaucg cggcaucauc aaaaccuucu cgaacggcug cgacuacguc     1500

uccaacaaag gcguagacac aguuuccgua ggcaacaccc ucuacuacgu caauaaacag     1560

gaaggcaagu cccucuacgu caaaggcgaa cccaucauca auuucuacga cccccucguu     1620

uuccccuccg augaguucga cgcaagcauc agccagguca acgaaaagau aaaccagucc     1680

cucgccuuca uccgcaaauc agaugaacuc cuucacaacg uuaacgcagg caagagcacc     1740

accaacauca ugaucacaac uauaaucauc gucauaaucg ucauccuacu cucacuaauc     1800

gccgucgguc uccuacuaua uuguaaagcc cgaucaacac cggucacacu cuccaaagac     1860

caacucuccg gaaucaacaa uaucgcuuuc ucgaacuaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  456
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  456
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      120

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      180

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      240

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      300

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      360

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      420

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      480

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      540

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      600

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      660

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      720

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      780

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc      840

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu      900

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua      960

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1020

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1080

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1140

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1200

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1260

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1320

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1380

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1440

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1500

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1560

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1620

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1680

auugcuguug gacugcucuu auacuguaag gccagaagca caccagucac acuaagcaaa     1740

gaucaacuga gugguauaaa uaauauugca uuuaguaacu aaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  457
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  457
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  458
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  458
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1140

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1560

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcgcgcagca cgcccgugac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucuccaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  459
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  459
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  460
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  460
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      600

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      720

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      780

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug      900

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu      960

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1020

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1080

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1140

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1200

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1260

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1320

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1380

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1440

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1500

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1560

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1620

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1680

aucgcugugg gccugcuucu guacugcaag gccaggucaa cacccguuac guugagcaag     1740

gaccagcucu cugggauaaa caauaucgcu uucuccaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  461
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  461
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  462
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  462
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      600

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      720

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      780

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu      900

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug      960

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1020

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1080

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1140

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1200

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1260

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1320

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1380

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1440

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1500

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1560

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1680

aucgcggugg ggcugcugcu cuacugcaag gcccggucca cccccguuac gcugagcaag     1740

gaccagcuuu cuggaauuaa caauaucgcu uucagcaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  463
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  463
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuucuaa uauuaaaagc uaacgcaauc acuacuaucu uaaccgcagu aacauucugu      120

uuugcauccg gccaaaacau aacagaagaa uuuuaccaau caacuugcuc ugcagucuca      180

aaagguuauc uaucugcauu aagaacaggc ugguacaccu caguaauaac gaucgaacua      240

ucaaacauca aagaaaacaa auguaaugga acagacgcaa aaguaaaacu aaucaaacaa      300

gaacuagaca aauacaaaaa cgcaguaacc gaacuccaac uccucaugca aaguacacca      360

gcaacaaaua acagagcaag acgugaacua ccacguuuua ugaauuacac gcucaauaac      420

gcaaaaaaaa caaauguuac ccuaucaaaa aaacgaaaaa gaagauuccu cggauuccua      480

cuaggcguag gcucagcaau agcuucagga guagcaguau caaaaguacu ccaccucgaa      540

ggagaaguaa acaaaaucaa aagcgcucuc cucucaacaa acaaagcagu uguuucacuc      600

ucaaacggag uaucaguacu aaccucaaaa guacuugacc uaaaaaauua uauagacaaa      660

caacuauuac caauaguaaa caaacaaagc ugcuccaucu ccaacaucga gacagucaua      720

gaauuucaac aaaaaaauaa ccgccuauua gaaauaacca gagaauuuuc aguaaacgca      780

ggaguaacua ccccaguauc aacauauaug uuaacaaacu cagaacuccu aagucuaauc      840

aacgacaugc caauaaccaa cgaccaaaaa aaacuaauga gcaacaaugu acaaauaguu      900

cgucaacaau cuuacuccau aaugucuaua auaaaagaag aaguacucgc cuauguaguc      960

caacuaccac uauacggagu caucgauaca ccaugcugga aacuccacac auccccacuc     1020

uguacuacua acaccaaaga agguucaaau auaugccuaa ccagaacaga uagagguugg     1080

uacugcgaua augcaggauc aguauccuuu uucccccaag ccgaaacaug caaaguucaa     1140

uccaauagag uauuuuguga uacaaugaac ucuuuaaccc ucccauccga agucaaucua     1200

uguaacgucg acauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaacagac     1260

gucucauccu caguuauaac guccuuaggc gcuauaguau caugcuacgg caaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaauc auaaaaacuu ucucuaacgg uugcgacuau     1380

guauccaaca aaggugucga cacaguaucc guaggcaaca cccuuuacua uguuaauaaa     1440

caagaaggaa aaucucuaua uguaaaaggc gaaccaauua uaaauuuuua cgacccccuu     1500

gucuuucccu cugacgaauu ugacgcuucc auaucacaag ucaacgaaaa aaucaaccaa     1560

ucccucgcau ucauacgcaa aucagacgaa cuacuacaua acgucaacgc aggcaaaucc     1620

acaacaaaca uaaugauaac cacaaucaua auuguaauaa uaguaauacu acuuucucua     1680

auagcagucg gauuacucuu auacuguaaa gcucgaucaa caccagucac ccucucuaaa     1740

gaucaacuau ccggaaucaa caacauagcu uucucaaacu aaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  464
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  464
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uacucaaagc caacgcaauc acaaccauac ucaccgccgu caccuucugc      120

uuugcaucug gccagaacau cacugaagag uucuaccaau ccacaugcuc cgccguaagc      180

aaaggcuacc uauccgcccu acgcaccggc ugguacacca gcguaaucac cauagaacuc      240

uccaauauaa aagaaaacaa augcaacggc accgacgcaa aagucaagcu aauaaaacaa      300

gaacucgaca aauacaaaaa cgccguuacc gaacuccagc uacucaugca aucgacccca      360

gcaaccaaca accgugcgag acgcgaacuc ccccgcuuca ugaacuacac ccuaaacaac      420

gccaaaaaga ccaacguaac ucuauccaag aaacgcaaac gccgcuuccu cggauuccuc      480

cucggcgucg gcuccgcaau cgccagcggc gucgccguua gcaaaguccu ucaccucgaa      540

ggagaaguaa acaaaauuaa aagcgcccuc uuauccacaa acaaggccgu aguaucccug      600

ucaaacggcg ucuccguccu uacauccaaa guccucgacc ucaagaacua cauagacaaa      660

cagcuacuac ccauuguaaa uaaacaaagc ugcucaauua gcaacaucga aaccguaauc      720

gaguuccagc agaaaaacaa cagacuucuc gaaaucaccc gcgaguucag cgucaacgcc      780

ggcguaacca ccccugucuc aacauacaug cuaaccaaca gcgaacugcu cucccucauc      840

aacgacaugc ccaucaccaa cgaccaaaag aaacucauga gcaacaacgu acaaaucgug      900

cgccaacagu ccuacucaau aaugucaauc aucaaagaag aagugcuagc auacgucgua      960

caacuaccac ucuacggcgu aauagauacc cccugcugga agcuccauac cuccccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuaa cgcgcacaga ccguggaugg     1080

uacugugaca acgccggcuc cgucuccuuc uucccucaag ccgaaacaug caaaguccaa     1140

uccaacagag ucuucugcga uaccaugaac ucccugacac ucccaagcga agucaaccuu     1200

ugcaacgucg auaucuuuaa ccccaaauac gacugcaaga ucaugacauc aaaaaccgac     1260

guauccuccu cuguaauaac cucccuaggc gcaaucguau caugcuacgg caaaaccaaa     1320

uguaccgccu ccaacaaaaa ucgcggcauc aucaaaaccu ucucgaacgg cugcgacuac     1380

gucuccaaca aaggcguaga cacaguuucc guaggcaaca cccucuacua cgucaauaaa     1440

caggaaggca agucccucua cgucaaaggc gaacccauca ucaauuucua cgacccccuc     1500

guuuuccccu ccgaugaguu cgacgcaagc aucagccagg ucaacgaaaa gauaaaccag     1560

ucccucgccu ucauccgcaa aucagaugaa cuccuucaca acguuaacgc aggcaagagc     1620

accaccaaca ucaugaucac aacuauaauc aucgucauaa ucgucauccu acucucacua     1680

aucgccgucg gucuccuacu auauuguaaa gcccgaucaa caccggucac acucuccaaa     1740

gaccaacucu ccggaaucaa caauaucgcu uucucgaacu aaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  465
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  465
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagu       60

ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca uuuuguuuug      120

cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca guuagcaaag      180

gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua gaauuaagua      240

auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua aaacaagaau      300

uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc acaccagcaa      360

caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc aacaaugcca      420

aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu uuuuuguuag      480

guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac cuagaagggg      540

aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc agcuuaucaa      600

auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua gauaaacaau      660

uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu gugauagagu      720

uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu aaugcaggug      780

uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca uuaaucaaug      840

auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa auaguuagac      900

agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau guaguacaau      960

uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc ccucuaugua     1020

caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga ggaugguacu     1080

gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa guucaaucaa     1140

aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua aaucucugca     1200

auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa acagauguaa     1260

gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa acuaaaugua     1320

cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc gauuauguau     1380

caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua aauaagcaag     1440

aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac ccauuaguau     1500

uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu aaccagagcc     1560

uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu aaauccacca     1620

caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua ucauuaauug     1680

cuguuggacu gcucuuauac uguaaggcca gaagcacacc agucacacua agcaaagauc     1740

aacugagugg uauaaauaau auugcauuua guaacuaagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  466
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1) R3737/R3938

<400>  466
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc uuccuccugg      480

gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug agccucucca      600

acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg gugaucgagu      720

uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug aacgccgggg      780

ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc cugaucaacg      840

acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag aucguccggc      900

agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac gugguccagc      960

ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc ccccugugca     1020

ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg ggcugguacu     1080

gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag gugcagagca     1140

accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacguga     1260

gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag acgaagugca     1320

ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac ccgcuggucu     1500

uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc aagagcacga     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug ucccucaucg     1680

ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug uccaaggacc     1740

agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  467
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  467
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc uuccuccugg      480

gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug agccucucca      600

acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg gugaucgagu      720

uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug aacgcggggg      780

ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc cugaucaacg      840

acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag aucguccgcc      900

agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac gugguccagc      960

ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc ccccugugca     1020

ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc ggcugguacu     1080

gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag gugcagagca     1140

accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc aaccucugca     1200

acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacguga     1260

gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag acgaagugca     1320

ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc aacaagcagg     1440

agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac ccccuggugu     1500

ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc aaccagagcc     1560

uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc aagagcacga     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug ucccucaucg     1680

ccguggggcu gcugcucuac ugcaaggcgc gcagcacgcc cgugacccug uccaaggacc     1740

agcugagcgg caucaacaac aucgccuucu ccaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  468
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  468
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc aacaacgcca      420

agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc uuccuccucg      480

gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac cucgagggcg      540

aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc ucccucucca      600

acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc gacaagcagc      660

uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc gucaucgagu      720

uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc aacgccggcg      780

ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc cucaucaacg      840

acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag aucguccgcc      900

agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac gucguccagc      960

ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc ccccucugca     1020

ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc ggcugguacu     1080

gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag guccagucca     1140

accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacgucu     1260

ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag accaagugca     1320

ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc gacuacgucu     1380

ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc aacaagcagg     1440

agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac ccccucgucu     1500

uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc aaccaguccc     1560

ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc aaguccacca     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc ucccucaucg     1680

ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc uccaaggacc     1740

agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  469
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  469
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc aauaacgcaa      420

agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc uuucucuuag      480

gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac cuugaaggug      540

aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua agccuaucca      600

acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu gauaagcaac      660

uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc gugauagagu      720

uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc aaugccggag      780

uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu cuuaucaaug      840

acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag aucgugagac      900

agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac gugguucaac      960

uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc ccacugugua     1020

ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg gggugguauu     1080

gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa gugcagucca     1140

accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu aaccucugca     1200

auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa acagacguca     1260

guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag acuaaaugca     1320

cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu gauuacgugu     1380

ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc aauaagcaag     1440

aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac ccccuaguuu     1500

ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc aaccagaguc     1560

ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc aaaagcacca     1620

caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug ucccucaucg     1680

cugugggccu gcuucuguac ugcaaggcca ggucaacacc cguuacguug agcaaggacc     1740

agcucucugg gauaaacaau aucgcuuucu ccaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  470
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  470
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug aacaacgcca      420

agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc uuccugcugg      480

gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac cuggagggcg      540

aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug agccugagca      600

acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc gacaagcagc      660

ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc gugaucgagu      720

uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug aacgccggcg      780

ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc cugaucaacg      840

acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag aucgugagac      900

agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac guggugcagc      960

ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc ccccugugca     1020

ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga ggcugguacu     1080

gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag gugcagagca     1140

acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug aaccugugca     1200

acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag accgacguga     1260

gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag accaagugca     1320

ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac ccccuggugu     1500

uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc aagagcacca     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug agccugaucg     1680

ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug agcaaggacc     1740

agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  471
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  471
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug aauaacgcca      420

agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg uuucuccugg      480

gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac cuggaaggag      540

aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug agccugucua      600

acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu gauaagcaac      660

ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc guuauugagu      720

uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug aaugccggcg      780

ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc cugaucaaug      840

acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag aucguucggc      900

agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac gucgugcaac      960

uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu ccccugugua     1020

caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga ggcugguauu     1080

gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa guccagagca     1140

accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc aaucugugca     1200

auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa acggacguuu     1260

ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag acaaaaugca     1320

ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu gauuacguga     1380

gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug aauaagcaag     1440

aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac ccccuuguuu     1500

ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu aaccagucuc     1560

uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc aaaagcacca     1620

caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu ucucucaucg     1680

cgguggggcu gcugcucuac ugcaaggccc gguccacccc cguuacgcug agcaaggacc     1740

agcuuucugg aauuaacaau aucgcuuuca gcaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  472
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  472
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uucuaauauu aaaagcuaac gcaaucacua cuaucuuaac cgcaguaaca uucuguuuug      120

cauccggcca aaacauaaca gaagaauuuu accaaucaac uugcucugca gucucaaaag      180

guuaucuauc ugcauuaaga acaggcuggu acaccucagu aauaacgauc gaacuaucaa      240

acaucaaaga aaacaaaugu aauggaacag acgcaaaagu aaaacuaauc aaacaagaac      300

uagacaaaua caaaaacgca guaaccgaac uccaacuccu caugcaaagu acaccagcaa      360

caaauaacag agcaagacgu gaacuaccac guuuuaugaa uuacacgcuc aauaacgcaa      420

aaaaaacaaa uguuacccua ucaaaaaaac gaaaaagaag auuccucgga uuccuacuag      480

gcguaggcuc agcaauagcu ucaggaguag caguaucaaa aguacuccac cucgaaggag      540

aaguaaacaa aaucaaaagc gcucuccucu caacaaacaa agcaguuguu ucacucucaa      600

acggaguauc aguacuaacc ucaaaaguac uugaccuaaa aaauuauaua gacaaacaac      660

uauuaccaau aguaaacaaa caaagcugcu ccaucuccaa caucgagaca gucauagaau      720

uucaacaaaa aaauaaccgc cuauuagaaa uaaccagaga auuuucagua aacgcaggag      780

uaacuacccc aguaucaaca uauauguuaa caaacucaga acuccuaagu cuaaucaacg      840

acaugccaau aaccaacgac caaaaaaaac uaaugagcaa caauguacaa auaguucguc      900

aacaaucuua cuccauaaug ucuauaauaa aagaagaagu acucgccuau guaguccaac      960

uaccacuaua cggagucauc gauacaccau gcuggaaacu ccacacaucc ccacucugua     1020

cuacuaacac caaagaaggu ucaaauauau gccuaaccag aacagauaga gguugguacu     1080

gcgauaaugc aggaucagua uccuuuuucc cccaagccga aacaugcaaa guucaaucca     1140

auagaguauu uugugauaca augaacucuu uaacccuccc auccgaaguc aaucuaugua     1200

acgucgacau auuuaaccca aaauacgauu gcaaaauaau gacaucaaaa acagacgucu     1260

cauccucagu uauaacgucc uuaggcgcua uaguaucaug cuacggcaaa acaaaaugua     1320

cagcaucaaa caaaaacaga ggaaucauaa aaacuuucuc uaacgguugc gacuauguau     1380

ccaacaaagg ugucgacaca guauccguag gcaacacccu uuacuauguu aauaaacaag     1440

aaggaaaauc ucuauaugua aaaggcgaac caauuauaaa uuuuuacgac ccccuugucu     1500

uucccucuga cgaauuugac gcuuccauau cacaagucaa cgaaaaaauc aaccaauccc     1560

ucgcauucau acgcaaauca gacgaacuac uacauaacgu caacgcaggc aaauccacaa     1620

caaacauaau gauaaccaca aucauaauug uaauaauagu aauacuacuu ucucuaauag     1680

cagucggauu acucuuauac uguaaagcuc gaucaacacc agucacccuc ucuaaagauc     1740

aacuauccgg aaucaacaac auagcuuucu caaacuaagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  473
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  473
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauacu caaagccaac gcaaucacaa ccauacucac cgccgucacc uucugcuuug      120

caucuggcca gaacaucacu gaagaguucu accaauccac augcuccgcc guaagcaaag      180

gcuaccuauc cgcccuacgc accggcuggu acaccagcgu aaucaccaua gaacucucca      240

auauaaaaga aaacaaaugc aacggcaccg acgcaaaagu caagcuaaua aaacaagaac      300

ucgacaaaua caaaaacgcc guuaccgaac uccagcuacu caugcaaucg accccagcaa      360

ccaacaaccg ugcgagacgc gaacuccccc gcuucaugaa cuacacccua aacaacgcca      420

aaaagaccaa cguaacucua uccaagaaac gcaaacgccg cuuccucgga uuccuccucg      480

gcgucggcuc cgcaaucgcc agcggcgucg ccguuagcaa aguccuucac cucgaaggag      540

aaguaaacaa aauuaaaagc gcccucuuau ccacaaacaa ggccguagua ucccugucaa      600

acggcgucuc cguccuuaca uccaaagucc ucgaccucaa gaacuacaua gacaaacagc      660

uacuacccau uguaaauaaa caaagcugcu caauuagcaa caucgaaacc guaaucgagu      720

uccagcagaa aaacaacaga cuucucgaaa ucacccgcga guucagcguc aacgccggcg      780

uaaccacccc ugucucaaca uacaugcuaa ccaacagcga acugcucucc cucaucaacg      840

acaugcccau caccaacgac caaaagaaac ucaugagcaa caacguacaa aucgugcgcc      900

aacaguccua cucaauaaug ucaaucauca aagaagaagu gcuagcauac gucguacaac      960

uaccacucua cggcguaaua gauacccccu gcuggaagcu ccauaccucc ccacucugua     1020

ccaccaacac caaagaaggc ucaaacaucu gccuaacgcg cacagaccgu ggaugguacu     1080

gugacaacgc cggcuccguc uccuucuucc cucaagccga aacaugcaaa guccaaucca     1140

acagagucuu cugcgauacc augaacuccc ugacacuccc aagcgaaguc aaccuuugca     1200

acgucgauau cuuuaacccc aaauacgacu gcaagaucau gacaucaaaa accgacguau     1260

ccuccucugu aauaaccucc cuaggcgcaa ucguaucaug cuacggcaaa accaaaugua     1320

ccgccuccaa caaaaaucgc ggcaucauca aaaccuucuc gaacggcugc gacuacgucu     1380

ccaacaaagg cguagacaca guuuccguag gcaacacccu cuacuacguc aauaaacagg     1440

aaggcaaguc ccucuacguc aaaggcgaac ccaucaucaa uuucuacgac ccccucguuu     1500

uccccuccga ugaguucgac gcaagcauca gccaggucaa cgaaaagaua aaccaguccc     1560

ucgccuucau ccgcaaauca gaugaacucc uucacaacgu uaacgcaggc aagagcacca     1620

ccaacaucau gaucacaacu auaaucaucg ucauaaucgu cauccuacuc ucacuaaucg     1680

ccgucggucu ccuacuauau uguaaagccc gaucaacacc ggucacacuc uccaaagacc     1740

aacucuccgg aaucaacaau aucgcuuucu cgaacuaagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  474
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (artificial)

<400>  474
gggagaaagc uuaccaugga guugcuaauc cucaaagcaa augcaauuac cacaauccuc       60

acugcaguca cauuuuguuu ugcuucuggu caaaacauca cugaagaauu uuaucaauca      120

acaugcagug caguuagcaa aggcuaucuu agugcucuga gaacugguug guauaccagu      180

guuauaacua uagaauuaag uaauaucaag gaaaauaagu guaauggaac agaugcuaag      240

guaaaauuga uaaaacaaga auuagauaaa uauaaaaaug cuguaacaga auugcaguug      300

cucaugcaaa gcacaccagc aacaaacaau cgagccagaa gagaacuacc aagguuuaug      360

aauuauacac ucaacaaugc caaaaaaacc aauguaacau uaagcaagaa aaggaaaaga      420

agauuucuug guuuuuuguu agguguugga ucugcaaucg ccaguggcgu ugcuguaucu      480

aagguccugc accuagaagg ggaagugaac aagaucaaaa gugcucuacu auccacaaac      540

aaggcuguag ucagcuuauc aaauggaguu agugucuuaa ccagcaaagu guuagaccuc      600

aaaaacuaua uagauaaaca auuguuaccu auugugaaca agcaaagcug cagcauauca      660

aauauagaaa cugugauaga guuccaacaa aagaacaaca gacuacuaga gauuaccagg      720

gaauuuagug uuaaugcagg uguaacuaca ccuguaagca cuuacauguu aacuaauagu      780

gaauuauugu cauuaaucaa ugauaugccu auaacaaaug aucagaaaaa guuaaugucc      840

aacaauguuc aaauaguuag acagcaaagu uacucuauca uguccauaau aaaagaggaa      900

gucuuagcau auguaguaca auuaccacua uaugguguua uagauacacc cuguuggaaa      960

cuacacacau ccccucuaug uacaaccaac acaaaagaag gguccaacau cuguuuaaca     1020

agaacugaca gaggauggua cugugacaau gcaggaucag uaucuuucuu cccacaagcu     1080

gaaacaugua aaguucaauc aaaucgagua uuuugugaca caaugaacag uuuaacauua     1140

ccaagugaag uaaaucucug caauguugac auauucaacc ccaaauauga uuguaaaauu     1200

augacuucaa aaacagaugu aagcagcucc guuaucacau cucuaggagc cauuguguca     1260

ugcuauggca aaacuaaaug uacagcaucc aauaaaaauc guggaaucau aaagacauuu     1320

ucuaacgggu gcgauuaugu aucaaauaaa gggguggaca cugugucugu agguaacaca     1380

uuauauuaug uaaauaagca agaagguaaa agucucuaug uaaaagguga accaauaaua     1440

aauuucuaug acccauuagu auuccccucu gaugaauuug augcaucaau aucucaaguc     1500

aacgagaaga uuaaccagag ccuagcauuu auucguaaau ccgaugaauu auuacauaau     1560

guaaaugcug guaaauccac cacaaauauc augauaacua cuauaauuau agugauuaua     1620

guaauauugu uaucauuaau ugcuguugga cugcucuuau acuguaaggc cagaagcaca     1680

ccagucacac uaagcaaaga ucaacugagu gguauaaaua auauugcauu uaguaacuaa     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  475
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1) R6939/R7003

<400>  475
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

accugcagcg ccgucuccaa gggguaccuc agcgcccugc ggacgggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccaacaac cgcgcccggc gcgagcugcc ccgguucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcgcaagcgg      420

cgcuuccugg gcuuccuccu gggggugggc uccgccaucg cgagcggcgu cgccgugucc      480

aaggugcugc accucgaggg ggaggucaac aagaucaaga gcgcccugcu guccaccaac      540

aaggccgugg ugagccucuc caacggcguc agcgugcuga ccuccaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc aucgucaaca agcagagcug cuccaucagc      660

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      720

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      780

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      840

aacaacgugc agaucguccg gcagcagucc uacagcauca uguccaucau caaggaggag      900

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      960

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg     1020

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1080

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1140

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1260

ugcuacggca agacgaagug caccgccagc aacaagaacc gggggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1440

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1560

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1620

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1680

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  476
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt1)

<400>  476
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccaacaac cgggcccgcc gggagcugcc gcgcuucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcggaagcgc      420

cgguuccugg gcuuccuccu gggggugggc uccgcgaucg ccagcggcgu cgccgugucc      480

aaggugcugc accucgaggg ggaggucaac aagaucaaga gcgcccugcu guccaccaac      540

aaggccgugg ugagccucuc caacggcguc agcgugcuga ccuccaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc aucgucaaca agcagagcug cuccaucagc      660

aacaucgaga cggugaucga guuccagcag aagaacaacc gccuccugga gaucacccgg      720

gaguucagcg ugaacgcggg ggucaccacc cccgugucca cguacaugcu gaccaacagc      780

gagcuccugu cccugaucaa cgacaugccc aucaccaacg accagaagaa gcucaugagc      840

aacaacgugc agaucguccg ccagcagucc uacagcauca uguccaucau caaggaggag      900

gugcuggccu acguggucca gcugccgcuc uacggcguga ucgacacccc cugcuggaag      960

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg     1020

cggaccgacc gcggcuggua cugcgacaac gccggcagcg ucuccuucuu cccccaggcc     1080

gagaccugca aggugcagag caaccgggug uucugcgaca ccaugaacuc ccugacgcug     1140

ccgagcgagg ucaaccucug caacguggac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu gagcuccagc gucaucaccu cccugggggc caucgugagc     1260

ugcuacggca agacgaagug caccgcgagc aacaagaacc gcgggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca ccguguccgu ggggaacacc     1380

cuguacuacg ucaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1440

aacuucuacg acccccuggu guucccgucc gacgaguucg acgccagcau cucccagguc     1500

aacgagaaga ucaaccagag ccuggccuuc auccggaagu ccgacgagcu ccugcacaac     1560

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgugaucauc     1620

gucauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc gcgcagcacg     1680

cccgugaccc uguccaagga ccagcugagc ggcaucaaca acaucgccuu cuccaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  477
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt2)

<400>  477
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccaacaac cgcgcccgcc gcgagcuccc ccgcuucaug      360

aacuacaccc ucaacaacgc caagaagacc aacgucaccc ucuccaagaa gcgcaagcgc      420

cgcuuccucg gcuuccuccu cggcgucggc uccgccaucg ccuccggcgu cgccgucucc      480

aagguccucc accucgaggg cgaggucaac aagaucaagu ccgcccuccu cuccaccaac      540

aaggccgucg ucucccucuc caacggcguc uccguccuca ccuccaaggu ccucgaccuc      600

aagaacuaca ucgacaagca gcuccucccc aucgucaaca agcaguccug cuccaucucc      660

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      720

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      780

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      840

aacaacgucc agaucguccg ccagcagucc uacuccauca uguccaucau caaggaggag      900

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      960

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc     1020

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1080

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1140

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1260

ugcuacggca agaccaagug caccgccucc aacaagaacc gcggcaucau caagaccuuc     1320

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1380

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1440

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1500

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1560

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1620

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1680

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  478
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt3)

<400>  478
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccaacaau agggcucggc gcgaguugcc ucgauuuaug      360

aacuacacgc ucaauaacgc aaagaaaacu aaugugaccc ugucgaagaa acguaagaga      420

agguuccugg gcuuucucuu aggggucgga ucagccauag cuagcggcgu ggccguuagu      480

aaggugcugc accuugaagg ugaggucaac aaaaucaagu ccgcguugcu gucuacaaau      540

aaagcagugg uaagccuauc caacgggguu ucagugcuca cuucuaaggu ccuggaccuu      600

aaaaauuaua uugauaagca acuguugcca aucgugaaca aacagagcug uucuauuucc      660

aacaucgaaa ccgugauaga guuccagcag aagaauaacc ggcuccugga gauuacacgc      720

gaauuuucag ucaaugccgg aguuaccacg ccggugagca cuuacauguu aacaaacagu      780

gagcugcucu cucuuaucaa ugacaugccc auuaccaacg aucaaaagaa acugaugucc      840

aauaacguac agaucgugag acagcagagc uauucgauca ugucuauuau aaaggaagag      900

gucuuggcuu acgugguuca acuaccucug uacggcguga ucgacacucc augcuggaaa      960

cuccauacau ccccacugug uaccacgaau accaaggaag gcucaaacau uugccuuaca     1020

aggacugauc ggggguggua uugugacaau gccggaagug ucagcuucuu uccucaggca     1080

gagaccugca aagugcaguc caaccgcgua uucugugaua caaugaauag ucugacuuug     1140

ccaagcgagg uuaaccucug caauguggac aucuuuaacc ccaaguacga uuguaagaua     1200

augaccucaa aaacagacgu caguuccagc gugauuaccu cucugggugc uaucgucuca     1260

ugcuauggca agacuaaaug cacggccagu aacaagaauc gagggaucau uaaaacauuc     1320

agcaacggau gugauuacgu guccaauaag ggcguugaca ccgugucugu agguaacacu     1380

uuauauuacg ucaauaagca agaagggaaa ucgcuguaug ugaagggaga gccuaucauu     1440

aacuuuuacg acccccuagu uuucccgagc gaugaauuug acgcguccau aucacaggug     1500

aaugagaaaa ucaaccagag ucucgccuuc auuagaaagu cugaugaacu gcuucacaau     1560

gucaacgcag gcaaaagcac cacaaauauc augaucacca cuauuauaau cgugauuauc     1620

guaauuuugc ugucccucau cgcugugggc cugcuucugu acugcaaggc caggucaaca     1680

cccguuacgu ugagcaagga ccagcucucu gggauaaaca auaucgcuuu cuccaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  479
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt4)

<400>  479
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccaacaac agagccagaa gagagcugcc cagauucaug      360

aacuacaccc ugaacaacgc caagaagacc aacgugaccc ugagcaagaa gagaaagaga      420

agauuccugg gcuuccugcu gggcgugggc agcgccaucg ccagcggcgu ggccgugagc      480

aaggugcugc accuggaggg cgaggugaac aagaucaaga gcgcccugcu gagcaccaac      540

aaggccgugg ugagccugag caacggcgug agcgugcuga ccagcaaggu gcuggaccug      600

aagaacuaca ucgacaagca gcugcugccc aucgugaaca agcagagcug cagcaucagc      660

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      720

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      780

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      840

aacaacgugc agaucgugag acagcagagc uacagcauca ugagcaucau caaggaggag      900

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      960

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc     1020

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1080

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1140

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1200

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1260

ugcuacggca agaccaagug caccgccagc aacaagaaca gaggcaucau caagaccuuc     1320

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1440

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1560

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1620

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1680

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  480
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt5)

<400>  480
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacaaacaau cgggcucgca gagagcuccc ucgguuuaug      360

aacuacaccc ugaauaacgc caagaaaaca aaugucaccc uuucuaagaa acgcaagaga      420

cgguuccugg gguuucuccu gggagugggc agcgcgauug ccuccggggu ugcugugagc      480

aagguccuuc accuggaagg agaggugaac aaaaucaagu cugcccuccu guccacgaau      540

aaagcuguug ugagccuguc uaacggcguc uccgugcuca caagcaaggu gcuggaccuu      600

aaaaauuaua uugauaagca acugcucccg aucgucaaca aacagucuug uuccauuagc      660

aacaucgaaa ccguuauuga guuccagcag aagaauaacc gccugcuuga gaucacaaga      720

gaauuuuccg ugaaugccgg cgugaccacc cccgucucua cauacaugcu gacgaacagc      780

gagcuccugu cccugaucaa ugacaugccu auuaccaacg aucaaaagaa acucaugagc      840

aauaacgugc agaucguucg gcagcagucu uauuccauua ugagcaucau uaaggaagag      900

gugcuggcgu acgucgugca acuuccccug uacgggguua ucgacacacc uugcuggaaa      960

cuccauaccu cuccccugug uacaaccaau acgaaggaag gaagcaacau cugccuuaca     1020

cgcaccgaua gaggcuggua uugugacaau gccggguccg ugucuuucuu uccucaggcu     1080

gagaccugca aaguccagag caaccgggug uucugugaua caaugaacuc ccugacccuc     1140

ccgagcgagg ucaaucugug caauguggac auuuuuaacc ccaaguacga uuguaagauc     1200

augacaucua aaacggacgu uuccagcucu gugauuaccu cccugggagc caucgucagc     1260

ugcuauggca agacaaaaug caccgcuucc aacaagaauc gcgggauuau caaaacauuc     1320

ucuaacggau gugauuacgu gagcaauaag ggcguugaca ccguguccgu cggcaacacg     1380

cucuauuacg ugaauaagca agaagggaaa ucucuguaug ugaagggaga gccuaucauu     1440

aacuuuuacg acccccuugu uuucccuagc gaugaauuug acgccuccau cagccagguc     1500

aaugagaaaa uuaaccaguc ucuggccuuc aucagaaagu ccgaugaacu ccugcacaau     1560

gugaacgcug gcaaaagcac cacaaauauu augaucacca caauuaucau cgugauuauc     1620

gucauucugc uuucucucau cgcggugggg cugcugcucu acugcaaggc ccgguccacc     1680

cccguuacgc ugagcaagga ccagcuuucu ggaauuaaca auaucgcuuu cagcaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  481
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt6)

<400>  481
gggagaaagc uuaccaugga acuucuaaua uuaaaagcua acgcaaucac uacuaucuua       60

accgcaguaa cauucuguuu ugcauccggc caaaacauaa cagaagaauu uuaccaauca      120

acuugcucug cagucucaaa agguuaucua ucugcauuaa gaacaggcug guacaccuca      180

guaauaacga ucgaacuauc aaacaucaaa gaaaacaaau guaauggaac agacgcaaaa      240

guaaaacuaa ucaaacaaga acuagacaaa uacaaaaacg caguaaccga acuccaacuc      300

cucaugcaaa guacaccagc aacaaauaac agagcaagac gugaacuacc acguuuuaug      360

aauuacacgc ucaauaacgc aaaaaaaaca aauguuaccc uaucaaaaaa acgaaaaaga      420

agauuccucg gauuccuacu aggcguaggc ucagcaauag cuucaggagu agcaguauca      480

aaaguacucc accucgaagg agaaguaaac aaaaucaaaa gcgcucuccu cucaacaaac      540

aaagcaguug uuucacucuc aaacggagua ucaguacuaa ccucaaaagu acuugaccua      600

aaaaauuaua uagacaaaca acuauuacca auaguaaaca aacaaagcug cuccaucucc      660

aacaucgaga cagucauaga auuucaacaa aaaaauaacc gccuauuaga aauaaccaga      720

gaauuuucag uaaacgcagg aguaacuacc ccaguaucaa cauauauguu aacaaacuca      780

gaacuccuaa gucuaaucaa cgacaugcca auaaccaacg accaaaaaaa acuaaugagc      840

aacaauguac aaauaguucg ucaacaaucu uacuccauaa ugucuauaau aaaagaagaa      900

guacucgccu auguagucca acuaccacua uacggaguca ucgauacacc augcuggaaa      960

cuccacacau ccccacucug uacuacuaac accaaagaag guucaaauau augccuaacc     1020

agaacagaua gagguuggua cugcgauaau gcaggaucag uauccuuuuu cccccaagcc     1080

gaaacaugca aaguucaauc caauagagua uuuugugaua caaugaacuc uuuaacccuc     1140

ccauccgaag ucaaucuaug uaacgucgac auauuuaacc caaaauacga uugcaaaaua     1200

augacaucaa aaacagacgu cucauccuca guuauaacgu ccuuaggcgc uauaguauca     1260

ugcuacggca aaacaaaaug uacagcauca aacaaaaaca gaggaaucau aaaaacuuuc     1320

ucuaacgguu gcgacuaugu auccaacaaa ggugucgaca caguauccgu aggcaacacc     1380

cuuuacuaug uuaauaaaca agaaggaaaa ucucuauaug uaaaaggcga accaauuaua     1440

aauuuuuacg acccccuugu cuuucccucu gacgaauuug acgcuuccau aucacaaguc     1500

aacgaaaaaa ucaaccaauc ccucgcauuc auacgcaaau cagacgaacu acuacauaac     1560

gucaacgcag gcaaauccac aacaaacaua augauaacca caaucauaau uguaauaaua     1620

guaauacuac uuucucuaau agcagucgga uuacucuuau acuguaaagc ucgaucaaca     1680

ccagucaccc ucucuaaaga ucaacuaucc ggaaucaaca acauagcuuu cucaaacuaa     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  482
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0 (opt11)

<400>  482
gggagaaagc uuaccaugga acuccucaua cucaaagcca acgcaaucac aaccauacuc       60

accgccguca ccuucugcuu ugcaucuggc cagaacauca cugaagaguu cuaccaaucc      120

acaugcuccg ccguaagcaa aggcuaccua uccgcccuac gcaccggcug guacaccagc      180

guaaucacca uagaacucuc caauauaaaa gaaaacaaau gcaacggcac cgacgcaaaa      240

gucaagcuaa uaaaacaaga acucgacaaa uacaaaaacg ccguuaccga acuccagcua      300

cucaugcaau cgaccccagc aaccaacaac cgugcgagac gcgaacuccc ccgcuucaug      360

aacuacaccc uaaacaacgc caaaaagacc aacguaacuc uauccaagaa acgcaaacgc      420

cgcuuccucg gauuccuccu cggcgucggc uccgcaaucg ccagcggcgu cgccguuagc      480

aaaguccuuc accucgaagg agaaguaaac aaaauuaaaa gcgcccucuu auccacaaac      540

aaggccguag uaucccuguc aaacggcguc uccguccuua cauccaaagu ccucgaccuc      600

aagaacuaca uagacaaaca gcuacuaccc auuguaaaua aacaaagcug cucaauuagc      660

aacaucgaaa ccguaaucga guuccagcag aaaaacaaca gacuucucga aaucacccgc      720

gaguucagcg ucaacgccgg cguaaccacc ccugucucaa cauacaugcu aaccaacagc      780

gaacugcucu cccucaucaa cgacaugccc aucaccaacg accaaaagaa acucaugagc      840

aacaacguac aaaucgugcg ccaacagucc uacucaauaa ugucaaucau caaagaagaa      900

gugcuagcau acgucguaca acuaccacuc uacggcguaa uagauacccc cugcuggaag      960

cuccauaccu ccccacucug uaccaccaac accaaagaag gcucaaacau cugccuaacg     1020

cgcacagacc guggauggua cugugacaac gccggcuccg ucuccuucuu cccucaagcc     1080

gaaacaugca aaguccaauc caacagaguc uucugcgaua ccaugaacuc ccugacacuc     1140

ccaagcgaag ucaaccuuug caacgucgau aucuuuaacc ccaaauacga cugcaagauc     1200

augacaucaa aaaccgacgu auccuccucu guaauaaccu cccuaggcgc aaucguauca     1260

ugcuacggca aaaccaaaug uaccgccucc aacaaaaauc gcggcaucau caaaaccuuc     1320

ucgaacggcu gcgacuacgu cuccaacaaa ggcguagaca caguuuccgu aggcaacacc     1380

cucuacuacg ucaauaaaca ggaaggcaag ucccucuacg ucaaaggcga acccaucauc     1440

aauuucuacg acccccucgu uuuccccucc gaugaguucg acgcaagcau cagccagguc     1500

aacgaaaaga uaaaccaguc ccucgccuuc auccgcaaau cagaugaacu ccuucacaac     1560

guuaacgcag gcaagagcac caccaacauc augaucacaa cuauaaucau cgucauaauc     1620

gucauccuac ucucacuaau cgccgucggu cuccuacuau auuguaaagc ccgaucaaca     1680

ccggucacac ucuccaaaga ccaacucucc ggaaucaaca auaucgcuuu cucgaacuaa     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  483
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del

<400>  483

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  484
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (artificial) from 
       HRSV(A2)__F-del

<400>  484
auggaguugc uaauccucaa agcaaaugca auuaccacaa uccucacugc agucacauuu       60

uguuuugcuu cuggucaaaa caucacugaa gaauuuuauc aaucaacaug cagugcaguu      120

agcaaaggcu aucuuagugc ucugagaacu gguugguaua ccaguguuau aacuauagaa      180

uuaaguaaua ucaaggaaaa uaaguguaau ggaacagaug cuaagguaaa auugauaaaa      240

caagaauuag auaaauauaa aaaugcugua acagaauugc aguugcucau gcaaagcaca      300

ccagcaacaa acaaucgagc cagaagagaa cuaccaaggu uuaugaauua uacacucaac      360

aaugccaaaa aaaccaaugu aacauuaagc aagaaaagga aaagaagauu ucuugguuuu      420

uuguuaggug uuggaucugc aaucgccagu ggcguugcug uaucuaaggu ccugcaccua      480

gaaggggaag ugaacaagau caaaagugcu cuacuaucca caaacaaggc uguagucagc      540

uuaucaaaug gaguuagugu cuuaaccagc aaaguguuag accucaaaaa cuauauagau      600

aaacaauugu uaccuauugu gaacaagcaa agcugcagca uaucaaauau agaaacugug      660

auagaguucc aacaaaagaa caacagacua cuagagauua ccagggaauu uaguguuaau      720

gcagguguaa cuacaccugu aagcacuuac auguuaacua auagugaauu auugucauua      780

aucaaugaua ugccuauaac aaaugaucag aaaaaguuaa uguccaacaa uguucaaaua      840

guuagacagc aaaguuacuc uaucaugucc auaauaaaag aggaagucuu agcauaugua      900

guacaauuac cacuauaugg uguuauagau acacccuguu ggaaacuaca cacauccccu      960

cuauguacaa ccaacacaaa agaagggucc aacaucuguu uaacaagaac ugacagagga     1020

ugguacugug acaaugcagg aucaguaucu uucuucccac aagcugaaac auguaaaguu     1080

caaucaaauc gaguauuuug ugacacaaug aacaguuuaa cauuaccaag ugaaguaaau     1140

cucugcaaug uugacauauu caaccccaaa uaugauugua aaauuaugac uucaaaaaca     1200

gauguaagca gcuccguuau cacaucucua ggagccauug ugucaugcua uggcaaaacu     1260

aaauguacag cauccaauaa aaaucgugga aucauaaaga cauuuucuaa cgggugcgau     1320

uauguaucaa auaaaggggu ggacacugug ucuguaggua acacauuaua uuauguaaau     1380

aagcaagaag guaaaagucu cuauguaaaa ggugaaccaa uaauaaauuu cuaugaccca     1440

uuaguauucc ccucugauga auuugaugca ucaauaucuc aagucaacga gaagauuaac     1500

cagagccuag cauuuauucg uaaauccgau gaauuauuac auaauguaaa ugcugguaaa     1560

uccaccacaa auaucaugau aacuacuaua auuauaguga uuauaguaau auuguuauca     1620

uuaauugcug uuggacugcu cuuauacugu aaggccagau aa                        1662


<210>  485
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from HRSV(A2)__F-del

<400>  485
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccaccug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacg ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaacca acaaccgcgc ccggcgcgag cugccccggu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgca agcggcgcuu ccugggcuuc      420

cuccuggggg ugggcuccgc caucgcgagc ggcgucgccg uguccaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccucc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccaucgu caacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugucc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu ga                        1662


<210>  486
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from HRSV(A2)__F-del

<400>  486
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccacca acaaccgggc ccgccgggag cugccgcgcu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgga agcgccgguu ccugggcuuc      420

cuccuggggg ugggcuccgc gaucgccagc ggcgucgccg uguccaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccucc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccaucgu caacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccgccuc cuggagauca cccgggaguu cagcgugaac      720

gcggggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccgccagc aguccuacag caucaugucc aucaucaagg aggaggugcu ggccuacgug      900

guccagcugc cgcucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcggac cgaccgcggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaacc ggguguucug cgacaccaug aacucccuga cgcugccgag cgaggucaac     1140

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgucau caccucccug ggggccaucg ugagcugcua cggcaagacg     1260

aagugcaccg cgagcaacaa gaaccgcggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacaccgug uccgugggga acacccugua cuacgucaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cguccgacga guucgacgcc agcaucuccc aggucaacga gaagaucaac     1500

cagagccugg ccuucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguga ucaucgucau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcgcgcu ga                        1662


<210>  487
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from HRSV(A2)__F-del

<400>  487
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccacca acaaccgcgc ccgccgcgag cucccccgcu ucaugaacua cacccucaac      360

aacgccaaga agaccaacgu cacccucucc aagaagcgca agcgccgcuu ccucggcuuc      420

cuccucggcg ucggcuccgc caucgccucc ggcgucgccg ucuccaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccucc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccaucgu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugucc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ga                        1662


<210>  488
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from HRSV(A2)__F-del

<400>  488
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccacca acaauagggc ucggcgcgag uugccucgau uuaugaacua cacgcucaau      360

aacgcaaaga aaacuaaugu gacccugucg aagaaacgua agagaagguu ccugggcuuu      420

cucuuagggg ucggaucagc cauagcuagc ggcguggccg uuaguaaggu gcugcaccuu      480

gaaggugagg ucaacaaaau caaguccgcg uugcugucua caaauaaagc agugguaagc      540

cuauccaacg ggguuucagu gcucacuucu aagguccugg accuuaaaaa uuauauugau      600

aagcaacugu ugccaaucgu gaacaaacag agcuguucua uuuccaacau cgaaaccgug      660

auagaguucc agcagaagaa uaaccggcuc cuggagauua cacgcgaauu uucagucaau      720

gccggaguua ccacgccggu gagcacuuac auguuaacaa acagugagcu gcucucucuu      780

aucaaugaca ugcccauuac caacgaucaa aagaaacuga uguccaauaa cguacagauc      840

gugagacagc agagcuauuc gaucaugucu auuauaaagg aagaggucuu ggcuuacgug      900

guucaacuac cucuguacgg cgugaucgac acuccaugcu ggaaacucca uacaucccca      960

cuguguacca cgaauaccaa ggaaggcuca aacauuugcc uuacaaggac ugaucggggg     1020

ugguauugug acaaugccgg aagugucagc uucuuuccuc aggcagagac cugcaaagug     1080

caguccaacc gcguauucug ugauacaaug aauagucuga cuuugccaag cgagguuaac     1140

cucugcaaug uggacaucuu uaaccccaag uacgauugua agauaaugac cucaaaaaca     1200

gacgucaguu ccagcgugau uaccucucug ggugcuaucg ucucaugcua uggcaagacu     1260

aaaugcacgg ccaguaacaa gaaucgaggg aucauuaaaa cauucagcaa cggaugugau     1320

uacgugucca auaagggcgu ugacaccgug ucuguaggua acacuuuaua uuacgucaau     1380

aagcaagaag ggaaaucgcu guaugugaag ggagagccua ucauuaacuu uuacgacccc     1440

cuaguuuucc cgagcgauga auuugacgcg uccauaucac aggugaauga gaaaaucaac     1500

cagagucucg ccuucauuag aaagucugau gaacugcuuc acaaugucaa cgcaggcaaa     1560

agcaccacaa auaucaugau caccacuauu auaaucguga uuaucguaau uuugcugucc     1620

cucaucgcug ugggccugcu ucuguacugc aaggccaggu ga                        1662


<210>  489
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from HRSV(A2)__F-del

<400>  489
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccacca acaacagagc cagaagagag cugcccagau ucaugaacua cacccugaac      360

aacgccaaga agaccaacgu gacccugagc aagaagagaa agagaagauu ccugggcuuc      420

cugcugggcg ugggcagcgc caucgccagc ggcguggccg ugagcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccagc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccaucgu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugagc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau ga                        1662


<210>  490
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from HRSV(A2)__F-del

<400>  490
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacaa acaaucgggc ucgcagagag cucccucggu uuaugaacua cacccugaau      360

aacgccaaga aaacaaaugu cacccuuucu aagaaacgca agagacgguu ccugggguuu      420

cuccugggag ugggcagcgc gauugccucc gggguugcug ugagcaaggu ccuucaccug      480

gaaggagagg ugaacaaaau caagucugcc cuccugucca cgaauaaagc uguugugagc      540

cugucuaacg gcgucuccgu gcucacaagc aaggugcugg accuuaaaaa uuauauugau      600

aagcaacugc ucccgaucgu caacaaacag ucuuguucca uuagcaacau cgaaaccguu      660

auugaguucc agcagaagaa uaaccgccug cuugagauca caagagaauu uuccgugaau      720

gccggcguga ccacccccgu cucuacauac augcugacga acagcgagcu ccugucccug      780

aucaaugaca ugccuauuac caacgaucaa aagaaacuca ugagcaauaa cgugcagauc      840

guucggcagc agucuuauuc cauuaugagc aucauuaagg aagaggugcu ggcguacguc      900

gugcaacuuc cccuguacgg gguuaucgac acaccuugcu ggaaacucca uaccucuccc      960

cuguguacaa ccaauacgaa ggaaggaagc aacaucugcc uuacacgcac cgauagaggc     1020

ugguauugug acaaugccgg guccgugucu uucuuuccuc aggcugagac cugcaaaguc     1080

cagagcaacc ggguguucug ugauacaaug aacucccuga cccucccgag cgaggucaau     1140

cugugcaaug uggacauuuu uaaccccaag uacgauugua agaucaugac aucuaaaacg     1200

gacguuucca gcucugugau uaccucccug ggagccaucg ucagcugcua uggcaagaca     1260

aaaugcaccg cuuccaacaa gaaucgcggg auuaucaaaa cauucucuaa cggaugugau     1320

uacgugagca auaagggcgu ugacaccgug uccgucggca acacgcucua uuacgugaau     1380

aagcaagaag ggaaaucucu guaugugaag ggagagccua ucauuaacuu uuacgacccc     1440

cuuguuuucc cuagcgauga auuugacgcc uccaucagcc aggucaauga gaaaauuaac     1500

cagucucugg ccuucaucag aaaguccgau gaacuccugc acaaugugaa cgcuggcaaa     1560

agcaccacaa auauuaugau caccacaauu aucaucguga uuaucgucau ucugcuuucu     1620

cucaucgcgg uggggcugcu gcucuacugc aaggcccggu ga                        1662


<210>  491
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from HRSV(A2)__F-del

<400>  491
auggaauuac uaauacucaa agccaacgca auaacaacaa uacuaacagc aguaacauuc       60

ugcuucgcau caggacaaaa caucacagaa gaauuuuacc aaaguacaug cagugcaguc      120

ucuaaaggau accucagugc cuuacgcaca ggaugguaca caucaguaau aacaaucgaa      180

cuuucaaaca uaaaagaaaa caaaugcaau ggaaccgacg ccaaaguaaa acuaaucaaa      240

caagaacuag acaaauauaa aaaugcagua acagaauuac aacuccuaau gcaauccaca      300

ccagcaacaa auaacagagc aagacgagaa cucccucgau ucaugaauua cacauuaaac      360

aacgcaaaaa aaacuaacgu aacuuuauca aaaaaaagaa aacguagauu ucuaggauuc      420

cuacuaggcg uaggguccgc cauugcauca ggaguagcag uuagcaaagu auuacauuua      480

gaaggagaag uaaauaaaau caaaagcgca cuacucucaa ccaacaaagc aguaguauca      540

cucucaaacg gaguaucagu acuaacaucc aaaguacucg accucaaaaa cuacauagac      600

aaacaauuac uacccauagu aaacaaacaa ucaugcucua uaucaaauau cgaaacagua      660

aucgaauuuc aacaaaaaaa caaucgacua cuugaaauaa caagagaguu cuccgucaau      720

gccggaguca ccacaccagu cucaacauac augcuaacca acucugaacu ccuaucacua      780

auaaaugaca ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguacaaaua      840

guacgacaac aaaguuauuc cauaaugagu auaaucaaag aagaaguguu agcauacgua      900

guccaacuac cauuauaugg aguaauagac acaccauguu ggaaauuaca caccucacca      960

cucugcacua ccaauacaaa agaaggcuca aauauaugcc uaacucgcac agacagaggc     1020

ugguacugcg auaacgcagg auccguaucu uucuuucccc aagcagaaac uugcaaagua     1080

caaucaaaca gagucuucug cgacaccaug aauagucuca cauuaccauc ugaaguaaac     1140

cuauguaacg uagauauauu caauccaaaa uacgacugca aaauaaugac aucaaaaacc     1200

gacgucucua gcaguguaau cacaucacua ggagcaauag uaagcugcua uggaaaaaca     1260

aaauguacag caucaaacaa aaacagggga auaauaaaaa ccuucucaaa cggaugugac     1320

uacguaucaa auaaaggcgu agacacagua agcguaggaa acacccuaua cuacguuaac     1380

aaacaagaag ggaaaucauu auacguaaaa ggagaaccaa uaauaaacuu cuacgaucca     1440

cucguauucc cauccgacga auuugacgcc agcauauccc aaguuaacga aaaaauaaac     1500

caaucacuug cauuuauacg aaaaucugau gaacuucucc acaacguaaa ugcaggaaaa     1560

uccaccacca auauaaugau cacaacuauc aucauaguaa uaaucgucau uuuacuauca     1620

uuaauagcag uuggccuacu ucuauacugc aaagcaagau aa                        1662


<210>  492
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from HRSV(A2)__F-del

<400>  492
auggaacuac uaauccuaaa agccaacgcg aucaccacca uccuaacggc agucaccuuc       60

ugcuucgcau caggccaaaa caucacagaa gaguucuacc aaagcacaug cuccgccgua      120

uccaaaggcu accucagcgc ccuacgcaca ggcugguaca caucugucau caccauagaa      180

cucuccaaca ucaaagaaaa caaaugcaac ggcacugacg ccaaaguaaa gcugaucaaa      240

caagaacucg acaaauacaa aaacgcaguc accgaacucc aacuacucau gcaauccacc      300

ccugcaacca acaacagggc ccgccgcgaa cucccccgcu ucaugaacua cacuuuaaac      360

aacgccaaaa agaccaacgu cacacucagc aagaaacgga aacgacgauu ccuaggguuu      420

cuccuaggcg ucggcucggc aaucgccucc ggcgucgccg uaagcaaagu acuacaccua      480

gaaggcgaag ugaacaaaau caaaagugcc cuucucucca ccaacaaggc cguagucucu      540

cuauccaacg gagucucagu ccucaccuca aagguccucg accucaaaaa cuacaucgac      600

aaacaacuac uccccauugu caacaagcag ucaugcucca uaucaaacau cgaaaccguc      660

aucgaguucc aacagaaaaa caaccgacuc cucgaaauaa ccagagaguu cucggucaac      720

gccggcguca ccaccccagu cagcaccuac augcucacua acuccgaacu ccuaucccuc      780

aucaacgaca ugccaauuac caacgaccaa aagaaacuaa ugucgaacaa cguucaaauc      840

guccgacaac aaaguuacuc caucaugagc auaaucaaag aagaaguucu agcguacguc      900

guccaacucc cacuauacgg cgucaucgac acuccgugcu ggaaacucca cacaucaccc      960

cuauguacaa ccaacacaaa agaaggcagc aacaucugcc ucacccgcac cgaccgaggg     1020

ugguauugcg auaacgcugg cagcgucucc uucuuccccc aagccgaaac cugcaaaguc     1080

caaucaaaca gaguauucug cgacaccaug aacucccuua cucucccuag cgaagucaac     1140

cucugcaacg uugacauauu caaccccaaa uacgacugca aaaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau cacaucucua ggugccauug ucuccugcua cggaaaaacc     1260

aaaugcacag ccuccaacaa aaaccgcggc aucauaaaaa ccuucuccaa cggcugcgac     1320

uacgucagua auaaaggcgu cgacacggua uccguuggga auacgcuuua cuacguaaau     1380

aaacaagaag gcaaaucccu cuacgucaaa ggugaaccca ucauaaacuu cuacgacccg     1440

cuuguguucc cauccgacga guucgacgcc agcaucagcc aggucaacga aaagaucaac     1500

caaucccuag ccuucauccg caaaagcgac gaacuacuac acaacgucaa cgccggaaaa     1560

uccacaacca acaucaugau caccaccauc aucaucguca ucaucguaau ccuacucucu     1620

cucaucgccg ucggccuccu acuguacugu aaagcccgau ag                        1662


<210>  493
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  493
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagauaag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  494
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  494
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  495
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  495
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  496
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  496
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  497
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  497
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  498
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  498
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  499
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  499
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  500
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  500
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uacucaaagc caacgcaaua acaacaauac      120

uaacagcagu aacauucugc uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa      180

guacaugcag ugcagucucu aaaggauacc ucagugccuu acgcacagga ugguacacau      240

caguaauaac aaucgaacuu ucaaacauaa aagaaaacaa augcaaugga accgacgcca      300

aaguaaaacu aaucaaacaa gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac      360

uccuaaugca auccacacca gcaacaaaua acagagcaag acgagaacuc ccucgauuca      420

ugaauuacac auuaaacaac gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac      480

guagauuucu aggauuccua cuaggcguag gguccgccau ugcaucagga guagcaguua      540

gcaaaguauu acauuuagaa ggagaaguaa auaaaaucaa aagcgcacua cucucaacca      600

acaaagcagu aguaucacuc ucaaacggag uaucaguacu aacauccaaa guacucgacc      660

ucaaaaacua cauagacaaa caauuacuac ccauaguaaa caaacaauca ugcucuauau      720

caaauaucga aacaguaauc gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa      780

gagaguucuc cgucaaugcc ggagucacca caccagucuc aacauacaug cuaaccaacu      840

cugaacuccu aucacuaaua aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu      900

caaauaacgu acaaauagua cgacaacaaa guuauuccau aaugaguaua aucaaagaag      960

aaguguuagc auacguaguc caacuaccau uauauggagu aauagacaca ccauguugga     1020

aauuacacac cucaccacuc ugcacuacca auacaaaaga aggcucaaau auaugccuaa     1080

cucgcacaga cagaggcugg uacugcgaua acgcaggauc cguaucuuuc uuuccccaag     1140

cagaaacuug caaaguacaa ucaaacagag ucuucugcga caccaugaau agucucacau     1200

uaccaucuga aguaaaccua uguaacguag auauauucaa uccaaaauac gacugcaaaa     1260

uaaugacauc aaaaaccgac gucucuagca guguaaucac aucacuagga gcaauaguaa     1320

gcugcuaugg aaaaacaaaa uguacagcau caaacaaaaa caggggaaua auaaaaaccu     1380

ucucaaacgg augugacuac guaucaaaua aaggcguaga cacaguaagc guaggaaaca     1440

cccuauacua cguuaacaaa caagaaggga aaucauuaua cguaaaagga gaaccaauaa     1500

uaaacuucua cgauccacuc guauucccau ccgacgaauu ugacgccagc auaucccaag     1560

uuaacgaaaa aauaaaccaa ucacuugcau uuauacgaaa aucugaugaa cuucuccaca     1620

acguaaaugc aggaaaaucc accaccaaua uaaugaucac aacuaucauc auaguaauaa     1680

ucgucauuuu acuaucauua auagcaguug gccuacuucu auacugcaaa gcaagauaag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  501
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  501
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc caacgcgauc accaccaucc      120

uaacggcagu caccuucugc uucgcaucag gccaaaacau cacagaagag uucuaccaaa      180

gcacaugcuc cgccguaucc aaaggcuacc ucagcgcccu acgcacaggc ugguacacau      240

cugucaucac cauagaacuc uccaacauca aagaaaacaa augcaacggc acugacgcca      300

aaguaaagcu gaucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuccaac      360

uacucaugca auccaccccu gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca      420

ugaacuacac uuuaaacaac gccaaaaaga ccaacgucac acucagcaag aaacggaaac      480

gacgauuccu aggguuucuc cuaggcgucg gcucggcaau cgccuccggc gucgccguaa      540

gcaaaguacu acaccuagaa ggcgaaguga acaaaaucaa aagugcccuu cucuccacca      600

acaaggccgu agucucucua uccaacggag ucucaguccu caccucaaag guccucgacc      660

ucaaaaacua caucgacaaa caacuacucc ccauugucaa caagcaguca ugcuccauau      720

caaacaucga aaccgucauc gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca      780

gagaguucuc ggucaacgcc ggcgucacca ccccagucag caccuacaug cucacuaacu      840

ccgaacuccu aucccucauc aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu      900

cgaacaacgu ucaaaucguc cgacaacaaa guuacuccau caugagcaua aucaaagaag      960

aaguucuagc guacgucguc caacucccac uauacggcgu caucgacacu ccgugcugga     1020

aacuccacac aucaccccua uguacaacca acacaaaaga aggcagcaac aucugccuca     1080

cccgcaccga ccgagggugg uauugcgaua acgcuggcag cgucuccuuc uucccccaag     1140

ccgaaaccug caaaguccaa ucaaacagag uauucugcga caccaugaac ucccuuacuc     1200

ucccuagcga agucaaccuc ugcaacguug acauauucaa ccccaaauac gacugcaaaa     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac aucucuaggu gccauugucu     1320

ccugcuacgg aaaaaccaaa ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu     1380

ucuccaacgg cugcgacuac gucaguaaua aaggcgucga cacgguaucc guugggaaua     1440

cgcuuuacua cguaaauaaa caagaaggca aaucccucua cgucaaaggu gaacccauca     1500

uaaacuucua cgacccgcuu guguucccau ccgacgaguu cgacgccagc aucagccagg     1560

ucaacgaaaa gaucaaccaa ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca     1620

acgucaacgc cggaaaaucc acaaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucguaauccu acucucucuc aucgccgucg gccuccuacu guacuguaaa gcccgauagg     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  502
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  502
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  503
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  503
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  504
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  504
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  505
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  505
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  506
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  506
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  507
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  507
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  508
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  508
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  509
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  509
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau acucaaagcc      120

aacgcaauaa caacaauacu aacagcagua acauucugcu ucgcaucagg acaaaacauc      180

acagaagaau uuuaccaaag uacaugcagu gcagucucua aaggauaccu cagugccuua      240

cgcacaggau gguacacauc aguaauaaca aucgaacuuu caaacauaaa agaaaacaaa      300

ugcaauggaa ccgacgccaa aguaaaacua aucaaacaag aacuagacaa auauaaaaau      360

gcaguaacag aauuacaacu ccuaaugcaa uccacaccag caacaaauaa cagagcaaga      420

cgagaacucc cucgauucau gaauuacaca uuaaacaacg caaaaaaaac uaacguaacu      480

uuaucaaaaa aaagaaaacg uagauuucua ggauuccuac uaggcguagg guccgccauu      540

gcaucaggag uagcaguuag caaaguauua cauuuagaag gagaaguaaa uaaaaucaaa      600

agcgcacuac ucucaaccaa caaagcagua guaucacucu caaacggagu aucaguacua      660

acauccaaag uacucgaccu caaaaacuac auagacaaac aauuacuacc cauaguaaac      720

aaacaaucau gcucuauauc aaauaucgaa acaguaaucg aauuucaaca aaaaaacaau      780

cgacuacuug aaauaacaag agaguucucc gucaaugccg gagucaccac accagucuca      840

acauacaugc uaaccaacuc ugaacuccua ucacuaauaa augacaugcc aauaacaaac      900

gaccaaaaaa aacuaauguc aaauaacgua caaauaguac gacaacaaag uuauuccaua      960

augaguauaa ucaaagaaga aguguuagca uacguagucc aacuaccauu auauggagua     1020

auagacacac cauguuggaa auuacacacc ucaccacucu gcacuaccaa uacaaaagaa     1080

ggcucaaaua uaugccuaac ucgcacagac agaggcuggu acugcgauaa cgcaggaucc     1140

guaucuuucu uuccccaagc agaaacuugc aaaguacaau caaacagagu cuucugcgac     1200

accaugaaua gucucacauu accaucugaa guaaaccuau guaacguaga uauauucaau     1260

ccaaaauacg acugcaaaau aaugacauca aaaaccgacg ucucuagcag uguaaucaca     1320

ucacuaggag caauaguaag cugcuaugga aaaacaaaau guacagcauc aaacaaaaac     1380

aggggaauaa uaaaaaccuu cucaaacgga ugugacuacg uaucaaauaa aggcguagac     1440

acaguaagcg uaggaaacac ccuauacuac guuaacaaac aagaagggaa aucauuauac     1500

guaaaaggag aaccaauaau aaacuucuac gauccacucg uauucccauc cgacgaauuu     1560

gacgccagca uaucccaagu uaacgaaaaa auaaaccaau cacuugcauu uauacgaaaa     1620

ucugaugaac uucuccacaa cguaaaugca ggaaaaucca ccaccaauau aaugaucaca     1680

acuaucauca uaguaauaau cgucauuuua cuaucauuaa uagcaguugg ccuacuucua     1740

uacugcaaag caagauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  510
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  510
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagcc      120

aacgcgauca ccaccauccu aacggcaguc accuucugcu ucgcaucagg ccaaaacauc      180

acagaagagu ucuaccaaag cacaugcucc gccguaucca aaggcuaccu cagcgcccua      240

cgcacaggcu gguacacauc ugucaucacc auagaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cugacgccaa aguaaagcug aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuccaacu acucaugcaa uccaccccug caaccaacaa cagggcccgc      420

cgcgaacucc cccgcuucau gaacuacacu uuaaacaacg ccaaaaagac caacgucaca      480

cucagcaaga aacggaaacg acgauuccua ggguuucucc uaggcgucgg cucggcaauc      540

gccuccggcg ucgccguaag caaaguacua caccuagaag gcgaagugaa caaaaucaaa      600

agugcccuuc ucuccaccaa caaggccgua gucucucuau ccaacggagu cucaguccuc      660

accucaaagg uccucgaccu caaaaacuac aucgacaaac aacuacuccc cauugucaac      720

aagcagucau gcuccauauc aaacaucgaa accgucaucg aguuccaaca gaaaaacaac      780

cgacuccucg aaauaaccag agaguucucg gucaacgccg gcgucaccac cccagucagc      840

accuacaugc ucacuaacuc cgaacuccua ucccucauca acgacaugcc aauuaccaac      900

gaccaaaaga aacuaauguc gaacaacguu caaaucgucc gacaacaaag uuacuccauc      960

augagcauaa ucaaagaaga aguucuagcg uacgucgucc aacucccacu auacggcguc     1020

aucgacacuc cgugcuggaa acuccacaca ucaccccuau guacaaccaa cacaaaagaa     1080

ggcagcaaca ucugccucac ccgcaccgac cgaggguggu auugcgauaa cgcuggcagc     1140

gucuccuucu ucccccaagc cgaaaccugc aaaguccaau caaacagagu auucugcgac     1200

accaugaacu cccuuacucu cccuagcgaa gucaaccucu gcaacguuga cauauucaac     1260

cccaaauacg acugcaaaau caugaccucc aagaccgacg ucuccuccuc cgucaucaca     1320

ucucuaggug ccauugucuc cugcuacgga aaaaccaaau gcacagccuc caacaaaaac     1380

cgcggcauca uaaaaaccuu cuccaacggc ugcgacuacg ucaguaauaa aggcgucgac     1440

acgguauccg uugggaauac gcuuuacuac guaaauaaac aagaaggcaa aucccucuac     1500

gucaaaggug aacccaucau aaacuucuac gacccgcuug uguucccauc cgacgaguuc     1560

gacgccagca ucagccaggu caacgaaaag aucaaccaau cccuagccuu cauccgcaaa     1620

agcgacgaac uacuacacaa cgucaacgcc ggaaaaucca caaccaacau caugaucacc     1680

accaucauca ucgucaucau cguaauccua cucucucuca ucgccgucgg ccuccuacug     1740

uacuguaaag cccgauaggg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  511
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  511
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agauaaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  512
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  512
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  513
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  513
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  514
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  514
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  515
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  515
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  516
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  516
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  517
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  517
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cggugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  518
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  518
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaauac ucaaagccaa cgcaauaaca acaauacuaa cagcaguaac auucugcuuc      240

gcaucaggac aaaacaucac agaagaauuu uaccaaagua caugcagugc agucucuaaa      300

ggauaccuca gugccuuacg cacaggaugg uacacaucag uaauaacaau cgaacuuuca      360

aacauaaaag aaaacaaaug caauggaacc gacgccaaag uaaaacuaau caaacaagaa      420

cuagacaaau auaaaaaugc aguaacagaa uuacaacucc uaaugcaauc cacaccagca      480

acaaauaaca gagcaagacg agaacucccu cgauucauga auuacacauu aaacaacgca      540

aaaaaaacua acguaacuuu aucaaaaaaa agaaaacgua gauuucuagg auuccuacua      600

ggcguagggu ccgccauugc aucaggagua gcaguuagca aaguauuaca uuuagaagga      660

gaaguaaaua aaaucaaaag cgcacuacuc ucaaccaaca aagcaguagu aucacucuca      720

aacggaguau caguacuaac auccaaagua cucgaccuca aaaacuacau agacaaacaa      780

uuacuaccca uaguaaacaa acaaucaugc ucuauaucaa auaucgaaac aguaaucgaa      840

uuucaacaaa aaaacaaucg acuacuugaa auaacaagag aguucuccgu caaugccgga      900

gucaccacac cagucucaac auacaugcua accaacucug aacuccuauc acuaauaaau      960

gacaugccaa uaacaaacga ccaaaaaaaa cuaaugucaa auaacguaca aauaguacga     1020

caacaaaguu auuccauaau gaguauaauc aaagaagaag uguuagcaua cguaguccaa     1080

cuaccauuau auggaguaau agacacacca uguuggaaau uacacaccuc accacucugc     1140

acuaccaaua caaaagaagg cucaaauaua ugccuaacuc gcacagacag aggcugguac     1200

ugcgauaacg caggauccgu aucuuucuuu ccccaagcag aaacuugcaa aguacaauca     1260

aacagagucu ucugcgacac caugaauagu cucacauuac caucugaagu aaaccuaugu     1320

aacguagaua uauucaaucc aaaauacgac ugcaaaauaa ugacaucaaa aaccgacguc     1380

ucuagcagug uaaucacauc acuaggagca auaguaagcu gcuauggaaa aacaaaaugu     1440

acagcaucaa acaaaaacag gggaauaaua aaaaccuucu caaacggaug ugacuacgua     1500

ucaaauaaag gcguagacac aguaagcgua ggaaacaccc uauacuacgu uaacaaacaa     1560

gaagggaaau cauuauacgu aaaaggagaa ccaauaauaa acuucuacga uccacucgua     1620

uucccauccg acgaauuuga cgccagcaua ucccaaguua acgaaaaaau aaaccaauca     1680

cuugcauuua uacgaaaauc ugaugaacuu cuccacaacg uaaaugcagg aaaauccacc     1740

accaauauaa ugaucacaac uaucaucaua guaauaaucg ucauuuuacu aucauuaaua     1800

gcaguuggcc uacuucuaua cugcaaagca agauaaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  519
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  519
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagccaa cgcgaucacc accauccuaa cggcagucac cuucugcuuc      240

gcaucaggcc aaaacaucac agaagaguuc uaccaaagca caugcuccgc cguauccaaa      300

ggcuaccuca gcgcccuacg cacaggcugg uacacaucug ucaucaccau agaacucucc      360

aacaucaaag aaaacaaaug caacggcacu gacgccaaag uaaagcugau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuccaacuac ucaugcaauc caccccugca      480

accaacaaca gggcccgccg cgaacucccc cgcuucauga acuacacuuu aaacaacgcc      540

aaaaagacca acgucacacu cagcaagaaa cggaaacgac gauuccuagg guuucuccua      600

ggcgucggcu cggcaaucgc cuccggcguc gccguaagca aaguacuaca ccuagaaggc      660

gaagugaaca aaaucaaaag ugcccuucuc uccaccaaca aggccguagu cucucuaucc      720

aacggagucu caguccucac cucaaagguc cucgaccuca aaaacuacau cgacaaacaa      780

cuacucccca uugucaacaa gcagucaugc uccauaucaa acaucgaaac cgucaucgag      840

uuccaacaga aaaacaaccg acuccucgaa auaaccagag aguucucggu caacgccggc      900

gucaccaccc cagucagcac cuacaugcuc acuaacuccg aacuccuauc ccucaucaac      960

gacaugccaa uuaccaacga ccaaaagaaa cuaaugucga acaacguuca aaucguccga     1020

caacaaaguu acuccaucau gagcauaauc aaagaagaag uucuagcgua cgucguccaa     1080

cucccacuau acggcgucau cgacacuccg ugcuggaaac uccacacauc accccuaugu     1140

acaaccaaca caaaagaagg cagcaacauc ugccucaccc gcaccgaccg agggugguau     1200

ugcgauaacg cuggcagcgu cuccuucuuc ccccaagccg aaaccugcaa aguccaauca     1260

aacagaguau ucugcgacac caugaacucc cuuacucucc cuagcgaagu caaccucugc     1320

aacguugaca uauucaaccc caaauacgac ugcaaaauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucacauc ucuaggugcc auugucuccu gcuacggaaa aaccaaaugc     1440

acagccucca acaaaaaccg cggcaucaua aaaaccuucu ccaacggcug cgacuacguc     1500

aguaauaaag gcgucgacac gguauccguu gggaauacgc uuuacuacgu aaauaaacaa     1560

gaaggcaaau cccucuacgu caaaggugaa cccaucauaa acuucuacga cccgcuugug     1620

uucccauccg acgaguucga cgccagcauc agccagguca acgaaaagau caaccaaucc     1680

cuagccuuca uccgcaaaag cgacgaacua cuacacaacg ucaacgccgg aaaauccaca     1740

accaacauca ugaucaccac caucaucauc gucaucaucg uaauccuacu cucucucauc     1800

gccgucggcc uccuacugua cuguaaagcc cgauagggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  520
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  520
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gauaaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  521
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  521
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  522
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  522
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  523
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  523
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  524
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  524
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  525
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  525
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  526
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  526
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc ggugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  527
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  527
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauacu caaagccaac gcaauaacaa caauacuaac agcaguaaca      180

uucugcuucg caucaggaca aaacaucaca gaagaauuuu accaaaguac augcagugca      240

gucucuaaag gauaccucag ugccuuacgc acaggauggu acacaucagu aauaacaauc      300

gaacuuucaa acauaaaaga aaacaaaugc aauggaaccg acgccaaagu aaaacuaauc      360

aaacaagaac uagacaaaua uaaaaaugca guaacagaau uacaacuccu aaugcaaucc      420

acaccagcaa caaauaacag agcaagacga gaacucccuc gauucaugaa uuacacauua      480

aacaacgcaa aaaaaacuaa cguaacuuua ucaaaaaaaa gaaaacguag auuucuagga      540

uuccuacuag gcguaggguc cgccauugca ucaggaguag caguuagcaa aguauuacau      600

uuagaaggag aaguaaauaa aaucaaaagc gcacuacucu caaccaacaa agcaguagua      660

ucacucucaa acggaguauc aguacuaaca uccaaaguac ucgaccucaa aaacuacaua      720

gacaaacaau uacuacccau aguaaacaaa caaucaugcu cuauaucaaa uaucgaaaca      780

guaaucgaau uucaacaaaa aaacaaucga cuacuugaaa uaacaagaga guucuccguc      840

aaugccggag ucaccacacc agucucaaca uacaugcuaa ccaacucuga acuccuauca      900

cuaauaaaug acaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      960

auaguacgac aacaaaguua uuccauaaug aguauaauca aagaagaagu guuagcauac     1020

guaguccaac uaccauuaua uggaguaaua gacacaccau guuggaaauu acacaccuca     1080

ccacucugca cuaccaauac aaaagaaggc ucaaauauau gccuaacucg cacagacaga     1140

ggcugguacu gcgauaacgc aggauccgua ucuuucuuuc cccaagcaga aacuugcaaa     1200

guacaaucaa acagagucuu cugcgacacc augaauaguc ucacauuacc aucugaagua     1260

aaccuaugua acguagauau auucaaucca aaauacgacu gcaaaauaau gacaucaaaa     1320

accgacgucu cuagcagugu aaucacauca cuaggagcaa uaguaagcug cuauggaaaa     1380

acaaaaugua cagcaucaaa caaaaacagg ggaauaauaa aaaccuucuc aaacggaugu     1440

gacuacguau caaauaaagg cguagacaca guaagcguag gaaacacccu auacuacguu     1500

aacaaacaag aagggaaauc auuauacgua aaaggagaac caauaauaaa cuucuacgau     1560

ccacucguau ucccauccga cgaauuugac gccagcauau cccaaguuaa cgaaaaaaua     1620

aaccaaucac uugcauuuau acgaaaaucu gaugaacuuc uccacaacgu aaaugcagga     1680

aaauccacca ccaauauaau gaucacaacu aucaucauag uaauaaucgu cauuuuacua     1740

ucauuaauag caguuggccu acuucuauac ugcaaagcaa gauaaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  528
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  528
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagccaac gcgaucacca ccauccuaac ggcagucacc      180

uucugcuucg caucaggcca aaacaucaca gaagaguucu accaaagcac augcuccgcc      240

guauccaaag gcuaccucag cgcccuacgc acaggcuggu acacaucugu caucaccaua      300

gaacucucca acaucaaaga aaacaaaugc aacggcacug acgccaaagu aaagcugauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uccaacuacu caugcaaucc      420

accccugcaa ccaacaacag ggcccgccgc gaacuccccc gcuucaugaa cuacacuuua      480

aacaacgcca aaaagaccaa cgucacacuc agcaagaaac ggaaacgacg auuccuaggg      540

uuucuccuag gcgucggcuc ggcaaucgcc uccggcgucg ccguaagcaa aguacuacac      600

cuagaaggcg aagugaacaa aaucaaaagu gcccuucucu ccaccaacaa ggccguaguc      660

ucucuaucca acggagucuc aguccucacc ucaaaggucc ucgaccucaa aaacuacauc      720

gacaaacaac uacuccccau ugucaacaag cagucaugcu ccauaucaaa caucgaaacc      780

gucaucgagu uccaacagaa aaacaaccga cuccucgaaa uaaccagaga guucucgguc      840

aacgccggcg ucaccacccc agucagcacc uacaugcuca cuaacuccga acuccuaucc      900

cucaucaacg acaugccaau uaccaacgac caaaagaaac uaaugucgaa caacguucaa      960

aucguccgac aacaaaguua cuccaucaug agcauaauca aagaagaagu ucuagcguac     1020

gucguccaac ucccacuaua cggcgucauc gacacuccgu gcuggaaacu ccacacauca     1080

ccccuaugua caaccaacac aaaagaaggc agcaacaucu gccucacccg caccgaccga     1140

gggugguauu gcgauaacgc uggcagcguc uccuucuucc cccaagccga aaccugcaaa     1200

guccaaucaa acagaguauu cugcgacacc augaacuccc uuacucuccc uagcgaaguc     1260

aaccucugca acguugacau auucaacccc aaauacgacu gcaaaaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucacaucu cuaggugcca uugucuccug cuacggaaaa     1380

accaaaugca cagccuccaa caaaaaccgc ggcaucauaa aaaccuucuc caacggcugc     1440

gacuacguca guaauaaagg cgucgacacg guauccguug ggaauacgcu uuacuacgua     1500

aauaaacaag aaggcaaauc ccucuacguc aaaggugaac ccaucauaaa cuucuacgac     1560

ccgcuugugu ucccauccga cgaguucgac gccagcauca gccaggucaa cgaaaagauc     1620

aaccaauccc uagccuucau ccgcaaaagc gacgaacuac uacacaacgu caacgccgga     1680

aaauccacaa ccaacaucau gaucaccacc aucaucaucg ucaucaucgu aauccuacuc     1740

ucucucaucg ccgucggccu ccuacuguac uguaaagccc gauagggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  529
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  529
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  530
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  530
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  531
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  531
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  532
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  532
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  533
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  533
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccaggug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  534
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  534
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  535
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  535
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccggug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  536
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  536
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauacucaaa gccaacgcaa uaacaacaau acuaacagca      120

guaacauucu gcuucgcauc aggacaaaac aucacagaag aauuuuacca aaguacaugc      180

agugcagucu cuaaaggaua ccucagugcc uuacgcacag gaugguacac aucaguaaua      240

acaaucgaac uuucaaacau aaaagaaaac aaaugcaaug gaaccgacgc caaaguaaaa      300

cuaaucaaac aagaacuaga caaauauaaa aaugcaguaa cagaauuaca acuccuaaug      360

caauccacac cagcaacaaa uaacagagca agacgagaac ucccucgauu caugaauuac      420

acauuaaaca acgcaaaaaa aacuaacgua acuuuaucaa aaaaaagaaa acguagauuu      480

cuaggauucc uacuaggcgu aggguccgcc auugcaucag gaguagcagu uagcaaagua      540

uuacauuuag aaggagaagu aaauaaaauc aaaagcgcac uacucucaac caacaaagca      600

guaguaucac ucucaaacgg aguaucagua cuaacaucca aaguacucga ccucaaaaac      660

uacauagaca aacaauuacu acccauagua aacaaacaau caugcucuau aucaaauauc      720

gaaacaguaa ucgaauuuca acaaaaaaac aaucgacuac uugaaauaac aagagaguuc      780

uccgucaaug ccggagucac cacaccaguc ucaacauaca ugcuaaccaa cucugaacuc      840

cuaucacuaa uaaaugacau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      900

guacaaauag uacgacaaca aaguuauucc auaaugagua uaaucaaaga agaaguguua      960

gcauacguag uccaacuacc auuauaugga guaauagaca caccauguug gaaauuacac     1020

accucaccac ucugcacuac caauacaaaa gaaggcucaa auauaugccu aacucgcaca     1080

gacagaggcu gguacugcga uaacgcagga uccguaucuu ucuuucccca agcagaaacu     1140

ugcaaaguac aaucaaacag agucuucugc gacaccauga auagucucac auuaccaucu     1200

gaaguaaacc uauguaacgu agauauauuc aauccaaaau acgacugcaa aauaaugaca     1260

ucaaaaaccg acgucucuag caguguaauc acaucacuag gagcaauagu aagcugcuau     1320

ggaaaaacaa aauguacagc aucaaacaaa aacaggggaa uaauaaaaac cuucucaaac     1380

ggaugugacu acguaucaaa uaaaggcgua gacacaguaa gcguaggaaa cacccuauac     1440

uacguuaaca aacaagaagg gaaaucauua uacguaaaag gagaaccaau aauaaacuuc     1500

uacgauccac ucguauuccc auccgacgaa uuugacgcca gcauauccca aguuaacgaa     1560

aaaauaaacc aaucacuugc auuuauacga aaaucugaug aacuucucca caacguaaau     1620

gcaggaaaau ccaccaccaa uauaaugauc acaacuauca ucauaguaau aaucgucauu     1680

uuacuaucau uaauagcagu uggccuacuu cuauacugca aagcaagaua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  537
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  537
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gccaacgcga ucaccaccau ccuaacggca      120

gucaccuucu gcuucgcauc aggccaaaac aucacagaag aguucuacca aagcacaugc      180

uccgccguau ccaaaggcua ccucagcgcc cuacgcacag gcugguacac aucugucauc      240

accauagaac ucuccaacau caaagaaaac aaaugcaacg gcacugacgc caaaguaaag      300

cugaucaaac aagaacucga caaauacaaa aacgcaguca ccgaacucca acuacucaug      360

caauccaccc cugcaaccaa caacagggcc cgccgcgaac ucccccgcuu caugaacuac      420

acuuuaaaca acgccaaaaa gaccaacguc acacucagca agaaacggaa acgacgauuc      480

cuaggguuuc uccuaggcgu cggcucggca aucgccuccg gcgucgccgu aagcaaagua      540

cuacaccuag aaggcgaagu gaacaaaauc aaaagugccc uucucuccac caacaaggcc      600

guagucucuc uauccaacgg agucucaguc cucaccucaa agguccucga ccucaaaaac      660

uacaucgaca aacaacuacu ccccauuguc aacaagcagu caugcuccau aucaaacauc      720

gaaaccguca ucgaguucca acagaaaaac aaccgacucc ucgaaauaac cagagaguuc      780

ucggucaacg ccggcgucac caccccaguc agcaccuaca ugcucacuaa cuccgaacuc      840

cuaucccuca ucaacgacau gccaauuacc aacgaccaaa agaaacuaau gucgaacaac      900

guucaaaucg uccgacaaca aaguuacucc aucaugagca uaaucaaaga agaaguucua      960

gcguacgucg uccaacuccc acuauacggc gucaucgaca cuccgugcug gaaacuccac     1020

acaucacccc uauguacaac caacacaaaa gaaggcagca acaucugccu cacccgcacc     1080

gaccgagggu gguauugcga uaacgcuggc agcgucuccu ucuuccccca agccgaaacc     1140

ugcaaagucc aaucaaacag aguauucugc gacaccauga acucccuuac ucucccuagc     1200

gaagucaacc ucugcaacgu ugacauauuc aaccccaaau acgacugcaa aaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc acaucucuag gugccauugu cuccugcuac     1320

ggaaaaacca aaugcacagc cuccaacaaa aaccgcggca ucauaaaaac cuucuccaac     1380

ggcugcgacu acgucaguaa uaaaggcguc gacacgguau ccguugggaa uacgcuuuac     1440

uacguaaaua aacaagaagg caaaucccuc uacgucaaag gugaacccau cauaaacuuc     1500

uacgacccgc uuguguuccc auccgacgag uucgacgcca gcaucagcca ggucaacgaa     1560

aagaucaacc aaucccuagc cuucauccgc aaaagcgacg aacuacuaca caacgucaac     1620

gccggaaaau ccacaaccaa caucaugauc accaccauca ucaucgucau caucguaauc     1680

cuacucucuc ucaucgccgu cggccuccua cuguacugua aagcccgaua gggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  538
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  538
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      300

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      360

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      420

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      480

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      540

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      600

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      660

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      720

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      780

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      840

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      900

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      960

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc     1020

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu     1080

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua     1140

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1200

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1260

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1320

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1380

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1440

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1500

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1560

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1620

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1680

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1740

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1800

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1860

auugcuguug gacugcucuu auacuguaag gccagauaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  539
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  539
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      660

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      720

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      780

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      900

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      960

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc     1020

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc     1080

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc     1140

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1200

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1260

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1320

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1500

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1620

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1680

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1800

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1860

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  540
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  540
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      660

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      720

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      780

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      900

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      960

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc     1080

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc     1140

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1200

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1260

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1320

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1380

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1500

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1620

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1680

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1740

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1800

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1860

aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  541
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  541
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      600

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      660

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      720

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      780

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      840

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      900

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      960

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc     1080

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc     1140

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1200

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1260

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1320

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1500

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1560

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1620

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1680

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1740

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1800

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1860

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  542
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  542
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      600

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      660

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      720

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      780

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      840

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      900

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      960

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc     1020

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug     1080

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu     1140

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1200

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1260

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1320

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1380

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1440

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1500

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1560

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1620

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1680

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1740

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1800

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1860

aucgcugugg gccugcuucu guacugcaag gccaggugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  543
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  543
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      600

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      660

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      720

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      780

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      840

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      900

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      960

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug     1080

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug     1140

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1200

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1260

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1320

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1380

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1440

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1500

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1620

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1680

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1800

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1860

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  544
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  544
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      600

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      660

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      720

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      780

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      840

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      900

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      960

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc     1020

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu     1080

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug     1140

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1200

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1260

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1320

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1380

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1440

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1500

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1560

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1620

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1680

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1740

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1800

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1860

aucgcggugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  545
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  545
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaauuacuaa uacucaaagc caacgcaaua acaacaauac uaacagcagu aacauucugc      300

uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa guacaugcag ugcagucucu      360

aaaggauacc ucagugccuu acgcacagga ugguacacau caguaauaac aaucgaacuu      420

ucaaacauaa aagaaaacaa augcaaugga accgacgcca aaguaaaacu aaucaaacaa      480

gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac uccuaaugca auccacacca      540

gcaacaaaua acagagcaag acgagaacuc ccucgauuca ugaauuacac auuaaacaac      600

gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac guagauuucu aggauuccua      660

cuaggcguag gguccgccau ugcaucagga guagcaguua gcaaaguauu acauuuagaa      720

ggagaaguaa auaaaaucaa aagcgcacua cucucaacca acaaagcagu aguaucacuc      780

ucaaacggag uaucaguacu aacauccaaa guacucgacc ucaaaaacua cauagacaaa      840

caauuacuac ccauaguaaa caaacaauca ugcucuauau caaauaucga aacaguaauc      900

gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa gagaguucuc cgucaaugcc      960

ggagucacca caccagucuc aacauacaug cuaaccaacu cugaacuccu aucacuaaua     1020

aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu acaaauagua     1080

cgacaacaaa guuauuccau aaugaguaua aucaaagaag aaguguuagc auacguaguc     1140

caacuaccau uauauggagu aauagacaca ccauguugga aauuacacac cucaccacuc     1200

ugcacuacca auacaaaaga aggcucaaau auaugccuaa cucgcacaga cagaggcugg     1260

uacugcgaua acgcaggauc cguaucuuuc uuuccccaag cagaaacuug caaaguacaa     1320

ucaaacagag ucuucugcga caccaugaau agucucacau uaccaucuga aguaaaccua     1380

uguaacguag auauauucaa uccaaaauac gacugcaaaa uaaugacauc aaaaaccgac     1440

gucucuagca guguaaucac aucacuagga gcaauaguaa gcugcuaugg aaaaacaaaa     1500

uguacagcau caaacaaaaa caggggaaua auaaaaaccu ucucaaacgg augugacuac     1560

guaucaaaua aaggcguaga cacaguaagc guaggaaaca cccuauacua cguuaacaaa     1620

caagaaggga aaucauuaua cguaaaagga gaaccaauaa uaaacuucua cgauccacuc     1680

guauucccau ccgacgaauu ugacgccagc auaucccaag uuaacgaaaa aauaaaccaa     1740

ucacuugcau uuauacgaaa aucugaugaa cuucuccaca acguaaaugc aggaaaaucc     1800

accaccaaua uaaugaucac aacuaucauc auaguaauaa ucgucauuuu acuaucauua     1860

auagcaguug gccuacuucu auacugcaaa gcaagauaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  546
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  546
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuaa uccuaaaagc caacgcgauc accaccaucc uaacggcagu caccuucugc      300

uucgcaucag gccaaaacau cacagaagag uucuaccaaa gcacaugcuc cgccguaucc      360

aaaggcuacc ucagcgcccu acgcacaggc ugguacacau cugucaucac cauagaacuc      420

uccaacauca aagaaaacaa augcaacggc acugacgcca aaguaaagcu gaucaaacaa      480

gaacucgaca aauacaaaaa cgcagucacc gaacuccaac uacucaugca auccaccccu      540

gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca ugaacuacac uuuaaacaac      600

gccaaaaaga ccaacgucac acucagcaag aaacggaaac gacgauuccu aggguuucuc      660

cuaggcgucg gcucggcaau cgccuccggc gucgccguaa gcaaaguacu acaccuagaa      720

ggcgaaguga acaaaaucaa aagugcccuu cucuccacca acaaggccgu agucucucua      780

uccaacggag ucucaguccu caccucaaag guccucgacc ucaaaaacua caucgacaaa      840

caacuacucc ccauugucaa caagcaguca ugcuccauau caaacaucga aaccgucauc      900

gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca gagaguucuc ggucaacgcc      960

ggcgucacca ccccagucag caccuacaug cucacuaacu ccgaacuccu aucccucauc     1020

aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu cgaacaacgu ucaaaucguc     1080

cgacaacaaa guuacuccau caugagcaua aucaaagaag aaguucuagc guacgucguc     1140

caacucccac uauacggcgu caucgacacu ccgugcugga aacuccacac aucaccccua     1200

uguacaacca acacaaaaga aggcagcaac aucugccuca cccgcaccga ccgagggugg     1260

uauugcgaua acgcuggcag cgucuccuuc uucccccaag ccgaaaccug caaaguccaa     1320

ucaaacagag uauucugcga caccaugaac ucccuuacuc ucccuagcga agucaaccuc     1380

ugcaacguug acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1440

gucuccuccu ccgucaucac aucucuaggu gccauugucu ccugcuacgg aaaaaccaaa     1500

ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu ucuccaacgg cugcgacuac     1560

gucaguaaua aaggcgucga cacgguaucc guugggaaua cgcuuuacua cguaaauaaa     1620

caagaaggca aaucccucua cgucaaaggu gaacccauca uaaacuucua cgacccgcuu     1680

guguucccau ccgacgaguu cgacgccagc aucagccagg ucaacgaaaa gaucaaccaa     1740

ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca acgucaacgc cggaaaaucc     1800

acaaccaaca ucaugaucac caccaucauc aucgucauca ucguaauccu acucucucuc     1860

aucgccgucg gccuccuacu guacuguaaa gcccgauagg gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  547
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  547
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      120

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      180

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      240

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      300

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      360

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      420

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      480

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      540

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      600

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      660

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      720

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      780

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc      840

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu      900

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua      960

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1020

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1080

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1140

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1200

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1260

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1320

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1380

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1440

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1500

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1560

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1620

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1680

auugcuguug gacugcucuu auacuguaag gccagauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  548
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  548
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  549
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  549
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1140

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1560

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  550
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  550
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  551
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  551
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      600

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      720

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      780

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug      900

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu      960

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1020

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1080

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1140

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1200

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1260

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1320

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1380

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1440

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1500

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1560

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1620

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1680

aucgcugugg gccugcuucu guacugcaag gccaggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  552
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  552
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  553
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  553
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      600

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      720

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      780

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu      900

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug      960

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1020

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1080

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1140

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1200

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1260

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1320

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1380

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1440

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1500

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1560

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1680

aucgcggugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  554
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  554
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaauuacuaa uacucaaagc caacgcaaua acaacaauac uaacagcagu aacauucugc      120

uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa guacaugcag ugcagucucu      180

aaaggauacc ucagugccuu acgcacagga ugguacacau caguaauaac aaucgaacuu      240

ucaaacauaa aagaaaacaa augcaaugga accgacgcca aaguaaaacu aaucaaacaa      300

gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac uccuaaugca auccacacca      360

gcaacaaaua acagagcaag acgagaacuc ccucgauuca ugaauuacac auuaaacaac      420

gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac guagauuucu aggauuccua      480

cuaggcguag gguccgccau ugcaucagga guagcaguua gcaaaguauu acauuuagaa      540

ggagaaguaa auaaaaucaa aagcgcacua cucucaacca acaaagcagu aguaucacuc      600

ucaaacggag uaucaguacu aacauccaaa guacucgacc ucaaaaacua cauagacaaa      660

caauuacuac ccauaguaaa caaacaauca ugcucuauau caaauaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa gagaguucuc cgucaaugcc      780

ggagucacca caccagucuc aacauacaug cuaaccaacu cugaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu acaaauagua      900

cgacaacaaa guuauuccau aaugaguaua aucaaagaag aaguguuagc auacguaguc      960

caacuaccau uauauggagu aauagacaca ccauguugga aauuacacac cucaccacuc     1020

ugcacuacca auacaaaaga aggcucaaau auaugccuaa cucgcacaga cagaggcugg     1080

uacugcgaua acgcaggauc cguaucuuuc uuuccccaag cagaaacuug caaaguacaa     1140

ucaaacagag ucuucugcga caccaugaau agucucacau uaccaucuga aguaaaccua     1200

uguaacguag auauauucaa uccaaaauac gacugcaaaa uaaugacauc aaaaaccgac     1260

gucucuagca guguaaucac aucacuagga gcaauaguaa gcugcuaugg aaaaacaaaa     1320

uguacagcau caaacaaaaa caggggaaua auaaaaaccu ucucaaacgg augugacuac     1380

guaucaaaua aaggcguaga cacaguaagc guaggaaaca cccuauacua cguuaacaaa     1440

caagaaggga aaucauuaua cguaaaagga gaaccaauaa uaaacuucua cgauccacuc     1500

guauucccau ccgacgaauu ugacgccagc auaucccaag uuaacgaaaa aauaaaccaa     1560

ucacuugcau uuauacgaaa aucugaugaa cuucuccaca acguaaaugc aggaaaaucc     1620

accaccaaua uaaugaucac aacuaucauc auaguaauaa ucgucauuuu acuaucauua     1680

auagcaguug gccuacuucu auacugcaaa gcaagauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  555
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  555
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuaa uccuaaaagc caacgcgauc accaccaucc uaacggcagu caccuucugc      120

uucgcaucag gccaaaacau cacagaagag uucuaccaaa gcacaugcuc cgccguaucc      180

aaaggcuacc ucagcgcccu acgcacaggc ugguacacau cugucaucac cauagaacuc      240

uccaacauca aagaaaacaa augcaacggc acugacgcca aaguaaagcu gaucaaacaa      300

gaacucgaca aauacaaaaa cgcagucacc gaacuccaac uacucaugca auccaccccu      360

gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca ugaacuacac uuuaaacaac      420

gccaaaaaga ccaacgucac acucagcaag aaacggaaac gacgauuccu aggguuucuc      480

cuaggcgucg gcucggcaau cgccuccggc gucgccguaa gcaaaguacu acaccuagaa      540

ggcgaaguga acaaaaucaa aagugcccuu cucuccacca acaaggccgu agucucucua      600

uccaacggag ucucaguccu caccucaaag guccucgacc ucaaaaacua caucgacaaa      660

caacuacucc ccauugucaa caagcaguca ugcuccauau caaacaucga aaccgucauc      720

gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca gagaguucuc ggucaacgcc      780

ggcgucacca ccccagucag caccuacaug cucacuaacu ccgaacuccu aucccucauc      840

aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu cgaacaacgu ucaaaucguc      900

cgacaacaaa guuacuccau caugagcaua aucaaagaag aaguucuagc guacgucguc      960

caacucccac uauacggcgu caucgacacu ccgugcugga aacuccacac aucaccccua     1020

uguacaacca acacaaaaga aggcagcaac aucugccuca cccgcaccga ccgagggugg     1080

uauugcgaua acgcuggcag cgucuccuuc uucccccaag ccgaaaccug caaaguccaa     1140

ucaaacagag uauucugcga caccaugaac ucccuuacuc ucccuagcga agucaaccuc     1200

ugcaacguug acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac aucucuaggu gccauugucu ccugcuacgg aaaaaccaaa     1320

ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucaguaaua aaggcgucga cacgguaucc guugggaaua cgcuuuacua cguaaauaaa     1440

caagaaggca aaucccucua cgucaaaggu gaacccauca uaaacuucua cgacccgcuu     1500

guguucccau ccgacgaguu cgacgccagc aucagccagg ucaacgaaaa gaucaaccaa     1560

ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca acgucaacgc cggaaaaucc     1620

acaaccaaca ucaugaucac caccaucauc aucgucauca ucguaauccu acucucucuc     1680

aucgccgucg gccuccuacu guacuguaaa gcccgauagg gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  556
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  556
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagauaag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  557
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  557
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  558
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  558
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  559
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  559
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  560
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  560
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  561
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  561
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  562
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  562
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  563
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  563
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uacucaaagc caacgcaaua acaacaauac      120

uaacagcagu aacauucugc uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa      180

guacaugcag ugcagucucu aaaggauacc ucagugccuu acgcacagga ugguacacau      240

caguaauaac aaucgaacuu ucaaacauaa aagaaaacaa augcaaugga accgacgcca      300

aaguaaaacu aaucaaacaa gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac      360

uccuaaugca auccacacca gcaacaaaua acagagcaag acgagaacuc ccucgauuca      420

ugaauuacac auuaaacaac gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac      480

guagauuucu aggauuccua cuaggcguag gguccgccau ugcaucagga guagcaguua      540

gcaaaguauu acauuuagaa ggagaaguaa auaaaaucaa aagcgcacua cucucaacca      600

acaaagcagu aguaucacuc ucaaacggag uaucaguacu aacauccaaa guacucgacc      660

ucaaaaacua cauagacaaa caauuacuac ccauaguaaa caaacaauca ugcucuauau      720

caaauaucga aacaguaauc gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa      780

gagaguucuc cgucaaugcc ggagucacca caccagucuc aacauacaug cuaaccaacu      840

cugaacuccu aucacuaaua aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu      900

caaauaacgu acaaauagua cgacaacaaa guuauuccau aaugaguaua aucaaagaag      960

aaguguuagc auacguaguc caacuaccau uauauggagu aauagacaca ccauguugga     1020

aauuacacac cucaccacuc ugcacuacca auacaaaaga aggcucaaau auaugccuaa     1080

cucgcacaga cagaggcugg uacugcgaua acgcaggauc cguaucuuuc uuuccccaag     1140

cagaaacuug caaaguacaa ucaaacagag ucuucugcga caccaugaau agucucacau     1200

uaccaucuga aguaaaccua uguaacguag auauauucaa uccaaaauac gacugcaaaa     1260

uaaugacauc aaaaaccgac gucucuagca guguaaucac aucacuagga gcaauaguaa     1320

gcugcuaugg aaaaacaaaa uguacagcau caaacaaaaa caggggaaua auaaaaaccu     1380

ucucaaacgg augugacuac guaucaaaua aaggcguaga cacaguaagc guaggaaaca     1440

cccuauacua cguuaacaaa caagaaggga aaucauuaua cguaaaagga gaaccaauaa     1500

uaaacuucua cgauccacuc guauucccau ccgacgaauu ugacgccagc auaucccaag     1560

uuaacgaaaa aauaaaccaa ucacuugcau uuauacgaaa aucugaugaa cuucuccaca     1620

acguaaaugc aggaaaaucc accaccaaua uaaugaucac aacuaucauc auaguaauaa     1680

ucgucauuuu acuaucauua auagcaguug gccuacuucu auacugcaaa gcaagauaag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  564
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  564
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc caacgcgauc accaccaucc      120

uaacggcagu caccuucugc uucgcaucag gccaaaacau cacagaagag uucuaccaaa      180

gcacaugcuc cgccguaucc aaaggcuacc ucagcgcccu acgcacaggc ugguacacau      240

cugucaucac cauagaacuc uccaacauca aagaaaacaa augcaacggc acugacgcca      300

aaguaaagcu gaucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuccaac      360

uacucaugca auccaccccu gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca      420

ugaacuacac uuuaaacaac gccaaaaaga ccaacgucac acucagcaag aaacggaaac      480

gacgauuccu aggguuucuc cuaggcgucg gcucggcaau cgccuccggc gucgccguaa      540

gcaaaguacu acaccuagaa ggcgaaguga acaaaaucaa aagugcccuu cucuccacca      600

acaaggccgu agucucucua uccaacggag ucucaguccu caccucaaag guccucgacc      660

ucaaaaacua caucgacaaa caacuacucc ccauugucaa caagcaguca ugcuccauau      720

caaacaucga aaccgucauc gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca      780

gagaguucuc ggucaacgcc ggcgucacca ccccagucag caccuacaug cucacuaacu      840

ccgaacuccu aucccucauc aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu      900

cgaacaacgu ucaaaucguc cgacaacaaa guuacuccau caugagcaua aucaaagaag      960

aaguucuagc guacgucguc caacucccac uauacggcgu caucgacacu ccgugcugga     1020

aacuccacac aucaccccua uguacaacca acacaaaaga aggcagcaac aucugccuca     1080

cccgcaccga ccgagggugg uauugcgaua acgcuggcag cgucuccuuc uucccccaag     1140

ccgaaaccug caaaguccaa ucaaacagag uauucugcga caccaugaac ucccuuacuc     1200

ucccuagcga agucaaccuc ugcaacguug acauauucaa ccccaaauac gacugcaaaa     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac aucucuaggu gccauugucu     1320

ccugcuacgg aaaaaccaaa ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu     1380

ucuccaacgg cugcgacuac gucaguaaua aaggcgucga cacgguaucc guugggaaua     1440

cgcuuuacua cguaaauaaa caagaaggca aaucccucua cgucaaaggu gaacccauca     1500

uaaacuucua cgacccgcuu guguucccau ccgacgaguu cgacgccagc aucagccagg     1560

ucaacgaaaa gaucaaccaa ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca     1620

acgucaacgc cggaaaaucc acaaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucguaauccu acucucucuc aucgccgucg gccuccuacu guacuguaaa gcccgauagg     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  565
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  565
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagauaag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  566
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  566
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  567
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  567
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  568
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  568
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  569
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  569
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  570
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  570
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  571
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  571
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  572
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  572
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uacucaaagc caacgcaaua acaacaauac      120

uaacagcagu aacauucugc uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa      180

guacaugcag ugcagucucu aaaggauacc ucagugccuu acgcacagga ugguacacau      240

caguaauaac aaucgaacuu ucaaacauaa aagaaaacaa augcaaugga accgacgcca      300

aaguaaaacu aaucaaacaa gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac      360

uccuaaugca auccacacca gcaacaaaua acagagcaag acgagaacuc ccucgauuca      420

ugaauuacac auuaaacaac gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac      480

guagauuucu aggauuccua cuaggcguag gguccgccau ugcaucagga guagcaguua      540

gcaaaguauu acauuuagaa ggagaaguaa auaaaaucaa aagcgcacua cucucaacca      600

acaaagcagu aguaucacuc ucaaacggag uaucaguacu aacauccaaa guacucgacc      660

ucaaaaacua cauagacaaa caauuacuac ccauaguaaa caaacaauca ugcucuauau      720

caaauaucga aacaguaauc gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa      780

gagaguucuc cgucaaugcc ggagucacca caccagucuc aacauacaug cuaaccaacu      840

cugaacuccu aucacuaaua aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu      900

caaauaacgu acaaauagua cgacaacaaa guuauuccau aaugaguaua aucaaagaag      960

aaguguuagc auacguaguc caacuaccau uauauggagu aauagacaca ccauguugga     1020

aauuacacac cucaccacuc ugcacuacca auacaaaaga aggcucaaau auaugccuaa     1080

cucgcacaga cagaggcugg uacugcgaua acgcaggauc cguaucuuuc uuuccccaag     1140

cagaaacuug caaaguacaa ucaaacagag ucuucugcga caccaugaau agucucacau     1200

uaccaucuga aguaaaccua uguaacguag auauauucaa uccaaaauac gacugcaaaa     1260

uaaugacauc aaaaaccgac gucucuagca guguaaucac aucacuagga gcaauaguaa     1320

gcugcuaugg aaaaacaaaa uguacagcau caaacaaaaa caggggaaua auaaaaaccu     1380

ucucaaacgg augugacuac guaucaaaua aaggcguaga cacaguaagc guaggaaaca     1440

cccuauacua cguuaacaaa caagaaggga aaucauuaua cguaaaagga gaaccaauaa     1500

uaaacuucua cgauccacuc guauucccau ccgacgaauu ugacgccagc auaucccaag     1560

uuaacgaaaa aauaaaccaa ucacuugcau uuauacgaaa aucugaugaa cuucuccaca     1620

acguaaaugc aggaaaaucc accaccaaua uaaugaucac aacuaucauc auaguaauaa     1680

ucgucauuuu acuaucauua auagcaguug gccuacuucu auacugcaaa gcaagauaag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  573
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  573
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc caacgcgauc accaccaucc      120

uaacggcagu caccuucugc uucgcaucag gccaaaacau cacagaagag uucuaccaaa      180

gcacaugcuc cgccguaucc aaaggcuacc ucagcgcccu acgcacaggc ugguacacau      240

cugucaucac cauagaacuc uccaacauca aagaaaacaa augcaacggc acugacgcca      300

aaguaaagcu gaucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuccaac      360

uacucaugca auccaccccu gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca      420

ugaacuacac uuuaaacaac gccaaaaaga ccaacgucac acucagcaag aaacggaaac      480

gacgauuccu aggguuucuc cuaggcgucg gcucggcaau cgccuccggc gucgccguaa      540

gcaaaguacu acaccuagaa ggcgaaguga acaaaaucaa aagugcccuu cucuccacca      600

acaaggccgu agucucucua uccaacggag ucucaguccu caccucaaag guccucgacc      660

ucaaaaacua caucgacaaa caacuacucc ccauugucaa caagcaguca ugcuccauau      720

caaacaucga aaccgucauc gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca      780

gagaguucuc ggucaacgcc ggcgucacca ccccagucag caccuacaug cucacuaacu      840

ccgaacuccu aucccucauc aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu      900

cgaacaacgu ucaaaucguc cgacaacaaa guuacuccau caugagcaua aucaaagaag      960

aaguucuagc guacgucguc caacucccac uauacggcgu caucgacacu ccgugcugga     1020

aacuccacac aucaccccua uguacaacca acacaaaaga aggcagcaac aucugccuca     1080

cccgcaccga ccgagggugg uauugcgaua acgcuggcag cgucuccuuc uucccccaag     1140

ccgaaaccug caaaguccaa ucaaacagag uauucugcga caccaugaac ucccuuacuc     1200

ucccuagcga agucaaccuc ugcaacguug acauauucaa ccccaaauac gacugcaaaa     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac aucucuaggu gccauugucu     1320

ccugcuacgg aaaaaccaaa ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu     1380

ucuccaacgg cugcgacuac gucaguaaua aaggcgucga cacgguaucc guugggaaua     1440

cgcuuuacua cguaaauaaa caagaaggca aaucccucua cgucaaaggu gaacccauca     1500

uaaacuucua cgacccgcuu guguucccau ccgacgaguu cgacgccagc aucagccagg     1560

ucaacgaaaa gaucaaccaa ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca     1620

acgucaacgc cggaaaaucc acaaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucguaauccu acucucucuc aucgccgucg gccuccuacu guacuguaaa gcccgauagg     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  574
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  574
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gauaaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  575
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  575
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  576
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  576
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  577
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  577
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  578
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  578
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  579
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  579
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  580
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  580
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc ggugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  581
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  581
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauacu caaagccaac gcaauaacaa caauacuaac agcaguaaca      180

uucugcuucg caucaggaca aaacaucaca gaagaauuuu accaaaguac augcagugca      240

gucucuaaag gauaccucag ugccuuacgc acaggauggu acacaucagu aauaacaauc      300

gaacuuucaa acauaaaaga aaacaaaugc aauggaaccg acgccaaagu aaaacuaauc      360

aaacaagaac uagacaaaua uaaaaaugca guaacagaau uacaacuccu aaugcaaucc      420

acaccagcaa caaauaacag agcaagacga gaacucccuc gauucaugaa uuacacauua      480

aacaacgcaa aaaaaacuaa cguaacuuua ucaaaaaaaa gaaaacguag auuucuagga      540

uuccuacuag gcguaggguc cgccauugca ucaggaguag caguuagcaa aguauuacau      600

uuagaaggag aaguaaauaa aaucaaaagc gcacuacucu caaccaacaa agcaguagua      660

ucacucucaa acggaguauc aguacuaaca uccaaaguac ucgaccucaa aaacuacaua      720

gacaaacaau uacuacccau aguaaacaaa caaucaugcu cuauaucaaa uaucgaaaca      780

guaaucgaau uucaacaaaa aaacaaucga cuacuugaaa uaacaagaga guucuccguc      840

aaugccggag ucaccacacc agucucaaca uacaugcuaa ccaacucuga acuccuauca      900

cuaauaaaug acaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      960

auaguacgac aacaaaguua uuccauaaug aguauaauca aagaagaagu guuagcauac     1020

guaguccaac uaccauuaua uggaguaaua gacacaccau guuggaaauu acacaccuca     1080

ccacucugca cuaccaauac aaaagaaggc ucaaauauau gccuaacucg cacagacaga     1140

ggcugguacu gcgauaacgc aggauccgua ucuuucuuuc cccaagcaga aacuugcaaa     1200

guacaaucaa acagagucuu cugcgacacc augaauaguc ucacauuacc aucugaagua     1260

aaccuaugua acguagauau auucaaucca aaauacgacu gcaaaauaau gacaucaaaa     1320

accgacgucu cuagcagugu aaucacauca cuaggagcaa uaguaagcug cuauggaaaa     1380

acaaaaugua cagcaucaaa caaaaacagg ggaauaauaa aaaccuucuc aaacggaugu     1440

gacuacguau caaauaaagg cguagacaca guaagcguag gaaacacccu auacuacguu     1500

aacaaacaag aagggaaauc auuauacgua aaaggagaac caauaauaaa cuucuacgau     1560

ccacucguau ucccauccga cgaauuugac gccagcauau cccaaguuaa cgaaaaaaua     1620

aaccaaucac uugcauuuau acgaaaaucu gaugaacuuc uccacaacgu aaaugcagga     1680

aaauccacca ccaauauaau gaucacaacu aucaucauag uaauaaucgu cauuuuacua     1740

ucauuaauag caguuggccu acuucuauac ugcaaagcaa gauaaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  582
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  582
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagccaac gcgaucacca ccauccuaac ggcagucacc      180

uucugcuucg caucaggcca aaacaucaca gaagaguucu accaaagcac augcuccgcc      240

guauccaaag gcuaccucag cgcccuacgc acaggcuggu acacaucugu caucaccaua      300

gaacucucca acaucaaaga aaacaaaugc aacggcacug acgccaaagu aaagcugauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uccaacuacu caugcaaucc      420

accccugcaa ccaacaacag ggcccgccgc gaacuccccc gcuucaugaa cuacacuuua      480

aacaacgcca aaaagaccaa cgucacacuc agcaagaaac ggaaacgacg auuccuaggg      540

uuucuccuag gcgucggcuc ggcaaucgcc uccggcgucg ccguaagcaa aguacuacac      600

cuagaaggcg aagugaacaa aaucaaaagu gcccuucucu ccaccaacaa ggccguaguc      660

ucucuaucca acggagucuc aguccucacc ucaaaggucc ucgaccucaa aaacuacauc      720

gacaaacaac uacuccccau ugucaacaag cagucaugcu ccauaucaaa caucgaaacc      780

gucaucgagu uccaacagaa aaacaaccga cuccucgaaa uaaccagaga guucucgguc      840

aacgccggcg ucaccacccc agucagcacc uacaugcuca cuaacuccga acuccuaucc      900

cucaucaacg acaugccaau uaccaacgac caaaagaaac uaaugucgaa caacguucaa      960

aucguccgac aacaaaguua cuccaucaug agcauaauca aagaagaagu ucuagcguac     1020

gucguccaac ucccacuaua cggcgucauc gacacuccgu gcuggaaacu ccacacauca     1080

ccccuaugua caaccaacac aaaagaaggc agcaacaucu gccucacccg caccgaccga     1140

gggugguauu gcgauaacgc uggcagcguc uccuucuucc cccaagccga aaccugcaaa     1200

guccaaucaa acagaguauu cugcgacacc augaacuccc uuacucuccc uagcgaaguc     1260

aaccucugca acguugacau auucaacccc aaauacgacu gcaaaaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucacaucu cuaggugcca uugucuccug cuacggaaaa     1380

accaaaugca cagccuccaa caaaaaccgc ggcaucauaa aaaccuucuc caacggcugc     1440

gacuacguca guaauaaagg cgucgacacg guauccguug ggaauacgcu uuacuacgua     1500

aauaaacaag aaggcaaauc ccucuacguc aaaggugaac ccaucauaaa cuucuacgac     1560

ccgcuugugu ucccauccga cgaguucgac gccagcauca gccaggucaa cgaaaagauc     1620

aaccaauccc uagccuucau ccgcaaaagc gacgaacuac uacacaacgu caacgccgga     1680

aaauccacaa ccaacaucau gaucaccacc aucaucaucg ucaucaucgu aauccuacuc     1740

ucucucaucg ccgucggccu ccuacuguac uguaaagccc gauagggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  583
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  583
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagauaagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  584
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  584
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  585
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  585
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  586
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  586
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  587
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  587
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  588
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  588
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  589
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  589
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  590
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  590
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau acucaaagcc      120

aacgcaauaa caacaauacu aacagcagua acauucugcu ucgcaucagg acaaaacauc      180

acagaagaau uuuaccaaag uacaugcagu gcagucucua aaggauaccu cagugccuua      240

cgcacaggau gguacacauc aguaauaaca aucgaacuuu caaacauaaa agaaaacaaa      300

ugcaauggaa ccgacgccaa aguaaaacua aucaaacaag aacuagacaa auauaaaaau      360

gcaguaacag aauuacaacu ccuaaugcaa uccacaccag caacaaauaa cagagcaaga      420

cgagaacucc cucgauucau gaauuacaca uuaaacaacg caaaaaaaac uaacguaacu      480

uuaucaaaaa aaagaaaacg uagauuucua ggauuccuac uaggcguagg guccgccauu      540

gcaucaggag uagcaguuag caaaguauua cauuuagaag gagaaguaaa uaaaaucaaa      600

agcgcacuac ucucaaccaa caaagcagua guaucacucu caaacggagu aucaguacua      660

acauccaaag uacucgaccu caaaaacuac auagacaaac aauuacuacc cauaguaaac      720

aaacaaucau gcucuauauc aaauaucgaa acaguaaucg aauuucaaca aaaaaacaau      780

cgacuacuug aaauaacaag agaguucucc gucaaugccg gagucaccac accagucuca      840

acauacaugc uaaccaacuc ugaacuccua ucacuaauaa augacaugcc aauaacaaac      900

gaccaaaaaa aacuaauguc aaauaacgua caaauaguac gacaacaaag uuauuccaua      960

augaguauaa ucaaagaaga aguguuagca uacguagucc aacuaccauu auauggagua     1020

auagacacac cauguuggaa auuacacacc ucaccacucu gcacuaccaa uacaaaagaa     1080

ggcucaaaua uaugccuaac ucgcacagac agaggcuggu acugcgauaa cgcaggaucc     1140

guaucuuucu uuccccaagc agaaacuugc aaaguacaau caaacagagu cuucugcgac     1200

accaugaaua gucucacauu accaucugaa guaaaccuau guaacguaga uauauucaau     1260

ccaaaauacg acugcaaaau aaugacauca aaaaccgacg ucucuagcag uguaaucaca     1320

ucacuaggag caauaguaag cugcuaugga aaaacaaaau guacagcauc aaacaaaaac     1380

aggggaauaa uaaaaaccuu cucaaacgga ugugacuacg uaucaaauaa aggcguagac     1440

acaguaagcg uaggaaacac ccuauacuac guuaacaaac aagaagggaa aucauuauac     1500

guaaaaggag aaccaauaau aaacuucuac gauccacucg uauucccauc cgacgaauuu     1560

gacgccagca uaucccaagu uaacgaaaaa auaaaccaau cacuugcauu uauacgaaaa     1620

ucugaugaac uucuccacaa cguaaaugca ggaaaaucca ccaccaauau aaugaucaca     1680

acuaucauca uaguaauaau cgucauuuua cuaucauuaa uagcaguugg ccuacuucua     1740

uacugcaaag caagauaagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  591
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  591
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagcc      120

aacgcgauca ccaccauccu aacggcaguc accuucugcu ucgcaucagg ccaaaacauc      180

acagaagagu ucuaccaaag cacaugcucc gccguaucca aaggcuaccu cagcgcccua      240

cgcacaggcu gguacacauc ugucaucacc auagaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cugacgccaa aguaaagcug aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuccaacu acucaugcaa uccaccccug caaccaacaa cagggcccgc      420

cgcgaacucc cccgcuucau gaacuacacu uuaaacaacg ccaaaaagac caacgucaca      480

cucagcaaga aacggaaacg acgauuccua ggguuucucc uaggcgucgg cucggcaauc      540

gccuccggcg ucgccguaag caaaguacua caccuagaag gcgaagugaa caaaaucaaa      600

agugcccuuc ucuccaccaa caaggccgua gucucucuau ccaacggagu cucaguccuc      660

accucaaagg uccucgaccu caaaaacuac aucgacaaac aacuacuccc cauugucaac      720

aagcagucau gcuccauauc aaacaucgaa accgucaucg aguuccaaca gaaaaacaac      780

cgacuccucg aaauaaccag agaguucucg gucaacgccg gcgucaccac cccagucagc      840

accuacaugc ucacuaacuc cgaacuccua ucccucauca acgacaugcc aauuaccaac      900

gaccaaaaga aacuaauguc gaacaacguu caaaucgucc gacaacaaag uuacuccauc      960

augagcauaa ucaaagaaga aguucuagcg uacgucgucc aacucccacu auacggcguc     1020

aucgacacuc cgugcuggaa acuccacaca ucaccccuau guacaaccaa cacaaaagaa     1080

ggcagcaaca ucugccucac ccgcaccgac cgaggguggu auugcgauaa cgcuggcagc     1140

gucuccuucu ucccccaagc cgaaaccugc aaaguccaau caaacagagu auucugcgac     1200

accaugaacu cccuuacucu cccuagcgaa gucaaccucu gcaacguuga cauauucaac     1260

cccaaauacg acugcaaaau caugaccucc aagaccgacg ucuccuccuc cgucaucaca     1320

ucucuaggug ccauugucuc cugcuacgga aaaaccaaau gcacagccuc caacaaaaac     1380

cgcggcauca uaaaaaccuu cuccaacggc ugcgacuacg ucaguaauaa aggcgucgac     1440

acgguauccg uugggaauac gcuuuacuac guaaauaaac aagaaggcaa aucccucuac     1500

gucaaaggug aacccaucau aaacuucuac gacccgcuug uguucccauc cgacgaguuc     1560

gacgccagca ucagccaggu caacgaaaag aucaaccaau cccuagccuu cauccgcaaa     1620

agcgacgaac uacuacacaa cgucaacgcc ggaaaaucca caaccaacau caugaucacc     1680

accaucauca ucgucaucau cguaauccua cucucucuca ucgccgucgg ccuccuacug     1740

uacuguaaag cccgauaggg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  592
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  592
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gauaaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  593
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  593
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  594
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  594
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  595
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  595
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  596
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  596
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  597
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  597
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  598
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  598
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc ggugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  599
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  599
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauacu caaagccaac gcaauaacaa caauacuaac agcaguaaca      180

uucugcuucg caucaggaca aaacaucaca gaagaauuuu accaaaguac augcagugca      240

gucucuaaag gauaccucag ugccuuacgc acaggauggu acacaucagu aauaacaauc      300

gaacuuucaa acauaaaaga aaacaaaugc aauggaaccg acgccaaagu aaaacuaauc      360

aaacaagaac uagacaaaua uaaaaaugca guaacagaau uacaacuccu aaugcaaucc      420

acaccagcaa caaauaacag agcaagacga gaacucccuc gauucaugaa uuacacauua      480

aacaacgcaa aaaaaacuaa cguaacuuua ucaaaaaaaa gaaaacguag auuucuagga      540

uuccuacuag gcguaggguc cgccauugca ucaggaguag caguuagcaa aguauuacau      600

uuagaaggag aaguaaauaa aaucaaaagc gcacuacucu caaccaacaa agcaguagua      660

ucacucucaa acggaguauc aguacuaaca uccaaaguac ucgaccucaa aaacuacaua      720

gacaaacaau uacuacccau aguaaacaaa caaucaugcu cuauaucaaa uaucgaaaca      780

guaaucgaau uucaacaaaa aaacaaucga cuacuugaaa uaacaagaga guucuccguc      840

aaugccggag ucaccacacc agucucaaca uacaugcuaa ccaacucuga acuccuauca      900

cuaauaaaug acaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      960

auaguacgac aacaaaguua uuccauaaug aguauaauca aagaagaagu guuagcauac     1020

guaguccaac uaccauuaua uggaguaaua gacacaccau guuggaaauu acacaccuca     1080

ccacucugca cuaccaauac aaaagaaggc ucaaauauau gccuaacucg cacagacaga     1140

ggcugguacu gcgauaacgc aggauccgua ucuuucuuuc cccaagcaga aacuugcaaa     1200

guacaaucaa acagagucuu cugcgacacc augaauaguc ucacauuacc aucugaagua     1260

aaccuaugua acguagauau auucaaucca aaauacgacu gcaaaauaau gacaucaaaa     1320

accgacgucu cuagcagugu aaucacauca cuaggagcaa uaguaagcug cuauggaaaa     1380

acaaaaugua cagcaucaaa caaaaacagg ggaauaauaa aaaccuucuc aaacggaugu     1440

gacuacguau caaauaaagg cguagacaca guaagcguag gaaacacccu auacuacguu     1500

aacaaacaag aagggaaauc auuauacgua aaaggagaac caauaauaaa cuucuacgau     1560

ccacucguau ucccauccga cgaauuugac gccagcauau cccaaguuaa cgaaaaaaua     1620

aaccaaucac uugcauuuau acgaaaaucu gaugaacuuc uccacaacgu aaaugcagga     1680

aaauccacca ccaauauaau gaucacaacu aucaucauag uaauaaucgu cauuuuacua     1740

ucauuaauag caguuggccu acuucuauac ugcaaagcaa gauaaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  600
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  600
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagccaac gcgaucacca ccauccuaac ggcagucacc      180

uucugcuucg caucaggcca aaacaucaca gaagaguucu accaaagcac augcuccgcc      240

guauccaaag gcuaccucag cgcccuacgc acaggcuggu acacaucugu caucaccaua      300

gaacucucca acaucaaaga aaacaaaugc aacggcacug acgccaaagu aaagcugauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uccaacuacu caugcaaucc      420

accccugcaa ccaacaacag ggcccgccgc gaacuccccc gcuucaugaa cuacacuuua      480

aacaacgcca aaaagaccaa cgucacacuc agcaagaaac ggaaacgacg auuccuaggg      540

uuucuccuag gcgucggcuc ggcaaucgcc uccggcgucg ccguaagcaa aguacuacac      600

cuagaaggcg aagugaacaa aaucaaaagu gcccuucucu ccaccaacaa ggccguaguc      660

ucucuaucca acggagucuc aguccucacc ucaaaggucc ucgaccucaa aaacuacauc      720

gacaaacaac uacuccccau ugucaacaag cagucaugcu ccauaucaaa caucgaaacc      780

gucaucgagu uccaacagaa aaacaaccga cuccucgaaa uaaccagaga guucucgguc      840

aacgccggcg ucaccacccc agucagcacc uacaugcuca cuaacuccga acuccuaucc      900

cucaucaacg acaugccaau uaccaacgac caaaagaaac uaaugucgaa caacguucaa      960

aucguccgac aacaaaguua cuccaucaug agcauaauca aagaagaagu ucuagcguac     1020

gucguccaac ucccacuaua cggcgucauc gacacuccgu gcuggaaacu ccacacauca     1080

ccccuaugua caaccaacac aaaagaaggc agcaacaucu gccucacccg caccgaccga     1140

gggugguauu gcgauaacgc uggcagcguc uccuucuucc cccaagccga aaccugcaaa     1200

guccaaucaa acagaguauu cugcgacacc augaacuccc uuacucuccc uagcgaaguc     1260

aaccucugca acguugacau auucaacccc aaauacgacu gcaaaaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucacaucu cuaggugcca uugucuccug cuacggaaaa     1380

accaaaugca cagccuccaa caaaaaccgc ggcaucauaa aaaccuucuc caacggcugc     1440

gacuacguca guaauaaagg cgucgacacg guauccguug ggaauacgcu uuacuacgua     1500

aauaaacaag aaggcaaauc ccucuacguc aaaggugaac ccaucauaaa cuucuacgac     1560

ccgcuugugu ucccauccga cgaguucgac gccagcauca gccaggucaa cgaaaagauc     1620

aaccaauccc uagccuucau ccgcaaaagc gacgaacuac uacacaacgu caacgccgga     1680

aaauccacaa ccaacaucau gaucaccacc aucaucaucg ucaucaucgu aauccuacuc     1740

ucucucaucg ccgucggccu ccuacuguac uguaaagccc gauagggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  601
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  601
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagauaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  602
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  602
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  603
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  603
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  604
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  604
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  605
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  605
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  606
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  606
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  607
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  607
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  608
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  608
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau acucaaagcc      120

aacgcaauaa caacaauacu aacagcagua acauucugcu ucgcaucagg acaaaacauc      180

acagaagaau uuuaccaaag uacaugcagu gcagucucua aaggauaccu cagugccuua      240

cgcacaggau gguacacauc aguaauaaca aucgaacuuu caaacauaaa agaaaacaaa      300

ugcaauggaa ccgacgccaa aguaaaacua aucaaacaag aacuagacaa auauaaaaau      360

gcaguaacag aauuacaacu ccuaaugcaa uccacaccag caacaaauaa cagagcaaga      420

cgagaacucc cucgauucau gaauuacaca uuaaacaacg caaaaaaaac uaacguaacu      480

uuaucaaaaa aaagaaaacg uagauuucua ggauuccuac uaggcguagg guccgccauu      540

gcaucaggag uagcaguuag caaaguauua cauuuagaag gagaaguaaa uaaaaucaaa      600

agcgcacuac ucucaaccaa caaagcagua guaucacucu caaacggagu aucaguacua      660

acauccaaag uacucgaccu caaaaacuac auagacaaac aauuacuacc cauaguaaac      720

aaacaaucau gcucuauauc aaauaucgaa acaguaaucg aauuucaaca aaaaaacaau      780

cgacuacuug aaauaacaag agaguucucc gucaaugccg gagucaccac accagucuca      840

acauacaugc uaaccaacuc ugaacuccua ucacuaauaa augacaugcc aauaacaaac      900

gaccaaaaaa aacuaauguc aaauaacgua caaauaguac gacaacaaag uuauuccaua      960

augaguauaa ucaaagaaga aguguuagca uacguagucc aacuaccauu auauggagua     1020

auagacacac cauguuggaa auuacacacc ucaccacucu gcacuaccaa uacaaaagaa     1080

ggcucaaaua uaugccuaac ucgcacagac agaggcuggu acugcgauaa cgcaggaucc     1140

guaucuuucu uuccccaagc agaaacuugc aaaguacaau caaacagagu cuucugcgac     1200

accaugaaua gucucacauu accaucugaa guaaaccuau guaacguaga uauauucaau     1260

ccaaaauacg acugcaaaau aaugacauca aaaaccgacg ucucuagcag uguaaucaca     1320

ucacuaggag caauaguaag cugcuaugga aaaacaaaau guacagcauc aaacaaaaac     1380

aggggaauaa uaaaaaccuu cucaaacgga ugugacuacg uaucaaauaa aggcguagac     1440

acaguaagcg uaggaaacac ccuauacuac guuaacaaac aagaagggaa aucauuauac     1500

guaaaaggag aaccaauaau aaacuucuac gauccacucg uauucccauc cgacgaauuu     1560

gacgccagca uaucccaagu uaacgaaaaa auaaaccaau cacuugcauu uauacgaaaa     1620

ucugaugaac uucuccacaa cguaaaugca ggaaaaucca ccaccaauau aaugaucaca     1680

acuaucauca uaguaauaau cgucauuuua cuaucauuaa uagcaguugg ccuacuucua     1740

uacugcaaag caagauaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  609
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  609
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagcc      120

aacgcgauca ccaccauccu aacggcaguc accuucugcu ucgcaucagg ccaaaacauc      180

acagaagagu ucuaccaaag cacaugcucc gccguaucca aaggcuaccu cagcgcccua      240

cgcacaggcu gguacacauc ugucaucacc auagaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cugacgccaa aguaaagcug aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuccaacu acucaugcaa uccaccccug caaccaacaa cagggcccgc      420

cgcgaacucc cccgcuucau gaacuacacu uuaaacaacg ccaaaaagac caacgucaca      480

cucagcaaga aacggaaacg acgauuccua ggguuucucc uaggcgucgg cucggcaauc      540

gccuccggcg ucgccguaag caaaguacua caccuagaag gcgaagugaa caaaaucaaa      600

agugcccuuc ucuccaccaa caaggccgua gucucucuau ccaacggagu cucaguccuc      660

accucaaagg uccucgaccu caaaaacuac aucgacaaac aacuacuccc cauugucaac      720

aagcagucau gcuccauauc aaacaucgaa accgucaucg aguuccaaca gaaaaacaac      780

cgacuccucg aaauaaccag agaguucucg gucaacgccg gcgucaccac cccagucagc      840

accuacaugc ucacuaacuc cgaacuccua ucccucauca acgacaugcc aauuaccaac      900

gaccaaaaga aacuaauguc gaacaacguu caaaucgucc gacaacaaag uuacuccauc      960

augagcauaa ucaaagaaga aguucuagcg uacgucgucc aacucccacu auacggcguc     1020

aucgacacuc cgugcuggaa acuccacaca ucaccccuau guacaaccaa cacaaaagaa     1080

ggcagcaaca ucugccucac ccgcaccgac cgaggguggu auugcgauaa cgcuggcagc     1140

gucuccuucu ucccccaagc cgaaaccugc aaaguccaau caaacagagu auucugcgac     1200

accaugaacu cccuuacucu cccuagcgaa gucaaccucu gcaacguuga cauauucaac     1260

cccaaauacg acugcaaaau caugaccucc aagaccgacg ucuccuccuc cgucaucaca     1320

ucucuaggug ccauugucuc cugcuacgga aaaaccaaau gcacagccuc caacaaaaac     1380

cgcggcauca uaaaaaccuu cuccaacggc ugcgacuacg ucaguaauaa aggcgucgac     1440

acgguauccg uugggaauac gcuuuacuac guaaauaaac aagaaggcaa aucccucuac     1500

gucaaaggug aacccaucau aaacuucuac gacccgcuug uguucccauc cgacgaguuc     1560

gacgccagca ucagccaggu caacgaaaag aucaaccaau cccuagccuu cauccgcaaa     1620

agcgacgaac uacuacacaa cgucaacgcc ggaaaaucca caaccaacau caugaucacc     1680

accaucauca ucgucaucau cguaauccua cucucucuca ucgccgucgg ccuccuacug     1740

uacuguaaag cccgauaggg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  610
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  610
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagauaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  611
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  611
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  612
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  612
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  613
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  613
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  614
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  614
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  615
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  615
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  616
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  616
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  617
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  617
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau acucaaagcc      120

aacgcaauaa caacaauacu aacagcagua acauucugcu ucgcaucagg acaaaacauc      180

acagaagaau uuuaccaaag uacaugcagu gcagucucua aaggauaccu cagugccuua      240

cgcacaggau gguacacauc aguaauaaca aucgaacuuu caaacauaaa agaaaacaaa      300

ugcaauggaa ccgacgccaa aguaaaacua aucaaacaag aacuagacaa auauaaaaau      360

gcaguaacag aauuacaacu ccuaaugcaa uccacaccag caacaaauaa cagagcaaga      420

cgagaacucc cucgauucau gaauuacaca uuaaacaacg caaaaaaaac uaacguaacu      480

uuaucaaaaa aaagaaaacg uagauuucua ggauuccuac uaggcguagg guccgccauu      540

gcaucaggag uagcaguuag caaaguauua cauuuagaag gagaaguaaa uaaaaucaaa      600

agcgcacuac ucucaaccaa caaagcagua guaucacucu caaacggagu aucaguacua      660

acauccaaag uacucgaccu caaaaacuac auagacaaac aauuacuacc cauaguaaac      720

aaacaaucau gcucuauauc aaauaucgaa acaguaaucg aauuucaaca aaaaaacaau      780

cgacuacuug aaauaacaag agaguucucc gucaaugccg gagucaccac accagucuca      840

acauacaugc uaaccaacuc ugaacuccua ucacuaauaa augacaugcc aauaacaaac      900

gaccaaaaaa aacuaauguc aaauaacgua caaauaguac gacaacaaag uuauuccaua      960

augaguauaa ucaaagaaga aguguuagca uacguagucc aacuaccauu auauggagua     1020

auagacacac cauguuggaa auuacacacc ucaccacucu gcacuaccaa uacaaaagaa     1080

ggcucaaaua uaugccuaac ucgcacagac agaggcuggu acugcgauaa cgcaggaucc     1140

guaucuuucu uuccccaagc agaaacuugc aaaguacaau caaacagagu cuucugcgac     1200

accaugaaua gucucacauu accaucugaa guaaaccuau guaacguaga uauauucaau     1260

ccaaaauacg acugcaaaau aaugacauca aaaaccgacg ucucuagcag uguaaucaca     1320

ucacuaggag caauaguaag cugcuaugga aaaacaaaau guacagcauc aaacaaaaac     1380

aggggaauaa uaaaaaccuu cucaaacgga ugugacuacg uaucaaauaa aggcguagac     1440

acaguaagcg uaggaaacac ccuauacuac guuaacaaac aagaagggaa aucauuauac     1500

guaaaaggag aaccaauaau aaacuucuac gauccacucg uauucccauc cgacgaauuu     1560

gacgccagca uaucccaagu uaacgaaaaa auaaaccaau cacuugcauu uauacgaaaa     1620

ucugaugaac uucuccacaa cguaaaugca ggaaaaucca ccaccaauau aaugaucaca     1680

acuaucauca uaguaauaau cgucauuuua cuaucauuaa uagcaguugg ccuacuucua     1740

uacugcaaag caagauaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  618
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  618
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagcc      120

aacgcgauca ccaccauccu aacggcaguc accuucugcu ucgcaucagg ccaaaacauc      180

acagaagagu ucuaccaaag cacaugcucc gccguaucca aaggcuaccu cagcgcccua      240

cgcacaggcu gguacacauc ugucaucacc auagaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cugacgccaa aguaaagcug aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuccaacu acucaugcaa uccaccccug caaccaacaa cagggcccgc      420

cgcgaacucc cccgcuucau gaacuacacu uuaaacaacg ccaaaaagac caacgucaca      480

cucagcaaga aacggaaacg acgauuccua ggguuucucc uaggcgucgg cucggcaauc      540

gccuccggcg ucgccguaag caaaguacua caccuagaag gcgaagugaa caaaaucaaa      600

agugcccuuc ucuccaccaa caaggccgua gucucucuau ccaacggagu cucaguccuc      660

accucaaagg uccucgaccu caaaaacuac aucgacaaac aacuacuccc cauugucaac      720

aagcagucau gcuccauauc aaacaucgaa accgucaucg aguuccaaca gaaaaacaac      780

cgacuccucg aaauaaccag agaguucucg gucaacgccg gcgucaccac cccagucagc      840

accuacaugc ucacuaacuc cgaacuccua ucccucauca acgacaugcc aauuaccaac      900

gaccaaaaga aacuaauguc gaacaacguu caaaucgucc gacaacaaag uuacuccauc      960

augagcauaa ucaaagaaga aguucuagcg uacgucgucc aacucccacu auacggcguc     1020

aucgacacuc cgugcuggaa acuccacaca ucaccccuau guacaaccaa cacaaaagaa     1080

ggcagcaaca ucugccucac ccgcaccgac cgaggguggu auugcgauaa cgcuggcagc     1140

gucuccuucu ucccccaagc cgaaaccugc aaaguccaau caaacagagu auucugcgac     1200

accaugaacu cccuuacucu cccuagcgaa gucaaccucu gcaacguuga cauauucaac     1260

cccaaauacg acugcaaaau caugaccucc aagaccgacg ucuccuccuc cgucaucaca     1320

ucucuaggug ccauugucuc cugcuacgga aaaaccaaau gcacagccuc caacaaaaac     1380

cgcggcauca uaaaaaccuu cuccaacggc ugcgacuacg ucaguaauaa aggcgucgac     1440

acgguauccg uugggaauac gcuuuacuac guaaauaaac aagaaggcaa aucccucuac     1500

gucaaaggug aacccaucau aaacuucuac gacccgcuug uguucccauc cgacgaguuc     1560

gacgccagca ucagccaggu caacgaaaag aucaaccaau cccuagccuu cauccgcaaa     1620

agcgacgaac uacuacacaa cgucaacgcc ggaaaaucca caaccaacau caugaucacc     1680

accaucauca ucgucaucau cguaauccua cucucucuca ucgccgucgg ccuccuacug     1740

uacuguaaag cccgauaggg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  619
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  619
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagau aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  620
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  620
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  621
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  621
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgcu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  622
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  622
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  623
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  623
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  624
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  624
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  625
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  625
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  626
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  626
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauacucaa agccaacgca      120

auaacaacaa uacuaacagc aguaacauuc ugcuucgcau caggacaaaa caucacagaa      180

gaauuuuacc aaaguacaug cagugcaguc ucuaaaggau accucagugc cuuacgcaca      240

ggaugguaca caucaguaau aacaaucgaa cuuucaaaca uaaaagaaaa caaaugcaau      300

ggaaccgacg ccaaaguaaa acuaaucaaa caagaacuag acaaauauaa aaaugcagua      360

acagaauuac aacuccuaau gcaauccaca ccagcaacaa auaacagagc aagacgagaa      420

cucccucgau ucaugaauua cacauuaaac aacgcaaaaa aaacuaacgu aacuuuauca      480

aaaaaaagaa aacguagauu ucuaggauuc cuacuaggcg uaggguccgc cauugcauca      540

ggaguagcag uuagcaaagu auuacauuua gaaggagaag uaaauaaaau caaaagcgca      600

cuacucucaa ccaacaaagc aguaguauca cucucaaacg gaguaucagu acuaacaucc      660

aaaguacucg accucaaaaa cuacauagac aaacaauuac uacccauagu aaacaaacaa      720

ucaugcucua uaucaaauau cgaaacagua aucgaauuuc aacaaaaaaa caaucgacua      780

cuugaaauaa caagagaguu cuccgucaau gccggaguca ccacaccagu cucaacauac      840

augcuaacca acucugaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa      900

aaaaaacuaa ugucaaauaa cguacaaaua guacgacaac aaaguuauuc cauaaugagu      960

auaaucaaag aagaaguguu agcauacgua guccaacuac cauuauaugg aguaauagac     1020

acaccauguu ggaaauuaca caccucacca cucugcacua ccaauacaaa agaaggcuca     1080

aauauaugcc uaacucgcac agacagaggc ugguacugcg auaacgcagg auccguaucu     1140

uucuuucccc aagcagaaac uugcaaagua caaucaaaca gagucuucug cgacaccaug     1200

aauagucuca cauuaccauc ugaaguaaac cuauguaacg uagauauauu caauccaaaa     1260

uacgacugca aaauaaugac aucaaaaacc gacgucucua gcaguguaau cacaucacua     1320

ggagcaauag uaagcugcua uggaaaaaca aaauguacag caucaaacaa aaacagggga     1380

auaauaaaaa ccuucucaaa cggaugugac uacguaucaa auaaaggcgu agacacagua     1440

agcguaggaa acacccuaua cuacguuaac aaacaagaag ggaaaucauu auacguaaaa     1500

ggagaaccaa uaauaaacuu cuacgaucca cucguauucc cauccgacga auuugacgcc     1560

agcauauccc aaguuaacga aaaaauaaac caaucacuug cauuuauacg aaaaucugau     1620

gaacuucucc acaacguaaa ugcaggaaaa uccaccacca auauaaugau cacaacuauc     1680

aucauaguaa uaaucgucau uuuacuauca uuaauagcag uuggccuacu ucuauacugc     1740

aaagcaagau aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  627
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  627
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agccaacgcg      120

aucaccacca uccuaacggc agucaccuuc ugcuucgcau caggccaaaa caucacagaa      180

gaguucuacc aaagcacaug cuccgccgua uccaaaggcu accucagcgc ccuacgcaca      240

ggcugguaca caucugucau caccauagaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacugacg ccaaaguaaa gcugaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacucc aacuacucau gcaauccacc ccugcaacca acaacagggc ccgccgcgaa      420

cucccccgcu ucaugaacua cacuuuaaac aacgccaaaa agaccaacgu cacacucagc      480

aagaaacgga aacgacgauu ccuaggguuu cuccuaggcg ucggcucggc aaucgccucc      540

ggcgucgccg uaagcaaagu acuacaccua gaaggcgaag ugaacaaaau caaaagugcc      600

cuucucucca ccaacaaggc cguagucucu cuauccaacg gagucucagu ccucaccuca      660

aagguccucg accucaaaaa cuacaucgac aaacaacuac uccccauugu caacaagcag      720

ucaugcucca uaucaaacau cgaaaccguc aucgaguucc aacagaaaaa caaccgacuc      780

cucgaaauaa ccagagaguu cucggucaac gccggcguca ccaccccagu cagcaccuac      840

augcucacua acuccgaacu ccuaucccuc aucaacgaca ugccaauuac caacgaccaa      900

aagaaacuaa ugucgaacaa cguucaaauc guccgacaac aaaguuacuc caucaugagc      960

auaaucaaag aagaaguucu agcguacguc guccaacucc cacuauacgg cgucaucgac     1020

acuccgugcu ggaaacucca cacaucaccc cuauguacaa ccaacacaaa agaaggcagc     1080

aacaucugcc ucacccgcac cgaccgaggg ugguauugcg auaacgcugg cagcgucucc     1140

uucuuccccc aagccgaaac cugcaaaguc caaucaaaca gaguauucug cgacaccaug     1200

aacucccuua cucucccuag cgaagucaac cucugcaacg uugacauauu caaccccaaa     1260

uacgacugca aaaucaugac cuccaagacc gacgucuccu ccuccgucau cacaucucua     1320

ggugccauug ucuccugcua cggaaaaacc aaaugcacag ccuccaacaa aaaccgcggc     1380

aucauaaaaa ccuucuccaa cggcugcgac uacgucagua auaaaggcgu cgacacggua     1440

uccguuggga auacgcuuua cuacguaaau aaacaagaag gcaaaucccu cuacgucaaa     1500

ggugaaccca ucauaaacuu cuacgacccg cuuguguucc cauccgacga guucgacgcc     1560

agcaucagcc aggucaacga aaagaucaac caaucccuag ccuucauccg caaaagcgac     1620

gaacuacuac acaacgucaa cgccggaaaa uccacaacca acaucaugau caccaccauc     1680

aucaucguca ucaucguaau ccuacucucu cucaucgccg ucggccuccu acuguacugu     1740

aaagcccgau agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  628
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  628
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  629
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  629
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  630
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  630
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  631
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  631
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  632
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  632
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccaggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  633
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  633
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  634
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  634
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  635
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  635
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauacucaaa      120

gccaacgcaa uaacaacaau acuaacagca guaacauucu gcuucgcauc aggacaaaac      180

aucacagaag aauuuuacca aaguacaugc agugcagucu cuaaaggaua ccucagugcc      240

uuacgcacag gaugguacac aucaguaaua acaaucgaac uuucaaacau aaaagaaaac      300

aaaugcaaug gaaccgacgc caaaguaaaa cuaaucaaac aagaacuaga caaauauaaa      360

aaugcaguaa cagaauuaca acuccuaaug caauccacac cagcaacaaa uaacagagca      420

agacgagaac ucccucgauu caugaauuac acauuaaaca acgcaaaaaa aacuaacgua      480

acuuuaucaa aaaaaagaaa acguagauuu cuaggauucc uacuaggcgu aggguccgcc      540

auugcaucag gaguagcagu uagcaaagua uuacauuuag aaggagaagu aaauaaaauc      600

aaaagcgcac uacucucaac caacaaagca guaguaucac ucucaaacgg aguaucagua      660

cuaacaucca aaguacucga ccucaaaaac uacauagaca aacaauuacu acccauagua      720

aacaaacaau caugcucuau aucaaauauc gaaacaguaa ucgaauuuca acaaaaaaac      780

aaucgacuac uugaaauaac aagagaguuc uccgucaaug ccggagucac cacaccaguc      840

ucaacauaca ugcuaaccaa cucugaacuc cuaucacuaa uaaaugacau gccaauaaca      900

aacgaccaaa aaaaacuaau gucaaauaac guacaaauag uacgacaaca aaguuauucc      960

auaaugagua uaaucaaaga agaaguguua gcauacguag uccaacuacc auuauaugga     1020

guaauagaca caccauguug gaaauuacac accucaccac ucugcacuac caauacaaaa     1080

gaaggcucaa auauaugccu aacucgcaca gacagaggcu gguacugcga uaacgcagga     1140

uccguaucuu ucuuucccca agcagaaacu ugcaaaguac aaucaaacag agucuucugc     1200

gacaccauga auagucucac auuaccaucu gaaguaaacc uauguaacgu agauauauuc     1260

aauccaaaau acgacugcaa aauaaugaca ucaaaaaccg acgucucuag caguguaauc     1320

acaucacuag gagcaauagu aagcugcuau ggaaaaacaa aauguacagc aucaaacaaa     1380

aacaggggaa uaauaaaaac cuucucaaac ggaugugacu acguaucaaa uaaaggcgua     1440

gacacaguaa gcguaggaaa cacccuauac uacguuaaca aacaagaagg gaaaucauua     1500

uacguaaaag gagaaccaau aauaaacuuc uacgauccac ucguauuccc auccgacgaa     1560

uuugacgcca gcauauccca aguuaacgaa aaaauaaacc aaucacuugc auuuauacga     1620

aaaucugaug aacuucucca caacguaaau gcaggaaaau ccaccaccaa uauaaugauc     1680

acaacuauca ucauaguaau aaucgucauu uuacuaucau uaauagcagu uggccuacuu     1740

cuauacugca aagcaagaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  636
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  636
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gccaacgcga ucaccaccau ccuaacggca gucaccuucu gcuucgcauc aggccaaaac      180

aucacagaag aguucuacca aagcacaugc uccgccguau ccaaaggcua ccucagcgcc      240

cuacgcacag gcugguacac aucugucauc accauagaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacugacgc caaaguaaag cugaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacucca acuacucaug caauccaccc cugcaaccaa caacagggcc      420

cgccgcgaac ucccccgcuu caugaacuac acuuuaaaca acgccaaaaa gaccaacguc      480

acacucagca agaaacggaa acgacgauuc cuaggguuuc uccuaggcgu cggcucggca      540

aucgccuccg gcgucgccgu aagcaaagua cuacaccuag aaggcgaagu gaacaaaauc      600

aaaagugccc uucucuccac caacaaggcc guagucucuc uauccaacgg agucucaguc      660

cucaccucaa agguccucga ccucaaaaac uacaucgaca aacaacuacu ccccauuguc      720

aacaagcagu caugcuccau aucaaacauc gaaaccguca ucgaguucca acagaaaaac      780

aaccgacucc ucgaaauaac cagagaguuc ucggucaacg ccggcgucac caccccaguc      840

agcaccuaca ugcucacuaa cuccgaacuc cuaucccuca ucaacgacau gccaauuacc      900

aacgaccaaa agaaacuaau gucgaacaac guucaaaucg uccgacaaca aaguuacucc      960

aucaugagca uaaucaaaga agaaguucua gcguacgucg uccaacuccc acuauacggc     1020

gucaucgaca cuccgugcug gaaacuccac acaucacccc uauguacaac caacacaaaa     1080

gaaggcagca acaucugccu cacccgcacc gaccgagggu gguauugcga uaacgcuggc     1140

agcgucuccu ucuuccccca agccgaaacc ugcaaagucc aaucaaacag aguauucugc     1200

gacaccauga acucccuuac ucucccuagc gaagucaacc ucugcaacgu ugacauauuc     1260

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

acaucucuag gugccauugu cuccugcuac ggaaaaacca aaugcacagc cuccaacaaa     1380

aaccgcggca ucauaaaaac cuucuccaac ggcugcgacu acgucaguaa uaaaggcguc     1440

gacacgguau ccguugggaa uacgcuuuac uacguaaaua aacaagaagg caaaucccuc     1500

uacgucaaag gugaacccau cauaaacuuc uacgacccgc uuguguuccc auccgacgag     1560

uucgacgcca gcaucagcca ggucaacgaa aagaucaacc aaucccuagc cuucauccgc     1620

aaaagcgacg aacuacuaca caacgucaac gccggaaaau ccacaaccaa caucaugauc     1680

accaccauca ucaucgucau caucguaauc cuacucucuc ucaucgccgu cggccuccua     1740

cuguacugua aagcccgaua gggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  637
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  637
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagau aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  638
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  638
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  639
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  639
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgcu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  640
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  640
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  641
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  641
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  642
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  642
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  643
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  643
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  644
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  644
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauacucaa agccaacgca      120

auaacaacaa uacuaacagc aguaacauuc ugcuucgcau caggacaaaa caucacagaa      180

gaauuuuacc aaaguacaug cagugcaguc ucuaaaggau accucagugc cuuacgcaca      240

ggaugguaca caucaguaau aacaaucgaa cuuucaaaca uaaaagaaaa caaaugcaau      300

ggaaccgacg ccaaaguaaa acuaaucaaa caagaacuag acaaauauaa aaaugcagua      360

acagaauuac aacuccuaau gcaauccaca ccagcaacaa auaacagagc aagacgagaa      420

cucccucgau ucaugaauua cacauuaaac aacgcaaaaa aaacuaacgu aacuuuauca      480

aaaaaaagaa aacguagauu ucuaggauuc cuacuaggcg uaggguccgc cauugcauca      540

ggaguagcag uuagcaaagu auuacauuua gaaggagaag uaaauaaaau caaaagcgca      600

cuacucucaa ccaacaaagc aguaguauca cucucaaacg gaguaucagu acuaacaucc      660

aaaguacucg accucaaaaa cuacauagac aaacaauuac uacccauagu aaacaaacaa      720

ucaugcucua uaucaaauau cgaaacagua aucgaauuuc aacaaaaaaa caaucgacua      780

cuugaaauaa caagagaguu cuccgucaau gccggaguca ccacaccagu cucaacauac      840

augcuaacca acucugaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa      900

aaaaaacuaa ugucaaauaa cguacaaaua guacgacaac aaaguuauuc cauaaugagu      960

auaaucaaag aagaaguguu agcauacgua guccaacuac cauuauaugg aguaauagac     1020

acaccauguu ggaaauuaca caccucacca cucugcacua ccaauacaaa agaaggcuca     1080

aauauaugcc uaacucgcac agacagaggc ugguacugcg auaacgcagg auccguaucu     1140

uucuuucccc aagcagaaac uugcaaagua caaucaaaca gagucuucug cgacaccaug     1200

aauagucuca cauuaccauc ugaaguaaac cuauguaacg uagauauauu caauccaaaa     1260

uacgacugca aaauaaugac aucaaaaacc gacgucucua gcaguguaau cacaucacua     1320

ggagcaauag uaagcugcua uggaaaaaca aaauguacag caucaaacaa aaacagggga     1380

auaauaaaaa ccuucucaaa cggaugugac uacguaucaa auaaaggcgu agacacagua     1440

agcguaggaa acacccuaua cuacguuaac aaacaagaag ggaaaucauu auacguaaaa     1500

ggagaaccaa uaauaaacuu cuacgaucca cucguauucc cauccgacga auuugacgcc     1560

agcauauccc aaguuaacga aaaaauaaac caaucacuug cauuuauacg aaaaucugau     1620

gaacuucucc acaacguaaa ugcaggaaaa uccaccacca auauaaugau cacaacuauc     1680

aucauaguaa uaaucgucau uuuacuauca uuaauagcag uuggccuacu ucuauacugc     1740

aaagcaagau aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  645
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  645
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agccaacgcg      120

aucaccacca uccuaacggc agucaccuuc ugcuucgcau caggccaaaa caucacagaa      180

gaguucuacc aaagcacaug cuccgccgua uccaaaggcu accucagcgc ccuacgcaca      240

ggcugguaca caucugucau caccauagaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacugacg ccaaaguaaa gcugaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacucc aacuacucau gcaauccacc ccugcaacca acaacagggc ccgccgcgaa      420

cucccccgcu ucaugaacua cacuuuaaac aacgccaaaa agaccaacgu cacacucagc      480

aagaaacgga aacgacgauu ccuaggguuu cuccuaggcg ucggcucggc aaucgccucc      540

ggcgucgccg uaagcaaagu acuacaccua gaaggcgaag ugaacaaaau caaaagugcc      600

cuucucucca ccaacaaggc cguagucucu cuauccaacg gagucucagu ccucaccuca      660

aagguccucg accucaaaaa cuacaucgac aaacaacuac uccccauugu caacaagcag      720

ucaugcucca uaucaaacau cgaaaccguc aucgaguucc aacagaaaaa caaccgacuc      780

cucgaaauaa ccagagaguu cucggucaac gccggcguca ccaccccagu cagcaccuac      840

augcucacua acuccgaacu ccuaucccuc aucaacgaca ugccaauuac caacgaccaa      900

aagaaacuaa ugucgaacaa cguucaaauc guccgacaac aaaguuacuc caucaugagc      960

auaaucaaag aagaaguucu agcguacguc guccaacucc cacuauacgg cgucaucgac     1020

acuccgugcu ggaaacucca cacaucaccc cuauguacaa ccaacacaaa agaaggcagc     1080

aacaucugcc ucacccgcac cgaccgaggg ugguauugcg auaacgcugg cagcgucucc     1140

uucuuccccc aagccgaaac cugcaaaguc caaucaaaca gaguauucug cgacaccaug     1200

aacucccuua cucucccuag cgaagucaac cucugcaacg uugacauauu caaccccaaa     1260

uacgacugca aaaucaugac cuccaagacc gacgucuccu ccuccgucau cacaucucua     1320

ggugccauug ucuccugcua cggaaaaacc aaaugcacag ccuccaacaa aaaccgcggc     1380

aucauaaaaa ccuucuccaa cggcugcgac uacgucagua auaaaggcgu cgacacggua     1440

uccguuggga auacgcuuua cuacguaaau aaacaagaag gcaaaucccu cuacgucaaa     1500

ggugaaccca ucauaaacuu cuacgacccg cuuguguucc cauccgacga guucgacgcc     1560

agcaucagcc aggucaacga aaagaucaac caaucccuag ccuucauccg caaaagcgac     1620

gaacuacuac acaacgucaa cgccggaaaa uccacaacca acaucaugau caccaccauc     1680

aucaucguca ucaucguaau ccuacucucu cucaucgccg ucggccuccu acuguacugu     1740

aaagcccgau agggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  646
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  646
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agauaaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  647
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  647
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  648
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  648
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  649
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  649
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  650
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  650
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  651
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  651
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  652
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  652
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cggugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  653
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  653
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaauac ucaaagccaa cgcaauaaca acaauacuaa cagcaguaac auucugcuuc      240

gcaucaggac aaaacaucac agaagaauuu uaccaaagua caugcagugc agucucuaaa      300

ggauaccuca gugccuuacg cacaggaugg uacacaucag uaauaacaau cgaacuuuca      360

aacauaaaag aaaacaaaug caauggaacc gacgccaaag uaaaacuaau caaacaagaa      420

cuagacaaau auaaaaaugc aguaacagaa uuacaacucc uaaugcaauc cacaccagca      480

acaaauaaca gagcaagacg agaacucccu cgauucauga auuacacauu aaacaacgca      540

aaaaaaacua acguaacuuu aucaaaaaaa agaaaacgua gauuucuagg auuccuacua      600

ggcguagggu ccgccauugc aucaggagua gcaguuagca aaguauuaca uuuagaagga      660

gaaguaaaua aaaucaaaag cgcacuacuc ucaaccaaca aagcaguagu aucacucuca      720

aacggaguau caguacuaac auccaaagua cucgaccuca aaaacuacau agacaaacaa      780

uuacuaccca uaguaaacaa acaaucaugc ucuauaucaa auaucgaaac aguaaucgaa      840

uuucaacaaa aaaacaaucg acuacuugaa auaacaagag aguucuccgu caaugccgga      900

gucaccacac cagucucaac auacaugcua accaacucug aacuccuauc acuaauaaau      960

gacaugccaa uaacaaacga ccaaaaaaaa cuaaugucaa auaacguaca aauaguacga     1020

caacaaaguu auuccauaau gaguauaauc aaagaagaag uguuagcaua cguaguccaa     1080

cuaccauuau auggaguaau agacacacca uguuggaaau uacacaccuc accacucugc     1140

acuaccaaua caaaagaagg cucaaauaua ugccuaacuc gcacagacag aggcugguac     1200

ugcgauaacg caggauccgu aucuuucuuu ccccaagcag aaacuugcaa aguacaauca     1260

aacagagucu ucugcgacac caugaauagu cucacauuac caucugaagu aaaccuaugu     1320

aacguagaua uauucaaucc aaaauacgac ugcaaaauaa ugacaucaaa aaccgacguc     1380

ucuagcagug uaaucacauc acuaggagca auaguaagcu gcuauggaaa aacaaaaugu     1440

acagcaucaa acaaaaacag gggaauaaua aaaaccuucu caaacggaug ugacuacgua     1500

ucaaauaaag gcguagacac aguaagcgua ggaaacaccc uauacuacgu uaacaaacaa     1560

gaagggaaau cauuauacgu aaaaggagaa ccaauaauaa acuucuacga uccacucgua     1620

uucccauccg acgaauuuga cgccagcaua ucccaaguua acgaaaaaau aaaccaauca     1680

cuugcauuua uacgaaaauc ugaugaacuu cuccacaacg uaaaugcagg aaaauccacc     1740

accaauauaa ugaucacaac uaucaucaua guaauaaucg ucauuuuacu aucauuaaua     1800

gcaguuggcc uacuucuaua cugcaaagca agauaaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  654
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  654
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagccaa cgcgaucacc accauccuaa cggcagucac cuucugcuuc      240

gcaucaggcc aaaacaucac agaagaguuc uaccaaagca caugcuccgc cguauccaaa      300

ggcuaccuca gcgcccuacg cacaggcugg uacacaucug ucaucaccau agaacucucc      360

aacaucaaag aaaacaaaug caacggcacu gacgccaaag uaaagcugau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuccaacuac ucaugcaauc caccccugca      480

accaacaaca gggcccgccg cgaacucccc cgcuucauga acuacacuuu aaacaacgcc      540

aaaaagacca acgucacacu cagcaagaaa cggaaacgac gauuccuagg guuucuccua      600

ggcgucggcu cggcaaucgc cuccggcguc gccguaagca aaguacuaca ccuagaaggc      660

gaagugaaca aaaucaaaag ugcccuucuc uccaccaaca aggccguagu cucucuaucc      720

aacggagucu caguccucac cucaaagguc cucgaccuca aaaacuacau cgacaaacaa      780

cuacucccca uugucaacaa gcagucaugc uccauaucaa acaucgaaac cgucaucgag      840

uuccaacaga aaaacaaccg acuccucgaa auaaccagag aguucucggu caacgccggc      900

gucaccaccc cagucagcac cuacaugcuc acuaacuccg aacuccuauc ccucaucaac      960

gacaugccaa uuaccaacga ccaaaagaaa cuaaugucga acaacguuca aaucguccga     1020

caacaaaguu acuccaucau gagcauaauc aaagaagaag uucuagcgua cgucguccaa     1080

cucccacuau acggcgucau cgacacuccg ugcuggaaac uccacacauc accccuaugu     1140

acaaccaaca caaaagaagg cagcaacauc ugccucaccc gcaccgaccg agggugguau     1200

ugcgauaacg cuggcagcgu cuccuucuuc ccccaagccg aaaccugcaa aguccaauca     1260

aacagaguau ucugcgacac caugaacucc cuuacucucc cuagcgaagu caaccucugc     1320

aacguugaca uauucaaccc caaauacgac ugcaaaauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucacauc ucuaggugcc auugucuccu gcuacggaaa aaccaaaugc     1440

acagccucca acaaaaaccg cggcaucaua aaaaccuucu ccaacggcug cgacuacguc     1500

aguaauaaag gcgucgacac gguauccguu gggaauacgc uuuacuacgu aaauaaacaa     1560

gaaggcaaau cccucuacgu caaaggugaa cccaucauaa acuucuacga cccgcuugug     1620

uucccauccg acgaguucga cgccagcauc agccagguca acgaaaagau caaccaaucc     1680

cuagccuuca uccgcaaaag cgacgaacua cuacacaacg ucaacgccgg aaaauccaca     1740

accaacauca ugaucaccac caucaucauc gucaucaucg uaauccuacu cucucucauc     1800

gccgucggcc uccuacugua cuguaaagcc cgauagggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  655
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  655
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagauaag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  656
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  656
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  657
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  657
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  658
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  658
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  659
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  659
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  660
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  660
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  661
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  661
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  662
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  662
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uacucaaagc caacgcaaua acaacaauac      120

uaacagcagu aacauucugc uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa      180

guacaugcag ugcagucucu aaaggauacc ucagugccuu acgcacagga ugguacacau      240

caguaauaac aaucgaacuu ucaaacauaa aagaaaacaa augcaaugga accgacgcca      300

aaguaaaacu aaucaaacaa gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac      360

uccuaaugca auccacacca gcaacaaaua acagagcaag acgagaacuc ccucgauuca      420

ugaauuacac auuaaacaac gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac      480

guagauuucu aggauuccua cuaggcguag gguccgccau ugcaucagga guagcaguua      540

gcaaaguauu acauuuagaa ggagaaguaa auaaaaucaa aagcgcacua cucucaacca      600

acaaagcagu aguaucacuc ucaaacggag uaucaguacu aacauccaaa guacucgacc      660

ucaaaaacua cauagacaaa caauuacuac ccauaguaaa caaacaauca ugcucuauau      720

caaauaucga aacaguaauc gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa      780

gagaguucuc cgucaaugcc ggagucacca caccagucuc aacauacaug cuaaccaacu      840

cugaacuccu aucacuaaua aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu      900

caaauaacgu acaaauagua cgacaacaaa guuauuccau aaugaguaua aucaaagaag      960

aaguguuagc auacguaguc caacuaccau uauauggagu aauagacaca ccauguugga     1020

aauuacacac cucaccacuc ugcacuacca auacaaaaga aggcucaaau auaugccuaa     1080

cucgcacaga cagaggcugg uacugcgaua acgcaggauc cguaucuuuc uuuccccaag     1140

cagaaacuug caaaguacaa ucaaacagag ucuucugcga caccaugaau agucucacau     1200

uaccaucuga aguaaaccua uguaacguag auauauucaa uccaaaauac gacugcaaaa     1260

uaaugacauc aaaaaccgac gucucuagca guguaaucac aucacuagga gcaauaguaa     1320

gcugcuaugg aaaaacaaaa uguacagcau caaacaaaaa caggggaaua auaaaaaccu     1380

ucucaaacgg augugacuac guaucaaaua aaggcguaga cacaguaagc guaggaaaca     1440

cccuauacua cguuaacaaa caagaaggga aaucauuaua cguaaaagga gaaccaauaa     1500

uaaacuucua cgauccacuc guauucccau ccgacgaauu ugacgccagc auaucccaag     1560

uuaacgaaaa aauaaaccaa ucacuugcau uuauacgaaa aucugaugaa cuucuccaca     1620

acguaaaugc aggaaaaucc accaccaaua uaaugaucac aacuaucauc auaguaauaa     1680

ucgucauuuu acuaucauua auagcaguug gccuacuucu auacugcaaa gcaagauaag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  663
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  663
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc caacgcgauc accaccaucc      120

uaacggcagu caccuucugc uucgcaucag gccaaaacau cacagaagag uucuaccaaa      180

gcacaugcuc cgccguaucc aaaggcuacc ucagcgcccu acgcacaggc ugguacacau      240

cugucaucac cauagaacuc uccaacauca aagaaaacaa augcaacggc acugacgcca      300

aaguaaagcu gaucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuccaac      360

uacucaugca auccaccccu gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca      420

ugaacuacac uuuaaacaac gccaaaaaga ccaacgucac acucagcaag aaacggaaac      480

gacgauuccu aggguuucuc cuaggcgucg gcucggcaau cgccuccggc gucgccguaa      540

gcaaaguacu acaccuagaa ggcgaaguga acaaaaucaa aagugcccuu cucuccacca      600

acaaggccgu agucucucua uccaacggag ucucaguccu caccucaaag guccucgacc      660

ucaaaaacua caucgacaaa caacuacucc ccauugucaa caagcaguca ugcuccauau      720

caaacaucga aaccgucauc gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca      780

gagaguucuc ggucaacgcc ggcgucacca ccccagucag caccuacaug cucacuaacu      840

ccgaacuccu aucccucauc aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu      900

cgaacaacgu ucaaaucguc cgacaacaaa guuacuccau caugagcaua aucaaagaag      960

aaguucuagc guacgucguc caacucccac uauacggcgu caucgacacu ccgugcugga     1020

aacuccacac aucaccccua uguacaacca acacaaaaga aggcagcaac aucugccuca     1080

cccgcaccga ccgagggugg uauugcgaua acgcuggcag cgucuccuuc uucccccaag     1140

ccgaaaccug caaaguccaa ucaaacagag uauucugcga caccaugaac ucccuuacuc     1200

ucccuagcga agucaaccuc ugcaacguug acauauucaa ccccaaauac gacugcaaaa     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac aucucuaggu gccauugucu     1320

ccugcuacgg aaaaaccaaa ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu     1380

ucuccaacgg cugcgacuac gucaguaaua aaggcgucga cacgguaucc guugggaaua     1440

cgcuuuacua cguaaauaaa caagaaggca aaucccucua cgucaaaggu gaacccauca     1500

uaaacuucua cgacccgcuu guguucccau ccgacgaguu cgacgccagc aucagccagg     1560

ucaacgaaaa gaucaaccaa ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca     1620

acgucaacgc cggaaaaucc acaaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucguaauccu acucucucuc aucgccgucg gccuccuacu guacuguaaa gcccgauagg     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  664
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  664
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agauaaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  665
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  665
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  666
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  666
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  667
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  667
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  668
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  668
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  669
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  669
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  670
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  670
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cggugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  671
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  671
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaauac ucaaagccaa cgcaauaaca acaauacuaa cagcaguaac auucugcuuc      240

gcaucaggac aaaacaucac agaagaauuu uaccaaagua caugcagugc agucucuaaa      300

ggauaccuca gugccuuacg cacaggaugg uacacaucag uaauaacaau cgaacuuuca      360

aacauaaaag aaaacaaaug caauggaacc gacgccaaag uaaaacuaau caaacaagaa      420

cuagacaaau auaaaaaugc aguaacagaa uuacaacucc uaaugcaauc cacaccagca      480

acaaauaaca gagcaagacg agaacucccu cgauucauga auuacacauu aaacaacgca      540

aaaaaaacua acguaacuuu aucaaaaaaa agaaaacgua gauuucuagg auuccuacua      600

ggcguagggu ccgccauugc aucaggagua gcaguuagca aaguauuaca uuuagaagga      660

gaaguaaaua aaaucaaaag cgcacuacuc ucaaccaaca aagcaguagu aucacucuca      720

aacggaguau caguacuaac auccaaagua cucgaccuca aaaacuacau agacaaacaa      780

uuacuaccca uaguaaacaa acaaucaugc ucuauaucaa auaucgaaac aguaaucgaa      840

uuucaacaaa aaaacaaucg acuacuugaa auaacaagag aguucuccgu caaugccgga      900

gucaccacac cagucucaac auacaugcua accaacucug aacuccuauc acuaauaaau      960

gacaugccaa uaacaaacga ccaaaaaaaa cuaaugucaa auaacguaca aauaguacga     1020

caacaaaguu auuccauaau gaguauaauc aaagaagaag uguuagcaua cguaguccaa     1080

cuaccauuau auggaguaau agacacacca uguuggaaau uacacaccuc accacucugc     1140

acuaccaaua caaaagaagg cucaaauaua ugccuaacuc gcacagacag aggcugguac     1200

ugcgauaacg caggauccgu aucuuucuuu ccccaagcag aaacuugcaa aguacaauca     1260

aacagagucu ucugcgacac caugaauagu cucacauuac caucugaagu aaaccuaugu     1320

aacguagaua uauucaaucc aaaauacgac ugcaaaauaa ugacaucaaa aaccgacguc     1380

ucuagcagug uaaucacauc acuaggagca auaguaagcu gcuauggaaa aacaaaaugu     1440

acagcaucaa acaaaaacag gggaauaaua aaaaccuucu caaacggaug ugacuacgua     1500

ucaaauaaag gcguagacac aguaagcgua ggaaacaccc uauacuacgu uaacaaacaa     1560

gaagggaaau cauuauacgu aaaaggagaa ccaauaauaa acuucuacga uccacucgua     1620

uucccauccg acgaauuuga cgccagcaua ucccaaguua acgaaaaaau aaaccaauca     1680

cuugcauuua uacgaaaauc ugaugaacuu cuccacaacg uaaaugcagg aaaauccacc     1740

accaauauaa ugaucacaac uaucaucaua guaauaaucg ucauuuuacu aucauuaaua     1800

gcaguuggcc uacuucuaua cugcaaagca agauaaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  672
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  672
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagccaa cgcgaucacc accauccuaa cggcagucac cuucugcuuc      240

gcaucaggcc aaaacaucac agaagaguuc uaccaaagca caugcuccgc cguauccaaa      300

ggcuaccuca gcgcccuacg cacaggcugg uacacaucug ucaucaccau agaacucucc      360

aacaucaaag aaaacaaaug caacggcacu gacgccaaag uaaagcugau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuccaacuac ucaugcaauc caccccugca      480

accaacaaca gggcccgccg cgaacucccc cgcuucauga acuacacuuu aaacaacgcc      540

aaaaagacca acgucacacu cagcaagaaa cggaaacgac gauuccuagg guuucuccua      600

ggcgucggcu cggcaaucgc cuccggcguc gccguaagca aaguacuaca ccuagaaggc      660

gaagugaaca aaaucaaaag ugcccuucuc uccaccaaca aggccguagu cucucuaucc      720

aacggagucu caguccucac cucaaagguc cucgaccuca aaaacuacau cgacaaacaa      780

cuacucccca uugucaacaa gcagucaugc uccauaucaa acaucgaaac cgucaucgag      840

uuccaacaga aaaacaaccg acuccucgaa auaaccagag aguucucggu caacgccggc      900

gucaccaccc cagucagcac cuacaugcuc acuaacuccg aacuccuauc ccucaucaac      960

gacaugccaa uuaccaacga ccaaaagaaa cuaaugucga acaacguuca aaucguccga     1020

caacaaaguu acuccaucau gagcauaauc aaagaagaag uucuagcgua cgucguccaa     1080

cucccacuau acggcgucau cgacacuccg ugcuggaaac uccacacauc accccuaugu     1140

acaaccaaca caaaagaagg cagcaacauc ugccucaccc gcaccgaccg agggugguau     1200

ugcgauaacg cuggcagcgu cuccuucuuc ccccaagccg aaaccugcaa aguccaauca     1260

aacagaguau ucugcgacac caugaacucc cuuacucucc cuagcgaagu caaccucugc     1320

aacguugaca uauucaaccc caaauacgac ugcaaaauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucacauc ucuaggugcc auugucuccu gcuacggaaa aaccaaaugc     1440

acagccucca acaaaaaccg cggcaucaua aaaaccuucu ccaacggcug cgacuacguc     1500

aguaauaaag gcgucgacac gguauccguu gggaauacgc uuuacuacgu aaauaaacaa     1560

gaaggcaaau cccucuacgu caaaggugaa cccaucauaa acuucuacga cccgcuugug     1620

uucccauccg acgaguucga cgccagcauc agccagguca acgaaaagau caaccaaucc     1680

cuagccuuca uccgcaaaag cgacgaacua cuacacaacg ucaacgccgg aaaauccaca     1740

accaacauca ugaucaccac caucaucauc gucaucaucg uaauccuacu cucucucauc     1800

gccgucggcc uccuacugua cuguaaagcc cgauagggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  673
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  673
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      180

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      240

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      300

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      360

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      420

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      480

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      540

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      600

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      660

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      720

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      780

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      840

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc      900

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu      960

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua     1020

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1080

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1140

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1200

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1260

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1320

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1380

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1440

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1500

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1560

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1620

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1680

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1740

auugcuguug gacugcucuu auacuguaag gccagauaag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  674
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  674
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      540

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      600

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      660

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      780

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      840

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      900

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      960

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc     1020

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1080

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1140

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1200

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1380

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1500

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1560

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1680

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1740

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  675
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  675
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      540

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      600

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      660

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      780

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      840

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      960

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc     1020

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1080

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1140

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1200

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1260

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1380

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1500

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1560

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1620

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1680

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1740

aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  676
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  676
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      480

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      540

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      600

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      660

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      720

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      780

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      840

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      960

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc     1020

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1080

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1140

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1200

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1380

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1440

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1500

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1560

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1620

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1680

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1740

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  677
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  677
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      480

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      540

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      600

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      660

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      720

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      780

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      840

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc      900

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug      960

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu     1020

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1080

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1140

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1200

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1260

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1320

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1380

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1440

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1500

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1560

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1620

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1680

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1740

aucgcugugg gccugcuucu guacugcaag gccaggugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  678
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  678
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      480

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      540

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      600

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      660

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      720

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      780

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      840

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      960

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug     1020

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1080

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1140

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1200

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1260

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1320

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1380

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1500

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1560

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1680

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1740

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  679
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  679
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      480

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      540

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      600

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      660

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      720

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      780

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      840

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc      900

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu      960

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug     1020

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1080

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1140

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1200

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1260

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1320

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1380

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1440

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1500

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1560

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1620

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1680

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1740

aucgcggugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  680
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  680
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaauuacuaa uacucaaagc caacgcaaua acaacaauac uaacagcagu aacauucugc      180

uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa guacaugcag ugcagucucu      240

aaaggauacc ucagugccuu acgcacagga ugguacacau caguaauaac aaucgaacuu      300

ucaaacauaa aagaaaacaa augcaaugga accgacgcca aaguaaaacu aaucaaacaa      360

gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac uccuaaugca auccacacca      420

gcaacaaaua acagagcaag acgagaacuc ccucgauuca ugaauuacac auuaaacaac      480

gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac guagauuucu aggauuccua      540

cuaggcguag gguccgccau ugcaucagga guagcaguua gcaaaguauu acauuuagaa      600

ggagaaguaa auaaaaucaa aagcgcacua cucucaacca acaaagcagu aguaucacuc      660

ucaaacggag uaucaguacu aacauccaaa guacucgacc ucaaaaacua cauagacaaa      720

caauuacuac ccauaguaaa caaacaauca ugcucuauau caaauaucga aacaguaauc      780

gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa gagaguucuc cgucaaugcc      840

ggagucacca caccagucuc aacauacaug cuaaccaacu cugaacuccu aucacuaaua      900

aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu acaaauagua      960

cgacaacaaa guuauuccau aaugaguaua aucaaagaag aaguguuagc auacguaguc     1020

caacuaccau uauauggagu aauagacaca ccauguugga aauuacacac cucaccacuc     1080

ugcacuacca auacaaaaga aggcucaaau auaugccuaa cucgcacaga cagaggcugg     1140

uacugcgaua acgcaggauc cguaucuuuc uuuccccaag cagaaacuug caaaguacaa     1200

ucaaacagag ucuucugcga caccaugaau agucucacau uaccaucuga aguaaaccua     1260

uguaacguag auauauucaa uccaaaauac gacugcaaaa uaaugacauc aaaaaccgac     1320

gucucuagca guguaaucac aucacuagga gcaauaguaa gcugcuaugg aaaaacaaaa     1380

uguacagcau caaacaaaaa caggggaaua auaaaaaccu ucucaaacgg augugacuac     1440

guaucaaaua aaggcguaga cacaguaagc guaggaaaca cccuauacua cguuaacaaa     1500

caagaaggga aaucauuaua cguaaaagga gaaccaauaa uaaacuucua cgauccacuc     1560

guauucccau ccgacgaauu ugacgccagc auaucccaag uuaacgaaaa aauaaaccaa     1620

ucacuugcau uuauacgaaa aucugaugaa cuucuccaca acguaaaugc aggaaaaucc     1680

accaccaaua uaaugaucac aacuaucauc auaguaauaa ucgucauuuu acuaucauua     1740

auagcaguug gccuacuucu auacugcaaa gcaagauaag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  681
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  681
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuaa uccuaaaagc caacgcgauc accaccaucc uaacggcagu caccuucugc      180

uucgcaucag gccaaaacau cacagaagag uucuaccaaa gcacaugcuc cgccguaucc      240

aaaggcuacc ucagcgcccu acgcacaggc ugguacacau cugucaucac cauagaacuc      300

uccaacauca aagaaaacaa augcaacggc acugacgcca aaguaaagcu gaucaaacaa      360

gaacucgaca aauacaaaaa cgcagucacc gaacuccaac uacucaugca auccaccccu      420

gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca ugaacuacac uuuaaacaac      480

gccaaaaaga ccaacgucac acucagcaag aaacggaaac gacgauuccu aggguuucuc      540

cuaggcgucg gcucggcaau cgccuccggc gucgccguaa gcaaaguacu acaccuagaa      600

ggcgaaguga acaaaaucaa aagugcccuu cucuccacca acaaggccgu agucucucua      660

uccaacggag ucucaguccu caccucaaag guccucgacc ucaaaaacua caucgacaaa      720

caacuacucc ccauugucaa caagcaguca ugcuccauau caaacaucga aaccgucauc      780

gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca gagaguucuc ggucaacgcc      840

ggcgucacca ccccagucag caccuacaug cucacuaacu ccgaacuccu aucccucauc      900

aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu cgaacaacgu ucaaaucguc      960

cgacaacaaa guuacuccau caugagcaua aucaaagaag aaguucuagc guacgucguc     1020

caacucccac uauacggcgu caucgacacu ccgugcugga aacuccacac aucaccccua     1080

uguacaacca acacaaaaga aggcagcaac aucugccuca cccgcaccga ccgagggugg     1140

uauugcgaua acgcuggcag cgucuccuuc uucccccaag ccgaaaccug caaaguccaa     1200

ucaaacagag uauucugcga caccaugaac ucccuuacuc ucccuagcga agucaaccuc     1260

ugcaacguug acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1320

gucuccuccu ccgucaucac aucucuaggu gccauugucu ccugcuacgg aaaaaccaaa     1380

ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu ucuccaacgg cugcgacuac     1440

gucaguaaua aaggcgucga cacgguaucc guugggaaua cgcuuuacua cguaaauaaa     1500

caagaaggca aaucccucua cgucaaaggu gaacccauca uaaacuucua cgacccgcuu     1560

guguucccau ccgacgaguu cgacgccagc aucagccagg ucaacgaaaa gaucaaccaa     1620

ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca acgucaacgc cggaaaaucc     1680

acaaccaaca ucaugaucac caccaucauc aucgucauca ucguaauccu acucucucuc     1740

aucgccgucg gccuccuacu guacuguaaa gcccgauagg gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  682
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  682
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  683
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  683
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  684
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  684
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  685
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  685
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  686
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  686
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccaggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  687
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  687
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  688
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  688
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  689
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  689
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauacucaaa      120

gccaacgcaa uaacaacaau acuaacagca guaacauucu gcuucgcauc aggacaaaac      180

aucacagaag aauuuuacca aaguacaugc agugcagucu cuaaaggaua ccucagugcc      240

uuacgcacag gaugguacac aucaguaaua acaaucgaac uuucaaacau aaaagaaaac      300

aaaugcaaug gaaccgacgc caaaguaaaa cuaaucaaac aagaacuaga caaauauaaa      360

aaugcaguaa cagaauuaca acuccuaaug caauccacac cagcaacaaa uaacagagca      420

agacgagaac ucccucgauu caugaauuac acauuaaaca acgcaaaaaa aacuaacgua      480

acuuuaucaa aaaaaagaaa acguagauuu cuaggauucc uacuaggcgu aggguccgcc      540

auugcaucag gaguagcagu uagcaaagua uuacauuuag aaggagaagu aaauaaaauc      600

aaaagcgcac uacucucaac caacaaagca guaguaucac ucucaaacgg aguaucagua      660

cuaacaucca aaguacucga ccucaaaaac uacauagaca aacaauuacu acccauagua      720

aacaaacaau caugcucuau aucaaauauc gaaacaguaa ucgaauuuca acaaaaaaac      780

aaucgacuac uugaaauaac aagagaguuc uccgucaaug ccggagucac cacaccaguc      840

ucaacauaca ugcuaaccaa cucugaacuc cuaucacuaa uaaaugacau gccaauaaca      900

aacgaccaaa aaaaacuaau gucaaauaac guacaaauag uacgacaaca aaguuauucc      960

auaaugagua uaaucaaaga agaaguguua gcauacguag uccaacuacc auuauaugga     1020

guaauagaca caccauguug gaaauuacac accucaccac ucugcacuac caauacaaaa     1080

gaaggcucaa auauaugccu aacucgcaca gacagaggcu gguacugcga uaacgcagga     1140

uccguaucuu ucuuucccca agcagaaacu ugcaaaguac aaucaaacag agucuucugc     1200

gacaccauga auagucucac auuaccaucu gaaguaaacc uauguaacgu agauauauuc     1260

aauccaaaau acgacugcaa aauaaugaca ucaaaaaccg acgucucuag caguguaauc     1320

acaucacuag gagcaauagu aagcugcuau ggaaaaacaa aauguacagc aucaaacaaa     1380

aacaggggaa uaauaaaaac cuucucaaac ggaugugacu acguaucaaa uaaaggcgua     1440

gacacaguaa gcguaggaaa cacccuauac uacguuaaca aacaagaagg gaaaucauua     1500

uacguaaaag gagaaccaau aauaaacuuc uacgauccac ucguauuccc auccgacgaa     1560

uuugacgcca gcauauccca aguuaacgaa aaaauaaacc aaucacuugc auuuauacga     1620

aaaucugaug aacuucucca caacguaaau gcaggaaaau ccaccaccaa uauaaugauc     1680

acaacuauca ucauaguaau aaucgucauu uuacuaucau uaauagcagu uggccuacuu     1740

cuauacugca aagcaagaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  690
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  690
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gccaacgcga ucaccaccau ccuaacggca gucaccuucu gcuucgcauc aggccaaaac      180

aucacagaag aguucuacca aagcacaugc uccgccguau ccaaaggcua ccucagcgcc      240

cuacgcacag gcugguacac aucugucauc accauagaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacugacgc caaaguaaag cugaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacucca acuacucaug caauccaccc cugcaaccaa caacagggcc      420

cgccgcgaac ucccccgcuu caugaacuac acuuuaaaca acgccaaaaa gaccaacguc      480

acacucagca agaaacggaa acgacgauuc cuaggguuuc uccuaggcgu cggcucggca      540

aucgccuccg gcgucgccgu aagcaaagua cuacaccuag aaggcgaagu gaacaaaauc      600

aaaagugccc uucucuccac caacaaggcc guagucucuc uauccaacgg agucucaguc      660

cucaccucaa agguccucga ccucaaaaac uacaucgaca aacaacuacu ccccauuguc      720

aacaagcagu caugcuccau aucaaacauc gaaaccguca ucgaguucca acagaaaaac      780

aaccgacucc ucgaaauaac cagagaguuc ucggucaacg ccggcgucac caccccaguc      840

agcaccuaca ugcucacuaa cuccgaacuc cuaucccuca ucaacgacau gccaauuacc      900

aacgaccaaa agaaacuaau gucgaacaac guucaaaucg uccgacaaca aaguuacucc      960

aucaugagca uaaucaaaga agaaguucua gcguacgucg uccaacuccc acuauacggc     1020

gucaucgaca cuccgugcug gaaacuccac acaucacccc uauguacaac caacacaaaa     1080

gaaggcagca acaucugccu cacccgcacc gaccgagggu gguauugcga uaacgcuggc     1140

agcgucuccu ucuuccccca agccgaaacc ugcaaagucc aaucaaacag aguauucugc     1200

gacaccauga acucccuuac ucucccuagc gaagucaacc ucugcaacgu ugacauauuc     1260

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

acaucucuag gugccauugu cuccugcuac ggaaaaacca aaugcacagc cuccaacaaa     1380

aaccgcggca ucauaaaaac cuucuccaac ggcugcgacu acgucaguaa uaaaggcguc     1440

gacacgguau ccguugggaa uacgcuuuac uacguaaaua aacaagaagg caaaucccuc     1500

uacgucaaag gugaacccau cauaaacuuc uacgacccgc uuguguuccc auccgacgag     1560

uucgacgcca gcaucagcca ggucaacgaa aagaucaacc aaucccuagc cuucauccgc     1620

aaaagcgacg aacuacuaca caacgucaac gccggaaaau ccacaaccaa caucaugauc     1680

accaccauca ucaucgucau caucguaauc cuacucucuc ucaucgccgu cggccuccua     1740

cuguacugua aagcccgaua gggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  691
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  691
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  692
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  692
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  693
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  693
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  694
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  694
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  695
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  695
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccaggug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  696
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  696
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  697
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  697
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccggug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  698
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  698
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauacucaaa gccaacgcaa uaacaacaau acuaacagca      120

guaacauucu gcuucgcauc aggacaaaac aucacagaag aauuuuacca aaguacaugc      180

agugcagucu cuaaaggaua ccucagugcc uuacgcacag gaugguacac aucaguaaua      240

acaaucgaac uuucaaacau aaaagaaaac aaaugcaaug gaaccgacgc caaaguaaaa      300

cuaaucaaac aagaacuaga caaauauaaa aaugcaguaa cagaauuaca acuccuaaug      360

caauccacac cagcaacaaa uaacagagca agacgagaac ucccucgauu caugaauuac      420

acauuaaaca acgcaaaaaa aacuaacgua acuuuaucaa aaaaaagaaa acguagauuu      480

cuaggauucc uacuaggcgu aggguccgcc auugcaucag gaguagcagu uagcaaagua      540

uuacauuuag aaggagaagu aaauaaaauc aaaagcgcac uacucucaac caacaaagca      600

guaguaucac ucucaaacgg aguaucagua cuaacaucca aaguacucga ccucaaaaac      660

uacauagaca aacaauuacu acccauagua aacaaacaau caugcucuau aucaaauauc      720

gaaacaguaa ucgaauuuca acaaaaaaac aaucgacuac uugaaauaac aagagaguuc      780

uccgucaaug ccggagucac cacaccaguc ucaacauaca ugcuaaccaa cucugaacuc      840

cuaucacuaa uaaaugacau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      900

guacaaauag uacgacaaca aaguuauucc auaaugagua uaaucaaaga agaaguguua      960

gcauacguag uccaacuacc auuauaugga guaauagaca caccauguug gaaauuacac     1020

accucaccac ucugcacuac caauacaaaa gaaggcucaa auauaugccu aacucgcaca     1080

gacagaggcu gguacugcga uaacgcagga uccguaucuu ucuuucccca agcagaaacu     1140

ugcaaaguac aaucaaacag agucuucugc gacaccauga auagucucac auuaccaucu     1200

gaaguaaacc uauguaacgu agauauauuc aauccaaaau acgacugcaa aauaaugaca     1260

ucaaaaaccg acgucucuag caguguaauc acaucacuag gagcaauagu aagcugcuau     1320

ggaaaaacaa aauguacagc aucaaacaaa aacaggggaa uaauaaaaac cuucucaaac     1380

ggaugugacu acguaucaaa uaaaggcgua gacacaguaa gcguaggaaa cacccuauac     1440

uacguuaaca aacaagaagg gaaaucauua uacguaaaag gagaaccaau aauaaacuuc     1500

uacgauccac ucguauuccc auccgacgaa uuugacgcca gcauauccca aguuaacgaa     1560

aaaauaaacc aaucacuugc auuuauacga aaaucugaug aacuucucca caacguaaau     1620

gcaggaaaau ccaccaccaa uauaaugauc acaacuauca ucauaguaau aaucgucauu     1680

uuacuaucau uaauagcagu uggccuacuu cuauacugca aagcaagaua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  699
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  699
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gccaacgcga ucaccaccau ccuaacggca      120

gucaccuucu gcuucgcauc aggccaaaac aucacagaag aguucuacca aagcacaugc      180

uccgccguau ccaaaggcua ccucagcgcc cuacgcacag gcugguacac aucugucauc      240

accauagaac ucuccaacau caaagaaaac aaaugcaacg gcacugacgc caaaguaaag      300

cugaucaaac aagaacucga caaauacaaa aacgcaguca ccgaacucca acuacucaug      360

caauccaccc cugcaaccaa caacagggcc cgccgcgaac ucccccgcuu caugaacuac      420

acuuuaaaca acgccaaaaa gaccaacguc acacucagca agaaacggaa acgacgauuc      480

cuaggguuuc uccuaggcgu cggcucggca aucgccuccg gcgucgccgu aagcaaagua      540

cuacaccuag aaggcgaagu gaacaaaauc aaaagugccc uucucuccac caacaaggcc      600

guagucucuc uauccaacgg agucucaguc cucaccucaa agguccucga ccucaaaaac      660

uacaucgaca aacaacuacu ccccauuguc aacaagcagu caugcuccau aucaaacauc      720

gaaaccguca ucgaguucca acagaaaaac aaccgacucc ucgaaauaac cagagaguuc      780

ucggucaacg ccggcgucac caccccaguc agcaccuaca ugcucacuaa cuccgaacuc      840

cuaucccuca ucaacgacau gccaauuacc aacgaccaaa agaaacuaau gucgaacaac      900

guucaaaucg uccgacaaca aaguuacucc aucaugagca uaaucaaaga agaaguucua      960

gcguacgucg uccaacuccc acuauacggc gucaucgaca cuccgugcug gaaacuccac     1020

acaucacccc uauguacaac caacacaaaa gaaggcagca acaucugccu cacccgcacc     1080

gaccgagggu gguauugcga uaacgcuggc agcgucuccu ucuuccccca agccgaaacc     1140

ugcaaagucc aaucaaacag aguauucugc gacaccauga acucccuuac ucucccuagc     1200

gaagucaacc ucugcaacgu ugacauauuc aaccccaaau acgacugcaa aaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc acaucucuag gugccauugu cuccugcuac     1320

ggaaaaacca aaugcacagc cuccaacaaa aaccgcggca ucauaaaaac cuucuccaac     1380

ggcugcgacu acgucaguaa uaaaggcguc gacacgguau ccguugggaa uacgcuuuac     1440

uacguaaaua aacaagaagg caaaucccuc uacgucaaag gugaacccau cauaaacuuc     1500

uacgacccgc uuguguuccc auccgacgag uucgacgcca gcaucagcca ggucaacgaa     1560

aagaucaacc aaucccuagc cuucauccgc aaaagcgacg aacuacuaca caacgucaac     1620

gccggaaaau ccacaaccaa caucaugauc accaccauca ucaucgucau caucguaauc     1680

cuacucucuc ucaucgccgu cggccuccua cuguacugua aagcccgaua gggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  700
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  700
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gauaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  701
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  701
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  702
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  702
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  703
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  703
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  704
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  704
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  705
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  705
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  706
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  706
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  707
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  707
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauacu caaagccaac gcaauaacaa caauacuaac agcaguaaca      180

uucugcuucg caucaggaca aaacaucaca gaagaauuuu accaaaguac augcagugca      240

gucucuaaag gauaccucag ugccuuacgc acaggauggu acacaucagu aauaacaauc      300

gaacuuucaa acauaaaaga aaacaaaugc aauggaaccg acgccaaagu aaaacuaauc      360

aaacaagaac uagacaaaua uaaaaaugca guaacagaau uacaacuccu aaugcaaucc      420

acaccagcaa caaauaacag agcaagacga gaacucccuc gauucaugaa uuacacauua      480

aacaacgcaa aaaaaacuaa cguaacuuua ucaaaaaaaa gaaaacguag auuucuagga      540

uuccuacuag gcguaggguc cgccauugca ucaggaguag caguuagcaa aguauuacau      600

uuagaaggag aaguaaauaa aaucaaaagc gcacuacucu caaccaacaa agcaguagua      660

ucacucucaa acggaguauc aguacuaaca uccaaaguac ucgaccucaa aaacuacaua      720

gacaaacaau uacuacccau aguaaacaaa caaucaugcu cuauaucaaa uaucgaaaca      780

guaaucgaau uucaacaaaa aaacaaucga cuacuugaaa uaacaagaga guucuccguc      840

aaugccggag ucaccacacc agucucaaca uacaugcuaa ccaacucuga acuccuauca      900

cuaauaaaug acaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      960

auaguacgac aacaaaguua uuccauaaug aguauaauca aagaagaagu guuagcauac     1020

guaguccaac uaccauuaua uggaguaaua gacacaccau guuggaaauu acacaccuca     1080

ccacucugca cuaccaauac aaaagaaggc ucaaauauau gccuaacucg cacagacaga     1140

ggcugguacu gcgauaacgc aggauccgua ucuuucuuuc cccaagcaga aacuugcaaa     1200

guacaaucaa acagagucuu cugcgacacc augaauaguc ucacauuacc aucugaagua     1260

aaccuaugua acguagauau auucaaucca aaauacgacu gcaaaauaau gacaucaaaa     1320

accgacgucu cuagcagugu aaucacauca cuaggagcaa uaguaagcug cuauggaaaa     1380

acaaaaugua cagcaucaaa caaaaacagg ggaauaauaa aaaccuucuc aaacggaugu     1440

gacuacguau caaauaaagg cguagacaca guaagcguag gaaacacccu auacuacguu     1500

aacaaacaag aagggaaauc auuauacgua aaaggagaac caauaauaaa cuucuacgau     1560

ccacucguau ucccauccga cgaauuugac gccagcauau cccaaguuaa cgaaaaaaua     1620

aaccaaucac uugcauuuau acgaaaaucu gaugaacuuc uccacaacgu aaaugcagga     1680

aaauccacca ccaauauaau gaucacaacu aucaucauag uaauaaucgu cauuuuacua     1740

ucauuaauag caguuggccu acuucuauac ugcaaagcaa gauaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  708
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  708
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagccaac gcgaucacca ccauccuaac ggcagucacc      180

uucugcuucg caucaggcca aaacaucaca gaagaguucu accaaagcac augcuccgcc      240

guauccaaag gcuaccucag cgcccuacgc acaggcuggu acacaucugu caucaccaua      300

gaacucucca acaucaaaga aaacaaaugc aacggcacug acgccaaagu aaagcugauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uccaacuacu caugcaaucc      420

accccugcaa ccaacaacag ggcccgccgc gaacuccccc gcuucaugaa cuacacuuua      480

aacaacgcca aaaagaccaa cgucacacuc agcaagaaac ggaaacgacg auuccuaggg      540

uuucuccuag gcgucggcuc ggcaaucgcc uccggcgucg ccguaagcaa aguacuacac      600

cuagaaggcg aagugaacaa aaucaaaagu gcccuucucu ccaccaacaa ggccguaguc      660

ucucuaucca acggagucuc aguccucacc ucaaaggucc ucgaccucaa aaacuacauc      720

gacaaacaac uacuccccau ugucaacaag cagucaugcu ccauaucaaa caucgaaacc      780

gucaucgagu uccaacagaa aaacaaccga cuccucgaaa uaaccagaga guucucgguc      840

aacgccggcg ucaccacccc agucagcacc uacaugcuca cuaacuccga acuccuaucc      900

cucaucaacg acaugccaau uaccaacgac caaaagaaac uaaugucgaa caacguucaa      960

aucguccgac aacaaaguua cuccaucaug agcauaauca aagaagaagu ucuagcguac     1020

gucguccaac ucccacuaua cggcgucauc gacacuccgu gcuggaaacu ccacacauca     1080

ccccuaugua caaccaacac aaaagaaggc agcaacaucu gccucacccg caccgaccga     1140

gggugguauu gcgauaacgc uggcagcguc uccuucuucc cccaagccga aaccugcaaa     1200

guccaaucaa acagaguauu cugcgacacc augaacuccc uuacucuccc uagcgaaguc     1260

aaccucugca acguugacau auucaacccc aaauacgacu gcaaaaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucacaucu cuaggugcca uugucuccug cuacggaaaa     1380

accaaaugca cagccuccaa caaaaaccgc ggcaucauaa aaaccuucuc caacggcugc     1440

gacuacguca guaauaaagg cgucgacacg guauccguug ggaauacgcu uuacuacgua     1500

aauaaacaag aaggcaaauc ccucuacguc aaaggugaac ccaucauaaa cuucuacgac     1560

ccgcuugugu ucccauccga cgaguucgac gccagcauca gccaggucaa cgaaaagauc     1620

aaccaauccc uagccuucau ccgcaaaagc gacgaacuac uacacaacgu caacgccgga     1680

aaauccacaa ccaacaucau gaucaccacc aucaucaucg ucaucaucgu aauccuacuc     1740

ucucucaucg ccgucggccu ccuacuguac uguaaagccc gauagggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  709
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  709
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagau aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  710
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  710
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  711
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  711
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgcu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  712
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  712
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  713
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  713
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  714
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  714
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  715
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  715
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  716
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  716
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauacucaa agccaacgca      120

auaacaacaa uacuaacagc aguaacauuc ugcuucgcau caggacaaaa caucacagaa      180

gaauuuuacc aaaguacaug cagugcaguc ucuaaaggau accucagugc cuuacgcaca      240

ggaugguaca caucaguaau aacaaucgaa cuuucaaaca uaaaagaaaa caaaugcaau      300

ggaaccgacg ccaaaguaaa acuaaucaaa caagaacuag acaaauauaa aaaugcagua      360

acagaauuac aacuccuaau gcaauccaca ccagcaacaa auaacagagc aagacgagaa      420

cucccucgau ucaugaauua cacauuaaac aacgcaaaaa aaacuaacgu aacuuuauca      480

aaaaaaagaa aacguagauu ucuaggauuc cuacuaggcg uaggguccgc cauugcauca      540

ggaguagcag uuagcaaagu auuacauuua gaaggagaag uaaauaaaau caaaagcgca      600

cuacucucaa ccaacaaagc aguaguauca cucucaaacg gaguaucagu acuaacaucc      660

aaaguacucg accucaaaaa cuacauagac aaacaauuac uacccauagu aaacaaacaa      720

ucaugcucua uaucaaauau cgaaacagua aucgaauuuc aacaaaaaaa caaucgacua      780

cuugaaauaa caagagaguu cuccgucaau gccggaguca ccacaccagu cucaacauac      840

augcuaacca acucugaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa      900

aaaaaacuaa ugucaaauaa cguacaaaua guacgacaac aaaguuauuc cauaaugagu      960

auaaucaaag aagaaguguu agcauacgua guccaacuac cauuauaugg aguaauagac     1020

acaccauguu ggaaauuaca caccucacca cucugcacua ccaauacaaa agaaggcuca     1080

aauauaugcc uaacucgcac agacagaggc ugguacugcg auaacgcagg auccguaucu     1140

uucuuucccc aagcagaaac uugcaaagua caaucaaaca gagucuucug cgacaccaug     1200

aauagucuca cauuaccauc ugaaguaaac cuauguaacg uagauauauu caauccaaaa     1260

uacgacugca aaauaaugac aucaaaaacc gacgucucua gcaguguaau cacaucacua     1320

ggagcaauag uaagcugcua uggaaaaaca aaauguacag caucaaacaa aaacagggga     1380

auaauaaaaa ccuucucaaa cggaugugac uacguaucaa auaaaggcgu agacacagua     1440

agcguaggaa acacccuaua cuacguuaac aaacaagaag ggaaaucauu auacguaaaa     1500

ggagaaccaa uaauaaacuu cuacgaucca cucguauucc cauccgacga auuugacgcc     1560

agcauauccc aaguuaacga aaaaauaaac caaucacuug cauuuauacg aaaaucugau     1620

gaacuucucc acaacguaaa ugcaggaaaa uccaccacca auauaaugau cacaacuauc     1680

aucauaguaa uaaucgucau uuuacuauca uuaauagcag uuggccuacu ucuauacugc     1740

aaagcaagau aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  717
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  717
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agccaacgcg      120

aucaccacca uccuaacggc agucaccuuc ugcuucgcau caggccaaaa caucacagaa      180

gaguucuacc aaagcacaug cuccgccgua uccaaaggcu accucagcgc ccuacgcaca      240

ggcugguaca caucugucau caccauagaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacugacg ccaaaguaaa gcugaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacucc aacuacucau gcaauccacc ccugcaacca acaacagggc ccgccgcgaa      420

cucccccgcu ucaugaacua cacuuuaaac aacgccaaaa agaccaacgu cacacucagc      480

aagaaacgga aacgacgauu ccuaggguuu cuccuaggcg ucggcucggc aaucgccucc      540

ggcgucgccg uaagcaaagu acuacaccua gaaggcgaag ugaacaaaau caaaagugcc      600

cuucucucca ccaacaaggc cguagucucu cuauccaacg gagucucagu ccucaccuca      660

aagguccucg accucaaaaa cuacaucgac aaacaacuac uccccauugu caacaagcag      720

ucaugcucca uaucaaacau cgaaaccguc aucgaguucc aacagaaaaa caaccgacuc      780

cucgaaauaa ccagagaguu cucggucaac gccggcguca ccaccccagu cagcaccuac      840

augcucacua acuccgaacu ccuaucccuc aucaacgaca ugccaauuac caacgaccaa      900

aagaaacuaa ugucgaacaa cguucaaauc guccgacaac aaaguuacuc caucaugagc      960

auaaucaaag aagaaguucu agcguacguc guccaacucc cacuauacgg cgucaucgac     1020

acuccgugcu ggaaacucca cacaucaccc cuauguacaa ccaacacaaa agaaggcagc     1080

aacaucugcc ucacccgcac cgaccgaggg ugguauugcg auaacgcugg cagcgucucc     1140

uucuuccccc aagccgaaac cugcaaaguc caaucaaaca gaguauucug cgacaccaug     1200

aacucccuua cucucccuag cgaagucaac cucugcaacg uugacauauu caaccccaaa     1260

uacgacugca aaaucaugac cuccaagacc gacgucuccu ccuccgucau cacaucucua     1320

ggugccauug ucuccugcua cggaaaaacc aaaugcacag ccuccaacaa aaaccgcggc     1380

aucauaaaaa ccuucuccaa cggcugcgac uacgucagua auaaaggcgu cgacacggua     1440

uccguuggga auacgcuuua cuacguaaau aaacaagaag gcaaaucccu cuacgucaaa     1500

ggugaaccca ucauaaacuu cuacgacccg cuuguguucc cauccgacga guucgacgcc     1560

agcaucagcc aggucaacga aaagaucaac caaucccuag ccuucauccg caaaagcgac     1620

gaacuacuac acaacgucaa cgccggaaaa uccacaacca acaucaugau caccaccauc     1680

aucaucguca ucaucguaau ccuacucucu cucaucgccg ucggccuccu acuguacugu     1740

aaagcccgau agggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  718
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  718
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagau aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  719
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  719
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  720
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  720
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgcu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  721
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  721
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  722
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  722
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  723
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  723
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  724
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  724
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  725
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  725
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauacucaa agccaacgca      120

auaacaacaa uacuaacagc aguaacauuc ugcuucgcau caggacaaaa caucacagaa      180

gaauuuuacc aaaguacaug cagugcaguc ucuaaaggau accucagugc cuuacgcaca      240

ggaugguaca caucaguaau aacaaucgaa cuuucaaaca uaaaagaaaa caaaugcaau      300

ggaaccgacg ccaaaguaaa acuaaucaaa caagaacuag acaaauauaa aaaugcagua      360

acagaauuac aacuccuaau gcaauccaca ccagcaacaa auaacagagc aagacgagaa      420

cucccucgau ucaugaauua cacauuaaac aacgcaaaaa aaacuaacgu aacuuuauca      480

aaaaaaagaa aacguagauu ucuaggauuc cuacuaggcg uaggguccgc cauugcauca      540

ggaguagcag uuagcaaagu auuacauuua gaaggagaag uaaauaaaau caaaagcgca      600

cuacucucaa ccaacaaagc aguaguauca cucucaaacg gaguaucagu acuaacaucc      660

aaaguacucg accucaaaaa cuacauagac aaacaauuac uacccauagu aaacaaacaa      720

ucaugcucua uaucaaauau cgaaacagua aucgaauuuc aacaaaaaaa caaucgacua      780

cuugaaauaa caagagaguu cuccgucaau gccggaguca ccacaccagu cucaacauac      840

augcuaacca acucugaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa      900

aaaaaacuaa ugucaaauaa cguacaaaua guacgacaac aaaguuauuc cauaaugagu      960

auaaucaaag aagaaguguu agcauacgua guccaacuac cauuauaugg aguaauagac     1020

acaccauguu ggaaauuaca caccucacca cucugcacua ccaauacaaa agaaggcuca     1080

aauauaugcc uaacucgcac agacagaggc ugguacugcg auaacgcagg auccguaucu     1140

uucuuucccc aagcagaaac uugcaaagua caaucaaaca gagucuucug cgacaccaug     1200

aauagucuca cauuaccauc ugaaguaaac cuauguaacg uagauauauu caauccaaaa     1260

uacgacugca aaauaaugac aucaaaaacc gacgucucua gcaguguaau cacaucacua     1320

ggagcaauag uaagcugcua uggaaaaaca aaauguacag caucaaacaa aaacagggga     1380

auaauaaaaa ccuucucaaa cggaugugac uacguaucaa auaaaggcgu agacacagua     1440

agcguaggaa acacccuaua cuacguuaac aaacaagaag ggaaaucauu auacguaaaa     1500

ggagaaccaa uaauaaacuu cuacgaucca cucguauucc cauccgacga auuugacgcc     1560

agcauauccc aaguuaacga aaaaauaaac caaucacuug cauuuauacg aaaaucugau     1620

gaacuucucc acaacguaaa ugcaggaaaa uccaccacca auauaaugau cacaacuauc     1680

aucauaguaa uaaucgucau uuuacuauca uuaauagcag uuggccuacu ucuauacugc     1740

aaagcaagau aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  726
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  726
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agccaacgcg      120

aucaccacca uccuaacggc agucaccuuc ugcuucgcau caggccaaaa caucacagaa      180

gaguucuacc aaagcacaug cuccgccgua uccaaaggcu accucagcgc ccuacgcaca      240

ggcugguaca caucugucau caccauagaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacugacg ccaaaguaaa gcugaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacucc aacuacucau gcaauccacc ccugcaacca acaacagggc ccgccgcgaa      420

cucccccgcu ucaugaacua cacuuuaaac aacgccaaaa agaccaacgu cacacucagc      480

aagaaacgga aacgacgauu ccuaggguuu cuccuaggcg ucggcucggc aaucgccucc      540

ggcgucgccg uaagcaaagu acuacaccua gaaggcgaag ugaacaaaau caaaagugcc      600

cuucucucca ccaacaaggc cguagucucu cuauccaacg gagucucagu ccucaccuca      660

aagguccucg accucaaaaa cuacaucgac aaacaacuac uccccauugu caacaagcag      720

ucaugcucca uaucaaacau cgaaaccguc aucgaguucc aacagaaaaa caaccgacuc      780

cucgaaauaa ccagagaguu cucggucaac gccggcguca ccaccccagu cagcaccuac      840

augcucacua acuccgaacu ccuaucccuc aucaacgaca ugccaauuac caacgaccaa      900

aagaaacuaa ugucgaacaa cguucaaauc guccgacaac aaaguuacuc caucaugagc      960

auaaucaaag aagaaguucu agcguacguc guccaacucc cacuauacgg cgucaucgac     1020

acuccgugcu ggaaacucca cacaucaccc cuauguacaa ccaacacaaa agaaggcagc     1080

aacaucugcc ucacccgcac cgaccgaggg ugguauugcg auaacgcugg cagcgucucc     1140

uucuuccccc aagccgaaac cugcaaaguc caaucaaaca gaguauucug cgacaccaug     1200

aacucccuua cucucccuag cgaagucaac cucugcaacg uugacauauu caaccccaaa     1260

uacgacugca aaaucaugac cuccaagacc gacgucuccu ccuccgucau cacaucucua     1320

ggugccauug ucuccugcua cggaaaaacc aaaugcacag ccuccaacaa aaaccgcggc     1380

aucauaaaaa ccuucuccaa cggcugcgac uacgucagua auaaaggcgu cgacacggua     1440

uccguuggga auacgcuuua cuacguaaau aaacaagaag gcaaaucccu cuacgucaaa     1500

ggugaaccca ucauaaacuu cuacgacccg cuuguguucc cauccgacga guucgacgcc     1560

agcaucagcc aggucaacga aaagaucaac caaucccuag ccuucauccg caaaagcgac     1620

gaacuacuac acaacgucaa cgccggaaaa uccacaacca acaucaugau caccaccauc     1680

aucaucguca ucaucguaau ccuacucucu cucaucgccg ucggccuccu acuguacugu     1740

aaagcccgau agggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  727
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  727
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagau aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  728
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  728
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  729
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  729
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgcu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  730
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  730
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  731
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  731
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  732
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  732
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  733
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  733
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  734
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  734
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauacucaa agccaacgca      120

auaacaacaa uacuaacagc aguaacauuc ugcuucgcau caggacaaaa caucacagaa      180

gaauuuuacc aaaguacaug cagugcaguc ucuaaaggau accucagugc cuuacgcaca      240

ggaugguaca caucaguaau aacaaucgaa cuuucaaaca uaaaagaaaa caaaugcaau      300

ggaaccgacg ccaaaguaaa acuaaucaaa caagaacuag acaaauauaa aaaugcagua      360

acagaauuac aacuccuaau gcaauccaca ccagcaacaa auaacagagc aagacgagaa      420

cucccucgau ucaugaauua cacauuaaac aacgcaaaaa aaacuaacgu aacuuuauca      480

aaaaaaagaa aacguagauu ucuaggauuc cuacuaggcg uaggguccgc cauugcauca      540

ggaguagcag uuagcaaagu auuacauuua gaaggagaag uaaauaaaau caaaagcgca      600

cuacucucaa ccaacaaagc aguaguauca cucucaaacg gaguaucagu acuaacaucc      660

aaaguacucg accucaaaaa cuacauagac aaacaauuac uacccauagu aaacaaacaa      720

ucaugcucua uaucaaauau cgaaacagua aucgaauuuc aacaaaaaaa caaucgacua      780

cuugaaauaa caagagaguu cuccgucaau gccggaguca ccacaccagu cucaacauac      840

augcuaacca acucugaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa      900

aaaaaacuaa ugucaaauaa cguacaaaua guacgacaac aaaguuauuc cauaaugagu      960

auaaucaaag aagaaguguu agcauacgua guccaacuac cauuauaugg aguaauagac     1020

acaccauguu ggaaauuaca caccucacca cucugcacua ccaauacaaa agaaggcuca     1080

aauauaugcc uaacucgcac agacagaggc ugguacugcg auaacgcagg auccguaucu     1140

uucuuucccc aagcagaaac uugcaaagua caaucaaaca gagucuucug cgacaccaug     1200

aauagucuca cauuaccauc ugaaguaaac cuauguaacg uagauauauu caauccaaaa     1260

uacgacugca aaauaaugac aucaaaaacc gacgucucua gcaguguaau cacaucacua     1320

ggagcaauag uaagcugcua uggaaaaaca aaauguacag caucaaacaa aaacagggga     1380

auaauaaaaa ccuucucaaa cggaugugac uacguaucaa auaaaggcgu agacacagua     1440

agcguaggaa acacccuaua cuacguuaac aaacaagaag ggaaaucauu auacguaaaa     1500

ggagaaccaa uaauaaacuu cuacgaucca cucguauucc cauccgacga auuugacgcc     1560

agcauauccc aaguuaacga aaaaauaaac caaucacuug cauuuauacg aaaaucugau     1620

gaacuucucc acaacguaaa ugcaggaaaa uccaccacca auauaaugau cacaacuauc     1680

aucauaguaa uaaucgucau uuuacuauca uuaauagcag uuggccuacu ucuauacugc     1740

aaagcaagau aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  735
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  735
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agccaacgcg      120

aucaccacca uccuaacggc agucaccuuc ugcuucgcau caggccaaaa caucacagaa      180

gaguucuacc aaagcacaug cuccgccgua uccaaaggcu accucagcgc ccuacgcaca      240

ggcugguaca caucugucau caccauagaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacugacg ccaaaguaaa gcugaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacucc aacuacucau gcaauccacc ccugcaacca acaacagggc ccgccgcgaa      420

cucccccgcu ucaugaacua cacuuuaaac aacgccaaaa agaccaacgu cacacucagc      480

aagaaacgga aacgacgauu ccuaggguuu cuccuaggcg ucggcucggc aaucgccucc      540

ggcgucgccg uaagcaaagu acuacaccua gaaggcgaag ugaacaaaau caaaagugcc      600

cuucucucca ccaacaaggc cguagucucu cuauccaacg gagucucagu ccucaccuca      660

aagguccucg accucaaaaa cuacaucgac aaacaacuac uccccauugu caacaagcag      720

ucaugcucca uaucaaacau cgaaaccguc aucgaguucc aacagaaaaa caaccgacuc      780

cucgaaauaa ccagagaguu cucggucaac gccggcguca ccaccccagu cagcaccuac      840

augcucacua acuccgaacu ccuaucccuc aucaacgaca ugccaauuac caacgaccaa      900

aagaaacuaa ugucgaacaa cguucaaauc guccgacaac aaaguuacuc caucaugagc      960

auaaucaaag aagaaguucu agcguacguc guccaacucc cacuauacgg cgucaucgac     1020

acuccgugcu ggaaacucca cacaucaccc cuauguacaa ccaacacaaa agaaggcagc     1080

aacaucugcc ucacccgcac cgaccgaggg ugguauugcg auaacgcugg cagcgucucc     1140

uucuuccccc aagccgaaac cugcaaaguc caaucaaaca gaguauucug cgacaccaug     1200

aacucccuua cucucccuag cgaagucaac cucugcaacg uugacauauu caaccccaaa     1260

uacgacugca aaaucaugac cuccaagacc gacgucuccu ccuccgucau cacaucucua     1320

ggugccauug ucuccugcua cggaaaaacc aaaugcacag ccuccaacaa aaaccgcggc     1380

aucauaaaaa ccuucuccaa cggcugcgac uacgucagua auaaaggcgu cgacacggua     1440

uccguuggga auacgcuuua cuacguaaau aaacaagaag gcaaaucccu cuacgucaaa     1500

ggugaaccca ucauaaacuu cuacgacccg cuuguguucc cauccgacga guucgacgcc     1560

agcaucagcc aggucaacga aaagaucaac caaucccuag ccuucauccg caaaagcgac     1620

gaacuacuac acaacgucaa cgccggaaaa uccacaacca acaucaugau caccaccauc     1680

aucaucguca ucaucguaau ccuacucucu cucaucgccg ucggccuccu acuguacugu     1740

aaagcccgau agggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  736
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  736
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaguugc uaauccucaa agcaaaugca      120

auuaccacaa uccucacugc agucacauuu uguuuugcuu cuggucaaaa caucacugaa      180

gaauuuuauc aaucaacaug cagugcaguu agcaaaggcu aucuuagugc ucugagaacu      240

gguugguaua ccaguguuau aacuauagaa uuaaguaaua ucaaggaaaa uaaguguaau      300

ggaacagaug cuaagguaaa auugauaaaa caagaauuag auaaauauaa aaaugcugua      360

acagaauugc aguugcucau gcaaagcaca ccagcaacaa acaaucgagc cagaagagaa      420

cuaccaaggu uuaugaauua uacacucaac aaugccaaaa aaaccaaugu aacauuaagc      480

aagaaaagga aaagaagauu ucuugguuuu uuguuaggug uuggaucugc aaucgccagu      540

ggcguugcug uaucuaaggu ccugcaccua gaaggggaag ugaacaagau caaaagugcu      600

cuacuaucca caaacaaggc uguagucagc uuaucaaaug gaguuagugu cuuaaccagc      660

aaaguguuag accucaaaaa cuauauagau aaacaauugu uaccuauugu gaacaagcaa      720

agcugcagca uaucaaauau agaaacugug auagaguucc aacaaaagaa caacagacua      780

cuagagauua ccagggaauu uaguguuaau gcagguguaa cuacaccugu aagcacuuac      840

auguuaacua auagugaauu auugucauua aucaaugaua ugccuauaac aaaugaucag      900

aaaaaguuaa uguccaacaa uguucaaaua guuagacagc aaaguuacuc uaucaugucc      960

auaauaaaag aggaagucuu agcauaugua guacaauuac cacuauaugg uguuauagau     1020

acacccuguu ggaaacuaca cacauccccu cuauguacaa ccaacacaaa agaagggucc     1080

aacaucuguu uaacaagaac ugacagagga ugguacugug acaaugcagg aucaguaucu     1140

uucuucccac aagcugaaac auguaaaguu caaucaaauc gaguauuuug ugacacaaug     1200

aacaguuuaa cauuaccaag ugaaguaaau cucugcaaug uugacauauu caaccccaaa     1260

uaugauugua aaauuaugac uucaaaaaca gauguaagca gcuccguuau cacaucucua     1320

ggagccauug ugucaugcua uggcaaaacu aaauguacag cauccaauaa aaaucgugga     1380

aucauaaaga cauuuucuaa cgggugcgau uauguaucaa auaaaggggu ggacacugug     1440

ucuguaggua acacauuaua uuauguaaau aagcaagaag guaaaagucu cuauguaaaa     1500

ggugaaccaa uaauaaauuu cuaugaccca uuaguauucc ccucugauga auuugaugca     1560

ucaauaucuc aagucaacga gaagauuaac cagagccuag cauuuauucg uaaauccgau     1620

gaauuauuac auaauguaaa ugcugguaaa uccaccacaa auaucaugau aacuacuaua     1680

auuauaguga uuauaguaau auuguuauca uuaauugcug uuggacugcu cuuauacugu     1740

aaggccagau aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  737
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  737
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccaccug cagcgccguc uccaaggggu accucagcgc ccugcggacg      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  738
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  738
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg uguccaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccucc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccaucgu caacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccgccuc      780

cuggagauca cccgggaguu cagcgugaac gcggggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccgccagc aguccuacag caucaugucc      960

aucaucaagg aggaggugcu ggccuacgug guccagcugc cgcucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcggac cgaccgcggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaacc ggguguucug cgacaccaug     1200

aacucccuga cgcugccgag cgaggucaac cucugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgucau caccucccug     1320

ggggccaucg ugagcugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacaccgug     1440

uccgugggga acacccugua cuacgucaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cguccgacga guucgacgcc     1560

agcaucuccc aggucaacga gaagaucaac cagagccugg ccuucauccg gaaguccgac     1620

gagcuccugc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgucau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcgcgcu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  739
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  739
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucuccaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccucc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccaucgu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugucc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  740
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  740
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuaguaaggu gcugcaccuu gaaggugagg ucaacaaaau caaguccgcg      600

uugcugucua caaauaaagc agugguaagc cuauccaacg ggguuucagu gcucacuucu      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaaucgu gaacaaacag      720

agcuguucua uuuccaacau cgaaaccgug auagaguucc agcagaagaa uaaccggcuc      780

cuggagauua cacgcgaauu uucagucaau gccggaguua ccacgccggu gagcacuuac      840

auguuaacaa acagugagcu gcucucucuu aucaaugaca ugcccauuac caacgaucaa      900

aagaaacuga uguccaauaa cguacagauc gugagacagc agagcuauuc gaucaugucu      960

auuauaaagg aagaggucuu ggcuuacgug guucaacuac cucuguacgg cgugaucgac     1020

acuccaugcu ggaaacucca uacaucccca cuguguacca cgaauaccaa ggaaggcuca     1080

aacauuugcc uuacaaggac ugaucggggg ugguauugug acaaugccgg aagugucagc     1140

uucuuuccuc aggcagagac cugcaaagug caguccaacc gcguauucug ugauacaaug     1200

aauagucuga cuuugccaag cgagguuaac cucugcaaug uggacaucuu uaaccccaag     1260

uacgauugua agauaaugac cucaaaaaca gacgucaguu ccagcgugau uaccucucug     1320

ggugcuaucg ucucaugcua uggcaagacu aaaugcacgg ccaguaacaa gaaucgaggg     1380

aucauuaaaa cauucagcaa cggaugugau uacgugucca auaagggcgu ugacaccgug     1440

ucuguaggua acacuuuaua uuacgucaau aagcaagaag ggaaaucgcu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuaguuuucc cgagcgauga auuugacgcg     1560

uccauaucac aggugaauga gaaaaucaac cagagucucg ccuucauuag aaagucugau     1620

gaacugcuuc acaaugucaa cgcaggcaaa agcaccacaa auaucaugau caccacuauu     1680

auaaucguga uuaucguaau uuugcugucc cucaucgcug ugggccugcu ucuguacugc     1740

aaggccaggu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  741
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  741
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugagcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccagc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccaucgu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugagc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  742
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  742
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug ugagcaaggu ccuucaccug gaaggagagg ugaacaaaau caagucugcc      600

cuccugucca cgaauaaagc uguugugagc cugucuaacg gcgucuccgu gcucacaagc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgaucgu caacaaacag      720

ucuuguucca uuagcaacau cgaaaccguu auugaguucc agcagaagaa uaaccgccug      780

cuugagauca caagagaauu uuccgugaau gccggcguga ccacccccgu cucuacauac      840

augcugacga acagcgagcu ccugucccug aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuca ugagcaauaa cgugcagauc guucggcagc agucuuauuc cauuaugagc      960

aucauuaagg aagaggugcu ggcguacguc gugcaacuuc cccuguacgg gguuaucgac     1020

acaccuugcu ggaaacucca uaccucuccc cuguguacaa ccaauacgaa ggaaggaagc     1080

aacaucugcc uuacacgcac cgauagaggc ugguauugug acaaugccgg guccgugucu     1140

uucuuuccuc aggcugagac cugcaaaguc cagagcaacc ggguguucug ugauacaaug     1200

aacucccuga cccucccgag cgaggucaau cugugcaaug uggacauuuu uaaccccaag     1260

uacgauugua agaucaugac aucuaaaacg gacguuucca gcucugugau uaccucccug     1320

ggagccaucg ucagcugcua uggcaagaca aaaugcaccg cuuccaacaa gaaucgcggg     1380

auuaucaaaa cauucucuaa cggaugugau uacgugagca auaagggcgu ugacaccgug     1440

uccgucggca acacgcucua uuacgugaau aagcaagaag ggaaaucucu guaugugaag     1500

ggagagccua ucauuaacuu uuacgacccc cuuguuuucc cuagcgauga auuugacgcc     1560

uccaucagcc aggucaauga gaaaauuaac cagucucugg ccuucaucag aaaguccgau     1620

gaacuccugc acaaugugaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgucau ucugcuuucu cucaucgcgg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  743
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  743
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauacucaa agccaacgca      120

auaacaacaa uacuaacagc aguaacauuc ugcuucgcau caggacaaaa caucacagaa      180

gaauuuuacc aaaguacaug cagugcaguc ucuaaaggau accucagugc cuuacgcaca      240

ggaugguaca caucaguaau aacaaucgaa cuuucaaaca uaaaagaaaa caaaugcaau      300

ggaaccgacg ccaaaguaaa acuaaucaaa caagaacuag acaaauauaa aaaugcagua      360

acagaauuac aacuccuaau gcaauccaca ccagcaacaa auaacagagc aagacgagaa      420

cucccucgau ucaugaauua cacauuaaac aacgcaaaaa aaacuaacgu aacuuuauca      480

aaaaaaagaa aacguagauu ucuaggauuc cuacuaggcg uaggguccgc cauugcauca      540

ggaguagcag uuagcaaagu auuacauuua gaaggagaag uaaauaaaau caaaagcgca      600

cuacucucaa ccaacaaagc aguaguauca cucucaaacg gaguaucagu acuaacaucc      660

aaaguacucg accucaaaaa cuacauagac aaacaauuac uacccauagu aaacaaacaa      720

ucaugcucua uaucaaauau cgaaacagua aucgaauuuc aacaaaaaaa caaucgacua      780

cuugaaauaa caagagaguu cuccgucaau gccggaguca ccacaccagu cucaacauac      840

augcuaacca acucugaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa      900

aaaaaacuaa ugucaaauaa cguacaaaua guacgacaac aaaguuauuc cauaaugagu      960

auaaucaaag aagaaguguu agcauacgua guccaacuac cauuauaugg aguaauagac     1020

acaccauguu ggaaauuaca caccucacca cucugcacua ccaauacaaa agaaggcuca     1080

aauauaugcc uaacucgcac agacagaggc ugguacugcg auaacgcagg auccguaucu     1140

uucuuucccc aagcagaaac uugcaaagua caaucaaaca gagucuucug cgacaccaug     1200

aauagucuca cauuaccauc ugaaguaaac cuauguaacg uagauauauu caauccaaaa     1260

uacgacugca aaauaaugac aucaaaaacc gacgucucua gcaguguaau cacaucacua     1320

ggagcaauag uaagcugcua uggaaaaaca aaauguacag caucaaacaa aaacagggga     1380

auaauaaaaa ccuucucaaa cggaugugac uacguaucaa auaaaggcgu agacacagua     1440

agcguaggaa acacccuaua cuacguuaac aaacaagaag ggaaaucauu auacguaaaa     1500

ggagaaccaa uaauaaacuu cuacgaucca cucguauucc cauccgacga auuugacgcc     1560

agcauauccc aaguuaacga aaaaauaaac caaucacuug cauuuauacg aaaaucugau     1620

gaacuucucc acaacguaaa ugcaggaaaa uccaccacca auauaaugau cacaacuauc     1680

aucauaguaa uaaucgucau uuuacuauca uuaauagcag uuggccuacu ucuauacugc     1740

aaagcaagau aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  744
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  744
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agccaacgcg      120

aucaccacca uccuaacggc agucaccuuc ugcuucgcau caggccaaaa caucacagaa      180

gaguucuacc aaagcacaug cuccgccgua uccaaaggcu accucagcgc ccuacgcaca      240

ggcugguaca caucugucau caccauagaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacugacg ccaaaguaaa gcugaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacucc aacuacucau gcaauccacc ccugcaacca acaacagggc ccgccgcgaa      420

cucccccgcu ucaugaacua cacuuuaaac aacgccaaaa agaccaacgu cacacucagc      480

aagaaacgga aacgacgauu ccuaggguuu cuccuaggcg ucggcucggc aaucgccucc      540

ggcgucgccg uaagcaaagu acuacaccua gaaggcgaag ugaacaaaau caaaagugcc      600

cuucucucca ccaacaaggc cguagucucu cuauccaacg gagucucagu ccucaccuca      660

aagguccucg accucaaaaa cuacaucgac aaacaacuac uccccauugu caacaagcag      720

ucaugcucca uaucaaacau cgaaaccguc aucgaguucc aacagaaaaa caaccgacuc      780

cucgaaauaa ccagagaguu cucggucaac gccggcguca ccaccccagu cagcaccuac      840

augcucacua acuccgaacu ccuaucccuc aucaacgaca ugccaauuac caacgaccaa      900

aagaaacuaa ugucgaacaa cguucaaauc guccgacaac aaaguuacuc caucaugagc      960

auaaucaaag aagaaguucu agcguacguc guccaacucc cacuauacgg cgucaucgac     1020

acuccgugcu ggaaacucca cacaucaccc cuauguacaa ccaacacaaa agaaggcagc     1080

aacaucugcc ucacccgcac cgaccgaggg ugguauugcg auaacgcugg cagcgucucc     1140

uucuuccccc aagccgaaac cugcaaaguc caaucaaaca gaguauucug cgacaccaug     1200

aacucccuua cucucccuag cgaagucaac cucugcaacg uugacauauu caaccccaaa     1260

uacgacugca aaaucaugac cuccaagacc gacgucuccu ccuccgucau cacaucucua     1320

ggugccauug ucuccugcua cggaaaaacc aaaugcacag ccuccaacaa aaaccgcggc     1380

aucauaaaaa ccuucuccaa cggcugcgac uacgucagua auaaaggcgu cgacacggua     1440

uccguuggga auacgcuuua cuacguaaau aaacaagaag gcaaaucccu cuacgucaaa     1500

ggugaaccca ucauaaacuu cuacgacccg cuuguguucc cauccgacga guucgacgcc     1560

agcaucagcc aggucaacga aaagaucaac caaucccuag ccuucauccg caaaagcgac     1620

gaacuacuac acaacgucaa cgccggaaaa uccacaacca acaucaugau caccaccauc     1680

aucaucguca ucaucguaau ccuacucucu cucaucgccg ucggccuccu acuguacugu     1740

aaagcccgau agggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  745
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  745
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagauaag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  746
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  746
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  747
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  747
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  748
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  748
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  749
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  749
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  750
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  750
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  751
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  751
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  752
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  752
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uacucaaagc caacgcaaua acaacaauac      120

uaacagcagu aacauucugc uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa      180

guacaugcag ugcagucucu aaaggauacc ucagugccuu acgcacagga ugguacacau      240

caguaauaac aaucgaacuu ucaaacauaa aagaaaacaa augcaaugga accgacgcca      300

aaguaaaacu aaucaaacaa gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac      360

uccuaaugca auccacacca gcaacaaaua acagagcaag acgagaacuc ccucgauuca      420

ugaauuacac auuaaacaac gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac      480

guagauuucu aggauuccua cuaggcguag gguccgccau ugcaucagga guagcaguua      540

gcaaaguauu acauuuagaa ggagaaguaa auaaaaucaa aagcgcacua cucucaacca      600

acaaagcagu aguaucacuc ucaaacggag uaucaguacu aacauccaaa guacucgacc      660

ucaaaaacua cauagacaaa caauuacuac ccauaguaaa caaacaauca ugcucuauau      720

caaauaucga aacaguaauc gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa      780

gagaguucuc cgucaaugcc ggagucacca caccagucuc aacauacaug cuaaccaacu      840

cugaacuccu aucacuaaua aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu      900

caaauaacgu acaaauagua cgacaacaaa guuauuccau aaugaguaua aucaaagaag      960

aaguguuagc auacguaguc caacuaccau uauauggagu aauagacaca ccauguugga     1020

aauuacacac cucaccacuc ugcacuacca auacaaaaga aggcucaaau auaugccuaa     1080

cucgcacaga cagaggcugg uacugcgaua acgcaggauc cguaucuuuc uuuccccaag     1140

cagaaacuug caaaguacaa ucaaacagag ucuucugcga caccaugaau agucucacau     1200

uaccaucuga aguaaaccua uguaacguag auauauucaa uccaaaauac gacugcaaaa     1260

uaaugacauc aaaaaccgac gucucuagca guguaaucac aucacuagga gcaauaguaa     1320

gcugcuaugg aaaaacaaaa uguacagcau caaacaaaaa caggggaaua auaaaaaccu     1380

ucucaaacgg augugacuac guaucaaaua aaggcguaga cacaguaagc guaggaaaca     1440

cccuauacua cguuaacaaa caagaaggga aaucauuaua cguaaaagga gaaccaauaa     1500

uaaacuucua cgauccacuc guauucccau ccgacgaauu ugacgccagc auaucccaag     1560

uuaacgaaaa aauaaaccaa ucacuugcau uuauacgaaa aucugaugaa cuucuccaca     1620

acguaaaugc aggaaaaucc accaccaaua uaaugaucac aacuaucauc auaguaauaa     1680

ucgucauuuu acuaucauua auagcaguug gccuacuucu auacugcaaa gcaagauaag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  753
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  753
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc caacgcgauc accaccaucc      120

uaacggcagu caccuucugc uucgcaucag gccaaaacau cacagaagag uucuaccaaa      180

gcacaugcuc cgccguaucc aaaggcuacc ucagcgcccu acgcacaggc ugguacacau      240

cugucaucac cauagaacuc uccaacauca aagaaaacaa augcaacggc acugacgcca      300

aaguaaagcu gaucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuccaac      360

uacucaugca auccaccccu gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca      420

ugaacuacac uuuaaacaac gccaaaaaga ccaacgucac acucagcaag aaacggaaac      480

gacgauuccu aggguuucuc cuaggcgucg gcucggcaau cgccuccggc gucgccguaa      540

gcaaaguacu acaccuagaa ggcgaaguga acaaaaucaa aagugcccuu cucuccacca      600

acaaggccgu agucucucua uccaacggag ucucaguccu caccucaaag guccucgacc      660

ucaaaaacua caucgacaaa caacuacucc ccauugucaa caagcaguca ugcuccauau      720

caaacaucga aaccgucauc gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca      780

gagaguucuc ggucaacgcc ggcgucacca ccccagucag caccuacaug cucacuaacu      840

ccgaacuccu aucccucauc aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu      900

cgaacaacgu ucaaaucguc cgacaacaaa guuacuccau caugagcaua aucaaagaag      960

aaguucuagc guacgucguc caacucccac uauacggcgu caucgacacu ccgugcugga     1020

aacuccacac aucaccccua uguacaacca acacaaaaga aggcagcaac aucugccuca     1080

cccgcaccga ccgagggugg uauugcgaua acgcuggcag cgucuccuuc uucccccaag     1140

ccgaaaccug caaaguccaa ucaaacagag uauucugcga caccaugaac ucccuuacuc     1200

ucccuagcga agucaaccuc ugcaacguug acauauucaa ccccaaauac gacugcaaaa     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac aucucuaggu gccauugucu     1320

ccugcuacgg aaaaaccaaa ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu     1380

ucuccaacgg cugcgacuac gucaguaaua aaggcgucga cacgguaucc guugggaaua     1440

cgcuuuacua cguaaauaaa caagaaggca aaucccucua cgucaaaggu gaacccauca     1500

uaaacuucua cgacccgcuu guguucccau ccgacgaguu cgacgccagc aucagccagg     1560

ucaacgaaaa gaucaaccaa ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca     1620

acgucaacgc cggaaaaucc acaaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucguaauccu acucucucuc aucgccgucg gccuccuacu guacuguaaa gcccgauagg     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  754
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  754
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaguugcuaa uccucaaagc aaaugcaauu accacaaucc      120

ucacugcagu cacauuuugu uuugcuucug gucaaaacau cacugaagaa uuuuaucaau      180

caacaugcag ugcaguuagc aaaggcuauc uuagugcucu gagaacuggu ugguauacca      240

guguuauaac uauagaauua aguaauauca aggaaaauaa guguaaugga acagaugcua      300

agguaaaauu gauaaaacaa gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu      360

ugcucaugca aagcacacca gcaacaaaca aucgagccag aagagaacua ccaagguuua      420

ugaauuauac acucaacaau gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa      480

gaagauuucu ugguuuuuug uuagguguug gaucugcaau cgccaguggc guugcuguau      540

cuaagguccu gcaccuagaa ggggaaguga acaagaucaa aagugcucua cuauccacaa      600

acaaggcugu agucagcuua ucaaauggag uuagugucuu aaccagcaaa guguuagacc      660

ucaaaaacua uauagauaaa caauuguuac cuauugugaa caagcaaagc ugcagcauau      720

caaauauaga aacugugaua gaguuccaac aaaagaacaa cagacuacua gagauuacca      780

gggaauuuag uguuaaugca gguguaacua caccuguaag cacuuacaug uuaacuaaua      840

gugaauuauu gucauuaauc aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu      900

ccaacaaugu ucaaauaguu agacagcaaa guuacucuau cauguccaua auaaaagagg      960

aagucuuagc auauguagua caauuaccac uauauggugu uauagauaca cccuguugga     1020

aacuacacac auccccucua uguacaacca acacaaaaga aggguccaac aucuguuuaa     1080

caagaacuga cagaggaugg uacugugaca augcaggauc aguaucuuuc uucccacaag     1140

cugaaacaug uaaaguucaa ucaaaucgag uauuuuguga cacaaugaac aguuuaacau     1200

uaccaaguga aguaaaucuc ugcaauguug acauauucaa ccccaaauau gauuguaaaa     1260

uuaugacuuc aaaaacagau guaagcagcu ccguuaucac aucucuagga gccauugugu     1320

caugcuaugg caaaacuaaa uguacagcau ccaauaaaaa ucguggaauc auaaagacau     1380

uuucuaacgg gugcgauuau guaucaaaua aaggggugga cacugugucu guagguaaca     1440

cauuauauua uguaaauaag caagaaggua aaagucucua uguaaaaggu gaaccaauaa     1500

uaaauuucua ugacccauua guauuccccu cugaugaauu ugaugcauca auaucucaag     1560

ucaacgagaa gauuaaccag agccuagcau uuauucguaa auccgaugaa uuauuacaua     1620

auguaaaugc ugguaaaucc accacaaaua ucaugauaac uacuauaauu auagugauua     1680

uaguaauauu guuaucauua auugcuguug gacugcucuu auacuguaag gccagauaag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  755
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  755
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccaccugcag cgccgucucc aagggguacc ucagcgcccu gcggacgggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  756
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  756
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

ccaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuccaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccaucgucaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccgccuccug gagaucaccc      780

gggaguucag cgugaacgcg ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc ccaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cgccagcagu ccuacagcau cauguccauc aucaaggagg      960

aggugcuggc cuacgugguc cagcugccgc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcag cgucuccuuc uucccccagg     1140

ccgagaccug caaggugcag agcaaccggg uguucugcga caccaugaac ucccugacgc     1200

ugccgagcga ggucaaccuc ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgucaucac cucccugggg gccaucguga     1320

gcugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgucga caccgugucc guggggaaca     1440

cccuguacua cgucaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccgu ccgacgaguu cgacgccagc aucucccagg     1560

ucaacgagaa gaucaaccag agccuggccu ucauccggaa guccgacgag cuccugcaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgucauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  757
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  757
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

ccaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuccaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccaucgucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau cauguccauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  758
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  758
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguua      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa guccgcguug cugucuacaa      600

auaaagcagu gguaagccua uccaacgggg uuucagugcu cacuucuaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caaucgugaa caaacagagc uguucuauuu      720

ccaacaucga aaccgugaua gaguuccagc agaagaauaa ccggcuccug gagauuacac      780

gcgaauuuuc agucaaugcc ggaguuacca cgccggugag cacuuacaug uuaacaaaca      840

gugagcugcu cucucuuauc aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu      900

ccaauaacgu acagaucgug agacagcaga gcuauucgau caugucuauu auaaaggaag      960

aggucuuggc uuacgugguu caacuaccuc uguacggcgu gaucgacacu ccaugcugga     1020

aacuccauac auccccacug uguaccacga auaccaagga aggcucaaac auuugccuua     1080

caaggacuga ucgggggugg uauugugaca augccggaag ugucagcuuc uuuccucagg     1140

cagagaccug caaagugcag uccaaccgcg uauucuguga uacaaugaau agucugacuu     1200

ugccaagcga gguuaaccuc ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga     1260

uaaugaccuc aaaaacagac gucaguucca gcgugauuac cucucugggu gcuaucgucu     1320

caugcuaugg caagacuaaa ugcacggcca guaacaagaa ucgagggauc auuaaaacau     1380

ucagcaacgg augugauuac guguccaaua agggcguuga caccgugucu guagguaaca     1440

cuuuauauua cgucaauaag caagaaggga aaucgcugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccua guuuucccga gcgaugaauu ugacgcgucc auaucacagg     1560

ugaaugagaa aaucaaccag agucucgccu ucauuagaaa gucugaugaa cugcuucaca     1620

augucaacgc aggcaaaagc accacaaaua ucaugaucac cacuauuaua aucgugauua     1680

ucguaauuuu gcugucccuc aucgcugugg gccugcuucu guacugcaag gccaggugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  759
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  759
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccguga      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccagcaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccaucgugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugagcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  760
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  760
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcuguga      540

gcaagguccu ucaccuggaa ggagagguga acaaaaucaa gucugcccuc cuguccacga      600

auaaagcugu ugugagccug ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgaucgucaa caaacagucu uguuccauua      720

gcaacaucga aaccguuauu gaguuccagc agaagaauaa ccgccugcuu gagaucacaa      780

gagaauuuuc cgugaaugcc ggcgugacca cccccgucuc uacauacaug cugacgaaca      840

gcgagcuccu gucccugauc aaugacaugc cuauuaccaa cgaucaaaag aaacucauga      900

gcaauaacgu gcagaucguu cggcagcagu cuuauuccau uaugagcauc auuaaggaag      960

aggugcuggc guacgucgug caacuucccc uguacggggu uaucgacaca ccuugcugga     1020

aacuccauac cucuccccug uguacaacca auacgaagga aggaagcaac aucugccuua     1080

cacgcaccga uagaggcugg uauugugaca augccggguc cgugucuuuc uuuccucagg     1140

cugagaccug caaaguccag agcaaccggg uguucuguga uacaaugaac ucccugaccc     1200

ucccgagcga ggucaaucug ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga     1260

ucaugacauc uaaaacggac guuuccagcu cugugauuac cucccuggga gccaucguca     1320

gcugcuaugg caagacaaaa ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau     1380

ucucuaacgg augugauuac gugagcaaua agggcguuga caccgugucc gucggcaaca     1440

cgcucuauua cgugaauaag caagaaggga aaucucugua ugugaaggga gagccuauca     1500

uuaacuuuua cgacccccuu guuuucccua gcgaugaauu ugacgccucc aucagccagg     1560

ucaaugagaa aauuaaccag ucucuggccu ucaucagaaa guccgaugaa cuccugcaca     1620

augugaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgucauucu gcuuucucuc aucgcggugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  761
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  761
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uacucaaagc caacgcaaua acaacaauac      120

uaacagcagu aacauucugc uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa      180

guacaugcag ugcagucucu aaaggauacc ucagugccuu acgcacagga ugguacacau      240

caguaauaac aaucgaacuu ucaaacauaa aagaaaacaa augcaaugga accgacgcca      300

aaguaaaacu aaucaaacaa gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac      360

uccuaaugca auccacacca gcaacaaaua acagagcaag acgagaacuc ccucgauuca      420

ugaauuacac auuaaacaac gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac      480

guagauuucu aggauuccua cuaggcguag gguccgccau ugcaucagga guagcaguua      540

gcaaaguauu acauuuagaa ggagaaguaa auaaaaucaa aagcgcacua cucucaacca      600

acaaagcagu aguaucacuc ucaaacggag uaucaguacu aacauccaaa guacucgacc      660

ucaaaaacua cauagacaaa caauuacuac ccauaguaaa caaacaauca ugcucuauau      720

caaauaucga aacaguaauc gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa      780

gagaguucuc cgucaaugcc ggagucacca caccagucuc aacauacaug cuaaccaacu      840

cugaacuccu aucacuaaua aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu      900

caaauaacgu acaaauagua cgacaacaaa guuauuccau aaugaguaua aucaaagaag      960

aaguguuagc auacguaguc caacuaccau uauauggagu aauagacaca ccauguugga     1020

aauuacacac cucaccacuc ugcacuacca auacaaaaga aggcucaaau auaugccuaa     1080

cucgcacaga cagaggcugg uacugcgaua acgcaggauc cguaucuuuc uuuccccaag     1140

cagaaacuug caaaguacaa ucaaacagag ucuucugcga caccaugaau agucucacau     1200

uaccaucuga aguaaaccua uguaacguag auauauucaa uccaaaauac gacugcaaaa     1260

uaaugacauc aaaaaccgac gucucuagca guguaaucac aucacuagga gcaauaguaa     1320

gcugcuaugg aaaaacaaaa uguacagcau caaacaaaaa caggggaaua auaaaaaccu     1380

ucucaaacgg augugacuac guaucaaaua aaggcguaga cacaguaagc guaggaaaca     1440

cccuauacua cguuaacaaa caagaaggga aaucauuaua cguaaaagga gaaccaauaa     1500

uaaacuucua cgauccacuc guauucccau ccgacgaauu ugacgccagc auaucccaag     1560

uuaacgaaaa aauaaaccaa ucacuugcau uuauacgaaa aucugaugaa cuucuccaca     1620

acguaaaugc aggaaaaucc accaccaaua uaaugaucac aacuaucauc auaguaauaa     1680

ucgucauuuu acuaucauua auagcaguug gccuacuucu auacugcaaa gcaagauaag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  762
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  762
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc caacgcgauc accaccaucc      120

uaacggcagu caccuucugc uucgcaucag gccaaaacau cacagaagag uucuaccaaa      180

gcacaugcuc cgccguaucc aaaggcuacc ucagcgcccu acgcacaggc ugguacacau      240

cugucaucac cauagaacuc uccaacauca aagaaaacaa augcaacggc acugacgcca      300

aaguaaagcu gaucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuccaac      360

uacucaugca auccaccccu gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca      420

ugaacuacac uuuaaacaac gccaaaaaga ccaacgucac acucagcaag aaacggaaac      480

gacgauuccu aggguuucuc cuaggcgucg gcucggcaau cgccuccggc gucgccguaa      540

gcaaaguacu acaccuagaa ggcgaaguga acaaaaucaa aagugcccuu cucuccacca      600

acaaggccgu agucucucua uccaacggag ucucaguccu caccucaaag guccucgacc      660

ucaaaaacua caucgacaaa caacuacucc ccauugucaa caagcaguca ugcuccauau      720

caaacaucga aaccgucauc gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca      780

gagaguucuc ggucaacgcc ggcgucacca ccccagucag caccuacaug cucacuaacu      840

ccgaacuccu aucccucauc aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu      900

cgaacaacgu ucaaaucguc cgacaacaaa guuacuccau caugagcaua aucaaagaag      960

aaguucuagc guacgucguc caacucccac uauacggcgu caucgacacu ccgugcugga     1020

aacuccacac aucaccccua uguacaacca acacaaaaga aggcagcaac aucugccuca     1080

cccgcaccga ccgagggugg uauugcgaua acgcuggcag cgucuccuuc uucccccaag     1140

ccgaaaccug caaaguccaa ucaaacagag uauucugcga caccaugaac ucccuuacuc     1200

ucccuagcga agucaaccuc ugcaacguug acauauucaa ccccaaauac gacugcaaaa     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac aucucuaggu gccauugucu     1320

ccugcuacgg aaaaaccaaa ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu     1380

ucuccaacgg cugcgacuac gucaguaaua aaggcgucga cacgguaucc guugggaaua     1440

cgcuuuacua cguaaauaaa caagaaggca aaucccucua cgucaaaggu gaacccauca     1500

uaaacuucua cgacccgcuu guguucccau ccgacgaguu cgacgccagc aucagccagg     1560

ucaacgaaaa gaucaaccaa ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca     1620

acgucaacgc cggaaaaucc acaaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucguaauccu acucucucuc aucgccgucg gccuccuacu guacuguaaa gcccgauagg     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  763
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  763
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  764
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  764
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  765
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  765
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  766
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  766
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  767
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  767
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccaggug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  768
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  768
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  769
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  769
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccggug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  770
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  770
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauacucaaa gccaacgcaa uaacaacaau acuaacagca      120

guaacauucu gcuucgcauc aggacaaaac aucacagaag aauuuuacca aaguacaugc      180

agugcagucu cuaaaggaua ccucagugcc uuacgcacag gaugguacac aucaguaaua      240

acaaucgaac uuucaaacau aaaagaaaac aaaugcaaug gaaccgacgc caaaguaaaa      300

cuaaucaaac aagaacuaga caaauauaaa aaugcaguaa cagaauuaca acuccuaaug      360

caauccacac cagcaacaaa uaacagagca agacgagaac ucccucgauu caugaauuac      420

acauuaaaca acgcaaaaaa aacuaacgua acuuuaucaa aaaaaagaaa acguagauuu      480

cuaggauucc uacuaggcgu aggguccgcc auugcaucag gaguagcagu uagcaaagua      540

uuacauuuag aaggagaagu aaauaaaauc aaaagcgcac uacucucaac caacaaagca      600

guaguaucac ucucaaacgg aguaucagua cuaacaucca aaguacucga ccucaaaaac      660

uacauagaca aacaauuacu acccauagua aacaaacaau caugcucuau aucaaauauc      720

gaaacaguaa ucgaauuuca acaaaaaaac aaucgacuac uugaaauaac aagagaguuc      780

uccgucaaug ccggagucac cacaccaguc ucaacauaca ugcuaaccaa cucugaacuc      840

cuaucacuaa uaaaugacau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      900

guacaaauag uacgacaaca aaguuauucc auaaugagua uaaucaaaga agaaguguua      960

gcauacguag uccaacuacc auuauaugga guaauagaca caccauguug gaaauuacac     1020

accucaccac ucugcacuac caauacaaaa gaaggcucaa auauaugccu aacucgcaca     1080

gacagaggcu gguacugcga uaacgcagga uccguaucuu ucuuucccca agcagaaacu     1140

ugcaaaguac aaucaaacag agucuucugc gacaccauga auagucucac auuaccaucu     1200

gaaguaaacc uauguaacgu agauauauuc aauccaaaau acgacugcaa aauaaugaca     1260

ucaaaaaccg acgucucuag caguguaauc acaucacuag gagcaauagu aagcugcuau     1320

ggaaaaacaa aauguacagc aucaaacaaa aacaggggaa uaauaaaaac cuucucaaac     1380

ggaugugacu acguaucaaa uaaaggcgua gacacaguaa gcguaggaaa cacccuauac     1440

uacguuaaca aacaagaagg gaaaucauua uacguaaaag gagaaccaau aauaaacuuc     1500

uacgauccac ucguauuccc auccgacgaa uuugacgcca gcauauccca aguuaacgaa     1560

aaaauaaacc aaucacuugc auuuauacga aaaucugaug aacuucucca caacguaaau     1620

gcaggaaaau ccaccaccaa uauaaugauc acaacuauca ucauaguaau aaucgucauu     1680

uuacuaucau uaauagcagu uggccuacuu cuauacugca aagcaagaua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  771
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  771
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gccaacgcga ucaccaccau ccuaacggca      120

gucaccuucu gcuucgcauc aggccaaaac aucacagaag aguucuacca aagcacaugc      180

uccgccguau ccaaaggcua ccucagcgcc cuacgcacag gcugguacac aucugucauc      240

accauagaac ucuccaacau caaagaaaac aaaugcaacg gcacugacgc caaaguaaag      300

cugaucaaac aagaacucga caaauacaaa aacgcaguca ccgaacucca acuacucaug      360

caauccaccc cugcaaccaa caacagggcc cgccgcgaac ucccccgcuu caugaacuac      420

acuuuaaaca acgccaaaaa gaccaacguc acacucagca agaaacggaa acgacgauuc      480

cuaggguuuc uccuaggcgu cggcucggca aucgccuccg gcgucgccgu aagcaaagua      540

cuacaccuag aaggcgaagu gaacaaaauc aaaagugccc uucucuccac caacaaggcc      600

guagucucuc uauccaacgg agucucaguc cucaccucaa agguccucga ccucaaaaac      660

uacaucgaca aacaacuacu ccccauuguc aacaagcagu caugcuccau aucaaacauc      720

gaaaccguca ucgaguucca acagaaaaac aaccgacucc ucgaaauaac cagagaguuc      780

ucggucaacg ccggcgucac caccccaguc agcaccuaca ugcucacuaa cuccgaacuc      840

cuaucccuca ucaacgacau gccaauuacc aacgaccaaa agaaacuaau gucgaacaac      900

guucaaaucg uccgacaaca aaguuacucc aucaugagca uaaucaaaga agaaguucua      960

gcguacgucg uccaacuccc acuauacggc gucaucgaca cuccgugcug gaaacuccac     1020

acaucacccc uauguacaac caacacaaaa gaaggcagca acaucugccu cacccgcacc     1080

gaccgagggu gguauugcga uaacgcuggc agcgucuccu ucuuccccca agccgaaacc     1140

ugcaaagucc aaucaaacag aguauucugc gacaccauga acucccuuac ucucccuagc     1200

gaagucaacc ucugcaacgu ugacauauuc aaccccaaau acgacugcaa aaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc acaucucuag gugccauugu cuccugcuac     1320

ggaaaaacca aaugcacagc cuccaacaaa aaccgcggca ucauaaaaac cuucuccaac     1380

ggcugcgacu acgucaguaa uaaaggcguc gacacgguau ccguugggaa uacgcuuuac     1440

uacguaaaua aacaagaagg caaaucccuc uacgucaaag gugaacccau cauaaacuuc     1500

uacgacccgc uuguguuccc auccgacgag uucgacgcca gcaucagcca ggucaacgaa     1560

aagaucaacc aaucccuagc cuucauccgc aaaagcgacg aacuacuaca caacgucaac     1620

gccggaaaau ccacaaccaa caucaugauc accaccauca ucaucgucau caucguaauc     1680

cuacucucuc ucaucgccgu cggccuccua cuguacugua aagcccgaua gggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  772
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  772
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaguugcu aauccucaaa gcaaaugcaa uuaccacaau ccucacugca      120

gucacauuuu guuuugcuuc uggucaaaac aucacugaag aauuuuauca aucaacaugc      180

agugcaguua gcaaaggcua ucuuagugcu cugagaacug guugguauac caguguuaua      240

acuauagaau uaaguaauau caaggaaaau aaguguaaug gaacagaugc uaagguaaaa      300

uugauaaaac aagaauuaga uaaauauaaa aaugcuguaa cagaauugca guugcucaug      360

caaagcacac cagcaacaaa caaucgagcc agaagagaac uaccaagguu uaugaauuau      420

acacucaaca augccaaaaa aaccaaugua acauuaagca agaaaaggaa aagaagauuu      480

cuugguuuuu uguuaggugu uggaucugca aucgccagug gcguugcugu aucuaagguc      540

cugcaccuag aaggggaagu gaacaagauc aaaagugcuc uacuauccac aaacaaggcu      600

guagucagcu uaucaaaugg aguuaguguc uuaaccagca aaguguuaga ccucaaaaac      660

uauauagaua aacaauuguu accuauugug aacaagcaaa gcugcagcau aucaaauaua      720

gaaacuguga uagaguucca acaaaagaac aacagacuac uagagauuac cagggaauuu      780

aguguuaaug cagguguaac uacaccugua agcacuuaca uguuaacuaa uagugaauua      840

uugucauuaa ucaaugauau gccuauaaca aaugaucaga aaaaguuaau guccaacaau      900

guucaaauag uuagacagca aaguuacucu aucaugucca uaauaaaaga ggaagucuua      960

gcauauguag uacaauuacc acuauauggu guuauagaua cacccuguug gaaacuacac     1020

acauccccuc uauguacaac caacacaaaa gaagggucca acaucuguuu aacaagaacu     1080

gacagaggau gguacuguga caaugcagga ucaguaucuu ucuucccaca agcugaaaca     1140

uguaaaguuc aaucaaaucg aguauuuugu gacacaauga acaguuuaac auuaccaagu     1200

gaaguaaauc ucugcaaugu ugacauauuc aaccccaaau augauuguaa aauuaugacu     1260

ucaaaaacag auguaagcag cuccguuauc acaucucuag gagccauugu gucaugcuau     1320

ggcaaaacua aauguacagc auccaauaaa aaucguggaa ucauaaagac auuuucuaac     1380

gggugcgauu auguaucaaa uaaaggggug gacacugugu cuguagguaa cacauuauau     1440

uauguaaaua agcaagaagg uaaaagucuc uauguaaaag gugaaccaau aauaaauuuc     1500

uaugacccau uaguauuccc cucugaugaa uuugaugcau caauaucuca agucaacgag     1560

aagauuaacc agagccuagc auuuauucgu aaauccgaug aauuauuaca uaauguaaau     1620

gcugguaaau ccaccacaaa uaucaugaua acuacuauaa uuauagugau uauaguaaua     1680

uuguuaucau uaauugcugu uggacugcuc uuauacugua aggccagaua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  773
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  773
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccaccugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggacgg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  774
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  774
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu guccaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccucca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccaucguc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccgccucc uggagaucac ccgggaguuc      780

agcgugaacg cgggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gcccaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccgccagca guccuacagc aucaugucca ucaucaagga ggaggugcug      960

gccuacgugg uccagcugcc gcucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc agcgucuccu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaaccg gguguucugc gacaccauga acucccugac gcugccgagc     1200

gaggucaacc ucugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgucauc accucccugg gggccaucgu gagcugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcguc gacaccgugu ccguggggaa cacccuguac     1440

uacgucaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc guccgacgag uucgacgcca gcaucuccca ggucaacgag     1560

aagaucaacc agagccuggc cuucauccgg aaguccgacg agcuccugca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgucauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcgcgcug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  775
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  775
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cuccaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccucca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccaucguc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugucca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  776
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  776
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uaguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aaguccgcgu ugcugucuac aaauaaagca      600

gugguaagcc uauccaacgg gguuucagug cucacuucua agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaaucgug aacaaacaga gcuguucuau uuccaacauc      720

gaaaccguga uagaguucca gcagaagaau aaccggcucc uggagauuac acgcgaauuu      780

ucagucaaug ccggaguuac cacgccggug agcacuuaca uguuaacaaa cagugagcug      840

cucucucuua ucaaugacau gcccauuacc aacgaucaaa agaaacugau guccaauaac      900

guacagaucg ugagacagca gagcuauucg aucaugucua uuauaaagga agaggucuug      960

gcuuacgugg uucaacuacc ucuguacggc gugaucgaca cuccaugcug gaaacuccau     1020

acauccccac uguguaccac gaauaccaag gaaggcucaa acauuugccu uacaaggacu     1080

gaucgggggu gguauuguga caaugccgga agugucagcu ucuuuccuca ggcagagacc     1140

ugcaaagugc aguccaaccg cguauucugu gauacaauga auagucugac uuugccaagc     1200

gagguuaacc ucugcaaugu ggacaucuuu aaccccaagu acgauuguaa gauaaugacc     1260

ucaaaaacag acgucaguuc cagcgugauu accucucugg gugcuaucgu cucaugcuau     1320

ggcaagacua aaugcacggc caguaacaag aaucgaggga ucauuaaaac auucagcaac     1380

ggaugugauu acguguccaa uaagggcguu gacaccgugu cuguagguaa cacuuuauau     1440

uacgucaaua agcaagaagg gaaaucgcug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uaguuuuccc gagcgaugaa uuugacgcgu ccauaucaca ggugaaugag     1560

aaaaucaacc agagucucgc cuucauuaga aagucugaug aacugcuuca caaugucaac     1620

gcaggcaaaa gcaccacaaa uaucaugauc accacuauua uaaucgugau uaucguaauu     1680

uugcuguccc ucaucgcugu gggccugcuu cuguacugca aggccaggug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  777
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  777
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gagcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccagca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccaucgug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugagca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  778
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  778
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu gagcaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagucugccc uccuguccac gaauaaagcu      600

guugugagcc ugucuaacgg cgucuccgug cucacaagca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgaucguc aacaaacagu cuuguuccau uagcaacauc      720

gaaaccguua uugaguucca gcagaagaau aaccgccugc uugagaucac aagagaauuu      780

uccgugaaug ccggcgugac cacccccguc ucuacauaca ugcugacgaa cagcgagcuc      840

cugucccuga ucaaugacau gccuauuacc aacgaucaaa agaaacucau gagcaauaac      900

gugcagaucg uucggcagca gucuuauucc auuaugagca ucauuaagga agaggugcug      960

gcguacgucg ugcaacuucc ccuguacggg guuaucgaca caccuugcug gaaacuccau     1020

accucucccc uguguacaac caauacgaag gaaggaagca acaucugccu uacacgcacc     1080

gauagaggcu gguauuguga caaugccggg uccgugucuu ucuuuccuca ggcugagacc     1140

ugcaaagucc agagcaaccg gguguucugu gauacaauga acucccugac ccucccgagc     1200

gaggucaauc ugugcaaugu ggacauuuuu aaccccaagu acgauuguaa gaucaugaca     1260

ucuaaaacgg acguuuccag cucugugauu accucccugg gagccaucgu cagcugcuau     1320

ggcaagacaa aaugcaccgc uuccaacaag aaucgcggga uuaucaaaac auucucuaac     1380

ggaugugauu acgugagcaa uaagggcguu gacaccgugu ccgucggcaa cacgcucuau     1440

uacgugaaua agcaagaagg gaaaucucug uaugugaagg gagagccuau cauuaacuuu     1500

uacgaccccc uuguuuuccc uagcgaugaa uuugacgccu ccaucagcca ggucaaugag     1560

aaaauuaacc agucucuggc cuucaucaga aaguccgaug aacuccugca caaugugaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgucauu     1680

cugcuuucuc ucaucgcggu ggggcugcug cucuacugca aggcccggug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  779
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  779
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauacucaaa gccaacgcaa uaacaacaau acuaacagca      120

guaacauucu gcuucgcauc aggacaaaac aucacagaag aauuuuacca aaguacaugc      180

agugcagucu cuaaaggaua ccucagugcc uuacgcacag gaugguacac aucaguaaua      240

acaaucgaac uuucaaacau aaaagaaaac aaaugcaaug gaaccgacgc caaaguaaaa      300

cuaaucaaac aagaacuaga caaauauaaa aaugcaguaa cagaauuaca acuccuaaug      360

caauccacac cagcaacaaa uaacagagca agacgagaac ucccucgauu caugaauuac      420

acauuaaaca acgcaaaaaa aacuaacgua acuuuaucaa aaaaaagaaa acguagauuu      480

cuaggauucc uacuaggcgu aggguccgcc auugcaucag gaguagcagu uagcaaagua      540

uuacauuuag aaggagaagu aaauaaaauc aaaagcgcac uacucucaac caacaaagca      600

guaguaucac ucucaaacgg aguaucagua cuaacaucca aaguacucga ccucaaaaac      660

uacauagaca aacaauuacu acccauagua aacaaacaau caugcucuau aucaaauauc      720

gaaacaguaa ucgaauuuca acaaaaaaac aaucgacuac uugaaauaac aagagaguuc      780

uccgucaaug ccggagucac cacaccaguc ucaacauaca ugcuaaccaa cucugaacuc      840

cuaucacuaa uaaaugacau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      900

guacaaauag uacgacaaca aaguuauucc auaaugagua uaaucaaaga agaaguguua      960

gcauacguag uccaacuacc auuauaugga guaauagaca caccauguug gaaauuacac     1020

accucaccac ucugcacuac caauacaaaa gaaggcucaa auauaugccu aacucgcaca     1080

gacagaggcu gguacugcga uaacgcagga uccguaucuu ucuuucccca agcagaaacu     1140

ugcaaaguac aaucaaacag agucuucugc gacaccauga auagucucac auuaccaucu     1200

gaaguaaacc uauguaacgu agauauauuc aauccaaaau acgacugcaa aauaaugaca     1260

ucaaaaaccg acgucucuag caguguaauc acaucacuag gagcaauagu aagcugcuau     1320

ggaaaaacaa aauguacagc aucaaacaaa aacaggggaa uaauaaaaac cuucucaaac     1380

ggaugugacu acguaucaaa uaaaggcgua gacacaguaa gcguaggaaa cacccuauac     1440

uacguuaaca aacaagaagg gaaaucauua uacguaaaag gagaaccaau aauaaacuuc     1500

uacgauccac ucguauuccc auccgacgaa uuugacgcca gcauauccca aguuaacgaa     1560

aaaauaaacc aaucacuugc auuuauacga aaaucugaug aacuucucca caacguaaau     1620

gcaggaaaau ccaccaccaa uauaaugauc acaacuauca ucauaguaau aaucgucauu     1680

uuacuaucau uaauagcagu uggccuacuu cuauacugca aagcaagaua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  780
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  780
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gccaacgcga ucaccaccau ccuaacggca      120

gucaccuucu gcuucgcauc aggccaaaac aucacagaag aguucuacca aagcacaugc      180

uccgccguau ccaaaggcua ccucagcgcc cuacgcacag gcugguacac aucugucauc      240

accauagaac ucuccaacau caaagaaaac aaaugcaacg gcacugacgc caaaguaaag      300

cugaucaaac aagaacucga caaauacaaa aacgcaguca ccgaacucca acuacucaug      360

caauccaccc cugcaaccaa caacagggcc cgccgcgaac ucccccgcuu caugaacuac      420

acuuuaaaca acgccaaaaa gaccaacguc acacucagca agaaacggaa acgacgauuc      480

cuaggguuuc uccuaggcgu cggcucggca aucgccuccg gcgucgccgu aagcaaagua      540

cuacaccuag aaggcgaagu gaacaaaauc aaaagugccc uucucuccac caacaaggcc      600

guagucucuc uauccaacgg agucucaguc cucaccucaa agguccucga ccucaaaaac      660

uacaucgaca aacaacuacu ccccauuguc aacaagcagu caugcuccau aucaaacauc      720

gaaaccguca ucgaguucca acagaaaaac aaccgacucc ucgaaauaac cagagaguuc      780

ucggucaacg ccggcgucac caccccaguc agcaccuaca ugcucacuaa cuccgaacuc      840

cuaucccuca ucaacgacau gccaauuacc aacgaccaaa agaaacuaau gucgaacaac      900

guucaaaucg uccgacaaca aaguuacucc aucaugagca uaaucaaaga agaaguucua      960

gcguacgucg uccaacuccc acuauacggc gucaucgaca cuccgugcug gaaacuccac     1020

acaucacccc uauguacaac caacacaaaa gaaggcagca acaucugccu cacccgcacc     1080

gaccgagggu gguauugcga uaacgcuggc agcgucuccu ucuuccccca agccgaaacc     1140

ugcaaagucc aaucaaacag aguauucugc gacaccauga acucccuuac ucucccuagc     1200

gaagucaacc ucugcaacgu ugacauauuc aaccccaaau acgacugcaa aaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc acaucucuag gugccauugu cuccugcuac     1320

ggaaaaacca aaugcacagc cuccaacaaa aaccgcggca ucauaaaaac cuucuccaac     1380

ggcugcgacu acgucaguaa uaaaggcguc gacacgguau ccguugggaa uacgcuuuac     1440

uacguaaaua aacaagaagg caaaucccuc uacgucaaag gugaacccau cauaaacuuc     1500

uacgacccgc uuguguuccc auccgacgag uucgacgcca gcaucagcca ggucaacgaa     1560

aagaucaacc aaucccuagc cuucauccgc aaaagcgacg aacuacuaca caacgucaac     1620

gccggaaaau ccacaaccaa caucaugauc accaccauca ucaucgucau caucguaauc     1680

cuacucucuc ucaucgccgu cggccuccua cuguacugua aagcccgaua gggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  781
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  781
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagauaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  782
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  782
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  783
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  783
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  784
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  784
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  785
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  785
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  786
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  786
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  787
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  787
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  788
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  788
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau acucaaagcc      120

aacgcaauaa caacaauacu aacagcagua acauucugcu ucgcaucagg acaaaacauc      180

acagaagaau uuuaccaaag uacaugcagu gcagucucua aaggauaccu cagugccuua      240

cgcacaggau gguacacauc aguaauaaca aucgaacuuu caaacauaaa agaaaacaaa      300

ugcaauggaa ccgacgccaa aguaaaacua aucaaacaag aacuagacaa auauaaaaau      360

gcaguaacag aauuacaacu ccuaaugcaa uccacaccag caacaaauaa cagagcaaga      420

cgagaacucc cucgauucau gaauuacaca uuaaacaacg caaaaaaaac uaacguaacu      480

uuaucaaaaa aaagaaaacg uagauuucua ggauuccuac uaggcguagg guccgccauu      540

gcaucaggag uagcaguuag caaaguauua cauuuagaag gagaaguaaa uaaaaucaaa      600

agcgcacuac ucucaaccaa caaagcagua guaucacucu caaacggagu aucaguacua      660

acauccaaag uacucgaccu caaaaacuac auagacaaac aauuacuacc cauaguaaac      720

aaacaaucau gcucuauauc aaauaucgaa acaguaaucg aauuucaaca aaaaaacaau      780

cgacuacuug aaauaacaag agaguucucc gucaaugccg gagucaccac accagucuca      840

acauacaugc uaaccaacuc ugaacuccua ucacuaauaa augacaugcc aauaacaaac      900

gaccaaaaaa aacuaauguc aaauaacgua caaauaguac gacaacaaag uuauuccaua      960

augaguauaa ucaaagaaga aguguuagca uacguagucc aacuaccauu auauggagua     1020

auagacacac cauguuggaa auuacacacc ucaccacucu gcacuaccaa uacaaaagaa     1080

ggcucaaaua uaugccuaac ucgcacagac agaggcuggu acugcgauaa cgcaggaucc     1140

guaucuuucu uuccccaagc agaaacuugc aaaguacaau caaacagagu cuucugcgac     1200

accaugaaua gucucacauu accaucugaa guaaaccuau guaacguaga uauauucaau     1260

ccaaaauacg acugcaaaau aaugacauca aaaaccgacg ucucuagcag uguaaucaca     1320

ucacuaggag caauaguaag cugcuaugga aaaacaaaau guacagcauc aaacaaaaac     1380

aggggaauaa uaaaaaccuu cucaaacgga ugugacuacg uaucaaauaa aggcguagac     1440

acaguaagcg uaggaaacac ccuauacuac guuaacaaac aagaagggaa aucauuauac     1500

guaaaaggag aaccaauaau aaacuucuac gauccacucg uauucccauc cgacgaauuu     1560

gacgccagca uaucccaagu uaacgaaaaa auaaaccaau cacuugcauu uauacgaaaa     1620

ucugaugaac uucuccacaa cguaaaugca ggaaaaucca ccaccaauau aaugaucaca     1680

acuaucauca uaguaauaau cgucauuuua cuaucauuaa uagcaguugg ccuacuucua     1740

uacugcaaag caagauaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  789
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  789
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagcc      120

aacgcgauca ccaccauccu aacggcaguc accuucugcu ucgcaucagg ccaaaacauc      180

acagaagagu ucuaccaaag cacaugcucc gccguaucca aaggcuaccu cagcgcccua      240

cgcacaggcu gguacacauc ugucaucacc auagaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cugacgccaa aguaaagcug aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuccaacu acucaugcaa uccaccccug caaccaacaa cagggcccgc      420

cgcgaacucc cccgcuucau gaacuacacu uuaaacaacg ccaaaaagac caacgucaca      480

cucagcaaga aacggaaacg acgauuccua ggguuucucc uaggcgucgg cucggcaauc      540

gccuccggcg ucgccguaag caaaguacua caccuagaag gcgaagugaa caaaaucaaa      600

agugcccuuc ucuccaccaa caaggccgua gucucucuau ccaacggagu cucaguccuc      660

accucaaagg uccucgaccu caaaaacuac aucgacaaac aacuacuccc cauugucaac      720

aagcagucau gcuccauauc aaacaucgaa accgucaucg aguuccaaca gaaaaacaac      780

cgacuccucg aaauaaccag agaguucucg gucaacgccg gcgucaccac cccagucagc      840

accuacaugc ucacuaacuc cgaacuccua ucccucauca acgacaugcc aauuaccaac      900

gaccaaaaga aacuaauguc gaacaacguu caaaucgucc gacaacaaag uuacuccauc      960

augagcauaa ucaaagaaga aguucuagcg uacgucgucc aacucccacu auacggcguc     1020

aucgacacuc cgugcuggaa acuccacaca ucaccccuau guacaaccaa cacaaaagaa     1080

ggcagcaaca ucugccucac ccgcaccgac cgaggguggu auugcgauaa cgcuggcagc     1140

gucuccuucu ucccccaagc cgaaaccugc aaaguccaau caaacagagu auucugcgac     1200

accaugaacu cccuuacucu cccuagcgaa gucaaccucu gcaacguuga cauauucaac     1260

cccaaauacg acugcaaaau caugaccucc aagaccgacg ucuccuccuc cgucaucaca     1320

ucucuaggug ccauugucuc cugcuacgga aaaaccaaau gcacagccuc caacaaaaac     1380

cgcggcauca uaaaaaccuu cuccaacggc ugcgacuacg ucaguaauaa aggcgucgac     1440

acgguauccg uugggaauac gcuuuacuac guaaauaaac aagaaggcaa aucccucuac     1500

gucaaaggug aacccaucau aaacuucuac gacccgcuug uguucccauc cgacgaguuc     1560

gacgccagca ucagccaggu caacgaaaag aucaaccaau cccuagccuu cauccgcaaa     1620

agcgacgaac uacuacacaa cgucaacgcc ggaaaaucca caaccaacau caugaucacc     1680

accaucauca ucgucaucau cguaauccua cucucucuca ucgccgucgg ccuccuacug     1740

uacuguaaag cccgauaggg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  790
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  790
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aguugcuaau ccucaaagca      120

aaugcaauua ccacaauccu cacugcaguc acauuuuguu uugcuucugg ucaaaacauc      180

acugaagaau uuuaucaauc aacaugcagu gcaguuagca aaggcuaucu uagugcucug      240

agaacugguu gguauaccag uguuauaacu auagaauuaa guaauaucaa ggaaaauaag      300

uguaauggaa cagaugcuaa gguaaaauug auaaaacaag aauuagauaa auauaaaaau      360

gcuguaacag aauugcaguu gcucaugcaa agcacaccag caacaaacaa ucgagccaga      420

agagaacuac caagguuuau gaauuauaca cucaacaaug ccaaaaaaac caauguaaca      480

uuaagcaaga aaaggaaaag aagauuucuu gguuuuuugu uagguguugg aucugcaauc      540

gccaguggcg uugcuguauc uaagguccug caccuagaag gggaagugaa caagaucaaa      600

agugcucuac uauccacaaa caaggcugua gucagcuuau caaauggagu uagugucuua      660

accagcaaag uguuagaccu caaaaacuau auagauaaac aauuguuacc uauugugaac      720

aagcaaagcu gcagcauauc aaauauagaa acugugauag aguuccaaca aaagaacaac      780

agacuacuag agauuaccag ggaauuuagu guuaaugcag guguaacuac accuguaagc      840

acuuacaugu uaacuaauag ugaauuauug ucauuaauca augauaugcc uauaacaaau      900

gaucagaaaa aguuaauguc caacaauguu caaauaguua gacagcaaag uuacucuauc      960

auguccauaa uaaaagagga agucuuagca uauguaguac aauuaccacu auaugguguu     1020

auagauacac ccuguuggaa acuacacaca uccccucuau guacaaccaa cacaaaagaa     1080

ggguccaaca ucuguuuaac aagaacugac agaggauggu acugugacaa ugcaggauca     1140

guaucuuucu ucccacaagc ugaaacaugu aaaguucaau caaaucgagu auuuugugac     1200

acaaugaaca guuuaacauu accaagugaa guaaaucucu gcaauguuga cauauucaac     1260

cccaaauaug auuguaaaau uaugacuuca aaaacagaug uaagcagcuc cguuaucaca     1320

ucucuaggag ccauuguguc augcuauggc aaaacuaaau guacagcauc caauaaaaau     1380

cguggaauca uaaagacauu uucuaacggg ugcgauuaug uaucaaauaa agggguggac     1440

acugugucug uagguaacac auuauauuau guaaauaagc aagaagguaa aagucucuau     1500

guaaaaggug aaccaauaau aaauuucuau gacccauuag uauuccccuc ugaugaauuu     1560

gaugcaucaa uaucucaagu caacgagaag auuaaccaga gccuagcauu uauucguaaa     1620

uccgaugaau uauuacauaa uguaaaugcu gguaaaucca ccacaaauau caugauaacu     1680

acuauaauua uagugauuau aguaauauug uuaucauuaa uugcuguugg acugcucuua     1740

uacuguaagg ccagauaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  791
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  791
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcagc gccgucucca agggguaccu cagcgcccug      240

cggacgggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  792
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  792
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccguguc caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuccaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc caucgucaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cgccuccugg agaucacccg ggaguucagc gugaacgcgg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc caucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc gccagcaguc cuacagcauc      960

auguccauca ucaaggagga ggugcuggcc uacguggucc agcugccgcu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcggaccgac cgcggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccccaggc cgagaccugc aaggugcaga gcaaccgggu guucugcgac     1200

accaugaacu cccugacgcu gccgagcgag gucaaccucu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgucaucacc     1320

ucccuggggg ccaucgugag cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1440

accguguccg uggggaacac ccuguacuac gucaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccccugg uguucccguc cgacgaguuc     1560

gacgccagca ucucccaggu caacgagaag aucaaccaga gccuggccuu cauccggaag     1620

uccgacgagc uccugcacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgucauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cgcgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  793
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  793
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucuc caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuccaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc caucgucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

auguccauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  794
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  794
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuag uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

uccgcguugc ugucuacaaa uaaagcagug guaagccuau ccaacggggu uucagugcuc      660

acuucuaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aaucgugaac      720

aaacagagcu guucuauuuc caacaucgaa accgugauag aguuccagca gaagaauaac      780

cggcuccugg agauuacacg cgaauuuuca gucaaugccg gaguuaccac gccggugagc      840

acuuacaugu uaacaaacag ugagcugcuc ucucuuauca augacaugcc cauuaccaac      900

gaucaaaaga aacugauguc caauaacgua cagaucguga gacagcagag cuauucgauc      960

augucuauua uaaaggaaga ggucuuggcu uacgugguuc aacuaccucu guacggcgug     1020

aucgacacuc caugcuggaa acuccauaca uccccacugu guaccacgaa uaccaaggaa     1080

ggcucaaaca uuugccuuac aaggacugau cggggguggu auugugacaa ugccggaagu     1140

gucagcuucu uuccucaggc agagaccugc aaagugcagu ccaaccgcgu auucugugau     1200

acaaugaaua gucugacuuu gccaagcgag guuaaccucu gcaaugugga caucuuuaac     1260

cccaaguacg auuguaagau aaugaccuca aaaacagacg ucaguuccag cgugauuacc     1320

ucucugggug cuaucgucuc augcuauggc aagacuaaau gcacggccag uaacaagaau     1380

cgagggauca uuaaaacauu cagcaacgga ugugauuacg uguccaauaa gggcguugac     1440

accgugucug uagguaacac uuuauauuac gucaauaagc aagaagggaa aucgcuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuag uuuucccgag cgaugaauuu     1560

gacgcgucca uaucacaggu gaaugagaaa aucaaccaga gucucgccuu cauuagaaag     1620

ucugaugaac ugcuucacaa ugucaacgca ggcaaaagca ccacaaauau caugaucacc     1680

acuauuauaa ucgugauuau cguaauuuug cugucccuca ucgcuguggg ccugcuucug     1740

uacugcaagg ccaggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  795
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  795
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugag caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accagcaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc caucgugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augagcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  796
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  796
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugag caagguccuu caccuggaag gagaggugaa caaaaucaag      600

ucugcccucc uguccacgaa uaaagcuguu gugagccugu cuaacggcgu cuccgugcuc      660

acaagcaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gaucgucaac      720

aaacagucuu guuccauuag caacaucgaa accguuauug aguuccagca gaagaauaac      780

cgccugcuug agaucacaag agaauuuucc gugaaugccg gcgugaccac ccccgucucu      840

acauacaugc ugacgaacag cgagcuccug ucccugauca augacaugcc uauuaccaac      900

gaucaaaaga aacucaugag caauaacgug cagaucguuc ggcagcaguc uuauuccauu      960

augagcauca uuaaggaaga ggugcuggcg uacgucgugc aacuuccccu guacgggguu     1020

aucgacacac cuugcuggaa acuccauacc ucuccccugu guacaaccaa uacgaaggaa     1080

ggaagcaaca ucugccuuac acgcaccgau agaggcuggu auugugacaa ugccgggucc     1140

gugucuuucu uuccucaggc ugagaccugc aaaguccaga gcaaccgggu guucugugau     1200

acaaugaacu cccugacccu cccgagcgag gucaaucugu gcaaugugga cauuuuuaac     1260

cccaaguacg auuguaagau caugacaucu aaaacggacg uuuccagcuc ugugauuacc     1320

ucccugggag ccaucgucag cugcuauggc aagacaaaau gcaccgcuuc caacaagaau     1380

cgcgggauua ucaaaacauu cucuaacgga ugugauuacg ugagcaauaa gggcguugac     1440

accguguccg ucggcaacac gcucuauuac gugaauaagc aagaagggaa aucucuguau     1500

gugaagggag agccuaucau uaacuuuuac gacccccuug uuuucccuag cgaugaauuu     1560

gacgccucca ucagccaggu caaugagaaa auuaaccagu cucuggccuu caucagaaag     1620

uccgaugaac uccugcacaa ugugaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgucauucug cuuucucuca ucgcgguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  797
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  797
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau acucaaagcc      120

aacgcaauaa caacaauacu aacagcagua acauucugcu ucgcaucagg acaaaacauc      180

acagaagaau uuuaccaaag uacaugcagu gcagucucua aaggauaccu cagugccuua      240

cgcacaggau gguacacauc aguaauaaca aucgaacuuu caaacauaaa agaaaacaaa      300

ugcaauggaa ccgacgccaa aguaaaacua aucaaacaag aacuagacaa auauaaaaau      360

gcaguaacag aauuacaacu ccuaaugcaa uccacaccag caacaaauaa cagagcaaga      420

cgagaacucc cucgauucau gaauuacaca uuaaacaacg caaaaaaaac uaacguaacu      480

uuaucaaaaa aaagaaaacg uagauuucua ggauuccuac uaggcguagg guccgccauu      540

gcaucaggag uagcaguuag caaaguauua cauuuagaag gagaaguaaa uaaaaucaaa      600

agcgcacuac ucucaaccaa caaagcagua guaucacucu caaacggagu aucaguacua      660

acauccaaag uacucgaccu caaaaacuac auagacaaac aauuacuacc cauaguaaac      720

aaacaaucau gcucuauauc aaauaucgaa acaguaaucg aauuucaaca aaaaaacaau      780

cgacuacuug aaauaacaag agaguucucc gucaaugccg gagucaccac accagucuca      840

acauacaugc uaaccaacuc ugaacuccua ucacuaauaa augacaugcc aauaacaaac      900

gaccaaaaaa aacuaauguc aaauaacgua caaauaguac gacaacaaag uuauuccaua      960

augaguauaa ucaaagaaga aguguuagca uacguagucc aacuaccauu auauggagua     1020

auagacacac cauguuggaa auuacacacc ucaccacucu gcacuaccaa uacaaaagaa     1080

ggcucaaaua uaugccuaac ucgcacagac agaggcuggu acugcgauaa cgcaggaucc     1140

guaucuuucu uuccccaagc agaaacuugc aaaguacaau caaacagagu cuucugcgac     1200

accaugaaua gucucacauu accaucugaa guaaaccuau guaacguaga uauauucaau     1260

ccaaaauacg acugcaaaau aaugacauca aaaaccgacg ucucuagcag uguaaucaca     1320

ucacuaggag caauaguaag cugcuaugga aaaacaaaau guacagcauc aaacaaaaac     1380

aggggaauaa uaaaaaccuu cucaaacgga ugugacuacg uaucaaauaa aggcguagac     1440

acaguaagcg uaggaaacac ccuauacuac guuaacaaac aagaagggaa aucauuauac     1500

guaaaaggag aaccaauaau aaacuucuac gauccacucg uauucccauc cgacgaauuu     1560

gacgccagca uaucccaagu uaacgaaaaa auaaaccaau cacuugcauu uauacgaaaa     1620

ucugaugaac uucuccacaa cguaaaugca ggaaaaucca ccaccaauau aaugaucaca     1680

acuaucauca uaguaauaau cgucauuuua cuaucauuaa uagcaguugg ccuacuucua     1740

uacugcaaag caagauaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  798
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  798
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagcc      120

aacgcgauca ccaccauccu aacggcaguc accuucugcu ucgcaucagg ccaaaacauc      180

acagaagagu ucuaccaaag cacaugcucc gccguaucca aaggcuaccu cagcgcccua      240

cgcacaggcu gguacacauc ugucaucacc auagaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cugacgccaa aguaaagcug aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuccaacu acucaugcaa uccaccccug caaccaacaa cagggcccgc      420

cgcgaacucc cccgcuucau gaacuacacu uuaaacaacg ccaaaaagac caacgucaca      480

cucagcaaga aacggaaacg acgauuccua ggguuucucc uaggcgucgg cucggcaauc      540

gccuccggcg ucgccguaag caaaguacua caccuagaag gcgaagugaa caaaaucaaa      600

agugcccuuc ucuccaccaa caaggccgua gucucucuau ccaacggagu cucaguccuc      660

accucaaagg uccucgaccu caaaaacuac aucgacaaac aacuacuccc cauugucaac      720

aagcagucau gcuccauauc aaacaucgaa accgucaucg aguuccaaca gaaaaacaac      780

cgacuccucg aaauaaccag agaguucucg gucaacgccg gcgucaccac cccagucagc      840

accuacaugc ucacuaacuc cgaacuccua ucccucauca acgacaugcc aauuaccaac      900

gaccaaaaga aacuaauguc gaacaacguu caaaucgucc gacaacaaag uuacuccauc      960

augagcauaa ucaaagaaga aguucuagcg uacgucgucc aacucccacu auacggcguc     1020

aucgacacuc cgugcuggaa acuccacaca ucaccccuau guacaaccaa cacaaaagaa     1080

ggcagcaaca ucugccucac ccgcaccgac cgaggguggu auugcgauaa cgcuggcagc     1140

gucuccuucu ucccccaagc cgaaaccugc aaaguccaau caaacagagu auucugcgac     1200

accaugaacu cccuuacucu cccuagcgaa gucaaccucu gcaacguuga cauauucaac     1260

cccaaauacg acugcaaaau caugaccucc aagaccgacg ucuccuccuc cgucaucaca     1320

ucucuaggug ccauugucuc cugcuacgga aaaaccaaau gcacagccuc caacaaaaac     1380

cgcggcauca uaaaaaccuu cuccaacggc ugcgacuacg ucaguaauaa aggcgucgac     1440

acgguauccg uugggaauac gcuuuacuac guaaauaaac aagaaggcaa aucccucuac     1500

gucaaaggug aacccaucau aaacuucuac gacccgcuug uguucccauc cgacgaguuc     1560

gacgccagca ucagccaggu caacgaaaag aucaaccaau cccuagccuu cauccgcaaa     1620

agcgacgaac uacuacacaa cgucaacgcc ggaaaaucca caaccaacau caugaucacc     1680

accaucauca ucgucaucau cguaauccua cucucucuca ucgccgucgg ccuccuacug     1740

uacuguaaag cccgauaggg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  799
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  799
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagu ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca      180

uuuuguuuug cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca      240

guuagcaaag gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua      300

gaauuaagua auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua      360

aaacaagaau uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc      420

acaccagcaa caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc      480

aacaaugcca aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu      540

uuuuuguuag guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac      600

cuagaagggg aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc      660

agcuuaucaa auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua      720

gauaaacaau uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu      780

gugauagagu uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu      840

aaugcaggug uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca      900

uuaaucaaug auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa      960

auaguuagac agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau     1020

guaguacaau uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc     1080

ccucuaugua caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga     1140

ggaugguacu gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa     1200

guucaaucaa aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua     1260

aaucucugca auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa     1320

acagauguaa gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa     1380

acuaaaugua cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc     1440

gauuauguau caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua     1500

aauaagcaag aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac     1560

ccauuaguau uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu     1620

aaccagagcc uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu     1680

aaauccacca caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua     1740

ucauuaauug cuguuggacu gcucuuauac uguaaggcca gauaaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  800
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  800
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  801
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  801
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug      840

aacgcggggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccgcc agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac     1020

gugguccagc ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag     1200

gugcagagca accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc     1260

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc     1620

aaccagagcc uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggcgc gcugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  802
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  802
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  803
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  803
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua      660

agccuaucca acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc      780

gugauagagu uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc      840

aaugccggag uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu      900

cuuaucaaug acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag      960

aucgugagac agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac     1020

gugguucaac uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc     1080

ccacugugua ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa     1200

gugcagucca accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu     1260

aaccucugca auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa     1320

acagacguca guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag     1380

acuaaaugca cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu     1440

gauuacgugu ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc     1500

aauaagcaag aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuaguuu ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc     1620

aaccagaguc ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc     1680

aaaagcacca caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug     1740

ucccucaucg cugugggccu gcuucuguac ugcaaggcca ggugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  804
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  804
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  805
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  805
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug      660

agccugucua acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc      780

guuauugagu uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug      840

aaugccggcg ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc      900

cugaucaaug acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag      960

aucguucggc agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac     1020

gucgugcaac uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu     1080

ccccugugua caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga     1140

ggcugguauu gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa     1200

guccagagca accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc     1260

aaucugugca auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa     1320

acggacguuu ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag     1380

acaaaaugca ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu     1440

gauuacguga gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug     1500

aauaagcaag aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac     1560

ccccuuguuu ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu     1620

aaccagucuc uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu     1740

ucucucaucg cgguggggcu gcugcucuac ugcaaggccc ggugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  806
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  806
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauacu caaagccaac gcaauaacaa caauacuaac agcaguaaca      180

uucugcuucg caucaggaca aaacaucaca gaagaauuuu accaaaguac augcagugca      240

gucucuaaag gauaccucag ugccuuacgc acaggauggu acacaucagu aauaacaauc      300

gaacuuucaa acauaaaaga aaacaaaugc aauggaaccg acgccaaagu aaaacuaauc      360

aaacaagaac uagacaaaua uaaaaaugca guaacagaau uacaacuccu aaugcaaucc      420

acaccagcaa caaauaacag agcaagacga gaacucccuc gauucaugaa uuacacauua      480

aacaacgcaa aaaaaacuaa cguaacuuua ucaaaaaaaa gaaaacguag auuucuagga      540

uuccuacuag gcguaggguc cgccauugca ucaggaguag caguuagcaa aguauuacau      600

uuagaaggag aaguaaauaa aaucaaaagc gcacuacucu caaccaacaa agcaguagua      660

ucacucucaa acggaguauc aguacuaaca uccaaaguac ucgaccucaa aaacuacaua      720

gacaaacaau uacuacccau aguaaacaaa caaucaugcu cuauaucaaa uaucgaaaca      780

guaaucgaau uucaacaaaa aaacaaucga cuacuugaaa uaacaagaga guucuccguc      840

aaugccggag ucaccacacc agucucaaca uacaugcuaa ccaacucuga acuccuauca      900

cuaauaaaug acaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      960

auaguacgac aacaaaguua uuccauaaug aguauaauca aagaagaagu guuagcauac     1020

guaguccaac uaccauuaua uggaguaaua gacacaccau guuggaaauu acacaccuca     1080

ccacucugca cuaccaauac aaaagaaggc ucaaauauau gccuaacucg cacagacaga     1140

ggcugguacu gcgauaacgc aggauccgua ucuuucuuuc cccaagcaga aacuugcaaa     1200

guacaaucaa acagagucuu cugcgacacc augaauaguc ucacauuacc aucugaagua     1260

aaccuaugua acguagauau auucaaucca aaauacgacu gcaaaauaau gacaucaaaa     1320

accgacgucu cuagcagugu aaucacauca cuaggagcaa uaguaagcug cuauggaaaa     1380

acaaaaugua cagcaucaaa caaaaacagg ggaauaauaa aaaccuucuc aaacggaugu     1440

gacuacguau caaauaaagg cguagacaca guaagcguag gaaacacccu auacuacguu     1500

aacaaacaag aagggaaauc auuauacgua aaaggagaac caauaauaaa cuucuacgau     1560

ccacucguau ucccauccga cgaauuugac gccagcauau cccaaguuaa cgaaaaaaua     1620

aaccaaucac uugcauuuau acgaaaaucu gaugaacuuc uccacaacgu aaaugcagga     1680

aaauccacca ccaauauaau gaucacaacu aucaucauag uaauaaucgu cauuuuacua     1740

ucauuaauag caguuggccu acuucuauac ugcaaagcaa gauaaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  807
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  807
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagccaac gcgaucacca ccauccuaac ggcagucacc      180

uucugcuucg caucaggcca aaacaucaca gaagaguucu accaaagcac augcuccgcc      240

guauccaaag gcuaccucag cgcccuacgc acaggcuggu acacaucugu caucaccaua      300

gaacucucca acaucaaaga aaacaaaugc aacggcacug acgccaaagu aaagcugauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uccaacuacu caugcaaucc      420

accccugcaa ccaacaacag ggcccgccgc gaacuccccc gcuucaugaa cuacacuuua      480

aacaacgcca aaaagaccaa cgucacacuc agcaagaaac ggaaacgacg auuccuaggg      540

uuucuccuag gcgucggcuc ggcaaucgcc uccggcgucg ccguaagcaa aguacuacac      600

cuagaaggcg aagugaacaa aaucaaaagu gcccuucucu ccaccaacaa ggccguaguc      660

ucucuaucca acggagucuc aguccucacc ucaaaggucc ucgaccucaa aaacuacauc      720

gacaaacaac uacuccccau ugucaacaag cagucaugcu ccauaucaaa caucgaaacc      780

gucaucgagu uccaacagaa aaacaaccga cuccucgaaa uaaccagaga guucucgguc      840

aacgccggcg ucaccacccc agucagcacc uacaugcuca cuaacuccga acuccuaucc      900

cucaucaacg acaugccaau uaccaacgac caaaagaaac uaaugucgaa caacguucaa      960

aucguccgac aacaaaguua cuccaucaug agcauaauca aagaagaagu ucuagcguac     1020

gucguccaac ucccacuaua cggcgucauc gacacuccgu gcuggaaacu ccacacauca     1080

ccccuaugua caaccaacac aaaagaaggc agcaacaucu gccucacccg caccgaccga     1140

gggugguauu gcgauaacgc uggcagcguc uccuucuucc cccaagccga aaccugcaaa     1200

guccaaucaa acagaguauu cugcgacacc augaacuccc uuacucuccc uagcgaaguc     1260

aaccucugca acguugacau auucaacccc aaauacgacu gcaaaaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucacaucu cuaggugcca uugucuccug cuacggaaaa     1380

accaaaugca cagccuccaa caaaaaccgc ggcaucauaa aaaccuucuc caacggcugc     1440

gacuacguca guaauaaagg cgucgacacg guauccguug ggaauacgcu uuacuacgua     1500

aauaaacaag aaggcaaauc ccucuacguc aaaggugaac ccaucauaaa cuucuacgac     1560

ccgcuugugu ucccauccga cgaguucgac gccagcauca gccaggucaa cgaaaagauc     1620

aaccaauccc uagccuucau ccgcaaaagc gacgaacuac uacacaacgu caacgccgga     1680

aaauccacaa ccaacaucau gaucaccacc aucaucaucg ucaucaucgu aauccuacuc     1740

ucucucaucg ccgucggccu ccuacuguac uguaaagccc gauagggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  808
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  808
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  809
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  809
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  810
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  810
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  811
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  811
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  812
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  812
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccaggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  813
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  813
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  814
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  814
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  815
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  815
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauacucaaa      120

gccaacgcaa uaacaacaau acuaacagca guaacauucu gcuucgcauc aggacaaaac      180

aucacagaag aauuuuacca aaguacaugc agugcagucu cuaaaggaua ccucagugcc      240

uuacgcacag gaugguacac aucaguaaua acaaucgaac uuucaaacau aaaagaaaac      300

aaaugcaaug gaaccgacgc caaaguaaaa cuaaucaaac aagaacuaga caaauauaaa      360

aaugcaguaa cagaauuaca acuccuaaug caauccacac cagcaacaaa uaacagagca      420

agacgagaac ucccucgauu caugaauuac acauuaaaca acgcaaaaaa aacuaacgua      480

acuuuaucaa aaaaaagaaa acguagauuu cuaggauucc uacuaggcgu aggguccgcc      540

auugcaucag gaguagcagu uagcaaagua uuacauuuag aaggagaagu aaauaaaauc      600

aaaagcgcac uacucucaac caacaaagca guaguaucac ucucaaacgg aguaucagua      660

cuaacaucca aaguacucga ccucaaaaac uacauagaca aacaauuacu acccauagua      720

aacaaacaau caugcucuau aucaaauauc gaaacaguaa ucgaauuuca acaaaaaaac      780

aaucgacuac uugaaauaac aagagaguuc uccgucaaug ccggagucac cacaccaguc      840

ucaacauaca ugcuaaccaa cucugaacuc cuaucacuaa uaaaugacau gccaauaaca      900

aacgaccaaa aaaaacuaau gucaaauaac guacaaauag uacgacaaca aaguuauucc      960

auaaugagua uaaucaaaga agaaguguua gcauacguag uccaacuacc auuauaugga     1020

guaauagaca caccauguug gaaauuacac accucaccac ucugcacuac caauacaaaa     1080

gaaggcucaa auauaugccu aacucgcaca gacagaggcu gguacugcga uaacgcagga     1140

uccguaucuu ucuuucccca agcagaaacu ugcaaaguac aaucaaacag agucuucugc     1200

gacaccauga auagucucac auuaccaucu gaaguaaacc uauguaacgu agauauauuc     1260

aauccaaaau acgacugcaa aauaaugaca ucaaaaaccg acgucucuag caguguaauc     1320

acaucacuag gagcaauagu aagcugcuau ggaaaaacaa aauguacagc aucaaacaaa     1380

aacaggggaa uaauaaaaac cuucucaaac ggaugugacu acguaucaaa uaaaggcgua     1440

gacacaguaa gcguaggaaa cacccuauac uacguuaaca aacaagaagg gaaaucauua     1500

uacguaaaag gagaaccaau aauaaacuuc uacgauccac ucguauuccc auccgacgaa     1560

uuugacgcca gcauauccca aguuaacgaa aaaauaaacc aaucacuugc auuuauacga     1620

aaaucugaug aacuucucca caacguaaau gcaggaaaau ccaccaccaa uauaaugauc     1680

acaacuauca ucauaguaau aaucgucauu uuacuaucau uaauagcagu uggccuacuu     1740

cuauacugca aagcaagaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  816
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  816
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gccaacgcga ucaccaccau ccuaacggca gucaccuucu gcuucgcauc aggccaaaac      180

aucacagaag aguucuacca aagcacaugc uccgccguau ccaaaggcua ccucagcgcc      240

cuacgcacag gcugguacac aucugucauc accauagaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacugacgc caaaguaaag cugaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacucca acuacucaug caauccaccc cugcaaccaa caacagggcc      420

cgccgcgaac ucccccgcuu caugaacuac acuuuaaaca acgccaaaaa gaccaacguc      480

acacucagca agaaacggaa acgacgauuc cuaggguuuc uccuaggcgu cggcucggca      540

aucgccuccg gcgucgccgu aagcaaagua cuacaccuag aaggcgaagu gaacaaaauc      600

aaaagugccc uucucuccac caacaaggcc guagucucuc uauccaacgg agucucaguc      660

cucaccucaa agguccucga ccucaaaaac uacaucgaca aacaacuacu ccccauuguc      720

aacaagcagu caugcuccau aucaaacauc gaaaccguca ucgaguucca acagaaaaac      780

aaccgacucc ucgaaauaac cagagaguuc ucggucaacg ccggcgucac caccccaguc      840

agcaccuaca ugcucacuaa cuccgaacuc cuaucccuca ucaacgacau gccaauuacc      900

aacgaccaaa agaaacuaau gucgaacaac guucaaaucg uccgacaaca aaguuacucc      960

aucaugagca uaaucaaaga agaaguucua gcguacgucg uccaacuccc acuauacggc     1020

gucaucgaca cuccgugcug gaaacuccac acaucacccc uauguacaac caacacaaaa     1080

gaaggcagca acaucugccu cacccgcacc gaccgagggu gguauugcga uaacgcuggc     1140

agcgucuccu ucuuccccca agccgaaacc ugcaaagucc aaucaaacag aguauucugc     1200

gacaccauga acucccuuac ucucccuagc gaagucaacc ucugcaacgu ugacauauuc     1260

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

acaucucuag gugccauugu cuccugcuac ggaaaaacca aaugcacagc cuccaacaaa     1380

aaccgcggca ucauaaaaac cuucuccaac ggcugcgacu acgucaguaa uaaaggcguc     1440

gacacgguau ccguugggaa uacgcuuuac uacguaaaua aacaagaagg caaaucccuc     1500

uacgucaaag gugaacccau cauaaacuuc uacgacccgc uuguguuccc auccgacgag     1560

uucgacgcca gcaucagcca ggucaacgaa aagaucaacc aaucccuagc cuucauccgc     1620

aaaagcgacg aacuacuaca caacgucaac gccggaaaau ccacaaccaa caucaugauc     1680

accaccauca ucaucgucau caucguaauc cuacucucuc ucaucgccgu cggccuccua     1740

cuguacugua aagcccgaua gggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  817
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  817
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  818
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  818
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  819
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  819
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  820
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  820
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  821
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  821
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccaggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  822
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  822
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  823
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  823
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  824
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  824
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauacucaaa      120

gccaacgcaa uaacaacaau acuaacagca guaacauucu gcuucgcauc aggacaaaac      180

aucacagaag aauuuuacca aaguacaugc agugcagucu cuaaaggaua ccucagugcc      240

uuacgcacag gaugguacac aucaguaaua acaaucgaac uuucaaacau aaaagaaaac      300

aaaugcaaug gaaccgacgc caaaguaaaa cuaaucaaac aagaacuaga caaauauaaa      360

aaugcaguaa cagaauuaca acuccuaaug caauccacac cagcaacaaa uaacagagca      420

agacgagaac ucccucgauu caugaauuac acauuaaaca acgcaaaaaa aacuaacgua      480

acuuuaucaa aaaaaagaaa acguagauuu cuaggauucc uacuaggcgu aggguccgcc      540

auugcaucag gaguagcagu uagcaaagua uuacauuuag aaggagaagu aaauaaaauc      600

aaaagcgcac uacucucaac caacaaagca guaguaucac ucucaaacgg aguaucagua      660

cuaacaucca aaguacucga ccucaaaaac uacauagaca aacaauuacu acccauagua      720

aacaaacaau caugcucuau aucaaauauc gaaacaguaa ucgaauuuca acaaaaaaac      780

aaucgacuac uugaaauaac aagagaguuc uccgucaaug ccggagucac cacaccaguc      840

ucaacauaca ugcuaaccaa cucugaacuc cuaucacuaa uaaaugacau gccaauaaca      900

aacgaccaaa aaaaacuaau gucaaauaac guacaaauag uacgacaaca aaguuauucc      960

auaaugagua uaaucaaaga agaaguguua gcauacguag uccaacuacc auuauaugga     1020

guaauagaca caccauguug gaaauuacac accucaccac ucugcacuac caauacaaaa     1080

gaaggcucaa auauaugccu aacucgcaca gacagaggcu gguacugcga uaacgcagga     1140

uccguaucuu ucuuucccca agcagaaacu ugcaaaguac aaucaaacag agucuucugc     1200

gacaccauga auagucucac auuaccaucu gaaguaaacc uauguaacgu agauauauuc     1260

aauccaaaau acgacugcaa aauaaugaca ucaaaaaccg acgucucuag caguguaauc     1320

acaucacuag gagcaauagu aagcugcuau ggaaaaacaa aauguacagc aucaaacaaa     1380

aacaggggaa uaauaaaaac cuucucaaac ggaugugacu acguaucaaa uaaaggcgua     1440

gacacaguaa gcguaggaaa cacccuauac uacguuaaca aacaagaagg gaaaucauua     1500

uacguaaaag gagaaccaau aauaaacuuc uacgauccac ucguauuccc auccgacgaa     1560

uuugacgcca gcauauccca aguuaacgaa aaaauaaacc aaucacuugc auuuauacga     1620

aaaucugaug aacuucucca caacguaaau gcaggaaaau ccaccaccaa uauaaugauc     1680

acaacuauca ucauaguaau aaucgucauu uuacuaucau uaauagcagu uggccuacuu     1740

cuauacugca aagcaagaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  825
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  825
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gccaacgcga ucaccaccau ccuaacggca gucaccuucu gcuucgcauc aggccaaaac      180

aucacagaag aguucuacca aagcacaugc uccgccguau ccaaaggcua ccucagcgcc      240

cuacgcacag gcugguacac aucugucauc accauagaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacugacgc caaaguaaag cugaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacucca acuacucaug caauccaccc cugcaaccaa caacagggcc      420

cgccgcgaac ucccccgcuu caugaacuac acuuuaaaca acgccaaaaa gaccaacguc      480

acacucagca agaaacggaa acgacgauuc cuaggguuuc uccuaggcgu cggcucggca      540

aucgccuccg gcgucgccgu aagcaaagua cuacaccuag aaggcgaagu gaacaaaauc      600

aaaagugccc uucucuccac caacaaggcc guagucucuc uauccaacgg agucucaguc      660

cucaccucaa agguccucga ccucaaaaac uacaucgaca aacaacuacu ccccauuguc      720

aacaagcagu caugcuccau aucaaacauc gaaaccguca ucgaguucca acagaaaaac      780

aaccgacucc ucgaaauaac cagagaguuc ucggucaacg ccggcgucac caccccaguc      840

agcaccuaca ugcucacuaa cuccgaacuc cuaucccuca ucaacgacau gccaauuacc      900

aacgaccaaa agaaacuaau gucgaacaac guucaaaucg uccgacaaca aaguuacucc      960

aucaugagca uaaucaaaga agaaguucua gcguacgucg uccaacuccc acuauacggc     1020

gucaucgaca cuccgugcug gaaacuccac acaucacccc uauguacaac caacacaaaa     1080

gaaggcagca acaucugccu cacccgcacc gaccgagggu gguauugcga uaacgcuggc     1140

agcgucuccu ucuuccccca agccgaaacc ugcaaagucc aaucaaacag aguauucugc     1200

gacaccauga acucccuuac ucucccuagc gaagucaacc ucugcaacgu ugacauauuc     1260

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

acaucucuag gugccauugu cuccugcuac ggaaaaacca aaugcacagc cuccaacaaa     1380

aaccgcggca ucauaaaaac cuucuccaac ggcugcgacu acgucaguaa uaaaggcguc     1440

gacacgguau ccguugggaa uacgcuuuac uacguaaaua aacaagaagg caaaucccuc     1500

uacgucaaag gugaacccau cauaaacuuc uacgacccgc uuguguuccc auccgacgag     1560

uucgacgcca gcaucagcca ggucaacgaa aagaucaacc aaucccuagc cuucauccgc     1620

aaaagcgacg aacuacuaca caacgucaac gccggaaaau ccacaaccaa caucaugauc     1680

accaccauca ucaucgucau caucguaauc cuacucucuc ucaucgccgu cggccuccua     1740

cuguacugua aagcccgaua gggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  826
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  826
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  827
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  827
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  828
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  828
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  829
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  829
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  830
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  830
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccaggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  831
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  831
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  832
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  832
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  833
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  833
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauacucaaa      120

gccaacgcaa uaacaacaau acuaacagca guaacauucu gcuucgcauc aggacaaaac      180

aucacagaag aauuuuacca aaguacaugc agugcagucu cuaaaggaua ccucagugcc      240

uuacgcacag gaugguacac aucaguaaua acaaucgaac uuucaaacau aaaagaaaac      300

aaaugcaaug gaaccgacgc caaaguaaaa cuaaucaaac aagaacuaga caaauauaaa      360

aaugcaguaa cagaauuaca acuccuaaug caauccacac cagcaacaaa uaacagagca      420

agacgagaac ucccucgauu caugaauuac acauuaaaca acgcaaaaaa aacuaacgua      480

acuuuaucaa aaaaaagaaa acguagauuu cuaggauucc uacuaggcgu aggguccgcc      540

auugcaucag gaguagcagu uagcaaagua uuacauuuag aaggagaagu aaauaaaauc      600

aaaagcgcac uacucucaac caacaaagca guaguaucac ucucaaacgg aguaucagua      660

cuaacaucca aaguacucga ccucaaaaac uacauagaca aacaauuacu acccauagua      720

aacaaacaau caugcucuau aucaaauauc gaaacaguaa ucgaauuuca acaaaaaaac      780

aaucgacuac uugaaauaac aagagaguuc uccgucaaug ccggagucac cacaccaguc      840

ucaacauaca ugcuaaccaa cucugaacuc cuaucacuaa uaaaugacau gccaauaaca      900

aacgaccaaa aaaaacuaau gucaaauaac guacaaauag uacgacaaca aaguuauucc      960

auaaugagua uaaucaaaga agaaguguua gcauacguag uccaacuacc auuauaugga     1020

guaauagaca caccauguug gaaauuacac accucaccac ucugcacuac caauacaaaa     1080

gaaggcucaa auauaugccu aacucgcaca gacagaggcu gguacugcga uaacgcagga     1140

uccguaucuu ucuuucccca agcagaaacu ugcaaaguac aaucaaacag agucuucugc     1200

gacaccauga auagucucac auuaccaucu gaaguaaacc uauguaacgu agauauauuc     1260

aauccaaaau acgacugcaa aauaaugaca ucaaaaaccg acgucucuag caguguaauc     1320

acaucacuag gagcaauagu aagcugcuau ggaaaaacaa aauguacagc aucaaacaaa     1380

aacaggggaa uaauaaaaac cuucucaaac ggaugugacu acguaucaaa uaaaggcgua     1440

gacacaguaa gcguaggaaa cacccuauac uacguuaaca aacaagaagg gaaaucauua     1500

uacguaaaag gagaaccaau aauaaacuuc uacgauccac ucguauuccc auccgacgaa     1560

uuugacgcca gcauauccca aguuaacgaa aaaauaaacc aaucacuugc auuuauacga     1620

aaaucugaug aacuucucca caacguaaau gcaggaaaau ccaccaccaa uauaaugauc     1680

acaacuauca ucauaguaau aaucgucauu uuacuaucau uaauagcagu uggccuacuu     1740

cuauacugca aagcaagaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  834
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  834
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gccaacgcga ucaccaccau ccuaacggca gucaccuucu gcuucgcauc aggccaaaac      180

aucacagaag aguucuacca aagcacaugc uccgccguau ccaaaggcua ccucagcgcc      240

cuacgcacag gcugguacac aucugucauc accauagaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacugacgc caaaguaaag cugaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacucca acuacucaug caauccaccc cugcaaccaa caacagggcc      420

cgccgcgaac ucccccgcuu caugaacuac acuuuaaaca acgccaaaaa gaccaacguc      480

acacucagca agaaacggaa acgacgauuc cuaggguuuc uccuaggcgu cggcucggca      540

aucgccuccg gcgucgccgu aagcaaagua cuacaccuag aaggcgaagu gaacaaaauc      600

aaaagugccc uucucuccac caacaaggcc guagucucuc uauccaacgg agucucaguc      660

cucaccucaa agguccucga ccucaaaaac uacaucgaca aacaacuacu ccccauuguc      720

aacaagcagu caugcuccau aucaaacauc gaaaccguca ucgaguucca acagaaaaac      780

aaccgacucc ucgaaauaac cagagaguuc ucggucaacg ccggcgucac caccccaguc      840

agcaccuaca ugcucacuaa cuccgaacuc cuaucccuca ucaacgacau gccaauuacc      900

aacgaccaaa agaaacuaau gucgaacaac guucaaaucg uccgacaaca aaguuacucc      960

aucaugagca uaaucaaaga agaaguucua gcguacgucg uccaacuccc acuauacggc     1020

gucaucgaca cuccgugcug gaaacuccac acaucacccc uauguacaac caacacaaaa     1080

gaaggcagca acaucugccu cacccgcacc gaccgagggu gguauugcga uaacgcuggc     1140

agcgucuccu ucuuccccca agccgaaacc ugcaaagucc aaucaaacag aguauucugc     1200

gacaccauga acucccuuac ucucccuagc gaagucaacc ucugcaacgu ugacauauuc     1260

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

acaucucuag gugccauugu cuccugcuac ggaaaaacca aaugcacagc cuccaacaaa     1380

aaccgcggca ucauaaaaac cuucuccaac ggcugcgacu acgucaguaa uaaaggcguc     1440

gacacgguau ccguugggaa uacgcuuuac uacguaaaua aacaagaagg caaaucccuc     1500

uacgucaaag gugaacccau cauaaacuuc uacgacccgc uuguguuccc auccgacgag     1560

uucgacgcca gcaucagcca ggucaacgaa aagaucaacc aaucccuagc cuucauccgc     1620

aaaagcgacg aacuacuaca caacgucaac gccggaaaau ccacaaccaa caucaugauc     1680

accaccauca ucaucgucau caucguaauc cuacucucuc ucaucgccgu cggccuccua     1740

cuguacugua aagcccgaua gggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  835
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  835
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaguugcu aauccucaaa      120

gcaaaugcaa uuaccacaau ccucacugca gucacauuuu guuuugcuuc uggucaaaac      180

aucacugaag aauuuuauca aucaacaugc agugcaguua gcaaaggcua ucuuagugcu      240

cugagaacug guugguauac caguguuaua acuauagaau uaaguaauau caaggaaaau      300

aaguguaaug gaacagaugc uaagguaaaa uugauaaaac aagaauuaga uaaauauaaa      360

aaugcuguaa cagaauugca guugcucaug caaagcacac cagcaacaaa caaucgagcc      420

agaagagaac uaccaagguu uaugaauuau acacucaaca augccaaaaa aaccaaugua      480

acauuaagca agaaaaggaa aagaagauuu cuugguuuuu uguuaggugu uggaucugca      540

aucgccagug gcguugcugu aucuaagguc cugcaccuag aaggggaagu gaacaagauc      600

aaaagugcuc uacuauccac aaacaaggcu guagucagcu uaucaaaugg aguuaguguc      660

uuaaccagca aaguguuaga ccucaaaaac uauauagaua aacaauuguu accuauugug      720

aacaagcaaa gcugcagcau aucaaauaua gaaacuguga uagaguucca acaaaagaac      780

aacagacuac uagagauuac cagggaauuu aguguuaaug cagguguaac uacaccugua      840

agcacuuaca uguuaacuaa uagugaauua uugucauuaa ucaaugauau gccuauaaca      900

aaugaucaga aaaaguuaau guccaacaau guucaaauag uuagacagca aaguuacucu      960

aucaugucca uaauaaaaga ggaagucuua gcauauguag uacaauuacc acuauauggu     1020

guuauagaua cacccuguug gaaacuacac acauccccuc uauguacaac caacacaaaa     1080

gaagggucca acaucuguuu aacaagaacu gacagaggau gguacuguga caaugcagga     1140

ucaguaucuu ucuucccaca agcugaaaca uguaaaguuc aaucaaaucg aguauuuugu     1200

gacacaauga acaguuuaac auuaccaagu gaaguaaauc ucugcaaugu ugacauauuc     1260

aaccccaaau augauuguaa aauuaugacu ucaaaaacag auguaagcag cuccguuauc     1320

acaucucuag gagccauugu gucaugcuau ggcaaaacua aauguacagc auccaauaaa     1380

aaucguggaa ucauaaagac auuuucuaac gggugcgauu auguaucaaa uaaaggggug     1440

gacacugugu cuguagguaa cacauuauau uauguaaaua agcaagaagg uaaaagucuc     1500

uauguaaaag gugaaccaau aauaaauuuc uaugacccau uaguauuccc cucugaugaa     1560

uuugaugcau caauaucuca agucaacgag aagauuaacc agagccuagc auuuauucgu     1620

aaauccgaug aauuauuaca uaauguaaau gcugguaaau ccaccacaaa uaucaugaua     1680

acuacuauaa uuauagugau uauaguaaua uuguuaucau uaauugcugu uggacugcuc     1740

uuauacugua aggccagaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  836
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  836
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccaccugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggacgg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  837
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  837
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu guccaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccucca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccaucguc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccgccucc uggagaucac ccgggaguuc agcgugaacg cgggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccgccagca guccuacagc      960

aucaugucca ucaucaagga ggaggugcug gccuacgugg uccagcugcc gcucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

agcgucuccu ucuuccccca ggccgagacc ugcaaggugc agagcaaccg gguguucugc     1200

gacaccauga acucccugac gcugccgagc gaggucaacc ucugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgucauc     1320

accucccugg gggccaucgu gagcugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1440

gacaccgugu ccguggggaa cacccuguac uacgucaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc guccgacgag     1560

uucgacgcca gcaucuccca ggucaacgag aagaucaacc agagccuggc cuucauccgg     1620

aaguccgacg agcuccugca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgucauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcgcgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  838
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  838
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cuccaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccucca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccaucguc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugucca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  839
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  839
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uaguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aaguccgcgu ugcugucuac aaauaaagca gugguaagcc uauccaacgg gguuucagug      660

cucacuucua agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaaucgug      720

aacaaacaga gcuguucuau uuccaacauc gaaaccguga uagaguucca gcagaagaau      780

aaccggcucc uggagauuac acgcgaauuu ucagucaaug ccggaguuac cacgccggug      840

agcacuuaca uguuaacaaa cagugagcug cucucucuua ucaaugacau gcccauuacc      900

aacgaucaaa agaaacugau guccaauaac guacagaucg ugagacagca gagcuauucg      960

aucaugucua uuauaaagga agaggucuug gcuuacgugg uucaacuacc ucuguacggc     1020

gugaucgaca cuccaugcug gaaacuccau acauccccac uguguaccac gaauaccaag     1080

gaaggcucaa acauuugccu uacaaggacu gaucgggggu gguauuguga caaugccgga     1140

agugucagcu ucuuuccuca ggcagagacc ugcaaagugc aguccaaccg cguauucugu     1200

gauacaauga auagucugac uuugccaagc gagguuaacc ucugcaaugu ggacaucuuu     1260

aaccccaagu acgauuguaa gauaaugacc ucaaaaacag acgucaguuc cagcgugauu     1320

accucucugg gugcuaucgu cucaugcuau ggcaagacua aaugcacggc caguaacaag     1380

aaucgaggga ucauuaaaac auucagcaac ggaugugauu acguguccaa uaagggcguu     1440

gacaccgugu cuguagguaa cacuuuauau uacgucaaua agcaagaagg gaaaucgcug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uaguuuuccc gagcgaugaa     1560

uuugacgcgu ccauaucaca ggugaaugag aaaaucaacc agagucucgc cuucauuaga     1620

aagucugaug aacugcuuca caaugucaac gcaggcaaaa gcaccacaaa uaucaugauc     1680

accacuauua uaaucgugau uaucguaauu uugcuguccc ucaucgcugu gggccugcuu     1740

cuguacugca aggccaggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  840
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  840
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gagcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccagca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccaucgug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugagca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  841
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  841
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu gagcaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagucugccc uccuguccac gaauaaagcu guugugagcc ugucuaacgg cgucuccgug      660

cucacaagca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgaucguc      720

aacaaacagu cuuguuccau uagcaacauc gaaaccguua uugaguucca gcagaagaau      780

aaccgccugc uugagaucac aagagaauuu uccgugaaug ccggcgugac cacccccguc      840

ucuacauaca ugcugacgaa cagcgagcuc cugucccuga ucaaugacau gccuauuacc      900

aacgaucaaa agaaacucau gagcaauaac gugcagaucg uucggcagca gucuuauucc      960

auuaugagca ucauuaagga agaggugcug gcguacgucg ugcaacuucc ccuguacggg     1020

guuaucgaca caccuugcug gaaacuccau accucucccc uguguacaac caauacgaag     1080

gaaggaagca acaucugccu uacacgcacc gauagaggcu gguauuguga caaugccggg     1140

uccgugucuu ucuuuccuca ggcugagacc ugcaaagucc agagcaaccg gguguucugu     1200

gauacaauga acucccugac ccucccgagc gaggucaauc ugugcaaugu ggacauuuuu     1260

aaccccaagu acgauuguaa gaucaugaca ucuaaaacgg acguuuccag cucugugauu     1320

accucccugg gagccaucgu cagcugcuau ggcaagacaa aaugcaccgc uuccaacaag     1380

aaucgcggga uuaucaaaac auucucuaac ggaugugauu acgugagcaa uaagggcguu     1440

gacaccgugu ccgucggcaa cacgcucuau uacgugaaua agcaagaagg gaaaucucug     1500

uaugugaagg gagagccuau cauuaacuuu uacgaccccc uuguuuuccc uagcgaugaa     1560

uuugacgccu ccaucagcca ggucaaugag aaaauuaacc agucucuggc cuucaucaga     1620

aaguccgaug aacuccugca caaugugaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgucauu cugcuuucuc ucaucgcggu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  842
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  842
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauacucaaa      120

gccaacgcaa uaacaacaau acuaacagca guaacauucu gcuucgcauc aggacaaaac      180

aucacagaag aauuuuacca aaguacaugc agugcagucu cuaaaggaua ccucagugcc      240

uuacgcacag gaugguacac aucaguaaua acaaucgaac uuucaaacau aaaagaaaac      300

aaaugcaaug gaaccgacgc caaaguaaaa cuaaucaaac aagaacuaga caaauauaaa      360

aaugcaguaa cagaauuaca acuccuaaug caauccacac cagcaacaaa uaacagagca      420

agacgagaac ucccucgauu caugaauuac acauuaaaca acgcaaaaaa aacuaacgua      480

acuuuaucaa aaaaaagaaa acguagauuu cuaggauucc uacuaggcgu aggguccgcc      540

auugcaucag gaguagcagu uagcaaagua uuacauuuag aaggagaagu aaauaaaauc      600

aaaagcgcac uacucucaac caacaaagca guaguaucac ucucaaacgg aguaucagua      660

cuaacaucca aaguacucga ccucaaaaac uacauagaca aacaauuacu acccauagua      720

aacaaacaau caugcucuau aucaaauauc gaaacaguaa ucgaauuuca acaaaaaaac      780

aaucgacuac uugaaauaac aagagaguuc uccgucaaug ccggagucac cacaccaguc      840

ucaacauaca ugcuaaccaa cucugaacuc cuaucacuaa uaaaugacau gccaauaaca      900

aacgaccaaa aaaaacuaau gucaaauaac guacaaauag uacgacaaca aaguuauucc      960

auaaugagua uaaucaaaga agaaguguua gcauacguag uccaacuacc auuauaugga     1020

guaauagaca caccauguug gaaauuacac accucaccac ucugcacuac caauacaaaa     1080

gaaggcucaa auauaugccu aacucgcaca gacagaggcu gguacugcga uaacgcagga     1140

uccguaucuu ucuuucccca agcagaaacu ugcaaaguac aaucaaacag agucuucugc     1200

gacaccauga auagucucac auuaccaucu gaaguaaacc uauguaacgu agauauauuc     1260

aauccaaaau acgacugcaa aauaaugaca ucaaaaaccg acgucucuag caguguaauc     1320

acaucacuag gagcaauagu aagcugcuau ggaaaaacaa aauguacagc aucaaacaaa     1380

aacaggggaa uaauaaaaac cuucucaaac ggaugugacu acguaucaaa uaaaggcgua     1440

gacacaguaa gcguaggaaa cacccuauac uacguuaaca aacaagaagg gaaaucauua     1500

uacguaaaag gagaaccaau aauaaacuuc uacgauccac ucguauuccc auccgacgaa     1560

uuugacgcca gcauauccca aguuaacgaa aaaauaaacc aaucacuugc auuuauacga     1620

aaaucugaug aacuucucca caacguaaau gcaggaaaau ccaccaccaa uauaaugauc     1680

acaacuauca ucauaguaau aaucgucauu uuacuaucau uaauagcagu uggccuacuu     1740

cuauacugca aagcaagaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  843
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  843
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gccaacgcga ucaccaccau ccuaacggca gucaccuucu gcuucgcauc aggccaaaac      180

aucacagaag aguucuacca aagcacaugc uccgccguau ccaaaggcua ccucagcgcc      240

cuacgcacag gcugguacac aucugucauc accauagaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacugacgc caaaguaaag cugaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacucca acuacucaug caauccaccc cugcaaccaa caacagggcc      420

cgccgcgaac ucccccgcuu caugaacuac acuuuaaaca acgccaaaaa gaccaacguc      480

acacucagca agaaacggaa acgacgauuc cuaggguuuc uccuaggcgu cggcucggca      540

aucgccuccg gcgucgccgu aagcaaagua cuacaccuag aaggcgaagu gaacaaaauc      600

aaaagugccc uucucuccac caacaaggcc guagucucuc uauccaacgg agucucaguc      660

cucaccucaa agguccucga ccucaaaaac uacaucgaca aacaacuacu ccccauuguc      720

aacaagcagu caugcuccau aucaaacauc gaaaccguca ucgaguucca acagaaaaac      780

aaccgacucc ucgaaauaac cagagaguuc ucggucaacg ccggcgucac caccccaguc      840

agcaccuaca ugcucacuaa cuccgaacuc cuaucccuca ucaacgacau gccaauuacc      900

aacgaccaaa agaaacuaau gucgaacaac guucaaaucg uccgacaaca aaguuacucc      960

aucaugagca uaaucaaaga agaaguucua gcguacgucg uccaacuccc acuauacggc     1020

gucaucgaca cuccgugcug gaaacuccac acaucacccc uauguacaac caacacaaaa     1080

gaaggcagca acaucugccu cacccgcacc gaccgagggu gguauugcga uaacgcuggc     1140

agcgucuccu ucuuccccca agccgaaacc ugcaaagucc aaucaaacag aguauucugc     1200

gacaccauga acucccuuac ucucccuagc gaagucaacc ucugcaacgu ugacauauuc     1260

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

acaucucuag gugccauugu cuccugcuac ggaaaaacca aaugcacagc cuccaacaaa     1380

aaccgcggca ucauaaaaac cuucuccaac ggcugcgacu acgucaguaa uaaaggcguc     1440

gacacgguau ccguugggaa uacgcuuuac uacguaaaua aacaagaagg caaaucccuc     1500

uacgucaaag gugaacccau cauaaacuuc uacgacccgc uuguguuccc auccgacgag     1560

uucgacgcca gcaucagcca ggucaacgaa aagaucaacc aaucccuagc cuucauccgc     1620

aaaagcgacg aacuacuaca caacgucaac gccggaaaau ccacaaccaa caucaugauc     1680

accaccauca ucaucgucau caucguaauc cuacucucuc ucaucgccgu cggccuccua     1740

cuguacugua aagcccgaua gggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  844
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  844
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agauaaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  845
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  845
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  846
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  846
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  847
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  847
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  848
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  848
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  849
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  849
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  850
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  850
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cggugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  851
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  851
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaauac ucaaagccaa cgcaauaaca acaauacuaa cagcaguaac auucugcuuc      240

gcaucaggac aaaacaucac agaagaauuu uaccaaagua caugcagugc agucucuaaa      300

ggauaccuca gugccuuacg cacaggaugg uacacaucag uaauaacaau cgaacuuuca      360

aacauaaaag aaaacaaaug caauggaacc gacgccaaag uaaaacuaau caaacaagaa      420

cuagacaaau auaaaaaugc aguaacagaa uuacaacucc uaaugcaauc cacaccagca      480

acaaauaaca gagcaagacg agaacucccu cgauucauga auuacacauu aaacaacgca      540

aaaaaaacua acguaacuuu aucaaaaaaa agaaaacgua gauuucuagg auuccuacua      600

ggcguagggu ccgccauugc aucaggagua gcaguuagca aaguauuaca uuuagaagga      660

gaaguaaaua aaaucaaaag cgcacuacuc ucaaccaaca aagcaguagu aucacucuca      720

aacggaguau caguacuaac auccaaagua cucgaccuca aaaacuacau agacaaacaa      780

uuacuaccca uaguaaacaa acaaucaugc ucuauaucaa auaucgaaac aguaaucgaa      840

uuucaacaaa aaaacaaucg acuacuugaa auaacaagag aguucuccgu caaugccgga      900

gucaccacac cagucucaac auacaugcua accaacucug aacuccuauc acuaauaaau      960

gacaugccaa uaacaaacga ccaaaaaaaa cuaaugucaa auaacguaca aauaguacga     1020

caacaaaguu auuccauaau gaguauaauc aaagaagaag uguuagcaua cguaguccaa     1080

cuaccauuau auggaguaau agacacacca uguuggaaau uacacaccuc accacucugc     1140

acuaccaaua caaaagaagg cucaaauaua ugccuaacuc gcacagacag aggcugguac     1200

ugcgauaacg caggauccgu aucuuucuuu ccccaagcag aaacuugcaa aguacaauca     1260

aacagagucu ucugcgacac caugaauagu cucacauuac caucugaagu aaaccuaugu     1320

aacguagaua uauucaaucc aaaauacgac ugcaaaauaa ugacaucaaa aaccgacguc     1380

ucuagcagug uaaucacauc acuaggagca auaguaagcu gcuauggaaa aacaaaaugu     1440

acagcaucaa acaaaaacag gggaauaaua aaaaccuucu caaacggaug ugacuacgua     1500

ucaaauaaag gcguagacac aguaagcgua ggaaacaccc uauacuacgu uaacaaacaa     1560

gaagggaaau cauuauacgu aaaaggagaa ccaauaauaa acuucuacga uccacucgua     1620

uucccauccg acgaauuuga cgccagcaua ucccaaguua acgaaaaaau aaaccaauca     1680

cuugcauuua uacgaaaauc ugaugaacuu cuccacaacg uaaaugcagg aaaauccacc     1740

accaauauaa ugaucacaac uaucaucaua guaauaaucg ucauuuuacu aucauuaaua     1800

gcaguuggcc uacuucuaua cugcaaagca agauaaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  852
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  852
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagccaa cgcgaucacc accauccuaa cggcagucac cuucugcuuc      240

gcaucaggcc aaaacaucac agaagaguuc uaccaaagca caugcuccgc cguauccaaa      300

ggcuaccuca gcgcccuacg cacaggcugg uacacaucug ucaucaccau agaacucucc      360

aacaucaaag aaaacaaaug caacggcacu gacgccaaag uaaagcugau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuccaacuac ucaugcaauc caccccugca      480

accaacaaca gggcccgccg cgaacucccc cgcuucauga acuacacuuu aaacaacgcc      540

aaaaagacca acgucacacu cagcaagaaa cggaaacgac gauuccuagg guuucuccua      600

ggcgucggcu cggcaaucgc cuccggcguc gccguaagca aaguacuaca ccuagaaggc      660

gaagugaaca aaaucaaaag ugcccuucuc uccaccaaca aggccguagu cucucuaucc      720

aacggagucu caguccucac cucaaagguc cucgaccuca aaaacuacau cgacaaacaa      780

cuacucccca uugucaacaa gcagucaugc uccauaucaa acaucgaaac cgucaucgag      840

uuccaacaga aaaacaaccg acuccucgaa auaaccagag aguucucggu caacgccggc      900

gucaccaccc cagucagcac cuacaugcuc acuaacuccg aacuccuauc ccucaucaac      960

gacaugccaa uuaccaacga ccaaaagaaa cuaaugucga acaacguuca aaucguccga     1020

caacaaaguu acuccaucau gagcauaauc aaagaagaag uucuagcgua cgucguccaa     1080

cucccacuau acggcgucau cgacacuccg ugcuggaaac uccacacauc accccuaugu     1140

acaaccaaca caaaagaagg cagcaacauc ugccucaccc gcaccgaccg agggugguau     1200

ugcgauaacg cuggcagcgu cuccuucuuc ccccaagccg aaaccugcaa aguccaauca     1260

aacagaguau ucugcgacac caugaacucc cuuacucucc cuagcgaagu caaccucugc     1320

aacguugaca uauucaaccc caaauacgac ugcaaaauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucacauc ucuaggugcc auugucuccu gcuacggaaa aaccaaaugc     1440

acagccucca acaaaaaccg cggcaucaua aaaaccuucu ccaacggcug cgacuacguc     1500

aguaauaaag gcgucgacac gguauccguu gggaauacgc uuuacuacgu aaauaaacaa     1560

gaaggcaaau cccucuacgu caaaggugaa cccaucauaa acuucuacga cccgcuugug     1620

uucccauccg acgaguucga cgccagcauc agccagguca acgaaaagau caaccaaucc     1680

cuagccuuca uccgcaaaag cgacgaacua cuacacaacg ucaacgccgg aaaauccaca     1740

accaacauca ugaucaccac caucaucauc gucaucaucg uaauccuacu cucucucauc     1800

gccgucggcc uccuacugua cuguaaagcc cgauagggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  853
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  853
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agauaaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  854
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  854
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  855
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  855
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  856
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  856
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  857
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  857
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  858
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  858
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  859
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  859
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cggugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  860
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  860
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaauac ucaaagccaa cgcaauaaca acaauacuaa cagcaguaac auucugcuuc      240

gcaucaggac aaaacaucac agaagaauuu uaccaaagua caugcagugc agucucuaaa      300

ggauaccuca gugccuuacg cacaggaugg uacacaucag uaauaacaau cgaacuuuca      360

aacauaaaag aaaacaaaug caauggaacc gacgccaaag uaaaacuaau caaacaagaa      420

cuagacaaau auaaaaaugc aguaacagaa uuacaacucc uaaugcaauc cacaccagca      480

acaaauaaca gagcaagacg agaacucccu cgauucauga auuacacauu aaacaacgca      540

aaaaaaacua acguaacuuu aucaaaaaaa agaaaacgua gauuucuagg auuccuacua      600

ggcguagggu ccgccauugc aucaggagua gcaguuagca aaguauuaca uuuagaagga      660

gaaguaaaua aaaucaaaag cgcacuacuc ucaaccaaca aagcaguagu aucacucuca      720

aacggaguau caguacuaac auccaaagua cucgaccuca aaaacuacau agacaaacaa      780

uuacuaccca uaguaaacaa acaaucaugc ucuauaucaa auaucgaaac aguaaucgaa      840

uuucaacaaa aaaacaaucg acuacuugaa auaacaagag aguucuccgu caaugccgga      900

gucaccacac cagucucaac auacaugcua accaacucug aacuccuauc acuaauaaau      960

gacaugccaa uaacaaacga ccaaaaaaaa cuaaugucaa auaacguaca aauaguacga     1020

caacaaaguu auuccauaau gaguauaauc aaagaagaag uguuagcaua cguaguccaa     1080

cuaccauuau auggaguaau agacacacca uguuggaaau uacacaccuc accacucugc     1140

acuaccaaua caaaagaagg cucaaauaua ugccuaacuc gcacagacag aggcugguac     1200

ugcgauaacg caggauccgu aucuuucuuu ccccaagcag aaacuugcaa aguacaauca     1260

aacagagucu ucugcgacac caugaauagu cucacauuac caucugaagu aaaccuaugu     1320

aacguagaua uauucaaucc aaaauacgac ugcaaaauaa ugacaucaaa aaccgacguc     1380

ucuagcagug uaaucacauc acuaggagca auaguaagcu gcuauggaaa aacaaaaugu     1440

acagcaucaa acaaaaacag gggaauaaua aaaaccuucu caaacggaug ugacuacgua     1500

ucaaauaaag gcguagacac aguaagcgua ggaaacaccc uauacuacgu uaacaaacaa     1560

gaagggaaau cauuauacgu aaaaggagaa ccaauaauaa acuucuacga uccacucgua     1620

uucccauccg acgaauuuga cgccagcaua ucccaaguua acgaaaaaau aaaccaauca     1680

cuugcauuua uacgaaaauc ugaugaacuu cuccacaacg uaaaugcagg aaaauccacc     1740

accaauauaa ugaucacaac uaucaucaua guaauaaucg ucauuuuacu aucauuaaua     1800

gcaguuggcc uacuucuaua cugcaaagca agauaaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  861
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  861
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagccaa cgcgaucacc accauccuaa cggcagucac cuucugcuuc      240

gcaucaggcc aaaacaucac agaagaguuc uaccaaagca caugcuccgc cguauccaaa      300

ggcuaccuca gcgcccuacg cacaggcugg uacacaucug ucaucaccau agaacucucc      360

aacaucaaag aaaacaaaug caacggcacu gacgccaaag uaaagcugau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuccaacuac ucaugcaauc caccccugca      480

accaacaaca gggcccgccg cgaacucccc cgcuucauga acuacacuuu aaacaacgcc      540

aaaaagacca acgucacacu cagcaagaaa cggaaacgac gauuccuagg guuucuccua      600

ggcgucggcu cggcaaucgc cuccggcguc gccguaagca aaguacuaca ccuagaaggc      660

gaagugaaca aaaucaaaag ugcccuucuc uccaccaaca aggccguagu cucucuaucc      720

aacggagucu caguccucac cucaaagguc cucgaccuca aaaacuacau cgacaaacaa      780

cuacucccca uugucaacaa gcagucaugc uccauaucaa acaucgaaac cgucaucgag      840

uuccaacaga aaaacaaccg acuccucgaa auaaccagag aguucucggu caacgccggc      900

gucaccaccc cagucagcac cuacaugcuc acuaacuccg aacuccuauc ccucaucaac      960

gacaugccaa uuaccaacga ccaaaagaaa cuaaugucga acaacguuca aaucguccga     1020

caacaaaguu acuccaucau gagcauaauc aaagaagaag uucuagcgua cgucguccaa     1080

cucccacuau acggcgucau cgacacuccg ugcuggaaac uccacacauc accccuaugu     1140

acaaccaaca caaaagaagg cagcaacauc ugccucaccc gcaccgaccg agggugguau     1200

ugcgauaacg cuggcagcgu cuccuucuuc ccccaagccg aaaccugcaa aguccaauca     1260

aacagaguau ucugcgacac caugaacucc cuuacucucc cuagcgaagu caaccucugc     1320

aacguugaca uauucaaccc caaauacgac ugcaaaauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucacauc ucuaggugcc auugucuccu gcuacggaaa aaccaaaugc     1440

acagccucca acaaaaaccg cggcaucaua aaaaccuucu ccaacggcug cgacuacguc     1500

aguaauaaag gcgucgacac gguauccguu gggaauacgc uuuacuacgu aaauaaacaa     1560

gaaggcaaau cccucuacgu caaaggugaa cccaucauaa acuucuacga cccgcuugug     1620

uucccauccg acgaguucga cgccagcauc agccagguca acgaaaagau caaccaaucc     1680

cuagccuuca uccgcaaaag cgacgaacua cuacacaacg ucaacgccgg aaaauccaca     1740

accaacauca ugaucaccac caucaucauc gucaucaucg uaauccuacu cucucucauc     1800

gccgucggcc uccuacugua cuguaaagcc cgauagggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  862
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  862
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

uugcuaaucc ucaaagcaaa ugcaauuacc acaauccuca cugcagucac auuuuguuuu      240

gcuucugguc aaaacaucac ugaagaauuu uaucaaucaa caugcagugc aguuagcaaa      300

ggcuaucuua gugcucugag aacugguugg uauaccagug uuauaacuau agaauuaagu      360

aauaucaagg aaaauaagug uaauggaaca gaugcuaagg uaaaauugau aaaacaagaa      420

uuagauaaau auaaaaaugc uguaacagaa uugcaguugc ucaugcaaag cacaccagca      480

acaaacaauc gagccagaag agaacuacca agguuuauga auuauacacu caacaaugcc      540

aaaaaaacca auguaacauu aagcaagaaa aggaaaagaa gauuucuugg uuuuuuguua      600

gguguuggau cugcaaucgc caguggcguu gcuguaucua agguccugca ccuagaaggg      660

gaagugaaca agaucaaaag ugcucuacua uccacaaaca aggcuguagu cagcuuauca      720

aauggaguua gugucuuaac cagcaaagug uuagaccuca aaaacuauau agauaaacaa      780

uuguuaccua uugugaacaa gcaaagcugc agcauaucaa auauagaaac ugugauagag      840

uuccaacaaa agaacaacag acuacuagag auuaccaggg aauuuagugu uaaugcaggu      900

guaacuacac cuguaagcac uuacauguua acuaauagug aauuauuguc auuaaucaau      960

gauaugccua uaacaaauga ucagaaaaag uuaaugucca acaauguuca aauaguuaga     1020

cagcaaaguu acucuaucau guccauaaua aaagaggaag ucuuagcaua uguaguacaa     1080

uuaccacuau augguguuau agauacaccc uguuggaaac uacacacauc cccucuaugu     1140

acaaccaaca caaaagaagg guccaacauc uguuuaacaa gaacugacag aggaugguac     1200

ugugacaaug caggaucagu aucuuucuuc ccacaagcug aaacauguaa aguucaauca     1260

aaucgaguau uuugugacac aaugaacagu uuaacauuac caagugaagu aaaucucugc     1320

aauguugaca uauucaaccc caaauaugau uguaaaauua ugacuucaaa aacagaugua     1380

agcagcuccg uuaucacauc ucuaggagcc auugugucau gcuauggcaa aacuaaaugu     1440

acagcaucca auaaaaaucg uggaaucaua aagacauuuu cuaacgggug cgauuaugua     1500

ucaaauaaag ggguggacac ugugucugua gguaacacau uauauuaugu aaauaagcaa     1560

gaagguaaaa gucucuaugu aaaaggugaa ccaauaauaa auuucuauga cccauuagua     1620

uuccccucug augaauuuga ugcaucaaua ucucaaguca acgagaagau uaaccagagc     1680

cuagcauuua uucguaaauc cgaugaauua uuacauaaug uaaaugcugg uaaauccacc     1740

acaaauauca ugauaacuac uauaauuaua gugauuauag uaauauuguu aucauuaauu     1800

gcuguuggac ugcucuuaua cuguaaggcc agauaaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  863
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  863
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca ccugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gacgggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  864
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  864
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugucca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuccaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca ucgucaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg ccuccuggag aucacccggg aguucagcgu gaacgcgggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgc     1020

cagcaguccu acagcaucau guccaucauc aaggaggagg ugcuggccua cgugguccag     1080

cugccgcucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aaccgggugu ucugcgacac caugaacucc cugacgcugc cgagcgaggu caaccucugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ucaucaccuc ccugggggcc aucgugagcu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcgucgacac cguguccgug gggaacaccc uguacuacgu caacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccccuggug     1620

uucccguccg acgaguucga cgccagcauc ucccagguca acgagaagau caaccagagc     1680

cuggccuuca uccggaaguc cgacgagcuc cugcacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ucauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcg cgcugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  865
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  865
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucucca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuccaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca ucgucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau guccaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  866
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  866
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuagua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaaguc cgcguugcug ucuacaaaua aagcaguggu aagccuaucc      720

aacgggguuu cagugcucac uucuaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa ucgugaacaa acagagcugu ucuauuucca acaucgaaac cgugauagag      840

uuccagcaga agaauaaccg gcuccuggag auuacacgcg aauuuucagu caaugccgga      900

guuaccacgc cggugagcac uuacauguua acaaacagug agcugcucuc ucuuaucaau      960

gacaugccca uuaccaacga ucaaaagaaa cugaugucca auaacguaca gaucgugaga     1020

cagcagagcu auucgaucau gucuauuaua aaggaagagg ucuuggcuua cgugguucaa     1080

cuaccucugu acggcgugau cgacacucca ugcuggaaac uccauacauc cccacugugu     1140

accacgaaua ccaaggaagg cucaaacauu ugccuuacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaagugu cagcuucuuu ccucaggcag agaccugcaa agugcagucc     1260

aaccgcguau ucugugauac aaugaauagu cugacuuugc caagcgaggu uaaccucugc     1320

aauguggaca ucuuuaaccc caaguacgau uguaagauaa ugaccucaaa aacagacguc     1380

aguuccagcg ugauuaccuc ucugggugcu aucgucucau gcuauggcaa gacuaaaugc     1440

acggccagua acaagaaucg agggaucauu aaaacauuca gcaacggaug ugauuacgug     1500

uccaauaagg gcguugacac cgugucugua gguaacacuu uauauuacgu caauaagcaa     1560

gaagggaaau cgcuguaugu gaagggagag ccuaucauua acuuuuacga cccccuaguu     1620

uucccgagcg augaauuuga cgcguccaua ucacagguga augagaaaau caaccagagu     1680

cucgccuuca uuagaaaguc ugaugaacug cuucacaaug ucaacgcagg caaaagcacc     1740

acaaauauca ugaucaccac uauuauaauc gugauuaucg uaauuuugcu gucccucauc     1800

gcugugggcc ugcuucugua cugcaaggcc aggugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  867
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  867
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugagca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cagcaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca ucgugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gagcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  868
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  868
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugagca agguccuuca ccuggaagga      660

gaggugaaca aaaucaaguc ugcccuccug uccacgaaua aagcuguugu gagccugucu      720

aacggcgucu ccgugcucac aagcaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga ucgucaacaa acagucuugu uccauuagca acaucgaaac cguuauugag      840

uuccagcaga agaauaaccg ccugcuugag aucacaagag aauuuuccgu gaaugccggc      900

gugaccaccc ccgucucuac auacaugcug acgaacagcg agcuccuguc ccugaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cucaugagca auaacgugca gaucguucgg     1020

cagcagucuu auuccauuau gagcaucauu aaggaagagg ugcuggcgua cgucgugcaa     1080

cuuccccugu acgggguuau cgacacaccu ugcuggaaac uccauaccuc uccccugugu     1140

acaaccaaua cgaaggaagg aagcaacauc ugccuuacac gcaccgauag aggcugguau     1200

ugugacaaug ccggguccgu gucuuucuuu ccucaggcug agaccugcaa aguccagagc     1260

aaccgggugu ucugugauac aaugaacucc cugacccucc cgagcgaggu caaucugugc     1320

aauguggaca uuuuuaaccc caaguacgau uguaagauca ugacaucuaa aacggacguu     1380

uccagcucug ugauuaccuc ccugggagcc aucgucagcu gcuauggcaa gacaaaaugc     1440

accgcuucca acaagaaucg cgggauuauc aaaacauucu cuaacggaug ugauuacgug     1500

agcaauaagg gcguugacac cguguccguc ggcaacacgc ucuauuacgu gaauaagcaa     1560

gaagggaaau cucuguaugu gaagggagag ccuaucauua acuuuuacga cccccuuguu     1620

uucccuagcg augaauuuga cgccuccauc agccagguca augagaaaau uaaccagucu     1680

cuggccuuca ucagaaaguc cgaugaacuc cugcacaaug ugaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ucauucugcu uucucucauc     1800

gcgguggggc ugcugcucua cugcaaggcc cggugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  869
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  869
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaauac ucaaagccaa cgcaauaaca acaauacuaa cagcaguaac auucugcuuc      240

gcaucaggac aaaacaucac agaagaauuu uaccaaagua caugcagugc agucucuaaa      300

ggauaccuca gugccuuacg cacaggaugg uacacaucag uaauaacaau cgaacuuuca      360

aacauaaaag aaaacaaaug caauggaacc gacgccaaag uaaaacuaau caaacaagaa      420

cuagacaaau auaaaaaugc aguaacagaa uuacaacucc uaaugcaauc cacaccagca      480

acaaauaaca gagcaagacg agaacucccu cgauucauga auuacacauu aaacaacgca      540

aaaaaaacua acguaacuuu aucaaaaaaa agaaaacgua gauuucuagg auuccuacua      600

ggcguagggu ccgccauugc aucaggagua gcaguuagca aaguauuaca uuuagaagga      660

gaaguaaaua aaaucaaaag cgcacuacuc ucaaccaaca aagcaguagu aucacucuca      720

aacggaguau caguacuaac auccaaagua cucgaccuca aaaacuacau agacaaacaa      780

uuacuaccca uaguaaacaa acaaucaugc ucuauaucaa auaucgaaac aguaaucgaa      840

uuucaacaaa aaaacaaucg acuacuugaa auaacaagag aguucuccgu caaugccgga      900

gucaccacac cagucucaac auacaugcua accaacucug aacuccuauc acuaauaaau      960

gacaugccaa uaacaaacga ccaaaaaaaa cuaaugucaa auaacguaca aauaguacga     1020

caacaaaguu auuccauaau gaguauaauc aaagaagaag uguuagcaua cguaguccaa     1080

cuaccauuau auggaguaau agacacacca uguuggaaau uacacaccuc accacucugc     1140

acuaccaaua caaaagaagg cucaaauaua ugccuaacuc gcacagacag aggcugguac     1200

ugcgauaacg caggauccgu aucuuucuuu ccccaagcag aaacuugcaa aguacaauca     1260

aacagagucu ucugcgacac caugaauagu cucacauuac caucugaagu aaaccuaugu     1320

aacguagaua uauucaaucc aaaauacgac ugcaaaauaa ugacaucaaa aaccgacguc     1380

ucuagcagug uaaucacauc acuaggagca auaguaagcu gcuauggaaa aacaaaaugu     1440

acagcaucaa acaaaaacag gggaauaaua aaaaccuucu caaacggaug ugacuacgua     1500

ucaaauaaag gcguagacac aguaagcgua ggaaacaccc uauacuacgu uaacaaacaa     1560

gaagggaaau cauuauacgu aaaaggagaa ccaauaauaa acuucuacga uccacucgua     1620

uucccauccg acgaauuuga cgccagcaua ucccaaguua acgaaaaaau aaaccaauca     1680

cuugcauuua uacgaaaauc ugaugaacuu cuccacaacg uaaaugcagg aaaauccacc     1740

accaauauaa ugaucacaac uaucaucaua guaauaaucg ucauuuuacu aucauuaaua     1800

gcaguuggcc uacuucuaua cugcaaagca agauaaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  870
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  870
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagccaa cgcgaucacc accauccuaa cggcagucac cuucugcuuc      240

gcaucaggcc aaaacaucac agaagaguuc uaccaaagca caugcuccgc cguauccaaa      300

ggcuaccuca gcgcccuacg cacaggcugg uacacaucug ucaucaccau agaacucucc      360

aacaucaaag aaaacaaaug caacggcacu gacgccaaag uaaagcugau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuccaacuac ucaugcaauc caccccugca      480

accaacaaca gggcccgccg cgaacucccc cgcuucauga acuacacuuu aaacaacgcc      540

aaaaagacca acgucacacu cagcaagaaa cggaaacgac gauuccuagg guuucuccua      600

ggcgucggcu cggcaaucgc cuccggcguc gccguaagca aaguacuaca ccuagaaggc      660

gaagugaaca aaaucaaaag ugcccuucuc uccaccaaca aggccguagu cucucuaucc      720

aacggagucu caguccucac cucaaagguc cucgaccuca aaaacuacau cgacaaacaa      780

cuacucccca uugucaacaa gcagucaugc uccauaucaa acaucgaaac cgucaucgag      840

uuccaacaga aaaacaaccg acuccucgaa auaaccagag aguucucggu caacgccggc      900

gucaccaccc cagucagcac cuacaugcuc acuaacuccg aacuccuauc ccucaucaac      960

gacaugccaa uuaccaacga ccaaaagaaa cuaaugucga acaacguuca aaucguccga     1020

caacaaaguu acuccaucau gagcauaauc aaagaagaag uucuagcgua cgucguccaa     1080

cucccacuau acggcgucau cgacacuccg ugcuggaaac uccacacauc accccuaugu     1140

acaaccaaca caaaagaagg cagcaacauc ugccucaccc gcaccgaccg agggugguau     1200

ugcgauaacg cuggcagcgu cuccuucuuc ccccaagccg aaaccugcaa aguccaauca     1260

aacagaguau ucugcgacac caugaacucc cuuacucucc cuagcgaagu caaccucugc     1320

aacguugaca uauucaaccc caaauacgac ugcaaaauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucacauc ucuaggugcc auugucuccu gcuacggaaa aaccaaaugc     1440

acagccucca acaaaaaccg cggcaucaua aaaaccuucu ccaacggcug cgacuacguc     1500

aguaauaaag gcgucgacac gguauccguu gggaauacgc uuuacuacgu aaauaaacaa     1560

gaaggcaaau cccucuacgu caaaggugaa cccaucauaa acuucuacga cccgcuugug     1620

uucccauccg acgaguucga cgccagcauc agccagguca acgaaaagau caaccaaucc     1680

cuagccuuca uccgcaaaag cgacgaacua cuacacaacg ucaacgccgg aaaauccaca     1740

accaacauca ugaucaccac caucaucauc gucaucaucg uaauccuacu cucucucauc     1800

gccgucggcc uccuacugua cuguaaagcc cgauagggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  871
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  871
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaguugcuaa uccucaaagc aaaugcaauu accacaaucc ucacugcagu cacauuuugu      120

uuugcuucug gucaaaacau cacugaagaa uuuuaucaau caacaugcag ugcaguuagc      180

aaaggcuauc uuagugcucu gagaacuggu ugguauacca guguuauaac uauagaauua      240

aguaauauca aggaaaauaa guguaaugga acagaugcua agguaaaauu gauaaaacaa      300

gaauuagaua aauauaaaaa ugcuguaaca gaauugcagu ugcucaugca aagcacacca      360

gcaacaaaca aucgagccag aagagaacua ccaagguuua ugaauuauac acucaacaau      420

gccaaaaaaa ccaauguaac auuaagcaag aaaaggaaaa gaagauuucu ugguuuuuug      480

uuagguguug gaucugcaau cgccaguggc guugcuguau cuaagguccu gcaccuagaa      540

ggggaaguga acaagaucaa aagugcucua cuauccacaa acaaggcugu agucagcuua      600

ucaaauggag uuagugucuu aaccagcaaa guguuagacc ucaaaaacua uauagauaaa      660

caauuguuac cuauugugaa caagcaaagc ugcagcauau caaauauaga aacugugaua      720

gaguuccaac aaaagaacaa cagacuacua gagauuacca gggaauuuag uguuaaugca      780

gguguaacua caccuguaag cacuuacaug uuaacuaaua gugaauuauu gucauuaauc      840

aaugauaugc cuauaacaaa ugaucagaaa aaguuaaugu ccaacaaugu ucaaauaguu      900

agacagcaaa guuacucuau cauguccaua auaaaagagg aagucuuagc auauguagua      960

caauuaccac uauauggugu uauagauaca cccuguugga aacuacacac auccccucua     1020

uguacaacca acacaaaaga aggguccaac aucuguuuaa caagaacuga cagaggaugg     1080

uacugugaca augcaggauc aguaucuuuc uucccacaag cugaaacaug uaaaguucaa     1140

ucaaaucgag uauuuuguga cacaaugaac aguuuaacau uaccaaguga aguaaaucuc     1200

ugcaauguug acauauucaa ccccaaauau gauuguaaaa uuaugacuuc aaaaacagau     1260

guaagcagcu ccguuaucac aucucuagga gccauugugu caugcuaugg caaaacuaaa     1320

uguacagcau ccaauaaaaa ucguggaauc auaaagacau uuucuaacgg gugcgauuau     1380

guaucaaaua aaggggugga cacugugucu guagguaaca cauuauauua uguaaauaag     1440

caagaaggua aaagucucua uguaaaaggu gaaccaauaa uaaauuucua ugacccauua     1500

guauuccccu cugaugaauu ugaugcauca auaucucaag ucaacgagaa gauuaaccag     1560

agccuagcau uuauucguaa auccgaugaa uuauuacaua auguaaaugc ugguaaaucc     1620

accacaaaua ucaugauaac uacuauaauu auagugauua uaguaauauu guuaucauua     1680

auugcuguug gacugcucuu auacuguaag gccagauaag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  872
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  872
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccaccugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggacgggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  873
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  873
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu ccaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuccaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccaucgucaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccgccuccug gagaucaccc gggaguucag cgugaacgcg      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cgccagcagu ccuacagcau cauguccauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugccgc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccagg ccgagaccug caaggugcag     1140

agcaaccggg uguucugcga caccaugaac ucccugacgc ugccgagcga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgucaucac cucccugggg gccaucguga gcugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga caccgugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccgu ccgacgaguu cgacgccagc aucucccagg ucaacgagaa gaucaaccag     1560

agccuggccu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgucauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcgcgcugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  874
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  874
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu ccaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuccaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccaucgucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau cauguccauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  875
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  875
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguua guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa guccgcguug cugucuacaa auaaagcagu gguaagccua      600

uccaacgggg uuucagugcu cacuucuaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caaucgugaa caaacagagc uguucuauuu ccaacaucga aaccgugaua      720

gaguuccagc agaagaauaa ccggcuccug gagauuacac gcgaauuuuc agucaaugcc      780

ggaguuacca cgccggugag cacuuacaug uuaacaaaca gugagcugcu cucucuuauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaacugaugu ccaauaacgu acagaucgug      900

agacagcaga gcuauucgau caugucuauu auaaaggaag aggucuuggc uuacgugguu      960

caacuaccuc uguacggcgu gaucgacacu ccaugcugga aacuccauac auccccacug     1020

uguaccacga auaccaagga aggcucaaac auuugccuua caaggacuga ucgggggugg     1080

uauugugaca augccggaag ugucagcuuc uuuccucagg cagagaccug caaagugcag     1140

uccaaccgcg uauucuguga uacaaugaau agucugacuu ugccaagcga gguuaaccuc     1200

ugcaaugugg acaucuuuaa ccccaaguac gauuguaaga uaaugaccuc aaaaacagac     1260

gucaguucca gcgugauuac cucucugggu gcuaucgucu caugcuaugg caagacuaaa     1320

ugcacggcca guaacaagaa ucgagggauc auuaaaacau ucagcaacgg augugauuac     1380

guguccaaua agggcguuga caccgugucu guagguaaca cuuuauauua cgucaauaag     1440

caagaaggga aaucgcugua ugugaaggga gagccuauca uuaacuuuua cgacccccua     1500

guuuucccga gcgaugaauu ugacgcgucc auaucacagg ugaaugagaa aaucaaccag     1560

agucucgccu ucauuagaaa gucugaugaa cugcuucaca augucaacgc aggcaaaagc     1620

accacaaaua ucaugaucac cacuauuaua aucgugauua ucguaauuuu gcugucccuc     1680

aucgcugugg gccugcuucu guacugcaag gccaggugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  876
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  876
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccguga gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccagcaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccaucgugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugagcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  877
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  877
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcuguga gcaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gucugcccuc cuguccacga auaaagcugu ugugagccug      600

ucuaacggcg ucuccgugcu cacaagcaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgaucgucaa caaacagucu uguuccauua gcaacaucga aaccguuauu      720

gaguuccagc agaagaauaa ccgccugcuu gagaucacaa gagaauuuuc cgugaaugcc      780

ggcgugacca cccccgucuc uacauacaug cugacgaaca gcgagcuccu gucccugauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacucauga gcaauaacgu gcagaucguu      900

cggcagcagu cuuauuccau uaugagcauc auuaaggaag aggugcuggc guacgucgug      960

caacuucccc uguacggggu uaucgacaca ccuugcugga aacuccauac cucuccccug     1020

uguacaacca auacgaagga aggaagcaac aucugccuua cacgcaccga uagaggcugg     1080

uauugugaca augccggguc cgugucuuuc uuuccucagg cugagaccug caaaguccag     1140

agcaaccggg uguucuguga uacaaugaac ucccugaccc ucccgagcga ggucaaucug     1200

ugcaaugugg acauuuuuaa ccccaaguac gauuguaaga ucaugacauc uaaaacggac     1260

guuuccagcu cugugauuac cucccuggga gccaucguca gcugcuaugg caagacaaaa     1320

ugcaccgcuu ccaacaagaa ucgcgggauu aucaaaacau ucucuaacgg augugauuac     1380

gugagcaaua agggcguuga caccgugucc gucggcaaca cgcucuauua cgugaauaag     1440

caagaaggga aaucucugua ugugaaggga gagccuauca uuaacuuuua cgacccccuu     1500

guuuucccua gcgaugaauu ugacgccucc aucagccagg ucaaugagaa aauuaaccag     1560

ucucuggccu ucaucagaaa guccgaugaa cuccugcaca augugaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgucauucu gcuuucucuc     1680

aucgcggugg ggcugcugcu cuacugcaag gcccggugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  878
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  878
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaauuacuaa uacucaaagc caacgcaaua acaacaauac uaacagcagu aacauucugc      120

uucgcaucag gacaaaacau cacagaagaa uuuuaccaaa guacaugcag ugcagucucu      180

aaaggauacc ucagugccuu acgcacagga ugguacacau caguaauaac aaucgaacuu      240

ucaaacauaa aagaaaacaa augcaaugga accgacgcca aaguaaaacu aaucaaacaa      300

gaacuagaca aauauaaaaa ugcaguaaca gaauuacaac uccuaaugca auccacacca      360

gcaacaaaua acagagcaag acgagaacuc ccucgauuca ugaauuacac auuaaacaac      420

gcaaaaaaaa cuaacguaac uuuaucaaaa aaaagaaaac guagauuucu aggauuccua      480

cuaggcguag gguccgccau ugcaucagga guagcaguua gcaaaguauu acauuuagaa      540

ggagaaguaa auaaaaucaa aagcgcacua cucucaacca acaaagcagu aguaucacuc      600

ucaaacggag uaucaguacu aacauccaaa guacucgacc ucaaaaacua cauagacaaa      660

caauuacuac ccauaguaaa caaacaauca ugcucuauau caaauaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ucgacuacuu gaaauaacaa gagaguucuc cgucaaugcc      780

ggagucacca caccagucuc aacauacaug cuaaccaacu cugaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu acaaauagua      900

cgacaacaaa guuauuccau aaugaguaua aucaaagaag aaguguuagc auacguaguc      960

caacuaccau uauauggagu aauagacaca ccauguugga aauuacacac cucaccacuc     1020

ugcacuacca auacaaaaga aggcucaaau auaugccuaa cucgcacaga cagaggcugg     1080

uacugcgaua acgcaggauc cguaucuuuc uuuccccaag cagaaacuug caaaguacaa     1140

ucaaacagag ucuucugcga caccaugaau agucucacau uaccaucuga aguaaaccua     1200

uguaacguag auauauucaa uccaaaauac gacugcaaaa uaaugacauc aaaaaccgac     1260

gucucuagca guguaaucac aucacuagga gcaauaguaa gcugcuaugg aaaaacaaaa     1320

uguacagcau caaacaaaaa caggggaaua auaaaaaccu ucucaaacgg augugacuac     1380

guaucaaaua aaggcguaga cacaguaagc guaggaaaca cccuauacua cguuaacaaa     1440

caagaaggga aaucauuaua cguaaaagga gaaccaauaa uaaacuucua cgauccacuc     1500

guauucccau ccgacgaauu ugacgccagc auaucccaag uuaacgaaaa aauaaaccaa     1560

ucacuugcau uuauacgaaa aucugaugaa cuucuccaca acguaaaugc aggaaaaucc     1620

accaccaaua uaaugaucac aacuaucauc auaguaauaa ucgucauuuu acuaucauua     1680

auagcaguug gccuacuucu auacugcaaa gcaagauaag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  879
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  879
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuaa uccuaaaagc caacgcgauc accaccaucc uaacggcagu caccuucugc      120

uucgcaucag gccaaaacau cacagaagag uucuaccaaa gcacaugcuc cgccguaucc      180

aaaggcuacc ucagcgcccu acgcacaggc ugguacacau cugucaucac cauagaacuc      240

uccaacauca aagaaaacaa augcaacggc acugacgcca aaguaaagcu gaucaaacaa      300

gaacucgaca aauacaaaaa cgcagucacc gaacuccaac uacucaugca auccaccccu      360

gcaaccaaca acagggcccg ccgcgaacuc ccccgcuuca ugaacuacac uuuaaacaac      420

gccaaaaaga ccaacgucac acucagcaag aaacggaaac gacgauuccu aggguuucuc      480

cuaggcgucg gcucggcaau cgccuccggc gucgccguaa gcaaaguacu acaccuagaa      540

ggcgaaguga acaaaaucaa aagugcccuu cucuccacca acaaggccgu agucucucua      600

uccaacggag ucucaguccu caccucaaag guccucgacc ucaaaaacua caucgacaaa      660

caacuacucc ccauugucaa caagcaguca ugcuccauau caaacaucga aaccgucauc      720

gaguuccaac agaaaaacaa ccgacuccuc gaaauaacca gagaguucuc ggucaacgcc      780

ggcgucacca ccccagucag caccuacaug cucacuaacu ccgaacuccu aucccucauc      840

aacgacaugc caauuaccaa cgaccaaaag aaacuaaugu cgaacaacgu ucaaaucguc      900

cgacaacaaa guuacuccau caugagcaua aucaaagaag aaguucuagc guacgucguc      960

caacucccac uauacggcgu caucgacacu ccgugcugga aacuccacac aucaccccua     1020

uguacaacca acacaaaaga aggcagcaac aucugccuca cccgcaccga ccgagggugg     1080

uauugcgaua acgcuggcag cgucuccuuc uucccccaag ccgaaaccug caaaguccaa     1140

ucaaacagag uauucugcga caccaugaac ucccuuacuc ucccuagcga agucaaccuc     1200

ugcaacguug acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac aucucuaggu gccauugucu ccugcuacgg aaaaaccaaa     1320

ugcacagccu ccaacaaaaa ccgcggcauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucaguaaua aaggcgucga cacgguaucc guugggaaua cgcuuuacua cguaaauaaa     1440

caagaaggca aaucccucua cgucaaaggu gaacccauca uaaacuucua cgacccgcuu     1500

guguucccau ccgacgaguu cgacgccagc aucagccagg ucaacgaaaa gaucaaccaa     1560

ucccuagccu ucauccgcaa aagcgacgaa cuacuacaca acgucaacgc cggaaaaucc     1620

acaaccaaca ucaugaucac caccaucauc aucgucauca ucguaauccu acucucucuc     1680

aucgccgucg gccuccuacu guacuguaaa gcccgauagg gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  880
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  880
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagu       60

ugcuaauccu caaagcaaau gcaauuacca caauccucac ugcagucaca uuuuguuuug      120

cuucugguca aaacaucacu gaagaauuuu aucaaucaac augcagugca guuagcaaag      180

gcuaucuuag ugcucugaga acugguuggu auaccagugu uauaacuaua gaauuaagua      240

auaucaagga aaauaagugu aauggaacag augcuaaggu aaaauugaua aaacaagaau      300

uagauaaaua uaaaaaugcu guaacagaau ugcaguugcu caugcaaagc acaccagcaa      360

caaacaaucg agccagaaga gaacuaccaa gguuuaugaa uuauacacuc aacaaugcca      420

aaaaaaccaa uguaacauua agcaagaaaa ggaaaagaag auuucuuggu uuuuuguuag      480

guguuggauc ugcaaucgcc aguggcguug cuguaucuaa gguccugcac cuagaagggg      540

aagugaacaa gaucaaaagu gcucuacuau ccacaaacaa ggcuguaguc agcuuaucaa      600

auggaguuag ugucuuaacc agcaaagugu uagaccucaa aaacuauaua gauaaacaau      660

uguuaccuau ugugaacaag caaagcugca gcauaucaaa uauagaaacu gugauagagu      720

uccaacaaaa gaacaacaga cuacuagaga uuaccaggga auuuaguguu aaugcaggug      780

uaacuacacc uguaagcacu uacauguuaa cuaauaguga auuauuguca uuaaucaaug      840

auaugccuau aacaaaugau cagaaaaagu uaauguccaa caauguucaa auaguuagac      900

agcaaaguua cucuaucaug uccauaauaa aagaggaagu cuuagcauau guaguacaau      960

uaccacuaua ugguguuaua gauacacccu guuggaaacu acacacaucc ccucuaugua     1020

caaccaacac aaaagaaggg uccaacaucu guuuaacaag aacugacaga ggaugguacu     1080

gugacaaugc aggaucagua ucuuucuucc cacaagcuga aacauguaaa guucaaucaa     1140

aucgaguauu uugugacaca augaacaguu uaacauuacc aagugaagua aaucucugca     1200

auguugacau auucaacccc aaauaugauu guaaaauuau gacuucaaaa acagauguaa     1260

gcagcuccgu uaucacaucu cuaggagcca uugugucaug cuauggcaaa acuaaaugua     1320

cagcauccaa uaaaaaucgu ggaaucauaa agacauuuuc uaacgggugc gauuauguau     1380

caaauaaagg gguggacacu gugucuguag guaacacauu auauuaugua aauaagcaag     1440

aagguaaaag ucucuaugua aaaggugaac caauaauaaa uuucuaugac ccauuaguau     1500

uccccucuga ugaauuugau gcaucaauau cucaagucaa cgagaagauu aaccagagcc     1560

uagcauuuau ucguaaaucc gaugaauuau uacauaaugu aaaugcuggu aaauccacca     1620

caaauaucau gauaacuacu auaauuauag ugauuauagu aauauuguua ucauuaauug     1680

cuguuggacu gcucuuauac uguaaggcca gauaaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  881
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1) R3738/R3939

<400>  881
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac cugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg acgggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc uuccuccugg      480

gggugggcuc cgccaucgcg agcggcgucg ccguguccaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug agccucucca      600

acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg gugaucgagu      720

uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug aacgccgggg      780

ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc cugaucaacg      840

acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag aucguccggc      900

agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggcguac gugguccagc      960

ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc ccccugugca     1020

ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg ggcugguacu     1080

gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag gugcagagca     1140

accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacguga     1260

gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag acgaagugca     1320

ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac ccgcuggucu     1500

uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc aagagcacga     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug ucccucaucg     1680

ccguggggcu gcugcucuac ugcaaggccc ggugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  882
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  882
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc uuccuccugg      480

gggugggcuc cgcgaucgcc agcggcgucg ccguguccaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug agccucucca      600

acggcgucag cgugcugacc uccaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau cgucaacaag cagagcugcu ccaucagcaa caucgagacg gugaucgagu      720

uccagcagaa gaacaaccgc cuccuggaga ucacccggga guucagcgug aacgcggggg      780

ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc cugaucaacg      840

acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag aucguccgcc      900

agcaguccua cagcaucaug uccaucauca aggaggaggu gcuggccuac gugguccagc      960

ugccgcucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc ccccugugca     1020

ccaccaacac caaggagggg uccaacaucu gccucacgcg gaccgaccgc ggcugguacu     1080

gcgacaacgc cggcagcguc uccuucuucc cccaggccga gaccugcaag gugcagagca     1140

accggguguu cugcgacacc augaacuccc ugacgcugcc gagcgagguc aaccucugca     1200

acguggacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacguga     1260

gcuccagcgu caucaccucc cugggggcca ucgugagcug cuacggcaag acgaagugca     1320

ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cgucgacacc guguccgugg ggaacacccu guacuacguc aacaagcagg     1440

agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac ccccuggugu     1500

ucccguccga cgaguucgac gccagcaucu cccaggucaa cgagaagauc aaccagagcc     1560

uggccuucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc aagagcacga     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu cauccugcug ucccucaucg     1680

ccguggggcu gcugcucuac ugcaaggcgc gcugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  883
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  883
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc aacaacgcca      420

agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc uuccuccucg      480

gcgucggcuc cgccaucgcc uccggcgucg ccgucuccaa gguccuccac cucgagggcg      540

aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc ucccucucca      600

acggcgucuc cguccucacc uccaaggucc ucgaccucaa gaacuacauc gacaagcagc      660

uccuccccau cgucaacaag caguccugcu ccaucuccaa caucgagacc gucaucgagu      720

uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc aacgccggcg      780

ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc cucaucaacg      840

acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag aucguccgcc      900

agcaguccua cuccaucaug uccaucauca aggaggaggu ccucgccuac gucguccagc      960

ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc ccccucugca     1020

ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc ggcugguacu     1080

gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag guccagucca     1140

accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacgucu     1260

ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag accaagugca     1320

ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc gacuacgucu     1380

ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc aacaagcagg     1440

agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac ccccucgucu     1500

uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc aaccaguccc     1560

ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc aaguccacca     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc ucccucaucg     1680

ccgucggccu ccuccucuac ugcaaggccc gcugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  884
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  884
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc aauaacgcaa      420

agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc uuucucuuag      480

gggucggauc agccauagcu agcggcgugg ccguuaguaa ggugcugcac cuugaaggug      540

aggucaacaa aaucaagucc gcguugcugu cuacaaauaa agcaguggua agccuaucca      600

acgggguuuc agugcucacu ucuaaggucc uggaccuuaa aaauuauauu gauaagcaac      660

uguugccaau cgugaacaaa cagagcuguu cuauuuccaa caucgaaacc gugauagagu      720

uccagcagaa gaauaaccgg cuccuggaga uuacacgcga auuuucaguc aaugccggag      780

uuaccacgcc ggugagcacu uacauguuaa caaacaguga gcugcucucu cuuaucaaug      840

acaugcccau uaccaacgau caaaagaaac ugauguccaa uaacguacag aucgugagac      900

agcagagcua uucgaucaug ucuauuauaa aggaagaggu cuuggcuuac gugguucaac      960

uaccucugua cggcgugauc gacacuccau gcuggaaacu ccauacaucc ccacugugua     1020

ccacgaauac caaggaaggc ucaaacauuu gccuuacaag gacugaucgg gggugguauu     1080

gugacaaugc cggaaguguc agcuucuuuc cucaggcaga gaccugcaaa gugcagucca     1140

accgcguauu cugugauaca augaauaguc ugacuuugcc aagcgagguu aaccucugca     1200

auguggacau cuuuaacccc aaguacgauu guaagauaau gaccucaaaa acagacguca     1260

guuccagcgu gauuaccucu cugggugcua ucgucucaug cuauggcaag acuaaaugca     1320

cggccaguaa caagaaucga gggaucauua aaacauucag caacggaugu gauuacgugu     1380

ccaauaaggg cguugacacc gugucuguag guaacacuuu auauuacguc aauaagcaag     1440

aagggaaauc gcuguaugug aagggagagc cuaucauuaa cuuuuacgac ccccuaguuu     1500

ucccgagcga ugaauuugac gcguccauau cacaggugaa ugagaaaauc aaccagaguc     1560

ucgccuucau uagaaagucu gaugaacugc uucacaaugu caacgcaggc aaaagcacca     1620

caaauaucau gaucaccacu auuauaaucg ugauuaucgu aauuuugcug ucccucaucg     1680

cugugggccu gcuucuguac ugcaaggcca ggugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  885
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  885
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug aacaacgcca      420

agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc uuccugcugg      480

gcgugggcag cgccaucgcc agcggcgugg ccgugagcaa ggugcugcac cuggagggcg      540

aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug agccugagca      600

acggcgugag cgugcugacc agcaaggugc uggaccugaa gaacuacauc gacaagcagc      660

ugcugcccau cgugaacaag cagagcugca gcaucagcaa caucgagacc gugaucgagu      720

uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug aacgccggcg      780

ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc cugaucaacg      840

acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag aucgugagac      900

agcagagcua cagcaucaug agcaucauca aggaggaggu gcuggccuac guggugcagc      960

ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc ccccugugca     1020

ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga ggcugguacu     1080

gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag gugcagagca     1140

acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug aaccugugca     1200

acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag accgacguga     1260

gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag accaagugca     1320

ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac ccccuggugu     1500

uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc aagagcacca     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug agccugaucg     1680

ccgugggccu gcugcuguac ugcaaggcca gaugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  886
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  886
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug aauaacgcca      420

agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg uuucuccugg      480

gagugggcag cgcgauugcc uccgggguug cugugagcaa gguccuucac cuggaaggag      540

aggugaacaa aaucaagucu gcccuccugu ccacgaauaa agcuguugug agccugucua      600

acggcgucuc cgugcucaca agcaaggugc uggaccuuaa aaauuauauu gauaagcaac      660

ugcucccgau cgucaacaaa cagucuuguu ccauuagcaa caucgaaacc guuauugagu      720

uccagcagaa gaauaaccgc cugcuugaga ucacaagaga auuuuccgug aaugccggcg      780

ugaccacccc cgucucuaca uacaugcuga cgaacagcga gcuccugucc cugaucaaug      840

acaugccuau uaccaacgau caaaagaaac ucaugagcaa uaacgugcag aucguucggc      900

agcagucuua uuccauuaug agcaucauua aggaagaggu gcuggcguac gucgugcaac      960

uuccccugua cgggguuauc gacacaccuu gcuggaaacu ccauaccucu ccccugugua     1020

caaccaauac gaaggaagga agcaacaucu gccuuacacg caccgauaga ggcugguauu     1080

gugacaaugc cggguccgug ucuuucuuuc cucaggcuga gaccugcaaa guccagagca     1140

accggguguu cugugauaca augaacuccc ugacccuccc gagcgagguc aaucugugca     1200

auguggacau uuuuaacccc aaguacgauu guaagaucau gacaucuaaa acggacguuu     1260

ccagcucugu gauuaccucc cugggagcca ucgucagcug cuauggcaag acaaaaugca     1320

ccgcuuccaa caagaaucgc gggauuauca aaacauucuc uaacggaugu gauuacguga     1380

gcaauaaggg cguugacacc guguccgucg gcaacacgcu cuauuacgug aauaagcaag     1440

aagggaaauc ucuguaugug aagggagagc cuaucauuaa cuuuuacgac ccccuuguuu     1500

ucccuagcga ugaauuugac gccuccauca gccaggucaa ugagaaaauu aaccagucuc     1560

uggccuucau cagaaagucc gaugaacucc ugcacaaugu gaacgcuggc aaaagcacca     1620

caaauauuau gaucaccaca auuaucaucg ugauuaucgu cauucugcuu ucucucaucg     1680

cgguggggcu gcugcucuac ugcaaggccc ggugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  887
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  887
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaau       60

uacuaauacu caaagccaac gcaauaacaa caauacuaac agcaguaaca uucugcuucg      120

caucaggaca aaacaucaca gaagaauuuu accaaaguac augcagugca gucucuaaag      180

gauaccucag ugccuuacgc acaggauggu acacaucagu aauaacaauc gaacuuucaa      240

acauaaaaga aaacaaaugc aauggaaccg acgccaaagu aaaacuaauc aaacaagaac      300

uagacaaaua uaaaaaugca guaacagaau uacaacuccu aaugcaaucc acaccagcaa      360

caaauaacag agcaagacga gaacucccuc gauucaugaa uuacacauua aacaacgcaa      420

aaaaaacuaa cguaacuuua ucaaaaaaaa gaaaacguag auuucuagga uuccuacuag      480

gcguaggguc cgccauugca ucaggaguag caguuagcaa aguauuacau uuagaaggag      540

aaguaaauaa aaucaaaagc gcacuacucu caaccaacaa agcaguagua ucacucucaa      600

acggaguauc aguacuaaca uccaaaguac ucgaccucaa aaacuacaua gacaaacaau      660

uacuacccau aguaaacaaa caaucaugcu cuauaucaaa uaucgaaaca guaaucgaau      720

uucaacaaaa aaacaaucga cuacuugaaa uaacaagaga guucuccguc aaugccggag      780

ucaccacacc agucucaaca uacaugcuaa ccaacucuga acuccuauca cuaauaaaug      840

acaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa auaguacgac      900

aacaaaguua uuccauaaug aguauaauca aagaagaagu guuagcauac guaguccaac      960

uaccauuaua uggaguaaua gacacaccau guuggaaauu acacaccuca ccacucugca     1020

cuaccaauac aaaagaaggc ucaaauauau gccuaacucg cacagacaga ggcugguacu     1080

gcgauaacgc aggauccgua ucuuucuuuc cccaagcaga aacuugcaaa guacaaucaa     1140

acagagucuu cugcgacacc augaauaguc ucacauuacc aucugaagua aaccuaugua     1200

acguagauau auucaaucca aaauacgacu gcaaaauaau gacaucaaaa accgacgucu     1260

cuagcagugu aaucacauca cuaggagcaa uaguaagcug cuauggaaaa acaaaaugua     1320

cagcaucaaa caaaaacagg ggaauaauaa aaaccuucuc aaacggaugu gacuacguau     1380

caaauaaagg cguagacaca guaagcguag gaaacacccu auacuacguu aacaaacaag     1440

aagggaaauc auuauacgua aaaggagaac caauaauaaa cuucuacgau ccacucguau     1500

ucccauccga cgaauuugac gccagcauau cccaaguuaa cgaaaaaaua aaccaaucac     1560

uugcauuuau acgaaaaucu gaugaacuuc uccacaacgu aaaugcagga aaauccacca     1620

ccaauauaau gaucacaacu aucaucauag uaauaaucgu cauuuuacua ucauuaauag     1680

caguuggccu acuucuauac ugcaaagcaa gauaaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  888
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  888
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacuaauccu aaaagccaac gcgaucacca ccauccuaac ggcagucacc uucugcuucg      120

caucaggcca aaacaucaca gaagaguucu accaaagcac augcuccgcc guauccaaag      180

gcuaccucag cgcccuacgc acaggcuggu acacaucugu caucaccaua gaacucucca      240

acaucaaaga aaacaaaugc aacggcacug acgccaaagu aaagcugauc aaacaagaac      300

ucgacaaaua caaaaacgca gucaccgaac uccaacuacu caugcaaucc accccugcaa      360

ccaacaacag ggcccgccgc gaacuccccc gcuucaugaa cuacacuuua aacaacgcca      420

aaaagaccaa cgucacacuc agcaagaaac ggaaacgacg auuccuaggg uuucuccuag      480

gcgucggcuc ggcaaucgcc uccggcgucg ccguaagcaa aguacuacac cuagaaggcg      540

aagugaacaa aaucaaaagu gcccuucucu ccaccaacaa ggccguaguc ucucuaucca      600

acggagucuc aguccucacc ucaaaggucc ucgaccucaa aaacuacauc gacaaacaac      660

uacuccccau ugucaacaag cagucaugcu ccauaucaaa caucgaaacc gucaucgagu      720

uccaacagaa aaacaaccga cuccucgaaa uaaccagaga guucucgguc aacgccggcg      780

ucaccacccc agucagcacc uacaugcuca cuaacuccga acuccuaucc cucaucaacg      840

acaugccaau uaccaacgac caaaagaaac uaaugucgaa caacguucaa aucguccgac      900

aacaaaguua cuccaucaug agcauaauca aagaagaagu ucuagcguac gucguccaac      960

ucccacuaua cggcgucauc gacacuccgu gcuggaaacu ccacacauca ccccuaugua     1020

caaccaacac aaaagaaggc agcaacaucu gccucacccg caccgaccga gggugguauu     1080

gcgauaacgc uggcagcguc uccuucuucc cccaagccga aaccugcaaa guccaaucaa     1140

acagaguauu cugcgacacc augaacuccc uuacucuccc uagcgaaguc aaccucugca     1200

acguugacau auucaacccc aaauacgacu gcaaaaucau gaccuccaag accgacgucu     1260

ccuccuccgu caucacaucu cuaggugcca uugucuccug cuacggaaaa accaaaugca     1320

cagccuccaa caaaaaccgc ggcaucauaa aaaccuucuc caacggcugc gacuacguca     1380

guaauaaagg cgucgacacg guauccguug ggaauacgcu uuacuacgua aauaaacaag     1440

aaggcaaauc ccucuacguc aaaggugaac ccaucauaaa cuucuacgac ccgcuugugu     1500

ucccauccga cgaguucgac gccagcauca gccaggucaa cgaaaagauc aaccaauccc     1560

uagccuucau ccgcaaaagc gacgaacuac uacacaacgu caacgccgga aaauccacaa     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu aauccuacuc ucucucaucg     1680

ccgucggccu ccuacuguac uguaaagccc gauagggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  889
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (artificial)

<400>  889
gggagaaagc uuaccaugga guugcuaauc cucaaagcaa augcaauuac cacaauccuc       60

acugcaguca cauuuuguuu ugcuucuggu caaaacauca cugaagaauu uuaucaauca      120

acaugcagug caguuagcaa aggcuaucuu agugcucuga gaacugguug guauaccagu      180

guuauaacua uagaauuaag uaauaucaag gaaaauaagu guaauggaac agaugcuaag      240

guaaaauuga uaaaacaaga auuagauaaa uauaaaaaug cuguaacaga auugcaguug      300

cucaugcaaa gcacaccagc aacaaacaau cgagccagaa gagaacuacc aagguuuaug      360

aauuauacac ucaacaaugc caaaaaaacc aauguaacau uaagcaagaa aaggaaaaga      420

agauuucuug guuuuuuguu agguguugga ucugcaaucg ccaguggcgu ugcuguaucu      480

aagguccugc accuagaagg ggaagugaac aagaucaaaa gugcucuacu auccacaaac      540

aaggcuguag ucagcuuauc aaauggaguu agugucuuaa ccagcaaagu guuagaccuc      600

aaaaacuaua uagauaaaca auuguuaccu auugugaaca agcaaagcug cagcauauca      660

aauauagaaa cugugauaga guuccaacaa aagaacaaca gacuacuaga gauuaccagg      720

gaauuuagug uuaaugcagg uguaacuaca ccuguaagca cuuacauguu aacuaauagu      780

gaauuauugu cauuaaucaa ugauaugccu auaacaaaug aucagaaaaa guuaaugucc      840

aacaauguuc aaauaguuag acagcaaagu uacucuauca uguccauaau aaaagaggaa      900

gucuuagcau auguaguaca auuaccacua uaugguguua uagauacacc cuguuggaaa      960

cuacacacau ccccucuaug uacaaccaac acaaaagaag gguccaacau cuguuuaaca     1020

agaacugaca gaggauggua cugugacaau gcaggaucag uaucuuucuu cccacaagcu     1080

gaaacaugua aaguucaauc aaaucgagua uuuugugaca caaugaacag uuuaacauua     1140

ccaagugaag uaaaucucug caauguugac auauucaacc ccaaauauga uuguaaaauu     1200

augacuucaa aaacagaugu aagcagcucc guuaucacau cucuaggagc cauuguguca     1260

ugcuauggca aaacuaaaug uacagcaucc aauaaaaauc guggaaucau aaagacauuu     1320

ucuaacgggu gcgauuaugu aucaaauaaa gggguggaca cugugucugu agguaacaca     1380

uuauauuaug uaaauaagca agaagguaaa agucucuaug uaaaagguga accaauaaua     1440

aauuucuaug acccauuagu auuccccucu gaugaauuug augcaucaau aucucaaguc     1500

aacgagaaga uuaaccagag ccuagcauuu auucguaaau ccgaugaauu auuacauaau     1560

guaaaugcug guaaauccac cacaaauauc augauaacua cuauaauuau agugauuaua     1620

guaauauugu uaucauuaau ugcuguugga cugcucuuau acuguaaggc cagauaagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  890
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1) R6940

<400>  890
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

accugcagcg ccgucuccaa gggguaccuc agcgcccugc ggacgggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccaacaac cgcgcccggc gcgagcugcc ccgguucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcgcaagcgg      420

cgcuuccugg gcuuccuccu gggggugggc uccgccaucg cgagcggcgu cgccgugucc      480

aaggugcugc accucgaggg ggaggucaac aagaucaaga gcgcccugcu guccaccaac      540

aaggccgugg ugagccucuc caacggcguc agcgugcuga ccuccaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc aucgucaaca agcagagcug cuccaucagc      660

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      720

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      780

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      840

aacaacgugc agaucguccg gcagcagucc uacagcauca uguccaucau caaggaggag      900

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      960

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg     1020

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1080

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1140

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1260

ugcuacggca agacgaagug caccgccagc aacaagaacc gggggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1440

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1560

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1620

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  891
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt1)

<400>  891
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccaacaac cgggcccgcc gggagcugcc gcgcuucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcggaagcgc      420

cgguuccugg gcuuccuccu gggggugggc uccgcgaucg ccagcggcgu cgccgugucc      480

aaggugcugc accucgaggg ggaggucaac aagaucaaga gcgcccugcu guccaccaac      540

aaggccgugg ugagccucuc caacggcguc agcgugcuga ccuccaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc aucgucaaca agcagagcug cuccaucagc      660

aacaucgaga cggugaucga guuccagcag aagaacaacc gccuccugga gaucacccgg      720

gaguucagcg ugaacgcggg ggucaccacc cccgugucca cguacaugcu gaccaacagc      780

gagcuccugu cccugaucaa cgacaugccc aucaccaacg accagaagaa gcucaugagc      840

aacaacgugc agaucguccg ccagcagucc uacagcauca uguccaucau caaggaggag      900

gugcuggccu acguggucca gcugccgcuc uacggcguga ucgacacccc cugcuggaag      960

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg     1020

cggaccgacc gcggcuggua cugcgacaac gccggcagcg ucuccuucuu cccccaggcc     1080

gagaccugca aggugcagag caaccgggug uucugcgaca ccaugaacuc ccugacgcug     1140

ccgagcgagg ucaaccucug caacguggac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu gagcuccagc gucaucaccu cccugggggc caucgugagc     1260

ugcuacggca agacgaagug caccgcgagc aacaagaacc gcgggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca ccguguccgu ggggaacacc     1380

cuguacuacg ucaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1440

aacuucuacg acccccuggu guucccgucc gacgaguucg acgccagcau cucccagguc     1500

aacgagaaga ucaaccagag ccuggccuuc auccggaagu ccgacgagcu ccugcacaac     1560

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgugaucauc     1620

gucauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc gcgcugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  892
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt2)

<400>  892
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccaacaac cgcgcccgcc gcgagcuccc ccgcuucaug      360

aacuacaccc ucaacaacgc caagaagacc aacgucaccc ucuccaagaa gcgcaagcgc      420

cgcuuccucg gcuuccuccu cggcgucggc uccgccaucg ccuccggcgu cgccgucucc      480

aagguccucc accucgaggg cgaggucaac aagaucaagu ccgcccuccu cuccaccaac      540

aaggccgucg ucucccucuc caacggcguc uccguccuca ccuccaaggu ccucgaccuc      600

aagaacuaca ucgacaagca gcuccucccc aucgucaaca agcaguccug cuccaucucc      660

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      720

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      780

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      840

aacaacgucc agaucguccg ccagcagucc uacuccauca uguccaucau caaggaggag      900

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      960

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc     1020

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1080

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1140

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1260

ugcuacggca agaccaagug caccgccucc aacaagaacc gcggcaucau caagaccuuc     1320

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1380

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1440

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1500

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1560

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1620

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  893
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt3)

<400>  893
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccaacaau agggcucggc gcgaguugcc ucgauuuaug      360

aacuacacgc ucaauaacgc aaagaaaacu aaugugaccc ugucgaagaa acguaagaga      420

agguuccugg gcuuucucuu aggggucgga ucagccauag cuagcggcgu ggccguuagu      480

aaggugcugc accuugaagg ugaggucaac aaaaucaagu ccgcguugcu gucuacaaau      540

aaagcagugg uaagccuauc caacgggguu ucagugcuca cuucuaaggu ccuggaccuu      600

aaaaauuaua uugauaagca acuguugcca aucgugaaca aacagagcug uucuauuucc      660

aacaucgaaa ccgugauaga guuccagcag aagaauaacc ggcuccugga gauuacacgc      720

gaauuuucag ucaaugccgg aguuaccacg ccggugagca cuuacauguu aacaaacagu      780

gagcugcucu cucuuaucaa ugacaugccc auuaccaacg aucaaaagaa acugaugucc      840

aauaacguac agaucgugag acagcagagc uauucgauca ugucuauuau aaaggaagag      900

gucuuggcuu acgugguuca acuaccucug uacggcguga ucgacacucc augcuggaaa      960

cuccauacau ccccacugug uaccacgaau accaaggaag gcucaaacau uugccuuaca     1020

aggacugauc ggggguggua uugugacaau gccggaagug ucagcuucuu uccucaggca     1080

gagaccugca aagugcaguc caaccgcgua uucugugaua caaugaauag ucugacuuug     1140

ccaagcgagg uuaaccucug caauguggac aucuuuaacc ccaaguacga uuguaagaua     1200

augaccucaa aaacagacgu caguuccagc gugauuaccu cucugggugc uaucgucuca     1260

ugcuauggca agacuaaaug cacggccagu aacaagaauc gagggaucau uaaaacauuc     1320

agcaacggau gugauuacgu guccaauaag ggcguugaca ccgugucugu agguaacacu     1380

uuauauuacg ucaauaagca agaagggaaa ucgcuguaug ugaagggaga gccuaucauu     1440

aacuuuuacg acccccuagu uuucccgagc gaugaauuug acgcguccau aucacaggug     1500

aaugagaaaa ucaaccagag ucucgccuuc auuagaaagu cugaugaacu gcuucacaau     1560

gucaacgcag gcaaaagcac cacaaauauc augaucacca cuauuauaau cgugauuauc     1620

guaauuuugc ugucccucau cgcugugggc cugcuucugu acugcaaggc caggugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  894
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt4)

<400>  894
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccaacaac agagccagaa gagagcugcc cagauucaug      360

aacuacaccc ugaacaacgc caagaagacc aacgugaccc ugagcaagaa gagaaagaga      420

agauuccugg gcuuccugcu gggcgugggc agcgccaucg ccagcggcgu ggccgugagc      480

aaggugcugc accuggaggg cgaggugaac aagaucaaga gcgcccugcu gagcaccaac      540

aaggccgugg ugagccugag caacggcgug agcgugcuga ccagcaaggu gcuggaccug      600

aagaacuaca ucgacaagca gcugcugccc aucgugaaca agcagagcug cagcaucagc      660

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      720

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      780

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      840

aacaacgugc agaucgugag acagcagagc uacagcauca ugagcaucau caaggaggag      900

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      960

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc     1020

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1080

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1140

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1200

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1260

ugcuacggca agaccaagug caccgccagc aacaagaaca gaggcaucau caagaccuuc     1320

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1440

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1560

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1620

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  895
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt5)

<400>  895
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacaaacaau cgggcucgca gagagcuccc ucgguuuaug      360

aacuacaccc ugaauaacgc caagaaaaca aaugucaccc uuucuaagaa acgcaagaga      420

cgguuccugg gguuucuccu gggagugggc agcgcgauug ccuccggggu ugcugugagc      480

aagguccuuc accuggaagg agaggugaac aaaaucaagu cugcccuccu guccacgaau      540

aaagcuguug ugagccuguc uaacggcguc uccgugcuca caagcaaggu gcuggaccuu      600

aaaaauuaua uugauaagca acugcucccg aucgucaaca aacagucuug uuccauuagc      660

aacaucgaaa ccguuauuga guuccagcag aagaauaacc gccugcuuga gaucacaaga      720

gaauuuuccg ugaaugccgg cgugaccacc cccgucucua cauacaugcu gacgaacagc      780

gagcuccugu cccugaucaa ugacaugccu auuaccaacg aucaaaagaa acucaugagc      840

aauaacgugc agaucguucg gcagcagucu uauuccauua ugagcaucau uaaggaagag      900

gugcuggcgu acgucgugca acuuccccug uacgggguua ucgacacacc uugcuggaaa      960

cuccauaccu cuccccugug uacaaccaau acgaaggaag gaagcaacau cugccuuaca     1020

cgcaccgaua gaggcuggua uugugacaau gccggguccg ugucuuucuu uccucaggcu     1080

gagaccugca aaguccagag caaccgggug uucugugaua caaugaacuc ccugacccuc     1140

ccgagcgagg ucaaucugug caauguggac auuuuuaacc ccaaguacga uuguaagauc     1200

augacaucua aaacggacgu uuccagcucu gugauuaccu cccugggagc caucgucagc     1260

ugcuauggca agacaaaaug caccgcuucc aacaagaauc gcgggauuau caaaacauuc     1320

ucuaacggau gugauuacgu gagcaauaag ggcguugaca ccguguccgu cggcaacacg     1380

cucuauuacg ugaauaagca agaagggaaa ucucuguaug ugaagggaga gccuaucauu     1440

aacuuuuacg acccccuugu uuucccuagc gaugaauuug acgccuccau cagccagguc     1500

aaugagaaaa uuaaccaguc ucuggccuuc aucagaaagu ccgaugaacu ccugcacaau     1560

gugaacgcug gcaaaagcac cacaaauauu augaucacca caauuaucau cgugauuauc     1620

gucauucugc uuucucucau cgcggugggg cugcugcucu acugcaaggc ccggugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  896
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt6)

<400>  896
gggagaaagc uuaccaugga auuacuaaua cucaaagcca acgcaauaac aacaauacua       60

acagcaguaa cauucugcuu cgcaucagga caaaacauca cagaagaauu uuaccaaagu      120

acaugcagug cagucucuaa aggauaccuc agugccuuac gcacaggaug guacacauca      180

guaauaacaa ucgaacuuuc aaacauaaaa gaaaacaaau gcaauggaac cgacgccaaa      240

guaaaacuaa ucaaacaaga acuagacaaa uauaaaaaug caguaacaga auuacaacuc      300

cuaaugcaau ccacaccagc aacaaauaac agagcaagac gagaacuccc ucgauucaug      360

aauuacacau uaaacaacgc aaaaaaaacu aacguaacuu uaucaaaaaa aagaaaacgu      420

agauuucuag gauuccuacu aggcguaggg uccgccauug caucaggagu agcaguuagc      480

aaaguauuac auuuagaagg agaaguaaau aaaaucaaaa gcgcacuacu cucaaccaac      540

aaagcaguag uaucacucuc aaacggagua ucaguacuaa cauccaaagu acucgaccuc      600

aaaaacuaca uagacaaaca auuacuaccc auaguaaaca aacaaucaug cucuauauca      660

aauaucgaaa caguaaucga auuucaacaa aaaaacaauc gacuacuuga aauaacaaga      720

gaguucuccg ucaaugccgg agucaccaca ccagucucaa cauacaugcu aaccaacucu      780

gaacuccuau cacuaauaaa ugacaugcca auaacaaacg accaaaaaaa acuaauguca      840

aauaacguac aaauaguacg acaacaaagu uauuccauaa ugaguauaau caaagaagaa      900

guguuagcau acguagucca acuaccauua uauggaguaa uagacacacc auguuggaaa      960

uuacacaccu caccacucug cacuaccaau acaaaagaag gcucaaauau augccuaacu     1020

cgcacagaca gaggcuggua cugcgauaac gcaggauccg uaucuuucuu uccccaagca     1080

gaaacuugca aaguacaauc aaacagaguc uucugcgaca ccaugaauag ucucacauua     1140

ccaucugaag uaaaccuaug uaacguagau auauucaauc caaaauacga cugcaaaaua     1200

augacaucaa aaaccgacgu cucuagcagu guaaucacau cacuaggagc aauaguaagc     1260

ugcuauggaa aaacaaaaug uacagcauca aacaaaaaca ggggaauaau aaaaaccuuc     1320

ucaaacggau gugacuacgu aucaaauaaa ggcguagaca caguaagcgu aggaaacacc     1380

cuauacuacg uuaacaaaca agaagggaaa ucauuauacg uaaaaggaga accaauaaua     1440

aacuucuacg auccacucgu auucccaucc gacgaauuug acgccagcau aucccaaguu     1500

aacgaaaaaa uaaaccaauc acuugcauuu auacgaaaau cugaugaacu ucuccacaac     1560

guaaaugcag gaaaauccac caccaauaua augaucacaa cuaucaucau aguaauaauc     1620

gucauuuuac uaucauuaau agcaguuggc cuacuucuau acugcaaagc aagauaagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  897
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del (opt11)

<400>  897
gggagaaagc uuaccaugga acuacuaauc cuaaaagcca acgcgaucac caccauccua       60

acggcaguca ccuucugcuu cgcaucaggc caaaacauca cagaagaguu cuaccaaagc      120

acaugcuccg ccguauccaa aggcuaccuc agcgcccuac gcacaggcug guacacaucu      180

gucaucacca uagaacucuc caacaucaaa gaaaacaaau gcaacggcac ugacgccaaa      240

guaaagcuga ucaaacaaga acucgacaaa uacaaaaacg cagucaccga acuccaacua      300

cucaugcaau ccaccccugc aaccaacaac agggcccgcc gcgaacuccc ccgcuucaug      360

aacuacacuu uaaacaacgc caaaaagacc aacgucacac ucagcaagaa acggaaacga      420

cgauuccuag gguuucuccu aggcgucggc ucggcaaucg ccuccggcgu cgccguaagc      480

aaaguacuac accuagaagg cgaagugaac aaaaucaaaa gugcccuucu cuccaccaac      540

aaggccguag ucucucuauc caacggaguc ucaguccuca ccucaaaggu ccucgaccuc      600

aaaaacuaca ucgacaaaca acuacucccc auugucaaca agcagucaug cuccauauca      660

aacaucgaaa ccgucaucga guuccaacag aaaaacaacc gacuccucga aauaaccaga      720

gaguucucgg ucaacgccgg cgucaccacc ccagucagca ccuacaugcu cacuaacucc      780

gaacuccuau cccucaucaa cgacaugcca auuaccaacg accaaaagaa acuaaugucg      840

aacaacguuc aaaucguccg acaacaaagu uacuccauca ugagcauaau caaagaagaa      900

guucuagcgu acgucgucca acucccacua uacggcguca ucgacacucc gugcuggaaa      960

cuccacacau caccccuaug uacaaccaac acaaaagaag gcagcaacau cugccucacc     1020

cgcaccgacc gaggguggua uugcgauaac gcuggcagcg ucuccuucuu cccccaagcc     1080

gaaaccugca aaguccaauc aaacagagua uucugcgaca ccaugaacuc ccuuacucuc     1140

ccuagcgaag ucaaccucug caacguugac auauucaacc ccaaauacga cugcaaaauc     1200

augaccucca agaccgacgu cuccuccucc gucaucacau cucuaggugc cauugucucc     1260

ugcuacggaa aaaccaaaug cacagccucc aacaaaaacc gcggcaucau aaaaaccuuc     1320

uccaacggcu gcgacuacgu caguaauaaa ggcgucgaca cgguauccgu ugggaauacg     1380

cuuuacuacg uaaauaaaca agaaggcaaa ucccucuacg ucaaagguga acccaucaua     1440

aacuucuacg acccgcuugu guucccaucc gacgaguucg acgccagcau cagccagguc     1500

aacgaaaaga ucaaccaauc ccuagccuuc auccgcaaaa gcgacgaacu acuacacaac     1560

gucaacgccg gaaaauccac aaccaacauc augaucacca ccaucaucau cgucaucauc     1620

guaauccuac ucucucucau cgccgucggc cuccuacugu acuguaaagc ccgauaggga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  898
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F0_DSCav1

<400>  898

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Cys Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Phe Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Cys Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  899
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F0_DSCav1

<400>  899
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaacca acaaccgcgc ccggcgcgag cugccccggu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgca agcggcgcuu ccugggcuuc      420

cuccuggggg ugggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acuga                     1725


<210>  900
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F0_DSCav1

<400>  900
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccacca acaaccgggc ccgccgggag cugccgcgcu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgga agcgccgguu ccugggcuuc      420

cuccuggggg ugggcuccgc gaucgccagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caaguccgcc cugcugagca ccaacaaggc cguggugucc      540

cucagcaacg gcgucuccgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu caacaagcag agcugcucca ucagcaacau cgagacgguc      660

aucgaguucc agcagaagaa caaccgccug cuggagauca cccgggaguu cuccgugaac      720

gcggggguga ccacccccgu cagcacguac augcucacca acagcgagcu gcugucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugcgccagc aguccuacag caucaugugc aucaucaagg aggagguccu ggccuacgug      900

gugcagcucc cgcuguacgg cgucaucgac acccccugcu ggaagcugca cacgagcccc      960

cucugcacca ccaacaccaa ggaggggagc aacaucugcc ugacgcggac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc ggguguucug cgacaccaug aacagccuga cgcucccguc cgaggugaac     1140

cugugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgugau caccagccug ggggccaucg ucuccugcua cggcaagacg     1260

aagugcaccg cgagcaacaa gaaccgcggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccguc agcgugggga acacccucua cuacgugaac     1380

aagcaggagg gcaagucccu guacgucaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggugaacga gaagaucaac     1500

cagucccucg ccuucauccg gaaguccgac gagcugcugc acaacgucaa cgccggcaag     1560

uccacgacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcucagc     1620

cugaucgccg ucgggcugcu ccuguacugc aaggcgcgcu ccacgcccgu gacccugagc     1680

aaggaccagc ucuccggcau caacaacauc gccuucagca acuga                     1725


<210>  901
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F0_DSCav1

<400>  901
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccacca acaaccgcgc ccgccgcgag cucccccgcu ucaugaacua cacccucaac      360

aacgccaaga agaccaacgu cacccucucc aagaagcgca agcgccgcuu ccucggcuuc      420

cuccucggcg ucggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acuga                     1725


<210>  902
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F0_DSCav1

<400>  902
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccacca acaauagggc ucggcgcgag uugccucgau uuaugaacua cacgcucaau      360

aacgcaaaga aaacuaaugu gacccugucg aagaaacgua agagaagguu ccugggcuuu      420

cucuuagggg ucggaucagc cauagcuagc ggcguggccg uuuguaaggu gcugcaccuu      480

gaaggugagg ucaacaaaau caagagugcg uugcugucca caaauaaagc agugguaucu      540

cuaagcaacg ggguuuccgu gcucacuuuc aagguccugg accuuaaaaa uuauauugau      600

aagcaacugu ugccaauccu caacaaacag ucaugcagua uuagcaacau cgaaaccgug      660

auagaguuuc agcagaagaa uaaccggcug uuagagauua cacgcgaguu cucugugaau      720

gccggaguca ccacgccggu uuccacuuac augcugacaa acucagaacu ccuuagccug      780

aucaaugaca ugcccauuac caacgaucaa aagaaauuga ugaguaauaa cgugcagauc      840

guaagacagc agucuuauuc caucaugugu auuauaaagg aagaggugcu agcuuacguc      900

gugcaacugc cucucuacgg cguuaucgac acuccaugcu ggaaacugca uacaagcccc      960

cuuuguacca cgaauaccaa ggaaggcucg aacauuugcc ugacaaggac ugaucggggg     1020

ugguauugug acaaugccgg aucugugucc uuuuucccuc aggcagagac cugcaaaguc     1080

cagucaaacc gcguguuuug ugauacaaug aauaguuuga cucucccaag cgagguaaac     1140

cugugcaaug uugacaucuu caaccccaag uacgauugca agauaaugac cuccaaaaca     1200

gacgugucua gcucagucau uaccaguuua ggugcuaucg uguccuguua uggcaagacu     1260

aaaugcacgg ccagcaacaa gaaucgaggg aucauuaaaa cauuuucuaa cggaugugau     1320

uacgucucaa auaagggcgu ggacaccguu agugugggua acacucugua uuacguaaau     1380

aagcaagaag ggaaaagccu auaugucaag ggagagccua ucauuaacuu cuacgaccca     1440

cucguguucc cguccgauga auuugacgcg ucuauaucgc agguuaauga gaaaaucaac     1500

cagagccugg ccuucauuag aaaguccgau gaacuuuugc acaaugugaa cgcaggcaaa     1560

ucaaccacaa auaucaugau caccacuauu auaaucguca uuaucgugau ucugcucagu     1620

cugaucgcug uaggccuucu guuguacugc aaggccaggu cuacacccgu gacgcucagc     1680

aaggaccagc uguccgggau aaacaauauc gcuuuuucaa acuga                     1725


<210>  903
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F0_DSCav1

<400>  903
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccacca acaacagagc cagaagagag cugcccagau ucaugaacua cacccugaac      360

aacgccaaga agaccaacgu gacccugagc aagaagagaa agagaagauu ccugggcuuc      420

cugcugggcg ugggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acuga                     1725


<210>  904
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F0_DSCav1

<400>  904
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacaa acaaucgggc ucgcagagag cucccucggu uuaugaacua cacccugaau      360

aacgccaaga aaacaaaugu cacccuuucu aagaaacgca agagacgguu ccugggguuu      420

cuccugggag ugggcagcgc gauugccucc gggguugcug uguguaaggu ccuucaccug      480

gaaggagagg ugaacaaaau caagagcgcc cuccugucua cgaauaaagc uguugugucc      540

cugagcaacg gcgucucugu gcucacauuc aaggugcugg accuuaaaaa uuauauugau      600

aagcaacugc ucccgauccu gaacaaacag uccugcagca uuucuaacau cgaaaccguc      660

auugaguuuc agcagaagaa uaaccgccuu cuggagauca caagagaauu uuccguuaau      720

gccggcguga ccacccccgu gagcacauac augcucacga acuccgagcu gcugucucuc      780

aucaaugaca ugccuauuac caacgaucaa aagaaacuga ugagcaauaa cguccagauc      840

gugcggcagc aguccuauag cauuaugugu aucauuaagg aagagguucu ugcguacgug      900

guccaacugc cccucuacgg ggugaucgac acaccuugcu ggaaacugca uaccucuccc      960

cuuuguacaa ccaauacgaa ggaaggaucc aacaucugcc ugacacgcac cgauagaggc     1020

ugguauugug acaaugccgg gagcguuucu uucuucccuc aggcugagac cugcaaagug     1080

cagagcaacc gggucuuuug ugauacaaug aacucccuca cccugccguc ugaggugaau     1140

cugugcaaug ucgacauuuu caaccccaag uacgauugca agaucaugac aagcaaaacg     1200

gacgugucca gcucuguuau uaccucccuc ggagccaucg ugagcuguua uggcaagaca     1260

aaaugcaccg cuucuaacaa gaaucgcggg auuaucaaaa cauuuuccaa cggaugugau     1320

uacgucagca auaagggcgu ggacaccguu uccgugggca acacgcugua uuacgucaau     1380

aagcaagaag ggaaaucucu uuaugugaag ggagagccua ucauuaacuu cuacgacccc     1440

cugguguucc cuagcgauga auuugacgcc uccaucucuc agguuaauga gaaaauuaac     1500

cagagccucg ccuucaucag aaaguccgau gaacugcugc acaaugucaa cgcuggcaaa     1560

agcaccacaa auauuaugau caccacaauu aucaucguga uuaucgugau ucuucucucu     1620

cugaucgcgg ucgggcugcu ccuguacugc aaggcccggu ccacccccgu gacgcuuagc     1680

aaggaccagc ugucuggaau uaacaauauc gcuuuuucca acuga                     1725


<210>  905
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F0_DSCav1

<400>  905
auggaauuau uaauccucaa agcgaacgcu auuacuacca uucuaacagc agucacauuc       60

ugcuucgccu caggccaaaa cauuacagaa gaauuuuacc aaucaacaug cucugccgua      120

ucaaaaggcu accuauccgc ccuacgaaca ggcugguaca caagcguaau aacaaucgaa      180

cuaucaaaca uaaaagaaaa caaaugcaac gguacagacg ccaaaguuaa acuaauaaaa      240

caagaacucg auaaauacaa aaacgcagua acagaauuac aacuacuaau gcaaucaaca      300

ccugcaacaa acaauagagc caggagagaa uuaccucgau ucaugaauua cacacucaau      360

aacgcaaaaa aaaccaacgu uacacuauca aaaaaaagaa aacgacgauu cuuaggauuc      420

cuacucggag ucggaucagc aauagcaucu ggcguugcag uaugcaaagu auuacacuua      480

gaaggugaag ucaauaaaau aaaaagcgcg cuacuaagua caaacaaagc agucgucucc      540

cuaucaaacg gagucucagu ccuaacauuc aaaguacucg accuaaaaaa uuacauagau      600

aaacaacuac uuccaauauu aaacaaacaa uccuguagca ucagcaauau agaaacagua      660

auagaauuuc aacaaaaaaa caaccgauua uuagaaauca cucgagaauu uuccguaaac      720

gccgggguaa caacuccagu cucaaccuac augcuaacca auucagaacu auugagcuua      780

auaaacgaca ugccaauaac caacgaccaa aaaaaacuaa ugucuaacaa uguucaaauc      840

gucagacaac aaaguuacag uauaaugugu auaaucaaag aagaaguccu agcauacgua      900

guccaacucc cacuauaugg aguuaucgac acaccauguu ggaaauuaca caccucacca      960

uuaugcacaa ccaauacaaa agaaggauca aacauaugcc uuacacggac agaccgcgga     1020

ugguauugug acaacgcugg cucagucucc uuuuucccac aagcagaaac augcaaagua     1080

caaucaaaca gagucuuuug cgauaccaug aacucacuua cauuaccaag cgaaguaaau     1140

cuuuguaacg ucgacaucuu caauccuaaa uaugacugca aaaucaugac cucaaaaaca     1200

gacguuagcu cuucaguaau cacuagcuua ggagcaaucg uaucaugcua cggcaaaaca     1260

aaauguacag caucaaauaa aaacagagga aucauaaaaa cauuuucaaa cggaugcgau     1320

uauguaagca acaaaggagu agauacugua agcguaggaa acacauugua cuauguaaac     1380

aaacaagaag gaaaaucacu cuauguaaaa ggagaaccua uaaucaauuu cuacgaucca     1440

uuaguguucc caucagauga auuugacgcc ucaauaucac aaguuaauga aaaaauaaau     1500

caaucgcuag cauucauacg uaaaucagau gaauuacuac auaacguaaa cgcaggcaaa     1560

uccacaacaa auaucaugau cacaacaauu auaauaguaa uaauaguaau acuacuauca     1620

cuaauagccg uaggacuccu acuauacugc aaagcaagau cuacuccagu aacccucuca     1680

aaagaucaac uaagcggaau uaauaacauc gcauucagca acuaa                     1725


<210>  906
<211>  1725
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F0_DSCav1

<400>  906
auggaacuac uuauccucaa agccaacgcc aucaccacca uccucacagc aguaaccuuu       60

ugcuucgccu caggccaaaa uaucacagaa gaauuuuacc agaguaccug cuccgccgua      120

uccaaaggau accucagcgc gcuccgcacc ggcugguaca cuucaguaau cacaaucgaa      180

cuauccaaca ucaaagaaaa caaaugcaac ggcaccgacg cgaaagucaa acucaucaaa      240

caagaacuag acaaauacaa aaaugccgua acagaacuac aacuguuaau gcagagcaca      300

cccgccacca acaaccgcgc ccgccgggaa cucccccgau ucaugaacua cacacucaac      360

aacgccaaaa agacgaacgu cacccucagc aagaaacgaa aacgcagauu ccucgguuuc      420

cuacuaggcg uaggcucagc aauagccucc ggaguagccg ucugcaaagu ccugcacuua      480

gaaggcgaag ucaacaaaau caaauccgcc cuacucucca cgaacaaagc cgucgucucc      540

cuguccaacg gugucuccgu uuuaaccuuc aaaguucugg accucaaaaa cuacauagac      600

aaacagcuuc uccccauccu caacaaacaa uccuguagca ucuccaacau cgaaaccguc      660

auagaauuuc aacagaaaaa caacagacug cucgaaauca cccgcgaguu cuccgucaac      720

gccggcguca cgacucccgu cuccaccuau augcucacga acucggaacu ccuuucccua      780

aucaacgaca ugccgaucac caacgaccaa aagaaacuca ugucaaacaa cguacaaauu      840

guccgccaac aaucauacuc caucaugugc auaauuaaag aagaaguccu cgcauacgua      900

guccaacucc cccucuacgg cgucaucgac acccccugcu ggaaacucca caccucccca      960

cucugcacaa ccaacaccaa agaaggcuca aacauaugcc uaacgcgcac cgaucgcggu     1020

ugguacugcg acaacgccgg uuccgucagc uucuuccccc aagcagagac augcaaaguc     1080

caaucaaacc gcgucuucug cgacaccaug aacucacuaa cccuuccaag cgaagucaac     1140

cucugcaacg uugacaucuu caaccccaaa uacgacugua aaaucaugac cuccaagacc     1200

gacguauccu cuuccgucau cacaucccua ggcgcuaucg uauccugcua ugguaaaacc     1260

aaaugcaccg ccuccaacaa aaaccgcggc aucaucaaga cauuuuccaa cggcugcgac     1320

uacgugagca acaaaggcgu cgacaccguc uccguaggca acacccucua cuauguaaac     1380

aaacaagagg gcaaaucacu cuacgucaaa ggggaaccca ucaucaacuu cuacgacccg     1440

cucguauucc ccagcgauga guucgacgcc uccaucuccc aggucaacga aaagauaaac     1500

caaucacucg cauucauucg uaaauccgac gaacuccuac acaacgugaa ugcaggcaaa     1560

ucgaccacua acaucaugau caccaccauc aucaucguca ucauagucau ccuccugucc     1620

cuuaucgccg ucggucuuuu auuauacugc aaagcccgca gcacccccgu cacccucucu     1680

aaggaccaac ucagcggcau caauaacauc gcauucucua acuaa                     1725


<210>  907
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  907
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  908
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  908
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcucca     1740

cgcccgugac ccugagcaag gaccagcucu ccggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  909
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  909
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  910
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  910
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggucua     1740

cacccgugac gcucagcaag gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  911
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  911
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  912
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  912
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggucca     1740

cccccgugac gcuuagcaag gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu     1800

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  913
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  913
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc      120

uaacagcagu cacauucugc uucgccucag gccaaaacau uacagaagaa uuuuaccaau      180

caacaugcuc ugccguauca aaaggcuacc uauccgcccu acgaacaggc ugguacacaa      240

gcguaauaac aaucgaacua ucaaacauaa aagaaaacaa augcaacggu acagacgcca      300

aaguuaaacu aauaaaacaa gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aucaacaccu gcaacaaaca auagagccag gagagaauua ccucgauuca      420

ugaauuacac acucaauaac gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac      480

gacgauucuu aggauuccua cucggagucg gaucagcaau agcaucuggc guugcaguau      540

gcaaaguauu acacuuagaa ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa      600

acaaagcagu cgucucccua ucaaacggag ucucaguccu aacauucaaa guacucgacc      660

uaaaaaauua cauagauaaa caacuacuuc caauauuaaa caaacaaucc uguagcauca      720

gcaauauaga aacaguaaua gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc      780

gagaauuuuc cguaaacgcc gggguaacaa cuccagucuc aaccuacaug cuaaccaauu      840

cagaacuauu gagcuuaaua aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu      900

cuaacaaugu ucaaaucguc agacaacaaa guuacaguau aauguguaua aucaaagaag      960

aaguccuagc auacguaguc caacucccac uauauggagu uaucgacaca ccauguugga     1020

aauuacacac cucaccauua ugcacaacca auacaaaaga aggaucaaac auaugccuua     1080

cacggacaga ccgcggaugg uauugugaca acgcuggcuc agucuccuuu uucccacaag     1140

cagaaacaug caaaguacaa ucaaacagag ucuuuugcga uaccaugaac ucacuuacau     1200

uaccaagcga aguaaaucuu uguaacgucg acaucuucaa uccuaaauau gacugcaaaa     1260

ucaugaccuc aaaaacagac guuagcucuu caguaaucac uagcuuagga gcaaucguau     1320

caugcuacgg caaaacaaaa uguacagcau caaauaaaaa cagaggaauc auaaaaacau     1380

uuucaaacgg augcgauuau guaagcaaca aaggaguaga uacuguaagc guaggaaaca     1440

cauuguacua uguaaacaaa caagaaggaa aaucacucua uguaaaagga gaaccuauaa     1500

ucaauuucua cgauccauua guguucccau cagaugaauu ugacgccuca auaucacaag     1560

uuaaugaaaa aauaaaucaa ucgcuagcau ucauacguaa aucagaugaa uuacuacaua     1620

acguaaacgc aggcaaaucc acaacaaaua ucaugaucac aacaauuaua auaguaauaa     1680

uaguaauacu acuaucacua auagccguag gacuccuacu auacugcaaa gcaagaucua     1740

cuccaguaac ccucucaaaa gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu     1800

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  914
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  914
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuua uccucaaagc caacgccauc accaccaucc      120

ucacagcagu aaccuuuugc uucgccucag gccaaaauau cacagaagaa uuuuaccaga      180

guaccugcuc cgccguaucc aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu      240

caguaaucac aaucgaacua uccaacauca aagaaaacaa augcaacggc accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa ugccguaaca gaacuacaac      360

uguuaaugca gagcacaccc gccaccaaca accgcgcccg ccgggaacuc ccccgauuca      420

ugaacuacac acucaacaac gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac      480

gcagauuccu cgguuuccua cuaggcguag gcucagcaau agccuccgga guagccgucu      540

gcaaaguccu gcacuuagaa ggcgaaguca acaaaaucaa auccgcccua cucuccacga      600

acaaagccgu cgucucccug uccaacggug ucuccguuuu aaccuucaaa guucuggacc      660

ucaaaaacua cauagacaaa cagcuucucc ccauccucaa caaacaaucc uguagcaucu      720

ccaacaucga aaccgucaua gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacga cucccgucuc caccuauaug cucacgaacu      840

cggaacuccu uucccuaauc aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu      900

caaacaacgu acaaauuguc cgccaacaau cauacuccau caugugcaua auuaaagaag      960

aaguccucgc auacguaguc caacuccccc ucuacggcgu caucgacacc cccugcugga     1020

aacuccacac cuccccacuc ugcacaacca acaccaaaga aggcucaaac auaugccuaa     1080

cgcgcaccga ucgcgguugg uacugcgaca acgccgguuc cgucagcuuc uucccccaag     1140

cagagacaug caaaguccaa ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc     1200

uuccaagcga agucaaccuc ugcaacguug acaucuucaa ccccaaauac gacuguaaaa     1260

ucaugaccuc caagaccgac guauccucuu ccgucaucac aucccuaggc gcuaucguau     1320

ccugcuaugg uaaaaccaaa ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau     1380

uuuccaacgg cugcgacuac gugagcaaca aaggcgucga caccgucucc guaggcaaca     1440

cccucuacua uguaaacaaa caagagggca aaucacucua cgucaaaggg gaacccauca     1500

ucaacuucua cgacccgcuc guauucccca gcgaugaguu cgacgccucc aucucccagg     1560

ucaacgaaaa gauaaaccaa ucacucgcau ucauucguaa auccgacgaa cuccuacaca     1620

acgugaaugc aggcaaaucg accacuaaca ucaugaucac caccaucauc aucgucauca     1680

uagucauccu ccugucccuu aucgccgucg gucuuuuauu auacugcaaa gcccgcagca     1740

cccccgucac ccucucuaag gaccaacuca gcggcaucaa uaacaucgca uucucuaacu     1800

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1860

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  915
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  915
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  916
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  916
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcuccac gcccgugacc cugagcaagg accagcucuc cggcaucaac     1800

aacaucgccu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  917
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  917
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  918
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  918
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggucuac acccgugacg cucagcaagg accagcuguc cgggauaaac     1800

aauaucgcuu uuucaaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  919
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  919
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  920
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  920
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccgguccac ccccgugacg cuuagcaagg accagcuguc uggaauuaac     1800

aauaucgcuu uuuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  921
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  921
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuauuaau ccucaaagcg      120

aacgcuauua cuaccauucu aacagcaguc acauucugcu ucgccucagg ccaaaacauu      180

acagaagaau uuuaccaauc aacaugcucu gccguaucaa aaggcuaccu auccgcccua      240

cgaacaggcu gguacacaag cguaauaaca aucgaacuau caaacauaaa agaaaacaaa      300

ugcaacggua cagacgccaa aguuaaacua auaaaacaag aacucgauaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa ucaacaccug caacaaacaa uagagccagg      420

agagaauuac cucgauucau gaauuacaca cucaauaacg caaaaaaaac caacguuaca      480

cuaucaaaaa aaagaaaacg acgauucuua ggauuccuac ucggagucgg aucagcaaua      540

gcaucuggcg uugcaguaug caaaguauua cacuuagaag gugaagucaa uaaaauaaaa      600

agcgcgcuac uaaguacaaa caaagcaguc gucucccuau caaacggagu cucaguccua      660

acauucaaag uacucgaccu aaaaaauuac auagauaaac aacuacuucc aauauuaaac      720

aaacaauccu guagcaucag caauauagaa acaguaauag aauuucaaca aaaaaacaac      780

cgauuauuag aaaucacucg agaauuuucc guaaacgccg ggguaacaac uccagucuca      840

accuacaugc uaaccaauuc agaacuauug agcuuaauaa acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaauguc uaacaauguu caaaucguca gacaacaaag uuacaguaua      960

auguguauaa ucaaagaaga aguccuagca uacguagucc aacucccacu auauggaguu     1020

aucgacacac cauguuggaa auuacacacc ucaccauuau gcacaaccaa uacaaaagaa     1080

ggaucaaaca uaugccuuac acggacagac cgcggauggu auugugacaa cgcuggcuca     1140

gucuccuuuu ucccacaagc agaaacaugc aaaguacaau caaacagagu cuuuugcgau     1200

accaugaacu cacuuacauu accaagcgaa guaaaucuuu guaacgucga caucuucaau     1260

ccuaaauaug acugcaaaau caugaccuca aaaacagacg uuagcucuuc aguaaucacu     1320

agcuuaggag caaucguauc augcuacggc aaaacaaaau guacagcauc aaauaaaaac     1380

agaggaauca uaaaaacauu uucaaacgga ugcgauuaug uaagcaacaa aggaguagau     1440

acuguaagcg uaggaaacac auuguacuau guaaacaaac aagaaggaaa aucacucuau     1500

guaaaaggag aaccuauaau caauuucuac gauccauuag uguucccauc agaugaauuu     1560

gacgccucaa uaucacaagu uaaugaaaaa auaaaucaau cgcuagcauu cauacguaaa     1620

ucagaugaau uacuacauaa cguaaacgca ggcaaaucca caacaaauau caugaucaca     1680

acaauuauaa uaguaauaau aguaauacua cuaucacuaa uagccguagg acuccuacua     1740

uacugcaaag caagaucuac uccaguaacc cucucaaaag aucaacuaag cggaauuaau     1800

aacaucgcau ucagcaacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  922
<211>  2020
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  922
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuuau ccucaaagcc      120

aacgccauca ccaccauccu cacagcagua accuuuugcu ucgccucagg ccaaaauauc      180

acagaagaau uuuaccagag uaccugcucc gccguaucca aaggauaccu cagcgcgcuc      240

cgcaccggcu gguacacuuc aguaaucaca aucgaacuau ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa auacaaaaau      360

gccguaacag aacuacaacu guuaaugcag agcacacccg ccaccaacaa ccgcgcccgc      420

cgggaacucc cccgauucau gaacuacaca cucaacaacg ccaaaaagac gaacgucacc      480

cucagcaaga aacgaaaacg cagauuccuc gguuuccuac uaggcguagg cucagcaaua      540

gccuccggag uagccgucug caaaguccug cacuuagaag gcgaagucaa caaaaucaaa      600

uccgcccuac ucuccacgaa caaagccguc gucucccugu ccaacggugu cuccguuuua      660

accuucaaag uucuggaccu caaaaacuac auagacaaac agcuucuccc cauccucaac      720

aaacaauccu guagcaucuc caacaucgaa accgucauag aauuucaaca gaaaaacaac      780

agacugcucg aaaucacccg cgaguucucc gucaacgccg gcgucacgac ucccgucucc      840

accuauaugc ucacgaacuc ggaacuccuu ucccuaauca acgacaugcc gaucaccaac      900

gaccaaaaga aacucauguc aaacaacgua caaauugucc gccaacaauc auacuccauc      960

augugcauaa uuaaagaaga aguccucgca uacguagucc aacucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa acuccacacc uccccacucu gcacaaccaa caccaaagaa     1080

ggcucaaaca uaugccuaac gcgcaccgau cgcgguuggu acugcgacaa cgccgguucc     1140

gucagcuucu ucccccaagc agagacaugc aaaguccaau caaaccgcgu cuucugcgac     1200

accaugaacu cacuaacccu uccaagcgaa gucaaccucu gcaacguuga caucuucaac     1260

cccaaauacg acuguaaaau caugaccucc aagaccgacg uauccucuuc cgucaucaca     1320

ucccuaggcg cuaucguauc cugcuauggu aaaaccaaau gcaccgccuc caacaaaaac     1380

cgcggcauca ucaagacauu uuccaacggc ugcgacuacg ugagcaacaa aggcgucgac     1440

accgucuccg uaggcaacac ccucuacuau guaaacaaac aagagggcaa aucacucuac     1500

gucaaagggg aacccaucau caacuucuac gacccgcucg uauuccccag cgaugaguuc     1560

gacgccucca ucucccaggu caacgaaaag auaaaccaau cacucgcauu cauucguaaa     1620

uccgacgaac uccuacacaa cgugaaugca ggcaaaucga ccacuaacau caugaucacc     1680

accaucauca ucgucaucau agucauccuc cugucccuua ucgccgucgg ucuuuuauua     1740

uacugcaaag cccgcagcac ccccgucacc cucucuaagg accaacucag cggcaucaau     1800

aacaucgcau ucucuaacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1860

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1980

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2020


<210>  923
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  923
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  924
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  924
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcuccacgc ccgugacccu gagcaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc agcaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  925
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  925
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  926
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  926
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggucuacac ccgugacgcu cagcaaggac     1860

cagcuguccg ggauaaacaa uaucgcuuuu ucaaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  927
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  927
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  928
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  928
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cgguccaccc ccgugacgcu uagcaaggac     1860

cagcugucug gaauuaacaa uaucgcuuuu uccaacugag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  929
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  929
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuauuaaucc ucaaagcgaa cgcuauuacu accauucuaa cagcagucac auucugcuuc      240

gccucaggcc aaaacauuac agaagaauuu uaccaaucaa caugcucugc cguaucaaaa      300

ggcuaccuau ccgcccuacg aacaggcugg uacacaagcg uaauaacaau cgaacuauca      360

aacauaaaag aaaacaaaug caacgguaca gacgccaaag uuaaacuaau aaaacaagaa      420

cucgauaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaauc aacaccugca      480

acaaacaaua gagccaggag agaauuaccu cgauucauga auuacacacu caauaacgca      540

aaaaaaacca acguuacacu aucaaaaaaa agaaaacgac gauucuuagg auuccuacuc      600

ggagucggau cagcaauagc aucuggcguu gcaguaugca aaguauuaca cuuagaaggu      660

gaagucaaua aaauaaaaag cgcgcuacua aguacaaaca aagcagucgu cucccuauca      720

aacggagucu caguccuaac auucaaagua cucgaccuaa aaaauuacau agauaaacaa      780

cuacuuccaa uauuaaacaa acaauccugu agcaucagca auauagaaac aguaauagaa      840

uuucaacaaa aaaacaaccg auuauuagaa aucacucgag aauuuuccgu aaacgccggg      900

guaacaacuc cagucucaac cuacaugcua accaauucag aacuauugag cuuaauaaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugucua acaauguuca aaucgucaga     1020

caacaaaguu acaguauaau guguauaauc aaagaagaag uccuagcaua cguaguccaa     1080

cucccacuau auggaguuau cgacacacca uguuggaaau uacacaccuc accauuaugc     1140

acaaccaaua caaaagaagg aucaaacaua ugccuuacac ggacagaccg cggaugguau     1200

ugugacaacg cuggcucagu cuccuuuuuc ccacaagcag aaacaugcaa aguacaauca     1260

aacagagucu uuugcgauac caugaacuca cuuacauuac caagcgaagu aaaucuuugu     1320

aacgucgaca ucuucaaucc uaaauaugac ugcaaaauca ugaccucaaa aacagacguu     1380

agcucuucag uaaucacuag cuuaggagca aucguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa auaaaaacag aggaaucaua aaaacauuuu caaacggaug cgauuaugua     1500

agcaacaaag gaguagauac uguaagcgua ggaaacacau uguacuaugu aaacaaacaa     1560

gaaggaaaau cacucuaugu aaaaggagaa ccuauaauca auuucuacga uccauuagug     1620

uucccaucag augaauuuga cgccucaaua ucacaaguua augaaaaaau aaaucaaucg     1680

cuagcauuca uacguaaauc agaugaauua cuacauaacg uaaacgcagg caaauccaca     1740

acaaauauca ugaucacaac aauuauaaua guaauaauag uaauacuacu aucacuaaua     1800

gccguaggac uccuacuaua cugcaaagca agaucuacuc caguaacccu cucaaaagau     1860

caacuaagcg gaauuaauaa caucgcauuc agcaacuaag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  930
<211>  2098
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  930
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuuaucc ucaaagccaa cgccaucacc accauccuca cagcaguaac cuuuugcuuc      240

gccucaggcc aaaauaucac agaagaauuu uaccagagua ccugcuccgc cguauccaaa      300

ggauaccuca gcgcgcuccg caccggcugg uacacuucag uaaucacaau cgaacuaucc      360

aacaucaaag aaaacaaaug caacggcacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaaugc cguaacagaa cuacaacugu uaaugcagag cacacccgcc      480

accaacaacc gcgcccgccg ggaacucccc cgauucauga acuacacacu caacaacgcc      540

aaaaagacga acgucacccu cagcaagaaa cgaaaacgca gauuccucgg uuuccuacua      600

ggcguaggcu cagcaauagc cuccggagua gccgucugca aaguccugca cuuagaaggc      660

gaagucaaca aaaucaaauc cgcccuacuc uccacgaaca aagccgucgu cucccugucc      720

aacggugucu ccguuuuaac cuucaaaguu cuggaccuca aaaacuacau agacaaacag      780

cuucucccca uccucaacaa acaauccugu agcaucucca acaucgaaac cgucauagaa      840

uuucaacaga aaaacaacag acugcucgaa aucacccgcg aguucuccgu caacgccggc      900

gucacgacuc ccgucuccac cuauaugcuc acgaacucgg aacuccuuuc ccuaaucaac      960

gacaugccga ucaccaacga ccaaaagaaa cucaugucaa acaacguaca aauuguccgc     1020

caacaaucau acuccaucau gugcauaauu aaagaagaag uccucgcaua cguaguccaa     1080

cucccccucu acggcgucau cgacaccccc ugcuggaaac uccacaccuc cccacucugc     1140

acaaccaaca ccaaagaagg cucaaacaua ugccuaacgc gcaccgaucg cgguugguac     1200

ugcgacaacg ccgguuccgu cagcuucuuc ccccaagcag agacaugcaa aguccaauca     1260

aaccgcgucu ucugcgacac caugaacuca cuaacccuuc caagcgaagu caaccucugc     1320

aacguugaca ucuucaaccc caaauacgac uguaaaauca ugaccuccaa gaccgacgua     1380

uccucuuccg ucaucacauc ccuaggcgcu aucguauccu gcuaugguaa aaccaaaugc     1440

accgccucca acaaaaaccg cggcaucauc aagacauuuu ccaacggcug cgacuacgug     1500

agcaacaaag gcgucgacac cgucuccgua ggcaacaccc ucuacuaugu aaacaaacaa     1560

gagggcaaau cacucuacgu caaaggggaa cccaucauca acuucuacga cccgcucgua     1620

uuccccagcg augaguucga cgccuccauc ucccagguca acgaaaagau aaaccaauca     1680

cucgcauuca uucguaaauc cgacgaacuc cuacacaacg ugaaugcagg caaaucgacc     1740

acuaacauca ugaucaccac caucaucauc gucaucauag ucauccuccu gucccuuauc     1800

gccgucgguc uuuuauuaua cugcaaagcc cgcagcaccc ccgucacccu cucuaaggac     1860

caacucagcg gcaucaauaa caucgcauuc ucuaacuaag gacuaguccc uguucccaga     1920

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2040

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2098


<210>  931
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  931
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  932
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  932
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcuccacgcc cgugacccug     1800

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  933
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  933
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  934
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  934
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggucuacacc cgugacgcuc     1800

agcaaggacc agcuguccgg gauaaacaau aucgcuuuuu caaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  935
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  935
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  936
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  936
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc gguccacccc cgugacgcuu     1800

agcaaggacc agcugucugg aauuaacaau aucgcuuuuu ccaacugagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  937
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  937
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uauuaauccu caaagcgaac gcuauuacua ccauucuaac agcagucaca      180

uucugcuucg ccucaggcca aaacauuaca gaagaauuuu accaaucaac augcucugcc      240

guaucaaaag gcuaccuauc cgcccuacga acaggcuggu acacaagcgu aauaacaauc      300

gaacuaucaa acauaaaaga aaacaaaugc aacgguacag acgccaaagu uaaacuaaua      360

aaacaagaac ucgauaaaua caaaaacgca guaacagaau uacaacuacu aaugcaauca      420

acaccugcaa caaacaauag agccaggaga gaauuaccuc gauucaugaa uuacacacuc      480

aauaacgcaa aaaaaaccaa cguuacacua ucaaaaaaaa gaaaacgacg auucuuagga      540

uuccuacucg gagucggauc agcaauagca ucuggcguug caguaugcaa aguauuacac      600

uuagaaggug aagucaauaa aauaaaaagc gcgcuacuaa guacaaacaa agcagucguc      660

ucccuaucaa acggagucuc aguccuaaca uucaaaguac ucgaccuaaa aaauuacaua      720

gauaaacaac uacuuccaau auuaaacaaa caauccugua gcaucagcaa uauagaaaca      780

guaauagaau uucaacaaaa aaacaaccga uuauuagaaa ucacucgaga auuuuccgua      840

aacgccgggg uaacaacucc agucucaacc uacaugcuaa ccaauucaga acuauugagc      900

uuaauaaacg acaugccaau aaccaacgac caaaaaaaac uaaugucuaa caauguucaa      960

aucgucagac aacaaaguua caguauaaug uguauaauca aagaagaagu ccuagcauac     1020

guaguccaac ucccacuaua uggaguuauc gacacaccau guuggaaauu acacaccuca     1080

ccauuaugca caaccaauac aaaagaagga ucaaacauau gccuuacacg gacagaccgc     1140

ggaugguauu gugacaacgc uggcucaguc uccuuuuucc cacaagcaga aacaugcaaa     1200

guacaaucaa acagagucuu uugcgauacc augaacucac uuacauuacc aagcgaagua     1260

aaucuuugua acgucgacau cuucaauccu aaauaugacu gcaaaaucau gaccucaaaa     1320

acagacguua gcucuucagu aaucacuagc uuaggagcaa ucguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa uaaaaacaga ggaaucauaa aaacauuuuc aaacggaugc     1440

gauuauguaa gcaacaaagg aguagauacu guaagcguag gaaacacauu guacuaugua     1500

aacaaacaag aaggaaaauc acucuaugua aaaggagaac cuauaaucaa uuucuacgau     1560

ccauuagugu ucccaucaga ugaauuugac gccucaauau cacaaguuaa ugaaaaaaua     1620

aaucaaucgc uagcauucau acguaaauca gaugaauuac uacauaacgu aaacgcaggc     1680

aaauccacaa caaauaucau gaucacaaca auuauaauag uaauaauagu aauacuacua     1740

ucacuaauag ccguaggacu ccuacuauac ugcaaagcaa gaucuacucc aguaacccuc     1800

ucaaaagauc aacuaagcgg aauuaauaac aucgcauuca gcaacuaagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  938
<211>  2047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  938
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuuauccu caaagccaac gccaucacca ccauccucac agcaguaacc      180

uuuugcuucg ccucaggcca aaauaucaca gaagaauuuu accagaguac cugcuccgcc      240

guauccaaag gauaccucag cgcgcuccgc accggcuggu acacuucagu aaucacaauc      300

gaacuaucca acaucaaaga aaacaaaugc aacggcaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaaugcc guaacagaac uacaacuguu aaugcagagc      420

acacccgcca ccaacaaccg cgcccgccgg gaacuccccc gauucaugaa cuacacacuc      480

aacaacgcca aaaagacgaa cgucacccuc agcaagaaac gaaaacgcag auuccucggu      540

uuccuacuag gcguaggcuc agcaauagcc uccggaguag ccgucugcaa aguccugcac      600

uuagaaggcg aagucaacaa aaucaaaucc gcccuacucu ccacgaacaa agccgucguc      660

ucccugucca acggugucuc cguuuuaacc uucaaaguuc uggaccucaa aaacuacaua      720

gacaaacagc uucuccccau ccucaacaaa caauccugua gcaucuccaa caucgaaacc      780

gucauagaau uucaacagaa aaacaacaga cugcucgaaa ucacccgcga guucuccguc      840

aacgccggcg ucacgacucc cgucuccacc uauaugcuca cgaacucgga acuccuuucc      900

cuaaucaacg acaugccgau caccaacgac caaaagaaac ucaugucaaa caacguacaa      960

auuguccgcc aacaaucaua cuccaucaug ugcauaauua aagaagaagu ccucgcauac     1020

guaguccaac ucccccucua cggcgucauc gacacccccu gcuggaaacu ccacaccucc     1080

ccacucugca caaccaacac caaagaaggc ucaaacauau gccuaacgcg caccgaucgc     1140

gguugguacu gcgacaacgc cgguuccguc agcuucuucc cccaagcaga gacaugcaaa     1200

guccaaucaa accgcgucuu cugcgacacc augaacucac uaacccuucc aagcgaaguc     1260

aaccucugca acguugacau cuucaacccc aaauacgacu guaaaaucau gaccuccaag     1320

accgacguau ccucuuccgu caucacaucc cuaggcgcua ucguauccug cuaugguaaa     1380

accaaaugca ccgccuccaa caaaaaccgc ggcaucauca agacauuuuc caacggcugc     1440

gacuacguga gcaacaaagg cgucgacacc gucuccguag gcaacacccu cuacuaugua     1500

aacaaacaag agggcaaauc acucuacguc aaaggggaac ccaucaucaa cuucuacgac     1560

ccgcucguau uccccagcga ugaguucgac gccuccaucu cccaggucaa cgaaaagaua     1620

aaccaaucac ucgcauucau ucguaaaucc gacgaacucc uacacaacgu gaaugcaggc     1680

aaaucgacca cuaacaucau gaucaccacc aucaucaucg ucaucauagu cauccuccug     1740

ucccuuaucg ccgucggucu uuuauuauac ugcaaagccc gcagcacccc cgucacccuc     1800

ucuaaggacc aacucagcgg caucaauaac aucgcauucu cuaacuaagg acuagucccu     1860

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2040

cagaauu                                                               2047


<210>  939
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  939
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  940
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  940
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcuc cacgcccgug     1740

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  941
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  941
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  942
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  942
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccagguc uacacccgug     1740

acgcucagca aggaccagcu guccgggaua aacaauaucg cuuuuucaaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  943
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  943
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  944
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  944
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccgguc cacccccgug     1740

acgcuuagca aggaccagcu gucuggaauu aacaauaucg cuuuuuccaa cugaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  945
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  945
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuauu aauccucaaa gcgaacgcua uuacuaccau ucuaacagca      120

gucacauucu gcuucgccuc aggccaaaac auuacagaag aauuuuacca aucaacaugc      180

ucugccguau caaaaggcua ccuauccgcc cuacgaacag gcugguacac aagcguaaua      240

acaaucgaac uaucaaacau aaaagaaaac aaaugcaacg guacagacgc caaaguuaaa      300

cuaauaaaac aagaacucga uaaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaucaacac cugcaacaaa caauagagcc aggagagaau uaccucgauu caugaauuac      420

acacucaaua acgcaaaaaa aaccaacguu acacuaucaa aaaaaagaaa acgacgauuc      480

uuaggauucc uacucggagu cggaucagca auagcaucug gcguugcagu augcaaagua      540

uuacacuuag aaggugaagu caauaaaaua aaaagcgcgc uacuaaguac aaacaaagca      600

gucgucuccc uaucaaacgg agucucaguc cuaacauuca aaguacucga ccuaaaaaau      660

uacauagaua aacaacuacu uccaauauua aacaaacaau ccuguagcau cagcaauaua      720

gaaacaguaa uagaauuuca acaaaaaaac aaccgauuau uagaaaucac ucgagaauuu      780

uccguaaacg ccgggguaac aacuccaguc ucaaccuaca ugcuaaccaa uucagaacua      840

uugagcuuaa uaaacgacau gccaauaacc aacgaccaaa aaaaacuaau gucuaacaau      900

guucaaaucg ucagacaaca aaguuacagu auaaugugua uaaucaaaga agaaguccua      960

gcauacguag uccaacuccc acuauaugga guuaucgaca caccauguug gaaauuacac     1020

accucaccau uaugcacaac caauacaaaa gaaggaucaa acauaugccu uacacggaca     1080

gaccgcggau gguauuguga caacgcuggc ucagucuccu uuuucccaca agcagaaaca     1140

ugcaaaguac aaucaaacag agucuuuugc gauaccauga acucacuuac auuaccaagc     1200

gaaguaaauc uuuguaacgu cgacaucuuc aauccuaaau augacugcaa aaucaugacc     1260

ucaaaaacag acguuagcuc uucaguaauc acuagcuuag gagcaaucgu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaauaaa aacagaggaa ucauaaaaac auuuucaaac     1380

ggaugcgauu auguaagcaa caaaggagua gauacuguaa gcguaggaaa cacauuguac     1440

uauguaaaca aacaagaagg aaaaucacuc uauguaaaag gagaaccuau aaucaauuuc     1500

uacgauccau uaguguuccc aucagaugaa uuugacgccu caauaucaca aguuaaugaa     1560

aaaauaaauc aaucgcuagc auucauacgu aaaucagaug aauuacuaca uaacguaaac     1620

gcaggcaaau ccacaacaaa uaucaugauc acaacaauua uaauaguaau aauaguaaua     1680

cuacuaucac uaauagccgu aggacuccua cuauacugca aagcaagauc uacuccagua     1740

acccucucaa aagaucaacu aagcggaauu aauaacaucg cauucagcaa cuaaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  946
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  946
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu uauccucaaa gccaacgcca ucaccaccau ccucacagca      120

guaaccuuuu gcuucgccuc aggccaaaau aucacagaag aauuuuacca gaguaccugc      180

uccgccguau ccaaaggaua ccucagcgcg cuccgcaccg gcugguacac uucaguaauc      240

acaaucgaac uauccaacau caaagaaaac aaaugcaacg gcaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aaugccguaa cagaacuaca acuguuaaug      360

cagagcacac ccgccaccaa caaccgcgcc cgccgggaac ucccccgauu caugaacuac      420

acacucaaca acgccaaaaa gacgaacguc acccucagca agaaacgaaa acgcagauuc      480

cucgguuucc uacuaggcgu aggcucagca auagccuccg gaguagccgu cugcaaaguc      540

cugcacuuag aaggcgaagu caacaaaauc aaauccgccc uacucuccac gaacaaagcc      600

gucgucuccc uguccaacgg ugucuccguu uuaaccuuca aaguucugga ccucaaaaac      660

uacauagaca aacagcuucu ccccauccuc aacaaacaau ccuguagcau cuccaacauc      720

gaaaccguca uagaauuuca acagaaaaac aacagacugc ucgaaaucac ccgcgaguuc      780

uccgucaacg ccggcgucac gacucccguc uccaccuaua ugcucacgaa cucggaacuc      840

cuuucccuaa ucaacgacau gccgaucacc aacgaccaaa agaaacucau gucaaacaac      900

guacaaauug uccgccaaca aucauacucc aucaugugca uaauuaaaga agaaguccuc      960

gcauacguag uccaacuccc ccucuacggc gucaucgaca cccccugcug gaaacuccac     1020

accuccccac ucugcacaac caacaccaaa gaaggcucaa acauaugccu aacgcgcacc     1080

gaucgcgguu gguacugcga caacgccggu uccgucagcu ucuuccccca agcagagaca     1140

ugcaaagucc aaucaaaccg cgucuucugc gacaccauga acucacuaac ccuuccaagc     1200

gaagucaacc ucugcaacgu ugacaucuuc aaccccaaau acgacuguaa aaucaugacc     1260

uccaagaccg acguauccuc uuccgucauc acaucccuag gcgcuaucgu auccugcuau     1320

gguaaaacca aaugcaccgc cuccaacaaa aaccgcggca ucaucaagac auuuuccaac     1380

ggcugcgacu acgugagcaa caaaggcguc gacaccgucu ccguaggcaa cacccucuac     1440

uauguaaaca aacaagaggg caaaucacuc uacgucaaag gggaacccau caucaacuuc     1500

uacgacccgc ucguauuccc cagcgaugag uucgacgccu ccaucuccca ggucaacgaa     1560

aagauaaacc aaucacucgc auucauucgu aaauccgacg aacuccuaca caacgugaau     1620

gcaggcaaau cgaccacuaa caucaugauc accaccauca ucaucgucau cauagucauc     1680

cuccuguccc uuaucgccgu cggucuuuua uuauacugca aagcccgcag cacccccguc     1740

acccucucua aggaccaacu cagcggcauc aauaacaucg cauucucuaa cuaaggacua     1800

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  947
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  947
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      660

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      720

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      780

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      900

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      960

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc     1020

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc     1080

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc     1140

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1200

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1260

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1320

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1500

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1620

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1680

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1800

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1860

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1920

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  948
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  948
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      660

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      720

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      780

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      900

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      960

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug     1080

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug     1140

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1200

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1260

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1320

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1440

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1500

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1620

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1680

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1740

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1800

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1860

aucgccgucg ggcugcuccu guacugcaag gcgcgcucca cgcccgugac ccugagcaag     1920

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  949
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  949
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      600

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      660

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      720

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      780

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      840

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      900

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      960

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc     1080

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc     1140

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1200

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1260

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1320

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1500

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1560

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1620

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1680

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1740

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1800

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1860

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1920

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  950
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  950
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      600

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      660

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      720

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      780

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      840

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      900

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      960

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc     1020

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua     1080

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug     1140

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1200

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1260

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1320

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1380

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1440

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1500

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1560

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1620

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1680

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1740

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1800

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1860

aucgcuguag gccuucuguu guacugcaag gccaggucua cacccgugac gcucagcaag     1920

gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  951
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  951
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      600

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      660

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      720

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      780

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      840

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      900

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      960

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug     1080

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug     1140

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1200

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1260

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1320

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1380

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1440

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1500

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1620

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1680

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1800

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1860

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1920

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  952
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  952
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      600

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      660

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      720

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      780

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      840

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      900

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      960

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc     1020

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug     1080

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc     1140

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1200

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1260

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1320

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1380

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1440

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1500

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1560

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1620

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1680

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1740

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1800

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1860

aucgcggucg ggcugcuccu guacugcaag gcccggucca cccccgugac gcuuagcaag     1920

gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu gaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  953
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  953
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc uaacagcagu cacauucugc      300

uucgccucag gccaaaacau uacagaagaa uuuuaccaau caacaugcuc ugccguauca      360

aaaggcuacc uauccgcccu acgaacaggc ugguacacaa gcguaauaac aaucgaacua      420

ucaaacauaa aagaaaacaa augcaacggu acagacgcca aaguuaaacu aauaaaacaa      480

gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aucaacaccu      540

gcaacaaaca auagagccag gagagaauua ccucgauuca ugaauuacac acucaauaac      600

gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac gacgauucuu aggauuccua      660

cucggagucg gaucagcaau agcaucuggc guugcaguau gcaaaguauu acacuuagaa      720

ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa acaaagcagu cgucucccua      780

ucaaacggag ucucaguccu aacauucaaa guacucgacc uaaaaaauua cauagauaaa      840

caacuacuuc caauauuaaa caaacaaucc uguagcauca gcaauauaga aacaguaaua      900

gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc gagaauuuuc cguaaacgcc      960

gggguaacaa cuccagucuc aaccuacaug cuaaccaauu cagaacuauu gagcuuaaua     1020

aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu cuaacaaugu ucaaaucguc     1080

agacaacaaa guuacaguau aauguguaua aucaaagaag aaguccuagc auacguaguc     1140

caacucccac uauauggagu uaucgacaca ccauguugga aauuacacac cucaccauua     1200

ugcacaacca auacaaaaga aggaucaaac auaugccuua cacggacaga ccgcggaugg     1260

uauugugaca acgcuggcuc agucuccuuu uucccacaag cagaaacaug caaaguacaa     1320

ucaaacagag ucuuuugcga uaccaugaac ucacuuacau uaccaagcga aguaaaucuu     1380

uguaacgucg acaucuucaa uccuaaauau gacugcaaaa ucaugaccuc aaaaacagac     1440

guuagcucuu caguaaucac uagcuuagga gcaaucguau caugcuacgg caaaacaaaa     1500

uguacagcau caaauaaaaa cagaggaauc auaaaaacau uuucaaacgg augcgauuau     1560

guaagcaaca aaggaguaga uacuguaagc guaggaaaca cauuguacua uguaaacaaa     1620

caagaaggaa aaucacucua uguaaaagga gaaccuauaa ucaauuucua cgauccauua     1680

guguucccau cagaugaauu ugacgccuca auaucacaag uuaaugaaaa aauaaaucaa     1740

ucgcuagcau ucauacguaa aucagaugaa uuacuacaua acguaaacgc aggcaaaucc     1800

acaacaaaua ucaugaucac aacaauuaua auaguaauaa uaguaauacu acuaucacua     1860

auagccguag gacuccuacu auacugcaaa gcaagaucua cuccaguaac ccucucaaaa     1920

gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu aaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  954
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  954
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuua uccucaaagc caacgccauc accaccaucc ucacagcagu aaccuuuugc      300

uucgccucag gccaaaauau cacagaagaa uuuuaccaga guaccugcuc cgccguaucc      360

aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu caguaaucac aaucgaacua      420

uccaacauca aagaaaacaa augcaacggc accgacgcga aagucaaacu caucaaacaa      480

gaacuagaca aauacaaaaa ugccguaaca gaacuacaac uguuaaugca gagcacaccc      540

gccaccaaca accgcgcccg ccgggaacuc ccccgauuca ugaacuacac acucaacaac      600

gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac gcagauuccu cgguuuccua      660

cuaggcguag gcucagcaau agccuccgga guagccgucu gcaaaguccu gcacuuagaa      720

ggcgaaguca acaaaaucaa auccgcccua cucuccacga acaaagccgu cgucucccug      780

uccaacggug ucuccguuuu aaccuucaaa guucuggacc ucaaaaacua cauagacaaa      840

cagcuucucc ccauccucaa caaacaaucc uguagcaucu ccaacaucga aaccgucaua      900

gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc gcgaguucuc cgucaacgcc      960

ggcgucacga cucccgucuc caccuauaug cucacgaacu cggaacuccu uucccuaauc     1020

aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaauuguc     1080

cgccaacaau cauacuccau caugugcaua auuaaagaag aaguccucgc auacguaguc     1140

caacuccccc ucuacggcgu caucgacacc cccugcugga aacuccacac cuccccacuc     1200

ugcacaacca acaccaaaga aggcucaaac auaugccuaa cgcgcaccga ucgcgguugg     1260

uacugcgaca acgccgguuc cgucagcuuc uucccccaag cagagacaug caaaguccaa     1320

ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc uuccaagcga agucaaccuc     1380

ugcaacguug acaucuucaa ccccaaauac gacuguaaaa ucaugaccuc caagaccgac     1440

guauccucuu ccgucaucac aucccuaggc gcuaucguau ccugcuaugg uaaaaccaaa     1500

ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau uuuccaacgg cugcgacuac     1560

gugagcaaca aaggcgucga caccgucucc guaggcaaca cccucuacua uguaaacaaa     1620

caagagggca aaucacucua cgucaaaggg gaacccauca ucaacuucua cgacccgcuc     1680

guauucccca gcgaugaguu cgacgccucc aucucccagg ucaacgaaaa gauaaaccaa     1740

ucacucgcau ucauucguaa auccgacgaa cuccuacaca acgugaaugc aggcaaaucg     1800

accacuaaca ucaugaucac caccaucauc aucgucauca uagucauccu ccugucccuu     1860

aucgccgucg gucuuuuauu auacugcaaa gcccgcagca cccccgucac ccucucuaag     1920

gaccaacuca gcggcaucaa uaacaucgca uucucuaacu aaggacuagu guccaccugu     1980

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  955
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  955
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  956
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  956
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      600

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      720

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      780

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug      960

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1020

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1440

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1560

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1680

aucgccgucg ggcugcuccu guacugcaag gcgcgcucca cgcccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  957
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  957
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  958
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  958
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      600

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      720

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      780

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua      900

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug      960

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1020

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1080

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1140

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1200

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1260

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1320

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1380

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1440

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1500

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1560

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1620

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1680

aucgcuguag gccuucuguu guacugcaag gccaggucua cacccgugac gcucagcaag     1740

gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  959
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  959
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  960
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  960
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      600

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      720

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      780

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug      900

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc      960

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1020

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1080

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1140

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1200

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1260

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1320

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1380

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1440

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1500

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1560

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1680

aucgcggucg ggcugcuccu guacugcaag gcccggucca cccccgugac gcuuagcaag     1740

gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  961
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  961
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc uaacagcagu cacauucugc      120

uucgccucag gccaaaacau uacagaagaa uuuuaccaau caacaugcuc ugccguauca      180

aaaggcuacc uauccgcccu acgaacaggc ugguacacaa gcguaauaac aaucgaacua      240

ucaaacauaa aagaaaacaa augcaacggu acagacgcca aaguuaaacu aauaaaacaa      300

gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aucaacaccu      360

gcaacaaaca auagagccag gagagaauua ccucgauuca ugaauuacac acucaauaac      420

gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac gacgauucuu aggauuccua      480

cucggagucg gaucagcaau agcaucuggc guugcaguau gcaaaguauu acacuuagaa      540

ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa acaaagcagu cgucucccua      600

ucaaacggag ucucaguccu aacauucaaa guacucgacc uaaaaaauua cauagauaaa      660

caacuacuuc caauauuaaa caaacaaucc uguagcauca gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc gagaauuuuc cguaaacgcc      780

gggguaacaa cuccagucuc aaccuacaug cuaaccaauu cagaacuauu gagcuuaaua      840

aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu cuaacaaugu ucaaaucguc      900

agacaacaaa guuacaguau aauguguaua aucaaagaag aaguccuagc auacguaguc      960

caacucccac uauauggagu uaucgacaca ccauguugga aauuacacac cucaccauua     1020

ugcacaacca auacaaaaga aggaucaaac auaugccuua cacggacaga ccgcggaugg     1080

uauugugaca acgcuggcuc agucuccuuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag ucuuuugcga uaccaugaac ucacuuacau uaccaagcga aguaaaucuu     1200

uguaacgucg acaucuucaa uccuaaauau gacugcaaaa ucaugaccuc aaaaacagac     1260

guuagcucuu caguaaucac uagcuuagga gcaaucguau caugcuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa cagaggaauc auaaaaacau uuucaaacgg augcgauuau     1380

guaagcaaca aaggaguaga uacuguaagc guaggaaaca cauuguacua uguaaacaaa     1440

caagaaggaa aaucacucua uguaaaagga gaaccuauaa ucaauuucua cgauccauua     1500

guguucccau cagaugaauu ugacgccuca auaucacaag uuaaugaaaa aauaaaucaa     1560

ucgcuagcau ucauacguaa aucagaugaa uuacuacaua acguaaacgc aggcaaaucc     1620

acaacaaaua ucaugaucac aacaauuaua auaguaauaa uaguaauacu acuaucacua     1680

auagccguag gacuccuacu auacugcaaa gcaagaucua cuccaguaac ccucucaaaa     1740

gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  962
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  962
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuua uccucaaagc caacgccauc accaccaucc ucacagcagu aaccuuuugc      120

uucgccucag gccaaaauau cacagaagaa uuuuaccaga guaccugcuc cgccguaucc      180

aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu caguaaucac aaucgaacua      240

uccaacauca aagaaaacaa augcaacggc accgacgcga aagucaaacu caucaaacaa      300

gaacuagaca aauacaaaaa ugccguaaca gaacuacaac uguuaaugca gagcacaccc      360

gccaccaaca accgcgcccg ccgggaacuc ccccgauuca ugaacuacac acucaacaac      420

gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac gcagauuccu cgguuuccua      480

cuaggcguag gcucagcaau agccuccgga guagccgucu gcaaaguccu gcacuuagaa      540

ggcgaaguca acaaaaucaa auccgcccua cucuccacga acaaagccgu cgucucccug      600

uccaacggug ucuccguuuu aaccuucaaa guucuggacc ucaaaaacua cauagacaaa      660

cagcuucucc ccauccucaa caaacaaucc uguagcaucu ccaacaucga aaccgucaua      720

gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacga cucccgucuc caccuauaug cucacgaacu cggaacuccu uucccuaauc      840

aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaauuguc      900

cgccaacaau cauacuccau caugugcaua auuaaagaag aaguccucgc auacguaguc      960

caacuccccc ucuacggcgu caucgacacc cccugcugga aacuccacac cuccccacuc     1020

ugcacaacca acaccaaaga aggcucaaac auaugccuaa cgcgcaccga ucgcgguugg     1080

uacugcgaca acgccgguuc cgucagcuuc uucccccaag cagagacaug caaaguccaa     1140

ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc uuccaagcga agucaaccuc     1200

ugcaacguug acaucuucaa ccccaaauac gacuguaaaa ucaugaccuc caagaccgac     1260

guauccucuu ccgucaucac aucccuaggc gcuaucguau ccugcuaugg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau uuuccaacgg cugcgacuac     1380

gugagcaaca aaggcgucga caccgucucc guaggcaaca cccucuacua uguaaacaaa     1440

caagagggca aaucacucua cgucaaaggg gaacccauca ucaacuucua cgacccgcuc     1500

guauucccca gcgaugaguu cgacgccucc aucucccagg ucaacgaaaa gauaaaccaa     1560

ucacucgcau ucauucguaa auccgacgaa cuccuacaca acgugaaugc aggcaaaucg     1620

accacuaaca ucaugaucac caccaucauc aucgucauca uagucauccu ccugucccuu     1680

aucgccgucg gucuuuuauu auacugcaaa gcccgcagca cccccgucac ccucucuaag     1740

gaccaacuca gcggcaucaa uaacaucgca uucucuaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  963
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  963
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  964
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  964
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcucca     1740

cgcccgugac ccugagcaag gaccagcucu ccggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  965
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  965
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  966
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  966
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggucua     1740

cacccgugac gcucagcaag gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  967
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  967
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  968
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  968
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggucca     1740

cccccgugac gcuuagcaag gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu     1800

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  969
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  969
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc      120

uaacagcagu cacauucugc uucgccucag gccaaaacau uacagaagaa uuuuaccaau      180

caacaugcuc ugccguauca aaaggcuacc uauccgcccu acgaacaggc ugguacacaa      240

gcguaauaac aaucgaacua ucaaacauaa aagaaaacaa augcaacggu acagacgcca      300

aaguuaaacu aauaaaacaa gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aucaacaccu gcaacaaaca auagagccag gagagaauua ccucgauuca      420

ugaauuacac acucaauaac gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac      480

gacgauucuu aggauuccua cucggagucg gaucagcaau agcaucuggc guugcaguau      540

gcaaaguauu acacuuagaa ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa      600

acaaagcagu cgucucccua ucaaacggag ucucaguccu aacauucaaa guacucgacc      660

uaaaaaauua cauagauaaa caacuacuuc caauauuaaa caaacaaucc uguagcauca      720

gcaauauaga aacaguaaua gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc      780

gagaauuuuc cguaaacgcc gggguaacaa cuccagucuc aaccuacaug cuaaccaauu      840

cagaacuauu gagcuuaaua aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu      900

cuaacaaugu ucaaaucguc agacaacaaa guuacaguau aauguguaua aucaaagaag      960

aaguccuagc auacguaguc caacucccac uauauggagu uaucgacaca ccauguugga     1020

aauuacacac cucaccauua ugcacaacca auacaaaaga aggaucaaac auaugccuua     1080

cacggacaga ccgcggaugg uauugugaca acgcuggcuc agucuccuuu uucccacaag     1140

cagaaacaug caaaguacaa ucaaacagag ucuuuugcga uaccaugaac ucacuuacau     1200

uaccaagcga aguaaaucuu uguaacgucg acaucuucaa uccuaaauau gacugcaaaa     1260

ucaugaccuc aaaaacagac guuagcucuu caguaaucac uagcuuagga gcaaucguau     1320

caugcuacgg caaaacaaaa uguacagcau caaauaaaaa cagaggaauc auaaaaacau     1380

uuucaaacgg augcgauuau guaagcaaca aaggaguaga uacuguaagc guaggaaaca     1440

cauuguacua uguaaacaaa caagaaggaa aaucacucua uguaaaagga gaaccuauaa     1500

ucaauuucua cgauccauua guguucccau cagaugaauu ugacgccuca auaucacaag     1560

uuaaugaaaa aauaaaucaa ucgcuagcau ucauacguaa aucagaugaa uuacuacaua     1620

acguaaacgc aggcaaaucc acaacaaaua ucaugaucac aacaauuaua auaguaauaa     1680

uaguaauacu acuaucacua auagccguag gacuccuacu auacugcaaa gcaagaucua     1740

cuccaguaac ccucucaaaa gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu     1800

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  970
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  970
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuua uccucaaagc caacgccauc accaccaucc      120

ucacagcagu aaccuuuugc uucgccucag gccaaaauau cacagaagaa uuuuaccaga      180

guaccugcuc cgccguaucc aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu      240

caguaaucac aaucgaacua uccaacauca aagaaaacaa augcaacggc accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa ugccguaaca gaacuacaac      360

uguuaaugca gagcacaccc gccaccaaca accgcgcccg ccgggaacuc ccccgauuca      420

ugaacuacac acucaacaac gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac      480

gcagauuccu cgguuuccua cuaggcguag gcucagcaau agccuccgga guagccgucu      540

gcaaaguccu gcacuuagaa ggcgaaguca acaaaaucaa auccgcccua cucuccacga      600

acaaagccgu cgucucccug uccaacggug ucuccguuuu aaccuucaaa guucuggacc      660

ucaaaaacua cauagacaaa cagcuucucc ccauccucaa caaacaaucc uguagcaucu      720

ccaacaucga aaccgucaua gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacga cucccgucuc caccuauaug cucacgaacu      840

cggaacuccu uucccuaauc aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu      900

caaacaacgu acaaauuguc cgccaacaau cauacuccau caugugcaua auuaaagaag      960

aaguccucgc auacguaguc caacuccccc ucuacggcgu caucgacacc cccugcugga     1020

aacuccacac cuccccacuc ugcacaacca acaccaaaga aggcucaaac auaugccuaa     1080

cgcgcaccga ucgcgguugg uacugcgaca acgccgguuc cgucagcuuc uucccccaag     1140

cagagacaug caaaguccaa ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc     1200

uuccaagcga agucaaccuc ugcaacguug acaucuucaa ccccaaauac gacuguaaaa     1260

ucaugaccuc caagaccgac guauccucuu ccgucaucac aucccuaggc gcuaucguau     1320

ccugcuaugg uaaaaccaaa ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau     1380

uuuccaacgg cugcgacuac gugagcaaca aaggcgucga caccgucucc guaggcaaca     1440

cccucuacua uguaaacaaa caagagggca aaucacucua cgucaaaggg gaacccauca     1500

ucaacuucua cgacccgcuc guauucccca gcgaugaguu cgacgccucc aucucccagg     1560

ucaacgaaaa gauaaaccaa ucacucgcau ucauucguaa auccgacgaa cuccuacaca     1620

acgugaaugc aggcaaaucg accacuaaca ucaugaucac caccaucauc aucgucauca     1680

uagucauccu ccugucccuu aucgccgucg gucuuuuauu auacugcaaa gcccgcagca     1740

cccccgucac ccucucuaag gaccaacuca gcggcaucaa uaacaucgca uucucuaacu     1800

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1860

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  971
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  971
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  972
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  972
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcucca     1740

cgcccgugac ccugagcaag gaccagcucu ccggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  973
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  973
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  974
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  974
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggucua     1740

cacccgugac gcucagcaag gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  975
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  975
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  976
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  976
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggucca     1740

cccccgugac gcuuagcaag gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu     1800

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  977
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  977
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc      120

uaacagcagu cacauucugc uucgccucag gccaaaacau uacagaagaa uuuuaccaau      180

caacaugcuc ugccguauca aaaggcuacc uauccgcccu acgaacaggc ugguacacaa      240

gcguaauaac aaucgaacua ucaaacauaa aagaaaacaa augcaacggu acagacgcca      300

aaguuaaacu aauaaaacaa gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aucaacaccu gcaacaaaca auagagccag gagagaauua ccucgauuca      420

ugaauuacac acucaauaac gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac      480

gacgauucuu aggauuccua cucggagucg gaucagcaau agcaucuggc guugcaguau      540

gcaaaguauu acacuuagaa ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa      600

acaaagcagu cgucucccua ucaaacggag ucucaguccu aacauucaaa guacucgacc      660

uaaaaaauua cauagauaaa caacuacuuc caauauuaaa caaacaaucc uguagcauca      720

gcaauauaga aacaguaaua gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc      780

gagaauuuuc cguaaacgcc gggguaacaa cuccagucuc aaccuacaug cuaaccaauu      840

cagaacuauu gagcuuaaua aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu      900

cuaacaaugu ucaaaucguc agacaacaaa guuacaguau aauguguaua aucaaagaag      960

aaguccuagc auacguaguc caacucccac uauauggagu uaucgacaca ccauguugga     1020

aauuacacac cucaccauua ugcacaacca auacaaaaga aggaucaaac auaugccuua     1080

cacggacaga ccgcggaugg uauugugaca acgcuggcuc agucuccuuu uucccacaag     1140

cagaaacaug caaaguacaa ucaaacagag ucuuuugcga uaccaugaac ucacuuacau     1200

uaccaagcga aguaaaucuu uguaacgucg acaucuucaa uccuaaauau gacugcaaaa     1260

ucaugaccuc aaaaacagac guuagcucuu caguaaucac uagcuuagga gcaaucguau     1320

caugcuacgg caaaacaaaa uguacagcau caaauaaaaa cagaggaauc auaaaaacau     1380

uuucaaacgg augcgauuau guaagcaaca aaggaguaga uacuguaagc guaggaaaca     1440

cauuguacua uguaaacaaa caagaaggaa aaucacucua uguaaaagga gaaccuauaa     1500

ucaauuucua cgauccauua guguucccau cagaugaauu ugacgccuca auaucacaag     1560

uuaaugaaaa aauaaaucaa ucgcuagcau ucauacguaa aucagaugaa uuacuacaua     1620

acguaaacgc aggcaaaucc acaacaaaua ucaugaucac aacaauuaua auaguaauaa     1680

uaguaauacu acuaucacua auagccguag gacuccuacu auacugcaaa gcaagaucua     1740

cuccaguaac ccucucaaaa gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu     1800

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  978
<211>  2065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  978
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuua uccucaaagc caacgccauc accaccaucc      120

ucacagcagu aaccuuuugc uucgccucag gccaaaauau cacagaagaa uuuuaccaga      180

guaccugcuc cgccguaucc aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu      240

caguaaucac aaucgaacua uccaacauca aagaaaacaa augcaacggc accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa ugccguaaca gaacuacaac      360

uguuaaugca gagcacaccc gccaccaaca accgcgcccg ccgggaacuc ccccgauuca      420

ugaacuacac acucaacaac gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac      480

gcagauuccu cgguuuccua cuaggcguag gcucagcaau agccuccgga guagccgucu      540

gcaaaguccu gcacuuagaa ggcgaaguca acaaaaucaa auccgcccua cucuccacga      600

acaaagccgu cgucucccug uccaacggug ucuccguuuu aaccuucaaa guucuggacc      660

ucaaaaacua cauagacaaa cagcuucucc ccauccucaa caaacaaucc uguagcaucu      720

ccaacaucga aaccgucaua gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacga cucccgucuc caccuauaug cucacgaacu      840

cggaacuccu uucccuaauc aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu      900

caaacaacgu acaaauuguc cgccaacaau cauacuccau caugugcaua auuaaagaag      960

aaguccucgc auacguaguc caacuccccc ucuacggcgu caucgacacc cccugcugga     1020

aacuccacac cuccccacuc ugcacaacca acaccaaaga aggcucaaac auaugccuaa     1080

cgcgcaccga ucgcgguugg uacugcgaca acgccgguuc cgucagcuuc uucccccaag     1140

cagagacaug caaaguccaa ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc     1200

uuccaagcga agucaaccuc ugcaacguug acaucuucaa ccccaaauac gacuguaaaa     1260

ucaugaccuc caagaccgac guauccucuu ccgucaucac aucccuaggc gcuaucguau     1320

ccugcuaugg uaaaaccaaa ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau     1380

uuuccaacgg cugcgacuac gugagcaaca aaggcgucga caccgucucc guaggcaaca     1440

cccucuacua uguaaacaaa caagagggca aaucacucua cgucaaaggg gaacccauca     1500

ucaacuucua cgacccgcuc guauucccca gcgaugaguu cgacgccucc aucucccagg     1560

ucaacgaaaa gauaaaccaa ucacucgcau ucauucguaa auccgacgaa cuccuacaca     1620

acgugaaugc aggcaaaucg accacuaaca ucaugaucac caccaucauc aucgucauca     1680

uagucauccu ccugucccuu aucgccgucg gucuuuuauu auacugcaaa gcccgcagca     1740

cccccgucac ccucucuaag gaccaacuca gcggcaucaa uaacaucgca uucucuaacu     1800

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1860

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1920

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2040

ggcucuuuuc agagccacca gaauu                                           2065


<210>  979
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  979
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  980
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  980
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcuccacgcc cgugacccug     1800

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  981
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  981
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  982
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  982
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggucuacacc cgugacgcuc     1800

agcaaggacc agcuguccgg gauaaacaau aucgcuuuuu caaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  983
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  983
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  984
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  984
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc gguccacccc cgugacgcuu     1800

agcaaggacc agcugucugg aauuaacaau aucgcuuuuu ccaacugagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  985
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  985
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uauuaauccu caaagcgaac gcuauuacua ccauucuaac agcagucaca      180

uucugcuucg ccucaggcca aaacauuaca gaagaauuuu accaaucaac augcucugcc      240

guaucaaaag gcuaccuauc cgcccuacga acaggcuggu acacaagcgu aauaacaauc      300

gaacuaucaa acauaaaaga aaacaaaugc aacgguacag acgccaaagu uaaacuaaua      360

aaacaagaac ucgauaaaua caaaaacgca guaacagaau uacaacuacu aaugcaauca      420

acaccugcaa caaacaauag agccaggaga gaauuaccuc gauucaugaa uuacacacuc      480

aauaacgcaa aaaaaaccaa cguuacacua ucaaaaaaaa gaaaacgacg auucuuagga      540

uuccuacucg gagucggauc agcaauagca ucuggcguug caguaugcaa aguauuacac      600

uuagaaggug aagucaauaa aauaaaaagc gcgcuacuaa guacaaacaa agcagucguc      660

ucccuaucaa acggagucuc aguccuaaca uucaaaguac ucgaccuaaa aaauuacaua      720

gauaaacaac uacuuccaau auuaaacaaa caauccugua gcaucagcaa uauagaaaca      780

guaauagaau uucaacaaaa aaacaaccga uuauuagaaa ucacucgaga auuuuccgua      840

aacgccgggg uaacaacucc agucucaacc uacaugcuaa ccaauucaga acuauugagc      900

uuaauaaacg acaugccaau aaccaacgac caaaaaaaac uaaugucuaa caauguucaa      960

aucgucagac aacaaaguua caguauaaug uguauaauca aagaagaagu ccuagcauac     1020

guaguccaac ucccacuaua uggaguuauc gacacaccau guuggaaauu acacaccuca     1080

ccauuaugca caaccaauac aaaagaagga ucaaacauau gccuuacacg gacagaccgc     1140

ggaugguauu gugacaacgc uggcucaguc uccuuuuucc cacaagcaga aacaugcaaa     1200

guacaaucaa acagagucuu uugcgauacc augaacucac uuacauuacc aagcgaagua     1260

aaucuuugua acgucgacau cuucaauccu aaauaugacu gcaaaaucau gaccucaaaa     1320

acagacguua gcucuucagu aaucacuagc uuaggagcaa ucguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa uaaaaacaga ggaaucauaa aaacauuuuc aaacggaugc     1440

gauuauguaa gcaacaaagg aguagauacu guaagcguag gaaacacauu guacuaugua     1500

aacaaacaag aaggaaaauc acucuaugua aaaggagaac cuauaaucaa uuucuacgau     1560

ccauuagugu ucccaucaga ugaauuugac gccucaauau cacaaguuaa ugaaaaaaua     1620

aaucaaucgc uagcauucau acguaaauca gaugaauuac uacauaacgu aaacgcaggc     1680

aaauccacaa caaauaucau gaucacaaca auuauaauag uaauaauagu aauacuacua     1740

ucacuaauag ccguaggacu ccuacuauac ugcaaagcaa gaucuacucc aguaacccuc     1800

ucaaaagauc aacuaagcgg aauuaauaac aucgcauuca gcaacuaagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  986
<211>  2127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  986
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuuauccu caaagccaac gccaucacca ccauccucac agcaguaacc      180

uuuugcuucg ccucaggcca aaauaucaca gaagaauuuu accagaguac cugcuccgcc      240

guauccaaag gauaccucag cgcgcuccgc accggcuggu acacuucagu aaucacaauc      300

gaacuaucca acaucaaaga aaacaaaugc aacggcaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaaugcc guaacagaac uacaacuguu aaugcagagc      420

acacccgcca ccaacaaccg cgcccgccgg gaacuccccc gauucaugaa cuacacacuc      480

aacaacgcca aaaagacgaa cgucacccuc agcaagaaac gaaaacgcag auuccucggu      540

uuccuacuag gcguaggcuc agcaauagcc uccggaguag ccgucugcaa aguccugcac      600

uuagaaggcg aagucaacaa aaucaaaucc gcccuacucu ccacgaacaa agccgucguc      660

ucccugucca acggugucuc cguuuuaacc uucaaaguuc uggaccucaa aaacuacaua      720

gacaaacagc uucuccccau ccucaacaaa caauccugua gcaucuccaa caucgaaacc      780

gucauagaau uucaacagaa aaacaacaga cugcucgaaa ucacccgcga guucuccguc      840

aacgccggcg ucacgacucc cgucuccacc uauaugcuca cgaacucgga acuccuuucc      900

cuaaucaacg acaugccgau caccaacgac caaaagaaac ucaugucaaa caacguacaa      960

auuguccgcc aacaaucaua cuccaucaug ugcauaauua aagaagaagu ccucgcauac     1020

guaguccaac ucccccucua cggcgucauc gacacccccu gcuggaaacu ccacaccucc     1080

ccacucugca caaccaacac caaagaaggc ucaaacauau gccuaacgcg caccgaucgc     1140

gguugguacu gcgacaacgc cgguuccguc agcuucuucc cccaagcaga gacaugcaaa     1200

guccaaucaa accgcgucuu cugcgacacc augaacucac uaacccuucc aagcgaaguc     1260

aaccucugca acguugacau cuucaacccc aaauacgacu guaaaaucau gaccuccaag     1320

accgacguau ccucuuccgu caucacaucc cuaggcgcua ucguauccug cuaugguaaa     1380

accaaaugca ccgccuccaa caaaaaccgc ggcaucauca agacauuuuc caacggcugc     1440

gacuacguga gcaacaaagg cgucgacacc gucuccguag gcaacacccu cuacuaugua     1500

aacaaacaag agggcaaauc acucuacguc aaaggggaac ccaucaucaa cuucuacgac     1560

ccgcucguau uccccagcga ugaguucgac gccuccaucu cccaggucaa cgaaaagaua     1620

aaccaaucac ucgcauucau ucguaaaucc gacgaacucc uacacaacgu gaaugcaggc     1680

aaaucgacca cuaacaucau gaucaccacc aucaucaucg ucaucauagu cauccuccug     1740

ucccuuaucg ccgucggucu uuuauuauac ugcaaagccc gcagcacccc cgucacccuc     1800

ucuaaggacc aacucagcgg caucaauaac aucgcauucu cuaacuaagg acuaguacug     1860

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1920

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1980

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2100

aaggcucuuu ucagagccac cagaauu                                         2127


<210>  987
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  987
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  988
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  988
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcuccac gcccgugacc cugagcaagg accagcucuc cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  989
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  989
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  990
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  990
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggucuac acccgugacg cucagcaagg accagcuguc cgggauaaac     1800

aauaucgcuu uuucaaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  991
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  991
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  992
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  992
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccgguccac ccccgugacg cuuagcaagg accagcuguc uggaauuaac     1800

aauaucgcuu uuuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  993
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  993
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuauuaau ccucaaagcg      120

aacgcuauua cuaccauucu aacagcaguc acauucugcu ucgccucagg ccaaaacauu      180

acagaagaau uuuaccaauc aacaugcucu gccguaucaa aaggcuaccu auccgcccua      240

cgaacaggcu gguacacaag cguaauaaca aucgaacuau caaacauaaa agaaaacaaa      300

ugcaacggua cagacgccaa aguuaaacua auaaaacaag aacucgauaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa ucaacaccug caacaaacaa uagagccagg      420

agagaauuac cucgauucau gaauuacaca cucaauaacg caaaaaaaac caacguuaca      480

cuaucaaaaa aaagaaaacg acgauucuua ggauuccuac ucggagucgg aucagcaaua      540

gcaucuggcg uugcaguaug caaaguauua cacuuagaag gugaagucaa uaaaauaaaa      600

agcgcgcuac uaaguacaaa caaagcaguc gucucccuau caaacggagu cucaguccua      660

acauucaaag uacucgaccu aaaaaauuac auagauaaac aacuacuucc aauauuaaac      720

aaacaauccu guagcaucag caauauagaa acaguaauag aauuucaaca aaaaaacaac      780

cgauuauuag aaaucacucg agaauuuucc guaaacgccg ggguaacaac uccagucuca      840

accuacaugc uaaccaauuc agaacuauug agcuuaauaa acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaauguc uaacaauguu caaaucguca gacaacaaag uuacaguaua      960

auguguauaa ucaaagaaga aguccuagca uacguagucc aacucccacu auauggaguu     1020

aucgacacac cauguuggaa auuacacacc ucaccauuau gcacaaccaa uacaaaagaa     1080

ggaucaaaca uaugccuuac acggacagac cgcggauggu auugugacaa cgcuggcuca     1140

gucuccuuuu ucccacaagc agaaacaugc aaaguacaau caaacagagu cuuuugcgau     1200

accaugaacu cacuuacauu accaagcgaa guaaaucuuu guaacgucga caucuucaau     1260

ccuaaauaug acugcaaaau caugaccuca aaaacagacg uuagcucuuc aguaaucacu     1320

agcuuaggag caaucguauc augcuacggc aaaacaaaau guacagcauc aaauaaaaac     1380

agaggaauca uaaaaacauu uucaaacgga ugcgauuaug uaagcaacaa aggaguagau     1440

acuguaagcg uaggaaacac auuguacuau guaaacaaac aagaaggaaa aucacucuau     1500

guaaaaggag aaccuauaau caauuucuac gauccauuag uguucccauc agaugaauuu     1560

gacgccucaa uaucacaagu uaaugaaaaa auaaaucaau cgcuagcauu cauacguaaa     1620

ucagaugaau uacuacauaa cguaaacgca ggcaaaucca caacaaauau caugaucaca     1680

acaauuauaa uaguaauaau aguaauacua cuaucacuaa uagccguagg acuccuacua     1740

uacugcaaag caagaucuac uccaguaacc cucucaaaag aucaacuaag cggaauuaau     1800

aacaucgcau ucagcaacua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  994
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  994
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuuau ccucaaagcc      120

aacgccauca ccaccauccu cacagcagua accuuuugcu ucgccucagg ccaaaauauc      180

acagaagaau uuuaccagag uaccugcucc gccguaucca aaggauaccu cagcgcgcuc      240

cgcaccggcu gguacacuuc aguaaucaca aucgaacuau ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa auacaaaaau      360

gccguaacag aacuacaacu guuaaugcag agcacacccg ccaccaacaa ccgcgcccgc      420

cgggaacucc cccgauucau gaacuacaca cucaacaacg ccaaaaagac gaacgucacc      480

cucagcaaga aacgaaaacg cagauuccuc gguuuccuac uaggcguagg cucagcaaua      540

gccuccggag uagccgucug caaaguccug cacuuagaag gcgaagucaa caaaaucaaa      600

uccgcccuac ucuccacgaa caaagccguc gucucccugu ccaacggugu cuccguuuua      660

accuucaaag uucuggaccu caaaaacuac auagacaaac agcuucuccc cauccucaac      720

aaacaauccu guagcaucuc caacaucgaa accgucauag aauuucaaca gaaaaacaac      780

agacugcucg aaaucacccg cgaguucucc gucaacgccg gcgucacgac ucccgucucc      840

accuauaugc ucacgaacuc ggaacuccuu ucccuaauca acgacaugcc gaucaccaac      900

gaccaaaaga aacucauguc aaacaacgua caaauugucc gccaacaauc auacuccauc      960

augugcauaa uuaaagaaga aguccucgca uacguagucc aacucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa acuccacacc uccccacucu gcacaaccaa caccaaagaa     1080

ggcucaaaca uaugccuaac gcgcaccgau cgcgguuggu acugcgacaa cgccgguucc     1140

gucagcuucu ucccccaagc agagacaugc aaaguccaau caaaccgcgu cuucugcgac     1200

accaugaacu cacuaacccu uccaagcgaa gucaaccucu gcaacguuga caucuucaac     1260

cccaaauacg acuguaaaau caugaccucc aagaccgacg uauccucuuc cgucaucaca     1320

ucccuaggcg cuaucguauc cugcuauggu aaaaccaaau gcaccgccuc caacaaaaac     1380

cgcggcauca ucaagacauu uuccaacggc ugcgacuacg ugagcaacaa aggcgucgac     1440

accgucuccg uaggcaacac ccucuacuau guaaacaaac aagagggcaa aucacucuac     1500

gucaaagggg aacccaucau caacuucuac gacccgcucg uauuccccag cgaugaguuc     1560

gacgccucca ucucccaggu caacgaaaag auaaaccaau cacucgcauu cauucguaaa     1620

uccgacgaac uccuacacaa cgugaaugca ggcaaaucga ccacuaacau caugaucacc     1680

accaucauca ucgucaucau agucauccuc cugucccuua ucgccgucgg ucuuuuauua     1740

uacugcaaag cccgcagcac ccccgucacc cucucuaagg accaacucag cggcaucaau     1800

aacaucgcau ucucuaacua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1860

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  995
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  995
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  996
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  996
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcuccacgcc cgugacccug     1800

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  997
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  997
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  998
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  998
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggucuacacc cgugacgcuc     1800

agcaaggacc agcuguccgg gauaaacaau aucgcuuuuu caaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  999
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  999
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  1000
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1000
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc gguccacccc cgugacgcuu     1800

agcaaggacc agcugucugg aauuaacaau aucgcuuuuu ccaacugagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  1001
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1001
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uauuaauccu caaagcgaac gcuauuacua ccauucuaac agcagucaca      180

uucugcuucg ccucaggcca aaacauuaca gaagaauuuu accaaucaac augcucugcc      240

guaucaaaag gcuaccuauc cgcccuacga acaggcuggu acacaagcgu aauaacaauc      300

gaacuaucaa acauaaaaga aaacaaaugc aacgguacag acgccaaagu uaaacuaaua      360

aaacaagaac ucgauaaaua caaaaacgca guaacagaau uacaacuacu aaugcaauca      420

acaccugcaa caaacaauag agccaggaga gaauuaccuc gauucaugaa uuacacacuc      480

aauaacgcaa aaaaaaccaa cguuacacua ucaaaaaaaa gaaaacgacg auucuuagga      540

uuccuacucg gagucggauc agcaauagca ucuggcguug caguaugcaa aguauuacac      600

uuagaaggug aagucaauaa aauaaaaagc gcgcuacuaa guacaaacaa agcagucguc      660

ucccuaucaa acggagucuc aguccuaaca uucaaaguac ucgaccuaaa aaauuacaua      720

gauaaacaac uacuuccaau auuaaacaaa caauccugua gcaucagcaa uauagaaaca      780

guaauagaau uucaacaaaa aaacaaccga uuauuagaaa ucacucgaga auuuuccgua      840

aacgccgggg uaacaacucc agucucaacc uacaugcuaa ccaauucaga acuauugagc      900

uuaauaaacg acaugccaau aaccaacgac caaaaaaaac uaaugucuaa caauguucaa      960

aucgucagac aacaaaguua caguauaaug uguauaauca aagaagaagu ccuagcauac     1020

guaguccaac ucccacuaua uggaguuauc gacacaccau guuggaaauu acacaccuca     1080

ccauuaugca caaccaauac aaaagaagga ucaaacauau gccuuacacg gacagaccgc     1140

ggaugguauu gugacaacgc uggcucaguc uccuuuuucc cacaagcaga aacaugcaaa     1200

guacaaucaa acagagucuu uugcgauacc augaacucac uuacauuacc aagcgaagua     1260

aaucuuugua acgucgacau cuucaauccu aaauaugacu gcaaaaucau gaccucaaaa     1320

acagacguua gcucuucagu aaucacuagc uuaggagcaa ucguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa uaaaaacaga ggaaucauaa aaacauuuuc aaacggaugc     1440

gauuauguaa gcaacaaagg aguagauacu guaagcguag gaaacacauu guacuaugua     1500

aacaaacaag aaggaaaauc acucuaugua aaaggagaac cuauaaucaa uuucuacgau     1560

ccauuagugu ucccaucaga ugaauuugac gccucaauau cacaaguuaa ugaaaaaaua     1620

aaucaaucgc uagcauucau acguaaauca gaugaauuac uacauaacgu aaacgcaggc     1680

aaauccacaa caaauaucau gaucacaaca auuauaauag uaauaauagu aauacuacua     1740

ucacuaauag ccguaggacu ccuacuauac ugcaaagcaa gaucuacucc aguaacccuc     1800

ucaaaagauc aacuaagcgg aauuaauaac aucgcauuca gcaacuaagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  1002
<211>  2123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1002
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuuauccu caaagccaac gccaucacca ccauccucac agcaguaacc      180

uuuugcuucg ccucaggcca aaauaucaca gaagaauuuu accagaguac cugcuccgcc      240

guauccaaag gauaccucag cgcgcuccgc accggcuggu acacuucagu aaucacaauc      300

gaacuaucca acaucaaaga aaacaaaugc aacggcaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaaugcc guaacagaac uacaacuguu aaugcagagc      420

acacccgcca ccaacaaccg cgcccgccgg gaacuccccc gauucaugaa cuacacacuc      480

aacaacgcca aaaagacgaa cgucacccuc agcaagaaac gaaaacgcag auuccucggu      540

uuccuacuag gcguaggcuc agcaauagcc uccggaguag ccgucugcaa aguccugcac      600

uuagaaggcg aagucaacaa aaucaaaucc gcccuacucu ccacgaacaa agccgucguc      660

ucccugucca acggugucuc cguuuuaacc uucaaaguuc uggaccucaa aaacuacaua      720

gacaaacagc uucuccccau ccucaacaaa caauccugua gcaucuccaa caucgaaacc      780

gucauagaau uucaacagaa aaacaacaga cugcucgaaa ucacccgcga guucuccguc      840

aacgccggcg ucacgacucc cgucuccacc uauaugcuca cgaacucgga acuccuuucc      900

cuaaucaacg acaugccgau caccaacgac caaaagaaac ucaugucaaa caacguacaa      960

auuguccgcc aacaaucaua cuccaucaug ugcauaauua aagaagaagu ccucgcauac     1020

guaguccaac ucccccucua cggcgucauc gacacccccu gcuggaaacu ccacaccucc     1080

ccacucugca caaccaacac caaagaaggc ucaaacauau gccuaacgcg caccgaucgc     1140

gguugguacu gcgacaacgc cgguuccguc agcuucuucc cccaagcaga gacaugcaaa     1200

guccaaucaa accgcgucuu cugcgacacc augaacucac uaacccuucc aagcgaaguc     1260

aaccucugca acguugacau cuucaacccc aaauacgacu guaaaaucau gaccuccaag     1320

accgacguau ccucuuccgu caucacaucc cuaggcgcua ucguauccug cuaugguaaa     1380

accaaaugca ccgccuccaa caaaaaccgc ggcaucauca agacauuuuc caacggcugc     1440

gacuacguga gcaacaaagg cgucgacacc gucuccguag gcaacacccu cuacuaugua     1500

aacaaacaag agggcaaauc acucuacguc aaaggggaac ccaucaucaa cuucuacgac     1560

ccgcucguau uccccagcga ugaguucgac gccuccaucu cccaggucaa cgaaaagaua     1620

aaccaaucac ucgcauucau ucguaaaucc gacgaacucc uacacaacgu gaaugcaggc     1680

aaaucgacca cuaacaucau gaucaccacc aucaucaucg ucaucauagu cauccuccug     1740

ucccuuaucg ccgucggucu uuuauuauac ugcaaagccc gcagcacccc cgucacccuc     1800

ucuaaggacc aacucagcgg caucaauaac aucgcauucu cuaacuaagg acuaguggaa     1860

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1920

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1980

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2100

cucuuuucag agccaccaga auu                                             2123


<210>  1003
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1003
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1004
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1004
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcuccac gcccgugacc cugagcaagg accagcucuc cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1005
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1005
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1006
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1006
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggucuac acccgugacg cucagcaagg accagcuguc cgggauaaac     1800

aauaucgcuu uuucaaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1007
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1007
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1008
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1008
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccgguccac ccccgugacg cuuagcaagg accagcuguc uggaauuaac     1800

aauaucgcuu uuuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1009
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1009
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuauuaau ccucaaagcg      120

aacgcuauua cuaccauucu aacagcaguc acauucugcu ucgccucagg ccaaaacauu      180

acagaagaau uuuaccaauc aacaugcucu gccguaucaa aaggcuaccu auccgcccua      240

cgaacaggcu gguacacaag cguaauaaca aucgaacuau caaacauaaa agaaaacaaa      300

ugcaacggua cagacgccaa aguuaaacua auaaaacaag aacucgauaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa ucaacaccug caacaaacaa uagagccagg      420

agagaauuac cucgauucau gaauuacaca cucaauaacg caaaaaaaac caacguuaca      480

cuaucaaaaa aaagaaaacg acgauucuua ggauuccuac ucggagucgg aucagcaaua      540

gcaucuggcg uugcaguaug caaaguauua cacuuagaag gugaagucaa uaaaauaaaa      600

agcgcgcuac uaaguacaaa caaagcaguc gucucccuau caaacggagu cucaguccua      660

acauucaaag uacucgaccu aaaaaauuac auagauaaac aacuacuucc aauauuaaac      720

aaacaauccu guagcaucag caauauagaa acaguaauag aauuucaaca aaaaaacaac      780

cgauuauuag aaaucacucg agaauuuucc guaaacgccg ggguaacaac uccagucuca      840

accuacaugc uaaccaauuc agaacuauug agcuuaauaa acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaauguc uaacaauguu caaaucguca gacaacaaag uuacaguaua      960

auguguauaa ucaaagaaga aguccuagca uacguagucc aacucccacu auauggaguu     1020

aucgacacac cauguuggaa auuacacacc ucaccauuau gcacaaccaa uacaaaagaa     1080

ggaucaaaca uaugccuuac acggacagac cgcggauggu auugugacaa cgcuggcuca     1140

gucuccuuuu ucccacaagc agaaacaugc aaaguacaau caaacagagu cuuuugcgau     1200

accaugaacu cacuuacauu accaagcgaa guaaaucuuu guaacgucga caucuucaau     1260

ccuaaauaug acugcaaaau caugaccuca aaaacagacg uuagcucuuc aguaaucacu     1320

agcuuaggag caaucguauc augcuacggc aaaacaaaau guacagcauc aaauaaaaac     1380

agaggaauca uaaaaacauu uucaaacgga ugcgauuaug uaagcaacaa aggaguagau     1440

acuguaagcg uaggaaacac auuguacuau guaaacaaac aagaaggaaa aucacucuau     1500

guaaaaggag aaccuauaau caauuucuac gauccauuag uguucccauc agaugaauuu     1560

gacgccucaa uaucacaagu uaaugaaaaa auaaaucaau cgcuagcauu cauacguaaa     1620

ucagaugaau uacuacauaa cguaaacgca ggcaaaucca caacaaauau caugaucaca     1680

acaauuauaa uaguaauaau aguaauacua cuaucacuaa uagccguagg acuccuacua     1740

uacugcaaag caagaucuac uccaguaacc cucucaaaag aucaacuaag cggaauuaau     1800

aacaucgcau ucagcaacua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1010
<211>  2100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1010
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuuau ccucaaagcc      120

aacgccauca ccaccauccu cacagcagua accuuuugcu ucgccucagg ccaaaauauc      180

acagaagaau uuuaccagag uaccugcucc gccguaucca aaggauaccu cagcgcgcuc      240

cgcaccggcu gguacacuuc aguaaucaca aucgaacuau ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa auacaaaaau      360

gccguaacag aacuacaacu guuaaugcag agcacacccg ccaccaacaa ccgcgcccgc      420

cgggaacucc cccgauucau gaacuacaca cucaacaacg ccaaaaagac gaacgucacc      480

cucagcaaga aacgaaaacg cagauuccuc gguuuccuac uaggcguagg cucagcaaua      540

gccuccggag uagccgucug caaaguccug cacuuagaag gcgaagucaa caaaaucaaa      600

uccgcccuac ucuccacgaa caaagccguc gucucccugu ccaacggugu cuccguuuua      660

accuucaaag uucuggaccu caaaaacuac auagacaaac agcuucuccc cauccucaac      720

aaacaauccu guagcaucuc caacaucgaa accgucauag aauuucaaca gaaaaacaac      780

agacugcucg aaaucacccg cgaguucucc gucaacgccg gcgucacgac ucccgucucc      840

accuauaugc ucacgaacuc ggaacuccuu ucccuaauca acgacaugcc gaucaccaac      900

gaccaaaaga aacucauguc aaacaacgua caaauugucc gccaacaauc auacuccauc      960

augugcauaa uuaaagaaga aguccucgca uacguagucc aacucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa acuccacacc uccccacucu gcacaaccaa caccaaagaa     1080

ggcucaaaca uaugccuaac gcgcaccgau cgcgguuggu acugcgacaa cgccgguucc     1140

gucagcuucu ucccccaagc agagacaugc aaaguccaau caaaccgcgu cuucugcgac     1200

accaugaacu cacuaacccu uccaagcgaa gucaaccucu gcaacguuga caucuucaac     1260

cccaaauacg acuguaaaau caugaccucc aagaccgacg uauccucuuc cgucaucaca     1320

ucccuaggcg cuaucguauc cugcuauggu aaaaccaaau gcaccgccuc caacaaaaac     1380

cgcggcauca ucaagacauu uuccaacggc ugcgacuacg ugagcaacaa aggcgucgac     1440

accgucuccg uaggcaacac ccucuacuau guaaacaaac aagagggcaa aucacucuac     1500

gucaaagggg aacccaucau caacuucuac gacccgcucg uauuccccag cgaugaguuc     1560

gacgccucca ucucccaggu caacgaaaag auaaaccaau cacucgcauu cauucguaaa     1620

uccgacgaac uccuacacaa cgugaaugca ggcaaaucga ccacuaacau caugaucacc     1680

accaucauca ucgucaucau agucauccuc cugucccuua ucgccgucgg ucuuuuauua     1740

uacugcaaag cccgcagcac ccccgucacc cucucuaagg accaacucag cggcaucaau     1800

aacaucgcau ucucuaacua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1860

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1920

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2040

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2100


<210>  1011
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1011
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1012
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1012
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcuccac gcccgugacc cugagcaagg accagcucuc cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1013
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1013
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1014
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1014
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggucuac acccgugacg cucagcaagg accagcuguc cgggauaaac     1800

aauaucgcuu uuucaaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1015
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1015
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1016
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1016
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccgguccac ccccgugacg cuuagcaagg accagcuguc uggaauuaac     1800

aauaucgcuu uuuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1017
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1017
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuauuaau ccucaaagcg      120

aacgcuauua cuaccauucu aacagcaguc acauucugcu ucgccucagg ccaaaacauu      180

acagaagaau uuuaccaauc aacaugcucu gccguaucaa aaggcuaccu auccgcccua      240

cgaacaggcu gguacacaag cguaauaaca aucgaacuau caaacauaaa agaaaacaaa      300

ugcaacggua cagacgccaa aguuaaacua auaaaacaag aacucgauaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa ucaacaccug caacaaacaa uagagccagg      420

agagaauuac cucgauucau gaauuacaca cucaauaacg caaaaaaaac caacguuaca      480

cuaucaaaaa aaagaaaacg acgauucuua ggauuccuac ucggagucgg aucagcaaua      540

gcaucuggcg uugcaguaug caaaguauua cacuuagaag gugaagucaa uaaaauaaaa      600

agcgcgcuac uaaguacaaa caaagcaguc gucucccuau caaacggagu cucaguccua      660

acauucaaag uacucgaccu aaaaaauuac auagauaaac aacuacuucc aauauuaaac      720

aaacaauccu guagcaucag caauauagaa acaguaauag aauuucaaca aaaaaacaac      780

cgauuauuag aaaucacucg agaauuuucc guaaacgccg ggguaacaac uccagucuca      840

accuacaugc uaaccaauuc agaacuauug agcuuaauaa acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaauguc uaacaauguu caaaucguca gacaacaaag uuacaguaua      960

auguguauaa ucaaagaaga aguccuagca uacguagucc aacucccacu auauggaguu     1020

aucgacacac cauguuggaa auuacacacc ucaccauuau gcacaaccaa uacaaaagaa     1080

ggaucaaaca uaugccuuac acggacagac cgcggauggu auugugacaa cgcuggcuca     1140

gucuccuuuu ucccacaagc agaaacaugc aaaguacaau caaacagagu cuuuugcgau     1200

accaugaacu cacuuacauu accaagcgaa guaaaucuuu guaacgucga caucuucaau     1260

ccuaaauaug acugcaaaau caugaccuca aaaacagacg uuagcucuuc aguaaucacu     1320

agcuuaggag caaucguauc augcuacggc aaaacaaaau guacagcauc aaauaaaaac     1380

agaggaauca uaaaaacauu uucaaacgga ugcgauuaug uaagcaacaa aggaguagau     1440

acuguaagcg uaggaaacac auuguacuau guaaacaaac aagaaggaaa aucacucuau     1500

guaaaaggag aaccuauaau caauuucuac gauccauuag uguucccauc agaugaauuu     1560

gacgccucaa uaucacaagu uaaugaaaaa auaaaucaau cgcuagcauu cauacguaaa     1620

ucagaugaau uacuacauaa cguaaacgca ggcaaaucca caacaaauau caugaucaca     1680

acaauuauaa uaguaauaau aguaauacua cuaucacuaa uagccguagg acuccuacua     1740

uacugcaaag caagaucuac uccaguaacc cucucaaaag aucaacuaag cggaauuaau     1800

aacaucgcau ucagcaacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1018
<211>  2096
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1018
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuuau ccucaaagcc      120

aacgccauca ccaccauccu cacagcagua accuuuugcu ucgccucagg ccaaaauauc      180

acagaagaau uuuaccagag uaccugcucc gccguaucca aaggauaccu cagcgcgcuc      240

cgcaccggcu gguacacuuc aguaaucaca aucgaacuau ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa auacaaaaau      360

gccguaacag aacuacaacu guuaaugcag agcacacccg ccaccaacaa ccgcgcccgc      420

cgggaacucc cccgauucau gaacuacaca cucaacaacg ccaaaaagac gaacgucacc      480

cucagcaaga aacgaaaacg cagauuccuc gguuuccuac uaggcguagg cucagcaaua      540

gccuccggag uagccgucug caaaguccug cacuuagaag gcgaagucaa caaaaucaaa      600

uccgcccuac ucuccacgaa caaagccguc gucucccugu ccaacggugu cuccguuuua      660

accuucaaag uucuggaccu caaaaacuac auagacaaac agcuucuccc cauccucaac      720

aaacaauccu guagcaucuc caacaucgaa accgucauag aauuucaaca gaaaaacaac      780

agacugcucg aaaucacccg cgaguucucc gucaacgccg gcgucacgac ucccgucucc      840

accuauaugc ucacgaacuc ggaacuccuu ucccuaauca acgacaugcc gaucaccaac      900

gaccaaaaga aacucauguc aaacaacgua caaauugucc gccaacaauc auacuccauc      960

augugcauaa uuaaagaaga aguccucgca uacguagucc aacucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa acuccacacc uccccacucu gcacaaccaa caccaaagaa     1080

ggcucaaaca uaugccuaac gcgcaccgau cgcgguuggu acugcgacaa cgccgguucc     1140

gucagcuucu ucccccaagc agagacaugc aaaguccaau caaaccgcgu cuucugcgac     1200

accaugaacu cacuaacccu uccaagcgaa gucaaccucu gcaacguuga caucuucaac     1260

cccaaauacg acuguaaaau caugaccucc aagaccgacg uauccucuuc cgucaucaca     1320

ucccuaggcg cuaucguauc cugcuauggu aaaaccaaau gcaccgccuc caacaaaaac     1380

cgcggcauca ucaagacauu uuccaacggc ugcgacuacg ugagcaacaa aggcgucgac     1440

accgucuccg uaggcaacac ccucuacuau guaaacaaac aagagggcaa aucacucuac     1500

gucaaagggg aacccaucau caacuucuac gacccgcucg uauuccccag cgaugaguuc     1560

gacgccucca ucucccaggu caacgaaaag auaaaccaau cacucgcauu cauucguaaa     1620

uccgacgaac uccuacacaa cgugaaugca ggcaaaucga ccacuaacau caugaucacc     1680

accaucauca ucgucaucau agucauccuc cugucccuua ucgccgucgg ucuuuuauua     1740

uacugcaaag cccgcagcac ccccgucacc cucucuaagg accaacucag cggcaucaau     1800

aacaucgcau ucucuaacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1860

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1920

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     2040

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2096


<210>  1019
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1019
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1020
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1020
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu ccacgcccgu gacccugagc aaggaccagc ucuccggcau caacaacauc     1800

gccuucagca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1021
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1021
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1022
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1022
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu cuacacccgu gacgcucagc aaggaccagc uguccgggau aaacaauauc     1800

gcuuuuucaa acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1023
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1023
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1024
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1024
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu ccacccccgu gacgcuuagc aaggaccagc ugucuggaau uaacaauauc     1800

gcuuuuucca acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1025
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1025
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuau uaauccucaa agcgaacgcu      120

auuacuacca uucuaacagc agucacauuc ugcuucgccu caggccaaaa cauuacagaa      180

gaauuuuacc aaucaacaug cucugccgua ucaaaaggcu accuauccgc ccuacgaaca      240

ggcugguaca caagcguaau aacaaucgaa cuaucaaaca uaaaagaaaa caaaugcaac      300

gguacagacg ccaaaguuaa acuaauaaaa caagaacucg auaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaucaaca ccugcaacaa acaauagagc caggagagaa      420

uuaccucgau ucaugaauua cacacucaau aacgcaaaaa aaaccaacgu uacacuauca      480

aaaaaaagaa aacgacgauu cuuaggauuc cuacucggag ucggaucagc aauagcaucu      540

ggcguugcag uaugcaaagu auuacacuua gaaggugaag ucaauaaaau aaaaagcgcg      600

cuacuaagua caaacaaagc agucgucucc cuaucaaacg gagucucagu ccuaacauuc      660

aaaguacucg accuaaaaaa uuacauagau aaacaacuac uuccaauauu aaacaaacaa      720

uccuguagca ucagcaauau agaaacagua auagaauuuc aacaaaaaaa caaccgauua      780

uuagaaauca cucgagaauu uuccguaaac gccgggguaa caacuccagu cucaaccuac      840

augcuaacca auucagaacu auugagcuua auaaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugucuaacaa uguucaaauc gucagacaac aaaguuacag uauaaugugu      960

auaaucaaag aagaaguccu agcauacgua guccaacucc cacuauaugg aguuaucgac     1020

acaccauguu ggaaauuaca caccucacca uuaugcacaa ccaauacaaa agaaggauca     1080

aacauaugcc uuacacggac agaccgcgga ugguauugug acaacgcugg cucagucucc     1140

uuuuucccac aagcagaaac augcaaagua caaucaaaca gagucuuuug cgauaccaug     1200

aacucacuua cauuaccaag cgaaguaaau cuuuguaacg ucgacaucuu caauccuaaa     1260

uaugacugca aaaucaugac cucaaaaaca gacguuagcu cuucaguaau cacuagcuua     1320

ggagcaaucg uaucaugcua cggcaaaaca aaauguacag caucaaauaa aaacagagga     1380

aucauaaaaa cauuuucaaa cggaugcgau uauguaagca acaaaggagu agauacugua     1440

agcguaggaa acacauugua cuauguaaac aaacaagaag gaaaaucacu cuauguaaaa     1500

ggagaaccua uaaucaauuu cuacgaucca uuaguguucc caucagauga auuugacgcc     1560

ucaauaucac aaguuaauga aaaaauaaau caaucgcuag cauucauacg uaaaucagau     1620

gaauuacuac auaacguaaa cgcaggcaaa uccacaacaa auaucaugau cacaacaauu     1680

auaauaguaa uaauaguaau acuacuauca cuaauagccg uaggacuccu acuauacugc     1740

aaagcaagau cuacuccagu aacccucuca aaagaucaac uaagcggaau uaauaacauc     1800

gcauucagca acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1026
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1026
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uuauccucaa agccaacgcc      120

aucaccacca uccucacagc aguaaccuuu ugcuucgccu caggccaaaa uaucacagaa      180

gaauuuuacc agaguaccug cuccgccgua uccaaaggau accucagcgc gcuccgcacc      240

ggcugguaca cuucaguaau cacaaucgaa cuauccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg cgaaagucaa acucaucaaa caagaacuag acaaauacaa aaaugccgua      360

acagaacuac aacuguuaau gcagagcaca cccgccacca acaaccgcgc ccgccgggaa      420

cucccccgau ucaugaacua cacacucaac aacgccaaaa agacgaacgu cacccucagc      480

aagaaacgaa aacgcagauu ccucgguuuc cuacuaggcg uaggcucagc aauagccucc      540

ggaguagccg ucugcaaagu ccugcacuua gaaggcgaag ucaacaaaau caaauccgcc      600

cuacucucca cgaacaaagc cgucgucucc cuguccaacg gugucuccgu uuuaaccuuc      660

aaaguucugg accucaaaaa cuacauagac aaacagcuuc uccccauccu caacaaacaa      720

uccuguagca ucuccaacau cgaaaccguc auagaauuuc aacagaaaaa caacagacug      780

cucgaaauca cccgcgaguu cuccgucaac gccggcguca cgacucccgu cuccaccuau      840

augcucacga acucggaacu ccuuucccua aucaacgaca ugccgaucac caacgaccaa      900

aagaaacuca ugucaaacaa cguacaaauu guccgccaac aaucauacuc caucaugugc      960

auaauuaaag aagaaguccu cgcauacgua guccaacucc cccucuacgg cgucaucgac     1020

acccccugcu ggaaacucca caccucccca cucugcacaa ccaacaccaa agaaggcuca     1080

aacauaugcc uaacgcgcac cgaucgcggu ugguacugcg acaacgccgg uuccgucagc     1140

uucuuccccc aagcagagac augcaaaguc caaucaaacc gcgucuucug cgacaccaug     1200

aacucacuaa cccuuccaag cgaagucaac cucugcaacg uugacaucuu caaccccaaa     1260

uacgacugua aaaucaugac cuccaagacc gacguauccu cuuccgucau cacaucccua     1320

ggcgcuaucg uauccugcua ugguaaaacc aaaugcaccg ccuccaacaa aaaccgcggc     1380

aucaucaaga cauuuuccaa cggcugcgac uacgugagca acaaaggcgu cgacaccguc     1440

uccguaggca acacccucua cuauguaaac aaacaagagg gcaaaucacu cuacgucaaa     1500

ggggaaccca ucaucaacuu cuacgacccg cucguauucc ccagcgauga guucgacgcc     1560

uccaucuccc aggucaacga aaagauaaac caaucacucg cauucauucg uaaauccgac     1620

gaacuccuac acaacgugaa ugcaggcaaa ucgaccacua acaucaugau caccaccauc     1680

aucaucguca ucauagucau ccuccugucc cuuaucgccg ucggucuuuu auuauacugc     1740

aaagcccgca gcacccccgu cacccucucu aaggaccaac ucagcggcau caauaacauc     1800

gcauucucua acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1860

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1027
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1027
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1028
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1028
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcuc cacgcccgug acccugagca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1029
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1029
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1030
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1030
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccagguc uacacccgug acgcucagca aggaccagcu guccgggaua     1800

aacaauaucg cuuuuucaaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1031
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1031
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1032
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1032
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccgguc cacccccgug acgcuuagca aggaccagcu gucuggaauu     1800

aacaauaucg cuuuuuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1033
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1033
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuauu aauccucaaa      120

gcgaacgcua uuacuaccau ucuaacagca gucacauucu gcuucgccuc aggccaaaac      180

auuacagaag aauuuuacca aucaacaugc ucugccguau caaaaggcua ccuauccgcc      240

cuacgaacag gcugguacac aagcguaaua acaaucgaac uaucaaacau aaaagaaaac      300

aaaugcaacg guacagacgc caaaguuaaa cuaauaaaac aagaacucga uaaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaucaacac cugcaacaaa caauagagcc      420

aggagagaau uaccucgauu caugaauuac acacucaaua acgcaaaaaa aaccaacguu      480

acacuaucaa aaaaaagaaa acgacgauuc uuaggauucc uacucggagu cggaucagca      540

auagcaucug gcguugcagu augcaaagua uuacacuuag aaggugaagu caauaaaaua      600

aaaagcgcgc uacuaaguac aaacaaagca gucgucuccc uaucaaacgg agucucaguc      660

cuaacauuca aaguacucga ccuaaaaaau uacauagaua aacaacuacu uccaauauua      720

aacaaacaau ccuguagcau cagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      780

aaccgauuau uagaaaucac ucgagaauuu uccguaaacg ccgggguaac aacuccaguc      840

ucaaccuaca ugcuaaccaa uucagaacua uugagcuuaa uaaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gucuaacaau guucaaaucg ucagacaaca aaguuacagu      960

auaaugugua uaaucaaaga agaaguccua gcauacguag uccaacuccc acuauaugga     1020

guuaucgaca caccauguug gaaauuacac accucaccau uaugcacaac caauacaaaa     1080

gaaggaucaa acauaugccu uacacggaca gaccgcggau gguauuguga caacgcuggc     1140

ucagucuccu uuuucccaca agcagaaaca ugcaaaguac aaucaaacag agucuuuugc     1200

gauaccauga acucacuuac auuaccaagc gaaguaaauc uuuguaacgu cgacaucuuc     1260

aauccuaaau augacugcaa aaucaugacc ucaaaaacag acguuagcuc uucaguaauc     1320

acuagcuuag gagcaaucgu aucaugcuac ggcaaaacaa aauguacagc aucaaauaaa     1380

aacagaggaa ucauaaaaac auuuucaaac ggaugcgauu auguaagcaa caaaggagua     1440

gauacuguaa gcguaggaaa cacauuguac uauguaaaca aacaagaagg aaaaucacuc     1500

uauguaaaag gagaaccuau aaucaauuuc uacgauccau uaguguuccc aucagaugaa     1560

uuugacgccu caauaucaca aguuaaugaa aaaauaaauc aaucgcuagc auucauacgu     1620

aaaucagaug aauuacuaca uaacguaaac gcaggcaaau ccacaacaaa uaucaugauc     1680

acaacaauua uaauaguaau aauaguaaua cuacuaucac uaauagccgu aggacuccua     1740

cuauacugca aagcaagauc uacuccagua acccucucaa aagaucaacu aagcggaauu     1800

aauaacaucg cauucagcaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1034
<211>  2023
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1034
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu uauccucaaa      120

gccaacgcca ucaccaccau ccucacagca guaaccuuuu gcuucgccuc aggccaaaau      180

aucacagaag aauuuuacca gaguaccugc uccgccguau ccaaaggaua ccucagcgcg      240

cuccgcaccg gcugguacac uucaguaauc acaaucgaac uauccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aaugccguaa cagaacuaca acuguuaaug cagagcacac ccgccaccaa caaccgcgcc      420

cgccgggaac ucccccgauu caugaacuac acacucaaca acgccaaaaa gacgaacguc      480

acccucagca agaaacgaaa acgcagauuc cucgguuucc uacuaggcgu aggcucagca      540

auagccuccg gaguagccgu cugcaaaguc cugcacuuag aaggcgaagu caacaaaauc      600

aaauccgccc uacucuccac gaacaaagcc gucgucuccc uguccaacgg ugucuccguu      660

uuaaccuuca aaguucugga ccucaaaaac uacauagaca aacagcuucu ccccauccuc      720

aacaaacaau ccuguagcau cuccaacauc gaaaccguca uagaauuuca acagaaaaac      780

aacagacugc ucgaaaucac ccgcgaguuc uccgucaacg ccggcgucac gacucccguc      840

uccaccuaua ugcucacgaa cucggaacuc cuuucccuaa ucaacgacau gccgaucacc      900

aacgaccaaa agaaacucau gucaaacaac guacaaauug uccgccaaca aucauacucc      960

aucaugugca uaauuaaaga agaaguccuc gcauacguag uccaacuccc ccucuacggc     1020

gucaucgaca cccccugcug gaaacuccac accuccccac ucugcacaac caacaccaaa     1080

gaaggcucaa acauaugccu aacgcgcacc gaucgcgguu gguacugcga caacgccggu     1140

uccgucagcu ucuuccccca agcagagaca ugcaaagucc aaucaaaccg cgucuucugc     1200

gacaccauga acucacuaac ccuuccaagc gaagucaacc ucugcaacgu ugacaucuuc     1260

aaccccaaau acgacuguaa aaucaugacc uccaagaccg acguauccuc uuccgucauc     1320

acaucccuag gcgcuaucgu auccugcuau gguaaaacca aaugcaccgc cuccaacaaa     1380

aaccgcggca ucaucaagac auuuuccaac ggcugcgacu acgugagcaa caaaggcguc     1440

gacaccgucu ccguaggcaa cacccucuac uauguaaaca aacaagaggg caaaucacuc     1500

uacgucaaag gggaacccau caucaacuuc uacgacccgc ucguauuccc cagcgaugag     1560

uucgacgccu ccaucuccca ggucaacgaa aagauaaacc aaucacucgc auucauucgu     1620

aaauccgacg aacuccuaca caacgugaau gcaggcaaau cgaccacuaa caucaugauc     1680

accaccauca ucaucgucau cauagucauc cuccuguccc uuaucgccgu cggucuuuua     1740

uuauacugca aagcccgcag cacccccguc acccucucua aggaccaacu cagcggcauc     1800

aauaacaucg cauucucuaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1860

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1980

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2023


<210>  1035
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1035
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1036
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1036
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu ccacgcccgu gacccugagc aaggaccagc ucuccggcau caacaacauc     1800

gccuucagca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1037
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1037
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1038
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1038
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu cuacacccgu gacgcucagc aaggaccagc uguccgggau aaacaauauc     1800

gcuuuuucaa acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1039
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1039
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1040
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1040
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu ccacccccgu gacgcuuagc aaggaccagc ugucuggaau uaacaauauc     1800

gcuuuuucca acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1041
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1041
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuau uaauccucaa agcgaacgcu      120

auuacuacca uucuaacagc agucacauuc ugcuucgccu caggccaaaa cauuacagaa      180

gaauuuuacc aaucaacaug cucugccgua ucaaaaggcu accuauccgc ccuacgaaca      240

ggcugguaca caagcguaau aacaaucgaa cuaucaaaca uaaaagaaaa caaaugcaac      300

gguacagacg ccaaaguuaa acuaauaaaa caagaacucg auaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaucaaca ccugcaacaa acaauagagc caggagagaa      420

uuaccucgau ucaugaauua cacacucaau aacgcaaaaa aaaccaacgu uacacuauca      480

aaaaaaagaa aacgacgauu cuuaggauuc cuacucggag ucggaucagc aauagcaucu      540

ggcguugcag uaugcaaagu auuacacuua gaaggugaag ucaauaaaau aaaaagcgcg      600

cuacuaagua caaacaaagc agucgucucc cuaucaaacg gagucucagu ccuaacauuc      660

aaaguacucg accuaaaaaa uuacauagau aaacaacuac uuccaauauu aaacaaacaa      720

uccuguagca ucagcaauau agaaacagua auagaauuuc aacaaaaaaa caaccgauua      780

uuagaaauca cucgagaauu uuccguaaac gccgggguaa caacuccagu cucaaccuac      840

augcuaacca auucagaacu auugagcuua auaaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugucuaacaa uguucaaauc gucagacaac aaaguuacag uauaaugugu      960

auaaucaaag aagaaguccu agcauacgua guccaacucc cacuauaugg aguuaucgac     1020

acaccauguu ggaaauuaca caccucacca uuaugcacaa ccaauacaaa agaaggauca     1080

aacauaugcc uuacacggac agaccgcgga ugguauugug acaacgcugg cucagucucc     1140

uuuuucccac aagcagaaac augcaaagua caaucaaaca gagucuuuug cgauaccaug     1200

aacucacuua cauuaccaag cgaaguaaau cuuuguaacg ucgacaucuu caauccuaaa     1260

uaugacugca aaaucaugac cucaaaaaca gacguuagcu cuucaguaau cacuagcuua     1320

ggagcaaucg uaucaugcua cggcaaaaca aaauguacag caucaaauaa aaacagagga     1380

aucauaaaaa cauuuucaaa cggaugcgau uauguaagca acaaaggagu agauacugua     1440

agcguaggaa acacauugua cuauguaaac aaacaagaag gaaaaucacu cuauguaaaa     1500

ggagaaccua uaaucaauuu cuacgaucca uuaguguucc caucagauga auuugacgcc     1560

ucaauaucac aaguuaauga aaaaauaaau caaucgcuag cauucauacg uaaaucagau     1620

gaauuacuac auaacguaaa cgcaggcaaa uccacaacaa auaucaugau cacaacaauu     1680

auaauaguaa uaauaguaau acuacuauca cuaauagccg uaggacuccu acuauacugc     1740

aaagcaagau cuacuccagu aacccucuca aaagaucaac uaagcggaau uaauaacauc     1800

gcauucagca acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1042
<211>  2078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1042
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uuauccucaa agccaacgcc      120

aucaccacca uccucacagc aguaaccuuu ugcuucgccu caggccaaaa uaucacagaa      180

gaauuuuacc agaguaccug cuccgccgua uccaaaggau accucagcgc gcuccgcacc      240

ggcugguaca cuucaguaau cacaaucgaa cuauccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg cgaaagucaa acucaucaaa caagaacuag acaaauacaa aaaugccgua      360

acagaacuac aacuguuaau gcagagcaca cccgccacca acaaccgcgc ccgccgggaa      420

cucccccgau ucaugaacua cacacucaac aacgccaaaa agacgaacgu cacccucagc      480

aagaaacgaa aacgcagauu ccucgguuuc cuacuaggcg uaggcucagc aauagccucc      540

ggaguagccg ucugcaaagu ccugcacuua gaaggcgaag ucaacaaaau caaauccgcc      600

cuacucucca cgaacaaagc cgucgucucc cuguccaacg gugucuccgu uuuaaccuuc      660

aaaguucugg accucaaaaa cuacauagac aaacagcuuc uccccauccu caacaaacaa      720

uccuguagca ucuccaacau cgaaaccguc auagaauuuc aacagaaaaa caacagacug      780

cucgaaauca cccgcgaguu cuccgucaac gccggcguca cgacucccgu cuccaccuau      840

augcucacga acucggaacu ccuuucccua aucaacgaca ugccgaucac caacgaccaa      900

aagaaacuca ugucaaacaa cguacaaauu guccgccaac aaucauacuc caucaugugc      960

auaauuaaag aagaaguccu cgcauacgua guccaacucc cccucuacgg cgucaucgac     1020

acccccugcu ggaaacucca caccucccca cucugcacaa ccaacaccaa agaaggcuca     1080

aacauaugcc uaacgcgcac cgaucgcggu ugguacugcg acaacgccgg uuccgucagc     1140

uucuuccccc aagcagagac augcaaaguc caaucaaacc gcgucuucug cgacaccaug     1200

aacucacuaa cccuuccaag cgaagucaac cucugcaacg uugacaucuu caaccccaaa     1260

uacgacugua aaaucaugac cuccaagacc gacguauccu cuuccgucau cacaucccua     1320

ggcgcuaucg uauccugcua ugguaaaacc aaaugcaccg ccuccaacaa aaaccgcggc     1380

aucaucaaga cauuuuccaa cggcugcgac uacgugagca acaaaggcgu cgacaccguc     1440

uccguaggca acacccucua cuauguaaac aaacaagagg gcaaaucacu cuacgucaaa     1500

ggggaaccca ucaucaacuu cuacgacccg cucguauucc ccagcgauga guucgacgcc     1560

uccaucuccc aggucaacga aaagauaaac caaucacucg cauucauucg uaaauccgac     1620

gaacuccuac acaacgugaa ugcaggcaaa ucgaccacua acaucaugau caccaccauc     1680

aucaucguca ucauagucau ccuccugucc cuuaucgccg ucggucuuuu auuauacugc     1740

aaagcccgca gcacccccgu cacccucucu aaggaccaac ucagcggcau caauaacauc     1800

gcauucucua acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1860

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1920

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     2040

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2078


<210>  1043
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1043
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1044
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1044
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcuccacgc ccgugacccu gagcaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc agcaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1045
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1045
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1046
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1046
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggucuacac ccgugacgcu cagcaaggac     1860

cagcuguccg ggauaaacaa uaucgcuuuu ucaaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1047
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1047
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1048
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1048
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cgguccaccc ccgugacgcu uagcaaggac     1860

cagcugucug gaauuaacaa uaucgcuuuu uccaacugag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1049
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1049
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuauuaaucc ucaaagcgaa cgcuauuacu accauucuaa cagcagucac auucugcuuc      240

gccucaggcc aaaacauuac agaagaauuu uaccaaucaa caugcucugc cguaucaaaa      300

ggcuaccuau ccgcccuacg aacaggcugg uacacaagcg uaauaacaau cgaacuauca      360

aacauaaaag aaaacaaaug caacgguaca gacgccaaag uuaaacuaau aaaacaagaa      420

cucgauaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaauc aacaccugca      480

acaaacaaua gagccaggag agaauuaccu cgauucauga auuacacacu caauaacgca      540

aaaaaaacca acguuacacu aucaaaaaaa agaaaacgac gauucuuagg auuccuacuc      600

ggagucggau cagcaauagc aucuggcguu gcaguaugca aaguauuaca cuuagaaggu      660

gaagucaaua aaauaaaaag cgcgcuacua aguacaaaca aagcagucgu cucccuauca      720

aacggagucu caguccuaac auucaaagua cucgaccuaa aaaauuacau agauaaacaa      780

cuacuuccaa uauuaaacaa acaauccugu agcaucagca auauagaaac aguaauagaa      840

uuucaacaaa aaaacaaccg auuauuagaa aucacucgag aauuuuccgu aaacgccggg      900

guaacaacuc cagucucaac cuacaugcua accaauucag aacuauugag cuuaauaaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugucua acaauguuca aaucgucaga     1020

caacaaaguu acaguauaau guguauaauc aaagaagaag uccuagcaua cguaguccaa     1080

cucccacuau auggaguuau cgacacacca uguuggaaau uacacaccuc accauuaugc     1140

acaaccaaua caaaagaagg aucaaacaua ugccuuacac ggacagaccg cggaugguau     1200

ugugacaacg cuggcucagu cuccuuuuuc ccacaagcag aaacaugcaa aguacaauca     1260

aacagagucu uuugcgauac caugaacuca cuuacauuac caagcgaagu aaaucuuugu     1320

aacgucgaca ucuucaaucc uaaauaugac ugcaaaauca ugaccucaaa aacagacguu     1380

agcucuucag uaaucacuag cuuaggagca aucguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa auaaaaacag aggaaucaua aaaacauuuu caaacggaug cgauuaugua     1500

agcaacaaag gaguagauac uguaagcgua ggaaacacau uguacuaugu aaacaaacaa     1560

gaaggaaaau cacucuaugu aaaaggagaa ccuauaauca auuucuacga uccauuagug     1620

uucccaucag augaauuuga cgccucaaua ucacaaguua augaaaaaau aaaucaaucg     1680

cuagcauuca uacguaaauc agaugaauua cuacauaacg uaaacgcagg caaauccaca     1740

acaaauauca ugaucacaac aauuauaaua guaauaauag uaauacuacu aucacuaaua     1800

gccguaggac uccuacuaua cugcaaagca agaucuacuc caguaacccu cucaaaagau     1860

caacuaagcg gaauuaauaa caucgcauuc agcaacuaag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1050
<211>  2394
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1050
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuuaucc ucaaagccaa cgccaucacc accauccuca cagcaguaac cuuuugcuuc      240

gccucaggcc aaaauaucac agaagaauuu uaccagagua ccugcuccgc cguauccaaa      300

ggauaccuca gcgcgcuccg caccggcugg uacacuucag uaaucacaau cgaacuaucc      360

aacaucaaag aaaacaaaug caacggcacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaaugc cguaacagaa cuacaacugu uaaugcagag cacacccgcc      480

accaacaacc gcgcccgccg ggaacucccc cgauucauga acuacacacu caacaacgcc      540

aaaaagacga acgucacccu cagcaagaaa cgaaaacgca gauuccucgg uuuccuacua      600

ggcguaggcu cagcaauagc cuccggagua gccgucugca aaguccugca cuuagaaggc      660

gaagucaaca aaaucaaauc cgcccuacuc uccacgaaca aagccgucgu cucccugucc      720

aacggugucu ccguuuuaac cuucaaaguu cuggaccuca aaaacuacau agacaaacag      780

cuucucccca uccucaacaa acaauccugu agcaucucca acaucgaaac cgucauagaa      840

uuucaacaga aaaacaacag acugcucgaa aucacccgcg aguucuccgu caacgccggc      900

gucacgacuc ccgucuccac cuauaugcuc acgaacucgg aacuccuuuc ccuaaucaac      960

gacaugccga ucaccaacga ccaaaagaaa cucaugucaa acaacguaca aauuguccgc     1020

caacaaucau acuccaucau gugcauaauu aaagaagaag uccucgcaua cguaguccaa     1080

cucccccucu acggcgucau cgacaccccc ugcuggaaac uccacaccuc cccacucugc     1140

acaaccaaca ccaaagaagg cucaaacaua ugccuaacgc gcaccgaucg cgguugguac     1200

ugcgacaacg ccgguuccgu cagcuucuuc ccccaagcag agacaugcaa aguccaauca     1260

aaccgcgucu ucugcgacac caugaacuca cuaacccuuc caagcgaagu caaccucugc     1320

aacguugaca ucuucaaccc caaauacgac uguaaaauca ugaccuccaa gaccgacgua     1380

uccucuuccg ucaucacauc ccuaggcgcu aucguauccu gcuaugguaa aaccaaaugc     1440

accgccucca acaaaaaccg cggcaucauc aagacauuuu ccaacggcug cgacuacgug     1500

agcaacaaag gcgucgacac cgucuccgua ggcaacaccc ucuacuaugu aaacaaacaa     1560

gagggcaaau cacucuacgu caaaggggaa cccaucauca acuucuacga cccgcucgua     1620

uuccccagcg augaguucga cgccuccauc ucccagguca acgaaaagau aaaccaauca     1680

cucgcauuca uucguaaauc cgacgaacuc cuacacaacg ugaaugcagg caaaucgacc     1740

acuaacauca ugaucaccac caucaucauc gucaucauag ucauccuccu gucccuuauc     1800

gccgucgguc uuuuauuaua cugcaaagcc cgcagcaccc ccgucacccu cucuaaggac     1860

caacucagcg gcaucaauaa caucgcauuc ucuaacuaag gacuagugaa gggaacaccc     1920

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1980

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     2040

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     2100

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     2160

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2220

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2340

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2394


<210>  1051
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1051
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1052
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1052
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcucca     1740

cgcccgugac ccugagcaag gaccagcucu ccggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1053
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1053
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1054
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1054
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggucua     1740

cacccgugac gcucagcaag gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1055
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1055
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1056
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1056
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggucca     1740

cccccgugac gcuuagcaag gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu     1800

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1057
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1057
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc      120

uaacagcagu cacauucugc uucgccucag gccaaaacau uacagaagaa uuuuaccaau      180

caacaugcuc ugccguauca aaaggcuacc uauccgcccu acgaacaggc ugguacacaa      240

gcguaauaac aaucgaacua ucaaacauaa aagaaaacaa augcaacggu acagacgcca      300

aaguuaaacu aauaaaacaa gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aucaacaccu gcaacaaaca auagagccag gagagaauua ccucgauuca      420

ugaauuacac acucaauaac gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac      480

gacgauucuu aggauuccua cucggagucg gaucagcaau agcaucuggc guugcaguau      540

gcaaaguauu acacuuagaa ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa      600

acaaagcagu cgucucccua ucaaacggag ucucaguccu aacauucaaa guacucgacc      660

uaaaaaauua cauagauaaa caacuacuuc caauauuaaa caaacaaucc uguagcauca      720

gcaauauaga aacaguaaua gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc      780

gagaauuuuc cguaaacgcc gggguaacaa cuccagucuc aaccuacaug cuaaccaauu      840

cagaacuauu gagcuuaaua aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu      900

cuaacaaugu ucaaaucguc agacaacaaa guuacaguau aauguguaua aucaaagaag      960

aaguccuagc auacguaguc caacucccac uauauggagu uaucgacaca ccauguugga     1020

aauuacacac cucaccauua ugcacaacca auacaaaaga aggaucaaac auaugccuua     1080

cacggacaga ccgcggaugg uauugugaca acgcuggcuc agucuccuuu uucccacaag     1140

cagaaacaug caaaguacaa ucaaacagag ucuuuugcga uaccaugaac ucacuuacau     1200

uaccaagcga aguaaaucuu uguaacgucg acaucuucaa uccuaaauau gacugcaaaa     1260

ucaugaccuc aaaaacagac guuagcucuu caguaaucac uagcuuagga gcaaucguau     1320

caugcuacgg caaaacaaaa uguacagcau caaauaaaaa cagaggaauc auaaaaacau     1380

uuucaaacgg augcgauuau guaagcaaca aaggaguaga uacuguaagc guaggaaaca     1440

cauuguacua uguaaacaaa caagaaggaa aaucacucua uguaaaagga gaaccuauaa     1500

ucaauuucua cgauccauua guguucccau cagaugaauu ugacgccuca auaucacaag     1560

uuaaugaaaa aauaaaucaa ucgcuagcau ucauacguaa aucagaugaa uuacuacaua     1620

acguaaacgc aggcaaaucc acaacaaaua ucaugaucac aacaauuaua auaguaauaa     1680

uaguaauacu acuaucacua auagccguag gacuccuacu auacugcaaa gcaagaucua     1740

cuccaguaac ccucucaaaa gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu     1800

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1058
<211>  2077
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1058
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuua uccucaaagc caacgccauc accaccaucc      120

ucacagcagu aaccuuuugc uucgccucag gccaaaauau cacagaagaa uuuuaccaga      180

guaccugcuc cgccguaucc aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu      240

caguaaucac aaucgaacua uccaacauca aagaaaacaa augcaacggc accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa ugccguaaca gaacuacaac      360

uguuaaugca gagcacaccc gccaccaaca accgcgcccg ccgggaacuc ccccgauuca      420

ugaacuacac acucaacaac gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac      480

gcagauuccu cgguuuccua cuaggcguag gcucagcaau agccuccgga guagccgucu      540

gcaaaguccu gcacuuagaa ggcgaaguca acaaaaucaa auccgcccua cucuccacga      600

acaaagccgu cgucucccug uccaacggug ucuccguuuu aaccuucaaa guucuggacc      660

ucaaaaacua cauagacaaa cagcuucucc ccauccucaa caaacaaucc uguagcaucu      720

ccaacaucga aaccgucaua gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacga cucccgucuc caccuauaug cucacgaacu      840

cggaacuccu uucccuaauc aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu      900

caaacaacgu acaaauuguc cgccaacaau cauacuccau caugugcaua auuaaagaag      960

aaguccucgc auacguaguc caacuccccc ucuacggcgu caucgacacc cccugcugga     1020

aacuccacac cuccccacuc ugcacaacca acaccaaaga aggcucaaac auaugccuaa     1080

cgcgcaccga ucgcgguugg uacugcgaca acgccgguuc cgucagcuuc uucccccaag     1140

cagagacaug caaaguccaa ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc     1200

uuccaagcga agucaaccuc ugcaacguug acaucuucaa ccccaaauac gacuguaaaa     1260

ucaugaccuc caagaccgac guauccucuu ccgucaucac aucccuaggc gcuaucguau     1320

ccugcuaugg uaaaaccaaa ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau     1380

uuuccaacgg cugcgacuac gugagcaaca aaggcgucga caccgucucc guaggcaaca     1440

cccucuacua uguaaacaaa caagagggca aaucacucua cgucaaaggg gaacccauca     1500

ucaacuucua cgacccgcuc guauucccca gcgaugaguu cgacgccucc aucucccagg     1560

ucaacgaaaa gauaaaccaa ucacucgcau ucauucguaa auccgacgaa cuccuacaca     1620

acgugaaugc aggcaaaucg accacuaaca ucaugaucac caccaucauc aucgucauca     1680

uagucauccu ccugucccuu aucgccgucg gucuuuuauu auacugcaaa gcccgcagca     1740

cccccgucac ccucucuaag gaccaacuca gcggcaucaa uaacaucgca uucucuaacu     1800

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1860

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1920

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2040

ccccccccca aaggcucuuu ucagagccac cagaauu                              2077


<210>  1059
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1059
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1060
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1060
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcuccacgc ccgugacccu gagcaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc agcaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1061
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1061
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1062
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1062
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggucuacac ccgugacgcu cagcaaggac     1860

cagcuguccg ggauaaacaa uaucgcuuuu ucaaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1063
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1063
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1064
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1064
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cgguccaccc ccgugacgcu uagcaaggac     1860

cagcugucug gaauuaacaa uaucgcuuuu uccaacugag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1065
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1065
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuauuaaucc ucaaagcgaa cgcuauuacu accauucuaa cagcagucac auucugcuuc      240

gccucaggcc aaaacauuac agaagaauuu uaccaaucaa caugcucugc cguaucaaaa      300

ggcuaccuau ccgcccuacg aacaggcugg uacacaagcg uaauaacaau cgaacuauca      360

aacauaaaag aaaacaaaug caacgguaca gacgccaaag uuaaacuaau aaaacaagaa      420

cucgauaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaauc aacaccugca      480

acaaacaaua gagccaggag agaauuaccu cgauucauga auuacacacu caauaacgca      540

aaaaaaacca acguuacacu aucaaaaaaa agaaaacgac gauucuuagg auuccuacuc      600

ggagucggau cagcaauagc aucuggcguu gcaguaugca aaguauuaca cuuagaaggu      660

gaagucaaua aaauaaaaag cgcgcuacua aguacaaaca aagcagucgu cucccuauca      720

aacggagucu caguccuaac auucaaagua cucgaccuaa aaaauuacau agauaaacaa      780

cuacuuccaa uauuaaacaa acaauccugu agcaucagca auauagaaac aguaauagaa      840

uuucaacaaa aaaacaaccg auuauuagaa aucacucgag aauuuuccgu aaacgccggg      900

guaacaacuc cagucucaac cuacaugcua accaauucag aacuauugag cuuaauaaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugucua acaauguuca aaucgucaga     1020

caacaaaguu acaguauaau guguauaauc aaagaagaag uccuagcaua cguaguccaa     1080

cucccacuau auggaguuau cgacacacca uguuggaaau uacacaccuc accauuaugc     1140

acaaccaaua caaaagaagg aucaaacaua ugccuuacac ggacagaccg cggaugguau     1200

ugugacaacg cuggcucagu cuccuuuuuc ccacaagcag aaacaugcaa aguacaauca     1260

aacagagucu uuugcgauac caugaacuca cuuacauuac caagcgaagu aaaucuuugu     1320

aacgucgaca ucuucaaucc uaaauaugac ugcaaaauca ugaccucaaa aacagacguu     1380

agcucuucag uaaucacuag cuuaggagca aucguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa auaaaaacag aggaaucaua aaaacauuuu caaacggaug cgauuaugua     1500

agcaacaaag gaguagauac uguaagcgua ggaaacacau uguacuaugu aaacaaacaa     1560

gaaggaaaau cacucuaugu aaaaggagaa ccuauaauca auuucuacga uccauuagug     1620

uucccaucag augaauuuga cgccucaaua ucacaaguua augaaaaaau aaaucaaucg     1680

cuagcauuca uacguaaauc agaugaauua cuacauaacg uaaacgcagg caaauccaca     1740

acaaauauca ugaucacaac aauuauaaua guaauaauag uaauacuacu aucacuaaua     1800

gccguaggac uccuacuaua cugcaaagca agaucuacuc caguaacccu cucaaaagau     1860

caacuaagcg gaauuaauaa caucgcauuc agcaacuaag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1066
<211>  2174
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1066
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuuaucc ucaaagccaa cgccaucacc accauccuca cagcaguaac cuuuugcuuc      240

gccucaggcc aaaauaucac agaagaauuu uaccagagua ccugcuccgc cguauccaaa      300

ggauaccuca gcgcgcuccg caccggcugg uacacuucag uaaucacaau cgaacuaucc      360

aacaucaaag aaaacaaaug caacggcacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaaugc cguaacagaa cuacaacugu uaaugcagag cacacccgcc      480

accaacaacc gcgcccgccg ggaacucccc cgauucauga acuacacacu caacaacgcc      540

aaaaagacga acgucacccu cagcaagaaa cgaaaacgca gauuccucgg uuuccuacua      600

ggcguaggcu cagcaauagc cuccggagua gccgucugca aaguccugca cuuagaaggc      660

gaagucaaca aaaucaaauc cgcccuacuc uccacgaaca aagccgucgu cucccugucc      720

aacggugucu ccguuuuaac cuucaaaguu cuggaccuca aaaacuacau agacaaacag      780

cuucucccca uccucaacaa acaauccugu agcaucucca acaucgaaac cgucauagaa      840

uuucaacaga aaaacaacag acugcucgaa aucacccgcg aguucuccgu caacgccggc      900

gucacgacuc ccgucuccac cuauaugcuc acgaacucgg aacuccuuuc ccuaaucaac      960

gacaugccga ucaccaacga ccaaaagaaa cucaugucaa acaacguaca aauuguccgc     1020

caacaaucau acuccaucau gugcauaauu aaagaagaag uccucgcaua cguaguccaa     1080

cucccccucu acggcgucau cgacaccccc ugcuggaaac uccacaccuc cccacucugc     1140

acaaccaaca ccaaagaagg cucaaacaua ugccuaacgc gcaccgaucg cgguugguac     1200

ugcgacaacg ccgguuccgu cagcuucuuc ccccaagcag agacaugcaa aguccaauca     1260

aaccgcgucu ucugcgacac caugaacuca cuaacccuuc caagcgaagu caaccucugc     1320

aacguugaca ucuucaaccc caaauacgac uguaaaauca ugaccuccaa gaccgacgua     1380

uccucuuccg ucaucacauc ccuaggcgcu aucguauccu gcuaugguaa aaccaaaugc     1440

accgccucca acaaaaaccg cggcaucauc aagacauuuu ccaacggcug cgacuacgug     1500

agcaacaaag gcgucgacac cgucuccgua ggcaacaccc ucuacuaugu aaacaaacaa     1560

gagggcaaau cacucuacgu caaaggggaa cccaucauca acuucuacga cccgcucgua     1620

uuccccagcg augaguucga cgccuccauc ucccagguca acgaaaagau aaaccaauca     1680

cucgcauuca uucguaaauc cgacgaacuc cuacacaacg ugaaugcagg caaaucgacc     1740

acuaacauca ugaucaccac caucaucauc gucaucauag ucauccuccu gucccuuauc     1800

gccgucgguc uuuuauuaua cugcaaagcc cgcagcaccc ccgucacccu cucuaaggac     1860

caacucagcg gcaucaauaa caucgcauuc ucuaacuaag gacuagugga agcauuuucc     1920

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1980

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     2040

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2160

gagccaccag aauu                                                       2174


<210>  1067
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1067
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      540

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      600

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      660

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      780

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      840

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      900

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      960

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc     1020

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1080

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1140

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1200

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1380

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1500

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1560

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1680

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1740

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1800

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1068
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1068
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      540

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      600

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      660

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      780

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      840

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      960

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug     1020

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1080

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1140

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1200

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1320

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1380

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1500

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1560

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1620

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1680

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1740

aucgccgucg ggcugcuccu guacugcaag gcgcgcucca cgcccgugac ccugagcaag     1800

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1069
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1069
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      480

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      540

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      600

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      660

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      720

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      780

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      840

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      960

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc     1020

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1080

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1140

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1200

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1380

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1440

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1500

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1560

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1620

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1680

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1740

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1800

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1070
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1070
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      480

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      540

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      600

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      660

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      720

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      780

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      840

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc      900

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua      960

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug     1020

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1080

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1140

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1200

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1260

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1320

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1380

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1440

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1500

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1560

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1620

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1680

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1740

aucgcuguag gccuucuguu guacugcaag gccaggucua cacccgugac gcucagcaag     1800

gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1071
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1071
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      480

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      540

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      600

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      660

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      720

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      780

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      840

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      960

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug     1020

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1080

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1140

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1200

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1260

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1320

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1380

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1500

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1560

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1680

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1740

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1800

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1072
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1072
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      480

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      540

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      600

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      660

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      720

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      780

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      840

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc      900

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug      960

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc     1020

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1080

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1140

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1200

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1260

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1320

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1380

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1440

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1500

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1560

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1620

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1680

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1740

aucgcggucg ggcugcuccu guacugcaag gcccggucca cccccgugac gcuuagcaag     1800

gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu gaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1073
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1073
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc uaacagcagu cacauucugc      180

uucgccucag gccaaaacau uacagaagaa uuuuaccaau caacaugcuc ugccguauca      240

aaaggcuacc uauccgcccu acgaacaggc ugguacacaa gcguaauaac aaucgaacua      300

ucaaacauaa aagaaaacaa augcaacggu acagacgcca aaguuaaacu aauaaaacaa      360

gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aucaacaccu      420

gcaacaaaca auagagccag gagagaauua ccucgauuca ugaauuacac acucaauaac      480

gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac gacgauucuu aggauuccua      540

cucggagucg gaucagcaau agcaucuggc guugcaguau gcaaaguauu acacuuagaa      600

ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa acaaagcagu cgucucccua      660

ucaaacggag ucucaguccu aacauucaaa guacucgacc uaaaaaauua cauagauaaa      720

caacuacuuc caauauuaaa caaacaaucc uguagcauca gcaauauaga aacaguaaua      780

gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc gagaauuuuc cguaaacgcc      840

gggguaacaa cuccagucuc aaccuacaug cuaaccaauu cagaacuauu gagcuuaaua      900

aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu cuaacaaugu ucaaaucguc      960

agacaacaaa guuacaguau aauguguaua aucaaagaag aaguccuagc auacguaguc     1020

caacucccac uauauggagu uaucgacaca ccauguugga aauuacacac cucaccauua     1080

ugcacaacca auacaaaaga aggaucaaac auaugccuua cacggacaga ccgcggaugg     1140

uauugugaca acgcuggcuc agucuccuuu uucccacaag cagaaacaug caaaguacaa     1200

ucaaacagag ucuuuugcga uaccaugaac ucacuuacau uaccaagcga aguaaaucuu     1260

uguaacgucg acaucuucaa uccuaaauau gacugcaaaa ucaugaccuc aaaaacagac     1320

guuagcucuu caguaaucac uagcuuagga gcaaucguau caugcuacgg caaaacaaaa     1380

uguacagcau caaauaaaaa cagaggaauc auaaaaacau uuucaaacgg augcgauuau     1440

guaagcaaca aaggaguaga uacuguaagc guaggaaaca cauuguacua uguaaacaaa     1500

caagaaggaa aaucacucua uguaaaagga gaaccuauaa ucaauuucua cgauccauua     1560

guguucccau cagaugaauu ugacgccuca auaucacaag uuaaugaaaa aauaaaucaa     1620

ucgcuagcau ucauacguaa aucagaugaa uuacuacaua acguaaacgc aggcaaaucc     1680

acaacaaaua ucaugaucac aacaauuaua auaguaauaa uaguaauacu acuaucacua     1740

auagccguag gacuccuacu auacugcaaa gcaagaucua cuccaguaac ccucucaaaa     1800

gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu aaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1074
<211>  2054
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1074
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuua uccucaaagc caacgccauc accaccaucc ucacagcagu aaccuuuugc      180

uucgccucag gccaaaauau cacagaagaa uuuuaccaga guaccugcuc cgccguaucc      240

aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu caguaaucac aaucgaacua      300

uccaacauca aagaaaacaa augcaacggc accgacgcga aagucaaacu caucaaacaa      360

gaacuagaca aauacaaaaa ugccguaaca gaacuacaac uguuaaugca gagcacaccc      420

gccaccaaca accgcgcccg ccgggaacuc ccccgauuca ugaacuacac acucaacaac      480

gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac gcagauuccu cgguuuccua      540

cuaggcguag gcucagcaau agccuccgga guagccgucu gcaaaguccu gcacuuagaa      600

ggcgaaguca acaaaaucaa auccgcccua cucuccacga acaaagccgu cgucucccug      660

uccaacggug ucuccguuuu aaccuucaaa guucuggacc ucaaaaacua cauagacaaa      720

cagcuucucc ccauccucaa caaacaaucc uguagcaucu ccaacaucga aaccgucaua      780

gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc gcgaguucuc cgucaacgcc      840

ggcgucacga cucccgucuc caccuauaug cucacgaacu cggaacuccu uucccuaauc      900

aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaauuguc      960

cgccaacaau cauacuccau caugugcaua auuaaagaag aaguccucgc auacguaguc     1020

caacuccccc ucuacggcgu caucgacacc cccugcugga aacuccacac cuccccacuc     1080

ugcacaacca acaccaaaga aggcucaaac auaugccuaa cgcgcaccga ucgcgguugg     1140

uacugcgaca acgccgguuc cgucagcuuc uucccccaag cagagacaug caaaguccaa     1200

ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc uuccaagcga agucaaccuc     1260

ugcaacguug acaucuucaa ccccaaauac gacuguaaaa ucaugaccuc caagaccgac     1320

guauccucuu ccgucaucac aucccuaggc gcuaucguau ccugcuaugg uaaaaccaaa     1380

ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau uuuccaacgg cugcgacuac     1440

gugagcaaca aaggcgucga caccgucucc guaggcaaca cccucuacua uguaaacaaa     1500

caagagggca aaucacucua cgucaaaggg gaacccauca ucaacuucua cgacccgcuc     1560

guauucccca gcgaugaguu cgacgccucc aucucccagg ucaacgaaaa gauaaaccaa     1620

ucacucgcau ucauucguaa auccgacgaa cuccuacaca acgugaaugc aggcaaaucg     1680

accacuaaca ucaugaucac caccaucauc aucgucauca uagucauccu ccugucccuu     1740

aucgccgucg gucuuuuauu auacugcaaa gcccgcagca cccccgucac ccucucuaag     1800

gaccaacuca gcggcaucaa uaacaucgca uucucuaacu aaggacuagu guccaccugu     1860

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1920

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2040

gagccaccag aauu                                                       2054


<210>  1075
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1075
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1076
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1076
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcuc cacgcccgug acccugagca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1077
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1077
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1078
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1078
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccagguc uacacccgug acgcucagca aggaccagcu guccgggaua     1800

aacaauaucg cuuuuucaaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1079
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1079
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1080
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1080
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccgguc cacccccgug acgcuuagca aggaccagcu gucuggaauu     1800

aacaauaucg cuuuuuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1081
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1081
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuauu aauccucaaa      120

gcgaacgcua uuacuaccau ucuaacagca gucacauucu gcuucgccuc aggccaaaac      180

auuacagaag aauuuuacca aucaacaugc ucugccguau caaaaggcua ccuauccgcc      240

cuacgaacag gcugguacac aagcguaaua acaaucgaac uaucaaacau aaaagaaaac      300

aaaugcaacg guacagacgc caaaguuaaa cuaauaaaac aagaacucga uaaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaucaacac cugcaacaaa caauagagcc      420

aggagagaau uaccucgauu caugaauuac acacucaaua acgcaaaaaa aaccaacguu      480

acacuaucaa aaaaaagaaa acgacgauuc uuaggauucc uacucggagu cggaucagca      540

auagcaucug gcguugcagu augcaaagua uuacacuuag aaggugaagu caauaaaaua      600

aaaagcgcgc uacuaaguac aaacaaagca gucgucuccc uaucaaacgg agucucaguc      660

cuaacauuca aaguacucga ccuaaaaaau uacauagaua aacaacuacu uccaauauua      720

aacaaacaau ccuguagcau cagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      780

aaccgauuau uagaaaucac ucgagaauuu uccguaaacg ccgggguaac aacuccaguc      840

ucaaccuaca ugcuaaccaa uucagaacua uugagcuuaa uaaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gucuaacaau guucaaaucg ucagacaaca aaguuacagu      960

auaaugugua uaaucaaaga agaaguccua gcauacguag uccaacuccc acuauaugga     1020

guuaucgaca caccauguug gaaauuacac accucaccau uaugcacaac caauacaaaa     1080

gaaggaucaa acauaugccu uacacggaca gaccgcggau gguauuguga caacgcuggc     1140

ucagucuccu uuuucccaca agcagaaaca ugcaaaguac aaucaaacag agucuuuugc     1200

gauaccauga acucacuuac auuaccaagc gaaguaaauc uuuguaacgu cgacaucuuc     1260

aauccuaaau augacugcaa aaucaugacc ucaaaaacag acguuagcuc uucaguaauc     1320

acuagcuuag gagcaaucgu aucaugcuac ggcaaaacaa aauguacagc aucaaauaaa     1380

aacagaggaa ucauaaaaac auuuucaaac ggaugcgauu auguaagcaa caaaggagua     1440

gauacuguaa gcguaggaaa cacauuguac uauguaaaca aacaagaagg aaaaucacuc     1500

uauguaaaag gagaaccuau aaucaauuuc uacgauccau uaguguuccc aucagaugaa     1560

uuugacgccu caauaucaca aguuaaugaa aaaauaaauc aaucgcuagc auucauacgu     1620

aaaucagaug aauuacuaca uaacguaaac gcaggcaaau ccacaacaaa uaucaugauc     1680

acaacaauua uaauaguaau aauaguaaua cuacuaucac uaauagccgu aggacuccua     1740

cuauacugca aagcaagauc uacuccagua acccucucaa aagaucaacu aagcggaauu     1800

aauaacaucg cauucagcaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1082
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1082
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu uauccucaaa      120

gccaacgcca ucaccaccau ccucacagca guaaccuuuu gcuucgccuc aggccaaaau      180

aucacagaag aauuuuacca gaguaccugc uccgccguau ccaaaggaua ccucagcgcg      240

cuccgcaccg gcugguacac uucaguaauc acaaucgaac uauccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aaugccguaa cagaacuaca acuguuaaug cagagcacac ccgccaccaa caaccgcgcc      420

cgccgggaac ucccccgauu caugaacuac acacucaaca acgccaaaaa gacgaacguc      480

acccucagca agaaacgaaa acgcagauuc cucgguuucc uacuaggcgu aggcucagca      540

auagccuccg gaguagccgu cugcaaaguc cugcacuuag aaggcgaagu caacaaaauc      600

aaauccgccc uacucuccac gaacaaagcc gucgucuccc uguccaacgg ugucuccguu      660

uuaaccuuca aaguucugga ccucaaaaac uacauagaca aacagcuucu ccccauccuc      720

aacaaacaau ccuguagcau cuccaacauc gaaaccguca uagaauuuca acagaaaaac      780

aacagacugc ucgaaaucac ccgcgaguuc uccgucaacg ccggcgucac gacucccguc      840

uccaccuaua ugcucacgaa cucggaacuc cuuucccuaa ucaacgacau gccgaucacc      900

aacgaccaaa agaaacucau gucaaacaac guacaaauug uccgccaaca aucauacucc      960

aucaugugca uaauuaaaga agaaguccuc gcauacguag uccaacuccc ccucuacggc     1020

gucaucgaca cccccugcug gaaacuccac accuccccac ucugcacaac caacaccaaa     1080

gaaggcucaa acauaugccu aacgcgcacc gaucgcgguu gguacugcga caacgccggu     1140

uccgucagcu ucuuccccca agcagagaca ugcaaagucc aaucaaaccg cgucuucugc     1200

gacaccauga acucacuaac ccuuccaagc gaagucaacc ucugcaacgu ugacaucuuc     1260

aaccccaaau acgacuguaa aaucaugacc uccaagaccg acguauccuc uuccgucauc     1320

acaucccuag gcgcuaucgu auccugcuau gguaaaacca aaugcaccgc cuccaacaaa     1380

aaccgcggca ucaucaagac auuuuccaac ggcugcgacu acgugagcaa caaaggcguc     1440

gacaccgucu ccguaggcaa cacccucuac uauguaaaca aacaagaggg caaaucacuc     1500

uacgucaaag gggaacccau caucaacuuc uacgacccgc ucguauuccc cagcgaugag     1560

uucgacgccu ccaucuccca ggucaacgaa aagauaaacc aaucacucgc auucauucgu     1620

aaauccgacg aacuccuaca caacgugaau gcaggcaaau cgaccacuaa caucaugauc     1680

accaccauca ucaucgucau cauagucauc cuccuguccc uuaucgccgu cggucuuuua     1740

uuauacugca aagcccgcag cacccccguc acccucucua aggaccaacu cagcggcauc     1800

aauaacaucg cauucucuaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1860

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1083
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1083
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1084
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1084
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcuc cacgcccgug     1740

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1085
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1085
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1086
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1086
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccagguc uacacccgug     1740

acgcucagca aggaccagcu guccgggaua aacaauaucg cuuuuucaaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1087
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1087
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1088
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1088
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccgguc cacccccgug     1740

acgcuuagca aggaccagcu gucuggaauu aacaauaucg cuuuuuccaa cugaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1089
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1089
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuauu aauccucaaa gcgaacgcua uuacuaccau ucuaacagca      120

gucacauucu gcuucgccuc aggccaaaac auuacagaag aauuuuacca aucaacaugc      180

ucugccguau caaaaggcua ccuauccgcc cuacgaacag gcugguacac aagcguaaua      240

acaaucgaac uaucaaacau aaaagaaaac aaaugcaacg guacagacgc caaaguuaaa      300

cuaauaaaac aagaacucga uaaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaucaacac cugcaacaaa caauagagcc aggagagaau uaccucgauu caugaauuac      420

acacucaaua acgcaaaaaa aaccaacguu acacuaucaa aaaaaagaaa acgacgauuc      480

uuaggauucc uacucggagu cggaucagca auagcaucug gcguugcagu augcaaagua      540

uuacacuuag aaggugaagu caauaaaaua aaaagcgcgc uacuaaguac aaacaaagca      600

gucgucuccc uaucaaacgg agucucaguc cuaacauuca aaguacucga ccuaaaaaau      660

uacauagaua aacaacuacu uccaauauua aacaaacaau ccuguagcau cagcaauaua      720

gaaacaguaa uagaauuuca acaaaaaaac aaccgauuau uagaaaucac ucgagaauuu      780

uccguaaacg ccgggguaac aacuccaguc ucaaccuaca ugcuaaccaa uucagaacua      840

uugagcuuaa uaaacgacau gccaauaacc aacgaccaaa aaaaacuaau gucuaacaau      900

guucaaaucg ucagacaaca aaguuacagu auaaugugua uaaucaaaga agaaguccua      960

gcauacguag uccaacuccc acuauaugga guuaucgaca caccauguug gaaauuacac     1020

accucaccau uaugcacaac caauacaaaa gaaggaucaa acauaugccu uacacggaca     1080

gaccgcggau gguauuguga caacgcuggc ucagucuccu uuuucccaca agcagaaaca     1140

ugcaaaguac aaucaaacag agucuuuugc gauaccauga acucacuuac auuaccaagc     1200

gaaguaaauc uuuguaacgu cgacaucuuc aauccuaaau augacugcaa aaucaugacc     1260

ucaaaaacag acguuagcuc uucaguaauc acuagcuuag gagcaaucgu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaauaaa aacagaggaa ucauaaaaac auuuucaaac     1380

ggaugcgauu auguaagcaa caaaggagua gauacuguaa gcguaggaaa cacauuguac     1440

uauguaaaca aacaagaagg aaaaucacuc uauguaaaag gagaaccuau aaucaauuuc     1500

uacgauccau uaguguuccc aucagaugaa uuugacgccu caauaucaca aguuaaugaa     1560

aaaauaaauc aaucgcuagc auucauacgu aaaucagaug aauuacuaca uaacguaaac     1620

gcaggcaaau ccacaacaaa uaucaugauc acaacaauua uaauaguaau aauaguaaua     1680

cuacuaucac uaauagccgu aggacuccua cuauacugca aagcaagauc uacuccagua     1740

acccucucaa aagaucaacu aagcggaauu aauaacaucg cauucagcaa cuaaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1090
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1090
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu uauccucaaa gccaacgcca ucaccaccau ccucacagca      120

guaaccuuuu gcuucgccuc aggccaaaau aucacagaag aauuuuacca gaguaccugc      180

uccgccguau ccaaaggaua ccucagcgcg cuccgcaccg gcugguacac uucaguaauc      240

acaaucgaac uauccaacau caaagaaaac aaaugcaacg gcaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aaugccguaa cagaacuaca acuguuaaug      360

cagagcacac ccgccaccaa caaccgcgcc cgccgggaac ucccccgauu caugaacuac      420

acacucaaca acgccaaaaa gacgaacguc acccucagca agaaacgaaa acgcagauuc      480

cucgguuucc uacuaggcgu aggcucagca auagccuccg gaguagccgu cugcaaaguc      540

cugcacuuag aaggcgaagu caacaaaauc aaauccgccc uacucuccac gaacaaagcc      600

gucgucuccc uguccaacgg ugucuccguu uuaaccuuca aaguucugga ccucaaaaac      660

uacauagaca aacagcuucu ccccauccuc aacaaacaau ccuguagcau cuccaacauc      720

gaaaccguca uagaauuuca acagaaaaac aacagacugc ucgaaaucac ccgcgaguuc      780

uccgucaacg ccggcgucac gacucccguc uccaccuaua ugcucacgaa cucggaacuc      840

cuuucccuaa ucaacgacau gccgaucacc aacgaccaaa agaaacucau gucaaacaac      900

guacaaauug uccgccaaca aucauacucc aucaugugca uaauuaaaga agaaguccuc      960

gcauacguag uccaacuccc ccucuacggc gucaucgaca cccccugcug gaaacuccac     1020

accuccccac ucugcacaac caacaccaaa gaaggcucaa acauaugccu aacgcgcacc     1080

gaucgcgguu gguacugcga caacgccggu uccgucagcu ucuuccccca agcagagaca     1140

ugcaaagucc aaucaaaccg cgucuucugc gacaccauga acucacuaac ccuuccaagc     1200

gaagucaacc ucugcaacgu ugacaucuuc aaccccaaau acgacuguaa aaucaugacc     1260

uccaagaccg acguauccuc uuccgucauc acaucccuag gcgcuaucgu auccugcuau     1320

gguaaaacca aaugcaccgc cuccaacaaa aaccgcggca ucaucaagac auuuuccaac     1380

ggcugcgacu acgugagcaa caaaggcguc gacaccgucu ccguaggcaa cacccucuac     1440

uauguaaaca aacaagaggg caaaucacuc uacgucaaag gggaacccau caucaacuuc     1500

uacgacccgc ucguauuccc cagcgaugag uucgacgccu ccaucuccca ggucaacgaa     1560

aagauaaacc aaucacucgc auucauucgu aaauccgacg aacuccuaca caacgugaau     1620

gcaggcaaau cgaccacuaa caucaugauc accaccauca ucaucgucau cauagucauc     1680

cuccuguccc uuaucgccgu cggucuuuua uuauacugca aagcccgcag cacccccguc     1740

acccucucua aggaccaacu cagcggcauc aauaacaucg cauucucuaa cuaaggacua     1800

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1860

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1091
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1091
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1092
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1092
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcuccacgcc cgugacccug     1800

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1093
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1093
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1094
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1094
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggucuacacc cgugacgcuc     1800

agcaaggacc agcuguccgg gauaaacaau aucgcuuuuu caaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1095
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1095
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1096
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1096
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc gguccacccc cgugacgcuu     1800

agcaaggacc agcugucugg aauuaacaau aucgcuuuuu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1097
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1097
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uauuaauccu caaagcgaac gcuauuacua ccauucuaac agcagucaca      180

uucugcuucg ccucaggcca aaacauuaca gaagaauuuu accaaucaac augcucugcc      240

guaucaaaag gcuaccuauc cgcccuacga acaggcuggu acacaagcgu aauaacaauc      300

gaacuaucaa acauaaaaga aaacaaaugc aacgguacag acgccaaagu uaaacuaaua      360

aaacaagaac ucgauaaaua caaaaacgca guaacagaau uacaacuacu aaugcaauca      420

acaccugcaa caaacaauag agccaggaga gaauuaccuc gauucaugaa uuacacacuc      480

aauaacgcaa aaaaaaccaa cguuacacua ucaaaaaaaa gaaaacgacg auucuuagga      540

uuccuacucg gagucggauc agcaauagca ucuggcguug caguaugcaa aguauuacac      600

uuagaaggug aagucaauaa aauaaaaagc gcgcuacuaa guacaaacaa agcagucguc      660

ucccuaucaa acggagucuc aguccuaaca uucaaaguac ucgaccuaaa aaauuacaua      720

gauaaacaac uacuuccaau auuaaacaaa caauccugua gcaucagcaa uauagaaaca      780

guaauagaau uucaacaaaa aaacaaccga uuauuagaaa ucacucgaga auuuuccgua      840

aacgccgggg uaacaacucc agucucaacc uacaugcuaa ccaauucaga acuauugagc      900

uuaauaaacg acaugccaau aaccaacgac caaaaaaaac uaaugucuaa caauguucaa      960

aucgucagac aacaaaguua caguauaaug uguauaauca aagaagaagu ccuagcauac     1020

guaguccaac ucccacuaua uggaguuauc gacacaccau guuggaaauu acacaccuca     1080

ccauuaugca caaccaauac aaaagaagga ucaaacauau gccuuacacg gacagaccgc     1140

ggaugguauu gugacaacgc uggcucaguc uccuuuuucc cacaagcaga aacaugcaaa     1200

guacaaucaa acagagucuu uugcgauacc augaacucac uuacauuacc aagcgaagua     1260

aaucuuugua acgucgacau cuucaauccu aaauaugacu gcaaaaucau gaccucaaaa     1320

acagacguua gcucuucagu aaucacuagc uuaggagcaa ucguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa uaaaaacaga ggaaucauaa aaacauuuuc aaacggaugc     1440

gauuauguaa gcaacaaagg aguagauacu guaagcguag gaaacacauu guacuaugua     1500

aacaaacaag aaggaaaauc acucuaugua aaaggagaac cuauaaucaa uuucuacgau     1560

ccauuagugu ucccaucaga ugaauuugac gccucaauau cacaaguuaa ugaaaaaaua     1620

aaucaaucgc uagcauucau acguaaauca gaugaauuac uacauaacgu aaacgcaggc     1680

aaauccacaa caaauaucau gaucacaaca auuauaauag uaauaauagu aauacuacua     1740

ucacuaauag ccguaggacu ccuacuauac ugcaaagcaa gaucuacucc aguaacccuc     1800

ucaaaagauc aacuaagcgg aauuaauaac aucgcauuca gcaacuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1098
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1098
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuuauccu caaagccaac gccaucacca ccauccucac agcaguaacc      180

uuuugcuucg ccucaggcca aaauaucaca gaagaauuuu accagaguac cugcuccgcc      240

guauccaaag gauaccucag cgcgcuccgc accggcuggu acacuucagu aaucacaauc      300

gaacuaucca acaucaaaga aaacaaaugc aacggcaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaaugcc guaacagaac uacaacuguu aaugcagagc      420

acacccgcca ccaacaaccg cgcccgccgg gaacuccccc gauucaugaa cuacacacuc      480

aacaacgcca aaaagacgaa cgucacccuc agcaagaaac gaaaacgcag auuccucggu      540

uuccuacuag gcguaggcuc agcaauagcc uccggaguag ccgucugcaa aguccugcac      600

uuagaaggcg aagucaacaa aaucaaaucc gcccuacucu ccacgaacaa agccgucguc      660

ucccugucca acggugucuc cguuuuaacc uucaaaguuc uggaccucaa aaacuacaua      720

gacaaacagc uucuccccau ccucaacaaa caauccugua gcaucuccaa caucgaaacc      780

gucauagaau uucaacagaa aaacaacaga cugcucgaaa ucacccgcga guucuccguc      840

aacgccggcg ucacgacucc cgucuccacc uauaugcuca cgaacucgga acuccuuucc      900

cuaaucaacg acaugccgau caccaacgac caaaagaaac ucaugucaaa caacguacaa      960

auuguccgcc aacaaucaua cuccaucaug ugcauaauua aagaagaagu ccucgcauac     1020

guaguccaac ucccccucua cggcgucauc gacacccccu gcuggaaacu ccacaccucc     1080

ccacucugca caaccaacac caaagaaggc ucaaacauau gccuaacgcg caccgaucgc     1140

gguugguacu gcgacaacgc cgguuccguc agcuucuucc cccaagcaga gacaugcaaa     1200

guccaaucaa accgcgucuu cugcgacacc augaacucac uaacccuucc aagcgaaguc     1260

aaccucugca acguugacau cuucaacccc aaauacgacu guaaaaucau gaccuccaag     1320

accgacguau ccucuuccgu caucacaucc cuaggcgcua ucguauccug cuaugguaaa     1380

accaaaugca ccgccuccaa caaaaaccgc ggcaucauca agacauuuuc caacggcugc     1440

gacuacguga gcaacaaagg cgucgacacc gucuccguag gcaacacccu cuacuaugua     1500

aacaaacaag agggcaaauc acucuacguc aaaggggaac ccaucaucaa cuucuacgac     1560

ccgcucguau uccccagcga ugaguucgac gccuccaucu cccaggucaa cgaaaagaua     1620

aaccaaucac ucgcauucau ucguaaaucc gacgaacucc uacacaacgu gaaugcaggc     1680

aaaucgacca cuaacaucau gaucaccacc aucaucaucg ucaucauagu cauccuccug     1740

ucccuuaucg ccgucggucu uuuauuauac ugcaaagccc gcagcacccc cgucacccuc     1800

ucuaaggacc aacucagcgg caucaauaac aucgcauucu cuaacuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1099
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1099
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1100
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1100
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu ccacgcccgu gacccugagc aaggaccagc ucuccggcau caacaacauc     1800

gccuucagca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1101
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1101
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1102
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1102
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu cuacacccgu gacgcucagc aaggaccagc uguccgggau aaacaauauc     1800

gcuuuuucaa acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1103
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1103
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1104
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1104
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu ccacccccgu gacgcuuagc aaggaccagc ugucuggaau uaacaauauc     1800

gcuuuuucca acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1105
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1105
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuau uaauccucaa agcgaacgcu      120

auuacuacca uucuaacagc agucacauuc ugcuucgccu caggccaaaa cauuacagaa      180

gaauuuuacc aaucaacaug cucugccgua ucaaaaggcu accuauccgc ccuacgaaca      240

ggcugguaca caagcguaau aacaaucgaa cuaucaaaca uaaaagaaaa caaaugcaac      300

gguacagacg ccaaaguuaa acuaauaaaa caagaacucg auaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaucaaca ccugcaacaa acaauagagc caggagagaa      420

uuaccucgau ucaugaauua cacacucaau aacgcaaaaa aaaccaacgu uacacuauca      480

aaaaaaagaa aacgacgauu cuuaggauuc cuacucggag ucggaucagc aauagcaucu      540

ggcguugcag uaugcaaagu auuacacuua gaaggugaag ucaauaaaau aaaaagcgcg      600

cuacuaagua caaacaaagc agucgucucc cuaucaaacg gagucucagu ccuaacauuc      660

aaaguacucg accuaaaaaa uuacauagau aaacaacuac uuccaauauu aaacaaacaa      720

uccuguagca ucagcaauau agaaacagua auagaauuuc aacaaaaaaa caaccgauua      780

uuagaaauca cucgagaauu uuccguaaac gccgggguaa caacuccagu cucaaccuac      840

augcuaacca auucagaacu auugagcuua auaaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugucuaacaa uguucaaauc gucagacaac aaaguuacag uauaaugugu      960

auaaucaaag aagaaguccu agcauacgua guccaacucc cacuauaugg aguuaucgac     1020

acaccauguu ggaaauuaca caccucacca uuaugcacaa ccaauacaaa agaaggauca     1080

aacauaugcc uuacacggac agaccgcgga ugguauugug acaacgcugg cucagucucc     1140

uuuuucccac aagcagaaac augcaaagua caaucaaaca gagucuuuug cgauaccaug     1200

aacucacuua cauuaccaag cgaaguaaau cuuuguaacg ucgacaucuu caauccuaaa     1260

uaugacugca aaaucaugac cucaaaaaca gacguuagcu cuucaguaau cacuagcuua     1320

ggagcaaucg uaucaugcua cggcaaaaca aaauguacag caucaaauaa aaacagagga     1380

aucauaaaaa cauuuucaaa cggaugcgau uauguaagca acaaaggagu agauacugua     1440

agcguaggaa acacauugua cuauguaaac aaacaagaag gaaaaucacu cuauguaaaa     1500

ggagaaccua uaaucaauuu cuacgaucca uuaguguucc caucagauga auuugacgcc     1560

ucaauaucac aaguuaauga aaaaauaaau caaucgcuag cauucauacg uaaaucagau     1620

gaauuacuac auaacguaaa cgcaggcaaa uccacaacaa auaucaugau cacaacaauu     1680

auaauaguaa uaauaguaau acuacuauca cuaauagccg uaggacuccu acuauacugc     1740

aaagcaagau cuacuccagu aacccucuca aaagaucaac uaagcggaau uaauaacauc     1800

gcauucagca acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1106
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1106
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uuauccucaa agccaacgcc      120

aucaccacca uccucacagc aguaaccuuu ugcuucgccu caggccaaaa uaucacagaa      180

gaauuuuacc agaguaccug cuccgccgua uccaaaggau accucagcgc gcuccgcacc      240

ggcugguaca cuucaguaau cacaaucgaa cuauccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg cgaaagucaa acucaucaaa caagaacuag acaaauacaa aaaugccgua      360

acagaacuac aacuguuaau gcagagcaca cccgccacca acaaccgcgc ccgccgggaa      420

cucccccgau ucaugaacua cacacucaac aacgccaaaa agacgaacgu cacccucagc      480

aagaaacgaa aacgcagauu ccucgguuuc cuacuaggcg uaggcucagc aauagccucc      540

ggaguagccg ucugcaaagu ccugcacuua gaaggcgaag ucaacaaaau caaauccgcc      600

cuacucucca cgaacaaagc cgucgucucc cuguccaacg gugucuccgu uuuaaccuuc      660

aaaguucugg accucaaaaa cuacauagac aaacagcuuc uccccauccu caacaaacaa      720

uccuguagca ucuccaacau cgaaaccguc auagaauuuc aacagaaaaa caacagacug      780

cucgaaauca cccgcgaguu cuccgucaac gccggcguca cgacucccgu cuccaccuau      840

augcucacga acucggaacu ccuuucccua aucaacgaca ugccgaucac caacgaccaa      900

aagaaacuca ugucaaacaa cguacaaauu guccgccaac aaucauacuc caucaugugc      960

auaauuaaag aagaaguccu cgcauacgua guccaacucc cccucuacgg cgucaucgac     1020

acccccugcu ggaaacucca caccucccca cucugcacaa ccaacaccaa agaaggcuca     1080

aacauaugcc uaacgcgcac cgaucgcggu ugguacugcg acaacgccgg uuccgucagc     1140

uucuuccccc aagcagagac augcaaaguc caaucaaacc gcgucuucug cgacaccaug     1200

aacucacuaa cccuuccaag cgaagucaac cucugcaacg uugacaucuu caaccccaaa     1260

uacgacugua aaaucaugac cuccaagacc gacguauccu cuuccgucau cacaucccua     1320

ggcgcuaucg uauccugcua ugguaaaacc aaaugcaccg ccuccaacaa aaaccgcggc     1380

aucaucaaga cauuuuccaa cggcugcgac uacgugagca acaaaggcgu cgacaccguc     1440

uccguaggca acacccucua cuauguaaac aaacaagagg gcaaaucacu cuacgucaaa     1500

ggggaaccca ucaucaacuu cuacgacccg cucguauucc ccagcgauga guucgacgcc     1560

uccaucuccc aggucaacga aaagauaaac caaucacucg cauucauucg uaaauccgac     1620

gaacuccuac acaacgugaa ugcaggcaaa ucgaccacua acaucaugau caccaccauc     1680

aucaucguca ucauagucau ccuccugucc cuuaucgccg ucggucuuuu auuauacugc     1740

aaagcccgca gcacccccgu cacccucucu aaggaccaac ucagcggcau caauaacauc     1800

gcauucucua acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1860

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1107
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1107
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1108
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1108
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu ccacgcccgu gacccugagc aaggaccagc ucuccggcau caacaacauc     1800

gccuucagca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1109
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1109
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1110
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1110
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu cuacacccgu gacgcucagc aaggaccagc uguccgggau aaacaauauc     1800

gcuuuuucaa acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1111
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1111
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1112
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1112
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu ccacccccgu gacgcuuagc aaggaccagc ugucuggaau uaacaauauc     1800

gcuuuuucca acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1113
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1113
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuau uaauccucaa agcgaacgcu      120

auuacuacca uucuaacagc agucacauuc ugcuucgccu caggccaaaa cauuacagaa      180

gaauuuuacc aaucaacaug cucugccgua ucaaaaggcu accuauccgc ccuacgaaca      240

ggcugguaca caagcguaau aacaaucgaa cuaucaaaca uaaaagaaaa caaaugcaac      300

gguacagacg ccaaaguuaa acuaauaaaa caagaacucg auaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaucaaca ccugcaacaa acaauagagc caggagagaa      420

uuaccucgau ucaugaauua cacacucaau aacgcaaaaa aaaccaacgu uacacuauca      480

aaaaaaagaa aacgacgauu cuuaggauuc cuacucggag ucggaucagc aauagcaucu      540

ggcguugcag uaugcaaagu auuacacuua gaaggugaag ucaauaaaau aaaaagcgcg      600

cuacuaagua caaacaaagc agucgucucc cuaucaaacg gagucucagu ccuaacauuc      660

aaaguacucg accuaaaaaa uuacauagau aaacaacuac uuccaauauu aaacaaacaa      720

uccuguagca ucagcaauau agaaacagua auagaauuuc aacaaaaaaa caaccgauua      780

uuagaaauca cucgagaauu uuccguaaac gccgggguaa caacuccagu cucaaccuac      840

augcuaacca auucagaacu auugagcuua auaaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugucuaacaa uguucaaauc gucagacaac aaaguuacag uauaaugugu      960

auaaucaaag aagaaguccu agcauacgua guccaacucc cacuauaugg aguuaucgac     1020

acaccauguu ggaaauuaca caccucacca uuaugcacaa ccaauacaaa agaaggauca     1080

aacauaugcc uuacacggac agaccgcgga ugguauugug acaacgcugg cucagucucc     1140

uuuuucccac aagcagaaac augcaaagua caaucaaaca gagucuuuug cgauaccaug     1200

aacucacuua cauuaccaag cgaaguaaau cuuuguaacg ucgacaucuu caauccuaaa     1260

uaugacugca aaaucaugac cucaaaaaca gacguuagcu cuucaguaau cacuagcuua     1320

ggagcaaucg uaucaugcua cggcaaaaca aaauguacag caucaaauaa aaacagagga     1380

aucauaaaaa cauuuucaaa cggaugcgau uauguaagca acaaaggagu agauacugua     1440

agcguaggaa acacauugua cuauguaaac aaacaagaag gaaaaucacu cuauguaaaa     1500

ggagaaccua uaaucaauuu cuacgaucca uuaguguucc caucagauga auuugacgcc     1560

ucaauaucac aaguuaauga aaaaauaaau caaucgcuag cauucauacg uaaaucagau     1620

gaauuacuac auaacguaaa cgcaggcaaa uccacaacaa auaucaugau cacaacaauu     1680

auaauaguaa uaauaguaau acuacuauca cuaauagccg uaggacuccu acuauacugc     1740

aaagcaagau cuacuccagu aacccucuca aaagaucaac uaagcggaau uaauaacauc     1800

gcauucagca acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1114
<211>  2094
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1114
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uuauccucaa agccaacgcc      120

aucaccacca uccucacagc aguaaccuuu ugcuucgccu caggccaaaa uaucacagaa      180

gaauuuuacc agaguaccug cuccgccgua uccaaaggau accucagcgc gcuccgcacc      240

ggcugguaca cuucaguaau cacaaucgaa cuauccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg cgaaagucaa acucaucaaa caagaacuag acaaauacaa aaaugccgua      360

acagaacuac aacuguuaau gcagagcaca cccgccacca acaaccgcgc ccgccgggaa      420

cucccccgau ucaugaacua cacacucaac aacgccaaaa agacgaacgu cacccucagc      480

aagaaacgaa aacgcagauu ccucgguuuc cuacuaggcg uaggcucagc aauagccucc      540

ggaguagccg ucugcaaagu ccugcacuua gaaggcgaag ucaacaaaau caaauccgcc      600

cuacucucca cgaacaaagc cgucgucucc cuguccaacg gugucuccgu uuuaaccuuc      660

aaaguucugg accucaaaaa cuacauagac aaacagcuuc uccccauccu caacaaacaa      720

uccuguagca ucuccaacau cgaaaccguc auagaauuuc aacagaaaaa caacagacug      780

cucgaaauca cccgcgaguu cuccgucaac gccggcguca cgacucccgu cuccaccuau      840

augcucacga acucggaacu ccuuucccua aucaacgaca ugccgaucac caacgaccaa      900

aagaaacuca ugucaaacaa cguacaaauu guccgccaac aaucauacuc caucaugugc      960

auaauuaaag aagaaguccu cgcauacgua guccaacucc cccucuacgg cgucaucgac     1020

acccccugcu ggaaacucca caccucccca cucugcacaa ccaacaccaa agaaggcuca     1080

aacauaugcc uaacgcgcac cgaucgcggu ugguacugcg acaacgccgg uuccgucagc     1140

uucuuccccc aagcagagac augcaaaguc caaucaaacc gcgucuucug cgacaccaug     1200

aacucacuaa cccuuccaag cgaagucaac cucugcaacg uugacaucuu caaccccaaa     1260

uacgacugua aaaucaugac cuccaagacc gacguauccu cuuccgucau cacaucccua     1320

ggcgcuaucg uauccugcua ugguaaaacc aaaugcaccg ccuccaacaa aaaccgcggc     1380

aucaucaaga cauuuuccaa cggcugcgac uacgugagca acaaaggcgu cgacaccguc     1440

uccguaggca acacccucua cuauguaaac aaacaagagg gcaaaucacu cuacgucaaa     1500

ggggaaccca ucaucaacuu cuacgacccg cucguauucc ccagcgauga guucgacgcc     1560

uccaucuccc aggucaacga aaagauaaac caaucacucg cauucauucg uaaauccgac     1620

gaacuccuac acaacgugaa ugcaggcaaa ucgaccacua acaucaugau caccaccauc     1680

aucaucguca ucauagucau ccuccugucc cuuaucgccg ucggucuuuu auuauacugc     1740

aaagcccgca gcacccccgu cacccucucu aaggaccaac ucagcggcau caauaacauc     1800

gcauucucua acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1860

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1920

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2040

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2094


<210>  1115
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1115
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1116
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1116
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu ccacgcccgu gacccugagc aaggaccagc ucuccggcau caacaacauc     1800

gccuucagca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1117
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1117
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1118
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1118
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu cuacacccgu gacgcucagc aaggaccagc uguccgggau aaacaauauc     1800

gcuuuuucaa acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1119
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1119
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1120
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1120
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu ccacccccgu gacgcuuagc aaggaccagc ugucuggaau uaacaauauc     1800

gcuuuuucca acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1121
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1121
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuau uaauccucaa agcgaacgcu      120

auuacuacca uucuaacagc agucacauuc ugcuucgccu caggccaaaa cauuacagaa      180

gaauuuuacc aaucaacaug cucugccgua ucaaaaggcu accuauccgc ccuacgaaca      240

ggcugguaca caagcguaau aacaaucgaa cuaucaaaca uaaaagaaaa caaaugcaac      300

gguacagacg ccaaaguuaa acuaauaaaa caagaacucg auaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaucaaca ccugcaacaa acaauagagc caggagagaa      420

uuaccucgau ucaugaauua cacacucaau aacgcaaaaa aaaccaacgu uacacuauca      480

aaaaaaagaa aacgacgauu cuuaggauuc cuacucggag ucggaucagc aauagcaucu      540

ggcguugcag uaugcaaagu auuacacuua gaaggugaag ucaauaaaau aaaaagcgcg      600

cuacuaagua caaacaaagc agucgucucc cuaucaaacg gagucucagu ccuaacauuc      660

aaaguacucg accuaaaaaa uuacauagau aaacaacuac uuccaauauu aaacaaacaa      720

uccuguagca ucagcaauau agaaacagua auagaauuuc aacaaaaaaa caaccgauua      780

uuagaaauca cucgagaauu uuccguaaac gccgggguaa caacuccagu cucaaccuac      840

augcuaacca auucagaacu auugagcuua auaaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugucuaacaa uguucaaauc gucagacaac aaaguuacag uauaaugugu      960

auaaucaaag aagaaguccu agcauacgua guccaacucc cacuauaugg aguuaucgac     1020

acaccauguu ggaaauuaca caccucacca uuaugcacaa ccaauacaaa agaaggauca     1080

aacauaugcc uuacacggac agaccgcgga ugguauugug acaacgcugg cucagucucc     1140

uuuuucccac aagcagaaac augcaaagua caaucaaaca gagucuuuug cgauaccaug     1200

aacucacuua cauuaccaag cgaaguaaau cuuuguaacg ucgacaucuu caauccuaaa     1260

uaugacugca aaaucaugac cucaaaaaca gacguuagcu cuucaguaau cacuagcuua     1320

ggagcaaucg uaucaugcua cggcaaaaca aaauguacag caucaaauaa aaacagagga     1380

aucauaaaaa cauuuucaaa cggaugcgau uauguaagca acaaaggagu agauacugua     1440

agcguaggaa acacauugua cuauguaaac aaacaagaag gaaaaucacu cuauguaaaa     1500

ggagaaccua uaaucaauuu cuacgaucca uuaguguucc caucagauga auuugacgcc     1560

ucaauaucac aaguuaauga aaaaauaaau caaucgcuag cauucauacg uaaaucagau     1620

gaauuacuac auaacguaaa cgcaggcaaa uccacaacaa auaucaugau cacaacaauu     1680

auaauaguaa uaauaguaau acuacuauca cuaauagccg uaggacuccu acuauacugc     1740

aaagcaagau cuacuccagu aacccucuca aaagaucaac uaagcggaau uaauaacauc     1800

gcauucagca acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1122
<211>  2310
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1122
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uuauccucaa agccaacgcc      120

aucaccacca uccucacagc aguaaccuuu ugcuucgccu caggccaaaa uaucacagaa      180

gaauuuuacc agaguaccug cuccgccgua uccaaaggau accucagcgc gcuccgcacc      240

ggcugguaca cuucaguaau cacaaucgaa cuauccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg cgaaagucaa acucaucaaa caagaacuag acaaauacaa aaaugccgua      360

acagaacuac aacuguuaau gcagagcaca cccgccacca acaaccgcgc ccgccgggaa      420

cucccccgau ucaugaacua cacacucaac aacgccaaaa agacgaacgu cacccucagc      480

aagaaacgaa aacgcagauu ccucgguuuc cuacuaggcg uaggcucagc aauagccucc      540

ggaguagccg ucugcaaagu ccugcacuua gaaggcgaag ucaacaaaau caaauccgcc      600

cuacucucca cgaacaaagc cgucgucucc cuguccaacg gugucuccgu uuuaaccuuc      660

aaaguucugg accucaaaaa cuacauagac aaacagcuuc uccccauccu caacaaacaa      720

uccuguagca ucuccaacau cgaaaccguc auagaauuuc aacagaaaaa caacagacug      780

cucgaaauca cccgcgaguu cuccgucaac gccggcguca cgacucccgu cuccaccuau      840

augcucacga acucggaacu ccuuucccua aucaacgaca ugccgaucac caacgaccaa      900

aagaaacuca ugucaaacaa cguacaaauu guccgccaac aaucauacuc caucaugugc      960

auaauuaaag aagaaguccu cgcauacgua guccaacucc cccucuacgg cgucaucgac     1020

acccccugcu ggaaacucca caccucccca cucugcacaa ccaacaccaa agaaggcuca     1080

aacauaugcc uaacgcgcac cgaucgcggu ugguacugcg acaacgccgg uuccgucagc     1140

uucuuccccc aagcagagac augcaaaguc caaucaaacc gcgucuucug cgacaccaug     1200

aacucacuaa cccuuccaag cgaagucaac cucugcaacg uugacaucuu caaccccaaa     1260

uacgacugua aaaucaugac cuccaagacc gacguauccu cuuccgucau cacaucccua     1320

ggcgcuaucg uauccugcua ugguaaaacc aaaugcaccg ccuccaacaa aaaccgcggc     1380

aucaucaaga cauuuuccaa cggcugcgac uacgugagca acaaaggcgu cgacaccguc     1440

uccguaggca acacccucua cuauguaaac aaacaagagg gcaaaucacu cuacgucaaa     1500

ggggaaccca ucaucaacuu cuacgacccg cucguauucc ccagcgauga guucgacgcc     1560

uccaucuccc aggucaacga aaagauaaac caaucacucg cauucauucg uaaauccgac     1620

gaacuccuac acaacgugaa ugcaggcaaa ucgaccacua acaucaugau caccaccauc     1680

aucaucguca ucauagucau ccuccugucc cuuaucgccg ucggucuuuu auuauacugc     1740

aaagcccgca gcacccccgu cacccucucu aaggaccaac ucagcggcau caauaacauc     1800

gcauucucua acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1860

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1920

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1980

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     2040

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     2100

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     2160

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2280

ccaaaggcuc uuuucagagc caccagaauu                                      2310


<210>  1123
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1123
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccgga gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc     1800

gcguucucca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1124
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1124
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu ccacgcccgu gacccugagc aaggaccagc ucuccggcau caacaacauc     1800

gccuucagca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1125
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1125
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc     1800

gccuucucca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1126
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1126
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu cuacacccgu gacgcucagc aaggaccagc uguccgggau aaacaauauc     1800

gcuuuuucaa acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1127
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1127
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagaa gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc     1800

gccuucagca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1128
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1128
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu ccacccccgu gacgcuuagc aaggaccagc ugucuggaau uaacaauauc     1800

gcuuuuucca acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1129
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1129
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuau uaauccucaa agcgaacgcu      120

auuacuacca uucuaacagc agucacauuc ugcuucgccu caggccaaaa cauuacagaa      180

gaauuuuacc aaucaacaug cucugccgua ucaaaaggcu accuauccgc ccuacgaaca      240

ggcugguaca caagcguaau aacaaucgaa cuaucaaaca uaaaagaaaa caaaugcaac      300

gguacagacg ccaaaguuaa acuaauaaaa caagaacucg auaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaucaaca ccugcaacaa acaauagagc caggagagaa      420

uuaccucgau ucaugaauua cacacucaau aacgcaaaaa aaaccaacgu uacacuauca      480

aaaaaaagaa aacgacgauu cuuaggauuc cuacucggag ucggaucagc aauagcaucu      540

ggcguugcag uaugcaaagu auuacacuua gaaggugaag ucaauaaaau aaaaagcgcg      600

cuacuaagua caaacaaagc agucgucucc cuaucaaacg gagucucagu ccuaacauuc      660

aaaguacucg accuaaaaaa uuacauagau aaacaacuac uuccaauauu aaacaaacaa      720

uccuguagca ucagcaauau agaaacagua auagaauuuc aacaaaaaaa caaccgauua      780

uuagaaauca cucgagaauu uuccguaaac gccgggguaa caacuccagu cucaaccuac      840

augcuaacca auucagaacu auugagcuua auaaacgaca ugccaauaac caacgaccaa      900

aaaaaacuaa ugucuaacaa uguucaaauc gucagacaac aaaguuacag uauaaugugu      960

auaaucaaag aagaaguccu agcauacgua guccaacucc cacuauaugg aguuaucgac     1020

acaccauguu ggaaauuaca caccucacca uuaugcacaa ccaauacaaa agaaggauca     1080

aacauaugcc uuacacggac agaccgcgga ugguauugug acaacgcugg cucagucucc     1140

uuuuucccac aagcagaaac augcaaagua caaucaaaca gagucuuuug cgauaccaug     1200

aacucacuua cauuaccaag cgaaguaaau cuuuguaacg ucgacaucuu caauccuaaa     1260

uaugacugca aaaucaugac cucaaaaaca gacguuagcu cuucaguaau cacuagcuua     1320

ggagcaaucg uaucaugcua cggcaaaaca aaauguacag caucaaauaa aaacagagga     1380

aucauaaaaa cauuuucaaa cggaugcgau uauguaagca acaaaggagu agauacugua     1440

agcguaggaa acacauugua cuauguaaac aaacaagaag gaaaaucacu cuauguaaaa     1500

ggagaaccua uaaucaauuu cuacgaucca uuaguguucc caucagauga auuugacgcc     1560

ucaauaucac aaguuaauga aaaaauaaau caaucgcuag cauucauacg uaaaucagau     1620

gaauuacuac auaacguaaa cgcaggcaaa uccacaacaa auaucaugau cacaacaauu     1680

auaauaguaa uaauaguaau acuacuauca cuaauagccg uaggacuccu acuauacugc     1740

aaagcaagau cuacuccagu aacccucuca aaagaucaac uaagcggaau uaauaacauc     1800

gcauucagca acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1130
<211>  2090
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1130
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uuauccucaa agccaacgcc      120

aucaccacca uccucacagc aguaaccuuu ugcuucgccu caggccaaaa uaucacagaa      180

gaauuuuacc agaguaccug cuccgccgua uccaaaggau accucagcgc gcuccgcacc      240

ggcugguaca cuucaguaau cacaaucgaa cuauccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg cgaaagucaa acucaucaaa caagaacuag acaaauacaa aaaugccgua      360

acagaacuac aacuguuaau gcagagcaca cccgccacca acaaccgcgc ccgccgggaa      420

cucccccgau ucaugaacua cacacucaac aacgccaaaa agacgaacgu cacccucagc      480

aagaaacgaa aacgcagauu ccucgguuuc cuacuaggcg uaggcucagc aauagccucc      540

ggaguagccg ucugcaaagu ccugcacuua gaaggcgaag ucaacaaaau caaauccgcc      600

cuacucucca cgaacaaagc cgucgucucc cuguccaacg gugucuccgu uuuaaccuuc      660

aaaguucugg accucaaaaa cuacauagac aaacagcuuc uccccauccu caacaaacaa      720

uccuguagca ucuccaacau cgaaaccguc auagaauuuc aacagaaaaa caacagacug      780

cucgaaauca cccgcgaguu cuccgucaac gccggcguca cgacucccgu cuccaccuau      840

augcucacga acucggaacu ccuuucccua aucaacgaca ugccgaucac caacgaccaa      900

aagaaacuca ugucaaacaa cguacaaauu guccgccaac aaucauacuc caucaugugc      960

auaauuaaag aagaaguccu cgcauacgua guccaacucc cccucuacgg cgucaucgac     1020

acccccugcu ggaaacucca caccucccca cucugcacaa ccaacaccaa agaaggcuca     1080

aacauaugcc uaacgcgcac cgaucgcggu ugguacugcg acaacgccgg uuccgucagc     1140

uucuuccccc aagcagagac augcaaaguc caaucaaacc gcgucuucug cgacaccaug     1200

aacucacuaa cccuuccaag cgaagucaac cucugcaacg uugacaucuu caaccccaaa     1260

uacgacugua aaaucaugac cuccaagacc gacguauccu cuuccgucau cacaucccua     1320

ggcgcuaucg uauccugcua ugguaaaacc aaaugcaccg ccuccaacaa aaaccgcggc     1380

aucaucaaga cauuuuccaa cggcugcgac uacgugagca acaaaggcgu cgacaccguc     1440

uccguaggca acacccucua cuauguaaac aaacaagagg gcaaaucacu cuacgucaaa     1500

ggggaaccca ucaucaacuu cuacgacccg cucguauucc ccagcgauga guucgacgcc     1560

uccaucuccc aggucaacga aaagauaaac caaucacucg cauucauucg uaaauccgac     1620

gaacuccuac acaacgugaa ugcaggcaaa ucgaccacua acaucaugau caccaccauc     1680

aucaucguca ucauagucau ccuccugucc cuuaucgccg ucggucuuuu auuauacugc     1740

aaagcccgca gcacccccgu cacccucucu aaggaccaac ucagcggcau caauaacauc     1800

gcauucucua acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1860

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1920

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2040

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2090


<210>  1131
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1131
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1132
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1132
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcucca     1740

cgcccgugac ccugagcaag gaccagcucu ccggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1133
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1133
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1134
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1134
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggucua     1740

cacccgugac gcucagcaag gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1135
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1135
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1136
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1136
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggucca     1740

cccccgugac gcuuagcaag gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu     1800

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1137
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1137
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc      120

uaacagcagu cacauucugc uucgccucag gccaaaacau uacagaagaa uuuuaccaau      180

caacaugcuc ugccguauca aaaggcuacc uauccgcccu acgaacaggc ugguacacaa      240

gcguaauaac aaucgaacua ucaaacauaa aagaaaacaa augcaacggu acagacgcca      300

aaguuaaacu aauaaaacaa gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aucaacaccu gcaacaaaca auagagccag gagagaauua ccucgauuca      420

ugaauuacac acucaauaac gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac      480

gacgauucuu aggauuccua cucggagucg gaucagcaau agcaucuggc guugcaguau      540

gcaaaguauu acacuuagaa ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa      600

acaaagcagu cgucucccua ucaaacggag ucucaguccu aacauucaaa guacucgacc      660

uaaaaaauua cauagauaaa caacuacuuc caauauuaaa caaacaaucc uguagcauca      720

gcaauauaga aacaguaaua gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc      780

gagaauuuuc cguaaacgcc gggguaacaa cuccagucuc aaccuacaug cuaaccaauu      840

cagaacuauu gagcuuaaua aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu      900

cuaacaaugu ucaaaucguc agacaacaaa guuacaguau aauguguaua aucaaagaag      960

aaguccuagc auacguaguc caacucccac uauauggagu uaucgacaca ccauguugga     1020

aauuacacac cucaccauua ugcacaacca auacaaaaga aggaucaaac auaugccuua     1080

cacggacaga ccgcggaugg uauugugaca acgcuggcuc agucuccuuu uucccacaag     1140

cagaaacaug caaaguacaa ucaaacagag ucuuuugcga uaccaugaac ucacuuacau     1200

uaccaagcga aguaaaucuu uguaacgucg acaucuucaa uccuaaauau gacugcaaaa     1260

ucaugaccuc aaaaacagac guuagcucuu caguaaucac uagcuuagga gcaaucguau     1320

caugcuacgg caaaacaaaa uguacagcau caaauaaaaa cagaggaauc auaaaaacau     1380

uuucaaacgg augcgauuau guaagcaaca aaggaguaga uacuguaagc guaggaaaca     1440

cauuguacua uguaaacaaa caagaaggaa aaucacucua uguaaaagga gaaccuauaa     1500

ucaauuucua cgauccauua guguucccau cagaugaauu ugacgccuca auaucacaag     1560

uuaaugaaaa aauaaaucaa ucgcuagcau ucauacguaa aucagaugaa uuacuacaua     1620

acguaaacgc aggcaaaucc acaacaaaua ucaugaucac aacaauuaua auaguaauaa     1680

uaguaauacu acuaucacua auagccguag gacuccuacu auacugcaaa gcaagaucua     1740

cuccaguaac ccucucaaaa gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu     1800

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1138
<211>  2081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1138
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuua uccucaaagc caacgccauc accaccaucc      120

ucacagcagu aaccuuuugc uucgccucag gccaaaauau cacagaagaa uuuuaccaga      180

guaccugcuc cgccguaucc aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu      240

caguaaucac aaucgaacua uccaacauca aagaaaacaa augcaacggc accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa ugccguaaca gaacuacaac      360

uguuaaugca gagcacaccc gccaccaaca accgcgcccg ccgggaacuc ccccgauuca      420

ugaacuacac acucaacaac gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac      480

gcagauuccu cgguuuccua cuaggcguag gcucagcaau agccuccgga guagccgucu      540

gcaaaguccu gcacuuagaa ggcgaaguca acaaaaucaa auccgcccua cucuccacga      600

acaaagccgu cgucucccug uccaacggug ucuccguuuu aaccuucaaa guucuggacc      660

ucaaaaacua cauagacaaa cagcuucucc ccauccucaa caaacaaucc uguagcaucu      720

ccaacaucga aaccgucaua gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacga cucccgucuc caccuauaug cucacgaacu      840

cggaacuccu uucccuaauc aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu      900

caaacaacgu acaaauuguc cgccaacaau cauacuccau caugugcaua auuaaagaag      960

aaguccucgc auacguaguc caacuccccc ucuacggcgu caucgacacc cccugcugga     1020

aacuccacac cuccccacuc ugcacaacca acaccaaaga aggcucaaac auaugccuaa     1080

cgcgcaccga ucgcgguugg uacugcgaca acgccgguuc cgucagcuuc uucccccaag     1140

cagagacaug caaaguccaa ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc     1200

uuccaagcga agucaaccuc ugcaacguug acaucuucaa ccccaaauac gacuguaaaa     1260

ucaugaccuc caagaccgac guauccucuu ccgucaucac aucccuaggc gcuaucguau     1320

ccugcuaugg uaaaaccaaa ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau     1380

uuuccaacgg cugcgacuac gugagcaaca aaggcgucga caccgucucc guaggcaaca     1440

cccucuacua uguaaacaaa caagagggca aaucacucua cgucaaaggg gaacccauca     1500

ucaacuucua cgacccgcuc guauucccca gcgaugaguu cgacgccucc aucucccagg     1560

ucaacgaaaa gauaaaccaa ucacucgcau ucauucguaa auccgacgaa cuccuacaca     1620

acgugaaugc aggcaaaucg accacuaaca ucaugaucac caccaucauc aucgucauca     1680

uagucauccu ccugucccuu aucgccgucg gucuuuuauu auacugcaaa gcccgcagca     1740

cccccgucac ccucucuaag gaccaacuca gcggcaucaa uaacaucgca uucucuaacu     1800

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1860

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1920

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     2040

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2081


<210>  1139
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1139
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggagca     1740

cgcccgucac ccuguccaag gaccagcuga gcggcaucaa caacaucgcg uucuccaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1140
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1140
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcucca     1740

cgcccgugac ccugagcaag gaccagcucu ccggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1141
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1141
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcucca     1740

cccccgucac ccucuccaag gaccagcucu ccggcaucaa caacaucgcc uucuccaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1142
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1142
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggucua     1740

cacccgugac gcucagcaag gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1143
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaagca     1740

cccccgugac ccugagcaag gaccagcuga gcggcaucaa caacaucgcc uucagcaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1144
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggucca     1740

cccccgugac gcuuagcaag gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu     1800

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1145
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1145
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc      120

uaacagcagu cacauucugc uucgccucag gccaaaacau uacagaagaa uuuuaccaau      180

caacaugcuc ugccguauca aaaggcuacc uauccgcccu acgaacaggc ugguacacaa      240

gcguaauaac aaucgaacua ucaaacauaa aagaaaacaa augcaacggu acagacgcca      300

aaguuaaacu aauaaaacaa gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aucaacaccu gcaacaaaca auagagccag gagagaauua ccucgauuca      420

ugaauuacac acucaauaac gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac      480

gacgauucuu aggauuccua cucggagucg gaucagcaau agcaucuggc guugcaguau      540

gcaaaguauu acacuuagaa ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa      600

acaaagcagu cgucucccua ucaaacggag ucucaguccu aacauucaaa guacucgacc      660

uaaaaaauua cauagauaaa caacuacuuc caauauuaaa caaacaaucc uguagcauca      720

gcaauauaga aacaguaaua gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc      780

gagaauuuuc cguaaacgcc gggguaacaa cuccagucuc aaccuacaug cuaaccaauu      840

cagaacuauu gagcuuaaua aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu      900

cuaacaaugu ucaaaucguc agacaacaaa guuacaguau aauguguaua aucaaagaag      960

aaguccuagc auacguaguc caacucccac uauauggagu uaucgacaca ccauguugga     1020

aauuacacac cucaccauua ugcacaacca auacaaaaga aggaucaaac auaugccuua     1080

cacggacaga ccgcggaugg uauugugaca acgcuggcuc agucuccuuu uucccacaag     1140

cagaaacaug caaaguacaa ucaaacagag ucuuuugcga uaccaugaac ucacuuacau     1200

uaccaagcga aguaaaucuu uguaacgucg acaucuucaa uccuaaauau gacugcaaaa     1260

ucaugaccuc aaaaacagac guuagcucuu caguaaucac uagcuuagga gcaaucguau     1320

caugcuacgg caaaacaaaa uguacagcau caaauaaaaa cagaggaauc auaaaaacau     1380

uuucaaacgg augcgauuau guaagcaaca aaggaguaga uacuguaagc guaggaaaca     1440

cauuguacua uguaaacaaa caagaaggaa aaucacucua uguaaaagga gaaccuauaa     1500

ucaauuucua cgauccauua guguucccau cagaugaauu ugacgccuca auaucacaag     1560

uuaaugaaaa aauaaaucaa ucgcuagcau ucauacguaa aucagaugaa uuacuacaua     1620

acguaaacgc aggcaaaucc acaacaaaua ucaugaucac aacaauuaua auaguaauaa     1680

uaguaauacu acuaucacua auagccguag gacuccuacu auacugcaaa gcaagaucua     1740

cuccaguaac ccucucaaaa gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu     1800

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1146
<211>  2297
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1146
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuua uccucaaagc caacgccauc accaccaucc      120

ucacagcagu aaccuuuugc uucgccucag gccaaaauau cacagaagaa uuuuaccaga      180

guaccugcuc cgccguaucc aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu      240

caguaaucac aaucgaacua uccaacauca aagaaaacaa augcaacggc accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa ugccguaaca gaacuacaac      360

uguuaaugca gagcacaccc gccaccaaca accgcgcccg ccgggaacuc ccccgauuca      420

ugaacuacac acucaacaac gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac      480

gcagauuccu cgguuuccua cuaggcguag gcucagcaau agccuccgga guagccgucu      540

gcaaaguccu gcacuuagaa ggcgaaguca acaaaaucaa auccgcccua cucuccacga      600

acaaagccgu cgucucccug uccaacggug ucuccguuuu aaccuucaaa guucuggacc      660

ucaaaaacua cauagacaaa cagcuucucc ccauccucaa caaacaaucc uguagcaucu      720

ccaacaucga aaccgucaua gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacga cucccgucuc caccuauaug cucacgaacu      840

cggaacuccu uucccuaauc aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu      900

caaacaacgu acaaauuguc cgccaacaau cauacuccau caugugcaua auuaaagaag      960

aaguccucgc auacguaguc caacuccccc ucuacggcgu caucgacacc cccugcugga     1020

aacuccacac cuccccacuc ugcacaacca acaccaaaga aggcucaaac auaugccuaa     1080

cgcgcaccga ucgcgguugg uacugcgaca acgccgguuc cgucagcuuc uucccccaag     1140

cagagacaug caaaguccaa ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc     1200

uuccaagcga agucaaccuc ugcaacguug acaucuucaa ccccaaauac gacuguaaaa     1260

ucaugaccuc caagaccgac guauccucuu ccgucaucac aucccuaggc gcuaucguau     1320

ccugcuaugg uaaaaccaaa ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau     1380

uuuccaacgg cugcgacuac gugagcaaca aaggcgucga caccgucucc guaggcaaca     1440

cccucuacua uguaaacaaa caagagggca aaucacucua cgucaaaggg gaacccauca     1500

ucaacuucua cgacccgcuc guauucccca gcgaugaguu cgacgccucc aucucccagg     1560

ucaacgaaaa gauaaaccaa ucacucgcau ucauucguaa auccgacgaa cuccuacaca     1620

acgugaaugc aggcaaaucg accacuaaca ucaugaucac caccaucauc aucgucauca     1680

uagucauccu ccugucccuu aucgccgucg gucuuuuauu auacugcaaa gcccgcagca     1740

cccccgucac ccucucuaag gaccaacuca gcggcaucaa uaacaucgca uucucuaacu     1800

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1860

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1920

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1980

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     2040

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     2100

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     2160

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2280

ucagagccac cagaauu                                                    2297


<210>  1147
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1147
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1148
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1148
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcuc cacgcccgug     1740

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1149
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1149
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1150
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1150
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccagguc uacacccgug     1740

acgcucagca aggaccagcu guccgggaua aacaauaucg cuuuuucaaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1151
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1151
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1152
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1152
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccgguc cacccccgug     1740

acgcuuagca aggaccagcu gucuggaauu aacaauaucg cuuuuuccaa cugaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1153
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1153
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuauu aauccucaaa gcgaacgcua uuacuaccau ucuaacagca      120

gucacauucu gcuucgccuc aggccaaaac auuacagaag aauuuuacca aucaacaugc      180

ucugccguau caaaaggcua ccuauccgcc cuacgaacag gcugguacac aagcguaaua      240

acaaucgaac uaucaaacau aaaagaaaac aaaugcaacg guacagacgc caaaguuaaa      300

cuaauaaaac aagaacucga uaaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaucaacac cugcaacaaa caauagagcc aggagagaau uaccucgauu caugaauuac      420

acacucaaua acgcaaaaaa aaccaacguu acacuaucaa aaaaaagaaa acgacgauuc      480

uuaggauucc uacucggagu cggaucagca auagcaucug gcguugcagu augcaaagua      540

uuacacuuag aaggugaagu caauaaaaua aaaagcgcgc uacuaaguac aaacaaagca      600

gucgucuccc uaucaaacgg agucucaguc cuaacauuca aaguacucga ccuaaaaaau      660

uacauagaua aacaacuacu uccaauauua aacaaacaau ccuguagcau cagcaauaua      720

gaaacaguaa uagaauuuca acaaaaaaac aaccgauuau uagaaaucac ucgagaauuu      780

uccguaaacg ccgggguaac aacuccaguc ucaaccuaca ugcuaaccaa uucagaacua      840

uugagcuuaa uaaacgacau gccaauaacc aacgaccaaa aaaaacuaau gucuaacaau      900

guucaaaucg ucagacaaca aaguuacagu auaaugugua uaaucaaaga agaaguccua      960

gcauacguag uccaacuccc acuauaugga guuaucgaca caccauguug gaaauuacac     1020

accucaccau uaugcacaac caauacaaaa gaaggaucaa acauaugccu uacacggaca     1080

gaccgcggau gguauuguga caacgcuggc ucagucuccu uuuucccaca agcagaaaca     1140

ugcaaaguac aaucaaacag agucuuuugc gauaccauga acucacuuac auuaccaagc     1200

gaaguaaauc uuuguaacgu cgacaucuuc aauccuaaau augacugcaa aaucaugacc     1260

ucaaaaacag acguuagcuc uucaguaauc acuagcuuag gagcaaucgu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaauaaa aacagaggaa ucauaaaaac auuuucaaac     1380

ggaugcgauu auguaagcaa caaaggagua gauacuguaa gcguaggaaa cacauuguac     1440

uauguaaaca aacaagaagg aaaaucacuc uauguaaaag gagaaccuau aaucaauuuc     1500

uacgauccau uaguguuccc aucagaugaa uuugacgccu caauaucaca aguuaaugaa     1560

aaaauaaauc aaucgcuagc auucauacgu aaaucagaug aauuacuaca uaacguaaac     1620

gcaggcaaau ccacaacaaa uaucaugauc acaacaauua uaauaguaau aauaguaaua     1680

cuacuaucac uaauagccgu aggacuccua cuauacugca aagcaagauc uacuccagua     1740

acccucucaa aagaucaacu aagcggaauu aauaacaucg cauucagcaa cuaaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1154
<211>  2073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1154
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu uauccucaaa gccaacgcca ucaccaccau ccucacagca      120

guaaccuuuu gcuucgccuc aggccaaaau aucacagaag aauuuuacca gaguaccugc      180

uccgccguau ccaaaggaua ccucagcgcg cuccgcaccg gcugguacac uucaguaauc      240

acaaucgaac uauccaacau caaagaaaac aaaugcaacg gcaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aaugccguaa cagaacuaca acuguuaaug      360

cagagcacac ccgccaccaa caaccgcgcc cgccgggaac ucccccgauu caugaacuac      420

acacucaaca acgccaaaaa gacgaacguc acccucagca agaaacgaaa acgcagauuc      480

cucgguuucc uacuaggcgu aggcucagca auagccuccg gaguagccgu cugcaaaguc      540

cugcacuuag aaggcgaagu caacaaaauc aaauccgccc uacucuccac gaacaaagcc      600

gucgucuccc uguccaacgg ugucuccguu uuaaccuuca aaguucugga ccucaaaaac      660

uacauagaca aacagcuucu ccccauccuc aacaaacaau ccuguagcau cuccaacauc      720

gaaaccguca uagaauuuca acagaaaaac aacagacugc ucgaaaucac ccgcgaguuc      780

uccgucaacg ccggcgucac gacucccguc uccaccuaua ugcucacgaa cucggaacuc      840

cuuucccuaa ucaacgacau gccgaucacc aacgaccaaa agaaacucau gucaaacaac      900

guacaaauug uccgccaaca aucauacucc aucaugugca uaauuaaaga agaaguccuc      960

gcauacguag uccaacuccc ccucuacggc gucaucgaca cccccugcug gaaacuccac     1020

accuccccac ucugcacaac caacaccaaa gaaggcucaa acauaugccu aacgcgcacc     1080

gaucgcgguu gguacugcga caacgccggu uccgucagcu ucuuccccca agcagagaca     1140

ugcaaagucc aaucaaaccg cgucuucugc gacaccauga acucacuaac ccuuccaagc     1200

gaagucaacc ucugcaacgu ugacaucuuc aaccccaaau acgacuguaa aaucaugacc     1260

uccaagaccg acguauccuc uuccgucauc acaucccuag gcgcuaucgu auccugcuau     1320

gguaaaacca aaugcaccgc cuccaacaaa aaccgcggca ucaucaagac auuuuccaac     1380

ggcugcgacu acgugagcaa caaaggcguc gacaccgucu ccguaggcaa cacccucuac     1440

uauguaaaca aacaagaggg caaaucacuc uacgucaaag gggaacccau caucaacuuc     1500

uacgacccgc ucguauuccc cagcgaugag uucgacgccu ccaucuccca ggucaacgaa     1560

aagauaaacc aaucacucgc auucauucgu aaauccgacg aacuccuaca caacgugaau     1620

gcaggcaaau cgaccacuaa caucaugauc accaccauca ucaucgucau cauagucauc     1680

cuccuguccc uuaucgccgu cggucuuuua uuauacugca aagcccgcag cacccccguc     1740

acccucucua aggaccaacu cagcggcauc aauaacaucg cauucucuaa cuaaggacua     1800

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1860

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1920

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2040

cccccaaagg cucuuuucag agccaccaga auu                                  2073


<210>  1155
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1155
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1740

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1156
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1156
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcuc cacgcccgug     1740

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1157
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1157
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1740

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1158
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1158
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccagguc uacacccgug     1740

acgcucagca aggaccagcu guccgggaua aacaauaucg cuuuuucaaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1159
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1159
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1740

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1160
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1160
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccgguc cacccccgug     1740

acgcuuagca aggaccagcu gucuggaauu aacaauaucg cuuuuuccaa cugaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1161
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1161
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuauu aauccucaaa gcgaacgcua uuacuaccau ucuaacagca      120

gucacauucu gcuucgccuc aggccaaaac auuacagaag aauuuuacca aucaacaugc      180

ucugccguau caaaaggcua ccuauccgcc cuacgaacag gcugguacac aagcguaaua      240

acaaucgaac uaucaaacau aaaagaaaac aaaugcaacg guacagacgc caaaguuaaa      300

cuaauaaaac aagaacucga uaaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaucaacac cugcaacaaa caauagagcc aggagagaau uaccucgauu caugaauuac      420

acacucaaua acgcaaaaaa aaccaacguu acacuaucaa aaaaaagaaa acgacgauuc      480

uuaggauucc uacucggagu cggaucagca auagcaucug gcguugcagu augcaaagua      540

uuacacuuag aaggugaagu caauaaaaua aaaagcgcgc uacuaaguac aaacaaagca      600

gucgucuccc uaucaaacgg agucucaguc cuaacauuca aaguacucga ccuaaaaaau      660

uacauagaua aacaacuacu uccaauauua aacaaacaau ccuguagcau cagcaauaua      720

gaaacaguaa uagaauuuca acaaaaaaac aaccgauuau uagaaaucac ucgagaauuu      780

uccguaaacg ccgggguaac aacuccaguc ucaaccuaca ugcuaaccaa uucagaacua      840

uugagcuuaa uaaacgacau gccaauaacc aacgaccaaa aaaaacuaau gucuaacaau      900

guucaaaucg ucagacaaca aaguuacagu auaaugugua uaaucaaaga agaaguccua      960

gcauacguag uccaacuccc acuauaugga guuaucgaca caccauguug gaaauuacac     1020

accucaccau uaugcacaac caauacaaaa gaaggaucaa acauaugccu uacacggaca     1080

gaccgcggau gguauuguga caacgcuggc ucagucuccu uuuucccaca agcagaaaca     1140

ugcaaaguac aaucaaacag agucuuuugc gauaccauga acucacuuac auuaccaagc     1200

gaaguaaauc uuuguaacgu cgacaucuuc aauccuaaau augacugcaa aaucaugacc     1260

ucaaaaacag acguuagcuc uucaguaauc acuagcuuag gagcaaucgu aucaugcuac     1320

ggcaaaacaa aauguacagc aucaaauaaa aacagaggaa ucauaaaaac auuuucaaac     1380

ggaugcgauu auguaagcaa caaaggagua gauacuguaa gcguaggaaa cacauuguac     1440

uauguaaaca aacaagaagg aaaaucacuc uauguaaaag gagaaccuau aaucaauuuc     1500

uacgauccau uaguguuccc aucagaugaa uuugacgccu caauaucaca aguuaaugaa     1560

aaaauaaauc aaucgcuagc auucauacgu aaaucagaug aauuacuaca uaacguaaac     1620

gcaggcaaau ccacaacaaa uaucaugauc acaacaauua uaauaguaau aauaguaaua     1680

cuacuaucac uaauagccgu aggacuccua cuauacugca aagcaagauc uacuccagua     1740

acccucucaa aagaucaacu aagcggaauu aauaacaucg cauucagcaa cuaaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1162
<211>  2069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1162
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu uauccucaaa gccaacgcca ucaccaccau ccucacagca      120

guaaccuuuu gcuucgccuc aggccaaaau aucacagaag aauuuuacca gaguaccugc      180

uccgccguau ccaaaggaua ccucagcgcg cuccgcaccg gcugguacac uucaguaauc      240

acaaucgaac uauccaacau caaagaaaac aaaugcaacg gcaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aaugccguaa cagaacuaca acuguuaaug      360

cagagcacac ccgccaccaa caaccgcgcc cgccgggaac ucccccgauu caugaacuac      420

acacucaaca acgccaaaaa gacgaacguc acccucagca agaaacgaaa acgcagauuc      480

cucgguuucc uacuaggcgu aggcucagca auagccuccg gaguagccgu cugcaaaguc      540

cugcacuuag aaggcgaagu caacaaaauc aaauccgccc uacucuccac gaacaaagcc      600

gucgucuccc uguccaacgg ugucuccguu uuaaccuuca aaguucugga ccucaaaaac      660

uacauagaca aacagcuucu ccccauccuc aacaaacaau ccuguagcau cuccaacauc      720

gaaaccguca uagaauuuca acagaaaaac aacagacugc ucgaaaucac ccgcgaguuc      780

uccgucaacg ccggcgucac gacucccguc uccaccuaua ugcucacgaa cucggaacuc      840

cuuucccuaa ucaacgacau gccgaucacc aacgaccaaa agaaacucau gucaaacaac      900

guacaaauug uccgccaaca aucauacucc aucaugugca uaauuaaaga agaaguccuc      960

gcauacguag uccaacuccc ccucuacggc gucaucgaca cccccugcug gaaacuccac     1020

accuccccac ucugcacaac caacaccaaa gaaggcucaa acauaugccu aacgcgcacc     1080

gaucgcgguu gguacugcga caacgccggu uccgucagcu ucuuccccca agcagagaca     1140

ugcaaagucc aaucaaaccg cgucuucugc gacaccauga acucacuaac ccuuccaagc     1200

gaagucaacc ucugcaacgu ugacaucuuc aaccccaaau acgacuguaa aaucaugacc     1260

uccaagaccg acguauccuc uuccgucauc acaucccuag gcgcuaucgu auccugcuau     1320

gguaaaacca aaugcaccgc cuccaacaaa aaccgcggca ucaucaagac auuuuccaac     1380

ggcugcgacu acgugagcaa caaaggcguc gacaccgucu ccguaggcaa cacccucuac     1440

uauguaaaca aacaagaggg caaaucacuc uacgucaaag gggaacccau caucaacuuc     1500

uacgacccgc ucguauuccc cagcgaugag uucgacgccu ccaucuccca ggucaacgaa     1560

aagauaaacc aaucacucgc auucauucgu aaauccgacg aacuccuaca caacgugaau     1620

gcaggcaaau cgaccacuaa caucaugauc accaccauca ucaucgucau cauagucauc     1680

cuccuguccc uuaucgccgu cggucuuuua uuauacugca aagcccgcag cacccccguc     1740

acccucucua aggaccaacu cagcggcauc aauaacaucg cauucucuaa cuaaggacua     1800

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1860

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1920

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     2040

caaaggcucu uuucagagcc accagaauu                                       2069


<210>  1163
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1163
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1164
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1164
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcuccac gcccgugacc cugagcaagg accagcucuc cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1165
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1165
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1166
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1166
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggucuac acccgugacg cucagcaagg accagcuguc cgggauaaac     1800

aauaucgcuu uuucaaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1167
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1167
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1168
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1168
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccgguccac ccccgugacg cuuagcaagg accagcuguc uggaauuaac     1800

aauaucgcuu uuuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1169
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1169
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuauuaau ccucaaagcg      120

aacgcuauua cuaccauucu aacagcaguc acauucugcu ucgccucagg ccaaaacauu      180

acagaagaau uuuaccaauc aacaugcucu gccguaucaa aaggcuaccu auccgcccua      240

cgaacaggcu gguacacaag cguaauaaca aucgaacuau caaacauaaa agaaaacaaa      300

ugcaacggua cagacgccaa aguuaaacua auaaaacaag aacucgauaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa ucaacaccug caacaaacaa uagagccagg      420

agagaauuac cucgauucau gaauuacaca cucaauaacg caaaaaaaac caacguuaca      480

cuaucaaaaa aaagaaaacg acgauucuua ggauuccuac ucggagucgg aucagcaaua      540

gcaucuggcg uugcaguaug caaaguauua cacuuagaag gugaagucaa uaaaauaaaa      600

agcgcgcuac uaaguacaaa caaagcaguc gucucccuau caaacggagu cucaguccua      660

acauucaaag uacucgaccu aaaaaauuac auagauaaac aacuacuucc aauauuaaac      720

aaacaauccu guagcaucag caauauagaa acaguaauag aauuucaaca aaaaaacaac      780

cgauuauuag aaaucacucg agaauuuucc guaaacgccg ggguaacaac uccagucuca      840

accuacaugc uaaccaauuc agaacuauug agcuuaauaa acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaauguc uaacaauguu caaaucguca gacaacaaag uuacaguaua      960

auguguauaa ucaaagaaga aguccuagca uacguagucc aacucccacu auauggaguu     1020

aucgacacac cauguuggaa auuacacacc ucaccauuau gcacaaccaa uacaaaagaa     1080

ggaucaaaca uaugccuuac acggacagac cgcggauggu auugugacaa cgcuggcuca     1140

gucuccuuuu ucccacaagc agaaacaugc aaaguacaau caaacagagu cuuuugcgau     1200

accaugaacu cacuuacauu accaagcgaa guaaaucuuu guaacgucga caucuucaau     1260

ccuaaauaug acugcaaaau caugaccuca aaaacagacg uuagcucuuc aguaaucacu     1320

agcuuaggag caaucguauc augcuacggc aaaacaaaau guacagcauc aaauaaaaac     1380

agaggaauca uaaaaacauu uucaaacgga ugcgauuaug uaagcaacaa aggaguagau     1440

acuguaagcg uaggaaacac auuguacuau guaaacaaac aagaaggaaa aucacucuau     1500

guaaaaggag aaccuauaau caauuucuac gauccauuag uguucccauc agaugaauuu     1560

gacgccucaa uaucacaagu uaaugaaaaa auaaaucaau cgcuagcauu cauacguaaa     1620

ucagaugaau uacuacauaa cguaaacgca ggcaaaucca caacaaauau caugaucaca     1680

acaauuauaa uaguaauaau aguaauacua cuaucacuaa uagccguagg acuccuacua     1740

uacugcaaag caagaucuac uccaguaacc cucucaaaag aucaacuaag cggaauuaau     1800

aacaucgcau ucagcaacua aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1170
<211>  2084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1170
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuuau ccucaaagcc      120

aacgccauca ccaccauccu cacagcagua accuuuugcu ucgccucagg ccaaaauauc      180

acagaagaau uuuaccagag uaccugcucc gccguaucca aaggauaccu cagcgcgcuc      240

cgcaccggcu gguacacuuc aguaaucaca aucgaacuau ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa auacaaaaau      360

gccguaacag aacuacaacu guuaaugcag agcacacccg ccaccaacaa ccgcgcccgc      420

cgggaacucc cccgauucau gaacuacaca cucaacaacg ccaaaaagac gaacgucacc      480

cucagcaaga aacgaaaacg cagauuccuc gguuuccuac uaggcguagg cucagcaaua      540

gccuccggag uagccgucug caaaguccug cacuuagaag gcgaagucaa caaaaucaaa      600

uccgcccuac ucuccacgaa caaagccguc gucucccugu ccaacggugu cuccguuuua      660

accuucaaag uucuggaccu caaaaacuac auagacaaac agcuucuccc cauccucaac      720

aaacaauccu guagcaucuc caacaucgaa accgucauag aauuucaaca gaaaaacaac      780

agacugcucg aaaucacccg cgaguucucc gucaacgccg gcgucacgac ucccgucucc      840

accuauaugc ucacgaacuc ggaacuccuu ucccuaauca acgacaugcc gaucaccaac      900

gaccaaaaga aacucauguc aaacaacgua caaauugucc gccaacaauc auacuccauc      960

augugcauaa uuaaagaaga aguccucgca uacguagucc aacucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa acuccacacc uccccacucu gcacaaccaa caccaaagaa     1080

ggcucaaaca uaugccuaac gcgcaccgau cgcgguuggu acugcgacaa cgccgguucc     1140

gucagcuucu ucccccaagc agagacaugc aaaguccaau caaaccgcgu cuucugcgac     1200

accaugaacu cacuaacccu uccaagcgaa gucaaccucu gcaacguuga caucuucaac     1260

cccaaauacg acuguaaaau caugaccucc aagaccgacg uauccucuuc cgucaucaca     1320

ucccuaggcg cuaucguauc cugcuauggu aaaaccaaau gcaccgccuc caacaaaaac     1380

cgcggcauca ucaagacauu uuccaacggc ugcgacuacg ugagcaacaa aggcgucgac     1440

accgucuccg uaggcaacac ccucuacuau guaaacaaac aagagggcaa aucacucuac     1500

gucaaagggg aacccaucau caacuucuac gacccgcucg uauuccccag cgaugaguuc     1560

gacgccucca ucucccaggu caacgaaaag auaaaccaau cacucgcauu cauucguaaa     1620

uccgacgaac uccuacacaa cgugaaugca ggcaaaucga ccacuaacau caugaucacc     1680

accaucauca ucgucaucau agucauccuc cugucccuua ucgccgucgg ucuuuuauua     1740

uacugcaaag cccgcagcac ccccgucacc cucucuaagg accaacucag cggcaucaau     1800

aacaucgcau ucucuaacua aggacuagua auaaggaaac uguaugaaug ucugugggca     1860

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1920

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     2040

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2084


<210>  1171
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1171
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1800

aacaucgcgu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1172
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1172
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcuccac gcccgugacc cugagcaagg accagcucuc cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1173
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1173
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1800

aacaucgccu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1174
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1174
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggucuac acccgugacg cucagcaagg accagcuguc cgggauaaac     1800

aauaucgcuu uuucaaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1175
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1175
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1800

aacaucgccu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1176
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1176
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccgguccac ccccgugacg cuuagcaagg accagcuguc uggaauuaac     1800

aauaucgcuu uuuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1177
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1177
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuauuaau ccucaaagcg      120

aacgcuauua cuaccauucu aacagcaguc acauucugcu ucgccucagg ccaaaacauu      180

acagaagaau uuuaccaauc aacaugcucu gccguaucaa aaggcuaccu auccgcccua      240

cgaacaggcu gguacacaag cguaauaaca aucgaacuau caaacauaaa agaaaacaaa      300

ugcaacggua cagacgccaa aguuaaacua auaaaacaag aacucgauaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa ucaacaccug caacaaacaa uagagccagg      420

agagaauuac cucgauucau gaauuacaca cucaauaacg caaaaaaaac caacguuaca      480

cuaucaaaaa aaagaaaacg acgauucuua ggauuccuac ucggagucgg aucagcaaua      540

gcaucuggcg uugcaguaug caaaguauua cacuuagaag gugaagucaa uaaaauaaaa      600

agcgcgcuac uaaguacaaa caaagcaguc gucucccuau caaacggagu cucaguccua      660

acauucaaag uacucgaccu aaaaaauuac auagauaaac aacuacuucc aauauuaaac      720

aaacaauccu guagcaucag caauauagaa acaguaauag aauuucaaca aaaaaacaac      780

cgauuauuag aaaucacucg agaauuuucc guaaacgccg ggguaacaac uccagucuca      840

accuacaugc uaaccaauuc agaacuauug agcuuaauaa acgacaugcc aauaaccaac      900

gaccaaaaaa aacuaauguc uaacaauguu caaaucguca gacaacaaag uuacaguaua      960

auguguauaa ucaaagaaga aguccuagca uacguagucc aacucccacu auauggaguu     1020

aucgacacac cauguuggaa auuacacacc ucaccauuau gcacaaccaa uacaaaagaa     1080

ggaucaaaca uaugccuuac acggacagac cgcggauggu auugugacaa cgcuggcuca     1140

gucuccuuuu ucccacaagc agaaacaugc aaaguacaau caaacagagu cuuuugcgau     1200

accaugaacu cacuuacauu accaagcgaa guaaaucuuu guaacgucga caucuucaau     1260

ccuaaauaug acugcaaaau caugaccuca aaaacagacg uuagcucuuc aguaaucacu     1320

agcuuaggag caaucguauc augcuacggc aaaacaaaau guacagcauc aaauaaaaac     1380

agaggaauca uaaaaacauu uucaaacgga ugcgauuaug uaagcaacaa aggaguagau     1440

acuguaagcg uaggaaacac auuguacuau guaaacaaac aagaaggaaa aucacucuau     1500

guaaaaggag aaccuauaau caauuucuac gauccauuag uguucccauc agaugaauuu     1560

gacgccucaa uaucacaagu uaaugaaaaa auaaaucaau cgcuagcauu cauacguaaa     1620

ucagaugaau uacuacauaa cguaaacgca ggcaaaucca caacaaauau caugaucaca     1680

acaauuauaa uaguaauaau aguaauacua cuaucacuaa uagccguagg acuccuacua     1740

uacugcaaag caagaucuac uccaguaacc cucucaaaag aucaacuaag cggaauuaau     1800

aacaucgcau ucagcaacua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1178
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1178
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuuau ccucaaagcc      120

aacgccauca ccaccauccu cacagcagua accuuuugcu ucgccucagg ccaaaauauc      180

acagaagaau uuuaccagag uaccugcucc gccguaucca aaggauaccu cagcgcgcuc      240

cgcaccggcu gguacacuuc aguaaucaca aucgaacuau ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa auacaaaaau      360

gccguaacag aacuacaacu guuaaugcag agcacacccg ccaccaacaa ccgcgcccgc      420

cgggaacucc cccgauucau gaacuacaca cucaacaacg ccaaaaagac gaacgucacc      480

cucagcaaga aacgaaaacg cagauuccuc gguuuccuac uaggcguagg cucagcaaua      540

gccuccggag uagccgucug caaaguccug cacuuagaag gcgaagucaa caaaaucaaa      600

uccgcccuac ucuccacgaa caaagccguc gucucccugu ccaacggugu cuccguuuua      660

accuucaaag uucuggaccu caaaaacuac auagacaaac agcuucuccc cauccucaac      720

aaacaauccu guagcaucuc caacaucgaa accgucauag aauuucaaca gaaaaacaac      780

agacugcucg aaaucacccg cgaguucucc gucaacgccg gcgucacgac ucccgucucc      840

accuauaugc ucacgaacuc ggaacuccuu ucccuaauca acgacaugcc gaucaccaac      900

gaccaaaaga aacucauguc aaacaacgua caaauugucc gccaacaauc auacuccauc      960

augugcauaa uuaaagaaga aguccucgca uacguagucc aacucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa acuccacacc uccccacucu gcacaaccaa caccaaagaa     1080

ggcucaaaca uaugccuaac gcgcaccgau cgcgguuggu acugcgacaa cgccgguucc     1140

gucagcuucu ucccccaagc agagacaugc aaaguccaau caaaccgcgu cuucugcgac     1200

accaugaacu cacuaacccu uccaagcgaa gucaaccucu gcaacguuga caucuucaac     1260

cccaaauacg acuguaaaau caugaccucc aagaccgacg uauccucuuc cgucaucaca     1320

ucccuaggcg cuaucguauc cugcuauggu aaaaccaaau gcaccgccuc caacaaaaac     1380

cgcggcauca ucaagacauu uuccaacggc ugcgacuacg ugagcaacaa aggcgucgac     1440

accgucuccg uaggcaacac ccucuacuau guaaacaaac aagagggcaa aucacucuac     1500

gucaaagggg aacccaucau caacuucuac gacccgcucg uauuccccag cgaugaguuc     1560

gacgccucca ucucccaggu caacgaaaag auaaaccaau cacucgcauu cauucguaaa     1620

uccgacgaac uccuacacaa cgugaaugca ggcaaaucga ccacuaacau caugaucacc     1680

accaucauca ucgucaucau agucauccuc cugucccuua ucgccgucgg ucuuuuauua     1740

uacugcaaag cccgcagcac ccccgucacc cucucuaagg accaacucag cggcaucaau     1800

aacaucgcau ucucuaacua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1860

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1920

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1980

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     2040

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2100

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2160

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  1179
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1179
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1180
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1180
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcuccacgcc cgugacccug     1800

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1181
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1181
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1182
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1182
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggucuacacc cgugacgcuc     1800

agcaaggacc agcuguccgg gauaaacaau aucgcuuuuu caaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1183
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1183
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1184
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1184
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc gguccacccc cgugacgcuu     1800

agcaaggacc agcugucugg aauuaacaau aucgcuuuuu ccaacugagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1185
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1185
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uauuaauccu caaagcgaac gcuauuacua ccauucuaac agcagucaca      180

uucugcuucg ccucaggcca aaacauuaca gaagaauuuu accaaucaac augcucugcc      240

guaucaaaag gcuaccuauc cgcccuacga acaggcuggu acacaagcgu aauaacaauc      300

gaacuaucaa acauaaaaga aaacaaaugc aacgguacag acgccaaagu uaaacuaaua      360

aaacaagaac ucgauaaaua caaaaacgca guaacagaau uacaacuacu aaugcaauca      420

acaccugcaa caaacaauag agccaggaga gaauuaccuc gauucaugaa uuacacacuc      480

aauaacgcaa aaaaaaccaa cguuacacua ucaaaaaaaa gaaaacgacg auucuuagga      540

uuccuacucg gagucggauc agcaauagca ucuggcguug caguaugcaa aguauuacac      600

uuagaaggug aagucaauaa aauaaaaagc gcgcuacuaa guacaaacaa agcagucguc      660

ucccuaucaa acggagucuc aguccuaaca uucaaaguac ucgaccuaaa aaauuacaua      720

gauaaacaac uacuuccaau auuaaacaaa caauccugua gcaucagcaa uauagaaaca      780

guaauagaau uucaacaaaa aaacaaccga uuauuagaaa ucacucgaga auuuuccgua      840

aacgccgggg uaacaacucc agucucaacc uacaugcuaa ccaauucaga acuauugagc      900

uuaauaaacg acaugccaau aaccaacgac caaaaaaaac uaaugucuaa caauguucaa      960

aucgucagac aacaaaguua caguauaaug uguauaauca aagaagaagu ccuagcauac     1020

guaguccaac ucccacuaua uggaguuauc gacacaccau guuggaaauu acacaccuca     1080

ccauuaugca caaccaauac aaaagaagga ucaaacauau gccuuacacg gacagaccgc     1140

ggaugguauu gugacaacgc uggcucaguc uccuuuuucc cacaagcaga aacaugcaaa     1200

guacaaucaa acagagucuu uugcgauacc augaacucac uuacauuacc aagcgaagua     1260

aaucuuugua acgucgacau cuucaauccu aaauaugacu gcaaaaucau gaccucaaaa     1320

acagacguua gcucuucagu aaucacuagc uuaggagcaa ucguaucaug cuacggcaaa     1380

acaaaaugua cagcaucaaa uaaaaacaga ggaaucauaa aaacauuuuc aaacggaugc     1440

gauuauguaa gcaacaaagg aguagauacu guaagcguag gaaacacauu guacuaugua     1500

aacaaacaag aaggaaaauc acucuaugua aaaggagaac cuauaaucaa uuucuacgau     1560

ccauuagugu ucccaucaga ugaauuugac gccucaauau cacaaguuaa ugaaaaaaua     1620

aaucaaucgc uagcauucau acguaaauca gaugaauuac uacauaacgu aaacgcaggc     1680

aaauccacaa caaauaucau gaucacaaca auuauaauag uaauaauagu aauacuacua     1740

ucacuaauag ccguaggacu ccuacuauac ugcaaagcaa gaucuacucc aguaacccuc     1800

ucaaaagauc aacuaagcgg aauuaauaac aucgcauuca gcaacuaagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1186
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1186
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuuauccu caaagccaac gccaucacca ccauccucac agcaguaacc      180

uuuugcuucg ccucaggcca aaauaucaca gaagaauuuu accagaguac cugcuccgcc      240

guauccaaag gauaccucag cgcgcuccgc accggcuggu acacuucagu aaucacaauc      300

gaacuaucca acaucaaaga aaacaaaugc aacggcaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaaugcc guaacagaac uacaacuguu aaugcagagc      420

acacccgcca ccaacaaccg cgcccgccgg gaacuccccc gauucaugaa cuacacacuc      480

aacaacgcca aaaagacgaa cgucacccuc agcaagaaac gaaaacgcag auuccucggu      540

uuccuacuag gcguaggcuc agcaauagcc uccggaguag ccgucugcaa aguccugcac      600

uuagaaggcg aagucaacaa aaucaaaucc gcccuacucu ccacgaacaa agccgucguc      660

ucccugucca acggugucuc cguuuuaacc uucaaaguuc uggaccucaa aaacuacaua      720

gacaaacagc uucuccccau ccucaacaaa caauccugua gcaucuccaa caucgaaacc      780

gucauagaau uucaacagaa aaacaacaga cugcucgaaa ucacccgcga guucuccguc      840

aacgccggcg ucacgacucc cgucuccacc uauaugcuca cgaacucgga acuccuuucc      900

cuaaucaacg acaugccgau caccaacgac caaaagaaac ucaugucaaa caacguacaa      960

auuguccgcc aacaaucaua cuccaucaug ugcauaauua aagaagaagu ccucgcauac     1020

guaguccaac ucccccucua cggcgucauc gacacccccu gcuggaaacu ccacaccucc     1080

ccacucugca caaccaacac caaagaaggc ucaaacauau gccuaacgcg caccgaucgc     1140

gguugguacu gcgacaacgc cgguuccguc agcuucuucc cccaagcaga gacaugcaaa     1200

guccaaucaa accgcgucuu cugcgacacc augaacucac uaacccuucc aagcgaaguc     1260

aaccucugca acguugacau cuucaacccc aaauacgacu guaaaaucau gaccuccaag     1320

accgacguau ccucuuccgu caucacaucc cuaggcgcua ucguauccug cuaugguaaa     1380

accaaaugca ccgccuccaa caaaaaccgc ggcaucauca agacauuuuc caacggcugc     1440

gacuacguga gcaacaaagg cgucgacacc gucuccguag gcaacacccu cuacuaugua     1500

aacaaacaag agggcaaauc acucuacguc aaaggggaac ccaucaucaa cuucuacgac     1560

ccgcucguau uccccagcga ugaguucgac gccuccaucu cccaggucaa cgaaaagaua     1620

aaccaaucac ucgcauucau ucguaaaucc gacgaacucc uacacaacgu gaaugcaggc     1680

aaaucgacca cuaacaucau gaucaccacc aucaucaucg ucaucauagu cauccuccug     1740

ucccuuaucg ccgucggucu uuuauuauac ugcaaagccc gcagcacccc cgucacccuc     1800

ucuaaggacc aacucagcgg caucaauaac aucgcauucu cuaacuaagg acuaguaaua     1860

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1920

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1187
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1187
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1188
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1188
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcuc cacgcccgug acccugagca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1189
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1189
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1190
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1190
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccagguc uacacccgug acgcucagca aggaccagcu guccgggaua     1800

aacaauaucg cuuuuucaaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1191
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1191
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1192
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1192
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccgguc cacccccgug acgcuuagca aggaccagcu gucuggaauu     1800

aacaauaucg cuuuuuccaa cugaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1193
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1193
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuauu aauccucaaa      120

gcgaacgcua uuacuaccau ucuaacagca gucacauucu gcuucgccuc aggccaaaac      180

auuacagaag aauuuuacca aucaacaugc ucugccguau caaaaggcua ccuauccgcc      240

cuacgaacag gcugguacac aagcguaaua acaaucgaac uaucaaacau aaaagaaaac      300

aaaugcaacg guacagacgc caaaguuaaa cuaauaaaac aagaacucga uaaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaucaacac cugcaacaaa caauagagcc      420

aggagagaau uaccucgauu caugaauuac acacucaaua acgcaaaaaa aaccaacguu      480

acacuaucaa aaaaaagaaa acgacgauuc uuaggauucc uacucggagu cggaucagca      540

auagcaucug gcguugcagu augcaaagua uuacacuuag aaggugaagu caauaaaaua      600

aaaagcgcgc uacuaaguac aaacaaagca gucgucuccc uaucaaacgg agucucaguc      660

cuaacauuca aaguacucga ccuaaaaaau uacauagaua aacaacuacu uccaauauua      720

aacaaacaau ccuguagcau cagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      780

aaccgauuau uagaaaucac ucgagaauuu uccguaaacg ccgggguaac aacuccaguc      840

ucaaccuaca ugcuaaccaa uucagaacua uugagcuuaa uaaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gucuaacaau guucaaaucg ucagacaaca aaguuacagu      960

auaaugugua uaaucaaaga agaaguccua gcauacguag uccaacuccc acuauaugga     1020

guuaucgaca caccauguug gaaauuacac accucaccau uaugcacaac caauacaaaa     1080

gaaggaucaa acauaugccu uacacggaca gaccgcggau gguauuguga caacgcuggc     1140

ucagucuccu uuuucccaca agcagaaaca ugcaaaguac aaucaaacag agucuuuugc     1200

gauaccauga acucacuuac auuaccaagc gaaguaaauc uuuguaacgu cgacaucuuc     1260

aauccuaaau augacugcaa aaucaugacc ucaaaaacag acguuagcuc uucaguaauc     1320

acuagcuuag gagcaaucgu aucaugcuac ggcaaaacaa aauguacagc aucaaauaaa     1380

aacagaggaa ucauaaaaac auuuucaaac ggaugcgauu auguaagcaa caaaggagua     1440

gauacuguaa gcguaggaaa cacauuguac uauguaaaca aacaagaagg aaaaucacuc     1500

uauguaaaag gagaaccuau aaucaauuuc uacgauccau uaguguuccc aucagaugaa     1560

uuugacgccu caauaucaca aguuaaugaa aaaauaaauc aaucgcuagc auucauacgu     1620

aaaucagaug aauuacuaca uaacguaaac gcaggcaaau ccacaacaaa uaucaugauc     1680

acaacaauua uaauaguaau aauaguaaua cuacuaucac uaauagccgu aggacuccua     1740

cuauacugca aagcaagauc uacuccagua acccucucaa aagaucaacu aagcggaauu     1800

aauaacaucg cauucagcaa cuaaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1194
<211>  2087
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1194
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu uauccucaaa      120

gccaacgcca ucaccaccau ccucacagca guaaccuuuu gcuucgccuc aggccaaaau      180

aucacagaag aauuuuacca gaguaccugc uccgccguau ccaaaggaua ccucagcgcg      240

cuccgcaccg gcugguacac uucaguaauc acaaucgaac uauccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aaugccguaa cagaacuaca acuguuaaug cagagcacac ccgccaccaa caaccgcgcc      420

cgccgggaac ucccccgauu caugaacuac acacucaaca acgccaaaaa gacgaacguc      480

acccucagca agaaacgaaa acgcagauuc cucgguuucc uacuaggcgu aggcucagca      540

auagccuccg gaguagccgu cugcaaaguc cugcacuuag aaggcgaagu caacaaaauc      600

aaauccgccc uacucuccac gaacaaagcc gucgucuccc uguccaacgg ugucuccguu      660

uuaaccuuca aaguucugga ccucaaaaac uacauagaca aacagcuucu ccccauccuc      720

aacaaacaau ccuguagcau cuccaacauc gaaaccguca uagaauuuca acagaaaaac      780

aacagacugc ucgaaaucac ccgcgaguuc uccgucaacg ccggcgucac gacucccguc      840

uccaccuaua ugcucacgaa cucggaacuc cuuucccuaa ucaacgacau gccgaucacc      900

aacgaccaaa agaaacucau gucaaacaac guacaaauug uccgccaaca aucauacucc      960

aucaugugca uaauuaaaga agaaguccuc gcauacguag uccaacuccc ccucuacggc     1020

gucaucgaca cccccugcug gaaacuccac accuccccac ucugcacaac caacaccaaa     1080

gaaggcucaa acauaugccu aacgcgcacc gaucgcgguu gguacugcga caacgccggu     1140

uccgucagcu ucuuccccca agcagagaca ugcaaagucc aaucaaaccg cgucuucugc     1200

gacaccauga acucacuaac ccuuccaagc gaagucaacc ucugcaacgu ugacaucuuc     1260

aaccccaaau acgacuguaa aaucaugacc uccaagaccg acguauccuc uuccgucauc     1320

acaucccuag gcgcuaucgu auccugcuau gguaaaacca aaugcaccgc cuccaacaaa     1380

aaccgcggca ucaucaagac auuuuccaac ggcugcgacu acgugagcaa caaaggcguc     1440

gacaccgucu ccguaggcaa cacccucuac uauguaaaca aacaagaggg caaaucacuc     1500

uacgucaaag gggaacccau caucaacuuc uacgacccgc ucguauuccc cagcgaugag     1560

uucgacgccu ccaucuccca ggucaacgaa aagauaaacc aaucacucgc auucauucgu     1620

aaauccgacg aacuccuaca caacgugaau gcaggcaaau cgaccacuaa caucaugauc     1680

accaccauca ucaucgucau cauagucauc cuccuguccc uuaucgccgu cggucuuuua     1740

uuauacugca aagcccgcag cacccccguc acccucucua aggaccaacu cagcggcauc     1800

aauaacaucg cauucucuaa cuaaggacua guaauaagga aacuguauga augucugugg     1860

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1920

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     2040

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2087


<210>  1195
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1195
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1196
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1196
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcuc cacgcccgug acccugagca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1197
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1197
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1198
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1198
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccagguc uacacccgug acgcucagca aggaccagcu guccgggaua     1800

aacaauaucg cuuuuucaaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1199
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1199
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1200
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1200
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccgguc cacccccgug acgcuuagca aggaccagcu gucuggaauu     1800

aacaauaucg cuuuuuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1201
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1201
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuauu aauccucaaa      120

gcgaacgcua uuacuaccau ucuaacagca gucacauucu gcuucgccuc aggccaaaac      180

auuacagaag aauuuuacca aucaacaugc ucugccguau caaaaggcua ccuauccgcc      240

cuacgaacag gcugguacac aagcguaaua acaaucgaac uaucaaacau aaaagaaaac      300

aaaugcaacg guacagacgc caaaguuaaa cuaauaaaac aagaacucga uaaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaucaacac cugcaacaaa caauagagcc      420

aggagagaau uaccucgauu caugaauuac acacucaaua acgcaaaaaa aaccaacguu      480

acacuaucaa aaaaaagaaa acgacgauuc uuaggauucc uacucggagu cggaucagca      540

auagcaucug gcguugcagu augcaaagua uuacacuuag aaggugaagu caauaaaaua      600

aaaagcgcgc uacuaaguac aaacaaagca gucgucuccc uaucaaacgg agucucaguc      660

cuaacauuca aaguacucga ccuaaaaaau uacauagaua aacaacuacu uccaauauua      720

aacaaacaau ccuguagcau cagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      780

aaccgauuau uagaaaucac ucgagaauuu uccguaaacg ccgggguaac aacuccaguc      840

ucaaccuaca ugcuaaccaa uucagaacua uugagcuuaa uaaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gucuaacaau guucaaaucg ucagacaaca aaguuacagu      960

auaaugugua uaaucaaaga agaaguccua gcauacguag uccaacuccc acuauaugga     1020

guuaucgaca caccauguug gaaauuacac accucaccau uaugcacaac caauacaaaa     1080

gaaggaucaa acauaugccu uacacggaca gaccgcggau gguauuguga caacgcuggc     1140

ucagucuccu uuuucccaca agcagaaaca ugcaaaguac aaucaaacag agucuuuugc     1200

gauaccauga acucacuuac auuaccaagc gaaguaaauc uuuguaacgu cgacaucuuc     1260

aauccuaaau augacugcaa aaucaugacc ucaaaaacag acguuagcuc uucaguaauc     1320

acuagcuuag gagcaaucgu aucaugcuac ggcaaaacaa aauguacagc aucaaauaaa     1380

aacagaggaa ucauaaaaac auuuucaaac ggaugcgauu auguaagcaa caaaggagua     1440

gauacuguaa gcguaggaaa cacauuguac uauguaaaca aacaagaagg aaaaucacuc     1500

uauguaaaag gagaaccuau aaucaauuuc uacgauccau uaguguuccc aucagaugaa     1560

uuugacgccu caauaucaca aguuaaugaa aaaauaaauc aaucgcuagc auucauacgu     1620

aaaucagaug aauuacuaca uaacguaaac gcaggcaaau ccacaacaaa uaucaugauc     1680

acaacaauua uaauaguaau aauaguaaua cuacuaucac uaauagccgu aggacuccua     1740

cuauacugca aagcaagauc uacuccagua acccucucaa aagaucaacu aagcggaauu     1800

aauaacaucg cauucagcaa cuaaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1202
<211>  2103
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1202
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu uauccucaaa      120

gccaacgcca ucaccaccau ccucacagca guaaccuuuu gcuucgccuc aggccaaaau      180

aucacagaag aauuuuacca gaguaccugc uccgccguau ccaaaggaua ccucagcgcg      240

cuccgcaccg gcugguacac uucaguaauc acaaucgaac uauccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aaugccguaa cagaacuaca acuguuaaug cagagcacac ccgccaccaa caaccgcgcc      420

cgccgggaac ucccccgauu caugaacuac acacucaaca acgccaaaaa gacgaacguc      480

acccucagca agaaacgaaa acgcagauuc cucgguuucc uacuaggcgu aggcucagca      540

auagccuccg gaguagccgu cugcaaaguc cugcacuuag aaggcgaagu caacaaaauc      600

aaauccgccc uacucuccac gaacaaagcc gucgucuccc uguccaacgg ugucuccguu      660

uuaaccuuca aaguucugga ccucaaaaac uacauagaca aacagcuucu ccccauccuc      720

aacaaacaau ccuguagcau cuccaacauc gaaaccguca uagaauuuca acagaaaaac      780

aacagacugc ucgaaaucac ccgcgaguuc uccgucaacg ccggcgucac gacucccguc      840

uccaccuaua ugcucacgaa cucggaacuc cuuucccuaa ucaacgacau gccgaucacc      900

aacgaccaaa agaaacucau gucaaacaac guacaaauug uccgccaaca aucauacucc      960

aucaugugca uaauuaaaga agaaguccuc gcauacguag uccaacuccc ccucuacggc     1020

gucaucgaca cccccugcug gaaacuccac accuccccac ucugcacaac caacaccaaa     1080

gaaggcucaa acauaugccu aacgcgcacc gaucgcgguu gguacugcga caacgccggu     1140

uccgucagcu ucuuccccca agcagagaca ugcaaagucc aaucaaaccg cgucuucugc     1200

gacaccauga acucacuaac ccuuccaagc gaagucaacc ucugcaacgu ugacaucuuc     1260

aaccccaaau acgacuguaa aaucaugacc uccaagaccg acguauccuc uuccgucauc     1320

acaucccuag gcgcuaucgu auccugcuau gguaaaacca aaugcaccgc cuccaacaaa     1380

aaccgcggca ucaucaagac auuuuccaac ggcugcgacu acgugagcaa caaaggcguc     1440

gacaccgucu ccguaggcaa cacccucuac uauguaaaca aacaagaggg caaaucacuc     1500

uacgucaaag gggaacccau caucaacuuc uacgacccgc ucguauuccc cagcgaugag     1560

uucgacgccu ccaucuccca ggucaacgaa aagauaaacc aaucacucgc auucauucgu     1620

aaauccgacg aacuccuaca caacgugaau gcaggcaaau cgaccacuaa caucaugauc     1680

accaccauca ucaucgucau cauagucauc cuccuguccc uuaucgccgu cggucuuuua     1740

uuauacugca aagcccgcag cacccccguc acccucucua aggaccaacu cagcggcauc     1800

aauaacaucg cauucucuaa cuaaggacua guacuggcug caucucccuu uccucugucc     1860

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1920

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2040

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2100

auu                                                                   2103


<210>  1203
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1203
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1204
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1204
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcuc cacgcccgug acccugagca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1205
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1205
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1206
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1206
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccagguc uacacccgug acgcucagca aggaccagcu guccgggaua     1800

aacaauaucg cuuuuucaaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1207
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1207
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1208
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1208
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccgguc cacccccgug acgcuuagca aggaccagcu gucuggaauu     1800

aacaauaucg cuuuuuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1209
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1209
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuauu aauccucaaa      120

gcgaacgcua uuacuaccau ucuaacagca gucacauucu gcuucgccuc aggccaaaac      180

auuacagaag aauuuuacca aucaacaugc ucugccguau caaaaggcua ccuauccgcc      240

cuacgaacag gcugguacac aagcguaaua acaaucgaac uaucaaacau aaaagaaaac      300

aaaugcaacg guacagacgc caaaguuaaa cuaauaaaac aagaacucga uaaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaucaacac cugcaacaaa caauagagcc      420

aggagagaau uaccucgauu caugaauuac acacucaaua acgcaaaaaa aaccaacguu      480

acacuaucaa aaaaaagaaa acgacgauuc uuaggauucc uacucggagu cggaucagca      540

auagcaucug gcguugcagu augcaaagua uuacacuuag aaggugaagu caauaaaaua      600

aaaagcgcgc uacuaaguac aaacaaagca gucgucuccc uaucaaacgg agucucaguc      660

cuaacauuca aaguacucga ccuaaaaaau uacauagaua aacaacuacu uccaauauua      720

aacaaacaau ccuguagcau cagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      780

aaccgauuau uagaaaucac ucgagaauuu uccguaaacg ccgggguaac aacuccaguc      840

ucaaccuaca ugcuaaccaa uucagaacua uugagcuuaa uaaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gucuaacaau guucaaaucg ucagacaaca aaguuacagu      960

auaaugugua uaaucaaaga agaaguccua gcauacguag uccaacuccc acuauaugga     1020

guuaucgaca caccauguug gaaauuacac accucaccau uaugcacaac caauacaaaa     1080

gaaggaucaa acauaugccu uacacggaca gaccgcggau gguauuguga caacgcuggc     1140

ucagucuccu uuuucccaca agcagaaaca ugcaaaguac aaucaaacag agucuuuugc     1200

gauaccauga acucacuuac auuaccaagc gaaguaaauc uuuguaacgu cgacaucuuc     1260

aauccuaaau augacugcaa aaucaugacc ucaaaaacag acguuagcuc uucaguaauc     1320

acuagcuuag gagcaaucgu aucaugcuac ggcaaaacaa aauguacagc aucaaauaaa     1380

aacagaggaa ucauaaaaac auuuucaaac ggaugcgauu auguaagcaa caaaggagua     1440

gauacuguaa gcguaggaaa cacauuguac uauguaaaca aacaagaagg aaaaucacuc     1500

uauguaaaag gagaaccuau aaucaauuuc uacgauccau uaguguuccc aucagaugaa     1560

uuugacgccu caauaucaca aguuaaugaa aaaauaaauc aaucgcuagc auucauacgu     1620

aaaucagaug aauuacuaca uaacguaaac gcaggcaaau ccacaacaaa uaucaugauc     1680

acaacaauua uaauaguaau aauaguaaua cuacuaucac uaauagccgu aggacuccua     1740

cuauacugca aagcaagauc uacuccagua acccucucaa aagaucaacu aagcggaauu     1800

aauaacaucg cauucagcaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1210
<211>  2319
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1210
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu uauccucaaa      120

gccaacgcca ucaccaccau ccucacagca guaaccuuuu gcuucgccuc aggccaaaau      180

aucacagaag aauuuuacca gaguaccugc uccgccguau ccaaaggaua ccucagcgcg      240

cuccgcaccg gcugguacac uucaguaauc acaaucgaac uauccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aaugccguaa cagaacuaca acuguuaaug cagagcacac ccgccaccaa caaccgcgcc      420

cgccgggaac ucccccgauu caugaacuac acacucaaca acgccaaaaa gacgaacguc      480

acccucagca agaaacgaaa acgcagauuc cucgguuucc uacuaggcgu aggcucagca      540

auagccuccg gaguagccgu cugcaaaguc cugcacuuag aaggcgaagu caacaaaauc      600

aaauccgccc uacucuccac gaacaaagcc gucgucuccc uguccaacgg ugucuccguu      660

uuaaccuuca aaguucugga ccucaaaaac uacauagaca aacagcuucu ccccauccuc      720

aacaaacaau ccuguagcau cuccaacauc gaaaccguca uagaauuuca acagaaaaac      780

aacagacugc ucgaaaucac ccgcgaguuc uccgucaacg ccggcgucac gacucccguc      840

uccaccuaua ugcucacgaa cucggaacuc cuuucccuaa ucaacgacau gccgaucacc      900

aacgaccaaa agaaacucau gucaaacaac guacaaauug uccgccaaca aucauacucc      960

aucaugugca uaauuaaaga agaaguccuc gcauacguag uccaacuccc ccucuacggc     1020

gucaucgaca cccccugcug gaaacuccac accuccccac ucugcacaac caacaccaaa     1080

gaaggcucaa acauaugccu aacgcgcacc gaucgcgguu gguacugcga caacgccggu     1140

uccgucagcu ucuuccccca agcagagaca ugcaaagucc aaucaaaccg cgucuucugc     1200

gacaccauga acucacuaac ccuuccaagc gaagucaacc ucugcaacgu ugacaucuuc     1260

aaccccaaau acgacuguaa aaucaugacc uccaagaccg acguauccuc uuccgucauc     1320

acaucccuag gcgcuaucgu auccugcuau gguaaaacca aaugcaccgc cuccaacaaa     1380

aaccgcggca ucaucaagac auuuuccaac ggcugcgacu acgugagcaa caaaggcguc     1440

gacaccgucu ccguaggcaa cacccucuac uauguaaaca aacaagaggg caaaucacuc     1500

uacgucaaag gggaacccau caucaacuuc uacgacccgc ucguauuccc cagcgaugag     1560

uucgacgccu ccaucuccca ggucaacgaa aagauaaacc aaucacucgc auucauucgu     1620

aaauccgacg aacuccuaca caacgugaau gcaggcaaau cgaccacuaa caucaugauc     1680

accaccauca ucaucgucau cauagucauc cuccuguccc uuaucgccgu cggucuuuua     1740

uuauacugca aagcccgcag cacccccguc acccucucua aggaccaacu cagcggcauc     1800

aauaacaucg cauucucuaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1860

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1920

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1980

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     2040

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     2100

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2160

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2280

cccccccccc caaaggcucu uuucagagcc accagaauu                            2319


<210>  1211
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1211
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1800

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1212
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1212
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcuc cacgcccgug acccugagca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1213
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1213
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1800

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1214
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1214
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccagguc uacacccgug acgcucagca aggaccagcu guccgggaua     1800

aacaauaucg cuuuuucaaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1215
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1215
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1800

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1216
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1216
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccgguc cacccccgug acgcuuagca aggaccagcu gucuggaauu     1800

aacaauaucg cuuuuuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1217
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1217
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuauu aauccucaaa      120

gcgaacgcua uuacuaccau ucuaacagca gucacauucu gcuucgccuc aggccaaaac      180

auuacagaag aauuuuacca aucaacaugc ucugccguau caaaaggcua ccuauccgcc      240

cuacgaacag gcugguacac aagcguaaua acaaucgaac uaucaaacau aaaagaaaac      300

aaaugcaacg guacagacgc caaaguuaaa cuaauaaaac aagaacucga uaaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaucaacac cugcaacaaa caauagagcc      420

aggagagaau uaccucgauu caugaauuac acacucaaua acgcaaaaaa aaccaacguu      480

acacuaucaa aaaaaagaaa acgacgauuc uuaggauucc uacucggagu cggaucagca      540

auagcaucug gcguugcagu augcaaagua uuacacuuag aaggugaagu caauaaaaua      600

aaaagcgcgc uacuaaguac aaacaaagca gucgucuccc uaucaaacgg agucucaguc      660

cuaacauuca aaguacucga ccuaaaaaau uacauagaua aacaacuacu uccaauauua      720

aacaaacaau ccuguagcau cagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      780

aaccgauuau uagaaaucac ucgagaauuu uccguaaacg ccgggguaac aacuccaguc      840

ucaaccuaca ugcuaaccaa uucagaacua uugagcuuaa uaaacgacau gccaauaacc      900

aacgaccaaa aaaaacuaau gucuaacaau guucaaaucg ucagacaaca aaguuacagu      960

auaaugugua uaaucaaaga agaaguccua gcauacguag uccaacuccc acuauaugga     1020

guuaucgaca caccauguug gaaauuacac accucaccau uaugcacaac caauacaaaa     1080

gaaggaucaa acauaugccu uacacggaca gaccgcggau gguauuguga caacgcuggc     1140

ucagucuccu uuuucccaca agcagaaaca ugcaaaguac aaucaaacag agucuuuugc     1200

gauaccauga acucacuuac auuaccaagc gaaguaaauc uuuguaacgu cgacaucuuc     1260

aauccuaaau augacugcaa aaucaugacc ucaaaaacag acguuagcuc uucaguaauc     1320

acuagcuuag gagcaaucgu aucaugcuac ggcaaaacaa aauguacagc aucaaauaaa     1380

aacagaggaa ucauaaaaac auuuucaaac ggaugcgauu auguaagcaa caaaggagua     1440

gauacuguaa gcguaggaaa cacauuguac uauguaaaca aacaagaagg aaaaucacuc     1500

uauguaaaag gagaaccuau aaucaauuuc uacgauccau uaguguuccc aucagaugaa     1560

uuugacgccu caauaucaca aguuaaugaa aaaauaaauc aaucgcuagc auucauacgu     1620

aaaucagaug aauuacuaca uaacguaaac gcaggcaaau ccacaacaaa uaucaugauc     1680

acaacaauua uaauaguaau aauaguaaua cuacuaucac uaauagccgu aggacuccua     1740

cuauacugca aagcaagauc uacuccagua acccucucaa aagaucaacu aagcggaauu     1800

aauaacaucg cauucagcaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1218
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1218
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu uauccucaaa      120

gccaacgcca ucaccaccau ccucacagca guaaccuuuu gcuucgccuc aggccaaaau      180

aucacagaag aauuuuacca gaguaccugc uccgccguau ccaaaggaua ccucagcgcg      240

cuccgcaccg gcugguacac uucaguaauc acaaucgaac uauccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aaugccguaa cagaacuaca acuguuaaug cagagcacac ccgccaccaa caaccgcgcc      420

cgccgggaac ucccccgauu caugaacuac acacucaaca acgccaaaaa gacgaacguc      480

acccucagca agaaacgaaa acgcagauuc cucgguuucc uacuaggcgu aggcucagca      540

auagccuccg gaguagccgu cugcaaaguc cugcacuuag aaggcgaagu caacaaaauc      600

aaauccgccc uacucuccac gaacaaagcc gucgucuccc uguccaacgg ugucuccguu      660

uuaaccuuca aaguucugga ccucaaaaac uacauagaca aacagcuucu ccccauccuc      720

aacaaacaau ccuguagcau cuccaacauc gaaaccguca uagaauuuca acagaaaaac      780

aacagacugc ucgaaaucac ccgcgaguuc uccgucaacg ccggcgucac gacucccguc      840

uccaccuaua ugcucacgaa cucggaacuc cuuucccuaa ucaacgacau gccgaucacc      900

aacgaccaaa agaaacucau gucaaacaac guacaaauug uccgccaaca aucauacucc      960

aucaugugca uaauuaaaga agaaguccuc gcauacguag uccaacuccc ccucuacggc     1020

gucaucgaca cccccugcug gaaacuccac accuccccac ucugcacaac caacaccaaa     1080

gaaggcucaa acauaugccu aacgcgcacc gaucgcgguu gguacugcga caacgccggu     1140

uccgucagcu ucuuccccca agcagagaca ugcaaagucc aaucaaaccg cgucuucugc     1200

gacaccauga acucacuaac ccuuccaagc gaagucaacc ucugcaacgu ugacaucuuc     1260

aaccccaaau acgacuguaa aaucaugacc uccaagaccg acguauccuc uuccgucauc     1320

acaucccuag gcgcuaucgu auccugcuau gguaaaacca aaugcaccgc cuccaacaaa     1380

aaccgcggca ucaucaagac auuuuccaac ggcugcgacu acgugagcaa caaaggcguc     1440

gacaccgucu ccguaggcaa cacccucuac uauguaaaca aacaagaggg caaaucacuc     1500

uacgucaaag gggaacccau caucaacuuc uacgacccgc ucguauuccc cagcgaugag     1560

uucgacgccu ccaucuccca ggucaacgaa aagauaaacc aaucacucgc auucauucgu     1620

aaauccgacg aacuccuaca caacgugaau gcaggcaaau cgaccacuaa caucaugauc     1680

accaccauca ucaucgucau cauagucauc cuccuguccc uuaucgccgu cggucuuuua     1740

uuauacugca aagcccgcag cacccccguc acccucucua aggaccaacu cagcggcauc     1800

aauaacaucg cauucucuaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1860

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1920

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1219
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1219
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1220
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1220
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcuccacgc ccgugacccu gagcaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc agcaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1221
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1221
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1222
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1222
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggucuacac ccgugacgcu cagcaaggac     1860

cagcuguccg ggauaaacaa uaucgcuuuu ucaaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1223
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1223
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1224
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1224
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cgguccaccc ccgugacgcu uagcaaggac     1860

cagcugucug gaauuaacaa uaucgcuuuu uccaacugag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1225
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1225
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuauuaaucc ucaaagcgaa cgcuauuacu accauucuaa cagcagucac auucugcuuc      240

gccucaggcc aaaacauuac agaagaauuu uaccaaucaa caugcucugc cguaucaaaa      300

ggcuaccuau ccgcccuacg aacaggcugg uacacaagcg uaauaacaau cgaacuauca      360

aacauaaaag aaaacaaaug caacgguaca gacgccaaag uuaaacuaau aaaacaagaa      420

cucgauaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaauc aacaccugca      480

acaaacaaua gagccaggag agaauuaccu cgauucauga auuacacacu caauaacgca      540

aaaaaaacca acguuacacu aucaaaaaaa agaaaacgac gauucuuagg auuccuacuc      600

ggagucggau cagcaauagc aucuggcguu gcaguaugca aaguauuaca cuuagaaggu      660

gaagucaaua aaauaaaaag cgcgcuacua aguacaaaca aagcagucgu cucccuauca      720

aacggagucu caguccuaac auucaaagua cucgaccuaa aaaauuacau agauaaacaa      780

cuacuuccaa uauuaaacaa acaauccugu agcaucagca auauagaaac aguaauagaa      840

uuucaacaaa aaaacaaccg auuauuagaa aucacucgag aauuuuccgu aaacgccggg      900

guaacaacuc cagucucaac cuacaugcua accaauucag aacuauugag cuuaauaaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugucua acaauguuca aaucgucaga     1020

caacaaaguu acaguauaau guguauaauc aaagaagaag uccuagcaua cguaguccaa     1080

cucccacuau auggaguuau cgacacacca uguuggaaau uacacaccuc accauuaugc     1140

acaaccaaua caaaagaagg aucaaacaua ugccuuacac ggacagaccg cggaugguau     1200

ugugacaacg cuggcucagu cuccuuuuuc ccacaagcag aaacaugcaa aguacaauca     1260

aacagagucu uuugcgauac caugaacuca cuuacauuac caagcgaagu aaaucuuugu     1320

aacgucgaca ucuucaaucc uaaauaugac ugcaaaauca ugaccucaaa aacagacguu     1380

agcucuucag uaaucacuag cuuaggagca aucguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa auaaaaacag aggaaucaua aaaacauuuu caaacggaug cgauuaugua     1500

agcaacaaag gaguagauac uguaagcgua ggaaacacau uguacuaugu aaacaaacaa     1560

gaaggaaaau cacucuaugu aaaaggagaa ccuauaauca auuucuacga uccauuagug     1620

uucccaucag augaauuuga cgccucaaua ucacaaguua augaaaaaau aaaucaaucg     1680

cuagcauuca uacguaaauc agaugaauua cuacauaacg uaaacgcagg caaauccaca     1740

acaaauauca ugaucacaac aauuauaaua guaauaauag uaauacuacu aucacuaaua     1800

gccguaggac uccuacuaua cugcaaagca agaucuacuc caguaacccu cucaaaagau     1860

caacuaagcg gaauuaauaa caucgcauuc agcaacuaag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1226
<211>  2162
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1226
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuuaucc ucaaagccaa cgccaucacc accauccuca cagcaguaac cuuuugcuuc      240

gccucaggcc aaaauaucac agaagaauuu uaccagagua ccugcuccgc cguauccaaa      300

ggauaccuca gcgcgcuccg caccggcugg uacacuucag uaaucacaau cgaacuaucc      360

aacaucaaag aaaacaaaug caacggcacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaaugc cguaacagaa cuacaacugu uaaugcagag cacacccgcc      480

accaacaacc gcgcccgccg ggaacucccc cgauucauga acuacacacu caacaacgcc      540

aaaaagacga acgucacccu cagcaagaaa cgaaaacgca gauuccucgg uuuccuacua      600

ggcguaggcu cagcaauagc cuccggagua gccgucugca aaguccugca cuuagaaggc      660

gaagucaaca aaaucaaauc cgcccuacuc uccacgaaca aagccgucgu cucccugucc      720

aacggugucu ccguuuuaac cuucaaaguu cuggaccuca aaaacuacau agacaaacag      780

cuucucccca uccucaacaa acaauccugu agcaucucca acaucgaaac cgucauagaa      840

uuucaacaga aaaacaacag acugcucgaa aucacccgcg aguucuccgu caacgccggc      900

gucacgacuc ccgucuccac cuauaugcuc acgaacucgg aacuccuuuc ccuaaucaac      960

gacaugccga ucaccaacga ccaaaagaaa cucaugucaa acaacguaca aauuguccgc     1020

caacaaucau acuccaucau gugcauaauu aaagaagaag uccucgcaua cguaguccaa     1080

cucccccucu acggcgucau cgacaccccc ugcuggaaac uccacaccuc cccacucugc     1140

acaaccaaca ccaaagaagg cucaaacaua ugccuaacgc gcaccgaucg cgguugguac     1200

ugcgacaacg ccgguuccgu cagcuucuuc ccccaagcag agacaugcaa aguccaauca     1260

aaccgcgucu ucugcgacac caugaacuca cuaacccuuc caagcgaagu caaccucugc     1320

aacguugaca ucuucaaccc caaauacgac uguaaaauca ugaccuccaa gaccgacgua     1380

uccucuuccg ucaucacauc ccuaggcgcu aucguauccu gcuaugguaa aaccaaaugc     1440

accgccucca acaaaaaccg cggcaucauc aagacauuuu ccaacggcug cgacuacgug     1500

agcaacaaag gcgucgacac cgucuccgua ggcaacaccc ucuacuaugu aaacaaacaa     1560

gagggcaaau cacucuacgu caaaggggaa cccaucauca acuucuacga cccgcucgua     1620

uuccccagcg augaguucga cgccuccauc ucccagguca acgaaaagau aaaccaauca     1680

cucgcauuca uucguaaauc cgacgaacuc cuacacaacg ugaaugcagg caaaucgacc     1740

acuaacauca ugaucaccac caucaucauc gucaucauag ucauccuccu gucccuuauc     1800

gccgucgguc uuuuauuaua cugcaaagcc cgcagcaccc ccgucacccu cucuaaggac     1860

caacucagcg gcaucaauaa caucgcauuc ucuaacuaag gacuaguaau aaggaaacug     1920

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1980

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     2100

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     2160

uu                                                                    2162


<210>  1227
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1227
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1228
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1228
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcuccacgc ccgugacccu gagcaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc agcaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1229
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1229
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1230
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1230
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggucuacac ccgugacgcu cagcaaggac     1860

cagcuguccg ggauaaacaa uaucgcuuuu ucaaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1231
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1231
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1232
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1232
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cgguccaccc ccgugacgcu uagcaaggac     1860

cagcugucug gaauuaacaa uaucgcuuuu uccaacugag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1233
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1233
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuauuaaucc ucaaagcgaa cgcuauuacu accauucuaa cagcagucac auucugcuuc      240

gccucaggcc aaaacauuac agaagaauuu uaccaaucaa caugcucugc cguaucaaaa      300

ggcuaccuau ccgcccuacg aacaggcugg uacacaagcg uaauaacaau cgaacuauca      360

aacauaaaag aaaacaaaug caacgguaca gacgccaaag uuaaacuaau aaaacaagaa      420

cucgauaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaauc aacaccugca      480

acaaacaaua gagccaggag agaauuaccu cgauucauga auuacacacu caauaacgca      540

aaaaaaacca acguuacacu aucaaaaaaa agaaaacgac gauucuuagg auuccuacuc      600

ggagucggau cagcaauagc aucuggcguu gcaguaugca aaguauuaca cuuagaaggu      660

gaagucaaua aaauaaaaag cgcgcuacua aguacaaaca aagcagucgu cucccuauca      720

aacggagucu caguccuaac auucaaagua cucgaccuaa aaaauuacau agauaaacaa      780

cuacuuccaa uauuaaacaa acaauccugu agcaucagca auauagaaac aguaauagaa      840

uuucaacaaa aaaacaaccg auuauuagaa aucacucgag aauuuuccgu aaacgccggg      900

guaacaacuc cagucucaac cuacaugcua accaauucag aacuauugag cuuaauaaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugucua acaauguuca aaucgucaga     1020

caacaaaguu acaguauaau guguauaauc aaagaagaag uccuagcaua cguaguccaa     1080

cucccacuau auggaguuau cgacacacca uguuggaaau uacacaccuc accauuaugc     1140

acaaccaaua caaaagaagg aucaaacaua ugccuuacac ggacagaccg cggaugguau     1200

ugugacaacg cuggcucagu cuccuuuuuc ccacaagcag aaacaugcaa aguacaauca     1260

aacagagucu uuugcgauac caugaacuca cuuacauuac caagcgaagu aaaucuuugu     1320

aacgucgaca ucuucaaucc uaaauaugac ugcaaaauca ugaccucaaa aacagacguu     1380

agcucuucag uaaucacuag cuuaggagca aucguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa auaaaaacag aggaaucaua aaaacauuuu caaacggaug cgauuaugua     1500

agcaacaaag gaguagauac uguaagcgua ggaaacacau uguacuaugu aaacaaacaa     1560

gaaggaaaau cacucuaugu aaaaggagaa ccuauaauca auuucuacga uccauuagug     1620

uucccaucag augaauuuga cgccucaaua ucacaaguua augaaaaaau aaaucaaucg     1680

cuagcauuca uacguaaauc agaugaauua cuacauaacg uaaacgcagg caaauccaca     1740

acaaauauca ugaucacaac aauuauaaua guaauaauag uaauacuacu aucacuaaua     1800

gccguaggac uccuacuaua cugcaaagca agaucuacuc caguaacccu cucaaaagau     1860

caacuaagcg gaauuaauaa caucgcauuc agcaacuaag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1234
<211>  2178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1234
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuuaucc ucaaagccaa cgccaucacc accauccuca cagcaguaac cuuuugcuuc      240

gccucaggcc aaaauaucac agaagaauuu uaccagagua ccugcuccgc cguauccaaa      300

ggauaccuca gcgcgcuccg caccggcugg uacacuucag uaaucacaau cgaacuaucc      360

aacaucaaag aaaacaaaug caacggcacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaaugc cguaacagaa cuacaacugu uaaugcagag cacacccgcc      480

accaacaacc gcgcccgccg ggaacucccc cgauucauga acuacacacu caacaacgcc      540

aaaaagacga acgucacccu cagcaagaaa cgaaaacgca gauuccucgg uuuccuacua      600

ggcguaggcu cagcaauagc cuccggagua gccgucugca aaguccugca cuuagaaggc      660

gaagucaaca aaaucaaauc cgcccuacuc uccacgaaca aagccgucgu cucccugucc      720

aacggugucu ccguuuuaac cuucaaaguu cuggaccuca aaaacuacau agacaaacag      780

cuucucccca uccucaacaa acaauccugu agcaucucca acaucgaaac cgucauagaa      840

uuucaacaga aaaacaacag acugcucgaa aucacccgcg aguucuccgu caacgccggc      900

gucacgacuc ccgucuccac cuauaugcuc acgaacucgg aacuccuuuc ccuaaucaac      960

gacaugccga ucaccaacga ccaaaagaaa cucaugucaa acaacguaca aauuguccgc     1020

caacaaucau acuccaucau gugcauaauu aaagaagaag uccucgcaua cguaguccaa     1080

cucccccucu acggcgucau cgacaccccc ugcuggaaac uccacaccuc cccacucugc     1140

acaaccaaca ccaaagaagg cucaaacaua ugccuaacgc gcaccgaucg cgguugguac     1200

ugcgacaacg ccgguuccgu cagcuucuuc ccccaagcag agacaugcaa aguccaauca     1260

aaccgcgucu ucugcgacac caugaacuca cuaacccuuc caagcgaagu caaccucugc     1320

aacguugaca ucuucaaccc caaauacgac uguaaaauca ugaccuccaa gaccgacgua     1380

uccucuuccg ucaucacauc ccuaggcgcu aucguauccu gcuaugguaa aaccaaaugc     1440

accgccucca acaaaaaccg cggcaucauc aagacauuuu ccaacggcug cgacuacgug     1500

agcaacaaag gcgucgacac cgucuccgua ggcaacaccc ucuacuaugu aaacaaacaa     1560

gagggcaaau cacucuacgu caaaggggaa cccaucauca acuucuacga cccgcucgua     1620

uuccccagcg augaguucga cgccuccauc ucccagguca acgaaaagau aaaccaauca     1680

cucgcauuca uucguaaauc cgacgaacuc cuacacaacg ugaaugcagg caaaucgacc     1740

acuaacauca ugaucaccac caucaucauc gucaucauag ucauccuccu gucccuuauc     1800

gccgucgguc uuuuauuaua cugcaaagcc cgcagcaccc ccgucacccu cucuaaggac     1860

caacucagcg gcaucaauaa caucgcauuc ucuaacuaag gacuaguacu ggcugcaucu     1920

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1980

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     2040

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     2160

uucagagcca ccagaauu                                                   2178


<210>  1235
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1235
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggagcacgc ccgucacccu guccaaggac     1860

cagcugagcg gcaucaacaa caucgcguuc uccaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1236
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1236
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcuccacgc ccgugacccu gagcaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc agcaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1237
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1237
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcuccaccc ccgucacccu cuccaaggac     1860

cagcucuccg gcaucaacaa caucgccuuc uccaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1238
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1238
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggucuacac ccgugacgcu cagcaaggac     1860

cagcuguccg ggauaaacaa uaucgcuuuu ucaaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1239
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1239
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaagcaccc ccgugacccu gagcaaggac     1860

cagcugagcg gcaucaacaa caucgccuuc agcaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1240
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1240
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cgguccaccc ccgugacgcu uagcaaggac     1860

cagcugucug gaauuaacaa uaucgcuuuu uccaacugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1241
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1241
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuauuaaucc ucaaagcgaa cgcuauuacu accauucuaa cagcagucac auucugcuuc      240

gccucaggcc aaaacauuac agaagaauuu uaccaaucaa caugcucugc cguaucaaaa      300

ggcuaccuau ccgcccuacg aacaggcugg uacacaagcg uaauaacaau cgaacuauca      360

aacauaaaag aaaacaaaug caacgguaca gacgccaaag uuaaacuaau aaaacaagaa      420

cucgauaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaauc aacaccugca      480

acaaacaaua gagccaggag agaauuaccu cgauucauga auuacacacu caauaacgca      540

aaaaaaacca acguuacacu aucaaaaaaa agaaaacgac gauucuuagg auuccuacuc      600

ggagucggau cagcaauagc aucuggcguu gcaguaugca aaguauuaca cuuagaaggu      660

gaagucaaua aaauaaaaag cgcgcuacua aguacaaaca aagcagucgu cucccuauca      720

aacggagucu caguccuaac auucaaagua cucgaccuaa aaaauuacau agauaaacaa      780

cuacuuccaa uauuaaacaa acaauccugu agcaucagca auauagaaac aguaauagaa      840

uuucaacaaa aaaacaaccg auuauuagaa aucacucgag aauuuuccgu aaacgccggg      900

guaacaacuc cagucucaac cuacaugcua accaauucag aacuauugag cuuaauaaac      960

gacaugccaa uaaccaacga ccaaaaaaaa cuaaugucua acaauguuca aaucgucaga     1020

caacaaaguu acaguauaau guguauaauc aaagaagaag uccuagcaua cguaguccaa     1080

cucccacuau auggaguuau cgacacacca uguuggaaau uacacaccuc accauuaugc     1140

acaaccaaua caaaagaagg aucaaacaua ugccuuacac ggacagaccg cggaugguau     1200

ugugacaacg cuggcucagu cuccuuuuuc ccacaagcag aaacaugcaa aguacaauca     1260

aacagagucu uuugcgauac caugaacuca cuuacauuac caagcgaagu aaaucuuugu     1320

aacgucgaca ucuucaaucc uaaauaugac ugcaaaauca ugaccucaaa aacagacguu     1380

agcucuucag uaaucacuag cuuaggagca aucguaucau gcuacggcaa aacaaaaugu     1440

acagcaucaa auaaaaacag aggaaucaua aaaacauuuu caaacggaug cgauuaugua     1500

agcaacaaag gaguagauac uguaagcgua ggaaacacau uguacuaugu aaacaaacaa     1560

gaaggaaaau cacucuaugu aaaaggagaa ccuauaauca auuucuacga uccauuagug     1620

uucccaucag augaauuuga cgccucaaua ucacaaguua augaaaaaau aaaucaaucg     1680

cuagcauuca uacguaaauc agaugaauua cuacauaacg uaaacgcagg caaauccaca     1740

acaaauauca ugaucacaac aauuauaaua guaauaauag uaauacuacu aucacuaaua     1800

gccguaggac uccuacuaua cugcaaagca agaucuacuc caguaacccu cucaaaagau     1860

caacuaagcg gaauuaauaa caucgcauuc agcaacuaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1242
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1242
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuuaucc ucaaagccaa cgccaucacc accauccuca cagcaguaac cuuuugcuuc      240

gccucaggcc aaaauaucac agaagaauuu uaccagagua ccugcuccgc cguauccaaa      300

ggauaccuca gcgcgcuccg caccggcugg uacacuucag uaaucacaau cgaacuaucc      360

aacaucaaag aaaacaaaug caacggcacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaaugc cguaacagaa cuacaacugu uaaugcagag cacacccgcc      480

accaacaacc gcgcccgccg ggaacucccc cgauucauga acuacacacu caacaacgcc      540

aaaaagacga acgucacccu cagcaagaaa cgaaaacgca gauuccucgg uuuccuacua      600

ggcguaggcu cagcaauagc cuccggagua gccgucugca aaguccugca cuuagaaggc      660

gaagucaaca aaaucaaauc cgcccuacuc uccacgaaca aagccgucgu cucccugucc      720

aacggugucu ccguuuuaac cuucaaaguu cuggaccuca aaaacuacau agacaaacag      780

cuucucccca uccucaacaa acaauccugu agcaucucca acaucgaaac cgucauagaa      840

uuucaacaga aaaacaacag acugcucgaa aucacccgcg aguucuccgu caacgccggc      900

gucacgacuc ccgucuccac cuauaugcuc acgaacucgg aacuccuuuc ccuaaucaac      960

gacaugccga ucaccaacga ccaaaagaaa cucaugucaa acaacguaca aauuguccgc     1020

caacaaucau acuccaucau gugcauaauu aaagaagaag uccucgcaua cguaguccaa     1080

cucccccucu acggcgucau cgacaccccc ugcuggaaac uccacaccuc cccacucugc     1140

acaaccaaca ccaaagaagg cucaaacaua ugccuaacgc gcaccgaucg cgguugguac     1200

ugcgacaacg ccgguuccgu cagcuucuuc ccccaagcag agacaugcaa aguccaauca     1260

aaccgcgucu ucugcgacac caugaacuca cuaacccuuc caagcgaagu caaccucugc     1320

aacguugaca ucuucaaccc caaauacgac uguaaaauca ugaccuccaa gaccgacgua     1380

uccucuuccg ucaucacauc ccuaggcgcu aucguauccu gcuaugguaa aaccaaaugc     1440

accgccucca acaaaaaccg cggcaucauc aagacauuuu ccaacggcug cgacuacgug     1500

agcaacaaag gcgucgacac cgucuccgua ggcaacaccc ucuacuaugu aaacaaacaa     1560

gagggcaaau cacucuacgu caaaggggaa cccaucauca acuucuacga cccgcucgua     1620

uuccccagcg augaguucga cgccuccauc ucccagguca acgaaaagau aaaccaauca     1680

cucgcauuca uucguaaauc cgacgaacuc cuacacaacg ugaaugcagg caaaucgacc     1740

acuaacauca ugaucaccac caucaucauc gucaucauag ucauccuccu gucccuuauc     1800

gccgucgguc uuuuauuaua cugcaaagcc cgcagcaccc ccgucacccu cucuaaggac     1860

caacucagcg gcaucaauaa caucgcauuc ucuaacuaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1243
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1243
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1244
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1244
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      600

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      720

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      780

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug      960

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1020

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1440

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1560

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1680

aucgccgucg ggcugcuccu guacugcaag gcgcgcucca cgcccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1245
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1245
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1246
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1246
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      600

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      720

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      780

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua      900

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug      960

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1020

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1080

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1140

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1200

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1260

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1320

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1380

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1440

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1500

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1560

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1620

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1680

aucgcuguag gccuucuguu guacugcaag gccaggucua cacccgugac gcucagcaag     1740

gaccagcugu ccgggauaaa caauaucgcu uuuucaaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1247
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1247
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1248
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1248
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      600

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      720

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      780

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug      900

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc      960

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1020

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1080

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1140

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1200

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1260

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1320

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1380

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1440

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1500

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1560

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1680

aucgcggucg ggcugcuccu guacugcaag gcccggucca cccccgugac gcuuagcaag     1740

gaccagcugu cuggaauuaa caauaucgcu uuuuccaacu gaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1249
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1249
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaauuauuaa uccucaaagc gaacgcuauu acuaccauuc uaacagcagu cacauucugc      120

uucgccucag gccaaaacau uacagaagaa uuuuaccaau caacaugcuc ugccguauca      180

aaaggcuacc uauccgcccu acgaacaggc ugguacacaa gcguaauaac aaucgaacua      240

ucaaacauaa aagaaaacaa augcaacggu acagacgcca aaguuaaacu aauaaaacaa      300

gaacucgaua aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aucaacaccu      360

gcaacaaaca auagagccag gagagaauua ccucgauuca ugaauuacac acucaauaac      420

gcaaaaaaaa ccaacguuac acuaucaaaa aaaagaaaac gacgauucuu aggauuccua      480

cucggagucg gaucagcaau agcaucuggc guugcaguau gcaaaguauu acacuuagaa      540

ggugaaguca auaaaauaaa aagcgcgcua cuaaguacaa acaaagcagu cgucucccua      600

ucaaacggag ucucaguccu aacauucaaa guacucgacc uaaaaaauua cauagauaaa      660

caacuacuuc caauauuaaa caaacaaucc uguagcauca gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa ccgauuauua gaaaucacuc gagaauuuuc cguaaacgcc      780

gggguaacaa cuccagucuc aaccuacaug cuaaccaauu cagaacuauu gagcuuaaua      840

aacgacaugc caauaaccaa cgaccaaaaa aaacuaaugu cuaacaaugu ucaaaucguc      900

agacaacaaa guuacaguau aauguguaua aucaaagaag aaguccuagc auacguaguc      960

caacucccac uauauggagu uaucgacaca ccauguugga aauuacacac cucaccauua     1020

ugcacaacca auacaaaaga aggaucaaac auaugccuua cacggacaga ccgcggaugg     1080

uauugugaca acgcuggcuc agucuccuuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag ucuuuugcga uaccaugaac ucacuuacau uaccaagcga aguaaaucuu     1200

uguaacgucg acaucuucaa uccuaaauau gacugcaaaa ucaugaccuc aaaaacagac     1260

guuagcucuu caguaaucac uagcuuagga gcaaucguau caugcuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa cagaggaauc auaaaaacau uuucaaacgg augcgauuau     1380

guaagcaaca aaggaguaga uacuguaagc guaggaaaca cauuguacua uguaaacaaa     1440

caagaaggaa aaucacucua uguaaaagga gaaccuauaa ucaauuucua cgauccauua     1500

guguucccau cagaugaauu ugacgccuca auaucacaag uuaaugaaaa aauaaaucaa     1560

ucgcuagcau ucauacguaa aucagaugaa uuacuacaua acguaaacgc aggcaaaucc     1620

acaacaaaua ucaugaucac aacaauuaua auaguaauaa uaguaauacu acuaucacua     1680

auagccguag gacuccuacu auacugcaaa gcaagaucua cuccaguaac ccucucaaaa     1740

gaucaacuaa gcggaauuaa uaacaucgca uucagcaacu aaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1250
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1250
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuua uccucaaagc caacgccauc accaccaucc ucacagcagu aaccuuuugc      120

uucgccucag gccaaaauau cacagaagaa uuuuaccaga guaccugcuc cgccguaucc      180

aaaggauacc ucagcgcgcu ccgcaccggc ugguacacuu caguaaucac aaucgaacua      240

uccaacauca aagaaaacaa augcaacggc accgacgcga aagucaaacu caucaaacaa      300

gaacuagaca aauacaaaaa ugccguaaca gaacuacaac uguuaaugca gagcacaccc      360

gccaccaaca accgcgcccg ccgggaacuc ccccgauuca ugaacuacac acucaacaac      420

gccaaaaaga cgaacgucac ccucagcaag aaacgaaaac gcagauuccu cgguuuccua      480

cuaggcguag gcucagcaau agccuccgga guagccgucu gcaaaguccu gcacuuagaa      540

ggcgaaguca acaaaaucaa auccgcccua cucuccacga acaaagccgu cgucucccug      600

uccaacggug ucuccguuuu aaccuucaaa guucuggacc ucaaaaacua cauagacaaa      660

cagcuucucc ccauccucaa caaacaaucc uguagcaucu ccaacaucga aaccgucaua      720

gaauuucaac agaaaaacaa cagacugcuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacga cucccgucuc caccuauaug cucacgaacu cggaacuccu uucccuaauc      840

aacgacaugc cgaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaauuguc      900

cgccaacaau cauacuccau caugugcaua auuaaagaag aaguccucgc auacguaguc      960

caacuccccc ucuacggcgu caucgacacc cccugcugga aacuccacac cuccccacuc     1020

ugcacaacca acaccaaaga aggcucaaac auaugccuaa cgcgcaccga ucgcgguugg     1080

uacugcgaca acgccgguuc cgucagcuuc uucccccaag cagagacaug caaaguccaa     1140

ucaaaccgcg ucuucugcga caccaugaac ucacuaaccc uuccaagcga agucaaccuc     1200

ugcaacguug acaucuucaa ccccaaauac gacuguaaaa ucaugaccuc caagaccgac     1260

guauccucuu ccgucaucac aucccuaggc gcuaucguau ccugcuaugg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgcggcauc aucaagacau uuuccaacgg cugcgacuac     1380

gugagcaaca aaggcgucga caccgucucc guaggcaaca cccucuacua uguaaacaaa     1440

caagagggca aaucacucua cgucaaaggg gaacccauca ucaacuucua cgacccgcuc     1500

guauucccca gcgaugaguu cgacgccucc aucucccagg ucaacgaaaa gauaaaccaa     1560

ucacucgcau ucauucguaa auccgacgaa cuccuacaca acgugaaugc aggcaaaucg     1620

accacuaaca ucaugaucac caccaucauc aucgucauca uagucauccu ccugucccuu     1680

aucgccgucg gucuuuuauu auacugcaaa gcccgcagca cccccgucac ccucucuaag     1740

gaccaacuca gcggcaucaa uaacaucgca uucucuaacu aaggacuagu gcaucacauu     1800

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1860

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1920

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1251
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1251
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc uuccuccugg      480

gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug agccucucca      600

acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg gugaucgagu      720

uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug aacgccgggg      780

ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc cugaucaacg      840

acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag aucguccggc      900

agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac gugguccagc      960

ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc ccccugugca     1020

ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg ggcugguacu     1080

gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag gugcagagca     1140

accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacguga     1260

gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag acgaagugca     1320

ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac ccgcuggucu     1500

uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc aagagcacga     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug ucccucaucg     1680

ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug uccaaggacc     1740

agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1252
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1252
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc uuccuccugg      480

gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug ucccucagca      600

acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg gucaucgagu      720

uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug aacgcggggg      780

ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc cucaucaacg      840

acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag aucgugcgcc      900

agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac guggugcagc      960

ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc ccccucugca     1020

ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc ggcugguacu     1080

gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag guccagucca     1140

accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug aaccugugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag accgacgugu     1260

ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag acgaagugca     1320

ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug aacaagcagg     1440

agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac ccccuggugu     1500

ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc aaccaguccc     1560

ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc aaguccacga     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc agccugaucg     1680

ccgucgggcu gcuccuguac ugcaaggcgc gcuccacgcc cgugacccug agcaaggacc     1740

agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1253
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1253
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc aacaacgcca      420

agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc uuccuccucg      480

gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac cucgagggcg      540

aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc ucccucucca      600

acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc gacaagcagc      660

uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc gucaucgagu      720

uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc aacgccggcg      780

ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc cucaucaacg      840

acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag aucguccgcc      900

agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac gucguccagc      960

ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc ccccucugca     1020

ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc ggcugguacu     1080

gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag guccagucca     1140

accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacgucu     1260

ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag accaagugca     1320

ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc gacuacgucu     1380

ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc aacaagcagg     1440

agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac ccccucgucu     1500

uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc aaccaguccc     1560

ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc aaguccacca     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc ucccucaucg     1680

ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc uccaaggacc     1740

agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1254
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1254
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc aauaacgcaa      420

agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc uuucucuuag      480

gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac cuugaaggug      540

aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua ucucuaagca      600

acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu gauaagcaac      660

uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc gugauagagu      720

uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug aaugccggag      780

ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc cugaucaaug      840

acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag aucguaagac      900

agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac gucgugcaac      960

ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc ccccuuugua     1020

ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg gggugguauu     1080

gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa guccagucaa     1140

accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua aaccugugca     1200

auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa acagacgugu     1260

cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag acuaaaugca     1320

cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu gauuacgucu     1380

caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua aauaagcaag     1440

aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac ccacucgugu     1500

ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc aaccagagcc     1560

uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc aaaucaacca     1620

caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc agucugaucg     1680

cuguaggccu ucuguuguac ugcaaggcca ggucuacacc cgugacgcuc agcaaggacc     1740

agcuguccgg gauaaacaau aucgcuuuuu caaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1255
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1255
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug aacaacgcca      420

agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc uuccugcugg      480

gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac cuggagggcg      540

aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug agccugagca      600

acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc gacaagcagc      660

ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc gugaucgagu      720

uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug aacgccggcg      780

ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc cugaucaacg      840

acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag aucgugagac      900

agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac guggugcagc      960

ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc ccccugugca     1020

ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga ggcugguacu     1080

gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag gugcagagca     1140

acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug aaccugugca     1200

acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag accgacguga     1260

gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag accaagugca     1320

ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac ccccuggugu     1500

uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc aagagcacca     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug agccugaucg     1680

ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug agcaaggacc     1740

agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1256
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1256
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug aauaacgcca      420

agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg uuucuccugg      480

gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac cuggaaggag      540

aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug ucccugagca      600

acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu gauaagcaac      660

ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc gucauugagu      720

uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu aaugccggcg      780

ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu cucaucaaug      840

acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag aucgugcggc      900

agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac gugguccaac      960

ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu ccccuuugua     1020

caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga ggcugguauu     1080

gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa gugcagagca     1140

accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug aaucugugca     1200

augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa acggacgugu     1260

ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag acaaaaugca     1320

ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu gauuacguca     1380

gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc aauaagcaag     1440

aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac ccccuggugu     1500

ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu aaccagagcc     1560

ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc aaaagcacca     1620

caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc ucucugaucg     1680

cggucgggcu gcuccuguac ugcaaggccc gguccacccc cgugacgcuu agcaaggacc     1740

agcugucugg aauuaacaau aucgcuuuuu ccaacugagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1257
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1257
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaau       60

uauuaauccu caaagcgaac gcuauuacua ccauucuaac agcagucaca uucugcuucg      120

ccucaggcca aaacauuaca gaagaauuuu accaaucaac augcucugcc guaucaaaag      180

gcuaccuauc cgcccuacga acaggcuggu acacaagcgu aauaacaauc gaacuaucaa      240

acauaaaaga aaacaaaugc aacgguacag acgccaaagu uaaacuaaua aaacaagaac      300

ucgauaaaua caaaaacgca guaacagaau uacaacuacu aaugcaauca acaccugcaa      360

caaacaauag agccaggaga gaauuaccuc gauucaugaa uuacacacuc aauaacgcaa      420

aaaaaaccaa cguuacacua ucaaaaaaaa gaaaacgacg auucuuagga uuccuacucg      480

gagucggauc agcaauagca ucuggcguug caguaugcaa aguauuacac uuagaaggug      540

aagucaauaa aauaaaaagc gcgcuacuaa guacaaacaa agcagucguc ucccuaucaa      600

acggagucuc aguccuaaca uucaaaguac ucgaccuaaa aaauuacaua gauaaacaac      660

uacuuccaau auuaaacaaa caauccugua gcaucagcaa uauagaaaca guaauagaau      720

uucaacaaaa aaacaaccga uuauuagaaa ucacucgaga auuuuccgua aacgccgggg      780

uaacaacucc agucucaacc uacaugcuaa ccaauucaga acuauugagc uuaauaaacg      840

acaugccaau aaccaacgac caaaaaaaac uaaugucuaa caauguucaa aucgucagac      900

aacaaaguua caguauaaug uguauaauca aagaagaagu ccuagcauac guaguccaac      960

ucccacuaua uggaguuauc gacacaccau guuggaaauu acacaccuca ccauuaugca     1020

caaccaauac aaaagaagga ucaaacauau gccuuacacg gacagaccgc ggaugguauu     1080

gugacaacgc uggcucaguc uccuuuuucc cacaagcaga aacaugcaaa guacaaucaa     1140

acagagucuu uugcgauacc augaacucac uuacauuacc aagcgaagua aaucuuugua     1200

acgucgacau cuucaauccu aaauaugacu gcaaaaucau gaccucaaaa acagacguua     1260

gcucuucagu aaucacuagc uuaggagcaa ucguaucaug cuacggcaaa acaaaaugua     1320

cagcaucaaa uaaaaacaga ggaaucauaa aaacauuuuc aaacggaugc gauuauguaa     1380

gcaacaaagg aguagauacu guaagcguag gaaacacauu guacuaugua aacaaacaag     1440

aaggaaaauc acucuaugua aaaggagaac cuauaaucaa uuucuacgau ccauuagugu     1500

ucccaucaga ugaauuugac gccucaauau cacaaguuaa ugaaaaaaua aaucaaucgc     1560

uagcauucau acguaaauca gaugaauuac uacauaacgu aaacgcaggc aaauccacaa     1620

caaauaucau gaucacaaca auuauaauag uaauaauagu aauacuacua ucacuaauag     1680

ccguaggacu ccuacuauac ugcaaagcaa gaucuacucc aguaacccuc ucaaaagauc     1740

aacuaagcgg aauuaauaac aucgcauuca gcaacuaagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1258
<211>  2107
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1258
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacuuauccu caaagccaac gccaucacca ccauccucac agcaguaacc uuuugcuucg      120

ccucaggcca aaauaucaca gaagaauuuu accagaguac cugcuccgcc guauccaaag      180

gauaccucag cgcgcuccgc accggcuggu acacuucagu aaucacaauc gaacuaucca      240

acaucaaaga aaacaaaugc aacggcaccg acgcgaaagu caaacucauc aaacaagaac      300

uagacaaaua caaaaaugcc guaacagaac uacaacuguu aaugcagagc acacccgcca      360

ccaacaaccg cgcccgccgg gaacuccccc gauucaugaa cuacacacuc aacaacgcca      420

aaaagacgaa cgucacccuc agcaagaaac gaaaacgcag auuccucggu uuccuacuag      480

gcguaggcuc agcaauagcc uccggaguag ccgucugcaa aguccugcac uuagaaggcg      540

aagucaacaa aaucaaaucc gcccuacucu ccacgaacaa agccgucguc ucccugucca      600

acggugucuc cguuuuaacc uucaaaguuc uggaccucaa aaacuacaua gacaaacagc      660

uucuccccau ccucaacaaa caauccugua gcaucuccaa caucgaaacc gucauagaau      720

uucaacagaa aaacaacaga cugcucgaaa ucacccgcga guucuccguc aacgccggcg      780

ucacgacucc cgucuccacc uauaugcuca cgaacucgga acuccuuucc cuaaucaacg      840

acaugccgau caccaacgac caaaagaaac ucaugucaaa caacguacaa auuguccgcc      900

aacaaucaua cuccaucaug ugcauaauua aagaagaagu ccucgcauac guaguccaac      960

ucccccucua cggcgucauc gacacccccu gcuggaaacu ccacaccucc ccacucugca     1020

caaccaacac caaagaaggc ucaaacauau gccuaacgcg caccgaucgc gguugguacu     1080

gcgacaacgc cgguuccguc agcuucuucc cccaagcaga gacaugcaaa guccaaucaa     1140

accgcgucuu cugcgacacc augaacucac uaacccuucc aagcgaaguc aaccucugca     1200

acguugacau cuucaacccc aaauacgacu guaaaaucau gaccuccaag accgacguau     1260

ccucuuccgu caucacaucc cuaggcgcua ucguauccug cuaugguaaa accaaaugca     1320

ccgccuccaa caaaaaccgc ggcaucauca agacauuuuc caacggcugc gacuacguga     1380

gcaacaaagg cgucgacacc gucuccguag gcaacacccu cuacuaugua aacaaacaag     1440

agggcaaauc acucuacguc aaaggggaac ccaucaucaa cuucuacgac ccgcucguau     1500

uccccagcga ugaguucgac gccuccaucu cccaggucaa cgaaaagaua aaccaaucac     1560

ucgcauucau ucguaaaucc gacgaacucc uacacaacgu gaaugcaggc aaaucgacca     1620

cuaacaucau gaucaccacc aucaucaucg ucaucauagu cauccuccug ucccuuaucg     1680

ccgucggucu uuuauuauac ugcaaagccc gcagcacccc cgucacccuc ucuaaggacc     1740

aacucagcgg caucaauaac aucgcauucu cuaacuaagg acuagugcau cacauuuaaa     1800

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1860

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1920

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2100

cagaauu                                                               2107


<210>  1259
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1) R6808

<400>  1259
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccaacaac cgcgcccggc gcgagcugcc ccgguucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcgcaagcgg      420

cgcuuccugg gcuuccuccu gggggugggc uccgccaucg cgagcggcgu cgccgugugc      480

aaggugcugc accucgaggg ggaggucaac aagaucaaga gcgcccugcu guccaccaac      540

aaggccgugg ugagccucuc caacggcguc agcgugcuga ccuucaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      660

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      720

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      780

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      840

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      900

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      960

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg     1020

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1080

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1140

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1260

ugcuacggca agacgaagug caccgccagc aacaagaacc gggggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1440

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1560

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1620

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1680

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1260
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt1)

<400>  1260
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccaacaac cgggcccgcc gggagcugcc gcgcuucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcggaagcgc      420

cgguuccugg gcuuccuccu gggggugggc uccgcgaucg ccagcggcgu cgccgugugc      480

aaggugcugc accucgaggg ggaggucaac aagaucaagu ccgcccugcu gagcaccaac      540

aaggccgugg ugucccucag caacggcguc uccgugcuga ccuucaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc auccucaaca agcagagcug cuccaucagc      660

aacaucgaga cggucaucga guuccagcag aagaacaacc gccugcugga gaucacccgg      720

gaguucuccg ugaacgcggg ggugaccacc cccgucagca cguacaugcu caccaacagc      780

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      840

aacaacgugc agaucgugcg ccagcagucc uacagcauca ugugcaucau caaggaggag      900

guccuggccu acguggugca gcucccgcug uacggcguca ucgacacccc cugcuggaag      960

cugcacacga gcccccucug caccaccaac accaaggagg ggagcaacau cugccugacg     1020

cggaccgacc gcggcuggua cugcgacaac gccggcuccg ugagcuucuu cccccaggcc     1080

gagaccugca agguccaguc caaccgggug uucugcgaca ccaugaacag ccugacgcuc     1140

ccguccgagg ugaaccugug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccagca agaccgacgu guccagcucc gugaucacca gccugggggc caucgucucc     1260

ugcuacggca agacgaagug caccgcgagc aacaagaacc gcgggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgucagcgu ggggaacacc     1380

cucuacuacg ugaacaagca ggagggcaag ucccuguacg ucaaggggga gcccaucauc     1440

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccaggug     1500

aacgagaaga ucaaccaguc ccucgccuuc auccggaagu ccgacgagcu gcugcacaac     1560

gucaacgccg gcaaguccac gaccaacauc augaucacca ccaucaucau cgugaucauc     1620

gugauccugc ucagccugau cgccgucggg cugcuccugu acugcaaggc gcgcuccacg     1680

cccgugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1261
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt2)

<400>  1261
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccaacaac cgcgcccgcc gcgagcuccc ccgcuucaug      360

aacuacaccc ucaacaacgc caagaagacc aacgucaccc ucuccaagaa gcgcaagcgc      420

cgcuuccucg gcuuccuccu cggcgucggc uccgccaucg ccuccggcgu cgccgucugc      480

aagguccucc accucgaggg cgaggucaac aagaucaagu ccgcccuccu cuccaccaac      540

aaggccgucg ucucccucuc caacggcguc uccguccuca ccuucaaggu ccucgaccuc      600

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      660

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      720

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      780

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      840

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      900

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      960

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc     1020

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1080

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1140

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1260

ugcuacggca agaccaagug caccgccucc aacaagaacc gcggcaucau caagaccuuc     1320

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1380

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1440

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1500

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1560

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1620

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1680

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1262
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt3)

<400>  1262
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccaacaau agggcucggc gcgaguugcc ucgauuuaug      360

aacuacacgc ucaauaacgc aaagaaaacu aaugugaccc ugucgaagaa acguaagaga      420

agguuccugg gcuuucucuu aggggucgga ucagccauag cuagcggcgu ggccguuugu      480

aaggugcugc accuugaagg ugaggucaac aaaaucaaga gugcguugcu guccacaaau      540

aaagcagugg uaucucuaag caacgggguu uccgugcuca cuuucaaggu ccuggaccuu      600

aaaaauuaua uugauaagca acuguugcca auccucaaca aacagucaug caguauuagc      660

aacaucgaaa ccgugauaga guuucagcag aagaauaacc ggcuguuaga gauuacacgc      720

gaguucucug ugaaugccgg agucaccacg ccgguuucca cuuacaugcu gacaaacuca      780

gaacuccuua gccugaucaa ugacaugccc auuaccaacg aucaaaagaa auugaugagu      840

aauaacgugc agaucguaag acagcagucu uauuccauca uguguauuau aaaggaagag      900

gugcuagcuu acgucgugca acugccucuc uacggcguua ucgacacucc augcuggaaa      960

cugcauacaa gcccccuuug uaccacgaau accaaggaag gcucgaacau uugccugaca     1020

aggacugauc ggggguggua uugugacaau gccggaucug uguccuuuuu cccucaggca     1080

gagaccugca aaguccaguc aaaccgcgug uuuugugaua caaugaauag uuugacucuc     1140

ccaagcgagg uaaaccugug caauguugac aucuucaacc ccaaguacga uugcaagaua     1200

augaccucca aaacagacgu gucuagcuca gucauuacca guuuaggugc uaucgugucc     1260

uguuauggca agacuaaaug cacggccagc aacaagaauc gagggaucau uaaaacauuu     1320

ucuaacggau gugauuacgu cucaaauaag ggcguggaca ccguuagugu ggguaacacu     1380

cuguauuacg uaaauaagca agaagggaaa agccuauaug ucaagggaga gccuaucauu     1440

aacuucuacg acccacucgu guucccgucc gaugaauuug acgcgucuau aucgcagguu     1500

aaugagaaaa ucaaccagag ccuggccuuc auuagaaagu ccgaugaacu uuugcacaau     1560

gugaacgcag gcaaaucaac cacaaauauc augaucacca cuauuauaau cgucauuauc     1620

gugauucugc ucagucugau cgcuguaggc cuucuguugu acugcaaggc caggucuaca     1680

cccgugacgc ucagcaagga ccagcugucc gggauaaaca auaucgcuuu uucaaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1263
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt4)

<400>  1263
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccaacaac agagccagaa gagagcugcc cagauucaug      360

aacuacaccc ugaacaacgc caagaagacc aacgugaccc ugagcaagaa gagaaagaga      420

agauuccugg gcuuccugcu gggcgugggc agcgccaucg ccagcggcgu ggccgugugc      480

aaggugcugc accuggaggg cgaggugaac aagaucaaga gcgcccugcu gagcaccaac      540

aaggccgugg ugagccugag caacggcgug agcgugcuga ccuucaaggu gcuggaccug      600

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      660

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      720

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      780

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      840

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      900

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      960

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc     1020

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1080

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1140

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1200

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1260

ugcuacggca agaccaagug caccgccagc aacaagaaca gaggcaucau caagaccuuc     1320

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1440

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1560

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1620

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1680

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1264
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt5)

<400>  1264
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacaaacaau cgggcucgca gagagcuccc ucgguuuaug      360

aacuacaccc ugaauaacgc caagaaaaca aaugucaccc uuucuaagaa acgcaagaga      420

cgguuccugg gguuucuccu gggagugggc agcgcgauug ccuccggggu ugcugugugu      480

aagguccuuc accuggaagg agaggugaac aaaaucaaga gcgcccuccu gucuacgaau      540

aaagcuguug ugucccugag caacggcguc ucugugcuca cauucaaggu gcuggaccuu      600

aaaaauuaua uugauaagca acugcucccg auccugaaca aacaguccug cagcauuucu      660

aacaucgaaa ccgucauuga guuucagcag aagaauaacc gccuucugga gaucacaaga      720

gaauuuuccg uuaaugccgg cgugaccacc cccgugagca cauacaugcu cacgaacucc      780

gagcugcugu cucucaucaa ugacaugccu auuaccaacg aucaaaagaa acugaugagc      840

aauaacgucc agaucgugcg gcagcagucc uauagcauua uguguaucau uaaggaagag      900

guucuugcgu acguggucca acugccccuc uacgggguga ucgacacacc uugcuggaaa      960

cugcauaccu cuccccuuug uacaaccaau acgaaggaag gauccaacau cugccugaca     1020

cgcaccgaua gaggcuggua uugugacaau gccgggagcg uuucuuucuu cccucaggcu     1080

gagaccugca aagugcagag caaccggguc uuuugugaua caaugaacuc ccucacccug     1140

ccgucugagg ugaaucugug caaugucgac auuuucaacc ccaaguacga uugcaagauc     1200

augacaagca aaacggacgu guccagcucu guuauuaccu cccucggagc caucgugagc     1260

uguuauggca agacaaaaug caccgcuucu aacaagaauc gcgggauuau caaaacauuu     1320

uccaacggau gugauuacgu cagcaauaag ggcguggaca ccguuuccgu gggcaacacg     1380

cuguauuacg ucaauaagca agaagggaaa ucucuuuaug ugaagggaga gccuaucauu     1440

aacuucuacg acccccuggu guucccuagc gaugaauuug acgccuccau cucucagguu     1500

aaugagaaaa uuaaccagag ccucgccuuc aucagaaagu ccgaugaacu gcugcacaau     1560

gucaacgcug gcaaaagcac cacaaauauu augaucacca caauuaucau cgugauuauc     1620

gugauucuuc ucucucugau cgcggucggg cugcuccugu acugcaaggc ccgguccacc     1680

cccgugacgc uuagcaagga ccagcugucu ggaauuaaca auaucgcuuu uuccaacuga     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1265
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt6)

<400>  1265
gggagaaagc uuaccaugga auuauuaauc cucaaagcga acgcuauuac uaccauucua       60

acagcaguca cauucugcuu cgccucaggc caaaacauua cagaagaauu uuaccaauca      120

acaugcucug ccguaucaaa aggcuaccua uccgcccuac gaacaggcug guacacaagc      180

guaauaacaa ucgaacuauc aaacauaaaa gaaaacaaau gcaacgguac agacgccaaa      240

guuaaacuaa uaaaacaaga acucgauaaa uacaaaaacg caguaacaga auuacaacua      300

cuaaugcaau caacaccugc aacaaacaau agagccagga gagaauuacc ucgauucaug      360

aauuacacac ucaauaacgc aaaaaaaacc aacguuacac uaucaaaaaa aagaaaacga      420

cgauucuuag gauuccuacu cggagucgga ucagcaauag caucuggcgu ugcaguaugc      480

aaaguauuac acuuagaagg ugaagucaau aaaauaaaaa gcgcgcuacu aaguacaaac      540

aaagcagucg ucucccuauc aaacggaguc ucaguccuaa cauucaaagu acucgaccua      600

aaaaauuaca uagauaaaca acuacuucca auauuaaaca aacaauccug uagcaucagc      660

aauauagaaa caguaauaga auuucaacaa aaaaacaacc gauuauuaga aaucacucga      720

gaauuuuccg uaaacgccgg gguaacaacu ccagucucaa ccuacaugcu aaccaauuca      780

gaacuauuga gcuuaauaaa cgacaugcca auaaccaacg accaaaaaaa acuaaugucu      840

aacaauguuc aaaucgucag acaacaaagu uacaguauaa uguguauaau caaagaagaa      900

guccuagcau acguagucca acucccacua uauggaguua ucgacacacc auguuggaaa      960

uuacacaccu caccauuaug cacaaccaau acaaaagaag gaucaaacau augccuuaca     1020

cggacagacc gcggauggua uugugacaac gcuggcucag ucuccuuuuu cccacaagca     1080

gaaacaugca aaguacaauc aaacagaguc uuuugcgaua ccaugaacuc acuuacauua     1140

ccaagcgaag uaaaucuuug uaacgucgac aucuucaauc cuaaauauga cugcaaaauc     1200

augaccucaa aaacagacgu uagcucuuca guaaucacua gcuuaggagc aaucguauca     1260

ugcuacggca aaacaaaaug uacagcauca aauaaaaaca gaggaaucau aaaaacauuu     1320

ucaaacggau gcgauuaugu aagcaacaaa ggaguagaua cuguaagcgu aggaaacaca     1380

uuguacuaug uaaacaaaca agaaggaaaa ucacucuaug uaaaaggaga accuauaauc     1440

aauuucuacg auccauuagu guucccauca gaugaauuug acgccucaau aucacaaguu     1500

aaugaaaaaa uaaaucaauc gcuagcauuc auacguaaau cagaugaauu acuacauaac     1560

guaaacgcag gcaaauccac aacaaauauc augaucacaa caauuauaau aguaauaaua     1620

guaauacuac uaucacuaau agccguagga cuccuacuau acugcaaagc aagaucuacu     1680

ccaguaaccc ucucaaaaga ucaacuaagc ggaauuaaua acaucgcauu cagcaacuaa     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1266
<211>  1942
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F0_DSCav1 (opt11)

<400>  1266
gggagaaagc uuaccaugga acuacuuauc cucaaagcca acgccaucac caccauccuc       60

acagcaguaa ccuuuugcuu cgccucaggc caaaauauca cagaagaauu uuaccagagu      120

accugcuccg ccguauccaa aggauaccuc agcgcgcucc gcaccggcug guacacuuca      180

guaaucacaa ucgaacuauc caacaucaaa gaaaacaaau gcaacggcac cgacgcgaaa      240

gucaaacuca ucaaacaaga acuagacaaa uacaaaaaug ccguaacaga acuacaacug      300

uuaaugcaga gcacacccgc caccaacaac cgcgcccgcc gggaacuccc ccgauucaug      360

aacuacacac ucaacaacgc caaaaagacg aacgucaccc ucagcaagaa acgaaaacgc      420

agauuccucg guuuccuacu aggcguaggc ucagcaauag ccuccggagu agccgucugc      480

aaaguccugc acuuagaagg cgaagucaac aaaaucaaau ccgcccuacu cuccacgaac      540

aaagccgucg ucucccuguc caacgguguc uccguuuuaa ccuucaaagu ucuggaccuc      600

aaaaacuaca uagacaaaca gcuucucccc auccucaaca aacaauccug uagcaucucc      660

aacaucgaaa ccgucauaga auuucaacag aaaaacaaca gacugcucga aaucacccgc      720

gaguucuccg ucaacgccgg cgucacgacu cccgucucca ccuauaugcu cacgaacucg      780

gaacuccuuu cccuaaucaa cgacaugccg aucaccaacg accaaaagaa acucauguca      840

aacaacguac aaauuguccg ccaacaauca uacuccauca ugugcauaau uaaagaagaa      900

guccucgcau acguagucca acucccccuc uacggcguca ucgacacccc cugcuggaaa      960

cuccacaccu ccccacucug cacaaccaac accaaagaag gcucaaacau augccuaacg     1020

cgcaccgauc gcgguuggua cugcgacaac gccgguuccg ucagcuucuu cccccaagca     1080

gagacaugca aaguccaauc aaaccgcguc uucugcgaca ccaugaacuc acuaacccuu     1140

ccaagcgaag ucaaccucug caacguugac aucuucaacc ccaaauacga cuguaaaauc     1200

augaccucca agaccgacgu auccucuucc gucaucacau cccuaggcgc uaucguaucc     1260

ugcuauggua aaaccaaaug caccgccucc aacaaaaacc gcggcaucau caagacauuu     1320

uccaacggcu gcgacuacgu gagcaacaaa ggcgucgaca ccgucuccgu aggcaacacc     1380

cucuacuaug uaaacaaaca agagggcaaa ucacucuacg ucaaagggga acccaucauc     1440

aacuucuacg acccgcucgu auuccccagc gaugaguucg acgccuccau cucccagguc     1500

aacgaaaaga uaaaccaauc acucgcauuc auucguaaau ccgacgaacu ccuacacaac     1560

gugaaugcag gcaaaucgac cacuaacauc augaucacca ccaucaucau cgucaucaua     1620

gucauccucc ugucccuuau cgccgucggu cuuuuauuau acugcaaagc ccgcagcacc     1680

cccgucaccc ucucuaagga ccaacucagc ggcaucaaua acaucgcauu cucuaacuaa     1740

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1800

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1920

ucuuuucaga gccaccagaa uu                                              1942


<210>  1267
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1

<400>  1267

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Cys Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Phe Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Cys Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  1268
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1

<400>  1268
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaacca acaaccgcgc ccggcgcgag cugccccggu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgca agcggcgcuu ccugggcuuc      420

cuccuggggg ugggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu ga                        1662


<210>  1269
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1

<400>  1269
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccacca acaaccgggc ccgccgggag cugccgcgcu ucaugaacua cacccucaac      360

aacgccaaga agacgaacgu gacccugagc aagaagcgga agcgccgguu ccugggcuuc      420

cuccuggggg ugggcuccgc gaucgccagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caaguccgcc cugcugagca ccaacaaggc cguggugucc      540

cucagcaacg gcgucuccgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu caacaagcag agcugcucca ucagcaacau cgagacgguc      660

aucgaguucc agcagaagaa caaccgccug cuggagauca cccgggaguu cuccgugaac      720

gcggggguga ccacccccgu cagcacguac augcucacca acagcgagcu gcugucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugcgccagc aguccuacag caucaugugc aucaucaagg aggagguccu ggccuacgug      900

gugcagcucc cgcuguacgg cgucaucgac acccccugcu ggaagcugca cacgagcccc      960

cucugcacca ccaacaccaa ggaggggagc aacaucugcc ugacgcggac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc ggguguucug cgacaccaug aacagccuga cgcucccguc cgaggugaac     1140

cugugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgugau caccagccug ggggccaucg ucuccugcua cggcaagacg     1260

aagugcaccg cgagcaacaa gaaccgcggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccguc agcgugggga acacccucua cuacgugaac     1380

aagcaggagg gcaagucccu guacgucaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggugaacga gaagaucaac     1500

cagucccucg ccuucauccg gaaguccgac gagcugcugc acaacgucaa cgccggcaag     1560

uccacgacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcucagc     1620

cugaucgccg ucgggcugcu ccuguacugc aaggcgcgcu ga                        1662


<210>  1270
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1

<400>  1270
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccacca acaaccgcgc ccgccgcgag cucccccgcu ucaugaacua cacccucaac      360

aacgccaaga agaccaacgu cacccucucc aagaagcgca agcgccgcuu ccucggcuuc      420

cuccucggcg ucggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ga                        1662


<210>  1271
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1

<400>  1271
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccacca acaauagggc ucggcgcgag uugccucgau uuaugaacua cacgcucaau      360

aacgcaaaga aaacuaaugu gacccugucg aagaaacgua agagaagguu ccugggcuuu      420

cucuuagggg ucggaucagc cauagcuagc ggcguggccg uuuguaaggu gcugcaccuu      480

gaaggugagg ucaacaaaau caagagugcg uugcugucca caaauaaagc agugguaucu      540

cuaagcaacg ggguuuccgu gcucacuuuc aagguccugg accuuaaaaa uuauauugau      600

aagcaacugu ugccaauccu caacaaacag ucaugcagua uuagcaacau cgaaaccgug      660

auagaguuuc agcagaagaa uaaccggcug uuagagauua cacgcgaguu cucugugaau      720

gccggaguca ccacgccggu uuccacuuac augcugacaa acucagaacu ccuuagccug      780

aucaaugaca ugcccauuac caacgaucaa aagaaauuga ugaguaauaa cgugcagauc      840

guaagacagc agucuuauuc caucaugugu auuauaaagg aagaggugcu agcuuacguc      900

gugcaacugc cucucuacgg cguuaucgac acuccaugcu ggaaacugca uacaagcccc      960

cuuuguacca cgaauaccaa ggaaggcucg aacauuugcc ugacaaggac ugaucggggg     1020

ugguauugug acaaugccgg aucugugucc uuuuucccuc aggcagagac cugcaaaguc     1080

cagucaaacc gcguguuuug ugauacaaug aauaguuuga cucucccaag cgagguaaac     1140

cugugcaaug uugacaucuu caaccccaag uacgauugca agauaaugac cuccaaaaca     1200

gacgugucua gcucagucau uaccaguuua ggugcuaucg uguccuguua uggcaagacu     1260

aaaugcacgg ccagcaacaa gaaucgaggg aucauuaaaa cauuuucuaa cggaugugau     1320

uacgucucaa auaagggcgu ggacaccguu agugugggua acacucugua uuacguaaau     1380

aagcaagaag ggaaaagccu auaugucaag ggagagccua ucauuaacuu cuacgaccca     1440

cucguguucc cguccgauga auuugacgcg ucuauaucgc agguuaauga gaaaaucaac     1500

cagagccugg ccuucauuag aaaguccgau gaacuuuugc acaaugugaa cgcaggcaaa     1560

ucaaccacaa auaucaugau caccacuauu auaaucguca uuaucgugau ucugcucagu     1620

cugaucgcug uaggccuucu guuguacugc aaggccaggu ga                        1662


<210>  1272
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1

<400>  1272
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccacca acaacagagc cagaagagag cugcccagau ucaugaacua cacccugaac      360

aacgccaaga agaccaacgu gacccugagc aagaagagaa agagaagauu ccugggcuuc      420

cugcugggcg ugggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau ga                        1662


<210>  1273
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1

<400>  1273
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacaa acaaucgggc ucgcagagag cucccucggu uuaugaacua cacccugaau      360

aacgccaaga aaacaaaugu cacccuuucu aagaaacgca agagacgguu ccugggguuu      420

cuccugggag ugggcagcgc gauugccucc gggguugcug uguguaaggu ccuucaccug      480

gaaggagagg ugaacaaaau caagagcgcc cuccugucua cgaauaaagc uguugugucc      540

cugagcaacg gcgucucugu gcucacauuc aaggugcugg accuuaaaaa uuauauugau      600

aagcaacugc ucccgauccu gaacaaacag uccugcagca uuucuaacau cgaaaccguc      660

auugaguuuc agcagaagaa uaaccgccuu cuggagauca caagagaauu uuccguuaau      720

gccggcguga ccacccccgu gagcacauac augcucacga acuccgagcu gcugucucuc      780

aucaaugaca ugccuauuac caacgaucaa aagaaacuga ugagcaauaa cguccagauc      840

gugcggcagc aguccuauag cauuaugugu aucauuaagg aagagguucu ugcguacgug      900

guccaacugc cccucuacgg ggugaucgac acaccuugcu ggaaacugca uaccucuccc      960

cuuuguacaa ccaauacgaa ggaaggaucc aacaucugcc ugacacgcac cgauagaggc     1020

ugguauugug acaaugccgg gagcguuucu uucuucccuc aggcugagac cugcaaagug     1080

cagagcaacc gggucuuuug ugauacaaug aacucccuca cccugccguc ugaggugaau     1140

cugugcaaug ucgacauuuu caaccccaag uacgauugca agaucaugac aagcaaaacg     1200

gacgugucca gcucuguuau uaccucccuc ggagccaucg ugagcuguua uggcaagaca     1260

aaaugcaccg cuucuaacaa gaaucgcggg auuaucaaaa cauuuuccaa cggaugugau     1320

uacgucagca auaagggcgu ggacaccguu uccgugggca acacgcugua uuacgucaau     1380

aagcaagaag ggaaaucucu uuaugugaag ggagagccua ucauuaacuu cuacgacccc     1440

cugguguucc cuagcgauga auuugacgcc uccaucucuc agguuaauga gaaaauuaac     1500

cagagccucg ccuucaucag aaaguccgau gaacugcugc acaaugucaa cgcuggcaaa     1560

agcaccacaa auauuaugau caccacaauu aucaucguga uuaucgugau ucuucucucu     1620

cugaucgcgg ucgggcugcu ccuguacugc aaggcccggu ga                        1662


<210>  1274
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1

<400>  1274
auggaacuau uaauauuaaa agcaaaugcu auuaccacaa uacuuacugc uguaaccuuc       60

ugcuuugccu cuggccaaaa cauaacagaa gaauuuuauc aaucaacuug cuccgcugua      120

agcaaaggcu accuaucagc auuacgcacc ggcugguaca caucaguaau aacaauagaa      180

cuauccaaca uaaaagaaaa uaaaugcaac ggaacagacg caaaaguaaa auuaauaaaa      240

caagaacucg acaaauacaa aaacgcagua acagaauuac aacuacuaau gcaaaguacu      300

ccagccacca acaacagagc aagaagagaa uuaccacgau uuaugaacua cacacuaaac      360

aaugcaaaaa aaacaaacgu aacacuauca aaaaaacgua aacgcagauu cuuaggcuuc      420

cuccuaggug uaggcucagc aaucgccuca ggaguggcag uuuguaaagu acuacaccua      480

gaaggagaag uaaacaaaau caaaucugcc cuuuuaucga caaacaaagc aguaguaucg      540

uuauccaaug gagucucagu auugacauuc aaaguauuag accuaaaaaa uuauauagau      600

aaacaacucu uaccuaucuu aaauaaacaa agcugcucaa uaaguaacau agaaaccgua      660

auagaauuuc aacaaaaaaa caauagacuc cuugagauca cucgagaauu uucaguaaac      720

gcagguguaa caacaccagu aagcacauac augcuaacaa auagugaacu auuaucucua      780

auuaacgaua ugcccauaac caacgaucaa aaaaaacuca ugaguaacaa cguacaaaua      840

guaagacaac aauccuauag cauaaugugc auuauaaaag aagaaguacu agcauaugua      900

guccaacuac cacuauacgg cguaauagac acaccaugcu ggaaacuaca caccucaccc      960

cuaugcacaa caaauacaaa agaaggauca aacauaugcu uaaccaggac agacagaggc     1020

ugguacugcg auaacgcagg aucuguuuca uucuuccccc aagcagaaac augcaaagua     1080

caaucaaaca gaguauuuug ugauaccaug aacucacuca cauuaccauc cgaagucaac     1140

cucugcaacg uagacauauu caaccccaaa uacgacugca aaauaaugac cucaaaaaca     1200

gauguaucau caucaguaau cacaucacua ggagcuaucg uaucuuguua uggaaaaaca     1260

aaaugcacag cauccaacaa aaacagagga auuaucaaaa cauucucaaa uggaugugac     1320

uauguaucaa acaaaggagu agacaccgua agcguaggca auacacuaua uuacguaaau     1380

aaacaagaag gaaaaucacu auacguaaaa ggugaaccaa uaauaaacuu cuaugacccc     1440

cuaguauucc caucagauga auuugacgca agcauaucac aagucaacga aaaaauaaac     1500

caaucacugg cauucauucg caaaucagau gaacuucucc acaacguaaa cgcugguaaa     1560

agcacuacaa acauaaugau aacaacaauc aucauuguca uaauaguuau ucuauuauca     1620

cuaaucgcag uaggauuacu acuauacugu aaagcgaggu aa                        1662


<210>  1275
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1

<400>  1275
auggagcugc ucauccugaa ggccaacgcc aucaccacaa uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgaacc ggcugguaca ccuccgugau caccaucgag      180

cugucaaaca ucaaggagaa caagugcaac gggaccgaug ccaagguuaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacu      300

ccggcaacca acaaccgcgc caggcgcgag cugccccggu ucaugaacua cacccucaac      360

aacgccaaga agacgaaugu gacccugagc aagaagcgca agcggcgcuu ccugggcuuc      420

cuccuagggg ugggcuccgc caucgcgagc ggcgucgccg ugugcaaggu guugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cgugguaagc      540

cucuccaacg gcgucagcgu ucugaccuuc aaggugcugg accucaagaa cuauaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucucaaacau cgaaacggug      660

auugaguucc agcagaagaa caaccggcuc cuggaaauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccuaucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aagaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacaa ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccuc ugagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagaca     1200

gacgugagcu ccagcgugau cacaucccug ggggccaucg ucagcugcua cggcaagacu     1260

aaguguacug ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacguuaau     1380

aagcaggagg gcaagagccu cuacgugaaa ggggagccca ucauuaacuu cuacgaccca     1440

cugguuuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguga ucaucgugau ucugcugucc     1620

cucaucgccg uggggcugcu gcuuuacugc aaggcccggu ga                        1662


<210>  1276
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1276
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1277
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1277
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1278
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1278
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1279
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1279
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1280
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1280
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1281
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1281
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1282
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1282
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaaugcuauu accacaauac      120

uuacugcugu aaccuucugc uuugccucug gccaaaacau aacagaagaa uuuuaucaau      180

caacuugcuc cgcuguaagc aaaggcuacc uaucagcauu acgcaccggc ugguacacau      240

caguaauaac aauagaacua uccaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguaaaauu aauaaaacaa gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aaguacucca gccaccaaca acagagcaag aagagaauua ccacgauuua      420

ugaacuacac acuaaacaau gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac      480

gcagauucuu aggcuuccuc cuagguguag gcucagcaau cgccucagga guggcaguuu      540

guaaaguacu acaccuagaa ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa      600

acaaagcagu aguaucguua uccaauggag ucucaguauu gacauucaaa guauuagacc      660

uaaaaaauua uauagauaaa caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa      720

guaacauaga aaccguaaua gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc      780

gagaauuuuc aguaaacgca gguguaacaa caccaguaag cacauacaug cuaacaaaua      840

gugaacuauu aucucuaauu aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga      900

guaacaacgu acaaauagua agacaacaau ccuauagcau aaugugcauu auaaaagaag      960

aaguacuagc auauguaguc caacuaccac uauacggcgu aauagacaca ccaugcugga     1020

aacuacacac cucaccccua ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa     1080

ccaggacaga cagaggcugg uacugcgaua acgcaggauc uguuucauuc uucccccaag     1140

cagaaacaug caaaguacaa ucaaacagag uauuuuguga uaccaugaac ucacucacau     1200

uaccauccga agucaaccuc ugcaacguag acauauucaa ccccaaauac gacugcaaaa     1260

uaaugaccuc aaaaacagau guaucaucau caguaaucac aucacuagga gcuaucguau     1320

cuuguuaugg aaaaacaaaa ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau     1380

ucucaaaugg augugacuau guaucaaaca aaggaguaga caccguaagc guaggcaaua     1440

cacuauauua cguaaauaaa caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa     1500

uaaacuucua ugacccccua guauucccau cagaugaauu ugacgcaagc auaucacaag     1560

ucaacgaaaa aauaaaccaa ucacuggcau ucauucgcaa aucagaugaa cuucuccaca     1620

acguaaacgc ugguaaaagc acuacaaaca uaaugauaac aacaaucauc auugucauaa     1680

uaguuauucu auuaucacua aucgcaguag gauuacuacu auacuguaaa gcgagguaag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1283
<211>  1938
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1283
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accacaaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgaaccggc ugguacaccu      240

ccgugaucac caucgagcug ucaaacauca aggagaacaa gugcaacggg accgaugcca      300

agguuaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccacuccg gcaaccaaca accgcgccag gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaaugugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cuaggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaagguguu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu gguaagccuc uccaacggcg ucagcguucu gaccuucaag gugcuggacc      660

ucaagaacua uaucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccaucu      720

caaacaucga aacggugauu gaguuccagc agaagaacaa ccggcuccug gaaaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu aucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggaag      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcacaacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccucuga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagacagac gugagcucca gcgugaucac aucccugggg gccaucguca     1320

gcugcuacgg caagacuaag uguacugcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cguuaauaag caggagggca agagccucua cgugaaaggg gagcccauca     1500

uuaacuucua cgacccacug guuuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauucu gcugucccuc aucgccgugg ggcugcugcu uuacugcaag gcccggugag     1740

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1800

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1920

uucagagcca ccagaauu                                                   1938


<210>  1284
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1284
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1285
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1285
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1286
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1286
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1287
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1287
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1288
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1288
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1289
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1289
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1290
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1290
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aaugcuauua ccacaauacu uacugcugua accuucugcu uugccucugg ccaaaacaua      180

acagaagaau uuuaucaauc aacuugcucc gcuguaagca aaggcuaccu aucagcauua      240

cgcaccggcu gguacacauc aguaauaaca auagaacuau ccaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguaaaauua auaaaacaag aacucgacaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa aguacuccag ccaccaacaa cagagcaaga      420

agagaauuac cacgauuuau gaacuacaca cuaaacaaug caaaaaaaac aaacguaaca      480

cuaucaaaaa aacguaaacg cagauucuua ggcuuccucc uagguguagg cucagcaauc      540

gccucaggag uggcaguuug uaaaguacua caccuagaag gagaaguaaa caaaaucaaa      600

ucugcccuuu uaucgacaaa caaagcagua guaucguuau ccaauggagu cucaguauug      660

acauucaaag uauuagaccu aaaaaauuau auagauaaac aacucuuacc uaucuuaaau      720

aaacaaagcu gcucaauaag uaacauagaa accguaauag aauuucaaca aaaaaacaau      780

agacuccuug agaucacucg agaauuuuca guaaacgcag guguaacaac accaguaagc      840

acauacaugc uaacaaauag ugaacuauua ucucuaauua acgauaugcc cauaaccaac      900

gaucaaaaaa aacucaugag uaacaacgua caaauaguaa gacaacaauc cuauagcaua      960

augugcauua uaaaagaaga aguacuagca uauguagucc aacuaccacu auacggcgua     1020

auagacacac caugcuggaa acuacacacc ucaccccuau gcacaacaaa uacaaaagaa     1080

ggaucaaaca uaugcuuaac caggacagac agaggcuggu acugcgauaa cgcaggaucu     1140

guuucauucu ucccccaagc agaaacaugc aaaguacaau caaacagagu auuuugugau     1200

accaugaacu cacucacauu accauccgaa gucaaccucu gcaacguaga cauauucaac     1260

cccaaauacg acugcaaaau aaugaccuca aaaacagaug uaucaucauc aguaaucaca     1320

ucacuaggag cuaucguauc uuguuaugga aaaacaaaau gcacagcauc caacaaaaac     1380

agaggaauua ucaaaacauu cucaaaugga ugugacuaug uaucaaacaa aggaguagac     1440

accguaagcg uaggcaauac acuauauuac guaaauaaac aagaaggaaa aucacuauac     1500

guaaaaggug aaccaauaau aaacuucuau gacccccuag uauucccauc agaugaauuu     1560

gacgcaagca uaucacaagu caacgaaaaa auaaaccaau cacuggcauu cauucgcaaa     1620

ucagaugaac uucuccacaa cguaaacgcu gguaaaagca cuacaaacau aaugauaaca     1680

acaaucauca uugucauaau aguuauucua uuaucacuaa ucgcaguagg auuacuacua     1740

uacuguaaag cgagguaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1291
<211>  1957
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1291
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccacaauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgaaccggcu gguacaccuc cgugaucacc aucgagcugu caaacaucaa ggagaacaag      300

ugcaacggga ccgaugccaa gguuaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacuccgg caaccaacaa ccgcgccagg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaaugugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uagggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caagguguug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug guaagccucu ccaacggcgu cagcguucug      660

accuucaagg ugcuggaccu caagaacuau aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucuc aaacaucgaa acggugauug aguuccagca gaagaacaac      780

cggcuccugg aaaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccua ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggaaga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcacaaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccucugag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagacagacg ugagcuccag cgugaucaca     1320

ucccuggggg ccaucgucag cugcuacggc aagacuaagu guacugccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac guuaauaagc aggagggcaa gagccucuac     1500

gugaaagggg agcccaucau uaacuucuac gacccacugg uuuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauucug cugucccuca ucgccguggg gcugcugcuu     1740

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1800

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1920

ccccccccca aaggcucuuu ucagagccac cagaauu                              1957


<210>  1292
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1292
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1293
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1293
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1294
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1294
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1295
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1295
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1296
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1296
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1297
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1297
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cggugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1298
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1298
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa ugcuauuacc acaauacuua cugcuguaac cuucugcuuu      240

gccucuggcc aaaacauaac agaagaauuu uaucaaucaa cuugcuccgc uguaagcaaa      300

ggcuaccuau cagcauuacg caccggcugg uacacaucag uaauaacaau agaacuaucc      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uaaaauuaau aaaacaagaa      420

cucgacaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaaag uacuccagcc      480

accaacaaca gagcaagaag agaauuacca cgauuuauga acuacacacu aaacaaugca      540

aaaaaaacaa acguaacacu aucaaaaaaa cguaaacgca gauucuuagg cuuccuccua      600

gguguaggcu cagcaaucgc cucaggagug gcaguuugua aaguacuaca ccuagaagga      660

gaaguaaaca aaaucaaauc ugcccuuuua ucgacaaaca aagcaguagu aucguuaucc      720

aauggagucu caguauugac auucaaagua uuagaccuaa aaaauuauau agauaaacaa      780

cucuuaccua ucuuaaauaa acaaagcugc ucaauaagua acauagaaac cguaauagaa      840

uuucaacaaa aaaacaauag acuccuugag aucacucgag aauuuucagu aaacgcaggu      900

guaacaacac caguaagcac auacaugcua acaaauagug aacuauuauc ucuaauuaac      960

gauaugccca uaaccaacga ucaaaaaaaa cucaugagua acaacguaca aauaguaaga     1020

caacaauccu auagcauaau gugcauuaua aaagaagaag uacuagcaua uguaguccaa     1080

cuaccacuau acggcguaau agacacacca ugcuggaaac uacacaccuc accccuaugc     1140

acaacaaaua caaaagaagg aucaaacaua ugcuuaacca ggacagacag aggcugguac     1200

ugcgauaacg caggaucugu uucauucuuc ccccaagcag aaacaugcaa aguacaauca     1260

aacagaguau uuugugauac caugaacuca cucacauuac cauccgaagu caaccucugc     1320

aacguagaca uauucaaccc caaauacgac ugcaaaauaa ugaccucaaa aacagaugua     1380

ucaucaucag uaaucacauc acuaggagcu aucguaucuu guuauggaaa aacaaaaugc     1440

acagcaucca acaaaaacag aggaauuauc aaaacauucu caaauggaug ugacuaugua     1500

ucaaacaaag gaguagacac cguaagcgua ggcaauacac uauauuacgu aaauaaacaa     1560

gaaggaaaau cacuauacgu aaaaggugaa ccaauaauaa acuucuauga cccccuagua     1620

uucccaucag augaauuuga cgcaagcaua ucacaaguca acgaaaaaau aaaccaauca     1680

cuggcauuca uucgcaaauc agaugaacuu cuccacaacg uaaacgcugg uaaaagcacu     1740

acaaacauaa ugauaacaac aaucaucauu gucauaauag uuauucuauu aucacuaauc     1800

gcaguaggau uacuacuaua cuguaaagcg agguaaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1299
<211>  2035
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1299
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc acaauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg aaccggcugg uacaccuccg ugaucaccau cgagcuguca      360

aacaucaagg agaacaagug caacgggacc gaugccaagg uuaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacuccggca      480

accaacaacc gcgccaggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga augugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccua      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca agguguugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu aagccucucc      720

aacggcguca gcguucugac cuucaaggug cuggaccuca agaacuauau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucucaa acaucgaaac ggugauugag      840

uuccagcaga agaacaaccg gcuccuggaa aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuauc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaagagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

acaaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccucugaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gacagacgug     1380

agcuccagcg ugaucacauc ccugggggcc aucgucagcu gcuacggcaa gacuaagugu     1440

acugccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu uaauaagcag     1560

gagggcaaga gccucuacgu gaaaggggag cccaucauua acuucuacga cccacugguu     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauucugcu gucccucauc     1800

gccguggggc ugcugcuuua cugcaaggcc cggugaggac uagucccugu ucccagagcc     1860

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1980

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          2035


<210>  1300
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1300
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1301
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1301
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1302
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1302
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1303
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1303
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1304
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1304
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1305
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1305
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc ggugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1306
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1306
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaau gcuauuacca caauacuuac ugcuguaacc      180

uucugcuuug ccucuggcca aaacauaaca gaagaauuuu aucaaucaac uugcuccgcu      240

guaagcaaag gcuaccuauc agcauuacgc accggcuggu acacaucagu aauaacaaua      300

gaacuaucca acauaaaaga aaauaaaugc aacggaacag acgcaaaagu aaaauuaaua      360

aaacaagaac ucgacaaaua caaaaacgca guaacagaau uacaacuacu aaugcaaagu      420

acuccagcca ccaacaacag agcaagaaga gaauuaccac gauuuaugaa cuacacacua      480

aacaaugcaa aaaaaacaaa cguaacacua ucaaaaaaac guaaacgcag auucuuaggc      540

uuccuccuag guguaggcuc agcaaucgcc ucaggagugg caguuuguaa aguacuacac      600

cuagaaggag aaguaaacaa aaucaaaucu gcccuuuuau cgacaaacaa agcaguagua      660

ucguuaucca auggagucuc aguauugaca uucaaaguau uagaccuaaa aaauuauaua      720

gauaaacaac ucuuaccuau cuuaaauaaa caaagcugcu caauaaguaa cauagaaacc      780

guaauagaau uucaacaaaa aaacaauaga cuccuugaga ucacucgaga auuuucagua      840

aacgcaggug uaacaacacc aguaagcaca uacaugcuaa caaauaguga acuauuaucu      900

cuaauuaacg auaugcccau aaccaacgau caaaaaaaac ucaugaguaa caacguacaa      960

auaguaagac aacaauccua uagcauaaug ugcauuauaa aagaagaagu acuagcauau     1020

guaguccaac uaccacuaua cggcguaaua gacacaccau gcuggaaacu acacaccuca     1080

ccccuaugca caacaaauac aaaagaagga ucaaacauau gcuuaaccag gacagacaga     1140

ggcugguacu gcgauaacgc aggaucuguu ucauucuucc cccaagcaga aacaugcaaa     1200

guacaaucaa acagaguauu uugugauacc augaacucac ucacauuacc auccgaaguc     1260

aaccucugca acguagacau auucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1320

acagauguau caucaucagu aaucacauca cuaggagcua ucguaucuug uuauggaaaa     1380

acaaaaugca cagcauccaa caaaaacaga ggaauuauca aaacauucuc aaauggaugu     1440

gacuauguau caaacaaagg aguagacacc guaagcguag gcaauacacu auauuacgua     1500

aauaaacaag aaggaaaauc acuauacgua aaaggugaac caauaauaaa cuucuaugac     1560

ccccuaguau ucccaucaga ugaauuugac gcaagcauau cacaagucaa cgaaaaaaua     1620

aaccaaucac uggcauucau ucgcaaauca gaugaacuuc uccacaacgu aaacgcuggu     1680

aaaagcacua caaacauaau gauaacaaca aucaucauug ucauaauagu uauucuauua     1740

ucacuaaucg caguaggauu acuacuauac uguaaagcga gguaaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1307
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1307
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca caauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcga accggcuggu acaccuccgu gaucaccauc      300

gagcugucaa acaucaagga gaacaagugc aacgggaccg augccaaggu uaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acuccggcaa ccaacaaccg cgccaggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa ugugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccuag gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa gguguugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggua      660

agccucucca acggcgucag cguucugacc uucaaggugc uggaccucaa gaacuauauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucucaaa caucgaaacg      780

gugauugagu uccagcagaa gaacaaccgg cuccuggaaa ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccuaucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaagaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca caaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cucugaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

acagacguga gcuccagcgu gaucacaucc cugggggcca ucgucagcug cuacggcaag     1380

acuaagugua cugccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacguu     1500

aauaagcagg agggcaagag ccucuacgug aaaggggagc ccaucauuaa cuucuacgac     1560

ccacugguuu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauucugcug     1740

ucccucaucg ccguggggcu gcugcuuuac ugcaaggccc ggugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  1308
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1308
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1309
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1309
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1310
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1310
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1311
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1311
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccaggug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1312
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1312
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1313
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1313
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccggug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1314
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1314
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaaugcua uuaccacaau acuuacugcu      120

guaaccuucu gcuuugccuc uggccaaaac auaacagaag aauuuuauca aucaacuugc      180

uccgcuguaa gcaaaggcua ccuaucagca uuacgcaccg gcugguacac aucaguaaua      240

acaauagaac uauccaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguaaaa      300

uuaauaaaac aagaacucga caaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaaguacuc cagccaccaa caacagagca agaagagaau uaccacgauu uaugaacuac      420

acacuaaaca augcaaaaaa aacaaacgua acacuaucaa aaaaacguaa acgcagauuc      480

uuaggcuucc uccuaggugu aggcucagca aucgccucag gaguggcagu uuguaaagua      540

cuacaccuag aaggagaagu aaacaaaauc aaaucugccc uuuuaucgac aaacaaagca      600

guaguaucgu uauccaaugg agucucagua uugacauuca aaguauuaga ccuaaaaaau      660

uauauagaua aacaacucuu accuaucuua aauaaacaaa gcugcucaau aaguaacaua      720

gaaaccguaa uagaauuuca acaaaaaaac aauagacucc uugagaucac ucgagaauuu      780

ucaguaaacg cagguguaac aacaccagua agcacauaca ugcuaacaaa uagugaacua      840

uuaucucuaa uuaacgauau gcccauaacc aacgaucaaa aaaaacucau gaguaacaac      900

guacaaauag uaagacaaca auccuauagc auaaugugca uuauaaaaga agaaguacua      960

gcauauguag uccaacuacc acuauacggc guaauagaca caccaugcug gaaacuacac     1020

accucacccc uaugcacaac aaauacaaaa gaaggaucaa acauaugcuu aaccaggaca     1080

gacagaggcu gguacugcga uaacgcagga ucuguuucau ucuuccccca agcagaaaca     1140

ugcaaaguac aaucaaacag aguauuuugu gauaccauga acucacucac auuaccaucc     1200

gaagucaacc ucugcaacgu agacauauuc aaccccaaau acgacugcaa aauaaugacc     1260

ucaaaaacag auguaucauc aucaguaauc acaucacuag gagcuaucgu aucuuguuau     1320

ggaaaaacaa aaugcacagc auccaacaaa aacagaggaa uuaucaaaac auucucaaau     1380

ggaugugacu auguaucaaa caaaggagua gacaccguaa gcguaggcaa uacacuauau     1440

uacguaaaua aacaagaagg aaaaucacua uacguaaaag gugaaccaau aauaaacuuc     1500

uaugaccccc uaguauuccc aucagaugaa uuugacgcaa gcauaucaca agucaacgaa     1560

aaaauaaacc aaucacuggc auucauucgc aaaucagaug aacuucucca caacguaaac     1620

gcugguaaaa gcacuacaaa cauaaugaua acaacaauca ucauugucau aauaguuauu     1680

cuauuaucac uaaucgcagu aggauuacua cuauacugua aagcgaggua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1315
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1315
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccacaau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgaaccg gcugguacac cuccgugauc      240

accaucgagc ugucaaacau caaggagaac aagugcaacg ggaccgaugc caagguuaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccacuc cggcaaccaa caaccgcgcc aggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaaugug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccuaggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

uugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

gugguaagcc ucuccaacgg cgucagcguu cugaccuuca aggugcugga ccucaagaac      660

uauaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cucaaacauc      720

gaaacgguga uugaguucca gcagaagaac aaccggcucc uggaaaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cuaucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga agaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcacaac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccucu     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagacag acgugagcuc cagcgugauc acaucccugg gggccaucgu cagcugcuac     1320

ggcaagacua aguguacugc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacguuaaua agcaggaggg caagagccuc uacgugaaag gggagcccau cauuaacuuc     1500

uacgacccac ugguuuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgugauu     1680

cugcuguccc ucaucgccgu ggggcugcug cuuuacugca aggcccggug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1316
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1316
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      660

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      720

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      780

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      900

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      960

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc     1020

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc     1080

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc     1140

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1200

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1260

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1320

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1500

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1620

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1680

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1800

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1860

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1317
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1317
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      600

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      660

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      720

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      780

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      840

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      900

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      960

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug     1080

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug     1140

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1200

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1260

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1320

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1440

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1500

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1620

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1680

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1740

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1800

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1860

aucgccgucg ggcugcuccu guacugcaag gcgcgcugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1318
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1318
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      600

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      660

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      720

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      780

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      840

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      900

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      960

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc     1080

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc     1140

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1200

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1260

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1320

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1440

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1500

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1560

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1620

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1680

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1740

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1800

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1860

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1319
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1319
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      600

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      660

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      720

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      780

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      840

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      900

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      960

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc     1020

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua     1080

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug     1140

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1200

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1260

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1320

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1380

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1440

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1500

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1560

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1620

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1680

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1740

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1800

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1860

aucgcuguag gccuucuguu guacugcaag gccaggugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1320
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1320
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      600

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      660

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      720

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      780

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      840

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      900

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      960

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc     1020

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug     1080

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug     1140

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1200

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1260

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1320

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1380

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1440

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1500

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1620

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1680

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1800

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1860

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1321
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1321
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      600

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      660

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      720

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      780

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      840

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      900

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      960

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc     1020

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug     1080

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc     1140

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1200

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1260

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1320

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1380

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1440

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1500

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1560

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1620

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1680

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1740

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1800

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1860

aucgcggucg ggcugcuccu guacugcaag gcccggugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1322
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1322
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuauuaa uauuaaaagc aaaugcuauu accacaauac uuacugcugu aaccuucugc      300

uuugccucug gccaaaacau aacagaagaa uuuuaucaau caacuugcuc cgcuguaagc      360

aaaggcuacc uaucagcauu acgcaccggc ugguacacau caguaauaac aauagaacua      420

uccaacauaa aagaaaauaa augcaacgga acagacgcaa aaguaaaauu aauaaaacaa      480

gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aaguacucca      540

gccaccaaca acagagcaag aagagaauua ccacgauuua ugaacuacac acuaaacaau      600

gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac gcagauucuu aggcuuccuc      660

cuagguguag gcucagcaau cgccucagga guggcaguuu guaaaguacu acaccuagaa      720

ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa acaaagcagu aguaucguua      780

uccaauggag ucucaguauu gacauucaaa guauuagacc uaaaaaauua uauagauaaa      840

caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa guaacauaga aaccguaaua      900

gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc gagaauuuuc aguaaacgca      960

gguguaacaa caccaguaag cacauacaug cuaacaaaua gugaacuauu aucucuaauu     1020

aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga guaacaacgu acaaauagua     1080

agacaacaau ccuauagcau aaugugcauu auaaaagaag aaguacuagc auauguaguc     1140

caacuaccac uauacggcgu aauagacaca ccaugcugga aacuacacac cucaccccua     1200

ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa ccaggacaga cagaggcugg     1260

uacugcgaua acgcaggauc uguuucauuc uucccccaag cagaaacaug caaaguacaa     1320

ucaaacagag uauuuuguga uaccaugaac ucacucacau uaccauccga agucaaccuc     1380

ugcaacguag acauauucaa ccccaaauac gacugcaaaa uaaugaccuc aaaaacagau     1440

guaucaucau caguaaucac aucacuagga gcuaucguau cuuguuaugg aaaaacaaaa     1500

ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau ucucaaaugg augugacuau     1560

guaucaaaca aaggaguaga caccguaagc guaggcaaua cacuauauua cguaaauaaa     1620

caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa uaaacuucua ugacccccua     1680

guauucccau cagaugaauu ugacgcaagc auaucacaag ucaacgaaaa aauaaaccaa     1740

ucacuggcau ucauucgcaa aucagaugaa cuucuccaca acguaaacgc ugguaaaagc     1800

acuacaaaca uaaugauaac aacaaucauc auugucauaa uaguuauucu auuaucacua     1860

aucgcaguag gauuacuacu auacuguaaa gcgagguaag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1323
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1323
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accacaaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgaaccggc ugguacaccu ccgugaucac caucgagcug      420

ucaaacauca aggagaacaa gugcaacggg accgaugcca agguuaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccacuccg      540

gcaaccaaca accgcgccag gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      600

gccaagaaga cgaaugugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      660

cuaggggugg gcuccgccau cgcgagcggc gucgccgugu gcaagguguu gcaccucgag      720

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu gguaagccuc      780

uccaacggcg ucagcguucu gaccuucaag gugcuggacc ucaagaacua uaucgacaag      840

cagcugcugc ccauccugaa caagcagagc ugcuccaucu caaacaucga aacggugauu      900

gaguuccagc agaagaacaa ccggcuccug gaaaucaccc gcgaguucag cgugaacgcc      960

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu aucccugauc     1020

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc     1080

cggcagcagu ccuacagcau caugugcauc aucaaggaag aggugcuggc guacgugguc     1140

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1200

ugcacaacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1260

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1320

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccucuga gguaaaccuc     1380

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagacagac     1440

gugagcucca gcgugaucac aucccugggg gccaucguca gcugcuacgg caagacuaag     1500

uguacugcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1560

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cguuaauaag     1620

caggagggca agagccucua cgugaaaggg gagcccauca uuaacuucua cgacccacug     1680

guuuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1740

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1800

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauucu gcugucccuc     1860

aucgccgugg ggcugcugcu uuacugcaag gcccggugag gacuaguguc caccuguccc     1920

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1324
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1324
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1325
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1325
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      600

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      720

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      780

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug      960

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1020

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1440

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1560

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1680

aucgccgucg ggcugcuccu guacugcaag gcgcgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1326
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1326
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1327
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1327
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      600

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      720

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      780

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua      900

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug      960

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1020

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1080

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1140

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1200

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1260

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1320

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1380

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1440

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1500

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1560

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1620

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1680

aucgcuguag gccuucuguu guacugcaag gccaggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1328
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1328
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1329
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1329
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      600

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      720

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      780

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug      900

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc      960

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1020

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1080

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1140

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1200

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1260

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1320

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1380

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1440

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1500

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1560

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1680

aucgcggucg ggcugcuccu guacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1330
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1330
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuauuaa uauuaaaagc aaaugcuauu accacaauac uuacugcugu aaccuucugc      120

uuugccucug gccaaaacau aacagaagaa uuuuaucaau caacuugcuc cgcuguaagc      180

aaaggcuacc uaucagcauu acgcaccggc ugguacacau caguaauaac aauagaacua      240

uccaacauaa aagaaaauaa augcaacgga acagacgcaa aaguaaaauu aauaaaacaa      300

gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aaguacucca      360

gccaccaaca acagagcaag aagagaauua ccacgauuua ugaacuacac acuaaacaau      420

gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac gcagauucuu aggcuuccuc      480

cuagguguag gcucagcaau cgccucagga guggcaguuu guaaaguacu acaccuagaa      540

ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa acaaagcagu aguaucguua      600

uccaauggag ucucaguauu gacauucaaa guauuagacc uaaaaaauua uauagauaaa      660

caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa guaacauaga aaccguaaua      720

gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc gagaauuuuc aguaaacgca      780

gguguaacaa caccaguaag cacauacaug cuaacaaaua gugaacuauu aucucuaauu      840

aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga guaacaacgu acaaauagua      900

agacaacaau ccuauagcau aaugugcauu auaaaagaag aaguacuagc auauguaguc      960

caacuaccac uauacggcgu aauagacaca ccaugcugga aacuacacac cucaccccua     1020

ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa ccaggacaga cagaggcugg     1080

uacugcgaua acgcaggauc uguuucauuc uucccccaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuuguga uaccaugaac ucacucacau uaccauccga agucaaccuc     1200

ugcaacguag acauauucaa ccccaaauac gacugcaaaa uaaugaccuc aaaaacagau     1260

guaucaucau caguaaucac aucacuagga gcuaucguau cuuguuaugg aaaaacaaaa     1320

ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau ucucaaaugg augugacuau     1380

guaucaaaca aaggaguaga caccguaagc guaggcaaua cacuauauua cguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa uaaacuucua ugacccccua     1500

guauucccau cagaugaauu ugacgcaagc auaucacaag ucaacgaaaa aauaaaccaa     1560

ucacuggcau ucauucgcaa aucagaugaa cuucuccaca acguaaacgc ugguaaaagc     1620

acuacaaaca uaaugauaac aacaaucauc auugucauaa uaguuauucu auuaucacua     1680

aucgcaguag gauuacuacu auacuguaaa gcgagguaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1331
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1331
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accacaaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgaaccggc ugguacaccu ccgugaucac caucgagcug      240

ucaaacauca aggagaacaa gugcaacggg accgaugcca agguuaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccacuccg      360

gcaaccaaca accgcgccag gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaaugugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cuaggggugg gcuccgccau cgcgagcggc gucgccgugu gcaagguguu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu gguaagccuc      600

uccaacggcg ucagcguucu gaccuucaag gugcuggacc ucaagaacua uaucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucu caaacaucga aacggugauu      720

gaguuccagc agaagaacaa ccggcuccug gaaaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu aucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggaag aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcacaacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccucuga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagacagac     1260

gugagcucca gcgugaucac aucccugggg gccaucguca gcugcuacgg caagacuaag     1320

uguacugcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cguuaauaag     1440

caggagggca agagccucua cgugaaaggg gagcccauca uuaacuucua cgacccacug     1500

guuuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauucu gcugucccuc     1680

aucgccgugg ggcugcugcu uuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  1332
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1332
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1333
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1333
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1334
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1334
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1335
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1335
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1336
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1336
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1337
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1337
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1338
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1338
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaaugcuauu accacaauac      120

uuacugcugu aaccuucugc uuugccucug gccaaaacau aacagaagaa uuuuaucaau      180

caacuugcuc cgcuguaagc aaaggcuacc uaucagcauu acgcaccggc ugguacacau      240

caguaauaac aauagaacua uccaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguaaaauu aauaaaacaa gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aaguacucca gccaccaaca acagagcaag aagagaauua ccacgauuua      420

ugaacuacac acuaaacaau gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac      480

gcagauucuu aggcuuccuc cuagguguag gcucagcaau cgccucagga guggcaguuu      540

guaaaguacu acaccuagaa ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa      600

acaaagcagu aguaucguua uccaauggag ucucaguauu gacauucaaa guauuagacc      660

uaaaaaauua uauagauaaa caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa      720

guaacauaga aaccguaaua gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc      780

gagaauuuuc aguaaacgca gguguaacaa caccaguaag cacauacaug cuaacaaaua      840

gugaacuauu aucucuaauu aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga      900

guaacaacgu acaaauagua agacaacaau ccuauagcau aaugugcauu auaaaagaag      960

aaguacuagc auauguaguc caacuaccac uauacggcgu aauagacaca ccaugcugga     1020

aacuacacac cucaccccua ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa     1080

ccaggacaga cagaggcugg uacugcgaua acgcaggauc uguuucauuc uucccccaag     1140

cagaaacaug caaaguacaa ucaaacagag uauuuuguga uaccaugaac ucacucacau     1200

uaccauccga agucaaccuc ugcaacguag acauauucaa ccccaaauac gacugcaaaa     1260

uaaugaccuc aaaaacagau guaucaucau caguaaucac aucacuagga gcuaucguau     1320

cuuguuaugg aaaaacaaaa ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau     1380

ucucaaaugg augugacuau guaucaaaca aaggaguaga caccguaagc guaggcaaua     1440

cacuauauua cguaaauaaa caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa     1500

uaaacuucua ugacccccua guauucccau cagaugaauu ugacgcaagc auaucacaag     1560

ucaacgaaaa aauaaaccaa ucacuggcau ucauucgcaa aucagaugaa cuucuccaca     1620

acguaaacgc ugguaaaagc acuacaaaca uaaugauaac aacaaucauc auugucauaa     1680

uaguuauucu auuaucacua aucgcaguag gauuacuacu auacuguaaa gcgagguaag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1339
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1339
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accacaaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgaaccggc ugguacaccu      240

ccgugaucac caucgagcug ucaaacauca aggagaacaa gugcaacggg accgaugcca      300

agguuaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccacuccg gcaaccaaca accgcgccag gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaaugugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cuaggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaagguguu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu gguaagccuc uccaacggcg ucagcguucu gaccuucaag gugcuggacc      660

ucaagaacua uaucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccaucu      720

caaacaucga aacggugauu gaguuccagc agaagaacaa ccggcuccug gaaaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu aucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggaag      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcacaacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccucuga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagacagac gugagcucca gcgugaucac aucccugggg gccaucguca     1320

gcugcuacgg caagacuaag uguacugcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cguuaauaag caggagggca agagccucua cgugaaaggg gagcccauca     1500

uuaacuucua cgacccacug guuuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauucu gcugucccuc aucgccgugg ggcugcugcu uuacugcaag gcccggugag     1740

gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu gccaaauaaa     1800

caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1340
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1340
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1341
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1341
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1342
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1342
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1343
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1343
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1344
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1344
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1345
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1345
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1346
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1346
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaaugcuauu accacaauac      120

uuacugcugu aaccuucugc uuugccucug gccaaaacau aacagaagaa uuuuaucaau      180

caacuugcuc cgcuguaagc aaaggcuacc uaucagcauu acgcaccggc ugguacacau      240

caguaauaac aauagaacua uccaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguaaaauu aauaaaacaa gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aaguacucca gccaccaaca acagagcaag aagagaauua ccacgauuua      420

ugaacuacac acuaaacaau gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac      480

gcagauucuu aggcuuccuc cuagguguag gcucagcaau cgccucagga guggcaguuu      540

guaaaguacu acaccuagaa ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa      600

acaaagcagu aguaucguua uccaauggag ucucaguauu gacauucaaa guauuagacc      660

uaaaaaauua uauagauaaa caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa      720

guaacauaga aaccguaaua gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc      780

gagaauuuuc aguaaacgca gguguaacaa caccaguaag cacauacaug cuaacaaaua      840

gugaacuauu aucucuaauu aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga      900

guaacaacgu acaaauagua agacaacaau ccuauagcau aaugugcauu auaaaagaag      960

aaguacuagc auauguaguc caacuaccac uauacggcgu aauagacaca ccaugcugga     1020

aacuacacac cucaccccua ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa     1080

ccaggacaga cagaggcugg uacugcgaua acgcaggauc uguuucauuc uucccccaag     1140

cagaaacaug caaaguacaa ucaaacagag uauuuuguga uaccaugaac ucacucacau     1200

uaccauccga agucaaccuc ugcaacguag acauauucaa ccccaaauac gacugcaaaa     1260

uaaugaccuc aaaaacagau guaucaucau caguaaucac aucacuagga gcuaucguau     1320

cuuguuaugg aaaaacaaaa ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau     1380

ucucaaaugg augugacuau guaucaaaca aaggaguaga caccguaagc guaggcaaua     1440

cacuauauua cguaaauaaa caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa     1500

uaaacuucua ugacccccua guauucccau cagaugaauu ugacgcaagc auaucacaag     1560

ucaacgaaaa aauaaaccaa ucacuggcau ucauucgcaa aucagaugaa cuucuccaca     1620

acguaaacgc ugguaaaagc acuacaaaca uaaugauaac aacaaucauc auugucauaa     1680

uaguuauucu auuaucacua aucgcaguag gauuacuacu auacuguaaa gcgagguaag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1347
<211>  2002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1347
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accacaaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgaaccggc ugguacaccu      240

ccgugaucac caucgagcug ucaaacauca aggagaacaa gugcaacggg accgaugcca      300

agguuaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccacuccg gcaaccaaca accgcgccag gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaaugugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cuaggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaagguguu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu gguaagccuc uccaacggcg ucagcguucu gaccuucaag gugcuggacc      660

ucaagaacua uaucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccaucu      720

caaacaucga aacggugauu gaguuccagc agaagaacaa ccggcuccug gaaaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu aucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggaag      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcacaacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccucuga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagacagac gugagcucca gcgugaucac aucccugggg gccaucguca     1320

gcugcuacgg caagacuaag uguacugcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cguuaauaag caggagggca agagccucua cgugaaaggg gagcccauca     1500

uuaacuucua cgacccacug guuuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauucu gcugucccuc aucgccgugg ggcugcugcu uuacugcaag gcccggugag     1740

gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag auccuucugu     1800

aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau aaaucuggua     1860

gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1980

ucuuuucaga gccaccagaa uu                                              2002


<210>  1348
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1348
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1349
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1349
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1350
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1350
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1351
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1351
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1352
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1352
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1353
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1353
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc ggugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1354
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1354
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaau gcuauuacca caauacuuac ugcuguaacc      180

uucugcuuug ccucuggcca aaacauaaca gaagaauuuu aucaaucaac uugcuccgcu      240

guaagcaaag gcuaccuauc agcauuacgc accggcuggu acacaucagu aauaacaaua      300

gaacuaucca acauaaaaga aaauaaaugc aacggaacag acgcaaaagu aaaauuaaua      360

aaacaagaac ucgacaaaua caaaaacgca guaacagaau uacaacuacu aaugcaaagu      420

acuccagcca ccaacaacag agcaagaaga gaauuaccac gauuuaugaa cuacacacua      480

aacaaugcaa aaaaaacaaa cguaacacua ucaaaaaaac guaaacgcag auucuuaggc      540

uuccuccuag guguaggcuc agcaaucgcc ucaggagugg caguuuguaa aguacuacac      600

cuagaaggag aaguaaacaa aaucaaaucu gcccuuuuau cgacaaacaa agcaguagua      660

ucguuaucca auggagucuc aguauugaca uucaaaguau uagaccuaaa aaauuauaua      720

gauaaacaac ucuuaccuau cuuaaauaaa caaagcugcu caauaaguaa cauagaaacc      780

guaauagaau uucaacaaaa aaacaauaga cuccuugaga ucacucgaga auuuucagua      840

aacgcaggug uaacaacacc aguaagcaca uacaugcuaa caaauaguga acuauuaucu      900

cuaauuaacg auaugcccau aaccaacgau caaaaaaaac ucaugaguaa caacguacaa      960

auaguaagac aacaauccua uagcauaaug ugcauuauaa aagaagaagu acuagcauau     1020

guaguccaac uaccacuaua cggcguaaua gacacaccau gcuggaaacu acacaccuca     1080

ccccuaugca caacaaauac aaaagaagga ucaaacauau gcuuaaccag gacagacaga     1140

ggcugguacu gcgauaacgc aggaucuguu ucauucuucc cccaagcaga aacaugcaaa     1200

guacaaucaa acagaguauu uugugauacc augaacucac ucacauuacc auccgaaguc     1260

aaccucugca acguagacau auucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1320

acagauguau caucaucagu aaucacauca cuaggagcua ucguaucuug uuauggaaaa     1380

acaaaaugca cagcauccaa caaaaacaga ggaauuauca aaacauucuc aaauggaugu     1440

gacuauguau caaacaaagg aguagacacc guaagcguag gcaauacacu auauuacgua     1500

aauaaacaag aaggaaaauc acuauacgua aaaggugaac caauaauaaa cuucuaugac     1560

ccccuaguau ucccaucaga ugaauuugac gcaagcauau cacaagucaa cgaaaaaaua     1620

aaccaaucac uggcauucau ucgcaaauca gaugaacuuc uccacaacgu aaacgcuggu     1680

aaaagcacua caaacauaau gauaacaaca aucaucauug ucauaauagu uauucuauua     1740

ucacuaaucg caguaggauu acuacuauac uguaaagcga gguaaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1355
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1355
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca caauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcga accggcuggu acaccuccgu gaucaccauc      300

gagcugucaa acaucaagga gaacaagugc aacgggaccg augccaaggu uaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acuccggcaa ccaacaaccg cgccaggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa ugugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccuag gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa gguguugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggua      660

agccucucca acggcgucag cguucugacc uucaaggugc uggaccucaa gaacuauauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucucaaa caucgaaacg      780

gugauugagu uccagcagaa gaacaaccgg cuccuggaaa ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccuaucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaagaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca caaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cucugaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

acagacguga gcuccagcgu gaucacaucc cugggggcca ucgucagcug cuacggcaag     1380

acuaagugua cugccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacguu     1500

aauaagcagg agggcaagag ccucuacgug aaaggggagc ccaucauuaa cuucuacgac     1560

ccacugguuu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauucugcug     1740

ucccucaucg ccguggggcu gcugcuuuac ugcaaggccc ggugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  1356
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1356
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1357
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1357
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1358
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1358
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1359
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1359
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1360
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1360
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1361
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1361
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1362
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1362
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aaugcuauua ccacaauacu uacugcugua accuucugcu uugccucugg ccaaaacaua      180

acagaagaau uuuaucaauc aacuugcucc gcuguaagca aaggcuaccu aucagcauua      240

cgcaccggcu gguacacauc aguaauaaca auagaacuau ccaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguaaaauua auaaaacaag aacucgacaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa aguacuccag ccaccaacaa cagagcaaga      420

agagaauuac cacgauuuau gaacuacaca cuaaacaaug caaaaaaaac aaacguaaca      480

cuaucaaaaa aacguaaacg cagauucuua ggcuuccucc uagguguagg cucagcaauc      540

gccucaggag uggcaguuug uaaaguacua caccuagaag gagaaguaaa caaaaucaaa      600

ucugcccuuu uaucgacaaa caaagcagua guaucguuau ccaauggagu cucaguauug      660

acauucaaag uauuagaccu aaaaaauuau auagauaaac aacucuuacc uaucuuaaau      720

aaacaaagcu gcucaauaag uaacauagaa accguaauag aauuucaaca aaaaaacaau      780

agacuccuug agaucacucg agaauuuuca guaaacgcag guguaacaac accaguaagc      840

acauacaugc uaacaaauag ugaacuauua ucucuaauua acgauaugcc cauaaccaac      900

gaucaaaaaa aacucaugag uaacaacgua caaauaguaa gacaacaauc cuauagcaua      960

augugcauua uaaaagaaga aguacuagca uauguagucc aacuaccacu auacggcgua     1020

auagacacac caugcuggaa acuacacacc ucaccccuau gcacaacaaa uacaaaagaa     1080

ggaucaaaca uaugcuuaac caggacagac agaggcuggu acugcgauaa cgcaggaucu     1140

guuucauucu ucccccaagc agaaacaugc aaaguacaau caaacagagu auuuugugau     1200

accaugaacu cacucacauu accauccgaa gucaaccucu gcaacguaga cauauucaac     1260

cccaaauacg acugcaaaau aaugaccuca aaaacagaug uaucaucauc aguaaucaca     1320

ucacuaggag cuaucguauc uuguuaugga aaaacaaaau gcacagcauc caacaaaaac     1380

agaggaauua ucaaaacauu cucaaaugga ugugacuaug uaucaaacaa aggaguagac     1440

accguaagcg uaggcaauac acuauauuac guaaauaaac aagaaggaaa aucacuauac     1500

guaaaaggug aaccaauaau aaacuucuau gacccccuag uauucccauc agaugaauuu     1560

gacgcaagca uaucacaagu caacgaaaaa auaaaccaau cacuggcauu cauucgcaaa     1620

ucagaugaac uucuccacaa cguaaacgcu gguaaaagca cuacaaacau aaugauaaca     1680

acaaucauca uugucauaau aguuauucua uuaucacuaa ucgcaguagg auuacuacua     1740

uacuguaaag cgagguaagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1363
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1363
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccacaauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgaaccggcu gguacaccuc cgugaucacc aucgagcugu caaacaucaa ggagaacaag      300

ugcaacggga ccgaugccaa gguuaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacuccgg caaccaacaa ccgcgccagg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaaugugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uagggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caagguguug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug guaagccucu ccaacggcgu cagcguucug      660

accuucaagg ugcuggaccu caagaacuau aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucuc aaacaucgaa acggugauug aguuccagca gaagaacaac      780

cggcuccugg aaaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccua ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggaaga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcacaaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccucugag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagacagacg ugagcuccag cgugaucaca     1320

ucccuggggg ccaucgucag cugcuacggc aagacuaagu guacugccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac guuaauaagc aggagggcaa gagccucuac     1500

gugaaagggg agcccaucau uaacuucuac gacccacugg uuuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauucug cugucccuca ucgccguggg gcugcugcuu     1740

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1800

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1364
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1364
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1365
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1365
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1366
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1366
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1367
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1367
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1368
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1368
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1369
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1369
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc ggugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1370
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1370
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaau gcuauuacca caauacuuac ugcuguaacc      180

uucugcuuug ccucuggcca aaacauaaca gaagaauuuu aucaaucaac uugcuccgcu      240

guaagcaaag gcuaccuauc agcauuacgc accggcuggu acacaucagu aauaacaaua      300

gaacuaucca acauaaaaga aaauaaaugc aacggaacag acgcaaaagu aaaauuaaua      360

aaacaagaac ucgacaaaua caaaaacgca guaacagaau uacaacuacu aaugcaaagu      420

acuccagcca ccaacaacag agcaagaaga gaauuaccac gauuuaugaa cuacacacua      480

aacaaugcaa aaaaaacaaa cguaacacua ucaaaaaaac guaaacgcag auucuuaggc      540

uuccuccuag guguaggcuc agcaaucgcc ucaggagugg caguuuguaa aguacuacac      600

cuagaaggag aaguaaacaa aaucaaaucu gcccuuuuau cgacaaacaa agcaguagua      660

ucguuaucca auggagucuc aguauugaca uucaaaguau uagaccuaaa aaauuauaua      720

gauaaacaac ucuuaccuau cuuaaauaaa caaagcugcu caauaaguaa cauagaaacc      780

guaauagaau uucaacaaaa aaacaauaga cuccuugaga ucacucgaga auuuucagua      840

aacgcaggug uaacaacacc aguaagcaca uacaugcuaa caaauaguga acuauuaucu      900

cuaauuaacg auaugcccau aaccaacgau caaaaaaaac ucaugaguaa caacguacaa      960

auaguaagac aacaauccua uagcauaaug ugcauuauaa aagaagaagu acuagcauau     1020

guaguccaac uaccacuaua cggcguaaua gacacaccau gcuggaaacu acacaccuca     1080

ccccuaugca caacaaauac aaaagaagga ucaaacauau gcuuaaccag gacagacaga     1140

ggcugguacu gcgauaacgc aggaucuguu ucauucuucc cccaagcaga aacaugcaaa     1200

guacaaucaa acagaguauu uugugauacc augaacucac ucacauuacc auccgaaguc     1260

aaccucugca acguagacau auucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1320

acagauguau caucaucagu aaucacauca cuaggagcua ucguaucuug uuauggaaaa     1380

acaaaaugca cagcauccaa caaaaacaga ggaauuauca aaacauucuc aaauggaugu     1440

gacuauguau caaacaaagg aguagacacc guaagcguag gcaauacacu auauuacgua     1500

aauaaacaag aaggaaaauc acuauacgua aaaggugaac caauaauaaa cuucuaugac     1560

ccccuaguau ucccaucaga ugaauuugac gcaagcauau cacaagucaa cgaaaaaaua     1620

aaccaaucac uggcauucau ucgcaaauca gaugaacuuc uccacaacgu aaacgcuggu     1680

aaaagcacua caaacauaau gauaacaaca aucaucauug ucauaauagu uauucuauua     1740

ucacuaaucg caguaggauu acuacuauac uguaaagcga gguaaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1371
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1371
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca caauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcga accggcuggu acaccuccgu gaucaccauc      300

gagcugucaa acaucaagga gaacaagugc aacgggaccg augccaaggu uaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acuccggcaa ccaacaaccg cgccaggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa ugugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccuag gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa gguguugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggua      660

agccucucca acggcgucag cguucugacc uucaaggugc uggaccucaa gaacuauauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucucaaa caucgaaacg      780

gugauugagu uccagcagaa gaacaaccgg cuccuggaaa ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccuaucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaagaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca caaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cucugaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

acagacguga gcuccagcgu gaucacaucc cugggggcca ucgucagcug cuacggcaag     1380

acuaagugua cugccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacguu     1500

aauaagcagg agggcaagag ccucuacgug aaaggggagc ccaucauuaa cuucuacgac     1560

ccacugguuu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauucugcug     1740

ucccucaucg ccguggggcu gcugcuuuac ugcaaggccc ggugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  1372
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1372
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1373
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1373
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1374
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1374
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1375
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1375
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1376
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1376
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1377
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1377
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1378
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1378
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aaugcuauua ccacaauacu uacugcugua accuucugcu uugccucugg ccaaaacaua      180

acagaagaau uuuaucaauc aacuugcucc gcuguaagca aaggcuaccu aucagcauua      240

cgcaccggcu gguacacauc aguaauaaca auagaacuau ccaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguaaaauua auaaaacaag aacucgacaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa aguacuccag ccaccaacaa cagagcaaga      420

agagaauuac cacgauuuau gaacuacaca cuaaacaaug caaaaaaaac aaacguaaca      480

cuaucaaaaa aacguaaacg cagauucuua ggcuuccucc uagguguagg cucagcaauc      540

gccucaggag uggcaguuug uaaaguacua caccuagaag gagaaguaaa caaaaucaaa      600

ucugcccuuu uaucgacaaa caaagcagua guaucguuau ccaauggagu cucaguauug      660

acauucaaag uauuagaccu aaaaaauuau auagauaaac aacucuuacc uaucuuaaau      720

aaacaaagcu gcucaauaag uaacauagaa accguaauag aauuucaaca aaaaaacaau      780

agacuccuug agaucacucg agaauuuuca guaaacgcag guguaacaac accaguaagc      840

acauacaugc uaacaaauag ugaacuauua ucucuaauua acgauaugcc cauaaccaac      900

gaucaaaaaa aacucaugag uaacaacgua caaauaguaa gacaacaauc cuauagcaua      960

augugcauua uaaaagaaga aguacuagca uauguagucc aacuaccacu auacggcgua     1020

auagacacac caugcuggaa acuacacacc ucaccccuau gcacaacaaa uacaaaagaa     1080

ggaucaaaca uaugcuuaac caggacagac agaggcuggu acugcgauaa cgcaggaucu     1140

guuucauucu ucccccaagc agaaacaugc aaaguacaau caaacagagu auuuugugau     1200

accaugaacu cacucacauu accauccgaa gucaaccucu gcaacguaga cauauucaac     1260

cccaaauacg acugcaaaau aaugaccuca aaaacagaug uaucaucauc aguaaucaca     1320

ucacuaggag cuaucguauc uuguuaugga aaaacaaaau gcacagcauc caacaaaaac     1380

agaggaauua ucaaaacauu cucaaaugga ugugacuaug uaucaaacaa aggaguagac     1440

accguaagcg uaggcaauac acuauauuac guaaauaaac aagaaggaaa aucacuauac     1500

guaaaaggug aaccaauaau aaacuucuau gacccccuag uauucccauc agaugaauuu     1560

gacgcaagca uaucacaagu caacgaaaaa auaaaccaau cacuggcauu cauucgcaaa     1620

ucagaugaac uucuccacaa cguaaacgcu gguaaaagca cuacaaacau aaugauaaca     1680

acaaucauca uugucauaau aguuauucua uuaucacuaa ucgcaguagg auuacuacua     1740

uacuguaaag cgagguaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1379
<211>  2037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1379
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccacaauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgaaccggcu gguacaccuc cgugaucacc aucgagcugu caaacaucaa ggagaacaag      300

ugcaacggga ccgaugccaa gguuaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacuccgg caaccaacaa ccgcgccagg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaaugugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uagggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caagguguug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug guaagccucu ccaacggcgu cagcguucug      660

accuucaagg ugcuggaccu caagaacuau aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucuc aaacaucgaa acggugauug aguuccagca gaagaacaac      780

cggcuccugg aaaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccua ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggaaga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcacaaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccucugag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagacagacg ugagcuccag cgugaucaca     1320

ucccuggggg ccaucgucag cugcuacggc aagacuaagu guacugccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac guuaauaagc aggagggcaa gagccucuac     1500

gugaaagggg agcccaucau uaacuucuac gacccacugg uuuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauucug cugucccuca ucgccguggg gcugcugcuu     1740

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1800

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1860

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1980

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2037


<210>  1380
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1380
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1381
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1381
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1382
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1382
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1383
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1383
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1384
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1384
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1385
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1385
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1386
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1386
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aaugcuauua ccacaauacu uacugcugua accuucugcu uugccucugg ccaaaacaua      180

acagaagaau uuuaucaauc aacuugcucc gcuguaagca aaggcuaccu aucagcauua      240

cgcaccggcu gguacacauc aguaauaaca auagaacuau ccaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguaaaauua auaaaacaag aacucgacaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa aguacuccag ccaccaacaa cagagcaaga      420

agagaauuac cacgauuuau gaacuacaca cuaaacaaug caaaaaaaac aaacguaaca      480

cuaucaaaaa aacguaaacg cagauucuua ggcuuccucc uagguguagg cucagcaauc      540

gccucaggag uggcaguuug uaaaguacua caccuagaag gagaaguaaa caaaaucaaa      600

ucugcccuuu uaucgacaaa caaagcagua guaucguuau ccaauggagu cucaguauug      660

acauucaaag uauuagaccu aaaaaauuau auagauaaac aacucuuacc uaucuuaaau      720

aaacaaagcu gcucaauaag uaacauagaa accguaauag aauuucaaca aaaaaacaau      780

agacuccuug agaucacucg agaauuuuca guaaacgcag guguaacaac accaguaagc      840

acauacaugc uaacaaauag ugaacuauua ucucuaauua acgauaugcc cauaaccaac      900

gaucaaaaaa aacucaugag uaacaacgua caaauaguaa gacaacaauc cuauagcaua      960

augugcauua uaaaagaaga aguacuagca uauguagucc aacuaccacu auacggcgua     1020

auagacacac caugcuggaa acuacacacc ucaccccuau gcacaacaaa uacaaaagaa     1080

ggaucaaaca uaugcuuaac caggacagac agaggcuggu acugcgauaa cgcaggaucu     1140

guuucauucu ucccccaagc agaaacaugc aaaguacaau caaacagagu auuuugugau     1200

accaugaacu cacucacauu accauccgaa gucaaccucu gcaacguaga cauauucaac     1260

cccaaauacg acugcaaaau aaugaccuca aaaacagaug uaucaucauc aguaaucaca     1320

ucacuaggag cuaucguauc uuguuaugga aaaacaaaau gcacagcauc caacaaaaac     1380

agaggaauua ucaaaacauu cucaaaugga ugugacuaug uaucaaacaa aggaguagac     1440

accguaagcg uaggcaauac acuauauuac guaaauaaac aagaaggaaa aucacuauac     1500

guaaaaggug aaccaauaau aaacuucuau gacccccuag uauucccauc agaugaauuu     1560

gacgcaagca uaucacaagu caacgaaaaa auaaaccaau cacuggcauu cauucgcaaa     1620

ucagaugaac uucuccacaa cguaaacgcu gguaaaagca cuacaaacau aaugauaaca     1680

acaaucauca uugucauaau aguuauucua uuaucacuaa ucgcaguagg auuacuacua     1740

uacuguaaag cgagguaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1387
<211>  2033
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1387
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccacaauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgaaccggcu gguacaccuc cgugaucacc aucgagcugu caaacaucaa ggagaacaag      300

ugcaacggga ccgaugccaa gguuaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacuccgg caaccaacaa ccgcgccagg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaaugugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uagggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caagguguug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug guaagccucu ccaacggcgu cagcguucug      660

accuucaagg ugcuggaccu caagaacuau aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucuc aaacaucgaa acggugauug aguuccagca gaagaacaac      780

cggcuccugg aaaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccua ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggaaga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcacaaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccucugag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagacagacg ugagcuccag cgugaucaca     1320

ucccuggggg ccaucgucag cugcuacggc aagacuaagu guacugccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac guuaauaagc aggagggcaa gagccucuac     1500

gugaaagggg agcccaucau uaacuucuac gacccacugg uuuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauucug cugucccuca ucgccguggg gcugcugcuu     1740

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1800

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1860

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1980

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            2033


<210>  1388
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1388
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1389
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1389
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1390
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1390
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1391
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1391
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1392
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1392
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1393
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1393
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1394
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1394
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaaugcu      120

auuaccacaa uacuuacugc uguaaccuuc ugcuuugccu cuggccaaaa cauaacagaa      180

gaauuuuauc aaucaacuug cuccgcugua agcaaaggcu accuaucagc auuacgcacc      240

ggcugguaca caucaguaau aacaauagaa cuauccaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguaaa auuaauaaaa caagaacucg acaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaaguacu ccagccacca acaacagagc aagaagagaa      420

uuaccacgau uuaugaacua cacacuaaac aaugcaaaaa aaacaaacgu aacacuauca      480

aaaaaacgua aacgcagauu cuuaggcuuc cuccuaggug uaggcucagc aaucgccuca      540

ggaguggcag uuuguaaagu acuacaccua gaaggagaag uaaacaaaau caaaucugcc      600

cuuuuaucga caaacaaagc aguaguaucg uuauccaaug gagucucagu auugacauuc      660

aaaguauuag accuaaaaaa uuauauagau aaacaacucu uaccuaucuu aaauaaacaa      720

agcugcucaa uaaguaacau agaaaccgua auagaauuuc aacaaaaaaa caauagacuc      780

cuugagauca cucgagaauu uucaguaaac gcagguguaa caacaccagu aagcacauac      840

augcuaacaa auagugaacu auuaucucua auuaacgaua ugcccauaac caacgaucaa      900

aaaaaacuca ugaguaacaa cguacaaaua guaagacaac aauccuauag cauaaugugc      960

auuauaaaag aagaaguacu agcauaugua guccaacuac cacuauacgg cguaauagac     1020

acaccaugcu ggaaacuaca caccucaccc cuaugcacaa caaauacaaa agaaggauca     1080

aacauaugcu uaaccaggac agacagaggc ugguacugcg auaacgcagg aucuguuuca     1140

uucuuccccc aagcagaaac augcaaagua caaucaaaca gaguauuuug ugauaccaug     1200

aacucacuca cauuaccauc cgaagucaac cucugcaacg uagacauauu caaccccaaa     1260

uacgacugca aaauaaugac cucaaaaaca gauguaucau caucaguaau cacaucacua     1320

ggagcuaucg uaucuuguua uggaaaaaca aaaugcacag cauccaacaa aaacagagga     1380

auuaucaaaa cauucucaaa uggaugugac uauguaucaa acaaaggagu agacaccgua     1440

agcguaggca auacacuaua uuacguaaau aaacaagaag gaaaaucacu auacguaaaa     1500

ggugaaccaa uaauaaacuu cuaugacccc cuaguauucc caucagauga auuugacgca     1560

agcauaucac aagucaacga aaaaauaaac caaucacugg cauucauucg caaaucagau     1620

gaacuucucc acaacguaaa cgcugguaaa agcacuacaa acauaaugau aacaacaauc     1680

aucauuguca uaauaguuau ucuauuauca cuaaucgcag uaggauuacu acuauacugu     1740

aaagcgaggu aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1395
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1395
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacaa uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgaacc      240

ggcugguaca ccuccgugau caccaucgag cugucaaaca ucaaggagaa caagugcaac      300

gggaccgaug ccaagguuaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacu ccggcaacca acaaccgcgc caggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaaugu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuagggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu guugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cgugguaagc cucuccaacg gcgucagcgu ucugaccuuc      660

aaggugcugg accucaagaa cuauaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucucaaacau cgaaacggug auugaguucc agcagaagaa caaccggcuc      780

cuggaaauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccuaucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aagaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacaa ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccuc ugagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagaca gacgugagcu ccagcgugau cacaucccug     1320

ggggccaucg ucagcugcua cggcaagacu aaguguacug ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacguuaau aagcaggagg gcaagagccu cuacgugaaa     1500

ggggagccca ucauuaacuu cuacgaccca cugguuuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ucugcugucc cucaucgccg uggggcugcu gcuuuacugc     1740

aaggcccggu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1800

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  1396
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1396
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1397
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1397
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1398
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1398
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1399
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1399
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccaggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1400
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1400
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1401
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1401
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1402
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1402
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaaugcua uuaccacaau acuuacugcu guaaccuucu gcuuugccuc uggccaaaac      180

auaacagaag aauuuuauca aucaacuugc uccgcuguaa gcaaaggcua ccuaucagca      240

uuacgcaccg gcugguacac aucaguaaua acaauagaac uauccaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguaaaa uuaauaaaac aagaacucga caaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaaguacuc cagccaccaa caacagagca      420

agaagagaau uaccacgauu uaugaacuac acacuaaaca augcaaaaaa aacaaacgua      480

acacuaucaa aaaaacguaa acgcagauuc uuaggcuucc uccuaggugu aggcucagca      540

aucgccucag gaguggcagu uuguaaagua cuacaccuag aaggagaagu aaacaaaauc      600

aaaucugccc uuuuaucgac aaacaaagca guaguaucgu uauccaaugg agucucagua      660

uugacauuca aaguauuaga ccuaaaaaau uauauagaua aacaacucuu accuaucuua      720

aauaaacaaa gcugcucaau aaguaacaua gaaaccguaa uagaauuuca acaaaaaaac      780

aauagacucc uugagaucac ucgagaauuu ucaguaaacg cagguguaac aacaccagua      840

agcacauaca ugcuaacaaa uagugaacua uuaucucuaa uuaacgauau gcccauaacc      900

aacgaucaaa aaaaacucau gaguaacaac guacaaauag uaagacaaca auccuauagc      960

auaaugugca uuauaaaaga agaaguacua gcauauguag uccaacuacc acuauacggc     1020

guaauagaca caccaugcug gaaacuacac accucacccc uaugcacaac aaauacaaaa     1080

gaaggaucaa acauaugcuu aaccaggaca gacagaggcu gguacugcga uaacgcagga     1140

ucuguuucau ucuuccccca agcagaaaca ugcaaaguac aaucaaacag aguauuuugu     1200

gauaccauga acucacucac auuaccaucc gaagucaacc ucugcaacgu agacauauuc     1260

aaccccaaau acgacugcaa aauaaugacc ucaaaaacag auguaucauc aucaguaauc     1320

acaucacuag gagcuaucgu aucuuguuau ggaaaaacaa aaugcacagc auccaacaaa     1380

aacagaggaa uuaucaaaac auucucaaau ggaugugacu auguaucaaa caaaggagua     1440

gacaccguaa gcguaggcaa uacacuauau uacguaaaua aacaagaagg aaaaucacua     1500

uacguaaaag gugaaccaau aauaaacuuc uaugaccccc uaguauuccc aucagaugaa     1560

uuugacgcaa gcauaucaca agucaacgaa aaaauaaacc aaucacuggc auucauucgc     1620

aaaucagaug aacuucucca caacguaaac gcugguaaaa gcacuacaaa cauaaugaua     1680

acaacaauca ucauugucau aauaguuauu cuauuaucac uaaucgcagu aggauuacua     1740

cuauacugua aagcgaggua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1403
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1403
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccacaau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgaaccg gcugguacac cuccgugauc accaucgagc ugucaaacau caaggagaac      300

aagugcaacg ggaccgaugc caagguuaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccacuc cggcaaccaa caaccgcgcc      420

aggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaaugug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccuaggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug uugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc gugguaagcc ucuccaacgg cgucagcguu      660

cugaccuuca aggugcugga ccucaagaac uauaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cucaaacauc gaaacgguga uugaguucca gcagaagaac      780

aaccggcucc uggaaaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cuaucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga agaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcacaac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccucu gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagacag acgugagcuc cagcgugauc     1320

acaucccugg gggccaucgu cagcugcuac ggcaagacua aguguacugc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacguuaaua agcaggaggg caagagccuc     1500

uacgugaaag gggagcccau cauuaacuuc uacgacccac ugguuuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauu cugcuguccc ucaucgccgu ggggcugcug     1740

cuuuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1800

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1404
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1404
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1405
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1405
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1406
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1406
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1407
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1407
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1408
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1408
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1409
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1409
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1410
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1410
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaaugcu      120

auuaccacaa uacuuacugc uguaaccuuc ugcuuugccu cuggccaaaa cauaacagaa      180

gaauuuuauc aaucaacuug cuccgcugua agcaaaggcu accuaucagc auuacgcacc      240

ggcugguaca caucaguaau aacaauagaa cuauccaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguaaa auuaauaaaa caagaacucg acaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaaguacu ccagccacca acaacagagc aagaagagaa      420

uuaccacgau uuaugaacua cacacuaaac aaugcaaaaa aaacaaacgu aacacuauca      480

aaaaaacgua aacgcagauu cuuaggcuuc cuccuaggug uaggcucagc aaucgccuca      540

ggaguggcag uuuguaaagu acuacaccua gaaggagaag uaaacaaaau caaaucugcc      600

cuuuuaucga caaacaaagc aguaguaucg uuauccaaug gagucucagu auugacauuc      660

aaaguauuag accuaaaaaa uuauauagau aaacaacucu uaccuaucuu aaauaaacaa      720

agcugcucaa uaaguaacau agaaaccgua auagaauuuc aacaaaaaaa caauagacuc      780

cuugagauca cucgagaauu uucaguaaac gcagguguaa caacaccagu aagcacauac      840

augcuaacaa auagugaacu auuaucucua auuaacgaua ugcccauaac caacgaucaa      900

aaaaaacuca ugaguaacaa cguacaaaua guaagacaac aauccuauag cauaaugugc      960

auuauaaaag aagaaguacu agcauaugua guccaacuac cacuauacgg cguaauagac     1020

acaccaugcu ggaaacuaca caccucaccc cuaugcacaa caaauacaaa agaaggauca     1080

aacauaugcu uaaccaggac agacagaggc ugguacugcg auaacgcagg aucuguuuca     1140

uucuuccccc aagcagaaac augcaaagua caaucaaaca gaguauuuug ugauaccaug     1200

aacucacuca cauuaccauc cgaagucaac cucugcaacg uagacauauu caaccccaaa     1260

uacgacugca aaauaaugac cucaaaaaca gauguaucau caucaguaau cacaucacua     1320

ggagcuaucg uaucuuguua uggaaaaaca aaaugcacag cauccaacaa aaacagagga     1380

auuaucaaaa cauucucaaa uggaugugac uauguaucaa acaaaggagu agacaccgua     1440

agcguaggca auacacuaua uuacguaaau aaacaagaag gaaaaucacu auacguaaaa     1500

ggugaaccaa uaauaaacuu cuaugacccc cuaguauucc caucagauga auuugacgca     1560

agcauaucac aagucaacga aaaaauaaac caaucacugg cauucauucg caaaucagau     1620

gaacuucucc acaacguaaa cgcugguaaa agcacuacaa acauaaugau aacaacaauc     1680

aucauuguca uaauaguuau ucuauuauca cuaaucgcag uaggauuacu acuauacugu     1740

aaagcgaggu aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1411
<211>  2015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1411
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacaa uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgaacc      240

ggcugguaca ccuccgugau caccaucgag cugucaaaca ucaaggagaa caagugcaac      300

gggaccgaug ccaagguuaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacu ccggcaacca acaaccgcgc caggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaaugu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuagggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu guugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cgugguaagc cucuccaacg gcgucagcgu ucugaccuuc      660

aaggugcugg accucaagaa cuauaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucucaaacau cgaaacggug auugaguucc agcagaagaa caaccggcuc      780

cuggaaauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccuaucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aagaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacaa ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccuc ugagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagaca gacgugagcu ccagcgugau cacaucccug     1320

ggggccaucg ucagcugcua cggcaagacu aaguguacug ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacguuaau aagcaggagg gcaagagccu cuacgugaaa     1500

ggggagccca ucauuaacuu cuacgaccca cugguuuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ucugcugucc cucaucgccg uggggcugcu gcuuuacugc     1740

aaggcccggu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1800

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1860

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1980

cccccccaaa ggcucuuuuc agagccacca gaauu                                2015


<210>  1412
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1412
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1413
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1413
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1414
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1414
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1415
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1415
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1416
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1416
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1417
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1417
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cggugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1418
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1418
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa ugcuauuacc acaauacuua cugcuguaac cuucugcuuu      240

gccucuggcc aaaacauaac agaagaauuu uaucaaucaa cuugcuccgc uguaagcaaa      300

ggcuaccuau cagcauuacg caccggcugg uacacaucag uaauaacaau agaacuaucc      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uaaaauuaau aaaacaagaa      420

cucgacaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaaag uacuccagcc      480

accaacaaca gagcaagaag agaauuacca cgauuuauga acuacacacu aaacaaugca      540

aaaaaaacaa acguaacacu aucaaaaaaa cguaaacgca gauucuuagg cuuccuccua      600

gguguaggcu cagcaaucgc cucaggagug gcaguuugua aaguacuaca ccuagaagga      660

gaaguaaaca aaaucaaauc ugcccuuuua ucgacaaaca aagcaguagu aucguuaucc      720

aauggagucu caguauugac auucaaagua uuagaccuaa aaaauuauau agauaaacaa      780

cucuuaccua ucuuaaauaa acaaagcugc ucaauaagua acauagaaac cguaauagaa      840

uuucaacaaa aaaacaauag acuccuugag aucacucgag aauuuucagu aaacgcaggu      900

guaacaacac caguaagcac auacaugcua acaaauagug aacuauuauc ucuaauuaac      960

gauaugccca uaaccaacga ucaaaaaaaa cucaugagua acaacguaca aauaguaaga     1020

caacaauccu auagcauaau gugcauuaua aaagaagaag uacuagcaua uguaguccaa     1080

cuaccacuau acggcguaau agacacacca ugcuggaaac uacacaccuc accccuaugc     1140

acaacaaaua caaaagaagg aucaaacaua ugcuuaacca ggacagacag aggcugguac     1200

ugcgauaacg caggaucugu uucauucuuc ccccaagcag aaacaugcaa aguacaauca     1260

aacagaguau uuugugauac caugaacuca cucacauuac cauccgaagu caaccucugc     1320

aacguagaca uauucaaccc caaauacgac ugcaaaauaa ugaccucaaa aacagaugua     1380

ucaucaucag uaaucacauc acuaggagcu aucguaucuu guuauggaaa aacaaaaugc     1440

acagcaucca acaaaaacag aggaauuauc aaaacauucu caaauggaug ugacuaugua     1500

ucaaacaaag gaguagacac cguaagcgua ggcaauacac uauauuacgu aaauaaacaa     1560

gaaggaaaau cacuauacgu aaaaggugaa ccaauaauaa acuucuauga cccccuagua     1620

uucccaucag augaauuuga cgcaagcaua ucacaaguca acgaaaaaau aaaccaauca     1680

cuggcauuca uucgcaaauc agaugaacuu cuccacaacg uaaacgcugg uaaaagcacu     1740

acaaacauaa ugauaacaac aaucaucauu gucauaauag uuauucuauu aucacuaauc     1800

gcaguaggau uacuacuaua cuguaaagcg agguaaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1419
<211>  2331
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1419
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc acaauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg aaccggcugg uacaccuccg ugaucaccau cgagcuguca      360

aacaucaagg agaacaagug caacgggacc gaugccaagg uuaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacuccggca      480

accaacaacc gcgccaggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga augugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccua      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca agguguugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu aagccucucc      720

aacggcguca gcguucugac cuucaaggug cuggaccuca agaacuauau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucucaa acaucgaaac ggugauugag      840

uuccagcaga agaacaaccg gcuccuggaa aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuauc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaagagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

acaaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccucugaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gacagacgug     1380

agcuccagcg ugaucacauc ccugggggcc aucgucagcu gcuacggcaa gacuaagugu     1440

acugccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu uaauaagcag     1560

gagggcaaga gccucuacgu gaaaggggag cccaucauua acuucuacga cccacugguu     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauucugcu gucccucauc     1800

gccguggggc ugcugcuuua cugcaaggcc cggugaggac uagugaaggg aacacccaaa     1860

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu     1920

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa     1980

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     2040

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     2100

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     2160

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2280

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2331


<210>  1420
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1420
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1421
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1421
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1422
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1422
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1423
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1423
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1424
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1424
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1425
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1425
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1426
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1426
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaaugcuauu accacaauac      120

uuacugcugu aaccuucugc uuugccucug gccaaaacau aacagaagaa uuuuaucaau      180

caacuugcuc cgcuguaagc aaaggcuacc uaucagcauu acgcaccggc ugguacacau      240

caguaauaac aauagaacua uccaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguaaaauu aauaaaacaa gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aaguacucca gccaccaaca acagagcaag aagagaauua ccacgauuua      420

ugaacuacac acuaaacaau gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac      480

gcagauucuu aggcuuccuc cuagguguag gcucagcaau cgccucagga guggcaguuu      540

guaaaguacu acaccuagaa ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa      600

acaaagcagu aguaucguua uccaauggag ucucaguauu gacauucaaa guauuagacc      660

uaaaaaauua uauagauaaa caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa      720

guaacauaga aaccguaaua gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc      780

gagaauuuuc aguaaacgca gguguaacaa caccaguaag cacauacaug cuaacaaaua      840

gugaacuauu aucucuaauu aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga      900

guaacaacgu acaaauagua agacaacaau ccuauagcau aaugugcauu auaaaagaag      960

aaguacuagc auauguaguc caacuaccac uauacggcgu aauagacaca ccaugcugga     1020

aacuacacac cucaccccua ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa     1080

ccaggacaga cagaggcugg uacugcgaua acgcaggauc uguuucauuc uucccccaag     1140

cagaaacaug caaaguacaa ucaaacagag uauuuuguga uaccaugaac ucacucacau     1200

uaccauccga agucaaccuc ugcaacguag acauauucaa ccccaaauac gacugcaaaa     1260

uaaugaccuc aaaaacagau guaucaucau caguaaucac aucacuagga gcuaucguau     1320

cuuguuaugg aaaaacaaaa ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau     1380

ucucaaaugg augugacuau guaucaaaca aaggaguaga caccguaagc guaggcaaua     1440

cacuauauua cguaaauaaa caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa     1500

uaaacuucua ugacccccua guauucccau cagaugaauu ugacgcaagc auaucacaag     1560

ucaacgaaaa aauaaaccaa ucacuggcau ucauucgcaa aucagaugaa cuucuccaca     1620

acguaaacgc ugguaaaagc acuacaaaca uaaugauaac aacaaucauc auugucauaa     1680

uaguuauucu auuaucacua aucgcaguag gauuacuacu auacuguaaa gcgagguaag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1427
<211>  2014
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1427
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accacaaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgaaccggc ugguacaccu      240

ccgugaucac caucgagcug ucaaacauca aggagaacaa gugcaacggg accgaugcca      300

agguuaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccacuccg gcaaccaaca accgcgccag gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaaugugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cuaggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaagguguu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu gguaagccuc uccaacggcg ucagcguucu gaccuucaag gugcuggacc      660

ucaagaacua uaucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccaucu      720

caaacaucga aacggugauu gaguuccagc agaagaacaa ccggcuccug gaaaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu aucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggaag      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcacaacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccucuga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagacagac gugagcucca gcgugaucac aucccugggg gccaucguca     1320

gcugcuacgg caagacuaag uguacugcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cguuaauaag caggagggca agagccucua cgugaaaggg gagcccauca     1500

uuaacuucua cgacccacug guuuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauucu gcugucccuc aucgccgugg ggcugcugcu uuacugcaag gcccggugag     1740

gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug gucaucuguu     1800

ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa ugcauaauaa     1860

aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1980

ccccccaaag gcucuuuuca gagccaccag aauu                                 2014


<210>  1428
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1428
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1429
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1429
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1430
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1430
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1431
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1431
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1432
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1432
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1433
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1433
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cggugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1434
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1434
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa ugcuauuacc acaauacuua cugcuguaac cuucugcuuu      240

gccucuggcc aaaacauaac agaagaauuu uaucaaucaa cuugcuccgc uguaagcaaa      300

ggcuaccuau cagcauuacg caccggcugg uacacaucag uaauaacaau agaacuaucc      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uaaaauuaau aaaacaagaa      420

cucgacaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaaag uacuccagcc      480

accaacaaca gagcaagaag agaauuacca cgauuuauga acuacacacu aaacaaugca      540

aaaaaaacaa acguaacacu aucaaaaaaa cguaaacgca gauucuuagg cuuccuccua      600

gguguaggcu cagcaaucgc cucaggagug gcaguuugua aaguacuaca ccuagaagga      660

gaaguaaaca aaaucaaauc ugcccuuuua ucgacaaaca aagcaguagu aucguuaucc      720

aauggagucu caguauugac auucaaagua uuagaccuaa aaaauuauau agauaaacaa      780

cucuuaccua ucuuaaauaa acaaagcugc ucaauaagua acauagaaac cguaauagaa      840

uuucaacaaa aaaacaauag acuccuugag aucacucgag aauuuucagu aaacgcaggu      900

guaacaacac caguaagcac auacaugcua acaaauagug aacuauuauc ucuaauuaac      960

gauaugccca uaaccaacga ucaaaaaaaa cucaugagua acaacguaca aauaguaaga     1020

caacaauccu auagcauaau gugcauuaua aaagaagaag uacuagcaua uguaguccaa     1080

cuaccacuau acggcguaau agacacacca ugcuggaaac uacacaccuc accccuaugc     1140

acaacaaaua caaaagaagg aucaaacaua ugcuuaacca ggacagacag aggcugguac     1200

ugcgauaacg caggaucugu uucauucuuc ccccaagcag aaacaugcaa aguacaauca     1260

aacagaguau uuugugauac caugaacuca cucacauuac cauccgaagu caaccucugc     1320

aacguagaca uauucaaccc caaauacgac ugcaaaauaa ugaccucaaa aacagaugua     1380

ucaucaucag uaaucacauc acuaggagcu aucguaucuu guuauggaaa aacaaaaugc     1440

acagcaucca acaaaaacag aggaauuauc aaaacauucu caaauggaug ugacuaugua     1500

ucaaacaaag gaguagacac cguaagcgua ggcaauacac uauauuacgu aaauaaacaa     1560

gaaggaaaau cacuauacgu aaaaggugaa ccaauaauaa acuucuauga cccccuagua     1620

uucccaucag augaauuuga cgcaagcaua ucacaaguca acgaaaaaau aaaccaauca     1680

cuggcauuca uucgcaaauc agaugaacuu cuccacaacg uaaacgcugg uaaaagcacu     1740

acaaacauaa ugauaacaac aaucaucauu gucauaauag uuauucuauu aucacuaauc     1800

gcaguaggau uacuacuaua cuguaaagcg agguaaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1435
<211>  2111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1435
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc acaauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg aaccggcugg uacaccuccg ugaucaccau cgagcuguca      360

aacaucaagg agaacaagug caacgggacc gaugccaagg uuaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacuccggca      480

accaacaacc gcgccaggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga augugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccua      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca agguguugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu aagccucucc      720

aacggcguca gcguucugac cuucaaggug cuggaccuca agaacuauau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucucaa acaucgaaac ggugauugag      840

uuccagcaga agaacaaccg gcuccuggaa aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuauc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaagagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

acaaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccucugaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gacagacgug     1380

agcuccagcg ugaucacauc ccugggggcc aucgucagcu gcuacggcaa gacuaagugu     1440

acugccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu uaauaagcag     1560

gagggcaaga gccucuacgu gaaaggggag cccaucauua acuucuacga cccacugguu     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauucugcu gucccucauc     1800

gccguggggc ugcugcuuua cugcaaggcc cggugaggac uaguggaagc auuuuccugg     1860

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau     1920

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga     1980

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     2100

ccaccagaau u                                                          2111


<210>  1436
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1436
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      540

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      600

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      660

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      780

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      840

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      900

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      960

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc     1020

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1080

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1140

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1200

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1380

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1500

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1560

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1680

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1740

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1437
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1437
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      480

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      540

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      600

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      660

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      720

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      780

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      840

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      960

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug     1020

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1080

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1140

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1200

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1320

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1380

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1500

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1560

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1620

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1680

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1740

aucgccgucg ggcugcuccu guacugcaag gcgcgcugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1438
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1438
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      480

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      540

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      600

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      660

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      720

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      780

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      840

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      960

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc     1020

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1080

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1140

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1200

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1320

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1380

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1440

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1500

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1560

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1620

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1680

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1740

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1439
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1439
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      480

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      540

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      600

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      660

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      720

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      780

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      840

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc      900

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua      960

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug     1020

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1080

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1140

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1200

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1260

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1320

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1380

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1440

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1500

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1560

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1620

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1680

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1740

aucgcuguag gccuucuguu guacugcaag gccaggugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1440
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1440
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      480

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      540

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      600

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      660

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      720

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      780

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      840

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      900

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      960

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug     1020

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1080

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1140

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1200

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1260

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1320

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1380

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1500

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1560

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1680

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1740

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1441
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1441
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      480

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      540

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      600

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      660

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      720

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      780

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      840

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc      900

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug      960

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc     1020

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1080

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1140

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1200

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1260

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1320

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1380

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1440

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1500

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1560

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1620

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1680

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1740

aucgcggucg ggcugcuccu guacugcaag gcccggugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1442
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1442
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuauuaa uauuaaaagc aaaugcuauu accacaauac uuacugcugu aaccuucugc      180

uuugccucug gccaaaacau aacagaagaa uuuuaucaau caacuugcuc cgcuguaagc      240

aaaggcuacc uaucagcauu acgcaccggc ugguacacau caguaauaac aauagaacua      300

uccaacauaa aagaaaauaa augcaacgga acagacgcaa aaguaaaauu aauaaaacaa      360

gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aaguacucca      420

gccaccaaca acagagcaag aagagaauua ccacgauuua ugaacuacac acuaaacaau      480

gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac gcagauucuu aggcuuccuc      540

cuagguguag gcucagcaau cgccucagga guggcaguuu guaaaguacu acaccuagaa      600

ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa acaaagcagu aguaucguua      660

uccaauggag ucucaguauu gacauucaaa guauuagacc uaaaaaauua uauagauaaa      720

caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa guaacauaga aaccguaaua      780

gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc gagaauuuuc aguaaacgca      840

gguguaacaa caccaguaag cacauacaug cuaacaaaua gugaacuauu aucucuaauu      900

aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga guaacaacgu acaaauagua      960

agacaacaau ccuauagcau aaugugcauu auaaaagaag aaguacuagc auauguaguc     1020

caacuaccac uauacggcgu aauagacaca ccaugcugga aacuacacac cucaccccua     1080

ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa ccaggacaga cagaggcugg     1140

uacugcgaua acgcaggauc uguuucauuc uucccccaag cagaaacaug caaaguacaa     1200

ucaaacagag uauuuuguga uaccaugaac ucacucacau uaccauccga agucaaccuc     1260

ugcaacguag acauauucaa ccccaaauac gacugcaaaa uaaugaccuc aaaaacagau     1320

guaucaucau caguaaucac aucacuagga gcuaucguau cuuguuaugg aaaaacaaaa     1380

ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau ucucaaaugg augugacuau     1440

guaucaaaca aaggaguaga caccguaagc guaggcaaua cacuauauua cguaaauaaa     1500

caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa uaaacuucua ugacccccua     1560

guauucccau cagaugaauu ugacgcaagc auaucacaag ucaacgaaaa aauaaaccaa     1620

ucacuggcau ucauucgcaa aucagaugaa cuucuccaca acguaaacgc ugguaaaagc     1680

acuacaaaca uaaugauaac aacaaucauc auugucauaa uaguuauucu auuaucacua     1740

aucgcaguag gauuacuacu auacuguaaa gcgagguaag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1443
<211>  1991
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1443
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accacaaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgaaccggc ugguacaccu ccgugaucac caucgagcug      300

ucaaacauca aggagaacaa gugcaacggg accgaugcca agguuaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccacuccg      420

gcaaccaaca accgcgccag gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      480

gccaagaaga cgaaugugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      540

cuaggggugg gcuccgccau cgcgagcggc gucgccgugu gcaagguguu gcaccucgag      600

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu gguaagccuc      660

uccaacggcg ucagcguucu gaccuucaag gugcuggacc ucaagaacua uaucgacaag      720

cagcugcugc ccauccugaa caagcagagc ugcuccaucu caaacaucga aacggugauu      780

gaguuccagc agaagaacaa ccggcuccug gaaaucaccc gcgaguucag cgugaacgcc      840

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu aucccugauc      900

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      960

cggcagcagu ccuacagcau caugugcauc aucaaggaag aggugcuggc guacgugguc     1020

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1080

ugcacaacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1140

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1200

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccucuga gguaaaccuc     1260

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagacagac     1320

gugagcucca gcgugaucac aucccugggg gccaucguca gcugcuacgg caagacuaag     1380

uguacugcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1440

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cguuaauaag     1500

caggagggca agagccucua cgugaaaggg gagcccauca uuaacuucua cgacccacug     1560

guuuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1620

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1680

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauucu gcugucccuc     1740

aucgccgugg ggcugcugcu uuacugcaag gcccggugag gacuaguguc caccuguccc     1800

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1860

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1980

ccaccagaau u                                                          1991


<210>  1444
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1444
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1445
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1445
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1446
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1446
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1447
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1447
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccaggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1448
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1448
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1449
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1449
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1450
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1450
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaaugcua uuaccacaau acuuacugcu guaaccuucu gcuuugccuc uggccaaaac      180

auaacagaag aauuuuauca aucaacuugc uccgcuguaa gcaaaggcua ccuaucagca      240

uuacgcaccg gcugguacac aucaguaaua acaauagaac uauccaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguaaaa uuaauaaaac aagaacucga caaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaaguacuc cagccaccaa caacagagca      420

agaagagaau uaccacgauu uaugaacuac acacuaaaca augcaaaaaa aacaaacgua      480

acacuaucaa aaaaacguaa acgcagauuc uuaggcuucc uccuaggugu aggcucagca      540

aucgccucag gaguggcagu uuguaaagua cuacaccuag aaggagaagu aaacaaaauc      600

aaaucugccc uuuuaucgac aaacaaagca guaguaucgu uauccaaugg agucucagua      660

uugacauuca aaguauuaga ccuaaaaaau uauauagaua aacaacucuu accuaucuua      720

aauaaacaaa gcugcucaau aaguaacaua gaaaccguaa uagaauuuca acaaaaaaac      780

aauagacucc uugagaucac ucgagaauuu ucaguaaacg cagguguaac aacaccagua      840

agcacauaca ugcuaacaaa uagugaacua uuaucucuaa uuaacgauau gcccauaacc      900

aacgaucaaa aaaaacucau gaguaacaac guacaaauag uaagacaaca auccuauagc      960

auaaugugca uuauaaaaga agaaguacua gcauauguag uccaacuacc acuauacggc     1020

guaauagaca caccaugcug gaaacuacac accucacccc uaugcacaac aaauacaaaa     1080

gaaggaucaa acauaugcuu aaccaggaca gacagaggcu gguacugcga uaacgcagga     1140

ucuguuucau ucuuccccca agcagaaaca ugcaaaguac aaucaaacag aguauuuugu     1200

gauaccauga acucacucac auuaccaucc gaagucaacc ucugcaacgu agacauauuc     1260

aaccccaaau acgacugcaa aauaaugacc ucaaaaacag auguaucauc aucaguaauc     1320

acaucacuag gagcuaucgu aucuuguuau ggaaaaacaa aaugcacagc auccaacaaa     1380

aacagaggaa uuaucaaaac auucucaaau ggaugugacu auguaucaaa caaaggagua     1440

gacaccguaa gcguaggcaa uacacuauau uacguaaaua aacaagaagg aaaaucacua     1500

uacguaaaag gugaaccaau aauaaacuuc uaugaccccc uaguauuccc aucagaugaa     1560

uuugacgcaa gcauaucaca agucaacgaa aaaauaaacc aaucacuggc auucauucgc     1620

aaaucagaug aacuucucca caacguaaac gcugguaaaa gcacuacaaa cauaaugaua     1680

acaacaauca ucauugucau aauaguuauu cuauuaucac uaaucgcagu aggauuacua     1740

cuauacugua aagcgaggua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1451
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1451
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccacaau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgaaccg gcugguacac cuccgugauc accaucgagc ugucaaacau caaggagaac      300

aagugcaacg ggaccgaugc caagguuaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccacuc cggcaaccaa caaccgcgcc      420

aggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaaugug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccuaggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug uugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc gugguaagcc ucuccaacgg cgucagcguu      660

cugaccuuca aggugcugga ccucaagaac uauaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cucaaacauc gaaacgguga uugaguucca gcagaagaac      780

aaccggcucc uggaaaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cuaucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga agaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcacaac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccucu gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagacag acgugagcuc cagcgugauc     1320

acaucccugg gggccaucgu cagcugcuac ggcaagacua aguguacugc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacguuaaua agcaggaggg caagagccuc     1500

uacgugaaag gggagcccau cauuaacuuc uacgacccac ugguuuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauu cugcuguccc ucaucgccgu ggggcugcug     1740

cuuuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1800

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1452
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1452
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1453
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1453
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1454
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1454
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1455
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1455
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccaggug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1456
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1456
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1457
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1457
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccggug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1458
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1458
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaaugcua uuaccacaau acuuacugcu      120

guaaccuucu gcuuugccuc uggccaaaac auaacagaag aauuuuauca aucaacuugc      180

uccgcuguaa gcaaaggcua ccuaucagca uuacgcaccg gcugguacac aucaguaaua      240

acaauagaac uauccaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguaaaa      300

uuaauaaaac aagaacucga caaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaaguacuc cagccaccaa caacagagca agaagagaau uaccacgauu uaugaacuac      420

acacuaaaca augcaaaaaa aacaaacgua acacuaucaa aaaaacguaa acgcagauuc      480

uuaggcuucc uccuaggugu aggcucagca aucgccucag gaguggcagu uuguaaagua      540

cuacaccuag aaggagaagu aaacaaaauc aaaucugccc uuuuaucgac aaacaaagca      600

guaguaucgu uauccaaugg agucucagua uugacauuca aaguauuaga ccuaaaaaau      660

uauauagaua aacaacucuu accuaucuua aauaaacaaa gcugcucaau aaguaacaua      720

gaaaccguaa uagaauuuca acaaaaaaac aauagacucc uugagaucac ucgagaauuu      780

ucaguaaacg cagguguaac aacaccagua agcacauaca ugcuaacaaa uagugaacua      840

uuaucucuaa uuaacgauau gcccauaacc aacgaucaaa aaaaacucau gaguaacaac      900

guacaaauag uaagacaaca auccuauagc auaaugugca uuauaaaaga agaaguacua      960

gcauauguag uccaacuacc acuauacggc guaauagaca caccaugcug gaaacuacac     1020

accucacccc uaugcacaac aaauacaaaa gaaggaucaa acauaugcuu aaccaggaca     1080

gacagaggcu gguacugcga uaacgcagga ucuguuucau ucuuccccca agcagaaaca     1140

ugcaaaguac aaucaaacag aguauuuugu gauaccauga acucacucac auuaccaucc     1200

gaagucaacc ucugcaacgu agacauauuc aaccccaaau acgacugcaa aauaaugacc     1260

ucaaaaacag auguaucauc aucaguaauc acaucacuag gagcuaucgu aucuuguuau     1320

ggaaaaacaa aaugcacagc auccaacaaa aacagaggaa uuaucaaaac auucucaaau     1380

ggaugugacu auguaucaaa caaaggagua gacaccguaa gcguaggcaa uacacuauau     1440

uacguaaaua aacaagaagg aaaaucacua uacguaaaag gugaaccaau aauaaacuuc     1500

uaugaccccc uaguauuccc aucagaugaa uuugacgcaa gcauaucaca agucaacgaa     1560

aaaauaaacc aaucacuggc auucauucgc aaaucagaug aacuucucca caacguaaac     1620

gcugguaaaa gcacuacaaa cauaaugaua acaacaauca ucauugucau aauaguuauu     1680

cuauuaucac uaaucgcagu aggauuacua cuauacugua aagcgaggua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1459
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1459
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccacaau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgaaccg gcugguacac cuccgugauc      240

accaucgagc ugucaaacau caaggagaac aagugcaacg ggaccgaugc caagguuaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccacuc cggcaaccaa caaccgcgcc aggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaaugug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccuaggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

uugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

gugguaagcc ucuccaacgg cgucagcguu cugaccuuca aggugcugga ccucaagaac      660

uauaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cucaaacauc      720

gaaacgguga uugaguucca gcagaagaac aaccggcucc uggaaaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cuaucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga agaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcacaac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccucu     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagacag acgugagcuc cagcgugauc acaucccugg gggccaucgu cagcugcuac     1320

ggcaagacua aguguacugc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacguuaaua agcaggaggg caagagccuc uacgugaaag gggagcccau cauuaacuuc     1500

uacgacccac ugguuuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgugauu     1680

cugcuguccc ucaucgccgu ggggcugcug cuuuacugca aggcccggug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1460
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1460
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1461
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1461
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1462
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1462
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1463
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1463
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1464
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1464
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1465
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1465
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1466
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1466
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaau gcuauuacca caauacuuac ugcuguaacc      180

uucugcuuug ccucuggcca aaacauaaca gaagaauuuu aucaaucaac uugcuccgcu      240

guaagcaaag gcuaccuauc agcauuacgc accggcuggu acacaucagu aauaacaaua      300

gaacuaucca acauaaaaga aaauaaaugc aacggaacag acgcaaaagu aaaauuaaua      360

aaacaagaac ucgacaaaua caaaaacgca guaacagaau uacaacuacu aaugcaaagu      420

acuccagcca ccaacaacag agcaagaaga gaauuaccac gauuuaugaa cuacacacua      480

aacaaugcaa aaaaaacaaa cguaacacua ucaaaaaaac guaaacgcag auucuuaggc      540

uuccuccuag guguaggcuc agcaaucgcc ucaggagugg caguuuguaa aguacuacac      600

cuagaaggag aaguaaacaa aaucaaaucu gcccuuuuau cgacaaacaa agcaguagua      660

ucguuaucca auggagucuc aguauugaca uucaaaguau uagaccuaaa aaauuauaua      720

gauaaacaac ucuuaccuau cuuaaauaaa caaagcugcu caauaaguaa cauagaaacc      780

guaauagaau uucaacaaaa aaacaauaga cuccuugaga ucacucgaga auuuucagua      840

aacgcaggug uaacaacacc aguaagcaca uacaugcuaa caaauaguga acuauuaucu      900

cuaauuaacg auaugcccau aaccaacgau caaaaaaaac ucaugaguaa caacguacaa      960

auaguaagac aacaauccua uagcauaaug ugcauuauaa aagaagaagu acuagcauau     1020

guaguccaac uaccacuaua cggcguaaua gacacaccau gcuggaaacu acacaccuca     1080

ccccuaugca caacaaauac aaaagaagga ucaaacauau gcuuaaccag gacagacaga     1140

ggcugguacu gcgauaacgc aggaucuguu ucauucuucc cccaagcaga aacaugcaaa     1200

guacaaucaa acagaguauu uugugauacc augaacucac ucacauuacc auccgaaguc     1260

aaccucugca acguagacau auucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1320

acagauguau caucaucagu aaucacauca cuaggagcua ucguaucuug uuauggaaaa     1380

acaaaaugca cagcauccaa caaaaacaga ggaauuauca aaacauucuc aaauggaugu     1440

gacuauguau caaacaaagg aguagacacc guaagcguag gcaauacacu auauuacgua     1500

aauaaacaag aaggaaaauc acuauacgua aaaggugaac caauaauaaa cuucuaugac     1560

ccccuaguau ucccaucaga ugaauuugac gcaagcauau cacaagucaa cgaaaaaaua     1620

aaccaaucac uggcauucau ucgcaaauca gaugaacuuc uccacaacgu aaacgcuggu     1680

aaaagcacua caaacauaau gauaacaaca aucaucauug ucauaauagu uauucuauua     1740

ucacuaaucg caguaggauu acuacuauac uguaaagcga gguaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1467
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1467
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca caauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcga accggcuggu acaccuccgu gaucaccauc      300

gagcugucaa acaucaagga gaacaagugc aacgggaccg augccaaggu uaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acuccggcaa ccaacaaccg cgccaggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa ugugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccuag gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa gguguugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggua      660

agccucucca acggcgucag cguucugacc uucaaggugc uggaccucaa gaacuauauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucucaaa caucgaaacg      780

gugauugagu uccagcagaa gaacaaccgg cuccuggaaa ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccuaucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaagaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca caaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cucugaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

acagacguga gcuccagcgu gaucacaucc cugggggcca ucgucagcug cuacggcaag     1380

acuaagugua cugccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacguu     1500

aauaagcagg agggcaagag ccucuacgug aaaggggagc ccaucauuaa cuucuacgac     1560

ccacugguuu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauucugcug     1740

ucccucaucg ccguggggcu gcugcuuuac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  1468
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1468
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1469
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1469
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1470
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1470
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1471
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1471
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1472
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1472
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1473
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1473
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1474
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1474
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaaugcu      120

auuaccacaa uacuuacugc uguaaccuuc ugcuuugccu cuggccaaaa cauaacagaa      180

gaauuuuauc aaucaacuug cuccgcugua agcaaaggcu accuaucagc auuacgcacc      240

ggcugguaca caucaguaau aacaauagaa cuauccaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguaaa auuaauaaaa caagaacucg acaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaaguacu ccagccacca acaacagagc aagaagagaa      420

uuaccacgau uuaugaacua cacacuaaac aaugcaaaaa aaacaaacgu aacacuauca      480

aaaaaacgua aacgcagauu cuuaggcuuc cuccuaggug uaggcucagc aaucgccuca      540

ggaguggcag uuuguaaagu acuacaccua gaaggagaag uaaacaaaau caaaucugcc      600

cuuuuaucga caaacaaagc aguaguaucg uuauccaaug gagucucagu auugacauuc      660

aaaguauuag accuaaaaaa uuauauagau aaacaacucu uaccuaucuu aaauaaacaa      720

agcugcucaa uaaguaacau agaaaccgua auagaauuuc aacaaaaaaa caauagacuc      780

cuugagauca cucgagaauu uucaguaaac gcagguguaa caacaccagu aagcacauac      840

augcuaacaa auagugaacu auuaucucua auuaacgaua ugcccauaac caacgaucaa      900

aaaaaacuca ugaguaacaa cguacaaaua guaagacaac aauccuauag cauaaugugc      960

auuauaaaag aagaaguacu agcauaugua guccaacuac cacuauacgg cguaauagac     1020

acaccaugcu ggaaacuaca caccucaccc cuaugcacaa caaauacaaa agaaggauca     1080

aacauaugcu uaaccaggac agacagaggc ugguacugcg auaacgcagg aucuguuuca     1140

uucuuccccc aagcagaaac augcaaagua caaucaaaca gaguauuuug ugauaccaug     1200

aacucacuca cauuaccauc cgaagucaac cucugcaacg uagacauauu caaccccaaa     1260

uacgacugca aaauaaugac cucaaaaaca gauguaucau caucaguaau cacaucacua     1320

ggagcuaucg uaucuuguua uggaaaaaca aaaugcacag cauccaacaa aaacagagga     1380

auuaucaaaa cauucucaaa uggaugugac uauguaucaa acaaaggagu agacaccgua     1440

agcguaggca auacacuaua uuacguaaau aaacaagaag gaaaaucacu auacguaaaa     1500

ggugaaccaa uaauaaacuu cuaugacccc cuaguauucc caucagauga auuugacgca     1560

agcauaucac aagucaacga aaaaauaaac caaucacugg cauucauucg caaaucagau     1620

gaacuucucc acaacguaaa cgcugguaaa agcacuacaa acauaaugau aacaacaauc     1680

aucauuguca uaauaguuau ucuauuauca cuaaucgcag uaggauuacu acuauacugu     1740

aaagcgaggu aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1475
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1475
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacaa uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgaacc      240

ggcugguaca ccuccgugau caccaucgag cugucaaaca ucaaggagaa caagugcaac      300

gggaccgaug ccaagguuaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacu ccggcaacca acaaccgcgc caggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaaugu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuagggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu guugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cgugguaagc cucuccaacg gcgucagcgu ucugaccuuc      660

aaggugcugg accucaagaa cuauaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucucaaacau cgaaacggug auugaguucc agcagaagaa caaccggcuc      780

cuggaaauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccuaucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aagaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacaa ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccuc ugagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagaca gacgugagcu ccagcgugau cacaucccug     1320

ggggccaucg ucagcugcua cggcaagacu aaguguacug ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacguuaau aagcaggagg gcaagagccu cuacgugaaa     1500

ggggagccca ucauuaacuu cuacgaccca cugguuuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ucugcugucc cucaucgccg uggggcugcu gcuuuacugc     1740

aaggcccggu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1800

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1476
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1476
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1477
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1477
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1478
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1478
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1479
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1479
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1480
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1480
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1481
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1481
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1482
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1482
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaaugcu      120

auuaccacaa uacuuacugc uguaaccuuc ugcuuugccu cuggccaaaa cauaacagaa      180

gaauuuuauc aaucaacuug cuccgcugua agcaaaggcu accuaucagc auuacgcacc      240

ggcugguaca caucaguaau aacaauagaa cuauccaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguaaa auuaauaaaa caagaacucg acaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaaguacu ccagccacca acaacagagc aagaagagaa      420

uuaccacgau uuaugaacua cacacuaaac aaugcaaaaa aaacaaacgu aacacuauca      480

aaaaaacgua aacgcagauu cuuaggcuuc cuccuaggug uaggcucagc aaucgccuca      540

ggaguggcag uuuguaaagu acuacaccua gaaggagaag uaaacaaaau caaaucugcc      600

cuuuuaucga caaacaaagc aguaguaucg uuauccaaug gagucucagu auugacauuc      660

aaaguauuag accuaaaaaa uuauauagau aaacaacucu uaccuaucuu aaauaaacaa      720

agcugcucaa uaaguaacau agaaaccgua auagaauuuc aacaaaaaaa caauagacuc      780

cuugagauca cucgagaauu uucaguaaac gcagguguaa caacaccagu aagcacauac      840

augcuaacaa auagugaacu auuaucucua auuaacgaua ugcccauaac caacgaucaa      900

aaaaaacuca ugaguaacaa cguacaaaua guaagacaac aauccuauag cauaaugugc      960

auuauaaaag aagaaguacu agcauaugua guccaacuac cacuauacgg cguaauagac     1020

acaccaugcu ggaaacuaca caccucaccc cuaugcacaa caaauacaaa agaaggauca     1080

aacauaugcu uaaccaggac agacagaggc ugguacugcg auaacgcagg aucuguuuca     1140

uucuuccccc aagcagaaac augcaaagua caaucaaaca gaguauuuug ugauaccaug     1200

aacucacuca cauuaccauc cgaagucaac cucugcaacg uagacauauu caaccccaaa     1260

uacgacugca aaauaaugac cucaaaaaca gauguaucau caucaguaau cacaucacua     1320

ggagcuaucg uaucuuguua uggaaaaaca aaaugcacag cauccaacaa aaacagagga     1380

auuaucaaaa cauucucaaa uggaugugac uauguaucaa acaaaggagu agacaccgua     1440

agcguaggca auacacuaua uuacguaaau aaacaagaag gaaaaucacu auacguaaaa     1500

ggugaaccaa uaauaaacuu cuaugacccc cuaguauucc caucagauga auuugacgca     1560

agcauaucac aagucaacga aaaaauaaac caaucacugg cauucauucg caaaucagau     1620

gaacuucucc acaacguaaa cgcugguaaa agcacuacaa acauaaugau aacaacaauc     1680

aucauuguca uaauaguuau ucuauuauca cuaaucgcag uaggauuacu acuauacugu     1740

aaagcgaggu aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1483
<211>  2031
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1483
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacaa uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgaacc      240

ggcugguaca ccuccgugau caccaucgag cugucaaaca ucaaggagaa caagugcaac      300

gggaccgaug ccaagguuaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacu ccggcaacca acaaccgcgc caggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaaugu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuagggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu guugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cgugguaagc cucuccaacg gcgucagcgu ucugaccuuc      660

aaggugcugg accucaagaa cuauaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucucaaacau cgaaacggug auugaguucc agcagaagaa caaccggcuc      780

cuggaaauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccuaucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aagaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacaa ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccuc ugagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagaca gacgugagcu ccagcgugau cacaucccug     1320

ggggccaucg ucagcugcua cggcaagacu aaguguacug ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacguuaau aagcaggagg gcaagagccu cuacgugaaa     1500

ggggagccca ucauuaacuu cuacgaccca cugguuuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ucugcugucc cucaucgccg uggggcugcu gcuuuacugc     1740

aaggcccggu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1800

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1860

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1980

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2031


<210>  1484
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1484
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1485
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1485
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1486
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1486
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1487
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1487
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1488
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1488
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1489
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1489
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1490
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1490
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaaugcu      120

auuaccacaa uacuuacugc uguaaccuuc ugcuuugccu cuggccaaaa cauaacagaa      180

gaauuuuauc aaucaacuug cuccgcugua agcaaaggcu accuaucagc auuacgcacc      240

ggcugguaca caucaguaau aacaauagaa cuauccaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguaaa auuaauaaaa caagaacucg acaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaaguacu ccagccacca acaacagagc aagaagagaa      420

uuaccacgau uuaugaacua cacacuaaac aaugcaaaaa aaacaaacgu aacacuauca      480

aaaaaacgua aacgcagauu cuuaggcuuc cuccuaggug uaggcucagc aaucgccuca      540

ggaguggcag uuuguaaagu acuacaccua gaaggagaag uaaacaaaau caaaucugcc      600

cuuuuaucga caaacaaagc aguaguaucg uuauccaaug gagucucagu auugacauuc      660

aaaguauuag accuaaaaaa uuauauagau aaacaacucu uaccuaucuu aaauaaacaa      720

agcugcucaa uaaguaacau agaaaccgua auagaauuuc aacaaaaaaa caauagacuc      780

cuugagauca cucgagaauu uucaguaaac gcagguguaa caacaccagu aagcacauac      840

augcuaacaa auagugaacu auuaucucua auuaacgaua ugcccauaac caacgaucaa      900

aaaaaacuca ugaguaacaa cguacaaaua guaagacaac aauccuauag cauaaugugc      960

auuauaaaag aagaaguacu agcauaugua guccaacuac cacuauacgg cguaauagac     1020

acaccaugcu ggaaacuaca caccucaccc cuaugcacaa caaauacaaa agaaggauca     1080

aacauaugcu uaaccaggac agacagaggc ugguacugcg auaacgcagg aucuguuuca     1140

uucuuccccc aagcagaaac augcaaagua caaucaaaca gaguauuuug ugauaccaug     1200

aacucacuca cauuaccauc cgaagucaac cucugcaacg uagacauauu caaccccaaa     1260

uacgacugca aaauaaugac cucaaaaaca gauguaucau caucaguaau cacaucacua     1320

ggagcuaucg uaucuuguua uggaaaaaca aaaugcacag cauccaacaa aaacagagga     1380

auuaucaaaa cauucucaaa uggaugugac uauguaucaa acaaaggagu agacaccgua     1440

agcguaggca auacacuaua uuacguaaau aaacaagaag gaaaaucacu auacguaaaa     1500

ggugaaccaa uaauaaacuu cuaugacccc cuaguauucc caucagauga auuugacgca     1560

agcauaucac aagucaacga aaaaauaaac caaucacugg cauucauucg caaaucagau     1620

gaacuucucc acaacguaaa cgcugguaaa agcacuacaa acauaaugau aacaacaauc     1680

aucauuguca uaauaguuau ucuauuauca cuaaucgcag uaggauuacu acuauacugu     1740

aaagcgaggu aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1491
<211>  2247
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1491
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacaa uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgaacc      240

ggcugguaca ccuccgugau caccaucgag cugucaaaca ucaaggagaa caagugcaac      300

gggaccgaug ccaagguuaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacu ccggcaacca acaaccgcgc caggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaaugu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuagggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu guugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cgugguaagc cucuccaacg gcgucagcgu ucugaccuuc      660

aaggugcugg accucaagaa cuauaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucucaaacau cgaaacggug auugaguucc agcagaagaa caaccggcuc      780

cuggaaauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccuaucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aagaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacaa ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccuc ugagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagaca gacgugagcu ccagcgugau cacaucccug     1320

ggggccaucg ucagcugcua cggcaagacu aaguguacug ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacguuaau aagcaggagg gcaagagccu cuacgugaaa     1500

ggggagccca ucauuaacuu cuacgaccca cugguuuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ucugcugucc cucaucgccg uggggcugcu gcuuuacugc     1740

aaggcccggu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1800

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1860

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1920

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1980

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     2040

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     2100

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     2220

aaggcucuuu ucagagccac cagaauu                                         2247


<210>  1492
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1492
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaacca acaaccgcgc ccggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuggggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc      780

cuggagauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug     1320

ggggccaucg ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag     1500

ggggagccca ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguca ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc     1740

aaggcccggu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1493
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1493
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccacca acaaccgggc ccgccgggag      420

cugccgcgcu ucaugaacua cacccucaac aacgccaaga agacgaacgu gacccugagc      480

aagaagcgga agcgccgguu ccugggcuuc cuccuggggg ugggcuccgc gaucgccagc      540

ggcgucgccg ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caaguccgcc      600

cugcugagca ccaacaaggc cguggugucc cucagcaacg gcgucuccgu gcugaccuuc      660

aaggugcugg accucaagaa cuacaucgac aagcagcugc ugcccauccu caacaagcag      720

agcugcucca ucagcaacau cgagacgguc aucgaguucc agcagaagaa caaccgccug      780

cuggagauca cccgggaguu cuccgugaac gcggggguga ccacccccgu cagcacguac      840

augcucacca acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugcgccagc aguccuacag caucaugugc      960

aucaucaagg aggagguccu ggccuacgug gugcagcucc cgcuguacgg cgucaucgac     1020

acccccugcu ggaagcugca cacgagcccc cucugcacca ccaacaccaa ggaggggagc     1080

aacaucugcc ugacgcggac cgaccgcggc ugguacugcg acaacgccgg cuccgugagc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc ggguguucug cgacaccaug     1200

aacagccuga cgcucccguc cgaggugaac cugugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugucca gcuccgugau caccagccug     1320

ggggccaucg ucuccugcua cggcaagacg aagugcaccg cgagcaacaa gaaccgcggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccguc     1440

agcgugggga acacccucua cuacgugaac aagcaggagg gcaagucccu guacgucaag     1500

ggggagccca ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc     1560

uccaucagcc aggugaacga gaagaucaac cagucccucg ccuucauccg gaaguccgac     1620

gagcugcugc acaacgucaa cgccggcaag uccacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcucagc cugaucgccg ucgggcugcu ccuguacugc     1740

aaggcgcgcu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1494
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1494
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccacca acaaccgcgc ccgccgcgag      420

cucccccgcu ucaugaacua cacccucaac aacgccaaga agaccaacgu cacccucucc      480

aagaagcgca agcgccgcuu ccucggcuuc cuccucggcg ucggcuccgc caucgccucc      540

ggcgucgccg ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc      600

cuccucucca ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc      660

aagguccucg accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag      720

uccugcucca ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc      780

cucgagauca cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac      840

augcucacca acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag      900

aagaagcuca uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc      960

aucaucaagg aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac     1020

acccccugcu ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc     1080

aacaucugcc ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc     1140

uucuuccccc aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug     1200

aacucccuca cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc     1320

ggcgccaucg ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc     1380

aucaucaaga ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc     1440

uccgucggca acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag     1500

ggcgagccca ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc     1560

uccaucuccc aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac     1620

gagcuccucc acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc     1680

aucaucguca ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc     1740

aaggcccgcu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1495
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1495
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccacca acaauagggc ucggcgcgag      420

uugccucgau uuaugaacua cacgcucaau aacgcaaaga aaacuaaugu gacccugucg      480

aagaaacgua agagaagguu ccugggcuuu cucuuagggg ucggaucagc cauagcuagc      540

ggcguggccg uuuguaaggu gcugcaccuu gaaggugagg ucaacaaaau caagagugcg      600

uugcugucca caaauaaagc agugguaucu cuaagcaacg ggguuuccgu gcucacuuuc      660

aagguccugg accuuaaaaa uuauauugau aagcaacugu ugccaauccu caacaaacag      720

ucaugcagua uuagcaacau cgaaaccgug auagaguuuc agcagaagaa uaaccggcug      780

uuagagauua cacgcgaguu cucugugaau gccggaguca ccacgccggu uuccacuuac      840

augcugacaa acucagaacu ccuuagccug aucaaugaca ugcccauuac caacgaucaa      900

aagaaauuga ugaguaauaa cgugcagauc guaagacagc agucuuauuc caucaugugu      960

auuauaaagg aagaggugcu agcuuacguc gugcaacugc cucucuacgg cguuaucgac     1020

acuccaugcu ggaaacugca uacaagcccc cuuuguacca cgaauaccaa ggaaggcucg     1080

aacauuugcc ugacaaggac ugaucggggg ugguauugug acaaugccgg aucugugucc     1140

uuuuucccuc aggcagagac cugcaaaguc cagucaaacc gcguguuuug ugauacaaug     1200

aauaguuuga cucucccaag cgagguaaac cugugcaaug uugacaucuu caaccccaag     1260

uacgauugca agauaaugac cuccaaaaca gacgugucua gcucagucau uaccaguuua     1320

ggugcuaucg uguccuguua uggcaagacu aaaugcacgg ccagcaacaa gaaucgaggg     1380

aucauuaaaa cauuuucuaa cggaugugau uacgucucaa auaagggcgu ggacaccguu     1440

agugugggua acacucugua uuacguaaau aagcaagaag ggaaaagccu auaugucaag     1500

ggagagccua ucauuaacuu cuacgaccca cucguguucc cguccgauga auuugacgcg     1560

ucuauaucgc agguuaauga gaaaaucaac cagagccugg ccuucauuag aaaguccgau     1620

gaacuuuugc acaaugugaa cgcaggcaaa ucaaccacaa auaucaugau caccacuauu     1680

auaaucguca uuaucgugau ucugcucagu cugaucgcug uaggccuucu guuguacugc     1740

aaggccaggu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1496
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1496
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccacca acaacagagc cagaagagag      420

cugcccagau ucaugaacua cacccugaac aacgccaaga agaccaacgu gacccugagc      480

aagaagagaa agagaagauu ccugggcuuc cugcugggcg ugggcagcgc caucgccagc      540

ggcguggccg ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc      600

cugcugagca ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc      660

aaggugcugg accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcagca ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug      780

cuggagauca ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac      840

augcugacca acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag      900

aagaagcuga ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc      960

aucaucaagg aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac     1020

acccccugcu ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc     1080

aacaucugcc ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc     1140

uucuuccccc aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug     1200

aacagccuga cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag     1260

uacgacugca agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug     1320

ggcgccaucg ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc     1380

aucaucaaga ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

agcgugggca acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag     1500

ggcgagccca ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc     1560

agcaucagcc aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac     1620

gagcugcugc acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc     1740

aaggccagau gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1497
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1497
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacaa acaaucgggc ucgcagagag      420

cucccucggu uuaugaacua cacccugaau aacgccaaga aaacaaaugu cacccuuucu      480

aagaaacgca agagacgguu ccugggguuu cuccugggag ugggcagcgc gauugccucc      540

gggguugcug uguguaaggu ccuucaccug gaaggagagg ugaacaaaau caagagcgcc      600

cuccugucua cgaauaaagc uguugugucc cugagcaacg gcgucucugu gcucacauuc      660

aaggugcugg accuuaaaaa uuauauugau aagcaacugc ucccgauccu gaacaaacag      720

uccugcagca uuucuaacau cgaaaccguc auugaguuuc agcagaagaa uaaccgccuu      780

cuggagauca caagagaauu uuccguuaau gccggcguga ccacccccgu gagcacauac      840

augcucacga acuccgagcu gcugucucuc aucaaugaca ugccuauuac caacgaucaa      900

aagaaacuga ugagcaauaa cguccagauc gugcggcagc aguccuauag cauuaugugu      960

aucauuaagg aagagguucu ugcguacgug guccaacugc cccucuacgg ggugaucgac     1020

acaccuugcu ggaaacugca uaccucuccc cuuuguacaa ccaauacgaa ggaaggaucc     1080

aacaucugcc ugacacgcac cgauagaggc ugguauugug acaaugccgg gagcguuucu     1140

uucuucccuc aggcugagac cugcaaagug cagagcaacc gggucuuuug ugauacaaug     1200

aacucccuca cccugccguc ugaggugaau cugugcaaug ucgacauuuu caaccccaag     1260

uacgauugca agaucaugac aagcaaaacg gacgugucca gcucuguuau uaccucccuc     1320

ggagccaucg ugagcuguua uggcaagaca aaaugcaccg cuucuaacaa gaaucgcggg     1380

auuaucaaaa cauuuuccaa cggaugugau uacgucagca auaagggcgu ggacaccguu     1440

uccgugggca acacgcugua uuacgucaau aagcaagaag ggaaaucucu uuaugugaag     1500

ggagagccua ucauuaacuu cuacgacccc cugguguucc cuagcgauga auuugacgcc     1560

uccaucucuc agguuaauga gaaaauuaac cagagccucg ccuucaucag aaaguccgau     1620

gaacugcugc acaaugucaa cgcuggcaaa agcaccacaa auauuaugau caccacaauu     1680

aucaucguga uuaucgugau ucuucucucu cugaucgcgg ucgggcugcu ccuguacugc     1740

aaggcccggu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1498
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1498
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaaugcu      120

auuaccacaa uacuuacugc uguaaccuuc ugcuuugccu cuggccaaaa cauaacagaa      180

gaauuuuauc aaucaacuug cuccgcugua agcaaaggcu accuaucagc auuacgcacc      240

ggcugguaca caucaguaau aacaauagaa cuauccaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguaaa auuaauaaaa caagaacucg acaaauacaa aaacgcagua      360

acagaauuac aacuacuaau gcaaaguacu ccagccacca acaacagagc aagaagagaa      420

uuaccacgau uuaugaacua cacacuaaac aaugcaaaaa aaacaaacgu aacacuauca      480

aaaaaacgua aacgcagauu cuuaggcuuc cuccuaggug uaggcucagc aaucgccuca      540

ggaguggcag uuuguaaagu acuacaccua gaaggagaag uaaacaaaau caaaucugcc      600

cuuuuaucga caaacaaagc aguaguaucg uuauccaaug gagucucagu auugacauuc      660

aaaguauuag accuaaaaaa uuauauagau aaacaacucu uaccuaucuu aaauaaacaa      720

agcugcucaa uaaguaacau agaaaccgua auagaauuuc aacaaaaaaa caauagacuc      780

cuugagauca cucgagaauu uucaguaaac gcagguguaa caacaccagu aagcacauac      840

augcuaacaa auagugaacu auuaucucua auuaacgaua ugcccauaac caacgaucaa      900

aaaaaacuca ugaguaacaa cguacaaaua guaagacaac aauccuauag cauaaugugc      960

auuauaaaag aagaaguacu agcauaugua guccaacuac cacuauacgg cguaauagac     1020

acaccaugcu ggaaacuaca caccucaccc cuaugcacaa caaauacaaa agaaggauca     1080

aacauaugcu uaaccaggac agacagaggc ugguacugcg auaacgcagg aucuguuuca     1140

uucuuccccc aagcagaaac augcaaagua caaucaaaca gaguauuuug ugauaccaug     1200

aacucacuca cauuaccauc cgaagucaac cucugcaacg uagacauauu caaccccaaa     1260

uacgacugca aaauaaugac cucaaaaaca gauguaucau caucaguaau cacaucacua     1320

ggagcuaucg uaucuuguua uggaaaaaca aaaugcacag cauccaacaa aaacagagga     1380

auuaucaaaa cauucucaaa uggaugugac uauguaucaa acaaaggagu agacaccgua     1440

agcguaggca auacacuaua uuacguaaau aaacaagaag gaaaaucacu auacguaaaa     1500

ggugaaccaa uaauaaacuu cuaugacccc cuaguauucc caucagauga auuugacgca     1560

agcauaucac aagucaacga aaaaauaaac caaucacugg cauucauucg caaaucagau     1620

gaacuucucc acaacguaaa cgcugguaaa agcacuacaa acauaaugau aacaacaauc     1680

aucauuguca uaauaguuau ucuauuauca cuaaucgcag uaggauuacu acuauacugu     1740

aaagcgaggu aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1499
<211>  2027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1499
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacaa uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgaacc      240

ggcugguaca ccuccgugau caccaucgag cugucaaaca ucaaggagaa caagugcaac      300

gggaccgaug ccaagguuaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacu ccggcaacca acaaccgcgc caggcgcgag      420

cugccccggu ucaugaacua cacccucaac aacgccaaga agacgaaugu gacccugagc      480

aagaagcgca agcggcgcuu ccugggcuuc cuccuagggg ugggcuccgc caucgcgagc      540

ggcgucgccg ugugcaaggu guugcaccuc gagggggagg ucaacaagau caagagcgcc      600

cugcugucca ccaacaaggc cgugguaagc cucuccaacg gcgucagcgu ucugaccuuc      660

aaggugcugg accucaagaa cuauaucgac aagcagcugc ugcccauccu gaacaagcag      720

agcugcucca ucucaaacau cgaaacggug auugaguucc agcagaagaa caaccggcuc      780

cuggaaauca cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac      840

augcugacca acagcgagcu ccuaucccug aucaacgaca ugccgaucac caacgaccag      900

aagaagcuca ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc      960

aucaucaagg aagaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac     1020

acccccugcu ggaagcugca cacgagcccc cugugcacaa ccaacaccaa ggaggggucc     1080

aacaucugcc ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc     1140

uucuucccgc aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug     1200

aacucccuga cgcugcccuc ugagguaaac cucugcaacg ucgacaucuu caaccccaag     1260

uacgacugca agaucaugac cuccaagaca gacgugagcu ccagcgugau cacaucccug     1320

ggggccaucg ucagcugcua cggcaagacu aaguguacug ccagcaacaa gaaccggggg     1380

aucaucaaga ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug     1440

uccgucggga acacccugua cuacguuaau aagcaggagg gcaagagccu cuacgugaaa     1500

ggggagccca ucauuaacuu cuacgaccca cugguuuucc ccuccgacga guucgacgcg     1560

agcaucuccc aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac     1620

gagcugcucc acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc     1680

aucaucguga ucaucgugau ucugcugucc cucaucgccg uggggcugcu gcuuuacugc     1740

aaggcccggu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1800

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1860

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1980

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   2027


<210>  1500
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1500
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1501
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1501
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1502
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1502
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1503
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1503
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1504
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1504
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1505
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1505
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1506
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1506
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaaugcuauu accacaauac      120

uuacugcugu aaccuucugc uuugccucug gccaaaacau aacagaagaa uuuuaucaau      180

caacuugcuc cgcuguaagc aaaggcuacc uaucagcauu acgcaccggc ugguacacau      240

caguaauaac aauagaacua uccaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguaaaauu aauaaaacaa gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aaguacucca gccaccaaca acagagcaag aagagaauua ccacgauuua      420

ugaacuacac acuaaacaau gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac      480

gcagauucuu aggcuuccuc cuagguguag gcucagcaau cgccucagga guggcaguuu      540

guaaaguacu acaccuagaa ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa      600

acaaagcagu aguaucguua uccaauggag ucucaguauu gacauucaaa guauuagacc      660

uaaaaaauua uauagauaaa caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa      720

guaacauaga aaccguaaua gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc      780

gagaauuuuc aguaaacgca gguguaacaa caccaguaag cacauacaug cuaacaaaua      840

gugaacuauu aucucuaauu aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga      900

guaacaacgu acaaauagua agacaacaau ccuauagcau aaugugcauu auaaaagaag      960

aaguacuagc auauguaguc caacuaccac uauacggcgu aauagacaca ccaugcugga     1020

aacuacacac cucaccccua ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa     1080

ccaggacaga cagaggcugg uacugcgaua acgcaggauc uguuucauuc uucccccaag     1140

cagaaacaug caaaguacaa ucaaacagag uauuuuguga uaccaugaac ucacucacau     1200

uaccauccga agucaaccuc ugcaacguag acauauucaa ccccaaauac gacugcaaaa     1260

uaaugaccuc aaaaacagau guaucaucau caguaaucac aucacuagga gcuaucguau     1320

cuuguuaugg aaaaacaaaa ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau     1380

ucucaaaugg augugacuau guaucaaaca aaggaguaga caccguaagc guaggcaaua     1440

cacuauauua cguaaauaaa caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa     1500

uaaacuucua ugacccccua guauucccau cagaugaauu ugacgcaagc auaucacaag     1560

ucaacgaaaa aauaaaccaa ucacuggcau ucauucgcaa aucagaugaa cuucuccaca     1620

acguaaacgc ugguaaaagc acuacaaaca uaaugauaac aacaaucauc auugucauaa     1680

uaguuauucu auuaucacua aucgcaguag gauuacuacu auacuguaaa gcgagguaag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1507
<211>  2018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1507
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accacaaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgaaccggc ugguacaccu      240

ccgugaucac caucgagcug ucaaacauca aggagaacaa gugcaacggg accgaugcca      300

agguuaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccacuccg gcaaccaaca accgcgccag gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaaugugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cuaggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaagguguu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu gguaagccuc uccaacggcg ucagcguucu gaccuucaag gugcuggacc      660

ucaagaacua uaucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccaucu      720

caaacaucga aacggugauu gaguuccagc agaagaacaa ccggcuccug gaaaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu aucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggaag      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcacaacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccucuga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagacagac gugagcucca gcgugaucac aucccugggg gccaucguca     1320

gcugcuacgg caagacuaag uguacugcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cguuaauaag caggagggca agagccucua cgugaaaggg gagcccauca     1500

uuaacuucua cgacccacug guuuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauucu gcugucccuc aucgccgugg ggcugcugcu uuacugcaag gcccggugag     1740

gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca ggauggugaa     1800

gggggaccug guacccagug auccccaccc caggauccua aaucaugacu uaccugcuaa     1860

uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1980

cccccccccc aaaggcucuu uucagagcca ccagaauu                             2018


<210>  1508
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1508
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1509
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1509
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccaaca accgggcccg ccgggagcug ccgcgcuuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcggaagc      480

gccgguuccu gggcuuccuc cugggggugg gcuccgcgau cgccagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa guccgcccug cugagcacca      600

acaaggccgu ggugucccuc agcaacggcg ucuccgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccucaa caagcagagc ugcuccauca      720

gcaacaucga gacggucauc gaguuccagc agaagaacaa ccgccugcug gagaucaccc      780

gggaguucuc cgugaacgcg ggggugacca cccccgucag cacguacaug cucaccaaca      840

gcgagcugcu gucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug cgccagcagu ccuacagcau caugugcauc aucaaggagg      960

agguccuggc cuacguggug cagcucccgc uguacggcgu caucgacacc cccugcugga     1020

agcugcacac gagcccccuc ugcaccacca acaccaagga ggggagcaac aucugccuga     1080

cgcggaccga ccgcggcugg uacugcgaca acgccggcuc cgugagcuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccggg uguucugcga caccaugaac agccugacgc     1200

ucccguccga ggugaaccug ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac guguccagcu ccgugaucac cagccugggg gccaucgucu     1320

ccugcuacgg caagacgaag ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgucagc guggggaaca     1440

cccucuacua cgugaacaag caggagggca agucccugua cgucaagggg gagcccauca     1500

ucaacuucua cgacccccug guguucccga gcgacgaguu cgacgccucc aucagccagg     1560

ugaacgagaa gaucaaccag ucccucgccu ucauccggaa guccgacgag cugcugcaca     1620

acgucaacgc cggcaagucc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcucagccug aucgccgucg ggcugcuccu guacugcaag gcgcgcugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1510
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1510
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca      420

ugaacuacac ccucaacaac gccaagaaga ccaacgucac ccucuccaag aagcgcaagc      480

gccgcuuccu cggcuuccuc cucggcgucg gcuccgccau cgccuccggc gucgccgucu      540

gcaagguccu ccaccucgag ggcgagguca acaagaucaa guccgcccuc cucuccacca      600

acaaggccgu cgucucccuc uccaacggcg ucuccguccu caccuucaag guccucgacc      660

ucaagaacua caucgacaag cagcuccucc ccauccucaa caagcagucc ugcuccaucu      720

ccaacaucga gaccgucauc gaguuccagc agaagaacaa ccgccuccuc gagaucaccc      780

gcgaguucuc cgucaacgcc ggcgucacca cccccgucuc caccuacaug cucaccaacu      840

ccgagcuccu cucccucauc aacgacaugc ccaucaccaa cgaccagaag aagcucaugu      900

ccaacaacgu ccagaucguc cgccagcagu ccuacuccau caugugcauc aucaaggagg      960

agguccucgc cuacgucguc cagcuccccc ucuacggcgu caucgacacc cccugcugga     1020

agcuccacac cuccccccuc ugcaccacca acaccaagga gggcuccaac aucugccuca     1080

cccgcaccga ccgcggcugg uacugcgaca acgccggcuc cgucuccuuc uucccccagg     1140

ccgagaccug caagguccag uccaaccgcg ucuucugcga caccaugaac ucccucaccc     1200

uccccuccga ggucaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gucuccuccu ccgucaucac cucccucggc gccaucgucu     1320

ccugcuacgg caagaccaag ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu     1380

ucuccaacgg cugcgacuac gucuccaaca agggcgucga caccgucucc gucggcaaca     1440

cccucuacua cgucaacaag caggagggca agucccucua cgucaagggc gagcccauca     1500

ucaacuucua cgacccccuc gucuuccccu ccgacgaguu cgacgccucc aucucccagg     1560

ucaacgagaa gaucaaccag ucccucgccu ucauccgcaa guccgacgag cuccuccaca     1620

acgucaacgc cggcaagucc accaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgucauccu ccucucccuc aucgccgucg gccuccuccu cuacugcaag gcccgcugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1511
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1511
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccaaca auagggcucg gcgcgaguug ccucgauuua      420

ugaacuacac gcucaauaac gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga      480

gaagguuccu gggcuuucuc uuaggggucg gaucagccau agcuagcggc guggccguuu      540

guaaggugcu gcaccuugaa ggugagguca acaaaaucaa gagugcguug cuguccacaa      600

auaaagcagu gguaucucua agcaacgggg uuuccgugcu cacuuucaag guccuggacc      660

uuaaaaauua uauugauaag caacuguugc caauccucaa caaacaguca ugcaguauua      720

gcaacaucga aaccgugaua gaguuucagc agaagaauaa ccggcuguua gagauuacac      780

gcgaguucuc ugugaaugcc ggagucacca cgccgguuuc cacuuacaug cugacaaacu      840

cagaacuccu uagccugauc aaugacaugc ccauuaccaa cgaucaaaag aaauugauga      900

guaauaacgu gcagaucgua agacagcagu cuuauuccau cauguguauu auaaaggaag      960

aggugcuagc uuacgucgug caacugccuc ucuacggcgu uaucgacacu ccaugcugga     1020

aacugcauac aagcccccuu uguaccacga auaccaagga aggcucgaac auuugccuga     1080

caaggacuga ucgggggugg uauugugaca augccggauc uguguccuuu uucccucagg     1140

cagagaccug caaaguccag ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc     1200

ucccaagcga gguaaaccug ugcaauguug acaucuucaa ccccaaguac gauugcaaga     1260

uaaugaccuc caaaacagac gugucuagcu cagucauuac caguuuaggu gcuaucgugu     1320

ccuguuaugg caagacuaaa ugcacggcca gcaacaagaa ucgagggauc auuaaaacau     1380

uuucuaacgg augugauuac gucucaaaua agggcgugga caccguuagu guggguaaca     1440

cucuguauua cguaaauaag caagaaggga aaagccuaua ugucaaggga gagccuauca     1500

uuaacuucua cgacccacuc guguucccgu ccgaugaauu ugacgcgucu auaucgcagg     1560

uuaaugagaa aaucaaccag agccuggccu ucauuagaaa guccgaugaa cuuuugcaca     1620

augugaacgc aggcaaauca accacaaaua ucaugaucac cacuauuaua aucgucauua     1680

ucgugauucu gcucagucug aucgcuguag gccuucuguu guacugcaag gccaggugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1512
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1512
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccaaca acagagccag aagagagcug cccagauuca      420

ugaacuacac ccugaacaac gccaagaaga ccaacgugac ccugagcaag aagagaaaga      480

gaagauuccu gggcuuccug cugggcgugg gcagcgccau cgccagcggc guggccgugu      540

gcaaggugcu gcaccuggag ggcgagguga acaagaucaa gagcgcccug cugagcacca      600

acaaggccgu ggugagccug agcaacggcg ugagcgugcu gaccuucaag gugcuggacc      660

ugaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcagcauca      720

gcaacaucga gaccgugauc gaguuccagc agaagaacaa cagacugcug gagaucacca      780

gagaguucag cgugaacgcc ggcgugacca cccccgugag caccuacaug cugaccaaca      840

gcgagcugcu gagccugauc aacgacaugc ccaucaccaa cgaccagaag aagcugauga      900

gcaacaacgu gcagaucgug agacagcaga gcuacagcau caugugcauc aucaaggagg      960

aggugcuggc cuacguggug cagcugcccc uguacggcgu gaucgacacc cccugcugga     1020

agcugcacac cagcccccug ugcaccacca acaccaagga gggcagcaac aucugccuga     1080

ccagaaccga cagaggcugg uacugcgaca acgccggcag cgugagcuuc uucccccagg     1140

ccgagaccug caaggugcag agcaacagag uguucugcga caccaugaac agccugaccc     1200

ugcccagcga ggugaaccug ugcaacgugg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccag caagaccgac gugagcagca gcgugaucac cagccugggc gccaucguga     1320

gcugcuacgg caagaccaag ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu     1380

ucagcaacgg cugcgacuac gugagcaaca agggcgugga caccgugagc gugggcaaca     1440

cccuguacua cgugaacaag caggagggca agagccugua cgugaagggc gagcccauca     1500

ucaacuucua cgacccccug guguucccca gcgacgaguu cgacgccagc aucagccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucaucagaaa gagcgacgag cugcugcaca     1620

acgugaacgc cggcaagagc accaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauccu gcugagccug aucgccgugg gccugcugcu guacugcaag gccagaugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1513
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1513
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacaaaca aucgggcucg cagagagcuc ccucgguuua      420

ugaacuacac ccugaauaac gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga      480

gacgguuccu gggguuucuc cugggagugg gcagcgcgau ugccuccggg guugcugugu      540

guaagguccu ucaccuggaa ggagagguga acaaaaucaa gagcgcccuc cugucuacga      600

auaaagcugu ugugucccug agcaacggcg ucucugugcu cacauucaag gugcuggacc      660

uuaaaaauua uauugauaag caacugcucc cgauccugaa caaacagucc ugcagcauuu      720

cuaacaucga aaccgucauu gaguuucagc agaagaauaa ccgccuucug gagaucacaa      780

gagaauuuuc cguuaaugcc ggcgugacca cccccgugag cacauacaug cucacgaacu      840

ccgagcugcu gucucucauc aaugacaugc cuauuaccaa cgaucaaaag aaacugauga      900

gcaauaacgu ccagaucgug cggcagcagu ccuauagcau uauguguauc auuaaggaag      960

agguucuugc guacgugguc caacugcccc ucuacggggu gaucgacaca ccuugcugga     1020

aacugcauac cucuccccuu uguacaacca auacgaagga aggauccaac aucugccuga     1080

cacgcaccga uagaggcugg uauugugaca augccgggag cguuucuuuc uucccucagg     1140

cugagaccug caaagugcag agcaaccggg ucuuuuguga uacaaugaac ucccucaccc     1200

ugccgucuga ggugaaucug ugcaaugucg acauuuucaa ccccaaguac gauugcaaga     1260

ucaugacaag caaaacggac guguccagcu cuguuauuac cucccucgga gccaucguga     1320

gcuguuaugg caagacaaaa ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau     1380

uuuccaacgg augugauuac gucagcaaua agggcgugga caccguuucc gugggcaaca     1440

cgcuguauua cgucaauaag caagaaggga aaucucuuua ugugaaggga gagccuauca     1500

uuaacuucua cgacccccug guguucccua gcgaugaauu ugacgccucc aucucucagg     1560

uuaaugagaa aauuaaccag agccucgccu ucaucagaaa guccgaugaa cugcugcaca     1620

augucaacgc uggcaaaagc accacaaaua uuaugaucac cacaauuauc aucgugauua     1680

ucgugauucu ucucucucug aucgcggucg ggcugcuccu guacugcaag gcccggugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1514
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1514
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaaugcuauu accacaauac      120

uuacugcugu aaccuucugc uuugccucug gccaaaacau aacagaagaa uuuuaucaau      180

caacuugcuc cgcuguaagc aaaggcuacc uaucagcauu acgcaccggc ugguacacau      240

caguaauaac aauagaacua uccaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguaaaauu aauaaaacaa gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac      360

uacuaaugca aaguacucca gccaccaaca acagagcaag aagagaauua ccacgauuua      420

ugaacuacac acuaaacaau gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac      480

gcagauucuu aggcuuccuc cuagguguag gcucagcaau cgccucagga guggcaguuu      540

guaaaguacu acaccuagaa ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa      600

acaaagcagu aguaucguua uccaauggag ucucaguauu gacauucaaa guauuagacc      660

uaaaaaauua uauagauaaa caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa      720

guaacauaga aaccguaaua gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc      780

gagaauuuuc aguaaacgca gguguaacaa caccaguaag cacauacaug cuaacaaaua      840

gugaacuauu aucucuaauu aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga      900

guaacaacgu acaaauagua agacaacaau ccuauagcau aaugugcauu auaaaagaag      960

aaguacuagc auauguaguc caacuaccac uauacggcgu aauagacaca ccaugcugga     1020

aacuacacac cucaccccua ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa     1080

ccaggacaga cagaggcugg uacugcgaua acgcaggauc uguuucauuc uucccccaag     1140

cagaaacaug caaaguacaa ucaaacagag uauuuuguga uaccaugaac ucacucacau     1200

uaccauccga agucaaccuc ugcaacguag acauauucaa ccccaaauac gacugcaaaa     1260

uaaugaccuc aaaaacagau guaucaucau caguaaucac aucacuagga gcuaucguau     1320

cuuguuaugg aaaaacaaaa ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau     1380

ucucaaaugg augugacuau guaucaaaca aaggaguaga caccguaagc guaggcaaua     1440

cacuauauua cguaaauaaa caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa     1500

uaaacuucua ugacccccua guauucccau cagaugaauu ugacgcaagc auaucacaag     1560

ucaacgaaaa aauaaaccaa ucacuggcau ucauucgcaa aucagaugaa cuucuccaca     1620

acguaaacgc ugguaaaagc acuacaaaca uaaugauaac aacaaucauc auugucauaa     1680

uaguuauucu auuaucacua aucgcaguag gauuacuacu auacuguaaa gcgagguaag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1515
<211>  2234
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1515
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accacaaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgaaccggc ugguacaccu      240

ccgugaucac caucgagcug ucaaacauca aggagaacaa gugcaacggg accgaugcca      300

agguuaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccacuccg gcaaccaaca accgcgccag gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaaugugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cuaggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaagguguu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu gguaagccuc uccaacggcg ucagcguucu gaccuucaag gugcuggacc      660

ucaagaacua uaucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccaucu      720

caaacaucga aacggugauu gaguuccagc agaagaacaa ccggcuccug gaaaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu aucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggaag      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcacaacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccucuga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagacagac gugagcucca gcgugaucac aucccugggg gccaucguca     1320

gcugcuacgg caagacuaag uguacugcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cguuaauaag caggagggca agagccucua cgugaaaggg gagcccauca     1500

uuaacuucua cgacccacug guuuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgugauca     1680

ucgugauucu gcugucccuc aucgccgugg ggcugcugcu uuacugcaag gcccggugag     1740

gacuagugaa gggaacaccc aaauuuaauu cagccuuaag cacaauuaau uaagagugaa     1800

acguaauugu acaagcaguu ggucacccac cauagggcau gaucaacacc gcaaccuuuc     1860

cuuuuucccc cagugauucu gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa     1920

auuuaguaag cuuaaggcgg ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc     1980

ucucacuuuc aguaaauaaa auaaaagcag caacagaaau aaagaaauaa augaaauuca     2040

aaaugaaaua aauauugugu ugugcagcau uaaaaaauca auaaaaauua aaaaugagca     2100

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     2220

gagccaccag aauu                                                       2234


<210>  1516
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1516
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1517
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1517
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1518
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1518
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1519
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1519
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccaggug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1520
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1520
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1521
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1521
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccggug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1522
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1522
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaaugcua uuaccacaau acuuacugcu      120

guaaccuucu gcuuugccuc uggccaaaac auaacagaag aauuuuauca aucaacuugc      180

uccgcuguaa gcaaaggcua ccuaucagca uuacgcaccg gcugguacac aucaguaaua      240

acaauagaac uauccaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguaaaa      300

uuaauaaaac aagaacucga caaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaaguacuc cagccaccaa caacagagca agaagagaau uaccacgauu uaugaacuac      420

acacuaaaca augcaaaaaa aacaaacgua acacuaucaa aaaaacguaa acgcagauuc      480

uuaggcuucc uccuaggugu aggcucagca aucgccucag gaguggcagu uuguaaagua      540

cuacaccuag aaggagaagu aaacaaaauc aaaucugccc uuuuaucgac aaacaaagca      600

guaguaucgu uauccaaugg agucucagua uugacauuca aaguauuaga ccuaaaaaau      660

uauauagaua aacaacucuu accuaucuua aauaaacaaa gcugcucaau aaguaacaua      720

gaaaccguaa uagaauuuca acaaaaaaac aauagacucc uugagaucac ucgagaauuu      780

ucaguaaacg cagguguaac aacaccagua agcacauaca ugcuaacaaa uagugaacua      840

uuaucucuaa uuaacgauau gcccauaacc aacgaucaaa aaaaacucau gaguaacaac      900

guacaaauag uaagacaaca auccuauagc auaaugugca uuauaaaaga agaaguacua      960

gcauauguag uccaacuacc acuauacggc guaauagaca caccaugcug gaaacuacac     1020

accucacccc uaugcacaac aaauacaaaa gaaggaucaa acauaugcuu aaccaggaca     1080

gacagaggcu gguacugcga uaacgcagga ucuguuucau ucuuccccca agcagaaaca     1140

ugcaaaguac aaucaaacag aguauuuugu gauaccauga acucacucac auuaccaucc     1200

gaagucaacc ucugcaacgu agacauauuc aaccccaaau acgacugcaa aauaaugacc     1260

ucaaaaacag auguaucauc aucaguaauc acaucacuag gagcuaucgu aucuuguuau     1320

ggaaaaacaa aaugcacagc auccaacaaa aacagaggaa uuaucaaaac auucucaaau     1380

ggaugugacu auguaucaaa caaaggagua gacaccguaa gcguaggcaa uacacuauau     1440

uacguaaaua aacaagaagg aaaaucacua uacguaaaag gugaaccaau aauaaacuuc     1500

uaugaccccc uaguauuccc aucagaugaa uuugacgcaa gcauaucaca agucaacgaa     1560

aaaauaaacc aaucacuggc auucauucgc aaaucagaug aacuucucca caacguaaac     1620

gcugguaaaa gcacuacaaa cauaaugaua acaacaauca ucauugucau aauaguuauu     1680

cuauuaucac uaaucgcagu aggauuacua cuauacugua aagcgaggua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1523
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1523
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccacaau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgaaccg gcugguacac cuccgugauc      240

accaucgagc ugucaaacau caaggagaac aagugcaacg ggaccgaugc caagguuaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccacuc cggcaaccaa caaccgcgcc aggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaaugug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccuaggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

uugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

gugguaagcc ucuccaacgg cgucagcguu cugaccuuca aggugcugga ccucaagaac      660

uauaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cucaaacauc      720

gaaacgguga uugaguucca gcagaagaac aaccggcucc uggaaaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cuaucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga agaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcacaac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccucu     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagacag acgugagcuc cagcgugauc acaucccugg gggccaucgu cagcugcuac     1320

ggcaagacua aguguacugc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacguuaaua agcaggaggg caagagccuc uacgugaaag gggagcccau cauuaacuuc     1500

uacgacccac ugguuuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgugauu     1680

cugcuguccc ucaucgccgu ggggcugcug cuuuacugca aggcccggug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1524
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1524
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccaa caaccgcgcc cggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccugggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

guggugagcc ucuccaacgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      720

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1320

ggcaagacga agugcaccgc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1500

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1680

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1525
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1525
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccaa caaccgggcc cgccgggagc ugccgcgcuu caugaacuac      420

acccucaaca acgccaagaa gacgaacgug acccugagca agaagcggaa gcgccgguuc      480

cugggcuucc uccugggggu gggcuccgcg aucgccagcg gcgucgccgu gugcaaggug      540

cugcaccucg agggggaggu caacaagauc aaguccgccc ugcugagcac caacaaggcc      600

gugguguccc ucagcaacgg cgucuccgug cugaccuuca aggugcugga ccucaagaac      660

uacaucgaca agcagcugcu gcccauccuc aacaagcaga gcugcuccau cagcaacauc      720

gagacgguca ucgaguucca gcagaagaac aaccgccugc uggagaucac ccgggaguuc      780

uccgugaacg cgggggugac cacccccguc agcacguaca ugcucaccaa cagcgagcug      840

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugcgccagca guccuacagc aucaugugca ucaucaagga ggagguccug      960

gccuacgugg ugcagcuccc gcuguacggc gucaucgaca cccccugcug gaagcugcac     1020

acgagccccc ucugcaccac caacaccaag gaggggagca acaucugccu gacgcggacc     1080

gaccgcggcu gguacugcga caacgccggc uccgugagcu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg gguguucugc gacaccauga acagccugac gcucccgucc     1200

gaggugaacc ugugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acguguccag cuccgugauc accagccugg gggccaucgu cuccugcuac     1320

ggcaagacga agugcaccgc gagcaacaag aaccgcggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguca gcguggggaa cacccucuac     1440

uacgugaaca agcaggaggg caagucccug uacgucaagg gggagcccau caucaacuuc     1500

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggugaacgag     1560

aagaucaacc agucccucgc cuucauccgg aaguccgacg agcugcugca caacgucaac     1620

gccggcaagu ccacgaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcucagcc ugaucgccgu cgggcugcuc cuguacugca aggcgcgcug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1526
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1526
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccaa caaccgcgcc cgccgcgagc ucccccgcuu caugaacuac      420

acccucaaca acgccaagaa gaccaacguc acccucucca agaagcgcaa gcgccgcuuc      480

cucggcuucc uccucggcgu cggcuccgcc aucgccuccg gcgucgccgu cugcaagguc      540

cuccaccucg agggcgaggu caacaagauc aaguccgccc uccucuccac caacaaggcc      600

gucgucuccc ucuccaacgg cgucuccguc cucaccuuca agguccucga ccucaagaac      660

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      720

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      780

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      840

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      900

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      960

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac     1020

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1080

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1140

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1200

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1320

ggcaagacca agugcaccgc cuccaacaag aaccgcggca ucaucaagac cuucuccaac     1380

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1440

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1500

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1560

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1620

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1680

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1527
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1527
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccaa caauagggcu cggcgcgagu ugccucgauu uaugaacuac      420

acgcucaaua acgcaaagaa aacuaaugug acccugucga agaaacguaa gagaagguuc      480

cugggcuuuc ucuuaggggu cggaucagcc auagcuagcg gcguggccgu uuguaaggug      540

cugcaccuug aaggugaggu caacaaaauc aagagugcgu ugcuguccac aaauaaagca      600

gugguaucuc uaagcaacgg gguuuccgug cucacuuuca agguccugga ccuuaaaaau      660

uauauugaua agcaacuguu gccaauccuc aacaaacagu caugcaguau uagcaacauc      720

gaaaccguga uagaguuuca gcagaagaau aaccggcugu uagagauuac acgcgaguuc      780

ucugugaaug ccggagucac cacgccgguu uccacuuaca ugcugacaaa cucagaacuc      840

cuuagccuga ucaaugacau gcccauuacc aacgaucaaa agaaauugau gaguaauaac      900

gugcagaucg uaagacagca gucuuauucc aucaugugua uuauaaagga agaggugcua      960

gcuuacgucg ugcaacugcc ucucuacggc guuaucgaca cuccaugcug gaaacugcau     1020

acaagccccc uuuguaccac gaauaccaag gaaggcucga acauuugccu gacaaggacu     1080

gaucgggggu gguauuguga caaugccgga ucuguguccu uuuucccuca ggcagagacc     1140

ugcaaagucc agucaaaccg cguguuuugu gauacaauga auaguuugac ucucccaagc     1200

gagguaaacc ugugcaaugu ugacaucuuc aaccccaagu acgauugcaa gauaaugacc     1260

uccaaaacag acgugucuag cucagucauu accaguuuag gugcuaucgu guccuguuau     1320

ggcaagacua aaugcacggc cagcaacaag aaucgaggga ucauuaaaac auuuucuaac     1380

ggaugugauu acgucucaaa uaagggcgug gacaccguua guguggguaa cacucuguau     1440

uacguaaaua agcaagaagg gaaaagccua uaugucaagg gagagccuau cauuaacuuc     1500

uacgacccac ucguguuccc guccgaugaa uuugacgcgu cuauaucgca gguuaaugag     1560

aaaaucaacc agagccuggc cuucauuaga aaguccgaug aacuuuugca caaugugaac     1620

gcaggcaaau caaccacaaa uaucaugauc accacuauua uaaucgucau uaucgugauu     1680

cugcucaguc ugaucgcugu aggccuucug uuguacugca aggccaggug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1528
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1528
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccaa caacagagcc agaagagagc ugcccagauu caugaacuac      420

acccugaaca acgccaagaa gaccaacgug acccugagca agaagagaaa gagaagauuc      480

cugggcuucc ugcugggcgu gggcagcgcc aucgccagcg gcguggccgu gugcaaggug      540

cugcaccugg agggcgaggu gaacaagauc aagagcgccc ugcugagcac caacaaggcc      600

guggugagcc ugagcaacgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      660

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      720

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      780

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      840

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      900

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      960

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac     1020

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1080

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1140

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1200

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1320

ggcaagacca agugcaccgc cagcaacaag aacagaggca ucaucaagac cuucagcaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1440

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1500

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1560

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1620

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1680

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1529
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1529
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacaaa caaucgggcu cgcagagagc ucccucgguu uaugaacuac      420

acccugaaua acgccaagaa aacaaauguc acccuuucua agaaacgcaa gagacgguuc      480

cugggguuuc uccugggagu gggcagcgcg auugccuccg ggguugcugu guguaagguc      540

cuucaccugg aaggagaggu gaacaaaauc aagagcgccc uccugucuac gaauaaagcu      600

guuguguccc ugagcaacgg cgucucugug cucacauuca aggugcugga ccuuaaaaau      660

uauauugaua agcaacugcu cccgauccug aacaaacagu ccugcagcau uucuaacauc      720

gaaaccguca uugaguuuca gcagaagaau aaccgccuuc uggagaucac aagagaauuu      780

uccguuaaug ccggcgugac cacccccgug agcacauaca ugcucacgaa cuccgagcug      840

cugucucuca ucaaugacau gccuauuacc aacgaucaaa agaaacugau gagcaauaac      900

guccagaucg ugcggcagca guccuauagc auuaugugua ucauuaagga agagguucuu      960

gcguacgugg uccaacugcc ccucuacggg gugaucgaca caccuugcug gaaacugcau     1020

accucucccc uuuguacaac caauacgaag gaaggaucca acaucugccu gacacgcacc     1080

gauagaggcu gguauuguga caaugccggg agcguuucuu ucuucccuca ggcugagacc     1140

ugcaaagugc agagcaaccg ggucuuuugu gauacaauga acucccucac ccugccgucu     1200

gaggugaauc ugugcaaugu cgacauuuuc aaccccaagu acgauugcaa gaucaugaca     1260

agcaaaacgg acguguccag cucuguuauu accucccucg gagccaucgu gagcuguuau     1320

ggcaagacaa aaugcaccgc uucuaacaag aaucgcggga uuaucaaaac auuuuccaac     1380

ggaugugauu acgucagcaa uaagggcgug gacaccguuu ccgugggcaa cacgcuguau     1440

uacgucaaua agcaagaagg gaaaucucuu uaugugaagg gagagccuau cauuaacuuc     1500

uacgaccccc ugguguuccc uagcgaugaa uuugacgccu ccaucucuca gguuaaugag     1560

aaaauuaacc agagccucgc cuucaucaga aaguccgaug aacugcugca caaugucaac     1620

gcuggcaaaa gcaccacaaa uauuaugauc accacaauua ucaucgugau uaucgugauu     1680

cuucucucuc ugaucgcggu cgggcugcuc cuguacugca aggcccggug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1530
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1530
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaaugcua uuaccacaau acuuacugcu      120

guaaccuucu gcuuugccuc uggccaaaac auaacagaag aauuuuauca aucaacuugc      180

uccgcuguaa gcaaaggcua ccuaucagca uuacgcaccg gcugguacac aucaguaaua      240

acaauagaac uauccaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguaaaa      300

uuaauaaaac aagaacucga caaauacaaa aacgcaguaa cagaauuaca acuacuaaug      360

caaaguacuc cagccaccaa caacagagca agaagagaau uaccacgauu uaugaacuac      420

acacuaaaca augcaaaaaa aacaaacgua acacuaucaa aaaaacguaa acgcagauuc      480

uuaggcuucc uccuaggugu aggcucagca aucgccucag gaguggcagu uuguaaagua      540

cuacaccuag aaggagaagu aaacaaaauc aaaucugccc uuuuaucgac aaacaaagca      600

guaguaucgu uauccaaugg agucucagua uugacauuca aaguauuaga ccuaaaaaau      660

uauauagaua aacaacucuu accuaucuua aauaaacaaa gcugcucaau aaguaacaua      720

gaaaccguaa uagaauuuca acaaaaaaac aauagacucc uugagaucac ucgagaauuu      780

ucaguaaacg cagguguaac aacaccagua agcacauaca ugcuaacaaa uagugaacua      840

uuaucucuaa uuaacgauau gcccauaacc aacgaucaaa aaaaacucau gaguaacaac      900

guacaaauag uaagacaaca auccuauagc auaaugugca uuauaaaaga agaaguacua      960

gcauauguag uccaacuacc acuauacggc guaauagaca caccaugcug gaaacuacac     1020

accucacccc uaugcacaac aaauacaaaa gaaggaucaa acauaugcuu aaccaggaca     1080

gacagaggcu gguacugcga uaacgcagga ucuguuucau ucuuccccca agcagaaaca     1140

ugcaaaguac aaucaaacag aguauuuugu gauaccauga acucacucac auuaccaucc     1200

gaagucaacc ucugcaacgu agacauauuc aaccccaaau acgacugcaa aauaaugacc     1260

ucaaaaacag auguaucauc aucaguaauc acaucacuag gagcuaucgu aucuuguuau     1320

ggaaaaacaa aaugcacagc auccaacaaa aacagaggaa uuaucaaaac auucucaaau     1380

ggaugugacu auguaucaaa caaaggagua gacaccguaa gcguaggcaa uacacuauau     1440

uacguaaaua aacaagaagg aaaaucacua uacguaaaag gugaaccaau aauaaacuuc     1500

uaugaccccc uaguauuccc aucagaugaa uuugacgcaa gcauaucaca agucaacgaa     1560

aaaauaaacc aaucacuggc auucauucgc aaaucagaug aacuucucca caacguaaac     1620

gcugguaaaa gcacuacaaa cauaaugaua acaacaauca ucauugucau aauaguuauu     1680

cuauuaucac uaaucgcagu aggauuacua cuauacugua aagcgaggua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1531
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1531
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccacaau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgaaccg gcugguacac cuccgugauc      240

accaucgagc ugucaaacau caaggagaac aagugcaacg ggaccgaugc caagguuaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccacuc cggcaaccaa caaccgcgcc aggcgcgagc ugccccgguu caugaacuac      420

acccucaaca acgccaagaa gacgaaugug acccugagca agaagcgcaa gcggcgcuuc      480

cugggcuucc uccuaggggu gggcuccgcc aucgcgagcg gcgucgccgu gugcaaggug      540

uugcaccucg agggggaggu caacaagauc aagagcgccc ugcuguccac caacaaggcc      600

gugguaagcc ucuccaacgg cgucagcguu cugaccuuca aggugcugga ccucaagaac      660

uauaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cucaaacauc      720

gaaacgguga uugaguucca gcagaagaac aaccggcucc uggaaaucac ccgcgaguuc      780

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      840

cuaucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      900

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga agaggugcug      960

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac     1020

acgagccccc ugugcacaac caacaccaag gaggggucca acaucugccu cacgcgcacc     1080

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1140

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccucu     1200

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1260

uccaagacag acgugagcuc cagcgugauc acaucccugg gggccaucgu cagcugcuac     1320

ggcaagacua aguguacugc cagcaacaag aaccggggga ucaucaagac cuucuccaac     1380

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1440

uacguuaaua agcaggaggg caagagccuc uacgugaaag gggagcccau cauuaacuuc     1500

uacgacccac ugguuuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1560

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1620

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgugau caucgugauu     1680

cugcuguccc ucaucgccgu ggggcugcug cuuuacugca aggcccggug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1532
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1532
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1533
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1533
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1534
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1534
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1535
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1535
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1536
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1536
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1537
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1537
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1538
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1538
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aaugcuauua ccacaauacu uacugcugua accuucugcu uugccucugg ccaaaacaua      180

acagaagaau uuuaucaauc aacuugcucc gcuguaagca aaggcuaccu aucagcauua      240

cgcaccggcu gguacacauc aguaauaaca auagaacuau ccaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguaaaauua auaaaacaag aacucgacaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa aguacuccag ccaccaacaa cagagcaaga      420

agagaauuac cacgauuuau gaacuacaca cuaaacaaug caaaaaaaac aaacguaaca      480

cuaucaaaaa aacguaaacg cagauucuua ggcuuccucc uagguguagg cucagcaauc      540

gccucaggag uggcaguuug uaaaguacua caccuagaag gagaaguaaa caaaaucaaa      600

ucugcccuuu uaucgacaaa caaagcagua guaucguuau ccaauggagu cucaguauug      660

acauucaaag uauuagaccu aaaaaauuau auagauaaac aacucuuacc uaucuuaaau      720

aaacaaagcu gcucaauaag uaacauagaa accguaauag aauuucaaca aaaaaacaau      780

agacuccuug agaucacucg agaauuuuca guaaacgcag guguaacaac accaguaagc      840

acauacaugc uaacaaauag ugaacuauua ucucuaauua acgauaugcc cauaaccaac      900

gaucaaaaaa aacucaugag uaacaacgua caaauaguaa gacaacaauc cuauagcaua      960

augugcauua uaaaagaaga aguacuagca uauguagucc aacuaccacu auacggcgua     1020

auagacacac caugcuggaa acuacacacc ucaccccuau gcacaacaaa uacaaaagaa     1080

ggaucaaaca uaugcuuaac caggacagac agaggcuggu acugcgauaa cgcaggaucu     1140

guuucauucu ucccccaagc agaaacaugc aaaguacaau caaacagagu auuuugugau     1200

accaugaacu cacucacauu accauccgaa gucaaccucu gcaacguaga cauauucaac     1260

cccaaauacg acugcaaaau aaugaccuca aaaacagaug uaucaucauc aguaaucaca     1320

ucacuaggag cuaucguauc uuguuaugga aaaacaaaau gcacagcauc caacaaaaac     1380

agaggaauua ucaaaacauu cucaaaugga ugugacuaug uaucaaacaa aggaguagac     1440

accguaagcg uaggcaauac acuauauuac guaaauaaac aagaaggaaa aucacuauac     1500

guaaaaggug aaccaauaau aaacuucuau gacccccuag uauucccauc agaugaauuu     1560

gacgcaagca uaucacaagu caacgaaaaa auaaaccaau cacuggcauu cauucgcaaa     1620

ucagaugaac uucuccacaa cguaaacgcu gguaaaagca cuacaaacau aaugauaaca     1680

acaaucauca uugucauaau aguuauucua uuaucacuaa ucgcaguagg auuacuacua     1740

uacuguaaag cgagguaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1539
<211>  2021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1539
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccacaauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgaaccggcu gguacaccuc cgugaucacc aucgagcugu caaacaucaa ggagaacaag      300

ugcaacggga ccgaugccaa gguuaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacuccgg caaccaacaa ccgcgccagg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaaugugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uagggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caagguguug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug guaagccucu ccaacggcgu cagcguucug      660

accuucaagg ugcuggaccu caagaacuau aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucuc aaacaucgaa acggugauug aguuccagca gaagaacaac      780

cggcuccugg aaaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccua ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggaaga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcacaaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccucugag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagacagacg ugagcuccag cgugaucaca     1320

ucccuggggg ccaucgucag cugcuacggc aagacuaagu guacugccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac guuaauaagc aggagggcaa gagccucuac     1500

gugaaagggg agcccaucau uaacuucuac gacccacugg uuuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauucug cugucccuca ucgccguggg gcugcugcuu     1740

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1800

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1860

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1980

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         2021


<210>  1540
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1540
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccaacaa ccgcgcccgg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uggggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug gugagccucu ccaacggcgu cagcgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      780

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1320

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1500

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1740

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1541
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1541
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccaacaa ccgggcccgc      420

cgggagcugc cgcgcuucau gaacuacacc cucaacaacg ccaagaagac gaacgugacc      480

cugagcaaga agcggaagcg ccgguuccug ggcuuccucc uggggguggg cuccgcgauc      540

gccagcggcg ucgccgugug caaggugcug caccucgagg gggaggucaa caagaucaag      600

uccgcccugc ugagcaccaa caaggccgug gugucccuca gcaacggcgu cuccgugcug      660

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccucaac      720

aagcagagcu gcuccaucag caacaucgag acggucaucg aguuccagca gaagaacaac      780

cgccugcugg agaucacccg ggaguucucc gugaacgcgg gggugaccac ccccgucagc      840

acguacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucgugc gccagcaguc cuacagcauc      960

augugcauca ucaaggagga gguccuggcc uacguggugc agcucccgcu guacggcguc     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccucu gcaccaccaa caccaaggag     1080

gggagcaaca ucugccugac gcggaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgggu guucugcgac     1200

accaugaaca gccugacgcu cccguccgag gugaaccugu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgugaucacc     1320

agccuggggg ccaucgucuc cugcuacggc aagacgaagu gcaccgcgag caacaagaac     1380

cgcgggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgucagcg uggggaacac ccucuacuac gugaacaagc aggagggcaa gucccuguac     1500

gucaaggggg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1560

gacgccucca ucagccaggu gaacgagaag aucaaccagu cccucgccuu cauccggaag     1620

uccgacgagc ugcugcacaa cgucaacgcc ggcaagucca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cucagccuga ucgccgucgg gcugcuccug     1740

uacugcaagg cgcgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1542
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1542
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccaacaa ccgcgcccgc      420

cgcgagcucc cccgcuucau gaacuacacc cucaacaacg ccaagaagac caacgucacc      480

cucuccaaga agcgcaagcg ccgcuuccuc ggcuuccucc ucggcgucgg cuccgccauc      540

gccuccggcg ucgccgucug caagguccuc caccucgagg gcgaggucaa caagaucaag      600

uccgcccucc ucuccaccaa caaggccguc gucucccucu ccaacggcgu cuccguccuc      660

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      720

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      780

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      840

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      900

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      960

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc     1020

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag     1080

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1140

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1200

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1320

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagaac     1380

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1440

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1500

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1560

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1620

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1680

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1740

uacugcaagg cccgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1543
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1543
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccaacaa uagggcucgg      420

cgcgaguugc cucgauuuau gaacuacacg cucaauaacg caaagaaaac uaaugugacc      480

cugucgaaga aacguaagag aagguuccug ggcuuucucu uaggggucgg aucagccaua      540

gcuagcggcg uggccguuug uaaggugcug caccuugaag gugaggucaa caaaaucaag      600

agugcguugc uguccacaaa uaaagcagug guaucucuaa gcaacggggu uuccgugcuc      660

acuuucaagg uccuggaccu uaaaaauuau auugauaagc aacuguugcc aauccucaac      720

aaacagucau gcaguauuag caacaucgaa accgugauag aguuucagca gaagaauaac      780

cggcuguuag agauuacacg cgaguucucu gugaaugccg gagucaccac gccgguuucc      840

acuuacaugc ugacaaacuc agaacuccuu agccugauca augacaugcc cauuaccaac      900

gaucaaaaga aauugaugag uaauaacgug cagaucguaa gacagcaguc uuauuccauc      960

auguguauua uaaaggaaga ggugcuagcu uacgucgugc aacugccucu cuacggcguu     1020

aucgacacuc caugcuggaa acugcauaca agcccccuuu guaccacgaa uaccaaggaa     1080

ggcucgaaca uuugccugac aaggacugau cggggguggu auugugacaa ugccggaucu     1140

guguccuuuu ucccucaggc agagaccugc aaaguccagu caaaccgcgu guuuugugau     1200

acaaugaaua guuugacucu cccaagcgag guaaaccugu gcaauguuga caucuucaac     1260

cccaaguacg auugcaagau aaugaccucc aaaacagacg ugucuagcuc agucauuacc     1320

aguuuaggug cuaucguguc cuguuauggc aagacuaaau gcacggccag caacaagaau     1380

cgagggauca uuaaaacauu uucuaacgga ugugauuacg ucucaaauaa gggcguggac     1440

accguuagug uggguaacac ucuguauuac guaaauaagc aagaagggaa aagccuauau     1500

gucaagggag agccuaucau uaacuucuac gacccacucg uguucccguc cgaugaauuu     1560

gacgcgucua uaucgcaggu uaaugagaaa aucaaccaga gccuggccuu cauuagaaag     1620

uccgaugaac uuuugcacaa ugugaacgca ggcaaaucaa ccacaaauau caugaucacc     1680

acuauuauaa ucgucauuau cgugauucug cucagucuga ucgcuguagg ccuucuguug     1740

uacugcaagg ccaggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1544
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1544
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccaacaa cagagccaga      420

agagagcugc ccagauucau gaacuacacc cugaacaacg ccaagaagac caacgugacc      480

cugagcaaga agagaaagag aagauuccug ggcuuccugc ugggcguggg cagcgccauc      540

gccagcggcg uggccgugug caaggugcug caccuggagg gcgaggugaa caagaucaag      600

agcgcccugc ugagcaccaa caaggccgug gugagccuga gcaacggcgu gagcgugcug      660

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      780

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      840

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      900

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      960

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag     1080

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1140

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1200

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1260

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1320

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagaac     1380

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1500

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1560

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1620

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1740

uacugcaagg ccagaugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1545
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1545
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaaacaa ucgggcucgc      420

agagagcucc cucgguuuau gaacuacacc cugaauaacg ccaagaaaac aaaugucacc      480

cuuucuaaga aacgcaagag acgguuccug ggguuucucc ugggaguggg cagcgcgauu      540

gccuccgggg uugcugugug uaagguccuu caccuggaag gagaggugaa caaaaucaag      600

agcgcccucc ugucuacgaa uaaagcuguu gugucccuga gcaacggcgu cucugugcuc      660

acauucaagg ugcuggaccu uaaaaauuau auugauaagc aacugcuccc gauccugaac      720

aaacaguccu gcagcauuuc uaacaucgaa accgucauug aguuucagca gaagaauaac      780

cgccuucugg agaucacaag agaauuuucc guuaaugccg gcgugaccac ccccgugagc      840

acauacaugc ucacgaacuc cgagcugcug ucucucauca augacaugcc uauuaccaac      900

gaucaaaaga aacugaugag caauaacguc cagaucgugc ggcagcaguc cuauagcauu      960

auguguauca uuaaggaaga gguucuugcg uacguggucc aacugccccu cuacggggug     1020

aucgacacac cuugcuggaa acugcauacc ucuccccuuu guacaaccaa uacgaaggaa     1080

ggauccaaca ucugccugac acgcaccgau agaggcuggu auugugacaa ugccgggagc     1140

guuucuuucu ucccucaggc ugagaccugc aaagugcaga gcaaccgggu cuuuugugau     1200

acaaugaacu cccucacccu gccgucugag gugaaucugu gcaaugucga cauuuucaac     1260

cccaaguacg auugcaagau caugacaagc aaaacggacg uguccagcuc uguuauuacc     1320

ucccucggag ccaucgugag cuguuauggc aagacaaaau gcaccgcuuc uaacaagaau     1380

cgcgggauua ucaaaacauu uuccaacgga ugugauuacg ucagcaauaa gggcguggac     1440

accguuuccg ugggcaacac gcuguauuac gucaauaagc aagaagggaa aucucuuuau     1500

gugaagggag agccuaucau uaacuucuac gacccccugg uguucccuag cgaugaauuu     1560

gacgccucca ucucucaggu uaaugagaaa auuaaccaga gccucgccuu caucagaaag     1620

uccgaugaac ugcugcacaa ugucaacgcu ggcaaaagca ccacaaauau uaugaucacc     1680

acaauuauca ucgugauuau cgugauucuu cucucucuga ucgcggucgg gcugcuccug     1740

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1546
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1546
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aaugcuauua ccacaauacu uacugcugua accuucugcu uugccucugg ccaaaacaua      180

acagaagaau uuuaucaauc aacuugcucc gcuguaagca aaggcuaccu aucagcauua      240

cgcaccggcu gguacacauc aguaauaaca auagaacuau ccaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguaaaauua auaaaacaag aacucgacaa auacaaaaac      360

gcaguaacag aauuacaacu acuaaugcaa aguacuccag ccaccaacaa cagagcaaga      420

agagaauuac cacgauuuau gaacuacaca cuaaacaaug caaaaaaaac aaacguaaca      480

cuaucaaaaa aacguaaacg cagauucuua ggcuuccucc uagguguagg cucagcaauc      540

gccucaggag uggcaguuug uaaaguacua caccuagaag gagaaguaaa caaaaucaaa      600

ucugcccuuu uaucgacaaa caaagcagua guaucguuau ccaauggagu cucaguauug      660

acauucaaag uauuagaccu aaaaaauuau auagauaaac aacucuuacc uaucuuaaau      720

aaacaaagcu gcucaauaag uaacauagaa accguaauag aauuucaaca aaaaaacaau      780

agacuccuug agaucacucg agaauuuuca guaaacgcag guguaacaac accaguaagc      840

acauacaugc uaacaaauag ugaacuauua ucucuaauua acgauaugcc cauaaccaac      900

gaucaaaaaa aacucaugag uaacaacgua caaauaguaa gacaacaauc cuauagcaua      960

augugcauua uaaaagaaga aguacuagca uauguagucc aacuaccacu auacggcgua     1020

auagacacac caugcuggaa acuacacacc ucaccccuau gcacaacaaa uacaaaagaa     1080

ggaucaaaca uaugcuuaac caggacagac agaggcuggu acugcgauaa cgcaggaucu     1140

guuucauucu ucccccaagc agaaacaugc aaaguacaau caaacagagu auuuugugau     1200

accaugaacu cacucacauu accauccgaa gucaaccucu gcaacguaga cauauucaac     1260

cccaaauacg acugcaaaau aaugaccuca aaaacagaug uaucaucauc aguaaucaca     1320

ucacuaggag cuaucguauc uuguuaugga aaaacaaaau gcacagcauc caacaaaaac     1380

agaggaauua ucaaaacauu cucaaaugga ugugacuaug uaucaaacaa aggaguagac     1440

accguaagcg uaggcaauac acuauauuac guaaauaaac aagaaggaaa aucacuauac     1500

guaaaaggug aaccaauaau aaacuucuau gacccccuag uauucccauc agaugaauuu     1560

gacgcaagca uaucacaagu caacgaaaaa auaaaccaau cacuggcauu cauucgcaaa     1620

ucagaugaac uucuccacaa cguaaacgcu gguaaaagca cuacaaacau aaugauaaca     1680

acaaucauca uugucauaau aguuauucua uuaucacuaa ucgcaguagg auuacuacua     1740

uacuguaaag cgagguaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1547
<211>  2253
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1547
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccacaauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgaaccggcu gguacaccuc cgugaucacc aucgagcugu caaacaucaa ggagaacaag      300

ugcaacggga ccgaugccaa gguuaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacuccgg caaccaacaa ccgcgccagg      420

cgcgagcugc cccgguucau gaacuacacc cucaacaacg ccaagaagac gaaugugacc      480

cugagcaaga agcgcaagcg gcgcuuccug ggcuuccucc uagggguggg cuccgccauc      540

gcgagcggcg ucgccgugug caagguguug caccucgagg gggaggucaa caagaucaag      600

agcgcccugc uguccaccaa caaggccgug guaagccucu ccaacggcgu cagcguucug      660

accuucaagg ugcuggaccu caagaacuau aucgacaagc agcugcugcc cauccugaac      720

aagcagagcu gcuccaucuc aaacaucgaa acggugauug aguuccagca gaagaacaac      780

cggcuccugg aaaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      840

acguacaugc ugaccaacag cgagcuccua ucccugauca acgacaugcc gaucaccaac      900

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      960

augugcauca ucaaggaaga ggugcuggcg uacguggucc agcugccccu cuacggcgug     1020

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcacaaccaa caccaaggag     1080

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1140

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1200

accaugaacu cccugacgcu gcccucugag guaaaccucu gcaacgucga caucuucaac     1260

cccaaguacg acugcaagau caugaccucc aagacagacg ugagcuccag cgugaucaca     1320

ucccuggggg ccaucgucag cugcuacggc aagacuaagu guacugccag caacaagaac     1380

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1440

accguguccg ucgggaacac ccuguacuac guuaauaagc aggagggcaa gagccucuac     1500

gugaaagggg agcccaucau uaacuucuac gacccacugg uuuuccccuc cgacgaguuc     1560

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1620

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1680

accaucauca ucgugaucau cgugauucug cugucccuca ucgccguggg gcugcugcuu     1740

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1800

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1860

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1920

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1980

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     2040

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2100

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2220

cccccaaagg cucuuuucag agccaccaga auu                                  2253


<210>  1548
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1548
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccugg gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      660

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1549
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1549
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc      480

aacaacgcca agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc      540

uuccuccugg gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac      600

cucgaggggg aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug      660

ucccucagca acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg      780

gucaucgagu uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug      840

aacgcggggg ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugcgcc agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac     1020

guggugcagc ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccucugca ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug     1260

aaccugugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag     1380

acgaagugca ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug     1500

aacaagcagg agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc     1620

aaccaguccc ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc     1680

aaguccacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc     1740

agccugaucg ccgucgggcu gcuccuguac ugcaaggcgc gcugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1550
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1550
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc      480

aacaacgcca agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc      540

uuccuccucg gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      600

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      660

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1551
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1551
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc      480

aauaacgcaa agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc      540

uuucucuuag gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac      600

cuugaaggug aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua      660

ucucuaagca acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu      720

gauaagcaac uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc      780

gugauagagu uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug      840

aaugccggag ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc      900

cugaucaaug acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag      960

aucguaagac agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac     1020

gucgugcaac ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc     1080

ccccuuugua ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg     1140

gggugguauu gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa     1200

guccagucaa accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua     1260

aaccugugca auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa     1320

acagacgugu cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag     1380

acuaaaugca cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu     1440

gauuacgucu caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua     1500

aauaagcaag aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac     1560

ccacucgugu ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc     1620

aaccagagcc uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc     1680

aaaucaacca caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc     1740

agucugaucg cuguaggccu ucuguuguac ugcaaggcca ggugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1552
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1552
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug      480

aacaacgcca agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc      540

uuccugcugg gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      600

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      660

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1553
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1553
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug      480

aauaacgcca agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg      540

uuucuccugg gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac      600

cuggaaggag aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug      660

ucccugagca acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu      720

gauaagcaac ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc      780

gucauugagu uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu      840

aaugccggcg ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu      900

cucaucaaug acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag      960

aucgugcggc agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac     1020

gugguccaac ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu     1080

ccccuuugua caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga     1140

ggcugguauu gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa     1200

gugcagagca accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug     1260

aaucugugca augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa     1320

acggacgugu ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag     1380

acaaaaugca ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu     1440

gauuacguca gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc     1500

aauaagcaag aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac     1560

ccccuggugu ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu     1620

aaccagagcc ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc     1680

aaaagcacca caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc     1740

ucucugaucg cggucgggcu gcuccuguac ugcaaggccc ggugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1554
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1554
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaau gcuauuacca caauacuuac ugcuguaacc      180

uucugcuuug ccucuggcca aaacauaaca gaagaauuuu aucaaucaac uugcuccgcu      240

guaagcaaag gcuaccuauc agcauuacgc accggcuggu acacaucagu aauaacaaua      300

gaacuaucca acauaaaaga aaauaaaugc aacggaacag acgcaaaagu aaaauuaaua      360

aaacaagaac ucgacaaaua caaaaacgca guaacagaau uacaacuacu aaugcaaagu      420

acuccagcca ccaacaacag agcaagaaga gaauuaccac gauuuaugaa cuacacacua      480

aacaaugcaa aaaaaacaaa cguaacacua ucaaaaaaac guaaacgcag auucuuaggc      540

uuccuccuag guguaggcuc agcaaucgcc ucaggagugg caguuuguaa aguacuacac      600

cuagaaggag aaguaaacaa aaucaaaucu gcccuuuuau cgacaaacaa agcaguagua      660

ucguuaucca auggagucuc aguauugaca uucaaaguau uagaccuaaa aaauuauaua      720

gauaaacaac ucuuaccuau cuuaaauaaa caaagcugcu caauaaguaa cauagaaacc      780

guaauagaau uucaacaaaa aaacaauaga cuccuugaga ucacucgaga auuuucagua      840

aacgcaggug uaacaacacc aguaagcaca uacaugcuaa caaauaguga acuauuaucu      900

cuaauuaacg auaugcccau aaccaacgau caaaaaaaac ucaugaguaa caacguacaa      960

auaguaagac aacaauccua uagcauaaug ugcauuauaa aagaagaagu acuagcauau     1020

guaguccaac uaccacuaua cggcguaaua gacacaccau gcuggaaacu acacaccuca     1080

ccccuaugca caacaaauac aaaagaagga ucaaacauau gcuuaaccag gacagacaga     1140

ggcugguacu gcgauaacgc aggaucuguu ucauucuucc cccaagcaga aacaugcaaa     1200

guacaaucaa acagaguauu uugugauacc augaacucac ucacauuacc auccgaaguc     1260

aaccucugca acguagacau auucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1320

acagauguau caucaucagu aaucacauca cuaggagcua ucguaucuug uuauggaaaa     1380

acaaaaugca cagcauccaa caaaaacaga ggaauuauca aaacauucuc aaauggaugu     1440

gacuauguau caaacaaagg aguagacacc guaagcguag gcaauacacu auauuacgua     1500

aauaaacaag aaggaaaauc acuauacgua aaaggugaac caauaauaaa cuucuaugac     1560

ccccuaguau ucccaucaga ugaauuugac gcaagcauau cacaagucaa cgaaaaaaua     1620

aaccaaucac uggcauucau ucgcaaauca gaugaacuuc uccacaacgu aaacgcuggu     1680

aaaagcacua caaacauaau gauaacaaca aucaucauug ucauaauagu uauucuauua     1740

ucacuaaucg caguaggauu acuacuauac uguaaagcga gguaaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1555
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1555
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca caauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcga accggcuggu acaccuccgu gaucaccauc      300

gagcugucaa acaucaagga gaacaagugc aacgggaccg augccaaggu uaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acuccggcaa ccaacaaccg cgccaggcgc gagcugcccc gguucaugaa cuacacccuc      480

aacaacgcca agaagacgaa ugugacccug agcaagaagc gcaagcggcg cuuccugggc      540

uuccuccuag gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa gguguugcac      600

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggua      660

agccucucca acggcgucag cguucugacc uucaaggugc uggaccucaa gaacuauauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucucaaa caucgaaacg      780

gugauugagu uccagcagaa gaacaaccgg cuccuggaaa ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccuaucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaagaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca caaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cucugaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

acagacguga gcuccagcgu gaucacaucc cugggggcca ucgucagcug cuacggcaag     1380

acuaagugua cugccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacguu     1500

aauaagcagg agggcaagag ccucuacgug aaaggggagc ccaucauuaa cuucuacgac     1560

ccacugguuu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauucugcug     1740

ucccucaucg ccguggggcu gcugcuuuac ugcaaggccc ggugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1556
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1556
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1557
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1557
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1558
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1558
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1559
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1559
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccaggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1560
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1560
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1561
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1561
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1562
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1562
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaaugcua uuaccacaau acuuacugcu guaaccuucu gcuuugccuc uggccaaaac      180

auaacagaag aauuuuauca aucaacuugc uccgcuguaa gcaaaggcua ccuaucagca      240

uuacgcaccg gcugguacac aucaguaaua acaauagaac uauccaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguaaaa uuaauaaaac aagaacucga caaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaaguacuc cagccaccaa caacagagca      420

agaagagaau uaccacgauu uaugaacuac acacuaaaca augcaaaaaa aacaaacgua      480

acacuaucaa aaaaacguaa acgcagauuc uuaggcuucc uccuaggugu aggcucagca      540

aucgccucag gaguggcagu uuguaaagua cuacaccuag aaggagaagu aaacaaaauc      600

aaaucugccc uuuuaucgac aaacaaagca guaguaucgu uauccaaugg agucucagua      660

uugacauuca aaguauuaga ccuaaaaaau uauauagaua aacaacucuu accuaucuua      720

aauaaacaaa gcugcucaau aaguaacaua gaaaccguaa uagaauuuca acaaaaaaac      780

aauagacucc uugagaucac ucgagaauuu ucaguaaacg cagguguaac aacaccagua      840

agcacauaca ugcuaacaaa uagugaacua uuaucucuaa uuaacgauau gcccauaacc      900

aacgaucaaa aaaaacucau gaguaacaac guacaaauag uaagacaaca auccuauagc      960

auaaugugca uuauaaaaga agaaguacua gcauauguag uccaacuacc acuauacggc     1020

guaauagaca caccaugcug gaaacuacac accucacccc uaugcacaac aaauacaaaa     1080

gaaggaucaa acauaugcuu aaccaggaca gacagaggcu gguacugcga uaacgcagga     1140

ucuguuucau ucuuccccca agcagaaaca ugcaaaguac aaucaaacag aguauuuugu     1200

gauaccauga acucacucac auuaccaucc gaagucaacc ucugcaacgu agacauauuc     1260

aaccccaaau acgacugcaa aauaaugacc ucaaaaacag auguaucauc aucaguaauc     1320

acaucacuag gagcuaucgu aucuuguuau ggaaaaacaa aaugcacagc auccaacaaa     1380

aacagaggaa uuaucaaaac auucucaaau ggaugugacu auguaucaaa caaaggagua     1440

gacaccguaa gcguaggcaa uacacuauau uacguaaaua aacaagaagg aaaaucacua     1500

uacguaaaag gugaaccaau aauaaacuuc uaugaccccc uaguauuccc aucagaugaa     1560

uuugacgcaa gcauaucaca agucaacgaa aaaauaaacc aaucacuggc auucauucgc     1620

aaaucagaug aacuucucca caacguaaac gcugguaaaa gcacuacaaa cauaaugaua     1680

acaacaauca ucauugucau aauaguuauu cuauuaucac uaaucgcagu aggauuacua     1740

cuauacugua aagcgaggua aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1563
<211>  2024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1563
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccacaau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgaaccg gcugguacac cuccgugauc accaucgagc ugucaaacau caaggagaac      300

aagugcaacg ggaccgaugc caagguuaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccacuc cggcaaccaa caaccgcgcc      420

aggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaaugug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccuaggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug uugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc gugguaagcc ucuccaacgg cgucagcguu      660

cugaccuuca aggugcugga ccucaagaac uauaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cucaaacauc gaaacgguga uugaguucca gcagaagaac      780

aaccggcucc uggaaaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cuaucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga agaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcacaac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccucu gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagacag acgugagcuc cagcgugauc     1320

acaucccugg gggccaucgu cagcugcuac ggcaagacua aguguacugc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacguuaaua agcaggaggg caagagccuc     1500

uacgugaaag gggagcccau cauuaacuuc uacgacccac ugguuuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauu cugcuguccc ucaucgccgu ggggcugcug     1740

cuuuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1800

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1860

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1980

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      2024


<210>  1564
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1564
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1565
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1565
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1566
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1566
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1567
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1567
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccaggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1568
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1568
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1569
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1569
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1570
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1570
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaaugcua uuaccacaau acuuacugcu guaaccuucu gcuuugccuc uggccaaaac      180

auaacagaag aauuuuauca aucaacuugc uccgcuguaa gcaaaggcua ccuaucagca      240

uuacgcaccg gcugguacac aucaguaaua acaauagaac uauccaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguaaaa uuaauaaaac aagaacucga caaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaaguacuc cagccaccaa caacagagca      420

agaagagaau uaccacgauu uaugaacuac acacuaaaca augcaaaaaa aacaaacgua      480

acacuaucaa aaaaacguaa acgcagauuc uuaggcuucc uccuaggugu aggcucagca      540

aucgccucag gaguggcagu uuguaaagua cuacaccuag aaggagaagu aaacaaaauc      600

aaaucugccc uuuuaucgac aaacaaagca guaguaucgu uauccaaugg agucucagua      660

uugacauuca aaguauuaga ccuaaaaaau uauauagaua aacaacucuu accuaucuua      720

aauaaacaaa gcugcucaau aaguaacaua gaaaccguaa uagaauuuca acaaaaaaac      780

aauagacucc uugagaucac ucgagaauuu ucaguaaacg cagguguaac aacaccagua      840

agcacauaca ugcuaacaaa uagugaacua uuaucucuaa uuaacgauau gcccauaacc      900

aacgaucaaa aaaaacucau gaguaacaac guacaaauag uaagacaaca auccuauagc      960

auaaugugca uuauaaaaga agaaguacua gcauauguag uccaacuacc acuauacggc     1020

guaauagaca caccaugcug gaaacuacac accucacccc uaugcacaac aaauacaaaa     1080

gaaggaucaa acauaugcuu aaccaggaca gacagaggcu gguacugcga uaacgcagga     1140

ucuguuucau ucuuccccca agcagaaaca ugcaaaguac aaucaaacag aguauuuugu     1200

gauaccauga acucacucac auuaccaucc gaagucaacc ucugcaacgu agacauauuc     1260

aaccccaaau acgacugcaa aauaaugacc ucaaaaacag auguaucauc aucaguaauc     1320

acaucacuag gagcuaucgu aucuuguuau ggaaaaacaa aaugcacagc auccaacaaa     1380

aacagaggaa uuaucaaaac auucucaaau ggaugugacu auguaucaaa caaaggagua     1440

gacaccguaa gcguaggcaa uacacuauau uacguaaaua aacaagaagg aaaaucacua     1500

uacguaaaag gugaaccaau aauaaacuuc uaugaccccc uaguauuccc aucagaugaa     1560

uuugacgcaa gcauaucaca agucaacgaa aaaauaaacc aaucacuggc auucauucgc     1620

aaaucagaug aacuucucca caacguaaac gcugguaaaa gcacuacaaa cauaaugaua     1680

acaacaauca ucauugucau aauaguuauu cuauuaucac uaaucgcagu aggauuacua     1740

cuauacugua aagcgaggua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1571
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1571
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccacaau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgaaccg gcugguacac cuccgugauc accaucgagc ugucaaacau caaggagaac      300

aagugcaacg ggaccgaugc caagguuaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccacuc cggcaaccaa caaccgcgcc      420

aggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaaugug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccuaggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug uugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc gugguaagcc ucuccaacgg cgucagcguu      660

cugaccuuca aggugcugga ccucaagaac uauaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cucaaacauc gaaacgguga uugaguucca gcagaagaac      780

aaccggcucc uggaaaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cuaucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga agaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcacaac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccucu gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagacag acgugagcuc cagcgugauc     1320

acaucccugg gggccaucgu cagcugcuac ggcaagacua aguguacugc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacguuaaua agcaggaggg caagagccuc     1500

uacgugaaag gggagcccau cauuaacuuc uacgacccac ugguuuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauu cugcuguccc ucaucgccgu ggggcugcug     1740

cuuuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1800

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1860

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1980

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2040


<210>  1572
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1572
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1573
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1573
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1574
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1574
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1575
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1575
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccaggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1576
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1576
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1577
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1577
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1578
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1578
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaaugcua uuaccacaau acuuacugcu guaaccuucu gcuuugccuc uggccaaaac      180

auaacagaag aauuuuauca aucaacuugc uccgcuguaa gcaaaggcua ccuaucagca      240

uuacgcaccg gcugguacac aucaguaaua acaauagaac uauccaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguaaaa uuaauaaaac aagaacucga caaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaaguacuc cagccaccaa caacagagca      420

agaagagaau uaccacgauu uaugaacuac acacuaaaca augcaaaaaa aacaaacgua      480

acacuaucaa aaaaacguaa acgcagauuc uuaggcuucc uccuaggugu aggcucagca      540

aucgccucag gaguggcagu uuguaaagua cuacaccuag aaggagaagu aaacaaaauc      600

aaaucugccc uuuuaucgac aaacaaagca guaguaucgu uauccaaugg agucucagua      660

uugacauuca aaguauuaga ccuaaaaaau uauauagaua aacaacucuu accuaucuua      720

aauaaacaaa gcugcucaau aaguaacaua gaaaccguaa uagaauuuca acaaaaaaac      780

aauagacucc uugagaucac ucgagaauuu ucaguaaacg cagguguaac aacaccagua      840

agcacauaca ugcuaacaaa uagugaacua uuaucucuaa uuaacgauau gcccauaacc      900

aacgaucaaa aaaaacucau gaguaacaac guacaaauag uaagacaaca auccuauagc      960

auaaugugca uuauaaaaga agaaguacua gcauauguag uccaacuacc acuauacggc     1020

guaauagaca caccaugcug gaaacuacac accucacccc uaugcacaac aaauacaaaa     1080

gaaggaucaa acauaugcuu aaccaggaca gacagaggcu gguacugcga uaacgcagga     1140

ucuguuucau ucuuccccca agcagaaaca ugcaaaguac aaucaaacag aguauuuugu     1200

gauaccauga acucacucac auuaccaucc gaagucaacc ucugcaacgu agacauauuc     1260

aaccccaaau acgacugcaa aauaaugacc ucaaaaacag auguaucauc aucaguaauc     1320

acaucacuag gagcuaucgu aucuuguuau ggaaaaacaa aaugcacagc auccaacaaa     1380

aacagaggaa uuaucaaaac auucucaaau ggaugugacu auguaucaaa caaaggagua     1440

gacaccguaa gcguaggcaa uacacuauau uacguaaaua aacaagaagg aaaaucacua     1500

uacguaaaag gugaaccaau aauaaacuuc uaugaccccc uaguauuccc aucagaugaa     1560

uuugacgcaa gcauaucaca agucaacgaa aaaauaaacc aaucacuggc auucauucgc     1620

aaaucagaug aacuucucca caacguaaac gcugguaaaa gcacuacaaa cauaaugaua     1680

acaacaauca ucauugucau aauaguuauu cuauuaucac uaaucgcagu aggauuacua     1740

cuauacugua aagcgaggua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1579
<211>  2256
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1579
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccacaau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgaaccg gcugguacac cuccgugauc accaucgagc ugucaaacau caaggagaac      300

aagugcaacg ggaccgaugc caagguuaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccacuc cggcaaccaa caaccgcgcc      420

aggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaaugug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccuaggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug uugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc gugguaagcc ucuccaacgg cgucagcguu      660

cugaccuuca aggugcugga ccucaagaac uauaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cucaaacauc gaaacgguga uugaguucca gcagaagaac      780

aaccggcucc uggaaaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cuaucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga agaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcacaac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccucu gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagacag acgugagcuc cagcgugauc     1320

acaucccugg gggccaucgu cagcugcuac ggcaagacua aguguacugc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacguuaaua agcaggaggg caagagccuc     1500

uacgugaaag gggagcccau cauuaacuuc uacgacccac ugguuuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauu cugcuguccc ucaucgccgu ggggcugcug     1740

cuuuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1800

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1860

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1920

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1980

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     2040

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2100

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2220

ccccccccaa aggcucuuuu cagagccacc agaauu                               2256


<210>  1580
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1580
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccaa caaccgcgcc      420

cggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccugggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      780

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1320

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1500

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1740

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1581
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1581
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccaa caaccgggcc      420

cgccgggagc ugccgcgcuu caugaacuac acccucaaca acgccaagaa gacgaacgug      480

acccugagca agaagcggaa gcgccgguuc cugggcuucc uccugggggu gggcuccgcg      540

aucgccagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      600

aaguccgccc ugcugagcac caacaaggcc gugguguccc ucagcaacgg cgucuccgug      660

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccuc      720

aacaagcaga gcugcuccau cagcaacauc gagacgguca ucgaguucca gcagaagaac      780

aaccgccugc uggagaucac ccgggaguuc uccgugaacg cgggggugac cacccccguc      840

agcacguaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugcgccagca guccuacagc      960

aucaugugca ucaucaagga ggagguccug gccuacgugg ugcagcuccc gcuguacggc     1020

gucaucgaca cccccugcug gaagcugcac acgagccccc ucugcaccac caacaccaag     1080

gaggggagca acaucugccu gacgcggacc gaccgcggcu gguacugcga caacgccggc     1140

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg gguguucugc     1200

gacaccauga acagccugac gcucccgucc gaggugaacc ugugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgugauc     1320

accagccugg gggccaucgu cuccugcuac ggcaagacga agugcaccgc gagcaacaag     1380

aaccgcggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguca gcguggggaa cacccucuac uacgugaaca agcaggaggg caagucccug     1500

uacgucaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1560

uucgacgccu ccaucagcca ggugaacgag aagaucaacc agucccucgc cuucauccgg     1620

aaguccgacg agcugcugca caacgucaac gccggcaagu ccacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcucagcc ugaucgccgu cgggcugcuc     1740

cuguacugca aggcgcgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1582
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1582
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccaa caaccgcgcc      420

cgccgcgagc ucccccgcuu caugaacuac acccucaaca acgccaagaa gaccaacguc      480

acccucucca agaagcgcaa gcgccgcuuc cucggcuucc uccucggcgu cggcuccgcc      540

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      600

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      660

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      720

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      780

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      840

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      900

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      960

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc     1020

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag     1080

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1140

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1200

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1320

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1380

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1440

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1500

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1560

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1620

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1680

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1740

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1583
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1583
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccaa caauagggcu      420

cggcgcgagu ugccucgauu uaugaacuac acgcucaaua acgcaaagaa aacuaaugug      480

acccugucga agaaacguaa gagaagguuc cugggcuuuc ucuuaggggu cggaucagcc      540

auagcuagcg gcguggccgu uuguaaggug cugcaccuug aaggugaggu caacaaaauc      600

aagagugcgu ugcuguccac aaauaaagca gugguaucuc uaagcaacgg gguuuccgug      660

cucacuuuca agguccugga ccuuaaaaau uauauugaua agcaacuguu gccaauccuc      720

aacaaacagu caugcaguau uagcaacauc gaaaccguga uagaguuuca gcagaagaau      780

aaccggcugu uagagauuac acgcgaguuc ucugugaaug ccggagucac cacgccgguu      840

uccacuuaca ugcugacaaa cucagaacuc cuuagccuga ucaaugacau gcccauuacc      900

aacgaucaaa agaaauugau gaguaauaac gugcagaucg uaagacagca gucuuauucc      960

aucaugugua uuauaaagga agaggugcua gcuuacgucg ugcaacugcc ucucuacggc     1020

guuaucgaca cuccaugcug gaaacugcau acaagccccc uuuguaccac gaauaccaag     1080

gaaggcucga acauuugccu gacaaggacu gaucgggggu gguauuguga caaugccgga     1140

ucuguguccu uuuucccuca ggcagagacc ugcaaagucc agucaaaccg cguguuuugu     1200

gauacaauga auaguuugac ucucccaagc gagguaaacc ugugcaaugu ugacaucuuc     1260

aaccccaagu acgauugcaa gauaaugacc uccaaaacag acgugucuag cucagucauu     1320

accaguuuag gugcuaucgu guccuguuau ggcaagacua aaugcacggc cagcaacaag     1380

aaucgaggga ucauuaaaac auuuucuaac ggaugugauu acgucucaaa uaagggcgug     1440

gacaccguua guguggguaa cacucuguau uacguaaaua agcaagaagg gaaaagccua     1500

uaugucaagg gagagccuau cauuaacuuc uacgacccac ucguguuccc guccgaugaa     1560

uuugacgcgu cuauaucgca gguuaaugag aaaaucaacc agagccuggc cuucauuaga     1620

aaguccgaug aacuuuugca caaugugaac gcaggcaaau caaccacaaa uaucaugauc     1680

accacuauua uaaucgucau uaucgugauu cugcucaguc ugaucgcugu aggccuucug     1740

uuguacugca aggccaggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1584
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1584
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccaa caacagagcc      420

agaagagagc ugcccagauu caugaacuac acccugaaca acgccaagaa gaccaacgug      480

acccugagca agaagagaaa gagaagauuc cugggcuucc ugcugggcgu gggcagcgcc      540

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      600

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      660

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      780

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      840

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      900

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      960

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc     1020

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag     1080

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1140

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1200

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1320

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1380

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1500

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1560

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1620

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1740

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1585
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1585
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacaaa caaucgggcu      420

cgcagagagc ucccucgguu uaugaacuac acccugaaua acgccaagaa aacaaauguc      480

acccuuucua agaaacgcaa gagacgguuc cugggguuuc uccugggagu gggcagcgcg      540

auugccuccg ggguugcugu guguaagguc cuucaccugg aaggagaggu gaacaaaauc      600

aagagcgccc uccugucuac gaauaaagcu guuguguccc ugagcaacgg cgucucugug      660

cucacauuca aggugcugga ccuuaaaaau uauauugaua agcaacugcu cccgauccug      720

aacaaacagu ccugcagcau uucuaacauc gaaaccguca uugaguuuca gcagaagaau      780

aaccgccuuc uggagaucac aagagaauuu uccguuaaug ccggcgugac cacccccgug      840

agcacauaca ugcucacgaa cuccgagcug cugucucuca ucaaugacau gccuauuacc      900

aacgaucaaa agaaacugau gagcaauaac guccagaucg ugcggcagca guccuauagc      960

auuaugugua ucauuaagga agagguucuu gcguacgugg uccaacugcc ccucuacggg     1020

gugaucgaca caccuugcug gaaacugcau accucucccc uuuguacaac caauacgaag     1080

gaaggaucca acaucugccu gacacgcacc gauagaggcu gguauuguga caaugccggg     1140

agcguuucuu ucuucccuca ggcugagacc ugcaaagugc agagcaaccg ggucuuuugu     1200

gauacaauga acucccucac ccugccgucu gaggugaauc ugugcaaugu cgacauuuuc     1260

aaccccaagu acgauugcaa gaucaugaca agcaaaacgg acguguccag cucuguuauu     1320

accucccucg gagccaucgu gagcuguuau ggcaagacaa aaugcaccgc uucuaacaag     1380

aaucgcggga uuaucaaaac auuuuccaac ggaugugauu acgucagcaa uaagggcgug     1440

gacaccguuu ccgugggcaa cacgcuguau uacgucaaua agcaagaagg gaaaucucuu     1500

uaugugaagg gagagccuau cauuaacuuc uacgaccccc ugguguuccc uagcgaugaa     1560

uuugacgccu ccaucucuca gguuaaugag aaaauuaacc agagccucgc cuucaucaga     1620

aaguccgaug aacugcugca caaugucaac gcuggcaaaa gcaccacaaa uauuaugauc     1680

accacaauua ucaucgugau uaucgugauu cuucucucuc ugaucgcggu cgggcugcuc     1740

cuguacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1586
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1586
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaaugcua uuaccacaau acuuacugcu guaaccuucu gcuuugccuc uggccaaaac      180

auaacagaag aauuuuauca aucaacuugc uccgcuguaa gcaaaggcua ccuaucagca      240

uuacgcaccg gcugguacac aucaguaaua acaauagaac uauccaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguaaaa uuaauaaaac aagaacucga caaauacaaa      360

aacgcaguaa cagaauuaca acuacuaaug caaaguacuc cagccaccaa caacagagca      420

agaagagaau uaccacgauu uaugaacuac acacuaaaca augcaaaaaa aacaaacgua      480

acacuaucaa aaaaacguaa acgcagauuc uuaggcuucc uccuaggugu aggcucagca      540

aucgccucag gaguggcagu uuguaaagua cuacaccuag aaggagaagu aaacaaaauc      600

aaaucugccc uuuuaucgac aaacaaagca guaguaucgu uauccaaugg agucucagua      660

uugacauuca aaguauuaga ccuaaaaaau uauauagaua aacaacucuu accuaucuua      720

aauaaacaaa gcugcucaau aaguaacaua gaaaccguaa uagaauuuca acaaaaaaac      780

aauagacucc uugagaucac ucgagaauuu ucaguaaacg cagguguaac aacaccagua      840

agcacauaca ugcuaacaaa uagugaacua uuaucucuaa uuaacgauau gcccauaacc      900

aacgaucaaa aaaaacucau gaguaacaac guacaaauag uaagacaaca auccuauagc      960

auaaugugca uuauaaaaga agaaguacua gcauauguag uccaacuacc acuauacggc     1020

guaauagaca caccaugcug gaaacuacac accucacccc uaugcacaac aaauacaaaa     1080

gaaggaucaa acauaugcuu aaccaggaca gacagaggcu gguacugcga uaacgcagga     1140

ucuguuucau ucuuccccca agcagaaaca ugcaaaguac aaucaaacag aguauuuugu     1200

gauaccauga acucacucac auuaccaucc gaagucaacc ucugcaacgu agacauauuc     1260

aaccccaaau acgacugcaa aauaaugacc ucaaaaacag auguaucauc aucaguaauc     1320

acaucacuag gagcuaucgu aucuuguuau ggaaaaacaa aaugcacagc auccaacaaa     1380

aacagaggaa uuaucaaaac auucucaaau ggaugugacu auguaucaaa caaaggagua     1440

gacaccguaa gcguaggcaa uacacuauau uacguaaaua aacaagaagg aaaaucacua     1500

uacguaaaag gugaaccaau aauaaacuuc uaugaccccc uaguauuccc aucagaugaa     1560

uuugacgcaa gcauaucaca agucaacgaa aaaauaaacc aaucacuggc auucauucgc     1620

aaaucagaug aacuucucca caacguaaac gcugguaaaa gcacuacaaa cauaaugaua     1680

acaacaauca ucauugucau aauaguuauu cuauuaucac uaaucgcagu aggauuacua     1740

cuauacugua aagcgaggua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1587
<211>  2036
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1587
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccacaau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgaaccg gcugguacac cuccgugauc accaucgagc ugucaaacau caaggagaac      300

aagugcaacg ggaccgaugc caagguuaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccacuc cggcaaccaa caaccgcgcc      420

aggcgcgagc ugccccgguu caugaacuac acccucaaca acgccaagaa gacgaaugug      480

acccugagca agaagcgcaa gcggcgcuuc cugggcuucc uccuaggggu gggcuccgcc      540

aucgcgagcg gcgucgccgu gugcaaggug uugcaccucg agggggaggu caacaagauc      600

aagagcgccc ugcuguccac caacaaggcc gugguaagcc ucuccaacgg cgucagcguu      660

cugaccuuca aggugcugga ccucaagaac uauaucgaca agcagcugcu gcccauccug      720

aacaagcaga gcugcuccau cucaaacauc gaaacgguga uugaguucca gcagaagaac      780

aaccggcucc uggaaaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      840

uccacguaca ugcugaccaa cagcgagcuc cuaucccuga ucaacgacau gccgaucacc      900

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      960

aucaugugca ucaucaagga agaggugcug gcguacgugg uccagcugcc ccucuacggc     1020

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcacaac caacaccaag     1080

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1140

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1200

gacaccauga acucccugac gcugcccucu gagguaaacc ucugcaacgu cgacaucuuc     1260

aaccccaagu acgacugcaa gaucaugacc uccaagacag acgugagcuc cagcgugauc     1320

acaucccugg gggccaucgu cagcugcuac ggcaagacua aguguacugc cagcaacaag     1380

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1440

gacaccgugu ccgucgggaa cacccuguac uacguuaaua agcaggaggg caagagccuc     1500

uacgugaaag gggagcccau cauuaacuuc uacgacccac ugguuuuccc cuccgacgag     1560

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1620

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1680

accaccauca ucaucgugau caucgugauu cugcuguccc ucaucgccgu ggggcugcug     1740

cuuuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1800

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1860

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1980

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         2036


<210>  1588
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1588
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1589
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1589
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1590
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1590
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1591
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1591
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1592
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1592
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1593
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1593
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cggugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1594
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1594
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa ugcuauuacc acaauacuua cugcuguaac cuucugcuuu      240

gccucuggcc aaaacauaac agaagaauuu uaucaaucaa cuugcuccgc uguaagcaaa      300

ggcuaccuau cagcauuacg caccggcugg uacacaucag uaauaacaau agaacuaucc      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uaaaauuaau aaaacaagaa      420

cucgacaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaaag uacuccagcc      480

accaacaaca gagcaagaag agaauuacca cgauuuauga acuacacacu aaacaaugca      540

aaaaaaacaa acguaacacu aucaaaaaaa cguaaacgca gauucuuagg cuuccuccua      600

gguguaggcu cagcaaucgc cucaggagug gcaguuugua aaguacuaca ccuagaagga      660

gaaguaaaca aaaucaaauc ugcccuuuua ucgacaaaca aagcaguagu aucguuaucc      720

aauggagucu caguauugac auucaaagua uuagaccuaa aaaauuauau agauaaacaa      780

cucuuaccua ucuuaaauaa acaaagcugc ucaauaagua acauagaaac cguaauagaa      840

uuucaacaaa aaaacaauag acuccuugag aucacucgag aauuuucagu aaacgcaggu      900

guaacaacac caguaagcac auacaugcua acaaauagug aacuauuauc ucuaauuaac      960

gauaugccca uaaccaacga ucaaaaaaaa cucaugagua acaacguaca aauaguaaga     1020

caacaauccu auagcauaau gugcauuaua aaagaagaag uacuagcaua uguaguccaa     1080

cuaccacuau acggcguaau agacacacca ugcuggaaac uacacaccuc accccuaugc     1140

acaacaaaua caaaagaagg aucaaacaua ugcuuaacca ggacagacag aggcugguac     1200

ugcgauaacg caggaucugu uucauucuuc ccccaagcag aaacaugcaa aguacaauca     1260

aacagaguau uuugugauac caugaacuca cucacauuac cauccgaagu caaccucugc     1320

aacguagaca uauucaaccc caaauacgac ugcaaaauaa ugaccucaaa aacagaugua     1380

ucaucaucag uaaucacauc acuaggagcu aucguaucuu guuauggaaa aacaaaaugc     1440

acagcaucca acaaaaacag aggaauuauc aaaacauucu caaauggaug ugacuaugua     1500

ucaaacaaag gaguagacac cguaagcgua ggcaauacac uauauuacgu aaauaaacaa     1560

gaaggaaaau cacuauacgu aaaaggugaa ccaauaauaa acuucuauga cccccuagua     1620

uucccaucag augaauuuga cgcaagcaua ucacaaguca acgaaaaaau aaaccaauca     1680

cuggcauuca uucgcaaauc agaugaacuu cuccacaacg uaaacgcugg uaaaagcacu     1740

acaaacauaa ugauaacaac aaucaucauu gucauaauag uuauucuauu aucacuaauc     1800

gcaguaggau uacuacuaua cuguaaagcg agguaaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1595
<211>  2099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1595
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc acaauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg aaccggcugg uacaccuccg ugaucaccau cgagcuguca      360

aacaucaagg agaacaagug caacgggacc gaugccaagg uuaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacuccggca      480

accaacaacc gcgccaggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga augugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccua      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca agguguugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu aagccucucc      720

aacggcguca gcguucugac cuucaaggug cuggaccuca agaacuauau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucucaa acaucgaaac ggugauugag      840

uuccagcaga agaacaaccg gcuccuggaa aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuauc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaagagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

acaaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccucugaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gacagacgug     1380

agcuccagcg ugaucacauc ccugggggcc aucgucagcu gcuacggcaa gacuaagugu     1440

acugccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu uaauaagcag     1560

gagggcaaga gccucuacgu gaaaggggag cccaucauua acuucuacga cccacugguu     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauucugcu gucccucauc     1800

gccguggggc ugcugcuuua cugcaaggcc cggugaggac uaguaauaag gaaacuguau     1860

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug     1920

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     2040

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      2099


<210>  1596
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1596
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1597
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1597
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1598
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1598
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1599
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1599
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1600
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1600
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1601
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1601
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cggugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1602
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1602
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa ugcuauuacc acaauacuua cugcuguaac cuucugcuuu      240

gccucuggcc aaaacauaac agaagaauuu uaucaaucaa cuugcuccgc uguaagcaaa      300

ggcuaccuau cagcauuacg caccggcugg uacacaucag uaauaacaau agaacuaucc      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uaaaauuaau aaaacaagaa      420

cucgacaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaaag uacuccagcc      480

accaacaaca gagcaagaag agaauuacca cgauuuauga acuacacacu aaacaaugca      540

aaaaaaacaa acguaacacu aucaaaaaaa cguaaacgca gauucuuagg cuuccuccua      600

gguguaggcu cagcaaucgc cucaggagug gcaguuugua aaguacuaca ccuagaagga      660

gaaguaaaca aaaucaaauc ugcccuuuua ucgacaaaca aagcaguagu aucguuaucc      720

aauggagucu caguauugac auucaaagua uuagaccuaa aaaauuauau agauaaacaa      780

cucuuaccua ucuuaaauaa acaaagcugc ucaauaagua acauagaaac cguaauagaa      840

uuucaacaaa aaaacaauag acuccuugag aucacucgag aauuuucagu aaacgcaggu      900

guaacaacac caguaagcac auacaugcua acaaauagug aacuauuauc ucuaauuaac      960

gauaugccca uaaccaacga ucaaaaaaaa cucaugagua acaacguaca aauaguaaga     1020

caacaauccu auagcauaau gugcauuaua aaagaagaag uacuagcaua uguaguccaa     1080

cuaccacuau acggcguaau agacacacca ugcuggaaac uacacaccuc accccuaugc     1140

acaacaaaua caaaagaagg aucaaacaua ugcuuaacca ggacagacag aggcugguac     1200

ugcgauaacg caggaucugu uucauucuuc ccccaagcag aaacaugcaa aguacaauca     1260

aacagaguau uuugugauac caugaacuca cucacauuac cauccgaagu caaccucugc     1320

aacguagaca uauucaaccc caaauacgac ugcaaaauaa ugaccucaaa aacagaugua     1380

ucaucaucag uaaucacauc acuaggagcu aucguaucuu guuauggaaa aacaaaaugc     1440

acagcaucca acaaaaacag aggaauuauc aaaacauucu caaauggaug ugacuaugua     1500

ucaaacaaag gaguagacac cguaagcgua ggcaauacac uauauuacgu aaauaaacaa     1560

gaaggaaaau cacuauacgu aaaaggugaa ccaauaauaa acuucuauga cccccuagua     1620

uucccaucag augaauuuga cgcaagcaua ucacaaguca acgaaaaaau aaaccaauca     1680

cuggcauuca uucgcaaauc agaugaacuu cuccacaacg uaaacgcugg uaaaagcacu     1740

acaaacauaa ugauaacaac aaucaucauu gucauaauag uuauucuauu aucacuaauc     1800

gcaguaggau uacuacuaua cuguaaagcg agguaaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1603
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1603
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc acaauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg aaccggcugg uacaccuccg ugaucaccau cgagcuguca      360

aacaucaagg agaacaagug caacgggacc gaugccaagg uuaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacuccggca      480

accaacaacc gcgccaggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga augugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccua      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca agguguugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu aagccucucc      720

aacggcguca gcguucugac cuucaaggug cuggaccuca agaacuauau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucucaa acaucgaaac ggugauugag      840

uuccagcaga agaacaaccg gcuccuggaa aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuauc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaagagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

acaaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccucugaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gacagacgug     1380

agcuccagcg ugaucacauc ccugggggcc aucgucagcu gcuacggcaa gacuaagugu     1440

acugccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu uaauaagcag     1560

gagggcaaga gccucuacgu gaaaggggag cccaucauua acuucuacga cccacugguu     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauucugcu gucccucauc     1800

gccguggggc ugcugcuuua cugcaaggcc cggugaggac uaguacuggc ugcaucuccc     1860

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc     1920

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag     1980

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2100

agagccacca gaauu                                                      2115


<210>  1604
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1604
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accaacaacc gcgcccggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccug      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu gagccucucc      720

aacggcguca gcgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucagca acaucgagac ggugaucgag      840

uuccagcaga agaacaaccg gcuccuggag aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuguc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

accaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccagcgaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacgug     1380

agcuccagcg ugaucaccuc ccugggggcc aucgucagcu gcuacggcaa gacgaagugc     1440

accgccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccucuacgu gaagggggag cccaucauca acuucuacga cccgcugguc     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ugauccugcu gucccucauc     1800

gccguggggc ugcugcucua cugcaaggcc cggugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1605
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1605
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accaacaacc gggcccgccg ggagcugccg cgcuucauga acuacacccu caacaacgcc      540

aagaagacga acgugacccu gagcaagaag cggaagcgcc gguuccuggg cuuccuccug      600

ggggugggcu ccgcgaucgc cagcggcguc gccgugugca aggugcugca ccucgagggg      660

gaggucaaca agaucaaguc cgcccugcug agcaccaaca aggccguggu gucccucagc      720

aacggcgucu ccgugcugac cuucaaggug cuggaccuca agaacuacau cgacaagcag      780

cugcugccca uccucaacaa gcagagcugc uccaucagca acaucgagac ggucaucgag      840

uuccagcaga agaacaaccg ccugcuggag aucacccggg aguucuccgu gaacgcgggg      900

gugaccaccc ccgucagcac guacaugcuc accaacagcg agcugcuguc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugcgc     1020

cagcaguccu acagcaucau gugcaucauc aaggaggagg uccuggccua cguggugcag     1080

cucccgcugu acggcgucau cgacaccccc ugcuggaagc ugcacacgag cccccucugc     1140

accaccaaca ccaaggaggg gagcaacauc ugccugacgc ggaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu gagcuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgggugu ucugcgacac caugaacagc cugacgcucc cguccgaggu gaaccugugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

uccagcuccg ugaucaccag ccugggggcc aucgucuccu gcuacggcaa gacgaagugc     1440

accgcgagca acaagaaccg cgggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgucagcgug gggaacaccc ucuacuacgu gaacaagcag     1560

gagggcaagu cccuguacgu caagggggag cccaucauca acuucuacga cccccuggug     1620

uucccgagcg acgaguucga cgccuccauc agccagguga acgagaagau caaccagucc     1680

cucgccuuca uccggaaguc cgacgagcug cugcacaacg ucaacgccgg caaguccacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu cagccugauc     1800

gccgucgggc ugcuccugua cugcaaggcg cgcugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1606
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1606
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accaacaacc gcgcccgccg cgagcucccc cgcuucauga acuacacccu caacaacgcc      540

aagaagacca acgucacccu cuccaagaag cgcaagcgcc gcuuccucgg cuuccuccuc      600

ggcgucggcu ccgccaucgc cuccggcguc gccgucugca agguccucca ccucgagggc      660

gaggucaaca agaucaaguc cgcccuccuc uccaccaaca aggccgucgu cucccucucc      720

aacggcgucu ccguccucac cuucaagguc cucgaccuca agaacuacau cgacaagcag      780

cuccucccca uccucaacaa gcaguccugc uccaucucca acaucgagac cgucaucgag      840

uuccagcaga agaacaaccg ccuccucgag aucacccgcg aguucuccgu caacgccggc      900

gucaccaccc ccgucuccac cuacaugcuc accaacuccg agcuccucuc ccucaucaac      960

gacaugccca ucaccaacga ccagaagaag cucaugucca acaacgucca gaucguccgc     1020

cagcaguccu acuccaucau gugcaucauc aaggaggagg uccucgccua cgucguccag     1080

cucccccucu acggcgucau cgacaccccc ugcuggaagc uccacaccuc cccccucugc     1140

accaccaaca ccaaggaggg cuccaacauc ugccucaccc gcaccgaccg cggcugguac     1200

ugcgacaacg ccggcuccgu cuccuucuuc ccccaggccg agaccugcaa gguccagucc     1260

aaccgcgucu ucugcgacac caugaacucc cucacccucc ccuccgaggu caaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gaccgacguc     1380

uccuccuccg ucaucaccuc ccucggcgcc aucgucuccu gcuacggcaa gaccaagugc     1440

accgccucca acaagaaccg cggcaucauc aagaccuucu ccaacggcug cgacuacguc     1500

uccaacaagg gcgucgacac cgucuccguc ggcaacaccc ucuacuacgu caacaagcag     1560

gagggcaagu cccucuacgu caagggcgag cccaucauca acuucuacga cccccucguc     1620

uuccccuccg acgaguucga cgccuccauc ucccagguca acgagaagau caaccagucc     1680

cucgccuuca uccgcaaguc cgacgagcuc cuccacaacg ucaacgccgg caaguccacc     1740

accaacauca ugaucaccac caucaucauc gucaucaucg ucauccuccu cucccucauc     1800

gccgucggcc uccuccucua cugcaaggcc cgcugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1607
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1607
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accaacaaua gggcucggcg cgaguugccu cgauuuauga acuacacgcu caauaacgca      540

aagaaaacua augugacccu gucgaagaaa cguaagagaa gguuccuggg cuuucucuua      600

ggggucggau cagccauagc uagcggcgug gccguuugua aggugcugca ccuugaaggu      660

gaggucaaca aaaucaagag ugcguugcug uccacaaaua aagcaguggu aucucuaagc      720

aacgggguuu ccgugcucac uuucaagguc cuggaccuua aaaauuauau ugauaagcaa      780

cuguugccaa uccucaacaa acagucaugc aguauuagca acaucgaaac cgugauagag      840

uuucagcaga agaauaaccg gcuguuagag auuacacgcg aguucucugu gaaugccgga      900

gucaccacgc cgguuuccac uuacaugcug acaaacucag aacuccuuag ccugaucaau      960

gacaugccca uuaccaacga ucaaaagaaa uugaugagua auaacgugca gaucguaaga     1020

cagcagucuu auuccaucau guguauuaua aaggaagagg ugcuagcuua cgucgugcaa     1080

cugccucucu acggcguuau cgacacucca ugcuggaaac ugcauacaag cccccuuugu     1140

accacgaaua ccaaggaagg cucgaacauu ugccugacaa ggacugaucg ggggugguau     1200

ugugacaaug ccggaucugu guccuuuuuc ccucaggcag agaccugcaa aguccaguca     1260

aaccgcgugu uuugugauac aaugaauagu uugacucucc caagcgaggu aaaccugugc     1320

aauguugaca ucuucaaccc caaguacgau ugcaagauaa ugaccuccaa aacagacgug     1380

ucuagcucag ucauuaccag uuuaggugcu aucguguccu guuauggcaa gacuaaaugc     1440

acggccagca acaagaaucg agggaucauu aaaacauuuu cuaacggaug ugauuacguc     1500

ucaaauaagg gcguggacac cguuagugug gguaacacuc uguauuacgu aaauaagcaa     1560

gaagggaaaa gccuauaugu caagggagag ccuaucauua acuucuacga cccacucgug     1620

uucccguccg augaauuuga cgcgucuaua ucgcagguua augagaaaau caaccagagc     1680

cuggccuuca uuagaaaguc cgaugaacuu uugcacaaug ugaacgcagg caaaucaacc     1740

acaaauauca ugaucaccac uauuauaauc gucauuaucg ugauucugcu cagucugauc     1800

gcuguaggcc uucuguugua cugcaaggcc aggugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1608
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1608
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accaacaaca gagccagaag agagcugccc agauucauga acuacacccu gaacaacgcc      540

aagaagacca acgugacccu gagcaagaag agaaagagaa gauuccuggg cuuccugcug      600

ggcgugggca gcgccaucgc cagcggcgug gccgugugca aggugcugca ccuggagggc      660

gaggugaaca agaucaagag cgcccugcug agcaccaaca aggccguggu gagccugagc      720

aacggcguga gcgugcugac cuucaaggug cuggaccuga agaacuacau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc agcaucagca acaucgagac cgugaucgag      840

uuccagcaga agaacaacag acugcuggag aucaccagag aguucagcgu gaacgccggc      900

gugaccaccc ccgugagcac cuacaugcug accaacagcg agcugcugag ccugaucaac      960

gacaugccca ucaccaacga ccagaagaag cugaugagca acaacgugca gaucgugaga     1020

cagcagagcu acagcaucau gugcaucauc aaggaggagg ugcuggccua cguggugcag     1080

cugccccugu acggcgugau cgacaccccc ugcuggaagc ugcacaccag cccccugugc     1140

accaccaaca ccaaggaggg cagcaacauc ugccugacca gaaccgacag aggcugguac     1200

ugcgacaacg ccggcagcgu gagcuucuuc ccccaggccg agaccugcaa ggugcagagc     1260

aacagagugu ucugcgacac caugaacagc cugacccugc ccagcgaggu gaaccugugc     1320

aacguggaca ucuucaaccc caaguacgac ugcaagauca ugaccagcaa gaccgacgug     1380

agcagcagcg ugaucaccag ccugggcgcc aucgugagcu gcuacggcaa gaccaagugc     1440

accgccagca acaagaacag aggcaucauc aagaccuuca gcaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cgugagcgug ggcaacaccc uguacuacgu gaacaagcag     1560

gagggcaaga gccuguacgu gaagggcgag cccaucauca acuucuacga cccccuggug     1620

uuccccagcg acgaguucga cgccagcauc agccagguga acgagaagau caaccagagc     1680

cuggccuuca ucagaaagag cgacgagcug cugcacaacg ugaacgccgg caagagcacc     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauccugcu gagccugauc     1800

gccgugggcc ugcugcugua cugcaaggcc agaugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1609
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1609
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acaaacaauc gggcucgcag agagcucccu cgguuuauga acuacacccu gaauaacgcc      540

aagaaaacaa augucacccu uucuaagaaa cgcaagagac gguuccuggg guuucuccug      600

ggagugggca gcgcgauugc cuccgggguu gcugugugua agguccuuca ccuggaagga      660

gaggugaaca aaaucaagag cgcccuccug ucuacgaaua aagcuguugu gucccugagc      720

aacggcgucu cugugcucac auucaaggug cuggaccuua aaaauuauau ugauaagcaa      780

cugcucccga uccugaacaa acaguccugc agcauuucua acaucgaaac cgucauugag      840

uuucagcaga agaauaaccg ccuucuggag aucacaagag aauuuuccgu uaaugccggc      900

gugaccaccc ccgugagcac auacaugcuc acgaacuccg agcugcuguc ucucaucaau      960

gacaugccua uuaccaacga ucaaaagaaa cugaugagca auaacgucca gaucgugcgg     1020

cagcaguccu auagcauuau guguaucauu aaggaagagg uucuugcgua cgugguccaa     1080

cugccccucu acggggugau cgacacaccu ugcuggaaac ugcauaccuc uccccuuugu     1140

acaaccaaua cgaaggaagg auccaacauc ugccugacac gcaccgauag aggcugguau     1200

ugugacaaug ccgggagcgu uucuuucuuc ccucaggcug agaccugcaa agugcagagc     1260

aaccgggucu uuugugauac aaugaacucc cucacccugc cgucugaggu gaaucugugc     1320

aaugucgaca uuuucaaccc caaguacgau ugcaagauca ugacaagcaa aacggacgug     1380

uccagcucug uuauuaccuc ccucggagcc aucgugagcu guuauggcaa gacaaaaugc     1440

accgcuucua acaagaaucg cgggauuauc aaaacauuuu ccaacggaug ugauuacguc     1500

agcaauaagg gcguggacac cguuuccgug ggcaacacgc uguauuacgu caauaagcaa     1560

gaagggaaau cucuuuaugu gaagggagag ccuaucauua acuucuacga cccccuggug     1620

uucccuagcg augaauuuga cgccuccauc ucucagguua augagaaaau uaaccagagc     1680

cucgccuuca ucagaaaguc cgaugaacug cugcacaaug ucaacgcugg caaaagcacc     1740

acaaauauua ugaucaccac aauuaucauc gugauuaucg ugauucuucu cucucugauc     1800

gcggucgggc ugcuccugua cugcaaggcc cggugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1610
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1610
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa ugcuauuacc acaauacuua cugcuguaac cuucugcuuu      240

gccucuggcc aaaacauaac agaagaauuu uaucaaucaa cuugcuccgc uguaagcaaa      300

ggcuaccuau cagcauuacg caccggcugg uacacaucag uaauaacaau agaacuaucc      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uaaaauuaau aaaacaagaa      420

cucgacaaau acaaaaacgc aguaacagaa uuacaacuac uaaugcaaag uacuccagcc      480

accaacaaca gagcaagaag agaauuacca cgauuuauga acuacacacu aaacaaugca      540

aaaaaaacaa acguaacacu aucaaaaaaa cguaaacgca gauucuuagg cuuccuccua      600

gguguaggcu cagcaaucgc cucaggagug gcaguuugua aaguacuaca ccuagaagga      660

gaaguaaaca aaaucaaauc ugcccuuuua ucgacaaaca aagcaguagu aucguuaucc      720

aauggagucu caguauugac auucaaagua uuagaccuaa aaaauuauau agauaaacaa      780

cucuuaccua ucuuaaauaa acaaagcugc ucaauaagua acauagaaac cguaauagaa      840

uuucaacaaa aaaacaauag acuccuugag aucacucgag aauuuucagu aaacgcaggu      900

guaacaacac caguaagcac auacaugcua acaaauagug aacuauuauc ucuaauuaac      960

gauaugccca uaaccaacga ucaaaaaaaa cucaugagua acaacguaca aauaguaaga     1020

caacaauccu auagcauaau gugcauuaua aaagaagaag uacuagcaua uguaguccaa     1080

cuaccacuau acggcguaau agacacacca ugcuggaaac uacacaccuc accccuaugc     1140

acaacaaaua caaaagaagg aucaaacaua ugcuuaacca ggacagacag aggcugguac     1200

ugcgauaacg caggaucugu uucauucuuc ccccaagcag aaacaugcaa aguacaauca     1260

aacagaguau uuugugauac caugaacuca cucacauuac cauccgaagu caaccucugc     1320

aacguagaca uauucaaccc caaauacgac ugcaaaauaa ugaccucaaa aacagaugua     1380

ucaucaucag uaaucacauc acuaggagcu aucguaucuu guuauggaaa aacaaaaugc     1440

acagcaucca acaaaaacag aggaauuauc aaaacauucu caaauggaug ugacuaugua     1500

ucaaacaaag gaguagacac cguaagcgua ggcaauacac uauauuacgu aaauaaacaa     1560

gaaggaaaau cacuauacgu aaaaggugaa ccaauaauaa acuucuauga cccccuagua     1620

uucccaucag augaauuuga cgcaagcaua ucacaaguca acgaaaaaau aaaccaauca     1680

cuggcauuca uucgcaaauc agaugaacuu cuccacaacg uaaacgcugg uaaaagcacu     1740

acaaacauaa ugauaacaac aaucaucauu gucauaauag uuauucuauu aucacuaauc     1800

gcaguaggau uacuacuaua cuguaaagcg agguaaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1611
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1611
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc acaauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg aaccggcugg uacaccuccg ugaucaccau cgagcuguca      360

aacaucaagg agaacaagug caacgggacc gaugccaagg uuaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacuccggca      480

accaacaacc gcgccaggcg cgagcugccc cgguucauga acuacacccu caacaacgcc      540

aagaagacga augugacccu gagcaagaag cgcaagcggc gcuuccuggg cuuccuccua      600

ggggugggcu ccgccaucgc gagcggcguc gccgugugca agguguugca ccucgagggg      660

gaggucaaca agaucaagag cgcccugcug uccaccaaca aggccguggu aagccucucc      720

aacggcguca gcguucugac cuucaaggug cuggaccuca agaacuauau cgacaagcag      780

cugcugccca uccugaacaa gcagagcugc uccaucucaa acaucgaaac ggugauugag      840

uuccagcaga agaacaaccg gcuccuggaa aucacccgcg aguucagcgu gaacgccggg      900

gucaccaccc ccguguccac guacaugcug accaacagcg agcuccuauc ccugaucaac      960

gacaugccga ucaccaacga ccagaagaag cucaugagca acaacgugca gaucguccgg     1020

cagcaguccu acagcaucau gugcaucauc aaggaagagg ugcuggcgua cgugguccag     1080

cugccccucu acggcgugau cgacaccccc ugcuggaagc ugcacacgag cccccugugc     1140

acaaccaaca ccaaggaggg guccaacauc ugccucacgc gcaccgaccg gggcugguac     1200

ugcgacaacg ccggcagcgu cuccuucuuc ccgcaggccg agaccugcaa ggugcagagc     1260

aaccgcgugu ucugcgacac caugaacucc cugacgcugc ccucugaggu aaaccucugc     1320

aacgucgaca ucuucaaccc caaguacgac ugcaagauca ugaccuccaa gacagacgug     1380

agcuccagcg ugaucacauc ccugggggcc aucgucagcu gcuacggcaa gacuaagugu     1440

acugccagca acaagaaccg ggggaucauc aagaccuucu ccaacggcug cgacuacgug     1500

agcaacaagg gcguggacac cguguccguc gggaacaccc uguacuacgu uaauaagcag     1560

gagggcaaga gccucuacgu gaaaggggag cccaucauua acuucuacga cccacugguu     1620

uuccccuccg acgaguucga cgcgagcauc ucccagguga acgagaagau caaccagagc     1680

cuggccuuca uccgcaaguc cgacgagcug cuccacaacg ugaacgccgg caagagcacg     1740

accaacauca ugaucaccac caucaucauc gugaucaucg ugauucugcu gucccucauc     1800

gccguggggc ugcugcuuua cugcaaggcc cggugaggac uaguguccac cugucccucc     1860

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1612
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1612
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cugggggugg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1613
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1613
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccaaca accgggcccg ccgggagcug ccgcgcuuca ugaacuacac ccucaacaac      420

gccaagaaga cgaacgugac ccugagcaag aagcggaagc gccgguuccu gggcuuccuc      480

cugggggugg gcuccgcgau cgccagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa guccgcccug cugagcacca acaaggccgu ggugucccuc      600

agcaacggcg ucuccgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccucaa caagcagagc ugcuccauca gcaacaucga gacggucauc      720

gaguuccagc agaagaacaa ccgccugcug gagaucaccc gggaguucuc cgugaacgcg      780

ggggugacca cccccgucag cacguacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

cgccagcagu ccuacagcau caugugcauc aucaaggagg agguccuggc cuacguggug      960

cagcucccgc uguacggcgu caucgacacc cccugcugga agcugcacac gagcccccuc     1020

ugcaccacca acaccaagga ggggagcaac aucugccuga cgcggaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccggg uguucugcga caccaugaac agccugacgc ucccguccga ggugaaccug     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgugaucac cagccugggg gccaucgucu ccugcuacgg caagacgaag     1320

ugcaccgcga gcaacaagaa ccgcgggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgucagc guggggaaca cccucuacua cgugaacaag     1440

caggagggca agucccugua cgucaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ugaacgagaa gaucaaccag     1560

ucccucgccu ucauccggaa guccgacgag cugcugcaca acgucaacgc cggcaagucc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcucagccug     1680

aucgccgucg ggcugcuccu guacugcaag gcgcgcugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1614
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1614
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccaaca accgcgcccg ccgcgagcuc ccccgcuuca ugaacuacac ccucaacaac      420

gccaagaaga ccaacgucac ccucuccaag aagcgcaagc gccgcuuccu cggcuuccuc      480

cucggcgucg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1615
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1615
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccaaca auagggcucg gcgcgaguug ccucgauuua ugaacuacac gcucaauaac      420

gcaaagaaaa cuaaugugac ccugucgaag aaacguaaga gaagguuccu gggcuuucuc      480

uuaggggucg gaucagccau agcuagcggc guggccguuu guaaggugcu gcaccuugaa      540

ggugagguca acaaaaucaa gagugcguug cuguccacaa auaaagcagu gguaucucua      600

agcaacgggg uuuccgugcu cacuuucaag guccuggacc uuaaaaauua uauugauaag      660

caacuguugc caauccucaa caaacaguca ugcaguauua gcaacaucga aaccgugaua      720

gaguuucagc agaagaauaa ccggcuguua gagauuacac gcgaguucuc ugugaaugcc      780

ggagucacca cgccgguuuc cacuuacaug cugacaaacu cagaacuccu uagccugauc      840

aaugacaugc ccauuaccaa cgaucaaaag aaauugauga guaauaacgu gcagaucgua      900

agacagcagu cuuauuccau cauguguauu auaaaggaag aggugcuagc uuacgucgug      960

caacugccuc ucuacggcgu uaucgacacu ccaugcugga aacugcauac aagcccccuu     1020

uguaccacga auaccaagga aggcucgaac auuugccuga caaggacuga ucgggggugg     1080

uauugugaca augccggauc uguguccuuu uucccucagg cagagaccug caaaguccag     1140

ucaaaccgcg uguuuuguga uacaaugaau aguuugacuc ucccaagcga gguaaaccug     1200

ugcaauguug acaucuucaa ccccaaguac gauugcaaga uaaugaccuc caaaacagac     1260

gugucuagcu cagucauuac caguuuaggu gcuaucgugu ccuguuaugg caagacuaaa     1320

ugcacggcca gcaacaagaa ucgagggauc auuaaaacau uuucuaacgg augugauuac     1380

gucucaaaua agggcgugga caccguuagu guggguaaca cucuguauua cguaaauaag     1440

caagaaggga aaagccuaua ugucaaggga gagccuauca uuaacuucua cgacccacuc     1500

guguucccgu ccgaugaauu ugacgcgucu auaucgcagg uuaaugagaa aaucaaccag     1560

agccuggccu ucauuagaaa guccgaugaa cuuuugcaca augugaacgc aggcaaauca     1620

accacaaaua ucaugaucac cacuauuaua aucgucauua ucgugauucu gcucagucug     1680

aucgcuguag gccuucuguu guacugcaag gccaggugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1616
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1616
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccaaca acagagccag aagagagcug cccagauuca ugaacuacac ccugaacaac      420

gccaagaaga ccaacgugac ccugagcaag aagagaaaga gaagauuccu gggcuuccug      480

cugggcgugg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1617
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1617
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacaaaca aucgggcucg cagagagcuc ccucgguuua ugaacuacac ccugaauaac      420

gccaagaaaa caaaugucac ccuuucuaag aaacgcaaga gacgguuccu gggguuucuc      480

cugggagugg gcagcgcgau ugccuccggg guugcugugu guaagguccu ucaccuggaa      540

ggagagguga acaaaaucaa gagcgcccuc cugucuacga auaaagcugu ugugucccug      600

agcaacggcg ucucugugcu cacauucaag gugcuggacc uuaaaaauua uauugauaag      660

caacugcucc cgauccugaa caaacagucc ugcagcauuu cuaacaucga aaccgucauu      720

gaguuucagc agaagaauaa ccgccuucug gagaucacaa gagaauuuuc cguuaaugcc      780

ggcgugacca cccccgugag cacauacaug cucacgaacu ccgagcugcu gucucucauc      840

aaugacaugc cuauuaccaa cgaucaaaag aaacugauga gcaauaacgu ccagaucgug      900

cggcagcagu ccuauagcau uauguguauc auuaaggaag agguucuugc guacgugguc      960

caacugcccc ucuacggggu gaucgacaca ccuugcugga aacugcauac cucuccccuu     1020

uguacaacca auacgaagga aggauccaac aucugccuga cacgcaccga uagaggcugg     1080

uauugugaca augccgggag cguuucuuuc uucccucagg cugagaccug caaagugcag     1140

agcaaccggg ucuuuuguga uacaaugaac ucccucaccc ugccgucuga ggugaaucug     1200

ugcaaugucg acauuuucaa ccccaaguac gauugcaaga ucaugacaag caaaacggac     1260

guguccagcu cuguuauuac cucccucgga gccaucguga gcuguuaugg caagacaaaa     1320

ugcaccgcuu cuaacaagaa ucgcgggauu aucaaaacau uuuccaacgg augugauuac     1380

gucagcaaua agggcgugga caccguuucc gugggcaaca cgcuguauua cgucaauaag     1440

caagaaggga aaucucuuua ugugaaggga gagccuauca uuaacuucua cgacccccug     1500

guguucccua gcgaugaauu ugacgccucc aucucucagg uuaaugagaa aauuaaccag     1560

agccucgccu ucaucagaaa guccgaugaa cugcugcaca augucaacgc uggcaaaagc     1620

accacaaaua uuaugaucac cacaauuauc aucgugauua ucgugauucu ucucucucug     1680

aucgcggucg ggcugcuccu guacugcaag gcccggugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1618
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1618
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuauuaa uauuaaaagc aaaugcuauu accacaauac uuacugcugu aaccuucugc      120

uuugccucug gccaaaacau aacagaagaa uuuuaucaau caacuugcuc cgcuguaagc      180

aaaggcuacc uaucagcauu acgcaccggc ugguacacau caguaauaac aauagaacua      240

uccaacauaa aagaaaauaa augcaacgga acagacgcaa aaguaaaauu aauaaaacaa      300

gaacucgaca aauacaaaaa cgcaguaaca gaauuacaac uacuaaugca aaguacucca      360

gccaccaaca acagagcaag aagagaauua ccacgauuua ugaacuacac acuaaacaau      420

gcaaaaaaaa caaacguaac acuaucaaaa aaacguaaac gcagauucuu aggcuuccuc      480

cuagguguag gcucagcaau cgccucagga guggcaguuu guaaaguacu acaccuagaa      540

ggagaaguaa acaaaaucaa aucugcccuu uuaucgacaa acaaagcagu aguaucguua      600

uccaauggag ucucaguauu gacauucaaa guauuagacc uaaaaaauua uauagauaaa      660

caacucuuac cuaucuuaaa uaaacaaagc ugcucaauaa guaacauaga aaccguaaua      720

gaauuucaac aaaaaaacaa uagacuccuu gagaucacuc gagaauuuuc aguaaacgca      780

gguguaacaa caccaguaag cacauacaug cuaacaaaua gugaacuauu aucucuaauu      840

aacgauaugc ccauaaccaa cgaucaaaaa aaacucauga guaacaacgu acaaauagua      900

agacaacaau ccuauagcau aaugugcauu auaaaagaag aaguacuagc auauguaguc      960

caacuaccac uauacggcgu aauagacaca ccaugcugga aacuacacac cucaccccua     1020

ugcacaacaa auacaaaaga aggaucaaac auaugcuuaa ccaggacaga cagaggcugg     1080

uacugcgaua acgcaggauc uguuucauuc uucccccaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuuguga uaccaugaac ucacucacau uaccauccga agucaaccuc     1200

ugcaacguag acauauucaa ccccaaauac gacugcaaaa uaaugaccuc aaaaacagau     1260

guaucaucau caguaaucac aucacuagga gcuaucguau cuuguuaugg aaaaacaaaa     1320

ugcacagcau ccaacaaaaa cagaggaauu aucaaaacau ucucaaaugg augugacuau     1380

guaucaaaca aaggaguaga caccguaagc guaggcaaua cacuauauua cguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaaggu gaaccaauaa uaaacuucua ugacccccua     1500

guauucccau cagaugaauu ugacgcaagc auaucacaag ucaacgaaaa aauaaaccaa     1560

ucacuggcau ucauucgcaa aucagaugaa cuucuccaca acguaaacgc ugguaaaagc     1620

acuacaaaca uaaugauaac aacaaucauc auugucauaa uaguuauucu auuaucacua     1680

aucgcaguag gauuacuacu auacuguaaa gcgagguaag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1619
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1619
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accacaaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgaaccggc ugguacaccu ccgugaucac caucgagcug      240

ucaaacauca aggagaacaa gugcaacggg accgaugcca agguuaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccacuccg      360

gcaaccaaca accgcgccag gcgcgagcug ccccgguuca ugaacuacac ccucaacaac      420

gccaagaaga cgaaugugac ccugagcaag aagcgcaagc ggcgcuuccu gggcuuccuc      480

cuaggggugg gcuccgccau cgcgagcggc gucgccgugu gcaagguguu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu gguaagccuc      600

uccaacggcg ucagcguucu gaccuucaag gugcuggacc ucaagaacua uaucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucu caaacaucga aacggugauu      720

gaguuccagc agaagaacaa ccggcuccug gaaaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu aucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggaag aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcacaacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccucuga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagacagac     1260

gugagcucca gcgugaucac aucccugggg gccaucguca gcugcuacgg caagacuaag     1320

uguacugcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cguuaauaag     1440

caggagggca agagccucua cgugaaaggg gagcccauca uuaacuucua cgacccacug     1500

guuuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgugauca ucgugauucu gcugucccuc     1680

aucgccgugg ggcugcugcu uuacugcaag gcccggugag gacuagugca ucacauuuaa     1740

aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau     1800

cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu     1860

aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  1620
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1) R6122

<400>  1620
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccaacaaccg cgcccggcgc gagcugcccc gguucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc gcaagcggcg cuuccugggc uuccuccugg      480

gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug agccucucca      600

acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg gugaucgagu      720

uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug aacgccgggg      780

ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc cugaucaacg      840

acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag aucguccggc      900

agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac gugguccagc      960

ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc ccccugugca     1020

ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg ggcugguacu     1080

gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag gugcagagca     1140

accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacguga     1260

gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag acgaagugca     1320

ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac ccgcuggucu     1500

uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc aagagcacga     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug ucccucaucg     1680

ccguggggcu gcugcucuac ugcaaggccc ggugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1621
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1621
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccaacaaccg ggcccgccgg gagcugccgc gcuucaugaa cuacacccuc aacaacgcca      420

agaagacgaa cgugacccug agcaagaagc ggaagcgccg guuccugggc uuccuccugg      480

gggugggcuc cgcgaucgcc agcggcgucg ccgugugcaa ggugcugcac cucgaggggg      540

aggucaacaa gaucaagucc gcccugcuga gcaccaacaa ggccguggug ucccucagca      600

acggcgucuc cgugcugacc uucaaggugc uggaccucaa gaacuacauc gacaagcagc      660

ugcugcccau ccucaacaag cagagcugcu ccaucagcaa caucgagacg gucaucgagu      720

uccagcagaa gaacaaccgc cugcuggaga ucacccggga guucuccgug aacgcggggg      780

ugaccacccc cgucagcacg uacaugcuca ccaacagcga gcugcugucc cucaucaacg      840

acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag aucgugcgcc      900

agcaguccua cagcaucaug ugcaucauca aggaggaggu ccuggccuac guggugcagc      960

ucccgcugua cggcgucauc gacacccccu gcuggaagcu gcacacgagc ccccucugca     1020

ccaccaacac caaggagggg agcaacaucu gccugacgcg gaccgaccgc ggcugguacu     1080

gcgacaacgc cggcuccgug agcuucuucc cccaggccga gaccugcaag guccagucca     1140

accggguguu cugcgacacc augaacagcc ugacgcuccc guccgaggug aaccugugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag accgacgugu     1260

ccagcuccgu gaucaccagc cugggggcca ucgucuccug cuacggcaag acgaagugca     1320

ccgcgagcaa caagaaccgc gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc gucagcgugg ggaacacccu cuacuacgug aacaagcagg     1440

agggcaaguc ccuguacguc aagggggagc ccaucaucaa cuucuacgac ccccuggugu     1500

ucccgagcga cgaguucgac gccuccauca gccaggugaa cgagaagauc aaccaguccc     1560

ucgccuucau ccggaagucc gacgagcugc ugcacaacgu caacgccggc aaguccacga     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcuc agccugaucg     1680

ccgucgggcu gcuccuguac ugcaaggcgc gcugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1622
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1622
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccaacaaccg cgcccgccgc gagcuccccc gcuucaugaa cuacacccuc aacaacgcca      420

agaagaccaa cgucacccuc uccaagaagc gcaagcgccg cuuccucggc uuccuccucg      480

gcgucggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac cucgagggcg      540

aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc ucccucucca      600

acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc gacaagcagc      660

uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc gucaucgagu      720

uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc aacgccggcg      780

ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc cucaucaacg      840

acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag aucguccgcc      900

agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac gucguccagc      960

ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc ccccucugca     1020

ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc ggcugguacu     1080

gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag guccagucca     1140

accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag accgacgucu     1260

ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag accaagugca     1320

ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc gacuacgucu     1380

ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc aacaagcagg     1440

agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac ccccucgucu     1500

uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc aaccaguccc     1560

ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc aaguccacca     1620

ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc ucccucaucg     1680

ccgucggccu ccuccucuac ugcaaggccc gcugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1623
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1623
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccaacaauag ggcucggcgc gaguugccuc gauuuaugaa cuacacgcuc aauaacgcaa      420

agaaaacuaa ugugacccug ucgaagaaac guaagagaag guuccugggc uuucucuuag      480

gggucggauc agccauagcu agcggcgugg ccguuuguaa ggugcugcac cuugaaggug      540

aggucaacaa aaucaagagu gcguugcugu ccacaaauaa agcaguggua ucucuaagca      600

acgggguuuc cgugcucacu uucaaggucc uggaccuuaa aaauuauauu gauaagcaac      660

uguugccaau ccucaacaaa cagucaugca guauuagcaa caucgaaacc gugauagagu      720

uucagcagaa gaauaaccgg cuguuagaga uuacacgcga guucucugug aaugccggag      780

ucaccacgcc gguuuccacu uacaugcuga caaacucaga acuccuuagc cugaucaaug      840

acaugcccau uaccaacgau caaaagaaau ugaugaguaa uaacgugcag aucguaagac      900

agcagucuua uuccaucaug uguauuauaa aggaagaggu gcuagcuuac gucgugcaac      960

ugccucucua cggcguuauc gacacuccau gcuggaaacu gcauacaagc ccccuuugua     1020

ccacgaauac caaggaaggc ucgaacauuu gccugacaag gacugaucgg gggugguauu     1080

gugacaaugc cggaucugug uccuuuuucc cucaggcaga gaccugcaaa guccagucaa     1140

accgcguguu uugugauaca augaauaguu ugacucuccc aagcgaggua aaccugugca     1200

auguugacau cuucaacccc aaguacgauu gcaagauaau gaccuccaaa acagacgugu     1260

cuagcucagu cauuaccagu uuaggugcua ucguguccug uuauggcaag acuaaaugca     1320

cggccagcaa caagaaucga gggaucauua aaacauuuuc uaacggaugu gauuacgucu     1380

caaauaaggg cguggacacc guuagugugg guaacacucu guauuacgua aauaagcaag     1440

aagggaaaag ccuauauguc aagggagagc cuaucauuaa cuucuacgac ccacucgugu     1500

ucccguccga ugaauuugac gcgucuauau cgcagguuaa ugagaaaauc aaccagagcc     1560

uggccuucau uagaaagucc gaugaacuuu ugcacaaugu gaacgcaggc aaaucaacca     1620

caaauaucau gaucaccacu auuauaaucg ucauuaucgu gauucugcuc agucugaucg     1680

cuguaggccu ucuguuguac ugcaaggcca ggugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1624
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1624
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccaacaacag agccagaaga gagcugccca gauucaugaa cuacacccug aacaacgcca      420

agaagaccaa cgugacccug agcaagaaga gaaagagaag auuccugggc uuccugcugg      480

gcgugggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac cuggagggcg      540

aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug agccugagca      600

acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc gacaagcagc      660

ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc gugaucgagu      720

uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug aacgccggcg      780

ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc cugaucaacg      840

acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag aucgugagac      900

agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac guggugcagc      960

ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc ccccugugca     1020

ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga ggcugguacu     1080

gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag gugcagagca     1140

acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug aaccugugca     1200

acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag accgacguga     1260

gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag accaagugca     1320

ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug aacaagcagg     1440

agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac ccccuggugu     1500

uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc aagagcacca     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug agccugaucg     1680

ccgugggccu gcugcuguac ugcaaggcca gaugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1625
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1625
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

caaacaaucg ggcucgcaga gagcucccuc gguuuaugaa cuacacccug aauaacgcca      420

agaaaacaaa ugucacccuu ucuaagaaac gcaagagacg guuccugggg uuucuccugg      480

gagugggcag cgcgauugcc uccgggguug cuguguguaa gguccuucac cuggaaggag      540

aggugaacaa aaucaagagc gcccuccugu cuacgaauaa agcuguugug ucccugagca      600

acggcgucuc ugugcucaca uucaaggugc uggaccuuaa aaauuauauu gauaagcaac      660

ugcucccgau ccugaacaaa caguccugca gcauuucuaa caucgaaacc gucauugagu      720

uucagcagaa gaauaaccgc cuucuggaga ucacaagaga auuuuccguu aaugccggcg      780

ugaccacccc cgugagcaca uacaugcuca cgaacuccga gcugcugucu cucaucaaug      840

acaugccuau uaccaacgau caaaagaaac ugaugagcaa uaacguccag aucgugcggc      900

agcaguccua uagcauuaug uguaucauua aggaagaggu ucuugcguac gugguccaac      960

ugccccucua cggggugauc gacacaccuu gcuggaaacu gcauaccucu ccccuuugua     1020

caaccaauac gaaggaagga uccaacaucu gccugacacg caccgauaga ggcugguauu     1080

gugacaaugc cgggagcguu ucuuucuucc cucaggcuga gaccugcaaa gugcagagca     1140

accgggucuu uugugauaca augaacuccc ucacccugcc gucugaggug aaucugugca     1200

augucgacau uuucaacccc aaguacgauu gcaagaucau gacaagcaaa acggacgugu     1260

ccagcucugu uauuaccucc cucggagcca ucgugagcug uuauggcaag acaaaaugca     1320

ccgcuucuaa caagaaucgc gggauuauca aaacauuuuc caacggaugu gauuacguca     1380

gcaauaaggg cguggacacc guuuccgugg gcaacacgcu guauuacguc aauaagcaag     1440

aagggaaauc ucuuuaugug aagggagagc cuaucauuaa cuucuacgac ccccuggugu     1500

ucccuagcga ugaauuugac gccuccaucu cucagguuaa ugagaaaauu aaccagagcc     1560

ucgccuucau cagaaagucc gaugaacugc ugcacaaugu caacgcuggc aaaagcacca     1620

caaauauuau gaucaccaca auuaucaucg ugauuaucgu gauucuucuc ucucugaucg     1680

cggucgggcu gcuccuguac ugcaaggccc ggugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1626
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1626
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uauuaauauu aaaagcaaau gcuauuacca caauacuuac ugcuguaacc uucugcuuug      120

ccucuggcca aaacauaaca gaagaauuuu aucaaucaac uugcuccgcu guaagcaaag      180

gcuaccuauc agcauuacgc accggcuggu acacaucagu aauaacaaua gaacuaucca      240

acauaaaaga aaauaaaugc aacggaacag acgcaaaagu aaaauuaaua aaacaagaac      300

ucgacaaaua caaaaacgca guaacagaau uacaacuacu aaugcaaagu acuccagcca      360

ccaacaacag agcaagaaga gaauuaccac gauuuaugaa cuacacacua aacaaugcaa      420

aaaaaacaaa cguaacacua ucaaaaaaac guaaacgcag auucuuaggc uuccuccuag      480

guguaggcuc agcaaucgcc ucaggagugg caguuuguaa aguacuacac cuagaaggag      540

aaguaaacaa aaucaaaucu gcccuuuuau cgacaaacaa agcaguagua ucguuaucca      600

auggagucuc aguauugaca uucaaaguau uagaccuaaa aaauuauaua gauaaacaac      660

ucuuaccuau cuuaaauaaa caaagcugcu caauaaguaa cauagaaacc guaauagaau      720

uucaacaaaa aaacaauaga cuccuugaga ucacucgaga auuuucagua aacgcaggug      780

uaacaacacc aguaagcaca uacaugcuaa caaauaguga acuauuaucu cuaauuaacg      840

auaugcccau aaccaacgau caaaaaaaac ucaugaguaa caacguacaa auaguaagac      900

aacaauccua uagcauaaug ugcauuauaa aagaagaagu acuagcauau guaguccaac      960

uaccacuaua cggcguaaua gacacaccau gcuggaaacu acacaccuca ccccuaugca     1020

caacaaauac aaaagaagga ucaaacauau gcuuaaccag gacagacaga ggcugguacu     1080

gcgauaacgc aggaucuguu ucauucuucc cccaagcaga aacaugcaaa guacaaucaa     1140

acagaguauu uugugauacc augaacucac ucacauuacc auccgaaguc aaccucugca     1200

acguagacau auucaacccc aaauacgacu gcaaaauaau gaccucaaaa acagauguau     1260

caucaucagu aaucacauca cuaggagcua ucguaucuug uuauggaaaa acaaaaugca     1320

cagcauccaa caaaaacaga ggaauuauca aaacauucuc aaauggaugu gacuauguau     1380

caaacaaagg aguagacacc guaagcguag gcaauacacu auauuacgua aauaaacaag     1440

aaggaaaauc acuauacgua aaaggugaac caauaauaaa cuucuaugac ccccuaguau     1500

ucccaucaga ugaauuugac gcaagcauau cacaagucaa cgaaaaaaua aaccaaucac     1560

uggcauucau ucgcaaauca gaugaacuuc uccacaacgu aaacgcuggu aaaagcacua     1620

caaacauaau gauaacaaca aucaucauug ucauaauagu uauucuauua ucacuaaucg     1680

caguaggauu acuacuauac uguaaagcga gguaaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1627
<211>  2044
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1627
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca caauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcga accggcuggu acaccuccgu gaucaccauc gagcugucaa      240

acaucaagga gaacaagugc aacgggaccg augccaaggu uaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acuccggcaa      360

ccaacaaccg cgccaggcgc gagcugcccc gguucaugaa cuacacccuc aacaacgcca      420

agaagacgaa ugugacccug agcaagaagc gcaagcggcg cuuccugggc uuccuccuag      480

gggugggcuc cgccaucgcg agcggcgucg ccgugugcaa gguguugcac cucgaggggg      540

aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggua agccucucca      600

acggcgucag cguucugacc uucaaggugc uggaccucaa gaacuauauc gacaagcagc      660

ugcugcccau ccugaacaag cagagcugcu ccaucucaaa caucgaaacg gugauugagu      720

uccagcagaa gaacaaccgg cuccuggaaa ucacccgcga guucagcgug aacgccgggg      780

ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccuaucc cugaucaacg      840

acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag aucguccggc      900

agcaguccua cagcaucaug ugcaucauca aggaagaggu gcuggcguac gugguccagc      960

ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc ccccugugca     1020

caaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg ggcugguacu     1080

gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag gugcagagca     1140

accgcguguu cugcgacacc augaacuccc ugacgcugcc cucugaggua aaccucugca     1200

acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag acagacguga     1260

gcuccagcgu gaucacaucc cugggggcca ucgucagcug cuacggcaag acuaagugua     1320

cugccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc gacuacguga     1380

gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacguu aauaagcagg     1440

agggcaagag ccucuacgug aaaggggagc ccaucauuaa cuucuacgac ccacugguuu     1500

uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc aaccagagcc     1560

uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc aagagcacga     1620

ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauucugcug ucccucaucg     1680

ccguggggcu gcugcuuuac ugcaaggccc ggugaggacu agugcaucac auuuaaaagc     1740

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1800

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1860

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2040

aauu                                                                  2044


<210>  1628
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1) R5453

<400>  1628
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccaacaac cgcgcccggc gcgagcugcc ccgguucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcgcaagcgg      420

cgcuuccugg gcuuccuccu gggggugggc uccgccaucg cgagcggcgu cgccgugugc      480

aaggugcugc accucgaggg ggaggucaac aagaucaaga gcgcccugcu guccaccaac      540

aaggccgugg ugagccucuc caacggcguc agcgugcuga ccuucaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      660

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      720

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      780

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      840

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      900

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      960

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg     1020

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1080

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1140

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1260

ugcuacggca agacgaagug caccgccagc aacaagaacc gggggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1440

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1560

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1620

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1629
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1)

<400>  1629
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccaacaac cgggcccgcc gggagcugcc gcgcuucaug      360

aacuacaccc ucaacaacgc caagaagacg aacgugaccc ugagcaagaa gcggaagcgc      420

cgguuccugg gcuuccuccu gggggugggc uccgcgaucg ccagcggcgu cgccgugugc      480

aaggugcugc accucgaggg ggaggucaac aagaucaagu ccgcccugcu gagcaccaac      540

aaggccgugg ugucccucag caacggcguc uccgugcuga ccuucaaggu gcuggaccuc      600

aagaacuaca ucgacaagca gcugcugccc auccucaaca agcagagcug cuccaucagc      660

aacaucgaga cggucaucga guuccagcag aagaacaacc gccugcugga gaucacccgg      720

gaguucuccg ugaacgcggg ggugaccacc cccgucagca cguacaugcu caccaacagc      780

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      840

aacaacgugc agaucgugcg ccagcagucc uacagcauca ugugcaucau caaggaggag      900

guccuggccu acguggugca gcucccgcug uacggcguca ucgacacccc cugcuggaag      960

cugcacacga gcccccucug caccaccaac accaaggagg ggagcaacau cugccugacg     1020

cggaccgacc gcggcuggua cugcgacaac gccggcuccg ugagcuucuu cccccaggcc     1080

gagaccugca agguccaguc caaccgggug uucugcgaca ccaugaacag ccugacgcuc     1140

ccguccgagg ugaaccugug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccagca agaccgacgu guccagcucc gugaucacca gccugggggc caucgucucc     1260

ugcuacggca agacgaagug caccgcgagc aacaagaacc gcgggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgucagcgu ggggaacacc     1380

cucuacuacg ugaacaagca ggagggcaag ucccuguacg ucaaggggga gcccaucauc     1440

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccaggug     1500

aacgagaaga ucaaccaguc ccucgccuuc auccggaagu ccgacgagcu gcugcacaac     1560

gucaacgccg gcaaguccac gaccaacauc augaucacca ccaucaucau cgugaucauc     1620

gugauccugc ucagccugau cgccgucggg cugcuccugu acugcaaggc gcgcugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1630
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt2)

<400>  1630
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccaacaac cgcgcccgcc gcgagcuccc ccgcuucaug      360

aacuacaccc ucaacaacgc caagaagacc aacgucaccc ucuccaagaa gcgcaagcgc      420

cgcuuccucg gcuuccuccu cggcgucggc uccgccaucg ccuccggcgu cgccgucugc      480

aagguccucc accucgaggg cgaggucaac aagaucaagu ccgcccuccu cuccaccaac      540

aaggccgucg ucucccucuc caacggcguc uccguccuca ccuucaaggu ccucgaccuc      600

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      660

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      720

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      780

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      840

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      900

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      960

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc     1020

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1080

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1140

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1260

ugcuacggca agaccaagug caccgccucc aacaagaacc gcggcaucau caagaccuuc     1320

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1380

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1440

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1500

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1560

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1620

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1631
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt3)

<400>  1631
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccaacaau agggcucggc gcgaguugcc ucgauuuaug      360

aacuacacgc ucaauaacgc aaagaaaacu aaugugaccc ugucgaagaa acguaagaga      420

agguuccugg gcuuucucuu aggggucgga ucagccauag cuagcggcgu ggccguuugu      480

aaggugcugc accuugaagg ugaggucaac aaaaucaaga gugcguugcu guccacaaau      540

aaagcagugg uaucucuaag caacgggguu uccgugcuca cuuucaaggu ccuggaccuu      600

aaaaauuaua uugauaagca acuguugcca auccucaaca aacagucaug caguauuagc      660

aacaucgaaa ccgugauaga guuucagcag aagaauaacc ggcuguuaga gauuacacgc      720

gaguucucug ugaaugccgg agucaccacg ccgguuucca cuuacaugcu gacaaacuca      780

gaacuccuua gccugaucaa ugacaugccc auuaccaacg aucaaaagaa auugaugagu      840

aauaacgugc agaucguaag acagcagucu uauuccauca uguguauuau aaaggaagag      900

gugcuagcuu acgucgugca acugccucuc uacggcguua ucgacacucc augcuggaaa      960

cugcauacaa gcccccuuug uaccacgaau accaaggaag gcucgaacau uugccugaca     1020

aggacugauc ggggguggua uugugacaau gccggaucug uguccuuuuu cccucaggca     1080

gagaccugca aaguccaguc aaaccgcgug uuuugugaua caaugaauag uuugacucuc     1140

ccaagcgagg uaaaccugug caauguugac aucuucaacc ccaaguacga uugcaagaua     1200

augaccucca aaacagacgu gucuagcuca gucauuacca guuuaggugc uaucgugucc     1260

uguuauggca agacuaaaug cacggccagc aacaagaauc gagggaucau uaaaacauuu     1320

ucuaacggau gugauuacgu cucaaauaag ggcguggaca ccguuagugu ggguaacacu     1380

cuguauuacg uaaauaagca agaagggaaa agccuauaug ucaagggaga gccuaucauu     1440

aacuucuacg acccacucgu guucccgucc gaugaauuug acgcgucuau aucgcagguu     1500

aaugagaaaa ucaaccagag ccuggccuuc auuagaaagu ccgaugaacu uuugcacaau     1560

gugaacgcag gcaaaucaac cacaaauauc augaucacca cuauuauaau cgucauuauc     1620

gugauucugc ucagucugau cgcuguaggc cuucuguugu acugcaaggc caggugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1632
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt4)

<400>  1632
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccaacaac agagccagaa gagagcugcc cagauucaug      360

aacuacaccc ugaacaacgc caagaagacc aacgugaccc ugagcaagaa gagaaagaga      420

agauuccugg gcuuccugcu gggcgugggc agcgccaucg ccagcggcgu ggccgugugc      480

aaggugcugc accuggaggg cgaggugaac aagaucaaga gcgcccugcu gagcaccaac      540

aaggccgugg ugagccugag caacggcgug agcgugcuga ccuucaaggu gcuggaccug      600

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      660

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      720

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      780

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      840

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      900

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      960

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc     1020

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1080

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1140

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1200

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1260

ugcuacggca agaccaagug caccgccagc aacaagaaca gaggcaucau caagaccuuc     1320

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1380

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1440

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1560

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1620

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1633
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt5)

<400>  1633
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacaaacaau cgggcucgca gagagcuccc ucgguuuaug      360

aacuacaccc ugaauaacgc caagaaaaca aaugucaccc uuucuaagaa acgcaagaga      420

cgguuccugg gguuucuccu gggagugggc agcgcgauug ccuccggggu ugcugugugu      480

aagguccuuc accuggaagg agaggugaac aaaaucaaga gcgcccuccu gucuacgaau      540

aaagcuguug ugucccugag caacggcguc ucugugcuca cauucaaggu gcuggaccuu      600

aaaaauuaua uugauaagca acugcucccg auccugaaca aacaguccug cagcauuucu      660

aacaucgaaa ccgucauuga guuucagcag aagaauaacc gccuucugga gaucacaaga      720

gaauuuuccg uuaaugccgg cgugaccacc cccgugagca cauacaugcu cacgaacucc      780

gagcugcugu cucucaucaa ugacaugccu auuaccaacg aucaaaagaa acugaugagc      840

aauaacgucc agaucgugcg gcagcagucc uauagcauua uguguaucau uaaggaagag      900

guucuugcgu acguggucca acugccccuc uacgggguga ucgacacacc uugcuggaaa      960

cugcauaccu cuccccuuug uacaaccaau acgaaggaag gauccaacau cugccugaca     1020

cgcaccgaua gaggcuggua uugugacaau gccgggagcg uuucuuucuu cccucaggcu     1080

gagaccugca aagugcagag caaccggguc uuuugugaua caaugaacuc ccucacccug     1140

ccgucugagg ugaaucugug caaugucgac auuuucaacc ccaaguacga uugcaagauc     1200

augacaagca aaacggacgu guccagcucu guuauuaccu cccucggagc caucgugagc     1260

uguuauggca agacaaaaug caccgcuucu aacaagaauc gcgggauuau caaaacauuu     1320

uccaacggau gugauuacgu cagcaauaag ggcguggaca ccguuuccgu gggcaacacg     1380

cuguauuacg ucaauaagca agaagggaaa ucucuuuaug ugaagggaga gccuaucauu     1440

aacuucuacg acccccuggu guucccuagc gaugaauuug acgccuccau cucucagguu     1500

aaugagaaaa uuaaccagag ccucgccuuc aucagaaagu ccgaugaacu gcugcacaau     1560

gucaacgcug gcaaaagcac cacaaauauu augaucacca caauuaucau cgugauuauc     1620

gugauucuuc ucucucugau cgcggucggg cugcuccugu acugcaaggc ccggugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1634
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt6)

<400>  1634
gggagaaagc uuaccaugga acuauuaaua uuaaaagcaa augcuauuac cacaauacuu       60

acugcuguaa ccuucugcuu ugccucuggc caaaacauaa cagaagaauu uuaucaauca      120

acuugcuccg cuguaagcaa aggcuaccua ucagcauuac gcaccggcug guacacauca      180

guaauaacaa uagaacuauc caacauaaaa gaaaauaaau gcaacggaac agacgcaaaa      240

guaaaauuaa uaaaacaaga acucgacaaa uacaaaaacg caguaacaga auuacaacua      300

cuaaugcaaa guacuccagc caccaacaac agagcaagaa gagaauuacc acgauuuaug      360

aacuacacac uaaacaaugc aaaaaaaaca aacguaacac uaucaaaaaa acguaaacgc      420

agauucuuag gcuuccuccu agguguaggc ucagcaaucg ccucaggagu ggcaguuugu      480

aaaguacuac accuagaagg agaaguaaac aaaaucaaau cugcccuuuu aucgacaaac      540

aaagcaguag uaucguuauc caauggaguc ucaguauuga cauucaaagu auuagaccua      600

aaaaauuaua uagauaaaca acucuuaccu aucuuaaaua aacaaagcug cucaauaagu      660

aacauagaaa ccguaauaga auuucaacaa aaaaacaaua gacuccuuga gaucacucga      720

gaauuuucag uaaacgcagg uguaacaaca ccaguaagca cauacaugcu aacaaauagu      780

gaacuauuau cucuaauuaa cgauaugccc auaaccaacg aucaaaaaaa acucaugagu      840

aacaacguac aaauaguaag acaacaaucc uauagcauaa ugugcauuau aaaagaagaa      900

guacuagcau auguagucca acuaccacua uacggcguaa uagacacacc augcuggaaa      960

cuacacaccu caccccuaug cacaacaaau acaaaagaag gaucaaacau augcuuaacc     1020

aggacagaca gaggcuggua cugcgauaac gcaggaucug uuucauucuu cccccaagca     1080

gaaacaugca aaguacaauc aaacagagua uuuugugaua ccaugaacuc acucacauua     1140

ccauccgaag ucaaccucug caacguagac auauucaacc ccaaauacga cugcaaaaua     1200

augaccucaa aaacagaugu aucaucauca guaaucacau cacuaggagc uaucguaucu     1260

uguuauggaa aaacaaaaug cacagcaucc aacaaaaaca gaggaauuau caaaacauuc     1320

ucaaauggau gugacuaugu aucaaacaaa ggaguagaca ccguaagcgu aggcaauaca     1380

cuauauuacg uaaauaaaca agaaggaaaa ucacuauacg uaaaagguga accaauaaua     1440

aacuucuaug acccccuagu auucccauca gaugaauuug acgcaagcau aucacaaguc     1500

aacgaaaaaa uaaaccaauc acuggcauuc auucgcaaau cagaugaacu ucuccacaac     1560

guaaacgcug guaaaagcac uacaaacaua augauaacaa caaucaucau ugucauaaua     1620

guuauucuau uaucacuaau cgcaguagga uuacuacuau acuguaaagc gagguaagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1635
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt11)

<400>  1635
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac cacaauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gaaccggcug guacaccucc      180

gugaucacca ucgagcuguc aaacaucaag gagaacaagu gcaacgggac cgaugccaag      240

guuaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacuccggc aaccaacaac cgcgccaggc gcgagcugcc ccgguucaug      360

aacuacaccc ucaacaacgc caagaagacg aaugugaccc ugagcaagaa gcgcaagcgg      420

cgcuuccugg gcuuccuccu aggggugggc uccgccaucg cgagcggcgu cgccgugugc      480

aagguguugc accucgaggg ggaggucaac aagaucaaga gcgcccugcu guccaccaac      540

aaggccgugg uaagccucuc caacggcguc agcguucuga ccuucaaggu gcuggaccuc      600

aagaacuaua ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucuca      660

aacaucgaaa cggugauuga guuccagcag aagaacaacc ggcuccugga aaucacccgc      720

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      780

gagcuccuau cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      840

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaagag      900

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      960

cugcacacga gcccccugug cacaaccaac accaaggagg gguccaacau cugccucacg     1020

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1080

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1140

cccucugagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1200

augaccucca agacagacgu gagcuccagc gugaucacau cccugggggc caucgucagc     1260

ugcuacggca agacuaagug uacugccagc aacaagaacc gggggaucau caagaccuuc     1320

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1380

cuguacuacg uuaauaagca ggagggcaag agccucuacg ugaaagggga gcccaucauu     1440

aacuucuacg acccacuggu uuuccccucc gacgaguucg acgcgagcau cucccaggug     1500

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1560

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgugaucauc     1620

gugauucugc ugucccucau cgccgugggg cugcugcuuu acugcaaggc ccggugagga     1680

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1740

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  1636
<211>  535
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1636

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly Ile 
        515                 520                 525             


Asn Asn Ile Ala Phe Ser Asn 
    530                 535 


<210>  1637
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1637
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1560

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacuga                  1608


<210>  1638
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1638
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucugc uccggcgugg ccgugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcgcugcugu ccaccaacaa ggccgugguc      420

agccucucca acggcgugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccgcugua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      900

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu cuacugcguc     1260

aacaagcagg agggccagag ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguccacccc cgugacccug     1560

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  1639
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1639
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1560

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacuga                  1608


<210>  1640
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1640
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuauaugu ucaggcgugg cagucugcaa gguguugcac      360

cucgagggug aaguuaacaa aaucaagagc gcccugcuga guacgaauaa agcugugguc      420

ucccucucua acggggugag cguauuaacu uuuaagguuc uggaccuuaa gaauuacauu      480

gauaaacaau ugcugccuau ccuaaacaag caguccuguu caauuccaaa uaucgagacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuaguguc      600

aacgccggag ugacuacccc ggugagcaca uauaugcuua ccaauucuga acuguugucc      660

cucaucaacg acaugcccau uacgaacgau caaaagaaac ugaugucaaa uaacguccag      720

aucguucgcc agcagagcua caguaucaug ugcauuauaa aggaggaagu guuagcguau      780

guagugcaac ugccucucua cggcgucauc gacacuccau guuggaaacu ucauacaucu      840

ccccugugca ccacuaauac aaaggagggc uccaacauuu guuugacccg aacggaucgu      900

gggugguacu gcgacaaugc aggaagcgug ucguucuuuc cucaggccga aaccuguaag      960

guucagucua acagaguguu cugcgauaca augaacuccc uaacucugcc aucagagguc     1020

aaucucugca auguggacau cuuuaacccc aaauaugauu guaagauaau gaccaguaaa     1080

acagacguaa gcuccucugu uauuacuagc cugggugcua ucgugucaug cuacggcaag     1140

accaaaugua cagccaguaa uaagaacagg gggaucauua agaccuucuc caauggaugc     1200

gauuauguca gcaacaaagg cguggacacu gucucugugg guaauacgcu uuacuguguu     1260

aacaagcaag aggggcaguc acuguaugug aaaggagaac cuaucauuaa cuuuuacgac     1320

ccauugguau ucccgaguga ugaguuugac gcaagcauau cccaggucaa ugaaaagauc     1380

aaccagucuc ucgcuuucau ucggaaaucg gaugagcugu uacacaaugu gaacgccggc     1440

aagagcacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

ucccucaucg cggucggccu gcuuuuguau ugcaaggccc gcucaacacc cgugacccug     1560

aguaaagacc aacucucugg gauaaacaau aucgcauuca gcaacuga                  1608


<210>  1641
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1641
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1560

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  1642
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1642
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagaa uaaaugcaac gggaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuauuugu agcggggucg ccgugugcaa gguucuccac      360

cuggagggag aagugaacaa aaucaagucc gcgcuucuga gcaccaauaa agccgucgug      420

ucucucucca acggcguuag cgugcugaca uuuaaggucc uugaccugaa gaauuacauu      480

gauaaacaac uccugccuau ccugaacaag cagucuuguu ccauuccgaa uaucgagacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      600

aacgcuggcg ucacaacccc cguuucuaca uauaugcuua ccaauuccga acugcucagc      660

cugaucaacg acaugccuau uaccaacgau caaaagaaac uuauguccaa uaacgugcag      720

aucgugagac agcagucuua cagcauuaug ugcaucauua aggaggaagu ccuggccuau      780

gugguucaac ucccccugua cggggugauc gacacaccuu guuggaaacu gcauacgagc      840

ccccucugca ccacaaauac caaggaggga uccaacaucu gucugacacg gaccgaucgc      900

ggcugguacu gcgacaaugc ugggucuguc uccuucuuuc cucaggccga aacguguaag      960

gugcagagca acagaguuuu cugcgauaca augaacucuc uuacccugcc gagcgaggug     1020

aaucucugca augucgacau uuuuaacccc aaauaugauu guaagaucau gaccuccaaa     1080

acagacgugu cuagcuccgu cauuaccagc cugggagcga ucgugucuug cuacggcaag     1140

acaaaaugua cggccuccaa uaagaaccgg gggauuauca agaccuucag caauggaugc     1200

gauuauguuu cuaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuguguu     1260

aacaagcaag aggggcagag ccuguaugug aaaggagaac cuaucauuaa cuuuuacgac     1320

ccccucgucu ucccuuccga ugaguuugac gcuucuauca gccaggugaa ugaaaagauu     1380

aaccaguccc uggccuucau ccgcaaaucu gaugagcugc uccacaaugu gaacgcuggc     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucccugaucg ccguggggcu ccugcuguau ugcaaggcca gaagcacacc cgugacccuu     1560

ucuaaagacc aacucuccgg aauuaacaau aucgcuuuca gcaacuga                  1608


<210>  1643
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1643
auggaacuau uaauacuaaa agcaaacgcu auaacaacaa uacuaacagc agucacauuc       60

ugcuuugcau caggccaaaa caucacagaa gaauuuuacc aaucaacaug cuccgccgua      120

ucgaaaggau accuaggcgc auuaagaacc ggaugguaua caucagucau aacaauugaa      180

cuaucuaaca uaaaagaaaa caaauguaac ggcacagaug ccaaaguaaa acucaucaaa      240

caagaauuag auaaauacaa aaacgcaguc acugaacuac aacucuuaau gcaaucaaca      300

ccugcaacag gaucaggauc agcaauaugc ucaggaguag ccguauguaa aguacuacac      360

cuagaaggag aagucaacaa aauaaaauca gcccuccuaa guacaaacaa agcugucgua      420

ucacuaucca augguguuuc aguacuaacu uucaaaguuc uagaccuaaa aaacuacaua      480

gacaaacaac uacuaccaau acuaaauaaa caaaguuguu cuauacccaa cauagaaacc      540

gucauagaau uucaacaaaa aaauaauaga cuccuagaaa uaacaagaga auuuucaguu      600

aacgcaggug uaacaacccc aguauccacc uauaugcuaa caaauucaga auuacuuucc      660

cuaaucaacg acaugcccau aacaaaugac caaaaaaaau uaaugucaaa caacguccaa      720

auaguucguc aacaaucaua uucaauaaug ugcauaauaa aagaagaagu cuuagccuac      780

guaguacaac uuccccuuua uggaguuauc gacacacccu gcuggaaacu ccacacuuca      840

ccacuaugua cuacaaacac aaaagaagga uccaacaucu gccucacaag aaccgaucga      900

ggaugguacu gugauaacgc cggauccguc ucauucuucc cacaagcaga aacaugcaaa      960

guacaaucaa acagaguauu uugcgacaca augaacuccc ucacauuacc uucugaagua     1020

aaccuaugua auguagacau auucaacccc aaauacgauu gcaaaauaau gacaucaaag     1080

acagauguau caucaagugu caucacaucc cuaggagcaa uugucucaug uuaugguaaa     1140

acaaaaugca ccgcaucaaa uaaaaacaga ggcauaauaa aaaccuucuc aaacgguugu     1200

gacuacguau ccaauaaagg cgucgacaca guaucaguag guaacacauu auauugugua     1260

aacaaacaag aaggacaguc ccuauaugua aaaggagaac caauaaucaa cuucuacgac     1320

ccacuuguuu ucccuucuga ugaauuugac gcaaguauau cacaaguaaa ugaaaaaauc     1380

aaucaaucac uagccuuuau aagaaaauca gaugaauuau uacacaacgu aaacgccgga     1440

aaaucaacaa ccaacauaau gauaaccaca auaauaaucg ucauaauagu cauccuacua     1500

ucacucauag caguuggacu ccuacuauac ugcaaagcac gaucaacacc aguaacauua     1560

uccaaagacc aacuaagugg uaucaauaac aucgccuuuu caaacuga                  1608


<210>  1644
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut1

<400>  1644
auggaacucc uaauccucaa agccaacgca aucaccacaa uccucacugc cgucaccuuc       60

ugcuucgccu ccggccaaaa cauaacagaa gaauuuuacc aaucaaccug uucagcgguc      120

uccaaaggcu accucggcgc ccuccgcacc ggcugguaca ccuccgugau caccauagaa      180

cucuccaaca ucaaggaaaa caaaugcaac ggcaccgacg cgaaggucaa acuuauuaaa      240

caagaacucg acaaauacaa aaacgcaguc accgaacuac aacuccuaau gcaguccacg      300

ccagccaccg gcucuggcuc agccauaugc uccggugugg ccguaugcaa aguccuacac      360

cucgaaggag aagucaacaa aauaaaaucc gcccuacugu ccacaaacaa ggccguaguc      420

ucccucucaa acggcgucuc aguacucacc uucaaagucc uagaccucaa gaacuacauc      480

gacaaacaac uccuacccau acuaaacaaa caauccugcu caauccccaa caucgaaacc      540

guaauagaau uucaacaaaa aaacaacaga cuccuggaga ucacccggga auuuuccgua      600

aacgccggag ucacaacacc cgucucaacc uacaugcuaa cgaacucaga gcuccucuca      660

cuuaucaacg acaugcccau aacaaacgac caaaaaaaac ucauguccaa caacgugcaa      720

aucguccgac aacaauccua cuccaucaug ugcaucauua aagaagaagu ccucgcauac      780

guaguccagc ucccccucua cggcgucaua gacacccccu gcuggaaacu acacacauca      840

ccccucugca caacaaacac caaagaaggc uccaacaucu gccucacccg caccgaccga      900

ggcugguacu gcgauaacgc cggcagcguc uccuucuucc cccaagcaga aaccugcaag      960

guccaaucca accgaguuuu cugcgacacu augaacucgc ucacccuccc cuccgaaguc     1020

aaccucugca acgucgacau uuucaacccc aaauacgacu gcaaaaucau gaccuccaag     1080

accgacguau ccuccuccgu caucaccucc cuaggcgcca uaguaaguug cuacggcaaa     1140

accaagugca cagcaagcaa caaaaaccga ggaauaauca aaaccuucuc caacggcugc     1200

gacuacguau ccaacaaggg cgucgacacc guauccguag ggaacacccu uuacugcgua     1260

aacaaacaag aaggacaauc acucuacgua aaaggcgaac ccauaaucaa cuucuacgac     1320

ccccucguau uucccuccga cgaauuugac gcaucaaucu cacaggucaa cgaaaaaaua     1380

aaccaaucgc uagcauucau cagaaaauca gacgaacucc uacacaacgu caacgcaggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ucauaaucgu cauacuacuc     1500

ucacucauag cagucggccu ccuccuauac uguaaagcaa ggucgacccc agucacccua     1560

uccaaagacc aacuaagcgg caucaacaac aucgcguucu caaacuaa                  1608


<210>  1645
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1645
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1646
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1646
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1647
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1647
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1648
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1648
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaccaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1649
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1649
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1650
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1650
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaccaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1651
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1651
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac      120

uaacagcagu cacauucugc uuugcaucag gccaaaacau cacagaagaa uuuuaccaau      180

caacaugcuc cgccguaucg aaaggauacc uaggcgcauu aagaaccgga ugguauacau      240

cagucauaac aauugaacua ucuaacauaa aagaaaacaa auguaacggc acagaugcca      300

aaguaaaacu caucaaacaa gaauuagaua aauacaaaaa cgcagucacu gaacuacaac      360

ucuuaaugca aucaacaccu gcaacaggau caggaucagc aauaugcuca ggaguagccg      420

uauguaaagu acuacaccua gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua      480

caaacaaagc ugucguauca cuauccaaug guguuucagu acuaacuuuc aaaguucuag      540

accuaaaaaa cuacauagac aaacaacuac uaccaauacu aaauaaacaa aguuguucua      600

uacccaacau agaaaccguc auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa      660

caagagaauu uucaguuaac gcagguguaa caaccccagu auccaccuau augcuaacaa      720

auucagaauu acuuucccua aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa      780

ugucaaacaa cguccaaaua guucgucaac aaucauauuc aauaaugugc auaauaaaag      840

aagaagucuu agccuacgua guacaacuuc cccuuuaugg aguuaucgac acacccugcu      900

ggaaacucca cacuucacca cuauguacua caaacacaaa agaaggaucc aacaucugcc      960

ucacaagaac cgaucgagga ugguacugug auaacgccgg auccgucuca uucuucccac     1020

aagcagaaac augcaaagua caaucaaaca gaguauuuug cgacacaaug aacucccuca     1080

cauuaccuuc ugaaguaaac cuauguaaug uagacauauu caaccccaaa uacgauugca     1140

aaauaaugac aucaaagaca gauguaucau caagugucau cacaucccua ggagcaauug     1200

ucucauguua ugguaaaaca aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa     1260

ccuucucaaa cgguugugac uacguaucca auaaaggcgu cgacacagua ucaguaggua     1320

acacauuaua uuguguaaac aaacaagaag gacagucccu auauguaaaa ggagaaccaa     1380

uaaucaacuu cuacgaccca cuuguuuucc cuucugauga auuugacgca aguauaucac     1440

aaguaaauga aaaaaucaau caaucacuag ccuuuauaag aaaaucagau gaauuauuac     1500

acaacguaaa cgccggaaaa ucaacaacca acauaaugau aaccacaaua auaaucguca     1560

uaauagucau ccuacuauca cucauagcag uuggacuccu acuauacugc aaagcacgau     1620

caacaccagu aacauuaucc aaagaccaac uaagugguau caauaacauc gccuuuucaa     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1652
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1652
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uccucaaagc caacgcaauc accacaaucc      120

ucacugccgu caccuucugc uucgccuccg gccaaaacau aacagaagaa uuuuaccaau      180

caaccuguuc agcggucucc aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgugaucac cauagaacuc uccaacauca aggaaaacaa augcaacggc accgacgcga      300

aggucaaacu uauuaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuacaac      360

uccuaaugca guccacgcca gccaccggcu cuggcucagc cauaugcucc gguguggccg      420

uaugcaaagu ccuacaccuc gaaggagaag ucaacaaaau aaaauccgcc cuacugucca      480

caaacaaggc cguagucucc cucucaaacg gcgucucagu acucaccuuc aaaguccuag      540

accucaagaa cuacaucgac aaacaacucc uacccauacu aaacaaacaa uccugcucaa      600

uccccaacau cgaaaccgua auagaauuuc aacaaaaaaa caacagacuc cuggagauca      660

cccgggaauu uuccguaaac gccggaguca caacacccgu cucaaccuac augcuaacga      720

acucagagcu ccucucacuu aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

uguccaacaa cgugcaaauc guccgacaac aauccuacuc caucaugugc aucauuaaag      840

aagaaguccu cgcauacgua guccagcucc cccucuacgg cgucauagac acccccugcu      900

ggaaacuaca cacaucaccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccgcac cgaccgaggc ugguacugcg auaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cugcaagguc caauccaacc gaguuuucug cgacacuaug aacucgcuca     1080

cccuccccuc cgaagucaac cucugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cuccaagacc gacguauccu ccuccgucau caccucccua ggcgccauag     1200

uaaguugcua cggcaaaacc aagugcacag caagcaacaa aaaccgagga auaaucaaaa     1260

ccuucuccaa cggcugcgac uacguaucca acaagggcgu cgacaccgua uccguaggga     1320

acacccuuua cugcguaaac aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca     1380

uaaucaacuu cuacgacccc cucguauuuc ccuccgacga auuugacgca ucaaucucac     1440

aggucaacga aaaaauaaac caaucgcuag cauucaucag aaaaucagac gaacuccuac     1500

acaacgucaa cgcaggcaag agcaccacca acaucaugau caccaccauc aucaucguca     1560

uaaucgucau acuacucuca cucauagcag ucggccuccu ccuauacugu aaagcaaggu     1620

cgaccccagu cacccuaucc aaagaccaac uaagcggcau caacaacauc gcguucucaa     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  1653
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1653
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1654
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1654
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1655
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1655
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1656
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1656
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaccaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1657
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1657
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1658
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1658
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaccaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1659
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1659
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuaaaagca      120

aacgcuauaa caacaauacu aacagcaguc acauucugcu uugcaucagg ccaaaacauc      180

acagaagaau uuuaccaauc aacaugcucc gccguaucga aaggauaccu aggcgcauua      240

agaaccggau gguauacauc agucauaaca auugaacuau cuaacauaaa agaaaacaaa      300

uguaacggca cagaugccaa aguaaaacuc aucaaacaag aauuagauaa auacaaaaac      360

gcagucacug aacuacaacu cuuaaugcaa ucaacaccug caacaggauc aggaucagca      420

auaugcucag gaguagccgu auguaaagua cuacaccuag aaggagaagu caacaaaaua      480

aaaucagccc uccuaaguac aaacaaagcu gucguaucac uauccaaugg uguuucagua      540

cuaacuuuca aaguucuaga ccuaaaaaac uacauagaca aacaacuacu accaauacua      600

aauaaacaaa guuguucuau acccaacaua gaaaccguca uagaauuuca acaaaaaaau      660

aauagacucc uagaaauaac aagagaauuu ucaguuaacg cagguguaac aaccccagua      720

uccaccuaua ugcuaacaaa uucagaauua cuuucccuaa ucaacgacau gcccauaaca      780

aaugaccaaa aaaaauuaau gucaaacaac guccaaauag uucgucaaca aucauauuca      840

auaaugugca uaauaaaaga agaagucuua gccuacguag uacaacuucc ccuuuaugga      900

guuaucgaca cacccugcug gaaacuccac acuucaccac uauguacuac aaacacaaaa      960

gaaggaucca acaucugccu cacaagaacc gaucgaggau gguacuguga uaacgccgga     1020

uccgucucau ucuucccaca agcagaaaca ugcaaaguac aaucaaacag aguauuuugc     1080

gacacaauga acucccucac auuaccuucu gaaguaaacc uauguaaugu agacauauuc     1140

aaccccaaau acgauugcaa aauaaugaca ucaaagacag auguaucauc aagugucauc     1200

acaucccuag gagcaauugu cucauguuau gguaaaacaa aaugcaccgc aucaaauaaa     1260

aacagaggca uaauaaaaac cuucucaaac gguugugacu acguauccaa uaaaggcguc     1320

gacacaguau caguagguaa cacauuauau uguguaaaca aacaagaagg acagucccua     1380

uauguaaaag gagaaccaau aaucaacuuc uacgacccac uuguuuuccc uucugaugaa     1440

uuugacgcaa guauaucaca aguaaaugaa aaaaucaauc aaucacuagc cuuuauaaga     1500

aaaucagaug aauuauuaca caacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaaucgucau aauagucauc cuacuaucac ucauagcagu uggacuccua     1620

cuauacugca aagcacgauc aacaccagua acauuaucca aagaccaacu aagugguauc     1680

aauaacaucg ccuuuucaaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1660
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1660
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau ccucaaagcc      120

aacgcaauca ccacaauccu cacugccguc accuucugcu ucgccuccgg ccaaaacaua      180

acagaagaau uuuaccaauc aaccuguuca gcggucucca aaggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgugaucacc auagaacucu ccaacaucaa ggaaaacaaa      300

ugcaacggca ccgacgcgaa ggucaaacuu auuaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuacaacu ccuaaugcag uccacgccag ccaccggcuc uggcucagcc      420

auaugcuccg guguggccgu augcaaaguc cuacaccucg aaggagaagu caacaaaaua      480

aaauccgccc uacuguccac aaacaaggcc guagucuccc ucucaaacgg cgucucagua      540

cucaccuuca aaguccuaga ccucaagaac uacaucgaca aacaacuccu acccauacua      600

aacaaacaau ccugcucaau ccccaacauc gaaaccguaa uagaauuuca acaaaaaaac      660

aacagacucc uggagaucac ccgggaauuu uccguaaacg ccggagucac aacacccguc      720

ucaaccuaca ugcuaacgaa cucagagcuc cucucacuua ucaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau guccaacaac gugcaaaucg uccgacaaca auccuacucc      840

aucaugugca ucauuaaaga agaaguccuc gcauacguag uccagcuccc ccucuacggc      900

gucauagaca cccccugcug gaaacuacac acaucacccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccgcacc gaccgaggcu gguacugcga uaacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc ugcaaggucc aauccaaccg aguuuucugc     1080

gacacuauga acucgcucac ccuccccucc gaagucaacc ucugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acguauccuc cuccgucauc     1200

accucccuag gcgccauagu aaguugcuac ggcaaaacca agugcacagc aagcaacaaa     1260

aaccgaggaa uaaucaaaac cuucuccaac ggcugcgacu acguauccaa caagggcguc     1320

gacaccguau ccguagggaa cacccuuuac ugcguaaaca aacaagaagg acaaucacuc     1380

uacguaaaag gcgaacccau aaucaacuuc uacgaccccc ucguauuucc cuccgacgaa     1440

uuugacgcau caaucucaca ggucaacgaa aaaauaaacc aaucgcuagc auucaucaga     1500

aaaucagacg aacuccuaca caacgucaac gcaggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgucau aaucgucaua cuacucucac ucauagcagu cggccuccuc     1620

cuauacugua aagcaagguc gaccccaguc acccuaucca aagaccaacu aagcggcauc     1680

aacaacaucg cguucucaaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  1661
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1661
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1662
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1662
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1663
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1663
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1664
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1664
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaccaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1665
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1665
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1666
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1666
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaccaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1667
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1667
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uaaaagcaaa cgcuauaaca acaauacuaa cagcagucac auucugcuuu      240

gcaucaggcc aaaacaucac agaagaauuu uaccaaucaa caugcuccgc cguaucgaaa      300

ggauaccuag gcgcauuaag aaccggaugg uauacaucag ucauaacaau ugaacuaucu      360

aacauaaaag aaaacaaaug uaacggcaca gaugccaaag uaaaacucau caaacaagaa      420

uuagauaaau acaaaaacgc agucacugaa cuacaacucu uaaugcaauc aacaccugca      480

acaggaucag gaucagcaau augcucagga guagccguau guaaaguacu acaccuagaa      540

ggagaaguca acaaaauaaa aucagcccuc cuaaguacaa acaaagcugu cguaucacua      600

uccaauggug uuucaguacu aacuuucaaa guucuagacc uaaaaaacua cauagacaaa      660

caacuacuac caauacuaaa uaaacaaagu uguucuauac ccaacauaga aaccgucaua      720

gaauuucaac aaaaaaauaa uagacuccua gaaauaacaa gagaauuuuc aguuaacgca      780

gguguaacaa ccccaguauc caccuauaug cuaacaaauu cagaauuacu uucccuaauc      840

aacgacaugc ccauaacaaa ugaccaaaaa aaauuaaugu caaacaacgu ccaaauaguu      900

cgucaacaau cauauucaau aaugugcaua auaaaagaag aagucuuagc cuacguagua      960

caacuucccc uuuauggagu uaucgacaca cccugcugga aacuccacac uucaccacua     1020

uguacuacaa acacaaaaga aggauccaac aucugccuca caagaaccga ucgaggaugg     1080

uacugugaua acgccggauc cgucucauuc uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuugcga cacaaugaac ucccucacau uaccuucuga aguaaaccua     1200

uguaauguag acauauucaa ccccaaauac gauugcaaaa uaaugacauc aaagacagau     1260

guaucaucaa gugucaucac aucccuagga gcaauugucu cauguuaugg uaaaacaaaa     1320

ugcaccgcau caaauaaaaa cagaggcaua auaaaaaccu ucucaaacgg uugugacuac     1380

guauccaaua aaggcgucga cacaguauca guagguaaca cauuauauug uguaaacaaa     1440

caagaaggac agucccuaua uguaaaagga gaaccaauaa ucaacuucua cgacccacuu     1500

guuuucccuu cugaugaauu ugacgcaagu auaucacaag uaaaugaaaa aaucaaucaa     1560

ucacuagccu uuauaagaaa aucagaugaa uuauuacaca acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua aucgucauaa uagucauccu acuaucacuc     1680

auagcaguug gacuccuacu auacugcaaa gcacgaucaa caccaguaac auuauccaaa     1740

gaccaacuaa gugguaucaa uaacaucgcc uuuucaaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1668
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1668
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaaucc ucaaagccaa cgcaaucacc acaauccuca cugccgucac cuucugcuuc      240

gccuccggcc aaaacauaac agaagaauuu uaccaaucaa ccuguucagc ggucuccaaa      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ugaucaccau agaacucucc      360

aacaucaagg aaaacaaaug caacggcacc gacgcgaagg ucaaacuuau uaaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuacaacucc uaaugcaguc cacgccagcc      480

accggcucug gcucagccau augcuccggu guggccguau gcaaaguccu acaccucgaa      540

ggagaaguca acaaaauaaa auccgcccua cuguccacaa acaaggccgu agucucccuc      600

ucaaacggcg ucucaguacu caccuucaaa guccuagacc ucaagaacua caucgacaaa      660

caacuccuac ccauacuaaa caaacaaucc ugcucaaucc ccaacaucga aaccguaaua      720

gaauuucaac aaaaaaacaa cagacuccug gagaucaccc gggaauuuuc cguaaacgcc      780

ggagucacaa cacccgucuc aaccuacaug cuaacgaacu cagagcuccu cucacuuauc      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu ccaacaacgu gcaaaucguc      900

cgacaacaau ccuacuccau caugugcauc auuaaagaag aaguccucgc auacguaguc      960

cagcuccccc ucuacggcgu cauagacacc cccugcugga aacuacacac aucaccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccgcaccga ccgaggcugg     1080

uacugcgaua acgccggcag cgucuccuuc uucccccaag cagaaaccug caagguccaa     1140

uccaaccgag uuuucugcga cacuaugaac ucgcucaccc uccccuccga agucaaccuc     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

guauccuccu ccgucaucac cucccuaggc gccauaguaa guugcuacgg caaaaccaag     1320

ugcacagcaa gcaacaaaaa ccgaggaaua aucaaaaccu ucuccaacgg cugcgacuac     1380

guauccaaca agggcgucga caccguaucc guagggaaca cccuuuacug cguaaacaaa     1440

caagaaggac aaucacucua cguaaaaggc gaacccauaa ucaacuucua cgacccccuc     1500

guauuucccu ccgacgaauu ugacgcauca aucucacagg ucaacgaaaa aauaaaccaa     1560

ucgcuagcau ucaucagaaa aucagacgaa cuccuacaca acgucaacgc aggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgucauaa ucgucauacu acucucacuc     1680

auagcagucg gccuccuccu auacuguaaa gcaaggucga ccccagucac ccuauccaaa     1740

gaccaacuaa gcggcaucaa caacaucgcg uucucaaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  1669
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1669
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1670
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1670
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1671
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1671
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1672
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1672
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag accaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1673
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1673
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1674
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1674
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag accaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1675
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1675
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu aaaagcaaac gcuauaacaa caauacuaac agcagucaca      180

uucugcuuug caucaggcca aaacaucaca gaagaauuuu accaaucaac augcuccgcc      240

guaucgaaag gauaccuagg cgcauuaaga accggauggu auacaucagu cauaacaauu      300

gaacuaucua acauaaaaga aaacaaaugu aacggcacag augccaaagu aaaacucauc      360

aaacaagaau uagauaaaua caaaaacgca gucacugaac uacaacucuu aaugcaauca      420

acaccugcaa caggaucagg aucagcaaua ugcucaggag uagccguaug uaaaguacua      480

caccuagaag gagaagucaa caaaauaaaa ucagcccucc uaaguacaaa caaagcuguc      540

guaucacuau ccaauggugu uucaguacua acuuucaaag uucuagaccu aaaaaacuac      600

auagacaaac aacuacuacc aauacuaaau aaacaaaguu guucuauacc caacauagaa      660

accgucauag aauuucaaca aaaaaauaau agacuccuag aaauaacaag agaauuuuca      720

guuaacgcag guguaacaac cccaguaucc accuauaugc uaacaaauuc agaauuacuu      780

ucccuaauca acgacaugcc cauaacaaau gaccaaaaaa aauuaauguc aaacaacguc      840

caaauaguuc gucaacaauc auauucaaua augugcauaa uaaaagaaga agucuuagcc      900

uacguaguac aacuuccccu uuauggaguu aucgacacac ccugcuggaa acuccacacu      960

ucaccacuau guacuacaaa cacaaaagaa ggauccaaca ucugccucac aagaaccgau     1020

cgaggauggu acugugauaa cgccggaucc gucucauucu ucccacaagc agaaacaugc     1080

aaaguacaau caaacagagu auuuugcgac acaaugaacu cccucacauu accuucugaa     1140

guaaaccuau guaauguaga cauauucaac cccaaauacg auugcaaaau aaugacauca     1200

aagacagaug uaucaucaag ugucaucaca ucccuaggag caauugucuc auguuauggu     1260

aaaacaaaau gcaccgcauc aaauaaaaac agaggcauaa uaaaaaccuu cucaaacggu     1320

ugugacuacg uauccaauaa aggcgucgac acaguaucag uagguaacac auuauauugu     1380

guaaacaaac aagaaggaca gucccuauau guaaaaggag aaccaauaau caacuucuac     1440

gacccacuug uuuucccuuc ugaugaauuu gacgcaagua uaucacaagu aaaugaaaaa     1500

aucaaucaau cacuagccuu uauaagaaaa ucagaugaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa ucgucauaau agucauccua     1620

cuaucacuca uagcaguugg acuccuacua uacugcaaag cacgaucaac accaguaaca     1680

uuauccaaag accaacuaag ugguaucaau aacaucgccu uuucaaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1676
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1676
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauccu caaagccaac gcaaucacca caauccucac ugccgucacc      180

uucugcuucg ccuccggcca aaacauaaca gaagaauuuu accaaucaac cuguucagcg      240

gucuccaaag gcuaccucgg cgcccuccgc accggcuggu acaccuccgu gaucaccaua      300

gaacucucca acaucaagga aaacaaaugc aacggcaccg acgcgaaggu caaacuuauu      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uacaacuccu aaugcagucc      420

acgccagcca ccggcucugg cucagccaua ugcuccggug uggccguaug caaaguccua      480

caccucgaag gagaagucaa caaaauaaaa uccgcccuac uguccacaaa caaggccgua      540

gucucccucu caaacggcgu cucaguacuc accuucaaag uccuagaccu caagaacuac      600

aucgacaaac aacuccuacc cauacuaaac aaacaauccu gcucaauccc caacaucgaa      660

accguaauag aauuucaaca aaaaaacaac agacuccugg agaucacccg ggaauuuucc      720

guaaacgccg gagucacaac acccgucuca accuacaugc uaacgaacuc agagcuccuc      780

ucacuuauca acgacaugcc cauaacaaac gaccaaaaaa aacucauguc caacaacgug      840

caaaucgucc gacaacaauc cuacuccauc augugcauca uuaaagaaga aguccucgca      900

uacguagucc agcucccccu cuacggcguc auagacaccc ccugcuggaa acuacacaca      960

ucaccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgaggcuggu acugcgauaa cgccggcagc gucuccuucu ucccccaagc agaaaccugc     1080

aagguccaau ccaaccgagu uuucugcgac acuaugaacu cgcucacccu ccccuccgaa     1140

gucaaccucu gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucc     1200

aagaccgacg uauccuccuc cgucaucacc ucccuaggcg ccauaguaag uugcuacggc     1260

aaaaccaagu gcacagcaag caacaaaaac cgaggaauaa ucaaaaccuu cuccaacggc     1320

ugcgacuacg uauccaacaa gggcgucgac accguauccg uagggaacac ccuuuacugc     1380

guaaacaaac aagaaggaca aucacucuac guaaaaggcg aacccauaau caacuucuac     1440

gacccccucg uauuucccuc cgacgaauuu gacgcaucaa ucucacaggu caacgaaaaa     1500

auaaaccaau cgcuagcauu caucagaaaa ucagacgaac uccuacacaa cgucaacgca     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgucauaau cgucauacua     1620

cucucacuca uagcagucgg ccuccuccua uacuguaaag caaggucgac cccagucacc     1680

cuauccaaag accaacuaag cggcaucaac aacaucgcgu ucucaaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  1677
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1677
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1678
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1678
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1679
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1679
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1680
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1680
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagacca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1681
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1681
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1682
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1682
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagacca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1683
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1683
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuaaaa gcaaacgcua uaacaacaau acuaacagca      120

gucacauucu gcuuugcauc aggccaaaac aucacagaag aauuuuacca aucaacaugc      180

uccgccguau cgaaaggaua ccuaggcgca uuaagaaccg gaugguauac aucagucaua      240

acaauugaac uaucuaacau aaaagaaaac aaauguaacg gcacagaugc caaaguaaaa      300

cucaucaaac aagaauuaga uaaauacaaa aacgcaguca cugaacuaca acucuuaaug      360

caaucaacac cugcaacagg aucaggauca gcaauaugcu caggaguagc cguauguaaa      420

guacuacacc uagaaggaga agucaacaaa auaaaaucag cccuccuaag uacaaacaaa      480

gcugucguau cacuauccaa ugguguuuca guacuaacuu ucaaaguucu agaccuaaaa      540

aacuacauag acaaacaacu acuaccaaua cuaaauaaac aaaguuguuc uauacccaac      600

auagaaaccg ucauagaauu ucaacaaaaa aauaauagac uccuagaaau aacaagagaa      660

uuuucaguua acgcaggugu aacaacccca guauccaccu auaugcuaac aaauucagaa      720

uuacuuuccc uaaucaacga caugcccaua acaaaugacc aaaaaaaauu aaugucaaac      780

aacguccaaa uaguucguca acaaucauau ucaauaaugu gcauaauaaa agaagaaguc      840

uuagccuacg uaguacaacu uccccuuuau ggaguuaucg acacacccug cuggaaacuc      900

cacacuucac cacuauguac uacaaacaca aaagaaggau ccaacaucug ccucacaaga      960

accgaucgag gaugguacug ugauaacgcc ggauccgucu cauucuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa cagaguauuu ugcgacacaa ugaacucccu cacauuaccu     1080

ucugaaguaa accuauguaa uguagacaua uucaacccca aauacgauug caaaauaaug     1140

acaucaaaga cagauguauc aucaaguguc aucacauccc uaggagcaau ugucucaugu     1200

uaugguaaaa caaaaugcac cgcaucaaau aaaaacagag gcauaauaaa aaccuucuca     1260

aacgguugug acuacguauc caauaaaggc gucgacacag uaucaguagg uaacacauua     1320

uauuguguaa acaaacaaga aggacagucc cuauauguaa aaggagaacc aauaaucaac     1380

uucuacgacc cacuuguuuu cccuucugau gaauuugacg caaguauauc acaaguaaau     1440

gaaaaaauca aucaaucacu agccuuuaua agaaaaucag augaauuauu acacaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaaccacaa uaauaaucgu cauaauaguc     1560

auccuacuau cacucauagc aguuggacuc cuacuauacu gcaaagcacg aucaacacca     1620

guaacauuau ccaaagacca acuaaguggu aucaauaaca ucgccuuuuc aaacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1684
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1684
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauccucaaa gccaacgcaa ucaccacaau ccucacugcc      120

gucaccuucu gcuucgccuc cggccaaaac auaacagaag aauuuuacca aucaaccugu      180

ucagcggucu ccaaaggcua ccucggcgcc cuccgcaccg gcugguacac cuccgugauc      240

accauagaac ucuccaacau caaggaaaac aaaugcaacg gcaccgacgc gaaggucaaa      300

cuuauuaaac aagaacucga caaauacaaa aacgcaguca ccgaacuaca acuccuaaug      360

caguccacgc cagccaccgg cucuggcuca gccauaugcu ccgguguggc cguaugcaaa      420

guccuacacc ucgaaggaga agucaacaaa auaaaauccg cccuacuguc cacaaacaag      480

gccguagucu cccucucaaa cggcgucuca guacucaccu ucaaaguccu agaccucaag      540

aacuacaucg acaaacaacu ccuacccaua cuaaacaaac aauccugcuc aauccccaac      600

aucgaaaccg uaauagaauu ucaacaaaaa aacaacagac uccuggagau cacccgggaa      660

uuuuccguaa acgccggagu cacaacaccc gucucaaccu acaugcuaac gaacucagag      720

cuccucucac uuaucaacga caugcccaua acaaacgacc aaaaaaaacu cauguccaac      780

aacgugcaaa ucguccgaca acaauccuac uccaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg uaguccagcu cccccucuac ggcgucauag acacccccug cuggaaacua      900

cacacaucac cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgc      960

accgaccgag gcugguacug cgauaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accugcaagg uccaauccaa ccgaguuuuc ugcgacacua ugaacucgcu cacccucccc     1080

uccgaaguca accucugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accuccaaga ccgacguauc cuccuccguc aucaccuccc uaggcgccau aguaaguugc     1200

uacggcaaaa ccaagugcac agcaagcaac aaaaaccgag gaauaaucaa aaccuucucc     1260

aacggcugcg acuacguauc caacaagggc gucgacaccg uauccguagg gaacacccuu     1320

uacugcguaa acaaacaaga aggacaauca cucuacguaa aaggcgaacc cauaaucaac     1380

uucuacgacc cccucguauu ucccuccgac gaauuugacg caucaaucuc acaggucaac     1440

gaaaaaauaa accaaucgcu agcauucauc agaaaaucag acgaacuccu acacaacguc     1500

aacgcaggca agagcaccac caacaucaug aucaccacca ucaucaucgu cauaaucguc     1560

auacuacucu cacucauagc agucggccuc cuccuauacu guaaagcaag gucgacccca     1620

gucacccuau ccaaagacca acuaagcggc aucaacaaca ucgcguucuc aaacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  1685
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1685
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1800

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1686
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1686
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      660

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1500

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1560

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1800

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1687
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1687
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1800

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1688
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1688
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      600

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      660

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      720

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      840

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      900

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      960

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua     1020

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc     1080

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg     1140

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1200

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1260

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1320

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1380

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1440

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1500

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1560

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1620

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1680

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1740

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1800

aaagaccaac ucucugggau aaacaauauc gcauucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1689
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1689
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1800

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1690
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1690
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      600

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      660

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      720

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      840

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      900

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      960

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug     1020

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc     1080

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc     1140

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1200

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1260

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1320

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1380

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1440

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1500

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1560

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1620

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1740

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1800

aaagaccaac ucuccggaau uaacaauauc gcuuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1691
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1691
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac uaacagcagu cacauucugc      300

uuugcaucag gccaaaacau cacagaagaa uuuuaccaau caacaugcuc cgccguaucg      360

aaaggauacc uaggcgcauu aagaaccgga ugguauacau cagucauaac aauugaacua      420

ucuaacauaa aagaaaacaa auguaacggc acagaugcca aaguaaaacu caucaaacaa      480

gaauuagaua aauacaaaaa cgcagucacu gaacuacaac ucuuaaugca aucaacaccu      540

gcaacaggau caggaucagc aauaugcuca ggaguagccg uauguaaagu acuacaccua      600

gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua caaacaaagc ugucguauca      660

cuauccaaug guguuucagu acuaacuuuc aaaguucuag accuaaaaaa cuacauagac      720

aaacaacuac uaccaauacu aaauaaacaa aguuguucua uacccaacau agaaaccguc      780

auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa caagagaauu uucaguuaac      840

gcagguguaa caaccccagu auccaccuau augcuaacaa auucagaauu acuuucccua      900

aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa ugucaaacaa cguccaaaua      960

guucgucaac aaucauauuc aauaaugugc auaauaaaag aagaagucuu agccuacgua     1020

guacaacuuc cccuuuaugg aguuaucgac acacccugcu ggaaacucca cacuucacca     1080

cuauguacua caaacacaaa agaaggaucc aacaucugcc ucacaagaac cgaucgagga     1140

ugguacugug auaacgccgg auccgucuca uucuucccac aagcagaaac augcaaagua     1200

caaucaaaca gaguauuuug cgacacaaug aacucccuca cauuaccuuc ugaaguaaac     1260

cuauguaaug uagacauauu caaccccaaa uacgauugca aaauaaugac aucaaagaca     1320

gauguaucau caagugucau cacaucccua ggagcaauug ucucauguua ugguaaaaca     1380

aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa ccuucucaaa cgguugugac     1440

uacguaucca auaaaggcgu cgacacagua ucaguaggua acacauuaua uuguguaaac     1500

aaacaagaag gacagucccu auauguaaaa ggagaaccaa uaaucaacuu cuacgaccca     1560

cuuguuuucc cuucugauga auuugacgca aguauaucac aaguaaauga aaaaaucaau     1620

caaucacuag ccuuuauaag aaaaucagau gaauuauuac acaacguaaa cgccggaaaa     1680

ucaacaacca acauaaugau aaccacaaua auaaucguca uaauagucau ccuacuauca     1740

cucauagcag uuggacuccu acuauacugc aaagcacgau caacaccagu aacauuaucc     1800

aaagaccaac uaagugguau caauaacauc gccuuuucaa acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1692
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1692
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuaa uccucaaagc caacgcaauc accacaaucc ucacugccgu caccuucugc      300

uucgccuccg gccaaaacau aacagaagaa uuuuaccaau caaccuguuc agcggucucc      360

aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgugaucac cauagaacuc      420

uccaacauca aggaaaacaa augcaacggc accgacgcga aggucaaacu uauuaaacaa      480

gaacucgaca aauacaaaaa cgcagucacc gaacuacaac uccuaaugca guccacgcca      540

gccaccggcu cuggcucagc cauaugcucc gguguggccg uaugcaaagu ccuacaccuc      600

gaaggagaag ucaacaaaau aaaauccgcc cuacugucca caaacaaggc cguagucucc      660

cucucaaacg gcgucucagu acucaccuuc aaaguccuag accucaagaa cuacaucgac      720

aaacaacucc uacccauacu aaacaaacaa uccugcucaa uccccaacau cgaaaccgua      780

auagaauuuc aacaaaaaaa caacagacuc cuggagauca cccgggaauu uuccguaaac      840

gccggaguca caacacccgu cucaaccuac augcuaacga acucagagcu ccucucacuu      900

aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca uguccaacaa cgugcaaauc      960

guccgacaac aauccuacuc caucaugugc aucauuaaag aagaaguccu cgcauacgua     1020

guccagcucc cccucuacgg cgucauagac acccccugcu ggaaacuaca cacaucaccc     1080

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccgcac cgaccgaggc     1140

ugguacugcg auaacgccgg cagcgucucc uucuuccccc aagcagaaac cugcaagguc     1200

caauccaacc gaguuuucug cgacacuaug aacucgcuca cccuccccuc cgaagucaac     1260

cucugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cuccaagacc     1320

gacguauccu ccuccgucau caccucccua ggcgccauag uaaguugcua cggcaaaacc     1380

aagugcacag caagcaacaa aaaccgagga auaaucaaaa ccuucuccaa cggcugcgac     1440

uacguaucca acaagggcgu cgacaccgua uccguaggga acacccuuua cugcguaaac     1500

aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca uaaucaacuu cuacgacccc     1560

cucguauuuc ccuccgacga auuugacgca ucaaucucac aggucaacga aaaaauaaac     1620

caaucgcuag cauucaucag aaaaucagac gaacuccuac acaacgucaa cgcaggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguca uaaucgucau acuacucuca     1740

cucauagcag ucggccuccu ccuauacugu aaagcaaggu cgaccccagu cacccuaucc     1800

aaagaccaac uaagcggcau caacaacauc gcguucucaa acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1693
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1693
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1694
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1694
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1620

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1695
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1695
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1696
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1696
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      720

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg      960

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1020

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1080

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1140

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1380

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1440

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1620

aaagaccaac ucucugggau aaacaauauc gcauucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1697
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1697
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1698
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1698
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      720

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc      960

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1080

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1140

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1380

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1440

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1620

aaagaccaac ucuccggaau uaacaauauc gcuuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1699
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1699
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac uaacagcagu cacauucugc      120

uuugcaucag gccaaaacau cacagaagaa uuuuaccaau caacaugcuc cgccguaucg      180

aaaggauacc uaggcgcauu aagaaccgga ugguauacau cagucauaac aauugaacua      240

ucuaacauaa aagaaaacaa auguaacggc acagaugcca aaguaaaacu caucaaacaa      300

gaauuagaua aauacaaaaa cgcagucacu gaacuacaac ucuuaaugca aucaacaccu      360

gcaacaggau caggaucagc aauaugcuca ggaguagccg uauguaaagu acuacaccua      420

gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua caaacaaagc ugucguauca      480

cuauccaaug guguuucagu acuaacuuuc aaaguucuag accuaaaaaa cuacauagac      540

aaacaacuac uaccaauacu aaauaaacaa aguuguucua uacccaacau agaaaccguc      600

auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa caagagaauu uucaguuaac      660

gcagguguaa caaccccagu auccaccuau augcuaacaa auucagaauu acuuucccua      720

aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa ugucaaacaa cguccaaaua      780

guucgucaac aaucauauuc aauaaugugc auaauaaaag aagaagucuu agccuacgua      840

guacaacuuc cccuuuaugg aguuaucgac acacccugcu ggaaacucca cacuucacca      900

cuauguacua caaacacaaa agaaggaucc aacaucugcc ucacaagaac cgaucgagga      960

ugguacugug auaacgccgg auccgucuca uucuucccac aagcagaaac augcaaagua     1020

caaucaaaca gaguauuuug cgacacaaug aacucccuca cauuaccuuc ugaaguaaac     1080

cuauguaaug uagacauauu caaccccaaa uacgauugca aaauaaugac aucaaagaca     1140

gauguaucau caagugucau cacaucccua ggagcaauug ucucauguua ugguaaaaca     1200

aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa ccuucucaaa cgguugugac     1260

uacguaucca auaaaggcgu cgacacagua ucaguaggua acacauuaua uuguguaaac     1320

aaacaagaag gacagucccu auauguaaaa ggagaaccaa uaaucaacuu cuacgaccca     1380

cuuguuuucc cuucugauga auuugacgca aguauaucac aaguaaauga aaaaaucaau     1440

caaucacuag ccuuuauaag aaaaucagau gaauuauuac acaacguaaa cgccggaaaa     1500

ucaacaacca acauaaugau aaccacaaua auaaucguca uaauagucau ccuacuauca     1560

cucauagcag uuggacuccu acuauacugc aaagcacgau caacaccagu aacauuaucc     1620

aaagaccaac uaagugguau caauaacauc gccuuuucaa acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1700
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1700
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuaa uccucaaagc caacgcaauc accacaaucc ucacugccgu caccuucugc      120

uucgccuccg gccaaaacau aacagaagaa uuuuaccaau caaccuguuc agcggucucc      180

aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgugaucac cauagaacuc      240

uccaacauca aggaaaacaa augcaacggc accgacgcga aggucaaacu uauuaaacaa      300

gaacucgaca aauacaaaaa cgcagucacc gaacuacaac uccuaaugca guccacgcca      360

gccaccggcu cuggcucagc cauaugcucc gguguggccg uaugcaaagu ccuacaccuc      420

gaaggagaag ucaacaaaau aaaauccgcc cuacugucca caaacaaggc cguagucucc      480

cucucaaacg gcgucucagu acucaccuuc aaaguccuag accucaagaa cuacaucgac      540

aaacaacucc uacccauacu aaacaaacaa uccugcucaa uccccaacau cgaaaccgua      600

auagaauuuc aacaaaaaaa caacagacuc cuggagauca cccgggaauu uuccguaaac      660

gccggaguca caacacccgu cucaaccuac augcuaacga acucagagcu ccucucacuu      720

aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca uguccaacaa cgugcaaauc      780

guccgacaac aauccuacuc caucaugugc aucauuaaag aagaaguccu cgcauacgua      840

guccagcucc cccucuacgg cgucauagac acccccugcu ggaaacuaca cacaucaccc      900

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccgcac cgaccgaggc      960

ugguacugcg auaacgccgg cagcgucucc uucuuccccc aagcagaaac cugcaagguc     1020

caauccaacc gaguuuucug cgacacuaug aacucgcuca cccuccccuc cgaagucaac     1080

cucugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cuccaagacc     1140

gacguauccu ccuccgucau caccucccua ggcgccauag uaaguugcua cggcaaaacc     1200

aagugcacag caagcaacaa aaaccgagga auaaucaaaa ccuucuccaa cggcugcgac     1260

uacguaucca acaagggcgu cgacaccgua uccguaggga acacccuuua cugcguaaac     1320

aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca uaaucaacuu cuacgacccc     1380

cucguauuuc ccuccgacga auuugacgca ucaaucucac aggucaacga aaaaauaaac     1440

caaucgcuag cauucaucag aaaaucagac gaacuccuac acaacgucaa cgcaggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguca uaaucgucau acuacucuca     1560

cucauagcag ucggccuccu ccuauacugu aaagcaaggu cgaccccagu cacccuaucc     1620

aaagaccaac uaagcggcau caacaacauc gcguucucaa acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  1701
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1701
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1702
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1702
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1703
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1703
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1704
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1704
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaccaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1705
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1705
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1706
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1706
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaccaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1707
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1707
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac      120

uaacagcagu cacauucugc uuugcaucag gccaaaacau cacagaagaa uuuuaccaau      180

caacaugcuc cgccguaucg aaaggauacc uaggcgcauu aagaaccgga ugguauacau      240

cagucauaac aauugaacua ucuaacauaa aagaaaacaa auguaacggc acagaugcca      300

aaguaaaacu caucaaacaa gaauuagaua aauacaaaaa cgcagucacu gaacuacaac      360

ucuuaaugca aucaacaccu gcaacaggau caggaucagc aauaugcuca ggaguagccg      420

uauguaaagu acuacaccua gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua      480

caaacaaagc ugucguauca cuauccaaug guguuucagu acuaacuuuc aaaguucuag      540

accuaaaaaa cuacauagac aaacaacuac uaccaauacu aaauaaacaa aguuguucua      600

uacccaacau agaaaccguc auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa      660

caagagaauu uucaguuaac gcagguguaa caaccccagu auccaccuau augcuaacaa      720

auucagaauu acuuucccua aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa      780

ugucaaacaa cguccaaaua guucgucaac aaucauauuc aauaaugugc auaauaaaag      840

aagaagucuu agccuacgua guacaacuuc cccuuuaugg aguuaucgac acacccugcu      900

ggaaacucca cacuucacca cuauguacua caaacacaaa agaaggaucc aacaucugcc      960

ucacaagaac cgaucgagga ugguacugug auaacgccgg auccgucuca uucuucccac     1020

aagcagaaac augcaaagua caaucaaaca gaguauuuug cgacacaaug aacucccuca     1080

cauuaccuuc ugaaguaaac cuauguaaug uagacauauu caaccccaaa uacgauugca     1140

aaauaaugac aucaaagaca gauguaucau caagugucau cacaucccua ggagcaauug     1200

ucucauguua ugguaaaaca aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa     1260

ccuucucaaa cgguugugac uacguaucca auaaaggcgu cgacacagua ucaguaggua     1320

acacauuaua uuguguaaac aaacaagaag gacagucccu auauguaaaa ggagaaccaa     1380

uaaucaacuu cuacgaccca cuuguuuucc cuucugauga auuugacgca aguauaucac     1440

aaguaaauga aaaaaucaau caaucacuag ccuuuauaag aaaaucagau gaauuauuac     1500

acaacguaaa cgccggaaaa ucaacaacca acauaaugau aaccacaaua auaaucguca     1560

uaauagucau ccuacuauca cucauagcag uuggacuccu acuauacugc aaagcacgau     1620

caacaccagu aacauuaucc aaagaccaac uaagugguau caauaacauc gccuuuucaa     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1708
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1708
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uccucaaagc caacgcaauc accacaaucc      120

ucacugccgu caccuucugc uucgccuccg gccaaaacau aacagaagaa uuuuaccaau      180

caaccuguuc agcggucucc aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgugaucac cauagaacuc uccaacauca aggaaaacaa augcaacggc accgacgcga      300

aggucaaacu uauuaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuacaac      360

uccuaaugca guccacgcca gccaccggcu cuggcucagc cauaugcucc gguguggccg      420

uaugcaaagu ccuacaccuc gaaggagaag ucaacaaaau aaaauccgcc cuacugucca      480

caaacaaggc cguagucucc cucucaaacg gcgucucagu acucaccuuc aaaguccuag      540

accucaagaa cuacaucgac aaacaacucc uacccauacu aaacaaacaa uccugcucaa      600

uccccaacau cgaaaccgua auagaauuuc aacaaaaaaa caacagacuc cuggagauca      660

cccgggaauu uuccguaaac gccggaguca caacacccgu cucaaccuac augcuaacga      720

acucagagcu ccucucacuu aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

uguccaacaa cgugcaaauc guccgacaac aauccuacuc caucaugugc aucauuaaag      840

aagaaguccu cgcauacgua guccagcucc cccucuacgg cgucauagac acccccugcu      900

ggaaacuaca cacaucaccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccgcac cgaccgaggc ugguacugcg auaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cugcaagguc caauccaacc gaguuuucug cgacacuaug aacucgcuca     1080

cccuccccuc cgaagucaac cucugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cuccaagacc gacguauccu ccuccgucau caccucccua ggcgccauag     1200

uaaguugcua cggcaaaacc aagugcacag caagcaacaa aaaccgagga auaaucaaaa     1260

ccuucuccaa cggcugcgac uacguaucca acaagggcgu cgacaccgua uccguaggga     1320

acacccuuua cugcguaaac aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca     1380

uaaucaacuu cuacgacccc cucguauuuc ccuccgacga auuugacgca ucaaucucac     1440

aggucaacga aaaaauaaac caaucgcuag cauucaucag aaaaucagac gaacuccuac     1500

acaacgucaa cgcaggcaag agcaccacca acaucaugau caccaccauc aucaucguca     1560

uaaucgucau acuacucuca cucauagcag ucggccuccu ccuauacugu aaagcaaggu     1620

cgaccccagu cacccuaucc aaagaccaac uaagcggcau caacaacauc gcguucucaa     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1709
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1709
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1710
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1710
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1711
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1711
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1712
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1712
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaccaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1713
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1713
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1714
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1714
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaccaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1715
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1715
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac      120

uaacagcagu cacauucugc uuugcaucag gccaaaacau cacagaagaa uuuuaccaau      180

caacaugcuc cgccguaucg aaaggauacc uaggcgcauu aagaaccgga ugguauacau      240

cagucauaac aauugaacua ucuaacauaa aagaaaacaa auguaacggc acagaugcca      300

aaguaaaacu caucaaacaa gaauuagaua aauacaaaaa cgcagucacu gaacuacaac      360

ucuuaaugca aucaacaccu gcaacaggau caggaucagc aauaugcuca ggaguagccg      420

uauguaaagu acuacaccua gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua      480

caaacaaagc ugucguauca cuauccaaug guguuucagu acuaacuuuc aaaguucuag      540

accuaaaaaa cuacauagac aaacaacuac uaccaauacu aaauaaacaa aguuguucua      600

uacccaacau agaaaccguc auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa      660

caagagaauu uucaguuaac gcagguguaa caaccccagu auccaccuau augcuaacaa      720

auucagaauu acuuucccua aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa      780

ugucaaacaa cguccaaaua guucgucaac aaucauauuc aauaaugugc auaauaaaag      840

aagaagucuu agccuacgua guacaacuuc cccuuuaugg aguuaucgac acacccugcu      900

ggaaacucca cacuucacca cuauguacua caaacacaaa agaaggaucc aacaucugcc      960

ucacaagaac cgaucgagga ugguacugug auaacgccgg auccgucuca uucuucccac     1020

aagcagaaac augcaaagua caaucaaaca gaguauuuug cgacacaaug aacucccuca     1080

cauuaccuuc ugaaguaaac cuauguaaug uagacauauu caaccccaaa uacgauugca     1140

aaauaaugac aucaaagaca gauguaucau caagugucau cacaucccua ggagcaauug     1200

ucucauguua ugguaaaaca aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa     1260

ccuucucaaa cgguugugac uacguaucca auaaaggcgu cgacacagua ucaguaggua     1320

acacauuaua uuguguaaac aaacaagaag gacagucccu auauguaaaa ggagaaccaa     1380

uaaucaacuu cuacgaccca cuuguuuucc cuucugauga auuugacgca aguauaucac     1440

aaguaaauga aaaaaucaau caaucacuag ccuuuauaag aaaaucagau gaauuauuac     1500

acaacguaaa cgccggaaaa ucaacaacca acauaaugau aaccacaaua auaaucguca     1560

uaauagucau ccuacuauca cucauagcag uuggacuccu acuauacugc aaagcacgau     1620

caacaccagu aacauuaucc aaagaccaac uaagugguau caauaacauc gccuuuucaa     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1716
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1716
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uccucaaagc caacgcaauc accacaaucc      120

ucacugccgu caccuucugc uucgccuccg gccaaaacau aacagaagaa uuuuaccaau      180

caaccuguuc agcggucucc aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgugaucac cauagaacuc uccaacauca aggaaaacaa augcaacggc accgacgcga      300

aggucaaacu uauuaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuacaac      360

uccuaaugca guccacgcca gccaccggcu cuggcucagc cauaugcucc gguguggccg      420

uaugcaaagu ccuacaccuc gaaggagaag ucaacaaaau aaaauccgcc cuacugucca      480

caaacaaggc cguagucucc cucucaaacg gcgucucagu acucaccuuc aaaguccuag      540

accucaagaa cuacaucgac aaacaacucc uacccauacu aaacaaacaa uccugcucaa      600

uccccaacau cgaaaccgua auagaauuuc aacaaaaaaa caacagacuc cuggagauca      660

cccgggaauu uuccguaaac gccggaguca caacacccgu cucaaccuac augcuaacga      720

acucagagcu ccucucacuu aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

uguccaacaa cgugcaaauc guccgacaac aauccuacuc caucaugugc aucauuaaag      840

aagaaguccu cgcauacgua guccagcucc cccucuacgg cgucauagac acccccugcu      900

ggaaacuaca cacaucaccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccgcac cgaccgaggc ugguacugcg auaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cugcaagguc caauccaacc gaguuuucug cgacacuaug aacucgcuca     1080

cccuccccuc cgaagucaac cucugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cuccaagacc gacguauccu ccuccgucau caccucccua ggcgccauag     1200

uaaguugcua cggcaaaacc aagugcacag caagcaacaa aaaccgagga auaaucaaaa     1260

ccuucuccaa cggcugcgac uacguaucca acaagggcgu cgacaccgua uccguaggga     1320

acacccuuua cugcguaaac aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca     1380

uaaucaacuu cuacgacccc cucguauuuc ccuccgacga auuugacgca ucaaucucac     1440

aggucaacga aaaaauaaac caaucgcuag cauucaucag aaaaucagac gaacuccuac     1500

acaacgucaa cgcaggcaag agcaccacca acaucaugau caccaccauc aucaucguca     1560

uaaucgucau acuacucuca cucauagcag ucggccuccu ccuauacugu aaagcaaggu     1620

cgaccccagu cacccuaucc aaagaccaac uaagcggcau caacaacauc gcguucucaa     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  1717
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1717
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1718
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1718
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1719
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1719
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1720
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1720
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag accaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1721
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1721
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1722
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1722
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag accaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1723
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1723
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu aaaagcaaac gcuauaacaa caauacuaac agcagucaca      180

uucugcuuug caucaggcca aaacaucaca gaagaauuuu accaaucaac augcuccgcc      240

guaucgaaag gauaccuagg cgcauuaaga accggauggu auacaucagu cauaacaauu      300

gaacuaucua acauaaaaga aaacaaaugu aacggcacag augccaaagu aaaacucauc      360

aaacaagaau uagauaaaua caaaaacgca gucacugaac uacaacucuu aaugcaauca      420

acaccugcaa caggaucagg aucagcaaua ugcucaggag uagccguaug uaaaguacua      480

caccuagaag gagaagucaa caaaauaaaa ucagcccucc uaaguacaaa caaagcuguc      540

guaucacuau ccaauggugu uucaguacua acuuucaaag uucuagaccu aaaaaacuac      600

auagacaaac aacuacuacc aauacuaaau aaacaaaguu guucuauacc caacauagaa      660

accgucauag aauuucaaca aaaaaauaau agacuccuag aaauaacaag agaauuuuca      720

guuaacgcag guguaacaac cccaguaucc accuauaugc uaacaaauuc agaauuacuu      780

ucccuaauca acgacaugcc cauaacaaau gaccaaaaaa aauuaauguc aaacaacguc      840

caaauaguuc gucaacaauc auauucaaua augugcauaa uaaaagaaga agucuuagcc      900

uacguaguac aacuuccccu uuauggaguu aucgacacac ccugcuggaa acuccacacu      960

ucaccacuau guacuacaaa cacaaaagaa ggauccaaca ucugccucac aagaaccgau     1020

cgaggauggu acugugauaa cgccggaucc gucucauucu ucccacaagc agaaacaugc     1080

aaaguacaau caaacagagu auuuugcgac acaaugaacu cccucacauu accuucugaa     1140

guaaaccuau guaauguaga cauauucaac cccaaauacg auugcaaaau aaugacauca     1200

aagacagaug uaucaucaag ugucaucaca ucccuaggag caauugucuc auguuauggu     1260

aaaacaaaau gcaccgcauc aaauaaaaac agaggcauaa uaaaaaccuu cucaaacggu     1320

ugugacuacg uauccaauaa aggcgucgac acaguaucag uagguaacac auuauauugu     1380

guaaacaaac aagaaggaca gucccuauau guaaaaggag aaccaauaau caacuucuac     1440

gacccacuug uuuucccuuc ugaugaauuu gacgcaagua uaucacaagu aaaugaaaaa     1500

aucaaucaau cacuagccuu uauaagaaaa ucagaugaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa ucgucauaau agucauccua     1620

cuaucacuca uagcaguugg acuccuacua uacugcaaag cacgaucaac accaguaaca     1680

uuauccaaag accaacuaag ugguaucaau aacaucgccu uuucaaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1724
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1724
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauccu caaagccaac gcaaucacca caauccucac ugccgucacc      180

uucugcuucg ccuccggcca aaacauaaca gaagaauuuu accaaucaac cuguucagcg      240

gucuccaaag gcuaccucgg cgcccuccgc accggcuggu acaccuccgu gaucaccaua      300

gaacucucca acaucaagga aaacaaaugc aacggcaccg acgcgaaggu caaacuuauu      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uacaacuccu aaugcagucc      420

acgccagcca ccggcucugg cucagccaua ugcuccggug uggccguaug caaaguccua      480

caccucgaag gagaagucaa caaaauaaaa uccgcccuac uguccacaaa caaggccgua      540

gucucccucu caaacggcgu cucaguacuc accuucaaag uccuagaccu caagaacuac      600

aucgacaaac aacuccuacc cauacuaaac aaacaauccu gcucaauccc caacaucgaa      660

accguaauag aauuucaaca aaaaaacaac agacuccugg agaucacccg ggaauuuucc      720

guaaacgccg gagucacaac acccgucuca accuacaugc uaacgaacuc agagcuccuc      780

ucacuuauca acgacaugcc cauaacaaac gaccaaaaaa aacucauguc caacaacgug      840

caaaucgucc gacaacaauc cuacuccauc augugcauca uuaaagaaga aguccucgca      900

uacguagucc agcucccccu cuacggcguc auagacaccc ccugcuggaa acuacacaca      960

ucaccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgaggcuggu acugcgauaa cgccggcagc gucuccuucu ucccccaagc agaaaccugc     1080

aagguccaau ccaaccgagu uuucugcgac acuaugaacu cgcucacccu ccccuccgaa     1140

gucaaccucu gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucc     1200

aagaccgacg uauccuccuc cgucaucacc ucccuaggcg ccauaguaag uugcuacggc     1260

aaaaccaagu gcacagcaag caacaaaaac cgaggaauaa ucaaaaccuu cuccaacggc     1320

ugcgacuacg uauccaacaa gggcgucgac accguauccg uagggaacac ccuuuacugc     1380

guaaacaaac aagaaggaca aucacucuac guaaaaggcg aacccauaau caacuucuac     1440

gacccccucg uauuucccuc cgacgaauuu gacgcaucaa ucucacaggu caacgaaaaa     1500

auaaaccaau cgcuagcauu caucagaaaa ucagacgaac uccuacacaa cgucaacgca     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgucauaau cgucauacua     1620

cucucacuca uagcagucgg ccuccuccua uacuguaaag caaggucgac cccagucacc     1680

cuauccaaag accaacuaag cggcaucaac aacaucgcgu ucucaaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  1725
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1725
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1726
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1726
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1727
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1727
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1728
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1728
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaccaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1729
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1729
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1730
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1730
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaccaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1731
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1731
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuaaaagca      120

aacgcuauaa caacaauacu aacagcaguc acauucugcu uugcaucagg ccaaaacauc      180

acagaagaau uuuaccaauc aacaugcucc gccguaucga aaggauaccu aggcgcauua      240

agaaccggau gguauacauc agucauaaca auugaacuau cuaacauaaa agaaaacaaa      300

uguaacggca cagaugccaa aguaaaacuc aucaaacaag aauuagauaa auacaaaaac      360

gcagucacug aacuacaacu cuuaaugcaa ucaacaccug caacaggauc aggaucagca      420

auaugcucag gaguagccgu auguaaagua cuacaccuag aaggagaagu caacaaaaua      480

aaaucagccc uccuaaguac aaacaaagcu gucguaucac uauccaaugg uguuucagua      540

cuaacuuuca aaguucuaga ccuaaaaaac uacauagaca aacaacuacu accaauacua      600

aauaaacaaa guuguucuau acccaacaua gaaaccguca uagaauuuca acaaaaaaau      660

aauagacucc uagaaauaac aagagaauuu ucaguuaacg cagguguaac aaccccagua      720

uccaccuaua ugcuaacaaa uucagaauua cuuucccuaa ucaacgacau gcccauaaca      780

aaugaccaaa aaaaauuaau gucaaacaac guccaaauag uucgucaaca aucauauuca      840

auaaugugca uaauaaaaga agaagucuua gccuacguag uacaacuucc ccuuuaugga      900

guuaucgaca cacccugcug gaaacuccac acuucaccac uauguacuac aaacacaaaa      960

gaaggaucca acaucugccu cacaagaacc gaucgaggau gguacuguga uaacgccgga     1020

uccgucucau ucuucccaca agcagaaaca ugcaaaguac aaucaaacag aguauuuugc     1080

gacacaauga acucccucac auuaccuucu gaaguaaacc uauguaaugu agacauauuc     1140

aaccccaaau acgauugcaa aauaaugaca ucaaagacag auguaucauc aagugucauc     1200

acaucccuag gagcaauugu cucauguuau gguaaaacaa aaugcaccgc aucaaauaaa     1260

aacagaggca uaauaaaaac cuucucaaac gguugugacu acguauccaa uaaaggcguc     1320

gacacaguau caguagguaa cacauuauau uguguaaaca aacaagaagg acagucccua     1380

uauguaaaag gagaaccaau aaucaacuuc uacgacccac uuguuuuccc uucugaugaa     1440

uuugacgcaa guauaucaca aguaaaugaa aaaaucaauc aaucacuagc cuuuauaaga     1500

aaaucagaug aauuauuaca caacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaaucgucau aauagucauc cuacuaucac ucauagcagu uggacuccua     1620

cuauacugca aagcacgauc aacaccagua acauuaucca aagaccaacu aagugguauc     1680

aauaacaucg ccuuuucaaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1732
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1732
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau ccucaaagcc      120

aacgcaauca ccacaauccu cacugccguc accuucugcu ucgccuccgg ccaaaacaua      180

acagaagaau uuuaccaauc aaccuguuca gcggucucca aaggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgugaucacc auagaacucu ccaacaucaa ggaaaacaaa      300

ugcaacggca ccgacgcgaa ggucaaacuu auuaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuacaacu ccuaaugcag uccacgccag ccaccggcuc uggcucagcc      420

auaugcuccg guguggccgu augcaaaguc cuacaccucg aaggagaagu caacaaaaua      480

aaauccgccc uacuguccac aaacaaggcc guagucuccc ucucaaacgg cgucucagua      540

cucaccuuca aaguccuaga ccucaagaac uacaucgaca aacaacuccu acccauacua      600

aacaaacaau ccugcucaau ccccaacauc gaaaccguaa uagaauuuca acaaaaaaac      660

aacagacucc uggagaucac ccgggaauuu uccguaaacg ccggagucac aacacccguc      720

ucaaccuaca ugcuaacgaa cucagagcuc cucucacuua ucaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau guccaacaac gugcaaaucg uccgacaaca auccuacucc      840

aucaugugca ucauuaaaga agaaguccuc gcauacguag uccagcuccc ccucuacggc      900

gucauagaca cccccugcug gaaacuacac acaucacccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccgcacc gaccgaggcu gguacugcga uaacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc ugcaaggucc aauccaaccg aguuuucugc     1080

gacacuauga acucgcucac ccuccccucc gaagucaacc ucugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acguauccuc cuccgucauc     1200

accucccuag gcgccauagu aaguugcuac ggcaaaacca agugcacagc aagcaacaaa     1260

aaccgaggaa uaaucaaaac cuucuccaac ggcugcgacu acguauccaa caagggcguc     1320

gacaccguau ccguagggaa cacccuuuac ugcguaaaca aacaagaagg acaaucacuc     1380

uacguaaaag gcgaacccau aaucaacuuc uacgaccccc ucguauuucc cuccgacgaa     1440

uuugacgcau caaucucaca ggucaacgaa aaaauaaacc aaucgcuagc auucaucaga     1500

aaaucagacg aacuccuaca caacgucaac gcaggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgucau aaucgucaua cuacucucac ucauagcagu cggccuccuc     1620

cuauacugua aagcaagguc gaccccaguc acccuaucca aagaccaacu aagcggcauc     1680

aacaacaucg cguucucaaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  1733
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1733
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1734
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1734
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1735
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1735
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1736
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1736
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag accaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1737
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1737
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1738
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1738
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag accaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1739
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1739
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu aaaagcaaac gcuauaacaa caauacuaac agcagucaca      180

uucugcuuug caucaggcca aaacaucaca gaagaauuuu accaaucaac augcuccgcc      240

guaucgaaag gauaccuagg cgcauuaaga accggauggu auacaucagu cauaacaauu      300

gaacuaucua acauaaaaga aaacaaaugu aacggcacag augccaaagu aaaacucauc      360

aaacaagaau uagauaaaua caaaaacgca gucacugaac uacaacucuu aaugcaauca      420

acaccugcaa caggaucagg aucagcaaua ugcucaggag uagccguaug uaaaguacua      480

caccuagaag gagaagucaa caaaauaaaa ucagcccucc uaaguacaaa caaagcuguc      540

guaucacuau ccaauggugu uucaguacua acuuucaaag uucuagaccu aaaaaacuac      600

auagacaaac aacuacuacc aauacuaaau aaacaaaguu guucuauacc caacauagaa      660

accgucauag aauuucaaca aaaaaauaau agacuccuag aaauaacaag agaauuuuca      720

guuaacgcag guguaacaac cccaguaucc accuauaugc uaacaaauuc agaauuacuu      780

ucccuaauca acgacaugcc cauaacaaau gaccaaaaaa aauuaauguc aaacaacguc      840

caaauaguuc gucaacaauc auauucaaua augugcauaa uaaaagaaga agucuuagcc      900

uacguaguac aacuuccccu uuauggaguu aucgacacac ccugcuggaa acuccacacu      960

ucaccacuau guacuacaaa cacaaaagaa ggauccaaca ucugccucac aagaaccgau     1020

cgaggauggu acugugauaa cgccggaucc gucucauucu ucccacaagc agaaacaugc     1080

aaaguacaau caaacagagu auuuugcgac acaaugaacu cccucacauu accuucugaa     1140

guaaaccuau guaauguaga cauauucaac cccaaauacg auugcaaaau aaugacauca     1200

aagacagaug uaucaucaag ugucaucaca ucccuaggag caauugucuc auguuauggu     1260

aaaacaaaau gcaccgcauc aaauaaaaac agaggcauaa uaaaaaccuu cucaaacggu     1320

ugugacuacg uauccaauaa aggcgucgac acaguaucag uagguaacac auuauauugu     1380

guaaacaaac aagaaggaca gucccuauau guaaaaggag aaccaauaau caacuucuac     1440

gacccacuug uuuucccuuc ugaugaauuu gacgcaagua uaucacaagu aaaugaaaaa     1500

aucaaucaau cacuagccuu uauaagaaaa ucagaugaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa ucgucauaau agucauccua     1620

cuaucacuca uagcaguugg acuccuacua uacugcaaag cacgaucaac accaguaaca     1680

uuauccaaag accaacuaag ugguaucaau aacaucgccu uuucaaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1740
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1740
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauccu caaagccaac gcaaucacca caauccucac ugccgucacc      180

uucugcuucg ccuccggcca aaacauaaca gaagaauuuu accaaucaac cuguucagcg      240

gucuccaaag gcuaccucgg cgcccuccgc accggcuggu acaccuccgu gaucaccaua      300

gaacucucca acaucaagga aaacaaaugc aacggcaccg acgcgaaggu caaacuuauu      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uacaacuccu aaugcagucc      420

acgccagcca ccggcucugg cucagccaua ugcuccggug uggccguaug caaaguccua      480

caccucgaag gagaagucaa caaaauaaaa uccgcccuac uguccacaaa caaggccgua      540

gucucccucu caaacggcgu cucaguacuc accuucaaag uccuagaccu caagaacuac      600

aucgacaaac aacuccuacc cauacuaaac aaacaauccu gcucaauccc caacaucgaa      660

accguaauag aauuucaaca aaaaaacaac agacuccugg agaucacccg ggaauuuucc      720

guaaacgccg gagucacaac acccgucuca accuacaugc uaacgaacuc agagcuccuc      780

ucacuuauca acgacaugcc cauaacaaac gaccaaaaaa aacucauguc caacaacgug      840

caaaucgucc gacaacaauc cuacuccauc augugcauca uuaaagaaga aguccucgca      900

uacguagucc agcucccccu cuacggcguc auagacaccc ccugcuggaa acuacacaca      960

ucaccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgaggcuggu acugcgauaa cgccggcagc gucuccuucu ucccccaagc agaaaccugc     1080

aagguccaau ccaaccgagu uuucugcgac acuaugaacu cgcucacccu ccccuccgaa     1140

gucaaccucu gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucc     1200

aagaccgacg uauccuccuc cgucaucacc ucccuaggcg ccauaguaag uugcuacggc     1260

aaaaccaagu gcacagcaag caacaaaaac cgaggaauaa ucaaaaccuu cuccaacggc     1320

ugcgacuacg uauccaacaa gggcgucgac accguauccg uagggaacac ccuuuacugc     1380

guaaacaaac aagaaggaca aucacucuac guaaaaggcg aacccauaau caacuucuac     1440

gacccccucg uauuucccuc cgacgaauuu gacgcaucaa ucucacaggu caacgaaaaa     1500

auaaaccaau cgcuagcauu caucagaaaa ucagacgaac uccuacacaa cgucaacgca     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgucauaau cgucauacua     1620

cucucacuca uagcagucgg ccuccuccua uacuguaaag caaggucgac cccagucacc     1680

cuauccaaag accaacuaag cggcaucaac aacaucgcgu ucucaaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  1741
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1741
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1742
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1742
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1743
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1743
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1744
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1744
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaccaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1745
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1745
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1746
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1746
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaccaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1747
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1747
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuaaaagca      120

aacgcuauaa caacaauacu aacagcaguc acauucugcu uugcaucagg ccaaaacauc      180

acagaagaau uuuaccaauc aacaugcucc gccguaucga aaggauaccu aggcgcauua      240

agaaccggau gguauacauc agucauaaca auugaacuau cuaacauaaa agaaaacaaa      300

uguaacggca cagaugccaa aguaaaacuc aucaaacaag aauuagauaa auacaaaaac      360

gcagucacug aacuacaacu cuuaaugcaa ucaacaccug caacaggauc aggaucagca      420

auaugcucag gaguagccgu auguaaagua cuacaccuag aaggagaagu caacaaaaua      480

aaaucagccc uccuaaguac aaacaaagcu gucguaucac uauccaaugg uguuucagua      540

cuaacuuuca aaguucuaga ccuaaaaaac uacauagaca aacaacuacu accaauacua      600

aauaaacaaa guuguucuau acccaacaua gaaaccguca uagaauuuca acaaaaaaau      660

aauagacucc uagaaauaac aagagaauuu ucaguuaacg cagguguaac aaccccagua      720

uccaccuaua ugcuaacaaa uucagaauua cuuucccuaa ucaacgacau gcccauaaca      780

aaugaccaaa aaaaauuaau gucaaacaac guccaaauag uucgucaaca aucauauuca      840

auaaugugca uaauaaaaga agaagucuua gccuacguag uacaacuucc ccuuuaugga      900

guuaucgaca cacccugcug gaaacuccac acuucaccac uauguacuac aaacacaaaa      960

gaaggaucca acaucugccu cacaagaacc gaucgaggau gguacuguga uaacgccgga     1020

uccgucucau ucuucccaca agcagaaaca ugcaaaguac aaucaaacag aguauuuugc     1080

gacacaauga acucccucac auuaccuucu gaaguaaacc uauguaaugu agacauauuc     1140

aaccccaaau acgauugcaa aauaaugaca ucaaagacag auguaucauc aagugucauc     1200

acaucccuag gagcaauugu cucauguuau gguaaaacaa aaugcaccgc aucaaauaaa     1260

aacagaggca uaauaaaaac cuucucaaac gguugugacu acguauccaa uaaaggcguc     1320

gacacaguau caguagguaa cacauuauau uguguaaaca aacaagaagg acagucccua     1380

uauguaaaag gagaaccaau aaucaacuuc uacgacccac uuguuuuccc uucugaugaa     1440

uuugacgcaa guauaucaca aguaaaugaa aaaaucaauc aaucacuagc cuuuauaaga     1500

aaaucagaug aauuauuaca caacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaaucgucau aauagucauc cuacuaucac ucauagcagu uggacuccua     1620

cuauacugca aagcacgauc aacaccagua acauuaucca aagaccaacu aagugguauc     1680

aauaacaucg ccuuuucaaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1748
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1748
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau ccucaaagcc      120

aacgcaauca ccacaauccu cacugccguc accuucugcu ucgccuccgg ccaaaacaua      180

acagaagaau uuuaccaauc aaccuguuca gcggucucca aaggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgugaucacc auagaacucu ccaacaucaa ggaaaacaaa      300

ugcaacggca ccgacgcgaa ggucaaacuu auuaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuacaacu ccuaaugcag uccacgccag ccaccggcuc uggcucagcc      420

auaugcuccg guguggccgu augcaaaguc cuacaccucg aaggagaagu caacaaaaua      480

aaauccgccc uacuguccac aaacaaggcc guagucuccc ucucaaacgg cgucucagua      540

cucaccuuca aaguccuaga ccucaagaac uacaucgaca aacaacuccu acccauacua      600

aacaaacaau ccugcucaau ccccaacauc gaaaccguaa uagaauuuca acaaaaaaac      660

aacagacucc uggagaucac ccgggaauuu uccguaaacg ccggagucac aacacccguc      720

ucaaccuaca ugcuaacgaa cucagagcuc cucucacuua ucaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau guccaacaac gugcaaaucg uccgacaaca auccuacucc      840

aucaugugca ucauuaaaga agaaguccuc gcauacguag uccagcuccc ccucuacggc      900

gucauagaca cccccugcug gaaacuacac acaucacccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccgcacc gaccgaggcu gguacugcga uaacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc ugcaaggucc aauccaaccg aguuuucugc     1080

gacacuauga acucgcucac ccuccccucc gaagucaacc ucugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acguauccuc cuccgucauc     1200

accucccuag gcgccauagu aaguugcuac ggcaaaacca agugcacagc aagcaacaaa     1260

aaccgaggaa uaaucaaaac cuucuccaac ggcugcgacu acguauccaa caagggcguc     1320

gacaccguau ccguagggaa cacccuuuac ugcguaaaca aacaagaagg acaaucacuc     1380

uacguaaaag gcgaacccau aaucaacuuc uacgaccccc ucguauuucc cuccgacgaa     1440

uuugacgcau caaucucaca ggucaacgaa aaaauaaacc aaucgcuagc auucaucaga     1500

aaaucagacg aacuccuaca caacgucaac gcaggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgucau aaucgucaua cuacucucac ucauagcagu cggccuccuc     1620

cuauacugua aagcaagguc gaccccaguc acccuaucca aagaccaacu aagcggcauc     1680

aacaacaucg cguucucaaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  1749
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1749
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1750
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1750
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1751
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1751
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1752
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1752
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaccaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1753
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1753
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1754
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1754
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaccaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1755
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1755
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuaaaagca      120

aacgcuauaa caacaauacu aacagcaguc acauucugcu uugcaucagg ccaaaacauc      180

acagaagaau uuuaccaauc aacaugcucc gccguaucga aaggauaccu aggcgcauua      240

agaaccggau gguauacauc agucauaaca auugaacuau cuaacauaaa agaaaacaaa      300

uguaacggca cagaugccaa aguaaaacuc aucaaacaag aauuagauaa auacaaaaac      360

gcagucacug aacuacaacu cuuaaugcaa ucaacaccug caacaggauc aggaucagca      420

auaugcucag gaguagccgu auguaaagua cuacaccuag aaggagaagu caacaaaaua      480

aaaucagccc uccuaaguac aaacaaagcu gucguaucac uauccaaugg uguuucagua      540

cuaacuuuca aaguucuaga ccuaaaaaac uacauagaca aacaacuacu accaauacua      600

aauaaacaaa guuguucuau acccaacaua gaaaccguca uagaauuuca acaaaaaaau      660

aauagacucc uagaaauaac aagagaauuu ucaguuaacg cagguguaac aaccccagua      720

uccaccuaua ugcuaacaaa uucagaauua cuuucccuaa ucaacgacau gcccauaaca      780

aaugaccaaa aaaaauuaau gucaaacaac guccaaauag uucgucaaca aucauauuca      840

auaaugugca uaauaaaaga agaagucuua gccuacguag uacaacuucc ccuuuaugga      900

guuaucgaca cacccugcug gaaacuccac acuucaccac uauguacuac aaacacaaaa      960

gaaggaucca acaucugccu cacaagaacc gaucgaggau gguacuguga uaacgccgga     1020

uccgucucau ucuucccaca agcagaaaca ugcaaaguac aaucaaacag aguauuuugc     1080

gacacaauga acucccucac auuaccuucu gaaguaaacc uauguaaugu agacauauuc     1140

aaccccaaau acgauugcaa aauaaugaca ucaaagacag auguaucauc aagugucauc     1200

acaucccuag gagcaauugu cucauguuau gguaaaacaa aaugcaccgc aucaaauaaa     1260

aacagaggca uaauaaaaac cuucucaaac gguugugacu acguauccaa uaaaggcguc     1320

gacacaguau caguagguaa cacauuauau uguguaaaca aacaagaagg acagucccua     1380

uauguaaaag gagaaccaau aaucaacuuc uacgacccac uuguuuuccc uucugaugaa     1440

uuugacgcaa guauaucaca aguaaaugaa aaaaucaauc aaucacuagc cuuuauaaga     1500

aaaucagaug aauuauuaca caacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaaucgucau aauagucauc cuacuaucac ucauagcagu uggacuccua     1620

cuauacugca aagcacgauc aacaccagua acauuaucca aagaccaacu aagugguauc     1680

aauaacaucg ccuuuucaaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1756
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1756
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau ccucaaagcc      120

aacgcaauca ccacaauccu cacugccguc accuucugcu ucgccuccgg ccaaaacaua      180

acagaagaau uuuaccaauc aaccuguuca gcggucucca aaggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgugaucacc auagaacucu ccaacaucaa ggaaaacaaa      300

ugcaacggca ccgacgcgaa ggucaaacuu auuaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuacaacu ccuaaugcag uccacgccag ccaccggcuc uggcucagcc      420

auaugcuccg guguggccgu augcaaaguc cuacaccucg aaggagaagu caacaaaaua      480

aaauccgccc uacuguccac aaacaaggcc guagucuccc ucucaaacgg cgucucagua      540

cucaccuuca aaguccuaga ccucaagaac uacaucgaca aacaacuccu acccauacua      600

aacaaacaau ccugcucaau ccccaacauc gaaaccguaa uagaauuuca acaaaaaaac      660

aacagacucc uggagaucac ccgggaauuu uccguaaacg ccggagucac aacacccguc      720

ucaaccuaca ugcuaacgaa cucagagcuc cucucacuua ucaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau guccaacaac gugcaaaucg uccgacaaca auccuacucc      840

aucaugugca ucauuaaaga agaaguccuc gcauacguag uccagcuccc ccucuacggc      900

gucauagaca cccccugcug gaaacuacac acaucacccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccgcacc gaccgaggcu gguacugcga uaacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc ugcaaggucc aauccaaccg aguuuucugc     1080

gacacuauga acucgcucac ccuccccucc gaagucaacc ucugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acguauccuc cuccgucauc     1200

accucccuag gcgccauagu aaguugcuac ggcaaaacca agugcacagc aagcaacaaa     1260

aaccgaggaa uaaucaaaac cuucuccaac ggcugcgacu acguauccaa caagggcguc     1320

gacaccguau ccguagggaa cacccuuuac ugcguaaaca aacaagaagg acaaucacuc     1380

uacguaaaag gcgaacccau aaucaacuuc uacgaccccc ucguauuucc cuccgacgaa     1440

uuugacgcau caaucucaca ggucaacgaa aaaauaaacc aaucgcuagc auucaucaga     1500

aaaucagacg aacuccuaca caacgucaac gcaggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgucau aaucgucaua cuacucucac ucauagcagu cggccuccuc     1620

cuauacugua aagcaagguc gaccccaguc acccuaucca aagaccaacu aagcggcauc     1680

aacaacaucg cguucucaaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  1757
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1757
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1758
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1758
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1759
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1759
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1760
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1760
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagacc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1761
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1761
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1762
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1762
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagacc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1763
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1763
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuaaa agcaaacgcu      120

auaacaacaa uacuaacagc agucacauuc ugcuuugcau caggccaaaa caucacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucgaaaggau accuaggcgc auuaagaacc      240

ggaugguaua caucagucau aacaauugaa cuaucuaaca uaaaagaaaa caaauguaac      300

ggcacagaug ccaaaguaaa acucaucaaa caagaauuag auaaauacaa aaacgcaguc      360

acugaacuac aacucuuaau gcaaucaaca ccugcaacag gaucaggauc agcaauaugc      420

ucaggaguag ccguauguaa aguacuacac cuagaaggag aagucaacaa aauaaaauca      480

gcccuccuaa guacaaacaa agcugucgua ucacuaucca augguguuuc aguacuaacu      540

uucaaaguuc uagaccuaaa aaacuacaua gacaaacaac uacuaccaau acuaaauaaa      600

caaaguuguu cuauacccaa cauagaaacc gucauagaau uucaacaaaa aaauaauaga      660

cuccuagaaa uaacaagaga auuuucaguu aacgcaggug uaacaacccc aguauccacc      720

uauaugcuaa caaauucaga auuacuuucc cuaaucaacg acaugcccau aacaaaugac      780

caaaaaaaau uaaugucaaa caacguccaa auaguucguc aacaaucaua uucaauaaug      840

ugcauaauaa aagaagaagu cuuagccuac guaguacaac uuccccuuua uggaguuauc      900

gacacacccu gcuggaaacu ccacacuuca ccacuaugua cuacaaacac aaaagaagga      960

uccaacaucu gccucacaag aaccgaucga ggaugguacu gugauaacgc cggauccguc     1020

ucauucuucc cacaagcaga aacaugcaaa guacaaucaa acagaguauu uugcgacaca     1080

augaacuccc ucacauuacc uucugaagua aaccuaugua auguagacau auucaacccc     1140

aaauacgauu gcaaaauaau gacaucaaag acagauguau caucaagugu caucacaucc     1200

cuaggagcaa uugucucaug uuaugguaaa acaaaaugca ccgcaucaaa uaaaaacaga     1260

ggcauaauaa aaaccuucuc aaacgguugu gacuacguau ccaauaaagg cgucgacaca     1320

guaucaguag guaacacauu auauugugua aacaaacaag aaggacaguc ccuauaugua     1380

aaaggagaac caauaaucaa cuucuacgac ccacuuguuu ucccuucuga ugaauuugac     1440

gcaaguauau cacaaguaaa ugaaaaaauc aaucaaucac uagccuuuau aagaaaauca     1500

gaugaauuau uacacaacgu aaacgccgga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaaucg ucauaauagu cauccuacua ucacucauag caguuggacu ccuacuauac     1620

ugcaaagcac gaucaacacc aguaacauua uccaaagacc aacuaagugg uaucaauaac     1680

aucgccuuuu caaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1764
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1764
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauccucaa agccaacgca      120

aucaccacaa uccucacugc cgucaccuuc ugcuucgccu ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaaccug uucagcgguc uccaaaggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgugau caccauagaa cucuccaaca ucaaggaaaa caaaugcaac      300

ggcaccgacg cgaaggucaa acuuauuaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacuac aacuccuaau gcaguccacg ccagccaccg gcucuggcuc agccauaugc      420

uccggugugg ccguaugcaa aguccuacac cucgaaggag aagucaacaa aauaaaaucc      480

gcccuacugu ccacaaacaa ggccguaguc ucccucucaa acggcgucuc aguacucacc      540

uucaaagucc uagaccucaa gaacuacauc gacaaacaac uccuacccau acuaaacaaa      600

caauccugcu caauccccaa caucgaaacc guaauagaau uucaacaaaa aaacaacaga      660

cuccuggaga ucacccggga auuuuccgua aacgccggag ucacaacacc cgucucaacc      720

uacaugcuaa cgaacucaga gcuccucuca cuuaucaacg acaugcccau aacaaacgac      780

caaaaaaaac ucauguccaa caacgugcaa aucguccgac aacaauccua cuccaucaug      840

ugcaucauua aagaagaagu ccucgcauac guaguccagc ucccccucua cggcgucaua      900

gacacccccu gcuggaaacu acacacauca ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg caccgaccga ggcugguacu gcgauaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccugcaag guccaaucca accgaguuuu cugcgacacu     1080

augaacucgc ucacccuccc cuccgaaguc aaccucugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaag accgacguau ccuccuccgu caucaccucc     1200

cuaggcgcca uaguaaguug cuacggcaaa accaagugca cagcaagcaa caaaaaccga     1260

ggaauaauca aaaccuucuc caacggcugc gacuacguau ccaacaaggg cgucgacacc     1320

guauccguag ggaacacccu uuacugcgua aacaaacaag aaggacaauc acucuacgua     1380

aaaggcgaac ccauaaucaa cuucuacgac ccccucguau uucccuccga cgaauuugac     1440

gcaucaaucu cacaggucaa cgaaaaaaua aaccaaucgc uagcauucau cagaaaauca     1500

gacgaacucc uacacaacgu caacgcaggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ucauaaucgu cauacuacuc ucacucauag cagucggccu ccuccuauac     1620

uguaaagcaa ggucgacccc agucacccua uccaaagacc aacuaagcgg caucaacaac     1680

aucgcguucu caaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  1765
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1765
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1766
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1766
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1767
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1767
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1768
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1768
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagacca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1769
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1769
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1770
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1770
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagacca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1771
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1771
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuaaaa      120

gcaaacgcua uaacaacaau acuaacagca gucacauucu gcuuugcauc aggccaaaac      180

aucacagaag aauuuuacca aucaacaugc uccgccguau cgaaaggaua ccuaggcgca      240

uuaagaaccg gaugguauac aucagucaua acaauugaac uaucuaacau aaaagaaaac      300

aaauguaacg gcacagaugc caaaguaaaa cucaucaaac aagaauuaga uaaauacaaa      360

aacgcaguca cugaacuaca acucuuaaug caaucaacac cugcaacagg aucaggauca      420

gcaauaugcu caggaguagc cguauguaaa guacuacacc uagaaggaga agucaacaaa      480

auaaaaucag cccuccuaag uacaaacaaa gcugucguau cacuauccaa ugguguuuca      540

guacuaacuu ucaaaguucu agaccuaaaa aacuacauag acaaacaacu acuaccaaua      600

cuaaauaaac aaaguuguuc uauacccaac auagaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac uccuagaaau aacaagagaa uuuucaguua acgcaggugu aacaacccca      720

guauccaccu auaugcuaac aaauucagaa uuacuuuccc uaaucaacga caugcccaua      780

acaaaugacc aaaaaaaauu aaugucaaac aacguccaaa uaguucguca acaaucauau      840

ucaauaaugu gcauaauaaa agaagaaguc uuagccuacg uaguacaacu uccccuuuau      900

ggaguuaucg acacacccug cuggaaacuc cacacuucac cacuauguac uacaaacaca      960

aaagaaggau ccaacaucug ccucacaaga accgaucgag gaugguacug ugauaacgcc     1020

ggauccgucu cauucuuccc acaagcagaa acaugcaaag uacaaucaaa cagaguauuu     1080

ugcgacacaa ugaacucccu cacauuaccu ucugaaguaa accuauguaa uguagacaua     1140

uucaacccca aauacgauug caaaauaaug acaucaaaga cagauguauc aucaaguguc     1200

aucacauccc uaggagcaau ugucucaugu uaugguaaaa caaaaugcac cgcaucaaau     1260

aaaaacagag gcauaauaaa aaccuucuca aacgguugug acuacguauc caauaaaggc     1320

gucgacacag uaucaguagg uaacacauua uauuguguaa acaaacaaga aggacagucc     1380

cuauauguaa aaggagaacc aauaaucaac uucuacgacc cacuuguuuu cccuucugau     1440

gaauuugacg caaguauauc acaaguaaau gaaaaaauca aucaaucacu agccuuuaua     1500

agaaaaucag augaauuauu acacaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaaucgu cauaauaguc auccuacuau cacucauagc aguuggacuc     1620

cuacuauacu gcaaagcacg aucaacacca guaacauuau ccaaagacca acuaaguggu     1680

aucaauaaca ucgccuuuuc aaacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1772
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1772
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauccucaaa      120

gccaacgcaa ucaccacaau ccucacugcc gucaccuucu gcuucgccuc cggccaaaac      180

auaacagaag aauuuuacca aucaaccugu ucagcggucu ccaaaggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgugauc accauagaac ucuccaacau caaggaaaac      300

aaaugcaacg gcaccgacgc gaaggucaaa cuuauuaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacuaca acuccuaaug caguccacgc cagccaccgg cucuggcuca      420

gccauaugcu ccgguguggc cguaugcaaa guccuacacc ucgaaggaga agucaacaaa      480

auaaaauccg cccuacuguc cacaaacaag gccguagucu cccucucaaa cggcgucuca      540

guacucaccu ucaaaguccu agaccucaag aacuacaucg acaaacaacu ccuacccaua      600

cuaaacaaac aauccugcuc aauccccaac aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagac uccuggagau cacccgggaa uuuuccguaa acgccggagu cacaacaccc      720

gucucaaccu acaugcuaac gaacucagag cuccucucac uuaucaacga caugcccaua      780

acaaacgacc aaaaaaaacu cauguccaac aacgugcaaa ucguccgaca acaauccuac      840

uccaucaugu gcaucauuaa agaagaaguc cucgcauacg uaguccagcu cccccucuac      900

ggcgucauag acacccccug cuggaaacua cacacaucac cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgc accgaccgag gcugguacug cgauaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accugcaagg uccaauccaa ccgaguuuuc     1080

ugcgacacua ugaacucgcu cacccucccc uccgaaguca accucugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accuccaaga ccgacguauc cuccuccguc     1200

aucaccuccc uaggcgccau aguaaguugc uacggcaaaa ccaagugcac agcaagcaac     1260

aaaaaccgag gaauaaucaa aaccuucucc aacggcugcg acuacguauc caacaagggc     1320

gucgacaccg uauccguagg gaacacccuu uacugcguaa acaaacaaga aggacaauca     1380

cucuacguaa aaggcgaacc cauaaucaac uucuacgacc cccucguauu ucccuccgac     1440

gaauuugacg caucaaucuc acaggucaac gaaaaaauaa accaaucgcu agcauucauc     1500

agaaaaucag acgaacuccu acacaacguc aacgcaggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu cauaaucguc auacuacucu cacucauagc agucggccuc     1620

cuccuauacu guaaagcaag gucgacccca gucacccuau ccaaagacca acuaagcggc     1680

aucaacaaca ucgcguucuc aaacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  1773
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1773
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1774
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1774
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1775
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1775
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1776
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1776
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagacc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1777
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1777
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1778
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1778
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagacc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1779
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1779
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuaaa agcaaacgcu      120

auaacaacaa uacuaacagc agucacauuc ugcuuugcau caggccaaaa caucacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucgaaaggau accuaggcgc auuaagaacc      240

ggaugguaua caucagucau aacaauugaa cuaucuaaca uaaaagaaaa caaauguaac      300

ggcacagaug ccaaaguaaa acucaucaaa caagaauuag auaaauacaa aaacgcaguc      360

acugaacuac aacucuuaau gcaaucaaca ccugcaacag gaucaggauc agcaauaugc      420

ucaggaguag ccguauguaa aguacuacac cuagaaggag aagucaacaa aauaaaauca      480

gcccuccuaa guacaaacaa agcugucgua ucacuaucca augguguuuc aguacuaacu      540

uucaaaguuc uagaccuaaa aaacuacaua gacaaacaac uacuaccaau acuaaauaaa      600

caaaguuguu cuauacccaa cauagaaacc gucauagaau uucaacaaaa aaauaauaga      660

cuccuagaaa uaacaagaga auuuucaguu aacgcaggug uaacaacccc aguauccacc      720

uauaugcuaa caaauucaga auuacuuucc cuaaucaacg acaugcccau aacaaaugac      780

caaaaaaaau uaaugucaaa caacguccaa auaguucguc aacaaucaua uucaauaaug      840

ugcauaauaa aagaagaagu cuuagccuac guaguacaac uuccccuuua uggaguuauc      900

gacacacccu gcuggaaacu ccacacuuca ccacuaugua cuacaaacac aaaagaagga      960

uccaacaucu gccucacaag aaccgaucga ggaugguacu gugauaacgc cggauccguc     1020

ucauucuucc cacaagcaga aacaugcaaa guacaaucaa acagaguauu uugcgacaca     1080

augaacuccc ucacauuacc uucugaagua aaccuaugua auguagacau auucaacccc     1140

aaauacgauu gcaaaauaau gacaucaaag acagauguau caucaagugu caucacaucc     1200

cuaggagcaa uugucucaug uuaugguaaa acaaaaugca ccgcaucaaa uaaaaacaga     1260

ggcauaauaa aaaccuucuc aaacgguugu gacuacguau ccaauaaagg cgucgacaca     1320

guaucaguag guaacacauu auauugugua aacaaacaag aaggacaguc ccuauaugua     1380

aaaggagaac caauaaucaa cuucuacgac ccacuuguuu ucccuucuga ugaauuugac     1440

gcaaguauau cacaaguaaa ugaaaaaauc aaucaaucac uagccuuuau aagaaaauca     1500

gaugaauuau uacacaacgu aaacgccgga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaaucg ucauaauagu cauccuacua ucacucauag caguuggacu ccuacuauac     1620

ugcaaagcac gaucaacacc aguaacauua uccaaagacc aacuaagugg uaucaauaac     1680

aucgccuuuu caaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1780
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1780
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauccucaa agccaacgca      120

aucaccacaa uccucacugc cgucaccuuc ugcuucgccu ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaaccug uucagcgguc uccaaaggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgugau caccauagaa cucuccaaca ucaaggaaaa caaaugcaac      300

ggcaccgacg cgaaggucaa acuuauuaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacuac aacuccuaau gcaguccacg ccagccaccg gcucuggcuc agccauaugc      420

uccggugugg ccguaugcaa aguccuacac cucgaaggag aagucaacaa aauaaaaucc      480

gcccuacugu ccacaaacaa ggccguaguc ucccucucaa acggcgucuc aguacucacc      540

uucaaagucc uagaccucaa gaacuacauc gacaaacaac uccuacccau acuaaacaaa      600

caauccugcu caauccccaa caucgaaacc guaauagaau uucaacaaaa aaacaacaga      660

cuccuggaga ucacccggga auuuuccgua aacgccggag ucacaacacc cgucucaacc      720

uacaugcuaa cgaacucaga gcuccucuca cuuaucaacg acaugcccau aacaaacgac      780

caaaaaaaac ucauguccaa caacgugcaa aucguccgac aacaauccua cuccaucaug      840

ugcaucauua aagaagaagu ccucgcauac guaguccagc ucccccucua cggcgucaua      900

gacacccccu gcuggaaacu acacacauca ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg caccgaccga ggcugguacu gcgauaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccugcaag guccaaucca accgaguuuu cugcgacacu     1080

augaacucgc ucacccuccc cuccgaaguc aaccucugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaag accgacguau ccuccuccgu caucaccucc     1200

cuaggcgcca uaguaaguug cuacggcaaa accaagugca cagcaagcaa caaaaaccga     1260

ggaauaauca aaaccuucuc caacggcugc gacuacguau ccaacaaggg cgucgacacc     1320

guauccguag ggaacacccu uuacugcgua aacaaacaag aaggacaauc acucuacgua     1380

aaaggcgaac ccauaaucaa cuucuacgac ccccucguau uucccuccga cgaauuugac     1440

gcaucaaucu cacaggucaa cgaaaaaaua aaccaaucgc uagcauucau cagaaaauca     1500

gacgaacucc uacacaacgu caacgcaggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ucauaaucgu cauacuacuc ucacucauag cagucggccu ccuccuauac     1620

uguaaagcaa ggucgacccc agucacccua uccaaagacc aacuaagcgg caucaacaac     1680

aucgcguucu caaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  1781
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1781
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1782
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1782
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1783
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1783
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1784
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1784
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaccaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1785
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1785
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1786
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1786
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaccaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1787
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1787
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uaaaagcaaa cgcuauaaca acaauacuaa cagcagucac auucugcuuu      240

gcaucaggcc aaaacaucac agaagaauuu uaccaaucaa caugcuccgc cguaucgaaa      300

ggauaccuag gcgcauuaag aaccggaugg uauacaucag ucauaacaau ugaacuaucu      360

aacauaaaag aaaacaaaug uaacggcaca gaugccaaag uaaaacucau caaacaagaa      420

uuagauaaau acaaaaacgc agucacugaa cuacaacucu uaaugcaauc aacaccugca      480

acaggaucag gaucagcaau augcucagga guagccguau guaaaguacu acaccuagaa      540

ggagaaguca acaaaauaaa aucagcccuc cuaaguacaa acaaagcugu cguaucacua      600

uccaauggug uuucaguacu aacuuucaaa guucuagacc uaaaaaacua cauagacaaa      660

caacuacuac caauacuaaa uaaacaaagu uguucuauac ccaacauaga aaccgucaua      720

gaauuucaac aaaaaaauaa uagacuccua gaaauaacaa gagaauuuuc aguuaacgca      780

gguguaacaa ccccaguauc caccuauaug cuaacaaauu cagaauuacu uucccuaauc      840

aacgacaugc ccauaacaaa ugaccaaaaa aaauuaaugu caaacaacgu ccaaauaguu      900

cgucaacaau cauauucaau aaugugcaua auaaaagaag aagucuuagc cuacguagua      960

caacuucccc uuuauggagu uaucgacaca cccugcugga aacuccacac uucaccacua     1020

uguacuacaa acacaaaaga aggauccaac aucugccuca caagaaccga ucgaggaugg     1080

uacugugaua acgccggauc cgucucauuc uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuugcga cacaaugaac ucccucacau uaccuucuga aguaaaccua     1200

uguaauguag acauauucaa ccccaaauac gauugcaaaa uaaugacauc aaagacagau     1260

guaucaucaa gugucaucac aucccuagga gcaauugucu cauguuaugg uaaaacaaaa     1320

ugcaccgcau caaauaaaaa cagaggcaua auaaaaaccu ucucaaacgg uugugacuac     1380

guauccaaua aaggcgucga cacaguauca guagguaaca cauuauauug uguaaacaaa     1440

caagaaggac agucccuaua uguaaaagga gaaccaauaa ucaacuucua cgacccacuu     1500

guuuucccuu cugaugaauu ugacgcaagu auaucacaag uaaaugaaaa aaucaaucaa     1560

ucacuagccu uuauaagaaa aucagaugaa uuauuacaca acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua aucgucauaa uagucauccu acuaucacuc     1680

auagcaguug gacuccuacu auacugcaaa gcacgaucaa caccaguaac auuauccaaa     1740

gaccaacuaa gugguaucaa uaacaucgcc uuuucaaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1788
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1788
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaaucc ucaaagccaa cgcaaucacc acaauccuca cugccgucac cuucugcuuc      240

gccuccggcc aaaacauaac agaagaauuu uaccaaucaa ccuguucagc ggucuccaaa      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ugaucaccau agaacucucc      360

aacaucaagg aaaacaaaug caacggcacc gacgcgaagg ucaaacuuau uaaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuacaacucc uaaugcaguc cacgccagcc      480

accggcucug gcucagccau augcuccggu guggccguau gcaaaguccu acaccucgaa      540

ggagaaguca acaaaauaaa auccgcccua cuguccacaa acaaggccgu agucucccuc      600

ucaaacggcg ucucaguacu caccuucaaa guccuagacc ucaagaacua caucgacaaa      660

caacuccuac ccauacuaaa caaacaaucc ugcucaaucc ccaacaucga aaccguaaua      720

gaauuucaac aaaaaaacaa cagacuccug gagaucaccc gggaauuuuc cguaaacgcc      780

ggagucacaa cacccgucuc aaccuacaug cuaacgaacu cagagcuccu cucacuuauc      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu ccaacaacgu gcaaaucguc      900

cgacaacaau ccuacuccau caugugcauc auuaaagaag aaguccucgc auacguaguc      960

cagcuccccc ucuacggcgu cauagacacc cccugcugga aacuacacac aucaccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccgcaccga ccgaggcugg     1080

uacugcgaua acgccggcag cgucuccuuc uucccccaag cagaaaccug caagguccaa     1140

uccaaccgag uuuucugcga cacuaugaac ucgcucaccc uccccuccga agucaaccuc     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

guauccuccu ccgucaucac cucccuaggc gccauaguaa guugcuacgg caaaaccaag     1320

ugcacagcaa gcaacaaaaa ccgaggaaua aucaaaaccu ucuccaacgg cugcgacuac     1380

guauccaaca agggcgucga caccguaucc guagggaaca cccuuuacug cguaaacaaa     1440

caagaaggac aaucacucua cguaaaaggc gaacccauaa ucaacuucua cgacccccuc     1500

guauuucccu ccgacgaauu ugacgcauca aucucacagg ucaacgaaaa aauaaaccaa     1560

ucgcuagcau ucaucagaaa aucagacgaa cuccuacaca acgucaacgc aggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgucauaa ucgucauacu acucucacuc     1680

auagcagucg gccuccuccu auacuguaaa gcaaggucga ccccagucac ccuauccaaa     1740

gaccaacuaa gcggcaucaa caacaucgcg uucucaaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  1789
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1789
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1790
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1790
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1791
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1791
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1792
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1792
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaccaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1793
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1793
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1794
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1794
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaccaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1795
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1795
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac      120

uaacagcagu cacauucugc uuugcaucag gccaaaacau cacagaagaa uuuuaccaau      180

caacaugcuc cgccguaucg aaaggauacc uaggcgcauu aagaaccgga ugguauacau      240

cagucauaac aauugaacua ucuaacauaa aagaaaacaa auguaacggc acagaugcca      300

aaguaaaacu caucaaacaa gaauuagaua aauacaaaaa cgcagucacu gaacuacaac      360

ucuuaaugca aucaacaccu gcaacaggau caggaucagc aauaugcuca ggaguagccg      420

uauguaaagu acuacaccua gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua      480

caaacaaagc ugucguauca cuauccaaug guguuucagu acuaacuuuc aaaguucuag      540

accuaaaaaa cuacauagac aaacaacuac uaccaauacu aaauaaacaa aguuguucua      600

uacccaacau agaaaccguc auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa      660

caagagaauu uucaguuaac gcagguguaa caaccccagu auccaccuau augcuaacaa      720

auucagaauu acuuucccua aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa      780

ugucaaacaa cguccaaaua guucgucaac aaucauauuc aauaaugugc auaauaaaag      840

aagaagucuu agccuacgua guacaacuuc cccuuuaugg aguuaucgac acacccugcu      900

ggaaacucca cacuucacca cuauguacua caaacacaaa agaaggaucc aacaucugcc      960

ucacaagaac cgaucgagga ugguacugug auaacgccgg auccgucuca uucuucccac     1020

aagcagaaac augcaaagua caaucaaaca gaguauuuug cgacacaaug aacucccuca     1080

cauuaccuuc ugaaguaaac cuauguaaug uagacauauu caaccccaaa uacgauugca     1140

aaauaaugac aucaaagaca gauguaucau caagugucau cacaucccua ggagcaauug     1200

ucucauguua ugguaaaaca aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa     1260

ccuucucaaa cgguugugac uacguaucca auaaaggcgu cgacacagua ucaguaggua     1320

acacauuaua uuguguaaac aaacaagaag gacagucccu auauguaaaa ggagaaccaa     1380

uaaucaacuu cuacgaccca cuuguuuucc cuucugauga auuugacgca aguauaucac     1440

aaguaaauga aaaaaucaau caaucacuag ccuuuauaag aaaaucagau gaauuauuac     1500

acaacguaaa cgccggaaaa ucaacaacca acauaaugau aaccacaaua auaaucguca     1560

uaauagucau ccuacuauca cucauagcag uuggacuccu acuauacugc aaagcacgau     1620

caacaccagu aacauuaucc aaagaccaac uaagugguau caauaacauc gccuuuucaa     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1796
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1796
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uccucaaagc caacgcaauc accacaaucc      120

ucacugccgu caccuucugc uucgccuccg gccaaaacau aacagaagaa uuuuaccaau      180

caaccuguuc agcggucucc aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgugaucac cauagaacuc uccaacauca aggaaaacaa augcaacggc accgacgcga      300

aggucaaacu uauuaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuacaac      360

uccuaaugca guccacgcca gccaccggcu cuggcucagc cauaugcucc gguguggccg      420

uaugcaaagu ccuacaccuc gaaggagaag ucaacaaaau aaaauccgcc cuacugucca      480

caaacaaggc cguagucucc cucucaaacg gcgucucagu acucaccuuc aaaguccuag      540

accucaagaa cuacaucgac aaacaacucc uacccauacu aaacaaacaa uccugcucaa      600

uccccaacau cgaaaccgua auagaauuuc aacaaaaaaa caacagacuc cuggagauca      660

cccgggaauu uuccguaaac gccggaguca caacacccgu cucaaccuac augcuaacga      720

acucagagcu ccucucacuu aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

uguccaacaa cgugcaaauc guccgacaac aauccuacuc caucaugugc aucauuaaag      840

aagaaguccu cgcauacgua guccagcucc cccucuacgg cgucauagac acccccugcu      900

ggaaacuaca cacaucaccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccgcac cgaccgaggc ugguacugcg auaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cugcaagguc caauccaacc gaguuuucug cgacacuaug aacucgcuca     1080

cccuccccuc cgaagucaac cucugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cuccaagacc gacguauccu ccuccgucau caccucccua ggcgccauag     1200

uaaguugcua cggcaaaacc aagugcacag caagcaacaa aaaccgagga auaaucaaaa     1260

ccuucuccaa cggcugcgac uacguaucca acaagggcgu cgacaccgua uccguaggga     1320

acacccuuua cugcguaaac aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca     1380

uaaucaacuu cuacgacccc cucguauuuc ccuccgacga auuugacgca ucaaucucac     1440

aggucaacga aaaaauaaac caaucgcuag cauucaucag aaaaucagac gaacuccuac     1500

acaacgucaa cgcaggcaag agcaccacca acaucaugau caccaccauc aucaucguca     1560

uaaucgucau acuacucuca cucauagcag ucggccuccu ccuauacugu aaagcaaggu     1620

cgaccccagu cacccuaucc aaagaccaac uaagcggcau caacaacauc gcguucucaa     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  1797
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1797
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1798
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1798
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1799
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1799
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1800
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1800
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaccaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1801
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1801
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1802
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1802
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaccaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1803
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1803
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uaaaagcaaa cgcuauaaca acaauacuaa cagcagucac auucugcuuu      240

gcaucaggcc aaaacaucac agaagaauuu uaccaaucaa caugcuccgc cguaucgaaa      300

ggauaccuag gcgcauuaag aaccggaugg uauacaucag ucauaacaau ugaacuaucu      360

aacauaaaag aaaacaaaug uaacggcaca gaugccaaag uaaaacucau caaacaagaa      420

uuagauaaau acaaaaacgc agucacugaa cuacaacucu uaaugcaauc aacaccugca      480

acaggaucag gaucagcaau augcucagga guagccguau guaaaguacu acaccuagaa      540

ggagaaguca acaaaauaaa aucagcccuc cuaaguacaa acaaagcugu cguaucacua      600

uccaauggug uuucaguacu aacuuucaaa guucuagacc uaaaaaacua cauagacaaa      660

caacuacuac caauacuaaa uaaacaaagu uguucuauac ccaacauaga aaccgucaua      720

gaauuucaac aaaaaaauaa uagacuccua gaaauaacaa gagaauuuuc aguuaacgca      780

gguguaacaa ccccaguauc caccuauaug cuaacaaauu cagaauuacu uucccuaauc      840

aacgacaugc ccauaacaaa ugaccaaaaa aaauuaaugu caaacaacgu ccaaauaguu      900

cgucaacaau cauauucaau aaugugcaua auaaaagaag aagucuuagc cuacguagua      960

caacuucccc uuuauggagu uaucgacaca cccugcugga aacuccacac uucaccacua     1020

uguacuacaa acacaaaaga aggauccaac aucugccuca caagaaccga ucgaggaugg     1080

uacugugaua acgccggauc cgucucauuc uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuugcga cacaaugaac ucccucacau uaccuucuga aguaaaccua     1200

uguaauguag acauauucaa ccccaaauac gauugcaaaa uaaugacauc aaagacagau     1260

guaucaucaa gugucaucac aucccuagga gcaauugucu cauguuaugg uaaaacaaaa     1320

ugcaccgcau caaauaaaaa cagaggcaua auaaaaaccu ucucaaacgg uugugacuac     1380

guauccaaua aaggcgucga cacaguauca guagguaaca cauuauauug uguaaacaaa     1440

caagaaggac agucccuaua uguaaaagga gaaccaauaa ucaacuucua cgacccacuu     1500

guuuucccuu cugaugaauu ugacgcaagu auaucacaag uaaaugaaaa aaucaaucaa     1560

ucacuagccu uuauaagaaa aucagaugaa uuauuacaca acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua aucgucauaa uagucauccu acuaucacuc     1680

auagcaguug gacuccuacu auacugcaaa gcacgaucaa caccaguaac auuauccaaa     1740

gaccaacuaa gugguaucaa uaacaucgcc uuuucaaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1804
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1804
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaaucc ucaaagccaa cgcaaucacc acaauccuca cugccgucac cuucugcuuc      240

gccuccggcc aaaacauaac agaagaauuu uaccaaucaa ccuguucagc ggucuccaaa      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ugaucaccau agaacucucc      360

aacaucaagg aaaacaaaug caacggcacc gacgcgaagg ucaaacuuau uaaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuacaacucc uaaugcaguc cacgccagcc      480

accggcucug gcucagccau augcuccggu guggccguau gcaaaguccu acaccucgaa      540

ggagaaguca acaaaauaaa auccgcccua cuguccacaa acaaggccgu agucucccuc      600

ucaaacggcg ucucaguacu caccuucaaa guccuagacc ucaagaacua caucgacaaa      660

caacuccuac ccauacuaaa caaacaaucc ugcucaaucc ccaacaucga aaccguaaua      720

gaauuucaac aaaaaaacaa cagacuccug gagaucaccc gggaauuuuc cguaaacgcc      780

ggagucacaa cacccgucuc aaccuacaug cuaacgaacu cagagcuccu cucacuuauc      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu ccaacaacgu gcaaaucguc      900

cgacaacaau ccuacuccau caugugcauc auuaaagaag aaguccucgc auacguaguc      960

cagcuccccc ucuacggcgu cauagacacc cccugcugga aacuacacac aucaccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccgcaccga ccgaggcugg     1080

uacugcgaua acgccggcag cgucuccuuc uucccccaag cagaaaccug caagguccaa     1140

uccaaccgag uuuucugcga cacuaugaac ucgcucaccc uccccuccga agucaaccuc     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

guauccuccu ccgucaucac cucccuaggc gccauaguaa guugcuacgg caaaaccaag     1320

ugcacagcaa gcaacaaaaa ccgaggaaua aucaaaaccu ucuccaacgg cugcgacuac     1380

guauccaaca agggcgucga caccguaucc guagggaaca cccuuuacug cguaaacaaa     1440

caagaaggac aaucacucua cguaaaaggc gaacccauaa ucaacuucua cgacccccuc     1500

guauuucccu ccgacgaauu ugacgcauca aucucacagg ucaacgaaaa aauaaaccaa     1560

ucgcuagcau ucaucagaaa aucagacgaa cuccuacaca acgucaacgc aggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgucauaa ucgucauacu acucucacuc     1680

auagcagucg gccuccuccu auacuguaaa gcaaggucga ccccagucac ccuauccaaa     1740

gaccaacuaa gcggcaucaa caacaucgcg uucucaaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  1805
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1805
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1806
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1806
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      540

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1380

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1680

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1807
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1807
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1808
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1808
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      480

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      540

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      600

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      720

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      780

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      840

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua      900

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc      960

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg     1020

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1080

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1140

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1200

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1260

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1320

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1380

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1440

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1500

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1560

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1620

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1680

aaagaccaac ucucugggau aaacaauauc gcauucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1809
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1809
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1810
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1810
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      480

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      540

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      600

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      720

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      780

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      840

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      900

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc      960

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc     1020

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1080

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1140

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1200

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1260

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1320

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1380

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1440

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1500

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1620

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1680

aaagaccaac ucuccggaau uaacaauauc gcuuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1811
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1811
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac uaacagcagu cacauucugc      180

uuugcaucag gccaaaacau cacagaagaa uuuuaccaau caacaugcuc cgccguaucg      240

aaaggauacc uaggcgcauu aagaaccgga ugguauacau cagucauaac aauugaacua      300

ucuaacauaa aagaaaacaa auguaacggc acagaugcca aaguaaaacu caucaaacaa      360

gaauuagaua aauacaaaaa cgcagucacu gaacuacaac ucuuaaugca aucaacaccu      420

gcaacaggau caggaucagc aauaugcuca ggaguagccg uauguaaagu acuacaccua      480

gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua caaacaaagc ugucguauca      540

cuauccaaug guguuucagu acuaacuuuc aaaguucuag accuaaaaaa cuacauagac      600

aaacaacuac uaccaauacu aaauaaacaa aguuguucua uacccaacau agaaaccguc      660

auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa caagagaauu uucaguuaac      720

gcagguguaa caaccccagu auccaccuau augcuaacaa auucagaauu acuuucccua      780

aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa ugucaaacaa cguccaaaua      840

guucgucaac aaucauauuc aauaaugugc auaauaaaag aagaagucuu agccuacgua      900

guacaacuuc cccuuuaugg aguuaucgac acacccugcu ggaaacucca cacuucacca      960

cuauguacua caaacacaaa agaaggaucc aacaucugcc ucacaagaac cgaucgagga     1020

ugguacugug auaacgccgg auccgucuca uucuucccac aagcagaaac augcaaagua     1080

caaucaaaca gaguauuuug cgacacaaug aacucccuca cauuaccuuc ugaaguaaac     1140

cuauguaaug uagacauauu caaccccaaa uacgauugca aaauaaugac aucaaagaca     1200

gauguaucau caagugucau cacaucccua ggagcaauug ucucauguua ugguaaaaca     1260

aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa ccuucucaaa cgguugugac     1320

uacguaucca auaaaggcgu cgacacagua ucaguaggua acacauuaua uuguguaaac     1380

aaacaagaag gacagucccu auauguaaaa ggagaaccaa uaaucaacuu cuacgaccca     1440

cuuguuuucc cuucugauga auuugacgca aguauaucac aaguaaauga aaaaaucaau     1500

caaucacuag ccuuuauaag aaaaucagau gaauuauuac acaacguaaa cgccggaaaa     1560

ucaacaacca acauaaugau aaccacaaua auaaucguca uaauagucau ccuacuauca     1620

cucauagcag uuggacuccu acuauacugc aaagcacgau caacaccagu aacauuaucc     1680

aaagaccaac uaagugguau caauaacauc gccuuuucaa acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1812
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1812
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuaa uccucaaagc caacgcaauc accacaaucc ucacugccgu caccuucugc      180

uucgccuccg gccaaaacau aacagaagaa uuuuaccaau caaccuguuc agcggucucc      240

aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgugaucac cauagaacuc      300

uccaacauca aggaaaacaa augcaacggc accgacgcga aggucaaacu uauuaaacaa      360

gaacucgaca aauacaaaaa cgcagucacc gaacuacaac uccuaaugca guccacgcca      420

gccaccggcu cuggcucagc cauaugcucc gguguggccg uaugcaaagu ccuacaccuc      480

gaaggagaag ucaacaaaau aaaauccgcc cuacugucca caaacaaggc cguagucucc      540

cucucaaacg gcgucucagu acucaccuuc aaaguccuag accucaagaa cuacaucgac      600

aaacaacucc uacccauacu aaacaaacaa uccugcucaa uccccaacau cgaaaccgua      660

auagaauuuc aacaaaaaaa caacagacuc cuggagauca cccgggaauu uuccguaaac      720

gccggaguca caacacccgu cucaaccuac augcuaacga acucagagcu ccucucacuu      780

aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca uguccaacaa cgugcaaauc      840

guccgacaac aauccuacuc caucaugugc aucauuaaag aagaaguccu cgcauacgua      900

guccagcucc cccucuacgg cgucauagac acccccugcu ggaaacuaca cacaucaccc      960

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccgcac cgaccgaggc     1020

ugguacugcg auaacgccgg cagcgucucc uucuuccccc aagcagaaac cugcaagguc     1080

caauccaacc gaguuuucug cgacacuaug aacucgcuca cccuccccuc cgaagucaac     1140

cucugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cuccaagacc     1200

gacguauccu ccuccgucau caccucccua ggcgccauag uaaguugcua cggcaaaacc     1260

aagugcacag caagcaacaa aaaccgagga auaaucaaaa ccuucuccaa cggcugcgac     1320

uacguaucca acaagggcgu cgacaccgua uccguaggga acacccuuua cugcguaaac     1380

aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca uaaucaacuu cuacgacccc     1440

cucguauuuc ccuccgacga auuugacgca ucaaucucac aggucaacga aaaaauaaac     1500

caaucgcuag cauucaucag aaaaucagac gaacuccuac acaacgucaa cgcaggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguca uaaucgucau acuacucuca     1620

cucauagcag ucggccuccu ccuauacugu aaagcaaggu cgaccccagu cacccuaucc     1680

aaagaccaac uaagcggcau caacaacauc gcguucucaa acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  1813
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1813
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1814
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1814
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1815
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1815
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1816
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1816
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagacca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1817
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1817
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1818
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1818
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagacca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1819
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1819
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuaaaa      120

gcaaacgcua uaacaacaau acuaacagca gucacauucu gcuuugcauc aggccaaaac      180

aucacagaag aauuuuacca aucaacaugc uccgccguau cgaaaggaua ccuaggcgca      240

uuaagaaccg gaugguauac aucagucaua acaauugaac uaucuaacau aaaagaaaac      300

aaauguaacg gcacagaugc caaaguaaaa cucaucaaac aagaauuaga uaaauacaaa      360

aacgcaguca cugaacuaca acucuuaaug caaucaacac cugcaacagg aucaggauca      420

gcaauaugcu caggaguagc cguauguaaa guacuacacc uagaaggaga agucaacaaa      480

auaaaaucag cccuccuaag uacaaacaaa gcugucguau cacuauccaa ugguguuuca      540

guacuaacuu ucaaaguucu agaccuaaaa aacuacauag acaaacaacu acuaccaaua      600

cuaaauaaac aaaguuguuc uauacccaac auagaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac uccuagaaau aacaagagaa uuuucaguua acgcaggugu aacaacccca      720

guauccaccu auaugcuaac aaauucagaa uuacuuuccc uaaucaacga caugcccaua      780

acaaaugacc aaaaaaaauu aaugucaaac aacguccaaa uaguucguca acaaucauau      840

ucaauaaugu gcauaauaaa agaagaaguc uuagccuacg uaguacaacu uccccuuuau      900

ggaguuaucg acacacccug cuggaaacuc cacacuucac cacuauguac uacaaacaca      960

aaagaaggau ccaacaucug ccucacaaga accgaucgag gaugguacug ugauaacgcc     1020

ggauccgucu cauucuuccc acaagcagaa acaugcaaag uacaaucaaa cagaguauuu     1080

ugcgacacaa ugaacucccu cacauuaccu ucugaaguaa accuauguaa uguagacaua     1140

uucaacccca aauacgauug caaaauaaug acaucaaaga cagauguauc aucaaguguc     1200

aucacauccc uaggagcaau ugucucaugu uaugguaaaa caaaaugcac cgcaucaaau     1260

aaaaacagag gcauaauaaa aaccuucuca aacgguugug acuacguauc caauaaaggc     1320

gucgacacag uaucaguagg uaacacauua uauuguguaa acaaacaaga aggacagucc     1380

cuauauguaa aaggagaacc aauaaucaac uucuacgacc cacuuguuuu cccuucugau     1440

gaauuugacg caaguauauc acaaguaaau gaaaaaauca aucaaucacu agccuuuaua     1500

agaaaaucag augaauuauu acacaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaaucgu cauaauaguc auccuacuau cacucauagc aguuggacuc     1620

cuacuauacu gcaaagcacg aucaacacca guaacauuau ccaaagacca acuaaguggu     1680

aucaauaaca ucgccuuuuc aaacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1820
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1820
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauccucaaa      120

gccaacgcaa ucaccacaau ccucacugcc gucaccuucu gcuucgccuc cggccaaaac      180

auaacagaag aauuuuacca aucaaccugu ucagcggucu ccaaaggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgugauc accauagaac ucuccaacau caaggaaaac      300

aaaugcaacg gcaccgacgc gaaggucaaa cuuauuaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacuaca acuccuaaug caguccacgc cagccaccgg cucuggcuca      420

gccauaugcu ccgguguggc cguaugcaaa guccuacacc ucgaaggaga agucaacaaa      480

auaaaauccg cccuacuguc cacaaacaag gccguagucu cccucucaaa cggcgucuca      540

guacucaccu ucaaaguccu agaccucaag aacuacaucg acaaacaacu ccuacccaua      600

cuaaacaaac aauccugcuc aauccccaac aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagac uccuggagau cacccgggaa uuuuccguaa acgccggagu cacaacaccc      720

gucucaaccu acaugcuaac gaacucagag cuccucucac uuaucaacga caugcccaua      780

acaaacgacc aaaaaaaacu cauguccaac aacgugcaaa ucguccgaca acaauccuac      840

uccaucaugu gcaucauuaa agaagaaguc cucgcauacg uaguccagcu cccccucuac      900

ggcgucauag acacccccug cuggaaacua cacacaucac cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgc accgaccgag gcugguacug cgauaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accugcaagg uccaauccaa ccgaguuuuc     1080

ugcgacacua ugaacucgcu cacccucccc uccgaaguca accucugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accuccaaga ccgacguauc cuccuccguc     1200

aucaccuccc uaggcgccau aguaaguugc uacggcaaaa ccaagugcac agcaagcaac     1260

aaaaaccgag gaauaaucaa aaccuucucc aacggcugcg acuacguauc caacaagggc     1320

gucgacaccg uauccguagg gaacacccuu uacugcguaa acaaacaaga aggacaauca     1380

cucuacguaa aaggcgaacc cauaaucaac uucuacgacc cccucguauu ucccuccgac     1440

gaauuugacg caucaaucuc acaggucaac gaaaaaauaa accaaucgcu agcauucauc     1500

agaaaaucag acgaacuccu acacaacguc aacgcaggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu cauaaucguc auacuacucu cacucauagc agucggccuc     1620

cuccuauacu guaaagcaag gucgacccca gucacccuau ccaaagacca acuaagcggc     1680

aucaacaaca ucgcguucuc aaacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  1821
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1821
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1822
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1822
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1823
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1823
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1824
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1824
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagacca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1825
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1825
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1826
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1826
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagacca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1827
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1827
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuaaaa gcaaacgcua uaacaacaau acuaacagca      120

gucacauucu gcuuugcauc aggccaaaac aucacagaag aauuuuacca aucaacaugc      180

uccgccguau cgaaaggaua ccuaggcgca uuaagaaccg gaugguauac aucagucaua      240

acaauugaac uaucuaacau aaaagaaaac aaauguaacg gcacagaugc caaaguaaaa      300

cucaucaaac aagaauuaga uaaauacaaa aacgcaguca cugaacuaca acucuuaaug      360

caaucaacac cugcaacagg aucaggauca gcaauaugcu caggaguagc cguauguaaa      420

guacuacacc uagaaggaga agucaacaaa auaaaaucag cccuccuaag uacaaacaaa      480

gcugucguau cacuauccaa ugguguuuca guacuaacuu ucaaaguucu agaccuaaaa      540

aacuacauag acaaacaacu acuaccaaua cuaaauaaac aaaguuguuc uauacccaac      600

auagaaaccg ucauagaauu ucaacaaaaa aauaauagac uccuagaaau aacaagagaa      660

uuuucaguua acgcaggugu aacaacccca guauccaccu auaugcuaac aaauucagaa      720

uuacuuuccc uaaucaacga caugcccaua acaaaugacc aaaaaaaauu aaugucaaac      780

aacguccaaa uaguucguca acaaucauau ucaauaaugu gcauaauaaa agaagaaguc      840

uuagccuacg uaguacaacu uccccuuuau ggaguuaucg acacacccug cuggaaacuc      900

cacacuucac cacuauguac uacaaacaca aaagaaggau ccaacaucug ccucacaaga      960

accgaucgag gaugguacug ugauaacgcc ggauccgucu cauucuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa cagaguauuu ugcgacacaa ugaacucccu cacauuaccu     1080

ucugaaguaa accuauguaa uguagacaua uucaacccca aauacgauug caaaauaaug     1140

acaucaaaga cagauguauc aucaaguguc aucacauccc uaggagcaau ugucucaugu     1200

uaugguaaaa caaaaugcac cgcaucaaau aaaaacagag gcauaauaaa aaccuucuca     1260

aacgguugug acuacguauc caauaaaggc gucgacacag uaucaguagg uaacacauua     1320

uauuguguaa acaaacaaga aggacagucc cuauauguaa aaggagaacc aauaaucaac     1380

uucuacgacc cacuuguuuu cccuucugau gaauuugacg caaguauauc acaaguaaau     1440

gaaaaaauca aucaaucacu agccuuuaua agaaaaucag augaauuauu acacaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaaccacaa uaauaaucgu cauaauaguc     1560

auccuacuau cacucauagc aguuggacuc cuacuauacu gcaaagcacg aucaacacca     1620

guaacauuau ccaaagacca acuaaguggu aucaauaaca ucgccuuuuc aaacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1828
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1828
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauccucaaa gccaacgcaa ucaccacaau ccucacugcc      120

gucaccuucu gcuucgccuc cggccaaaac auaacagaag aauuuuacca aucaaccugu      180

ucagcggucu ccaaaggcua ccucggcgcc cuccgcaccg gcugguacac cuccgugauc      240

accauagaac ucuccaacau caaggaaaac aaaugcaacg gcaccgacgc gaaggucaaa      300

cuuauuaaac aagaacucga caaauacaaa aacgcaguca ccgaacuaca acuccuaaug      360

caguccacgc cagccaccgg cucuggcuca gccauaugcu ccgguguggc cguaugcaaa      420

guccuacacc ucgaaggaga agucaacaaa auaaaauccg cccuacuguc cacaaacaag      480

gccguagucu cccucucaaa cggcgucuca guacucaccu ucaaaguccu agaccucaag      540

aacuacaucg acaaacaacu ccuacccaua cuaaacaaac aauccugcuc aauccccaac      600

aucgaaaccg uaauagaauu ucaacaaaaa aacaacagac uccuggagau cacccgggaa      660

uuuuccguaa acgccggagu cacaacaccc gucucaaccu acaugcuaac gaacucagag      720

cuccucucac uuaucaacga caugcccaua acaaacgacc aaaaaaaacu cauguccaac      780

aacgugcaaa ucguccgaca acaauccuac uccaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg uaguccagcu cccccucuac ggcgucauag acacccccug cuggaaacua      900

cacacaucac cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgc      960

accgaccgag gcugguacug cgauaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accugcaagg uccaauccaa ccgaguuuuc ugcgacacua ugaacucgcu cacccucccc     1080

uccgaaguca accucugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accuccaaga ccgacguauc cuccuccguc aucaccuccc uaggcgccau aguaaguugc     1200

uacggcaaaa ccaagugcac agcaagcaac aaaaaccgag gaauaaucaa aaccuucucc     1260

aacggcugcg acuacguauc caacaagggc gucgacaccg uauccguagg gaacacccuu     1320

uacugcguaa acaaacaaga aggacaauca cucuacguaa aaggcgaacc cauaaucaac     1380

uucuacgacc cccucguauu ucccuccgac gaauuugacg caucaaucuc acaggucaac     1440

gaaaaaauaa accaaucgcu agcauucauc agaaaaucag acgaacuccu acacaacguc     1500

aacgcaggca agagcaccac caacaucaug aucaccacca ucaucaucgu cauaaucguc     1560

auacuacucu cacucauagc agucggccuc cuccuauacu guaaagcaag gucgacccca     1620

gucacccuau ccaaagacca acuaagcggc aucaacaaca ucgcguucuc aaacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  1829
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1829
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1830
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1830
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1831
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1831
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1832
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1832
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag accaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1833
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1833
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1834
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1834
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag accaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1835
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1835
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu aaaagcaaac gcuauaacaa caauacuaac agcagucaca      180

uucugcuuug caucaggcca aaacaucaca gaagaauuuu accaaucaac augcuccgcc      240

guaucgaaag gauaccuagg cgcauuaaga accggauggu auacaucagu cauaacaauu      300

gaacuaucua acauaaaaga aaacaaaugu aacggcacag augccaaagu aaaacucauc      360

aaacaagaau uagauaaaua caaaaacgca gucacugaac uacaacucuu aaugcaauca      420

acaccugcaa caggaucagg aucagcaaua ugcucaggag uagccguaug uaaaguacua      480

caccuagaag gagaagucaa caaaauaaaa ucagcccucc uaaguacaaa caaagcuguc      540

guaucacuau ccaauggugu uucaguacua acuuucaaag uucuagaccu aaaaaacuac      600

auagacaaac aacuacuacc aauacuaaau aaacaaaguu guucuauacc caacauagaa      660

accgucauag aauuucaaca aaaaaauaau agacuccuag aaauaacaag agaauuuuca      720

guuaacgcag guguaacaac cccaguaucc accuauaugc uaacaaauuc agaauuacuu      780

ucccuaauca acgacaugcc cauaacaaau gaccaaaaaa aauuaauguc aaacaacguc      840

caaauaguuc gucaacaauc auauucaaua augugcauaa uaaaagaaga agucuuagcc      900

uacguaguac aacuuccccu uuauggaguu aucgacacac ccugcuggaa acuccacacu      960

ucaccacuau guacuacaaa cacaaaagaa ggauccaaca ucugccucac aagaaccgau     1020

cgaggauggu acugugauaa cgccggaucc gucucauucu ucccacaagc agaaacaugc     1080

aaaguacaau caaacagagu auuuugcgac acaaugaacu cccucacauu accuucugaa     1140

guaaaccuau guaauguaga cauauucaac cccaaauacg auugcaaaau aaugacauca     1200

aagacagaug uaucaucaag ugucaucaca ucccuaggag caauugucuc auguuauggu     1260

aaaacaaaau gcaccgcauc aaauaaaaac agaggcauaa uaaaaaccuu cucaaacggu     1320

ugugacuacg uauccaauaa aggcgucgac acaguaucag uagguaacac auuauauugu     1380

guaaacaaac aagaaggaca gucccuauau guaaaaggag aaccaauaau caacuucuac     1440

gacccacuug uuuucccuuc ugaugaauuu gacgcaagua uaucacaagu aaaugaaaaa     1500

aucaaucaau cacuagccuu uauaagaaaa ucagaugaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa ucgucauaau agucauccua     1620

cuaucacuca uagcaguugg acuccuacua uacugcaaag cacgaucaac accaguaaca     1680

uuauccaaag accaacuaag ugguaucaau aacaucgccu uuucaaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1836
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1836
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauccu caaagccaac gcaaucacca caauccucac ugccgucacc      180

uucugcuucg ccuccggcca aaacauaaca gaagaauuuu accaaucaac cuguucagcg      240

gucuccaaag gcuaccucgg cgcccuccgc accggcuggu acaccuccgu gaucaccaua      300

gaacucucca acaucaagga aaacaaaugc aacggcaccg acgcgaaggu caaacuuauu      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uacaacuccu aaugcagucc      420

acgccagcca ccggcucugg cucagccaua ugcuccggug uggccguaug caaaguccua      480

caccucgaag gagaagucaa caaaauaaaa uccgcccuac uguccacaaa caaggccgua      540

gucucccucu caaacggcgu cucaguacuc accuucaaag uccuagaccu caagaacuac      600

aucgacaaac aacuccuacc cauacuaaac aaacaauccu gcucaauccc caacaucgaa      660

accguaauag aauuucaaca aaaaaacaac agacuccugg agaucacccg ggaauuuucc      720

guaaacgccg gagucacaac acccgucuca accuacaugc uaacgaacuc agagcuccuc      780

ucacuuauca acgacaugcc cauaacaaac gaccaaaaaa aacucauguc caacaacgug      840

caaaucgucc gacaacaauc cuacuccauc augugcauca uuaaagaaga aguccucgca      900

uacguagucc agcucccccu cuacggcguc auagacaccc ccugcuggaa acuacacaca      960

ucaccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgaggcuggu acugcgauaa cgccggcagc gucuccuucu ucccccaagc agaaaccugc     1080

aagguccaau ccaaccgagu uuucugcgac acuaugaacu cgcucacccu ccccuccgaa     1140

gucaaccucu gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucc     1200

aagaccgacg uauccuccuc cgucaucacc ucccuaggcg ccauaguaag uugcuacggc     1260

aaaaccaagu gcacagcaag caacaaaaac cgaggaauaa ucaaaaccuu cuccaacggc     1320

ugcgacuacg uauccaacaa gggcgucgac accguauccg uagggaacac ccuuuacugc     1380

guaaacaaac aagaaggaca aucacucuac guaaaaggcg aacccauaau caacuucuac     1440

gacccccucg uauuucccuc cgacgaauuu gacgcaucaa ucucacaggu caacgaaaaa     1500

auaaaccaau cgcuagcauu caucagaaaa ucagacgaac uccuacacaa cgucaacgca     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgucauaau cgucauacua     1620

cucucacuca uagcagucgg ccuccuccua uacuguaaag caaggucgac cccagucacc     1680

cuauccaaag accaacuaag cggcaucaac aacaucgcgu ucucaaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  1837
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1837
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1838
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1838
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1839
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1839
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1840
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1840
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagacc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1841
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1841
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1842
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1842
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagacc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1843
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1843
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuaaa agcaaacgcu      120

auaacaacaa uacuaacagc agucacauuc ugcuuugcau caggccaaaa caucacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucgaaaggau accuaggcgc auuaagaacc      240

ggaugguaua caucagucau aacaauugaa cuaucuaaca uaaaagaaaa caaauguaac      300

ggcacagaug ccaaaguaaa acucaucaaa caagaauuag auaaauacaa aaacgcaguc      360

acugaacuac aacucuuaau gcaaucaaca ccugcaacag gaucaggauc agcaauaugc      420

ucaggaguag ccguauguaa aguacuacac cuagaaggag aagucaacaa aauaaaauca      480

gcccuccuaa guacaaacaa agcugucgua ucacuaucca augguguuuc aguacuaacu      540

uucaaaguuc uagaccuaaa aaacuacaua gacaaacaac uacuaccaau acuaaauaaa      600

caaaguuguu cuauacccaa cauagaaacc gucauagaau uucaacaaaa aaauaauaga      660

cuccuagaaa uaacaagaga auuuucaguu aacgcaggug uaacaacccc aguauccacc      720

uauaugcuaa caaauucaga auuacuuucc cuaaucaacg acaugcccau aacaaaugac      780

caaaaaaaau uaaugucaaa caacguccaa auaguucguc aacaaucaua uucaauaaug      840

ugcauaauaa aagaagaagu cuuagccuac guaguacaac uuccccuuua uggaguuauc      900

gacacacccu gcuggaaacu ccacacuuca ccacuaugua cuacaaacac aaaagaagga      960

uccaacaucu gccucacaag aaccgaucga ggaugguacu gugauaacgc cggauccguc     1020

ucauucuucc cacaagcaga aacaugcaaa guacaaucaa acagaguauu uugcgacaca     1080

augaacuccc ucacauuacc uucugaagua aaccuaugua auguagacau auucaacccc     1140

aaauacgauu gcaaaauaau gacaucaaag acagauguau caucaagugu caucacaucc     1200

cuaggagcaa uugucucaug uuaugguaaa acaaaaugca ccgcaucaaa uaaaaacaga     1260

ggcauaauaa aaaccuucuc aaacgguugu gacuacguau ccaauaaagg cgucgacaca     1320

guaucaguag guaacacauu auauugugua aacaaacaag aaggacaguc ccuauaugua     1380

aaaggagaac caauaaucaa cuucuacgac ccacuuguuu ucccuucuga ugaauuugac     1440

gcaaguauau cacaaguaaa ugaaaaaauc aaucaaucac uagccuuuau aagaaaauca     1500

gaugaauuau uacacaacgu aaacgccgga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaaucg ucauaauagu cauccuacua ucacucauag caguuggacu ccuacuauac     1620

ugcaaagcac gaucaacacc aguaacauua uccaaagacc aacuaagugg uaucaauaac     1680

aucgccuuuu caaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1844
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1844
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauccucaa agccaacgca      120

aucaccacaa uccucacugc cgucaccuuc ugcuucgccu ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaaccug uucagcgguc uccaaaggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgugau caccauagaa cucuccaaca ucaaggaaaa caaaugcaac      300

ggcaccgacg cgaaggucaa acuuauuaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacuac aacuccuaau gcaguccacg ccagccaccg gcucuggcuc agccauaugc      420

uccggugugg ccguaugcaa aguccuacac cucgaaggag aagucaacaa aauaaaaucc      480

gcccuacugu ccacaaacaa ggccguaguc ucccucucaa acggcgucuc aguacucacc      540

uucaaagucc uagaccucaa gaacuacauc gacaaacaac uccuacccau acuaaacaaa      600

caauccugcu caauccccaa caucgaaacc guaauagaau uucaacaaaa aaacaacaga      660

cuccuggaga ucacccggga auuuuccgua aacgccggag ucacaacacc cgucucaacc      720

uacaugcuaa cgaacucaga gcuccucuca cuuaucaacg acaugcccau aacaaacgac      780

caaaaaaaac ucauguccaa caacgugcaa aucguccgac aacaauccua cuccaucaug      840

ugcaucauua aagaagaagu ccucgcauac guaguccagc ucccccucua cggcgucaua      900

gacacccccu gcuggaaacu acacacauca ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg caccgaccga ggcugguacu gcgauaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccugcaag guccaaucca accgaguuuu cugcgacacu     1080

augaacucgc ucacccuccc cuccgaaguc aaccucugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaag accgacguau ccuccuccgu caucaccucc     1200

cuaggcgcca uaguaaguug cuacggcaaa accaagugca cagcaagcaa caaaaaccga     1260

ggaauaauca aaaccuucuc caacggcugc gacuacguau ccaacaaggg cgucgacacc     1320

guauccguag ggaacacccu uuacugcgua aacaaacaag aaggacaauc acucuacgua     1380

aaaggcgaac ccauaaucaa cuucuacgac ccccucguau uucccuccga cgaauuugac     1440

gcaucaaucu cacaggucaa cgaaaaaaua aaccaaucgc uagcauucau cagaaaauca     1500

gacgaacucc uacacaacgu caacgcaggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ucauaaucgu cauacuacuc ucacucauag cagucggccu ccuccuauac     1620

uguaaagcaa ggucgacccc agucacccua uccaaagacc aacuaagcgg caucaacaac     1680

aucgcguucu caaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  1845
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1845
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1846
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1846
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1847
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1847
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1848
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1848
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagacc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1849
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1849
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1850
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1850
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagacc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1851
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1851
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuaaa agcaaacgcu      120

auaacaacaa uacuaacagc agucacauuc ugcuuugcau caggccaaaa caucacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucgaaaggau accuaggcgc auuaagaacc      240

ggaugguaua caucagucau aacaauugaa cuaucuaaca uaaaagaaaa caaauguaac      300

ggcacagaug ccaaaguaaa acucaucaaa caagaauuag auaaauacaa aaacgcaguc      360

acugaacuac aacucuuaau gcaaucaaca ccugcaacag gaucaggauc agcaauaugc      420

ucaggaguag ccguauguaa aguacuacac cuagaaggag aagucaacaa aauaaaauca      480

gcccuccuaa guacaaacaa agcugucgua ucacuaucca augguguuuc aguacuaacu      540

uucaaaguuc uagaccuaaa aaacuacaua gacaaacaac uacuaccaau acuaaauaaa      600

caaaguuguu cuauacccaa cauagaaacc gucauagaau uucaacaaaa aaauaauaga      660

cuccuagaaa uaacaagaga auuuucaguu aacgcaggug uaacaacccc aguauccacc      720

uauaugcuaa caaauucaga auuacuuucc cuaaucaacg acaugcccau aacaaaugac      780

caaaaaaaau uaaugucaaa caacguccaa auaguucguc aacaaucaua uucaauaaug      840

ugcauaauaa aagaagaagu cuuagccuac guaguacaac uuccccuuua uggaguuauc      900

gacacacccu gcuggaaacu ccacacuuca ccacuaugua cuacaaacac aaaagaagga      960

uccaacaucu gccucacaag aaccgaucga ggaugguacu gugauaacgc cggauccguc     1020

ucauucuucc cacaagcaga aacaugcaaa guacaaucaa acagaguauu uugcgacaca     1080

augaacuccc ucacauuacc uucugaagua aaccuaugua auguagacau auucaacccc     1140

aaauacgauu gcaaaauaau gacaucaaag acagauguau caucaagugu caucacaucc     1200

cuaggagcaa uugucucaug uuaugguaaa acaaaaugca ccgcaucaaa uaaaaacaga     1260

ggcauaauaa aaaccuucuc aaacgguugu gacuacguau ccaauaaagg cgucgacaca     1320

guaucaguag guaacacauu auauugugua aacaaacaag aaggacaguc ccuauaugua     1380

aaaggagaac caauaaucaa cuucuacgac ccacuuguuu ucccuucuga ugaauuugac     1440

gcaaguauau cacaaguaaa ugaaaaaauc aaucaaucac uagccuuuau aagaaaauca     1500

gaugaauuau uacacaacgu aaacgccgga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaaucg ucauaauagu cauccuacua ucacucauag caguuggacu ccuacuauac     1620

ugcaaagcac gaucaacacc aguaacauua uccaaagacc aacuaagugg uaucaauaac     1680

aucgccuuuu caaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1852
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1852
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauccucaa agccaacgca      120

aucaccacaa uccucacugc cgucaccuuc ugcuucgccu ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaaccug uucagcgguc uccaaaggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgugau caccauagaa cucuccaaca ucaaggaaaa caaaugcaac      300

ggcaccgacg cgaaggucaa acuuauuaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacuac aacuccuaau gcaguccacg ccagccaccg gcucuggcuc agccauaugc      420

uccggugugg ccguaugcaa aguccuacac cucgaaggag aagucaacaa aauaaaaucc      480

gcccuacugu ccacaaacaa ggccguaguc ucccucucaa acggcgucuc aguacucacc      540

uucaaagucc uagaccucaa gaacuacauc gacaaacaac uccuacccau acuaaacaaa      600

caauccugcu caauccccaa caucgaaacc guaauagaau uucaacaaaa aaacaacaga      660

cuccuggaga ucacccggga auuuuccgua aacgccggag ucacaacacc cgucucaacc      720

uacaugcuaa cgaacucaga gcuccucuca cuuaucaacg acaugcccau aacaaacgac      780

caaaaaaaac ucauguccaa caacgugcaa aucguccgac aacaauccua cuccaucaug      840

ugcaucauua aagaagaagu ccucgcauac guaguccagc ucccccucua cggcgucaua      900

gacacccccu gcuggaaacu acacacauca ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg caccgaccga ggcugguacu gcgauaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccugcaag guccaaucca accgaguuuu cugcgacacu     1080

augaacucgc ucacccuccc cuccgaaguc aaccucugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaag accgacguau ccuccuccgu caucaccucc     1200

cuaggcgcca uaguaaguug cuacggcaaa accaagugca cagcaagcaa caaaaaccga     1260

ggaauaauca aaaccuucuc caacggcugc gacuacguau ccaacaaggg cgucgacacc     1320

guauccguag ggaacacccu uuacugcgua aacaaacaag aaggacaauc acucuacgua     1380

aaaggcgaac ccauaaucaa cuucuacgac ccccucguau uucccuccga cgaauuugac     1440

gcaucaaucu cacaggucaa cgaaaaaaua aaccaaucgc uagcauucau cagaaaauca     1500

gacgaacucc uacacaacgu caacgcaggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ucauaaucgu cauacuacuc ucacucauag cagucggccu ccuccuauac     1620

uguaaagcaa ggucgacccc agucacccua uccaaagacc aacuaagcgg caucaacaac     1680

aucgcguucu caaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  1853
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1853
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1854
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1854
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1855
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1855
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1856
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1856
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagacc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1857
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1857
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1858
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1858
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagacc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1859
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1859
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuaaa agcaaacgcu      120

auaacaacaa uacuaacagc agucacauuc ugcuuugcau caggccaaaa caucacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucgaaaggau accuaggcgc auuaagaacc      240

ggaugguaua caucagucau aacaauugaa cuaucuaaca uaaaagaaaa caaauguaac      300

ggcacagaug ccaaaguaaa acucaucaaa caagaauuag auaaauacaa aaacgcaguc      360

acugaacuac aacucuuaau gcaaucaaca ccugcaacag gaucaggauc agcaauaugc      420

ucaggaguag ccguauguaa aguacuacac cuagaaggag aagucaacaa aauaaaauca      480

gcccuccuaa guacaaacaa agcugucgua ucacuaucca augguguuuc aguacuaacu      540

uucaaaguuc uagaccuaaa aaacuacaua gacaaacaac uacuaccaau acuaaauaaa      600

caaaguuguu cuauacccaa cauagaaacc gucauagaau uucaacaaaa aaauaauaga      660

cuccuagaaa uaacaagaga auuuucaguu aacgcaggug uaacaacccc aguauccacc      720

uauaugcuaa caaauucaga auuacuuucc cuaaucaacg acaugcccau aacaaaugac      780

caaaaaaaau uaaugucaaa caacguccaa auaguucguc aacaaucaua uucaauaaug      840

ugcauaauaa aagaagaagu cuuagccuac guaguacaac uuccccuuua uggaguuauc      900

gacacacccu gcuggaaacu ccacacuuca ccacuaugua cuacaaacac aaaagaagga      960

uccaacaucu gccucacaag aaccgaucga ggaugguacu gugauaacgc cggauccguc     1020

ucauucuucc cacaagcaga aacaugcaaa guacaaucaa acagaguauu uugcgacaca     1080

augaacuccc ucacauuacc uucugaagua aaccuaugua auguagacau auucaacccc     1140

aaauacgauu gcaaaauaau gacaucaaag acagauguau caucaagugu caucacaucc     1200

cuaggagcaa uugucucaug uuaugguaaa acaaaaugca ccgcaucaaa uaaaaacaga     1260

ggcauaauaa aaaccuucuc aaacgguugu gacuacguau ccaauaaagg cgucgacaca     1320

guaucaguag guaacacauu auauugugua aacaaacaag aaggacaguc ccuauaugua     1380

aaaggagaac caauaaucaa cuucuacgac ccacuuguuu ucccuucuga ugaauuugac     1440

gcaaguauau cacaaguaaa ugaaaaaauc aaucaaucac uagccuuuau aagaaaauca     1500

gaugaauuau uacacaacgu aaacgccgga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaaucg ucauaauagu cauccuacua ucacucauag caguuggacu ccuacuauac     1620

ugcaaagcac gaucaacacc aguaacauua uccaaagacc aacuaagugg uaucaauaac     1680

aucgccuuuu caaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1860
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1860
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauccucaa agccaacgca      120

aucaccacaa uccucacugc cgucaccuuc ugcuucgccu ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaaccug uucagcgguc uccaaaggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgugau caccauagaa cucuccaaca ucaaggaaaa caaaugcaac      300

ggcaccgacg cgaaggucaa acuuauuaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacuac aacuccuaau gcaguccacg ccagccaccg gcucuggcuc agccauaugc      420

uccggugugg ccguaugcaa aguccuacac cucgaaggag aagucaacaa aauaaaaucc      480

gcccuacugu ccacaaacaa ggccguaguc ucccucucaa acggcgucuc aguacucacc      540

uucaaagucc uagaccucaa gaacuacauc gacaaacaac uccuacccau acuaaacaaa      600

caauccugcu caauccccaa caucgaaacc guaauagaau uucaacaaaa aaacaacaga      660

cuccuggaga ucacccggga auuuuccgua aacgccggag ucacaacacc cgucucaacc      720

uacaugcuaa cgaacucaga gcuccucuca cuuaucaacg acaugcccau aacaaacgac      780

caaaaaaaac ucauguccaa caacgugcaa aucguccgac aacaauccua cuccaucaug      840

ugcaucauua aagaagaagu ccucgcauac guaguccagc ucccccucua cggcgucaua      900

gacacccccu gcuggaaacu acacacauca ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg caccgaccga ggcugguacu gcgauaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccugcaag guccaaucca accgaguuuu cugcgacacu     1080

augaacucgc ucacccuccc cuccgaaguc aaccucugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaag accgacguau ccuccuccgu caucaccucc     1200

cuaggcgcca uaguaaguug cuacggcaaa accaagugca cagcaagcaa caaaaaccga     1260

ggaauaauca aaaccuucuc caacggcugc gacuacguau ccaacaaggg cgucgacacc     1320

guauccguag ggaacacccu uuacugcgua aacaaacaag aaggacaauc acucuacgua     1380

aaaggcgaac ccauaaucaa cuucuacgac ccccucguau uucccuccga cgaauuugac     1440

gcaucaaucu cacaggucaa cgaaaaaaua aaccaaucgc uagcauucau cagaaaauca     1500

gacgaacucc uacacaacgu caacgcaggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ucauaaucgu cauacuacuc ucacucauag cagucggccu ccuccuauac     1620

uguaaagcaa ggucgacccc agucacccua uccaaagacc aacuaagcgg caucaacaac     1680

aucgcguucu caaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  1861
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1861
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1862
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1862
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1863
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1863
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1864
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1864
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagacc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1865
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1865
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1866
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1866
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagacc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1867
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1867
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuaaa agcaaacgcu      120

auaacaacaa uacuaacagc agucacauuc ugcuuugcau caggccaaaa caucacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucgaaaggau accuaggcgc auuaagaacc      240

ggaugguaua caucagucau aacaauugaa cuaucuaaca uaaaagaaaa caaauguaac      300

ggcacagaug ccaaaguaaa acucaucaaa caagaauuag auaaauacaa aaacgcaguc      360

acugaacuac aacucuuaau gcaaucaaca ccugcaacag gaucaggauc agcaauaugc      420

ucaggaguag ccguauguaa aguacuacac cuagaaggag aagucaacaa aauaaaauca      480

gcccuccuaa guacaaacaa agcugucgua ucacuaucca augguguuuc aguacuaacu      540

uucaaaguuc uagaccuaaa aaacuacaua gacaaacaac uacuaccaau acuaaauaaa      600

caaaguuguu cuauacccaa cauagaaacc gucauagaau uucaacaaaa aaauaauaga      660

cuccuagaaa uaacaagaga auuuucaguu aacgcaggug uaacaacccc aguauccacc      720

uauaugcuaa caaauucaga auuacuuucc cuaaucaacg acaugcccau aacaaaugac      780

caaaaaaaau uaaugucaaa caacguccaa auaguucguc aacaaucaua uucaauaaug      840

ugcauaauaa aagaagaagu cuuagccuac guaguacaac uuccccuuua uggaguuauc      900

gacacacccu gcuggaaacu ccacacuuca ccacuaugua cuacaaacac aaaagaagga      960

uccaacaucu gccucacaag aaccgaucga ggaugguacu gugauaacgc cggauccguc     1020

ucauucuucc cacaagcaga aacaugcaaa guacaaucaa acagaguauu uugcgacaca     1080

augaacuccc ucacauuacc uucugaagua aaccuaugua auguagacau auucaacccc     1140

aaauacgauu gcaaaauaau gacaucaaag acagauguau caucaagugu caucacaucc     1200

cuaggagcaa uugucucaug uuaugguaaa acaaaaugca ccgcaucaaa uaaaaacaga     1260

ggcauaauaa aaaccuucuc aaacgguugu gacuacguau ccaauaaagg cgucgacaca     1320

guaucaguag guaacacauu auauugugua aacaaacaag aaggacaguc ccuauaugua     1380

aaaggagaac caauaaucaa cuucuacgac ccacuuguuu ucccuucuga ugaauuugac     1440

gcaaguauau cacaaguaaa ugaaaaaauc aaucaaucac uagccuuuau aagaaaauca     1500

gaugaauuau uacacaacgu aaacgccgga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaaucg ucauaauagu cauccuacua ucacucauag caguuggacu ccuacuauac     1620

ugcaaagcac gaucaacacc aguaacauua uccaaagacc aacuaagugg uaucaauaac     1680

aucgccuuuu caaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1868
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1868
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauccucaa agccaacgca      120

aucaccacaa uccucacugc cgucaccuuc ugcuucgccu ccggccaaaa cauaacagaa      180

gaauuuuacc aaucaaccug uucagcgguc uccaaaggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgugau caccauagaa cucuccaaca ucaaggaaaa caaaugcaac      300

ggcaccgacg cgaaggucaa acuuauuaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaacuac aacuccuaau gcaguccacg ccagccaccg gcucuggcuc agccauaugc      420

uccggugugg ccguaugcaa aguccuacac cucgaaggag aagucaacaa aauaaaaucc      480

gcccuacugu ccacaaacaa ggccguaguc ucccucucaa acggcgucuc aguacucacc      540

uucaaagucc uagaccucaa gaacuacauc gacaaacaac uccuacccau acuaaacaaa      600

caauccugcu caauccccaa caucgaaacc guaauagaau uucaacaaaa aaacaacaga      660

cuccuggaga ucacccggga auuuuccgua aacgccggag ucacaacacc cgucucaacc      720

uacaugcuaa cgaacucaga gcuccucuca cuuaucaacg acaugcccau aacaaacgac      780

caaaaaaaac ucauguccaa caacgugcaa aucguccgac aacaauccua cuccaucaug      840

ugcaucauua aagaagaagu ccucgcauac guaguccagc ucccccucua cggcgucaua      900

gacacccccu gcuggaaacu acacacauca ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg caccgaccga ggcugguacu gcgauaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccugcaag guccaaucca accgaguuuu cugcgacacu     1080

augaacucgc ucacccuccc cuccgaaguc aaccucugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaag accgacguau ccuccuccgu caucaccucc     1200

cuaggcgcca uaguaaguug cuacggcaaa accaagugca cagcaagcaa caaaaaccga     1260

ggaauaauca aaaccuucuc caacggcugc gacuacguau ccaacaaggg cgucgacacc     1320

guauccguag ggaacacccu uuacugcgua aacaaacaag aaggacaauc acucuacgua     1380

aaaggcgaac ccauaaucaa cuucuacgac ccccucguau uucccuccga cgaauuugac     1440

gcaucaaucu cacaggucaa cgaaaaaaua aaccaaucgc uagcauucau cagaaaauca     1500

gacgaacucc uacacaacgu caacgcaggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ucauaaucgu cauacuacuc ucacucauag cagucggccu ccuccuauac     1620

uguaaagcaa ggucgacccc agucacccua uccaaagacc aacuaagcgg caucaacaac     1680

aucgcguucu caaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  1869
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1869
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1870
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1870
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1871
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1871
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1872
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1872
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaccaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1873
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1873
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1874
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1874
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaccaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1875
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1875
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac      120

uaacagcagu cacauucugc uuugcaucag gccaaaacau cacagaagaa uuuuaccaau      180

caacaugcuc cgccguaucg aaaggauacc uaggcgcauu aagaaccgga ugguauacau      240

cagucauaac aauugaacua ucuaacauaa aagaaaacaa auguaacggc acagaugcca      300

aaguaaaacu caucaaacaa gaauuagaua aauacaaaaa cgcagucacu gaacuacaac      360

ucuuaaugca aucaacaccu gcaacaggau caggaucagc aauaugcuca ggaguagccg      420

uauguaaagu acuacaccua gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua      480

caaacaaagc ugucguauca cuauccaaug guguuucagu acuaacuuuc aaaguucuag      540

accuaaaaaa cuacauagac aaacaacuac uaccaauacu aaauaaacaa aguuguucua      600

uacccaacau agaaaccguc auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa      660

caagagaauu uucaguuaac gcagguguaa caaccccagu auccaccuau augcuaacaa      720

auucagaauu acuuucccua aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa      780

ugucaaacaa cguccaaaua guucgucaac aaucauauuc aauaaugugc auaauaaaag      840

aagaagucuu agccuacgua guacaacuuc cccuuuaugg aguuaucgac acacccugcu      900

ggaaacucca cacuucacca cuauguacua caaacacaaa agaaggaucc aacaucugcc      960

ucacaagaac cgaucgagga ugguacugug auaacgccgg auccgucuca uucuucccac     1020

aagcagaaac augcaaagua caaucaaaca gaguauuuug cgacacaaug aacucccuca     1080

cauuaccuuc ugaaguaaac cuauguaaug uagacauauu caaccccaaa uacgauugca     1140

aaauaaugac aucaaagaca gauguaucau caagugucau cacaucccua ggagcaauug     1200

ucucauguua ugguaaaaca aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa     1260

ccuucucaaa cgguugugac uacguaucca auaaaggcgu cgacacagua ucaguaggua     1320

acacauuaua uuguguaaac aaacaagaag gacagucccu auauguaaaa ggagaaccaa     1380

uaaucaacuu cuacgaccca cuuguuuucc cuucugauga auuugacgca aguauaucac     1440

aaguaaauga aaaaaucaau caaucacuag ccuuuauaag aaaaucagau gaauuauuac     1500

acaacguaaa cgccggaaaa ucaacaacca acauaaugau aaccacaaua auaaucguca     1560

uaauagucau ccuacuauca cucauagcag uuggacuccu acuauacugc aaagcacgau     1620

caacaccagu aacauuaucc aaagaccaac uaagugguau caauaacauc gccuuuucaa     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1876
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1876
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uccucaaagc caacgcaauc accacaaucc      120

ucacugccgu caccuucugc uucgccuccg gccaaaacau aacagaagaa uuuuaccaau      180

caaccuguuc agcggucucc aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgugaucac cauagaacuc uccaacauca aggaaaacaa augcaacggc accgacgcga      300

aggucaaacu uauuaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuacaac      360

uccuaaugca guccacgcca gccaccggcu cuggcucagc cauaugcucc gguguggccg      420

uaugcaaagu ccuacaccuc gaaggagaag ucaacaaaau aaaauccgcc cuacugucca      480

caaacaaggc cguagucucc cucucaaacg gcgucucagu acucaccuuc aaaguccuag      540

accucaagaa cuacaucgac aaacaacucc uacccauacu aaacaaacaa uccugcucaa      600

uccccaacau cgaaaccgua auagaauuuc aacaaaaaaa caacagacuc cuggagauca      660

cccgggaauu uuccguaaac gccggaguca caacacccgu cucaaccuac augcuaacga      720

acucagagcu ccucucacuu aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

uguccaacaa cgugcaaauc guccgacaac aauccuacuc caucaugugc aucauuaaag      840

aagaaguccu cgcauacgua guccagcucc cccucuacgg cgucauagac acccccugcu      900

ggaaacuaca cacaucaccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccgcac cgaccgaggc ugguacugcg auaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cugcaagguc caauccaacc gaguuuucug cgacacuaug aacucgcuca     1080

cccuccccuc cgaagucaac cucugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cuccaagacc gacguauccu ccuccgucau caccucccua ggcgccauag     1200

uaaguugcua cggcaaaacc aagugcacag caagcaacaa aaaccgagga auaaucaaaa     1260

ccuucuccaa cggcugcgac uacguaucca acaagggcgu cgacaccgua uccguaggga     1320

acacccuuua cugcguaaac aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca     1380

uaaucaacuu cuacgacccc cucguauuuc ccuccgacga auuugacgca ucaaucucac     1440

aggucaacga aaaaauaaac caaucgcuag cauucaucag aaaaucagac gaacuccuac     1500

acaacgucaa cgcaggcaag agcaccacca acaucaugau caccaccauc aucaucguca     1560

uaaucgucau acuacucuca cucauagcag ucggccuccu ccuauacugu aaagcaaggu     1620

cgaccccagu cacccuaucc aaagaccaac uaagcggcau caacaacauc gcguucucaa     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  1877
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1877
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1878
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1878
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1879
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1879
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1880
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1880
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaccaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1881
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1881
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1882
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1882
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaccaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1883
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1883
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac      120

uaacagcagu cacauucugc uuugcaucag gccaaaacau cacagaagaa uuuuaccaau      180

caacaugcuc cgccguaucg aaaggauacc uaggcgcauu aagaaccgga ugguauacau      240

cagucauaac aauugaacua ucuaacauaa aagaaaacaa auguaacggc acagaugcca      300

aaguaaaacu caucaaacaa gaauuagaua aauacaaaaa cgcagucacu gaacuacaac      360

ucuuaaugca aucaacaccu gcaacaggau caggaucagc aauaugcuca ggaguagccg      420

uauguaaagu acuacaccua gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua      480

caaacaaagc ugucguauca cuauccaaug guguuucagu acuaacuuuc aaaguucuag      540

accuaaaaaa cuacauagac aaacaacuac uaccaauacu aaauaaacaa aguuguucua      600

uacccaacau agaaaccguc auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa      660

caagagaauu uucaguuaac gcagguguaa caaccccagu auccaccuau augcuaacaa      720

auucagaauu acuuucccua aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa      780

ugucaaacaa cguccaaaua guucgucaac aaucauauuc aauaaugugc auaauaaaag      840

aagaagucuu agccuacgua guacaacuuc cccuuuaugg aguuaucgac acacccugcu      900

ggaaacucca cacuucacca cuauguacua caaacacaaa agaaggaucc aacaucugcc      960

ucacaagaac cgaucgagga ugguacugug auaacgccgg auccgucuca uucuucccac     1020

aagcagaaac augcaaagua caaucaaaca gaguauuuug cgacacaaug aacucccuca     1080

cauuaccuuc ugaaguaaac cuauguaaug uagacauauu caaccccaaa uacgauugca     1140

aaauaaugac aucaaagaca gauguaucau caagugucau cacaucccua ggagcaauug     1200

ucucauguua ugguaaaaca aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa     1260

ccuucucaaa cgguugugac uacguaucca auaaaggcgu cgacacagua ucaguaggua     1320

acacauuaua uuguguaaac aaacaagaag gacagucccu auauguaaaa ggagaaccaa     1380

uaaucaacuu cuacgaccca cuuguuuucc cuucugauga auuugacgca aguauaucac     1440

aaguaaauga aaaaaucaau caaucacuag ccuuuauaag aaaaucagau gaauuauuac     1500

acaacguaaa cgccggaaaa ucaacaacca acauaaugau aaccacaaua auaaucguca     1560

uaauagucau ccuacuauca cucauagcag uuggacuccu acuauacugc aaagcacgau     1620

caacaccagu aacauuaucc aaagaccaac uaagugguau caauaacauc gccuuuucaa     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1884
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1884
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uccucaaagc caacgcaauc accacaaucc      120

ucacugccgu caccuucugc uucgccuccg gccaaaacau aacagaagaa uuuuaccaau      180

caaccuguuc agcggucucc aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgugaucac cauagaacuc uccaacauca aggaaaacaa augcaacggc accgacgcga      300

aggucaaacu uauuaaacaa gaacucgaca aauacaaaaa cgcagucacc gaacuacaac      360

uccuaaugca guccacgcca gccaccggcu cuggcucagc cauaugcucc gguguggccg      420

uaugcaaagu ccuacaccuc gaaggagaag ucaacaaaau aaaauccgcc cuacugucca      480

caaacaaggc cguagucucc cucucaaacg gcgucucagu acucaccuuc aaaguccuag      540

accucaagaa cuacaucgac aaacaacucc uacccauacu aaacaaacaa uccugcucaa      600

uccccaacau cgaaaccgua auagaauuuc aacaaaaaaa caacagacuc cuggagauca      660

cccgggaauu uuccguaaac gccggaguca caacacccgu cucaaccuac augcuaacga      720

acucagagcu ccucucacuu aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

uguccaacaa cgugcaaauc guccgacaac aauccuacuc caucaugugc aucauuaaag      840

aagaaguccu cgcauacgua guccagcucc cccucuacgg cgucauagac acccccugcu      900

ggaaacuaca cacaucaccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccgcac cgaccgaggc ugguacugcg auaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cugcaagguc caauccaacc gaguuuucug cgacacuaug aacucgcuca     1080

cccuccccuc cgaagucaac cucugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cuccaagacc gacguauccu ccuccgucau caccucccua ggcgccauag     1200

uaaguugcua cggcaaaacc aagugcacag caagcaacaa aaaccgagga auaaucaaaa     1260

ccuucuccaa cggcugcgac uacguaucca acaagggcgu cgacaccgua uccguaggga     1320

acacccuuua cugcguaaac aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca     1380

uaaucaacuu cuacgacccc cucguauuuc ccuccgacga auuugacgca ucaaucucac     1440

aggucaacga aaaaauaaac caaucgcuag cauucaucag aaaaucagac gaacuccuac     1500

acaacgucaa cgcaggcaag agcaccacca acaucaugau caccaccauc aucaucguca     1560

uaaucgucau acuacucuca cucauagcag ucggccuccu ccuauacugu aaagcaaggu     1620

cgaccccagu cacccuaucc aaagaccaac uaagcggcau caacaacauc gcguucucaa     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  1885
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1885
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1886
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1886
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1887
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1887
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1888
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1888
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagacca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1889
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1889
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1890
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1890
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagacca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1891
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1891
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuaaaa gcaaacgcua uaacaacaau acuaacagca      120

gucacauucu gcuuugcauc aggccaaaac aucacagaag aauuuuacca aucaacaugc      180

uccgccguau cgaaaggaua ccuaggcgca uuaagaaccg gaugguauac aucagucaua      240

acaauugaac uaucuaacau aaaagaaaac aaauguaacg gcacagaugc caaaguaaaa      300

cucaucaaac aagaauuaga uaaauacaaa aacgcaguca cugaacuaca acucuuaaug      360

caaucaacac cugcaacagg aucaggauca gcaauaugcu caggaguagc cguauguaaa      420

guacuacacc uagaaggaga agucaacaaa auaaaaucag cccuccuaag uacaaacaaa      480

gcugucguau cacuauccaa ugguguuuca guacuaacuu ucaaaguucu agaccuaaaa      540

aacuacauag acaaacaacu acuaccaaua cuaaauaaac aaaguuguuc uauacccaac      600

auagaaaccg ucauagaauu ucaacaaaaa aauaauagac uccuagaaau aacaagagaa      660

uuuucaguua acgcaggugu aacaacccca guauccaccu auaugcuaac aaauucagaa      720

uuacuuuccc uaaucaacga caugcccaua acaaaugacc aaaaaaaauu aaugucaaac      780

aacguccaaa uaguucguca acaaucauau ucaauaaugu gcauaauaaa agaagaaguc      840

uuagccuacg uaguacaacu uccccuuuau ggaguuaucg acacacccug cuggaaacuc      900

cacacuucac cacuauguac uacaaacaca aaagaaggau ccaacaucug ccucacaaga      960

accgaucgag gaugguacug ugauaacgcc ggauccgucu cauucuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa cagaguauuu ugcgacacaa ugaacucccu cacauuaccu     1080

ucugaaguaa accuauguaa uguagacaua uucaacccca aauacgauug caaaauaaug     1140

acaucaaaga cagauguauc aucaaguguc aucacauccc uaggagcaau ugucucaugu     1200

uaugguaaaa caaaaugcac cgcaucaaau aaaaacagag gcauaauaaa aaccuucuca     1260

aacgguugug acuacguauc caauaaaggc gucgacacag uaucaguagg uaacacauua     1320

uauuguguaa acaaacaaga aggacagucc cuauauguaa aaggagaacc aauaaucaac     1380

uucuacgacc cacuuguuuu cccuucugau gaauuugacg caaguauauc acaaguaaau     1440

gaaaaaauca aucaaucacu agccuuuaua agaaaaucag augaauuauu acacaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaaccacaa uaauaaucgu cauaauaguc     1560

auccuacuau cacucauagc aguuggacuc cuacuauacu gcaaagcacg aucaacacca     1620

guaacauuau ccaaagacca acuaaguggu aucaauaaca ucgccuuuuc aaacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1892
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1892
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauccucaaa gccaacgcaa ucaccacaau ccucacugcc      120

gucaccuucu gcuucgccuc cggccaaaac auaacagaag aauuuuacca aucaaccugu      180

ucagcggucu ccaaaggcua ccucggcgcc cuccgcaccg gcugguacac cuccgugauc      240

accauagaac ucuccaacau caaggaaaac aaaugcaacg gcaccgacgc gaaggucaaa      300

cuuauuaaac aagaacucga caaauacaaa aacgcaguca ccgaacuaca acuccuaaug      360

caguccacgc cagccaccgg cucuggcuca gccauaugcu ccgguguggc cguaugcaaa      420

guccuacacc ucgaaggaga agucaacaaa auaaaauccg cccuacuguc cacaaacaag      480

gccguagucu cccucucaaa cggcgucuca guacucaccu ucaaaguccu agaccucaag      540

aacuacaucg acaaacaacu ccuacccaua cuaaacaaac aauccugcuc aauccccaac      600

aucgaaaccg uaauagaauu ucaacaaaaa aacaacagac uccuggagau cacccgggaa      660

uuuuccguaa acgccggagu cacaacaccc gucucaaccu acaugcuaac gaacucagag      720

cuccucucac uuaucaacga caugcccaua acaaacgacc aaaaaaaacu cauguccaac      780

aacgugcaaa ucguccgaca acaauccuac uccaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg uaguccagcu cccccucuac ggcgucauag acacccccug cuggaaacua      900

cacacaucac cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgc      960

accgaccgag gcugguacug cgauaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accugcaagg uccaauccaa ccgaguuuuc ugcgacacua ugaacucgcu cacccucccc     1080

uccgaaguca accucugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accuccaaga ccgacguauc cuccuccguc aucaccuccc uaggcgccau aguaaguugc     1200

uacggcaaaa ccaagugcac agcaagcaac aaaaaccgag gaauaaucaa aaccuucucc     1260

aacggcugcg acuacguauc caacaagggc gucgacaccg uauccguagg gaacacccuu     1320

uacugcguaa acaaacaaga aggacaauca cucuacguaa aaggcgaacc cauaaucaac     1380

uucuacgacc cccucguauu ucccuccgac gaauuugacg caucaaucuc acaggucaac     1440

gaaaaaauaa accaaucgcu agcauucauc agaaaaucag acgaacuccu acacaacguc     1500

aacgcaggca agagcaccac caacaucaug aucaccacca ucaucaucgu cauaaucguc     1560

auacuacucu cacucauagc agucggccuc cuccuauacu guaaagcaag gucgacccca     1620

gucacccuau ccaaagacca acuaagcggc aucaacaaca ucgcguucuc aaacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  1893
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1893
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1894
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1894
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1895
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1895
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1896
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1896
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagacca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1897
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1897
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1898
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1898
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagacca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1899
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1899
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuaaaa gcaaacgcua uaacaacaau acuaacagca      120

gucacauucu gcuuugcauc aggccaaaac aucacagaag aauuuuacca aucaacaugc      180

uccgccguau cgaaaggaua ccuaggcgca uuaagaaccg gaugguauac aucagucaua      240

acaauugaac uaucuaacau aaaagaaaac aaauguaacg gcacagaugc caaaguaaaa      300

cucaucaaac aagaauuaga uaaauacaaa aacgcaguca cugaacuaca acucuuaaug      360

caaucaacac cugcaacagg aucaggauca gcaauaugcu caggaguagc cguauguaaa      420

guacuacacc uagaaggaga agucaacaaa auaaaaucag cccuccuaag uacaaacaaa      480

gcugucguau cacuauccaa ugguguuuca guacuaacuu ucaaaguucu agaccuaaaa      540

aacuacauag acaaacaacu acuaccaaua cuaaauaaac aaaguuguuc uauacccaac      600

auagaaaccg ucauagaauu ucaacaaaaa aauaauagac uccuagaaau aacaagagaa      660

uuuucaguua acgcaggugu aacaacccca guauccaccu auaugcuaac aaauucagaa      720

uuacuuuccc uaaucaacga caugcccaua acaaaugacc aaaaaaaauu aaugucaaac      780

aacguccaaa uaguucguca acaaucauau ucaauaaugu gcauaauaaa agaagaaguc      840

uuagccuacg uaguacaacu uccccuuuau ggaguuaucg acacacccug cuggaaacuc      900

cacacuucac cacuauguac uacaaacaca aaagaaggau ccaacaucug ccucacaaga      960

accgaucgag gaugguacug ugauaacgcc ggauccgucu cauucuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa cagaguauuu ugcgacacaa ugaacucccu cacauuaccu     1080

ucugaaguaa accuauguaa uguagacaua uucaacccca aauacgauug caaaauaaug     1140

acaucaaaga cagauguauc aucaaguguc aucacauccc uaggagcaau ugucucaugu     1200

uaugguaaaa caaaaugcac cgcaucaaau aaaaacagag gcauaauaaa aaccuucuca     1260

aacgguugug acuacguauc caauaaaggc gucgacacag uaucaguagg uaacacauua     1320

uauuguguaa acaaacaaga aggacagucc cuauauguaa aaggagaacc aauaaucaac     1380

uucuacgacc cacuuguuuu cccuucugau gaauuugacg caaguauauc acaaguaaau     1440

gaaaaaauca aucaaucacu agccuuuaua agaaaaucag augaauuauu acacaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaaccacaa uaauaaucgu cauaauaguc     1560

auccuacuau cacucauagc aguuggacuc cuacuauacu gcaaagcacg aucaacacca     1620

guaacauuau ccaaagacca acuaaguggu aucaauaaca ucgccuuuuc aaacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1900
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1900
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauccucaaa gccaacgcaa ucaccacaau ccucacugcc      120

gucaccuucu gcuucgccuc cggccaaaac auaacagaag aauuuuacca aucaaccugu      180

ucagcggucu ccaaaggcua ccucggcgcc cuccgcaccg gcugguacac cuccgugauc      240

accauagaac ucuccaacau caaggaaaac aaaugcaacg gcaccgacgc gaaggucaaa      300

cuuauuaaac aagaacucga caaauacaaa aacgcaguca ccgaacuaca acuccuaaug      360

caguccacgc cagccaccgg cucuggcuca gccauaugcu ccgguguggc cguaugcaaa      420

guccuacacc ucgaaggaga agucaacaaa auaaaauccg cccuacuguc cacaaacaag      480

gccguagucu cccucucaaa cggcgucuca guacucaccu ucaaaguccu agaccucaag      540

aacuacaucg acaaacaacu ccuacccaua cuaaacaaac aauccugcuc aauccccaac      600

aucgaaaccg uaauagaauu ucaacaaaaa aacaacagac uccuggagau cacccgggaa      660

uuuuccguaa acgccggagu cacaacaccc gucucaaccu acaugcuaac gaacucagag      720

cuccucucac uuaucaacga caugcccaua acaaacgacc aaaaaaaacu cauguccaac      780

aacgugcaaa ucguccgaca acaauccuac uccaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg uaguccagcu cccccucuac ggcgucauag acacccccug cuggaaacua      900

cacacaucac cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgc      960

accgaccgag gcugguacug cgauaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accugcaagg uccaauccaa ccgaguuuuc ugcgacacua ugaacucgcu cacccucccc     1080

uccgaaguca accucugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accuccaaga ccgacguauc cuccuccguc aucaccuccc uaggcgccau aguaaguugc     1200

uacggcaaaa ccaagugcac agcaagcaac aaaaaccgag gaauaaucaa aaccuucucc     1260

aacggcugcg acuacguauc caacaagggc gucgacaccg uauccguagg gaacacccuu     1320

uacugcguaa acaaacaaga aggacaauca cucuacguaa aaggcgaacc cauaaucaac     1380

uucuacgacc cccucguauu ucccuccgac gaauuugacg caucaaucuc acaggucaac     1440

gaaaaaauaa accaaucgcu agcauucauc agaaaaucag acgaacuccu acacaacguc     1500

aacgcaggca agagcaccac caacaucaug aucaccacca ucaucaucgu cauaaucguc     1560

auacuacucu cacucauagc agucggccuc cuccuauacu guaaagcaag gucgacccca     1620

gucacccuau ccaaagacca acuaagcggc aucaacaaca ucgcguucuc aaacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  1901
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1901
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1902
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1902
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1903
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1903
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1904
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1904
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaccaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1905
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1905
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1906
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1906
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaccaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1907
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1907
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuaaaagca      120

aacgcuauaa caacaauacu aacagcaguc acauucugcu uugcaucagg ccaaaacauc      180

acagaagaau uuuaccaauc aacaugcucc gccguaucga aaggauaccu aggcgcauua      240

agaaccggau gguauacauc agucauaaca auugaacuau cuaacauaaa agaaaacaaa      300

uguaacggca cagaugccaa aguaaaacuc aucaaacaag aauuagauaa auacaaaaac      360

gcagucacug aacuacaacu cuuaaugcaa ucaacaccug caacaggauc aggaucagca      420

auaugcucag gaguagccgu auguaaagua cuacaccuag aaggagaagu caacaaaaua      480

aaaucagccc uccuaaguac aaacaaagcu gucguaucac uauccaaugg uguuucagua      540

cuaacuuuca aaguucuaga ccuaaaaaac uacauagaca aacaacuacu accaauacua      600

aauaaacaaa guuguucuau acccaacaua gaaaccguca uagaauuuca acaaaaaaau      660

aauagacucc uagaaauaac aagagaauuu ucaguuaacg cagguguaac aaccccagua      720

uccaccuaua ugcuaacaaa uucagaauua cuuucccuaa ucaacgacau gcccauaaca      780

aaugaccaaa aaaaauuaau gucaaacaac guccaaauag uucgucaaca aucauauuca      840

auaaugugca uaauaaaaga agaagucuua gccuacguag uacaacuucc ccuuuaugga      900

guuaucgaca cacccugcug gaaacuccac acuucaccac uauguacuac aaacacaaaa      960

gaaggaucca acaucugccu cacaagaacc gaucgaggau gguacuguga uaacgccgga     1020

uccgucucau ucuucccaca agcagaaaca ugcaaaguac aaucaaacag aguauuuugc     1080

gacacaauga acucccucac auuaccuucu gaaguaaacc uauguaaugu agacauauuc     1140

aaccccaaau acgauugcaa aauaaugaca ucaaagacag auguaucauc aagugucauc     1200

acaucccuag gagcaauugu cucauguuau gguaaaacaa aaugcaccgc aucaaauaaa     1260

aacagaggca uaauaaaaac cuucucaaac gguugugacu acguauccaa uaaaggcguc     1320

gacacaguau caguagguaa cacauuauau uguguaaaca aacaagaagg acagucccua     1380

uauguaaaag gagaaccaau aaucaacuuc uacgacccac uuguuuuccc uucugaugaa     1440

uuugacgcaa guauaucaca aguaaaugaa aaaaucaauc aaucacuagc cuuuauaaga     1500

aaaucagaug aauuauuaca caacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaaucgucau aauagucauc cuacuaucac ucauagcagu uggacuccua     1620

cuauacugca aagcacgauc aacaccagua acauuaucca aagaccaacu aagugguauc     1680

aauaacaucg ccuuuucaaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1908
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1908
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau ccucaaagcc      120

aacgcaauca ccacaauccu cacugccguc accuucugcu ucgccuccgg ccaaaacaua      180

acagaagaau uuuaccaauc aaccuguuca gcggucucca aaggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgugaucacc auagaacucu ccaacaucaa ggaaaacaaa      300

ugcaacggca ccgacgcgaa ggucaaacuu auuaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuacaacu ccuaaugcag uccacgccag ccaccggcuc uggcucagcc      420

auaugcuccg guguggccgu augcaaaguc cuacaccucg aaggagaagu caacaaaaua      480

aaauccgccc uacuguccac aaacaaggcc guagucuccc ucucaaacgg cgucucagua      540

cucaccuuca aaguccuaga ccucaagaac uacaucgaca aacaacuccu acccauacua      600

aacaaacaau ccugcucaau ccccaacauc gaaaccguaa uagaauuuca acaaaaaaac      660

aacagacucc uggagaucac ccgggaauuu uccguaaacg ccggagucac aacacccguc      720

ucaaccuaca ugcuaacgaa cucagagcuc cucucacuua ucaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau guccaacaac gugcaaaucg uccgacaaca auccuacucc      840

aucaugugca ucauuaaaga agaaguccuc gcauacguag uccagcuccc ccucuacggc      900

gucauagaca cccccugcug gaaacuacac acaucacccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccgcacc gaccgaggcu gguacugcga uaacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc ugcaaggucc aauccaaccg aguuuucugc     1080

gacacuauga acucgcucac ccuccccucc gaagucaacc ucugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acguauccuc cuccgucauc     1200

accucccuag gcgccauagu aaguugcuac ggcaaaacca agugcacagc aagcaacaaa     1260

aaccgaggaa uaaucaaaac cuucuccaac ggcugcgacu acguauccaa caagggcguc     1320

gacaccguau ccguagggaa cacccuuuac ugcguaaaca aacaagaagg acaaucacuc     1380

uacguaaaag gcgaacccau aaucaacuuc uacgaccccc ucguauuucc cuccgacgaa     1440

uuugacgcau caaucucaca ggucaacgaa aaaauaaacc aaucgcuagc auucaucaga     1500

aaaucagacg aacuccuaca caacgucaac gcaggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgucau aaucgucaua cuacucucac ucauagcagu cggccuccuc     1620

cuauacugua aagcaagguc gaccccaguc acccuaucca aagaccaacu aagcggcauc     1680

aacaacaucg cguucucaaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  1909
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1909
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1910
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1910
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1911
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1911
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1912
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1912
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaccaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1913
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1913
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1914
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1914
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaccaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1915
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1915
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuaaaagca      120

aacgcuauaa caacaauacu aacagcaguc acauucugcu uugcaucagg ccaaaacauc      180

acagaagaau uuuaccaauc aacaugcucc gccguaucga aaggauaccu aggcgcauua      240

agaaccggau gguauacauc agucauaaca auugaacuau cuaacauaaa agaaaacaaa      300

uguaacggca cagaugccaa aguaaaacuc aucaaacaag aauuagauaa auacaaaaac      360

gcagucacug aacuacaacu cuuaaugcaa ucaacaccug caacaggauc aggaucagca      420

auaugcucag gaguagccgu auguaaagua cuacaccuag aaggagaagu caacaaaaua      480

aaaucagccc uccuaaguac aaacaaagcu gucguaucac uauccaaugg uguuucagua      540

cuaacuuuca aaguucuaga ccuaaaaaac uacauagaca aacaacuacu accaauacua      600

aauaaacaaa guuguucuau acccaacaua gaaaccguca uagaauuuca acaaaaaaau      660

aauagacucc uagaaauaac aagagaauuu ucaguuaacg cagguguaac aaccccagua      720

uccaccuaua ugcuaacaaa uucagaauua cuuucccuaa ucaacgacau gcccauaaca      780

aaugaccaaa aaaaauuaau gucaaacaac guccaaauag uucgucaaca aucauauuca      840

auaaugugca uaauaaaaga agaagucuua gccuacguag uacaacuucc ccuuuaugga      900

guuaucgaca cacccugcug gaaacuccac acuucaccac uauguacuac aaacacaaaa      960

gaaggaucca acaucugccu cacaagaacc gaucgaggau gguacuguga uaacgccgga     1020

uccgucucau ucuucccaca agcagaaaca ugcaaaguac aaucaaacag aguauuuugc     1080

gacacaauga acucccucac auuaccuucu gaaguaaacc uauguaaugu agacauauuc     1140

aaccccaaau acgauugcaa aauaaugaca ucaaagacag auguaucauc aagugucauc     1200

acaucccuag gagcaauugu cucauguuau gguaaaacaa aaugcaccgc aucaaauaaa     1260

aacagaggca uaauaaaaac cuucucaaac gguugugacu acguauccaa uaaaggcguc     1320

gacacaguau caguagguaa cacauuauau uguguaaaca aacaagaagg acagucccua     1380

uauguaaaag gagaaccaau aaucaacuuc uacgacccac uuguuuuccc uucugaugaa     1440

uuugacgcaa guauaucaca aguaaaugaa aaaaucaauc aaucacuagc cuuuauaaga     1500

aaaucagaug aauuauuaca caacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaaucgucau aauagucauc cuacuaucac ucauagcagu uggacuccua     1620

cuauacugca aagcacgauc aacaccagua acauuaucca aagaccaacu aagugguauc     1680

aauaacaucg ccuuuucaaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1916
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1916
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau ccucaaagcc      120

aacgcaauca ccacaauccu cacugccguc accuucugcu ucgccuccgg ccaaaacaua      180

acagaagaau uuuaccaauc aaccuguuca gcggucucca aaggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgugaucacc auagaacucu ccaacaucaa ggaaaacaaa      300

ugcaacggca ccgacgcgaa ggucaaacuu auuaaacaag aacucgacaa auacaaaaac      360

gcagucaccg aacuacaacu ccuaaugcag uccacgccag ccaccggcuc uggcucagcc      420

auaugcuccg guguggccgu augcaaaguc cuacaccucg aaggagaagu caacaaaaua      480

aaauccgccc uacuguccac aaacaaggcc guagucuccc ucucaaacgg cgucucagua      540

cucaccuuca aaguccuaga ccucaagaac uacaucgaca aacaacuccu acccauacua      600

aacaaacaau ccugcucaau ccccaacauc gaaaccguaa uagaauuuca acaaaaaaac      660

aacagacucc uggagaucac ccgggaauuu uccguaaacg ccggagucac aacacccguc      720

ucaaccuaca ugcuaacgaa cucagagcuc cucucacuua ucaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau guccaacaac gugcaaaucg uccgacaaca auccuacucc      840

aucaugugca ucauuaaaga agaaguccuc gcauacguag uccagcuccc ccucuacggc      900

gucauagaca cccccugcug gaaacuacac acaucacccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccgcacc gaccgaggcu gguacugcga uaacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc ugcaaggucc aauccaaccg aguuuucugc     1080

gacacuauga acucgcucac ccuccccucc gaagucaacc ucugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaagaccg acguauccuc cuccgucauc     1200

accucccuag gcgccauagu aaguugcuac ggcaaaacca agugcacagc aagcaacaaa     1260

aaccgaggaa uaaucaaaac cuucuccaac ggcugcgacu acguauccaa caagggcguc     1320

gacaccguau ccguagggaa cacccuuuac ugcguaaaca aacaagaagg acaaucacuc     1380

uacguaaaag gcgaacccau aaucaacuuc uacgaccccc ucguauuucc cuccgacgaa     1440

uuugacgcau caaucucaca ggucaacgaa aaaauaaacc aaucgcuagc auucaucaga     1500

aaaucagacg aacuccuaca caacgucaac gcaggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgucau aaucgucaua cuacucucac ucauagcagu cggccuccuc     1620

cuauacugua aagcaagguc gaccccaguc acccuaucca aagaccaacu aagcggcauc     1680

aacaacaucg cguucucaaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  1917
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1917
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1918
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1918
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1919
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1919
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1920
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1920
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag accaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1921
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1921
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1922
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1922
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag accaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1923
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1923
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu aaaagcaaac gcuauaacaa caauacuaac agcagucaca      180

uucugcuuug caucaggcca aaacaucaca gaagaauuuu accaaucaac augcuccgcc      240

guaucgaaag gauaccuagg cgcauuaaga accggauggu auacaucagu cauaacaauu      300

gaacuaucua acauaaaaga aaacaaaugu aacggcacag augccaaagu aaaacucauc      360

aaacaagaau uagauaaaua caaaaacgca gucacugaac uacaacucuu aaugcaauca      420

acaccugcaa caggaucagg aucagcaaua ugcucaggag uagccguaug uaaaguacua      480

caccuagaag gagaagucaa caaaauaaaa ucagcccucc uaaguacaaa caaagcuguc      540

guaucacuau ccaauggugu uucaguacua acuuucaaag uucuagaccu aaaaaacuac      600

auagacaaac aacuacuacc aauacuaaau aaacaaaguu guucuauacc caacauagaa      660

accgucauag aauuucaaca aaaaaauaau agacuccuag aaauaacaag agaauuuuca      720

guuaacgcag guguaacaac cccaguaucc accuauaugc uaacaaauuc agaauuacuu      780

ucccuaauca acgacaugcc cauaacaaau gaccaaaaaa aauuaauguc aaacaacguc      840

caaauaguuc gucaacaauc auauucaaua augugcauaa uaaaagaaga agucuuagcc      900

uacguaguac aacuuccccu uuauggaguu aucgacacac ccugcuggaa acuccacacu      960

ucaccacuau guacuacaaa cacaaaagaa ggauccaaca ucugccucac aagaaccgau     1020

cgaggauggu acugugauaa cgccggaucc gucucauucu ucccacaagc agaaacaugc     1080

aaaguacaau caaacagagu auuuugcgac acaaugaacu cccucacauu accuucugaa     1140

guaaaccuau guaauguaga cauauucaac cccaaauacg auugcaaaau aaugacauca     1200

aagacagaug uaucaucaag ugucaucaca ucccuaggag caauugucuc auguuauggu     1260

aaaacaaaau gcaccgcauc aaauaaaaac agaggcauaa uaaaaaccuu cucaaacggu     1320

ugugacuacg uauccaauaa aggcgucgac acaguaucag uagguaacac auuauauugu     1380

guaaacaaac aagaaggaca gucccuauau guaaaaggag aaccaauaau caacuucuac     1440

gacccacuug uuuucccuuc ugaugaauuu gacgcaagua uaucacaagu aaaugaaaaa     1500

aucaaucaau cacuagccuu uauaagaaaa ucagaugaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa ucgucauaau agucauccua     1620

cuaucacuca uagcaguugg acuccuacua uacugcaaag cacgaucaac accaguaaca     1680

uuauccaaag accaacuaag ugguaucaau aacaucgccu uuucaaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1924
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1924
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauccu caaagccaac gcaaucacca caauccucac ugccgucacc      180

uucugcuucg ccuccggcca aaacauaaca gaagaauuuu accaaucaac cuguucagcg      240

gucuccaaag gcuaccucgg cgcccuccgc accggcuggu acaccuccgu gaucaccaua      300

gaacucucca acaucaagga aaacaaaugc aacggcaccg acgcgaaggu caaacuuauu      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgaac uacaacuccu aaugcagucc      420

acgccagcca ccggcucugg cucagccaua ugcuccggug uggccguaug caaaguccua      480

caccucgaag gagaagucaa caaaauaaaa uccgcccuac uguccacaaa caaggccgua      540

gucucccucu caaacggcgu cucaguacuc accuucaaag uccuagaccu caagaacuac      600

aucgacaaac aacuccuacc cauacuaaac aaacaauccu gcucaauccc caacaucgaa      660

accguaauag aauuucaaca aaaaaacaac agacuccugg agaucacccg ggaauuuucc      720

guaaacgccg gagucacaac acccgucuca accuacaugc uaacgaacuc agagcuccuc      780

ucacuuauca acgacaugcc cauaacaaac gaccaaaaaa aacucauguc caacaacgug      840

caaaucgucc gacaacaauc cuacuccauc augugcauca uuaaagaaga aguccucgca      900

uacguagucc agcucccccu cuacggcguc auagacaccc ccugcuggaa acuacacaca      960

ucaccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgaggcuggu acugcgauaa cgccggcagc gucuccuucu ucccccaagc agaaaccugc     1080

aagguccaau ccaaccgagu uuucugcgac acuaugaacu cgcucacccu ccccuccgaa     1140

gucaaccucu gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucc     1200

aagaccgacg uauccuccuc cgucaucacc ucccuaggcg ccauaguaag uugcuacggc     1260

aaaaccaagu gcacagcaag caacaaaaac cgaggaauaa ucaaaaccuu cuccaacggc     1320

ugcgacuacg uauccaacaa gggcgucgac accguauccg uagggaacac ccuuuacugc     1380

guaaacaaac aagaaggaca aucacucuac guaaaaggcg aacccauaau caacuucuac     1440

gacccccucg uauuucccuc cgacgaauuu gacgcaucaa ucucacaggu caacgaaaaa     1500

auaaaccaau cgcuagcauu caucagaaaa ucagacgaac uccuacacaa cgucaacgca     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgucauaau cgucauacua     1620

cucucacuca uagcagucgg ccuccuccua uacuguaaag caaggucgac cccagucacc     1680

cuauccaaag accaacuaag cggcaucaac aacaucgcgu ucucaaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1925
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1925
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1926
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1926
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1927
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1927
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1928
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1928
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagacca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1929
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1929
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1930
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1930
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagacca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1931
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1931
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuaaaa      120

gcaaacgcua uaacaacaau acuaacagca gucacauucu gcuuugcauc aggccaaaac      180

aucacagaag aauuuuacca aucaacaugc uccgccguau cgaaaggaua ccuaggcgca      240

uuaagaaccg gaugguauac aucagucaua acaauugaac uaucuaacau aaaagaaaac      300

aaauguaacg gcacagaugc caaaguaaaa cucaucaaac aagaauuaga uaaauacaaa      360

aacgcaguca cugaacuaca acucuuaaug caaucaacac cugcaacagg aucaggauca      420

gcaauaugcu caggaguagc cguauguaaa guacuacacc uagaaggaga agucaacaaa      480

auaaaaucag cccuccuaag uacaaacaaa gcugucguau cacuauccaa ugguguuuca      540

guacuaacuu ucaaaguucu agaccuaaaa aacuacauag acaaacaacu acuaccaaua      600

cuaaauaaac aaaguuguuc uauacccaac auagaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac uccuagaaau aacaagagaa uuuucaguua acgcaggugu aacaacccca      720

guauccaccu auaugcuaac aaauucagaa uuacuuuccc uaaucaacga caugcccaua      780

acaaaugacc aaaaaaaauu aaugucaaac aacguccaaa uaguucguca acaaucauau      840

ucaauaaugu gcauaauaaa agaagaaguc uuagccuacg uaguacaacu uccccuuuau      900

ggaguuaucg acacacccug cuggaaacuc cacacuucac cacuauguac uacaaacaca      960

aaagaaggau ccaacaucug ccucacaaga accgaucgag gaugguacug ugauaacgcc     1020

ggauccgucu cauucuuccc acaagcagaa acaugcaaag uacaaucaaa cagaguauuu     1080

ugcgacacaa ugaacucccu cacauuaccu ucugaaguaa accuauguaa uguagacaua     1140

uucaacccca aauacgauug caaaauaaug acaucaaaga cagauguauc aucaaguguc     1200

aucacauccc uaggagcaau ugucucaugu uaugguaaaa caaaaugcac cgcaucaaau     1260

aaaaacagag gcauaauaaa aaccuucuca aacgguugug acuacguauc caauaaaggc     1320

gucgacacag uaucaguagg uaacacauua uauuguguaa acaaacaaga aggacagucc     1380

cuauauguaa aaggagaacc aauaaucaac uucuacgacc cacuuguuuu cccuucugau     1440

gaauuugacg caaguauauc acaaguaaau gaaaaaauca aucaaucacu agccuuuaua     1500

agaaaaucag augaauuauu acacaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaaucgu cauaauaguc auccuacuau cacucauagc aguuggacuc     1620

cuacuauacu gcaaagcacg aucaacacca guaacauuau ccaaagacca acuaaguggu     1680

aucaauaaca ucgccuuuuc aaacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1932
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1932
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauccucaaa      120

gccaacgcaa ucaccacaau ccucacugcc gucaccuucu gcuucgccuc cggccaaaac      180

auaacagaag aauuuuacca aucaaccugu ucagcggucu ccaaaggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgugauc accauagaac ucuccaacau caaggaaaac      300

aaaugcaacg gcaccgacgc gaaggucaaa cuuauuaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacuaca acuccuaaug caguccacgc cagccaccgg cucuggcuca      420

gccauaugcu ccgguguggc cguaugcaaa guccuacacc ucgaaggaga agucaacaaa      480

auaaaauccg cccuacuguc cacaaacaag gccguagucu cccucucaaa cggcgucuca      540

guacucaccu ucaaaguccu agaccucaag aacuacaucg acaaacaacu ccuacccaua      600

cuaaacaaac aauccugcuc aauccccaac aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagac uccuggagau cacccgggaa uuuuccguaa acgccggagu cacaacaccc      720

gucucaaccu acaugcuaac gaacucagag cuccucucac uuaucaacga caugcccaua      780

acaaacgacc aaaaaaaacu cauguccaac aacgugcaaa ucguccgaca acaauccuac      840

uccaucaugu gcaucauuaa agaagaaguc cucgcauacg uaguccagcu cccccucuac      900

ggcgucauag acacccccug cuggaaacua cacacaucac cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgc accgaccgag gcugguacug cgauaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accugcaagg uccaauccaa ccgaguuuuc     1080

ugcgacacua ugaacucgcu cacccucccc uccgaaguca accucugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accuccaaga ccgacguauc cuccuccguc     1200

aucaccuccc uaggcgccau aguaaguugc uacggcaaaa ccaagugcac agcaagcaac     1260

aaaaaccgag gaauaaucaa aaccuucucc aacggcugcg acuacguauc caacaagggc     1320

gucgacaccg uauccguagg gaacacccuu uacugcguaa acaaacaaga aggacaauca     1380

cucuacguaa aaggcgaacc cauaaucaac uucuacgacc cccucguauu ucccuccgac     1440

gaauuugacg caucaaucuc acaggucaac gaaaaaauaa accaaucgcu agcauucauc     1500

agaaaaucag acgaacuccu acacaacguc aacgcaggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu cauaaucguc auacuacucu cacucauagc agucggccuc     1620

cuccuauacu guaaagcaag gucgacccca gucacccuau ccaaagacca acuaagcggc     1680

aucaacaaca ucgcguucuc aaacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  1933
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1933
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1934
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1934
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1935
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1935
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1936
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1936
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagacca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1937
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1937
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1938
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1938
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagacca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1939
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1939
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuaaaa      120

gcaaacgcua uaacaacaau acuaacagca gucacauucu gcuuugcauc aggccaaaac      180

aucacagaag aauuuuacca aucaacaugc uccgccguau cgaaaggaua ccuaggcgca      240

uuaagaaccg gaugguauac aucagucaua acaauugaac uaucuaacau aaaagaaaac      300

aaauguaacg gcacagaugc caaaguaaaa cucaucaaac aagaauuaga uaaauacaaa      360

aacgcaguca cugaacuaca acucuuaaug caaucaacac cugcaacagg aucaggauca      420

gcaauaugcu caggaguagc cguauguaaa guacuacacc uagaaggaga agucaacaaa      480

auaaaaucag cccuccuaag uacaaacaaa gcugucguau cacuauccaa ugguguuuca      540

guacuaacuu ucaaaguucu agaccuaaaa aacuacauag acaaacaacu acuaccaaua      600

cuaaauaaac aaaguuguuc uauacccaac auagaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac uccuagaaau aacaagagaa uuuucaguua acgcaggugu aacaacccca      720

guauccaccu auaugcuaac aaauucagaa uuacuuuccc uaaucaacga caugcccaua      780

acaaaugacc aaaaaaaauu aaugucaaac aacguccaaa uaguucguca acaaucauau      840

ucaauaaugu gcauaauaaa agaagaaguc uuagccuacg uaguacaacu uccccuuuau      900

ggaguuaucg acacacccug cuggaaacuc cacacuucac cacuauguac uacaaacaca      960

aaagaaggau ccaacaucug ccucacaaga accgaucgag gaugguacug ugauaacgcc     1020

ggauccgucu cauucuuccc acaagcagaa acaugcaaag uacaaucaaa cagaguauuu     1080

ugcgacacaa ugaacucccu cacauuaccu ucugaaguaa accuauguaa uguagacaua     1140

uucaacccca aauacgauug caaaauaaug acaucaaaga cagauguauc aucaaguguc     1200

aucacauccc uaggagcaau ugucucaugu uaugguaaaa caaaaugcac cgcaucaaau     1260

aaaaacagag gcauaauaaa aaccuucuca aacgguugug acuacguauc caauaaaggc     1320

gucgacacag uaucaguagg uaacacauua uauuguguaa acaaacaaga aggacagucc     1380

cuauauguaa aaggagaacc aauaaucaac uucuacgacc cacuuguuuu cccuucugau     1440

gaauuugacg caaguauauc acaaguaaau gaaaaaauca aucaaucacu agccuuuaua     1500

agaaaaucag augaauuauu acacaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaaucgu cauaauaguc auccuacuau cacucauagc aguuggacuc     1620

cuacuauacu gcaaagcacg aucaacacca guaacauuau ccaaagacca acuaaguggu     1680

aucaauaaca ucgccuuuuc aaacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1940
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1940
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauccucaaa      120

gccaacgcaa ucaccacaau ccucacugcc gucaccuucu gcuucgccuc cggccaaaac      180

auaacagaag aauuuuacca aucaaccugu ucagcggucu ccaaaggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgugauc accauagaac ucuccaacau caaggaaaac      300

aaaugcaacg gcaccgacgc gaaggucaaa cuuauuaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacuaca acuccuaaug caguccacgc cagccaccgg cucuggcuca      420

gccauaugcu ccgguguggc cguaugcaaa guccuacacc ucgaaggaga agucaacaaa      480

auaaaauccg cccuacuguc cacaaacaag gccguagucu cccucucaaa cggcgucuca      540

guacucaccu ucaaaguccu agaccucaag aacuacaucg acaaacaacu ccuacccaua      600

cuaaacaaac aauccugcuc aauccccaac aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagac uccuggagau cacccgggaa uuuuccguaa acgccggagu cacaacaccc      720

gucucaaccu acaugcuaac gaacucagag cuccucucac uuaucaacga caugcccaua      780

acaaacgacc aaaaaaaacu cauguccaac aacgugcaaa ucguccgaca acaauccuac      840

uccaucaugu gcaucauuaa agaagaaguc cucgcauacg uaguccagcu cccccucuac      900

ggcgucauag acacccccug cuggaaacua cacacaucac cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgc accgaccgag gcugguacug cgauaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accugcaagg uccaauccaa ccgaguuuuc     1080

ugcgacacua ugaacucgcu cacccucccc uccgaaguca accucugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accuccaaga ccgacguauc cuccuccguc     1200

aucaccuccc uaggcgccau aguaaguugc uacggcaaaa ccaagugcac agcaagcaac     1260

aaaaaccgag gaauaaucaa aaccuucucc aacggcugcg acuacguauc caacaagggc     1320

gucgacaccg uauccguagg gaacacccuu uacugcguaa acaaacaaga aggacaauca     1380

cucuacguaa aaggcgaacc cauaaucaac uucuacgacc cccucguauu ucccuccgac     1440

gaauuugacg caucaaucuc acaggucaac gaaaaaauaa accaaucgcu agcauucauc     1500

agaaaaucag acgaacuccu acacaacguc aacgcaggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu cauaaucguc auacuacucu cacucauagc agucggccuc     1620

cuccuauacu guaaagcaag gucgacccca gucacccuau ccaaagacca acuaagcggc     1680

aucaacaaca ucgcguucuc aaacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  1941
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1941
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1942
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1942
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1943
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1943
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1944
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1944
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagacca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1945
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1945
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1946
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1946
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagacca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1947
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1947
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuaaaa      120

gcaaacgcua uaacaacaau acuaacagca gucacauucu gcuuugcauc aggccaaaac      180

aucacagaag aauuuuacca aucaacaugc uccgccguau cgaaaggaua ccuaggcgca      240

uuaagaaccg gaugguauac aucagucaua acaauugaac uaucuaacau aaaagaaaac      300

aaauguaacg gcacagaugc caaaguaaaa cucaucaaac aagaauuaga uaaauacaaa      360

aacgcaguca cugaacuaca acucuuaaug caaucaacac cugcaacagg aucaggauca      420

gcaauaugcu caggaguagc cguauguaaa guacuacacc uagaaggaga agucaacaaa      480

auaaaaucag cccuccuaag uacaaacaaa gcugucguau cacuauccaa ugguguuuca      540

guacuaacuu ucaaaguucu agaccuaaaa aacuacauag acaaacaacu acuaccaaua      600

cuaaauaaac aaaguuguuc uauacccaac auagaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac uccuagaaau aacaagagaa uuuucaguua acgcaggugu aacaacccca      720

guauccaccu auaugcuaac aaauucagaa uuacuuuccc uaaucaacga caugcccaua      780

acaaaugacc aaaaaaaauu aaugucaaac aacguccaaa uaguucguca acaaucauau      840

ucaauaaugu gcauaauaaa agaagaaguc uuagccuacg uaguacaacu uccccuuuau      900

ggaguuaucg acacacccug cuggaaacuc cacacuucac cacuauguac uacaaacaca      960

aaagaaggau ccaacaucug ccucacaaga accgaucgag gaugguacug ugauaacgcc     1020

ggauccgucu cauucuuccc acaagcagaa acaugcaaag uacaaucaaa cagaguauuu     1080

ugcgacacaa ugaacucccu cacauuaccu ucugaaguaa accuauguaa uguagacaua     1140

uucaacccca aauacgauug caaaauaaug acaucaaaga cagauguauc aucaaguguc     1200

aucacauccc uaggagcaau ugucucaugu uaugguaaaa caaaaugcac cgcaucaaau     1260

aaaaacagag gcauaauaaa aaccuucuca aacgguugug acuacguauc caauaaaggc     1320

gucgacacag uaucaguagg uaacacauua uauuguguaa acaaacaaga aggacagucc     1380

cuauauguaa aaggagaacc aauaaucaac uucuacgacc cacuuguuuu cccuucugau     1440

gaauuugacg caaguauauc acaaguaaau gaaaaaauca aucaaucacu agccuuuaua     1500

agaaaaucag augaauuauu acacaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaaucgu cauaauaguc auccuacuau cacucauagc aguuggacuc     1620

cuacuauacu gcaaagcacg aucaacacca guaacauuau ccaaagacca acuaaguggu     1680

aucaauaaca ucgccuuuuc aaacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1948
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1948
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauccucaaa      120

gccaacgcaa ucaccacaau ccucacugcc gucaccuucu gcuucgccuc cggccaaaac      180

auaacagaag aauuuuacca aucaaccugu ucagcggucu ccaaaggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgugauc accauagaac ucuccaacau caaggaaaac      300

aaaugcaacg gcaccgacgc gaaggucaaa cuuauuaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacuaca acuccuaaug caguccacgc cagccaccgg cucuggcuca      420

gccauaugcu ccgguguggc cguaugcaaa guccuacacc ucgaaggaga agucaacaaa      480

auaaaauccg cccuacuguc cacaaacaag gccguagucu cccucucaaa cggcgucuca      540

guacucaccu ucaaaguccu agaccucaag aacuacaucg acaaacaacu ccuacccaua      600

cuaaacaaac aauccugcuc aauccccaac aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagac uccuggagau cacccgggaa uuuuccguaa acgccggagu cacaacaccc      720

gucucaaccu acaugcuaac gaacucagag cuccucucac uuaucaacga caugcccaua      780

acaaacgacc aaaaaaaacu cauguccaac aacgugcaaa ucguccgaca acaauccuac      840

uccaucaugu gcaucauuaa agaagaaguc cucgcauacg uaguccagcu cccccucuac      900

ggcgucauag acacccccug cuggaaacua cacacaucac cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgc accgaccgag gcugguacug cgauaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accugcaagg uccaauccaa ccgaguuuuc     1080

ugcgacacua ugaacucgcu cacccucccc uccgaaguca accucugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accuccaaga ccgacguauc cuccuccguc     1200

aucaccuccc uaggcgccau aguaaguugc uacggcaaaa ccaagugcac agcaagcaac     1260

aaaaaccgag gaauaaucaa aaccuucucc aacggcugcg acuacguauc caacaagggc     1320

gucgacaccg uauccguagg gaacacccuu uacugcguaa acaaacaaga aggacaauca     1380

cucuacguaa aaggcgaacc cauaaucaac uucuacgacc cccucguauu ucccuccgac     1440

gaauuugacg caucaaucuc acaggucaac gaaaaaauaa accaaucgcu agcauucauc     1500

agaaaaucag acgaacuccu acacaacguc aacgcaggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu cauaaucguc auacuacucu cacucauagc agucggccuc     1620

cuccuauacu guaaagcaag gucgacccca gucacccuau ccaaagacca acuaagcggc     1680

aucaacaaca ucgcguucuc aaacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  1949
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1949
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1950
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1950
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1951
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1951
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1952
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1952
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagacca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1953
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1953
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1954
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1954
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagacca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1955
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1955
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuaaaa      120

gcaaacgcua uaacaacaau acuaacagca gucacauucu gcuuugcauc aggccaaaac      180

aucacagaag aauuuuacca aucaacaugc uccgccguau cgaaaggaua ccuaggcgca      240

uuaagaaccg gaugguauac aucagucaua acaauugaac uaucuaacau aaaagaaaac      300

aaauguaacg gcacagaugc caaaguaaaa cucaucaaac aagaauuaga uaaauacaaa      360

aacgcaguca cugaacuaca acucuuaaug caaucaacac cugcaacagg aucaggauca      420

gcaauaugcu caggaguagc cguauguaaa guacuacacc uagaaggaga agucaacaaa      480

auaaaaucag cccuccuaag uacaaacaaa gcugucguau cacuauccaa ugguguuuca      540

guacuaacuu ucaaaguucu agaccuaaaa aacuacauag acaaacaacu acuaccaaua      600

cuaaauaaac aaaguuguuc uauacccaac auagaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac uccuagaaau aacaagagaa uuuucaguua acgcaggugu aacaacccca      720

guauccaccu auaugcuaac aaauucagaa uuacuuuccc uaaucaacga caugcccaua      780

acaaaugacc aaaaaaaauu aaugucaaac aacguccaaa uaguucguca acaaucauau      840

ucaauaaugu gcauaauaaa agaagaaguc uuagccuacg uaguacaacu uccccuuuau      900

ggaguuaucg acacacccug cuggaaacuc cacacuucac cacuauguac uacaaacaca      960

aaagaaggau ccaacaucug ccucacaaga accgaucgag gaugguacug ugauaacgcc     1020

ggauccgucu cauucuuccc acaagcagaa acaugcaaag uacaaucaaa cagaguauuu     1080

ugcgacacaa ugaacucccu cacauuaccu ucugaaguaa accuauguaa uguagacaua     1140

uucaacccca aauacgauug caaaauaaug acaucaaaga cagauguauc aucaaguguc     1200

aucacauccc uaggagcaau ugucucaugu uaugguaaaa caaaaugcac cgcaucaaau     1260

aaaaacagag gcauaauaaa aaccuucuca aacgguugug acuacguauc caauaaaggc     1320

gucgacacag uaucaguagg uaacacauua uauuguguaa acaaacaaga aggacagucc     1380

cuauauguaa aaggagaacc aauaaucaac uucuacgacc cacuuguuuu cccuucugau     1440

gaauuugacg caaguauauc acaaguaaau gaaaaaauca aucaaucacu agccuuuaua     1500

agaaaaucag augaauuauu acacaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaaucgu cauaauaguc auccuacuau cacucauagc aguuggacuc     1620

cuacuauacu gcaaagcacg aucaacacca guaacauuau ccaaagacca acuaaguggu     1680

aucaauaaca ucgccuuuuc aaacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1956
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1956
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauccucaaa      120

gccaacgcaa ucaccacaau ccucacugcc gucaccuucu gcuucgccuc cggccaaaac      180

auaacagaag aauuuuacca aucaaccugu ucagcggucu ccaaaggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgugauc accauagaac ucuccaacau caaggaaaac      300

aaaugcaacg gcaccgacgc gaaggucaaa cuuauuaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaacuaca acuccuaaug caguccacgc cagccaccgg cucuggcuca      420

gccauaugcu ccgguguggc cguaugcaaa guccuacacc ucgaaggaga agucaacaaa      480

auaaaauccg cccuacuguc cacaaacaag gccguagucu cccucucaaa cggcgucuca      540

guacucaccu ucaaaguccu agaccucaag aacuacaucg acaaacaacu ccuacccaua      600

cuaaacaaac aauccugcuc aauccccaac aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagac uccuggagau cacccgggaa uuuuccguaa acgccggagu cacaacaccc      720

gucucaaccu acaugcuaac gaacucagag cuccucucac uuaucaacga caugcccaua      780

acaaacgacc aaaaaaaacu cauguccaac aacgugcaaa ucguccgaca acaauccuac      840

uccaucaugu gcaucauuaa agaagaaguc cucgcauacg uaguccagcu cccccucuac      900

ggcgucauag acacccccug cuggaaacua cacacaucac cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgc accgaccgag gcugguacug cgauaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accugcaagg uccaauccaa ccgaguuuuc     1080

ugcgacacua ugaacucgcu cacccucccc uccgaaguca accucugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accuccaaga ccgacguauc cuccuccguc     1200

aucaccuccc uaggcgccau aguaaguugc uacggcaaaa ccaagugcac agcaagcaac     1260

aaaaaccgag gaauaaucaa aaccuucucc aacggcugcg acuacguauc caacaagggc     1320

gucgacaccg uauccguagg gaacacccuu uacugcguaa acaaacaaga aggacaauca     1380

cucuacguaa aaggcgaacc cauaaucaac uucuacgacc cccucguauu ucccuccgac     1440

gaauuugacg caucaaucuc acaggucaac gaaaaaauaa accaaucgcu agcauucauc     1500

agaaaaucag acgaacuccu acacaacguc aacgcaggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu cauaaucguc auacuacucu cacucauagc agucggccuc     1620

cuccuauacu guaaagcaag gucgacccca gucacccuau ccaaagacca acuaagcggc     1680

aucaacaaca ucgcguucuc aaacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  1957
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1957
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1958
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1958
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1959
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1959
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1960
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1960
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaccaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1961
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1961
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1962
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1962
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaccaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1963
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1963
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uaaaagcaaa cgcuauaaca acaauacuaa cagcagucac auucugcuuu      240

gcaucaggcc aaaacaucac agaagaauuu uaccaaucaa caugcuccgc cguaucgaaa      300

ggauaccuag gcgcauuaag aaccggaugg uauacaucag ucauaacaau ugaacuaucu      360

aacauaaaag aaaacaaaug uaacggcaca gaugccaaag uaaaacucau caaacaagaa      420

uuagauaaau acaaaaacgc agucacugaa cuacaacucu uaaugcaauc aacaccugca      480

acaggaucag gaucagcaau augcucagga guagccguau guaaaguacu acaccuagaa      540

ggagaaguca acaaaauaaa aucagcccuc cuaaguacaa acaaagcugu cguaucacua      600

uccaauggug uuucaguacu aacuuucaaa guucuagacc uaaaaaacua cauagacaaa      660

caacuacuac caauacuaaa uaaacaaagu uguucuauac ccaacauaga aaccgucaua      720

gaauuucaac aaaaaaauaa uagacuccua gaaauaacaa gagaauuuuc aguuaacgca      780

gguguaacaa ccccaguauc caccuauaug cuaacaaauu cagaauuacu uucccuaauc      840

aacgacaugc ccauaacaaa ugaccaaaaa aaauuaaugu caaacaacgu ccaaauaguu      900

cgucaacaau cauauucaau aaugugcaua auaaaagaag aagucuuagc cuacguagua      960

caacuucccc uuuauggagu uaucgacaca cccugcugga aacuccacac uucaccacua     1020

uguacuacaa acacaaaaga aggauccaac aucugccuca caagaaccga ucgaggaugg     1080

uacugugaua acgccggauc cgucucauuc uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuugcga cacaaugaac ucccucacau uaccuucuga aguaaaccua     1200

uguaauguag acauauucaa ccccaaauac gauugcaaaa uaaugacauc aaagacagau     1260

guaucaucaa gugucaucac aucccuagga gcaauugucu cauguuaugg uaaaacaaaa     1320

ugcaccgcau caaauaaaaa cagaggcaua auaaaaaccu ucucaaacgg uugugacuac     1380

guauccaaua aaggcgucga cacaguauca guagguaaca cauuauauug uguaaacaaa     1440

caagaaggac agucccuaua uguaaaagga gaaccaauaa ucaacuucua cgacccacuu     1500

guuuucccuu cugaugaauu ugacgcaagu auaucacaag uaaaugaaaa aaucaaucaa     1560

ucacuagccu uuauaagaaa aucagaugaa uuauuacaca acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua aucgucauaa uagucauccu acuaucacuc     1680

auagcaguug gacuccuacu auacugcaaa gcacgaucaa caccaguaac auuauccaaa     1740

gaccaacuaa gugguaucaa uaacaucgcc uuuucaaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1964
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1964
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaaucc ucaaagccaa cgcaaucacc acaauccuca cugccgucac cuucugcuuc      240

gccuccggcc aaaacauaac agaagaauuu uaccaaucaa ccuguucagc ggucuccaaa      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ugaucaccau agaacucucc      360

aacaucaagg aaaacaaaug caacggcacc gacgcgaagg ucaaacuuau uaaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuacaacucc uaaugcaguc cacgccagcc      480

accggcucug gcucagccau augcuccggu guggccguau gcaaaguccu acaccucgaa      540

ggagaaguca acaaaauaaa auccgcccua cuguccacaa acaaggccgu agucucccuc      600

ucaaacggcg ucucaguacu caccuucaaa guccuagacc ucaagaacua caucgacaaa      660

caacuccuac ccauacuaaa caaacaaucc ugcucaaucc ccaacaucga aaccguaaua      720

gaauuucaac aaaaaaacaa cagacuccug gagaucaccc gggaauuuuc cguaaacgcc      780

ggagucacaa cacccgucuc aaccuacaug cuaacgaacu cagagcuccu cucacuuauc      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu ccaacaacgu gcaaaucguc      900

cgacaacaau ccuacuccau caugugcauc auuaaagaag aaguccucgc auacguaguc      960

cagcuccccc ucuacggcgu cauagacacc cccugcugga aacuacacac aucaccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccgcaccga ccgaggcugg     1080

uacugcgaua acgccggcag cgucuccuuc uucccccaag cagaaaccug caagguccaa     1140

uccaaccgag uuuucugcga cacuaugaac ucgcucaccc uccccuccga agucaaccuc     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

guauccuccu ccgucaucac cucccuaggc gccauaguaa guugcuacgg caaaaccaag     1320

ugcacagcaa gcaacaaaaa ccgaggaaua aucaaaaccu ucuccaacgg cugcgacuac     1380

guauccaaca agggcgucga caccguaucc guagggaaca cccuuuacug cguaaacaaa     1440

caagaaggac aaucacucua cguaaaaggc gaacccauaa ucaacuucua cgacccccuc     1500

guauuucccu ccgacgaauu ugacgcauca aucucacagg ucaacgaaaa aauaaaccaa     1560

ucgcuagcau ucaucagaaa aucagacgaa cuccuacaca acgucaacgc aggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgucauaa ucgucauacu acucucacuc     1680

auagcagucg gccuccuccu auacuguaaa gcaaggucga ccccagucac ccuauccaaa     1740

gaccaacuaa gcggcaucaa caacaucgcg uucucaaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  1965
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1965
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1966
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1966
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1967
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1967
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1968
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1968
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaccaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1969
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1969
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1970
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1970
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaccaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1971
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1971
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uaaaagcaaa cgcuauaaca acaauacuaa cagcagucac auucugcuuu      240

gcaucaggcc aaaacaucac agaagaauuu uaccaaucaa caugcuccgc cguaucgaaa      300

ggauaccuag gcgcauuaag aaccggaugg uauacaucag ucauaacaau ugaacuaucu      360

aacauaaaag aaaacaaaug uaacggcaca gaugccaaag uaaaacucau caaacaagaa      420

uuagauaaau acaaaaacgc agucacugaa cuacaacucu uaaugcaauc aacaccugca      480

acaggaucag gaucagcaau augcucagga guagccguau guaaaguacu acaccuagaa      540

ggagaaguca acaaaauaaa aucagcccuc cuaaguacaa acaaagcugu cguaucacua      600

uccaauggug uuucaguacu aacuuucaaa guucuagacc uaaaaaacua cauagacaaa      660

caacuacuac caauacuaaa uaaacaaagu uguucuauac ccaacauaga aaccgucaua      720

gaauuucaac aaaaaaauaa uagacuccua gaaauaacaa gagaauuuuc aguuaacgca      780

gguguaacaa ccccaguauc caccuauaug cuaacaaauu cagaauuacu uucccuaauc      840

aacgacaugc ccauaacaaa ugaccaaaaa aaauuaaugu caaacaacgu ccaaauaguu      900

cgucaacaau cauauucaau aaugugcaua auaaaagaag aagucuuagc cuacguagua      960

caacuucccc uuuauggagu uaucgacaca cccugcugga aacuccacac uucaccacua     1020

uguacuacaa acacaaaaga aggauccaac aucugccuca caagaaccga ucgaggaugg     1080

uacugugaua acgccggauc cgucucauuc uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuugcga cacaaugaac ucccucacau uaccuucuga aguaaaccua     1200

uguaauguag acauauucaa ccccaaauac gauugcaaaa uaaugacauc aaagacagau     1260

guaucaucaa gugucaucac aucccuagga gcaauugucu cauguuaugg uaaaacaaaa     1320

ugcaccgcau caaauaaaaa cagaggcaua auaaaaaccu ucucaaacgg uugugacuac     1380

guauccaaua aaggcgucga cacaguauca guagguaaca cauuauauug uguaaacaaa     1440

caagaaggac agucccuaua uguaaaagga gaaccaauaa ucaacuucua cgacccacuu     1500

guuuucccuu cugaugaauu ugacgcaagu auaucacaag uaaaugaaaa aaucaaucaa     1560

ucacuagccu uuauaagaaa aucagaugaa uuauuacaca acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua aucgucauaa uagucauccu acuaucacuc     1680

auagcaguug gacuccuacu auacugcaaa gcacgaucaa caccaguaac auuauccaaa     1740

gaccaacuaa gugguaucaa uaacaucgcc uuuucaaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1972
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1972
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaaucc ucaaagccaa cgcaaucacc acaauccuca cugccgucac cuucugcuuc      240

gccuccggcc aaaacauaac agaagaauuu uaccaaucaa ccuguucagc ggucuccaaa      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ugaucaccau agaacucucc      360

aacaucaagg aaaacaaaug caacggcacc gacgcgaagg ucaaacuuau uaaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuacaacucc uaaugcaguc cacgccagcc      480

accggcucug gcucagccau augcuccggu guggccguau gcaaaguccu acaccucgaa      540

ggagaaguca acaaaauaaa auccgcccua cuguccacaa acaaggccgu agucucccuc      600

ucaaacggcg ucucaguacu caccuucaaa guccuagacc ucaagaacua caucgacaaa      660

caacuccuac ccauacuaaa caaacaaucc ugcucaaucc ccaacaucga aaccguaaua      720

gaauuucaac aaaaaaacaa cagacuccug gagaucaccc gggaauuuuc cguaaacgcc      780

ggagucacaa cacccgucuc aaccuacaug cuaacgaacu cagagcuccu cucacuuauc      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu ccaacaacgu gcaaaucguc      900

cgacaacaau ccuacuccau caugugcauc auuaaagaag aaguccucgc auacguaguc      960

cagcuccccc ucuacggcgu cauagacacc cccugcugga aacuacacac aucaccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccgcaccga ccgaggcugg     1080

uacugcgaua acgccggcag cgucuccuuc uucccccaag cagaaaccug caagguccaa     1140

uccaaccgag uuuucugcga cacuaugaac ucgcucaccc uccccuccga agucaaccuc     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

guauccuccu ccgucaucac cucccuaggc gccauaguaa guugcuacgg caaaaccaag     1320

ugcacagcaa gcaacaaaaa ccgaggaaua aucaaaaccu ucuccaacgg cugcgacuac     1380

guauccaaca agggcgucga caccguaucc guagggaaca cccuuuacug cguaaacaaa     1440

caagaaggac aaucacucua cguaaaaggc gaacccauaa ucaacuucua cgacccccuc     1500

guauuucccu ccgacgaauu ugacgcauca aucucacagg ucaacgaaaa aauaaaccaa     1560

ucgcuagcau ucaucagaaa aucagacgaa cuccuacaca acgucaacgc aggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgucauaa ucgucauacu acucucacuc     1680

auagcagucg gccuccuccu auacuguaaa gcaaggucga ccccagucac ccuauccaaa     1740

gaccaacuaa gcggcaucaa caacaucgcg uucucaaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  1973
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1973
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1974
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1974
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1975
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1975
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1976
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1976
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaccaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1977
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1977
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1978
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1978
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaccaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1979
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1979
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uaaaagcaaa cgcuauaaca acaauacuaa cagcagucac auucugcuuu      240

gcaucaggcc aaaacaucac agaagaauuu uaccaaucaa caugcuccgc cguaucgaaa      300

ggauaccuag gcgcauuaag aaccggaugg uauacaucag ucauaacaau ugaacuaucu      360

aacauaaaag aaaacaaaug uaacggcaca gaugccaaag uaaaacucau caaacaagaa      420

uuagauaaau acaaaaacgc agucacugaa cuacaacucu uaaugcaauc aacaccugca      480

acaggaucag gaucagcaau augcucagga guagccguau guaaaguacu acaccuagaa      540

ggagaaguca acaaaauaaa aucagcccuc cuaaguacaa acaaagcugu cguaucacua      600

uccaauggug uuucaguacu aacuuucaaa guucuagacc uaaaaaacua cauagacaaa      660

caacuacuac caauacuaaa uaaacaaagu uguucuauac ccaacauaga aaccgucaua      720

gaauuucaac aaaaaaauaa uagacuccua gaaauaacaa gagaauuuuc aguuaacgca      780

gguguaacaa ccccaguauc caccuauaug cuaacaaauu cagaauuacu uucccuaauc      840

aacgacaugc ccauaacaaa ugaccaaaaa aaauuaaugu caaacaacgu ccaaauaguu      900

cgucaacaau cauauucaau aaugugcaua auaaaagaag aagucuuagc cuacguagua      960

caacuucccc uuuauggagu uaucgacaca cccugcugga aacuccacac uucaccacua     1020

uguacuacaa acacaaaaga aggauccaac aucugccuca caagaaccga ucgaggaugg     1080

uacugugaua acgccggauc cgucucauuc uucccacaag cagaaacaug caaaguacaa     1140

ucaaacagag uauuuugcga cacaaugaac ucccucacau uaccuucuga aguaaaccua     1200

uguaauguag acauauucaa ccccaaauac gauugcaaaa uaaugacauc aaagacagau     1260

guaucaucaa gugucaucac aucccuagga gcaauugucu cauguuaugg uaaaacaaaa     1320

ugcaccgcau caaauaaaaa cagaggcaua auaaaaaccu ucucaaacgg uugugacuac     1380

guauccaaua aaggcgucga cacaguauca guagguaaca cauuauauug uguaaacaaa     1440

caagaaggac agucccuaua uguaaaagga gaaccaauaa ucaacuucua cgacccacuu     1500

guuuucccuu cugaugaauu ugacgcaagu auaucacaag uaaaugaaaa aaucaaucaa     1560

ucacuagccu uuauaagaaa aucagaugaa uuauuacaca acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua aucgucauaa uagucauccu acuaucacuc     1680

auagcaguug gacuccuacu auacugcaaa gcacgaucaa caccaguaac auuauccaaa     1740

gaccaacuaa gugguaucaa uaacaucgcc uuuucaaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1980
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1980
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaaucc ucaaagccaa cgcaaucacc acaauccuca cugccgucac cuucugcuuc      240

gccuccggcc aaaacauaac agaagaauuu uaccaaucaa ccuguucagc ggucuccaaa      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ugaucaccau agaacucucc      360

aacaucaagg aaaacaaaug caacggcacc gacgcgaagg ucaaacuuau uaaacaagaa      420

cucgacaaau acaaaaacgc agucaccgaa cuacaacucc uaaugcaguc cacgccagcc      480

accggcucug gcucagccau augcuccggu guggccguau gcaaaguccu acaccucgaa      540

ggagaaguca acaaaauaaa auccgcccua cuguccacaa acaaggccgu agucucccuc      600

ucaaacggcg ucucaguacu caccuucaaa guccuagacc ucaagaacua caucgacaaa      660

caacuccuac ccauacuaaa caaacaaucc ugcucaaucc ccaacaucga aaccguaaua      720

gaauuucaac aaaaaaacaa cagacuccug gagaucaccc gggaauuuuc cguaaacgcc      780

ggagucacaa cacccgucuc aaccuacaug cuaacgaacu cagagcuccu cucacuuauc      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu ccaacaacgu gcaaaucguc      900

cgacaacaau ccuacuccau caugugcauc auuaaagaag aaguccucgc auacguaguc      960

cagcuccccc ucuacggcgu cauagacacc cccugcugga aacuacacac aucaccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccgcaccga ccgaggcugg     1080

uacugcgaua acgccggcag cgucuccuuc uucccccaag cagaaaccug caagguccaa     1140

uccaaccgag uuuucugcga cacuaugaac ucgcucaccc uccccuccga agucaaccuc     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc caagaccgac     1260

guauccuccu ccgucaucac cucccuaggc gccauaguaa guugcuacgg caaaaccaag     1320

ugcacagcaa gcaacaaaaa ccgaggaaua aucaaaaccu ucuccaacgg cugcgacuac     1380

guauccaaca agggcgucga caccguaucc guagggaaca cccuuuacug cguaaacaaa     1440

caagaaggac aaucacucua cguaaaaggc gaacccauaa ucaacuucua cgacccccuc     1500

guauuucccu ccgacgaauu ugacgcauca aucucacagg ucaacgaaaa aauaaaccaa     1560

ucgcuagcau ucaucagaaa aucagacgaa cuccuacaca acgucaacgc aggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgucauaa ucgucauacu acucucacuc     1680

auagcagucg gccuccuccu auacuguaaa gcaaggucga ccccagucac ccuauccaaa     1740

gaccaacuaa gcggcaucaa caacaucgcg uucucaaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1981
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1981
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1982
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1982
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1620

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1983
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1983
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1984
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1984
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      720

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg      960

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1020

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1080

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1140

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1380

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1440

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1620

aaagaccaac ucucugggau aaacaauauc gcauucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1985
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1985
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1986
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1986
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      720

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc      960

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1080

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1140

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1380

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1440

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1620

aaagaccaac ucuccggaau uaacaauauc gcuuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1987
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1987
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuauuaa uacuaaaagc aaacgcuaua acaacaauac uaacagcagu cacauucugc      120

uuugcaucag gccaaaacau cacagaagaa uuuuaccaau caacaugcuc cgccguaucg      180

aaaggauacc uaggcgcauu aagaaccgga ugguauacau cagucauaac aauugaacua      240

ucuaacauaa aagaaaacaa auguaacggc acagaugcca aaguaaaacu caucaaacaa      300

gaauuagaua aauacaaaaa cgcagucacu gaacuacaac ucuuaaugca aucaacaccu      360

gcaacaggau caggaucagc aauaugcuca ggaguagccg uauguaaagu acuacaccua      420

gaaggagaag ucaacaaaau aaaaucagcc cuccuaagua caaacaaagc ugucguauca      480

cuauccaaug guguuucagu acuaacuuuc aaaguucuag accuaaaaaa cuacauagac      540

aaacaacuac uaccaauacu aaauaaacaa aguuguucua uacccaacau agaaaccguc      600

auagaauuuc aacaaaaaaa uaauagacuc cuagaaauaa caagagaauu uucaguuaac      660

gcagguguaa caaccccagu auccaccuau augcuaacaa auucagaauu acuuucccua      720

aucaacgaca ugcccauaac aaaugaccaa aaaaaauuaa ugucaaacaa cguccaaaua      780

guucgucaac aaucauauuc aauaaugugc auaauaaaag aagaagucuu agccuacgua      840

guacaacuuc cccuuuaugg aguuaucgac acacccugcu ggaaacucca cacuucacca      900

cuauguacua caaacacaaa agaaggaucc aacaucugcc ucacaagaac cgaucgagga      960

ugguacugug auaacgccgg auccgucuca uucuucccac aagcagaaac augcaaagua     1020

caaucaaaca gaguauuuug cgacacaaug aacucccuca cauuaccuuc ugaaguaaac     1080

cuauguaaug uagacauauu caaccccaaa uacgauugca aaauaaugac aucaaagaca     1140

gauguaucau caagugucau cacaucccua ggagcaauug ucucauguua ugguaaaaca     1200

aaaugcaccg caucaaauaa aaacagaggc auaauaaaaa ccuucucaaa cgguugugac     1260

uacguaucca auaaaggcgu cgacacagua ucaguaggua acacauuaua uuguguaaac     1320

aaacaagaag gacagucccu auauguaaaa ggagaaccaa uaaucaacuu cuacgaccca     1380

cuuguuuucc cuucugauga auuugacgca aguauaucac aaguaaauga aaaaaucaau     1440

caaucacuag ccuuuauaag aaaaucagau gaauuauuac acaacguaaa cgccggaaaa     1500

ucaacaacca acauaaugau aaccacaaua auaaucguca uaauagucau ccuacuauca     1560

cucauagcag uuggacuccu acuauacugc aaagcacgau caacaccagu aacauuaucc     1620

aaagaccaac uaagugguau caauaacauc gccuuuucaa acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1988
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1988
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuaa uccucaaagc caacgcaauc accacaaucc ucacugccgu caccuucugc      120

uucgccuccg gccaaaacau aacagaagaa uuuuaccaau caaccuguuc agcggucucc      180

aaaggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgugaucac cauagaacuc      240

uccaacauca aggaaaacaa augcaacggc accgacgcga aggucaaacu uauuaaacaa      300

gaacucgaca aauacaaaaa cgcagucacc gaacuacaac uccuaaugca guccacgcca      360

gccaccggcu cuggcucagc cauaugcucc gguguggccg uaugcaaagu ccuacaccuc      420

gaaggagaag ucaacaaaau aaaauccgcc cuacugucca caaacaaggc cguagucucc      480

cucucaaacg gcgucucagu acucaccuuc aaaguccuag accucaagaa cuacaucgac      540

aaacaacucc uacccauacu aaacaaacaa uccugcucaa uccccaacau cgaaaccgua      600

auagaauuuc aacaaaaaaa caacagacuc cuggagauca cccgggaauu uuccguaaac      660

gccggaguca caacacccgu cucaaccuac augcuaacga acucagagcu ccucucacuu      720

aucaacgaca ugcccauaac aaacgaccaa aaaaaacuca uguccaacaa cgugcaaauc      780

guccgacaac aauccuacuc caucaugugc aucauuaaag aagaaguccu cgcauacgua      840

guccagcucc cccucuacgg cgucauagac acccccugcu ggaaacuaca cacaucaccc      900

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccgcac cgaccgaggc      960

ugguacugcg auaacgccgg cagcgucucc uucuuccccc aagcagaaac cugcaagguc     1020

caauccaacc gaguuuucug cgacacuaug aacucgcuca cccuccccuc cgaagucaac     1080

cucugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cuccaagacc     1140

gacguauccu ccuccgucau caccucccua ggcgccauag uaaguugcua cggcaaaacc     1200

aagugcacag caagcaacaa aaaccgagga auaaucaaaa ccuucuccaa cggcugcgac     1260

uacguaucca acaagggcgu cgacaccgua uccguaggga acacccuuua cugcguaaac     1320

aaacaagaag gacaaucacu cuacguaaaa ggcgaaccca uaaucaacuu cuacgacccc     1380

cucguauuuc ccuccgacga auuugacgca ucaaucucac aggucaacga aaaaauaaac     1440

caaucgcuag cauucaucag aaaaucagac gaacuccuac acaacgucaa cgcaggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguca uaaucgucau acuacucuca     1560

cucauagcag ucggccuccu ccuauacugu aaagcaaggu cgaccccagu cacccuaucc     1620

aaagaccaac uaagcggcau caacaacauc gcguucucaa acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  1989
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1989
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc cuguccaagg     1620

accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1990
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1990
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug gucagccucu      480

ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug agccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac cggggcuggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag gucaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc gucaacaagc     1320

aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac gacccccugg     1380

uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc cugagcaagg     1620

accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1991
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1991
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc cucuccaagg     1620

accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1992
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  1992
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug caccucgagg      420

gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug gucucccucu      480

cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac auugauaaac      540

aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu gucaacgccg      660

gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug ucccucauca      720

acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc cagaucguuc      780

gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg uauguagugc      840

aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca ucuccccugu      900

gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau cguggguggu      960

acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu aagguucagu     1020

cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag gucaaucucu     1080

gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu aaaacagacg     1140

uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc aagaccaaau     1200

guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga ugcgauuaug     1260

ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu guuaacaagc     1320

aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac gacccauugg     1380

uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag aucaaccagu     1440

cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc ggcaagagca     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaucccuca     1560

ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc cugaguaaag     1620

accaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1993
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  1993
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc cugagcaagg     1620

accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1994
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  1994
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc caccuggagg      420

gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc gugucucucu      480

ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac auugauaaac      540

aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc gugaacgcug      660

gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc agccugauca      720

acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug cagaucguga      780

gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc uaugugguuc      840

aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg agcccccucu      900

gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau cgcggcuggu      960

acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu aaggugcaga     1020

gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag gugaaucucu     1080

gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc aaaacagacg     1140

ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc aagacaaaau     1200

guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga ugcgauuaug     1260

uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu guuaacaagc     1320

aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac gacccccucg     1380

ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag auuaaccagu     1440

cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu ggcaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucccuga     1560

ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc cuuucuaaag     1620

accaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1995
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  1995
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uauuaauacu aaaagcaaac gcuauaacaa caauacuaac agcagucaca uucugcuuug      120

caucaggcca aaacaucaca gaagaauuuu accaaucaac augcuccgcc guaucgaaag      180

gauaccuagg cgcauuaaga accggauggu auacaucagu cauaacaauu gaacuaucua      240

acauaaaaga aaacaaaugu aacggcacag augccaaagu aaaacucauc aaacaagaau      300

uagauaaaua caaaaacgca gucacugaac uacaacucuu aaugcaauca acaccugcaa      360

caggaucagg aucagcaaua ugcucaggag uagccguaug uaaaguacua caccuagaag      420

gagaagucaa caaaauaaaa ucagcccucc uaaguacaaa caaagcuguc guaucacuau      480

ccaauggugu uucaguacua acuuucaaag uucuagaccu aaaaaacuac auagacaaac      540

aacuacuacc aauacuaaau aaacaaaguu guucuauacc caacauagaa accgucauag      600

aauuucaaca aaaaaauaau agacuccuag aaauaacaag agaauuuuca guuaacgcag      660

guguaacaac cccaguaucc accuauaugc uaacaaauuc agaauuacuu ucccuaauca      720

acgacaugcc cauaacaaau gaccaaaaaa aauuaauguc aaacaacguc caaauaguuc      780

gucaacaauc auauucaaua augugcauaa uaaaagaaga agucuuagcc uacguaguac      840

aacuuccccu uuauggaguu aucgacacac ccugcuggaa acuccacacu ucaccacuau      900

guacuacaaa cacaaaagaa ggauccaaca ucugccucac aagaaccgau cgaggauggu      960

acugugauaa cgccggaucc gucucauucu ucccacaagc agaaacaugc aaaguacaau     1020

caaacagagu auuuugcgac acaaugaacu cccucacauu accuucugaa guaaaccuau     1080

guaauguaga cauauucaac cccaaauacg auugcaaaau aaugacauca aagacagaug     1140

uaucaucaag ugucaucaca ucccuaggag caauugucuc auguuauggu aaaacaaaau     1200

gcaccgcauc aaauaaaaac agaggcauaa uaaaaaccuu cucaaacggu ugugacuacg     1260

uauccaauaa aggcgucgac acaguaucag uagguaacac auuauauugu guaaacaaac     1320

aagaaggaca gucccuauau guaaaaggag aaccaauaau caacuucuac gacccacuug     1380

uuuucccuuc ugaugaauuu gacgcaagua uaucacaagu aaaugaaaaa aucaaucaau     1440

cacuagccuu uauaagaaaa ucagaugaau uauuacacaa cguaaacgcc ggaaaaucaa     1500

caaccaacau aaugauaacc acaauaauaa ucgucauaau agucauccua cuaucacuca     1560

uagcaguugg acuccuacua uacugcaaag cacgaucaac accaguaaca uuauccaaag     1620

accaacuaag ugguaucaau aacaucgccu uuucaaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1996
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  1996
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccuaauccu caaagccaac gcaaucacca caauccucac ugccgucacc uucugcuucg      120

ccuccggcca aaacauaaca gaagaauuuu accaaucaac cuguucagcg gucuccaaag      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu gaucaccaua gaacucucca      240

acaucaagga aaacaaaugc aacggcaccg acgcgaaggu caaacuuauu aaacaagaac      300

ucgacaaaua caaaaacgca gucaccgaac uacaacuccu aaugcagucc acgccagcca      360

ccggcucugg cucagccaua ugcuccggug uggccguaug caaaguccua caccucgaag      420

gagaagucaa caaaauaaaa uccgcccuac uguccacaaa caaggccgua gucucccucu      480

caaacggcgu cucaguacuc accuucaaag uccuagaccu caagaacuac aucgacaaac      540

aacuccuacc cauacuaaac aaacaauccu gcucaauccc caacaucgaa accguaauag      600

aauuucaaca aaaaaacaac agacuccugg agaucacccg ggaauuuucc guaaacgccg      660

gagucacaac acccgucuca accuacaugc uaacgaacuc agagcuccuc ucacuuauca      720

acgacaugcc cauaacaaac gaccaaaaaa aacucauguc caacaacgug caaaucgucc      780

gacaacaauc cuacuccauc augugcauca uuaaagaaga aguccucgca uacguagucc      840

agcucccccu cuacggcguc auagacaccc ccugcuggaa acuacacaca ucaccccucu      900

gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccgcaccgac cgaggcuggu      960

acugcgauaa cgccggcagc gucuccuucu ucccccaagc agaaaccugc aagguccaau     1020

ccaaccgagu uuucugcgac acuaugaacu cgcucacccu ccccuccgaa gucaaccucu     1080

gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucc aagaccgacg     1140

uauccuccuc cgucaucacc ucccuaggcg ccauaguaag uugcuacggc aaaaccaagu     1200

gcacagcaag caacaaaaac cgaggaauaa ucaaaaccuu cuccaacggc ugcgacuacg     1260

uauccaacaa gggcgucgac accguauccg uagggaacac ccuuuacugc guaaacaaac     1320

aagaaggaca aucacucuac guaaaaggcg aacccauaau caacuucuac gacccccucg     1380

uauuucccuc cgacgaauuu gacgcaucaa ucucacaggu caacgaaaaa auaaaccaau     1440

cgcuagcauu caucagaaaa ucagacgaac uccuacacaa cgucaacgca ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgucauaau cgucauacua cucucacuca     1560

uagcagucgg ccuccuccua uacuguaaag caaggucgac cccagucacc cuauccaaag     1620

accaacuaag cggcaucaac aacaucgcgu ucucaaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  1997
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1) R6771

<400>  1997
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccggagc     1560

acgcccguca cccuguccaa ggaccagcug agcggcauca acaacaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  1998
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt1)

<400>  1998
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucugcuccgg cguggccgug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcgcu gcuguccacc      420

aacaaggccg uggucagccu cuccaacggc gugagcgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcaguc cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcucaccaac      660

uccgagcugc ugagccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccg cuguacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggguccaa caucugccug      900

acccgcaccg accggggcug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cucccguccg aggucaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccucuacu gcgucaacaa gcaggagggc cagagccugu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccccu gguguucccg agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cgggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug gggcuccugc uguacugcaa ggcccggucc     1560

acccccguga cccugagcaa ggaccagcuc uccggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  1999
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt2)

<400>  1999
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcucc     1560

acccccguca cccucuccaa ggaccagcuc uccggcauca acaacaucgc cuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2000
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt3)

<400>  2000
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua uauguucagg cguggcaguc      360

ugcaaggugu ugcaccucga gggugaaguu aacaaaauca agagcgcccu gcugaguacg      420

aauaaagcug uggucucccu cucuaacggg gugagcguau uaacuuuuaa gguucuggac      480

cuuaagaauu acauugauaa acaauugcug ccuauccuaa acaagcaguc cuguucaauu      540

ccaaauaucg agaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuua gugucaacgc cggagugacu accccgguga gcacauauau gcuuaccaau      660

ucugaacugu ugucccucau caacgacaug cccauuacga acgaucaaaa gaaacugaug      720

ucaaauaacg uccagaucgu ucgccagcag agcuacagua ucaugugcau uauaaaggag      780

gaaguguuag cguauguagu gcaacugccu cucuacggcg ucaucgacac uccauguugg      840

aaacuucaua caucuccccu gugcaccacu aauacaaagg agggcuccaa cauuuguuug      900

acccgaacgg aucgugggug guacugcgac aaugcaggaa gcgugucguu cuuuccucag      960

gccgaaaccu guaagguuca gucuaacaga guguucugcg auacaaugaa cucccuaacu     1020

cugccaucag aggucaaucu cugcaaugug gacaucuuua accccaaaua ugauuguaag     1080

auaaugacca guaaaacaga cguaagcucc ucuguuauua cuagccuggg ugcuaucgug     1140

ucaugcuacg gcaagaccaa auguacagcc aguaauaaga acagggggau cauuaagacc     1200

uucuccaaug gaugcgauua ugucagcaac aaaggcgugg acacugucuc uguggguaau     1260

acgcuuuacu guguuaacaa gcaagagggg cagucacugu augugaaagg agaaccuauc     1320

auuaacuuuu acgacccauu gguauucccg agugaugagu uugacgcaag cauaucccag     1380

gucaaugaaa agaucaacca gucucucgcu uucauucgga aaucggauga gcuguuacac     1440

aaugugaacg ccggcaagag cacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaucccu caucgcgguc ggccugcuuu uguauugcaa ggcccgcuca     1560

acacccguga cccugaguaa agaccaacuc ucugggauaa acaauaucgc auucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2001
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt4)

<400>  2001
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagaagc     1560

acccccguga cccugagcaa ggaccagcug agcggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2002
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt5)

<400>  2002
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaauaaau gcaacgggac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua uuuguagcgg ggucgccgug      360

ugcaagguuc uccaccugga gggagaagug aacaaaauca aguccgcgcu ucugagcacc      420

aauaaagccg ucgugucucu cuccaacggc guuagcgugc ugacauuuaa gguccuugac      480

cugaagaauu acauugauaa acaacuccug ccuauccuga acaagcaguc uuguuccauu      540

ccgaauaucg agaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuua gcgugaacgc uggcgucaca acccccguuu cuacauauau gcuuaccaau      660

uccgaacugc ucagccugau caacgacaug ccuauuacca acgaucaaaa gaaacuuaug      720

uccaauaacg ugcagaucgu gagacagcag ucuuacagca uuaugugcau cauuaaggag      780

gaaguccugg ccuauguggu ucaacucccc cuguacgggg ugaucgacac accuuguugg      840

aaacugcaua cgagcccccu cugcaccaca aauaccaagg agggauccaa caucugucug      900

acacggaccg aucgcggcug guacugcgac aaugcugggu cugucuccuu cuuuccucag      960

gccgaaacgu guaaggugca gagcaacaga guuuucugcg auacaaugaa cucucuuacc     1020

cugccgagcg aggugaaucu cugcaauguc gacauuuuua accccaaaua ugauuguaag     1080

aucaugaccu ccaaaacaga cgugucuagc uccgucauua ccagccuggg agcgaucgug     1140

ucuugcuacg gcaagacaaa auguacggcc uccaauaaga accgggggau uaucaagacc     1200

uucagcaaug gaugcgauua uguuucuaac aaaggcgugg acacagucuc cgugggcaau     1260

acccuuuacu guguuaacaa gcaagagggg cagagccugu augugaaagg agaaccuauc     1320

auuaacuuuu acgacccccu cgucuucccu uccgaugagu uugacgcuuc uaucagccag     1380

gugaaugaaa agauuaacca gucccuggcc uucauccgca aaucugauga gcugcuccac     1440

aaugugaacg cuggcaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucccu gaucgccgug gggcuccugc uguauugcaa ggccagaagc     1560

acacccguga cccuuucuaa agaccaacuc uccggaauua acaauaucgc uuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2003
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt6)

<400>  2003
gggagaaagc uuaccaugga acuauuaaua cuaaaagcaa acgcuauaac aacaauacua       60

acagcaguca cauucugcuu ugcaucaggc caaaacauca cagaagaauu uuaccaauca      120

acaugcuccg ccguaucgaa aggauaccua ggcgcauuaa gaaccggaug guauacauca      180

gucauaacaa uugaacuauc uaacauaaaa gaaaacaaau guaacggcac agaugccaaa      240

guaaaacuca ucaaacaaga auuagauaaa uacaaaaacg cagucacuga acuacaacuc      300

uuaaugcaau caacaccugc aacaggauca ggaucagcaa uaugcucagg aguagccgua      360

uguaaaguac uacaccuaga aggagaaguc aacaaaauaa aaucagcccu ccuaaguaca      420

aacaaagcug ucguaucacu auccaauggu guuucaguac uaacuuucaa aguucuagac      480

cuaaaaaacu acauagacaa acaacuacua ccaauacuaa auaaacaaag uuguucuaua      540

cccaacauag aaaccgucau agaauuucaa caaaaaaaua auagacuccu agaaauaaca      600

agagaauuuu caguuaacgc agguguaaca accccaguau ccaccuauau gcuaacaaau      660

ucagaauuac uuucccuaau caacgacaug cccauaacaa augaccaaaa aaaauuaaug      720

ucaaacaacg uccaaauagu ucgucaacaa ucauauucaa uaaugugcau aauaaaagaa      780

gaagucuuag ccuacguagu acaacuuccc cuuuauggag uuaucgacac acccugcugg      840

aaacuccaca cuucaccacu auguacuaca aacacaaaag aaggauccaa caucugccuc      900

acaagaaccg aucgaggaug guacugugau aacgccggau ccgucucauu cuucccacaa      960

gcagaaacau gcaaaguaca aucaaacaga guauuuugcg acacaaugaa cucccucaca     1020

uuaccuucug aaguaaaccu auguaaugua gacauauuca accccaaaua cgauugcaaa     1080

auaaugacau caaagacaga uguaucauca agugucauca caucccuagg agcaauuguc     1140

ucauguuaug guaaaacaaa augcaccgca ucaaauaaaa acagaggcau aauaaaaacc     1200

uucucaaacg guugugacua cguauccaau aaaggcgucg acacaguauc aguagguaac     1260

acauuauauu guguaaacaa acaagaagga cagucccuau auguaaaagg agaaccaaua     1320

aucaacuucu acgacccacu uguuuucccu ucugaugaau uugacgcaag uauaucacaa     1380

guaaaugaaa aaaucaauca aucacuagcc uuuauaagaa aaucagauga auuauuacac     1440

aacguaaacg ccggaaaauc aacaaccaac auaaugauaa ccacaauaau aaucgucaua     1500

auagucaucc uacuaucacu cauagcaguu ggacuccuac uauacugcaa agcacgauca     1560

acaccaguaa cauuauccaa agaccaacua agugguauca auaacaucgc cuuuucaaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2004
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut1 (opt11)

<400>  2004
gggagaaagc uuaccaugga acuccuaauc cucaaagcca acgcaaucac cacaauccuc       60

acugccguca ccuucugcuu cgccuccggc caaaacauaa cagaagaauu uuaccaauca      120

accuguucag cggucuccaa aggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gugaucacca uagaacucuc caacaucaag gaaaacaaau gcaacggcac cgacgcgaag      240

gucaaacuua uuaaacaaga acucgacaaa uacaaaaacg cagucaccga acuacaacuc      300

cuaaugcagu ccacgccagc caccggcucu ggcucagcca uaugcuccgg uguggccgua      360

ugcaaagucc uacaccucga aggagaaguc aacaaaauaa aauccgcccu acuguccaca      420

aacaaggccg uagucucccu cucaaacggc gucucaguac ucaccuucaa aguccuagac      480

cucaagaacu acaucgacaa acaacuccua cccauacuaa acaaacaauc cugcucaauc      540

cccaacaucg aaaccguaau agaauuucaa caaaaaaaca acagacuccu ggagaucacc      600

cgggaauuuu ccguaaacgc cggagucaca acacccgucu caaccuacau gcuaacgaac      660

ucagagcucc ucucacuuau caacgacaug cccauaacaa acgaccaaaa aaaacucaug      720

uccaacaacg ugcaaaucgu ccgacaacaa uccuacucca ucaugugcau cauuaaagaa      780

gaaguccucg cauacguagu ccagcucccc cucuacggcg ucauagacac ccccugcugg      840

aaacuacaca caucaccccu cugcacaaca aacaccaaag aaggcuccaa caucugccuc      900

acccgcaccg accgaggcug guacugcgau aacgccggca gcgucuccuu cuucccccaa      960

gcagaaaccu gcaaggucca auccaaccga guuuucugcg acacuaugaa cucgcucacc     1020

cuccccuccg aagucaaccu cugcaacguc gacauuuuca accccaaaua cgacugcaaa     1080

aucaugaccu ccaagaccga cguauccucc uccgucauca ccucccuagg cgccauagua     1140

aguugcuacg gcaaaaccaa gugcacagca agcaacaaaa accgaggaau aaucaaaacc     1200

uucuccaacg gcugcgacua cguauccaac aagggcgucg acaccguauc cguagggaac     1260

acccuuuacu gcguaaacaa acaagaagga caaucacucu acguaaaagg cgaacccaua     1320

aucaacuucu acgacccccu cguauuuccc uccgacgaau uugacgcauc aaucucacag     1380

gucaacgaaa aaauaaacca aucgcuagca uucaucagaa aaucagacga acuccuacac     1440

aacgucaacg caggcaagag caccaccaac aucaugauca ccaccaucau caucgucaua     1500

aucgucauac uacucucacu cauagcaguc ggccuccucc uauacuguaa agcaaggucg     1560

accccaguca cccuauccaa agaccaacua agcggcauca acaacaucgc guucucaaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2005
<211>  514
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2005

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg 
        


<210>  2006
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2006
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc gguga                     1545


<210>  2007
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2007
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucugc uccggcgugg ccgugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcgcugcugu ccaccaacaa ggccgugguc      420

agccucucca acggcgugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccgcugua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      900

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu cuacugcguc     1260

aacaagcagg agggccagag ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguga                     1545


<210>  2008
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2008
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuga                     1545


<210>  2009
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2009
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuauaugu ucaggcgugg cagucugcaa gguguugcac      360

cucgagggug aaguuaacaa aaucaagagc gcccugcuga guacgaauaa agcugugguc      420

ucccucucua acggggugag cguauuaacu uuuaagguuc uggaccuuaa gaauuacauu      480

gauaaacaau ugcugccuau ccuaaacaag caguccuguu caauuccaaa uaucgagacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuaguguc      600

aacgccggag ugacuacccc ggugagcaca uauaugcuua ccaauucuga acuguugucc      660

cucaucaacg acaugcccau uacgaacgau caaaagaaac ugaugucaaa uaacguccag      720

aucguucgcc agcagagcua caguaucaug ugcauuauaa aggaggaagu guuagcguau      780

guagugcaac ugccucucua cggcgucauc gacacuccau guuggaaacu ucauacaucu      840

ccccugugca ccacuaauac aaaggagggc uccaacauuu guuugacccg aacggaucgu      900

gggugguacu gcgacaaugc aggaagcgug ucguucuuuc cucaggccga aaccuguaag      960

guucagucua acagaguguu cugcgauaca augaacuccc uaacucugcc aucagagguc     1020

aaucucugca auguggacau cuuuaacccc aaauaugauu guaagauaau gaccaguaaa     1080

acagacguaa gcuccucugu uauuacuagc cugggugcua ucgugucaug cuacggcaag     1140

accaaaugua cagccaguaa uaagaacagg gggaucauua agaccuucuc caauggaugc     1200

gauuauguca gcaacaaagg cguggacacu gucucugugg guaauacgcu uuacuguguu     1260

aacaagcaag aggggcaguc acuguaugug aaaggagaac cuaucauuaa cuuuuacgac     1320

ccauugguau ucccgaguga ugaguuugac gcaagcauau cccaggucaa ugaaaagauc     1380

aaccagucuc ucgcuuucau ucggaaaucg gaugagcugu uacacaaugu gaacgccggc     1440

aagagcacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

ucccucaucg cggucggccu gcuuuuguau ugcaaggccc gcuga                     1545


<210>  2010
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2010
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gauga                     1545


<210>  2011
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2011
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagaa uaaaugcaac gggaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuauuugu agcggggucg ccgugugcaa gguucuccac      360

cuggagggag aagugaacaa aaucaagucc gcgcuucuga gcaccaauaa agccgucgug      420

ucucucucca acggcguuag cgugcugaca uuuaaggucc uugaccugaa gaauuacauu      480

gauaaacaac uccugccuau ccugaacaag cagucuuguu ccauuccgaa uaucgagacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      600

aacgcuggcg ucacaacccc cguuucuaca uauaugcuua ccaauuccga acugcucagc      660

cugaucaacg acaugccuau uaccaacgau caaaagaaac uuauguccaa uaacgugcag      720

aucgugagac agcagucuua cagcauuaug ugcaucauua aggaggaagu ccuggccuau      780

gugguucaac ucccccugua cggggugauc gacacaccuu guuggaaacu gcauacgagc      840

ccccucugca ccacaaauac caaggaggga uccaacaucu gucugacacg gaccgaucgc      900

ggcugguacu gcgacaaugc ugggucuguc uccuucuuuc cucaggccga aacguguaag      960

gugcagagca acagaguuuu cugcgauaca augaacucuc uuacccugcc gagcgaggug     1020

aaucucugca augucgacau uuuuaacccc aaauaugauu guaagaucau gaccuccaaa     1080

acagacgugu cuagcuccgu cauuaccagc cugggagcga ucgugucuug cuacggcaag     1140

acaaaaugua cggccuccaa uaagaaccgg gggauuauca agaccuucag caauggaugc     1200

gauuauguuu cuaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuguguu     1260

aacaagcaag aggggcagag ccuguaugug aaaggagaac cuaucauuaa cuuuuacgac     1320

ccccucgucu ucccuuccga ugaguuugac gcuucuauca gccaggugaa ugaaaagauu     1380

aaccaguccc uggccuucau ccgcaaaucu gaugagcugc uccacaaugu gaacgcuggc     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucccugaucg ccguggggcu ccugcuguau ugcaaggcca gauga                     1545


<210>  2012
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2012
auggaacuac ucaucuuaaa agcaaacgca auaacaacua uucuaaccgc aguaacauuu       60

uguuucgcau caggacaaaa cauaaccgaa gaauuuuacc aaucaacaug uuccgcaguu      120

ucaaaaggau acuuaggcgc acuaagaaca ggcugguaca ccuccgugau aacaauagaa      180

uuaucaaaca uaaaagaaaa caaauguaau ggaacugacg ccaaaguaaa acuaauaaaa      240

caagaacuag acaaauauaa aaacgcagua acugaacuac aauuacuaau gcaauccacc      300

ccagcaacag gcucaggcuc agcaauuugc uccggagucg cugucugcaa aguacuacau      360

cuugaaggcg aagucaauaa aauaaaauca gcacuucuau caacaaacaa agcaguaguc      420

ucacuaucaa acggaguauc aguacuaaca uuuaaaguau uagaucuaaa aaacuauaua      480

gauaaacaac uacuacccau acucaauaaa caauccuguu caauaccaaa uauagaaacc      540

guaauagaau uucaacaaaa aaacaaucga cuauuagaaa ucacccgaga auuuucaguc      600

aaugcaggcg uaacaacacc aguaucaacc uacauguuaa ccaacuccga acuacuaucc      660

cucauaaacg acaugccaau aacaaacgau caaaaaaaac uaauguccaa caacguacaa      720

auagucagac aacaaucuua uucaauaaug ugcaucauaa aagaagaagu ucuagccuac      780

guaguucaac uuccauuaua cggcguaauu gauacaccau gcuggaaacu acacacaucc      840

ccacuaugua caacaaacac aaaagaagga ucaaacaucu gcuuaacuag aacagacaga      900

ggaugguacu gcgacaacgc aggaucaguc ucauucuuuc cacaagcaga aacaugcaag      960

guccaaucaa acagaguauu cugcgacaca augaacuccu uaacacuacc aucugaagua     1020

aaccuaugua auguagacau auuuaaccca aaauacgacu gcaaaauaau gaccucaaaa     1080

acagacguau ccucaucagu aauuacaagc cucggagcca uaguaucaug cuacggaaaa     1140

acaaaaugua cagcaucaaa caaaaacaga ggaauaauaa aaacguucuc caacggaugc     1200

gacuauguau caaacaaagg cguagacaca guaucagucg gaaauacccu uuacugcgua     1260

aacaaacaag aaggccaaag ucuauacgua aaaggagagc caauaauaaa cuuuuaugac     1320

ccccuuguau ucccaucuga cgaauuugau gcaucaauau cccaagucaa cgaaaaaauc     1380

aaccaaucau uagccuuuau uagaaaaagu gacgaacuau uacacaacgu uaaugcaggg     1440

aaaucaacaa caaauauaau gauuacaacc auaauuauag uuaucauagu uauacuacuc     1500

ucacuaaucg caguaggauu acuauuauac ugcaaagcaa gauaa                     1545


<210>  2013
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut1

<400>  2013
auggaacuac ucauccuaaa agccaacgca aucacaacca uacuuacagc uguuaccuuc       60

ugcuucgcau ccggccaaaa uaucaccgaa gaguucuacc aaucaaccug cuccgccguc      120

agcaaaggau accucggcgc ccuccgaacc ggaugguaca cuucugucau cacaaucgaa      180

cucuccaaca ucaaagaaaa caaaugcaac gguaccgacg cgaaagucaa acucaucaaa      240

caagaacuag acaaguacaa aaacgccguc accgaacugc aacuccucau gcaauccaca      300

ccagcaacgg gaucaggauc cgccaucugc ucaggcgucg ccgucugcaa aguccugcac      360

cuagaaggag aaguaaacaa aauuaaaucc gcccuacucu ccaccaacaa agcagucguc      420

ucacuaucca acggcgucuc cguccucacc uuuaaggucc ucgaccucaa aaauuauaua      480

gacaaacaac uccuccccau ccuaaacaaa caaucaugcu ccauccccaa cauagaaacc      540

gucaucgaau uucaacagaa aaacaaccga cucuuagaaa uuacccgcga guucagcguc      600

aacgccggag ucaccacacc cgucucaacc uacaugcuca ccaacucaga acuccucuca      660

cuaaucaaug auaugcccau cacaaacgac caaaagaaac ucauguccaa caacguacaa      720

aucguucgcc aacaaagcua cuccaucaug uguaucauua aagaagaagu ccucgccuac      780

gucguccaac uuccgcucua cggcguaauc gacacccccu gcuggaaacu ucacaccucg      840

ccccucugca ccacaaacac caaagaaggc uccaacaucu gccuaacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc ucauuuuucc cccaggcgga gaccugcaaa      960

guccaaucca accgcgucuu cugcgacacc augaacucuc uuacccuccc aucagaagua     1020

aaccucugca acgucgacau cuuuaacccc aaauacgauu gcaagauaau gaccuccaaa     1080

acagacgucu caucguccgu caucaccucc cuaggagcua ucgucuccug cuacggcaag     1140

accaaaugca ccgcuuccaa caaaaaccgc ggcaucauca aaaccuucuc caacgggugc     1200

gacuacgucu cuaacaaagg cguggacaca guauccguag gaaacacacu guacugcgua     1260

aacaaacaag agggccaauc gcuuuacguc aaaggcgagc caauuaucaa cuucuacgac     1320

ccgcucgucu ucccaucaga cgaguucgac gcauccaucu cccaagucaa cgagaaaauc     1380

aaucaguccc ucgccuucau acgcaaaucc gacgaacucc uacauaacgu aaacgccggc     1440

aaaucuacca caaacaucau gaucacaacc aucaucaucg uaaucaucgu cauccuucuc     1500

ucgcucaucg ccguaggacu gcuacuuuac ugcaaggccc gcuaa                     1545


<210>  2014
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2014
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2015
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2015
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2016
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2016
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2017
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2017
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2018
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2018
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2019
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2019
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2020
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2020
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc      120

uaaccgcagu aacauuuugu uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau      180

caacauguuc cgcaguuuca aaaggauacu uaggcgcacu aagaacaggc ugguacaccu      240

ccgugauaac aauagaauua ucaaacauaa aagaaaacaa auguaaugga acugacgcca      300

aaguaaaacu aauaaaacaa gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau      360

uacuaaugca auccacccca gcaacaggcu caggcucagc aauuugcucc ggagucgcug      420

ucugcaaagu acuacaucuu gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa      480

caaacaaagc aguagucuca cuaucaaacg gaguaucagu acuaacauuu aaaguauuag      540

aucuaaaaaa cuauauagau aaacaacuac uacccauacu caauaaacaa uccuguucaa      600

uaccaaauau agaaaccgua auagaauuuc aacaaaaaaa caaucgacua uuagaaauca      660

cccgagaauu uucagucaau gcaggcguaa caacaccagu aucaaccuac auguuaacca      720

acuccgaacu acuaucccuc auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua gucagacaac aaucuuauuc aauaaugugc aucauaaaag      840

aagaaguucu agccuacgua guucaacuuc cauuauacgg cguaauugau acaccaugcu      900

ggaaacuaca cacaucccca cuauguacaa caaacacaaa agaaggauca aacaucugcu      960

uaacuagaac agacagagga ugguacugcg acaacgcagg aucagucuca uucuuuccac     1020

aagcagaaac augcaagguc caaucaaaca gaguauucug cgacacaaug aacuccuuaa     1080

cacuaccauc ugaaguaaac cuauguaaug uagacauauu uaacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguauccu caucaguaau uacaagccuc ggagccauag     1200

uaucaugcua cggaaaaaca aaauguacag caucaaacaa aaacagagga auaauaaaaa     1260

cguucuccaa cggaugcgac uauguaucaa acaaaggcgu agacacagua ucagucggaa     1320

auacccuuua cugcguaaac aaacaagaag gccaaagucu auacguaaaa ggagagccaa     1380

uaauaaacuu uuaugacccc cuuguauucc caucugacga auuugaugca ucaauauccc     1440

aagucaacga aaaaaucaac caaucauuag ccuuuauuag aaaaagugac gaacuauuac     1500

acaacguuaa ugcagggaaa ucaacaacaa auauaaugau uacaaccaua auuauaguua     1560

ucauaguuau acuacucuca cuaaucgcag uaggauuacu auuauacugc aaagcaagau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2021
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2021
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc caacgcaauc acaaccauac      120

uuacagcugu uaccuucugc uucgcauccg gccaaaauau caccgaagag uucuaccaau      180

caaccugcuc cgccgucagc aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu      240

cugucaucac aaucgaacuc uccaacauca aagaaaacaa augcaacggu accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aguacaaaaa cgccgucacc gaacugcaac      360

uccucaugca auccacacca gcaacgggau caggauccgc caucugcuca ggcgucgccg      420

ucugcaaagu ccugcaccua gaaggagaag uaaacaaaau uaaauccgcc cuacucucca      480

ccaacaaagc agucgucuca cuauccaacg gcgucuccgu ccucaccuuu aagguccucg      540

accucaaaaa uuauauagac aaacaacucc uccccauccu aaacaaacaa ucaugcucca      600

uccccaacau agaaaccguc aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua      660

cccgcgaguu cagcgucaac gccggaguca ccacacccgu cucaaccuac augcucacca      720

acucagaacu ccucucacua aucaaugaua ugcccaucac aaacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgccaac aaagcuacuc caucaugugu aucauuaaag      840

aagaaguccu cgccuacguc guccaacuuc cgcucuacgg cguaaucgac acccccugcu      900

ggaaacuuca caccucgccc cucugcacca caaacaccaa agaaggcucc aacaucugcc      960

uaacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucuca uuuuuccccc     1020

aggcggagac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucucuua     1080

cccucccauc agaaguaaac cucugcaacg ucgacaucuu uaaccccaaa uacgauugca     1140

agauaaugac cuccaaaaca gacgucucau cguccgucau caccucccua ggagcuaucg     1200

ucuccugcua cggcaagacc aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa     1260

ccuucuccaa cgggugcgac uacgucucua acaaaggcgu ggacacagua uccguaggaa     1320

acacacugua cugcguaaac aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa     1380

uuaucaacuu cuacgacccg cucgucuucc caucagacga guucgacgca uccaucuccc     1440

aagucaacga gaaaaucaau cagucccucg ccuucauacg caaauccgac gaacuccuac     1500

auaacguaaa cgccggcaaa ucuaccacaa acaucaugau cacaaccauc aucaucguaa     1560

ucaucgucau ccuucucucg cucaucgccg uaggacugcu acuuuacugc aaggcccgcu     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2022
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2022
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2023
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2023
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2024
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2024
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2025
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2025
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2026
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2026
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2027
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2027
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2028
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2028
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau cuuaaaagca      120

aacgcaauaa caacuauucu aaccgcagua acauuuuguu ucgcaucagg acaaaacaua      180

accgaagaau uuuaccaauc aacauguucc gcaguuucaa aaggauacuu aggcgcacua      240

agaacaggcu gguacaccuc cgugauaaca auagaauuau caaacauaaa agaaaacaaa      300

uguaauggaa cugacgccaa aguaaaacua auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacug aacuacaauu acuaaugcaa uccaccccag caacaggcuc aggcucagca      420

auuugcuccg gagucgcugu cugcaaagua cuacaucuug aaggcgaagu caauaaaaua      480

aaaucagcac uucuaucaac aaacaaagca guagucucac uaucaaacgg aguaucagua      540

cuaacauuua aaguauuaga ucuaaaaaac uauauagaua aacaacuacu acccauacuc      600

aauaaacaau ccuguucaau accaaauaua gaaaccguaa uagaauuuca acaaaaaaac      660

aaucgacuau uagaaaucac ccgagaauuu ucagucaaug caggcguaac aacaccagua      720

ucaaccuaca uguuaaccaa cuccgaacua cuaucccuca uaaacgacau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag ucagacaaca aucuuauuca      840

auaaugugca ucauaaaaga agaaguucua gccuacguag uucaacuucc auuauacggc      900

guaauugaua caccaugcug gaaacuacac acauccccac uauguacaac aaacacaaaa      960

gaaggaucaa acaucugcuu aacuagaaca gacagaggau gguacugcga caacgcagga     1020

ucagucucau ucuuuccaca agcagaaaca ugcaaggucc aaucaaacag aguauucugc     1080

gacacaauga acuccuuaac acuaccaucu gaaguaaacc uauguaaugu agacauauuu     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguauccuc aucaguaauu     1200

acaagccucg gagccauagu aucaugcuac ggaaaaacaa aauguacagc aucaaacaaa     1260

aacagaggaa uaauaaaaac guucuccaac ggaugcgacu auguaucaaa caaaggcgua     1320

gacacaguau cagucggaaa uacccuuuac ugcguaaaca aacaagaagg ccaaagucua     1380

uacguaaaag gagagccaau aauaaacuuu uaugaccccc uuguauuccc aucugacgaa     1440

uuugaugcau caauauccca agucaacgaa aaaaucaacc aaucauuagc cuuuauuaga     1500

aaaagugacg aacuauuaca caacguuaau gcagggaaau caacaacaaa uauaaugauu     1560

acaaccauaa uuauaguuau cauaguuaua cuacucucac uaaucgcagu aggauuacua     1620

uuauacugca aagcaagaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2029
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2029
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagcc      120

aacgcaauca caaccauacu uacagcuguu accuucugcu ucgcauccgg ccaaaauauc      180

accgaagagu ucuaccaauc aaccugcucc gccgucagca aaggauaccu cggcgcccuc      240

cgaaccggau gguacacuuc ugucaucaca aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggua ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa guacaaaaac      360

gccgucaccg aacugcaacu ccucaugcaa uccacaccag caacgggauc aggauccgcc      420

aucugcucag gcgucgccgu cugcaaaguc cugcaccuag aaggagaagu aaacaaaauu      480

aaauccgccc uacucuccac caacaaagca gucgucucac uauccaacgg cgucuccguc      540

cucaccuuua agguccucga ccucaaaaau uauauagaca aacaacuccu ccccauccua      600

aacaaacaau caugcuccau ccccaacaua gaaaccguca ucgaauuuca acagaaaaac      660

aaccgacucu uagaaauuac ccgcgaguuc agcgucaacg ccggagucac cacacccguc      720

ucaaccuaca ugcucaccaa cucagaacuc cucucacuaa ucaaugauau gcccaucaca      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgccaaca aagcuacucc      840

aucaugugua ucauuaaaga agaaguccuc gccuacgucg uccaacuucc gcucuacggc      900

guaaucgaca cccccugcug gaaacuucac accucgcccc ucugcaccac aaacaccaaa      960

gaaggcucca acaucugccu aacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucucau uuuuccccca ggcggagacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucucuuac ccucccauca gaaguaaacc ucugcaacgu cgacaucuuu     1140

aaccccaaau acgauugcaa gauaaugacc uccaaaacag acgucucauc guccgucauc     1200

accucccuag gagcuaucgu cuccugcuac ggcaagacca aaugcaccgc uuccaacaaa     1260

aaccgcggca ucaucaaaac cuucuccaac gggugcgacu acgucucuaa caaaggcgug     1320

gacacaguau ccguaggaaa cacacuguac ugcguaaaca aacaagaggg ccaaucgcuu     1380

uacgucaaag gcgagccaau uaucaacuuc uacgacccgc ucgucuuccc aucagacgag     1440

uucgacgcau ccaucuccca agucaacgag aaaaucaauc agucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca uaacguaaac gccggcaaau cuaccacaaa caucaugauc     1560

acaaccauca ucaucguaau caucgucauc cuucucucgc ucaucgccgu aggacugcua     1620

cuuuacugca aggcccgcua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2030
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2030
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2031
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2031
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2032
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2032
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2033
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2033
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2034
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2034
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2035
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2035
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2036
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2036
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucu uaaaagcaaa cgcaauaaca acuauucuaa ccgcaguaac auuuuguuuc      240

gcaucaggac aaaacauaac cgaagaauuu uaccaaucaa cauguuccgc aguuucaaaa      300

ggauacuuag gcgcacuaag aacaggcugg uacaccuccg ugauaacaau agaauuauca      360

aacauaaaag aaaacaaaug uaauggaacu gacgccaaag uaaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacugaa cuacaauuac uaaugcaauc caccccagca      480

acaggcucag gcucagcaau uugcuccgga gucgcugucu gcaaaguacu acaucuugaa      540

ggcgaaguca auaaaauaaa aucagcacuu cuaucaacaa acaaagcagu agucucacua      600

ucaaacggag uaucaguacu aacauuuaaa guauuagauc uaaaaaacua uauagauaaa      660

caacuacuac ccauacucaa uaaacaaucc uguucaauac caaauauaga aaccguaaua      720

gaauuucaac aaaaaaacaa ucgacuauua gaaaucaccc gagaauuuuc agucaaugca      780

ggcguaacaa caccaguauc aaccuacaug uuaaccaacu ccgaacuacu aucccucaua      840

aacgacaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauaguc      900

agacaacaau cuuauucaau aaugugcauc auaaaagaag aaguucuagc cuacguaguu      960

caacuuccau uauacggcgu aauugauaca ccaugcugga aacuacacac auccccacua     1020

uguacaacaa acacaaaaga aggaucaaac aucugcuuaa cuagaacaga cagaggaugg     1080

uacugcgaca acgcaggauc agucucauuc uuuccacaag cagaaacaug caagguccaa     1140

ucaaacagag uauucugcga cacaaugaac uccuuaacac uaccaucuga aguaaaccua     1200

uguaauguag acauauuuaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guauccucau caguaauuac aagccucgga gccauaguau caugcuacgg aaaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaaua auaaaaacgu ucuccaacgg augcgacuau     1380

guaucaaaca aaggcguaga cacaguauca gucggaaaua cccuuuacug cguaaacaaa     1440

caagaaggcc aaagucuaua cguaaaagga gagccaauaa uaaacuuuua ugacccccuu     1500

guauucccau cugacgaauu ugaugcauca auaucccaag ucaacgaaaa aaucaaccaa     1560

ucauuagccu uuauuagaaa aagugacgaa cuauuacaca acguuaaugc agggaaauca     1620

acaacaaaua uaaugauuac aaccauaauu auaguuauca uaguuauacu acucucacua     1680

aucgcaguag gauuacuauu auacugcaaa gcaagauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2037
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2037
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagccaa cgcaaucaca accauacuua cagcuguuac cuucugcuuc      240

gcauccggcc aaaauaucac cgaagaguuc uaccaaucaa ccugcuccgc cgucagcaaa      300

ggauaccucg gcgcccuccg aaccggaugg uacacuucug ucaucacaau cgaacucucc      360

aacaucaaag aaaacaaaug caacgguacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaagu acaaaaacgc cgucaccgaa cugcaacucc ucaugcaauc cacaccagca      480

acgggaucag gauccgccau cugcucaggc gucgccgucu gcaaaguccu gcaccuagaa      540

ggagaaguaa acaaaauuaa auccgcccua cucuccacca acaaagcagu cgucucacua      600

uccaacggcg ucuccguccu caccuuuaag guccucgacc ucaaaaauua uauagacaaa      660

caacuccucc ccauccuaaa caaacaauca ugcuccaucc ccaacauaga aaccgucauc      720

gaauuucaac agaaaaacaa ccgacucuua gaaauuaccc gcgaguucag cgucaacgcc      780

ggagucacca cacccgucuc aaccuacaug cucaccaacu cagaacuccu cucacuaauc      840

aaugauaugc ccaucacaaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgccaacaaa gcuacuccau cauguguauc auuaaagaag aaguccucgc cuacgucguc      960

caacuuccgc ucuacggcgu aaucgacacc cccugcugga aacuucacac cucgccccuc     1020

ugcaccacaa acaccaaaga aggcuccaac aucugccuaa cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucucauuu uucccccagg cggagaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucucuuaccc ucccaucaga aguaaaccuc     1200

ugcaacgucg acaucuuuaa ccccaaauac gauugcaaga uaaugaccuc caaaacagac     1260

gucucaucgu ccgucaucac cucccuagga gcuaucgucu ccugcuacgg caagaccaaa     1320

ugcaccgcuu ccaacaaaaa ccgcggcauc aucaaaaccu ucuccaacgg gugcgacuac     1380

gucucuaaca aaggcgugga cacaguaucc guaggaaaca cacuguacug cguaaacaaa     1440

caagagggcc aaucgcuuua cgucaaaggc gagccaauua ucaacuucua cgacccgcuc     1500

gucuucccau cagacgaguu cgacgcaucc aucucccaag ucaacgagaa aaucaaucag     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaua acguaaacgc cggcaaaucu     1620

accacaaaca ucaugaucac aaccaucauc aucguaauca ucgucauccu ucucucgcuc     1680

aucgccguag gacugcuacu uuacugcaag gcccgcuaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2038
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2038
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2039
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2039
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2040
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2040
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2041
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2041
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2042
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2042
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2043
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2043
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2044
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2044
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucaucuu aaaagcaaac gcaauaacaa cuauucuaac cgcaguaaca      180

uuuuguuucg caucaggaca aaacauaacc gaagaauuuu accaaucaac auguuccgca      240

guuucaaaag gauacuuagg cgcacuaaga acaggcuggu acaccuccgu gauaacaaua      300

gaauuaucaa acauaaaaga aaacaaaugu aauggaacug acgccaaagu aaaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacugaac uacaauuacu aaugcaaucc      420

accccagcaa caggcucagg cucagcaauu ugcuccggag ucgcugucug caaaguacua      480

caucuugaag gcgaagucaa uaaaauaaaa ucagcacuuc uaucaacaaa caaagcagua      540

gucucacuau caaacggagu aucaguacua acauuuaaag uauuagaucu aaaaaacuau      600

auagauaaac aacuacuacc cauacucaau aaacaauccu guucaauacc aaauauagaa      660

accguaauag aauuucaaca aaaaaacaau cgacuauuag aaaucacccg agaauuuuca      720

gucaaugcag gcguaacaac accaguauca accuacaugu uaaccaacuc cgaacuacua      780

ucccucauaa acgacaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguca gacaacaauc uuauucaaua augugcauca uaaaagaaga aguucuagcc      900

uacguaguuc aacuuccauu auacggcgua auugauacac caugcuggaa acuacacaca      960

uccccacuau guacaacaaa cacaaaagaa ggaucaaaca ucugcuuaac uagaacagac     1020

agaggauggu acugcgacaa cgcaggauca gucucauucu uuccacaagc agaaacaugc     1080

aagguccaau caaacagagu auucugcgac acaaugaacu ccuuaacacu accaucugaa     1140

guaaaccuau guaauguaga cauauuuaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uauccucauc aguaauuaca agccucggag ccauaguauc augcuacgga     1260

aaaacaaaau guacagcauc aaacaaaaac agaggaauaa uaaaaacguu cuccaacgga     1320

ugcgacuaug uaucaaacaa aggcguagac acaguaucag ucggaaauac ccuuuacugc     1380

guaaacaaac aagaaggcca aagucuauac guaaaaggag agccaauaau aaacuuuuau     1440

gacccccuug uauucccauc ugacgaauuu gaugcaucaa uaucccaagu caacgaaaaa     1500

aucaaccaau cauuagccuu uauuagaaaa agugacgaac uauuacacaa cguuaaugca     1560

gggaaaucaa caacaaauau aaugauuaca accauaauua uaguuaucau aguuauacua     1620

cucucacuaa ucgcaguagg auuacuauua uacugcaaag caagauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2045
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2045
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagccaac gcaaucacaa ccauacuuac agcuguuacc      180

uucugcuucg cauccggcca aaauaucacc gaagaguucu accaaucaac cugcuccgcc      240

gucagcaaag gauaccucgg cgcccuccga accggauggu acacuucugu caucacaauc      300

gaacucucca acaucaaaga aaacaaaugc aacgguaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaagua caaaaacgcc gucaccgaac ugcaacuccu caugcaaucc      420

acaccagcaa cgggaucagg auccgccauc ugcucaggcg ucgccgucug caaaguccug      480

caccuagaag gagaaguaaa caaaauuaaa uccgcccuac ucuccaccaa caaagcaguc      540

gucucacuau ccaacggcgu cuccguccuc accuuuaagg uccucgaccu caaaaauuau      600

auagacaaac aacuccuccc cauccuaaac aaacaaucau gcuccauccc caacauagaa      660

accgucaucg aauuucaaca gaaaaacaac cgacucuuag aaauuacccg cgaguucagc      720

gucaacgccg gagucaccac acccgucuca accuacaugc ucaccaacuc agaacuccuc      780

ucacuaauca augauaugcc caucacaaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gccaacaaag cuacuccauc auguguauca uuaaagaaga aguccucgcc      900

uacgucgucc aacuuccgcu cuacggcgua aucgacaccc ccugcuggaa acuucacacc      960

ucgccccucu gcaccacaaa caccaaagaa ggcuccaaca ucugccuaac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucucauuuu ucccccaggc ggagaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cucuuacccu cccaucagaa     1140

guaaaccucu gcaacgucga caucuuuaac cccaaauacg auugcaagau aaugaccucc     1200

aaaacagacg ucucaucguc cgucaucacc ucccuaggag cuaucgucuc cugcuacggc     1260

aagaccaaau gcaccgcuuc caacaaaaac cgcggcauca ucaaaaccuu cuccaacggg     1320

ugcgacuacg ucucuaacaa aggcguggac acaguauccg uaggaaacac acuguacugc     1380

guaaacaaac aagagggcca aucgcuuuac gucaaaggcg agccaauuau caacuucuac     1440

gacccgcucg ucuucccauc agacgaguuc gacgcaucca ucucccaagu caacgagaaa     1500

aucaaucagu cccucgccuu cauacgcaaa uccgacgaac uccuacauaa cguaaacgcc     1560

ggcaaaucua ccacaaacau caugaucaca accaucauca ucguaaucau cgucauccuu     1620

cucucgcuca ucgccguagg acugcuacuu uacugcaagg cccgcuaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2046
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2046
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2047
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2047
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2048
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2048
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2049
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2049
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2050
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2050
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2051
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2051
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2052
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2052
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu caucuuaaaa gcaaacgcaa uaacaacuau ucuaaccgca      120

guaacauuuu guuucgcauc aggacaaaac auaaccgaag aauuuuacca aucaacaugu      180

uccgcaguuu caaaaggaua cuuaggcgca cuaagaacag gcugguacac cuccgugaua      240

acaauagaau uaucaaacau aaaagaaaac aaauguaaug gaacugacgc caaaguaaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgcaguaa cugaacuaca auuacuaaug      360

caauccaccc cagcaacagg cucaggcuca gcaauuugcu ccggagucgc ugucugcaaa      420

guacuacauc uugaaggcga agucaauaaa auaaaaucag cacuucuauc aacaaacaaa      480

gcaguagucu cacuaucaaa cggaguauca guacuaacau uuaaaguauu agaucuaaaa      540

aacuauauag auaaacaacu acuacccaua cucaauaaac aauccuguuc aauaccaaau      600

auagaaaccg uaauagaauu ucaacaaaaa aacaaucgac uauuagaaau cacccgagaa      660

uuuucaguca augcaggcgu aacaacacca guaucaaccu acauguuaac caacuccgaa      720

cuacuauccc ucauaaacga caugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uagucagaca acaaucuuau ucaauaaugu gcaucauaaa agaagaaguu      840

cuagccuacg uaguucaacu uccauuauac ggcguaauug auacaccaug cuggaaacua      900

cacacauccc cacuauguac aacaaacaca aaagaaggau caaacaucug cuuaacuaga      960

acagacagag gaugguacug cgacaacgca ggaucagucu cauucuuucc acaagcagaa     1020

acaugcaagg uccaaucaaa cagaguauuc ugcgacacaa ugaacuccuu aacacuacca     1080

ucugaaguaa accuauguaa uguagacaua uuuaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguauc cucaucagua auuacaagcc ucggagccau aguaucaugc     1200

uacggaaaaa caaaauguac agcaucaaac aaaaacagag gaauaauaaa aacguucucc     1260

aacggaugcg acuauguauc aaacaaaggc guagacacag uaucagucgg aaauacccuu     1320

uacugcguaa acaaacaaga aggccaaagu cuauacguaa aaggagagcc aauaauaaac     1380

uuuuaugacc cccuuguauu cccaucugac gaauuugaug caucaauauc ccaagucaac     1440

gaaaaaauca accaaucauu agccuuuauu agaaaaagug acgaacuauu acacaacguu     1500

aaugcaggga aaucaacaac aaauauaaug auuacaacca uaauuauagu uaucauaguu     1560

auacuacucu cacuaaucgc aguaggauua cuauuauacu gcaaagcaag auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2053
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2053
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gccaacgcaa ucacaaccau acuuacagcu      120

guuaccuucu gcuucgcauc cggccaaaau aucaccgaag aguucuacca aucaaccugc      180

uccgccguca gcaaaggaua ccucggcgcc cuccgaaccg gaugguacac uucugucauc      240

acaaucgaac ucuccaacau caaagaaaac aaaugcaacg guaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaguacaaa aacgccguca ccgaacugca acuccucaug      360

caauccacac cagcaacggg aucaggaucc gccaucugcu caggcgucgc cgucugcaaa      420

guccugcacc uagaaggaga aguaaacaaa auuaaauccg cccuacucuc caccaacaaa      480

gcagucgucu cacuauccaa cggcgucucc guccucaccu uuaagguccu cgaccucaaa      540

aauuauauag acaaacaacu ccuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

auagaaaccg ucaucgaauu ucaacagaaa aacaaccgac ucuuagaaau uacccgcgag      660

uucagcguca acgccggagu caccacaccc gucucaaccu acaugcucac caacucagaa      720

cuccucucac uaaucaauga uaugcccauc acaaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucgcca acaaagcuac uccaucaugu guaucauuaa agaagaaguc      840

cucgccuacg ucguccaacu uccgcucuac ggcguaaucg acacccccug cuggaaacuu      900

cacaccucgc cccucugcac cacaaacacc aaagaaggcu ccaacaucug ccuaacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu cauuuuuccc ccaggcggag     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucucu uacccuccca     1080

ucagaaguaa accucugcaa cgucgacauc uuuaacccca aauacgauug caagauaaug     1140

accuccaaaa cagacgucuc aucguccguc aucaccuccc uaggagcuau cgucuccugc     1200

uacggcaaga ccaaaugcac cgcuuccaac aaaaaccgcg gcaucaucaa aaccuucucc     1260

aacgggugcg acuacgucuc uaacaaaggc guggacacag uauccguagg aaacacacug     1320

uacugcguaa acaaacaaga gggccaaucg cuuuacguca aaggcgagcc aauuaucaac     1380

uucuacgacc cgcucgucuu cccaucagac gaguucgacg cauccaucuc ccaagucaac     1440

gagaaaauca aucagucccu cgccuucaua cgcaaauccg acgaacuccu acauaacgua     1500

aacgccggca aaucuaccac aaacaucaug aucacaacca ucaucaucgu aaucaucguc     1560

auccuucucu cgcucaucgc cguaggacug cuacuuuacu gcaaggcccg cuaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2054
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2054
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2055
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2055
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      660

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1500

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1560

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2056
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2056
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2057
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2057
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      600

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      660

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      720

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      840

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      900

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      960

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua     1020

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc     1080

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg     1140

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1200

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1260

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1320

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1380

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1440

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1500

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1560

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1620

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1680

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1740

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2058
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2058
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2059
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2059
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      600

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      660

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      720

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      840

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      900

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      960

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug     1020

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc     1080

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc     1140

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1200

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1260

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1320

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1380

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1440

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1500

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1560

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1620

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1740

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2060
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2060
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc uaaccgcagu aacauuuugu      300

uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau caacauguuc cgcaguuuca      360

aaaggauacu uaggcgcacu aagaacaggc ugguacaccu ccgugauaac aauagaauua      420

ucaaacauaa aagaaaacaa auguaaugga acugacgcca aaguaaaacu aauaaaacaa      480

gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau uacuaaugca auccacccca      540

gcaacaggcu caggcucagc aauuugcucc ggagucgcug ucugcaaagu acuacaucuu      600

gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa caaacaaagc aguagucuca      660

cuaucaaacg gaguaucagu acuaacauuu aaaguauuag aucuaaaaaa cuauauagau      720

aaacaacuac uacccauacu caauaaacaa uccuguucaa uaccaaauau agaaaccgua      780

auagaauuuc aacaaaaaaa caaucgacua uuagaaauca cccgagaauu uucagucaau      840

gcaggcguaa caacaccagu aucaaccuac auguuaacca acuccgaacu acuaucccuc      900

auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      960

gucagacaac aaucuuauuc aauaaugugc aucauaaaag aagaaguucu agccuacgua     1020

guucaacuuc cauuauacgg cguaauugau acaccaugcu ggaaacuaca cacaucccca     1080

cuauguacaa caaacacaaa agaaggauca aacaucugcu uaacuagaac agacagagga     1140

ugguacugcg acaacgcagg aucagucuca uucuuuccac aagcagaaac augcaagguc     1200

caaucaaaca gaguauucug cgacacaaug aacuccuuaa cacuaccauc ugaaguaaac     1260

cuauguaaug uagacauauu uaacccaaaa uacgacugca aaauaaugac cucaaaaaca     1320

gacguauccu caucaguaau uacaagccuc ggagccauag uaucaugcua cggaaaaaca     1380

aaauguacag caucaaacaa aaacagagga auaauaaaaa cguucuccaa cggaugcgac     1440

uauguaucaa acaaaggcgu agacacagua ucagucggaa auacccuuua cugcguaaac     1500

aaacaagaag gccaaagucu auacguaaaa ggagagccaa uaauaaacuu uuaugacccc     1560

cuuguauucc caucugacga auuugaugca ucaauauccc aagucaacga aaaaaucaac     1620

caaucauuag ccuuuauuag aaaaagugac gaacuauuac acaacguuaa ugcagggaaa     1680

ucaacaacaa auauaaugau uacaaccaua auuauaguua ucauaguuau acuacucuca     1740

cuaaucgcag uaggauuacu auuauacugc aaagcaagau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2061
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2061
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuca uccuaaaagc caacgcaauc acaaccauac uuacagcugu uaccuucugc      300

uucgcauccg gccaaaauau caccgaagag uucuaccaau caaccugcuc cgccgucagc      360

aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu cugucaucac aaucgaacuc      420

uccaacauca aagaaaacaa augcaacggu accgacgcga aagucaaacu caucaaacaa      480

gaacuagaca aguacaaaaa cgccgucacc gaacugcaac uccucaugca auccacacca      540

gcaacgggau caggauccgc caucugcuca ggcgucgccg ucugcaaagu ccugcaccua      600

gaaggagaag uaaacaaaau uaaauccgcc cuacucucca ccaacaaagc agucgucuca      660

cuauccaacg gcgucuccgu ccucaccuuu aagguccucg accucaaaaa uuauauagac      720

aaacaacucc uccccauccu aaacaaacaa ucaugcucca uccccaacau agaaaccguc      780

aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua cccgcgaguu cagcgucaac      840

gccggaguca ccacacccgu cucaaccuac augcucacca acucagaacu ccucucacua      900

aucaaugaua ugcccaucac aaacgaccaa aagaaacuca uguccaacaa cguacaaauc      960

guucgccaac aaagcuacuc caucaugugu aucauuaaag aagaaguccu cgccuacguc     1020

guccaacuuc cgcucuacgg cguaaucgac acccccugcu ggaaacuuca caccucgccc     1080

cucugcacca caaacaccaa agaaggcucc aacaucugcc uaacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucuca uuuuuccccc aggcggagac cugcaaaguc     1200

caauccaacc gcgucuucug cgacaccaug aacucucuua cccucccauc agaaguaaac     1260

cucugcaacg ucgacaucuu uaaccccaaa uacgauugca agauaaugac cuccaaaaca     1320

gacgucucau cguccgucau caccucccua ggagcuaucg ucuccugcua cggcaagacc     1380

aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa ccuucuccaa cgggugcgac     1440

uacgucucua acaaaggcgu ggacacagua uccguaggaa acacacugua cugcguaaac     1500

aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa uuaucaacuu cuacgacccg     1560

cucgucuucc caucagacga guucgacgca uccaucuccc aagucaacga gaaaaucaau     1620

cagucccucg ccuucauacg caaauccgac gaacuccuac auaacguaaa cgccggcaaa     1680

ucuaccacaa acaucaugau cacaaccauc aucaucguaa ucaucgucau ccuucucucg     1740

cucaucgccg uaggacugcu acuuuacugc aaggcccgcu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2062
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2062
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2063
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2063
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2064
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2064
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2065
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2065
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      720

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg      960

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1020

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1080

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1140

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1380

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1440

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2066
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2066
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2067
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2067
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      720

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc      960

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1080

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1140

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1380

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1440

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2068
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2068
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc uaaccgcagu aacauuuugu      120

uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau caacauguuc cgcaguuuca      180

aaaggauacu uaggcgcacu aagaacaggc ugguacaccu ccgugauaac aauagaauua      240

ucaaacauaa aagaaaacaa auguaaugga acugacgcca aaguaaaacu aauaaaacaa      300

gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau uacuaaugca auccacccca      360

gcaacaggcu caggcucagc aauuugcucc ggagucgcug ucugcaaagu acuacaucuu      420

gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa caaacaaagc aguagucuca      480

cuaucaaacg gaguaucagu acuaacauuu aaaguauuag aucuaaaaaa cuauauagau      540

aaacaacuac uacccauacu caauaaacaa uccuguucaa uaccaaauau agaaaccgua      600

auagaauuuc aacaaaaaaa caaucgacua uuagaaauca cccgagaauu uucagucaau      660

gcaggcguaa caacaccagu aucaaccuac auguuaacca acuccgaacu acuaucccuc      720

auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      780

gucagacaac aaucuuauuc aauaaugugc aucauaaaag aagaaguucu agccuacgua      840

guucaacuuc cauuauacgg cguaauugau acaccaugcu ggaaacuaca cacaucccca      900

cuauguacaa caaacacaaa agaaggauca aacaucugcu uaacuagaac agacagagga      960

ugguacugcg acaacgcagg aucagucuca uucuuuccac aagcagaaac augcaagguc     1020

caaucaaaca gaguauucug cgacacaaug aacuccuuaa cacuaccauc ugaaguaaac     1080

cuauguaaug uagacauauu uaacccaaaa uacgacugca aaauaaugac cucaaaaaca     1140

gacguauccu caucaguaau uacaagccuc ggagccauag uaucaugcua cggaaaaaca     1200

aaauguacag caucaaacaa aaacagagga auaauaaaaa cguucuccaa cggaugcgac     1260

uauguaucaa acaaaggcgu agacacagua ucagucggaa auacccuuua cugcguaaac     1320

aaacaagaag gccaaagucu auacguaaaa ggagagccaa uaauaaacuu uuaugacccc     1380

cuuguauucc caucugacga auuugaugca ucaauauccc aagucaacga aaaaaucaac     1440

caaucauuag ccuuuauuag aaaaagugac gaacuauuac acaacguuaa ugcagggaaa     1500

ucaacaacaa auauaaugau uacaaccaua auuauaguua ucauaguuau acuacucuca     1560

cuaaucgcag uaggauuacu auuauacugc aaagcaagau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2069
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2069
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuca uccuaaaagc caacgcaauc acaaccauac uuacagcugu uaccuucugc      120

uucgcauccg gccaaaauau caccgaagag uucuaccaau caaccugcuc cgccgucagc      180

aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu cugucaucac aaucgaacuc      240

uccaacauca aagaaaacaa augcaacggu accgacgcga aagucaaacu caucaaacaa      300

gaacuagaca aguacaaaaa cgccgucacc gaacugcaac uccucaugca auccacacca      360

gcaacgggau caggauccgc caucugcuca ggcgucgccg ucugcaaagu ccugcaccua      420

gaaggagaag uaaacaaaau uaaauccgcc cuacucucca ccaacaaagc agucgucuca      480

cuauccaacg gcgucuccgu ccucaccuuu aagguccucg accucaaaaa uuauauagac      540

aaacaacucc uccccauccu aaacaaacaa ucaugcucca uccccaacau agaaaccguc      600

aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua cccgcgaguu cagcgucaac      660

gccggaguca ccacacccgu cucaaccuac augcucacca acucagaacu ccucucacua      720

aucaaugaua ugcccaucac aaacgaccaa aagaaacuca uguccaacaa cguacaaauc      780

guucgccaac aaagcuacuc caucaugugu aucauuaaag aagaaguccu cgccuacguc      840

guccaacuuc cgcucuacgg cguaaucgac acccccugcu ggaaacuuca caccucgccc      900

cucugcacca caaacaccaa agaaggcucc aacaucugcc uaacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucuca uuuuuccccc aggcggagac cugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucucuua cccucccauc agaaguaaac     1080

cucugcaacg ucgacaucuu uaaccccaaa uacgauugca agauaaugac cuccaaaaca     1140

gacgucucau cguccgucau caccucccua ggagcuaucg ucuccugcua cggcaagacc     1200

aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa ccuucuccaa cgggugcgac     1260

uacgucucua acaaaggcgu ggacacagua uccguaggaa acacacugua cugcguaaac     1320

aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa uuaucaacuu cuacgacccg     1380

cucgucuucc caucagacga guucgacgca uccaucuccc aagucaacga gaaaaucaau     1440

cagucccucg ccuucauacg caaauccgac gaacuccuac auaacguaaa cgccggcaaa     1500

ucuaccacaa acaucaugau cacaaccauc aucaucguaa ucaucgucau ccuucucucg     1560

cucaucgccg uaggacugcu acuuuacugc aaggcccgcu aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2070
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2070
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2071
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2071
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2072
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2072
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2073
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2073
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2074
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2074
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2075
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2075
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2076
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2076
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc      120

uaaccgcagu aacauuuugu uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau      180

caacauguuc cgcaguuuca aaaggauacu uaggcgcacu aagaacaggc ugguacaccu      240

ccgugauaac aauagaauua ucaaacauaa aagaaaacaa auguaaugga acugacgcca      300

aaguaaaacu aauaaaacaa gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau      360

uacuaaugca auccacccca gcaacaggcu caggcucagc aauuugcucc ggagucgcug      420

ucugcaaagu acuacaucuu gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa      480

caaacaaagc aguagucuca cuaucaaacg gaguaucagu acuaacauuu aaaguauuag      540

aucuaaaaaa cuauauagau aaacaacuac uacccauacu caauaaacaa uccuguucaa      600

uaccaaauau agaaaccgua auagaauuuc aacaaaaaaa caaucgacua uuagaaauca      660

cccgagaauu uucagucaau gcaggcguaa caacaccagu aucaaccuac auguuaacca      720

acuccgaacu acuaucccuc auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua gucagacaac aaucuuauuc aauaaugugc aucauaaaag      840

aagaaguucu agccuacgua guucaacuuc cauuauacgg cguaauugau acaccaugcu      900

ggaaacuaca cacaucccca cuauguacaa caaacacaaa agaaggauca aacaucugcu      960

uaacuagaac agacagagga ugguacugcg acaacgcagg aucagucuca uucuuuccac     1020

aagcagaaac augcaagguc caaucaaaca gaguauucug cgacacaaug aacuccuuaa     1080

cacuaccauc ugaaguaaac cuauguaaug uagacauauu uaacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguauccu caucaguaau uacaagccuc ggagccauag     1200

uaucaugcua cggaaaaaca aaauguacag caucaaacaa aaacagagga auaauaaaaa     1260

cguucuccaa cggaugcgac uauguaucaa acaaaggcgu agacacagua ucagucggaa     1320

auacccuuua cugcguaaac aaacaagaag gccaaagucu auacguaaaa ggagagccaa     1380

uaauaaacuu uuaugacccc cuuguauucc caucugacga auuugaugca ucaauauccc     1440

aagucaacga aaaaaucaac caaucauuag ccuuuauuag aaaaagugac gaacuauuac     1500

acaacguuaa ugcagggaaa ucaacaacaa auauaaugau uacaaccaua auuauaguua     1560

ucauaguuau acuacucuca cuaaucgcag uaggauuacu auuauacugc aaagcaagau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2077
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2077
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc caacgcaauc acaaccauac      120

uuacagcugu uaccuucugc uucgcauccg gccaaaauau caccgaagag uucuaccaau      180

caaccugcuc cgccgucagc aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu      240

cugucaucac aaucgaacuc uccaacauca aagaaaacaa augcaacggu accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aguacaaaaa cgccgucacc gaacugcaac      360

uccucaugca auccacacca gcaacgggau caggauccgc caucugcuca ggcgucgccg      420

ucugcaaagu ccugcaccua gaaggagaag uaaacaaaau uaaauccgcc cuacucucca      480

ccaacaaagc agucgucuca cuauccaacg gcgucuccgu ccucaccuuu aagguccucg      540

accucaaaaa uuauauagac aaacaacucc uccccauccu aaacaaacaa ucaugcucca      600

uccccaacau agaaaccguc aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua      660

cccgcgaguu cagcgucaac gccggaguca ccacacccgu cucaaccuac augcucacca      720

acucagaacu ccucucacua aucaaugaua ugcccaucac aaacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgccaac aaagcuacuc caucaugugu aucauuaaag      840

aagaaguccu cgccuacguc guccaacuuc cgcucuacgg cguaaucgac acccccugcu      900

ggaaacuuca caccucgccc cucugcacca caaacaccaa agaaggcucc aacaucugcc      960

uaacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucuca uuuuuccccc     1020

aggcggagac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucucuua     1080

cccucccauc agaaguaaac cucugcaacg ucgacaucuu uaaccccaaa uacgauugca     1140

agauaaugac cuccaaaaca gacgucucau cguccgucau caccucccua ggagcuaucg     1200

ucuccugcua cggcaagacc aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa     1260

ccuucuccaa cgggugcgac uacgucucua acaaaggcgu ggacacagua uccguaggaa     1320

acacacugua cugcguaaac aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa     1380

uuaucaacuu cuacgacccg cucgucuucc caucagacga guucgacgca uccaucuccc     1440

aagucaacga gaaaaucaau cagucccucg ccuucauacg caaauccgac gaacuccuac     1500

auaacguaaa cgccggcaaa ucuaccacaa acaucaugau cacaaccauc aucaucguaa     1560

ucaucgucau ccuucucucg cucaucgccg uaggacugcu acuuuacugc aaggcccgcu     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2078
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2078
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2079
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2079
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2080
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2080
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2081
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2081
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2082
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2082
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2083
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2083
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2084
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2084
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc      120

uaaccgcagu aacauuuugu uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau      180

caacauguuc cgcaguuuca aaaggauacu uaggcgcacu aagaacaggc ugguacaccu      240

ccgugauaac aauagaauua ucaaacauaa aagaaaacaa auguaaugga acugacgcca      300

aaguaaaacu aauaaaacaa gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau      360

uacuaaugca auccacccca gcaacaggcu caggcucagc aauuugcucc ggagucgcug      420

ucugcaaagu acuacaucuu gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa      480

caaacaaagc aguagucuca cuaucaaacg gaguaucagu acuaacauuu aaaguauuag      540

aucuaaaaaa cuauauagau aaacaacuac uacccauacu caauaaacaa uccuguucaa      600

uaccaaauau agaaaccgua auagaauuuc aacaaaaaaa caaucgacua uuagaaauca      660

cccgagaauu uucagucaau gcaggcguaa caacaccagu aucaaccuac auguuaacca      720

acuccgaacu acuaucccuc auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua gucagacaac aaucuuauuc aauaaugugc aucauaaaag      840

aagaaguucu agccuacgua guucaacuuc cauuauacgg cguaauugau acaccaugcu      900

ggaaacuaca cacaucccca cuauguacaa caaacacaaa agaaggauca aacaucugcu      960

uaacuagaac agacagagga ugguacugcg acaacgcagg aucagucuca uucuuuccac     1020

aagcagaaac augcaagguc caaucaaaca gaguauucug cgacacaaug aacuccuuaa     1080

cacuaccauc ugaaguaaac cuauguaaug uagacauauu uaacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguauccu caucaguaau uacaagccuc ggagccauag     1200

uaucaugcua cggaaaaaca aaauguacag caucaaacaa aaacagagga auaauaaaaa     1260

cguucuccaa cggaugcgac uauguaucaa acaaaggcgu agacacagua ucagucggaa     1320

auacccuuua cugcguaaac aaacaagaag gccaaagucu auacguaaaa ggagagccaa     1380

uaauaaacuu uuaugacccc cuuguauucc caucugacga auuugaugca ucaauauccc     1440

aagucaacga aaaaaucaac caaucauuag ccuuuauuag aaaaagugac gaacuauuac     1500

acaacguuaa ugcagggaaa ucaacaacaa auauaaugau uacaaccaua auuauaguua     1560

ucauaguuau acuacucuca cuaaucgcag uaggauuacu auuauacugc aaagcaagau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2085
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2085
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc caacgcaauc acaaccauac      120

uuacagcugu uaccuucugc uucgcauccg gccaaaauau caccgaagag uucuaccaau      180

caaccugcuc cgccgucagc aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu      240

cugucaucac aaucgaacuc uccaacauca aagaaaacaa augcaacggu accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aguacaaaaa cgccgucacc gaacugcaac      360

uccucaugca auccacacca gcaacgggau caggauccgc caucugcuca ggcgucgccg      420

ucugcaaagu ccugcaccua gaaggagaag uaaacaaaau uaaauccgcc cuacucucca      480

ccaacaaagc agucgucuca cuauccaacg gcgucuccgu ccucaccuuu aagguccucg      540

accucaaaaa uuauauagac aaacaacucc uccccauccu aaacaaacaa ucaugcucca      600

uccccaacau agaaaccguc aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua      660

cccgcgaguu cagcgucaac gccggaguca ccacacccgu cucaaccuac augcucacca      720

acucagaacu ccucucacua aucaaugaua ugcccaucac aaacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgccaac aaagcuacuc caucaugugu aucauuaaag      840

aagaaguccu cgccuacguc guccaacuuc cgcucuacgg cguaaucgac acccccugcu      900

ggaaacuuca caccucgccc cucugcacca caaacaccaa agaaggcucc aacaucugcc      960

uaacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucuca uuuuuccccc     1020

aggcggagac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucucuua     1080

cccucccauc agaaguaaac cucugcaacg ucgacaucuu uaaccccaaa uacgauugca     1140

agauaaugac cuccaaaaca gacgucucau cguccgucau caccucccua ggagcuaucg     1200

ucuccugcua cggcaagacc aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa     1260

ccuucuccaa cgggugcgac uacgucucua acaaaggcgu ggacacagua uccguaggaa     1320

acacacugua cugcguaaac aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa     1380

uuaucaacuu cuacgacccg cucgucuucc caucagacga guucgacgca uccaucuccc     1440

aagucaacga gaaaaucaau cagucccucg ccuucauacg caaauccgac gaacuccuac     1500

auaacguaaa cgccggcaaa ucuaccacaa acaucaugau cacaaccauc aucaucguaa     1560

ucaucgucau ccuucucucg cucaucgccg uaggacugcu acuuuacugc aaggcccgcu     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2086
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2086
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2087
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2087
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2088
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2088
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2089
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2089
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2090
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2090
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2091
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2091
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2092
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2092
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucaucuu aaaagcaaac gcaauaacaa cuauucuaac cgcaguaaca      180

uuuuguuucg caucaggaca aaacauaacc gaagaauuuu accaaucaac auguuccgca      240

guuucaaaag gauacuuagg cgcacuaaga acaggcuggu acaccuccgu gauaacaaua      300

gaauuaucaa acauaaaaga aaacaaaugu aauggaacug acgccaaagu aaaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacugaac uacaauuacu aaugcaaucc      420

accccagcaa caggcucagg cucagcaauu ugcuccggag ucgcugucug caaaguacua      480

caucuugaag gcgaagucaa uaaaauaaaa ucagcacuuc uaucaacaaa caaagcagua      540

gucucacuau caaacggagu aucaguacua acauuuaaag uauuagaucu aaaaaacuau      600

auagauaaac aacuacuacc cauacucaau aaacaauccu guucaauacc aaauauagaa      660

accguaauag aauuucaaca aaaaaacaau cgacuauuag aaaucacccg agaauuuuca      720

gucaaugcag gcguaacaac accaguauca accuacaugu uaaccaacuc cgaacuacua      780

ucccucauaa acgacaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguca gacaacaauc uuauucaaua augugcauca uaaaagaaga aguucuagcc      900

uacguaguuc aacuuccauu auacggcgua auugauacac caugcuggaa acuacacaca      960

uccccacuau guacaacaaa cacaaaagaa ggaucaaaca ucugcuuaac uagaacagac     1020

agaggauggu acugcgacaa cgcaggauca gucucauucu uuccacaagc agaaacaugc     1080

aagguccaau caaacagagu auucugcgac acaaugaacu ccuuaacacu accaucugaa     1140

guaaaccuau guaauguaga cauauuuaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uauccucauc aguaauuaca agccucggag ccauaguauc augcuacgga     1260

aaaacaaaau guacagcauc aaacaaaaac agaggaauaa uaaaaacguu cuccaacgga     1320

ugcgacuaug uaucaaacaa aggcguagac acaguaucag ucggaaauac ccuuuacugc     1380

guaaacaaac aagaaggcca aagucuauac guaaaaggag agccaauaau aaacuuuuau     1440

gacccccuug uauucccauc ugacgaauuu gaugcaucaa uaucccaagu caacgaaaaa     1500

aucaaccaau cauuagccuu uauuagaaaa agugacgaac uauuacacaa cguuaaugca     1560

gggaaaucaa caacaaauau aaugauuaca accauaauua uaguuaucau aguuauacua     1620

cucucacuaa ucgcaguagg auuacuauua uacugcaaag caagauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2093
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2093
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagccaac gcaaucacaa ccauacuuac agcuguuacc      180

uucugcuucg cauccggcca aaauaucacc gaagaguucu accaaucaac cugcuccgcc      240

gucagcaaag gauaccucgg cgcccuccga accggauggu acacuucugu caucacaauc      300

gaacucucca acaucaaaga aaacaaaugc aacgguaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaagua caaaaacgcc gucaccgaac ugcaacuccu caugcaaucc      420

acaccagcaa cgggaucagg auccgccauc ugcucaggcg ucgccgucug caaaguccug      480

caccuagaag gagaaguaaa caaaauuaaa uccgcccuac ucuccaccaa caaagcaguc      540

gucucacuau ccaacggcgu cuccguccuc accuuuaagg uccucgaccu caaaaauuau      600

auagacaaac aacuccuccc cauccuaaac aaacaaucau gcuccauccc caacauagaa      660

accgucaucg aauuucaaca gaaaaacaac cgacucuuag aaauuacccg cgaguucagc      720

gucaacgccg gagucaccac acccgucuca accuacaugc ucaccaacuc agaacuccuc      780

ucacuaauca augauaugcc caucacaaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gccaacaaag cuacuccauc auguguauca uuaaagaaga aguccucgcc      900

uacgucgucc aacuuccgcu cuacggcgua aucgacaccc ccugcuggaa acuucacacc      960

ucgccccucu gcaccacaaa caccaaagaa ggcuccaaca ucugccuaac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucucauuuu ucccccaggc ggagaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cucuuacccu cccaucagaa     1140

guaaaccucu gcaacgucga caucuuuaac cccaaauacg auugcaagau aaugaccucc     1200

aaaacagacg ucucaucguc cgucaucacc ucccuaggag cuaucgucuc cugcuacggc     1260

aagaccaaau gcaccgcuuc caacaaaaac cgcggcauca ucaaaaccuu cuccaacggg     1320

ugcgacuacg ucucuaacaa aggcguggac acaguauccg uaggaaacac acuguacugc     1380

guaaacaaac aagagggcca aucgcuuuac gucaaaggcg agccaauuau caacuucuac     1440

gacccgcucg ucuucccauc agacgaguuc gacgcaucca ucucccaagu caacgagaaa     1500

aucaaucagu cccucgccuu cauacgcaaa uccgacgaac uccuacauaa cguaaacgcc     1560

ggcaaaucua ccacaaacau caugaucaca accaucauca ucguaaucau cgucauccuu     1620

cucucgcuca ucgccguagg acugcuacuu uacugcaagg cccgcuaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2094
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2094
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2095
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2095
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2096
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2096
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2097
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2097
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2098
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2098
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2099
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2099
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2100
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2100
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau cuuaaaagca      120

aacgcaauaa caacuauucu aaccgcagua acauuuuguu ucgcaucagg acaaaacaua      180

accgaagaau uuuaccaauc aacauguucc gcaguuucaa aaggauacuu aggcgcacua      240

agaacaggcu gguacaccuc cgugauaaca auagaauuau caaacauaaa agaaaacaaa      300

uguaauggaa cugacgccaa aguaaaacua auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacug aacuacaauu acuaaugcaa uccaccccag caacaggcuc aggcucagca      420

auuugcuccg gagucgcugu cugcaaagua cuacaucuug aaggcgaagu caauaaaaua      480

aaaucagcac uucuaucaac aaacaaagca guagucucac uaucaaacgg aguaucagua      540

cuaacauuua aaguauuaga ucuaaaaaac uauauagaua aacaacuacu acccauacuc      600

aauaaacaau ccuguucaau accaaauaua gaaaccguaa uagaauuuca acaaaaaaac      660

aaucgacuau uagaaaucac ccgagaauuu ucagucaaug caggcguaac aacaccagua      720

ucaaccuaca uguuaaccaa cuccgaacua cuaucccuca uaaacgacau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag ucagacaaca aucuuauuca      840

auaaugugca ucauaaaaga agaaguucua gccuacguag uucaacuucc auuauacggc      900

guaauugaua caccaugcug gaaacuacac acauccccac uauguacaac aaacacaaaa      960

gaaggaucaa acaucugcuu aacuagaaca gacagaggau gguacugcga caacgcagga     1020

ucagucucau ucuuuccaca agcagaaaca ugcaaggucc aaucaaacag aguauucugc     1080

gacacaauga acuccuuaac acuaccaucu gaaguaaacc uauguaaugu agacauauuu     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguauccuc aucaguaauu     1200

acaagccucg gagccauagu aucaugcuac ggaaaaacaa aauguacagc aucaaacaaa     1260

aacagaggaa uaauaaaaac guucuccaac ggaugcgacu auguaucaaa caaaggcgua     1320

gacacaguau cagucggaaa uacccuuuac ugcguaaaca aacaagaagg ccaaagucua     1380

uacguaaaag gagagccaau aauaaacuuu uaugaccccc uuguauuccc aucugacgaa     1440

uuugaugcau caauauccca agucaacgaa aaaaucaacc aaucauuagc cuuuauuaga     1500

aaaagugacg aacuauuaca caacguuaau gcagggaaau caacaacaaa uauaaugauu     1560

acaaccauaa uuauaguuau cauaguuaua cuacucucac uaaucgcagu aggauuacua     1620

uuauacugca aagcaagaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2101
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2101
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagcc      120

aacgcaauca caaccauacu uacagcuguu accuucugcu ucgcauccgg ccaaaauauc      180

accgaagagu ucuaccaauc aaccugcucc gccgucagca aaggauaccu cggcgcccuc      240

cgaaccggau gguacacuuc ugucaucaca aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggua ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa guacaaaaac      360

gccgucaccg aacugcaacu ccucaugcaa uccacaccag caacgggauc aggauccgcc      420

aucugcucag gcgucgccgu cugcaaaguc cugcaccuag aaggagaagu aaacaaaauu      480

aaauccgccc uacucuccac caacaaagca gucgucucac uauccaacgg cgucuccguc      540

cucaccuuua agguccucga ccucaaaaau uauauagaca aacaacuccu ccccauccua      600

aacaaacaau caugcuccau ccccaacaua gaaaccguca ucgaauuuca acagaaaaac      660

aaccgacucu uagaaauuac ccgcgaguuc agcgucaacg ccggagucac cacacccguc      720

ucaaccuaca ugcucaccaa cucagaacuc cucucacuaa ucaaugauau gcccaucaca      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgccaaca aagcuacucc      840

aucaugugua ucauuaaaga agaaguccuc gccuacgucg uccaacuucc gcucuacggc      900

guaaucgaca cccccugcug gaaacuucac accucgcccc ucugcaccac aaacaccaaa      960

gaaggcucca acaucugccu aacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucucau uuuuccccca ggcggagacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucucuuac ccucccauca gaaguaaacc ucugcaacgu cgacaucuuu     1140

aaccccaaau acgauugcaa gauaaugacc uccaaaacag acgucucauc guccgucauc     1200

accucccuag gagcuaucgu cuccugcuac ggcaagacca aaugcaccgc uuccaacaaa     1260

aaccgcggca ucaucaaaac cuucuccaac gggugcgacu acgucucuaa caaaggcgug     1320

gacacaguau ccguaggaaa cacacuguac ugcguaaaca aacaagaggg ccaaucgcuu     1380

uacgucaaag gcgagccaau uaucaacuuc uacgacccgc ucgucuuccc aucagacgag     1440

uucgacgcau ccaucuccca agucaacgag aaaaucaauc agucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca uaacguaaac gccggcaaau cuaccacaaa caucaugauc     1560

acaaccauca ucaucguaau caucgucauc cuucucucgc ucaucgccgu aggacugcua     1620

cuuuacugca aggcccgcua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2102
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2102
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2103
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2103
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2104
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2104
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2105
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2105
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2106
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2106
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2107
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2107
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2108
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2108
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucaucuu aaaagcaaac gcaauaacaa cuauucuaac cgcaguaaca      180

uuuuguuucg caucaggaca aaacauaacc gaagaauuuu accaaucaac auguuccgca      240

guuucaaaag gauacuuagg cgcacuaaga acaggcuggu acaccuccgu gauaacaaua      300

gaauuaucaa acauaaaaga aaacaaaugu aauggaacug acgccaaagu aaaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacugaac uacaauuacu aaugcaaucc      420

accccagcaa caggcucagg cucagcaauu ugcuccggag ucgcugucug caaaguacua      480

caucuugaag gcgaagucaa uaaaauaaaa ucagcacuuc uaucaacaaa caaagcagua      540

gucucacuau caaacggagu aucaguacua acauuuaaag uauuagaucu aaaaaacuau      600

auagauaaac aacuacuacc cauacucaau aaacaauccu guucaauacc aaauauagaa      660

accguaauag aauuucaaca aaaaaacaau cgacuauuag aaaucacccg agaauuuuca      720

gucaaugcag gcguaacaac accaguauca accuacaugu uaaccaacuc cgaacuacua      780

ucccucauaa acgacaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguca gacaacaauc uuauucaaua augugcauca uaaaagaaga aguucuagcc      900

uacguaguuc aacuuccauu auacggcgua auugauacac caugcuggaa acuacacaca      960

uccccacuau guacaacaaa cacaaaagaa ggaucaaaca ucugcuuaac uagaacagac     1020

agaggauggu acugcgacaa cgcaggauca gucucauucu uuccacaagc agaaacaugc     1080

aagguccaau caaacagagu auucugcgac acaaugaacu ccuuaacacu accaucugaa     1140

guaaaccuau guaauguaga cauauuuaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uauccucauc aguaauuaca agccucggag ccauaguauc augcuacgga     1260

aaaacaaaau guacagcauc aaacaaaaac agaggaauaa uaaaaacguu cuccaacgga     1320

ugcgacuaug uaucaaacaa aggcguagac acaguaucag ucggaaauac ccuuuacugc     1380

guaaacaaac aagaaggcca aagucuauac guaaaaggag agccaauaau aaacuuuuau     1440

gacccccuug uauucccauc ugacgaauuu gaugcaucaa uaucccaagu caacgaaaaa     1500

aucaaccaau cauuagccuu uauuagaaaa agugacgaac uauuacacaa cguuaaugca     1560

gggaaaucaa caacaaauau aaugauuaca accauaauua uaguuaucau aguuauacua     1620

cucucacuaa ucgcaguagg auuacuauua uacugcaaag caagauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2109
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2109
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagccaac gcaaucacaa ccauacuuac agcuguuacc      180

uucugcuucg cauccggcca aaauaucacc gaagaguucu accaaucaac cugcuccgcc      240

gucagcaaag gauaccucgg cgcccuccga accggauggu acacuucugu caucacaauc      300

gaacucucca acaucaaaga aaacaaaugc aacgguaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaagua caaaaacgcc gucaccgaac ugcaacuccu caugcaaucc      420

acaccagcaa cgggaucagg auccgccauc ugcucaggcg ucgccgucug caaaguccug      480

caccuagaag gagaaguaaa caaaauuaaa uccgcccuac ucuccaccaa caaagcaguc      540

gucucacuau ccaacggcgu cuccguccuc accuuuaagg uccucgaccu caaaaauuau      600

auagacaaac aacuccuccc cauccuaaac aaacaaucau gcuccauccc caacauagaa      660

accgucaucg aauuucaaca gaaaaacaac cgacucuuag aaauuacccg cgaguucagc      720

gucaacgccg gagucaccac acccgucuca accuacaugc ucaccaacuc agaacuccuc      780

ucacuaauca augauaugcc caucacaaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gccaacaaag cuacuccauc auguguauca uuaaagaaga aguccucgcc      900

uacgucgucc aacuuccgcu cuacggcgua aucgacaccc ccugcuggaa acuucacacc      960

ucgccccucu gcaccacaaa caccaaagaa ggcuccaaca ucugccuaac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucucauuuu ucccccaggc ggagaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cucuuacccu cccaucagaa     1140

guaaaccucu gcaacgucga caucuuuaac cccaaauacg auugcaagau aaugaccucc     1200

aaaacagacg ucucaucguc cgucaucacc ucccuaggag cuaucgucuc cugcuacggc     1260

aagaccaaau gcaccgcuuc caacaaaaac cgcggcauca ucaaaaccuu cuccaacggg     1320

ugcgacuacg ucucuaacaa aggcguggac acaguauccg uaggaaacac acuguacugc     1380

guaaacaaac aagagggcca aucgcuuuac gucaaaggcg agccaauuau caacuucuac     1440

gacccgcucg ucuucccauc agacgaguuc gacgcaucca ucucccaagu caacgagaaa     1500

aucaaucagu cccucgccuu cauacgcaaa uccgacgaac uccuacauaa cguaaacgcc     1560

ggcaaaucua ccacaaacau caugaucaca accaucauca ucguaaucau cgucauccuu     1620

cucucgcuca ucgccguagg acugcuacuu uacugcaagg cccgcuaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2110
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2110
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2111
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2111
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2112
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2112
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2113
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2113
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2114
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2114
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2115
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2115
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2116
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2116
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau cuuaaaagca      120

aacgcaauaa caacuauucu aaccgcagua acauuuuguu ucgcaucagg acaaaacaua      180

accgaagaau uuuaccaauc aacauguucc gcaguuucaa aaggauacuu aggcgcacua      240

agaacaggcu gguacaccuc cgugauaaca auagaauuau caaacauaaa agaaaacaaa      300

uguaauggaa cugacgccaa aguaaaacua auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacug aacuacaauu acuaaugcaa uccaccccag caacaggcuc aggcucagca      420

auuugcuccg gagucgcugu cugcaaagua cuacaucuug aaggcgaagu caauaaaaua      480

aaaucagcac uucuaucaac aaacaaagca guagucucac uaucaaacgg aguaucagua      540

cuaacauuua aaguauuaga ucuaaaaaac uauauagaua aacaacuacu acccauacuc      600

aauaaacaau ccuguucaau accaaauaua gaaaccguaa uagaauuuca acaaaaaaac      660

aaucgacuau uagaaaucac ccgagaauuu ucagucaaug caggcguaac aacaccagua      720

ucaaccuaca uguuaaccaa cuccgaacua cuaucccuca uaaacgacau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag ucagacaaca aucuuauuca      840

auaaugugca ucauaaaaga agaaguucua gccuacguag uucaacuucc auuauacggc      900

guaauugaua caccaugcug gaaacuacac acauccccac uauguacaac aaacacaaaa      960

gaaggaucaa acaucugcuu aacuagaaca gacagaggau gguacugcga caacgcagga     1020

ucagucucau ucuuuccaca agcagaaaca ugcaaggucc aaucaaacag aguauucugc     1080

gacacaauga acuccuuaac acuaccaucu gaaguaaacc uauguaaugu agacauauuu     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguauccuc aucaguaauu     1200

acaagccucg gagccauagu aucaugcuac ggaaaaacaa aauguacagc aucaaacaaa     1260

aacagaggaa uaauaaaaac guucuccaac ggaugcgacu auguaucaaa caaaggcgua     1320

gacacaguau cagucggaaa uacccuuuac ugcguaaaca aacaagaagg ccaaagucua     1380

uacguaaaag gagagccaau aauaaacuuu uaugaccccc uuguauuccc aucugacgaa     1440

uuugaugcau caauauccca agucaacgaa aaaaucaacc aaucauuagc cuuuauuaga     1500

aaaagugacg aacuauuaca caacguuaau gcagggaaau caacaacaaa uauaaugauu     1560

acaaccauaa uuauaguuau cauaguuaua cuacucucac uaaucgcagu aggauuacua     1620

uuauacugca aagcaagaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2117
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2117
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagcc      120

aacgcaauca caaccauacu uacagcuguu accuucugcu ucgcauccgg ccaaaauauc      180

accgaagagu ucuaccaauc aaccugcucc gccgucagca aaggauaccu cggcgcccuc      240

cgaaccggau gguacacuuc ugucaucaca aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggua ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa guacaaaaac      360

gccgucaccg aacugcaacu ccucaugcaa uccacaccag caacgggauc aggauccgcc      420

aucugcucag gcgucgccgu cugcaaaguc cugcaccuag aaggagaagu aaacaaaauu      480

aaauccgccc uacucuccac caacaaagca gucgucucac uauccaacgg cgucuccguc      540

cucaccuuua agguccucga ccucaaaaau uauauagaca aacaacuccu ccccauccua      600

aacaaacaau caugcuccau ccccaacaua gaaaccguca ucgaauuuca acagaaaaac      660

aaccgacucu uagaaauuac ccgcgaguuc agcgucaacg ccggagucac cacacccguc      720

ucaaccuaca ugcucaccaa cucagaacuc cucucacuaa ucaaugauau gcccaucaca      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgccaaca aagcuacucc      840

aucaugugua ucauuaaaga agaaguccuc gccuacgucg uccaacuucc gcucuacggc      900

guaaucgaca cccccugcug gaaacuucac accucgcccc ucugcaccac aaacaccaaa      960

gaaggcucca acaucugccu aacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucucau uuuuccccca ggcggagacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucucuuac ccucccauca gaaguaaacc ucugcaacgu cgacaucuuu     1140

aaccccaaau acgauugcaa gauaaugacc uccaaaacag acgucucauc guccgucauc     1200

accucccuag gagcuaucgu cuccugcuac ggcaagacca aaugcaccgc uuccaacaaa     1260

aaccgcggca ucaucaaaac cuucuccaac gggugcgacu acgucucuaa caaaggcgug     1320

gacacaguau ccguaggaaa cacacuguac ugcguaaaca aacaagaggg ccaaucgcuu     1380

uacgucaaag gcgagccaau uaucaacuuc uacgacccgc ucgucuuccc aucagacgag     1440

uucgacgcau ccaucuccca agucaacgag aaaaucaauc agucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca uaacguaaac gccggcaaau cuaccacaaa caucaugauc     1560

acaaccauca ucaucguaau caucgucauc cuucucucgc ucaucgccgu aggacugcua     1620

cuuuacugca aggcccgcua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2118
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2118
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2119
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2119
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2120
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2120
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2121
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2121
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2122
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2122
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2123
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2123
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2124
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2124
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau cuuaaaagca      120

aacgcaauaa caacuauucu aaccgcagua acauuuuguu ucgcaucagg acaaaacaua      180

accgaagaau uuuaccaauc aacauguucc gcaguuucaa aaggauacuu aggcgcacua      240

agaacaggcu gguacaccuc cgugauaaca auagaauuau caaacauaaa agaaaacaaa      300

uguaauggaa cugacgccaa aguaaaacua auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacug aacuacaauu acuaaugcaa uccaccccag caacaggcuc aggcucagca      420

auuugcuccg gagucgcugu cugcaaagua cuacaucuug aaggcgaagu caauaaaaua      480

aaaucagcac uucuaucaac aaacaaagca guagucucac uaucaaacgg aguaucagua      540

cuaacauuua aaguauuaga ucuaaaaaac uauauagaua aacaacuacu acccauacuc      600

aauaaacaau ccuguucaau accaaauaua gaaaccguaa uagaauuuca acaaaaaaac      660

aaucgacuau uagaaaucac ccgagaauuu ucagucaaug caggcguaac aacaccagua      720

ucaaccuaca uguuaaccaa cuccgaacua cuaucccuca uaaacgacau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag ucagacaaca aucuuauuca      840

auaaugugca ucauaaaaga agaaguucua gccuacguag uucaacuucc auuauacggc      900

guaauugaua caccaugcug gaaacuacac acauccccac uauguacaac aaacacaaaa      960

gaaggaucaa acaucugcuu aacuagaaca gacagaggau gguacugcga caacgcagga     1020

ucagucucau ucuuuccaca agcagaaaca ugcaaggucc aaucaaacag aguauucugc     1080

gacacaauga acuccuuaac acuaccaucu gaaguaaacc uauguaaugu agacauauuu     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguauccuc aucaguaauu     1200

acaagccucg gagccauagu aucaugcuac ggaaaaacaa aauguacagc aucaaacaaa     1260

aacagaggaa uaauaaaaac guucuccaac ggaugcgacu auguaucaaa caaaggcgua     1320

gacacaguau cagucggaaa uacccuuuac ugcguaaaca aacaagaagg ccaaagucua     1380

uacguaaaag gagagccaau aauaaacuuu uaugaccccc uuguauuccc aucugacgaa     1440

uuugaugcau caauauccca agucaacgaa aaaaucaacc aaucauuagc cuuuauuaga     1500

aaaagugacg aacuauuaca caacguuaau gcagggaaau caacaacaaa uauaaugauu     1560

acaaccauaa uuauaguuau cauaguuaua cuacucucac uaaucgcagu aggauuacua     1620

uuauacugca aagcaagaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2125
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2125
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagcc      120

aacgcaauca caaccauacu uacagcuguu accuucugcu ucgcauccgg ccaaaauauc      180

accgaagagu ucuaccaauc aaccugcucc gccgucagca aaggauaccu cggcgcccuc      240

cgaaccggau gguacacuuc ugucaucaca aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggua ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa guacaaaaac      360

gccgucaccg aacugcaacu ccucaugcaa uccacaccag caacgggauc aggauccgcc      420

aucugcucag gcgucgccgu cugcaaaguc cugcaccuag aaggagaagu aaacaaaauu      480

aaauccgccc uacucuccac caacaaagca gucgucucac uauccaacgg cgucuccguc      540

cucaccuuua agguccucga ccucaaaaau uauauagaca aacaacuccu ccccauccua      600

aacaaacaau caugcuccau ccccaacaua gaaaccguca ucgaauuuca acagaaaaac      660

aaccgacucu uagaaauuac ccgcgaguuc agcgucaacg ccggagucac cacacccguc      720

ucaaccuaca ugcucaccaa cucagaacuc cucucacuaa ucaaugauau gcccaucaca      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgccaaca aagcuacucc      840

aucaugugua ucauuaaaga agaaguccuc gccuacgucg uccaacuucc gcucuacggc      900

guaaucgaca cccccugcug gaaacuucac accucgcccc ucugcaccac aaacaccaaa      960

gaaggcucca acaucugccu aacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucucau uuuuccccca ggcggagacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucucuuac ccucccauca gaaguaaacc ucugcaacgu cgacaucuuu     1140

aaccccaaau acgauugcaa gauaaugacc uccaaaacag acgucucauc guccgucauc     1200

accucccuag gagcuaucgu cuccugcuac ggcaagacca aaugcaccgc uuccaacaaa     1260

aaccgcggca ucaucaaaac cuucuccaac gggugcgacu acgucucuaa caaaggcgug     1320

gacacaguau ccguaggaaa cacacuguac ugcguaaaca aacaagaggg ccaaucgcuu     1380

uacgucaaag gcgagccaau uaucaacuuc uacgacccgc ucgucuuccc aucagacgag     1440

uucgacgcau ccaucuccca agucaacgag aaaaucaauc agucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca uaacguaaac gccggcaaau cuaccacaaa caucaugauc     1560

acaaccauca ucaucguaau caucgucauc cuucucucgc ucaucgccgu aggacugcua     1620

cuuuacugca aggcccgcua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2126
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2126
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2127
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2127
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2128
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2128
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2129
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2129
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2130
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2130
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2131
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2131
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2132
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2132
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucaucuuaaa agcaaacgca      120

auaacaacua uucuaaccgc aguaacauuu uguuucgcau caggacaaaa cauaaccgaa      180

gaauuuuacc aaucaacaug uuccgcaguu ucaaaaggau acuuaggcgc acuaagaaca      240

ggcugguaca ccuccgugau aacaauagaa uuaucaaaca uaaaagaaaa caaauguaau      300

ggaacugacg ccaaaguaaa acuaauaaaa caagaacuag acaaauauaa aaacgcagua      360

acugaacuac aauuacuaau gcaauccacc ccagcaacag gcucaggcuc agcaauuugc      420

uccggagucg cugucugcaa aguacuacau cuugaaggcg aagucaauaa aauaaaauca      480

gcacuucuau caacaaacaa agcaguaguc ucacuaucaa acggaguauc aguacuaaca      540

uuuaaaguau uagaucuaaa aaacuauaua gauaaacaac uacuacccau acucaauaaa      600

caauccuguu caauaccaaa uauagaaacc guaauagaau uucaacaaaa aaacaaucga      660

cuauuagaaa ucacccgaga auuuucaguc aaugcaggcg uaacaacacc aguaucaacc      720

uacauguuaa ccaacuccga acuacuaucc cucauaaacg acaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auagucagac aacaaucuua uucaauaaug      840

ugcaucauaa aagaagaagu ucuagccuac guaguucaac uuccauuaua cggcguaauu      900

gauacaccau gcuggaaacu acacacaucc ccacuaugua caacaaacac aaaagaagga      960

ucaaacaucu gcuuaacuag aacagacaga ggaugguacu gcgacaacgc aggaucaguc     1020

ucauucuuuc cacaagcaga aacaugcaag guccaaucaa acagaguauu cugcgacaca     1080

augaacuccu uaacacuacc aucugaagua aaccuaugua auguagacau auuuaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguau ccucaucagu aauuacaagc     1200

cucggagcca uaguaucaug cuacggaaaa acaaaaugua cagcaucaaa caaaaacaga     1260

ggaauaauaa aaacguucuc caacggaugc gacuauguau caaacaaagg cguagacaca     1320

guaucagucg gaaauacccu uuacugcgua aacaaacaag aaggccaaag ucuauacgua     1380

aaaggagagc caauaauaaa cuuuuaugac ccccuuguau ucccaucuga cgaauuugau     1440

gcaucaauau cccaagucaa cgaaaaaauc aaccaaucau uagccuuuau uagaaaaagu     1500

gacgaacuau uacacaacgu uaaugcaggg aaaucaacaa caaauauaau gauuacaacc     1560

auaauuauag uuaucauagu uauacuacuc ucacuaaucg caguaggauu acuauuauac     1620

ugcaaagcaa gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2133
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2133
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agccaacgca      120

aucacaacca uacuuacagc uguuaccuuc ugcuucgcau ccggccaaaa uaucaccgaa      180

gaguucuacc aaucaaccug cuccgccguc agcaaaggau accucggcgc ccuccgaacc      240

ggaugguaca cuucugucau cacaaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

gguaccgacg cgaaagucaa acucaucaaa caagaacuag acaaguacaa aaacgccguc      360

accgaacugc aacuccucau gcaauccaca ccagcaacgg gaucaggauc cgccaucugc      420

ucaggcgucg ccgucugcaa aguccugcac cuagaaggag aaguaaacaa aauuaaaucc      480

gcccuacucu ccaccaacaa agcagucguc ucacuaucca acggcgucuc cguccucacc      540

uuuaaggucc ucgaccucaa aaauuauaua gacaaacaac uccuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa cauagaaacc gucaucgaau uucaacagaa aaacaaccga      660

cucuuagaaa uuacccgcga guucagcguc aacgccggag ucaccacacc cgucucaacc      720

uacaugcuca ccaacucaga acuccucuca cuaaucaaug auaugcccau cacaaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucgcc aacaaagcua cuccaucaug      840

uguaucauua aagaagaagu ccucgccuac gucguccaac uuccgcucua cggcguaauc      900

gacacccccu gcuggaaacu ucacaccucg ccccucugca ccacaaacac caaagaaggc      960

uccaacaucu gccuaacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

ucauuuuucc cccaggcgga gaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucuc uuacccuccc aucagaagua aaccucugca acgucgacau cuuuaacccc     1140

aaauacgauu gcaagauaau gaccuccaaa acagacgucu caucguccgu caucaccucc     1200

cuaggagcua ucgucuccug cuacggcaag accaaaugca ccgcuuccaa caaaaaccgc     1260

ggcaucauca aaaccuucuc caacgggugc gacuacgucu cuaacaaagg cguggacaca     1320

guauccguag gaaacacacu guacugcgua aacaaacaag agggccaauc gcuuuacguc     1380

aaaggcgagc caauuaucaa cuucuacgac ccgcucgucu ucccaucaga cgaguucgac     1440

gcauccaucu cccaagucaa cgagaaaauc aaucaguccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacauaacgu aaacgccggc aaaucuacca caaacaucau gaucacaacc     1560

aucaucaucg uaaucaucgu cauccuucuc ucgcucaucg ccguaggacu gcuacuuuac     1620

ugcaaggccc gcuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2134
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2134
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2135
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2135
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2136
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2136
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2137
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2137
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2138
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2138
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2139
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2139
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2140
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2140
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu caucuuaaaa      120

gcaaacgcaa uaacaacuau ucuaaccgca guaacauuuu guuucgcauc aggacaaaac      180

auaaccgaag aauuuuacca aucaacaugu uccgcaguuu caaaaggaua cuuaggcgca      240

cuaagaacag gcugguacac cuccgugaua acaauagaau uaucaaacau aaaagaaaac      300

aaauguaaug gaacugacgc caaaguaaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cugaacuaca auuacuaaug caauccaccc cagcaacagg cucaggcuca      420

gcaauuugcu ccggagucgc ugucugcaaa guacuacauc uugaaggcga agucaauaaa      480

auaaaaucag cacuucuauc aacaaacaaa gcaguagucu cacuaucaaa cggaguauca      540

guacuaacau uuaaaguauu agaucuaaaa aacuauauag auaaacaacu acuacccaua      600

cucaauaaac aauccuguuc aauaccaaau auagaaaccg uaauagaauu ucaacaaaaa      660

aacaaucgac uauuagaaau cacccgagaa uuuucaguca augcaggcgu aacaacacca      720

guaucaaccu acauguuaac caacuccgaa cuacuauccc ucauaaacga caugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uagucagaca acaaucuuau      840

ucaauaaugu gcaucauaaa agaagaaguu cuagccuacg uaguucaacu uccauuauac      900

ggcguaauug auacaccaug cuggaaacua cacacauccc cacuauguac aacaaacaca      960

aaagaaggau caaacaucug cuuaacuaga acagacagag gaugguacug cgacaacgca     1020

ggaucagucu cauucuuucc acaagcagaa acaugcaagg uccaaucaaa cagaguauuc     1080

ugcgacacaa ugaacuccuu aacacuacca ucugaaguaa accuauguaa uguagacaua     1140

uuuaacccaa aauacgacug caaaauaaug accucaaaaa cagacguauc cucaucagua     1200

auuacaagcc ucggagccau aguaucaugc uacggaaaaa caaaauguac agcaucaaac     1260

aaaaacagag gaauaauaaa aacguucucc aacggaugcg acuauguauc aaacaaaggc     1320

guagacacag uaucagucgg aaauacccuu uacugcguaa acaaacaaga aggccaaagu     1380

cuauacguaa aaggagagcc aauaauaaac uuuuaugacc cccuuguauu cccaucugac     1440

gaauuugaug caucaauauc ccaagucaac gaaaaaauca accaaucauu agccuuuauu     1500

agaaaaagug acgaacuauu acacaacguu aaugcaggga aaucaacaac aaauauaaug     1560

auuacaacca uaauuauagu uaucauaguu auacuacucu cacuaaucgc aguaggauua     1620

cuauuauacu gcaaagcaag auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2141
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2141
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gccaacgcaa ucacaaccau acuuacagcu guuaccuucu gcuucgcauc cggccaaaau      180

aucaccgaag aguucuacca aucaaccugc uccgccguca gcaaaggaua ccucggcgcc      240

cuccgaaccg gaugguacac uucugucauc acaaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg guaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaguacaaa      360

aacgccguca ccgaacugca acuccucaug caauccacac cagcaacggg aucaggaucc      420

gccaucugcu caggcgucgc cgucugcaaa guccugcacc uagaaggaga aguaaacaaa      480

auuaaauccg cccuacucuc caccaacaaa gcagucgucu cacuauccaa cggcgucucc      540

guccucaccu uuaagguccu cgaccucaaa aauuauauag acaaacaacu ccuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac auagaaaccg ucaucgaauu ucaacagaaa      660

aacaaccgac ucuuagaaau uacccgcgag uucagcguca acgccggagu caccacaccc      720

gucucaaccu acaugcucac caacucagaa cuccucucac uaaucaauga uaugcccauc      780

acaaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucgcca acaaagcuac      840

uccaucaugu guaucauuaa agaagaaguc cucgccuacg ucguccaacu uccgcucuac      900

ggcguaaucg acacccccug cuggaaacuu cacaccucgc cccucugcac cacaaacacc      960

aaagaaggcu ccaacaucug ccuaacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu cauuuuuccc ccaggcggag accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucucu uacccuccca ucagaaguaa accucugcaa cgucgacauc     1140

uuuaacccca aauacgauug caagauaaug accuccaaaa cagacgucuc aucguccguc     1200

aucaccuccc uaggagcuau cgucuccugc uacggcaaga ccaaaugcac cgcuuccaac     1260

aaaaaccgcg gcaucaucaa aaccuucucc aacgggugcg acuacgucuc uaacaaaggc     1320

guggacacag uauccguagg aaacacacug uacugcguaa acaaacaaga gggccaaucg     1380

cuuuacguca aaggcgagcc aauuaucaac uucuacgacc cgcucgucuu cccaucagac     1440

gaguucgacg cauccaucuc ccaagucaac gagaaaauca aucagucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acauaacgua aacgccggca aaucuaccac aaacaucaug     1560

aucacaacca ucaucaucgu aaucaucguc auccuucucu cgcucaucgc cguaggacug     1620

cuacuuuacu gcaaggcccg cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2142
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2142
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2143
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2143
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2144
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2144
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2145
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2145
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2146
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2146
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2147
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2147
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2148
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2148
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucaucuuaaa agcaaacgca      120

auaacaacua uucuaaccgc aguaacauuu uguuucgcau caggacaaaa cauaaccgaa      180

gaauuuuacc aaucaacaug uuccgcaguu ucaaaaggau acuuaggcgc acuaagaaca      240

ggcugguaca ccuccgugau aacaauagaa uuaucaaaca uaaaagaaaa caaauguaau      300

ggaacugacg ccaaaguaaa acuaauaaaa caagaacuag acaaauauaa aaacgcagua      360

acugaacuac aauuacuaau gcaauccacc ccagcaacag gcucaggcuc agcaauuugc      420

uccggagucg cugucugcaa aguacuacau cuugaaggcg aagucaauaa aauaaaauca      480

gcacuucuau caacaaacaa agcaguaguc ucacuaucaa acggaguauc aguacuaaca      540

uuuaaaguau uagaucuaaa aaacuauaua gauaaacaac uacuacccau acucaauaaa      600

caauccuguu caauaccaaa uauagaaacc guaauagaau uucaacaaaa aaacaaucga      660

cuauuagaaa ucacccgaga auuuucaguc aaugcaggcg uaacaacacc aguaucaacc      720

uacauguuaa ccaacuccga acuacuaucc cucauaaacg acaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auagucagac aacaaucuua uucaauaaug      840

ugcaucauaa aagaagaagu ucuagccuac guaguucaac uuccauuaua cggcguaauu      900

gauacaccau gcuggaaacu acacacaucc ccacuaugua caacaaacac aaaagaagga      960

ucaaacaucu gcuuaacuag aacagacaga ggaugguacu gcgacaacgc aggaucaguc     1020

ucauucuuuc cacaagcaga aacaugcaag guccaaucaa acagaguauu cugcgacaca     1080

augaacuccu uaacacuacc aucugaagua aaccuaugua auguagacau auuuaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguau ccucaucagu aauuacaagc     1200

cucggagcca uaguaucaug cuacggaaaa acaaaaugua cagcaucaaa caaaaacaga     1260

ggaauaauaa aaacguucuc caacggaugc gacuauguau caaacaaagg cguagacaca     1320

guaucagucg gaaauacccu uuacugcgua aacaaacaag aaggccaaag ucuauacgua     1380

aaaggagagc caauaauaaa cuuuuaugac ccccuuguau ucccaucuga cgaauuugau     1440

gcaucaauau cccaagucaa cgaaaaaauc aaccaaucau uagccuuuau uagaaaaagu     1500

gacgaacuau uacacaacgu uaaugcaggg aaaucaacaa caaauauaau gauuacaacc     1560

auaauuauag uuaucauagu uauacuacuc ucacuaaucg caguaggauu acuauuauac     1620

ugcaaagcaa gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2149
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2149
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agccaacgca      120

aucacaacca uacuuacagc uguuaccuuc ugcuucgcau ccggccaaaa uaucaccgaa      180

gaguucuacc aaucaaccug cuccgccguc agcaaaggau accucggcgc ccuccgaacc      240

ggaugguaca cuucugucau cacaaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

gguaccgacg cgaaagucaa acucaucaaa caagaacuag acaaguacaa aaacgccguc      360

accgaacugc aacuccucau gcaauccaca ccagcaacgg gaucaggauc cgccaucugc      420

ucaggcgucg ccgucugcaa aguccugcac cuagaaggag aaguaaacaa aauuaaaucc      480

gcccuacucu ccaccaacaa agcagucguc ucacuaucca acggcgucuc cguccucacc      540

uuuaaggucc ucgaccucaa aaauuauaua gacaaacaac uccuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa cauagaaacc gucaucgaau uucaacagaa aaacaaccga      660

cucuuagaaa uuacccgcga guucagcguc aacgccggag ucaccacacc cgucucaacc      720

uacaugcuca ccaacucaga acuccucuca cuaaucaaug auaugcccau cacaaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucgcc aacaaagcua cuccaucaug      840

uguaucauua aagaagaagu ccucgccuac gucguccaac uuccgcucua cggcguaauc      900

gacacccccu gcuggaaacu ucacaccucg ccccucugca ccacaaacac caaagaaggc      960

uccaacaucu gccuaacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

ucauuuuucc cccaggcgga gaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucuc uuacccuccc aucagaagua aaccucugca acgucgacau cuuuaacccc     1140

aaauacgauu gcaagauaau gaccuccaaa acagacgucu caucguccgu caucaccucc     1200

cuaggagcua ucgucuccug cuacggcaag accaaaugca ccgcuuccaa caaaaaccgc     1260

ggcaucauca aaaccuucuc caacgggugc gacuacgucu cuaacaaagg cguggacaca     1320

guauccguag gaaacacacu guacugcgua aacaaacaag agggccaauc gcuuuacguc     1380

aaaggcgagc caauuaucaa cuucuacgac ccgcucgucu ucccaucaga cgaguucgac     1440

gcauccaucu cccaagucaa cgagaaaauc aaucaguccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacauaacgu aaacgccggc aaaucuacca caaacaucau gaucacaacc     1560

aucaucaucg uaaucaucgu cauccuucuc ucgcucaucg ccguaggacu gcuacuuuac     1620

ugcaaggccc gcuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2150
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2150
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2151
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2151
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2152
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2152
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2153
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2153
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2154
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2154
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2155
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2155
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2156
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2156
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucu uaaaagcaaa cgcaauaaca acuauucuaa ccgcaguaac auuuuguuuc      240

gcaucaggac aaaacauaac cgaagaauuu uaccaaucaa cauguuccgc aguuucaaaa      300

ggauacuuag gcgcacuaag aacaggcugg uacaccuccg ugauaacaau agaauuauca      360

aacauaaaag aaaacaaaug uaauggaacu gacgccaaag uaaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacugaa cuacaauuac uaaugcaauc caccccagca      480

acaggcucag gcucagcaau uugcuccgga gucgcugucu gcaaaguacu acaucuugaa      540

ggcgaaguca auaaaauaaa aucagcacuu cuaucaacaa acaaagcagu agucucacua      600

ucaaacggag uaucaguacu aacauuuaaa guauuagauc uaaaaaacua uauagauaaa      660

caacuacuac ccauacucaa uaaacaaucc uguucaauac caaauauaga aaccguaaua      720

gaauuucaac aaaaaaacaa ucgacuauua gaaaucaccc gagaauuuuc agucaaugca      780

ggcguaacaa caccaguauc aaccuacaug uuaaccaacu ccgaacuacu aucccucaua      840

aacgacaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauaguc      900

agacaacaau cuuauucaau aaugugcauc auaaaagaag aaguucuagc cuacguaguu      960

caacuuccau uauacggcgu aauugauaca ccaugcugga aacuacacac auccccacua     1020

uguacaacaa acacaaaaga aggaucaaac aucugcuuaa cuagaacaga cagaggaugg     1080

uacugcgaca acgcaggauc agucucauuc uuuccacaag cagaaacaug caagguccaa     1140

ucaaacagag uauucugcga cacaaugaac uccuuaacac uaccaucuga aguaaaccua     1200

uguaauguag acauauuuaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guauccucau caguaauuac aagccucgga gccauaguau caugcuacgg aaaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaaua auaaaaacgu ucuccaacgg augcgacuau     1380

guaucaaaca aaggcguaga cacaguauca gucggaaaua cccuuuacug cguaaacaaa     1440

caagaaggcc aaagucuaua cguaaaagga gagccaauaa uaaacuuuua ugacccccuu     1500

guauucccau cugacgaauu ugaugcauca auaucccaag ucaacgaaaa aaucaaccaa     1560

ucauuagccu uuauuagaaa aagugacgaa cuauuacaca acguuaaugc agggaaauca     1620

acaacaaaua uaaugauuac aaccauaauu auaguuauca uaguuauacu acucucacua     1680

aucgcaguag gauuacuauu auacugcaaa gcaagauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2157
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2157
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagccaa cgcaaucaca accauacuua cagcuguuac cuucugcuuc      240

gcauccggcc aaaauaucac cgaagaguuc uaccaaucaa ccugcuccgc cgucagcaaa      300

ggauaccucg gcgcccuccg aaccggaugg uacacuucug ucaucacaau cgaacucucc      360

aacaucaaag aaaacaaaug caacgguacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaagu acaaaaacgc cgucaccgaa cugcaacucc ucaugcaauc cacaccagca      480

acgggaucag gauccgccau cugcucaggc gucgccgucu gcaaaguccu gcaccuagaa      540

ggagaaguaa acaaaauuaa auccgcccua cucuccacca acaaagcagu cgucucacua      600

uccaacggcg ucuccguccu caccuuuaag guccucgacc ucaaaaauua uauagacaaa      660

caacuccucc ccauccuaaa caaacaauca ugcuccaucc ccaacauaga aaccgucauc      720

gaauuucaac agaaaaacaa ccgacucuua gaaauuaccc gcgaguucag cgucaacgcc      780

ggagucacca cacccgucuc aaccuacaug cucaccaacu cagaacuccu cucacuaauc      840

aaugauaugc ccaucacaaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgccaacaaa gcuacuccau cauguguauc auuaaagaag aaguccucgc cuacgucguc      960

caacuuccgc ucuacggcgu aaucgacacc cccugcugga aacuucacac cucgccccuc     1020

ugcaccacaa acaccaaaga aggcuccaac aucugccuaa cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucucauuu uucccccagg cggagaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucucuuaccc ucccaucaga aguaaaccuc     1200

ugcaacgucg acaucuuuaa ccccaaauac gauugcaaga uaaugaccuc caaaacagac     1260

gucucaucgu ccgucaucac cucccuagga gcuaucgucu ccugcuacgg caagaccaaa     1320

ugcaccgcuu ccaacaaaaa ccgcggcauc aucaaaaccu ucuccaacgg gugcgacuac     1380

gucucuaaca aaggcgugga cacaguaucc guaggaaaca cacuguacug cguaaacaaa     1440

caagagggcc aaucgcuuua cgucaaaggc gagccaauua ucaacuucua cgacccgcuc     1500

gucuucccau cagacgaguu cgacgcaucc aucucccaag ucaacgagaa aaucaaucag     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaua acguaaacgc cggcaaaucu     1620

accacaaaca ucaugaucac aaccaucauc aucguaauca ucgucauccu ucucucgcuc     1680

aucgccguag gacugcuacu uuacugcaag gcccgcuaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2158
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2158
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2159
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2159
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2160
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2160
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2161
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2161
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2162
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2162
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2163
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2163
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2164
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2164
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc      120

uaaccgcagu aacauuuugu uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau      180

caacauguuc cgcaguuuca aaaggauacu uaggcgcacu aagaacaggc ugguacaccu      240

ccgugauaac aauagaauua ucaaacauaa aagaaaacaa auguaaugga acugacgcca      300

aaguaaaacu aauaaaacaa gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau      360

uacuaaugca auccacccca gcaacaggcu caggcucagc aauuugcucc ggagucgcug      420

ucugcaaagu acuacaucuu gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa      480

caaacaaagc aguagucuca cuaucaaacg gaguaucagu acuaacauuu aaaguauuag      540

aucuaaaaaa cuauauagau aaacaacuac uacccauacu caauaaacaa uccuguucaa      600

uaccaaauau agaaaccgua auagaauuuc aacaaaaaaa caaucgacua uuagaaauca      660

cccgagaauu uucagucaau gcaggcguaa caacaccagu aucaaccuac auguuaacca      720

acuccgaacu acuaucccuc auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua gucagacaac aaucuuauuc aauaaugugc aucauaaaag      840

aagaaguucu agccuacgua guucaacuuc cauuauacgg cguaauugau acaccaugcu      900

ggaaacuaca cacaucccca cuauguacaa caaacacaaa agaaggauca aacaucugcu      960

uaacuagaac agacagagga ugguacugcg acaacgcagg aucagucuca uucuuuccac     1020

aagcagaaac augcaagguc caaucaaaca gaguauucug cgacacaaug aacuccuuaa     1080

cacuaccauc ugaaguaaac cuauguaaug uagacauauu uaacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguauccu caucaguaau uacaagccuc ggagccauag     1200

uaucaugcua cggaaaaaca aaauguacag caucaaacaa aaacagagga auaauaaaaa     1260

cguucuccaa cggaugcgac uauguaucaa acaaaggcgu agacacagua ucagucggaa     1320

auacccuuua cugcguaaac aaacaagaag gccaaagucu auacguaaaa ggagagccaa     1380

uaauaaacuu uuaugacccc cuuguauucc caucugacga auuugaugca ucaauauccc     1440

aagucaacga aaaaaucaac caaucauuag ccuuuauuag aaaaagugac gaacuauuac     1500

acaacguuaa ugcagggaaa ucaacaacaa auauaaugau uacaaccaua auuauaguua     1560

ucauaguuau acuacucuca cuaaucgcag uaggauuacu auuauacugc aaagcaagau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2165
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2165
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc caacgcaauc acaaccauac      120

uuacagcugu uaccuucugc uucgcauccg gccaaaauau caccgaagag uucuaccaau      180

caaccugcuc cgccgucagc aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu      240

cugucaucac aaucgaacuc uccaacauca aagaaaacaa augcaacggu accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aguacaaaaa cgccgucacc gaacugcaac      360

uccucaugca auccacacca gcaacgggau caggauccgc caucugcuca ggcgucgccg      420

ucugcaaagu ccugcaccua gaaggagaag uaaacaaaau uaaauccgcc cuacucucca      480

ccaacaaagc agucgucuca cuauccaacg gcgucuccgu ccucaccuuu aagguccucg      540

accucaaaaa uuauauagac aaacaacucc uccccauccu aaacaaacaa ucaugcucca      600

uccccaacau agaaaccguc aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua      660

cccgcgaguu cagcgucaac gccggaguca ccacacccgu cucaaccuac augcucacca      720

acucagaacu ccucucacua aucaaugaua ugcccaucac aaacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgccaac aaagcuacuc caucaugugu aucauuaaag      840

aagaaguccu cgccuacguc guccaacuuc cgcucuacgg cguaaucgac acccccugcu      900

ggaaacuuca caccucgccc cucugcacca caaacaccaa agaaggcucc aacaucugcc      960

uaacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucuca uuuuuccccc     1020

aggcggagac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucucuua     1080

cccucccauc agaaguaaac cucugcaacg ucgacaucuu uaaccccaaa uacgauugca     1140

agauaaugac cuccaaaaca gacgucucau cguccgucau caccucccua ggagcuaucg     1200

ucuccugcua cggcaagacc aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa     1260

ccuucuccaa cgggugcgac uacgucucua acaaaggcgu ggacacagua uccguaggaa     1320

acacacugua cugcguaaac aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa     1380

uuaucaacuu cuacgacccg cucgucuucc caucagacga guucgacgca uccaucuccc     1440

aagucaacga gaaaaucaau cagucccucg ccuucauacg caaauccgac gaacuccuac     1500

auaacguaaa cgccggcaaa ucuaccacaa acaucaugau cacaaccauc aucaucguaa     1560

ucaucgucau ccuucucucg cucaucgccg uaggacugcu acuuuacugc aaggcccgcu     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2166
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2166
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2167
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2167
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2168
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2168
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2169
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2169
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2170
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2170
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2171
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2171
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2172
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2172
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucu uaaaagcaaa cgcaauaaca acuauucuaa ccgcaguaac auuuuguuuc      240

gcaucaggac aaaacauaac cgaagaauuu uaccaaucaa cauguuccgc aguuucaaaa      300

ggauacuuag gcgcacuaag aacaggcugg uacaccuccg ugauaacaau agaauuauca      360

aacauaaaag aaaacaaaug uaauggaacu gacgccaaag uaaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacugaa cuacaauuac uaaugcaauc caccccagca      480

acaggcucag gcucagcaau uugcuccgga gucgcugucu gcaaaguacu acaucuugaa      540

ggcgaaguca auaaaauaaa aucagcacuu cuaucaacaa acaaagcagu agucucacua      600

ucaaacggag uaucaguacu aacauuuaaa guauuagauc uaaaaaacua uauagauaaa      660

caacuacuac ccauacucaa uaaacaaucc uguucaauac caaauauaga aaccguaaua      720

gaauuucaac aaaaaaacaa ucgacuauua gaaaucaccc gagaauuuuc agucaaugca      780

ggcguaacaa caccaguauc aaccuacaug uuaaccaacu ccgaacuacu aucccucaua      840

aacgacaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauaguc      900

agacaacaau cuuauucaau aaugugcauc auaaaagaag aaguucuagc cuacguaguu      960

caacuuccau uauacggcgu aauugauaca ccaugcugga aacuacacac auccccacua     1020

uguacaacaa acacaaaaga aggaucaaac aucugcuuaa cuagaacaga cagaggaugg     1080

uacugcgaca acgcaggauc agucucauuc uuuccacaag cagaaacaug caagguccaa     1140

ucaaacagag uauucugcga cacaaugaac uccuuaacac uaccaucuga aguaaaccua     1200

uguaauguag acauauuuaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guauccucau caguaauuac aagccucgga gccauaguau caugcuacgg aaaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaaua auaaaaacgu ucuccaacgg augcgacuau     1380

guaucaaaca aaggcguaga cacaguauca gucggaaaua cccuuuacug cguaaacaaa     1440

caagaaggcc aaagucuaua cguaaaagga gagccaauaa uaaacuuuua ugacccccuu     1500

guauucccau cugacgaauu ugaugcauca auaucccaag ucaacgaaaa aaucaaccaa     1560

ucauuagccu uuauuagaaa aagugacgaa cuauuacaca acguuaaugc agggaaauca     1620

acaacaaaua uaaugauuac aaccauaauu auaguuauca uaguuauacu acucucacua     1680

aucgcaguag gauuacuauu auacugcaaa gcaagauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2173
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2173
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagccaa cgcaaucaca accauacuua cagcuguuac cuucugcuuc      240

gcauccggcc aaaauaucac cgaagaguuc uaccaaucaa ccugcuccgc cgucagcaaa      300

ggauaccucg gcgcccuccg aaccggaugg uacacuucug ucaucacaau cgaacucucc      360

aacaucaaag aaaacaaaug caacgguacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaagu acaaaaacgc cgucaccgaa cugcaacucc ucaugcaauc cacaccagca      480

acgggaucag gauccgccau cugcucaggc gucgccgucu gcaaaguccu gcaccuagaa      540

ggagaaguaa acaaaauuaa auccgcccua cucuccacca acaaagcagu cgucucacua      600

uccaacggcg ucuccguccu caccuuuaag guccucgacc ucaaaaauua uauagacaaa      660

caacuccucc ccauccuaaa caaacaauca ugcuccaucc ccaacauaga aaccgucauc      720

gaauuucaac agaaaaacaa ccgacucuua gaaauuaccc gcgaguucag cgucaacgcc      780

ggagucacca cacccgucuc aaccuacaug cucaccaacu cagaacuccu cucacuaauc      840

aaugauaugc ccaucacaaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgccaacaaa gcuacuccau cauguguauc auuaaagaag aaguccucgc cuacgucguc      960

caacuuccgc ucuacggcgu aaucgacacc cccugcugga aacuucacac cucgccccuc     1020

ugcaccacaa acaccaaaga aggcuccaac aucugccuaa cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucucauuu uucccccagg cggagaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucucuuaccc ucccaucaga aguaaaccuc     1200

ugcaacgucg acaucuuuaa ccccaaauac gauugcaaga uaaugaccuc caaaacagac     1260

gucucaucgu ccgucaucac cucccuagga gcuaucgucu ccugcuacgg caagaccaaa     1320

ugcaccgcuu ccaacaaaaa ccgcggcauc aucaaaaccu ucuccaacgg gugcgacuac     1380

gucucuaaca aaggcgugga cacaguaucc guaggaaaca cacuguacug cguaaacaaa     1440

caagagggcc aaucgcuuua cgucaaaggc gagccaauua ucaacuucua cgacccgcuc     1500

gucuucccau cagacgaguu cgacgcaucc aucucccaag ucaacgagaa aaucaaucag     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaua acguaaacgc cggcaaaucu     1620

accacaaaca ucaugaucac aaccaucauc aucguaauca ucgucauccu ucucucgcuc     1680

aucgccguag gacugcuacu uuacugcaag gcccgcuaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2174
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2174
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2175
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2175
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      540

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1380

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2176
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2176
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2177
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2177
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      480

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      540

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      600

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      720

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      780

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      840

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua      900

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc      960

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg     1020

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1080

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1140

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1200

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1260

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1320

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1380

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1440

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1500

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1560

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1620

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2178
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2178
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2179
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2179
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      480

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      540

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      600

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      720

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      780

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      840

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      900

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc      960

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc     1020

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1080

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1140

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1200

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1260

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1320

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1380

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1440

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1500

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1620

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2180
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2180
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc uaaccgcagu aacauuuugu      180

uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau caacauguuc cgcaguuuca      240

aaaggauacu uaggcgcacu aagaacaggc ugguacaccu ccgugauaac aauagaauua      300

ucaaacauaa aagaaaacaa auguaaugga acugacgcca aaguaaaacu aauaaaacaa      360

gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau uacuaaugca auccacccca      420

gcaacaggcu caggcucagc aauuugcucc ggagucgcug ucugcaaagu acuacaucuu      480

gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa caaacaaagc aguagucuca      540

cuaucaaacg gaguaucagu acuaacauuu aaaguauuag aucuaaaaaa cuauauagau      600

aaacaacuac uacccauacu caauaaacaa uccuguucaa uaccaaauau agaaaccgua      660

auagaauuuc aacaaaaaaa caaucgacua uuagaaauca cccgagaauu uucagucaau      720

gcaggcguaa caacaccagu aucaaccuac auguuaacca acuccgaacu acuaucccuc      780

auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      840

gucagacaac aaucuuauuc aauaaugugc aucauaaaag aagaaguucu agccuacgua      900

guucaacuuc cauuauacgg cguaauugau acaccaugcu ggaaacuaca cacaucccca      960

cuauguacaa caaacacaaa agaaggauca aacaucugcu uaacuagaac agacagagga     1020

ugguacugcg acaacgcagg aucagucuca uucuuuccac aagcagaaac augcaagguc     1080

caaucaaaca gaguauucug cgacacaaug aacuccuuaa cacuaccauc ugaaguaaac     1140

cuauguaaug uagacauauu uaacccaaaa uacgacugca aaauaaugac cucaaaaaca     1200

gacguauccu caucaguaau uacaagccuc ggagccauag uaucaugcua cggaaaaaca     1260

aaauguacag caucaaacaa aaacagagga auaauaaaaa cguucuccaa cggaugcgac     1320

uauguaucaa acaaaggcgu agacacagua ucagucggaa auacccuuua cugcguaaac     1380

aaacaagaag gccaaagucu auacguaaaa ggagagccaa uaauaaacuu uuaugacccc     1440

cuuguauucc caucugacga auuugaugca ucaauauccc aagucaacga aaaaaucaac     1500

caaucauuag ccuuuauuag aaaaagugac gaacuauuac acaacguuaa ugcagggaaa     1560

ucaacaacaa auauaaugau uacaaccaua auuauaguua ucauaguuau acuacucuca     1620

cuaaucgcag uaggauuacu auuauacugc aaagcaagau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2181
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2181
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuca uccuaaaagc caacgcaauc acaaccauac uuacagcugu uaccuucugc      180

uucgcauccg gccaaaauau caccgaagag uucuaccaau caaccugcuc cgccgucagc      240

aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu cugucaucac aaucgaacuc      300

uccaacauca aagaaaacaa augcaacggu accgacgcga aagucaaacu caucaaacaa      360

gaacuagaca aguacaaaaa cgccgucacc gaacugcaac uccucaugca auccacacca      420

gcaacgggau caggauccgc caucugcuca ggcgucgccg ucugcaaagu ccugcaccua      480

gaaggagaag uaaacaaaau uaaauccgcc cuacucucca ccaacaaagc agucgucuca      540

cuauccaacg gcgucuccgu ccucaccuuu aagguccucg accucaaaaa uuauauagac      600

aaacaacucc uccccauccu aaacaaacaa ucaugcucca uccccaacau agaaaccguc      660

aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua cccgcgaguu cagcgucaac      720

gccggaguca ccacacccgu cucaaccuac augcucacca acucagaacu ccucucacua      780

aucaaugaua ugcccaucac aaacgaccaa aagaaacuca uguccaacaa cguacaaauc      840

guucgccaac aaagcuacuc caucaugugu aucauuaaag aagaaguccu cgccuacguc      900

guccaacuuc cgcucuacgg cguaaucgac acccccugcu ggaaacuuca caccucgccc      960

cucugcacca caaacaccaa agaaggcucc aacaucugcc uaacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucuca uuuuuccccc aggcggagac cugcaaaguc     1080

caauccaacc gcgucuucug cgacaccaug aacucucuua cccucccauc agaaguaaac     1140

cucugcaacg ucgacaucuu uaaccccaaa uacgauugca agauaaugac cuccaaaaca     1200

gacgucucau cguccgucau caccucccua ggagcuaucg ucuccugcua cggcaagacc     1260

aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa ccuucuccaa cgggugcgac     1320

uacgucucua acaaaggcgu ggacacagua uccguaggaa acacacugua cugcguaaac     1380

aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa uuaucaacuu cuacgacccg     1440

cucgucuucc caucagacga guucgacgca uccaucuccc aagucaacga gaaaaucaau     1500

cagucccucg ccuucauacg caaauccgac gaacuccuac auaacguaaa cgccggcaaa     1560

ucuaccacaa acaucaugau cacaaccauc aucaucguaa ucaucgucau ccuucucucg     1620

cucaucgccg uaggacugcu acuuuacugc aaggcccgcu aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2182
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2182
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2183
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2183
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2184
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2184
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2185
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2185
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2186
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2186
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2187
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2187
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2188
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2188
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu caucuuaaaa      120

gcaaacgcaa uaacaacuau ucuaaccgca guaacauuuu guuucgcauc aggacaaaac      180

auaaccgaag aauuuuacca aucaacaugu uccgcaguuu caaaaggaua cuuaggcgca      240

cuaagaacag gcugguacac cuccgugaua acaauagaau uaucaaacau aaaagaaaac      300

aaauguaaug gaacugacgc caaaguaaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cugaacuaca auuacuaaug caauccaccc cagcaacagg cucaggcuca      420

gcaauuugcu ccggagucgc ugucugcaaa guacuacauc uugaaggcga agucaauaaa      480

auaaaaucag cacuucuauc aacaaacaaa gcaguagucu cacuaucaaa cggaguauca      540

guacuaacau uuaaaguauu agaucuaaaa aacuauauag auaaacaacu acuacccaua      600

cucaauaaac aauccuguuc aauaccaaau auagaaaccg uaauagaauu ucaacaaaaa      660

aacaaucgac uauuagaaau cacccgagaa uuuucaguca augcaggcgu aacaacacca      720

guaucaaccu acauguuaac caacuccgaa cuacuauccc ucauaaacga caugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uagucagaca acaaucuuau      840

ucaauaaugu gcaucauaaa agaagaaguu cuagccuacg uaguucaacu uccauuauac      900

ggcguaauug auacaccaug cuggaaacua cacacauccc cacuauguac aacaaacaca      960

aaagaaggau caaacaucug cuuaacuaga acagacagag gaugguacug cgacaacgca     1020

ggaucagucu cauucuuucc acaagcagaa acaugcaagg uccaaucaaa cagaguauuc     1080

ugcgacacaa ugaacuccuu aacacuacca ucugaaguaa accuauguaa uguagacaua     1140

uuuaacccaa aauacgacug caaaauaaug accucaaaaa cagacguauc cucaucagua     1200

auuacaagcc ucggagccau aguaucaugc uacggaaaaa caaaauguac agcaucaaac     1260

aaaaacagag gaauaauaaa aacguucucc aacggaugcg acuauguauc aaacaaaggc     1320

guagacacag uaucagucgg aaauacccuu uacugcguaa acaaacaaga aggccaaagu     1380

cuauacguaa aaggagagcc aauaauaaac uuuuaugacc cccuuguauu cccaucugac     1440

gaauuugaug caucaauauc ccaagucaac gaaaaaauca accaaucauu agccuuuauu     1500

agaaaaagug acgaacuauu acacaacguu aaugcaggga aaucaacaac aaauauaaug     1560

auuacaacca uaauuauagu uaucauaguu auacuacucu cacuaaucgc aguaggauua     1620

cuauuauacu gcaaagcaag auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2189
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2189
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gccaacgcaa ucacaaccau acuuacagcu guuaccuucu gcuucgcauc cggccaaaau      180

aucaccgaag aguucuacca aucaaccugc uccgccguca gcaaaggaua ccucggcgcc      240

cuccgaaccg gaugguacac uucugucauc acaaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg guaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaguacaaa      360

aacgccguca ccgaacugca acuccucaug caauccacac cagcaacggg aucaggaucc      420

gccaucugcu caggcgucgc cgucugcaaa guccugcacc uagaaggaga aguaaacaaa      480

auuaaauccg cccuacucuc caccaacaaa gcagucgucu cacuauccaa cggcgucucc      540

guccucaccu uuaagguccu cgaccucaaa aauuauauag acaaacaacu ccuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac auagaaaccg ucaucgaauu ucaacagaaa      660

aacaaccgac ucuuagaaau uacccgcgag uucagcguca acgccggagu caccacaccc      720

gucucaaccu acaugcucac caacucagaa cuccucucac uaaucaauga uaugcccauc      780

acaaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucgcca acaaagcuac      840

uccaucaugu guaucauuaa agaagaaguc cucgccuacg ucguccaacu uccgcucuac      900

ggcguaaucg acacccccug cuggaaacuu cacaccucgc cccucugcac cacaaacacc      960

aaagaaggcu ccaacaucug ccuaacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu cauuuuuccc ccaggcggag accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucucu uacccuccca ucagaaguaa accucugcaa cgucgacauc     1140

uuuaacccca aauacgauug caagauaaug accuccaaaa cagacgucuc aucguccguc     1200

aucaccuccc uaggagcuau cgucuccugc uacggcaaga ccaaaugcac cgcuuccaac     1260

aaaaaccgcg gcaucaucaa aaccuucucc aacgggugcg acuacgucuc uaacaaaggc     1320

guggacacag uauccguagg aaacacacug uacugcguaa acaaacaaga gggccaaucg     1380

cuuuacguca aaggcgagcc aauuaucaac uucuacgacc cgcucgucuu cccaucagac     1440

gaguucgacg cauccaucuc ccaagucaac gagaaaauca aucagucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acauaacgua aacgccggca aaucuaccac aaacaucaug     1560

aucacaacca ucaucaucgu aaucaucguc auccuucucu cgcucaucgc cguaggacug     1620

cuacuuuacu gcaaggcccg cuaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2190
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2190
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2191
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2191
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2192
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2192
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2193
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2193
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2194
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2194
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2195
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2195
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2196
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2196
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu caucuuaaaa gcaaacgcaa uaacaacuau ucuaaccgca      120

guaacauuuu guuucgcauc aggacaaaac auaaccgaag aauuuuacca aucaacaugu      180

uccgcaguuu caaaaggaua cuuaggcgca cuaagaacag gcugguacac cuccgugaua      240

acaauagaau uaucaaacau aaaagaaaac aaauguaaug gaacugacgc caaaguaaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgcaguaa cugaacuaca auuacuaaug      360

caauccaccc cagcaacagg cucaggcuca gcaauuugcu ccggagucgc ugucugcaaa      420

guacuacauc uugaaggcga agucaauaaa auaaaaucag cacuucuauc aacaaacaaa      480

gcaguagucu cacuaucaaa cggaguauca guacuaacau uuaaaguauu agaucuaaaa      540

aacuauauag auaaacaacu acuacccaua cucaauaaac aauccuguuc aauaccaaau      600

auagaaaccg uaauagaauu ucaacaaaaa aacaaucgac uauuagaaau cacccgagaa      660

uuuucaguca augcaggcgu aacaacacca guaucaaccu acauguuaac caacuccgaa      720

cuacuauccc ucauaaacga caugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uagucagaca acaaucuuau ucaauaaugu gcaucauaaa agaagaaguu      840

cuagccuacg uaguucaacu uccauuauac ggcguaauug auacaccaug cuggaaacua      900

cacacauccc cacuauguac aacaaacaca aaagaaggau caaacaucug cuuaacuaga      960

acagacagag gaugguacug cgacaacgca ggaucagucu cauucuuucc acaagcagaa     1020

acaugcaagg uccaaucaaa cagaguauuc ugcgacacaa ugaacuccuu aacacuacca     1080

ucugaaguaa accuauguaa uguagacaua uuuaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguauc cucaucagua auuacaagcc ucggagccau aguaucaugc     1200

uacggaaaaa caaaauguac agcaucaaac aaaaacagag gaauaauaaa aacguucucc     1260

aacggaugcg acuauguauc aaacaaaggc guagacacag uaucagucgg aaauacccuu     1320

uacugcguaa acaaacaaga aggccaaagu cuauacguaa aaggagagcc aauaauaaac     1380

uuuuaugacc cccuuguauu cccaucugac gaauuugaug caucaauauc ccaagucaac     1440

gaaaaaauca accaaucauu agccuuuauu agaaaaagug acgaacuauu acacaacguu     1500

aaugcaggga aaucaacaac aaauauaaug auuacaacca uaauuauagu uaucauaguu     1560

auacuacucu cacuaaucgc aguaggauua cuauuauacu gcaaagcaag auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2197
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2197
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gccaacgcaa ucacaaccau acuuacagcu      120

guuaccuucu gcuucgcauc cggccaaaau aucaccgaag aguucuacca aucaaccugc      180

uccgccguca gcaaaggaua ccucggcgcc cuccgaaccg gaugguacac uucugucauc      240

acaaucgaac ucuccaacau caaagaaaac aaaugcaacg guaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaguacaaa aacgccguca ccgaacugca acuccucaug      360

caauccacac cagcaacggg aucaggaucc gccaucugcu caggcgucgc cgucugcaaa      420

guccugcacc uagaaggaga aguaaacaaa auuaaauccg cccuacucuc caccaacaaa      480

gcagucgucu cacuauccaa cggcgucucc guccucaccu uuaagguccu cgaccucaaa      540

aauuauauag acaaacaacu ccuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

auagaaaccg ucaucgaauu ucaacagaaa aacaaccgac ucuuagaaau uacccgcgag      660

uucagcguca acgccggagu caccacaccc gucucaaccu acaugcucac caacucagaa      720

cuccucucac uaaucaauga uaugcccauc acaaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucgcca acaaagcuac uccaucaugu guaucauuaa agaagaaguc      840

cucgccuacg ucguccaacu uccgcucuac ggcguaaucg acacccccug cuggaaacuu      900

cacaccucgc cccucugcac cacaaacacc aaagaaggcu ccaacaucug ccuaacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu cauuuuuccc ccaggcggag     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucucu uacccuccca     1080

ucagaaguaa accucugcaa cgucgacauc uuuaacccca aauacgauug caagauaaug     1140

accuccaaaa cagacgucuc aucguccguc aucaccuccc uaggagcuau cgucuccugc     1200

uacggcaaga ccaaaugcac cgcuuccaac aaaaaccgcg gcaucaucaa aaccuucucc     1260

aacgggugcg acuacgucuc uaacaaaggc guggacacag uauccguagg aaacacacug     1320

uacugcguaa acaaacaaga gggccaaucg cuuuacguca aaggcgagcc aauuaucaac     1380

uucuacgacc cgcucgucuu cccaucagac gaguucgacg cauccaucuc ccaagucaac     1440

gagaaaauca aucagucccu cgccuucaua cgcaaauccg acgaacuccu acauaacgua     1500

aacgccggca aaucuaccac aaacaucaug aucacaacca ucaucaucgu aaucaucguc     1560

auccuucucu cgcucaucgc cguaggacug cuacuuuacu gcaaggcccg cuaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2198
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2198
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2199
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2199
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2200
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2200
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2201
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2201
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2202
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2202
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2203
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2203
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2204
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2204
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucaucuu aaaagcaaac gcaauaacaa cuauucuaac cgcaguaaca      180

uuuuguuucg caucaggaca aaacauaacc gaagaauuuu accaaucaac auguuccgca      240

guuucaaaag gauacuuagg cgcacuaaga acaggcuggu acaccuccgu gauaacaaua      300

gaauuaucaa acauaaaaga aaacaaaugu aauggaacug acgccaaagu aaaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacugaac uacaauuacu aaugcaaucc      420

accccagcaa caggcucagg cucagcaauu ugcuccggag ucgcugucug caaaguacua      480

caucuugaag gcgaagucaa uaaaauaaaa ucagcacuuc uaucaacaaa caaagcagua      540

gucucacuau caaacggagu aucaguacua acauuuaaag uauuagaucu aaaaaacuau      600

auagauaaac aacuacuacc cauacucaau aaacaauccu guucaauacc aaauauagaa      660

accguaauag aauuucaaca aaaaaacaau cgacuauuag aaaucacccg agaauuuuca      720

gucaaugcag gcguaacaac accaguauca accuacaugu uaaccaacuc cgaacuacua      780

ucccucauaa acgacaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguca gacaacaauc uuauucaaua augugcauca uaaaagaaga aguucuagcc      900

uacguaguuc aacuuccauu auacggcgua auugauacac caugcuggaa acuacacaca      960

uccccacuau guacaacaaa cacaaaagaa ggaucaaaca ucugcuuaac uagaacagac     1020

agaggauggu acugcgacaa cgcaggauca gucucauucu uuccacaagc agaaacaugc     1080

aagguccaau caaacagagu auucugcgac acaaugaacu ccuuaacacu accaucugaa     1140

guaaaccuau guaauguaga cauauuuaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uauccucauc aguaauuaca agccucggag ccauaguauc augcuacgga     1260

aaaacaaaau guacagcauc aaacaaaaac agaggaauaa uaaaaacguu cuccaacgga     1320

ugcgacuaug uaucaaacaa aggcguagac acaguaucag ucggaaauac ccuuuacugc     1380

guaaacaaac aagaaggcca aagucuauac guaaaaggag agccaauaau aaacuuuuau     1440

gacccccuug uauucccauc ugacgaauuu gaugcaucaa uaucccaagu caacgaaaaa     1500

aucaaccaau cauuagccuu uauuagaaaa agugacgaac uauuacacaa cguuaaugca     1560

gggaaaucaa caacaaauau aaugauuaca accauaauua uaguuaucau aguuauacua     1620

cucucacuaa ucgcaguagg auuacuauua uacugcaaag caagauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2205
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2205
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagccaac gcaaucacaa ccauacuuac agcuguuacc      180

uucugcuucg cauccggcca aaauaucacc gaagaguucu accaaucaac cugcuccgcc      240

gucagcaaag gauaccucgg cgcccuccga accggauggu acacuucugu caucacaauc      300

gaacucucca acaucaaaga aaacaaaugc aacgguaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaagua caaaaacgcc gucaccgaac ugcaacuccu caugcaaucc      420

acaccagcaa cgggaucagg auccgccauc ugcucaggcg ucgccgucug caaaguccug      480

caccuagaag gagaaguaaa caaaauuaaa uccgcccuac ucuccaccaa caaagcaguc      540

gucucacuau ccaacggcgu cuccguccuc accuuuaagg uccucgaccu caaaaauuau      600

auagacaaac aacuccuccc cauccuaaac aaacaaucau gcuccauccc caacauagaa      660

accgucaucg aauuucaaca gaaaaacaac cgacucuuag aaauuacccg cgaguucagc      720

gucaacgccg gagucaccac acccgucuca accuacaugc ucaccaacuc agaacuccuc      780

ucacuaauca augauaugcc caucacaaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gccaacaaag cuacuccauc auguguauca uuaaagaaga aguccucgcc      900

uacgucgucc aacuuccgcu cuacggcgua aucgacaccc ccugcuggaa acuucacacc      960

ucgccccucu gcaccacaaa caccaaagaa ggcuccaaca ucugccuaac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucucauuuu ucccccaggc ggagaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cucuuacccu cccaucagaa     1140

guaaaccucu gcaacgucga caucuuuaac cccaaauacg auugcaagau aaugaccucc     1200

aaaacagacg ucucaucguc cgucaucacc ucccuaggag cuaucgucuc cugcuacggc     1260

aagaccaaau gcaccgcuuc caacaaaaac cgcggcauca ucaaaaccuu cuccaacggg     1320

ugcgacuacg ucucuaacaa aggcguggac acaguauccg uaggaaacac acuguacugc     1380

guaaacaaac aagagggcca aucgcuuuac gucaaaggcg agccaauuau caacuucuac     1440

gacccgcucg ucuucccauc agacgaguuc gacgcaucca ucucccaagu caacgagaaa     1500

aucaaucagu cccucgccuu cauacgcaaa uccgacgaac uccuacauaa cguaaacgcc     1560

ggcaaaucua ccacaaacau caugaucaca accaucauca ucguaaucau cgucauccuu     1620

cucucgcuca ucgccguagg acugcuacuu uacugcaagg cccgcuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2206
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2206
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2207
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2207
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2208
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2208
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2209
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2209
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2210
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2210
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2211
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2211
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2212
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2212
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucaucuuaaa agcaaacgca      120

auaacaacua uucuaaccgc aguaacauuu uguuucgcau caggacaaaa cauaaccgaa      180

gaauuuuacc aaucaacaug uuccgcaguu ucaaaaggau acuuaggcgc acuaagaaca      240

ggcugguaca ccuccgugau aacaauagaa uuaucaaaca uaaaagaaaa caaauguaau      300

ggaacugacg ccaaaguaaa acuaauaaaa caagaacuag acaaauauaa aaacgcagua      360

acugaacuac aauuacuaau gcaauccacc ccagcaacag gcucaggcuc agcaauuugc      420

uccggagucg cugucugcaa aguacuacau cuugaaggcg aagucaauaa aauaaaauca      480

gcacuucuau caacaaacaa agcaguaguc ucacuaucaa acggaguauc aguacuaaca      540

uuuaaaguau uagaucuaaa aaacuauaua gauaaacaac uacuacccau acucaauaaa      600

caauccuguu caauaccaaa uauagaaacc guaauagaau uucaacaaaa aaacaaucga      660

cuauuagaaa ucacccgaga auuuucaguc aaugcaggcg uaacaacacc aguaucaacc      720

uacauguuaa ccaacuccga acuacuaucc cucauaaacg acaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auagucagac aacaaucuua uucaauaaug      840

ugcaucauaa aagaagaagu ucuagccuac guaguucaac uuccauuaua cggcguaauu      900

gauacaccau gcuggaaacu acacacaucc ccacuaugua caacaaacac aaaagaagga      960

ucaaacaucu gcuuaacuag aacagacaga ggaugguacu gcgacaacgc aggaucaguc     1020

ucauucuuuc cacaagcaga aacaugcaag guccaaucaa acagaguauu cugcgacaca     1080

augaacuccu uaacacuacc aucugaagua aaccuaugua auguagacau auuuaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguau ccucaucagu aauuacaagc     1200

cucggagcca uaguaucaug cuacggaaaa acaaaaugua cagcaucaaa caaaaacaga     1260

ggaauaauaa aaacguucuc caacggaugc gacuauguau caaacaaagg cguagacaca     1320

guaucagucg gaaauacccu uuacugcgua aacaaacaag aaggccaaag ucuauacgua     1380

aaaggagagc caauaauaaa cuuuuaugac ccccuuguau ucccaucuga cgaauuugau     1440

gcaucaauau cccaagucaa cgaaaaaauc aaccaaucau uagccuuuau uagaaaaagu     1500

gacgaacuau uacacaacgu uaaugcaggg aaaucaacaa caaauauaau gauuacaacc     1560

auaauuauag uuaucauagu uauacuacuc ucacuaaucg caguaggauu acuauuauac     1620

ugcaaagcaa gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2213
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2213
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agccaacgca      120

aucacaacca uacuuacagc uguuaccuuc ugcuucgcau ccggccaaaa uaucaccgaa      180

gaguucuacc aaucaaccug cuccgccguc agcaaaggau accucggcgc ccuccgaacc      240

ggaugguaca cuucugucau cacaaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

gguaccgacg cgaaagucaa acucaucaaa caagaacuag acaaguacaa aaacgccguc      360

accgaacugc aacuccucau gcaauccaca ccagcaacgg gaucaggauc cgccaucugc      420

ucaggcgucg ccgucugcaa aguccugcac cuagaaggag aaguaaacaa aauuaaaucc      480

gcccuacucu ccaccaacaa agcagucguc ucacuaucca acggcgucuc cguccucacc      540

uuuaaggucc ucgaccucaa aaauuauaua gacaaacaac uccuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa cauagaaacc gucaucgaau uucaacagaa aaacaaccga      660

cucuuagaaa uuacccgcga guucagcguc aacgccggag ucaccacacc cgucucaacc      720

uacaugcuca ccaacucaga acuccucuca cuaaucaaug auaugcccau cacaaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucgcc aacaaagcua cuccaucaug      840

uguaucauua aagaagaagu ccucgccuac gucguccaac uuccgcucua cggcguaauc      900

gacacccccu gcuggaaacu ucacaccucg ccccucugca ccacaaacac caaagaaggc      960

uccaacaucu gccuaacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

ucauuuuucc cccaggcgga gaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucuc uuacccuccc aucagaagua aaccucugca acgucgacau cuuuaacccc     1140

aaauacgauu gcaagauaau gaccuccaaa acagacgucu caucguccgu caucaccucc     1200

cuaggagcua ucgucuccug cuacggcaag accaaaugca ccgcuuccaa caaaaaccgc     1260

ggcaucauca aaaccuucuc caacgggugc gacuacgucu cuaacaaagg cguggacaca     1320

guauccguag gaaacacacu guacugcgua aacaaacaag agggccaauc gcuuuacguc     1380

aaaggcgagc caauuaucaa cuucuacgac ccgcucgucu ucccaucaga cgaguucgac     1440

gcauccaucu cccaagucaa cgagaaaauc aaucaguccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacauaacgu aaacgccggc aaaucuacca caaacaucau gaucacaacc     1560

aucaucaucg uaaucaucgu cauccuucuc ucgcucaucg ccguaggacu gcuacuuuac     1620

ugcaaggccc gcuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2214
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2214
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2215
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2215
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2216
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2216
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2217
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2217
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2218
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2218
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2219
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2219
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2220
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2220
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucaucuuaaa agcaaacgca      120

auaacaacua uucuaaccgc aguaacauuu uguuucgcau caggacaaaa cauaaccgaa      180

gaauuuuacc aaucaacaug uuccgcaguu ucaaaaggau acuuaggcgc acuaagaaca      240

ggcugguaca ccuccgugau aacaauagaa uuaucaaaca uaaaagaaaa caaauguaau      300

ggaacugacg ccaaaguaaa acuaauaaaa caagaacuag acaaauauaa aaacgcagua      360

acugaacuac aauuacuaau gcaauccacc ccagcaacag gcucaggcuc agcaauuugc      420

uccggagucg cugucugcaa aguacuacau cuugaaggcg aagucaauaa aauaaaauca      480

gcacuucuau caacaaacaa agcaguaguc ucacuaucaa acggaguauc aguacuaaca      540

uuuaaaguau uagaucuaaa aaacuauaua gauaaacaac uacuacccau acucaauaaa      600

caauccuguu caauaccaaa uauagaaacc guaauagaau uucaacaaaa aaacaaucga      660

cuauuagaaa ucacccgaga auuuucaguc aaugcaggcg uaacaacacc aguaucaacc      720

uacauguuaa ccaacuccga acuacuaucc cucauaaacg acaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auagucagac aacaaucuua uucaauaaug      840

ugcaucauaa aagaagaagu ucuagccuac guaguucaac uuccauuaua cggcguaauu      900

gauacaccau gcuggaaacu acacacaucc ccacuaugua caacaaacac aaaagaagga      960

ucaaacaucu gcuuaacuag aacagacaga ggaugguacu gcgacaacgc aggaucaguc     1020

ucauucuuuc cacaagcaga aacaugcaag guccaaucaa acagaguauu cugcgacaca     1080

augaacuccu uaacacuacc aucugaagua aaccuaugua auguagacau auuuaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguau ccucaucagu aauuacaagc     1200

cucggagcca uaguaucaug cuacggaaaa acaaaaugua cagcaucaaa caaaaacaga     1260

ggaauaauaa aaacguucuc caacggaugc gacuauguau caaacaaagg cguagacaca     1320

guaucagucg gaaauacccu uuacugcgua aacaaacaag aaggccaaag ucuauacgua     1380

aaaggagagc caauaauaaa cuuuuaugac ccccuuguau ucccaucuga cgaauuugau     1440

gcaucaauau cccaagucaa cgaaaaaauc aaccaaucau uagccuuuau uagaaaaagu     1500

gacgaacuau uacacaacgu uaaugcaggg aaaucaacaa caaauauaau gauuacaacc     1560

auaauuauag uuaucauagu uauacuacuc ucacuaaucg caguaggauu acuauuauac     1620

ugcaaagcaa gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2221
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2221
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agccaacgca      120

aucacaacca uacuuacagc uguuaccuuc ugcuucgcau ccggccaaaa uaucaccgaa      180

gaguucuacc aaucaaccug cuccgccguc agcaaaggau accucggcgc ccuccgaacc      240

ggaugguaca cuucugucau cacaaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

gguaccgacg cgaaagucaa acucaucaaa caagaacuag acaaguacaa aaacgccguc      360

accgaacugc aacuccucau gcaauccaca ccagcaacgg gaucaggauc cgccaucugc      420

ucaggcgucg ccgucugcaa aguccugcac cuagaaggag aaguaaacaa aauuaaaucc      480

gcccuacucu ccaccaacaa agcagucguc ucacuaucca acggcgucuc cguccucacc      540

uuuaaggucc ucgaccucaa aaauuauaua gacaaacaac uccuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa cauagaaacc gucaucgaau uucaacagaa aaacaaccga      660

cucuuagaaa uuacccgcga guucagcguc aacgccggag ucaccacacc cgucucaacc      720

uacaugcuca ccaacucaga acuccucuca cuaaucaaug auaugcccau cacaaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucgcc aacaaagcua cuccaucaug      840

uguaucauua aagaagaagu ccucgccuac gucguccaac uuccgcucua cggcguaauc      900

gacacccccu gcuggaaacu ucacaccucg ccccucugca ccacaaacac caaagaaggc      960

uccaacaucu gccuaacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

ucauuuuucc cccaggcgga gaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucuc uuacccuccc aucagaagua aaccucugca acgucgacau cuuuaacccc     1140

aaauacgauu gcaagauaau gaccuccaaa acagacgucu caucguccgu caucaccucc     1200

cuaggagcua ucgucuccug cuacggcaag accaaaugca ccgcuuccaa caaaaaccgc     1260

ggcaucauca aaaccuucuc caacgggugc gacuacgucu cuaacaaagg cguggacaca     1320

guauccguag gaaacacacu guacugcgua aacaaacaag agggccaauc gcuuuacguc     1380

aaaggcgagc caauuaucaa cuucuacgac ccgcucgucu ucccaucaga cgaguucgac     1440

gcauccaucu cccaagucaa cgagaaaauc aaucaguccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacauaacgu aaacgccggc aaaucuacca caaacaucau gaucacaacc     1560

aucaucaucg uaaucaucgu cauccuucuc ucgcucaucg ccguaggacu gcuacuuuac     1620

ugcaaggccc gcuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2222
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2222
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2223
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2223
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2224
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2224
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2225
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2225
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2226
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2226
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2227
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2227
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2228
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2228
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucaucuuaaa agcaaacgca      120

auaacaacua uucuaaccgc aguaacauuu uguuucgcau caggacaaaa cauaaccgaa      180

gaauuuuacc aaucaacaug uuccgcaguu ucaaaaggau acuuaggcgc acuaagaaca      240

ggcugguaca ccuccgugau aacaauagaa uuaucaaaca uaaaagaaaa caaauguaau      300

ggaacugacg ccaaaguaaa acuaauaaaa caagaacuag acaaauauaa aaacgcagua      360

acugaacuac aauuacuaau gcaauccacc ccagcaacag gcucaggcuc agcaauuugc      420

uccggagucg cugucugcaa aguacuacau cuugaaggcg aagucaauaa aauaaaauca      480

gcacuucuau caacaaacaa agcaguaguc ucacuaucaa acggaguauc aguacuaaca      540

uuuaaaguau uagaucuaaa aaacuauaua gauaaacaac uacuacccau acucaauaaa      600

caauccuguu caauaccaaa uauagaaacc guaauagaau uucaacaaaa aaacaaucga      660

cuauuagaaa ucacccgaga auuuucaguc aaugcaggcg uaacaacacc aguaucaacc      720

uacauguuaa ccaacuccga acuacuaucc cucauaaacg acaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auagucagac aacaaucuua uucaauaaug      840

ugcaucauaa aagaagaagu ucuagccuac guaguucaac uuccauuaua cggcguaauu      900

gauacaccau gcuggaaacu acacacaucc ccacuaugua caacaaacac aaaagaagga      960

ucaaacaucu gcuuaacuag aacagacaga ggaugguacu gcgacaacgc aggaucaguc     1020

ucauucuuuc cacaagcaga aacaugcaag guccaaucaa acagaguauu cugcgacaca     1080

augaacuccu uaacacuacc aucugaagua aaccuaugua auguagacau auuuaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguau ccucaucagu aauuacaagc     1200

cucggagcca uaguaucaug cuacggaaaa acaaaaugua cagcaucaaa caaaaacaga     1260

ggaauaauaa aaacguucuc caacggaugc gacuauguau caaacaaagg cguagacaca     1320

guaucagucg gaaauacccu uuacugcgua aacaaacaag aaggccaaag ucuauacgua     1380

aaaggagagc caauaauaaa cuuuuaugac ccccuuguau ucccaucuga cgaauuugau     1440

gcaucaauau cccaagucaa cgaaaaaauc aaccaaucau uagccuuuau uagaaaaagu     1500

gacgaacuau uacacaacgu uaaugcaggg aaaucaacaa caaauauaau gauuacaacc     1560

auaauuauag uuaucauagu uauacuacuc ucacuaaucg caguaggauu acuauuauac     1620

ugcaaagcaa gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2229
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2229
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agccaacgca      120

aucacaacca uacuuacagc uguuaccuuc ugcuucgcau ccggccaaaa uaucaccgaa      180

gaguucuacc aaucaaccug cuccgccguc agcaaaggau accucggcgc ccuccgaacc      240

ggaugguaca cuucugucau cacaaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

gguaccgacg cgaaagucaa acucaucaaa caagaacuag acaaguacaa aaacgccguc      360

accgaacugc aacuccucau gcaauccaca ccagcaacgg gaucaggauc cgccaucugc      420

ucaggcgucg ccgucugcaa aguccugcac cuagaaggag aaguaaacaa aauuaaaucc      480

gcccuacucu ccaccaacaa agcagucguc ucacuaucca acggcgucuc cguccucacc      540

uuuaaggucc ucgaccucaa aaauuauaua gacaaacaac uccuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa cauagaaacc gucaucgaau uucaacagaa aaacaaccga      660

cucuuagaaa uuacccgcga guucagcguc aacgccggag ucaccacacc cgucucaacc      720

uacaugcuca ccaacucaga acuccucuca cuaaucaaug auaugcccau cacaaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucgcc aacaaagcua cuccaucaug      840

uguaucauua aagaagaagu ccucgccuac gucguccaac uuccgcucua cggcguaauc      900

gacacccccu gcuggaaacu ucacaccucg ccccucugca ccacaaacac caaagaaggc      960

uccaacaucu gccuaacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

ucauuuuucc cccaggcgga gaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucuc uuacccuccc aucagaagua aaccucugca acgucgacau cuuuaacccc     1140

aaauacgauu gcaagauaau gaccuccaaa acagacgucu caucguccgu caucaccucc     1200

cuaggagcua ucgucuccug cuacggcaag accaaaugca ccgcuuccaa caaaaaccgc     1260

ggcaucauca aaaccuucuc caacgggugc gacuacgucu cuaacaaagg cguggacaca     1320

guauccguag gaaacacacu guacugcgua aacaaacaag agggccaauc gcuuuacguc     1380

aaaggcgagc caauuaucaa cuucuacgac ccgcucgucu ucccaucaga cgaguucgac     1440

gcauccaucu cccaagucaa cgagaaaauc aaucaguccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacauaacgu aaacgccggc aaaucuacca caaacaucau gaucacaacc     1560

aucaucaucg uaaucaucgu cauccuucuc ucgcucaucg ccguaggacu gcuacuuuac     1620

ugcaaggccc gcuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2230
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2230
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2231
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2231
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2232
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2232
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2233
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2233
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug aaguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga acuguugucc cucaucaacg acaugcccau uacgaacgau      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gacacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggagggc      960

uccaacauuu guuugacccg aacggaucgu gggugguacu gcgacaaugc aggaagcgug     1020

ucguucuuuc cucaggccga aaccuguaag guucagucua acagaguguu cugcgauaca     1080

augaacuccc uaacucugcc aucagagguc aaucucugca auguggacau cuuuaacccc     1140

aaauaugauu guaagauaau gaccaguaaa acagacguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gauuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccauugguau ucccgaguga ugaguuugac     1440

gcaagcauau cccaggucaa ugaaaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gaugagcugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2234
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2234
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2235
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2235
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aagugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga acugcucagc cugaucaacg acaugccuau uaccaacgau      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gacacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaggga      960

uccaacaucu gucugacacg gaccgaucgc ggcugguacu gcgacaaugc ugggucuguc     1020

uccuucuuuc cucaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucuc uuacccugcc gagcgaggug aaucucugca augucgacau uuuuaacccc     1140

aaauaugauu guaagaucau gaccuccaaa acagacgugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gauuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagaac cuaucauuaa cuuuuacgac ccccucgucu ucccuuccga ugaguuugac     1440

gcuucuauca gccaggugaa ugaaaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gaugagcugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2236
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2236
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucaucuuaaa agcaaacgca      120

auaacaacua uucuaaccgc aguaacauuu uguuucgcau caggacaaaa cauaaccgaa      180

gaauuuuacc aaucaacaug uuccgcaguu ucaaaaggau acuuaggcgc acuaagaaca      240

ggcugguaca ccuccgugau aacaauagaa uuaucaaaca uaaaagaaaa caaauguaau      300

ggaacugacg ccaaaguaaa acuaauaaaa caagaacuag acaaauauaa aaacgcagua      360

acugaacuac aauuacuaau gcaauccacc ccagcaacag gcucaggcuc agcaauuugc      420

uccggagucg cugucugcaa aguacuacau cuugaaggcg aagucaauaa aauaaaauca      480

gcacuucuau caacaaacaa agcaguaguc ucacuaucaa acggaguauc aguacuaaca      540

uuuaaaguau uagaucuaaa aaacuauaua gauaaacaac uacuacccau acucaauaaa      600

caauccuguu caauaccaaa uauagaaacc guaauagaau uucaacaaaa aaacaaucga      660

cuauuagaaa ucacccgaga auuuucaguc aaugcaggcg uaacaacacc aguaucaacc      720

uacauguuaa ccaacuccga acuacuaucc cucauaaacg acaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auagucagac aacaaucuua uucaauaaug      840

ugcaucauaa aagaagaagu ucuagccuac guaguucaac uuccauuaua cggcguaauu      900

gauacaccau gcuggaaacu acacacaucc ccacuaugua caacaaacac aaaagaagga      960

ucaaacaucu gcuuaacuag aacagacaga ggaugguacu gcgacaacgc aggaucaguc     1020

ucauucuuuc cacaagcaga aacaugcaag guccaaucaa acagaguauu cugcgacaca     1080

augaacuccu uaacacuacc aucugaagua aaccuaugua auguagacau auuuaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguau ccucaucagu aauuacaagc     1200

cucggagcca uaguaucaug cuacggaaaa acaaaaugua cagcaucaaa caaaaacaga     1260

ggaauaauaa aaacguucuc caacggaugc gacuauguau caaacaaagg cguagacaca     1320

guaucagucg gaaauacccu uuacugcgua aacaaacaag aaggccaaag ucuauacgua     1380

aaaggagagc caauaauaaa cuuuuaugac ccccuuguau ucccaucuga cgaauuugau     1440

gcaucaauau cccaagucaa cgaaaaaauc aaccaaucau uagccuuuau uagaaaaagu     1500

gacgaacuau uacacaacgu uaaugcaggg aaaucaacaa caaauauaau gauuacaacc     1560

auaauuauag uuaucauagu uauacuacuc ucacuaaucg caguaggauu acuauuauac     1620

ugcaaagcaa gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2237
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2237
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agccaacgca      120

aucacaacca uacuuacagc uguuaccuuc ugcuucgcau ccggccaaaa uaucaccgaa      180

gaguucuacc aaucaaccug cuccgccguc agcaaaggau accucggcgc ccuccgaacc      240

ggaugguaca cuucugucau cacaaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

gguaccgacg cgaaagucaa acucaucaaa caagaacuag acaaguacaa aaacgccguc      360

accgaacugc aacuccucau gcaauccaca ccagcaacgg gaucaggauc cgccaucugc      420

ucaggcgucg ccgucugcaa aguccugcac cuagaaggag aaguaaacaa aauuaaaucc      480

gcccuacucu ccaccaacaa agcagucguc ucacuaucca acggcgucuc cguccucacc      540

uuuaaggucc ucgaccucaa aaauuauaua gacaaacaac uccuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa cauagaaacc gucaucgaau uucaacagaa aaacaaccga      660

cucuuagaaa uuacccgcga guucagcguc aacgccggag ucaccacacc cgucucaacc      720

uacaugcuca ccaacucaga acuccucuca cuaaucaaug auaugcccau cacaaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucgcc aacaaagcua cuccaucaug      840

uguaucauua aagaagaagu ccucgccuac gucguccaac uuccgcucua cggcguaauc      900

gacacccccu gcuggaaacu ucacaccucg ccccucugca ccacaaacac caaagaaggc      960

uccaacaucu gccuaacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

ucauuuuucc cccaggcgga gaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucuc uuacccuccc aucagaagua aaccucugca acgucgacau cuuuaacccc     1140

aaauacgauu gcaagauaau gaccuccaaa acagacgucu caucguccgu caucaccucc     1200

cuaggagcua ucgucuccug cuacggcaag accaaaugca ccgcuuccaa caaaaaccgc     1260

ggcaucauca aaaccuucuc caacgggugc gacuacgucu cuaacaaagg cguggacaca     1320

guauccguag gaaacacacu guacugcgua aacaaacaag agggccaauc gcuuuacguc     1380

aaaggcgagc caauuaucaa cuucuacgac ccgcucgucu ucccaucaga cgaguucgac     1440

gcauccaucu cccaagucaa cgagaaaauc aaucaguccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacauaacgu aaacgccggc aaaucuacca caaacaucau gaucacaacc     1560

aucaucaucg uaaucaucgu cauccuucuc ucgcucaucg ccguaggacu gcuacuuuac     1620

ugcaaggccc gcuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2238
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2238
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2239
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2239
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2240
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2240
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2241
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2241
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2242
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2242
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2243
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2243
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2244
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2244
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc      120

uaaccgcagu aacauuuugu uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau      180

caacauguuc cgcaguuuca aaaggauacu uaggcgcacu aagaacaggc ugguacaccu      240

ccgugauaac aauagaauua ucaaacauaa aagaaaacaa auguaaugga acugacgcca      300

aaguaaaacu aauaaaacaa gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau      360

uacuaaugca auccacccca gcaacaggcu caggcucagc aauuugcucc ggagucgcug      420

ucugcaaagu acuacaucuu gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa      480

caaacaaagc aguagucuca cuaucaaacg gaguaucagu acuaacauuu aaaguauuag      540

aucuaaaaaa cuauauagau aaacaacuac uacccauacu caauaaacaa uccuguucaa      600

uaccaaauau agaaaccgua auagaauuuc aacaaaaaaa caaucgacua uuagaaauca      660

cccgagaauu uucagucaau gcaggcguaa caacaccagu aucaaccuac auguuaacca      720

acuccgaacu acuaucccuc auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua gucagacaac aaucuuauuc aauaaugugc aucauaaaag      840

aagaaguucu agccuacgua guucaacuuc cauuauacgg cguaauugau acaccaugcu      900

ggaaacuaca cacaucccca cuauguacaa caaacacaaa agaaggauca aacaucugcu      960

uaacuagaac agacagagga ugguacugcg acaacgcagg aucagucuca uucuuuccac     1020

aagcagaaac augcaagguc caaucaaaca gaguauucug cgacacaaug aacuccuuaa     1080

cacuaccauc ugaaguaaac cuauguaaug uagacauauu uaacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguauccu caucaguaau uacaagccuc ggagccauag     1200

uaucaugcua cggaaaaaca aaauguacag caucaaacaa aaacagagga auaauaaaaa     1260

cguucuccaa cggaugcgac uauguaucaa acaaaggcgu agacacagua ucagucggaa     1320

auacccuuua cugcguaaac aaacaagaag gccaaagucu auacguaaaa ggagagccaa     1380

uaauaaacuu uuaugacccc cuuguauucc caucugacga auuugaugca ucaauauccc     1440

aagucaacga aaaaaucaac caaucauuag ccuuuauuag aaaaagugac gaacuauuac     1500

acaacguuaa ugcagggaaa ucaacaacaa auauaaugau uacaaccaua auuauaguua     1560

ucauaguuau acuacucuca cuaaucgcag uaggauuacu auuauacugc aaagcaagau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2245
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2245
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc caacgcaauc acaaccauac      120

uuacagcugu uaccuucugc uucgcauccg gccaaaauau caccgaagag uucuaccaau      180

caaccugcuc cgccgucagc aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu      240

cugucaucac aaucgaacuc uccaacauca aagaaaacaa augcaacggu accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aguacaaaaa cgccgucacc gaacugcaac      360

uccucaugca auccacacca gcaacgggau caggauccgc caucugcuca ggcgucgccg      420

ucugcaaagu ccugcaccua gaaggagaag uaaacaaaau uaaauccgcc cuacucucca      480

ccaacaaagc agucgucuca cuauccaacg gcgucuccgu ccucaccuuu aagguccucg      540

accucaaaaa uuauauagac aaacaacucc uccccauccu aaacaaacaa ucaugcucca      600

uccccaacau agaaaccguc aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua      660

cccgcgaguu cagcgucaac gccggaguca ccacacccgu cucaaccuac augcucacca      720

acucagaacu ccucucacua aucaaugaua ugcccaucac aaacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgccaac aaagcuacuc caucaugugu aucauuaaag      840

aagaaguccu cgccuacguc guccaacuuc cgcucuacgg cguaaucgac acccccugcu      900

ggaaacuuca caccucgccc cucugcacca caaacaccaa agaaggcucc aacaucugcc      960

uaacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucuca uuuuuccccc     1020

aggcggagac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucucuua     1080

cccucccauc agaaguaaac cucugcaacg ucgacaucuu uaaccccaaa uacgauugca     1140

agauaaugac cuccaaaaca gacgucucau cguccgucau caccucccua ggagcuaucg     1200

ucuccugcua cggcaagacc aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa     1260

ccuucuccaa cgggugcgac uacgucucua acaaaggcgu ggacacagua uccguaggaa     1320

acacacugua cugcguaaac aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa     1380

uuaucaacuu cuacgacccg cucgucuucc caucagacga guucgacgca uccaucuccc     1440

aagucaacga gaaaaucaau cagucccucg ccuucauacg caaauccgac gaacuccuac     1500

auaacguaaa cgccggcaaa ucuaccacaa acaucaugau cacaaccauc aucaucguaa     1560

ucaucgucau ccuucucucg cucaucgccg uaggacugcu acuuuacugc aaggcccgcu     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2246
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2246
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2247
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2247
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2248
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2248
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2249
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2249
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugaag uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugaacu guugucccuc aucaacgaca ugcccauuac gaacgaucaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cucucuacgg cgucaucgac acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggagggcucc aacauuuguu      960

ugacccgaac ggaucguggg ugguacugcg acaaugcagg aagcgugucg uucuuuccuc     1020

aggccgaaac cuguaagguu cagucuaaca gaguguucug cgauacaaug aacucccuaa     1080

cucugccauc agaggucaau cucugcaaug uggacaucuu uaaccccaaa uaugauugua     1140

agauaaugac caguaaaaca gacguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgau uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgaccca uugguauucc cgagugauga guuugacgca agcauauccc     1440

aggucaauga aaagaucaac cagucucucg cuuucauucg gaaaucggau gagcuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2250
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2250
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2251
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2251
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagaag ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgaacu gcucagccug aucaacgaca ugccuauuac caacgaucaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cccuguacgg ggugaucgac acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggagggaucc aacaucuguc      960

ugacacggac cgaucgcggc ugguacugcg acaaugcugg gucugucucc uucuuuccuc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacucucuua     1080

cccugccgag cgaggugaau cucugcaaug ucgacauuuu uaaccccaaa uaugauugua     1140

agaucaugac cuccaaaaca gacgugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgau uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagaaccua     1380

ucauuaacuu uuacgacccc cucgucuucc cuuccgauga guuugacgcu ucuaucagcc     1440

aggugaauga aaagauuaac cagucccugg ccuucauccg caaaucugau gagcugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2252
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2252
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc      120

uaaccgcagu aacauuuugu uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau      180

caacauguuc cgcaguuuca aaaggauacu uaggcgcacu aagaacaggc ugguacaccu      240

ccgugauaac aauagaauua ucaaacauaa aagaaaacaa auguaaugga acugacgcca      300

aaguaaaacu aauaaaacaa gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau      360

uacuaaugca auccacccca gcaacaggcu caggcucagc aauuugcucc ggagucgcug      420

ucugcaaagu acuacaucuu gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa      480

caaacaaagc aguagucuca cuaucaaacg gaguaucagu acuaacauuu aaaguauuag      540

aucuaaaaaa cuauauagau aaacaacuac uacccauacu caauaaacaa uccuguucaa      600

uaccaaauau agaaaccgua auagaauuuc aacaaaaaaa caaucgacua uuagaaauca      660

cccgagaauu uucagucaau gcaggcguaa caacaccagu aucaaccuac auguuaacca      720

acuccgaacu acuaucccuc auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua gucagacaac aaucuuauuc aauaaugugc aucauaaaag      840

aagaaguucu agccuacgua guucaacuuc cauuauacgg cguaauugau acaccaugcu      900

ggaaacuaca cacaucccca cuauguacaa caaacacaaa agaaggauca aacaucugcu      960

uaacuagaac agacagagga ugguacugcg acaacgcagg aucagucuca uucuuuccac     1020

aagcagaaac augcaagguc caaucaaaca gaguauucug cgacacaaug aacuccuuaa     1080

cacuaccauc ugaaguaaac cuauguaaug uagacauauu uaacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguauccu caucaguaau uacaagccuc ggagccauag     1200

uaucaugcua cggaaaaaca aaauguacag caucaaacaa aaacagagga auaauaaaaa     1260

cguucuccaa cggaugcgac uauguaucaa acaaaggcgu agacacagua ucagucggaa     1320

auacccuuua cugcguaaac aaacaagaag gccaaagucu auacguaaaa ggagagccaa     1380

uaauaaacuu uuaugacccc cuuguauucc caucugacga auuugaugca ucaauauccc     1440

aagucaacga aaaaaucaac caaucauuag ccuuuauuag aaaaagugac gaacuauuac     1500

acaacguuaa ugcagggaaa ucaacaacaa auauaaugau uacaaccaua auuauaguua     1560

ucauaguuau acuacucuca cuaaucgcag uaggauuacu auuauacugc aaagcaagau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2253
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2253
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc caacgcaauc acaaccauac      120

uuacagcugu uaccuucugc uucgcauccg gccaaaauau caccgaagag uucuaccaau      180

caaccugcuc cgccgucagc aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu      240

cugucaucac aaucgaacuc uccaacauca aagaaaacaa augcaacggu accgacgcga      300

aagucaaacu caucaaacaa gaacuagaca aguacaaaaa cgccgucacc gaacugcaac      360

uccucaugca auccacacca gcaacgggau caggauccgc caucugcuca ggcgucgccg      420

ucugcaaagu ccugcaccua gaaggagaag uaaacaaaau uaaauccgcc cuacucucca      480

ccaacaaagc agucgucuca cuauccaacg gcgucuccgu ccucaccuuu aagguccucg      540

accucaaaaa uuauauagac aaacaacucc uccccauccu aaacaaacaa ucaugcucca      600

uccccaacau agaaaccguc aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua      660

cccgcgaguu cagcgucaac gccggaguca ccacacccgu cucaaccuac augcucacca      720

acucagaacu ccucucacua aucaaugaua ugcccaucac aaacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgccaac aaagcuacuc caucaugugu aucauuaaag      840

aagaaguccu cgccuacguc guccaacuuc cgcucuacgg cguaaucgac acccccugcu      900

ggaaacuuca caccucgccc cucugcacca caaacaccaa agaaggcucc aacaucugcc      960

uaacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucuca uuuuuccccc     1020

aggcggagac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucucuua     1080

cccucccauc agaaguaaac cucugcaacg ucgacaucuu uaaccccaaa uacgauugca     1140

agauaaugac cuccaaaaca gacgucucau cguccgucau caccucccua ggagcuaucg     1200

ucuccugcua cggcaagacc aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa     1260

ccuucuccaa cgggugcgac uacgucucua acaaaggcgu ggacacagua uccguaggaa     1320

acacacugua cugcguaaac aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa     1380

uuaucaacuu cuacgacccg cucgucuucc caucagacga guucgacgca uccaucuccc     1440

aagucaacga gaaaaucaau cagucccucg ccuucauacg caaauccgac gaacuccuac     1500

auaacguaaa cgccggcaaa ucuaccacaa acaucaugau cacaaccauc aucaucguaa     1560

ucaucgucau ccuucucucg cucaucgccg uaggacugcu acuuuacugc aaggcccgcu     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2254
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2254
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2255
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2255
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2256
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2256
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2257
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2257
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2258
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2258
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2259
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2259
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2260
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2260
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu caucuuaaaa gcaaacgcaa uaacaacuau ucuaaccgca      120

guaacauuuu guuucgcauc aggacaaaac auaaccgaag aauuuuacca aucaacaugu      180

uccgcaguuu caaaaggaua cuuaggcgca cuaagaacag gcugguacac cuccgugaua      240

acaauagaau uaucaaacau aaaagaaaac aaauguaaug gaacugacgc caaaguaaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgcaguaa cugaacuaca auuacuaaug      360

caauccaccc cagcaacagg cucaggcuca gcaauuugcu ccggagucgc ugucugcaaa      420

guacuacauc uugaaggcga agucaauaaa auaaaaucag cacuucuauc aacaaacaaa      480

gcaguagucu cacuaucaaa cggaguauca guacuaacau uuaaaguauu agaucuaaaa      540

aacuauauag auaaacaacu acuacccaua cucaauaaac aauccuguuc aauaccaaau      600

auagaaaccg uaauagaauu ucaacaaaaa aacaaucgac uauuagaaau cacccgagaa      660

uuuucaguca augcaggcgu aacaacacca guaucaaccu acauguuaac caacuccgaa      720

cuacuauccc ucauaaacga caugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uagucagaca acaaucuuau ucaauaaugu gcaucauaaa agaagaaguu      840

cuagccuacg uaguucaacu uccauuauac ggcguaauug auacaccaug cuggaaacua      900

cacacauccc cacuauguac aacaaacaca aaagaaggau caaacaucug cuuaacuaga      960

acagacagag gaugguacug cgacaacgca ggaucagucu cauucuuucc acaagcagaa     1020

acaugcaagg uccaaucaaa cagaguauuc ugcgacacaa ugaacuccuu aacacuacca     1080

ucugaaguaa accuauguaa uguagacaua uuuaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguauc cucaucagua auuacaagcc ucggagccau aguaucaugc     1200

uacggaaaaa caaaauguac agcaucaaac aaaaacagag gaauaauaaa aacguucucc     1260

aacggaugcg acuauguauc aaacaaaggc guagacacag uaucagucgg aaauacccuu     1320

uacugcguaa acaaacaaga aggccaaagu cuauacguaa aaggagagcc aauaauaaac     1380

uuuuaugacc cccuuguauu cccaucugac gaauuugaug caucaauauc ccaagucaac     1440

gaaaaaauca accaaucauu agccuuuauu agaaaaagug acgaacuauu acacaacguu     1500

aaugcaggga aaucaacaac aaauauaaug auuacaacca uaauuauagu uaucauaguu     1560

auacuacucu cacuaaucgc aguaggauua cuauuauacu gcaaagcaag auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2261
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2261
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gccaacgcaa ucacaaccau acuuacagcu      120

guuaccuucu gcuucgcauc cggccaaaau aucaccgaag aguucuacca aucaaccugc      180

uccgccguca gcaaaggaua ccucggcgcc cuccgaaccg gaugguacac uucugucauc      240

acaaucgaac ucuccaacau caaagaaaac aaaugcaacg guaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaguacaaa aacgccguca ccgaacugca acuccucaug      360

caauccacac cagcaacggg aucaggaucc gccaucugcu caggcgucgc cgucugcaaa      420

guccugcacc uagaaggaga aguaaacaaa auuaaauccg cccuacucuc caccaacaaa      480

gcagucgucu cacuauccaa cggcgucucc guccucaccu uuaagguccu cgaccucaaa      540

aauuauauag acaaacaacu ccuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

auagaaaccg ucaucgaauu ucaacagaaa aacaaccgac ucuuagaaau uacccgcgag      660

uucagcguca acgccggagu caccacaccc gucucaaccu acaugcucac caacucagaa      720

cuccucucac uaaucaauga uaugcccauc acaaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucgcca acaaagcuac uccaucaugu guaucauuaa agaagaaguc      840

cucgccuacg ucguccaacu uccgcucuac ggcguaaucg acacccccug cuggaaacuu      900

cacaccucgc cccucugcac cacaaacacc aaagaaggcu ccaacaucug ccuaacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu cauuuuuccc ccaggcggag     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucucu uacccuccca     1080

ucagaaguaa accucugcaa cgucgacauc uuuaacccca aauacgauug caagauaaug     1140

accuccaaaa cagacgucuc aucguccguc aucaccuccc uaggagcuau cgucuccugc     1200

uacggcaaga ccaaaugcac cgcuuccaac aaaaaccgcg gcaucaucaa aaccuucucc     1260

aacgggugcg acuacgucuc uaacaaaggc guggacacag uauccguagg aaacacacug     1320

uacugcguaa acaaacaaga gggccaaucg cuuuacguca aaggcgagcc aauuaucaac     1380

uucuacgacc cgcucgucuu cccaucagac gaguucgacg cauccaucuc ccaagucaac     1440

gagaaaauca aucagucccu cgccuucaua cgcaaauccg acgaacuccu acauaacgua     1500

aacgccggca aaucuaccac aaacaucaug aucacaacca ucaucaucgu aaucaucguc     1560

auccuucucu cgcucaucgc cguaggacug cuacuuuacu gcaaggcccg cuaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2262
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2262
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2263
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2263
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2264
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2264
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2265
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2265
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga aguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugaa      720

cuguuguccc ucaucaacga caugcccauu acgaacgauc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg acacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggagggcu ccaacauuug uuugacccga      960

acggaucgug ggugguacug cgacaaugca ggaagcgugu cguucuuucc ucaggccgaa     1020

accuguaagg uucagucuaa cagaguguuc ugcgauacaa ugaacucccu aacucugcca     1080

ucagagguca aucucugcaa uguggacauc uuuaacccca aauaugauug uaagauaaug     1140

accaguaaaa cagacguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg auuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cauugguauu cccgagugau gaguuugacg caagcauauc ccaggucaau     1440

gaaaagauca accagucucu cgcuuucauu cggaaaucgg augagcuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2266
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2266
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2267
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2267
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga agugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgaa      720

cugcucagcc ugaucaacga caugccuauu accaacgauc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg acacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggagggau ccaacaucug ucugacacgg      960

accgaucgcg gcugguacug cgacaaugcu gggucugucu ccuucuuucc ucaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacucucu uacccugccg     1080

agcgagguga aucucugcaa ugucgacauu uuuaacccca aauaugauug uaagaucaug     1140

accuccaaaa cagacguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg auuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagaacc uaucauuaac     1380

uuuuacgacc cccucgucuu cccuuccgau gaguuugacg cuucuaucag ccaggugaau     1440

gaaaagauua accagucccu ggccuucauc cgcaaaucug augagcugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2268
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2268
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu caucuuaaaa gcaaacgcaa uaacaacuau ucuaaccgca      120

guaacauuuu guuucgcauc aggacaaaac auaaccgaag aauuuuacca aucaacaugu      180

uccgcaguuu caaaaggaua cuuaggcgca cuaagaacag gcugguacac cuccgugaua      240

acaauagaau uaucaaacau aaaagaaaac aaauguaaug gaacugacgc caaaguaaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgcaguaa cugaacuaca auuacuaaug      360

caauccaccc cagcaacagg cucaggcuca gcaauuugcu ccggagucgc ugucugcaaa      420

guacuacauc uugaaggcga agucaauaaa auaaaaucag cacuucuauc aacaaacaaa      480

gcaguagucu cacuaucaaa cggaguauca guacuaacau uuaaaguauu agaucuaaaa      540

aacuauauag auaaacaacu acuacccaua cucaauaaac aauccuguuc aauaccaaau      600

auagaaaccg uaauagaauu ucaacaaaaa aacaaucgac uauuagaaau cacccgagaa      660

uuuucaguca augcaggcgu aacaacacca guaucaaccu acauguuaac caacuccgaa      720

cuacuauccc ucauaaacga caugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uagucagaca acaaucuuau ucaauaaugu gcaucauaaa agaagaaguu      840

cuagccuacg uaguucaacu uccauuauac ggcguaauug auacaccaug cuggaaacua      900

cacacauccc cacuauguac aacaaacaca aaagaaggau caaacaucug cuuaacuaga      960

acagacagag gaugguacug cgacaacgca ggaucagucu cauucuuucc acaagcagaa     1020

acaugcaagg uccaaucaaa cagaguauuc ugcgacacaa ugaacuccuu aacacuacca     1080

ucugaaguaa accuauguaa uguagacaua uuuaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguauc cucaucagua auuacaagcc ucggagccau aguaucaugc     1200

uacggaaaaa caaaauguac agcaucaaac aaaaacagag gaauaauaaa aacguucucc     1260

aacggaugcg acuauguauc aaacaaaggc guagacacag uaucagucgg aaauacccuu     1320

uacugcguaa acaaacaaga aggccaaagu cuauacguaa aaggagagcc aauaauaaac     1380

uuuuaugacc cccuuguauu cccaucugac gaauuugaug caucaauauc ccaagucaac     1440

gaaaaaauca accaaucauu agccuuuauu agaaaaagug acgaacuauu acacaacguu     1500

aaugcaggga aaucaacaac aaauauaaug auuacaacca uaauuauagu uaucauaguu     1560

auacuacucu cacuaaucgc aguaggauua cuauuauacu gcaaagcaag auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2269
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2269
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gccaacgcaa ucacaaccau acuuacagcu      120

guuaccuucu gcuucgcauc cggccaaaau aucaccgaag aguucuacca aucaaccugc      180

uccgccguca gcaaaggaua ccucggcgcc cuccgaaccg gaugguacac uucugucauc      240

acaaucgaac ucuccaacau caaagaaaac aaaugcaacg guaccgacgc gaaagucaaa      300

cucaucaaac aagaacuaga caaguacaaa aacgccguca ccgaacugca acuccucaug      360

caauccacac cagcaacggg aucaggaucc gccaucugcu caggcgucgc cgucugcaaa      420

guccugcacc uagaaggaga aguaaacaaa auuaaauccg cccuacucuc caccaacaaa      480

gcagucgucu cacuauccaa cggcgucucc guccucaccu uuaagguccu cgaccucaaa      540

aauuauauag acaaacaacu ccuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

auagaaaccg ucaucgaauu ucaacagaaa aacaaccgac ucuuagaaau uacccgcgag      660

uucagcguca acgccggagu caccacaccc gucucaaccu acaugcucac caacucagaa      720

cuccucucac uaaucaauga uaugcccauc acaaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucgcca acaaagcuac uccaucaugu guaucauuaa agaagaaguc      840

cucgccuacg ucguccaacu uccgcucuac ggcguaaucg acacccccug cuggaaacuu      900

cacaccucgc cccucugcac cacaaacacc aaagaaggcu ccaacaucug ccuaacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu cauuuuuccc ccaggcggag     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucucu uacccuccca     1080

ucagaaguaa accucugcaa cgucgacauc uuuaacccca aauacgauug caagauaaug     1140

accuccaaaa cagacgucuc aucguccguc aucaccuccc uaggagcuau cgucuccugc     1200

uacggcaaga ccaaaugcac cgcuuccaac aaaaaccgcg gcaucaucaa aaccuucucc     1260

aacgggugcg acuacgucuc uaacaaaggc guggacacag uauccguagg aaacacacug     1320

uacugcguaa acaaacaaga gggccaaucg cuuuacguca aaggcgagcc aauuaucaac     1380

uucuacgacc cgcucgucuu cccaucagac gaguucgacg cauccaucuc ccaagucaac     1440

gagaaaauca aucagucccu cgccuucaua cgcaaauccg acgaacuccu acauaacgua     1500

aacgccggca aaucuaccac aaacaucaug aucacaacca ucaucaucgu aaucaucguc     1560

auccuucucu cgcucaucgc cguaggacug cuacuuuacu gcaaggcccg cuaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2270
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2270
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2271
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2271
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2272
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2272
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2273
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2273
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2274
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2274
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2275
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2275
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2276
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2276
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau cuuaaaagca      120

aacgcaauaa caacuauucu aaccgcagua acauuuuguu ucgcaucagg acaaaacaua      180

accgaagaau uuuaccaauc aacauguucc gcaguuucaa aaggauacuu aggcgcacua      240

agaacaggcu gguacaccuc cgugauaaca auagaauuau caaacauaaa agaaaacaaa      300

uguaauggaa cugacgccaa aguaaaacua auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacug aacuacaauu acuaaugcaa uccaccccag caacaggcuc aggcucagca      420

auuugcuccg gagucgcugu cugcaaagua cuacaucuug aaggcgaagu caauaaaaua      480

aaaucagcac uucuaucaac aaacaaagca guagucucac uaucaaacgg aguaucagua      540

cuaacauuua aaguauuaga ucuaaaaaac uauauagaua aacaacuacu acccauacuc      600

aauaaacaau ccuguucaau accaaauaua gaaaccguaa uagaauuuca acaaaaaaac      660

aaucgacuau uagaaaucac ccgagaauuu ucagucaaug caggcguaac aacaccagua      720

ucaaccuaca uguuaaccaa cuccgaacua cuaucccuca uaaacgacau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag ucagacaaca aucuuauuca      840

auaaugugca ucauaaaaga agaaguucua gccuacguag uucaacuucc auuauacggc      900

guaauugaua caccaugcug gaaacuacac acauccccac uauguacaac aaacacaaaa      960

gaaggaucaa acaucugcuu aacuagaaca gacagaggau gguacugcga caacgcagga     1020

ucagucucau ucuuuccaca agcagaaaca ugcaaggucc aaucaaacag aguauucugc     1080

gacacaauga acuccuuaac acuaccaucu gaaguaaacc uauguaaugu agacauauuu     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguauccuc aucaguaauu     1200

acaagccucg gagccauagu aucaugcuac ggaaaaacaa aauguacagc aucaaacaaa     1260

aacagaggaa uaauaaaaac guucuccaac ggaugcgacu auguaucaaa caaaggcgua     1320

gacacaguau cagucggaaa uacccuuuac ugcguaaaca aacaagaagg ccaaagucua     1380

uacguaaaag gagagccaau aauaaacuuu uaugaccccc uuguauuccc aucugacgaa     1440

uuugaugcau caauauccca agucaacgaa aaaaucaacc aaucauuagc cuuuauuaga     1500

aaaagugacg aacuauuaca caacguuaau gcagggaaau caacaacaaa uauaaugauu     1560

acaaccauaa uuauaguuau cauaguuaua cuacucucac uaaucgcagu aggauuacua     1620

uuauacugca aagcaagaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2277
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2277
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagcc      120

aacgcaauca caaccauacu uacagcuguu accuucugcu ucgcauccgg ccaaaauauc      180

accgaagagu ucuaccaauc aaccugcucc gccgucagca aaggauaccu cggcgcccuc      240

cgaaccggau gguacacuuc ugucaucaca aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggua ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa guacaaaaac      360

gccgucaccg aacugcaacu ccucaugcaa uccacaccag caacgggauc aggauccgcc      420

aucugcucag gcgucgccgu cugcaaaguc cugcaccuag aaggagaagu aaacaaaauu      480

aaauccgccc uacucuccac caacaaagca gucgucucac uauccaacgg cgucuccguc      540

cucaccuuua agguccucga ccucaaaaau uauauagaca aacaacuccu ccccauccua      600

aacaaacaau caugcuccau ccccaacaua gaaaccguca ucgaauuuca acagaaaaac      660

aaccgacucu uagaaauuac ccgcgaguuc agcgucaacg ccggagucac cacacccguc      720

ucaaccuaca ugcucaccaa cucagaacuc cucucacuaa ucaaugauau gcccaucaca      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgccaaca aagcuacucc      840

aucaugugua ucauuaaaga agaaguccuc gccuacgucg uccaacuucc gcucuacggc      900

guaaucgaca cccccugcug gaaacuucac accucgcccc ucugcaccac aaacaccaaa      960

gaaggcucca acaucugccu aacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucucau uuuuccccca ggcggagacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucucuuac ccucccauca gaaguaaacc ucugcaacgu cgacaucuuu     1140

aaccccaaau acgauugcaa gauaaugacc uccaaaacag acgucucauc guccgucauc     1200

accucccuag gagcuaucgu cuccugcuac ggcaagacca aaugcaccgc uuccaacaaa     1260

aaccgcggca ucaucaaaac cuucuccaac gggugcgacu acgucucuaa caaaggcgug     1320

gacacaguau ccguaggaaa cacacuguac ugcguaaaca aacaagaggg ccaaucgcuu     1380

uacgucaaag gcgagccaau uaucaacuuc uacgacccgc ucgucuuccc aucagacgag     1440

uucgacgcau ccaucuccca agucaacgag aaaaucaauc agucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca uaacguaaac gccggcaaau cuaccacaaa caucaugauc     1560

acaaccauca ucaucguaau caucgucauc cuucucucgc ucaucgccgu aggacugcua     1620

cuuuacugca aggcccgcua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  2278
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2278
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2279
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2279
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2280
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2280
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2281
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2281
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaagu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugaacug uugucccuca ucaacgacau gcccauuacg      780

aacgaucaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaca cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gagggcucca acauuuguuu gacccgaacg gaucgugggu gguacugcga caaugcagga     1020

agcgugucgu ucuuuccuca ggccgaaacc uguaagguuc agucuaacag aguguucugc     1080

gauacaauga acucccuaac ucugccauca gaggucaauc ucugcaaugu ggacaucuuu     1140

aaccccaaau augauuguaa gauaaugacc aguaaaacag acguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgauu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgacccau ugguauuccc gagugaugag     1440

uuugacgcaa gcauauccca ggucaaugaa aagaucaacc agucucucgc uuucauucgg     1500

aaaucggaug agcuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2282
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2282
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2283
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2283
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaagu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgaacug cucagccuga ucaacgacau gccuauuacc      780

aacgaucaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaca caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gagggaucca acaucugucu gacacggacc gaucgcggcu gguacugcga caaugcuggg     1020

ucugucuccu ucuuuccuca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acucucuuac ccugccgagc gaggugaauc ucugcaaugu cgacauuuuu     1140

aaccccaaau augauuguaa gaucaugacc uccaaaacag acgugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgauu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagaaccuau cauuaacuuu uacgaccccc ucgucuuccc uuccgaugag     1440

uuugacgcuu cuaucagcca ggugaaugaa aagauuaacc agucccuggc cuucauccgc     1500

aaaucugaug agcugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2284
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2284
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau cuuaaaagca      120

aacgcaauaa caacuauucu aaccgcagua acauuuuguu ucgcaucagg acaaaacaua      180

accgaagaau uuuaccaauc aacauguucc gcaguuucaa aaggauacuu aggcgcacua      240

agaacaggcu gguacaccuc cgugauaaca auagaauuau caaacauaaa agaaaacaaa      300

uguaauggaa cugacgccaa aguaaaacua auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacug aacuacaauu acuaaugcaa uccaccccag caacaggcuc aggcucagca      420

auuugcuccg gagucgcugu cugcaaagua cuacaucuug aaggcgaagu caauaaaaua      480

aaaucagcac uucuaucaac aaacaaagca guagucucac uaucaaacgg aguaucagua      540

cuaacauuua aaguauuaga ucuaaaaaac uauauagaua aacaacuacu acccauacuc      600

aauaaacaau ccuguucaau accaaauaua gaaaccguaa uagaauuuca acaaaaaaac      660

aaucgacuau uagaaaucac ccgagaauuu ucagucaaug caggcguaac aacaccagua      720

ucaaccuaca uguuaaccaa cuccgaacua cuaucccuca uaaacgacau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag ucagacaaca aucuuauuca      840

auaaugugca ucauaaaaga agaaguucua gccuacguag uucaacuucc auuauacggc      900

guaauugaua caccaugcug gaaacuacac acauccccac uauguacaac aaacacaaaa      960

gaaggaucaa acaucugcuu aacuagaaca gacagaggau gguacugcga caacgcagga     1020

ucagucucau ucuuuccaca agcagaaaca ugcaaggucc aaucaaacag aguauucugc     1080

gacacaauga acuccuuaac acuaccaucu gaaguaaacc uauguaaugu agacauauuu     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguauccuc aucaguaauu     1200

acaagccucg gagccauagu aucaugcuac ggaaaaacaa aauguacagc aucaaacaaa     1260

aacagaggaa uaauaaaaac guucuccaac ggaugcgacu auguaucaaa caaaggcgua     1320

gacacaguau cagucggaaa uacccuuuac ugcguaaaca aacaagaagg ccaaagucua     1380

uacguaaaag gagagccaau aauaaacuuu uaugaccccc uuguauuccc aucugacgaa     1440

uuugaugcau caauauccca agucaacgaa aaaaucaacc aaucauuagc cuuuauuaga     1500

aaaagugacg aacuauuaca caacguuaau gcagggaaau caacaacaaa uauaaugauu     1560

acaaccauaa uuauaguuau cauaguuaua cuacucucac uaaucgcagu aggauuacua     1620

uuauacugca aagcaagaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2285
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2285
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagcc      120

aacgcaauca caaccauacu uacagcuguu accuucugcu ucgcauccgg ccaaaauauc      180

accgaagagu ucuaccaauc aaccugcucc gccgucagca aaggauaccu cggcgcccuc      240

cgaaccggau gguacacuuc ugucaucaca aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggua ccgacgcgaa agucaaacuc aucaaacaag aacuagacaa guacaaaaac      360

gccgucaccg aacugcaacu ccucaugcaa uccacaccag caacgggauc aggauccgcc      420

aucugcucag gcgucgccgu cugcaaaguc cugcaccuag aaggagaagu aaacaaaauu      480

aaauccgccc uacucuccac caacaaagca gucgucucac uauccaacgg cgucuccguc      540

cucaccuuua agguccucga ccucaaaaau uauauagaca aacaacuccu ccccauccua      600

aacaaacaau caugcuccau ccccaacaua gaaaccguca ucgaauuuca acagaaaaac      660

aaccgacucu uagaaauuac ccgcgaguuc agcgucaacg ccggagucac cacacccguc      720

ucaaccuaca ugcucaccaa cucagaacuc cucucacuaa ucaaugauau gcccaucaca      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgccaaca aagcuacucc      840

aucaugugua ucauuaaaga agaaguccuc gccuacgucg uccaacuucc gcucuacggc      900

guaaucgaca cccccugcug gaaacuucac accucgcccc ucugcaccac aaacaccaaa      960

gaaggcucca acaucugccu aacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucucau uuuuccccca ggcggagacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucucuuac ccucccauca gaaguaaacc ucugcaacgu cgacaucuuu     1140

aaccccaaau acgauugcaa gauaaugacc uccaaaacag acgucucauc guccgucauc     1200

accucccuag gagcuaucgu cuccugcuac ggcaagacca aaugcaccgc uuccaacaaa     1260

aaccgcggca ucaucaaaac cuucuccaac gggugcgacu acgucucuaa caaaggcgug     1320

gacacaguau ccguaggaaa cacacuguac ugcguaaaca aacaagaggg ccaaucgcuu     1380

uacgucaaag gcgagccaau uaucaacuuc uacgacccgc ucgucuuccc aucagacgag     1440

uucgacgcau ccaucuccca agucaacgag aaaaucaauc agucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca uaacguaaac gccggcaaau cuaccacaaa caucaugauc     1560

acaaccauca ucaucguaau caucgucauc cuucucucgc ucaucgccgu aggacugcua     1620

cuuuacugca aggcccgcua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  2286
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2286
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2287
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2287
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2288
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2288
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2289
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2289
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug      780

ucccucauca acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau     1020

cguggguggu acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu     1080

aagguucagu cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag     1140

gucaaucucu gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu     1200

aaaacagacg uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgauuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccauugg uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2290
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2290
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2291
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2291
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc      780

agccugauca acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau     1020

cgcggcuggu acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag     1140

gugaaucucu gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc     1200

aaaacagacg ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgauuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac     1440

gacccccucg ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2292
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2292
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucaucuu aaaagcaaac gcaauaacaa cuauucuaac cgcaguaaca      180

uuuuguuucg caucaggaca aaacauaacc gaagaauuuu accaaucaac auguuccgca      240

guuucaaaag gauacuuagg cgcacuaaga acaggcuggu acaccuccgu gauaacaaua      300

gaauuaucaa acauaaaaga aaacaaaugu aauggaacug acgccaaagu aaaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacugaac uacaauuacu aaugcaaucc      420

accccagcaa caggcucagg cucagcaauu ugcuccggag ucgcugucug caaaguacua      480

caucuugaag gcgaagucaa uaaaauaaaa ucagcacuuc uaucaacaaa caaagcagua      540

gucucacuau caaacggagu aucaguacua acauuuaaag uauuagaucu aaaaaacuau      600

auagauaaac aacuacuacc cauacucaau aaacaauccu guucaauacc aaauauagaa      660

accguaauag aauuucaaca aaaaaacaau cgacuauuag aaaucacccg agaauuuuca      720

gucaaugcag gcguaacaac accaguauca accuacaugu uaaccaacuc cgaacuacua      780

ucccucauaa acgacaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguca gacaacaauc uuauucaaua augugcauca uaaaagaaga aguucuagcc      900

uacguaguuc aacuuccauu auacggcgua auugauacac caugcuggaa acuacacaca      960

uccccacuau guacaacaaa cacaaaagaa ggaucaaaca ucugcuuaac uagaacagac     1020

agaggauggu acugcgacaa cgcaggauca gucucauucu uuccacaagc agaaacaugc     1080

aagguccaau caaacagagu auucugcgac acaaugaacu ccuuaacacu accaucugaa     1140

guaaaccuau guaauguaga cauauuuaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uauccucauc aguaauuaca agccucggag ccauaguauc augcuacgga     1260

aaaacaaaau guacagcauc aaacaaaaac agaggaauaa uaaaaacguu cuccaacgga     1320

ugcgacuaug uaucaaacaa aggcguagac acaguaucag ucggaaauac ccuuuacugc     1380

guaaacaaac aagaaggcca aagucuauac guaaaaggag agccaauaau aaacuuuuau     1440

gacccccuug uauucccauc ugacgaauuu gaugcaucaa uaucccaagu caacgaaaaa     1500

aucaaccaau cauuagccuu uauuagaaaa agugacgaac uauuacacaa cguuaaugca     1560

gggaaaucaa caacaaauau aaugauuaca accauaauua uaguuaucau aguuauacua     1620

cucucacuaa ucgcaguagg auuacuauua uacugcaaag caagauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2293
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2293
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagccaac gcaaucacaa ccauacuuac agcuguuacc      180

uucugcuucg cauccggcca aaauaucacc gaagaguucu accaaucaac cugcuccgcc      240

gucagcaaag gauaccucgg cgcccuccga accggauggu acacuucugu caucacaauc      300

gaacucucca acaucaaaga aaacaaaugc aacgguaccg acgcgaaagu caaacucauc      360

aaacaagaac uagacaagua caaaaacgcc gucaccgaac ugcaacuccu caugcaaucc      420

acaccagcaa cgggaucagg auccgccauc ugcucaggcg ucgccgucug caaaguccug      480

caccuagaag gagaaguaaa caaaauuaaa uccgcccuac ucuccaccaa caaagcaguc      540

gucucacuau ccaacggcgu cuccguccuc accuuuaagg uccucgaccu caaaaauuau      600

auagacaaac aacuccuccc cauccuaaac aaacaaucau gcuccauccc caacauagaa      660

accgucaucg aauuucaaca gaaaaacaac cgacucuuag aaauuacccg cgaguucagc      720

gucaacgccg gagucaccac acccgucuca accuacaugc ucaccaacuc agaacuccuc      780

ucacuaauca augauaugcc caucacaaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gccaacaaag cuacuccauc auguguauca uuaaagaaga aguccucgcc      900

uacgucgucc aacuuccgcu cuacggcgua aucgacaccc ccugcuggaa acuucacacc      960

ucgccccucu gcaccacaaa caccaaagaa ggcuccaaca ucugccuaac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucucauuuu ucccccaggc ggagaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cucuuacccu cccaucagaa     1140

guaaaccucu gcaacgucga caucuuuaac cccaaauacg auugcaagau aaugaccucc     1200

aaaacagacg ucucaucguc cgucaucacc ucccuaggag cuaucgucuc cugcuacggc     1260

aagaccaaau gcaccgcuuc caacaaaaac cgcggcauca ucaaaaccuu cuccaacggg     1320

ugcgacuacg ucucuaacaa aggcguggac acaguauccg uaggaaacac acuguacugc     1380

guaaacaaac aagagggcca aucgcuuuac gucaaaggcg agccaauuau caacuucuac     1440

gacccgcucg ucuucccauc agacgaguuc gacgcaucca ucucccaagu caacgagaaa     1500

aucaaucagu cccucgccuu cauacgcaaa uccgacgaac uccuacauaa cguaaacgcc     1560

ggcaaaucua ccacaaacau caugaucaca accaucauca ucguaaucau cgucauccuu     1620

cucucgcuca ucgccguagg acugcuacuu uacugcaagg cccgcuaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2294
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2294
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2295
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2295
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2296
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2296
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2297
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2297
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2298
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2298
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2299
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2299
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2300
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2300
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu caucuuaaaa      120

gcaaacgcaa uaacaacuau ucuaaccgca guaacauuuu guuucgcauc aggacaaaac      180

auaaccgaag aauuuuacca aucaacaugu uccgcaguuu caaaaggaua cuuaggcgca      240

cuaagaacag gcugguacac cuccgugaua acaauagaau uaucaaacau aaaagaaaac      300

aaauguaaug gaacugacgc caaaguaaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cugaacuaca auuacuaaug caauccaccc cagcaacagg cucaggcuca      420

gcaauuugcu ccggagucgc ugucugcaaa guacuacauc uugaaggcga agucaauaaa      480

auaaaaucag cacuucuauc aacaaacaaa gcaguagucu cacuaucaaa cggaguauca      540

guacuaacau uuaaaguauu agaucuaaaa aacuauauag auaaacaacu acuacccaua      600

cucaauaaac aauccuguuc aauaccaaau auagaaaccg uaauagaauu ucaacaaaaa      660

aacaaucgac uauuagaaau cacccgagaa uuuucaguca augcaggcgu aacaacacca      720

guaucaaccu acauguuaac caacuccgaa cuacuauccc ucauaaacga caugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uagucagaca acaaucuuau      840

ucaauaaugu gcaucauaaa agaagaaguu cuagccuacg uaguucaacu uccauuauac      900

ggcguaauug auacaccaug cuggaaacua cacacauccc cacuauguac aacaaacaca      960

aaagaaggau caaacaucug cuuaacuaga acagacagag gaugguacug cgacaacgca     1020

ggaucagucu cauucuuucc acaagcagaa acaugcaagg uccaaucaaa cagaguauuc     1080

ugcgacacaa ugaacuccuu aacacuacca ucugaaguaa accuauguaa uguagacaua     1140

uuuaacccaa aauacgacug caaaauaaug accucaaaaa cagacguauc cucaucagua     1200

auuacaagcc ucggagccau aguaucaugc uacggaaaaa caaaauguac agcaucaaac     1260

aaaaacagag gaauaauaaa aacguucucc aacggaugcg acuauguauc aaacaaaggc     1320

guagacacag uaucagucgg aaauacccuu uacugcguaa acaaacaaga aggccaaagu     1380

cuauacguaa aaggagagcc aauaauaaac uuuuaugacc cccuuguauu cccaucugac     1440

gaauuugaug caucaauauc ccaagucaac gaaaaaauca accaaucauu agccuuuauu     1500

agaaaaagug acgaacuauu acacaacguu aaugcaggga aaucaacaac aaauauaaug     1560

auuacaacca uaauuauagu uaucauaguu auacuacucu cacuaaucgc aguaggauua     1620

cuauuauacu gcaaagcaag auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2301
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2301
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gccaacgcaa ucacaaccau acuuacagcu guuaccuucu gcuucgcauc cggccaaaau      180

aucaccgaag aguucuacca aucaaccugc uccgccguca gcaaaggaua ccucggcgcc      240

cuccgaaccg gaugguacac uucugucauc acaaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg guaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaguacaaa      360

aacgccguca ccgaacugca acuccucaug caauccacac cagcaacggg aucaggaucc      420

gccaucugcu caggcgucgc cgucugcaaa guccugcacc uagaaggaga aguaaacaaa      480

auuaaauccg cccuacucuc caccaacaaa gcagucgucu cacuauccaa cggcgucucc      540

guccucaccu uuaagguccu cgaccucaaa aauuauauag acaaacaacu ccuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac auagaaaccg ucaucgaauu ucaacagaaa      660

aacaaccgac ucuuagaaau uacccgcgag uucagcguca acgccggagu caccacaccc      720

gucucaaccu acaugcucac caacucagaa cuccucucac uaaucaauga uaugcccauc      780

acaaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucgcca acaaagcuac      840

uccaucaugu guaucauuaa agaagaaguc cucgccuacg ucguccaacu uccgcucuac      900

ggcguaaucg acacccccug cuggaaacuu cacaccucgc cccucugcac cacaaacacc      960

aaagaaggcu ccaacaucug ccuaacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu cauuuuuccc ccaggcggag accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucucu uacccuccca ucagaaguaa accucugcaa cgucgacauc     1140

uuuaacccca aauacgauug caagauaaug accuccaaaa cagacgucuc aucguccguc     1200

aucaccuccc uaggagcuau cgucuccugc uacggcaaga ccaaaugcac cgcuuccaac     1260

aaaaaccgcg gcaucaucaa aaccuucucc aacgggugcg acuacgucuc uaacaaaggc     1320

guggacacag uauccguagg aaacacacug uacugcguaa acaaacaaga gggccaaucg     1380

cuuuacguca aaggcgagcc aauuaucaac uucuacgacc cgcucgucuu cccaucagac     1440

gaguucgacg cauccaucuc ccaagucaac gagaaaauca aucagucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acauaacgua aacgccggca aaucuaccac aaacaucaug     1560

aucacaacca ucaucaucgu aaucaucguc auccuucucu cgcucaucgc cguaggacug     1620

cuacuuuacu gcaaggcccg cuaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  2302
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2302
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2303
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2303
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2304
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2304
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2305
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2305
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2306
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2306
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2307
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2307
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2308
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2308
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu caucuuaaaa      120

gcaaacgcaa uaacaacuau ucuaaccgca guaacauuuu guuucgcauc aggacaaaac      180

auaaccgaag aauuuuacca aucaacaugu uccgcaguuu caaaaggaua cuuaggcgca      240

cuaagaacag gcugguacac cuccgugaua acaauagaau uaucaaacau aaaagaaaac      300

aaauguaaug gaacugacgc caaaguaaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cugaacuaca auuacuaaug caauccaccc cagcaacagg cucaggcuca      420

gcaauuugcu ccggagucgc ugucugcaaa guacuacauc uugaaggcga agucaauaaa      480

auaaaaucag cacuucuauc aacaaacaaa gcaguagucu cacuaucaaa cggaguauca      540

guacuaacau uuaaaguauu agaucuaaaa aacuauauag auaaacaacu acuacccaua      600

cucaauaaac aauccuguuc aauaccaaau auagaaaccg uaauagaauu ucaacaaaaa      660

aacaaucgac uauuagaaau cacccgagaa uuuucaguca augcaggcgu aacaacacca      720

guaucaaccu acauguuaac caacuccgaa cuacuauccc ucauaaacga caugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uagucagaca acaaucuuau      840

ucaauaaugu gcaucauaaa agaagaaguu cuagccuacg uaguucaacu uccauuauac      900

ggcguaauug auacaccaug cuggaaacua cacacauccc cacuauguac aacaaacaca      960

aaagaaggau caaacaucug cuuaacuaga acagacagag gaugguacug cgacaacgca     1020

ggaucagucu cauucuuucc acaagcagaa acaugcaagg uccaaucaaa cagaguauuc     1080

ugcgacacaa ugaacuccuu aacacuacca ucugaaguaa accuauguaa uguagacaua     1140

uuuaacccaa aauacgacug caaaauaaug accucaaaaa cagacguauc cucaucagua     1200

auuacaagcc ucggagccau aguaucaugc uacggaaaaa caaaauguac agcaucaaac     1260

aaaaacagag gaauaauaaa aacguucucc aacggaugcg acuauguauc aaacaaaggc     1320

guagacacag uaucagucgg aaauacccuu uacugcguaa acaaacaaga aggccaaagu     1380

cuauacguaa aaggagagcc aauaauaaac uuuuaugacc cccuuguauu cccaucugac     1440

gaauuugaug caucaauauc ccaagucaac gaaaaaauca accaaucauu agccuuuauu     1500

agaaaaagug acgaacuauu acacaacguu aaugcaggga aaucaacaac aaauauaaug     1560

auuacaacca uaauuauagu uaucauaguu auacuacucu cacuaaucgc aguaggauua     1620

cuauuauacu gcaaagcaag auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2309
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2309
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gccaacgcaa ucacaaccau acuuacagcu guuaccuucu gcuucgcauc cggccaaaau      180

aucaccgaag aguucuacca aucaaccugc uccgccguca gcaaaggaua ccucggcgcc      240

cuccgaaccg gaugguacac uucugucauc acaaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg guaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaguacaaa      360

aacgccguca ccgaacugca acuccucaug caauccacac cagcaacggg aucaggaucc      420

gccaucugcu caggcgucgc cgucugcaaa guccugcacc uagaaggaga aguaaacaaa      480

auuaaauccg cccuacucuc caccaacaaa gcagucgucu cacuauccaa cggcgucucc      540

guccucaccu uuaagguccu cgaccucaaa aauuauauag acaaacaacu ccuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac auagaaaccg ucaucgaauu ucaacagaaa      660

aacaaccgac ucuuagaaau uacccgcgag uucagcguca acgccggagu caccacaccc      720

gucucaaccu acaugcucac caacucagaa cuccucucac uaaucaauga uaugcccauc      780

acaaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucgcca acaaagcuac      840

uccaucaugu guaucauuaa agaagaaguc cucgccuacg ucguccaacu uccgcucuac      900

ggcguaaucg acacccccug cuggaaacuu cacaccucgc cccucugcac cacaaacacc      960

aaagaaggcu ccaacaucug ccuaacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu cauuuuuccc ccaggcggag accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucucu uacccuccca ucagaaguaa accucugcaa cgucgacauc     1140

uuuaacccca aauacgauug caagauaaug accuccaaaa cagacgucuc aucguccguc     1200

aucaccuccc uaggagcuau cgucuccugc uacggcaaga ccaaaugcac cgcuuccaac     1260

aaaaaccgcg gcaucaucaa aaccuucucc aacgggugcg acuacgucuc uaacaaaggc     1320

guggacacag uauccguagg aaacacacug uacugcguaa acaaacaaga gggccaaucg     1380

cuuuacguca aaggcgagcc aauuaucaac uucuacgacc cgcucgucuu cccaucagac     1440

gaguucgacg cauccaucuc ccaagucaac gagaaaauca aucagucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acauaacgua aacgccggca aaucuaccac aaacaucaug     1560

aucacaacca ucaucaucgu aaucaucguc auccuucucu cgcucaucgc cguaggacug     1620

cuacuuuacu gcaaggcccg cuaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  2310
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2310
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2311
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2311
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2312
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2312
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2313
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2313
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2314
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2314
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2315
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2315
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2316
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2316
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu caucuuaaaa      120

gcaaacgcaa uaacaacuau ucuaaccgca guaacauuuu guuucgcauc aggacaaaac      180

auaaccgaag aauuuuacca aucaacaugu uccgcaguuu caaaaggaua cuuaggcgca      240

cuaagaacag gcugguacac cuccgugaua acaauagaau uaucaaacau aaaagaaaac      300

aaauguaaug gaacugacgc caaaguaaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cugaacuaca auuacuaaug caauccaccc cagcaacagg cucaggcuca      420

gcaauuugcu ccggagucgc ugucugcaaa guacuacauc uugaaggcga agucaauaaa      480

auaaaaucag cacuucuauc aacaaacaaa gcaguagucu cacuaucaaa cggaguauca      540

guacuaacau uuaaaguauu agaucuaaaa aacuauauag auaaacaacu acuacccaua      600

cucaauaaac aauccuguuc aauaccaaau auagaaaccg uaauagaauu ucaacaaaaa      660

aacaaucgac uauuagaaau cacccgagaa uuuucaguca augcaggcgu aacaacacca      720

guaucaaccu acauguuaac caacuccgaa cuacuauccc ucauaaacga caugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uagucagaca acaaucuuau      840

ucaauaaugu gcaucauaaa agaagaaguu cuagccuacg uaguucaacu uccauuauac      900

ggcguaauug auacaccaug cuggaaacua cacacauccc cacuauguac aacaaacaca      960

aaagaaggau caaacaucug cuuaacuaga acagacagag gaugguacug cgacaacgca     1020

ggaucagucu cauucuuucc acaagcagaa acaugcaagg uccaaucaaa cagaguauuc     1080

ugcgacacaa ugaacuccuu aacacuacca ucugaaguaa accuauguaa uguagacaua     1140

uuuaacccaa aauacgacug caaaauaaug accucaaaaa cagacguauc cucaucagua     1200

auuacaagcc ucggagccau aguaucaugc uacggaaaaa caaaauguac agcaucaaac     1260

aaaaacagag gaauaauaaa aacguucucc aacggaugcg acuauguauc aaacaaaggc     1320

guagacacag uaucagucgg aaauacccuu uacugcguaa acaaacaaga aggccaaagu     1380

cuauacguaa aaggagagcc aauaauaaac uuuuaugacc cccuuguauu cccaucugac     1440

gaauuugaug caucaauauc ccaagucaac gaaaaaauca accaaucauu agccuuuauu     1500

agaaaaagug acgaacuauu acacaacguu aaugcaggga aaucaacaac aaauauaaug     1560

auuacaacca uaauuauagu uaucauaguu auacuacucu cacuaaucgc aguaggauua     1620

cuauuauacu gcaaagcaag auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2317
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2317
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gccaacgcaa ucacaaccau acuuacagcu guuaccuucu gcuucgcauc cggccaaaau      180

aucaccgaag aguucuacca aucaaccugc uccgccguca gcaaaggaua ccucggcgcc      240

cuccgaaccg gaugguacac uucugucauc acaaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg guaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaguacaaa      360

aacgccguca ccgaacugca acuccucaug caauccacac cagcaacggg aucaggaucc      420

gccaucugcu caggcgucgc cgucugcaaa guccugcacc uagaaggaga aguaaacaaa      480

auuaaauccg cccuacucuc caccaacaaa gcagucgucu cacuauccaa cggcgucucc      540

guccucaccu uuaagguccu cgaccucaaa aauuauauag acaaacaacu ccuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac auagaaaccg ucaucgaauu ucaacagaaa      660

aacaaccgac ucuuagaaau uacccgcgag uucagcguca acgccggagu caccacaccc      720

gucucaaccu acaugcucac caacucagaa cuccucucac uaaucaauga uaugcccauc      780

acaaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucgcca acaaagcuac      840

uccaucaugu guaucauuaa agaagaaguc cucgccuacg ucguccaacu uccgcucuac      900

ggcguaaucg acacccccug cuggaaacuu cacaccucgc cccucugcac cacaaacacc      960

aaagaaggcu ccaacaucug ccuaacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu cauuuuuccc ccaggcggag accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucucu uacccuccca ucagaaguaa accucugcaa cgucgacauc     1140

uuuaacccca aauacgauug caagauaaug accuccaaaa cagacgucuc aucguccguc     1200

aucaccuccc uaggagcuau cgucuccugc uacggcaaga ccaaaugcac cgcuuccaac     1260

aaaaaccgcg gcaucaucaa aaccuucucc aacgggugcg acuacgucuc uaacaaaggc     1320

guggacacag uauccguagg aaacacacug uacugcguaa acaaacaaga gggccaaucg     1380

cuuuacguca aaggcgagcc aauuaucaac uucuacgacc cgcucgucuu cccaucagac     1440

gaguucgacg cauccaucuc ccaagucaac gagaaaauca aucagucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acauaacgua aacgccggca aaucuaccac aaacaucaug     1560

aucacaacca ucaucaucgu aaucaucguc auccuucucu cgcucaucgc cguaggacug     1620

cuacuuuacu gcaaggcccg cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  2318
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2318
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2319
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2319
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2320
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2320
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2321
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2321
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga aguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugaa cuguuguccc ucaucaacga caugcccauu      780

acgaacgauc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg acacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggagggcu ccaacauuug uuugacccga acggaucgug ggugguacug cgacaaugca     1020

ggaagcgugu cguucuuucc ucaggccgaa accuguaagg uucagucuaa cagaguguuc     1080

ugcgauacaa ugaacucccu aacucugcca ucagagguca aucucugcaa uguggacauc     1140

uuuaacccca aauaugauug uaagauaaug accaguaaaa cagacguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg auuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cauugguauu cccgagugau     1440

gaguuugacg caagcauauc ccaggucaau gaaaagauca accagucucu cgcuuucauu     1500

cggaaaucgg augagcuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2322
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2322
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2323
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2323
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga agugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgaa cugcucagcc ugaucaacga caugccuauu      780

accaacgauc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg acacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggagggau ccaacaucug ucugacacgg accgaucgcg gcugguacug cgacaaugcu     1020

gggucugucu ccuucuuucc ucaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacucucu uacccugccg agcgagguga aucucugcaa ugucgacauu     1140

uuuaacccca aauaugauug uaagaucaug accuccaaaa cagacguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg auuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagaacc uaucauuaac uuuuacgacc cccucgucuu cccuuccgau     1440

gaguuugacg cuucuaucag ccaggugaau gaaaagauua accagucccu ggccuucauc     1500

cgcaaaucug augagcugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2324
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2324
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu caucuuaaaa      120

gcaaacgcaa uaacaacuau ucuaaccgca guaacauuuu guuucgcauc aggacaaaac      180

auaaccgaag aauuuuacca aucaacaugu uccgcaguuu caaaaggaua cuuaggcgca      240

cuaagaacag gcugguacac cuccgugaua acaauagaau uaucaaacau aaaagaaaac      300

aaauguaaug gaacugacgc caaaguaaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cugaacuaca auuacuaaug caauccaccc cagcaacagg cucaggcuca      420

gcaauuugcu ccggagucgc ugucugcaaa guacuacauc uugaaggcga agucaauaaa      480

auaaaaucag cacuucuauc aacaaacaaa gcaguagucu cacuaucaaa cggaguauca      540

guacuaacau uuaaaguauu agaucuaaaa aacuauauag auaaacaacu acuacccaua      600

cucaauaaac aauccuguuc aauaccaaau auagaaaccg uaauagaauu ucaacaaaaa      660

aacaaucgac uauuagaaau cacccgagaa uuuucaguca augcaggcgu aacaacacca      720

guaucaaccu acauguuaac caacuccgaa cuacuauccc ucauaaacga caugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uagucagaca acaaucuuau      840

ucaauaaugu gcaucauaaa agaagaaguu cuagccuacg uaguucaacu uccauuauac      900

ggcguaauug auacaccaug cuggaaacua cacacauccc cacuauguac aacaaacaca      960

aaagaaggau caaacaucug cuuaacuaga acagacagag gaugguacug cgacaacgca     1020

ggaucagucu cauucuuucc acaagcagaa acaugcaagg uccaaucaaa cagaguauuc     1080

ugcgacacaa ugaacuccuu aacacuacca ucugaaguaa accuauguaa uguagacaua     1140

uuuaacccaa aauacgacug caaaauaaug accucaaaaa cagacguauc cucaucagua     1200

auuacaagcc ucggagccau aguaucaugc uacggaaaaa caaaauguac agcaucaaac     1260

aaaaacagag gaauaauaaa aacguucucc aacggaugcg acuauguauc aaacaaaggc     1320

guagacacag uaucagucgg aaauacccuu uacugcguaa acaaacaaga aggccaaagu     1380

cuauacguaa aaggagagcc aauaauaaac uuuuaugacc cccuuguauu cccaucugac     1440

gaauuugaug caucaauauc ccaagucaac gaaaaaauca accaaucauu agccuuuauu     1500

agaaaaagug acgaacuauu acacaacguu aaugcaggga aaucaacaac aaauauaaug     1560

auuacaacca uaauuauagu uaucauaguu auacuacucu cacuaaucgc aguaggauua     1620

cuauuauacu gcaaagcaag auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2325
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2325
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gccaacgcaa ucacaaccau acuuacagcu guuaccuucu gcuucgcauc cggccaaaau      180

aucaccgaag aguucuacca aucaaccugc uccgccguca gcaaaggaua ccucggcgcc      240

cuccgaaccg gaugguacac uucugucauc acaaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg guaccgacgc gaaagucaaa cucaucaaac aagaacuaga caaguacaaa      360

aacgccguca ccgaacugca acuccucaug caauccacac cagcaacggg aucaggaucc      420

gccaucugcu caggcgucgc cgucugcaaa guccugcacc uagaaggaga aguaaacaaa      480

auuaaauccg cccuacucuc caccaacaaa gcagucgucu cacuauccaa cggcgucucc      540

guccucaccu uuaagguccu cgaccucaaa aauuauauag acaaacaacu ccuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac auagaaaccg ucaucgaauu ucaacagaaa      660

aacaaccgac ucuuagaaau uacccgcgag uucagcguca acgccggagu caccacaccc      720

gucucaaccu acaugcucac caacucagaa cuccucucac uaaucaauga uaugcccauc      780

acaaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucgcca acaaagcuac      840

uccaucaugu guaucauuaa agaagaaguc cucgccuacg ucguccaacu uccgcucuac      900

ggcguaaucg acacccccug cuggaaacuu cacaccucgc cccucugcac cacaaacacc      960

aaagaaggcu ccaacaucug ccuaacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu cauuuuuccc ccaggcggag accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucucu uacccuccca ucagaaguaa accucugcaa cgucgacauc     1140

uuuaacccca aauacgauug caagauaaug accuccaaaa cagacgucuc aucguccguc     1200

aucaccuccc uaggagcuau cgucuccugc uacggcaaga ccaaaugcac cgcuuccaac     1260

aaaaaccgcg gcaucaucaa aaccuucucc aacgggugcg acuacgucuc uaacaaaggc     1320

guggacacag uauccguagg aaacacacug uacugcguaa acaaacaaga gggccaaucg     1380

cuuuacguca aaggcgagcc aauuaucaac uucuacgacc cgcucgucuu cccaucagac     1440

gaguucgacg cauccaucuc ccaagucaac gagaaaauca aucagucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acauaacgua aacgccggca aaucuaccac aaacaucaug     1560

aucacaacca ucaucaucgu aaucaucguc auccuucucu cgcucaucgc cguaggacug     1620

cuacuuuacu gcaaggcccg cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2326
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2326
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2327
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2327
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2328
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2328
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2329
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2329
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2330
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2330
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2331
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2331
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2332
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2332
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucu uaaaagcaaa cgcaauaaca acuauucuaa ccgcaguaac auuuuguuuc      240

gcaucaggac aaaacauaac cgaagaauuu uaccaaucaa cauguuccgc aguuucaaaa      300

ggauacuuag gcgcacuaag aacaggcugg uacaccuccg ugauaacaau agaauuauca      360

aacauaaaag aaaacaaaug uaauggaacu gacgccaaag uaaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacugaa cuacaauuac uaaugcaauc caccccagca      480

acaggcucag gcucagcaau uugcuccgga gucgcugucu gcaaaguacu acaucuugaa      540

ggcgaaguca auaaaauaaa aucagcacuu cuaucaacaa acaaagcagu agucucacua      600

ucaaacggag uaucaguacu aacauuuaaa guauuagauc uaaaaaacua uauagauaaa      660

caacuacuac ccauacucaa uaaacaaucc uguucaauac caaauauaga aaccguaaua      720

gaauuucaac aaaaaaacaa ucgacuauua gaaaucaccc gagaauuuuc agucaaugca      780

ggcguaacaa caccaguauc aaccuacaug uuaaccaacu ccgaacuacu aucccucaua      840

aacgacaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauaguc      900

agacaacaau cuuauucaau aaugugcauc auaaaagaag aaguucuagc cuacguaguu      960

caacuuccau uauacggcgu aauugauaca ccaugcugga aacuacacac auccccacua     1020

uguacaacaa acacaaaaga aggaucaaac aucugcuuaa cuagaacaga cagaggaugg     1080

uacugcgaca acgcaggauc agucucauuc uuuccacaag cagaaacaug caagguccaa     1140

ucaaacagag uauucugcga cacaaugaac uccuuaacac uaccaucuga aguaaaccua     1200

uguaauguag acauauuuaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guauccucau caguaauuac aagccucgga gccauaguau caugcuacgg aaaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaaua auaaaaacgu ucuccaacgg augcgacuau     1380

guaucaaaca aaggcguaga cacaguauca gucggaaaua cccuuuacug cguaaacaaa     1440

caagaaggcc aaagucuaua cguaaaagga gagccaauaa uaaacuuuua ugacccccuu     1500

guauucccau cugacgaauu ugaugcauca auaucccaag ucaacgaaaa aaucaaccaa     1560

ucauuagccu uuauuagaaa aagugacgaa cuauuacaca acguuaaugc agggaaauca     1620

acaacaaaua uaaugauuac aaccauaauu auaguuauca uaguuauacu acucucacua     1680

aucgcaguag gauuacuauu auacugcaaa gcaagauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2333
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2333
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagccaa cgcaaucaca accauacuua cagcuguuac cuucugcuuc      240

gcauccggcc aaaauaucac cgaagaguuc uaccaaucaa ccugcuccgc cgucagcaaa      300

ggauaccucg gcgcccuccg aaccggaugg uacacuucug ucaucacaau cgaacucucc      360

aacaucaaag aaaacaaaug caacgguacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaagu acaaaaacgc cgucaccgaa cugcaacucc ucaugcaauc cacaccagca      480

acgggaucag gauccgccau cugcucaggc gucgccgucu gcaaaguccu gcaccuagaa      540

ggagaaguaa acaaaauuaa auccgcccua cucuccacca acaaagcagu cgucucacua      600

uccaacggcg ucuccguccu caccuuuaag guccucgacc ucaaaaauua uauagacaaa      660

caacuccucc ccauccuaaa caaacaauca ugcuccaucc ccaacauaga aaccgucauc      720

gaauuucaac agaaaaacaa ccgacucuua gaaauuaccc gcgaguucag cgucaacgcc      780

ggagucacca cacccgucuc aaccuacaug cucaccaacu cagaacuccu cucacuaauc      840

aaugauaugc ccaucacaaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgccaacaaa gcuacuccau cauguguauc auuaaagaag aaguccucgc cuacgucguc      960

caacuuccgc ucuacggcgu aaucgacacc cccugcugga aacuucacac cucgccccuc     1020

ugcaccacaa acaccaaaga aggcuccaac aucugccuaa cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucucauuu uucccccagg cggagaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucucuuaccc ucccaucaga aguaaaccuc     1200

ugcaacgucg acaucuuuaa ccccaaauac gauugcaaga uaaugaccuc caaaacagac     1260

gucucaucgu ccgucaucac cucccuagga gcuaucgucu ccugcuacgg caagaccaaa     1320

ugcaccgcuu ccaacaaaaa ccgcggcauc aucaaaaccu ucuccaacgg gugcgacuac     1380

gucucuaaca aaggcgugga cacaguaucc guaggaaaca cacuguacug cguaaacaaa     1440

caagagggcc aaucgcuuua cgucaaaggc gagccaauua ucaacuucua cgacccgcuc     1500

gucuucccau cagacgaguu cgacgcaucc aucucccaag ucaacgagaa aaucaaucag     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaua acguaaacgc cggcaaaucu     1620

accacaaaca ucaugaucac aaccaucauc aucguaauca ucgucauccu ucucucgcuc     1680

aucgccguag gacugcuacu uuacugcaag gcccgcuaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2334
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2334
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2335
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2335
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2336
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2336
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2337
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2337
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2338
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2338
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2339
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2339
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2340
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2340
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucu uaaaagcaaa cgcaauaaca acuauucuaa ccgcaguaac auuuuguuuc      240

gcaucaggac aaaacauaac cgaagaauuu uaccaaucaa cauguuccgc aguuucaaaa      300

ggauacuuag gcgcacuaag aacaggcugg uacaccuccg ugauaacaau agaauuauca      360

aacauaaaag aaaacaaaug uaauggaacu gacgccaaag uaaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacugaa cuacaauuac uaaugcaauc caccccagca      480

acaggcucag gcucagcaau uugcuccgga gucgcugucu gcaaaguacu acaucuugaa      540

ggcgaaguca auaaaauaaa aucagcacuu cuaucaacaa acaaagcagu agucucacua      600

ucaaacggag uaucaguacu aacauuuaaa guauuagauc uaaaaaacua uauagauaaa      660

caacuacuac ccauacucaa uaaacaaucc uguucaauac caaauauaga aaccguaaua      720

gaauuucaac aaaaaaacaa ucgacuauua gaaaucaccc gagaauuuuc agucaaugca      780

ggcguaacaa caccaguauc aaccuacaug uuaaccaacu ccgaacuacu aucccucaua      840

aacgacaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauaguc      900

agacaacaau cuuauucaau aaugugcauc auaaaagaag aaguucuagc cuacguaguu      960

caacuuccau uauacggcgu aauugauaca ccaugcugga aacuacacac auccccacua     1020

uguacaacaa acacaaaaga aggaucaaac aucugcuuaa cuagaacaga cagaggaugg     1080

uacugcgaca acgcaggauc agucucauuc uuuccacaag cagaaacaug caagguccaa     1140

ucaaacagag uauucugcga cacaaugaac uccuuaacac uaccaucuga aguaaaccua     1200

uguaauguag acauauuuaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guauccucau caguaauuac aagccucgga gccauaguau caugcuacgg aaaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaaua auaaaaacgu ucuccaacgg augcgacuau     1380

guaucaaaca aaggcguaga cacaguauca gucggaaaua cccuuuacug cguaaacaaa     1440

caagaaggcc aaagucuaua cguaaaagga gagccaauaa uaaacuuuua ugacccccuu     1500

guauucccau cugacgaauu ugaugcauca auaucccaag ucaacgaaaa aaucaaccaa     1560

ucauuagccu uuauuagaaa aagugacgaa cuauuacaca acguuaaugc agggaaauca     1620

acaacaaaua uaaugauuac aaccauaauu auaguuauca uaguuauacu acucucacua     1680

aucgcaguag gauuacuauu auacugcaaa gcaagauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2341
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2341
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagccaa cgcaaucaca accauacuua cagcuguuac cuucugcuuc      240

gcauccggcc aaaauaucac cgaagaguuc uaccaaucaa ccugcuccgc cgucagcaaa      300

ggauaccucg gcgcccuccg aaccggaugg uacacuucug ucaucacaau cgaacucucc      360

aacaucaaag aaaacaaaug caacgguacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaagu acaaaaacgc cgucaccgaa cugcaacucc ucaugcaauc cacaccagca      480

acgggaucag gauccgccau cugcucaggc gucgccgucu gcaaaguccu gcaccuagaa      540

ggagaaguaa acaaaauuaa auccgcccua cucuccacca acaaagcagu cgucucacua      600

uccaacggcg ucuccguccu caccuuuaag guccucgacc ucaaaaauua uauagacaaa      660

caacuccucc ccauccuaaa caaacaauca ugcuccaucc ccaacauaga aaccgucauc      720

gaauuucaac agaaaaacaa ccgacucuua gaaauuaccc gcgaguucag cgucaacgcc      780

ggagucacca cacccgucuc aaccuacaug cucaccaacu cagaacuccu cucacuaauc      840

aaugauaugc ccaucacaaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgccaacaaa gcuacuccau cauguguauc auuaaagaag aaguccucgc cuacgucguc      960

caacuuccgc ucuacggcgu aaucgacacc cccugcugga aacuucacac cucgccccuc     1020

ugcaccacaa acaccaaaga aggcuccaac aucugccuaa cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucucauuu uucccccagg cggagaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucucuuaccc ucccaucaga aguaaaccuc     1200

ugcaacgucg acaucuuuaa ccccaaauac gauugcaaga uaaugaccuc caaaacagac     1260

gucucaucgu ccgucaucac cucccuagga gcuaucgucu ccugcuacgg caagaccaaa     1320

ugcaccgcuu ccaacaaaaa ccgcggcauc aucaaaaccu ucuccaacgg gugcgacuac     1380

gucucuaaca aaggcgugga cacaguaucc guaggaaaca cacuguacug cguaaacaaa     1440

caagagggcc aaucgcuuua cgucaaaggc gagccaauua ucaacuucua cgacccgcuc     1500

gucuucccau cagacgaguu cgacgcaucc aucucccaag ucaacgagaa aaucaaucag     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaua acguaaacgc cggcaaaucu     1620

accacaaaca ucaugaucac aaccaucauc aucguaauca ucgucauccu ucucucgcuc     1680

aucgccguag gacugcuacu uuacugcaag gcccgcuaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  2342
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2342
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2343
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2343
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2344
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2344
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2345
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2345
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugaaguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugaacuguu gucccucauc      840

aacgacaugc ccauuacgaa cgaucaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgacacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga gggcuccaac auuuguuuga cccgaacgga ucgugggugg     1080

uacugcgaca augcaggaag cgugucguuc uuuccucagg ccgaaaccug uaagguucag     1140

ucuaacagag uguucugcga uacaaugaac ucccuaacuc ugccaucaga ggucaaucuc     1200

ugcaaugugg acaucuuuaa ccccaaauau gauuguaaga uaaugaccag uaaaacagac     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgauuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gaaccuauca uuaacuuuua cgacccauug     1500

guauucccga gugaugaguu ugacgcaagc auaucccagg ucaaugaaaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggaugag cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2346
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2346
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2347
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2347
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagaaguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgaacugcu cagccugauc      840

aacgacaugc cuauuaccaa cgaucaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgacaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga gggauccaac aucugucuga cacggaccga ucgcggcugg     1080

uacugcgaca augcuggguc ugucuccuuc uuuccucagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac ucucuuaccc ugccgagcga ggugaaucuc     1200

ugcaaugucg acauuuuuaa ccccaaauau gauuguaaga ucaugaccuc caaaacagac     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgauuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gaaccuauca uuaacuuuua cgacccccuc     1500

gucuucccuu ccgaugaguu ugacgcuucu aucagccagg ugaaugaaaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugaugag cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2348
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2348
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucu uaaaagcaaa cgcaauaaca acuauucuaa ccgcaguaac auuuuguuuc      240

gcaucaggac aaaacauaac cgaagaauuu uaccaaucaa cauguuccgc aguuucaaaa      300

ggauacuuag gcgcacuaag aacaggcugg uacaccuccg ugauaacaau agaauuauca      360

aacauaaaag aaaacaaaug uaauggaacu gacgccaaag uaaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacugaa cuacaauuac uaaugcaauc caccccagca      480

acaggcucag gcucagcaau uugcuccgga gucgcugucu gcaaaguacu acaucuugaa      540

ggcgaaguca auaaaauaaa aucagcacuu cuaucaacaa acaaagcagu agucucacua      600

ucaaacggag uaucaguacu aacauuuaaa guauuagauc uaaaaaacua uauagauaaa      660

caacuacuac ccauacucaa uaaacaaucc uguucaauac caaauauaga aaccguaaua      720

gaauuucaac aaaaaaacaa ucgacuauua gaaaucaccc gagaauuuuc agucaaugca      780

ggcguaacaa caccaguauc aaccuacaug uuaaccaacu ccgaacuacu aucccucaua      840

aacgacaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauaguc      900

agacaacaau cuuauucaau aaugugcauc auaaaagaag aaguucuagc cuacguaguu      960

caacuuccau uauacggcgu aauugauaca ccaugcugga aacuacacac auccccacua     1020

uguacaacaa acacaaaaga aggaucaaac aucugcuuaa cuagaacaga cagaggaugg     1080

uacugcgaca acgcaggauc agucucauuc uuuccacaag cagaaacaug caagguccaa     1140

ucaaacagag uauucugcga cacaaugaac uccuuaacac uaccaucuga aguaaaccua     1200

uguaauguag acauauuuaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guauccucau caguaauuac aagccucgga gccauaguau caugcuacgg aaaaacaaaa     1320

uguacagcau caaacaaaaa cagaggaaua auaaaaacgu ucuccaacgg augcgacuau     1380

guaucaaaca aaggcguaga cacaguauca gucggaaaua cccuuuacug cguaaacaaa     1440

caagaaggcc aaagucuaua cguaaaagga gagccaauaa uaaacuuuua ugacccccuu     1500

guauucccau cugacgaauu ugaugcauca auaucccaag ucaacgaaaa aaucaaccaa     1560

ucauuagccu uuauuagaaa aagugacgaa cuauuacaca acguuaaugc agggaaauca     1620

acaacaaaua uaaugauuac aaccauaauu auaguuauca uaguuauacu acucucacua     1680

aucgcaguag gauuacuauu auacugcaaa gcaagauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2349
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2349
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagccaa cgcaaucaca accauacuua cagcuguuac cuucugcuuc      240

gcauccggcc aaaauaucac cgaagaguuc uaccaaucaa ccugcuccgc cgucagcaaa      300

ggauaccucg gcgcccuccg aaccggaugg uacacuucug ucaucacaau cgaacucucc      360

aacaucaaag aaaacaaaug caacgguacc gacgcgaaag ucaaacucau caaacaagaa      420

cuagacaagu acaaaaacgc cgucaccgaa cugcaacucc ucaugcaauc cacaccagca      480

acgggaucag gauccgccau cugcucaggc gucgccgucu gcaaaguccu gcaccuagaa      540

ggagaaguaa acaaaauuaa auccgcccua cucuccacca acaaagcagu cgucucacua      600

uccaacggcg ucuccguccu caccuuuaag guccucgacc ucaaaaauua uauagacaaa      660

caacuccucc ccauccuaaa caaacaauca ugcuccaucc ccaacauaga aaccgucauc      720

gaauuucaac agaaaaacaa ccgacucuua gaaauuaccc gcgaguucag cgucaacgcc      780

ggagucacca cacccgucuc aaccuacaug cucaccaacu cagaacuccu cucacuaauc      840

aaugauaugc ccaucacaaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgccaacaaa gcuacuccau cauguguauc auuaaagaag aaguccucgc cuacgucguc      960

caacuuccgc ucuacggcgu aaucgacacc cccugcugga aacuucacac cucgccccuc     1020

ugcaccacaa acaccaaaga aggcuccaac aucugccuaa cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucucauuu uucccccagg cggagaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucucuuaccc ucccaucaga aguaaaccuc     1200

ugcaacgucg acaucuuuaa ccccaaauac gauugcaaga uaaugaccuc caaaacagac     1260

gucucaucgu ccgucaucac cucccuagga gcuaucgucu ccugcuacgg caagaccaaa     1320

ugcaccgcuu ccaacaaaaa ccgcggcauc aucaaaaccu ucuccaacgg gugcgacuac     1380

gucucuaaca aaggcgugga cacaguaucc guaggaaaca cacuguacug cguaaacaaa     1440

caagagggcc aaucgcuuua cgucaaaggc gagccaauua ucaacuucua cgacccgcuc     1500

gucuucccau cagacgaguu cgacgcaucc aucucccaag ucaacgagaa aaucaaucag     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaua acguaaacgc cggcaaaucu     1620

accacaaaca ucaugaucac aaccaucauc aucguaauca ucgucauccu ucucucgcuc     1680

aucgccguag gacugcuacu uuacugcaag gcccgcuaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2350
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2350
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2351
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2351
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2352
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2352
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2353
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2353
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugaag uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugaacu guugucccuc      720

aucaacgaca ugcccauuac gaacgaucaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgac acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggagggcucc aacauuuguu ugacccgaac ggaucguggg      960

ugguacugcg acaaugcagg aagcgugucg uucuuuccuc aggccgaaac cuguaagguu     1020

cagucuaaca gaguguucug cgauacaaug aacucccuaa cucugccauc agaggucaau     1080

cucugcaaug uggacaucuu uaaccccaaa uaugauugua agauaaugac caguaaaaca     1140

gacguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgau     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagaaccua ucauuaacuu uuacgaccca     1380

uugguauucc cgagugauga guuugacgca agcauauccc aggucaauga aaagaucaac     1440

cagucucucg cuuucauucg gaaaucggau gagcuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2354
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2354
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2355
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2355
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagaag ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgaacu gcucagccug      720

aucaacgaca ugccuauuac caacgaucaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgac acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggagggaucc aacaucuguc ugacacggac cgaucgcggc      960

ugguacugcg acaaugcugg gucugucucc uucuuuccuc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacucucuua cccugccgag cgaggugaau     1080

cucugcaaug ucgacauuuu uaaccccaaa uaugauugua agaucaugac cuccaaaaca     1140

gacgugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgau     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagaaccua ucauuaacuu uuacgacccc     1380

cucgucuucc cuuccgauga guuugacgcu ucuaucagcc aggugaauga aaagauuaac     1440

cagucccugg ccuucauccg caaaucugau gagcugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2356
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2356
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuca ucuuaaaagc aaacgcaaua acaacuauuc uaaccgcagu aacauuuugu      120

uucgcaucag gacaaaacau aaccgaagaa uuuuaccaau caacauguuc cgcaguuuca      180

aaaggauacu uaggcgcacu aagaacaggc ugguacaccu ccgugauaac aauagaauua      240

ucaaacauaa aagaaaacaa auguaaugga acugacgcca aaguaaaacu aauaaaacaa      300

gaacuagaca aauauaaaaa cgcaguaacu gaacuacaau uacuaaugca auccacccca      360

gcaacaggcu caggcucagc aauuugcucc ggagucgcug ucugcaaagu acuacaucuu      420

gaaggcgaag ucaauaaaau aaaaucagca cuucuaucaa caaacaaagc aguagucuca      480

cuaucaaacg gaguaucagu acuaacauuu aaaguauuag aucuaaaaaa cuauauagau      540

aaacaacuac uacccauacu caauaaacaa uccuguucaa uaccaaauau agaaaccgua      600

auagaauuuc aacaaaaaaa caaucgacua uuagaaauca cccgagaauu uucagucaau      660

gcaggcguaa caacaccagu aucaaccuac auguuaacca acuccgaacu acuaucccuc      720

auaaacgaca ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      780

gucagacaac aaucuuauuc aauaaugugc aucauaaaag aagaaguucu agccuacgua      840

guucaacuuc cauuauacgg cguaauugau acaccaugcu ggaaacuaca cacaucccca      900

cuauguacaa caaacacaaa agaaggauca aacaucugcu uaacuagaac agacagagga      960

ugguacugcg acaacgcagg aucagucuca uucuuuccac aagcagaaac augcaagguc     1020

caaucaaaca gaguauucug cgacacaaug aacuccuuaa cacuaccauc ugaaguaaac     1080

cuauguaaug uagacauauu uaacccaaaa uacgacugca aaauaaugac cucaaaaaca     1140

gacguauccu caucaguaau uacaagccuc ggagccauag uaucaugcua cggaaaaaca     1200

aaauguacag caucaaacaa aaacagagga auaauaaaaa cguucuccaa cggaugcgac     1260

uauguaucaa acaaaggcgu agacacagua ucagucggaa auacccuuua cugcguaaac     1320

aaacaagaag gccaaagucu auacguaaaa ggagagccaa uaauaaacuu uuaugacccc     1380

cuuguauucc caucugacga auuugaugca ucaauauccc aagucaacga aaaaaucaac     1440

caaucauuag ccuuuauuag aaaaagugac gaacuauuac acaacguuaa ugcagggaaa     1500

ucaacaacaa auauaaugau uacaaccaua auuauaguua ucauaguuau acuacucuca     1560

cuaaucgcag uaggauuacu auuauacugc aaagcaagau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2357
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2357
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuca uccuaaaagc caacgcaauc acaaccauac uuacagcugu uaccuucugc      120

uucgcauccg gccaaaauau caccgaagag uucuaccaau caaccugcuc cgccgucagc      180

aaaggauacc ucggcgcccu ccgaaccgga ugguacacuu cugucaucac aaucgaacuc      240

uccaacauca aagaaaacaa augcaacggu accgacgcga aagucaaacu caucaaacaa      300

gaacuagaca aguacaaaaa cgccgucacc gaacugcaac uccucaugca auccacacca      360

gcaacgggau caggauccgc caucugcuca ggcgucgccg ucugcaaagu ccugcaccua      420

gaaggagaag uaaacaaaau uaaauccgcc cuacucucca ccaacaaagc agucgucuca      480

cuauccaacg gcgucuccgu ccucaccuuu aagguccucg accucaaaaa uuauauagac      540

aaacaacucc uccccauccu aaacaaacaa ucaugcucca uccccaacau agaaaccguc      600

aucgaauuuc aacagaaaaa caaccgacuc uuagaaauua cccgcgaguu cagcgucaac      660

gccggaguca ccacacccgu cucaaccuac augcucacca acucagaacu ccucucacua      720

aucaaugaua ugcccaucac aaacgaccaa aagaaacuca uguccaacaa cguacaaauc      780

guucgccaac aaagcuacuc caucaugugu aucauuaaag aagaaguccu cgccuacguc      840

guccaacuuc cgcucuacgg cguaaucgac acccccugcu ggaaacuuca caccucgccc      900

cucugcacca caaacaccaa agaaggcucc aacaucugcc uaacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucuca uuuuuccccc aggcggagac cugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucucuua cccucccauc agaaguaaac     1080

cucugcaacg ucgacaucuu uaaccccaaa uacgauugca agauaaugac cuccaaaaca     1140

gacgucucau cguccgucau caccucccua ggagcuaucg ucuccugcua cggcaagacc     1200

aaaugcaccg cuuccaacaa aaaccgcggc aucaucaaaa ccuucuccaa cgggugcgac     1260

uacgucucua acaaaggcgu ggacacagua uccguaggaa acacacugua cugcguaaac     1320

aaacaagagg gccaaucgcu uuacgucaaa ggcgagccaa uuaucaacuu cuacgacccg     1380

cucgucuucc caucagacga guucgacgca uccaucuccc aagucaacga gaaaaucaau     1440

cagucccucg ccuucauacg caaauccgac gaacuccuac auaacguaaa cgccggcaaa     1500

ucuaccacaa acaucaugau cacaaccauc aucaucguaa ucaucgucau ccuucucucg     1560

cucaucgccg uaggacugcu acuuuacugc aaggcccgcu aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  2358
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2358
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2359
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2359
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug gucagccucu      480

ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug agccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac cggggcuggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag gucaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc gucaacaagc     1320

aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac gacccccugg     1380

uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2360
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2360
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2361
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2361
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug caccucgagg      420

gugaaguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug gucucccucu      480

cuaacggggu gagcguauua acuuuuaagg uucuggaccu uaagaauuac auugauaaac      540

aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgag accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu gucaacgccg      660

gagugacuac cccggugagc acauauaugc uuaccaauuc ugaacuguug ucccucauca      720

acgacaugcc cauuacgaac gaucaaaaga aacugauguc aaauaacguc cagaucguuc      780

gccagcagag cuacaguauc augugcauua uaaaggagga aguguuagcg uauguagugc      840

aacugccucu cuacggcguc aucgacacuc cauguuggaa acuucauaca ucuccccugu      900

gcaccacuaa uacaaaggag ggcuccaaca uuuguuugac ccgaacggau cguggguggu      960

acugcgacaa ugcaggaagc gugucguucu uuccucaggc cgaaaccugu aagguucagu     1020

cuaacagagu guucugcgau acaaugaacu cccuaacucu gccaucagag gucaaucucu     1080

gcaaugugga caucuuuaac cccaaauaug auuguaagau aaugaccagu aaaacagacg     1140

uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc aagaccaaau     1200

guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga ugcgauuaug     1260

ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu guuaacaagc     1320

aagaggggca gucacuguau gugaaaggag aaccuaucau uaacuuuuac gacccauugg     1380

uauucccgag ugaugaguuu gacgcaagca uaucccaggu caaugaaaag aucaaccagu     1440

cucucgcuuu cauucggaaa ucggaugagc uguuacacaa ugugaacgcc ggcaagagca     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaucccuca     1560

ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2362
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2362
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2363
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2363
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc caccuggagg      420

gagaagugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc gugucucucu      480

ccaacggcgu uagcgugcug acauuuaagg uccuugaccu gaagaauuac auugauaaac      540

aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgag accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc gugaacgcug      660

gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgaacugcuc agccugauca      720

acgacaugcc uauuaccaac gaucaaaaga aacuuauguc caauaacgug cagaucguga      780

gacagcaguc uuacagcauu augugcauca uuaaggagga aguccuggcc uaugugguuc      840

aacucccccu guacggggug aucgacacac cuuguuggaa acugcauacg agcccccucu      900

gcaccacaaa uaccaaggag ggauccaaca ucugucugac acggaccgau cgcggcuggu      960

acugcgacaa ugcugggucu gucuccuucu uuccucaggc cgaaacgugu aaggugcaga     1020

gcaacagagu uuucugcgau acaaugaacu cucuuacccu gccgagcgag gugaaucucu     1080

gcaaugucga cauuuuuaac cccaaauaug auuguaagau caugaccucc aaaacagacg     1140

ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc aagacaaaau     1200

guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga ugcgauuaug     1260

uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu guuaacaagc     1320

aagaggggca gagccuguau gugaaaggag aaccuaucau uaacuuuuac gacccccucg     1380

ucuucccuuc cgaugaguuu gacgcuucua ucagccaggu gaaugaaaag auuaaccagu     1440

cccuggccuu cauccgcaaa ucugaugagc ugcuccacaa ugugaacgcu ggcaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucccuga     1560

ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2364
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2364
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacucaucuu aaaagcaaac gcaauaacaa cuauucuaac cgcaguaaca uuuuguuucg      120

caucaggaca aaacauaacc gaagaauuuu accaaucaac auguuccgca guuucaaaag      180

gauacuuagg cgcacuaaga acaggcuggu acaccuccgu gauaacaaua gaauuaucaa      240

acauaaaaga aaacaaaugu aauggaacug acgccaaagu aaaacuaaua aaacaagaac      300

uagacaaaua uaaaaacgca guaacugaac uacaauuacu aaugcaaucc accccagcaa      360

caggcucagg cucagcaauu ugcuccggag ucgcugucug caaaguacua caucuugaag      420

gcgaagucaa uaaaauaaaa ucagcacuuc uaucaacaaa caaagcagua gucucacuau      480

caaacggagu aucaguacua acauuuaaag uauuagaucu aaaaaacuau auagauaaac      540

aacuacuacc cauacucaau aaacaauccu guucaauacc aaauauagaa accguaauag      600

aauuucaaca aaaaaacaau cgacuauuag aaaucacccg agaauuuuca gucaaugcag      660

gcguaacaac accaguauca accuacaugu uaaccaacuc cgaacuacua ucccucauaa      720

acgacaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua caaauaguca      780

gacaacaauc uuauucaaua augugcauca uaaaagaaga aguucuagcc uacguaguuc      840

aacuuccauu auacggcgua auugauacac caugcuggaa acuacacaca uccccacuau      900

guacaacaaa cacaaaagaa ggaucaaaca ucugcuuaac uagaacagac agaggauggu      960

acugcgacaa cgcaggauca gucucauucu uuccacaagc agaaacaugc aagguccaau     1020

caaacagagu auucugcgac acaaugaacu ccuuaacacu accaucugaa guaaaccuau     1080

guaauguaga cauauuuaac ccaaaauacg acugcaaaau aaugaccuca aaaacagacg     1140

uauccucauc aguaauuaca agccucggag ccauaguauc augcuacgga aaaacaaaau     1200

guacagcauc aaacaaaaac agaggaauaa uaaaaacguu cuccaacgga ugcgacuaug     1260

uaucaaacaa aggcguagac acaguaucag ucggaaauac ccuuuacugc guaaacaaac     1320

aagaaggcca aagucuauac guaaaaggag agccaauaau aaacuuuuau gacccccuug     1380

uauucccauc ugacgaauuu gaugcaucaa uaucccaagu caacgaaaaa aucaaccaau     1440

cauuagccuu uauuagaaaa agugacgaac uauuacacaa cguuaaugca gggaaaucaa     1500

caacaaauau aaugauuaca accauaauua uaguuaucau aguuauacua cucucacuaa     1560

ucgcaguagg auuacuauua uacugcaaag caagauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2365
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2365
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacucauccu aaaagccaac gcaaucacaa ccauacuuac agcuguuacc uucugcuucg      120

cauccggcca aaauaucacc gaagaguucu accaaucaac cugcuccgcc gucagcaaag      180

gauaccucgg cgcccuccga accggauggu acacuucugu caucacaauc gaacucucca      240

acaucaaaga aaacaaaugc aacgguaccg acgcgaaagu caaacucauc aaacaagaac      300

uagacaagua caaaaacgcc gucaccgaac ugcaacuccu caugcaaucc acaccagcaa      360

cgggaucagg auccgccauc ugcucaggcg ucgccgucug caaaguccug caccuagaag      420

gagaaguaaa caaaauuaaa uccgcccuac ucuccaccaa caaagcaguc gucucacuau      480

ccaacggcgu cuccguccuc accuuuaagg uccucgaccu caaaaauuau auagacaaac      540

aacuccuccc cauccuaaac aaacaaucau gcuccauccc caacauagaa accgucaucg      600

aauuucaaca gaaaaacaac cgacucuuag aaauuacccg cgaguucagc gucaacgccg      660

gagucaccac acccgucuca accuacaugc ucaccaacuc agaacuccuc ucacuaauca      720

augauaugcc caucacaaac gaccaaaaga aacucauguc caacaacgua caaaucguuc      780

gccaacaaag cuacuccauc auguguauca uuaaagaaga aguccucgcc uacgucgucc      840

aacuuccgcu cuacggcgua aucgacaccc ccugcuggaa acuucacacc ucgccccucu      900

gcaccacaaa caccaaagaa ggcuccaaca ucugccuaac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucucauuuu ucccccaggc ggagaccugc aaaguccaau     1020

ccaaccgcgu cuucugcgac accaugaacu cucuuacccu cccaucagaa guaaaccucu     1080

gcaacgucga caucuuuaac cccaaauacg auugcaagau aaugaccucc aaaacagacg     1140

ucucaucguc cgucaucacc ucccuaggag cuaucgucuc cugcuacggc aagaccaaau     1200

gcaccgcuuc caacaaaaac cgcggcauca ucaaaaccuu cuccaacggg ugcgacuacg     1260

ucucuaacaa aggcguggac acaguauccg uaggaaacac acuguacugc guaaacaaac     1320

aagagggcca aucgcuuuac gucaaaggcg agccaauuau caacuucuac gacccgcucg     1380

ucuucccauc agacgaguuc gacgcaucca ucucccaagu caacgagaaa aucaaucagu     1440

cccucgccuu cauacgcaaa uccgacgaac uccuacauaa cguaaacgcc ggcaaaucua     1500

ccacaaacau caugaucaca accaucauca ucguaaucau cgucauccuu cucucgcuca     1560

ucgccguagg acugcuacuu uacugcaagg cccgcuaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  2366
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1) R6774

<400>  2366
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2367
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt1)

<400>  2367
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucugcuccgg cguggccgug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcgcu gcuguccacc      420

aacaaggccg uggucagccu cuccaacggc gugagcgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcaguc cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcucaccaac      660

uccgagcugc ugagccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccg cuguacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggguccaa caucugccug      900

acccgcaccg accggggcug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cucccguccg aggucaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccucuacu gcgucaacaa gcaggagggc cagagccugu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccccu gguguucccg agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cgggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug gggcuccugc uguacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2368
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt2)

<400>  2368
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2369
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt3)

<400>  2369
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua uauguucagg cguggcaguc      360

ugcaaggugu ugcaccucga gggugaaguu aacaaaauca agagcgcccu gcugaguacg      420

aauaaagcug uggucucccu cucuaacggg gugagcguau uaacuuuuaa gguucuggac      480

cuuaagaauu acauugauaa acaauugcug ccuauccuaa acaagcaguc cuguucaauu      540

ccaaauaucg agaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuua gugucaacgc cggagugacu accccgguga gcacauauau gcuuaccaau      660

ucugaacugu ugucccucau caacgacaug cccauuacga acgaucaaaa gaaacugaug      720

ucaaauaacg uccagaucgu ucgccagcag agcuacagua ucaugugcau uauaaaggag      780

gaaguguuag cguauguagu gcaacugccu cucuacggcg ucaucgacac uccauguugg      840

aaacuucaua caucuccccu gugcaccacu aauacaaagg agggcuccaa cauuuguuug      900

acccgaacgg aucgugggug guacugcgac aaugcaggaa gcgugucguu cuuuccucag      960

gccgaaaccu guaagguuca gucuaacaga guguucugcg auacaaugaa cucccuaacu     1020

cugccaucag aggucaaucu cugcaaugug gacaucuuua accccaaaua ugauuguaag     1080

auaaugacca guaaaacaga cguaagcucc ucuguuauua cuagccuggg ugcuaucgug     1140

ucaugcuacg gcaagaccaa auguacagcc aguaauaaga acagggggau cauuaagacc     1200

uucuccaaug gaugcgauua ugucagcaac aaaggcgugg acacugucuc uguggguaau     1260

acgcuuuacu guguuaacaa gcaagagggg cagucacugu augugaaagg agaaccuauc     1320

auuaacuuuu acgacccauu gguauucccg agugaugagu uugacgcaag cauaucccag     1380

gucaaugaaa agaucaacca gucucucgcu uucauucgga aaucggauga gcuguuacac     1440

aaugugaacg ccggcaagag cacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaucccu caucgcgguc ggccugcuuu uguauugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2370
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt4)

<400>  2370
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2371
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt5)

<400>  2371
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaauaaau gcaacgggac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua uuuguagcgg ggucgccgug      360

ugcaagguuc uccaccugga gggagaagug aacaaaauca aguccgcgcu ucugagcacc      420

aauaaagccg ucgugucucu cuccaacggc guuagcgugc ugacauuuaa gguccuugac      480

cugaagaauu acauugauaa acaacuccug ccuauccuga acaagcaguc uuguuccauu      540

ccgaauaucg agaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuua gcgugaacgc uggcgucaca acccccguuu cuacauauau gcuuaccaau      660

uccgaacugc ucagccugau caacgacaug ccuauuacca acgaucaaaa gaaacuuaug      720

uccaauaacg ugcagaucgu gagacagcag ucuuacagca uuaugugcau cauuaaggag      780

gaaguccugg ccuauguggu ucaacucccc cuguacgggg ugaucgacac accuuguugg      840

aaacugcaua cgagcccccu cugcaccaca aauaccaagg agggauccaa caucugucug      900

acacggaccg aucgcggcug guacugcgac aaugcugggu cugucuccuu cuuuccucag      960

gccgaaacgu guaaggugca gagcaacaga guuuucugcg auacaaugaa cucucuuacc     1020

cugccgagcg aggugaaucu cugcaauguc gacauuuuua accccaaaua ugauuguaag     1080

aucaugaccu ccaaaacaga cgugucuagc uccgucauua ccagccuggg agcgaucgug     1140

ucuugcuacg gcaagacaaa auguacggcc uccaauaaga accgggggau uaucaagacc     1200

uucagcaaug gaugcgauua uguuucuaac aaaggcgugg acacagucuc cgugggcaau     1260

acccuuuacu guguuaacaa gcaagagggg cagagccugu augugaaagg agaaccuauc     1320

auuaacuuuu acgacccccu cgucuucccu uccgaugagu uugacgcuuc uaucagccag     1380

gugaaugaaa agauuaacca gucccuggcc uucauccgca aaucugauga gcugcuccac     1440

aaugugaacg cuggcaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucccu gaucgccgug gggcuccugc uguauugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2372
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt6)

<400>  2372
gggagaaagc uuaccaugga acuacucauc uuaaaagcaa acgcaauaac aacuauucua       60

accgcaguaa cauuuuguuu cgcaucagga caaaacauaa ccgaagaauu uuaccaauca      120

acauguuccg caguuucaaa aggauacuua ggcgcacuaa gaacaggcug guacaccucc      180

gugauaacaa uagaauuauc aaacauaaaa gaaaacaaau guaauggaac ugacgccaaa      240

guaaaacuaa uaaaacaaga acuagacaaa uauaaaaacg caguaacuga acuacaauua      300

cuaaugcaau ccaccccagc aacaggcuca ggcucagcaa uuugcuccgg agucgcuguc      360

ugcaaaguac uacaucuuga aggcgaaguc aauaaaauaa aaucagcacu ucuaucaaca      420

aacaaagcag uagucucacu aucaaacgga guaucaguac uaacauuuaa aguauuagau      480

cuaaaaaacu auauagauaa acaacuacua cccauacuca auaaacaauc cuguucaaua      540

ccaaauauag aaaccguaau agaauuucaa caaaaaaaca aucgacuauu agaaaucacc      600

cgagaauuuu cagucaaugc aggcguaaca acaccaguau caaccuacau guuaaccaac      660

uccgaacuac uaucccucau aaacgacaug ccaauaacaa acgaucaaaa aaaacuaaug      720

uccaacaacg uacaaauagu cagacaacaa ucuuauucaa uaaugugcau cauaaaagaa      780

gaaguucuag ccuacguagu ucaacuucca uuauacggcg uaauugauac accaugcugg      840

aaacuacaca cauccccacu auguacaaca aacacaaaag aaggaucaaa caucugcuua      900

acuagaacag acagaggaug guacugcgac aacgcaggau cagucucauu cuuuccacaa      960

gcagaaacau gcaaggucca aucaaacaga guauucugcg acacaaugaa cuccuuaaca     1020

cuaccaucug aaguaaaccu auguaaugua gacauauuua acccaaaaua cgacugcaaa     1080

auaaugaccu caaaaacaga cguauccuca ucaguaauua caagccucgg agccauagua     1140

ucaugcuacg gaaaaacaaa auguacagca ucaaacaaaa acagaggaau aauaaaaacg     1200

uucuccaacg gaugcgacua uguaucaaac aaaggcguag acacaguauc agucggaaau     1260

acccuuuacu gcguaaacaa acaagaaggc caaagucuau acguaaaagg agagccaaua     1320

auaaacuuuu augacccccu uguauuccca ucugacgaau uugaugcauc aauaucccaa     1380

gucaacgaaa aaaucaacca aucauuagcc uuuauuagaa aaagugacga acuauuacac     1440

aacguuaaug cagggaaauc aacaacaaau auaaugauua caaccauaau uauaguuauc     1500

auaguuauac uacucucacu aaucgcagua ggauuacuau uauacugcaa agcaagauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2373
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut1 (opt11)

<400>  2373
gggagaaagc uuaccaugga acuacucauc cuaaaagcca acgcaaucac aaccauacuu       60

acagcuguua ccuucugcuu cgcauccggc caaaauauca ccgaagaguu cuaccaauca      120

accugcuccg ccgucagcaa aggauaccuc ggcgcccucc gaaccggaug guacacuucu      180

gucaucacaa ucgaacucuc caacaucaaa gaaaacaaau gcaacgguac cgacgcgaaa      240

gucaaacuca ucaaacaaga acuagacaag uacaaaaacg ccgucaccga acugcaacuc      300

cucaugcaau ccacaccagc aacgggauca ggauccgcca ucugcucagg cgucgccguc      360

ugcaaagucc ugcaccuaga aggagaagua aacaaaauua aauccgcccu acucuccacc      420

aacaaagcag ucgucucacu auccaacggc gucuccgucc ucaccuuuaa gguccucgac      480

cucaaaaauu auauagacaa acaacuccuc cccauccuaa acaaacaauc augcuccauc      540

cccaacauag aaaccgucau cgaauuucaa cagaaaaaca accgacucuu agaaauuacc      600

cgcgaguuca gcgucaacgc cggagucacc acacccgucu caaccuacau gcucaccaac      660

ucagaacucc ucucacuaau caaugauaug cccaucacaa acgaccaaaa gaaacucaug      720

uccaacaacg uacaaaucgu ucgccaacaa agcuacucca ucauguguau cauuaaagaa      780

gaaguccucg ccuacgucgu ccaacuuccg cucuacggcg uaaucgacac ccccugcugg      840

aaacuucaca ccucgccccu cugcaccaca aacaccaaag aaggcuccaa caucugccua      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucucauu uuucccccag      960

gcggagaccu gcaaagucca auccaaccgc gucuucugcg acaccaugaa cucucuuacc     1020

cucccaucag aaguaaaccu cugcaacguc gacaucuuua accccaaaua cgauugcaag     1080

auaaugaccu ccaaaacaga cgucucaucg uccgucauca ccucccuagg agcuaucguc     1140

uccugcuacg gcaagaccaa augcaccgcu uccaacaaaa accgcggcau caucaaaacc     1200

uucuccaacg ggugcgacua cgucucuaac aaaggcgugg acacaguauc cguaggaaac     1260

acacuguacu gcguaaacaa acaagagggc caaucgcuuu acgucaaagg cgagccaauu     1320

aucaacuucu acgacccgcu cgucuuccca ucagacgagu ucgacgcauc caucucccaa     1380

gucaacgaga aaaucaauca gucccucgcc uucauacgca aauccgacga acuccuacau     1440

aacguaaacg ccggcaaauc uaccacaaac aucaugauca caaccaucau caucguaauc     1500

aucgucaucc uucucucgcu caucgccgua ggacugcuac uuuacugcaa ggcccgcuaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  2374
<211>  535
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2374

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly Ile 
        515                 520                 525             


Asn Asn Ile Ala Phe Ser Asn 
    530                 535 


<210>  2375
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2375
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1560

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacuga                  1608


<210>  2376
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2376
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucugc uccggcgugg ccgugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcgcugcugu ccaccaacaa ggccgugguc      420

agccucucca acggcgugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccgcugua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      900

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu cuacugcguc     1260

aacaagcagg agggccagag ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguccacccc cgugacccug     1560

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  2377
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2377
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1560

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacuga                  1608


<210>  2378
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2378
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugaccugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuauaugu ucaggcgugg cagucugcaa gguguugcac      360

cucgagggug agguuaacaa aaucaagagc gcccugcuga guacgaauaa agcugugguc      420

ucccucucua acggggugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauu      480

gacaaacaau ugcugccuau ccuaaacaag caguccuguu caauuccaaa uaucgaaacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuaguguc      600

aacgccggag ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      660

cucaucaacg auaugcccau uacgaacgac caaaagaaac ugaugucaaa uaacguccag      720

aucguucgcc agcagagcua caguaucaug ugcauuauaa aggaagaggu guuagcguau      780

guagugcaac ugccucucua cggcgucauc gauacuccau guuggaaacu ucauacaucu      840

ccccugugca ccacuaauac aaaggaaggc uccaacauuu guuugacccg aacggaccgu      900

gggugguacu gcgauaaugc aggaagcgug ucguucuuuc cucaggccga gaccuguaag      960

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1020

aaucucugca auguggauau cuuuaacccc aaauaugacu guaagauaau gaccaguaaa     1080

acagauguaa gcuccucugu uauuacuagc cugggugcua ucgugucaug cuacggcaag     1140

accaaaugua cagccaguaa uaagaacagg gggaucauua agaccuucuc caauggaugc     1200

gacuauguca gcaacaaagg cguggacacu gucucugugg guaauacgcu uuacuguguu     1260

aacaagcaag aggggcaguc acuguaugug aaaggagagc cuaucauuaa cuuuuacgau     1320

ccauugguau ucccgaguga cgaauuugau gcaagcauau cccaggucaa ugagaagauc     1380

aaccagucuc ucgcuuucau ucggaaaucg gacgaacugu uacacaaugu gaacgccggc     1440

aagagcacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

ucccucaucg cggucggccu gcuuuuguau ugcaaggccc gcucaacacc cgugacccug     1560

aguaaagauc aacucucugg gauaaacaau aucgcauuca gcaacuga                  1608


<210>  2379
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2379
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1560

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  2380
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2380
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagaa uaaaugcaac gggaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggaccucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuauuugu agcggggucg ccgugugcaa gguucuccac      360

cuggagggag aggugaacaa aaucaagucc gcgcuucuga gcaccaauaa agccgucgug      420

ucucucucca acggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauu      480

gacaaacaac uccugccuau ccugaacaag cagucuuguu ccauuccgaa uaucgaaacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      600

aacgcuggcg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      660

cugaucaacg auaugccuau uaccaacgac caaaagaaac uuauguccaa uaacgugcag      720

aucgugagac agcagucuua cagcauuaug ugcaucauua aggaagaggu ccuggccuau      780

gugguucaac ucccccugua cggggugauc gauacaccuu guuggaaacu gcauacgagc      840

ccccucugca ccacaaauac caaggaagga uccaacaucu gucugacacg gaccgaccgc      900

ggcugguacu gcgauaaugc ugggucuguc uccuucuuuc cucaggccga gacguguaag      960

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1020

aaucucugca augucgauau uuuuaacccc aaauaugacu guaagaucau gaccuccaaa     1080

acagaugugu cuagcuccgu cauuaccagc cugggagcga ucgugucuug cuacggcaag     1140

acaaaaugua cggccuccaa uaagaaccgg gggauuauca agaccuucag caauggaugc     1200

gacuauguuu cuaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuguguu     1260

aacaagcaag aggggcagag ccuguaugug aaaggagagc cuaucauuaa cuuuuacgau     1320

ccccucgucu ucccuuccga cgaauuugau gcuucuauca gccaggugaa ugagaagauu     1380

aaccaguccc uggccuucau ccgcaaaucu gacgaacugc uccacaaugu gaacgcuggc     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucccugaucg ccguggggcu ccugcuguau ugcaaggcca gaagcacacc cgugacccuu     1560

ucuaaagauc aacucuccgg aauuaacaau aucgcuuuca gcaacuga                  1608


<210>  2381
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2381
auggaacuac uaauccuaaa agcaaacgca auuacaacua uacuuaccgc cguaacauuu       60

ugcuucgcau cugggcaaaa cauuaccgaa gaauuuuauc aaucaacaug cucagcaguc      120

uccaaaggau accuuggagc auuaagaacc ggcugguaua ccuccguaau aacaauugaa      180

cuaucuaaua uaaaagaaaa uaaauguaau ggaacugacg caaaaguuaa acuaauaaaa      240

caagaacucg acaaauacaa aaacgccguc acagaccuac aacuacuaau gcaaucaacc      300

cccgcaacag gaucaggauc cgcaaucugc agcggcgucg caguuugcaa aguccuacau      360

uuagaaggag aaguaaacaa aauaaaaucu gcucuccucu cuacaaacaa agcaguagug      420

ucacuuucaa acggaguauc aguucuaaca uucaaaguac uagaccuaaa aaauuacaua      480

gacaaacaac uacuuccaau ucuaaacaaa caauccuguu ccauacccaa cauagaaaca      540

guaauagaau uucaacaaaa aaauaacaga cuccuagaaa uuacaagaga auuuuccguc      600

aaugcaggag uaacaacccc aguaucaacc uacauguuaa cuaacucaga acucuuauca      660

cuaauaaacg acaugccaau cacuaaugac caaaaaaaac ucaugucaaa uaacguacaa      720

auaguccgac aacaaucaua cuccaucaug ugcauuauaa aagaagaagu acuagcauac      780

gucguccaau uaccacuaua cggcgucaua gacacaccau guuggaaacu ccacacauca      840

ccacuaugca cuacaaauac aaaagaaggc uccaacaucu gccuaacaag aacagacaga      900

gguugguauu gcgacaacgc aggaucagua ucauuuuucc cccaagcaga aacauguaaa      960

guacaaucaa auagagucuu cugcgacacc augaacucau uaacacuacc uucagaaguc     1020

aaccuaugca acguagacau cuucaacccu aaauaugacu gcaaaaucau gaccagcaaa     1080

accgacguuu caucuuccgu aauaacauca cuaggcgcaa uagucucaug uuacggcaaa     1140

acaaaaugua cagcaucaaa uaaaaaccgu ggaauaauaa aaacauuuuc uaaugguugu     1200

gacuacguaa gcaauaaagg aguagauaca guaucagucg gcaacaccuu auacugugua     1260

aacaaacaag aaggccaaag uuuauacguc aaaggagaac ccaucaucaa cuucuacgac     1320

ccauuaguau ucccaucaga cgaauuugau gcaagcauuu cacaagucaa cgaaaaaauc     1380

aaucaaucau uagcauucau ccgaaaauca gacgaauuau uacacaacgu aaacgccgga     1440

aaaucaacca cuaauauaau gauaaccaca auaaucaucg uaauaauagu aauacuucuc     1500

ucacuaaucg cagucggacu ccuucuauac ugcaaagcaa gaucuacacc aguaacacua     1560

uccaaagauc aacuaagugg cauaaacaac auagcauuuu cuaacuaa                  1608


<210>  2382
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut2

<400>  2382
auggaacucc ucauccuaaa agccaacgcg aucaccacaa uccugacagc cgucaccuuc       60

ugcuucgccu ccggccaaaa caucaccgaa gaguucuacc aauccacaug cuccgccguc      120

uccaagggcu accugggcgc acuucguaca ggcugguaca ccuccguaau aaccaucgaa      180

cucuccaaca ucaaagaaaa caaaugcaac ggcacagacg caaaagucaa acucaucaag      240

caagaacuug acaaauacaa aaaugcaguc accgaccuuc aacuccucau gcaaucuacc      300

cccgccacag gcuccggcuc cgcuaucugc uccggcgucg ccgucugcaa aguccuccac      360

cucgaaggug aaguaaacaa aauaaaaucc gcccuccucu ccaccaacaa agccgucguc      420

ucccuaucaa acggcgucuc cgugcucacc uucaagguuc ucgaccugaa aaacuacaua      480

gacaaacagc uccuaccaau ccuuaacaaa cagagcugcu ccauuccgaa uaucgaaacg      540

guaaucgaau uucaacagaa aaacaaccgc cuccucgaaa uaacgcgaga guucuccgua      600

aacgcuggcg ucaccacacc cgucagcacc uacaugcuaa cgaacuccga acucuugucg      660

cucaucaacg acaugcccau aaccaacgac caaaagaaac uaauguccaa uaacguacaa      720

aucguacgcc aacaaucuua cuccaucaug ugcaucauaa aagaagaagu acuagcuuac      780

gucguccaac ucccacugua cggagucauc gacacccccu gcuggaaacu ccacaccucu      840

ccccucugca ccaccaacac caaagagggc uccaacauuu gccugacacg caccgaccgc      900

ggcugguacu gcgacaacgc aggcuccguc ucguucuucc cccaagccga aaccugcaaa      960

guccaaucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgaaguc     1020

aaucuaugca acguagacau cuucaacccg aaauaugacu gcaaaauuau gacaucuaaa     1080

accgacgugu ccuccucagu caucacuucc cuaggagcca ucguuuccug uuacggcaag     1140

accaaaugca ccgccagcaa caaaaaccga ggcaucauca aaaccuucuc caacggaugu     1200

gacuaugucu ccaacaaggg cgucgacacc gucagcgucg gcaacacccu cuacugcguc     1260

aacaaacaag aaggccaauc ccucuacguc aaaggagagc ccauaaucaa cuucuacgac     1320

ccccucgucu ucccauccga cgaguucgac gccucaaucu cccaagucaa cgagaaaauc     1380

aaccaauccu uagccuucau ccguaagucc gacgaacucc uucacaacgu caacgccggu     1440

aaaucuacca ccaacaucau gauaacaaca auaauuaucg ucaucaucgu cauccuccuu     1500

ucccucaucg cggucgggcu auugcucuac ugcaaagccc gguccacccc aguaacccuc     1560

ucuaaagacc aacucagcgg aaucaauaac auagccuuca gcaauuaa                  1608


<210>  2383
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2383
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2384
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2384
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2385
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2385
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2386
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2386
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2387
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2387
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2388
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2388
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2389
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2389
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac      120

uuaccgccgu aacauuuugc uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau      180

caacaugcuc agcagucucc aaaggauacc uuggagcauu aagaaccggc ugguauaccu      240

ccguaauaac aauugaacua ucuaauauaa aagaaaauaa auguaaugga acugacgcaa      300

aaguuaaacu aauaaaacaa gaacucgaca aauacaaaaa cgccgucaca gaccuacaac      360

uacuaaugca aucaaccccc gcaacaggau caggauccgc aaucugcagc ggcgucgcag      420

uuugcaaagu ccuacauuua gaaggagaag uaaacaaaau aaaaucugcu cuccucucua      480

caaacaaagc aguaguguca cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag      540

accuaaaaaa uuacauagac aaacaacuac uuccaauucu aaacaaacaa uccuguucca      600

uacccaacau agaaacagua auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua      660

caagagaauu uuccgucaau gcaggaguaa caaccccagu aucaaccuac auguuaacua      720

acucagaacu cuuaucacua auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca      780

ugucaaauaa cguacaaaua guccgacaac aaucauacuc caucaugugc auuauaaaag      840

aagaaguacu agcauacguc guccaauuac cacuauacgg cgucauagac acaccauguu      900

ggaaacucca cacaucacca cuaugcacua caaauacaaa agaaggcucc aacaucugcc      960

uaacaagaac agacagaggu ugguauugcg acaacgcagg aucaguauca uuuuuccccc     1020

aagcagaaac auguaaagua caaucaaaua gagucuucug cgacaccaug aacucauuaa     1080

cacuaccuuc agaagucaac cuaugcaacg uagacaucuu caacccuaaa uaugacugca     1140

aaaucaugac cagcaaaacc gacguuucau cuuccguaau aacaucacua ggcgcaauag     1200

ucucauguua cggcaaaaca aaauguacag caucaaauaa aaaccgugga auaauaaaaa     1260

cauuuucuaa ugguugugac uacguaagca auaaaggagu agauacagua ucagucggca     1320

acaccuuaua cuguguaaac aaacaagaag gccaaaguuu auacgucaaa ggagaaccca     1380

ucaucaacuu cuacgaccca uuaguauucc caucagacga auuugaugca agcauuucac     1440

aagucaacga aaaaaucaau caaucauuag cauucauccg aaaaucagac gaauuauuac     1500

acaacguaaa cgccggaaaa ucaaccacua auauaaugau aaccacaaua aucaucguaa     1560

uaauaguaau acuucucuca cuaaucgcag ucggacuccu ucuauacugc aaagcaagau     1620

cuacaccagu aacacuaucc aaagaucaac uaaguggcau aaacaacaua gcauuuucua     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2390
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2390
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuaaaagc caacgcgauc accacaaucc      120

ugacagccgu caccuucugc uucgccuccg gccaaaacau caccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aagggcuacc ugggcgcacu ucguacaggc ugguacaccu      240

ccguaauaac caucgaacuc uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaagcaa gaacuugaca aauacaaaaa ugcagucacc gaccuucaac      360

uccucaugca aucuaccccc gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggugaag uaaacaaaau aaaauccgcc cuccucucca      480

ccaacaaagc cgucgucucc cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg      540

accugaaaaa cuacauagac aaacagcucc uaccaauccu uaacaaacag agcugcucca      600

uuccgaauau cgaaacggua aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa      660

cgcgagaguu cuccguaaac gcuggcguca ccacacccgu cagcaccuac augcuaacga      720

acuccgaacu cuugucgcuc aucaacgaca ugcccauaac caacgaccaa aagaaacuaa      780

uguccaauaa cguacaaauc guacgccaac aaucuuacuc caucaugugc aucauaaaag      840

aagaaguacu agcuuacguc guccaacucc cacuguacgg agucaucgac acccccugcu      900

ggaaacucca caccucuccc cucugcacca ccaacaccaa agagggcucc aacauuugcc      960

ugacacgcac cgaccgcggc ugguacugcg acaacgcagg cuccgucucg uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaagucaau cuaugcaacg uagacaucuu caacccgaaa uaugacugca     1140

aaauuaugac aucuaaaacc gacguguccu ccucagucau cacuucccua ggagccaucg     1200

uuuccuguua cggcaagacc aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa     1260

ccuucuccaa cggaugugac uaugucucca acaagggcgu cgacaccguc agcgucggca     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu cuacgucaaa ggagagccca     1380

uaaucaacuu cuacgacccc cucgucuucc cauccgacga guucgacgcc ucaaucuccc     1440

aagucaacga gaaaaucaac caauccuuag ccuucauccg uaaguccgac gaacuccuuc     1500

acaacgucaa cgccgguaaa ucuaccacca acaucaugau aacaacaaua auuaucguca     1560

ucaucgucau ccuccuuucc cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu     1620

ccaccccagu aacccucucu aaagaccaac ucagcggaau caauaacaua gccuucagca     1680

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  2391
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2391
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2392
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2392
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2393
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2393
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2394
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2394
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2395
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2395
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2396
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2396
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2397
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2397
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagca      120

aacgcaauua caacuauacu uaccgccgua acauuuugcu ucgcaucugg gcaaaacauu      180

accgaagaau uuuaucaauc aacaugcuca gcagucucca aaggauaccu uggagcauua      240

agaaccggcu gguauaccuc cguaauaaca auugaacuau cuaauauaaa agaaaauaaa      300

uguaauggaa cugacgcaaa aguuaaacua auaaaacaag aacucgacaa auacaaaaac      360

gccgucacag accuacaacu acuaaugcaa ucaacccccg caacaggauc aggauccgca      420

aucugcagcg gcgucgcagu uugcaaaguc cuacauuuag aaggagaagu aaacaaaaua      480

aaaucugcuc uccucucuac aaacaaagca guagugucac uuucaaacgg aguaucaguu      540

cuaacauuca aaguacuaga ccuaaaaaau uacauagaca aacaacuacu uccaauucua      600

aacaaacaau ccuguuccau acccaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagacucc uagaaauuac aagagaauuu uccgucaaug caggaguaac aaccccagua      720

ucaaccuaca uguuaacuaa cucagaacuc uuaucacuaa uaaacgacau gccaaucacu      780

aaugaccaaa aaaaacucau gucaaauaac guacaaauag uccgacaaca aucauacucc      840

aucaugugca uuauaaaaga agaaguacua gcauacgucg uccaauuacc acuauacggc      900

gucauagaca caccauguug gaaacuccac acaucaccac uaugcacuac aaauacaaaa      960

gaaggcucca acaucugccu aacaagaaca gacagagguu gguauugcga caacgcagga     1020

ucaguaucau uuuuccccca agcagaaaca uguaaaguac aaucaaauag agucuucugc     1080

gacaccauga acucauuaac acuaccuuca gaagucaacc uaugcaacgu agacaucuuc     1140

aacccuaaau augacugcaa aaucaugacc agcaaaaccg acguuucauc uuccguaaua     1200

acaucacuag gcgcaauagu cucauguuac ggcaaaacaa aauguacagc aucaaauaaa     1260

aaccguggaa uaauaaaaac auuuucuaau gguugugacu acguaagcaa uaaaggagua     1320

gauacaguau cagucggcaa caccuuauac uguguaaaca aacaagaagg ccaaaguuua     1380

uacgucaaag gagaacccau caucaacuuc uacgacccau uaguauuccc aucagacgaa     1440

uuugaugcaa gcauuucaca agucaacgaa aaaaucaauc aaucauuagc auucauccga     1500

aaaucagacg aauuauuaca caacguaaac gccggaaaau caaccacuaa uauaaugaua     1560

accacaauaa ucaucguaau aauaguaaua cuucucucac uaaucgcagu cggacuccuu     1620

cuauacugca aagcaagauc uacaccagua acacuaucca aagaucaacu aaguggcaua     1680

aacaacauag cauuuucuaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2398
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2398
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuaaaagcc      120

aacgcgauca ccacaauccu gacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca agggcuaccu gggcgcacuu      240

cguacaggcu gguacaccuc cguaauaacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaagcaag aacuugacaa auacaaaaau      360

gcagucaccg accuucaacu ccucaugcaa ucuacccccg ccacaggcuc cggcuccgcu      420

aucugcuccg gcgucgccgu cugcaaaguc cuccaccucg aaggugaagu aaacaaaaua      480

aaauccgccc uccucuccac caacaaagcc gucgucuccc uaucaaacgg cgucuccgug      540

cucaccuuca agguucucga ccugaaaaac uacauagaca aacagcuccu accaauccuu      600

aacaaacaga gcugcuccau uccgaauauc gaaacgguaa ucgaauuuca acagaaaaac      660

aaccgccucc ucgaaauaac gcgagaguuc uccguaaacg cuggcgucac cacacccguc      720

agcaccuaca ugcuaacgaa cuccgaacuc uugucgcuca ucaacgacau gcccauaacc      780

aacgaccaaa agaaacuaau guccaauaac guacaaaucg uacgccaaca aucuuacucc      840

aucaugugca ucauaaaaga agaaguacua gcuuacgucg uccaacuccc acuguacgga      900

gucaucgaca cccccugcug gaaacuccac accucucccc ucugcaccac caacaccaaa      960

gagggcucca acauuugccu gacacgcacc gaccgcggcu gguacugcga caacgcaggc     1020

uccgucucgu ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaagucaauc uaugcaacgu agacaucuuc     1140

aacccgaaau augacugcaa aauuaugaca ucuaaaaccg acguguccuc cucagucauc     1200

acuucccuag gagccaucgu uuccuguuac ggcaagacca aaugcaccgc cagcaacaaa     1260

aaccgaggca ucaucaaaac cuucuccaac ggaugugacu augucuccaa caagggcguc     1320

gacaccguca gcgucggcaa cacccucuac ugcgucaaca aacaagaagg ccaaucccuc     1380

uacgucaaag gagagcccau aaucaacuuc uacgaccccc ucgucuuccc auccgacgag     1440

uucgacgccu caaucuccca agucaacgag aaaaucaacc aauccuuagc cuucauccgu     1500

aaguccgacg aacuccuuca caacgucaac gccgguaaau cuaccaccaa caucaugaua     1560

acaacaauaa uuaucgucau caucgucauc cuccuuuccc ucaucgcggu cgggcuauug     1620

cucuacugca aagcccgguc caccccagua acccucucua aagaccaacu cagcggaauc     1680

aauaacauag ccuucagcaa uuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  2399
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2399
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2400
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2400
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2401
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2401
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2402
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2402
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2403
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2403
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2404
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2404
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2405
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2405
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagcaaa cgcaauuaca acuauacuua ccgccguaac auuuugcuuc      240

gcaucugggc aaaacauuac cgaagaauuu uaucaaucaa caugcucagc agucuccaaa      300

ggauaccuug gagcauuaag aaccggcugg uauaccuccg uaauaacaau ugaacuaucu      360

aauauaaaag aaaauaaaug uaauggaacu gacgcaaaag uuaaacuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cgucacagac cuacaacuac uaaugcaauc aacccccgca      480

acaggaucag gauccgcaau cugcagcggc gucgcaguuu gcaaaguccu acauuuagaa      540

ggagaaguaa acaaaauaaa aucugcucuc cucucuacaa acaaagcagu agugucacuu      600

ucaaacggag uaucaguucu aacauucaaa guacuagacc uaaaaaauua cauagacaaa      660

caacuacuuc caauucuaaa caaacaaucc uguuccauac ccaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagacuccua gaaauuacaa gagaauuuuc cgucaaugca      780

ggaguaacaa ccccaguauc aaccuacaug uuaacuaacu cagaacucuu aucacuaaua      840

aacgacaugc caaucacuaa ugaccaaaaa aaacucaugu caaauaacgu acaaauaguc      900

cgacaacaau cauacuccau caugugcauu auaaaagaag aaguacuagc auacgucguc      960

caauuaccac uauacggcgu cauagacaca ccauguugga aacuccacac aucaccacua     1020

ugcacuacaa auacaaaaga aggcuccaac aucugccuaa caagaacaga cagagguugg     1080

uauugcgaca acgcaggauc aguaucauuu uucccccaag cagaaacaug uaaaguacaa     1140

ucaaauagag ucuucugcga caccaugaac ucauuaacac uaccuucaga agucaaccua     1200

ugcaacguag acaucuucaa cccuaaauau gacugcaaaa ucaugaccag caaaaccgac     1260

guuucaucuu ccguaauaac aucacuaggc gcaauagucu cauguuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa ccguggaaua auaaaaacau uuucuaaugg uugugacuac     1380

guaagcaaua aaggaguaga uacaguauca gucggcaaca ccuuauacug uguaaacaaa     1440

caagaaggcc aaaguuuaua cgucaaagga gaacccauca ucaacuucua cgacccauua     1500

guauucccau cagacgaauu ugaugcaagc auuucacaag ucaacgaaaa aaucaaucaa     1560

ucauuagcau ucauccgaaa aucagacgaa uuauuacaca acguaaacgc cggaaaauca     1620

accacuaaua uaaugauaac cacaauaauc aucguaauaa uaguaauacu ucucucacua     1680

aucgcagucg gacuccuucu auacugcaaa gcaagaucua caccaguaac acuauccaaa     1740

gaucaacuaa guggcauaaa caacauagca uuuucuaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2406
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2406
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uaaaagccaa cgcgaucacc acaauccuga cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaagaguuc uaccaaucca caugcuccgc cgucuccaag      300

ggcuaccugg gcgcacuucg uacaggcugg uacaccuccg uaauaaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caagcaagaa      420

cuugacaaau acaaaaaugc agucaccgac cuucaacucc ucaugcaauc uacccccgcc      480

acaggcuccg gcuccgcuau cugcuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggugaaguaa acaaaauaaa auccgcccuc cucuccacca acaaagccgu cgucucccua      600

ucaaacggcg ucuccgugcu caccuucaag guucucgacc ugaaaaacua cauagacaaa      660

cagcuccuac caauccuuaa caaacagagc ugcuccauuc cgaauaucga aacgguaauc      720

gaauuucaac agaaaaacaa ccgccuccuc gaaauaacgc gagaguucuc cguaaacgcu      780

ggcgucacca cacccgucag caccuacaug cuaacgaacu ccgaacucuu gucgcucauc      840

aacgacaugc ccauaaccaa cgaccaaaag aaacuaaugu ccaauaacgu acaaaucgua      900

cgccaacaau cuuacuccau caugugcauc auaaaagaag aaguacuagc uuacgucguc      960

caacucccac uguacggagu caucgacacc cccugcugga aacuccacac cucuccccuc     1020

ugcaccacca acaccaaaga gggcuccaac auuugccuga cacgcaccga ccgcggcugg     1080

uacugcgaca acgcaggcuc cgucucguuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga agucaaucua     1200

ugcaacguag acaucuucaa cccgaaauau gacugcaaaa uuaugacauc uaaaaccgac     1260

guguccuccu cagucaucac uucccuagga gccaucguuu ccuguuacgg caagaccaaa     1320

ugcaccgcca gcaacaaaaa ccgaggcauc aucaaaaccu ucuccaacgg augugacuau     1380

gucuccaaca agggcgucga caccgucagc gucggcaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccucua cgucaaagga gagcccauaa ucaacuucua cgacccccuc     1500

gucuucccau ccgacgaguu cgacgccuca aucucccaag ucaacgagaa aaucaaccaa     1560

uccuuagccu ucauccguaa guccgacgaa cuccuucaca acgucaacgc cgguaaaucu     1620

accaccaaca ucaugauaac aacaauaauu aucgucauca ucgucauccu ccuuucccuc     1680

aucgcggucg ggcuauugcu cuacugcaaa gcccggucca ccccaguaac ccucucuaaa     1740

gaccaacuca gcggaaucaa uaacauagcc uucagcaauu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  2407
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2407
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2408
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2408
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2409
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2409
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2410
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2410
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2411
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2411
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2412
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2412
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2413
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2413
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagcaaac gcaauuacaa cuauacuuac cgccguaaca      180

uuuugcuucg caucugggca aaacauuacc gaagaauuuu aucaaucaac augcucagca      240

gucuccaaag gauaccuugg agcauuaaga accggcuggu auaccuccgu aauaacaauu      300

gaacuaucua auauaaaaga aaauaaaugu aauggaacug acgcaaaagu uaaacuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagacc uacaacuacu aaugcaauca      420

acccccgcaa caggaucagg auccgcaauc ugcagcggcg ucgcaguuug caaaguccua      480

cauuuagaag gagaaguaaa caaaauaaaa ucugcucucc ucucuacaaa caaagcagua      540

gugucacuuu caaacggagu aucaguucua acauucaaag uacuagaccu aaaaaauuac      600

auagacaaac aacuacuucc aauucuaaac aaacaauccu guuccauacc caacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agacuccuag aaauuacaag agaauuuucc      720

gucaaugcag gaguaacaac cccaguauca accuacaugu uaacuaacuc agaacucuua      780

ucacuaauaa acgacaugcc aaucacuaau gaccaaaaaa aacucauguc aaauaacgua      840

caaauagucc gacaacaauc auacuccauc augugcauua uaaaagaaga aguacuagca      900

uacgucgucc aauuaccacu auacggcguc auagacacac cauguuggaa acuccacaca      960

ucaccacuau gcacuacaaa uacaaaagaa ggcuccaaca ucugccuaac aagaacagac     1020

agagguuggu auugcgacaa cgcaggauca guaucauuuu ucccccaagc agaaacaugu     1080

aaaguacaau caaauagagu cuucugcgac accaugaacu cauuaacacu accuucagaa     1140

gucaaccuau gcaacguaga caucuucaac ccuaaauaug acugcaaaau caugaccagc     1200

aaaaccgacg uuucaucuuc cguaauaaca ucacuaggcg caauagucuc auguuacggc     1260

aaaacaaaau guacagcauc aaauaaaaac cguggaauaa uaaaaacauu uucuaauggu     1320

ugugacuacg uaagcaauaa aggaguagau acaguaucag ucggcaacac cuuauacugu     1380

guaaacaaac aagaaggcca aaguuuauac gucaaaggag aacccaucau caacuucuac     1440

gacccauuag uauucccauc agacgaauuu gaugcaagca uuucacaagu caacgaaaaa     1500

aucaaucaau cauuagcauu cauccgaaaa ucagacgaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa ccacuaauau aaugauaacc acaauaauca ucguaauaau aguaauacuu     1620

cucucacuaa ucgcagucgg acuccuucua uacugcaaag caagaucuac accaguaaca     1680

cuauccaaag aucaacuaag uggcauaaac aacauagcau uuucuaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2414
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2414
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu aaaagccaac gcgaucacca caauccugac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaagaguucu accaauccac augcuccgcc      240

gucuccaagg gcuaccuggg cgcacuucgu acaggcuggu acaccuccgu aauaaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aagcaagaac uugacaaaua caaaaaugca gucaccgacc uucaacuccu caugcaaucu      420

acccccgcca caggcuccgg cuccgcuauc ugcuccggcg ucgccgucug caaaguccuc      480

caccucgaag gugaaguaaa caaaauaaaa uccgcccucc ucuccaccaa caaagccguc      540

gucucccuau caaacggcgu cuccgugcuc accuucaagg uucucgaccu gaaaaacuac      600

auagacaaac agcuccuacc aauccuuaac aaacagagcu gcuccauucc gaauaucgaa      660

acgguaaucg aauuucaaca gaaaaacaac cgccuccucg aaauaacgcg agaguucucc      720

guaaacgcug gcgucaccac acccgucagc accuacaugc uaacgaacuc cgaacucuug      780

ucgcucauca acgacaugcc cauaaccaac gaccaaaaga aacuaauguc caauaacgua      840

caaaucguac gccaacaauc uuacuccauc augugcauca uaaaagaaga aguacuagcu      900

uacgucgucc aacucccacu guacggaguc aucgacaccc ccugcuggaa acuccacacc      960

ucuccccucu gcaccaccaa caccaaagag ggcuccaaca uuugccugac acgcaccgac     1020

cgcggcuggu acugcgacaa cgcaggcucc gucucguucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgaa     1140

gucaaucuau gcaacguaga caucuucaac ccgaaauaug acugcaaaau uaugacaucu     1200

aaaaccgacg uguccuccuc agucaucacu ucccuaggag ccaucguuuc cuguuacggc     1260

aagaccaaau gcaccgccag caacaaaaac cgaggcauca ucaaaaccuu cuccaacgga     1320

ugugacuaug ucuccaacaa gggcgucgac accgucagcg ucggcaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccucuac gucaaaggag agcccauaau caacuucuac     1440

gacccccucg ucuucccauc cgacgaguuc gacgccucaa ucucccaagu caacgagaaa     1500

aucaaccaau ccuuagccuu cauccguaag uccgacgaac uccuucacaa cgucaacgcc     1560

gguaaaucua ccaccaacau caugauaaca acaauaauua ucgucaucau cgucauccuc     1620

cuuucccuca ucgcggucgg gcuauugcuc uacugcaaag cccgguccac cccaguaacc     1680

cucucuaaag accaacucag cggaaucaau aacauagccu ucagcaauua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  2415
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2415
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2416
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2416
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2417
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2417
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2418
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2418
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2419
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2419
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2420
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2420
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2421
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2421
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gcaaacgcaa uuacaacuau acuuaccgcc      120

guaacauuuu gcuucgcauc ugggcaaaac auuaccgaag aauuuuauca aucaacaugc      180

ucagcagucu ccaaaggaua ccuuggagca uuaagaaccg gcugguauac cuccguaaua      240

acaauugaac uaucuaauau aaaagaaaau aaauguaaug gaacugacgc aaaaguuaaa      300

cuaauaaaac aagaacucga caaauacaaa aacgccguca cagaccuaca acuacuaaug      360

caaucaaccc ccgcaacagg aucaggaucc gcaaucugca gcggcgucgc aguuugcaaa      420

guccuacauu uagaaggaga aguaaacaaa auaaaaucug cucuccucuc uacaaacaaa      480

gcaguagugu cacuuucaaa cggaguauca guucuaacau ucaaaguacu agaccuaaaa      540

aauuacauag acaaacaacu acuuccaauu cuaaacaaac aauccuguuc cauacccaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagac uccuagaaau uacaagagaa      660

uuuuccguca augcaggagu aacaacccca guaucaaccu acauguuaac uaacucagaa      720

cucuuaucac uaauaaacga caugccaauc acuaaugacc aaaaaaaacu caugucaaau      780

aacguacaaa uaguccgaca acaaucauac uccaucaugu gcauuauaaa agaagaagua      840

cuagcauacg ucguccaauu accacuauac ggcgucauag acacaccaug uuggaaacuc      900

cacacaucac cacuaugcac uacaaauaca aaagaaggcu ccaacaucug ccuaacaaga      960

acagacagag guugguauug cgacaacgca ggaucaguau cauuuuuccc ccaagcagaa     1020

acauguaaag uacaaucaaa uagagucuuc ugcgacacca ugaacucauu aacacuaccu     1080

ucagaaguca accuaugcaa cguagacauc uucaacccua aauaugacug caaaaucaug     1140

accagcaaaa ccgacguuuc aucuuccgua auaacaucac uaggcgcaau agucucaugu     1200

uacggcaaaa caaaauguac agcaucaaau aaaaaccgug gaauaauaaa aacauuuucu     1260

aaugguugug acuacguaag caauaaagga guagauacag uaucagucgg caacaccuua     1320

uacuguguaa acaaacaaga aggccaaagu uuauacguca aaggagaacc caucaucaac     1380

uucuacgacc cauuaguauu cccaucagac gaauuugaug caagcauuuc acaagucaac     1440

gaaaaaauca aucaaucauu agcauucauc cgaaaaucag acgaauuauu acacaacgua     1500

aacgccggaa aaucaaccac uaauauaaug auaaccacaa uaaucaucgu aauaauagua     1560

auacuucucu cacuaaucgc agucggacuc cuucuauacu gcaaagcaag aucuacacca     1620

guaacacuau ccaaagauca acuaaguggc auaaacaaca uagcauuuuc uaacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2422
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2422
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuaaaa gccaacgcga ucaccacaau ccugacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaagggcua ccugggcgca cuucguacag gcugguacac cuccguaaua      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaagc aagaacuuga caaauacaaa aaugcaguca ccgaccuuca acuccucaug      360

caaucuaccc ccgccacagg cuccggcucc gcuaucugcu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaagguga aguaaacaaa auaaaauccg cccuccucuc caccaacaaa      480

gccgucgucu cccuaucaaa cggcgucucc gugcucaccu ucaagguucu cgaccugaaa      540

aacuacauag acaaacagcu ccuaccaauc cuuaacaaac agagcugcuc cauuccgaau      600

aucgaaacgg uaaucgaauu ucaacagaaa aacaaccgcc uccucgaaau aacgcgagag      660

uucuccguaa acgcuggcgu caccacaccc gucagcaccu acaugcuaac gaacuccgaa      720

cucuugucgc ucaucaacga caugcccaua accaacgacc aaaagaaacu aauguccaau      780

aacguacaaa ucguacgcca acaaucuuac uccaucaugu gcaucauaaa agaagaagua      840

cuagcuuacg ucguccaacu cccacuguac ggagucaucg acacccccug cuggaaacuc      900

cacaccucuc cccucugcac caccaacacc aaagagggcu ccaacauuug ccugacacgc      960

accgaccgcg gcugguacug cgacaacgca ggcuccgucu cguucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgaaguca aucuaugcaa cguagacauc uucaacccga aauaugacug caaaauuaug     1140

acaucuaaaa ccgacguguc cuccucaguc aucacuuccc uaggagccau cguuuccugu     1200

uacggcaaga ccaaaugcac cgccagcaac aaaaaccgag gcaucaucaa aaccuucucc     1260

aacggaugug acuaugucuc caacaagggc gucgacaccg ucagcgucgg caacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cucuacguca aaggagagcc cauaaucaac     1380

uucuacgacc cccucgucuu cccauccgac gaguucgacg ccucaaucuc ccaagucaac     1440

gagaaaauca accaauccuu agccuucauc cguaaguccg acgaacuccu ucacaacguc     1500

aacgccggua aaucuaccac caacaucaug auaacaacaa uaauuaucgu caucaucguc     1560

auccuccuuu cccucaucgc ggucgggcua uugcucuacu gcaaagcccg guccacccca     1620

guaacccucu cuaaagacca acucagcgga aucaauaaca uagccuucag caauuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  2423
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2423
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1800

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2424
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2424
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      660

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1500

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1560

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1800

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2425
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2425
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1800

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2426
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2426
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      600

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      660

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      720

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      840

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      900

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      960

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua     1020

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc     1080

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg     1140

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1200

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1260

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1320

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1380

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1440

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1500

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1560

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1620

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1680

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1740

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1800

aaagaucaac ucucugggau aaacaauauc gcauucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2427
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2427
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1800

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2428
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2428
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      600

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      660

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      720

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      840

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      900

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      960

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug     1020

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc     1080

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc     1140

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1200

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1260

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1320

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1380

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1440

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1500

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1560

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1620

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1740

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1800

aaagaucaac ucuccggaau uaacaauauc gcuuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2429
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2429
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac uuaccgccgu aacauuuugc      300

uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau caacaugcuc agcagucucc      360

aaaggauacc uuggagcauu aagaaccggc ugguauaccu ccguaauaac aauugaacua      420

ucuaauauaa aagaaaauaa auguaaugga acugacgcaa aaguuaaacu aauaaaacaa      480

gaacucgaca aauacaaaaa cgccgucaca gaccuacaac uacuaaugca aucaaccccc      540

gcaacaggau caggauccgc aaucugcagc ggcgucgcag uuugcaaagu ccuacauuua      600

gaaggagaag uaaacaaaau aaaaucugcu cuccucucua caaacaaagc aguaguguca      660

cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag accuaaaaaa uuacauagac      720

aaacaacuac uuccaauucu aaacaaacaa uccuguucca uacccaacau agaaacagua      780

auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua caagagaauu uuccgucaau      840

gcaggaguaa caaccccagu aucaaccuac auguuaacua acucagaacu cuuaucacua      900

auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca ugucaaauaa cguacaaaua      960

guccgacaac aaucauacuc caucaugugc auuauaaaag aagaaguacu agcauacguc     1020

guccaauuac cacuauacgg cgucauagac acaccauguu ggaaacucca cacaucacca     1080

cuaugcacua caaauacaaa agaaggcucc aacaucugcc uaacaagaac agacagaggu     1140

ugguauugcg acaacgcagg aucaguauca uuuuuccccc aagcagaaac auguaaagua     1200

caaucaaaua gagucuucug cgacaccaug aacucauuaa cacuaccuuc agaagucaac     1260

cuaugcaacg uagacaucuu caacccuaaa uaugacugca aaaucaugac cagcaaaacc     1320

gacguuucau cuuccguaau aacaucacua ggcgcaauag ucucauguua cggcaaaaca     1380

aaauguacag caucaaauaa aaaccgugga auaauaaaaa cauuuucuaa ugguugugac     1440

uacguaagca auaaaggagu agauacagua ucagucggca acaccuuaua cuguguaaac     1500

aaacaagaag gccaaaguuu auacgucaaa ggagaaccca ucaucaacuu cuacgaccca     1560

uuaguauucc caucagacga auuugaugca agcauuucac aagucaacga aaaaaucaau     1620

caaucauuag cauucauccg aaaaucagac gaauuauuac acaacguaaa cgccggaaaa     1680

ucaaccacua auauaaugau aaccacaaua aucaucguaa uaauaguaau acuucucuca     1740

cuaaucgcag ucggacuccu ucuauacugc aaagcaagau cuacaccagu aacacuaucc     1800

aaagaucaac uaaguggcau aaacaacaua gcauuuucua acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2430
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2430
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccuaaaagc caacgcgauc accacaaucc ugacagccgu caccuucugc      300

uucgccuccg gccaaaacau caccgaagag uucuaccaau ccacaugcuc cgccgucucc      360

aagggcuacc ugggcgcacu ucguacaggc ugguacaccu ccguaauaac caucgaacuc      420

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaagcaa      480

gaacuugaca aauacaaaaa ugcagucacc gaccuucaac uccucaugca aucuaccccc      540

gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg ucugcaaagu ccuccaccuc      600

gaaggugaag uaaacaaaau aaaauccgcc cuccucucca ccaacaaagc cgucgucucc      660

cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg accugaaaaa cuacauagac      720

aaacagcucc uaccaauccu uaacaaacag agcugcucca uuccgaauau cgaaacggua      780

aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa cgcgagaguu cuccguaaac      840

gcuggcguca ccacacccgu cagcaccuac augcuaacga acuccgaacu cuugucgcuc      900

aucaacgaca ugcccauaac caacgaccaa aagaaacuaa uguccaauaa cguacaaauc      960

guacgccaac aaucuuacuc caucaugugc aucauaaaag aagaaguacu agcuuacguc     1020

guccaacucc cacuguacgg agucaucgac acccccugcu ggaaacucca caccucuccc     1080

cucugcacca ccaacaccaa agagggcucc aacauuugcc ugacacgcac cgaccgcggc     1140

ugguacugcg acaacgcagg cuccgucucg uucuuccccc aagccgaaac cugcaaaguc     1200

caauccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaagucaau     1260

cuaugcaacg uagacaucuu caacccgaaa uaugacugca aaauuaugac aucuaaaacc     1320

gacguguccu ccucagucau cacuucccua ggagccaucg uuuccuguua cggcaagacc     1380

aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa ccuucuccaa cggaugugac     1440

uaugucucca acaagggcgu cgacaccguc agcgucggca acacccucua cugcgucaac     1500

aaacaagaag gccaaucccu cuacgucaaa ggagagccca uaaucaacuu cuacgacccc     1560

cucgucuucc cauccgacga guucgacgcc ucaaucuccc aagucaacga gaaaaucaac     1620

caauccuuag ccuucauccg uaaguccgac gaacuccuuc acaacgucaa cgccgguaaa     1680

ucuaccacca acaucaugau aacaacaaua auuaucguca ucaucgucau ccuccuuucc     1740

cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu ccaccccagu aacccucucu     1800

aaagaccaac ucagcggaau caauaacaua gccuucagca auuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2431
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2431
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2432
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2432
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1620

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2433
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2433
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2434
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2434
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      720

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg      960

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1140

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1440

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1620

aaagaucaac ucucugggau aaacaauauc gcauucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2435
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2435
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2436
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2436
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      720

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc      960

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1440

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1620

aaagaucaac ucuccggaau uaacaauauc gcuuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2437
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2437
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac uuaccgccgu aacauuuugc      120

uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau caacaugcuc agcagucucc      180

aaaggauacc uuggagcauu aagaaccggc ugguauaccu ccguaauaac aauugaacua      240

ucuaauauaa aagaaaauaa auguaaugga acugacgcaa aaguuaaacu aauaaaacaa      300

gaacucgaca aauacaaaaa cgccgucaca gaccuacaac uacuaaugca aucaaccccc      360

gcaacaggau caggauccgc aaucugcagc ggcgucgcag uuugcaaagu ccuacauuua      420

gaaggagaag uaaacaaaau aaaaucugcu cuccucucua caaacaaagc aguaguguca      480

cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag accuaaaaaa uuacauagac      540

aaacaacuac uuccaauucu aaacaaacaa uccuguucca uacccaacau agaaacagua      600

auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua caagagaauu uuccgucaau      660

gcaggaguaa caaccccagu aucaaccuac auguuaacua acucagaacu cuuaucacua      720

auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca ugucaaauaa cguacaaaua      780

guccgacaac aaucauacuc caucaugugc auuauaaaag aagaaguacu agcauacguc      840

guccaauuac cacuauacgg cgucauagac acaccauguu ggaaacucca cacaucacca      900

cuaugcacua caaauacaaa agaaggcucc aacaucugcc uaacaagaac agacagaggu      960

ugguauugcg acaacgcagg aucaguauca uuuuuccccc aagcagaaac auguaaagua     1020

caaucaaaua gagucuucug cgacaccaug aacucauuaa cacuaccuuc agaagucaac     1080

cuaugcaacg uagacaucuu caacccuaaa uaugacugca aaaucaugac cagcaaaacc     1140

gacguuucau cuuccguaau aacaucacua ggcgcaauag ucucauguua cggcaaaaca     1200

aaauguacag caucaaauaa aaaccgugga auaauaaaaa cauuuucuaa ugguugugac     1260

uacguaagca auaaaggagu agauacagua ucagucggca acaccuuaua cuguguaaac     1320

aaacaagaag gccaaaguuu auacgucaaa ggagaaccca ucaucaacuu cuacgaccca     1380

uuaguauucc caucagacga auuugaugca agcauuucac aagucaacga aaaaaucaau     1440

caaucauuag cauucauccg aaaaucagac gaauuauuac acaacguaaa cgccggaaaa     1500

ucaaccacua auauaaugau aaccacaaua aucaucguaa uaauaguaau acuucucuca     1560

cuaaucgcag ucggacuccu ucuauacugc aaagcaagau cuacaccagu aacacuaucc     1620

aaagaucaac uaaguggcau aaacaacaua gcauuuucua acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2438
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2438
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccuaaaagc caacgcgauc accacaaucc ugacagccgu caccuucugc      120

uucgccuccg gccaaaacau caccgaagag uucuaccaau ccacaugcuc cgccgucucc      180

aagggcuacc ugggcgcacu ucguacaggc ugguacaccu ccguaauaac caucgaacuc      240

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaagcaa      300

gaacuugaca aauacaaaaa ugcagucacc gaccuucaac uccucaugca aucuaccccc      360

gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg ucugcaaagu ccuccaccuc      420

gaaggugaag uaaacaaaau aaaauccgcc cuccucucca ccaacaaagc cgucgucucc      480

cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg accugaaaaa cuacauagac      540

aaacagcucc uaccaauccu uaacaaacag agcugcucca uuccgaauau cgaaacggua      600

aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa cgcgagaguu cuccguaaac      660

gcuggcguca ccacacccgu cagcaccuac augcuaacga acuccgaacu cuugucgcuc      720

aucaacgaca ugcccauaac caacgaccaa aagaaacuaa uguccaauaa cguacaaauc      780

guacgccaac aaucuuacuc caucaugugc aucauaaaag aagaaguacu agcuuacguc      840

guccaacucc cacuguacgg agucaucgac acccccugcu ggaaacucca caccucuccc      900

cucugcacca ccaacaccaa agagggcucc aacauuugcc ugacacgcac cgaccgcggc      960

ugguacugcg acaacgcagg cuccgucucg uucuuccccc aagccgaaac cugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaagucaau     1080

cuaugcaacg uagacaucuu caacccgaaa uaugacugca aaauuaugac aucuaaaacc     1140

gacguguccu ccucagucau cacuucccua ggagccaucg uuuccuguua cggcaagacc     1200

aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa ccuucuccaa cggaugugac     1260

uaugucucca acaagggcgu cgacaccguc agcgucggca acacccucua cugcgucaac     1320

aaacaagaag gccaaucccu cuacgucaaa ggagagccca uaaucaacuu cuacgacccc     1380

cucgucuucc cauccgacga guucgacgcc ucaaucuccc aagucaacga gaaaaucaac     1440

caauccuuag ccuucauccg uaaguccgac gaacuccuuc acaacgucaa cgccgguaaa     1500

ucuaccacca acaucaugau aacaacaaua auuaucguca ucaucgucau ccuccuuucc     1560

cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu ccaccccagu aacccucucu     1620

aaagaccaac ucagcggaau caauaacaua gccuucagca auuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  2439
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2439
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2440
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2440
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2441
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2441
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2442
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2442
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2443
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2443
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2444
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2444
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2445
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2445
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac      120

uuaccgccgu aacauuuugc uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau      180

caacaugcuc agcagucucc aaaggauacc uuggagcauu aagaaccggc ugguauaccu      240

ccguaauaac aauugaacua ucuaauauaa aagaaaauaa auguaaugga acugacgcaa      300

aaguuaaacu aauaaaacaa gaacucgaca aauacaaaaa cgccgucaca gaccuacaac      360

uacuaaugca aucaaccccc gcaacaggau caggauccgc aaucugcagc ggcgucgcag      420

uuugcaaagu ccuacauuua gaaggagaag uaaacaaaau aaaaucugcu cuccucucua      480

caaacaaagc aguaguguca cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag      540

accuaaaaaa uuacauagac aaacaacuac uuccaauucu aaacaaacaa uccuguucca      600

uacccaacau agaaacagua auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua      660

caagagaauu uuccgucaau gcaggaguaa caaccccagu aucaaccuac auguuaacua      720

acucagaacu cuuaucacua auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca      780

ugucaaauaa cguacaaaua guccgacaac aaucauacuc caucaugugc auuauaaaag      840

aagaaguacu agcauacguc guccaauuac cacuauacgg cgucauagac acaccauguu      900

ggaaacucca cacaucacca cuaugcacua caaauacaaa agaaggcucc aacaucugcc      960

uaacaagaac agacagaggu ugguauugcg acaacgcagg aucaguauca uuuuuccccc     1020

aagcagaaac auguaaagua caaucaaaua gagucuucug cgacaccaug aacucauuaa     1080

cacuaccuuc agaagucaac cuaugcaacg uagacaucuu caacccuaaa uaugacugca     1140

aaaucaugac cagcaaaacc gacguuucau cuuccguaau aacaucacua ggcgcaauag     1200

ucucauguua cggcaaaaca aaauguacag caucaaauaa aaaccgugga auaauaaaaa     1260

cauuuucuaa ugguugugac uacguaagca auaaaggagu agauacagua ucagucggca     1320

acaccuuaua cuguguaaac aaacaagaag gccaaaguuu auacgucaaa ggagaaccca     1380

ucaucaacuu cuacgaccca uuaguauucc caucagacga auuugaugca agcauuucac     1440

aagucaacga aaaaaucaau caaucauuag cauucauccg aaaaucagac gaauuauuac     1500

acaacguaaa cgccggaaaa ucaaccacua auauaaugau aaccacaaua aucaucguaa     1560

uaauaguaau acuucucuca cuaaucgcag ucggacuccu ucuauacugc aaagcaagau     1620

cuacaccagu aacacuaucc aaagaucaac uaaguggcau aaacaacaua gcauuuucua     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2446
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2446
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuaaaagc caacgcgauc accacaaucc      120

ugacagccgu caccuucugc uucgccuccg gccaaaacau caccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aagggcuacc ugggcgcacu ucguacaggc ugguacaccu      240

ccguaauaac caucgaacuc uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaagcaa gaacuugaca aauacaaaaa ugcagucacc gaccuucaac      360

uccucaugca aucuaccccc gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggugaag uaaacaaaau aaaauccgcc cuccucucca      480

ccaacaaagc cgucgucucc cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg      540

accugaaaaa cuacauagac aaacagcucc uaccaauccu uaacaaacag agcugcucca      600

uuccgaauau cgaaacggua aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa      660

cgcgagaguu cuccguaaac gcuggcguca ccacacccgu cagcaccuac augcuaacga      720

acuccgaacu cuugucgcuc aucaacgaca ugcccauaac caacgaccaa aagaaacuaa      780

uguccaauaa cguacaaauc guacgccaac aaucuuacuc caucaugugc aucauaaaag      840

aagaaguacu agcuuacguc guccaacucc cacuguacgg agucaucgac acccccugcu      900

ggaaacucca caccucuccc cucugcacca ccaacaccaa agagggcucc aacauuugcc      960

ugacacgcac cgaccgcggc ugguacugcg acaacgcagg cuccgucucg uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaagucaau cuaugcaacg uagacaucuu caacccgaaa uaugacugca     1140

aaauuaugac aucuaaaacc gacguguccu ccucagucau cacuucccua ggagccaucg     1200

uuuccuguua cggcaagacc aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa     1260

ccuucuccaa cggaugugac uaugucucca acaagggcgu cgacaccguc agcgucggca     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu cuacgucaaa ggagagccca     1380

uaaucaacuu cuacgacccc cucgucuucc cauccgacga guucgacgcc ucaaucuccc     1440

aagucaacga gaaaaucaac caauccuuag ccuucauccg uaaguccgac gaacuccuuc     1500

acaacgucaa cgccgguaaa ucuaccacca acaucaugau aacaacaaua auuaucguca     1560

ucaucgucau ccuccuuucc cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu     1620

ccaccccagu aacccucucu aaagaccaac ucagcggaau caauaacaua gccuucagca     1680

auuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2447
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2447
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2448
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2448
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2449
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2449
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2450
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2450
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2451
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2451
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2452
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2452
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2453
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2453
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac      120

uuaccgccgu aacauuuugc uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau      180

caacaugcuc agcagucucc aaaggauacc uuggagcauu aagaaccggc ugguauaccu      240

ccguaauaac aauugaacua ucuaauauaa aagaaaauaa auguaaugga acugacgcaa      300

aaguuaaacu aauaaaacaa gaacucgaca aauacaaaaa cgccgucaca gaccuacaac      360

uacuaaugca aucaaccccc gcaacaggau caggauccgc aaucugcagc ggcgucgcag      420

uuugcaaagu ccuacauuua gaaggagaag uaaacaaaau aaaaucugcu cuccucucua      480

caaacaaagc aguaguguca cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag      540

accuaaaaaa uuacauagac aaacaacuac uuccaauucu aaacaaacaa uccuguucca      600

uacccaacau agaaacagua auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua      660

caagagaauu uuccgucaau gcaggaguaa caaccccagu aucaaccuac auguuaacua      720

acucagaacu cuuaucacua auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca      780

ugucaaauaa cguacaaaua guccgacaac aaucauacuc caucaugugc auuauaaaag      840

aagaaguacu agcauacguc guccaauuac cacuauacgg cgucauagac acaccauguu      900

ggaaacucca cacaucacca cuaugcacua caaauacaaa agaaggcucc aacaucugcc      960

uaacaagaac agacagaggu ugguauugcg acaacgcagg aucaguauca uuuuuccccc     1020

aagcagaaac auguaaagua caaucaaaua gagucuucug cgacaccaug aacucauuaa     1080

cacuaccuuc agaagucaac cuaugcaacg uagacaucuu caacccuaaa uaugacugca     1140

aaaucaugac cagcaaaacc gacguuucau cuuccguaau aacaucacua ggcgcaauag     1200

ucucauguua cggcaaaaca aaauguacag caucaaauaa aaaccgugga auaauaaaaa     1260

cauuuucuaa ugguugugac uacguaagca auaaaggagu agauacagua ucagucggca     1320

acaccuuaua cuguguaaac aaacaagaag gccaaaguuu auacgucaaa ggagaaccca     1380

ucaucaacuu cuacgaccca uuaguauucc caucagacga auuugaugca agcauuucac     1440

aagucaacga aaaaaucaau caaucauuag cauucauccg aaaaucagac gaauuauuac     1500

acaacguaaa cgccggaaaa ucaaccacua auauaaugau aaccacaaua aucaucguaa     1560

uaauaguaau acuucucuca cuaaucgcag ucggacuccu ucuauacugc aaagcaagau     1620

cuacaccagu aacacuaucc aaagaucaac uaaguggcau aaacaacaua gcauuuucua     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2454
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2454
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuaaaagc caacgcgauc accacaaucc      120

ugacagccgu caccuucugc uucgccuccg gccaaaacau caccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aagggcuacc ugggcgcacu ucguacaggc ugguacaccu      240

ccguaauaac caucgaacuc uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaagcaa gaacuugaca aauacaaaaa ugcagucacc gaccuucaac      360

uccucaugca aucuaccccc gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggugaag uaaacaaaau aaaauccgcc cuccucucca      480

ccaacaaagc cgucgucucc cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg      540

accugaaaaa cuacauagac aaacagcucc uaccaauccu uaacaaacag agcugcucca      600

uuccgaauau cgaaacggua aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa      660

cgcgagaguu cuccguaaac gcuggcguca ccacacccgu cagcaccuac augcuaacga      720

acuccgaacu cuugucgcuc aucaacgaca ugcccauaac caacgaccaa aagaaacuaa      780

uguccaauaa cguacaaauc guacgccaac aaucuuacuc caucaugugc aucauaaaag      840

aagaaguacu agcuuacguc guccaacucc cacuguacgg agucaucgac acccccugcu      900

ggaaacucca caccucuccc cucugcacca ccaacaccaa agagggcucc aacauuugcc      960

ugacacgcac cgaccgcggc ugguacugcg acaacgcagg cuccgucucg uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaagucaau cuaugcaacg uagacaucuu caacccgaaa uaugacugca     1140

aaauuaugac aucuaaaacc gacguguccu ccucagucau cacuucccua ggagccaucg     1200

uuuccuguua cggcaagacc aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa     1260

ccuucuccaa cggaugugac uaugucucca acaagggcgu cgacaccguc agcgucggca     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu cuacgucaaa ggagagccca     1380

uaaucaacuu cuacgacccc cucgucuucc cauccgacga guucgacgcc ucaaucuccc     1440

aagucaacga gaaaaucaac caauccuuag ccuucauccg uaaguccgac gaacuccuuc     1500

acaacgucaa cgccgguaaa ucuaccacca acaucaugau aacaacaaua auuaucguca     1560

ucaucgucau ccuccuuucc cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu     1620

ccaccccagu aacccucucu aaagaccaac ucagcggaau caauaacaua gccuucagca     1680

auuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  2455
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2455
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2456
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2456
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2457
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2457
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2458
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2458
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2459
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2459
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2460
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2460
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2461
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2461
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagcaaac gcaauuacaa cuauacuuac cgccguaaca      180

uuuugcuucg caucugggca aaacauuacc gaagaauuuu aucaaucaac augcucagca      240

gucuccaaag gauaccuugg agcauuaaga accggcuggu auaccuccgu aauaacaauu      300

gaacuaucua auauaaaaga aaauaaaugu aauggaacug acgcaaaagu uaaacuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagacc uacaacuacu aaugcaauca      420

acccccgcaa caggaucagg auccgcaauc ugcagcggcg ucgcaguuug caaaguccua      480

cauuuagaag gagaaguaaa caaaauaaaa ucugcucucc ucucuacaaa caaagcagua      540

gugucacuuu caaacggagu aucaguucua acauucaaag uacuagaccu aaaaaauuac      600

auagacaaac aacuacuucc aauucuaaac aaacaauccu guuccauacc caacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agacuccuag aaauuacaag agaauuuucc      720

gucaaugcag gaguaacaac cccaguauca accuacaugu uaacuaacuc agaacucuua      780

ucacuaauaa acgacaugcc aaucacuaau gaccaaaaaa aacucauguc aaauaacgua      840

caaauagucc gacaacaauc auacuccauc augugcauua uaaaagaaga aguacuagca      900

uacgucgucc aauuaccacu auacggcguc auagacacac cauguuggaa acuccacaca      960

ucaccacuau gcacuacaaa uacaaaagaa ggcuccaaca ucugccuaac aagaacagac     1020

agagguuggu auugcgacaa cgcaggauca guaucauuuu ucccccaagc agaaacaugu     1080

aaaguacaau caaauagagu cuucugcgac accaugaacu cauuaacacu accuucagaa     1140

gucaaccuau gcaacguaga caucuucaac ccuaaauaug acugcaaaau caugaccagc     1200

aaaaccgacg uuucaucuuc cguaauaaca ucacuaggcg caauagucuc auguuacggc     1260

aaaacaaaau guacagcauc aaauaaaaac cguggaauaa uaaaaacauu uucuaauggu     1320

ugugacuacg uaagcaauaa aggaguagau acaguaucag ucggcaacac cuuauacugu     1380

guaaacaaac aagaaggcca aaguuuauac gucaaaggag aacccaucau caacuucuac     1440

gacccauuag uauucccauc agacgaauuu gaugcaagca uuucacaagu caacgaaaaa     1500

aucaaucaau cauuagcauu cauccgaaaa ucagacgaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa ccacuaauau aaugauaacc acaauaauca ucguaauaau aguaauacuu     1620

cucucacuaa ucgcagucgg acuccuucua uacugcaaag caagaucuac accaguaaca     1680

cuauccaaag aucaacuaag uggcauaaac aacauagcau uuucuaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2462
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2462
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu aaaagccaac gcgaucacca caauccugac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaagaguucu accaauccac augcuccgcc      240

gucuccaagg gcuaccuggg cgcacuucgu acaggcuggu acaccuccgu aauaaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aagcaagaac uugacaaaua caaaaaugca gucaccgacc uucaacuccu caugcaaucu      420

acccccgcca caggcuccgg cuccgcuauc ugcuccggcg ucgccgucug caaaguccuc      480

caccucgaag gugaaguaaa caaaauaaaa uccgcccucc ucuccaccaa caaagccguc      540

gucucccuau caaacggcgu cuccgugcuc accuucaagg uucucgaccu gaaaaacuac      600

auagacaaac agcuccuacc aauccuuaac aaacagagcu gcuccauucc gaauaucgaa      660

acgguaaucg aauuucaaca gaaaaacaac cgccuccucg aaauaacgcg agaguucucc      720

guaaacgcug gcgucaccac acccgucagc accuacaugc uaacgaacuc cgaacucuug      780

ucgcucauca acgacaugcc cauaaccaac gaccaaaaga aacuaauguc caauaacgua      840

caaaucguac gccaacaauc uuacuccauc augugcauca uaaaagaaga aguacuagcu      900

uacgucgucc aacucccacu guacggaguc aucgacaccc ccugcuggaa acuccacacc      960

ucuccccucu gcaccaccaa caccaaagag ggcuccaaca uuugccugac acgcaccgac     1020

cgcggcuggu acugcgacaa cgcaggcucc gucucguucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgaa     1140

gucaaucuau gcaacguaga caucuucaac ccgaaauaug acugcaaaau uaugacaucu     1200

aaaaccgacg uguccuccuc agucaucacu ucccuaggag ccaucguuuc cuguuacggc     1260

aagaccaaau gcaccgccag caacaaaaac cgaggcauca ucaaaaccuu cuccaacgga     1320

ugugacuaug ucuccaacaa gggcgucgac accgucagcg ucggcaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccucuac gucaaaggag agcccauaau caacuucuac     1440

gacccccucg ucuucccauc cgacgaguuc gacgccucaa ucucccaagu caacgagaaa     1500

aucaaccaau ccuuagccuu cauccguaag uccgacgaac uccuucacaa cgucaacgcc     1560

gguaaaucua ccaccaacau caugauaaca acaauaauua ucgucaucau cgucauccuc     1620

cuuucccuca ucgcggucgg gcuauugcuc uacugcaaag cccgguccac cccaguaacc     1680

cucucuaaag accaacucag cggaaucaau aacauagccu ucagcaauua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  2463
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2463
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2464
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2464
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2465
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2465
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2466
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2466
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2467
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2467
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2468
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2468
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2469
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2469
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagca      120

aacgcaauua caacuauacu uaccgccgua acauuuugcu ucgcaucugg gcaaaacauu      180

accgaagaau uuuaucaauc aacaugcuca gcagucucca aaggauaccu uggagcauua      240

agaaccggcu gguauaccuc cguaauaaca auugaacuau cuaauauaaa agaaaauaaa      300

uguaauggaa cugacgcaaa aguuaaacua auaaaacaag aacucgacaa auacaaaaac      360

gccgucacag accuacaacu acuaaugcaa ucaacccccg caacaggauc aggauccgca      420

aucugcagcg gcgucgcagu uugcaaaguc cuacauuuag aaggagaagu aaacaaaaua      480

aaaucugcuc uccucucuac aaacaaagca guagugucac uuucaaacgg aguaucaguu      540

cuaacauuca aaguacuaga ccuaaaaaau uacauagaca aacaacuacu uccaauucua      600

aacaaacaau ccuguuccau acccaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagacucc uagaaauuac aagagaauuu uccgucaaug caggaguaac aaccccagua      720

ucaaccuaca uguuaacuaa cucagaacuc uuaucacuaa uaaacgacau gccaaucacu      780

aaugaccaaa aaaaacucau gucaaauaac guacaaauag uccgacaaca aucauacucc      840

aucaugugca uuauaaaaga agaaguacua gcauacgucg uccaauuacc acuauacggc      900

gucauagaca caccauguug gaaacuccac acaucaccac uaugcacuac aaauacaaaa      960

gaaggcucca acaucugccu aacaagaaca gacagagguu gguauugcga caacgcagga     1020

ucaguaucau uuuuccccca agcagaaaca uguaaaguac aaucaaauag agucuucugc     1080

gacaccauga acucauuaac acuaccuuca gaagucaacc uaugcaacgu agacaucuuc     1140

aacccuaaau augacugcaa aaucaugacc agcaaaaccg acguuucauc uuccguaaua     1200

acaucacuag gcgcaauagu cucauguuac ggcaaaacaa aauguacagc aucaaauaaa     1260

aaccguggaa uaauaaaaac auuuucuaau gguugugacu acguaagcaa uaaaggagua     1320

gauacaguau cagucggcaa caccuuauac uguguaaaca aacaagaagg ccaaaguuua     1380

uacgucaaag gagaacccau caucaacuuc uacgacccau uaguauuccc aucagacgaa     1440

uuugaugcaa gcauuucaca agucaacgaa aaaaucaauc aaucauuagc auucauccga     1500

aaaucagacg aauuauuaca caacguaaac gccggaaaau caaccacuaa uauaaugaua     1560

accacaauaa ucaucguaau aauaguaaua cuucucucac uaaucgcagu cggacuccuu     1620

cuauacugca aagcaagauc uacaccagua acacuaucca aagaucaacu aaguggcaua     1680

aacaacauag cauuuucuaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2470
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2470
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuaaaagcc      120

aacgcgauca ccacaauccu gacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca agggcuaccu gggcgcacuu      240

cguacaggcu gguacaccuc cguaauaacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaagcaag aacuugacaa auacaaaaau      360

gcagucaccg accuucaacu ccucaugcaa ucuacccccg ccacaggcuc cggcuccgcu      420

aucugcuccg gcgucgccgu cugcaaaguc cuccaccucg aaggugaagu aaacaaaaua      480

aaauccgccc uccucuccac caacaaagcc gucgucuccc uaucaaacgg cgucuccgug      540

cucaccuuca agguucucga ccugaaaaac uacauagaca aacagcuccu accaauccuu      600

aacaaacaga gcugcuccau uccgaauauc gaaacgguaa ucgaauuuca acagaaaaac      660

aaccgccucc ucgaaauaac gcgagaguuc uccguaaacg cuggcgucac cacacccguc      720

agcaccuaca ugcuaacgaa cuccgaacuc uugucgcuca ucaacgacau gcccauaacc      780

aacgaccaaa agaaacuaau guccaauaac guacaaaucg uacgccaaca aucuuacucc      840

aucaugugca ucauaaaaga agaaguacua gcuuacgucg uccaacuccc acuguacgga      900

gucaucgaca cccccugcug gaaacuccac accucucccc ucugcaccac caacaccaaa      960

gagggcucca acauuugccu gacacgcacc gaccgcggcu gguacugcga caacgcaggc     1020

uccgucucgu ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaagucaauc uaugcaacgu agacaucuuc     1140

aacccgaaau augacugcaa aauuaugaca ucuaaaaccg acguguccuc cucagucauc     1200

acuucccuag gagccaucgu uuccuguuac ggcaagacca aaugcaccgc cagcaacaaa     1260

aaccgaggca ucaucaaaac cuucuccaac ggaugugacu augucuccaa caagggcguc     1320

gacaccguca gcgucggcaa cacccucuac ugcgucaaca aacaagaagg ccaaucccuc     1380

uacgucaaag gagagcccau aaucaacuuc uacgaccccc ucgucuuccc auccgacgag     1440

uucgacgccu caaucuccca agucaacgag aaaaucaacc aauccuuagc cuucauccgu     1500

aaguccgacg aacuccuuca caacgucaac gccgguaaau cuaccaccaa caucaugaua     1560

acaacaauaa uuaucgucau caucgucauc cuccuuuccc ucaucgcggu cgggcuauug     1620

cucuacugca aagcccgguc caccccagua acccucucua aagaccaacu cagcggaauc     1680

aauaacauag ccuucagcaa uuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2471
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2471
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2472
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2472
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2473
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2473
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2474
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2474
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2475
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2475
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2476
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2476
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2477
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2477
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagcaaac gcaauuacaa cuauacuuac cgccguaaca      180

uuuugcuucg caucugggca aaacauuacc gaagaauuuu aucaaucaac augcucagca      240

gucuccaaag gauaccuugg agcauuaaga accggcuggu auaccuccgu aauaacaauu      300

gaacuaucua auauaaaaga aaauaaaugu aauggaacug acgcaaaagu uaaacuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagacc uacaacuacu aaugcaauca      420

acccccgcaa caggaucagg auccgcaauc ugcagcggcg ucgcaguuug caaaguccua      480

cauuuagaag gagaaguaaa caaaauaaaa ucugcucucc ucucuacaaa caaagcagua      540

gugucacuuu caaacggagu aucaguucua acauucaaag uacuagaccu aaaaaauuac      600

auagacaaac aacuacuucc aauucuaaac aaacaauccu guuccauacc caacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agacuccuag aaauuacaag agaauuuucc      720

gucaaugcag gaguaacaac cccaguauca accuacaugu uaacuaacuc agaacucuua      780

ucacuaauaa acgacaugcc aaucacuaau gaccaaaaaa aacucauguc aaauaacgua      840

caaauagucc gacaacaauc auacuccauc augugcauua uaaaagaaga aguacuagca      900

uacgucgucc aauuaccacu auacggcguc auagacacac cauguuggaa acuccacaca      960

ucaccacuau gcacuacaaa uacaaaagaa ggcuccaaca ucugccuaac aagaacagac     1020

agagguuggu auugcgacaa cgcaggauca guaucauuuu ucccccaagc agaaacaugu     1080

aaaguacaau caaauagagu cuucugcgac accaugaacu cauuaacacu accuucagaa     1140

gucaaccuau gcaacguaga caucuucaac ccuaaauaug acugcaaaau caugaccagc     1200

aaaaccgacg uuucaucuuc cguaauaaca ucacuaggcg caauagucuc auguuacggc     1260

aaaacaaaau guacagcauc aaauaaaaac cguggaauaa uaaaaacauu uucuaauggu     1320

ugugacuacg uaagcaauaa aggaguagau acaguaucag ucggcaacac cuuauacugu     1380

guaaacaaac aagaaggcca aaguuuauac gucaaaggag aacccaucau caacuucuac     1440

gacccauuag uauucccauc agacgaauuu gaugcaagca uuucacaagu caacgaaaaa     1500

aucaaucaau cauuagcauu cauccgaaaa ucagacgaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa ccacuaauau aaugauaacc acaauaauca ucguaauaau aguaauacuu     1620

cucucacuaa ucgcagucgg acuccuucua uacugcaaag caagaucuac accaguaaca     1680

cuauccaaag aucaacuaag uggcauaaac aacauagcau uuucuaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2478
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2478
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu aaaagccaac gcgaucacca caauccugac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaagaguucu accaauccac augcuccgcc      240

gucuccaagg gcuaccuggg cgcacuucgu acaggcuggu acaccuccgu aauaaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aagcaagaac uugacaaaua caaaaaugca gucaccgacc uucaacuccu caugcaaucu      420

acccccgcca caggcuccgg cuccgcuauc ugcuccggcg ucgccgucug caaaguccuc      480

caccucgaag gugaaguaaa caaaauaaaa uccgcccucc ucuccaccaa caaagccguc      540

gucucccuau caaacggcgu cuccgugcuc accuucaagg uucucgaccu gaaaaacuac      600

auagacaaac agcuccuacc aauccuuaac aaacagagcu gcuccauucc gaauaucgaa      660

acgguaaucg aauuucaaca gaaaaacaac cgccuccucg aaauaacgcg agaguucucc      720

guaaacgcug gcgucaccac acccgucagc accuacaugc uaacgaacuc cgaacucuug      780

ucgcucauca acgacaugcc cauaaccaac gaccaaaaga aacuaauguc caauaacgua      840

caaaucguac gccaacaauc uuacuccauc augugcauca uaaaagaaga aguacuagcu      900

uacgucgucc aacucccacu guacggaguc aucgacaccc ccugcuggaa acuccacacc      960

ucuccccucu gcaccaccaa caccaaagag ggcuccaaca uuugccugac acgcaccgac     1020

cgcggcuggu acugcgacaa cgcaggcucc gucucguucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgaa     1140

gucaaucuau gcaacguaga caucuucaac ccgaaauaug acugcaaaau uaugacaucu     1200

aaaaccgacg uguccuccuc agucaucacu ucccuaggag ccaucguuuc cuguuacggc     1260

aagaccaaau gcaccgccag caacaaaaac cgaggcauca ucaaaaccuu cuccaacgga     1320

ugugacuaug ucuccaacaa gggcgucgac accgucagcg ucggcaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccucuac gucaaaggag agcccauaau caacuucuac     1440

gacccccucg ucuucccauc cgacgaguuc gacgccucaa ucucccaagu caacgagaaa     1500

aucaaccaau ccuuagccuu cauccguaag uccgacgaac uccuucacaa cgucaacgcc     1560

gguaaaucua ccaccaacau caugauaaca acaauaauua ucgucaucau cgucauccuc     1620

cuuucccuca ucgcggucgg gcuauugcuc uacugcaaag cccgguccac cccaguaacc     1680

cucucuaaag accaacucag cggaaucaau aacauagccu ucagcaauua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  2479
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2479
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2480
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2480
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2481
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2481
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2482
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2482
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2483
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2483
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2484
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2484
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2485
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2485
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagca      120

aacgcaauua caacuauacu uaccgccgua acauuuugcu ucgcaucugg gcaaaacauu      180

accgaagaau uuuaucaauc aacaugcuca gcagucucca aaggauaccu uggagcauua      240

agaaccggcu gguauaccuc cguaauaaca auugaacuau cuaauauaaa agaaaauaaa      300

uguaauggaa cugacgcaaa aguuaaacua auaaaacaag aacucgacaa auacaaaaac      360

gccgucacag accuacaacu acuaaugcaa ucaacccccg caacaggauc aggauccgca      420

aucugcagcg gcgucgcagu uugcaaaguc cuacauuuag aaggagaagu aaacaaaaua      480

aaaucugcuc uccucucuac aaacaaagca guagugucac uuucaaacgg aguaucaguu      540

cuaacauuca aaguacuaga ccuaaaaaau uacauagaca aacaacuacu uccaauucua      600

aacaaacaau ccuguuccau acccaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagacucc uagaaauuac aagagaauuu uccgucaaug caggaguaac aaccccagua      720

ucaaccuaca uguuaacuaa cucagaacuc uuaucacuaa uaaacgacau gccaaucacu      780

aaugaccaaa aaaaacucau gucaaauaac guacaaauag uccgacaaca aucauacucc      840

aucaugugca uuauaaaaga agaaguacua gcauacgucg uccaauuacc acuauacggc      900

gucauagaca caccauguug gaaacuccac acaucaccac uaugcacuac aaauacaaaa      960

gaaggcucca acaucugccu aacaagaaca gacagagguu gguauugcga caacgcagga     1020

ucaguaucau uuuuccccca agcagaaaca uguaaaguac aaucaaauag agucuucugc     1080

gacaccauga acucauuaac acuaccuuca gaagucaacc uaugcaacgu agacaucuuc     1140

aacccuaaau augacugcaa aaucaugacc agcaaaaccg acguuucauc uuccguaaua     1200

acaucacuag gcgcaauagu cucauguuac ggcaaaacaa aauguacagc aucaaauaaa     1260

aaccguggaa uaauaaaaac auuuucuaau gguugugacu acguaagcaa uaaaggagua     1320

gauacaguau cagucggcaa caccuuauac uguguaaaca aacaagaagg ccaaaguuua     1380

uacgucaaag gagaacccau caucaacuuc uacgacccau uaguauuccc aucagacgaa     1440

uuugaugcaa gcauuucaca agucaacgaa aaaaucaauc aaucauuagc auucauccga     1500

aaaucagacg aauuauuaca caacguaaac gccggaaaau caaccacuaa uauaaugaua     1560

accacaauaa ucaucguaau aauaguaaua cuucucucac uaaucgcagu cggacuccuu     1620

cuauacugca aagcaagauc uacaccagua acacuaucca aagaucaacu aaguggcaua     1680

aacaacauag cauuuucuaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2486
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2486
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuaaaagcc      120

aacgcgauca ccacaauccu gacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca agggcuaccu gggcgcacuu      240

cguacaggcu gguacaccuc cguaauaacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaagcaag aacuugacaa auacaaaaau      360

gcagucaccg accuucaacu ccucaugcaa ucuacccccg ccacaggcuc cggcuccgcu      420

aucugcuccg gcgucgccgu cugcaaaguc cuccaccucg aaggugaagu aaacaaaaua      480

aaauccgccc uccucuccac caacaaagcc gucgucuccc uaucaaacgg cgucuccgug      540

cucaccuuca agguucucga ccugaaaaac uacauagaca aacagcuccu accaauccuu      600

aacaaacaga gcugcuccau uccgaauauc gaaacgguaa ucgaauuuca acagaaaaac      660

aaccgccucc ucgaaauaac gcgagaguuc uccguaaacg cuggcgucac cacacccguc      720

agcaccuaca ugcuaacgaa cuccgaacuc uugucgcuca ucaacgacau gcccauaacc      780

aacgaccaaa agaaacuaau guccaauaac guacaaaucg uacgccaaca aucuuacucc      840

aucaugugca ucauaaaaga agaaguacua gcuuacgucg uccaacuccc acuguacgga      900

gucaucgaca cccccugcug gaaacuccac accucucccc ucugcaccac caacaccaaa      960

gagggcucca acauuugccu gacacgcacc gaccgcggcu gguacugcga caacgcaggc     1020

uccgucucgu ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaagucaauc uaugcaacgu agacaucuuc     1140

aacccgaaau augacugcaa aauuaugaca ucuaaaaccg acguguccuc cucagucauc     1200

acuucccuag gagccaucgu uuccuguuac ggcaagacca aaugcaccgc cagcaacaaa     1260

aaccgaggca ucaucaaaac cuucuccaac ggaugugacu augucuccaa caagggcguc     1320

gacaccguca gcgucggcaa cacccucuac ugcgucaaca aacaagaagg ccaaucccuc     1380

uacgucaaag gagagcccau aaucaacuuc uacgaccccc ucgucuuccc auccgacgag     1440

uucgacgccu caaucuccca agucaacgag aaaaucaacc aauccuuagc cuucauccgu     1500

aaguccgacg aacuccuuca caacgucaac gccgguaaau cuaccaccaa caucaugaua     1560

acaacaauaa uuaucgucau caucgucauc cuccuuuccc ucaucgcggu cgggcuauug     1620

cucuacugca aagcccgguc caccccagua acccucucua aagaccaacu cagcggaauc     1680

aauaacauag ccuucagcaa uuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  2487
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2487
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2488
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2488
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2489
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2489
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2490
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2490
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2491
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2491
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2492
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2492
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2493
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2493
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagca      120

aacgcaauua caacuauacu uaccgccgua acauuuugcu ucgcaucugg gcaaaacauu      180

accgaagaau uuuaucaauc aacaugcuca gcagucucca aaggauaccu uggagcauua      240

agaaccggcu gguauaccuc cguaauaaca auugaacuau cuaauauaaa agaaaauaaa      300

uguaauggaa cugacgcaaa aguuaaacua auaaaacaag aacucgacaa auacaaaaac      360

gccgucacag accuacaacu acuaaugcaa ucaacccccg caacaggauc aggauccgca      420

aucugcagcg gcgucgcagu uugcaaaguc cuacauuuag aaggagaagu aaacaaaaua      480

aaaucugcuc uccucucuac aaacaaagca guagugucac uuucaaacgg aguaucaguu      540

cuaacauuca aaguacuaga ccuaaaaaau uacauagaca aacaacuacu uccaauucua      600

aacaaacaau ccuguuccau acccaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagacucc uagaaauuac aagagaauuu uccgucaaug caggaguaac aaccccagua      720

ucaaccuaca uguuaacuaa cucagaacuc uuaucacuaa uaaacgacau gccaaucacu      780

aaugaccaaa aaaaacucau gucaaauaac guacaaauag uccgacaaca aucauacucc      840

aucaugugca uuauaaaaga agaaguacua gcauacgucg uccaauuacc acuauacggc      900

gucauagaca caccauguug gaaacuccac acaucaccac uaugcacuac aaauacaaaa      960

gaaggcucca acaucugccu aacaagaaca gacagagguu gguauugcga caacgcagga     1020

ucaguaucau uuuuccccca agcagaaaca uguaaaguac aaucaaauag agucuucugc     1080

gacaccauga acucauuaac acuaccuuca gaagucaacc uaugcaacgu agacaucuuc     1140

aacccuaaau augacugcaa aaucaugacc agcaaaaccg acguuucauc uuccguaaua     1200

acaucacuag gcgcaauagu cucauguuac ggcaaaacaa aauguacagc aucaaauaaa     1260

aaccguggaa uaauaaaaac auuuucuaau gguugugacu acguaagcaa uaaaggagua     1320

gauacaguau cagucggcaa caccuuauac uguguaaaca aacaagaagg ccaaaguuua     1380

uacgucaaag gagaacccau caucaacuuc uacgacccau uaguauuccc aucagacgaa     1440

uuugaugcaa gcauuucaca agucaacgaa aaaaucaauc aaucauuagc auucauccga     1500

aaaucagacg aauuauuaca caacguaaac gccggaaaau caaccacuaa uauaaugaua     1560

accacaauaa ucaucguaau aauaguaaua cuucucucac uaaucgcagu cggacuccuu     1620

cuauacugca aagcaagauc uacaccagua acacuaucca aagaucaacu aaguggcaua     1680

aacaacauag cauuuucuaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2494
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2494
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuaaaagcc      120

aacgcgauca ccacaauccu gacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca agggcuaccu gggcgcacuu      240

cguacaggcu gguacaccuc cguaauaacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaagcaag aacuugacaa auacaaaaau      360

gcagucaccg accuucaacu ccucaugcaa ucuacccccg ccacaggcuc cggcuccgcu      420

aucugcuccg gcgucgccgu cugcaaaguc cuccaccucg aaggugaagu aaacaaaaua      480

aaauccgccc uccucuccac caacaaagcc gucgucuccc uaucaaacgg cgucuccgug      540

cucaccuuca agguucucga ccugaaaaac uacauagaca aacagcuccu accaauccuu      600

aacaaacaga gcugcuccau uccgaauauc gaaacgguaa ucgaauuuca acagaaaaac      660

aaccgccucc ucgaaauaac gcgagaguuc uccguaaacg cuggcgucac cacacccguc      720

agcaccuaca ugcuaacgaa cuccgaacuc uugucgcuca ucaacgacau gcccauaacc      780

aacgaccaaa agaaacuaau guccaauaac guacaaaucg uacgccaaca aucuuacucc      840

aucaugugca ucauaaaaga agaaguacua gcuuacgucg uccaacuccc acuguacgga      900

gucaucgaca cccccugcug gaaacuccac accucucccc ucugcaccac caacaccaaa      960

gagggcucca acauuugccu gacacgcacc gaccgcggcu gguacugcga caacgcaggc     1020

uccgucucgu ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaagucaauc uaugcaacgu agacaucuuc     1140

aacccgaaau augacugcaa aauuaugaca ucuaaaaccg acguguccuc cucagucauc     1200

acuucccuag gagccaucgu uuccuguuac ggcaagacca aaugcaccgc cagcaacaaa     1260

aaccgaggca ucaucaaaac cuucuccaac ggaugugacu augucuccaa caagggcguc     1320

gacaccguca gcgucggcaa cacccucuac ugcgucaaca aacaagaagg ccaaucccuc     1380

uacgucaaag gagagcccau aaucaacuuc uacgaccccc ucgucuuccc auccgacgag     1440

uucgacgccu caaucuccca agucaacgag aaaaucaacc aauccuuagc cuucauccgu     1500

aaguccgacg aacuccuuca caacgucaac gccgguaaau cuaccaccaa caucaugaua     1560

acaacaauaa uuaucgucau caucgucauc cuccuuuccc ucaucgcggu cgggcuauug     1620

cucuacugca aagcccgguc caccccagua acccucucua aagaccaacu cagcggaauc     1680

aauaacauag ccuucagcaa uuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  2495
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2495
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2496
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2496
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2497
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2497
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2498
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2498
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2499
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2499
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2500
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2500
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2501
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2501
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agcaaacgca      120

auuacaacua uacuuaccgc cguaacauuu ugcuucgcau cugggcaaaa cauuaccgaa      180

gaauuuuauc aaucaacaug cucagcaguc uccaaaggau accuuggagc auuaagaacc      240

ggcugguaua ccuccguaau aacaauugaa cuaucuaaua uaaaagaaaa uaaauguaau      300

ggaacugacg caaaaguuaa acuaauaaaa caagaacucg acaaauacaa aaacgccguc      360

acagaccuac aacuacuaau gcaaucaacc cccgcaacag gaucaggauc cgcaaucugc      420

agcggcgucg caguuugcaa aguccuacau uuagaaggag aaguaaacaa aauaaaaucu      480

gcucuccucu cuacaaacaa agcaguagug ucacuuucaa acggaguauc aguucuaaca      540

uucaaaguac uagaccuaaa aaauuacaua gacaaacaac uacuuccaau ucuaaacaaa      600

caauccuguu ccauacccaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

cuccuagaaa uuacaagaga auuuuccguc aaugcaggag uaacaacccc aguaucaacc      720

uacauguuaa cuaacucaga acucuuauca cuaauaaacg acaugccaau cacuaaugac      780

caaaaaaaac ucaugucaaa uaacguacaa auaguccgac aacaaucaua cuccaucaug      840

ugcauuauaa aagaagaagu acuagcauac gucguccaau uaccacuaua cggcgucaua      900

gacacaccau guuggaaacu ccacacauca ccacuaugca cuacaaauac aaaagaaggc      960

uccaacaucu gccuaacaag aacagacaga gguugguauu gcgacaacgc aggaucagua     1020

ucauuuuucc cccaagcaga aacauguaaa guacaaucaa auagagucuu cugcgacacc     1080

augaacucau uaacacuacc uucagaaguc aaccuaugca acguagacau cuucaacccu     1140

aaauaugacu gcaaaaucau gaccagcaaa accgacguuu caucuuccgu aauaacauca     1200

cuaggcgcaa uagucucaug uuacggcaaa acaaaaugua cagcaucaaa uaaaaaccgu     1260

ggaauaauaa aaacauuuuc uaaugguugu gacuacguaa gcaauaaagg aguagauaca     1320

guaucagucg gcaacaccuu auacugugua aacaaacaag aaggccaaag uuuauacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccauuaguau ucccaucaga cgaauuugau     1440

gcaagcauuu cacaagucaa cgaaaaaauc aaucaaucau uagcauucau ccgaaaauca     1500

gacgaauuau uacacaacgu aaacgccgga aaaucaacca cuaauauaau gauaaccaca     1560

auaaucaucg uaauaauagu aauacuucuc ucacuaaucg cagucggacu ccuucuauac     1620

ugcaaagcaa gaucuacacc aguaacacua uccaaagauc aacuaagugg cauaaacaac     1680

auagcauuuu cuaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2502
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2502
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuaaa agccaacgcg      120

aucaccacaa uccugacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaagggcu accugggcgc acuucguaca      240

ggcugguaca ccuccguaau aaccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaag caagaacuug acaaauacaa aaaugcaguc      360

accgaccuuc aacuccucau gcaaucuacc cccgccacag gcuccggcuc cgcuaucugc      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggug aaguaaacaa aauaaaaucc      480

gcccuccucu ccaccaacaa agccgucguc ucccuaucaa acggcgucuc cgugcucacc      540

uucaagguuc ucgaccugaa aaacuacaua gacaaacagc uccuaccaau ccuuaacaaa      600

cagagcugcu ccauuccgaa uaucgaaacg guaaucgaau uucaacagaa aaacaaccgc      660

cuccucgaaa uaacgcgaga guucuccgua aacgcuggcg ucaccacacc cgucagcacc      720

uacaugcuaa cgaacuccga acucuugucg cucaucaacg acaugcccau aaccaacgac      780

caaaagaaac uaauguccaa uaacguacaa aucguacgcc aacaaucuua cuccaucaug      840

ugcaucauaa aagaagaagu acuagcuuac gucguccaac ucccacugua cggagucauc      900

gacacccccu gcuggaaacu ccacaccucu ccccucugca ccaccaacac caaagagggc      960

uccaacauuu gccugacacg caccgaccgc ggcugguacu gcgacaacgc aggcuccguc     1020

ucguucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgaaguc aaucuaugca acguagacau cuucaacccg     1140

aaauaugacu gcaaaauuau gacaucuaaa accgacgugu ccuccucagu caucacuucc     1200

cuaggagcca ucguuuccug uuacggcaag accaaaugca ccgccagcaa caaaaaccga     1260

ggcaucauca aaaccuucuc caacggaugu gacuaugucu ccaacaaggg cgucgacacc     1320

gucagcgucg gcaacacccu cuacugcguc aacaaacaag aaggccaauc ccucuacguc     1380

aaaggagagc ccauaaucaa cuucuacgac ccccucgucu ucccauccga cgaguucgac     1440

gccucaaucu cccaagucaa cgagaaaauc aaccaauccu uagccuucau ccguaagucc     1500

gacgaacucc uucacaacgu caacgccggu aaaucuacca ccaacaucau gauaacaaca     1560

auaauuaucg ucaucaucgu cauccuccuu ucccucaucg cggucgggcu auugcucuac     1620

ugcaaagccc gguccacccc aguaacccuc ucuaaagacc aacucagcgg aaucaauaac     1680

auagccuuca gcaauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2503
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2503
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2504
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2504
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2505
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2505
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2506
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2506
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2507
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2507
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2508
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2508
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2509
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2509
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gcaaacgcaa uuacaacuau acuuaccgcc guaacauuuu gcuucgcauc ugggcaaaac      180

auuaccgaag aauuuuauca aucaacaugc ucagcagucu ccaaaggaua ccuuggagca      240

uuaagaaccg gcugguauac cuccguaaua acaauugaac uaucuaauau aaaagaaaau      300

aaauguaaug gaacugacgc aaaaguuaaa cuaauaaaac aagaacucga caaauacaaa      360

aacgccguca cagaccuaca acuacuaaug caaucaaccc ccgcaacagg aucaggaucc      420

gcaaucugca gcggcgucgc aguuugcaaa guccuacauu uagaaggaga aguaaacaaa      480

auaaaaucug cucuccucuc uacaaacaaa gcaguagugu cacuuucaaa cggaguauca      540

guucuaacau ucaaaguacu agaccuaaaa aauuacauag acaaacaacu acuuccaauu      600

cuaaacaaac aauccuguuc cauacccaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagac uccuagaaau uacaagagaa uuuuccguca augcaggagu aacaacccca      720

guaucaaccu acauguuaac uaacucagaa cucuuaucac uaauaaacga caugccaauc      780

acuaaugacc aaaaaaaacu caugucaaau aacguacaaa uaguccgaca acaaucauac      840

uccaucaugu gcauuauaaa agaagaagua cuagcauacg ucguccaauu accacuauac      900

ggcgucauag acacaccaug uuggaaacuc cacacaucac cacuaugcac uacaaauaca      960

aaagaaggcu ccaacaucug ccuaacaaga acagacagag guugguauug cgacaacgca     1020

ggaucaguau cauuuuuccc ccaagcagaa acauguaaag uacaaucaaa uagagucuuc     1080

ugcgacacca ugaacucauu aacacuaccu ucagaaguca accuaugcaa cguagacauc     1140

uucaacccua aauaugacug caaaaucaug accagcaaaa ccgacguuuc aucuuccgua     1200

auaacaucac uaggcgcaau agucucaugu uacggcaaaa caaaauguac agcaucaaau     1260

aaaaaccgug gaauaauaaa aacauuuucu aaugguugug acuacguaag caauaaagga     1320

guagauacag uaucagucgg caacaccuua uacuguguaa acaaacaaga aggccaaagu     1380

uuauacguca aaggagaacc caucaucaac uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug caagcauuuc acaagucaac gaaaaaauca aucaaucauu agcauucauc     1500

cgaaaaucag acgaauuauu acacaacgua aacgccggaa aaucaaccac uaauauaaug     1560

auaaccacaa uaaucaucgu aauaauagua auacuucucu cacuaaucgc agucggacuc     1620

cuucuauacu gcaaagcaag aucuacacca guaacacuau ccaaagauca acuaaguggc     1680

auaaacaaca uagcauuuuc uaacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2510
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2510
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuaaaa      120

gccaacgcga ucaccacaau ccugacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgaag aguucuacca auccacaugc uccgccgucu ccaagggcua ccugggcgca      240

cuucguacag gcugguacac cuccguaaua accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaagc aagaacuuga caaauacaaa      360

aaugcaguca ccgaccuuca acuccucaug caaucuaccc ccgccacagg cuccggcucc      420

gcuaucugcu ccggcgucgc cgucugcaaa guccuccacc ucgaagguga aguaaacaaa      480

auaaaauccg cccuccucuc caccaacaaa gccgucgucu cccuaucaaa cggcgucucc      540

gugcucaccu ucaagguucu cgaccugaaa aacuacauag acaaacagcu ccuaccaauc      600

cuuaacaaac agagcugcuc cauuccgaau aucgaaacgg uaaucgaauu ucaacagaaa      660

aacaaccgcc uccucgaaau aacgcgagag uucuccguaa acgcuggcgu caccacaccc      720

gucagcaccu acaugcuaac gaacuccgaa cucuugucgc ucaucaacga caugcccaua      780

accaacgacc aaaagaaacu aauguccaau aacguacaaa ucguacgcca acaaucuuac      840

uccaucaugu gcaucauaaa agaagaagua cuagcuuacg ucguccaacu cccacuguac      900

ggagucaucg acacccccug cuggaaacuc cacaccucuc cccucugcac caccaacacc      960

aaagagggcu ccaacauuug ccugacacgc accgaccgcg gcugguacug cgacaacgca     1020

ggcuccgucu cguucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgaaguca aucuaugcaa cguagacauc     1140

uucaacccga aauaugacug caaaauuaug acaucuaaaa ccgacguguc cuccucaguc     1200

aucacuuccc uaggagccau cguuuccugu uacggcaaga ccaaaugcac cgccagcaac     1260

aaaaaccgag gcaucaucaa aaccuucucc aacggaugug acuaugucuc caacaagggc     1320

gucgacaccg ucagcgucgg caacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cucuacguca aaggagagcc cauaaucaac uucuacgacc cccucgucuu cccauccgac     1440

gaguucgacg ccucaaucuc ccaagucaac gagaaaauca accaauccuu agccuucauc     1500

cguaaguccg acgaacuccu ucacaacguc aacgccggua aaucuaccac caacaucaug     1560

auaacaacaa uaauuaucgu caucaucguc auccuccuuu cccucaucgc ggucgggcua     1620

uugcucuacu gcaaagcccg guccacccca guaacccucu cuaaagacca acucagcgga     1680

aucaauaaca uagccuucag caauuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  2511
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2511
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2512
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2512
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2513
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2513
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2514
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2514
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2515
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2515
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2516
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2516
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2517
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2517
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agcaaacgca      120

auuacaacua uacuuaccgc cguaacauuu ugcuucgcau cugggcaaaa cauuaccgaa      180

gaauuuuauc aaucaacaug cucagcaguc uccaaaggau accuuggagc auuaagaacc      240

ggcugguaua ccuccguaau aacaauugaa cuaucuaaua uaaaagaaaa uaaauguaau      300

ggaacugacg caaaaguuaa acuaauaaaa caagaacucg acaaauacaa aaacgccguc      360

acagaccuac aacuacuaau gcaaucaacc cccgcaacag gaucaggauc cgcaaucugc      420

agcggcgucg caguuugcaa aguccuacau uuagaaggag aaguaaacaa aauaaaaucu      480

gcucuccucu cuacaaacaa agcaguagug ucacuuucaa acggaguauc aguucuaaca      540

uucaaaguac uagaccuaaa aaauuacaua gacaaacaac uacuuccaau ucuaaacaaa      600

caauccuguu ccauacccaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

cuccuagaaa uuacaagaga auuuuccguc aaugcaggag uaacaacccc aguaucaacc      720

uacauguuaa cuaacucaga acucuuauca cuaauaaacg acaugccaau cacuaaugac      780

caaaaaaaac ucaugucaaa uaacguacaa auaguccgac aacaaucaua cuccaucaug      840

ugcauuauaa aagaagaagu acuagcauac gucguccaau uaccacuaua cggcgucaua      900

gacacaccau guuggaaacu ccacacauca ccacuaugca cuacaaauac aaaagaaggc      960

uccaacaucu gccuaacaag aacagacaga gguugguauu gcgacaacgc aggaucagua     1020

ucauuuuucc cccaagcaga aacauguaaa guacaaucaa auagagucuu cugcgacacc     1080

augaacucau uaacacuacc uucagaaguc aaccuaugca acguagacau cuucaacccu     1140

aaauaugacu gcaaaaucau gaccagcaaa accgacguuu caucuuccgu aauaacauca     1200

cuaggcgcaa uagucucaug uuacggcaaa acaaaaugua cagcaucaaa uaaaaaccgu     1260

ggaauaauaa aaacauuuuc uaaugguugu gacuacguaa gcaauaaagg aguagauaca     1320

guaucagucg gcaacaccuu auacugugua aacaaacaag aaggccaaag uuuauacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccauuaguau ucccaucaga cgaauuugau     1440

gcaagcauuu cacaagucaa cgaaaaaauc aaucaaucau uagcauucau ccgaaaauca     1500

gacgaauuau uacacaacgu aaacgccgga aaaucaacca cuaauauaau gauaaccaca     1560

auaaucaucg uaauaauagu aauacuucuc ucacuaaucg cagucggacu ccuucuauac     1620

ugcaaagcaa gaucuacacc aguaacacua uccaaagauc aacuaagugg cauaaacaac     1680

auagcauuuu cuaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2518
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2518
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuaaa agccaacgcg      120

aucaccacaa uccugacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaagggcu accugggcgc acuucguaca      240

ggcugguaca ccuccguaau aaccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaag caagaacuug acaaauacaa aaaugcaguc      360

accgaccuuc aacuccucau gcaaucuacc cccgccacag gcuccggcuc cgcuaucugc      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggug aaguaaacaa aauaaaaucc      480

gcccuccucu ccaccaacaa agccgucguc ucccuaucaa acggcgucuc cgugcucacc      540

uucaagguuc ucgaccugaa aaacuacaua gacaaacagc uccuaccaau ccuuaacaaa      600

cagagcugcu ccauuccgaa uaucgaaacg guaaucgaau uucaacagaa aaacaaccgc      660

cuccucgaaa uaacgcgaga guucuccgua aacgcuggcg ucaccacacc cgucagcacc      720

uacaugcuaa cgaacuccga acucuugucg cucaucaacg acaugcccau aaccaacgac      780

caaaagaaac uaauguccaa uaacguacaa aucguacgcc aacaaucuua cuccaucaug      840

ugcaucauaa aagaagaagu acuagcuuac gucguccaac ucccacugua cggagucauc      900

gacacccccu gcuggaaacu ccacaccucu ccccucugca ccaccaacac caaagagggc      960

uccaacauuu gccugacacg caccgaccgc ggcugguacu gcgacaacgc aggcuccguc     1020

ucguucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgaaguc aaucuaugca acguagacau cuucaacccg     1140

aaauaugacu gcaaaauuau gacaucuaaa accgacgugu ccuccucagu caucacuucc     1200

cuaggagcca ucguuuccug uuacggcaag accaaaugca ccgccagcaa caaaaaccga     1260

ggcaucauca aaaccuucuc caacggaugu gacuaugucu ccaacaaggg cgucgacacc     1320

gucagcgucg gcaacacccu cuacugcguc aacaaacaag aaggccaauc ccucuacguc     1380

aaaggagagc ccauaaucaa cuucuacgac ccccucgucu ucccauccga cgaguucgac     1440

gccucaaucu cccaagucaa cgagaaaauc aaccaauccu uagccuucau ccguaagucc     1500

gacgaacucc uucacaacgu caacgccggu aaaucuacca ccaacaucau gauaacaaca     1560

auaauuaucg ucaucaucgu cauccuccuu ucccucaucg cggucgggcu auugcucuac     1620

ugcaaagccc gguccacccc aguaacccuc ucuaaagacc aacucagcgg aaucaauaac     1680

auagccuuca gcaauuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  2519
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2519
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2520
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2520
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2521
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2521
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2522
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2522
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2523
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2523
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2524
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2524
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2525
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2525
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagcaaa cgcaauuaca acuauacuua ccgccguaac auuuugcuuc      240

gcaucugggc aaaacauuac cgaagaauuu uaucaaucaa caugcucagc agucuccaaa      300

ggauaccuug gagcauuaag aaccggcugg uauaccuccg uaauaacaau ugaacuaucu      360

aauauaaaag aaaauaaaug uaauggaacu gacgcaaaag uuaaacuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cgucacagac cuacaacuac uaaugcaauc aacccccgca      480

acaggaucag gauccgcaau cugcagcggc gucgcaguuu gcaaaguccu acauuuagaa      540

ggagaaguaa acaaaauaaa aucugcucuc cucucuacaa acaaagcagu agugucacuu      600

ucaaacggag uaucaguucu aacauucaaa guacuagacc uaaaaaauua cauagacaaa      660

caacuacuuc caauucuaaa caaacaaucc uguuccauac ccaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagacuccua gaaauuacaa gagaauuuuc cgucaaugca      780

ggaguaacaa ccccaguauc aaccuacaug uuaacuaacu cagaacucuu aucacuaaua      840

aacgacaugc caaucacuaa ugaccaaaaa aaacucaugu caaauaacgu acaaauaguc      900

cgacaacaau cauacuccau caugugcauu auaaaagaag aaguacuagc auacgucguc      960

caauuaccac uauacggcgu cauagacaca ccauguugga aacuccacac aucaccacua     1020

ugcacuacaa auacaaaaga aggcuccaac aucugccuaa caagaacaga cagagguugg     1080

uauugcgaca acgcaggauc aguaucauuu uucccccaag cagaaacaug uaaaguacaa     1140

ucaaauagag ucuucugcga caccaugaac ucauuaacac uaccuucaga agucaaccua     1200

ugcaacguag acaucuucaa cccuaaauau gacugcaaaa ucaugaccag caaaaccgac     1260

guuucaucuu ccguaauaac aucacuaggc gcaauagucu cauguuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa ccguggaaua auaaaaacau uuucuaaugg uugugacuac     1380

guaagcaaua aaggaguaga uacaguauca gucggcaaca ccuuauacug uguaaacaaa     1440

caagaaggcc aaaguuuaua cgucaaagga gaacccauca ucaacuucua cgacccauua     1500

guauucccau cagacgaauu ugaugcaagc auuucacaag ucaacgaaaa aaucaaucaa     1560

ucauuagcau ucauccgaaa aucagacgaa uuauuacaca acguaaacgc cggaaaauca     1620

accacuaaua uaaugauaac cacaauaauc aucguaauaa uaguaauacu ucucucacua     1680

aucgcagucg gacuccuucu auacugcaaa gcaagaucua caccaguaac acuauccaaa     1740

gaucaacuaa guggcauaaa caacauagca uuuucuaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2526
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2526
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uaaaagccaa cgcgaucacc acaauccuga cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaagaguuc uaccaaucca caugcuccgc cgucuccaag      300

ggcuaccugg gcgcacuucg uacaggcugg uacaccuccg uaauaaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caagcaagaa      420

cuugacaaau acaaaaaugc agucaccgac cuucaacucc ucaugcaauc uacccccgcc      480

acaggcuccg gcuccgcuau cugcuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggugaaguaa acaaaauaaa auccgcccuc cucuccacca acaaagccgu cgucucccua      600

ucaaacggcg ucuccgugcu caccuucaag guucucgacc ugaaaaacua cauagacaaa      660

cagcuccuac caauccuuaa caaacagagc ugcuccauuc cgaauaucga aacgguaauc      720

gaauuucaac agaaaaacaa ccgccuccuc gaaauaacgc gagaguucuc cguaaacgcu      780

ggcgucacca cacccgucag caccuacaug cuaacgaacu ccgaacucuu gucgcucauc      840

aacgacaugc ccauaaccaa cgaccaaaag aaacuaaugu ccaauaacgu acaaaucgua      900

cgccaacaau cuuacuccau caugugcauc auaaaagaag aaguacuagc uuacgucguc      960

caacucccac uguacggagu caucgacacc cccugcugga aacuccacac cucuccccuc     1020

ugcaccacca acaccaaaga gggcuccaac auuugccuga cacgcaccga ccgcggcugg     1080

uacugcgaca acgcaggcuc cgucucguuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga agucaaucua     1200

ugcaacguag acaucuucaa cccgaaauau gacugcaaaa uuaugacauc uaaaaccgac     1260

guguccuccu cagucaucac uucccuagga gccaucguuu ccuguuacgg caagaccaaa     1320

ugcaccgcca gcaacaaaaa ccgaggcauc aucaaaaccu ucuccaacgg augugacuau     1380

gucuccaaca agggcgucga caccgucagc gucggcaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccucua cgucaaagga gagcccauaa ucaacuucua cgacccccuc     1500

gucuucccau ccgacgaguu cgacgccuca aucucccaag ucaacgagaa aaucaaccaa     1560

uccuuagccu ucauccguaa guccgacgaa cuccuucaca acgucaacgc cgguaaaucu     1620

accaccaaca ucaugauaac aacaauaauu aucgucauca ucgucauccu ccuuucccuc     1680

aucgcggucg ggcuauugcu cuacugcaaa gcccggucca ccccaguaac ccucucuaaa     1740

gaccaacuca gcggaaucaa uaacauagcc uucagcaauu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  2527
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2527
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2528
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2528
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2529
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2529
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2530
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2530
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2531
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2531
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2532
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2532
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2533
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2533
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac      120

uuaccgccgu aacauuuugc uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau      180

caacaugcuc agcagucucc aaaggauacc uuggagcauu aagaaccggc ugguauaccu      240

ccguaauaac aauugaacua ucuaauauaa aagaaaauaa auguaaugga acugacgcaa      300

aaguuaaacu aauaaaacaa gaacucgaca aauacaaaaa cgccgucaca gaccuacaac      360

uacuaaugca aucaaccccc gcaacaggau caggauccgc aaucugcagc ggcgucgcag      420

uuugcaaagu ccuacauuua gaaggagaag uaaacaaaau aaaaucugcu cuccucucua      480

caaacaaagc aguaguguca cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag      540

accuaaaaaa uuacauagac aaacaacuac uuccaauucu aaacaaacaa uccuguucca      600

uacccaacau agaaacagua auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua      660

caagagaauu uuccgucaau gcaggaguaa caaccccagu aucaaccuac auguuaacua      720

acucagaacu cuuaucacua auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca      780

ugucaaauaa cguacaaaua guccgacaac aaucauacuc caucaugugc auuauaaaag      840

aagaaguacu agcauacguc guccaauuac cacuauacgg cgucauagac acaccauguu      900

ggaaacucca cacaucacca cuaugcacua caaauacaaa agaaggcucc aacaucugcc      960

uaacaagaac agacagaggu ugguauugcg acaacgcagg aucaguauca uuuuuccccc     1020

aagcagaaac auguaaagua caaucaaaua gagucuucug cgacaccaug aacucauuaa     1080

cacuaccuuc agaagucaac cuaugcaacg uagacaucuu caacccuaaa uaugacugca     1140

aaaucaugac cagcaaaacc gacguuucau cuuccguaau aacaucacua ggcgcaauag     1200

ucucauguua cggcaaaaca aaauguacag caucaaauaa aaaccgugga auaauaaaaa     1260

cauuuucuaa ugguugugac uacguaagca auaaaggagu agauacagua ucagucggca     1320

acaccuuaua cuguguaaac aaacaagaag gccaaaguuu auacgucaaa ggagaaccca     1380

ucaucaacuu cuacgaccca uuaguauucc caucagacga auuugaugca agcauuucac     1440

aagucaacga aaaaaucaau caaucauuag cauucauccg aaaaucagac gaauuauuac     1500

acaacguaaa cgccggaaaa ucaaccacua auauaaugau aaccacaaua aucaucguaa     1560

uaauaguaau acuucucuca cuaaucgcag ucggacuccu ucuauacugc aaagcaagau     1620

cuacaccagu aacacuaucc aaagaucaac uaaguggcau aaacaacaua gcauuuucua     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2534
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2534
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuaaaagc caacgcgauc accacaaucc      120

ugacagccgu caccuucugc uucgccuccg gccaaaacau caccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aagggcuacc ugggcgcacu ucguacaggc ugguacaccu      240

ccguaauaac caucgaacuc uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaagcaa gaacuugaca aauacaaaaa ugcagucacc gaccuucaac      360

uccucaugca aucuaccccc gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggugaag uaaacaaaau aaaauccgcc cuccucucca      480

ccaacaaagc cgucgucucc cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg      540

accugaaaaa cuacauagac aaacagcucc uaccaauccu uaacaaacag agcugcucca      600

uuccgaauau cgaaacggua aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa      660

cgcgagaguu cuccguaaac gcuggcguca ccacacccgu cagcaccuac augcuaacga      720

acuccgaacu cuugucgcuc aucaacgaca ugcccauaac caacgaccaa aagaaacuaa      780

uguccaauaa cguacaaauc guacgccaac aaucuuacuc caucaugugc aucauaaaag      840

aagaaguacu agcuuacguc guccaacucc cacuguacgg agucaucgac acccccugcu      900

ggaaacucca caccucuccc cucugcacca ccaacaccaa agagggcucc aacauuugcc      960

ugacacgcac cgaccgcggc ugguacugcg acaacgcagg cuccgucucg uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaagucaau cuaugcaacg uagacaucuu caacccgaaa uaugacugca     1140

aaauuaugac aucuaaaacc gacguguccu ccucagucau cacuucccua ggagccaucg     1200

uuuccuguua cggcaagacc aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa     1260

ccuucuccaa cggaugugac uaugucucca acaagggcgu cgacaccguc agcgucggca     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu cuacgucaaa ggagagccca     1380

uaaucaacuu cuacgacccc cucgucuucc cauccgacga guucgacgcc ucaaucuccc     1440

aagucaacga gaaaaucaac caauccuuag ccuucauccg uaaguccgac gaacuccuuc     1500

acaacgucaa cgccgguaaa ucuaccacca acaucaugau aacaacaaua auuaucguca     1560

ucaucgucau ccuccuuucc cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu     1620

ccaccccagu aacccucucu aaagaccaac ucagcggaau caauaacaua gccuucagca     1680

auuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  2535
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2535
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2536
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2536
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2537
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2537
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2538
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2538
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2539
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2539
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2540
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2540
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2541
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2541
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagcaaa cgcaauuaca acuauacuua ccgccguaac auuuugcuuc      240

gcaucugggc aaaacauuac cgaagaauuu uaucaaucaa caugcucagc agucuccaaa      300

ggauaccuug gagcauuaag aaccggcugg uauaccuccg uaauaacaau ugaacuaucu      360

aauauaaaag aaaauaaaug uaauggaacu gacgcaaaag uuaaacuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cgucacagac cuacaacuac uaaugcaauc aacccccgca      480

acaggaucag gauccgcaau cugcagcggc gucgcaguuu gcaaaguccu acauuuagaa      540

ggagaaguaa acaaaauaaa aucugcucuc cucucuacaa acaaagcagu agugucacuu      600

ucaaacggag uaucaguucu aacauucaaa guacuagacc uaaaaaauua cauagacaaa      660

caacuacuuc caauucuaaa caaacaaucc uguuccauac ccaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagacuccua gaaauuacaa gagaauuuuc cgucaaugca      780

ggaguaacaa ccccaguauc aaccuacaug uuaacuaacu cagaacucuu aucacuaaua      840

aacgacaugc caaucacuaa ugaccaaaaa aaacucaugu caaauaacgu acaaauaguc      900

cgacaacaau cauacuccau caugugcauu auaaaagaag aaguacuagc auacgucguc      960

caauuaccac uauacggcgu cauagacaca ccauguugga aacuccacac aucaccacua     1020

ugcacuacaa auacaaaaga aggcuccaac aucugccuaa caagaacaga cagagguugg     1080

uauugcgaca acgcaggauc aguaucauuu uucccccaag cagaaacaug uaaaguacaa     1140

ucaaauagag ucuucugcga caccaugaac ucauuaacac uaccuucaga agucaaccua     1200

ugcaacguag acaucuucaa cccuaaauau gacugcaaaa ucaugaccag caaaaccgac     1260

guuucaucuu ccguaauaac aucacuaggc gcaauagucu cauguuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa ccguggaaua auaaaaacau uuucuaaugg uugugacuac     1380

guaagcaaua aaggaguaga uacaguauca gucggcaaca ccuuauacug uguaaacaaa     1440

caagaaggcc aaaguuuaua cgucaaagga gaacccauca ucaacuucua cgacccauua     1500

guauucccau cagacgaauu ugaugcaagc auuucacaag ucaacgaaaa aaucaaucaa     1560

ucauuagcau ucauccgaaa aucagacgaa uuauuacaca acguaaacgc cggaaaauca     1620

accacuaaua uaaugauaac cacaauaauc aucguaauaa uaguaauacu ucucucacua     1680

aucgcagucg gacuccuucu auacugcaaa gcaagaucua caccaguaac acuauccaaa     1740

gaucaacuaa guggcauaaa caacauagca uuuucuaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2542
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2542
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uaaaagccaa cgcgaucacc acaauccuga cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaagaguuc uaccaaucca caugcuccgc cgucuccaag      300

ggcuaccugg gcgcacuucg uacaggcugg uacaccuccg uaauaaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caagcaagaa      420

cuugacaaau acaaaaaugc agucaccgac cuucaacucc ucaugcaauc uacccccgcc      480

acaggcuccg gcuccgcuau cugcuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggugaaguaa acaaaauaaa auccgcccuc cucuccacca acaaagccgu cgucucccua      600

ucaaacggcg ucuccgugcu caccuucaag guucucgacc ugaaaaacua cauagacaaa      660

cagcuccuac caauccuuaa caaacagagc ugcuccauuc cgaauaucga aacgguaauc      720

gaauuucaac agaaaaacaa ccgccuccuc gaaauaacgc gagaguucuc cguaaacgcu      780

ggcgucacca cacccgucag caccuacaug cuaacgaacu ccgaacucuu gucgcucauc      840

aacgacaugc ccauaaccaa cgaccaaaag aaacuaaugu ccaauaacgu acaaaucgua      900

cgccaacaau cuuacuccau caugugcauc auaaaagaag aaguacuagc uuacgucguc      960

caacucccac uguacggagu caucgacacc cccugcugga aacuccacac cucuccccuc     1020

ugcaccacca acaccaaaga gggcuccaac auuugccuga cacgcaccga ccgcggcugg     1080

uacugcgaca acgcaggcuc cgucucguuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga agucaaucua     1200

ugcaacguag acaucuucaa cccgaaauau gacugcaaaa uuaugacauc uaaaaccgac     1260

guguccuccu cagucaucac uucccuagga gccaucguuu ccuguuacgg caagaccaaa     1320

ugcaccgcca gcaacaaaaa ccgaggcauc aucaaaaccu ucuccaacgg augugacuau     1380

gucuccaaca agggcgucga caccgucagc gucggcaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccucua cgucaaagga gagcccauaa ucaacuucua cgacccccuc     1500

gucuucccau ccgacgaguu cgacgccuca aucucccaag ucaacgagaa aaucaaccaa     1560

uccuuagccu ucauccguaa guccgacgaa cuccuucaca acgucaacgc cgguaaaucu     1620

accaccaaca ucaugauaac aacaauaauu aucgucauca ucgucauccu ccuuucccuc     1680

aucgcggucg ggcuauugcu cuacugcaaa gcccggucca ccccaguaac ccucucuaaa     1740

gaccaacuca gcggaaucaa uaacauagcc uucagcaauu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  2543
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2543
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2544
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2544
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      540

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1380

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1680

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2545
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2545
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2546
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2546
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      480

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      540

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      600

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      720

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      780

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      840

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua      900

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc      960

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg     1020

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1080

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1140

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1200

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1260

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1320

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1380

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1440

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1500

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1560

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1620

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1680

aaagaucaac ucucugggau aaacaauauc gcauucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2547
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2547
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2548
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2548
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      480

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      540

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      600

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      720

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      780

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      840

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug      900

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      960

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc     1020

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1080

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1140

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1200

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1260

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1320

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1380

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1440

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1500

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1620

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1680

aaagaucaac ucuccggaau uaacaauauc gcuuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2549
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2549
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac uuaccgccgu aacauuuugc      180

uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau caacaugcuc agcagucucc      240

aaaggauacc uuggagcauu aagaaccggc ugguauaccu ccguaauaac aauugaacua      300

ucuaauauaa aagaaaauaa auguaaugga acugacgcaa aaguuaaacu aauaaaacaa      360

gaacucgaca aauacaaaaa cgccgucaca gaccuacaac uacuaaugca aucaaccccc      420

gcaacaggau caggauccgc aaucugcagc ggcgucgcag uuugcaaagu ccuacauuua      480

gaaggagaag uaaacaaaau aaaaucugcu cuccucucua caaacaaagc aguaguguca      540

cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag accuaaaaaa uuacauagac      600

aaacaacuac uuccaauucu aaacaaacaa uccuguucca uacccaacau agaaacagua      660

auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua caagagaauu uuccgucaau      720

gcaggaguaa caaccccagu aucaaccuac auguuaacua acucagaacu cuuaucacua      780

auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca ugucaaauaa cguacaaaua      840

guccgacaac aaucauacuc caucaugugc auuauaaaag aagaaguacu agcauacguc      900

guccaauuac cacuauacgg cgucauagac acaccauguu ggaaacucca cacaucacca      960

cuaugcacua caaauacaaa agaaggcucc aacaucugcc uaacaagaac agacagaggu     1020

ugguauugcg acaacgcagg aucaguauca uuuuuccccc aagcagaaac auguaaagua     1080

caaucaaaua gagucuucug cgacaccaug aacucauuaa cacuaccuuc agaagucaac     1140

cuaugcaacg uagacaucuu caacccuaaa uaugacugca aaaucaugac cagcaaaacc     1200

gacguuucau cuuccguaau aacaucacua ggcgcaauag ucucauguua cggcaaaaca     1260

aaauguacag caucaaauaa aaaccgugga auaauaaaaa cauuuucuaa ugguugugac     1320

uacguaagca auaaaggagu agauacagua ucagucggca acaccuuaua cuguguaaac     1380

aaacaagaag gccaaaguuu auacgucaaa ggagaaccca ucaucaacuu cuacgaccca     1440

uuaguauucc caucagacga auuugaugca agcauuucac aagucaacga aaaaaucaau     1500

caaucauuag cauucauccg aaaaucagac gaauuauuac acaacguaaa cgccggaaaa     1560

ucaaccacua auauaaugau aaccacaaua aucaucguaa uaauaguaau acuucucuca     1620

cuaaucgcag ucggacuccu ucuauacugc aaagcaagau cuacaccagu aacacuaucc     1680

aaagaucaac uaaguggcau aaacaacaua gcauuuucua acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2550
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2550
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccuaaaagc caacgcgauc accacaaucc ugacagccgu caccuucugc      180

uucgccuccg gccaaaacau caccgaagag uucuaccaau ccacaugcuc cgccgucucc      240

aagggcuacc ugggcgcacu ucguacaggc ugguacaccu ccguaauaac caucgaacuc      300

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaagcaa      360

gaacuugaca aauacaaaaa ugcagucacc gaccuucaac uccucaugca aucuaccccc      420

gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg ucugcaaagu ccuccaccuc      480

gaaggugaag uaaacaaaau aaaauccgcc cuccucucca ccaacaaagc cgucgucucc      540

cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg accugaaaaa cuacauagac      600

aaacagcucc uaccaauccu uaacaaacag agcugcucca uuccgaauau cgaaacggua      660

aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa cgcgagaguu cuccguaaac      720

gcuggcguca ccacacccgu cagcaccuac augcuaacga acuccgaacu cuugucgcuc      780

aucaacgaca ugcccauaac caacgaccaa aagaaacuaa uguccaauaa cguacaaauc      840

guacgccaac aaucuuacuc caucaugugc aucauaaaag aagaaguacu agcuuacguc      900

guccaacucc cacuguacgg agucaucgac acccccugcu ggaaacucca caccucuccc      960

cucugcacca ccaacaccaa agagggcucc aacauuugcc ugacacgcac cgaccgcggc     1020

ugguacugcg acaacgcagg cuccgucucg uucuuccccc aagccgaaac cugcaaaguc     1080

caauccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaagucaau     1140

cuaugcaacg uagacaucuu caacccgaaa uaugacugca aaauuaugac aucuaaaacc     1200

gacguguccu ccucagucau cacuucccua ggagccaucg uuuccuguua cggcaagacc     1260

aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa ccuucuccaa cggaugugac     1320

uaugucucca acaagggcgu cgacaccguc agcgucggca acacccucua cugcgucaac     1380

aaacaagaag gccaaucccu cuacgucaaa ggagagccca uaaucaacuu cuacgacccc     1440

cucgucuucc cauccgacga guucgacgcc ucaaucuccc aagucaacga gaaaaucaac     1500

caauccuuag ccuucauccg uaaguccgac gaacuccuuc acaacgucaa cgccgguaaa     1560

ucuaccacca acaucaugau aacaacaaua auuaucguca ucaucgucau ccuccuuucc     1620

cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu ccaccccagu aacccucucu     1680

aaagaccaac ucagcggaau caauaacaua gccuucagca auuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  2551
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2551
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2552
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2552
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2553
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2553
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2554
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2554
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2555
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2555
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2556
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2556
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2557
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2557
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gcaaacgcaa uuacaacuau acuuaccgcc guaacauuuu gcuucgcauc ugggcaaaac      180

auuaccgaag aauuuuauca aucaacaugc ucagcagucu ccaaaggaua ccuuggagca      240

uuaagaaccg gcugguauac cuccguaaua acaauugaac uaucuaauau aaaagaaaau      300

aaauguaaug gaacugacgc aaaaguuaaa cuaauaaaac aagaacucga caaauacaaa      360

aacgccguca cagaccuaca acuacuaaug caaucaaccc ccgcaacagg aucaggaucc      420

gcaaucugca gcggcgucgc aguuugcaaa guccuacauu uagaaggaga aguaaacaaa      480

auaaaaucug cucuccucuc uacaaacaaa gcaguagugu cacuuucaaa cggaguauca      540

guucuaacau ucaaaguacu agaccuaaaa aauuacauag acaaacaacu acuuccaauu      600

cuaaacaaac aauccuguuc cauacccaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagac uccuagaaau uacaagagaa uuuuccguca augcaggagu aacaacccca      720

guaucaaccu acauguuaac uaacucagaa cucuuaucac uaauaaacga caugccaauc      780

acuaaugacc aaaaaaaacu caugucaaau aacguacaaa uaguccgaca acaaucauac      840

uccaucaugu gcauuauaaa agaagaagua cuagcauacg ucguccaauu accacuauac      900

ggcgucauag acacaccaug uuggaaacuc cacacaucac cacuaugcac uacaaauaca      960

aaagaaggcu ccaacaucug ccuaacaaga acagacagag guugguauug cgacaacgca     1020

ggaucaguau cauuuuuccc ccaagcagaa acauguaaag uacaaucaaa uagagucuuc     1080

ugcgacacca ugaacucauu aacacuaccu ucagaaguca accuaugcaa cguagacauc     1140

uucaacccua aauaugacug caaaaucaug accagcaaaa ccgacguuuc aucuuccgua     1200

auaacaucac uaggcgcaau agucucaugu uacggcaaaa caaaauguac agcaucaaau     1260

aaaaaccgug gaauaauaaa aacauuuucu aaugguugug acuacguaag caauaaagga     1320

guagauacag uaucagucgg caacaccuua uacuguguaa acaaacaaga aggccaaagu     1380

uuauacguca aaggagaacc caucaucaac uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug caagcauuuc acaagucaac gaaaaaauca aucaaucauu agcauucauc     1500

cgaaaaucag acgaauuauu acacaacgua aacgccggaa aaucaaccac uaauauaaug     1560

auaaccacaa uaaucaucgu aauaauagua auacuucucu cacuaaucgc agucggacuc     1620

cuucuauacu gcaaagcaag aucuacacca guaacacuau ccaaagauca acuaaguggc     1680

auaaacaaca uagcauuuuc uaacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2558
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2558
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuaaaa      120

gccaacgcga ucaccacaau ccugacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgaag aguucuacca auccacaugc uccgccgucu ccaagggcua ccugggcgca      240

cuucguacag gcugguacac cuccguaaua accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaagc aagaacuuga caaauacaaa      360

aaugcaguca ccgaccuuca acuccucaug caaucuaccc ccgccacagg cuccggcucc      420

gcuaucugcu ccggcgucgc cgucugcaaa guccuccacc ucgaagguga aguaaacaaa      480

auaaaauccg cccuccucuc caccaacaaa gccgucgucu cccuaucaaa cggcgucucc      540

gugcucaccu ucaagguucu cgaccugaaa aacuacauag acaaacagcu ccuaccaauc      600

cuuaacaaac agagcugcuc cauuccgaau aucgaaacgg uaaucgaauu ucaacagaaa      660

aacaaccgcc uccucgaaau aacgcgagag uucuccguaa acgcuggcgu caccacaccc      720

gucagcaccu acaugcuaac gaacuccgaa cucuugucgc ucaucaacga caugcccaua      780

accaacgacc aaaagaaacu aauguccaau aacguacaaa ucguacgcca acaaucuuac      840

uccaucaugu gcaucauaaa agaagaagua cuagcuuacg ucguccaacu cccacuguac      900

ggagucaucg acacccccug cuggaaacuc cacaccucuc cccucugcac caccaacacc      960

aaagagggcu ccaacauuug ccugacacgc accgaccgcg gcugguacug cgacaacgca     1020

ggcuccgucu cguucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgaaguca aucuaugcaa cguagacauc     1140

uucaacccga aauaugacug caaaauuaug acaucuaaaa ccgacguguc cuccucaguc     1200

aucacuuccc uaggagccau cguuuccugu uacggcaaga ccaaaugcac cgccagcaac     1260

aaaaaccgag gcaucaucaa aaccuucucc aacggaugug acuaugucuc caacaagggc     1320

gucgacaccg ucagcgucgg caacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cucuacguca aaggagagcc cauaaucaac uucuacgacc cccucgucuu cccauccgac     1440

gaguucgacg ccucaaucuc ccaagucaac gagaaaauca accaauccuu agccuucauc     1500

cguaaguccg acgaacuccu ucacaacguc aacgccggua aaucuaccac caacaucaug     1560

auaacaacaa uaauuaucgu caucaucguc auccuccuuu cccucaucgc ggucgggcua     1620

uugcucuacu gcaaagcccg guccacccca guaacccucu cuaaagacca acucagcgga     1680

aucaauaaca uagccuucag caauuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  2559
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2559
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2560
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2560
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2561
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2561
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2562
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2562
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2563
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2563
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2564
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2564
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2565
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2565
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gcaaacgcaa uuacaacuau acuuaccgcc      120

guaacauuuu gcuucgcauc ugggcaaaac auuaccgaag aauuuuauca aucaacaugc      180

ucagcagucu ccaaaggaua ccuuggagca uuaagaaccg gcugguauac cuccguaaua      240

acaauugaac uaucuaauau aaaagaaaau aaauguaaug gaacugacgc aaaaguuaaa      300

cuaauaaaac aagaacucga caaauacaaa aacgccguca cagaccuaca acuacuaaug      360

caaucaaccc ccgcaacagg aucaggaucc gcaaucugca gcggcgucgc aguuugcaaa      420

guccuacauu uagaaggaga aguaaacaaa auaaaaucug cucuccucuc uacaaacaaa      480

gcaguagugu cacuuucaaa cggaguauca guucuaacau ucaaaguacu agaccuaaaa      540

aauuacauag acaaacaacu acuuccaauu cuaaacaaac aauccuguuc cauacccaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagac uccuagaaau uacaagagaa      660

uuuuccguca augcaggagu aacaacccca guaucaaccu acauguuaac uaacucagaa      720

cucuuaucac uaauaaacga caugccaauc acuaaugacc aaaaaaaacu caugucaaau      780

aacguacaaa uaguccgaca acaaucauac uccaucaugu gcauuauaaa agaagaagua      840

cuagcauacg ucguccaauu accacuauac ggcgucauag acacaccaug uuggaaacuc      900

cacacaucac cacuaugcac uacaaauaca aaagaaggcu ccaacaucug ccuaacaaga      960

acagacagag guugguauug cgacaacgca ggaucaguau cauuuuuccc ccaagcagaa     1020

acauguaaag uacaaucaaa uagagucuuc ugcgacacca ugaacucauu aacacuaccu     1080

ucagaaguca accuaugcaa cguagacauc uucaacccua aauaugacug caaaaucaug     1140

accagcaaaa ccgacguuuc aucuuccgua auaacaucac uaggcgcaau agucucaugu     1200

uacggcaaaa caaaauguac agcaucaaau aaaaaccgug gaauaauaaa aacauuuucu     1260

aaugguugug acuacguaag caauaaagga guagauacag uaucagucgg caacaccuua     1320

uacuguguaa acaaacaaga aggccaaagu uuauacguca aaggagaacc caucaucaac     1380

uucuacgacc cauuaguauu cccaucagac gaauuugaug caagcauuuc acaagucaac     1440

gaaaaaauca aucaaucauu agcauucauc cgaaaaucag acgaauuauu acacaacgua     1500

aacgccggaa aaucaaccac uaauauaaug auaaccacaa uaaucaucgu aauaauagua     1560

auacuucucu cacuaaucgc agucggacuc cuucuauacu gcaaagcaag aucuacacca     1620

guaacacuau ccaaagauca acuaaguggc auaaacaaca uagcauuuuc uaacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2566
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2566
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuaaaa gccaacgcga ucaccacaau ccugacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaagggcua ccugggcgca cuucguacag gcugguacac cuccguaaua      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaagc aagaacuuga caaauacaaa aaugcaguca ccgaccuuca acuccucaug      360

caaucuaccc ccgccacagg cuccggcucc gcuaucugcu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaagguga aguaaacaaa auaaaauccg cccuccucuc caccaacaaa      480

gccgucgucu cccuaucaaa cggcgucucc gugcucaccu ucaagguucu cgaccugaaa      540

aacuacauag acaaacagcu ccuaccaauc cuuaacaaac agagcugcuc cauuccgaau      600

aucgaaacgg uaaucgaauu ucaacagaaa aacaaccgcc uccucgaaau aacgcgagag      660

uucuccguaa acgcuggcgu caccacaccc gucagcaccu acaugcuaac gaacuccgaa      720

cucuugucgc ucaucaacga caugcccaua accaacgacc aaaagaaacu aauguccaau      780

aacguacaaa ucguacgcca acaaucuuac uccaucaugu gcaucauaaa agaagaagua      840

cuagcuuacg ucguccaacu cccacuguac ggagucaucg acacccccug cuggaaacuc      900

cacaccucuc cccucugcac caccaacacc aaagagggcu ccaacauuug ccugacacgc      960

accgaccgcg gcugguacug cgacaacgca ggcuccgucu cguucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgaaguca aucuaugcaa cguagacauc uucaacccga aauaugacug caaaauuaug     1140

acaucuaaaa ccgacguguc cuccucaguc aucacuuccc uaggagccau cguuuccugu     1200

uacggcaaga ccaaaugcac cgccagcaac aaaaaccgag gcaucaucaa aaccuucucc     1260

aacggaugug acuaugucuc caacaagggc gucgacaccg ucagcgucgg caacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cucuacguca aaggagagcc cauaaucaac     1380

uucuacgacc cccucgucuu cccauccgac gaguucgacg ccucaaucuc ccaagucaac     1440

gagaaaauca accaauccuu agccuucauc cguaaguccg acgaacuccu ucacaacguc     1500

aacgccggua aaucuaccac caacaucaug auaacaacaa uaauuaucgu caucaucguc     1560

auccuccuuu cccucaucgc ggucgggcua uugcucuacu gcaaagcccg guccacccca     1620

guaacccucu cuaaagacca acucagcgga aucaauaaca uagccuucag caauuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  2567
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2567
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2568
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2568
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2569
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2569
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2570
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2570
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2571
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2571
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2572
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2572
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2573
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2573
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagcaaac gcaauuacaa cuauacuuac cgccguaaca      180

uuuugcuucg caucugggca aaacauuacc gaagaauuuu aucaaucaac augcucagca      240

gucuccaaag gauaccuugg agcauuaaga accggcuggu auaccuccgu aauaacaauu      300

gaacuaucua auauaaaaga aaauaaaugu aauggaacug acgcaaaagu uaaacuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagacc uacaacuacu aaugcaauca      420

acccccgcaa caggaucagg auccgcaauc ugcagcggcg ucgcaguuug caaaguccua      480

cauuuagaag gagaaguaaa caaaauaaaa ucugcucucc ucucuacaaa caaagcagua      540

gugucacuuu caaacggagu aucaguucua acauucaaag uacuagaccu aaaaaauuac      600

auagacaaac aacuacuucc aauucuaaac aaacaauccu guuccauacc caacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agacuccuag aaauuacaag agaauuuucc      720

gucaaugcag gaguaacaac cccaguauca accuacaugu uaacuaacuc agaacucuua      780

ucacuaauaa acgacaugcc aaucacuaau gaccaaaaaa aacucauguc aaauaacgua      840

caaauagucc gacaacaauc auacuccauc augugcauua uaaaagaaga aguacuagca      900

uacgucgucc aauuaccacu auacggcguc auagacacac cauguuggaa acuccacaca      960

ucaccacuau gcacuacaaa uacaaaagaa ggcuccaaca ucugccuaac aagaacagac     1020

agagguuggu auugcgacaa cgcaggauca guaucauuuu ucccccaagc agaaacaugu     1080

aaaguacaau caaauagagu cuucugcgac accaugaacu cauuaacacu accuucagaa     1140

gucaaccuau gcaacguaga caucuucaac ccuaaauaug acugcaaaau caugaccagc     1200

aaaaccgacg uuucaucuuc cguaauaaca ucacuaggcg caauagucuc auguuacggc     1260

aaaacaaaau guacagcauc aaauaaaaac cguggaauaa uaaaaacauu uucuaauggu     1320

ugugacuacg uaagcaauaa aggaguagau acaguaucag ucggcaacac cuuauacugu     1380

guaaacaaac aagaaggcca aaguuuauac gucaaaggag aacccaucau caacuucuac     1440

gacccauuag uauucccauc agacgaauuu gaugcaagca uuucacaagu caacgaaaaa     1500

aucaaucaau cauuagcauu cauccgaaaa ucagacgaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa ccacuaauau aaugauaacc acaauaauca ucguaauaau aguaauacuu     1620

cucucacuaa ucgcagucgg acuccuucua uacugcaaag caagaucuac accaguaaca     1680

cuauccaaag aucaacuaag uggcauaaac aacauagcau uuucuaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2574
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2574
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu aaaagccaac gcgaucacca caauccugac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaagaguucu accaauccac augcuccgcc      240

gucuccaagg gcuaccuggg cgcacuucgu acaggcuggu acaccuccgu aauaaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aagcaagaac uugacaaaua caaaaaugca gucaccgacc uucaacuccu caugcaaucu      420

acccccgcca caggcuccgg cuccgcuauc ugcuccggcg ucgccgucug caaaguccuc      480

caccucgaag gugaaguaaa caaaauaaaa uccgcccucc ucuccaccaa caaagccguc      540

gucucccuau caaacggcgu cuccgugcuc accuucaagg uucucgaccu gaaaaacuac      600

auagacaaac agcuccuacc aauccuuaac aaacagagcu gcuccauucc gaauaucgaa      660

acgguaaucg aauuucaaca gaaaaacaac cgccuccucg aaauaacgcg agaguucucc      720

guaaacgcug gcgucaccac acccgucagc accuacaugc uaacgaacuc cgaacucuug      780

ucgcucauca acgacaugcc cauaaccaac gaccaaaaga aacuaauguc caauaacgua      840

caaaucguac gccaacaauc uuacuccauc augugcauca uaaaagaaga aguacuagcu      900

uacgucgucc aacucccacu guacggaguc aucgacaccc ccugcuggaa acuccacacc      960

ucuccccucu gcaccaccaa caccaaagag ggcuccaaca uuugccugac acgcaccgac     1020

cgcggcuggu acugcgacaa cgcaggcucc gucucguucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgaa     1140

gucaaucuau gcaacguaga caucuucaac ccgaaauaug acugcaaaau uaugacaucu     1200

aaaaccgacg uguccuccuc agucaucacu ucccuaggag ccaucguuuc cuguuacggc     1260

aagaccaaau gcaccgccag caacaaaaac cgaggcauca ucaaaaccuu cuccaacgga     1320

ugugacuaug ucuccaacaa gggcgucgac accgucagcg ucggcaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccucuac gucaaaggag agcccauaau caacuucuac     1440

gacccccucg ucuucccauc cgacgaguuc gacgccucaa ucucccaagu caacgagaaa     1500

aucaaccaau ccuuagccuu cauccguaag uccgacgaac uccuucacaa cgucaacgcc     1560

gguaaaucua ccaccaacau caugauaaca acaauaauua ucgucaucau cgucauccuc     1620

cuuucccuca ucgcggucgg gcuauugcuc uacugcaaag cccgguccac cccaguaacc     1680

cucucuaaag accaacucag cggaaucaau aacauagccu ucagcaauua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2575
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2575
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2576
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2576
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2577
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2577
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2578
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2578
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2579
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2579
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2580
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2580
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2581
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2581
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agcaaacgca      120

auuacaacua uacuuaccgc cguaacauuu ugcuucgcau cugggcaaaa cauuaccgaa      180

gaauuuuauc aaucaacaug cucagcaguc uccaaaggau accuuggagc auuaagaacc      240

ggcugguaua ccuccguaau aacaauugaa cuaucuaaua uaaaagaaaa uaaauguaau      300

ggaacugacg caaaaguuaa acuaauaaaa caagaacucg acaaauacaa aaacgccguc      360

acagaccuac aacuacuaau gcaaucaacc cccgcaacag gaucaggauc cgcaaucugc      420

agcggcgucg caguuugcaa aguccuacau uuagaaggag aaguaaacaa aauaaaaucu      480

gcucuccucu cuacaaacaa agcaguagug ucacuuucaa acggaguauc aguucuaaca      540

uucaaaguac uagaccuaaa aaauuacaua gacaaacaac uacuuccaau ucuaaacaaa      600

caauccuguu ccauacccaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

cuccuagaaa uuacaagaga auuuuccguc aaugcaggag uaacaacccc aguaucaacc      720

uacauguuaa cuaacucaga acucuuauca cuaauaaacg acaugccaau cacuaaugac      780

caaaaaaaac ucaugucaaa uaacguacaa auaguccgac aacaaucaua cuccaucaug      840

ugcauuauaa aagaagaagu acuagcauac gucguccaau uaccacuaua cggcgucaua      900

gacacaccau guuggaaacu ccacacauca ccacuaugca cuacaaauac aaaagaaggc      960

uccaacaucu gccuaacaag aacagacaga gguugguauu gcgacaacgc aggaucagua     1020

ucauuuuucc cccaagcaga aacauguaaa guacaaucaa auagagucuu cugcgacacc     1080

augaacucau uaacacuacc uucagaaguc aaccuaugca acguagacau cuucaacccu     1140

aaauaugacu gcaaaaucau gaccagcaaa accgacguuu caucuuccgu aauaacauca     1200

cuaggcgcaa uagucucaug uuacggcaaa acaaaaugua cagcaucaaa uaaaaaccgu     1260

ggaauaauaa aaacauuuuc uaaugguugu gacuacguaa gcaauaaagg aguagauaca     1320

guaucagucg gcaacaccuu auacugugua aacaaacaag aaggccaaag uuuauacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccauuaguau ucccaucaga cgaauuugau     1440

gcaagcauuu cacaagucaa cgaaaaaauc aaucaaucau uagcauucau ccgaaaauca     1500

gacgaauuau uacacaacgu aaacgccgga aaaucaacca cuaauauaau gauaaccaca     1560

auaaucaucg uaauaauagu aauacuucuc ucacuaaucg cagucggacu ccuucuauac     1620

ugcaaagcaa gaucuacacc aguaacacua uccaaagauc aacuaagugg cauaaacaac     1680

auagcauuuu cuaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2582
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2582
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuaaa agccaacgcg      120

aucaccacaa uccugacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaagggcu accugggcgc acuucguaca      240

ggcugguaca ccuccguaau aaccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaag caagaacuug acaaauacaa aaaugcaguc      360

accgaccuuc aacuccucau gcaaucuacc cccgccacag gcuccggcuc cgcuaucugc      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggug aaguaaacaa aauaaaaucc      480

gcccuccucu ccaccaacaa agccgucguc ucccuaucaa acggcgucuc cgugcucacc      540

uucaagguuc ucgaccugaa aaacuacaua gacaaacagc uccuaccaau ccuuaacaaa      600

cagagcugcu ccauuccgaa uaucgaaacg guaaucgaau uucaacagaa aaacaaccgc      660

cuccucgaaa uaacgcgaga guucuccgua aacgcuggcg ucaccacacc cgucagcacc      720

uacaugcuaa cgaacuccga acucuugucg cucaucaacg acaugcccau aaccaacgac      780

caaaagaaac uaauguccaa uaacguacaa aucguacgcc aacaaucuua cuccaucaug      840

ugcaucauaa aagaagaagu acuagcuuac gucguccaac ucccacugua cggagucauc      900

gacacccccu gcuggaaacu ccacaccucu ccccucugca ccaccaacac caaagagggc      960

uccaacauuu gccugacacg caccgaccgc ggcugguacu gcgacaacgc aggcuccguc     1020

ucguucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgaaguc aaucuaugca acguagacau cuucaacccg     1140

aaauaugacu gcaaaauuau gacaucuaaa accgacgugu ccuccucagu caucacuucc     1200

cuaggagcca ucguuuccug uuacggcaag accaaaugca ccgccagcaa caaaaaccga     1260

ggcaucauca aaaccuucuc caacggaugu gacuaugucu ccaacaaggg cgucgacacc     1320

gucagcgucg gcaacacccu cuacugcguc aacaaacaag aaggccaauc ccucuacguc     1380

aaaggagagc ccauaaucaa cuucuacgac ccccucgucu ucccauccga cgaguucgac     1440

gccucaaucu cccaagucaa cgagaaaauc aaccaauccu uagccuucau ccguaagucc     1500

gacgaacucc uucacaacgu caacgccggu aaaucuacca ccaacaucau gauaacaaca     1560

auaauuaucg ucaucaucgu cauccuccuu ucccucaucg cggucgggcu auugcucuac     1620

ugcaaagccc gguccacccc aguaacccuc ucuaaagacc aacucagcgg aaucaauaac     1680

auagccuuca gcaauuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2583
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2583
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2584
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2584
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2585
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2585
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2586
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2586
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2587
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2587
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2588
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2588
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2589
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2589
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agcaaacgca      120

auuacaacua uacuuaccgc cguaacauuu ugcuucgcau cugggcaaaa cauuaccgaa      180

gaauuuuauc aaucaacaug cucagcaguc uccaaaggau accuuggagc auuaagaacc      240

ggcugguaua ccuccguaau aacaauugaa cuaucuaaua uaaaagaaaa uaaauguaau      300

ggaacugacg caaaaguuaa acuaauaaaa caagaacucg acaaauacaa aaacgccguc      360

acagaccuac aacuacuaau gcaaucaacc cccgcaacag gaucaggauc cgcaaucugc      420

agcggcgucg caguuugcaa aguccuacau uuagaaggag aaguaaacaa aauaaaaucu      480

gcucuccucu cuacaaacaa agcaguagug ucacuuucaa acggaguauc aguucuaaca      540

uucaaaguac uagaccuaaa aaauuacaua gacaaacaac uacuuccaau ucuaaacaaa      600

caauccuguu ccauacccaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

cuccuagaaa uuacaagaga auuuuccguc aaugcaggag uaacaacccc aguaucaacc      720

uacauguuaa cuaacucaga acucuuauca cuaauaaacg acaugccaau cacuaaugac      780

caaaaaaaac ucaugucaaa uaacguacaa auaguccgac aacaaucaua cuccaucaug      840

ugcauuauaa aagaagaagu acuagcauac gucguccaau uaccacuaua cggcgucaua      900

gacacaccau guuggaaacu ccacacauca ccacuaugca cuacaaauac aaaagaaggc      960

uccaacaucu gccuaacaag aacagacaga gguugguauu gcgacaacgc aggaucagua     1020

ucauuuuucc cccaagcaga aacauguaaa guacaaucaa auagagucuu cugcgacacc     1080

augaacucau uaacacuacc uucagaaguc aaccuaugca acguagacau cuucaacccu     1140

aaauaugacu gcaaaaucau gaccagcaaa accgacguuu caucuuccgu aauaacauca     1200

cuaggcgcaa uagucucaug uuacggcaaa acaaaaugua cagcaucaaa uaaaaaccgu     1260

ggaauaauaa aaacauuuuc uaaugguugu gacuacguaa gcaauaaagg aguagauaca     1320

guaucagucg gcaacaccuu auacugugua aacaaacaag aaggccaaag uuuauacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccauuaguau ucccaucaga cgaauuugau     1440

gcaagcauuu cacaagucaa cgaaaaaauc aaucaaucau uagcauucau ccgaaaauca     1500

gacgaauuau uacacaacgu aaacgccgga aaaucaacca cuaauauaau gauaaccaca     1560

auaaucaucg uaauaauagu aauacuucuc ucacuaaucg cagucggacu ccuucuauac     1620

ugcaaagcaa gaucuacacc aguaacacua uccaaagauc aacuaagugg cauaaacaac     1680

auagcauuuu cuaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2590
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2590
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuaaa agccaacgcg      120

aucaccacaa uccugacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaagggcu accugggcgc acuucguaca      240

ggcugguaca ccuccguaau aaccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaag caagaacuug acaaauacaa aaaugcaguc      360

accgaccuuc aacuccucau gcaaucuacc cccgccacag gcuccggcuc cgcuaucugc      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggug aaguaaacaa aauaaaaucc      480

gcccuccucu ccaccaacaa agccgucguc ucccuaucaa acggcgucuc cgugcucacc      540

uucaagguuc ucgaccugaa aaacuacaua gacaaacagc uccuaccaau ccuuaacaaa      600

cagagcugcu ccauuccgaa uaucgaaacg guaaucgaau uucaacagaa aaacaaccgc      660

cuccucgaaa uaacgcgaga guucuccgua aacgcuggcg ucaccacacc cgucagcacc      720

uacaugcuaa cgaacuccga acucuugucg cucaucaacg acaugcccau aaccaacgac      780

caaaagaaac uaauguccaa uaacguacaa aucguacgcc aacaaucuua cuccaucaug      840

ugcaucauaa aagaagaagu acuagcuuac gucguccaac ucccacugua cggagucauc      900

gacacccccu gcuggaaacu ccacaccucu ccccucugca ccaccaacac caaagagggc      960

uccaacauuu gccugacacg caccgaccgc ggcugguacu gcgacaacgc aggcuccguc     1020

ucguucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgaaguc aaucuaugca acguagacau cuucaacccg     1140

aaauaugacu gcaaaauuau gacaucuaaa accgacgugu ccuccucagu caucacuucc     1200

cuaggagcca ucguuuccug uuacggcaag accaaaugca ccgccagcaa caaaaaccga     1260

ggcaucauca aaaccuucuc caacggaugu gacuaugucu ccaacaaggg cgucgacacc     1320

gucagcgucg gcaacacccu cuacugcguc aacaaacaag aaggccaauc ccucuacguc     1380

aaaggagagc ccauaaucaa cuucuacgac ccccucgucu ucccauccga cgaguucgac     1440

gccucaaucu cccaagucaa cgagaaaauc aaccaauccu uagccuucau ccguaagucc     1500

gacgaacucc uucacaacgu caacgccggu aaaucuacca ccaacaucau gauaacaaca     1560

auaauuaucg ucaucaucgu cauccuccuu ucccucaucg cggucgggcu auugcucuac     1620

ugcaaagccc gguccacccc aguaacccuc ucuaaagacc aacucagcgg aaucaauaac     1680

auagccuuca gcaauuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  2591
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2591
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2592
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2592
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2593
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2593
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2594
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2594
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2595
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2595
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2596
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2596
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2597
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2597
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agcaaacgca      120

auuacaacua uacuuaccgc cguaacauuu ugcuucgcau cugggcaaaa cauuaccgaa      180

gaauuuuauc aaucaacaug cucagcaguc uccaaaggau accuuggagc auuaagaacc      240

ggcugguaua ccuccguaau aacaauugaa cuaucuaaua uaaaagaaaa uaaauguaau      300

ggaacugacg caaaaguuaa acuaauaaaa caagaacucg acaaauacaa aaacgccguc      360

acagaccuac aacuacuaau gcaaucaacc cccgcaacag gaucaggauc cgcaaucugc      420

agcggcgucg caguuugcaa aguccuacau uuagaaggag aaguaaacaa aauaaaaucu      480

gcucuccucu cuacaaacaa agcaguagug ucacuuucaa acggaguauc aguucuaaca      540

uucaaaguac uagaccuaaa aaauuacaua gacaaacaac uacuuccaau ucuaaacaaa      600

caauccuguu ccauacccaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

cuccuagaaa uuacaagaga auuuuccguc aaugcaggag uaacaacccc aguaucaacc      720

uacauguuaa cuaacucaga acucuuauca cuaauaaacg acaugccaau cacuaaugac      780

caaaaaaaac ucaugucaaa uaacguacaa auaguccgac aacaaucaua cuccaucaug      840

ugcauuauaa aagaagaagu acuagcauac gucguccaau uaccacuaua cggcgucaua      900

gacacaccau guuggaaacu ccacacauca ccacuaugca cuacaaauac aaaagaaggc      960

uccaacaucu gccuaacaag aacagacaga gguugguauu gcgacaacgc aggaucagua     1020

ucauuuuucc cccaagcaga aacauguaaa guacaaucaa auagagucuu cugcgacacc     1080

augaacucau uaacacuacc uucagaaguc aaccuaugca acguagacau cuucaacccu     1140

aaauaugacu gcaaaaucau gaccagcaaa accgacguuu caucuuccgu aauaacauca     1200

cuaggcgcaa uagucucaug uuacggcaaa acaaaaugua cagcaucaaa uaaaaaccgu     1260

ggaauaauaa aaacauuuuc uaaugguugu gacuacguaa gcaauaaagg aguagauaca     1320

guaucagucg gcaacaccuu auacugugua aacaaacaag aaggccaaag uuuauacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccauuaguau ucccaucaga cgaauuugau     1440

gcaagcauuu cacaagucaa cgaaaaaauc aaucaaucau uagcauucau ccgaaaauca     1500

gacgaauuau uacacaacgu aaacgccgga aaaucaacca cuaauauaau gauaaccaca     1560

auaaucaucg uaauaauagu aauacuucuc ucacuaaucg cagucggacu ccuucuauac     1620

ugcaaagcaa gaucuacacc aguaacacua uccaaagauc aacuaagugg cauaaacaac     1680

auagcauuuu cuaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2598
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2598
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuaaa agccaacgcg      120

aucaccacaa uccugacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaagggcu accugggcgc acuucguaca      240

ggcugguaca ccuccguaau aaccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaag caagaacuug acaaauacaa aaaugcaguc      360

accgaccuuc aacuccucau gcaaucuacc cccgccacag gcuccggcuc cgcuaucugc      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggug aaguaaacaa aauaaaaucc      480

gcccuccucu ccaccaacaa agccgucguc ucccuaucaa acggcgucuc cgugcucacc      540

uucaagguuc ucgaccugaa aaacuacaua gacaaacagc uccuaccaau ccuuaacaaa      600

cagagcugcu ccauuccgaa uaucgaaacg guaaucgaau uucaacagaa aaacaaccgc      660

cuccucgaaa uaacgcgaga guucuccgua aacgcuggcg ucaccacacc cgucagcacc      720

uacaugcuaa cgaacuccga acucuugucg cucaucaacg acaugcccau aaccaacgac      780

caaaagaaac uaauguccaa uaacguacaa aucguacgcc aacaaucuua cuccaucaug      840

ugcaucauaa aagaagaagu acuagcuuac gucguccaac ucccacugua cggagucauc      900

gacacccccu gcuggaaacu ccacaccucu ccccucugca ccaccaacac caaagagggc      960

uccaacauuu gccugacacg caccgaccgc ggcugguacu gcgacaacgc aggcuccguc     1020

ucguucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgaaguc aaucuaugca acguagacau cuucaacccg     1140

aaauaugacu gcaaaauuau gacaucuaaa accgacgugu ccuccucagu caucacuucc     1200

cuaggagcca ucguuuccug uuacggcaag accaaaugca ccgccagcaa caaaaaccga     1260

ggcaucauca aaaccuucuc caacggaugu gacuaugucu ccaacaaggg cgucgacacc     1320

gucagcgucg gcaacacccu cuacugcguc aacaaacaag aaggccaauc ccucuacguc     1380

aaaggagagc ccauaaucaa cuucuacgac ccccucgucu ucccauccga cgaguucgac     1440

gccucaaucu cccaagucaa cgagaaaauc aaccaauccu uagccuucau ccguaagucc     1500

gacgaacucc uucacaacgu caacgccggu aaaucuacca ccaacaucau gauaacaaca     1560

auaauuaucg ucaucaucgu cauccuccuu ucccucaucg cggucgggcu auugcucuac     1620

ugcaaagccc gguccacccc aguaacccuc ucuaaagacc aacucagcgg aaucaauaac     1680

auagccuuca gcaauuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  2599
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2599
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2600
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2600
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2601
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2601
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2602
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2602
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gauaaacaau     1680

aucgcauuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2603
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2603
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2604
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2604
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aauuaacaau     1680

aucgcuuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2605
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2605
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccuaaa agcaaacgca      120

auuacaacua uacuuaccgc cguaacauuu ugcuucgcau cugggcaaaa cauuaccgaa      180

gaauuuuauc aaucaacaug cucagcaguc uccaaaggau accuuggagc auuaagaacc      240

ggcugguaua ccuccguaau aacaauugaa cuaucuaaua uaaaagaaaa uaaauguaau      300

ggaacugacg caaaaguuaa acuaauaaaa caagaacucg acaaauacaa aaacgccguc      360

acagaccuac aacuacuaau gcaaucaacc cccgcaacag gaucaggauc cgcaaucugc      420

agcggcgucg caguuugcaa aguccuacau uuagaaggag aaguaaacaa aauaaaaucu      480

gcucuccucu cuacaaacaa agcaguagug ucacuuucaa acggaguauc aguucuaaca      540

uucaaaguac uagaccuaaa aaauuacaua gacaaacaac uacuuccaau ucuaaacaaa      600

caauccuguu ccauacccaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

cuccuagaaa uuacaagaga auuuuccguc aaugcaggag uaacaacccc aguaucaacc      720

uacauguuaa cuaacucaga acucuuauca cuaauaaacg acaugccaau cacuaaugac      780

caaaaaaaac ucaugucaaa uaacguacaa auaguccgac aacaaucaua cuccaucaug      840

ugcauuauaa aagaagaagu acuagcauac gucguccaau uaccacuaua cggcgucaua      900

gacacaccau guuggaaacu ccacacauca ccacuaugca cuacaaauac aaaagaaggc      960

uccaacaucu gccuaacaag aacagacaga gguugguauu gcgacaacgc aggaucagua     1020

ucauuuuucc cccaagcaga aacauguaaa guacaaucaa auagagucuu cugcgacacc     1080

augaacucau uaacacuacc uucagaaguc aaccuaugca acguagacau cuucaacccu     1140

aaauaugacu gcaaaaucau gaccagcaaa accgacguuu caucuuccgu aauaacauca     1200

cuaggcgcaa uagucucaug uuacggcaaa acaaaaugua cagcaucaaa uaaaaaccgu     1260

ggaauaauaa aaacauuuuc uaaugguugu gacuacguaa gcaauaaagg aguagauaca     1320

guaucagucg gcaacaccuu auacugugua aacaaacaag aaggccaaag uuuauacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccauuaguau ucccaucaga cgaauuugau     1440

gcaagcauuu cacaagucaa cgaaaaaauc aaucaaucau uagcauucau ccgaaaauca     1500

gacgaauuau uacacaacgu aaacgccgga aaaucaacca cuaauauaau gauaaccaca     1560

auaaucaucg uaauaauagu aauacuucuc ucacuaaucg cagucggacu ccuucuauac     1620

ugcaaagcaa gaucuacacc aguaacacua uccaaagauc aacuaagugg cauaaacaac     1680

auagcauuuu cuaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2606
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2606
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuaaa agccaacgcg      120

aucaccacaa uccugacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaagggcu accugggcgc acuucguaca      240

ggcugguaca ccuccguaau aaccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaag caagaacuug acaaauacaa aaaugcaguc      360

accgaccuuc aacuccucau gcaaucuacc cccgccacag gcuccggcuc cgcuaucugc      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggug aaguaaacaa aauaaaaucc      480

gcccuccucu ccaccaacaa agccgucguc ucccuaucaa acggcgucuc cgugcucacc      540

uucaagguuc ucgaccugaa aaacuacaua gacaaacagc uccuaccaau ccuuaacaaa      600

cagagcugcu ccauuccgaa uaucgaaacg guaaucgaau uucaacagaa aaacaaccgc      660

cuccucgaaa uaacgcgaga guucuccgua aacgcuggcg ucaccacacc cgucagcacc      720

uacaugcuaa cgaacuccga acucuugucg cucaucaacg acaugcccau aaccaacgac      780

caaaagaaac uaauguccaa uaacguacaa aucguacgcc aacaaucuua cuccaucaug      840

ugcaucauaa aagaagaagu acuagcuuac gucguccaac ucccacugua cggagucauc      900

gacacccccu gcuggaaacu ccacaccucu ccccucugca ccaccaacac caaagagggc      960

uccaacauuu gccugacacg caccgaccgc ggcugguacu gcgacaacgc aggcuccguc     1020

ucguucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgaaguc aaucuaugca acguagacau cuucaacccg     1140

aaauaugacu gcaaaauuau gacaucuaaa accgacgugu ccuccucagu caucacuucc     1200

cuaggagcca ucguuuccug uuacggcaag accaaaugca ccgccagcaa caaaaaccga     1260

ggcaucauca aaaccuucuc caacggaugu gacuaugucu ccaacaaggg cgucgacacc     1320

gucagcgucg gcaacacccu cuacugcguc aacaaacaag aaggccaauc ccucuacguc     1380

aaaggagagc ccauaaucaa cuucuacgac ccccucgucu ucccauccga cgaguucgac     1440

gccucaaucu cccaagucaa cgagaaaauc aaccaauccu uagccuucau ccguaagucc     1500

gacgaacucc uucacaacgu caacgccggu aaaucuacca ccaacaucau gauaacaaca     1560

auaauuaucg ucaucaucgu cauccuccuu ucccucaucg cggucgggcu auugcucuac     1620

ugcaaagccc gguccacccc aguaacccuc ucuaaagacc aacucagcgg aaucaauaac     1680

auagccuuca gcaauuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  2607
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2607
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2608
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2608
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2609
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2609
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2610
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2610
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2611
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2611
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2612
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2612
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2613
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2613
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac      120

uuaccgccgu aacauuuugc uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau      180

caacaugcuc agcagucucc aaaggauacc uuggagcauu aagaaccggc ugguauaccu      240

ccguaauaac aauugaacua ucuaauauaa aagaaaauaa auguaaugga acugacgcaa      300

aaguuaaacu aauaaaacaa gaacucgaca aauacaaaaa cgccgucaca gaccuacaac      360

uacuaaugca aucaaccccc gcaacaggau caggauccgc aaucugcagc ggcgucgcag      420

uuugcaaagu ccuacauuua gaaggagaag uaaacaaaau aaaaucugcu cuccucucua      480

caaacaaagc aguaguguca cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag      540

accuaaaaaa uuacauagac aaacaacuac uuccaauucu aaacaaacaa uccuguucca      600

uacccaacau agaaacagua auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua      660

caagagaauu uuccgucaau gcaggaguaa caaccccagu aucaaccuac auguuaacua      720

acucagaacu cuuaucacua auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca      780

ugucaaauaa cguacaaaua guccgacaac aaucauacuc caucaugugc auuauaaaag      840

aagaaguacu agcauacguc guccaauuac cacuauacgg cgucauagac acaccauguu      900

ggaaacucca cacaucacca cuaugcacua caaauacaaa agaaggcucc aacaucugcc      960

uaacaagaac agacagaggu ugguauugcg acaacgcagg aucaguauca uuuuuccccc     1020

aagcagaaac auguaaagua caaucaaaua gagucuucug cgacaccaug aacucauuaa     1080

cacuaccuuc agaagucaac cuaugcaacg uagacaucuu caacccuaaa uaugacugca     1140

aaaucaugac cagcaaaacc gacguuucau cuuccguaau aacaucacua ggcgcaauag     1200

ucucauguua cggcaaaaca aaauguacag caucaaauaa aaaccgugga auaauaaaaa     1260

cauuuucuaa ugguugugac uacguaagca auaaaggagu agauacagua ucagucggca     1320

acaccuuaua cuguguaaac aaacaagaag gccaaaguuu auacgucaaa ggagaaccca     1380

ucaucaacuu cuacgaccca uuaguauucc caucagacga auuugaugca agcauuucac     1440

aagucaacga aaaaaucaau caaucauuag cauucauccg aaaaucagac gaauuauuac     1500

acaacguaaa cgccggaaaa ucaaccacua auauaaugau aaccacaaua aucaucguaa     1560

uaauaguaau acuucucuca cuaaucgcag ucggacuccu ucuauacugc aaagcaagau     1620

cuacaccagu aacacuaucc aaagaucaac uaaguggcau aaacaacaua gcauuuucua     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2614
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2614
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuaaaagc caacgcgauc accacaaucc      120

ugacagccgu caccuucugc uucgccuccg gccaaaacau caccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aagggcuacc ugggcgcacu ucguacaggc ugguacaccu      240

ccguaauaac caucgaacuc uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaagcaa gaacuugaca aauacaaaaa ugcagucacc gaccuucaac      360

uccucaugca aucuaccccc gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggugaag uaaacaaaau aaaauccgcc cuccucucca      480

ccaacaaagc cgucgucucc cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg      540

accugaaaaa cuacauagac aaacagcucc uaccaauccu uaacaaacag agcugcucca      600

uuccgaauau cgaaacggua aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa      660

cgcgagaguu cuccguaaac gcuggcguca ccacacccgu cagcaccuac augcuaacga      720

acuccgaacu cuugucgcuc aucaacgaca ugcccauaac caacgaccaa aagaaacuaa      780

uguccaauaa cguacaaauc guacgccaac aaucuuacuc caucaugugc aucauaaaag      840

aagaaguacu agcuuacguc guccaacucc cacuguacgg agucaucgac acccccugcu      900

ggaaacucca caccucuccc cucugcacca ccaacaccaa agagggcucc aacauuugcc      960

ugacacgcac cgaccgcggc ugguacugcg acaacgcagg cuccgucucg uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaagucaau cuaugcaacg uagacaucuu caacccgaaa uaugacugca     1140

aaauuaugac aucuaaaacc gacguguccu ccucagucau cacuucccua ggagccaucg     1200

uuuccuguua cggcaagacc aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa     1260

ccuucuccaa cggaugugac uaugucucca acaagggcgu cgacaccguc agcgucggca     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu cuacgucaaa ggagagccca     1380

uaaucaacuu cuacgacccc cucgucuucc cauccgacga guucgacgcc ucaaucuccc     1440

aagucaacga gaaaaucaac caauccuuag ccuucauccg uaaguccgac gaacuccuuc     1500

acaacgucaa cgccgguaaa ucuaccacca acaucaugau aacaacaaua auuaucguca     1560

ucaucgucau ccuccuuucc cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu     1620

ccaccccagu aacccucucu aaagaccaac ucagcggaau caauaacaua gccuucagca     1680

auuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  2615
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2615
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2616
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2616
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2617
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2617
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2618
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2618
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau aaacaauauc gcauucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2619
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2619
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2620
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2620
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau uaacaauauc gcuuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2621
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2621
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac      120

uuaccgccgu aacauuuugc uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau      180

caacaugcuc agcagucucc aaaggauacc uuggagcauu aagaaccggc ugguauaccu      240

ccguaauaac aauugaacua ucuaauauaa aagaaaauaa auguaaugga acugacgcaa      300

aaguuaaacu aauaaaacaa gaacucgaca aauacaaaaa cgccgucaca gaccuacaac      360

uacuaaugca aucaaccccc gcaacaggau caggauccgc aaucugcagc ggcgucgcag      420

uuugcaaagu ccuacauuua gaaggagaag uaaacaaaau aaaaucugcu cuccucucua      480

caaacaaagc aguaguguca cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag      540

accuaaaaaa uuacauagac aaacaacuac uuccaauucu aaacaaacaa uccuguucca      600

uacccaacau agaaacagua auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua      660

caagagaauu uuccgucaau gcaggaguaa caaccccagu aucaaccuac auguuaacua      720

acucagaacu cuuaucacua auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca      780

ugucaaauaa cguacaaaua guccgacaac aaucauacuc caucaugugc auuauaaaag      840

aagaaguacu agcauacguc guccaauuac cacuauacgg cgucauagac acaccauguu      900

ggaaacucca cacaucacca cuaugcacua caaauacaaa agaaggcucc aacaucugcc      960

uaacaagaac agacagaggu ugguauugcg acaacgcagg aucaguauca uuuuuccccc     1020

aagcagaaac auguaaagua caaucaaaua gagucuucug cgacaccaug aacucauuaa     1080

cacuaccuuc agaagucaac cuaugcaacg uagacaucuu caacccuaaa uaugacugca     1140

aaaucaugac cagcaaaacc gacguuucau cuuccguaau aacaucacua ggcgcaauag     1200

ucucauguua cggcaaaaca aaauguacag caucaaauaa aaaccgugga auaauaaaaa     1260

cauuuucuaa ugguugugac uacguaagca auaaaggagu agauacagua ucagucggca     1320

acaccuuaua cuguguaaac aaacaagaag gccaaaguuu auacgucaaa ggagaaccca     1380

ucaucaacuu cuacgaccca uuaguauucc caucagacga auuugaugca agcauuucac     1440

aagucaacga aaaaaucaau caaucauuag cauucauccg aaaaucagac gaauuauuac     1500

acaacguaaa cgccggaaaa ucaaccacua auauaaugau aaccacaaua aucaucguaa     1560

uaauaguaau acuucucuca cuaaucgcag ucggacuccu ucuauacugc aaagcaagau     1620

cuacaccagu aacacuaucc aaagaucaac uaaguggcau aaacaacaua gcauuuucua     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2622
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2622
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuaaaagc caacgcgauc accacaaucc      120

ugacagccgu caccuucugc uucgccuccg gccaaaacau caccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aagggcuacc ugggcgcacu ucguacaggc ugguacaccu      240

ccguaauaac caucgaacuc uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaagcaa gaacuugaca aauacaaaaa ugcagucacc gaccuucaac      360

uccucaugca aucuaccccc gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggugaag uaaacaaaau aaaauccgcc cuccucucca      480

ccaacaaagc cgucgucucc cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg      540

accugaaaaa cuacauagac aaacagcucc uaccaauccu uaacaaacag agcugcucca      600

uuccgaauau cgaaacggua aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa      660

cgcgagaguu cuccguaaac gcuggcguca ccacacccgu cagcaccuac augcuaacga      720

acuccgaacu cuugucgcuc aucaacgaca ugcccauaac caacgaccaa aagaaacuaa      780

uguccaauaa cguacaaauc guacgccaac aaucuuacuc caucaugugc aucauaaaag      840

aagaaguacu agcuuacguc guccaacucc cacuguacgg agucaucgac acccccugcu      900

ggaaacucca caccucuccc cucugcacca ccaacaccaa agagggcucc aacauuugcc      960

ugacacgcac cgaccgcggc ugguacugcg acaacgcagg cuccgucucg uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaagucaau cuaugcaacg uagacaucuu caacccgaaa uaugacugca     1140

aaauuaugac aucuaaaacc gacguguccu ccucagucau cacuucccua ggagccaucg     1200

uuuccuguua cggcaagacc aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa     1260

ccuucuccaa cggaugugac uaugucucca acaagggcgu cgacaccguc agcgucggca     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu cuacgucaaa ggagagccca     1380

uaaucaacuu cuacgacccc cucgucuucc cauccgacga guucgacgcc ucaaucuccc     1440

aagucaacga gaaaaucaac caauccuuag ccuucauccg uaaguccgac gaacuccuuc     1500

acaacgucaa cgccgguaaa ucuaccacca acaucaugau aacaacaaua auuaucguca     1560

ucaucgucau ccuccuuucc cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu     1620

ccaccccagu aacccucucu aaagaccaac ucagcggaau caauaacaua gccuucagca     1680

auuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  2623
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2623
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2624
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2624
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2625
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2625
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2626
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2626
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2627
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2627
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2628
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2628
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2629
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2629
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gcaaacgcaa uuacaacuau acuuaccgcc      120

guaacauuuu gcuucgcauc ugggcaaaac auuaccgaag aauuuuauca aucaacaugc      180

ucagcagucu ccaaaggaua ccuuggagca uuaagaaccg gcugguauac cuccguaaua      240

acaauugaac uaucuaauau aaaagaaaau aaauguaaug gaacugacgc aaaaguuaaa      300

cuaauaaaac aagaacucga caaauacaaa aacgccguca cagaccuaca acuacuaaug      360

caaucaaccc ccgcaacagg aucaggaucc gcaaucugca gcggcgucgc aguuugcaaa      420

guccuacauu uagaaggaga aguaaacaaa auaaaaucug cucuccucuc uacaaacaaa      480

gcaguagugu cacuuucaaa cggaguauca guucuaacau ucaaaguacu agaccuaaaa      540

aauuacauag acaaacaacu acuuccaauu cuaaacaaac aauccuguuc cauacccaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagac uccuagaaau uacaagagaa      660

uuuuccguca augcaggagu aacaacccca guaucaaccu acauguuaac uaacucagaa      720

cucuuaucac uaauaaacga caugccaauc acuaaugacc aaaaaaaacu caugucaaau      780

aacguacaaa uaguccgaca acaaucauac uccaucaugu gcauuauaaa agaagaagua      840

cuagcauacg ucguccaauu accacuauac ggcgucauag acacaccaug uuggaaacuc      900

cacacaucac cacuaugcac uacaaauaca aaagaaggcu ccaacaucug ccuaacaaga      960

acagacagag guugguauug cgacaacgca ggaucaguau cauuuuuccc ccaagcagaa     1020

acauguaaag uacaaucaaa uagagucuuc ugcgacacca ugaacucauu aacacuaccu     1080

ucagaaguca accuaugcaa cguagacauc uucaacccua aauaugacug caaaaucaug     1140

accagcaaaa ccgacguuuc aucuuccgua auaacaucac uaggcgcaau agucucaugu     1200

uacggcaaaa caaaauguac agcaucaaau aaaaaccgug gaauaauaaa aacauuuucu     1260

aaugguugug acuacguaag caauaaagga guagauacag uaucagucgg caacaccuua     1320

uacuguguaa acaaacaaga aggccaaagu uuauacguca aaggagaacc caucaucaac     1380

uucuacgacc cauuaguauu cccaucagac gaauuugaug caagcauuuc acaagucaac     1440

gaaaaaauca aucaaucauu agcauucauc cgaaaaucag acgaauuauu acacaacgua     1500

aacgccggaa aaucaaccac uaauauaaug auaaccacaa uaaucaucgu aauaauagua     1560

auacuucucu cacuaaucgc agucggacuc cuucuauacu gcaaagcaag aucuacacca     1620

guaacacuau ccaaagauca acuaaguggc auaaacaaca uagcauuuuc uaacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2630
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2630
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuaaaa gccaacgcga ucaccacaau ccugacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaagggcua ccugggcgca cuucguacag gcugguacac cuccguaaua      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaagc aagaacuuga caaauacaaa aaugcaguca ccgaccuuca acuccucaug      360

caaucuaccc ccgccacagg cuccggcucc gcuaucugcu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaagguga aguaaacaaa auaaaauccg cccuccucuc caccaacaaa      480

gccgucgucu cccuaucaaa cggcgucucc gugcucaccu ucaagguucu cgaccugaaa      540

aacuacauag acaaacagcu ccuaccaauc cuuaacaaac agagcugcuc cauuccgaau      600

aucgaaacgg uaaucgaauu ucaacagaaa aacaaccgcc uccucgaaau aacgcgagag      660

uucuccguaa acgcuggcgu caccacaccc gucagcaccu acaugcuaac gaacuccgaa      720

cucuugucgc ucaucaacga caugcccaua accaacgacc aaaagaaacu aauguccaau      780

aacguacaaa ucguacgcca acaaucuuac uccaucaugu gcaucauaaa agaagaagua      840

cuagcuuacg ucguccaacu cccacuguac ggagucaucg acacccccug cuggaaacuc      900

cacaccucuc cccucugcac caccaacacc aaagagggcu ccaacauuug ccugacacgc      960

accgaccgcg gcugguacug cgacaacgca ggcuccgucu cguucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgaaguca aucuaugcaa cguagacauc uucaacccga aauaugacug caaaauuaug     1140

acaucuaaaa ccgacguguc cuccucaguc aucacuuccc uaggagccau cguuuccugu     1200

uacggcaaga ccaaaugcac cgccagcaac aaaaaccgag gcaucaucaa aaccuucucc     1260

aacggaugug acuaugucuc caacaagggc gucgacaccg ucagcgucgg caacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cucuacguca aaggagagcc cauaaucaac     1380

uucuacgacc cccucgucuu cccauccgac gaguucgacg ccucaaucuc ccaagucaac     1440

gagaaaauca accaauccuu agccuucauc cguaaguccg acgaacuccu ucacaacguc     1500

aacgccggua aaucuaccac caacaucaug auaacaacaa uaauuaucgu caucaucguc     1560

auccuccuuu cccucaucgc ggucgggcua uugcucuacu gcaaagcccg guccacccca     1620

guaacccucu cuaaagacca acucagcgga aucaauaaca uagccuucag caauuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  2631
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2631
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2632
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2632
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2633
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2633
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2634
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2634
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg auaaacaaua ucgcauucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2635
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2635
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2636
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2636
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga auuaacaaua ucgcuuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2637
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2637
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccuaaaa gcaaacgcaa uuacaacuau acuuaccgcc      120

guaacauuuu gcuucgcauc ugggcaaaac auuaccgaag aauuuuauca aucaacaugc      180

ucagcagucu ccaaaggaua ccuuggagca uuaagaaccg gcugguauac cuccguaaua      240

acaauugaac uaucuaauau aaaagaaaau aaauguaaug gaacugacgc aaaaguuaaa      300

cuaauaaaac aagaacucga caaauacaaa aacgccguca cagaccuaca acuacuaaug      360

caaucaaccc ccgcaacagg aucaggaucc gcaaucugca gcggcgucgc aguuugcaaa      420

guccuacauu uagaaggaga aguaaacaaa auaaaaucug cucuccucuc uacaaacaaa      480

gcaguagugu cacuuucaaa cggaguauca guucuaacau ucaaaguacu agaccuaaaa      540

aauuacauag acaaacaacu acuuccaauu cuaaacaaac aauccuguuc cauacccaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagac uccuagaaau uacaagagaa      660

uuuuccguca augcaggagu aacaacccca guaucaaccu acauguuaac uaacucagaa      720

cucuuaucac uaauaaacga caugccaauc acuaaugacc aaaaaaaacu caugucaaau      780

aacguacaaa uaguccgaca acaaucauac uccaucaugu gcauuauaaa agaagaagua      840

cuagcauacg ucguccaauu accacuauac ggcgucauag acacaccaug uuggaaacuc      900

cacacaucac cacuaugcac uacaaauaca aaagaaggcu ccaacaucug ccuaacaaga      960

acagacagag guugguauug cgacaacgca ggaucaguau cauuuuuccc ccaagcagaa     1020

acauguaaag uacaaucaaa uagagucuuc ugcgacacca ugaacucauu aacacuaccu     1080

ucagaaguca accuaugcaa cguagacauc uucaacccua aauaugacug caaaaucaug     1140

accagcaaaa ccgacguuuc aucuuccgua auaacaucac uaggcgcaau agucucaugu     1200

uacggcaaaa caaaauguac agcaucaaau aaaaaccgug gaauaauaaa aacauuuucu     1260

aaugguugug acuacguaag caauaaagga guagauacag uaucagucgg caacaccuua     1320

uacuguguaa acaaacaaga aggccaaagu uuauacguca aaggagaacc caucaucaac     1380

uucuacgacc cauuaguauu cccaucagac gaauuugaug caagcauuuc acaagucaac     1440

gaaaaaauca aucaaucauu agcauucauc cgaaaaucag acgaauuauu acacaacgua     1500

aacgccggaa aaucaaccac uaauauaaug auaaccacaa uaaucaucgu aauaauagua     1560

auacuucucu cacuaaucgc agucggacuc cuucuauacu gcaaagcaag aucuacacca     1620

guaacacuau ccaaagauca acuaaguggc auaaacaaca uagcauuuuc uaacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2638
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2638
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuaaaa gccaacgcga ucaccacaau ccugacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaagggcua ccugggcgca cuucguacag gcugguacac cuccguaaua      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaagc aagaacuuga caaauacaaa aaugcaguca ccgaccuuca acuccucaug      360

caaucuaccc ccgccacagg cuccggcucc gcuaucugcu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaagguga aguaaacaaa auaaaauccg cccuccucuc caccaacaaa      480

gccgucgucu cccuaucaaa cggcgucucc gugcucaccu ucaagguucu cgaccugaaa      540

aacuacauag acaaacagcu ccuaccaauc cuuaacaaac agagcugcuc cauuccgaau      600

aucgaaacgg uaaucgaauu ucaacagaaa aacaaccgcc uccucgaaau aacgcgagag      660

uucuccguaa acgcuggcgu caccacaccc gucagcaccu acaugcuaac gaacuccgaa      720

cucuugucgc ucaucaacga caugcccaua accaacgacc aaaagaaacu aauguccaau      780

aacguacaaa ucguacgcca acaaucuuac uccaucaugu gcaucauaaa agaagaagua      840

cuagcuuacg ucguccaacu cccacuguac ggagucaucg acacccccug cuggaaacuc      900

cacaccucuc cccucugcac caccaacacc aaagagggcu ccaacauuug ccugacacgc      960

accgaccgcg gcugguacug cgacaacgca ggcuccgucu cguucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgaaguca aucuaugcaa cguagacauc uucaacccga aauaugacug caaaauuaug     1140

acaucuaaaa ccgacguguc cuccucaguc aucacuuccc uaggagccau cguuuccugu     1200

uacggcaaga ccaaaugcac cgccagcaac aaaaaccgag gcaucaucaa aaccuucucc     1260

aacggaugug acuaugucuc caacaagggc gucgacaccg ucagcgucgg caacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cucuacguca aaggagagcc cauaaucaac     1380

uucuacgacc cccucgucuu cccauccgac gaguucgacg ccucaaucuc ccaagucaac     1440

gagaaaauca accaauccuu agccuucauc cguaaguccg acgaacuccu ucacaacguc     1500

aacgccggua aaucuaccac caacaucaug auaacaacaa uaauuaucgu caucaucguc     1560

auccuccuuu cccucaucgc ggucgggcua uugcucuacu gcaaagcccg guccacccca     1620

guaacccucu cuaaagacca acucagcgga aucaauaaca uagccuucag caauuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  2639
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2639
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2640
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2640
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2641
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2641
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2642
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2642
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2643
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2643
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2644
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2644
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2645
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2645
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagca      120

aacgcaauua caacuauacu uaccgccgua acauuuugcu ucgcaucugg gcaaaacauu      180

accgaagaau uuuaucaauc aacaugcuca gcagucucca aaggauaccu uggagcauua      240

agaaccggcu gguauaccuc cguaauaaca auugaacuau cuaauauaaa agaaaauaaa      300

uguaauggaa cugacgcaaa aguuaaacua auaaaacaag aacucgacaa auacaaaaac      360

gccgucacag accuacaacu acuaaugcaa ucaacccccg caacaggauc aggauccgca      420

aucugcagcg gcgucgcagu uugcaaaguc cuacauuuag aaggagaagu aaacaaaaua      480

aaaucugcuc uccucucuac aaacaaagca guagugucac uuucaaacgg aguaucaguu      540

cuaacauuca aaguacuaga ccuaaaaaau uacauagaca aacaacuacu uccaauucua      600

aacaaacaau ccuguuccau acccaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagacucc uagaaauuac aagagaauuu uccgucaaug caggaguaac aaccccagua      720

ucaaccuaca uguuaacuaa cucagaacuc uuaucacuaa uaaacgacau gccaaucacu      780

aaugaccaaa aaaaacucau gucaaauaac guacaaauag uccgacaaca aucauacucc      840

aucaugugca uuauaaaaga agaaguacua gcauacgucg uccaauuacc acuauacggc      900

gucauagaca caccauguug gaaacuccac acaucaccac uaugcacuac aaauacaaaa      960

gaaggcucca acaucugccu aacaagaaca gacagagguu gguauugcga caacgcagga     1020

ucaguaucau uuuuccccca agcagaaaca uguaaaguac aaucaaauag agucuucugc     1080

gacaccauga acucauuaac acuaccuuca gaagucaacc uaugcaacgu agacaucuuc     1140

aacccuaaau augacugcaa aaucaugacc agcaaaaccg acguuucauc uuccguaaua     1200

acaucacuag gcgcaauagu cucauguuac ggcaaaacaa aauguacagc aucaaauaaa     1260

aaccguggaa uaauaaaaac auuuucuaau gguugugacu acguaagcaa uaaaggagua     1320

gauacaguau cagucggcaa caccuuauac uguguaaaca aacaagaagg ccaaaguuua     1380

uacgucaaag gagaacccau caucaacuuc uacgacccau uaguauuccc aucagacgaa     1440

uuugaugcaa gcauuucaca agucaacgaa aaaaucaauc aaucauuagc auucauccga     1500

aaaucagacg aauuauuaca caacguaaac gccggaaaau caaccacuaa uauaaugaua     1560

accacaauaa ucaucguaau aauaguaaua cuucucucac uaaucgcagu cggacuccuu     1620

cuauacugca aagcaagauc uacaccagua acacuaucca aagaucaacu aaguggcaua     1680

aacaacauag cauuuucuaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2646
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2646
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuaaaagcc      120

aacgcgauca ccacaauccu gacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca agggcuaccu gggcgcacuu      240

cguacaggcu gguacaccuc cguaauaacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaagcaag aacuugacaa auacaaaaau      360

gcagucaccg accuucaacu ccucaugcaa ucuacccccg ccacaggcuc cggcuccgcu      420

aucugcuccg gcgucgccgu cugcaaaguc cuccaccucg aaggugaagu aaacaaaaua      480

aaauccgccc uccucuccac caacaaagcc gucgucuccc uaucaaacgg cgucuccgug      540

cucaccuuca agguucucga ccugaaaaac uacauagaca aacagcuccu accaauccuu      600

aacaaacaga gcugcuccau uccgaauauc gaaacgguaa ucgaauuuca acagaaaaac      660

aaccgccucc ucgaaauaac gcgagaguuc uccguaaacg cuggcgucac cacacccguc      720

agcaccuaca ugcuaacgaa cuccgaacuc uugucgcuca ucaacgacau gcccauaacc      780

aacgaccaaa agaaacuaau guccaauaac guacaaaucg uacgccaaca aucuuacucc      840

aucaugugca ucauaaaaga agaaguacua gcuuacgucg uccaacuccc acuguacgga      900

gucaucgaca cccccugcug gaaacuccac accucucccc ucugcaccac caacaccaaa      960

gagggcucca acauuugccu gacacgcacc gaccgcggcu gguacugcga caacgcaggc     1020

uccgucucgu ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaagucaauc uaugcaacgu agacaucuuc     1140

aacccgaaau augacugcaa aauuaugaca ucuaaaaccg acguguccuc cucagucauc     1200

acuucccuag gagccaucgu uuccuguuac ggcaagacca aaugcaccgc cagcaacaaa     1260

aaccgaggca ucaucaaaac cuucuccaac ggaugugacu augucuccaa caagggcguc     1320

gacaccguca gcgucggcaa cacccucuac ugcgucaaca aacaagaagg ccaaucccuc     1380

uacgucaaag gagagcccau aaucaacuuc uacgaccccc ucgucuuccc auccgacgag     1440

uucgacgccu caaucuccca agucaacgag aaaaucaacc aauccuuagc cuucauccgu     1500

aaguccgacg aacuccuuca caacgucaac gccgguaaau cuaccaccaa caucaugaua     1560

acaacaauaa uuaucgucau caucgucauc cuccuuuccc ucaucgcggu cgggcuauug     1620

cucuacugca aagcccgguc caccccagua acccucucua aagaccaacu cagcggaauc     1680

aauaacauag ccuucagcaa uuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  2647
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2647
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2648
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2648
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2649
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2649
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2650
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2650
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggaua     1680

aacaauaucg cauucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2651
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2651
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2652
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2652
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauu     1680

aacaauaucg cuuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2653
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2653
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccuaaaagca      120

aacgcaauua caacuauacu uaccgccgua acauuuugcu ucgcaucugg gcaaaacauu      180

accgaagaau uuuaucaauc aacaugcuca gcagucucca aaggauaccu uggagcauua      240

agaaccggcu gguauaccuc cguaauaaca auugaacuau cuaauauaaa agaaaauaaa      300

uguaauggaa cugacgcaaa aguuaaacua auaaaacaag aacucgacaa auacaaaaac      360

gccgucacag accuacaacu acuaaugcaa ucaacccccg caacaggauc aggauccgca      420

aucugcagcg gcgucgcagu uugcaaaguc cuacauuuag aaggagaagu aaacaaaaua      480

aaaucugcuc uccucucuac aaacaaagca guagugucac uuucaaacgg aguaucaguu      540

cuaacauuca aaguacuaga ccuaaaaaau uacauagaca aacaacuacu uccaauucua      600

aacaaacaau ccuguuccau acccaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagacucc uagaaauuac aagagaauuu uccgucaaug caggaguaac aaccccagua      720

ucaaccuaca uguuaacuaa cucagaacuc uuaucacuaa uaaacgacau gccaaucacu      780

aaugaccaaa aaaaacucau gucaaauaac guacaaauag uccgacaaca aucauacucc      840

aucaugugca uuauaaaaga agaaguacua gcauacgucg uccaauuacc acuauacggc      900

gucauagaca caccauguug gaaacuccac acaucaccac uaugcacuac aaauacaaaa      960

gaaggcucca acaucugccu aacaagaaca gacagagguu gguauugcga caacgcagga     1020

ucaguaucau uuuuccccca agcagaaaca uguaaaguac aaucaaauag agucuucugc     1080

gacaccauga acucauuaac acuaccuuca gaagucaacc uaugcaacgu agacaucuuc     1140

aacccuaaau augacugcaa aaucaugacc agcaaaaccg acguuucauc uuccguaaua     1200

acaucacuag gcgcaauagu cucauguuac ggcaaaacaa aauguacagc aucaaauaaa     1260

aaccguggaa uaauaaaaac auuuucuaau gguugugacu acguaagcaa uaaaggagua     1320

gauacaguau cagucggcaa caccuuauac uguguaaaca aacaagaagg ccaaaguuua     1380

uacgucaaag gagaacccau caucaacuuc uacgacccau uaguauuccc aucagacgaa     1440

uuugaugcaa gcauuucaca agucaacgaa aaaaucaauc aaucauuagc auucauccga     1500

aaaucagacg aauuauuaca caacguaaac gccggaaaau caaccacuaa uauaaugaua     1560

accacaauaa ucaucguaau aauaguaaua cuucucucac uaaucgcagu cggacuccuu     1620

cuauacugca aagcaagauc uacaccagua acacuaucca aagaucaacu aaguggcaua     1680

aacaacauag cauuuucuaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2654
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2654
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuaaaagcc      120

aacgcgauca ccacaauccu gacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca agggcuaccu gggcgcacuu      240

cguacaggcu gguacaccuc cguaauaacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaagcaag aacuugacaa auacaaaaau      360

gcagucaccg accuucaacu ccucaugcaa ucuacccccg ccacaggcuc cggcuccgcu      420

aucugcuccg gcgucgccgu cugcaaaguc cuccaccucg aaggugaagu aaacaaaaua      480

aaauccgccc uccucuccac caacaaagcc gucgucuccc uaucaaacgg cgucuccgug      540

cucaccuuca agguucucga ccugaaaaac uacauagaca aacagcuccu accaauccuu      600

aacaaacaga gcugcuccau uccgaauauc gaaacgguaa ucgaauuuca acagaaaaac      660

aaccgccucc ucgaaauaac gcgagaguuc uccguaaacg cuggcgucac cacacccguc      720

agcaccuaca ugcuaacgaa cuccgaacuc uugucgcuca ucaacgacau gcccauaacc      780

aacgaccaaa agaaacuaau guccaauaac guacaaaucg uacgccaaca aucuuacucc      840

aucaugugca ucauaaaaga agaaguacua gcuuacgucg uccaacuccc acuguacgga      900

gucaucgaca cccccugcug gaaacuccac accucucccc ucugcaccac caacaccaaa      960

gagggcucca acauuugccu gacacgcacc gaccgcggcu gguacugcga caacgcaggc     1020

uccgucucgu ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaagucaauc uaugcaacgu agacaucuuc     1140

aacccgaaau augacugcaa aauuaugaca ucuaaaaccg acguguccuc cucagucauc     1200

acuucccuag gagccaucgu uuccuguuac ggcaagacca aaugcaccgc cagcaacaaa     1260

aaccgaggca ucaucaaaac cuucuccaac ggaugugacu augucuccaa caagggcguc     1320

gacaccguca gcgucggcaa cacccucuac ugcgucaaca aacaagaagg ccaaucccuc     1380

uacgucaaag gagagcccau aaucaacuuc uacgaccccc ucgucuuccc auccgacgag     1440

uucgacgccu caaucuccca agucaacgag aaaaucaacc aauccuuagc cuucauccgu     1500

aaguccgacg aacuccuuca caacgucaac gccgguaaau cuaccaccaa caucaugaua     1560

acaacaauaa uuaucgucau caucgucauc cuccuuuccc ucaucgcggu cgggcuauug     1620

cucuacugca aagcccgguc caccccagua acccucucua aagaccaacu cagcggaauc     1680

aauaacauag ccuucagcaa uuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  2655
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2655
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2656
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2656
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2657
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2657
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2658
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2658
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2659
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2659
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2660
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2660
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2661
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2661
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu aaaagcaaac gcaauuacaa cuauacuuac cgccguaaca      180

uuuugcuucg caucugggca aaacauuacc gaagaauuuu aucaaucaac augcucagca      240

gucuccaaag gauaccuugg agcauuaaga accggcuggu auaccuccgu aauaacaauu      300

gaacuaucua auauaaaaga aaauaaaugu aauggaacug acgcaaaagu uaaacuaaua      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagacc uacaacuacu aaugcaauca      420

acccccgcaa caggaucagg auccgcaauc ugcagcggcg ucgcaguuug caaaguccua      480

cauuuagaag gagaaguaaa caaaauaaaa ucugcucucc ucucuacaaa caaagcagua      540

gugucacuuu caaacggagu aucaguucua acauucaaag uacuagaccu aaaaaauuac      600

auagacaaac aacuacuucc aauucuaaac aaacaauccu guuccauacc caacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agacuccuag aaauuacaag agaauuuucc      720

gucaaugcag gaguaacaac cccaguauca accuacaugu uaacuaacuc agaacucuua      780

ucacuaauaa acgacaugcc aaucacuaau gaccaaaaaa aacucauguc aaauaacgua      840

caaauagucc gacaacaauc auacuccauc augugcauua uaaaagaaga aguacuagca      900

uacgucgucc aauuaccacu auacggcguc auagacacac cauguuggaa acuccacaca      960

ucaccacuau gcacuacaaa uacaaaagaa ggcuccaaca ucugccuaac aagaacagac     1020

agagguuggu auugcgacaa cgcaggauca guaucauuuu ucccccaagc agaaacaugu     1080

aaaguacaau caaauagagu cuucugcgac accaugaacu cauuaacacu accuucagaa     1140

gucaaccuau gcaacguaga caucuucaac ccuaaauaug acugcaaaau caugaccagc     1200

aaaaccgacg uuucaucuuc cguaauaaca ucacuaggcg caauagucuc auguuacggc     1260

aaaacaaaau guacagcauc aaauaaaaac cguggaauaa uaaaaacauu uucuaauggu     1320

ugugacuacg uaagcaauaa aggaguagau acaguaucag ucggcaacac cuuauacugu     1380

guaaacaaac aagaaggcca aaguuuauac gucaaaggag aacccaucau caacuucuac     1440

gacccauuag uauucccauc agacgaauuu gaugcaagca uuucacaagu caacgaaaaa     1500

aucaaucaau cauuagcauu cauccgaaaa ucagacgaau uauuacacaa cguaaacgcc     1560

ggaaaaucaa ccacuaauau aaugauaacc acaauaauca ucguaauaau aguaauacuu     1620

cucucacuaa ucgcagucgg acuccuucua uacugcaaag caagaucuac accaguaaca     1680

cuauccaaag aucaacuaag uggcauaaac aacauagcau uuucuaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2662
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2662
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu aaaagccaac gcgaucacca caauccugac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaagaguucu accaauccac augcuccgcc      240

gucuccaagg gcuaccuggg cgcacuucgu acaggcuggu acaccuccgu aauaaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aagcaagaac uugacaaaua caaaaaugca gucaccgacc uucaacuccu caugcaaucu      420

acccccgcca caggcuccgg cuccgcuauc ugcuccggcg ucgccgucug caaaguccuc      480

caccucgaag gugaaguaaa caaaauaaaa uccgcccucc ucuccaccaa caaagccguc      540

gucucccuau caaacggcgu cuccgugcuc accuucaagg uucucgaccu gaaaaacuac      600

auagacaaac agcuccuacc aauccuuaac aaacagagcu gcuccauucc gaauaucgaa      660

acgguaaucg aauuucaaca gaaaaacaac cgccuccucg aaauaacgcg agaguucucc      720

guaaacgcug gcgucaccac acccgucagc accuacaugc uaacgaacuc cgaacucuug      780

ucgcucauca acgacaugcc cauaaccaac gaccaaaaga aacuaauguc caauaacgua      840

caaaucguac gccaacaauc uuacuccauc augugcauca uaaaagaaga aguacuagcu      900

uacgucgucc aacucccacu guacggaguc aucgacaccc ccugcuggaa acuccacacc      960

ucuccccucu gcaccaccaa caccaaagag ggcuccaaca uuugccugac acgcaccgac     1020

cgcggcuggu acugcgacaa cgcaggcucc gucucguucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgaa     1140

gucaaucuau gcaacguaga caucuucaac ccgaaauaug acugcaaaau uaugacaucu     1200

aaaaccgacg uguccuccuc agucaucacu ucccuaggag ccaucguuuc cuguuacggc     1260

aagaccaaau gcaccgccag caacaaaaac cgaggcauca ucaaaaccuu cuccaacgga     1320

ugugacuaug ucuccaacaa gggcgucgac accgucagcg ucggcaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccucuac gucaaaggag agcccauaau caacuucuac     1440

gacccccucg ucuucccauc cgacgaguuc gacgccucaa ucucccaagu caacgagaaa     1500

aucaaccaau ccuuagccuu cauccguaag uccgacgaac uccuucacaa cgucaacgcc     1560

gguaaaucua ccaccaacau caugauaaca acaauaauua ucgucaucau cgucauccuc     1620

cuuucccuca ucgcggucgg gcuauugcuc uacugcaaag cccgguccac cccaguaacc     1680

cucucuaaag accaacucag cggaaucaau aacauagccu ucagcaauua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2663
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2663
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2664
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2664
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2665
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2665
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2666
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2666
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2667
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2667
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2668
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2668
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2669
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2669
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gcaaacgcaa uuacaacuau acuuaccgcc guaacauuuu gcuucgcauc ugggcaaaac      180

auuaccgaag aauuuuauca aucaacaugc ucagcagucu ccaaaggaua ccuuggagca      240

uuaagaaccg gcugguauac cuccguaaua acaauugaac uaucuaauau aaaagaaaau      300

aaauguaaug gaacugacgc aaaaguuaaa cuaauaaaac aagaacucga caaauacaaa      360

aacgccguca cagaccuaca acuacuaaug caaucaaccc ccgcaacagg aucaggaucc      420

gcaaucugca gcggcgucgc aguuugcaaa guccuacauu uagaaggaga aguaaacaaa      480

auaaaaucug cucuccucuc uacaaacaaa gcaguagugu cacuuucaaa cggaguauca      540

guucuaacau ucaaaguacu agaccuaaaa aauuacauag acaaacaacu acuuccaauu      600

cuaaacaaac aauccuguuc cauacccaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagac uccuagaaau uacaagagaa uuuuccguca augcaggagu aacaacccca      720

guaucaaccu acauguuaac uaacucagaa cucuuaucac uaauaaacga caugccaauc      780

acuaaugacc aaaaaaaacu caugucaaau aacguacaaa uaguccgaca acaaucauac      840

uccaucaugu gcauuauaaa agaagaagua cuagcauacg ucguccaauu accacuauac      900

ggcgucauag acacaccaug uuggaaacuc cacacaucac cacuaugcac uacaaauaca      960

aaagaaggcu ccaacaucug ccuaacaaga acagacagag guugguauug cgacaacgca     1020

ggaucaguau cauuuuuccc ccaagcagaa acauguaaag uacaaucaaa uagagucuuc     1080

ugcgacacca ugaacucauu aacacuaccu ucagaaguca accuaugcaa cguagacauc     1140

uucaacccua aauaugacug caaaaucaug accagcaaaa ccgacguuuc aucuuccgua     1200

auaacaucac uaggcgcaau agucucaugu uacggcaaaa caaaauguac agcaucaaau     1260

aaaaaccgug gaauaauaaa aacauuuucu aaugguugug acuacguaag caauaaagga     1320

guagauacag uaucagucgg caacaccuua uacuguguaa acaaacaaga aggccaaagu     1380

uuauacguca aaggagaacc caucaucaac uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug caagcauuuc acaagucaac gaaaaaauca aucaaucauu agcauucauc     1500

cgaaaaucag acgaauuauu acacaacgua aacgccggaa aaucaaccac uaauauaaug     1560

auaaccacaa uaaucaucgu aauaauagua auacuucucu cacuaaucgc agucggacuc     1620

cuucuauacu gcaaagcaag aucuacacca guaacacuau ccaaagauca acuaaguggc     1680

auaaacaaca uagcauuuuc uaacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2670
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2670
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuaaaa      120

gccaacgcga ucaccacaau ccugacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgaag aguucuacca auccacaugc uccgccgucu ccaagggcua ccugggcgca      240

cuucguacag gcugguacac cuccguaaua accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaagc aagaacuuga caaauacaaa      360

aaugcaguca ccgaccuuca acuccucaug caaucuaccc ccgccacagg cuccggcucc      420

gcuaucugcu ccggcgucgc cgucugcaaa guccuccacc ucgaagguga aguaaacaaa      480

auaaaauccg cccuccucuc caccaacaaa gccgucgucu cccuaucaaa cggcgucucc      540

gugcucaccu ucaagguucu cgaccugaaa aacuacauag acaaacagcu ccuaccaauc      600

cuuaacaaac agagcugcuc cauuccgaau aucgaaacgg uaaucgaauu ucaacagaaa      660

aacaaccgcc uccucgaaau aacgcgagag uucuccguaa acgcuggcgu caccacaccc      720

gucagcaccu acaugcuaac gaacuccgaa cucuugucgc ucaucaacga caugcccaua      780

accaacgacc aaaagaaacu aauguccaau aacguacaaa ucguacgcca acaaucuuac      840

uccaucaugu gcaucauaaa agaagaagua cuagcuuacg ucguccaacu cccacuguac      900

ggagucaucg acacccccug cuggaaacuc cacaccucuc cccucugcac caccaacacc      960

aaagagggcu ccaacauuug ccugacacgc accgaccgcg gcugguacug cgacaacgca     1020

ggcuccgucu cguucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgaaguca aucuaugcaa cguagacauc     1140

uucaacccga aauaugacug caaaauuaug acaucuaaaa ccgacguguc cuccucaguc     1200

aucacuuccc uaggagccau cguuuccugu uacggcaaga ccaaaugcac cgccagcaac     1260

aaaaaccgag gcaucaucaa aaccuucucc aacggaugug acuaugucuc caacaagggc     1320

gucgacaccg ucagcgucgg caacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cucuacguca aaggagagcc cauaaucaac uucuacgacc cccucgucuu cccauccgac     1440

gaguucgacg ccucaaucuc ccaagucaac gagaaaauca accaauccuu agccuucauc     1500

cguaaguccg acgaacuccu ucacaacguc aacgccggua aaucuaccac caacaucaug     1560

auaacaacaa uaauuaucgu caucaucguc auccuccuuu cccucaucgc ggucgggcua     1620

uugcucuacu gcaaagcccg guccacccca guaacccucu cuaaagacca acucagcgga     1680

aucaauaaca uagccuucag caauuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  2671
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2671
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2672
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2672
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2673
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2673
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2674
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2674
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2675
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2675
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2676
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2676
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2677
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2677
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gcaaacgcaa uuacaacuau acuuaccgcc guaacauuuu gcuucgcauc ugggcaaaac      180

auuaccgaag aauuuuauca aucaacaugc ucagcagucu ccaaaggaua ccuuggagca      240

uuaagaaccg gcugguauac cuccguaaua acaauugaac uaucuaauau aaaagaaaau      300

aaauguaaug gaacugacgc aaaaguuaaa cuaauaaaac aagaacucga caaauacaaa      360

aacgccguca cagaccuaca acuacuaaug caaucaaccc ccgcaacagg aucaggaucc      420

gcaaucugca gcggcgucgc aguuugcaaa guccuacauu uagaaggaga aguaaacaaa      480

auaaaaucug cucuccucuc uacaaacaaa gcaguagugu cacuuucaaa cggaguauca      540

guucuaacau ucaaaguacu agaccuaaaa aauuacauag acaaacaacu acuuccaauu      600

cuaaacaaac aauccuguuc cauacccaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagac uccuagaaau uacaagagaa uuuuccguca augcaggagu aacaacccca      720

guaucaaccu acauguuaac uaacucagaa cucuuaucac uaauaaacga caugccaauc      780

acuaaugacc aaaaaaaacu caugucaaau aacguacaaa uaguccgaca acaaucauac      840

uccaucaugu gcauuauaaa agaagaagua cuagcauacg ucguccaauu accacuauac      900

ggcgucauag acacaccaug uuggaaacuc cacacaucac cacuaugcac uacaaauaca      960

aaagaaggcu ccaacaucug ccuaacaaga acagacagag guugguauug cgacaacgca     1020

ggaucaguau cauuuuuccc ccaagcagaa acauguaaag uacaaucaaa uagagucuuc     1080

ugcgacacca ugaacucauu aacacuaccu ucagaaguca accuaugcaa cguagacauc     1140

uucaacccua aauaugacug caaaaucaug accagcaaaa ccgacguuuc aucuuccgua     1200

auaacaucac uaggcgcaau agucucaugu uacggcaaaa caaaauguac agcaucaaau     1260

aaaaaccgug gaauaauaaa aacauuuucu aaugguugug acuacguaag caauaaagga     1320

guagauacag uaucagucgg caacaccuua uacuguguaa acaaacaaga aggccaaagu     1380

uuauacguca aaggagaacc caucaucaac uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug caagcauuuc acaagucaac gaaaaaauca aucaaucauu agcauucauc     1500

cgaaaaucag acgaauuauu acacaacgua aacgccggaa aaucaaccac uaauauaaug     1560

auaaccacaa uaaucaucgu aauaauagua auacuucucu cacuaaucgc agucggacuc     1620

cuucuauacu gcaaagcaag aucuacacca guaacacuau ccaaagauca acuaaguggc     1680

auaaacaaca uagcauuuuc uaacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2678
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2678
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuaaaa      120

gccaacgcga ucaccacaau ccugacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgaag aguucuacca auccacaugc uccgccgucu ccaagggcua ccugggcgca      240

cuucguacag gcugguacac cuccguaaua accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaagc aagaacuuga caaauacaaa      360

aaugcaguca ccgaccuuca acuccucaug caaucuaccc ccgccacagg cuccggcucc      420

gcuaucugcu ccggcgucgc cgucugcaaa guccuccacc ucgaagguga aguaaacaaa      480

auaaaauccg cccuccucuc caccaacaaa gccgucgucu cccuaucaaa cggcgucucc      540

gugcucaccu ucaagguucu cgaccugaaa aacuacauag acaaacagcu ccuaccaauc      600

cuuaacaaac agagcugcuc cauuccgaau aucgaaacgg uaaucgaauu ucaacagaaa      660

aacaaccgcc uccucgaaau aacgcgagag uucuccguaa acgcuggcgu caccacaccc      720

gucagcaccu acaugcuaac gaacuccgaa cucuugucgc ucaucaacga caugcccaua      780

accaacgacc aaaagaaacu aauguccaau aacguacaaa ucguacgcca acaaucuuac      840

uccaucaugu gcaucauaaa agaagaagua cuagcuuacg ucguccaacu cccacuguac      900

ggagucaucg acacccccug cuggaaacuc cacaccucuc cccucugcac caccaacacc      960

aaagagggcu ccaacauuug ccugacacgc accgaccgcg gcugguacug cgacaacgca     1020

ggcuccgucu cguucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgaaguca aucuaugcaa cguagacauc     1140

uucaacccga aauaugacug caaaauuaug acaucuaaaa ccgacguguc cuccucaguc     1200

aucacuuccc uaggagccau cguuuccugu uacggcaaga ccaaaugcac cgccagcaac     1260

aaaaaccgag gcaucaucaa aaccuucucc aacggaugug acuaugucuc caacaagggc     1320

gucgacaccg ucagcgucgg caacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cucuacguca aaggagagcc cauaaucaac uucuacgacc cccucgucuu cccauccgac     1440

gaguucgacg ccucaaucuc ccaagucaac gagaaaauca accaauccuu agccuucauc     1500

cguaaguccg acgaacuccu ucacaacguc aacgccggua aaucuaccac caacaucaug     1560

auaacaacaa uaauuaucgu caucaucguc auccuccuuu cccucaucgc ggucgggcua     1620

uugcucuacu gcaaagcccg guccacccca guaacccucu cuaaagacca acucagcgga     1680

aucaauaaca uagccuucag caauuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  2679
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2679
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2680
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2680
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2681
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2681
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2682
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2682
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2683
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2683
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2684
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2684
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2685
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2685
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gcaaacgcaa uuacaacuau acuuaccgcc guaacauuuu gcuucgcauc ugggcaaaac      180

auuaccgaag aauuuuauca aucaacaugc ucagcagucu ccaaaggaua ccuuggagca      240

uuaagaaccg gcugguauac cuccguaaua acaauugaac uaucuaauau aaaagaaaau      300

aaauguaaug gaacugacgc aaaaguuaaa cuaauaaaac aagaacucga caaauacaaa      360

aacgccguca cagaccuaca acuacuaaug caaucaaccc ccgcaacagg aucaggaucc      420

gcaaucugca gcggcgucgc aguuugcaaa guccuacauu uagaaggaga aguaaacaaa      480

auaaaaucug cucuccucuc uacaaacaaa gcaguagugu cacuuucaaa cggaguauca      540

guucuaacau ucaaaguacu agaccuaaaa aauuacauag acaaacaacu acuuccaauu      600

cuaaacaaac aauccuguuc cauacccaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagac uccuagaaau uacaagagaa uuuuccguca augcaggagu aacaacccca      720

guaucaaccu acauguuaac uaacucagaa cucuuaucac uaauaaacga caugccaauc      780

acuaaugacc aaaaaaaacu caugucaaau aacguacaaa uaguccgaca acaaucauac      840

uccaucaugu gcauuauaaa agaagaagua cuagcauacg ucguccaauu accacuauac      900

ggcgucauag acacaccaug uuggaaacuc cacacaucac cacuaugcac uacaaauaca      960

aaagaaggcu ccaacaucug ccuaacaaga acagacagag guugguauug cgacaacgca     1020

ggaucaguau cauuuuuccc ccaagcagaa acauguaaag uacaaucaaa uagagucuuc     1080

ugcgacacca ugaacucauu aacacuaccu ucagaaguca accuaugcaa cguagacauc     1140

uucaacccua aauaugacug caaaaucaug accagcaaaa ccgacguuuc aucuuccgua     1200

auaacaucac uaggcgcaau agucucaugu uacggcaaaa caaaauguac agcaucaaau     1260

aaaaaccgug gaauaauaaa aacauuuucu aaugguugug acuacguaag caauaaagga     1320

guagauacag uaucagucgg caacaccuua uacuguguaa acaaacaaga aggccaaagu     1380

uuauacguca aaggagaacc caucaucaac uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug caagcauuuc acaagucaac gaaaaaauca aucaaucauu agcauucauc     1500

cgaaaaucag acgaauuauu acacaacgua aacgccggaa aaucaaccac uaauauaaug     1560

auaaccacaa uaaucaucgu aauaauagua auacuucucu cacuaaucgc agucggacuc     1620

cuucuauacu gcaaagcaag aucuacacca guaacacuau ccaaagauca acuaaguggc     1680

auaaacaaca uagcauuuuc uaacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2686
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2686
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuaaaa      120

gccaacgcga ucaccacaau ccugacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgaag aguucuacca auccacaugc uccgccgucu ccaagggcua ccugggcgca      240

cuucguacag gcugguacac cuccguaaua accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaagc aagaacuuga caaauacaaa      360

aaugcaguca ccgaccuuca acuccucaug caaucuaccc ccgccacagg cuccggcucc      420

gcuaucugcu ccggcgucgc cgucugcaaa guccuccacc ucgaagguga aguaaacaaa      480

auaaaauccg cccuccucuc caccaacaaa gccgucgucu cccuaucaaa cggcgucucc      540

gugcucaccu ucaagguucu cgaccugaaa aacuacauag acaaacagcu ccuaccaauc      600

cuuaacaaac agagcugcuc cauuccgaau aucgaaacgg uaaucgaauu ucaacagaaa      660

aacaaccgcc uccucgaaau aacgcgagag uucuccguaa acgcuggcgu caccacaccc      720

gucagcaccu acaugcuaac gaacuccgaa cucuugucgc ucaucaacga caugcccaua      780

accaacgacc aaaagaaacu aauguccaau aacguacaaa ucguacgcca acaaucuuac      840

uccaucaugu gcaucauaaa agaagaagua cuagcuuacg ucguccaacu cccacuguac      900

ggagucaucg acacccccug cuggaaacuc cacaccucuc cccucugcac caccaacacc      960

aaagagggcu ccaacauuug ccugacacgc accgaccgcg gcugguacug cgacaacgca     1020

ggcuccgucu cguucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgaaguca aucuaugcaa cguagacauc     1140

uucaacccga aauaugacug caaaauuaug acaucuaaaa ccgacguguc cuccucaguc     1200

aucacuuccc uaggagccau cguuuccugu uacggcaaga ccaaaugcac cgccagcaac     1260

aaaaaccgag gcaucaucaa aaccuucucc aacggaugug acuaugucuc caacaagggc     1320

gucgacaccg ucagcgucgg caacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cucuacguca aaggagagcc cauaaucaac uucuacgacc cccucgucuu cccauccgac     1440

gaguucgacg ccucaaucuc ccaagucaac gagaaaauca accaauccuu agccuucauc     1500

cguaaguccg acgaacuccu ucacaacguc aacgccggua aaucuaccac caacaucaug     1560

auaacaacaa uaauuaucgu caucaucguc auccuccuuu cccucaucgc ggucgggcua     1620

uugcucuacu gcaaagcccg guccacccca guaacccucu cuaaagacca acucagcgga     1680

aucaauaaca uagccuucag caauuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  2687
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2687
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2688
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2688
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2689
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2689
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2690
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2690
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

auaaacaaua ucgcauucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2691
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2691
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2692
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2692
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

auuaacaaua ucgcuuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2693
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2693
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccuaaaa      120

gcaaacgcaa uuacaacuau acuuaccgcc guaacauuuu gcuucgcauc ugggcaaaac      180

auuaccgaag aauuuuauca aucaacaugc ucagcagucu ccaaaggaua ccuuggagca      240

uuaagaaccg gcugguauac cuccguaaua acaauugaac uaucuaauau aaaagaaaau      300

aaauguaaug gaacugacgc aaaaguuaaa cuaauaaaac aagaacucga caaauacaaa      360

aacgccguca cagaccuaca acuacuaaug caaucaaccc ccgcaacagg aucaggaucc      420

gcaaucugca gcggcgucgc aguuugcaaa guccuacauu uagaaggaga aguaaacaaa      480

auaaaaucug cucuccucuc uacaaacaaa gcaguagugu cacuuucaaa cggaguauca      540

guucuaacau ucaaaguacu agaccuaaaa aauuacauag acaaacaacu acuuccaauu      600

cuaaacaaac aauccuguuc cauacccaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagac uccuagaaau uacaagagaa uuuuccguca augcaggagu aacaacccca      720

guaucaaccu acauguuaac uaacucagaa cucuuaucac uaauaaacga caugccaauc      780

acuaaugacc aaaaaaaacu caugucaaau aacguacaaa uaguccgaca acaaucauac      840

uccaucaugu gcauuauaaa agaagaagua cuagcauacg ucguccaauu accacuauac      900

ggcgucauag acacaccaug uuggaaacuc cacacaucac cacuaugcac uacaaauaca      960

aaagaaggcu ccaacaucug ccuaacaaga acagacagag guugguauug cgacaacgca     1020

ggaucaguau cauuuuuccc ccaagcagaa acauguaaag uacaaucaaa uagagucuuc     1080

ugcgacacca ugaacucauu aacacuaccu ucagaaguca accuaugcaa cguagacauc     1140

uucaacccua aauaugacug caaaaucaug accagcaaaa ccgacguuuc aucuuccgua     1200

auaacaucac uaggcgcaau agucucaugu uacggcaaaa caaaauguac agcaucaaau     1260

aaaaaccgug gaauaauaaa aacauuuucu aaugguugug acuacguaag caauaaagga     1320

guagauacag uaucagucgg caacaccuua uacuguguaa acaaacaaga aggccaaagu     1380

uuauacguca aaggagaacc caucaucaac uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug caagcauuuc acaagucaac gaaaaaauca aucaaucauu agcauucauc     1500

cgaaaaucag acgaauuauu acacaacgua aacgccggaa aaucaaccac uaauauaaug     1560

auaaccacaa uaaucaucgu aauaauagua auacuucucu cacuaaucgc agucggacuc     1620

cuucuauacu gcaaagcaag aucuacacca guaacacuau ccaaagauca acuaaguggc     1680

auaaacaaca uagcauuuuc uaacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2694
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2694
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuaaaa      120

gccaacgcga ucaccacaau ccugacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgaag aguucuacca auccacaugc uccgccgucu ccaagggcua ccugggcgca      240

cuucguacag gcugguacac cuccguaaua accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaagc aagaacuuga caaauacaaa      360

aaugcaguca ccgaccuuca acuccucaug caaucuaccc ccgccacagg cuccggcucc      420

gcuaucugcu ccggcgucgc cgucugcaaa guccuccacc ucgaagguga aguaaacaaa      480

auaaaauccg cccuccucuc caccaacaaa gccgucgucu cccuaucaaa cggcgucucc      540

gugcucaccu ucaagguucu cgaccugaaa aacuacauag acaaacagcu ccuaccaauc      600

cuuaacaaac agagcugcuc cauuccgaau aucgaaacgg uaaucgaauu ucaacagaaa      660

aacaaccgcc uccucgaaau aacgcgagag uucuccguaa acgcuggcgu caccacaccc      720

gucagcaccu acaugcuaac gaacuccgaa cucuugucgc ucaucaacga caugcccaua      780

accaacgacc aaaagaaacu aauguccaau aacguacaaa ucguacgcca acaaucuuac      840

uccaucaugu gcaucauaaa agaagaagua cuagcuuacg ucguccaacu cccacuguac      900

ggagucaucg acacccccug cuggaaacuc cacaccucuc cccucugcac caccaacacc      960

aaagagggcu ccaacauuug ccugacacgc accgaccgcg gcugguacug cgacaacgca     1020

ggcuccgucu cguucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgaaguca aucuaugcaa cguagacauc     1140

uucaacccga aauaugacug caaaauuaug acaucuaaaa ccgacguguc cuccucaguc     1200

aucacuuccc uaggagccau cguuuccugu uacggcaaga ccaaaugcac cgccagcaac     1260

aaaaaccgag gcaucaucaa aaccuucucc aacggaugug acuaugucuc caacaagggc     1320

gucgacaccg ucagcgucgg caacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cucuacguca aaggagagcc cauaaucaac uucuacgacc cccucgucuu cccauccgac     1440

gaguucgacg ccucaaucuc ccaagucaac gagaaaauca accaauccuu agccuucauc     1500

cguaaguccg acgaacuccu ucacaacguc aacgccggua aaucuaccac caacaucaug     1560

auaacaacaa uaauuaucgu caucaucguc auccuccuuu cccucaucgc ggucgggcua     1620

uugcucuacu gcaaagcccg guccacccca guaacccucu cuaaagacca acucagcgga     1680

aucaauaaca uagccuucag caauuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  2695
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2695
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2696
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2696
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2697
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2697
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2698
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2698
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2699
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2699
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2700
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2700
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2701
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2701
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagcaaa cgcaauuaca acuauacuua ccgccguaac auuuugcuuc      240

gcaucugggc aaaacauuac cgaagaauuu uaucaaucaa caugcucagc agucuccaaa      300

ggauaccuug gagcauuaag aaccggcugg uauaccuccg uaauaacaau ugaacuaucu      360

aauauaaaag aaaauaaaug uaauggaacu gacgcaaaag uuaaacuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cgucacagac cuacaacuac uaaugcaauc aacccccgca      480

acaggaucag gauccgcaau cugcagcggc gucgcaguuu gcaaaguccu acauuuagaa      540

ggagaaguaa acaaaauaaa aucugcucuc cucucuacaa acaaagcagu agugucacuu      600

ucaaacggag uaucaguucu aacauucaaa guacuagacc uaaaaaauua cauagacaaa      660

caacuacuuc caauucuaaa caaacaaucc uguuccauac ccaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagacuccua gaaauuacaa gagaauuuuc cgucaaugca      780

ggaguaacaa ccccaguauc aaccuacaug uuaacuaacu cagaacucuu aucacuaaua      840

aacgacaugc caaucacuaa ugaccaaaaa aaacucaugu caaauaacgu acaaauaguc      900

cgacaacaau cauacuccau caugugcauu auaaaagaag aaguacuagc auacgucguc      960

caauuaccac uauacggcgu cauagacaca ccauguugga aacuccacac aucaccacua     1020

ugcacuacaa auacaaaaga aggcuccaac aucugccuaa caagaacaga cagagguugg     1080

uauugcgaca acgcaggauc aguaucauuu uucccccaag cagaaacaug uaaaguacaa     1140

ucaaauagag ucuucugcga caccaugaac ucauuaacac uaccuucaga agucaaccua     1200

ugcaacguag acaucuucaa cccuaaauau gacugcaaaa ucaugaccag caaaaccgac     1260

guuucaucuu ccguaauaac aucacuaggc gcaauagucu cauguuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa ccguggaaua auaaaaacau uuucuaaugg uugugacuac     1380

guaagcaaua aaggaguaga uacaguauca gucggcaaca ccuuauacug uguaaacaaa     1440

caagaaggcc aaaguuuaua cgucaaagga gaacccauca ucaacuucua cgacccauua     1500

guauucccau cagacgaauu ugaugcaagc auuucacaag ucaacgaaaa aaucaaucaa     1560

ucauuagcau ucauccgaaa aucagacgaa uuauuacaca acguaaacgc cggaaaauca     1620

accacuaaua uaaugauaac cacaauaauc aucguaauaa uaguaauacu ucucucacua     1680

aucgcagucg gacuccuucu auacugcaaa gcaagaucua caccaguaac acuauccaaa     1740

gaucaacuaa guggcauaaa caacauagca uuuucuaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2702
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2702
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uaaaagccaa cgcgaucacc acaauccuga cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaagaguuc uaccaaucca caugcuccgc cgucuccaag      300

ggcuaccugg gcgcacuucg uacaggcugg uacaccuccg uaauaaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caagcaagaa      420

cuugacaaau acaaaaaugc agucaccgac cuucaacucc ucaugcaauc uacccccgcc      480

acaggcuccg gcuccgcuau cugcuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggugaaguaa acaaaauaaa auccgcccuc cucuccacca acaaagccgu cgucucccua      600

ucaaacggcg ucuccgugcu caccuucaag guucucgacc ugaaaaacua cauagacaaa      660

cagcuccuac caauccuuaa caaacagagc ugcuccauuc cgaauaucga aacgguaauc      720

gaauuucaac agaaaaacaa ccgccuccuc gaaauaacgc gagaguucuc cguaaacgcu      780

ggcgucacca cacccgucag caccuacaug cuaacgaacu ccgaacucuu gucgcucauc      840

aacgacaugc ccauaaccaa cgaccaaaag aaacuaaugu ccaauaacgu acaaaucgua      900

cgccaacaau cuuacuccau caugugcauc auaaaagaag aaguacuagc uuacgucguc      960

caacucccac uguacggagu caucgacacc cccugcugga aacuccacac cucuccccuc     1020

ugcaccacca acaccaaaga gggcuccaac auuugccuga cacgcaccga ccgcggcugg     1080

uacugcgaca acgcaggcuc cgucucguuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga agucaaucua     1200

ugcaacguag acaucuucaa cccgaaauau gacugcaaaa uuaugacauc uaaaaccgac     1260

guguccuccu cagucaucac uucccuagga gccaucguuu ccuguuacgg caagaccaaa     1320

ugcaccgcca gcaacaaaaa ccgaggcauc aucaaaaccu ucuccaacgg augugacuau     1380

gucuccaaca agggcgucga caccgucagc gucggcaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccucua cgucaaagga gagcccauaa ucaacuucua cgacccccuc     1500

gucuucccau ccgacgaguu cgacgccuca aucucccaag ucaacgagaa aaucaaccaa     1560

uccuuagccu ucauccguaa guccgacgaa cuccuucaca acgucaacgc cgguaaaucu     1620

accaccaaca ucaugauaac aacaauaauu aucgucauca ucgucauccu ccuuucccuc     1680

aucgcggucg ggcuauugcu cuacugcaaa gcccggucca ccccaguaac ccucucuaaa     1740

gaccaacuca gcggaaucaa uaacauagcc uucagcaauu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  2703
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2703
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2704
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2704
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2705
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2705
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2706
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2706
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2707
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2707
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2708
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2708
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2709
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2709
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagcaaa cgcaauuaca acuauacuua ccgccguaac auuuugcuuc      240

gcaucugggc aaaacauuac cgaagaauuu uaucaaucaa caugcucagc agucuccaaa      300

ggauaccuug gagcauuaag aaccggcugg uauaccuccg uaauaacaau ugaacuaucu      360

aauauaaaag aaaauaaaug uaauggaacu gacgcaaaag uuaaacuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cgucacagac cuacaacuac uaaugcaauc aacccccgca      480

acaggaucag gauccgcaau cugcagcggc gucgcaguuu gcaaaguccu acauuuagaa      540

ggagaaguaa acaaaauaaa aucugcucuc cucucuacaa acaaagcagu agugucacuu      600

ucaaacggag uaucaguucu aacauucaaa guacuagacc uaaaaaauua cauagacaaa      660

caacuacuuc caauucuaaa caaacaaucc uguuccauac ccaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagacuccua gaaauuacaa gagaauuuuc cgucaaugca      780

ggaguaacaa ccccaguauc aaccuacaug uuaacuaacu cagaacucuu aucacuaaua      840

aacgacaugc caaucacuaa ugaccaaaaa aaacucaugu caaauaacgu acaaauaguc      900

cgacaacaau cauacuccau caugugcauu auaaaagaag aaguacuagc auacgucguc      960

caauuaccac uauacggcgu cauagacaca ccauguugga aacuccacac aucaccacua     1020

ugcacuacaa auacaaaaga aggcuccaac aucugccuaa caagaacaga cagagguugg     1080

uauugcgaca acgcaggauc aguaucauuu uucccccaag cagaaacaug uaaaguacaa     1140

ucaaauagag ucuucugcga caccaugaac ucauuaacac uaccuucaga agucaaccua     1200

ugcaacguag acaucuucaa cccuaaauau gacugcaaaa ucaugaccag caaaaccgac     1260

guuucaucuu ccguaauaac aucacuaggc gcaauagucu cauguuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa ccguggaaua auaaaaacau uuucuaaugg uugugacuac     1380

guaagcaaua aaggaguaga uacaguauca gucggcaaca ccuuauacug uguaaacaaa     1440

caagaaggcc aaaguuuaua cgucaaagga gaacccauca ucaacuucua cgacccauua     1500

guauucccau cagacgaauu ugaugcaagc auuucacaag ucaacgaaaa aaucaaucaa     1560

ucauuagcau ucauccgaaa aucagacgaa uuauuacaca acguaaacgc cggaaaauca     1620

accacuaaua uaaugauaac cacaauaauc aucguaauaa uaguaauacu ucucucacua     1680

aucgcagucg gacuccuucu auacugcaaa gcaagaucua caccaguaac acuauccaaa     1740

gaucaacuaa guggcauaaa caacauagca uuuucuaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2710
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2710
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uaaaagccaa cgcgaucacc acaauccuga cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaagaguuc uaccaaucca caugcuccgc cgucuccaag      300

ggcuaccugg gcgcacuucg uacaggcugg uacaccuccg uaauaaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caagcaagaa      420

cuugacaaau acaaaaaugc agucaccgac cuucaacucc ucaugcaauc uacccccgcc      480

acaggcuccg gcuccgcuau cugcuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggugaaguaa acaaaauaaa auccgcccuc cucuccacca acaaagccgu cgucucccua      600

ucaaacggcg ucuccgugcu caccuucaag guucucgacc ugaaaaacua cauagacaaa      660

cagcuccuac caauccuuaa caaacagagc ugcuccauuc cgaauaucga aacgguaauc      720

gaauuucaac agaaaaacaa ccgccuccuc gaaauaacgc gagaguucuc cguaaacgcu      780

ggcgucacca cacccgucag caccuacaug cuaacgaacu ccgaacucuu gucgcucauc      840

aacgacaugc ccauaaccaa cgaccaaaag aaacuaaugu ccaauaacgu acaaaucgua      900

cgccaacaau cuuacuccau caugugcauc auaaaagaag aaguacuagc uuacgucguc      960

caacucccac uguacggagu caucgacacc cccugcugga aacuccacac cucuccccuc     1020

ugcaccacca acaccaaaga gggcuccaac auuugccuga cacgcaccga ccgcggcugg     1080

uacugcgaca acgcaggcuc cgucucguuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga agucaaucua     1200

ugcaacguag acaucuucaa cccgaaauau gacugcaaaa uuaugacauc uaaaaccgac     1260

guguccuccu cagucaucac uucccuagga gccaucguuu ccuguuacgg caagaccaaa     1320

ugcaccgcca gcaacaaaaa ccgaggcauc aucaaaaccu ucuccaacgg augugacuau     1380

gucuccaaca agggcgucga caccgucagc gucggcaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccucua cgucaaagga gagcccauaa ucaacuucua cgacccccuc     1500

gucuucccau ccgacgaguu cgacgccuca aucucccaag ucaacgagaa aaucaaccaa     1560

uccuuagccu ucauccguaa guccgacgaa cuccuucaca acgucaacgc cgguaaaucu     1620

accaccaaca ucaugauaac aacaauaauu aucgucauca ucgucauccu ccuuucccuc     1680

aucgcggucg ggcuauugcu cuacugcaaa gcccggucca ccccaguaac ccucucuaaa     1740

gaccaacuca gcggaaucaa uaacauagcc uucagcaauu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  2711
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2711
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2712
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2712
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2713
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2713
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2714
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2714
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggauaaa caauaucgca uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2715
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2715
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2716
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2716
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaauuaa caauaucgcu uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2717
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2717
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc uaaaagcaaa cgcaauuaca acuauacuua ccgccguaac auuuugcuuc      240

gcaucugggc aaaacauuac cgaagaauuu uaucaaucaa caugcucagc agucuccaaa      300

ggauaccuug gagcauuaag aaccggcugg uauaccuccg uaauaacaau ugaacuaucu      360

aauauaaaag aaaauaaaug uaauggaacu gacgcaaaag uuaaacuaau aaaacaagaa      420

cucgacaaau acaaaaacgc cgucacagac cuacaacuac uaaugcaauc aacccccgca      480

acaggaucag gauccgcaau cugcagcggc gucgcaguuu gcaaaguccu acauuuagaa      540

ggagaaguaa acaaaauaaa aucugcucuc cucucuacaa acaaagcagu agugucacuu      600

ucaaacggag uaucaguucu aacauucaaa guacuagacc uaaaaaauua cauagacaaa      660

caacuacuuc caauucuaaa caaacaaucc uguuccauac ccaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagacuccua gaaauuacaa gagaauuuuc cgucaaugca      780

ggaguaacaa ccccaguauc aaccuacaug uuaacuaacu cagaacucuu aucacuaaua      840

aacgacaugc caaucacuaa ugaccaaaaa aaacucaugu caaauaacgu acaaauaguc      900

cgacaacaau cauacuccau caugugcauu auaaaagaag aaguacuagc auacgucguc      960

caauuaccac uauacggcgu cauagacaca ccauguugga aacuccacac aucaccacua     1020

ugcacuacaa auacaaaaga aggcuccaac aucugccuaa caagaacaga cagagguugg     1080

uauugcgaca acgcaggauc aguaucauuu uucccccaag cagaaacaug uaaaguacaa     1140

ucaaauagag ucuucugcga caccaugaac ucauuaacac uaccuucaga agucaaccua     1200

ugcaacguag acaucuucaa cccuaaauau gacugcaaaa ucaugaccag caaaaccgac     1260

guuucaucuu ccguaauaac aucacuaggc gcaauagucu cauguuacgg caaaacaaaa     1320

uguacagcau caaauaaaaa ccguggaaua auaaaaacau uuucuaaugg uugugacuac     1380

guaagcaaua aaggaguaga uacaguauca gucggcaaca ccuuauacug uguaaacaaa     1440

caagaaggcc aaaguuuaua cgucaaagga gaacccauca ucaacuucua cgacccauua     1500

guauucccau cagacgaauu ugaugcaagc auuucacaag ucaacgaaaa aaucaaucaa     1560

ucauuagcau ucauccgaaa aucagacgaa uuauuacaca acguaaacgc cggaaaauca     1620

accacuaaua uaaugauaac cacaauaauc aucguaauaa uaguaauacu ucucucacua     1680

aucgcagucg gacuccuucu auacugcaaa gcaagaucua caccaguaac acuauccaaa     1740

gaucaacuaa guggcauaaa caacauagca uuuucuaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2718
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2718
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uaaaagccaa cgcgaucacc acaauccuga cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaagaguuc uaccaaucca caugcuccgc cgucuccaag      300

ggcuaccugg gcgcacuucg uacaggcugg uacaccuccg uaauaaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caagcaagaa      420

cuugacaaau acaaaaaugc agucaccgac cuucaacucc ucaugcaauc uacccccgcc      480

acaggcuccg gcuccgcuau cugcuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggugaaguaa acaaaauaaa auccgcccuc cucuccacca acaaagccgu cgucucccua      600

ucaaacggcg ucuccgugcu caccuucaag guucucgacc ugaaaaacua cauagacaaa      660

cagcuccuac caauccuuaa caaacagagc ugcuccauuc cgaauaucga aacgguaauc      720

gaauuucaac agaaaaacaa ccgccuccuc gaaauaacgc gagaguucuc cguaaacgcu      780

ggcgucacca cacccgucag caccuacaug cuaacgaacu ccgaacucuu gucgcucauc      840

aacgacaugc ccauaaccaa cgaccaaaag aaacuaaugu ccaauaacgu acaaaucgua      900

cgccaacaau cuuacuccau caugugcauc auaaaagaag aaguacuagc uuacgucguc      960

caacucccac uguacggagu caucgacacc cccugcugga aacuccacac cucuccccuc     1020

ugcaccacca acaccaaaga gggcuccaac auuugccuga cacgcaccga ccgcggcugg     1080

uacugcgaca acgcaggcuc cgucucguuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga agucaaucua     1200

ugcaacguag acaucuucaa cccgaaauau gacugcaaaa uuaugacauc uaaaaccgac     1260

guguccuccu cagucaucac uucccuagga gccaucguuu ccuguuacgg caagaccaaa     1320

ugcaccgcca gcaacaaaaa ccgaggcauc aucaaaaccu ucuccaacgg augugacuau     1380

gucuccaaca agggcgucga caccgucagc gucggcaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccucua cgucaaagga gagcccauaa ucaacuucua cgacccccuc     1500

gucuucccau ccgacgaguu cgacgccuca aucucccaag ucaacgagaa aaucaaccaa     1560

uccuuagccu ucauccguaa guccgacgaa cuccuucaca acgucaacgc cgguaaaucu     1620

accaccaaca ucaugauaac aacaauaauu aucgucauca ucgucauccu ccuuucccuc     1680

aucgcggucg ggcuauugcu cuacugcaaa gcccggucca ccccaguaac ccucucuaaa     1740

gaccaacuca gcggaaucaa uaacauagcc uucagcaauu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2719
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2719
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2720
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2720
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1620

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2721
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2721
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2722
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2722
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      720

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg      960

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1140

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1440

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1620

aaagaucaac ucucugggau aaacaauauc gcauucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2723
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2723
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2724
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2724
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      720

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc      960

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1440

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1620

aaagaucaac ucuccggaau uaacaauauc gcuuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2725
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2725
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuaa uccuaaaagc aaacgcaauu acaacuauac uuaccgccgu aacauuuugc      120

uucgcaucug ggcaaaacau uaccgaagaa uuuuaucaau caacaugcuc agcagucucc      180

aaaggauacc uuggagcauu aagaaccggc ugguauaccu ccguaauaac aauugaacua      240

ucuaauauaa aagaaaauaa auguaaugga acugacgcaa aaguuaaacu aauaaaacaa      300

gaacucgaca aauacaaaaa cgccgucaca gaccuacaac uacuaaugca aucaaccccc      360

gcaacaggau caggauccgc aaucugcagc ggcgucgcag uuugcaaagu ccuacauuua      420

gaaggagaag uaaacaaaau aaaaucugcu cuccucucua caaacaaagc aguaguguca      480

cuuucaaacg gaguaucagu ucuaacauuc aaaguacuag accuaaaaaa uuacauagac      540

aaacaacuac uuccaauucu aaacaaacaa uccuguucca uacccaacau agaaacagua      600

auagaauuuc aacaaaaaaa uaacagacuc cuagaaauua caagagaauu uuccgucaau      660

gcaggaguaa caaccccagu aucaaccuac auguuaacua acucagaacu cuuaucacua      720

auaaacgaca ugccaaucac uaaugaccaa aaaaaacuca ugucaaauaa cguacaaaua      780

guccgacaac aaucauacuc caucaugugc auuauaaaag aagaaguacu agcauacguc      840

guccaauuac cacuauacgg cgucauagac acaccauguu ggaaacucca cacaucacca      900

cuaugcacua caaauacaaa agaaggcucc aacaucugcc uaacaagaac agacagaggu      960

ugguauugcg acaacgcagg aucaguauca uuuuuccccc aagcagaaac auguaaagua     1020

caaucaaaua gagucuucug cgacaccaug aacucauuaa cacuaccuuc agaagucaac     1080

cuaugcaacg uagacaucuu caacccuaaa uaugacugca aaaucaugac cagcaaaacc     1140

gacguuucau cuuccguaau aacaucacua ggcgcaauag ucucauguua cggcaaaaca     1200

aaauguacag caucaaauaa aaaccgugga auaauaaaaa cauuuucuaa ugguugugac     1260

uacguaagca auaaaggagu agauacagua ucagucggca acaccuuaua cuguguaaac     1320

aaacaagaag gccaaaguuu auacgucaaa ggagaaccca ucaucaacuu cuacgaccca     1380

uuaguauucc caucagacga auuugaugca agcauuucac aagucaacga aaaaaucaau     1440

caaucauuag cauucauccg aaaaucagac gaauuauuac acaacguaaa cgccggaaaa     1500

ucaaccacua auauaaugau aaccacaaua aucaucguaa uaauaguaau acuucucuca     1560

cuaaucgcag ucggacuccu ucuauacugc aaagcaagau cuacaccagu aacacuaucc     1620

aaagaucaac uaaguggcau aaacaacaua gcauuuucua acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2726
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2726
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccuaaaagc caacgcgauc accacaaucc ugacagccgu caccuucugc      120

uucgccuccg gccaaaacau caccgaagag uucuaccaau ccacaugcuc cgccgucucc      180

aagggcuacc ugggcgcacu ucguacaggc ugguacaccu ccguaauaac caucgaacuc      240

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaagcaa      300

gaacuugaca aauacaaaaa ugcagucacc gaccuucaac uccucaugca aucuaccccc      360

gccacaggcu ccggcuccgc uaucugcucc ggcgucgccg ucugcaaagu ccuccaccuc      420

gaaggugaag uaaacaaaau aaaauccgcc cuccucucca ccaacaaagc cgucgucucc      480

cuaucaaacg gcgucuccgu gcucaccuuc aagguucucg accugaaaaa cuacauagac      540

aaacagcucc uaccaauccu uaacaaacag agcugcucca uuccgaauau cgaaacggua      600

aucgaauuuc aacagaaaaa caaccgccuc cucgaaauaa cgcgagaguu cuccguaaac      660

gcuggcguca ccacacccgu cagcaccuac augcuaacga acuccgaacu cuugucgcuc      720

aucaacgaca ugcccauaac caacgaccaa aagaaacuaa uguccaauaa cguacaaauc      780

guacgccaac aaucuuacuc caucaugugc aucauaaaag aagaaguacu agcuuacguc      840

guccaacucc cacuguacgg agucaucgac acccccugcu ggaaacucca caccucuccc      900

cucugcacca ccaacaccaa agagggcucc aacauuugcc ugacacgcac cgaccgcggc      960

ugguacugcg acaacgcagg cuccgucucg uucuuccccc aagccgaaac cugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaagucaau     1080

cuaugcaacg uagacaucuu caacccgaaa uaugacugca aaauuaugac aucuaaaacc     1140

gacguguccu ccucagucau cacuucccua ggagccaucg uuuccuguua cggcaagacc     1200

aaaugcaccg ccagcaacaa aaaccgaggc aucaucaaaa ccuucuccaa cggaugugac     1260

uaugucucca acaagggcgu cgacaccguc agcgucggca acacccucua cugcgucaac     1320

aaacaagaag gccaaucccu cuacgucaaa ggagagccca uaaucaacuu cuacgacccc     1380

cucgucuucc cauccgacga guucgacgcc ucaaucuccc aagucaacga gaaaaucaac     1440

caauccuuag ccuucauccg uaaguccgac gaacuccuuc acaacgucaa cgccgguaaa     1500

ucuaccacca acaucaugau aacaacaaua auuaucguca ucaucgucau ccuccuuucc     1560

cucaucgcgg ucgggcuauu gcucuacugc aaagcccggu ccaccccagu aacccucucu     1620

aaagaccaac ucagcggaau caauaacaua gccuucagca auuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2727
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2727
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc cuguccaagg     1620

accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2728
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2728
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug gucagccucu      480

ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug agccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac cggggcuggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag gucaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc gucaacaagc     1320

aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac gacccccugg     1380

uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc cugagcaagg     1620

accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2729
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2729
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc cucuccaagg     1620

accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2730
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2730
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug caccucgagg      420

gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug gucucccucu      480

cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac auugacaaac      540

aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu gucaacgccg      660

gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug ucccucauca      720

acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc cagaucguuc      780

gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg uauguagugc      840

aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca ucuccccugu      900

gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac cguggguggu      960

acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu aagguucagu     1020

cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa gucaaucucu     1080

gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu aaaacagaug     1140

uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc aagaccaaau     1200

guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga ugcgacuaug     1260

ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu guuaacaagc     1320

aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac gauccauugg     1380

uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag aucaaccagu     1440

cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc ggcaagagca     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaucccuca     1560

ucgcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc cugaguaaag     1620

aucaacucuc ugggauaaac aauaucgcau ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2731
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2731
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc cugagcaagg     1620

accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2732
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2732
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc caccuggagg      420

gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc gugucucucu      480

ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac auugacaaac      540

aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc gugaacgcug      660

gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc agccugauca      720

acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug cagaucguga      780

gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc uaugugguuc      840

aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg agcccccucu      900

gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac cgcggcuggu      960

acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu aaggugcaga     1020

gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa gugaaucucu     1080

gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc aaaacagaug     1140

ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc aagacaaaau     1200

guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga ugcgacuaug     1260

uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu guuaacaagc     1320

aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac gauccccucg     1380

ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag auuaaccagu     1440

cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu ggcaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucccuga     1560

ucgccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc cuuucuaaag     1620

aucaacucuc cggaauuaac aauaucgcuu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2733
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2733
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacuaauccu aaaagcaaac gcaauuacaa cuauacuuac cgccguaaca uuuugcuucg      120

caucugggca aaacauuacc gaagaauuuu aucaaucaac augcucagca gucuccaaag      180

gauaccuugg agcauuaaga accggcuggu auaccuccgu aauaacaauu gaacuaucua      240

auauaaaaga aaauaaaugu aauggaacug acgcaaaagu uaaacuaaua aaacaagaac      300

ucgacaaaua caaaaacgcc gucacagacc uacaacuacu aaugcaauca acccccgcaa      360

caggaucagg auccgcaauc ugcagcggcg ucgcaguuug caaaguccua cauuuagaag      420

gagaaguaaa caaaauaaaa ucugcucucc ucucuacaaa caaagcagua gugucacuuu      480

caaacggagu aucaguucua acauucaaag uacuagaccu aaaaaauuac auagacaaac      540

aacuacuucc aauucuaaac aaacaauccu guuccauacc caacauagaa acaguaauag      600

aauuucaaca aaaaaauaac agacuccuag aaauuacaag agaauuuucc gucaaugcag      660

gaguaacaac cccaguauca accuacaugu uaacuaacuc agaacucuua ucacuaauaa      720

acgacaugcc aaucacuaau gaccaaaaaa aacucauguc aaauaacgua caaauagucc      780

gacaacaauc auacuccauc augugcauua uaaaagaaga aguacuagca uacgucgucc      840

aauuaccacu auacggcguc auagacacac cauguuggaa acuccacaca ucaccacuau      900

gcacuacaaa uacaaaagaa ggcuccaaca ucugccuaac aagaacagac agagguuggu      960

auugcgacaa cgcaggauca guaucauuuu ucccccaagc agaaacaugu aaaguacaau     1020

caaauagagu cuucugcgac accaugaacu cauuaacacu accuucagaa gucaaccuau     1080

gcaacguaga caucuucaac ccuaaauaug acugcaaaau caugaccagc aaaaccgacg     1140

uuucaucuuc cguaauaaca ucacuaggcg caauagucuc auguuacggc aaaacaaaau     1200

guacagcauc aaauaaaaac cguggaauaa uaaaaacauu uucuaauggu ugugacuacg     1260

uaagcaauaa aggaguagau acaguaucag ucggcaacac cuuauacugu guaaacaaac     1320

aagaaggcca aaguuuauac gucaaaggag aacccaucau caacuucuac gacccauuag     1380

uauucccauc agacgaauuu gaugcaagca uuucacaagu caacgaaaaa aucaaucaau     1440

cauuagcauu cauccgaaaa ucagacgaau uauuacacaa cguaaacgcc ggaaaaucaa     1500

ccacuaauau aaugauaacc acaauaauca ucguaauaau aguaauacuu cucucacuaa     1560

ucgcagucgg acuccuucua uacugcaaag caagaucuac accaguaaca cuauccaaag     1620

aucaacuaag uggcauaaac aacauagcau uuucuaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2734
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2734
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu aaaagccaac gcgaucacca caauccugac agccgucacc uucugcuucg      120

ccuccggcca aaacaucacc gaagaguucu accaauccac augcuccgcc gucuccaagg      180

gcuaccuggg cgcacuucgu acaggcuggu acaccuccgu aauaaccauc gaacucucca      240

acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc aagcaagaac      300

uugacaaaua caaaaaugca gucaccgacc uucaacuccu caugcaaucu acccccgcca      360

caggcuccgg cuccgcuauc ugcuccggcg ucgccgucug caaaguccuc caccucgaag      420

gugaaguaaa caaaauaaaa uccgcccucc ucuccaccaa caaagccguc gucucccuau      480

caaacggcgu cuccgugcuc accuucaagg uucucgaccu gaaaaacuac auagacaaac      540

agcuccuacc aauccuuaac aaacagagcu gcuccauucc gaauaucgaa acgguaaucg      600

aauuucaaca gaaaaacaac cgccuccucg aaauaacgcg agaguucucc guaaacgcug      660

gcgucaccac acccgucagc accuacaugc uaacgaacuc cgaacucuug ucgcucauca      720

acgacaugcc cauaaccaac gaccaaaaga aacuaauguc caauaacgua caaaucguac      780

gccaacaauc uuacuccauc augugcauca uaaaagaaga aguacuagcu uacgucgucc      840

aacucccacu guacggaguc aucgacaccc ccugcuggaa acuccacacc ucuccccucu      900

gcaccaccaa caccaaagag ggcuccaaca uuugccugac acgcaccgac cgcggcuggu      960

acugcgacaa cgcaggcucc gucucguucu ucccccaagc cgaaaccugc aaaguccaau     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgaa gucaaucuau     1080

gcaacguaga caucuucaac ccgaaauaug acugcaaaau uaugacaucu aaaaccgacg     1140

uguccuccuc agucaucacu ucccuaggag ccaucguuuc cuguuacggc aagaccaaau     1200

gcaccgccag caacaaaaac cgaggcauca ucaaaaccuu cuccaacgga ugugacuaug     1260

ucuccaacaa gggcgucgac accgucagcg ucggcaacac ccucuacugc gucaacaaac     1320

aagaaggcca aucccucuac gucaaaggag agcccauaau caacuucuac gacccccucg     1380

ucuucccauc cgacgaguuc gacgccucaa ucucccaagu caacgagaaa aucaaccaau     1440

ccuuagccuu cauccguaag uccgacgaac uccuucacaa cgucaacgcc gguaaaucua     1500

ccaccaacau caugauaaca acaauaauua ucgucaucau cgucauccuc cuuucccuca     1560

ucgcggucgg gcuauugcuc uacugcaaag cccgguccac cccaguaacc cucucuaaag     1620

accaacucag cggaaucaau aacauagccu ucagcaauua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  2735
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1) R6772

<400>  2735
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccggagc     1560

acgcccguca cccuguccaa ggaccagcug agcggcauca acaacaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2736
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt1)

<400>  2736
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucugcuccgg cguggccgug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcgcu gcuguccacc      420

aacaaggccg uggucagccu cuccaacggc gugagcgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcaguc cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcucaccaac      660

uccgagcugc ugagccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccg cuguacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggguccaa caucugccug      900

acccgcaccg accggggcug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cucccguccg aggucaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccucuacu gcgucaacaa gcaggagggc cagagccugu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccccu gguguucccg agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cgggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug gggcuccugc uguacugcaa ggcccggucc     1560

acccccguga cccugagcaa ggaccagcuc uccggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2737
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt2)

<400>  2737
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcucc     1560

acccccguca cccucuccaa ggaccagcuc uccggcauca acaacaucgc cuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2738
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt3)

<400>  2738
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga ccugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua uauguucagg cguggcaguc      360

ugcaaggugu ugcaccucga gggugagguu aacaaaauca agagcgcccu gcugaguacg      420

aauaaagcug uggucucccu cucuaacggg gugagcguau uaacuuuuaa gguucuggau      480

cuuaagaauu acauugacaa acaauugcug ccuauccuaa acaagcaguc cuguucaauu      540

ccaaauaucg aaaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuua gugucaacgc cggagugacu accccgguga gcacauauau gcuuaccaau      660

ucugagcugu ugucccucau caacgauaug cccauuacga acgaccaaaa gaaacugaug      720

ucaaauaacg uccagaucgu ucgccagcag agcuacagua ucaugugcau uauaaaggaa      780

gagguguuag cguauguagu gcaacugccu cucuacggcg ucaucgauac uccauguugg      840

aaacuucaua caucuccccu gugcaccacu aauacaaagg aaggcuccaa cauuuguuug      900

acccgaacgg accgugggug guacugcgau aaugcaggaa gcgugucguu cuuuccucag      960

gccgagaccu guaagguuca gucuaacaga guguucugcg acacaaugaa cucccuaacu     1020

cugccaucag aagucaaucu cugcaaugug gauaucuuua accccaaaua ugacuguaag     1080

auaaugacca guaaaacaga uguaagcucc ucuguuauua cuagccuggg ugcuaucgug     1140

ucaugcuacg gcaagaccaa auguacagcc aguaauaaga acagggggau cauuaagacc     1200

uucuccaaug gaugcgacua ugucagcaac aaaggcgugg acacugucuc uguggguaau     1260

acgcuuuacu guguuaacaa gcaagagggg cagucacugu augugaaagg agagccuauc     1320

auuaacuuuu acgauccauu gguauucccg agugacgaau uugaugcaag cauaucccag     1380

gucaaugaga agaucaacca gucucucgcu uucauucgga aaucggacga acuguuacac     1440

aaugugaacg ccggcaagag cacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaucccu caucgcgguc ggccugcuuu uguauugcaa ggcccgcuca     1560

acacccguga cccugaguaa agaucaacuc ucugggauaa acaauaucgc auucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2739
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt4)

<400>  2739
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagaagc     1560

acccccguga cccugagcaa ggaccagcug agcggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2740
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt5)

<400>  2740
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaauaaau gcaacgggac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga ccuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua uuuguagcgg ggucgccgug      360

ugcaagguuc uccaccugga gggagaggug aacaaaauca aguccgcgcu ucugagcacc      420

aauaaagccg ucgugucucu cuccaacggc guuagcgugc ugacauuuaa gguccuugau      480

cugaagaauu acauugacaa acaacuccug ccuauccuga acaagcaguc uuguuccauu      540

ccgaauaucg aaaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuua gcgugaacgc uggcgucaca acccccguuu cuacauauau gcuuaccaau      660

uccgagcugc ucagccugau caacgauaug ccuauuacca acgaccaaaa gaaacuuaug      720

uccaauaacg ugcagaucgu gagacagcag ucuuacagca uuaugugcau cauuaaggaa      780

gagguccugg ccuauguggu ucaacucccc cuguacgggg ugaucgauac accuuguugg      840

aaacugcaua cgagcccccu cugcaccaca aauaccaagg aaggauccaa caucugucug      900

acacggaccg accgcggcug guacugcgau aaugcugggu cugucuccuu cuuuccucag      960

gccgagacgu guaaggugca gagcaacaga guuuucugcg acacaaugaa cucucuuacc     1020

cugccgagcg aagugaaucu cugcaauguc gauauuuuua accccaaaua ugacuguaag     1080

aucaugaccu ccaaaacaga ugugucuagc uccgucauua ccagccuggg agcgaucgug     1140

ucuugcuacg gcaagacaaa auguacggcc uccaauaaga accgggggau uaucaagacc     1200

uucagcaaug gaugcgacua uguuucuaac aaaggcgugg acacagucuc cgugggcaau     1260

acccuuuacu guguuaacaa gcaagagggg cagagccugu augugaaagg agagccuauc     1320

auuaacuuuu acgauccccu cgucuucccu uccgacgaau uugaugcuuc uaucagccag     1380

gugaaugaga agauuaacca gucccuggcc uucauccgca aaucugacga acugcuccac     1440

aaugugaacg cuggcaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucccu gaucgccgug gggcuccugc uguauugcaa ggccagaagc     1560

acacccguga cccuuucuaa agaucaacuc uccggaauua acaauaucgc uuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2741
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt6)

<400>  2741
gggagaaagc uuaccaugga acuacuaauc cuaaaagcaa acgcaauuac aacuauacuu       60

accgccguaa cauuuugcuu cgcaucuggg caaaacauua ccgaagaauu uuaucaauca      120

acaugcucag cagucuccaa aggauaccuu ggagcauuaa gaaccggcug guauaccucc      180

guaauaacaa uugaacuauc uaauauaaaa gaaaauaaau guaauggaac ugacgcaaaa      240

guuaaacuaa uaaaacaaga acucgacaaa uacaaaaacg ccgucacaga ccuacaacua      300

cuaaugcaau caacccccgc aacaggauca ggauccgcaa ucugcagcgg cgucgcaguu      360

ugcaaagucc uacauuuaga aggagaagua aacaaaauaa aaucugcucu ccucucuaca      420

aacaaagcag uagugucacu uucaaacgga guaucaguuc uaacauucaa aguacuagac      480

cuaaaaaauu acauagacaa acaacuacuu ccaauucuaa acaaacaauc cuguuccaua      540

cccaacauag aaacaguaau agaauuucaa caaaaaaaua acagacuccu agaaauuaca      600

agagaauuuu ccgucaaugc aggaguaaca accccaguau caaccuacau guuaacuaac      660

ucagaacucu uaucacuaau aaacgacaug ccaaucacua augaccaaaa aaaacucaug      720

ucaaauaacg uacaaauagu ccgacaacaa ucauacucca ucaugugcau uauaaaagaa      780

gaaguacuag cauacgucgu ccaauuacca cuauacggcg ucauagacac accauguugg      840

aaacuccaca caucaccacu augcacuaca aauacaaaag aaggcuccaa caucugccua      900

acaagaacag acagagguug guauugcgac aacgcaggau caguaucauu uuucccccaa      960

gcagaaacau guaaaguaca aucaaauaga gucuucugcg acaccaugaa cucauuaaca     1020

cuaccuucag aagucaaccu augcaacgua gacaucuuca acccuaaaua ugacugcaaa     1080

aucaugacca gcaaaaccga cguuucaucu uccguaauaa caucacuagg cgcaauaguc     1140

ucauguuacg gcaaaacaaa auguacagca ucaaauaaaa accguggaau aauaaaaaca     1200

uuuucuaaug guugugacua cguaagcaau aaaggaguag auacaguauc agucggcaac     1260

accuuauacu guguaaacaa acaagaaggc caaaguuuau acgucaaagg agaacccauc     1320

aucaacuucu acgacccauu aguauuccca ucagacgaau uugaugcaag cauuucacaa     1380

gucaacgaaa aaaucaauca aucauuagca uucauccgaa aaucagacga auuauuacac     1440

aacguaaacg ccggaaaauc aaccacuaau auaaugauaa ccacaauaau caucguaaua     1500

auaguaauac uucucucacu aaucgcaguc ggacuccuuc uauacugcaa agcaagaucu     1560

acaccaguaa cacuauccaa agaucaacua aguggcauaa acaacauagc auuuucuaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2742
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut2 (opt11)

<400>  2742
gggagaaagc uuaccaugga acuccucauc cuaaaagcca acgcgaucac cacaauccug       60

acagccguca ccuucugcuu cgccuccggc caaaacauca ccgaagaguu cuaccaaucc      120

acaugcuccg ccgucuccaa gggcuaccug ggcgcacuuc guacaggcug guacaccucc      180

guaauaacca ucgaacucuc caacaucaaa gaaaacaaau gcaacggcac agacgcaaaa      240

gucaaacuca ucaagcaaga acuugacaaa uacaaaaaug cagucaccga ccuucaacuc      300

cucaugcaau cuacccccgc cacaggcucc ggcuccgcua ucugcuccgg cgucgccguc      360

ugcaaagucc uccaccucga aggugaagua aacaaaauaa aauccgcccu ccucuccacc      420

aacaaagccg ucgucucccu aucaaacggc gucuccgugc ucaccuucaa gguucucgac      480

cugaaaaacu acauagacaa acagcuccua ccaauccuua acaaacagag cugcuccauu      540

ccgaauaucg aaacgguaau cgaauuucaa cagaaaaaca accgccuccu cgaaauaacg      600

cgagaguucu ccguaaacgc uggcgucacc acacccguca gcaccuacau gcuaacgaac      660

uccgaacucu ugucgcucau caacgacaug cccauaacca acgaccaaaa gaaacuaaug      720

uccaauaacg uacaaaucgu acgccaacaa ucuuacucca ucaugugcau cauaaaagaa      780

gaaguacuag cuuacgucgu ccaacuccca cuguacggag ucaucgacac ccccugcugg      840

aaacuccaca ccucuccccu cugcaccacc aacaccaaag agggcuccaa cauuugccug      900

acacgcaccg accgcggcug guacugcgac aacgcaggcu ccgucucguu cuucccccaa      960

gccgaaaccu gcaaagucca auccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aagucaaucu augcaacgua gacaucuuca acccgaaaua ugacugcaaa     1080

auuaugacau cuaaaaccga cguguccucc ucagucauca cuucccuagg agccaucguu     1140

uccuguuacg gcaagaccaa augcaccgcc agcaacaaaa accgaggcau caucaaaacc     1200

uucuccaacg gaugugacua ugucuccaac aagggcgucg acaccgucag cgucggcaac     1260

acccucuacu gcgucaacaa acaagaaggc caaucccucu acgucaaagg agagcccaua     1320

aucaacuucu acgacccccu cgucuuccca uccgacgagu ucgacgccuc aaucucccaa     1380

gucaacgaga aaaucaacca auccuuagcc uucauccgua aguccgacga acuccuucac     1440

aacgucaacg ccgguaaauc uaccaccaac aucaugauaa caacaauaau uaucgucauc     1500

aucgucaucc uccuuucccu caucgcgguc gggcuauugc ucuacugcaa agcccggucc     1560

accccaguaa cccucucuaa agaccaacuc agcggaauca auaacauagc cuucagcaau     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  2743
<211>  514
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2743

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg 
        


<210>  2744
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2744
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc gguga                     1545


<210>  2745
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2745
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucugc uccggcgugg ccgugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcgcugcugu ccaccaacaa ggccgugguc      420

agccucucca acggcgugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccgcugua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      900

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu cuacugcguc     1260

aacaagcagg agggccagag ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguga                     1545


<210>  2746
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2746
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuga                     1545


<210>  2747
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2747
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugaccugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuauaugu ucaggcgugg cagucugcaa gguguugcac      360

cucgagggug agguuaacaa aaucaagagc gcccugcuga guacgaauaa agcugugguc      420

ucccucucua acggggugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauu      480

gacaaacaau ugcugccuau ccuaaacaag caguccuguu caauuccaaa uaucgaaacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuaguguc      600

aacgccggag ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      660

cucaucaacg auaugcccau uacgaacgac caaaagaaac ugaugucaaa uaacguccag      720

aucguucgcc agcagagcua caguaucaug ugcauuauaa aggaagaggu guuagcguau      780

guagugcaac ugccucucua cggcgucauc gauacuccau guuggaaacu ucauacaucu      840

ccccugugca ccacuaauac aaaggaaggc uccaacauuu guuugacccg aacggaccgu      900

gggugguacu gcgauaaugc aggaagcgug ucguucuuuc cucaggccga gaccuguaag      960

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1020

aaucucugca auguggauau cuuuaacccc aaauaugacu guaagauaau gaccaguaaa     1080

acagauguaa gcuccucugu uauuacuagc cugggugcua ucgugucaug cuacggcaag     1140

accaaaugua cagccaguaa uaagaacagg gggaucauua agaccuucuc caauggaugc     1200

gacuauguca gcaacaaagg cguggacacu gucucugugg guaauacgcu uuacuguguu     1260

aacaagcaag aggggcaguc acuguaugug aaaggagagc cuaucauuaa cuuuuacgau     1320

ccauugguau ucccgaguga cgaauuugau gcaagcauau cccaggucaa ugagaagauc     1380

aaccagucuc ucgcuuucau ucggaaaucg gacgaacugu uacacaaugu gaacgccggc     1440

aagagcacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

ucccucaucg cggucggccu gcuuuuguau ugcaaggccc gcuga                     1545


<210>  2748
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2748
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gauga                     1545


<210>  2749
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2749
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagaa uaaaugcaac gggaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggaccucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuauuugu agcggggucg ccgugugcaa gguucuccac      360

cuggagggag aggugaacaa aaucaagucc gcgcuucuga gcaccaauaa agccgucgug      420

ucucucucca acggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauu      480

gacaaacaac uccugccuau ccugaacaag cagucuuguu ccauuccgaa uaucgaaacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      600

aacgcuggcg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      660

cugaucaacg auaugccuau uaccaacgac caaaagaaac uuauguccaa uaacgugcag      720

aucgugagac agcagucuua cagcauuaug ugcaucauua aggaagaggu ccuggccuau      780

gugguucaac ucccccugua cggggugauc gauacaccuu guuggaaacu gcauacgagc      840

ccccucugca ccacaaauac caaggaagga uccaacaucu gucugacacg gaccgaccgc      900

ggcugguacu gcgauaaugc ugggucuguc uccuucuuuc cucaggccga gacguguaag      960

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1020

aaucucugca augucgauau uuuuaacccc aaauaugacu guaagaucau gaccuccaaa     1080

acagaugugu cuagcuccgu cauuaccagc cugggagcga ucgugucuug cuacggcaag     1140

acaaaaugua cggccuccaa uaagaaccgg gggauuauca agaccuucag caauggaugc     1200

gacuauguuu cuaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuguguu     1260

aacaagcaag aggggcagag ccuguaugug aaaggagagc cuaucauuaa cuuuuacgau     1320

ccccucgucu ucccuuccga cgaauuugau gcuucuauca gccaggugaa ugagaagauu     1380

aaccaguccc uggccuucau ccgcaaaucu gacgaacugc uccacaaugu gaacgcuggc     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucccugaucg ccguggggcu ccugcuguau ugcaaggcca gauga                     1545


<210>  2750
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2750
auggaacucc uaauacuuaa agccaaugca auaaccacaa uacuaacagc aguaacauuc       60

ugcuuugcau caggacaaaa cauaacagaa gaauuuuacc aaucaacaug uucagcagua      120

agcaaaggau accuaggagc cuuacgcaca gguugguaca cuuccguaau aacaauagaa      180

cucucaaaua uaaaagaaaa caaaugcaac ggaaccgaug caaaaguaaa acuaauaaaa      240

caagaauuag acaaauacaa aaacgcagua acagaccuac aauuacuuau gcaaucaaca      300

cccgcaacag gauccggcuc agcaaucugu ucaggaguag caguaugcaa aguucuccac      360

cuagaaggcg aaguaaacaa aauaaaauca gcccuauuau cuaccaauaa agcaguagua      420

ucacuaucaa auggaguauc uguccuaacc uucaaaguac uugaccuaaa aaauuacauc      480

gacaaacaau uacuaccaau acuuaacaaa caaucauguu caauaccaaa cauugaaaca      540

guaauagaau uucaacaaaa aaauaacaga uuauuagaaa uaacccgcga auuuucaguu      600

aacgcaggag uaacaacacc aguauccaca uacauguuaa caaauucaga acucuuauca      660

cuuauaaacg acaugcccau aacaaacgac caaaaaaaac ucaugucuaa caauguucaa      720

auaguucgac aacaaucaua cuccauaaug ugcauaauaa aagaagaagu ucuagcauau      780

guuguacaac ucccacucua ugguguuaua gacacaccau gcuggaaacu acauacaagc      840

cccuuaugca cuacaaacac aaaagaaggc ucuaauauau gucuaacccg cacagacaga      900

ggcugguauu gcgauaacgc agguucagua ucauucuuuc cacaagcaga aacuugcaaa      960

guccaaucca auagagucuu cugcgacacu augaacucac ucacacuccc aucugaaguc     1020

aauuuaugua acgucgauau cuucaaccca aaauacgacu gcaaaauaau gaccucaaaa     1080

acagacguaa gcucaucagu cauaacuucu cuaggcgcaa ucgucucaug uuacggcaaa     1140

acaaaaugua ccgcaucaaa caaaaaucga gguauaauaa aaaccuuuuc uaacggcugc     1200

gacuacguau caaacaaagg aguagauacu guaagugucg gaaacacauu auacugcguc     1260

aacaaacaag aaggacaauc ccuauauguu aaaggcgaac cuaucauuaa uuucuacgac     1320

ccacucgucu uuccauccga cgaauuugac gcaucaauuu cccaaguaaa ugaaaaaaua     1380

aaccaauccc uugcauucau aagaaaauca gaugaacuau uacacaacgu aaacgcaggc     1440

aaaucaacaa caaauauaau gaucacaaca auaauaaucg uaauaauagu aauccuacuc     1500

ucacuaauag caguaggcuu acuauuauau ugcaaagcca gauaa                     1545


<210>  2751
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut2

<400>  2751
auggaacuuc uuauccuaaa agcgaacgcc auaaccacaa uccuaacagc agucaccuuc       60

uguuucgccu caggacaaaa caucaccgag gaauuuuacc aauccacaug uagcgcuguc      120

ucaaaaggcu accucggcgc ccuccgaacc ggcugguaca cauccguaau aacgaucgaa      180

cucuccaaca uaaaagaaaa uaaaugcaac ggcaccgacg ccaaagucaa acuuaucaaa      240

caagaacuag acaaauacaa aaacgccguc accgaccucc agcuccucau gcaauccacc      300

ccagcaacag gcuccggaag cgcaaucugc ucaggcgucg ccguaugcaa aguacuccac      360

cucgaaggag aagucaacaa aaucaaaucc gcccuccuau ccacaaacaa agcaguuguc      420

ucacucucca acgggguaag cguacugacc uucaaagucc uagaccucaa aaacuacauc      480

gauaaacaac uccuuccaau ccucaacaaa caaucaugcu cuauccccaa caucgaaacc      540

guaaucgaau uucaacaaaa aaacaaccgc cuacuugaaa ucacacgcga auuuagcguc      600

aacgcaggag uaacaacacc cguguccaca uauaugcuca cgaacagcga acuacuaucc      660

cugauuaacg acaugcccau caccaacgac caaaaaaaac uaaugagcaa caacguacaa      720

aucguccgcc aacaaagcua cucuauaaug ugcaucauca aggaagaagu ccuagccuac      780

gucguccaau uaccacucua cggcgucauc gacacacccu gcuggaaacu ccauacaucc      840

ccccucugca ccaccaacac caaagaaggg uccaacauau gccucacucg cacagaccgc      900

ggcugguacu gcgacaacgc uggcagcguc agcuucuucc cccaggccga aaccugcaaa      960

guccaaucca acagagucuu cugcgacacc augaacucgc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau auucaacccc aaauacgacu gcaaaaucau gaccuccaaa     1080

accgacguca gcucaucagu caucacaucc cucggggcca ucgucuccug cuacggcaaa     1140

accaagugca ccgccucaaa caaaaaccgc ggcauuauca aaacauucuc caacggcugc     1200

gacuacgucu ccaacaaagg cgucgacaca gucuccgucg guaacacccu cuacugcgua     1260

aauaaacaag aaggccaauc ccucuacguc aaaggcgaac ccaucaucaa cuucuacgac     1320

ccucucgucu uccccuccga cgaauuugac gccucaauca gccaaguuaa cgaaaaaauc     1380

aaccaaucac ucgccuucau ccgcaaaucc gacgaacucc uccacaacgu uaacgccggc     1440

aaaucuacca cgaacaucau gaucaccacc auaaucaucg uaauuaucgu aauacuccua     1500

ucccucauag caguaggccu ccuacucuac ugcaaagccc guuaa                     1545


<210>  2752
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2752
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2753
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2753
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2754
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2754
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2755
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2755
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2756
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2756
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2757
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2757
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2758
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2758
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuuaaagc caaugcaaua accacaauac      120

uaacagcagu aacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

caacauguuc agcaguaagc aaaggauacc uaggagccuu acgcacaggu ugguacacuu      240

ccguaauaac aauagaacuc ucaaauauaa aagaaaacaa augcaacgga accgaugcaa      300

aaguaaaacu aauaaaacaa gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau      360

uacuuaugca aucaacaccc gcaacaggau ccggcucagc aaucuguuca ggaguagcag      420

uaugcaaagu ucuccaccua gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua      480

ccaauaaagc aguaguauca cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug      540

accuaaaaaa uuacaucgac aaacaauuac uaccaauacu uaacaaacaa ucauguucaa      600

uaccaaacau ugaaacagua auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa      660

cccgcgaauu uucaguuaac gcaggaguaa caacaccagu auccacauac auguuaacaa      720

auucagaacu cuuaucacuu auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa uguucaaaua guucgacaac aaucauacuc cauaaugugc auaauaaaag      840

aagaaguucu agcauauguu guacaacucc cacucuaugg uguuauagac acaccaugcu      900

ggaaacuaca uacaagcccc uuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacccgcac agacagaggc ugguauugcg auaacgcagg uucaguauca uucuuuccac     1020

aagcagaaac uugcaaaguc caauccaaua gagucuucug cgacacuaug aacucacuca     1080

cacucccauc ugaagucaau uuauguaacg ucgauaucuu caacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguaagcu caucagucau aacuucucua ggcgcaaucg     1200

ucucauguua cggcaaaaca aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa     1260

ccuuuucuaa cggcugcgac uacguaucaa acaaaggagu agauacugua agugucggaa     1320

acacauuaua cugcgucaac aaacaagaag gacaaucccu auauguuaaa ggcgaaccua     1380

ucauuaauuu cuacgaccca cucgucuuuc cauccgacga auuugacgca ucaauuuccc     1440

aaguaaauga aaaaauaaac caaucccuug cauucauaag aaaaucagau gaacuauuac     1500

acaacguaaa cgcaggcaaa ucaacaacaa auauaaugau cacaacaaua auaaucguaa     1560

uaauaguaau ccuacucuca cuaauagcag uaggcuuacu auuauauugc aaagccagau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2759
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2759
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuua uccuaaaagc gaacgccaua accacaaucc      120

uaacagcagu caccuucugu uucgccucag gacaaaacau caccgaggaa uuuuaccaau      180

ccacauguag cgcugucuca aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau      240

ccguaauaac gaucgaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcca      300

aagucaaacu uaucaaacaa gaacuagaca aauacaaaaa cgccgucacc gaccuccagc      360

uccucaugca auccacccca gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg      420

uaugcaaagu acuccaccuc gaaggagaag ucaacaaaau caaauccgcc cuccuaucca      480

caaacaaagc aguugucuca cucuccaacg ggguaagcgu acugaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacucc uuccaauccu caacaaacaa ucaugcucua      600

uccccaacau cgaaaccgua aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca      660

cacgcgaauu uagcgucaac gcaggaguaa caacacccgu guccacauau augcucacga      720

acagcgaacu acuaucccug auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa      780

ugagcaacaa cguacaaauc guccgccaac aaagcuacuc uauaaugugc aucaucaagg      840

aagaaguccu agccuacguc guccaauuac cacucuacgg cgucaucgac acacccugcu      900

ggaaacucca uacauccccc cucugcacca ccaacaccaa agaagggucc aacauaugcc      960

ucacucgcac agaccgcggc ugguacugcg acaacgcugg cagcgucagc uucuuccccc     1020

aggccgaaac cugcaaaguc caauccaaca gagucuucug cgacaccaug aacucgcuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacauauu caaccccaaa uacgacugca     1140

aaaucaugac cuccaaaacc gacgucagcu caucagucau cacaucccuc ggggccaucg     1200

ucuccugcua cggcaaaacc aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa     1260

cauucuccaa cggcugcgac uacgucucca acaaaggcgu cgacacaguc uccgucggua     1320

acacccucua cugcguaaau aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccu cucgucuucc ccuccgacga auuugacgcc ucaaucagcc     1440

aaguuaacga aaaaaucaac caaucacucg ccuucauccg caaauccgac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuaccacga acaucaugau caccaccaua aucaucguaa     1560

uuaucguaau acuccuaucc cucauagcag uaggccuccu acucuacugc aaagcccguu     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  2760
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2760
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2761
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2761
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2762
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2762
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2763
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2763
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2764
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2764
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2765
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2765
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2766
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2766
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuuaaagcc      120

aaugcaauaa ccacaauacu aacagcagua acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc aacauguuca gcaguaagca aaggauaccu aggagccuua      240

cgcacagguu gguacacuuc cguaauaaca auagaacucu caaauauaaa agaaaacaaa      300

ugcaacggaa ccgaugcaaa aguaaaacua auaaaacaag aauuagacaa auacaaaaac      360

gcaguaacag accuacaauu acuuaugcaa ucaacacccg caacaggauc cggcucagca      420

aucuguucag gaguagcagu augcaaaguu cuccaccuag aaggcgaagu aaacaaaaua      480

aaaucagccc uauuaucuac caauaaagca guaguaucac uaucaaaugg aguaucuguc      540

cuaaccuuca aaguacuuga ccuaaaaaau uacaucgaca aacaauuacu accaauacuu      600

aacaaacaau cauguucaau accaaacauu gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuau uagaaauaac ccgcgaauuu ucaguuaacg caggaguaac aacaccagua      720

uccacauaca uguuaacaaa uucagaacuc uuaucacuua uaaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau gucuaacaau guucaaauag uucgacaaca aucauacucc      840

auaaugugca uaauaaaaga agaaguucua gcauauguug uacaacuccc acucuauggu      900

guuauagaca caccaugcug gaaacuacau acaagccccu uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacccgcaca gacagaggcu gguauugcga uaacgcaggu     1020

ucaguaucau ucuuuccaca agcagaaacu ugcaaagucc aauccaauag agucuucugc     1080

gacacuauga acucacucac acucccaucu gaagucaauu uauguaacgu cgauaucuuc     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguaagcuc aucagucaua     1200

acuucucuag gcgcaaucgu cucauguuac ggcaaaacaa aauguaccgc aucaaacaaa     1260

aaucgaggua uaauaaaaac cuuuucuaac ggcugcgacu acguaucaaa caaaggagua     1320

gauacuguaa gugucggaaa cacauuauac ugcgucaaca aacaagaagg acaaucccua     1380

uauguuaaag gcgaaccuau cauuaauuuc uacgacccac ucgucuuucc auccgacgaa     1440

uuugacgcau caauuuccca aguaaaugaa aaaauaaacc aaucccuugc auucauaaga     1500

aaaucagaug aacuauuaca caacguaaac gcaggcaaau caacaacaaa uauaaugauc     1560

acaacaauaa uaaucguaau aauaguaauc cuacucucac uaauagcagu aggcuuacua     1620

uuauauugca aagccagaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2767
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2767
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuuau ccuaaaagcg      120

aacgccauaa ccacaauccu aacagcaguc accuucuguu ucgccucagg acaaaacauc      180

accgaggaau uuuaccaauc cacauguagc gcugucucaa aaggcuaccu cggcgcccuc      240

cgaaccggcu gguacacauc cguaauaacg aucgaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgccaa agucaaacuu aucaaacaag aacuagacaa auacaaaaac      360

gccgucaccg accuccagcu ccucaugcaa uccaccccag caacaggcuc cggaagcgca      420

aucugcucag gcgucgccgu augcaaagua cuccaccucg aaggagaagu caacaaaauc      480

aaauccgccc uccuauccac aaacaaagca guugucucac ucuccaacgg gguaagcgua      540

cugaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuccu uccaauccuc      600

aacaaacaau caugcucuau ccccaacauc gaaaccguaa ucgaauuuca acaaaaaaac      660

aaccgccuac uugaaaucac acgcgaauuu agcgucaacg caggaguaac aacacccgug      720

uccacauaua ugcucacgaa cagcgaacua cuaucccuga uuaacgacau gcccaucacc      780

aacgaccaaa aaaaacuaau gagcaacaac guacaaaucg uccgccaaca aagcuacucu      840

auaaugugca ucaucaagga agaaguccua gccuacgucg uccaauuacc acucuacggc      900

gucaucgaca cacccugcug gaaacuccau acaucccccc ucugcaccac caacaccaaa      960

gaagggucca acauaugccu cacucgcaca gaccgcggcu gguacugcga caacgcuggc     1020

agcgucagcu ucuuccccca ggccgaaacc ugcaaagucc aauccaacag agucuucugc     1080

gacaccauga acucgcucac ccuccccucc gaggucaacc ucugcaacgu cgacauauuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaaaaccg acgucagcuc aucagucauc     1200

acaucccucg gggccaucgu cuccugcuac ggcaaaacca agugcaccgc cucaaacaaa     1260

aaccgcggca uuaucaaaac auucuccaac ggcugcgacu acgucuccaa caaaggcguc     1320

gacacagucu ccgucgguaa cacccucuac ugcguaaaua aacaagaagg ccaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgacccuc ucgucuuccc cuccgacgaa     1440

uuugacgccu caaucagcca aguuaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaauccgacg aacuccucca caacguuaac gccggcaaau cuaccacgaa caucaugauc     1560

accaccauaa ucaucguaau uaucguaaua cuccuauccc ucauagcagu aggccuccua     1620

cucuacugca aagcccguua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  2768
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2768
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2769
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2769
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2770
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2770
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2771
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2771
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2772
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2772
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2773
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2773
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2774
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2774
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uuaaagccaa ugcaauaacc acaauacuaa cagcaguaac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucaa cauguucagc aguaagcaaa      300

ggauaccuag gagccuuacg cacagguugg uacacuuccg uaauaacaau agaacucuca      360

aauauaaaag aaaacaaaug caacggaacc gaugcaaaag uaaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc aguaacagac cuacaauuac uuaugcaauc aacacccgca      480

acaggauccg gcucagcaau cuguucagga guagcaguau gcaaaguucu ccaccuagaa      540

ggcgaaguaa acaaaauaaa aucagcccua uuaucuacca auaaagcagu aguaucacua      600

ucaaauggag uaucuguccu aaccuucaaa guacuugacc uaaaaaauua caucgacaaa      660

caauuacuac caauacuuaa caaacaauca uguucaauac caaacauuga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuauua gaaauaaccc gcgaauuuuc aguuaacgca      780

ggaguaacaa caccaguauc cacauacaug uuaacaaauu cagaacucuu aucacuuaua      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu cuaacaaugu ucaaauaguu      900

cgacaacaau cauacuccau aaugugcaua auaaaagaag aaguucuagc auauguugua      960

caacucccac ucuauggugu uauagacaca ccaugcugga aacuacauac aagccccuua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa cccgcacaga cagaggcugg     1080

uauugcgaua acgcagguuc aguaucauuc uuuccacaag cagaaacuug caaaguccaa     1140

uccaauagag ucuucugcga cacuaugaac ucacucacac ucccaucuga agucaauuua     1200

uguaacgucg auaucuucaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guaagcucau cagucauaac uucucuaggc gcaaucgucu cauguuacgg caaaacaaaa     1320

uguaccgcau caaacaaaaa ucgagguaua auaaaaaccu uuucuaacgg cugcgacuac     1380

guaucaaaca aaggaguaga uacuguaagu gucggaaaca cauuauacug cgucaacaaa     1440

caagaaggac aaucccuaua uguuaaaggc gaaccuauca uuaauuucua cgacccacuc     1500

gucuuuccau ccgacgaauu ugacgcauca auuucccaag uaaaugaaaa aauaaaccaa     1560

ucccuugcau ucauaagaaa aucagaugaa cuauuacaca acguaaacgc aggcaaauca     1620

acaacaaaua uaaugaucac aacaauaaua aucguaauaa uaguaauccu acucucacua     1680

auagcaguag gcuuacuauu auauugcaaa gccagauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2775
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2775
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuuaucc uaaaagcgaa cgccauaacc acaauccuaa cagcagucac cuucuguuuc      240

gccucaggac aaaacaucac cgaggaauuu uaccaaucca cauguagcgc ugucucaaaa      300

ggcuaccucg gcgcccuccg aaccggcugg uacacauccg uaauaacgau cgaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgccaaag ucaaacuuau caaacaagaa      420

cuagacaaau acaaaaacgc cgucaccgac cuccagcucc ucaugcaauc caccccagca      480

acaggcuccg gaagcgcaau cugcucaggc gucgccguau gcaaaguacu ccaccucgaa      540

ggagaaguca acaaaaucaa auccgcccuc cuauccacaa acaaagcagu ugucucacuc      600

uccaacgggg uaagcguacu gaccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuccuuc caauccucaa caaacaauca ugcucuaucc ccaacaucga aaccguaauc      720

gaauuucaac aaaaaaacaa ccgccuacuu gaaaucacac gcgaauuuag cgucaacgca      780

ggaguaacaa cacccguguc cacauauaug cucacgaaca gcgaacuacu aucccugauu      840

aacgacaugc ccaucaccaa cgaccaaaaa aaacuaauga gcaacaacgu acaaaucguc      900

cgccaacaaa gcuacucuau aaugugcauc aucaaggaag aaguccuagc cuacgucguc      960

caauuaccac ucuacggcgu caucgacaca cccugcugga aacuccauac auccccccuc     1020

ugcaccacca acaccaaaga aggguccaac auaugccuca cucgcacaga ccgcggcugg     1080

uacugcgaca acgcuggcag cgucagcuuc uucccccagg ccgaaaccug caaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucgcucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caaaaccgac     1260

gucagcucau cagucaucac aucccucggg gccaucgucu ccugcuacgg caaaaccaag     1320

ugcaccgccu caaacaaaaa ccgcggcauu aucaaaacau ucuccaacgg cugcgacuac     1380

gucuccaaca aaggcgucga cacagucucc gucgguaaca cccucuacug cguaaauaaa     1440

caagaaggcc aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccucuc     1500

gucuuccccu ccgacgaauu ugacgccuca aucagccaag uuaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa auccgacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

accacgaaca ucaugaucac caccauaauc aucguaauua ucguaauacu ccuaucccuc     1680

auagcaguag gccuccuacu cuacugcaaa gcccguuaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  2776
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2776
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2777
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2777
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2778
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2778
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2779
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2779
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2780
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2780
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2781
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2781
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2782
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2782
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu uaaagccaau gcaauaacca caauacuaac agcaguaaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaaucaac auguucagca      240

guaagcaaag gauaccuagg agccuuacgc acagguuggu acacuuccgu aauaacaaua      300

gaacucucaa auauaaaaga aaacaaaugc aacggaaccg augcaaaagu aaaacuaaua      360

aaacaagaau uagacaaaua caaaaacgca guaacagacc uacaauuacu uaugcaauca      420

acacccgcaa caggauccgg cucagcaauc uguucaggag uagcaguaug caaaguucuc      480

caccuagaag gcgaaguaaa caaaauaaaa ucagcccuau uaucuaccaa uaaagcagua      540

guaucacuau caaauggagu aucuguccua accuucaaag uacuugaccu aaaaaauuac      600

aucgacaaac aauuacuacc aauacuuaac aaacaaucau guucaauacc aaacauugaa      660

acaguaauag aauuucaaca aaaaaauaac agauuauuag aaauaacccg cgaauuuuca      720

guuaacgcag gaguaacaac accaguaucc acauacaugu uaacaaauuc agaacucuua      780

ucacuuauaa acgacaugcc cauaacaaac gaccaaaaaa aacucauguc uaacaauguu      840

caaauaguuc gacaacaauc auacuccaua augugcauaa uaaaagaaga aguucuagca      900

uauguuguac aacucccacu cuaugguguu auagacacac caugcuggaa acuacauaca      960

agccccuuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac ccgcacagac     1020

agaggcuggu auugcgauaa cgcagguuca guaucauucu uuccacaagc agaaacuugc     1080

aaaguccaau ccaauagagu cuucugcgac acuaugaacu cacucacacu cccaucugaa     1140

gucaauuuau guaacgucga uaucuucaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uaagcucauc agucauaacu ucucuaggcg caaucgucuc auguuacggc     1260

aaaacaaaau guaccgcauc aaacaaaaau cgagguauaa uaaaaaccuu uucuaacggc     1320

ugcgacuacg uaucaaacaa aggaguagau acuguaagug ucggaaacac auuauacugc     1380

gucaacaaac aagaaggaca aucccuauau guuaaaggcg aaccuaucau uaauuucuac     1440

gacccacucg ucuuuccauc cgacgaauuu gacgcaucaa uuucccaagu aaaugaaaaa     1500

auaaaccaau cccuugcauu cauaagaaaa ucagaugaac uauuacacaa cguaaacgca     1560

ggcaaaucaa caacaaauau aaugaucaca acaauaauaa ucguaauaau aguaauccua     1620

cucucacuaa uagcaguagg cuuacuauua uauugcaaag ccagauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2783
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2783
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuuauccu aaaagcgaac gccauaacca caauccuaac agcagucacc      180

uucuguuucg ccucaggaca aaacaucacc gaggaauuuu accaauccac auguagcgcu      240

gucucaaaag gcuaccucgg cgcccuccga accggcuggu acacauccgu aauaacgauc      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgccaaagu caaacuuauc      360

aaacaagaac uagacaaaua caaaaacgcc gucaccgacc uccagcuccu caugcaaucc      420

accccagcaa caggcuccgg aagcgcaauc ugcucaggcg ucgccguaug caaaguacuc      480

caccucgaag gagaagucaa caaaaucaaa uccgcccucc uauccacaaa caaagcaguu      540

gucucacucu ccaacggggu aagcguacug accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuccuucc aauccucaac aaacaaucau gcucuauccc caacaucgaa      660

accguaaucg aauuucaaca aaaaaacaac cgccuacuug aaaucacacg cgaauuuagc      720

gucaacgcag gaguaacaac acccgugucc acauauaugc ucacgaacag cgaacuacua      780

ucccugauua acgacaugcc caucaccaac gaccaaaaaa aacuaaugag caacaacgua      840

caaaucgucc gccaacaaag cuacucuaua augugcauca ucaaggaaga aguccuagcc      900

uacgucgucc aauuaccacu cuacggcguc aucgacacac ccugcuggaa acuccauaca      960

uccccccucu gcaccaccaa caccaaagaa ggguccaaca uaugccucac ucgcacagac     1020

cgcggcuggu acugcgacaa cgcuggcagc gucagcuucu ucccccaggc cgaaaccugc     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cgcucacccu ccccuccgag     1140

gucaaccucu gcaacgucga cauauucaac cccaaauacg acugcaaaau caugaccucc     1200

aaaaccgacg ucagcucauc agucaucaca ucccucgggg ccaucgucuc cugcuacggc     1260

aaaaccaagu gcaccgccuc aaacaaaaac cgcggcauua ucaaaacauu cuccaacggc     1320

ugcgacuacg ucuccaacaa aggcgucgac acagucuccg ucgguaacac ccucuacugc     1380

guaaauaaac aagaaggcca aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccucucg ucuuccccuc cgacgaauuu gacgccucaa ucagccaagu uaacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa uccgacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua ccacgaacau caugaucacc accauaauca ucguaauuau cguaauacuc     1620

cuaucccuca uagcaguagg ccuccuacuc uacugcaaag cccguuaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  2784
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2784
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2785
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2785
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2786
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2786
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2787
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2787
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2788
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2788
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2789
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2789
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2790
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2790
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuuaaa gccaaugcaa uaaccacaau acuaacagca      120

guaacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca aucaacaugu      180

ucagcaguaa gcaaaggaua ccuaggagcc uuacgcacag guugguacac uuccguaaua      240

acaauagaac ucucaaauau aaaagaaaac aaaugcaacg gaaccgaugc aaaaguaaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgcaguaa cagaccuaca auuacuuaug      360

caaucaacac ccgcaacagg auccggcuca gcaaucuguu caggaguagc aguaugcaaa      420

guucuccacc uagaaggcga aguaaacaaa auaaaaucag cccuauuauc uaccaauaaa      480

gcaguaguau cacuaucaaa uggaguaucu guccuaaccu ucaaaguacu ugaccuaaaa      540

aauuacaucg acaaacaauu acuaccaaua cuuaacaaac aaucauguuc aauaccaaac      600

auugaaacag uaauagaauu ucaacaaaaa aauaacagau uauuagaaau aacccgcgaa      660

uuuucaguua acgcaggagu aacaacacca guauccacau acauguuaac aaauucagaa      720

cucuuaucac uuauaaacga caugcccaua acaaacgacc aaaaaaaacu caugucuaac      780

aauguucaaa uaguucgaca acaaucauac uccauaaugu gcauaauaaa agaagaaguu      840

cuagcauaug uuguacaacu cccacucuau gguguuauag acacaccaug cuggaaacua      900

cauacaagcc ccuuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacccgc      960

acagacagag gcugguauug cgauaacgca gguucaguau cauucuuucc acaagcagaa     1020

acuugcaaag uccaauccaa uagagucuuc ugcgacacua ugaacucacu cacacuccca     1080

ucugaaguca auuuauguaa cgucgauauc uucaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguaag cucaucaguc auaacuucuc uaggcgcaau cgucucaugu     1200

uacggcaaaa caaaauguac cgcaucaaac aaaaaucgag guauaauaaa aaccuuuucu     1260

aacggcugcg acuacguauc aaacaaagga guagauacug uaagugucgg aaacacauua     1320

uacugcguca acaaacaaga aggacaaucc cuauauguua aaggcgaacc uaucauuaau     1380

uucuacgacc cacucgucuu uccauccgac gaauuugacg caucaauuuc ccaaguaaau     1440

gaaaaaauaa accaaucccu ugcauucaua agaaaaucag augaacuauu acacaacgua     1500

aacgcaggca aaucaacaac aaauauaaug aucacaacaa uaauaaucgu aauaauagua     1560

auccuacucu cacuaauagc aguaggcuua cuauuauauu gcaaagccag auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2791
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2791
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu uauccuaaaa gcgaacgcca uaaccacaau ccuaacagca      120

gucaccuucu guuucgccuc aggacaaaac aucaccgagg aauuuuacca auccacaugu      180

agcgcugucu caaaaggcua ccucggcgcc cuccgaaccg gcugguacac auccguaaua      240

acgaucgaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc caaagucaaa      300

cuuaucaaac aagaacuaga caaauacaaa aacgccguca ccgaccucca gcuccucaug      360

caauccaccc cagcaacagg cuccggaagc gcaaucugcu caggcgucgc cguaugcaaa      420

guacuccacc ucgaaggaga agucaacaaa aucaaauccg cccuccuauc cacaaacaaa      480

gcaguugucu cacucuccaa cgggguaagc guacugaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu ccuuccaauc cucaacaaac aaucaugcuc uauccccaac      600

aucgaaaccg uaaucgaauu ucaacaaaaa aacaaccgcc uacuugaaau cacacgcgaa      660

uuuagcguca acgcaggagu aacaacaccc guguccacau auaugcucac gaacagcgaa      720

cuacuauccc ugauuaacga caugcccauc accaacgacc aaaaaaaacu aaugagcaac      780

aacguacaaa ucguccgcca acaaagcuac ucuauaaugu gcaucaucaa ggaagaaguc      840

cuagccuacg ucguccaauu accacucuac ggcgucaucg acacacccug cuggaaacuc      900

cauacauccc cccucugcac caccaacacc aaagaagggu ccaacauaug ccucacucgc      960

acagaccgcg gcugguacug cgacaacgcu ggcagcguca gcuucuuccc ccaggccgaa     1020

accugcaaag uccaauccaa cagagucuuc ugcgacacca ugaacucgcu cacccucccc     1080

uccgagguca accucugcaa cgucgacaua uucaacccca aauacgacug caaaaucaug     1140

accuccaaaa ccgacgucag cucaucaguc aucacauccc ucggggccau cgucuccugc     1200

uacggcaaaa ccaagugcac cgccucaaac aaaaaccgcg gcauuaucaa aacauucucc     1260

aacggcugcg acuacgucuc caacaaaggc gucgacacag ucuccgucgg uaacacccuc     1320

uacugcguaa auaaacaaga aggccaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cucucgucuu ccccuccgac gaauuugacg ccucaaucag ccaaguuaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaauccg acgaacuccu ccacaacguu     1500

aacgccggca aaucuaccac gaacaucaug aucaccacca uaaucaucgu aauuaucgua     1560

auacuccuau cccucauagc aguaggccuc cuacucuacu gcaaagcccg uuaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  2792
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2792
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2793
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2793
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      660

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1500

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1560

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2794
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2794
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2795
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2795
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      600

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      660

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      720

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      840

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      900

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      960

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua     1020

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc     1080

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg     1140

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1200

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1260

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1320

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1380

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1440

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1500

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1560

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1620

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1680

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1740

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2796
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2796
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2797
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2797
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      600

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      660

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      720

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      840

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      900

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      960

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug     1020

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc     1080

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc     1140

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1200

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1260

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1320

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1380

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1440

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1500

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1560

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1620

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1740

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2798
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2798
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuaa uacuuaaagc caaugcaaua accacaauac uaacagcagu aacauucugc      300

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau caacauguuc agcaguaagc      360

aaaggauacc uaggagccuu acgcacaggu ugguacacuu ccguaauaac aauagaacuc      420

ucaaauauaa aagaaaacaa augcaacgga accgaugcaa aaguaaaacu aauaaaacaa      480

gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau uacuuaugca aucaacaccc      540

gcaacaggau ccggcucagc aaucuguuca ggaguagcag uaugcaaagu ucuccaccua      600

gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua ccaauaaagc aguaguauca      660

cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug accuaaaaaa uuacaucgac      720

aaacaauuac uaccaauacu uaacaaacaa ucauguucaa uaccaaacau ugaaacagua      780

auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa cccgcgaauu uucaguuaac      840

gcaggaguaa caacaccagu auccacauac auguuaacaa auucagaacu cuuaucacuu      900

auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca ugucuaacaa uguucaaaua      960

guucgacaac aaucauacuc cauaaugugc auaauaaaag aagaaguucu agcauauguu     1020

guacaacucc cacucuaugg uguuauagac acaccaugcu ggaaacuaca uacaagcccc     1080

uuaugcacua caaacacaaa agaaggcucu aauauauguc uaacccgcac agacagaggc     1140

ugguauugcg auaacgcagg uucaguauca uucuuuccac aagcagaaac uugcaaaguc     1200

caauccaaua gagucuucug cgacacuaug aacucacuca cacucccauc ugaagucaau     1260

uuauguaacg ucgauaucuu caacccaaaa uacgacugca aaauaaugac cucaaaaaca     1320

gacguaagcu caucagucau aacuucucua ggcgcaaucg ucucauguua cggcaaaaca     1380

aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa ccuuuucuaa cggcugcgac     1440

uacguaucaa acaaaggagu agauacugua agugucggaa acacauuaua cugcgucaac     1500

aaacaagaag gacaaucccu auauguuaaa ggcgaaccua ucauuaauuu cuacgaccca     1560

cucgucuuuc cauccgacga auuugacgca ucaauuuccc aaguaaauga aaaaauaaac     1620

caaucccuug cauucauaag aaaaucagau gaacuauuac acaacguaaa cgcaggcaaa     1680

ucaacaacaa auauaaugau cacaacaaua auaaucguaa uaauaguaau ccuacucuca     1740

cuaauagcag uaggcuuacu auuauauugc aaagccagau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2799
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2799
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuucuua uccuaaaagc gaacgccaua accacaaucc uaacagcagu caccuucugu      300

uucgccucag gacaaaacau caccgaggaa uuuuaccaau ccacauguag cgcugucuca      360

aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau ccguaauaac gaucgaacuc      420

uccaacauaa aagaaaauaa augcaacggc accgacgcca aagucaaacu uaucaaacaa      480

gaacuagaca aauacaaaaa cgccgucacc gaccuccagc uccucaugca auccacccca      540

gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg uaugcaaagu acuccaccuc      600

gaaggagaag ucaacaaaau caaauccgcc cuccuaucca caaacaaagc aguugucuca      660

cucuccaacg ggguaagcgu acugaccuuc aaaguccuag accucaaaaa cuacaucgau      720

aaacaacucc uuccaauccu caacaaacaa ucaugcucua uccccaacau cgaaaccgua      780

aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca cacgcgaauu uagcgucaac      840

gcaggaguaa caacacccgu guccacauau augcucacga acagcgaacu acuaucccug      900

auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa ugagcaacaa cguacaaauc      960

guccgccaac aaagcuacuc uauaaugugc aucaucaagg aagaaguccu agccuacguc     1020

guccaauuac cacucuacgg cgucaucgac acacccugcu ggaaacucca uacauccccc     1080

cucugcacca ccaacaccaa agaagggucc aacauaugcc ucacucgcac agaccgcggc     1140

ugguacugcg acaacgcugg cagcgucagc uucuuccccc aggccgaaac cugcaaaguc     1200

caauccaaca gagucuucug cgacaccaug aacucgcuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacauauu caaccccaaa uacgacugca aaaucaugac cuccaaaacc     1320

gacgucagcu caucagucau cacaucccuc ggggccaucg ucuccugcua cggcaaaacc     1380

aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa cauucuccaa cggcugcgac     1440

uacgucucca acaaaggcgu cgacacaguc uccgucggua acacccucua cugcguaaau     1500

aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccu     1560

cucgucuucc ccuccgacga auuugacgcc ucaaucagcc aaguuaacga aaaaaucaac     1620

caaucacucg ccuucauccg caaauccgac gaacuccucc acaacguuaa cgccggcaaa     1680

ucuaccacga acaucaugau caccaccaua aucaucguaa uuaucguaau acuccuaucc     1740

cucauagcag uaggccuccu acucuacugc aaagcccguu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2800
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2800
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2801
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2801
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2802
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2802
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2803
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2803
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      720

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg      960

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1140

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1440

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2804
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2804
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2805
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2805
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      720

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc      960

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1440

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2806
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2806
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuaa uacuuaaagc caaugcaaua accacaauac uaacagcagu aacauucugc      120

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau caacauguuc agcaguaagc      180

aaaggauacc uaggagccuu acgcacaggu ugguacacuu ccguaauaac aauagaacuc      240

ucaaauauaa aagaaaacaa augcaacgga accgaugcaa aaguaaaacu aauaaaacaa      300

gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau uacuuaugca aucaacaccc      360

gcaacaggau ccggcucagc aaucuguuca ggaguagcag uaugcaaagu ucuccaccua      420

gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua ccaauaaagc aguaguauca      480

cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug accuaaaaaa uuacaucgac      540

aaacaauuac uaccaauacu uaacaaacaa ucauguucaa uaccaaacau ugaaacagua      600

auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa cccgcgaauu uucaguuaac      660

gcaggaguaa caacaccagu auccacauac auguuaacaa auucagaacu cuuaucacuu      720

auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca ugucuaacaa uguucaaaua      780

guucgacaac aaucauacuc cauaaugugc auaauaaaag aagaaguucu agcauauguu      840

guacaacucc cacucuaugg uguuauagac acaccaugcu ggaaacuaca uacaagcccc      900

uuaugcacua caaacacaaa agaaggcucu aauauauguc uaacccgcac agacagaggc      960

ugguauugcg auaacgcagg uucaguauca uucuuuccac aagcagaaac uugcaaaguc     1020

caauccaaua gagucuucug cgacacuaug aacucacuca cacucccauc ugaagucaau     1080

uuauguaacg ucgauaucuu caacccaaaa uacgacugca aaauaaugac cucaaaaaca     1140

gacguaagcu caucagucau aacuucucua ggcgcaaucg ucucauguua cggcaaaaca     1200

aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa ccuuuucuaa cggcugcgac     1260

uacguaucaa acaaaggagu agauacugua agugucggaa acacauuaua cugcgucaac     1320

aaacaagaag gacaaucccu auauguuaaa ggcgaaccua ucauuaauuu cuacgaccca     1380

cucgucuuuc cauccgacga auuugacgca ucaauuuccc aaguaaauga aaaaauaaac     1440

caaucccuug cauucauaag aaaaucagau gaacuauuac acaacguaaa cgcaggcaaa     1500

ucaacaacaa auauaaugau cacaacaaua auaaucguaa uaauaguaau ccuacucuca     1560

cuaauagcag uaggcuuacu auuauauugc aaagccagau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2807
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2807
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuucuua uccuaaaagc gaacgccaua accacaaucc uaacagcagu caccuucugu      120

uucgccucag gacaaaacau caccgaggaa uuuuaccaau ccacauguag cgcugucuca      180

aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau ccguaauaac gaucgaacuc      240

uccaacauaa aagaaaauaa augcaacggc accgacgcca aagucaaacu uaucaaacaa      300

gaacuagaca aauacaaaaa cgccgucacc gaccuccagc uccucaugca auccacccca      360

gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg uaugcaaagu acuccaccuc      420

gaaggagaag ucaacaaaau caaauccgcc cuccuaucca caaacaaagc aguugucuca      480

cucuccaacg ggguaagcgu acugaccuuc aaaguccuag accucaaaaa cuacaucgau      540

aaacaacucc uuccaauccu caacaaacaa ucaugcucua uccccaacau cgaaaccgua      600

aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca cacgcgaauu uagcgucaac      660

gcaggaguaa caacacccgu guccacauau augcucacga acagcgaacu acuaucccug      720

auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa ugagcaacaa cguacaaauc      780

guccgccaac aaagcuacuc uauaaugugc aucaucaagg aagaaguccu agccuacguc      840

guccaauuac cacucuacgg cgucaucgac acacccugcu ggaaacucca uacauccccc      900

cucugcacca ccaacaccaa agaagggucc aacauaugcc ucacucgcac agaccgcggc      960

ugguacugcg acaacgcugg cagcgucagc uucuuccccc aggccgaaac cugcaaaguc     1020

caauccaaca gagucuucug cgacaccaug aacucgcuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacauauu caaccccaaa uacgacugca aaaucaugac cuccaaaacc     1140

gacgucagcu caucagucau cacaucccuc ggggccaucg ucuccugcua cggcaaaacc     1200

aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa cauucuccaa cggcugcgac     1260

uacgucucca acaaaggcgu cgacacaguc uccgucggua acacccucua cugcguaaau     1320

aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccu     1380

cucgucuucc ccuccgacga auuugacgcc ucaaucagcc aaguuaacga aaaaaucaac     1440

caaucacucg ccuucauccg caaauccgac gaacuccucc acaacguuaa cgccggcaaa     1500

ucuaccacga acaucaugau caccaccaua aucaucguaa uuaucguaau acuccuaucc     1560

cucauagcag uaggccuccu acucuacugc aaagcccguu aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  2808
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2808
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2809
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2809
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2810
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2810
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2811
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2811
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2812
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2812
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2813
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2813
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2814
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2814
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuuaaagc caaugcaaua accacaauac      120

uaacagcagu aacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

caacauguuc agcaguaagc aaaggauacc uaggagccuu acgcacaggu ugguacacuu      240

ccguaauaac aauagaacuc ucaaauauaa aagaaaacaa augcaacgga accgaugcaa      300

aaguaaaacu aauaaaacaa gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau      360

uacuuaugca aucaacaccc gcaacaggau ccggcucagc aaucuguuca ggaguagcag      420

uaugcaaagu ucuccaccua gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua      480

ccaauaaagc aguaguauca cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug      540

accuaaaaaa uuacaucgac aaacaauuac uaccaauacu uaacaaacaa ucauguucaa      600

uaccaaacau ugaaacagua auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa      660

cccgcgaauu uucaguuaac gcaggaguaa caacaccagu auccacauac auguuaacaa      720

auucagaacu cuuaucacuu auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa uguucaaaua guucgacaac aaucauacuc cauaaugugc auaauaaaag      840

aagaaguucu agcauauguu guacaacucc cacucuaugg uguuauagac acaccaugcu      900

ggaaacuaca uacaagcccc uuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacccgcac agacagaggc ugguauugcg auaacgcagg uucaguauca uucuuuccac     1020

aagcagaaac uugcaaaguc caauccaaua gagucuucug cgacacuaug aacucacuca     1080

cacucccauc ugaagucaau uuauguaacg ucgauaucuu caacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguaagcu caucagucau aacuucucua ggcgcaaucg     1200

ucucauguua cggcaaaaca aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa     1260

ccuuuucuaa cggcugcgac uacguaucaa acaaaggagu agauacugua agugucggaa     1320

acacauuaua cugcgucaac aaacaagaag gacaaucccu auauguuaaa ggcgaaccua     1380

ucauuaauuu cuacgaccca cucgucuuuc cauccgacga auuugacgca ucaauuuccc     1440

aaguaaauga aaaaauaaac caaucccuug cauucauaag aaaaucagau gaacuauuac     1500

acaacguaaa cgcaggcaaa ucaacaacaa auauaaugau cacaacaaua auaaucguaa     1560

uaauaguaau ccuacucuca cuaauagcag uaggcuuacu auuauauugc aaagccagau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2815
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2815
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuua uccuaaaagc gaacgccaua accacaaucc      120

uaacagcagu caccuucugu uucgccucag gacaaaacau caccgaggaa uuuuaccaau      180

ccacauguag cgcugucuca aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau      240

ccguaauaac gaucgaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcca      300

aagucaaacu uaucaaacaa gaacuagaca aauacaaaaa cgccgucacc gaccuccagc      360

uccucaugca auccacccca gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg      420

uaugcaaagu acuccaccuc gaaggagaag ucaacaaaau caaauccgcc cuccuaucca      480

caaacaaagc aguugucuca cucuccaacg ggguaagcgu acugaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacucc uuccaauccu caacaaacaa ucaugcucua      600

uccccaacau cgaaaccgua aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca      660

cacgcgaauu uagcgucaac gcaggaguaa caacacccgu guccacauau augcucacga      720

acagcgaacu acuaucccug auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa      780

ugagcaacaa cguacaaauc guccgccaac aaagcuacuc uauaaugugc aucaucaagg      840

aagaaguccu agccuacguc guccaauuac cacucuacgg cgucaucgac acacccugcu      900

ggaaacucca uacauccccc cucugcacca ccaacaccaa agaagggucc aacauaugcc      960

ucacucgcac agaccgcggc ugguacugcg acaacgcugg cagcgucagc uucuuccccc     1020

aggccgaaac cugcaaaguc caauccaaca gagucuucug cgacaccaug aacucgcuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacauauu caaccccaaa uacgacugca     1140

aaaucaugac cuccaaaacc gacgucagcu caucagucau cacaucccuc ggggccaucg     1200

ucuccugcua cggcaaaacc aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa     1260

cauucuccaa cggcugcgac uacgucucca acaaaggcgu cgacacaguc uccgucggua     1320

acacccucua cugcguaaau aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccu cucgucuucc ccuccgacga auuugacgcc ucaaucagcc     1440

aaguuaacga aaaaaucaac caaucacucg ccuucauccg caaauccgac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuaccacga acaucaugau caccaccaua aucaucguaa     1560

uuaucguaau acuccuaucc cucauagcag uaggccuccu acucuacugc aaagcccguu     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2816
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2816
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2817
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2817
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2818
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2818
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2819
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2819
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2820
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2820
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2821
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2821
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2822
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2822
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuuaaagc caaugcaaua accacaauac      120

uaacagcagu aacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

caacauguuc agcaguaagc aaaggauacc uaggagccuu acgcacaggu ugguacacuu      240

ccguaauaac aauagaacuc ucaaauauaa aagaaaacaa augcaacgga accgaugcaa      300

aaguaaaacu aauaaaacaa gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau      360

uacuuaugca aucaacaccc gcaacaggau ccggcucagc aaucuguuca ggaguagcag      420

uaugcaaagu ucuccaccua gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua      480

ccaauaaagc aguaguauca cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug      540

accuaaaaaa uuacaucgac aaacaauuac uaccaauacu uaacaaacaa ucauguucaa      600

uaccaaacau ugaaacagua auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa      660

cccgcgaauu uucaguuaac gcaggaguaa caacaccagu auccacauac auguuaacaa      720

auucagaacu cuuaucacuu auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa uguucaaaua guucgacaac aaucauacuc cauaaugugc auaauaaaag      840

aagaaguucu agcauauguu guacaacucc cacucuaugg uguuauagac acaccaugcu      900

ggaaacuaca uacaagcccc uuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacccgcac agacagaggc ugguauugcg auaacgcagg uucaguauca uucuuuccac     1020

aagcagaaac uugcaaaguc caauccaaua gagucuucug cgacacuaug aacucacuca     1080

cacucccauc ugaagucaau uuauguaacg ucgauaucuu caacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguaagcu caucagucau aacuucucua ggcgcaaucg     1200

ucucauguua cggcaaaaca aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa     1260

ccuuuucuaa cggcugcgac uacguaucaa acaaaggagu agauacugua agugucggaa     1320

acacauuaua cugcgucaac aaacaagaag gacaaucccu auauguuaaa ggcgaaccua     1380

ucauuaauuu cuacgaccca cucgucuuuc cauccgacga auuugacgca ucaauuuccc     1440

aaguaaauga aaaaauaaac caaucccuug cauucauaag aaaaucagau gaacuauuac     1500

acaacguaaa cgcaggcaaa ucaacaacaa auauaaugau cacaacaaua auaaucguaa     1560

uaauaguaau ccuacucuca cuaauagcag uaggcuuacu auuauauugc aaagccagau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2823
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2823
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuua uccuaaaagc gaacgccaua accacaaucc      120

uaacagcagu caccuucugu uucgccucag gacaaaacau caccgaggaa uuuuaccaau      180

ccacauguag cgcugucuca aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau      240

ccguaauaac gaucgaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcca      300

aagucaaacu uaucaaacaa gaacuagaca aauacaaaaa cgccgucacc gaccuccagc      360

uccucaugca auccacccca gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg      420

uaugcaaagu acuccaccuc gaaggagaag ucaacaaaau caaauccgcc cuccuaucca      480

caaacaaagc aguugucuca cucuccaacg ggguaagcgu acugaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacucc uuccaauccu caacaaacaa ucaugcucua      600

uccccaacau cgaaaccgua aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca      660

cacgcgaauu uagcgucaac gcaggaguaa caacacccgu guccacauau augcucacga      720

acagcgaacu acuaucccug auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa      780

ugagcaacaa cguacaaauc guccgccaac aaagcuacuc uauaaugugc aucaucaagg      840

aagaaguccu agccuacguc guccaauuac cacucuacgg cgucaucgac acacccugcu      900

ggaaacucca uacauccccc cucugcacca ccaacaccaa agaagggucc aacauaugcc      960

ucacucgcac agaccgcggc ugguacugcg acaacgcugg cagcgucagc uucuuccccc     1020

aggccgaaac cugcaaaguc caauccaaca gagucuucug cgacaccaug aacucgcuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacauauu caaccccaaa uacgacugca     1140

aaaucaugac cuccaaaacc gacgucagcu caucagucau cacaucccuc ggggccaucg     1200

ucuccugcua cggcaaaacc aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa     1260

cauucuccaa cggcugcgac uacgucucca acaaaggcgu cgacacaguc uccgucggua     1320

acacccucua cugcguaaau aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccu cucgucuucc ccuccgacga auuugacgcc ucaaucagcc     1440

aaguuaacga aaaaaucaac caaucacucg ccuucauccg caaauccgac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuaccacga acaucaugau caccaccaua aucaucguaa     1560

uuaucguaau acuccuaucc cucauagcag uaggccuccu acucuacugc aaagcccguu     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  2824
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2824
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2825
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2825
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2826
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2826
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2827
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2827
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2828
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2828
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2829
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2829
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2830
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2830
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu uaaagccaau gcaauaacca caauacuaac agcaguaaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaaucaac auguucagca      240

guaagcaaag gauaccuagg agccuuacgc acagguuggu acacuuccgu aauaacaaua      300

gaacucucaa auauaaaaga aaacaaaugc aacggaaccg augcaaaagu aaaacuaaua      360

aaacaagaau uagacaaaua caaaaacgca guaacagacc uacaauuacu uaugcaauca      420

acacccgcaa caggauccgg cucagcaauc uguucaggag uagcaguaug caaaguucuc      480

caccuagaag gcgaaguaaa caaaauaaaa ucagcccuau uaucuaccaa uaaagcagua      540

guaucacuau caaauggagu aucuguccua accuucaaag uacuugaccu aaaaaauuac      600

aucgacaaac aauuacuacc aauacuuaac aaacaaucau guucaauacc aaacauugaa      660

acaguaauag aauuucaaca aaaaaauaac agauuauuag aaauaacccg cgaauuuuca      720

guuaacgcag gaguaacaac accaguaucc acauacaugu uaacaaauuc agaacucuua      780

ucacuuauaa acgacaugcc cauaacaaac gaccaaaaaa aacucauguc uaacaauguu      840

caaauaguuc gacaacaauc auacuccaua augugcauaa uaaaagaaga aguucuagca      900

uauguuguac aacucccacu cuaugguguu auagacacac caugcuggaa acuacauaca      960

agccccuuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac ccgcacagac     1020

agaggcuggu auugcgauaa cgcagguuca guaucauucu uuccacaagc agaaacuugc     1080

aaaguccaau ccaauagagu cuucugcgac acuaugaacu cacucacacu cccaucugaa     1140

gucaauuuau guaacgucga uaucuucaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uaagcucauc agucauaacu ucucuaggcg caaucgucuc auguuacggc     1260

aaaacaaaau guaccgcauc aaacaaaaau cgagguauaa uaaaaaccuu uucuaacggc     1320

ugcgacuacg uaucaaacaa aggaguagau acuguaagug ucggaaacac auuauacugc     1380

gucaacaaac aagaaggaca aucccuauau guuaaaggcg aaccuaucau uaauuucuac     1440

gacccacucg ucuuuccauc cgacgaauuu gacgcaucaa uuucccaagu aaaugaaaaa     1500

auaaaccaau cccuugcauu cauaagaaaa ucagaugaac uauuacacaa cguaaacgca     1560

ggcaaaucaa caacaaauau aaugaucaca acaauaauaa ucguaauaau aguaauccua     1620

cucucacuaa uagcaguagg cuuacuauua uauugcaaag ccagauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2831
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2831
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuuauccu aaaagcgaac gccauaacca caauccuaac agcagucacc      180

uucuguuucg ccucaggaca aaacaucacc gaggaauuuu accaauccac auguagcgcu      240

gucucaaaag gcuaccucgg cgcccuccga accggcuggu acacauccgu aauaacgauc      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgccaaagu caaacuuauc      360

aaacaagaac uagacaaaua caaaaacgcc gucaccgacc uccagcuccu caugcaaucc      420

accccagcaa caggcuccgg aagcgcaauc ugcucaggcg ucgccguaug caaaguacuc      480

caccucgaag gagaagucaa caaaaucaaa uccgcccucc uauccacaaa caaagcaguu      540

gucucacucu ccaacggggu aagcguacug accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuccuucc aauccucaac aaacaaucau gcucuauccc caacaucgaa      660

accguaaucg aauuucaaca aaaaaacaac cgccuacuug aaaucacacg cgaauuuagc      720

gucaacgcag gaguaacaac acccgugucc acauauaugc ucacgaacag cgaacuacua      780

ucccugauua acgacaugcc caucaccaac gaccaaaaaa aacuaaugag caacaacgua      840

caaaucgucc gccaacaaag cuacucuaua augugcauca ucaaggaaga aguccuagcc      900

uacgucgucc aauuaccacu cuacggcguc aucgacacac ccugcuggaa acuccauaca      960

uccccccucu gcaccaccaa caccaaagaa ggguccaaca uaugccucac ucgcacagac     1020

cgcggcuggu acugcgacaa cgcuggcagc gucagcuucu ucccccaggc cgaaaccugc     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cgcucacccu ccccuccgag     1140

gucaaccucu gcaacgucga cauauucaac cccaaauacg acugcaaaau caugaccucc     1200

aaaaccgacg ucagcucauc agucaucaca ucccucgggg ccaucgucuc cugcuacggc     1260

aaaaccaagu gcaccgccuc aaacaaaaac cgcggcauua ucaaaacauu cuccaacggc     1320

ugcgacuacg ucuccaacaa aggcgucgac acagucuccg ucgguaacac ccucuacugc     1380

guaaauaaac aagaaggcca aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccucucg ucuuccccuc cgacgaauuu gacgccucaa ucagccaagu uaacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa uccgacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua ccacgaacau caugaucacc accauaauca ucguaauuau cguaauacuc     1620

cuaucccuca uagcaguagg ccuccuacuc uacugcaaag cccguuaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  2832
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2832
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2833
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2833
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2834
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2834
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2835
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2835
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2836
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2836
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2837
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2837
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2838
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2838
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuuaaagcc      120

aaugcaauaa ccacaauacu aacagcagua acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc aacauguuca gcaguaagca aaggauaccu aggagccuua      240

cgcacagguu gguacacuuc cguaauaaca auagaacucu caaauauaaa agaaaacaaa      300

ugcaacggaa ccgaugcaaa aguaaaacua auaaaacaag aauuagacaa auacaaaaac      360

gcaguaacag accuacaauu acuuaugcaa ucaacacccg caacaggauc cggcucagca      420

aucuguucag gaguagcagu augcaaaguu cuccaccuag aaggcgaagu aaacaaaaua      480

aaaucagccc uauuaucuac caauaaagca guaguaucac uaucaaaugg aguaucuguc      540

cuaaccuuca aaguacuuga ccuaaaaaau uacaucgaca aacaauuacu accaauacuu      600

aacaaacaau cauguucaau accaaacauu gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuau uagaaauaac ccgcgaauuu ucaguuaacg caggaguaac aacaccagua      720

uccacauaca uguuaacaaa uucagaacuc uuaucacuua uaaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau gucuaacaau guucaaauag uucgacaaca aucauacucc      840

auaaugugca uaauaaaaga agaaguucua gcauauguug uacaacuccc acucuauggu      900

guuauagaca caccaugcug gaaacuacau acaagccccu uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacccgcaca gacagaggcu gguauugcga uaacgcaggu     1020

ucaguaucau ucuuuccaca agcagaaacu ugcaaagucc aauccaauag agucuucugc     1080

gacacuauga acucacucac acucccaucu gaagucaauu uauguaacgu cgauaucuuc     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguaagcuc aucagucaua     1200

acuucucuag gcgcaaucgu cucauguuac ggcaaaacaa aauguaccgc aucaaacaaa     1260

aaucgaggua uaauaaaaac cuuuucuaac ggcugcgacu acguaucaaa caaaggagua     1320

gauacuguaa gugucggaaa cacauuauac ugcgucaaca aacaagaagg acaaucccua     1380

uauguuaaag gcgaaccuau cauuaauuuc uacgacccac ucgucuuucc auccgacgaa     1440

uuugacgcau caauuuccca aguaaaugaa aaaauaaacc aaucccuugc auucauaaga     1500

aaaucagaug aacuauuaca caacguaaac gcaggcaaau caacaacaaa uauaaugauc     1560

acaacaauaa uaaucguaau aauaguaauc cuacucucac uaauagcagu aggcuuacua     1620

uuauauugca aagccagaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2839
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2839
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuuau ccuaaaagcg      120

aacgccauaa ccacaauccu aacagcaguc accuucuguu ucgccucagg acaaaacauc      180

accgaggaau uuuaccaauc cacauguagc gcugucucaa aaggcuaccu cggcgcccuc      240

cgaaccggcu gguacacauc cguaauaacg aucgaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgccaa agucaaacuu aucaaacaag aacuagacaa auacaaaaac      360

gccgucaccg accuccagcu ccucaugcaa uccaccccag caacaggcuc cggaagcgca      420

aucugcucag gcgucgccgu augcaaagua cuccaccucg aaggagaagu caacaaaauc      480

aaauccgccc uccuauccac aaacaaagca guugucucac ucuccaacgg gguaagcgua      540

cugaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuccu uccaauccuc      600

aacaaacaau caugcucuau ccccaacauc gaaaccguaa ucgaauuuca acaaaaaaac      660

aaccgccuac uugaaaucac acgcgaauuu agcgucaacg caggaguaac aacacccgug      720

uccacauaua ugcucacgaa cagcgaacua cuaucccuga uuaacgacau gcccaucacc      780

aacgaccaaa aaaaacuaau gagcaacaac guacaaaucg uccgccaaca aagcuacucu      840

auaaugugca ucaucaagga agaaguccua gccuacgucg uccaauuacc acucuacggc      900

gucaucgaca cacccugcug gaaacuccau acaucccccc ucugcaccac caacaccaaa      960

gaagggucca acauaugccu cacucgcaca gaccgcggcu gguacugcga caacgcuggc     1020

agcgucagcu ucuuccccca ggccgaaacc ugcaaagucc aauccaacag agucuucugc     1080

gacaccauga acucgcucac ccuccccucc gaggucaacc ucugcaacgu cgacauauuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaaaaccg acgucagcuc aucagucauc     1200

acaucccucg gggccaucgu cuccugcuac ggcaaaacca agugcaccgc cucaaacaaa     1260

aaccgcggca uuaucaaaac auucuccaac ggcugcgacu acgucuccaa caaaggcguc     1320

gacacagucu ccgucgguaa cacccucuac ugcguaaaua aacaagaagg ccaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgacccuc ucgucuuccc cuccgacgaa     1440

uuugacgccu caaucagcca aguuaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaauccgacg aacuccucca caacguuaac gccggcaaau cuaccacgaa caucaugauc     1560

accaccauaa ucaucguaau uaucguaaua cuccuauccc ucauagcagu aggccuccua     1620

cucuacugca aagcccguua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  2840
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2840
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2841
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2841
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2842
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2842
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2843
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2843
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2844
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2844
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2845
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2845
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2846
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2846
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu uaaagccaau gcaauaacca caauacuaac agcaguaaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaaucaac auguucagca      240

guaagcaaag gauaccuagg agccuuacgc acagguuggu acacuuccgu aauaacaaua      300

gaacucucaa auauaaaaga aaacaaaugc aacggaaccg augcaaaagu aaaacuaaua      360

aaacaagaau uagacaaaua caaaaacgca guaacagacc uacaauuacu uaugcaauca      420

acacccgcaa caggauccgg cucagcaauc uguucaggag uagcaguaug caaaguucuc      480

caccuagaag gcgaaguaaa caaaauaaaa ucagcccuau uaucuaccaa uaaagcagua      540

guaucacuau caaauggagu aucuguccua accuucaaag uacuugaccu aaaaaauuac      600

aucgacaaac aauuacuacc aauacuuaac aaacaaucau guucaauacc aaacauugaa      660

acaguaauag aauuucaaca aaaaaauaac agauuauuag aaauaacccg cgaauuuuca      720

guuaacgcag gaguaacaac accaguaucc acauacaugu uaacaaauuc agaacucuua      780

ucacuuauaa acgacaugcc cauaacaaac gaccaaaaaa aacucauguc uaacaauguu      840

caaauaguuc gacaacaauc auacuccaua augugcauaa uaaaagaaga aguucuagca      900

uauguuguac aacucccacu cuaugguguu auagacacac caugcuggaa acuacauaca      960

agccccuuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac ccgcacagac     1020

agaggcuggu auugcgauaa cgcagguuca guaucauucu uuccacaagc agaaacuugc     1080

aaaguccaau ccaauagagu cuucugcgac acuaugaacu cacucacacu cccaucugaa     1140

gucaauuuau guaacgucga uaucuucaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uaagcucauc agucauaacu ucucuaggcg caaucgucuc auguuacggc     1260

aaaacaaaau guaccgcauc aaacaaaaau cgagguauaa uaaaaaccuu uucuaacggc     1320

ugcgacuacg uaucaaacaa aggaguagau acuguaagug ucggaaacac auuauacugc     1380

gucaacaaac aagaaggaca aucccuauau guuaaaggcg aaccuaucau uaauuucuac     1440

gacccacucg ucuuuccauc cgacgaauuu gacgcaucaa uuucccaagu aaaugaaaaa     1500

auaaaccaau cccuugcauu cauaagaaaa ucagaugaac uauuacacaa cguaaacgca     1560

ggcaaaucaa caacaaauau aaugaucaca acaauaauaa ucguaauaau aguaauccua     1620

cucucacuaa uagcaguagg cuuacuauua uauugcaaag ccagauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2847
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2847
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuuauccu aaaagcgaac gccauaacca caauccuaac agcagucacc      180

uucuguuucg ccucaggaca aaacaucacc gaggaauuuu accaauccac auguagcgcu      240

gucucaaaag gcuaccucgg cgcccuccga accggcuggu acacauccgu aauaacgauc      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgccaaagu caaacuuauc      360

aaacaagaac uagacaaaua caaaaacgcc gucaccgacc uccagcuccu caugcaaucc      420

accccagcaa caggcuccgg aagcgcaauc ugcucaggcg ucgccguaug caaaguacuc      480

caccucgaag gagaagucaa caaaaucaaa uccgcccucc uauccacaaa caaagcaguu      540

gucucacucu ccaacggggu aagcguacug accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuccuucc aauccucaac aaacaaucau gcucuauccc caacaucgaa      660

accguaaucg aauuucaaca aaaaaacaac cgccuacuug aaaucacacg cgaauuuagc      720

gucaacgcag gaguaacaac acccgugucc acauauaugc ucacgaacag cgaacuacua      780

ucccugauua acgacaugcc caucaccaac gaccaaaaaa aacuaaugag caacaacgua      840

caaaucgucc gccaacaaag cuacucuaua augugcauca ucaaggaaga aguccuagcc      900

uacgucgucc aauuaccacu cuacggcguc aucgacacac ccugcuggaa acuccauaca      960

uccccccucu gcaccaccaa caccaaagaa ggguccaaca uaugccucac ucgcacagac     1020

cgcggcuggu acugcgacaa cgcuggcagc gucagcuucu ucccccaggc cgaaaccugc     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cgcucacccu ccccuccgag     1140

gucaaccucu gcaacgucga cauauucaac cccaaauacg acugcaaaau caugaccucc     1200

aaaaccgacg ucagcucauc agucaucaca ucccucgggg ccaucgucuc cugcuacggc     1260

aaaaccaagu gcaccgccuc aaacaaaaac cgcggcauua ucaaaacauu cuccaacggc     1320

ugcgacuacg ucuccaacaa aggcgucgac acagucuccg ucgguaacac ccucuacugc     1380

guaaauaaac aagaaggcca aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccucucg ucuuccccuc cgacgaauuu gacgccucaa ucagccaagu uaacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa uccgacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua ccacgaacau caugaucacc accauaauca ucguaauuau cguaauacuc     1620

cuaucccuca uagcaguagg ccuccuacuc uacugcaaag cccguuaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  2848
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2848
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2849
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2849
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2850
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2850
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2851
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2851
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2852
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2852
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2853
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2853
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2854
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2854
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuuaaagcc      120

aaugcaauaa ccacaauacu aacagcagua acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc aacauguuca gcaguaagca aaggauaccu aggagccuua      240

cgcacagguu gguacacuuc cguaauaaca auagaacucu caaauauaaa agaaaacaaa      300

ugcaacggaa ccgaugcaaa aguaaaacua auaaaacaag aauuagacaa auacaaaaac      360

gcaguaacag accuacaauu acuuaugcaa ucaacacccg caacaggauc cggcucagca      420

aucuguucag gaguagcagu augcaaaguu cuccaccuag aaggcgaagu aaacaaaaua      480

aaaucagccc uauuaucuac caauaaagca guaguaucac uaucaaaugg aguaucuguc      540

cuaaccuuca aaguacuuga ccuaaaaaau uacaucgaca aacaauuacu accaauacuu      600

aacaaacaau cauguucaau accaaacauu gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuau uagaaauaac ccgcgaauuu ucaguuaacg caggaguaac aacaccagua      720

uccacauaca uguuaacaaa uucagaacuc uuaucacuua uaaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau gucuaacaau guucaaauag uucgacaaca aucauacucc      840

auaaugugca uaauaaaaga agaaguucua gcauauguug uacaacuccc acucuauggu      900

guuauagaca caccaugcug gaaacuacau acaagccccu uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacccgcaca gacagaggcu gguauugcga uaacgcaggu     1020

ucaguaucau ucuuuccaca agcagaaacu ugcaaagucc aauccaauag agucuucugc     1080

gacacuauga acucacucac acucccaucu gaagucaauu uauguaacgu cgauaucuuc     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguaagcuc aucagucaua     1200

acuucucuag gcgcaaucgu cucauguuac ggcaaaacaa aauguaccgc aucaaacaaa     1260

aaucgaggua uaauaaaaac cuuuucuaac ggcugcgacu acguaucaaa caaaggagua     1320

gauacuguaa gugucggaaa cacauuauac ugcgucaaca aacaagaagg acaaucccua     1380

uauguuaaag gcgaaccuau cauuaauuuc uacgacccac ucgucuuucc auccgacgaa     1440

uuugacgcau caauuuccca aguaaaugaa aaaauaaacc aaucccuugc auucauaaga     1500

aaaucagaug aacuauuaca caacguaaac gcaggcaaau caacaacaaa uauaaugauc     1560

acaacaauaa uaaucguaau aauaguaauc cuacucucac uaauagcagu aggcuuacua     1620

uuauauugca aagccagaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2855
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2855
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuuau ccuaaaagcg      120

aacgccauaa ccacaauccu aacagcaguc accuucuguu ucgccucagg acaaaacauc      180

accgaggaau uuuaccaauc cacauguagc gcugucucaa aaggcuaccu cggcgcccuc      240

cgaaccggcu gguacacauc cguaauaacg aucgaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgccaa agucaaacuu aucaaacaag aacuagacaa auacaaaaac      360

gccgucaccg accuccagcu ccucaugcaa uccaccccag caacaggcuc cggaagcgca      420

aucugcucag gcgucgccgu augcaaagua cuccaccucg aaggagaagu caacaaaauc      480

aaauccgccc uccuauccac aaacaaagca guugucucac ucuccaacgg gguaagcgua      540

cugaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuccu uccaauccuc      600

aacaaacaau caugcucuau ccccaacauc gaaaccguaa ucgaauuuca acaaaaaaac      660

aaccgccuac uugaaaucac acgcgaauuu agcgucaacg caggaguaac aacacccgug      720

uccacauaua ugcucacgaa cagcgaacua cuaucccuga uuaacgacau gcccaucacc      780

aacgaccaaa aaaaacuaau gagcaacaac guacaaaucg uccgccaaca aagcuacucu      840

auaaugugca ucaucaagga agaaguccua gccuacgucg uccaauuacc acucuacggc      900

gucaucgaca cacccugcug gaaacuccau acaucccccc ucugcaccac caacaccaaa      960

gaagggucca acauaugccu cacucgcaca gaccgcggcu gguacugcga caacgcuggc     1020

agcgucagcu ucuuccccca ggccgaaacc ugcaaagucc aauccaacag agucuucugc     1080

gacaccauga acucgcucac ccuccccucc gaggucaacc ucugcaacgu cgacauauuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaaaaccg acgucagcuc aucagucauc     1200

acaucccucg gggccaucgu cuccugcuac ggcaaaacca agugcaccgc cucaaacaaa     1260

aaccgcggca uuaucaaaac auucuccaac ggcugcgacu acgucuccaa caaaggcguc     1320

gacacagucu ccgucgguaa cacccucuac ugcguaaaua aacaagaagg ccaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgacccuc ucgucuuccc cuccgacgaa     1440

uuugacgccu caaucagcca aguuaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaauccgacg aacuccucca caacguuaac gccggcaaau cuaccacgaa caucaugauc     1560

accaccauaa ucaucguaau uaucguaaua cuccuauccc ucauagcagu aggccuccua     1620

cucuacugca aagcccguua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  2856
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2856
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2857
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2857
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2858
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2858
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2859
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2859
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2860
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2860
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2861
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2861
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2862
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2862
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuuaaagcc      120

aaugcaauaa ccacaauacu aacagcagua acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc aacauguuca gcaguaagca aaggauaccu aggagccuua      240

cgcacagguu gguacacuuc cguaauaaca auagaacucu caaauauaaa agaaaacaaa      300

ugcaacggaa ccgaugcaaa aguaaaacua auaaaacaag aauuagacaa auacaaaaac      360

gcaguaacag accuacaauu acuuaugcaa ucaacacccg caacaggauc cggcucagca      420

aucuguucag gaguagcagu augcaaaguu cuccaccuag aaggcgaagu aaacaaaaua      480

aaaucagccc uauuaucuac caauaaagca guaguaucac uaucaaaugg aguaucuguc      540

cuaaccuuca aaguacuuga ccuaaaaaau uacaucgaca aacaauuacu accaauacuu      600

aacaaacaau cauguucaau accaaacauu gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuau uagaaauaac ccgcgaauuu ucaguuaacg caggaguaac aacaccagua      720

uccacauaca uguuaacaaa uucagaacuc uuaucacuua uaaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau gucuaacaau guucaaauag uucgacaaca aucauacucc      840

auaaugugca uaauaaaaga agaaguucua gcauauguug uacaacuccc acucuauggu      900

guuauagaca caccaugcug gaaacuacau acaagccccu uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacccgcaca gacagaggcu gguauugcga uaacgcaggu     1020

ucaguaucau ucuuuccaca agcagaaacu ugcaaagucc aauccaauag agucuucugc     1080

gacacuauga acucacucac acucccaucu gaagucaauu uauguaacgu cgauaucuuc     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguaagcuc aucagucaua     1200

acuucucuag gcgcaaucgu cucauguuac ggcaaaacaa aauguaccgc aucaaacaaa     1260

aaucgaggua uaauaaaaac cuuuucuaac ggcugcgacu acguaucaaa caaaggagua     1320

gauacuguaa gugucggaaa cacauuauac ugcgucaaca aacaagaagg acaaucccua     1380

uauguuaaag gcgaaccuau cauuaauuuc uacgacccac ucgucuuucc auccgacgaa     1440

uuugacgcau caauuuccca aguaaaugaa aaaauaaacc aaucccuugc auucauaaga     1500

aaaucagaug aacuauuaca caacguaaac gcaggcaaau caacaacaaa uauaaugauc     1560

acaacaauaa uaaucguaau aauaguaauc cuacucucac uaauagcagu aggcuuacua     1620

uuauauugca aagccagaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2863
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2863
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuuau ccuaaaagcg      120

aacgccauaa ccacaauccu aacagcaguc accuucuguu ucgccucagg acaaaacauc      180

accgaggaau uuuaccaauc cacauguagc gcugucucaa aaggcuaccu cggcgcccuc      240

cgaaccggcu gguacacauc cguaauaacg aucgaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgccaa agucaaacuu aucaaacaag aacuagacaa auacaaaaac      360

gccgucaccg accuccagcu ccucaugcaa uccaccccag caacaggcuc cggaagcgca      420

aucugcucag gcgucgccgu augcaaagua cuccaccucg aaggagaagu caacaaaauc      480

aaauccgccc uccuauccac aaacaaagca guugucucac ucuccaacgg gguaagcgua      540

cugaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuccu uccaauccuc      600

aacaaacaau caugcucuau ccccaacauc gaaaccguaa ucgaauuuca acaaaaaaac      660

aaccgccuac uugaaaucac acgcgaauuu agcgucaacg caggaguaac aacacccgug      720

uccacauaua ugcucacgaa cagcgaacua cuaucccuga uuaacgacau gcccaucacc      780

aacgaccaaa aaaaacuaau gagcaacaac guacaaaucg uccgccaaca aagcuacucu      840

auaaugugca ucaucaagga agaaguccua gccuacgucg uccaauuacc acucuacggc      900

gucaucgaca cacccugcug gaaacuccau acaucccccc ucugcaccac caacaccaaa      960

gaagggucca acauaugccu cacucgcaca gaccgcggcu gguacugcga caacgcuggc     1020

agcgucagcu ucuuccccca ggccgaaacc ugcaaagucc aauccaacag agucuucugc     1080

gacaccauga acucgcucac ccuccccucc gaggucaacc ucugcaacgu cgacauauuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaaaaccg acgucagcuc aucagucauc     1200

acaucccucg gggccaucgu cuccugcuac ggcaaaacca agugcaccgc cucaaacaaa     1260

aaccgcggca uuaucaaaac auucuccaac ggcugcgacu acgucuccaa caaaggcguc     1320

gacacagucu ccgucgguaa cacccucuac ugcguaaaua aacaagaagg ccaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgacccuc ucgucuuccc cuccgacgaa     1440

uuugacgccu caaucagcca aguuaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaauccgacg aacuccucca caacguuaac gccggcaaau cuaccacgaa caucaugauc     1560

accaccauaa ucaucguaau uaucguaaua cuccuauccc ucauagcagu aggccuccua     1620

cucuacugca aagcccguua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  2864
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2864
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2865
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2865
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2866
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2866
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2867
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2867
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2868
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2868
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2869
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2869
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2870
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2870
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuuaa agccaaugca      120

auaaccacaa uacuaacagc aguaacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aaucaacaug uucagcagua agcaaaggau accuaggagc cuuacgcaca      240

gguugguaca cuuccguaau aacaauagaa cucucaaaua uaaaagaaaa caaaugcaac      300

ggaaccgaug caaaaguaaa acuaauaaaa caagaauuag acaaauacaa aaacgcagua      360

acagaccuac aauuacuuau gcaaucaaca cccgcaacag gauccggcuc agcaaucugu      420

ucaggaguag caguaugcaa aguucuccac cuagaaggcg aaguaaacaa aauaaaauca      480

gcccuauuau cuaccaauaa agcaguagua ucacuaucaa auggaguauc uguccuaacc      540

uucaaaguac uugaccuaaa aaauuacauc gacaaacaau uacuaccaau acuuaacaaa      600

caaucauguu caauaccaaa cauugaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuauuagaaa uaacccgcga auuuucaguu aacgcaggag uaacaacacc aguauccaca      720

uacauguuaa caaauucaga acucuuauca cuuauaaacg acaugcccau aacaaacgac      780

caaaaaaaac ucaugucuaa caauguucaa auaguucgac aacaaucaua cuccauaaug      840

ugcauaauaa aagaagaagu ucuagcauau guuguacaac ucccacucua ugguguuaua      900

gacacaccau gcuggaaacu acauacaagc cccuuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacccg cacagacaga ggcugguauu gcgauaacgc agguucagua     1020

ucauucuuuc cacaagcaga aacuugcaaa guccaaucca auagagucuu cugcgacacu     1080

augaacucac ucacacuccc aucugaaguc aauuuaugua acgucgauau cuucaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguaa gcucaucagu cauaacuucu     1200

cuaggcgcaa ucgucucaug uuacggcaaa acaaaaugua ccgcaucaaa caaaaaucga     1260

gguauaauaa aaaccuuuuc uaacggcugc gacuacguau caaacaaagg aguagauacu     1320

guaagugucg gaaacacauu auacugcguc aacaaacaag aaggacaauc ccuauauguu     1380

aaaggcgaac cuaucauuaa uuucuacgac ccacucgucu uuccauccga cgaauuugac     1440

gcaucaauuu cccaaguaaa ugaaaaaaua aaccaauccc uugcauucau aagaaaauca     1500

gaugaacuau uacacaacgu aaacgcaggc aaaucaacaa caaauauaau gaucacaaca     1560

auaauaaucg uaauaauagu aauccuacuc ucacuaauag caguaggcuu acuauuauau     1620

ugcaaagcca gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2871
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2871
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uuauccuaaa agcgaacgcc      120

auaaccacaa uccuaacagc agucaccuuc uguuucgccu caggacaaaa caucaccgag      180

gaauuuuacc aauccacaug uagcgcuguc ucaaaaggcu accucggcgc ccuccgaacc      240

ggcugguaca cauccguaau aacgaucgaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg ccaaagucaa acuuaucaaa caagaacuag acaaauacaa aaacgccguc      360

accgaccucc agcuccucau gcaauccacc ccagcaacag gcuccggaag cgcaaucugc      420

ucaggcgucg ccguaugcaa aguacuccac cucgaaggag aagucaacaa aaucaaaucc      480

gcccuccuau ccacaaacaa agcaguuguc ucacucucca acgggguaag cguacugacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uccuuccaau ccucaacaaa      600

caaucaugcu cuauccccaa caucgaaacc guaaucgaau uucaacaaaa aaacaaccgc      660

cuacuugaaa ucacacgcga auuuagcguc aacgcaggag uaacaacacc cguguccaca      720

uauaugcuca cgaacagcga acuacuaucc cugauuaacg acaugcccau caccaacgac      780

caaaaaaaac uaaugagcaa caacguacaa aucguccgcc aacaaagcua cucuauaaug      840

ugcaucauca aggaagaagu ccuagccuac gucguccaau uaccacucua cggcgucauc      900

gacacacccu gcuggaaacu ccauacaucc ccccucugca ccaccaacac caaagaaggg      960

uccaacauau gccucacucg cacagaccgc ggcugguacu gcgacaacgc uggcagcguc     1020

agcuucuucc cccaggccga aaccugcaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucgc ucacccuccc cuccgagguc aaccucugca acgucgacau auucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaaa accgacguca gcucaucagu caucacaucc     1200

cucggggcca ucgucuccug cuacggcaaa accaagugca ccgccucaaa caaaaaccgc     1260

ggcauuauca aaacauucuc caacggcugc gacuacgucu ccaacaaagg cgucgacaca     1320

gucuccgucg guaacacccu cuacugcgua aauaaacaag aaggccaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccucucgucu uccccuccga cgaauuugac     1440

gccucaauca gccaaguuaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaucc     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacca cgaacaucau gaucaccacc     1560

auaaucaucg uaauuaucgu aauacuccua ucccucauag caguaggccu ccuacucuac     1620

ugcaaagccc guuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  2872
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2872
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2873
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2873
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2874
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2874
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2875
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2875
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2876
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2876
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2877
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2877
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2878
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2878
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuuaaa      120

gccaaugcaa uaaccacaau acuaacagca guaacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca aucaacaugu ucagcaguaa gcaaaggaua ccuaggagcc      240

uuacgcacag guugguacac uuccguaaua acaauagaac ucucaaauau aaaagaaaac      300

aaaugcaacg gaaccgaugc aaaaguaaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgcaguaa cagaccuaca auuacuuaug caaucaacac ccgcaacagg auccggcuca      420

gcaaucuguu caggaguagc aguaugcaaa guucuccacc uagaaggcga aguaaacaaa      480

auaaaaucag cccuauuauc uaccaauaaa gcaguaguau cacuaucaaa uggaguaucu      540

guccuaaccu ucaaaguacu ugaccuaaaa aauuacaucg acaaacaauu acuaccaaua      600

cuuaacaaac aaucauguuc aauaccaaac auugaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uauuagaaau aacccgcgaa uuuucaguua acgcaggagu aacaacacca      720

guauccacau acauguuaac aaauucagaa cucuuaucac uuauaaacga caugcccaua      780

acaaacgacc aaaaaaaacu caugucuaac aauguucaaa uaguucgaca acaaucauac      840

uccauaaugu gcauaauaaa agaagaaguu cuagcauaug uuguacaacu cccacucuau      900

gguguuauag acacaccaug cuggaaacua cauacaagcc ccuuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacccgc acagacagag gcugguauug cgauaacgca     1020

gguucaguau cauucuuucc acaagcagaa acuugcaaag uccaauccaa uagagucuuc     1080

ugcgacacua ugaacucacu cacacuccca ucugaaguca auuuauguaa cgucgauauc     1140

uucaacccaa aauacgacug caaaauaaug accucaaaaa cagacguaag cucaucaguc     1200

auaacuucuc uaggcgcaau cgucucaugu uacggcaaaa caaaauguac cgcaucaaac     1260

aaaaaucgag guauaauaaa aaccuuuucu aacggcugcg acuacguauc aaacaaagga     1320

guagauacug uaagugucgg aaacacauua uacugcguca acaaacaaga aggacaaucc     1380

cuauauguua aaggcgaacc uaucauuaau uucuacgacc cacucgucuu uccauccgac     1440

gaauuugacg caucaauuuc ccaaguaaau gaaaaaauaa accaaucccu ugcauucaua     1500

agaaaaucag augaacuauu acacaacgua aacgcaggca aaucaacaac aaauauaaug     1560

aucacaacaa uaauaaucgu aauaauagua auccuacucu cacuaauagc aguaggcuua     1620

cuauuauauu gcaaagccag auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2879
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2879
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu uauccuaaaa      120

gcgaacgcca uaaccacaau ccuaacagca gucaccuucu guuucgccuc aggacaaaac      180

aucaccgagg aauuuuacca auccacaugu agcgcugucu caaaaggcua ccucggcgcc      240

cuccgaaccg gcugguacac auccguaaua acgaucgaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc caaagucaaa cuuaucaaac aagaacuaga caaauacaaa      360

aacgccguca ccgaccucca gcuccucaug caauccaccc cagcaacagg cuccggaagc      420

gcaaucugcu caggcgucgc cguaugcaaa guacuccacc ucgaaggaga agucaacaaa      480

aucaaauccg cccuccuauc cacaaacaaa gcaguugucu cacucuccaa cgggguaagc      540

guacugaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu ccuuccaauc      600

cucaacaaac aaucaugcuc uauccccaac aucgaaaccg uaaucgaauu ucaacaaaaa      660

aacaaccgcc uacuugaaau cacacgcgaa uuuagcguca acgcaggagu aacaacaccc      720

guguccacau auaugcucac gaacagcgaa cuacuauccc ugauuaacga caugcccauc      780

accaacgacc aaaaaaaacu aaugagcaac aacguacaaa ucguccgcca acaaagcuac      840

ucuauaaugu gcaucaucaa ggaagaaguc cuagccuacg ucguccaauu accacucuac      900

ggcgucaucg acacacccug cuggaaacuc cauacauccc cccucugcac caccaacacc      960

aaagaagggu ccaacauaug ccucacucgc acagaccgcg gcugguacug cgacaacgcu     1020

ggcagcguca gcuucuuccc ccaggccgaa accugcaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucgcu cacccucccc uccgagguca accucugcaa cgucgacaua     1140

uucaacccca aauacgacug caaaaucaug accuccaaaa ccgacgucag cucaucaguc     1200

aucacauccc ucggggccau cgucuccugc uacggcaaaa ccaagugcac cgccucaaac     1260

aaaaaccgcg gcauuaucaa aacauucucc aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag ucuccgucgg uaacacccuc uacugcguaa auaaacaaga aggccaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cucucgucuu ccccuccgac     1440

gaauuugacg ccucaaucag ccaaguuaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaauccg acgaacuccu ccacaacguu aacgccggca aaucuaccac gaacaucaug     1560

aucaccacca uaaucaucgu aauuaucgua auacuccuau cccucauagc aguaggccuc     1620

cuacucuacu gcaaagcccg uuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  2880
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2880
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2881
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2881
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2882
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2882
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2883
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2883
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2884
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2884
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2885
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2885
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2886
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2886
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuuaa agccaaugca      120

auaaccacaa uacuaacagc aguaacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aaucaacaug uucagcagua agcaaaggau accuaggagc cuuacgcaca      240

gguugguaca cuuccguaau aacaauagaa cucucaaaua uaaaagaaaa caaaugcaac      300

ggaaccgaug caaaaguaaa acuaauaaaa caagaauuag acaaauacaa aaacgcagua      360

acagaccuac aauuacuuau gcaaucaaca cccgcaacag gauccggcuc agcaaucugu      420

ucaggaguag caguaugcaa aguucuccac cuagaaggcg aaguaaacaa aauaaaauca      480

gcccuauuau cuaccaauaa agcaguagua ucacuaucaa auggaguauc uguccuaacc      540

uucaaaguac uugaccuaaa aaauuacauc gacaaacaau uacuaccaau acuuaacaaa      600

caaucauguu caauaccaaa cauugaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuauuagaaa uaacccgcga auuuucaguu aacgcaggag uaacaacacc aguauccaca      720

uacauguuaa caaauucaga acucuuauca cuuauaaacg acaugcccau aacaaacgac      780

caaaaaaaac ucaugucuaa caauguucaa auaguucgac aacaaucaua cuccauaaug      840

ugcauaauaa aagaagaagu ucuagcauau guuguacaac ucccacucua ugguguuaua      900

gacacaccau gcuggaaacu acauacaagc cccuuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacccg cacagacaga ggcugguauu gcgauaacgc agguucagua     1020

ucauucuuuc cacaagcaga aacuugcaaa guccaaucca auagagucuu cugcgacacu     1080

augaacucac ucacacuccc aucugaaguc aauuuaugua acgucgauau cuucaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguaa gcucaucagu cauaacuucu     1200

cuaggcgcaa ucgucucaug uuacggcaaa acaaaaugua ccgcaucaaa caaaaaucga     1260

gguauaauaa aaaccuuuuc uaacggcugc gacuacguau caaacaaagg aguagauacu     1320

guaagugucg gaaacacauu auacugcguc aacaaacaag aaggacaauc ccuauauguu     1380

aaaggcgaac cuaucauuaa uuucuacgac ccacucgucu uuccauccga cgaauuugac     1440

gcaucaauuu cccaaguaaa ugaaaaaaua aaccaauccc uugcauucau aagaaaauca     1500

gaugaacuau uacacaacgu aaacgcaggc aaaucaacaa caaauauaau gaucacaaca     1560

auaauaaucg uaauaauagu aauccuacuc ucacuaauag caguaggcuu acuauuauau     1620

ugcaaagcca gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2887
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2887
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uuauccuaaa agcgaacgcc      120

auaaccacaa uccuaacagc agucaccuuc uguuucgccu caggacaaaa caucaccgag      180

gaauuuuacc aauccacaug uagcgcuguc ucaaaaggcu accucggcgc ccuccgaacc      240

ggcugguaca cauccguaau aacgaucgaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg ccaaagucaa acuuaucaaa caagaacuag acaaauacaa aaacgccguc      360

accgaccucc agcuccucau gcaauccacc ccagcaacag gcuccggaag cgcaaucugc      420

ucaggcgucg ccguaugcaa aguacuccac cucgaaggag aagucaacaa aaucaaaucc      480

gcccuccuau ccacaaacaa agcaguuguc ucacucucca acgggguaag cguacugacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uccuuccaau ccucaacaaa      600

caaucaugcu cuauccccaa caucgaaacc guaaucgaau uucaacaaaa aaacaaccgc      660

cuacuugaaa ucacacgcga auuuagcguc aacgcaggag uaacaacacc cguguccaca      720

uauaugcuca cgaacagcga acuacuaucc cugauuaacg acaugcccau caccaacgac      780

caaaaaaaac uaaugagcaa caacguacaa aucguccgcc aacaaagcua cucuauaaug      840

ugcaucauca aggaagaagu ccuagccuac gucguccaau uaccacucua cggcgucauc      900

gacacacccu gcuggaaacu ccauacaucc ccccucugca ccaccaacac caaagaaggg      960

uccaacauau gccucacucg cacagaccgc ggcugguacu gcgacaacgc uggcagcguc     1020

agcuucuucc cccaggccga aaccugcaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucgc ucacccuccc cuccgagguc aaccucugca acgucgacau auucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaaa accgacguca gcucaucagu caucacaucc     1200

cucggggcca ucgucuccug cuacggcaaa accaagugca ccgccucaaa caaaaaccgc     1260

ggcauuauca aaacauucuc caacggcugc gacuacgucu ccaacaaagg cgucgacaca     1320

gucuccgucg guaacacccu cuacugcgua aauaaacaag aaggccaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccucucgucu uccccuccga cgaauuugac     1440

gccucaauca gccaaguuaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaucc     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacca cgaacaucau gaucaccacc     1560

auaaucaucg uaauuaucgu aauacuccua ucccucauag caguaggccu ccuacucuac     1620

ugcaaagccc guuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  2888
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2888
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2889
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2889
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2890
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2890
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2891
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2891
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2892
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2892
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2893
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2893
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2894
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2894
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uuaaagccaa ugcaauaacc acaauacuaa cagcaguaac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucaa cauguucagc aguaagcaaa      300

ggauaccuag gagccuuacg cacagguugg uacacuuccg uaauaacaau agaacucuca      360

aauauaaaag aaaacaaaug caacggaacc gaugcaaaag uaaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc aguaacagac cuacaauuac uuaugcaauc aacacccgca      480

acaggauccg gcucagcaau cuguucagga guagcaguau gcaaaguucu ccaccuagaa      540

ggcgaaguaa acaaaauaaa aucagcccua uuaucuacca auaaagcagu aguaucacua      600

ucaaauggag uaucuguccu aaccuucaaa guacuugacc uaaaaaauua caucgacaaa      660

caauuacuac caauacuuaa caaacaauca uguucaauac caaacauuga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuauua gaaauaaccc gcgaauuuuc aguuaacgca      780

ggaguaacaa caccaguauc cacauacaug uuaacaaauu cagaacucuu aucacuuaua      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu cuaacaaugu ucaaauaguu      900

cgacaacaau cauacuccau aaugugcaua auaaaagaag aaguucuagc auauguugua      960

caacucccac ucuauggugu uauagacaca ccaugcugga aacuacauac aagccccuua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa cccgcacaga cagaggcugg     1080

uauugcgaua acgcagguuc aguaucauuc uuuccacaag cagaaacuug caaaguccaa     1140

uccaauagag ucuucugcga cacuaugaac ucacucacac ucccaucuga agucaauuua     1200

uguaacgucg auaucuucaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guaagcucau cagucauaac uucucuaggc gcaaucgucu cauguuacgg caaaacaaaa     1320

uguaccgcau caaacaaaaa ucgagguaua auaaaaaccu uuucuaacgg cugcgacuac     1380

guaucaaaca aaggaguaga uacuguaagu gucggaaaca cauuauacug cgucaacaaa     1440

caagaaggac aaucccuaua uguuaaaggc gaaccuauca uuaauuucua cgacccacuc     1500

gucuuuccau ccgacgaauu ugacgcauca auuucccaag uaaaugaaaa aauaaaccaa     1560

ucccuugcau ucauaagaaa aucagaugaa cuauuacaca acguaaacgc aggcaaauca     1620

acaacaaaua uaaugaucac aacaauaaua aucguaauaa uaguaauccu acucucacua     1680

auagcaguag gcuuacuauu auauugcaaa gccagauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2895
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2895
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuuaucc uaaaagcgaa cgccauaacc acaauccuaa cagcagucac cuucuguuuc      240

gccucaggac aaaacaucac cgaggaauuu uaccaaucca cauguagcgc ugucucaaaa      300

ggcuaccucg gcgcccuccg aaccggcugg uacacauccg uaauaacgau cgaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgccaaag ucaaacuuau caaacaagaa      420

cuagacaaau acaaaaacgc cgucaccgac cuccagcucc ucaugcaauc caccccagca      480

acaggcuccg gaagcgcaau cugcucaggc gucgccguau gcaaaguacu ccaccucgaa      540

ggagaaguca acaaaaucaa auccgcccuc cuauccacaa acaaagcagu ugucucacuc      600

uccaacgggg uaagcguacu gaccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuccuuc caauccucaa caaacaauca ugcucuaucc ccaacaucga aaccguaauc      720

gaauuucaac aaaaaaacaa ccgccuacuu gaaaucacac gcgaauuuag cgucaacgca      780

ggaguaacaa cacccguguc cacauauaug cucacgaaca gcgaacuacu aucccugauu      840

aacgacaugc ccaucaccaa cgaccaaaaa aaacuaauga gcaacaacgu acaaaucguc      900

cgccaacaaa gcuacucuau aaugugcauc aucaaggaag aaguccuagc cuacgucguc      960

caauuaccac ucuacggcgu caucgacaca cccugcugga aacuccauac auccccccuc     1020

ugcaccacca acaccaaaga aggguccaac auaugccuca cucgcacaga ccgcggcugg     1080

uacugcgaca acgcuggcag cgucagcuuc uucccccagg ccgaaaccug caaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucgcucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caaaaccgac     1260

gucagcucau cagucaucac aucccucggg gccaucgucu ccugcuacgg caaaaccaag     1320

ugcaccgccu caaacaaaaa ccgcggcauu aucaaaacau ucuccaacgg cugcgacuac     1380

gucuccaaca aaggcgucga cacagucucc gucgguaaca cccucuacug cguaaauaaa     1440

caagaaggcc aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccucuc     1500

gucuuccccu ccgacgaauu ugacgccuca aucagccaag uuaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa auccgacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

accacgaaca ucaugaucac caccauaauc aucguaauua ucguaauacu ccuaucccuc     1680

auagcaguag gccuccuacu cuacugcaaa gcccguuaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  2896
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2896
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2897
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2897
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2898
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2898
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2899
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2899
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2900
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2900
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2901
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2901
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2902
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2902
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuuaaagc caaugcaaua accacaauac      120

uaacagcagu aacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

caacauguuc agcaguaagc aaaggauacc uaggagccuu acgcacaggu ugguacacuu      240

ccguaauaac aauagaacuc ucaaauauaa aagaaaacaa augcaacgga accgaugcaa      300

aaguaaaacu aauaaaacaa gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau      360

uacuuaugca aucaacaccc gcaacaggau ccggcucagc aaucuguuca ggaguagcag      420

uaugcaaagu ucuccaccua gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua      480

ccaauaaagc aguaguauca cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug      540

accuaaaaaa uuacaucgac aaacaauuac uaccaauacu uaacaaacaa ucauguucaa      600

uaccaaacau ugaaacagua auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa      660

cccgcgaauu uucaguuaac gcaggaguaa caacaccagu auccacauac auguuaacaa      720

auucagaacu cuuaucacuu auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa uguucaaaua guucgacaac aaucauacuc cauaaugugc auaauaaaag      840

aagaaguucu agcauauguu guacaacucc cacucuaugg uguuauagac acaccaugcu      900

ggaaacuaca uacaagcccc uuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacccgcac agacagaggc ugguauugcg auaacgcagg uucaguauca uucuuuccac     1020

aagcagaaac uugcaaaguc caauccaaua gagucuucug cgacacuaug aacucacuca     1080

cacucccauc ugaagucaau uuauguaacg ucgauaucuu caacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguaagcu caucagucau aacuucucua ggcgcaaucg     1200

ucucauguua cggcaaaaca aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa     1260

ccuuuucuaa cggcugcgac uacguaucaa acaaaggagu agauacugua agugucggaa     1320

acacauuaua cugcgucaac aaacaagaag gacaaucccu auauguuaaa ggcgaaccua     1380

ucauuaauuu cuacgaccca cucgucuuuc cauccgacga auuugacgca ucaauuuccc     1440

aaguaaauga aaaaauaaac caaucccuug cauucauaag aaaaucagau gaacuauuac     1500

acaacguaaa cgcaggcaaa ucaacaacaa auauaaugau cacaacaaua auaaucguaa     1560

uaauaguaau ccuacucuca cuaauagcag uaggcuuacu auuauauugc aaagccagau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2903
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2903
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuua uccuaaaagc gaacgccaua accacaaucc      120

uaacagcagu caccuucugu uucgccucag gacaaaacau caccgaggaa uuuuaccaau      180

ccacauguag cgcugucuca aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau      240

ccguaauaac gaucgaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcca      300

aagucaaacu uaucaaacaa gaacuagaca aauacaaaaa cgccgucacc gaccuccagc      360

uccucaugca auccacccca gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg      420

uaugcaaagu acuccaccuc gaaggagaag ucaacaaaau caaauccgcc cuccuaucca      480

caaacaaagc aguugucuca cucuccaacg ggguaagcgu acugaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacucc uuccaauccu caacaaacaa ucaugcucua      600

uccccaacau cgaaaccgua aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca      660

cacgcgaauu uagcgucaac gcaggaguaa caacacccgu guccacauau augcucacga      720

acagcgaacu acuaucccug auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa      780

ugagcaacaa cguacaaauc guccgccaac aaagcuacuc uauaaugugc aucaucaagg      840

aagaaguccu agccuacguc guccaauuac cacucuacgg cgucaucgac acacccugcu      900

ggaaacucca uacauccccc cucugcacca ccaacaccaa agaagggucc aacauaugcc      960

ucacucgcac agaccgcggc ugguacugcg acaacgcugg cagcgucagc uucuuccccc     1020

aggccgaaac cugcaaaguc caauccaaca gagucuucug cgacaccaug aacucgcuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacauauu caaccccaaa uacgacugca     1140

aaaucaugac cuccaaaacc gacgucagcu caucagucau cacaucccuc ggggccaucg     1200

ucuccugcua cggcaaaacc aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa     1260

cauucuccaa cggcugcgac uacgucucca acaaaggcgu cgacacaguc uccgucggua     1320

acacccucua cugcguaaau aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccu cucgucuucc ccuccgacga auuugacgcc ucaaucagcc     1440

aaguuaacga aaaaaucaac caaucacucg ccuucauccg caaauccgac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuaccacga acaucaugau caccaccaua aucaucguaa     1560

uuaucguaau acuccuaucc cucauagcag uaggccuccu acucuacugc aaagcccguu     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  2904
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2904
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2905
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2905
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2906
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2906
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2907
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2907
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2908
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2908
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2909
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2909
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2910
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2910
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uuaaagccaa ugcaauaacc acaauacuaa cagcaguaac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucaa cauguucagc aguaagcaaa      300

ggauaccuag gagccuuacg cacagguugg uacacuuccg uaauaacaau agaacucuca      360

aauauaaaag aaaacaaaug caacggaacc gaugcaaaag uaaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc aguaacagac cuacaauuac uuaugcaauc aacacccgca      480

acaggauccg gcucagcaau cuguucagga guagcaguau gcaaaguucu ccaccuagaa      540

ggcgaaguaa acaaaauaaa aucagcccua uuaucuacca auaaagcagu aguaucacua      600

ucaaauggag uaucuguccu aaccuucaaa guacuugacc uaaaaaauua caucgacaaa      660

caauuacuac caauacuuaa caaacaauca uguucaauac caaacauuga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuauua gaaauaaccc gcgaauuuuc aguuaacgca      780

ggaguaacaa caccaguauc cacauacaug uuaacaaauu cagaacucuu aucacuuaua      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu cuaacaaugu ucaaauaguu      900

cgacaacaau cauacuccau aaugugcaua auaaaagaag aaguucuagc auauguugua      960

caacucccac ucuauggugu uauagacaca ccaugcugga aacuacauac aagccccuua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa cccgcacaga cagaggcugg     1080

uauugcgaua acgcagguuc aguaucauuc uuuccacaag cagaaacuug caaaguccaa     1140

uccaauagag ucuucugcga cacuaugaac ucacucacac ucccaucuga agucaauuua     1200

uguaacgucg auaucuucaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guaagcucau cagucauaac uucucuaggc gcaaucgucu cauguuacgg caaaacaaaa     1320

uguaccgcau caaacaaaaa ucgagguaua auaaaaaccu uuucuaacgg cugcgacuac     1380

guaucaaaca aaggaguaga uacuguaagu gucggaaaca cauuauacug cgucaacaaa     1440

caagaaggac aaucccuaua uguuaaaggc gaaccuauca uuaauuucua cgacccacuc     1500

gucuuuccau ccgacgaauu ugacgcauca auuucccaag uaaaugaaaa aauaaaccaa     1560

ucccuugcau ucauaagaaa aucagaugaa cuauuacaca acguaaacgc aggcaaauca     1620

acaacaaaua uaaugaucac aacaauaaua aucguaauaa uaguaauccu acucucacua     1680

auagcaguag gcuuacuauu auauugcaaa gccagauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2911
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2911
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuuaucc uaaaagcgaa cgccauaacc acaauccuaa cagcagucac cuucuguuuc      240

gccucaggac aaaacaucac cgaggaauuu uaccaaucca cauguagcgc ugucucaaaa      300

ggcuaccucg gcgcccuccg aaccggcugg uacacauccg uaauaacgau cgaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgccaaag ucaaacuuau caaacaagaa      420

cuagacaaau acaaaaacgc cgucaccgac cuccagcucc ucaugcaauc caccccagca      480

acaggcuccg gaagcgcaau cugcucaggc gucgccguau gcaaaguacu ccaccucgaa      540

ggagaaguca acaaaaucaa auccgcccuc cuauccacaa acaaagcagu ugucucacuc      600

uccaacgggg uaagcguacu gaccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuccuuc caauccucaa caaacaauca ugcucuaucc ccaacaucga aaccguaauc      720

gaauuucaac aaaaaaacaa ccgccuacuu gaaaucacac gcgaauuuag cgucaacgca      780

ggaguaacaa cacccguguc cacauauaug cucacgaaca gcgaacuacu aucccugauu      840

aacgacaugc ccaucaccaa cgaccaaaaa aaacuaauga gcaacaacgu acaaaucguc      900

cgccaacaaa gcuacucuau aaugugcauc aucaaggaag aaguccuagc cuacgucguc      960

caauuaccac ucuacggcgu caucgacaca cccugcugga aacuccauac auccccccuc     1020

ugcaccacca acaccaaaga aggguccaac auaugccuca cucgcacaga ccgcggcugg     1080

uacugcgaca acgcuggcag cgucagcuuc uucccccagg ccgaaaccug caaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucgcucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caaaaccgac     1260

gucagcucau cagucaucac aucccucggg gccaucgucu ccugcuacgg caaaaccaag     1320

ugcaccgccu caaacaaaaa ccgcggcauu aucaaaacau ucuccaacgg cugcgacuac     1380

gucuccaaca aaggcgucga cacagucucc gucgguaaca cccucuacug cguaaauaaa     1440

caagaaggcc aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccucuc     1500

gucuuccccu ccgacgaauu ugacgccuca aucagccaag uuaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa auccgacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

accacgaaca ucaugaucac caccauaauc aucguaauua ucguaauacu ccuaucccuc     1680

auagcaguag gccuccuacu cuacugcaaa gcccguuaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  2912
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2912
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2913
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2913
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      540

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1380

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2914
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2914
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2915
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2915
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      480

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      540

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      600

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      720

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      780

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      840

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua      900

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc      960

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg     1020

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1080

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1140

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1200

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1260

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1320

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1380

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1440

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1500

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1560

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1620

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2916
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2916
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2917
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2917
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      480

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      540

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      600

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      720

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      780

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      840

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug      900

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      960

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc     1020

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1080

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1140

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1200

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1260

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1320

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1380

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1440

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1500

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1620

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2918
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2918
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuaa uacuuaaagc caaugcaaua accacaauac uaacagcagu aacauucugc      180

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau caacauguuc agcaguaagc      240

aaaggauacc uaggagccuu acgcacaggu ugguacacuu ccguaauaac aauagaacuc      300

ucaaauauaa aagaaaacaa augcaacgga accgaugcaa aaguaaaacu aauaaaacaa      360

gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau uacuuaugca aucaacaccc      420

gcaacaggau ccggcucagc aaucuguuca ggaguagcag uaugcaaagu ucuccaccua      480

gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua ccaauaaagc aguaguauca      540

cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug accuaaaaaa uuacaucgac      600

aaacaauuac uaccaauacu uaacaaacaa ucauguucaa uaccaaacau ugaaacagua      660

auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa cccgcgaauu uucaguuaac      720

gcaggaguaa caacaccagu auccacauac auguuaacaa auucagaacu cuuaucacuu      780

auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca ugucuaacaa uguucaaaua      840

guucgacaac aaucauacuc cauaaugugc auaauaaaag aagaaguucu agcauauguu      900

guacaacucc cacucuaugg uguuauagac acaccaugcu ggaaacuaca uacaagcccc      960

uuaugcacua caaacacaaa agaaggcucu aauauauguc uaacccgcac agacagaggc     1020

ugguauugcg auaacgcagg uucaguauca uucuuuccac aagcagaaac uugcaaaguc     1080

caauccaaua gagucuucug cgacacuaug aacucacuca cacucccauc ugaagucaau     1140

uuauguaacg ucgauaucuu caacccaaaa uacgacugca aaauaaugac cucaaaaaca     1200

gacguaagcu caucagucau aacuucucua ggcgcaaucg ucucauguua cggcaaaaca     1260

aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa ccuuuucuaa cggcugcgac     1320

uacguaucaa acaaaggagu agauacugua agugucggaa acacauuaua cugcgucaac     1380

aaacaagaag gacaaucccu auauguuaaa ggcgaaccua ucauuaauuu cuacgaccca     1440

cucgucuuuc cauccgacga auuugacgca ucaauuuccc aaguaaauga aaaaauaaac     1500

caaucccuug cauucauaag aaaaucagau gaacuauuac acaacguaaa cgcaggcaaa     1560

ucaacaacaa auauaaugau cacaacaaua auaaucguaa uaauaguaau ccuacucuca     1620

cuaauagcag uaggcuuacu auuauauugc aaagccagau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2919
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2919
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuucuua uccuaaaagc gaacgccaua accacaaucc uaacagcagu caccuucugu      180

uucgccucag gacaaaacau caccgaggaa uuuuaccaau ccacauguag cgcugucuca      240

aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau ccguaauaac gaucgaacuc      300

uccaacauaa aagaaaauaa augcaacggc accgacgcca aagucaaacu uaucaaacaa      360

gaacuagaca aauacaaaaa cgccgucacc gaccuccagc uccucaugca auccacccca      420

gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg uaugcaaagu acuccaccuc      480

gaaggagaag ucaacaaaau caaauccgcc cuccuaucca caaacaaagc aguugucuca      540

cucuccaacg ggguaagcgu acugaccuuc aaaguccuag accucaaaaa cuacaucgau      600

aaacaacucc uuccaauccu caacaaacaa ucaugcucua uccccaacau cgaaaccgua      660

aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca cacgcgaauu uagcgucaac      720

gcaggaguaa caacacccgu guccacauau augcucacga acagcgaacu acuaucccug      780

auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa ugagcaacaa cguacaaauc      840

guccgccaac aaagcuacuc uauaaugugc aucaucaagg aagaaguccu agccuacguc      900

guccaauuac cacucuacgg cgucaucgac acacccugcu ggaaacucca uacauccccc      960

cucugcacca ccaacaccaa agaagggucc aacauaugcc ucacucgcac agaccgcggc     1020

ugguacugcg acaacgcugg cagcgucagc uucuuccccc aggccgaaac cugcaaaguc     1080

caauccaaca gagucuucug cgacaccaug aacucgcuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacauauu caaccccaaa uacgacugca aaaucaugac cuccaaaacc     1200

gacgucagcu caucagucau cacaucccuc ggggccaucg ucuccugcua cggcaaaacc     1260

aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa cauucuccaa cggcugcgac     1320

uacgucucca acaaaggcgu cgacacaguc uccgucggua acacccucua cugcguaaau     1380

aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccu     1440

cucgucuucc ccuccgacga auuugacgcc ucaaucagcc aaguuaacga aaaaaucaac     1500

caaucacucg ccuucauccg caaauccgac gaacuccucc acaacguuaa cgccggcaaa     1560

ucuaccacga acaucaugau caccaccaua aucaucguaa uuaucguaau acuccuaucc     1620

cucauagcag uaggccuccu acucuacugc aaagcccguu aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  2920
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2920
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2921
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2921
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2922
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2922
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2923
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2923
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2924
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2924
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2925
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2925
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2926
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2926
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuuaaa      120

gccaaugcaa uaaccacaau acuaacagca guaacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca aucaacaugu ucagcaguaa gcaaaggaua ccuaggagcc      240

uuacgcacag guugguacac uuccguaaua acaauagaac ucucaaauau aaaagaaaac      300

aaaugcaacg gaaccgaugc aaaaguaaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgcaguaa cagaccuaca auuacuuaug caaucaacac ccgcaacagg auccggcuca      420

gcaaucuguu caggaguagc aguaugcaaa guucuccacc uagaaggcga aguaaacaaa      480

auaaaaucag cccuauuauc uaccaauaaa gcaguaguau cacuaucaaa uggaguaucu      540

guccuaaccu ucaaaguacu ugaccuaaaa aauuacaucg acaaacaauu acuaccaaua      600

cuuaacaaac aaucauguuc aauaccaaac auugaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uauuagaaau aacccgcgaa uuuucaguua acgcaggagu aacaacacca      720

guauccacau acauguuaac aaauucagaa cucuuaucac uuauaaacga caugcccaua      780

acaaacgacc aaaaaaaacu caugucuaac aauguucaaa uaguucgaca acaaucauac      840

uccauaaugu gcauaauaaa agaagaaguu cuagcauaug uuguacaacu cccacucuau      900

gguguuauag acacaccaug cuggaaacua cauacaagcc ccuuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacccgc acagacagag gcugguauug cgauaacgca     1020

gguucaguau cauucuuucc acaagcagaa acuugcaaag uccaauccaa uagagucuuc     1080

ugcgacacua ugaacucacu cacacuccca ucugaaguca auuuauguaa cgucgauauc     1140

uucaacccaa aauacgacug caaaauaaug accucaaaaa cagacguaag cucaucaguc     1200

auaacuucuc uaggcgcaau cgucucaugu uacggcaaaa caaaauguac cgcaucaaac     1260

aaaaaucgag guauaauaaa aaccuuuucu aacggcugcg acuacguauc aaacaaagga     1320

guagauacug uaagugucgg aaacacauua uacugcguca acaaacaaga aggacaaucc     1380

cuauauguua aaggcgaacc uaucauuaau uucuacgacc cacucgucuu uccauccgac     1440

gaauuugacg caucaauuuc ccaaguaaau gaaaaaauaa accaaucccu ugcauucaua     1500

agaaaaucag augaacuauu acacaacgua aacgcaggca aaucaacaac aaauauaaug     1560

aucacaacaa uaauaaucgu aauaauagua auccuacucu cacuaauagc aguaggcuua     1620

cuauuauauu gcaaagccag auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2927
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2927
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu uauccuaaaa      120

gcgaacgcca uaaccacaau ccuaacagca gucaccuucu guuucgccuc aggacaaaac      180

aucaccgagg aauuuuacca auccacaugu agcgcugucu caaaaggcua ccucggcgcc      240

cuccgaaccg gcugguacac auccguaaua acgaucgaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc caaagucaaa cuuaucaaac aagaacuaga caaauacaaa      360

aacgccguca ccgaccucca gcuccucaug caauccaccc cagcaacagg cuccggaagc      420

gcaaucugcu caggcgucgc cguaugcaaa guacuccacc ucgaaggaga agucaacaaa      480

aucaaauccg cccuccuauc cacaaacaaa gcaguugucu cacucuccaa cgggguaagc      540

guacugaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu ccuuccaauc      600

cucaacaaac aaucaugcuc uauccccaac aucgaaaccg uaaucgaauu ucaacaaaaa      660

aacaaccgcc uacuugaaau cacacgcgaa uuuagcguca acgcaggagu aacaacaccc      720

guguccacau auaugcucac gaacagcgaa cuacuauccc ugauuaacga caugcccauc      780

accaacgacc aaaaaaaacu aaugagcaac aacguacaaa ucguccgcca acaaagcuac      840

ucuauaaugu gcaucaucaa ggaagaaguc cuagccuacg ucguccaauu accacucuac      900

ggcgucaucg acacacccug cuggaaacuc cauacauccc cccucugcac caccaacacc      960

aaagaagggu ccaacauaug ccucacucgc acagaccgcg gcugguacug cgacaacgcu     1020

ggcagcguca gcuucuuccc ccaggccgaa accugcaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucgcu cacccucccc uccgagguca accucugcaa cgucgacaua     1140

uucaacccca aauacgacug caaaaucaug accuccaaaa ccgacgucag cucaucaguc     1200

aucacauccc ucggggccau cgucuccugc uacggcaaaa ccaagugcac cgccucaaac     1260

aaaaaccgcg gcauuaucaa aacauucucc aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag ucuccgucgg uaacacccuc uacugcguaa auaaacaaga aggccaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cucucgucuu ccccuccgac     1440

gaauuugacg ccucaaucag ccaaguuaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaauccg acgaacuccu ccacaacguu aacgccggca aaucuaccac gaacaucaug     1560

aucaccacca uaaucaucgu aauuaucgua auacuccuau cccucauagc aguaggccuc     1620

cuacucuacu gcaaagcccg uuaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  2928
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2928
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2929
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2929
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2930
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2930
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2931
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2931
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2932
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2932
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2933
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2933
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2934
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2934
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuuaaa gccaaugcaa uaaccacaau acuaacagca      120

guaacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca aucaacaugu      180

ucagcaguaa gcaaaggaua ccuaggagcc uuacgcacag guugguacac uuccguaaua      240

acaauagaac ucucaaauau aaaagaaaac aaaugcaacg gaaccgaugc aaaaguaaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgcaguaa cagaccuaca auuacuuaug      360

caaucaacac ccgcaacagg auccggcuca gcaaucuguu caggaguagc aguaugcaaa      420

guucuccacc uagaaggcga aguaaacaaa auaaaaucag cccuauuauc uaccaauaaa      480

gcaguaguau cacuaucaaa uggaguaucu guccuaaccu ucaaaguacu ugaccuaaaa      540

aauuacaucg acaaacaauu acuaccaaua cuuaacaaac aaucauguuc aauaccaaac      600

auugaaacag uaauagaauu ucaacaaaaa aauaacagau uauuagaaau aacccgcgaa      660

uuuucaguua acgcaggagu aacaacacca guauccacau acauguuaac aaauucagaa      720

cucuuaucac uuauaaacga caugcccaua acaaacgacc aaaaaaaacu caugucuaac      780

aauguucaaa uaguucgaca acaaucauac uccauaaugu gcauaauaaa agaagaaguu      840

cuagcauaug uuguacaacu cccacucuau gguguuauag acacaccaug cuggaaacua      900

cauacaagcc ccuuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacccgc      960

acagacagag gcugguauug cgauaacgca gguucaguau cauucuuucc acaagcagaa     1020

acuugcaaag uccaauccaa uagagucuuc ugcgacacua ugaacucacu cacacuccca     1080

ucugaaguca auuuauguaa cgucgauauc uucaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguaag cucaucaguc auaacuucuc uaggcgcaau cgucucaugu     1200

uacggcaaaa caaaauguac cgcaucaaac aaaaaucgag guauaauaaa aaccuuuucu     1260

aacggcugcg acuacguauc aaacaaagga guagauacug uaagugucgg aaacacauua     1320

uacugcguca acaaacaaga aggacaaucc cuauauguua aaggcgaacc uaucauuaau     1380

uucuacgacc cacucgucuu uccauccgac gaauuugacg caucaauuuc ccaaguaaau     1440

gaaaaaauaa accaaucccu ugcauucaua agaaaaucag augaacuauu acacaacgua     1500

aacgcaggca aaucaacaac aaauauaaug aucacaacaa uaauaaucgu aauaauagua     1560

auccuacucu cacuaauagc aguaggcuua cuauuauauu gcaaagccag auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2935
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2935
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu uauccuaaaa gcgaacgcca uaaccacaau ccuaacagca      120

gucaccuucu guuucgccuc aggacaaaac aucaccgagg aauuuuacca auccacaugu      180

agcgcugucu caaaaggcua ccucggcgcc cuccgaaccg gcugguacac auccguaaua      240

acgaucgaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc caaagucaaa      300

cuuaucaaac aagaacuaga caaauacaaa aacgccguca ccgaccucca gcuccucaug      360

caauccaccc cagcaacagg cuccggaagc gcaaucugcu caggcgucgc cguaugcaaa      420

guacuccacc ucgaaggaga agucaacaaa aucaaauccg cccuccuauc cacaaacaaa      480

gcaguugucu cacucuccaa cgggguaagc guacugaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu ccuuccaauc cucaacaaac aaucaugcuc uauccccaac      600

aucgaaaccg uaaucgaauu ucaacaaaaa aacaaccgcc uacuugaaau cacacgcgaa      660

uuuagcguca acgcaggagu aacaacaccc guguccacau auaugcucac gaacagcgaa      720

cuacuauccc ugauuaacga caugcccauc accaacgacc aaaaaaaacu aaugagcaac      780

aacguacaaa ucguccgcca acaaagcuac ucuauaaugu gcaucaucaa ggaagaaguc      840

cuagccuacg ucguccaauu accacucuac ggcgucaucg acacacccug cuggaaacuc      900

cauacauccc cccucugcac caccaacacc aaagaagggu ccaacauaug ccucacucgc      960

acagaccgcg gcugguacug cgacaacgcu ggcagcguca gcuucuuccc ccaggccgaa     1020

accugcaaag uccaauccaa cagagucuuc ugcgacacca ugaacucgcu cacccucccc     1080

uccgagguca accucugcaa cgucgacaua uucaacccca aauacgacug caaaaucaug     1140

accuccaaaa ccgacgucag cucaucaguc aucacauccc ucggggccau cgucuccugc     1200

uacggcaaaa ccaagugcac cgccucaaac aaaaaccgcg gcauuaucaa aacauucucc     1260

aacggcugcg acuacgucuc caacaaaggc gucgacacag ucuccgucgg uaacacccuc     1320

uacugcguaa auaaacaaga aggccaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cucucgucuu ccccuccgac gaauuugacg ccucaaucag ccaaguuaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaauccg acgaacuccu ccacaacguu     1500

aacgccggca aaucuaccac gaacaucaug aucaccacca uaaucaucgu aauuaucgua     1560

auacuccuau cccucauagc aguaggccuc cuacucuacu gcaaagcccg uuaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  2936
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2936
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2937
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2937
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2938
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2938
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2939
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2939
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2940
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2940
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2941
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2941
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2942
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2942
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu uaaagccaau gcaauaacca caauacuaac agcaguaaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaaucaac auguucagca      240

guaagcaaag gauaccuagg agccuuacgc acagguuggu acacuuccgu aauaacaaua      300

gaacucucaa auauaaaaga aaacaaaugc aacggaaccg augcaaaagu aaaacuaaua      360

aaacaagaau uagacaaaua caaaaacgca guaacagacc uacaauuacu uaugcaauca      420

acacccgcaa caggauccgg cucagcaauc uguucaggag uagcaguaug caaaguucuc      480

caccuagaag gcgaaguaaa caaaauaaaa ucagcccuau uaucuaccaa uaaagcagua      540

guaucacuau caaauggagu aucuguccua accuucaaag uacuugaccu aaaaaauuac      600

aucgacaaac aauuacuacc aauacuuaac aaacaaucau guucaauacc aaacauugaa      660

acaguaauag aauuucaaca aaaaaauaac agauuauuag aaauaacccg cgaauuuuca      720

guuaacgcag gaguaacaac accaguaucc acauacaugu uaacaaauuc agaacucuua      780

ucacuuauaa acgacaugcc cauaacaaac gaccaaaaaa aacucauguc uaacaauguu      840

caaauaguuc gacaacaauc auacuccaua augugcauaa uaaaagaaga aguucuagca      900

uauguuguac aacucccacu cuaugguguu auagacacac caugcuggaa acuacauaca      960

agccccuuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac ccgcacagac     1020

agaggcuggu auugcgauaa cgcagguuca guaucauucu uuccacaagc agaaacuugc     1080

aaaguccaau ccaauagagu cuucugcgac acuaugaacu cacucacacu cccaucugaa     1140

gucaauuuau guaacgucga uaucuucaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uaagcucauc agucauaacu ucucuaggcg caaucgucuc auguuacggc     1260

aaaacaaaau guaccgcauc aaacaaaaau cgagguauaa uaaaaaccuu uucuaacggc     1320

ugcgacuacg uaucaaacaa aggaguagau acuguaagug ucggaaacac auuauacugc     1380

gucaacaaac aagaaggaca aucccuauau guuaaaggcg aaccuaucau uaauuucuac     1440

gacccacucg ucuuuccauc cgacgaauuu gacgcaucaa uuucccaagu aaaugaaaaa     1500

auaaaccaau cccuugcauu cauaagaaaa ucagaugaac uauuacacaa cguaaacgca     1560

ggcaaaucaa caacaaauau aaugaucaca acaauaauaa ucguaauaau aguaauccua     1620

cucucacuaa uagcaguagg cuuacuauua uauugcaaag ccagauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2943
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2943
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuuauccu aaaagcgaac gccauaacca caauccuaac agcagucacc      180

uucuguuucg ccucaggaca aaacaucacc gaggaauuuu accaauccac auguagcgcu      240

gucucaaaag gcuaccucgg cgcccuccga accggcuggu acacauccgu aauaacgauc      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgccaaagu caaacuuauc      360

aaacaagaac uagacaaaua caaaaacgcc gucaccgacc uccagcuccu caugcaaucc      420

accccagcaa caggcuccgg aagcgcaauc ugcucaggcg ucgccguaug caaaguacuc      480

caccucgaag gagaagucaa caaaaucaaa uccgcccucc uauccacaaa caaagcaguu      540

gucucacucu ccaacggggu aagcguacug accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuccuucc aauccucaac aaacaaucau gcucuauccc caacaucgaa      660

accguaaucg aauuucaaca aaaaaacaac cgccuacuug aaaucacacg cgaauuuagc      720

gucaacgcag gaguaacaac acccgugucc acauauaugc ucacgaacag cgaacuacua      780

ucccugauua acgacaugcc caucaccaac gaccaaaaaa aacuaaugag caacaacgua      840

caaaucgucc gccaacaaag cuacucuaua augugcauca ucaaggaaga aguccuagcc      900

uacgucgucc aauuaccacu cuacggcguc aucgacacac ccugcuggaa acuccauaca      960

uccccccucu gcaccaccaa caccaaagaa ggguccaaca uaugccucac ucgcacagac     1020

cgcggcuggu acugcgacaa cgcuggcagc gucagcuucu ucccccaggc cgaaaccugc     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cgcucacccu ccccuccgag     1140

gucaaccucu gcaacgucga cauauucaac cccaaauacg acugcaaaau caugaccucc     1200

aaaaccgacg ucagcucauc agucaucaca ucccucgggg ccaucgucuc cugcuacggc     1260

aaaaccaagu gcaccgccuc aaacaaaaac cgcggcauua ucaaaacauu cuccaacggc     1320

ugcgacuacg ucuccaacaa aggcgucgac acagucuccg ucgguaacac ccucuacugc     1380

guaaauaaac aagaaggcca aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccucucg ucuuccccuc cgacgaauuu gacgccucaa ucagccaagu uaacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa uccgacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua ccacgaacau caugaucacc accauaauca ucguaauuau cguaauacuc     1620

cuaucccuca uagcaguagg ccuccuacuc uacugcaaag cccguuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  2944
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2944
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2945
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2945
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2946
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2946
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2947
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2947
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2948
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2948
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2949
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2949
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2950
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2950
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuuaa agccaaugca      120

auaaccacaa uacuaacagc aguaacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aaucaacaug uucagcagua agcaaaggau accuaggagc cuuacgcaca      240

gguugguaca cuuccguaau aacaauagaa cucucaaaua uaaaagaaaa caaaugcaac      300

ggaaccgaug caaaaguaaa acuaauaaaa caagaauuag acaaauacaa aaacgcagua      360

acagaccuac aauuacuuau gcaaucaaca cccgcaacag gauccggcuc agcaaucugu      420

ucaggaguag caguaugcaa aguucuccac cuagaaggcg aaguaaacaa aauaaaauca      480

gcccuauuau cuaccaauaa agcaguagua ucacuaucaa auggaguauc uguccuaacc      540

uucaaaguac uugaccuaaa aaauuacauc gacaaacaau uacuaccaau acuuaacaaa      600

caaucauguu caauaccaaa cauugaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuauuagaaa uaacccgcga auuuucaguu aacgcaggag uaacaacacc aguauccaca      720

uacauguuaa caaauucaga acucuuauca cuuauaaacg acaugcccau aacaaacgac      780

caaaaaaaac ucaugucuaa caauguucaa auaguucgac aacaaucaua cuccauaaug      840

ugcauaauaa aagaagaagu ucuagcauau guuguacaac ucccacucua ugguguuaua      900

gacacaccau gcuggaaacu acauacaagc cccuuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacccg cacagacaga ggcugguauu gcgauaacgc agguucagua     1020

ucauucuuuc cacaagcaga aacuugcaaa guccaaucca auagagucuu cugcgacacu     1080

augaacucac ucacacuccc aucugaaguc aauuuaugua acgucgauau cuucaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguaa gcucaucagu cauaacuucu     1200

cuaggcgcaa ucgucucaug uuacggcaaa acaaaaugua ccgcaucaaa caaaaaucga     1260

gguauaauaa aaaccuuuuc uaacggcugc gacuacguau caaacaaagg aguagauacu     1320

guaagugucg gaaacacauu auacugcguc aacaaacaag aaggacaauc ccuauauguu     1380

aaaggcgaac cuaucauuaa uuucuacgac ccacucgucu uuccauccga cgaauuugac     1440

gcaucaauuu cccaaguaaa ugaaaaaaua aaccaauccc uugcauucau aagaaaauca     1500

gaugaacuau uacacaacgu aaacgcaggc aaaucaacaa caaauauaau gaucacaaca     1560

auaauaaucg uaauaauagu aauccuacuc ucacuaauag caguaggcuu acuauuauau     1620

ugcaaagcca gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2951
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2951
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uuauccuaaa agcgaacgcc      120

auaaccacaa uccuaacagc agucaccuuc uguuucgccu caggacaaaa caucaccgag      180

gaauuuuacc aauccacaug uagcgcuguc ucaaaaggcu accucggcgc ccuccgaacc      240

ggcugguaca cauccguaau aacgaucgaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg ccaaagucaa acuuaucaaa caagaacuag acaaauacaa aaacgccguc      360

accgaccucc agcuccucau gcaauccacc ccagcaacag gcuccggaag cgcaaucugc      420

ucaggcgucg ccguaugcaa aguacuccac cucgaaggag aagucaacaa aaucaaaucc      480

gcccuccuau ccacaaacaa agcaguuguc ucacucucca acgggguaag cguacugacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uccuuccaau ccucaacaaa      600

caaucaugcu cuauccccaa caucgaaacc guaaucgaau uucaacaaaa aaacaaccgc      660

cuacuugaaa ucacacgcga auuuagcguc aacgcaggag uaacaacacc cguguccaca      720

uauaugcuca cgaacagcga acuacuaucc cugauuaacg acaugcccau caccaacgac      780

caaaaaaaac uaaugagcaa caacguacaa aucguccgcc aacaaagcua cucuauaaug      840

ugcaucauca aggaagaagu ccuagccuac gucguccaau uaccacucua cggcgucauc      900

gacacacccu gcuggaaacu ccauacaucc ccccucugca ccaccaacac caaagaaggg      960

uccaacauau gccucacucg cacagaccgc ggcugguacu gcgacaacgc uggcagcguc     1020

agcuucuucc cccaggccga aaccugcaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucgc ucacccuccc cuccgagguc aaccucugca acgucgacau auucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaaa accgacguca gcucaucagu caucacaucc     1200

cucggggcca ucgucuccug cuacggcaaa accaagugca ccgccucaaa caaaaaccgc     1260

ggcauuauca aaacauucuc caacggcugc gacuacgucu ccaacaaagg cgucgacaca     1320

gucuccgucg guaacacccu cuacugcgua aauaaacaag aaggccaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccucucgucu uccccuccga cgaauuugac     1440

gccucaauca gccaaguuaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaucc     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacca cgaacaucau gaucaccacc     1560

auaaucaucg uaauuaucgu aauacuccua ucccucauag caguaggccu ccuacucuac     1620

ugcaaagccc guuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  2952
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2952
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2953
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2953
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2954
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2954
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2955
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2955
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2956
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2956
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2957
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2957
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2958
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2958
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuuaa agccaaugca      120

auaaccacaa uacuaacagc aguaacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aaucaacaug uucagcagua agcaaaggau accuaggagc cuuacgcaca      240

gguugguaca cuuccguaau aacaauagaa cucucaaaua uaaaagaaaa caaaugcaac      300

ggaaccgaug caaaaguaaa acuaauaaaa caagaauuag acaaauacaa aaacgcagua      360

acagaccuac aauuacuuau gcaaucaaca cccgcaacag gauccggcuc agcaaucugu      420

ucaggaguag caguaugcaa aguucuccac cuagaaggcg aaguaaacaa aauaaaauca      480

gcccuauuau cuaccaauaa agcaguagua ucacuaucaa auggaguauc uguccuaacc      540

uucaaaguac uugaccuaaa aaauuacauc gacaaacaau uacuaccaau acuuaacaaa      600

caaucauguu caauaccaaa cauugaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuauuagaaa uaacccgcga auuuucaguu aacgcaggag uaacaacacc aguauccaca      720

uacauguuaa caaauucaga acucuuauca cuuauaaacg acaugcccau aacaaacgac      780

caaaaaaaac ucaugucuaa caauguucaa auaguucgac aacaaucaua cuccauaaug      840

ugcauaauaa aagaagaagu ucuagcauau guuguacaac ucccacucua ugguguuaua      900

gacacaccau gcuggaaacu acauacaagc cccuuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacccg cacagacaga ggcugguauu gcgauaacgc agguucagua     1020

ucauucuuuc cacaagcaga aacuugcaaa guccaaucca auagagucuu cugcgacacu     1080

augaacucac ucacacuccc aucugaaguc aauuuaugua acgucgauau cuucaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguaa gcucaucagu cauaacuucu     1200

cuaggcgcaa ucgucucaug uuacggcaaa acaaaaugua ccgcaucaaa caaaaaucga     1260

gguauaauaa aaaccuuuuc uaacggcugc gacuacguau caaacaaagg aguagauacu     1320

guaagugucg gaaacacauu auacugcguc aacaaacaag aaggacaauc ccuauauguu     1380

aaaggcgaac cuaucauuaa uuucuacgac ccacucgucu uuccauccga cgaauuugac     1440

gcaucaauuu cccaaguaaa ugaaaaaaua aaccaauccc uugcauucau aagaaaauca     1500

gaugaacuau uacacaacgu aaacgcaggc aaaucaacaa caaauauaau gaucacaaca     1560

auaauaaucg uaauaauagu aauccuacuc ucacuaauag caguaggcuu acuauuauau     1620

ugcaaagcca gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2959
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2959
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uuauccuaaa agcgaacgcc      120

auaaccacaa uccuaacagc agucaccuuc uguuucgccu caggacaaaa caucaccgag      180

gaauuuuacc aauccacaug uagcgcuguc ucaaaaggcu accucggcgc ccuccgaacc      240

ggcugguaca cauccguaau aacgaucgaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg ccaaagucaa acuuaucaaa caagaacuag acaaauacaa aaacgccguc      360

accgaccucc agcuccucau gcaauccacc ccagcaacag gcuccggaag cgcaaucugc      420

ucaggcgucg ccguaugcaa aguacuccac cucgaaggag aagucaacaa aaucaaaucc      480

gcccuccuau ccacaaacaa agcaguuguc ucacucucca acgggguaag cguacugacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uccuuccaau ccucaacaaa      600

caaucaugcu cuauccccaa caucgaaacc guaaucgaau uucaacaaaa aaacaaccgc      660

cuacuugaaa ucacacgcga auuuagcguc aacgcaggag uaacaacacc cguguccaca      720

uauaugcuca cgaacagcga acuacuaucc cugauuaacg acaugcccau caccaacgac      780

caaaaaaaac uaaugagcaa caacguacaa aucguccgcc aacaaagcua cucuauaaug      840

ugcaucauca aggaagaagu ccuagccuac gucguccaau uaccacucua cggcgucauc      900

gacacacccu gcuggaaacu ccauacaucc ccccucugca ccaccaacac caaagaaggg      960

uccaacauau gccucacucg cacagaccgc ggcugguacu gcgacaacgc uggcagcguc     1020

agcuucuucc cccaggccga aaccugcaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucgc ucacccuccc cuccgagguc aaccucugca acgucgacau auucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaaa accgacguca gcucaucagu caucacaucc     1200

cucggggcca ucgucuccug cuacggcaaa accaagugca ccgccucaaa caaaaaccgc     1260

ggcauuauca aaacauucuc caacggcugc gacuacgucu ccaacaaagg cgucgacaca     1320

gucuccgucg guaacacccu cuacugcgua aauaaacaag aaggccaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccucucgucu uccccuccga cgaauuugac     1440

gccucaauca gccaaguuaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaucc     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacca cgaacaucau gaucaccacc     1560

auaaucaucg uaauuaucgu aauacuccua ucccucauag caguaggccu ccuacucuac     1620

ugcaaagccc guuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  2960
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2960
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2961
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2961
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2962
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2962
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2963
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2963
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2964
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2964
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2965
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2965
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2966
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2966
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuuaa agccaaugca      120

auaaccacaa uacuaacagc aguaacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aaucaacaug uucagcagua agcaaaggau accuaggagc cuuacgcaca      240

gguugguaca cuuccguaau aacaauagaa cucucaaaua uaaaagaaaa caaaugcaac      300

ggaaccgaug caaaaguaaa acuaauaaaa caagaauuag acaaauacaa aaacgcagua      360

acagaccuac aauuacuuau gcaaucaaca cccgcaacag gauccggcuc agcaaucugu      420

ucaggaguag caguaugcaa aguucuccac cuagaaggcg aaguaaacaa aauaaaauca      480

gcccuauuau cuaccaauaa agcaguagua ucacuaucaa auggaguauc uguccuaacc      540

uucaaaguac uugaccuaaa aaauuacauc gacaaacaau uacuaccaau acuuaacaaa      600

caaucauguu caauaccaaa cauugaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuauuagaaa uaacccgcga auuuucaguu aacgcaggag uaacaacacc aguauccaca      720

uacauguuaa caaauucaga acucuuauca cuuauaaacg acaugcccau aacaaacgac      780

caaaaaaaac ucaugucuaa caauguucaa auaguucgac aacaaucaua cuccauaaug      840

ugcauaauaa aagaagaagu ucuagcauau guuguacaac ucccacucua ugguguuaua      900

gacacaccau gcuggaaacu acauacaagc cccuuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacccg cacagacaga ggcugguauu gcgauaacgc agguucagua     1020

ucauucuuuc cacaagcaga aacuugcaaa guccaaucca auagagucuu cugcgacacu     1080

augaacucac ucacacuccc aucugaaguc aauuuaugua acgucgauau cuucaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguaa gcucaucagu cauaacuucu     1200

cuaggcgcaa ucgucucaug uuacggcaaa acaaaaugua ccgcaucaaa caaaaaucga     1260

gguauaauaa aaaccuuuuc uaacggcugc gacuacguau caaacaaagg aguagauacu     1320

guaagugucg gaaacacauu auacugcguc aacaaacaag aaggacaauc ccuauauguu     1380

aaaggcgaac cuaucauuaa uuucuacgac ccacucgucu uuccauccga cgaauuugac     1440

gcaucaauuu cccaaguaaa ugaaaaaaua aaccaauccc uugcauucau aagaaaauca     1500

gaugaacuau uacacaacgu aaacgcaggc aaaucaacaa caaauauaau gaucacaaca     1560

auaauaaucg uaauaauagu aauccuacuc ucacuaauag caguaggcuu acuauuauau     1620

ugcaaagcca gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2967
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2967
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uuauccuaaa agcgaacgcc      120

auaaccacaa uccuaacagc agucaccuuc uguuucgccu caggacaaaa caucaccgag      180

gaauuuuacc aauccacaug uagcgcuguc ucaaaaggcu accucggcgc ccuccgaacc      240

ggcugguaca cauccguaau aacgaucgaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg ccaaagucaa acuuaucaaa caagaacuag acaaauacaa aaacgccguc      360

accgaccucc agcuccucau gcaauccacc ccagcaacag gcuccggaag cgcaaucugc      420

ucaggcgucg ccguaugcaa aguacuccac cucgaaggag aagucaacaa aaucaaaucc      480

gcccuccuau ccacaaacaa agcaguuguc ucacucucca acgggguaag cguacugacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uccuuccaau ccucaacaaa      600

caaucaugcu cuauccccaa caucgaaacc guaaucgaau uucaacaaaa aaacaaccgc      660

cuacuugaaa ucacacgcga auuuagcguc aacgcaggag uaacaacacc cguguccaca      720

uauaugcuca cgaacagcga acuacuaucc cugauuaacg acaugcccau caccaacgac      780

caaaaaaaac uaaugagcaa caacguacaa aucguccgcc aacaaagcua cucuauaaug      840

ugcaucauca aggaagaagu ccuagccuac gucguccaau uaccacucua cggcgucauc      900

gacacacccu gcuggaaacu ccauacaucc ccccucugca ccaccaacac caaagaaggg      960

uccaacauau gccucacucg cacagaccgc ggcugguacu gcgacaacgc uggcagcguc     1020

agcuucuucc cccaggccga aaccugcaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucgc ucacccuccc cuccgagguc aaccucugca acgucgacau auucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaaa accgacguca gcucaucagu caucacaucc     1200

cucggggcca ucgucuccug cuacggcaaa accaagugca ccgccucaaa caaaaaccgc     1260

ggcauuauca aaacauucuc caacggcugc gacuacgucu ccaacaaagg cgucgacaca     1320

gucuccgucg guaacacccu cuacugcgua aauaaacaag aaggccaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccucucgucu uccccuccga cgaauuugac     1440

gccucaauca gccaaguuaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaucc     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacca cgaacaucau gaucaccacc     1560

auaaucaucg uaauuaucgu aauacuccua ucccucauag caguaggccu ccuacucuac     1620

ugcaaagccc guuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  2968
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2968
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2969
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2969
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2970
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2970
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2971
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2971
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuauaugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaacaa aaucaagagc      480

gcccugcuga guacgaauaa agcugugguc ucccucucua acggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaauuacauu gacaaacaau ugcugccuau ccuaaacaag      600

caguccuguu caauuccaaa uaucgaaacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuaguguc aacgccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaauucuga gcuguugucc cucaucaacg auaugcccau uacgaacgac      780

caaaagaaac ugaugucaaa uaacguccag aucguucgcc agcagagcua caguaucaug      840

ugcauuauaa aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauc      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggc      960

uccaacauuu guuugacccg aacggaccgu gggugguacu gcgauaaugc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua acagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca auguggauau cuuuaacccc     1140

aaauaugacu guaagauaau gaccaguaaa acagauguaa gcuccucugu uauuacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa uaagaacagg     1260

gggaucauua agaccuucuc caauggaugc gacuauguca gcaacaaagg cguggacacu     1320

gucucugugg guaauacgcu uuacuguguu aacaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcauau cccaggucaa ugagaagauc aaccagucuc ucgcuuucau ucggaaaucg     1500

gacgaacugu uacacaaugu gaacgccggc aagagcacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua ucccucaucg cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2972
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2972
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2973
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2973
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuauuugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaacaa aaucaagucc      480

gcgcuucuga gcaccaauaa agccgucgug ucucucucca acggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaauuacauu gacaaacaac uccugccuau ccugaacaag      600

cagucuuguu ccauuccgaa uaucgaaacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuagcgug aacgcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaauuccga gcugcucagc cugaucaacg auaugccuau uaccaacgac      780

caaaagaaac uuauguccaa uaacgugcag aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaagga      960

uccaacaucu gucugacacg gaccgaccgc ggcugguacu gcgauaaugc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca acagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca augucgauau uuuuaacccc     1140

aaauaugacu guaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cugggagcga ucgugucuug cuacggcaag acaaaaugua cggccuccaa uaagaaccgg     1260

gggauuauca agaccuucag caauggaugc gacuauguuu cuaacaaagg cguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuaucauuaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauca gccaggugaa ugagaagauu aaccaguccc uggccuucau ccgcaaaucu     1500

gacgaacugc uccacaaugu gaacgcuggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucccugaucg ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2974
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2974
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuuaa agccaaugca      120

auaaccacaa uacuaacagc aguaacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aaucaacaug uucagcagua agcaaaggau accuaggagc cuuacgcaca      240

gguugguaca cuuccguaau aacaauagaa cucucaaaua uaaaagaaaa caaaugcaac      300

ggaaccgaug caaaaguaaa acuaauaaaa caagaauuag acaaauacaa aaacgcagua      360

acagaccuac aauuacuuau gcaaucaaca cccgcaacag gauccggcuc agcaaucugu      420

ucaggaguag caguaugcaa aguucuccac cuagaaggcg aaguaaacaa aauaaaauca      480

gcccuauuau cuaccaauaa agcaguagua ucacuaucaa auggaguauc uguccuaacc      540

uucaaaguac uugaccuaaa aaauuacauc gacaaacaau uacuaccaau acuuaacaaa      600

caaucauguu caauaccaaa cauugaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuauuagaaa uaacccgcga auuuucaguu aacgcaggag uaacaacacc aguauccaca      720

uacauguuaa caaauucaga acucuuauca cuuauaaacg acaugcccau aacaaacgac      780

caaaaaaaac ucaugucuaa caauguucaa auaguucgac aacaaucaua cuccauaaug      840

ugcauaauaa aagaagaagu ucuagcauau guuguacaac ucccacucua ugguguuaua      900

gacacaccau gcuggaaacu acauacaagc cccuuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacccg cacagacaga ggcugguauu gcgauaacgc agguucagua     1020

ucauucuuuc cacaagcaga aacuugcaaa guccaaucca auagagucuu cugcgacacu     1080

augaacucac ucacacuccc aucugaaguc aauuuaugua acgucgauau cuucaaccca     1140

aaauacgacu gcaaaauaau gaccucaaaa acagacguaa gcucaucagu cauaacuucu     1200

cuaggcgcaa ucgucucaug uuacggcaaa acaaaaugua ccgcaucaaa caaaaaucga     1260

gguauaauaa aaaccuuuuc uaacggcugc gacuacguau caaacaaagg aguagauacu     1320

guaagugucg gaaacacauu auacugcguc aacaaacaag aaggacaauc ccuauauguu     1380

aaaggcgaac cuaucauuaa uuucuacgac ccacucgucu uuccauccga cgaauuugac     1440

gcaucaauuu cccaaguaaa ugaaaaaaua aaccaauccc uugcauucau aagaaaauca     1500

gaugaacuau uacacaacgu aaacgcaggc aaaucaacaa caaauauaau gaucacaaca     1560

auaauaaucg uaauaauagu aauccuacuc ucacuaauag caguaggcuu acuauuauau     1620

ugcaaagcca gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2975
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2975
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uuauccuaaa agcgaacgcc      120

auaaccacaa uccuaacagc agucaccuuc uguuucgccu caggacaaaa caucaccgag      180

gaauuuuacc aauccacaug uagcgcuguc ucaaaaggcu accucggcgc ccuccgaacc      240

ggcugguaca cauccguaau aacgaucgaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg ccaaagucaa acuuaucaaa caagaacuag acaaauacaa aaacgccguc      360

accgaccucc agcuccucau gcaauccacc ccagcaacag gcuccggaag cgcaaucugc      420

ucaggcgucg ccguaugcaa aguacuccac cucgaaggag aagucaacaa aaucaaaucc      480

gcccuccuau ccacaaacaa agcaguuguc ucacucucca acgggguaag cguacugacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uccuuccaau ccucaacaaa      600

caaucaugcu cuauccccaa caucgaaacc guaaucgaau uucaacaaaa aaacaaccgc      660

cuacuugaaa ucacacgcga auuuagcguc aacgcaggag uaacaacacc cguguccaca      720

uauaugcuca cgaacagcga acuacuaucc cugauuaacg acaugcccau caccaacgac      780

caaaaaaaac uaaugagcaa caacguacaa aucguccgcc aacaaagcua cucuauaaug      840

ugcaucauca aggaagaagu ccuagccuac gucguccaau uaccacucua cggcgucauc      900

gacacacccu gcuggaaacu ccauacaucc ccccucugca ccaccaacac caaagaaggg      960

uccaacauau gccucacucg cacagaccgc ggcugguacu gcgacaacgc uggcagcguc     1020

agcuucuucc cccaggccga aaccugcaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucgc ucacccuccc cuccgagguc aaccucugca acgucgacau auucaacccc     1140

aaauacgacu gcaaaaucau gaccuccaaa accgacguca gcucaucagu caucacaucc     1200

cucggggcca ucgucuccug cuacggcaaa accaagugca ccgccucaaa caaaaaccgc     1260

ggcauuauca aaacauucuc caacggcugc gacuacgucu ccaacaaagg cgucgacaca     1320

gucuccgucg guaacacccu cuacugcgua aauaaacaag aaggccaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccucucgucu uccccuccga cgaauuugac     1440

gccucaauca gccaaguuaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaucc     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacca cgaacaucau gaucaccacc     1560

auaaucaucg uaauuaucgu aauacuccua ucccucauag caguaggccu ccuacucuac     1620

ugcaaagccc guuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  2976
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2976
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2977
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2977
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2978
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2978
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2979
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2979
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2980
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2980
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2981
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2981
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2982
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2982
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuuaaagc caaugcaaua accacaauac      120

uaacagcagu aacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

caacauguuc agcaguaagc aaaggauacc uaggagccuu acgcacaggu ugguacacuu      240

ccguaauaac aauagaacuc ucaaauauaa aagaaaacaa augcaacgga accgaugcaa      300

aaguaaaacu aauaaaacaa gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau      360

uacuuaugca aucaacaccc gcaacaggau ccggcucagc aaucuguuca ggaguagcag      420

uaugcaaagu ucuccaccua gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua      480

ccaauaaagc aguaguauca cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug      540

accuaaaaaa uuacaucgac aaacaauuac uaccaauacu uaacaaacaa ucauguucaa      600

uaccaaacau ugaaacagua auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa      660

cccgcgaauu uucaguuaac gcaggaguaa caacaccagu auccacauac auguuaacaa      720

auucagaacu cuuaucacuu auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa uguucaaaua guucgacaac aaucauacuc cauaaugugc auaauaaaag      840

aagaaguucu agcauauguu guacaacucc cacucuaugg uguuauagac acaccaugcu      900

ggaaacuaca uacaagcccc uuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacccgcac agacagaggc ugguauugcg auaacgcagg uucaguauca uucuuuccac     1020

aagcagaaac uugcaaaguc caauccaaua gagucuucug cgacacuaug aacucacuca     1080

cacucccauc ugaagucaau uuauguaacg ucgauaucuu caacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguaagcu caucagucau aacuucucua ggcgcaaucg     1200

ucucauguua cggcaaaaca aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa     1260

ccuuuucuaa cggcugcgac uacguaucaa acaaaggagu agauacugua agugucggaa     1320

acacauuaua cugcgucaac aaacaagaag gacaaucccu auauguuaaa ggcgaaccua     1380

ucauuaauuu cuacgaccca cucgucuuuc cauccgacga auuugacgca ucaauuuccc     1440

aaguaaauga aaaaauaaac caaucccuug cauucauaag aaaaucagau gaacuauuac     1500

acaacguaaa cgcaggcaaa ucaacaacaa auauaaugau cacaacaaua auaaucguaa     1560

uaauaguaau ccuacucuca cuaauagcag uaggcuuacu auuauauugc aaagccagau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2983
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2983
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuua uccuaaaagc gaacgccaua accacaaucc      120

uaacagcagu caccuucugu uucgccucag gacaaaacau caccgaggaa uuuuaccaau      180

ccacauguag cgcugucuca aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau      240

ccguaauaac gaucgaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcca      300

aagucaaacu uaucaaacaa gaacuagaca aauacaaaaa cgccgucacc gaccuccagc      360

uccucaugca auccacccca gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg      420

uaugcaaagu acuccaccuc gaaggagaag ucaacaaaau caaauccgcc cuccuaucca      480

caaacaaagc aguugucuca cucuccaacg ggguaagcgu acugaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacucc uuccaauccu caacaaacaa ucaugcucua      600

uccccaacau cgaaaccgua aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca      660

cacgcgaauu uagcgucaac gcaggaguaa caacacccgu guccacauau augcucacga      720

acagcgaacu acuaucccug auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa      780

ugagcaacaa cguacaaauc guccgccaac aaagcuacuc uauaaugugc aucaucaagg      840

aagaaguccu agccuacguc guccaauuac cacucuacgg cgucaucgac acacccugcu      900

ggaaacucca uacauccccc cucugcacca ccaacaccaa agaagggucc aacauaugcc      960

ucacucgcac agaccgcggc ugguacugcg acaacgcugg cagcgucagc uucuuccccc     1020

aggccgaaac cugcaaaguc caauccaaca gagucuucug cgacaccaug aacucgcuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacauauu caaccccaaa uacgacugca     1140

aaaucaugac cuccaaaacc gacgucagcu caucagucau cacaucccuc ggggccaucg     1200

ucuccugcua cggcaaaacc aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa     1260

cauucuccaa cggcugcgac uacgucucca acaaaggcgu cgacacaguc uccgucggua     1320

acacccucua cugcguaaau aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccu cucgucuucc ccuccgacga auuugacgcc ucaaucagcc     1440

aaguuaacga aaaaaucaac caaucacucg ccuucauccg caaauccgac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuaccacga acaucaugau caccaccaua aucaucguaa     1560

uuaucguaau acuccuaucc cucauagcag uaggccuccu acucuacugc aaagcccguu     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  2984
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2984
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2985
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2985
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2986
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2986
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2987
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2987
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uauauguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaacaaaau caagagcgcc cugcugagua      480

cgaauaaagc uguggucucc cucucuaacg gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa uuacauugac aaacaauugc ugccuauccu aaacaagcag uccuguucaa      600

uuccaaauau cgaaaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uagugucaac gccggaguga cuaccccggu gagcacauau augcuuacca      720

auucugagcu guugucccuc aucaacgaua ugcccauuac gaacgaccaa aagaaacuga      780

ugucaaauaa cguccagauc guucgccagc agagcuacag uaucaugugc auuauaaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucaucgau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaauacaaa ggaaggcucc aacauuuguu      960

ugacccgaac ggaccguggg ugguacugcg auaaugcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaca gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaaug uggauaucuu uaaccccaaa uaugacugua     1140

agauaaugac caguaaaaca gauguaagcu ccucuguuau uacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaauaa gaacaggggg aucauuaaga     1260

ccuucuccaa uggaugcgac uaugucagca acaaaggcgu ggacacuguc ucugugggua     1320

auacgcuuua cuguguuaac aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcauauccc     1440

aggucaauga gaagaucaac cagucucucg cuuucauucg gaaaucggac gaacuguuac     1500

acaaugugaa cgccggcaag agcacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaucc cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2988
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2988
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2989
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2989
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uauuuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaacaaaau caaguccgcg cuucugagca      480

ccaauaaagc cgucgugucu cucuccaacg gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa uuacauugac aaacaacucc ugccuauccu gaacaagcag ucuuguucca      600

uuccgaauau cgaaaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uagcgugaac gcuggcguca caacccccgu uucuacauau augcuuacca      720

auuccgagcu gcucagccug aucaacgaua ugccuauuac caacgaccaa aagaaacuua      780

uguccaauaa cgugcagauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaauaccaa ggaaggaucc aacaucuguc      960

ugacacggac cgaccgcggc ugguacugcg auaaugcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaca gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaaug ucgauauuuu uaaccccaaa uaugacugua     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccug ggagcgaucg     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaauaa gaaccggggg auuaucaaga     1260

ccuucagcaa uggaugcgac uauguuucua acaaaggcgu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

ucauuaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuaucagcc     1440

aggugaauga gaagauuaac cagucccugg ccuucauccg caaaucugac gaacugcucc     1500

acaaugugaa cgcuggcaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucc cugaucgccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2990
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2990
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuuaaagc caaugcaaua accacaauac      120

uaacagcagu aacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

caacauguuc agcaguaagc aaaggauacc uaggagccuu acgcacaggu ugguacacuu      240

ccguaauaac aauagaacuc ucaaauauaa aagaaaacaa augcaacgga accgaugcaa      300

aaguaaaacu aauaaaacaa gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau      360

uacuuaugca aucaacaccc gcaacaggau ccggcucagc aaucuguuca ggaguagcag      420

uaugcaaagu ucuccaccua gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua      480

ccaauaaagc aguaguauca cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug      540

accuaaaaaa uuacaucgac aaacaauuac uaccaauacu uaacaaacaa ucauguucaa      600

uaccaaacau ugaaacagua auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa      660

cccgcgaauu uucaguuaac gcaggaguaa caacaccagu auccacauac auguuaacaa      720

auucagaacu cuuaucacuu auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa uguucaaaua guucgacaac aaucauacuc cauaaugugc auaauaaaag      840

aagaaguucu agcauauguu guacaacucc cacucuaugg uguuauagac acaccaugcu      900

ggaaacuaca uacaagcccc uuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacccgcac agacagaggc ugguauugcg auaacgcagg uucaguauca uucuuuccac     1020

aagcagaaac uugcaaaguc caauccaaua gagucuucug cgacacuaug aacucacuca     1080

cacucccauc ugaagucaau uuauguaacg ucgauaucuu caacccaaaa uacgacugca     1140

aaauaaugac cucaaaaaca gacguaagcu caucagucau aacuucucua ggcgcaaucg     1200

ucucauguua cggcaaaaca aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa     1260

ccuuuucuaa cggcugcgac uacguaucaa acaaaggagu agauacugua agugucggaa     1320

acacauuaua cugcgucaac aaacaagaag gacaaucccu auauguuaaa ggcgaaccua     1380

ucauuaauuu cuacgaccca cucgucuuuc cauccgacga auuugacgca ucaauuuccc     1440

aaguaaauga aaaaauaaac caaucccuug cauucauaag aaaaucagau gaacuauuac     1500

acaacguaaa cgcaggcaaa ucaacaacaa auauaaugau cacaacaaua auaaucguaa     1560

uaauaguaau ccuacucuca cuaauagcag uaggcuuacu auuauauugc aaagccagau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2991
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2991
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuua uccuaaaagc gaacgccaua accacaaucc      120

uaacagcagu caccuucugu uucgccucag gacaaaacau caccgaggaa uuuuaccaau      180

ccacauguag cgcugucuca aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau      240

ccguaauaac gaucgaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcca      300

aagucaaacu uaucaaacaa gaacuagaca aauacaaaaa cgccgucacc gaccuccagc      360

uccucaugca auccacccca gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg      420

uaugcaaagu acuccaccuc gaaggagaag ucaacaaaau caaauccgcc cuccuaucca      480

caaacaaagc aguugucuca cucuccaacg ggguaagcgu acugaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacucc uuccaauccu caacaaacaa ucaugcucua      600

uccccaacau cgaaaccgua aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca      660

cacgcgaauu uagcgucaac gcaggaguaa caacacccgu guccacauau augcucacga      720

acagcgaacu acuaucccug auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa      780

ugagcaacaa cguacaaauc guccgccaac aaagcuacuc uauaaugugc aucaucaagg      840

aagaaguccu agccuacguc guccaauuac cacucuacgg cgucaucgac acacccugcu      900

ggaaacucca uacauccccc cucugcacca ccaacaccaa agaagggucc aacauaugcc      960

ucacucgcac agaccgcggc ugguacugcg acaacgcugg cagcgucagc uucuuccccc     1020

aggccgaaac cugcaaaguc caauccaaca gagucuucug cgacaccaug aacucgcuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacauauu caaccccaaa uacgacugca     1140

aaaucaugac cuccaaaacc gacgucagcu caucagucau cacaucccuc ggggccaucg     1200

ucuccugcua cggcaaaacc aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa     1260

cauucuccaa cggcugcgac uacgucucca acaaaggcgu cgacacaguc uccgucggua     1320

acacccucua cugcguaaau aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccu cucgucuucc ccuccgacga auuugacgcc ucaaucagcc     1440

aaguuaacga aaaaaucaac caaucacucg ccuucauccg caaauccgac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuaccacga acaucaugau caccaccaua aucaucguaa     1560

uuaucguaau acuccuaucc cucauagcag uaggccuccu acucuacugc aaagcccguu     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  2992
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2992
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2993
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  2993
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2994
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  2994
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2995
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  2995
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2996
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  2996
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2997
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  2997
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2998
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  2998
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuuaaa gccaaugcaa uaaccacaau acuaacagca      120

guaacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca aucaacaugu      180

ucagcaguaa gcaaaggaua ccuaggagcc uuacgcacag guugguacac uuccguaaua      240

acaauagaac ucucaaauau aaaagaaaac aaaugcaacg gaaccgaugc aaaaguaaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgcaguaa cagaccuaca auuacuuaug      360

caaucaacac ccgcaacagg auccggcuca gcaaucuguu caggaguagc aguaugcaaa      420

guucuccacc uagaaggcga aguaaacaaa auaaaaucag cccuauuauc uaccaauaaa      480

gcaguaguau cacuaucaaa uggaguaucu guccuaaccu ucaaaguacu ugaccuaaaa      540

aauuacaucg acaaacaauu acuaccaaua cuuaacaaac aaucauguuc aauaccaaac      600

auugaaacag uaauagaauu ucaacaaaaa aauaacagau uauuagaaau aacccgcgaa      660

uuuucaguua acgcaggagu aacaacacca guauccacau acauguuaac aaauucagaa      720

cucuuaucac uuauaaacga caugcccaua acaaacgacc aaaaaaaacu caugucuaac      780

aauguucaaa uaguucgaca acaaucauac uccauaaugu gcauaauaaa agaagaaguu      840

cuagcauaug uuguacaacu cccacucuau gguguuauag acacaccaug cuggaaacua      900

cauacaagcc ccuuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacccgc      960

acagacagag gcugguauug cgauaacgca gguucaguau cauucuuucc acaagcagaa     1020

acuugcaaag uccaauccaa uagagucuuc ugcgacacua ugaacucacu cacacuccca     1080

ucugaaguca auuuauguaa cgucgauauc uucaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguaag cucaucaguc auaacuucuc uaggcgcaau cgucucaugu     1200

uacggcaaaa caaaauguac cgcaucaaac aaaaaucgag guauaauaaa aaccuuuucu     1260

aacggcugcg acuacguauc aaacaaagga guagauacug uaagugucgg aaacacauua     1320

uacugcguca acaaacaaga aggacaaucc cuauauguua aaggcgaacc uaucauuaau     1380

uucuacgacc cacucgucuu uccauccgac gaauuugacg caucaauuuc ccaaguaaau     1440

gaaaaaauaa accaaucccu ugcauucaua agaaaaucag augaacuauu acacaacgua     1500

aacgcaggca aaucaacaac aaauauaaug aucacaacaa uaauaaucgu aauaauagua     1560

auccuacucu cacuaauagc aguaggcuua cuauuauauu gcaaagccag auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  2999
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  2999
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu uauccuaaaa gcgaacgcca uaaccacaau ccuaacagca      120

gucaccuucu guuucgccuc aggacaaaac aucaccgagg aauuuuacca auccacaugu      180

agcgcugucu caaaaggcua ccucggcgcc cuccgaaccg gcugguacac auccguaaua      240

acgaucgaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc caaagucaaa      300

cuuaucaaac aagaacuaga caaauacaaa aacgccguca ccgaccucca gcuccucaug      360

caauccaccc cagcaacagg cuccggaagc gcaaucugcu caggcgucgc cguaugcaaa      420

guacuccacc ucgaaggaga agucaacaaa aucaaauccg cccuccuauc cacaaacaaa      480

gcaguugucu cacucuccaa cgggguaagc guacugaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu ccuuccaauc cucaacaaac aaucaugcuc uauccccaac      600

aucgaaaccg uaaucgaauu ucaacaaaaa aacaaccgcc uacuugaaau cacacgcgaa      660

uuuagcguca acgcaggagu aacaacaccc guguccacau auaugcucac gaacagcgaa      720

cuacuauccc ugauuaacga caugcccauc accaacgacc aaaaaaaacu aaugagcaac      780

aacguacaaa ucguccgcca acaaagcuac ucuauaaugu gcaucaucaa ggaagaaguc      840

cuagccuacg ucguccaauu accacucuac ggcgucaucg acacacccug cuggaaacuc      900

cauacauccc cccucugcac caccaacacc aaagaagggu ccaacauaug ccucacucgc      960

acagaccgcg gcugguacug cgacaacgcu ggcagcguca gcuucuuccc ccaggccgaa     1020

accugcaaag uccaauccaa cagagucuuc ugcgacacca ugaacucgcu cacccucccc     1080

uccgagguca accucugcaa cgucgacaua uucaacccca aauacgacug caaaaucaug     1140

accuccaaaa ccgacgucag cucaucaguc aucacauccc ucggggccau cgucuccugc     1200

uacggcaaaa ccaagugcac cgccucaaac aaaaaccgcg gcauuaucaa aacauucucc     1260

aacggcugcg acuacgucuc caacaaaggc gucgacacag ucuccgucgg uaacacccuc     1320

uacugcguaa auaaacaaga aggccaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cucucgucuu ccccuccgac gaauuugacg ccucaaucag ccaaguuaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaauccg acgaacuccu ccacaacguu     1500

aacgccggca aaucuaccac gaacaucaug aucaccacca uaaucaucgu aauuaucgua     1560

auacuccuau cccucauagc aguaggccuc cuacucuacu gcaaagcccg uuaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3000
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3000
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3001
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3001
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3002
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3002
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3003
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3003
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuauauguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaacaaa aucaagagcg cccugcugag uacgaauaaa      480

gcuguggucu cccucucuaa cggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aauuacauug acaaacaauu gcugccuauc cuaaacaagc aguccuguuc aauuccaaau      600

aucgaaaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuaguguca acgccggagu gacuaccccg gugagcacau auaugcuuac caauucugag      720

cuguuguccc ucaucaacga uaugcccauu acgaacgacc aaaagaaacu gaugucaaau      780

aacguccaga ucguucgcca gcagagcuac aguaucaugu gcauuauaaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucaucg auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaauaca aaggaaggcu ccaacauuug uuugacccga      960

acggaccgug ggugguacug cgauaaugca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa cagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa uguggauauc uuuaacccca aauaugacug uaagauaaug     1140

accaguaaaa cagauguaag cuccucuguu auuacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaau aagaacaggg ggaucauuaa gaccuucucc     1260

aauggaugcg acuaugucag caacaaaggc guggacacug ucucuguggg uaauacgcuu     1320

uacuguguua acaagcaaga ggggcaguca cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcauauc ccaggucaau     1440

gagaagauca accagucucu cgcuuucauu cggaaaucgg acgaacuguu acacaaugug     1500

aacgccggca agagcacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuau cccucaucgc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3004
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3004
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3005
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3005
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuauuugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaacaaa aucaaguccg cgcuucugag caccaauaaa      480

gccgucgugu cucucuccaa cggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aauuacauug acaaacaacu ccugccuauc cugaacaagc agucuuguuc cauuccgaau      600

aucgaaaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuagcguga acgcuggcgu cacaaccccc guuucuacau auaugcuuac caauuccgag      720

cugcucagcc ugaucaacga uaugccuauu accaacgacc aaaagaaacu uauguccaau      780

aacgugcaga ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaauacc aaggaaggau ccaacaucug ucugacacgg      960

accgaccgcg gcugguacug cgauaaugcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa ugucgauauu uuuaacccca aauaugacug uaagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ugggagcgau cgugucuugc     1200

uacggcaaga caaaauguac ggccuccaau aagaaccggg ggauuaucaa gaccuucagc     1260

aauggaugcg acuauguuuc uaacaaaggc guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga ggggcagagc cuguauguga aaggagagcc uaucauuaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuaucag ccaggugaau     1440

gagaagauua accagucccu ggccuucauc cgcaaaucug acgaacugcu ccacaaugug     1500

aacgcuggca agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cccugaucgc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3006
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3006
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuuaaa gccaaugcaa uaaccacaau acuaacagca      120

guaacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca aucaacaugu      180

ucagcaguaa gcaaaggaua ccuaggagcc uuacgcacag guugguacac uuccguaaua      240

acaauagaac ucucaaauau aaaagaaaac aaaugcaacg gaaccgaugc aaaaguaaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgcaguaa cagaccuaca auuacuuaug      360

caaucaacac ccgcaacagg auccggcuca gcaaucuguu caggaguagc aguaugcaaa      420

guucuccacc uagaaggcga aguaaacaaa auaaaaucag cccuauuauc uaccaauaaa      480

gcaguaguau cacuaucaaa uggaguaucu guccuaaccu ucaaaguacu ugaccuaaaa      540

aauuacaucg acaaacaauu acuaccaaua cuuaacaaac aaucauguuc aauaccaaac      600

auugaaacag uaauagaauu ucaacaaaaa aauaacagau uauuagaaau aacccgcgaa      660

uuuucaguua acgcaggagu aacaacacca guauccacau acauguuaac aaauucagaa      720

cucuuaucac uuauaaacga caugcccaua acaaacgacc aaaaaaaacu caugucuaac      780

aauguucaaa uaguucgaca acaaucauac uccauaaugu gcauaauaaa agaagaaguu      840

cuagcauaug uuguacaacu cccacucuau gguguuauag acacaccaug cuggaaacua      900

cauacaagcc ccuuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacccgc      960

acagacagag gcugguauug cgauaacgca gguucaguau cauucuuucc acaagcagaa     1020

acuugcaaag uccaauccaa uagagucuuc ugcgacacua ugaacucacu cacacuccca     1080

ucugaaguca auuuauguaa cgucgauauc uucaacccaa aauacgacug caaaauaaug     1140

accucaaaaa cagacguaag cucaucaguc auaacuucuc uaggcgcaau cgucucaugu     1200

uacggcaaaa caaaauguac cgcaucaaac aaaaaucgag guauaauaaa aaccuuuucu     1260

aacggcugcg acuacguauc aaacaaagga guagauacug uaagugucgg aaacacauua     1320

uacugcguca acaaacaaga aggacaaucc cuauauguua aaggcgaacc uaucauuaau     1380

uucuacgacc cacucgucuu uccauccgac gaauuugacg caucaauuuc ccaaguaaau     1440

gaaaaaauaa accaaucccu ugcauucaua agaaaaucag augaacuauu acacaacgua     1500

aacgcaggca aaucaacaac aaauauaaug aucacaacaa uaauaaucgu aauaauagua     1560

auccuacucu cacuaauagc aguaggcuua cuauuauauu gcaaagccag auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3007
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3007
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu uauccuaaaa gcgaacgcca uaaccacaau ccuaacagca      120

gucaccuucu guuucgccuc aggacaaaac aucaccgagg aauuuuacca auccacaugu      180

agcgcugucu caaaaggcua ccucggcgcc cuccgaaccg gcugguacac auccguaaua      240

acgaucgaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc caaagucaaa      300

cuuaucaaac aagaacuaga caaauacaaa aacgccguca ccgaccucca gcuccucaug      360

caauccaccc cagcaacagg cuccggaagc gcaaucugcu caggcgucgc cguaugcaaa      420

guacuccacc ucgaaggaga agucaacaaa aucaaauccg cccuccuauc cacaaacaaa      480

gcaguugucu cacucuccaa cgggguaagc guacugaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu ccuuccaauc cucaacaaac aaucaugcuc uauccccaac      600

aucgaaaccg uaaucgaauu ucaacaaaaa aacaaccgcc uacuugaaau cacacgcgaa      660

uuuagcguca acgcaggagu aacaacaccc guguccacau auaugcucac gaacagcgaa      720

cuacuauccc ugauuaacga caugcccauc accaacgacc aaaaaaaacu aaugagcaac      780

aacguacaaa ucguccgcca acaaagcuac ucuauaaugu gcaucaucaa ggaagaaguc      840

cuagccuacg ucguccaauu accacucuac ggcgucaucg acacacccug cuggaaacuc      900

cauacauccc cccucugcac caccaacacc aaagaagggu ccaacauaug ccucacucgc      960

acagaccgcg gcugguacug cgacaacgcu ggcagcguca gcuucuuccc ccaggccgaa     1020

accugcaaag uccaauccaa cagagucuuc ugcgacacca ugaacucgcu cacccucccc     1080

uccgagguca accucugcaa cgucgacaua uucaacccca aauacgacug caaaaucaug     1140

accuccaaaa ccgacgucag cucaucaguc aucacauccc ucggggccau cgucuccugc     1200

uacggcaaaa ccaagugcac cgccucaaac aaaaaccgcg gcauuaucaa aacauucucc     1260

aacggcugcg acuacgucuc caacaaaggc gucgacacag ucuccgucgg uaacacccuc     1320

uacugcguaa auaaacaaga aggccaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cucucgucuu ccccuccgac gaauuugacg ccucaaucag ccaaguuaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaauccg acgaacuccu ccacaacguu     1500

aacgccggca aaucuaccac gaacaucaug aucaccacca uaaucaucgu aauuaucgua     1560

auacuccuau cccucauagc aguaggccuc cuacucuacu gcaaagcccg uuaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3008
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3008
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3009
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3009
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3010
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3010
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3011
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3011
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3012
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3012
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3013
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3013
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3014
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3014
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuuaaagcc      120

aaugcaauaa ccacaauacu aacagcagua acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc aacauguuca gcaguaagca aaggauaccu aggagccuua      240

cgcacagguu gguacacuuc cguaauaaca auagaacucu caaauauaaa agaaaacaaa      300

ugcaacggaa ccgaugcaaa aguaaaacua auaaaacaag aauuagacaa auacaaaaac      360

gcaguaacag accuacaauu acuuaugcaa ucaacacccg caacaggauc cggcucagca      420

aucuguucag gaguagcagu augcaaaguu cuccaccuag aaggcgaagu aaacaaaaua      480

aaaucagccc uauuaucuac caauaaagca guaguaucac uaucaaaugg aguaucuguc      540

cuaaccuuca aaguacuuga ccuaaaaaau uacaucgaca aacaauuacu accaauacuu      600

aacaaacaau cauguucaau accaaacauu gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuau uagaaauaac ccgcgaauuu ucaguuaacg caggaguaac aacaccagua      720

uccacauaca uguuaacaaa uucagaacuc uuaucacuua uaaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau gucuaacaau guucaaauag uucgacaaca aucauacucc      840

auaaugugca uaauaaaaga agaaguucua gcauauguug uacaacuccc acucuauggu      900

guuauagaca caccaugcug gaaacuacau acaagccccu uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacccgcaca gacagaggcu gguauugcga uaacgcaggu     1020

ucaguaucau ucuuuccaca agcagaaacu ugcaaagucc aauccaauag agucuucugc     1080

gacacuauga acucacucac acucccaucu gaagucaauu uauguaacgu cgauaucuuc     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguaagcuc aucagucaua     1200

acuucucuag gcgcaaucgu cucauguuac ggcaaaacaa aauguaccgc aucaaacaaa     1260

aaucgaggua uaauaaaaac cuuuucuaac ggcugcgacu acguaucaaa caaaggagua     1320

gauacuguaa gugucggaaa cacauuauac ugcgucaaca aacaagaagg acaaucccua     1380

uauguuaaag gcgaaccuau cauuaauuuc uacgacccac ucgucuuucc auccgacgaa     1440

uuugacgcau caauuuccca aguaaaugaa aaaauaaacc aaucccuugc auucauaaga     1500

aaaucagaug aacuauuaca caacguaaac gcaggcaaau caacaacaaa uauaaugauc     1560

acaacaauaa uaaucguaau aauaguaauc cuacucucac uaauagcagu aggcuuacua     1620

uuauauugca aagccagaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3015
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3015
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuuau ccuaaaagcg      120

aacgccauaa ccacaauccu aacagcaguc accuucuguu ucgccucagg acaaaacauc      180

accgaggaau uuuaccaauc cacauguagc gcugucucaa aaggcuaccu cggcgcccuc      240

cgaaccggcu gguacacauc cguaauaacg aucgaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgccaa agucaaacuu aucaaacaag aacuagacaa auacaaaaac      360

gccgucaccg accuccagcu ccucaugcaa uccaccccag caacaggcuc cggaagcgca      420

aucugcucag gcgucgccgu augcaaagua cuccaccucg aaggagaagu caacaaaauc      480

aaauccgccc uccuauccac aaacaaagca guugucucac ucuccaacgg gguaagcgua      540

cugaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuccu uccaauccuc      600

aacaaacaau caugcucuau ccccaacauc gaaaccguaa ucgaauuuca acaaaaaaac      660

aaccgccuac uugaaaucac acgcgaauuu agcgucaacg caggaguaac aacacccgug      720

uccacauaua ugcucacgaa cagcgaacua cuaucccuga uuaacgacau gcccaucacc      780

aacgaccaaa aaaaacuaau gagcaacaac guacaaaucg uccgccaaca aagcuacucu      840

auaaugugca ucaucaagga agaaguccua gccuacgucg uccaauuacc acucuacggc      900

gucaucgaca cacccugcug gaaacuccau acaucccccc ucugcaccac caacaccaaa      960

gaagggucca acauaugccu cacucgcaca gaccgcggcu gguacugcga caacgcuggc     1020

agcgucagcu ucuuccccca ggccgaaacc ugcaaagucc aauccaacag agucuucugc     1080

gacaccauga acucgcucac ccuccccucc gaggucaacc ucugcaacgu cgacauauuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaaaaccg acgucagcuc aucagucauc     1200

acaucccucg gggccaucgu cuccugcuac ggcaaaacca agugcaccgc cucaaacaaa     1260

aaccgcggca uuaucaaaac auucuccaac ggcugcgacu acgucuccaa caaaggcguc     1320

gacacagucu ccgucgguaa cacccucuac ugcguaaaua aacaagaagg ccaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgacccuc ucgucuuccc cuccgacgaa     1440

uuugacgccu caaucagcca aguuaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaauccgacg aacuccucca caacguuaac gccggcaaau cuaccacgaa caucaugauc     1560

accaccauaa ucaucguaau uaucguaaua cuccuauccc ucauagcagu aggccuccua     1620

cucuacugca aagcccguua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3016
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3016
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3017
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3017
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3018
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3018
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3019
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3019
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

auauguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaacaaaauc      480

aagagcgccc ugcugaguac gaauaaagcu guggucuccc ucucuaacgg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaau uacauugaca aacaauugcu gccuauccua      600

aacaagcagu ccuguucaau uccaaauauc gaaaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu agugucaacg ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa uucugagcug uugucccuca ucaacgauau gcccauuacg      780

aacgaccaaa agaaacugau gucaaauaac guccagaucg uucgccagca gagcuacagu      840

aucaugugca uuauaaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucaucgaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaauacaaag      960

gaaggcucca acauuuguuu gacccgaacg gaccgugggu gguacugcga uaaugcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaacag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaaugu ggauaucuuu     1140

aaccccaaau augacuguaa gauaaugacc aguaaaacag auguaagcuc cucuguuauu     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaauaag     1260

aacaggggga ucauuaagac cuucuccaau ggaugcgacu augucagcaa caaaggcgug     1320

gacacugucu cuguggguaa uacgcuuuac uguguuaaca agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau cauuaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcauauccca ggucaaugag aagaucaacc agucucucgc uuucauucgg     1500

aaaucggacg aacuguuaca caaugugaac gccggcaaga gcacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuauccc ucaucgcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3020
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3020
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3021
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3021
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

auuuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaacaaaauc      480

aaguccgcgc uucugagcac caauaaagcc gucgugucuc ucuccaacgg cguuagcgug      540

cugacauuua agguccuuga ucugaagaau uacauugaca aacaacuccu gccuauccug      600

aacaagcagu cuuguuccau uccgaauauc gaaaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa uuccgagcug cucagccuga ucaacgauau gccuauuacc      780

aacgaccaaa agaaacuuau guccaauaac gugcagaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaauaccaag      960

gaaggaucca acaucugucu gacacggacc gaccgcggcu gguacugcga uaaugcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaacag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaaugu cgauauuuuu     1140

aaccccaaau augacuguaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccugg gagcgaucgu gucuugcuac ggcaagacaa aauguacggc cuccaauaag     1260

aaccggggga uuaucaagac cuucagcaau ggaugcgacu auguuucuaa caaaggcgug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau cauuaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuaucagcca ggugaaugag aagauuaacc agucccuggc cuucauccgc     1500

aaaucugacg aacugcucca caaugugaac gcuggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuuccc ugaucgccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3022
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3022
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuuaaagcc      120

aaugcaauaa ccacaauacu aacagcagua acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc aacauguuca gcaguaagca aaggauaccu aggagccuua      240

cgcacagguu gguacacuuc cguaauaaca auagaacucu caaauauaaa agaaaacaaa      300

ugcaacggaa ccgaugcaaa aguaaaacua auaaaacaag aauuagacaa auacaaaaac      360

gcaguaacag accuacaauu acuuaugcaa ucaacacccg caacaggauc cggcucagca      420

aucuguucag gaguagcagu augcaaaguu cuccaccuag aaggcgaagu aaacaaaaua      480

aaaucagccc uauuaucuac caauaaagca guaguaucac uaucaaaugg aguaucuguc      540

cuaaccuuca aaguacuuga ccuaaaaaau uacaucgaca aacaauuacu accaauacuu      600

aacaaacaau cauguucaau accaaacauu gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuau uagaaauaac ccgcgaauuu ucaguuaacg caggaguaac aacaccagua      720

uccacauaca uguuaacaaa uucagaacuc uuaucacuua uaaacgacau gcccauaaca      780

aacgaccaaa aaaaacucau gucuaacaau guucaaauag uucgacaaca aucauacucc      840

auaaugugca uaauaaaaga agaaguucua gcauauguug uacaacuccc acucuauggu      900

guuauagaca caccaugcug gaaacuacau acaagccccu uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacccgcaca gacagaggcu gguauugcga uaacgcaggu     1020

ucaguaucau ucuuuccaca agcagaaacu ugcaaagucc aauccaauag agucuucugc     1080

gacacuauga acucacucac acucccaucu gaagucaauu uauguaacgu cgauaucuuc     1140

aacccaaaau acgacugcaa aauaaugacc ucaaaaacag acguaagcuc aucagucaua     1200

acuucucuag gcgcaaucgu cucauguuac ggcaaaacaa aauguaccgc aucaaacaaa     1260

aaucgaggua uaauaaaaac cuuuucuaac ggcugcgacu acguaucaaa caaaggagua     1320

gauacuguaa gugucggaaa cacauuauac ugcgucaaca aacaagaagg acaaucccua     1380

uauguuaaag gcgaaccuau cauuaauuuc uacgacccac ucgucuuucc auccgacgaa     1440

uuugacgcau caauuuccca aguaaaugaa aaaauaaacc aaucccuugc auucauaaga     1500

aaaucagaug aacuauuaca caacguaaac gcaggcaaau caacaacaaa uauaaugauc     1560

acaacaauaa uaaucguaau aauaguaauc cuacucucac uaauagcagu aggcuuacua     1620

uuauauugca aagccagaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3023
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3023
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuuau ccuaaaagcg      120

aacgccauaa ccacaauccu aacagcaguc accuucuguu ucgccucagg acaaaacauc      180

accgaggaau uuuaccaauc cacauguagc gcugucucaa aaggcuaccu cggcgcccuc      240

cgaaccggcu gguacacauc cguaauaacg aucgaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgccaa agucaaacuu aucaaacaag aacuagacaa auacaaaaac      360

gccgucaccg accuccagcu ccucaugcaa uccaccccag caacaggcuc cggaagcgca      420

aucugcucag gcgucgccgu augcaaagua cuccaccucg aaggagaagu caacaaaauc      480

aaauccgccc uccuauccac aaacaaagca guugucucac ucuccaacgg gguaagcgua      540

cugaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuccu uccaauccuc      600

aacaaacaau caugcucuau ccccaacauc gaaaccguaa ucgaauuuca acaaaaaaac      660

aaccgccuac uugaaaucac acgcgaauuu agcgucaacg caggaguaac aacacccgug      720

uccacauaua ugcucacgaa cagcgaacua cuaucccuga uuaacgacau gcccaucacc      780

aacgaccaaa aaaaacuaau gagcaacaac guacaaaucg uccgccaaca aagcuacucu      840

auaaugugca ucaucaagga agaaguccua gccuacgucg uccaauuacc acucuacggc      900

gucaucgaca cacccugcug gaaacuccau acaucccccc ucugcaccac caacaccaaa      960

gaagggucca acauaugccu cacucgcaca gaccgcggcu gguacugcga caacgcuggc     1020

agcgucagcu ucuuccccca ggccgaaacc ugcaaagucc aauccaacag agucuucugc     1080

gacaccauga acucgcucac ccuccccucc gaggucaacc ucugcaacgu cgacauauuc     1140

aaccccaaau acgacugcaa aaucaugacc uccaaaaccg acgucagcuc aucagucauc     1200

acaucccucg gggccaucgu cuccugcuac ggcaaaacca agugcaccgc cucaaacaaa     1260

aaccgcggca uuaucaaaac auucuccaac ggcugcgacu acgucuccaa caaaggcguc     1320

gacacagucu ccgucgguaa cacccucuac ugcguaaaua aacaagaagg ccaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgacccuc ucgucuuccc cuccgacgaa     1440

uuugacgccu caaucagcca aguuaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaauccgacg aacuccucca caacguuaac gccggcaaau cuaccacgaa caucaugauc     1560

accaccauaa ucaucguaau uaucguaaua cuccuauccc ucauagcagu aggccuccua     1620

cucuacugca aagcccguua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3024
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3024
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3025
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3025
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3026
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3026
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3027
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3027
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug      540

gucucccucu cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      600

auugacaaac aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu      720

gucaacgccg gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      780

ucccucauca acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc      840

cagaucguuc gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac     1020

cguggguggu acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu     1200

aaaacagaug uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga     1320

ugcgacuaug ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu     1380

guuaacaagc aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag     1500

aucaaccagu cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc     1560

ggcaagagca caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaucccuca ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3028
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3028
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3029
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3029
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc      540

gugucucucu ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      600

auugacaaac aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      720

gugaacgcug gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      780

agccugauca acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug      840

cagaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac     1020

cgcggcuggu acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc     1260

aagacaaaau guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga     1320

ugcgacuaug uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag     1500

auuaaccagu cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu     1560

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucccuga ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3030
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3030
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu uaaagccaau gcaauaacca caauacuaac agcaguaaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaaucaac auguucagca      240

guaagcaaag gauaccuagg agccuuacgc acagguuggu acacuuccgu aauaacaaua      300

gaacucucaa auauaaaaga aaacaaaugc aacggaaccg augcaaaagu aaaacuaaua      360

aaacaagaau uagacaaaua caaaaacgca guaacagacc uacaauuacu uaugcaauca      420

acacccgcaa caggauccgg cucagcaauc uguucaggag uagcaguaug caaaguucuc      480

caccuagaag gcgaaguaaa caaaauaaaa ucagcccuau uaucuaccaa uaaagcagua      540

guaucacuau caaauggagu aucuguccua accuucaaag uacuugaccu aaaaaauuac      600

aucgacaaac aauuacuacc aauacuuaac aaacaaucau guucaauacc aaacauugaa      660

acaguaauag aauuucaaca aaaaaauaac agauuauuag aaauaacccg cgaauuuuca      720

guuaacgcag gaguaacaac accaguaucc acauacaugu uaacaaauuc agaacucuua      780

ucacuuauaa acgacaugcc cauaacaaac gaccaaaaaa aacucauguc uaacaauguu      840

caaauaguuc gacaacaauc auacuccaua augugcauaa uaaaagaaga aguucuagca      900

uauguuguac aacucccacu cuaugguguu auagacacac caugcuggaa acuacauaca      960

agccccuuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac ccgcacagac     1020

agaggcuggu auugcgauaa cgcagguuca guaucauucu uuccacaagc agaaacuugc     1080

aaaguccaau ccaauagagu cuucugcgac acuaugaacu cacucacacu cccaucugaa     1140

gucaauuuau guaacgucga uaucuucaac ccaaaauacg acugcaaaau aaugaccuca     1200

aaaacagacg uaagcucauc agucauaacu ucucuaggcg caaucgucuc auguuacggc     1260

aaaacaaaau guaccgcauc aaacaaaaau cgagguauaa uaaaaaccuu uucuaacggc     1320

ugcgacuacg uaucaaacaa aggaguagau acuguaagug ucggaaacac auuauacugc     1380

gucaacaaac aagaaggaca aucccuauau guuaaaggcg aaccuaucau uaauuucuac     1440

gacccacucg ucuuuccauc cgacgaauuu gacgcaucaa uuucccaagu aaaugaaaaa     1500

auaaaccaau cccuugcauu cauaagaaaa ucagaugaac uauuacacaa cguaaacgca     1560

ggcaaaucaa caacaaauau aaugaucaca acaauaauaa ucguaauaau aguaauccua     1620

cucucacuaa uagcaguagg cuuacuauua uauugcaaag ccagauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3031
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3031
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuuauccu aaaagcgaac gccauaacca caauccuaac agcagucacc      180

uucuguuucg ccucaggaca aaacaucacc gaggaauuuu accaauccac auguagcgcu      240

gucucaaaag gcuaccucgg cgcccuccga accggcuggu acacauccgu aauaacgauc      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgccaaagu caaacuuauc      360

aaacaagaac uagacaaaua caaaaacgcc gucaccgacc uccagcuccu caugcaaucc      420

accccagcaa caggcuccgg aagcgcaauc ugcucaggcg ucgccguaug caaaguacuc      480

caccucgaag gagaagucaa caaaaucaaa uccgcccucc uauccacaaa caaagcaguu      540

gucucacucu ccaacggggu aagcguacug accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuccuucc aauccucaac aaacaaucau gcucuauccc caacaucgaa      660

accguaaucg aauuucaaca aaaaaacaac cgccuacuug aaaucacacg cgaauuuagc      720

gucaacgcag gaguaacaac acccgugucc acauauaugc ucacgaacag cgaacuacua      780

ucccugauua acgacaugcc caucaccaac gaccaaaaaa aacuaaugag caacaacgua      840

caaaucgucc gccaacaaag cuacucuaua augugcauca ucaaggaaga aguccuagcc      900

uacgucgucc aauuaccacu cuacggcguc aucgacacac ccugcuggaa acuccauaca      960

uccccccucu gcaccaccaa caccaaagaa ggguccaaca uaugccucac ucgcacagac     1020

cgcggcuggu acugcgacaa cgcuggcagc gucagcuucu ucccccaggc cgaaaccugc     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cgcucacccu ccccuccgag     1140

gucaaccucu gcaacgucga cauauucaac cccaaauacg acugcaaaau caugaccucc     1200

aaaaccgacg ucagcucauc agucaucaca ucccucgggg ccaucgucuc cugcuacggc     1260

aaaaccaagu gcaccgccuc aaacaaaaac cgcggcauua ucaaaacauu cuccaacggc     1320

ugcgacuacg ucuccaacaa aggcgucgac acagucuccg ucgguaacac ccucuacugc     1380

guaaauaaac aagaaggcca aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccucucg ucuuccccuc cgacgaauuu gacgccucaa ucagccaagu uaacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa uccgacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua ccacgaacau caugaucacc accauaauca ucguaauuau cguaauacuc     1620

cuaucccuca uagcaguagg ccuccuacuc uacugcaaag cccguuaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3032
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3032
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3033
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3033
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3034
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3034
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3035
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3035
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3036
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3036
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3037
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3037
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3038
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3038
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuuaaa      120

gccaaugcaa uaaccacaau acuaacagca guaacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca aucaacaugu ucagcaguaa gcaaaggaua ccuaggagcc      240

uuacgcacag guugguacac uuccguaaua acaauagaac ucucaaauau aaaagaaaac      300

aaaugcaacg gaaccgaugc aaaaguaaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgcaguaa cagaccuaca auuacuuaug caaucaacac ccgcaacagg auccggcuca      420

gcaaucuguu caggaguagc aguaugcaaa guucuccacc uagaaggcga aguaaacaaa      480

auaaaaucag cccuauuauc uaccaauaaa gcaguaguau cacuaucaaa uggaguaucu      540

guccuaaccu ucaaaguacu ugaccuaaaa aauuacaucg acaaacaauu acuaccaaua      600

cuuaacaaac aaucauguuc aauaccaaac auugaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uauuagaaau aacccgcgaa uuuucaguua acgcaggagu aacaacacca      720

guauccacau acauguuaac aaauucagaa cucuuaucac uuauaaacga caugcccaua      780

acaaacgacc aaaaaaaacu caugucuaac aauguucaaa uaguucgaca acaaucauac      840

uccauaaugu gcauaauaaa agaagaaguu cuagcauaug uuguacaacu cccacucuau      900

gguguuauag acacaccaug cuggaaacua cauacaagcc ccuuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacccgc acagacagag gcugguauug cgauaacgca     1020

gguucaguau cauucuuucc acaagcagaa acuugcaaag uccaauccaa uagagucuuc     1080

ugcgacacua ugaacucacu cacacuccca ucugaaguca auuuauguaa cgucgauauc     1140

uucaacccaa aauacgacug caaaauaaug accucaaaaa cagacguaag cucaucaguc     1200

auaacuucuc uaggcgcaau cgucucaugu uacggcaaaa caaaauguac cgcaucaaac     1260

aaaaaucgag guauaauaaa aaccuuuucu aacggcugcg acuacguauc aaacaaagga     1320

guagauacug uaagugucgg aaacacauua uacugcguca acaaacaaga aggacaaucc     1380

cuauauguua aaggcgaacc uaucauuaau uucuacgacc cacucgucuu uccauccgac     1440

gaauuugacg caucaauuuc ccaaguaaau gaaaaaauaa accaaucccu ugcauucaua     1500

agaaaaucag augaacuauu acacaacgua aacgcaggca aaucaacaac aaauauaaug     1560

aucacaacaa uaauaaucgu aauaauagua auccuacucu cacuaauagc aguaggcuua     1620

cuauuauauu gcaaagccag auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3039
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3039
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu uauccuaaaa      120

gcgaacgcca uaaccacaau ccuaacagca gucaccuucu guuucgccuc aggacaaaac      180

aucaccgagg aauuuuacca auccacaugu agcgcugucu caaaaggcua ccucggcgcc      240

cuccgaaccg gcugguacac auccguaaua acgaucgaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc caaagucaaa cuuaucaaac aagaacuaga caaauacaaa      360

aacgccguca ccgaccucca gcuccucaug caauccaccc cagcaacagg cuccggaagc      420

gcaaucugcu caggcgucgc cguaugcaaa guacuccacc ucgaaggaga agucaacaaa      480

aucaaauccg cccuccuauc cacaaacaaa gcaguugucu cacucuccaa cgggguaagc      540

guacugaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu ccuuccaauc      600

cucaacaaac aaucaugcuc uauccccaac aucgaaaccg uaaucgaauu ucaacaaaaa      660

aacaaccgcc uacuugaaau cacacgcgaa uuuagcguca acgcaggagu aacaacaccc      720

guguccacau auaugcucac gaacagcgaa cuacuauccc ugauuaacga caugcccauc      780

accaacgacc aaaaaaaacu aaugagcaac aacguacaaa ucguccgcca acaaagcuac      840

ucuauaaugu gcaucaucaa ggaagaaguc cuagccuacg ucguccaauu accacucuac      900

ggcgucaucg acacacccug cuggaaacuc cauacauccc cccucugcac caccaacacc      960

aaagaagggu ccaacauaug ccucacucgc acagaccgcg gcugguacug cgacaacgcu     1020

ggcagcguca gcuucuuccc ccaggccgaa accugcaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucgcu cacccucccc uccgagguca accucugcaa cgucgacaua     1140

uucaacccca aauacgacug caaaaucaug accuccaaaa ccgacgucag cucaucaguc     1200

aucacauccc ucggggccau cgucuccugc uacggcaaaa ccaagugcac cgccucaaac     1260

aaaaaccgcg gcauuaucaa aacauucucc aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag ucuccgucgg uaacacccuc uacugcguaa auaaacaaga aggccaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cucucgucuu ccccuccgac     1440

gaauuugacg ccucaaucag ccaaguuaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaauccg acgaacuccu ccacaacguu aacgccggca aaucuaccac gaacaucaug     1560

aucaccacca uaaucaucgu aauuaucgua auacuccuau cccucauagc aguaggccuc     1620

cuacucuacu gcaaagcccg uuaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3040
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3040
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3041
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3041
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3042
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3042
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3043
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3043
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3044
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3044
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3045
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3045
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3046
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3046
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuuaaa      120

gccaaugcaa uaaccacaau acuaacagca guaacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca aucaacaugu ucagcaguaa gcaaaggaua ccuaggagcc      240

uuacgcacag guugguacac uuccguaaua acaauagaac ucucaaauau aaaagaaaac      300

aaaugcaacg gaaccgaugc aaaaguaaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgcaguaa cagaccuaca auuacuuaug caaucaacac ccgcaacagg auccggcuca      420

gcaaucuguu caggaguagc aguaugcaaa guucuccacc uagaaggcga aguaaacaaa      480

auaaaaucag cccuauuauc uaccaauaaa gcaguaguau cacuaucaaa uggaguaucu      540

guccuaaccu ucaaaguacu ugaccuaaaa aauuacaucg acaaacaauu acuaccaaua      600

cuuaacaaac aaucauguuc aauaccaaac auugaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uauuagaaau aacccgcgaa uuuucaguua acgcaggagu aacaacacca      720

guauccacau acauguuaac aaauucagaa cucuuaucac uuauaaacga caugcccaua      780

acaaacgacc aaaaaaaacu caugucuaac aauguucaaa uaguucgaca acaaucauac      840

uccauaaugu gcauaauaaa agaagaaguu cuagcauaug uuguacaacu cccacucuau      900

gguguuauag acacaccaug cuggaaacua cauacaagcc ccuuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacccgc acagacagag gcugguauug cgauaacgca     1020

gguucaguau cauucuuucc acaagcagaa acuugcaaag uccaauccaa uagagucuuc     1080

ugcgacacua ugaacucacu cacacuccca ucugaaguca auuuauguaa cgucgauauc     1140

uucaacccaa aauacgacug caaaauaaug accucaaaaa cagacguaag cucaucaguc     1200

auaacuucuc uaggcgcaau cgucucaugu uacggcaaaa caaaauguac cgcaucaaac     1260

aaaaaucgag guauaauaaa aaccuuuucu aacggcugcg acuacguauc aaacaaagga     1320

guagauacug uaagugucgg aaacacauua uacugcguca acaaacaaga aggacaaucc     1380

cuauauguua aaggcgaacc uaucauuaau uucuacgacc cacucgucuu uccauccgac     1440

gaauuugacg caucaauuuc ccaaguaaau gaaaaaauaa accaaucccu ugcauucaua     1500

agaaaaucag augaacuauu acacaacgua aacgcaggca aaucaacaac aaauauaaug     1560

aucacaacaa uaauaaucgu aauaauagua auccuacucu cacuaauagc aguaggcuua     1620

cuauuauauu gcaaagccag auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3047
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3047
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu uauccuaaaa      120

gcgaacgcca uaaccacaau ccuaacagca gucaccuucu guuucgccuc aggacaaaac      180

aucaccgagg aauuuuacca auccacaugu agcgcugucu caaaaggcua ccucggcgcc      240

cuccgaaccg gcugguacac auccguaaua acgaucgaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc caaagucaaa cuuaucaaac aagaacuaga caaauacaaa      360

aacgccguca ccgaccucca gcuccucaug caauccaccc cagcaacagg cuccggaagc      420

gcaaucugcu caggcgucgc cguaugcaaa guacuccacc ucgaaggaga agucaacaaa      480

aucaaauccg cccuccuauc cacaaacaaa gcaguugucu cacucuccaa cgggguaagc      540

guacugaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu ccuuccaauc      600

cucaacaaac aaucaugcuc uauccccaac aucgaaaccg uaaucgaauu ucaacaaaaa      660

aacaaccgcc uacuugaaau cacacgcgaa uuuagcguca acgcaggagu aacaacaccc      720

guguccacau auaugcucac gaacagcgaa cuacuauccc ugauuaacga caugcccauc      780

accaacgacc aaaaaaaacu aaugagcaac aacguacaaa ucguccgcca acaaagcuac      840

ucuauaaugu gcaucaucaa ggaagaaguc cuagccuacg ucguccaauu accacucuac      900

ggcgucaucg acacacccug cuggaaacuc cauacauccc cccucugcac caccaacacc      960

aaagaagggu ccaacauaug ccucacucgc acagaccgcg gcugguacug cgacaacgcu     1020

ggcagcguca gcuucuuccc ccaggccgaa accugcaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucgcu cacccucccc uccgagguca accucugcaa cgucgacaua     1140

uucaacccca aauacgacug caaaaucaug accuccaaaa ccgacgucag cucaucaguc     1200

aucacauccc ucggggccau cgucuccugc uacggcaaaa ccaagugcac cgccucaaac     1260

aaaaaccgcg gcauuaucaa aacauucucc aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag ucuccgucgg uaacacccuc uacugcguaa auaaacaaga aggccaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cucucgucuu ccccuccgac     1440

gaauuugacg ccucaaucag ccaaguuaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaauccg acgaacuccu ccacaacguu aacgccggca aaucuaccac gaacaucaug     1560

aucaccacca uaaucaucgu aauuaucgua auacuccuau cccucauagc aguaggccuc     1620

cuacucuacu gcaaagcccg uuaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3048
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3048
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3049
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3049
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3050
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3050
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3051
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3051
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3052
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3052
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3053
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3053
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3054
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3054
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuuaaa      120

gccaaugcaa uaaccacaau acuaacagca guaacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca aucaacaugu ucagcaguaa gcaaaggaua ccuaggagcc      240

uuacgcacag guugguacac uuccguaaua acaauagaac ucucaaauau aaaagaaaac      300

aaaugcaacg gaaccgaugc aaaaguaaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgcaguaa cagaccuaca auuacuuaug caaucaacac ccgcaacagg auccggcuca      420

gcaaucuguu caggaguagc aguaugcaaa guucuccacc uagaaggcga aguaaacaaa      480

auaaaaucag cccuauuauc uaccaauaaa gcaguaguau cacuaucaaa uggaguaucu      540

guccuaaccu ucaaaguacu ugaccuaaaa aauuacaucg acaaacaauu acuaccaaua      600

cuuaacaaac aaucauguuc aauaccaaac auugaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uauuagaaau aacccgcgaa uuuucaguua acgcaggagu aacaacacca      720

guauccacau acauguuaac aaauucagaa cucuuaucac uuauaaacga caugcccaua      780

acaaacgacc aaaaaaaacu caugucuaac aauguucaaa uaguucgaca acaaucauac      840

uccauaaugu gcauaauaaa agaagaaguu cuagcauaug uuguacaacu cccacucuau      900

gguguuauag acacaccaug cuggaaacua cauacaagcc ccuuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacccgc acagacagag gcugguauug cgauaacgca     1020

gguucaguau cauucuuucc acaagcagaa acuugcaaag uccaauccaa uagagucuuc     1080

ugcgacacua ugaacucacu cacacuccca ucugaaguca auuuauguaa cgucgauauc     1140

uucaacccaa aauacgacug caaaauaaug accucaaaaa cagacguaag cucaucaguc     1200

auaacuucuc uaggcgcaau cgucucaugu uacggcaaaa caaaauguac cgcaucaaac     1260

aaaaaucgag guauaauaaa aaccuuuucu aacggcugcg acuacguauc aaacaaagga     1320

guagauacug uaagugucgg aaacacauua uacugcguca acaaacaaga aggacaaucc     1380

cuauauguua aaggcgaacc uaucauuaau uucuacgacc cacucgucuu uccauccgac     1440

gaauuugacg caucaauuuc ccaaguaaau gaaaaaauaa accaaucccu ugcauucaua     1500

agaaaaucag augaacuauu acacaacgua aacgcaggca aaucaacaac aaauauaaug     1560

aucacaacaa uaauaaucgu aauaauagua auccuacucu cacuaauagc aguaggcuua     1620

cuauuauauu gcaaagccag auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3055
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3055
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu uauccuaaaa      120

gcgaacgcca uaaccacaau ccuaacagca gucaccuucu guuucgccuc aggacaaaac      180

aucaccgagg aauuuuacca auccacaugu agcgcugucu caaaaggcua ccucggcgcc      240

cuccgaaccg gcugguacac auccguaaua acgaucgaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc caaagucaaa cuuaucaaac aagaacuaga caaauacaaa      360

aacgccguca ccgaccucca gcuccucaug caauccaccc cagcaacagg cuccggaagc      420

gcaaucugcu caggcgucgc cguaugcaaa guacuccacc ucgaaggaga agucaacaaa      480

aucaaauccg cccuccuauc cacaaacaaa gcaguugucu cacucuccaa cgggguaagc      540

guacugaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu ccuuccaauc      600

cucaacaaac aaucaugcuc uauccccaac aucgaaaccg uaaucgaauu ucaacaaaaa      660

aacaaccgcc uacuugaaau cacacgcgaa uuuagcguca acgcaggagu aacaacaccc      720

guguccacau auaugcucac gaacagcgaa cuacuauccc ugauuaacga caugcccauc      780

accaacgacc aaaaaaaacu aaugagcaac aacguacaaa ucguccgcca acaaagcuac      840

ucuauaaugu gcaucaucaa ggaagaaguc cuagccuacg ucguccaauu accacucuac      900

ggcgucaucg acacacccug cuggaaacuc cauacauccc cccucugcac caccaacacc      960

aaagaagggu ccaacauaug ccucacucgc acagaccgcg gcugguacug cgacaacgcu     1020

ggcagcguca gcuucuuccc ccaggccgaa accugcaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucgcu cacccucccc uccgagguca accucugcaa cgucgacaua     1140

uucaacccca aauacgacug caaaaucaug accuccaaaa ccgacgucag cucaucaguc     1200

aucacauccc ucggggccau cgucuccugc uacggcaaaa ccaagugcac cgccucaaac     1260

aaaaaccgcg gcauuaucaa aacauucucc aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag ucuccgucgg uaacacccuc uacugcguaa auaaacaaga aggccaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cucucgucuu ccccuccgac     1440

gaauuugacg ccucaaucag ccaaguuaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaauccg acgaacuccu ccacaacguu aacgccggca aaucuaccac gaacaucaug     1560

aucaccacca uaaucaucgu aauuaucgua auacuccuau cccucauagc aguaggccuc     1620

cuacucuacu gcaaagcccg uuaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3056
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3056
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3057
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3057
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3058
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3058
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3059
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3059
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuauauguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaacaaa      480

aucaagagcg cccugcugag uacgaauaaa gcuguggucu cccucucuaa cggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacauug acaaacaauu gcugccuauc      600

cuaaacaagc aguccuguuc aauuccaaau aucgaaaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuaguguca acgccggagu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucaucaacga uaugcccauu      780

acgaacgacc aaaagaaacu gaugucaaau aacguccaga ucguucgcca gcagagcuac      840

aguaucaugu gcauuauaaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucaucg auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaaggcu ccaacauuug uuugacccga acggaccgug ggugguacug cgauaaugca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauauc     1140

uuuaacccca aauaugacug uaagauaaug accaguaaaa cagauguaag cuccucuguu     1200

auuacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaau     1260

aagaacaggg ggaucauuaa gaccuucucc aauggaugcg acuaugucag caacaaaggc     1320

guggacacug ucucuguggg uaauacgcuu uacuguguua acaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcauauc ccaggucaau gagaagauca accagucucu cgcuuucauu     1500

cggaaaucgg acgaacuguu acacaaugug aacgccggca agagcacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuau cccucaucgc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3060
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3060
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3061
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3061
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuauuugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaacaaa      480

aucaaguccg cgcuucugag caccaauaaa gccgucgugu cucucuccaa cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacauug acaaacaacu ccugccuauc      600

cugaacaagc agucuuguuc cauuccgaau aucgaaaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugaucaacga uaugccuauu      780

accaacgacc aaaagaaacu uauguccaau aacgugcaga ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggau ccaacaucug ucugacacgg accgaccgcg gcugguacug cgauaaugcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauu     1140

uuuaacccca aauaugacug uaagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ugggagcgau cgugucuugc uacggcaaga caaaauguac ggccuccaau     1260

aagaaccggg ggauuaucaa gaccuucagc aauggaugcg acuauguuuc uaacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uaucauuaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuaucag ccaggugaau gagaagauua accagucccu ggccuucauc     1500

cgcaaaucug acgaacugcu ccacaaugug aacgcuggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cccugaucgc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3062
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3062
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuuaaa      120

gccaaugcaa uaaccacaau acuaacagca guaacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca aucaacaugu ucagcaguaa gcaaaggaua ccuaggagcc      240

uuacgcacag guugguacac uuccguaaua acaauagaac ucucaaauau aaaagaaaac      300

aaaugcaacg gaaccgaugc aaaaguaaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgcaguaa cagaccuaca auuacuuaug caaucaacac ccgcaacagg auccggcuca      420

gcaaucuguu caggaguagc aguaugcaaa guucuccacc uagaaggcga aguaaacaaa      480

auaaaaucag cccuauuauc uaccaauaaa gcaguaguau cacuaucaaa uggaguaucu      540

guccuaaccu ucaaaguacu ugaccuaaaa aauuacaucg acaaacaauu acuaccaaua      600

cuuaacaaac aaucauguuc aauaccaaac auugaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uauuagaaau aacccgcgaa uuuucaguua acgcaggagu aacaacacca      720

guauccacau acauguuaac aaauucagaa cucuuaucac uuauaaacga caugcccaua      780

acaaacgacc aaaaaaaacu caugucuaac aauguucaaa uaguucgaca acaaucauac      840

uccauaaugu gcauaauaaa agaagaaguu cuagcauaug uuguacaacu cccacucuau      900

gguguuauag acacaccaug cuggaaacua cauacaagcc ccuuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacccgc acagacagag gcugguauug cgauaacgca     1020

gguucaguau cauucuuucc acaagcagaa acuugcaaag uccaauccaa uagagucuuc     1080

ugcgacacua ugaacucacu cacacuccca ucugaaguca auuuauguaa cgucgauauc     1140

uucaacccaa aauacgacug caaaauaaug accucaaaaa cagacguaag cucaucaguc     1200

auaacuucuc uaggcgcaau cgucucaugu uacggcaaaa caaaauguac cgcaucaaac     1260

aaaaaucgag guauaauaaa aaccuuuucu aacggcugcg acuacguauc aaacaaagga     1320

guagauacug uaagugucgg aaacacauua uacugcguca acaaacaaga aggacaaucc     1380

cuauauguua aaggcgaacc uaucauuaau uucuacgacc cacucgucuu uccauccgac     1440

gaauuugacg caucaauuuc ccaaguaaau gaaaaaauaa accaaucccu ugcauucaua     1500

agaaaaucag augaacuauu acacaacgua aacgcaggca aaucaacaac aaauauaaug     1560

aucacaacaa uaauaaucgu aauaauagua auccuacucu cacuaauagc aguaggcuua     1620

cuauuauauu gcaaagccag auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3063
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3063
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu uauccuaaaa      120

gcgaacgcca uaaccacaau ccuaacagca gucaccuucu guuucgccuc aggacaaaac      180

aucaccgagg aauuuuacca auccacaugu agcgcugucu caaaaggcua ccucggcgcc      240

cuccgaaccg gcugguacac auccguaaua acgaucgaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc caaagucaaa cuuaucaaac aagaacuaga caaauacaaa      360

aacgccguca ccgaccucca gcuccucaug caauccaccc cagcaacagg cuccggaagc      420

gcaaucugcu caggcgucgc cguaugcaaa guacuccacc ucgaaggaga agucaacaaa      480

aucaaauccg cccuccuauc cacaaacaaa gcaguugucu cacucuccaa cgggguaagc      540

guacugaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu ccuuccaauc      600

cucaacaaac aaucaugcuc uauccccaac aucgaaaccg uaaucgaauu ucaacaaaaa      660

aacaaccgcc uacuugaaau cacacgcgaa uuuagcguca acgcaggagu aacaacaccc      720

guguccacau auaugcucac gaacagcgaa cuacuauccc ugauuaacga caugcccauc      780

accaacgacc aaaaaaaacu aaugagcaac aacguacaaa ucguccgcca acaaagcuac      840

ucuauaaugu gcaucaucaa ggaagaaguc cuagccuacg ucguccaauu accacucuac      900

ggcgucaucg acacacccug cuggaaacuc cauacauccc cccucugcac caccaacacc      960

aaagaagggu ccaacauaug ccucacucgc acagaccgcg gcugguacug cgacaacgcu     1020

ggcagcguca gcuucuuccc ccaggccgaa accugcaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucgcu cacccucccc uccgagguca accucugcaa cgucgacaua     1140

uucaacccca aauacgacug caaaaucaug accuccaaaa ccgacgucag cucaucaguc     1200

aucacauccc ucggggccau cgucuccugc uacggcaaaa ccaagugcac cgccucaaac     1260

aaaaaccgcg gcauuaucaa aacauucucc aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag ucuccgucgg uaacacccuc uacugcguaa auaaacaaga aggccaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cucucgucuu ccccuccgac     1440

gaauuugacg ccucaaucag ccaaguuaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaauccg acgaacuccu ccacaacguu aacgccggca aaucuaccac gaacaucaug     1560

aucaccacca uaaucaucgu aauuaucgua auacuccuau cccucauagc aguaggccuc     1620

cuacucuacu gcaaagcccg uuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3064
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3064
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3065
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3065
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3066
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3066
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3067
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3067
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3068
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3068
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3069
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3069
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3070
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3070
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uuaaagccaa ugcaauaacc acaauacuaa cagcaguaac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucaa cauguucagc aguaagcaaa      300

ggauaccuag gagccuuacg cacagguugg uacacuuccg uaauaacaau agaacucuca      360

aauauaaaag aaaacaaaug caacggaacc gaugcaaaag uaaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc aguaacagac cuacaauuac uuaugcaauc aacacccgca      480

acaggauccg gcucagcaau cuguucagga guagcaguau gcaaaguucu ccaccuagaa      540

ggcgaaguaa acaaaauaaa aucagcccua uuaucuacca auaaagcagu aguaucacua      600

ucaaauggag uaucuguccu aaccuucaaa guacuugacc uaaaaaauua caucgacaaa      660

caauuacuac caauacuuaa caaacaauca uguucaauac caaacauuga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuauua gaaauaaccc gcgaauuuuc aguuaacgca      780

ggaguaacaa caccaguauc cacauacaug uuaacaaauu cagaacucuu aucacuuaua      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu cuaacaaugu ucaaauaguu      900

cgacaacaau cauacuccau aaugugcaua auaaaagaag aaguucuagc auauguugua      960

caacucccac ucuauggugu uauagacaca ccaugcugga aacuacauac aagccccuua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa cccgcacaga cagaggcugg     1080

uauugcgaua acgcagguuc aguaucauuc uuuccacaag cagaaacuug caaaguccaa     1140

uccaauagag ucuucugcga cacuaugaac ucacucacac ucccaucuga agucaauuua     1200

uguaacgucg auaucuucaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guaagcucau cagucauaac uucucuaggc gcaaucgucu cauguuacgg caaaacaaaa     1320

uguaccgcau caaacaaaaa ucgagguaua auaaaaaccu uuucuaacgg cugcgacuac     1380

guaucaaaca aaggaguaga uacuguaagu gucggaaaca cauuauacug cgucaacaaa     1440

caagaaggac aaucccuaua uguuaaaggc gaaccuauca uuaauuucua cgacccacuc     1500

gucuuuccau ccgacgaauu ugacgcauca auuucccaag uaaaugaaaa aauaaaccaa     1560

ucccuugcau ucauaagaaa aucagaugaa cuauuacaca acguaaacgc aggcaaauca     1620

acaacaaaua uaaugaucac aacaauaaua aucguaauaa uaguaauccu acucucacua     1680

auagcaguag gcuuacuauu auauugcaaa gccagauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3071
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3071
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuuaucc uaaaagcgaa cgccauaacc acaauccuaa cagcagucac cuucuguuuc      240

gccucaggac aaaacaucac cgaggaauuu uaccaaucca cauguagcgc ugucucaaaa      300

ggcuaccucg gcgcccuccg aaccggcugg uacacauccg uaauaacgau cgaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgccaaag ucaaacuuau caaacaagaa      420

cuagacaaau acaaaaacgc cgucaccgac cuccagcucc ucaugcaauc caccccagca      480

acaggcuccg gaagcgcaau cugcucaggc gucgccguau gcaaaguacu ccaccucgaa      540

ggagaaguca acaaaaucaa auccgcccuc cuauccacaa acaaagcagu ugucucacuc      600

uccaacgggg uaagcguacu gaccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuccuuc caauccucaa caaacaauca ugcucuaucc ccaacaucga aaccguaauc      720

gaauuucaac aaaaaaacaa ccgccuacuu gaaaucacac gcgaauuuag cgucaacgca      780

ggaguaacaa cacccguguc cacauauaug cucacgaaca gcgaacuacu aucccugauu      840

aacgacaugc ccaucaccaa cgaccaaaaa aaacuaauga gcaacaacgu acaaaucguc      900

cgccaacaaa gcuacucuau aaugugcauc aucaaggaag aaguccuagc cuacgucguc      960

caauuaccac ucuacggcgu caucgacaca cccugcugga aacuccauac auccccccuc     1020

ugcaccacca acaccaaaga aggguccaac auaugccuca cucgcacaga ccgcggcugg     1080

uacugcgaca acgcuggcag cgucagcuuc uucccccagg ccgaaaccug caaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucgcucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caaaaccgac     1260

gucagcucau cagucaucac aucccucggg gccaucgucu ccugcuacgg caaaaccaag     1320

ugcaccgccu caaacaaaaa ccgcggcauu aucaaaacau ucuccaacgg cugcgacuac     1380

gucuccaaca aaggcgucga cacagucucc gucgguaaca cccucuacug cguaaauaaa     1440

caagaaggcc aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccucuc     1500

gucuuccccu ccgacgaauu ugacgccuca aucagccaag uuaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa auccgacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

accacgaaca ucaugaucac caccauaauc aucguaauua ucguaauacu ccuaucccuc     1680

auagcaguag gccuccuacu cuacugcaaa gcccguuaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3072
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3072
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3073
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3073
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3074
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3074
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3075
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3075
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3076
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3076
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3077
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3077
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3078
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3078
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uuaaagccaa ugcaauaacc acaauacuaa cagcaguaac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucaa cauguucagc aguaagcaaa      300

ggauaccuag gagccuuacg cacagguugg uacacuuccg uaauaacaau agaacucuca      360

aauauaaaag aaaacaaaug caacggaacc gaugcaaaag uaaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc aguaacagac cuacaauuac uuaugcaauc aacacccgca      480

acaggauccg gcucagcaau cuguucagga guagcaguau gcaaaguucu ccaccuagaa      540

ggcgaaguaa acaaaauaaa aucagcccua uuaucuacca auaaagcagu aguaucacua      600

ucaaauggag uaucuguccu aaccuucaaa guacuugacc uaaaaaauua caucgacaaa      660

caauuacuac caauacuuaa caaacaauca uguucaauac caaacauuga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuauua gaaauaaccc gcgaauuuuc aguuaacgca      780

ggaguaacaa caccaguauc cacauacaug uuaacaaauu cagaacucuu aucacuuaua      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu cuaacaaugu ucaaauaguu      900

cgacaacaau cauacuccau aaugugcaua auaaaagaag aaguucuagc auauguugua      960

caacucccac ucuauggugu uauagacaca ccaugcugga aacuacauac aagccccuua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa cccgcacaga cagaggcugg     1080

uauugcgaua acgcagguuc aguaucauuc uuuccacaag cagaaacuug caaaguccaa     1140

uccaauagag ucuucugcga cacuaugaac ucacucacac ucccaucuga agucaauuua     1200

uguaacgucg auaucuucaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guaagcucau cagucauaac uucucuaggc gcaaucgucu cauguuacgg caaaacaaaa     1320

uguaccgcau caaacaaaaa ucgagguaua auaaaaaccu uuucuaacgg cugcgacuac     1380

guaucaaaca aaggaguaga uacuguaagu gucggaaaca cauuauacug cgucaacaaa     1440

caagaaggac aaucccuaua uguuaaaggc gaaccuauca uuaauuucua cgacccacuc     1500

gucuuuccau ccgacgaauu ugacgcauca auuucccaag uaaaugaaaa aauaaaccaa     1560

ucccuugcau ucauaagaaa aucagaugaa cuauuacaca acguaaacgc aggcaaauca     1620

acaacaaaua uaaugaucac aacaauaaua aucguaauaa uaguaauccu acucucacua     1680

auagcaguag gcuuacuauu auauugcaaa gccagauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3079
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3079
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuuaucc uaaaagcgaa cgccauaacc acaauccuaa cagcagucac cuucuguuuc      240

gccucaggac aaaacaucac cgaggaauuu uaccaaucca cauguagcgc ugucucaaaa      300

ggcuaccucg gcgcccuccg aaccggcugg uacacauccg uaauaacgau cgaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgccaaag ucaaacuuau caaacaagaa      420

cuagacaaau acaaaaacgc cgucaccgac cuccagcucc ucaugcaauc caccccagca      480

acaggcuccg gaagcgcaau cugcucaggc gucgccguau gcaaaguacu ccaccucgaa      540

ggagaaguca acaaaaucaa auccgcccuc cuauccacaa acaaagcagu ugucucacuc      600

uccaacgggg uaagcguacu gaccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuccuuc caauccucaa caaacaauca ugcucuaucc ccaacaucga aaccguaauc      720

gaauuucaac aaaaaaacaa ccgccuacuu gaaaucacac gcgaauuuag cgucaacgca      780

ggaguaacaa cacccguguc cacauauaug cucacgaaca gcgaacuacu aucccugauu      840

aacgacaugc ccaucaccaa cgaccaaaaa aaacuaauga gcaacaacgu acaaaucguc      900

cgccaacaaa gcuacucuau aaugugcauc aucaaggaag aaguccuagc cuacgucguc      960

caauuaccac ucuacggcgu caucgacaca cccugcugga aacuccauac auccccccuc     1020

ugcaccacca acaccaaaga aggguccaac auaugccuca cucgcacaga ccgcggcugg     1080

uacugcgaca acgcuggcag cgucagcuuc uucccccagg ccgaaaccug caaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucgcucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caaaaccgac     1260

gucagcucau cagucaucac aucccucggg gccaucgucu ccugcuacgg caaaaccaag     1320

ugcaccgccu caaacaaaaa ccgcggcauu aucaaaacau ucuccaacgg cugcgacuac     1380

gucuccaaca aaggcgucga cacagucucc gucgguaaca cccucuacug cguaaauaaa     1440

caagaaggcc aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccucuc     1500

gucuuccccu ccgacgaauu ugacgccuca aucagccaag uuaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa auccgacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

accacgaaca ucaugaucac caccauaauc aucguaauua ucguaauacu ccuaucccuc     1680

auagcaguag gccuccuacu cuacugcaaa gcccguuaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3080
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3080
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3081
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3081
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3082
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3082
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3083
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3083
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau auguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua acaaaaucaa gagcgcccug cugaguacga auaaagcugu ggucucccuc      600

ucuaacgggg ugagcguauu aacuuuuaag guucuggauc uuaagaauua cauugacaaa      660

caauugcugc cuauccuaaa caagcagucc uguucaauuc caaauaucga aaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuag ugucaacgcc      780

ggagugacua ccccggugag cacauauaug cuuaccaauu cugagcuguu gucccucauc      840

aacgauaugc ccauuacgaa cgaccaaaag aaacugaugu caaauaacgu ccagaucguu      900

cgccagcaga gcuacaguau caugugcauu auaaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu caucgauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua auacaaagga aggcuccaac auuuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua augcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaacagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaaugugg auaucuuuaa ccccaaauau gacuguaaga uaaugaccag uaaaacagau     1260

guaagcuccu cuguuauuac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaauaagaa cagggggauc auuaagaccu ucuccaaugg augcgacuau     1380

gucagcaaca aaggcgugga cacugucucu guggguaaua cgcuuuacug uguuaacaag     1440

caagaggggc agucacugua ugugaaagga gagccuauca uuaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc auaucccagg ucaaugagaa gaucaaccag     1560

ucucucgcuu ucauucggaa aucggacgaa cuguuacaca augugaacgc cggcaagagc     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaucccuc     1680

aucgcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3084
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3084
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3085
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3085
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau uuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga acaaaaucaa guccgcgcuu cugagcacca auaaagccgu cgugucucuc      600

uccaacggcg uuagcgugcu gacauuuaag guccuugauc ugaagaauua cauugacaaa      660

caacuccugc cuauccugaa caagcagucu uguuccauuc cgaauaucga aaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuag cgugaacgcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaauu ccgagcugcu cagccugauc      840

aacgauaugc cuauuaccaa cgaccaaaag aaacuuaugu ccaauaacgu gcagaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa auaccaagga aggauccaac aucugucuga cacggaccga ccgcggcugg     1080

uacugcgaua augcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaacagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaaugucg auauuuuuaa ccccaaauau gacuguaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccuggga gcgaucgugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaauaagaa ccgggggauu aucaagaccu ucagcaaugg augcgacuau     1380

guuucuaaca aaggcgugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagaggggc agagccugua ugugaaagga gagccuauca uuaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu aucagccagg ugaaugagaa gauuaaccag     1560

ucccuggccu ucauccgcaa aucugacgaa cugcuccaca augugaacgc uggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucccug     1680

aucgccgugg ggcuccugcu guauugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3086
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3086
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uuaaagccaa ugcaauaacc acaauacuaa cagcaguaac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucaa cauguucagc aguaagcaaa      300

ggauaccuag gagccuuacg cacagguugg uacacuuccg uaauaacaau agaacucuca      360

aauauaaaag aaaacaaaug caacggaacc gaugcaaaag uaaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc aguaacagac cuacaauuac uuaugcaauc aacacccgca      480

acaggauccg gcucagcaau cuguucagga guagcaguau gcaaaguucu ccaccuagaa      540

ggcgaaguaa acaaaauaaa aucagcccua uuaucuacca auaaagcagu aguaucacua      600

ucaaauggag uaucuguccu aaccuucaaa guacuugacc uaaaaaauua caucgacaaa      660

caauuacuac caauacuuaa caaacaauca uguucaauac caaacauuga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuauua gaaauaaccc gcgaauuuuc aguuaacgca      780

ggaguaacaa caccaguauc cacauacaug uuaacaaauu cagaacucuu aucacuuaua      840

aacgacaugc ccauaacaaa cgaccaaaaa aaacucaugu cuaacaaugu ucaaauaguu      900

cgacaacaau cauacuccau aaugugcaua auaaaagaag aaguucuagc auauguugua      960

caacucccac ucuauggugu uauagacaca ccaugcugga aacuacauac aagccccuua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa cccgcacaga cagaggcugg     1080

uauugcgaua acgcagguuc aguaucauuc uuuccacaag cagaaacuug caaaguccaa     1140

uccaauagag ucuucugcga cacuaugaac ucacucacac ucccaucuga agucaauuua     1200

uguaacgucg auaucuucaa cccaaaauac gacugcaaaa uaaugaccuc aaaaacagac     1260

guaagcucau cagucauaac uucucuaggc gcaaucgucu cauguuacgg caaaacaaaa     1320

uguaccgcau caaacaaaaa ucgagguaua auaaaaaccu uuucuaacgg cugcgacuac     1380

guaucaaaca aaggaguaga uacuguaagu gucggaaaca cauuauacug cgucaacaaa     1440

caagaaggac aaucccuaua uguuaaaggc gaaccuauca uuaauuucua cgacccacuc     1500

gucuuuccau ccgacgaauu ugacgcauca auuucccaag uaaaugaaaa aauaaaccaa     1560

ucccuugcau ucauaagaaa aucagaugaa cuauuacaca acguaaacgc aggcaaauca     1620

acaacaaaua uaaugaucac aacaauaaua aucguaauaa uaguaauccu acucucacua     1680

auagcaguag gcuuacuauu auauugcaaa gccagauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3087
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3087
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuuaucc uaaaagcgaa cgccauaacc acaauccuaa cagcagucac cuucuguuuc      240

gccucaggac aaaacaucac cgaggaauuu uaccaaucca cauguagcgc ugucucaaaa      300

ggcuaccucg gcgcccuccg aaccggcugg uacacauccg uaauaacgau cgaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgccaaag ucaaacuuau caaacaagaa      420

cuagacaaau acaaaaacgc cgucaccgac cuccagcucc ucaugcaauc caccccagca      480

acaggcuccg gaagcgcaau cugcucaggc gucgccguau gcaaaguacu ccaccucgaa      540

ggagaaguca acaaaaucaa auccgcccuc cuauccacaa acaaagcagu ugucucacuc      600

uccaacgggg uaagcguacu gaccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuccuuc caauccucaa caaacaauca ugcucuaucc ccaacaucga aaccguaauc      720

gaauuucaac aaaaaaacaa ccgccuacuu gaaaucacac gcgaauuuag cgucaacgca      780

ggaguaacaa cacccguguc cacauauaug cucacgaaca gcgaacuacu aucccugauu      840

aacgacaugc ccaucaccaa cgaccaaaaa aaacuaauga gcaacaacgu acaaaucguc      900

cgccaacaaa gcuacucuau aaugugcauc aucaaggaag aaguccuagc cuacgucguc      960

caauuaccac ucuacggcgu caucgacaca cccugcugga aacuccauac auccccccuc     1020

ugcaccacca acaccaaaga aggguccaac auaugccuca cucgcacaga ccgcggcugg     1080

uacugcgaca acgcuggcag cgucagcuuc uucccccagg ccgaaaccug caaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucgcucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acauauucaa ccccaaauac gacugcaaaa ucaugaccuc caaaaccgac     1260

gucagcucau cagucaucac aucccucggg gccaucgucu ccugcuacgg caaaaccaag     1320

ugcaccgccu caaacaaaaa ccgcggcauu aucaaaacau ucuccaacgg cugcgacuac     1380

gucuccaaca aaggcgucga cacagucucc gucgguaaca cccucuacug cguaaauaaa     1440

caagaaggcc aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccucuc     1500

gucuuccccu ccgacgaauu ugacgccuca aucagccaag uuaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa auccgacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

accacgaaca ucaugaucac caccauaauc aucguaauua ucguaauacu ccuaucccuc     1680

auagcaguag gccuccuacu cuacugcaaa gcccguuaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3088
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3088
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3089
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3089
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3090
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3090
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3091
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3091
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uauauguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaacaaaau caagagcgcc cugcugagua cgaauaaagc uguggucucc      480

cucucuaacg gggugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacauugac      540

aaacaauugc ugccuauccu aaacaagcag uccuguucaa uuccaaauau cgaaaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uagugucaac      660

gccggaguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      720

aucaacgaua ugcccauuac gaacgaccaa aagaaacuga ugucaaauaa cguccagauc      780

guucgccagc agagcuacag uaucaugugc auuauaaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucaucgau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaauacaaa ggaaggcucc aacauuuguu ugacccgaac ggaccguggg      960

ugguacugcg auaaugcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaaug uggauaucuu uaaccccaaa uaugacugua agauaaugac caguaaaaca     1140

gauguaagcu ccucuguuau uacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaauaa gaacaggggg aucauuaaga ccuucuccaa uggaugcgac     1260

uaugucagca acaaaggcgu ggacacuguc ucugugggua auacgcuuua cuguguuaac     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua ucauuaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcauauccc aggucaauga gaagaucaac     1440

cagucucucg cuuucauucg gaaaucggac gaacuguuac acaaugugaa cgccggcaag     1500

agcacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaucc     1560

cucaucgcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3092
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3092
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3093
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3093
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uauuuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaacaaaau caaguccgcg cuucugagca ccaauaaagc cgucgugucu      480

cucuccaacg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacauugac      540

aaacaacucc ugccuauccu gaacaagcag ucuuguucca uuccgaauau cgaaaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      660

gcuggcguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      720

aucaacgaua ugccuauuac caacgaccaa aagaaacuua uguccaauaa cgugcagauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaauaccaa ggaaggaucc aacaucuguc ugacacggac cgaccgcggc      960

ugguacugcg auaaugcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaaug ucgauauuuu uaaccccaaa uaugacugua agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccug ggagcgaucg ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaauaa gaaccggggg auuaucaaga ccuucagcaa uggaugcgac     1260

uauguuucua acaaaggcgu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua ucauuaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuaucagcc aggugaauga gaagauuaac     1440

cagucccugg ccuucauccg caaaucugac gaacugcucc acaaugugaa cgcuggcaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucc     1560

cugaucgccg uggggcuccu gcuguauugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3094
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3094
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuaa uacuuaaagc caaugcaaua accacaauac uaacagcagu aacauucugc      120

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau caacauguuc agcaguaagc      180

aaaggauacc uaggagccuu acgcacaggu ugguacacuu ccguaauaac aauagaacuc      240

ucaaauauaa aagaaaacaa augcaacgga accgaugcaa aaguaaaacu aauaaaacaa      300

gaauuagaca aauacaaaaa cgcaguaaca gaccuacaau uacuuaugca aucaacaccc      360

gcaacaggau ccggcucagc aaucuguuca ggaguagcag uaugcaaagu ucuccaccua      420

gaaggcgaag uaaacaaaau aaaaucagcc cuauuaucua ccaauaaagc aguaguauca      480

cuaucaaaug gaguaucugu ccuaaccuuc aaaguacuug accuaaaaaa uuacaucgac      540

aaacaauuac uaccaauacu uaacaaacaa ucauguucaa uaccaaacau ugaaacagua      600

auagaauuuc aacaaaaaaa uaacagauua uuagaaauaa cccgcgaauu uucaguuaac      660

gcaggaguaa caacaccagu auccacauac auguuaacaa auucagaacu cuuaucacuu      720

auaaacgaca ugcccauaac aaacgaccaa aaaaaacuca ugucuaacaa uguucaaaua      780

guucgacaac aaucauacuc cauaaugugc auaauaaaag aagaaguucu agcauauguu      840

guacaacucc cacucuaugg uguuauagac acaccaugcu ggaaacuaca uacaagcccc      900

uuaugcacua caaacacaaa agaaggcucu aauauauguc uaacccgcac agacagaggc      960

ugguauugcg auaacgcagg uucaguauca uucuuuccac aagcagaaac uugcaaaguc     1020

caauccaaua gagucuucug cgacacuaug aacucacuca cacucccauc ugaagucaau     1080

uuauguaacg ucgauaucuu caacccaaaa uacgacugca aaauaaugac cucaaaaaca     1140

gacguaagcu caucagucau aacuucucua ggcgcaaucg ucucauguua cggcaaaaca     1200

aaauguaccg caucaaacaa aaaucgaggu auaauaaaaa ccuuuucuaa cggcugcgac     1260

uacguaucaa acaaaggagu agauacugua agugucggaa acacauuaua cugcgucaac     1320

aaacaagaag gacaaucccu auauguuaaa ggcgaaccua ucauuaauuu cuacgaccca     1380

cucgucuuuc cauccgacga auuugacgca ucaauuuccc aaguaaauga aaaaauaaac     1440

caaucccuug cauucauaag aaaaucagau gaacuauuac acaacguaaa cgcaggcaaa     1500

ucaacaacaa auauaaugau cacaacaaua auaaucguaa uaauaguaau ccuacucuca     1560

cuaauagcag uaggcuuacu auuauauugc aaagccagau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3095
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3095
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuucuua uccuaaaagc gaacgccaua accacaaucc uaacagcagu caccuucugu      120

uucgccucag gacaaaacau caccgaggaa uuuuaccaau ccacauguag cgcugucuca      180

aaaggcuacc ucggcgcccu ccgaaccggc ugguacacau ccguaauaac gaucgaacuc      240

uccaacauaa aagaaaauaa augcaacggc accgacgcca aagucaaacu uaucaaacaa      300

gaacuagaca aauacaaaaa cgccgucacc gaccuccagc uccucaugca auccacccca      360

gcaacaggcu ccggaagcgc aaucugcuca ggcgucgccg uaugcaaagu acuccaccuc      420

gaaggagaag ucaacaaaau caaauccgcc cuccuaucca caaacaaagc aguugucuca      480

cucuccaacg ggguaagcgu acugaccuuc aaaguccuag accucaaaaa cuacaucgau      540

aaacaacucc uuccaauccu caacaaacaa ucaugcucua uccccaacau cgaaaccgua      600

aucgaauuuc aacaaaaaaa caaccgccua cuugaaauca cacgcgaauu uagcgucaac      660

gcaggaguaa caacacccgu guccacauau augcucacga acagcgaacu acuaucccug      720

auuaacgaca ugcccaucac caacgaccaa aaaaaacuaa ugagcaacaa cguacaaauc      780

guccgccaac aaagcuacuc uauaaugugc aucaucaagg aagaaguccu agccuacguc      840

guccaauuac cacucuacgg cgucaucgac acacccugcu ggaaacucca uacauccccc      900

cucugcacca ccaacaccaa agaagggucc aacauaugcc ucacucgcac agaccgcggc      960

ugguacugcg acaacgcugg cagcgucagc uucuuccccc aggccgaaac cugcaaaguc     1020

caauccaaca gagucuucug cgacaccaug aacucgcuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacauauu caaccccaaa uacgacugca aaaucaugac cuccaaaacc     1140

gacgucagcu caucagucau cacaucccuc ggggccaucg ucuccugcua cggcaaaacc     1200

aagugcaccg ccucaaacaa aaaccgcggc auuaucaaaa cauucuccaa cggcugcgac     1260

uacgucucca acaaaggcgu cgacacaguc uccgucggua acacccucua cugcguaaau     1320

aaacaagaag gccaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccu     1380

cucgucuucc ccuccgacga auuugacgcc ucaaucagcc aaguuaacga aaaaaucaac     1440

caaucacucg ccuucauccg caaauccgac gaacuccucc acaacguuaa cgccggcaaa     1500

ucuaccacga acaucaugau caccaccaua aucaucguaa uuaucguaau acuccuaucc     1560

cucauagcag uaggccuccu acucuacugc aaagcccguu aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3096
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3096
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3097
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3097
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug gucagccucu      480

ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug agccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac cggggcuggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag gucaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc gucaacaagc     1320

aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac gacccccugg     1380

uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3098
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3098
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3099
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3099
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugacc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuaua uguucaggcg uggcagucug caagguguug caccucgagg      420

gugagguuaa caaaaucaag agcgcccugc ugaguacgaa uaaagcugug gucucccucu      480

cuaacggggu gagcguauua acuuuuaagg uucuggaucu uaagaauuac auugacaaac      540

aauugcugcc uauccuaaac aagcaguccu guucaauucc aaauaucgaa accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuagu gucaacgccg      660

gagugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug ucccucauca      720

acgauaugcc cauuacgaac gaccaaaaga aacugauguc aaauaacguc cagaucguuc      780

gccagcagag cuacaguauc augugcauua uaaaggaaga gguguuagcg uauguagugc      840

aacugccucu cuacggcguc aucgauacuc cauguuggaa acuucauaca ucuccccugu      900

gcaccacuaa uacaaaggaa ggcuccaaca uuuguuugac ccgaacggac cguggguggu      960

acugcgauaa ugcaggaagc gugucguucu uuccucaggc cgagaccugu aagguucagu     1020

cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa gucaaucucu     1080

gcaaugugga uaucuuuaac cccaaauaug acuguaagau aaugaccagu aaaacagaug     1140

uaagcuccuc uguuauuacu agccugggug cuaucguguc augcuacggc aagaccaaau     1200

guacagccag uaauaagaac agggggauca uuaagaccuu cuccaaugga ugcgacuaug     1260

ucagcaacaa aggcguggac acugucucug uggguaauac gcuuuacugu guuaacaagc     1320

aagaggggca gucacuguau gugaaaggag agccuaucau uaacuuuuac gauccauugg     1380

uauucccgag ugacgaauuu gaugcaagca uaucccaggu caaugagaag aucaaccagu     1440

cucucgcuuu cauucggaaa ucggacgaac uguuacacaa ugugaacgcc ggcaagagca     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaucccuca     1560

ucgcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3100
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3100
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3101
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3101
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggacc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauu uguagcgggg ucgccgugug caagguucuc caccuggagg      420

gagaggugaa caaaaucaag uccgcgcuuc ugagcaccaa uaaagccguc gugucucucu      480

ccaacggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac auugacaaac      540

aacuccugcc uauccugaac aagcagucuu guuccauucc gaauaucgaa accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc gugaacgcug      660

gcgucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc agccugauca      720

acgauaugcc uauuaccaac gaccaaaaga aacuuauguc caauaacgug cagaucguga      780

gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuggcc uaugugguuc      840

aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg agcccccucu      900

gcaccacaaa uaccaaggaa ggauccaaca ucugucugac acggaccgac cgcggcuggu      960

acugcgauaa ugcugggucu gucuccuucu uuccucaggc cgagacgugu aaggugcaga     1020

gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa gugaaucucu     1080

gcaaugucga uauuuuuaac cccaaauaug acuguaagau caugaccucc aaaacagaug     1140

ugucuagcuc cgucauuacc agccugggag cgaucguguc uugcuacggc aagacaaaau     1200

guacggccuc caauaagaac cgggggauua ucaagaccuu cagcaaugga ugcgacuaug     1260

uuucuaacaa aggcguggac acagucuccg ugggcaauac ccuuuacugu guuaacaagc     1320

aagaggggca gagccuguau gugaaaggag agccuaucau uaacuuuuac gauccccucg     1380

ucuucccuuc cgacgaauuu gaugcuucua ucagccaggu gaaugagaag auuaaccagu     1440

cccuggccuu cauccgcaaa ucugacgaac ugcuccacaa ugugaacgcu ggcaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucccuga     1560

ucgccguggg gcuccugcug uauugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3102
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3102
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccuaauacu uaaagccaau gcaauaacca caauacuaac agcaguaaca uucugcuuug      120

caucaggaca aaacauaaca gaagaauuuu accaaucaac auguucagca guaagcaaag      180

gauaccuagg agccuuacgc acagguuggu acacuuccgu aauaacaaua gaacucucaa      240

auauaaaaga aaacaaaugc aacggaaccg augcaaaagu aaaacuaaua aaacaagaau      300

uagacaaaua caaaaacgca guaacagacc uacaauuacu uaugcaauca acacccgcaa      360

caggauccgg cucagcaauc uguucaggag uagcaguaug caaaguucuc caccuagaag      420

gcgaaguaaa caaaauaaaa ucagcccuau uaucuaccaa uaaagcagua guaucacuau      480

caaauggagu aucuguccua accuucaaag uacuugaccu aaaaaauuac aucgacaaac      540

aauuacuacc aauacuuaac aaacaaucau guucaauacc aaacauugaa acaguaauag      600

aauuucaaca aaaaaauaac agauuauuag aaauaacccg cgaauuuuca guuaacgcag      660

gaguaacaac accaguaucc acauacaugu uaacaaauuc agaacucuua ucacuuauaa      720

acgacaugcc cauaacaaac gaccaaaaaa aacucauguc uaacaauguu caaauaguuc      780

gacaacaauc auacuccaua augugcauaa uaaaagaaga aguucuagca uauguuguac      840

aacucccacu cuaugguguu auagacacac caugcuggaa acuacauaca agccccuuau      900

gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac ccgcacagac agaggcuggu      960

auugcgauaa cgcagguuca guaucauucu uuccacaagc agaaacuugc aaaguccaau     1020

ccaauagagu cuucugcgac acuaugaacu cacucacacu cccaucugaa gucaauuuau     1080

guaacgucga uaucuucaac ccaaaauacg acugcaaaau aaugaccuca aaaacagacg     1140

uaagcucauc agucauaacu ucucuaggcg caaucgucuc auguuacggc aaaacaaaau     1200

guaccgcauc aaacaaaaau cgagguauaa uaaaaaccuu uucuaacggc ugcgacuacg     1260

uaucaaacaa aggaguagau acuguaagug ucggaaacac auuauacugc gucaacaaac     1320

aagaaggaca aucccuauau guuaaaggcg aaccuaucau uaauuucuac gacccacucg     1380

ucuuuccauc cgacgaauuu gacgcaucaa uuucccaagu aaaugaaaaa auaaaccaau     1440

cccuugcauu cauaagaaaa ucagaugaac uauuacacaa cguaaacgca ggcaaaucaa     1500

caacaaauau aaugaucaca acaauaauaa ucguaauaau aguaauccua cucucacuaa     1560

uagcaguagg cuuacuauua uauugcaaag ccagauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3103
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3103
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uucuuauccu aaaagcgaac gccauaacca caauccuaac agcagucacc uucuguuucg      120

ccucaggaca aaacaucacc gaggaauuuu accaauccac auguagcgcu gucucaaaag      180

gcuaccucgg cgcccuccga accggcuggu acacauccgu aauaacgauc gaacucucca      240

acauaaaaga aaauaaaugc aacggcaccg acgccaaagu caaacuuauc aaacaagaac      300

uagacaaaua caaaaacgcc gucaccgacc uccagcuccu caugcaaucc accccagcaa      360

caggcuccgg aagcgcaauc ugcucaggcg ucgccguaug caaaguacuc caccucgaag      420

gagaagucaa caaaaucaaa uccgcccucc uauccacaaa caaagcaguu gucucacucu      480

ccaacggggu aagcguacug accuucaaag uccuagaccu caaaaacuac aucgauaaac      540

aacuccuucc aauccucaac aaacaaucau gcucuauccc caacaucgaa accguaaucg      600

aauuucaaca aaaaaacaac cgccuacuug aaaucacacg cgaauuuagc gucaacgcag      660

gaguaacaac acccgugucc acauauaugc ucacgaacag cgaacuacua ucccugauua      720

acgacaugcc caucaccaac gaccaaaaaa aacuaaugag caacaacgua caaaucgucc      780

gccaacaaag cuacucuaua augugcauca ucaaggaaga aguccuagcc uacgucgucc      840

aauuaccacu cuacggcguc aucgacacac ccugcuggaa acuccauaca uccccccucu      900

gcaccaccaa caccaaagaa ggguccaaca uaugccucac ucgcacagac cgcggcuggu      960

acugcgacaa cgcuggcagc gucagcuucu ucccccaggc cgaaaccugc aaaguccaau     1020

ccaacagagu cuucugcgac accaugaacu cgcucacccu ccccuccgag gucaaccucu     1080

gcaacgucga cauauucaac cccaaauacg acugcaaaau caugaccucc aaaaccgacg     1140

ucagcucauc agucaucaca ucccucgggg ccaucgucuc cugcuacggc aaaaccaagu     1200

gcaccgccuc aaacaaaaac cgcggcauua ucaaaacauu cuccaacggc ugcgacuacg     1260

ucuccaacaa aggcgucgac acagucuccg ucgguaacac ccucuacugc guaaauaaac     1320

aagaaggcca aucccucuac gucaaaggcg aacccaucau caacuucuac gacccucucg     1380

ucuuccccuc cgacgaauuu gacgccucaa ucagccaagu uaacgaaaaa aucaaccaau     1440

cacucgccuu cauccgcaaa uccgacgaac uccuccacaa cguuaacgcc ggcaaaucua     1500

ccacgaacau caugaucacc accauaauca ucguaauuau cguaauacuc cuaucccuca     1560

uagcaguagg ccuccuacuc uacugcaaag cccguuaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3104
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1) R6773

<400>  3104
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3105
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt1)

<400>  3105
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucugcuccgg cguggccgug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcgcu gcuguccacc      420

aacaaggccg uggucagccu cuccaacggc gugagcgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcaguc cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcucaccaac      660

uccgagcugc ugagccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccg cuguacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggguccaa caucugccug      900

acccgcaccg accggggcug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cucccguccg aggucaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccucuacu gcgucaacaa gcaggagggc cagagccugu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccccu gguguucccg agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cgggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug gggcuccugc uguacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3106
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt2)

<400>  3106
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3107
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt3)

<400>  3107
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga ccugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua uauguucagg cguggcaguc      360

ugcaaggugu ugcaccucga gggugagguu aacaaaauca agagcgcccu gcugaguacg      420

aauaaagcug uggucucccu cucuaacggg gugagcguau uaacuuuuaa gguucuggau      480

cuuaagaauu acauugacaa acaauugcug ccuauccuaa acaagcaguc cuguucaauu      540

ccaaauaucg aaaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuua gugucaacgc cggagugacu accccgguga gcacauauau gcuuaccaau      660

ucugagcugu ugucccucau caacgauaug cccauuacga acgaccaaaa gaaacugaug      720

ucaaauaacg uccagaucgu ucgccagcag agcuacagua ucaugugcau uauaaaggaa      780

gagguguuag cguauguagu gcaacugccu cucuacggcg ucaucgauac uccauguugg      840

aaacuucaua caucuccccu gugcaccacu aauacaaagg aaggcuccaa cauuuguuug      900

acccgaacgg accgugggug guacugcgau aaugcaggaa gcgugucguu cuuuccucag      960

gccgagaccu guaagguuca gucuaacaga guguucugcg acacaaugaa cucccuaacu     1020

cugccaucag aagucaaucu cugcaaugug gauaucuuua accccaaaua ugacuguaag     1080

auaaugacca guaaaacaga uguaagcucc ucuguuauua cuagccuggg ugcuaucgug     1140

ucaugcuacg gcaagaccaa auguacagcc aguaauaaga acagggggau cauuaagacc     1200

uucuccaaug gaugcgacua ugucagcaac aaaggcgugg acacugucuc uguggguaau     1260

acgcuuuacu guguuaacaa gcaagagggg cagucacugu augugaaagg agagccuauc     1320

auuaacuuuu acgauccauu gguauucccg agugacgaau uugaugcaag cauaucccag     1380

gucaaugaga agaucaacca gucucucgcu uucauucgga aaucggacga acuguuacac     1440

aaugugaacg ccggcaagag cacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaucccu caucgcgguc ggccugcuuu uguauugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3108
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt4)

<400>  3108
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3109
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt5)

<400>  3109
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaauaaau gcaacgggac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga ccuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua uuuguagcgg ggucgccgug      360

ugcaagguuc uccaccugga gggagaggug aacaaaauca aguccgcgcu ucugagcacc      420

aauaaagccg ucgugucucu cuccaacggc guuagcgugc ugacauuuaa gguccuugau      480

cugaagaauu acauugacaa acaacuccug ccuauccuga acaagcaguc uuguuccauu      540

ccgaauaucg aaaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuua gcgugaacgc uggcgucaca acccccguuu cuacauauau gcuuaccaau      660

uccgagcugc ucagccugau caacgauaug ccuauuacca acgaccaaaa gaaacuuaug      720

uccaauaacg ugcagaucgu gagacagcag ucuuacagca uuaugugcau cauuaaggaa      780

gagguccugg ccuauguggu ucaacucccc cuguacgggg ugaucgauac accuuguugg      840

aaacugcaua cgagcccccu cugcaccaca aauaccaagg aaggauccaa caucugucug      900

acacggaccg accgcggcug guacugcgau aaugcugggu cugucuccuu cuuuccucag      960

gccgagacgu guaaggugca gagcaacaga guuuucugcg acacaaugaa cucucuuacc     1020

cugccgagcg aagugaaucu cugcaauguc gauauuuuua accccaaaua ugacuguaag     1080

aucaugaccu ccaaaacaga ugugucuagc uccgucauua ccagccuggg agcgaucgug     1140

ucuugcuacg gcaagacaaa auguacggcc uccaauaaga accgggggau uaucaagacc     1200

uucagcaaug gaugcgacua uguuucuaac aaaggcgugg acacagucuc cgugggcaau     1260

acccuuuacu guguuaacaa gcaagagggg cagagccugu augugaaagg agagccuauc     1320

auuaacuuuu acgauccccu cgucuucccu uccgacgaau uugaugcuuc uaucagccag     1380

gugaaugaga agauuaacca gucccuggcc uucauccgca aaucugacga acugcuccac     1440

aaugugaacg cuggcaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucccu gaucgccgug gggcuccugc uguauugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3110
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt6)

<400>  3110
gggagaaagc uuaccaugga acuccuaaua cuuaaagcca augcaauaac cacaauacua       60

acagcaguaa cauucugcuu ugcaucagga caaaacauaa cagaagaauu uuaccaauca      120

acauguucag caguaagcaa aggauaccua ggagccuuac gcacagguug guacacuucc      180

guaauaacaa uagaacucuc aaauauaaaa gaaaacaaau gcaacggaac cgaugcaaaa      240

guaaaacuaa uaaaacaaga auuagacaaa uacaaaaacg caguaacaga ccuacaauua      300

cuuaugcaau caacacccgc aacaggaucc ggcucagcaa ucuguucagg aguagcagua      360

ugcaaaguuc uccaccuaga aggcgaagua aacaaaauaa aaucagcccu auuaucuacc      420

aauaaagcag uaguaucacu aucaaaugga guaucugucc uaaccuucaa aguacuugac      480

cuaaaaaauu acaucgacaa acaauuacua ccaauacuua acaaacaauc auguucaaua      540

ccaaacauug aaacaguaau agaauuucaa caaaaaaaua acagauuauu agaaauaacc      600

cgcgaauuuu caguuaacgc aggaguaaca acaccaguau ccacauacau guuaacaaau      660

ucagaacucu uaucacuuau aaacgacaug cccauaacaa acgaccaaaa aaaacucaug      720

ucuaacaaug uucaaauagu ucgacaacaa ucauacucca uaaugugcau aauaaaagaa      780

gaaguucuag cauauguugu acaacuccca cucuauggug uuauagacac accaugcugg      840

aaacuacaua caagccccuu augcacuaca aacacaaaag aaggcucuaa uauaugucua      900

acccgcacag acagaggcug guauugcgau aacgcagguu caguaucauu cuuuccacaa      960

gcagaaacuu gcaaagucca auccaauaga gucuucugcg acacuaugaa cucacucaca     1020

cucccaucug aagucaauuu auguaacguc gauaucuuca acccaaaaua cgacugcaaa     1080

auaaugaccu caaaaacaga cguaagcuca ucagucauaa cuucucuagg cgcaaucguc     1140

ucauguuacg gcaaaacaaa auguaccgca ucaaacaaaa aucgagguau aauaaaaacc     1200

uuuucuaacg gcugcgacua cguaucaaac aaaggaguag auacuguaag ugucggaaac     1260

acauuauacu gcgucaacaa acaagaagga caaucccuau auguuaaagg cgaaccuauc     1320

auuaauuucu acgacccacu cgucuuucca uccgacgaau uugacgcauc aauuucccaa     1380

guaaaugaaa aaauaaacca aucccuugca uucauaagaa aaucagauga acuauuacac     1440

aacguaaacg caggcaaauc aacaacaaau auaaugauca caacaauaau aaucguaaua     1500

auaguaaucc uacucucacu aauagcagua ggcuuacuau uauauugcaa agccagauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3111
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut2 (opt11)

<400>  3111
gggagaaagc uuaccaugga acuucuuauc cuaaaagcga acgccauaac cacaauccua       60

acagcaguca ccuucuguuu cgccucagga caaaacauca ccgaggaauu uuaccaaucc      120

acauguagcg cugucucaaa aggcuaccuc ggcgcccucc gaaccggcug guacacaucc      180

guaauaacga ucgaacucuc caacauaaaa gaaaauaaau gcaacggcac cgacgccaaa      240

gucaaacuua ucaaacaaga acuagacaaa uacaaaaacg ccgucaccga ccuccagcuc      300

cucaugcaau ccaccccagc aacaggcucc ggaagcgcaa ucugcucagg cgucgccgua      360

ugcaaaguac uccaccucga aggagaaguc aacaaaauca aauccgcccu ccuauccaca      420

aacaaagcag uugucucacu cuccaacggg guaagcguac ugaccuucaa aguccuagac      480

cucaaaaacu acaucgauaa acaacuccuu ccaauccuca acaaacaauc augcucuauc      540

cccaacaucg aaaccguaau cgaauuucaa caaaaaaaca accgccuacu ugaaaucaca      600

cgcgaauuua gcgucaacgc aggaguaaca acacccgugu ccacauauau gcucacgaac      660

agcgaacuac uaucccugau uaacgacaug cccaucacca acgaccaaaa aaaacuaaug      720

agcaacaacg uacaaaucgu ccgccaacaa agcuacucua uaaugugcau caucaaggaa      780

gaaguccuag ccuacgucgu ccaauuacca cucuacggcg ucaucgacac acccugcugg      840

aaacuccaua cauccccccu cugcaccacc aacaccaaag aaggguccaa cauaugccuc      900

acucgcacag accgcggcug guacugcgac aacgcuggca gcgucagcuu cuucccccag      960

gccgaaaccu gcaaagucca auccaacaga gucuucugcg acaccaugaa cucgcucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacauauuca accccaaaua cgacugcaaa     1080

aucaugaccu ccaaaaccga cgucagcuca ucagucauca caucccucgg ggccaucguc     1140

uccugcuacg gcaaaaccaa gugcaccgcc ucaaacaaaa accgcggcau uaucaaaaca     1200

uucuccaacg gcugcgacua cgucuccaac aaaggcgucg acacagucuc cgucgguaac     1260

acccucuacu gcguaaauaa acaagaaggc caaucccucu acgucaaagg cgaacccauc     1320

aucaacuucu acgacccucu cgucuucccc uccgacgaau uugacgccuc aaucagccaa     1380

guuaacgaaa aaaucaacca aucacucgcc uucauccgca aauccgacga acuccuccac     1440

aacguuaacg ccggcaaauc uaccacgaac aucaugauca ccaccauaau caucguaauu     1500

aucguaauac uccuaucccu cauagcagua ggccuccuac ucuacugcaa agcccguuaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3112
<211>  535
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3112

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly Ile 
        515                 520                 525             


Asn Asn Ile Ala Phe Ser Asn 
    530                 535 


<210>  3113
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3113
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1560

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacuga                  1608


<210>  3114
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3114
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucugc uccggcgugg ccgugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcgcugcugu ccaccaacaa ggccgugguc      420

agccucucca acggcgugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccgcugua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      900

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu cuacugcguc     1260

aacaagcagg agggccagag ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguccacccc cgugacccug     1560

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  3115
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3115
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1560

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacuga                  1608


<210>  3116
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3116
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagau caaaugcaau ggcaccgacg ccaaggugaa acuaauaaag      240

caggaacucg auaaguauaa aaacgcagua acugaccugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuaucugu ucaggcgugg cagucugcaa gguguugcac      360

cucgagggug agguuaauaa aauuaagagc gcccugcuga guacgaacaa agcugugguc      420

ucccucucua auggggugag cguauuaacu uuuaagguuc uggaucuuaa gaacuacauc      480

gacaaacaau ugcugccuau ucuaaauaag caguccuguu caaucccaaa cauagaaacc      540

gugauugagu uccagcagaa aaauaacagg cuccuggaaa ucacacggga guuuaguguc      600

aaugccggag ugacuacccc ggugagcaca uauaugcuua ccaacucuga gcuguugucc      660

cucauuaaug auaugcccau cacgaacgac caaaagaaac ugaugucaaa caauguccag      720

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcguau      780

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      840

ccccugugca ccacuaacac aaaggaaggc uccaauaucu guuugacccg aacggaccgu      900

gggugguacu gcgauaacgc aggaagcgug ucguucuuuc cucaggccga gaccuguaag      960

guucagucua auagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1020

aaucucugca acguggauau auuuaauccc aaauaugacu guaagauuau gaccaguaaa     1080

acagauguaa gcuccucugu uaucacuagc cugggugcua ucgugucaug cuacggcaag     1140

accaaaugua cagccaguaa caagaauagg gggauuauca agaccuucuc caacggaugc     1200

gacuauguca gcaauaaagg cguggacacu gucucugugg guaacacgcu uuacuguguu     1260

aauaagcaag aggggcaguc acuguaugug aaaggagagc cuauuauaaa cuuuuacgau     1320

ccauugguau ucccgaguga cgaauuugau gcaagcaucu cccaggucaa cgagaagauu     1380

aaucagucuc ucgcuuucau ccggaaaucg gacgaacugu uacacaacgu gaaugccggc     1440

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1500

ucccucauag cggucggccu gcuuuuguau ugcaaggccc gcucaacacc cgugacccug     1560

aguaaagauc aacucucugg gaucaauaac auugcauuca gcaauuga                  1608


<210>  3117
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3117
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1560

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  3118
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3118
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagau caaaugcaau gggaccgacg ccaaggugaa acuuauuaag      240

caggaacugg auaaguauaa aaacgcugug acggaccucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuaucugu agcggggucg ccgugugcaa gguucuccac      360

cuggagggag aggugaauaa aauuaagucc gcgcuucuga gcaccaacaa agccgucgug      420

ucucucucca auggcguuag cgugcugaca uuuaaggucc uugaucugaa gaacuacauc      480

gacaaacaac uccugccuau ucugaauaag cagucuuguu ccaucccgaa cauugaaacc      540

gugaucgagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuagcgug      600

aaugcuggcg ucacaacccc cguuucuaca uauaugcuua ccaacuccga gcugcucagc      660

cugauuaaug auaugccuau caccaacgac caaaagaaac uuauguccaa caaugugcag      720

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggccuau      780

gugguucaac ucccccugua cggggugauc gauacaccuu guuggaaacu gcauacgagc      840

ccccucugca ccacaaacac caaggaagga uccaauauuu gucugacacg gaccgaccgc      900

ggcugguacu gcgauaacgc ugggucuguc uccuucuuuc cucaggccga gacguguaag      960

gugcagagca auagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1020

aaucucugca acgucgauau cuuuaauccc aaauaugacu guaagauuau gaccuccaaa     1080

acagaugugu cuagcuccgu caucaccagc cugggagcga uugugucuug cuacggcaag     1140

acaaaaugua cggccuccaa caagaaucgg gggaucauca agaccuucag caacggaugc     1200

gacuauguuu cuaauaaagg cguggacaca gucuccgugg gcaacacccu uuacuguguu     1260

aauaagcaag aggggcagag ccuguaugug aaaggagagc cuauuaucaa cuuuuacgau     1320

ccccucgucu ucccuuccga cgaauuugau gcuucuauua gccaggugaa cgagaagauc     1380

aaucaguccc uggccuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugcuggc     1440

aagagcacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1500

ucccugauug ccguggggcu ccugcuguau ugcaaggcca gaagcacacc cgugacccuu     1560

ucuaaagauc aacucuccgg aaucaauaac aucgcuuuca gcaauuga                  1608


<210>  3119
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3119
auggaauuac ucauacuaaa agccaaugcc auaaccacua uucuaacagc aguaacauuc       60

uguuucgccu caggacaaaa cauaacagaa gaauuuuauc aauccaccug uuccgcaguc      120

ucgaaaggcu accuuggcgc acuaagaacc ggaugguaua caucaguaau aaccauugaa      180

cuaucaaaua ucaaagaaau aaaaugcaac ggaacugacg caaaagucaa acuaauaaaa      240

caagaauuag acaaauacaa aaacgccguu acagacuuac aacuacuaau gcaaucaacu      300

ccagcaacag gaucaggauc ugcuauaugc ucaggugucg ccguauguaa aguguuacac      360

cucgaaggcg aaguaaacaa aauaaaauca gcacuacuau ccacaaauaa agcaguagua      420

ucacuaucca augguguauc aguacucaca uucaaaguac uagacuuaaa aaauuauaua      480

gauaaacaau uacuaccaau auuaaacaaa caaucaugcu caauaccaaa cauagaaacc      540

gucauugaau uucaacaaaa aaacaaucga cuucuugaaa uaacacgaga auuuucagua      600

aaugccggag uaacaacccc agucucaaca uacauguuaa ccaacucuga acuccuaagc      660

cuaaucaacg acaugcccau aacuaacgac caaaaaaaac uaauguccaa uaauguccaa      720

auaguaagac aacaauccua cucaauaaug ugcauuauaa aagaagaagu ccucgccuau      780

guaguacaac uacccuuaua cggaguaauu gacacaccau guuggaaacu acauacauca      840

ccacuaugca ccacuaacac aaaagaaggc uccaacauau gccuaacccg aacagaucgc      900

ggaugguauu gcgacaacgc aggaagugua uccuucuuuc cacaagcaga aacaugcaaa      960

guacaaucca acagaguauu cugugacacc augaacucuc uaacacuacc uuccgaagua     1020

aauuuaugca acguagacau auuuaauccc aaauacgacu guaaaauaau gaccucaaaa     1080

acugaugucu caucaucagu cauuacauca cucggagcaa uagucaguug cuauggaaaa     1140

accaaaugca cagcuaguaa caaaaacagg gguauaauaa aaacauuuuc aaacggaugc     1200

gauuacguau caaauaaagg aguagacacc guauccguag gaaauacucu cuacugcgua     1260

aacaaacaag aaggacaauc ccuauacgua aaaggcgaac caaucauuaa cuuuuacgac     1320

ccacuuguau uuccaucaga cgaauuugau gccucaauau cccaagucaa ugaaaaaaua     1380

aaccaaaguc uagcauucau ccgaaaauca gaugaacuuu uacacaacgu aaacgccgga     1440

aaaucaacaa caaacaucau gaucacaaca aucaucauag uaauaauagu uauacuacuu     1500

uccuuaauag cagucggccu acuacucuac ugcaaagcac gauccacacc aguaaccuua     1560

ucuaaagacc aacucucagg cauaaacaac auagcauucu caaacuaa                  1608


<210>  3120
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut3

<400>  3120
auggaacucc ucauccuuaa agcaaacgcc aucacaacca uccucacagc agucacuuuc       60

ugcuucgcau ccggacaaaa caucacagaa gaguucuauc aauccacgug cuccgcaguu      120

uccaaaggau accuuggagc cuuacgaacc ggcugguaca ccuccgucau caccauagaa      180

cucagcaaca ucaaagaaau caaaugcaac ggaaccgacg caaaagucaa acucaucaaa      240

caagaacuag acaaauacaa aaacgcaguc accgaccucc aacuacucau gcaaucaacc      300

cccgcaaccg gcuccggcuc cgccaucugc uccggaguag ccguaugcaa aguccuccac      360

cucgaaggcg aaguuaacaa gaucaagucc gcacuccuau caaccaacaa agcagucguc      420

ucccuaucca acggcgucuc cguauuaaca uucaaagucc ucgaccucaa aaacuacaua      480

gacaaacagc uacuccccau ccuaaacaaa caauccugcu ccauccccaa caucgaaacu      540

gucaucgagu uccaacagaa aaacaaccgc cuccuagaaa ucacccgaga guucuccgua      600

aacgccggcg ucacuacccc cgucucuacc uauaugcuaa ccaacucuga acuccuaucc      660

cuaaucaacg auaugcccau aacuaacgac caaaagaaac uuauguccaa caacguacaa      720

auaguccggc aacaaucaua cucuaucaug ugcaucauca aagaagaagu acuugccuac      780

guuguccaac ucccacuaua cggcgucaua gacacuccau gcuggaaacu ucacaccuca      840

ccccucugca ccacuaacac uaaagaaggc ucuaacaucu gccuuacccg caccgaccgc      900

ggaugguacu gcgacaacgc aggcucaguu agcuucuucc cacaagccga aaccugcaaa      960

guccagucaa accgugucuu cugcgauacc augaacucgc ucacccuccc uuccgaaguc     1020

aaccucugca acgucgacau cuucaacccc aaauacgacu gcaaaaucau gaccucaaaa     1080

accgacguau cuucuuccgu caucaccucc cucggcgcca ucguauccug cuacggcaaa     1140

accaaaugca cugcaucaaa caaaaaccga ggcaucauca aaaccuucuc gaacggaugc     1200

gacuacguau ccaacaaggg cgucgacaca gucuccguug guaacacccu cuacugcguc     1260

aacaaacaag aaggccaauc ccuauacgua aaaggcgaac ccaucaucaa cuucuacgac     1320

ccccucgucu uccccaguga cgaauuugac gccuccaucu cccaagucaa cgaaaagauc     1380

aaccaauccc uugccuucau acgcaaaucc gacgaacucc uacacaacgu uaacgccgga     1440

aaaucaacaa ccaacaucau gaucacaacc aucauaaucg ucauaaucgu cauacuccuc     1500

ucccucauag ccgucggccu gcuauuguac uguaaagccc gcuccacacc agucacacuu     1560

ucaaaagacc aacucuccgg gaucaacaac aucgccuucu ccaacuaa                  1608


<210>  3121
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3121
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3122
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3122
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3123
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3123
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3124
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3124
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau caauaacauu gcauucagca     1680

auugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3125
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3125
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3126
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3126
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau caauaacauc gcuuucagca     1680

auugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3127
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3127
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacuaaaagc caaugccaua accacuauuc      120

uaacagcagu aacauucugu uucgccucag gacaaaacau aacagaagaa uuuuaucaau      180

ccaccuguuc cgcagucucg aaaggcuacc uuggcgcacu aagaaccgga ugguauacau      240

caguaauaac cauugaacua ucaaauauca aagaaauaaa augcaacgga acugacgcaa      300

aagucaaacu aauaaaacaa gaauuagaca aauacaaaaa cgccguuaca gacuuacaac      360

uacuaaugca aucaacucca gcaacaggau caggaucugc uauaugcuca ggugucgccg      420

uauguaaagu guuacaccuc gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca      480

caaauaaagc aguaguauca cuauccaaug guguaucagu acucacauuc aaaguacuag      540

acuuaaaaaa uuauauagau aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa      600

uaccaaacau agaaaccguc auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa      660

cacgagaauu uucaguaaau gccggaguaa caaccccagu cucaacauac auguuaacca      720

acucugaacu ccuaagccua aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa      780

uguccaauaa uguccaaaua guaagacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu cgccuaugua guacaacuac ccuuauacgg aguaauugac acaccauguu      900

ggaaacuaca uacaucacca cuaugcacca cuaacacaaa agaaggcucc aacauaugcc      960

uaacccgaac agaucgcgga ugguauugcg acaacgcagg aaguguaucc uucuuuccac     1020

aagcagaaac augcaaagua caauccaaca gaguauucug ugacaccaug aacucucuaa     1080

cacuaccuuc cgaaguaaau uuaugcaacg uagacauauu uaaucccaaa uacgacugua     1140

aaauaaugac cucaaaaacu gaugucucau caucagucau uacaucacuc ggagcaauag     1200

ucaguugcua uggaaaaacc aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa     1260

cauuuucaaa cggaugcgau uacguaucaa auaaaggagu agacaccgua uccguaggaa     1320

auacucucua cugcguaaac aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa     1380

ucauuaacuu uuacgaccca cuuguauuuc caucagacga auuugaugcc ucaauauccc     1440

aagucaauga aaaaauaaac caaagucuag cauucauccg aaaaucagau gaacuuuuac     1500

acaacguaaa cgccggaaaa ucaacaacaa acaucaugau cacaacaauc aucauaguaa     1560

uaauaguuau acuacuuucc uuaauagcag ucggccuacu acucuacugc aaagcacgau     1620

ccacaccagu aaccuuaucu aaagaccaac ucucaggcau aaacaacaua gcauucucaa     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3128
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3128
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc aaacgccauc acaaccaucc      120

ucacagcagu cacuuucugc uucgcauccg gacaaaacau cacagaagag uucuaucaau      180

ccacgugcuc cgcaguuucc aaaggauacc uuggagccuu acgaaccggc ugguacaccu      240

ccgucaucac cauagaacuc agcaacauca aagaaaucaa augcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa cgcagucacc gaccuccaac      360

uacucaugca aucaaccccc gcaaccggcu ccggcuccgc caucugcucc ggaguagccg      420

uaugcaaagu ccuccaccuc gaaggcgaag uuaacaagau caaguccgca cuccuaucaa      480

ccaacaaagc agucgucucc cuauccaacg gcgucuccgu auuaacauuc aaaguccucg      540

accucaaaaa cuacauagac aaacagcuac uccccauccu aaacaaacaa uccugcucca      600

uccccaacau cgaaacuguc aucgaguucc aacagaaaaa caaccgccuc cuagaaauca      660

cccgagaguu cuccguaaac gccggcguca cuacccccgu cucuaccuau augcuaacca      720

acucugaacu ccuaucccua aucaacgaua ugcccauaac uaacgaccaa aagaaacuua      780

uguccaacaa cguacaaaua guccggcaac aaucauacuc uaucaugugc aucaucaaag      840

aagaaguacu ugccuacguu guccaacucc cacuauacgg cgucauagac acuccaugcu      900

ggaaacuuca caccucaccc cucugcacca cuaacacuaa agaaggcucu aacaucugcc      960

uuacccgcac cgaccgcgga ugguacugcg acaacgcagg cucaguuagc uucuucccac     1020

aagccgaaac cugcaaaguc cagucaaacc gugucuucug cgauaccaug aacucgcuca     1080

cccucccuuc cgaagucaac cucugcaacg ucgacaucuu caaccccaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacguaucuu cuuccgucau caccucccuc ggcgccaucg     1200

uauccugcua cggcaaaacc aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa     1260

ccuucucgaa cggaugcgac uacguaucca acaagggcgu cgacacaguc uccguuggua     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu auacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccagugacga auuugacgcc uccaucuccc     1440

aagucaacga aaagaucaac caaucccuug ccuucauacg caaauccgac gaacuccuac     1500

acaacguuaa cgccggaaaa ucaacaacca acaucaugau cacaaccauc auaaucguca     1560

uaaucgucau acuccucucc cucauagccg ucggccugcu auuguacugu aaagcccgcu     1620

ccacaccagu cacacuuuca aaagaccaac ucuccgggau caacaacauc gccuucucca     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3129
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3129
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3130
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3130
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3131
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3131
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3132
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3132
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggauc     1680

aauaacauug cauucagcaa uugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3133
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3133
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3134
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3134
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauc     1680

aauaacaucg cuuucagcaa uugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3135
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3135
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acuaaaagcc      120

aaugccauaa ccacuauucu aacagcagua acauucuguu ucgccucagg acaaaacaua      180

acagaagaau uuuaucaauc caccuguucc gcagucucga aaggcuaccu uggcgcacua      240

agaaccggau gguauacauc aguaauaacc auugaacuau caaauaucaa agaaauaaaa      300

ugcaacggaa cugacgcaaa agucaaacua auaaaacaag aauuagacaa auacaaaaac      360

gccguuacag acuuacaacu acuaaugcaa ucaacuccag caacaggauc aggaucugcu      420

auaugcucag gugucgccgu auguaaagug uuacaccucg aaggcgaagu aaacaaaaua      480

aaaucagcac uacuauccac aaauaaagca guaguaucac uauccaaugg uguaucagua      540

cucacauuca aaguacuaga cuuaaaaaau uauauagaua aacaauuacu accaauauua      600

aacaaacaau caugcucaau accaaacaua gaaaccguca uugaauuuca acaaaaaaac      660

aaucgacuuc uugaaauaac acgagaauuu ucaguaaaug ccggaguaac aaccccaguc      720

ucaacauaca uguuaaccaa cucugaacuc cuaagccuaa ucaacgacau gcccauaacu      780

aacgaccaaa aaaaacuaau guccaauaau guccaaauag uaagacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccuc gccuauguag uacaacuacc cuuauacgga      900

guaauugaca caccauguug gaaacuacau acaucaccac uaugcaccac uaacacaaaa      960

gaaggcucca acauaugccu aacccgaaca gaucgcggau gguauugcga caacgcagga     1020

aguguauccu ucuuuccaca agcagaaaca ugcaaaguac aauccaacag aguauucugu     1080

gacaccauga acucucuaac acuaccuucc gaaguaaauu uaugcaacgu agacauauuu     1140

aaucccaaau acgacuguaa aauaaugacc ucaaaaacug augucucauc aucagucauu     1200

acaucacucg gagcaauagu caguugcuau ggaaaaacca aaugcacagc uaguaacaaa     1260

aacaggggua uaauaaaaac auuuucaaac ggaugcgauu acguaucaaa uaaaggagua     1320

gacaccguau ccguaggaaa uacucucuac ugcguaaaca aacaagaagg acaaucccua     1380

uacguaaaag gcgaaccaau cauuaacuuu uacgacccac uuguauuucc aucagacgaa     1440

uuugaugccu caauauccca agucaaugaa aaaauaaacc aaagucuagc auucauccga     1500

aaaucagaug aacuuuuaca caacguaaac gccggaaaau caacaacaaa caucaugauc     1560

acaacaauca ucauaguaau aauaguuaua cuacuuuccu uaauagcagu cggccuacua     1620

cucuacugca aagcacgauc cacaccagua accuuaucua aagaccaacu cucaggcaua     1680

aacaacauag cauucucaaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3136
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3136
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagca      120

aacgccauca caaccauccu cacagcaguc acuuucugcu ucgcauccgg acaaaacauc      180

acagaagagu ucuaucaauc cacgugcucc gcaguuucca aaggauaccu uggagccuua      240

cgaaccggcu gguacaccuc cgucaucacc auagaacuca gcaacaucaa agaaaucaaa      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaaaaac      360

gcagucaccg accuccaacu acucaugcaa ucaacccccg caaccggcuc cggcuccgcc      420

aucugcuccg gaguagccgu augcaaaguc cuccaccucg aaggcgaagu uaacaagauc      480

aaguccgcac uccuaucaac caacaaagca gucgucuccc uauccaacgg cgucuccgua      540

uuaacauuca aaguccucga ccucaaaaac uacauagaca aacagcuacu ccccauccua      600

aacaaacaau ccugcuccau ccccaacauc gaaacuguca ucgaguucca acagaaaaac      660

aaccgccucc uagaaaucac ccgagaguuc uccguaaacg ccggcgucac uacccccguc      720

ucuaccuaua ugcuaaccaa cucugaacuc cuaucccuaa ucaacgauau gcccauaacu      780

aacgaccaaa agaaacuuau guccaacaac guacaaauag uccggcaaca aucauacucu      840

aucaugugca ucaucaaaga agaaguacuu gccuacguug uccaacuccc acuauacggc      900

gucauagaca cuccaugcug gaaacuucac accucacccc ucugcaccac uaacacuaaa      960

gaaggcucua acaucugccu uacccgcacc gaccgcggau gguacugcga caacgcaggc     1020

ucaguuagcu ucuucccaca agccgaaacc ugcaaagucc agucaaaccg ugucuucugc     1080

gauaccauga acucgcucac ccucccuucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucaaaaaccg acguaucuuc uuccgucauc     1200

accucccucg gcgccaucgu auccugcuac ggcaaaacca aaugcacugc aucaaacaaa     1260

aaccgaggca ucaucaaaac cuucucgaac ggaugcgacu acguauccaa caagggcguc     1320

gacacagucu ccguugguaa cacccucuac ugcgucaaca aacaagaagg ccaaucccua     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cagugacgaa     1440

uuugacgccu ccaucuccca agucaacgaa aagaucaacc aaucccuugc cuucauacgc     1500

aaauccgacg aacuccuaca caacguuaac gccggaaaau caacaaccaa caucaugauc     1560

acaaccauca uaaucgucau aaucgucaua cuccucuccc ucauagccgu cggccugcua     1620

uuguacugua aagcccgcuc cacaccaguc acacuuucaa aagaccaacu cuccgggauc     1680

aacaacaucg ccuucuccaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3137
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3137
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3138
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3138
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3139
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3139
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3140
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3140
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggaucaa uaacauugca uucagcaauu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3141
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3141
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3142
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3142
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaaucaa uaacaucgcu uucagcaauu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3143
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3143
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac uaaaagccaa ugccauaacc acuauucuaa cagcaguaac auucuguuuc      240

gccucaggac aaaacauaac agaagaauuu uaucaaucca ccuguuccgc agucucgaaa      300

ggcuaccuug gcgcacuaag aaccggaugg uauacaucag uaauaaccau ugaacuauca      360

aauaucaaag aaauaaaaug caacggaacu gacgcaaaag ucaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc cguuacagac uuacaacuac uaaugcaauc aacuccagca      480

acaggaucag gaucugcuau augcucaggu gucgccguau guaaaguguu acaccucgaa      540

ggcgaaguaa acaaaauaaa aucagcacua cuauccacaa auaaagcagu aguaucacua      600

uccaauggug uaucaguacu cacauucaaa guacuagacu uaaaaaauua uauagauaaa      660

caauuacuac caauauuaaa caaacaauca ugcucaauac caaacauaga aaccgucauu      720

gaauuucaac aaaaaaacaa ucgacuucuu gaaauaacac gagaauuuuc aguaaaugcc      780

ggaguaacaa ccccagucuc aacauacaug uuaaccaacu cugaacuccu aagccuaauc      840

aacgacaugc ccauaacuaa cgaccaaaaa aaacuaaugu ccaauaaugu ccaaauagua      900

agacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccucgc cuauguagua      960

caacuacccu uauacggagu aauugacaca ccauguugga aacuacauac aucaccacua     1020

ugcaccacua acacaaaaga aggcuccaac auaugccuaa cccgaacaga ucgcggaugg     1080

uauugcgaca acgcaggaag uguauccuuc uuuccacaag cagaaacaug caaaguacaa     1140

uccaacagag uauucuguga caccaugaac ucucuaacac uaccuuccga aguaaauuua     1200

ugcaacguag acauauuuaa ucccaaauac gacuguaaaa uaaugaccuc aaaaacugau     1260

gucucaucau cagucauuac aucacucgga gcaauaguca guugcuaugg aaaaaccaaa     1320

ugcacagcua guaacaaaaa cagggguaua auaaaaacau uuucaaacgg augcgauuac     1380

guaucaaaua aaggaguaga caccguaucc guaggaaaua cucucuacug cguaaacaaa     1440

caagaaggac aaucccuaua cguaaaaggc gaaccaauca uuaacuuuua cgacccacuu     1500

guauuuccau cagacgaauu ugaugccuca auaucccaag ucaaugaaaa aauaaaccaa     1560

agucuagcau ucauccgaaa aucagaugaa cuuuuacaca acguaaacgc cggaaaauca     1620

acaacaaaca ucaugaucac aacaaucauc auaguaauaa uaguuauacu acuuuccuua     1680

auagcagucg gccuacuacu cuacugcaaa gcacgaucca caccaguaac cuuaucuaaa     1740

gaccaacucu caggcauaaa caacauagca uucucaaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3144
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3144
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagcaaa cgccaucaca accauccuca cagcagucac uuucugcuuc      240

gcauccggac aaaacaucac agaagaguuc uaucaaucca cgugcuccgc aguuuccaaa      300

ggauaccuug gagccuuacg aaccggcugg uacaccuccg ucaucaccau agaacucagc      360

aacaucaaag aaaucaaaug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaacgc agucaccgac cuccaacuac ucaugcaauc aacccccgca      480

accggcuccg gcuccgccau cugcuccgga guagccguau gcaaaguccu ccaccucgaa      540

ggcgaaguua acaagaucaa guccgcacuc cuaucaacca acaaagcagu cgucucccua      600

uccaacggcg ucuccguauu aacauucaaa guccucgacc ucaaaaacua cauagacaaa      660

cagcuacucc ccauccuaaa caaacaaucc ugcuccaucc ccaacaucga aacugucauc      720

gaguuccaac agaaaaacaa ccgccuccua gaaaucaccc gagaguucuc cguaaacgcc      780

ggcgucacua cccccgucuc uaccuauaug cuaaccaacu cugaacuccu aucccuaauc      840

aacgauaugc ccauaacuaa cgaccaaaag aaacuuaugu ccaacaacgu acaaauaguc      900

cggcaacaau cauacucuau caugugcauc aucaaagaag aaguacuugc cuacguuguc      960

caacucccac uauacggcgu cauagacacu ccaugcugga aacuucacac cucaccccuc     1020

ugcaccacua acacuaaaga aggcucuaac aucugccuua cccgcaccga ccgcggaugg     1080

uacugcgaca acgcaggcuc aguuagcuuc uucccacaag ccgaaaccug caaaguccag     1140

ucaaaccgug ucuucugcga uaccaugaac ucgcucaccc ucccuuccga agucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

guaucuucuu ccgucaucac cucccucggc gccaucguau ccugcuacgg caaaaccaaa     1320

ugcacugcau caaacaaaaa ccgaggcauc aucaaaaccu ucucgaacgg augcgacuac     1380

guauccaaca agggcgucga cacagucucc guugguaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccuaua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuucccca gugacgaauu ugacgccucc aucucccaag ucaacgaaaa gaucaaccaa     1560

ucccuugccu ucauacgcaa auccgacgaa cuccuacaca acguuaacgc cggaaaauca     1620

acaaccaaca ucaugaucac aaccaucaua aucgucauaa ucgucauacu ccucucccuc     1680

auagccgucg gccugcuauu guacuguaaa gcccgcucca caccagucac acuuucaaaa     1740

gaccaacucu ccgggaucaa caacaucgcc uucuccaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3145
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3145
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3146
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3146
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3147
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3147
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3148
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3148
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggaucaau aacauugcau ucagcaauug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3149
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3149
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3150
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3150
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaaucaau aacaucgcuu ucagcaauug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3151
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3151
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu aaaagccaau gccauaacca cuauucuaac agcaguaaca      180

uucuguuucg ccucaggaca aaacauaaca gaagaauuuu aucaauccac cuguuccgca      240

gucucgaaag gcuaccuugg cgcacuaaga accggauggu auacaucagu aauaaccauu      300

gaacuaucaa auaucaaaga aauaaaaugc aacggaacug acgcaaaagu caaacuaaua      360

aaacaagaau uagacaaaua caaaaacgcc guuacagacu uacaacuacu aaugcaauca      420

acuccagcaa caggaucagg aucugcuaua ugcucaggug ucgccguaug uaaaguguua      480

caccucgaag gcgaaguaaa caaaauaaaa ucagcacuac uauccacaaa uaaagcagua      540

guaucacuau ccaauggugu aucaguacuc acauucaaag uacuagacuu aaaaaauuau      600

auagauaaac aauuacuacc aauauuaaac aaacaaucau gcucaauacc aaacauagaa      660

accgucauug aauuucaaca aaaaaacaau cgacuucuug aaauaacacg agaauuuuca      720

guaaaugccg gaguaacaac cccagucuca acauacaugu uaaccaacuc ugaacuccua      780

agccuaauca acgacaugcc cauaacuaac gaccaaaaaa aacuaauguc caauaauguc      840

caaauaguaa gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccucgcc      900

uauguaguac aacuacccuu auacggagua auugacacac cauguuggaa acuacauaca      960

ucaccacuau gcaccacuaa cacaaaagaa ggcuccaaca uaugccuaac ccgaacagau     1020

cgcggauggu auugcgacaa cgcaggaagu guauccuucu uuccacaagc agaaacaugc     1080

aaaguacaau ccaacagagu auucugugac accaugaacu cucuaacacu accuuccgaa     1140

guaaauuuau gcaacguaga cauauuuaau cccaaauacg acuguaaaau aaugaccuca     1200

aaaacugaug ucucaucauc agucauuaca ucacucggag caauagucag uugcuaugga     1260

aaaaccaaau gcacagcuag uaacaaaaac agggguauaa uaaaaacauu uucaaacgga     1320

ugcgauuacg uaucaaauaa aggaguagac accguauccg uaggaaauac ucucuacugc     1380

guaaacaaac aagaaggaca aucccuauac guaaaaggcg aaccaaucau uaacuuuuac     1440

gacccacuug uauuuccauc agacgaauuu gaugccucaa uaucccaagu caaugaaaaa     1500

auaaaccaaa gucuagcauu cauccgaaaa ucagaugaac uuuuacacaa cguaaacgcc     1560

ggaaaaucaa caacaaacau caugaucaca acaaucauca uaguaauaau aguuauacua     1620

cuuuccuuaa uagcagucgg ccuacuacuc uacugcaaag cacgauccac accaguaacc     1680

uuaucuaaag accaacucuc aggcauaaac aacauagcau ucucaaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3152
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3152
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagcaaac gccaucacaa ccauccucac agcagucacu      180

uucugcuucg cauccggaca aaacaucaca gaagaguucu aucaauccac gugcuccgca      240

guuuccaaag gauaccuugg agccuuacga accggcuggu acaccuccgu caucaccaua      300

gaacucagca acaucaaaga aaucaaaugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaacgca gucaccgacc uccaacuacu caugcaauca      420

acccccgcaa ccggcuccgg cuccgccauc ugcuccggag uagccguaug caaaguccuc      480

caccucgaag gcgaaguuaa caagaucaag uccgcacucc uaucaaccaa caaagcaguc      540

gucucccuau ccaacggcgu cuccguauua acauucaaag uccucgaccu caaaaacuac      600

auagacaaac agcuacuccc cauccuaaac aaacaauccu gcuccauccc caacaucgaa      660

acugucaucg aguuccaaca gaaaaacaac cgccuccuag aaaucacccg agaguucucc      720

guaaacgccg gcgucacuac ccccgucucu accuauaugc uaaccaacuc ugaacuccua      780

ucccuaauca acgauaugcc cauaacuaac gaccaaaaga aacuuauguc caacaacgua      840

caaauagucc ggcaacaauc auacucuauc augugcauca ucaaagaaga aguacuugcc      900

uacguugucc aacucccacu auacggcguc auagacacuc caugcuggaa acuucacacc      960

ucaccccucu gcaccacuaa cacuaaagaa ggcucuaaca ucugccuuac ccgcaccgac     1020

cgcggauggu acugcgacaa cgcaggcuca guuagcuucu ucccacaagc cgaaaccugc     1080

aaaguccagu caaaccgugu cuucugcgau accaugaacu cgcucacccu cccuuccgaa     1140

gucaaccucu gcaacgucga caucuucaac cccaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg uaucuucuuc cgucaucacc ucccucggcg ccaucguauc cugcuacggc     1260

aaaaccaaau gcacugcauc aaacaaaaac cgaggcauca ucaaaaccuu cucgaacgga     1320

ugcgacuacg uauccaacaa gggcgucgac acagucuccg uugguaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccuauac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccag ugacgaauuu gacgccucca ucucccaagu caacgaaaag     1500

aucaaccaau cccuugccuu cauacgcaaa uccgacgaac uccuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaacau caugaucaca accaucauaa ucgucauaau cgucauacuc     1620

cucucccuca uagccgucgg ccugcuauug uacuguaaag cccgcuccac accagucaca     1680

cuuucaaaag accaacucuc cgggaucaac aacaucgccu ucuccaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3153
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3153
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3154
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3154
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3155
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3155
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3156
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3156
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg aucaauaaca uugcauucag caauugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3157
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3157
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3158
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3158
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga aucaauaaca ucgcuuucag caauugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3159
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3159
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacuaaaa gccaaugcca uaaccacuau ucuaacagca      120

guaacauucu guuucgccuc aggacaaaac auaacagaag aauuuuauca auccaccugu      180

uccgcagucu cgaaaggcua ccuuggcgca cuaagaaccg gaugguauac aucaguaaua      240

accauugaac uaucaaauau caaagaaaua aaaugcaacg gaacugacgc aaaagucaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgccguua cagacuuaca acuacuaaug      360

caaucaacuc cagcaacagg aucaggaucu gcuauaugcu caggugucgc cguauguaaa      420

guguuacacc ucgaaggcga aguaaacaaa auaaaaucag cacuacuauc cacaaauaaa      480

gcaguaguau cacuauccaa ugguguauca guacucacau ucaaaguacu agacuuaaaa      540

aauuauauag auaaacaauu acuaccaaua uuaaacaaac aaucaugcuc aauaccaaac      600

auagaaaccg ucauugaauu ucaacaaaaa aacaaucgac uucuugaaau aacacgagaa      660

uuuucaguaa augccggagu aacaacccca gucucaacau acauguuaac caacucugaa      720

cuccuaagcc uaaucaacga caugcccaua acuaacgacc aaaaaaaacu aauguccaau      780

aauguccaaa uaguaagaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cucgccuaug uaguacaacu acccuuauac ggaguaauug acacaccaug uuggaaacua      900

cauacaucac cacuaugcac cacuaacaca aaagaaggcu ccaacauaug ccuaacccga      960

acagaucgcg gaugguauug cgacaacgca ggaaguguau ccuucuuucc acaagcagaa     1020

acaugcaaag uacaauccaa cagaguauuc ugugacacca ugaacucucu aacacuaccu     1080

uccgaaguaa auuuaugcaa cguagacaua uuuaauccca aauacgacug uaaaauaaug     1140

accucaaaaa cugaugucuc aucaucaguc auuacaucac ucggagcaau agucaguugc     1200

uauggaaaaa ccaaaugcac agcuaguaac aaaaacaggg guauaauaaa aacauuuuca     1260

aacggaugcg auuacguauc aaauaaagga guagacaccg uauccguagg aaauacucuc     1320

uacugcguaa acaaacaaga aggacaaucc cuauacguaa aaggcgaacc aaucauuaac     1380

uuuuacgacc cacuuguauu uccaucagac gaauuugaug ccucaauauc ccaagucaau     1440

gaaaaaauaa accaaagucu agcauucauc cgaaaaucag augaacuuuu acacaacgua     1500

aacgccggaa aaucaacaac aaacaucaug aucacaacaa ucaucauagu aauaauaguu     1560

auacuacuuu ccuuaauagc agucggccua cuacucuacu gcaaagcacg auccacacca     1620

guaaccuuau cuaaagacca acucucaggc auaaacaaca uagcauucuc aaacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3160
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3160
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gcaaacgcca ucacaaccau ccucacagca      120

gucacuuucu gcuucgcauc cggacaaaac aucacagaag aguucuauca auccacgugc      180

uccgcaguuu ccaaaggaua ccuuggagcc uuacgaaccg gcugguacac cuccgucauc      240

accauagaac ucagcaacau caaagaaauc aaaugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aacgcaguca ccgaccucca acuacucaug      360

caaucaaccc ccgcaaccgg cuccggcucc gccaucugcu ccggaguagc cguaugcaaa      420

guccuccacc ucgaaggcga aguuaacaag aucaaguccg cacuccuauc aaccaacaaa      480

gcagucgucu cccuauccaa cggcgucucc guauuaacau ucaaaguccu cgaccucaaa      540

aacuacauag acaaacagcu acuccccauc cuaaacaaac aauccugcuc cauccccaac      600

aucgaaacug ucaucgaguu ccaacagaaa aacaaccgcc uccuagaaau cacccgagag      660

uucuccguaa acgccggcgu cacuaccccc gucucuaccu auaugcuaac caacucugaa      720

cuccuauccc uaaucaacga uaugcccaua acuaacgacc aaaagaaacu uauguccaac      780

aacguacaaa uaguccggca acaaucauac ucuaucaugu gcaucaucaa agaagaagua      840

cuugccuacg uuguccaacu cccacuauac ggcgucauag acacuccaug cuggaaacuu      900

cacaccucac cccucugcac cacuaacacu aaagaaggcu cuaacaucug ccuuacccgc      960

accgaccgcg gaugguacug cgacaacgca ggcucaguua gcuucuuccc acaagccgaa     1020

accugcaaag uccagucaaa ccgugucuuc ugcgauacca ugaacucgcu cacccucccu     1080

uccgaaguca accucugcaa cgucgacauc uucaacccca aauacgacug caaaaucaug     1140

accucaaaaa ccgacguauc uucuuccguc aucaccuccc ucggcgccau cguauccugc     1200

uacggcaaaa ccaaaugcac ugcaucaaac aaaaaccgag gcaucaucaa aaccuucucg     1260

aacggaugcg acuacguauc caacaagggc gucgacacag ucuccguugg uaacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cuauacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccagugac gaauuugacg ccuccaucuc ccaagucaac     1440

gaaaagauca accaaucccu ugccuucaua cgcaaauccg acgaacuccu acacaacguu     1500

aacgccggaa aaucaacaac caacaucaug aucacaacca ucauaaucgu cauaaucguc     1560

auacuccucu cccucauagc cgucggccug cuauuguacu guaaagcccg cuccacacca     1620

gucacacuuu caaaagacca acucuccggg aucaacaaca ucgccuucuc caacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3161
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3161
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1800

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3162
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3162
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      660

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1500

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1560

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1800

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3163
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3163
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1800

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3164
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3164
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      480

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      600

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      660

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      720

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      780

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      840

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      900

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      960

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua     1020

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1080

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg     1140

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1200

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1260

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1320

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1380

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1440

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1500

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1560

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1620

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1680

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1740

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1800

aaagaucaac ucucugggau caauaacauu gcauucagca auugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3165
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3165
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1800

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3166
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3166
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      480

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      600

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      660

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      720

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      780

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      840

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      900

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      960

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug     1020

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc     1080

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc     1140

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1200

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1260

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1320

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1380

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1440

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1500

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1560

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1620

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1680

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1740

cugauugccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1800

aaagaucaac ucuccggaau caauaacauc gcuuucagca auugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3167
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3167
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaauuacuca uacuaaaagc caaugccaua accacuauuc uaacagcagu aacauucugu      300

uucgccucag gacaaaacau aacagaagaa uuuuaucaau ccaccuguuc cgcagucucg      360

aaaggcuacc uuggcgcacu aagaaccgga ugguauacau caguaauaac cauugaacua      420

ucaaauauca aagaaauaaa augcaacgga acugacgcaa aagucaaacu aauaaaacaa      480

gaauuagaca aauacaaaaa cgccguuaca gacuuacaac uacuaaugca aucaacucca      540

gcaacaggau caggaucugc uauaugcuca ggugucgccg uauguaaagu guuacaccuc      600

gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca caaauaaagc aguaguauca      660

cuauccaaug guguaucagu acucacauuc aaaguacuag acuuaaaaaa uuauauagau      720

aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa uaccaaacau agaaaccguc      780

auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa cacgagaauu uucaguaaau      840

gccggaguaa caaccccagu cucaacauac auguuaacca acucugaacu ccuaagccua      900

aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa uguccaauaa uguccaaaua      960

guaagacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu cgccuaugua     1020

guacaacuac ccuuauacgg aguaauugac acaccauguu ggaaacuaca uacaucacca     1080

cuaugcacca cuaacacaaa agaaggcucc aacauaugcc uaacccgaac agaucgcgga     1140

ugguauugcg acaacgcagg aaguguaucc uucuuuccac aagcagaaac augcaaagua     1200

caauccaaca gaguauucug ugacaccaug aacucucuaa cacuaccuuc cgaaguaaau     1260

uuaugcaacg uagacauauu uaaucccaaa uacgacugua aaauaaugac cucaaaaacu     1320

gaugucucau caucagucau uacaucacuc ggagcaauag ucaguugcua uggaaaaacc     1380

aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa cauuuucaaa cggaugcgau     1440

uacguaucaa auaaaggagu agacaccgua uccguaggaa auacucucua cugcguaaac     1500

aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa ucauuaacuu uuacgaccca     1560

cuuguauuuc caucagacga auuugaugcc ucaauauccc aagucaauga aaaaauaaac     1620

caaagucuag cauucauccg aaaaucagau gaacuuuuac acaacguaaa cgccggaaaa     1680

ucaacaacaa acaucaugau cacaacaauc aucauaguaa uaauaguuau acuacuuucc     1740

uuaauagcag ucggccuacu acucuacugc aaagcacgau ccacaccagu aaccuuaucu     1800

aaagaccaac ucucaggcau aaacaacaua gcauucucaa acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3168
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3168
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccuuaaagc aaacgccauc acaaccaucc ucacagcagu cacuuucugc      300

uucgcauccg gacaaaacau cacagaagag uucuaucaau ccacgugcuc cgcaguuucc      360

aaaggauacc uuggagccuu acgaaccggc ugguacaccu ccgucaucac cauagaacuc      420

agcaacauca aagaaaucaa augcaacgga accgacgcaa aagucaaacu caucaaacaa      480

gaacuagaca aauacaaaaa cgcagucacc gaccuccaac uacucaugca aucaaccccc      540

gcaaccggcu ccggcuccgc caucugcucc ggaguagccg uaugcaaagu ccuccaccuc      600

gaaggcgaag uuaacaagau caaguccgca cuccuaucaa ccaacaaagc agucgucucc      660

cuauccaacg gcgucuccgu auuaacauuc aaaguccucg accucaaaaa cuacauagac      720

aaacagcuac uccccauccu aaacaaacaa uccugcucca uccccaacau cgaaacuguc      780

aucgaguucc aacagaaaaa caaccgccuc cuagaaauca cccgagaguu cuccguaaac      840

gccggcguca cuacccccgu cucuaccuau augcuaacca acucugaacu ccuaucccua      900

aucaacgaua ugcccauaac uaacgaccaa aagaaacuua uguccaacaa cguacaaaua      960

guccggcaac aaucauacuc uaucaugugc aucaucaaag aagaaguacu ugccuacguu     1020

guccaacucc cacuauacgg cgucauagac acuccaugcu ggaaacuuca caccucaccc     1080

cucugcacca cuaacacuaa agaaggcucu aacaucugcc uuacccgcac cgaccgcgga     1140

ugguacugcg acaacgcagg cucaguuagc uucuucccac aagccgaaac cugcaaaguc     1200

cagucaaacc gugucuucug cgauaccaug aacucgcuca cccucccuuc cgaagucaac     1260

cucugcaacg ucgacaucuu caaccccaaa uacgacugca aaaucaugac cucaaaaacc     1320

gacguaucuu cuuccgucau caccucccuc ggcgccaucg uauccugcua cggcaaaacc     1380

aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa ccuucucgaa cggaugcgac     1440

uacguaucca acaagggcgu cgacacaguc uccguuggua acacccucua cugcgucaac     1500

aaacaagaag gccaaucccu auacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccagugacga auuugacgcc uccaucuccc aagucaacga aaagaucaac     1620

caaucccuug ccuucauacg caaauccgac gaacuccuac acaacguuaa cgccggaaaa     1680

ucaacaacca acaucaugau cacaaccauc auaaucguca uaaucgucau acuccucucc     1740

cucauagccg ucggccugcu auuguacugu aaagcccgcu ccacaccagu cacacuuuca     1800

aaagaccaac ucuccgggau caacaacauc gccuucucca acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3169
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3169
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3170
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3170
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1620

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3171
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3171
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3172
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3172
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      480

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      540

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      600

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      660

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      720

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      780

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg      960

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1260

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1440

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1500

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1560

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1620

aaagaucaac ucucugggau caauaacauu gcauucagca auugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3173
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3173
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3174
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3174
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      480

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      540

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      600

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      660

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      720

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      780

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc      960

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1140

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1260

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1440

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1500

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1560

cugauugccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1620

aaagaucaac ucuccggaau caauaacauc gcuuucagca auugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3175
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3175
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaauuacuca uacuaaaagc caaugccaua accacuauuc uaacagcagu aacauucugu      120

uucgccucag gacaaaacau aacagaagaa uuuuaucaau ccaccuguuc cgcagucucg      180

aaaggcuacc uuggcgcacu aagaaccgga ugguauacau caguaauaac cauugaacua      240

ucaaauauca aagaaauaaa augcaacgga acugacgcaa aagucaaacu aauaaaacaa      300

gaauuagaca aauacaaaaa cgccguuaca gacuuacaac uacuaaugca aucaacucca      360

gcaacaggau caggaucugc uauaugcuca ggugucgccg uauguaaagu guuacaccuc      420

gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca caaauaaagc aguaguauca      480

cuauccaaug guguaucagu acucacauuc aaaguacuag acuuaaaaaa uuauauagau      540

aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa uaccaaacau agaaaccguc      600

auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa cacgagaauu uucaguaaau      660

gccggaguaa caaccccagu cucaacauac auguuaacca acucugaacu ccuaagccua      720

aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa uguccaauaa uguccaaaua      780

guaagacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu cgccuaugua      840

guacaacuac ccuuauacgg aguaauugac acaccauguu ggaaacuaca uacaucacca      900

cuaugcacca cuaacacaaa agaaggcucc aacauaugcc uaacccgaac agaucgcgga      960

ugguauugcg acaacgcagg aaguguaucc uucuuuccac aagcagaaac augcaaagua     1020

caauccaaca gaguauucug ugacaccaug aacucucuaa cacuaccuuc cgaaguaaau     1080

uuaugcaacg uagacauauu uaaucccaaa uacgacugua aaauaaugac cucaaaaacu     1140

gaugucucau caucagucau uacaucacuc ggagcaauag ucaguugcua uggaaaaacc     1200

aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa cauuuucaaa cggaugcgau     1260

uacguaucaa auaaaggagu agacaccgua uccguaggaa auacucucua cugcguaaac     1320

aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa ucauuaacuu uuacgaccca     1380

cuuguauuuc caucagacga auuugaugcc ucaauauccc aagucaauga aaaaauaaac     1440

caaagucuag cauucauccg aaaaucagau gaacuuuuac acaacguaaa cgccggaaaa     1500

ucaacaacaa acaucaugau cacaacaauc aucauaguaa uaauaguuau acuacuuucc     1560

uuaauagcag ucggccuacu acucuacugc aaagcacgau ccacaccagu aaccuuaucu     1620

aaagaccaac ucucaggcau aaacaacaua gcauucucaa acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3176
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3176
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccuuaaagc aaacgccauc acaaccaucc ucacagcagu cacuuucugc      120

uucgcauccg gacaaaacau cacagaagag uucuaucaau ccacgugcuc cgcaguuucc      180

aaaggauacc uuggagccuu acgaaccggc ugguacaccu ccgucaucac cauagaacuc      240

agcaacauca aagaaaucaa augcaacgga accgacgcaa aagucaaacu caucaaacaa      300

gaacuagaca aauacaaaaa cgcagucacc gaccuccaac uacucaugca aucaaccccc      360

gcaaccggcu ccggcuccgc caucugcucc ggaguagccg uaugcaaagu ccuccaccuc      420

gaaggcgaag uuaacaagau caaguccgca cuccuaucaa ccaacaaagc agucgucucc      480

cuauccaacg gcgucuccgu auuaacauuc aaaguccucg accucaaaaa cuacauagac      540

aaacagcuac uccccauccu aaacaaacaa uccugcucca uccccaacau cgaaacuguc      600

aucgaguucc aacagaaaaa caaccgccuc cuagaaauca cccgagaguu cuccguaaac      660

gccggcguca cuacccccgu cucuaccuau augcuaacca acucugaacu ccuaucccua      720

aucaacgaua ugcccauaac uaacgaccaa aagaaacuua uguccaacaa cguacaaaua      780

guccggcaac aaucauacuc uaucaugugc aucaucaaag aagaaguacu ugccuacguu      840

guccaacucc cacuauacgg cgucauagac acuccaugcu ggaaacuuca caccucaccc      900

cucugcacca cuaacacuaa agaaggcucu aacaucugcc uuacccgcac cgaccgcgga      960

ugguacugcg acaacgcagg cucaguuagc uucuucccac aagccgaaac cugcaaaguc     1020

cagucaaacc gugucuucug cgauaccaug aacucgcuca cccucccuuc cgaagucaac     1080

cucugcaacg ucgacaucuu caaccccaaa uacgacugca aaaucaugac cucaaaaacc     1140

gacguaucuu cuuccgucau caccucccuc ggcgccaucg uauccugcua cggcaaaacc     1200

aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa ccuucucgaa cggaugcgac     1260

uacguaucca acaagggcgu cgacacaguc uccguuggua acacccucua cugcgucaac     1320

aaacaagaag gccaaucccu auacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccagugacga auuugacgcc uccaucuccc aagucaacga aaagaucaac     1440

caaucccuug ccuucauacg caaauccgac gaacuccuac acaacguuaa cgccggaaaa     1500

ucaacaacca acaucaugau cacaaccauc auaaucguca uaaucgucau acuccucucc     1560

cucauagccg ucggccugcu auuguacugu aaagcccgcu ccacaccagu cacacuuuca     1620

aaagaccaac ucuccgggau caacaacauc gccuucucca acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3177
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3177
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3178
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3178
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3179
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3179
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3180
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3180
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau caauaacauu gcauucagca     1680

auugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3181
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3181
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3182
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3182
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau caauaacauc gcuuucagca     1680

auugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3183
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3183
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacuaaaagc caaugccaua accacuauuc      120

uaacagcagu aacauucugu uucgccucag gacaaaacau aacagaagaa uuuuaucaau      180

ccaccuguuc cgcagucucg aaaggcuacc uuggcgcacu aagaaccgga ugguauacau      240

caguaauaac cauugaacua ucaaauauca aagaaauaaa augcaacgga acugacgcaa      300

aagucaaacu aauaaaacaa gaauuagaca aauacaaaaa cgccguuaca gacuuacaac      360

uacuaaugca aucaacucca gcaacaggau caggaucugc uauaugcuca ggugucgccg      420

uauguaaagu guuacaccuc gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca      480

caaauaaagc aguaguauca cuauccaaug guguaucagu acucacauuc aaaguacuag      540

acuuaaaaaa uuauauagau aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa      600

uaccaaacau agaaaccguc auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa      660

cacgagaauu uucaguaaau gccggaguaa caaccccagu cucaacauac auguuaacca      720

acucugaacu ccuaagccua aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa      780

uguccaauaa uguccaaaua guaagacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu cgccuaugua guacaacuac ccuuauacgg aguaauugac acaccauguu      900

ggaaacuaca uacaucacca cuaugcacca cuaacacaaa agaaggcucc aacauaugcc      960

uaacccgaac agaucgcgga ugguauugcg acaacgcagg aaguguaucc uucuuuccac     1020

aagcagaaac augcaaagua caauccaaca gaguauucug ugacaccaug aacucucuaa     1080

cacuaccuuc cgaaguaaau uuaugcaacg uagacauauu uaaucccaaa uacgacugua     1140

aaauaaugac cucaaaaacu gaugucucau caucagucau uacaucacuc ggagcaauag     1200

ucaguugcua uggaaaaacc aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa     1260

cauuuucaaa cggaugcgau uacguaucaa auaaaggagu agacaccgua uccguaggaa     1320

auacucucua cugcguaaac aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa     1380

ucauuaacuu uuacgaccca cuuguauuuc caucagacga auuugaugcc ucaauauccc     1440

aagucaauga aaaaauaaac caaagucuag cauucauccg aaaaucagau gaacuuuuac     1500

acaacguaaa cgccggaaaa ucaacaacaa acaucaugau cacaacaauc aucauaguaa     1560

uaauaguuau acuacuuucc uuaauagcag ucggccuacu acucuacugc aaagcacgau     1620

ccacaccagu aaccuuaucu aaagaccaac ucucaggcau aaacaacaua gcauucucaa     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3184
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3184
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc aaacgccauc acaaccaucc      120

ucacagcagu cacuuucugc uucgcauccg gacaaaacau cacagaagag uucuaucaau      180

ccacgugcuc cgcaguuucc aaaggauacc uuggagccuu acgaaccggc ugguacaccu      240

ccgucaucac cauagaacuc agcaacauca aagaaaucaa augcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa cgcagucacc gaccuccaac      360

uacucaugca aucaaccccc gcaaccggcu ccggcuccgc caucugcucc ggaguagccg      420

uaugcaaagu ccuccaccuc gaaggcgaag uuaacaagau caaguccgca cuccuaucaa      480

ccaacaaagc agucgucucc cuauccaacg gcgucuccgu auuaacauuc aaaguccucg      540

accucaaaaa cuacauagac aaacagcuac uccccauccu aaacaaacaa uccugcucca      600

uccccaacau cgaaacuguc aucgaguucc aacagaaaaa caaccgccuc cuagaaauca      660

cccgagaguu cuccguaaac gccggcguca cuacccccgu cucuaccuau augcuaacca      720

acucugaacu ccuaucccua aucaacgaua ugcccauaac uaacgaccaa aagaaacuua      780

uguccaacaa cguacaaaua guccggcaac aaucauacuc uaucaugugc aucaucaaag      840

aagaaguacu ugccuacguu guccaacucc cacuauacgg cgucauagac acuccaugcu      900

ggaaacuuca caccucaccc cucugcacca cuaacacuaa agaaggcucu aacaucugcc      960

uuacccgcac cgaccgcgga ugguacugcg acaacgcagg cucaguuagc uucuucccac     1020

aagccgaaac cugcaaaguc cagucaaacc gugucuucug cgauaccaug aacucgcuca     1080

cccucccuuc cgaagucaac cucugcaacg ucgacaucuu caaccccaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacguaucuu cuuccgucau caccucccuc ggcgccaucg     1200

uauccugcua cggcaaaacc aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa     1260

ccuucucgaa cggaugcgac uacguaucca acaagggcgu cgacacaguc uccguuggua     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu auacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccagugacga auuugacgcc uccaucuccc     1440

aagucaacga aaagaucaac caaucccuug ccuucauacg caaauccgac gaacuccuac     1500

acaacguuaa cgccggaaaa ucaacaacca acaucaugau cacaaccauc auaaucguca     1560

uaaucgucau acuccucucc cucauagccg ucggccugcu auuguacugu aaagcccgcu     1620

ccacaccagu cacacuuuca aaagaccaac ucuccgggau caacaacauc gccuucucca     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3185
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3185
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3186
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3186
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3187
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3187
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3188
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3188
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau caauaacauu gcauucagca     1680

auugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3189
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3189
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3190
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3190
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau caauaacauc gcuuucagca     1680

auugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3191
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3191
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacuaaaagc caaugccaua accacuauuc      120

uaacagcagu aacauucugu uucgccucag gacaaaacau aacagaagaa uuuuaucaau      180

ccaccuguuc cgcagucucg aaaggcuacc uuggcgcacu aagaaccgga ugguauacau      240

caguaauaac cauugaacua ucaaauauca aagaaauaaa augcaacgga acugacgcaa      300

aagucaaacu aauaaaacaa gaauuagaca aauacaaaaa cgccguuaca gacuuacaac      360

uacuaaugca aucaacucca gcaacaggau caggaucugc uauaugcuca ggugucgccg      420

uauguaaagu guuacaccuc gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca      480

caaauaaagc aguaguauca cuauccaaug guguaucagu acucacauuc aaaguacuag      540

acuuaaaaaa uuauauagau aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa      600

uaccaaacau agaaaccguc auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa      660

cacgagaauu uucaguaaau gccggaguaa caaccccagu cucaacauac auguuaacca      720

acucugaacu ccuaagccua aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa      780

uguccaauaa uguccaaaua guaagacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu cgccuaugua guacaacuac ccuuauacgg aguaauugac acaccauguu      900

ggaaacuaca uacaucacca cuaugcacca cuaacacaaa agaaggcucc aacauaugcc      960

uaacccgaac agaucgcgga ugguauugcg acaacgcagg aaguguaucc uucuuuccac     1020

aagcagaaac augcaaagua caauccaaca gaguauucug ugacaccaug aacucucuaa     1080

cacuaccuuc cgaaguaaau uuaugcaacg uagacauauu uaaucccaaa uacgacugua     1140

aaauaaugac cucaaaaacu gaugucucau caucagucau uacaucacuc ggagcaauag     1200

ucaguugcua uggaaaaacc aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa     1260

cauuuucaaa cggaugcgau uacguaucaa auaaaggagu agacaccgua uccguaggaa     1320

auacucucua cugcguaaac aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa     1380

ucauuaacuu uuacgaccca cuuguauuuc caucagacga auuugaugcc ucaauauccc     1440

aagucaauga aaaaauaaac caaagucuag cauucauccg aaaaucagau gaacuuuuac     1500

acaacguaaa cgccggaaaa ucaacaacaa acaucaugau cacaacaauc aucauaguaa     1560

uaauaguuau acuacuuucc uuaauagcag ucggccuacu acucuacugc aaagcacgau     1620

ccacaccagu aaccuuaucu aaagaccaac ucucaggcau aaacaacaua gcauucucaa     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3192
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3192
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc aaacgccauc acaaccaucc      120

ucacagcagu cacuuucugc uucgcauccg gacaaaacau cacagaagag uucuaucaau      180

ccacgugcuc cgcaguuucc aaaggauacc uuggagccuu acgaaccggc ugguacaccu      240

ccgucaucac cauagaacuc agcaacauca aagaaaucaa augcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa cgcagucacc gaccuccaac      360

uacucaugca aucaaccccc gcaaccggcu ccggcuccgc caucugcucc ggaguagccg      420

uaugcaaagu ccuccaccuc gaaggcgaag uuaacaagau caaguccgca cuccuaucaa      480

ccaacaaagc agucgucucc cuauccaacg gcgucuccgu auuaacauuc aaaguccucg      540

accucaaaaa cuacauagac aaacagcuac uccccauccu aaacaaacaa uccugcucca      600

uccccaacau cgaaacuguc aucgaguucc aacagaaaaa caaccgccuc cuagaaauca      660

cccgagaguu cuccguaaac gccggcguca cuacccccgu cucuaccuau augcuaacca      720

acucugaacu ccuaucccua aucaacgaua ugcccauaac uaacgaccaa aagaaacuua      780

uguccaacaa cguacaaaua guccggcaac aaucauacuc uaucaugugc aucaucaaag      840

aagaaguacu ugccuacguu guccaacucc cacuauacgg cgucauagac acuccaugcu      900

ggaaacuuca caccucaccc cucugcacca cuaacacuaa agaaggcucu aacaucugcc      960

uuacccgcac cgaccgcgga ugguacugcg acaacgcagg cucaguuagc uucuucccac     1020

aagccgaaac cugcaaaguc cagucaaacc gugucuucug cgauaccaug aacucgcuca     1080

cccucccuuc cgaagucaac cucugcaacg ucgacaucuu caaccccaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacguaucuu cuuccgucau caccucccuc ggcgccaucg     1200

uauccugcua cggcaaaacc aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa     1260

ccuucucgaa cggaugcgac uacguaucca acaagggcgu cgacacaguc uccguuggua     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu auacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccagugacga auuugacgcc uccaucuccc     1440

aagucaacga aaagaucaac caaucccuug ccuucauacg caaauccgac gaacuccuac     1500

acaacguuaa cgccggaaaa ucaacaacca acaucaugau cacaaccauc auaaucguca     1560

uaaucgucau acuccucucc cucauagccg ucggccugcu auuguacugu aaagcccgcu     1620

ccacaccagu cacacuuuca aaagaccaac ucuccgggau caacaacauc gccuucucca     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3193
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3193
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3194
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3194
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3195
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3195
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3196
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3196
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggaucaau aacauugcau ucagcaauug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3197
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3197
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3198
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3198
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaaucaau aacaucgcuu ucagcaauug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3199
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3199
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu aaaagccaau gccauaacca cuauucuaac agcaguaaca      180

uucuguuucg ccucaggaca aaacauaaca gaagaauuuu aucaauccac cuguuccgca      240

gucucgaaag gcuaccuugg cgcacuaaga accggauggu auacaucagu aauaaccauu      300

gaacuaucaa auaucaaaga aauaaaaugc aacggaacug acgcaaaagu caaacuaaua      360

aaacaagaau uagacaaaua caaaaacgcc guuacagacu uacaacuacu aaugcaauca      420

acuccagcaa caggaucagg aucugcuaua ugcucaggug ucgccguaug uaaaguguua      480

caccucgaag gcgaaguaaa caaaauaaaa ucagcacuac uauccacaaa uaaagcagua      540

guaucacuau ccaauggugu aucaguacuc acauucaaag uacuagacuu aaaaaauuau      600

auagauaaac aauuacuacc aauauuaaac aaacaaucau gcucaauacc aaacauagaa      660

accgucauug aauuucaaca aaaaaacaau cgacuucuug aaauaacacg agaauuuuca      720

guaaaugccg gaguaacaac cccagucuca acauacaugu uaaccaacuc ugaacuccua      780

agccuaauca acgacaugcc cauaacuaac gaccaaaaaa aacuaauguc caauaauguc      840

caaauaguaa gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccucgcc      900

uauguaguac aacuacccuu auacggagua auugacacac cauguuggaa acuacauaca      960

ucaccacuau gcaccacuaa cacaaaagaa ggcuccaaca uaugccuaac ccgaacagau     1020

cgcggauggu auugcgacaa cgcaggaagu guauccuucu uuccacaagc agaaacaugc     1080

aaaguacaau ccaacagagu auucugugac accaugaacu cucuaacacu accuuccgaa     1140

guaaauuuau gcaacguaga cauauuuaau cccaaauacg acuguaaaau aaugaccuca     1200

aaaacugaug ucucaucauc agucauuaca ucacucggag caauagucag uugcuaugga     1260

aaaaccaaau gcacagcuag uaacaaaaac agggguauaa uaaaaacauu uucaaacgga     1320

ugcgauuacg uaucaaauaa aggaguagac accguauccg uaggaaauac ucucuacugc     1380

guaaacaaac aagaaggaca aucccuauac guaaaaggcg aaccaaucau uaacuuuuac     1440

gacccacuug uauuuccauc agacgaauuu gaugccucaa uaucccaagu caaugaaaaa     1500

auaaaccaaa gucuagcauu cauccgaaaa ucagaugaac uuuuacacaa cguaaacgcc     1560

ggaaaaucaa caacaaacau caugaucaca acaaucauca uaguaauaau aguuauacua     1620

cuuuccuuaa uagcagucgg ccuacuacuc uacugcaaag cacgauccac accaguaacc     1680

uuaucuaaag accaacucuc aggcauaaac aacauagcau ucucaaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3200
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3200
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagcaaac gccaucacaa ccauccucac agcagucacu      180

uucugcuucg cauccggaca aaacaucaca gaagaguucu aucaauccac gugcuccgca      240

guuuccaaag gauaccuugg agccuuacga accggcuggu acaccuccgu caucaccaua      300

gaacucagca acaucaaaga aaucaaaugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaacgca gucaccgacc uccaacuacu caugcaauca      420

acccccgcaa ccggcuccgg cuccgccauc ugcuccggag uagccguaug caaaguccuc      480

caccucgaag gcgaaguuaa caagaucaag uccgcacucc uaucaaccaa caaagcaguc      540

gucucccuau ccaacggcgu cuccguauua acauucaaag uccucgaccu caaaaacuac      600

auagacaaac agcuacuccc cauccuaaac aaacaauccu gcuccauccc caacaucgaa      660

acugucaucg aguuccaaca gaaaaacaac cgccuccuag aaaucacccg agaguucucc      720

guaaacgccg gcgucacuac ccccgucucu accuauaugc uaaccaacuc ugaacuccua      780

ucccuaauca acgauaugcc cauaacuaac gaccaaaaga aacuuauguc caacaacgua      840

caaauagucc ggcaacaauc auacucuauc augugcauca ucaaagaaga aguacuugcc      900

uacguugucc aacucccacu auacggcguc auagacacuc caugcuggaa acuucacacc      960

ucaccccucu gcaccacuaa cacuaaagaa ggcucuaaca ucugccuuac ccgcaccgac     1020

cgcggauggu acugcgacaa cgcaggcuca guuagcuucu ucccacaagc cgaaaccugc     1080

aaaguccagu caaaccgugu cuucugcgau accaugaacu cgcucacccu cccuuccgaa     1140

gucaaccucu gcaacgucga caucuucaac cccaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg uaucuucuuc cgucaucacc ucccucggcg ccaucguauc cugcuacggc     1260

aaaaccaaau gcacugcauc aaacaaaaac cgaggcauca ucaaaaccuu cucgaacgga     1320

ugcgacuacg uauccaacaa gggcgucgac acagucuccg uugguaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccuauac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccag ugacgaauuu gacgccucca ucucccaagu caacgaaaag     1500

aucaaccaau cccuugccuu cauacgcaaa uccgacgaac uccuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaacau caugaucaca accaucauaa ucgucauaau cgucauacuc     1620

cucucccuca uagccgucgg ccugcuauug uacuguaaag cccgcuccac accagucaca     1680

cuuucaaaag accaacucuc cgggaucaac aacaucgccu ucuccaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3201
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3201
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3202
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3202
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3203
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3203
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3204
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3204
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggauc     1680

aauaacauug cauucagcaa uugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3205
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3205
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3206
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3206
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauc     1680

aauaacaucg cuuucagcaa uugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3207
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3207
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acuaaaagcc      120

aaugccauaa ccacuauucu aacagcagua acauucuguu ucgccucagg acaaaacaua      180

acagaagaau uuuaucaauc caccuguucc gcagucucga aaggcuaccu uggcgcacua      240

agaaccggau gguauacauc aguaauaacc auugaacuau caaauaucaa agaaauaaaa      300

ugcaacggaa cugacgcaaa agucaaacua auaaaacaag aauuagacaa auacaaaaac      360

gccguuacag acuuacaacu acuaaugcaa ucaacuccag caacaggauc aggaucugcu      420

auaugcucag gugucgccgu auguaaagug uuacaccucg aaggcgaagu aaacaaaaua      480

aaaucagcac uacuauccac aaauaaagca guaguaucac uauccaaugg uguaucagua      540

cucacauuca aaguacuaga cuuaaaaaau uauauagaua aacaauuacu accaauauua      600

aacaaacaau caugcucaau accaaacaua gaaaccguca uugaauuuca acaaaaaaac      660

aaucgacuuc uugaaauaac acgagaauuu ucaguaaaug ccggaguaac aaccccaguc      720

ucaacauaca uguuaaccaa cucugaacuc cuaagccuaa ucaacgacau gcccauaacu      780

aacgaccaaa aaaaacuaau guccaauaau guccaaauag uaagacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccuc gccuauguag uacaacuacc cuuauacgga      900

guaauugaca caccauguug gaaacuacau acaucaccac uaugcaccac uaacacaaaa      960

gaaggcucca acauaugccu aacccgaaca gaucgcggau gguauugcga caacgcagga     1020

aguguauccu ucuuuccaca agcagaaaca ugcaaaguac aauccaacag aguauucugu     1080

gacaccauga acucucuaac acuaccuucc gaaguaaauu uaugcaacgu agacauauuu     1140

aaucccaaau acgacuguaa aauaaugacc ucaaaaacug augucucauc aucagucauu     1200

acaucacucg gagcaauagu caguugcuau ggaaaaacca aaugcacagc uaguaacaaa     1260

aacaggggua uaauaaaaac auuuucaaac ggaugcgauu acguaucaaa uaaaggagua     1320

gacaccguau ccguaggaaa uacucucuac ugcguaaaca aacaagaagg acaaucccua     1380

uacguaaaag gcgaaccaau cauuaacuuu uacgacccac uuguauuucc aucagacgaa     1440

uuugaugccu caauauccca agucaaugaa aaaauaaacc aaagucuagc auucauccga     1500

aaaucagaug aacuuuuaca caacguaaac gccggaaaau caacaacaaa caucaugauc     1560

acaacaauca ucauaguaau aauaguuaua cuacuuuccu uaauagcagu cggccuacua     1620

cucuacugca aagcacgauc cacaccagua accuuaucua aagaccaacu cucaggcaua     1680

aacaacauag cauucucaaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3208
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3208
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagca      120

aacgccauca caaccauccu cacagcaguc acuuucugcu ucgcauccgg acaaaacauc      180

acagaagagu ucuaucaauc cacgugcucc gcaguuucca aaggauaccu uggagccuua      240

cgaaccggcu gguacaccuc cgucaucacc auagaacuca gcaacaucaa agaaaucaaa      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaaaaac      360

gcagucaccg accuccaacu acucaugcaa ucaacccccg caaccggcuc cggcuccgcc      420

aucugcuccg gaguagccgu augcaaaguc cuccaccucg aaggcgaagu uaacaagauc      480

aaguccgcac uccuaucaac caacaaagca gucgucuccc uauccaacgg cgucuccgua      540

uuaacauuca aaguccucga ccucaaaaac uacauagaca aacagcuacu ccccauccua      600

aacaaacaau ccugcuccau ccccaacauc gaaacuguca ucgaguucca acagaaaaac      660

aaccgccucc uagaaaucac ccgagaguuc uccguaaacg ccggcgucac uacccccguc      720

ucuaccuaua ugcuaaccaa cucugaacuc cuaucccuaa ucaacgauau gcccauaacu      780

aacgaccaaa agaaacuuau guccaacaac guacaaauag uccggcaaca aucauacucu      840

aucaugugca ucaucaaaga agaaguacuu gccuacguug uccaacuccc acuauacggc      900

gucauagaca cuccaugcug gaaacuucac accucacccc ucugcaccac uaacacuaaa      960

gaaggcucua acaucugccu uacccgcacc gaccgcggau gguacugcga caacgcaggc     1020

ucaguuagcu ucuucccaca agccgaaacc ugcaaagucc agucaaaccg ugucuucugc     1080

gauaccauga acucgcucac ccucccuucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucaaaaaccg acguaucuuc uuccgucauc     1200

accucccucg gcgccaucgu auccugcuac ggcaaaacca aaugcacugc aucaaacaaa     1260

aaccgaggca ucaucaaaac cuucucgaac ggaugcgacu acguauccaa caagggcguc     1320

gacacagucu ccguugguaa cacccucuac ugcgucaaca aacaagaagg ccaaucccua     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cagugacgaa     1440

uuugacgccu ccaucuccca agucaacgaa aagaucaacc aaucccuugc cuucauacgc     1500

aaauccgacg aacuccuaca caacguuaac gccggaaaau caacaaccaa caucaugauc     1560

acaaccauca uaaucgucau aaucgucaua cuccucuccc ucauagccgu cggccugcua     1620

uuguacugua aagcccgcuc cacaccaguc acacuuucaa aagaccaacu cuccgggauc     1680

aacaacaucg ccuucuccaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3209
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3209
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3210
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3210
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3211
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3211
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3212
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3212
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggaucaau aacauugcau ucagcaauug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3213
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3213
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3214
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3214
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaaucaau aacaucgcuu ucagcaauug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3215
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3215
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu aaaagccaau gccauaacca cuauucuaac agcaguaaca      180

uucuguuucg ccucaggaca aaacauaaca gaagaauuuu aucaauccac cuguuccgca      240

gucucgaaag gcuaccuugg cgcacuaaga accggauggu auacaucagu aauaaccauu      300

gaacuaucaa auaucaaaga aauaaaaugc aacggaacug acgcaaaagu caaacuaaua      360

aaacaagaau uagacaaaua caaaaacgcc guuacagacu uacaacuacu aaugcaauca      420

acuccagcaa caggaucagg aucugcuaua ugcucaggug ucgccguaug uaaaguguua      480

caccucgaag gcgaaguaaa caaaauaaaa ucagcacuac uauccacaaa uaaagcagua      540

guaucacuau ccaauggugu aucaguacuc acauucaaag uacuagacuu aaaaaauuau      600

auagauaaac aauuacuacc aauauuaaac aaacaaucau gcucaauacc aaacauagaa      660

accgucauug aauuucaaca aaaaaacaau cgacuucuug aaauaacacg agaauuuuca      720

guaaaugccg gaguaacaac cccagucuca acauacaugu uaaccaacuc ugaacuccua      780

agccuaauca acgacaugcc cauaacuaac gaccaaaaaa aacuaauguc caauaauguc      840

caaauaguaa gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccucgcc      900

uauguaguac aacuacccuu auacggagua auugacacac cauguuggaa acuacauaca      960

ucaccacuau gcaccacuaa cacaaaagaa ggcuccaaca uaugccuaac ccgaacagau     1020

cgcggauggu auugcgacaa cgcaggaagu guauccuucu uuccacaagc agaaacaugc     1080

aaaguacaau ccaacagagu auucugugac accaugaacu cucuaacacu accuuccgaa     1140

guaaauuuau gcaacguaga cauauuuaau cccaaauacg acuguaaaau aaugaccuca     1200

aaaacugaug ucucaucauc agucauuaca ucacucggag caauagucag uugcuaugga     1260

aaaaccaaau gcacagcuag uaacaaaaac agggguauaa uaaaaacauu uucaaacgga     1320

ugcgauuacg uaucaaauaa aggaguagac accguauccg uaggaaauac ucucuacugc     1380

guaaacaaac aagaaggaca aucccuauac guaaaaggcg aaccaaucau uaacuuuuac     1440

gacccacuug uauuuccauc agacgaauuu gaugccucaa uaucccaagu caaugaaaaa     1500

auaaaccaaa gucuagcauu cauccgaaaa ucagaugaac uuuuacacaa cguaaacgcc     1560

ggaaaaucaa caacaaacau caugaucaca acaaucauca uaguaauaau aguuauacua     1620

cuuuccuuaa uagcagucgg ccuacuacuc uacugcaaag cacgauccac accaguaacc     1680

uuaucuaaag accaacucuc aggcauaaac aacauagcau ucucaaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3216
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3216
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagcaaac gccaucacaa ccauccucac agcagucacu      180

uucugcuucg cauccggaca aaacaucaca gaagaguucu aucaauccac gugcuccgca      240

guuuccaaag gauaccuugg agccuuacga accggcuggu acaccuccgu caucaccaua      300

gaacucagca acaucaaaga aaucaaaugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaacgca gucaccgacc uccaacuacu caugcaauca      420

acccccgcaa ccggcuccgg cuccgccauc ugcuccggag uagccguaug caaaguccuc      480

caccucgaag gcgaaguuaa caagaucaag uccgcacucc uaucaaccaa caaagcaguc      540

gucucccuau ccaacggcgu cuccguauua acauucaaag uccucgaccu caaaaacuac      600

auagacaaac agcuacuccc cauccuaaac aaacaauccu gcuccauccc caacaucgaa      660

acugucaucg aguuccaaca gaaaaacaac cgccuccuag aaaucacccg agaguucucc      720

guaaacgccg gcgucacuac ccccgucucu accuauaugc uaaccaacuc ugaacuccua      780

ucccuaauca acgauaugcc cauaacuaac gaccaaaaga aacuuauguc caacaacgua      840

caaauagucc ggcaacaauc auacucuauc augugcauca ucaaagaaga aguacuugcc      900

uacguugucc aacucccacu auacggcguc auagacacuc caugcuggaa acuucacacc      960

ucaccccucu gcaccacuaa cacuaaagaa ggcucuaaca ucugccuuac ccgcaccgac     1020

cgcggauggu acugcgacaa cgcaggcuca guuagcuucu ucccacaagc cgaaaccugc     1080

aaaguccagu caaaccgugu cuucugcgau accaugaacu cgcucacccu cccuuccgaa     1140

gucaaccucu gcaacgucga caucuucaac cccaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg uaucuucuuc cgucaucacc ucccucggcg ccaucguauc cugcuacggc     1260

aaaaccaaau gcacugcauc aaacaaaaac cgaggcauca ucaaaaccuu cucgaacgga     1320

ugcgacuacg uauccaacaa gggcgucgac acagucuccg uugguaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccuauac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccag ugacgaauuu gacgccucca ucucccaagu caacgaaaag     1500

aucaaccaau cccuugccuu cauacgcaaa uccgacgaac uccuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaacau caugaucaca accaucauaa ucgucauaau cgucauacuc     1620

cucucccuca uagccgucgg ccugcuauug uacuguaaag cccgcuccac accagucaca     1680

cuuucaaaag accaacucuc cgggaucaac aacaucgccu ucuccaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3217
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3217
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3218
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3218
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3219
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3219
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3220
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3220
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggauc     1680

aauaacauug cauucagcaa uugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3221
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3221
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3222
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3222
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauc     1680

aauaacaucg cuuucagcaa uugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3223
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3223
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acuaaaagcc      120

aaugccauaa ccacuauucu aacagcagua acauucuguu ucgccucagg acaaaacaua      180

acagaagaau uuuaucaauc caccuguucc gcagucucga aaggcuaccu uggcgcacua      240

agaaccggau gguauacauc aguaauaacc auugaacuau caaauaucaa agaaauaaaa      300

ugcaacggaa cugacgcaaa agucaaacua auaaaacaag aauuagacaa auacaaaaac      360

gccguuacag acuuacaacu acuaaugcaa ucaacuccag caacaggauc aggaucugcu      420

auaugcucag gugucgccgu auguaaagug uuacaccucg aaggcgaagu aaacaaaaua      480

aaaucagcac uacuauccac aaauaaagca guaguaucac uauccaaugg uguaucagua      540

cucacauuca aaguacuaga cuuaaaaaau uauauagaua aacaauuacu accaauauua      600

aacaaacaau caugcucaau accaaacaua gaaaccguca uugaauuuca acaaaaaaac      660

aaucgacuuc uugaaauaac acgagaauuu ucaguaaaug ccggaguaac aaccccaguc      720

ucaacauaca uguuaaccaa cucugaacuc cuaagccuaa ucaacgacau gcccauaacu      780

aacgaccaaa aaaaacuaau guccaauaau guccaaauag uaagacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccuc gccuauguag uacaacuacc cuuauacgga      900

guaauugaca caccauguug gaaacuacau acaucaccac uaugcaccac uaacacaaaa      960

gaaggcucca acauaugccu aacccgaaca gaucgcggau gguauugcga caacgcagga     1020

aguguauccu ucuuuccaca agcagaaaca ugcaaaguac aauccaacag aguauucugu     1080

gacaccauga acucucuaac acuaccuucc gaaguaaauu uaugcaacgu agacauauuu     1140

aaucccaaau acgacuguaa aauaaugacc ucaaaaacug augucucauc aucagucauu     1200

acaucacucg gagcaauagu caguugcuau ggaaaaacca aaugcacagc uaguaacaaa     1260

aacaggggua uaauaaaaac auuuucaaac ggaugcgauu acguaucaaa uaaaggagua     1320

gacaccguau ccguaggaaa uacucucuac ugcguaaaca aacaagaagg acaaucccua     1380

uacguaaaag gcgaaccaau cauuaacuuu uacgacccac uuguauuucc aucagacgaa     1440

uuugaugccu caauauccca agucaaugaa aaaauaaacc aaagucuagc auucauccga     1500

aaaucagaug aacuuuuaca caacguaaac gccggaaaau caacaacaaa caucaugauc     1560

acaacaauca ucauaguaau aauaguuaua cuacuuuccu uaauagcagu cggccuacua     1620

cucuacugca aagcacgauc cacaccagua accuuaucua aagaccaacu cucaggcaua     1680

aacaacauag cauucucaaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3224
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3224
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagca      120

aacgccauca caaccauccu cacagcaguc acuuucugcu ucgcauccgg acaaaacauc      180

acagaagagu ucuaucaauc cacgugcucc gcaguuucca aaggauaccu uggagccuua      240

cgaaccggcu gguacaccuc cgucaucacc auagaacuca gcaacaucaa agaaaucaaa      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaaaaac      360

gcagucaccg accuccaacu acucaugcaa ucaacccccg caaccggcuc cggcuccgcc      420

aucugcuccg gaguagccgu augcaaaguc cuccaccucg aaggcgaagu uaacaagauc      480

aaguccgcac uccuaucaac caacaaagca gucgucuccc uauccaacgg cgucuccgua      540

uuaacauuca aaguccucga ccucaaaaac uacauagaca aacagcuacu ccccauccua      600

aacaaacaau ccugcuccau ccccaacauc gaaacuguca ucgaguucca acagaaaaac      660

aaccgccucc uagaaaucac ccgagaguuc uccguaaacg ccggcgucac uacccccguc      720

ucuaccuaua ugcuaaccaa cucugaacuc cuaucccuaa ucaacgauau gcccauaacu      780

aacgaccaaa agaaacuuau guccaacaac guacaaauag uccggcaaca aucauacucu      840

aucaugugca ucaucaaaga agaaguacuu gccuacguug uccaacuccc acuauacggc      900

gucauagaca cuccaugcug gaaacuucac accucacccc ucugcaccac uaacacuaaa      960

gaaggcucua acaucugccu uacccgcacc gaccgcggau gguacugcga caacgcaggc     1020

ucaguuagcu ucuucccaca agccgaaacc ugcaaagucc agucaaaccg ugucuucugc     1080

gauaccauga acucgcucac ccucccuucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucaaaaaccg acguaucuuc uuccgucauc     1200

accucccucg gcgccaucgu auccugcuac ggcaaaacca aaugcacugc aucaaacaaa     1260

aaccgaggca ucaucaaaac cuucucgaac ggaugcgacu acguauccaa caagggcguc     1320

gacacagucu ccguugguaa cacccucuac ugcgucaaca aacaagaagg ccaaucccua     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cagugacgaa     1440

uuugacgccu ccaucuccca agucaacgaa aagaucaacc aaucccuugc cuucauacgc     1500

aaauccgacg aacuccuaca caacguuaac gccggaaaau caacaaccaa caucaugauc     1560

acaaccauca uaaucgucau aaucgucaua cuccucuccc ucauagccgu cggccugcua     1620

uuguacugua aagcccgcuc cacaccaguc acacuuucaa aagaccaacu cuccgggauc     1680

aacaacaucg ccuucuccaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3225
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3225
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3226
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3226
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3227
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3227
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3228
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3228
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggauc     1680

aauaacauug cauucagcaa uugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3229
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3229
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3230
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3230
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauc     1680

aauaacaucg cuuucagcaa uugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3231
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3231
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acuaaaagcc      120

aaugccauaa ccacuauucu aacagcagua acauucuguu ucgccucagg acaaaacaua      180

acagaagaau uuuaucaauc caccuguucc gcagucucga aaggcuaccu uggcgcacua      240

agaaccggau gguauacauc aguaauaacc auugaacuau caaauaucaa agaaauaaaa      300

ugcaacggaa cugacgcaaa agucaaacua auaaaacaag aauuagacaa auacaaaaac      360

gccguuacag acuuacaacu acuaaugcaa ucaacuccag caacaggauc aggaucugcu      420

auaugcucag gugucgccgu auguaaagug uuacaccucg aaggcgaagu aaacaaaaua      480

aaaucagcac uacuauccac aaauaaagca guaguaucac uauccaaugg uguaucagua      540

cucacauuca aaguacuaga cuuaaaaaau uauauagaua aacaauuacu accaauauua      600

aacaaacaau caugcucaau accaaacaua gaaaccguca uugaauuuca acaaaaaaac      660

aaucgacuuc uugaaauaac acgagaauuu ucaguaaaug ccggaguaac aaccccaguc      720

ucaacauaca uguuaaccaa cucugaacuc cuaagccuaa ucaacgacau gcccauaacu      780

aacgaccaaa aaaaacuaau guccaauaau guccaaauag uaagacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccuc gccuauguag uacaacuacc cuuauacgga      900

guaauugaca caccauguug gaaacuacau acaucaccac uaugcaccac uaacacaaaa      960

gaaggcucca acauaugccu aacccgaaca gaucgcggau gguauugcga caacgcagga     1020

aguguauccu ucuuuccaca agcagaaaca ugcaaaguac aauccaacag aguauucugu     1080

gacaccauga acucucuaac acuaccuucc gaaguaaauu uaugcaacgu agacauauuu     1140

aaucccaaau acgacuguaa aauaaugacc ucaaaaacug augucucauc aucagucauu     1200

acaucacucg gagcaauagu caguugcuau ggaaaaacca aaugcacagc uaguaacaaa     1260

aacaggggua uaauaaaaac auuuucaaac ggaugcgauu acguaucaaa uaaaggagua     1320

gacaccguau ccguaggaaa uacucucuac ugcguaaaca aacaagaagg acaaucccua     1380

uacguaaaag gcgaaccaau cauuaacuuu uacgacccac uuguauuucc aucagacgaa     1440

uuugaugccu caauauccca agucaaugaa aaaauaaacc aaagucuagc auucauccga     1500

aaaucagaug aacuuuuaca caacguaaac gccggaaaau caacaacaaa caucaugauc     1560

acaacaauca ucauaguaau aauaguuaua cuacuuuccu uaauagcagu cggccuacua     1620

cucuacugca aagcacgauc cacaccagua accuuaucua aagaccaacu cucaggcaua     1680

aacaacauag cauucucaaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3232
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3232
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagca      120

aacgccauca caaccauccu cacagcaguc acuuucugcu ucgcauccgg acaaaacauc      180

acagaagagu ucuaucaauc cacgugcucc gcaguuucca aaggauaccu uggagccuua      240

cgaaccggcu gguacaccuc cgucaucacc auagaacuca gcaacaucaa agaaaucaaa      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaaaaac      360

gcagucaccg accuccaacu acucaugcaa ucaacccccg caaccggcuc cggcuccgcc      420

aucugcuccg gaguagccgu augcaaaguc cuccaccucg aaggcgaagu uaacaagauc      480

aaguccgcac uccuaucaac caacaaagca gucgucuccc uauccaacgg cgucuccgua      540

uuaacauuca aaguccucga ccucaaaaac uacauagaca aacagcuacu ccccauccua      600

aacaaacaau ccugcuccau ccccaacauc gaaacuguca ucgaguucca acagaaaaac      660

aaccgccucc uagaaaucac ccgagaguuc uccguaaacg ccggcgucac uacccccguc      720

ucuaccuaua ugcuaaccaa cucugaacuc cuaucccuaa ucaacgauau gcccauaacu      780

aacgaccaaa agaaacuuau guccaacaac guacaaauag uccggcaaca aucauacucu      840

aucaugugca ucaucaaaga agaaguacuu gccuacguug uccaacuccc acuauacggc      900

gucauagaca cuccaugcug gaaacuucac accucacccc ucugcaccac uaacacuaaa      960

gaaggcucua acaucugccu uacccgcacc gaccgcggau gguacugcga caacgcaggc     1020

ucaguuagcu ucuucccaca agccgaaacc ugcaaagucc agucaaaccg ugucuucugc     1080

gauaccauga acucgcucac ccucccuucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucaaaaaccg acguaucuuc uuccgucauc     1200

accucccucg gcgccaucgu auccugcuac ggcaaaacca aaugcacugc aucaaacaaa     1260

aaccgaggca ucaucaaaac cuucucgaac ggaugcgacu acguauccaa caagggcguc     1320

gacacagucu ccguugguaa cacccucuac ugcgucaaca aacaagaagg ccaaucccua     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cagugacgaa     1440

uuugacgccu ccaucuccca agucaacgaa aagaucaacc aaucccuugc cuucauacgc     1500

aaauccgacg aacuccuaca caacguuaac gccggaaaau caacaaccaa caucaugauc     1560

acaaccauca uaaucgucau aaucgucaua cuccucuccc ucauagccgu cggccugcua     1620

uuguacugua aagcccgcuc cacaccaguc acacuuucaa aagaccaacu cuccgggauc     1680

aacaacaucg ccuucuccaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3233
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3233
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3234
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3234
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3235
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3235
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3236
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3236
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gaucaauaac     1680

auugcauuca gcaauugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3237
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3237
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3238
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3238
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aaucaauaac     1680

aucgcuuuca gcaauugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3239
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3239
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacuaaa agccaaugcc      120

auaaccacua uucuaacagc aguaacauuc uguuucgccu caggacaaaa cauaacagaa      180

gaauuuuauc aauccaccug uuccgcaguc ucgaaaggcu accuuggcgc acuaagaacc      240

ggaugguaua caucaguaau aaccauugaa cuaucaaaua ucaaagaaau aaaaugcaac      300

ggaacugacg caaaagucaa acuaauaaaa caagaauuag acaaauacaa aaacgccguu      360

acagacuuac aacuacuaau gcaaucaacu ccagcaacag gaucaggauc ugcuauaugc      420

ucaggugucg ccguauguaa aguguuacac cucgaaggcg aaguaaacaa aauaaaauca      480

gcacuacuau ccacaaauaa agcaguagua ucacuaucca augguguauc aguacucaca      540

uucaaaguac uagacuuaaa aaauuauaua gauaaacaau uacuaccaau auuaaacaaa      600

caaucaugcu caauaccaaa cauagaaacc gucauugaau uucaacaaaa aaacaaucga      660

cuucuugaaa uaacacgaga auuuucagua aaugccggag uaacaacccc agucucaaca      720

uacauguuaa ccaacucuga acuccuaagc cuaaucaacg acaugcccau aacuaacgac      780

caaaaaaaac uaauguccaa uaauguccaa auaguaagac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccucgccuau guaguacaac uacccuuaua cggaguaauu      900

gacacaccau guuggaaacu acauacauca ccacuaugca ccacuaacac aaaagaaggc      960

uccaacauau gccuaacccg aacagaucgc ggaugguauu gcgacaacgc aggaagugua     1020

uccuucuuuc cacaagcaga aacaugcaaa guacaaucca acagaguauu cugugacacc     1080

augaacucuc uaacacuacc uuccgaagua aauuuaugca acguagacau auuuaauccc     1140

aaauacgacu guaaaauaau gaccucaaaa acugaugucu caucaucagu cauuacauca     1200

cucggagcaa uagucaguug cuauggaaaa accaaaugca cagcuaguaa caaaaacagg     1260

gguauaauaa aaacauuuuc aaacggaugc gauuacguau caaauaaagg aguagacacc     1320

guauccguag gaaauacucu cuacugcgua aacaaacaag aaggacaauc ccuauacgua     1380

aaaggcgaac caaucauuaa cuuuuacgac ccacuuguau uuccaucaga cgaauuugau     1440

gccucaauau cccaagucaa ugaaaaaaua aaccaaaguc uagcauucau ccgaaaauca     1500

gaugaacuuu uacacaacgu aaacgccgga aaaucaacaa caaacaucau gaucacaaca     1560

aucaucauag uaauaauagu uauacuacuu uccuuaauag cagucggccu acuacucuac     1620

ugcaaagcac gauccacacc aguaaccuua ucuaaagacc aacucucagg cauaaacaac     1680

auagcauucu caaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3240
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3240
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agcaaacgcc      120

aucacaacca uccucacagc agucacuuuc ugcuucgcau ccggacaaaa caucacagaa      180

gaguucuauc aauccacgug cuccgcaguu uccaaaggau accuuggagc cuuacgaacc      240

ggcugguaca ccuccgucau caccauagaa cucagcaaca ucaaagaaau caaaugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaccucc aacuacucau gcaaucaacc cccgcaaccg gcuccggcuc cgccaucugc      420

uccggaguag ccguaugcaa aguccuccac cucgaaggcg aaguuaacaa gaucaagucc      480

gcacuccuau caaccaacaa agcagucguc ucccuaucca acggcgucuc cguauuaaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaaacagc uacuccccau ccuaaacaaa      600

caauccugcu ccauccccaa caucgaaacu gucaucgagu uccaacagaa aaacaaccgc      660

cuccuagaaa ucacccgaga guucuccgua aacgccggcg ucacuacccc cgucucuacc      720

uauaugcuaa ccaacucuga acuccuaucc cuaaucaacg auaugcccau aacuaacgac      780

caaaagaaac uuauguccaa caacguacaa auaguccggc aacaaucaua cucuaucaug      840

ugcaucauca aagaagaagu acuugccuac guuguccaac ucccacuaua cggcgucaua      900

gacacuccau gcuggaaacu ucacaccuca ccccucugca ccacuaacac uaaagaaggc      960

ucuaacaucu gccuuacccg caccgaccgc ggaugguacu gcgacaacgc aggcucaguu     1020

agcuucuucc cacaagccga aaccugcaaa guccagucaa accgugucuu cugcgauacc     1080

augaacucgc ucacccuccc uuccgaaguc aaccucugca acgucgacau cuucaacccc     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacguau cuucuuccgu caucaccucc     1200

cucggcgcca ucguauccug cuacggcaaa accaaaugca cugcaucaaa caaaaaccga     1260

ggcaucauca aaaccuucuc gaacggaugc gacuacguau ccaacaaggg cgucgacaca     1320

gucuccguug guaacacccu cuacugcguc aacaaacaag aaggccaauc ccuauacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccaguga cgaauuugac     1440

gccuccaucu cccaagucaa cgaaaagauc aaccaauccc uugccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu uaacgccgga aaaucaacaa ccaacaucau gaucacaacc     1560

aucauaaucg ucauaaucgu cauacuccuc ucccucauag ccgucggccu gcuauuguac     1620

uguaaagccc gcuccacacc agucacacuu ucaaaagacc aacucuccgg gaucaacaac     1680

aucgccuucu ccaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3241
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3241
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3242
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3242
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3243
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3243
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3244
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3244
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

aucaauaaca uugcauucag caauugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3245
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3245
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3246
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3246
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

aucaauaaca ucgcuuucag caauugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3247
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3247
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacuaaaa      120

gccaaugcca uaaccacuau ucuaacagca guaacauucu guuucgccuc aggacaaaac      180

auaacagaag aauuuuauca auccaccugu uccgcagucu cgaaaggcua ccuuggcgca      240

cuaagaaccg gaugguauac aucaguaaua accauugaac uaucaaauau caaagaaaua      300

aaaugcaacg gaacugacgc aaaagucaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgccguua cagacuuaca acuacuaaug caaucaacuc cagcaacagg aucaggaucu      420

gcuauaugcu caggugucgc cguauguaaa guguuacacc ucgaaggcga aguaaacaaa      480

auaaaaucag cacuacuauc cacaaauaaa gcaguaguau cacuauccaa ugguguauca      540

guacucacau ucaaaguacu agacuuaaaa aauuauauag auaaacaauu acuaccaaua      600

uuaaacaaac aaucaugcuc aauaccaaac auagaaaccg ucauugaauu ucaacaaaaa      660

aacaaucgac uucuugaaau aacacgagaa uuuucaguaa augccggagu aacaacccca      720

gucucaacau acauguuaac caacucugaa cuccuaagcc uaaucaacga caugcccaua      780

acuaacgacc aaaaaaaacu aauguccaau aauguccaaa uaguaagaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cucgccuaug uaguacaacu acccuuauac      900

ggaguaauug acacaccaug uuggaaacua cauacaucac cacuaugcac cacuaacaca      960

aaagaaggcu ccaacauaug ccuaacccga acagaucgcg gaugguauug cgacaacgca     1020

ggaaguguau ccuucuuucc acaagcagaa acaugcaaag uacaauccaa cagaguauuc     1080

ugugacacca ugaacucucu aacacuaccu uccgaaguaa auuuaugcaa cguagacaua     1140

uuuaauccca aauacgacug uaaaauaaug accucaaaaa cugaugucuc aucaucaguc     1200

auuacaucac ucggagcaau agucaguugc uauggaaaaa ccaaaugcac agcuaguaac     1260

aaaaacaggg guauaauaaa aacauuuuca aacggaugcg auuacguauc aaauaaagga     1320

guagacaccg uauccguagg aaauacucuc uacugcguaa acaaacaaga aggacaaucc     1380

cuauacguaa aaggcgaacc aaucauuaac uuuuacgacc cacuuguauu uccaucagac     1440

gaauuugaug ccucaauauc ccaagucaau gaaaaaauaa accaaagucu agcauucauc     1500

cgaaaaucag augaacuuuu acacaacgua aacgccggaa aaucaacaac aaacaucaug     1560

aucacaacaa ucaucauagu aauaauaguu auacuacuuu ccuuaauagc agucggccua     1620

cuacucuacu gcaaagcacg auccacacca guaaccuuau cuaaagacca acucucaggc     1680

auaaacaaca uagcauucuc aaacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3248
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3248
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gcaaacgcca ucacaaccau ccucacagca gucacuuucu gcuucgcauc cggacaaaac      180

aucacagaag aguucuauca auccacgugc uccgcaguuu ccaaaggaua ccuuggagcc      240

uuacgaaccg gcugguacac cuccgucauc accauagaac ucagcaacau caaagaaauc      300

aaaugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaccucca acuacucaug caaucaaccc ccgcaaccgg cuccggcucc      420

gccaucugcu ccggaguagc cguaugcaaa guccuccacc ucgaaggcga aguuaacaag      480

aucaaguccg cacuccuauc aaccaacaaa gcagucgucu cccuauccaa cggcgucucc      540

guauuaacau ucaaaguccu cgaccucaaa aacuacauag acaaacagcu acuccccauc      600

cuaaacaaac aauccugcuc cauccccaac aucgaaacug ucaucgaguu ccaacagaaa      660

aacaaccgcc uccuagaaau cacccgagag uucuccguaa acgccggcgu cacuaccccc      720

gucucuaccu auaugcuaac caacucugaa cuccuauccc uaaucaacga uaugcccaua      780

acuaacgacc aaaagaaacu uauguccaac aacguacaaa uaguccggca acaaucauac      840

ucuaucaugu gcaucaucaa agaagaagua cuugccuacg uuguccaacu cccacuauac      900

ggcgucauag acacuccaug cuggaaacuu cacaccucac cccucugcac cacuaacacu      960

aaagaaggcu cuaacaucug ccuuacccgc accgaccgcg gaugguacug cgacaacgca     1020

ggcucaguua gcuucuuccc acaagccgaa accugcaaag uccagucaaa ccgugucuuc     1080

ugcgauacca ugaacucgcu cacccucccu uccgaaguca accucugcaa cgucgacauc     1140

uucaacccca aauacgacug caaaaucaug accucaaaaa ccgacguauc uucuuccguc     1200

aucaccuccc ucggcgccau cguauccugc uacggcaaaa ccaaaugcac ugcaucaaac     1260

aaaaaccgag gcaucaucaa aaccuucucg aacggaugcg acuacguauc caacaagggc     1320

gucgacacag ucuccguugg uaacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cuauacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagugac     1440

gaauuugacg ccuccaucuc ccaagucaac gaaaagauca accaaucccu ugccuucaua     1500

cgcaaauccg acgaacuccu acacaacguu aacgccggaa aaucaacaac caacaucaug     1560

aucacaacca ucauaaucgu cauaaucguc auacuccucu cccucauagc cgucggccug     1620

cuauuguacu guaaagcccg cuccacacca gucacacuuu caaaagacca acucuccggg     1680

aucaacaaca ucgccuucuc caacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3249
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3249
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3250
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3250
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3251
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3251
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3252
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3252
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gaucaauaac     1680

auugcauuca gcaauugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3253
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3253
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3254
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3254
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aaucaauaac     1680

aucgcuuuca gcaauugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3255
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3255
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacuaaa agccaaugcc      120

auaaccacua uucuaacagc aguaacauuc uguuucgccu caggacaaaa cauaacagaa      180

gaauuuuauc aauccaccug uuccgcaguc ucgaaaggcu accuuggcgc acuaagaacc      240

ggaugguaua caucaguaau aaccauugaa cuaucaaaua ucaaagaaau aaaaugcaac      300

ggaacugacg caaaagucaa acuaauaaaa caagaauuag acaaauacaa aaacgccguu      360

acagacuuac aacuacuaau gcaaucaacu ccagcaacag gaucaggauc ugcuauaugc      420

ucaggugucg ccguauguaa aguguuacac cucgaaggcg aaguaaacaa aauaaaauca      480

gcacuacuau ccacaaauaa agcaguagua ucacuaucca augguguauc aguacucaca      540

uucaaaguac uagacuuaaa aaauuauaua gauaaacaau uacuaccaau auuaaacaaa      600

caaucaugcu caauaccaaa cauagaaacc gucauugaau uucaacaaaa aaacaaucga      660

cuucuugaaa uaacacgaga auuuucagua aaugccggag uaacaacccc agucucaaca      720

uacauguuaa ccaacucuga acuccuaagc cuaaucaacg acaugcccau aacuaacgac      780

caaaaaaaac uaauguccaa uaauguccaa auaguaagac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccucgccuau guaguacaac uacccuuaua cggaguaauu      900

gacacaccau guuggaaacu acauacauca ccacuaugca ccacuaacac aaaagaaggc      960

uccaacauau gccuaacccg aacagaucgc ggaugguauu gcgacaacgc aggaagugua     1020

uccuucuuuc cacaagcaga aacaugcaaa guacaaucca acagaguauu cugugacacc     1080

augaacucuc uaacacuacc uuccgaagua aauuuaugca acguagacau auuuaauccc     1140

aaauacgacu guaaaauaau gaccucaaaa acugaugucu caucaucagu cauuacauca     1200

cucggagcaa uagucaguug cuauggaaaa accaaaugca cagcuaguaa caaaaacagg     1260

gguauaauaa aaacauuuuc aaacggaugc gauuacguau caaauaaagg aguagacacc     1320

guauccguag gaaauacucu cuacugcgua aacaaacaag aaggacaauc ccuauacgua     1380

aaaggcgaac caaucauuaa cuuuuacgac ccacuuguau uuccaucaga cgaauuugau     1440

gccucaauau cccaagucaa ugaaaaaaua aaccaaaguc uagcauucau ccgaaaauca     1500

gaugaacuuu uacacaacgu aaacgccgga aaaucaacaa caaacaucau gaucacaaca     1560

aucaucauag uaauaauagu uauacuacuu uccuuaauag cagucggccu acuacucuac     1620

ugcaaagcac gauccacacc aguaaccuua ucuaaagacc aacucucagg cauaaacaac     1680

auagcauucu caaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3256
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3256
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agcaaacgcc      120

aucacaacca uccucacagc agucacuuuc ugcuucgcau ccggacaaaa caucacagaa      180

gaguucuauc aauccacgug cuccgcaguu uccaaaggau accuuggagc cuuacgaacc      240

ggcugguaca ccuccgucau caccauagaa cucagcaaca ucaaagaaau caaaugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaccucc aacuacucau gcaaucaacc cccgcaaccg gcuccggcuc cgccaucugc      420

uccggaguag ccguaugcaa aguccuccac cucgaaggcg aaguuaacaa gaucaagucc      480

gcacuccuau caaccaacaa agcagucguc ucccuaucca acggcgucuc cguauuaaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaaacagc uacuccccau ccuaaacaaa      600

caauccugcu ccauccccaa caucgaaacu gucaucgagu uccaacagaa aaacaaccgc      660

cuccuagaaa ucacccgaga guucuccgua aacgccggcg ucacuacccc cgucucuacc      720

uauaugcuaa ccaacucuga acuccuaucc cuaaucaacg auaugcccau aacuaacgac      780

caaaagaaac uuauguccaa caacguacaa auaguccggc aacaaucaua cucuaucaug      840

ugcaucauca aagaagaagu acuugccuac guuguccaac ucccacuaua cggcgucaua      900

gacacuccau gcuggaaacu ucacaccuca ccccucugca ccacuaacac uaaagaaggc      960

ucuaacaucu gccuuacccg caccgaccgc ggaugguacu gcgacaacgc aggcucaguu     1020

agcuucuucc cacaagccga aaccugcaaa guccagucaa accgugucuu cugcgauacc     1080

augaacucgc ucacccuccc uuccgaaguc aaccucugca acgucgacau cuucaacccc     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacguau cuucuuccgu caucaccucc     1200

cucggcgcca ucguauccug cuacggcaaa accaaaugca cugcaucaaa caaaaaccga     1260

ggcaucauca aaaccuucuc gaacggaugc gacuacguau ccaacaaggg cgucgacaca     1320

gucuccguug guaacacccu cuacugcguc aacaaacaag aaggccaauc ccuauacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccaguga cgaauuugac     1440

gccuccaucu cccaagucaa cgaaaagauc aaccaauccc uugccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu uaacgccgga aaaucaacaa ccaacaucau gaucacaacc     1560

aucauaaucg ucauaaucgu cauacuccuc ucccucauag ccgucggccu gcuauuguac     1620

uguaaagccc gcuccacacc agucacacuu ucaaaagacc aacucuccgg gaucaacaac     1680

aucgccuucu ccaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3257
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3257
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3258
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3258
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3259
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3259
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3260
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3260
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggaucaa uaacauugca uucagcaauu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3261
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3261
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3262
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3262
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaaucaa uaacaucgcu uucagcaauu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3263
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3263
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac uaaaagccaa ugccauaacc acuauucuaa cagcaguaac auucuguuuc      240

gccucaggac aaaacauaac agaagaauuu uaucaaucca ccuguuccgc agucucgaaa      300

ggcuaccuug gcgcacuaag aaccggaugg uauacaucag uaauaaccau ugaacuauca      360

aauaucaaag aaauaaaaug caacggaacu gacgcaaaag ucaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc cguuacagac uuacaacuac uaaugcaauc aacuccagca      480

acaggaucag gaucugcuau augcucaggu gucgccguau guaaaguguu acaccucgaa      540

ggcgaaguaa acaaaauaaa aucagcacua cuauccacaa auaaagcagu aguaucacua      600

uccaauggug uaucaguacu cacauucaaa guacuagacu uaaaaaauua uauagauaaa      660

caauuacuac caauauuaaa caaacaauca ugcucaauac caaacauaga aaccgucauu      720

gaauuucaac aaaaaaacaa ucgacuucuu gaaauaacac gagaauuuuc aguaaaugcc      780

ggaguaacaa ccccagucuc aacauacaug uuaaccaacu cugaacuccu aagccuaauc      840

aacgacaugc ccauaacuaa cgaccaaaaa aaacuaaugu ccaauaaugu ccaaauagua      900

agacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccucgc cuauguagua      960

caacuacccu uauacggagu aauugacaca ccauguugga aacuacauac aucaccacua     1020

ugcaccacua acacaaaaga aggcuccaac auaugccuaa cccgaacaga ucgcggaugg     1080

uauugcgaca acgcaggaag uguauccuuc uuuccacaag cagaaacaug caaaguacaa     1140

uccaacagag uauucuguga caccaugaac ucucuaacac uaccuuccga aguaaauuua     1200

ugcaacguag acauauuuaa ucccaaauac gacuguaaaa uaaugaccuc aaaaacugau     1260

gucucaucau cagucauuac aucacucgga gcaauaguca guugcuaugg aaaaaccaaa     1320

ugcacagcua guaacaaaaa cagggguaua auaaaaacau uuucaaacgg augcgauuac     1380

guaucaaaua aaggaguaga caccguaucc guaggaaaua cucucuacug cguaaacaaa     1440

caagaaggac aaucccuaua cguaaaaggc gaaccaauca uuaacuuuua cgacccacuu     1500

guauuuccau cagacgaauu ugaugccuca auaucccaag ucaaugaaaa aauaaaccaa     1560

agucuagcau ucauccgaaa aucagaugaa cuuuuacaca acguaaacgc cggaaaauca     1620

acaacaaaca ucaugaucac aacaaucauc auaguaauaa uaguuauacu acuuuccuua     1680

auagcagucg gccuacuacu cuacugcaaa gcacgaucca caccaguaac cuuaucuaaa     1740

gaccaacucu caggcauaaa caacauagca uucucaaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3264
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3264
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagcaaa cgccaucaca accauccuca cagcagucac uuucugcuuc      240

gcauccggac aaaacaucac agaagaguuc uaucaaucca cgugcuccgc aguuuccaaa      300

ggauaccuug gagccuuacg aaccggcugg uacaccuccg ucaucaccau agaacucagc      360

aacaucaaag aaaucaaaug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaacgc agucaccgac cuccaacuac ucaugcaauc aacccccgca      480

accggcuccg gcuccgccau cugcuccgga guagccguau gcaaaguccu ccaccucgaa      540

ggcgaaguua acaagaucaa guccgcacuc cuaucaacca acaaagcagu cgucucccua      600

uccaacggcg ucuccguauu aacauucaaa guccucgacc ucaaaaacua cauagacaaa      660

cagcuacucc ccauccuaaa caaacaaucc ugcuccaucc ccaacaucga aacugucauc      720

gaguuccaac agaaaaacaa ccgccuccua gaaaucaccc gagaguucuc cguaaacgcc      780

ggcgucacua cccccgucuc uaccuauaug cuaaccaacu cugaacuccu aucccuaauc      840

aacgauaugc ccauaacuaa cgaccaaaag aaacuuaugu ccaacaacgu acaaauaguc      900

cggcaacaau cauacucuau caugugcauc aucaaagaag aaguacuugc cuacguuguc      960

caacucccac uauacggcgu cauagacacu ccaugcugga aacuucacac cucaccccuc     1020

ugcaccacua acacuaaaga aggcucuaac aucugccuua cccgcaccga ccgcggaugg     1080

uacugcgaca acgcaggcuc aguuagcuuc uucccacaag ccgaaaccug caaaguccag     1140

ucaaaccgug ucuucugcga uaccaugaac ucgcucaccc ucccuuccga agucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

guaucuucuu ccgucaucac cucccucggc gccaucguau ccugcuacgg caaaaccaaa     1320

ugcacugcau caaacaaaaa ccgaggcauc aucaaaaccu ucucgaacgg augcgacuac     1380

guauccaaca agggcgucga cacagucucc guugguaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccuaua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuucccca gugacgaauu ugacgccucc aucucccaag ucaacgaaaa gaucaaccaa     1560

ucccuugccu ucauacgcaa auccgacgaa cuccuacaca acguuaacgc cggaaaauca     1620

acaaccaaca ucaugaucac aaccaucaua aucgucauaa ucgucauacu ccucucccuc     1680

auagccgucg gccugcuauu guacuguaaa gcccgcucca caccagucac acuuucaaaa     1740

gaccaacucu ccgggaucaa caacaucgcc uucuccaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3265
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3265
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3266
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3266
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3267
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3267
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3268
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3268
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau caauaacauu gcauucagca     1680

auugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3269
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3269
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3270
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3270
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau caauaacauc gcuuucagca     1680

auugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3271
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3271
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacuaaaagc caaugccaua accacuauuc      120

uaacagcagu aacauucugu uucgccucag gacaaaacau aacagaagaa uuuuaucaau      180

ccaccuguuc cgcagucucg aaaggcuacc uuggcgcacu aagaaccgga ugguauacau      240

caguaauaac cauugaacua ucaaauauca aagaaauaaa augcaacgga acugacgcaa      300

aagucaaacu aauaaaacaa gaauuagaca aauacaaaaa cgccguuaca gacuuacaac      360

uacuaaugca aucaacucca gcaacaggau caggaucugc uauaugcuca ggugucgccg      420

uauguaaagu guuacaccuc gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca      480

caaauaaagc aguaguauca cuauccaaug guguaucagu acucacauuc aaaguacuag      540

acuuaaaaaa uuauauagau aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa      600

uaccaaacau agaaaccguc auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa      660

cacgagaauu uucaguaaau gccggaguaa caaccccagu cucaacauac auguuaacca      720

acucugaacu ccuaagccua aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa      780

uguccaauaa uguccaaaua guaagacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu cgccuaugua guacaacuac ccuuauacgg aguaauugac acaccauguu      900

ggaaacuaca uacaucacca cuaugcacca cuaacacaaa agaaggcucc aacauaugcc      960

uaacccgaac agaucgcgga ugguauugcg acaacgcagg aaguguaucc uucuuuccac     1020

aagcagaaac augcaaagua caauccaaca gaguauucug ugacaccaug aacucucuaa     1080

cacuaccuuc cgaaguaaau uuaugcaacg uagacauauu uaaucccaaa uacgacugua     1140

aaauaaugac cucaaaaacu gaugucucau caucagucau uacaucacuc ggagcaauag     1200

ucaguugcua uggaaaaacc aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa     1260

cauuuucaaa cggaugcgau uacguaucaa auaaaggagu agacaccgua uccguaggaa     1320

auacucucua cugcguaaac aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa     1380

ucauuaacuu uuacgaccca cuuguauuuc caucagacga auuugaugcc ucaauauccc     1440

aagucaauga aaaaauaaac caaagucuag cauucauccg aaaaucagau gaacuuuuac     1500

acaacguaaa cgccggaaaa ucaacaacaa acaucaugau cacaacaauc aucauaguaa     1560

uaauaguuau acuacuuucc uuaauagcag ucggccuacu acucuacugc aaagcacgau     1620

ccacaccagu aaccuuaucu aaagaccaac ucucaggcau aaacaacaua gcauucucaa     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3272
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3272
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc aaacgccauc acaaccaucc      120

ucacagcagu cacuuucugc uucgcauccg gacaaaacau cacagaagag uucuaucaau      180

ccacgugcuc cgcaguuucc aaaggauacc uuggagccuu acgaaccggc ugguacaccu      240

ccgucaucac cauagaacuc agcaacauca aagaaaucaa augcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa cgcagucacc gaccuccaac      360

uacucaugca aucaaccccc gcaaccggcu ccggcuccgc caucugcucc ggaguagccg      420

uaugcaaagu ccuccaccuc gaaggcgaag uuaacaagau caaguccgca cuccuaucaa      480

ccaacaaagc agucgucucc cuauccaacg gcgucuccgu auuaacauuc aaaguccucg      540

accucaaaaa cuacauagac aaacagcuac uccccauccu aaacaaacaa uccugcucca      600

uccccaacau cgaaacuguc aucgaguucc aacagaaaaa caaccgccuc cuagaaauca      660

cccgagaguu cuccguaaac gccggcguca cuacccccgu cucuaccuau augcuaacca      720

acucugaacu ccuaucccua aucaacgaua ugcccauaac uaacgaccaa aagaaacuua      780

uguccaacaa cguacaaaua guccggcaac aaucauacuc uaucaugugc aucaucaaag      840

aagaaguacu ugccuacguu guccaacucc cacuauacgg cgucauagac acuccaugcu      900

ggaaacuuca caccucaccc cucugcacca cuaacacuaa agaaggcucu aacaucugcc      960

uuacccgcac cgaccgcgga ugguacugcg acaacgcagg cucaguuagc uucuucccac     1020

aagccgaaac cugcaaaguc cagucaaacc gugucuucug cgauaccaug aacucgcuca     1080

cccucccuuc cgaagucaac cucugcaacg ucgacaucuu caaccccaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacguaucuu cuuccgucau caccucccuc ggcgccaucg     1200

uauccugcua cggcaaaacc aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa     1260

ccuucucgaa cggaugcgac uacguaucca acaagggcgu cgacacaguc uccguuggua     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu auacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccagugacga auuugacgcc uccaucuccc     1440

aagucaacga aaagaucaac caaucccuug ccuucauacg caaauccgac gaacuccuac     1500

acaacguuaa cgccggaaaa ucaacaacca acaucaugau cacaaccauc auaaucguca     1560

uaaucgucau acuccucucc cucauagccg ucggccugcu auuguacugu aaagcccgcu     1620

ccacaccagu cacacuuuca aaagaccaac ucuccgggau caacaacauc gccuucucca     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  3273
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3273
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3274
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3274
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3275
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3275
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3276
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3276
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggaucaa uaacauugca uucagcaauu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3277
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3277
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3278
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3278
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaaucaa uaacaucgcu uucagcaauu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3279
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3279
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac uaaaagccaa ugccauaacc acuauucuaa cagcaguaac auucuguuuc      240

gccucaggac aaaacauaac agaagaauuu uaucaaucca ccuguuccgc agucucgaaa      300

ggcuaccuug gcgcacuaag aaccggaugg uauacaucag uaauaaccau ugaacuauca      360

aauaucaaag aaauaaaaug caacggaacu gacgcaaaag ucaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc cguuacagac uuacaacuac uaaugcaauc aacuccagca      480

acaggaucag gaucugcuau augcucaggu gucgccguau guaaaguguu acaccucgaa      540

ggcgaaguaa acaaaauaaa aucagcacua cuauccacaa auaaagcagu aguaucacua      600

uccaauggug uaucaguacu cacauucaaa guacuagacu uaaaaaauua uauagauaaa      660

caauuacuac caauauuaaa caaacaauca ugcucaauac caaacauaga aaccgucauu      720

gaauuucaac aaaaaaacaa ucgacuucuu gaaauaacac gagaauuuuc aguaaaugcc      780

ggaguaacaa ccccagucuc aacauacaug uuaaccaacu cugaacuccu aagccuaauc      840

aacgacaugc ccauaacuaa cgaccaaaaa aaacuaaugu ccaauaaugu ccaaauagua      900

agacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccucgc cuauguagua      960

caacuacccu uauacggagu aauugacaca ccauguugga aacuacauac aucaccacua     1020

ugcaccacua acacaaaaga aggcuccaac auaugccuaa cccgaacaga ucgcggaugg     1080

uauugcgaca acgcaggaag uguauccuuc uuuccacaag cagaaacaug caaaguacaa     1140

uccaacagag uauucuguga caccaugaac ucucuaacac uaccuuccga aguaaauuua     1200

ugcaacguag acauauuuaa ucccaaauac gacuguaaaa uaaugaccuc aaaaacugau     1260

gucucaucau cagucauuac aucacucgga gcaauaguca guugcuaugg aaaaaccaaa     1320

ugcacagcua guaacaaaaa cagggguaua auaaaaacau uuucaaacgg augcgauuac     1380

guaucaaaua aaggaguaga caccguaucc guaggaaaua cucucuacug cguaaacaaa     1440

caagaaggac aaucccuaua cguaaaaggc gaaccaauca uuaacuuuua cgacccacuu     1500

guauuuccau cagacgaauu ugaugccuca auaucccaag ucaaugaaaa aauaaaccaa     1560

agucuagcau ucauccgaaa aucagaugaa cuuuuacaca acguaaacgc cggaaaauca     1620

acaacaaaca ucaugaucac aacaaucauc auaguaauaa uaguuauacu acuuuccuua     1680

auagcagucg gccuacuacu cuacugcaaa gcacgaucca caccaguaac cuuaucuaaa     1740

gaccaacucu caggcauaaa caacauagca uucucaaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3280
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3280
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagcaaa cgccaucaca accauccuca cagcagucac uuucugcuuc      240

gcauccggac aaaacaucac agaagaguuc uaucaaucca cgugcuccgc aguuuccaaa      300

ggauaccuug gagccuuacg aaccggcugg uacaccuccg ucaucaccau agaacucagc      360

aacaucaaag aaaucaaaug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaacgc agucaccgac cuccaacuac ucaugcaauc aacccccgca      480

accggcuccg gcuccgccau cugcuccgga guagccguau gcaaaguccu ccaccucgaa      540

ggcgaaguua acaagaucaa guccgcacuc cuaucaacca acaaagcagu cgucucccua      600

uccaacggcg ucuccguauu aacauucaaa guccucgacc ucaaaaacua cauagacaaa      660

cagcuacucc ccauccuaaa caaacaaucc ugcuccaucc ccaacaucga aacugucauc      720

gaguuccaac agaaaaacaa ccgccuccua gaaaucaccc gagaguucuc cguaaacgcc      780

ggcgucacua cccccgucuc uaccuauaug cuaaccaacu cugaacuccu aucccuaauc      840

aacgauaugc ccauaacuaa cgaccaaaag aaacuuaugu ccaacaacgu acaaauaguc      900

cggcaacaau cauacucuau caugugcauc aucaaagaag aaguacuugc cuacguuguc      960

caacucccac uauacggcgu cauagacacu ccaugcugga aacuucacac cucaccccuc     1020

ugcaccacua acacuaaaga aggcucuaac aucugccuua cccgcaccga ccgcggaugg     1080

uacugcgaca acgcaggcuc aguuagcuuc uucccacaag ccgaaaccug caaaguccag     1140

ucaaaccgug ucuucugcga uaccaugaac ucgcucaccc ucccuuccga agucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

guaucuucuu ccgucaucac cucccucggc gccaucguau ccugcuacgg caaaaccaaa     1320

ugcacugcau caaacaaaaa ccgaggcauc aucaaaaccu ucucgaacgg augcgacuac     1380

guauccaaca agggcgucga cacagucucc guugguaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccuaua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuucccca gugacgaauu ugacgccucc aucucccaag ucaacgaaaa gaucaaccaa     1560

ucccuugccu ucauacgcaa auccgacgaa cuccuacaca acguuaacgc cggaaaauca     1620

acaaccaaca ucaugaucac aaccaucaua aucgucauaa ucgucauacu ccucucccuc     1680

auagccgucg gccugcuauu guacuguaaa gcccgcucca caccagucac acuuucaaaa     1740

gaccaacucu ccgggaucaa caacaucgcc uucuccaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3281
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3281
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3282
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3282
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      540

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1380

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1680

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3283
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3283
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3284
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3284
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      360

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      480

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      540

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      600

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      660

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      720

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      780

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      840

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua      900

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc      960

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg     1020

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1080

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1140

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1200

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1260

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1320

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1380

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1440

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1500

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1560

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1620

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1680

aaagaucaac ucucugggau caauaacauu gcauucagca auugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3285
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3285
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3286
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3286
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      360

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      480

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      540

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      600

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      660

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      720

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      780

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      840

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug      900

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      960

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc     1020

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1080

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1140

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1200

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1260

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1320

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1380

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1440

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1500

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1560

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1620

cugauugccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1680

aaagaucaac ucuccggaau caauaacauc gcuuucagca auugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3287
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3287
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaauuacuca uacuaaaagc caaugccaua accacuauuc uaacagcagu aacauucugu      180

uucgccucag gacaaaacau aacagaagaa uuuuaucaau ccaccuguuc cgcagucucg      240

aaaggcuacc uuggcgcacu aagaaccgga ugguauacau caguaauaac cauugaacua      300

ucaaauauca aagaaauaaa augcaacgga acugacgcaa aagucaaacu aauaaaacaa      360

gaauuagaca aauacaaaaa cgccguuaca gacuuacaac uacuaaugca aucaacucca      420

gcaacaggau caggaucugc uauaugcuca ggugucgccg uauguaaagu guuacaccuc      480

gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca caaauaaagc aguaguauca      540

cuauccaaug guguaucagu acucacauuc aaaguacuag acuuaaaaaa uuauauagau      600

aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa uaccaaacau agaaaccguc      660

auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa cacgagaauu uucaguaaau      720

gccggaguaa caaccccagu cucaacauac auguuaacca acucugaacu ccuaagccua      780

aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa uguccaauaa uguccaaaua      840

guaagacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu cgccuaugua      900

guacaacuac ccuuauacgg aguaauugac acaccauguu ggaaacuaca uacaucacca      960

cuaugcacca cuaacacaaa agaaggcucc aacauaugcc uaacccgaac agaucgcgga     1020

ugguauugcg acaacgcagg aaguguaucc uucuuuccac aagcagaaac augcaaagua     1080

caauccaaca gaguauucug ugacaccaug aacucucuaa cacuaccuuc cgaaguaaau     1140

uuaugcaacg uagacauauu uaaucccaaa uacgacugua aaauaaugac cucaaaaacu     1200

gaugucucau caucagucau uacaucacuc ggagcaauag ucaguugcua uggaaaaacc     1260

aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa cauuuucaaa cggaugcgau     1320

uacguaucaa auaaaggagu agacaccgua uccguaggaa auacucucua cugcguaaac     1380

aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa ucauuaacuu uuacgaccca     1440

cuuguauuuc caucagacga auuugaugcc ucaauauccc aagucaauga aaaaauaaac     1500

caaagucuag cauucauccg aaaaucagau gaacuuuuac acaacguaaa cgccggaaaa     1560

ucaacaacaa acaucaugau cacaacaauc aucauaguaa uaauaguuau acuacuuucc     1620

uuaauagcag ucggccuacu acucuacugc aaagcacgau ccacaccagu aaccuuaucu     1680

aaagaccaac ucucaggcau aaacaacaua gcauucucaa acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3288
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3288
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccuuaaagc aaacgccauc acaaccaucc ucacagcagu cacuuucugc      180

uucgcauccg gacaaaacau cacagaagag uucuaucaau ccacgugcuc cgcaguuucc      240

aaaggauacc uuggagccuu acgaaccggc ugguacaccu ccgucaucac cauagaacuc      300

agcaacauca aagaaaucaa augcaacgga accgacgcaa aagucaaacu caucaaacaa      360

gaacuagaca aauacaaaaa cgcagucacc gaccuccaac uacucaugca aucaaccccc      420

gcaaccggcu ccggcuccgc caucugcucc ggaguagccg uaugcaaagu ccuccaccuc      480

gaaggcgaag uuaacaagau caaguccgca cuccuaucaa ccaacaaagc agucgucucc      540

cuauccaacg gcgucuccgu auuaacauuc aaaguccucg accucaaaaa cuacauagac      600

aaacagcuac uccccauccu aaacaaacaa uccugcucca uccccaacau cgaaacuguc      660

aucgaguucc aacagaaaaa caaccgccuc cuagaaauca cccgagaguu cuccguaaac      720

gccggcguca cuacccccgu cucuaccuau augcuaacca acucugaacu ccuaucccua      780

aucaacgaua ugcccauaac uaacgaccaa aagaaacuua uguccaacaa cguacaaaua      840

guccggcaac aaucauacuc uaucaugugc aucaucaaag aagaaguacu ugccuacguu      900

guccaacucc cacuauacgg cgucauagac acuccaugcu ggaaacuuca caccucaccc      960

cucugcacca cuaacacuaa agaaggcucu aacaucugcc uuacccgcac cgaccgcgga     1020

ugguacugcg acaacgcagg cucaguuagc uucuucccac aagccgaaac cugcaaaguc     1080

cagucaaacc gugucuucug cgauaccaug aacucgcuca cccucccuuc cgaagucaac     1140

cucugcaacg ucgacaucuu caaccccaaa uacgacugca aaaucaugac cucaaaaacc     1200

gacguaucuu cuuccgucau caccucccuc ggcgccaucg uauccugcua cggcaaaacc     1260

aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa ccuucucgaa cggaugcgac     1320

uacguaucca acaagggcgu cgacacaguc uccguuggua acacccucua cugcgucaac     1380

aaacaagaag gccaaucccu auacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccagugacga auuugacgcc uccaucuccc aagucaacga aaagaucaac     1500

caaucccuug ccuucauacg caaauccgac gaacuccuac acaacguuaa cgccggaaaa     1560

ucaacaacca acaucaugau cacaaccauc auaaucguca uaaucgucau acuccucucc     1620

cucauagccg ucggccugcu auuguacugu aaagcccgcu ccacaccagu cacacuuuca     1680

aaagaccaac ucuccgggau caacaacauc gccuucucca acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  3289
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3289
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3290
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3290
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3291
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3291
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3292
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3292
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

aucaauaaca uugcauucag caauugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3293
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3293
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3294
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3294
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

aucaauaaca ucgcuuucag caauugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3295
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3295
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacuaaaa      120

gccaaugcca uaaccacuau ucuaacagca guaacauucu guuucgccuc aggacaaaac      180

auaacagaag aauuuuauca auccaccugu uccgcagucu cgaaaggcua ccuuggcgca      240

cuaagaaccg gaugguauac aucaguaaua accauugaac uaucaaauau caaagaaaua      300

aaaugcaacg gaacugacgc aaaagucaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgccguua cagacuuaca acuacuaaug caaucaacuc cagcaacagg aucaggaucu      420

gcuauaugcu caggugucgc cguauguaaa guguuacacc ucgaaggcga aguaaacaaa      480

auaaaaucag cacuacuauc cacaaauaaa gcaguaguau cacuauccaa ugguguauca      540

guacucacau ucaaaguacu agacuuaaaa aauuauauag auaaacaauu acuaccaaua      600

uuaaacaaac aaucaugcuc aauaccaaac auagaaaccg ucauugaauu ucaacaaaaa      660

aacaaucgac uucuugaaau aacacgagaa uuuucaguaa augccggagu aacaacccca      720

gucucaacau acauguuaac caacucugaa cuccuaagcc uaaucaacga caugcccaua      780

acuaacgacc aaaaaaaacu aauguccaau aauguccaaa uaguaagaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cucgccuaug uaguacaacu acccuuauac      900

ggaguaauug acacaccaug uuggaaacua cauacaucac cacuaugcac cacuaacaca      960

aaagaaggcu ccaacauaug ccuaacccga acagaucgcg gaugguauug cgacaacgca     1020

ggaaguguau ccuucuuucc acaagcagaa acaugcaaag uacaauccaa cagaguauuc     1080

ugugacacca ugaacucucu aacacuaccu uccgaaguaa auuuaugcaa cguagacaua     1140

uuuaauccca aauacgacug uaaaauaaug accucaaaaa cugaugucuc aucaucaguc     1200

auuacaucac ucggagcaau agucaguugc uauggaaaaa ccaaaugcac agcuaguaac     1260

aaaaacaggg guauaauaaa aacauuuuca aacggaugcg auuacguauc aaauaaagga     1320

guagacaccg uauccguagg aaauacucuc uacugcguaa acaaacaaga aggacaaucc     1380

cuauacguaa aaggcgaacc aaucauuaac uuuuacgacc cacuuguauu uccaucagac     1440

gaauuugaug ccucaauauc ccaagucaau gaaaaaauaa accaaagucu agcauucauc     1500

cgaaaaucag augaacuuuu acacaacgua aacgccggaa aaucaacaac aaacaucaug     1560

aucacaacaa ucaucauagu aauaauaguu auacuacuuu ccuuaauagc agucggccua     1620

cuacucuacu gcaaagcacg auccacacca guaaccuuau cuaaagacca acucucaggc     1680

auaaacaaca uagcauucuc aaacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3296
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3296
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gcaaacgcca ucacaaccau ccucacagca gucacuuucu gcuucgcauc cggacaaaac      180

aucacagaag aguucuauca auccacgugc uccgcaguuu ccaaaggaua ccuuggagcc      240

uuacgaaccg gcugguacac cuccgucauc accauagaac ucagcaacau caaagaaauc      300

aaaugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaccucca acuacucaug caaucaaccc ccgcaaccgg cuccggcucc      420

gccaucugcu ccggaguagc cguaugcaaa guccuccacc ucgaaggcga aguuaacaag      480

aucaaguccg cacuccuauc aaccaacaaa gcagucgucu cccuauccaa cggcgucucc      540

guauuaacau ucaaaguccu cgaccucaaa aacuacauag acaaacagcu acuccccauc      600

cuaaacaaac aauccugcuc cauccccaac aucgaaacug ucaucgaguu ccaacagaaa      660

aacaaccgcc uccuagaaau cacccgagag uucuccguaa acgccggcgu cacuaccccc      720

gucucuaccu auaugcuaac caacucugaa cuccuauccc uaaucaacga uaugcccaua      780

acuaacgacc aaaagaaacu uauguccaac aacguacaaa uaguccggca acaaucauac      840

ucuaucaugu gcaucaucaa agaagaagua cuugccuacg uuguccaacu cccacuauac      900

ggcgucauag acacuccaug cuggaaacuu cacaccucac cccucugcac cacuaacacu      960

aaagaaggcu cuaacaucug ccuuacccgc accgaccgcg gaugguacug cgacaacgca     1020

ggcucaguua gcuucuuccc acaagccgaa accugcaaag uccagucaaa ccgugucuuc     1080

ugcgauacca ugaacucgcu cacccucccu uccgaaguca accucugcaa cgucgacauc     1140

uucaacccca aauacgacug caaaaucaug accucaaaaa ccgacguauc uucuuccguc     1200

aucaccuccc ucggcgccau cguauccugc uacggcaaaa ccaaaugcac ugcaucaaac     1260

aaaaaccgag gcaucaucaa aaccuucucg aacggaugcg acuacguauc caacaagggc     1320

gucgacacag ucuccguugg uaacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cuauacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagugac     1440

gaauuugacg ccuccaucuc ccaagucaac gaaaagauca accaaucccu ugccuucaua     1500

cgcaaauccg acgaacuccu acacaacguu aacgccggaa aaucaacaac caacaucaug     1560

aucacaacca ucauaaucgu cauaaucguc auacuccucu cccucauagc cgucggccug     1620

cuauuguacu guaaagcccg cuccacacca gucacacuuu caaaagacca acucuccggg     1680

aucaacaaca ucgccuucuc caacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3297
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3297
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3298
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3298
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3299
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3299
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3300
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3300
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg aucaauaaca uugcauucag caauugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3301
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3301
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3302
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3302
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga aucaauaaca ucgcuuucag caauugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3303
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3303
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacuaaaa gccaaugcca uaaccacuau ucuaacagca      120

guaacauucu guuucgccuc aggacaaaac auaacagaag aauuuuauca auccaccugu      180

uccgcagucu cgaaaggcua ccuuggcgca cuaagaaccg gaugguauac aucaguaaua      240

accauugaac uaucaaauau caaagaaaua aaaugcaacg gaacugacgc aaaagucaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgccguua cagacuuaca acuacuaaug      360

caaucaacuc cagcaacagg aucaggaucu gcuauaugcu caggugucgc cguauguaaa      420

guguuacacc ucgaaggcga aguaaacaaa auaaaaucag cacuacuauc cacaaauaaa      480

gcaguaguau cacuauccaa ugguguauca guacucacau ucaaaguacu agacuuaaaa      540

aauuauauag auaaacaauu acuaccaaua uuaaacaaac aaucaugcuc aauaccaaac      600

auagaaaccg ucauugaauu ucaacaaaaa aacaaucgac uucuugaaau aacacgagaa      660

uuuucaguaa augccggagu aacaacccca gucucaacau acauguuaac caacucugaa      720

cuccuaagcc uaaucaacga caugcccaua acuaacgacc aaaaaaaacu aauguccaau      780

aauguccaaa uaguaagaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cucgccuaug uaguacaacu acccuuauac ggaguaauug acacaccaug uuggaaacua      900

cauacaucac cacuaugcac cacuaacaca aaagaaggcu ccaacauaug ccuaacccga      960

acagaucgcg gaugguauug cgacaacgca ggaaguguau ccuucuuucc acaagcagaa     1020

acaugcaaag uacaauccaa cagaguauuc ugugacacca ugaacucucu aacacuaccu     1080

uccgaaguaa auuuaugcaa cguagacaua uuuaauccca aauacgacug uaaaauaaug     1140

accucaaaaa cugaugucuc aucaucaguc auuacaucac ucggagcaau agucaguugc     1200

uauggaaaaa ccaaaugcac agcuaguaac aaaaacaggg guauaauaaa aacauuuuca     1260

aacggaugcg auuacguauc aaauaaagga guagacaccg uauccguagg aaauacucuc     1320

uacugcguaa acaaacaaga aggacaaucc cuauacguaa aaggcgaacc aaucauuaac     1380

uuuuacgacc cacuuguauu uccaucagac gaauuugaug ccucaauauc ccaagucaau     1440

gaaaaaauaa accaaagucu agcauucauc cgaaaaucag augaacuuuu acacaacgua     1500

aacgccggaa aaucaacaac aaacaucaug aucacaacaa ucaucauagu aauaauaguu     1560

auacuacuuu ccuuaauagc agucggccua cuacucuacu gcaaagcacg auccacacca     1620

guaaccuuau cuaaagacca acucucaggc auaaacaaca uagcauucuc aaacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3304
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3304
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gcaaacgcca ucacaaccau ccucacagca      120

gucacuuucu gcuucgcauc cggacaaaac aucacagaag aguucuauca auccacgugc      180

uccgcaguuu ccaaaggaua ccuuggagcc uuacgaaccg gcugguacac cuccgucauc      240

accauagaac ucagcaacau caaagaaauc aaaugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aacgcaguca ccgaccucca acuacucaug      360

caaucaaccc ccgcaaccgg cuccggcucc gccaucugcu ccggaguagc cguaugcaaa      420

guccuccacc ucgaaggcga aguuaacaag aucaaguccg cacuccuauc aaccaacaaa      480

gcagucgucu cccuauccaa cggcgucucc guauuaacau ucaaaguccu cgaccucaaa      540

aacuacauag acaaacagcu acuccccauc cuaaacaaac aauccugcuc cauccccaac      600

aucgaaacug ucaucgaguu ccaacagaaa aacaaccgcc uccuagaaau cacccgagag      660

uucuccguaa acgccggcgu cacuaccccc gucucuaccu auaugcuaac caacucugaa      720

cuccuauccc uaaucaacga uaugcccaua acuaacgacc aaaagaaacu uauguccaac      780

aacguacaaa uaguccggca acaaucauac ucuaucaugu gcaucaucaa agaagaagua      840

cuugccuacg uuguccaacu cccacuauac ggcgucauag acacuccaug cuggaaacuu      900

cacaccucac cccucugcac cacuaacacu aaagaaggcu cuaacaucug ccuuacccgc      960

accgaccgcg gaugguacug cgacaacgca ggcucaguua gcuucuuccc acaagccgaa     1020

accugcaaag uccagucaaa ccgugucuuc ugcgauacca ugaacucgcu cacccucccu     1080

uccgaaguca accucugcaa cgucgacauc uucaacccca aauacgacug caaaaucaug     1140

accucaaaaa ccgacguauc uucuuccguc aucaccuccc ucggcgccau cguauccugc     1200

uacggcaaaa ccaaaugcac ugcaucaaac aaaaaccgag gcaucaucaa aaccuucucg     1260

aacggaugcg acuacguauc caacaagggc gucgacacag ucuccguugg uaacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cuauacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccagugac gaauuugacg ccuccaucuc ccaagucaac     1440

gaaaagauca accaaucccu ugccuucaua cgcaaauccg acgaacuccu acacaacguu     1500

aacgccggaa aaucaacaac caacaucaug aucacaacca ucauaaucgu cauaaucguc     1560

auacuccucu cccucauagc cgucggccug cuauuguacu guaaagcccg cuccacacca     1620

gucacacuuu caaaagacca acucuccggg aucaacaaca ucgccuucuc caacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3305
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3305
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3306
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3306
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3307
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3307
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3308
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3308
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggaucaau aacauugcau ucagcaauug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3309
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3309
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3310
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3310
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaaucaau aacaucgcuu ucagcaauug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3311
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3311
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu aaaagccaau gccauaacca cuauucuaac agcaguaaca      180

uucuguuucg ccucaggaca aaacauaaca gaagaauuuu aucaauccac cuguuccgca      240

gucucgaaag gcuaccuugg cgcacuaaga accggauggu auacaucagu aauaaccauu      300

gaacuaucaa auaucaaaga aauaaaaugc aacggaacug acgcaaaagu caaacuaaua      360

aaacaagaau uagacaaaua caaaaacgcc guuacagacu uacaacuacu aaugcaauca      420

acuccagcaa caggaucagg aucugcuaua ugcucaggug ucgccguaug uaaaguguua      480

caccucgaag gcgaaguaaa caaaauaaaa ucagcacuac uauccacaaa uaaagcagua      540

guaucacuau ccaauggugu aucaguacuc acauucaaag uacuagacuu aaaaaauuau      600

auagauaaac aauuacuacc aauauuaaac aaacaaucau gcucaauacc aaacauagaa      660

accgucauug aauuucaaca aaaaaacaau cgacuucuug aaauaacacg agaauuuuca      720

guaaaugccg gaguaacaac cccagucuca acauacaugu uaaccaacuc ugaacuccua      780

agccuaauca acgacaugcc cauaacuaac gaccaaaaaa aacuaauguc caauaauguc      840

caaauaguaa gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccucgcc      900

uauguaguac aacuacccuu auacggagua auugacacac cauguuggaa acuacauaca      960

ucaccacuau gcaccacuaa cacaaaagaa ggcuccaaca uaugccuaac ccgaacagau     1020

cgcggauggu auugcgacaa cgcaggaagu guauccuucu uuccacaagc agaaacaugc     1080

aaaguacaau ccaacagagu auucugugac accaugaacu cucuaacacu accuuccgaa     1140

guaaauuuau gcaacguaga cauauuuaau cccaaauacg acuguaaaau aaugaccuca     1200

aaaacugaug ucucaucauc agucauuaca ucacucggag caauagucag uugcuaugga     1260

aaaaccaaau gcacagcuag uaacaaaaac agggguauaa uaaaaacauu uucaaacgga     1320

ugcgauuacg uaucaaauaa aggaguagac accguauccg uaggaaauac ucucuacugc     1380

guaaacaaac aagaaggaca aucccuauac guaaaaggcg aaccaaucau uaacuuuuac     1440

gacccacuug uauuuccauc agacgaauuu gaugccucaa uaucccaagu caaugaaaaa     1500

auaaaccaaa gucuagcauu cauccgaaaa ucagaugaac uuuuacacaa cguaaacgcc     1560

ggaaaaucaa caacaaacau caugaucaca acaaucauca uaguaauaau aguuauacua     1620

cuuuccuuaa uagcagucgg ccuacuacuc uacugcaaag cacgauccac accaguaacc     1680

uuaucuaaag accaacucuc aggcauaaac aacauagcau ucucaaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3312
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3312
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagcaaac gccaucacaa ccauccucac agcagucacu      180

uucugcuucg cauccggaca aaacaucaca gaagaguucu aucaauccac gugcuccgca      240

guuuccaaag gauaccuugg agccuuacga accggcuggu acaccuccgu caucaccaua      300

gaacucagca acaucaaaga aaucaaaugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaacgca gucaccgacc uccaacuacu caugcaauca      420

acccccgcaa ccggcuccgg cuccgccauc ugcuccggag uagccguaug caaaguccuc      480

caccucgaag gcgaaguuaa caagaucaag uccgcacucc uaucaaccaa caaagcaguc      540

gucucccuau ccaacggcgu cuccguauua acauucaaag uccucgaccu caaaaacuac      600

auagacaaac agcuacuccc cauccuaaac aaacaauccu gcuccauccc caacaucgaa      660

acugucaucg aguuccaaca gaaaaacaac cgccuccuag aaaucacccg agaguucucc      720

guaaacgccg gcgucacuac ccccgucucu accuauaugc uaaccaacuc ugaacuccua      780

ucccuaauca acgauaugcc cauaacuaac gaccaaaaga aacuuauguc caacaacgua      840

caaauagucc ggcaacaauc auacucuauc augugcauca ucaaagaaga aguacuugcc      900

uacguugucc aacucccacu auacggcguc auagacacuc caugcuggaa acuucacacc      960

ucaccccucu gcaccacuaa cacuaaagaa ggcucuaaca ucugccuuac ccgcaccgac     1020

cgcggauggu acugcgacaa cgcaggcuca guuagcuucu ucccacaagc cgaaaccugc     1080

aaaguccagu caaaccgugu cuucugcgau accaugaacu cgcucacccu cccuuccgaa     1140

gucaaccucu gcaacgucga caucuucaac cccaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg uaucuucuuc cgucaucacc ucccucggcg ccaucguauc cugcuacggc     1260

aaaaccaaau gcacugcauc aaacaaaaac cgaggcauca ucaaaaccuu cucgaacgga     1320

ugcgacuacg uauccaacaa gggcgucgac acagucuccg uugguaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccuauac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccag ugacgaauuu gacgccucca ucucccaagu caacgaaaag     1500

aucaaccaau cccuugccuu cauacgcaaa uccgacgaac uccuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaacau caugaucaca accaucauaa ucgucauaau cgucauacuc     1620

cucucccuca uagccgucgg ccugcuauug uacuguaaag cccgcuccac accagucaca     1680

cuuucaaaag accaacucuc cgggaucaac aacaucgccu ucuccaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3313
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3313
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3314
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3314
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3315
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3315
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3316
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3316
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gaucaauaac     1680

auugcauuca gcaauugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3317
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3317
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3318
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3318
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aaucaauaac     1680

aucgcuuuca gcaauugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3319
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3319
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacuaaa agccaaugcc      120

auaaccacua uucuaacagc aguaacauuc uguuucgccu caggacaaaa cauaacagaa      180

gaauuuuauc aauccaccug uuccgcaguc ucgaaaggcu accuuggcgc acuaagaacc      240

ggaugguaua caucaguaau aaccauugaa cuaucaaaua ucaaagaaau aaaaugcaac      300

ggaacugacg caaaagucaa acuaauaaaa caagaauuag acaaauacaa aaacgccguu      360

acagacuuac aacuacuaau gcaaucaacu ccagcaacag gaucaggauc ugcuauaugc      420

ucaggugucg ccguauguaa aguguuacac cucgaaggcg aaguaaacaa aauaaaauca      480

gcacuacuau ccacaaauaa agcaguagua ucacuaucca augguguauc aguacucaca      540

uucaaaguac uagacuuaaa aaauuauaua gauaaacaau uacuaccaau auuaaacaaa      600

caaucaugcu caauaccaaa cauagaaacc gucauugaau uucaacaaaa aaacaaucga      660

cuucuugaaa uaacacgaga auuuucagua aaugccggag uaacaacccc agucucaaca      720

uacauguuaa ccaacucuga acuccuaagc cuaaucaacg acaugcccau aacuaacgac      780

caaaaaaaac uaauguccaa uaauguccaa auaguaagac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccucgccuau guaguacaac uacccuuaua cggaguaauu      900

gacacaccau guuggaaacu acauacauca ccacuaugca ccacuaacac aaaagaaggc      960

uccaacauau gccuaacccg aacagaucgc ggaugguauu gcgacaacgc aggaagugua     1020

uccuucuuuc cacaagcaga aacaugcaaa guacaaucca acagaguauu cugugacacc     1080

augaacucuc uaacacuacc uuccgaagua aauuuaugca acguagacau auuuaauccc     1140

aaauacgacu guaaaauaau gaccucaaaa acugaugucu caucaucagu cauuacauca     1200

cucggagcaa uagucaguug cuauggaaaa accaaaugca cagcuaguaa caaaaacagg     1260

gguauaauaa aaacauuuuc aaacggaugc gauuacguau caaauaaagg aguagacacc     1320

guauccguag gaaauacucu cuacugcgua aacaaacaag aaggacaauc ccuauacgua     1380

aaaggcgaac caaucauuaa cuuuuacgac ccacuuguau uuccaucaga cgaauuugau     1440

gccucaauau cccaagucaa ugaaaaaaua aaccaaaguc uagcauucau ccgaaaauca     1500

gaugaacuuu uacacaacgu aaacgccgga aaaucaacaa caaacaucau gaucacaaca     1560

aucaucauag uaauaauagu uauacuacuu uccuuaauag cagucggccu acuacucuac     1620

ugcaaagcac gauccacacc aguaaccuua ucuaaagacc aacucucagg cauaaacaac     1680

auagcauucu caaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3320
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3320
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agcaaacgcc      120

aucacaacca uccucacagc agucacuuuc ugcuucgcau ccggacaaaa caucacagaa      180

gaguucuauc aauccacgug cuccgcaguu uccaaaggau accuuggagc cuuacgaacc      240

ggcugguaca ccuccgucau caccauagaa cucagcaaca ucaaagaaau caaaugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaccucc aacuacucau gcaaucaacc cccgcaaccg gcuccggcuc cgccaucugc      420

uccggaguag ccguaugcaa aguccuccac cucgaaggcg aaguuaacaa gaucaagucc      480

gcacuccuau caaccaacaa agcagucguc ucccuaucca acggcgucuc cguauuaaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaaacagc uacuccccau ccuaaacaaa      600

caauccugcu ccauccccaa caucgaaacu gucaucgagu uccaacagaa aaacaaccgc      660

cuccuagaaa ucacccgaga guucuccgua aacgccggcg ucacuacccc cgucucuacc      720

uauaugcuaa ccaacucuga acuccuaucc cuaaucaacg auaugcccau aacuaacgac      780

caaaagaaac uuauguccaa caacguacaa auaguccggc aacaaucaua cucuaucaug      840

ugcaucauca aagaagaagu acuugccuac guuguccaac ucccacuaua cggcgucaua      900

gacacuccau gcuggaaacu ucacaccuca ccccucugca ccacuaacac uaaagaaggc      960

ucuaacaucu gccuuacccg caccgaccgc ggaugguacu gcgacaacgc aggcucaguu     1020

agcuucuucc cacaagccga aaccugcaaa guccagucaa accgugucuu cugcgauacc     1080

augaacucgc ucacccuccc uuccgaaguc aaccucugca acgucgacau cuucaacccc     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacguau cuucuuccgu caucaccucc     1200

cucggcgcca ucguauccug cuacggcaaa accaaaugca cugcaucaaa caaaaaccga     1260

ggcaucauca aaaccuucuc gaacggaugc gacuacguau ccaacaaggg cgucgacaca     1320

gucuccguug guaacacccu cuacugcguc aacaaacaag aaggccaauc ccuauacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccaguga cgaauuugac     1440

gccuccaucu cccaagucaa cgaaaagauc aaccaauccc uugccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu uaacgccgga aaaucaacaa ccaacaucau gaucacaacc     1560

aucauaaucg ucauaaucgu cauacuccuc ucccucauag ccgucggccu gcuauuguac     1620

uguaaagccc gcuccacacc agucacacuu ucaaaagacc aacucuccgg gaucaacaac     1680

aucgccuucu ccaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3321
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3321
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3322
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3322
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3323
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3323
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3324
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3324
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gaucaauaac     1680

auugcauuca gcaauugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3325
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3325
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3326
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3326
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aaucaauaac     1680

aucgcuuuca gcaauugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3327
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3327
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacuaaa agccaaugcc      120

auaaccacua uucuaacagc aguaacauuc uguuucgccu caggacaaaa cauaacagaa      180

gaauuuuauc aauccaccug uuccgcaguc ucgaaaggcu accuuggcgc acuaagaacc      240

ggaugguaua caucaguaau aaccauugaa cuaucaaaua ucaaagaaau aaaaugcaac      300

ggaacugacg caaaagucaa acuaauaaaa caagaauuag acaaauacaa aaacgccguu      360

acagacuuac aacuacuaau gcaaucaacu ccagcaacag gaucaggauc ugcuauaugc      420

ucaggugucg ccguauguaa aguguuacac cucgaaggcg aaguaaacaa aauaaaauca      480

gcacuacuau ccacaaauaa agcaguagua ucacuaucca augguguauc aguacucaca      540

uucaaaguac uagacuuaaa aaauuauaua gauaaacaau uacuaccaau auuaaacaaa      600

caaucaugcu caauaccaaa cauagaaacc gucauugaau uucaacaaaa aaacaaucga      660

cuucuugaaa uaacacgaga auuuucagua aaugccggag uaacaacccc agucucaaca      720

uacauguuaa ccaacucuga acuccuaagc cuaaucaacg acaugcccau aacuaacgac      780

caaaaaaaac uaauguccaa uaauguccaa auaguaagac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccucgccuau guaguacaac uacccuuaua cggaguaauu      900

gacacaccau guuggaaacu acauacauca ccacuaugca ccacuaacac aaaagaaggc      960

uccaacauau gccuaacccg aacagaucgc ggaugguauu gcgacaacgc aggaagugua     1020

uccuucuuuc cacaagcaga aacaugcaaa guacaaucca acagaguauu cugugacacc     1080

augaacucuc uaacacuacc uuccgaagua aauuuaugca acguagacau auuuaauccc     1140

aaauacgacu guaaaauaau gaccucaaaa acugaugucu caucaucagu cauuacauca     1200

cucggagcaa uagucaguug cuauggaaaa accaaaugca cagcuaguaa caaaaacagg     1260

gguauaauaa aaacauuuuc aaacggaugc gauuacguau caaauaaagg aguagacacc     1320

guauccguag gaaauacucu cuacugcgua aacaaacaag aaggacaauc ccuauacgua     1380

aaaggcgaac caaucauuaa cuuuuacgac ccacuuguau uuccaucaga cgaauuugau     1440

gccucaauau cccaagucaa ugaaaaaaua aaccaaaguc uagcauucau ccgaaaauca     1500

gaugaacuuu uacacaacgu aaacgccgga aaaucaacaa caaacaucau gaucacaaca     1560

aucaucauag uaauaauagu uauacuacuu uccuuaauag cagucggccu acuacucuac     1620

ugcaaagcac gauccacacc aguaaccuua ucuaaagacc aacucucagg cauaaacaac     1680

auagcauucu caaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3328
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3328
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agcaaacgcc      120

aucacaacca uccucacagc agucacuuuc ugcuucgcau ccggacaaaa caucacagaa      180

gaguucuauc aauccacgug cuccgcaguu uccaaaggau accuuggagc cuuacgaacc      240

ggcugguaca ccuccgucau caccauagaa cucagcaaca ucaaagaaau caaaugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaccucc aacuacucau gcaaucaacc cccgcaaccg gcuccggcuc cgccaucugc      420

uccggaguag ccguaugcaa aguccuccac cucgaaggcg aaguuaacaa gaucaagucc      480

gcacuccuau caaccaacaa agcagucguc ucccuaucca acggcgucuc cguauuaaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaaacagc uacuccccau ccuaaacaaa      600

caauccugcu ccauccccaa caucgaaacu gucaucgagu uccaacagaa aaacaaccgc      660

cuccuagaaa ucacccgaga guucuccgua aacgccggcg ucacuacccc cgucucuacc      720

uauaugcuaa ccaacucuga acuccuaucc cuaaucaacg auaugcccau aacuaacgac      780

caaaagaaac uuauguccaa caacguacaa auaguccggc aacaaucaua cucuaucaug      840

ugcaucauca aagaagaagu acuugccuac guuguccaac ucccacuaua cggcgucaua      900

gacacuccau gcuggaaacu ucacaccuca ccccucugca ccacuaacac uaaagaaggc      960

ucuaacaucu gccuuacccg caccgaccgc ggaugguacu gcgacaacgc aggcucaguu     1020

agcuucuucc cacaagccga aaccugcaaa guccagucaa accgugucuu cugcgauacc     1080

augaacucgc ucacccuccc uuccgaaguc aaccucugca acgucgacau cuucaacccc     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacguau cuucuuccgu caucaccucc     1200

cucggcgcca ucguauccug cuacggcaaa accaaaugca cugcaucaaa caaaaaccga     1260

ggcaucauca aaaccuucuc gaacggaugc gacuacguau ccaacaaggg cgucgacaca     1320

gucuccguug guaacacccu cuacugcguc aacaaacaag aaggccaauc ccuauacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccaguga cgaauuugac     1440

gccuccaucu cccaagucaa cgaaaagauc aaccaauccc uugccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu uaacgccgga aaaucaacaa ccaacaucau gaucacaacc     1560

aucauaaucg ucauaaucgu cauacuccuc ucccucauag ccgucggccu gcuauuguac     1620

uguaaagccc gcuccacacc agucacacuu ucaaaagacc aacucuccgg gaucaacaac     1680

aucgccuucu ccaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  3329
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3329
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3330
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3330
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3331
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3331
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3332
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3332
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gaucaauaac     1680

auugcauuca gcaauugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3333
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3333
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3334
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3334
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aaucaauaac     1680

aucgcuuuca gcaauugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3335
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3335
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacuaaa agccaaugcc      120

auaaccacua uucuaacagc aguaacauuc uguuucgccu caggacaaaa cauaacagaa      180

gaauuuuauc aauccaccug uuccgcaguc ucgaaaggcu accuuggcgc acuaagaacc      240

ggaugguaua caucaguaau aaccauugaa cuaucaaaua ucaaagaaau aaaaugcaac      300

ggaacugacg caaaagucaa acuaauaaaa caagaauuag acaaauacaa aaacgccguu      360

acagacuuac aacuacuaau gcaaucaacu ccagcaacag gaucaggauc ugcuauaugc      420

ucaggugucg ccguauguaa aguguuacac cucgaaggcg aaguaaacaa aauaaaauca      480

gcacuacuau ccacaaauaa agcaguagua ucacuaucca augguguauc aguacucaca      540

uucaaaguac uagacuuaaa aaauuauaua gauaaacaau uacuaccaau auuaaacaaa      600

caaucaugcu caauaccaaa cauagaaacc gucauugaau uucaacaaaa aaacaaucga      660

cuucuugaaa uaacacgaga auuuucagua aaugccggag uaacaacccc agucucaaca      720

uacauguuaa ccaacucuga acuccuaagc cuaaucaacg acaugcccau aacuaacgac      780

caaaaaaaac uaauguccaa uaauguccaa auaguaagac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccucgccuau guaguacaac uacccuuaua cggaguaauu      900

gacacaccau guuggaaacu acauacauca ccacuaugca ccacuaacac aaaagaaggc      960

uccaacauau gccuaacccg aacagaucgc ggaugguauu gcgacaacgc aggaagugua     1020

uccuucuuuc cacaagcaga aacaugcaaa guacaaucca acagaguauu cugugacacc     1080

augaacucuc uaacacuacc uuccgaagua aauuuaugca acguagacau auuuaauccc     1140

aaauacgacu guaaaauaau gaccucaaaa acugaugucu caucaucagu cauuacauca     1200

cucggagcaa uagucaguug cuauggaaaa accaaaugca cagcuaguaa caaaaacagg     1260

gguauaauaa aaacauuuuc aaacggaugc gauuacguau caaauaaagg aguagacacc     1320

guauccguag gaaauacucu cuacugcgua aacaaacaag aaggacaauc ccuauacgua     1380

aaaggcgaac caaucauuaa cuuuuacgac ccacuuguau uuccaucaga cgaauuugau     1440

gccucaauau cccaagucaa ugaaaaaaua aaccaaaguc uagcauucau ccgaaaauca     1500

gaugaacuuu uacacaacgu aaacgccgga aaaucaacaa caaacaucau gaucacaaca     1560

aucaucauag uaauaauagu uauacuacuu uccuuaauag cagucggccu acuacucuac     1620

ugcaaagcac gauccacacc aguaaccuua ucuaaagacc aacucucagg cauaaacaac     1680

auagcauucu caaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3336
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3336
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agcaaacgcc      120

aucacaacca uccucacagc agucacuuuc ugcuucgcau ccggacaaaa caucacagaa      180

gaguucuauc aauccacgug cuccgcaguu uccaaaggau accuuggagc cuuacgaacc      240

ggcugguaca ccuccgucau caccauagaa cucagcaaca ucaaagaaau caaaugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaccucc aacuacucau gcaaucaacc cccgcaaccg gcuccggcuc cgccaucugc      420

uccggaguag ccguaugcaa aguccuccac cucgaaggcg aaguuaacaa gaucaagucc      480

gcacuccuau caaccaacaa agcagucguc ucccuaucca acggcgucuc cguauuaaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaaacagc uacuccccau ccuaaacaaa      600

caauccugcu ccauccccaa caucgaaacu gucaucgagu uccaacagaa aaacaaccgc      660

cuccuagaaa ucacccgaga guucuccgua aacgccggcg ucacuacccc cgucucuacc      720

uauaugcuaa ccaacucuga acuccuaucc cuaaucaacg auaugcccau aacuaacgac      780

caaaagaaac uuauguccaa caacguacaa auaguccggc aacaaucaua cucuaucaug      840

ugcaucauca aagaagaagu acuugccuac guuguccaac ucccacuaua cggcgucaua      900

gacacuccau gcuggaaacu ucacaccuca ccccucugca ccacuaacac uaaagaaggc      960

ucuaacaucu gccuuacccg caccgaccgc ggaugguacu gcgacaacgc aggcucaguu     1020

agcuucuucc cacaagccga aaccugcaaa guccagucaa accgugucuu cugcgauacc     1080

augaacucgc ucacccuccc uuccgaaguc aaccucugca acgucgacau cuucaacccc     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacguau cuucuuccgu caucaccucc     1200

cucggcgcca ucguauccug cuacggcaaa accaaaugca cugcaucaaa caaaaaccga     1260

ggcaucauca aaaccuucuc gaacggaugc gacuacguau ccaacaaggg cgucgacaca     1320

gucuccguug guaacacccu cuacugcguc aacaaacaag aaggccaauc ccuauacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccaguga cgaauuugac     1440

gccuccaucu cccaagucaa cgaaaagauc aaccaauccc uugccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu uaacgccgga aaaucaacaa ccaacaucau gaucacaacc     1560

aucauaaucg ucauaaucgu cauacuccuc ucccucauag ccgucggccu gcuauuguac     1620

uguaaagccc gcuccacacc agucacacuu ucaaaagacc aacucuccgg gaucaacaac     1680

aucgccuucu ccaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  3337
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3337
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3338
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3338
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3339
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3339
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3340
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3340
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcucaacacc cgugacccug aguaaagauc aacucucugg gaucaauaac     1680

auugcauuca gcaauugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3341
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3341
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3342
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3342
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaagcacacc cgugacccuu ucuaaagauc aacucuccgg aaucaauaac     1680

aucgcuuuca gcaauugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3343
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3343
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacuaaa agccaaugcc      120

auaaccacua uucuaacagc aguaacauuc uguuucgccu caggacaaaa cauaacagaa      180

gaauuuuauc aauccaccug uuccgcaguc ucgaaaggcu accuuggcgc acuaagaacc      240

ggaugguaua caucaguaau aaccauugaa cuaucaaaua ucaaagaaau aaaaugcaac      300

ggaacugacg caaaagucaa acuaauaaaa caagaauuag acaaauacaa aaacgccguu      360

acagacuuac aacuacuaau gcaaucaacu ccagcaacag gaucaggauc ugcuauaugc      420

ucaggugucg ccguauguaa aguguuacac cucgaaggcg aaguaaacaa aauaaaauca      480

gcacuacuau ccacaaauaa agcaguagua ucacuaucca augguguauc aguacucaca      540

uucaaaguac uagacuuaaa aaauuauaua gauaaacaau uacuaccaau auuaaacaaa      600

caaucaugcu caauaccaaa cauagaaacc gucauugaau uucaacaaaa aaacaaucga      660

cuucuugaaa uaacacgaga auuuucagua aaugccggag uaacaacccc agucucaaca      720

uacauguuaa ccaacucuga acuccuaagc cuaaucaacg acaugcccau aacuaacgac      780

caaaaaaaac uaauguccaa uaauguccaa auaguaagac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccucgccuau guaguacaac uacccuuaua cggaguaauu      900

gacacaccau guuggaaacu acauacauca ccacuaugca ccacuaacac aaaagaaggc      960

uccaacauau gccuaacccg aacagaucgc ggaugguauu gcgacaacgc aggaagugua     1020

uccuucuuuc cacaagcaga aacaugcaaa guacaaucca acagaguauu cugugacacc     1080

augaacucuc uaacacuacc uuccgaagua aauuuaugca acguagacau auuuaauccc     1140

aaauacgacu guaaaauaau gaccucaaaa acugaugucu caucaucagu cauuacauca     1200

cucggagcaa uagucaguug cuauggaaaa accaaaugca cagcuaguaa caaaaacagg     1260

gguauaauaa aaacauuuuc aaacggaugc gauuacguau caaauaaagg aguagacacc     1320

guauccguag gaaauacucu cuacugcgua aacaaacaag aaggacaauc ccuauacgua     1380

aaaggcgaac caaucauuaa cuuuuacgac ccacuuguau uuccaucaga cgaauuugau     1440

gccucaauau cccaagucaa ugaaaaaaua aaccaaaguc uagcauucau ccgaaaauca     1500

gaugaacuuu uacacaacgu aaacgccgga aaaucaacaa caaacaucau gaucacaaca     1560

aucaucauag uaauaauagu uauacuacuu uccuuaauag cagucggccu acuacucuac     1620

ugcaaagcac gauccacacc aguaaccuua ucuaaagacc aacucucagg cauaaacaac     1680

auagcauucu caaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3344
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3344
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agcaaacgcc      120

aucacaacca uccucacagc agucacuuuc ugcuucgcau ccggacaaaa caucacagaa      180

gaguucuauc aauccacgug cuccgcaguu uccaaaggau accuuggagc cuuacgaacc      240

ggcugguaca ccuccgucau caccauagaa cucagcaaca ucaaagaaau caaaugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaccucc aacuacucau gcaaucaacc cccgcaaccg gcuccggcuc cgccaucugc      420

uccggaguag ccguaugcaa aguccuccac cucgaaggcg aaguuaacaa gaucaagucc      480

gcacuccuau caaccaacaa agcagucguc ucccuaucca acggcgucuc cguauuaaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaaacagc uacuccccau ccuaaacaaa      600

caauccugcu ccauccccaa caucgaaacu gucaucgagu uccaacagaa aaacaaccgc      660

cuccuagaaa ucacccgaga guucuccgua aacgccggcg ucacuacccc cgucucuacc      720

uauaugcuaa ccaacucuga acuccuaucc cuaaucaacg auaugcccau aacuaacgac      780

caaaagaaac uuauguccaa caacguacaa auaguccggc aacaaucaua cucuaucaug      840

ugcaucauca aagaagaagu acuugccuac guuguccaac ucccacuaua cggcgucaua      900

gacacuccau gcuggaaacu ucacaccuca ccccucugca ccacuaacac uaaagaaggc      960

ucuaacaucu gccuuacccg caccgaccgc ggaugguacu gcgacaacgc aggcucaguu     1020

agcuucuucc cacaagccga aaccugcaaa guccagucaa accgugucuu cugcgauacc     1080

augaacucgc ucacccuccc uuccgaaguc aaccucugca acgucgacau cuucaacccc     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacguau cuucuuccgu caucaccucc     1200

cucggcgcca ucguauccug cuacggcaaa accaaaugca cugcaucaaa caaaaaccga     1260

ggcaucauca aaaccuucuc gaacggaugc gacuacguau ccaacaaggg cgucgacaca     1320

gucuccguug guaacacccu cuacugcguc aacaaacaag aaggccaauc ccuauacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccaguga cgaauuugac     1440

gccuccaucu cccaagucaa cgaaaagauc aaccaauccc uugccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu uaacgccgga aaaucaacaa ccaacaucau gaucacaacc     1560

aucauaaucg ucauaaucgu cauacuccuc ucccucauag ccgucggccu gcuauuguac     1620

uguaaagccc gcuccacacc agucacacuu ucaaaagacc aacucuccgg gaucaacaac     1680

aucgccuucu ccaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  3345
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3345
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3346
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3346
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3347
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3347
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3348
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3348
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau caauaacauu gcauucagca     1680

auugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3349
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3349
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3350
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3350
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau caauaacauc gcuuucagca     1680

auugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3351
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3351
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacuaaaagc caaugccaua accacuauuc      120

uaacagcagu aacauucugu uucgccucag gacaaaacau aacagaagaa uuuuaucaau      180

ccaccuguuc cgcagucucg aaaggcuacc uuggcgcacu aagaaccgga ugguauacau      240

caguaauaac cauugaacua ucaaauauca aagaaauaaa augcaacgga acugacgcaa      300

aagucaaacu aauaaaacaa gaauuagaca aauacaaaaa cgccguuaca gacuuacaac      360

uacuaaugca aucaacucca gcaacaggau caggaucugc uauaugcuca ggugucgccg      420

uauguaaagu guuacaccuc gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca      480

caaauaaagc aguaguauca cuauccaaug guguaucagu acucacauuc aaaguacuag      540

acuuaaaaaa uuauauagau aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa      600

uaccaaacau agaaaccguc auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa      660

cacgagaauu uucaguaaau gccggaguaa caaccccagu cucaacauac auguuaacca      720

acucugaacu ccuaagccua aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa      780

uguccaauaa uguccaaaua guaagacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu cgccuaugua guacaacuac ccuuauacgg aguaauugac acaccauguu      900

ggaaacuaca uacaucacca cuaugcacca cuaacacaaa agaaggcucc aacauaugcc      960

uaacccgaac agaucgcgga ugguauugcg acaacgcagg aaguguaucc uucuuuccac     1020

aagcagaaac augcaaagua caauccaaca gaguauucug ugacaccaug aacucucuaa     1080

cacuaccuuc cgaaguaaau uuaugcaacg uagacauauu uaaucccaaa uacgacugua     1140

aaauaaugac cucaaaaacu gaugucucau caucagucau uacaucacuc ggagcaauag     1200

ucaguugcua uggaaaaacc aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa     1260

cauuuucaaa cggaugcgau uacguaucaa auaaaggagu agacaccgua uccguaggaa     1320

auacucucua cugcguaaac aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa     1380

ucauuaacuu uuacgaccca cuuguauuuc caucagacga auuugaugcc ucaauauccc     1440

aagucaauga aaaaauaaac caaagucuag cauucauccg aaaaucagau gaacuuuuac     1500

acaacguaaa cgccggaaaa ucaacaacaa acaucaugau cacaacaauc aucauaguaa     1560

uaauaguuau acuacuuucc uuaauagcag ucggccuacu acucuacugc aaagcacgau     1620

ccacaccagu aaccuuaucu aaagaccaac ucucaggcau aaacaacaua gcauucucaa     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3352
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3352
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc aaacgccauc acaaccaucc      120

ucacagcagu cacuuucugc uucgcauccg gacaaaacau cacagaagag uucuaucaau      180

ccacgugcuc cgcaguuucc aaaggauacc uuggagccuu acgaaccggc ugguacaccu      240

ccgucaucac cauagaacuc agcaacauca aagaaaucaa augcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa cgcagucacc gaccuccaac      360

uacucaugca aucaaccccc gcaaccggcu ccggcuccgc caucugcucc ggaguagccg      420

uaugcaaagu ccuccaccuc gaaggcgaag uuaacaagau caaguccgca cuccuaucaa      480

ccaacaaagc agucgucucc cuauccaacg gcgucuccgu auuaacauuc aaaguccucg      540

accucaaaaa cuacauagac aaacagcuac uccccauccu aaacaaacaa uccugcucca      600

uccccaacau cgaaacuguc aucgaguucc aacagaaaaa caaccgccuc cuagaaauca      660

cccgagaguu cuccguaaac gccggcguca cuacccccgu cucuaccuau augcuaacca      720

acucugaacu ccuaucccua aucaacgaua ugcccauaac uaacgaccaa aagaaacuua      780

uguccaacaa cguacaaaua guccggcaac aaucauacuc uaucaugugc aucaucaaag      840

aagaaguacu ugccuacguu guccaacucc cacuauacgg cgucauagac acuccaugcu      900

ggaaacuuca caccucaccc cucugcacca cuaacacuaa agaaggcucu aacaucugcc      960

uuacccgcac cgaccgcgga ugguacugcg acaacgcagg cucaguuagc uucuucccac     1020

aagccgaaac cugcaaaguc cagucaaacc gugucuucug cgauaccaug aacucgcuca     1080

cccucccuuc cgaagucaac cucugcaacg ucgacaucuu caaccccaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacguaucuu cuuccgucau caccucccuc ggcgccaucg     1200

uauccugcua cggcaaaacc aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa     1260

ccuucucgaa cggaugcgac uacguaucca acaagggcgu cgacacaguc uccguuggua     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu auacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccagugacga auuugacgcc uccaucuccc     1440

aagucaacga aaagaucaac caaucccuug ccuucauacg caaauccgac gaacuccuac     1500

acaacguuaa cgccggaaaa ucaacaacca acaucaugau cacaaccauc auaaucguca     1560

uaaucgucau acuccucucc cucauagccg ucggccugcu auuguacugu aaagcccgcu     1620

ccacaccagu cacacuuuca aaagaccaac ucuccgggau caacaacauc gccuucucca     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  3353
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3353
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3354
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3354
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

ccacccccgu gacccugagc aaggaccagc ucuccggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3355
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3355
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3356
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3356
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

caacacccgu gacccugagu aaagaucaac ucucugggau caauaacauu gcauucagca     1680

auugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3357
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3357
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3358
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3358
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagaa     1620

gcacacccgu gacccuuucu aaagaucaac ucuccggaau caauaacauc gcuuucagca     1680

auugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3359
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3359
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacuaaaagc caaugccaua accacuauuc      120

uaacagcagu aacauucugu uucgccucag gacaaaacau aacagaagaa uuuuaucaau      180

ccaccuguuc cgcagucucg aaaggcuacc uuggcgcacu aagaaccgga ugguauacau      240

caguaauaac cauugaacua ucaaauauca aagaaauaaa augcaacgga acugacgcaa      300

aagucaaacu aauaaaacaa gaauuagaca aauacaaaaa cgccguuaca gacuuacaac      360

uacuaaugca aucaacucca gcaacaggau caggaucugc uauaugcuca ggugucgccg      420

uauguaaagu guuacaccuc gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca      480

caaauaaagc aguaguauca cuauccaaug guguaucagu acucacauuc aaaguacuag      540

acuuaaaaaa uuauauagau aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa      600

uaccaaacau agaaaccguc auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa      660

cacgagaauu uucaguaaau gccggaguaa caaccccagu cucaacauac auguuaacca      720

acucugaacu ccuaagccua aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa      780

uguccaauaa uguccaaaua guaagacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu cgccuaugua guacaacuac ccuuauacgg aguaauugac acaccauguu      900

ggaaacuaca uacaucacca cuaugcacca cuaacacaaa agaaggcucc aacauaugcc      960

uaacccgaac agaucgcgga ugguauugcg acaacgcagg aaguguaucc uucuuuccac     1020

aagcagaaac augcaaagua caauccaaca gaguauucug ugacaccaug aacucucuaa     1080

cacuaccuuc cgaaguaaau uuaugcaacg uagacauauu uaaucccaaa uacgacugua     1140

aaauaaugac cucaaaaacu gaugucucau caucagucau uacaucacuc ggagcaauag     1200

ucaguugcua uggaaaaacc aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa     1260

cauuuucaaa cggaugcgau uacguaucaa auaaaggagu agacaccgua uccguaggaa     1320

auacucucua cugcguaaac aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa     1380

ucauuaacuu uuacgaccca cuuguauuuc caucagacga auuugaugcc ucaauauccc     1440

aagucaauga aaaaauaaac caaagucuag cauucauccg aaaaucagau gaacuuuuac     1500

acaacguaaa cgccggaaaa ucaacaacaa acaucaugau cacaacaauc aucauaguaa     1560

uaauaguuau acuacuuucc uuaauagcag ucggccuacu acucuacugc aaagcacgau     1620

ccacaccagu aaccuuaucu aaagaccaac ucucaggcau aaacaacaua gcauucucaa     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3360
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3360
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc aaacgccauc acaaccaucc      120

ucacagcagu cacuuucugc uucgcauccg gacaaaacau cacagaagag uucuaucaau      180

ccacgugcuc cgcaguuucc aaaggauacc uuggagccuu acgaaccggc ugguacaccu      240

ccgucaucac cauagaacuc agcaacauca aagaaaucaa augcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaaaaa cgcagucacc gaccuccaac      360

uacucaugca aucaaccccc gcaaccggcu ccggcuccgc caucugcucc ggaguagccg      420

uaugcaaagu ccuccaccuc gaaggcgaag uuaacaagau caaguccgca cuccuaucaa      480

ccaacaaagc agucgucucc cuauccaacg gcgucuccgu auuaacauuc aaaguccucg      540

accucaaaaa cuacauagac aaacagcuac uccccauccu aaacaaacaa uccugcucca      600

uccccaacau cgaaacuguc aucgaguucc aacagaaaaa caaccgccuc cuagaaauca      660

cccgagaguu cuccguaaac gccggcguca cuacccccgu cucuaccuau augcuaacca      720

acucugaacu ccuaucccua aucaacgaua ugcccauaac uaacgaccaa aagaaacuua      780

uguccaacaa cguacaaaua guccggcaac aaucauacuc uaucaugugc aucaucaaag      840

aagaaguacu ugccuacguu guccaacucc cacuauacgg cgucauagac acuccaugcu      900

ggaaacuuca caccucaccc cucugcacca cuaacacuaa agaaggcucu aacaucugcc      960

uuacccgcac cgaccgcgga ugguacugcg acaacgcagg cucaguuagc uucuucccac     1020

aagccgaaac cugcaaaguc cagucaaacc gugucuucug cgauaccaug aacucgcuca     1080

cccucccuuc cgaagucaac cucugcaacg ucgacaucuu caaccccaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacguaucuu cuuccgucau caccucccuc ggcgccaucg     1200

uauccugcua cggcaaaacc aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa     1260

ccuucucgaa cggaugcgac uacguaucca acaagggcgu cgacacaguc uccguuggua     1320

acacccucua cugcgucaac aaacaagaag gccaaucccu auacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccagugacga auuugacgcc uccaucuccc     1440

aagucaacga aaagaucaac caaucccuug ccuucauacg caaauccgac gaacuccuac     1500

acaacguuaa cgccggaaaa ucaacaacca acaucaugau cacaaccauc auaaucguca     1560

uaaucgucau acuccucucc cucauagccg ucggccugcu auuguacugu aaagcccgcu     1620

ccacaccagu cacacuuuca aaagaccaac ucuccgggau caacaacauc gccuucucca     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  3361
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3361
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3362
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3362
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3363
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3363
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3364
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3364
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg aucaauaaca uugcauucag caauugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3365
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3365
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3366
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3366
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga aucaauaaca ucgcuuucag caauugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3367
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3367
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacuaaaa gccaaugcca uaaccacuau ucuaacagca      120

guaacauucu guuucgccuc aggacaaaac auaacagaag aauuuuauca auccaccugu      180

uccgcagucu cgaaaggcua ccuuggcgca cuaagaaccg gaugguauac aucaguaaua      240

accauugaac uaucaaauau caaagaaaua aaaugcaacg gaacugacgc aaaagucaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgccguua cagacuuaca acuacuaaug      360

caaucaacuc cagcaacagg aucaggaucu gcuauaugcu caggugucgc cguauguaaa      420

guguuacacc ucgaaggcga aguaaacaaa auaaaaucag cacuacuauc cacaaauaaa      480

gcaguaguau cacuauccaa ugguguauca guacucacau ucaaaguacu agacuuaaaa      540

aauuauauag auaaacaauu acuaccaaua uuaaacaaac aaucaugcuc aauaccaaac      600

auagaaaccg ucauugaauu ucaacaaaaa aacaaucgac uucuugaaau aacacgagaa      660

uuuucaguaa augccggagu aacaacccca gucucaacau acauguuaac caacucugaa      720

cuccuaagcc uaaucaacga caugcccaua acuaacgacc aaaaaaaacu aauguccaau      780

aauguccaaa uaguaagaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cucgccuaug uaguacaacu acccuuauac ggaguaauug acacaccaug uuggaaacua      900

cauacaucac cacuaugcac cacuaacaca aaagaaggcu ccaacauaug ccuaacccga      960

acagaucgcg gaugguauug cgacaacgca ggaaguguau ccuucuuucc acaagcagaa     1020

acaugcaaag uacaauccaa cagaguauuc ugugacacca ugaacucucu aacacuaccu     1080

uccgaaguaa auuuaugcaa cguagacaua uuuaauccca aauacgacug uaaaauaaug     1140

accucaaaaa cugaugucuc aucaucaguc auuacaucac ucggagcaau agucaguugc     1200

uauggaaaaa ccaaaugcac agcuaguaac aaaaacaggg guauaauaaa aacauuuuca     1260

aacggaugcg auuacguauc aaauaaagga guagacaccg uauccguagg aaauacucuc     1320

uacugcguaa acaaacaaga aggacaaucc cuauacguaa aaggcgaacc aaucauuaac     1380

uuuuacgacc cacuuguauu uccaucagac gaauuugaug ccucaauauc ccaagucaau     1440

gaaaaaauaa accaaagucu agcauucauc cgaaaaucag augaacuuuu acacaacgua     1500

aacgccggaa aaucaacaac aaacaucaug aucacaacaa ucaucauagu aauaauaguu     1560

auacuacuuu ccuuaauagc agucggccua cuacucuacu gcaaagcacg auccacacca     1620

guaaccuuau cuaaagacca acucucaggc auaaacaaca uagcauucuc aaacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3368
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3368
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gcaaacgcca ucacaaccau ccucacagca      120

gucacuuucu gcuucgcauc cggacaaaac aucacagaag aguucuauca auccacgugc      180

uccgcaguuu ccaaaggaua ccuuggagcc uuacgaaccg gcugguacac cuccgucauc      240

accauagaac ucagcaacau caaagaaauc aaaugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aacgcaguca ccgaccucca acuacucaug      360

caaucaaccc ccgcaaccgg cuccggcucc gccaucugcu ccggaguagc cguaugcaaa      420

guccuccacc ucgaaggcga aguuaacaag aucaaguccg cacuccuauc aaccaacaaa      480

gcagucgucu cccuauccaa cggcgucucc guauuaacau ucaaaguccu cgaccucaaa      540

aacuacauag acaaacagcu acuccccauc cuaaacaaac aauccugcuc cauccccaac      600

aucgaaacug ucaucgaguu ccaacagaaa aacaaccgcc uccuagaaau cacccgagag      660

uucuccguaa acgccggcgu cacuaccccc gucucuaccu auaugcuaac caacucugaa      720

cuccuauccc uaaucaacga uaugcccaua acuaacgacc aaaagaaacu uauguccaac      780

aacguacaaa uaguccggca acaaucauac ucuaucaugu gcaucaucaa agaagaagua      840

cuugccuacg uuguccaacu cccacuauac ggcgucauag acacuccaug cuggaaacuu      900

cacaccucac cccucugcac cacuaacacu aaagaaggcu cuaacaucug ccuuacccgc      960

accgaccgcg gaugguacug cgacaacgca ggcucaguua gcuucuuccc acaagccgaa     1020

accugcaaag uccagucaaa ccgugucuuc ugcgauacca ugaacucgcu cacccucccu     1080

uccgaaguca accucugcaa cgucgacauc uucaacccca aauacgacug caaaaucaug     1140

accucaaaaa ccgacguauc uucuuccguc aucaccuccc ucggcgccau cguauccugc     1200

uacggcaaaa ccaaaugcac ugcaucaaac aaaaaccgag gcaucaucaa aaccuucucg     1260

aacggaugcg acuacguauc caacaagggc gucgacacag ucuccguugg uaacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cuauacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccagugac gaauuugacg ccuccaucuc ccaagucaac     1440

gaaaagauca accaaucccu ugccuucaua cgcaaauccg acgaacuccu acacaacguu     1500

aacgccggaa aaucaacaac caacaucaug aucacaacca ucauaaucgu cauaaucguc     1560

auacuccucu cccucauagc cgucggccug cuauuguacu guaaagcccg cuccacacca     1620

gucacacuuu caaaagacca acucuccggg aucaacaaca ucgccuucuc caacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  3369
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3369
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3370
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3370
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg guccaccccc     1620

gugacccuga gcaaggacca gcucuccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3371
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3371
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3372
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3372
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cucaacaccc     1620

gugacccuga guaaagauca acucucuggg aucaauaaca uugcauucag caauugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3373
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3373
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3374
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3374
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag aagcacaccc     1620

gugacccuuu cuaaagauca acucuccgga aucaauaaca ucgcuuucag caauugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3375
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3375
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacuaaaa gccaaugcca uaaccacuau ucuaacagca      120

guaacauucu guuucgccuc aggacaaaac auaacagaag aauuuuauca auccaccugu      180

uccgcagucu cgaaaggcua ccuuggcgca cuaagaaccg gaugguauac aucaguaaua      240

accauugaac uaucaaauau caaagaaaua aaaugcaacg gaacugacgc aaaagucaaa      300

cuaauaaaac aagaauuaga caaauacaaa aacgccguua cagacuuaca acuacuaaug      360

caaucaacuc cagcaacagg aucaggaucu gcuauaugcu caggugucgc cguauguaaa      420

guguuacacc ucgaaggcga aguaaacaaa auaaaaucag cacuacuauc cacaaauaaa      480

gcaguaguau cacuauccaa ugguguauca guacucacau ucaaaguacu agacuuaaaa      540

aauuauauag auaaacaauu acuaccaaua uuaaacaaac aaucaugcuc aauaccaaac      600

auagaaaccg ucauugaauu ucaacaaaaa aacaaucgac uucuugaaau aacacgagaa      660

uuuucaguaa augccggagu aacaacccca gucucaacau acauguuaac caacucugaa      720

cuccuaagcc uaaucaacga caugcccaua acuaacgacc aaaaaaaacu aauguccaau      780

aauguccaaa uaguaagaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cucgccuaug uaguacaacu acccuuauac ggaguaauug acacaccaug uuggaaacua      900

cauacaucac cacuaugcac cacuaacaca aaagaaggcu ccaacauaug ccuaacccga      960

acagaucgcg gaugguauug cgacaacgca ggaaguguau ccuucuuucc acaagcagaa     1020

acaugcaaag uacaauccaa cagaguauuc ugugacacca ugaacucucu aacacuaccu     1080

uccgaaguaa auuuaugcaa cguagacaua uuuaauccca aauacgacug uaaaauaaug     1140

accucaaaaa cugaugucuc aucaucaguc auuacaucac ucggagcaau agucaguugc     1200

uauggaaaaa ccaaaugcac agcuaguaac aaaaacaggg guauaauaaa aacauuuuca     1260

aacggaugcg auuacguauc aaauaaagga guagacaccg uauccguagg aaauacucuc     1320

uacugcguaa acaaacaaga aggacaaucc cuauacguaa aaggcgaacc aaucauuaac     1380

uuuuacgacc cacuuguauu uccaucagac gaauuugaug ccucaauauc ccaagucaau     1440

gaaaaaauaa accaaagucu agcauucauc cgaaaaucag augaacuuuu acacaacgua     1500

aacgccggaa aaucaacaac aaacaucaug aucacaacaa ucaucauagu aauaauaguu     1560

auacuacuuu ccuuaauagc agucggccua cuacucuacu gcaaagcacg auccacacca     1620

guaaccuuau cuaaagacca acucucaggc auaaacaaca uagcauucuc aaacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3376
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3376
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gcaaacgcca ucacaaccau ccucacagca      120

gucacuuucu gcuucgcauc cggacaaaac aucacagaag aguucuauca auccacgugc      180

uccgcaguuu ccaaaggaua ccuuggagcc uuacgaaccg gcugguacac cuccgucauc      240

accauagaac ucagcaacau caaagaaauc aaaugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaaa aacgcaguca ccgaccucca acuacucaug      360

caaucaaccc ccgcaaccgg cuccggcucc gccaucugcu ccggaguagc cguaugcaaa      420

guccuccacc ucgaaggcga aguuaacaag aucaaguccg cacuccuauc aaccaacaaa      480

gcagucgucu cccuauccaa cggcgucucc guauuaacau ucaaaguccu cgaccucaaa      540

aacuacauag acaaacagcu acuccccauc cuaaacaaac aauccugcuc cauccccaac      600

aucgaaacug ucaucgaguu ccaacagaaa aacaaccgcc uccuagaaau cacccgagag      660

uucuccguaa acgccggcgu cacuaccccc gucucuaccu auaugcuaac caacucugaa      720

cuccuauccc uaaucaacga uaugcccaua acuaacgacc aaaagaaacu uauguccaac      780

aacguacaaa uaguccggca acaaucauac ucuaucaugu gcaucaucaa agaagaagua      840

cuugccuacg uuguccaacu cccacuauac ggcgucauag acacuccaug cuggaaacuu      900

cacaccucac cccucugcac cacuaacacu aaagaaggcu cuaacaucug ccuuacccgc      960

accgaccgcg gaugguacug cgacaacgca ggcucaguua gcuucuuccc acaagccgaa     1020

accugcaaag uccagucaaa ccgugucuuc ugcgauacca ugaacucgcu cacccucccu     1080

uccgaaguca accucugcaa cgucgacauc uucaacccca aauacgacug caaaaucaug     1140

accucaaaaa ccgacguauc uucuuccguc aucaccuccc ucggcgccau cguauccugc     1200

uacggcaaaa ccaaaugcac ugcaucaaac aaaaaccgag gcaucaucaa aaccuucucg     1260

aacggaugcg acuacguauc caacaagggc gucgacacag ucuccguugg uaacacccuc     1320

uacugcguca acaaacaaga aggccaaucc cuauacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccagugac gaauuugacg ccuccaucuc ccaagucaac     1440

gaaaagauca accaaucccu ugccuucaua cgcaaauccg acgaacuccu acacaacguu     1500

aacgccggaa aaucaacaac caacaucaug aucacaacca ucauaaucgu cauaaucguc     1560

auacuccucu cccucauagc cgucggccug cuauuguacu guaaagcccg cuccacacca     1620

gucacacuuu caaaagacca acucuccggg aucaacaaca ucgccuucuc caacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  3377
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3377
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3378
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3378
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3379
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3379
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3380
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3380
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggauc     1680

aauaacauug cauucagcaa uugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3381
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3381
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3382
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3382
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauc     1680

aauaacaucg cuuucagcaa uugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3383
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3383
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acuaaaagcc      120

aaugccauaa ccacuauucu aacagcagua acauucuguu ucgccucagg acaaaacaua      180

acagaagaau uuuaucaauc caccuguucc gcagucucga aaggcuaccu uggcgcacua      240

agaaccggau gguauacauc aguaauaacc auugaacuau caaauaucaa agaaauaaaa      300

ugcaacggaa cugacgcaaa agucaaacua auaaaacaag aauuagacaa auacaaaaac      360

gccguuacag acuuacaacu acuaaugcaa ucaacuccag caacaggauc aggaucugcu      420

auaugcucag gugucgccgu auguaaagug uuacaccucg aaggcgaagu aaacaaaaua      480

aaaucagcac uacuauccac aaauaaagca guaguaucac uauccaaugg uguaucagua      540

cucacauuca aaguacuaga cuuaaaaaau uauauagaua aacaauuacu accaauauua      600

aacaaacaau caugcucaau accaaacaua gaaaccguca uugaauuuca acaaaaaaac      660

aaucgacuuc uugaaauaac acgagaauuu ucaguaaaug ccggaguaac aaccccaguc      720

ucaacauaca uguuaaccaa cucugaacuc cuaagccuaa ucaacgacau gcccauaacu      780

aacgaccaaa aaaaacuaau guccaauaau guccaaauag uaagacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccuc gccuauguag uacaacuacc cuuauacgga      900

guaauugaca caccauguug gaaacuacau acaucaccac uaugcaccac uaacacaaaa      960

gaaggcucca acauaugccu aacccgaaca gaucgcggau gguauugcga caacgcagga     1020

aguguauccu ucuuuccaca agcagaaaca ugcaaaguac aauccaacag aguauucugu     1080

gacaccauga acucucuaac acuaccuucc gaaguaaauu uaugcaacgu agacauauuu     1140

aaucccaaau acgacuguaa aauaaugacc ucaaaaacug augucucauc aucagucauu     1200

acaucacucg gagcaauagu caguugcuau ggaaaaacca aaugcacagc uaguaacaaa     1260

aacaggggua uaauaaaaac auuuucaaac ggaugcgauu acguaucaaa uaaaggagua     1320

gacaccguau ccguaggaaa uacucucuac ugcguaaaca aacaagaagg acaaucccua     1380

uacguaaaag gcgaaccaau cauuaacuuu uacgacccac uuguauuucc aucagacgaa     1440

uuugaugccu caauauccca agucaaugaa aaaauaaacc aaagucuagc auucauccga     1500

aaaucagaug aacuuuuaca caacguaaac gccggaaaau caacaacaaa caucaugauc     1560

acaacaauca ucauaguaau aauaguuaua cuacuuuccu uaauagcagu cggccuacua     1620

cucuacugca aagcacgauc cacaccagua accuuaucua aagaccaacu cucaggcaua     1680

aacaacauag cauucucaaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3384
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3384
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagca      120

aacgccauca caaccauccu cacagcaguc acuuucugcu ucgcauccgg acaaaacauc      180

acagaagagu ucuaucaauc cacgugcucc gcaguuucca aaggauaccu uggagccuua      240

cgaaccggcu gguacaccuc cgucaucacc auagaacuca gcaacaucaa agaaaucaaa      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaaaaac      360

gcagucaccg accuccaacu acucaugcaa ucaacccccg caaccggcuc cggcuccgcc      420

aucugcuccg gaguagccgu augcaaaguc cuccaccucg aaggcgaagu uaacaagauc      480

aaguccgcac uccuaucaac caacaaagca gucgucuccc uauccaacgg cgucuccgua      540

uuaacauuca aaguccucga ccucaaaaac uacauagaca aacagcuacu ccccauccua      600

aacaaacaau ccugcuccau ccccaacauc gaaacuguca ucgaguucca acagaaaaac      660

aaccgccucc uagaaaucac ccgagaguuc uccguaaacg ccggcgucac uacccccguc      720

ucuaccuaua ugcuaaccaa cucugaacuc cuaucccuaa ucaacgauau gcccauaacu      780

aacgaccaaa agaaacuuau guccaacaac guacaaauag uccggcaaca aucauacucu      840

aucaugugca ucaucaaaga agaaguacuu gccuacguug uccaacuccc acuauacggc      900

gucauagaca cuccaugcug gaaacuucac accucacccc ucugcaccac uaacacuaaa      960

gaaggcucua acaucugccu uacccgcacc gaccgcggau gguacugcga caacgcaggc     1020

ucaguuagcu ucuucccaca agccgaaacc ugcaaagucc agucaaaccg ugucuucugc     1080

gauaccauga acucgcucac ccucccuucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucaaaaaccg acguaucuuc uuccgucauc     1200

accucccucg gcgccaucgu auccugcuac ggcaaaacca aaugcacugc aucaaacaaa     1260

aaccgaggca ucaucaaaac cuucucgaac ggaugcgacu acguauccaa caagggcguc     1320

gacacagucu ccguugguaa cacccucuac ugcgucaaca aacaagaagg ccaaucccua     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cagugacgaa     1440

uuugacgccu ccaucuccca agucaacgaa aagaucaacc aaucccuugc cuucauacgc     1500

aaauccgacg aacuccuaca caacguuaac gccggaaaau caacaaccaa caucaugauc     1560

acaaccauca uaaucgucau aaucgucaua cuccucuccc ucauagccgu cggccugcua     1620

uuguacugua aagcccgcuc cacaccaguc acacuuucaa aagaccaacu cuccgggauc     1680

aacaacaucg ccuucuccaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  3385
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3385
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3386
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3386
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccgguc cacccccgug acccugagca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3387
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3387
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3388
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3388
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcuc aacacccgug acccugagua aagaucaacu cucugggauc     1680

aauaacauug cauucagcaa uugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3389
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3389
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3390
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3390
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaag cacacccgug acccuuucua aagaucaacu cuccggaauc     1680

aauaacaucg cuuucagcaa uugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3391
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3391
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acuaaaagcc      120

aaugccauaa ccacuauucu aacagcagua acauucuguu ucgccucagg acaaaacaua      180

acagaagaau uuuaucaauc caccuguucc gcagucucga aaggcuaccu uggcgcacua      240

agaaccggau gguauacauc aguaauaacc auugaacuau caaauaucaa agaaauaaaa      300

ugcaacggaa cugacgcaaa agucaaacua auaaaacaag aauuagacaa auacaaaaac      360

gccguuacag acuuacaacu acuaaugcaa ucaacuccag caacaggauc aggaucugcu      420

auaugcucag gugucgccgu auguaaagug uuacaccucg aaggcgaagu aaacaaaaua      480

aaaucagcac uacuauccac aaauaaagca guaguaucac uauccaaugg uguaucagua      540

cucacauuca aaguacuaga cuuaaaaaau uauauagaua aacaauuacu accaauauua      600

aacaaacaau caugcucaau accaaacaua gaaaccguca uugaauuuca acaaaaaaac      660

aaucgacuuc uugaaauaac acgagaauuu ucaguaaaug ccggaguaac aaccccaguc      720

ucaacauaca uguuaaccaa cucugaacuc cuaagccuaa ucaacgacau gcccauaacu      780

aacgaccaaa aaaaacuaau guccaauaau guccaaauag uaagacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccuc gccuauguag uacaacuacc cuuauacgga      900

guaauugaca caccauguug gaaacuacau acaucaccac uaugcaccac uaacacaaaa      960

gaaggcucca acauaugccu aacccgaaca gaucgcggau gguauugcga caacgcagga     1020

aguguauccu ucuuuccaca agcagaaaca ugcaaaguac aauccaacag aguauucugu     1080

gacaccauga acucucuaac acuaccuucc gaaguaaauu uaugcaacgu agacauauuu     1140

aaucccaaau acgacuguaa aauaaugacc ucaaaaacug augucucauc aucagucauu     1200

acaucacucg gagcaauagu caguugcuau ggaaaaacca aaugcacagc uaguaacaaa     1260

aacaggggua uaauaaaaac auuuucaaac ggaugcgauu acguaucaaa uaaaggagua     1320

gacaccguau ccguaggaaa uacucucuac ugcguaaaca aacaagaagg acaaucccua     1380

uacguaaaag gcgaaccaau cauuaacuuu uacgacccac uuguauuucc aucagacgaa     1440

uuugaugccu caauauccca agucaaugaa aaaauaaacc aaagucuagc auucauccga     1500

aaaucagaug aacuuuuaca caacguaaac gccggaaaau caacaacaaa caucaugauc     1560

acaacaauca ucauaguaau aauaguuaua cuacuuuccu uaauagcagu cggccuacua     1620

cucuacugca aagcacgauc cacaccagua accuuaucua aagaccaacu cucaggcaua     1680

aacaacauag cauucucaaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3392
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3392
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagca      120

aacgccauca caaccauccu cacagcaguc acuuucugcu ucgcauccgg acaaaacauc      180

acagaagagu ucuaucaauc cacgugcucc gcaguuucca aaggauaccu uggagccuua      240

cgaaccggcu gguacaccuc cgucaucacc auagaacuca gcaacaucaa agaaaucaaa      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaaaaac      360

gcagucaccg accuccaacu acucaugcaa ucaacccccg caaccggcuc cggcuccgcc      420

aucugcuccg gaguagccgu augcaaaguc cuccaccucg aaggcgaagu uaacaagauc      480

aaguccgcac uccuaucaac caacaaagca gucgucuccc uauccaacgg cgucuccgua      540

uuaacauuca aaguccucga ccucaaaaac uacauagaca aacagcuacu ccccauccua      600

aacaaacaau ccugcuccau ccccaacauc gaaacuguca ucgaguucca acagaaaaac      660

aaccgccucc uagaaaucac ccgagaguuc uccguaaacg ccggcgucac uacccccguc      720

ucuaccuaua ugcuaaccaa cucugaacuc cuaucccuaa ucaacgauau gcccauaacu      780

aacgaccaaa agaaacuuau guccaacaac guacaaauag uccggcaaca aucauacucu      840

aucaugugca ucaucaaaga agaaguacuu gccuacguug uccaacuccc acuauacggc      900

gucauagaca cuccaugcug gaaacuucac accucacccc ucugcaccac uaacacuaaa      960

gaaggcucua acaucugccu uacccgcacc gaccgcggau gguacugcga caacgcaggc     1020

ucaguuagcu ucuucccaca agccgaaacc ugcaaagucc agucaaaccg ugucuucugc     1080

gauaccauga acucgcucac ccucccuucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucaaaaaccg acguaucuuc uuccgucauc     1200

accucccucg gcgccaucgu auccugcuac ggcaaaacca aaugcacugc aucaaacaaa     1260

aaccgaggca ucaucaaaac cuucucgaac ggaugcgacu acguauccaa caagggcguc     1320

gacacagucu ccguugguaa cacccucuac ugcgucaaca aacaagaagg ccaaucccua     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cagugacgaa     1440

uuugacgccu ccaucuccca agucaacgaa aagaucaacc aaucccuugc cuucauacgc     1500

aaauccgacg aacuccuaca caacguuaac gccggaaaau caacaaccaa caucaugauc     1560

acaaccauca uaaucgucau aaucgucaua cuccucuccc ucauagccgu cggccugcua     1620

uuguacugua aagcccgcuc cacaccaguc acacuuucaa aagaccaacu cuccgggauc     1680

aacaacaucg ccuucuccaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  3393
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3393
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3394
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3394
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc     1680

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3395
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3395
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3396
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3396
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc     1680

cugaguaaag aucaacucuc ugggaucaau aacauugcau ucagcaauug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3397
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3397
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3398
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3398
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc     1680

cuuucuaaag aucaacucuc cggaaucaau aacaucgcuu ucagcaauug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3399
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3399
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu aaaagccaau gccauaacca cuauucuaac agcaguaaca      180

uucuguuucg ccucaggaca aaacauaaca gaagaauuuu aucaauccac cuguuccgca      240

gucucgaaag gcuaccuugg cgcacuaaga accggauggu auacaucagu aauaaccauu      300

gaacuaucaa auaucaaaga aauaaaaugc aacggaacug acgcaaaagu caaacuaaua      360

aaacaagaau uagacaaaua caaaaacgcc guuacagacu uacaacuacu aaugcaauca      420

acuccagcaa caggaucagg aucugcuaua ugcucaggug ucgccguaug uaaaguguua      480

caccucgaag gcgaaguaaa caaaauaaaa ucagcacuac uauccacaaa uaaagcagua      540

guaucacuau ccaauggugu aucaguacuc acauucaaag uacuagacuu aaaaaauuau      600

auagauaaac aauuacuacc aauauuaaac aaacaaucau gcucaauacc aaacauagaa      660

accgucauug aauuucaaca aaaaaacaau cgacuucuug aaauaacacg agaauuuuca      720

guaaaugccg gaguaacaac cccagucuca acauacaugu uaaccaacuc ugaacuccua      780

agccuaauca acgacaugcc cauaacuaac gaccaaaaaa aacuaauguc caauaauguc      840

caaauaguaa gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccucgcc      900

uauguaguac aacuacccuu auacggagua auugacacac cauguuggaa acuacauaca      960

ucaccacuau gcaccacuaa cacaaaagaa ggcuccaaca uaugccuaac ccgaacagau     1020

cgcggauggu auugcgacaa cgcaggaagu guauccuucu uuccacaagc agaaacaugc     1080

aaaguacaau ccaacagagu auucugugac accaugaacu cucuaacacu accuuccgaa     1140

guaaauuuau gcaacguaga cauauuuaau cccaaauacg acuguaaaau aaugaccuca     1200

aaaacugaug ucucaucauc agucauuaca ucacucggag caauagucag uugcuaugga     1260

aaaaccaaau gcacagcuag uaacaaaaac agggguauaa uaaaaacauu uucaaacgga     1320

ugcgauuacg uaucaaauaa aggaguagac accguauccg uaggaaauac ucucuacugc     1380

guaaacaaac aagaaggaca aucccuauac guaaaaggcg aaccaaucau uaacuuuuac     1440

gacccacuug uauuuccauc agacgaauuu gaugccucaa uaucccaagu caaugaaaaa     1500

auaaaccaaa gucuagcauu cauccgaaaa ucagaugaac uuuuacacaa cguaaacgcc     1560

ggaaaaucaa caacaaacau caugaucaca acaaucauca uaguaauaau aguuauacua     1620

cuuuccuuaa uagcagucgg ccuacuacuc uacugcaaag cacgauccac accaguaacc     1680

uuaucuaaag accaacucuc aggcauaaac aacauagcau ucucaaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3400
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3400
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagcaaac gccaucacaa ccauccucac agcagucacu      180

uucugcuucg cauccggaca aaacaucaca gaagaguucu aucaauccac gugcuccgca      240

guuuccaaag gauaccuugg agccuuacga accggcuggu acaccuccgu caucaccaua      300

gaacucagca acaucaaaga aaucaaaugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caaaaacgca gucaccgacc uccaacuacu caugcaauca      420

acccccgcaa ccggcuccgg cuccgccauc ugcuccggag uagccguaug caaaguccuc      480

caccucgaag gcgaaguuaa caagaucaag uccgcacucc uaucaaccaa caaagcaguc      540

gucucccuau ccaacggcgu cuccguauua acauucaaag uccucgaccu caaaaacuac      600

auagacaaac agcuacuccc cauccuaaac aaacaauccu gcuccauccc caacaucgaa      660

acugucaucg aguuccaaca gaaaaacaac cgccuccuag aaaucacccg agaguucucc      720

guaaacgccg gcgucacuac ccccgucucu accuauaugc uaaccaacuc ugaacuccua      780

ucccuaauca acgauaugcc cauaacuaac gaccaaaaga aacuuauguc caacaacgua      840

caaauagucc ggcaacaauc auacucuauc augugcauca ucaaagaaga aguacuugcc      900

uacguugucc aacucccacu auacggcguc auagacacuc caugcuggaa acuucacacc      960

ucaccccucu gcaccacuaa cacuaaagaa ggcucuaaca ucugccuuac ccgcaccgac     1020

cgcggauggu acugcgacaa cgcaggcuca guuagcuucu ucccacaagc cgaaaccugc     1080

aaaguccagu caaaccgugu cuucugcgau accaugaacu cgcucacccu cccuuccgaa     1140

gucaaccucu gcaacgucga caucuucaac cccaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg uaucuucuuc cgucaucacc ucccucggcg ccaucguauc cugcuacggc     1260

aaaaccaaau gcacugcauc aaacaaaaac cgaggcauca ucaaaaccuu cucgaacgga     1320

ugcgacuacg uauccaacaa gggcgucgac acagucuccg uugguaacac ccucuacugc     1380

gucaacaaac aagaaggcca aucccuauac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccag ugacgaauuu gacgccucca ucucccaagu caacgaaaag     1500

aucaaccaau cccuugccuu cauacgcaaa uccgacgaac uccuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaacau caugaucaca accaucauaa ucgucauaau cgucauacuc     1620

cucucccuca uagccgucgg ccugcuauug uacuguaaag cccgcuccac accagucaca     1680

cuuucaaaag accaacucuc cgggaucaac aacaucgccu ucuccaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3401
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3401
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3402
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3402
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3403
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3403
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3404
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3404
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

aucaauaaca uugcauucag caauugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3405
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3405
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3406
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3406
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

aucaauaaca ucgcuuucag caauugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3407
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3407
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacuaaaa      120

gccaaugcca uaaccacuau ucuaacagca guaacauucu guuucgccuc aggacaaaac      180

auaacagaag aauuuuauca auccaccugu uccgcagucu cgaaaggcua ccuuggcgca      240

cuaagaaccg gaugguauac aucaguaaua accauugaac uaucaaauau caaagaaaua      300

aaaugcaacg gaacugacgc aaaagucaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgccguua cagacuuaca acuacuaaug caaucaacuc cagcaacagg aucaggaucu      420

gcuauaugcu caggugucgc cguauguaaa guguuacacc ucgaaggcga aguaaacaaa      480

auaaaaucag cacuacuauc cacaaauaaa gcaguaguau cacuauccaa ugguguauca      540

guacucacau ucaaaguacu agacuuaaaa aauuauauag auaaacaauu acuaccaaua      600

uuaaacaaac aaucaugcuc aauaccaaac auagaaaccg ucauugaauu ucaacaaaaa      660

aacaaucgac uucuugaaau aacacgagaa uuuucaguaa augccggagu aacaacccca      720

gucucaacau acauguuaac caacucugaa cuccuaagcc uaaucaacga caugcccaua      780

acuaacgacc aaaaaaaacu aauguccaau aauguccaaa uaguaagaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cucgccuaug uaguacaacu acccuuauac      900

ggaguaauug acacaccaug uuggaaacua cauacaucac cacuaugcac cacuaacaca      960

aaagaaggcu ccaacauaug ccuaacccga acagaucgcg gaugguauug cgacaacgca     1020

ggaaguguau ccuucuuucc acaagcagaa acaugcaaag uacaauccaa cagaguauuc     1080

ugugacacca ugaacucucu aacacuaccu uccgaaguaa auuuaugcaa cguagacaua     1140

uuuaauccca aauacgacug uaaaauaaug accucaaaaa cugaugucuc aucaucaguc     1200

auuacaucac ucggagcaau agucaguugc uauggaaaaa ccaaaugcac agcuaguaac     1260

aaaaacaggg guauaauaaa aacauuuuca aacggaugcg auuacguauc aaauaaagga     1320

guagacaccg uauccguagg aaauacucuc uacugcguaa acaaacaaga aggacaaucc     1380

cuauacguaa aaggcgaacc aaucauuaac uuuuacgacc cacuuguauu uccaucagac     1440

gaauuugaug ccucaauauc ccaagucaau gaaaaaauaa accaaagucu agcauucauc     1500

cgaaaaucag augaacuuuu acacaacgua aacgccggaa aaucaacaac aaacaucaug     1560

aucacaacaa ucaucauagu aauaauaguu auacuacuuu ccuuaauagc agucggccua     1620

cuacucuacu gcaaagcacg auccacacca guaaccuuau cuaaagacca acucucaggc     1680

auaaacaaca uagcauucuc aaacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3408
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3408
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gcaaacgcca ucacaaccau ccucacagca gucacuuucu gcuucgcauc cggacaaaac      180

aucacagaag aguucuauca auccacgugc uccgcaguuu ccaaaggaua ccuuggagcc      240

uuacgaaccg gcugguacac cuccgucauc accauagaac ucagcaacau caaagaaauc      300

aaaugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaccucca acuacucaug caaucaaccc ccgcaaccgg cuccggcucc      420

gccaucugcu ccggaguagc cguaugcaaa guccuccacc ucgaaggcga aguuaacaag      480

aucaaguccg cacuccuauc aaccaacaaa gcagucgucu cccuauccaa cggcgucucc      540

guauuaacau ucaaaguccu cgaccucaaa aacuacauag acaaacagcu acuccccauc      600

cuaaacaaac aauccugcuc cauccccaac aucgaaacug ucaucgaguu ccaacagaaa      660

aacaaccgcc uccuagaaau cacccgagag uucuccguaa acgccggcgu cacuaccccc      720

gucucuaccu auaugcuaac caacucugaa cuccuauccc uaaucaacga uaugcccaua      780

acuaacgacc aaaagaaacu uauguccaac aacguacaaa uaguccggca acaaucauac      840

ucuaucaugu gcaucaucaa agaagaagua cuugccuacg uuguccaacu cccacuauac      900

ggcgucauag acacuccaug cuggaaacuu cacaccucac cccucugcac cacuaacacu      960

aaagaaggcu cuaacaucug ccuuacccgc accgaccgcg gaugguacug cgacaacgca     1020

ggcucaguua gcuucuuccc acaagccgaa accugcaaag uccagucaaa ccgugucuuc     1080

ugcgauacca ugaacucgcu cacccucccu uccgaaguca accucugcaa cgucgacauc     1140

uucaacccca aauacgacug caaaaucaug accucaaaaa ccgacguauc uucuuccguc     1200

aucaccuccc ucggcgccau cguauccugc uacggcaaaa ccaaaugcac ugcaucaaac     1260

aaaaaccgag gcaucaucaa aaccuucucg aacggaugcg acuacguauc caacaagggc     1320

gucgacacag ucuccguugg uaacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cuauacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagugac     1440

gaauuugacg ccuccaucuc ccaagucaac gaaaagauca accaaucccu ugccuucaua     1500

cgcaaauccg acgaacuccu acacaacguu aacgccggaa aaucaacaac caacaucaug     1560

aucacaacca ucauaaucgu cauaaucguc auacuccucu cccucauagc cgucggccug     1620

cuauuguacu guaaagcccg cuccacacca gucacacuuu caaaagacca acucuccggg     1680

aucaacaaca ucgccuucuc caacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  3409
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3409
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3410
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3410
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3411
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3411
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3412
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3412
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

aucaauaaca uugcauucag caauugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3413
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3413
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3414
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3414
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

aucaauaaca ucgcuuucag caauugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3415
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3415
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacuaaaa      120

gccaaugcca uaaccacuau ucuaacagca guaacauucu guuucgccuc aggacaaaac      180

auaacagaag aauuuuauca auccaccugu uccgcagucu cgaaaggcua ccuuggcgca      240

cuaagaaccg gaugguauac aucaguaaua accauugaac uaucaaauau caaagaaaua      300

aaaugcaacg gaacugacgc aaaagucaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgccguua cagacuuaca acuacuaaug caaucaacuc cagcaacagg aucaggaucu      420

gcuauaugcu caggugucgc cguauguaaa guguuacacc ucgaaggcga aguaaacaaa      480

auaaaaucag cacuacuauc cacaaauaaa gcaguaguau cacuauccaa ugguguauca      540

guacucacau ucaaaguacu agacuuaaaa aauuauauag auaaacaauu acuaccaaua      600

uuaaacaaac aaucaugcuc aauaccaaac auagaaaccg ucauugaauu ucaacaaaaa      660

aacaaucgac uucuugaaau aacacgagaa uuuucaguaa augccggagu aacaacccca      720

gucucaacau acauguuaac caacucugaa cuccuaagcc uaaucaacga caugcccaua      780

acuaacgacc aaaaaaaacu aauguccaau aauguccaaa uaguaagaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cucgccuaug uaguacaacu acccuuauac      900

ggaguaauug acacaccaug uuggaaacua cauacaucac cacuaugcac cacuaacaca      960

aaagaaggcu ccaacauaug ccuaacccga acagaucgcg gaugguauug cgacaacgca     1020

ggaaguguau ccuucuuucc acaagcagaa acaugcaaag uacaauccaa cagaguauuc     1080

ugugacacca ugaacucucu aacacuaccu uccgaaguaa auuuaugcaa cguagacaua     1140

uuuaauccca aauacgacug uaaaauaaug accucaaaaa cugaugucuc aucaucaguc     1200

auuacaucac ucggagcaau agucaguugc uauggaaaaa ccaaaugcac agcuaguaac     1260

aaaaacaggg guauaauaaa aacauuuuca aacggaugcg auuacguauc aaauaaagga     1320

guagacaccg uauccguagg aaauacucuc uacugcguaa acaaacaaga aggacaaucc     1380

cuauacguaa aaggcgaacc aaucauuaac uuuuacgacc cacuuguauu uccaucagac     1440

gaauuugaug ccucaauauc ccaagucaau gaaaaaauaa accaaagucu agcauucauc     1500

cgaaaaucag augaacuuuu acacaacgua aacgccggaa aaucaacaac aaacaucaug     1560

aucacaacaa ucaucauagu aauaauaguu auacuacuuu ccuuaauagc agucggccua     1620

cuacucuacu gcaaagcacg auccacacca guaaccuuau cuaaagacca acucucaggc     1680

auaaacaaca uagcauucuc aaacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3416
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3416
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gcaaacgcca ucacaaccau ccucacagca gucacuuucu gcuucgcauc cggacaaaac      180

aucacagaag aguucuauca auccacgugc uccgcaguuu ccaaaggaua ccuuggagcc      240

uuacgaaccg gcugguacac cuccgucauc accauagaac ucagcaacau caaagaaauc      300

aaaugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaccucca acuacucaug caaucaaccc ccgcaaccgg cuccggcucc      420

gccaucugcu ccggaguagc cguaugcaaa guccuccacc ucgaaggcga aguuaacaag      480

aucaaguccg cacuccuauc aaccaacaaa gcagucgucu cccuauccaa cggcgucucc      540

guauuaacau ucaaaguccu cgaccucaaa aacuacauag acaaacagcu acuccccauc      600

cuaaacaaac aauccugcuc cauccccaac aucgaaacug ucaucgaguu ccaacagaaa      660

aacaaccgcc uccuagaaau cacccgagag uucuccguaa acgccggcgu cacuaccccc      720

gucucuaccu auaugcuaac caacucugaa cuccuauccc uaaucaacga uaugcccaua      780

acuaacgacc aaaagaaacu uauguccaac aacguacaaa uaguccggca acaaucauac      840

ucuaucaugu gcaucaucaa agaagaagua cuugccuacg uuguccaacu cccacuauac      900

ggcgucauag acacuccaug cuggaaacuu cacaccucac cccucugcac cacuaacacu      960

aaagaaggcu cuaacaucug ccuuacccgc accgaccgcg gaugguacug cgacaacgca     1020

ggcucaguua gcuucuuccc acaagccgaa accugcaaag uccagucaaa ccgugucuuc     1080

ugcgauacca ugaacucgcu cacccucccu uccgaaguca accucugcaa cgucgacauc     1140

uucaacccca aauacgacug caaaaucaug accucaaaaa ccgacguauc uucuuccguc     1200

aucaccuccc ucggcgccau cguauccugc uacggcaaaa ccaaaugcac ugcaucaaac     1260

aaaaaccgag gcaucaucaa aaccuucucg aacggaugcg acuacguauc caacaagggc     1320

gucgacacag ucuccguugg uaacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cuauacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagugac     1440

gaauuugacg ccuccaucuc ccaagucaac gaaaagauca accaaucccu ugccuucaua     1500

cgcaaauccg acgaacuccu acacaacguu aacgccggaa aaucaacaac caacaucaug     1560

aucacaacca ucauaaucgu cauaaucguc auacuccucu cccucauagc cgucggccug     1620

cuauuguacu guaaagcccg cuccacacca gucacacuuu caaaagacca acucuccggg     1680

aucaacaaca ucgccuucuc caacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  3417
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3417
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3418
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3418
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3419
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3419
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3420
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3420
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

aucaauaaca uugcauucag caauugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3421
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3421
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3422
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3422
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

aucaauaaca ucgcuuucag caauugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3423
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3423
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacuaaaa      120

gccaaugcca uaaccacuau ucuaacagca guaacauucu guuucgccuc aggacaaaac      180

auaacagaag aauuuuauca auccaccugu uccgcagucu cgaaaggcua ccuuggcgca      240

cuaagaaccg gaugguauac aucaguaaua accauugaac uaucaaauau caaagaaaua      300

aaaugcaacg gaacugacgc aaaagucaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgccguua cagacuuaca acuacuaaug caaucaacuc cagcaacagg aucaggaucu      420

gcuauaugcu caggugucgc cguauguaaa guguuacacc ucgaaggcga aguaaacaaa      480

auaaaaucag cacuacuauc cacaaauaaa gcaguaguau cacuauccaa ugguguauca      540

guacucacau ucaaaguacu agacuuaaaa aauuauauag auaaacaauu acuaccaaua      600

uuaaacaaac aaucaugcuc aauaccaaac auagaaaccg ucauugaauu ucaacaaaaa      660

aacaaucgac uucuugaaau aacacgagaa uuuucaguaa augccggagu aacaacccca      720

gucucaacau acauguuaac caacucugaa cuccuaagcc uaaucaacga caugcccaua      780

acuaacgacc aaaaaaaacu aauguccaau aauguccaaa uaguaagaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cucgccuaug uaguacaacu acccuuauac      900

ggaguaauug acacaccaug uuggaaacua cauacaucac cacuaugcac cacuaacaca      960

aaagaaggcu ccaacauaug ccuaacccga acagaucgcg gaugguauug cgacaacgca     1020

ggaaguguau ccuucuuucc acaagcagaa acaugcaaag uacaauccaa cagaguauuc     1080

ugugacacca ugaacucucu aacacuaccu uccgaaguaa auuuaugcaa cguagacaua     1140

uuuaauccca aauacgacug uaaaauaaug accucaaaaa cugaugucuc aucaucaguc     1200

auuacaucac ucggagcaau agucaguugc uauggaaaaa ccaaaugcac agcuaguaac     1260

aaaaacaggg guauaauaaa aacauuuuca aacggaugcg auuacguauc aaauaaagga     1320

guagacaccg uauccguagg aaauacucuc uacugcguaa acaaacaaga aggacaaucc     1380

cuauacguaa aaggcgaacc aaucauuaac uuuuacgacc cacuuguauu uccaucagac     1440

gaauuugaug ccucaauauc ccaagucaau gaaaaaauaa accaaagucu agcauucauc     1500

cgaaaaucag augaacuuuu acacaacgua aacgccggaa aaucaacaac aaacaucaug     1560

aucacaacaa ucaucauagu aauaauaguu auacuacuuu ccuuaauagc agucggccua     1620

cuacucuacu gcaaagcacg auccacacca guaaccuuau cuaaagacca acucucaggc     1680

auaaacaaca uagcauucuc aaacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3424
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3424
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gcaaacgcca ucacaaccau ccucacagca gucacuuucu gcuucgcauc cggacaaaac      180

aucacagaag aguucuauca auccacgugc uccgcaguuu ccaaaggaua ccuuggagcc      240

uuacgaaccg gcugguacac cuccgucauc accauagaac ucagcaacau caaagaaauc      300

aaaugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaccucca acuacucaug caaucaaccc ccgcaaccgg cuccggcucc      420

gccaucugcu ccggaguagc cguaugcaaa guccuccacc ucgaaggcga aguuaacaag      480

aucaaguccg cacuccuauc aaccaacaaa gcagucgucu cccuauccaa cggcgucucc      540

guauuaacau ucaaaguccu cgaccucaaa aacuacauag acaaacagcu acuccccauc      600

cuaaacaaac aauccugcuc cauccccaac aucgaaacug ucaucgaguu ccaacagaaa      660

aacaaccgcc uccuagaaau cacccgagag uucuccguaa acgccggcgu cacuaccccc      720

gucucuaccu auaugcuaac caacucugaa cuccuauccc uaaucaacga uaugcccaua      780

acuaacgacc aaaagaaacu uauguccaac aacguacaaa uaguccggca acaaucauac      840

ucuaucaugu gcaucaucaa agaagaagua cuugccuacg uuguccaacu cccacuauac      900

ggcgucauag acacuccaug cuggaaacuu cacaccucac cccucugcac cacuaacacu      960

aaagaaggcu cuaacaucug ccuuacccgc accgaccgcg gaugguacug cgacaacgca     1020

ggcucaguua gcuucuuccc acaagccgaa accugcaaag uccagucaaa ccgugucuuc     1080

ugcgauacca ugaacucgcu cacccucccu uccgaaguca accucugcaa cgucgacauc     1140

uucaacccca aauacgacug caaaaucaug accucaaaaa ccgacguauc uucuuccguc     1200

aucaccuccc ucggcgccau cguauccugc uacggcaaaa ccaaaugcac ugcaucaaac     1260

aaaaaccgag gcaucaucaa aaccuucucg aacggaugcg acuacguauc caacaagggc     1320

gucgacacag ucuccguugg uaacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cuauacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagugac     1440

gaauuugacg ccuccaucuc ccaagucaac gaaaagauca accaaucccu ugccuucaua     1500

cgcaaauccg acgaacuccu acacaacguu aacgccggaa aaucaacaac caacaucaug     1560

aucacaacca ucauaaucgu cauaaucguc auacuccucu cccucauagc cgucggccug     1620

cuauuguacu guaaagcccg cuccacacca gucacacuuu caaaagacca acucuccggg     1680

aucaacaaca ucgccuucuc caacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  3425
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3425
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3426
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3426
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3427
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3427
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3428
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3428
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cucaacaccc gugacccuga guaaagauca acucucuggg     1680

aucaauaaca uugcauucag caauugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3429
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3429
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3430
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3430
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag aagcacaccc gugacccuuu cuaaagauca acucuccgga     1680

aucaauaaca ucgcuuucag caauugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3431
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3431
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacuaaaa      120

gccaaugcca uaaccacuau ucuaacagca guaacauucu guuucgccuc aggacaaaac      180

auaacagaag aauuuuauca auccaccugu uccgcagucu cgaaaggcua ccuuggcgca      240

cuaagaaccg gaugguauac aucaguaaua accauugaac uaucaaauau caaagaaaua      300

aaaugcaacg gaacugacgc aaaagucaaa cuaauaaaac aagaauuaga caaauacaaa      360

aacgccguua cagacuuaca acuacuaaug caaucaacuc cagcaacagg aucaggaucu      420

gcuauaugcu caggugucgc cguauguaaa guguuacacc ucgaaggcga aguaaacaaa      480

auaaaaucag cacuacuauc cacaaauaaa gcaguaguau cacuauccaa ugguguauca      540

guacucacau ucaaaguacu agacuuaaaa aauuauauag auaaacaauu acuaccaaua      600

uuaaacaaac aaucaugcuc aauaccaaac auagaaaccg ucauugaauu ucaacaaaaa      660

aacaaucgac uucuugaaau aacacgagaa uuuucaguaa augccggagu aacaacccca      720

gucucaacau acauguuaac caacucugaa cuccuaagcc uaaucaacga caugcccaua      780

acuaacgacc aaaaaaaacu aauguccaau aauguccaaa uaguaagaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cucgccuaug uaguacaacu acccuuauac      900

ggaguaauug acacaccaug uuggaaacua cauacaucac cacuaugcac cacuaacaca      960

aaagaaggcu ccaacauaug ccuaacccga acagaucgcg gaugguauug cgacaacgca     1020

ggaaguguau ccuucuuucc acaagcagaa acaugcaaag uacaauccaa cagaguauuc     1080

ugugacacca ugaacucucu aacacuaccu uccgaaguaa auuuaugcaa cguagacaua     1140

uuuaauccca aauacgacug uaaaauaaug accucaaaaa cugaugucuc aucaucaguc     1200

auuacaucac ucggagcaau agucaguugc uauggaaaaa ccaaaugcac agcuaguaac     1260

aaaaacaggg guauaauaaa aacauuuuca aacggaugcg auuacguauc aaauaaagga     1320

guagacaccg uauccguagg aaauacucuc uacugcguaa acaaacaaga aggacaaucc     1380

cuauacguaa aaggcgaacc aaucauuaac uuuuacgacc cacuuguauu uccaucagac     1440

gaauuugaug ccucaauauc ccaagucaau gaaaaaauaa accaaagucu agcauucauc     1500

cgaaaaucag augaacuuuu acacaacgua aacgccggaa aaucaacaac aaacaucaug     1560

aucacaacaa ucaucauagu aauaauaguu auacuacuuu ccuuaauagc agucggccua     1620

cuacucuacu gcaaagcacg auccacacca guaaccuuau cuaaagacca acucucaggc     1680

auaaacaaca uagcauucuc aaacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3432
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3432
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gcaaacgcca ucacaaccau ccucacagca gucacuuucu gcuucgcauc cggacaaaac      180

aucacagaag aguucuauca auccacgugc uccgcaguuu ccaaaggaua ccuuggagcc      240

uuacgaaccg gcugguacac cuccgucauc accauagaac ucagcaacau caaagaaauc      300

aaaugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaccucca acuacucaug caaucaaccc ccgcaaccgg cuccggcucc      420

gccaucugcu ccggaguagc cguaugcaaa guccuccacc ucgaaggcga aguuaacaag      480

aucaaguccg cacuccuauc aaccaacaaa gcagucgucu cccuauccaa cggcgucucc      540

guauuaacau ucaaaguccu cgaccucaaa aacuacauag acaaacagcu acuccccauc      600

cuaaacaaac aauccugcuc cauccccaac aucgaaacug ucaucgaguu ccaacagaaa      660

aacaaccgcc uccuagaaau cacccgagag uucuccguaa acgccggcgu cacuaccccc      720

gucucuaccu auaugcuaac caacucugaa cuccuauccc uaaucaacga uaugcccaua      780

acuaacgacc aaaagaaacu uauguccaac aacguacaaa uaguccggca acaaucauac      840

ucuaucaugu gcaucaucaa agaagaagua cuugccuacg uuguccaacu cccacuauac      900

ggcgucauag acacuccaug cuggaaacuu cacaccucac cccucugcac cacuaacacu      960

aaagaaggcu cuaacaucug ccuuacccgc accgaccgcg gaugguacug cgacaacgca     1020

ggcucaguua gcuucuuccc acaagccgaa accugcaaag uccagucaaa ccgugucuuc     1080

ugcgauacca ugaacucgcu cacccucccu uccgaaguca accucugcaa cgucgacauc     1140

uucaacccca aauacgacug caaaaucaug accucaaaaa ccgacguauc uucuuccguc     1200

aucaccuccc ucggcgccau cguauccugc uacggcaaaa ccaaaugcac ugcaucaaac     1260

aaaaaccgag gcaucaucaa aaccuucucg aacggaugcg acuacguauc caacaagggc     1320

gucgacacag ucuccguugg uaacacccuc uacugcguca acaaacaaga aggccaaucc     1380

cuauacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagugac     1440

gaauuugacg ccuccaucuc ccaagucaac gaaaagauca accaaucccu ugccuucaua     1500

cgcaaauccg acgaacuccu acacaacguu aacgccggaa aaucaacaac caacaucaug     1560

aucacaacca ucauaaucgu cauaaucguc auacuccucu cccucauagc cgucggccug     1620

cuauuguacu guaaagcccg cuccacacca gucacacuuu caaaagacca acucuccggg     1680

aucaacaaca ucgccuucuc caacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3433
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3433
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3434
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3434
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3435
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3435
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3436
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3436
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggaucaa uaacauugca uucagcaauu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3437
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3437
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3438
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3438
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaaucaa uaacaucgcu uucagcaauu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3439
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3439
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac uaaaagccaa ugccauaacc acuauucuaa cagcaguaac auucuguuuc      240

gccucaggac aaaacauaac agaagaauuu uaucaaucca ccuguuccgc agucucgaaa      300

ggcuaccuug gcgcacuaag aaccggaugg uauacaucag uaauaaccau ugaacuauca      360

aauaucaaag aaauaaaaug caacggaacu gacgcaaaag ucaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc cguuacagac uuacaacuac uaaugcaauc aacuccagca      480

acaggaucag gaucugcuau augcucaggu gucgccguau guaaaguguu acaccucgaa      540

ggcgaaguaa acaaaauaaa aucagcacua cuauccacaa auaaagcagu aguaucacua      600

uccaauggug uaucaguacu cacauucaaa guacuagacu uaaaaaauua uauagauaaa      660

caauuacuac caauauuaaa caaacaauca ugcucaauac caaacauaga aaccgucauu      720

gaauuucaac aaaaaaacaa ucgacuucuu gaaauaacac gagaauuuuc aguaaaugcc      780

ggaguaacaa ccccagucuc aacauacaug uuaaccaacu cugaacuccu aagccuaauc      840

aacgacaugc ccauaacuaa cgaccaaaaa aaacuaaugu ccaauaaugu ccaaauagua      900

agacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccucgc cuauguagua      960

caacuacccu uauacggagu aauugacaca ccauguugga aacuacauac aucaccacua     1020

ugcaccacua acacaaaaga aggcuccaac auaugccuaa cccgaacaga ucgcggaugg     1080

uauugcgaca acgcaggaag uguauccuuc uuuccacaag cagaaacaug caaaguacaa     1140

uccaacagag uauucuguga caccaugaac ucucuaacac uaccuuccga aguaaauuua     1200

ugcaacguag acauauuuaa ucccaaauac gacuguaaaa uaaugaccuc aaaaacugau     1260

gucucaucau cagucauuac aucacucgga gcaauaguca guugcuaugg aaaaaccaaa     1320

ugcacagcua guaacaaaaa cagggguaua auaaaaacau uuucaaacgg augcgauuac     1380

guaucaaaua aaggaguaga caccguaucc guaggaaaua cucucuacug cguaaacaaa     1440

caagaaggac aaucccuaua cguaaaaggc gaaccaauca uuaacuuuua cgacccacuu     1500

guauuuccau cagacgaauu ugaugccuca auaucccaag ucaaugaaaa aauaaaccaa     1560

agucuagcau ucauccgaaa aucagaugaa cuuuuacaca acguaaacgc cggaaaauca     1620

acaacaaaca ucaugaucac aacaaucauc auaguaauaa uaguuauacu acuuuccuua     1680

auagcagucg gccuacuacu cuacugcaaa gcacgaucca caccaguaac cuuaucuaaa     1740

gaccaacucu caggcauaaa caacauagca uucucaaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3440
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3440
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagcaaa cgccaucaca accauccuca cagcagucac uuucugcuuc      240

gcauccggac aaaacaucac agaagaguuc uaucaaucca cgugcuccgc aguuuccaaa      300

ggauaccuug gagccuuacg aaccggcugg uacaccuccg ucaucaccau agaacucagc      360

aacaucaaag aaaucaaaug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaacgc agucaccgac cuccaacuac ucaugcaauc aacccccgca      480

accggcuccg gcuccgccau cugcuccgga guagccguau gcaaaguccu ccaccucgaa      540

ggcgaaguua acaagaucaa guccgcacuc cuaucaacca acaaagcagu cgucucccua      600

uccaacggcg ucuccguauu aacauucaaa guccucgacc ucaaaaacua cauagacaaa      660

cagcuacucc ccauccuaaa caaacaaucc ugcuccaucc ccaacaucga aacugucauc      720

gaguuccaac agaaaaacaa ccgccuccua gaaaucaccc gagaguucuc cguaaacgcc      780

ggcgucacua cccccgucuc uaccuauaug cuaaccaacu cugaacuccu aucccuaauc      840

aacgauaugc ccauaacuaa cgaccaaaag aaacuuaugu ccaacaacgu acaaauaguc      900

cggcaacaau cauacucuau caugugcauc aucaaagaag aaguacuugc cuacguuguc      960

caacucccac uauacggcgu cauagacacu ccaugcugga aacuucacac cucaccccuc     1020

ugcaccacua acacuaaaga aggcucuaac aucugccuua cccgcaccga ccgcggaugg     1080

uacugcgaca acgcaggcuc aguuagcuuc uucccacaag ccgaaaccug caaaguccag     1140

ucaaaccgug ucuucugcga uaccaugaac ucgcucaccc ucccuuccga agucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

guaucuucuu ccgucaucac cucccucggc gccaucguau ccugcuacgg caaaaccaaa     1320

ugcacugcau caaacaaaaa ccgaggcauc aucaaaaccu ucucgaacgg augcgacuac     1380

guauccaaca agggcgucga cacagucucc guugguaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccuaua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuucccca gugacgaauu ugacgccucc aucucccaag ucaacgaaaa gaucaaccaa     1560

ucccuugccu ucauacgcaa auccgacgaa cuccuacaca acguuaacgc cggaaaauca     1620

acaaccaaca ucaugaucac aaccaucaua aucgucauaa ucgucauacu ccucucccuc     1680

auagccgucg gccugcuauu guacuguaaa gcccgcucca caccagucac acuuucaaaa     1740

gaccaacucu ccgggaucaa caacaucgcc uucuccaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  3441
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3441
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3442
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3442
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3443
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3443
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3444
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3444
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggaucaa uaacauugca uucagcaauu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3445
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3445
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3446
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3446
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaaucaa uaacaucgcu uucagcaauu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3447
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3447
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac uaaaagccaa ugccauaacc acuauucuaa cagcaguaac auucuguuuc      240

gccucaggac aaaacauaac agaagaauuu uaucaaucca ccuguuccgc agucucgaaa      300

ggcuaccuug gcgcacuaag aaccggaugg uauacaucag uaauaaccau ugaacuauca      360

aauaucaaag aaauaaaaug caacggaacu gacgcaaaag ucaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc cguuacagac uuacaacuac uaaugcaauc aacuccagca      480

acaggaucag gaucugcuau augcucaggu gucgccguau guaaaguguu acaccucgaa      540

ggcgaaguaa acaaaauaaa aucagcacua cuauccacaa auaaagcagu aguaucacua      600

uccaauggug uaucaguacu cacauucaaa guacuagacu uaaaaaauua uauagauaaa      660

caauuacuac caauauuaaa caaacaauca ugcucaauac caaacauaga aaccgucauu      720

gaauuucaac aaaaaaacaa ucgacuucuu gaaauaacac gagaauuuuc aguaaaugcc      780

ggaguaacaa ccccagucuc aacauacaug uuaaccaacu cugaacuccu aagccuaauc      840

aacgacaugc ccauaacuaa cgaccaaaaa aaacuaaugu ccaauaaugu ccaaauagua      900

agacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccucgc cuauguagua      960

caacuacccu uauacggagu aauugacaca ccauguugga aacuacauac aucaccacua     1020

ugcaccacua acacaaaaga aggcuccaac auaugccuaa cccgaacaga ucgcggaugg     1080

uauugcgaca acgcaggaag uguauccuuc uuuccacaag cagaaacaug caaaguacaa     1140

uccaacagag uauucuguga caccaugaac ucucuaacac uaccuuccga aguaaauuua     1200

ugcaacguag acauauuuaa ucccaaauac gacuguaaaa uaaugaccuc aaaaacugau     1260

gucucaucau cagucauuac aucacucgga gcaauaguca guugcuaugg aaaaaccaaa     1320

ugcacagcua guaacaaaaa cagggguaua auaaaaacau uuucaaacgg augcgauuac     1380

guaucaaaua aaggaguaga caccguaucc guaggaaaua cucucuacug cguaaacaaa     1440

caagaaggac aaucccuaua cguaaaaggc gaaccaauca uuaacuuuua cgacccacuu     1500

guauuuccau cagacgaauu ugaugccuca auaucccaag ucaaugaaaa aauaaaccaa     1560

agucuagcau ucauccgaaa aucagaugaa cuuuuacaca acguaaacgc cggaaaauca     1620

acaacaaaca ucaugaucac aacaaucauc auaguaauaa uaguuauacu acuuuccuua     1680

auagcagucg gccuacuacu cuacugcaaa gcacgaucca caccaguaac cuuaucuaaa     1740

gaccaacucu caggcauaaa caacauagca uucucaaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3448
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3448
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagcaaa cgccaucaca accauccuca cagcagucac uuucugcuuc      240

gcauccggac aaaacaucac agaagaguuc uaucaaucca cgugcuccgc aguuuccaaa      300

ggauaccuug gagccuuacg aaccggcugg uacaccuccg ucaucaccau agaacucagc      360

aacaucaaag aaaucaaaug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaacgc agucaccgac cuccaacuac ucaugcaauc aacccccgca      480

accggcuccg gcuccgccau cugcuccgga guagccguau gcaaaguccu ccaccucgaa      540

ggcgaaguua acaagaucaa guccgcacuc cuaucaacca acaaagcagu cgucucccua      600

uccaacggcg ucuccguauu aacauucaaa guccucgacc ucaaaaacua cauagacaaa      660

cagcuacucc ccauccuaaa caaacaaucc ugcuccaucc ccaacaucga aacugucauc      720

gaguuccaac agaaaaacaa ccgccuccua gaaaucaccc gagaguucuc cguaaacgcc      780

ggcgucacua cccccgucuc uaccuauaug cuaaccaacu cugaacuccu aucccuaauc      840

aacgauaugc ccauaacuaa cgaccaaaag aaacuuaugu ccaacaacgu acaaauaguc      900

cggcaacaau cauacucuau caugugcauc aucaaagaag aaguacuugc cuacguuguc      960

caacucccac uauacggcgu cauagacacu ccaugcugga aacuucacac cucaccccuc     1020

ugcaccacua acacuaaaga aggcucuaac aucugccuua cccgcaccga ccgcggaugg     1080

uacugcgaca acgcaggcuc aguuagcuuc uucccacaag ccgaaaccug caaaguccag     1140

ucaaaccgug ucuucugcga uaccaugaac ucgcucaccc ucccuuccga agucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

guaucuucuu ccgucaucac cucccucggc gccaucguau ccugcuacgg caaaaccaaa     1320

ugcacugcau caaacaaaaa ccgaggcauc aucaaaaccu ucucgaacgg augcgacuac     1380

guauccaaca agggcgucga cacagucucc guugguaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccuaua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuucccca gugacgaauu ugacgccucc aucucccaag ucaacgaaaa gaucaaccaa     1560

ucccuugccu ucauacgcaa auccgacgaa cuccuacaca acguuaacgc cggaaaauca     1620

acaaccaaca ucaugaucac aaccaucaua aucgucauaa ucgucauacu ccucucccuc     1680

auagccgucg gccugcuauu guacuguaaa gcccgcucca caccagucac acuuucaaaa     1740

gaccaacucu ccgggaucaa caacaucgcc uucuccaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  3449
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3449
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3450
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3450
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggucca cccccgugac ccugagcaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3451
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3451
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3452
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3452
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcucaa cacccgugac ccugaguaaa     1740

gaucaacucu cugggaucaa uaacauugca uucagcaauu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3453
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3453
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3454
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3454
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaagca cacccgugac ccuuucuaaa     1740

gaucaacucu ccggaaucaa uaacaucgcu uucagcaauu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3455
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3455
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac uaaaagccaa ugccauaacc acuauucuaa cagcaguaac auucuguuuc      240

gccucaggac aaaacauaac agaagaauuu uaucaaucca ccuguuccgc agucucgaaa      300

ggcuaccuug gcgcacuaag aaccggaugg uauacaucag uaauaaccau ugaacuauca      360

aauaucaaag aaauaaaaug caacggaacu gacgcaaaag ucaaacuaau aaaacaagaa      420

uuagacaaau acaaaaacgc cguuacagac uuacaacuac uaaugcaauc aacuccagca      480

acaggaucag gaucugcuau augcucaggu gucgccguau guaaaguguu acaccucgaa      540

ggcgaaguaa acaaaauaaa aucagcacua cuauccacaa auaaagcagu aguaucacua      600

uccaauggug uaucaguacu cacauucaaa guacuagacu uaaaaaauua uauagauaaa      660

caauuacuac caauauuaaa caaacaauca ugcucaauac caaacauaga aaccgucauu      720

gaauuucaac aaaaaaacaa ucgacuucuu gaaauaacac gagaauuuuc aguaaaugcc      780

ggaguaacaa ccccagucuc aacauacaug uuaaccaacu cugaacuccu aagccuaauc      840

aacgacaugc ccauaacuaa cgaccaaaaa aaacuaaugu ccaauaaugu ccaaauagua      900

agacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccucgc cuauguagua      960

caacuacccu uauacggagu aauugacaca ccauguugga aacuacauac aucaccacua     1020

ugcaccacua acacaaaaga aggcuccaac auaugccuaa cccgaacaga ucgcggaugg     1080

uauugcgaca acgcaggaag uguauccuuc uuuccacaag cagaaacaug caaaguacaa     1140

uccaacagag uauucuguga caccaugaac ucucuaacac uaccuuccga aguaaauuua     1200

ugcaacguag acauauuuaa ucccaaauac gacuguaaaa uaaugaccuc aaaaacugau     1260

gucucaucau cagucauuac aucacucgga gcaauaguca guugcuaugg aaaaaccaaa     1320

ugcacagcua guaacaaaaa cagggguaua auaaaaacau uuucaaacgg augcgauuac     1380

guaucaaaua aaggaguaga caccguaucc guaggaaaua cucucuacug cguaaacaaa     1440

caagaaggac aaucccuaua cguaaaaggc gaaccaauca uuaacuuuua cgacccacuu     1500

guauuuccau cagacgaauu ugaugccuca auaucccaag ucaaugaaaa aauaaaccaa     1560

agucuagcau ucauccgaaa aucagaugaa cuuuuacaca acguaaacgc cggaaaauca     1620

acaacaaaca ucaugaucac aacaaucauc auaguaauaa uaguuauacu acuuuccuua     1680

auagcagucg gccuacuacu cuacugcaaa gcacgaucca caccaguaac cuuaucuaaa     1740

gaccaacucu caggcauaaa caacauagca uucucaaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3456
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3456
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagcaaa cgccaucaca accauccuca cagcagucac uuucugcuuc      240

gcauccggac aaaacaucac agaagaguuc uaucaaucca cgugcuccgc aguuuccaaa      300

ggauaccuug gagccuuacg aaccggcugg uacaccuccg ucaucaccau agaacucagc      360

aacaucaaag aaaucaaaug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaaaaacgc agucaccgac cuccaacuac ucaugcaauc aacccccgca      480

accggcuccg gcuccgccau cugcuccgga guagccguau gcaaaguccu ccaccucgaa      540

ggcgaaguua acaagaucaa guccgcacuc cuaucaacca acaaagcagu cgucucccua      600

uccaacggcg ucuccguauu aacauucaaa guccucgacc ucaaaaacua cauagacaaa      660

cagcuacucc ccauccuaaa caaacaaucc ugcuccaucc ccaacaucga aacugucauc      720

gaguuccaac agaaaaacaa ccgccuccua gaaaucaccc gagaguucuc cguaaacgcc      780

ggcgucacua cccccgucuc uaccuauaug cuaaccaacu cugaacuccu aucccuaauc      840

aacgauaugc ccauaacuaa cgaccaaaag aaacuuaugu ccaacaacgu acaaauaguc      900

cggcaacaau cauacucuau caugugcauc aucaaagaag aaguacuugc cuacguuguc      960

caacucccac uauacggcgu cauagacacu ccaugcugga aacuucacac cucaccccuc     1020

ugcaccacua acacuaaaga aggcucuaac aucugccuua cccgcaccga ccgcggaugg     1080

uacugcgaca acgcaggcuc aguuagcuuc uucccacaag ccgaaaccug caaaguccag     1140

ucaaaccgug ucuucugcga uaccaugaac ucgcucaccc ucccuuccga agucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

guaucuucuu ccgucaucac cucccucggc gccaucguau ccugcuacgg caaaaccaaa     1320

ugcacugcau caaacaaaaa ccgaggcauc aucaaaaccu ucucgaacgg augcgacuac     1380

guauccaaca agggcgucga cacagucucc guugguaaca cccucuacug cgucaacaaa     1440

caagaaggcc aaucccuaua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuucccca gugacgaauu ugacgccucc aucucccaag ucaacgaaaa gaucaaccaa     1560

ucccuugccu ucauacgcaa auccgacgaa cuccuacaca acguuaacgc cggaaaauca     1620

acaaccaaca ucaugaucac aaccaucaua aucgucauaa ucgucauacu ccucucccuc     1680

auagccgucg gccugcuauu guacuguaaa gcccgcucca caccagucac acuuucaaaa     1740

gaccaacucu ccgggaucaa caacaucgcc uucuccaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3457
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3457
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3458
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3458
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1620

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3459
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3459
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3460
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3460
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      480

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      540

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      600

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      660

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      720

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      780

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg      960

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1260

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1440

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1500

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1560

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu caacacccgu gacccugagu     1620

aaagaucaac ucucugggau caauaacauu gcauucagca auugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3461
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3461
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3462
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3462
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      480

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      540

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      600

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      660

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      720

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      780

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc      960

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1140

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1260

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1440

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1500

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1560

cugauugccg uggggcuccu gcuguauugc aaggccagaa gcacacccgu gacccuuucu     1620

aaagaucaac ucuccggaau caauaacauc gcuuucagca auugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3463
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3463
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaauuacuca uacuaaaagc caaugccaua accacuauuc uaacagcagu aacauucugu      120

uucgccucag gacaaaacau aacagaagaa uuuuaucaau ccaccuguuc cgcagucucg      180

aaaggcuacc uuggcgcacu aagaaccgga ugguauacau caguaauaac cauugaacua      240

ucaaauauca aagaaauaaa augcaacgga acugacgcaa aagucaaacu aauaaaacaa      300

gaauuagaca aauacaaaaa cgccguuaca gacuuacaac uacuaaugca aucaacucca      360

gcaacaggau caggaucugc uauaugcuca ggugucgccg uauguaaagu guuacaccuc      420

gaaggcgaag uaaacaaaau aaaaucagca cuacuaucca caaauaaagc aguaguauca      480

cuauccaaug guguaucagu acucacauuc aaaguacuag acuuaaaaaa uuauauagau      540

aaacaauuac uaccaauauu aaacaaacaa ucaugcucaa uaccaaacau agaaaccguc      600

auugaauuuc aacaaaaaaa caaucgacuu cuugaaauaa cacgagaauu uucaguaaau      660

gccggaguaa caaccccagu cucaacauac auguuaacca acucugaacu ccuaagccua      720

aucaacgaca ugcccauaac uaacgaccaa aaaaaacuaa uguccaauaa uguccaaaua      780

guaagacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu cgccuaugua      840

guacaacuac ccuuauacgg aguaauugac acaccauguu ggaaacuaca uacaucacca      900

cuaugcacca cuaacacaaa agaaggcucc aacauaugcc uaacccgaac agaucgcgga      960

ugguauugcg acaacgcagg aaguguaucc uucuuuccac aagcagaaac augcaaagua     1020

caauccaaca gaguauucug ugacaccaug aacucucuaa cacuaccuuc cgaaguaaau     1080

uuaugcaacg uagacauauu uaaucccaaa uacgacugua aaauaaugac cucaaaaacu     1140

gaugucucau caucagucau uacaucacuc ggagcaauag ucaguugcua uggaaaaacc     1200

aaaugcacag cuaguaacaa aaacaggggu auaauaaaaa cauuuucaaa cggaugcgau     1260

uacguaucaa auaaaggagu agacaccgua uccguaggaa auacucucua cugcguaaac     1320

aaacaagaag gacaaucccu auacguaaaa ggcgaaccaa ucauuaacuu uuacgaccca     1380

cuuguauuuc caucagacga auuugaugcc ucaauauccc aagucaauga aaaaauaaac     1440

caaagucuag cauucauccg aaaaucagau gaacuuuuac acaacguaaa cgccggaaaa     1500

ucaacaacaa acaucaugau cacaacaauc aucauaguaa uaauaguuau acuacuuucc     1560

uuaauagcag ucggccuacu acucuacugc aaagcacgau ccacaccagu aaccuuaucu     1620

aaagaccaac ucucaggcau aaacaacaua gcauucucaa acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3464
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3464
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccuuaaagc aaacgccauc acaaccaucc ucacagcagu cacuuucugc      120

uucgcauccg gacaaaacau cacagaagag uucuaucaau ccacgugcuc cgcaguuucc      180

aaaggauacc uuggagccuu acgaaccggc ugguacaccu ccgucaucac cauagaacuc      240

agcaacauca aagaaaucaa augcaacgga accgacgcaa aagucaaacu caucaaacaa      300

gaacuagaca aauacaaaaa cgcagucacc gaccuccaac uacucaugca aucaaccccc      360

gcaaccggcu ccggcuccgc caucugcucc ggaguagccg uaugcaaagu ccuccaccuc      420

gaaggcgaag uuaacaagau caaguccgca cuccuaucaa ccaacaaagc agucgucucc      480

cuauccaacg gcgucuccgu auuaacauuc aaaguccucg accucaaaaa cuacauagac      540

aaacagcuac uccccauccu aaacaaacaa uccugcucca uccccaacau cgaaacuguc      600

aucgaguucc aacagaaaaa caaccgccuc cuagaaauca cccgagaguu cuccguaaac      660

gccggcguca cuacccccgu cucuaccuau augcuaacca acucugaacu ccuaucccua      720

aucaacgaua ugcccauaac uaacgaccaa aagaaacuua uguccaacaa cguacaaaua      780

guccggcaac aaucauacuc uaucaugugc aucaucaaag aagaaguacu ugccuacguu      840

guccaacucc cacuauacgg cgucauagac acuccaugcu ggaaacuuca caccucaccc      900

cucugcacca cuaacacuaa agaaggcucu aacaucugcc uuacccgcac cgaccgcgga      960

ugguacugcg acaacgcagg cucaguuagc uucuucccac aagccgaaac cugcaaaguc     1020

cagucaaacc gugucuucug cgauaccaug aacucgcuca cccucccuuc cgaagucaac     1080

cucugcaacg ucgacaucuu caaccccaaa uacgacugca aaaucaugac cucaaaaacc     1140

gacguaucuu cuuccgucau caccucccuc ggcgccaucg uauccugcua cggcaaaacc     1200

aaaugcacug caucaaacaa aaaccgaggc aucaucaaaa ccuucucgaa cggaugcgac     1260

uacguaucca acaagggcgu cgacacaguc uccguuggua acacccucua cugcgucaac     1320

aaacaagaag gccaaucccu auacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccagugacga auuugacgcc uccaucuccc aagucaacga aaagaucaac     1440

caaucccuug ccuucauacg caaauccgac gaacuccuac acaacguuaa cgccggaaaa     1500

ucaacaacca acaucaugau cacaaccauc auaaucguca uaaucgucau acuccucucc     1560

cucauagccg ucggccugcu auuguacugu aaagcccgcu ccacaccagu cacacuuuca     1620

aaagaccaac ucuccgggau caacaacauc gccuucucca acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3465
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3465
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc cuguccaagg     1620

accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3466
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3466
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug gucagccucu      480

ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug agccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac cggggcuggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag gucaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc gucaacaagc     1320

aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac gacccccugg     1380

uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg gcuccugcug uacugcaagg cccgguccac ccccgugacc cugagcaagg     1620

accagcucuc cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3467
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3467
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc cucuccaagg     1620

accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3468
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3468
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua aagcaggaac      300

ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug caccucgagg      420

gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug gucucccucu      480

cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac aucgacaaac      540

aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa accgugauug      600

aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu gucaaugccg      660

gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug ucccucauua      720

augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc cagaucguuc      780

gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg uauguagugc      840

aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca ucuccccugu      900

gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac cguggguggu      960

acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu aagguucagu     1020

cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa gucaaucucu     1080

gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu aaaacagaug     1140

uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc aagaccaaau     1200

guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga ugcgacuaug     1260

ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu guuaauaagc     1320

aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac gauccauugg     1380

uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag auuaaucagu     1440

cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc ggcaagagca     1500

caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug cuaucccuca     1560

uagcggucgg ccugcuuuug uauugcaagg cccgcucaac acccgugacc cugaguaaag     1620

aucaacucuc ugggaucaau aacauugcau ucagcaauug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3469
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3469
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc cugagcaagg     1620

accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3470
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3470
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu aagcaggaac      300

uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc caccuggagg      420

gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc gugucucucu      480

ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac aucgacaaac      540

aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa accgugaucg      600

aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc gugaaugcug      660

gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc agccugauua      720

augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug cagauuguga      780

gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc uaugugguuc      840

aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg agcccccucu      900

gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac cgcggcuggu      960

acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu aaggugcaga     1020

gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa gugaaucucu     1080

gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc aaaacagaug     1140

ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc aagacaaaau     1200

guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga ugcgacuaug     1260

uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu guuaauaagc     1320

aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac gauccccucg     1380

ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag aucaaucagu     1440

cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu ggcaagagca     1500

caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug cuuucccuga     1560

uugccguggg gcuccugcug uauugcaagg ccagaagcac acccgugacc cuuucuaaag     1620

aucaacucuc cggaaucaau aacaucgcuu ucagcaauug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3471
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3471
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaau       60

uacucauacu aaaagccaau gccauaacca cuauucuaac agcaguaaca uucuguuucg      120

ccucaggaca aaacauaaca gaagaauuuu aucaauccac cuguuccgca gucucgaaag      180

gcuaccuugg cgcacuaaga accggauggu auacaucagu aauaaccauu gaacuaucaa      240

auaucaaaga aauaaaaugc aacggaacug acgcaaaagu caaacuaaua aaacaagaau      300

uagacaaaua caaaaacgcc guuacagacu uacaacuacu aaugcaauca acuccagcaa      360

caggaucagg aucugcuaua ugcucaggug ucgccguaug uaaaguguua caccucgaag      420

gcgaaguaaa caaaauaaaa ucagcacuac uauccacaaa uaaagcagua guaucacuau      480

ccaauggugu aucaguacuc acauucaaag uacuagacuu aaaaaauuau auagauaaac      540

aauuacuacc aauauuaaac aaacaaucau gcucaauacc aaacauagaa accgucauug      600

aauuucaaca aaaaaacaau cgacuucuug aaauaacacg agaauuuuca guaaaugccg      660

gaguaacaac cccagucuca acauacaugu uaaccaacuc ugaacuccua agccuaauca      720

acgacaugcc cauaacuaac gaccaaaaaa aacuaauguc caauaauguc caaauaguaa      780

gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccucgcc uauguaguac      840

aacuacccuu auacggagua auugacacac cauguuggaa acuacauaca ucaccacuau      900

gcaccacuaa cacaaaagaa ggcuccaaca uaugccuaac ccgaacagau cgcggauggu      960

auugcgacaa cgcaggaagu guauccuucu uuccacaagc agaaacaugc aaaguacaau     1020

ccaacagagu auucugugac accaugaacu cucuaacacu accuuccgaa guaaauuuau     1080

gcaacguaga cauauuuaau cccaaauacg acuguaaaau aaugaccuca aaaacugaug     1140

ucucaucauc agucauuaca ucacucggag caauagucag uugcuaugga aaaaccaaau     1200

gcacagcuag uaacaaaaac agggguauaa uaaaaacauu uucaaacgga ugcgauuacg     1260

uaucaaauaa aggaguagac accguauccg uaggaaauac ucucuacugc guaaacaaac     1320

aagaaggaca aucccuauac guaaaaggcg aaccaaucau uaacuuuuac gacccacuug     1380

uauuuccauc agacgaauuu gaugccucaa uaucccaagu caaugaaaaa auaaaccaaa     1440

gucuagcauu cauccgaaaa ucagaugaac uuuuacacaa cguaaacgcc ggaaaaucaa     1500

caacaaacau caugaucaca acaaucauca uaguaauaau aguuauacua cuuuccuuaa     1560

uagcagucgg ccuacuacuc uacugcaaag cacgauccac accaguaacc uuaucuaaag     1620

accaacucuc aggcauaaac aacauagcau ucucaaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3472
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3472
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu uaaagcaaac gccaucacaa ccauccucac agcagucacu uucugcuucg      120

cauccggaca aaacaucaca gaagaguucu aucaauccac gugcuccgca guuuccaaag      180

gauaccuugg agccuuacga accggcuggu acaccuccgu caucaccaua gaacucagca      240

acaucaaaga aaucaaaugc aacggaaccg acgcaaaagu caaacucauc aaacaagaac      300

uagacaaaua caaaaacgca gucaccgacc uccaacuacu caugcaauca acccccgcaa      360

ccggcuccgg cuccgccauc ugcuccggag uagccguaug caaaguccuc caccucgaag      420

gcgaaguuaa caagaucaag uccgcacucc uaucaaccaa caaagcaguc gucucccuau      480

ccaacggcgu cuccguauua acauucaaag uccucgaccu caaaaacuac auagacaaac      540

agcuacuccc cauccuaaac aaacaauccu gcuccauccc caacaucgaa acugucaucg      600

aguuccaaca gaaaaacaac cgccuccuag aaaucacccg agaguucucc guaaacgccg      660

gcgucacuac ccccgucucu accuauaugc uaaccaacuc ugaacuccua ucccuaauca      720

acgauaugcc cauaacuaac gaccaaaaga aacuuauguc caacaacgua caaauagucc      780

ggcaacaauc auacucuauc augugcauca ucaaagaaga aguacuugcc uacguugucc      840

aacucccacu auacggcguc auagacacuc caugcuggaa acuucacacc ucaccccucu      900

gcaccacuaa cacuaaagaa ggcucuaaca ucugccuuac ccgcaccgac cgcggauggu      960

acugcgacaa cgcaggcuca guuagcuucu ucccacaagc cgaaaccugc aaaguccagu     1020

caaaccgugu cuucugcgau accaugaacu cgcucacccu cccuuccgaa gucaaccucu     1080

gcaacgucga caucuucaac cccaaauacg acugcaaaau caugaccuca aaaaccgacg     1140

uaucuucuuc cgucaucacc ucccucggcg ccaucguauc cugcuacggc aaaaccaaau     1200

gcacugcauc aaacaaaaac cgaggcauca ucaaaaccuu cucgaacgga ugcgacuacg     1260

uauccaacaa gggcgucgac acagucuccg uugguaacac ccucuacugc gucaacaaac     1320

aagaaggcca aucccuauac guaaaaggcg aacccaucau caacuucuac gacccccucg     1380

ucuuccccag ugacgaauuu gacgccucca ucucccaagu caacgaaaag aucaaccaau     1440

cccuugccuu cauacgcaaa uccgacgaac uccuacacaa cguuaacgcc ggaaaaucaa     1500

caaccaacau caugaucaca accaucauaa ucgucauaau cgucauacuc cucucccuca     1560

uagccgucgg ccugcuauug uacuguaaag cccgcuccac accagucaca cuuucaaaag     1620

accaacucuc cgggaucaac aacaucgccu ucuccaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  3473
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1) R6770

<400>  3473
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccggagc     1560

acgcccguca cccuguccaa ggaccagcug agcggcauca acaacaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3474
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt1)

<400>  3474
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucugcuccgg cguggccgug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcgcu gcuguccacc      420

aacaaggccg uggucagccu cuccaacggc gugagcgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcaguc cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcucaccaac      660

uccgagcugc ugagccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccg cuguacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggguccaa caucugccug      900

acccgcaccg accggggcug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cucccguccg aggucaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccucuacu gcgucaacaa gcaggagggc cagagccugu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccccu gguguucccg agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cgggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug gggcuccugc uguacugcaa ggcccggucc     1560

acccccguga cccugagcaa ggaccagcuc uccggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3475
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt2)

<400>  3475
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcucc     1560

acccccguca cccucuccaa ggaccagcuc uccggcauca acaacaucgc cuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3476
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt3)

<400>  3476
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaucaaau gcaauggcac cgacgccaag      240

gugaaacuaa uaaagcagga acucgauaag uauaaaaacg caguaacuga ccugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua ucuguucagg cguggcaguc      360

ugcaaggugu ugcaccucga gggugagguu aauaaaauua agagcgcccu gcugaguacg      420

aacaaagcug uggucucccu cucuaauggg gugagcguau uaacuuuuaa gguucuggau      480

cuuaagaacu acaucgacaa acaauugcug ccuauucuaa auaagcaguc cuguucaauc      540

ccaaacauag aaaccgugau ugaguuccag cagaaaaaua acaggcuccu ggaaaucaca      600

cgggaguuua gugucaaugc cggagugacu accccgguga gcacauauau gcuuaccaac      660

ucugagcugu ugucccucau uaaugauaug cccaucacga acgaccaaaa gaaacugaug      720

ucaaacaaug uccagaucgu ucgccagcag agcuacagua uuaugugcau aaucaaggaa      780

gagguguuag cguauguagu gcaacugccu cucuacggcg ucauugauac uccauguugg      840

aaacuucaua caucuccccu gugcaccacu aacacaaagg aaggcuccaa uaucuguuug      900

acccgaacgg accgugggug guacugcgau aacgcaggaa gcgugucguu cuuuccucag      960

gccgagaccu guaagguuca gucuaauaga guguucugcg acacaaugaa cucccuaacu     1020

cugccaucag aagucaaucu cugcaacgug gauauauuua aucccaaaua ugacuguaag     1080

auuaugacca guaaaacaga uguaagcucc ucuguuauca cuagccuggg ugcuaucgug     1140

ucaugcuacg gcaagaccaa auguacagcc aguaacaaga auagggggau uaucaagacc     1200

uucuccaacg gaugcgacua ugucagcaau aaaggcgugg acacugucuc uguggguaac     1260

acgcuuuacu guguuaauaa gcaagagggg cagucacugu augugaaagg agagccuauu     1320

auaaacuuuu acgauccauu gguauucccg agugacgaau uugaugcaag caucucccag     1380

gucaacgaga agauuaauca gucucucgcu uucauccgga aaucggacga acuguuacac     1440

aacgugaaug ccggcaagag cacaaccaac aucaugauua cuaccauaau cauuguuauc     1500

auugugaucc ugcuaucccu cauagcgguc ggccugcuuu uguauugcaa ggcccgcuca     1560

acacccguga cccugaguaa agaucaacuc ucugggauca auaacauugc auucagcaau     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3477
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt4)

<400>  3477
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagaagc     1560

acccccguga cccugagcaa ggaccagcug agcggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3478
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt5)

<400>  3478
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaucaaau gcaaugggac cgacgccaag      240

gugaaacuua uuaagcagga acuggauaag uauaaaaacg cugugacgga ccuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua ucuguagcgg ggucgccgug      360

ugcaagguuc uccaccugga gggagaggug aauaaaauua aguccgcgcu ucugagcacc      420

aacaaagccg ucgugucucu cuccaauggc guuagcgugc ugacauuuaa gguccuugau      480

cugaagaacu acaucgacaa acaacuccug ccuauucuga auaagcaguc uuguuccauc      540

ccgaacauug aaaccgugau cgaguuccag cagaaaaaua accggcuccu ggaaaucacg      600

cgcgaguuua gcgugaaugc uggcgucaca acccccguuu cuacauauau gcuuaccaac      660

uccgagcugc ucagccugau uaaugauaug ccuaucacca acgaccaaaa gaaacuuaug      720

uccaacaaug ugcagauugu gagacagcag ucuuacagca ucaugugcau uaucaaggaa      780

gagguccugg ccuauguggu ucaacucccc cuguacgggg ugaucgauac accuuguugg      840

aaacugcaua cgagcccccu cugcaccaca aacaccaagg aaggauccaa uauuugucug      900

acacggaccg accgcggcug guacugcgau aacgcugggu cugucuccuu cuuuccucag      960

gccgagacgu guaaggugca gagcaauaga guuuucugcg acacaaugaa cucucuuacc     1020

cugccgagcg aagugaaucu cugcaacguc gauaucuuua aucccaaaua ugacuguaag     1080

auuaugaccu ccaaaacaga ugugucuagc uccgucauca ccagccuggg agcgauugug     1140

ucuugcuacg gcaagacaaa auguacggcc uccaacaaga aucgggggau caucaagacc     1200

uucagcaacg gaugcgacua uguuucuaau aaaggcgugg acacagucuc cgugggcaac     1260

acccuuuacu guguuaauaa gcaagagggg cagagccugu augugaaagg agagccuauu     1320

aucaacuuuu acgauccccu cgucuucccu uccgacgaau uugaugcuuc uauuagccag     1380

gugaacgaga agaucaauca gucccuggcc uucauucgca aaucugacga acugcuccac     1440

aacgugaaug cuggcaagag cacaaccaac aucaugauua cgaccaucau cauuguuauc     1500

auugucaucc ugcuuucccu gauugccgug gggcuccugc uguauugcaa ggccagaagc     1560

acacccguga cccuuucuaa agaucaacuc uccggaauca auaacaucgc uuucagcaau     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3479
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt6)

<400>  3479
gggagaaagc uuaccaugga auuacucaua cuaaaagcca augccauaac cacuauucua       60

acagcaguaa cauucuguuu cgccucagga caaaacauaa cagaagaauu uuaucaaucc      120

accuguuccg cagucucgaa aggcuaccuu ggcgcacuaa gaaccggaug guauacauca      180

guaauaacca uugaacuauc aaauaucaaa gaaauaaaau gcaacggaac ugacgcaaaa      240

gucaaacuaa uaaaacaaga auuagacaaa uacaaaaacg ccguuacaga cuuacaacua      300

cuaaugcaau caacuccagc aacaggauca ggaucugcua uaugcucagg ugucgccgua      360

uguaaagugu uacaccucga aggcgaagua aacaaaauaa aaucagcacu acuauccaca      420

aauaaagcag uaguaucacu auccaauggu guaucaguac ucacauucaa aguacuagac      480

uuaaaaaauu auauagauaa acaauuacua ccaauauuaa acaaacaauc augcucaaua      540

ccaaacauag aaaccgucau ugaauuucaa caaaaaaaca aucgacuucu ugaaauaaca      600

cgagaauuuu caguaaaugc cggaguaaca accccagucu caacauacau guuaaccaac      660

ucugaacucc uaagccuaau caacgacaug cccauaacua acgaccaaaa aaaacuaaug      720

uccaauaaug uccaaauagu aagacaacaa uccuacucaa uaaugugcau uauaaaagaa      780

gaaguccucg ccuauguagu acaacuaccc uuauacggag uaauugacac accauguugg      840

aaacuacaua caucaccacu augcaccacu aacacaaaag aaggcuccaa cauaugccua      900

acccgaacag aucgcggaug guauugcgac aacgcaggaa guguauccuu cuuuccacaa      960

gcagaaacau gcaaaguaca auccaacaga guauucugug acaccaugaa cucucuaaca     1020

cuaccuuccg aaguaaauuu augcaacgua gacauauuua aucccaaaua cgacuguaaa     1080

auaaugaccu caaaaacuga ugucucauca ucagucauua caucacucgg agcaauaguc     1140

aguugcuaug gaaaaaccaa augcacagcu aguaacaaaa acagggguau aauaaaaaca     1200

uuuucaaacg gaugcgauua cguaucaaau aaaggaguag acaccguauc cguaggaaau     1260

acucucuacu gcguaaacaa acaagaagga caaucccuau acguaaaagg cgaaccaauc     1320

auuaacuuuu acgacccacu uguauuucca ucagacgaau uugaugccuc aauaucccaa     1380

gucaaugaaa aaauaaacca aagucuagca uucauccgaa aaucagauga acuuuuacac     1440

aacguaaacg ccggaaaauc aacaacaaac aucaugauca caacaaucau cauaguaaua     1500

auaguuauac uacuuuccuu aauagcaguc ggccuacuac ucuacugcaa agcacgaucc     1560

acaccaguaa ccuuaucuaa agaccaacuc ucaggcauaa acaacauagc auucucaaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3480
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut3 (opt11)

<400>  3480
gggagaaagc uuaccaugga acuccucauc cuuaaagcaa acgccaucac aaccauccuc       60

acagcaguca cuuucugcuu cgcauccgga caaaacauca cagaagaguu cuaucaaucc      120

acgugcuccg caguuuccaa aggauaccuu ggagccuuac gaaccggcug guacaccucc      180

gucaucacca uagaacucag caacaucaaa gaaaucaaau gcaacggaac cgacgcaaaa      240

gucaaacuca ucaaacaaga acuagacaaa uacaaaaacg cagucaccga ccuccaacua      300

cucaugcaau caacccccgc aaccggcucc ggcuccgcca ucugcuccgg aguagccgua      360

ugcaaagucc uccaccucga aggcgaaguu aacaagauca aguccgcacu ccuaucaacc      420

aacaaagcag ucgucucccu auccaacggc gucuccguau uaacauucaa aguccucgac      480

cucaaaaacu acauagacaa acagcuacuc cccauccuaa acaaacaauc cugcuccauc      540

cccaacaucg aaacugucau cgaguuccaa cagaaaaaca accgccuccu agaaaucacc      600

cgagaguucu ccguaaacgc cggcgucacu acccccgucu cuaccuauau gcuaaccaac      660

ucugaacucc uaucccuaau caacgauaug cccauaacua acgaccaaaa gaaacuuaug      720

uccaacaacg uacaaauagu ccggcaacaa ucauacucua ucaugugcau caucaaagaa      780

gaaguacuug ccuacguugu ccaacuccca cuauacggcg ucauagacac uccaugcugg      840

aaacuucaca ccucaccccu cugcaccacu aacacuaaag aaggcucuaa caucugccuu      900

acccgcaccg accgcggaug guacugcgac aacgcaggcu caguuagcuu cuucccacaa      960

gccgaaaccu gcaaagucca gucaaaccgu gucuucugcg auaccaugaa cucgcucacc     1020

cucccuuccg aagucaaccu cugcaacguc gacaucuuca accccaaaua cgacugcaaa     1080

aucaugaccu caaaaaccga cguaucuucu uccgucauca ccucccucgg cgccaucgua     1140

uccugcuacg gcaaaaccaa augcacugca ucaaacaaaa accgaggcau caucaaaacc     1200

uucucgaacg gaugcgacua cguauccaac aagggcgucg acacagucuc cguugguaac     1260

acccucuacu gcgucaacaa acaagaaggc caaucccuau acguaaaagg cgaacccauc     1320

aucaacuucu acgacccccu cgucuucccc agugacgaau uugacgccuc caucucccaa     1380

gucaacgaaa agaucaacca aucccuugcc uucauacgca aauccgacga acuccuacac     1440

aacguuaacg ccggaaaauc aacaaccaac aucaugauca caaccaucau aaucgucaua     1500

aucgucauac uccucucccu cauagccguc ggccugcuau uguacuguaa agcccgcucc     1560

acaccaguca cacuuucaaa agaccaacuc uccgggauca acaacaucgc cuucuccaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  3481
<211>  514
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3481

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg 
        


<210>  3482
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3482
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc gguga                     1545


<210>  3483
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3483
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucugc uccggcgugg ccgugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcgcugcugu ccaccaacaa ggccgugguc      420

agccucucca acggcgugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccgcugua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      900

ggcugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu cuacugcguc     1260

aacaagcagg agggccagag ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguga                     1545


<210>  3484
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3484
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuga                     1545


<210>  3485
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3485
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagau caaaugcaau ggcaccgacg ccaaggugaa acuaauaaag      240

caggaacucg auaaguauaa aaacgcagua acugaccugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuaucugu ucaggcgugg cagucugcaa gguguugcac      360

cucgagggug agguuaauaa aauuaagagc gcccugcuga guacgaacaa agcugugguc      420

ucccucucua auggggugag cguauuaacu uuuaagguuc uggaucuuaa gaacuacauc      480

gacaaacaau ugcugccuau ucuaaauaag caguccuguu caaucccaaa cauagaaacc      540

gugauugagu uccagcagaa aaauaacagg cuccuggaaa ucacacggga guuuaguguc      600

aaugccggag ugacuacccc ggugagcaca uauaugcuua ccaacucuga gcuguugucc      660

cucauuaaug auaugcccau cacgaacgac caaaagaaac ugaugucaaa caauguccag      720

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcguau      780

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      840

ccccugugca ccacuaacac aaaggaaggc uccaauaucu guuugacccg aacggaccgu      900

gggugguacu gcgauaacgc aggaagcgug ucguucuuuc cucaggccga gaccuguaag      960

guucagucua auagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1020

aaucucugca acguggauau auuuaauccc aaauaugacu guaagauuau gaccaguaaa     1080

acagauguaa gcuccucugu uaucacuagc cugggugcua ucgugucaug cuacggcaag     1140

accaaaugua cagccaguaa caagaauagg gggauuauca agaccuucuc caacggaugc     1200

gacuauguca gcaauaaagg cguggacacu gucucugugg guaacacgcu uuacuguguu     1260

aauaagcaag aggggcaguc acuguaugug aaaggagagc cuauuauaaa cuuuuacgau     1320

ccauugguau ucccgaguga cgaauuugau gcaagcaucu cccaggucaa cgagaagauu     1380

aaucagucuc ucgcuuucau ccggaaaucg gacgaacugu uacacaacgu gaaugccggc     1440

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1500

ucccucauag cggucggccu gcuuuuguau ugcaaggccc gcuga                     1545


<210>  3486
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3486
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gauga                     1545


<210>  3487
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3487
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagau caaaugcaau gggaccgacg ccaaggugaa acuuauuaag      240

caggaacugg auaaguauaa aaacgcugug acggaccucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuaucugu agcggggucg ccgugugcaa gguucuccac      360

cuggagggag aggugaauaa aauuaagucc gcgcuucuga gcaccaacaa agccgucgug      420

ucucucucca auggcguuag cgugcugaca uuuaaggucc uugaucugaa gaacuacauc      480

gacaaacaac uccugccuau ucugaauaag cagucuuguu ccaucccgaa cauugaaacc      540

gugaucgagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuagcgug      600

aaugcuggcg ucacaacccc cguuucuaca uauaugcuua ccaacuccga gcugcucagc      660

cugauuaaug auaugccuau caccaacgac caaaagaaac uuauguccaa caaugugcag      720

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggccuau      780

gugguucaac ucccccugua cggggugauc gauacaccuu guuggaaacu gcauacgagc      840

ccccucugca ccacaaacac caaggaagga uccaauauuu gucugacacg gaccgaccgc      900

ggcugguacu gcgauaacgc ugggucuguc uccuucuuuc cucaggccga gacguguaag      960

gugcagagca auagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1020

aaucucugca acgucgauau cuuuaauccc aaauaugacu guaagauuau gaccuccaaa     1080

acagaugugu cuagcuccgu caucaccagc cugggagcga uugugucuug cuacggcaag     1140

acaaaaugua cggccuccaa caagaaucgg gggaucauca agaccuucag caacggaugc     1200

gacuauguuu cuaauaaagg cguggacaca gucuccgugg gcaacacccu uuacuguguu     1260

aauaagcaag aggggcagag ccuguaugug aaaggagagc cuauuaucaa cuuuuacgau     1320

ccccucgucu ucccuuccga cgaauuugau gcuucuauua gccaggugaa cgagaagauc     1380

aaucaguccc uggccuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugcuggc     1440

aagagcacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1500

ucccugauug ccguggggcu ccugcuguau ugcaaggcca gauga                     1545


<210>  3488
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3488
auggaauuac uaauccugaa agcaaacgca auuacuacaa uacuaacagc aguaaccuuu       60

ugcuuugccu caggacaaaa cauaacugaa gaauuuuacc aaucaacuug cucagcaguc      120

ucaaaaggcu aucuaggagc acuacgaaca gguugguaua cuucagucau aacaauagaa      180

uuaucaaaca uaaaagaaau uaaauguaac ggaacugacg caaaaguaaa acucaucaaa      240

caagaacucg auaaauacaa aaacgcugua accgacuuac aacuacuaau gcaaucaacu      300

ccagcaacag gcuccggauc cgcaauaugc agugguguag caguaugcaa aguccuacac      360

cuagaaggag aaguaaauaa gauaaaaucu gcucuacuau caacaaauaa agcaguuguc      420

ucccuaucaa auggagucuc aguacucacc uucaaaguau uagaccucaa aaacuacaua      480

gacaaacaac uauuaccaau acucaacaaa caauccugcu ccaucccuaa cauagaaacc      540

guaaucgaau uucaacaaaa aaauaacaga cucuuagaaa uaacuagaga auuuucaguu      600

aaugcaggcg ugacaacacc aguaucaaca uauaugcuaa caaacuccga acuccuaucc      660

cuaauaaacg acaugccaau cacaaacgac caaaaaaaac uaauguccaa caacguacaa      720

aucguaagac aacaaucaua cucuauaaug ugcauaauaa aagaagaagu acuggccuac      780

guaguacaau uaccacucua cggaguaaua gacaccccau gcuggaaacu ccauacauca      840

ccccuaugca caacaaacac aaaagaagga uccaacauau gucucacuag aacagacaga      900

ggcugguacu gcgacaacgc uggauccguc ucauucuucc cccaagcaga aacauguaaa      960

guacaaucua auagaguauu uugugacaca augaacagcc ucacacuacc auccgaaguc     1020

aaccuaugua acguagauau auuuaauccc aaauacgacu gcaaaauaau gacauccaaa     1080

acagauguau caucauccgu uaucaccuca cuaggagcca uaguuucaug cuacggaaaa     1140

acaaaaugca cugcaucuaa caaaaauaga gguauaauaa aaacauuuuc caacggcugc     1200

gacuacgucu caaacaaagg cguagacacc guaucaguag gaaauacauu auauugcgua     1260

aauaaacaag aaggccaauc ccuauacgua aaaggagaac ccaucauaaa cuucuaugac     1320

ccacuuguuu uccccucaga cgaauuugac gccucaauau cacaaguaaa ugaaaaaaua     1380

aaccaaucuc uugccuucau uagaaaauca gacgaauuac uacacaacgu caacgcagga     1440

aaaucaacaa caaacaucau gauaacaacg auaauaauag ucauaauagu aauacuacua     1500

ucauuaaucg cagucggacu ccuauuauau ugcaaagcua gauaa                     1545


<210>  3489
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut3

<400>  3489
auggaacuac ucauacuaaa agccaacgcc auaaccacca uccucaccgc aguaacuuuc       60

ugcuucgcuu ccggccaaaa caucaccgaa gaauuuuacc aaaguaccug cagcgcaguc      120

ucaaaaggau accuaggcgc ccuacgcaca ggcugguaca ccuccgucau uaccaucgaa      180

cucuccaaca ucaaagaaau uaaaugcaac gguacagacg caaaagucaa acucaucaaa      240

caagaacucg acaaauacaa aaacgcaguc accgaccucc aacuccucau gcaauccacc      300

cccgccacag gcucuggcuc cgccaucugc ucaggcguag cagucugcaa aguccugcac      360

cucgaaggcg aagucaacaa aaucaaguca gcccuccucu ccaccaacaa ggccgucgua      420

ucccucucaa acggaguuag cguccucacc uucaaagucc uagaccucaa aaacuacauc      480

gauaaacaac uacuccccau ccuaaacaaa caaucaugcu ccaucccaaa caucgaaacc      540

guaaucgagu uccaacaaaa gaacaaccgc cuccucgaaa ucacacguga guucuccguu      600

aacgccggcg ucaccacccc cgucucuaca uacaugcuca ccaacuccga acuccuuucc      660

cucaucaacg acaugccaau caccaacgac caaaagaaac ucaugucaaa caacguacaa      720

aucguccgac aacaaagcua cuccaucaug ugcaucauca aagaagaagu ccuugcauac      780

gucguucaac uaccccucua cggcguaauc gacacucccu gcuggaaacu ccacaccucc      840

ccgcucugca caaccaacac caaagaaggc agcaacaucu gccucacccg aaccgaccgc      900

ggcugguacu gcgauaacgc cggauccguc uccuucuucc cacaagcaga aacuugcaaa      960

guccaaucca accgcgucuu cugcgacacc augaacuccc ucacacuccc cuccgaaguc     1020

aaccugugca acgucgacau cuucaaccca aaauacgacu gcaaaaucau gaccucaaaa     1080

accgacgucu caucuucugu caucaccucu cucggcgcua ucgucuccug cuauggcaaa     1140

accaaaugca ccgccuccaa caagaaccgc ggcauuauca agaccuucuc caacggcugc     1200

gacuacgucu ccaauaaggg cgucgacacc gucucugucg gcaacacccu uuacugcgua     1260

aacaaacaag aaggucaauc ucucuacguc aaaggagaac ccaucaucaa cuucuacgac     1320

ccccuggucu uccccuccga cgaguucgau gcaucaaucu cccaagucaa cgaaaagauc     1380

aaccaaucuc ucgcuuucau ccgcaaaucc gacgaacucc uacacaacgu aaacgccggc     1440

aaauccacca caaacaucau gaucaccacc auuaucauag ucaucaucgu cauccuccuc     1500

uccuuaaucg ccguuggccu ccuucucuac ugcaaagccc gauaa                     1545


<210>  3490
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3490
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3491
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3491
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3492
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3492
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3493
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3493
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3494
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3494
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3495
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3495
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3496
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3496
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccugaaagc aaacgcaauu acuacaauac      120

uaacagcagu aaccuuuugc uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacuugcuc agcagucuca aaaggcuauc uaggagcacu acgaacaggu ugguauacuu      240

cagucauaac aauagaauua ucaaacauaa aagaaauuaa auguaacgga acugacgcaa      300

aaguaaaacu caucaaacaa gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac      360

uacuaaugca aucaacucca gcaacaggcu ccggauccgc aauaugcagu gguguagcag      420

uaugcaaagu ccuacaccua gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa      480

caaauaaagc aguugucucc cuaucaaaug gagucucagu acucaccuuc aaaguauuag      540

accucaaaaa cuacauagac aaacaacuau uaccaauacu caacaaacaa uccugcucca      600

ucccuaacau agaaaccgua aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa      660

cuagagaauu uucaguuaau gcaggcguga caacaccagu aucaacauau augcuaacaa      720

acuccgaacu ccuaucccua auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaauc guaagacaac aaucauacuc uauaaugugc auaauaaaag      840

aagaaguacu ggccuacgua guacaauuac cacucuacgg aguaauagac accccaugcu      900

ggaaacucca uacaucaccc cuaugcacaa caaacacaaa agaaggaucc aacauauguc      960

ucacuagaac agacagaggc ugguacugcg acaacgcugg auccgucuca uucuuccccc     1020

aagcagaaac auguaaagua caaucuaaua gaguauuuug ugacacaaug aacagccuca     1080

cacuaccauc cgaagucaac cuauguaacg uagauauauu uaaucccaaa uacgacugca     1140

aaauaaugac auccaaaaca gauguaucau cauccguuau caccucacua ggagccauag     1200

uuucaugcua cggaaaaaca aaaugcacug caucuaacaa aaauagaggu auaauaaaaa     1260

cauuuuccaa cggcugcgac uacgucucaa acaaaggcgu agacaccgua ucaguaggaa     1320

auacauuaua uugcguaaau aaacaagaag gccaaucccu auacguaaaa ggagaaccca     1380

ucauaaacuu cuaugaccca cuuguuuucc ccucagacga auuugacgcc ucaauaucac     1440

aaguaaauga aaaaauaaac caaucucuug ccuucauuag aaaaucagac gaauuacuac     1500

acaacgucaa cgcaggaaaa ucaacaacaa acaucaugau aacaacgaua auaauaguca     1560

uaauaguaau acuacuauca uuaaucgcag ucggacuccu auuauauugc aaagcuagau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3497
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3497
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuaaaagc caacgccaua accaccaucc      120

ucaccgcagu aacuuucugc uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa      180

guaccugcag cgcagucuca aaaggauacc uaggcgcccu acgcacaggc ugguacaccu      240

ccgucauuac caucgaacuc uccaacauca aagaaauuaa augcaacggu acagacgcaa      300

aagucaaacu caucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaccuccaac      360

uccucaugca auccaccccc gccacaggcu cuggcuccgc caucugcuca ggcguagcag      420

ucugcaaagu ccugcaccuc gaaggcgaag ucaacaaaau caagucagcc cuccucucca      480

ccaacaaggc cgucguaucc cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacuac uccccauccu aaacaaacaa ucaugcucca      600

ucccaaacau cgaaaccgua aucgaguucc aacaaaagaa caaccgccuc cucgaaauca      660

cacgugaguu cuccguuaac gccggcguca ccacccccgu cucuacauac augcucacca      720

acuccgaacu ccuuucccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguacaaauc guccgacaac aaagcuacuc caucaugugc aucaucaaag      840

aagaaguccu ugcauacguc guucaacuac cccucuacgg cguaaucgac acucccugcu      900

ggaaacucca caccuccccg cucugcacaa ccaacaccaa agaaggcagc aacaucugcc      960

ucacccgaac cgaccgcggc ugguacugcg auaacgccgg auccgucucc uucuucccac     1020

aagcagaaac uugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cacuccccuc cgaagucaac cugugcaacg ucgacaucuu caacccaaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacgucucau cuucugucau caccucucuc ggcgcuaucg     1200

ucuccugcua uggcaaaacc aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca auaagggcgu cgacaccguc ucugucggca     1320

acacccuuua cugcguaaac aaacaagaag gucaaucucu cuacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cuggucuucc ccuccgacga guucgaugca ucaaucuccc     1440

aagucaacga aaagaucaac caaucucucg cuuucauccg caaauccgac gaacuccuac     1500

acaacguaaa cgccggcaaa uccaccacaa acaucaugau caccaccauu aucauaguca     1560

ucaucgucau ccuccucucc uuaaucgccg uuggccuccu ucucuacugc aaagcccgau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  3498
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3498
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3499
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3499
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3500
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3500
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3501
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3501
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3502
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3502
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3503
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3503
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3504
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3504
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccugaaagca      120

aacgcaauua cuacaauacu aacagcagua accuuuugcu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacuugcuca gcagucucaa aaggcuaucu aggagcacua      240

cgaacagguu gguauacuuc agucauaaca auagaauuau caaacauaaa agaaauuaaa      300

uguaacggaa cugacgcaaa aguaaaacuc aucaaacaag aacucgauaa auacaaaaac      360

gcuguaaccg acuuacaacu acuaaugcaa ucaacuccag caacaggcuc cggauccgca      420

auaugcagug guguagcagu augcaaaguc cuacaccuag aaggagaagu aaauaagaua      480

aaaucugcuc uacuaucaac aaauaaagca guugucuccc uaucaaaugg agucucagua      540

cucaccuuca aaguauuaga ccucaaaaac uacauagaca aacaacuauu accaauacuc      600

aacaaacaau ccugcuccau cccuaacaua gaaaccguaa ucgaauuuca acaaaaaaau      660

aacagacucu uagaaauaac uagagaauuu ucaguuaaug caggcgugac aacaccagua      720

ucaacauaua ugcuaacaaa cuccgaacuc cuaucccuaa uaaacgacau gccaaucaca      780

aacgaccaaa aaaaacuaau guccaacaac guacaaaucg uaagacaaca aucauacucu      840

auaaugugca uaauaaaaga agaaguacug gccuacguag uacaauuacc acucuacgga      900

guaauagaca ccccaugcug gaaacuccau acaucacccc uaugcacaac aaacacaaaa      960

gaaggaucca acauaugucu cacuagaaca gacagaggcu gguacugcga caacgcugga     1020

uccgucucau ucuuccccca agcagaaaca uguaaaguac aaucuaauag aguauuuugu     1080

gacacaauga acagccucac acuaccaucc gaagucaacc uauguaacgu agauauauuu     1140

aaucccaaau acgacugcaa aauaaugaca uccaaaacag auguaucauc auccguuauc     1200

accucacuag gagccauagu uucaugcuac ggaaaaacaa aaugcacugc aucuaacaaa     1260

aauagaggua uaauaaaaac auuuuccaac ggcugcgacu acgucucaaa caaaggcgua     1320

gacaccguau caguaggaaa uacauuauau ugcguaaaua aacaagaagg ccaaucccua     1380

uacguaaaag gagaacccau cauaaacuuc uaugacccac uuguuuuccc cucagacgaa     1440

uuugacgccu caauaucaca aguaaaugaa aaaauaaacc aaucucuugc cuucauuaga     1500

aaaucagacg aauuacuaca caacgucaac gcaggaaaau caacaacaaa caucaugaua     1560

acaacgauaa uaauagucau aauaguaaua cuacuaucau uaaucgcagu cggacuccua     1620

uuauauugca aagcuagaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3505
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3505
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuaaaagcc      120

aacgccauaa ccaccauccu caccgcagua acuuucugcu ucgcuuccgg ccaaaacauc      180

accgaagaau uuuaccaaag uaccugcagc gcagucucaa aaggauaccu aggcgcccua      240

cgcacaggcu gguacaccuc cgucauuacc aucgaacucu ccaacaucaa agaaauuaaa      300

ugcaacggua cagacgcaaa agucaaacuc aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg accuccaacu ccucaugcaa uccacccccg ccacaggcuc uggcuccgcc      420

aucugcucag gcguagcagu cugcaaaguc cugcaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccucuccac caacaaggcc gucguauccc ucucaaacgg aguuagcguc      540

cucaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuacu ccccauccua      600

aacaaacaau caugcuccau cccaaacauc gaaaccguaa ucgaguucca acaaaagaac      660

aaccgccucc ucgaaaucac acgugaguuc uccguuaacg ccggcgucac cacccccguc      720

ucuacauaca ugcucaccaa cuccgaacuc cuuucccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guacaaaucg uccgacaaca aagcuacucc      840

aucaugugca ucaucaaaga agaaguccuu gcauacgucg uucaacuacc ccucuacggc      900

guaaucgaca cucccugcug gaaacuccac accuccccgc ucugcacaac caacaccaaa      960

gaaggcagca acaucugccu cacccgaacc gaccgcggcu gguacugcga uaacgccgga     1020

uccgucuccu ucuucccaca agcagaaacu ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac acuccccucc gaagucaacc ugugcaacgu cgacaucuuc     1140

aacccaaaau acgacugcaa aaucaugacc ucaaaaaccg acgucucauc uucugucauc     1200

accucucucg gcgcuaucgu cuccugcuau ggcaaaacca aaugcaccgc cuccaacaag     1260

aaccgcggca uuaucaagac cuucuccaac ggcugcgacu acgucuccaa uaagggcguc     1320

gacaccgucu cugucggcaa cacccuuuac ugcguaaaca aacaagaagg ucaaucucuc     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc uggucuuccc cuccgacgag     1440

uucgaugcau caaucuccca agucaacgaa aagaucaacc aaucucucgc uuucauccgc     1500

aaauccgacg aacuccuaca caacguaaac gccggcaaau ccaccacaaa caucaugauc     1560

accaccauua ucauagucau caucgucauc cuccucuccu uaaucgccgu uggccuccuu     1620

cucuacugca aagcccgaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  3506
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3506
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3507
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3507
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3508
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3508
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3509
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3509
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3510
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3510
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3511
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3511
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3512
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3512
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ugaaagcaaa cgcaauuacu acaauacuaa cagcaguaac cuuuugcuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa cuugcucagc agucucaaaa      300

ggcuaucuag gagcacuacg aacagguugg uauacuucag ucauaacaau agaauuauca      360

aacauaaaag aaauuaaaug uaacggaacu gacgcaaaag uaaaacucau caaacaagaa      420

cucgauaaau acaaaaacgc uguaaccgac uuacaacuac uaaugcaauc aacuccagca      480

acaggcuccg gauccgcaau augcaguggu guagcaguau gcaaaguccu acaccuagaa      540

ggagaaguaa auaagauaaa aucugcucua cuaucaacaa auaaagcagu ugucucccua      600

ucaaauggag ucucaguacu caccuucaaa guauuagacc ucaaaaacua cauagacaaa      660

caacuauuac caauacucaa caaacaaucc ugcuccaucc cuaacauaga aaccguaauc      720

gaauuucaac aaaaaaauaa cagacucuua gaaauaacua gagaauuuuc aguuaaugca      780

ggcgugacaa caccaguauc aacauauaug cuaacaaacu ccgaacuccu aucccuaaua      840

aacgacaugc caaucacaaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaaucgua      900

agacaacaau cauacucuau aaugugcaua auaaaagaag aaguacuggc cuacguagua      960

caauuaccac ucuacggagu aauagacacc ccaugcugga aacuccauac aucaccccua     1020

ugcacaacaa acacaaaaga aggauccaac auaugucuca cuagaacaga cagaggcugg     1080

uacugcgaca acgcuggauc cgucucauuc uucccccaag cagaaacaug uaaaguacaa     1140

ucuaauagag uauuuuguga cacaaugaac agccucacac uaccauccga agucaaccua     1200

uguaacguag auauauuuaa ucccaaauac gacugcaaaa uaaugacauc caaaacagau     1260

guaucaucau ccguuaucac cucacuagga gccauaguuu caugcuacgg aaaaacaaaa     1320

ugcacugcau cuaacaaaaa uagagguaua auaaaaacau uuuccaacgg cugcgacuac     1380

gucucaaaca aaggcguaga caccguauca guaggaaaua cauuauauug cguaaauaaa     1440

caagaaggcc aaucccuaua cguaaaagga gaacccauca uaaacuucua ugacccacuu     1500

guuuuccccu cagacgaauu ugacgccuca auaucacaag uaaaugaaaa aauaaaccaa     1560

ucucuugccu ucauuagaaa aucagacgaa uuacuacaca acgucaacgc aggaaaauca     1620

acaacaaaca ucaugauaac aacgauaaua auagucauaa uaguaauacu acuaucauua     1680

aucgcagucg gacuccuauu auauugcaaa gcuagauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3513
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3513
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uaaaagccaa cgccauaacc accauccuca ccgcaguaac uuucugcuuc      240

gcuuccggcc aaaacaucac cgaagaauuu uaccaaagua ccugcagcgc agucucaaaa      300

ggauaccuag gcgcccuacg cacaggcugg uacaccuccg ucauuaccau cgaacucucc      360

aacaucaaag aaauuaaaug caacgguaca gacgcaaaag ucaaacucau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgac cuccaacucc ucaugcaauc cacccccgcc      480

acaggcucug gcuccgccau cugcucaggc guagcagucu gcaaaguccu gcaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cucuccacca acaaggccgu cguaucccuc      600

ucaaacggag uuagcguccu caccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuacucc ccauccuaaa caaacaauca ugcuccaucc caaacaucga aaccguaauc      720

gaguuccaac aaaagaacaa ccgccuccuc gaaaucacac gugaguucuc cguuaacgcc      780

ggcgucacca cccccgucuc uacauacaug cucaccaacu ccgaacuccu uucccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaaucguc      900

cgacaacaaa gcuacuccau caugugcauc aucaaagaag aaguccuugc auacgucguu      960

caacuacccc ucuacggcgu aaucgacacu cccugcugga aacuccacac cuccccgcuc     1020

ugcacaacca acaccaaaga aggcagcaac aucugccuca cccgaaccga ccgcggcugg     1080

uacugcgaua acgccggauc cgucuccuuc uucccacaag cagaaacuug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucacac uccccuccga agucaaccug     1200

ugcaacgucg acaucuucaa cccaaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

gucucaucuu cugucaucac cucucucggc gcuaucgucu ccugcuaugg caaaaccaaa     1320

ugcaccgccu ccaacaagaa ccgcggcauu aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaua agggcgucga caccgucucu gucggcaaca cccuuuacug cguaaacaaa     1440

caagaagguc aaucucucua cgucaaagga gaacccauca ucaacuucua cgacccccug     1500

gucuuccccu ccgacgaguu cgaugcauca aucucccaag ucaacgaaaa gaucaaccaa     1560

ucucucgcuu ucauccgcaa auccgacgaa cuccuacaca acguaaacgc cggcaaaucc     1620

accacaaaca ucaugaucac caccauuauc auagucauca ucgucauccu ccucuccuua     1680

aucgccguug gccuccuucu cuacugcaaa gcccgauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  3514
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3514
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3515
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3515
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3516
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3516
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3517
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3517
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3518
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3518
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3519
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3519
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3520
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3520
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu gaaagcaaac gcaauuacua caauacuaac agcaguaacc      180

uuuugcuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac uugcucagca      240

gucucaaaag gcuaucuagg agcacuacga acagguuggu auacuucagu cauaacaaua      300

gaauuaucaa acauaaaaga aauuaaaugu aacggaacug acgcaaaagu aaaacucauc      360

aaacaagaac ucgauaaaua caaaaacgcu guaaccgacu uacaacuacu aaugcaauca      420

acuccagcaa caggcuccgg auccgcaaua ugcaguggug uagcaguaug caaaguccua      480

caccuagaag gagaaguaaa uaagauaaaa ucugcucuac uaucaacaaa uaaagcaguu      540

gucucccuau caaauggagu cucaguacuc accuucaaag uauuagaccu caaaaacuac      600

auagacaaac aacuauuacc aauacucaac aaacaauccu gcuccauccc uaacauagaa      660

accguaaucg aauuucaaca aaaaaauaac agacucuuag aaauaacuag agaauuuuca      720

guuaaugcag gcgugacaac accaguauca acauauaugc uaacaaacuc cgaacuccua      780

ucccuaauaa acgacaugcc aaucacaaac gaccaaaaaa aacuaauguc caacaacgua      840

caaaucguaa gacaacaauc auacucuaua augugcauaa uaaaagaaga aguacuggcc      900

uacguaguac aauuaccacu cuacggagua auagacaccc caugcuggaa acuccauaca      960

ucaccccuau gcacaacaaa cacaaaagaa ggauccaaca uaugucucac uagaacagac     1020

agaggcuggu acugcgacaa cgcuggaucc gucucauucu ucccccaagc agaaacaugu     1080

aaaguacaau cuaauagagu auuuugugac acaaugaaca gccucacacu accauccgaa     1140

gucaaccuau guaacguaga uauauuuaau cccaaauacg acugcaaaau aaugacaucc     1200

aaaacagaug uaucaucauc cguuaucacc ucacuaggag ccauaguuuc augcuacgga     1260

aaaacaaaau gcacugcauc uaacaaaaau agagguauaa uaaaaacauu uuccaacggc     1320

ugcgacuacg ucucaaacaa aggcguagac accguaucag uaggaaauac auuauauugc     1380

guaaauaaac aagaaggcca aucccuauac guaaaaggag aacccaucau aaacuucuau     1440

gacccacuug uuuuccccuc agacgaauuu gacgccucaa uaucacaagu aaaugaaaaa     1500

auaaaccaau cucuugccuu cauuagaaaa ucagacgaau uacuacacaa cgucaacgca     1560

ggaaaaucaa caacaaacau caugauaaca acgauaauaa uagucauaau aguaauacua     1620

cuaucauuaa ucgcagucgg acuccuauua uauugcaaag cuagauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3521
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3521
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu aaaagccaac gccauaacca ccauccucac cgcaguaacu      180

uucugcuucg cuuccggcca aaacaucacc gaagaauuuu accaaaguac cugcagcgca      240

gucucaaaag gauaccuagg cgcccuacgc acaggcuggu acaccuccgu cauuaccauc      300

gaacucucca acaucaaaga aauuaaaugc aacgguacag acgcaaaagu caaacucauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgacc uccaacuccu caugcaaucc      420

acccccgcca caggcucugg cuccgccauc ugcucaggcg uagcagucug caaaguccug      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc ucuccaccaa caaggccguc      540

guaucccucu caaacggagu uagcguccuc accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuacuccc cauccuaaac aaacaaucau gcuccauccc aaacaucgaa      660

accguaaucg aguuccaaca aaagaacaac cgccuccucg aaaucacacg ugaguucucc      720

guuaacgccg gcgucaccac ccccgucucu acauacaugc ucaccaacuc cgaacuccuu      780

ucccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacgua      840

caaaucgucc gacaacaaag cuacuccauc augugcauca ucaaagaaga aguccuugca      900

uacgucguuc aacuaccccu cuacggcgua aucgacacuc ccugcuggaa acuccacacc      960

uccccgcucu gcacaaccaa caccaaagaa ggcagcaaca ucugccucac ccgaaccgac     1020

cgcggcuggu acugcgauaa cgccggaucc gucuccuucu ucccacaagc agaaacuugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacacu ccccuccgaa     1140

gucaaccugu gcaacgucga caucuucaac ccaaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg ucucaucuuc ugucaucacc ucucucggcg cuaucgucuc cugcuauggc     1260

aaaaccaaau gcaccgccuc caacaagaac cgcggcauua ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaauaa gggcgucgac accgucucug ucggcaacac ccuuuacugc     1380

guaaacaaac aagaagguca aucucucuac gucaaaggag aacccaucau caacuucuac     1440

gacccccugg ucuuccccuc cgacgaguuc gaugcaucaa ucucccaagu caacgaaaag     1500

aucaaccaau cucucgcuuu cauccgcaaa uccgacgaac uccuacacaa cguaaacgcc     1560

ggcaaaucca ccacaaacau caugaucacc accauuauca uagucaucau cgucauccuc     1620

cucuccuuaa ucgccguugg ccuccuucuc uacugcaaag cccgauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  3522
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3522
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3523
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3523
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3524
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3524
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3525
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3525
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3526
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3526
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3527
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3527
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3528
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3528
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccugaaa gcaaacgcaa uuacuacaau acuaacagca      120

guaaccuuuu gcuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacuugc      180

ucagcagucu caaaaggcua ucuaggagca cuacgaacag guugguauac uucagucaua      240

acaauagaau uaucaaacau aaaagaaauu aaauguaacg gaacugacgc aaaaguaaaa      300

cucaucaaac aagaacucga uaaauacaaa aacgcuguaa ccgacuuaca acuacuaaug      360

caaucaacuc cagcaacagg cuccggaucc gcaauaugca gugguguagc aguaugcaaa      420

guccuacacc uagaaggaga aguaaauaag auaaaaucug cucuacuauc aacaaauaaa      480

gcaguugucu cccuaucaaa uggagucuca guacucaccu ucaaaguauu agaccucaaa      540

aacuacauag acaaacaacu auuaccaaua cucaacaaac aauccugcuc caucccuaac      600

auagaaaccg uaaucgaauu ucaacaaaaa aauaacagac ucuuagaaau aacuagagaa      660

uuuucaguua augcaggcgu gacaacacca guaucaacau auaugcuaac aaacuccgaa      720

cuccuauccc uaauaaacga caugccaauc acaaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa ucguaagaca acaaucauac ucuauaaugu gcauaauaaa agaagaagua      840

cuggccuacg uaguacaauu accacucuac ggaguaauag acaccccaug cuggaaacuc      900

cauacaucac cccuaugcac aacaaacaca aaagaaggau ccaacauaug ucucacuaga      960

acagacagag gcugguacug cgacaacgcu ggauccgucu cauucuuccc ccaagcagaa     1020

acauguaaag uacaaucuaa uagaguauuu ugugacacaa ugaacagccu cacacuacca     1080

uccgaaguca accuauguaa cguagauaua uuuaauccca aauacgacug caaaauaaug     1140

acauccaaaa cagauguauc aucauccguu aucaccucac uaggagccau aguuucaugc     1200

uacggaaaaa caaaaugcac ugcaucuaac aaaaauagag guauaauaaa aacauuuucc     1260

aacggcugcg acuacgucuc aaacaaaggc guagacaccg uaucaguagg aaauacauua     1320

uauugcguaa auaaacaaga aggccaaucc cuauacguaa aaggagaacc caucauaaac     1380

uucuaugacc cacuuguuuu ccccucagac gaauuugacg ccucaauauc acaaguaaau     1440

gaaaaaauaa accaaucucu ugccuucauu agaaaaucag acgaauuacu acacaacguc     1500

aacgcaggaa aaucaacaac aaacaucaug auaacaacga uaauaauagu cauaauagua     1560

auacuacuau cauuaaucgc agucggacuc cuauuauauu gcaaagcuag auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3529
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3529
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuaaaa gccaacgcca uaaccaccau ccucaccgca      120

guaacuuucu gcuucgcuuc cggccaaaac aucaccgaag aauuuuacca aaguaccugc      180

agcgcagucu caaaaggaua ccuaggcgcc cuacgcacag gcugguacac cuccgucauu      240

accaucgaac ucuccaacau caaagaaauu aaaugcaacg guacagacgc aaaagucaaa      300

cucaucaaac aagaacucga caaauacaaa aacgcaguca ccgaccucca acuccucaug      360

caauccaccc ccgccacagg cucuggcucc gccaucugcu caggcguagc agucugcaaa      420

guccugcacc ucgaaggcga agucaacaaa aucaagucag cccuccucuc caccaacaag      480

gccgucguau cccucucaaa cggaguuagc guccucaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu acuccccauc cuaaacaaac aaucaugcuc caucccaaac      600

aucgaaaccg uaaucgaguu ccaacaaaag aacaaccgcc uccucgaaau cacacgugag      660

uucuccguua acgccggcgu caccaccccc gucucuacau acaugcucac caacuccgaa      720

cuccuuuccc ucaucaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguacaaa ucguccgaca acaaagcuac uccaucaugu gcaucaucaa agaagaaguc      840

cuugcauacg ucguucaacu accccucuac ggcguaaucg acacucccug cuggaaacuc      900

cacaccuccc cgcucugcac aaccaacacc aaagaaggca gcaacaucug ccucacccga      960

accgaccgcg gcugguacug cgauaacgcc ggauccgucu ccuucuuccc acaagcagaa     1020

acuugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacacucccc     1080

uccgaaguca accugugcaa cgucgacauc uucaacccaa aauacgacug caaaaucaug     1140

accucaaaaa ccgacgucuc aucuucuguc aucaccucuc ucggcgcuau cgucuccugc     1200

uauggcaaaa ccaaaugcac cgccuccaac aagaaccgcg gcauuaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caauaagggc gucgacaccg ucucugucgg caacacccuu     1320

uacugcguaa acaaacaaga aggucaaucu cucuacguca aaggagaacc caucaucaac     1380

uucuacgacc cccuggucuu ccccuccgac gaguucgaug caucaaucuc ccaagucaac     1440

gaaaagauca accaaucucu cgcuuucauc cgcaaauccg acgaacuccu acacaacgua     1500

aacgccggca aauccaccac aaacaucaug aucaccacca uuaucauagu caucaucguc     1560

auccuccucu ccuuaaucgc cguuggccuc cuucucuacu gcaaagcccg auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  3530
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3530
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3531
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3531
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      660

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1500

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1560

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3532
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3532
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3533
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3533
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      480

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      600

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      660

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      720

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      780

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      840

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      900

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      960

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua     1020

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1080

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg     1140

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1200

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1260

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1320

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1380

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1440

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1500

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1560

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1620

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1680

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1740

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3534
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3534
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3535
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3535
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      480

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      600

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      660

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      720

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      780

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      840

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      900

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      960

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug     1020

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc     1080

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc     1140

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1200

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1260

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1320

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1380

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1440

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1500

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1560

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1620

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1680

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1740

cugauugccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3536
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3536
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaauuacuaa uccugaaagc aaacgcaauu acuacaauac uaacagcagu aaccuuuugc      300

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacuugcuc agcagucuca      360

aaaggcuauc uaggagcacu acgaacaggu ugguauacuu cagucauaac aauagaauua      420

ucaaacauaa aagaaauuaa auguaacgga acugacgcaa aaguaaaacu caucaaacaa      480

gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac uacuaaugca aucaacucca      540

gcaacaggcu ccggauccgc aauaugcagu gguguagcag uaugcaaagu ccuacaccua      600

gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa caaauaaagc aguugucucc      660

cuaucaaaug gagucucagu acucaccuuc aaaguauuag accucaaaaa cuacauagac      720

aaacaacuau uaccaauacu caacaaacaa uccugcucca ucccuaacau agaaaccgua      780

aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa cuagagaauu uucaguuaau      840

gcaggcguga caacaccagu aucaacauau augcuaacaa acuccgaacu ccuaucccua      900

auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa uguccaacaa cguacaaauc      960

guaagacaac aaucauacuc uauaaugugc auaauaaaag aagaaguacu ggccuacgua     1020

guacaauuac cacucuacgg aguaauagac accccaugcu ggaaacucca uacaucaccc     1080

cuaugcacaa caaacacaaa agaaggaucc aacauauguc ucacuagaac agacagaggc     1140

ugguacugcg acaacgcugg auccgucuca uucuuccccc aagcagaaac auguaaagua     1200

caaucuaaua gaguauuuug ugacacaaug aacagccuca cacuaccauc cgaagucaac     1260

cuauguaacg uagauauauu uaaucccaaa uacgacugca aaauaaugac auccaaaaca     1320

gauguaucau cauccguuau caccucacua ggagccauag uuucaugcua cggaaaaaca     1380

aaaugcacug caucuaacaa aaauagaggu auaauaaaaa cauuuuccaa cggcugcgac     1440

uacgucucaa acaaaggcgu agacaccgua ucaguaggaa auacauuaua uugcguaaau     1500

aaacaagaag gccaaucccu auacguaaaa ggagaaccca ucauaaacuu cuaugaccca     1560

cuuguuuucc ccucagacga auuugacgcc ucaauaucac aaguaaauga aaaaauaaac     1620

caaucucuug ccuucauuag aaaaucagac gaauuacuac acaacgucaa cgcaggaaaa     1680

ucaacaacaa acaucaugau aacaacgaua auaauaguca uaauaguaau acuacuauca     1740

uuaaucgcag ucggacuccu auuauauugc aaagcuagau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3537
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3537
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuca uacuaaaagc caacgccaua accaccaucc ucaccgcagu aacuuucugc      300

uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa guaccugcag cgcagucuca      360

aaaggauacc uaggcgcccu acgcacaggc ugguacaccu ccgucauuac caucgaacuc      420

uccaacauca aagaaauuaa augcaacggu acagacgcaa aagucaaacu caucaaacaa      480

gaacucgaca aauacaaaaa cgcagucacc gaccuccaac uccucaugca auccaccccc      540

gccacaggcu cuggcuccgc caucugcuca ggcguagcag ucugcaaagu ccugcaccuc      600

gaaggcgaag ucaacaaaau caagucagcc cuccucucca ccaacaaggc cgucguaucc      660

cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag accucaaaaa cuacaucgau      720

aaacaacuac uccccauccu aaacaaacaa ucaugcucca ucccaaacau cgaaaccgua      780

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cacgugaguu cuccguuaac      840

gccggcguca ccacccccgu cucuacauac augcucacca acuccgaacu ccuuucccuc      900

aucaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguacaaauc      960

guccgacaac aaagcuacuc caucaugugc aucaucaaag aagaaguccu ugcauacguc     1020

guucaacuac cccucuacgg cguaaucgac acucccugcu ggaaacucca caccuccccg     1080

cucugcacaa ccaacaccaa agaaggcagc aacaucugcc ucacccgaac cgaccgcggc     1140

ugguacugcg auaacgccgg auccgucucc uucuucccac aagcagaaac uugcaaaguc     1200

caauccaacc gcgucuucug cgacaccaug aacucccuca cacuccccuc cgaagucaac     1260

cugugcaacg ucgacaucuu caacccaaaa uacgacugca aaaucaugac cucaaaaacc     1320

gacgucucau cuucugucau caccucucuc ggcgcuaucg ucuccugcua uggcaaaacc     1380

aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca auaagggcgu cgacaccguc ucugucggca acacccuuua cugcguaaac     1500

aaacaagaag gucaaucucu cuacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1560

cuggucuucc ccuccgacga guucgaugca ucaaucuccc aagucaacga aaagaucaac     1620

caaucucucg cuuucauccg caaauccgac gaacuccuac acaacguaaa cgccggcaaa     1680

uccaccacaa acaucaugau caccaccauu aucauaguca ucaucgucau ccuccucucc     1740

uuaaucgccg uuggccuccu ucucuacugc aaagcccgau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3538
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3538
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3539
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3539
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3540
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3540
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3541
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3541
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      480

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      540

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      600

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      660

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      720

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      780

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg      960

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1260

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1440

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1500

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1560

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3542
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3542
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3543
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3543
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      480

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      540

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      600

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      660

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      720

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      780

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc      960

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1140

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1260

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1440

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1500

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1560

cugauugccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3544
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3544
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaauuacuaa uccugaaagc aaacgcaauu acuacaauac uaacagcagu aaccuuuugc      120

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacuugcuc agcagucuca      180

aaaggcuauc uaggagcacu acgaacaggu ugguauacuu cagucauaac aauagaauua      240

ucaaacauaa aagaaauuaa auguaacgga acugacgcaa aaguaaaacu caucaaacaa      300

gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac uacuaaugca aucaacucca      360

gcaacaggcu ccggauccgc aauaugcagu gguguagcag uaugcaaagu ccuacaccua      420

gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa caaauaaagc aguugucucc      480

cuaucaaaug gagucucagu acucaccuuc aaaguauuag accucaaaaa cuacauagac      540

aaacaacuau uaccaauacu caacaaacaa uccugcucca ucccuaacau agaaaccgua      600

aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa cuagagaauu uucaguuaau      660

gcaggcguga caacaccagu aucaacauau augcuaacaa acuccgaacu ccuaucccua      720

auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa uguccaacaa cguacaaauc      780

guaagacaac aaucauacuc uauaaugugc auaauaaaag aagaaguacu ggccuacgua      840

guacaauuac cacucuacgg aguaauagac accccaugcu ggaaacucca uacaucaccc      900

cuaugcacaa caaacacaaa agaaggaucc aacauauguc ucacuagaac agacagaggc      960

ugguacugcg acaacgcugg auccgucuca uucuuccccc aagcagaaac auguaaagua     1020

caaucuaaua gaguauuuug ugacacaaug aacagccuca cacuaccauc cgaagucaac     1080

cuauguaacg uagauauauu uaaucccaaa uacgacugca aaauaaugac auccaaaaca     1140

gauguaucau cauccguuau caccucacua ggagccauag uuucaugcua cggaaaaaca     1200

aaaugcacug caucuaacaa aaauagaggu auaauaaaaa cauuuuccaa cggcugcgac     1260

uacgucucaa acaaaggcgu agacaccgua ucaguaggaa auacauuaua uugcguaaau     1320

aaacaagaag gccaaucccu auacguaaaa ggagaaccca ucauaaacuu cuaugaccca     1380

cuuguuuucc ccucagacga auuugacgcc ucaauaucac aaguaaauga aaaaauaaac     1440

caaucucuug ccuucauuag aaaaucagac gaauuacuac acaacgucaa cgcaggaaaa     1500

ucaacaacaa acaucaugau aacaacgaua auaauaguca uaauaguaau acuacuauca     1560

uuaaucgcag ucggacuccu auuauauugc aaagcuagau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3545
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3545
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuca uacuaaaagc caacgccaua accaccaucc ucaccgcagu aacuuucugc      120

uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa guaccugcag cgcagucuca      180

aaaggauacc uaggcgcccu acgcacaggc ugguacaccu ccgucauuac caucgaacuc      240

uccaacauca aagaaauuaa augcaacggu acagacgcaa aagucaaacu caucaaacaa      300

gaacucgaca aauacaaaaa cgcagucacc gaccuccaac uccucaugca auccaccccc      360

gccacaggcu cuggcuccgc caucugcuca ggcguagcag ucugcaaagu ccugcaccuc      420

gaaggcgaag ucaacaaaau caagucagcc cuccucucca ccaacaaggc cgucguaucc      480

cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag accucaaaaa cuacaucgau      540

aaacaacuac uccccauccu aaacaaacaa ucaugcucca ucccaaacau cgaaaccgua      600

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cacgugaguu cuccguuaac      660

gccggcguca ccacccccgu cucuacauac augcucacca acuccgaacu ccuuucccuc      720

aucaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguacaaauc      780

guccgacaac aaagcuacuc caucaugugc aucaucaaag aagaaguccu ugcauacguc      840

guucaacuac cccucuacgg cguaaucgac acucccugcu ggaaacucca caccuccccg      900

cucugcacaa ccaacaccaa agaaggcagc aacaucugcc ucacccgaac cgaccgcggc      960

ugguacugcg auaacgccgg auccgucucc uucuucccac aagcagaaac uugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucccuca cacuccccuc cgaagucaac     1080

cugugcaacg ucgacaucuu caacccaaaa uacgacugca aaaucaugac cucaaaaacc     1140

gacgucucau cuucugucau caccucucuc ggcgcuaucg ucuccugcua uggcaaaacc     1200

aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca auaagggcgu cgacaccguc ucugucggca acacccuuua cugcguaaac     1320

aaacaagaag gucaaucucu cuacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1380

cuggucuucc ccuccgacga guucgaugca ucaaucuccc aagucaacga aaagaucaac     1440

caaucucucg cuuucauccg caaauccgac gaacuccuac acaacguaaa cgccggcaaa     1500

uccaccacaa acaucaugau caccaccauu aucauaguca ucaucgucau ccuccucucc     1560

uuaaucgccg uuggccuccu ucucuacugc aaagcccgau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  3546
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3546
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3547
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3547
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3548
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3548
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3549
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3549
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3550
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3550
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3551
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3551
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3552
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3552
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccugaaagc aaacgcaauu acuacaauac      120

uaacagcagu aaccuuuugc uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacuugcuc agcagucuca aaaggcuauc uaggagcacu acgaacaggu ugguauacuu      240

cagucauaac aauagaauua ucaaacauaa aagaaauuaa auguaacgga acugacgcaa      300

aaguaaaacu caucaaacaa gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac      360

uacuaaugca aucaacucca gcaacaggcu ccggauccgc aauaugcagu gguguagcag      420

uaugcaaagu ccuacaccua gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa      480

caaauaaagc aguugucucc cuaucaaaug gagucucagu acucaccuuc aaaguauuag      540

accucaaaaa cuacauagac aaacaacuau uaccaauacu caacaaacaa uccugcucca      600

ucccuaacau agaaaccgua aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa      660

cuagagaauu uucaguuaau gcaggcguga caacaccagu aucaacauau augcuaacaa      720

acuccgaacu ccuaucccua auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaauc guaagacaac aaucauacuc uauaaugugc auaauaaaag      840

aagaaguacu ggccuacgua guacaauuac cacucuacgg aguaauagac accccaugcu      900

ggaaacucca uacaucaccc cuaugcacaa caaacacaaa agaaggaucc aacauauguc      960

ucacuagaac agacagaggc ugguacugcg acaacgcugg auccgucuca uucuuccccc     1020

aagcagaaac auguaaagua caaucuaaua gaguauuuug ugacacaaug aacagccuca     1080

cacuaccauc cgaagucaac cuauguaacg uagauauauu uaaucccaaa uacgacugca     1140

aaauaaugac auccaaaaca gauguaucau cauccguuau caccucacua ggagccauag     1200

uuucaugcua cggaaaaaca aaaugcacug caucuaacaa aaauagaggu auaauaaaaa     1260

cauuuuccaa cggcugcgac uacgucucaa acaaaggcgu agacaccgua ucaguaggaa     1320

auacauuaua uugcguaaau aaacaagaag gccaaucccu auacguaaaa ggagaaccca     1380

ucauaaacuu cuaugaccca cuuguuuucc ccucagacga auuugacgcc ucaauaucac     1440

aaguaaauga aaaaauaaac caaucucuug ccuucauuag aaaaucagac gaauuacuac     1500

acaacgucaa cgcaggaaaa ucaacaacaa acaucaugau aacaacgaua auaauaguca     1560

uaauaguaau acuacuauca uuaaucgcag ucggacuccu auuauauugc aaagcuagau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3553
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3553
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuaaaagc caacgccaua accaccaucc      120

ucaccgcagu aacuuucugc uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa      180

guaccugcag cgcagucuca aaaggauacc uaggcgcccu acgcacaggc ugguacaccu      240

ccgucauuac caucgaacuc uccaacauca aagaaauuaa augcaacggu acagacgcaa      300

aagucaaacu caucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaccuccaac      360

uccucaugca auccaccccc gccacaggcu cuggcuccgc caucugcuca ggcguagcag      420

ucugcaaagu ccugcaccuc gaaggcgaag ucaacaaaau caagucagcc cuccucucca      480

ccaacaaggc cgucguaucc cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacuac uccccauccu aaacaaacaa ucaugcucca      600

ucccaaacau cgaaaccgua aucgaguucc aacaaaagaa caaccgccuc cucgaaauca      660

cacgugaguu cuccguuaac gccggcguca ccacccccgu cucuacauac augcucacca      720

acuccgaacu ccuuucccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguacaaauc guccgacaac aaagcuacuc caucaugugc aucaucaaag      840

aagaaguccu ugcauacguc guucaacuac cccucuacgg cguaaucgac acucccugcu      900

ggaaacucca caccuccccg cucugcacaa ccaacaccaa agaaggcagc aacaucugcc      960

ucacccgaac cgaccgcggc ugguacugcg auaacgccgg auccgucucc uucuucccac     1020

aagcagaaac uugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cacuccccuc cgaagucaac cugugcaacg ucgacaucuu caacccaaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacgucucau cuucugucau caccucucuc ggcgcuaucg     1200

ucuccugcua uggcaaaacc aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca auaagggcgu cgacaccguc ucugucggca     1320

acacccuuua cugcguaaac aaacaagaag gucaaucucu cuacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cuggucuucc ccuccgacga guucgaugca ucaaucuccc     1440

aagucaacga aaagaucaac caaucucucg cuuucauccg caaauccgac gaacuccuac     1500

acaacguaaa cgccggcaaa uccaccacaa acaucaugau caccaccauu aucauaguca     1560

ucaucgucau ccuccucucc uuaaucgccg uuggccuccu ucucuacugc aaagcccgau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3554
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3554
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3555
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3555
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3556
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3556
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3557
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3557
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3558
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3558
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3559
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3559
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3560
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3560
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccugaaagc aaacgcaauu acuacaauac      120

uaacagcagu aaccuuuugc uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacuugcuc agcagucuca aaaggcuauc uaggagcacu acgaacaggu ugguauacuu      240

cagucauaac aauagaauua ucaaacauaa aagaaauuaa auguaacgga acugacgcaa      300

aaguaaaacu caucaaacaa gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac      360

uacuaaugca aucaacucca gcaacaggcu ccggauccgc aauaugcagu gguguagcag      420

uaugcaaagu ccuacaccua gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa      480

caaauaaagc aguugucucc cuaucaaaug gagucucagu acucaccuuc aaaguauuag      540

accucaaaaa cuacauagac aaacaacuau uaccaauacu caacaaacaa uccugcucca      600

ucccuaacau agaaaccgua aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa      660

cuagagaauu uucaguuaau gcaggcguga caacaccagu aucaacauau augcuaacaa      720

acuccgaacu ccuaucccua auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaauc guaagacaac aaucauacuc uauaaugugc auaauaaaag      840

aagaaguacu ggccuacgua guacaauuac cacucuacgg aguaauagac accccaugcu      900

ggaaacucca uacaucaccc cuaugcacaa caaacacaaa agaaggaucc aacauauguc      960

ucacuagaac agacagaggc ugguacugcg acaacgcugg auccgucuca uucuuccccc     1020

aagcagaaac auguaaagua caaucuaaua gaguauuuug ugacacaaug aacagccuca     1080

cacuaccauc cgaagucaac cuauguaacg uagauauauu uaaucccaaa uacgacugca     1140

aaauaaugac auccaaaaca gauguaucau cauccguuau caccucacua ggagccauag     1200

uuucaugcua cggaaaaaca aaaugcacug caucuaacaa aaauagaggu auaauaaaaa     1260

cauuuuccaa cggcugcgac uacgucucaa acaaaggcgu agacaccgua ucaguaggaa     1320

auacauuaua uugcguaaau aaacaagaag gccaaucccu auacguaaaa ggagaaccca     1380

ucauaaacuu cuaugaccca cuuguuuucc ccucagacga auuugacgcc ucaauaucac     1440

aaguaaauga aaaaauaaac caaucucuug ccuucauuag aaaaucagac gaauuacuac     1500

acaacgucaa cgcaggaaaa ucaacaacaa acaucaugau aacaacgaua auaauaguca     1560

uaauaguaau acuacuauca uuaaucgcag ucggacuccu auuauauugc aaagcuagau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3561
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3561
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuaaaagc caacgccaua accaccaucc      120

ucaccgcagu aacuuucugc uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa      180

guaccugcag cgcagucuca aaaggauacc uaggcgcccu acgcacaggc ugguacaccu      240

ccgucauuac caucgaacuc uccaacauca aagaaauuaa augcaacggu acagacgcaa      300

aagucaaacu caucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaccuccaac      360

uccucaugca auccaccccc gccacaggcu cuggcuccgc caucugcuca ggcguagcag      420

ucugcaaagu ccugcaccuc gaaggcgaag ucaacaaaau caagucagcc cuccucucca      480

ccaacaaggc cgucguaucc cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacuac uccccauccu aaacaaacaa ucaugcucca      600

ucccaaacau cgaaaccgua aucgaguucc aacaaaagaa caaccgccuc cucgaaauca      660

cacgugaguu cuccguuaac gccggcguca ccacccccgu cucuacauac augcucacca      720

acuccgaacu ccuuucccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguacaaauc guccgacaac aaagcuacuc caucaugugc aucaucaaag      840

aagaaguccu ugcauacguc guucaacuac cccucuacgg cguaaucgac acucccugcu      900

ggaaacucca caccuccccg cucugcacaa ccaacaccaa agaaggcagc aacaucugcc      960

ucacccgaac cgaccgcggc ugguacugcg auaacgccgg auccgucucc uucuucccac     1020

aagcagaaac uugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cacuccccuc cgaagucaac cugugcaacg ucgacaucuu caacccaaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacgucucau cuucugucau caccucucuc ggcgcuaucg     1200

ucuccugcua uggcaaaacc aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca auaagggcgu cgacaccguc ucugucggca     1320

acacccuuua cugcguaaac aaacaagaag gucaaucucu cuacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cuggucuucc ccuccgacga guucgaugca ucaaucuccc     1440

aagucaacga aaagaucaac caaucucucg cuuucauccg caaauccgac gaacuccuac     1500

acaacguaaa cgccggcaaa uccaccacaa acaucaugau caccaccauu aucauaguca     1560

ucaucgucau ccuccucucc uuaaucgccg uuggccuccu ucucuacugc aaagcccgau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  3562
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3562
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3563
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3563
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3564
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3564
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3565
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3565
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3566
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3566
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3567
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3567
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3568
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3568
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu gaaagcaaac gcaauuacua caauacuaac agcaguaacc      180

uuuugcuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac uugcucagca      240

gucucaaaag gcuaucuagg agcacuacga acagguuggu auacuucagu cauaacaaua      300

gaauuaucaa acauaaaaga aauuaaaugu aacggaacug acgcaaaagu aaaacucauc      360

aaacaagaac ucgauaaaua caaaaacgcu guaaccgacu uacaacuacu aaugcaauca      420

acuccagcaa caggcuccgg auccgcaaua ugcaguggug uagcaguaug caaaguccua      480

caccuagaag gagaaguaaa uaagauaaaa ucugcucuac uaucaacaaa uaaagcaguu      540

gucucccuau caaauggagu cucaguacuc accuucaaag uauuagaccu caaaaacuac      600

auagacaaac aacuauuacc aauacucaac aaacaauccu gcuccauccc uaacauagaa      660

accguaaucg aauuucaaca aaaaaauaac agacucuuag aaauaacuag agaauuuuca      720

guuaaugcag gcgugacaac accaguauca acauauaugc uaacaaacuc cgaacuccua      780

ucccuaauaa acgacaugcc aaucacaaac gaccaaaaaa aacuaauguc caacaacgua      840

caaaucguaa gacaacaauc auacucuaua augugcauaa uaaaagaaga aguacuggcc      900

uacguaguac aauuaccacu cuacggagua auagacaccc caugcuggaa acuccauaca      960

ucaccccuau gcacaacaaa cacaaaagaa ggauccaaca uaugucucac uagaacagac     1020

agaggcuggu acugcgacaa cgcuggaucc gucucauucu ucccccaagc agaaacaugu     1080

aaaguacaau cuaauagagu auuuugugac acaaugaaca gccucacacu accauccgaa     1140

gucaaccuau guaacguaga uauauuuaau cccaaauacg acugcaaaau aaugacaucc     1200

aaaacagaug uaucaucauc cguuaucacc ucacuaggag ccauaguuuc augcuacgga     1260

aaaacaaaau gcacugcauc uaacaaaaau agagguauaa uaaaaacauu uuccaacggc     1320

ugcgacuacg ucucaaacaa aggcguagac accguaucag uaggaaauac auuauauugc     1380

guaaauaaac aagaaggcca aucccuauac guaaaaggag aacccaucau aaacuucuau     1440

gacccacuug uuuuccccuc agacgaauuu gacgccucaa uaucacaagu aaaugaaaaa     1500

auaaaccaau cucuugccuu cauuagaaaa ucagacgaau uacuacacaa cgucaacgca     1560

ggaaaaucaa caacaaacau caugauaaca acgauaauaa uagucauaau aguaauacua     1620

cuaucauuaa ucgcagucgg acuccuauua uauugcaaag cuagauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3569
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3569
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu aaaagccaac gccauaacca ccauccucac cgcaguaacu      180

uucugcuucg cuuccggcca aaacaucacc gaagaauuuu accaaaguac cugcagcgca      240

gucucaaaag gauaccuagg cgcccuacgc acaggcuggu acaccuccgu cauuaccauc      300

gaacucucca acaucaaaga aauuaaaugc aacgguacag acgcaaaagu caaacucauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgacc uccaacuccu caugcaaucc      420

acccccgcca caggcucugg cuccgccauc ugcucaggcg uagcagucug caaaguccug      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc ucuccaccaa caaggccguc      540

guaucccucu caaacggagu uagcguccuc accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuacuccc cauccuaaac aaacaaucau gcuccauccc aaacaucgaa      660

accguaaucg aguuccaaca aaagaacaac cgccuccucg aaaucacacg ugaguucucc      720

guuaacgccg gcgucaccac ccccgucucu acauacaugc ucaccaacuc cgaacuccuu      780

ucccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacgua      840

caaaucgucc gacaacaaag cuacuccauc augugcauca ucaaagaaga aguccuugca      900

uacgucguuc aacuaccccu cuacggcgua aucgacacuc ccugcuggaa acuccacacc      960

uccccgcucu gcacaaccaa caccaaagaa ggcagcaaca ucugccucac ccgaaccgac     1020

cgcggcuggu acugcgauaa cgccggaucc gucuccuucu ucccacaagc agaaacuugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacacu ccccuccgaa     1140

gucaaccugu gcaacgucga caucuucaac ccaaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg ucucaucuuc ugucaucacc ucucucggcg cuaucgucuc cugcuauggc     1260

aaaaccaaau gcaccgccuc caacaagaac cgcggcauua ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaauaa gggcgucgac accgucucug ucggcaacac ccuuuacugc     1380

guaaacaaac aagaagguca aucucucuac gucaaaggag aacccaucau caacuucuac     1440

gacccccugg ucuuccccuc cgacgaguuc gaugcaucaa ucucccaagu caacgaaaag     1500

aucaaccaau cucucgcuuu cauccgcaaa uccgacgaac uccuacacaa cguaaacgcc     1560

ggcaaaucca ccacaaacau caugaucacc accauuauca uagucaucau cgucauccuc     1620

cucuccuuaa ucgccguugg ccuccuucuc uacugcaaag cccgauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  3570
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3570
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3571
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3571
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3572
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3572
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3573
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3573
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3574
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3574
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3575
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3575
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3576
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3576
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccugaaagca      120

aacgcaauua cuacaauacu aacagcagua accuuuugcu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacuugcuca gcagucucaa aaggcuaucu aggagcacua      240

cgaacagguu gguauacuuc agucauaaca auagaauuau caaacauaaa agaaauuaaa      300

uguaacggaa cugacgcaaa aguaaaacuc aucaaacaag aacucgauaa auacaaaaac      360

gcuguaaccg acuuacaacu acuaaugcaa ucaacuccag caacaggcuc cggauccgca      420

auaugcagug guguagcagu augcaaaguc cuacaccuag aaggagaagu aaauaagaua      480

aaaucugcuc uacuaucaac aaauaaagca guugucuccc uaucaaaugg agucucagua      540

cucaccuuca aaguauuaga ccucaaaaac uacauagaca aacaacuauu accaauacuc      600

aacaaacaau ccugcuccau cccuaacaua gaaaccguaa ucgaauuuca acaaaaaaau      660

aacagacucu uagaaauaac uagagaauuu ucaguuaaug caggcgugac aacaccagua      720

ucaacauaua ugcuaacaaa cuccgaacuc cuaucccuaa uaaacgacau gccaaucaca      780

aacgaccaaa aaaaacuaau guccaacaac guacaaaucg uaagacaaca aucauacucu      840

auaaugugca uaauaaaaga agaaguacug gccuacguag uacaauuacc acucuacgga      900

guaauagaca ccccaugcug gaaacuccau acaucacccc uaugcacaac aaacacaaaa      960

gaaggaucca acauaugucu cacuagaaca gacagaggcu gguacugcga caacgcugga     1020

uccgucucau ucuuccccca agcagaaaca uguaaaguac aaucuaauag aguauuuugu     1080

gacacaauga acagccucac acuaccaucc gaagucaacc uauguaacgu agauauauuu     1140

aaucccaaau acgacugcaa aauaaugaca uccaaaacag auguaucauc auccguuauc     1200

accucacuag gagccauagu uucaugcuac ggaaaaacaa aaugcacugc aucuaacaaa     1260

aauagaggua uaauaaaaac auuuuccaac ggcugcgacu acgucucaaa caaaggcgua     1320

gacaccguau caguaggaaa uacauuauau ugcguaaaua aacaagaagg ccaaucccua     1380

uacguaaaag gagaacccau cauaaacuuc uaugacccac uuguuuuccc cucagacgaa     1440

uuugacgccu caauaucaca aguaaaugaa aaaauaaacc aaucucuugc cuucauuaga     1500

aaaucagacg aauuacuaca caacgucaac gcaggaaaau caacaacaaa caucaugaua     1560

acaacgauaa uaauagucau aauaguaaua cuacuaucau uaaucgcagu cggacuccua     1620

uuauauugca aagcuagaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3577
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3577
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuaaaagcc      120

aacgccauaa ccaccauccu caccgcagua acuuucugcu ucgcuuccgg ccaaaacauc      180

accgaagaau uuuaccaaag uaccugcagc gcagucucaa aaggauaccu aggcgcccua      240

cgcacaggcu gguacaccuc cgucauuacc aucgaacucu ccaacaucaa agaaauuaaa      300

ugcaacggua cagacgcaaa agucaaacuc aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg accuccaacu ccucaugcaa uccacccccg ccacaggcuc uggcuccgcc      420

aucugcucag gcguagcagu cugcaaaguc cugcaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccucuccac caacaaggcc gucguauccc ucucaaacgg aguuagcguc      540

cucaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuacu ccccauccua      600

aacaaacaau caugcuccau cccaaacauc gaaaccguaa ucgaguucca acaaaagaac      660

aaccgccucc ucgaaaucac acgugaguuc uccguuaacg ccggcgucac cacccccguc      720

ucuacauaca ugcucaccaa cuccgaacuc cuuucccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guacaaaucg uccgacaaca aagcuacucc      840

aucaugugca ucaucaaaga agaaguccuu gcauacgucg uucaacuacc ccucuacggc      900

guaaucgaca cucccugcug gaaacuccac accuccccgc ucugcacaac caacaccaaa      960

gaaggcagca acaucugccu cacccgaacc gaccgcggcu gguacugcga uaacgccgga     1020

uccgucuccu ucuucccaca agcagaaacu ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac acuccccucc gaagucaacc ugugcaacgu cgacaucuuc     1140

aacccaaaau acgacugcaa aaucaugacc ucaaaaaccg acgucucauc uucugucauc     1200

accucucucg gcgcuaucgu cuccugcuau ggcaaaacca aaugcaccgc cuccaacaag     1260

aaccgcggca uuaucaagac cuucuccaac ggcugcgacu acgucuccaa uaagggcguc     1320

gacaccgucu cugucggcaa cacccuuuac ugcguaaaca aacaagaagg ucaaucucuc     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc uggucuuccc cuccgacgag     1440

uucgaugcau caaucuccca agucaacgaa aagaucaacc aaucucucgc uuucauccgc     1500

aaauccgacg aacuccuaca caacguaaac gccggcaaau ccaccacaaa caucaugauc     1560

accaccauua ucauagucau caucgucauc cuccucuccu uaaucgccgu uggccuccuu     1620

cucuacugca aagcccgaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  3578
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3578
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3579
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3579
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3580
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3580
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3581
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3581
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3582
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3582
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3583
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3583
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3584
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3584
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu gaaagcaaac gcaauuacua caauacuaac agcaguaacc      180

uuuugcuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac uugcucagca      240

gucucaaaag gcuaucuagg agcacuacga acagguuggu auacuucagu cauaacaaua      300

gaauuaucaa acauaaaaga aauuaaaugu aacggaacug acgcaaaagu aaaacucauc      360

aaacaagaac ucgauaaaua caaaaacgcu guaaccgacu uacaacuacu aaugcaauca      420

acuccagcaa caggcuccgg auccgcaaua ugcaguggug uagcaguaug caaaguccua      480

caccuagaag gagaaguaaa uaagauaaaa ucugcucuac uaucaacaaa uaaagcaguu      540

gucucccuau caaauggagu cucaguacuc accuucaaag uauuagaccu caaaaacuac      600

auagacaaac aacuauuacc aauacucaac aaacaauccu gcuccauccc uaacauagaa      660

accguaaucg aauuucaaca aaaaaauaac agacucuuag aaauaacuag agaauuuuca      720

guuaaugcag gcgugacaac accaguauca acauauaugc uaacaaacuc cgaacuccua      780

ucccuaauaa acgacaugcc aaucacaaac gaccaaaaaa aacuaauguc caacaacgua      840

caaaucguaa gacaacaauc auacucuaua augugcauaa uaaaagaaga aguacuggcc      900

uacguaguac aauuaccacu cuacggagua auagacaccc caugcuggaa acuccauaca      960

ucaccccuau gcacaacaaa cacaaaagaa ggauccaaca uaugucucac uagaacagac     1020

agaggcuggu acugcgacaa cgcuggaucc gucucauucu ucccccaagc agaaacaugu     1080

aaaguacaau cuaauagagu auuuugugac acaaugaaca gccucacacu accauccgaa     1140

gucaaccuau guaacguaga uauauuuaau cccaaauacg acugcaaaau aaugacaucc     1200

aaaacagaug uaucaucauc cguuaucacc ucacuaggag ccauaguuuc augcuacgga     1260

aaaacaaaau gcacugcauc uaacaaaaau agagguauaa uaaaaacauu uuccaacggc     1320

ugcgacuacg ucucaaacaa aggcguagac accguaucag uaggaaauac auuauauugc     1380

guaaauaaac aagaaggcca aucccuauac guaaaaggag aacccaucau aaacuucuau     1440

gacccacuug uuuuccccuc agacgaauuu gacgccucaa uaucacaagu aaaugaaaaa     1500

auaaaccaau cucuugccuu cauuagaaaa ucagacgaau uacuacacaa cgucaacgca     1560

ggaaaaucaa caacaaacau caugauaaca acgauaauaa uagucauaau aguaauacua     1620

cuaucauuaa ucgcagucgg acuccuauua uauugcaaag cuagauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3585
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3585
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu aaaagccaac gccauaacca ccauccucac cgcaguaacu      180

uucugcuucg cuuccggcca aaacaucacc gaagaauuuu accaaaguac cugcagcgca      240

gucucaaaag gauaccuagg cgcccuacgc acaggcuggu acaccuccgu cauuaccauc      300

gaacucucca acaucaaaga aauuaaaugc aacgguacag acgcaaaagu caaacucauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgacc uccaacuccu caugcaaucc      420

acccccgcca caggcucugg cuccgccauc ugcucaggcg uagcagucug caaaguccug      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc ucuccaccaa caaggccguc      540

guaucccucu caaacggagu uagcguccuc accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuacuccc cauccuaaac aaacaaucau gcuccauccc aaacaucgaa      660

accguaaucg aguuccaaca aaagaacaac cgccuccucg aaaucacacg ugaguucucc      720

guuaacgccg gcgucaccac ccccgucucu acauacaugc ucaccaacuc cgaacuccuu      780

ucccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacgua      840

caaaucgucc gacaacaaag cuacuccauc augugcauca ucaaagaaga aguccuugca      900

uacgucguuc aacuaccccu cuacggcgua aucgacacuc ccugcuggaa acuccacacc      960

uccccgcucu gcacaaccaa caccaaagaa ggcagcaaca ucugccucac ccgaaccgac     1020

cgcggcuggu acugcgauaa cgccggaucc gucuccuucu ucccacaagc agaaacuugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacacu ccccuccgaa     1140

gucaaccugu gcaacgucga caucuucaac ccaaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg ucucaucuuc ugucaucacc ucucucggcg cuaucgucuc cugcuauggc     1260

aaaaccaaau gcaccgccuc caacaagaac cgcggcauua ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaauaa gggcgucgac accgucucug ucggcaacac ccuuuacugc     1380

guaaacaaac aagaagguca aucucucuac gucaaaggag aacccaucau caacuucuac     1440

gacccccugg ucuuccccuc cgacgaguuc gaugcaucaa ucucccaagu caacgaaaag     1500

aucaaccaau cucucgcuuu cauccgcaaa uccgacgaac uccuacacaa cguaaacgcc     1560

ggcaaaucca ccacaaacau caugaucacc accauuauca uagucaucau cgucauccuc     1620

cucuccuuaa ucgccguugg ccuccuucuc uacugcaaag cccgauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  3586
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3586
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3587
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3587
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3588
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3588
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3589
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3589
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3590
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3590
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3591
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3591
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3592
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3592
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccugaaagca      120

aacgcaauua cuacaauacu aacagcagua accuuuugcu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacuugcuca gcagucucaa aaggcuaucu aggagcacua      240

cgaacagguu gguauacuuc agucauaaca auagaauuau caaacauaaa agaaauuaaa      300

uguaacggaa cugacgcaaa aguaaaacuc aucaaacaag aacucgauaa auacaaaaac      360

gcuguaaccg acuuacaacu acuaaugcaa ucaacuccag caacaggcuc cggauccgca      420

auaugcagug guguagcagu augcaaaguc cuacaccuag aaggagaagu aaauaagaua      480

aaaucugcuc uacuaucaac aaauaaagca guugucuccc uaucaaaugg agucucagua      540

cucaccuuca aaguauuaga ccucaaaaac uacauagaca aacaacuauu accaauacuc      600

aacaaacaau ccugcuccau cccuaacaua gaaaccguaa ucgaauuuca acaaaaaaau      660

aacagacucu uagaaauaac uagagaauuu ucaguuaaug caggcgugac aacaccagua      720

ucaacauaua ugcuaacaaa cuccgaacuc cuaucccuaa uaaacgacau gccaaucaca      780

aacgaccaaa aaaaacuaau guccaacaac guacaaaucg uaagacaaca aucauacucu      840

auaaugugca uaauaaaaga agaaguacug gccuacguag uacaauuacc acucuacgga      900

guaauagaca ccccaugcug gaaacuccau acaucacccc uaugcacaac aaacacaaaa      960

gaaggaucca acauaugucu cacuagaaca gacagaggcu gguacugcga caacgcugga     1020

uccgucucau ucuuccccca agcagaaaca uguaaaguac aaucuaauag aguauuuugu     1080

gacacaauga acagccucac acuaccaucc gaagucaacc uauguaacgu agauauauuu     1140

aaucccaaau acgacugcaa aauaaugaca uccaaaacag auguaucauc auccguuauc     1200

accucacuag gagccauagu uucaugcuac ggaaaaacaa aaugcacugc aucuaacaaa     1260

aauagaggua uaauaaaaac auuuuccaac ggcugcgacu acgucucaaa caaaggcgua     1320

gacaccguau caguaggaaa uacauuauau ugcguaaaua aacaagaagg ccaaucccua     1380

uacguaaaag gagaacccau cauaaacuuc uaugacccac uuguuuuccc cucagacgaa     1440

uuugacgccu caauaucaca aguaaaugaa aaaauaaacc aaucucuugc cuucauuaga     1500

aaaucagacg aauuacuaca caacgucaac gcaggaaaau caacaacaaa caucaugaua     1560

acaacgauaa uaauagucau aauaguaaua cuacuaucau uaaucgcagu cggacuccua     1620

uuauauugca aagcuagaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3593
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3593
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuaaaagcc      120

aacgccauaa ccaccauccu caccgcagua acuuucugcu ucgcuuccgg ccaaaacauc      180

accgaagaau uuuaccaaag uaccugcagc gcagucucaa aaggauaccu aggcgcccua      240

cgcacaggcu gguacaccuc cgucauuacc aucgaacucu ccaacaucaa agaaauuaaa      300

ugcaacggua cagacgcaaa agucaaacuc aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg accuccaacu ccucaugcaa uccacccccg ccacaggcuc uggcuccgcc      420

aucugcucag gcguagcagu cugcaaaguc cugcaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccucuccac caacaaggcc gucguauccc ucucaaacgg aguuagcguc      540

cucaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuacu ccccauccua      600

aacaaacaau caugcuccau cccaaacauc gaaaccguaa ucgaguucca acaaaagaac      660

aaccgccucc ucgaaaucac acgugaguuc uccguuaacg ccggcgucac cacccccguc      720

ucuacauaca ugcucaccaa cuccgaacuc cuuucccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guacaaaucg uccgacaaca aagcuacucc      840

aucaugugca ucaucaaaga agaaguccuu gcauacgucg uucaacuacc ccucuacggc      900

guaaucgaca cucccugcug gaaacuccac accuccccgc ucugcacaac caacaccaaa      960

gaaggcagca acaucugccu cacccgaacc gaccgcggcu gguacugcga uaacgccgga     1020

uccgucuccu ucuucccaca agcagaaacu ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac acuccccucc gaagucaacc ugugcaacgu cgacaucuuc     1140

aacccaaaau acgacugcaa aaucaugacc ucaaaaaccg acgucucauc uucugucauc     1200

accucucucg gcgcuaucgu cuccugcuau ggcaaaacca aaugcaccgc cuccaacaag     1260

aaccgcggca uuaucaagac cuucuccaac ggcugcgacu acgucuccaa uaagggcguc     1320

gacaccgucu cugucggcaa cacccuuuac ugcguaaaca aacaagaagg ucaaucucuc     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc uggucuuccc cuccgacgag     1440

uucgaugcau caaucuccca agucaacgaa aagaucaacc aaucucucgc uuucauccgc     1500

aaauccgacg aacuccuaca caacguaaac gccggcaaau ccaccacaaa caucaugauc     1560

accaccauua ucauagucau caucgucauc cuccucuccu uaaucgccgu uggccuccuu     1620

cucuacugca aagcccgaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  3594
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3594
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3595
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3595
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3596
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3596
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3597
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3597
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3598
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3598
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3599
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3599
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3600
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3600
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccugaaagca      120

aacgcaauua cuacaauacu aacagcagua accuuuugcu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacuugcuca gcagucucaa aaggcuaucu aggagcacua      240

cgaacagguu gguauacuuc agucauaaca auagaauuau caaacauaaa agaaauuaaa      300

uguaacggaa cugacgcaaa aguaaaacuc aucaaacaag aacucgauaa auacaaaaac      360

gcuguaaccg acuuacaacu acuaaugcaa ucaacuccag caacaggcuc cggauccgca      420

auaugcagug guguagcagu augcaaaguc cuacaccuag aaggagaagu aaauaagaua      480

aaaucugcuc uacuaucaac aaauaaagca guugucuccc uaucaaaugg agucucagua      540

cucaccuuca aaguauuaga ccucaaaaac uacauagaca aacaacuauu accaauacuc      600

aacaaacaau ccugcuccau cccuaacaua gaaaccguaa ucgaauuuca acaaaaaaau      660

aacagacucu uagaaauaac uagagaauuu ucaguuaaug caggcgugac aacaccagua      720

ucaacauaua ugcuaacaaa cuccgaacuc cuaucccuaa uaaacgacau gccaaucaca      780

aacgaccaaa aaaaacuaau guccaacaac guacaaaucg uaagacaaca aucauacucu      840

auaaugugca uaauaaaaga agaaguacug gccuacguag uacaauuacc acucuacgga      900

guaauagaca ccccaugcug gaaacuccau acaucacccc uaugcacaac aaacacaaaa      960

gaaggaucca acauaugucu cacuagaaca gacagaggcu gguacugcga caacgcugga     1020

uccgucucau ucuuccccca agcagaaaca uguaaaguac aaucuaauag aguauuuugu     1080

gacacaauga acagccucac acuaccaucc gaagucaacc uauguaacgu agauauauuu     1140

aaucccaaau acgacugcaa aauaaugaca uccaaaacag auguaucauc auccguuauc     1200

accucacuag gagccauagu uucaugcuac ggaaaaacaa aaugcacugc aucuaacaaa     1260

aauagaggua uaauaaaaac auuuuccaac ggcugcgacu acgucucaaa caaaggcgua     1320

gacaccguau caguaggaaa uacauuauau ugcguaaaua aacaagaagg ccaaucccua     1380

uacguaaaag gagaacccau cauaaacuuc uaugacccac uuguuuuccc cucagacgaa     1440

uuugacgccu caauaucaca aguaaaugaa aaaauaaacc aaucucuugc cuucauuaga     1500

aaaucagacg aauuacuaca caacgucaac gcaggaaaau caacaacaaa caucaugaua     1560

acaacgauaa uaauagucau aauaguaaua cuacuaucau uaaucgcagu cggacuccua     1620

uuauauugca aagcuagaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3601
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3601
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuaaaagcc      120

aacgccauaa ccaccauccu caccgcagua acuuucugcu ucgcuuccgg ccaaaacauc      180

accgaagaau uuuaccaaag uaccugcagc gcagucucaa aaggauaccu aggcgcccua      240

cgcacaggcu gguacaccuc cgucauuacc aucgaacucu ccaacaucaa agaaauuaaa      300

ugcaacggua cagacgcaaa agucaaacuc aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg accuccaacu ccucaugcaa uccacccccg ccacaggcuc uggcuccgcc      420

aucugcucag gcguagcagu cugcaaaguc cugcaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccucuccac caacaaggcc gucguauccc ucucaaacgg aguuagcguc      540

cucaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuacu ccccauccua      600

aacaaacaau caugcuccau cccaaacauc gaaaccguaa ucgaguucca acaaaagaac      660

aaccgccucc ucgaaaucac acgugaguuc uccguuaacg ccggcgucac cacccccguc      720

ucuacauaca ugcucaccaa cuccgaacuc cuuucccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guacaaaucg uccgacaaca aagcuacucc      840

aucaugugca ucaucaaaga agaaguccuu gcauacgucg uucaacuacc ccucuacggc      900

guaaucgaca cucccugcug gaaacuccac accuccccgc ucugcacaac caacaccaaa      960

gaaggcagca acaucugccu cacccgaacc gaccgcggcu gguacugcga uaacgccgga     1020

uccgucuccu ucuucccaca agcagaaacu ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac acuccccucc gaagucaacc ugugcaacgu cgacaucuuc     1140

aacccaaaau acgacugcaa aaucaugacc ucaaaaaccg acgucucauc uucugucauc     1200

accucucucg gcgcuaucgu cuccugcuau ggcaaaacca aaugcaccgc cuccaacaag     1260

aaccgcggca uuaucaagac cuucuccaac ggcugcgacu acgucuccaa uaagggcguc     1320

gacaccgucu cugucggcaa cacccuuuac ugcguaaaca aacaagaagg ucaaucucuc     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc uggucuuccc cuccgacgag     1440

uucgaugcau caaucuccca agucaacgaa aagaucaacc aaucucucgc uuucauccgc     1500

aaauccgacg aacuccuaca caacguaaac gccggcaaau ccaccacaaa caucaugauc     1560

accaccauua ucauagucau caucgucauc cuccucuccu uaaucgccgu uggccuccuu     1620

cucuacugca aagcccgaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3602
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3602
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3603
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3603
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3604
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3604
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3605
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3605
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3606
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3606
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3607
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3607
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3608
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3608
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccugaa agcaaacgca      120

auuacuacaa uacuaacagc aguaaccuuu ugcuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacuug cucagcaguc ucaaaaggcu aucuaggagc acuacgaaca      240

gguugguaua cuucagucau aacaauagaa uuaucaaaca uaaaagaaau uaaauguaac      300

ggaacugacg caaaaguaaa acucaucaaa caagaacucg auaaauacaa aaacgcugua      360

accgacuuac aacuacuaau gcaaucaacu ccagcaacag gcuccggauc cgcaauaugc      420

agugguguag caguaugcaa aguccuacac cuagaaggag aaguaaauaa gauaaaaucu      480

gcucuacuau caacaaauaa agcaguuguc ucccuaucaa auggagucuc aguacucacc      540

uucaaaguau uagaccucaa aaacuacaua gacaaacaac uauuaccaau acucaacaaa      600

caauccugcu ccaucccuaa cauagaaacc guaaucgaau uucaacaaaa aaauaacaga      660

cucuuagaaa uaacuagaga auuuucaguu aaugcaggcg ugacaacacc aguaucaaca      720

uauaugcuaa caaacuccga acuccuaucc cuaauaaacg acaugccaau cacaaacgac      780

caaaaaaaac uaauguccaa caacguacaa aucguaagac aacaaucaua cucuauaaug      840

ugcauaauaa aagaagaagu acuggccuac guaguacaau uaccacucua cggaguaaua      900

gacaccccau gcuggaaacu ccauacauca ccccuaugca caacaaacac aaaagaagga      960

uccaacauau gucucacuag aacagacaga ggcugguacu gcgacaacgc uggauccguc     1020

ucauucuucc cccaagcaga aacauguaaa guacaaucua auagaguauu uugugacaca     1080

augaacagcc ucacacuacc auccgaaguc aaccuaugua acguagauau auuuaauccc     1140

aaauacgacu gcaaaauaau gacauccaaa acagauguau caucauccgu uaucaccuca     1200

cuaggagcca uaguuucaug cuacggaaaa acaaaaugca cugcaucuaa caaaaauaga     1260

gguauaauaa aaacauuuuc caacggcugc gacuacgucu caaacaaagg cguagacacc     1320

guaucaguag gaaauacauu auauugcgua aauaaacaag aaggccaauc ccuauacgua     1380

aaaggagaac ccaucauaaa cuucuaugac ccacuuguuu uccccucaga cgaauuugac     1440

gccucaauau cacaaguaaa ugaaaaaaua aaccaaucuc uugccuucau uagaaaauca     1500

gacgaauuac uacacaacgu caacgcagga aaaucaacaa caaacaucau gauaacaacg     1560

auaauaauag ucauaauagu aauacuacua ucauuaaucg cagucggacu ccuauuauau     1620

ugcaaagcua gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3609
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3609
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuaaa agccaacgcc      120

auaaccacca uccucaccgc aguaacuuuc ugcuucgcuu ccggccaaaa caucaccgaa      180

gaauuuuacc aaaguaccug cagcgcaguc ucaaaaggau accuaggcgc ccuacgcaca      240

ggcugguaca ccuccgucau uaccaucgaa cucuccaaca ucaaagaaau uaaaugcaac      300

gguacagacg caaaagucaa acucaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaccucc aacuccucau gcaauccacc cccgccacag gcucuggcuc cgccaucugc      420

ucaggcguag cagucugcaa aguccugcac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccucu ccaccaacaa ggccgucgua ucccucucaa acggaguuag cguccucacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uacuccccau ccuaaacaaa      600

caaucaugcu ccaucccaaa caucgaaacc guaaucgagu uccaacaaaa gaacaaccgc      660

cuccucgaaa ucacacguga guucuccguu aacgccggcg ucaccacccc cgucucuaca      720

uacaugcuca ccaacuccga acuccuuucc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguacaa aucguccgac aacaaagcua cuccaucaug      840

ugcaucauca aagaagaagu ccuugcauac gucguucaac uaccccucua cggcguaauc      900

gacacucccu gcuggaaacu ccacaccucc ccgcucugca caaccaacac caaagaaggc      960

agcaacaucu gccucacccg aaccgaccgc ggcugguacu gcgauaacgc cggauccguc     1020

uccuucuucc cacaagcaga aacuugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacacuccc cuccgaaguc aaccugugca acgucgacau cuucaaccca     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacgucu caucuucugu caucaccucu     1200

cucggcgcua ucgucuccug cuauggcaaa accaaaugca ccgccuccaa caagaaccgc     1260

ggcauuauca agaccuucuc caacggcugc gacuacgucu ccaauaaggg cgucgacacc     1320

gucucugucg gcaacacccu uuacugcgua aacaaacaag aaggucaauc ucucuacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccuggucu uccccuccga cgaguucgau     1440

gcaucaaucu cccaagucaa cgaaaagauc aaccaaucuc ucgcuuucau ccgcaaaucc     1500

gacgaacucc uacacaacgu aaacgccggc aaauccacca caaacaucau gaucaccacc     1560

auuaucauag ucaucaucgu cauccuccuc uccuuaaucg ccguuggccu ccuucucuac     1620

ugcaaagccc gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  3610
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3610
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3611
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3611
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3612
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3612
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3613
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3613
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3614
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3614
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3615
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3615
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3616
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3616
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccugaaa      120

gcaaacgcaa uuacuacaau acuaacagca guaaccuuuu gcuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacuugc ucagcagucu caaaaggcua ucuaggagca      240

cuacgaacag guugguauac uucagucaua acaauagaau uaucaaacau aaaagaaauu      300

aaauguaacg gaacugacgc aaaaguaaaa cucaucaaac aagaacucga uaaauacaaa      360

aacgcuguaa ccgacuuaca acuacuaaug caaucaacuc cagcaacagg cuccggaucc      420

gcaauaugca gugguguagc aguaugcaaa guccuacacc uagaaggaga aguaaauaag      480

auaaaaucug cucuacuauc aacaaauaaa gcaguugucu cccuaucaaa uggagucuca      540

guacucaccu ucaaaguauu agaccucaaa aacuacauag acaaacaacu auuaccaaua      600

cucaacaaac aauccugcuc caucccuaac auagaaaccg uaaucgaauu ucaacaaaaa      660

aauaacagac ucuuagaaau aacuagagaa uuuucaguua augcaggcgu gacaacacca      720

guaucaacau auaugcuaac aaacuccgaa cuccuauccc uaauaaacga caugccaauc      780

acaaacgacc aaaaaaaacu aauguccaac aacguacaaa ucguaagaca acaaucauac      840

ucuauaaugu gcauaauaaa agaagaagua cuggccuacg uaguacaauu accacucuac      900

ggaguaauag acaccccaug cuggaaacuc cauacaucac cccuaugcac aacaaacaca      960

aaagaaggau ccaacauaug ucucacuaga acagacagag gcugguacug cgacaacgcu     1020

ggauccgucu cauucuuccc ccaagcagaa acauguaaag uacaaucuaa uagaguauuu     1080

ugugacacaa ugaacagccu cacacuacca uccgaaguca accuauguaa cguagauaua     1140

uuuaauccca aauacgacug caaaauaaug acauccaaaa cagauguauc aucauccguu     1200

aucaccucac uaggagccau aguuucaugc uacggaaaaa caaaaugcac ugcaucuaac     1260

aaaaauagag guauaauaaa aacauuuucc aacggcugcg acuacgucuc aaacaaaggc     1320

guagacaccg uaucaguagg aaauacauua uauugcguaa auaaacaaga aggccaaucc     1380

cuauacguaa aaggagaacc caucauaaac uucuaugacc cacuuguuuu ccccucagac     1440

gaauuugacg ccucaauauc acaaguaaau gaaaaaauaa accaaucucu ugccuucauu     1500

agaaaaucag acgaauuacu acacaacguc aacgcaggaa aaucaacaac aaacaucaug     1560

auaacaacga uaauaauagu cauaauagua auacuacuau cauuaaucgc agucggacuc     1620

cuauuauauu gcaaagcuag auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3617
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3617
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuaaaa      120

gccaacgcca uaaccaccau ccucaccgca guaacuuucu gcuucgcuuc cggccaaaac      180

aucaccgaag aauuuuacca aaguaccugc agcgcagucu caaaaggaua ccuaggcgcc      240

cuacgcacag gcugguacac cuccgucauu accaucgaac ucuccaacau caaagaaauu      300

aaaugcaacg guacagacgc aaaagucaaa cucaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaccucca acuccucaug caauccaccc ccgccacagg cucuggcucc      420

gccaucugcu caggcguagc agucugcaaa guccugcacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccucuc caccaacaag gccgucguau cccucucaaa cggaguuagc      540

guccucaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu acuccccauc      600

cuaaacaaac aaucaugcuc caucccaaac aucgaaaccg uaaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacacgugag uucuccguua acgccggcgu caccaccccc      720

gucucuacau acaugcucac caacuccgaa cuccuuuccc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguacaaa ucguccgaca acaaagcuac      840

uccaucaugu gcaucaucaa agaagaaguc cuugcauacg ucguucaacu accccucuac      900

ggcguaaucg acacucccug cuggaaacuc cacaccuccc cgcucugcac aaccaacacc      960

aaagaaggca gcaacaucug ccucacccga accgaccgcg gcugguacug cgauaacgcc     1020

ggauccgucu ccuucuuccc acaagcagaa acuugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacacucccc uccgaaguca accugugcaa cgucgacauc     1140

uucaacccaa aauacgacug caaaaucaug accucaaaaa ccgacgucuc aucuucuguc     1200

aucaccucuc ucggcgcuau cgucuccugc uauggcaaaa ccaaaugcac cgccuccaac     1260

aagaaccgcg gcauuaucaa gaccuucucc aacggcugcg acuacgucuc caauaagggc     1320

gucgacaccg ucucugucgg caacacccuu uacugcguaa acaaacaaga aggucaaucu     1380

cucuacguca aaggagaacc caucaucaac uucuacgacc cccuggucuu ccccuccgac     1440

gaguucgaug caucaaucuc ccaagucaac gaaaagauca accaaucucu cgcuuucauc     1500

cgcaaauccg acgaacuccu acacaacgua aacgccggca aauccaccac aaacaucaug     1560

aucaccacca uuaucauagu caucaucguc auccuccucu ccuuaaucgc cguuggccuc     1620

cuucucuacu gcaaagcccg auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  3618
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3618
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3619
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3619
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3620
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3620
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3621
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3621
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3622
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3622
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3623
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3623
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3624
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3624
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccugaa agcaaacgca      120

auuacuacaa uacuaacagc aguaaccuuu ugcuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacuug cucagcaguc ucaaaaggcu aucuaggagc acuacgaaca      240

gguugguaua cuucagucau aacaauagaa uuaucaaaca uaaaagaaau uaaauguaac      300

ggaacugacg caaaaguaaa acucaucaaa caagaacucg auaaauacaa aaacgcugua      360

accgacuuac aacuacuaau gcaaucaacu ccagcaacag gcuccggauc cgcaauaugc      420

agugguguag caguaugcaa aguccuacac cuagaaggag aaguaaauaa gauaaaaucu      480

gcucuacuau caacaaauaa agcaguuguc ucccuaucaa auggagucuc aguacucacc      540

uucaaaguau uagaccucaa aaacuacaua gacaaacaac uauuaccaau acucaacaaa      600

caauccugcu ccaucccuaa cauagaaacc guaaucgaau uucaacaaaa aaauaacaga      660

cucuuagaaa uaacuagaga auuuucaguu aaugcaggcg ugacaacacc aguaucaaca      720

uauaugcuaa caaacuccga acuccuaucc cuaauaaacg acaugccaau cacaaacgac      780

caaaaaaaac uaauguccaa caacguacaa aucguaagac aacaaucaua cucuauaaug      840

ugcauaauaa aagaagaagu acuggccuac guaguacaau uaccacucua cggaguaaua      900

gacaccccau gcuggaaacu ccauacauca ccccuaugca caacaaacac aaaagaagga      960

uccaacauau gucucacuag aacagacaga ggcugguacu gcgacaacgc uggauccguc     1020

ucauucuucc cccaagcaga aacauguaaa guacaaucua auagaguauu uugugacaca     1080

augaacagcc ucacacuacc auccgaaguc aaccuaugua acguagauau auuuaauccc     1140

aaauacgacu gcaaaauaau gacauccaaa acagauguau caucauccgu uaucaccuca     1200

cuaggagcca uaguuucaug cuacggaaaa acaaaaugca cugcaucuaa caaaaauaga     1260

gguauaauaa aaacauuuuc caacggcugc gacuacgucu caaacaaagg cguagacacc     1320

guaucaguag gaaauacauu auauugcgua aauaaacaag aaggccaauc ccuauacgua     1380

aaaggagaac ccaucauaaa cuucuaugac ccacuuguuu uccccucaga cgaauuugac     1440

gccucaauau cacaaguaaa ugaaaaaaua aaccaaucuc uugccuucau uagaaaauca     1500

gacgaauuac uacacaacgu caacgcagga aaaucaacaa caaacaucau gauaacaacg     1560

auaauaauag ucauaauagu aauacuacua ucauuaaucg cagucggacu ccuauuauau     1620

ugcaaagcua gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3625
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3625
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuaaa agccaacgcc      120

auaaccacca uccucaccgc aguaacuuuc ugcuucgcuu ccggccaaaa caucaccgaa      180

gaauuuuacc aaaguaccug cagcgcaguc ucaaaaggau accuaggcgc ccuacgcaca      240

ggcugguaca ccuccgucau uaccaucgaa cucuccaaca ucaaagaaau uaaaugcaac      300

gguacagacg caaaagucaa acucaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaccucc aacuccucau gcaauccacc cccgccacag gcucuggcuc cgccaucugc      420

ucaggcguag cagucugcaa aguccugcac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccucu ccaccaacaa ggccgucgua ucccucucaa acggaguuag cguccucacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uacuccccau ccuaaacaaa      600

caaucaugcu ccaucccaaa caucgaaacc guaaucgagu uccaacaaaa gaacaaccgc      660

cuccucgaaa ucacacguga guucuccguu aacgccggcg ucaccacccc cgucucuaca      720

uacaugcuca ccaacuccga acuccuuucc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguacaa aucguccgac aacaaagcua cuccaucaug      840

ugcaucauca aagaagaagu ccuugcauac gucguucaac uaccccucua cggcguaauc      900

gacacucccu gcuggaaacu ccacaccucc ccgcucugca caaccaacac caaagaaggc      960

agcaacaucu gccucacccg aaccgaccgc ggcugguacu gcgauaacgc cggauccguc     1020

uccuucuucc cacaagcaga aacuugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacacuccc cuccgaaguc aaccugugca acgucgacau cuucaaccca     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacgucu caucuucugu caucaccucu     1200

cucggcgcua ucgucuccug cuauggcaaa accaaaugca ccgccuccaa caagaaccgc     1260

ggcauuauca agaccuucuc caacggcugc gacuacgucu ccaauaaggg cgucgacacc     1320

gucucugucg gcaacacccu uuacugcgua aacaaacaag aaggucaauc ucucuacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccuggucu uccccuccga cgaguucgau     1440

gcaucaaucu cccaagucaa cgaaaagauc aaccaaucuc ucgcuuucau ccgcaaaucc     1500

gacgaacucc uacacaacgu aaacgccggc aaauccacca caaacaucau gaucaccacc     1560

auuaucauag ucaucaucgu cauccuccuc uccuuaaucg ccguuggccu ccuucucuac     1620

ugcaaagccc gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  3626
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3626
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3627
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3627
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3628
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3628
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3629
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3629
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3630
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3630
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3631
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3631
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3632
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3632
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ugaaagcaaa cgcaauuacu acaauacuaa cagcaguaac cuuuugcuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa cuugcucagc agucucaaaa      300

ggcuaucuag gagcacuacg aacagguugg uauacuucag ucauaacaau agaauuauca      360

aacauaaaag aaauuaaaug uaacggaacu gacgcaaaag uaaaacucau caaacaagaa      420

cucgauaaau acaaaaacgc uguaaccgac uuacaacuac uaaugcaauc aacuccagca      480

acaggcuccg gauccgcaau augcaguggu guagcaguau gcaaaguccu acaccuagaa      540

ggagaaguaa auaagauaaa aucugcucua cuaucaacaa auaaagcagu ugucucccua      600

ucaaauggag ucucaguacu caccuucaaa guauuagacc ucaaaaacua cauagacaaa      660

caacuauuac caauacucaa caaacaaucc ugcuccaucc cuaacauaga aaccguaauc      720

gaauuucaac aaaaaaauaa cagacucuua gaaauaacua gagaauuuuc aguuaaugca      780

ggcgugacaa caccaguauc aacauauaug cuaacaaacu ccgaacuccu aucccuaaua      840

aacgacaugc caaucacaaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaaucgua      900

agacaacaau cauacucuau aaugugcaua auaaaagaag aaguacuggc cuacguagua      960

caauuaccac ucuacggagu aauagacacc ccaugcugga aacuccauac aucaccccua     1020

ugcacaacaa acacaaaaga aggauccaac auaugucuca cuagaacaga cagaggcugg     1080

uacugcgaca acgcuggauc cgucucauuc uucccccaag cagaaacaug uaaaguacaa     1140

ucuaauagag uauuuuguga cacaaugaac agccucacac uaccauccga agucaaccua     1200

uguaacguag auauauuuaa ucccaaauac gacugcaaaa uaaugacauc caaaacagau     1260

guaucaucau ccguuaucac cucacuagga gccauaguuu caugcuacgg aaaaacaaaa     1320

ugcacugcau cuaacaaaaa uagagguaua auaaaaacau uuuccaacgg cugcgacuac     1380

gucucaaaca aaggcguaga caccguauca guaggaaaua cauuauauug cguaaauaaa     1440

caagaaggcc aaucccuaua cguaaaagga gaacccauca uaaacuucua ugacccacuu     1500

guuuuccccu cagacgaauu ugacgccuca auaucacaag uaaaugaaaa aauaaaccaa     1560

ucucuugccu ucauuagaaa aucagacgaa uuacuacaca acgucaacgc aggaaaauca     1620

acaacaaaca ucaugauaac aacgauaaua auagucauaa uaguaauacu acuaucauua     1680

aucgcagucg gacuccuauu auauugcaaa gcuagauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3633
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3633
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uaaaagccaa cgccauaacc accauccuca ccgcaguaac uuucugcuuc      240

gcuuccggcc aaaacaucac cgaagaauuu uaccaaagua ccugcagcgc agucucaaaa      300

ggauaccuag gcgcccuacg cacaggcugg uacaccuccg ucauuaccau cgaacucucc      360

aacaucaaag aaauuaaaug caacgguaca gacgcaaaag ucaaacucau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgac cuccaacucc ucaugcaauc cacccccgcc      480

acaggcucug gcuccgccau cugcucaggc guagcagucu gcaaaguccu gcaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cucuccacca acaaggccgu cguaucccuc      600

ucaaacggag uuagcguccu caccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuacucc ccauccuaaa caaacaauca ugcuccaucc caaacaucga aaccguaauc      720

gaguuccaac aaaagaacaa ccgccuccuc gaaaucacac gugaguucuc cguuaacgcc      780

ggcgucacca cccccgucuc uacauacaug cucaccaacu ccgaacuccu uucccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaaucguc      900

cgacaacaaa gcuacuccau caugugcauc aucaaagaag aaguccuugc auacgucguu      960

caacuacccc ucuacggcgu aaucgacacu cccugcugga aacuccacac cuccccgcuc     1020

ugcacaacca acaccaaaga aggcagcaac aucugccuca cccgaaccga ccgcggcugg     1080

uacugcgaua acgccggauc cgucuccuuc uucccacaag cagaaacuug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucacac uccccuccga agucaaccug     1200

ugcaacgucg acaucuucaa cccaaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

gucucaucuu cugucaucac cucucucggc gcuaucgucu ccugcuaugg caaaaccaaa     1320

ugcaccgccu ccaacaagaa ccgcggcauu aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaua agggcgucga caccgucucu gucggcaaca cccuuuacug cguaaacaaa     1440

caagaagguc aaucucucua cgucaaagga gaacccauca ucaacuucua cgacccccug     1500

gucuuccccu ccgacgaguu cgaugcauca aucucccaag ucaacgaaaa gaucaaccaa     1560

ucucucgcuu ucauccgcaa auccgacgaa cuccuacaca acguaaacgc cggcaaaucc     1620

accacaaaca ucaugaucac caccauuauc auagucauca ucgucauccu ccucuccuua     1680

aucgccguug gccuccuucu cuacugcaaa gcccgauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  3634
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3634
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3635
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3635
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3636
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3636
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3637
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3637
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3638
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3638
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3639
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3639
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3640
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3640
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccugaaagc aaacgcaauu acuacaauac      120

uaacagcagu aaccuuuugc uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacuugcuc agcagucuca aaaggcuauc uaggagcacu acgaacaggu ugguauacuu      240

cagucauaac aauagaauua ucaaacauaa aagaaauuaa auguaacgga acugacgcaa      300

aaguaaaacu caucaaacaa gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac      360

uacuaaugca aucaacucca gcaacaggcu ccggauccgc aauaugcagu gguguagcag      420

uaugcaaagu ccuacaccua gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa      480

caaauaaagc aguugucucc cuaucaaaug gagucucagu acucaccuuc aaaguauuag      540

accucaaaaa cuacauagac aaacaacuau uaccaauacu caacaaacaa uccugcucca      600

ucccuaacau agaaaccgua aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa      660

cuagagaauu uucaguuaau gcaggcguga caacaccagu aucaacauau augcuaacaa      720

acuccgaacu ccuaucccua auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaauc guaagacaac aaucauacuc uauaaugugc auaauaaaag      840

aagaaguacu ggccuacgua guacaauuac cacucuacgg aguaauagac accccaugcu      900

ggaaacucca uacaucaccc cuaugcacaa caaacacaaa agaaggaucc aacauauguc      960

ucacuagaac agacagaggc ugguacugcg acaacgcugg auccgucuca uucuuccccc     1020

aagcagaaac auguaaagua caaucuaaua gaguauuuug ugacacaaug aacagccuca     1080

cacuaccauc cgaagucaac cuauguaacg uagauauauu uaaucccaaa uacgacugca     1140

aaauaaugac auccaaaaca gauguaucau cauccguuau caccucacua ggagccauag     1200

uuucaugcua cggaaaaaca aaaugcacug caucuaacaa aaauagaggu auaauaaaaa     1260

cauuuuccaa cggcugcgac uacgucucaa acaaaggcgu agacaccgua ucaguaggaa     1320

auacauuaua uugcguaaau aaacaagaag gccaaucccu auacguaaaa ggagaaccca     1380

ucauaaacuu cuaugaccca cuuguuuucc ccucagacga auuugacgcc ucaauaucac     1440

aaguaaauga aaaaauaaac caaucucuug ccuucauuag aaaaucagac gaauuacuac     1500

acaacgucaa cgcaggaaaa ucaacaacaa acaucaugau aacaacgaua auaauaguca     1560

uaauaguaau acuacuauca uuaaucgcag ucggacuccu auuauauugc aaagcuagau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3641
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3641
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuaaaagc caacgccaua accaccaucc      120

ucaccgcagu aacuuucugc uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa      180

guaccugcag cgcagucuca aaaggauacc uaggcgcccu acgcacaggc ugguacaccu      240

ccgucauuac caucgaacuc uccaacauca aagaaauuaa augcaacggu acagacgcaa      300

aagucaaacu caucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaccuccaac      360

uccucaugca auccaccccc gccacaggcu cuggcuccgc caucugcuca ggcguagcag      420

ucugcaaagu ccugcaccuc gaaggcgaag ucaacaaaau caagucagcc cuccucucca      480

ccaacaaggc cgucguaucc cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacuac uccccauccu aaacaaacaa ucaugcucca      600

ucccaaacau cgaaaccgua aucgaguucc aacaaaagaa caaccgccuc cucgaaauca      660

cacgugaguu cuccguuaac gccggcguca ccacccccgu cucuacauac augcucacca      720

acuccgaacu ccuuucccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguacaaauc guccgacaac aaagcuacuc caucaugugc aucaucaaag      840

aagaaguccu ugcauacguc guucaacuac cccucuacgg cguaaucgac acucccugcu      900

ggaaacucca caccuccccg cucugcacaa ccaacaccaa agaaggcagc aacaucugcc      960

ucacccgaac cgaccgcggc ugguacugcg auaacgccgg auccgucucc uucuucccac     1020

aagcagaaac uugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cacuccccuc cgaagucaac cugugcaacg ucgacaucuu caacccaaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacgucucau cuucugucau caccucucuc ggcgcuaucg     1200

ucuccugcua uggcaaaacc aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca auaagggcgu cgacaccguc ucugucggca     1320

acacccuuua cugcguaaac aaacaagaag gucaaucucu cuacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cuggucuucc ccuccgacga guucgaugca ucaaucuccc     1440

aagucaacga aaagaucaac caaucucucg cuuucauccg caaauccgac gaacuccuac     1500

acaacguaaa cgccggcaaa uccaccacaa acaucaugau caccaccauu aucauaguca     1560

ucaucgucau ccuccucucc uuaaucgccg uuggccuccu ucucuacugc aaagcccgau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3642
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3642
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3643
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3643
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3644
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3644
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3645
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3645
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3646
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3646
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3647
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3647
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3648
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3648
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ugaaagcaaa cgcaauuacu acaauacuaa cagcaguaac cuuuugcuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa cuugcucagc agucucaaaa      300

ggcuaucuag gagcacuacg aacagguugg uauacuucag ucauaacaau agaauuauca      360

aacauaaaag aaauuaaaug uaacggaacu gacgcaaaag uaaaacucau caaacaagaa      420

cucgauaaau acaaaaacgc uguaaccgac uuacaacuac uaaugcaauc aacuccagca      480

acaggcuccg gauccgcaau augcaguggu guagcaguau gcaaaguccu acaccuagaa      540

ggagaaguaa auaagauaaa aucugcucua cuaucaacaa auaaagcagu ugucucccua      600

ucaaauggag ucucaguacu caccuucaaa guauuagacc ucaaaaacua cauagacaaa      660

caacuauuac caauacucaa caaacaaucc ugcuccaucc cuaacauaga aaccguaauc      720

gaauuucaac aaaaaaauaa cagacucuua gaaauaacua gagaauuuuc aguuaaugca      780

ggcgugacaa caccaguauc aacauauaug cuaacaaacu ccgaacuccu aucccuaaua      840

aacgacaugc caaucacaaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaaucgua      900

agacaacaau cauacucuau aaugugcaua auaaaagaag aaguacuggc cuacguagua      960

caauuaccac ucuacggagu aauagacacc ccaugcugga aacuccauac aucaccccua     1020

ugcacaacaa acacaaaaga aggauccaac auaugucuca cuagaacaga cagaggcugg     1080

uacugcgaca acgcuggauc cgucucauuc uucccccaag cagaaacaug uaaaguacaa     1140

ucuaauagag uauuuuguga cacaaugaac agccucacac uaccauccga agucaaccua     1200

uguaacguag auauauuuaa ucccaaauac gacugcaaaa uaaugacauc caaaacagau     1260

guaucaucau ccguuaucac cucacuagga gccauaguuu caugcuacgg aaaaacaaaa     1320

ugcacugcau cuaacaaaaa uagagguaua auaaaaacau uuuccaacgg cugcgacuac     1380

gucucaaaca aaggcguaga caccguauca guaggaaaua cauuauauug cguaaauaaa     1440

caagaaggcc aaucccuaua cguaaaagga gaacccauca uaaacuucua ugacccacuu     1500

guuuuccccu cagacgaauu ugacgccuca auaucacaag uaaaugaaaa aauaaaccaa     1560

ucucuugccu ucauuagaaa aucagacgaa uuacuacaca acgucaacgc aggaaaauca     1620

acaacaaaca ucaugauaac aacgauaaua auagucauaa uaguaauacu acuaucauua     1680

aucgcagucg gacuccuauu auauugcaaa gcuagauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3649
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3649
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uaaaagccaa cgccauaacc accauccuca ccgcaguaac uuucugcuuc      240

gcuuccggcc aaaacaucac cgaagaauuu uaccaaagua ccugcagcgc agucucaaaa      300

ggauaccuag gcgcccuacg cacaggcugg uacaccuccg ucauuaccau cgaacucucc      360

aacaucaaag aaauuaaaug caacgguaca gacgcaaaag ucaaacucau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgac cuccaacucc ucaugcaauc cacccccgcc      480

acaggcucug gcuccgccau cugcucaggc guagcagucu gcaaaguccu gcaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cucuccacca acaaggccgu cguaucccuc      600

ucaaacggag uuagcguccu caccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuacucc ccauccuaaa caaacaauca ugcuccaucc caaacaucga aaccguaauc      720

gaguuccaac aaaagaacaa ccgccuccuc gaaaucacac gugaguucuc cguuaacgcc      780

ggcgucacca cccccgucuc uacauacaug cucaccaacu ccgaacuccu uucccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaaucguc      900

cgacaacaaa gcuacuccau caugugcauc aucaaagaag aaguccuugc auacgucguu      960

caacuacccc ucuacggcgu aaucgacacu cccugcugga aacuccacac cuccccgcuc     1020

ugcacaacca acaccaaaga aggcagcaac aucugccuca cccgaaccga ccgcggcugg     1080

uacugcgaua acgccggauc cgucuccuuc uucccacaag cagaaacuug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucacac uccccuccga agucaaccug     1200

ugcaacgucg acaucuucaa cccaaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

gucucaucuu cugucaucac cucucucggc gcuaucgucu ccugcuaugg caaaaccaaa     1320

ugcaccgccu ccaacaagaa ccgcggcauu aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaua agggcgucga caccgucucu gucggcaaca cccuuuacug cguaaacaaa     1440

caagaagguc aaucucucua cgucaaagga gaacccauca ucaacuucua cgacccccug     1500

gucuuccccu ccgacgaguu cgaugcauca aucucccaag ucaacgaaaa gaucaaccaa     1560

ucucucgcuu ucauccgcaa auccgacgaa cuccuacaca acguaaacgc cggcaaaucc     1620

accacaaaca ucaugaucac caccauuauc auagucauca ucgucauccu ccucuccuua     1680

aucgccguug gccuccuucu cuacugcaaa gcccgauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  3650
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3650
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3651
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3651
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      540

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1380

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1440

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3652
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3652
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3653
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3653
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      360

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      480

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      540

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      600

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      660

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      720

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      780

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      840

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua      900

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc      960

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg     1020

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1080

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1140

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1200

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1260

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1320

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1380

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1440

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1500

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1560

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1620

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3654
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3654
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3655
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3655
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      360

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      480

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      540

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      600

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      660

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      720

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      780

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      840

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug      900

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      960

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc     1020

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1080

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1140

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1200

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1260

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1320

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1380

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1440

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1500

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1560

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1620

cugauugccg uggggcuccu gcuguauugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3656
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3656
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaauuacuaa uccugaaagc aaacgcaauu acuacaauac uaacagcagu aaccuuuugc      180

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacuugcuc agcagucuca      240

aaaggcuauc uaggagcacu acgaacaggu ugguauacuu cagucauaac aauagaauua      300

ucaaacauaa aagaaauuaa auguaacgga acugacgcaa aaguaaaacu caucaaacaa      360

gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac uacuaaugca aucaacucca      420

gcaacaggcu ccggauccgc aauaugcagu gguguagcag uaugcaaagu ccuacaccua      480

gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa caaauaaagc aguugucucc      540

cuaucaaaug gagucucagu acucaccuuc aaaguauuag accucaaaaa cuacauagac      600

aaacaacuau uaccaauacu caacaaacaa uccugcucca ucccuaacau agaaaccgua      660

aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa cuagagaauu uucaguuaau      720

gcaggcguga caacaccagu aucaacauau augcuaacaa acuccgaacu ccuaucccua      780

auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa uguccaacaa cguacaaauc      840

guaagacaac aaucauacuc uauaaugugc auaauaaaag aagaaguacu ggccuacgua      900

guacaauuac cacucuacgg aguaauagac accccaugcu ggaaacucca uacaucaccc      960

cuaugcacaa caaacacaaa agaaggaucc aacauauguc ucacuagaac agacagaggc     1020

ugguacugcg acaacgcugg auccgucuca uucuuccccc aagcagaaac auguaaagua     1080

caaucuaaua gaguauuuug ugacacaaug aacagccuca cacuaccauc cgaagucaac     1140

cuauguaacg uagauauauu uaaucccaaa uacgacugca aaauaaugac auccaaaaca     1200

gauguaucau cauccguuau caccucacua ggagccauag uuucaugcua cggaaaaaca     1260

aaaugcacug caucuaacaa aaauagaggu auaauaaaaa cauuuuccaa cggcugcgac     1320

uacgucucaa acaaaggcgu agacaccgua ucaguaggaa auacauuaua uugcguaaau     1380

aaacaagaag gccaaucccu auacguaaaa ggagaaccca ucauaaacuu cuaugaccca     1440

cuuguuuucc ccucagacga auuugacgcc ucaauaucac aaguaaauga aaaaauaaac     1500

caaucucuug ccuucauuag aaaaucagac gaauuacuac acaacgucaa cgcaggaaaa     1560

ucaacaacaa acaucaugau aacaacgaua auaauaguca uaauaguaau acuacuauca     1620

uuaaucgcag ucggacuccu auuauauugc aaagcuagau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3657
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3657
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuca uacuaaaagc caacgccaua accaccaucc ucaccgcagu aacuuucugc      180

uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa guaccugcag cgcagucuca      240

aaaggauacc uaggcgcccu acgcacaggc ugguacaccu ccgucauuac caucgaacuc      300

uccaacauca aagaaauuaa augcaacggu acagacgcaa aagucaaacu caucaaacaa      360

gaacucgaca aauacaaaaa cgcagucacc gaccuccaac uccucaugca auccaccccc      420

gccacaggcu cuggcuccgc caucugcuca ggcguagcag ucugcaaagu ccugcaccuc      480

gaaggcgaag ucaacaaaau caagucagcc cuccucucca ccaacaaggc cgucguaucc      540

cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag accucaaaaa cuacaucgau      600

aaacaacuac uccccauccu aaacaaacaa ucaugcucca ucccaaacau cgaaaccgua      660

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cacgugaguu cuccguuaac      720

gccggcguca ccacccccgu cucuacauac augcucacca acuccgaacu ccuuucccuc      780

aucaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguacaaauc      840

guccgacaac aaagcuacuc caucaugugc aucaucaaag aagaaguccu ugcauacguc      900

guucaacuac cccucuacgg cguaaucgac acucccugcu ggaaacucca caccuccccg      960

cucugcacaa ccaacaccaa agaaggcagc aacaucugcc ucacccgaac cgaccgcggc     1020

ugguacugcg auaacgccgg auccgucucc uucuucccac aagcagaaac uugcaaaguc     1080

caauccaacc gcgucuucug cgacaccaug aacucccuca cacuccccuc cgaagucaac     1140

cugugcaacg ucgacaucuu caacccaaaa uacgacugca aaaucaugac cucaaaaacc     1200

gacgucucau cuucugucau caccucucuc ggcgcuaucg ucuccugcua uggcaaaacc     1260

aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca auaagggcgu cgacaccguc ucugucggca acacccuuua cugcguaaac     1380

aaacaagaag gucaaucucu cuacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1440

cuggucuucc ccuccgacga guucgaugca ucaaucuccc aagucaacga aaagaucaac     1500

caaucucucg cuuucauccg caaauccgac gaacuccuac acaacguaaa cgccggcaaa     1560

uccaccacaa acaucaugau caccaccauu aucauaguca ucaucgucau ccuccucucc     1620

uuaaucgccg uuggccuccu ucucuacugc aaagcccgau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  3658
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3658
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3659
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3659
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3660
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3660
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3661
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3661
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3662
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3662
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3663
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3663
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3664
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3664
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccugaaa      120

gcaaacgcaa uuacuacaau acuaacagca guaaccuuuu gcuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacuugc ucagcagucu caaaaggcua ucuaggagca      240

cuacgaacag guugguauac uucagucaua acaauagaau uaucaaacau aaaagaaauu      300

aaauguaacg gaacugacgc aaaaguaaaa cucaucaaac aagaacucga uaaauacaaa      360

aacgcuguaa ccgacuuaca acuacuaaug caaucaacuc cagcaacagg cuccggaucc      420

gcaauaugca gugguguagc aguaugcaaa guccuacacc uagaaggaga aguaaauaag      480

auaaaaucug cucuacuauc aacaaauaaa gcaguugucu cccuaucaaa uggagucuca      540

guacucaccu ucaaaguauu agaccucaaa aacuacauag acaaacaacu auuaccaaua      600

cucaacaaac aauccugcuc caucccuaac auagaaaccg uaaucgaauu ucaacaaaaa      660

aauaacagac ucuuagaaau aacuagagaa uuuucaguua augcaggcgu gacaacacca      720

guaucaacau auaugcuaac aaacuccgaa cuccuauccc uaauaaacga caugccaauc      780

acaaacgacc aaaaaaaacu aauguccaac aacguacaaa ucguaagaca acaaucauac      840

ucuauaaugu gcauaauaaa agaagaagua cuggccuacg uaguacaauu accacucuac      900

ggaguaauag acaccccaug cuggaaacuc cauacaucac cccuaugcac aacaaacaca      960

aaagaaggau ccaacauaug ucucacuaga acagacagag gcugguacug cgacaacgcu     1020

ggauccgucu cauucuuccc ccaagcagaa acauguaaag uacaaucuaa uagaguauuu     1080

ugugacacaa ugaacagccu cacacuacca uccgaaguca accuauguaa cguagauaua     1140

uuuaauccca aauacgacug caaaauaaug acauccaaaa cagauguauc aucauccguu     1200

aucaccucac uaggagccau aguuucaugc uacggaaaaa caaaaugcac ugcaucuaac     1260

aaaaauagag guauaauaaa aacauuuucc aacggcugcg acuacgucuc aaacaaaggc     1320

guagacaccg uaucaguagg aaauacauua uauugcguaa auaaacaaga aggccaaucc     1380

cuauacguaa aaggagaacc caucauaaac uucuaugacc cacuuguuuu ccccucagac     1440

gaauuugacg ccucaauauc acaaguaaau gaaaaaauaa accaaucucu ugccuucauu     1500

agaaaaucag acgaauuacu acacaacguc aacgcaggaa aaucaacaac aaacaucaug     1560

auaacaacga uaauaauagu cauaauagua auacuacuau cauuaaucgc agucggacuc     1620

cuauuauauu gcaaagcuag auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3665
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3665
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuaaaa      120

gccaacgcca uaaccaccau ccucaccgca guaacuuucu gcuucgcuuc cggccaaaac      180

aucaccgaag aauuuuacca aaguaccugc agcgcagucu caaaaggaua ccuaggcgcc      240

cuacgcacag gcugguacac cuccgucauu accaucgaac ucuccaacau caaagaaauu      300

aaaugcaacg guacagacgc aaaagucaaa cucaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaccucca acuccucaug caauccaccc ccgccacagg cucuggcucc      420

gccaucugcu caggcguagc agucugcaaa guccugcacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccucuc caccaacaag gccgucguau cccucucaaa cggaguuagc      540

guccucaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu acuccccauc      600

cuaaacaaac aaucaugcuc caucccaaac aucgaaaccg uaaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacacgugag uucuccguua acgccggcgu caccaccccc      720

gucucuacau acaugcucac caacuccgaa cuccuuuccc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguacaaa ucguccgaca acaaagcuac      840

uccaucaugu gcaucaucaa agaagaaguc cuugcauacg ucguucaacu accccucuac      900

ggcguaaucg acacucccug cuggaaacuc cacaccuccc cgcucugcac aaccaacacc      960

aaagaaggca gcaacaucug ccucacccga accgaccgcg gcugguacug cgauaacgcc     1020

ggauccgucu ccuucuuccc acaagcagaa acuugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacacucccc uccgaaguca accugugcaa cgucgacauc     1140

uucaacccaa aauacgacug caaaaucaug accucaaaaa ccgacgucuc aucuucuguc     1200

aucaccucuc ucggcgcuau cgucuccugc uauggcaaaa ccaaaugcac cgccuccaac     1260

aagaaccgcg gcauuaucaa gaccuucucc aacggcugcg acuacgucuc caauaagggc     1320

gucgacaccg ucucugucgg caacacccuu uacugcguaa acaaacaaga aggucaaucu     1380

cucuacguca aaggagaacc caucaucaac uucuacgacc cccuggucuu ccccuccgac     1440

gaguucgaug caucaaucuc ccaagucaac gaaaagauca accaaucucu cgcuuucauc     1500

cgcaaauccg acgaacuccu acacaacgua aacgccggca aauccaccac aaacaucaug     1560

aucaccacca uuaucauagu caucaucguc auccuccucu ccuuaaucgc cguuggccuc     1620

cuucucuacu gcaaagcccg auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  3666
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3666
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3667
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3667
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3668
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3668
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3669
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3669
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3670
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3670
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3671
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3671
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3672
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3672
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccugaaa gcaaacgcaa uuacuacaau acuaacagca      120

guaaccuuuu gcuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacuugc      180

ucagcagucu caaaaggcua ucuaggagca cuacgaacag guugguauac uucagucaua      240

acaauagaau uaucaaacau aaaagaaauu aaauguaacg gaacugacgc aaaaguaaaa      300

cucaucaaac aagaacucga uaaauacaaa aacgcuguaa ccgacuuaca acuacuaaug      360

caaucaacuc cagcaacagg cuccggaucc gcaauaugca gugguguagc aguaugcaaa      420

guccuacacc uagaaggaga aguaaauaag auaaaaucug cucuacuauc aacaaauaaa      480

gcaguugucu cccuaucaaa uggagucuca guacucaccu ucaaaguauu agaccucaaa      540

aacuacauag acaaacaacu auuaccaaua cucaacaaac aauccugcuc caucccuaac      600

auagaaaccg uaaucgaauu ucaacaaaaa aauaacagac ucuuagaaau aacuagagaa      660

uuuucaguua augcaggcgu gacaacacca guaucaacau auaugcuaac aaacuccgaa      720

cuccuauccc uaauaaacga caugccaauc acaaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa ucguaagaca acaaucauac ucuauaaugu gcauaauaaa agaagaagua      840

cuggccuacg uaguacaauu accacucuac ggaguaauag acaccccaug cuggaaacuc      900

cauacaucac cccuaugcac aacaaacaca aaagaaggau ccaacauaug ucucacuaga      960

acagacagag gcugguacug cgacaacgcu ggauccgucu cauucuuccc ccaagcagaa     1020

acauguaaag uacaaucuaa uagaguauuu ugugacacaa ugaacagccu cacacuacca     1080

uccgaaguca accuauguaa cguagauaua uuuaauccca aauacgacug caaaauaaug     1140

acauccaaaa cagauguauc aucauccguu aucaccucac uaggagccau aguuucaugc     1200

uacggaaaaa caaaaugcac ugcaucuaac aaaaauagag guauaauaaa aacauuuucc     1260

aacggcugcg acuacgucuc aaacaaaggc guagacaccg uaucaguagg aaauacauua     1320

uauugcguaa auaaacaaga aggccaaucc cuauacguaa aaggagaacc caucauaaac     1380

uucuaugacc cacuuguuuu ccccucagac gaauuugacg ccucaauauc acaaguaaau     1440

gaaaaaauaa accaaucucu ugccuucauu agaaaaucag acgaauuacu acacaacguc     1500

aacgcaggaa aaucaacaac aaacaucaug auaacaacga uaauaauagu cauaauagua     1560

auacuacuau cauuaaucgc agucggacuc cuauuauauu gcaaagcuag auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3673
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3673
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuaaaa gccaacgcca uaaccaccau ccucaccgca      120

guaacuuucu gcuucgcuuc cggccaaaac aucaccgaag aauuuuacca aaguaccugc      180

agcgcagucu caaaaggaua ccuaggcgcc cuacgcacag gcugguacac cuccgucauu      240

accaucgaac ucuccaacau caaagaaauu aaaugcaacg guacagacgc aaaagucaaa      300

cucaucaaac aagaacucga caaauacaaa aacgcaguca ccgaccucca acuccucaug      360

caauccaccc ccgccacagg cucuggcucc gccaucugcu caggcguagc agucugcaaa      420

guccugcacc ucgaaggcga agucaacaaa aucaagucag cccuccucuc caccaacaag      480

gccgucguau cccucucaaa cggaguuagc guccucaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu acuccccauc cuaaacaaac aaucaugcuc caucccaaac      600

aucgaaaccg uaaucgaguu ccaacaaaag aacaaccgcc uccucgaaau cacacgugag      660

uucuccguua acgccggcgu caccaccccc gucucuacau acaugcucac caacuccgaa      720

cuccuuuccc ucaucaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguacaaa ucguccgaca acaaagcuac uccaucaugu gcaucaucaa agaagaaguc      840

cuugcauacg ucguucaacu accccucuac ggcguaaucg acacucccug cuggaaacuc      900

cacaccuccc cgcucugcac aaccaacacc aaagaaggca gcaacaucug ccucacccga      960

accgaccgcg gcugguacug cgauaacgcc ggauccgucu ccuucuuccc acaagcagaa     1020

acuugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacacucccc     1080

uccgaaguca accugugcaa cgucgacauc uucaacccaa aauacgacug caaaaucaug     1140

accucaaaaa ccgacgucuc aucuucuguc aucaccucuc ucggcgcuau cgucuccugc     1200

uauggcaaaa ccaaaugcac cgccuccaac aagaaccgcg gcauuaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caauaagggc gucgacaccg ucucugucgg caacacccuu     1320

uacugcguaa acaaacaaga aggucaaucu cucuacguca aaggagaacc caucaucaac     1380

uucuacgacc cccuggucuu ccccuccgac gaguucgaug caucaaucuc ccaagucaac     1440

gaaaagauca accaaucucu cgcuuucauc cgcaaauccg acgaacuccu acacaacgua     1500

aacgccggca aauccaccac aaacaucaug aucaccacca uuaucauagu caucaucguc     1560

auccuccucu ccuuaaucgc cguuggccuc cuucucuacu gcaaagcccg auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  3674
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3674
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3675
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3675
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3676
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3676
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3677
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3677
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3678
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3678
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3679
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3679
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3680
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3680
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu gaaagcaaac gcaauuacua caauacuaac agcaguaacc      180

uuuugcuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac uugcucagca      240

gucucaaaag gcuaucuagg agcacuacga acagguuggu auacuucagu cauaacaaua      300

gaauuaucaa acauaaaaga aauuaaaugu aacggaacug acgcaaaagu aaaacucauc      360

aaacaagaac ucgauaaaua caaaaacgcu guaaccgacu uacaacuacu aaugcaauca      420

acuccagcaa caggcuccgg auccgcaaua ugcaguggug uagcaguaug caaaguccua      480

caccuagaag gagaaguaaa uaagauaaaa ucugcucuac uaucaacaaa uaaagcaguu      540

gucucccuau caaauggagu cucaguacuc accuucaaag uauuagaccu caaaaacuac      600

auagacaaac aacuauuacc aauacucaac aaacaauccu gcuccauccc uaacauagaa      660

accguaaucg aauuucaaca aaaaaauaac agacucuuag aaauaacuag agaauuuuca      720

guuaaugcag gcgugacaac accaguauca acauauaugc uaacaaacuc cgaacuccua      780

ucccuaauaa acgacaugcc aaucacaaac gaccaaaaaa aacuaauguc caacaacgua      840

caaaucguaa gacaacaauc auacucuaua augugcauaa uaaaagaaga aguacuggcc      900

uacguaguac aauuaccacu cuacggagua auagacaccc caugcuggaa acuccauaca      960

ucaccccuau gcacaacaaa cacaaaagaa ggauccaaca uaugucucac uagaacagac     1020

agaggcuggu acugcgacaa cgcuggaucc gucucauucu ucccccaagc agaaacaugu     1080

aaaguacaau cuaauagagu auuuugugac acaaugaaca gccucacacu accauccgaa     1140

gucaaccuau guaacguaga uauauuuaau cccaaauacg acugcaaaau aaugacaucc     1200

aaaacagaug uaucaucauc cguuaucacc ucacuaggag ccauaguuuc augcuacgga     1260

aaaacaaaau gcacugcauc uaacaaaaau agagguauaa uaaaaacauu uuccaacggc     1320

ugcgacuacg ucucaaacaa aggcguagac accguaucag uaggaaauac auuauauugc     1380

guaaauaaac aagaaggcca aucccuauac guaaaaggag aacccaucau aaacuucuau     1440

gacccacuug uuuuccccuc agacgaauuu gacgccucaa uaucacaagu aaaugaaaaa     1500

auaaaccaau cucuugccuu cauuagaaaa ucagacgaau uacuacacaa cgucaacgca     1560

ggaaaaucaa caacaaacau caugauaaca acgauaauaa uagucauaau aguaauacua     1620

cuaucauuaa ucgcagucgg acuccuauua uauugcaaag cuagauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3681
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3681
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu aaaagccaac gccauaacca ccauccucac cgcaguaacu      180

uucugcuucg cuuccggcca aaacaucacc gaagaauuuu accaaaguac cugcagcgca      240

gucucaaaag gauaccuagg cgcccuacgc acaggcuggu acaccuccgu cauuaccauc      300

gaacucucca acaucaaaga aauuaaaugc aacgguacag acgcaaaagu caaacucauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgacc uccaacuccu caugcaaucc      420

acccccgcca caggcucugg cuccgccauc ugcucaggcg uagcagucug caaaguccug      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc ucuccaccaa caaggccguc      540

guaucccucu caaacggagu uagcguccuc accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuacuccc cauccuaaac aaacaaucau gcuccauccc aaacaucgaa      660

accguaaucg aguuccaaca aaagaacaac cgccuccucg aaaucacacg ugaguucucc      720

guuaacgccg gcgucaccac ccccgucucu acauacaugc ucaccaacuc cgaacuccuu      780

ucccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacgua      840

caaaucgucc gacaacaaag cuacuccauc augugcauca ucaaagaaga aguccuugca      900

uacgucguuc aacuaccccu cuacggcgua aucgacacuc ccugcuggaa acuccacacc      960

uccccgcucu gcacaaccaa caccaaagaa ggcagcaaca ucugccucac ccgaaccgac     1020

cgcggcuggu acugcgauaa cgccggaucc gucuccuucu ucccacaagc agaaacuugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacacu ccccuccgaa     1140

gucaaccugu gcaacgucga caucuucaac ccaaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg ucucaucuuc ugucaucacc ucucucggcg cuaucgucuc cugcuauggc     1260

aaaaccaaau gcaccgccuc caacaagaac cgcggcauua ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaauaa gggcgucgac accgucucug ucggcaacac ccuuuacugc     1380

guaaacaaac aagaagguca aucucucuac gucaaaggag aacccaucau caacuucuac     1440

gacccccugg ucuuccccuc cgacgaguuc gaugcaucaa ucucccaagu caacgaaaag     1500

aucaaccaau cucucgcuuu cauccgcaaa uccgacgaac uccuacacaa cguaaacgcc     1560

ggcaaaucca ccacaaacau caugaucacc accauuauca uagucaucau cgucauccuc     1620

cucuccuuaa ucgccguugg ccuccuucuc uacugcaaag cccgauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  3682
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3682
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3683
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3683
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3684
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3684
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3685
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3685
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3686
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3686
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3687
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3687
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3688
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3688
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccugaa agcaaacgca      120

auuacuacaa uacuaacagc aguaaccuuu ugcuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacuug cucagcaguc ucaaaaggcu aucuaggagc acuacgaaca      240

gguugguaua cuucagucau aacaauagaa uuaucaaaca uaaaagaaau uaaauguaac      300

ggaacugacg caaaaguaaa acucaucaaa caagaacucg auaaauacaa aaacgcugua      360

accgacuuac aacuacuaau gcaaucaacu ccagcaacag gcuccggauc cgcaauaugc      420

agugguguag caguaugcaa aguccuacac cuagaaggag aaguaaauaa gauaaaaucu      480

gcucuacuau caacaaauaa agcaguuguc ucccuaucaa auggagucuc aguacucacc      540

uucaaaguau uagaccucaa aaacuacaua gacaaacaac uauuaccaau acucaacaaa      600

caauccugcu ccaucccuaa cauagaaacc guaaucgaau uucaacaaaa aaauaacaga      660

cucuuagaaa uaacuagaga auuuucaguu aaugcaggcg ugacaacacc aguaucaaca      720

uauaugcuaa caaacuccga acuccuaucc cuaauaaacg acaugccaau cacaaacgac      780

caaaaaaaac uaauguccaa caacguacaa aucguaagac aacaaucaua cucuauaaug      840

ugcauaauaa aagaagaagu acuggccuac guaguacaau uaccacucua cggaguaaua      900

gacaccccau gcuggaaacu ccauacauca ccccuaugca caacaaacac aaaagaagga      960

uccaacauau gucucacuag aacagacaga ggcugguacu gcgacaacgc uggauccguc     1020

ucauucuucc cccaagcaga aacauguaaa guacaaucua auagaguauu uugugacaca     1080

augaacagcc ucacacuacc auccgaaguc aaccuaugua acguagauau auuuaauccc     1140

aaauacgacu gcaaaauaau gacauccaaa acagauguau caucauccgu uaucaccuca     1200

cuaggagcca uaguuucaug cuacggaaaa acaaaaugca cugcaucuaa caaaaauaga     1260

gguauaauaa aaacauuuuc caacggcugc gacuacgucu caaacaaagg cguagacacc     1320

guaucaguag gaaauacauu auauugcgua aauaaacaag aaggccaauc ccuauacgua     1380

aaaggagaac ccaucauaaa cuucuaugac ccacuuguuu uccccucaga cgaauuugac     1440

gccucaauau cacaaguaaa ugaaaaaaua aaccaaucuc uugccuucau uagaaaauca     1500

gacgaauuac uacacaacgu caacgcagga aaaucaacaa caaacaucau gauaacaacg     1560

auaauaauag ucauaauagu aauacuacua ucauuaaucg cagucggacu ccuauuauau     1620

ugcaaagcua gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3689
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3689
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuaaa agccaacgcc      120

auaaccacca uccucaccgc aguaacuuuc ugcuucgcuu ccggccaaaa caucaccgaa      180

gaauuuuacc aaaguaccug cagcgcaguc ucaaaaggau accuaggcgc ccuacgcaca      240

ggcugguaca ccuccgucau uaccaucgaa cucuccaaca ucaaagaaau uaaaugcaac      300

gguacagacg caaaagucaa acucaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaccucc aacuccucau gcaauccacc cccgccacag gcucuggcuc cgccaucugc      420

ucaggcguag cagucugcaa aguccugcac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccucu ccaccaacaa ggccgucgua ucccucucaa acggaguuag cguccucacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uacuccccau ccuaaacaaa      600

caaucaugcu ccaucccaaa caucgaaacc guaaucgagu uccaacaaaa gaacaaccgc      660

cuccucgaaa ucacacguga guucuccguu aacgccggcg ucaccacccc cgucucuaca      720

uacaugcuca ccaacuccga acuccuuucc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguacaa aucguccgac aacaaagcua cuccaucaug      840

ugcaucauca aagaagaagu ccuugcauac gucguucaac uaccccucua cggcguaauc      900

gacacucccu gcuggaaacu ccacaccucc ccgcucugca caaccaacac caaagaaggc      960

agcaacaucu gccucacccg aaccgaccgc ggcugguacu gcgauaacgc cggauccguc     1020

uccuucuucc cacaagcaga aacuugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacacuccc cuccgaaguc aaccugugca acgucgacau cuucaaccca     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacgucu caucuucugu caucaccucu     1200

cucggcgcua ucgucuccug cuauggcaaa accaaaugca ccgccuccaa caagaaccgc     1260

ggcauuauca agaccuucuc caacggcugc gacuacgucu ccaauaaggg cgucgacacc     1320

gucucugucg gcaacacccu uuacugcgua aacaaacaag aaggucaauc ucucuacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccuggucu uccccuccga cgaguucgau     1440

gcaucaaucu cccaagucaa cgaaaagauc aaccaaucuc ucgcuuucau ccgcaaaucc     1500

gacgaacucc uacacaacgu aaacgccggc aaauccacca caaacaucau gaucaccacc     1560

auuaucauag ucaucaucgu cauccuccuc uccuuaaucg ccguuggccu ccuucucuac     1620

ugcaaagccc gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  3690
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3690
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3691
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3691
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3692
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3692
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3693
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3693
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3694
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3694
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3695
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3695
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3696
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3696
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccugaa agcaaacgca      120

auuacuacaa uacuaacagc aguaaccuuu ugcuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacuug cucagcaguc ucaaaaggcu aucuaggagc acuacgaaca      240

gguugguaua cuucagucau aacaauagaa uuaucaaaca uaaaagaaau uaaauguaac      300

ggaacugacg caaaaguaaa acucaucaaa caagaacucg auaaauacaa aaacgcugua      360

accgacuuac aacuacuaau gcaaucaacu ccagcaacag gcuccggauc cgcaauaugc      420

agugguguag caguaugcaa aguccuacac cuagaaggag aaguaaauaa gauaaaaucu      480

gcucuacuau caacaaauaa agcaguuguc ucccuaucaa auggagucuc aguacucacc      540

uucaaaguau uagaccucaa aaacuacaua gacaaacaac uauuaccaau acucaacaaa      600

caauccugcu ccaucccuaa cauagaaacc guaaucgaau uucaacaaaa aaauaacaga      660

cucuuagaaa uaacuagaga auuuucaguu aaugcaggcg ugacaacacc aguaucaaca      720

uauaugcuaa caaacuccga acuccuaucc cuaauaaacg acaugccaau cacaaacgac      780

caaaaaaaac uaauguccaa caacguacaa aucguaagac aacaaucaua cucuauaaug      840

ugcauaauaa aagaagaagu acuggccuac guaguacaau uaccacucua cggaguaaua      900

gacaccccau gcuggaaacu ccauacauca ccccuaugca caacaaacac aaaagaagga      960

uccaacauau gucucacuag aacagacaga ggcugguacu gcgacaacgc uggauccguc     1020

ucauucuucc cccaagcaga aacauguaaa guacaaucua auagaguauu uugugacaca     1080

augaacagcc ucacacuacc auccgaaguc aaccuaugua acguagauau auuuaauccc     1140

aaauacgacu gcaaaauaau gacauccaaa acagauguau caucauccgu uaucaccuca     1200

cuaggagcca uaguuucaug cuacggaaaa acaaaaugca cugcaucuaa caaaaauaga     1260

gguauaauaa aaacauuuuc caacggcugc gacuacgucu caaacaaagg cguagacacc     1320

guaucaguag gaaauacauu auauugcgua aauaaacaag aaggccaauc ccuauacgua     1380

aaaggagaac ccaucauaaa cuucuaugac ccacuuguuu uccccucaga cgaauuugac     1440

gccucaauau cacaaguaaa ugaaaaaaua aaccaaucuc uugccuucau uagaaaauca     1500

gacgaauuac uacacaacgu caacgcagga aaaucaacaa caaacaucau gauaacaacg     1560

auaauaauag ucauaauagu aauacuacua ucauuaaucg cagucggacu ccuauuauau     1620

ugcaaagcua gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3697
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3697
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuaaa agccaacgcc      120

auaaccacca uccucaccgc aguaacuuuc ugcuucgcuu ccggccaaaa caucaccgaa      180

gaauuuuacc aaaguaccug cagcgcaguc ucaaaaggau accuaggcgc ccuacgcaca      240

ggcugguaca ccuccgucau uaccaucgaa cucuccaaca ucaaagaaau uaaaugcaac      300

gguacagacg caaaagucaa acucaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaccucc aacuccucau gcaauccacc cccgccacag gcucuggcuc cgccaucugc      420

ucaggcguag cagucugcaa aguccugcac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccucu ccaccaacaa ggccgucgua ucccucucaa acggaguuag cguccucacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uacuccccau ccuaaacaaa      600

caaucaugcu ccaucccaaa caucgaaacc guaaucgagu uccaacaaaa gaacaaccgc      660

cuccucgaaa ucacacguga guucuccguu aacgccggcg ucaccacccc cgucucuaca      720

uacaugcuca ccaacuccga acuccuuucc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguacaa aucguccgac aacaaagcua cuccaucaug      840

ugcaucauca aagaagaagu ccuugcauac gucguucaac uaccccucua cggcguaauc      900

gacacucccu gcuggaaacu ccacaccucc ccgcucugca caaccaacac caaagaaggc      960

agcaacaucu gccucacccg aaccgaccgc ggcugguacu gcgauaacgc cggauccguc     1020

uccuucuucc cacaagcaga aacuugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacacuccc cuccgaaguc aaccugugca acgucgacau cuucaaccca     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacgucu caucuucugu caucaccucu     1200

cucggcgcua ucgucuccug cuauggcaaa accaaaugca ccgccuccaa caagaaccgc     1260

ggcauuauca agaccuucuc caacggcugc gacuacgucu ccaauaaggg cgucgacacc     1320

gucucugucg gcaacacccu uuacugcgua aacaaacaag aaggucaauc ucucuacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccuggucu uccccuccga cgaguucgau     1440

gcaucaaucu cccaagucaa cgaaaagauc aaccaaucuc ucgcuuucau ccgcaaaucc     1500

gacgaacucc uacacaacgu aaacgccggc aaauccacca caaacaucau gaucaccacc     1560

auuaucauag ucaucaucgu cauccuccuc uccuuaaucg ccguuggccu ccuucucuac     1620

ugcaaagccc gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  3698
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3698
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3699
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3699
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3700
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3700
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3701
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3701
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3702
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3702
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3703
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3703
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3704
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3704
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccugaa agcaaacgca      120

auuacuacaa uacuaacagc aguaaccuuu ugcuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacuug cucagcaguc ucaaaaggcu aucuaggagc acuacgaaca      240

gguugguaua cuucagucau aacaauagaa uuaucaaaca uaaaagaaau uaaauguaac      300

ggaacugacg caaaaguaaa acucaucaaa caagaacucg auaaauacaa aaacgcugua      360

accgacuuac aacuacuaau gcaaucaacu ccagcaacag gcuccggauc cgcaauaugc      420

agugguguag caguaugcaa aguccuacac cuagaaggag aaguaaauaa gauaaaaucu      480

gcucuacuau caacaaauaa agcaguuguc ucccuaucaa auggagucuc aguacucacc      540

uucaaaguau uagaccucaa aaacuacaua gacaaacaac uauuaccaau acucaacaaa      600

caauccugcu ccaucccuaa cauagaaacc guaaucgaau uucaacaaaa aaauaacaga      660

cucuuagaaa uaacuagaga auuuucaguu aaugcaggcg ugacaacacc aguaucaaca      720

uauaugcuaa caaacuccga acuccuaucc cuaauaaacg acaugccaau cacaaacgac      780

caaaaaaaac uaauguccaa caacguacaa aucguaagac aacaaucaua cucuauaaug      840

ugcauaauaa aagaagaagu acuggccuac guaguacaau uaccacucua cggaguaaua      900

gacaccccau gcuggaaacu ccauacauca ccccuaugca caacaaacac aaaagaagga      960

uccaacauau gucucacuag aacagacaga ggcugguacu gcgacaacgc uggauccguc     1020

ucauucuucc cccaagcaga aacauguaaa guacaaucua auagaguauu uugugacaca     1080

augaacagcc ucacacuacc auccgaaguc aaccuaugua acguagauau auuuaauccc     1140

aaauacgacu gcaaaauaau gacauccaaa acagauguau caucauccgu uaucaccuca     1200

cuaggagcca uaguuucaug cuacggaaaa acaaaaugca cugcaucuaa caaaaauaga     1260

gguauaauaa aaacauuuuc caacggcugc gacuacgucu caaacaaagg cguagacacc     1320

guaucaguag gaaauacauu auauugcgua aauaaacaag aaggccaauc ccuauacgua     1380

aaaggagaac ccaucauaaa cuucuaugac ccacuuguuu uccccucaga cgaauuugac     1440

gccucaauau cacaaguaaa ugaaaaaaua aaccaaucuc uugccuucau uagaaaauca     1500

gacgaauuac uacacaacgu caacgcagga aaaucaacaa caaacaucau gauaacaacg     1560

auaauaauag ucauaauagu aauacuacua ucauuaaucg cagucggacu ccuauuauau     1620

ugcaaagcua gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3705
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3705
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuaaa agccaacgcc      120

auaaccacca uccucaccgc aguaacuuuc ugcuucgcuu ccggccaaaa caucaccgaa      180

gaauuuuacc aaaguaccug cagcgcaguc ucaaaaggau accuaggcgc ccuacgcaca      240

ggcugguaca ccuccgucau uaccaucgaa cucuccaaca ucaaagaaau uaaaugcaac      300

gguacagacg caaaagucaa acucaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaccucc aacuccucau gcaauccacc cccgccacag gcucuggcuc cgccaucugc      420

ucaggcguag cagucugcaa aguccugcac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccucu ccaccaacaa ggccgucgua ucccucucaa acggaguuag cguccucacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uacuccccau ccuaaacaaa      600

caaucaugcu ccaucccaaa caucgaaacc guaaucgagu uccaacaaaa gaacaaccgc      660

cuccucgaaa ucacacguga guucuccguu aacgccggcg ucaccacccc cgucucuaca      720

uacaugcuca ccaacuccga acuccuuucc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguacaa aucguccgac aacaaagcua cuccaucaug      840

ugcaucauca aagaagaagu ccuugcauac gucguucaac uaccccucua cggcguaauc      900

gacacucccu gcuggaaacu ccacaccucc ccgcucugca caaccaacac caaagaaggc      960

agcaacaucu gccucacccg aaccgaccgc ggcugguacu gcgauaacgc cggauccguc     1020

uccuucuucc cacaagcaga aacuugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacacuccc cuccgaaguc aaccugugca acgucgacau cuucaaccca     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacgucu caucuucugu caucaccucu     1200

cucggcgcua ucgucuccug cuauggcaaa accaaaugca ccgccuccaa caagaaccgc     1260

ggcauuauca agaccuucuc caacggcugc gacuacgucu ccaauaaggg cgucgacacc     1320

gucucugucg gcaacacccu uuacugcgua aacaaacaag aaggucaauc ucucuacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccuggucu uccccuccga cgaguucgau     1440

gcaucaaucu cccaagucaa cgaaaagauc aaccaaucuc ucgcuuucau ccgcaaaucc     1500

gacgaacucc uacacaacgu aaacgccggc aaauccacca caaacaucau gaucaccacc     1560

auuaucauag ucaucaucgu cauccuccuc uccuuaaucg ccguuggccu ccuucucuac     1620

ugcaaagccc gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  3706
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3706
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3707
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3707
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucugc      420

uccggcgugg ccgugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcgcugcugu ccaccaacaa ggccgugguc agccucucca acggcgugag cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

caguccugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccgcugua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg      960

uccaacaucu gccugacccg caccgaccgg ggcugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu cuacugcguc aacaagcagg agggccagag ccuguacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3708
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3708
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3709
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3709
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucugu      420

ucaggcgugg cagucugcaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcccugcuga guacgaacaa agcugugguc ucccucucua auggggugag cguauuaacu      540

uuuaagguuc uggaucuuaa gaacuacauc gacaaacaau ugcugccuau ucuaaauaag      600

caguccuguu caaucccaaa cauagaaacc gugauugagu uccagcagaa aaauaacagg      660

cuccuggaaa ucacacggga guuuaguguc aaugccggag ugacuacccc ggugagcaca      720

uauaugcuua ccaacucuga gcuguugucc cucauuaaug auaugcccau cacgaacgac      780

caaaagaaac ugaugucaaa caauguccag aucguucgcc agcagagcua caguauuaug      840

ugcauaauca aggaagaggu guuagcguau guagugcaac ugccucucua cggcgucauu      900

gauacuccau guuggaaacu ucauacaucu ccccugugca ccacuaacac aaaggaaggc      960

uccaauaucu guuugacccg aacggaccgu gggugguacu gcgauaacgc aggaagcgug     1020

ucguucuuuc cucaggccga gaccuguaag guucagucua auagaguguu cugcgacaca     1080

augaacuccc uaacucugcc aucagaaguc aaucucugca acguggauau auuuaauccc     1140

aaauaugacu guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cugggugcua ucgugucaug cuacggcaag accaaaugua cagccaguaa caagaauagg     1260

gggauuauca agaccuucuc caacggaugc gacuauguca gcaauaaagg cguggacacu     1320

gucucugugg guaacacgcu uuacuguguu aauaagcaag aggggcaguc acuguaugug     1380

aaaggagagc cuauuauaaa cuuuuacgau ccauugguau ucccgaguga cgaauuugau     1440

gcaagcaucu cccaggucaa cgagaagauu aaucagucuc ucgcuuucau ccggaaaucg     1500

gacgaacugu uacacaacgu gaaugccggc aagagcacaa ccaacaucau gauuacuacc     1560

auaaucauug uuaucauugu gauccugcua ucccucauag cggucggccu gcuuuuguau     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3710
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3710
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3711
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3711
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucugu      420

agcggggucg ccgugugcaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcgcuucuga gcaccaacaa agccgucgug ucucucucca auggcguuag cgugcugaca      540

uuuaaggucc uugaucugaa gaacuacauc gacaaacaac uccugccuau ucugaauaag      600

cagucuuguu ccaucccgaa cauugaaacc gugaucgagu uccagcagaa aaauaaccgg      660

cuccuggaaa ucacgcgcga guuuagcgug aaugcuggcg ucacaacccc cguuucuaca      720

uauaugcuua ccaacuccga gcugcucagc cugauuaaug auaugccuau caccaacgac      780

caaaagaaac uuauguccaa caaugugcag auugugagac agcagucuua cagcaucaug      840

ugcauuauca aggaagaggu ccuggccuau gugguucaac ucccccugua cggggugauc      900

gauacaccuu guuggaaacu gcauacgagc ccccucugca ccacaaacac caaggaagga      960

uccaauauuu gucugacacg gaccgaccgc ggcugguacu gcgauaacgc ugggucuguc     1020

uccuucuuuc cucaggccga gacguguaag gugcagagca auagaguuuu cugcgacaca     1080

augaacucuc uuacccugcc gagcgaagug aaucucugca acgucgauau cuuuaauccc     1140

aaauaugacu guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc     1200

cugggagcga uugugucuug cuacggcaag acaaaaugua cggccuccaa caagaaucgg     1260

gggaucauca agaccuucag caacggaugc gacuauguuu cuaauaaagg cguggacaca     1320

gucuccgugg gcaacacccu uuacuguguu aauaagcaag aggggcagag ccuguaugug     1380

aaaggagagc cuauuaucaa cuuuuacgau ccccucgucu ucccuuccga cgaauuugau     1440

gcuucuauua gccaggugaa cgagaagauc aaucaguccc uggccuucau ucgcaaaucu     1500

gacgaacugc uccacaacgu gaaugcuggc aagagcacaa ccaacaucau gauuacgacc     1560

aucaucauug uuaucauugu cauccugcuu ucccugauug ccguggggcu ccugcuguau     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3712
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3712
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccugaa agcaaacgca      120

auuacuacaa uacuaacagc aguaaccuuu ugcuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacuug cucagcaguc ucaaaaggcu aucuaggagc acuacgaaca      240

gguugguaua cuucagucau aacaauagaa uuaucaaaca uaaaagaaau uaaauguaac      300

ggaacugacg caaaaguaaa acucaucaaa caagaacucg auaaauacaa aaacgcugua      360

accgacuuac aacuacuaau gcaaucaacu ccagcaacag gcuccggauc cgcaauaugc      420

agugguguag caguaugcaa aguccuacac cuagaaggag aaguaaauaa gauaaaaucu      480

gcucuacuau caacaaauaa agcaguuguc ucccuaucaa auggagucuc aguacucacc      540

uucaaaguau uagaccucaa aaacuacaua gacaaacaac uauuaccaau acucaacaaa      600

caauccugcu ccaucccuaa cauagaaacc guaaucgaau uucaacaaaa aaauaacaga      660

cucuuagaaa uaacuagaga auuuucaguu aaugcaggcg ugacaacacc aguaucaaca      720

uauaugcuaa caaacuccga acuccuaucc cuaauaaacg acaugccaau cacaaacgac      780

caaaaaaaac uaauguccaa caacguacaa aucguaagac aacaaucaua cucuauaaug      840

ugcauaauaa aagaagaagu acuggccuac guaguacaau uaccacucua cggaguaaua      900

gacaccccau gcuggaaacu ccauacauca ccccuaugca caacaaacac aaaagaagga      960

uccaacauau gucucacuag aacagacaga ggcugguacu gcgacaacgc uggauccguc     1020

ucauucuucc cccaagcaga aacauguaaa guacaaucua auagaguauu uugugacaca     1080

augaacagcc ucacacuacc auccgaaguc aaccuaugua acguagauau auuuaauccc     1140

aaauacgacu gcaaaauaau gacauccaaa acagauguau caucauccgu uaucaccuca     1200

cuaggagcca uaguuucaug cuacggaaaa acaaaaugca cugcaucuaa caaaaauaga     1260

gguauaauaa aaacauuuuc caacggcugc gacuacgucu caaacaaagg cguagacacc     1320

guaucaguag gaaauacauu auauugcgua aauaaacaag aaggccaauc ccuauacgua     1380

aaaggagaac ccaucauaaa cuucuaugac ccacuuguuu uccccucaga cgaauuugac     1440

gccucaauau cacaaguaaa ugaaaaaaua aaccaaucuc uugccuucau uagaaaauca     1500

gacgaauuac uacacaacgu caacgcagga aaaucaacaa caaacaucau gauaacaacg     1560

auaauaauag ucauaauagu aauacuacua ucauuaaucg cagucggacu ccuauuauau     1620

ugcaaagcua gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3713
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3713
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuaaa agccaacgcc      120

auaaccacca uccucaccgc aguaacuuuc ugcuucgcuu ccggccaaaa caucaccgaa      180

gaauuuuacc aaaguaccug cagcgcaguc ucaaaaggau accuaggcgc ccuacgcaca      240

ggcugguaca ccuccgucau uaccaucgaa cucuccaaca ucaaagaaau uaaaugcaac      300

gguacagacg caaaagucaa acucaucaaa caagaacucg acaaauacaa aaacgcaguc      360

accgaccucc aacuccucau gcaauccacc cccgccacag gcucuggcuc cgccaucugc      420

ucaggcguag cagucugcaa aguccugcac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccucu ccaccaacaa ggccgucgua ucccucucaa acggaguuag cguccucacc      540

uucaaagucc uagaccucaa aaacuacauc gauaaacaac uacuccccau ccuaaacaaa      600

caaucaugcu ccaucccaaa caucgaaacc guaaucgagu uccaacaaaa gaacaaccgc      660

cuccucgaaa ucacacguga guucuccguu aacgccggcg ucaccacccc cgucucuaca      720

uacaugcuca ccaacuccga acuccuuucc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguacaa aucguccgac aacaaagcua cuccaucaug      840

ugcaucauca aagaagaagu ccuugcauac gucguucaac uaccccucua cggcguaauc      900

gacacucccu gcuggaaacu ccacaccucc ccgcucugca caaccaacac caaagaaggc      960

agcaacaucu gccucacccg aaccgaccgc ggcugguacu gcgauaacgc cggauccguc     1020

uccuucuucc cacaagcaga aacuugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacuccc ucacacuccc cuccgaaguc aaccugugca acgucgacau cuucaaccca     1140

aaauacgacu gcaaaaucau gaccucaaaa accgacgucu caucuucugu caucaccucu     1200

cucggcgcua ucgucuccug cuauggcaaa accaaaugca ccgccuccaa caagaaccgc     1260

ggcauuauca agaccuucuc caacggcugc gacuacgucu ccaauaaggg cgucgacacc     1320

gucucugucg gcaacacccu uuacugcgua aacaaacaag aaggucaauc ucucuacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccuggucu uccccuccga cgaguucgau     1440

gcaucaaucu cccaagucaa cgaaaagauc aaccaaucuc ucgcuuucau ccgcaaaucc     1500

gacgaacucc uacacaacgu aaacgccggc aaauccacca caaacaucau gaucaccacc     1560

auuaucauag ucaucaucgu cauccuccuc uccuuaaucg ccguuggccu ccuucucuac     1620

ugcaaagccc gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  3714
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3714
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3715
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3715
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3716
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3716
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3717
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3717
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3718
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3718
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3719
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3719
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3720
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3720
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccugaaagc aaacgcaauu acuacaauac      120

uaacagcagu aaccuuuugc uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacuugcuc agcagucuca aaaggcuauc uaggagcacu acgaacaggu ugguauacuu      240

cagucauaac aauagaauua ucaaacauaa aagaaauuaa auguaacgga acugacgcaa      300

aaguaaaacu caucaaacaa gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac      360

uacuaaugca aucaacucca gcaacaggcu ccggauccgc aauaugcagu gguguagcag      420

uaugcaaagu ccuacaccua gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa      480

caaauaaagc aguugucucc cuaucaaaug gagucucagu acucaccuuc aaaguauuag      540

accucaaaaa cuacauagac aaacaacuau uaccaauacu caacaaacaa uccugcucca      600

ucccuaacau agaaaccgua aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa      660

cuagagaauu uucaguuaau gcaggcguga caacaccagu aucaacauau augcuaacaa      720

acuccgaacu ccuaucccua auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaauc guaagacaac aaucauacuc uauaaugugc auaauaaaag      840

aagaaguacu ggccuacgua guacaauuac cacucuacgg aguaauagac accccaugcu      900

ggaaacucca uacaucaccc cuaugcacaa caaacacaaa agaaggaucc aacauauguc      960

ucacuagaac agacagaggc ugguacugcg acaacgcugg auccgucuca uucuuccccc     1020

aagcagaaac auguaaagua caaucuaaua gaguauuuug ugacacaaug aacagccuca     1080

cacuaccauc cgaagucaac cuauguaacg uagauauauu uaaucccaaa uacgacugca     1140

aaauaaugac auccaaaaca gauguaucau cauccguuau caccucacua ggagccauag     1200

uuucaugcua cggaaaaaca aaaugcacug caucuaacaa aaauagaggu auaauaaaaa     1260

cauuuuccaa cggcugcgac uacgucucaa acaaaggcgu agacaccgua ucaguaggaa     1320

auacauuaua uugcguaaau aaacaagaag gccaaucccu auacguaaaa ggagaaccca     1380

ucauaaacuu cuaugaccca cuuguuuucc ccucagacga auuugacgcc ucaauaucac     1440

aaguaaauga aaaaauaaac caaucucuug ccuucauuag aaaaucagac gaauuacuac     1500

acaacgucaa cgcaggaaaa ucaacaacaa acaucaugau aacaacgaua auaauaguca     1560

uaauaguaau acuacuauca uuaaucgcag ucggacuccu auuauauugc aaagcuagau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3721
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3721
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuaaaagc caacgccaua accaccaucc      120

ucaccgcagu aacuuucugc uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa      180

guaccugcag cgcagucuca aaaggauacc uaggcgcccu acgcacaggc ugguacaccu      240

ccgucauuac caucgaacuc uccaacauca aagaaauuaa augcaacggu acagacgcaa      300

aagucaaacu caucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaccuccaac      360

uccucaugca auccaccccc gccacaggcu cuggcuccgc caucugcuca ggcguagcag      420

ucugcaaagu ccugcaccuc gaaggcgaag ucaacaaaau caagucagcc cuccucucca      480

ccaacaaggc cgucguaucc cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacuac uccccauccu aaacaaacaa ucaugcucca      600

ucccaaacau cgaaaccgua aucgaguucc aacaaaagaa caaccgccuc cucgaaauca      660

cacgugaguu cuccguuaac gccggcguca ccacccccgu cucuacauac augcucacca      720

acuccgaacu ccuuucccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguacaaauc guccgacaac aaagcuacuc caucaugugc aucaucaaag      840

aagaaguccu ugcauacguc guucaacuac cccucuacgg cguaaucgac acucccugcu      900

ggaaacucca caccuccccg cucugcacaa ccaacaccaa agaaggcagc aacaucugcc      960

ucacccgaac cgaccgcggc ugguacugcg auaacgccgg auccgucucc uucuucccac     1020

aagcagaaac uugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cacuccccuc cgaagucaac cugugcaacg ucgacaucuu caacccaaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacgucucau cuucugucau caccucucuc ggcgcuaucg     1200

ucuccugcua uggcaaaacc aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca auaagggcgu cgacaccguc ucugucggca     1320

acacccuuua cugcguaaac aaacaagaag gucaaucucu cuacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cuggucuucc ccuccgacga guucgaugca ucaaucuccc     1440

aagucaacga aaagaucaac caaucucucg cuuucauccg caaauccgac gaacuccuac     1500

acaacguaaa cgccggcaaa uccaccacaa acaucaugau caccaccauu aucauaguca     1560

ucaucgucau ccuccucucc uuaaucgccg uuggccuccu ucucuacugc aaagcccgau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  3722
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3722
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3723
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3723
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucugcucc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcg cugcugucca      480

ccaacaaggc cguggucagc cucuccaacg gcgugagcgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag uccugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcucacca      720

acuccgagcu gcugagccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cgcuguacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggaggggucc aacaucugcc      960

ugacccgcac cgaccggggc ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccuga     1080

cccucccguc cgaggucaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccucua cugcgucaac aagcaggagg gccagagccu guacgugaag ggggagccca     1380

ucaucaacuu cuacgacccc cugguguucc cgagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcgggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg uggggcuccu gcuguacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3724
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3724
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3725
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3725
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucuguuca ggcguggcag      420

ucugcaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcc cugcugagua      480

cgaacaaagc uguggucucc cucucuaaug gggugagcgu auuaacuuuu aagguucugg      540

aucuuaagaa cuacaucgac aaacaauugc ugccuauucu aaauaagcag uccuguucaa      600

ucccaaacau agaaaccgug auugaguucc agcagaaaaa uaacaggcuc cuggaaauca      660

cacgggaguu uagugucaau gccggaguga cuaccccggu gagcacauau augcuuacca      720

acucugagcu guugucccuc auuaaugaua ugcccaucac gaacgaccaa aagaaacuga      780

ugucaaacaa uguccagauc guucgccagc agagcuacag uauuaugugc auaaucaagg      840

aagagguguu agcguaugua gugcaacugc cucucuacgg cgucauugau acuccauguu      900

ggaaacuuca uacaucuccc cugugcacca cuaacacaaa ggaaggcucc aauaucuguu      960

ugacccgaac ggaccguggg ugguacugcg auaacgcagg aagcgugucg uucuuuccuc     1020

aggccgagac cuguaagguu cagucuaaua gaguguucug cgacacaaug aacucccuaa     1080

cucugccauc agaagucaau cucugcaacg uggauauauu uaaucccaaa uaugacugua     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccug ggugcuaucg     1200

ugucaugcua cggcaagacc aaauguacag ccaguaacaa gaauaggggg auuaucaaga     1260

ccuucuccaa cggaugcgac uaugucagca auaaaggcgu ggacacuguc ucugugggua     1320

acacgcuuua cuguguuaau aagcaagagg ggcagucacu guaugugaaa ggagagccua     1380

uuauaaacuu uuacgaucca uugguauucc cgagugacga auuugaugca agcaucuccc     1440

aggucaacga gaagauuaau cagucucucg cuuucauccg gaaaucggac gaacuguuac     1500

acaacgugaa ugccggcaag agcacaacca acaucaugau uacuaccaua aucauuguua     1560

ucauugugau ccugcuaucc cucauagcgg ucggccugcu uuuguauugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3726
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3726
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3727
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3727
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucuguagc ggggucgccg      420

ugugcaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcg cuucugagca      480

ccaacaaagc cgucgugucu cucuccaaug gcguuagcgu gcugacauuu aagguccuug      540

aucugaagaa cuacaucgac aaacaacucc ugccuauucu gaauaagcag ucuuguucca      600

ucccgaacau ugaaaccgug aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca      660

cgcgcgaguu uagcgugaau gcuggcguca caacccccgu uucuacauau augcuuacca      720

acuccgagcu gcucagccug auuaaugaua ugccuaucac caacgaccaa aagaaacuua      780

uguccaacaa ugugcagauu gugagacagc agucuuacag caucaugugc auuaucaagg      840

aagagguccu ggccuaugug guucaacucc cccuguacgg ggugaucgau acaccuuguu      900

ggaaacugca uacgagcccc cucugcacca caaacaccaa ggaaggaucc aauauuuguc      960

ugacacggac cgaccgcggc ugguacugcg auaacgcugg gucugucucc uucuuuccuc     1020

aggccgagac guguaaggug cagagcaaua gaguuuucug cgacacaaug aacucucuua     1080

cccugccgag cgaagugaau cucugcaacg ucgauaucuu uaaucccaaa uaugacugua     1140

agauuaugac cuccaaaaca gaugugucua gcuccgucau caccagccug ggagcgauug     1200

ugucuugcua cggcaagaca aaauguacgg ccuccaacaa gaaucggggg aucaucaaga     1260

ccuucagcaa cggaugcgac uauguuucua auaaaggcgu ggacacaguc uccgugggca     1320

acacccuuua cuguguuaau aagcaagagg ggcagagccu guaugugaaa ggagagccua     1380

uuaucaacuu uuacgauccc cucgucuucc cuuccgacga auuugaugcu ucuauuagcc     1440

aggugaacga gaagaucaau cagucccugg ccuucauucg caaaucugac gaacugcucc     1500

acaacgugaa ugcuggcaag agcacaacca acaucaugau uacgaccauc aucauuguua     1560

ucauugucau ccugcuuucc cugauugccg uggggcuccu gcuguauugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3728
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3728
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccugaaagc aaacgcaauu acuacaauac      120

uaacagcagu aaccuuuugc uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacuugcuc agcagucuca aaaggcuauc uaggagcacu acgaacaggu ugguauacuu      240

cagucauaac aauagaauua ucaaacauaa aagaaauuaa auguaacgga acugacgcaa      300

aaguaaaacu caucaaacaa gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac      360

uacuaaugca aucaacucca gcaacaggcu ccggauccgc aauaugcagu gguguagcag      420

uaugcaaagu ccuacaccua gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa      480

caaauaaagc aguugucucc cuaucaaaug gagucucagu acucaccuuc aaaguauuag      540

accucaaaaa cuacauagac aaacaacuau uaccaauacu caacaaacaa uccugcucca      600

ucccuaacau agaaaccgua aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa      660

cuagagaauu uucaguuaau gcaggcguga caacaccagu aucaacauau augcuaacaa      720

acuccgaacu ccuaucccua auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaauc guaagacaac aaucauacuc uauaaugugc auaauaaaag      840

aagaaguacu ggccuacgua guacaauuac cacucuacgg aguaauagac accccaugcu      900

ggaaacucca uacaucaccc cuaugcacaa caaacacaaa agaaggaucc aacauauguc      960

ucacuagaac agacagaggc ugguacugcg acaacgcugg auccgucuca uucuuccccc     1020

aagcagaaac auguaaagua caaucuaaua gaguauuuug ugacacaaug aacagccuca     1080

cacuaccauc cgaagucaac cuauguaacg uagauauauu uaaucccaaa uacgacugca     1140

aaauaaugac auccaaaaca gauguaucau cauccguuau caccucacua ggagccauag     1200

uuucaugcua cggaaaaaca aaaugcacug caucuaacaa aaauagaggu auaauaaaaa     1260

cauuuuccaa cggcugcgac uacgucucaa acaaaggcgu agacaccgua ucaguaggaa     1320

auacauuaua uugcguaaau aaacaagaag gccaaucccu auacguaaaa ggagaaccca     1380

ucauaaacuu cuaugaccca cuuguuuucc ccucagacga auuugacgcc ucaauaucac     1440

aaguaaauga aaaaauaaac caaucucuug ccuucauuag aaaaucagac gaauuacuac     1500

acaacgucaa cgcaggaaaa ucaacaacaa acaucaugau aacaacgaua auaauaguca     1560

uaauaguaau acuacuauca uuaaucgcag ucggacuccu auuauauugc aaagcuagau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3729
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3729
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuaaaagc caacgccaua accaccaucc      120

ucaccgcagu aacuuucugc uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa      180

guaccugcag cgcagucuca aaaggauacc uaggcgcccu acgcacaggc ugguacaccu      240

ccgucauuac caucgaacuc uccaacauca aagaaauuaa augcaacggu acagacgcaa      300

aagucaaacu caucaaacaa gaacucgaca aauacaaaaa cgcagucacc gaccuccaac      360

uccucaugca auccaccccc gccacaggcu cuggcuccgc caucugcuca ggcguagcag      420

ucugcaaagu ccugcaccuc gaaggcgaag ucaacaaaau caagucagcc cuccucucca      480

ccaacaaggc cgucguaucc cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag      540

accucaaaaa cuacaucgau aaacaacuac uccccauccu aaacaaacaa ucaugcucca      600

ucccaaacau cgaaaccgua aucgaguucc aacaaaagaa caaccgccuc cucgaaauca      660

cacgugaguu cuccguuaac gccggcguca ccacccccgu cucuacauac augcucacca      720

acuccgaacu ccuuucccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguacaaauc guccgacaac aaagcuacuc caucaugugc aucaucaaag      840

aagaaguccu ugcauacguc guucaacuac cccucuacgg cguaaucgac acucccugcu      900

ggaaacucca caccuccccg cucugcacaa ccaacaccaa agaaggcagc aacaucugcc      960

ucacccgaac cgaccgcggc ugguacugcg auaacgccgg auccgucucc uucuucccac     1020

aagcagaaac uugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucccuca     1080

cacuccccuc cgaagucaac cugugcaacg ucgacaucuu caacccaaaa uacgacugca     1140

aaaucaugac cucaaaaacc gacgucucau cuucugucau caccucucuc ggcgcuaucg     1200

ucuccugcua uggcaaaacc aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca auaagggcgu cgacaccguc ucugucggca     1320

acacccuuua cugcguaaac aaacaagaag gucaaucucu cuacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cuggucuucc ccuccgacga guucgaugca ucaaucuccc     1440

aagucaacga aaagaucaac caaucucucg cuuucauccg caaauccgac gaacuccuac     1500

acaacguaaa cgccggcaaa uccaccacaa acaucaugau caccaccauu aucauaguca     1560

ucaucgucau ccuccucucc uuaaucgccg uuggccuccu ucucuacugc aaagcccgau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  3730
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3730
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3731
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3731
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3732
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3732
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3733
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3733
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3734
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3734
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3735
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3735
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3736
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3736
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccugaaa gcaaacgcaa uuacuacaau acuaacagca      120

guaaccuuuu gcuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacuugc      180

ucagcagucu caaaaggcua ucuaggagca cuacgaacag guugguauac uucagucaua      240

acaauagaau uaucaaacau aaaagaaauu aaauguaacg gaacugacgc aaaaguaaaa      300

cucaucaaac aagaacucga uaaauacaaa aacgcuguaa ccgacuuaca acuacuaaug      360

caaucaacuc cagcaacagg cuccggaucc gcaauaugca gugguguagc aguaugcaaa      420

guccuacacc uagaaggaga aguaaauaag auaaaaucug cucuacuauc aacaaauaaa      480

gcaguugucu cccuaucaaa uggagucuca guacucaccu ucaaaguauu agaccucaaa      540

aacuacauag acaaacaacu auuaccaaua cucaacaaac aauccugcuc caucccuaac      600

auagaaaccg uaaucgaauu ucaacaaaaa aauaacagac ucuuagaaau aacuagagaa      660

uuuucaguua augcaggcgu gacaacacca guaucaacau auaugcuaac aaacuccgaa      720

cuccuauccc uaauaaacga caugccaauc acaaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa ucguaagaca acaaucauac ucuauaaugu gcauaauaaa agaagaagua      840

cuggccuacg uaguacaauu accacucuac ggaguaauag acaccccaug cuggaaacuc      900

cauacaucac cccuaugcac aacaaacaca aaagaaggau ccaacauaug ucucacuaga      960

acagacagag gcugguacug cgacaacgcu ggauccgucu cauucuuccc ccaagcagaa     1020

acauguaaag uacaaucuaa uagaguauuu ugugacacaa ugaacagccu cacacuacca     1080

uccgaaguca accuauguaa cguagauaua uuuaauccca aauacgacug caaaauaaug     1140

acauccaaaa cagauguauc aucauccguu aucaccucac uaggagccau aguuucaugc     1200

uacggaaaaa caaaaugcac ugcaucuaac aaaaauagag guauaauaaa aacauuuucc     1260

aacggcugcg acuacgucuc aaacaaaggc guagacaccg uaucaguagg aaauacauua     1320

uauugcguaa auaaacaaga aggccaaucc cuauacguaa aaggagaacc caucauaaac     1380

uucuaugacc cacuuguuuu ccccucagac gaauuugacg ccucaauauc acaaguaaau     1440

gaaaaaauaa accaaucucu ugccuucauu agaaaaucag acgaauuacu acacaacguc     1500

aacgcaggaa aaucaacaac aaacaucaug auaacaacga uaauaauagu cauaauagua     1560

auacuacuau cauuaaucgc agucggacuc cuauuauauu gcaaagcuag auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3737
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3737
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuaaaa gccaacgcca uaaccaccau ccucaccgca      120

guaacuuucu gcuucgcuuc cggccaaaac aucaccgaag aauuuuacca aaguaccugc      180

agcgcagucu caaaaggaua ccuaggcgcc cuacgcacag gcugguacac cuccgucauu      240

accaucgaac ucuccaacau caaagaaauu aaaugcaacg guacagacgc aaaagucaaa      300

cucaucaaac aagaacucga caaauacaaa aacgcaguca ccgaccucca acuccucaug      360

caauccaccc ccgccacagg cucuggcucc gccaucugcu caggcguagc agucugcaaa      420

guccugcacc ucgaaggcga agucaacaaa aucaagucag cccuccucuc caccaacaag      480

gccgucguau cccucucaaa cggaguuagc guccucaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu acuccccauc cuaaacaaac aaucaugcuc caucccaaac      600

aucgaaaccg uaaucgaguu ccaacaaaag aacaaccgcc uccucgaaau cacacgugag      660

uucuccguua acgccggcgu caccaccccc gucucuacau acaugcucac caacuccgaa      720

cuccuuuccc ucaucaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguacaaa ucguccgaca acaaagcuac uccaucaugu gcaucaucaa agaagaaguc      840

cuugcauacg ucguucaacu accccucuac ggcguaaucg acacucccug cuggaaacuc      900

cacaccuccc cgcucugcac aaccaacacc aaagaaggca gcaacaucug ccucacccga      960

accgaccgcg gcugguacug cgauaacgcc ggauccgucu ccuucuuccc acaagcagaa     1020

acuugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacacucccc     1080

uccgaaguca accugugcaa cgucgacauc uucaacccaa aauacgacug caaaaucaug     1140

accucaaaaa ccgacgucuc aucuucuguc aucaccucuc ucggcgcuau cgucuccugc     1200

uauggcaaaa ccaaaugcac cgccuccaac aagaaccgcg gcauuaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caauaagggc gucgacaccg ucucugucgg caacacccuu     1320

uacugcguaa acaaacaaga aggucaaucu cucuacguca aaggagaacc caucaucaac     1380

uucuacgacc cccuggucuu ccccuccgac gaguucgaug caucaaucuc ccaagucaac     1440

gaaaagauca accaaucucu cgcuuucauc cgcaaauccg acgaacuccu acacaacgua     1500

aacgccggca aauccaccac aaacaucaug aucaccacca uuaucauagu caucaucguc     1560

auccuccucu ccuuaaucgc cguuggccuc cuucucuacu gcaaagcccg auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  3738
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3738
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3739
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3739
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucugcu ccggcguggc cgugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cgcugcuguc caccaacaag      480

gccgugguca gccucuccaa cggcgugagc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc aguccugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcucac caacuccgag      720

cugcugagcc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccgcuguac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggaggggu ccaacaucug ccugacccgc      960

accgaccggg gcugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccu gacccucccg     1080

uccgagguca accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccuc     1320

uacugcguca acaagcagga gggccagagc cuguacguga agggggagcc caucaucaac     1380

uucuacgacc cccugguguu cccgagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cguggggcuc cugcuguacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3740
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3740
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3741
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3741
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucuguu caggcguggc agucugcaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cccugcugag uacgaacaaa      480

gcuguggucu cccucucuaa uggggugagc guauuaacuu uuaagguucu ggaucuuaag      540

aacuacaucg acaaacaauu gcugccuauu cuaaauaagc aguccuguuc aaucccaaac      600

auagaaaccg ugauugaguu ccagcagaaa aauaacaggc uccuggaaau cacacgggag      660

uuuaguguca augccggagu gacuaccccg gugagcacau auaugcuuac caacucugag      720

cuguuguccc ucauuaauga uaugcccauc acgaacgacc aaaagaaacu gaugucaaac      780

aauguccaga ucguucgcca gcagagcuac aguauuaugu gcauaaucaa ggaagaggug      840

uuagcguaug uagugcaacu gccucucuac ggcgucauug auacuccaug uuggaaacuu      900

cauacaucuc cccugugcac cacuaacaca aaggaaggcu ccaauaucug uuugacccga      960

acggaccgug ggugguacug cgauaacgca ggaagcgugu cguucuuucc ucaggccgag     1020

accuguaagg uucagucuaa uagaguguuc ugcgacacaa ugaacucccu aacucugcca     1080

ucagaaguca aucucugcaa cguggauaua uuuaauccca aauaugacug uaagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ugggugcuau cgugucaugc     1200

uacggcaaga ccaaauguac agccaguaac aagaauaggg ggauuaucaa gaccuucucc     1260

aacggaugcg acuaugucag caauaaaggc guggacacug ucucuguggg uaacacgcuu     1320

uacuguguua auaagcaaga ggggcaguca cuguauguga aaggagagcc uauuauaaac     1380

uuuuacgauc cauugguauu cccgagugac gaauuugaug caagcaucuc ccaggucaac     1440

gagaagauua aucagucucu cgcuuucauc cggaaaucgg acgaacuguu acacaacgug     1500

aaugccggca agagcacaac caacaucaug auuacuacca uaaucauugu uaucauugug     1560

auccugcuau cccucauagc ggucggccug cuuuuguauu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3742
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3742
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3743
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3743
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucugua gcggggucgc cgugugcaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cgcuucugag caccaacaaa      480

gccgucgugu cucucuccaa uggcguuagc gugcugacau uuaagguccu ugaucugaag      540

aacuacaucg acaaacaacu ccugccuauu cugaauaagc agucuuguuc caucccgaac      600

auugaaaccg ugaucgaguu ccagcagaaa aauaaccggc uccuggaaau cacgcgcgag      660

uuuagcguga augcuggcgu cacaaccccc guuucuacau auaugcuuac caacuccgag      720

cugcucagcc ugauuaauga uaugccuauc accaacgacc aaaagaaacu uauguccaac      780

aaugugcaga uugugagaca gcagucuuac agcaucaugu gcauuaucaa ggaagagguc      840

cuggccuaug ugguucaacu cccccuguac ggggugaucg auacaccuug uuggaaacug      900

cauacgagcc cccucugcac cacaaacacc aaggaaggau ccaauauuug ucugacacgg      960

accgaccgcg gcugguacug cgauaacgcu gggucugucu ccuucuuucc ucaggccgag     1020

acguguaagg ugcagagcaa uagaguuuuc ugcgacacaa ugaacucucu uacccugccg     1080

agcgaaguga aucucugcaa cgucgauauc uuuaauccca aauaugacug uaagauuaug     1140

accuccaaaa cagauguguc uagcuccguc aucaccagcc ugggagcgau ugugucuugc     1200

uacggcaaga caaaauguac ggccuccaac aagaaucggg ggaucaucaa gaccuucagc     1260

aacggaugcg acuauguuuc uaauaaaggc guggacacag ucuccguggg caacacccuu     1320

uacuguguua auaagcaaga ggggcagagc cuguauguga aaggagagcc uauuaucaac     1380

uuuuacgauc cccucgucuu cccuuccgac gaauuugaug cuucuauuag ccaggugaac     1440

gagaagauca aucagucccu ggccuucauu cgcaaaucug acgaacugcu ccacaacgug     1500

aaugcuggca agagcacaac caacaucaug auuacgacca ucaucauugu uaucauuguc     1560

auccugcuuu cccugauugc cguggggcuc cugcuguauu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3744
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3744
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccugaaa gcaaacgcaa uuacuacaau acuaacagca      120

guaaccuuuu gcuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacuugc      180

ucagcagucu caaaaggcua ucuaggagca cuacgaacag guugguauac uucagucaua      240

acaauagaau uaucaaacau aaaagaaauu aaauguaacg gaacugacgc aaaaguaaaa      300

cucaucaaac aagaacucga uaaauacaaa aacgcuguaa ccgacuuaca acuacuaaug      360

caaucaacuc cagcaacagg cuccggaucc gcaauaugca gugguguagc aguaugcaaa      420

guccuacacc uagaaggaga aguaaauaag auaaaaucug cucuacuauc aacaaauaaa      480

gcaguugucu cccuaucaaa uggagucuca guacucaccu ucaaaguauu agaccucaaa      540

aacuacauag acaaacaacu auuaccaaua cucaacaaac aauccugcuc caucccuaac      600

auagaaaccg uaaucgaauu ucaacaaaaa aauaacagac ucuuagaaau aacuagagaa      660

uuuucaguua augcaggcgu gacaacacca guaucaacau auaugcuaac aaacuccgaa      720

cuccuauccc uaauaaacga caugccaauc acaaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa ucguaagaca acaaucauac ucuauaaugu gcauaauaaa agaagaagua      840

cuggccuacg uaguacaauu accacucuac ggaguaauag acaccccaug cuggaaacuc      900

cauacaucac cccuaugcac aacaaacaca aaagaaggau ccaacauaug ucucacuaga      960

acagacagag gcugguacug cgacaacgcu ggauccgucu cauucuuccc ccaagcagaa     1020

acauguaaag uacaaucuaa uagaguauuu ugugacacaa ugaacagccu cacacuacca     1080

uccgaaguca accuauguaa cguagauaua uuuaauccca aauacgacug caaaauaaug     1140

acauccaaaa cagauguauc aucauccguu aucaccucac uaggagccau aguuucaugc     1200

uacggaaaaa caaaaugcac ugcaucuaac aaaaauagag guauaauaaa aacauuuucc     1260

aacggcugcg acuacgucuc aaacaaaggc guagacaccg uaucaguagg aaauacauua     1320

uauugcguaa auaaacaaga aggccaaucc cuauacguaa aaggagaacc caucauaaac     1380

uucuaugacc cacuuguuuu ccccucagac gaauuugacg ccucaauauc acaaguaaau     1440

gaaaaaauaa accaaucucu ugccuucauu agaaaaucag acgaauuacu acacaacguc     1500

aacgcaggaa aaucaacaac aaacaucaug auaacaacga uaauaauagu cauaauagua     1560

auacuacuau cauuaaucgc agucggacuc cuauuauauu gcaaagcuag auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3745
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3745
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuaaaa gccaacgcca uaaccaccau ccucaccgca      120

guaacuuucu gcuucgcuuc cggccaaaac aucaccgaag aauuuuacca aaguaccugc      180

agcgcagucu caaaaggaua ccuaggcgcc cuacgcacag gcugguacac cuccgucauu      240

accaucgaac ucuccaacau caaagaaauu aaaugcaacg guacagacgc aaaagucaaa      300

cucaucaaac aagaacucga caaauacaaa aacgcaguca ccgaccucca acuccucaug      360

caauccaccc ccgccacagg cucuggcucc gccaucugcu caggcguagc agucugcaaa      420

guccugcacc ucgaaggcga agucaacaaa aucaagucag cccuccucuc caccaacaag      480

gccgucguau cccucucaaa cggaguuagc guccucaccu ucaaaguccu agaccucaaa      540

aacuacaucg auaaacaacu acuccccauc cuaaacaaac aaucaugcuc caucccaaac      600

aucgaaaccg uaaucgaguu ccaacaaaag aacaaccgcc uccucgaaau cacacgugag      660

uucuccguua acgccggcgu caccaccccc gucucuacau acaugcucac caacuccgaa      720

cuccuuuccc ucaucaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguacaaa ucguccgaca acaaagcuac uccaucaugu gcaucaucaa agaagaaguc      840

cuugcauacg ucguucaacu accccucuac ggcguaaucg acacucccug cuggaaacuc      900

cacaccuccc cgcucugcac aaccaacacc aaagaaggca gcaacaucug ccucacccga      960

accgaccgcg gcugguacug cgauaacgcc ggauccgucu ccuucuuccc acaagcagaa     1020

acuugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucccu cacacucccc     1080

uccgaaguca accugugcaa cgucgacauc uucaacccaa aauacgacug caaaaucaug     1140

accucaaaaa ccgacgucuc aucuucuguc aucaccucuc ucggcgcuau cgucuccugc     1200

uauggcaaaa ccaaaugcac cgccuccaac aagaaccgcg gcauuaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caauaagggc gucgacaccg ucucugucgg caacacccuu     1320

uacugcguaa acaaacaaga aggucaaucu cucuacguca aaggagaacc caucaucaac     1380

uucuacgacc cccuggucuu ccccuccgac gaguucgaug caucaaucuc ccaagucaac     1440

gaaaagauca accaaucucu cgcuuucauc cgcaaauccg acgaacuccu acacaacgua     1500

aacgccggca aauccaccac aaacaucaug aucaccacca uuaucauagu caucaucguc     1560

auccuccucu ccuuaaucgc cguuggccuc cuucucuacu gcaaagcccg auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  3746
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3746
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3747
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3747
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3748
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3748
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3749
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3749
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3750
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3750
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3751
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3751
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3752
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3752
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccugaaagca      120

aacgcaauua cuacaauacu aacagcagua accuuuugcu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacuugcuca gcagucucaa aaggcuaucu aggagcacua      240

cgaacagguu gguauacuuc agucauaaca auagaauuau caaacauaaa agaaauuaaa      300

uguaacggaa cugacgcaaa aguaaaacuc aucaaacaag aacucgauaa auacaaaaac      360

gcuguaaccg acuuacaacu acuaaugcaa ucaacuccag caacaggcuc cggauccgca      420

auaugcagug guguagcagu augcaaaguc cuacaccuag aaggagaagu aaauaagaua      480

aaaucugcuc uacuaucaac aaauaaagca guugucuccc uaucaaaugg agucucagua      540

cucaccuuca aaguauuaga ccucaaaaac uacauagaca aacaacuauu accaauacuc      600

aacaaacaau ccugcuccau cccuaacaua gaaaccguaa ucgaauuuca acaaaaaaau      660

aacagacucu uagaaauaac uagagaauuu ucaguuaaug caggcgugac aacaccagua      720

ucaacauaua ugcuaacaaa cuccgaacuc cuaucccuaa uaaacgacau gccaaucaca      780

aacgaccaaa aaaaacuaau guccaacaac guacaaaucg uaagacaaca aucauacucu      840

auaaugugca uaauaaaaga agaaguacug gccuacguag uacaauuacc acucuacgga      900

guaauagaca ccccaugcug gaaacuccau acaucacccc uaugcacaac aaacacaaaa      960

gaaggaucca acauaugucu cacuagaaca gacagaggcu gguacugcga caacgcugga     1020

uccgucucau ucuuccccca agcagaaaca uguaaaguac aaucuaauag aguauuuugu     1080

gacacaauga acagccucac acuaccaucc gaagucaacc uauguaacgu agauauauuu     1140

aaucccaaau acgacugcaa aauaaugaca uccaaaacag auguaucauc auccguuauc     1200

accucacuag gagccauagu uucaugcuac ggaaaaacaa aaugcacugc aucuaacaaa     1260

aauagaggua uaauaaaaac auuuuccaac ggcugcgacu acgucucaaa caaaggcgua     1320

gacaccguau caguaggaaa uacauuauau ugcguaaaua aacaagaagg ccaaucccua     1380

uacguaaaag gagaacccau cauaaacuuc uaugacccac uuguuuuccc cucagacgaa     1440

uuugacgccu caauaucaca aguaaaugaa aaaauaaacc aaucucuugc cuucauuaga     1500

aaaucagacg aauuacuaca caacgucaac gcaggaaaau caacaacaaa caucaugaua     1560

acaacgauaa uaauagucau aauaguaaua cuacuaucau uaaucgcagu cggacuccua     1620

uuauauugca aagcuagaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3753
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3753
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuaaaagcc      120

aacgccauaa ccaccauccu caccgcagua acuuucugcu ucgcuuccgg ccaaaacauc      180

accgaagaau uuuaccaaag uaccugcagc gcagucucaa aaggauaccu aggcgcccua      240

cgcacaggcu gguacaccuc cgucauuacc aucgaacucu ccaacaucaa agaaauuaaa      300

ugcaacggua cagacgcaaa agucaaacuc aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg accuccaacu ccucaugcaa uccacccccg ccacaggcuc uggcuccgcc      420

aucugcucag gcguagcagu cugcaaaguc cugcaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccucuccac caacaaggcc gucguauccc ucucaaacgg aguuagcguc      540

cucaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuacu ccccauccua      600

aacaaacaau caugcuccau cccaaacauc gaaaccguaa ucgaguucca acaaaagaac      660

aaccgccucc ucgaaaucac acgugaguuc uccguuaacg ccggcgucac cacccccguc      720

ucuacauaca ugcucaccaa cuccgaacuc cuuucccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guacaaaucg uccgacaaca aagcuacucc      840

aucaugugca ucaucaaaga agaaguccuu gcauacgucg uucaacuacc ccucuacggc      900

guaaucgaca cucccugcug gaaacuccac accuccccgc ucugcacaac caacaccaaa      960

gaaggcagca acaucugccu cacccgaacc gaccgcggcu gguacugcga uaacgccgga     1020

uccgucuccu ucuucccaca agcagaaacu ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac acuccccucc gaagucaacc ugugcaacgu cgacaucuuc     1140

aacccaaaau acgacugcaa aaucaugacc ucaaaaaccg acgucucauc uucugucauc     1200

accucucucg gcgcuaucgu cuccugcuau ggcaaaacca aaugcaccgc cuccaacaag     1260

aaccgcggca uuaucaagac cuucuccaac ggcugcgacu acgucuccaa uaagggcguc     1320

gacaccgucu cugucggcaa cacccuuuac ugcguaaaca aacaagaagg ucaaucucuc     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc uggucuuccc cuccgacgag     1440

uucgaugcau caaucuccca agucaacgaa aagaucaacc aaucucucgc uuucauccgc     1500

aaauccgacg aacuccuaca caacguaaac gccggcaaau ccaccacaaa caucaugauc     1560

accaccauua ucauagucau caucgucauc cuccucuccu uaaucgccgu uggccuccuu     1620

cucuacugca aagcccgaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  3754
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3754
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3755
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3755
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucugcuccg gcguggccgu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgcgc ugcuguccac caacaaggcc guggucagcc ucuccaacgg cgugagcgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcagu ccugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcucaccaa cuccgagcug cugagccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc gcuguacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gaggggucca acaucugccu gacccgcacc gaccggggcu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccugac ccucccgucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccucuac ugcgucaaca agcaggaggg ccagagccug     1380

uacgugaagg gggagcccau caucaacuuc uacgaccccc ugguguuccc gagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcgggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu ggggcuccug     1620

cuguacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3756
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3756
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3757
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3757
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucuguucag gcguggcagu cugcaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgccc ugcugaguac gaacaaagcu guggucuccc ucucuaaugg ggugagcgua      540

uuaacuuuua agguucugga ucuuaagaac uacaucgaca aacaauugcu gccuauucua      600

aauaagcagu ccuguucaau cccaaacaua gaaaccguga uugaguucca gcagaaaaau      660

aacaggcucc uggaaaucac acgggaguuu agugucaaug ccggagugac uaccccggug      720

agcacauaua ugcuuaccaa cucugagcug uugucccuca uuaaugauau gcccaucacg      780

aacgaccaaa agaaacugau gucaaacaau guccagaucg uucgccagca gagcuacagu      840

auuaugugca uaaucaagga agagguguua gcguauguag ugcaacugcc ucucuacggc      900

gucauugaua cuccauguug gaaacuucau acaucucccc ugugcaccac uaacacaaag      960

gaaggcucca auaucuguuu gacccgaacg gaccgugggu gguacugcga uaacgcagga     1020

agcgugucgu ucuuuccuca ggccgagacc uguaagguuc agucuaauag aguguucugc     1080

gacacaauga acucccuaac ucugccauca gaagucaauc ucugcaacgu ggauauauuu     1140

aaucccaaau augacuguaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccugg gugcuaucgu gucaugcuac ggcaagacca aauguacagc caguaacaag     1260

aauaggggga uuaucaagac cuucuccaac ggaugcgacu augucagcaa uaaaggcgug     1320

gacacugucu cuguggguaa cacgcuuuac uguguuaaua agcaagaggg gcagucacug     1380

uaugugaaag gagagccuau uauaaacuuu uacgauccau ugguauuccc gagugacgaa     1440

uuugaugcaa gcaucuccca ggucaacgag aagauuaauc agucucucgc uuucauccgg     1500

aaaucggacg aacuguuaca caacgugaau gccggcaaga gcacaaccaa caucaugauu     1560

acuaccauaa ucauuguuau cauugugauc cugcuauccc ucauagcggu cggccugcuu     1620

uuguauugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3758
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3758
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3759
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3759
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucuguagcg gggucgccgu gugcaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgcgc uucugagcac caacaaagcc gucgugucuc ucuccaaugg cguuagcgug      540

cugacauuua agguccuuga ucugaagaac uacaucgaca aacaacuccu gccuauucug      600

aauaagcagu cuuguuccau cccgaacauu gaaaccguga ucgaguucca gcagaaaaau      660

aaccggcucc uggaaaucac gcgcgaguuu agcgugaaug cuggcgucac aacccccguu      720

ucuacauaua ugcuuaccaa cuccgagcug cucagccuga uuaaugauau gccuaucacc      780

aacgaccaaa agaaacuuau guccaacaau gugcagauug ugagacagca gucuuacagc      840

aucaugugca uuaucaagga agagguccug gccuaugugg uucaacuccc ccuguacggg      900

gugaucgaua caccuuguug gaaacugcau acgagccccc ucugcaccac aaacaccaag      960

gaaggaucca auauuugucu gacacggacc gaccgcggcu gguacugcga uaacgcuggg     1020

ucugucuccu ucuuuccuca ggccgagacg uguaaggugc agagcaauag aguuuucugc     1080

gacacaauga acucucuuac ccugccgagc gaagugaauc ucugcaacgu cgauaucuuu     1140

aaucccaaau augacuguaa gauuaugacc uccaaaacag augugucuag cuccgucauc     1200

accagccugg gagcgauugu gucuugcuac ggcaagacaa aauguacggc cuccaacaag     1260

aaucggggga ucaucaagac cuucagcaac ggaugcgacu auguuucuaa uaaaggcgug     1320

gacacagucu ccgugggcaa cacccuuuac uguguuaaua agcaagaggg gcagagccug     1380

uaugugaaag gagagccuau uaucaacuuu uacgaucccc ucgucuuccc uuccgacgaa     1440

uuugaugcuu cuauuagcca ggugaacgag aagaucaauc agucccuggc cuucauucgc     1500

aaaucugacg aacugcucca caacgugaau gcuggcaaga gcacaaccaa caucaugauu     1560

acgaccauca ucauuguuau cauugucauc cugcuuuccc ugauugccgu ggggcuccug     1620

cuguauugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3760
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3760
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccugaaagca      120

aacgcaauua cuacaauacu aacagcagua accuuuugcu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacuugcuca gcagucucaa aaggcuaucu aggagcacua      240

cgaacagguu gguauacuuc agucauaaca auagaauuau caaacauaaa agaaauuaaa      300

uguaacggaa cugacgcaaa aguaaaacuc aucaaacaag aacucgauaa auacaaaaac      360

gcuguaaccg acuuacaacu acuaaugcaa ucaacuccag caacaggcuc cggauccgca      420

auaugcagug guguagcagu augcaaaguc cuacaccuag aaggagaagu aaauaagaua      480

aaaucugcuc uacuaucaac aaauaaagca guugucuccc uaucaaaugg agucucagua      540

cucaccuuca aaguauuaga ccucaaaaac uacauagaca aacaacuauu accaauacuc      600

aacaaacaau ccugcuccau cccuaacaua gaaaccguaa ucgaauuuca acaaaaaaau      660

aacagacucu uagaaauaac uagagaauuu ucaguuaaug caggcgugac aacaccagua      720

ucaacauaua ugcuaacaaa cuccgaacuc cuaucccuaa uaaacgacau gccaaucaca      780

aacgaccaaa aaaaacuaau guccaacaac guacaaaucg uaagacaaca aucauacucu      840

auaaugugca uaauaaaaga agaaguacug gccuacguag uacaauuacc acucuacgga      900

guaauagaca ccccaugcug gaaacuccau acaucacccc uaugcacaac aaacacaaaa      960

gaaggaucca acauaugucu cacuagaaca gacagaggcu gguacugcga caacgcugga     1020

uccgucucau ucuuccccca agcagaaaca uguaaaguac aaucuaauag aguauuuugu     1080

gacacaauga acagccucac acuaccaucc gaagucaacc uauguaacgu agauauauuu     1140

aaucccaaau acgacugcaa aauaaugaca uccaaaacag auguaucauc auccguuauc     1200

accucacuag gagccauagu uucaugcuac ggaaaaacaa aaugcacugc aucuaacaaa     1260

aauagaggua uaauaaaaac auuuuccaac ggcugcgacu acgucucaaa caaaggcgua     1320

gacaccguau caguaggaaa uacauuauau ugcguaaaua aacaagaagg ccaaucccua     1380

uacguaaaag gagaacccau cauaaacuuc uaugacccac uuguuuuccc cucagacgaa     1440

uuugacgccu caauaucaca aguaaaugaa aaaauaaacc aaucucuugc cuucauuaga     1500

aaaucagacg aauuacuaca caacgucaac gcaggaaaau caacaacaaa caucaugaua     1560

acaacgauaa uaauagucau aauaguaaua cuacuaucau uaaucgcagu cggacuccua     1620

uuauauugca aagcuagaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3761
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3761
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuaaaagcc      120

aacgccauaa ccaccauccu caccgcagua acuuucugcu ucgcuuccgg ccaaaacauc      180

accgaagaau uuuaccaaag uaccugcagc gcagucucaa aaggauaccu aggcgcccua      240

cgcacaggcu gguacaccuc cgucauuacc aucgaacucu ccaacaucaa agaaauuaaa      300

ugcaacggua cagacgcaaa agucaaacuc aucaaacaag aacucgacaa auacaaaaac      360

gcagucaccg accuccaacu ccucaugcaa uccacccccg ccacaggcuc uggcuccgcc      420

aucugcucag gcguagcagu cugcaaaguc cugcaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccucuccac caacaaggcc gucguauccc ucucaaacgg aguuagcguc      540

cucaccuuca aaguccuaga ccucaaaaac uacaucgaua aacaacuacu ccccauccua      600

aacaaacaau caugcuccau cccaaacauc gaaaccguaa ucgaguucca acaaaagaac      660

aaccgccucc ucgaaaucac acgugaguuc uccguuaacg ccggcgucac cacccccguc      720

ucuacauaca ugcucaccaa cuccgaacuc cuuucccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guacaaaucg uccgacaaca aagcuacucc      840

aucaugugca ucaucaaaga agaaguccuu gcauacgucg uucaacuacc ccucuacggc      900

guaaucgaca cucccugcug gaaacuccac accuccccgc ucugcacaac caacaccaaa      960

gaaggcagca acaucugccu cacccgaacc gaccgcggcu gguacugcga uaacgccgga     1020

uccgucuccu ucuucccaca agcagaaacu ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucccucac acuccccucc gaagucaacc ugugcaacgu cgacaucuuc     1140

aacccaaaau acgacugcaa aaucaugacc ucaaaaaccg acgucucauc uucugucauc     1200

accucucucg gcgcuaucgu cuccugcuau ggcaaaacca aaugcaccgc cuccaacaag     1260

aaccgcggca uuaucaagac cuucuccaac ggcugcgacu acgucuccaa uaagggcguc     1320

gacaccgucu cugucggcaa cacccuuuac ugcguaaaca aacaagaagg ucaaucucuc     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc uggucuuccc cuccgacgag     1440

uucgaugcau caaucuccca agucaacgaa aagaucaacc aaucucucgc uuucauccgc     1500

aaauccgacg aacuccuaca caacguaaac gccggcaaau ccaccacaaa caucaugauc     1560

accaccauua ucauagucau caucgucauc cuccucuccu uaaucgccgu uggccuccuu     1620

cucuacugca aagcccgaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  3762
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3762
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3763
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3763
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug      540

gucagccucu ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      780

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac     1020

cggggcuggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1140

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc     1380

gucaacaagc aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac     1440

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3764
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3764
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3765
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3765
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug      540

gucucccucu cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac      600

aucgacaaac aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa      660

accgugauug aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu      720

gucaaugccg gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug      780

ucccucauua augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc      840

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg      900

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      960

ucuccccugu gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac     1020

cguggguggu acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu     1080

aagguucagu cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1140

gucaaucucu gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc     1260

aagaccaaau guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga     1320

ugcgacuaug ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu     1380

guuaauaagc aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac     1440

gauccauugg uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag     1500

auuaaucagu cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc     1560

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1620

cuaucccuca uagcggucgg ccugcuuuug uauugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3766
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3766
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3767
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3767
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc      540

gugucucucu ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac      600

aucgacaaac aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa      660

accgugaucg aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc      720

gugaaugcug gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc      780

agccugauua augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug      840

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc      900

uaugugguuc aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg      960

agcccccucu gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac     1020

cgcggcuggu acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu     1080

aaggugcaga gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1140

gugaaucucu gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc     1200

aaaacagaug ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc     1260

aagacaaaau guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga     1320

ugcgacuaug uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu     1380

guuaauaagc aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac     1440

gauccccucg ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag     1500

aucaaucagu cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu     1560

ggcaagagca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1620

cuuucccuga uugccguggg gcuccugcug uauugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3768
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3768
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu gaaagcaaac gcaauuacua caauacuaac agcaguaacc      180

uuuugcuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac uugcucagca      240

gucucaaaag gcuaucuagg agcacuacga acagguuggu auacuucagu cauaacaaua      300

gaauuaucaa acauaaaaga aauuaaaugu aacggaacug acgcaaaagu aaaacucauc      360

aaacaagaac ucgauaaaua caaaaacgcu guaaccgacu uacaacuacu aaugcaauca      420

acuccagcaa caggcuccgg auccgcaaua ugcaguggug uagcaguaug caaaguccua      480

caccuagaag gagaaguaaa uaagauaaaa ucugcucuac uaucaacaaa uaaagcaguu      540

gucucccuau caaauggagu cucaguacuc accuucaaag uauuagaccu caaaaacuac      600

auagacaaac aacuauuacc aauacucaac aaacaauccu gcuccauccc uaacauagaa      660

accguaaucg aauuucaaca aaaaaauaac agacucuuag aaauaacuag agaauuuuca      720

guuaaugcag gcgugacaac accaguauca acauauaugc uaacaaacuc cgaacuccua      780

ucccuaauaa acgacaugcc aaucacaaac gaccaaaaaa aacuaauguc caacaacgua      840

caaaucguaa gacaacaauc auacucuaua augugcauaa uaaaagaaga aguacuggcc      900

uacguaguac aauuaccacu cuacggagua auagacaccc caugcuggaa acuccauaca      960

ucaccccuau gcacaacaaa cacaaaagaa ggauccaaca uaugucucac uagaacagac     1020

agaggcuggu acugcgacaa cgcuggaucc gucucauucu ucccccaagc agaaacaugu     1080

aaaguacaau cuaauagagu auuuugugac acaaugaaca gccucacacu accauccgaa     1140

gucaaccuau guaacguaga uauauuuaau cccaaauacg acugcaaaau aaugacaucc     1200

aaaacagaug uaucaucauc cguuaucacc ucacuaggag ccauaguuuc augcuacgga     1260

aaaacaaaau gcacugcauc uaacaaaaau agagguauaa uaaaaacauu uuccaacggc     1320

ugcgacuacg ucucaaacaa aggcguagac accguaucag uaggaaauac auuauauugc     1380

guaaauaaac aagaaggcca aucccuauac guaaaaggag aacccaucau aaacuucuau     1440

gacccacuug uuuuccccuc agacgaauuu gacgccucaa uaucacaagu aaaugaaaaa     1500

auaaaccaau cucuugccuu cauuagaaaa ucagacgaau uacuacacaa cgucaacgca     1560

ggaaaaucaa caacaaacau caugauaaca acgauaauaa uagucauaau aguaauacua     1620

cuaucauuaa ucgcagucgg acuccuauua uauugcaaag cuagauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3769
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3769
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu aaaagccaac gccauaacca ccauccucac cgcaguaacu      180

uucugcuucg cuuccggcca aaacaucacc gaagaauuuu accaaaguac cugcagcgca      240

gucucaaaag gauaccuagg cgcccuacgc acaggcuggu acaccuccgu cauuaccauc      300

gaacucucca acaucaaaga aauuaaaugc aacgguacag acgcaaaagu caaacucauc      360

aaacaagaac ucgacaaaua caaaaacgca gucaccgacc uccaacuccu caugcaaucc      420

acccccgcca caggcucugg cuccgccauc ugcucaggcg uagcagucug caaaguccug      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc ucuccaccaa caaggccguc      540

guaucccucu caaacggagu uagcguccuc accuucaaag uccuagaccu caaaaacuac      600

aucgauaaac aacuacuccc cauccuaaac aaacaaucau gcuccauccc aaacaucgaa      660

accguaaucg aguuccaaca aaagaacaac cgccuccucg aaaucacacg ugaguucucc      720

guuaacgccg gcgucaccac ccccgucucu acauacaugc ucaccaacuc cgaacuccuu      780

ucccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacgua      840

caaaucgucc gacaacaaag cuacuccauc augugcauca ucaaagaaga aguccuugca      900

uacgucguuc aacuaccccu cuacggcgua aucgacacuc ccugcuggaa acuccacacc      960

uccccgcucu gcacaaccaa caccaaagaa ggcagcaaca ucugccucac ccgaaccgac     1020

cgcggcuggu acugcgauaa cgccggaucc gucuccuucu ucccacaagc agaaacuugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cccucacacu ccccuccgaa     1140

gucaaccugu gcaacgucga caucuucaac ccaaaauacg acugcaaaau caugaccuca     1200

aaaaccgacg ucucaucuuc ugucaucacc ucucucggcg cuaucgucuc cugcuauggc     1260

aaaaccaaau gcaccgccuc caacaagaac cgcggcauua ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaauaa gggcgucgac accgucucug ucggcaacac ccuuuacugc     1380

guaaacaaac aagaagguca aucucucuac gucaaaggag aacccaucau caacuucuac     1440

gacccccugg ucuuccccuc cgacgaguuc gaugcaucaa ucucccaagu caacgaaaag     1500

aucaaccaau cucucgcuuu cauccgcaaa uccgacgaac uccuacacaa cguaaacgcc     1560

ggcaaaucca ccacaaacau caugaucacc accauuauca uagucaucau cgucauccuc     1620

cucuccuuaa ucgccguugg ccuccuucuc uacugcaaag cccgauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3770
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3770
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3771
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3771
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3772
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3772
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3773
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3773
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3774
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3774
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3775
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3775
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3776
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3776
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccugaaa      120

gcaaacgcaa uuacuacaau acuaacagca guaaccuuuu gcuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacuugc ucagcagucu caaaaggcua ucuaggagca      240

cuacgaacag guugguauac uucagucaua acaauagaau uaucaaacau aaaagaaauu      300

aaauguaacg gaacugacgc aaaaguaaaa cucaucaaac aagaacucga uaaauacaaa      360

aacgcuguaa ccgacuuaca acuacuaaug caaucaacuc cagcaacagg cuccggaucc      420

gcaauaugca gugguguagc aguaugcaaa guccuacacc uagaaggaga aguaaauaag      480

auaaaaucug cucuacuauc aacaaauaaa gcaguugucu cccuaucaaa uggagucuca      540

guacucaccu ucaaaguauu agaccucaaa aacuacauag acaaacaacu auuaccaaua      600

cucaacaaac aauccugcuc caucccuaac auagaaaccg uaaucgaauu ucaacaaaaa      660

aauaacagac ucuuagaaau aacuagagaa uuuucaguua augcaggcgu gacaacacca      720

guaucaacau auaugcuaac aaacuccgaa cuccuauccc uaauaaacga caugccaauc      780

acaaacgacc aaaaaaaacu aauguccaac aacguacaaa ucguaagaca acaaucauac      840

ucuauaaugu gcauaauaaa agaagaagua cuggccuacg uaguacaauu accacucuac      900

ggaguaauag acaccccaug cuggaaacuc cauacaucac cccuaugcac aacaaacaca      960

aaagaaggau ccaacauaug ucucacuaga acagacagag gcugguacug cgacaacgcu     1020

ggauccgucu cauucuuccc ccaagcagaa acauguaaag uacaaucuaa uagaguauuu     1080

ugugacacaa ugaacagccu cacacuacca uccgaaguca accuauguaa cguagauaua     1140

uuuaauccca aauacgacug caaaauaaug acauccaaaa cagauguauc aucauccguu     1200

aucaccucac uaggagccau aguuucaugc uacggaaaaa caaaaugcac ugcaucuaac     1260

aaaaauagag guauaauaaa aacauuuucc aacggcugcg acuacgucuc aaacaaaggc     1320

guagacaccg uaucaguagg aaauacauua uauugcguaa auaaacaaga aggccaaucc     1380

cuauacguaa aaggagaacc caucauaaac uucuaugacc cacuuguuuu ccccucagac     1440

gaauuugacg ccucaauauc acaaguaaau gaaaaaauaa accaaucucu ugccuucauu     1500

agaaaaucag acgaauuacu acacaacguc aacgcaggaa aaucaacaac aaacaucaug     1560

auaacaacga uaauaauagu cauaauagua auacuacuau cauuaaucgc agucggacuc     1620

cuauuauauu gcaaagcuag auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3777
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3777
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuaaaa      120

gccaacgcca uaaccaccau ccucaccgca guaacuuucu gcuucgcuuc cggccaaaac      180

aucaccgaag aauuuuacca aaguaccugc agcgcagucu caaaaggaua ccuaggcgcc      240

cuacgcacag gcugguacac cuccgucauu accaucgaac ucuccaacau caaagaaauu      300

aaaugcaacg guacagacgc aaaagucaaa cucaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaccucca acuccucaug caauccaccc ccgccacagg cucuggcucc      420

gccaucugcu caggcguagc agucugcaaa guccugcacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccucuc caccaacaag gccgucguau cccucucaaa cggaguuagc      540

guccucaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu acuccccauc      600

cuaaacaaac aaucaugcuc caucccaaac aucgaaaccg uaaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacacgugag uucuccguua acgccggcgu caccaccccc      720

gucucuacau acaugcucac caacuccgaa cuccuuuccc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguacaaa ucguccgaca acaaagcuac      840

uccaucaugu gcaucaucaa agaagaaguc cuugcauacg ucguucaacu accccucuac      900

ggcguaaucg acacucccug cuggaaacuc cacaccuccc cgcucugcac aaccaacacc      960

aaagaaggca gcaacaucug ccucacccga accgaccgcg gcugguacug cgauaacgcc     1020

ggauccgucu ccuucuuccc acaagcagaa acuugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacacucccc uccgaaguca accugugcaa cgucgacauc     1140

uucaacccaa aauacgacug caaaaucaug accucaaaaa ccgacgucuc aucuucuguc     1200

aucaccucuc ucggcgcuau cgucuccugc uauggcaaaa ccaaaugcac cgccuccaac     1260

aagaaccgcg gcauuaucaa gaccuucucc aacggcugcg acuacgucuc caauaagggc     1320

gucgacaccg ucucugucgg caacacccuu uacugcguaa acaaacaaga aggucaaucu     1380

cucuacguca aaggagaacc caucaucaac uucuacgacc cccuggucuu ccccuccgac     1440

gaguucgaug caucaaucuc ccaagucaac gaaaagauca accaaucucu cgcuuucauc     1500

cgcaaauccg acgaacuccu acacaacgua aacgccggca aauccaccac aaacaucaug     1560

aucaccacca uuaucauagu caucaucguc auccuccucu ccuuaaucgc cguuggccuc     1620

cuucucuacu gcaaagcccg auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  3778
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3778
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3779
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3779
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3780
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3780
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3781
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3781
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3782
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3782
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3783
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3783
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3784
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3784
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccugaaa      120

gcaaacgcaa uuacuacaau acuaacagca guaaccuuuu gcuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacuugc ucagcagucu caaaaggcua ucuaggagca      240

cuacgaacag guugguauac uucagucaua acaauagaau uaucaaacau aaaagaaauu      300

aaauguaacg gaacugacgc aaaaguaaaa cucaucaaac aagaacucga uaaauacaaa      360

aacgcuguaa ccgacuuaca acuacuaaug caaucaacuc cagcaacagg cuccggaucc      420

gcaauaugca gugguguagc aguaugcaaa guccuacacc uagaaggaga aguaaauaag      480

auaaaaucug cucuacuauc aacaaauaaa gcaguugucu cccuaucaaa uggagucuca      540

guacucaccu ucaaaguauu agaccucaaa aacuacauag acaaacaacu auuaccaaua      600

cucaacaaac aauccugcuc caucccuaac auagaaaccg uaaucgaauu ucaacaaaaa      660

aauaacagac ucuuagaaau aacuagagaa uuuucaguua augcaggcgu gacaacacca      720

guaucaacau auaugcuaac aaacuccgaa cuccuauccc uaauaaacga caugccaauc      780

acaaacgacc aaaaaaaacu aauguccaac aacguacaaa ucguaagaca acaaucauac      840

ucuauaaugu gcauaauaaa agaagaagua cuggccuacg uaguacaauu accacucuac      900

ggaguaauag acaccccaug cuggaaacuc cauacaucac cccuaugcac aacaaacaca      960

aaagaaggau ccaacauaug ucucacuaga acagacagag gcugguacug cgacaacgcu     1020

ggauccgucu cauucuuccc ccaagcagaa acauguaaag uacaaucuaa uagaguauuu     1080

ugugacacaa ugaacagccu cacacuacca uccgaaguca accuauguaa cguagauaua     1140

uuuaauccca aauacgacug caaaauaaug acauccaaaa cagauguauc aucauccguu     1200

aucaccucac uaggagccau aguuucaugc uacggaaaaa caaaaugcac ugcaucuaac     1260

aaaaauagag guauaauaaa aacauuuucc aacggcugcg acuacgucuc aaacaaaggc     1320

guagacaccg uaucaguagg aaauacauua uauugcguaa auaaacaaga aggccaaucc     1380

cuauacguaa aaggagaacc caucauaaac uucuaugacc cacuuguuuu ccccucagac     1440

gaauuugacg ccucaauauc acaaguaaau gaaaaaauaa accaaucucu ugccuucauu     1500

agaaaaucag acgaauuacu acacaacguc aacgcaggaa aaucaacaac aaacaucaug     1560

auaacaacga uaauaauagu cauaauagua auacuacuau cauuaaucgc agucggacuc     1620

cuauuauauu gcaaagcuag auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3785
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3785
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuaaaa      120

gccaacgcca uaaccaccau ccucaccgca guaacuuucu gcuucgcuuc cggccaaaac      180

aucaccgaag aauuuuacca aaguaccugc agcgcagucu caaaaggaua ccuaggcgcc      240

cuacgcacag gcugguacac cuccgucauu accaucgaac ucuccaacau caaagaaauu      300

aaaugcaacg guacagacgc aaaagucaaa cucaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaccucca acuccucaug caauccaccc ccgccacagg cucuggcucc      420

gccaucugcu caggcguagc agucugcaaa guccugcacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccucuc caccaacaag gccgucguau cccucucaaa cggaguuagc      540

guccucaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu acuccccauc      600

cuaaacaaac aaucaugcuc caucccaaac aucgaaaccg uaaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacacgugag uucuccguua acgccggcgu caccaccccc      720

gucucuacau acaugcucac caacuccgaa cuccuuuccc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguacaaa ucguccgaca acaaagcuac      840

uccaucaugu gcaucaucaa agaagaaguc cuugcauacg ucguucaacu accccucuac      900

ggcguaaucg acacucccug cuggaaacuc cacaccuccc cgcucugcac aaccaacacc      960

aaagaaggca gcaacaucug ccucacccga accgaccgcg gcugguacug cgauaacgcc     1020

ggauccgucu ccuucuuccc acaagcagaa acuugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacacucccc uccgaaguca accugugcaa cgucgacauc     1140

uucaacccaa aauacgacug caaaaucaug accucaaaaa ccgacgucuc aucuucuguc     1200

aucaccucuc ucggcgcuau cgucuccugc uauggcaaaa ccaaaugcac cgccuccaac     1260

aagaaccgcg gcauuaucaa gaccuucucc aacggcugcg acuacgucuc caauaagggc     1320

gucgacaccg ucucugucgg caacacccuu uacugcguaa acaaacaaga aggucaaucu     1380

cucuacguca aaggagaacc caucaucaac uucuacgacc cccuggucuu ccccuccgac     1440

gaguucgaug caucaaucuc ccaagucaac gaaaagauca accaaucucu cgcuuucauc     1500

cgcaaauccg acgaacuccu acacaacgua aacgccggca aauccaccac aaacaucaug     1560

aucaccacca uuaucauagu caucaucguc auccuccucu ccuuaaucgc cguuggccuc     1620

cuucucuacu gcaaagcccg auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  3786
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3786
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3787
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3787
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3788
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3788
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3789
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3789
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3790
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3790
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3791
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3791
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3792
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3792
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccugaaa      120

gcaaacgcaa uuacuacaau acuaacagca guaaccuuuu gcuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacuugc ucagcagucu caaaaggcua ucuaggagca      240

cuacgaacag guugguauac uucagucaua acaauagaau uaucaaacau aaaagaaauu      300

aaauguaacg gaacugacgc aaaaguaaaa cucaucaaac aagaacucga uaaauacaaa      360

aacgcuguaa ccgacuuaca acuacuaaug caaucaacuc cagcaacagg cuccggaucc      420

gcaauaugca gugguguagc aguaugcaaa guccuacacc uagaaggaga aguaaauaag      480

auaaaaucug cucuacuauc aacaaauaaa gcaguugucu cccuaucaaa uggagucuca      540

guacucaccu ucaaaguauu agaccucaaa aacuacauag acaaacaacu auuaccaaua      600

cucaacaaac aauccugcuc caucccuaac auagaaaccg uaaucgaauu ucaacaaaaa      660

aauaacagac ucuuagaaau aacuagagaa uuuucaguua augcaggcgu gacaacacca      720

guaucaacau auaugcuaac aaacuccgaa cuccuauccc uaauaaacga caugccaauc      780

acaaacgacc aaaaaaaacu aauguccaac aacguacaaa ucguaagaca acaaucauac      840

ucuauaaugu gcauaauaaa agaagaagua cuggccuacg uaguacaauu accacucuac      900

ggaguaauag acaccccaug cuggaaacuc cauacaucac cccuaugcac aacaaacaca      960

aaagaaggau ccaacauaug ucucacuaga acagacagag gcugguacug cgacaacgcu     1020

ggauccgucu cauucuuccc ccaagcagaa acauguaaag uacaaucuaa uagaguauuu     1080

ugugacacaa ugaacagccu cacacuacca uccgaaguca accuauguaa cguagauaua     1140

uuuaauccca aauacgacug caaaauaaug acauccaaaa cagauguauc aucauccguu     1200

aucaccucac uaggagccau aguuucaugc uacggaaaaa caaaaugcac ugcaucuaac     1260

aaaaauagag guauaauaaa aacauuuucc aacggcugcg acuacgucuc aaacaaaggc     1320

guagacaccg uaucaguagg aaauacauua uauugcguaa auaaacaaga aggccaaucc     1380

cuauacguaa aaggagaacc caucauaaac uucuaugacc cacuuguuuu ccccucagac     1440

gaauuugacg ccucaauauc acaaguaaau gaaaaaauaa accaaucucu ugccuucauu     1500

agaaaaucag acgaauuacu acacaacguc aacgcaggaa aaucaacaac aaacaucaug     1560

auaacaacga uaauaauagu cauaauagua auacuacuau cauuaaucgc agucggacuc     1620

cuauuauauu gcaaagcuag auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3793
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3793
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuaaaa      120

gccaacgcca uaaccaccau ccucaccgca guaacuuucu gcuucgcuuc cggccaaaac      180

aucaccgaag aauuuuacca aaguaccugc agcgcagucu caaaaggaua ccuaggcgcc      240

cuacgcacag gcugguacac cuccgucauu accaucgaac ucuccaacau caaagaaauu      300

aaaugcaacg guacagacgc aaaagucaaa cucaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaccucca acuccucaug caauccaccc ccgccacagg cucuggcucc      420

gccaucugcu caggcguagc agucugcaaa guccugcacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccucuc caccaacaag gccgucguau cccucucaaa cggaguuagc      540

guccucaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu acuccccauc      600

cuaaacaaac aaucaugcuc caucccaaac aucgaaaccg uaaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacacgugag uucuccguua acgccggcgu caccaccccc      720

gucucuacau acaugcucac caacuccgaa cuccuuuccc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguacaaa ucguccgaca acaaagcuac      840

uccaucaugu gcaucaucaa agaagaaguc cuugcauacg ucguucaacu accccucuac      900

ggcguaaucg acacucccug cuggaaacuc cacaccuccc cgcucugcac aaccaacacc      960

aaagaaggca gcaacaucug ccucacccga accgaccgcg gcugguacug cgauaacgcc     1020

ggauccgucu ccuucuuccc acaagcagaa acuugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacacucccc uccgaaguca accugugcaa cgucgacauc     1140

uucaacccaa aauacgacug caaaaucaug accucaaaaa ccgacgucuc aucuucuguc     1200

aucaccucuc ucggcgcuau cgucuccugc uauggcaaaa ccaaaugcac cgccuccaac     1260

aagaaccgcg gcauuaucaa gaccuucucc aacggcugcg acuacgucuc caauaagggc     1320

gucgacaccg ucucugucgg caacacccuu uacugcguaa acaaacaaga aggucaaucu     1380

cucuacguca aaggagaacc caucaucaac uucuacgacc cccuggucuu ccccuccgac     1440

gaguucgaug caucaaucuc ccaagucaac gaaaagauca accaaucucu cgcuuucauc     1500

cgcaaauccg acgaacuccu acacaacgua aacgccggca aauccaccac aaacaucaug     1560

aucaccacca uuaucauagu caucaucguc auccuccucu ccuuaaucgc cguuggccuc     1620

cuucucuacu gcaaagcccg auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  3794
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3794
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3795
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3795
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucugcu ccggcguggc cgugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cgcugcuguc caccaacaag gccgugguca gccucuccaa cggcgugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccuc uacugcguca acaagcagga gggccagagc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3796
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3796
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3797
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3797
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucuguu caggcguggc agucugcaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cccugcugag uacgaacaaa gcuguggucu cccucucuaa uggggugagc      540

guauuaacuu uuaagguucu ggaucuuaag aacuacaucg acaaacaauu gcugccuauu      600

cuaaauaagc aguccuguuc aaucccaaac auagaaaccg ugauugaguu ccagcagaaa      660

aauaacaggc uccuggaaau cacacgggag uuuaguguca augccggagu gacuaccccg      720

gugagcacau auaugcuuac caacucugag cuguuguccc ucauuaauga uaugcccauc      780

acgaacgacc aaaagaaacu gaugucaaac aauguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcguaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaacaca      960

aaggaaggcu ccaauaucug uuugacccga acggaccgug ggugguacug cgauaacgca     1020

ggaagcgugu cguucuuucc ucaggccgag accuguaagg uucagucuaa uagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa cguggauaua     1140

uuuaauccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggugcuau cgugucaugc uacggcaaga ccaaauguac agccaguaac     1260

aagaauaggg ggauuaucaa gaccuucucc aacggaugcg acuaugucag caauaaaggc     1320

guggacacug ucucuguggg uaacacgcuu uacuguguua auaagcaaga ggggcaguca     1380

cuguauguga aaggagagcc uauuauaaac uuuuacgauc cauugguauu cccgagugac     1440

gaauuugaug caagcaucuc ccaggucaac gagaagauua aucagucucu cgcuuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugccggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc ggucggccug     1620

cuuuuguauu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3798
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3798
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3799
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3799
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucugua gcggggucgc cgugugcaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cgcuucugag caccaacaaa gccgucgugu cucucuccaa uggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aacuacaucg acaaacaacu ccugccuauu      600

cugaauaagc agucuuguuc caucccgaac auugaaaccg ugaucgaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuagcguga augcuggcgu cacaaccccc      720

guuucuacau auaugcuuac caacuccgag cugcucagcc ugauuaauga uaugccuauc      780

accaacgacc aaaagaaacu uauguccaac aaugugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggccuaug ugguucaacu cccccuguac      900

ggggugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaacacc      960

aaggaaggau ccaauauuug ucugacacgg accgaccgcg gcugguacug cgauaacgcu     1020

gggucugucu ccuucuuucc ucaggccgag acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa cgucgauauc     1140

uuuaauccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggagcgau ugugucuugc uacggcaaga caaaauguac ggccuccaac     1260

aagaaucggg ggaucaucaa gaccuucagc aacggaugcg acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg caacacccuu uacuguguua auaagcaaga ggggcagagc     1380

cuguauguga aaggagagcc uauuaucaac uuuuacgauc cccucgucuu cccuuccgac     1440

gaauuugaug cuucuauuag ccaggugaac gagaagauca aucagucccu ggccuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugcuggca agagcacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cguggggcuc     1620

cugcuguauu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3800
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3800
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccugaaa      120

gcaaacgcaa uuacuacaau acuaacagca guaaccuuuu gcuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacuugc ucagcagucu caaaaggcua ucuaggagca      240

cuacgaacag guugguauac uucagucaua acaauagaau uaucaaacau aaaagaaauu      300

aaauguaacg gaacugacgc aaaaguaaaa cucaucaaac aagaacucga uaaauacaaa      360

aacgcuguaa ccgacuuaca acuacuaaug caaucaacuc cagcaacagg cuccggaucc      420

gcaauaugca gugguguagc aguaugcaaa guccuacacc uagaaggaga aguaaauaag      480

auaaaaucug cucuacuauc aacaaauaaa gcaguugucu cccuaucaaa uggagucuca      540

guacucaccu ucaaaguauu agaccucaaa aacuacauag acaaacaacu auuaccaaua      600

cucaacaaac aauccugcuc caucccuaac auagaaaccg uaaucgaauu ucaacaaaaa      660

aauaacagac ucuuagaaau aacuagagaa uuuucaguua augcaggcgu gacaacacca      720

guaucaacau auaugcuaac aaacuccgaa cuccuauccc uaauaaacga caugccaauc      780

acaaacgacc aaaaaaaacu aauguccaac aacguacaaa ucguaagaca acaaucauac      840

ucuauaaugu gcauaauaaa agaagaagua cuggccuacg uaguacaauu accacucuac      900

ggaguaauag acaccccaug cuggaaacuc cauacaucac cccuaugcac aacaaacaca      960

aaagaaggau ccaacauaug ucucacuaga acagacagag gcugguacug cgacaacgcu     1020

ggauccgucu cauucuuccc ccaagcagaa acauguaaag uacaaucuaa uagaguauuu     1080

ugugacacaa ugaacagccu cacacuacca uccgaaguca accuauguaa cguagauaua     1140

uuuaauccca aauacgacug caaaauaaug acauccaaaa cagauguauc aucauccguu     1200

aucaccucac uaggagccau aguuucaugc uacggaaaaa caaaaugcac ugcaucuaac     1260

aaaaauagag guauaauaaa aacauuuucc aacggcugcg acuacgucuc aaacaaaggc     1320

guagacaccg uaucaguagg aaauacauua uauugcguaa auaaacaaga aggccaaucc     1380

cuauacguaa aaggagaacc caucauaaac uucuaugacc cacuuguuuu ccccucagac     1440

gaauuugacg ccucaauauc acaaguaaau gaaaaaauaa accaaucucu ugccuucauu     1500

agaaaaucag acgaauuacu acacaacguc aacgcaggaa aaucaacaac aaacaucaug     1560

auaacaacga uaauaauagu cauaauagua auacuacuau cauuaaucgc agucggacuc     1620

cuauuauauu gcaaagcuag auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3801
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3801
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuaaaa      120

gccaacgcca uaaccaccau ccucaccgca guaacuuucu gcuucgcuuc cggccaaaac      180

aucaccgaag aauuuuacca aaguaccugc agcgcagucu caaaaggaua ccuaggcgcc      240

cuacgcacag gcugguacac cuccgucauu accaucgaac ucuccaacau caaagaaauu      300

aaaugcaacg guacagacgc aaaagucaaa cucaucaaac aagaacucga caaauacaaa      360

aacgcaguca ccgaccucca acuccucaug caauccaccc ccgccacagg cucuggcucc      420

gccaucugcu caggcguagc agucugcaaa guccugcacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccucuc caccaacaag gccgucguau cccucucaaa cggaguuagc      540

guccucaccu ucaaaguccu agaccucaaa aacuacaucg auaaacaacu acuccccauc      600

cuaaacaaac aaucaugcuc caucccaaac aucgaaaccg uaaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacacgugag uucuccguua acgccggcgu caccaccccc      720

gucucuacau acaugcucac caacuccgaa cuccuuuccc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguacaaa ucguccgaca acaaagcuac      840

uccaucaugu gcaucaucaa agaagaaguc cuugcauacg ucguucaacu accccucuac      900

ggcguaaucg acacucccug cuggaaacuc cacaccuccc cgcucugcac aaccaacacc      960

aaagaaggca gcaacaucug ccucacccga accgaccgcg gcugguacug cgauaacgcc     1020

ggauccgucu ccuucuuccc acaagcagaa acuugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacacucccc uccgaaguca accugugcaa cgucgacauc     1140

uucaacccaa aauacgacug caaaaucaug accucaaaaa ccgacgucuc aucuucuguc     1200

aucaccucuc ucggcgcuau cgucuccugc uauggcaaaa ccaaaugcac cgccuccaac     1260

aagaaccgcg gcauuaucaa gaccuucucc aacggcugcg acuacgucuc caauaagggc     1320

gucgacaccg ucucugucgg caacacccuu uacugcguaa acaaacaaga aggucaaucu     1380

cucuacguca aaggagaacc caucaucaac uucuacgacc cccuggucuu ccccuccgac     1440

gaguucgaug caucaaucuc ccaagucaac gaaaagauca accaaucucu cgcuuucauc     1500

cgcaaauccg acgaacuccu acacaacgua aacgccggca aauccaccac aaacaucaug     1560

aucaccacca uuaucauagu caucaucguc auccuccucu ccuuaaucgc cguuggccuc     1620

cuucucuacu gcaaagcccg auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  3802
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3802
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3803
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3803
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3804
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3804
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3805
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3805
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3806
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3806
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3807
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3807
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3808
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3808
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ugaaagcaaa cgcaauuacu acaauacuaa cagcaguaac cuuuugcuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa cuugcucagc agucucaaaa      300

ggcuaucuag gagcacuacg aacagguugg uauacuucag ucauaacaau agaauuauca      360

aacauaaaag aaauuaaaug uaacggaacu gacgcaaaag uaaaacucau caaacaagaa      420

cucgauaaau acaaaaacgc uguaaccgac uuacaacuac uaaugcaauc aacuccagca      480

acaggcuccg gauccgcaau augcaguggu guagcaguau gcaaaguccu acaccuagaa      540

ggagaaguaa auaagauaaa aucugcucua cuaucaacaa auaaagcagu ugucucccua      600

ucaaauggag ucucaguacu caccuucaaa guauuagacc ucaaaaacua cauagacaaa      660

caacuauuac caauacucaa caaacaaucc ugcuccaucc cuaacauaga aaccguaauc      720

gaauuucaac aaaaaaauaa cagacucuua gaaauaacua gagaauuuuc aguuaaugca      780

ggcgugacaa caccaguauc aacauauaug cuaacaaacu ccgaacuccu aucccuaaua      840

aacgacaugc caaucacaaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaaucgua      900

agacaacaau cauacucuau aaugugcaua auaaaagaag aaguacuggc cuacguagua      960

caauuaccac ucuacggagu aauagacacc ccaugcugga aacuccauac aucaccccua     1020

ugcacaacaa acacaaaaga aggauccaac auaugucuca cuagaacaga cagaggcugg     1080

uacugcgaca acgcuggauc cgucucauuc uucccccaag cagaaacaug uaaaguacaa     1140

ucuaauagag uauuuuguga cacaaugaac agccucacac uaccauccga agucaaccua     1200

uguaacguag auauauuuaa ucccaaauac gacugcaaaa uaaugacauc caaaacagau     1260

guaucaucau ccguuaucac cucacuagga gccauaguuu caugcuacgg aaaaacaaaa     1320

ugcacugcau cuaacaaaaa uagagguaua auaaaaacau uuuccaacgg cugcgacuac     1380

gucucaaaca aaggcguaga caccguauca guaggaaaua cauuauauug cguaaauaaa     1440

caagaaggcc aaucccuaua cguaaaagga gaacccauca uaaacuucua ugacccacuu     1500

guuuuccccu cagacgaauu ugacgccuca auaucacaag uaaaugaaaa aauaaaccaa     1560

ucucuugccu ucauuagaaa aucagacgaa uuacuacaca acgucaacgc aggaaaauca     1620

acaacaaaca ucaugauaac aacgauaaua auagucauaa uaguaauacu acuaucauua     1680

aucgcagucg gacuccuauu auauugcaaa gcuagauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3809
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3809
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uaaaagccaa cgccauaacc accauccuca ccgcaguaac uuucugcuuc      240

gcuuccggcc aaaacaucac cgaagaauuu uaccaaagua ccugcagcgc agucucaaaa      300

ggauaccuag gcgcccuacg cacaggcugg uacaccuccg ucauuaccau cgaacucucc      360

aacaucaaag aaauuaaaug caacgguaca gacgcaaaag ucaaacucau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgac cuccaacucc ucaugcaauc cacccccgcc      480

acaggcucug gcuccgccau cugcucaggc guagcagucu gcaaaguccu gcaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cucuccacca acaaggccgu cguaucccuc      600

ucaaacggag uuagcguccu caccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuacucc ccauccuaaa caaacaauca ugcuccaucc caaacaucga aaccguaauc      720

gaguuccaac aaaagaacaa ccgccuccuc gaaaucacac gugaguucuc cguuaacgcc      780

ggcgucacca cccccgucuc uacauacaug cucaccaacu ccgaacuccu uucccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaaucguc      900

cgacaacaaa gcuacuccau caugugcauc aucaaagaag aaguccuugc auacgucguu      960

caacuacccc ucuacggcgu aaucgacacu cccugcugga aacuccacac cuccccgcuc     1020

ugcacaacca acaccaaaga aggcagcaac aucugccuca cccgaaccga ccgcggcugg     1080

uacugcgaua acgccggauc cgucuccuuc uucccacaag cagaaacuug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucacac uccccuccga agucaaccug     1200

ugcaacgucg acaucuucaa cccaaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

gucucaucuu cugucaucac cucucucggc gcuaucgucu ccugcuaugg caaaaccaaa     1320

ugcaccgccu ccaacaagaa ccgcggcauu aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaua agggcgucga caccgucucu gucggcaaca cccuuuacug cguaaacaaa     1440

caagaagguc aaucucucua cgucaaagga gaacccauca ucaacuucua cgacccccug     1500

gucuuccccu ccgacgaguu cgaugcauca aucucccaag ucaacgaaaa gaucaaccaa     1560

ucucucgcuu ucauccgcaa auccgacgaa cuccuacaca acguaaacgc cggcaaaucc     1620

accacaaaca ucaugaucac caccauuauc auagucauca ucgucauccu ccucuccuua     1680

aucgccguug gccuccuucu cuacugcaaa gcccgauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  3810
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3810
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3811
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3811
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3812
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3812
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3813
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3813
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3814
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3814
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3815
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3815
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3816
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3816
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ugaaagcaaa cgcaauuacu acaauacuaa cagcaguaac cuuuugcuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa cuugcucagc agucucaaaa      300

ggcuaucuag gagcacuacg aacagguugg uauacuucag ucauaacaau agaauuauca      360

aacauaaaag aaauuaaaug uaacggaacu gacgcaaaag uaaaacucau caaacaagaa      420

cucgauaaau acaaaaacgc uguaaccgac uuacaacuac uaaugcaauc aacuccagca      480

acaggcuccg gauccgcaau augcaguggu guagcaguau gcaaaguccu acaccuagaa      540

ggagaaguaa auaagauaaa aucugcucua cuaucaacaa auaaagcagu ugucucccua      600

ucaaauggag ucucaguacu caccuucaaa guauuagacc ucaaaaacua cauagacaaa      660

caacuauuac caauacucaa caaacaaucc ugcuccaucc cuaacauaga aaccguaauc      720

gaauuucaac aaaaaaauaa cagacucuua gaaauaacua gagaauuuuc aguuaaugca      780

ggcgugacaa caccaguauc aacauauaug cuaacaaacu ccgaacuccu aucccuaaua      840

aacgacaugc caaucacaaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaaucgua      900

agacaacaau cauacucuau aaugugcaua auaaaagaag aaguacuggc cuacguagua      960

caauuaccac ucuacggagu aauagacacc ccaugcugga aacuccauac aucaccccua     1020

ugcacaacaa acacaaaaga aggauccaac auaugucuca cuagaacaga cagaggcugg     1080

uacugcgaca acgcuggauc cgucucauuc uucccccaag cagaaacaug uaaaguacaa     1140

ucuaauagag uauuuuguga cacaaugaac agccucacac uaccauccga agucaaccua     1200

uguaacguag auauauuuaa ucccaaauac gacugcaaaa uaaugacauc caaaacagau     1260

guaucaucau ccguuaucac cucacuagga gccauaguuu caugcuacgg aaaaacaaaa     1320

ugcacugcau cuaacaaaaa uagagguaua auaaaaacau uuuccaacgg cugcgacuac     1380

gucucaaaca aaggcguaga caccguauca guaggaaaua cauuauauug cguaaauaaa     1440

caagaaggcc aaucccuaua cguaaaagga gaacccauca uaaacuucua ugacccacuu     1500

guuuuccccu cagacgaauu ugacgccuca auaucacaag uaaaugaaaa aauaaaccaa     1560

ucucuugccu ucauuagaaa aucagacgaa uuacuacaca acgucaacgc aggaaaauca     1620

acaacaaaca ucaugauaac aacgauaaua auagucauaa uaguaauacu acuaucauua     1680

aucgcagucg gacuccuauu auauugcaaa gcuagauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3817
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3817
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uaaaagccaa cgccauaacc accauccuca ccgcaguaac uuucugcuuc      240

gcuuccggcc aaaacaucac cgaagaauuu uaccaaagua ccugcagcgc agucucaaaa      300

ggauaccuag gcgcccuacg cacaggcugg uacaccuccg ucauuaccau cgaacucucc      360

aacaucaaag aaauuaaaug caacgguaca gacgcaaaag ucaaacucau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgac cuccaacucc ucaugcaauc cacccccgcc      480

acaggcucug gcuccgccau cugcucaggc guagcagucu gcaaaguccu gcaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cucuccacca acaaggccgu cguaucccuc      600

ucaaacggag uuagcguccu caccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuacucc ccauccuaaa caaacaauca ugcuccaucc caaacaucga aaccguaauc      720

gaguuccaac aaaagaacaa ccgccuccuc gaaaucacac gugaguucuc cguuaacgcc      780

ggcgucacca cccccgucuc uacauacaug cucaccaacu ccgaacuccu uucccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaaucguc      900

cgacaacaaa gcuacuccau caugugcauc aucaaagaag aaguccuugc auacgucguu      960

caacuacccc ucuacggcgu aaucgacacu cccugcugga aacuccacac cuccccgcuc     1020

ugcacaacca acaccaaaga aggcagcaac aucugccuca cccgaaccga ccgcggcugg     1080

uacugcgaua acgccggauc cgucuccuuc uucccacaag cagaaacuug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucacac uccccuccga agucaaccug     1200

ugcaacgucg acaucuucaa cccaaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

gucucaucuu cugucaucac cucucucggc gcuaucgucu ccugcuaugg caaaaccaaa     1320

ugcaccgccu ccaacaagaa ccgcggcauu aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaua agggcgucga caccgucucu gucggcaaca cccuuuacug cguaaacaaa     1440

caagaagguc aaucucucua cgucaaagga gaacccauca ucaacuucua cgacccccug     1500

gucuuccccu ccgacgaguu cgaugcauca aucucccaag ucaacgaaaa gaucaaccaa     1560

ucucucgcuu ucauccgcaa auccgacgaa cuccuacaca acguaaacgc cggcaaaucc     1620

accacaaaca ucaugaucac caccauuauc auagucauca ucgucauccu ccucuccuua     1680

aucgccguug gccuccuucu cuacugcaaa gcccgauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  3818
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3818
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3819
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3819
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cugcuccggc guggccgugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcgcug cuguccacca acaaggccgu ggucagccuc      600

uccaacggcg ugagcgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagucc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cucaccaacu ccgagcugcu gagccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcucccgc uguacggcgu gaucgacacg cccugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggguccaac aucugccuga cccgcaccga ccggggcugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ucccguccga ggucaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccucuacug cgucaacaag     1440

caggagggcc agagccugua cgugaagggg gagcccauca ucaacuucua cgacccccug     1500

guguucccga gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc gggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg ggcuccugcu guacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3820
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3820
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3821
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3821
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cuguucaggc guggcagucu gcaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcccug cugaguacga acaaagcugu ggucucccuc      600

ucuaaugggg ugagcguauu aacuuuuaag guucuggauc uuaagaacua caucgacaaa      660

caauugcugc cuauucuaaa uaagcagucc uguucaaucc caaacauaga aaccgugauu      720

gaguuccagc agaaaaauaa caggcuccug gaaaucacac gggaguuuag ugucaaugcc      780

ggagugacua ccccggugag cacauauaug cuuaccaacu cugagcuguu gucccucauu      840

aaugauaugc ccaucacgaa cgaccaaaag aaacugaugu caaacaaugu ccagaucguu      900

cgccagcaga gcuacaguau uaugugcaua aucaaggaag agguguuagc guauguagug      960

caacugccuc ucuacggcgu cauugauacu ccauguugga aacuucauac aucuccccug     1020

ugcaccacua acacaaagga aggcuccaau aucuguuuga cccgaacgga ccgugggugg     1080

uacugcgaua acgcaggaag cgugucguuc uuuccucagg ccgagaccug uaagguucag     1140

ucuaauagag uguucugcga cacaaugaac ucccuaacuc ugccaucaga agucaaucuc     1200

ugcaacgugg auauauuuaa ucccaaauau gacuguaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccugggu gcuaucgugu caugcuacgg caagaccaaa     1320

uguacagcca guaacaagaa uagggggauu aucaagaccu ucuccaacgg augcgacuau     1380

gucagcaaua aaggcgugga cacugucucu guggguaaca cgcuuuacug uguuaauaag     1440

caagaggggc agucacugua ugugaaagga gagccuauua uaaacuuuua cgauccauug     1500

guauucccga gugacgaauu ugaugcaagc aucucccagg ucaacgagaa gauuaaucag     1560

ucucucgcuu ucauccggaa aucggacgaa cuguuacaca acgugaaugc cggcaagagc     1620

acaaccaaca ucaugauuac uaccauaauc auuguuauca uugugauccu gcuaucccuc     1680

auagcggucg gccugcuuuu guauugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3822
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3822
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3823
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3823
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cuguagcggg gucgccgugu gcaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcgcuu cugagcacca acaaagccgu cgugucucuc      600

uccaauggcg uuagcgugcu gacauuuaag guccuugauc ugaagaacua caucgacaaa      660

caacuccugc cuauucugaa uaagcagucu uguuccaucc cgaacauuga aaccgugauc      720

gaguuccagc agaaaaauaa ccggcuccug gaaaucacgc gcgaguuuag cgugaaugcu      780

ggcgucacaa cccccguuuc uacauauaug cuuaccaacu ccgagcugcu cagccugauu      840

aaugauaugc cuaucaccaa cgaccaaaag aaacuuaugu ccaacaaugu gcagauugug      900

agacagcagu cuuacagcau caugugcauu aucaaggaag agguccuggc cuaugugguu      960

caacuccccc uguacggggu gaucgauaca ccuuguugga aacugcauac gagcccccuc     1020

ugcaccacaa acaccaagga aggauccaau auuugucuga cacggaccga ccgcggcugg     1080

uacugcgaua acgcuggguc ugucuccuuc uuuccucagg ccgagacgug uaaggugcag     1140

agcaauagag uuuucugcga cacaaugaac ucucuuaccc ugccgagcga agugaaucuc     1200

ugcaacgucg auaucuuuaa ucccaaauau gacuguaaga uuaugaccuc caaaacagau     1260

gugucuagcu ccgucaucac cagccuggga gcgauugugu cuugcuacgg caagacaaaa     1320

uguacggccu ccaacaagaa ucgggggauc aucaagaccu ucagcaacgg augcgacuau     1380

guuucuaaua aaggcgugga cacagucucc gugggcaaca cccuuuacug uguuaauaag     1440

caagaggggc agagccugua ugugaaagga gagccuauua ucaacuuuua cgauccccuc     1500

gucuucccuu ccgacgaauu ugaugcuucu auuagccagg ugaacgagaa gaucaaucag     1560

ucccuggccu ucauucgcaa aucugacgaa cugcuccaca acgugaaugc uggcaagagc     1620

acaaccaaca ucaugauuac gaccaucauc auuguuauca uugucauccu gcuuucccug     1680

auugccgugg ggcuccugcu guauugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3824
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3824
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ugaaagcaaa cgcaauuacu acaauacuaa cagcaguaac cuuuugcuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa cuugcucagc agucucaaaa      300

ggcuaucuag gagcacuacg aacagguugg uauacuucag ucauaacaau agaauuauca      360

aacauaaaag aaauuaaaug uaacggaacu gacgcaaaag uaaaacucau caaacaagaa      420

cucgauaaau acaaaaacgc uguaaccgac uuacaacuac uaaugcaauc aacuccagca      480

acaggcuccg gauccgcaau augcaguggu guagcaguau gcaaaguccu acaccuagaa      540

ggagaaguaa auaagauaaa aucugcucua cuaucaacaa auaaagcagu ugucucccua      600

ucaaauggag ucucaguacu caccuucaaa guauuagacc ucaaaaacua cauagacaaa      660

caacuauuac caauacucaa caaacaaucc ugcuccaucc cuaacauaga aaccguaauc      720

gaauuucaac aaaaaaauaa cagacucuua gaaauaacua gagaauuuuc aguuaaugca      780

ggcgugacaa caccaguauc aacauauaug cuaacaaacu ccgaacuccu aucccuaaua      840

aacgacaugc caaucacaaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaaucgua      900

agacaacaau cauacucuau aaugugcaua auaaaagaag aaguacuggc cuacguagua      960

caauuaccac ucuacggagu aauagacacc ccaugcugga aacuccauac aucaccccua     1020

ugcacaacaa acacaaaaga aggauccaac auaugucuca cuagaacaga cagaggcugg     1080

uacugcgaca acgcuggauc cgucucauuc uucccccaag cagaaacaug uaaaguacaa     1140

ucuaauagag uauuuuguga cacaaugaac agccucacac uaccauccga agucaaccua     1200

uguaacguag auauauuuaa ucccaaauac gacugcaaaa uaaugacauc caaaacagau     1260

guaucaucau ccguuaucac cucacuagga gccauaguuu caugcuacgg aaaaacaaaa     1320

ugcacugcau cuaacaaaaa uagagguaua auaaaaacau uuuccaacgg cugcgacuac     1380

gucucaaaca aaggcguaga caccguauca guaggaaaua cauuauauug cguaaauaaa     1440

caagaaggcc aaucccuaua cguaaaagga gaacccauca uaaacuucua ugacccacuu     1500

guuuuccccu cagacgaauu ugacgccuca auaucacaag uaaaugaaaa aauaaaccaa     1560

ucucuugccu ucauuagaaa aucagacgaa uuacuacaca acgucaacgc aggaaaauca     1620

acaacaaaca ucaugauaac aacgauaaua auagucauaa uaguaauacu acuaucauua     1680

aucgcagucg gacuccuauu auauugcaaa gcuagauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3825
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3825
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uaaaagccaa cgccauaacc accauccuca ccgcaguaac uuucugcuuc      240

gcuuccggcc aaaacaucac cgaagaauuu uaccaaagua ccugcagcgc agucucaaaa      300

ggauaccuag gcgcccuacg cacaggcugg uacaccuccg ucauuaccau cgaacucucc      360

aacaucaaag aaauuaaaug caacgguaca gacgcaaaag ucaaacucau caaacaagaa      420

cucgacaaau acaaaaacgc agucaccgac cuccaacucc ucaugcaauc cacccccgcc      480

acaggcucug gcuccgccau cugcucaggc guagcagucu gcaaaguccu gcaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cucuccacca acaaggccgu cguaucccuc      600

ucaaacggag uuagcguccu caccuucaaa guccuagacc ucaaaaacua caucgauaaa      660

caacuacucc ccauccuaaa caaacaauca ugcuccaucc caaacaucga aaccguaauc      720

gaguuccaac aaaagaacaa ccgccuccuc gaaaucacac gugaguucuc cguuaacgcc      780

ggcgucacca cccccgucuc uacauacaug cucaccaacu ccgaacuccu uucccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu acaaaucguc      900

cgacaacaaa gcuacuccau caugugcauc aucaaagaag aaguccuugc auacgucguu      960

caacuacccc ucuacggcgu aaucgacacu cccugcugga aacuccacac cuccccgcuc     1020

ugcacaacca acaccaaaga aggcagcaac aucugccuca cccgaaccga ccgcggcugg     1080

uacugcgaua acgccggauc cgucuccuuc uucccacaag cagaaacuug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucccucacac uccccuccga agucaaccug     1200

ugcaacgucg acaucuucaa cccaaaauac gacugcaaaa ucaugaccuc aaaaaccgac     1260

gucucaucuu cugucaucac cucucucggc gcuaucgucu ccugcuaugg caaaaccaaa     1320

ugcaccgccu ccaacaagaa ccgcggcauu aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaua agggcgucga caccgucucu gucggcaaca cccuuuacug cguaaacaaa     1440

caagaagguc aaucucucua cgucaaagga gaacccauca ucaacuucua cgacccccug     1500

gucuuccccu ccgacgaguu cgaugcauca aucucccaag ucaacgaaaa gaucaaccaa     1560

ucucucgcuu ucauccgcaa auccgacgaa cuccuacaca acguaaacgc cggcaaaucc     1620

accacaaaca ucaugaucac caccauuauc auagucauca ucgucauccu ccucuccuua     1680

aucgccguug gccuccuucu cuacugcaaa gcccgauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3826
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3826
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3827
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3827
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucugcucc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcg cugcugucca ccaacaaggc cguggucagc      480

cucuccaacg gcgugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cgcuguacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccucua cugcgucaac     1320

aagcaggagg gccagagccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1380

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcgggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3828
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3828
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3829
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3829
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucuguuca ggcguggcag ucugcaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcc cugcugagua cgaacaaagc uguggucucc      480

cucucuaaug gggugagcgu auuaacuuuu aagguucugg aucuuaagaa cuacaucgac      540

aaacaauugc ugccuauucu aaauaagcag uccuguucaa ucccaaacau agaaaccgug      600

auugaguucc agcagaaaaa uaacaggcuc cuggaaauca cacgggaguu uagugucaau      660

gccggaguga cuaccccggu gagcacauau augcuuacca acucugagcu guugucccuc      720

auuaaugaua ugcccaucac gaacgaccaa aagaaacuga ugucaaacaa uguccagauc      780

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcguaugua      840

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc      900

cugugcacca cuaacacaaa ggaaggcucc aauaucuguu ugacccgaac ggaccguggg      960

ugguacugcg auaacgcagg aagcgugucg uucuuuccuc aggccgagac cuguaagguu     1020

cagucuaaua gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1080

cucugcaacg uggauauauu uaaucccaaa uaugacugua agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccug ggugcuaucg ugucaugcua cggcaagacc     1200

aaauguacag ccaguaacaa gaauaggggg auuaucaaga ccuucuccaa cggaugcgac     1260

uaugucagca auaaaggcgu ggacacuguc ucugugggua acacgcuuua cuguguuaau     1320

aagcaagagg ggcagucacu guaugugaaa ggagagccua uuauaaacuu uuacgaucca     1380

uugguauucc cgagugacga auuugaugca agcaucuccc aggucaacga gaagauuaau     1440

cagucucucg cuuucauccg gaaaucggac gaacuguuac acaacgugaa ugccggcaag     1500

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1560

cucauagcgg ucggccugcu uuuguauugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3830
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3830
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3831
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3831
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucuguagc ggggucgccg ugugcaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcg cuucugagca ccaacaaagc cgucgugucu      480

cucuccaaug gcguuagcgu gcugacauuu aagguccuug aucugaagaa cuacaucgac      540

aaacaacucc ugccuauucu gaauaagcag ucuuguucca ucccgaacau ugaaaccgug      600

aucgaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uagcgugaau      660

gcuggcguca caacccccgu uucuacauau augcuuacca acuccgagcu gcucagccug      720

auuaaugaua ugccuaucac caacgaccaa aagaaacuua uguccaacaa ugugcagauu      780

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggccuaugug      840

guucaacucc cccuguacgg ggugaucgau acaccuuguu ggaaacugca uacgagcccc      900

cucugcacca caaacaccaa ggaaggaucc aauauuuguc ugacacggac cgaccgcggc      960

ugguacugcg auaacgcugg gucugucucc uucuuuccuc aggccgagac guguaaggug     1020

cagagcaaua gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1080

cucugcaacg ucgauaucuu uaaucccaaa uaugacugua agauuaugac cuccaaaaca     1140

gaugugucua gcuccgucau caccagccug ggagcgauug ugucuugcua cggcaagaca     1200

aaauguacgg ccuccaacaa gaaucggggg aucaucaaga ccuucagcaa cggaugcgac     1260

uauguuucua auaaaggcgu ggacacaguc uccgugggca acacccuuua cuguguuaau     1320

aagcaagagg ggcagagccu guaugugaaa ggagagccua uuaucaacuu uuacgauccc     1380

cucgucuucc cuuccgacga auuugaugcu ucuauuagcc aggugaacga gaagaucaau     1440

cagucccugg ccuucauucg caaaucugac gaacugcucc acaacgugaa ugcuggcaag     1500

agcacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1560

cugauugccg uggggcuccu gcuguauugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3832
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3832
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaauuacuaa uccugaaagc aaacgcaauu acuacaauac uaacagcagu aaccuuuugc      120

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacuugcuc agcagucuca      180

aaaggcuauc uaggagcacu acgaacaggu ugguauacuu cagucauaac aauagaauua      240

ucaaacauaa aagaaauuaa auguaacgga acugacgcaa aaguaaaacu caucaaacaa      300

gaacucgaua aauacaaaaa cgcuguaacc gacuuacaac uacuaaugca aucaacucca      360

gcaacaggcu ccggauccgc aauaugcagu gguguagcag uaugcaaagu ccuacaccua      420

gaaggagaag uaaauaagau aaaaucugcu cuacuaucaa caaauaaagc aguugucucc      480

cuaucaaaug gagucucagu acucaccuuc aaaguauuag accucaaaaa cuacauagac      540

aaacaacuau uaccaauacu caacaaacaa uccugcucca ucccuaacau agaaaccgua      600

aucgaauuuc aacaaaaaaa uaacagacuc uuagaaauaa cuagagaauu uucaguuaau      660

gcaggcguga caacaccagu aucaacauau augcuaacaa acuccgaacu ccuaucccua      720

auaaacgaca ugccaaucac aaacgaccaa aaaaaacuaa uguccaacaa cguacaaauc      780

guaagacaac aaucauacuc uauaaugugc auaauaaaag aagaaguacu ggccuacgua      840

guacaauuac cacucuacgg aguaauagac accccaugcu ggaaacucca uacaucaccc      900

cuaugcacaa caaacacaaa agaaggaucc aacauauguc ucacuagaac agacagaggc      960

ugguacugcg acaacgcugg auccgucuca uucuuccccc aagcagaaac auguaaagua     1020

caaucuaaua gaguauuuug ugacacaaug aacagccuca cacuaccauc cgaagucaac     1080

cuauguaacg uagauauauu uaaucccaaa uacgacugca aaauaaugac auccaaaaca     1140

gauguaucau cauccguuau caccucacua ggagccauag uuucaugcua cggaaaaaca     1200

aaaugcacug caucuaacaa aaauagaggu auaauaaaaa cauuuuccaa cggcugcgac     1260

uacgucucaa acaaaggcgu agacaccgua ucaguaggaa auacauuaua uugcguaaau     1320

aaacaagaag gccaaucccu auacguaaaa ggagaaccca ucauaaacuu cuaugaccca     1380

cuuguuuucc ccucagacga auuugacgcc ucaauaucac aaguaaauga aaaaauaaac     1440

caaucucuug ccuucauuag aaaaucagac gaauuacuac acaacgucaa cgcaggaaaa     1500

ucaacaacaa acaucaugau aacaacgaua auaauaguca uaauaguaau acuacuauca     1560

uuaaucgcag ucggacuccu auuauauugc aaagcuagau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3833
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3833
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuca uacuaaaagc caacgccaua accaccaucc ucaccgcagu aacuuucugc      120

uucgcuuccg gccaaaacau caccgaagaa uuuuaccaaa guaccugcag cgcagucuca      180

aaaggauacc uaggcgcccu acgcacaggc ugguacaccu ccgucauuac caucgaacuc      240

uccaacauca aagaaauuaa augcaacggu acagacgcaa aagucaaacu caucaaacaa      300

gaacucgaca aauacaaaaa cgcagucacc gaccuccaac uccucaugca auccaccccc      360

gccacaggcu cuggcuccgc caucugcuca ggcguagcag ucugcaaagu ccugcaccuc      420

gaaggcgaag ucaacaaaau caagucagcc cuccucucca ccaacaaggc cgucguaucc      480

cucucaaacg gaguuagcgu ccucaccuuc aaaguccuag accucaaaaa cuacaucgau      540

aaacaacuac uccccauccu aaacaaacaa ucaugcucca ucccaaacau cgaaaccgua      600

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cacgugaguu cuccguuaac      660

gccggcguca ccacccccgu cucuacauac augcucacca acuccgaacu ccuuucccuc      720

aucaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguacaaauc      780

guccgacaac aaagcuacuc caucaugugc aucaucaaag aagaaguccu ugcauacguc      840

guucaacuac cccucuacgg cguaaucgac acucccugcu ggaaacucca caccuccccg      900

cucugcacaa ccaacaccaa agaaggcagc aacaucugcc ucacccgaac cgaccgcggc      960

ugguacugcg auaacgccgg auccgucucc uucuucccac aagcagaaac uugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucccuca cacuccccuc cgaagucaac     1080

cugugcaacg ucgacaucuu caacccaaaa uacgacugca aaaucaugac cucaaaaacc     1140

gacgucucau cuucugucau caccucucuc ggcgcuaucg ucuccugcua uggcaaaacc     1200

aaaugcaccg ccuccaacaa gaaccgcggc auuaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca auaagggcgu cgacaccguc ucugucggca acacccuuua cugcguaaac     1320

aaacaagaag gucaaucucu cuacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1380

cuggucuucc ccuccgacga guucgaugca ucaaucuccc aagucaacga aaagaucaac     1440

caaucucucg cuuucauccg caaauccgac gaacuccuac acaacguaaa cgccggcaaa     1500

uccaccacaa acaucaugau caccaccauu aucauaguca ucaucgucau ccuccucucc     1560

uuaaucgccg uuggccuccu ucucuacugc aaagcccgau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  3834
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3834
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3835
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3835
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc ugcuccggcg uggccgugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcgcugc uguccaccaa caaggccgug gucagccucu      480

ccaacggcgu gagcgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug agccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccgcu guacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac cggggcuggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag gucaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccucuacugc gucaacaagc     1320

aggagggcca gagccuguac gugaaggggg agcccaucau caacuucuac gacccccugg     1380

uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg gcuccugcug uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3836
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3836
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3837
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3837
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua aagcaggaac      300

ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuauc uguucaggcg uggcagucug caagguguug caccucgagg      420

gugagguuaa uaaaauuaag agcgcccugc ugaguacgaa caaagcugug gucucccucu      480

cuaauggggu gagcguauua acuuuuaagg uucuggaucu uaagaacuac aucgacaaac      540

aauugcugcc uauucuaaau aagcaguccu guucaauccc aaacauagaa accgugauug      600

aguuccagca gaaaaauaac aggcuccugg aaaucacacg ggaguuuagu gucaaugccg      660

gagugacuac cccggugagc acauauaugc uuaccaacuc ugagcuguug ucccucauua      720

augauaugcc caucacgaac gaccaaaaga aacugauguc aaacaauguc cagaucguuc      780

gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagcg uauguagugc      840

aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca ucuccccugu      900

gcaccacuaa cacaaaggaa ggcuccaaua ucuguuugac ccgaacggac cguggguggu      960

acugcgauaa cgcaggaagc gugucguucu uuccucaggc cgagaccugu aagguucagu     1020

cuaauagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa gucaaucucu     1080

gcaacgugga uauauuuaau cccaaauaug acuguaagau uaugaccagu aaaacagaug     1140

uaagcuccuc uguuaucacu agccugggug cuaucguguc augcuacggc aagaccaaau     1200

guacagccag uaacaagaau agggggauua ucaagaccuu cuccaacgga ugcgacuaug     1260

ucagcaauaa aggcguggac acugucucug uggguaacac gcuuuacugu guuaauaagc     1320

aagaggggca gucacuguau gugaaaggag agccuauuau aaacuuuuac gauccauugg     1380

uauucccgag ugacgaauuu gaugcaagca ucucccaggu caacgagaag auuaaucagu     1440

cucucgcuuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcc ggcaagagca     1500

caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug cuaucccuca     1560

uagcggucgg ccugcuuuug uauugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3838
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3838
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3839
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3839
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu aagcaggaac      300

uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauc uguagcgggg ucgccgugug caagguucuc caccuggagg      420

gagaggugaa uaaaauuaag uccgcgcuuc ugagcaccaa caaagccguc gugucucucu      480

ccaauggcgu uagcgugcug acauuuaagg uccuugaucu gaagaacuac aucgacaaac      540

aacuccugcc uauucugaau aagcagucuu guuccauccc gaacauugaa accgugaucg      600

aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuagc gugaaugcug      660

gcgucacaac ccccguuucu acauauaugc uuaccaacuc cgagcugcuc agccugauua      720

augauaugcc uaucaccaac gaccaaaaga aacuuauguc caacaaugug cagauuguga      780

gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcc uaugugguuc      840

aacucccccu guacggggug aucgauacac cuuguuggaa acugcauacg agcccccucu      900

gcaccacaaa caccaaggaa ggauccaaua uuugucugac acggaccgac cgcggcuggu      960

acugcgauaa cgcugggucu gucuccuucu uuccucaggc cgagacgugu aaggugcaga     1020

gcaauagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa gugaaucucu     1080

gcaacgucga uaucuuuaau cccaaauaug acuguaagau uaugaccucc aaaacagaug     1140

ugucuagcuc cgucaucacc agccugggag cgauuguguc uugcuacggc aagacaaaau     1200

guacggccuc caacaagaau cgggggauca ucaagaccuu cagcaacgga ugcgacuaug     1260

uuucuaauaa aggcguggac acagucuccg ugggcaacac ccuuuacugu guuaauaagc     1320

aagaggggca gagccuguau gugaaaggag agccuauuau caacuuuuac gauccccucg     1380

ucuucccuuc cgacgaauuu gaugcuucua uuagccaggu gaacgagaag aucaaucagu     1440

cccuggccuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcu ggcaagagca     1500

caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug cuuucccuga     1560

uugccguggg gcuccugcug uauugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3840
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3840
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaau       60

uacuaauccu gaaagcaaac gcaauuacua caauacuaac agcaguaacc uuuugcuuug      120

ccucaggaca aaacauaacu gaagaauuuu accaaucaac uugcucagca gucucaaaag      180

gcuaucuagg agcacuacga acagguuggu auacuucagu cauaacaaua gaauuaucaa      240

acauaaaaga aauuaaaugu aacggaacug acgcaaaagu aaaacucauc aaacaagaac      300

ucgauaaaua caaaaacgcu guaaccgacu uacaacuacu aaugcaauca acuccagcaa      360

caggcuccgg auccgcaaua ugcaguggug uagcaguaug caaaguccua caccuagaag      420

gagaaguaaa uaagauaaaa ucugcucuac uaucaacaaa uaaagcaguu gucucccuau      480

caaauggagu cucaguacuc accuucaaag uauuagaccu caaaaacuac auagacaaac      540

aacuauuacc aauacucaac aaacaauccu gcuccauccc uaacauagaa accguaaucg      600

aauuucaaca aaaaaauaac agacucuuag aaauaacuag agaauuuuca guuaaugcag      660

gcgugacaac accaguauca acauauaugc uaacaaacuc cgaacuccua ucccuaauaa      720

acgacaugcc aaucacaaac gaccaaaaaa aacuaauguc caacaacgua caaaucguaa      780

gacaacaauc auacucuaua augugcauaa uaaaagaaga aguacuggcc uacguaguac      840

aauuaccacu cuacggagua auagacaccc caugcuggaa acuccauaca ucaccccuau      900

gcacaacaaa cacaaaagaa ggauccaaca uaugucucac uagaacagac agaggcuggu      960

acugcgacaa cgcuggaucc gucucauucu ucccccaagc agaaacaugu aaaguacaau     1020

cuaauagagu auuuugugac acaaugaaca gccucacacu accauccgaa gucaaccuau     1080

guaacguaga uauauuuaau cccaaauacg acugcaaaau aaugacaucc aaaacagaug     1140

uaucaucauc cguuaucacc ucacuaggag ccauaguuuc augcuacgga aaaacaaaau     1200

gcacugcauc uaacaaaaau agagguauaa uaaaaacauu uuccaacggc ugcgacuacg     1260

ucucaaacaa aggcguagac accguaucag uaggaaauac auuauauugc guaaauaaac     1320

aagaaggcca aucccuauac guaaaaggag aacccaucau aaacuucuau gacccacuug     1380

uuuuccccuc agacgaauuu gacgccucaa uaucacaagu aaaugaaaaa auaaaccaau     1440

cucuugccuu cauuagaaaa ucagacgaau uacuacacaa cgucaacgca ggaaaaucaa     1500

caacaaacau caugauaaca acgauaauaa uagucauaau aguaauacua cuaucauuaa     1560

ucgcagucgg acuccuauua uauugcaaag cuagauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3841
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3841
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacucauacu aaaagccaac gccauaacca ccauccucac cgcaguaacu uucugcuucg      120

cuuccggcca aaacaucacc gaagaauuuu accaaaguac cugcagcgca gucucaaaag      180

gauaccuagg cgcccuacgc acaggcuggu acaccuccgu cauuaccauc gaacucucca      240

acaucaaaga aauuaaaugc aacgguacag acgcaaaagu caaacucauc aaacaagaac      300

ucgacaaaua caaaaacgca gucaccgacc uccaacuccu caugcaaucc acccccgcca      360

caggcucugg cuccgccauc ugcucaggcg uagcagucug caaaguccug caccucgaag      420

gcgaagucaa caaaaucaag ucagcccucc ucuccaccaa caaggccguc guaucccucu      480

caaacggagu uagcguccuc accuucaaag uccuagaccu caaaaacuac aucgauaaac      540

aacuacuccc cauccuaaac aaacaaucau gcuccauccc aaacaucgaa accguaaucg      600

aguuccaaca aaagaacaac cgccuccucg aaaucacacg ugaguucucc guuaacgccg      660

gcgucaccac ccccgucucu acauacaugc ucaccaacuc cgaacuccuu ucccucauca      720

acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacgua caaaucgucc      780

gacaacaaag cuacuccauc augugcauca ucaaagaaga aguccuugca uacgucguuc      840

aacuaccccu cuacggcgua aucgacacuc ccugcuggaa acuccacacc uccccgcucu      900

gcacaaccaa caccaaagaa ggcagcaaca ucugccucac ccgaaccgac cgcggcuggu      960

acugcgauaa cgccggaucc gucuccuucu ucccacaagc agaaacuugc aaaguccaau     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacacu ccccuccgaa gucaaccugu     1080

gcaacgucga caucuucaac ccaaaauacg acugcaaaau caugaccuca aaaaccgacg     1140

ucucaucuuc ugucaucacc ucucucggcg cuaucgucuc cugcuauggc aaaaccaaau     1200

gcaccgccuc caacaagaac cgcggcauua ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaauaa gggcgucgac accgucucug ucggcaacac ccuuuacugc guaaacaaac     1320

aagaagguca aucucucuac gucaaaggag aacccaucau caacuucuac gacccccugg     1380

ucuuccccuc cgacgaguuc gaugcaucaa ucucccaagu caacgaaaag aucaaccaau     1440

cucucgcuuu cauccgcaaa uccgacgaac uccuacacaa cguaaacgcc ggcaaaucca     1500

ccacaaacau caugaucacc accauuauca uagucaucau cgucauccuc cucuccuuaa     1560

ucgccguugg ccuccuucuc uacugcaaag cccgauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  3842
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1) R6775

<400>  3842
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3843
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt1)

<400>  3843
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucugcuccgg cguggccgug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcgcu gcuguccacc      420

aacaaggccg uggucagccu cuccaacggc gugagcgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcaguc cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcucaccaac      660

uccgagcugc ugagccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccg cuguacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggguccaa caucugccug      900

acccgcaccg accggggcug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cucccguccg aggucaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccucuacu gcgucaacaa gcaggagggc cagagccugu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccccu gguguucccg agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cgggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug gggcuccugc uguacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3844
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt2)

<400>  3844
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3845
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt3)

<400>  3845
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaucaaau gcaauggcac cgacgccaag      240

gugaaacuaa uaaagcagga acucgauaag uauaaaaacg caguaacuga ccugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua ucuguucagg cguggcaguc      360

ugcaaggugu ugcaccucga gggugagguu aauaaaauua agagcgcccu gcugaguacg      420

aacaaagcug uggucucccu cucuaauggg gugagcguau uaacuuuuaa gguucuggau      480

cuuaagaacu acaucgacaa acaauugcug ccuauucuaa auaagcaguc cuguucaauc      540

ccaaacauag aaaccgugau ugaguuccag cagaaaaaua acaggcuccu ggaaaucaca      600

cgggaguuua gugucaaugc cggagugacu accccgguga gcacauauau gcuuaccaac      660

ucugagcugu ugucccucau uaaugauaug cccaucacga acgaccaaaa gaaacugaug      720

ucaaacaaug uccagaucgu ucgccagcag agcuacagua uuaugugcau aaucaaggaa      780

gagguguuag cguauguagu gcaacugccu cucuacggcg ucauugauac uccauguugg      840

aaacuucaua caucuccccu gugcaccacu aacacaaagg aaggcuccaa uaucuguuug      900

acccgaacgg accgugggug guacugcgau aacgcaggaa gcgugucguu cuuuccucag      960

gccgagaccu guaagguuca gucuaauaga guguucugcg acacaaugaa cucccuaacu     1020

cugccaucag aagucaaucu cugcaacgug gauauauuua aucccaaaua ugacuguaag     1080

auuaugacca guaaaacaga uguaagcucc ucuguuauca cuagccuggg ugcuaucgug     1140

ucaugcuacg gcaagaccaa auguacagcc aguaacaaga auagggggau uaucaagacc     1200

uucuccaacg gaugcgacua ugucagcaau aaaggcgugg acacugucuc uguggguaac     1260

acgcuuuacu guguuaauaa gcaagagggg cagucacugu augugaaagg agagccuauu     1320

auaaacuuuu acgauccauu gguauucccg agugacgaau uugaugcaag caucucccag     1380

gucaacgaga agauuaauca gucucucgcu uucauccgga aaucggacga acuguuacac     1440

aacgugaaug ccggcaagag cacaaccaac aucaugauua cuaccauaau cauuguuauc     1500

auugugaucc ugcuaucccu cauagcgguc ggccugcuuu uguauugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3846
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt4)

<400>  3846
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3847
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt5)

<400>  3847
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaucaaau gcaaugggac cgacgccaag      240

gugaaacuua uuaagcagga acuggauaag uauaaaaacg cugugacgga ccuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua ucuguagcgg ggucgccgug      360

ugcaagguuc uccaccugga gggagaggug aauaaaauua aguccgcgcu ucugagcacc      420

aacaaagccg ucgugucucu cuccaauggc guuagcgugc ugacauuuaa gguccuugau      480

cugaagaacu acaucgacaa acaacuccug ccuauucuga auaagcaguc uuguuccauc      540

ccgaacauug aaaccgugau cgaguuccag cagaaaaaua accggcuccu ggaaaucacg      600

cgcgaguuua gcgugaaugc uggcgucaca acccccguuu cuacauauau gcuuaccaac      660

uccgagcugc ucagccugau uaaugauaug ccuaucacca acgaccaaaa gaaacuuaug      720

uccaacaaug ugcagauugu gagacagcag ucuuacagca ucaugugcau uaucaaggaa      780

gagguccugg ccuauguggu ucaacucccc cuguacgggg ugaucgauac accuuguugg      840

aaacugcaua cgagcccccu cugcaccaca aacaccaagg aaggauccaa uauuugucug      900

acacggaccg accgcggcug guacugcgau aacgcugggu cugucuccuu cuuuccucag      960

gccgagacgu guaaggugca gagcaauaga guuuucugcg acacaaugaa cucucuuacc     1020

cugccgagcg aagugaaucu cugcaacguc gauaucuuua aucccaaaua ugacuguaag     1080

auuaugaccu ccaaaacaga ugugucuagc uccgucauca ccagccuggg agcgauugug     1140

ucuugcuacg gcaagacaaa auguacggcc uccaacaaga aucgggggau caucaagacc     1200

uucagcaacg gaugcgacua uguuucuaau aaaggcgugg acacagucuc cgugggcaac     1260

acccuuuacu guguuaauaa gcaagagggg cagagccugu augugaaagg agagccuauu     1320

aucaacuuuu acgauccccu cgucuucccu uccgacgaau uugaugcuuc uauuagccag     1380

gugaacgaga agaucaauca gucccuggcc uucauucgca aaucugacga acugcuccac     1440

aacgugaaug cuggcaagag cacaaccaac aucaugauua cgaccaucau cauuguuauc     1500

auugucaucc ugcuuucccu gauugccgug gggcuccugc uguauugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3848
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt6)

<400>  3848
gggagaaagc uuaccaugga auuacuaauc cugaaagcaa acgcaauuac uacaauacua       60

acagcaguaa ccuuuugcuu ugccucagga caaaacauaa cugaagaauu uuaccaauca      120

acuugcucag cagucucaaa aggcuaucua ggagcacuac gaacagguug guauacuuca      180

gucauaacaa uagaauuauc aaacauaaaa gaaauuaaau guaacggaac ugacgcaaaa      240

guaaaacuca ucaaacaaga acucgauaaa uacaaaaacg cuguaaccga cuuacaacua      300

cuaaugcaau caacuccagc aacaggcucc ggauccgcaa uaugcagugg uguagcagua      360

ugcaaagucc uacaccuaga aggagaagua aauaagauaa aaucugcucu acuaucaaca      420

aauaaagcag uugucucccu aucaaaugga gucucaguac ucaccuucaa aguauuagac      480

cucaaaaacu acauagacaa acaacuauua ccaauacuca acaaacaauc cugcuccauc      540

ccuaacauag aaaccguaau cgaauuucaa caaaaaaaua acagacucuu agaaauaacu      600

agagaauuuu caguuaaugc aggcgugaca acaccaguau caacauauau gcuaacaaac      660

uccgaacucc uaucccuaau aaacgacaug ccaaucacaa acgaccaaaa aaaacuaaug      720

uccaacaacg uacaaaucgu aagacaacaa ucauacucua uaaugugcau aauaaaagaa      780

gaaguacugg ccuacguagu acaauuacca cucuacggag uaauagacac cccaugcugg      840

aaacuccaua caucaccccu augcacaaca aacacaaaag aaggauccaa cauaugucuc      900

acuagaacag acagaggcug guacugcgac aacgcuggau ccgucucauu cuucccccaa      960

gcagaaacau guaaaguaca aucuaauaga guauuuugug acacaaugaa cagccucaca     1020

cuaccauccg aagucaaccu auguaacgua gauauauuua aucccaaaua cgacugcaaa     1080

auaaugacau ccaaaacaga uguaucauca uccguuauca ccucacuagg agccauaguu     1140

ucaugcuacg gaaaaacaaa augcacugca ucuaacaaaa auagagguau aauaaaaaca     1200

uuuuccaacg gcugcgacua cgucucaaac aaaggcguag acaccguauc aguaggaaau     1260

acauuauauu gcguaaauaa acaagaaggc caaucccuau acguaaaagg agaacccauc     1320

auaaacuucu augacccacu uguuuucccc ucagacgaau uugacgccuc aauaucacaa     1380

guaaaugaaa aaauaaacca aucucuugcc uucauuagaa aaucagacga auuacuacac     1440

aacgucaacg caggaaaauc aacaacaaac aucaugauaa caacgauaau aauagucaua     1500

auaguaauac uacuaucauu aaucgcaguc ggacuccuau uauauugcaa agcuagauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3849
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut3 (opt11)

<400>  3849
gggagaaagc uuaccaugga acuacucaua cuaaaagcca acgccauaac caccauccuc       60

accgcaguaa cuuucugcuu cgcuuccggc caaaacauca ccgaagaauu uuaccaaagu      120

accugcagcg cagucucaaa aggauaccua ggcgcccuac gcacaggcug guacaccucc      180

gucauuacca ucgaacucuc caacaucaaa gaaauuaaau gcaacgguac agacgcaaaa      240

gucaaacuca ucaaacaaga acucgacaaa uacaaaaacg cagucaccga ccuccaacuc      300

cucaugcaau ccacccccgc cacaggcucu ggcuccgcca ucugcucagg cguagcaguc      360

ugcaaagucc ugcaccucga aggcgaaguc aacaaaauca agucagcccu ccucuccacc      420

aacaaggccg ucguaucccu cucaaacgga guuagcgucc ucaccuucaa aguccuagac      480

cucaaaaacu acaucgauaa acaacuacuc cccauccuaa acaaacaauc augcuccauc      540

ccaaacaucg aaaccguaau cgaguuccaa caaaagaaca accgccuccu cgaaaucaca      600

cgugaguucu ccguuaacgc cggcgucacc acccccgucu cuacauacau gcucaccaac      660

uccgaacucc uuucccucau caacgacaug ccaaucacca acgaccaaaa gaaacucaug      720

ucaaacaacg uacaaaucgu ccgacaacaa agcuacucca ucaugugcau caucaaagaa      780

gaaguccuug cauacgucgu ucaacuaccc cucuacggcg uaaucgacac ucccugcugg      840

aaacuccaca ccuccccgcu cugcacaacc aacaccaaag aaggcagcaa caucugccuc      900

acccgaaccg accgcggcug guacugcgau aacgccggau ccgucuccuu cuucccacaa      960

gcagaaacuu gcaaagucca auccaaccgc gucuucugcg acaccaugaa cucccucaca     1020

cuccccuccg aagucaaccu gugcaacguc gacaucuuca acccaaaaua cgacugcaaa     1080

aucaugaccu caaaaaccga cgucucaucu ucugucauca ccucucucgg cgcuaucguc     1140

uccugcuaug gcaaaaccaa augcaccgcc uccaacaaga accgcggcau uaucaagacc     1200

uucuccaacg gcugcgacua cgucuccaau aagggcgucg acaccgucuc ugucggcaac     1260

acccuuuacu gcguaaacaa acaagaaggu caaucucucu acgucaaagg agaacccauc     1320

aucaacuucu acgacccccu ggucuucccc uccgacgagu ucgaugcauc aaucucccaa     1380

gucaacgaaa agaucaacca aucucucgcu uucauccgca aauccgacga acuccuacac     1440

aacguaaacg ccggcaaauc caccacaaac aucaugauca ccaccauuau cauagucauc     1500

aucgucaucc uccucuccuu aaucgccguu ggccuccuuc ucuacugcaa agcccgauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  3850
<211>  535
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3850

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Ser 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Arg Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Tyr Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly Ile 
        515                 520                 525             


Asn Asn Ile Ala Phe Ser Asn 
    530                 535 


<210>  3851
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3851
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1560

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacuga                  1608


<210>  3852
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3852
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccaccg gcagcggguc cgccaucgcc agcggcgugg cggugugcaa gguccugcac      360

cucgagggcg aggugaacaa gaucaagucc gcccugcuga gcaccaacaa ggccgugguc      420

ucccucagca acgggguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccccugua cggggugauc gacacgccgu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      900

gggugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1020

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1140

accaagugca ccgccagcaa caagaaccgg ggcaucauca agaccuucuc caacgggugc     1200

gacuacguga gcaacaaggg cgucgacacg gugagcgugg gcaacacccu cuacuacguc     1260

aacaagcagg aggggaaguc ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguccacccc ggugacccug     1560

agcaaggacc agcucuccgg gaucaacaac aucgccuuca gcaacuga                  1608


<210>  3853
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3853
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1260

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1560

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacuga                  1608


<210>  3854
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3854
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccaccg gcucgggguc agcuauagca agcggagugg ccgucuguaa gguguugcac      360

cucgagggcg aaguuaacaa aaucaagagu gcucugcugu ccacgaauaa agccgugguc      420

ucucucagca acgguguguc cguauuaacu uuuaagguuc uggaccuuaa gaauuacauu      480

gauaaacaau ugcugccuau ccuaaacaag cagucaugca guauuagcaa uaucgagacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuucuguc      600

aacgcggggg ugacuacccc aguguccaca uauaugcuua ccaauucaga acuguugagc      660

cucaucaacg acaugccgau uacgaacgau caaaagaaac ugaugaguaa uaacguccag      720

aucguucgcc agcagucuua cuccaucaug uguauuauaa aggaggaagu guuagcauau      780

guagugcaac ugccccucua cggagucauc gacacuccuu gcuggaaacu ucauacaagc      840

ccacugugua ccacuaauac aaaggagggc ucgaacauuu gcuugacccg aacggaucgu      900

ggcugguacu gugacaaugc cgggucugug uccuucuuuc cccaggcuga aaccugcaag      960

guucagucaa acagaguguu cugugauaca augaauagua gaacucugcc uagcgagguc     1020

aaccucugca auguggacau cuuuaaccca aaauaugauu gcaagauaau gaccuccaaa     1080

acagacguau cuagcucagu uauuaccagu cugggagcca ucguguccug uuacgguaag     1140

acuaaaugca cagcaagcaa uaagaacagg ggcaucauua agaccuucuc uaaugggugu     1200

gauuaugucu caaacaaagg aguggacacu gucagugugg gcaauacgcu uuacuauguu     1260

aacaagcaag aggguaaaag ccuguacgug aagggggaac ccaucauuaa cuuuuaugac     1320

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa ugagaaaauc     1380

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcggga     1440

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcucuacacc ggugacccug     1560

agcaaggacc agcucuccgg cauaaacaau aucgcuuucu caaacuga                  1608


<210>  3855
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3855
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1560

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  3856
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3856
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacag ggucuggaag cgcuauugcc uccggcgucg cgguguguaa gguucuccac      360

cuggaggggg aagugaacaa aaucaagagc gcccuucugu cuaccaauaa agcugucgug      420

ucccucagca acggaguuuc ugugcugaca uuuaaggucc uugaccugaa gaauuacauu      480

gauaaacaac uccugccuau ccugaacaag caguccugca gcauuucuaa uaucgagacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuuccgug      600

aacgccggcg ucacaacccc gguuagcaca uauaugcuua ccaauuccga acugcucucu      660

cugaucaacg acaugcccau uaccaacgau caaaagaaac uuaugagcaa uaacgugcag      720

aucgugagac agcaguccua cagcauuaug uguaucauua aggaggaagu ccuggcuuau      780

gugguucaac ucccucugua cggcgugauc gacacacccu gcuggaaacu gcauacgucu      840

ccucucugua ccacaaauac caaggagggg uccaacaucu gccugacacg gaccgaucgc      900

ggaugguacu gugacaaugc cggcagcguc ucuuucuuuc cccaggcgga aacgugcaag      960

gugcagagca acagaguuuu cugugauaca augaacucca gaacccugcc uucugaggug     1020

aaucucugca augucgacau uuuuaacccg aaauaugauu gcaagaucau gaccagcaaa     1080

acagacgugu ccagcucugu cauuaccucc cugggggcca ucgugagcug uuacggaaag     1140

acaaaaugca cggcuucuaa uaagaaccgg ggcauuauca agaccuucuc caaugggugu     1200

gauuauguua gcaacaaagg aguggacaca gucuccgugg gcaauacccu uuacuauguu     1260

aacaagcaag agggcaaauc ucuguacgug aagggggaac ccaucauuaa cuuuuaugac     1320

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa ugagaaaauu     1380

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccgga     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucucugaucg ccgugggccu ccugcuguac ugcaaagcua gauccacacc ugugacccuu     1560

agcaaggacc agcucucugg gauuaacaau aucgcguucu ccaacuga                  1608


<210>  3857
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3857
auggaacuac uaauacuaaa agccaaugca auaacaacca uacuaaccgc cguaacauuu       60

uguuucgcau caggucaaaa cauaaccgaa gaauuuuauc aaucaacaug cucagcagua      120

ucaaaaggau acuuauccgc ucuaagaaca ggaugguaca caaguguaau uacaauagag      180

cucucaaaca uaaaagaaaa caaaugcaau ggaacugacg caaaaguuaa acuuauaaaa      240

caagaacuag auaaauauaa aaaugcagua accgaauuac aacuccuaau gcaauccaca      300

ccugcuaccg guuccggauc agccauagca ucuggaguag ccguaugcaa aguccuccac      360

cuagaaggag aaguaaauaa aaucaaauca gcacuauuau cuaccaauaa agcaguuguc      420

ucacuaucca auggcguauc aguacuaaca uucaaaguau uagaccuuaa aaacuacaua      480

gacaaacaac uauuaccaau ucugaacaaa caauccuguu caauaucaaa caucgaaacg      540

guaauagaau uucaacaaaa aaauaacaga uuacuugaaa uaacaagaga auuuucagua      600

aaugcaggag uuacaacacc cgucuccacc uacaugcuca caaauucaga auuauuauca      660

cuuauaaacg acaugccaau aacuaacgac caaaaaaaac uaaugucaaa caauguccaa      720

auaguccgac aacaauccua cucaauaaug ugcauuauaa aagaagaagu ccuagccuac      780

guuguccaac uacccuuaua uggaguaaua gauaccccau gcuggaaacu ucauaccucc      840

ccccuaugca caacaaacac aaaagaaggc ucaaacaucu gcuuaacacg uacagaccga      900

gguugguacu gugauaacgc aggauccgua ucauuuuucc cacaagcaga aacaugcaaa      960

guacaaucaa accgcguuuu uugugacacc augaacagca gaacccuccc uucagaagua     1020

aaccuaugca acgucgauau auuuaaccca aaauacgauu gcaaaauaau gacaucaaaa     1080

accgaugucu caucuucagu aauaaccucu cuaggagcaa uagucucaug uuacggaaaa     1140

acaaaaugca cagcaaguaa uaaaaauaga ggaauaauaa aaacauucuc uaauggcugc     1200

gacuacguau ccaauaaagg cguugacaca guauccguag gcaacacacu cuacuauguu     1260

aacaaacaag aaggaaaaag uuuauacguu aaaggagaac caauuauaaa cuuuuacgac     1320

ccacucguau ucccaucuga ugaauuugac gcaucaaucu cacaaguaaa ugaaaaaauc     1380

aaucaguccc uugccuuuau aagaaaauca gaugaacuuu uacacaacgu uaacgccgga     1440

aaaucaacaa ccaauauaau gaucacaacc auaauaauag uuauaauugu aauuuuauua     1500

uccuuaauag ccgucggacu acuacuauac ugcaaagcaa gaucuacacc cguaacccua     1560

ucaaaagacc aacuaagugg aauaaauaac auugcauucu caaauuaa                  1608


<210>  3858
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut0

<400>  3858
auggaacucc uaauacuaaa ggcaaacgca aucacuacaa uucuaaccgc cgugacauuc       60

ugcuucgccu ccggacaaaa caucaccgaa gaauuuuacc aauccacaug cucggccguc      120

aguaaaggcu accucucggc ucuccgaacc ggcugguaca ccuccgucau caccaucgaa      180

cucuccaaca ucaaagaaaa caaaugcaac ggcaccgacg ccaaagucaa acuaaucaaa      240

caagaacucg acaaauacaa aaacgccguc acagaacucc aacuacuaau gcaaucaaca      300

cccgcuacag gaagcggcuc cgccaucgcc agcggcguag cugucugcaa aguccuccac      360

cucgaaggug aagucaacaa aaucaaauca gcccuacuca gcacaaacaa agccguugua      420

agccuaucca acggcgucuc cguacuaaca uucaaagucc uugaccucaa gaacuacauc      480

gacaaacaac uucucccaau ccuaaacaaa caaagcugcu caauuuccaa caucgaaaca      540

guaaucgaau uucaacaaaa aaacaaccga cuccucgaaa ucacccgcga auuuuccguu      600

aacgccggcg uuacaacccc cgucuccacc uacaugcuca ccaauuccga acuacuauca      660

cucauaaacg acaugccuau cacaaacgac caaaaaaaac uaaugucaaa caauguccaa      720

aucguccgcc agcaaagcua uuccaucaug ugcaucauca aagaggaagu ccucgccuac      780

guaguccaac ugccccucua cggcgucauu gauacccccu gcuggaaacu ccacaccucc      840

ccccucugca ccacaaacac caaagaaggu uccaacaucu gccuaacacg aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cccaagcaga aaccuguaaa      960

guccagucua accgcgucuu cugcgacaca augaacucaa gaacccuacc uuccgaagua     1020

aaccucugca acguagacau cuucaacccu aaauacgacu gcaaaaucau gacuucaaaa     1080

acagacguaa gcucuuccgu aaucacuucc cucggcgcca ucguauccug cuacgguaaa     1140

accaaaugca ccgccuccaa caaaaaccga gggaucauaa aaaccuucuc caacggcugc     1200

gacuacguau cuaacaaagg cgucgacacc gucuccgucg gcaacacccu cuauuacgua     1260

aacaaacaag agggcaaauc acuauacguc aaaggcgagc caaucauaaa cuucuaugac     1320

ccacucgucu ucccuucaga cgaauuugau gccagcauca gccaagucaa cgaaaaaauc     1380

aaccaaucac ucgccuucau ccgcaaaagc gacgaacucc uucacaacgu caacgcaggc     1440

aaaucaacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu uauccuacuc     1500

agccucaucg caguuggucu ucuccuuuac ugcaaagccc gcuccacccc cgucacccuc     1560

aguaaagacc aacucagcgg aaucaacaac auagcauucu ccaacuaa                  1608


<210>  3859
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3859
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3860
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3860
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3861
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3861
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3862
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3862
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcuuucucaa     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3863
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3863
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3864
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3864
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3865
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3865
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uacuaaaagc caaugcaaua acaaccauac      120

uaaccgccgu aacauuuugu uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau      180

caacaugcuc agcaguauca aaaggauacu uauccgcucu aagaacagga ugguacacaa      240

guguaauuac aauagagcuc ucaaacauaa aagaaaacaa augcaaugga acugacgcaa      300

aaguuaaacu uauaaaacaa gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac      360

uccuaaugca auccacaccu gcuaccgguu ccggaucagc cauagcaucu ggaguagccg      420

uaugcaaagu ccuccaccua gaaggagaag uaaauaaaau caaaucagca cuauuaucua      480

ccaauaaagc aguugucuca cuauccaaug gcguaucagu acuaacauuc aaaguauuag      540

accuuaaaaa cuacauagac aaacaacuau uaccaauucu gaacaaacaa uccuguucaa      600

uaucaaacau cgaaacggua auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa      660

caagagaauu uucaguaaau gcaggaguua caacacccgu cuccaccuac augcucacaa      720

auucagaauu auuaucacuu auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaaua guccgacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu agccuacguu guccaacuac ccuuauaugg aguaauagau accccaugcu      900

ggaaacuuca uaccuccccc cuaugcacaa caaacacaaa agaaggcuca aacaucugcu      960

uaacacguac agaccgaggu ugguacugug auaacgcagg auccguauca uuuuucccac     1020

aagcagaaac augcaaagua caaucaaacc gcguuuuuug ugacaccaug aacagcagaa     1080

cccucccuuc agaaguaaac cuaugcaacg ucgauauauu uaacccaaaa uacgauugca     1140

aaauaaugac aucaaaaacc gaugucucau cuucaguaau aaccucucua ggagcaauag     1200

ucucauguua cggaaaaaca aaaugcacag caaguaauaa aaauagagga auaauaaaaa     1260

cauucucuaa uggcugcgac uacguaucca auaaaggcgu ugacacagua uccguaggca     1320

acacacucua cuauguuaac aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa     1380

uuauaaacuu uuacgaccca cucguauucc caucugauga auuugacgca ucaaucucac     1440

aaguaaauga aaaaaucaau cagucccuug ccuuuauaag aaaaucagau gaacuuuuac     1500

acaacguuaa cgccggaaaa ucaacaacca auauaaugau cacaaccaua auaauaguua     1560

uaauuguaau uuuauuaucc uuaauagccg ucggacuacu acuauacugc aaagcaagau     1620

cuacacccgu aacccuauca aaagaccaac uaaguggaau aaauaacauu gcauucucaa     1680

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3866
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3866
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc      120

uaaccgccgu gacauucugc uucgccuccg gacaaaacau caccgaagaa uuuuaccaau      180

ccacaugcuc ggccgucagu aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu      240

ccgucaucac caucgaacuc uccaacauca aagaaaacaa augcaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacucgaca aauacaaaaa cgccgucaca gaacuccaac      360

uacuaaugca aucaacaccc gcuacaggaa gcggcuccgc caucgccagc ggcguagcug      420

ucugcaaagu ccuccaccuc gaaggugaag ucaacaaaau caaaucagcc cuacucagca      480

caaacaaagc cguuguaagc cuauccaacg gcgucuccgu acuaacauuc aaaguccuug      540

accucaagaa cuacaucgac aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa      600

uuuccaacau cgaaacagua aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca      660

cccgcgaauu uuccguuaac gccggcguua caacccccgu cuccaccuac augcucacca      720

auuccgaacu acuaucacuc auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaauc guccgccagc aaagcuauuc caucaugugc aucaucaaag      840

aggaaguccu cgccuacgua guccaacugc cccucuacgg cgucauugau acccccugcu      900

ggaaacucca caccuccccc cucugcacca caaacaccaa agaagguucc aacaucugcc      960

uaacacgaac cgacagaggc ugguacugcg acaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cuguaaaguc cagucuaacc gcgucuucug cgacacaaug aacucaagaa     1080

cccuaccuuc cgaaguaaac cucugcaacg uagacaucuu caacccuaaa uacgacugca     1140

aaaucaugac uucaaaaaca gacguaagcu cuuccguaau cacuucccuc ggcgccaucg     1200

uauccugcua cgguaaaacc aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa     1260

ccuucuccaa cggcugcgac uacguaucua acaaaggcgu cgacaccguc uccgucggca     1320

acacccucua uuacguaaac aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa     1380

ucauaaacuu cuaugaccca cucgucuucc cuucagacga auuugaugcc agcaucagcc     1440

aagucaacga aaaaaucaac caaucacucg ccuucauccg caaaagcgac gaacuccuuc     1500

acaacgucaa cgcaggcaaa ucaaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucguuau ccuacucagc cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu     1620

ccacccccgu cacccucagu aaagaccaac ucagcggaau caacaacaua gcauucucca     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  3867
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3867
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3868
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3868
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3869
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3869
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3870
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3870
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cuuucucaaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3871
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3871
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3872
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3872
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3873
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3873
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau acuaaaagcc      120

aaugcaauaa caaccauacu aaccgccgua acauuuuguu ucgcaucagg ucaaaacaua      180

accgaagaau uuuaucaauc aacaugcuca gcaguaucaa aaggauacuu auccgcucua      240

agaacaggau gguacacaag uguaauuaca auagagcucu caaacauaaa agaaaacaaa      300

ugcaauggaa cugacgcaaa aguuaaacuu auaaaacaag aacuagauaa auauaaaaau      360

gcaguaaccg aauuacaacu ccuaaugcaa uccacaccug cuaccgguuc cggaucagcc      420

auagcaucug gaguagccgu augcaaaguc cuccaccuag aaggagaagu aaauaaaauc      480

aaaucagcac uauuaucuac caauaaagca guugucucac uauccaaugg cguaucagua      540

cuaacauuca aaguauuaga ccuuaaaaac uacauagaca aacaacuauu accaauucug      600

aacaaacaau ccuguucaau aucaaacauc gaaacgguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaauaac aagagaauuu ucaguaaaug caggaguuac aacacccguc      720

uccaccuaca ugcucacaaa uucagaauua uuaucacuua uaaacgacau gccaauaacu      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaauag uccgacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccua gccuacguug uccaacuacc cuuauaugga      900

guaauagaua ccccaugcug gaaacuucau accucccccc uaugcacaac aaacacaaaa      960

gaaggcucaa acaucugcuu aacacguaca gaccgagguu gguacuguga uaacgcagga     1020

uccguaucau uuuucccaca agcagaaaca ugcaaaguac aaucaaaccg cguuuuuugu     1080

gacaccauga acagcagaac ccucccuuca gaaguaaacc uaugcaacgu cgauauauuu     1140

aacccaaaau acgauugcaa aauaaugaca ucaaaaaccg augucucauc uucaguaaua     1200

accucucuag gagcaauagu cucauguuac ggaaaaacaa aaugcacagc aaguaauaaa     1260

aauagaggaa uaauaaaaac auucucuaau ggcugcgacu acguauccaa uaaaggcguu     1320

gacacaguau ccguaggcaa cacacucuac uauguuaaca aacaagaagg aaaaaguuua     1380

uacguuaaag gagaaccaau uauaaacuuu uacgacccac ucguauuccc aucugaugaa     1440

uuugacgcau caaucucaca aguaaaugaa aaaaucaauc agucccuugc cuuuauaaga     1500

aaaucagaug aacuuuuaca caacguuaac gccggaaaau caacaaccaa uauaaugauc     1560

acaaccauaa uaauaguuau aauuguaauu uuauuauccu uaauagccgu cggacuacua     1620

cuauacugca aagcaagauc uacacccgua acccuaucaa aagaccaacu aaguggaaua     1680

aauaacauug cauucucaaa uuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3874
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3874
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuaaaggca      120

aacgcaauca cuacaauucu aaccgccgug acauucugcu ucgccuccgg acaaaacauc      180

accgaagaau uuuaccaauc cacaugcucg gccgucagua aaggcuaccu cucggcucuc      240

cgaaccggcu gguacaccuc cgucaucacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgccaa agucaaacua aucaaacaag aacucgacaa auacaaaaac      360

gccgucacag aacuccaacu acuaaugcaa ucaacacccg cuacaggaag cggcuccgcc      420

aucgccagcg gcguagcugu cugcaaaguc cuccaccucg aaggugaagu caacaaaauc      480

aaaucagccc uacucagcac aaacaaagcc guuguaagcc uauccaacgg cgucuccgua      540

cuaacauuca aaguccuuga ccucaagaac uacaucgaca aacaacuucu cccaauccua      600

aacaaacaaa gcugcucaau uuccaacauc gaaacaguaa ucgaauuuca acaaaaaaac      660

aaccgacucc ucgaaaucac ccgcgaauuu uccguuaacg ccggcguuac aacccccguc      720

uccaccuaca ugcucaccaa uuccgaacua cuaucacuca uaaacgacau gccuaucaca      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaaucg uccgccagca aagcuauucc      840

aucaugugca ucaucaaaga ggaaguccuc gccuacguag uccaacugcc ccucuacggc      900

gucauugaua cccccugcug gaaacuccac accucccccc ucugcaccac aaacaccaaa      960

gaagguucca acaucugccu aacacgaacc gacagaggcu gguacugcga caacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc uguaaagucc agucuaaccg cgucuucugc     1080

gacacaauga acucaagaac ccuaccuucc gaaguaaacc ucugcaacgu agacaucuuc     1140

aacccuaaau acgacugcaa aaucaugacu ucaaaaacag acguaagcuc uuccguaauc     1200

acuucccucg gcgccaucgu auccugcuac gguaaaacca aaugcaccgc cuccaacaaa     1260

aaccgaggga ucauaaaaac cuucuccaac ggcugcgacu acguaucuaa caaaggcguc     1320

gacaccgucu ccgucggcaa cacccucuau uacguaaaca aacaagaggg caaaucacua     1380

uacgucaaag gcgagccaau cauaaacuuc uaugacccac ucgucuuccc uucagacgaa     1440

uuugaugcca gcaucagcca agucaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaaagcgacg aacuccuuca caacgucaac gcaggcaaau caaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucguuauc cuacucagcc ucaucgcagu uggucuucuc     1620

cuuuacugca aagcccgcuc cacccccguc acccucagua aagaccaacu cagcggaauc     1680

aacaacauag cauucuccaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  3875
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3875
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3876
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3876
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3877
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3877
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3878
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3878
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgcu uucucaaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3879
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3879
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3880
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3880
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3881
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3881
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaauac uaaaagccaa ugcaauaaca accauacuaa ccgccguaac auuuuguuuc      240

gcaucagguc aaaacauaac cgaagaauuu uaucaaucaa caugcucagc aguaucaaaa      300

ggauacuuau ccgcucuaag aacaggaugg uacacaagug uaauuacaau agagcucuca      360

aacauaaaag aaaacaaaug caauggaacu gacgcaaaag uuaaacuuau aaaacaagaa      420

cuagauaaau auaaaaaugc aguaaccgaa uuacaacucc uaaugcaauc cacaccugcu      480

accgguuccg gaucagccau agcaucugga guagccguau gcaaaguccu ccaccuagaa      540

ggagaaguaa auaaaaucaa aucagcacua uuaucuacca auaaagcagu ugucucacua      600

uccaauggcg uaucaguacu aacauucaaa guauuagacc uuaaaaacua cauagacaaa      660

caacuauuac caauucugaa caaacaaucc uguucaauau caaacaucga aacgguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaauaacaa gagaauuuuc aguaaaugca      780

ggaguuacaa cacccgucuc caccuacaug cucacaaauu cagaauuauu aucacuuaua      840

aacgacaugc caauaacuaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaauaguc      900

cgacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccuagc cuacguuguc      960

caacuacccu uauauggagu aauagauacc ccaugcugga aacuucauac cuccccccua     1020

ugcacaacaa acacaaaaga aggcucaaac aucugcuuaa cacguacaga ccgagguugg     1080

uacugugaua acgcaggauc cguaucauuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaaccgcg uuuuuuguga caccaugaac agcagaaccc ucccuucaga aguaaaccua     1200

ugcaacgucg auauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaaccgau     1260

gucucaucuu caguaauaac cucucuagga gcaauagucu cauguuacgg aaaaacaaaa     1320

ugcacagcaa guaauaaaaa uagaggaaua auaaaaacau ucucuaaugg cugcgacuac     1380

guauccaaua aaggcguuga cacaguaucc guaggcaaca cacucuacua uguuaacaaa     1440

caagaaggaa aaaguuuaua cguuaaagga gaaccaauua uaaacuuuua cgacccacuc     1500

guauucccau cugaugaauu ugacgcauca aucucacaag uaaaugaaaa aaucaaucag     1560

ucccuugccu uuauaagaaa aucagaugaa cuuuuacaca acguuaacgc cggaaaauca     1620

acaaccaaua uaaugaucac aaccauaaua auaguuauaa uuguaauuuu auuauccuua     1680

auagccgucg gacuacuacu auacugcaaa gcaagaucua cacccguaac ccuaucaaaa     1740

gaccaacuaa guggaauaaa uaacauugca uucucaaauu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3882
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3882
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uaaaggcaaa cgcaaucacu acaauucuaa ccgccgugac auucugcuuc      240

gccuccggac aaaacaucac cgaagaauuu uaccaaucca caugcucggc cgucaguaaa      300

ggcuaccucu cggcucuccg aaccggcugg uacaccuccg ucaucaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cucgacaaau acaaaaacgc cgucacagaa cuccaacuac uaaugcaauc aacacccgcu      480

acaggaagcg gcuccgccau cgccagcggc guagcugucu gcaaaguccu ccaccucgaa      540

ggugaaguca acaaaaucaa aucagcccua cucagcacaa acaaagccgu uguaagccua      600

uccaacggcg ucuccguacu aacauucaaa guccuugacc ucaagaacua caucgacaaa      660

caacuucucc caauccuaaa caaacaaagc ugcucaauuu ccaacaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ccgacuccuc gaaaucaccc gcgaauuuuc cguuaacgcc      780

ggcguuacaa cccccgucuc caccuacaug cucaccaauu ccgaacuacu aucacucaua      840

aacgacaugc cuaucacaaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaaucguc      900

cgccagcaaa gcuauuccau caugugcauc aucaaagagg aaguccucgc cuacguaguc      960

caacugcccc ucuacggcgu cauugauacc cccugcugga aacuccacac cuccccccuc     1020

ugcaccacaa acaccaaaga agguuccaac aucugccuaa cacgaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccaag cagaaaccug uaaaguccag     1140

ucuaaccgcg ucuucugcga cacaaugaac ucaagaaccc uaccuuccga aguaaaccuc     1200

ugcaacguag acaucuucaa cccuaaauac gacugcaaaa ucaugacuuc aaaaacagac     1260

guaagcucuu ccguaaucac uucccucggc gccaucguau ccugcuacgg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgagggauc auaaaaaccu ucuccaacgg cugcgacuac     1380

guaucuaaca aaggcgucga caccgucucc gucggcaaca cccucuauua cguaaacaaa     1440

caagagggca aaucacuaua cgucaaaggc gagccaauca uaaacuucua ugacccacuc     1500

gucuucccuu cagacgaauu ugaugccagc aucagccaag ucaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa aagcgacgaa cuccuucaca acgucaacgc aggcaaauca     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucguuauccu acucagccuc     1680

aucgcaguug gucuucuccu uuacugcaaa gcccgcucca cccccgucac ccucaguaaa     1740

gaccaacuca gcggaaucaa caacauagca uucuccaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  3883
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3883
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3884
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3884
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3885
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3885
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3886
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3886
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcuu ucucaaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3887
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3887
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3888
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3888
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3889
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3889
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauacu aaaagccaau gcaauaacaa ccauacuaac cgccguaaca      180

uuuuguuucg caucagguca aaacauaacc gaagaauuuu aucaaucaac augcucagca      240

guaucaaaag gauacuuauc cgcucuaaga acaggauggu acacaagugu aauuacaaua      300

gagcucucaa acauaaaaga aaacaaaugc aauggaacug acgcaaaagu uaaacuuaua      360

aaacaagaac uagauaaaua uaaaaaugca guaaccgaau uacaacuccu aaugcaaucc      420

acaccugcua ccgguuccgg aucagccaua gcaucuggag uagccguaug caaaguccuc      480

caccuagaag gagaaguaaa uaaaaucaaa ucagcacuau uaucuaccaa uaaagcaguu      540

gucucacuau ccaauggcgu aucaguacua acauucaaag uauuagaccu uaaaaacuac      600

auagacaaac aacuauuacc aauucugaac aaacaauccu guucaauauc aaacaucgaa      660

acgguaauag aauuucaaca aaaaaauaac agauuacuug aaauaacaag agaauuuuca      720

guaaaugcag gaguuacaac acccgucucc accuacaugc ucacaaauuc agaauuauua      780

ucacuuauaa acgacaugcc aauaacuaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaauagucc gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccuagcc      900

uacguugucc aacuacccuu auauggagua auagauaccc caugcuggaa acuucauacc      960

uccccccuau gcacaacaaa cacaaaagaa ggcucaaaca ucugcuuaac acguacagac     1020

cgagguuggu acugugauaa cgcaggaucc guaucauuuu ucccacaagc agaaacaugc     1080

aaaguacaau caaaccgcgu uuuuugugac accaugaaca gcagaacccu cccuucagaa     1140

guaaaccuau gcaacgucga uauauuuaac ccaaaauacg auugcaaaau aaugacauca     1200

aaaaccgaug ucucaucuuc aguaauaacc ucucuaggag caauagucuc auguuacgga     1260

aaaacaaaau gcacagcaag uaauaaaaau agaggaauaa uaaaaacauu cucuaauggc     1320

ugcgacuacg uauccaauaa aggcguugac acaguauccg uaggcaacac acucuacuau     1380

guuaacaaac aagaaggaaa aaguuuauac guuaaaggag aaccaauuau aaacuuuuac     1440

gacccacucg uauucccauc ugaugaauuu gacgcaucaa ucucacaagu aaaugaaaaa     1500

aucaaucagu cccuugccuu uauaagaaaa ucagaugaac uuuuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaauau aaugaucaca accauaauaa uaguuauaau uguaauuuua     1620

uuauccuuaa uagccgucgg acuacuacua uacugcaaag caagaucuac acccguaacc     1680

cuaucaaaag accaacuaag uggaauaaau aacauugcau ucucaaauua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3890
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3890
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu aaaggcaaac gcaaucacua caauucuaac cgccgugaca      180

uucugcuucg ccuccggaca aaacaucacc gaagaauuuu accaauccac augcucggcc      240

gucaguaaag gcuaccucuc ggcucuccga accggcuggu acaccuccgu caucaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagaac uccaacuacu aaugcaauca      420

acacccgcua caggaagcgg cuccgccauc gccagcggcg uagcugucug caaaguccuc      480

caccucgaag gugaagucaa caaaaucaaa ucagcccuac ucagcacaaa caaagccguu      540

guaagccuau ccaacggcgu cuccguacua acauucaaag uccuugaccu caagaacuac      600

aucgacaaac aacuucuccc aauccuaaac aaacaaagcu gcucaauuuc caacaucgaa      660

acaguaaucg aauuucaaca aaaaaacaac cgacuccucg aaaucacccg cgaauuuucc      720

guuaacgccg gcguuacaac ccccgucucc accuacaugc ucaccaauuc cgaacuacua      780

ucacucauaa acgacaugcc uaucacaaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaaucgucc gccagcaaag cuauuccauc augugcauca ucaaagagga aguccucgcc      900

uacguagucc aacugccccu cuacggcguc auugauaccc ccugcuggaa acuccacacc      960

uccccccucu gcaccacaaa caccaaagaa gguuccaaca ucugccuaac acgaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gucuccuucu ucccccaagc agaaaccugu     1080

aaaguccagu cuaaccgcgu cuucugcgac acaaugaacu caagaacccu accuuccgaa     1140

guaaaccucu gcaacguaga caucuucaac ccuaaauacg acugcaaaau caugacuuca     1200

aaaacagacg uaagcucuuc cguaaucacu ucccucggcg ccaucguauc cugcuacggu     1260

aaaaccaaau gcaccgccuc caacaaaaac cgagggauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg uaucuaacaa aggcgucgac accgucuccg ucggcaacac ccucuauuac     1380

guaaacaaac aagagggcaa aucacuauac gucaaaggcg agccaaucau aaacuucuau     1440

gacccacucg ucuucccuuc agacgaauuu gaugccagca ucagccaagu caacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa agcgacgaac uccuucacaa cgucaacgca     1560

ggcaaaucaa ccaccaacau caugaucacc accaucauca ucgucaucau cguuauccua     1620

cucagccuca ucgcaguugg ucuucuccuu uacugcaaag cccgcuccac ccccgucacc     1680

cucaguaaag accaacucag cggaaucaac aacauagcau ucuccaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  3891
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3891
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3892
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3892
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3893
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3893
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3894
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3894
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcuuucuc aaacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3895
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3895
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3896
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3896
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3897
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3897
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauacuaaaa gccaaugcaa uaacaaccau acuaaccgcc      120

guaacauuuu guuucgcauc aggucaaaac auaaccgaag aauuuuauca aucaacaugc      180

ucagcaguau caaaaggaua cuuauccgcu cuaagaacag gaugguacac aaguguaauu      240

acaauagagc ucucaaacau aaaagaaaac aaaugcaaug gaacugacgc aaaaguuaaa      300

cuuauaaaac aagaacuaga uaaauauaaa aaugcaguaa ccgaauuaca acuccuaaug      360

caauccacac cugcuaccgg uuccggauca gccauagcau cuggaguagc cguaugcaaa      420

guccuccacc uagaaggaga aguaaauaaa aucaaaucag cacuauuauc uaccaauaaa      480

gcaguugucu cacuauccaa uggcguauca guacuaacau ucaaaguauu agaccuuaaa      540

aacuacauag acaaacaacu auuaccaauu cugaacaaac aauccuguuc aauaucaaac      600

aucgaaacgg uaauagaauu ucaacaaaaa aauaacagau uacuugaaau aacaagagaa      660

uuuucaguaa augcaggagu uacaacaccc gucuccaccu acaugcucac aaauucagaa      720

uuauuaucac uuauaaacga caugccaaua acuaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa uaguccgaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cuagccuacg uuguccaacu acccuuauau ggaguaauag auaccccaug cuggaaacuu      900

cauaccuccc cccuaugcac aacaaacaca aaagaaggcu caaacaucug cuuaacacgu      960

acagaccgag guugguacug ugauaacgca ggauccguau cauuuuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa ccgcguuuuu ugugacacca ugaacagcag aacccucccu     1080

ucagaaguaa accuaugcaa cgucgauaua uuuaacccaa aauacgauug caaaauaaug     1140

acaucaaaaa ccgaugucuc aucuucagua auaaccucuc uaggagcaau agucucaugu     1200

uacggaaaaa caaaaugcac agcaaguaau aaaaauagag gaauaauaaa aacauucucu     1260

aauggcugcg acuacguauc caauaaaggc guugacacag uauccguagg caacacacuc     1320

uacuauguua acaaacaaga aggaaaaagu uuauacguua aaggagaacc aauuauaaac     1380

uuuuacgacc cacucguauu cccaucugau gaauuugacg caucaaucuc acaaguaaau     1440

gaaaaaauca aucagucccu ugccuuuaua agaaaaucag augaacuuuu acacaacguu     1500

aacgccggaa aaucaacaac caauauaaug aucacaacca uaauaauagu uauaauugua     1560

auuuuauuau ccuuaauagc cgucggacua cuacuauacu gcaaagcaag aucuacaccc     1620

guaacccuau caaaagacca acuaagugga auaaauaaca uugcauucuc aaauuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3898
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3898
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuaaag gcaaacgcaa ucacuacaau ucuaaccgcc      120

gugacauucu gcuucgccuc cggacaaaac aucaccgaag aauuuuacca auccacaugc      180

ucggccguca guaaaggcua ccucucggcu cuccgaaccg gcugguacac cuccgucauc      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacucga caaauacaaa aacgccguca cagaacucca acuacuaaug      360

caaucaacac ccgcuacagg aagcggcucc gccaucgcca gcggcguagc ugucugcaaa      420

guccuccacc ucgaagguga agucaacaaa aucaaaucag cccuacucag cacaaacaaa      480

gccguuguaa gccuauccaa cggcgucucc guacuaacau ucaaaguccu ugaccucaag      540

aacuacaucg acaaacaacu ucucccaauc cuaaacaaac aaagcugcuc aauuuccaac      600

aucgaaacag uaaucgaauu ucaacaaaaa aacaaccgac uccucgaaau cacccgcgaa      660

uuuuccguua acgccggcgu uacaaccccc gucuccaccu acaugcucac caauuccgaa      720

cuacuaucac ucauaaacga caugccuauc acaaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa ucguccgcca gcaaagcuau uccaucaugu gcaucaucaa agaggaaguc      840

cucgccuacg uaguccaacu gccccucuac ggcgucauug auacccccug cuggaaacuc      900

cacaccuccc cccucugcac cacaaacacc aaagaagguu ccaacaucug ccuaacacga      960

accgacagag gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accuguaaag uccagucuaa ccgcgucuuc ugcgacacaa ugaacucaag aacccuaccu     1080

uccgaaguaa accucugcaa cguagacauc uucaacccua aauacgacug caaaaucaug     1140

acuucaaaaa cagacguaag cucuuccgua aucacuuccc ucggcgccau cguauccugc     1200

uacgguaaaa ccaaaugcac cgccuccaac aaaaaccgag ggaucauaaa aaccuucucc     1260

aacggcugcg acuacguauc uaacaaaggc gucgacaccg ucuccgucgg caacacccuc     1320

uauuacguaa acaaacaaga gggcaaauca cuauacguca aaggcgagcc aaucauaaac     1380

uucuaugacc cacucgucuu cccuucagac gaauuugaug ccagcaucag ccaagucaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaaagcg acgaacuccu ucacaacguc     1500

aacgcaggca aaucaaccac caacaucaug aucaccacca ucaucaucgu caucaucguu     1560

auccuacuca gccucaucgc aguuggucuu cuccuuuacu gcaaagcccg cuccaccccc     1620

gucacccuca guaaagacca acucagcgga aucaacaaca uagcauucuc caacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  3899
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3899
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1800

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3900
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3900
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      600

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      660

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1140

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1260

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1380

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1440

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1500

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1800

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3901
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3901
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1500

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1800

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3902
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3902
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      600

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      660

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      720

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      840

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      900

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      960

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua     1020

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca     1080

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc     1140

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1200

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1260

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1320

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1380

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1440

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1500

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1560

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1620

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1680

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1740

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1800

aaggaccagc ucuccggcau aaacaauauc gcuuucucaa acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3903
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3903
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1800

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3904
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3904
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      600

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      660

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      720

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      840

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      900

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      960

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug     1020

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu     1080

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga     1140

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1200

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1260

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1320

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1380

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1440

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1500

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1560

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1620

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1740

cugaucgccg ugggccuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1800

aaggaccagc ucucugggau uaacaauauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3905
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3905
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuaa uacuaaaagc caaugcaaua acaaccauac uaaccgccgu aacauuuugu      300

uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau caacaugcuc agcaguauca      360

aaaggauacu uauccgcucu aagaacagga ugguacacaa guguaauuac aauagagcuc      420

ucaaacauaa aagaaaacaa augcaaugga acugacgcaa aaguuaaacu uauaaaacaa      480

gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac uccuaaugca auccacaccu      540

gcuaccgguu ccggaucagc cauagcaucu ggaguagccg uaugcaaagu ccuccaccua      600

gaaggagaag uaaauaaaau caaaucagca cuauuaucua ccaauaaagc aguugucuca      660

cuauccaaug gcguaucagu acuaacauuc aaaguauuag accuuaaaaa cuacauagac      720

aaacaacuau uaccaauucu gaacaaacaa uccuguucaa uaucaaacau cgaaacggua      780

auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa caagagaauu uucaguaaau      840

gcaggaguua caacacccgu cuccaccuac augcucacaa auucagaauu auuaucacuu      900

auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa ugucaaacaa uguccaaaua      960

guccgacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu agccuacguu     1020

guccaacuac ccuuauaugg aguaauagau accccaugcu ggaaacuuca uaccuccccc     1080

cuaugcacaa caaacacaaa agaaggcuca aacaucugcu uaacacguac agaccgaggu     1140

ugguacugug auaacgcagg auccguauca uuuuucccac aagcagaaac augcaaagua     1200

caaucaaacc gcguuuuuug ugacaccaug aacagcagaa cccucccuuc agaaguaaac     1260

cuaugcaacg ucgauauauu uaacccaaaa uacgauugca aaauaaugac aucaaaaacc     1320

gaugucucau cuucaguaau aaccucucua ggagcaauag ucucauguua cggaaaaaca     1380

aaaugcacag caaguaauaa aaauagagga auaauaaaaa cauucucuaa uggcugcgac     1440

uacguaucca auaaaggcgu ugacacagua uccguaggca acacacucua cuauguuaac     1500

aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa uuauaaacuu uuacgaccca     1560

cucguauucc caucugauga auuugacgca ucaaucucac aaguaaauga aaaaaucaau     1620

cagucccuug ccuuuauaag aaaaucagau gaacuuuuac acaacguuaa cgccggaaaa     1680

ucaacaacca auauaaugau cacaaccaua auaauaguua uaauuguaau uuuauuaucc     1740

uuaauagccg ucggacuacu acuauacugc aaagcaagau cuacacccgu aacccuauca     1800

aaagaccaac uaaguggaau aaauaacauu gcauucucaa auuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3906
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3906
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc uaaccgccgu gacauucugc      300

uucgccuccg gacaaaacau caccgaagaa uuuuaccaau ccacaugcuc ggccgucagu      360

aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu ccgucaucac caucgaacuc      420

uccaacauca aagaaaacaa augcaacggc accgacgcca aagucaaacu aaucaaacaa      480

gaacucgaca aauacaaaaa cgccgucaca gaacuccaac uacuaaugca aucaacaccc      540

gcuacaggaa gcggcuccgc caucgccagc ggcguagcug ucugcaaagu ccuccaccuc      600

gaaggugaag ucaacaaaau caaaucagcc cuacucagca caaacaaagc cguuguaagc      660

cuauccaacg gcgucuccgu acuaacauuc aaaguccuug accucaagaa cuacaucgac      720

aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa uuuccaacau cgaaacagua      780

aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca cccgcgaauu uuccguuaac      840

gccggcguua caacccccgu cuccaccuac augcucacca auuccgaacu acuaucacuc      900

auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa ugucaaacaa uguccaaauc      960

guccgccagc aaagcuauuc caucaugugc aucaucaaag aggaaguccu cgccuacgua     1020

guccaacugc cccucuacgg cgucauugau acccccugcu ggaaacucca caccuccccc     1080

cucugcacca caaacaccaa agaagguucc aacaucugcc uaacacgaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuuccccc aagcagaaac cuguaaaguc     1200

cagucuaacc gcgucuucug cgacacaaug aacucaagaa cccuaccuuc cgaaguaaac     1260

cucugcaacg uagacaucuu caacccuaaa uacgacugca aaaucaugac uucaaaaaca     1320

gacguaagcu cuuccguaau cacuucccuc ggcgccaucg uauccugcua cgguaaaacc     1380

aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa ccuucuccaa cggcugcgac     1440

uacguaucua acaaaggcgu cgacaccguc uccgucggca acacccucua uuacguaaac     1500

aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa ucauaaacuu cuaugaccca     1560

cucgucuucc cuucagacga auuugaugcc agcaucagcc aagucaacga aaaaaucaac     1620

caaucacucg ccuucauccg caaaagcgac gaacuccuuc acaacgucaa cgcaggcaaa     1680

ucaaccacca acaucaugau caccaccauc aucaucguca ucaucguuau ccuacucagc     1740

cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu ccacccccgu cacccucagu     1800

aaagaccaac ucagcggaau caacaacaua gcauucucca acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  3907
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3907
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3908
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3908
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1620

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3909
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3909
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3910
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3910
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca      900

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc      960

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1020

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1200

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1320

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1620

aaggaccagc ucuccggcau aaacaauauc gcuuucucaa acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3911
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3911
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3912
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3912
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu      900

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga      960

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1020

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1320

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1620

aaggaccagc ucucugggau uaacaauauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3913
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3913
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuaa uacuaaaagc caaugcaaua acaaccauac uaaccgccgu aacauuuugu      120

uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau caacaugcuc agcaguauca      180

aaaggauacu uauccgcucu aagaacagga ugguacacaa guguaauuac aauagagcuc      240

ucaaacauaa aagaaaacaa augcaaugga acugacgcaa aaguuaaacu uauaaaacaa      300

gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac uccuaaugca auccacaccu      360

gcuaccgguu ccggaucagc cauagcaucu ggaguagccg uaugcaaagu ccuccaccua      420

gaaggagaag uaaauaaaau caaaucagca cuauuaucua ccaauaaagc aguugucuca      480

cuauccaaug gcguaucagu acuaacauuc aaaguauuag accuuaaaaa cuacauagac      540

aaacaacuau uaccaauucu gaacaaacaa uccuguucaa uaucaaacau cgaaacggua      600

auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa caagagaauu uucaguaaau      660

gcaggaguua caacacccgu cuccaccuac augcucacaa auucagaauu auuaucacuu      720

auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa ugucaaacaa uguccaaaua      780

guccgacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu agccuacguu      840

guccaacuac ccuuauaugg aguaauagau accccaugcu ggaaacuuca uaccuccccc      900

cuaugcacaa caaacacaaa agaaggcuca aacaucugcu uaacacguac agaccgaggu      960

ugguacugug auaacgcagg auccguauca uuuuucccac aagcagaaac augcaaagua     1020

caaucaaacc gcguuuuuug ugacaccaug aacagcagaa cccucccuuc agaaguaaac     1080

cuaugcaacg ucgauauauu uaacccaaaa uacgauugca aaauaaugac aucaaaaacc     1140

gaugucucau cuucaguaau aaccucucua ggagcaauag ucucauguua cggaaaaaca     1200

aaaugcacag caaguaauaa aaauagagga auaauaaaaa cauucucuaa uggcugcgac     1260

uacguaucca auaaaggcgu ugacacagua uccguaggca acacacucua cuauguuaac     1320

aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa uuauaaacuu uuacgaccca     1380

cucguauucc caucugauga auuugacgca ucaaucucac aaguaaauga aaaaaucaau     1440

cagucccuug ccuuuauaag aaaaucagau gaacuuuuac acaacguuaa cgccggaaaa     1500

ucaacaacca auauaaugau cacaaccaua auaauaguua uaauuguaau uuuauuaucc     1560

uuaauagccg ucggacuacu acuauacugc aaagcaagau cuacacccgu aacccuauca     1620

aaagaccaac uaaguggaau aaauaacauu gcauucucaa auuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3914
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3914
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc uaaccgccgu gacauucugc      120

uucgccuccg gacaaaacau caccgaagaa uuuuaccaau ccacaugcuc ggccgucagu      180

aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu ccgucaucac caucgaacuc      240

uccaacauca aagaaaacaa augcaacggc accgacgcca aagucaaacu aaucaaacaa      300

gaacucgaca aauacaaaaa cgccgucaca gaacuccaac uacuaaugca aucaacaccc      360

gcuacaggaa gcggcuccgc caucgccagc ggcguagcug ucugcaaagu ccuccaccuc      420

gaaggugaag ucaacaaaau caaaucagcc cuacucagca caaacaaagc cguuguaagc      480

cuauccaacg gcgucuccgu acuaacauuc aaaguccuug accucaagaa cuacaucgac      540

aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa uuuccaacau cgaaacagua      600

aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca cccgcgaauu uuccguuaac      660

gccggcguua caacccccgu cuccaccuac augcucacca auuccgaacu acuaucacuc      720

auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa ugucaaacaa uguccaaauc      780

guccgccagc aaagcuauuc caucaugugc aucaucaaag aggaaguccu cgccuacgua      840

guccaacugc cccucuacgg cgucauugau acccccugcu ggaaacucca caccuccccc      900

cucugcacca caaacaccaa agaagguucc aacaucugcc uaacacgaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgucucc uucuuccccc aagcagaaac cuguaaaguc     1020

cagucuaacc gcgucuucug cgacacaaug aacucaagaa cccuaccuuc cgaaguaaac     1080

cucugcaacg uagacaucuu caacccuaaa uacgacugca aaaucaugac uucaaaaaca     1140

gacguaagcu cuuccguaau cacuucccuc ggcgccaucg uauccugcua cgguaaaacc     1200

aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa ccuucuccaa cggcugcgac     1260

uacguaucua acaaaggcgu cgacaccguc uccgucggca acacccucua uuacguaaac     1320

aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa ucauaaacuu cuaugaccca     1380

cucgucuucc cuucagacga auuugaugcc agcaucagcc aagucaacga aaaaaucaac     1440

caaucacucg ccuucauccg caaaagcgac gaacuccuuc acaacgucaa cgcaggcaaa     1500

ucaaccacca acaucaugau caccaccauc aucaucguca ucaucguuau ccuacucagc     1560

cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu ccacccccgu cacccucagu     1620

aaagaccaac ucagcggaau caacaacaua gcauucucca acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  3915
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3915
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3916
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3916
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3917
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3917
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3918
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3918
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcuuucucaa     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3919
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3919
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3920
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3920
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3921
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3921
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uacuaaaagc caaugcaaua acaaccauac      120

uaaccgccgu aacauuuugu uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau      180

caacaugcuc agcaguauca aaaggauacu uauccgcucu aagaacagga ugguacacaa      240

guguaauuac aauagagcuc ucaaacauaa aagaaaacaa augcaaugga acugacgcaa      300

aaguuaaacu uauaaaacaa gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac      360

uccuaaugca auccacaccu gcuaccgguu ccggaucagc cauagcaucu ggaguagccg      420

uaugcaaagu ccuccaccua gaaggagaag uaaauaaaau caaaucagca cuauuaucua      480

ccaauaaagc aguugucuca cuauccaaug gcguaucagu acuaacauuc aaaguauuag      540

accuuaaaaa cuacauagac aaacaacuau uaccaauucu gaacaaacaa uccuguucaa      600

uaucaaacau cgaaacggua auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa      660

caagagaauu uucaguaaau gcaggaguua caacacccgu cuccaccuac augcucacaa      720

auucagaauu auuaucacuu auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaaua guccgacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu agccuacguu guccaacuac ccuuauaugg aguaauagau accccaugcu      900

ggaaacuuca uaccuccccc cuaugcacaa caaacacaaa agaaggcuca aacaucugcu      960

uaacacguac agaccgaggu ugguacugug auaacgcagg auccguauca uuuuucccac     1020

aagcagaaac augcaaagua caaucaaacc gcguuuuuug ugacaccaug aacagcagaa     1080

cccucccuuc agaaguaaac cuaugcaacg ucgauauauu uaacccaaaa uacgauugca     1140

aaauaaugac aucaaaaacc gaugucucau cuucaguaau aaccucucua ggagcaauag     1200

ucucauguua cggaaaaaca aaaugcacag caaguaauaa aaauagagga auaauaaaaa     1260

cauucucuaa uggcugcgac uacguaucca auaaaggcgu ugacacagua uccguaggca     1320

acacacucua cuauguuaac aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa     1380

uuauaaacuu uuacgaccca cucguauucc caucugauga auuugacgca ucaaucucac     1440

aaguaaauga aaaaaucaau cagucccuug ccuuuauaag aaaaucagau gaacuuuuac     1500

acaacguuaa cgccggaaaa ucaacaacca auauaaugau cacaaccaua auaauaguua     1560

uaauuguaau uuuauuaucc uuaauagccg ucggacuacu acuauacugc aaagcaagau     1620

cuacacccgu aacccuauca aaagaccaac uaaguggaau aaauaacauu gcauucucaa     1680

auuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3922
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3922
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc      120

uaaccgccgu gacauucugc uucgccuccg gacaaaacau caccgaagaa uuuuaccaau      180

ccacaugcuc ggccgucagu aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu      240

ccgucaucac caucgaacuc uccaacauca aagaaaacaa augcaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacucgaca aauacaaaaa cgccgucaca gaacuccaac      360

uacuaaugca aucaacaccc gcuacaggaa gcggcuccgc caucgccagc ggcguagcug      420

ucugcaaagu ccuccaccuc gaaggugaag ucaacaaaau caaaucagcc cuacucagca      480

caaacaaagc cguuguaagc cuauccaacg gcgucuccgu acuaacauuc aaaguccuug      540

accucaagaa cuacaucgac aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa      600

uuuccaacau cgaaacagua aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca      660

cccgcgaauu uuccguuaac gccggcguua caacccccgu cuccaccuac augcucacca      720

auuccgaacu acuaucacuc auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaauc guccgccagc aaagcuauuc caucaugugc aucaucaaag      840

aggaaguccu cgccuacgua guccaacugc cccucuacgg cgucauugau acccccugcu      900

ggaaacucca caccuccccc cucugcacca caaacaccaa agaagguucc aacaucugcc      960

uaacacgaac cgacagaggc ugguacugcg acaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cuguaaaguc cagucuaacc gcgucuucug cgacacaaug aacucaagaa     1080

cccuaccuuc cgaaguaaac cucugcaacg uagacaucuu caacccuaaa uacgacugca     1140

aaaucaugac uucaaaaaca gacguaagcu cuuccguaau cacuucccuc ggcgccaucg     1200

uauccugcua cgguaaaacc aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa     1260

ccuucuccaa cggcugcgac uacguaucua acaaaggcgu cgacaccguc uccgucggca     1320

acacccucua uuacguaaac aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa     1380

ucauaaacuu cuaugaccca cucgucuucc cuucagacga auuugaugcc agcaucagcc     1440

aagucaacga aaaaaucaac caaucacucg ccuucauccg caaaagcgac gaacuccuuc     1500

acaacgucaa cgcaggcaaa ucaaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucguuau ccuacucagc cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu     1620

ccacccccgu cacccucagu aaagaccaac ucagcggaau caacaacaua gcauucucca     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3923
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3923
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3924
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3924
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3925
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3925
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3926
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3926
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcuuucucaa     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3927
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3927
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3928
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3928
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3929
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3929
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uacuaaaagc caaugcaaua acaaccauac      120

uaaccgccgu aacauuuugu uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau      180

caacaugcuc agcaguauca aaaggauacu uauccgcucu aagaacagga ugguacacaa      240

guguaauuac aauagagcuc ucaaacauaa aagaaaacaa augcaaugga acugacgcaa      300

aaguuaaacu uauaaaacaa gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac      360

uccuaaugca auccacaccu gcuaccgguu ccggaucagc cauagcaucu ggaguagccg      420

uaugcaaagu ccuccaccua gaaggagaag uaaauaaaau caaaucagca cuauuaucua      480

ccaauaaagc aguugucuca cuauccaaug gcguaucagu acuaacauuc aaaguauuag      540

accuuaaaaa cuacauagac aaacaacuau uaccaauucu gaacaaacaa uccuguucaa      600

uaucaaacau cgaaacggua auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa      660

caagagaauu uucaguaaau gcaggaguua caacacccgu cuccaccuac augcucacaa      720

auucagaauu auuaucacuu auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaaua guccgacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu agccuacguu guccaacuac ccuuauaugg aguaauagau accccaugcu      900

ggaaacuuca uaccuccccc cuaugcacaa caaacacaaa agaaggcuca aacaucugcu      960

uaacacguac agaccgaggu ugguacugug auaacgcagg auccguauca uuuuucccac     1020

aagcagaaac augcaaagua caaucaaacc gcguuuuuug ugacaccaug aacagcagaa     1080

cccucccuuc agaaguaaac cuaugcaacg ucgauauauu uaacccaaaa uacgauugca     1140

aaauaaugac aucaaaaacc gaugucucau cuucaguaau aaccucucua ggagcaauag     1200

ucucauguua cggaaaaaca aaaugcacag caaguaauaa aaauagagga auaauaaaaa     1260

cauucucuaa uggcugcgac uacguaucca auaaaggcgu ugacacagua uccguaggca     1320

acacacucua cuauguuaac aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa     1380

uuauaaacuu uuacgaccca cucguauucc caucugauga auuugacgca ucaaucucac     1440

aaguaaauga aaaaaucaau cagucccuug ccuuuauaag aaaaucagau gaacuuuuac     1500

acaacguuaa cgccggaaaa ucaacaacca auauaaugau cacaaccaua auaauaguua     1560

uaauuguaau uuuauuaucc uuaauagccg ucggacuacu acuauacugc aaagcaagau     1620

cuacacccgu aacccuauca aaagaccaac uaaguggaau aaauaacauu gcauucucaa     1680

auuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3930
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3930
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc      120

uaaccgccgu gacauucugc uucgccuccg gacaaaacau caccgaagaa uuuuaccaau      180

ccacaugcuc ggccgucagu aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu      240

ccgucaucac caucgaacuc uccaacauca aagaaaacaa augcaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacucgaca aauacaaaaa cgccgucaca gaacuccaac      360

uacuaaugca aucaacaccc gcuacaggaa gcggcuccgc caucgccagc ggcguagcug      420

ucugcaaagu ccuccaccuc gaaggugaag ucaacaaaau caaaucagcc cuacucagca      480

caaacaaagc cguuguaagc cuauccaacg gcgucuccgu acuaacauuc aaaguccuug      540

accucaagaa cuacaucgac aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa      600

uuuccaacau cgaaacagua aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca      660

cccgcgaauu uuccguuaac gccggcguua caacccccgu cuccaccuac augcucacca      720

auuccgaacu acuaucacuc auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaauc guccgccagc aaagcuauuc caucaugugc aucaucaaag      840

aggaaguccu cgccuacgua guccaacugc cccucuacgg cgucauugau acccccugcu      900

ggaaacucca caccuccccc cucugcacca caaacaccaa agaagguucc aacaucugcc      960

uaacacgaac cgacagaggc ugguacugcg acaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cuguaaaguc cagucuaacc gcgucuucug cgacacaaug aacucaagaa     1080

cccuaccuuc cgaaguaaac cucugcaacg uagacaucuu caacccuaaa uacgacugca     1140

aaaucaugac uucaaaaaca gacguaagcu cuuccguaau cacuucccuc ggcgccaucg     1200

uauccugcua cgguaaaacc aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa     1260

ccuucuccaa cggcugcgac uacguaucua acaaaggcgu cgacaccguc uccgucggca     1320

acacccucua uuacguaaac aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa     1380

ucauaaacuu cuaugaccca cucgucuucc cuucagacga auuugaugcc agcaucagcc     1440

aagucaacga aaaaaucaac caaucacucg ccuucauccg caaaagcgac gaacuccuuc     1500

acaacgucaa cgcaggcaaa ucaaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucguuau ccuacucagc cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu     1620

ccacccccgu cacccucagu aaagaccaac ucagcggaau caacaacaua gcauucucca     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  3931
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3931
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3932
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3932
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3933
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3933
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3934
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3934
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcuu ucucaaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3935
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3935
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3936
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3936
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3937
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3937
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauacu aaaagccaau gcaauaacaa ccauacuaac cgccguaaca      180

uuuuguuucg caucagguca aaacauaacc gaagaauuuu aucaaucaac augcucagca      240

guaucaaaag gauacuuauc cgcucuaaga acaggauggu acacaagugu aauuacaaua      300

gagcucucaa acauaaaaga aaacaaaugc aauggaacug acgcaaaagu uaaacuuaua      360

aaacaagaac uagauaaaua uaaaaaugca guaaccgaau uacaacuccu aaugcaaucc      420

acaccugcua ccgguuccgg aucagccaua gcaucuggag uagccguaug caaaguccuc      480

caccuagaag gagaaguaaa uaaaaucaaa ucagcacuau uaucuaccaa uaaagcaguu      540

gucucacuau ccaauggcgu aucaguacua acauucaaag uauuagaccu uaaaaacuac      600

auagacaaac aacuauuacc aauucugaac aaacaauccu guucaauauc aaacaucgaa      660

acgguaauag aauuucaaca aaaaaauaac agauuacuug aaauaacaag agaauuuuca      720

guaaaugcag gaguuacaac acccgucucc accuacaugc ucacaaauuc agaauuauua      780

ucacuuauaa acgacaugcc aauaacuaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaauagucc gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccuagcc      900

uacguugucc aacuacccuu auauggagua auagauaccc caugcuggaa acuucauacc      960

uccccccuau gcacaacaaa cacaaaagaa ggcucaaaca ucugcuuaac acguacagac     1020

cgagguuggu acugugauaa cgcaggaucc guaucauuuu ucccacaagc agaaacaugc     1080

aaaguacaau caaaccgcgu uuuuugugac accaugaaca gcagaacccu cccuucagaa     1140

guaaaccuau gcaacgucga uauauuuaac ccaaaauacg auugcaaaau aaugacauca     1200

aaaaccgaug ucucaucuuc aguaauaacc ucucuaggag caauagucuc auguuacgga     1260

aaaacaaaau gcacagcaag uaauaaaaau agaggaauaa uaaaaacauu cucuaauggc     1320

ugcgacuacg uauccaauaa aggcguugac acaguauccg uaggcaacac acucuacuau     1380

guuaacaaac aagaaggaaa aaguuuauac guuaaaggag aaccaauuau aaacuuuuac     1440

gacccacucg uauucccauc ugaugaauuu gacgcaucaa ucucacaagu aaaugaaaaa     1500

aucaaucagu cccuugccuu uauaagaaaa ucagaugaac uuuuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaauau aaugaucaca accauaauaa uaguuauaau uguaauuuua     1620

uuauccuuaa uagccgucgg acuacuacua uacugcaaag caagaucuac acccguaacc     1680

cuaucaaaag accaacuaag uggaauaaau aacauugcau ucucaaauua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3938
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3938
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu aaaggcaaac gcaaucacua caauucuaac cgccgugaca      180

uucugcuucg ccuccggaca aaacaucacc gaagaauuuu accaauccac augcucggcc      240

gucaguaaag gcuaccucuc ggcucuccga accggcuggu acaccuccgu caucaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagaac uccaacuacu aaugcaauca      420

acacccgcua caggaagcgg cuccgccauc gccagcggcg uagcugucug caaaguccuc      480

caccucgaag gugaagucaa caaaaucaaa ucagcccuac ucagcacaaa caaagccguu      540

guaagccuau ccaacggcgu cuccguacua acauucaaag uccuugaccu caagaacuac      600

aucgacaaac aacuucuccc aauccuaaac aaacaaagcu gcucaauuuc caacaucgaa      660

acaguaaucg aauuucaaca aaaaaacaac cgacuccucg aaaucacccg cgaauuuucc      720

guuaacgccg gcguuacaac ccccgucucc accuacaugc ucaccaauuc cgaacuacua      780

ucacucauaa acgacaugcc uaucacaaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaaucgucc gccagcaaag cuauuccauc augugcauca ucaaagagga aguccucgcc      900

uacguagucc aacugccccu cuacggcguc auugauaccc ccugcuggaa acuccacacc      960

uccccccucu gcaccacaaa caccaaagaa gguuccaaca ucugccuaac acgaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gucuccuucu ucccccaagc agaaaccugu     1080

aaaguccagu cuaaccgcgu cuucugcgac acaaugaacu caagaacccu accuuccgaa     1140

guaaaccucu gcaacguaga caucuucaac ccuaaauacg acugcaaaau caugacuuca     1200

aaaacagacg uaagcucuuc cguaaucacu ucccucggcg ccaucguauc cugcuacggu     1260

aaaaccaaau gcaccgccuc caacaaaaac cgagggauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg uaucuaacaa aggcgucgac accgucuccg ucggcaacac ccucuauuac     1380

guaaacaaac aagagggcaa aucacuauac gucaaaggcg agccaaucau aaacuucuau     1440

gacccacucg ucuucccuuc agacgaauuu gaugccagca ucagccaagu caacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa agcgacgaac uccuucacaa cgucaacgca     1560

ggcaaaucaa ccaccaacau caugaucacc accaucauca ucgucaucau cguuauccua     1620

cucagccuca ucgcaguugg ucuucuccuu uacugcaaag cccgcuccac ccccgucacc     1680

cucaguaaag accaacucag cggaaucaac aacauagcau ucuccaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  3939
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3939
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3940
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3940
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3941
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3941
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3942
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3942
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cuuucucaaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3943
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3943
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3944
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3944
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3945
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3945
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau acuaaaagcc      120

aaugcaauaa caaccauacu aaccgccgua acauuuuguu ucgcaucagg ucaaaacaua      180

accgaagaau uuuaucaauc aacaugcuca gcaguaucaa aaggauacuu auccgcucua      240

agaacaggau gguacacaag uguaauuaca auagagcucu caaacauaaa agaaaacaaa      300

ugcaauggaa cugacgcaaa aguuaaacuu auaaaacaag aacuagauaa auauaaaaau      360

gcaguaaccg aauuacaacu ccuaaugcaa uccacaccug cuaccgguuc cggaucagcc      420

auagcaucug gaguagccgu augcaaaguc cuccaccuag aaggagaagu aaauaaaauc      480

aaaucagcac uauuaucuac caauaaagca guugucucac uauccaaugg cguaucagua      540

cuaacauuca aaguauuaga ccuuaaaaac uacauagaca aacaacuauu accaauucug      600

aacaaacaau ccuguucaau aucaaacauc gaaacgguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaauaac aagagaauuu ucaguaaaug caggaguuac aacacccguc      720

uccaccuaca ugcucacaaa uucagaauua uuaucacuua uaaacgacau gccaauaacu      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaauag uccgacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccua gccuacguug uccaacuacc cuuauaugga      900

guaauagaua ccccaugcug gaaacuucau accucccccc uaugcacaac aaacacaaaa      960

gaaggcucaa acaucugcuu aacacguaca gaccgagguu gguacuguga uaacgcagga     1020

uccguaucau uuuucccaca agcagaaaca ugcaaaguac aaucaaaccg cguuuuuugu     1080

gacaccauga acagcagaac ccucccuuca gaaguaaacc uaugcaacgu cgauauauuu     1140

aacccaaaau acgauugcaa aauaaugaca ucaaaaaccg augucucauc uucaguaaua     1200

accucucuag gagcaauagu cucauguuac ggaaaaacaa aaugcacagc aaguaauaaa     1260

aauagaggaa uaauaaaaac auucucuaau ggcugcgacu acguauccaa uaaaggcguu     1320

gacacaguau ccguaggcaa cacacucuac uauguuaaca aacaagaagg aaaaaguuua     1380

uacguuaaag gagaaccaau uauaaacuuu uacgacccac ucguauuccc aucugaugaa     1440

uuugacgcau caaucucaca aguaaaugaa aaaaucaauc agucccuugc cuuuauaaga     1500

aaaucagaug aacuuuuaca caacguuaac gccggaaaau caacaaccaa uauaaugauc     1560

acaaccauaa uaauaguuau aauuguaauu uuauuauccu uaauagccgu cggacuacua     1620

cuauacugca aagcaagauc uacacccgua acccuaucaa aagaccaacu aaguggaaua     1680

aauaacauug cauucucaaa uuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3946
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3946
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuaaaggca      120

aacgcaauca cuacaauucu aaccgccgug acauucugcu ucgccuccgg acaaaacauc      180

accgaagaau uuuaccaauc cacaugcucg gccgucagua aaggcuaccu cucggcucuc      240

cgaaccggcu gguacaccuc cgucaucacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgccaa agucaaacua aucaaacaag aacucgacaa auacaaaaac      360

gccgucacag aacuccaacu acuaaugcaa ucaacacccg cuacaggaag cggcuccgcc      420

aucgccagcg gcguagcugu cugcaaaguc cuccaccucg aaggugaagu caacaaaauc      480

aaaucagccc uacucagcac aaacaaagcc guuguaagcc uauccaacgg cgucuccgua      540

cuaacauuca aaguccuuga ccucaagaac uacaucgaca aacaacuucu cccaauccua      600

aacaaacaaa gcugcucaau uuccaacauc gaaacaguaa ucgaauuuca acaaaaaaac      660

aaccgacucc ucgaaaucac ccgcgaauuu uccguuaacg ccggcguuac aacccccguc      720

uccaccuaca ugcucaccaa uuccgaacua cuaucacuca uaaacgacau gccuaucaca      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaaucg uccgccagca aagcuauucc      840

aucaugugca ucaucaaaga ggaaguccuc gccuacguag uccaacugcc ccucuacggc      900

gucauugaua cccccugcug gaaacuccac accucccccc ucugcaccac aaacaccaaa      960

gaagguucca acaucugccu aacacgaacc gacagaggcu gguacugcga caacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc uguaaagucc agucuaaccg cgucuucugc     1080

gacacaauga acucaagaac ccuaccuucc gaaguaaacc ucugcaacgu agacaucuuc     1140

aacccuaaau acgacugcaa aaucaugacu ucaaaaacag acguaagcuc uuccguaauc     1200

acuucccucg gcgccaucgu auccugcuac gguaaaacca aaugcaccgc cuccaacaaa     1260

aaccgaggga ucauaaaaac cuucuccaac ggcugcgacu acguaucuaa caaaggcguc     1320

gacaccgucu ccgucggcaa cacccucuau uacguaaaca aacaagaggg caaaucacua     1380

uacgucaaag gcgagccaau cauaaacuuc uaugacccac ucgucuuccc uucagacgaa     1440

uuugaugcca gcaucagcca agucaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaaagcgacg aacuccuuca caacgucaac gcaggcaaau caaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucguuauc cuacucagcc ucaucgcagu uggucuucuc     1620

cuuuacugca aagcccgcuc cacccccguc acccucagua aagaccaacu cagcggaauc     1680

aacaacauag cauucuccaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  3947
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3947
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3948
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3948
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3949
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3949
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3950
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3950
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcuu ucucaaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3951
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3951
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3952
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3952
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3953
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3953
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauacu aaaagccaau gcaauaacaa ccauacuaac cgccguaaca      180

uuuuguuucg caucagguca aaacauaacc gaagaauuuu aucaaucaac augcucagca      240

guaucaaaag gauacuuauc cgcucuaaga acaggauggu acacaagugu aauuacaaua      300

gagcucucaa acauaaaaga aaacaaaugc aauggaacug acgcaaaagu uaaacuuaua      360

aaacaagaac uagauaaaua uaaaaaugca guaaccgaau uacaacuccu aaugcaaucc      420

acaccugcua ccgguuccgg aucagccaua gcaucuggag uagccguaug caaaguccuc      480

caccuagaag gagaaguaaa uaaaaucaaa ucagcacuau uaucuaccaa uaaagcaguu      540

gucucacuau ccaauggcgu aucaguacua acauucaaag uauuagaccu uaaaaacuac      600

auagacaaac aacuauuacc aauucugaac aaacaauccu guucaauauc aaacaucgaa      660

acgguaauag aauuucaaca aaaaaauaac agauuacuug aaauaacaag agaauuuuca      720

guaaaugcag gaguuacaac acccgucucc accuacaugc ucacaaauuc agaauuauua      780

ucacuuauaa acgacaugcc aauaacuaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaauagucc gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccuagcc      900

uacguugucc aacuacccuu auauggagua auagauaccc caugcuggaa acuucauacc      960

uccccccuau gcacaacaaa cacaaaagaa ggcucaaaca ucugcuuaac acguacagac     1020

cgagguuggu acugugauaa cgcaggaucc guaucauuuu ucccacaagc agaaacaugc     1080

aaaguacaau caaaccgcgu uuuuugugac accaugaaca gcagaacccu cccuucagaa     1140

guaaaccuau gcaacgucga uauauuuaac ccaaaauacg auugcaaaau aaugacauca     1200

aaaaccgaug ucucaucuuc aguaauaacc ucucuaggag caauagucuc auguuacgga     1260

aaaacaaaau gcacagcaag uaauaaaaau agaggaauaa uaaaaacauu cucuaauggc     1320

ugcgacuacg uauccaauaa aggcguugac acaguauccg uaggcaacac acucuacuau     1380

guuaacaaac aagaaggaaa aaguuuauac guuaaaggag aaccaauuau aaacuuuuac     1440

gacccacucg uauucccauc ugaugaauuu gacgcaucaa ucucacaagu aaaugaaaaa     1500

aucaaucagu cccuugccuu uauaagaaaa ucagaugaac uuuuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaauau aaugaucaca accauaauaa uaguuauaau uguaauuuua     1620

uuauccuuaa uagccgucgg acuacuacua uacugcaaag caagaucuac acccguaacc     1680

cuaucaaaag accaacuaag uggaauaaau aacauugcau ucucaaauua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3954
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3954
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu aaaggcaaac gcaaucacua caauucuaac cgccgugaca      180

uucugcuucg ccuccggaca aaacaucacc gaagaauuuu accaauccac augcucggcc      240

gucaguaaag gcuaccucuc ggcucuccga accggcuggu acaccuccgu caucaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagaac uccaacuacu aaugcaauca      420

acacccgcua caggaagcgg cuccgccauc gccagcggcg uagcugucug caaaguccuc      480

caccucgaag gugaagucaa caaaaucaaa ucagcccuac ucagcacaaa caaagccguu      540

guaagccuau ccaacggcgu cuccguacua acauucaaag uccuugaccu caagaacuac      600

aucgacaaac aacuucuccc aauccuaaac aaacaaagcu gcucaauuuc caacaucgaa      660

acaguaaucg aauuucaaca aaaaaacaac cgacuccucg aaaucacccg cgaauuuucc      720

guuaacgccg gcguuacaac ccccgucucc accuacaugc ucaccaauuc cgaacuacua      780

ucacucauaa acgacaugcc uaucacaaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaaucgucc gccagcaaag cuauuccauc augugcauca ucaaagagga aguccucgcc      900

uacguagucc aacugccccu cuacggcguc auugauaccc ccugcuggaa acuccacacc      960

uccccccucu gcaccacaaa caccaaagaa gguuccaaca ucugccuaac acgaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gucuccuucu ucccccaagc agaaaccugu     1080

aaaguccagu cuaaccgcgu cuucugcgac acaaugaacu caagaacccu accuuccgaa     1140

guaaaccucu gcaacguaga caucuucaac ccuaaauacg acugcaaaau caugacuuca     1200

aaaacagacg uaagcucuuc cguaaucacu ucccucggcg ccaucguauc cugcuacggu     1260

aaaaccaaau gcaccgccuc caacaaaaac cgagggauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg uaucuaacaa aggcgucgac accgucuccg ucggcaacac ccucuauuac     1380

guaaacaaac aagagggcaa aucacuauac gucaaaggcg agccaaucau aaacuucuau     1440

gacccacucg ucuucccuuc agacgaauuu gaugccagca ucagccaagu caacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa agcgacgaac uccuucacaa cgucaacgca     1560

ggcaaaucaa ccaccaacau caugaucacc accaucauca ucgucaucau cguuauccua     1620

cucagccuca ucgcaguugg ucuucuccuu uacugcaaag cccgcuccac ccccgucacc     1680

cucaguaaag accaacucag cggaaucaac aacauagcau ucuccaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  3955
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3955
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3956
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3956
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3957
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3957
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3958
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3958
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cuuucucaaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3959
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3959
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3960
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3960
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3961
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3961
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau acuaaaagcc      120

aaugcaauaa caaccauacu aaccgccgua acauuuuguu ucgcaucagg ucaaaacaua      180

accgaagaau uuuaucaauc aacaugcuca gcaguaucaa aaggauacuu auccgcucua      240

agaacaggau gguacacaag uguaauuaca auagagcucu caaacauaaa agaaaacaaa      300

ugcaauggaa cugacgcaaa aguuaaacuu auaaaacaag aacuagauaa auauaaaaau      360

gcaguaaccg aauuacaacu ccuaaugcaa uccacaccug cuaccgguuc cggaucagcc      420

auagcaucug gaguagccgu augcaaaguc cuccaccuag aaggagaagu aaauaaaauc      480

aaaucagcac uauuaucuac caauaaagca guugucucac uauccaaugg cguaucagua      540

cuaacauuca aaguauuaga ccuuaaaaac uacauagaca aacaacuauu accaauucug      600

aacaaacaau ccuguucaau aucaaacauc gaaacgguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaauaac aagagaauuu ucaguaaaug caggaguuac aacacccguc      720

uccaccuaca ugcucacaaa uucagaauua uuaucacuua uaaacgacau gccaauaacu      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaauag uccgacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccua gccuacguug uccaacuacc cuuauaugga      900

guaauagaua ccccaugcug gaaacuucau accucccccc uaugcacaac aaacacaaaa      960

gaaggcucaa acaucugcuu aacacguaca gaccgagguu gguacuguga uaacgcagga     1020

uccguaucau uuuucccaca agcagaaaca ugcaaaguac aaucaaaccg cguuuuuugu     1080

gacaccauga acagcagaac ccucccuuca gaaguaaacc uaugcaacgu cgauauauuu     1140

aacccaaaau acgauugcaa aauaaugaca ucaaaaaccg augucucauc uucaguaaua     1200

accucucuag gagcaauagu cucauguuac ggaaaaacaa aaugcacagc aaguaauaaa     1260

aauagaggaa uaauaaaaac auucucuaau ggcugcgacu acguauccaa uaaaggcguu     1320

gacacaguau ccguaggcaa cacacucuac uauguuaaca aacaagaagg aaaaaguuua     1380

uacguuaaag gagaaccaau uauaaacuuu uacgacccac ucguauuccc aucugaugaa     1440

uuugacgcau caaucucaca aguaaaugaa aaaaucaauc agucccuugc cuuuauaaga     1500

aaaucagaug aacuuuuaca caacguuaac gccggaaaau caacaaccaa uauaaugauc     1560

acaaccauaa uaauaguuau aauuguaauu uuauuauccu uaauagccgu cggacuacua     1620

cuauacugca aagcaagauc uacacccgua acccuaucaa aagaccaacu aaguggaaua     1680

aauaacauug cauucucaaa uuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3962
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3962
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuaaaggca      120

aacgcaauca cuacaauucu aaccgccgug acauucugcu ucgccuccgg acaaaacauc      180

accgaagaau uuuaccaauc cacaugcucg gccgucagua aaggcuaccu cucggcucuc      240

cgaaccggcu gguacaccuc cgucaucacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgccaa agucaaacua aucaaacaag aacucgacaa auacaaaaac      360

gccgucacag aacuccaacu acuaaugcaa ucaacacccg cuacaggaag cggcuccgcc      420

aucgccagcg gcguagcugu cugcaaaguc cuccaccucg aaggugaagu caacaaaauc      480

aaaucagccc uacucagcac aaacaaagcc guuguaagcc uauccaacgg cgucuccgua      540

cuaacauuca aaguccuuga ccucaagaac uacaucgaca aacaacuucu cccaauccua      600

aacaaacaaa gcugcucaau uuccaacauc gaaacaguaa ucgaauuuca acaaaaaaac      660

aaccgacucc ucgaaaucac ccgcgaauuu uccguuaacg ccggcguuac aacccccguc      720

uccaccuaca ugcucaccaa uuccgaacua cuaucacuca uaaacgacau gccuaucaca      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaaucg uccgccagca aagcuauucc      840

aucaugugca ucaucaaaga ggaaguccuc gccuacguag uccaacugcc ccucuacggc      900

gucauugaua cccccugcug gaaacuccac accucccccc ucugcaccac aaacaccaaa      960

gaagguucca acaucugccu aacacgaacc gacagaggcu gguacugcga caacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc uguaaagucc agucuaaccg cgucuucugc     1080

gacacaauga acucaagaac ccuaccuucc gaaguaaacc ucugcaacgu agacaucuuc     1140

aacccuaaau acgacugcaa aaucaugacu ucaaaaacag acguaagcuc uuccguaauc     1200

acuucccucg gcgccaucgu auccugcuac gguaaaacca aaugcaccgc cuccaacaaa     1260

aaccgaggga ucauaaaaac cuucuccaac ggcugcgacu acguaucuaa caaaggcguc     1320

gacaccgucu ccgucggcaa cacccucuau uacguaaaca aacaagaggg caaaucacua     1380

uacgucaaag gcgagccaau cauaaacuuc uaugacccac ucgucuuccc uucagacgaa     1440

uuugaugcca gcaucagcca agucaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaaagcgacg aacuccuuca caacgucaac gcaggcaaau caaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucguuauc cuacucagcc ucaucgcagu uggucuucuc     1620

cuuuacugca aagcccgcuc cacccccguc acccucagua aagaccaacu cagcggaauc     1680

aacaacauag cauucuccaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  3963
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3963
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3964
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3964
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3965
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3965
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3966
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3966
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cuuucucaaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3967
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3967
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3968
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3968
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3969
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3969
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau acuaaaagcc      120

aaugcaauaa caaccauacu aaccgccgua acauuuuguu ucgcaucagg ucaaaacaua      180

accgaagaau uuuaucaauc aacaugcuca gcaguaucaa aaggauacuu auccgcucua      240

agaacaggau gguacacaag uguaauuaca auagagcucu caaacauaaa agaaaacaaa      300

ugcaauggaa cugacgcaaa aguuaaacuu auaaaacaag aacuagauaa auauaaaaau      360

gcaguaaccg aauuacaacu ccuaaugcaa uccacaccug cuaccgguuc cggaucagcc      420

auagcaucug gaguagccgu augcaaaguc cuccaccuag aaggagaagu aaauaaaauc      480

aaaucagcac uauuaucuac caauaaagca guugucucac uauccaaugg cguaucagua      540

cuaacauuca aaguauuaga ccuuaaaaac uacauagaca aacaacuauu accaauucug      600

aacaaacaau ccuguucaau aucaaacauc gaaacgguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaauaac aagagaauuu ucaguaaaug caggaguuac aacacccguc      720

uccaccuaca ugcucacaaa uucagaauua uuaucacuua uaaacgacau gccaauaacu      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaauag uccgacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccua gccuacguug uccaacuacc cuuauaugga      900

guaauagaua ccccaugcug gaaacuucau accucccccc uaugcacaac aaacacaaaa      960

gaaggcucaa acaucugcuu aacacguaca gaccgagguu gguacuguga uaacgcagga     1020

uccguaucau uuuucccaca agcagaaaca ugcaaaguac aaucaaaccg cguuuuuugu     1080

gacaccauga acagcagaac ccucccuuca gaaguaaacc uaugcaacgu cgauauauuu     1140

aacccaaaau acgauugcaa aauaaugaca ucaaaaaccg augucucauc uucaguaaua     1200

accucucuag gagcaauagu cucauguuac ggaaaaacaa aaugcacagc aaguaauaaa     1260

aauagaggaa uaauaaaaac auucucuaau ggcugcgacu acguauccaa uaaaggcguu     1320

gacacaguau ccguaggcaa cacacucuac uauguuaaca aacaagaagg aaaaaguuua     1380

uacguuaaag gagaaccaau uauaaacuuu uacgacccac ucguauuccc aucugaugaa     1440

uuugacgcau caaucucaca aguaaaugaa aaaaucaauc agucccuugc cuuuauaaga     1500

aaaucagaug aacuuuuaca caacguuaac gccggaaaau caacaaccaa uauaaugauc     1560

acaaccauaa uaauaguuau aauuguaauu uuauuauccu uaauagccgu cggacuacua     1620

cuauacugca aagcaagauc uacacccgua acccuaucaa aagaccaacu aaguggaaua     1680

aauaacauug cauucucaaa uuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3970
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3970
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuaaaggca      120

aacgcaauca cuacaauucu aaccgccgug acauucugcu ucgccuccgg acaaaacauc      180

accgaagaau uuuaccaauc cacaugcucg gccgucagua aaggcuaccu cucggcucuc      240

cgaaccggcu gguacaccuc cgucaucacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgccaa agucaaacua aucaaacaag aacucgacaa auacaaaaac      360

gccgucacag aacuccaacu acuaaugcaa ucaacacccg cuacaggaag cggcuccgcc      420

aucgccagcg gcguagcugu cugcaaaguc cuccaccucg aaggugaagu caacaaaauc      480

aaaucagccc uacucagcac aaacaaagcc guuguaagcc uauccaacgg cgucuccgua      540

cuaacauuca aaguccuuga ccucaagaac uacaucgaca aacaacuucu cccaauccua      600

aacaaacaaa gcugcucaau uuccaacauc gaaacaguaa ucgaauuuca acaaaaaaac      660

aaccgacucc ucgaaaucac ccgcgaauuu uccguuaacg ccggcguuac aacccccguc      720

uccaccuaca ugcucaccaa uuccgaacua cuaucacuca uaaacgacau gccuaucaca      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaaucg uccgccagca aagcuauucc      840

aucaugugca ucaucaaaga ggaaguccuc gccuacguag uccaacugcc ccucuacggc      900

gucauugaua cccccugcug gaaacuccac accucccccc ucugcaccac aaacaccaaa      960

gaagguucca acaucugccu aacacgaacc gacagaggcu gguacugcga caacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc uguaaagucc agucuaaccg cgucuucugc     1080

gacacaauga acucaagaac ccuaccuucc gaaguaaacc ucugcaacgu agacaucuuc     1140

aacccuaaau acgacugcaa aaucaugacu ucaaaaacag acguaagcuc uuccguaauc     1200

acuucccucg gcgccaucgu auccugcuac gguaaaacca aaugcaccgc cuccaacaaa     1260

aaccgaggga ucauaaaaac cuucuccaac ggcugcgacu acguaucuaa caaaggcguc     1320

gacaccgucu ccgucggcaa cacccucuau uacguaaaca aacaagaggg caaaucacua     1380

uacgucaaag gcgagccaau cauaaacuuc uaugacccac ucgucuuccc uucagacgaa     1440

uuugaugcca gcaucagcca agucaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaaagcgacg aacuccuuca caacgucaac gcaggcaaau caaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucguuauc cuacucagcc ucaucgcagu uggucuucuc     1620

cuuuacugca aagcccgcuc cacccccguc acccucagua aagaccaacu cagcggaauc     1680

aacaacauag cauucuccaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  3971
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3971
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3972
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3972
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3973
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3973
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3974
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3974
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcuuucu caaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3975
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3975
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3976
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3976
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3977
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3977
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauacuaaa agccaaugca      120

auaacaacca uacuaaccgc cguaacauuu uguuucgcau caggucaaaa cauaaccgaa      180

gaauuuuauc aaucaacaug cucagcagua ucaaaaggau acuuauccgc ucuaagaaca      240

ggaugguaca caaguguaau uacaauagag cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacugacg caaaaguuaa acuuauaaaa caagaacuag auaaauauaa aaaugcagua      360

accgaauuac aacuccuaau gcaauccaca ccugcuaccg guuccggauc agccauagca      420

ucuggaguag ccguaugcaa aguccuccac cuagaaggag aaguaaauaa aaucaaauca      480

gcacuauuau cuaccaauaa agcaguuguc ucacuaucca auggcguauc aguacuaaca      540

uucaaaguau uagaccuuaa aaacuacaua gacaaacaac uauuaccaau ucugaacaaa      600

caauccuguu caauaucaaa caucgaaacg guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa uaacaagaga auuuucagua aaugcaggag uuacaacacc cgucuccacc      720

uacaugcuca caaauucaga auuauuauca cuuauaaacg acaugccaau aacuaacgac      780

caaaaaaaac uaaugucaaa caauguccaa auaguccgac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccuagccuac guuguccaac uacccuuaua uggaguaaua      900

gauaccccau gcuggaaacu ucauaccucc ccccuaugca caacaaacac aaaagaaggc      960

ucaaacaucu gcuuaacacg uacagaccga gguugguacu gugauaacgc aggauccgua     1020

ucauuuuucc cacaagcaga aacaugcaaa guacaaucaa accgcguuuu uugugacacc     1080

augaacagca gaacccuccc uucagaagua aaccuaugca acgucgauau auuuaaccca     1140

aaauacgauu gcaaaauaau gacaucaaaa accgaugucu caucuucagu aauaaccucu     1200

cuaggagcaa uagucucaug uuacggaaaa acaaaaugca cagcaaguaa uaaaaauaga     1260

ggaauaauaa aaacauucuc uaauggcugc gacuacguau ccaauaaagg cguugacaca     1320

guauccguag gcaacacacu cuacuauguu aacaaacaag aaggaaaaag uuuauacguu     1380

aaaggagaac caauuauaaa cuuuuacgac ccacucguau ucccaucuga ugaauuugac     1440

gcaucaaucu cacaaguaaa ugaaaaaauc aaucaguccc uugccuuuau aagaaaauca     1500

gaugaacuuu uacacaacgu uaacgccgga aaaucaacaa ccaauauaau gaucacaacc     1560

auaauaauag uuauaauugu aauuuuauua uccuuaauag ccgucggacu acuacuauac     1620

ugcaaagcaa gaucuacacc cguaacccua ucaaaagacc aacuaagugg aauaaauaac     1680

auugcauucu caaauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3978
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3978
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuaaa ggcaaacgca      120

aucacuacaa uucuaaccgc cgugacauuc ugcuucgccu ccggacaaaa caucaccgaa      180

gaauuuuacc aauccacaug cucggccguc aguaaaggcu accucucggc ucuccgaacc      240

ggcugguaca ccuccgucau caccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacucg acaaauacaa aaacgccguc      360

acagaacucc aacuacuaau gcaaucaaca cccgcuacag gaagcggcuc cgccaucgcc      420

agcggcguag cugucugcaa aguccuccac cucgaaggug aagucaacaa aaucaaauca      480

gcccuacuca gcacaaacaa agccguugua agccuaucca acggcgucuc cguacuaaca      540

uucaaagucc uugaccucaa gaacuacauc gacaaacaac uucucccaau ccuaaacaaa      600

caaagcugcu caauuuccaa caucgaaaca guaaucgaau uucaacaaaa aaacaaccga      660

cuccucgaaa ucacccgcga auuuuccguu aacgccggcg uuacaacccc cgucuccacc      720

uacaugcuca ccaauuccga acuacuauca cucauaaacg acaugccuau cacaaacgac      780

caaaaaaaac uaaugucaaa caauguccaa aucguccgcc agcaaagcua uuccaucaug      840

ugcaucauca aagaggaagu ccucgccuac guaguccaac ugccccucua cggcgucauu      900

gauacccccu gcuggaaacu ccacaccucc ccccucugca ccacaaacac caaagaaggu      960

uccaacaucu gccuaacacg aaccgacaga ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccuguaaa guccagucua accgcgucuu cugcgacaca     1080

augaacucaa gaacccuacc uuccgaagua aaccucugca acguagacau cuucaacccu     1140

aaauacgacu gcaaaaucau gacuucaaaa acagacguaa gcucuuccgu aaucacuucc     1200

cucggcgcca ucguauccug cuacgguaaa accaaaugca ccgccuccaa caaaaaccga     1260

gggaucauaa aaaccuucuc caacggcugc gacuacguau cuaacaaagg cgucgacacc     1320

gucuccgucg gcaacacccu cuauuacgua aacaaacaag agggcaaauc acuauacguc     1380

aaaggcgagc caaucauaaa cuucuaugac ccacucgucu ucccuucaga cgaauuugau     1440

gccagcauca gccaagucaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaagc     1500

gacgaacucc uucacaacgu caacgcaggc aaaucaacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu uauccuacuc agccucaucg caguuggucu ucuccuuuac     1620

ugcaaagccc gcuccacccc cgucacccuc aguaaagacc aacucagcgg aaucaacaac     1680

auagcauucu ccaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  3979
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3979
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3980
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3980
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3981
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3981
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3982
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3982
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcuuucuc aaacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3983
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3983
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3984
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3984
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3985
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3985
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauacuaaaa      120

gccaaugcaa uaacaaccau acuaaccgcc guaacauuuu guuucgcauc aggucaaaac      180

auaaccgaag aauuuuauca aucaacaugc ucagcaguau caaaaggaua cuuauccgcu      240

cuaagaacag gaugguacac aaguguaauu acaauagagc ucucaaacau aaaagaaaac      300

aaaugcaaug gaacugacgc aaaaguuaaa cuuauaaaac aagaacuaga uaaauauaaa      360

aaugcaguaa ccgaauuaca acuccuaaug caauccacac cugcuaccgg uuccggauca      420

gccauagcau cuggaguagc cguaugcaaa guccuccacc uagaaggaga aguaaauaaa      480

aucaaaucag cacuauuauc uaccaauaaa gcaguugucu cacuauccaa uggcguauca      540

guacuaacau ucaaaguauu agaccuuaaa aacuacauag acaaacaacu auuaccaauu      600

cugaacaaac aauccuguuc aauaucaaac aucgaaacgg uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau aacaagagaa uuuucaguaa augcaggagu uacaacaccc      720

gucuccaccu acaugcucac aaauucagaa uuauuaucac uuauaaacga caugccaaua      780

acuaacgacc aaaaaaaacu aaugucaaac aauguccaaa uaguccgaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cuagccuacg uuguccaacu acccuuauau      900

ggaguaauag auaccccaug cuggaaacuu cauaccuccc cccuaugcac aacaaacaca      960

aaagaaggcu caaacaucug cuuaacacgu acagaccgag guugguacug ugauaacgca     1020

ggauccguau cauuuuuccc acaagcagaa acaugcaaag uacaaucaaa ccgcguuuuu     1080

ugugacacca ugaacagcag aacccucccu ucagaaguaa accuaugcaa cgucgauaua     1140

uuuaacccaa aauacgauug caaaauaaug acaucaaaaa ccgaugucuc aucuucagua     1200

auaaccucuc uaggagcaau agucucaugu uacggaaaaa caaaaugcac agcaaguaau     1260

aaaaauagag gaauaauaaa aacauucucu aauggcugcg acuacguauc caauaaaggc     1320

guugacacag uauccguagg caacacacuc uacuauguua acaaacaaga aggaaaaagu     1380

uuauacguua aaggagaacc aauuauaaac uuuuacgacc cacucguauu cccaucugau     1440

gaauuugacg caucaaucuc acaaguaaau gaaaaaauca aucagucccu ugccuuuaua     1500

agaaaaucag augaacuuuu acacaacguu aacgccggaa aaucaacaac caauauaaug     1560

aucacaacca uaauaauagu uauaauugua auuuuauuau ccuuaauagc cgucggacua     1620

cuacuauacu gcaaagcaag aucuacaccc guaacccuau caaaagacca acuaagugga     1680

auaaauaaca uugcauucuc aaauuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3986
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3986
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuaaag      120

gcaaacgcaa ucacuacaau ucuaaccgcc gugacauucu gcuucgccuc cggacaaaac      180

aucaccgaag aauuuuacca auccacaugc ucggccguca guaaaggcua ccucucggcu      240

cuccgaaccg gcugguacac cuccgucauc accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacucga caaauacaaa      360

aacgccguca cagaacucca acuacuaaug caaucaacac ccgcuacagg aagcggcucc      420

gccaucgcca gcggcguagc ugucugcaaa guccuccacc ucgaagguga agucaacaaa      480

aucaaaucag cccuacucag cacaaacaaa gccguuguaa gccuauccaa cggcgucucc      540

guacuaacau ucaaaguccu ugaccucaag aacuacaucg acaaacaacu ucucccaauc      600

cuaaacaaac aaagcugcuc aauuuccaac aucgaaacag uaaucgaauu ucaacaaaaa      660

aacaaccgac uccucgaaau cacccgcgaa uuuuccguua acgccggcgu uacaaccccc      720

gucuccaccu acaugcucac caauuccgaa cuacuaucac ucauaaacga caugccuauc      780

acaaacgacc aaaaaaaacu aaugucaaac aauguccaaa ucguccgcca gcaaagcuau      840

uccaucaugu gcaucaucaa agaggaaguc cucgccuacg uaguccaacu gccccucuac      900

ggcgucauug auacccccug cuggaaacuc cacaccuccc cccucugcac cacaaacacc      960

aaagaagguu ccaacaucug ccuaacacga accgacagag gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accuguaaag uccagucuaa ccgcgucuuc     1080

ugcgacacaa ugaacucaag aacccuaccu uccgaaguaa accucugcaa cguagacauc     1140

uucaacccua aauacgacug caaaaucaug acuucaaaaa cagacguaag cucuuccgua     1200

aucacuuccc ucggcgccau cguauccugc uacgguaaaa ccaaaugcac cgccuccaac     1260

aaaaaccgag ggaucauaaa aaccuucucc aacggcugcg acuacguauc uaacaaaggc     1320

gucgacaccg ucuccgucgg caacacccuc uauuacguaa acaaacaaga gggcaaauca     1380

cuauacguca aaggcgagcc aaucauaaac uucuaugacc cacucgucuu cccuucagac     1440

gaauuugaug ccagcaucag ccaagucaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaaagcg acgaacuccu ucacaacguc aacgcaggca aaucaaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguu auccuacuca gccucaucgc aguuggucuu     1620

cuccuuuacu gcaaagcccg cuccaccccc gucacccuca guaaagacca acucagcgga     1680

aucaacaaca uagcauucuc caacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  3987
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3987
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3988
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3988
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3989
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3989
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3990
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3990
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcuuucu caaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3991
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3991
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3992
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  3992
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3993
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  3993
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauacuaaa agccaaugca      120

auaacaacca uacuaaccgc cguaacauuu uguuucgcau caggucaaaa cauaaccgaa      180

gaauuuuauc aaucaacaug cucagcagua ucaaaaggau acuuauccgc ucuaagaaca      240

ggaugguaca caaguguaau uacaauagag cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacugacg caaaaguuaa acuuauaaaa caagaacuag auaaauauaa aaaugcagua      360

accgaauuac aacuccuaau gcaauccaca ccugcuaccg guuccggauc agccauagca      420

ucuggaguag ccguaugcaa aguccuccac cuagaaggag aaguaaauaa aaucaaauca      480

gcacuauuau cuaccaauaa agcaguuguc ucacuaucca auggcguauc aguacuaaca      540

uucaaaguau uagaccuuaa aaacuacaua gacaaacaac uauuaccaau ucugaacaaa      600

caauccuguu caauaucaaa caucgaaacg guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa uaacaagaga auuuucagua aaugcaggag uuacaacacc cgucuccacc      720

uacaugcuca caaauucaga auuauuauca cuuauaaacg acaugccaau aacuaacgac      780

caaaaaaaac uaaugucaaa caauguccaa auaguccgac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccuagccuac guuguccaac uacccuuaua uggaguaaua      900

gauaccccau gcuggaaacu ucauaccucc ccccuaugca caacaaacac aaaagaaggc      960

ucaaacaucu gcuuaacacg uacagaccga gguugguacu gugauaacgc aggauccgua     1020

ucauuuuucc cacaagcaga aacaugcaaa guacaaucaa accgcguuuu uugugacacc     1080

augaacagca gaacccuccc uucagaagua aaccuaugca acgucgauau auuuaaccca     1140

aaauacgauu gcaaaauaau gacaucaaaa accgaugucu caucuucagu aauaaccucu     1200

cuaggagcaa uagucucaug uuacggaaaa acaaaaugca cagcaaguaa uaaaaauaga     1260

ggaauaauaa aaacauucuc uaauggcugc gacuacguau ccaauaaagg cguugacaca     1320

guauccguag gcaacacacu cuacuauguu aacaaacaag aaggaaaaag uuuauacguu     1380

aaaggagaac caauuauaaa cuuuuacgac ccacucguau ucccaucuga ugaauuugac     1440

gcaucaaucu cacaaguaaa ugaaaaaauc aaucaguccc uugccuuuau aagaaaauca     1500

gaugaacuuu uacacaacgu uaacgccgga aaaucaacaa ccaauauaau gaucacaacc     1560

auaauaauag uuauaauugu aauuuuauua uccuuaauag ccgucggacu acuacuauac     1620

ugcaaagcaa gaucuacacc cguaacccua ucaaaagacc aacuaagugg aauaaauaac     1680

auugcauucu caaauuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3994
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  3994
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuaaa ggcaaacgca      120

aucacuacaa uucuaaccgc cgugacauuc ugcuucgccu ccggacaaaa caucaccgaa      180

gaauuuuacc aauccacaug cucggccguc aguaaaggcu accucucggc ucuccgaacc      240

ggcugguaca ccuccgucau caccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacucg acaaauacaa aaacgccguc      360

acagaacucc aacuacuaau gcaaucaaca cccgcuacag gaagcggcuc cgccaucgcc      420

agcggcguag cugucugcaa aguccuccac cucgaaggug aagucaacaa aaucaaauca      480

gcccuacuca gcacaaacaa agccguugua agccuaucca acggcgucuc cguacuaaca      540

uucaaagucc uugaccucaa gaacuacauc gacaaacaac uucucccaau ccuaaacaaa      600

caaagcugcu caauuuccaa caucgaaaca guaaucgaau uucaacaaaa aaacaaccga      660

cuccucgaaa ucacccgcga auuuuccguu aacgccggcg uuacaacccc cgucuccacc      720

uacaugcuca ccaauuccga acuacuauca cucauaaacg acaugccuau cacaaacgac      780

caaaaaaaac uaaugucaaa caauguccaa aucguccgcc agcaaagcua uuccaucaug      840

ugcaucauca aagaggaagu ccucgccuac guaguccaac ugccccucua cggcgucauu      900

gauacccccu gcuggaaacu ccacaccucc ccccucugca ccacaaacac caaagaaggu      960

uccaacaucu gccuaacacg aaccgacaga ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccuguaaa guccagucua accgcgucuu cugcgacaca     1080

augaacucaa gaacccuacc uuccgaagua aaccucugca acguagacau cuucaacccu     1140

aaauacgacu gcaaaaucau gacuucaaaa acagacguaa gcucuuccgu aaucacuucc     1200

cucggcgcca ucguauccug cuacgguaaa accaaaugca ccgccuccaa caaaaaccga     1260

gggaucauaa aaaccuucuc caacggcugc gacuacguau cuaacaaagg cgucgacacc     1320

gucuccgucg gcaacacccu cuauuacgua aacaaacaag agggcaaauc acuauacguc     1380

aaaggcgagc caaucauaaa cuucuaugac ccacucgucu ucccuucaga cgaauuugau     1440

gccagcauca gccaagucaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaagc     1500

gacgaacucc uucacaacgu caacgcaggc aaaucaacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu uauccuacuc agccucaucg caguuggucu ucuccuuuac     1620

ugcaaagccc gcuccacccc cgucacccuc aguaaagacc aacucagcgg aaucaacaac     1680

auagcauucu ccaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  3995
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3995
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3996
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  3996
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3997
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  3997
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3998
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  3998
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgcu uucucaaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  3999
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  3999
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4000
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4000
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4001
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4001
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaauac uaaaagccaa ugcaauaaca accauacuaa ccgccguaac auuuuguuuc      240

gcaucagguc aaaacauaac cgaagaauuu uaucaaucaa caugcucagc aguaucaaaa      300

ggauacuuau ccgcucuaag aacaggaugg uacacaagug uaauuacaau agagcucuca      360

aacauaaaag aaaacaaaug caauggaacu gacgcaaaag uuaaacuuau aaaacaagaa      420

cuagauaaau auaaaaaugc aguaaccgaa uuacaacucc uaaugcaauc cacaccugcu      480

accgguuccg gaucagccau agcaucugga guagccguau gcaaaguccu ccaccuagaa      540

ggagaaguaa auaaaaucaa aucagcacua uuaucuacca auaaagcagu ugucucacua      600

uccaauggcg uaucaguacu aacauucaaa guauuagacc uuaaaaacua cauagacaaa      660

caacuauuac caauucugaa caaacaaucc uguucaauau caaacaucga aacgguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaauaacaa gagaauuuuc aguaaaugca      780

ggaguuacaa cacccgucuc caccuacaug cucacaaauu cagaauuauu aucacuuaua      840

aacgacaugc caauaacuaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaauaguc      900

cgacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccuagc cuacguuguc      960

caacuacccu uauauggagu aauagauacc ccaugcugga aacuucauac cuccccccua     1020

ugcacaacaa acacaaaaga aggcucaaac aucugcuuaa cacguacaga ccgagguugg     1080

uacugugaua acgcaggauc cguaucauuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaaccgcg uuuuuuguga caccaugaac agcagaaccc ucccuucaga aguaaaccua     1200

ugcaacgucg auauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaaccgau     1260

gucucaucuu caguaauaac cucucuagga gcaauagucu cauguuacgg aaaaacaaaa     1320

ugcacagcaa guaauaaaaa uagaggaaua auaaaaacau ucucuaaugg cugcgacuac     1380

guauccaaua aaggcguuga cacaguaucc guaggcaaca cacucuacua uguuaacaaa     1440

caagaaggaa aaaguuuaua cguuaaagga gaaccaauua uaaacuuuua cgacccacuc     1500

guauucccau cugaugaauu ugacgcauca aucucacaag uaaaugaaaa aaucaaucag     1560

ucccuugccu uuauaagaaa aucagaugaa cuuuuacaca acguuaacgc cggaaaauca     1620

acaaccaaua uaaugaucac aaccauaaua auaguuauaa uuguaauuuu auuauccuua     1680

auagccgucg gacuacuacu auacugcaaa gcaagaucua cacccguaac ccuaucaaaa     1740

gaccaacuaa guggaauaaa uaacauugca uucucaaauu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4002
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4002
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uaaaggcaaa cgcaaucacu acaauucuaa ccgccgugac auucugcuuc      240

gccuccggac aaaacaucac cgaagaauuu uaccaaucca caugcucggc cgucaguaaa      300

ggcuaccucu cggcucuccg aaccggcugg uacaccuccg ucaucaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cucgacaaau acaaaaacgc cgucacagaa cuccaacuac uaaugcaauc aacacccgcu      480

acaggaagcg gcuccgccau cgccagcggc guagcugucu gcaaaguccu ccaccucgaa      540

ggugaaguca acaaaaucaa aucagcccua cucagcacaa acaaagccgu uguaagccua      600

uccaacggcg ucuccguacu aacauucaaa guccuugacc ucaagaacua caucgacaaa      660

caacuucucc caauccuaaa caaacaaagc ugcucaauuu ccaacaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ccgacuccuc gaaaucaccc gcgaauuuuc cguuaacgcc      780

ggcguuacaa cccccgucuc caccuacaug cucaccaauu ccgaacuacu aucacucaua      840

aacgacaugc cuaucacaaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaaucguc      900

cgccagcaaa gcuauuccau caugugcauc aucaaagagg aaguccucgc cuacguaguc      960

caacugcccc ucuacggcgu cauugauacc cccugcugga aacuccacac cuccccccuc     1020

ugcaccacaa acaccaaaga agguuccaac aucugccuaa cacgaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccaag cagaaaccug uaaaguccag     1140

ucuaaccgcg ucuucugcga cacaaugaac ucaagaaccc uaccuuccga aguaaaccuc     1200

ugcaacguag acaucuucaa cccuaaauac gacugcaaaa ucaugacuuc aaaaacagac     1260

guaagcucuu ccguaaucac uucccucggc gccaucguau ccugcuacgg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgagggauc auaaaaaccu ucuccaacgg cugcgacuac     1380

guaucuaaca aaggcgucga caccgucucc gucggcaaca cccucuauua cguaaacaaa     1440

caagagggca aaucacuaua cgucaaaggc gagccaauca uaaacuucua ugacccacuc     1500

gucuucccuu cagacgaauu ugaugccagc aucagccaag ucaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa aagcgacgaa cuccuucaca acgucaacgc aggcaaauca     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucguuauccu acucagccuc     1680

aucgcaguug gucuucuccu uuacugcaaa gcccgcucca cccccgucac ccucaguaaa     1740

gaccaacuca gcggaaucaa caacauagca uucuccaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4003
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4003
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4004
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4004
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4005
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4005
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4006
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4006
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcuuucucaa     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4007
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4007
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4008
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4008
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4009
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4009
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uacuaaaagc caaugcaaua acaaccauac      120

uaaccgccgu aacauuuugu uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau      180

caacaugcuc agcaguauca aaaggauacu uauccgcucu aagaacagga ugguacacaa      240

guguaauuac aauagagcuc ucaaacauaa aagaaaacaa augcaaugga acugacgcaa      300

aaguuaaacu uauaaaacaa gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac      360

uccuaaugca auccacaccu gcuaccgguu ccggaucagc cauagcaucu ggaguagccg      420

uaugcaaagu ccuccaccua gaaggagaag uaaauaaaau caaaucagca cuauuaucua      480

ccaauaaagc aguugucuca cuauccaaug gcguaucagu acuaacauuc aaaguauuag      540

accuuaaaaa cuacauagac aaacaacuau uaccaauucu gaacaaacaa uccuguucaa      600

uaucaaacau cgaaacggua auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa      660

caagagaauu uucaguaaau gcaggaguua caacacccgu cuccaccuac augcucacaa      720

auucagaauu auuaucacuu auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaaua guccgacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu agccuacguu guccaacuac ccuuauaugg aguaauagau accccaugcu      900

ggaaacuuca uaccuccccc cuaugcacaa caaacacaaa agaaggcuca aacaucugcu      960

uaacacguac agaccgaggu ugguacugug auaacgcagg auccguauca uuuuucccac     1020

aagcagaaac augcaaagua caaucaaacc gcguuuuuug ugacaccaug aacagcagaa     1080

cccucccuuc agaaguaaac cuaugcaacg ucgauauauu uaacccaaaa uacgauugca     1140

aaauaaugac aucaaaaacc gaugucucau cuucaguaau aaccucucua ggagcaauag     1200

ucucauguua cggaaaaaca aaaugcacag caaguaauaa aaauagagga auaauaaaaa     1260

cauucucuaa uggcugcgac uacguaucca auaaaggcgu ugacacagua uccguaggca     1320

acacacucua cuauguuaac aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa     1380

uuauaaacuu uuacgaccca cucguauucc caucugauga auuugacgca ucaaucucac     1440

aaguaaauga aaaaaucaau cagucccuug ccuuuauaag aaaaucagau gaacuuuuac     1500

acaacguuaa cgccggaaaa ucaacaacca auauaaugau cacaaccaua auaauaguua     1560

uaauuguaau uuuauuaucc uuaauagccg ucggacuacu acuauacugc aaagcaagau     1620

cuacacccgu aacccuauca aaagaccaac uaaguggaau aaauaacauu gcauucucaa     1680

auuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4010
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4010
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc      120

uaaccgccgu gacauucugc uucgccuccg gacaaaacau caccgaagaa uuuuaccaau      180

ccacaugcuc ggccgucagu aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu      240

ccgucaucac caucgaacuc uccaacauca aagaaaacaa augcaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacucgaca aauacaaaaa cgccgucaca gaacuccaac      360

uacuaaugca aucaacaccc gcuacaggaa gcggcuccgc caucgccagc ggcguagcug      420

ucugcaaagu ccuccaccuc gaaggugaag ucaacaaaau caaaucagcc cuacucagca      480

caaacaaagc cguuguaagc cuauccaacg gcgucuccgu acuaacauuc aaaguccuug      540

accucaagaa cuacaucgac aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa      600

uuuccaacau cgaaacagua aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca      660

cccgcgaauu uuccguuaac gccggcguua caacccccgu cuccaccuac augcucacca      720

auuccgaacu acuaucacuc auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaauc guccgccagc aaagcuauuc caucaugugc aucaucaaag      840

aggaaguccu cgccuacgua guccaacugc cccucuacgg cgucauugau acccccugcu      900

ggaaacucca caccuccccc cucugcacca caaacaccaa agaagguucc aacaucugcc      960

uaacacgaac cgacagaggc ugguacugcg acaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cuguaaaguc cagucuaacc gcgucuucug cgacacaaug aacucaagaa     1080

cccuaccuuc cgaaguaaac cucugcaacg uagacaucuu caacccuaaa uacgacugca     1140

aaaucaugac uucaaaaaca gacguaagcu cuuccguaau cacuucccuc ggcgccaucg     1200

uauccugcua cgguaaaacc aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa     1260

ccuucuccaa cggcugcgac uacguaucua acaaaggcgu cgacaccguc uccgucggca     1320

acacccucua uuacguaaac aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa     1380

ucauaaacuu cuaugaccca cucgucuucc cuucagacga auuugaugcc agcaucagcc     1440

aagucaacga aaaaaucaac caaucacucg ccuucauccg caaaagcgac gaacuccuuc     1500

acaacgucaa cgcaggcaaa ucaaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucguuau ccuacucagc cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu     1620

ccacccccgu cacccucagu aaagaccaac ucagcggaau caacaacaua gcauucucca     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4011
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4011
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4012
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4012
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4013
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4013
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4014
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4014
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgcu uucucaaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4015
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4015
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4016
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4016
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4017
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4017
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaauac uaaaagccaa ugcaauaaca accauacuaa ccgccguaac auuuuguuuc      240

gcaucagguc aaaacauaac cgaagaauuu uaucaaucaa caugcucagc aguaucaaaa      300

ggauacuuau ccgcucuaag aacaggaugg uacacaagug uaauuacaau agagcucuca      360

aacauaaaag aaaacaaaug caauggaacu gacgcaaaag uuaaacuuau aaaacaagaa      420

cuagauaaau auaaaaaugc aguaaccgaa uuacaacucc uaaugcaauc cacaccugcu      480

accgguuccg gaucagccau agcaucugga guagccguau gcaaaguccu ccaccuagaa      540

ggagaaguaa auaaaaucaa aucagcacua uuaucuacca auaaagcagu ugucucacua      600

uccaauggcg uaucaguacu aacauucaaa guauuagacc uuaaaaacua cauagacaaa      660

caacuauuac caauucugaa caaacaaucc uguucaauau caaacaucga aacgguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaauaacaa gagaauuuuc aguaaaugca      780

ggaguuacaa cacccgucuc caccuacaug cucacaaauu cagaauuauu aucacuuaua      840

aacgacaugc caauaacuaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaauaguc      900

cgacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccuagc cuacguuguc      960

caacuacccu uauauggagu aauagauacc ccaugcugga aacuucauac cuccccccua     1020

ugcacaacaa acacaaaaga aggcucaaac aucugcuuaa cacguacaga ccgagguugg     1080

uacugugaua acgcaggauc cguaucauuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaaccgcg uuuuuuguga caccaugaac agcagaaccc ucccuucaga aguaaaccua     1200

ugcaacgucg auauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaaccgau     1260

gucucaucuu caguaauaac cucucuagga gcaauagucu cauguuacgg aaaaacaaaa     1320

ugcacagcaa guaauaaaaa uagaggaaua auaaaaacau ucucuaaugg cugcgacuac     1380

guauccaaua aaggcguuga cacaguaucc guaggcaaca cacucuacua uguuaacaaa     1440

caagaaggaa aaaguuuaua cguuaaagga gaaccaauua uaaacuuuua cgacccacuc     1500

guauucccau cugaugaauu ugacgcauca aucucacaag uaaaugaaaa aaucaaucag     1560

ucccuugccu uuauaagaaa aucagaugaa cuuuuacaca acguuaacgc cggaaaauca     1620

acaaccaaua uaaugaucac aaccauaaua auaguuauaa uuguaauuuu auuauccuua     1680

auagccgucg gacuacuacu auacugcaaa gcaagaucua cacccguaac ccuaucaaaa     1740

gaccaacuaa guggaauaaa uaacauugca uucucaaauu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4018
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4018
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uaaaggcaaa cgcaaucacu acaauucuaa ccgccgugac auucugcuuc      240

gccuccggac aaaacaucac cgaagaauuu uaccaaucca caugcucggc cgucaguaaa      300

ggcuaccucu cggcucuccg aaccggcugg uacaccuccg ucaucaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cucgacaaau acaaaaacgc cgucacagaa cuccaacuac uaaugcaauc aacacccgcu      480

acaggaagcg gcuccgccau cgccagcggc guagcugucu gcaaaguccu ccaccucgaa      540

ggugaaguca acaaaaucaa aucagcccua cucagcacaa acaaagccgu uguaagccua      600

uccaacggcg ucuccguacu aacauucaaa guccuugacc ucaagaacua caucgacaaa      660

caacuucucc caauccuaaa caaacaaagc ugcucaauuu ccaacaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ccgacuccuc gaaaucaccc gcgaauuuuc cguuaacgcc      780

ggcguuacaa cccccgucuc caccuacaug cucaccaauu ccgaacuacu aucacucaua      840

aacgacaugc cuaucacaaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaaucguc      900

cgccagcaaa gcuauuccau caugugcauc aucaaagagg aaguccucgc cuacguaguc      960

caacugcccc ucuacggcgu cauugauacc cccugcugga aacuccacac cuccccccuc     1020

ugcaccacaa acaccaaaga agguuccaac aucugccuaa cacgaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccaag cagaaaccug uaaaguccag     1140

ucuaaccgcg ucuucugcga cacaaugaac ucaagaaccc uaccuuccga aguaaaccuc     1200

ugcaacguag acaucuucaa cccuaaauac gacugcaaaa ucaugacuuc aaaaacagac     1260

guaagcucuu ccguaaucac uucccucggc gccaucguau ccugcuacgg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgagggauc auaaaaaccu ucuccaacgg cugcgacuac     1380

guaucuaaca aaggcgucga caccgucucc gucggcaaca cccucuauua cguaaacaaa     1440

caagagggca aaucacuaua cgucaaaggc gagccaauca uaaacuucua ugacccacuc     1500

gucuucccuu cagacgaauu ugaugccagc aucagccaag ucaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa aagcgacgaa cuccuucaca acgucaacgc aggcaaauca     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucguuauccu acucagccuc     1680

aucgcaguug gucuucuccu uuacugcaaa gcccgcucca cccccgucac ccucaguaaa     1740

gaccaacuca gcggaaucaa caacauagca uucuccaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4019
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4019
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4020
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4020
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      480

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      540

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1020

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1140

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1260

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1320

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1380

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1680

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4021
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4021
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4022
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4022
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      480

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      540

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      600

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      720

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      780

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      840

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua      900

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca      960

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc     1020

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1080

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1140

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1200

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1260

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1320

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1380

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1440

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1500

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1560

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1620

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1680

aaggaccagc ucuccggcau aaacaauauc gcuuucucaa acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4023
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4023
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4024
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4024
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      480

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      540

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      600

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      720

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      780

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      840

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug      900

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu      960

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga     1020

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1080

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1140

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1200

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1260

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1320

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1380

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1440

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1500

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1620

cugaucgccg ugggccuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1680

aaggaccagc ucucugggau uaacaauauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4025
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4025
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuaa uacuaaaagc caaugcaaua acaaccauac uaaccgccgu aacauuuugu      180

uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau caacaugcuc agcaguauca      240

aaaggauacu uauccgcucu aagaacagga ugguacacaa guguaauuac aauagagcuc      300

ucaaacauaa aagaaaacaa augcaaugga acugacgcaa aaguuaaacu uauaaaacaa      360

gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac uccuaaugca auccacaccu      420

gcuaccgguu ccggaucagc cauagcaucu ggaguagccg uaugcaaagu ccuccaccua      480

gaaggagaag uaaauaaaau caaaucagca cuauuaucua ccaauaaagc aguugucuca      540

cuauccaaug gcguaucagu acuaacauuc aaaguauuag accuuaaaaa cuacauagac      600

aaacaacuau uaccaauucu gaacaaacaa uccuguucaa uaucaaacau cgaaacggua      660

auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa caagagaauu uucaguaaau      720

gcaggaguua caacacccgu cuccaccuac augcucacaa auucagaauu auuaucacuu      780

auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa ugucaaacaa uguccaaaua      840

guccgacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu agccuacguu      900

guccaacuac ccuuauaugg aguaauagau accccaugcu ggaaacuuca uaccuccccc      960

cuaugcacaa caaacacaaa agaaggcuca aacaucugcu uaacacguac agaccgaggu     1020

ugguacugug auaacgcagg auccguauca uuuuucccac aagcagaaac augcaaagua     1080

caaucaaacc gcguuuuuug ugacaccaug aacagcagaa cccucccuuc agaaguaaac     1140

cuaugcaacg ucgauauauu uaacccaaaa uacgauugca aaauaaugac aucaaaaacc     1200

gaugucucau cuucaguaau aaccucucua ggagcaauag ucucauguua cggaaaaaca     1260

aaaugcacag caaguaauaa aaauagagga auaauaaaaa cauucucuaa uggcugcgac     1320

uacguaucca auaaaggcgu ugacacagua uccguaggca acacacucua cuauguuaac     1380

aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa uuauaaacuu uuacgaccca     1440

cucguauucc caucugauga auuugacgca ucaaucucac aaguaaauga aaaaaucaau     1500

cagucccuug ccuuuauaag aaaaucagau gaacuuuuac acaacguuaa cgccggaaaa     1560

ucaacaacca auauaaugau cacaaccaua auaauaguua uaauuguaau uuuauuaucc     1620

uuaauagccg ucggacuacu acuauacugc aaagcaagau cuacacccgu aacccuauca     1680

aaagaccaac uaaguggaau aaauaacauu gcauucucaa auuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4026
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4026
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc uaaccgccgu gacauucugc      180

uucgccuccg gacaaaacau caccgaagaa uuuuaccaau ccacaugcuc ggccgucagu      240

aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu ccgucaucac caucgaacuc      300

uccaacauca aagaaaacaa augcaacggc accgacgcca aagucaaacu aaucaaacaa      360

gaacucgaca aauacaaaaa cgccgucaca gaacuccaac uacuaaugca aucaacaccc      420

gcuacaggaa gcggcuccgc caucgccagc ggcguagcug ucugcaaagu ccuccaccuc      480

gaaggugaag ucaacaaaau caaaucagcc cuacucagca caaacaaagc cguuguaagc      540

cuauccaacg gcgucuccgu acuaacauuc aaaguccuug accucaagaa cuacaucgac      600

aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa uuuccaacau cgaaacagua      660

aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca cccgcgaauu uuccguuaac      720

gccggcguua caacccccgu cuccaccuac augcucacca auuccgaacu acuaucacuc      780

auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa ugucaaacaa uguccaaauc      840

guccgccagc aaagcuauuc caucaugugc aucaucaaag aggaaguccu cgccuacgua      900

guccaacugc cccucuacgg cgucauugau acccccugcu ggaaacucca caccuccccc      960

cucugcacca caaacaccaa agaagguucc aacaucugcc uaacacgaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuuccccc aagcagaaac cuguaaaguc     1080

cagucuaacc gcgucuucug cgacacaaug aacucaagaa cccuaccuuc cgaaguaaac     1140

cucugcaacg uagacaucuu caacccuaaa uacgacugca aaaucaugac uucaaaaaca     1200

gacguaagcu cuuccguaau cacuucccuc ggcgccaucg uauccugcua cgguaaaacc     1260

aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa ccuucuccaa cggcugcgac     1320

uacguaucua acaaaggcgu cgacaccguc uccgucggca acacccucua uuacguaaac     1380

aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa ucauaaacuu cuaugaccca     1440

cucgucuucc cuucagacga auuugaugcc agcaucagcc aagucaacga aaaaaucaac     1500

caaucacucg ccuucauccg caaaagcgac gaacuccuuc acaacgucaa cgcaggcaaa     1560

ucaaccacca acaucaugau caccaccauc aucaucguca ucaucguuau ccuacucagc     1620

cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu ccacccccgu cacccucagu     1680

aaagaccaac ucagcggaau caacaacaua gcauucucca acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4027
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4027
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4028
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4028
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4029
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4029
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4030
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4030
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcuuucuc aaacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4031
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4031
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4032
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4032
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4033
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4033
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauacuaaaa      120

gccaaugcaa uaacaaccau acuaaccgcc guaacauuuu guuucgcauc aggucaaaac      180

auaaccgaag aauuuuauca aucaacaugc ucagcaguau caaaaggaua cuuauccgcu      240

cuaagaacag gaugguacac aaguguaauu acaauagagc ucucaaacau aaaagaaaac      300

aaaugcaaug gaacugacgc aaaaguuaaa cuuauaaaac aagaacuaga uaaauauaaa      360

aaugcaguaa ccgaauuaca acuccuaaug caauccacac cugcuaccgg uuccggauca      420

gccauagcau cuggaguagc cguaugcaaa guccuccacc uagaaggaga aguaaauaaa      480

aucaaaucag cacuauuauc uaccaauaaa gcaguugucu cacuauccaa uggcguauca      540

guacuaacau ucaaaguauu agaccuuaaa aacuacauag acaaacaacu auuaccaauu      600

cugaacaaac aauccuguuc aauaucaaac aucgaaacgg uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau aacaagagaa uuuucaguaa augcaggagu uacaacaccc      720

gucuccaccu acaugcucac aaauucagaa uuauuaucac uuauaaacga caugccaaua      780

acuaacgacc aaaaaaaacu aaugucaaac aauguccaaa uaguccgaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cuagccuacg uuguccaacu acccuuauau      900

ggaguaauag auaccccaug cuggaaacuu cauaccuccc cccuaugcac aacaaacaca      960

aaagaaggcu caaacaucug cuuaacacgu acagaccgag guugguacug ugauaacgca     1020

ggauccguau cauuuuuccc acaagcagaa acaugcaaag uacaaucaaa ccgcguuuuu     1080

ugugacacca ugaacagcag aacccucccu ucagaaguaa accuaugcaa cgucgauaua     1140

uuuaacccaa aauacgauug caaaauaaug acaucaaaaa ccgaugucuc aucuucagua     1200

auaaccucuc uaggagcaau agucucaugu uacggaaaaa caaaaugcac agcaaguaau     1260

aaaaauagag gaauaauaaa aacauucucu aauggcugcg acuacguauc caauaaaggc     1320

guugacacag uauccguagg caacacacuc uacuauguua acaaacaaga aggaaaaagu     1380

uuauacguua aaggagaacc aauuauaaac uuuuacgacc cacucguauu cccaucugau     1440

gaauuugacg caucaaucuc acaaguaaau gaaaaaauca aucagucccu ugccuuuaua     1500

agaaaaucag augaacuuuu acacaacguu aacgccggaa aaucaacaac caauauaaug     1560

aucacaacca uaauaauagu uauaauugua auuuuauuau ccuuaauagc cgucggacua     1620

cuacuauacu gcaaagcaag aucuacaccc guaacccuau caaaagacca acuaagugga     1680

auaaauaaca uugcauucuc aaauuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4034
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4034
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuaaag      120

gcaaacgcaa ucacuacaau ucuaaccgcc gugacauucu gcuucgccuc cggacaaaac      180

aucaccgaag aauuuuacca auccacaugc ucggccguca guaaaggcua ccucucggcu      240

cuccgaaccg gcugguacac cuccgucauc accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacucga caaauacaaa      360

aacgccguca cagaacucca acuacuaaug caaucaacac ccgcuacagg aagcggcucc      420

gccaucgcca gcggcguagc ugucugcaaa guccuccacc ucgaagguga agucaacaaa      480

aucaaaucag cccuacucag cacaaacaaa gccguuguaa gccuauccaa cggcgucucc      540

guacuaacau ucaaaguccu ugaccucaag aacuacaucg acaaacaacu ucucccaauc      600

cuaaacaaac aaagcugcuc aauuuccaac aucgaaacag uaaucgaauu ucaacaaaaa      660

aacaaccgac uccucgaaau cacccgcgaa uuuuccguua acgccggcgu uacaaccccc      720

gucuccaccu acaugcucac caauuccgaa cuacuaucac ucauaaacga caugccuauc      780

acaaacgacc aaaaaaaacu aaugucaaac aauguccaaa ucguccgcca gcaaagcuau      840

uccaucaugu gcaucaucaa agaggaaguc cucgccuacg uaguccaacu gccccucuac      900

ggcgucauug auacccccug cuggaaacuc cacaccuccc cccucugcac cacaaacacc      960

aaagaagguu ccaacaucug ccuaacacga accgacagag gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accuguaaag uccagucuaa ccgcgucuuc     1080

ugcgacacaa ugaacucaag aacccuaccu uccgaaguaa accucugcaa cguagacauc     1140

uucaacccua aauacgacug caaaaucaug acuucaaaaa cagacguaag cucuuccgua     1200

aucacuuccc ucggcgccau cguauccugc uacgguaaaa ccaaaugcac cgccuccaac     1260

aaaaaccgag ggaucauaaa aaccuucucc aacggcugcg acuacguauc uaacaaaggc     1320

gucgacaccg ucuccgucgg caacacccuc uauuacguaa acaaacaaga gggcaaauca     1380

cuauacguca aaggcgagcc aaucauaaac uucuaugacc cacucgucuu cccuucagac     1440

gaauuugaug ccagcaucag ccaagucaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaaagcg acgaacuccu ucacaacguc aacgcaggca aaucaaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguu auccuacuca gccucaucgc aguuggucuu     1620

cuccuuuacu gcaaagcccg cuccaccccc gucacccuca guaaagacca acucagcgga     1680

aucaacaaca uagcauucuc caacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4035
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4035
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4036
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4036
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4037
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4037
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4038
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4038
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcuuucuc aaacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4039
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4039
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4040
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4040
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4041
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4041
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauacuaaaa gccaaugcaa uaacaaccau acuaaccgcc      120

guaacauuuu guuucgcauc aggucaaaac auaaccgaag aauuuuauca aucaacaugc      180

ucagcaguau caaaaggaua cuuauccgcu cuaagaacag gaugguacac aaguguaauu      240

acaauagagc ucucaaacau aaaagaaaac aaaugcaaug gaacugacgc aaaaguuaaa      300

cuuauaaaac aagaacuaga uaaauauaaa aaugcaguaa ccgaauuaca acuccuaaug      360

caauccacac cugcuaccgg uuccggauca gccauagcau cuggaguagc cguaugcaaa      420

guccuccacc uagaaggaga aguaaauaaa aucaaaucag cacuauuauc uaccaauaaa      480

gcaguugucu cacuauccaa uggcguauca guacuaacau ucaaaguauu agaccuuaaa      540

aacuacauag acaaacaacu auuaccaauu cugaacaaac aauccuguuc aauaucaaac      600

aucgaaacgg uaauagaauu ucaacaaaaa aauaacagau uacuugaaau aacaagagaa      660

uuuucaguaa augcaggagu uacaacaccc gucuccaccu acaugcucac aaauucagaa      720

uuauuaucac uuauaaacga caugccaaua acuaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa uaguccgaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cuagccuacg uuguccaacu acccuuauau ggaguaauag auaccccaug cuggaaacuu      900

cauaccuccc cccuaugcac aacaaacaca aaagaaggcu caaacaucug cuuaacacgu      960

acagaccgag guugguacug ugauaacgca ggauccguau cauuuuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa ccgcguuuuu ugugacacca ugaacagcag aacccucccu     1080

ucagaaguaa accuaugcaa cgucgauaua uuuaacccaa aauacgauug caaaauaaug     1140

acaucaaaaa ccgaugucuc aucuucagua auaaccucuc uaggagcaau agucucaugu     1200

uacggaaaaa caaaaugcac agcaaguaau aaaaauagag gaauaauaaa aacauucucu     1260

aauggcugcg acuacguauc caauaaaggc guugacacag uauccguagg caacacacuc     1320

uacuauguua acaaacaaga aggaaaaagu uuauacguua aaggagaacc aauuauaaac     1380

uuuuacgacc cacucguauu cccaucugau gaauuugacg caucaaucuc acaaguaaau     1440

gaaaaaauca aucagucccu ugccuuuaua agaaaaucag augaacuuuu acacaacguu     1500

aacgccggaa aaucaacaac caauauaaug aucacaacca uaauaauagu uauaauugua     1560

auuuuauuau ccuuaauagc cgucggacua cuacuauacu gcaaagcaag aucuacaccc     1620

guaacccuau caaaagacca acuaagugga auaaauaaca uugcauucuc aaauuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4042
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4042
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuaaag gcaaacgcaa ucacuacaau ucuaaccgcc      120

gugacauucu gcuucgccuc cggacaaaac aucaccgaag aauuuuacca auccacaugc      180

ucggccguca guaaaggcua ccucucggcu cuccgaaccg gcugguacac cuccgucauc      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacucga caaauacaaa aacgccguca cagaacucca acuacuaaug      360

caaucaacac ccgcuacagg aagcggcucc gccaucgcca gcggcguagc ugucugcaaa      420

guccuccacc ucgaagguga agucaacaaa aucaaaucag cccuacucag cacaaacaaa      480

gccguuguaa gccuauccaa cggcgucucc guacuaacau ucaaaguccu ugaccucaag      540

aacuacaucg acaaacaacu ucucccaauc cuaaacaaac aaagcugcuc aauuuccaac      600

aucgaaacag uaaucgaauu ucaacaaaaa aacaaccgac uccucgaaau cacccgcgaa      660

uuuuccguua acgccggcgu uacaaccccc gucuccaccu acaugcucac caauuccgaa      720

cuacuaucac ucauaaacga caugccuauc acaaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa ucguccgcca gcaaagcuau uccaucaugu gcaucaucaa agaggaaguc      840

cucgccuacg uaguccaacu gccccucuac ggcgucauug auacccccug cuggaaacuc      900

cacaccuccc cccucugcac cacaaacacc aaagaagguu ccaacaucug ccuaacacga      960

accgacagag gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accuguaaag uccagucuaa ccgcgucuuc ugcgacacaa ugaacucaag aacccuaccu     1080

uccgaaguaa accucugcaa cguagacauc uucaacccua aauacgacug caaaaucaug     1140

acuucaaaaa cagacguaag cucuuccgua aucacuuccc ucggcgccau cguauccugc     1200

uacgguaaaa ccaaaugcac cgccuccaac aaaaaccgag ggaucauaaa aaccuucucc     1260

aacggcugcg acuacguauc uaacaaaggc gucgacaccg ucuccgucgg caacacccuc     1320

uauuacguaa acaaacaaga gggcaaauca cuauacguca aaggcgagcc aaucauaaac     1380

uucuaugacc cacucgucuu cccuucagac gaauuugaug ccagcaucag ccaagucaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaaagcg acgaacuccu ucacaacguc     1500

aacgcaggca aaucaaccac caacaucaug aucaccacca ucaucaucgu caucaucguu     1560

auccuacuca gccucaucgc aguuggucuu cuccuuuacu gcaaagcccg cuccaccccc     1620

gucacccuca guaaagacca acucagcgga aucaacaaca uagcauucuc caacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4043
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4043
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4044
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4044
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4045
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4045
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4046
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4046
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcuu ucucaaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4047
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4047
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4048
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4048
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4049
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4049
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauacu aaaagccaau gcaauaacaa ccauacuaac cgccguaaca      180

uuuuguuucg caucagguca aaacauaacc gaagaauuuu aucaaucaac augcucagca      240

guaucaaaag gauacuuauc cgcucuaaga acaggauggu acacaagugu aauuacaaua      300

gagcucucaa acauaaaaga aaacaaaugc aauggaacug acgcaaaagu uaaacuuaua      360

aaacaagaac uagauaaaua uaaaaaugca guaaccgaau uacaacuccu aaugcaaucc      420

acaccugcua ccgguuccgg aucagccaua gcaucuggag uagccguaug caaaguccuc      480

caccuagaag gagaaguaaa uaaaaucaaa ucagcacuau uaucuaccaa uaaagcaguu      540

gucucacuau ccaauggcgu aucaguacua acauucaaag uauuagaccu uaaaaacuac      600

auagacaaac aacuauuacc aauucugaac aaacaauccu guucaauauc aaacaucgaa      660

acgguaauag aauuucaaca aaaaaauaac agauuacuug aaauaacaag agaauuuuca      720

guaaaugcag gaguuacaac acccgucucc accuacaugc ucacaaauuc agaauuauua      780

ucacuuauaa acgacaugcc aauaacuaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaauagucc gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccuagcc      900

uacguugucc aacuacccuu auauggagua auagauaccc caugcuggaa acuucauacc      960

uccccccuau gcacaacaaa cacaaaagaa ggcucaaaca ucugcuuaac acguacagac     1020

cgagguuggu acugugauaa cgcaggaucc guaucauuuu ucccacaagc agaaacaugc     1080

aaaguacaau caaaccgcgu uuuuugugac accaugaaca gcagaacccu cccuucagaa     1140

guaaaccuau gcaacgucga uauauuuaac ccaaaauacg auugcaaaau aaugacauca     1200

aaaaccgaug ucucaucuuc aguaauaacc ucucuaggag caauagucuc auguuacgga     1260

aaaacaaaau gcacagcaag uaauaaaaau agaggaauaa uaaaaacauu cucuaauggc     1320

ugcgacuacg uauccaauaa aggcguugac acaguauccg uaggcaacac acucuacuau     1380

guuaacaaac aagaaggaaa aaguuuauac guuaaaggag aaccaauuau aaacuuuuac     1440

gacccacucg uauucccauc ugaugaauuu gacgcaucaa ucucacaagu aaaugaaaaa     1500

aucaaucagu cccuugccuu uauaagaaaa ucagaugaac uuuuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaauau aaugaucaca accauaauaa uaguuauaau uguaauuuua     1620

uuauccuuaa uagccgucgg acuacuacua uacugcaaag caagaucuac acccguaacc     1680

cuaucaaaag accaacuaag uggaauaaau aacauugcau ucucaaauua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4050
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4050
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu aaaggcaaac gcaaucacua caauucuaac cgccgugaca      180

uucugcuucg ccuccggaca aaacaucacc gaagaauuuu accaauccac augcucggcc      240

gucaguaaag gcuaccucuc ggcucuccga accggcuggu acaccuccgu caucaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagaac uccaacuacu aaugcaauca      420

acacccgcua caggaagcgg cuccgccauc gccagcggcg uagcugucug caaaguccuc      480

caccucgaag gugaagucaa caaaaucaaa ucagcccuac ucagcacaaa caaagccguu      540

guaagccuau ccaacggcgu cuccguacua acauucaaag uccuugaccu caagaacuac      600

aucgacaaac aacuucuccc aauccuaaac aaacaaagcu gcucaauuuc caacaucgaa      660

acaguaaucg aauuucaaca aaaaaacaac cgacuccucg aaaucacccg cgaauuuucc      720

guuaacgccg gcguuacaac ccccgucucc accuacaugc ucaccaauuc cgaacuacua      780

ucacucauaa acgacaugcc uaucacaaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaaucgucc gccagcaaag cuauuccauc augugcauca ucaaagagga aguccucgcc      900

uacguagucc aacugccccu cuacggcguc auugauaccc ccugcuggaa acuccacacc      960

uccccccucu gcaccacaaa caccaaagaa gguuccaaca ucugccuaac acgaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gucuccuucu ucccccaagc agaaaccugu     1080

aaaguccagu cuaaccgcgu cuucugcgac acaaugaacu caagaacccu accuuccgaa     1140

guaaaccucu gcaacguaga caucuucaac ccuaaauacg acugcaaaau caugacuuca     1200

aaaacagacg uaagcucuuc cguaaucacu ucccucggcg ccaucguauc cugcuacggu     1260

aaaaccaaau gcaccgccuc caacaaaaac cgagggauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg uaucuaacaa aggcgucgac accgucuccg ucggcaacac ccucuauuac     1380

guaaacaaac aagagggcaa aucacuauac gucaaaggcg agccaaucau aaacuucuau     1440

gacccacucg ucuucccuuc agacgaauuu gaugccagca ucagccaagu caacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa agcgacgaac uccuucacaa cgucaacgca     1560

ggcaaaucaa ccaccaacau caugaucacc accaucauca ucgucaucau cguuauccua     1620

cucagccuca ucgcaguugg ucuucuccuu uacugcaaag cccgcuccac ccccgucacc     1680

cucaguaaag accaacucag cggaaucaac aacauagcau ucuccaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4051
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4051
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4052
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4052
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4053
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4053
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4054
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4054
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcuuucu caaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4055
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4055
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4056
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4056
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4057
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4057
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauacuaaa agccaaugca      120

auaacaacca uacuaaccgc cguaacauuu uguuucgcau caggucaaaa cauaaccgaa      180

gaauuuuauc aaucaacaug cucagcagua ucaaaaggau acuuauccgc ucuaagaaca      240

ggaugguaca caaguguaau uacaauagag cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacugacg caaaaguuaa acuuauaaaa caagaacuag auaaauauaa aaaugcagua      360

accgaauuac aacuccuaau gcaauccaca ccugcuaccg guuccggauc agccauagca      420

ucuggaguag ccguaugcaa aguccuccac cuagaaggag aaguaaauaa aaucaaauca      480

gcacuauuau cuaccaauaa agcaguuguc ucacuaucca auggcguauc aguacuaaca      540

uucaaaguau uagaccuuaa aaacuacaua gacaaacaac uauuaccaau ucugaacaaa      600

caauccuguu caauaucaaa caucgaaacg guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa uaacaagaga auuuucagua aaugcaggag uuacaacacc cgucuccacc      720

uacaugcuca caaauucaga auuauuauca cuuauaaacg acaugccaau aacuaacgac      780

caaaaaaaac uaaugucaaa caauguccaa auaguccgac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccuagccuac guuguccaac uacccuuaua uggaguaaua      900

gauaccccau gcuggaaacu ucauaccucc ccccuaugca caacaaacac aaaagaaggc      960

ucaaacaucu gcuuaacacg uacagaccga gguugguacu gugauaacgc aggauccgua     1020

ucauuuuucc cacaagcaga aacaugcaaa guacaaucaa accgcguuuu uugugacacc     1080

augaacagca gaacccuccc uucagaagua aaccuaugca acgucgauau auuuaaccca     1140

aaauacgauu gcaaaauaau gacaucaaaa accgaugucu caucuucagu aauaaccucu     1200

cuaggagcaa uagucucaug uuacggaaaa acaaaaugca cagcaaguaa uaaaaauaga     1260

ggaauaauaa aaacauucuc uaauggcugc gacuacguau ccaauaaagg cguugacaca     1320

guauccguag gcaacacacu cuacuauguu aacaaacaag aaggaaaaag uuuauacguu     1380

aaaggagaac caauuauaaa cuuuuacgac ccacucguau ucccaucuga ugaauuugac     1440

gcaucaaucu cacaaguaaa ugaaaaaauc aaucaguccc uugccuuuau aagaaaauca     1500

gaugaacuuu uacacaacgu uaacgccgga aaaucaacaa ccaauauaau gaucacaacc     1560

auaauaauag uuauaauugu aauuuuauua uccuuaauag ccgucggacu acuacuauac     1620

ugcaaagcaa gaucuacacc cguaacccua ucaaaagacc aacuaagugg aauaaauaac     1680

auugcauucu caaauuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4058
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4058
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuaaa ggcaaacgca      120

aucacuacaa uucuaaccgc cgugacauuc ugcuucgccu ccggacaaaa caucaccgaa      180

gaauuuuacc aauccacaug cucggccguc aguaaaggcu accucucggc ucuccgaacc      240

ggcugguaca ccuccgucau caccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacucg acaaauacaa aaacgccguc      360

acagaacucc aacuacuaau gcaaucaaca cccgcuacag gaagcggcuc cgccaucgcc      420

agcggcguag cugucugcaa aguccuccac cucgaaggug aagucaacaa aaucaaauca      480

gcccuacuca gcacaaacaa agccguugua agccuaucca acggcgucuc cguacuaaca      540

uucaaagucc uugaccucaa gaacuacauc gacaaacaac uucucccaau ccuaaacaaa      600

caaagcugcu caauuuccaa caucgaaaca guaaucgaau uucaacaaaa aaacaaccga      660

cuccucgaaa ucacccgcga auuuuccguu aacgccggcg uuacaacccc cgucuccacc      720

uacaugcuca ccaauuccga acuacuauca cucauaaacg acaugccuau cacaaacgac      780

caaaaaaaac uaaugucaaa caauguccaa aucguccgcc agcaaagcua uuccaucaug      840

ugcaucauca aagaggaagu ccucgccuac guaguccaac ugccccucua cggcgucauu      900

gauacccccu gcuggaaacu ccacaccucc ccccucugca ccacaaacac caaagaaggu      960

uccaacaucu gccuaacacg aaccgacaga ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccuguaaa guccagucua accgcgucuu cugcgacaca     1080

augaacucaa gaacccuacc uuccgaagua aaccucugca acguagacau cuucaacccu     1140

aaauacgacu gcaaaaucau gacuucaaaa acagacguaa gcucuuccgu aaucacuucc     1200

cucggcgcca ucguauccug cuacgguaaa accaaaugca ccgccuccaa caaaaaccga     1260

gggaucauaa aaaccuucuc caacggcugc gacuacguau cuaacaaagg cgucgacacc     1320

gucuccgucg gcaacacccu cuauuacgua aacaaacaag agggcaaauc acuauacguc     1380

aaaggcgagc caaucauaaa cuucuaugac ccacucgucu ucccuucaga cgaauuugau     1440

gccagcauca gccaagucaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaagc     1500

gacgaacucc uucacaacgu caacgcaggc aaaucaacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu uauccuacuc agccucaucg caguuggucu ucuccuuuac     1620

ugcaaagccc gcuccacccc cgucacccuc aguaaagacc aacucagcgg aaucaacaac     1680

auagcauucu ccaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4059
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4059
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4060
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4060
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4061
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4061
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4062
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4062
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcuuucu caaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4063
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4063
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4064
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4064
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4065
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4065
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauacuaaa agccaaugca      120

auaacaacca uacuaaccgc cguaacauuu uguuucgcau caggucaaaa cauaaccgaa      180

gaauuuuauc aaucaacaug cucagcagua ucaaaaggau acuuauccgc ucuaagaaca      240

ggaugguaca caaguguaau uacaauagag cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacugacg caaaaguuaa acuuauaaaa caagaacuag auaaauauaa aaaugcagua      360

accgaauuac aacuccuaau gcaauccaca ccugcuaccg guuccggauc agccauagca      420

ucuggaguag ccguaugcaa aguccuccac cuagaaggag aaguaaauaa aaucaaauca      480

gcacuauuau cuaccaauaa agcaguuguc ucacuaucca auggcguauc aguacuaaca      540

uucaaaguau uagaccuuaa aaacuacaua gacaaacaac uauuaccaau ucugaacaaa      600

caauccuguu caauaucaaa caucgaaacg guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa uaacaagaga auuuucagua aaugcaggag uuacaacacc cgucuccacc      720

uacaugcuca caaauucaga auuauuauca cuuauaaacg acaugccaau aacuaacgac      780

caaaaaaaac uaaugucaaa caauguccaa auaguccgac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccuagccuac guuguccaac uacccuuaua uggaguaaua      900

gauaccccau gcuggaaacu ucauaccucc ccccuaugca caacaaacac aaaagaaggc      960

ucaaacaucu gcuuaacacg uacagaccga gguugguacu gugauaacgc aggauccgua     1020

ucauuuuucc cacaagcaga aacaugcaaa guacaaucaa accgcguuuu uugugacacc     1080

augaacagca gaacccuccc uucagaagua aaccuaugca acgucgauau auuuaaccca     1140

aaauacgauu gcaaaauaau gacaucaaaa accgaugucu caucuucagu aauaaccucu     1200

cuaggagcaa uagucucaug uuacggaaaa acaaaaugca cagcaaguaa uaaaaauaga     1260

ggaauaauaa aaacauucuc uaauggcugc gacuacguau ccaauaaagg cguugacaca     1320

guauccguag gcaacacacu cuacuauguu aacaaacaag aaggaaaaag uuuauacguu     1380

aaaggagaac caauuauaaa cuuuuacgac ccacucguau ucccaucuga ugaauuugac     1440

gcaucaaucu cacaaguaaa ugaaaaaauc aaucaguccc uugccuuuau aagaaaauca     1500

gaugaacuuu uacacaacgu uaacgccgga aaaucaacaa ccaauauaau gaucacaacc     1560

auaauaauag uuauaauugu aauuuuauua uccuuaauag ccgucggacu acuacuauac     1620

ugcaaagcaa gaucuacacc cguaacccua ucaaaagacc aacuaagugg aauaaauaac     1680

auugcauucu caaauuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4066
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4066
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuaaa ggcaaacgca      120

aucacuacaa uucuaaccgc cgugacauuc ugcuucgccu ccggacaaaa caucaccgaa      180

gaauuuuacc aauccacaug cucggccguc aguaaaggcu accucucggc ucuccgaacc      240

ggcugguaca ccuccgucau caccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacucg acaaauacaa aaacgccguc      360

acagaacucc aacuacuaau gcaaucaaca cccgcuacag gaagcggcuc cgccaucgcc      420

agcggcguag cugucugcaa aguccuccac cucgaaggug aagucaacaa aaucaaauca      480

gcccuacuca gcacaaacaa agccguugua agccuaucca acggcgucuc cguacuaaca      540

uucaaagucc uugaccucaa gaacuacauc gacaaacaac uucucccaau ccuaaacaaa      600

caaagcugcu caauuuccaa caucgaaaca guaaucgaau uucaacaaaa aaacaaccga      660

cuccucgaaa ucacccgcga auuuuccguu aacgccggcg uuacaacccc cgucuccacc      720

uacaugcuca ccaauuccga acuacuauca cucauaaacg acaugccuau cacaaacgac      780

caaaaaaaac uaaugucaaa caauguccaa aucguccgcc agcaaagcua uuccaucaug      840

ugcaucauca aagaggaagu ccucgccuac guaguccaac ugccccucua cggcgucauu      900

gauacccccu gcuggaaacu ccacaccucc ccccucugca ccacaaacac caaagaaggu      960

uccaacaucu gccuaacacg aaccgacaga ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccuguaaa guccagucua accgcgucuu cugcgacaca     1080

augaacucaa gaacccuacc uuccgaagua aaccucugca acguagacau cuucaacccu     1140

aaauacgacu gcaaaaucau gacuucaaaa acagacguaa gcucuuccgu aaucacuucc     1200

cucggcgcca ucguauccug cuacgguaaa accaaaugca ccgccuccaa caaaaaccga     1260

gggaucauaa aaaccuucuc caacggcugc gacuacguau cuaacaaagg cgucgacacc     1320

gucuccgucg gcaacacccu cuauuacgua aacaaacaag agggcaaauc acuauacguc     1380

aaaggcgagc caaucauaaa cuucuaugac ccacucgucu ucccuucaga cgaauuugau     1440

gccagcauca gccaagucaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaagc     1500

gacgaacucc uucacaacgu caacgcaggc aaaucaacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu uauccuacuc agccucaucg caguuggucu ucuccuuuac     1620

ugcaaagccc gcuccacccc cgucacccuc aguaaagacc aacucagcgg aaucaacaac     1680

auagcauucu ccaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4067
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4067
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4068
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4068
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4069
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4069
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4070
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4070
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcuuucu caaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4071
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4071
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4072
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4072
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4073
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4073
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauacuaaa agccaaugca      120

auaacaacca uacuaaccgc cguaacauuu uguuucgcau caggucaaaa cauaaccgaa      180

gaauuuuauc aaucaacaug cucagcagua ucaaaaggau acuuauccgc ucuaagaaca      240

ggaugguaca caaguguaau uacaauagag cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacugacg caaaaguuaa acuuauaaaa caagaacuag auaaauauaa aaaugcagua      360

accgaauuac aacuccuaau gcaauccaca ccugcuaccg guuccggauc agccauagca      420

ucuggaguag ccguaugcaa aguccuccac cuagaaggag aaguaaauaa aaucaaauca      480

gcacuauuau cuaccaauaa agcaguuguc ucacuaucca auggcguauc aguacuaaca      540

uucaaaguau uagaccuuaa aaacuacaua gacaaacaac uauuaccaau ucugaacaaa      600

caauccuguu caauaucaaa caucgaaacg guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa uaacaagaga auuuucagua aaugcaggag uuacaacacc cgucuccacc      720

uacaugcuca caaauucaga auuauuauca cuuauaaacg acaugccaau aacuaacgac      780

caaaaaaaac uaaugucaaa caauguccaa auaguccgac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccuagccuac guuguccaac uacccuuaua uggaguaaua      900

gauaccccau gcuggaaacu ucauaccucc ccccuaugca caacaaacac aaaagaaggc      960

ucaaacaucu gcuuaacacg uacagaccga gguugguacu gugauaacgc aggauccgua     1020

ucauuuuucc cacaagcaga aacaugcaaa guacaaucaa accgcguuuu uugugacacc     1080

augaacagca gaacccuccc uucagaagua aaccuaugca acgucgauau auuuaaccca     1140

aaauacgauu gcaaaauaau gacaucaaaa accgaugucu caucuucagu aauaaccucu     1200

cuaggagcaa uagucucaug uuacggaaaa acaaaaugca cagcaaguaa uaaaaauaga     1260

ggaauaauaa aaacauucuc uaauggcugc gacuacguau ccaauaaagg cguugacaca     1320

guauccguag gcaacacacu cuacuauguu aacaaacaag aaggaaaaag uuuauacguu     1380

aaaggagaac caauuauaaa cuuuuacgac ccacucguau ucccaucuga ugaauuugac     1440

gcaucaaucu cacaaguaaa ugaaaaaauc aaucaguccc uugccuuuau aagaaaauca     1500

gaugaacuuu uacacaacgu uaacgccgga aaaucaacaa ccaauauaau gaucacaacc     1560

auaauaauag uuauaauugu aauuuuauua uccuuaauag ccgucggacu acuacuauac     1620

ugcaaagcaa gaucuacacc cguaacccua ucaaaagacc aacuaagugg aauaaauaac     1680

auugcauucu caaauuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4074
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4074
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuaaa ggcaaacgca      120

aucacuacaa uucuaaccgc cgugacauuc ugcuucgccu ccggacaaaa caucaccgaa      180

gaauuuuacc aauccacaug cucggccguc aguaaaggcu accucucggc ucuccgaacc      240

ggcugguaca ccuccgucau caccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacucg acaaauacaa aaacgccguc      360

acagaacucc aacuacuaau gcaaucaaca cccgcuacag gaagcggcuc cgccaucgcc      420

agcggcguag cugucugcaa aguccuccac cucgaaggug aagucaacaa aaucaaauca      480

gcccuacuca gcacaaacaa agccguugua agccuaucca acggcgucuc cguacuaaca      540

uucaaagucc uugaccucaa gaacuacauc gacaaacaac uucucccaau ccuaaacaaa      600

caaagcugcu caauuuccaa caucgaaaca guaaucgaau uucaacaaaa aaacaaccga      660

cuccucgaaa ucacccgcga auuuuccguu aacgccggcg uuacaacccc cgucuccacc      720

uacaugcuca ccaauuccga acuacuauca cucauaaacg acaugccuau cacaaacgac      780

caaaaaaaac uaaugucaaa caauguccaa aucguccgcc agcaaagcua uuccaucaug      840

ugcaucauca aagaggaagu ccucgccuac guaguccaac ugccccucua cggcgucauu      900

gauacccccu gcuggaaacu ccacaccucc ccccucugca ccacaaacac caaagaaggu      960

uccaacaucu gccuaacacg aaccgacaga ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccuguaaa guccagucua accgcgucuu cugcgacaca     1080

augaacucaa gaacccuacc uuccgaagua aaccucugca acguagacau cuucaacccu     1140

aaauacgacu gcaaaaucau gacuucaaaa acagacguaa gcucuuccgu aaucacuucc     1200

cucggcgcca ucguauccug cuacgguaaa accaaaugca ccgccuccaa caaaaaccga     1260

gggaucauaa aaaccuucuc caacggcugc gacuacguau cuaacaaagg cgucgacacc     1320

gucuccgucg gcaacacccu cuauuacgua aacaaacaag agggcaaauc acuauacguc     1380

aaaggcgagc caaucauaaa cuucuaugac ccacucgucu ucccuucaga cgaauuugau     1440

gccagcauca gccaagucaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaagc     1500

gacgaacucc uucacaacgu caacgcaggc aaaucaacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu uauccuacuc agccucaucg caguuggucu ucuccuuuac     1620

ugcaaagccc gcuccacccc cgucacccuc aguaaagacc aacucagcgg aaucaacaac     1680

auagcauucu ccaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4075
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4075
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4076
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4076
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4077
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4077
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4078
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4078
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcuuucu caaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4079
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4079
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4080
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4080
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4081
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4081
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauacuaaa agccaaugca      120

auaacaacca uacuaaccgc cguaacauuu uguuucgcau caggucaaaa cauaaccgaa      180

gaauuuuauc aaucaacaug cucagcagua ucaaaaggau acuuauccgc ucuaagaaca      240

ggaugguaca caaguguaau uacaauagag cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacugacg caaaaguuaa acuuauaaaa caagaacuag auaaauauaa aaaugcagua      360

accgaauuac aacuccuaau gcaauccaca ccugcuaccg guuccggauc agccauagca      420

ucuggaguag ccguaugcaa aguccuccac cuagaaggag aaguaaauaa aaucaaauca      480

gcacuauuau cuaccaauaa agcaguuguc ucacuaucca auggcguauc aguacuaaca      540

uucaaaguau uagaccuuaa aaacuacaua gacaaacaac uauuaccaau ucugaacaaa      600

caauccuguu caauaucaaa caucgaaacg guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa uaacaagaga auuuucagua aaugcaggag uuacaacacc cgucuccacc      720

uacaugcuca caaauucaga auuauuauca cuuauaaacg acaugccaau aacuaacgac      780

caaaaaaaac uaaugucaaa caauguccaa auaguccgac aacaauccua cucaauaaug      840

ugcauuauaa aagaagaagu ccuagccuac guuguccaac uacccuuaua uggaguaaua      900

gauaccccau gcuggaaacu ucauaccucc ccccuaugca caacaaacac aaaagaaggc      960

ucaaacaucu gcuuaacacg uacagaccga gguugguacu gugauaacgc aggauccgua     1020

ucauuuuucc cacaagcaga aacaugcaaa guacaaucaa accgcguuuu uugugacacc     1080

augaacagca gaacccuccc uucagaagua aaccuaugca acgucgauau auuuaaccca     1140

aaauacgauu gcaaaauaau gacaucaaaa accgaugucu caucuucagu aauaaccucu     1200

cuaggagcaa uagucucaug uuacggaaaa acaaaaugca cagcaaguaa uaaaaauaga     1260

ggaauaauaa aaacauucuc uaauggcugc gacuacguau ccaauaaagg cguugacaca     1320

guauccguag gcaacacacu cuacuauguu aacaaacaag aaggaaaaag uuuauacguu     1380

aaaggagaac caauuauaaa cuuuuacgac ccacucguau ucccaucuga ugaauuugac     1440

gcaucaaucu cacaaguaaa ugaaaaaauc aaucaguccc uugccuuuau aagaaaauca     1500

gaugaacuuu uacacaacgu uaacgccgga aaaucaacaa ccaauauaau gaucacaacc     1560

auaauaauag uuauaauugu aauuuuauua uccuuaauag ccgucggacu acuacuauac     1620

ugcaaagcaa gaucuacacc cguaacccua ucaaaagacc aacuaagugg aauaaauaac     1680

auugcauucu caaauuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4082
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4082
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc uaauacuaaa ggcaaacgca      120

aucacuacaa uucuaaccgc cgugacauuc ugcuucgccu ccggacaaaa caucaccgaa      180

gaauuuuacc aauccacaug cucggccguc aguaaaggcu accucucggc ucuccgaacc      240

ggcugguaca ccuccgucau caccaucgaa cucuccaaca ucaaagaaaa caaaugcaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacucg acaaauacaa aaacgccguc      360

acagaacucc aacuacuaau gcaaucaaca cccgcuacag gaagcggcuc cgccaucgcc      420

agcggcguag cugucugcaa aguccuccac cucgaaggug aagucaacaa aaucaaauca      480

gcccuacuca gcacaaacaa agccguugua agccuaucca acggcgucuc cguacuaaca      540

uucaaagucc uugaccucaa gaacuacauc gacaaacaac uucucccaau ccuaaacaaa      600

caaagcugcu caauuuccaa caucgaaaca guaaucgaau uucaacaaaa aaacaaccga      660

cuccucgaaa ucacccgcga auuuuccguu aacgccggcg uuacaacccc cgucuccacc      720

uacaugcuca ccaauuccga acuacuauca cucauaaacg acaugccuau cacaaacgac      780

caaaaaaaac uaaugucaaa caauguccaa aucguccgcc agcaaagcua uuccaucaug      840

ugcaucauca aagaggaagu ccucgccuac guaguccaac ugccccucua cggcgucauu      900

gauacccccu gcuggaaacu ccacaccucc ccccucugca ccacaaacac caaagaaggu      960

uccaacaucu gccuaacacg aaccgacaga ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cccaagcaga aaccuguaaa guccagucua accgcgucuu cugcgacaca     1080

augaacucaa gaacccuacc uuccgaagua aaccucugca acguagacau cuucaacccu     1140

aaauacgacu gcaaaaucau gacuucaaaa acagacguaa gcucuuccgu aaucacuucc     1200

cucggcgcca ucguauccug cuacgguaaa accaaaugca ccgccuccaa caaaaaccga     1260

gggaucauaa aaaccuucuc caacggcugc gacuacguau cuaacaaagg cgucgacacc     1320

gucuccgucg gcaacacccu cuauuacgua aacaaacaag agggcaaauc acuauacguc     1380

aaaggcgagc caaucauaaa cuucuaugac ccacucgucu ucccuucaga cgaauuugau     1440

gccagcauca gccaagucaa cgaaaaaauc aaccaaucac ucgccuucau ccgcaaaagc     1500

gacgaacucc uucacaacgu caacgcaggc aaaucaacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu uauccuacuc agccucaucg caguuggucu ucuccuuuac     1620

ugcaaagccc gcuccacccc cgucacccuc aguaaagacc aacucagcgg aaucaacaac     1680

auagcauucu ccaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4083
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4083
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4084
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4084
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4085
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4085
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4086
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4086
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcuuucucaa     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4087
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4087
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4088
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4088
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4089
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4089
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uacuaaaagc caaugcaaua acaaccauac      120

uaaccgccgu aacauuuugu uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau      180

caacaugcuc agcaguauca aaaggauacu uauccgcucu aagaacagga ugguacacaa      240

guguaauuac aauagagcuc ucaaacauaa aagaaaacaa augcaaugga acugacgcaa      300

aaguuaaacu uauaaaacaa gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac      360

uccuaaugca auccacaccu gcuaccgguu ccggaucagc cauagcaucu ggaguagccg      420

uaugcaaagu ccuccaccua gaaggagaag uaaauaaaau caaaucagca cuauuaucua      480

ccaauaaagc aguugucuca cuauccaaug gcguaucagu acuaacauuc aaaguauuag      540

accuuaaaaa cuacauagac aaacaacuau uaccaauucu gaacaaacaa uccuguucaa      600

uaucaaacau cgaaacggua auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa      660

caagagaauu uucaguaaau gcaggaguua caacacccgu cuccaccuac augcucacaa      720

auucagaauu auuaucacuu auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaaua guccgacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu agccuacguu guccaacuac ccuuauaugg aguaauagau accccaugcu      900

ggaaacuuca uaccuccccc cuaugcacaa caaacacaaa agaaggcuca aacaucugcu      960

uaacacguac agaccgaggu ugguacugug auaacgcagg auccguauca uuuuucccac     1020

aagcagaaac augcaaagua caaucaaacc gcguuuuuug ugacaccaug aacagcagaa     1080

cccucccuuc agaaguaaac cuaugcaacg ucgauauauu uaacccaaaa uacgauugca     1140

aaauaaugac aucaaaaacc gaugucucau cuucaguaau aaccucucua ggagcaauag     1200

ucucauguua cggaaaaaca aaaugcacag caaguaauaa aaauagagga auaauaaaaa     1260

cauucucuaa uggcugcgac uacguaucca auaaaggcgu ugacacagua uccguaggca     1320

acacacucua cuauguuaac aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa     1380

uuauaaacuu uuacgaccca cucguauucc caucugauga auuugacgca ucaaucucac     1440

aaguaaauga aaaaaucaau cagucccuug ccuuuauaag aaaaucagau gaacuuuuac     1500

acaacguuaa cgccggaaaa ucaacaacca auauaaugau cacaaccaua auaauaguua     1560

uaauuguaau uuuauuaucc uuaauagccg ucggacuacu acuauacugc aaagcaagau     1620

cuacacccgu aacccuauca aaagaccaac uaaguggaau aaauaacauu gcauucucaa     1680

auuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4090
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4090
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc      120

uaaccgccgu gacauucugc uucgccuccg gacaaaacau caccgaagaa uuuuaccaau      180

ccacaugcuc ggccgucagu aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu      240

ccgucaucac caucgaacuc uccaacauca aagaaaacaa augcaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacucgaca aauacaaaaa cgccgucaca gaacuccaac      360

uacuaaugca aucaacaccc gcuacaggaa gcggcuccgc caucgccagc ggcguagcug      420

ucugcaaagu ccuccaccuc gaaggugaag ucaacaaaau caaaucagcc cuacucagca      480

caaacaaagc cguuguaagc cuauccaacg gcgucuccgu acuaacauuc aaaguccuug      540

accucaagaa cuacaucgac aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa      600

uuuccaacau cgaaacagua aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca      660

cccgcgaauu uuccguuaac gccggcguua caacccccgu cuccaccuac augcucacca      720

auuccgaacu acuaucacuc auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaauc guccgccagc aaagcuauuc caucaugugc aucaucaaag      840

aggaaguccu cgccuacgua guccaacugc cccucuacgg cgucauugau acccccugcu      900

ggaaacucca caccuccccc cucugcacca caaacaccaa agaagguucc aacaucugcc      960

uaacacgaac cgacagaggc ugguacugcg acaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cuguaaaguc cagucuaacc gcgucuucug cgacacaaug aacucaagaa     1080

cccuaccuuc cgaaguaaac cucugcaacg uagacaucuu caacccuaaa uacgacugca     1140

aaaucaugac uucaaaaaca gacguaagcu cuuccguaau cacuucccuc ggcgccaucg     1200

uauccugcua cgguaaaacc aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa     1260

ccuucuccaa cggcugcgac uacguaucua acaaaggcgu cgacaccguc uccgucggca     1320

acacccucua uuacguaaac aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa     1380

ucauaaacuu cuaugaccca cucgucuucc cuucagacga auuugaugcc agcaucagcc     1440

aagucaacga aaaaaucaac caaucacucg ccuucauccg caaaagcgac gaacuccuuc     1500

acaacgucaa cgcaggcaaa ucaaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucguuau ccuacucagc cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu     1620

ccacccccgu cacccucagu aaagaccaac ucagcggaau caacaacaua gcauucucca     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4091
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4091
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4092
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4092
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4093
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4093
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4094
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4094
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcuuucucaa     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4095
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4095
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4096
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4096
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4097
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4097
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uacuaaaagc caaugcaaua acaaccauac      120

uaaccgccgu aacauuuugu uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau      180

caacaugcuc agcaguauca aaaggauacu uauccgcucu aagaacagga ugguacacaa      240

guguaauuac aauagagcuc ucaaacauaa aagaaaacaa augcaaugga acugacgcaa      300

aaguuaaacu uauaaaacaa gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac      360

uccuaaugca auccacaccu gcuaccgguu ccggaucagc cauagcaucu ggaguagccg      420

uaugcaaagu ccuccaccua gaaggagaag uaaauaaaau caaaucagca cuauuaucua      480

ccaauaaagc aguugucuca cuauccaaug gcguaucagu acuaacauuc aaaguauuag      540

accuuaaaaa cuacauagac aaacaacuau uaccaauucu gaacaaacaa uccuguucaa      600

uaucaaacau cgaaacggua auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa      660

caagagaauu uucaguaaau gcaggaguua caacacccgu cuccaccuac augcucacaa      720

auucagaauu auuaucacuu auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaaua guccgacaac aauccuacuc aauaaugugc auuauaaaag      840

aagaaguccu agccuacguu guccaacuac ccuuauaugg aguaauagau accccaugcu      900

ggaaacuuca uaccuccccc cuaugcacaa caaacacaaa agaaggcuca aacaucugcu      960

uaacacguac agaccgaggu ugguacugug auaacgcagg auccguauca uuuuucccac     1020

aagcagaaac augcaaagua caaucaaacc gcguuuuuug ugacaccaug aacagcagaa     1080

cccucccuuc agaaguaaac cuaugcaacg ucgauauauu uaacccaaaa uacgauugca     1140

aaauaaugac aucaaaaacc gaugucucau cuucaguaau aaccucucua ggagcaauag     1200

ucucauguua cggaaaaaca aaaugcacag caaguaauaa aaauagagga auaauaaaaa     1260

cauucucuaa uggcugcgac uacguaucca auaaaggcgu ugacacagua uccguaggca     1320

acacacucua cuauguuaac aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa     1380

uuauaaacuu uuacgaccca cucguauucc caucugauga auuugacgca ucaaucucac     1440

aaguaaauga aaaaaucaau cagucccuug ccuuuauaag aaaaucagau gaacuuuuac     1500

acaacguuaa cgccggaaaa ucaacaacca auauaaugau cacaaccaua auaauaguua     1560

uaauuguaau uuuauuaucc uuaauagccg ucggacuacu acuauacugc aaagcaagau     1620

cuacacccgu aacccuauca aaagaccaac uaaguggaau aaauaacauu gcauucucaa     1680

auuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4098
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4098
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc      120

uaaccgccgu gacauucugc uucgccuccg gacaaaacau caccgaagaa uuuuaccaau      180

ccacaugcuc ggccgucagu aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu      240

ccgucaucac caucgaacuc uccaacauca aagaaaacaa augcaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacucgaca aauacaaaaa cgccgucaca gaacuccaac      360

uacuaaugca aucaacaccc gcuacaggaa gcggcuccgc caucgccagc ggcguagcug      420

ucugcaaagu ccuccaccuc gaaggugaag ucaacaaaau caaaucagcc cuacucagca      480

caaacaaagc cguuguaagc cuauccaacg gcgucuccgu acuaacauuc aaaguccuug      540

accucaagaa cuacaucgac aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa      600

uuuccaacau cgaaacagua aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca      660

cccgcgaauu uuccguuaac gccggcguua caacccccgu cuccaccuac augcucacca      720

auuccgaacu acuaucacuc auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa      780

ugucaaacaa uguccaaauc guccgccagc aaagcuauuc caucaugugc aucaucaaag      840

aggaaguccu cgccuacgua guccaacugc cccucuacgg cgucauugau acccccugcu      900

ggaaacucca caccuccccc cucugcacca caaacaccaa agaagguucc aacaucugcc      960

uaacacgaac cgacagaggc ugguacugcg acaacgccgg cagcgucucc uucuuccccc     1020

aagcagaaac cuguaaaguc cagucuaacc gcgucuucug cgacacaaug aacucaagaa     1080

cccuaccuuc cgaaguaaac cucugcaacg uagacaucuu caacccuaaa uacgacugca     1140

aaaucaugac uucaaaaaca gacguaagcu cuuccguaau cacuucccuc ggcgccaucg     1200

uauccugcua cgguaaaacc aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa     1260

ccuucuccaa cggcugcgac uacguaucua acaaaggcgu cgacaccguc uccgucggca     1320

acacccucua uuacguaaac aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa     1380

ucauaaacuu cuaugaccca cucgucuucc cuucagacga auuugaugcc agcaucagcc     1440

aagucaacga aaaaaucaac caaucacucg ccuucauccg caaaagcgac gaacuccuuc     1500

acaacgucaa cgcaggcaaa ucaaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucguuau ccuacucagc cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu     1620

ccacccccgu cacccucagu aaagaccaac ucagcggaau caacaacaua gcauucucca     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4099
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4099
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4100
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4100
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4101
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4101
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4102
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4102
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcuuucuc aaacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4103
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4103
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4104
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4104
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4105
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4105
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauacuaaaa gccaaugcaa uaacaaccau acuaaccgcc      120

guaacauuuu guuucgcauc aggucaaaac auaaccgaag aauuuuauca aucaacaugc      180

ucagcaguau caaaaggaua cuuauccgcu cuaagaacag gaugguacac aaguguaauu      240

acaauagagc ucucaaacau aaaagaaaac aaaugcaaug gaacugacgc aaaaguuaaa      300

cuuauaaaac aagaacuaga uaaauauaaa aaugcaguaa ccgaauuaca acuccuaaug      360

caauccacac cugcuaccgg uuccggauca gccauagcau cuggaguagc cguaugcaaa      420

guccuccacc uagaaggaga aguaaauaaa aucaaaucag cacuauuauc uaccaauaaa      480

gcaguugucu cacuauccaa uggcguauca guacuaacau ucaaaguauu agaccuuaaa      540

aacuacauag acaaacaacu auuaccaauu cugaacaaac aauccuguuc aauaucaaac      600

aucgaaacgg uaauagaauu ucaacaaaaa aauaacagau uacuugaaau aacaagagaa      660

uuuucaguaa augcaggagu uacaacaccc gucuccaccu acaugcucac aaauucagaa      720

uuauuaucac uuauaaacga caugccaaua acuaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa uaguccgaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cuagccuacg uuguccaacu acccuuauau ggaguaauag auaccccaug cuggaaacuu      900

cauaccuccc cccuaugcac aacaaacaca aaagaaggcu caaacaucug cuuaacacgu      960

acagaccgag guugguacug ugauaacgca ggauccguau cauuuuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa ccgcguuuuu ugugacacca ugaacagcag aacccucccu     1080

ucagaaguaa accuaugcaa cgucgauaua uuuaacccaa aauacgauug caaaauaaug     1140

acaucaaaaa ccgaugucuc aucuucagua auaaccucuc uaggagcaau agucucaugu     1200

uacggaaaaa caaaaugcac agcaaguaau aaaaauagag gaauaauaaa aacauucucu     1260

aauggcugcg acuacguauc caauaaaggc guugacacag uauccguagg caacacacuc     1320

uacuauguua acaaacaaga aggaaaaagu uuauacguua aaggagaacc aauuauaaac     1380

uuuuacgacc cacucguauu cccaucugau gaauuugacg caucaaucuc acaaguaaau     1440

gaaaaaauca aucagucccu ugccuuuaua agaaaaucag augaacuuuu acacaacguu     1500

aacgccggaa aaucaacaac caauauaaug aucacaacca uaauaauagu uauaauugua     1560

auuuuauuau ccuuaauagc cgucggacua cuacuauacu gcaaagcaag aucuacaccc     1620

guaacccuau caaaagacca acuaagugga auaaauaaca uugcauucuc aaauuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4106
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4106
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuaaag gcaaacgcaa ucacuacaau ucuaaccgcc      120

gugacauucu gcuucgccuc cggacaaaac aucaccgaag aauuuuacca auccacaugc      180

ucggccguca guaaaggcua ccucucggcu cuccgaaccg gcugguacac cuccgucauc      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacucga caaauacaaa aacgccguca cagaacucca acuacuaaug      360

caaucaacac ccgcuacagg aagcggcucc gccaucgcca gcggcguagc ugucugcaaa      420

guccuccacc ucgaagguga agucaacaaa aucaaaucag cccuacucag cacaaacaaa      480

gccguuguaa gccuauccaa cggcgucucc guacuaacau ucaaaguccu ugaccucaag      540

aacuacaucg acaaacaacu ucucccaauc cuaaacaaac aaagcugcuc aauuuccaac      600

aucgaaacag uaaucgaauu ucaacaaaaa aacaaccgac uccucgaaau cacccgcgaa      660

uuuuccguua acgccggcgu uacaaccccc gucuccaccu acaugcucac caauuccgaa      720

cuacuaucac ucauaaacga caugccuauc acaaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa ucguccgcca gcaaagcuau uccaucaugu gcaucaucaa agaggaaguc      840

cucgccuacg uaguccaacu gccccucuac ggcgucauug auacccccug cuggaaacuc      900

cacaccuccc cccucugcac cacaaacacc aaagaagguu ccaacaucug ccuaacacga      960

accgacagag gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accuguaaag uccagucuaa ccgcgucuuc ugcgacacaa ugaacucaag aacccuaccu     1080

uccgaaguaa accucugcaa cguagacauc uucaacccua aauacgacug caaaaucaug     1140

acuucaaaaa cagacguaag cucuuccgua aucacuuccc ucggcgccau cguauccugc     1200

uacgguaaaa ccaaaugcac cgccuccaac aaaaaccgag ggaucauaaa aaccuucucc     1260

aacggcugcg acuacguauc uaacaaaggc gucgacaccg ucuccgucgg caacacccuc     1320

uauuacguaa acaaacaaga gggcaaauca cuauacguca aaggcgagcc aaucauaaac     1380

uucuaugacc cacucgucuu cccuucagac gaauuugaug ccagcaucag ccaagucaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaaagcg acgaacuccu ucacaacguc     1500

aacgcaggca aaucaaccac caacaucaug aucaccacca ucaucaucgu caucaucguu     1560

auccuacuca gccucaucgc aguuggucuu cuccuuuacu gcaaagcccg cuccaccccc     1620

gucacccuca guaaagacca acucagcgga aucaacaaca uagcauucuc caacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4107
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4107
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4108
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4108
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4109
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4109
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4110
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4110
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcuuucuc aaacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4111
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4111
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4112
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4112
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4113
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4113
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauacuaaaa gccaaugcaa uaacaaccau acuaaccgcc      120

guaacauuuu guuucgcauc aggucaaaac auaaccgaag aauuuuauca aucaacaugc      180

ucagcaguau caaaaggaua cuuauccgcu cuaagaacag gaugguacac aaguguaauu      240

acaauagagc ucucaaacau aaaagaaaac aaaugcaaug gaacugacgc aaaaguuaaa      300

cuuauaaaac aagaacuaga uaaauauaaa aaugcaguaa ccgaauuaca acuccuaaug      360

caauccacac cugcuaccgg uuccggauca gccauagcau cuggaguagc cguaugcaaa      420

guccuccacc uagaaggaga aguaaauaaa aucaaaucag cacuauuauc uaccaauaaa      480

gcaguugucu cacuauccaa uggcguauca guacuaacau ucaaaguauu agaccuuaaa      540

aacuacauag acaaacaacu auuaccaauu cugaacaaac aauccuguuc aauaucaaac      600

aucgaaacgg uaauagaauu ucaacaaaaa aauaacagau uacuugaaau aacaagagaa      660

uuuucaguaa augcaggagu uacaacaccc gucuccaccu acaugcucac aaauucagaa      720

uuauuaucac uuauaaacga caugccaaua acuaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa uaguccgaca acaauccuac ucaauaaugu gcauuauaaa agaagaaguc      840

cuagccuacg uuguccaacu acccuuauau ggaguaauag auaccccaug cuggaaacuu      900

cauaccuccc cccuaugcac aacaaacaca aaagaaggcu caaacaucug cuuaacacgu      960

acagaccgag guugguacug ugauaacgca ggauccguau cauuuuuccc acaagcagaa     1020

acaugcaaag uacaaucaaa ccgcguuuuu ugugacacca ugaacagcag aacccucccu     1080

ucagaaguaa accuaugcaa cgucgauaua uuuaacccaa aauacgauug caaaauaaug     1140

acaucaaaaa ccgaugucuc aucuucagua auaaccucuc uaggagcaau agucucaugu     1200

uacggaaaaa caaaaugcac agcaaguaau aaaaauagag gaauaauaaa aacauucucu     1260

aauggcugcg acuacguauc caauaaaggc guugacacag uauccguagg caacacacuc     1320

uacuauguua acaaacaaga aggaaaaagu uuauacguua aaggagaacc aauuauaaac     1380

uuuuacgacc cacucguauu cccaucugau gaauuugacg caucaaucuc acaaguaaau     1440

gaaaaaauca aucagucccu ugccuuuaua agaaaaucag augaacuuuu acacaacguu     1500

aacgccggaa aaucaacaac caauauaaug aucacaacca uaauaauagu uauaauugua     1560

auuuuauuau ccuuaauagc cgucggacua cuacuauacu gcaaagcaag aucuacaccc     1620

guaacccuau caaaagacca acuaagugga auaaauaaca uugcauucuc aaauuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4114
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4114
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu aauacuaaag gcaaacgcaa ucacuacaau ucuaaccgcc      120

gugacauucu gcuucgccuc cggacaaaac aucaccgaag aauuuuacca auccacaugc      180

ucggccguca guaaaggcua ccucucggcu cuccgaaccg gcugguacac cuccgucauc      240

accaucgaac ucuccaacau caaagaaaac aaaugcaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacucga caaauacaaa aacgccguca cagaacucca acuacuaaug      360

caaucaacac ccgcuacagg aagcggcucc gccaucgcca gcggcguagc ugucugcaaa      420

guccuccacc ucgaagguga agucaacaaa aucaaaucag cccuacucag cacaaacaaa      480

gccguuguaa gccuauccaa cggcgucucc guacuaacau ucaaaguccu ugaccucaag      540

aacuacaucg acaaacaacu ucucccaauc cuaaacaaac aaagcugcuc aauuuccaac      600

aucgaaacag uaaucgaauu ucaacaaaaa aacaaccgac uccucgaaau cacccgcgaa      660

uuuuccguua acgccggcgu uacaaccccc gucuccaccu acaugcucac caauuccgaa      720

cuacuaucac ucauaaacga caugccuauc acaaacgacc aaaaaaaacu aaugucaaac      780

aauguccaaa ucguccgcca gcaaagcuau uccaucaugu gcaucaucaa agaggaaguc      840

cucgccuacg uaguccaacu gccccucuac ggcgucauug auacccccug cuggaaacuc      900

cacaccuccc cccucugcac cacaaacacc aaagaagguu ccaacaucug ccuaacacga      960

accgacagag gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc ccaagcagaa     1020

accuguaaag uccagucuaa ccgcgucuuc ugcgacacaa ugaacucaag aacccuaccu     1080

uccgaaguaa accucugcaa cguagacauc uucaacccua aauacgacug caaaaucaug     1140

acuucaaaaa cagacguaag cucuuccgua aucacuuccc ucggcgccau cguauccugc     1200

uacgguaaaa ccaaaugcac cgccuccaac aaaaaccgag ggaucauaaa aaccuucucc     1260

aacggcugcg acuacguauc uaacaaaggc gucgacaccg ucuccgucgg caacacccuc     1320

uauuacguaa acaaacaaga gggcaaauca cuauacguca aaggcgagcc aaucauaaac     1380

uucuaugacc cacucgucuu cccuucagac gaauuugaug ccagcaucag ccaagucaac     1440

gaaaaaauca accaaucacu cgccuucauc cgcaaaagcg acgaacuccu ucacaacguc     1500

aacgcaggca aaucaaccac caacaucaug aucaccacca ucaucaucgu caucaucguu     1560

auccuacuca gccucaucgc aguuggucuu cuccuuuacu gcaaagcccg cuccaccccc     1620

gucacccuca guaaagacca acucagcgga aucaacaaca uagcauucuc caacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4115
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4115
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4116
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4116
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4117
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4117
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4118
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4118
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cuuucucaaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4119
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4119
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4120
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4120
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4121
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4121
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau acuaaaagcc      120

aaugcaauaa caaccauacu aaccgccgua acauuuuguu ucgcaucagg ucaaaacaua      180

accgaagaau uuuaucaauc aacaugcuca gcaguaucaa aaggauacuu auccgcucua      240

agaacaggau gguacacaag uguaauuaca auagagcucu caaacauaaa agaaaacaaa      300

ugcaauggaa cugacgcaaa aguuaaacuu auaaaacaag aacuagauaa auauaaaaau      360

gcaguaaccg aauuacaacu ccuaaugcaa uccacaccug cuaccgguuc cggaucagcc      420

auagcaucug gaguagccgu augcaaaguc cuccaccuag aaggagaagu aaauaaaauc      480

aaaucagcac uauuaucuac caauaaagca guugucucac uauccaaugg cguaucagua      540

cuaacauuca aaguauuaga ccuuaaaaac uacauagaca aacaacuauu accaauucug      600

aacaaacaau ccuguucaau aucaaacauc gaaacgguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaauaac aagagaauuu ucaguaaaug caggaguuac aacacccguc      720

uccaccuaca ugcucacaaa uucagaauua uuaucacuua uaaacgacau gccaauaacu      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaauag uccgacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccua gccuacguug uccaacuacc cuuauaugga      900

guaauagaua ccccaugcug gaaacuucau accucccccc uaugcacaac aaacacaaaa      960

gaaggcucaa acaucugcuu aacacguaca gaccgagguu gguacuguga uaacgcagga     1020

uccguaucau uuuucccaca agcagaaaca ugcaaaguac aaucaaaccg cguuuuuugu     1080

gacaccauga acagcagaac ccucccuuca gaaguaaacc uaugcaacgu cgauauauuu     1140

aacccaaaau acgauugcaa aauaaugaca ucaaaaaccg augucucauc uucaguaaua     1200

accucucuag gagcaauagu cucauguuac ggaaaaacaa aaugcacagc aaguaauaaa     1260

aauagaggaa uaauaaaaac auucucuaau ggcugcgacu acguauccaa uaaaggcguu     1320

gacacaguau ccguaggcaa cacacucuac uauguuaaca aacaagaagg aaaaaguuua     1380

uacguuaaag gagaaccaau uauaaacuuu uacgacccac ucguauuccc aucugaugaa     1440

uuugacgcau caaucucaca aguaaaugaa aaaaucaauc agucccuugc cuuuauaaga     1500

aaaucagaug aacuuuuaca caacguuaac gccggaaaau caacaaccaa uauaaugauc     1560

acaaccauaa uaauaguuau aauuguaauu uuauuauccu uaauagccgu cggacuacua     1620

cuauacugca aagcaagauc uacacccgua acccuaucaa aagaccaacu aaguggaaua     1680

aauaacauug cauucucaaa uuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4122
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4122
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuaaaggca      120

aacgcaauca cuacaauucu aaccgccgug acauucugcu ucgccuccgg acaaaacauc      180

accgaagaau uuuaccaauc cacaugcucg gccgucagua aaggcuaccu cucggcucuc      240

cgaaccggcu gguacaccuc cgucaucacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgccaa agucaaacua aucaaacaag aacucgacaa auacaaaaac      360

gccgucacag aacuccaacu acuaaugcaa ucaacacccg cuacaggaag cggcuccgcc      420

aucgccagcg gcguagcugu cugcaaaguc cuccaccucg aaggugaagu caacaaaauc      480

aaaucagccc uacucagcac aaacaaagcc guuguaagcc uauccaacgg cgucuccgua      540

cuaacauuca aaguccuuga ccucaagaac uacaucgaca aacaacuucu cccaauccua      600

aacaaacaaa gcugcucaau uuccaacauc gaaacaguaa ucgaauuuca acaaaaaaac      660

aaccgacucc ucgaaaucac ccgcgaauuu uccguuaacg ccggcguuac aacccccguc      720

uccaccuaca ugcucaccaa uuccgaacua cuaucacuca uaaacgacau gccuaucaca      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaaucg uccgccagca aagcuauucc      840

aucaugugca ucaucaaaga ggaaguccuc gccuacguag uccaacugcc ccucuacggc      900

gucauugaua cccccugcug gaaacuccac accucccccc ucugcaccac aaacaccaaa      960

gaagguucca acaucugccu aacacgaacc gacagaggcu gguacugcga caacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc uguaaagucc agucuaaccg cgucuucugc     1080

gacacaauga acucaagaac ccuaccuucc gaaguaaacc ucugcaacgu agacaucuuc     1140

aacccuaaau acgacugcaa aaucaugacu ucaaaaacag acguaagcuc uuccguaauc     1200

acuucccucg gcgccaucgu auccugcuac gguaaaacca aaugcaccgc cuccaacaaa     1260

aaccgaggga ucauaaaaac cuucuccaac ggcugcgacu acguaucuaa caaaggcguc     1320

gacaccgucu ccgucggcaa cacccucuau uacguaaaca aacaagaggg caaaucacua     1380

uacgucaaag gcgagccaau cauaaacuuc uaugacccac ucgucuuccc uucagacgaa     1440

uuugaugcca gcaucagcca agucaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaaagcgacg aacuccuuca caacgucaac gcaggcaaau caaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucguuauc cuacucagcc ucaucgcagu uggucuucuc     1620

cuuuacugca aagcccgcuc cacccccguc acccucagua aagaccaacu cagcggaauc     1680

aacaacauag cauucuccaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4123
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4123
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4124
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4124
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4125
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4125
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4126
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4126
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cuuucucaaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4127
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4127
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4128
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4128
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4129
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4129
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau acuaaaagcc      120

aaugcaauaa caaccauacu aaccgccgua acauuuuguu ucgcaucagg ucaaaacaua      180

accgaagaau uuuaucaauc aacaugcuca gcaguaucaa aaggauacuu auccgcucua      240

agaacaggau gguacacaag uguaauuaca auagagcucu caaacauaaa agaaaacaaa      300

ugcaauggaa cugacgcaaa aguuaaacuu auaaaacaag aacuagauaa auauaaaaau      360

gcaguaaccg aauuacaacu ccuaaugcaa uccacaccug cuaccgguuc cggaucagcc      420

auagcaucug gaguagccgu augcaaaguc cuccaccuag aaggagaagu aaauaaaauc      480

aaaucagcac uauuaucuac caauaaagca guugucucac uauccaaugg cguaucagua      540

cuaacauuca aaguauuaga ccuuaaaaac uacauagaca aacaacuauu accaauucug      600

aacaaacaau ccuguucaau aucaaacauc gaaacgguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaauaac aagagaauuu ucaguaaaug caggaguuac aacacccguc      720

uccaccuaca ugcucacaaa uucagaauua uuaucacuua uaaacgacau gccaauaacu      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaauag uccgacaaca auccuacuca      840

auaaugugca uuauaaaaga agaaguccua gccuacguug uccaacuacc cuuauaugga      900

guaauagaua ccccaugcug gaaacuucau accucccccc uaugcacaac aaacacaaaa      960

gaaggcucaa acaucugcuu aacacguaca gaccgagguu gguacuguga uaacgcagga     1020

uccguaucau uuuucccaca agcagaaaca ugcaaaguac aaucaaaccg cguuuuuugu     1080

gacaccauga acagcagaac ccucccuuca gaaguaaacc uaugcaacgu cgauauauuu     1140

aacccaaaau acgauugcaa aauaaugaca ucaaaaaccg augucucauc uucaguaaua     1200

accucucuag gagcaauagu cucauguuac ggaaaaacaa aaugcacagc aaguaauaaa     1260

aauagaggaa uaauaaaaac auucucuaau ggcugcgacu acguauccaa uaaaggcguu     1320

gacacaguau ccguaggcaa cacacucuac uauguuaaca aacaagaagg aaaaaguuua     1380

uacguuaaag gagaaccaau uauaaacuuu uacgacccac ucguauuccc aucugaugaa     1440

uuugacgcau caaucucaca aguaaaugaa aaaaucaauc agucccuugc cuuuauaaga     1500

aaaucagaug aacuuuuaca caacguuaac gccggaaaau caacaaccaa uauaaugauc     1560

acaaccauaa uaauaguuau aauuguaauu uuauuauccu uaauagccgu cggacuacua     1620

cuauacugca aagcaagauc uacacccgua acccuaucaa aagaccaacu aaguggaaua     1680

aauaacauug cauucucaaa uuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4130
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4130
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccuaau acuaaaggca      120

aacgcaauca cuacaauucu aaccgccgug acauucugcu ucgccuccgg acaaaacauc      180

accgaagaau uuuaccaauc cacaugcucg gccgucagua aaggcuaccu cucggcucuc      240

cgaaccggcu gguacaccuc cgucaucacc aucgaacucu ccaacaucaa agaaaacaaa      300

ugcaacggca ccgacgccaa agucaaacua aucaaacaag aacucgacaa auacaaaaac      360

gccgucacag aacuccaacu acuaaugcaa ucaacacccg cuacaggaag cggcuccgcc      420

aucgccagcg gcguagcugu cugcaaaguc cuccaccucg aaggugaagu caacaaaauc      480

aaaucagccc uacucagcac aaacaaagcc guuguaagcc uauccaacgg cgucuccgua      540

cuaacauuca aaguccuuga ccucaagaac uacaucgaca aacaacuucu cccaauccua      600

aacaaacaaa gcugcucaau uuccaacauc gaaacaguaa ucgaauuuca acaaaaaaac      660

aaccgacucc ucgaaaucac ccgcgaauuu uccguuaacg ccggcguuac aacccccguc      720

uccaccuaca ugcucaccaa uuccgaacua cuaucacuca uaaacgacau gccuaucaca      780

aacgaccaaa aaaaacuaau gucaaacaau guccaaaucg uccgccagca aagcuauucc      840

aucaugugca ucaucaaaga ggaaguccuc gccuacguag uccaacugcc ccucuacggc      900

gucauugaua cccccugcug gaaacuccac accucccccc ucugcaccac aaacaccaaa      960

gaagguucca acaucugccu aacacgaacc gacagaggcu gguacugcga caacgccggc     1020

agcgucuccu ucuuccccca agcagaaacc uguaaagucc agucuaaccg cgucuucugc     1080

gacacaauga acucaagaac ccuaccuucc gaaguaaacc ucugcaacgu agacaucuuc     1140

aacccuaaau acgacugcaa aaucaugacu ucaaaaacag acguaagcuc uuccguaauc     1200

acuucccucg gcgccaucgu auccugcuac gguaaaacca aaugcaccgc cuccaacaaa     1260

aaccgaggga ucauaaaaac cuucuccaac ggcugcgacu acguaucuaa caaaggcguc     1320

gacaccgucu ccgucggcaa cacccucuau uacguaaaca aacaagaggg caaaucacua     1380

uacgucaaag gcgagccaau cauaaacuuc uaugacccac ucgucuuccc uucagacgaa     1440

uuugaugcca gcaucagcca agucaacgaa aaaaucaacc aaucacucgc cuucauccgc     1500

aaaagcgacg aacuccuuca caacgucaac gcaggcaaau caaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucguuauc cuacucagcc ucaucgcagu uggucuucuc     1620

cuuuacugca aagcccgcuc cacccccguc acccucagua aagaccaacu cagcggaauc     1680

aacaacauag cauucuccaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4131
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4131
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4132
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4132
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4133
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4133
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4134
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4134
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcuu ucucaaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4135
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4135
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4136
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4136
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4137
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4137
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauacu aaaagccaau gcaauaacaa ccauacuaac cgccguaaca      180

uuuuguuucg caucagguca aaacauaacc gaagaauuuu aucaaucaac augcucagca      240

guaucaaaag gauacuuauc cgcucuaaga acaggauggu acacaagugu aauuacaaua      300

gagcucucaa acauaaaaga aaacaaaugc aauggaacug acgcaaaagu uaaacuuaua      360

aaacaagaac uagauaaaua uaaaaaugca guaaccgaau uacaacuccu aaugcaaucc      420

acaccugcua ccgguuccgg aucagccaua gcaucuggag uagccguaug caaaguccuc      480

caccuagaag gagaaguaaa uaaaaucaaa ucagcacuau uaucuaccaa uaaagcaguu      540

gucucacuau ccaauggcgu aucaguacua acauucaaag uauuagaccu uaaaaacuac      600

auagacaaac aacuauuacc aauucugaac aaacaauccu guucaauauc aaacaucgaa      660

acgguaauag aauuucaaca aaaaaauaac agauuacuug aaauaacaag agaauuuuca      720

guaaaugcag gaguuacaac acccgucucc accuacaugc ucacaaauuc agaauuauua      780

ucacuuauaa acgacaugcc aauaacuaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaauagucc gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccuagcc      900

uacguugucc aacuacccuu auauggagua auagauaccc caugcuggaa acuucauacc      960

uccccccuau gcacaacaaa cacaaaagaa ggcucaaaca ucugcuuaac acguacagac     1020

cgagguuggu acugugauaa cgcaggaucc guaucauuuu ucccacaagc agaaacaugc     1080

aaaguacaau caaaccgcgu uuuuugugac accaugaaca gcagaacccu cccuucagaa     1140

guaaaccuau gcaacgucga uauauuuaac ccaaaauacg auugcaaaau aaugacauca     1200

aaaaccgaug ucucaucuuc aguaauaacc ucucuaggag caauagucuc auguuacgga     1260

aaaacaaaau gcacagcaag uaauaaaaau agaggaauaa uaaaaacauu cucuaauggc     1320

ugcgacuacg uauccaauaa aggcguugac acaguauccg uaggcaacac acucuacuau     1380

guuaacaaac aagaaggaaa aaguuuauac guuaaaggag aaccaauuau aaacuuuuac     1440

gacccacucg uauucccauc ugaugaauuu gacgcaucaa ucucacaagu aaaugaaaaa     1500

aucaaucagu cccuugccuu uauaagaaaa ucagaugaac uuuuacacaa cguuaacgcc     1560

ggaaaaucaa caaccaauau aaugaucaca accauaauaa uaguuauaau uguaauuuua     1620

uuauccuuaa uagccgucgg acuacuacua uacugcaaag caagaucuac acccguaacc     1680

cuaucaaaag accaacuaag uggaauaaau aacauugcau ucucaaauua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4138
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4138
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccuaauacu aaaggcaaac gcaaucacua caauucuaac cgccgugaca      180

uucugcuucg ccuccggaca aaacaucacc gaagaauuuu accaauccac augcucggcc      240

gucaguaaag gcuaccucuc ggcucuccga accggcuggu acaccuccgu caucaccauc      300

gaacucucca acaucaaaga aaacaaaugc aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucacagaac uccaacuacu aaugcaauca      420

acacccgcua caggaagcgg cuccgccauc gccagcggcg uagcugucug caaaguccuc      480

caccucgaag gugaagucaa caaaaucaaa ucagcccuac ucagcacaaa caaagccguu      540

guaagccuau ccaacggcgu cuccguacua acauucaaag uccuugaccu caagaacuac      600

aucgacaaac aacuucuccc aauccuaaac aaacaaagcu gcucaauuuc caacaucgaa      660

acaguaaucg aauuucaaca aaaaaacaac cgacuccucg aaaucacccg cgaauuuucc      720

guuaacgccg gcguuacaac ccccgucucc accuacaugc ucaccaauuc cgaacuacua      780

ucacucauaa acgacaugcc uaucacaaac gaccaaaaaa aacuaauguc aaacaauguc      840

caaaucgucc gccagcaaag cuauuccauc augugcauca ucaaagagga aguccucgcc      900

uacguagucc aacugccccu cuacggcguc auugauaccc ccugcuggaa acuccacacc      960

uccccccucu gcaccacaaa caccaaagaa gguuccaaca ucugccuaac acgaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gucuccuucu ucccccaagc agaaaccugu     1080

aaaguccagu cuaaccgcgu cuucugcgac acaaugaacu caagaacccu accuuccgaa     1140

guaaaccucu gcaacguaga caucuucaac ccuaaauacg acugcaaaau caugacuuca     1200

aaaacagacg uaagcucuuc cguaaucacu ucccucggcg ccaucguauc cugcuacggu     1260

aaaaccaaau gcaccgccuc caacaaaaac cgagggauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg uaucuaacaa aggcgucgac accgucuccg ucggcaacac ccucuauuac     1380

guaaacaaac aagagggcaa aucacuauac gucaaaggcg agccaaucau aaacuucuau     1440

gacccacucg ucuucccuuc agacgaauuu gaugccagca ucagccaagu caacgaaaaa     1500

aucaaccaau cacucgccuu cauccgcaaa agcgacgaac uccuucacaa cgucaacgca     1560

ggcaaaucaa ccaccaacau caugaucacc accaucauca ucgucaucau cguuauccua     1620

cucagccuca ucgcaguugg ucuucuccuu uacugcaaag cccgcuccac ccccgucacc     1680

cucaguaaag accaacucag cggaaucaac aacauagcau ucuccaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4139
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4139
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4140
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4140
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4141
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4141
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4142
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4142
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcuuucuc aaacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4143
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4143
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4144
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4144
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4145
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4145
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauacuaaaa      120

gccaaugcaa uaacaaccau acuaaccgcc guaacauuuu guuucgcauc aggucaaaac      180

auaaccgaag aauuuuauca aucaacaugc ucagcaguau caaaaggaua cuuauccgcu      240

cuaagaacag gaugguacac aaguguaauu acaauagagc ucucaaacau aaaagaaaac      300

aaaugcaaug gaacugacgc aaaaguuaaa cuuauaaaac aagaacuaga uaaauauaaa      360

aaugcaguaa ccgaauuaca acuccuaaug caauccacac cugcuaccgg uuccggauca      420

gccauagcau cuggaguagc cguaugcaaa guccuccacc uagaaggaga aguaaauaaa      480

aucaaaucag cacuauuauc uaccaauaaa gcaguugucu cacuauccaa uggcguauca      540

guacuaacau ucaaaguauu agaccuuaaa aacuacauag acaaacaacu auuaccaauu      600

cugaacaaac aauccuguuc aauaucaaac aucgaaacgg uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau aacaagagaa uuuucaguaa augcaggagu uacaacaccc      720

gucuccaccu acaugcucac aaauucagaa uuauuaucac uuauaaacga caugccaaua      780

acuaacgacc aaaaaaaacu aaugucaaac aauguccaaa uaguccgaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cuagccuacg uuguccaacu acccuuauau      900

ggaguaauag auaccccaug cuggaaacuu cauaccuccc cccuaugcac aacaaacaca      960

aaagaaggcu caaacaucug cuuaacacgu acagaccgag guugguacug ugauaacgca     1020

ggauccguau cauuuuuccc acaagcagaa acaugcaaag uacaaucaaa ccgcguuuuu     1080

ugugacacca ugaacagcag aacccucccu ucagaaguaa accuaugcaa cgucgauaua     1140

uuuaacccaa aauacgauug caaaauaaug acaucaaaaa ccgaugucuc aucuucagua     1200

auaaccucuc uaggagcaau agucucaugu uacggaaaaa caaaaugcac agcaaguaau     1260

aaaaauagag gaauaauaaa aacauucucu aauggcugcg acuacguauc caauaaaggc     1320

guugacacag uauccguagg caacacacuc uacuauguua acaaacaaga aggaaaaagu     1380

uuauacguua aaggagaacc aauuauaaac uuuuacgacc cacucguauu cccaucugau     1440

gaauuugacg caucaaucuc acaaguaaau gaaaaaauca aucagucccu ugccuuuaua     1500

agaaaaucag augaacuuuu acacaacguu aacgccggaa aaucaacaac caauauaaug     1560

aucacaacca uaauaauagu uauaauugua auuuuauuau ccuuaauagc cgucggacua     1620

cuacuauacu gcaaagcaag aucuacaccc guaacccuau caaaagacca acuaagugga     1680

auaaauaaca uugcauucuc aaauuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4146
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4146
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuaaag      120

gcaaacgcaa ucacuacaau ucuaaccgcc gugacauucu gcuucgccuc cggacaaaac      180

aucaccgaag aauuuuacca auccacaugc ucggccguca guaaaggcua ccucucggcu      240

cuccgaaccg gcugguacac cuccgucauc accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacucga caaauacaaa      360

aacgccguca cagaacucca acuacuaaug caaucaacac ccgcuacagg aagcggcucc      420

gccaucgcca gcggcguagc ugucugcaaa guccuccacc ucgaagguga agucaacaaa      480

aucaaaucag cccuacucag cacaaacaaa gccguuguaa gccuauccaa cggcgucucc      540

guacuaacau ucaaaguccu ugaccucaag aacuacaucg acaaacaacu ucucccaauc      600

cuaaacaaac aaagcugcuc aauuuccaac aucgaaacag uaaucgaauu ucaacaaaaa      660

aacaaccgac uccucgaaau cacccgcgaa uuuuccguua acgccggcgu uacaaccccc      720

gucuccaccu acaugcucac caauuccgaa cuacuaucac ucauaaacga caugccuauc      780

acaaacgacc aaaaaaaacu aaugucaaac aauguccaaa ucguccgcca gcaaagcuau      840

uccaucaugu gcaucaucaa agaggaaguc cucgccuacg uaguccaacu gccccucuac      900

ggcgucauug auacccccug cuggaaacuc cacaccuccc cccucugcac cacaaacacc      960

aaagaagguu ccaacaucug ccuaacacga accgacagag gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accuguaaag uccagucuaa ccgcgucuuc     1080

ugcgacacaa ugaacucaag aacccuaccu uccgaaguaa accucugcaa cguagacauc     1140

uucaacccua aauacgacug caaaaucaug acuucaaaaa cagacguaag cucuuccgua     1200

aucacuuccc ucggcgccau cguauccugc uacgguaaaa ccaaaugcac cgccuccaac     1260

aaaaaccgag ggaucauaaa aaccuucucc aacggcugcg acuacguauc uaacaaaggc     1320

gucgacaccg ucuccgucgg caacacccuc uauuacguaa acaaacaaga gggcaaauca     1380

cuauacguca aaggcgagcc aaucauaaac uucuaugacc cacucgucuu cccuucagac     1440

gaauuugaug ccagcaucag ccaagucaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaaagcg acgaacuccu ucacaacguc aacgcaggca aaucaaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguu auccuacuca gccucaucgc aguuggucuu     1620

cuccuuuacu gcaaagcccg cuccaccccc gucacccuca guaaagacca acucagcgga     1680

aucaacaaca uagcauucuc caacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4147
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4147
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4148
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4148
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4149
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4149
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4150
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4150
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcuuucuc aaacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4151
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4151
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4152
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4152
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4153
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4153
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauacuaaaa      120

gccaaugcaa uaacaaccau acuaaccgcc guaacauuuu guuucgcauc aggucaaaac      180

auaaccgaag aauuuuauca aucaacaugc ucagcaguau caaaaggaua cuuauccgcu      240

cuaagaacag gaugguacac aaguguaauu acaauagagc ucucaaacau aaaagaaaac      300

aaaugcaaug gaacugacgc aaaaguuaaa cuuauaaaac aagaacuaga uaaauauaaa      360

aaugcaguaa ccgaauuaca acuccuaaug caauccacac cugcuaccgg uuccggauca      420

gccauagcau cuggaguagc cguaugcaaa guccuccacc uagaaggaga aguaaauaaa      480

aucaaaucag cacuauuauc uaccaauaaa gcaguugucu cacuauccaa uggcguauca      540

guacuaacau ucaaaguauu agaccuuaaa aacuacauag acaaacaacu auuaccaauu      600

cugaacaaac aauccuguuc aauaucaaac aucgaaacgg uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau aacaagagaa uuuucaguaa augcaggagu uacaacaccc      720

gucuccaccu acaugcucac aaauucagaa uuauuaucac uuauaaacga caugccaaua      780

acuaacgacc aaaaaaaacu aaugucaaac aauguccaaa uaguccgaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cuagccuacg uuguccaacu acccuuauau      900

ggaguaauag auaccccaug cuggaaacuu cauaccuccc cccuaugcac aacaaacaca      960

aaagaaggcu caaacaucug cuuaacacgu acagaccgag guugguacug ugauaacgca     1020

ggauccguau cauuuuuccc acaagcagaa acaugcaaag uacaaucaaa ccgcguuuuu     1080

ugugacacca ugaacagcag aacccucccu ucagaaguaa accuaugcaa cgucgauaua     1140

uuuaacccaa aauacgauug caaaauaaug acaucaaaaa ccgaugucuc aucuucagua     1200

auaaccucuc uaggagcaau agucucaugu uacggaaaaa caaaaugcac agcaaguaau     1260

aaaaauagag gaauaauaaa aacauucucu aauggcugcg acuacguauc caauaaaggc     1320

guugacacag uauccguagg caacacacuc uacuauguua acaaacaaga aggaaaaagu     1380

uuauacguua aaggagaacc aauuauaaac uuuuacgacc cacucguauu cccaucugau     1440

gaauuugacg caucaaucuc acaaguaaau gaaaaaauca aucagucccu ugccuuuaua     1500

agaaaaucag augaacuuuu acacaacguu aacgccggaa aaucaacaac caauauaaug     1560

aucacaacca uaauaauagu uauaauugua auuuuauuau ccuuaauagc cgucggacua     1620

cuacuauacu gcaaagcaag aucuacaccc guaacccuau caaaagacca acuaagugga     1680

auaaauaaca uugcauucuc aaauuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4154
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4154
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuaaag      120

gcaaacgcaa ucacuacaau ucuaaccgcc gugacauucu gcuucgccuc cggacaaaac      180

aucaccgaag aauuuuacca auccacaugc ucggccguca guaaaggcua ccucucggcu      240

cuccgaaccg gcugguacac cuccgucauc accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacucga caaauacaaa      360

aacgccguca cagaacucca acuacuaaug caaucaacac ccgcuacagg aagcggcucc      420

gccaucgcca gcggcguagc ugucugcaaa guccuccacc ucgaagguga agucaacaaa      480

aucaaaucag cccuacucag cacaaacaaa gccguuguaa gccuauccaa cggcgucucc      540

guacuaacau ucaaaguccu ugaccucaag aacuacaucg acaaacaacu ucucccaauc      600

cuaaacaaac aaagcugcuc aauuuccaac aucgaaacag uaaucgaauu ucaacaaaaa      660

aacaaccgac uccucgaaau cacccgcgaa uuuuccguua acgccggcgu uacaaccccc      720

gucuccaccu acaugcucac caauuccgaa cuacuaucac ucauaaacga caugccuauc      780

acaaacgacc aaaaaaaacu aaugucaaac aauguccaaa ucguccgcca gcaaagcuau      840

uccaucaugu gcaucaucaa agaggaaguc cucgccuacg uaguccaacu gccccucuac      900

ggcgucauug auacccccug cuggaaacuc cacaccuccc cccucugcac cacaaacacc      960

aaagaagguu ccaacaucug ccuaacacga accgacagag gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accuguaaag uccagucuaa ccgcgucuuc     1080

ugcgacacaa ugaacucaag aacccuaccu uccgaaguaa accucugcaa cguagacauc     1140

uucaacccua aauacgacug caaaaucaug acuucaaaaa cagacguaag cucuuccgua     1200

aucacuuccc ucggcgccau cguauccugc uacgguaaaa ccaaaugcac cgccuccaac     1260

aaaaaccgag ggaucauaaa aaccuucucc aacggcugcg acuacguauc uaacaaaggc     1320

gucgacaccg ucuccgucgg caacacccuc uauuacguaa acaaacaaga gggcaaauca     1380

cuauacguca aaggcgagcc aaucauaaac uucuaugacc cacucgucuu cccuucagac     1440

gaauuugaug ccagcaucag ccaagucaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaaagcg acgaacuccu ucacaacguc aacgcaggca aaucaaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguu auccuacuca gccucaucgc aguuggucuu     1620

cuccuuuacu gcaaagcccg cuccaccccc gucacccuca guaaagacca acucagcgga     1680

aucaacaaca uagcauucuc caacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4155
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4155
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4156
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4156
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4157
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4157
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4158
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4158
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcuuucuc aaacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4159
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4159
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4160
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4160
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4161
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4161
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauacuaaaa      120

gccaaugcaa uaacaaccau acuaaccgcc guaacauuuu guuucgcauc aggucaaaac      180

auaaccgaag aauuuuauca aucaacaugc ucagcaguau caaaaggaua cuuauccgcu      240

cuaagaacag gaugguacac aaguguaauu acaauagagc ucucaaacau aaaagaaaac      300

aaaugcaaug gaacugacgc aaaaguuaaa cuuauaaaac aagaacuaga uaaauauaaa      360

aaugcaguaa ccgaauuaca acuccuaaug caauccacac cugcuaccgg uuccggauca      420

gccauagcau cuggaguagc cguaugcaaa guccuccacc uagaaggaga aguaaauaaa      480

aucaaaucag cacuauuauc uaccaauaaa gcaguugucu cacuauccaa uggcguauca      540

guacuaacau ucaaaguauu agaccuuaaa aacuacauag acaaacaacu auuaccaauu      600

cugaacaaac aauccuguuc aauaucaaac aucgaaacgg uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau aacaagagaa uuuucaguaa augcaggagu uacaacaccc      720

gucuccaccu acaugcucac aaauucagaa uuauuaucac uuauaaacga caugccaaua      780

acuaacgacc aaaaaaaacu aaugucaaac aauguccaaa uaguccgaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cuagccuacg uuguccaacu acccuuauau      900

ggaguaauag auaccccaug cuggaaacuu cauaccuccc cccuaugcac aacaaacaca      960

aaagaaggcu caaacaucug cuuaacacgu acagaccgag guugguacug ugauaacgca     1020

ggauccguau cauuuuuccc acaagcagaa acaugcaaag uacaaucaaa ccgcguuuuu     1080

ugugacacca ugaacagcag aacccucccu ucagaaguaa accuaugcaa cgucgauaua     1140

uuuaacccaa aauacgauug caaaauaaug acaucaaaaa ccgaugucuc aucuucagua     1200

auaaccucuc uaggagcaau agucucaugu uacggaaaaa caaaaugcac agcaaguaau     1260

aaaaauagag gaauaauaaa aacauucucu aauggcugcg acuacguauc caauaaaggc     1320

guugacacag uauccguagg caacacacuc uacuauguua acaaacaaga aggaaaaagu     1380

uuauacguua aaggagaacc aauuauaaac uuuuacgacc cacucguauu cccaucugau     1440

gaauuugacg caucaaucuc acaaguaaau gaaaaaauca aucagucccu ugccuuuaua     1500

agaaaaucag augaacuuuu acacaacguu aacgccggaa aaucaacaac caauauaaug     1560

aucacaacca uaauaauagu uauaauugua auuuuauuau ccuuaauagc cgucggacua     1620

cuacuauacu gcaaagcaag aucuacaccc guaacccuau caaaagacca acuaagugga     1680

auaaauaaca uugcauucuc aaauuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4162
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4162
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuaaag      120

gcaaacgcaa ucacuacaau ucuaaccgcc gugacauucu gcuucgccuc cggacaaaac      180

aucaccgaag aauuuuacca auccacaugc ucggccguca guaaaggcua ccucucggcu      240

cuccgaaccg gcugguacac cuccgucauc accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacucga caaauacaaa      360

aacgccguca cagaacucca acuacuaaug caaucaacac ccgcuacagg aagcggcucc      420

gccaucgcca gcggcguagc ugucugcaaa guccuccacc ucgaagguga agucaacaaa      480

aucaaaucag cccuacucag cacaaacaaa gccguuguaa gccuauccaa cggcgucucc      540

guacuaacau ucaaaguccu ugaccucaag aacuacaucg acaaacaacu ucucccaauc      600

cuaaacaaac aaagcugcuc aauuuccaac aucgaaacag uaaucgaauu ucaacaaaaa      660

aacaaccgac uccucgaaau cacccgcgaa uuuuccguua acgccggcgu uacaaccccc      720

gucuccaccu acaugcucac caauuccgaa cuacuaucac ucauaaacga caugccuauc      780

acaaacgacc aaaaaaaacu aaugucaaac aauguccaaa ucguccgcca gcaaagcuau      840

uccaucaugu gcaucaucaa agaggaaguc cucgccuacg uaguccaacu gccccucuac      900

ggcgucauug auacccccug cuggaaacuc cacaccuccc cccucugcac cacaaacacc      960

aaagaagguu ccaacaucug ccuaacacga accgacagag gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accuguaaag uccagucuaa ccgcgucuuc     1080

ugcgacacaa ugaacucaag aacccuaccu uccgaaguaa accucugcaa cguagacauc     1140

uucaacccua aauacgacug caaaaucaug acuucaaaaa cagacguaag cucuuccgua     1200

aucacuuccc ucggcgccau cguauccugc uacgguaaaa ccaaaugcac cgccuccaac     1260

aaaaaccgag ggaucauaaa aaccuucucc aacggcugcg acuacguauc uaacaaaggc     1320

gucgacaccg ucuccgucgg caacacccuc uauuacguaa acaaacaaga gggcaaauca     1380

cuauacguca aaggcgagcc aaucauaaac uucuaugacc cacucgucuu cccuucagac     1440

gaauuugaug ccagcaucag ccaagucaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaaagcg acgaacuccu ucacaacguc aacgcaggca aaucaaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguu auccuacuca gccucaucgc aguuggucuu     1620

cuccuuuacu gcaaagcccg cuccaccccc gucacccuca guaaagacca acucagcgga     1680

aucaacaaca uagcauucuc caacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4163
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4163
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4164
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4164
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4165
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4165
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4166
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4166
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcuuucuc aaacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4167
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4167
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4168
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4168
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4169
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4169
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauacuaaaa      120

gccaaugcaa uaacaaccau acuaaccgcc guaacauuuu guuucgcauc aggucaaaac      180

auaaccgaag aauuuuauca aucaacaugc ucagcaguau caaaaggaua cuuauccgcu      240

cuaagaacag gaugguacac aaguguaauu acaauagagc ucucaaacau aaaagaaaac      300

aaaugcaaug gaacugacgc aaaaguuaaa cuuauaaaac aagaacuaga uaaauauaaa      360

aaugcaguaa ccgaauuaca acuccuaaug caauccacac cugcuaccgg uuccggauca      420

gccauagcau cuggaguagc cguaugcaaa guccuccacc uagaaggaga aguaaauaaa      480

aucaaaucag cacuauuauc uaccaauaaa gcaguugucu cacuauccaa uggcguauca      540

guacuaacau ucaaaguauu agaccuuaaa aacuacauag acaaacaacu auuaccaauu      600

cugaacaaac aauccuguuc aauaucaaac aucgaaacgg uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau aacaagagaa uuuucaguaa augcaggagu uacaacaccc      720

gucuccaccu acaugcucac aaauucagaa uuauuaucac uuauaaacga caugccaaua      780

acuaacgacc aaaaaaaacu aaugucaaac aauguccaaa uaguccgaca acaauccuac      840

ucaauaaugu gcauuauaaa agaagaaguc cuagccuacg uuguccaacu acccuuauau      900

ggaguaauag auaccccaug cuggaaacuu cauaccuccc cccuaugcac aacaaacaca      960

aaagaaggcu caaacaucug cuuaacacgu acagaccgag guugguacug ugauaacgca     1020

ggauccguau cauuuuuccc acaagcagaa acaugcaaag uacaaucaaa ccgcguuuuu     1080

ugugacacca ugaacagcag aacccucccu ucagaaguaa accuaugcaa cgucgauaua     1140

uuuaacccaa aauacgauug caaaauaaug acaucaaaaa ccgaugucuc aucuucagua     1200

auaaccucuc uaggagcaau agucucaugu uacggaaaaa caaaaugcac agcaaguaau     1260

aaaaauagag gaauaauaaa aacauucucu aauggcugcg acuacguauc caauaaaggc     1320

guugacacag uauccguagg caacacacuc uacuauguua acaaacaaga aggaaaaagu     1380

uuauacguua aaggagaacc aauuauaaac uuuuacgacc cacucguauu cccaucugau     1440

gaauuugacg caucaaucuc acaaguaaau gaaaaaauca aucagucccu ugccuuuaua     1500

agaaaaucag augaacuuuu acacaacguu aacgccggaa aaucaacaac caauauaaug     1560

aucacaacca uaauaauagu uauaauugua auuuuauuau ccuuaauagc cgucggacua     1620

cuacuauacu gcaaagcaag aucuacaccc guaacccuau caaaagacca acuaagugga     1680

auaaauaaca uugcauucuc aaauuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4170
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4170
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu aauacuaaag      120

gcaaacgcaa ucacuacaau ucuaaccgcc gugacauucu gcuucgccuc cggacaaaac      180

aucaccgaag aauuuuacca auccacaugc ucggccguca guaaaggcua ccucucggcu      240

cuccgaaccg gcugguacac cuccgucauc accaucgaac ucuccaacau caaagaaaac      300

aaaugcaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacucga caaauacaaa      360

aacgccguca cagaacucca acuacuaaug caaucaacac ccgcuacagg aagcggcucc      420

gccaucgcca gcggcguagc ugucugcaaa guccuccacc ucgaagguga agucaacaaa      480

aucaaaucag cccuacucag cacaaacaaa gccguuguaa gccuauccaa cggcgucucc      540

guacuaacau ucaaaguccu ugaccucaag aacuacaucg acaaacaacu ucucccaauc      600

cuaaacaaac aaagcugcuc aauuuccaac aucgaaacag uaaucgaauu ucaacaaaaa      660

aacaaccgac uccucgaaau cacccgcgaa uuuuccguua acgccggcgu uacaaccccc      720

gucuccaccu acaugcucac caauuccgaa cuacuaucac ucauaaacga caugccuauc      780

acaaacgacc aaaaaaaacu aaugucaaac aauguccaaa ucguccgcca gcaaagcuau      840

uccaucaugu gcaucaucaa agaggaaguc cucgccuacg uaguccaacu gccccucuac      900

ggcgucauug auacccccug cuggaaacuc cacaccuccc cccucugcac cacaaacacc      960

aaagaagguu ccaacaucug ccuaacacga accgacagag gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc ccaagcagaa accuguaaag uccagucuaa ccgcgucuuc     1080

ugcgacacaa ugaacucaag aacccuaccu uccgaaguaa accucugcaa cguagacauc     1140

uucaacccua aauacgacug caaaaucaug acuucaaaaa cagacguaag cucuuccgua     1200

aucacuuccc ucggcgccau cguauccugc uacgguaaaa ccaaaugcac cgccuccaac     1260

aaaaaccgag ggaucauaaa aaccuucucc aacggcugcg acuacguauc uaacaaaggc     1320

gucgacaccg ucuccgucgg caacacccuc uauuacguaa acaaacaaga gggcaaauca     1380

cuauacguca aaggcgagcc aaucauaaac uucuaugacc cacucgucuu cccuucagac     1440

gaauuugaug ccagcaucag ccaagucaac gaaaaaauca accaaucacu cgccuucauc     1500

cgcaaaagcg acgaacuccu ucacaacguc aacgcaggca aaucaaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguu auccuacuca gccucaucgc aguuggucuu     1620

cuccuuuacu gcaaagcccg cuccaccccc gucacccuca guaaagacca acucagcgga     1680

aucaacaaca uagcauucuc caacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4171
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4171
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4172
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4172
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4173
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4173
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4174
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4174
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgcu uucucaaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4175
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4175
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4176
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4176
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4177
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4177
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaauac uaaaagccaa ugcaauaaca accauacuaa ccgccguaac auuuuguuuc      240

gcaucagguc aaaacauaac cgaagaauuu uaucaaucaa caugcucagc aguaucaaaa      300

ggauacuuau ccgcucuaag aacaggaugg uacacaagug uaauuacaau agagcucuca      360

aacauaaaag aaaacaaaug caauggaacu gacgcaaaag uuaaacuuau aaaacaagaa      420

cuagauaaau auaaaaaugc aguaaccgaa uuacaacucc uaaugcaauc cacaccugcu      480

accgguuccg gaucagccau agcaucugga guagccguau gcaaaguccu ccaccuagaa      540

ggagaaguaa auaaaaucaa aucagcacua uuaucuacca auaaagcagu ugucucacua      600

uccaauggcg uaucaguacu aacauucaaa guauuagacc uuaaaaacua cauagacaaa      660

caacuauuac caauucugaa caaacaaucc uguucaauau caaacaucga aacgguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaauaacaa gagaauuuuc aguaaaugca      780

ggaguuacaa cacccgucuc caccuacaug cucacaaauu cagaauuauu aucacuuaua      840

aacgacaugc caauaacuaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaauaguc      900

cgacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccuagc cuacguuguc      960

caacuacccu uauauggagu aauagauacc ccaugcugga aacuucauac cuccccccua     1020

ugcacaacaa acacaaaaga aggcucaaac aucugcuuaa cacguacaga ccgagguugg     1080

uacugugaua acgcaggauc cguaucauuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaaccgcg uuuuuuguga caccaugaac agcagaaccc ucccuucaga aguaaaccua     1200

ugcaacgucg auauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaaccgau     1260

gucucaucuu caguaauaac cucucuagga gcaauagucu cauguuacgg aaaaacaaaa     1320

ugcacagcaa guaauaaaaa uagaggaaua auaaaaacau ucucuaaugg cugcgacuac     1380

guauccaaua aaggcguuga cacaguaucc guaggcaaca cacucuacua uguuaacaaa     1440

caagaaggaa aaaguuuaua cguuaaagga gaaccaauua uaaacuuuua cgacccacuc     1500

guauucccau cugaugaauu ugacgcauca aucucacaag uaaaugaaaa aaucaaucag     1560

ucccuugccu uuauaagaaa aucagaugaa cuuuuacaca acguuaacgc cggaaaauca     1620

acaaccaaua uaaugaucac aaccauaaua auaguuauaa uuguaauuuu auuauccuua     1680

auagccgucg gacuacuacu auacugcaaa gcaagaucua cacccguaac ccuaucaaaa     1740

gaccaacuaa guggaauaaa uaacauugca uucucaaauu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4178
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4178
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uaaaggcaaa cgcaaucacu acaauucuaa ccgccgugac auucugcuuc      240

gccuccggac aaaacaucac cgaagaauuu uaccaaucca caugcucggc cgucaguaaa      300

ggcuaccucu cggcucuccg aaccggcugg uacaccuccg ucaucaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cucgacaaau acaaaaacgc cgucacagaa cuccaacuac uaaugcaauc aacacccgcu      480

acaggaagcg gcuccgccau cgccagcggc guagcugucu gcaaaguccu ccaccucgaa      540

ggugaaguca acaaaaucaa aucagcccua cucagcacaa acaaagccgu uguaagccua      600

uccaacggcg ucuccguacu aacauucaaa guccuugacc ucaagaacua caucgacaaa      660

caacuucucc caauccuaaa caaacaaagc ugcucaauuu ccaacaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ccgacuccuc gaaaucaccc gcgaauuuuc cguuaacgcc      780

ggcguuacaa cccccgucuc caccuacaug cucaccaauu ccgaacuacu aucacucaua      840

aacgacaugc cuaucacaaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaaucguc      900

cgccagcaaa gcuauuccau caugugcauc aucaaagagg aaguccucgc cuacguaguc      960

caacugcccc ucuacggcgu cauugauacc cccugcugga aacuccacac cuccccccuc     1020

ugcaccacaa acaccaaaga agguuccaac aucugccuaa cacgaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccaag cagaaaccug uaaaguccag     1140

ucuaaccgcg ucuucugcga cacaaugaac ucaagaaccc uaccuuccga aguaaaccuc     1200

ugcaacguag acaucuucaa cccuaaauac gacugcaaaa ucaugacuuc aaaaacagac     1260

guaagcucuu ccguaaucac uucccucggc gccaucguau ccugcuacgg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgagggauc auaaaaaccu ucuccaacgg cugcgacuac     1380

guaucuaaca aaggcgucga caccgucucc gucggcaaca cccucuauua cguaaacaaa     1440

caagagggca aaucacuaua cgucaaaggc gagccaauca uaaacuucua ugacccacuc     1500

gucuucccuu cagacgaauu ugaugccagc aucagccaag ucaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa aagcgacgaa cuccuucaca acgucaacgc aggcaaauca     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucguuauccu acucagccuc     1680

aucgcaguug gucuucuccu uuacugcaaa gcccgcucca cccccgucac ccucaguaaa     1740

gaccaacuca gcggaaucaa caacauagca uucuccaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4179
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4179
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4180
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4180
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4181
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4181
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4182
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4182
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgcu uucucaaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4183
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4183
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4184
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4184
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4185
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4185
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaauac uaaaagccaa ugcaauaaca accauacuaa ccgccguaac auuuuguuuc      240

gcaucagguc aaaacauaac cgaagaauuu uaucaaucaa caugcucagc aguaucaaaa      300

ggauacuuau ccgcucuaag aacaggaugg uacacaagug uaauuacaau agagcucuca      360

aacauaaaag aaaacaaaug caauggaacu gacgcaaaag uuaaacuuau aaaacaagaa      420

cuagauaaau auaaaaaugc aguaaccgaa uuacaacucc uaaugcaauc cacaccugcu      480

accgguuccg gaucagccau agcaucugga guagccguau gcaaaguccu ccaccuagaa      540

ggagaaguaa auaaaaucaa aucagcacua uuaucuacca auaaagcagu ugucucacua      600

uccaauggcg uaucaguacu aacauucaaa guauuagacc uuaaaaacua cauagacaaa      660

caacuauuac caauucugaa caaacaaucc uguucaauau caaacaucga aacgguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaauaacaa gagaauuuuc aguaaaugca      780

ggaguuacaa cacccgucuc caccuacaug cucacaaauu cagaauuauu aucacuuaua      840

aacgacaugc caauaacuaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaauaguc      900

cgacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccuagc cuacguuguc      960

caacuacccu uauauggagu aauagauacc ccaugcugga aacuucauac cuccccccua     1020

ugcacaacaa acacaaaaga aggcucaaac aucugcuuaa cacguacaga ccgagguugg     1080

uacugugaua acgcaggauc cguaucauuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaaccgcg uuuuuuguga caccaugaac agcagaaccc ucccuucaga aguaaaccua     1200

ugcaacgucg auauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaaccgau     1260

gucucaucuu caguaauaac cucucuagga gcaauagucu cauguuacgg aaaaacaaaa     1320

ugcacagcaa guaauaaaaa uagaggaaua auaaaaacau ucucuaaugg cugcgacuac     1380

guauccaaua aaggcguuga cacaguaucc guaggcaaca cacucuacua uguuaacaaa     1440

caagaaggaa aaaguuuaua cguuaaagga gaaccaauua uaaacuuuua cgacccacuc     1500

guauucccau cugaugaauu ugacgcauca aucucacaag uaaaugaaaa aaucaaucag     1560

ucccuugccu uuauaagaaa aucagaugaa cuuuuacaca acguuaacgc cggaaaauca     1620

acaaccaaua uaaugaucac aaccauaaua auaguuauaa uuguaauuuu auuauccuua     1680

auagccgucg gacuacuacu auacugcaaa gcaagaucua cacccguaac ccuaucaaaa     1740

gaccaacuaa guggaauaaa uaacauugca uucucaaauu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4186
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4186
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uaaaggcaaa cgcaaucacu acaauucuaa ccgccgugac auucugcuuc      240

gccuccggac aaaacaucac cgaagaauuu uaccaaucca caugcucggc cgucaguaaa      300

ggcuaccucu cggcucuccg aaccggcugg uacaccuccg ucaucaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cucgacaaau acaaaaacgc cgucacagaa cuccaacuac uaaugcaauc aacacccgcu      480

acaggaagcg gcuccgccau cgccagcggc guagcugucu gcaaaguccu ccaccucgaa      540

ggugaaguca acaaaaucaa aucagcccua cucagcacaa acaaagccgu uguaagccua      600

uccaacggcg ucuccguacu aacauucaaa guccuugacc ucaagaacua caucgacaaa      660

caacuucucc caauccuaaa caaacaaagc ugcucaauuu ccaacaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ccgacuccuc gaaaucaccc gcgaauuuuc cguuaacgcc      780

ggcguuacaa cccccgucuc caccuacaug cucaccaauu ccgaacuacu aucacucaua      840

aacgacaugc cuaucacaaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaaucguc      900

cgccagcaaa gcuauuccau caugugcauc aucaaagagg aaguccucgc cuacguaguc      960

caacugcccc ucuacggcgu cauugauacc cccugcugga aacuccacac cuccccccuc     1020

ugcaccacaa acaccaaaga agguuccaac aucugccuaa cacgaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccaag cagaaaccug uaaaguccag     1140

ucuaaccgcg ucuucugcga cacaaugaac ucaagaaccc uaccuuccga aguaaaccuc     1200

ugcaacguag acaucuucaa cccuaaauac gacugcaaaa ucaugacuuc aaaaacagac     1260

guaagcucuu ccguaaucac uucccucggc gccaucguau ccugcuacgg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgagggauc auaaaaaccu ucuccaacgg cugcgacuac     1380

guaucuaaca aaggcgucga caccgucucc gucggcaaca cccucuauua cguaaacaaa     1440

caagagggca aaucacuaua cgucaaaggc gagccaauca uaaacuucua ugacccacuc     1500

gucuucccuu cagacgaauu ugaugccagc aucagccaag ucaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa aagcgacgaa cuccuucaca acgucaacgc aggcaaauca     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucguuauccu acucagccuc     1680

aucgcaguug gucuucuccu uuacugcaaa gcccgcucca cccccgucac ccucaguaaa     1740

gaccaacuca gcggaaucaa caacauagca uucuccaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4187
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4187
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4188
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4188
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4189
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4189
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4190
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4190
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgcu uucucaaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4191
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4191
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4192
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4192
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4193
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4193
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaauac uaaaagccaa ugcaauaaca accauacuaa ccgccguaac auuuuguuuc      240

gcaucagguc aaaacauaac cgaagaauuu uaucaaucaa caugcucagc aguaucaaaa      300

ggauacuuau ccgcucuaag aacaggaugg uacacaagug uaauuacaau agagcucuca      360

aacauaaaag aaaacaaaug caauggaacu gacgcaaaag uuaaacuuau aaaacaagaa      420

cuagauaaau auaaaaaugc aguaaccgaa uuacaacucc uaaugcaauc cacaccugcu      480

accgguuccg gaucagccau agcaucugga guagccguau gcaaaguccu ccaccuagaa      540

ggagaaguaa auaaaaucaa aucagcacua uuaucuacca auaaagcagu ugucucacua      600

uccaauggcg uaucaguacu aacauucaaa guauuagacc uuaaaaacua cauagacaaa      660

caacuauuac caauucugaa caaacaaucc uguucaauau caaacaucga aacgguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaauaacaa gagaauuuuc aguaaaugca      780

ggaguuacaa cacccgucuc caccuacaug cucacaaauu cagaauuauu aucacuuaua      840

aacgacaugc caauaacuaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaauaguc      900

cgacaacaau ccuacucaau aaugugcauu auaaaagaag aaguccuagc cuacguuguc      960

caacuacccu uauauggagu aauagauacc ccaugcugga aacuucauac cuccccccua     1020

ugcacaacaa acacaaaaga aggcucaaac aucugcuuaa cacguacaga ccgagguugg     1080

uacugugaua acgcaggauc cguaucauuu uucccacaag cagaaacaug caaaguacaa     1140

ucaaaccgcg uuuuuuguga caccaugaac agcagaaccc ucccuucaga aguaaaccua     1200

ugcaacgucg auauauuuaa cccaaaauac gauugcaaaa uaaugacauc aaaaaccgau     1260

gucucaucuu caguaauaac cucucuagga gcaauagucu cauguuacgg aaaaacaaaa     1320

ugcacagcaa guaauaaaaa uagaggaaua auaaaaacau ucucuaaugg cugcgacuac     1380

guauccaaua aaggcguuga cacaguaucc guaggcaaca cacucuacua uguuaacaaa     1440

caagaaggaa aaaguuuaua cguuaaagga gaaccaauua uaaacuuuua cgacccacuc     1500

guauucccau cugaugaauu ugacgcauca aucucacaag uaaaugaaaa aaucaaucag     1560

ucccuugccu uuauaagaaa aucagaugaa cuuuuacaca acguuaacgc cggaaaauca     1620

acaaccaaua uaaugaucac aaccauaaua auaguuauaa uuguaauuuu auuauccuua     1680

auagccgucg gacuacuacu auacugcaaa gcaagaucua cacccguaac ccuaucaaaa     1740

gaccaacuaa guggaauaaa uaacauugca uucucaaauu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4194
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4194
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccuaauac uaaaggcaaa cgcaaucacu acaauucuaa ccgccgugac auucugcuuc      240

gccuccggac aaaacaucac cgaagaauuu uaccaaucca caugcucggc cgucaguaaa      300

ggcuaccucu cggcucuccg aaccggcugg uacaccuccg ucaucaccau cgaacucucc      360

aacaucaaag aaaacaaaug caacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cucgacaaau acaaaaacgc cgucacagaa cuccaacuac uaaugcaauc aacacccgcu      480

acaggaagcg gcuccgccau cgccagcggc guagcugucu gcaaaguccu ccaccucgaa      540

ggugaaguca acaaaaucaa aucagcccua cucagcacaa acaaagccgu uguaagccua      600

uccaacggcg ucuccguacu aacauucaaa guccuugacc ucaagaacua caucgacaaa      660

caacuucucc caauccuaaa caaacaaagc ugcucaauuu ccaacaucga aacaguaauc      720

gaauuucaac aaaaaaacaa ccgacuccuc gaaaucaccc gcgaauuuuc cguuaacgcc      780

ggcguuacaa cccccgucuc caccuacaug cucaccaauu ccgaacuacu aucacucaua      840

aacgacaugc cuaucacaaa cgaccaaaaa aaacuaaugu caaacaaugu ccaaaucguc      900

cgccagcaaa gcuauuccau caugugcauc aucaaagagg aaguccucgc cuacguaguc      960

caacugcccc ucuacggcgu cauugauacc cccugcugga aacuccacac cuccccccuc     1020

ugcaccacaa acaccaaaga agguuccaac aucugccuaa cacgaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccccaag cagaaaccug uaaaguccag     1140

ucuaaccgcg ucuucugcga cacaaugaac ucaagaaccc uaccuuccga aguaaaccuc     1200

ugcaacguag acaucuucaa cccuaaauac gacugcaaaa ucaugacuuc aaaaacagac     1260

guaagcucuu ccguaaucac uucccucggc gccaucguau ccugcuacgg uaaaaccaaa     1320

ugcaccgccu ccaacaaaaa ccgagggauc auaaaaaccu ucuccaacgg cugcgacuac     1380

guaucuaaca aaggcgucga caccgucucc gucggcaaca cccucuauua cguaaacaaa     1440

caagagggca aaucacuaua cgucaaaggc gagccaauca uaaacuucua ugacccacuc     1500

gucuucccuu cagacgaauu ugaugccagc aucagccaag ucaacgaaaa aaucaaccaa     1560

ucacucgccu ucauccgcaa aagcgacgaa cuccuucaca acgucaacgc aggcaaauca     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucguuauccu acucagccuc     1680

aucgcaguug gucuucuccu uuacugcaaa gcccgcucca cccccgucac ccucaguaaa     1740

gaccaacuca gcggaaucaa caacauagca uucuccaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4195
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4195
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4196
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4196
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1620

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4197
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4197
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4198
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4198
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca      900

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc      960

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1020

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1200

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1320

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1620

aaggaccagc ucuccggcau aaacaauauc gcuuucucaa acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4199
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4199
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4200
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4200
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu      900

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga      960

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1020

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1320

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1620

aaggaccagc ucucugggau uaacaauauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4201
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4201
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuaa uacuaaaagc caaugcaaua acaaccauac uaaccgccgu aacauuuugu      120

uucgcaucag gucaaaacau aaccgaagaa uuuuaucaau caacaugcuc agcaguauca      180

aaaggauacu uauccgcucu aagaacagga ugguacacaa guguaauuac aauagagcuc      240

ucaaacauaa aagaaaacaa augcaaugga acugacgcaa aaguuaaacu uauaaaacaa      300

gaacuagaua aauauaaaaa ugcaguaacc gaauuacaac uccuaaugca auccacaccu      360

gcuaccgguu ccggaucagc cauagcaucu ggaguagccg uaugcaaagu ccuccaccua      420

gaaggagaag uaaauaaaau caaaucagca cuauuaucua ccaauaaagc aguugucuca      480

cuauccaaug gcguaucagu acuaacauuc aaaguauuag accuuaaaaa cuacauagac      540

aaacaacuau uaccaauucu gaacaaacaa uccuguucaa uaucaaacau cgaaacggua      600

auagaauuuc aacaaaaaaa uaacagauua cuugaaauaa caagagaauu uucaguaaau      660

gcaggaguua caacacccgu cuccaccuac augcucacaa auucagaauu auuaucacuu      720

auaaacgaca ugccaauaac uaacgaccaa aaaaaacuaa ugucaaacaa uguccaaaua      780

guccgacaac aauccuacuc aauaaugugc auuauaaaag aagaaguccu agccuacguu      840

guccaacuac ccuuauaugg aguaauagau accccaugcu ggaaacuuca uaccuccccc      900

cuaugcacaa caaacacaaa agaaggcuca aacaucugcu uaacacguac agaccgaggu      960

ugguacugug auaacgcagg auccguauca uuuuucccac aagcagaaac augcaaagua     1020

caaucaaacc gcguuuuuug ugacaccaug aacagcagaa cccucccuuc agaaguaaac     1080

cuaugcaacg ucgauauauu uaacccaaaa uacgauugca aaauaaugac aucaaaaacc     1140

gaugucucau cuucaguaau aaccucucua ggagcaauag ucucauguua cggaaaaaca     1200

aaaugcacag caaguaauaa aaauagagga auaauaaaaa cauucucuaa uggcugcgac     1260

uacguaucca auaaaggcgu ugacacagua uccguaggca acacacucua cuauguuaac     1320

aaacaagaag gaaaaaguuu auacguuaaa ggagaaccaa uuauaaacuu uuacgaccca     1380

cucguauucc caucugauga auuugacgca ucaaucucac aaguaaauga aaaaaucaau     1440

cagucccuug ccuuuauaag aaaaucagau gaacuuuuac acaacguuaa cgccggaaaa     1500

ucaacaacca auauaaugau cacaaccaua auaauaguua uaauuguaau uuuauuaucc     1560

uuaauagccg ucggacuacu acuauacugc aaagcaagau cuacacccgu aacccuauca     1620

aaagaccaac uaaguggaau aaauaacauu gcauucucaa auuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4202
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4202
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuaa uacuaaaggc aaacgcaauc acuacaauuc uaaccgccgu gacauucugc      120

uucgccuccg gacaaaacau caccgaagaa uuuuaccaau ccacaugcuc ggccgucagu      180

aaaggcuacc ucucggcucu ccgaaccggc ugguacaccu ccgucaucac caucgaacuc      240

uccaacauca aagaaaacaa augcaacggc accgacgcca aagucaaacu aaucaaacaa      300

gaacucgaca aauacaaaaa cgccgucaca gaacuccaac uacuaaugca aucaacaccc      360

gcuacaggaa gcggcuccgc caucgccagc ggcguagcug ucugcaaagu ccuccaccuc      420

gaaggugaag ucaacaaaau caaaucagcc cuacucagca caaacaaagc cguuguaagc      480

cuauccaacg gcgucuccgu acuaacauuc aaaguccuug accucaagaa cuacaucgac      540

aaacaacuuc ucccaauccu aaacaaacaa agcugcucaa uuuccaacau cgaaacagua      600

aucgaauuuc aacaaaaaaa caaccgacuc cucgaaauca cccgcgaauu uuccguuaac      660

gccggcguua caacccccgu cuccaccuac augcucacca auuccgaacu acuaucacuc      720

auaaacgaca ugccuaucac aaacgaccaa aaaaaacuaa ugucaaacaa uguccaaauc      780

guccgccagc aaagcuauuc caucaugugc aucaucaaag aggaaguccu cgccuacgua      840

guccaacugc cccucuacgg cgucauugau acccccugcu ggaaacucca caccuccccc      900

cucugcacca caaacaccaa agaagguucc aacaucugcc uaacacgaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgucucc uucuuccccc aagcagaaac cuguaaaguc     1020

cagucuaacc gcgucuucug cgacacaaug aacucaagaa cccuaccuuc cgaaguaaac     1080

cucugcaacg uagacaucuu caacccuaaa uacgacugca aaaucaugac uucaaaaaca     1140

gacguaagcu cuuccguaau cacuucccuc ggcgccaucg uauccugcua cgguaaaacc     1200

aaaugcaccg ccuccaacaa aaaccgaggg aucauaaaaa ccuucuccaa cggcugcgac     1260

uacguaucua acaaaggcgu cgacaccguc uccgucggca acacccucua uuacguaaac     1320

aaacaagagg gcaaaucacu auacgucaaa ggcgagccaa ucauaaacuu cuaugaccca     1380

cucgucuucc cuucagacga auuugaugcc agcaucagcc aagucaacga aaaaaucaac     1440

caaucacucg ccuucauccg caaaagcgac gaacuccuuc acaacgucaa cgcaggcaaa     1500

ucaaccacca acaucaugau caccaccauc aucaucguca ucaucguuau ccuacucagc     1560

cucaucgcag uuggucuucu ccuuuacugc aaagcccgcu ccacccccgu cacccucagu     1620

aaagaccaac ucagcggaau caacaacaua gcauucucca acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4203
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4203
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc cuguccaagg     1620

accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4204
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4204
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug caccucgagg      420

gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug gucucccuca      480

gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac cggggguggu      960

acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag gucaaccugu     1080

gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg aagaccaagu     1200

gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg ugcgacuacg     1260

ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac gucaacaagc     1320

aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc gggaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc cugagcaagg     1620

accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4205
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4205
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac gucaacaagc     1320

aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc cucuccaagg     1620

accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4206
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4206
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug caccucgagg      420

gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug gucucucuca      480

gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac auugauaaac      540

aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu gucaacgcgg      660

gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug agccucauca      720

acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc cagaucguuc      780

gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca uauguagugc      840

aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca agcccacugu      900

guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau cguggcuggu      960

acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc aagguucagu     1020

caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag gucaaccucu     1080

gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc aaaacagacg     1140

uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu aagacuaaau     1200

gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg ugugauuaug     1260

ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau guuaacaagc     1320

aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau gacccuuugg     1380

uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa aucaaccaga     1440

gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg ggaaagucaa     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaagucuca     1560

ucgccgucgg ccugcuuuug uacugcaaag cacgcucuac accggugacc cugagcaagg     1620

accagcucuc cggcauaaac aauaucgcuu ucucaaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4207
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4207
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc cugagcaagg     1620

accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4208
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4208
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc caccuggagg      420

gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc gugucccuca      480

gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac auugauaaac      540

aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc gugaacgccg      660

gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc ucucugauca      720

acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug cagaucguga      780

gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu uaugugguuc      840

aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg ucuccucucu      900

guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau cgcggauggu      960

acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc aaggugcaga     1020

gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag gugaaucucu     1080

gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc aaaacagacg     1140

uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga aagacaaaau     1200

gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg ugugauuaug     1260

uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau guuaacaagc     1320

aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau gacccucucg     1380

ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa auuaaccaga     1440

gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc ggaaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucucuga     1560

ucgccguggg ccuccugcug uacugcaaag cuagauccac accugugacc cuuagcaagg     1620

accagcucuc ugggauuaac aauaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4209
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4209
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacuaauacu aaaagccaau gcaauaacaa ccauacuaac cgccguaaca uuuuguuucg      120

caucagguca aaacauaacc gaagaauuuu aucaaucaac augcucagca guaucaaaag      180

gauacuuauc cgcucuaaga acaggauggu acacaagugu aauuacaaua gagcucucaa      240

acauaaaaga aaacaaaugc aauggaacug acgcaaaagu uaaacuuaua aaacaagaac      300

uagauaaaua uaaaaaugca guaaccgaau uacaacuccu aaugcaaucc acaccugcua      360

ccgguuccgg aucagccaua gcaucuggag uagccguaug caaaguccuc caccuagaag      420

gagaaguaaa uaaaaucaaa ucagcacuau uaucuaccaa uaaagcaguu gucucacuau      480

ccaauggcgu aucaguacua acauucaaag uauuagaccu uaaaaacuac auagacaaac      540

aacuauuacc aauucugaac aaacaauccu guucaauauc aaacaucgaa acgguaauag      600

aauuucaaca aaaaaauaac agauuacuug aaauaacaag agaauuuuca guaaaugcag      660

gaguuacaac acccgucucc accuacaugc ucacaaauuc agaauuauua ucacuuauaa      720

acgacaugcc aauaacuaac gaccaaaaaa aacuaauguc aaacaauguc caaauagucc      780

gacaacaauc cuacucaaua augugcauua uaaaagaaga aguccuagcc uacguugucc      840

aacuacccuu auauggagua auagauaccc caugcuggaa acuucauacc uccccccuau      900

gcacaacaaa cacaaaagaa ggcucaaaca ucugcuuaac acguacagac cgagguuggu      960

acugugauaa cgcaggaucc guaucauuuu ucccacaagc agaaacaugc aaaguacaau     1020

caaaccgcgu uuuuugugac accaugaaca gcagaacccu cccuucagaa guaaaccuau     1080

gcaacgucga uauauuuaac ccaaaauacg auugcaaaau aaugacauca aaaaccgaug     1140

ucucaucuuc aguaauaacc ucucuaggag caauagucuc auguuacgga aaaacaaaau     1200

gcacagcaag uaauaaaaau agaggaauaa uaaaaacauu cucuaauggc ugcgacuacg     1260

uauccaauaa aggcguugac acaguauccg uaggcaacac acucuacuau guuaacaaac     1320

aagaaggaaa aaguuuauac guuaaaggag aaccaauuau aaacuuuuac gacccacucg     1380

uauucccauc ugaugaauuu gacgcaucaa ucucacaagu aaaugaaaaa aucaaucagu     1440

cccuugccuu uauaagaaaa ucagaugaac uuuuacacaa cguuaacgcc ggaaaaucaa     1500

caaccaauau aaugaucaca accauaauaa uaguuauaau uguaauuuua uuauccuuaa     1560

uagccgucgg acuacuacua uacugcaaag caagaucuac acccguaacc cuaucaaaag     1620

accaacuaag uggaauaaau aacauugcau ucucaaauua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4210
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4210
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccuaauacu aaaggcaaac gcaaucacua caauucuaac cgccgugaca uucugcuucg      120

ccuccggaca aaacaucacc gaagaauuuu accaauccac augcucggcc gucaguaaag      180

gcuaccucuc ggcucuccga accggcuggu acaccuccgu caucaccauc gaacucucca      240

acaucaaaga aaacaaaugc aacggcaccg acgccaaagu caaacuaauc aaacaagaac      300

ucgacaaaua caaaaacgcc gucacagaac uccaacuacu aaugcaauca acacccgcua      360

caggaagcgg cuccgccauc gccagcggcg uagcugucug caaaguccuc caccucgaag      420

gugaagucaa caaaaucaaa ucagcccuac ucagcacaaa caaagccguu guaagccuau      480

ccaacggcgu cuccguacua acauucaaag uccuugaccu caagaacuac aucgacaaac      540

aacuucuccc aauccuaaac aaacaaagcu gcucaauuuc caacaucgaa acaguaaucg      600

aauuucaaca aaaaaacaac cgacuccucg aaaucacccg cgaauuuucc guuaacgccg      660

gcguuacaac ccccgucucc accuacaugc ucaccaauuc cgaacuacua ucacucauaa      720

acgacaugcc uaucacaaac gaccaaaaaa aacuaauguc aaacaauguc caaaucgucc      780

gccagcaaag cuauuccauc augugcauca ucaaagagga aguccucgcc uacguagucc      840

aacugccccu cuacggcguc auugauaccc ccugcuggaa acuccacacc uccccccucu      900

gcaccacaaa caccaaagaa gguuccaaca ucugccuaac acgaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccccaagc agaaaccugu aaaguccagu     1020

cuaaccgcgu cuucugcgac acaaugaacu caagaacccu accuuccgaa guaaaccucu     1080

gcaacguaga caucuucaac ccuaaauacg acugcaaaau caugacuuca aaaacagacg     1140

uaagcucuuc cguaaucacu ucccucggcg ccaucguauc cugcuacggu aaaaccaaau     1200

gcaccgccuc caacaaaaac cgagggauca uaaaaaccuu cuccaacggc ugcgacuacg     1260

uaucuaacaa aggcgucgac accgucuccg ucggcaacac ccucuauuac guaaacaaac     1320

aagagggcaa aucacuauac gucaaaggcg agccaaucau aaacuucuau gacccacucg     1380

ucuucccuuc agacgaauuu gaugccagca ucagccaagu caacgaaaaa aucaaccaau     1440

cacucgccuu cauccgcaaa agcgacgaac uccuucacaa cgucaacgca ggcaaaucaa     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cguuauccua cucagccuca     1560

ucgcaguugg ucuucuccuu uacugcaaag cccgcuccac ccccgucacc cucaguaaag     1620

accaacucag cggaaucaac aacauagcau ucuccaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4211
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1) R7454

<400>  4211
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

agcaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccggacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccggagc     1560

acgcccguca cccuguccaa ggaccagcug agcggcauca acaacaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4212
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt1)

<400>  4212
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccggcagc ggguccgcca ucgccagcgg cguggcggug      360

ugcaaggucc ugcaccucga gggcgaggug aacaagauca aguccgcccu gcugagcacc      420

aacaaggccg uggucucccu cagcaacggg guguccgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcagag cugcuccauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggcgucacc acgcccguga gcaccuacau gcucaccaac      660

agcgagcugc ugucccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccc cuguacgggg ugaucgacac gccgugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggcuccaa caucugccug      900

acccgcaccg accgggggug guacugcgac aacgcgggcu ccgugagcuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccggacc     1020

cuccccuccg aggucaaccu gugcaacgug gacaucuuca acccgaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg cgccaucgug     1140

uccugcuacg ggaagaccaa gugcaccgcc agcaacaaga accggggcau caucaagacc     1200

uucuccaacg ggugcgacua cgugagcaac aagggcgucg acacggugag cgugggcaac     1260

acccucuacu acgucaacaa gcaggagggg aagucccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcg uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg ccgggaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug ggccuccugc uguacugcaa ggcccggucc     1560

accccgguga cccugagcaa ggaccagcuc uccgggauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4213
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt2)

<400>  4213
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

uccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccgcacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu acgucaacaa gcaggagggc aagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcucc     1560

acccccguca cccucuccaa ggaccagcuc uccggcauca acaacaucgc cuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4214
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt3)

<400>  4214
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccggcucg gggucagcua uagcaagcgg aguggccguc      360

uguaaggugu ugcaccucga gggcgaaguu aacaaaauca agagugcucu gcuguccacg      420

aauaaagccg uggucucucu cagcaacggu guguccguau uaacuuuuaa gguucuggac      480

cuuaagaauu acauugauaa acaauugcug ccuauccuaa acaagcaguc augcaguauu      540

agcaauaucg agaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuuu cugucaacgc gggggugacu accccagugu ccacauauau gcuuaccaau      660

ucagaacugu ugagccucau caacgacaug ccgauuacga acgaucaaaa gaaacugaug      720

aguaauaacg uccagaucgu ucgccagcag ucuuacucca ucauguguau uauaaaggag      780

gaaguguuag cauauguagu gcaacugccc cucuacggag ucaucgacac uccuugcugg      840

aaacuucaua caagcccacu guguaccacu aauacaaagg agggcucgaa cauuugcuug      900

acccgaacgg aucguggcug guacugugac aaugccgggu cuguguccuu cuuuccccag      960

gcugaaaccu gcaagguuca gucaaacaga guguucugug auacaaugaa uaguagaacu     1020

cugccuagcg aggucaaccu cugcaaugug gacaucuuua acccaaaaua ugauugcaag     1080

auaaugaccu ccaaaacaga cguaucuagc ucaguuauua ccagucuggg agccaucgug     1140

uccuguuacg guaagacuaa augcacagca agcaauaaga acaggggcau cauuaagacc     1200

uucucuaaug ggugugauua ugucucaaac aaaggagugg acacugucag ugugggcaau     1260

acgcuuuacu auguuaacaa gcaagagggu aaaagccugu acgugaaggg ggaacccauc     1320

auuaacuuuu augacccuuu gguauuccca uccgaugagu uugacgcuuc uauaucgcag     1380

gucaaugaga aaaucaacca gagccucgcc uucauucgga aguccgauga acuguuacac     1440

aaugugaacg cgggaaaguc aacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaagucu caucgccguc ggccugcuuu uguacugcaa agcacgcucu     1560

acaccgguga cccugagcaa ggaccagcuc uccggcauaa acaauaucgc uuucucaaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4215
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt4)

<400>  4215
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagcagaacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagaagc     1560

acccccguga cccugagcaa ggaccagcug agcggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4216
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt5)

<400>  4216
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacagggucu ggaagcgcua uugccuccgg cgucgcggug      360

uguaagguuc uccaccugga gggggaagug aacaaaauca agagcgcccu ucugucuacc      420

aauaaagcug ucgugucccu cagcaacgga guuucugugc ugacauuuaa gguccuugac      480

cugaagaauu acauugauaa acaacuccug ccuauccuga acaagcaguc cugcagcauu      540

ucuaauaucg agaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuuu ccgugaacgc cggcgucaca accccgguua gcacauauau gcuuaccaau      660

uccgaacugc ucucucugau caacgacaug cccauuacca acgaucaaaa gaaacuuaug      720

agcaauaacg ugcagaucgu gagacagcag uccuacagca uuauguguau cauuaaggag      780

gaaguccugg cuuauguggu ucaacucccu cuguacggcg ugaucgacac acccugcugg      840

aaacugcaua cgucuccucu cuguaccaca aauaccaagg agggguccaa caucugccug      900

acacggaccg aucgcggaug guacugugac aaugccggca gcgucucuuu cuuuccccag      960

gcggaaacgu gcaaggugca gagcaacaga guuuucugug auacaaugaa cuccagaacc     1020

cugccuucug aggugaaucu cugcaauguc gacauuuuua acccgaaaua ugauugcaag     1080

aucaugacca gcaaaacaga cguguccagc ucugucauua ccucccuggg ggccaucgug     1140

agcuguuacg gaaagacaaa augcacggcu ucuaauaaga accggggcau uaucaagacc     1200

uucuccaaug ggugugauua uguuagcaac aaaggagugg acacagucuc cgugggcaau     1260

acccuuuacu auguuaacaa gcaagagggc aaaucucugu acgugaaggg ggaacccauc     1320

auuaacuuuu augacccucu cgucuucccc agcgaugagu uugacgccuc caucucucag     1380

gugaaugaga aaauuaacca gagccuggcu uucauccgca aguccgauga acugcuccac     1440

aaugugaacg ccggaaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucucu gaucgccgug ggccuccugc uguacugcaa agcuagaucc     1560

acaccuguga cccuuagcaa ggaccagcuc ucugggauua acaauaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4217
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt6)

<400>  4217
gggagaaagc uuaccaugga acuacuaaua cuaaaagcca augcaauaac aaccauacua       60

accgccguaa cauuuuguuu cgcaucaggu caaaacauaa ccgaagaauu uuaucaauca      120

acaugcucag caguaucaaa aggauacuua uccgcucuaa gaacaggaug guacacaagu      180

guaauuacaa uagagcucuc aaacauaaaa gaaaacaaau gcaauggaac ugacgcaaaa      240

guuaaacuua uaaaacaaga acuagauaaa uauaaaaaug caguaaccga auuacaacuc      300

cuaaugcaau ccacaccugc uaccgguucc ggaucagcca uagcaucugg aguagccgua      360

ugcaaagucc uccaccuaga aggagaagua aauaaaauca aaucagcacu auuaucuacc      420

aauaaagcag uugucucacu auccaauggc guaucaguac uaacauucaa aguauuagac      480

cuuaaaaacu acauagacaa acaacuauua ccaauucuga acaaacaauc cuguucaaua      540

ucaaacaucg aaacgguaau agaauuucaa caaaaaaaua acagauuacu ugaaauaaca      600

agagaauuuu caguaaaugc aggaguuaca acacccgucu ccaccuacau gcucacaaau      660

ucagaauuau uaucacuuau aaacgacaug ccaauaacua acgaccaaaa aaaacuaaug      720

ucaaacaaug uccaaauagu ccgacaacaa uccuacucaa uaaugugcau uauaaaagaa      780

gaaguccuag ccuacguugu ccaacuaccc uuauauggag uaauagauac cccaugcugg      840

aaacuucaua ccuccccccu augcacaaca aacacaaaag aaggcucaaa caucugcuua      900

acacguacag accgagguug guacugugau aacgcaggau ccguaucauu uuucccacaa      960

gcagaaacau gcaaaguaca aucaaaccgc guuuuuugug acaccaugaa cagcagaacc     1020

cucccuucag aaguaaaccu augcaacguc gauauauuua acccaaaaua cgauugcaaa     1080

auaaugacau caaaaaccga ugucucaucu ucaguaauaa ccucucuagg agcaauaguc     1140

ucauguuacg gaaaaacaaa augcacagca aguaauaaaa auagaggaau aauaaaaaca     1200

uucucuaaug gcugcgacua cguauccaau aaaggcguug acacaguauc cguaggcaac     1260

acacucuacu auguuaacaa acaagaagga aaaaguuuau acguuaaagg agaaccaauu     1320

auaaacuuuu acgacccacu cguauuccca ucugaugaau uugacgcauc aaucucacaa     1380

guaaaugaaa aaaucaauca gucccuugcc uuuauaagaa aaucagauga acuuuuacac     1440

aacguuaacg ccggaaaauc aacaaccaau auaaugauca caaccauaau aauaguuaua     1500

auuguaauuu uauuauccuu aauagccguc ggacuacuac uauacugcaa agcaagaucu     1560

acacccguaa cccuaucaaa agaccaacua aguggaauaa auaacauugc auucucaaau     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4218
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut0 (opt11)

<400>  4218
gggagaaagc uuaccaugga acuccuaaua cuaaaggcaa acgcaaucac uacaauucua       60

accgccguga cauucugcuu cgccuccgga caaaacauca ccgaagaauu uuaccaaucc      120

acaugcucgg ccgucaguaa aggcuaccuc ucggcucucc gaaccggcug guacaccucc      180

gucaucacca ucgaacucuc caacaucaaa gaaaacaaau gcaacggcac cgacgccaaa      240

gucaaacuaa ucaaacaaga acucgacaaa uacaaaaacg ccgucacaga acuccaacua      300

cuaaugcaau caacacccgc uacaggaagc ggcuccgcca ucgccagcgg cguagcuguc      360

ugcaaagucc uccaccucga aggugaaguc aacaaaauca aaucagcccu acucagcaca      420

aacaaagccg uuguaagccu auccaacggc gucuccguac uaacauucaa aguccuugac      480

cucaagaacu acaucgacaa acaacuucuc ccaauccuaa acaaacaaag cugcucaauu      540

uccaacaucg aaacaguaau cgaauuucaa caaaaaaaca accgacuccu cgaaaucacc      600

cgcgaauuuu ccguuaacgc cggcguuaca acccccgucu ccaccuacau gcucaccaau      660

uccgaacuac uaucacucau aaacgacaug ccuaucacaa acgaccaaaa aaaacuaaug      720

ucaaacaaug uccaaaucgu ccgccagcaa agcuauucca ucaugugcau caucaaagag      780

gaaguccucg ccuacguagu ccaacugccc cucuacggcg ucauugauac ccccugcugg      840

aaacuccaca ccuccccccu cugcaccaca aacaccaaag aagguuccaa caucugccua      900

acacgaaccg acagaggcug guacugcgac aacgccggca gcgucuccuu cuucccccaa      960

gcagaaaccu guaaagucca gucuaaccgc gucuucugcg acacaaugaa cucaagaacc     1020

cuaccuuccg aaguaaaccu cugcaacgua gacaucuuca acccuaaaua cgacugcaaa     1080

aucaugacuu caaaaacaga cguaagcucu uccguaauca cuucccucgg cgccaucgua     1140

uccugcuacg guaaaaccaa augcaccgcc uccaacaaaa accgagggau cauaaaaacc     1200

uucuccaacg gcugcgacua cguaucuaac aaaggcgucg acaccgucuc cgucggcaac     1260

acccucuauu acguaaacaa acaagagggc aaaucacuau acgucaaagg cgagccaauc     1320

auaaacuucu augacccacu cgucuucccu ucagacgaau uugaugccag caucagccaa     1380

gucaacgaaa aaaucaacca aucacucgcc uucauccgca aaagcgacga acuccuucac     1440

aacgucaacg caggcaaauc aaccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucguuaucc uacucagccu caucgcaguu ggucuucucc uuuacugcaa agcccgcucc     1560

acccccguca cccucaguaa agaccaacuc agcggaauca acaacauagc auucuccaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4219
<211>  514
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4219

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Ser 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Arg Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Tyr Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg 
        


<210>  4220
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4220
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc gguga                     1545


<210>  4221
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4221
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccaccg gcagcggguc cgccaucgcc agcggcgugg cggugugcaa gguccugcac      360

cucgagggcg aggugaacaa gaucaagucc gcccugcuga gcaccaacaa ggccgugguc      420

ucccucagca acgggguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccccugua cggggugauc gacacgccgu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      900

gggugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1020

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1140

accaagugca ccgccagcaa caagaaccgg ggcaucauca agaccuucuc caacgggugc     1200

gacuacguga gcaacaaggg cgucgacacg gugagcgugg gcaacacccu cuacuacguc     1260

aacaagcagg aggggaaguc ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguga                     1545


<210>  4222
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4222
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1260

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuga                     1545


<210>  4223
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4223
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccaccg gcucgggguc agcuauagca agcggagugg ccgucuguaa gguguugcac      360

cucgagggcg aaguuaacaa aaucaagagu gcucugcugu ccacgaauaa agccgugguc      420

ucucucagca acgguguguc cguauuaacu uuuaagguuc uggaccuuaa gaauuacauu      480

gauaaacaau ugcugccuau ccuaaacaag cagucaugca guauuagcaa uaucgagacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuucuguc      600

aacgcggggg ugacuacccc aguguccaca uauaugcuua ccaauucaga acuguugagc      660

cucaucaacg acaugccgau uacgaacgau caaaagaaac ugaugaguaa uaacguccag      720

aucguucgcc agcagucuua cuccaucaug uguauuauaa aggaggaagu guuagcauau      780

guagugcaac ugccccucua cggagucauc gacacuccuu gcuggaaacu ucauacaagc      840

ccacugugua ccacuaauac aaaggagggc ucgaacauuu gcuugacccg aacggaucgu      900

ggcugguacu gugacaaugc cgggucugug uccuucuuuc cccaggcuga aaccugcaag      960

guucagucaa acagaguguu cugugauaca augaauagua gaacucugcc uagcgagguc     1020

aaccucugca auguggacau cuuuaaccca aaauaugauu gcaagauaau gaccuccaaa     1080

acagacguau cuagcucagu uauuaccagu cugggagcca ucguguccug uuacgguaag     1140

acuaaaugca cagcaagcaa uaagaacagg ggcaucauua agaccuucuc uaaugggugu     1200

gauuaugucu caaacaaagg aguggacacu gucagugugg gcaauacgcu uuacuauguu     1260

aacaagcaag aggguaaaag ccuguacgug aagggggaac ccaucauuaa cuuuuaugac     1320

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa ugagaaaauc     1380

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcggga     1440

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcuga                     1545


<210>  4224
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4224
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gauga                     1545


<210>  4225
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4225
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacag ggucuggaag cgcuauugcc uccggcgucg cgguguguaa gguucuccac      360

cuggaggggg aagugaacaa aaucaagagc gcccuucugu cuaccaauaa agcugucgug      420

ucccucagca acggaguuuc ugugcugaca uuuaaggucc uugaccugaa gaauuacauu      480

gauaaacaac uccugccuau ccugaacaag caguccugca gcauuucuaa uaucgagacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuuccgug      600

aacgccggcg ucacaacccc gguuagcaca uauaugcuua ccaauuccga acugcucucu      660

cugaucaacg acaugcccau uaccaacgau caaaagaaac uuaugagcaa uaacgugcag      720

aucgugagac agcaguccua cagcauuaug uguaucauua aggaggaagu ccuggcuuau      780

gugguucaac ucccucugua cggcgugauc gacacacccu gcuggaaacu gcauacgucu      840

ccucucugua ccacaaauac caaggagggg uccaacaucu gccugacacg gaccgaucgc      900

ggaugguacu gugacaaugc cggcagcguc ucuuucuuuc cccaggcgga aacgugcaag      960

gugcagagca acagaguuuu cugugauaca augaacucca gaacccugcc uucugaggug     1020

aaucucugca augucgacau uuuuaacccg aaauaugauu gcaagaucau gaccagcaaa     1080

acagacgugu ccagcucugu cauuaccucc cugggggcca ucgugagcug uuacggaaag     1140

acaaaaugca cggcuucuaa uaagaaccgg ggcauuauca agaccuucuc caaugggugu     1200

gauuauguua gcaacaaagg aguggacaca gucuccgugg gcaauacccu uuacuauguu     1260

aacaagcaag agggcaaauc ucuguacgug aagggggaac ccaucauuaa cuuuuaugac     1320

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa ugagaaaauu     1380

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccgga     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucucugaucg ccgugggccu ccugcuguac ugcaaagcua gauga                     1545


<210>  4226
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4226
auggaauuac ucauccucaa agcaaacgca auaacaacaa uacuaacagc agucacuuuc       60

ugcuucgcau ccggacaaaa uaucacagaa gaauuuuacc aauccaccug cucugcuguc      120

uccaaaggau accuaucugc ccucagaacc gguugguaua caucugucau aaccauagaa      180

cuaucaaaca uuaaagaaaa caaauguaac ggaacagacg caaaagucaa acuuauaaaa      240

caagaauuag acaaauacaa aaacgcaguc acagaauuac aacuacuaau gcaaucaacc      300

ccagcaaccg gaucaggauc cgcaauagcu ucaggaguag caguauguaa aguucuacac      360

uuagaaggag aagucaacaa aauuaaaucc gcacuauuau caaccaacaa agcagucgua      420

ucuuuaucaa acggaguauc uguacuuaca uucaaaguac uagaccuaaa aaauuacauu      480

gauaaacaau uacuaccaau acuaaacaaa caaucauguu ccaucucuaa cauagaaaca      540

guaauagaau uucaacaaaa aaauaacaga uuacuugaaa ucacccgaga auuuucagua      600

aacgcaggag uaaccacacc cguaucuaca uacaugcuaa caaacucuga acuucugagc      660

cuaauaaaug acaugccaau aaccaacgac caaaaaaaac uaauguccaa caacguacaa      720

auaguacgac aacaaucuua cucaaucaug ugcauaauca aagaagaagu acuagcuuau      780

guaguccaac uuccacucua cggaguaaua gacacccccu gcuggaaacu acacacauca      840

ccacuaugca caacaaacac aaaagaaggc ucaaacauau gccuaacaag aacugacaga      900

ggaugguauu gugacaaugc aggcucuguc ucauucuuuc cacaagccga aacaugcaaa      960

guucaaucaa accgaguuuu cugugacaca augaacucua gaacucuccc aucagaaguc     1020

aacuuaugca acguugacau auucaaccca aaauaugacu guaaaauaau gacuuccaaa     1080

acugauguau cauccuccgu cauaacaucc cuaggagcua uuguaucaug uuacgggaaa     1140

accaaaugca cagccucaaa caaaaaccgc gguaucauaa aaacauuuuc aaacggaugu     1200

gauuacguaa gcaauaaagg aguagacacc guaucaguag gaaauacacu auacuaugua     1260

aauaaacaag aaggaaaauc acuauauguc aaaggagaac caaucauaaa uuucuaugac     1320

ccacuuguau ucccauccga ugaauuugac gcaagcauuu cacaggucaa cgaaaaaaua     1380

aaccaaucac uagccuucau cagaaaauca gacgaacuac uacauaacgu aaacgccgga     1440

aaaucaacaa ccaacauaau gauaacaaca aucauaauag uuaucauagu aauacuacua     1500

ucucuaauag cugucggacu cuuacuauau ugcaaagccc gauaa                     1545


<210>  4227
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut0

<400>  4227
auggaacuac uaauccugaa agccaacgcc auaaccacaa uccuuaccgc agucaccuuc       60

ugcuucgccu ccggucaaaa caucacagaa gaguucuacc aauccaccug uuccgcaguc      120

agcaaaggcu accucuccgc acuccgaacc ggaugguaca ccagcgucau caccaucgaa      180

cuauccaaca uaaaggaaaa uaagugcaau gguacagaug ccaaggucaa acucauaaag      240

caagaacucg acaaauacaa aaacgccguc accgaacuac aacuacuaau gcaaucuacc      300

cccgcaacag gcucagguuc cgccauagcc uccggcgucg ccguuugcaa aguccuccac      360

cucgaaggcg aaguaaacaa aaucaaaucc gcccuacucu caaccaacaa agcagucguc      420

ucccucucaa acggagucuc gguccucacc uucaaagucc ucgaccucaa aaacuauaua      480

gacaaacaac uccuacccau acucaacaaa caguccugca gcauauccaa caucgaaacc      540

gugaucgagu uccaacagaa aaacaacaga cuccucgaaa ucacucgaga guucuccgua      600

aacgccggcg ucacaacccc agucucaaca uacaugcuca ccaacagcga acuccuauca      660

cuaaucaacg acaugccuau cacaaaugau cagaagaaac uaaugagcaa caacguccaa      720

aucguccgcc aacaaucaua cuccaucaug ugcaucauaa aagaagaagu ccuagccuac      780

gugguccagc uaccccucua cggcguaauu gacaccccuu gcuggaaacu acacacuuca      840

ccccucugca caaccaacac caaagaaggu ucaaacaucu gccucacacg aacagaccgc      900

ggcugguacu gcgacaacgc cggauccgua uccuucuucc cccaagcaga aaccugcaaa      960

guucaaucca accggguauu cugcgacacc augaacucaa gaacccuucc cuccgaagua     1020

aaucuaugca acgucgacau auucaaccca aaauacgacu gcaaaaucau gaccuccaaa     1080

accgaugucu ccagcagcgu caucaccagc cucggcgcca ucgucuccug cuacggcaaa     1140

acaaaaugua cagcauccaa caaaaaccga ggcauaauca aaaccuucuc caacgggugc     1200

gauuacguca gcaacaaagg cgucgacacc gucuccgugg gcaacacccu auacuacguc     1260

aacaaacaag aaggcaaauc acuguacgua aagggcgaac ccaucaucaa cuucuaugac     1320

ccucuggugu ucccauccga ugaauuugac gcauccauau cucaggucaa cgaaaagauc     1380

aaccaauccc ucgccuucau acgcaaaucc gacgaacucc uacacaacgu caacgcuggu     1440

aaaagcacca ccaacaucau gaucaccaca aucaucaucg ucauaaucgu uauccuacuc     1500

ucccuuauag cagucggacu ccuccucuac ugcaaagccc gcuaa                     1545


<210>  4228
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4228
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4229
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4229
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4230
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4230
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4231
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4231
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4232
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4232
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4233
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4233
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4234
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4234
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uccucaaagc aaacgcaaua acaacaauac      120

uaacagcagu cacuuucugc uucgcauccg gacaaaauau cacagaagaa uuuuaccaau      180

ccaccugcuc ugcugucucc aaaggauacc uaucugcccu cagaaccggu ugguauacau      240

cugucauaac cauagaacua ucaaacauua aagaaaacaa auguaacgga acagacgcaa      300

aagucaaacu uauaaaacaa gaauuagaca aauacaaaaa cgcagucaca gaauuacaac      360

uacuaaugca aucaacccca gcaaccggau caggauccgc aauagcuuca ggaguagcag      420

uauguaaagu ucuacacuua gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa      480

ccaacaaagc agucguaucu uuaucaaacg gaguaucugu acuuacauuc aaaguacuag      540

accuaaaaaa uuacauugau aaacaauuac uaccaauacu aaacaaacaa ucauguucca      600

ucucuaacau agaaacagua auagaauuuc aacaaaaaaa uaacagauua cuugaaauca      660

cccgagaauu uucaguaaac gcaggaguaa ccacacccgu aucuacauac augcuaacaa      720

acucugaacu ucugagccua auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaaua guacgacaac aaucuuacuc aaucaugugc auaaucaaag      840

aagaaguacu agcuuaugua guccaacuuc cacucuacgg aguaauagac acccccugcu      900

ggaaacuaca cacaucacca cuaugcacaa caaacacaaa agaaggcuca aacauaugcc      960

uaacaagaac ugacagagga ugguauugug acaaugcagg cucugucuca uucuuuccac     1020

aagccgaaac augcaaaguu caaucaaacc gaguuuucug ugacacaaug aacucuagaa     1080

cucucccauc agaagucaac uuaugcaacg uugacauauu caacccaaaa uaugacugua     1140

aaauaaugac uuccaaaacu gauguaucau ccuccgucau aacaucccua ggagcuauug     1200

uaucauguua cgggaaaacc aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa     1260

cauuuucaaa cggaugugau uacguaagca auaaaggagu agacaccgua ucaguaggaa     1320

auacacuaua cuauguaaau aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa     1380

ucauaaauuu cuaugaccca cuuguauucc cauccgauga auuugacgca agcauuucac     1440

aggucaacga aaaaauaaac caaucacuag ccuucaucag aaaaucagac gaacuacuac     1500

auaacguaaa cgccggaaaa ucaacaacca acauaaugau aacaacaauc auaauaguua     1560

ucauaguaau acuacuaucu cuaauagcug ucggacucuu acuauauugc aaagcccgau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4235
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4235
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccugaaagc caacgccaua accacaaucc      120

uuaccgcagu caccuucugc uucgccuccg gucaaaacau cacagaagag uucuaccaau      180

ccaccuguuc cgcagucagc aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca      240

gcgucaucac caucgaacua uccaacauaa aggaaaauaa gugcaauggu acagaugcca      300

aggucaaacu cauaaagcaa gaacucgaca aauacaaaaa cgccgucacc gaacuacaac      360

uacuaaugca aucuaccccc gcaacaggcu cagguuccgc cauagccucc ggcgucgccg      420

uuugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc agucgucucc cucucaaacg gagucucggu ccucaccuuc aaaguccucg      540

accucaaaaa cuauauagac aaacaacucc uacccauacu caacaaacag uccugcagca      600

uauccaacau cgaaaccgug aucgaguucc aacagaaaaa caacagacuc cucgaaauca      660

cucgagaguu cuccguaaac gccggcguca caaccccagu cucaacauac augcucacca      720

acagcgaacu ccuaucacua aucaacgaca ugccuaucac aaaugaucag aagaaacuaa      780

ugagcaacaa cguccaaauc guccgccaac aaucauacuc caucaugugc aucauaaaag      840

aagaaguccu agccuacgug guccagcuac cccucuacgg cguaauugac accccuugcu      900

ggaaacuaca cacuucaccc cucugcacaa ccaacaccaa agaagguuca aacaucugcc      960

ucacacgaac agaccgcggc ugguacugcg acaacgccgg auccguaucc uucuuccccc     1020

aagcagaaac cugcaaaguu caauccaacc ggguauucug cgacaccaug aacucaagaa     1080

cccuucccuc cgaaguaaau cuaugcaacg ucgacauauu caacccaaaa uacgacugca     1140

aaaucaugac cuccaaaacc gaugucucca gcagcgucau caccagccuc ggcgccaucg     1200

ucuccugcua cggcaaaaca aaauguacag cauccaacaa aaaccgaggc auaaucaaaa     1260

ccuucuccaa cgggugcgau uacgucagca acaaaggcgu cgacaccguc uccgugggca     1320

acacccuaua cuacgucaac aaacaagaag gcaaaucacu guacguaaag ggcgaaccca     1380

ucaucaacuu cuaugacccu cugguguucc cauccgauga auuugacgca uccauaucuc     1440

aggucaacga aaagaucaac caaucccucg ccuucauacg caaauccgac gaacuccuac     1500

acaacgucaa cgcugguaaa agcaccacca acaucaugau caccacaauc aucaucguca     1560

uaaucguuau ccuacucucc cuuauagcag ucggacuccu ccucuacugc aaagcccgcu     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4236
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4236
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4237
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4237
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4238
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4238
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4239
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4239
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4240
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4240
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4241
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4241
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4242
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4242
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau ccucaaagca      120

aacgcaauaa caacaauacu aacagcaguc acuuucugcu ucgcauccgg acaaaauauc      180

acagaagaau uuuaccaauc caccugcucu gcugucucca aaggauaccu aucugcccuc      240

agaaccgguu gguauacauc ugucauaacc auagaacuau caaacauuaa agaaaacaaa      300

uguaacggaa cagacgcaaa agucaaacuu auaaaacaag aauuagacaa auacaaaaac      360

gcagucacag aauuacaacu acuaaugcaa ucaaccccag caaccggauc aggauccgca      420

auagcuucag gaguagcagu auguaaaguu cuacacuuag aaggagaagu caacaaaauu      480

aaauccgcac uauuaucaac caacaaagca gucguaucuu uaucaaacgg aguaucugua      540

cuuacauuca aaguacuaga ccuaaaaaau uacauugaua aacaauuacu accaauacua      600

aacaaacaau cauguuccau cucuaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaaucac ccgagaauuu ucaguaaacg caggaguaac cacacccgua      720

ucuacauaca ugcuaacaaa cucugaacuu cugagccuaa uaaaugacau gccaauaacc      780

aacgaccaaa aaaaacuaau guccaacaac guacaaauag uacgacaaca aucuuacuca      840

aucaugugca uaaucaaaga agaaguacua gcuuauguag uccaacuucc acucuacgga      900

guaauagaca cccccugcug gaaacuacac acaucaccac uaugcacaac aaacacaaaa      960

gaaggcucaa acauaugccu aacaagaacu gacagaggau gguauuguga caaugcaggc     1020

ucugucucau ucuuuccaca agccgaaaca ugcaaaguuc aaucaaaccg aguuuucugu     1080

gacacaauga acucuagaac ucucccauca gaagucaacu uaugcaacgu ugacauauuc     1140

aacccaaaau augacuguaa aauaaugacu uccaaaacug auguaucauc cuccgucaua     1200

acaucccuag gagcuauugu aucauguuac gggaaaacca aaugcacagc cucaaacaaa     1260

aaccgcggua ucauaaaaac auuuucaaac ggaugugauu acguaagcaa uaaaggagua     1320

gacaccguau caguaggaaa uacacuauac uauguaaaua aacaagaagg aaaaucacua     1380

uaugucaaag gagaaccaau cauaaauuuc uaugacccac uuguauuccc auccgaugaa     1440

uuugacgcaa gcauuucaca ggucaacgaa aaaauaaacc aaucacuagc cuucaucaga     1500

aaaucagacg aacuacuaca uaacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

acaacaauca uaauaguuau cauaguaaua cuacuaucuc uaauagcugu cggacucuua     1620

cuauauugca aagcccgaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4243
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4243
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccugaaagcc      120

aacgccauaa ccacaauccu uaccgcaguc accuucugcu ucgccuccgg ucaaaacauc      180

acagaagagu ucuaccaauc caccuguucc gcagucagca aaggcuaccu cuccgcacuc      240

cgaaccggau gguacaccag cgucaucacc aucgaacuau ccaacauaaa ggaaaauaag      300

ugcaauggua cagaugccaa ggucaaacuc auaaagcaag aacucgacaa auacaaaaac      360

gccgucaccg aacuacaacu acuaaugcaa ucuacccccg caacaggcuc agguuccgcc      420

auagccuccg gcgucgccgu uugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aaauccgccc uacucucaac caacaaagca gucgucuccc ucucaaacgg agucucgguc      540

cucaccuuca aaguccucga ccucaaaaac uauauagaca aacaacuccu acccauacuc      600

aacaaacagu ccugcagcau auccaacauc gaaaccguga ucgaguucca acagaaaaac      660

aacagacucc ucgaaaucac ucgagaguuc uccguaaacg ccggcgucac aaccccaguc      720

ucaacauaca ugcucaccaa cagcgaacuc cuaucacuaa ucaacgacau gccuaucaca      780

aaugaucaga agaaacuaau gagcaacaac guccaaaucg uccgccaaca aucauacucc      840

aucaugugca ucauaaaaga agaaguccua gccuacgugg uccagcuacc ccucuacggc      900

guaauugaca ccccuugcug gaaacuacac acuucacccc ucugcacaac caacaccaaa      960

gaagguucaa acaucugccu cacacgaaca gaccgcggcu gguacugcga caacgccgga     1020

uccguauccu ucuuccccca agcagaaacc ugcaaaguuc aauccaaccg gguauucugc     1080

gacaccauga acucaagaac ccuucccucc gaaguaaauc uaugcaacgu cgacauauuc     1140

aacccaaaau acgacugcaa aaucaugacc uccaaaaccg augucuccag cagcgucauc     1200

accagccucg gcgccaucgu cuccugcuac ggcaaaacaa aauguacagc auccaacaaa     1260

aaccgaggca uaaucaaaac cuucuccaac gggugcgauu acgucagcaa caaaggcguc     1320

gacaccgucu ccgugggcaa cacccuauac uacgucaaca aacaagaagg caaaucacug     1380

uacguaaagg gcgaacccau caucaacuuc uaugacccuc ugguguuccc auccgaugaa     1440

uuugacgcau ccauaucuca ggucaacgaa aagaucaacc aaucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca caacgucaac gcugguaaaa gcaccaccaa caucaugauc     1560

accacaauca ucaucgucau aaucguuauc cuacucuccc uuauagcagu cggacuccuc     1620

cucuacugca aagcccgcua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4244
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4244
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4245
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4245
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4246
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4246
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4247
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4247
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4248
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4248
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4249
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4249
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4250
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4250
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucaucc ucaaagcaaa cgcaauaaca acaauacuaa cagcagucac uuucugcuuc      240

gcauccggac aaaauaucac agaagaauuu uaccaaucca ccugcucugc ugucuccaaa      300

ggauaccuau cugcccucag aaccgguugg uauacaucug ucauaaccau agaacuauca      360

aacauuaaag aaaacaaaug uaacggaaca gacgcaaaag ucaaacuuau aaaacaagaa      420

uuagacaaau acaaaaacgc agucacagaa uuacaacuac uaaugcaauc aaccccagca      480

accggaucag gauccgcaau agcuucagga guagcaguau guaaaguucu acacuuagaa      540

ggagaaguca acaaaauuaa auccgcacua uuaucaacca acaaagcagu cguaucuuua      600

ucaaacggag uaucuguacu uacauucaaa guacuagacc uaaaaaauua cauugauaaa      660

caauuacuac caauacuaaa caaacaauca uguuccaucu cuaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaaucaccc gagaauuuuc aguaaacgca      780

ggaguaacca cacccguauc uacauacaug cuaacaaacu cugaacuucu gagccuaaua      840

aaugacaugc caauaaccaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

cgacaacaau cuuacucaau caugugcaua aucaaagaag aaguacuagc uuauguaguc      960

caacuuccac ucuacggagu aauagacacc cccugcugga aacuacacac aucaccacua     1020

ugcacaacaa acacaaaaga aggcucaaac auaugccuaa caagaacuga cagaggaugg     1080

uauugugaca augcaggcuc ugucucauuc uuuccacaag ccgaaacaug caaaguucaa     1140

ucaaaccgag uuuucuguga cacaaugaac ucuagaacuc ucccaucaga agucaacuua     1200

ugcaacguug acauauucaa cccaaaauau gacuguaaaa uaaugacuuc caaaacugau     1260

guaucauccu ccgucauaac aucccuagga gcuauuguau cauguuacgg gaaaaccaaa     1320

ugcacagccu caaacaaaaa ccgcgguauc auaaaaacau uuucaaacgg augugauuac     1380

guaagcaaua aaggaguaga caccguauca guaggaaaua cacuauacua uguaaauaaa     1440

caagaaggaa aaucacuaua ugucaaagga gaaccaauca uaaauuucua ugacccacuu     1500

guauucccau ccgaugaauu ugacgcaagc auuucacagg ucaacgaaaa aauaaaccaa     1560

ucacuagccu ucaucagaaa aucagacgaa cuacuacaua acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac aacaaucaua auaguuauca uaguaauacu acuaucucua     1680

auagcugucg gacucuuacu auauugcaaa gcccgauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4251
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4251
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc ugaaagccaa cgccauaacc acaauccuua ccgcagucac cuucugcuuc      240

gccuccgguc aaaacaucac agaagaguuc uaccaaucca ccuguuccgc agucagcaaa      300

ggcuaccucu ccgcacuccg aaccggaugg uacaccagcg ucaucaccau cgaacuaucc      360

aacauaaagg aaaauaagug caaugguaca gaugccaagg ucaaacucau aaagcaagaa      420

cucgacaaau acaaaaacgc cgucaccgaa cuacaacuac uaaugcaauc uacccccgca      480

acaggcucag guuccgccau agccuccggc gucgccguuu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa auccgcccua cucucaacca acaaagcagu cgucucccuc      600

ucaaacggag ucucgguccu caccuucaaa guccucgacc ucaaaaacua uauagacaaa      660

caacuccuac ccauacucaa caaacagucc ugcagcauau ccaacaucga aaccgugauc      720

gaguuccaac agaaaaacaa cagacuccuc gaaaucacuc gagaguucuc cguaaacgcc      780

ggcgucacaa ccccagucuc aacauacaug cucaccaaca gcgaacuccu aucacuaauc      840

aacgacaugc cuaucacaaa ugaucagaag aaacuaauga gcaacaacgu ccaaaucguc      900

cgccaacaau cauacuccau caugugcauc auaaaagaag aaguccuagc cuacgugguc      960

cagcuacccc ucuacggcgu aauugacacc ccuugcugga aacuacacac uucaccccuc     1020

ugcacaacca acaccaaaga agguucaaac aucugccuca cacgaacaga ccgcggcugg     1080

uacugcgaca acgccggauc cguauccuuc uucccccaag cagaaaccug caaaguucaa     1140

uccaaccggg uauucugcga caccaugaac ucaagaaccc uucccuccga aguaaaucua     1200

ugcaacgucg acauauucaa cccaaaauac gacugcaaaa ucaugaccuc caaaaccgau     1260

gucuccagca gcgucaucac cagccucggc gccaucgucu ccugcuacgg caaaacaaaa     1320

uguacagcau ccaacaaaaa ccgaggcaua aucaaaaccu ucuccaacgg gugcgauuac     1380

gucagcaaca aaggcgucga caccgucucc gugggcaaca cccuauacua cgucaacaaa     1440

caagaaggca aaucacugua cguaaagggc gaacccauca ucaacuucua ugacccucug     1500

guguucccau ccgaugaauu ugacgcaucc auaucucagg ucaacgaaaa gaucaaccaa     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaca acgucaacgc ugguaaaagc     1620

accaccaaca ucaugaucac cacaaucauc aucgucauaa ucguuauccu acucucccuu     1680

auagcagucg gacuccuccu cuacugcaaa gcccgcuaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4252
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4252
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4253
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4253
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4254
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4254
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4255
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4255
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4256
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4256
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4257
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4257
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4258
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4258
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauccu caaagcaaac gcaauaacaa caauacuaac agcagucacu      180

uucugcuucg cauccggaca aaauaucaca gaagaauuuu accaauccac cugcucugcu      240

gucuccaaag gauaccuauc ugcccucaga accgguuggu auacaucugu cauaaccaua      300

gaacuaucaa acauuaaaga aaacaaaugu aacggaacag acgcaaaagu caaacuuaua      360

aaacaagaau uagacaaaua caaaaacgca gucacagaau uacaacuacu aaugcaauca      420

accccagcaa ccggaucagg auccgcaaua gcuucaggag uagcaguaug uaaaguucua      480

cacuuagaag gagaagucaa caaaauuaaa uccgcacuau uaucaaccaa caaagcaguc      540

guaucuuuau caaacggagu aucuguacuu acauucaaag uacuagaccu aaaaaauuac      600

auugauaaac aauuacuacc aauacuaaac aaacaaucau guuccaucuc uaacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agauuacuug aaaucacccg agaauuuuca      720

guaaacgcag gaguaaccac acccguaucu acauacaugc uaacaaacuc ugaacuucug      780

agccuaauaa augacaugcc aauaaccaac gaccaaaaaa aacuaauguc caacaacgua      840

caaauaguac gacaacaauc uuacucaauc augugcauaa ucaaagaaga aguacuagcu      900

uauguagucc aacuuccacu cuacggagua auagacaccc ccugcuggaa acuacacaca      960

ucaccacuau gcacaacaaa cacaaaagaa ggcucaaaca uaugccuaac aagaacugac     1020

agaggauggu auugugacaa ugcaggcucu gucucauucu uuccacaagc cgaaacaugc     1080

aaaguucaau caaaccgagu uuucugugac acaaugaacu cuagaacucu cccaucagaa     1140

gucaacuuau gcaacguuga cauauucaac ccaaaauaug acuguaaaau aaugacuucc     1200

aaaacugaug uaucauccuc cgucauaaca ucccuaggag cuauuguauc auguuacggg     1260

aaaaccaaau gcacagccuc aaacaaaaac cgcgguauca uaaaaacauu uucaaacgga     1320

ugugauuacg uaagcaauaa aggaguagac accguaucag uaggaaauac acuauacuau     1380

guaaauaaac aagaaggaaa aucacuauau gucaaaggag aaccaaucau aaauuucuau     1440

gacccacuug uauucccauc cgaugaauuu gacgcaagca uuucacaggu caacgaaaaa     1500

auaaaccaau cacuagccuu caucagaaaa ucagacgaac uacuacauaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaaca acaaucauaa uaguuaucau aguaauacua     1620

cuaucucuaa uagcugucgg acucuuacua uauugcaaag cccgauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4259
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4259
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu gaaagccaac gccauaacca caauccuuac cgcagucacc      180

uucugcuucg ccuccgguca aaacaucaca gaagaguucu accaauccac cuguuccgca      240

gucagcaaag gcuaccucuc cgcacuccga accggauggu acaccagcgu caucaccauc      300

gaacuaucca acauaaagga aaauaagugc aaugguacag augccaaggu caaacucaua      360

aagcaagaac ucgacaaaua caaaaacgcc gucaccgaac uacaacuacu aaugcaaucu      420

acccccgcaa caggcucagg uuccgccaua gccuccggcg ucgccguuug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaaa uccgcccuac ucucaaccaa caaagcaguc      540

gucucccucu caaacggagu cucgguccuc accuucaaag uccucgaccu caaaaacuau      600

auagacaaac aacuccuacc cauacucaac aaacaguccu gcagcauauc caacaucgaa      660

accgugaucg aguuccaaca gaaaaacaac agacuccucg aaaucacucg agaguucucc      720

guaaacgccg gcgucacaac cccagucuca acauacaugc ucaccaacag cgaacuccua      780

ucacuaauca acgacaugcc uaucacaaau gaucagaaga aacuaaugag caacaacguc      840

caaaucgucc gccaacaauc auacuccauc augugcauca uaaaagaaga aguccuagcc      900

uacguggucc agcuaccccu cuacggcgua auugacaccc cuugcuggaa acuacacacu      960

ucaccccucu gcacaaccaa caccaaagaa gguucaaaca ucugccucac acgaacagac     1020

cgcggcuggu acugcgacaa cgccggaucc guauccuucu ucccccaagc agaaaccugc     1080

aaaguucaau ccaaccgggu auucugcgac accaugaacu caagaacccu ucccuccgaa     1140

guaaaucuau gcaacgucga cauauucaac ccaaaauacg acugcaaaau caugaccucc     1200

aaaaccgaug ucuccagcag cgucaucacc agccucggcg ccaucgucuc cugcuacggc     1260

aaaacaaaau guacagcauc caacaaaaac cgaggcauaa ucaaaaccuu cuccaacggg     1320

ugcgauuacg ucagcaacaa aggcgucgac accgucuccg ugggcaacac ccuauacuac     1380

gucaacaaac aagaaggcaa aucacuguac guaaagggcg aacccaucau caacuucuau     1440

gacccucugg uguucccauc cgaugaauuu gacgcaucca uaucucaggu caacgaaaag     1500

aucaaccaau cccucgccuu cauacgcaaa uccgacgaac uccuacacaa cgucaacgcu     1560

gguaaaagca ccaccaacau caugaucacc acaaucauca ucgucauaau cguuauccua     1620

cucucccuua uagcagucgg acuccuccuc uacugcaaag cccgcuaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4260
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4260
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4261
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4261
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4262
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4262
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4263
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4263
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4264
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4264
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4265
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4265
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4266
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4266
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauccucaaa gcaaacgcaa uaacaacaau acuaacagca      120

gucacuuucu gcuucgcauc cggacaaaau aucacagaag aauuuuacca auccaccugc      180

ucugcugucu ccaaaggaua ccuaucugcc cucagaaccg guugguauac aucugucaua      240

accauagaac uaucaaacau uaaagaaaac aaauguaacg gaacagacgc aaaagucaaa      300

cuuauaaaac aagaauuaga caaauacaaa aacgcaguca cagaauuaca acuacuaaug      360

caaucaaccc cagcaaccgg aucaggaucc gcaauagcuu caggaguagc aguauguaaa      420

guucuacacu uagaaggaga agucaacaaa auuaaauccg cacuauuauc aaccaacaaa      480

gcagucguau cuuuaucaaa cggaguaucu guacuuacau ucaaaguacu agaccuaaaa      540

aauuacauug auaaacaauu acuaccaaua cuaaacaaac aaucauguuc caucucuaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagau uacuugaaau cacccgagaa      660

uuuucaguaa acgcaggagu aaccacaccc guaucuacau acaugcuaac aaacucugaa      720

cuucugagcc uaauaaauga caugccaaua accaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa uaguacgaca acaaucuuac ucaaucaugu gcauaaucaa agaagaagua      840

cuagcuuaug uaguccaacu uccacucuac ggaguaauag acacccccug cuggaaacua      900

cacacaucac cacuaugcac aacaaacaca aaagaaggcu caaacauaug ccuaacaaga      960

acugacagag gaugguauug ugacaaugca ggcucugucu cauucuuucc acaagccgaa     1020

acaugcaaag uucaaucaaa ccgaguuuuc ugugacacaa ugaacucuag aacucuccca     1080

ucagaaguca acuuaugcaa cguugacaua uucaacccaa aauaugacug uaaaauaaug     1140

acuuccaaaa cugauguauc auccuccguc auaacauccc uaggagcuau uguaucaugu     1200

uacgggaaaa ccaaaugcac agccucaaac aaaaaccgcg guaucauaaa aacauuuuca     1260

aacggaugug auuacguaag caauaaagga guagacaccg uaucaguagg aaauacacua     1320

uacuauguaa auaaacaaga aggaaaauca cuauauguca aaggagaacc aaucauaaau     1380

uucuaugacc cacuuguauu cccauccgau gaauuugacg caagcauuuc acaggucaac     1440

gaaaaaauaa accaaucacu agccuucauc agaaaaucag acgaacuacu acauaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaacaacaa ucauaauagu uaucauagua     1560

auacuacuau cucuaauagc ugucggacuc uuacuauauu gcaaagcccg auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4267
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4267
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccugaaa gccaacgcca uaaccacaau ccuuaccgca      120

gucaccuucu gcuucgccuc cggucaaaac aucacagaag aguucuacca auccaccugu      180

uccgcaguca gcaaaggcua ccucuccgca cuccgaaccg gaugguacac cagcgucauc      240

accaucgaac uauccaacau aaaggaaaau aagugcaaug guacagaugc caaggucaaa      300

cucauaaagc aagaacucga caaauacaaa aacgccguca ccgaacuaca acuacuaaug      360

caaucuaccc ccgcaacagg cucagguucc gccauagccu ccggcgucgc cguuugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gcagucgucu cccucucaaa cggagucucg guccucaccu ucaaaguccu cgaccucaaa      540

aacuauauag acaaacaacu ccuacccaua cucaacaaac aguccugcag cauauccaac      600

aucgaaaccg ugaucgaguu ccaacagaaa aacaacagac uccucgaaau cacucgagag      660

uucuccguaa acgccggcgu cacaacccca gucucaacau acaugcucac caacagcgaa      720

cuccuaucac uaaucaacga caugccuauc acaaaugauc agaagaaacu aaugagcaac      780

aacguccaaa ucguccgcca acaaucauac uccaucaugu gcaucauaaa agaagaaguc      840

cuagccuacg ugguccagcu accccucuac ggcguaauug acaccccuug cuggaaacua      900

cacacuucac cccucugcac aaccaacacc aaagaagguu caaacaucug ccucacacga      960

acagaccgcg gcugguacug cgacaacgcc ggauccguau ccuucuuccc ccaagcagaa     1020

accugcaaag uucaauccaa ccggguauuc ugcgacacca ugaacucaag aacccuuccc     1080

uccgaaguaa aucuaugcaa cgucgacaua uucaacccaa aauacgacug caaaaucaug     1140

accuccaaaa ccgaugucuc cagcagcguc aucaccagcc ucggcgccau cgucuccugc     1200

uacggcaaaa caaaauguac agcauccaac aaaaaccgag gcauaaucaa aaccuucucc     1260

aacgggugcg auuacgucag caacaaaggc gucgacaccg ucuccguggg caacacccua     1320

uacuacguca acaaacaaga aggcaaauca cuguacguaa agggcgaacc caucaucaac     1380

uucuaugacc cucugguguu cccauccgau gaauuugacg cauccauauc ucaggucaac     1440

gaaaagauca accaaucccu cgccuucaua cgcaaauccg acgaacuccu acacaacguc     1500

aacgcuggua aaagcaccac caacaucaug aucaccacaa ucaucaucgu cauaaucguu     1560

auccuacucu cccuuauagc agucggacuc cuccucuacu gcaaagcccg cuaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4268
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4268
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4269
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4269
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      600

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      660

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1140

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1260

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1380

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1440

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1500

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4270
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4270
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1500

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4271
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4271
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      600

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      660

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      720

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      840

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      900

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      960

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua     1020

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca     1080

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc     1140

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1200

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1260

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1320

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1380

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1440

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1500

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1560

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1620

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1680

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1740

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4272
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4272
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4273
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4273
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      600

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      660

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      720

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      840

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      900

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      960

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug     1020

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu     1080

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga     1140

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1200

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1260

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1320

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1380

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1440

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1500

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1560

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1620

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1740

cugaucgccg ugggccuccu gcuguacugc aaagcuagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4274
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4274
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaauuacuca uccucaaagc aaacgcaaua acaacaauac uaacagcagu cacuuucugc      300

uucgcauccg gacaaaauau cacagaagaa uuuuaccaau ccaccugcuc ugcugucucc      360

aaaggauacc uaucugcccu cagaaccggu ugguauacau cugucauaac cauagaacua      420

ucaaacauua aagaaaacaa auguaacgga acagacgcaa aagucaaacu uauaaaacaa      480

gaauuagaca aauacaaaaa cgcagucaca gaauuacaac uacuaaugca aucaacccca      540

gcaaccggau caggauccgc aauagcuuca ggaguagcag uauguaaagu ucuacacuua      600

gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa ccaacaaagc agucguaucu      660

uuaucaaacg gaguaucugu acuuacauuc aaaguacuag accuaaaaaa uuacauugau      720

aaacaauuac uaccaauacu aaacaaacaa ucauguucca ucucuaacau agaaacagua      780

auagaauuuc aacaaaaaaa uaacagauua cuugaaauca cccgagaauu uucaguaaac      840

gcaggaguaa ccacacccgu aucuacauac augcuaacaa acucugaacu ucugagccua      900

auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa uguccaacaa cguacaaaua      960

guacgacaac aaucuuacuc aaucaugugc auaaucaaag aagaaguacu agcuuaugua     1020

guccaacuuc cacucuacgg aguaauagac acccccugcu ggaaacuaca cacaucacca     1080

cuaugcacaa caaacacaaa agaaggcuca aacauaugcc uaacaagaac ugacagagga     1140

ugguauugug acaaugcagg cucugucuca uucuuuccac aagccgaaac augcaaaguu     1200

caaucaaacc gaguuuucug ugacacaaug aacucuagaa cucucccauc agaagucaac     1260

uuaugcaacg uugacauauu caacccaaaa uaugacugua aaauaaugac uuccaaaacu     1320

gauguaucau ccuccgucau aacaucccua ggagcuauug uaucauguua cgggaaaacc     1380

aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa cauuuucaaa cggaugugau     1440

uacguaagca auaaaggagu agacaccgua ucaguaggaa auacacuaua cuauguaaau     1500

aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa ucauaaauuu cuaugaccca     1560

cuuguauucc cauccgauga auuugacgca agcauuucac aggucaacga aaaaauaaac     1620

caaucacuag ccuucaucag aaaaucagac gaacuacuac auaacguaaa cgccggaaaa     1680

ucaacaacca acauaaugau aacaacaauc auaauaguua ucauaguaau acuacuaucu     1740

cuaauagcug ucggacucuu acuauauugc aaagcccgau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4275
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4275
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuaa uccugaaagc caacgccaua accacaaucc uuaccgcagu caccuucugc      300

uucgccuccg gucaaaacau cacagaagag uucuaccaau ccaccuguuc cgcagucagc      360

aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca gcgucaucac caucgaacua      420

uccaacauaa aggaaaauaa gugcaauggu acagaugcca aggucaaacu cauaaagcaa      480

gaacucgaca aauacaaaaa cgccgucacc gaacuacaac uacuaaugca aucuaccccc      540

gcaacaggcu cagguuccgc cauagccucc ggcgucgccg uuugcaaagu ccuccaccuc      600

gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa ccaacaaagc agucgucucc      660

cucucaaacg gagucucggu ccucaccuuc aaaguccucg accucaaaaa cuauauagac      720

aaacaacucc uacccauacu caacaaacag uccugcagca uauccaacau cgaaaccgug      780

aucgaguucc aacagaaaaa caacagacuc cucgaaauca cucgagaguu cuccguaaac      840

gccggcguca caaccccagu cucaacauac augcucacca acagcgaacu ccuaucacua      900

aucaacgaca ugccuaucac aaaugaucag aagaaacuaa ugagcaacaa cguccaaauc      960

guccgccaac aaucauacuc caucaugugc aucauaaaag aagaaguccu agccuacgug     1020

guccagcuac cccucuacgg cguaauugac accccuugcu ggaaacuaca cacuucaccc     1080

cucugcacaa ccaacaccaa agaagguuca aacaucugcc ucacacgaac agaccgcggc     1140

ugguacugcg acaacgccgg auccguaucc uucuuccccc aagcagaaac cugcaaaguu     1200

caauccaacc ggguauucug cgacaccaug aacucaagaa cccuucccuc cgaaguaaau     1260

cuaugcaacg ucgacauauu caacccaaaa uacgacugca aaaucaugac cuccaaaacc     1320

gaugucucca gcagcgucau caccagccuc ggcgccaucg ucuccugcua cggcaaaaca     1380

aaauguacag cauccaacaa aaaccgaggc auaaucaaaa ccuucuccaa cgggugcgau     1440

uacgucagca acaaaggcgu cgacaccguc uccgugggca acacccuaua cuacgucaac     1500

aaacaagaag gcaaaucacu guacguaaag ggcgaaccca ucaucaacuu cuaugacccu     1560

cugguguucc cauccgauga auuugacgca uccauaucuc aggucaacga aaagaucaac     1620

caaucccucg ccuucauacg caaauccgac gaacuccuac acaacgucaa cgcugguaaa     1680

agcaccacca acaucaugau caccacaauc aucaucguca uaaucguuau ccuacucucc     1740

cuuauagcag ucggacuccu ccucuacugc aaagcccgcu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4276
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4276
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4277
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4277
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4278
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4278
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4279
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4279
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca      900

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc      960

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1020

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1200

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1320

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4280
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4280
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4281
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4281
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu      900

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga      960

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1020

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1320

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguacugc aaagcuagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4282
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4282
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaauuacuca uccucaaagc aaacgcaaua acaacaauac uaacagcagu cacuuucugc      120

uucgcauccg gacaaaauau cacagaagaa uuuuaccaau ccaccugcuc ugcugucucc      180

aaaggauacc uaucugcccu cagaaccggu ugguauacau cugucauaac cauagaacua      240

ucaaacauua aagaaaacaa auguaacgga acagacgcaa aagucaaacu uauaaaacaa      300

gaauuagaca aauacaaaaa cgcagucaca gaauuacaac uacuaaugca aucaacccca      360

gcaaccggau caggauccgc aauagcuuca ggaguagcag uauguaaagu ucuacacuua      420

gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa ccaacaaagc agucguaucu      480

uuaucaaacg gaguaucugu acuuacauuc aaaguacuag accuaaaaaa uuacauugau      540

aaacaauuac uaccaauacu aaacaaacaa ucauguucca ucucuaacau agaaacagua      600

auagaauuuc aacaaaaaaa uaacagauua cuugaaauca cccgagaauu uucaguaaac      660

gcaggaguaa ccacacccgu aucuacauac augcuaacaa acucugaacu ucugagccua      720

auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa uguccaacaa cguacaaaua      780

guacgacaac aaucuuacuc aaucaugugc auaaucaaag aagaaguacu agcuuaugua      840

guccaacuuc cacucuacgg aguaauagac acccccugcu ggaaacuaca cacaucacca      900

cuaugcacaa caaacacaaa agaaggcuca aacauaugcc uaacaagaac ugacagagga      960

ugguauugug acaaugcagg cucugucuca uucuuuccac aagccgaaac augcaaaguu     1020

caaucaaacc gaguuuucug ugacacaaug aacucuagaa cucucccauc agaagucaac     1080

uuaugcaacg uugacauauu caacccaaaa uaugacugua aaauaaugac uuccaaaacu     1140

gauguaucau ccuccgucau aacaucccua ggagcuauug uaucauguua cgggaaaacc     1200

aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa cauuuucaaa cggaugugau     1260

uacguaagca auaaaggagu agacaccgua ucaguaggaa auacacuaua cuauguaaau     1320

aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa ucauaaauuu cuaugaccca     1380

cuuguauucc cauccgauga auuugacgca agcauuucac aggucaacga aaaaauaaac     1440

caaucacuag ccuucaucag aaaaucagac gaacuacuac auaacguaaa cgccggaaaa     1500

ucaacaacca acauaaugau aacaacaauc auaauaguua ucauaguaau acuacuaucu     1560

cuaauagcug ucggacucuu acuauauugc aaagcccgau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4283
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4283
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuaa uccugaaagc caacgccaua accacaaucc uuaccgcagu caccuucugc      120

uucgccuccg gucaaaacau cacagaagag uucuaccaau ccaccuguuc cgcagucagc      180

aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca gcgucaucac caucgaacua      240

uccaacauaa aggaaaauaa gugcaauggu acagaugcca aggucaaacu cauaaagcaa      300

gaacucgaca aauacaaaaa cgccgucacc gaacuacaac uacuaaugca aucuaccccc      360

gcaacaggcu cagguuccgc cauagccucc ggcgucgccg uuugcaaagu ccuccaccuc      420

gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa ccaacaaagc agucgucucc      480

cucucaaacg gagucucggu ccucaccuuc aaaguccucg accucaaaaa cuauauagac      540

aaacaacucc uacccauacu caacaaacag uccugcagca uauccaacau cgaaaccgug      600

aucgaguucc aacagaaaaa caacagacuc cucgaaauca cucgagaguu cuccguaaac      660

gccggcguca caaccccagu cucaacauac augcucacca acagcgaacu ccuaucacua      720

aucaacgaca ugccuaucac aaaugaucag aagaaacuaa ugagcaacaa cguccaaauc      780

guccgccaac aaucauacuc caucaugugc aucauaaaag aagaaguccu agccuacgug      840

guccagcuac cccucuacgg cguaauugac accccuugcu ggaaacuaca cacuucaccc      900

cucugcacaa ccaacaccaa agaagguuca aacaucugcc ucacacgaac agaccgcggc      960

ugguacugcg acaacgccgg auccguaucc uucuuccccc aagcagaaac cugcaaaguu     1020

caauccaacc ggguauucug cgacaccaug aacucaagaa cccuucccuc cgaaguaaau     1080

cuaugcaacg ucgacauauu caacccaaaa uacgacugca aaaucaugac cuccaaaacc     1140

gaugucucca gcagcgucau caccagccuc ggcgccaucg ucuccugcua cggcaaaaca     1200

aaauguacag cauccaacaa aaaccgaggc auaaucaaaa ccuucuccaa cgggugcgau     1260

uacgucagca acaaaggcgu cgacaccguc uccgugggca acacccuaua cuacgucaac     1320

aaacaagaag gcaaaucacu guacguaaag ggcgaaccca ucaucaacuu cuaugacccu     1380

cugguguucc cauccgauga auuugacgca uccauaucuc aggucaacga aaagaucaac     1440

caaucccucg ccuucauacg caaauccgac gaacuccuac acaacgucaa cgcugguaaa     1500

agcaccacca acaucaugau caccacaauc aucaucguca uaaucguuau ccuacucucc     1560

cuuauagcag ucggacuccu ccucuacugc aaagcccgcu aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  4284
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4284
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4285
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4285
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4286
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4286
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4287
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4287
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4288
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4288
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4289
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4289
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4290
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4290
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uccucaaagc aaacgcaaua acaacaauac      120

uaacagcagu cacuuucugc uucgcauccg gacaaaauau cacagaagaa uuuuaccaau      180

ccaccugcuc ugcugucucc aaaggauacc uaucugcccu cagaaccggu ugguauacau      240

cugucauaac cauagaacua ucaaacauua aagaaaacaa auguaacgga acagacgcaa      300

aagucaaacu uauaaaacaa gaauuagaca aauacaaaaa cgcagucaca gaauuacaac      360

uacuaaugca aucaacccca gcaaccggau caggauccgc aauagcuuca ggaguagcag      420

uauguaaagu ucuacacuua gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa      480

ccaacaaagc agucguaucu uuaucaaacg gaguaucugu acuuacauuc aaaguacuag      540

accuaaaaaa uuacauugau aaacaauuac uaccaauacu aaacaaacaa ucauguucca      600

ucucuaacau agaaacagua auagaauuuc aacaaaaaaa uaacagauua cuugaaauca      660

cccgagaauu uucaguaaac gcaggaguaa ccacacccgu aucuacauac augcuaacaa      720

acucugaacu ucugagccua auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaaua guacgacaac aaucuuacuc aaucaugugc auaaucaaag      840

aagaaguacu agcuuaugua guccaacuuc cacucuacgg aguaauagac acccccugcu      900

ggaaacuaca cacaucacca cuaugcacaa caaacacaaa agaaggcuca aacauaugcc      960

uaacaagaac ugacagagga ugguauugug acaaugcagg cucugucuca uucuuuccac     1020

aagccgaaac augcaaaguu caaucaaacc gaguuuucug ugacacaaug aacucuagaa     1080

cucucccauc agaagucaac uuaugcaacg uugacauauu caacccaaaa uaugacugua     1140

aaauaaugac uuccaaaacu gauguaucau ccuccgucau aacaucccua ggagcuauug     1200

uaucauguua cgggaaaacc aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa     1260

cauuuucaaa cggaugugau uacguaagca auaaaggagu agacaccgua ucaguaggaa     1320

auacacuaua cuauguaaau aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa     1380

ucauaaauuu cuaugaccca cuuguauucc cauccgauga auuugacgca agcauuucac     1440

aggucaacga aaaaauaaac caaucacuag ccuucaucag aaaaucagac gaacuacuac     1500

auaacguaaa cgccggaaaa ucaacaacca acauaaugau aacaacaauc auaauaguua     1560

ucauaguaau acuacuaucu cuaauagcug ucggacucuu acuauauugc aaagcccgau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4291
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4291
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccugaaagc caacgccaua accacaaucc      120

uuaccgcagu caccuucugc uucgccuccg gucaaaacau cacagaagag uucuaccaau      180

ccaccuguuc cgcagucagc aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca      240

gcgucaucac caucgaacua uccaacauaa aggaaaauaa gugcaauggu acagaugcca      300

aggucaaacu cauaaagcaa gaacucgaca aauacaaaaa cgccgucacc gaacuacaac      360

uacuaaugca aucuaccccc gcaacaggcu cagguuccgc cauagccucc ggcgucgccg      420

uuugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc agucgucucc cucucaaacg gagucucggu ccucaccuuc aaaguccucg      540

accucaaaaa cuauauagac aaacaacucc uacccauacu caacaaacag uccugcagca      600

uauccaacau cgaaaccgug aucgaguucc aacagaaaaa caacagacuc cucgaaauca      660

cucgagaguu cuccguaaac gccggcguca caaccccagu cucaacauac augcucacca      720

acagcgaacu ccuaucacua aucaacgaca ugccuaucac aaaugaucag aagaaacuaa      780

ugagcaacaa cguccaaauc guccgccaac aaucauacuc caucaugugc aucauaaaag      840

aagaaguccu agccuacgug guccagcuac cccucuacgg cguaauugac accccuugcu      900

ggaaacuaca cacuucaccc cucugcacaa ccaacaccaa agaagguuca aacaucugcc      960

ucacacgaac agaccgcggc ugguacugcg acaacgccgg auccguaucc uucuuccccc     1020

aagcagaaac cugcaaaguu caauccaacc ggguauucug cgacaccaug aacucaagaa     1080

cccuucccuc cgaaguaaau cuaugcaacg ucgacauauu caacccaaaa uacgacugca     1140

aaaucaugac cuccaaaacc gaugucucca gcagcgucau caccagccuc ggcgccaucg     1200

ucuccugcua cggcaaaaca aaauguacag cauccaacaa aaaccgaggc auaaucaaaa     1260

ccuucuccaa cgggugcgau uacgucagca acaaaggcgu cgacaccguc uccgugggca     1320

acacccuaua cuacgucaac aaacaagaag gcaaaucacu guacguaaag ggcgaaccca     1380

ucaucaacuu cuaugacccu cugguguucc cauccgauga auuugacgca uccauaucuc     1440

aggucaacga aaagaucaac caaucccucg ccuucauacg caaauccgac gaacuccuac     1500

acaacgucaa cgcugguaaa agcaccacca acaucaugau caccacaauc aucaucguca     1560

uaaucguuau ccuacucucc cuuauagcag ucggacuccu ccucuacugc aaagcccgcu     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4292
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4292
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4293
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4293
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4294
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4294
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4295
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4295
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4296
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4296
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4297
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4297
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4298
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4298
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uccucaaagc aaacgcaaua acaacaauac      120

uaacagcagu cacuuucugc uucgcauccg gacaaaauau cacagaagaa uuuuaccaau      180

ccaccugcuc ugcugucucc aaaggauacc uaucugcccu cagaaccggu ugguauacau      240

cugucauaac cauagaacua ucaaacauua aagaaaacaa auguaacgga acagacgcaa      300

aagucaaacu uauaaaacaa gaauuagaca aauacaaaaa cgcagucaca gaauuacaac      360

uacuaaugca aucaacccca gcaaccggau caggauccgc aauagcuuca ggaguagcag      420

uauguaaagu ucuacacuua gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa      480

ccaacaaagc agucguaucu uuaucaaacg gaguaucugu acuuacauuc aaaguacuag      540

accuaaaaaa uuacauugau aaacaauuac uaccaauacu aaacaaacaa ucauguucca      600

ucucuaacau agaaacagua auagaauuuc aacaaaaaaa uaacagauua cuugaaauca      660

cccgagaauu uucaguaaac gcaggaguaa ccacacccgu aucuacauac augcuaacaa      720

acucugaacu ucugagccua auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaaua guacgacaac aaucuuacuc aaucaugugc auaaucaaag      840

aagaaguacu agcuuaugua guccaacuuc cacucuacgg aguaauagac acccccugcu      900

ggaaacuaca cacaucacca cuaugcacaa caaacacaaa agaaggcuca aacauaugcc      960

uaacaagaac ugacagagga ugguauugug acaaugcagg cucugucuca uucuuuccac     1020

aagccgaaac augcaaaguu caaucaaacc gaguuuucug ugacacaaug aacucuagaa     1080

cucucccauc agaagucaac uuaugcaacg uugacauauu caacccaaaa uaugacugua     1140

aaauaaugac uuccaaaacu gauguaucau ccuccgucau aacaucccua ggagcuauug     1200

uaucauguua cgggaaaacc aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa     1260

cauuuucaaa cggaugugau uacguaagca auaaaggagu agacaccgua ucaguaggaa     1320

auacacuaua cuauguaaau aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa     1380

ucauaaauuu cuaugaccca cuuguauucc cauccgauga auuugacgca agcauuucac     1440

aggucaacga aaaaauaaac caaucacuag ccuucaucag aaaaucagac gaacuacuac     1500

auaacguaaa cgccggaaaa ucaacaacca acauaaugau aacaacaauc auaauaguua     1560

ucauaguaau acuacuaucu cuaauagcug ucggacucuu acuauauugc aaagcccgau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4299
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4299
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccugaaagc caacgccaua accacaaucc      120

uuaccgcagu caccuucugc uucgccuccg gucaaaacau cacagaagag uucuaccaau      180

ccaccuguuc cgcagucagc aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca      240

gcgucaucac caucgaacua uccaacauaa aggaaaauaa gugcaauggu acagaugcca      300

aggucaaacu cauaaagcaa gaacucgaca aauacaaaaa cgccgucacc gaacuacaac      360

uacuaaugca aucuaccccc gcaacaggcu cagguuccgc cauagccucc ggcgucgccg      420

uuugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc agucgucucc cucucaaacg gagucucggu ccucaccuuc aaaguccucg      540

accucaaaaa cuauauagac aaacaacucc uacccauacu caacaaacag uccugcagca      600

uauccaacau cgaaaccgug aucgaguucc aacagaaaaa caacagacuc cucgaaauca      660

cucgagaguu cuccguaaac gccggcguca caaccccagu cucaacauac augcucacca      720

acagcgaacu ccuaucacua aucaacgaca ugccuaucac aaaugaucag aagaaacuaa      780

ugagcaacaa cguccaaauc guccgccaac aaucauacuc caucaugugc aucauaaaag      840

aagaaguccu agccuacgug guccagcuac cccucuacgg cguaauugac accccuugcu      900

ggaaacuaca cacuucaccc cucugcacaa ccaacaccaa agaagguuca aacaucugcc      960

ucacacgaac agaccgcggc ugguacugcg acaacgccgg auccguaucc uucuuccccc     1020

aagcagaaac cugcaaaguu caauccaacc ggguauucug cgacaccaug aacucaagaa     1080

cccuucccuc cgaaguaaau cuaugcaacg ucgacauauu caacccaaaa uacgacugca     1140

aaaucaugac cuccaaaacc gaugucucca gcagcgucau caccagccuc ggcgccaucg     1200

ucuccugcua cggcaaaaca aaauguacag cauccaacaa aaaccgaggc auaaucaaaa     1260

ccuucuccaa cgggugcgau uacgucagca acaaaggcgu cgacaccguc uccgugggca     1320

acacccuaua cuacgucaac aaacaagaag gcaaaucacu guacguaaag ggcgaaccca     1380

ucaucaacuu cuaugacccu cugguguucc cauccgauga auuugacgca uccauaucuc     1440

aggucaacga aaagaucaac caaucccucg ccuucauacg caaauccgac gaacuccuac     1500

acaacgucaa cgcugguaaa agcaccacca acaucaugau caccacaauc aucaucguca     1560

uaaucguuau ccuacucucc cuuauagcag ucggacuccu ccucuacugc aaagcccgcu     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  4300
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4300
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4301
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4301
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4302
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4302
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4303
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4303
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4304
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4304
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4305
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4305
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4306
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4306
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauccu caaagcaaac gcaauaacaa caauacuaac agcagucacu      180

uucugcuucg cauccggaca aaauaucaca gaagaauuuu accaauccac cugcucugcu      240

gucuccaaag gauaccuauc ugcccucaga accgguuggu auacaucugu cauaaccaua      300

gaacuaucaa acauuaaaga aaacaaaugu aacggaacag acgcaaaagu caaacuuaua      360

aaacaagaau uagacaaaua caaaaacgca gucacagaau uacaacuacu aaugcaauca      420

accccagcaa ccggaucagg auccgcaaua gcuucaggag uagcaguaug uaaaguucua      480

cacuuagaag gagaagucaa caaaauuaaa uccgcacuau uaucaaccaa caaagcaguc      540

guaucuuuau caaacggagu aucuguacuu acauucaaag uacuagaccu aaaaaauuac      600

auugauaaac aauuacuacc aauacuaaac aaacaaucau guuccaucuc uaacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agauuacuug aaaucacccg agaauuuuca      720

guaaacgcag gaguaaccac acccguaucu acauacaugc uaacaaacuc ugaacuucug      780

agccuaauaa augacaugcc aauaaccaac gaccaaaaaa aacuaauguc caacaacgua      840

caaauaguac gacaacaauc uuacucaauc augugcauaa ucaaagaaga aguacuagcu      900

uauguagucc aacuuccacu cuacggagua auagacaccc ccugcuggaa acuacacaca      960

ucaccacuau gcacaacaaa cacaaaagaa ggcucaaaca uaugccuaac aagaacugac     1020

agaggauggu auugugacaa ugcaggcucu gucucauucu uuccacaagc cgaaacaugc     1080

aaaguucaau caaaccgagu uuucugugac acaaugaacu cuagaacucu cccaucagaa     1140

gucaacuuau gcaacguuga cauauucaac ccaaaauaug acuguaaaau aaugacuucc     1200

aaaacugaug uaucauccuc cgucauaaca ucccuaggag cuauuguauc auguuacggg     1260

aaaaccaaau gcacagccuc aaacaaaaac cgcgguauca uaaaaacauu uucaaacgga     1320

ugugauuacg uaagcaauaa aggaguagac accguaucag uaggaaauac acuauacuau     1380

guaaauaaac aagaaggaaa aucacuauau gucaaaggag aaccaaucau aaauuucuau     1440

gacccacuug uauucccauc cgaugaauuu gacgcaagca uuucacaggu caacgaaaaa     1500

auaaaccaau cacuagccuu caucagaaaa ucagacgaac uacuacauaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaaca acaaucauaa uaguuaucau aguaauacua     1620

cuaucucuaa uagcugucgg acucuuacua uauugcaaag cccgauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4307
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4307
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu gaaagccaac gccauaacca caauccuuac cgcagucacc      180

uucugcuucg ccuccgguca aaacaucaca gaagaguucu accaauccac cuguuccgca      240

gucagcaaag gcuaccucuc cgcacuccga accggauggu acaccagcgu caucaccauc      300

gaacuaucca acauaaagga aaauaagugc aaugguacag augccaaggu caaacucaua      360

aagcaagaac ucgacaaaua caaaaacgcc gucaccgaac uacaacuacu aaugcaaucu      420

acccccgcaa caggcucagg uuccgccaua gccuccggcg ucgccguuug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaaa uccgcccuac ucucaaccaa caaagcaguc      540

gucucccucu caaacggagu cucgguccuc accuucaaag uccucgaccu caaaaacuau      600

auagacaaac aacuccuacc cauacucaac aaacaguccu gcagcauauc caacaucgaa      660

accgugaucg aguuccaaca gaaaaacaac agacuccucg aaaucacucg agaguucucc      720

guaaacgccg gcgucacaac cccagucuca acauacaugc ucaccaacag cgaacuccua      780

ucacuaauca acgacaugcc uaucacaaau gaucagaaga aacuaaugag caacaacguc      840

caaaucgucc gccaacaauc auacuccauc augugcauca uaaaagaaga aguccuagcc      900

uacguggucc agcuaccccu cuacggcgua auugacaccc cuugcuggaa acuacacacu      960

ucaccccucu gcacaaccaa caccaaagaa gguucaaaca ucugccucac acgaacagac     1020

cgcggcuggu acugcgacaa cgccggaucc guauccuucu ucccccaagc agaaaccugc     1080

aaaguucaau ccaaccgggu auucugcgac accaugaacu caagaacccu ucccuccgaa     1140

guaaaucuau gcaacgucga cauauucaac ccaaaauacg acugcaaaau caugaccucc     1200

aaaaccgaug ucuccagcag cgucaucacc agccucggcg ccaucgucuc cugcuacggc     1260

aaaacaaaau guacagcauc caacaaaaac cgaggcauaa ucaaaaccuu cuccaacggg     1320

ugcgauuacg ucagcaacaa aggcgucgac accgucuccg ugggcaacac ccuauacuac     1380

gucaacaaac aagaaggcaa aucacuguac guaaagggcg aacccaucau caacuucuau     1440

gacccucugg uguucccauc cgaugaauuu gacgcaucca uaucucaggu caacgaaaag     1500

aucaaccaau cccucgccuu cauacgcaaa uccgacgaac uccuacacaa cgucaacgcu     1560

gguaaaagca ccaccaacau caugaucacc acaaucauca ucgucauaau cguuauccua     1620

cucucccuua uagcagucgg acuccuccuc uacugcaaag cccgcuaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  4308
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4308
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4309
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4309
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4310
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4310
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4311
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4311
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4312
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4312
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4313
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4313
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4314
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4314
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau ccucaaagca      120

aacgcaauaa caacaauacu aacagcaguc acuuucugcu ucgcauccgg acaaaauauc      180

acagaagaau uuuaccaauc caccugcucu gcugucucca aaggauaccu aucugcccuc      240

agaaccgguu gguauacauc ugucauaacc auagaacuau caaacauuaa agaaaacaaa      300

uguaacggaa cagacgcaaa agucaaacuu auaaaacaag aauuagacaa auacaaaaac      360

gcagucacag aauuacaacu acuaaugcaa ucaaccccag caaccggauc aggauccgca      420

auagcuucag gaguagcagu auguaaaguu cuacacuuag aaggagaagu caacaaaauu      480

aaauccgcac uauuaucaac caacaaagca gucguaucuu uaucaaacgg aguaucugua      540

cuuacauuca aaguacuaga ccuaaaaaau uacauugaua aacaauuacu accaauacua      600

aacaaacaau cauguuccau cucuaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaaucac ccgagaauuu ucaguaaacg caggaguaac cacacccgua      720

ucuacauaca ugcuaacaaa cucugaacuu cugagccuaa uaaaugacau gccaauaacc      780

aacgaccaaa aaaaacuaau guccaacaac guacaaauag uacgacaaca aucuuacuca      840

aucaugugca uaaucaaaga agaaguacua gcuuauguag uccaacuucc acucuacgga      900

guaauagaca cccccugcug gaaacuacac acaucaccac uaugcacaac aaacacaaaa      960

gaaggcucaa acauaugccu aacaagaacu gacagaggau gguauuguga caaugcaggc     1020

ucugucucau ucuuuccaca agccgaaaca ugcaaaguuc aaucaaaccg aguuuucugu     1080

gacacaauga acucuagaac ucucccauca gaagucaacu uaugcaacgu ugacauauuc     1140

aacccaaaau augacuguaa aauaaugacu uccaaaacug auguaucauc cuccgucaua     1200

acaucccuag gagcuauugu aucauguuac gggaaaacca aaugcacagc cucaaacaaa     1260

aaccgcggua ucauaaaaac auuuucaaac ggaugugauu acguaagcaa uaaaggagua     1320

gacaccguau caguaggaaa uacacuauac uauguaaaua aacaagaagg aaaaucacua     1380

uaugucaaag gagaaccaau cauaaauuuc uaugacccac uuguauuccc auccgaugaa     1440

uuugacgcaa gcauuucaca ggucaacgaa aaaauaaacc aaucacuagc cuucaucaga     1500

aaaucagacg aacuacuaca uaacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

acaacaauca uaauaguuau cauaguaaua cuacuaucuc uaauagcugu cggacucuua     1620

cuauauugca aagcccgaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4315
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4315
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccugaaagcc      120

aacgccauaa ccacaauccu uaccgcaguc accuucugcu ucgccuccgg ucaaaacauc      180

acagaagagu ucuaccaauc caccuguucc gcagucagca aaggcuaccu cuccgcacuc      240

cgaaccggau gguacaccag cgucaucacc aucgaacuau ccaacauaaa ggaaaauaag      300

ugcaauggua cagaugccaa ggucaaacuc auaaagcaag aacucgacaa auacaaaaac      360

gccgucaccg aacuacaacu acuaaugcaa ucuacccccg caacaggcuc agguuccgcc      420

auagccuccg gcgucgccgu uugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aaauccgccc uacucucaac caacaaagca gucgucuccc ucucaaacgg agucucgguc      540

cucaccuuca aaguccucga ccucaaaaac uauauagaca aacaacuccu acccauacuc      600

aacaaacagu ccugcagcau auccaacauc gaaaccguga ucgaguucca acagaaaaac      660

aacagacucc ucgaaaucac ucgagaguuc uccguaaacg ccggcgucac aaccccaguc      720

ucaacauaca ugcucaccaa cagcgaacuc cuaucacuaa ucaacgacau gccuaucaca      780

aaugaucaga agaaacuaau gagcaacaac guccaaaucg uccgccaaca aucauacucc      840

aucaugugca ucauaaaaga agaaguccua gccuacgugg uccagcuacc ccucuacggc      900

guaauugaca ccccuugcug gaaacuacac acuucacccc ucugcacaac caacaccaaa      960

gaagguucaa acaucugccu cacacgaaca gaccgcggcu gguacugcga caacgccgga     1020

uccguauccu ucuuccccca agcagaaacc ugcaaaguuc aauccaaccg gguauucugc     1080

gacaccauga acucaagaac ccuucccucc gaaguaaauc uaugcaacgu cgacauauuc     1140

aacccaaaau acgacugcaa aaucaugacc uccaaaaccg augucuccag cagcgucauc     1200

accagccucg gcgccaucgu cuccugcuac ggcaaaacaa aauguacagc auccaacaaa     1260

aaccgaggca uaaucaaaac cuucuccaac gggugcgauu acgucagcaa caaaggcguc     1320

gacaccgucu ccgugggcaa cacccuauac uacgucaaca aacaagaagg caaaucacug     1380

uacguaaagg gcgaacccau caucaacuuc uaugacccuc ugguguuccc auccgaugaa     1440

uuugacgcau ccauaucuca ggucaacgaa aagaucaacc aaucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca caacgucaac gcugguaaaa gcaccaccaa caucaugauc     1560

accacaauca ucaucgucau aaucguuauc cuacucuccc uuauagcagu cggacuccuc     1620

cucuacugca aagcccgcua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  4316
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4316
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4317
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4317
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4318
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4318
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4319
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4319
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4320
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4320
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4321
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4321
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4322
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4322
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauccu caaagcaaac gcaauaacaa caauacuaac agcagucacu      180

uucugcuucg cauccggaca aaauaucaca gaagaauuuu accaauccac cugcucugcu      240

gucuccaaag gauaccuauc ugcccucaga accgguuggu auacaucugu cauaaccaua      300

gaacuaucaa acauuaaaga aaacaaaugu aacggaacag acgcaaaagu caaacuuaua      360

aaacaagaau uagacaaaua caaaaacgca gucacagaau uacaacuacu aaugcaauca      420

accccagcaa ccggaucagg auccgcaaua gcuucaggag uagcaguaug uaaaguucua      480

cacuuagaag gagaagucaa caaaauuaaa uccgcacuau uaucaaccaa caaagcaguc      540

guaucuuuau caaacggagu aucuguacuu acauucaaag uacuagaccu aaaaaauuac      600

auugauaaac aauuacuacc aauacuaaac aaacaaucau guuccaucuc uaacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agauuacuug aaaucacccg agaauuuuca      720

guaaacgcag gaguaaccac acccguaucu acauacaugc uaacaaacuc ugaacuucug      780

agccuaauaa augacaugcc aauaaccaac gaccaaaaaa aacuaauguc caacaacgua      840

caaauaguac gacaacaauc uuacucaauc augugcauaa ucaaagaaga aguacuagcu      900

uauguagucc aacuuccacu cuacggagua auagacaccc ccugcuggaa acuacacaca      960

ucaccacuau gcacaacaaa cacaaaagaa ggcucaaaca uaugccuaac aagaacugac     1020

agaggauggu auugugacaa ugcaggcucu gucucauucu uuccacaagc cgaaacaugc     1080

aaaguucaau caaaccgagu uuucugugac acaaugaacu cuagaacucu cccaucagaa     1140

gucaacuuau gcaacguuga cauauucaac ccaaaauaug acuguaaaau aaugacuucc     1200

aaaacugaug uaucauccuc cgucauaaca ucccuaggag cuauuguauc auguuacggg     1260

aaaaccaaau gcacagccuc aaacaaaaac cgcgguauca uaaaaacauu uucaaacgga     1320

ugugauuacg uaagcaauaa aggaguagac accguaucag uaggaaauac acuauacuau     1380

guaaauaaac aagaaggaaa aucacuauau gucaaaggag aaccaaucau aaauuucuau     1440

gacccacuug uauucccauc cgaugaauuu gacgcaagca uuucacaggu caacgaaaaa     1500

auaaaccaau cacuagccuu caucagaaaa ucagacgaac uacuacauaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaaca acaaucauaa uaguuaucau aguaauacua     1620

cuaucucuaa uagcugucgg acucuuacua uauugcaaag cccgauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4323
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4323
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu gaaagccaac gccauaacca caauccuuac cgcagucacc      180

uucugcuucg ccuccgguca aaacaucaca gaagaguucu accaauccac cuguuccgca      240

gucagcaaag gcuaccucuc cgcacuccga accggauggu acaccagcgu caucaccauc      300

gaacuaucca acauaaagga aaauaagugc aaugguacag augccaaggu caaacucaua      360

aagcaagaac ucgacaaaua caaaaacgcc gucaccgaac uacaacuacu aaugcaaucu      420

acccccgcaa caggcucagg uuccgccaua gccuccggcg ucgccguuug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaaa uccgcccuac ucucaaccaa caaagcaguc      540

gucucccucu caaacggagu cucgguccuc accuucaaag uccucgaccu caaaaacuau      600

auagacaaac aacuccuacc cauacucaac aaacaguccu gcagcauauc caacaucgaa      660

accgugaucg aguuccaaca gaaaaacaac agacuccucg aaaucacucg agaguucucc      720

guaaacgccg gcgucacaac cccagucuca acauacaugc ucaccaacag cgaacuccua      780

ucacuaauca acgacaugcc uaucacaaau gaucagaaga aacuaaugag caacaacguc      840

caaaucgucc gccaacaauc auacuccauc augugcauca uaaaagaaga aguccuagcc      900

uacguggucc agcuaccccu cuacggcgua auugacaccc cuugcuggaa acuacacacu      960

ucaccccucu gcacaaccaa caccaaagaa gguucaaaca ucugccucac acgaacagac     1020

cgcggcuggu acugcgacaa cgccggaucc guauccuucu ucccccaagc agaaaccugc     1080

aaaguucaau ccaaccgggu auucugcgac accaugaacu caagaacccu ucccuccgaa     1140

guaaaucuau gcaacgucga cauauucaac ccaaaauacg acugcaaaau caugaccucc     1200

aaaaccgaug ucuccagcag cgucaucacc agccucggcg ccaucgucuc cugcuacggc     1260

aaaacaaaau guacagcauc caacaaaaac cgaggcauaa ucaaaaccuu cuccaacggg     1320

ugcgauuacg ucagcaacaa aggcgucgac accgucuccg ugggcaacac ccuauacuac     1380

gucaacaaac aagaaggcaa aucacuguac guaaagggcg aacccaucau caacuucuau     1440

gacccucugg uguucccauc cgaugaauuu gacgcaucca uaucucaggu caacgaaaag     1500

aucaaccaau cccucgccuu cauacgcaaa uccgacgaac uccuacacaa cgucaacgcu     1560

gguaaaagca ccaccaacau caugaucacc acaaucauca ucgucauaau cguuauccua     1620

cucucccuua uagcagucgg acuccuccuc uacugcaaag cccgcuaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4324
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4324
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4325
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4325
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4326
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4326
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4327
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4327
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4328
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4328
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4329
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4329
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4330
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4330
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau ccucaaagca      120

aacgcaauaa caacaauacu aacagcaguc acuuucugcu ucgcauccgg acaaaauauc      180

acagaagaau uuuaccaauc caccugcucu gcugucucca aaggauaccu aucugcccuc      240

agaaccgguu gguauacauc ugucauaacc auagaacuau caaacauuaa agaaaacaaa      300

uguaacggaa cagacgcaaa agucaaacuu auaaaacaag aauuagacaa auacaaaaac      360

gcagucacag aauuacaacu acuaaugcaa ucaaccccag caaccggauc aggauccgca      420

auagcuucag gaguagcagu auguaaaguu cuacacuuag aaggagaagu caacaaaauu      480

aaauccgcac uauuaucaac caacaaagca gucguaucuu uaucaaacgg aguaucugua      540

cuuacauuca aaguacuaga ccuaaaaaau uacauugaua aacaauuacu accaauacua      600

aacaaacaau cauguuccau cucuaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaaucac ccgagaauuu ucaguaaacg caggaguaac cacacccgua      720

ucuacauaca ugcuaacaaa cucugaacuu cugagccuaa uaaaugacau gccaauaacc      780

aacgaccaaa aaaaacuaau guccaacaac guacaaauag uacgacaaca aucuuacuca      840

aucaugugca uaaucaaaga agaaguacua gcuuauguag uccaacuucc acucuacgga      900

guaauagaca cccccugcug gaaacuacac acaucaccac uaugcacaac aaacacaaaa      960

gaaggcucaa acauaugccu aacaagaacu gacagaggau gguauuguga caaugcaggc     1020

ucugucucau ucuuuccaca agccgaaaca ugcaaaguuc aaucaaaccg aguuuucugu     1080

gacacaauga acucuagaac ucucccauca gaagucaacu uaugcaacgu ugacauauuc     1140

aacccaaaau augacuguaa aauaaugacu uccaaaacug auguaucauc cuccgucaua     1200

acaucccuag gagcuauugu aucauguuac gggaaaacca aaugcacagc cucaaacaaa     1260

aaccgcggua ucauaaaaac auuuucaaac ggaugugauu acguaagcaa uaaaggagua     1320

gacaccguau caguaggaaa uacacuauac uauguaaaua aacaagaagg aaaaucacua     1380

uaugucaaag gagaaccaau cauaaauuuc uaugacccac uuguauuccc auccgaugaa     1440

uuugacgcaa gcauuucaca ggucaacgaa aaaauaaacc aaucacuagc cuucaucaga     1500

aaaucagacg aacuacuaca uaacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

acaacaauca uaauaguuau cauaguaaua cuacuaucuc uaauagcugu cggacucuua     1620

cuauauugca aagcccgaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4331
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4331
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccugaaagcc      120

aacgccauaa ccacaauccu uaccgcaguc accuucugcu ucgccuccgg ucaaaacauc      180

acagaagagu ucuaccaauc caccuguucc gcagucagca aaggcuaccu cuccgcacuc      240

cgaaccggau gguacaccag cgucaucacc aucgaacuau ccaacauaaa ggaaaauaag      300

ugcaauggua cagaugccaa ggucaaacuc auaaagcaag aacucgacaa auacaaaaac      360

gccgucaccg aacuacaacu acuaaugcaa ucuacccccg caacaggcuc agguuccgcc      420

auagccuccg gcgucgccgu uugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aaauccgccc uacucucaac caacaaagca gucgucuccc ucucaaacgg agucucgguc      540

cucaccuuca aaguccucga ccucaaaaac uauauagaca aacaacuccu acccauacuc      600

aacaaacagu ccugcagcau auccaacauc gaaaccguga ucgaguucca acagaaaaac      660

aacagacucc ucgaaaucac ucgagaguuc uccguaaacg ccggcgucac aaccccaguc      720

ucaacauaca ugcucaccaa cagcgaacuc cuaucacuaa ucaacgacau gccuaucaca      780

aaugaucaga agaaacuaau gagcaacaac guccaaaucg uccgccaaca aucauacucc      840

aucaugugca ucauaaaaga agaaguccua gccuacgugg uccagcuacc ccucuacggc      900

guaauugaca ccccuugcug gaaacuacac acuucacccc ucugcacaac caacaccaaa      960

gaagguucaa acaucugccu cacacgaaca gaccgcggcu gguacugcga caacgccgga     1020

uccguauccu ucuuccccca agcagaaacc ugcaaaguuc aauccaaccg gguauucugc     1080

gacaccauga acucaagaac ccuucccucc gaaguaaauc uaugcaacgu cgacauauuc     1140

aacccaaaau acgacugcaa aaucaugacc uccaaaaccg augucuccag cagcgucauc     1200

accagccucg gcgccaucgu cuccugcuac ggcaaaacaa aauguacagc auccaacaaa     1260

aaccgaggca uaaucaaaac cuucuccaac gggugcgauu acgucagcaa caaaggcguc     1320

gacaccgucu ccgugggcaa cacccuauac uacgucaaca aacaagaagg caaaucacug     1380

uacguaaagg gcgaacccau caucaacuuc uaugacccuc ugguguuccc auccgaugaa     1440

uuugacgcau ccauaucuca ggucaacgaa aagaucaacc aaucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca caacgucaac gcugguaaaa gcaccaccaa caucaugauc     1560

accacaauca ucaucgucau aaucguuauc cuacucuccc uuauagcagu cggacuccuc     1620

cucuacugca aagcccgcua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  4332
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4332
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4333
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4333
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4334
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4334
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4335
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4335
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4336
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4336
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4337
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4337
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4338
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4338
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau ccucaaagca      120

aacgcaauaa caacaauacu aacagcaguc acuuucugcu ucgcauccgg acaaaauauc      180

acagaagaau uuuaccaauc caccugcucu gcugucucca aaggauaccu aucugcccuc      240

agaaccgguu gguauacauc ugucauaacc auagaacuau caaacauuaa agaaaacaaa      300

uguaacggaa cagacgcaaa agucaaacuu auaaaacaag aauuagacaa auacaaaaac      360

gcagucacag aauuacaacu acuaaugcaa ucaaccccag caaccggauc aggauccgca      420

auagcuucag gaguagcagu auguaaaguu cuacacuuag aaggagaagu caacaaaauu      480

aaauccgcac uauuaucaac caacaaagca gucguaucuu uaucaaacgg aguaucugua      540

cuuacauuca aaguacuaga ccuaaaaaau uacauugaua aacaauuacu accaauacua      600

aacaaacaau cauguuccau cucuaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaaucac ccgagaauuu ucaguaaacg caggaguaac cacacccgua      720

ucuacauaca ugcuaacaaa cucugaacuu cugagccuaa uaaaugacau gccaauaacc      780

aacgaccaaa aaaaacuaau guccaacaac guacaaauag uacgacaaca aucuuacuca      840

aucaugugca uaaucaaaga agaaguacua gcuuauguag uccaacuucc acucuacgga      900

guaauagaca cccccugcug gaaacuacac acaucaccac uaugcacaac aaacacaaaa      960

gaaggcucaa acauaugccu aacaagaacu gacagaggau gguauuguga caaugcaggc     1020

ucugucucau ucuuuccaca agccgaaaca ugcaaaguuc aaucaaaccg aguuuucugu     1080

gacacaauga acucuagaac ucucccauca gaagucaacu uaugcaacgu ugacauauuc     1140

aacccaaaau augacuguaa aauaaugacu uccaaaacug auguaucauc cuccgucaua     1200

acaucccuag gagcuauugu aucauguuac gggaaaacca aaugcacagc cucaaacaaa     1260

aaccgcggua ucauaaaaac auuuucaaac ggaugugauu acguaagcaa uaaaggagua     1320

gacaccguau caguaggaaa uacacuauac uauguaaaua aacaagaagg aaaaucacua     1380

uaugucaaag gagaaccaau cauaaauuuc uaugacccac uuguauuccc auccgaugaa     1440

uuugacgcaa gcauuucaca ggucaacgaa aaaauaaacc aaucacuagc cuucaucaga     1500

aaaucagacg aacuacuaca uaacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

acaacaauca uaauaguuau cauaguaaua cuacuaucuc uaauagcugu cggacucuua     1620

cuauauugca aagcccgaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4339
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4339
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccugaaagcc      120

aacgccauaa ccacaauccu uaccgcaguc accuucugcu ucgccuccgg ucaaaacauc      180

acagaagagu ucuaccaauc caccuguucc gcagucagca aaggcuaccu cuccgcacuc      240

cgaaccggau gguacaccag cgucaucacc aucgaacuau ccaacauaaa ggaaaauaag      300

ugcaauggua cagaugccaa ggucaaacuc auaaagcaag aacucgacaa auacaaaaac      360

gccgucaccg aacuacaacu acuaaugcaa ucuacccccg caacaggcuc agguuccgcc      420

auagccuccg gcgucgccgu uugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aaauccgccc uacucucaac caacaaagca gucgucuccc ucucaaacgg agucucgguc      540

cucaccuuca aaguccucga ccucaaaaac uauauagaca aacaacuccu acccauacuc      600

aacaaacagu ccugcagcau auccaacauc gaaaccguga ucgaguucca acagaaaaac      660

aacagacucc ucgaaaucac ucgagaguuc uccguaaacg ccggcgucac aaccccaguc      720

ucaacauaca ugcucaccaa cagcgaacuc cuaucacuaa ucaacgacau gccuaucaca      780

aaugaucaga agaaacuaau gagcaacaac guccaaaucg uccgccaaca aucauacucc      840

aucaugugca ucauaaaaga agaaguccua gccuacgugg uccagcuacc ccucuacggc      900

guaauugaca ccccuugcug gaaacuacac acuucacccc ucugcacaac caacaccaaa      960

gaagguucaa acaucugccu cacacgaaca gaccgcggcu gguacugcga caacgccgga     1020

uccguauccu ucuuccccca agcagaaacc ugcaaaguuc aauccaaccg gguauucugc     1080

gacaccauga acucaagaac ccuucccucc gaaguaaauc uaugcaacgu cgacauauuc     1140

aacccaaaau acgacugcaa aaucaugacc uccaaaaccg augucuccag cagcgucauc     1200

accagccucg gcgccaucgu cuccugcuac ggcaaaacaa aauguacagc auccaacaaa     1260

aaccgaggca uaaucaaaac cuucuccaac gggugcgauu acgucagcaa caaaggcguc     1320

gacaccgucu ccgugggcaa cacccuauac uacgucaaca aacaagaagg caaaucacug     1380

uacguaaagg gcgaacccau caucaacuuc uaugacccuc ugguguuccc auccgaugaa     1440

uuugacgcau ccauaucuca ggucaacgaa aagaucaacc aaucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca caacgucaac gcugguaaaa gcaccaccaa caucaugauc     1560

accacaauca ucaucgucau aaucguuauc cuacucuccc uuauagcagu cggacuccuc     1620

cucuacugca aagcccgcua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4340
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4340
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4341
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4341
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4342
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4342
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4343
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4343
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4344
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4344
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4345
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4345
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4346
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4346
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauccucaa agcaaacgca      120

auaacaacaa uacuaacagc agucacuuuc ugcuucgcau ccggacaaaa uaucacagaa      180

gaauuuuacc aauccaccug cucugcuguc uccaaaggau accuaucugc ccucagaacc      240

gguugguaua caucugucau aaccauagaa cuaucaaaca uuaaagaaaa caaauguaac      300

ggaacagacg caaaagucaa acuuauaaaa caagaauuag acaaauacaa aaacgcaguc      360

acagaauuac aacuacuaau gcaaucaacc ccagcaaccg gaucaggauc cgcaauagcu      420

ucaggaguag caguauguaa aguucuacac uuagaaggag aagucaacaa aauuaaaucc      480

gcacuauuau caaccaacaa agcagucgua ucuuuaucaa acggaguauc uguacuuaca      540

uucaaaguac uagaccuaaa aaauuacauu gauaaacaau uacuaccaau acuaaacaaa      600

caaucauguu ccaucucuaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa ucacccgaga auuuucagua aacgcaggag uaaccacacc cguaucuaca      720

uacaugcuaa caaacucuga acuucugagc cuaauaaaug acaugccaau aaccaacgac      780

caaaaaaaac uaauguccaa caacguacaa auaguacgac aacaaucuua cucaaucaug      840

ugcauaauca aagaagaagu acuagcuuau guaguccaac uuccacucua cggaguaaua      900

gacacccccu gcuggaaacu acacacauca ccacuaugca caacaaacac aaaagaaggc      960

ucaaacauau gccuaacaag aacugacaga ggaugguauu gugacaaugc aggcucuguc     1020

ucauucuuuc cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacaca     1080

augaacucua gaacucuccc aucagaaguc aacuuaugca acguugacau auucaaccca     1140

aaauaugacu guaaaauaau gacuuccaaa acugauguau cauccuccgu cauaacaucc     1200

cuaggagcua uuguaucaug uuacgggaaa accaaaugca cagccucaaa caaaaaccgc     1260

gguaucauaa aaacauuuuc aaacggaugu gauuacguaa gcaauaaagg aguagacacc     1320

guaucaguag gaaauacacu auacuaugua aauaaacaag aaggaaaauc acuauauguc     1380

aaaggagaac caaucauaaa uuucuaugac ccacuuguau ucccauccga ugaauuugac     1440

gcaagcauuu cacaggucaa cgaaaaaaua aaccaaucac uagccuucau cagaaaauca     1500

gacgaacuac uacauaacgu aaacgccgga aaaucaacaa ccaacauaau gauaacaaca     1560

aucauaauag uuaucauagu aauacuacua ucucuaauag cugucggacu cuuacuauau     1620

ugcaaagccc gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4347
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4347
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccugaa agccaacgcc      120

auaaccacaa uccuuaccgc agucaccuuc ugcuucgccu ccggucaaaa caucacagaa      180

gaguucuacc aauccaccug uuccgcaguc agcaaaggcu accucuccgc acuccgaacc      240

ggaugguaca ccagcgucau caccaucgaa cuauccaaca uaaaggaaaa uaagugcaau      300

gguacagaug ccaaggucaa acucauaaag caagaacucg acaaauacaa aaacgccguc      360

accgaacuac aacuacuaau gcaaucuacc cccgcaacag gcucagguuc cgccauagcc      420

uccggcgucg ccguuugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agcagucguc ucccucucaa acggagucuc gguccucacc      540

uucaaagucc ucgaccucaa aaacuauaua gacaaacaac uccuacccau acucaacaaa      600

caguccugca gcauauccaa caucgaaacc gugaucgagu uccaacagaa aaacaacaga      660

cuccucgaaa ucacucgaga guucuccgua aacgccggcg ucacaacccc agucucaaca      720

uacaugcuca ccaacagcga acuccuauca cuaaucaacg acaugccuau cacaaaugau      780

cagaagaaac uaaugagcaa caacguccaa aucguccgcc aacaaucaua cuccaucaug      840

ugcaucauaa aagaagaagu ccuagccuac gugguccagc uaccccucua cggcguaauu      900

gacaccccuu gcuggaaacu acacacuuca ccccucugca caaccaacac caaagaaggu      960

ucaaacaucu gccucacacg aacagaccgc ggcugguacu gcgacaacgc cggauccgua     1020

uccuucuucc cccaagcaga aaccugcaaa guucaaucca accggguauu cugcgacacc     1080

augaacucaa gaacccuucc cuccgaagua aaucuaugca acgucgacau auucaaccca     1140

aaauacgacu gcaaaaucau gaccuccaaa accgaugucu ccagcagcgu caucaccagc     1200

cucggcgcca ucgucuccug cuacggcaaa acaaaaugua cagcauccaa caaaaaccga     1260

ggcauaauca aaaccuucuc caacgggugc gauuacguca gcaacaaagg cgucgacacc     1320

gucuccgugg gcaacacccu auacuacguc aacaaacaag aaggcaaauc acuguacgua     1380

aagggcgaac ccaucaucaa cuucuaugac ccucuggugu ucccauccga ugaauuugac     1440

gcauccauau cucaggucaa cgaaaagauc aaccaauccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu caacgcuggu aaaagcacca ccaacaucau gaucaccaca     1560

aucaucaucg ucauaaucgu uauccuacuc ucccuuauag cagucggacu ccuccucuac     1620

ugcaaagccc gcuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  4348
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4348
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4349
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4349
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4350
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4350
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4351
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4351
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4352
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4352
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4353
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4353
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4354
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4354
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauccucaaa      120

gcaaacgcaa uaacaacaau acuaacagca gucacuuucu gcuucgcauc cggacaaaau      180

aucacagaag aauuuuacca auccaccugc ucugcugucu ccaaaggaua ccuaucugcc      240

cucagaaccg guugguauac aucugucaua accauagaac uaucaaacau uaaagaaaac      300

aaauguaacg gaacagacgc aaaagucaaa cuuauaaaac aagaauuaga caaauacaaa      360

aacgcaguca cagaauuaca acuacuaaug caaucaaccc cagcaaccgg aucaggaucc      420

gcaauagcuu caggaguagc aguauguaaa guucuacacu uagaaggaga agucaacaaa      480

auuaaauccg cacuauuauc aaccaacaaa gcagucguau cuuuaucaaa cggaguaucu      540

guacuuacau ucaaaguacu agaccuaaaa aauuacauug auaaacaauu acuaccaaua      600

cuaaacaaac aaucauguuc caucucuaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau cacccgagaa uuuucaguaa acgcaggagu aaccacaccc      720

guaucuacau acaugcuaac aaacucugaa cuucugagcc uaauaaauga caugccaaua      780

accaacgacc aaaaaaaacu aauguccaac aacguacaaa uaguacgaca acaaucuuac      840

ucaaucaugu gcauaaucaa agaagaagua cuagcuuaug uaguccaacu uccacucuac      900

ggaguaauag acacccccug cuggaaacua cacacaucac cacuaugcac aacaaacaca      960

aaagaaggcu caaacauaug ccuaacaaga acugacagag gaugguauug ugacaaugca     1020

ggcucugucu cauucuuucc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacaa ugaacucuag aacucuccca ucagaaguca acuuaugcaa cguugacaua     1140

uucaacccaa aauaugacug uaaaauaaug acuuccaaaa cugauguauc auccuccguc     1200

auaacauccc uaggagcuau uguaucaugu uacgggaaaa ccaaaugcac agccucaaac     1260

aaaaaccgcg guaucauaaa aacauuuuca aacggaugug auuacguaag caauaaagga     1320

guagacaccg uaucaguagg aaauacacua uacuauguaa auaaacaaga aggaaaauca     1380

cuauauguca aaggagaacc aaucauaaau uucuaugacc cacuuguauu cccauccgau     1440

gaauuugacg caagcauuuc acaggucaac gaaaaaauaa accaaucacu agccuucauc     1500

agaaaaucag acgaacuacu acauaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaacaacaa ucauaauagu uaucauagua auacuacuau cucuaauagc ugucggacuc     1620

uuacuauauu gcaaagcccg auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4355
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4355
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccugaaa      120

gccaacgcca uaaccacaau ccuuaccgca gucaccuucu gcuucgccuc cggucaaaac      180

aucacagaag aguucuacca auccaccugu uccgcaguca gcaaaggcua ccucuccgca      240

cuccgaaccg gaugguacac cagcgucauc accaucgaac uauccaacau aaaggaaaau      300

aagugcaaug guacagaugc caaggucaaa cucauaaagc aagaacucga caaauacaaa      360

aacgccguca ccgaacuaca acuacuaaug caaucuaccc ccgcaacagg cucagguucc      420

gccauagccu ccggcgucgc cguuugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gcagucgucu cccucucaaa cggagucucg      540

guccucaccu ucaaaguccu cgaccucaaa aacuauauag acaaacaacu ccuacccaua      600

cucaacaaac aguccugcag cauauccaac aucgaaaccg ugaucgaguu ccaacagaaa      660

aacaacagac uccucgaaau cacucgagag uucuccguaa acgccggcgu cacaacccca      720

gucucaacau acaugcucac caacagcgaa cuccuaucac uaaucaacga caugccuauc      780

acaaaugauc agaagaaacu aaugagcaac aacguccaaa ucguccgcca acaaucauac      840

uccaucaugu gcaucauaaa agaagaaguc cuagccuacg ugguccagcu accccucuac      900

ggcguaauug acaccccuug cuggaaacua cacacuucac cccucugcac aaccaacacc      960

aaagaagguu caaacaucug ccucacacga acagaccgcg gcugguacug cgacaacgcc     1020

ggauccguau ccuucuuccc ccaagcagaa accugcaaag uucaauccaa ccggguauuc     1080

ugcgacacca ugaacucaag aacccuuccc uccgaaguaa aucuaugcaa cgucgacaua     1140

uucaacccaa aauacgacug caaaaucaug accuccaaaa ccgaugucuc cagcagcguc     1200

aucaccagcc ucggcgccau cgucuccugc uacggcaaaa caaaauguac agcauccaac     1260

aaaaaccgag gcauaaucaa aaccuucucc aacgggugcg auuacgucag caacaaaggc     1320

gucgacaccg ucuccguggg caacacccua uacuacguca acaaacaaga aggcaaauca     1380

cuguacguaa agggcgaacc caucaucaac uucuaugacc cucugguguu cccauccgau     1440

gaauuugacg cauccauauc ucaggucaac gaaaagauca accaaucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acacaacguc aacgcuggua aaagcaccac caacaucaug     1560

aucaccacaa ucaucaucgu cauaaucguu auccuacucu cccuuauagc agucggacuc     1620

cuccucuacu gcaaagcccg cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  4356
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4356
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4357
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4357
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4358
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4358
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4359
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4359
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4360
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4360
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4361
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4361
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4362
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4362
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauccucaa agcaaacgca      120

auaacaacaa uacuaacagc agucacuuuc ugcuucgcau ccggacaaaa uaucacagaa      180

gaauuuuacc aauccaccug cucugcuguc uccaaaggau accuaucugc ccucagaacc      240

gguugguaua caucugucau aaccauagaa cuaucaaaca uuaaagaaaa caaauguaac      300

ggaacagacg caaaagucaa acuuauaaaa caagaauuag acaaauacaa aaacgcaguc      360

acagaauuac aacuacuaau gcaaucaacc ccagcaaccg gaucaggauc cgcaauagcu      420

ucaggaguag caguauguaa aguucuacac uuagaaggag aagucaacaa aauuaaaucc      480

gcacuauuau caaccaacaa agcagucgua ucuuuaucaa acggaguauc uguacuuaca      540

uucaaaguac uagaccuaaa aaauuacauu gauaaacaau uacuaccaau acuaaacaaa      600

caaucauguu ccaucucuaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa ucacccgaga auuuucagua aacgcaggag uaaccacacc cguaucuaca      720

uacaugcuaa caaacucuga acuucugagc cuaauaaaug acaugccaau aaccaacgac      780

caaaaaaaac uaauguccaa caacguacaa auaguacgac aacaaucuua cucaaucaug      840

ugcauaauca aagaagaagu acuagcuuau guaguccaac uuccacucua cggaguaaua      900

gacacccccu gcuggaaacu acacacauca ccacuaugca caacaaacac aaaagaaggc      960

ucaaacauau gccuaacaag aacugacaga ggaugguauu gugacaaugc aggcucuguc     1020

ucauucuuuc cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacaca     1080

augaacucua gaacucuccc aucagaaguc aacuuaugca acguugacau auucaaccca     1140

aaauaugacu guaaaauaau gacuuccaaa acugauguau cauccuccgu cauaacaucc     1200

cuaggagcua uuguaucaug uuacgggaaa accaaaugca cagccucaaa caaaaaccgc     1260

gguaucauaa aaacauuuuc aaacggaugu gauuacguaa gcaauaaagg aguagacacc     1320

guaucaguag gaaauacacu auacuaugua aauaaacaag aaggaaaauc acuauauguc     1380

aaaggagaac caaucauaaa uuucuaugac ccacuuguau ucccauccga ugaauuugac     1440

gcaagcauuu cacaggucaa cgaaaaaaua aaccaaucac uagccuucau cagaaaauca     1500

gacgaacuac uacauaacgu aaacgccgga aaaucaacaa ccaacauaau gauaacaaca     1560

aucauaauag uuaucauagu aauacuacua ucucuaauag cugucggacu cuuacuauau     1620

ugcaaagccc gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4363
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4363
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccugaa agccaacgcc      120

auaaccacaa uccuuaccgc agucaccuuc ugcuucgccu ccggucaaaa caucacagaa      180

gaguucuacc aauccaccug uuccgcaguc agcaaaggcu accucuccgc acuccgaacc      240

ggaugguaca ccagcgucau caccaucgaa cuauccaaca uaaaggaaaa uaagugcaau      300

gguacagaug ccaaggucaa acucauaaag caagaacucg acaaauacaa aaacgccguc      360

accgaacuac aacuacuaau gcaaucuacc cccgcaacag gcucagguuc cgccauagcc      420

uccggcgucg ccguuugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agcagucguc ucccucucaa acggagucuc gguccucacc      540

uucaaagucc ucgaccucaa aaacuauaua gacaaacaac uccuacccau acucaacaaa      600

caguccugca gcauauccaa caucgaaacc gugaucgagu uccaacagaa aaacaacaga      660

cuccucgaaa ucacucgaga guucuccgua aacgccggcg ucacaacccc agucucaaca      720

uacaugcuca ccaacagcga acuccuauca cuaaucaacg acaugccuau cacaaaugau      780

cagaagaaac uaaugagcaa caacguccaa aucguccgcc aacaaucaua cuccaucaug      840

ugcaucauaa aagaagaagu ccuagccuac gugguccagc uaccccucua cggcguaauu      900

gacaccccuu gcuggaaacu acacacuuca ccccucugca caaccaacac caaagaaggu      960

ucaaacaucu gccucacacg aacagaccgc ggcugguacu gcgacaacgc cggauccgua     1020

uccuucuucc cccaagcaga aaccugcaaa guucaaucca accggguauu cugcgacacc     1080

augaacucaa gaacccuucc cuccgaagua aaucuaugca acgucgacau auucaaccca     1140

aaauacgacu gcaaaaucau gaccuccaaa accgaugucu ccagcagcgu caucaccagc     1200

cucggcgcca ucgucuccug cuacggcaaa acaaaaugua cagcauccaa caaaaaccga     1260

ggcauaauca aaaccuucuc caacgggugc gauuacguca gcaacaaagg cgucgacacc     1320

gucuccgugg gcaacacccu auacuacguc aacaaacaag aaggcaaauc acuguacgua     1380

aagggcgaac ccaucaucaa cuucuaugac ccucuggugu ucccauccga ugaauuugac     1440

gcauccauau cucaggucaa cgaaaagauc aaccaauccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu caacgcuggu aaaagcacca ccaacaucau gaucaccaca     1560

aucaucaucg ucauaaucgu uauccuacuc ucccuuauag cagucggacu ccuccucuac     1620

ugcaaagccc gcuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  4364
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4364
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4365
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4365
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4366
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4366
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4367
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4367
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4368
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4368
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4369
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4369
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4370
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4370
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucaucc ucaaagcaaa cgcaauaaca acaauacuaa cagcagucac uuucugcuuc      240

gcauccggac aaaauaucac agaagaauuu uaccaaucca ccugcucugc ugucuccaaa      300

ggauaccuau cugcccucag aaccgguugg uauacaucug ucauaaccau agaacuauca      360

aacauuaaag aaaacaaaug uaacggaaca gacgcaaaag ucaaacuuau aaaacaagaa      420

uuagacaaau acaaaaacgc agucacagaa uuacaacuac uaaugcaauc aaccccagca      480

accggaucag gauccgcaau agcuucagga guagcaguau guaaaguucu acacuuagaa      540

ggagaaguca acaaaauuaa auccgcacua uuaucaacca acaaagcagu cguaucuuua      600

ucaaacggag uaucuguacu uacauucaaa guacuagacc uaaaaaauua cauugauaaa      660

caauuacuac caauacuaaa caaacaauca uguuccaucu cuaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaaucaccc gagaauuuuc aguaaacgca      780

ggaguaacca cacccguauc uacauacaug cuaacaaacu cugaacuucu gagccuaaua      840

aaugacaugc caauaaccaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

cgacaacaau cuuacucaau caugugcaua aucaaagaag aaguacuagc uuauguaguc      960

caacuuccac ucuacggagu aauagacacc cccugcugga aacuacacac aucaccacua     1020

ugcacaacaa acacaaaaga aggcucaaac auaugccuaa caagaacuga cagaggaugg     1080

uauugugaca augcaggcuc ugucucauuc uuuccacaag ccgaaacaug caaaguucaa     1140

ucaaaccgag uuuucuguga cacaaugaac ucuagaacuc ucccaucaga agucaacuua     1200

ugcaacguug acauauucaa cccaaaauau gacuguaaaa uaaugacuuc caaaacugau     1260

guaucauccu ccgucauaac aucccuagga gcuauuguau cauguuacgg gaaaaccaaa     1320

ugcacagccu caaacaaaaa ccgcgguauc auaaaaacau uuucaaacgg augugauuac     1380

guaagcaaua aaggaguaga caccguauca guaggaaaua cacuauacua uguaaauaaa     1440

caagaaggaa aaucacuaua ugucaaagga gaaccaauca uaaauuucua ugacccacuu     1500

guauucccau ccgaugaauu ugacgcaagc auuucacagg ucaacgaaaa aauaaaccaa     1560

ucacuagccu ucaucagaaa aucagacgaa cuacuacaua acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac aacaaucaua auaguuauca uaguaauacu acuaucucua     1680

auagcugucg gacucuuacu auauugcaaa gcccgauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4371
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4371
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc ugaaagccaa cgccauaacc acaauccuua ccgcagucac cuucugcuuc      240

gccuccgguc aaaacaucac agaagaguuc uaccaaucca ccuguuccgc agucagcaaa      300

ggcuaccucu ccgcacuccg aaccggaugg uacaccagcg ucaucaccau cgaacuaucc      360

aacauaaagg aaaauaagug caaugguaca gaugccaagg ucaaacucau aaagcaagaa      420

cucgacaaau acaaaaacgc cgucaccgaa cuacaacuac uaaugcaauc uacccccgca      480

acaggcucag guuccgccau agccuccggc gucgccguuu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa auccgcccua cucucaacca acaaagcagu cgucucccuc      600

ucaaacggag ucucgguccu caccuucaaa guccucgacc ucaaaaacua uauagacaaa      660

caacuccuac ccauacucaa caaacagucc ugcagcauau ccaacaucga aaccgugauc      720

gaguuccaac agaaaaacaa cagacuccuc gaaaucacuc gagaguucuc cguaaacgcc      780

ggcgucacaa ccccagucuc aacauacaug cucaccaaca gcgaacuccu aucacuaauc      840

aacgacaugc cuaucacaaa ugaucagaag aaacuaauga gcaacaacgu ccaaaucguc      900

cgccaacaau cauacuccau caugugcauc auaaaagaag aaguccuagc cuacgugguc      960

cagcuacccc ucuacggcgu aauugacacc ccuugcugga aacuacacac uucaccccuc     1020

ugcacaacca acaccaaaga agguucaaac aucugccuca cacgaacaga ccgcggcugg     1080

uacugcgaca acgccggauc cguauccuuc uucccccaag cagaaaccug caaaguucaa     1140

uccaaccggg uauucugcga caccaugaac ucaagaaccc uucccuccga aguaaaucua     1200

ugcaacgucg acauauucaa cccaaaauac gacugcaaaa ucaugaccuc caaaaccgau     1260

gucuccagca gcgucaucac cagccucggc gccaucgucu ccugcuacgg caaaacaaaa     1320

uguacagcau ccaacaaaaa ccgaggcaua aucaaaaccu ucuccaacgg gugcgauuac     1380

gucagcaaca aaggcgucga caccgucucc gugggcaaca cccuauacua cgucaacaaa     1440

caagaaggca aaucacugua cguaaagggc gaacccauca ucaacuucua ugacccucug     1500

guguucccau ccgaugaauu ugacgcaucc auaucucagg ucaacgaaaa gaucaaccaa     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaca acgucaacgc ugguaaaagc     1620

accaccaaca ucaugaucac cacaaucauc aucgucauaa ucguuauccu acucucccuu     1680

auagcagucg gacuccuccu cuacugcaaa gcccgcuaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  4372
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4372
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4373
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4373
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4374
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4374
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4375
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4375
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4376
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4376
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4377
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4377
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4378
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4378
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uccucaaagc aaacgcaaua acaacaauac      120

uaacagcagu cacuuucugc uucgcauccg gacaaaauau cacagaagaa uuuuaccaau      180

ccaccugcuc ugcugucucc aaaggauacc uaucugcccu cagaaccggu ugguauacau      240

cugucauaac cauagaacua ucaaacauua aagaaaacaa auguaacgga acagacgcaa      300

aagucaaacu uauaaaacaa gaauuagaca aauacaaaaa cgcagucaca gaauuacaac      360

uacuaaugca aucaacccca gcaaccggau caggauccgc aauagcuuca ggaguagcag      420

uauguaaagu ucuacacuua gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa      480

ccaacaaagc agucguaucu uuaucaaacg gaguaucugu acuuacauuc aaaguacuag      540

accuaaaaaa uuacauugau aaacaauuac uaccaauacu aaacaaacaa ucauguucca      600

ucucuaacau agaaacagua auagaauuuc aacaaaaaaa uaacagauua cuugaaauca      660

cccgagaauu uucaguaaac gcaggaguaa ccacacccgu aucuacauac augcuaacaa      720

acucugaacu ucugagccua auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaaua guacgacaac aaucuuacuc aaucaugugc auaaucaaag      840

aagaaguacu agcuuaugua guccaacuuc cacucuacgg aguaauagac acccccugcu      900

ggaaacuaca cacaucacca cuaugcacaa caaacacaaa agaaggcuca aacauaugcc      960

uaacaagaac ugacagagga ugguauugug acaaugcagg cucugucuca uucuuuccac     1020

aagccgaaac augcaaaguu caaucaaacc gaguuuucug ugacacaaug aacucuagaa     1080

cucucccauc agaagucaac uuaugcaacg uugacauauu caacccaaaa uaugacugua     1140

aaauaaugac uuccaaaacu gauguaucau ccuccgucau aacaucccua ggagcuauug     1200

uaucauguua cgggaaaacc aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa     1260

cauuuucaaa cggaugugau uacguaagca auaaaggagu agacaccgua ucaguaggaa     1320

auacacuaua cuauguaaau aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa     1380

ucauaaauuu cuaugaccca cuuguauucc cauccgauga auuugacgca agcauuucac     1440

aggucaacga aaaaauaaac caaucacuag ccuucaucag aaaaucagac gaacuacuac     1500

auaacguaaa cgccggaaaa ucaacaacca acauaaugau aacaacaauc auaauaguua     1560

ucauaguaau acuacuaucu cuaauagcug ucggacucuu acuauauugc aaagcccgau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4379
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4379
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccugaaagc caacgccaua accacaaucc      120

uuaccgcagu caccuucugc uucgccuccg gucaaaacau cacagaagag uucuaccaau      180

ccaccuguuc cgcagucagc aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca      240

gcgucaucac caucgaacua uccaacauaa aggaaaauaa gugcaauggu acagaugcca      300

aggucaaacu cauaaagcaa gaacucgaca aauacaaaaa cgccgucacc gaacuacaac      360

uacuaaugca aucuaccccc gcaacaggcu cagguuccgc cauagccucc ggcgucgccg      420

uuugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc agucgucucc cucucaaacg gagucucggu ccucaccuuc aaaguccucg      540

accucaaaaa cuauauagac aaacaacucc uacccauacu caacaaacag uccugcagca      600

uauccaacau cgaaaccgug aucgaguucc aacagaaaaa caacagacuc cucgaaauca      660

cucgagaguu cuccguaaac gccggcguca caaccccagu cucaacauac augcucacca      720

acagcgaacu ccuaucacua aucaacgaca ugccuaucac aaaugaucag aagaaacuaa      780

ugagcaacaa cguccaaauc guccgccaac aaucauacuc caucaugugc aucauaaaag      840

aagaaguccu agccuacgug guccagcuac cccucuacgg cguaauugac accccuugcu      900

ggaaacuaca cacuucaccc cucugcacaa ccaacaccaa agaagguuca aacaucugcc      960

ucacacgaac agaccgcggc ugguacugcg acaacgccgg auccguaucc uucuuccccc     1020

aagcagaaac cugcaaaguu caauccaacc ggguauucug cgacaccaug aacucaagaa     1080

cccuucccuc cgaaguaaau cuaugcaacg ucgacauauu caacccaaaa uacgacugca     1140

aaaucaugac cuccaaaacc gaugucucca gcagcgucau caccagccuc ggcgccaucg     1200

ucuccugcua cggcaaaaca aaauguacag cauccaacaa aaaccgaggc auaaucaaaa     1260

ccuucuccaa cgggugcgau uacgucagca acaaaggcgu cgacaccguc uccgugggca     1320

acacccuaua cuacgucaac aaacaagaag gcaaaucacu guacguaaag ggcgaaccca     1380

ucaucaacuu cuaugacccu cugguguucc cauccgauga auuugacgca uccauaucuc     1440

aggucaacga aaagaucaac caaucccucg ccuucauacg caaauccgac gaacuccuac     1500

acaacgucaa cgcugguaaa agcaccacca acaucaugau caccacaauc aucaucguca     1560

uaaucguuau ccuacucucc cuuauagcag ucggacuccu ccucuacugc aaagcccgcu     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4380
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4380
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4381
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4381
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4382
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4382
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4383
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4383
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4384
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4384
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4385
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4385
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4386
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4386
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucaucc ucaaagcaaa cgcaauaaca acaauacuaa cagcagucac uuucugcuuc      240

gcauccggac aaaauaucac agaagaauuu uaccaaucca ccugcucugc ugucuccaaa      300

ggauaccuau cugcccucag aaccgguugg uauacaucug ucauaaccau agaacuauca      360

aacauuaaag aaaacaaaug uaacggaaca gacgcaaaag ucaaacuuau aaaacaagaa      420

uuagacaaau acaaaaacgc agucacagaa uuacaacuac uaaugcaauc aaccccagca      480

accggaucag gauccgcaau agcuucagga guagcaguau guaaaguucu acacuuagaa      540

ggagaaguca acaaaauuaa auccgcacua uuaucaacca acaaagcagu cguaucuuua      600

ucaaacggag uaucuguacu uacauucaaa guacuagacc uaaaaaauua cauugauaaa      660

caauuacuac caauacuaaa caaacaauca uguuccaucu cuaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaaucaccc gagaauuuuc aguaaacgca      780

ggaguaacca cacccguauc uacauacaug cuaacaaacu cugaacuucu gagccuaaua      840

aaugacaugc caauaaccaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

cgacaacaau cuuacucaau caugugcaua aucaaagaag aaguacuagc uuauguaguc      960

caacuuccac ucuacggagu aauagacacc cccugcugga aacuacacac aucaccacua     1020

ugcacaacaa acacaaaaga aggcucaaac auaugccuaa caagaacuga cagaggaugg     1080

uauugugaca augcaggcuc ugucucauuc uuuccacaag ccgaaacaug caaaguucaa     1140

ucaaaccgag uuuucuguga cacaaugaac ucuagaacuc ucccaucaga agucaacuua     1200

ugcaacguug acauauucaa cccaaaauau gacuguaaaa uaaugacuuc caaaacugau     1260

guaucauccu ccgucauaac aucccuagga gcuauuguau cauguuacgg gaaaaccaaa     1320

ugcacagccu caaacaaaaa ccgcgguauc auaaaaacau uuucaaacgg augugauuac     1380

guaagcaaua aaggaguaga caccguauca guaggaaaua cacuauacua uguaaauaaa     1440

caagaaggaa aaucacuaua ugucaaagga gaaccaauca uaaauuucua ugacccacuu     1500

guauucccau ccgaugaauu ugacgcaagc auuucacagg ucaacgaaaa aauaaaccaa     1560

ucacuagccu ucaucagaaa aucagacgaa cuacuacaua acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac aacaaucaua auaguuauca uaguaauacu acuaucucua     1680

auagcugucg gacucuuacu auauugcaaa gcccgauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4387
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4387
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc ugaaagccaa cgccauaacc acaauccuua ccgcagucac cuucugcuuc      240

gccuccgguc aaaacaucac agaagaguuc uaccaaucca ccuguuccgc agucagcaaa      300

ggcuaccucu ccgcacuccg aaccggaugg uacaccagcg ucaucaccau cgaacuaucc      360

aacauaaagg aaaauaagug caaugguaca gaugccaagg ucaaacucau aaagcaagaa      420

cucgacaaau acaaaaacgc cgucaccgaa cuacaacuac uaaugcaauc uacccccgca      480

acaggcucag guuccgccau agccuccggc gucgccguuu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa auccgcccua cucucaacca acaaagcagu cgucucccuc      600

ucaaacggag ucucgguccu caccuucaaa guccucgacc ucaaaaacua uauagacaaa      660

caacuccuac ccauacucaa caaacagucc ugcagcauau ccaacaucga aaccgugauc      720

gaguuccaac agaaaaacaa cagacuccuc gaaaucacuc gagaguucuc cguaaacgcc      780

ggcgucacaa ccccagucuc aacauacaug cucaccaaca gcgaacuccu aucacuaauc      840

aacgacaugc cuaucacaaa ugaucagaag aaacuaauga gcaacaacgu ccaaaucguc      900

cgccaacaau cauacuccau caugugcauc auaaaagaag aaguccuagc cuacgugguc      960

cagcuacccc ucuacggcgu aauugacacc ccuugcugga aacuacacac uucaccccuc     1020

ugcacaacca acaccaaaga agguucaaac aucugccuca cacgaacaga ccgcggcugg     1080

uacugcgaca acgccggauc cguauccuuc uucccccaag cagaaaccug caaaguucaa     1140

uccaaccggg uauucugcga caccaugaac ucaagaaccc uucccuccga aguaaaucua     1200

ugcaacgucg acauauucaa cccaaaauac gacugcaaaa ucaugaccuc caaaaccgau     1260

gucuccagca gcgucaucac cagccucggc gccaucgucu ccugcuacgg caaaacaaaa     1320

uguacagcau ccaacaaaaa ccgaggcaua aucaaaaccu ucuccaacgg gugcgauuac     1380

gucagcaaca aaggcgucga caccgucucc gugggcaaca cccuauacua cgucaacaaa     1440

caagaaggca aaucacugua cguaaagggc gaacccauca ucaacuucua ugacccucug     1500

guguucccau ccgaugaauu ugacgcaucc auaucucagg ucaacgaaaa gaucaaccaa     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaca acgucaacgc ugguaaaagc     1620

accaccaaca ucaugaucac cacaaucauc aucgucauaa ucguuauccu acucucccuu     1680

auagcagucg gacuccuccu cuacugcaaa gcccgcuaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4388
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4388
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4389
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4389
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      480

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      540

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1020

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1140

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1260

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1320

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1380

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4390
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4390
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4391
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4391
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      480

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      540

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      600

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      720

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      780

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      840

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua      900

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca      960

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc     1020

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1080

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1140

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1200

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1260

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1320

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1380

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1440

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1500

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1560

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1620

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4392
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4392
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4393
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4393
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      480

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      540

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      600

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      720

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      780

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      840

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug      900

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu      960

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga     1020

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1080

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1140

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1200

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1260

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1320

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1380

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1440

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1500

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1620

cugaucgccg ugggccuccu gcuguacugc aaagcuagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4394
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4394
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaauuacuca uccucaaagc aaacgcaaua acaacaauac uaacagcagu cacuuucugc      180

uucgcauccg gacaaaauau cacagaagaa uuuuaccaau ccaccugcuc ugcugucucc      240

aaaggauacc uaucugcccu cagaaccggu ugguauacau cugucauaac cauagaacua      300

ucaaacauua aagaaaacaa auguaacgga acagacgcaa aagucaaacu uauaaaacaa      360

gaauuagaca aauacaaaaa cgcagucaca gaauuacaac uacuaaugca aucaacccca      420

gcaaccggau caggauccgc aauagcuuca ggaguagcag uauguaaagu ucuacacuua      480

gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa ccaacaaagc agucguaucu      540

uuaucaaacg gaguaucugu acuuacauuc aaaguacuag accuaaaaaa uuacauugau      600

aaacaauuac uaccaauacu aaacaaacaa ucauguucca ucucuaacau agaaacagua      660

auagaauuuc aacaaaaaaa uaacagauua cuugaaauca cccgagaauu uucaguaaac      720

gcaggaguaa ccacacccgu aucuacauac augcuaacaa acucugaacu ucugagccua      780

auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa uguccaacaa cguacaaaua      840

guacgacaac aaucuuacuc aaucaugugc auaaucaaag aagaaguacu agcuuaugua      900

guccaacuuc cacucuacgg aguaauagac acccccugcu ggaaacuaca cacaucacca      960

cuaugcacaa caaacacaaa agaaggcuca aacauaugcc uaacaagaac ugacagagga     1020

ugguauugug acaaugcagg cucugucuca uucuuuccac aagccgaaac augcaaaguu     1080

caaucaaacc gaguuuucug ugacacaaug aacucuagaa cucucccauc agaagucaac     1140

uuaugcaacg uugacauauu caacccaaaa uaugacugua aaauaaugac uuccaaaacu     1200

gauguaucau ccuccgucau aacaucccua ggagcuauug uaucauguua cgggaaaacc     1260

aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa cauuuucaaa cggaugugau     1320

uacguaagca auaaaggagu agacaccgua ucaguaggaa auacacuaua cuauguaaau     1380

aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa ucauaaauuu cuaugaccca     1440

cuuguauucc cauccgauga auuugacgca agcauuucac aggucaacga aaaaauaaac     1500

caaucacuag ccuucaucag aaaaucagac gaacuacuac auaacguaaa cgccggaaaa     1560

ucaacaacca acauaaugau aacaacaauc auaauaguua ucauaguaau acuacuaucu     1620

cuaauagcug ucggacucuu acuauauugc aaagcccgau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4395
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4395
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuaa uccugaaagc caacgccaua accacaaucc uuaccgcagu caccuucugc      180

uucgccuccg gucaaaacau cacagaagag uucuaccaau ccaccuguuc cgcagucagc      240

aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca gcgucaucac caucgaacua      300

uccaacauaa aggaaaauaa gugcaauggu acagaugcca aggucaaacu cauaaagcaa      360

gaacucgaca aauacaaaaa cgccgucacc gaacuacaac uacuaaugca aucuaccccc      420

gcaacaggcu cagguuccgc cauagccucc ggcgucgccg uuugcaaagu ccuccaccuc      480

gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa ccaacaaagc agucgucucc      540

cucucaaacg gagucucggu ccucaccuuc aaaguccucg accucaaaaa cuauauagac      600

aaacaacucc uacccauacu caacaaacag uccugcagca uauccaacau cgaaaccgug      660

aucgaguucc aacagaaaaa caacagacuc cucgaaauca cucgagaguu cuccguaaac      720

gccggcguca caaccccagu cucaacauac augcucacca acagcgaacu ccuaucacua      780

aucaacgaca ugccuaucac aaaugaucag aagaaacuaa ugagcaacaa cguccaaauc      840

guccgccaac aaucauacuc caucaugugc aucauaaaag aagaaguccu agccuacgug      900

guccagcuac cccucuacgg cguaauugac accccuugcu ggaaacuaca cacuucaccc      960

cucugcacaa ccaacaccaa agaagguuca aacaucugcc ucacacgaac agaccgcggc     1020

ugguacugcg acaacgccgg auccguaucc uucuuccccc aagcagaaac cugcaaaguu     1080

caauccaacc ggguauucug cgacaccaug aacucaagaa cccuucccuc cgaaguaaau     1140

cuaugcaacg ucgacauauu caacccaaaa uacgacugca aaaucaugac cuccaaaacc     1200

gaugucucca gcagcgucau caccagccuc ggcgccaucg ucuccugcua cggcaaaaca     1260

aaauguacag cauccaacaa aaaccgaggc auaaucaaaa ccuucuccaa cgggugcgau     1320

uacgucagca acaaaggcgu cgacaccguc uccgugggca acacccuaua cuacgucaac     1380

aaacaagaag gcaaaucacu guacguaaag ggcgaaccca ucaucaacuu cuaugacccu     1440

cugguguucc cauccgauga auuugacgca uccauaucuc aggucaacga aaagaucaac     1500

caaucccucg ccuucauacg caaauccgac gaacuccuac acaacgucaa cgcugguaaa     1560

agcaccacca acaucaugau caccacaauc aucaucguca uaaucguuau ccuacucucc     1620

cuuauagcag ucggacuccu ccucuacugc aaagcccgcu aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  4396
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4396
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4397
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4397
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4398
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4398
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4399
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4399
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4400
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4400
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4401
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4401
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4402
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4402
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauccucaaa      120

gcaaacgcaa uaacaacaau acuaacagca gucacuuucu gcuucgcauc cggacaaaau      180

aucacagaag aauuuuacca auccaccugc ucugcugucu ccaaaggaua ccuaucugcc      240

cucagaaccg guugguauac aucugucaua accauagaac uaucaaacau uaaagaaaac      300

aaauguaacg gaacagacgc aaaagucaaa cuuauaaaac aagaauuaga caaauacaaa      360

aacgcaguca cagaauuaca acuacuaaug caaucaaccc cagcaaccgg aucaggaucc      420

gcaauagcuu caggaguagc aguauguaaa guucuacacu uagaaggaga agucaacaaa      480

auuaaauccg cacuauuauc aaccaacaaa gcagucguau cuuuaucaaa cggaguaucu      540

guacuuacau ucaaaguacu agaccuaaaa aauuacauug auaaacaauu acuaccaaua      600

cuaaacaaac aaucauguuc caucucuaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau cacccgagaa uuuucaguaa acgcaggagu aaccacaccc      720

guaucuacau acaugcuaac aaacucugaa cuucugagcc uaauaaauga caugccaaua      780

accaacgacc aaaaaaaacu aauguccaac aacguacaaa uaguacgaca acaaucuuac      840

ucaaucaugu gcauaaucaa agaagaagua cuagcuuaug uaguccaacu uccacucuac      900

ggaguaauag acacccccug cuggaaacua cacacaucac cacuaugcac aacaaacaca      960

aaagaaggcu caaacauaug ccuaacaaga acugacagag gaugguauug ugacaaugca     1020

ggcucugucu cauucuuucc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacaa ugaacucuag aacucuccca ucagaaguca acuuaugcaa cguugacaua     1140

uucaacccaa aauaugacug uaaaauaaug acuuccaaaa cugauguauc auccuccguc     1200

auaacauccc uaggagcuau uguaucaugu uacgggaaaa ccaaaugcac agccucaaac     1260

aaaaaccgcg guaucauaaa aacauuuuca aacggaugug auuacguaag caauaaagga     1320

guagacaccg uaucaguagg aaauacacua uacuauguaa auaaacaaga aggaaaauca     1380

cuauauguca aaggagaacc aaucauaaau uucuaugacc cacuuguauu cccauccgau     1440

gaauuugacg caagcauuuc acaggucaac gaaaaaauaa accaaucacu agccuucauc     1500

agaaaaucag acgaacuacu acauaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaacaacaa ucauaauagu uaucauagua auacuacuau cucuaauagc ugucggacuc     1620

uuacuauauu gcaaagcccg auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4403
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4403
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccugaaa      120

gccaacgcca uaaccacaau ccuuaccgca gucaccuucu gcuucgccuc cggucaaaac      180

aucacagaag aguucuacca auccaccugu uccgcaguca gcaaaggcua ccucuccgca      240

cuccgaaccg gaugguacac cagcgucauc accaucgaac uauccaacau aaaggaaaau      300

aagugcaaug guacagaugc caaggucaaa cucauaaagc aagaacucga caaauacaaa      360

aacgccguca ccgaacuaca acuacuaaug caaucuaccc ccgcaacagg cucagguucc      420

gccauagccu ccggcgucgc cguuugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gcagucgucu cccucucaaa cggagucucg      540

guccucaccu ucaaaguccu cgaccucaaa aacuauauag acaaacaacu ccuacccaua      600

cucaacaaac aguccugcag cauauccaac aucgaaaccg ugaucgaguu ccaacagaaa      660

aacaacagac uccucgaaau cacucgagag uucuccguaa acgccggcgu cacaacccca      720

gucucaacau acaugcucac caacagcgaa cuccuaucac uaaucaacga caugccuauc      780

acaaaugauc agaagaaacu aaugagcaac aacguccaaa ucguccgcca acaaucauac      840

uccaucaugu gcaucauaaa agaagaaguc cuagccuacg ugguccagcu accccucuac      900

ggcguaauug acaccccuug cuggaaacua cacacuucac cccucugcac aaccaacacc      960

aaagaagguu caaacaucug ccucacacga acagaccgcg gcugguacug cgacaacgcc     1020

ggauccguau ccuucuuccc ccaagcagaa accugcaaag uucaauccaa ccggguauuc     1080

ugcgacacca ugaacucaag aacccuuccc uccgaaguaa aucuaugcaa cgucgacaua     1140

uucaacccaa aauacgacug caaaaucaug accuccaaaa ccgaugucuc cagcagcguc     1200

aucaccagcc ucggcgccau cgucuccugc uacggcaaaa caaaauguac agcauccaac     1260

aaaaaccgag gcauaaucaa aaccuucucc aacgggugcg auuacgucag caacaaaggc     1320

gucgacaccg ucuccguggg caacacccua uacuacguca acaaacaaga aggcaaauca     1380

cuguacguaa agggcgaacc caucaucaac uucuaugacc cucugguguu cccauccgau     1440

gaauuugacg cauccauauc ucaggucaac gaaaagauca accaaucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acacaacguc aacgcuggua aaagcaccac caacaucaug     1560

aucaccacaa ucaucaucgu cauaaucguu auccuacucu cccuuauagc agucggacuc     1620

cuccucuacu gcaaagcccg cuaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  4404
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4404
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4405
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4405
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4406
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4406
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4407
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4407
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4408
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4408
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4409
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4409
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4410
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4410
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauccucaaa gcaaacgcaa uaacaacaau acuaacagca      120

gucacuuucu gcuucgcauc cggacaaaau aucacagaag aauuuuacca auccaccugc      180

ucugcugucu ccaaaggaua ccuaucugcc cucagaaccg guugguauac aucugucaua      240

accauagaac uaucaaacau uaaagaaaac aaauguaacg gaacagacgc aaaagucaaa      300

cuuauaaaac aagaauuaga caaauacaaa aacgcaguca cagaauuaca acuacuaaug      360

caaucaaccc cagcaaccgg aucaggaucc gcaauagcuu caggaguagc aguauguaaa      420

guucuacacu uagaaggaga agucaacaaa auuaaauccg cacuauuauc aaccaacaaa      480

gcagucguau cuuuaucaaa cggaguaucu guacuuacau ucaaaguacu agaccuaaaa      540

aauuacauug auaaacaauu acuaccaaua cuaaacaaac aaucauguuc caucucuaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagau uacuugaaau cacccgagaa      660

uuuucaguaa acgcaggagu aaccacaccc guaucuacau acaugcuaac aaacucugaa      720

cuucugagcc uaauaaauga caugccaaua accaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa uaguacgaca acaaucuuac ucaaucaugu gcauaaucaa agaagaagua      840

cuagcuuaug uaguccaacu uccacucuac ggaguaauag acacccccug cuggaaacua      900

cacacaucac cacuaugcac aacaaacaca aaagaaggcu caaacauaug ccuaacaaga      960

acugacagag gaugguauug ugacaaugca ggcucugucu cauucuuucc acaagccgaa     1020

acaugcaaag uucaaucaaa ccgaguuuuc ugugacacaa ugaacucuag aacucuccca     1080

ucagaaguca acuuaugcaa cguugacaua uucaacccaa aauaugacug uaaaauaaug     1140

acuuccaaaa cugauguauc auccuccguc auaacauccc uaggagcuau uguaucaugu     1200

uacgggaaaa ccaaaugcac agccucaaac aaaaaccgcg guaucauaaa aacauuuuca     1260

aacggaugug auuacguaag caauaaagga guagacaccg uaucaguagg aaauacacua     1320

uacuauguaa auaaacaaga aggaaaauca cuauauguca aaggagaacc aaucauaaau     1380

uucuaugacc cacuuguauu cccauccgau gaauuugacg caagcauuuc acaggucaac     1440

gaaaaaauaa accaaucacu agccuucauc agaaaaucag acgaacuacu acauaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaacaacaa ucauaauagu uaucauagua     1560

auacuacuau cucuaauagc ugucggacuc uuacuauauu gcaaagcccg auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4411
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4411
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccugaaa gccaacgcca uaaccacaau ccuuaccgca      120

gucaccuucu gcuucgccuc cggucaaaac aucacagaag aguucuacca auccaccugu      180

uccgcaguca gcaaaggcua ccucuccgca cuccgaaccg gaugguacac cagcgucauc      240

accaucgaac uauccaacau aaaggaaaau aagugcaaug guacagaugc caaggucaaa      300

cucauaaagc aagaacucga caaauacaaa aacgccguca ccgaacuaca acuacuaaug      360

caaucuaccc ccgcaacagg cucagguucc gccauagccu ccggcgucgc cguuugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gcagucgucu cccucucaaa cggagucucg guccucaccu ucaaaguccu cgaccucaaa      540

aacuauauag acaaacaacu ccuacccaua cucaacaaac aguccugcag cauauccaac      600

aucgaaaccg ugaucgaguu ccaacagaaa aacaacagac uccucgaaau cacucgagag      660

uucuccguaa acgccggcgu cacaacccca gucucaacau acaugcucac caacagcgaa      720

cuccuaucac uaaucaacga caugccuauc acaaaugauc agaagaaacu aaugagcaac      780

aacguccaaa ucguccgcca acaaucauac uccaucaugu gcaucauaaa agaagaaguc      840

cuagccuacg ugguccagcu accccucuac ggcguaauug acaccccuug cuggaaacua      900

cacacuucac cccucugcac aaccaacacc aaagaagguu caaacaucug ccucacacga      960

acagaccgcg gcugguacug cgacaacgcc ggauccguau ccuucuuccc ccaagcagaa     1020

accugcaaag uucaauccaa ccggguauuc ugcgacacca ugaacucaag aacccuuccc     1080

uccgaaguaa aucuaugcaa cgucgacaua uucaacccaa aauacgacug caaaaucaug     1140

accuccaaaa ccgaugucuc cagcagcguc aucaccagcc ucggcgccau cgucuccugc     1200

uacggcaaaa caaaauguac agcauccaac aaaaaccgag gcauaaucaa aaccuucucc     1260

aacgggugcg auuacgucag caacaaaggc gucgacaccg ucuccguggg caacacccua     1320

uacuacguca acaaacaaga aggcaaauca cuguacguaa agggcgaacc caucaucaac     1380

uucuaugacc cucugguguu cccauccgau gaauuugacg cauccauauc ucaggucaac     1440

gaaaagauca accaaucccu cgccuucaua cgcaaauccg acgaacuccu acacaacguc     1500

aacgcuggua aaagcaccac caacaucaug aucaccacaa ucaucaucgu cauaaucguu     1560

auccuacucu cccuuauagc agucggacuc cuccucuacu gcaaagcccg cuaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  4412
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4412
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4413
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4413
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4414
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4414
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4415
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4415
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4416
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4416
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4417
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4417
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4418
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4418
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauccu caaagcaaac gcaauaacaa caauacuaac agcagucacu      180

uucugcuucg cauccggaca aaauaucaca gaagaauuuu accaauccac cugcucugcu      240

gucuccaaag gauaccuauc ugcccucaga accgguuggu auacaucugu cauaaccaua      300

gaacuaucaa acauuaaaga aaacaaaugu aacggaacag acgcaaaagu caaacuuaua      360

aaacaagaau uagacaaaua caaaaacgca gucacagaau uacaacuacu aaugcaauca      420

accccagcaa ccggaucagg auccgcaaua gcuucaggag uagcaguaug uaaaguucua      480

cacuuagaag gagaagucaa caaaauuaaa uccgcacuau uaucaaccaa caaagcaguc      540

guaucuuuau caaacggagu aucuguacuu acauucaaag uacuagaccu aaaaaauuac      600

auugauaaac aauuacuacc aauacuaaac aaacaaucau guuccaucuc uaacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agauuacuug aaaucacccg agaauuuuca      720

guaaacgcag gaguaaccac acccguaucu acauacaugc uaacaaacuc ugaacuucug      780

agccuaauaa augacaugcc aauaaccaac gaccaaaaaa aacuaauguc caacaacgua      840

caaauaguac gacaacaauc uuacucaauc augugcauaa ucaaagaaga aguacuagcu      900

uauguagucc aacuuccacu cuacggagua auagacaccc ccugcuggaa acuacacaca      960

ucaccacuau gcacaacaaa cacaaaagaa ggcucaaaca uaugccuaac aagaacugac     1020

agaggauggu auugugacaa ugcaggcucu gucucauucu uuccacaagc cgaaacaugc     1080

aaaguucaau caaaccgagu uuucugugac acaaugaacu cuagaacucu cccaucagaa     1140

gucaacuuau gcaacguuga cauauucaac ccaaaauaug acuguaaaau aaugacuucc     1200

aaaacugaug uaucauccuc cgucauaaca ucccuaggag cuauuguauc auguuacggg     1260

aaaaccaaau gcacagccuc aaacaaaaac cgcgguauca uaaaaacauu uucaaacgga     1320

ugugauuacg uaagcaauaa aggaguagac accguaucag uaggaaauac acuauacuau     1380

guaaauaaac aagaaggaaa aucacuauau gucaaaggag aaccaaucau aaauuucuau     1440

gacccacuug uauucccauc cgaugaauuu gacgcaagca uuucacaggu caacgaaaaa     1500

auaaaccaau cacuagccuu caucagaaaa ucagacgaac uacuacauaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaaca acaaucauaa uaguuaucau aguaauacua     1620

cuaucucuaa uagcugucgg acucuuacua uauugcaaag cccgauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4419
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4419
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu gaaagccaac gccauaacca caauccuuac cgcagucacc      180

uucugcuucg ccuccgguca aaacaucaca gaagaguucu accaauccac cuguuccgca      240

gucagcaaag gcuaccucuc cgcacuccga accggauggu acaccagcgu caucaccauc      300

gaacuaucca acauaaagga aaauaagugc aaugguacag augccaaggu caaacucaua      360

aagcaagaac ucgacaaaua caaaaacgcc gucaccgaac uacaacuacu aaugcaaucu      420

acccccgcaa caggcucagg uuccgccaua gccuccggcg ucgccguuug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaaa uccgcccuac ucucaaccaa caaagcaguc      540

gucucccucu caaacggagu cucgguccuc accuucaaag uccucgaccu caaaaacuau      600

auagacaaac aacuccuacc cauacucaac aaacaguccu gcagcauauc caacaucgaa      660

accgugaucg aguuccaaca gaaaaacaac agacuccucg aaaucacucg agaguucucc      720

guaaacgccg gcgucacaac cccagucuca acauacaugc ucaccaacag cgaacuccua      780

ucacuaauca acgacaugcc uaucacaaau gaucagaaga aacuaaugag caacaacguc      840

caaaucgucc gccaacaauc auacuccauc augugcauca uaaaagaaga aguccuagcc      900

uacguggucc agcuaccccu cuacggcgua auugacaccc cuugcuggaa acuacacacu      960

ucaccccucu gcacaaccaa caccaaagaa gguucaaaca ucugccucac acgaacagac     1020

cgcggcuggu acugcgacaa cgccggaucc guauccuucu ucccccaagc agaaaccugc     1080

aaaguucaau ccaaccgggu auucugcgac accaugaacu caagaacccu ucccuccgaa     1140

guaaaucuau gcaacgucga cauauucaac ccaaaauacg acugcaaaau caugaccucc     1200

aaaaccgaug ucuccagcag cgucaucacc agccucggcg ccaucgucuc cugcuacggc     1260

aaaacaaaau guacagcauc caacaaaaac cgaggcauaa ucaaaaccuu cuccaacggg     1320

ugcgauuacg ucagcaacaa aggcgucgac accgucuccg ugggcaacac ccuauacuac     1380

gucaacaaac aagaaggcaa aucacuguac guaaagggcg aacccaucau caacuucuau     1440

gacccucugg uguucccauc cgaugaauuu gacgcaucca uaucucaggu caacgaaaag     1500

aucaaccaau cccucgccuu cauacgcaaa uccgacgaac uccuacacaa cgucaacgcu     1560

gguaaaagca ccaccaacau caugaucacc acaaucauca ucgucauaau cguuauccua     1620

cucucccuua uagcagucgg acuccuccuc uacugcaaag cccgcuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  4420
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4420
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4421
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4421
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4422
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4422
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4423
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4423
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4424
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4424
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4425
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4425
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4426
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4426
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauccucaa agcaaacgca      120

auaacaacaa uacuaacagc agucacuuuc ugcuucgcau ccggacaaaa uaucacagaa      180

gaauuuuacc aauccaccug cucugcuguc uccaaaggau accuaucugc ccucagaacc      240

gguugguaua caucugucau aaccauagaa cuaucaaaca uuaaagaaaa caaauguaac      300

ggaacagacg caaaagucaa acuuauaaaa caagaauuag acaaauacaa aaacgcaguc      360

acagaauuac aacuacuaau gcaaucaacc ccagcaaccg gaucaggauc cgcaauagcu      420

ucaggaguag caguauguaa aguucuacac uuagaaggag aagucaacaa aauuaaaucc      480

gcacuauuau caaccaacaa agcagucgua ucuuuaucaa acggaguauc uguacuuaca      540

uucaaaguac uagaccuaaa aaauuacauu gauaaacaau uacuaccaau acuaaacaaa      600

caaucauguu ccaucucuaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa ucacccgaga auuuucagua aacgcaggag uaaccacacc cguaucuaca      720

uacaugcuaa caaacucuga acuucugagc cuaauaaaug acaugccaau aaccaacgac      780

caaaaaaaac uaauguccaa caacguacaa auaguacgac aacaaucuua cucaaucaug      840

ugcauaauca aagaagaagu acuagcuuau guaguccaac uuccacucua cggaguaaua      900

gacacccccu gcuggaaacu acacacauca ccacuaugca caacaaacac aaaagaaggc      960

ucaaacauau gccuaacaag aacugacaga ggaugguauu gugacaaugc aggcucuguc     1020

ucauucuuuc cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacaca     1080

augaacucua gaacucuccc aucagaaguc aacuuaugca acguugacau auucaaccca     1140

aaauaugacu guaaaauaau gacuuccaaa acugauguau cauccuccgu cauaacaucc     1200

cuaggagcua uuguaucaug uuacgggaaa accaaaugca cagccucaaa caaaaaccgc     1260

gguaucauaa aaacauuuuc aaacggaugu gauuacguaa gcaauaaagg aguagacacc     1320

guaucaguag gaaauacacu auacuaugua aauaaacaag aaggaaaauc acuauauguc     1380

aaaggagaac caaucauaaa uuucuaugac ccacuuguau ucccauccga ugaauuugac     1440

gcaagcauuu cacaggucaa cgaaaaaaua aaccaaucac uagccuucau cagaaaauca     1500

gacgaacuac uacauaacgu aaacgccgga aaaucaacaa ccaacauaau gauaacaaca     1560

aucauaauag uuaucauagu aauacuacua ucucuaauag cugucggacu cuuacuauau     1620

ugcaaagccc gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4427
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4427
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccugaa agccaacgcc      120

auaaccacaa uccuuaccgc agucaccuuc ugcuucgccu ccggucaaaa caucacagaa      180

gaguucuacc aauccaccug uuccgcaguc agcaaaggcu accucuccgc acuccgaacc      240

ggaugguaca ccagcgucau caccaucgaa cuauccaaca uaaaggaaaa uaagugcaau      300

gguacagaug ccaaggucaa acucauaaag caagaacucg acaaauacaa aaacgccguc      360

accgaacuac aacuacuaau gcaaucuacc cccgcaacag gcucagguuc cgccauagcc      420

uccggcgucg ccguuugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agcagucguc ucccucucaa acggagucuc gguccucacc      540

uucaaagucc ucgaccucaa aaacuauaua gacaaacaac uccuacccau acucaacaaa      600

caguccugca gcauauccaa caucgaaacc gugaucgagu uccaacagaa aaacaacaga      660

cuccucgaaa ucacucgaga guucuccgua aacgccggcg ucacaacccc agucucaaca      720

uacaugcuca ccaacagcga acuccuauca cuaaucaacg acaugccuau cacaaaugau      780

cagaagaaac uaaugagcaa caacguccaa aucguccgcc aacaaucaua cuccaucaug      840

ugcaucauaa aagaagaagu ccuagccuac gugguccagc uaccccucua cggcguaauu      900

gacaccccuu gcuggaaacu acacacuuca ccccucugca caaccaacac caaagaaggu      960

ucaaacaucu gccucacacg aacagaccgc ggcugguacu gcgacaacgc cggauccgua     1020

uccuucuucc cccaagcaga aaccugcaaa guucaaucca accggguauu cugcgacacc     1080

augaacucaa gaacccuucc cuccgaagua aaucuaugca acgucgacau auucaaccca     1140

aaauacgacu gcaaaaucau gaccuccaaa accgaugucu ccagcagcgu caucaccagc     1200

cucggcgcca ucgucuccug cuacggcaaa acaaaaugua cagcauccaa caaaaaccga     1260

ggcauaauca aaaccuucuc caacgggugc gauuacguca gcaacaaagg cgucgacacc     1320

gucuccgugg gcaacacccu auacuacguc aacaaacaag aaggcaaauc acuguacgua     1380

aagggcgaac ccaucaucaa cuucuaugac ccucuggugu ucccauccga ugaauuugac     1440

gcauccauau cucaggucaa cgaaaagauc aaccaauccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu caacgcuggu aaaagcacca ccaacaucau gaucaccaca     1560

aucaucaucg ucauaaucgu uauccuacuc ucccuuauag cagucggacu ccuccucuac     1620

ugcaaagccc gcuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  4428
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4428
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4429
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4429
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4430
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4430
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4431
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4431
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4432
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4432
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4433
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4433
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4434
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4434
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauccucaa agcaaacgca      120

auaacaacaa uacuaacagc agucacuuuc ugcuucgcau ccggacaaaa uaucacagaa      180

gaauuuuacc aauccaccug cucugcuguc uccaaaggau accuaucugc ccucagaacc      240

gguugguaua caucugucau aaccauagaa cuaucaaaca uuaaagaaaa caaauguaac      300

ggaacagacg caaaagucaa acuuauaaaa caagaauuag acaaauacaa aaacgcaguc      360

acagaauuac aacuacuaau gcaaucaacc ccagcaaccg gaucaggauc cgcaauagcu      420

ucaggaguag caguauguaa aguucuacac uuagaaggag aagucaacaa aauuaaaucc      480

gcacuauuau caaccaacaa agcagucgua ucuuuaucaa acggaguauc uguacuuaca      540

uucaaaguac uagaccuaaa aaauuacauu gauaaacaau uacuaccaau acuaaacaaa      600

caaucauguu ccaucucuaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa ucacccgaga auuuucagua aacgcaggag uaaccacacc cguaucuaca      720

uacaugcuaa caaacucuga acuucugagc cuaauaaaug acaugccaau aaccaacgac      780

caaaaaaaac uaauguccaa caacguacaa auaguacgac aacaaucuua cucaaucaug      840

ugcauaauca aagaagaagu acuagcuuau guaguccaac uuccacucua cggaguaaua      900

gacacccccu gcuggaaacu acacacauca ccacuaugca caacaaacac aaaagaaggc      960

ucaaacauau gccuaacaag aacugacaga ggaugguauu gugacaaugc aggcucuguc     1020

ucauucuuuc cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacaca     1080

augaacucua gaacucuccc aucagaaguc aacuuaugca acguugacau auucaaccca     1140

aaauaugacu guaaaauaau gacuuccaaa acugauguau cauccuccgu cauaacaucc     1200

cuaggagcua uuguaucaug uuacgggaaa accaaaugca cagccucaaa caaaaaccgc     1260

gguaucauaa aaacauuuuc aaacggaugu gauuacguaa gcaauaaagg aguagacacc     1320

guaucaguag gaaauacacu auacuaugua aauaaacaag aaggaaaauc acuauauguc     1380

aaaggagaac caaucauaaa uuucuaugac ccacuuguau ucccauccga ugaauuugac     1440

gcaagcauuu cacaggucaa cgaaaaaaua aaccaaucac uagccuucau cagaaaauca     1500

gacgaacuac uacauaacgu aaacgccgga aaaucaacaa ccaacauaau gauaacaaca     1560

aucauaauag uuaucauagu aauacuacua ucucuaauag cugucggacu cuuacuauau     1620

ugcaaagccc gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4435
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4435
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccugaa agccaacgcc      120

auaaccacaa uccuuaccgc agucaccuuc ugcuucgccu ccggucaaaa caucacagaa      180

gaguucuacc aauccaccug uuccgcaguc agcaaaggcu accucuccgc acuccgaacc      240

ggaugguaca ccagcgucau caccaucgaa cuauccaaca uaaaggaaaa uaagugcaau      300

gguacagaug ccaaggucaa acucauaaag caagaacucg acaaauacaa aaacgccguc      360

accgaacuac aacuacuaau gcaaucuacc cccgcaacag gcucagguuc cgccauagcc      420

uccggcgucg ccguuugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agcagucguc ucccucucaa acggagucuc gguccucacc      540

uucaaagucc ucgaccucaa aaacuauaua gacaaacaac uccuacccau acucaacaaa      600

caguccugca gcauauccaa caucgaaacc gugaucgagu uccaacagaa aaacaacaga      660

cuccucgaaa ucacucgaga guucuccgua aacgccggcg ucacaacccc agucucaaca      720

uacaugcuca ccaacagcga acuccuauca cuaaucaacg acaugccuau cacaaaugau      780

cagaagaaac uaaugagcaa caacguccaa aucguccgcc aacaaucaua cuccaucaug      840

ugcaucauaa aagaagaagu ccuagccuac gugguccagc uaccccucua cggcguaauu      900

gacaccccuu gcuggaaacu acacacuuca ccccucugca caaccaacac caaagaaggu      960

ucaaacaucu gccucacacg aacagaccgc ggcugguacu gcgacaacgc cggauccgua     1020

uccuucuucc cccaagcaga aaccugcaaa guucaaucca accggguauu cugcgacacc     1080

augaacucaa gaacccuucc cuccgaagua aaucuaugca acgucgacau auucaaccca     1140

aaauacgacu gcaaaaucau gaccuccaaa accgaugucu ccagcagcgu caucaccagc     1200

cucggcgcca ucgucuccug cuacggcaaa acaaaaugua cagcauccaa caaaaaccga     1260

ggcauaauca aaaccuucuc caacgggugc gauuacguca gcaacaaagg cgucgacacc     1320

gucuccgugg gcaacacccu auacuacguc aacaaacaag aaggcaaauc acuguacgua     1380

aagggcgaac ccaucaucaa cuucuaugac ccucuggugu ucccauccga ugaauuugac     1440

gcauccauau cucaggucaa cgaaaagauc aaccaauccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu caacgcuggu aaaagcacca ccaacaucau gaucaccaca     1560

aucaucaucg ucauaaucgu uauccuacuc ucccuuauag cagucggacu ccuccucuac     1620

ugcaaagccc gcuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  4436
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4436
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4437
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4437
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4438
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4438
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4439
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4439
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4440
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4440
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4441
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4441
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4442
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4442
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauccucaa agcaaacgca      120

auaacaacaa uacuaacagc agucacuuuc ugcuucgcau ccggacaaaa uaucacagaa      180

gaauuuuacc aauccaccug cucugcuguc uccaaaggau accuaucugc ccucagaacc      240

gguugguaua caucugucau aaccauagaa cuaucaaaca uuaaagaaaa caaauguaac      300

ggaacagacg caaaagucaa acuuauaaaa caagaauuag acaaauacaa aaacgcaguc      360

acagaauuac aacuacuaau gcaaucaacc ccagcaaccg gaucaggauc cgcaauagcu      420

ucaggaguag caguauguaa aguucuacac uuagaaggag aagucaacaa aauuaaaucc      480

gcacuauuau caaccaacaa agcagucgua ucuuuaucaa acggaguauc uguacuuaca      540

uucaaaguac uagaccuaaa aaauuacauu gauaaacaau uacuaccaau acuaaacaaa      600

caaucauguu ccaucucuaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa ucacccgaga auuuucagua aacgcaggag uaaccacacc cguaucuaca      720

uacaugcuaa caaacucuga acuucugagc cuaauaaaug acaugccaau aaccaacgac      780

caaaaaaaac uaauguccaa caacguacaa auaguacgac aacaaucuua cucaaucaug      840

ugcauaauca aagaagaagu acuagcuuau guaguccaac uuccacucua cggaguaaua      900

gacacccccu gcuggaaacu acacacauca ccacuaugca caacaaacac aaaagaaggc      960

ucaaacauau gccuaacaag aacugacaga ggaugguauu gugacaaugc aggcucuguc     1020

ucauucuuuc cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacaca     1080

augaacucua gaacucuccc aucagaaguc aacuuaugca acguugacau auucaaccca     1140

aaauaugacu guaaaauaau gacuuccaaa acugauguau cauccuccgu cauaacaucc     1200

cuaggagcua uuguaucaug uuacgggaaa accaaaugca cagccucaaa caaaaaccgc     1260

gguaucauaa aaacauuuuc aaacggaugu gauuacguaa gcaauaaagg aguagacacc     1320

guaucaguag gaaauacacu auacuaugua aauaaacaag aaggaaaauc acuauauguc     1380

aaaggagaac caaucauaaa uuucuaugac ccacuuguau ucccauccga ugaauuugac     1440

gcaagcauuu cacaggucaa cgaaaaaaua aaccaaucac uagccuucau cagaaaauca     1500

gacgaacuac uacauaacgu aaacgccgga aaaucaacaa ccaacauaau gauaacaaca     1560

aucauaauag uuaucauagu aauacuacua ucucuaauag cugucggacu cuuacuauau     1620

ugcaaagccc gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4443
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4443
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccugaa agccaacgcc      120

auaaccacaa uccuuaccgc agucaccuuc ugcuucgccu ccggucaaaa caucacagaa      180

gaguucuacc aauccaccug uuccgcaguc agcaaaggcu accucuccgc acuccgaacc      240

ggaugguaca ccagcgucau caccaucgaa cuauccaaca uaaaggaaaa uaagugcaau      300

gguacagaug ccaaggucaa acucauaaag caagaacucg acaaauacaa aaacgccguc      360

accgaacuac aacuacuaau gcaaucuacc cccgcaacag gcucagguuc cgccauagcc      420

uccggcgucg ccguuugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agcagucguc ucccucucaa acggagucuc gguccucacc      540

uucaaagucc ucgaccucaa aaacuauaua gacaaacaac uccuacccau acucaacaaa      600

caguccugca gcauauccaa caucgaaacc gugaucgagu uccaacagaa aaacaacaga      660

cuccucgaaa ucacucgaga guucuccgua aacgccggcg ucacaacccc agucucaaca      720

uacaugcuca ccaacagcga acuccuauca cuaaucaacg acaugccuau cacaaaugau      780

cagaagaaac uaaugagcaa caacguccaa aucguccgcc aacaaucaua cuccaucaug      840

ugcaucauaa aagaagaagu ccuagccuac gugguccagc uaccccucua cggcguaauu      900

gacaccccuu gcuggaaacu acacacuuca ccccucugca caaccaacac caaagaaggu      960

ucaaacaucu gccucacacg aacagaccgc ggcugguacu gcgacaacgc cggauccgua     1020

uccuucuucc cccaagcaga aaccugcaaa guucaaucca accggguauu cugcgacacc     1080

augaacucaa gaacccuucc cuccgaagua aaucuaugca acgucgacau auucaaccca     1140

aaauacgacu gcaaaaucau gaccuccaaa accgaugucu ccagcagcgu caucaccagc     1200

cucggcgcca ucgucuccug cuacggcaaa acaaaaugua cagcauccaa caaaaaccga     1260

ggcauaauca aaaccuucuc caacgggugc gauuacguca gcaacaaagg cgucgacacc     1320

gucuccgugg gcaacacccu auacuacguc aacaaacaag aaggcaaauc acuguacgua     1380

aagggcgaac ccaucaucaa cuucuaugac ccucuggugu ucccauccga ugaauuugac     1440

gcauccauau cucaggucaa cgaaaagauc aaccaauccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu caacgcuggu aaaagcacca ccaacaucau gaucaccaca     1560

aucaucaucg ucauaaucgu uauccuacuc ucccuuauag cagucggacu ccuccucuac     1620

ugcaaagccc gcuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  4444
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4444
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4445
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4445
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacuacguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4446
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4446
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4447
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4447
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugca guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

uguauuauaa aggaggaagu guuagcauau guagugcaac ugccccucua cggagucauc      900

gacacuccuu gcuggaaacu ucauacaagc ccacugugua ccacuaauac aaaggagggc      960

ucgaacauuu gcuugacccg aacggaucgu ggcugguacu gugacaaugc cgggucugug     1020

uccuucuuuc cccaggcuga aaccugcaag guucagucaa acagaguguu cugugauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu gcaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcca ucguguccug uuacgguaag acuaaaugca cagcaagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugu gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuauguu aacaagcaag aggguaaaag ccuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccuuugguau ucccauccga ugaguuugac     1440

gcuucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgccuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgcggga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac     1620

ugcaaagcac gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4448
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4448
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4449
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4449
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugca gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

uguaucauua aggaggaagu ccuggcuuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu gcuggaaacu gcauacgucu ccucucugua ccacaaauac caaggagggg      960

uccaacaucu gccugacacg gaccgaucgc ggaugguacu gugacaaugc cggcagcguc     1020

ucuuucuuuc cccaggcgga aacgugcaag gugcagagca acagaguuuu cugugauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu gcaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcca ucgugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugu gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuauguu aacaagcaag agggcaaauc ucuguacgug     1380

aagggggaac ccaucauuaa cuuuuaugac ccucucgucu uccccagcga ugaguuugac     1440

gccuccaucu cucaggugaa ugagaaaauu aaccagagcc uggcuuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgccgga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguac     1620

ugcaaagcua gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4450
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4450
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauccucaa agcaaacgca      120

auaacaacaa uacuaacagc agucacuuuc ugcuucgcau ccggacaaaa uaucacagaa      180

gaauuuuacc aauccaccug cucugcuguc uccaaaggau accuaucugc ccucagaacc      240

gguugguaua caucugucau aaccauagaa cuaucaaaca uuaaagaaaa caaauguaac      300

ggaacagacg caaaagucaa acuuauaaaa caagaauuag acaaauacaa aaacgcaguc      360

acagaauuac aacuacuaau gcaaucaacc ccagcaaccg gaucaggauc cgcaauagcu      420

ucaggaguag caguauguaa aguucuacac uuagaaggag aagucaacaa aauuaaaucc      480

gcacuauuau caaccaacaa agcagucgua ucuuuaucaa acggaguauc uguacuuaca      540

uucaaaguac uagaccuaaa aaauuacauu gauaaacaau uacuaccaau acuaaacaaa      600

caaucauguu ccaucucuaa cauagaaaca guaauagaau uucaacaaaa aaauaacaga      660

uuacuugaaa ucacccgaga auuuucagua aacgcaggag uaaccacacc cguaucuaca      720

uacaugcuaa caaacucuga acuucugagc cuaauaaaug acaugccaau aaccaacgac      780

caaaaaaaac uaauguccaa caacguacaa auaguacgac aacaaucuua cucaaucaug      840

ugcauaauca aagaagaagu acuagcuuau guaguccaac uuccacucua cggaguaaua      900

gacacccccu gcuggaaacu acacacauca ccacuaugca caacaaacac aaaagaaggc      960

ucaaacauau gccuaacaag aacugacaga ggaugguauu gugacaaugc aggcucuguc     1020

ucauucuuuc cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacaca     1080

augaacucua gaacucuccc aucagaaguc aacuuaugca acguugacau auucaaccca     1140

aaauaugacu guaaaauaau gacuuccaaa acugauguau cauccuccgu cauaacaucc     1200

cuaggagcua uuguaucaug uuacgggaaa accaaaugca cagccucaaa caaaaaccgc     1260

gguaucauaa aaacauuuuc aaacggaugu gauuacguaa gcaauaaagg aguagacacc     1320

guaucaguag gaaauacacu auacuaugua aauaaacaag aaggaaaauc acuauauguc     1380

aaaggagaac caaucauaaa uuucuaugac ccacuuguau ucccauccga ugaauuugac     1440

gcaagcauuu cacaggucaa cgaaaaaaua aaccaaucac uagccuucau cagaaaauca     1500

gacgaacuac uacauaacgu aaacgccgga aaaucaacaa ccaacauaau gauaacaaca     1560

aucauaauag uuaucauagu aauacuacua ucucuaauag cugucggacu cuuacuauau     1620

ugcaaagccc gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4451
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4451
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac uaauccugaa agccaacgcc      120

auaaccacaa uccuuaccgc agucaccuuc ugcuucgccu ccggucaaaa caucacagaa      180

gaguucuacc aauccaccug uuccgcaguc agcaaaggcu accucuccgc acuccgaacc      240

ggaugguaca ccagcgucau caccaucgaa cuauccaaca uaaaggaaaa uaagugcaau      300

gguacagaug ccaaggucaa acucauaaag caagaacucg acaaauacaa aaacgccguc      360

accgaacuac aacuacuaau gcaaucuacc cccgcaacag gcucagguuc cgccauagcc      420

uccggcgucg ccguuugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agcagucguc ucccucucaa acggagucuc gguccucacc      540

uucaaagucc ucgaccucaa aaacuauaua gacaaacaac uccuacccau acucaacaaa      600

caguccugca gcauauccaa caucgaaacc gugaucgagu uccaacagaa aaacaacaga      660

cuccucgaaa ucacucgaga guucuccgua aacgccggcg ucacaacccc agucucaaca      720

uacaugcuca ccaacagcga acuccuauca cuaaucaacg acaugccuau cacaaaugau      780

cagaagaaac uaaugagcaa caacguccaa aucguccgcc aacaaucaua cuccaucaug      840

ugcaucauaa aagaagaagu ccuagccuac gugguccagc uaccccucua cggcguaauu      900

gacaccccuu gcuggaaacu acacacuuca ccccucugca caaccaacac caaagaaggu      960

ucaaacaucu gccucacacg aacagaccgc ggcugguacu gcgacaacgc cggauccgua     1020

uccuucuucc cccaagcaga aaccugcaaa guucaaucca accggguauu cugcgacacc     1080

augaacucaa gaacccuucc cuccgaagua aaucuaugca acgucgacau auucaaccca     1140

aaauacgacu gcaaaaucau gaccuccaaa accgaugucu ccagcagcgu caucaccagc     1200

cucggcgcca ucgucuccug cuacggcaaa acaaaaugua cagcauccaa caaaaaccga     1260

ggcauaauca aaaccuucuc caacgggugc gauuacguca gcaacaaagg cgucgacacc     1320

gucuccgugg gcaacacccu auacuacguc aacaaacaag aaggcaaauc acuguacgua     1380

aagggcgaac ccaucaucaa cuucuaugac ccucuggugu ucccauccga ugaauuugac     1440

gcauccauau cucaggucaa cgaaaagauc aaccaauccc ucgccuucau acgcaaaucc     1500

gacgaacucc uacacaacgu caacgcuggu aaaagcacca ccaacaucau gaucaccaca     1560

aucaucaucg ucauaaucgu uauccuacuc ucccuuauag cagucggacu ccuccucuac     1620

ugcaaagccc gcuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4452
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4452
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4453
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4453
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4454
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4454
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4455
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4455
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4456
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4456
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4457
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4457
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4458
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4458
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uccucaaagc aaacgcaaua acaacaauac      120

uaacagcagu cacuuucugc uucgcauccg gacaaaauau cacagaagaa uuuuaccaau      180

ccaccugcuc ugcugucucc aaaggauacc uaucugcccu cagaaccggu ugguauacau      240

cugucauaac cauagaacua ucaaacauua aagaaaacaa auguaacgga acagacgcaa      300

aagucaaacu uauaaaacaa gaauuagaca aauacaaaaa cgcagucaca gaauuacaac      360

uacuaaugca aucaacccca gcaaccggau caggauccgc aauagcuuca ggaguagcag      420

uauguaaagu ucuacacuua gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa      480

ccaacaaagc agucguaucu uuaucaaacg gaguaucugu acuuacauuc aaaguacuag      540

accuaaaaaa uuacauugau aaacaauuac uaccaauacu aaacaaacaa ucauguucca      600

ucucuaacau agaaacagua auagaauuuc aacaaaaaaa uaacagauua cuugaaauca      660

cccgagaauu uucaguaaac gcaggaguaa ccacacccgu aucuacauac augcuaacaa      720

acucugaacu ucugagccua auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaaua guacgacaac aaucuuacuc aaucaugugc auaaucaaag      840

aagaaguacu agcuuaugua guccaacuuc cacucuacgg aguaauagac acccccugcu      900

ggaaacuaca cacaucacca cuaugcacaa caaacacaaa agaaggcuca aacauaugcc      960

uaacaagaac ugacagagga ugguauugug acaaugcagg cucugucuca uucuuuccac     1020

aagccgaaac augcaaaguu caaucaaacc gaguuuucug ugacacaaug aacucuagaa     1080

cucucccauc agaagucaac uuaugcaacg uugacauauu caacccaaaa uaugacugua     1140

aaauaaugac uuccaaaacu gauguaucau ccuccgucau aacaucccua ggagcuauug     1200

uaucauguua cgggaaaacc aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa     1260

cauuuucaaa cggaugugau uacguaagca auaaaggagu agacaccgua ucaguaggaa     1320

auacacuaua cuauguaaau aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa     1380

ucauaaauuu cuaugaccca cuuguauucc cauccgauga auuugacgca agcauuucac     1440

aggucaacga aaaaauaaac caaucacuag ccuucaucag aaaaucagac gaacuacuac     1500

auaacguaaa cgccggaaaa ucaacaacca acauaaugau aacaacaauc auaauaguua     1560

ucauaguaau acuacuaucu cuaauagcug ucggacucuu acuauauugc aaagcccgau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4459
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4459
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccugaaagc caacgccaua accacaaucc      120

uuaccgcagu caccuucugc uucgccuccg gucaaaacau cacagaagag uucuaccaau      180

ccaccuguuc cgcagucagc aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca      240

gcgucaucac caucgaacua uccaacauaa aggaaaauaa gugcaauggu acagaugcca      300

aggucaaacu cauaaagcaa gaacucgaca aauacaaaaa cgccgucacc gaacuacaac      360

uacuaaugca aucuaccccc gcaacaggcu cagguuccgc cauagccucc ggcgucgccg      420

uuugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc agucgucucc cucucaaacg gagucucggu ccucaccuuc aaaguccucg      540

accucaaaaa cuauauagac aaacaacucc uacccauacu caacaaacag uccugcagca      600

uauccaacau cgaaaccgug aucgaguucc aacagaaaaa caacagacuc cucgaaauca      660

cucgagaguu cuccguaaac gccggcguca caaccccagu cucaacauac augcucacca      720

acagcgaacu ccuaucacua aucaacgaca ugccuaucac aaaugaucag aagaaacuaa      780

ugagcaacaa cguccaaauc guccgccaac aaucauacuc caucaugugc aucauaaaag      840

aagaaguccu agccuacgug guccagcuac cccucuacgg cguaauugac accccuugcu      900

ggaaacuaca cacuucaccc cucugcacaa ccaacaccaa agaagguuca aacaucugcc      960

ucacacgaac agaccgcggc ugguacugcg acaacgccgg auccguaucc uucuuccccc     1020

aagcagaaac cugcaaaguu caauccaacc ggguauucug cgacaccaug aacucaagaa     1080

cccuucccuc cgaaguaaau cuaugcaacg ucgacauauu caacccaaaa uacgacugca     1140

aaaucaugac cuccaaaacc gaugucucca gcagcgucau caccagccuc ggcgccaucg     1200

ucuccugcua cggcaaaaca aaauguacag cauccaacaa aaaccgaggc auaaucaaaa     1260

ccuucuccaa cgggugcgau uacgucagca acaaaggcgu cgacaccguc uccgugggca     1320

acacccuaua cuacgucaac aaacaagaag gcaaaucacu guacguaaag ggcgaaccca     1380

ucaucaacuu cuaugacccu cugguguucc cauccgauga auuugacgca uccauaucuc     1440

aggucaacga aaagaucaac caaucccucg ccuucauacg caaauccgac gaacuccuac     1500

acaacgucaa cgcugguaaa agcaccacca acaucaugau caccacaauc aucaucguca     1560

uaaucguuau ccuacucucc cuuauagcag ucggacuccu ccucuacugc aaagcccgcu     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  4460
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4460
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4461
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4461
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cuacgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg cguucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4462
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4462
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4463
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4463
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucaugcagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugu auuauaaagg      840

aggaaguguu agcauaugua gugcaacugc cccucuacgg agucaucgac acuccuugcu      900

ggaaacuuca uacaagccca cuguguacca cuaauacaaa ggagggcucg aacauuugcu      960

ugacccgaac ggaucguggc ugguacugug acaaugccgg gucugugucc uucuuucccc     1020

aggcugaaac cugcaagguu cagucaaaca gaguguucug ugauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugca     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagccaucg     1200

uguccuguua cgguaagacu aaaugcacag caagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugugau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuauguuaac aagcaagagg guaaaagccu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu uugguauucc cauccgauga guuugacgcu ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg ccuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgcgggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgccg ucggccugcu uuuguacugc aaagcacgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4464
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4464
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4465
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4465
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccugcagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugu aucauuaagg      840

aggaaguccu ggcuuaugug guucaacucc cucuguacgg cgugaucgac acacccugcu      900

ggaaacugca uacgucuccu cucuguacca caaauaccaa ggaggggucc aacaucugcc      960

ugacacggac cgaucgcgga ugguacugug acaaugccgg cagcgucucu uucuuucccc     1020

aggcggaaac gugcaaggug cagagcaaca gaguuuucug ugauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugca     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggccaucg     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugugau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuauguuaac aagcaagagg gcaaaucucu guacgugaag ggggaaccca     1380

ucauuaacuu uuaugacccu cucgucuucc ccagcgauga guuugacgcc uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg cuuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgccggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguacugc aaagcuagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4466
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4466
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uccucaaagc aaacgcaaua acaacaauac      120

uaacagcagu cacuuucugc uucgcauccg gacaaaauau cacagaagaa uuuuaccaau      180

ccaccugcuc ugcugucucc aaaggauacc uaucugcccu cagaaccggu ugguauacau      240

cugucauaac cauagaacua ucaaacauua aagaaaacaa auguaacgga acagacgcaa      300

aagucaaacu uauaaaacaa gaauuagaca aauacaaaaa cgcagucaca gaauuacaac      360

uacuaaugca aucaacccca gcaaccggau caggauccgc aauagcuuca ggaguagcag      420

uauguaaagu ucuacacuua gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa      480

ccaacaaagc agucguaucu uuaucaaacg gaguaucugu acuuacauuc aaaguacuag      540

accuaaaaaa uuacauugau aaacaauuac uaccaauacu aaacaaacaa ucauguucca      600

ucucuaacau agaaacagua auagaauuuc aacaaaaaaa uaacagauua cuugaaauca      660

cccgagaauu uucaguaaac gcaggaguaa ccacacccgu aucuacauac augcuaacaa      720

acucugaacu ucugagccua auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa      780

uguccaacaa cguacaaaua guacgacaac aaucuuacuc aaucaugugc auaaucaaag      840

aagaaguacu agcuuaugua guccaacuuc cacucuacgg aguaauagac acccccugcu      900

ggaaacuaca cacaucacca cuaugcacaa caaacacaaa agaaggcuca aacauaugcc      960

uaacaagaac ugacagagga ugguauugug acaaugcagg cucugucuca uucuuuccac     1020

aagccgaaac augcaaaguu caaucaaacc gaguuuucug ugacacaaug aacucuagaa     1080

cucucccauc agaagucaac uuaugcaacg uugacauauu caacccaaaa uaugacugua     1140

aaauaaugac uuccaaaacu gauguaucau ccuccgucau aacaucccua ggagcuauug     1200

uaucauguua cgggaaaacc aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa     1260

cauuuucaaa cggaugugau uacguaagca auaaaggagu agacaccgua ucaguaggaa     1320

auacacuaua cuauguaaau aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa     1380

ucauaaauuu cuaugaccca cuuguauucc cauccgauga auuugacgca agcauuucac     1440

aggucaacga aaaaauaaac caaucacuag ccuucaucag aaaaucagac gaacuacuac     1500

auaacguaaa cgccggaaaa ucaacaacca acauaaugau aacaacaauc auaauaguua     1560

ucauaguaau acuacuaucu cuaauagcug ucggacucuu acuauauugc aaagcccgau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4467
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4467
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuaa uccugaaagc caacgccaua accacaaucc      120

uuaccgcagu caccuucugc uucgccuccg gucaaaacau cacagaagag uucuaccaau      180

ccaccuguuc cgcagucagc aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca      240

gcgucaucac caucgaacua uccaacauaa aggaaaauaa gugcaauggu acagaugcca      300

aggucaaacu cauaaagcaa gaacucgaca aauacaaaaa cgccgucacc gaacuacaac      360

uacuaaugca aucuaccccc gcaacaggcu cagguuccgc cauagccucc ggcgucgccg      420

uuugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc agucgucucc cucucaaacg gagucucggu ccucaccuuc aaaguccucg      540

accucaaaaa cuauauagac aaacaacucc uacccauacu caacaaacag uccugcagca      600

uauccaacau cgaaaccgug aucgaguucc aacagaaaaa caacagacuc cucgaaauca      660

cucgagaguu cuccguaaac gccggcguca caaccccagu cucaacauac augcucacca      720

acagcgaacu ccuaucacua aucaacgaca ugccuaucac aaaugaucag aagaaacuaa      780

ugagcaacaa cguccaaauc guccgccaac aaucauacuc caucaugugc aucauaaaag      840

aagaaguccu agccuacgug guccagcuac cccucuacgg cguaauugac accccuugcu      900

ggaaacuaca cacuucaccc cucugcacaa ccaacaccaa agaagguuca aacaucugcc      960

ucacacgaac agaccgcggc ugguacugcg acaacgccgg auccguaucc uucuuccccc     1020

aagcagaaac cugcaaaguu caauccaacc ggguauucug cgacaccaug aacucaagaa     1080

cccuucccuc cgaaguaaau cuaugcaacg ucgacauauu caacccaaaa uacgacugca     1140

aaaucaugac cuccaaaacc gaugucucca gcagcgucau caccagccuc ggcgccaucg     1200

ucuccugcua cggcaaaaca aaauguacag cauccaacaa aaaccgaggc auaaucaaaa     1260

ccuucuccaa cgggugcgau uacgucagca acaaaggcgu cgacaccguc uccgugggca     1320

acacccuaua cuacgucaac aaacaagaag gcaaaucacu guacguaaag ggcgaaccca     1380

ucaucaacuu cuaugacccu cugguguucc cauccgauga auuugacgca uccauaucuc     1440

aggucaacga aaagaucaac caaucccucg ccuucauacg caaauccgac gaacuccuac     1500

acaacgucaa cgcugguaaa agcaccacca acaucaugau caccacaauc aucaucguca     1560

uaaucguuau ccuacucucc cuuauagcag ucggacuccu ccucuacugc aaagcccgcu     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  4468
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4468
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4469
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4469
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4470
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4470
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4471
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4471
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4472
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4472
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4473
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4473
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4474
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4474
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauccucaaa gcaaacgcaa uaacaacaau acuaacagca      120

gucacuuucu gcuucgcauc cggacaaaau aucacagaag aauuuuacca auccaccugc      180

ucugcugucu ccaaaggaua ccuaucugcc cucagaaccg guugguauac aucugucaua      240

accauagaac uaucaaacau uaaagaaaac aaauguaacg gaacagacgc aaaagucaaa      300

cuuauaaaac aagaauuaga caaauacaaa aacgcaguca cagaauuaca acuacuaaug      360

caaucaaccc cagcaaccgg aucaggaucc gcaauagcuu caggaguagc aguauguaaa      420

guucuacacu uagaaggaga agucaacaaa auuaaauccg cacuauuauc aaccaacaaa      480

gcagucguau cuuuaucaaa cggaguaucu guacuuacau ucaaaguacu agaccuaaaa      540

aauuacauug auaaacaauu acuaccaaua cuaaacaaac aaucauguuc caucucuaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagau uacuugaaau cacccgagaa      660

uuuucaguaa acgcaggagu aaccacaccc guaucuacau acaugcuaac aaacucugaa      720

cuucugagcc uaauaaauga caugccaaua accaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa uaguacgaca acaaucuuac ucaaucaugu gcauaaucaa agaagaagua      840

cuagcuuaug uaguccaacu uccacucuac ggaguaauag acacccccug cuggaaacua      900

cacacaucac cacuaugcac aacaaacaca aaagaaggcu caaacauaug ccuaacaaga      960

acugacagag gaugguauug ugacaaugca ggcucugucu cauucuuucc acaagccgaa     1020

acaugcaaag uucaaucaaa ccgaguuuuc ugugacacaa ugaacucuag aacucuccca     1080

ucagaaguca acuuaugcaa cguugacaua uucaacccaa aauaugacug uaaaauaaug     1140

acuuccaaaa cugauguauc auccuccguc auaacauccc uaggagcuau uguaucaugu     1200

uacgggaaaa ccaaaugcac agccucaaac aaaaaccgcg guaucauaaa aacauuuuca     1260

aacggaugug auuacguaag caauaaagga guagacaccg uaucaguagg aaauacacua     1320

uacuauguaa auaaacaaga aggaaaauca cuauauguca aaggagaacc aaucauaaau     1380

uucuaugacc cacuuguauu cccauccgau gaauuugacg caagcauuuc acaggucaac     1440

gaaaaaauaa accaaucacu agccuucauc agaaaaucag acgaacuacu acauaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaacaacaa ucauaauagu uaucauagua     1560

auacuacuau cucuaauagc ugucggacuc uuacuauauu gcaaagcccg auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4475
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4475
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccugaaa gccaacgcca uaaccacaau ccuuaccgca      120

gucaccuucu gcuucgccuc cggucaaaac aucacagaag aguucuacca auccaccugu      180

uccgcaguca gcaaaggcua ccucuccgca cuccgaaccg gaugguacac cagcgucauc      240

accaucgaac uauccaacau aaaggaaaau aagugcaaug guacagaugc caaggucaaa      300

cucauaaagc aagaacucga caaauacaaa aacgccguca ccgaacuaca acuacuaaug      360

caaucuaccc ccgcaacagg cucagguucc gccauagccu ccggcgucgc cguuugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gcagucgucu cccucucaaa cggagucucg guccucaccu ucaaaguccu cgaccucaaa      540

aacuauauag acaaacaacu ccuacccaua cucaacaaac aguccugcag cauauccaac      600

aucgaaaccg ugaucgaguu ccaacagaaa aacaacagac uccucgaaau cacucgagag      660

uucuccguaa acgccggcgu cacaacccca gucucaacau acaugcucac caacagcgaa      720

cuccuaucac uaaucaacga caugccuauc acaaaugauc agaagaaacu aaugagcaac      780

aacguccaaa ucguccgcca acaaucauac uccaucaugu gcaucauaaa agaagaaguc      840

cuagccuacg ugguccagcu accccucuac ggcguaauug acaccccuug cuggaaacua      900

cacacuucac cccucugcac aaccaacacc aaagaagguu caaacaucug ccucacacga      960

acagaccgcg gcugguacug cgacaacgcc ggauccguau ccuucuuccc ccaagcagaa     1020

accugcaaag uucaauccaa ccggguauuc ugcgacacca ugaacucaag aacccuuccc     1080

uccgaaguaa aucuaugcaa cgucgacaua uucaacccaa aauacgacug caaaaucaug     1140

accuccaaaa ccgaugucuc cagcagcguc aucaccagcc ucggcgccau cgucuccugc     1200

uacggcaaaa caaaauguac agcauccaac aaaaaccgag gcauaaucaa aaccuucucc     1260

aacgggugcg auuacgucag caacaaaggc gucgacaccg ucuccguggg caacacccua     1320

uacuacguca acaaacaaga aggcaaauca cuguacguaa agggcgaacc caucaucaac     1380

uucuaugacc cucugguguu cccauccgau gaauuugacg cauccauauc ucaggucaac     1440

gaaaagauca accaaucccu cgccuucaua cgcaaauccg acgaacuccu acacaacguc     1500

aacgcuggua aaagcaccac caacaucaug aucaccacaa ucaucaucgu cauaaucguu     1560

auccuacucu cccuuauagc agucggacuc cuccucuacu gcaaagcccg cuaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  4476
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4476
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4477
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4477
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacuacguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgcguucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4478
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4478
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4479
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4479
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucaugcag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu guauuauaaa ggaggaagug      840

uuagcauaug uagugcaacu gccccucuac ggagucaucg acacuccuug cuggaaacuu      900

cauacaagcc cacuguguac cacuaauaca aaggagggcu cgaacauuug cuugacccga      960

acggaucgug gcugguacug ugacaaugcc gggucugugu ccuucuuucc ccaggcugaa     1020

accugcaagg uucagucaaa cagaguguuc ugugauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug caagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagccau cguguccugu     1200

uacgguaaga cuaaaugcac agcaagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugug auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuauguua acaagcaaga ggguaaaagc cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cuuugguauu cccauccgau gaguuugacg cuucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgccuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgcgggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc cgucggccug cuuuuguacu gcaaagcacg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4480
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4480
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4481
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4481
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccugcag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu guaucauuaa ggaggaaguc      840

cuggcuuaug ugguucaacu cccucuguac ggcgugaucg acacacccug cuggaaacug      900

cauacgucuc cucucuguac cacaaauacc aaggaggggu ccaacaucug ccugacacgg      960

accgaucgcg gaugguacug ugacaaugcc ggcagcgucu cuuucuuucc ccaggcggaa     1020

acgugcaagg ugcagagcaa cagaguuuuc ugugauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug caagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggccau cgugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugug auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuauguua acaagcaaga gggcaaaucu cuguacguga agggggaacc caucauuaac     1380

uuuuaugacc cucucgucuu ccccagcgau gaguuugacg ccuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggcuuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgccggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguacu gcaaagcuag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4482
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4482
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauccucaaa gcaaacgcaa uaacaacaau acuaacagca      120

gucacuuucu gcuucgcauc cggacaaaau aucacagaag aauuuuacca auccaccugc      180

ucugcugucu ccaaaggaua ccuaucugcc cucagaaccg guugguauac aucugucaua      240

accauagaac uaucaaacau uaaagaaaac aaauguaacg gaacagacgc aaaagucaaa      300

cuuauaaaac aagaauuaga caaauacaaa aacgcaguca cagaauuaca acuacuaaug      360

caaucaaccc cagcaaccgg aucaggaucc gcaauagcuu caggaguagc aguauguaaa      420

guucuacacu uagaaggaga agucaacaaa auuaaauccg cacuauuauc aaccaacaaa      480

gcagucguau cuuuaucaaa cggaguaucu guacuuacau ucaaaguacu agaccuaaaa      540

aauuacauug auaaacaauu acuaccaaua cuaaacaaac aaucauguuc caucucuaac      600

auagaaacag uaauagaauu ucaacaaaaa aauaacagau uacuugaaau cacccgagaa      660

uuuucaguaa acgcaggagu aaccacaccc guaucuacau acaugcuaac aaacucugaa      720

cuucugagcc uaauaaauga caugccaaua accaacgacc aaaaaaaacu aauguccaac      780

aacguacaaa uaguacgaca acaaucuuac ucaaucaugu gcauaaucaa agaagaagua      840

cuagcuuaug uaguccaacu uccacucuac ggaguaauag acacccccug cuggaaacua      900

cacacaucac cacuaugcac aacaaacaca aaagaaggcu caaacauaug ccuaacaaga      960

acugacagag gaugguauug ugacaaugca ggcucugucu cauucuuucc acaagccgaa     1020

acaugcaaag uucaaucaaa ccgaguuuuc ugugacacaa ugaacucuag aacucuccca     1080

ucagaaguca acuuaugcaa cguugacaua uucaacccaa aauaugacug uaaaauaaug     1140

acuuccaaaa cugauguauc auccuccguc auaacauccc uaggagcuau uguaucaugu     1200

uacgggaaaa ccaaaugcac agccucaaac aaaaaccgcg guaucauaaa aacauuuuca     1260

aacggaugug auuacguaag caauaaagga guagacaccg uaucaguagg aaauacacua     1320

uacuauguaa auaaacaaga aggaaaauca cuauauguca aaggagaacc aaucauaaau     1380

uucuaugacc cacuuguauu cccauccgau gaauuugacg caagcauuuc acaggucaac     1440

gaaaaaauaa accaaucacu agccuucauc agaaaaucag acgaacuacu acauaacgua     1500

aacgccggaa aaucaacaac caacauaaug auaacaacaa ucauaauagu uaucauagua     1560

auacuacuau cucuaauagc ugucggacuc uuacuauauu gcaaagcccg auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4483
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4483
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu aauccugaaa gccaacgcca uaaccacaau ccuuaccgca      120

gucaccuucu gcuucgccuc cggucaaaac aucacagaag aguucuacca auccaccugu      180

uccgcaguca gcaaaggcua ccucuccgca cuccgaaccg gaugguacac cagcgucauc      240

accaucgaac uauccaacau aaaggaaaau aagugcaaug guacagaugc caaggucaaa      300

cucauaaagc aagaacucga caaauacaaa aacgccguca ccgaacuaca acuacuaaug      360

caaucuaccc ccgcaacagg cucagguucc gccauagccu ccggcgucgc cguuugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gcagucgucu cccucucaaa cggagucucg guccucaccu ucaaaguccu cgaccucaaa      540

aacuauauag acaaacaacu ccuacccaua cucaacaaac aguccugcag cauauccaac      600

aucgaaaccg ugaucgaguu ccaacagaaa aacaacagac uccucgaaau cacucgagag      660

uucuccguaa acgccggcgu cacaacccca gucucaacau acaugcucac caacagcgaa      720

cuccuaucac uaaucaacga caugccuauc acaaaugauc agaagaaacu aaugagcaac      780

aacguccaaa ucguccgcca acaaucauac uccaucaugu gcaucauaaa agaagaaguc      840

cuagccuacg ugguccagcu accccucuac ggcguaauug acaccccuug cuggaaacua      900

cacacuucac cccucugcac aaccaacacc aaagaagguu caaacaucug ccucacacga      960

acagaccgcg gcugguacug cgacaacgcc ggauccguau ccuucuuccc ccaagcagaa     1020

accugcaaag uucaauccaa ccggguauuc ugcgacacca ugaacucaag aacccuuccc     1080

uccgaaguaa aucuaugcaa cgucgacaua uucaacccaa aauacgacug caaaaucaug     1140

accuccaaaa ccgaugucuc cagcagcguc aucaccagcc ucggcgccau cgucuccugc     1200

uacggcaaaa caaaauguac agcauccaac aaaaaccgag gcauaaucaa aaccuucucc     1260

aacgggugcg auuacgucag caacaaaggc gucgacaccg ucuccguggg caacacccua     1320

uacuacguca acaaacaaga aggcaaauca cuguacguaa agggcgaacc caucaucaac     1380

uucuaugacc cucugguguu cccauccgau gaauuugacg cauccauauc ucaggucaac     1440

gaaaagauca accaaucccu cgccuucaua cgcaaauccg acgaacuccu acacaacguc     1500

aacgcuggua aaagcaccac caacaucaug aucaccacaa ucaucaucgu cauaaucguu     1560

auccuacucu cccuuauagc agucggacuc cuccucuacu gcaaagcccg cuaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4484
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4484
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4485
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4485
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4486
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4486
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4487
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4487
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4488
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4488
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4489
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4489
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4490
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4490
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau ccucaaagca      120

aacgcaauaa caacaauacu aacagcaguc acuuucugcu ucgcauccgg acaaaauauc      180

acagaagaau uuuaccaauc caccugcucu gcugucucca aaggauaccu aucugcccuc      240

agaaccgguu gguauacauc ugucauaacc auagaacuau caaacauuaa agaaaacaaa      300

uguaacggaa cagacgcaaa agucaaacuu auaaaacaag aauuagacaa auacaaaaac      360

gcagucacag aauuacaacu acuaaugcaa ucaaccccag caaccggauc aggauccgca      420

auagcuucag gaguagcagu auguaaaguu cuacacuuag aaggagaagu caacaaaauu      480

aaauccgcac uauuaucaac caacaaagca gucguaucuu uaucaaacgg aguaucugua      540

cuuacauuca aaguacuaga ccuaaaaaau uacauugaua aacaauuacu accaauacua      600

aacaaacaau cauguuccau cucuaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaaucac ccgagaauuu ucaguaaacg caggaguaac cacacccgua      720

ucuacauaca ugcuaacaaa cucugaacuu cugagccuaa uaaaugacau gccaauaacc      780

aacgaccaaa aaaaacuaau guccaacaac guacaaauag uacgacaaca aucuuacuca      840

aucaugugca uaaucaaaga agaaguacua gcuuauguag uccaacuucc acucuacgga      900

guaauagaca cccccugcug gaaacuacac acaucaccac uaugcacaac aaacacaaaa      960

gaaggcucaa acauaugccu aacaagaacu gacagaggau gguauuguga caaugcaggc     1020

ucugucucau ucuuuccaca agccgaaaca ugcaaaguuc aaucaaaccg aguuuucugu     1080

gacacaauga acucuagaac ucucccauca gaagucaacu uaugcaacgu ugacauauuc     1140

aacccaaaau augacuguaa aauaaugacu uccaaaacug auguaucauc cuccgucaua     1200

acaucccuag gagcuauugu aucauguuac gggaaaacca aaugcacagc cucaaacaaa     1260

aaccgcggua ucauaaaaac auuuucaaac ggaugugauu acguaagcaa uaaaggagua     1320

gacaccguau caguaggaaa uacacuauac uauguaaaua aacaagaagg aaaaucacua     1380

uaugucaaag gagaaccaau cauaaauuuc uaugacccac uuguauuccc auccgaugaa     1440

uuugacgcaa gcauuucaca ggucaacgaa aaaauaaacc aaucacuagc cuucaucaga     1500

aaaucagacg aacuacuaca uaacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

acaacaauca uaauaguuau cauaguaaua cuacuaucuc uaauagcugu cggacucuua     1620

cuauauugca aagcccgaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4491
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4491
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccugaaagcc      120

aacgccauaa ccacaauccu uaccgcaguc accuucugcu ucgccuccgg ucaaaacauc      180

acagaagagu ucuaccaauc caccuguucc gcagucagca aaggcuaccu cuccgcacuc      240

cgaaccggau gguacaccag cgucaucacc aucgaacuau ccaacauaaa ggaaaauaag      300

ugcaauggua cagaugccaa ggucaaacuc auaaagcaag aacucgacaa auacaaaaac      360

gccgucaccg aacuacaacu acuaaugcaa ucuacccccg caacaggcuc agguuccgcc      420

auagccuccg gcgucgccgu uugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aaauccgccc uacucucaac caacaaagca gucgucuccc ucucaaacgg agucucgguc      540

cucaccuuca aaguccucga ccucaaaaac uauauagaca aacaacuccu acccauacuc      600

aacaaacagu ccugcagcau auccaacauc gaaaccguga ucgaguucca acagaaaaac      660

aacagacucc ucgaaaucac ucgagaguuc uccguaaacg ccggcgucac aaccccaguc      720

ucaacauaca ugcucaccaa cagcgaacuc cuaucacuaa ucaacgacau gccuaucaca      780

aaugaucaga agaaacuaau gagcaacaac guccaaaucg uccgccaaca aucauacucc      840

aucaugugca ucauaaaaga agaaguccua gccuacgugg uccagcuacc ccucuacggc      900

guaauugaca ccccuugcug gaaacuacac acuucacccc ucugcacaac caacaccaaa      960

gaagguucaa acaucugccu cacacgaaca gaccgcggcu gguacugcga caacgccgga     1020

uccguauccu ucuuccccca agcagaaacc ugcaaaguuc aauccaaccg gguauucugc     1080

gacaccauga acucaagaac ccuucccucc gaaguaaauc uaugcaacgu cgacauauuc     1140

aacccaaaau acgacugcaa aaucaugacc uccaaaaccg augucuccag cagcgucauc     1200

accagccucg gcgccaucgu cuccugcuac ggcaaaacaa aauguacagc auccaacaaa     1260

aaccgaggca uaaucaaaac cuucuccaac gggugcgauu acgucagcaa caaaggcguc     1320

gacaccgucu ccgugggcaa cacccuauac uacgucaaca aacaagaagg caaaucacug     1380

uacguaaagg gcgaacccau caucaacuuc uaugacccuc ugguguuccc auccgaugaa     1440

uuugacgcau ccauaucuca ggucaacgaa aagaucaacc aaucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca caacgucaac gcugguaaaa gcaccaccaa caucaugauc     1560

accacaauca ucaucgucau aaucguuauc cuacucuccc uuauagcagu cggacuccuc     1620

cucuacugca aagcccgcua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  4492
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4492
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4493
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4493
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac uacgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc guucauccgc     1500

aagagcgacg agcugcugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4494
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4494
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4495
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4495
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu caugcaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugua uuauaaagga ggaaguguua gcauauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuugcug gaaacuucau acaagcccac uguguaccac uaauacaaag      960

gagggcucga acauuugcuu gacccgaacg gaucguggcu gguacuguga caaugccggg     1020

ucuguguccu ucuuucccca ggcugaaacc ugcaagguuc agucaaacag aguguucugu     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauugcaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagccaucgu guccuguuac gguaagacua aaugcacagc aagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugugauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uauguuaaca agcaagaggg uaaaagccug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuu ugguauuccc auccgaugag     1440

uuugacgcuu cuauaucgca ggucaaugag aaaaucaacc agagccucgc cuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gcgggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgccgu cggccugcuu     1620

uuguacugca aagcacgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4496
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4496
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4497
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4497
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccugcagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugua ucauuaagga ggaaguccug gcuuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccugcug gaaacugcau acgucuccuc ucuguaccac aaauaccaag      960

gaggggucca acaucugccu gacacggacc gaucgcggau gguacuguga caaugccggc     1020

agcgucucuu ucuuucccca ggcggaaacg ugcaaggugc agagcaacag aguuuucugu     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauugcaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggccaucgu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugugauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uauguuaaca agcaagaggg caaaucucug     1380

uacgugaagg gggaacccau cauuaacuuu uaugacccuc ucgucuuccc cagcgaugag     1440

uuugacgccu ccaucucuca ggugaaugag aaaauuaacc agagccuggc uuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gccggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguacugca aagcuagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4498
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4498
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau ccucaaagca      120

aacgcaauaa caacaauacu aacagcaguc acuuucugcu ucgcauccgg acaaaauauc      180

acagaagaau uuuaccaauc caccugcucu gcugucucca aaggauaccu aucugcccuc      240

agaaccgguu gguauacauc ugucauaacc auagaacuau caaacauuaa agaaaacaaa      300

uguaacggaa cagacgcaaa agucaaacuu auaaaacaag aauuagacaa auacaaaaac      360

gcagucacag aauuacaacu acuaaugcaa ucaaccccag caaccggauc aggauccgca      420

auagcuucag gaguagcagu auguaaaguu cuacacuuag aaggagaagu caacaaaauu      480

aaauccgcac uauuaucaac caacaaagca gucguaucuu uaucaaacgg aguaucugua      540

cuuacauuca aaguacuaga ccuaaaaaau uacauugaua aacaauuacu accaauacua      600

aacaaacaau cauguuccau cucuaacaua gaaacaguaa uagaauuuca acaaaaaaau      660

aacagauuac uugaaaucac ccgagaauuu ucaguaaacg caggaguaac cacacccgua      720

ucuacauaca ugcuaacaaa cucugaacuu cugagccuaa uaaaugacau gccaauaacc      780

aacgaccaaa aaaaacuaau guccaacaac guacaaauag uacgacaaca aucuuacuca      840

aucaugugca uaaucaaaga agaaguacua gcuuauguag uccaacuucc acucuacgga      900

guaauagaca cccccugcug gaaacuacac acaucaccac uaugcacaac aaacacaaaa      960

gaaggcucaa acauaugccu aacaagaacu gacagaggau gguauuguga caaugcaggc     1020

ucugucucau ucuuuccaca agccgaaaca ugcaaaguuc aaucaaaccg aguuuucugu     1080

gacacaauga acucuagaac ucucccauca gaagucaacu uaugcaacgu ugacauauuc     1140

aacccaaaau augacuguaa aauaaugacu uccaaaacug auguaucauc cuccgucaua     1200

acaucccuag gagcuauugu aucauguuac gggaaaacca aaugcacagc cucaaacaaa     1260

aaccgcggua ucauaaaaac auuuucaaac ggaugugauu acguaagcaa uaaaggagua     1320

gacaccguau caguaggaaa uacacuauac uauguaaaua aacaagaagg aaaaucacua     1380

uaugucaaag gagaaccaau cauaaauuuc uaugacccac uuguauuccc auccgaugaa     1440

uuugacgcaa gcauuucaca ggucaacgaa aaaauaaacc aaucacuagc cuucaucaga     1500

aaaucagacg aacuacuaca uaacguaaac gccggaaaau caacaaccaa cauaaugaua     1560

acaacaauca uaauaguuau cauaguaaua cuacuaucuc uaauagcugu cggacucuua     1620

cuauauugca aagcccgaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4499
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4499
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacuaau ccugaaagcc      120

aacgccauaa ccacaauccu uaccgcaguc accuucugcu ucgccuccgg ucaaaacauc      180

acagaagagu ucuaccaauc caccuguucc gcagucagca aaggcuaccu cuccgcacuc      240

cgaaccggau gguacaccag cgucaucacc aucgaacuau ccaacauaaa ggaaaauaag      300

ugcaauggua cagaugccaa ggucaaacuc auaaagcaag aacucgacaa auacaaaaac      360

gccgucaccg aacuacaacu acuaaugcaa ucuacccccg caacaggcuc agguuccgcc      420

auagccuccg gcgucgccgu uugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aaauccgccc uacucucaac caacaaagca gucgucuccc ucucaaacgg agucucgguc      540

cucaccuuca aaguccucga ccucaaaaac uauauagaca aacaacuccu acccauacuc      600

aacaaacagu ccugcagcau auccaacauc gaaaccguga ucgaguucca acagaaaaac      660

aacagacucc ucgaaaucac ucgagaguuc uccguaaacg ccggcgucac aaccccaguc      720

ucaacauaca ugcucaccaa cagcgaacuc cuaucacuaa ucaacgacau gccuaucaca      780

aaugaucaga agaaacuaau gagcaacaac guccaaaucg uccgccaaca aucauacucc      840

aucaugugca ucauaaaaga agaaguccua gccuacgugg uccagcuacc ccucuacggc      900

guaauugaca ccccuugcug gaaacuacac acuucacccc ucugcacaac caacaccaaa      960

gaagguucaa acaucugccu cacacgaaca gaccgcggcu gguacugcga caacgccgga     1020

uccguauccu ucuuccccca agcagaaacc ugcaaaguuc aauccaaccg gguauucugc     1080

gacaccauga acucaagaac ccuucccucc gaaguaaauc uaugcaacgu cgacauauuc     1140

aacccaaaau acgacugcaa aaucaugacc uccaaaaccg augucuccag cagcgucauc     1200

accagccucg gcgccaucgu cuccugcuac ggcaaaacaa aauguacagc auccaacaaa     1260

aaccgaggca uaaucaaaac cuucuccaac gggugcgauu acgucagcaa caaaggcguc     1320

gacaccgucu ccgugggcaa cacccuauac uacgucaaca aacaagaagg caaaucacug     1380

uacguaaagg gcgaacccau caucaacuuc uaugacccuc ugguguuccc auccgaugaa     1440

uuugacgcau ccauaucuca ggucaacgaa aagaucaacc aaucccucgc cuucauacgc     1500

aaauccgacg aacuccuaca caacgucaac gcugguaaaa gcaccaccaa caucaugauc     1560

accacaauca ucaucgucau aaucguuauc cuacucuccc uuauagcagu cggacuccuc     1620

cucuacugca aagcccgcua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  4500
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4500
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4501
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4501
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4502
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4502
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4503
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4503
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca      960

agcccacugu guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau     1020

cguggcuggu acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc     1080

aagguucagu caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu     1260

aagacuaaau gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau     1380

guuaacaagc aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4504
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4504
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4505
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4505
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg      960

ucuccucucu guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau     1020

cgcggauggu acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc     1080

aaggugcaga gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau     1380

guuaacaagc aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau     1440

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uacugcaaag cuagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4506
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4506
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauccu caaagcaaac gcaauaacaa caauacuaac agcagucacu      180

uucugcuucg cauccggaca aaauaucaca gaagaauuuu accaauccac cugcucugcu      240

gucuccaaag gauaccuauc ugcccucaga accgguuggu auacaucugu cauaaccaua      300

gaacuaucaa acauuaaaga aaacaaaugu aacggaacag acgcaaaagu caaacuuaua      360

aaacaagaau uagacaaaua caaaaacgca gucacagaau uacaacuacu aaugcaauca      420

accccagcaa ccggaucagg auccgcaaua gcuucaggag uagcaguaug uaaaguucua      480

cacuuagaag gagaagucaa caaaauuaaa uccgcacuau uaucaaccaa caaagcaguc      540

guaucuuuau caaacggagu aucuguacuu acauucaaag uacuagaccu aaaaaauuac      600

auugauaaac aauuacuacc aauacuaaac aaacaaucau guuccaucuc uaacauagaa      660

acaguaauag aauuucaaca aaaaaauaac agauuacuug aaaucacccg agaauuuuca      720

guaaacgcag gaguaaccac acccguaucu acauacaugc uaacaaacuc ugaacuucug      780

agccuaauaa augacaugcc aauaaccaac gaccaaaaaa aacuaauguc caacaacgua      840

caaauaguac gacaacaauc uuacucaauc augugcauaa ucaaagaaga aguacuagcu      900

uauguagucc aacuuccacu cuacggagua auagacaccc ccugcuggaa acuacacaca      960

ucaccacuau gcacaacaaa cacaaaagaa ggcucaaaca uaugccuaac aagaacugac     1020

agaggauggu auugugacaa ugcaggcucu gucucauucu uuccacaagc cgaaacaugc     1080

aaaguucaau caaaccgagu uuucugugac acaaugaacu cuagaacucu cccaucagaa     1140

gucaacuuau gcaacguuga cauauucaac ccaaaauaug acuguaaaau aaugacuucc     1200

aaaacugaug uaucauccuc cgucauaaca ucccuaggag cuauuguauc auguuacggg     1260

aaaaccaaau gcacagccuc aaacaaaaac cgcgguauca uaaaaacauu uucaaacgga     1320

ugugauuacg uaagcaauaa aggaguagac accguaucag uaggaaauac acuauacuau     1380

guaaauaaac aagaaggaaa aucacuauau gucaaaggag aaccaaucau aaauuucuau     1440

gacccacuug uauucccauc cgaugaauuu gacgcaagca uuucacaggu caacgaaaaa     1500

auaaaccaau cacuagccuu caucagaaaa ucagacgaac uacuacauaa cguaaacgcc     1560

ggaaaaucaa caaccaacau aaugauaaca acaaucauaa uaguuaucau aguaauacua     1620

cuaucucuaa uagcugucgg acucuuacua uauugcaaag cccgauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4507
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4507
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacuaauccu gaaagccaac gccauaacca caauccuuac cgcagucacc      180

uucugcuucg ccuccgguca aaacaucaca gaagaguucu accaauccac cuguuccgca      240

gucagcaaag gcuaccucuc cgcacuccga accggauggu acaccagcgu caucaccauc      300

gaacuaucca acauaaagga aaauaagugc aaugguacag augccaaggu caaacucaua      360

aagcaagaac ucgacaaaua caaaaacgcc gucaccgaac uacaacuacu aaugcaaucu      420

acccccgcaa caggcucagg uuccgccaua gccuccggcg ucgccguuug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaaa uccgcccuac ucucaaccaa caaagcaguc      540

gucucccucu caaacggagu cucgguccuc accuucaaag uccucgaccu caaaaacuau      600

auagacaaac aacuccuacc cauacucaac aaacaguccu gcagcauauc caacaucgaa      660

accgugaucg aguuccaaca gaaaaacaac agacuccucg aaaucacucg agaguucucc      720

guaaacgccg gcgucacaac cccagucuca acauacaugc ucaccaacag cgaacuccua      780

ucacuaauca acgacaugcc uaucacaaau gaucagaaga aacuaaugag caacaacguc      840

caaaucgucc gccaacaauc auacuccauc augugcauca uaaaagaaga aguccuagcc      900

uacguggucc agcuaccccu cuacggcgua auugacaccc cuugcuggaa acuacacacu      960

ucaccccucu gcacaaccaa caccaaagaa gguucaaaca ucugccucac acgaacagac     1020

cgcggcuggu acugcgacaa cgccggaucc guauccuucu ucccccaagc agaaaccugc     1080

aaaguucaau ccaaccgggu auucugcgac accaugaacu caagaacccu ucccuccgaa     1140

guaaaucuau gcaacgucga cauauucaac ccaaaauacg acugcaaaau caugaccucc     1200

aaaaccgaug ucuccagcag cgucaucacc agccucggcg ccaucgucuc cugcuacggc     1260

aaaacaaaau guacagcauc caacaaaaac cgaggcauaa ucaaaaccuu cuccaacggg     1320

ugcgauuacg ucagcaacaa aggcgucgac accgucuccg ugggcaacac ccuauacuac     1380

gucaacaaac aagaaggcaa aucacuguac guaaagggcg aacccaucau caacuucuau     1440

gacccucugg uguucccauc cgaugaauuu gacgcaucca uaucucaggu caacgaaaag     1500

aucaaccaau cccucgccuu cauacgcaaa uccgacgaac uccuacacaa cgucaacgcu     1560

gguaaaagca ccaccaacau caugaucacc acaaucauca ucgucauaau cguuauccua     1620

cucucccuua uagcagucgg acuccuccuc uacugcaaag cccgcuaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4508
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4508
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4509
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4509
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4510
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4510
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4511
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4511
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4512
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4512
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4513
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4513
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4514
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4514
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauccucaaa      120

gcaaacgcaa uaacaacaau acuaacagca gucacuuucu gcuucgcauc cggacaaaau      180

aucacagaag aauuuuacca auccaccugc ucugcugucu ccaaaggaua ccuaucugcc      240

cucagaaccg guugguauac aucugucaua accauagaac uaucaaacau uaaagaaaac      300

aaauguaacg gaacagacgc aaaagucaaa cuuauaaaac aagaauuaga caaauacaaa      360

aacgcaguca cagaauuaca acuacuaaug caaucaaccc cagcaaccgg aucaggaucc      420

gcaauagcuu caggaguagc aguauguaaa guucuacacu uagaaggaga agucaacaaa      480

auuaaauccg cacuauuauc aaccaacaaa gcagucguau cuuuaucaaa cggaguaucu      540

guacuuacau ucaaaguacu agaccuaaaa aauuacauug auaaacaauu acuaccaaua      600

cuaaacaaac aaucauguuc caucucuaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau cacccgagaa uuuucaguaa acgcaggagu aaccacaccc      720

guaucuacau acaugcuaac aaacucugaa cuucugagcc uaauaaauga caugccaaua      780

accaacgacc aaaaaaaacu aauguccaac aacguacaaa uaguacgaca acaaucuuac      840

ucaaucaugu gcauaaucaa agaagaagua cuagcuuaug uaguccaacu uccacucuac      900

ggaguaauag acacccccug cuggaaacua cacacaucac cacuaugcac aacaaacaca      960

aaagaaggcu caaacauaug ccuaacaaga acugacagag gaugguauug ugacaaugca     1020

ggcucugucu cauucuuucc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacaa ugaacucuag aacucuccca ucagaaguca acuuaugcaa cguugacaua     1140

uucaacccaa aauaugacug uaaaauaaug acuuccaaaa cugauguauc auccuccguc     1200

auaacauccc uaggagcuau uguaucaugu uacgggaaaa ccaaaugcac agccucaaac     1260

aaaaaccgcg guaucauaaa aacauuuuca aacggaugug auuacguaag caauaaagga     1320

guagacaccg uaucaguagg aaauacacua uacuauguaa auaaacaaga aggaaaauca     1380

cuauauguca aaggagaacc aaucauaaau uucuaugacc cacuuguauu cccauccgau     1440

gaauuugacg caagcauuuc acaggucaac gaaaaaauaa accaaucacu agccuucauc     1500

agaaaaucag acgaacuacu acauaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaacaacaa ucauaauagu uaucauagua auacuacuau cucuaauagc ugucggacuc     1620

uuacuauauu gcaaagcccg auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4515
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4515
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccugaaa      120

gccaacgcca uaaccacaau ccuuaccgca gucaccuucu gcuucgccuc cggucaaaac      180

aucacagaag aguucuacca auccaccugu uccgcaguca gcaaaggcua ccucuccgca      240

cuccgaaccg gaugguacac cagcgucauc accaucgaac uauccaacau aaaggaaaau      300

aagugcaaug guacagaugc caaggucaaa cucauaaagc aagaacucga caaauacaaa      360

aacgccguca ccgaacuaca acuacuaaug caaucuaccc ccgcaacagg cucagguucc      420

gccauagccu ccggcgucgc cguuugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gcagucgucu cccucucaaa cggagucucg      540

guccucaccu ucaaaguccu cgaccucaaa aacuauauag acaaacaacu ccuacccaua      600

cucaacaaac aguccugcag cauauccaac aucgaaaccg ugaucgaguu ccaacagaaa      660

aacaacagac uccucgaaau cacucgagag uucuccguaa acgccggcgu cacaacccca      720

gucucaacau acaugcucac caacagcgaa cuccuaucac uaaucaacga caugccuauc      780

acaaaugauc agaagaaacu aaugagcaac aacguccaaa ucguccgcca acaaucauac      840

uccaucaugu gcaucauaaa agaagaaguc cuagccuacg ugguccagcu accccucuac      900

ggcguaauug acaccccuug cuggaaacua cacacuucac cccucugcac aaccaacacc      960

aaagaagguu caaacaucug ccucacacga acagaccgcg gcugguacug cgacaacgcc     1020

ggauccguau ccuucuuccc ccaagcagaa accugcaaag uucaauccaa ccggguauuc     1080

ugcgacacca ugaacucaag aacccuuccc uccgaaguaa aucuaugcaa cgucgacaua     1140

uucaacccaa aauacgacug caaaaucaug accuccaaaa ccgaugucuc cagcagcguc     1200

aucaccagcc ucggcgccau cgucuccugc uacggcaaaa caaaauguac agcauccaac     1260

aaaaaccgag gcauaaucaa aaccuucucc aacgggugcg auuacgucag caacaaaggc     1320

gucgacaccg ucuccguggg caacacccua uacuacguca acaaacaaga aggcaaauca     1380

cuguacguaa agggcgaacc caucaucaac uucuaugacc cucugguguu cccauccgau     1440

gaauuugacg cauccauauc ucaggucaac gaaaagauca accaaucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acacaacguc aacgcuggua aaagcaccac caacaucaug     1560

aucaccacaa ucaucaucgu cauaaucguu auccuacucu cccuuauagc agucggacuc     1620

cuccucuacu gcaaagcccg cuaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  4516
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4516
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4517
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4517
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4518
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4518
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4519
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4519
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4520
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4520
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4521
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4521
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4522
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4522
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauccucaaa      120

gcaaacgcaa uaacaacaau acuaacagca gucacuuucu gcuucgcauc cggacaaaau      180

aucacagaag aauuuuacca auccaccugc ucugcugucu ccaaaggaua ccuaucugcc      240

cucagaaccg guugguauac aucugucaua accauagaac uaucaaacau uaaagaaaac      300

aaauguaacg gaacagacgc aaaagucaaa cuuauaaaac aagaauuaga caaauacaaa      360

aacgcaguca cagaauuaca acuacuaaug caaucaaccc cagcaaccgg aucaggaucc      420

gcaauagcuu caggaguagc aguauguaaa guucuacacu uagaaggaga agucaacaaa      480

auuaaauccg cacuauuauc aaccaacaaa gcagucguau cuuuaucaaa cggaguaucu      540

guacuuacau ucaaaguacu agaccuaaaa aauuacauug auaaacaauu acuaccaaua      600

cuaaacaaac aaucauguuc caucucuaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau cacccgagaa uuuucaguaa acgcaggagu aaccacaccc      720

guaucuacau acaugcuaac aaacucugaa cuucugagcc uaauaaauga caugccaaua      780

accaacgacc aaaaaaaacu aauguccaac aacguacaaa uaguacgaca acaaucuuac      840

ucaaucaugu gcauaaucaa agaagaagua cuagcuuaug uaguccaacu uccacucuac      900

ggaguaauag acacccccug cuggaaacua cacacaucac cacuaugcac aacaaacaca      960

aaagaaggcu caaacauaug ccuaacaaga acugacagag gaugguauug ugacaaugca     1020

ggcucugucu cauucuuucc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacaa ugaacucuag aacucuccca ucagaaguca acuuaugcaa cguugacaua     1140

uucaacccaa aauaugacug uaaaauaaug acuuccaaaa cugauguauc auccuccguc     1200

auaacauccc uaggagcuau uguaucaugu uacgggaaaa ccaaaugcac agccucaaac     1260

aaaaaccgcg guaucauaaa aacauuuuca aacggaugug auuacguaag caauaaagga     1320

guagacaccg uaucaguagg aaauacacua uacuauguaa auaaacaaga aggaaaauca     1380

cuauauguca aaggagaacc aaucauaaau uucuaugacc cacuuguauu cccauccgau     1440

gaauuugacg caagcauuuc acaggucaac gaaaaaauaa accaaucacu agccuucauc     1500

agaaaaucag acgaacuacu acauaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaacaacaa ucauaauagu uaucauagua auacuacuau cucuaauagc ugucggacuc     1620

uuacuauauu gcaaagcccg auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4523
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4523
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccugaaa      120

gccaacgcca uaaccacaau ccuuaccgca gucaccuucu gcuucgccuc cggucaaaac      180

aucacagaag aguucuacca auccaccugu uccgcaguca gcaaaggcua ccucuccgca      240

cuccgaaccg gaugguacac cagcgucauc accaucgaac uauccaacau aaaggaaaau      300

aagugcaaug guacagaugc caaggucaaa cucauaaagc aagaacucga caaauacaaa      360

aacgccguca ccgaacuaca acuacuaaug caaucuaccc ccgcaacagg cucagguucc      420

gccauagccu ccggcgucgc cguuugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gcagucgucu cccucucaaa cggagucucg      540

guccucaccu ucaaaguccu cgaccucaaa aacuauauag acaaacaacu ccuacccaua      600

cucaacaaac aguccugcag cauauccaac aucgaaaccg ugaucgaguu ccaacagaaa      660

aacaacagac uccucgaaau cacucgagag uucuccguaa acgccggcgu cacaacccca      720

gucucaacau acaugcucac caacagcgaa cuccuaucac uaaucaacga caugccuauc      780

acaaaugauc agaagaaacu aaugagcaac aacguccaaa ucguccgcca acaaucauac      840

uccaucaugu gcaucauaaa agaagaaguc cuagccuacg ugguccagcu accccucuac      900

ggcguaauug acaccccuug cuggaaacua cacacuucac cccucugcac aaccaacacc      960

aaagaagguu caaacaucug ccucacacga acagaccgcg gcugguacug cgacaacgcc     1020

ggauccguau ccuucuuccc ccaagcagaa accugcaaag uucaauccaa ccggguauuc     1080

ugcgacacca ugaacucaag aacccuuccc uccgaaguaa aucuaugcaa cgucgacaua     1140

uucaacccaa aauacgacug caaaaucaug accuccaaaa ccgaugucuc cagcagcguc     1200

aucaccagcc ucggcgccau cgucuccugc uacggcaaaa caaaauguac agcauccaac     1260

aaaaaccgag gcauaaucaa aaccuucucc aacgggugcg auuacgucag caacaaaggc     1320

gucgacaccg ucuccguggg caacacccua uacuacguca acaaacaaga aggcaaauca     1380

cuguacguaa agggcgaacc caucaucaac uucuaugacc cucugguguu cccauccgau     1440

gaauuugacg cauccauauc ucaggucaac gaaaagauca accaaucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acacaacguc aacgcuggua aaagcaccac caacaucaug     1560

aucaccacaa ucaucaucgu cauaaucguu auccuacucu cccuuauagc agucggacuc     1620

cuccucuacu gcaaagcccg cuaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  4524
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4524
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4525
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4525
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4526
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4526
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4527
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4527
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4528
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4528
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4529
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4529
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4530
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4530
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauccucaaa      120

gcaaacgcaa uaacaacaau acuaacagca gucacuuucu gcuucgcauc cggacaaaau      180

aucacagaag aauuuuacca auccaccugc ucugcugucu ccaaaggaua ccuaucugcc      240

cucagaaccg guugguauac aucugucaua accauagaac uaucaaacau uaaagaaaac      300

aaauguaacg gaacagacgc aaaagucaaa cuuauaaaac aagaauuaga caaauacaaa      360

aacgcaguca cagaauuaca acuacuaaug caaucaaccc cagcaaccgg aucaggaucc      420

gcaauagcuu caggaguagc aguauguaaa guucuacacu uagaaggaga agucaacaaa      480

auuaaauccg cacuauuauc aaccaacaaa gcagucguau cuuuaucaaa cggaguaucu      540

guacuuacau ucaaaguacu agaccuaaaa aauuacauug auaaacaauu acuaccaaua      600

cuaaacaaac aaucauguuc caucucuaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau cacccgagaa uuuucaguaa acgcaggagu aaccacaccc      720

guaucuacau acaugcuaac aaacucugaa cuucugagcc uaauaaauga caugccaaua      780

accaacgacc aaaaaaaacu aauguccaac aacguacaaa uaguacgaca acaaucuuac      840

ucaaucaugu gcauaaucaa agaagaagua cuagcuuaug uaguccaacu uccacucuac      900

ggaguaauag acacccccug cuggaaacua cacacaucac cacuaugcac aacaaacaca      960

aaagaaggcu caaacauaug ccuaacaaga acugacagag gaugguauug ugacaaugca     1020

ggcucugucu cauucuuucc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacaa ugaacucuag aacucuccca ucagaaguca acuuaugcaa cguugacaua     1140

uucaacccaa aauaugacug uaaaauaaug acuuccaaaa cugauguauc auccuccguc     1200

auaacauccc uaggagcuau uguaucaugu uacgggaaaa ccaaaugcac agccucaaac     1260

aaaaaccgcg guaucauaaa aacauuuuca aacggaugug auuacguaag caauaaagga     1320

guagacaccg uaucaguagg aaauacacua uacuauguaa auaaacaaga aggaaaauca     1380

cuauauguca aaggagaacc aaucauaaau uucuaugacc cacuuguauu cccauccgau     1440

gaauuugacg caagcauuuc acaggucaac gaaaaaauaa accaaucacu agccuucauc     1500

agaaaaucag acgaacuacu acauaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaacaacaa ucauaauagu uaucauagua auacuacuau cucuaauagc ugucggacuc     1620

uuacuauauu gcaaagcccg auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4531
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4531
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccugaaa      120

gccaacgcca uaaccacaau ccuuaccgca gucaccuucu gcuucgccuc cggucaaaac      180

aucacagaag aguucuacca auccaccugu uccgcaguca gcaaaggcua ccucuccgca      240

cuccgaaccg gaugguacac cagcgucauc accaucgaac uauccaacau aaaggaaaau      300

aagugcaaug guacagaugc caaggucaaa cucauaaagc aagaacucga caaauacaaa      360

aacgccguca ccgaacuaca acuacuaaug caaucuaccc ccgcaacagg cucagguucc      420

gccauagccu ccggcgucgc cguuugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gcagucgucu cccucucaaa cggagucucg      540

guccucaccu ucaaaguccu cgaccucaaa aacuauauag acaaacaacu ccuacccaua      600

cucaacaaac aguccugcag cauauccaac aucgaaaccg ugaucgaguu ccaacagaaa      660

aacaacagac uccucgaaau cacucgagag uucuccguaa acgccggcgu cacaacccca      720

gucucaacau acaugcucac caacagcgaa cuccuaucac uaaucaacga caugccuauc      780

acaaaugauc agaagaaacu aaugagcaac aacguccaaa ucguccgcca acaaucauac      840

uccaucaugu gcaucauaaa agaagaaguc cuagccuacg ugguccagcu accccucuac      900

ggcguaauug acaccccuug cuggaaacua cacacuucac cccucugcac aaccaacacc      960

aaagaagguu caaacaucug ccucacacga acagaccgcg gcugguacug cgacaacgcc     1020

ggauccguau ccuucuuccc ccaagcagaa accugcaaag uucaauccaa ccggguauuc     1080

ugcgacacca ugaacucaag aacccuuccc uccgaaguaa aucuaugcaa cgucgacaua     1140

uucaacccaa aauacgacug caaaaucaug accuccaaaa ccgaugucuc cagcagcguc     1200

aucaccagcc ucggcgccau cgucuccugc uacggcaaaa caaaauguac agcauccaac     1260

aaaaaccgag gcauaaucaa aaccuucucc aacgggugcg auuacgucag caacaaaggc     1320

gucgacaccg ucuccguggg caacacccua uacuacguca acaaacaaga aggcaaauca     1380

cuguacguaa agggcgaacc caucaucaac uucuaugacc cucugguguu cccauccgau     1440

gaauuugacg cauccauauc ucaggucaac gaaaagauca accaaucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acacaacguc aacgcuggua aaagcaccac caacaucaug     1560

aucaccacaa ucaucaucgu cauaaucguu auccuacucu cccuuauagc agucggacuc     1620

cuccucuacu gcaaagcccg cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  4532
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4532
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4533
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4533
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacuacguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4534
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4534
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4535
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4535
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucaugcag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu guauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug cuggaaacuu cauacaagcc cacuguguac cacuaauaca      960

aaggagggcu cgaacauuug cuugacccga acggaucgug gcugguacug ugacaaugcc     1020

gggucugugu ccuucuuucc ccaggcugaa accugcaagg uucagucaaa cagaguguuc     1080

ugugauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug caagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagccau cguguccugu uacgguaaga cuaaaugcac agcaagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugug auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuauguua acaagcaaga ggguaaaagc     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaau gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4536
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4536
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4537
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4537
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccugcag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu guaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug cuggaaacug cauacgucuc cucucuguac cacaaauacc      960

aaggaggggu ccaacaucug ccugacacgg accgaucgcg gaugguacug ugacaaugcc     1020

ggcagcgucu cuuucuuucc ccaggcggaa acgugcaagg ugcagagcaa cagaguuuuc     1080

ugugauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug caagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggccau cgugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugug auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga gggcaaaucu     1380

cuguacguga agggggaacc caucauuaac uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaau gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguacu gcaaagcuag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4538
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4538
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauccucaaa      120

gcaaacgcaa uaacaacaau acuaacagca gucacuuucu gcuucgcauc cggacaaaau      180

aucacagaag aauuuuacca auccaccugc ucugcugucu ccaaaggaua ccuaucugcc      240

cucagaaccg guugguauac aucugucaua accauagaac uaucaaacau uaaagaaaac      300

aaauguaacg gaacagacgc aaaagucaaa cuuauaaaac aagaauuaga caaauacaaa      360

aacgcaguca cagaauuaca acuacuaaug caaucaaccc cagcaaccgg aucaggaucc      420

gcaauagcuu caggaguagc aguauguaaa guucuacacu uagaaggaga agucaacaaa      480

auuaaauccg cacuauuauc aaccaacaaa gcagucguau cuuuaucaaa cggaguaucu      540

guacuuacau ucaaaguacu agaccuaaaa aauuacauug auaaacaauu acuaccaaua      600

cuaaacaaac aaucauguuc caucucuaac auagaaacag uaauagaauu ucaacaaaaa      660

aauaacagau uacuugaaau cacccgagaa uuuucaguaa acgcaggagu aaccacaccc      720

guaucuacau acaugcuaac aaacucugaa cuucugagcc uaauaaauga caugccaaua      780

accaacgacc aaaaaaaacu aauguccaac aacguacaaa uaguacgaca acaaucuuac      840

ucaaucaugu gcauaaucaa agaagaagua cuagcuuaug uaguccaacu uccacucuac      900

ggaguaauag acacccccug cuggaaacua cacacaucac cacuaugcac aacaaacaca      960

aaagaaggcu caaacauaug ccuaacaaga acugacagag gaugguauug ugacaaugca     1020

ggcucugucu cauucuuucc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacaa ugaacucuag aacucuccca ucagaaguca acuuaugcaa cguugacaua     1140

uucaacccaa aauaugacug uaaaauaaug acuuccaaaa cugauguauc auccuccguc     1200

auaacauccc uaggagcuau uguaucaugu uacgggaaaa ccaaaugcac agccucaaac     1260

aaaaaccgcg guaucauaaa aacauuuuca aacggaugug auuacguaag caauaaagga     1320

guagacaccg uaucaguagg aaauacacua uacuauguaa auaaacaaga aggaaaauca     1380

cuauauguca aaggagaacc aaucauaaau uucuaugacc cacuuguauu cccauccgau     1440

gaauuugacg caagcauuuc acaggucaac gaaaaaauaa accaaucacu agccuucauc     1500

agaaaaucag acgaacuacu acauaacgua aacgccggaa aaucaacaac caacauaaug     1560

auaacaacaa ucauaauagu uaucauagua auacuacuau cucuaauagc ugucggacuc     1620

uuacuauauu gcaaagcccg auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4539
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4539
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu aauccugaaa      120

gccaacgcca uaaccacaau ccuuaccgca gucaccuucu gcuucgccuc cggucaaaac      180

aucacagaag aguucuacca auccaccugu uccgcaguca gcaaaggcua ccucuccgca      240

cuccgaaccg gaugguacac cagcgucauc accaucgaac uauccaacau aaaggaaaau      300

aagugcaaug guacagaugc caaggucaaa cucauaaagc aagaacucga caaauacaaa      360

aacgccguca ccgaacuaca acuacuaaug caaucuaccc ccgcaacagg cucagguucc      420

gccauagccu ccggcgucgc cguuugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gcagucgucu cccucucaaa cggagucucg      540

guccucaccu ucaaaguccu cgaccucaaa aacuauauag acaaacaacu ccuacccaua      600

cucaacaaac aguccugcag cauauccaac aucgaaaccg ugaucgaguu ccaacagaaa      660

aacaacagac uccucgaaau cacucgagag uucuccguaa acgccggcgu cacaacccca      720

gucucaacau acaugcucac caacagcgaa cuccuaucac uaaucaacga caugccuauc      780

acaaaugauc agaagaaacu aaugagcaac aacguccaaa ucguccgcca acaaucauac      840

uccaucaugu gcaucauaaa agaagaaguc cuagccuacg ugguccagcu accccucuac      900

ggcguaauug acaccccuug cuggaaacua cacacuucac cccucugcac aaccaacacc      960

aaagaagguu caaacaucug ccucacacga acagaccgcg gcugguacug cgacaacgcc     1020

ggauccguau ccuucuuccc ccaagcagaa accugcaaag uucaauccaa ccggguauuc     1080

ugcgacacca ugaacucaag aacccuuccc uccgaaguaa aucuaugcaa cgucgacaua     1140

uucaacccaa aauacgacug caaaaucaug accuccaaaa ccgaugucuc cagcagcguc     1200

aucaccagcc ucggcgccau cgucuccugc uacggcaaaa caaaauguac agcauccaac     1260

aaaaaccgag gcauaaucaa aaccuucucc aacgggugcg auuacgucag caacaaaggc     1320

gucgacaccg ucuccguggg caacacccua uacuacguca acaaacaaga aggcaaauca     1380

cuguacguaa agggcgaacc caucaucaac uucuaugacc cucugguguu cccauccgau     1440

gaauuugacg cauccauauc ucaggucaac gaaaagauca accaaucccu cgccuucaua     1500

cgcaaauccg acgaacuccu acacaacguc aacgcuggua aaagcaccac caacaucaug     1560

aucaccacaa ucaucaucgu cauaaucguu auccuacucu cccuuauagc agucggacuc     1620

cuccucuacu gcaaagcccg cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4540
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4540
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4541
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4541
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4542
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4542
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4543
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4543
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4544
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4544
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4545
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4545
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4546
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4546
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucaucc ucaaagcaaa cgcaauaaca acaauacuaa cagcagucac uuucugcuuc      240

gcauccggac aaaauaucac agaagaauuu uaccaaucca ccugcucugc ugucuccaaa      300

ggauaccuau cugcccucag aaccgguugg uauacaucug ucauaaccau agaacuauca      360

aacauuaaag aaaacaaaug uaacggaaca gacgcaaaag ucaaacuuau aaaacaagaa      420

uuagacaaau acaaaaacgc agucacagaa uuacaacuac uaaugcaauc aaccccagca      480

accggaucag gauccgcaau agcuucagga guagcaguau guaaaguucu acacuuagaa      540

ggagaaguca acaaaauuaa auccgcacua uuaucaacca acaaagcagu cguaucuuua      600

ucaaacggag uaucuguacu uacauucaaa guacuagacc uaaaaaauua cauugauaaa      660

caauuacuac caauacuaaa caaacaauca uguuccaucu cuaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaaucaccc gagaauuuuc aguaaacgca      780

ggaguaacca cacccguauc uacauacaug cuaacaaacu cugaacuucu gagccuaaua      840

aaugacaugc caauaaccaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

cgacaacaau cuuacucaau caugugcaua aucaaagaag aaguacuagc uuauguaguc      960

caacuuccac ucuacggagu aauagacacc cccugcugga aacuacacac aucaccacua     1020

ugcacaacaa acacaaaaga aggcucaaac auaugccuaa caagaacuga cagaggaugg     1080

uauugugaca augcaggcuc ugucucauuc uuuccacaag ccgaaacaug caaaguucaa     1140

ucaaaccgag uuuucuguga cacaaugaac ucuagaacuc ucccaucaga agucaacuua     1200

ugcaacguug acauauucaa cccaaaauau gacuguaaaa uaaugacuuc caaaacugau     1260

guaucauccu ccgucauaac aucccuagga gcuauuguau cauguuacgg gaaaaccaaa     1320

ugcacagccu caaacaaaaa ccgcgguauc auaaaaacau uuucaaacgg augugauuac     1380

guaagcaaua aaggaguaga caccguauca guaggaaaua cacuauacua uguaaauaaa     1440

caagaaggaa aaucacuaua ugucaaagga gaaccaauca uaaauuucua ugacccacuu     1500

guauucccau ccgaugaauu ugacgcaagc auuucacagg ucaacgaaaa aauaaaccaa     1560

ucacuagccu ucaucagaaa aucagacgaa cuacuacaua acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac aacaaucaua auaguuauca uaguaauacu acuaucucua     1680

auagcugucg gacucuuacu auauugcaaa gcccgauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4547
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4547
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc ugaaagccaa cgccauaacc acaauccuua ccgcagucac cuucugcuuc      240

gccuccgguc aaaacaucac agaagaguuc uaccaaucca ccuguuccgc agucagcaaa      300

ggcuaccucu ccgcacuccg aaccggaugg uacaccagcg ucaucaccau cgaacuaucc      360

aacauaaagg aaaauaagug caaugguaca gaugccaagg ucaaacucau aaagcaagaa      420

cucgacaaau acaaaaacgc cgucaccgaa cuacaacuac uaaugcaauc uacccccgca      480

acaggcucag guuccgccau agccuccggc gucgccguuu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa auccgcccua cucucaacca acaaagcagu cgucucccuc      600

ucaaacggag ucucgguccu caccuucaaa guccucgacc ucaaaaacua uauagacaaa      660

caacuccuac ccauacucaa caaacagucc ugcagcauau ccaacaucga aaccgugauc      720

gaguuccaac agaaaaacaa cagacuccuc gaaaucacuc gagaguucuc cguaaacgcc      780

ggcgucacaa ccccagucuc aacauacaug cucaccaaca gcgaacuccu aucacuaauc      840

aacgacaugc cuaucacaaa ugaucagaag aaacuaauga gcaacaacgu ccaaaucguc      900

cgccaacaau cauacuccau caugugcauc auaaaagaag aaguccuagc cuacgugguc      960

cagcuacccc ucuacggcgu aauugacacc ccuugcugga aacuacacac uucaccccuc     1020

ugcacaacca acaccaaaga agguucaaac aucugccuca cacgaacaga ccgcggcugg     1080

uacugcgaca acgccggauc cguauccuuc uucccccaag cagaaaccug caaaguucaa     1140

uccaaccggg uauucugcga caccaugaac ucaagaaccc uucccuccga aguaaaucua     1200

ugcaacgucg acauauucaa cccaaaauac gacugcaaaa ucaugaccuc caaaaccgau     1260

gucuccagca gcgucaucac cagccucggc gccaucgucu ccugcuacgg caaaacaaaa     1320

uguacagcau ccaacaaaaa ccgaggcaua aucaaaaccu ucuccaacgg gugcgauuac     1380

gucagcaaca aaggcgucga caccgucucc gugggcaaca cccuauacua cgucaacaaa     1440

caagaaggca aaucacugua cguaaagggc gaacccauca ucaacuucua ugacccucug     1500

guguucccau ccgaugaauu ugacgcaucc auaucucagg ucaacgaaaa gaucaaccaa     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaca acgucaacgc ugguaaaagc     1620

accaccaaca ucaugaucac cacaaucauc aucgucauaa ucguuauccu acucucccuu     1680

auagcagucg gacuccuccu cuacugcaaa gcccgcuaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4548
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4548
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4549
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4549
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4550
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4550
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4551
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4551
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4552
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4552
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4553
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4553
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4554
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4554
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucaucc ucaaagcaaa cgcaauaaca acaauacuaa cagcagucac uuucugcuuc      240

gcauccggac aaaauaucac agaagaauuu uaccaaucca ccugcucugc ugucuccaaa      300

ggauaccuau cugcccucag aaccgguugg uauacaucug ucauaaccau agaacuauca      360

aacauuaaag aaaacaaaug uaacggaaca gacgcaaaag ucaaacuuau aaaacaagaa      420

uuagacaaau acaaaaacgc agucacagaa uuacaacuac uaaugcaauc aaccccagca      480

accggaucag gauccgcaau agcuucagga guagcaguau guaaaguucu acacuuagaa      540

ggagaaguca acaaaauuaa auccgcacua uuaucaacca acaaagcagu cguaucuuua      600

ucaaacggag uaucuguacu uacauucaaa guacuagacc uaaaaaauua cauugauaaa      660

caauuacuac caauacuaaa caaacaauca uguuccaucu cuaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaaucaccc gagaauuuuc aguaaacgca      780

ggaguaacca cacccguauc uacauacaug cuaacaaacu cugaacuucu gagccuaaua      840

aaugacaugc caauaaccaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

cgacaacaau cuuacucaau caugugcaua aucaaagaag aaguacuagc uuauguaguc      960

caacuuccac ucuacggagu aauagacacc cccugcugga aacuacacac aucaccacua     1020

ugcacaacaa acacaaaaga aggcucaaac auaugccuaa caagaacuga cagaggaugg     1080

uauugugaca augcaggcuc ugucucauuc uuuccacaag ccgaaacaug caaaguucaa     1140

ucaaaccgag uuuucuguga cacaaugaac ucuagaacuc ucccaucaga agucaacuua     1200

ugcaacguug acauauucaa cccaaaauau gacuguaaaa uaaugacuuc caaaacugau     1260

guaucauccu ccgucauaac aucccuagga gcuauuguau cauguuacgg gaaaaccaaa     1320

ugcacagccu caaacaaaaa ccgcgguauc auaaaaacau uuucaaacgg augugauuac     1380

guaagcaaua aaggaguaga caccguauca guaggaaaua cacuauacua uguaaauaaa     1440

caagaaggaa aaucacuaua ugucaaagga gaaccaauca uaaauuucua ugacccacuu     1500

guauucccau ccgaugaauu ugacgcaagc auuucacagg ucaacgaaaa aauaaaccaa     1560

ucacuagccu ucaucagaaa aucagacgaa cuacuacaua acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac aacaaucaua auaguuauca uaguaauacu acuaucucua     1680

auagcugucg gacucuuacu auauugcaaa gcccgauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4555
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4555
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc ugaaagccaa cgccauaacc acaauccuua ccgcagucac cuucugcuuc      240

gccuccgguc aaaacaucac agaagaguuc uaccaaucca ccuguuccgc agucagcaaa      300

ggcuaccucu ccgcacuccg aaccggaugg uacaccagcg ucaucaccau cgaacuaucc      360

aacauaaagg aaaauaagug caaugguaca gaugccaagg ucaaacucau aaagcaagaa      420

cucgacaaau acaaaaacgc cgucaccgaa cuacaacuac uaaugcaauc uacccccgca      480

acaggcucag guuccgccau agccuccggc gucgccguuu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa auccgcccua cucucaacca acaaagcagu cgucucccuc      600

ucaaacggag ucucgguccu caccuucaaa guccucgacc ucaaaaacua uauagacaaa      660

caacuccuac ccauacucaa caaacagucc ugcagcauau ccaacaucga aaccgugauc      720

gaguuccaac agaaaaacaa cagacuccuc gaaaucacuc gagaguucuc cguaaacgcc      780

ggcgucacaa ccccagucuc aacauacaug cucaccaaca gcgaacuccu aucacuaauc      840

aacgacaugc cuaucacaaa ugaucagaag aaacuaauga gcaacaacgu ccaaaucguc      900

cgccaacaau cauacuccau caugugcauc auaaaagaag aaguccuagc cuacgugguc      960

cagcuacccc ucuacggcgu aauugacacc ccuugcugga aacuacacac uucaccccuc     1020

ugcacaacca acaccaaaga agguucaaac aucugccuca cacgaacaga ccgcggcugg     1080

uacugcgaca acgccggauc cguauccuuc uucccccaag cagaaaccug caaaguucaa     1140

uccaaccggg uauucugcga caccaugaac ucaagaaccc uucccuccga aguaaaucua     1200

ugcaacgucg acauauucaa cccaaaauac gacugcaaaa ucaugaccuc caaaaccgau     1260

gucuccagca gcgucaucac cagccucggc gccaucgucu ccugcuacgg caaaacaaaa     1320

uguacagcau ccaacaaaaa ccgaggcaua aucaaaaccu ucuccaacgg gugcgauuac     1380

gucagcaaca aaggcgucga caccgucucc gugggcaaca cccuauacua cgucaacaaa     1440

caagaaggca aaucacugua cguaaagggc gaacccauca ucaacuucua ugacccucug     1500

guguucccau ccgaugaauu ugacgcaucc auaucucagg ucaacgaaaa gaucaaccaa     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaca acgucaacgc ugguaaaagc     1620

accaccaaca ucaugaucac cacaaucauc aucgucauaa ucguuauccu acucucccuu     1680

auagcagucg gacuccuccu cuacugcaaa gcccgcuaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  4556
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4556
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4557
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4557
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacua cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgcgu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4558
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4558
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4559
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4559
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca ugcaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau cauguguauu auaaaggagg aaguguuagc auauguagug      960

caacugcccc ucuacggagu caucgacacu ccuugcugga aacuucauac aagcccacug     1020

uguaccacua auacaaagga gggcucgaac auuugcuuga cccgaacgga ucguggcugg     1080

uacugugaca augccggguc uguguccuuc uuuccccagg cugaaaccug caagguucag     1140

ucaaacagag uguucuguga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauugcaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gccaucgugu ccuguuacgg uaagacuaaa     1320

ugcacagcaa gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugugauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacua uguuaacaag     1440

caagagggua aaagccugua cgugaagggg gaacccauca uuaacuuuua ugacccuuug     1500

guauucccau ccgaugaguu ugacgcuucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgccu ucauucggaa guccgaugaa cuguuacaca augugaacgc gggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgccgucg gccugcuuuu guacugcaaa gcacgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4560
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4560
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4561
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4561
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc ugcagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uauguguauc auuaaggagg aaguccuggc uuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccugcugga aacugcauac gucuccucuc     1020

uguaccacaa auaccaagga gggguccaac aucugccuga cacggaccga ucgcggaugg     1080

uacugugaca augccggcag cgucucuuuc uuuccccagg cggaaacgug caaggugcag     1140

agcaacagag uuuucuguga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauugcaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gccaucguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugugauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacua uguuaacaag     1440

caagagggca aaucucugua cgugaagggg gaacccauca uuaacuuuua ugacccucuc     1500

gucuucccca gcgaugaguu ugacgccucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggcuu ucauccgcaa guccgaugaa cugcuccaca augugaacgc cggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guacugcaaa gcuagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4562
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4562
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucaucc ucaaagcaaa cgcaauaaca acaauacuaa cagcagucac uuucugcuuc      240

gcauccggac aaaauaucac agaagaauuu uaccaaucca ccugcucugc ugucuccaaa      300

ggauaccuau cugcccucag aaccgguugg uauacaucug ucauaaccau agaacuauca      360

aacauuaaag aaaacaaaug uaacggaaca gacgcaaaag ucaaacuuau aaaacaagaa      420

uuagacaaau acaaaaacgc agucacagaa uuacaacuac uaaugcaauc aaccccagca      480

accggaucag gauccgcaau agcuucagga guagcaguau guaaaguucu acacuuagaa      540

ggagaaguca acaaaauuaa auccgcacua uuaucaacca acaaagcagu cguaucuuua      600

ucaaacggag uaucuguacu uacauucaaa guacuagacc uaaaaaauua cauugauaaa      660

caauuacuac caauacuaaa caaacaauca uguuccaucu cuaacauaga aacaguaaua      720

gaauuucaac aaaaaaauaa cagauuacuu gaaaucaccc gagaauuuuc aguaaacgca      780

ggaguaacca cacccguauc uacauacaug cuaacaaacu cugaacuucu gagccuaaua      840

aaugacaugc caauaaccaa cgaccaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

cgacaacaau cuuacucaau caugugcaua aucaaagaag aaguacuagc uuauguaguc      960

caacuuccac ucuacggagu aauagacacc cccugcugga aacuacacac aucaccacua     1020

ugcacaacaa acacaaaaga aggcucaaac auaugccuaa caagaacuga cagaggaugg     1080

uauugugaca augcaggcuc ugucucauuc uuuccacaag ccgaaacaug caaaguucaa     1140

ucaaaccgag uuuucuguga cacaaugaac ucuagaacuc ucccaucaga agucaacuua     1200

ugcaacguug acauauucaa cccaaaauau gacuguaaaa uaaugacuuc caaaacugau     1260

guaucauccu ccgucauaac aucccuagga gcuauuguau cauguuacgg gaaaaccaaa     1320

ugcacagccu caaacaaaaa ccgcgguauc auaaaaacau uuucaaacgg augugauuac     1380

guaagcaaua aaggaguaga caccguauca guaggaaaua cacuauacua uguaaauaaa     1440

caagaaggaa aaucacuaua ugucaaagga gaaccaauca uaaauuucua ugacccacuu     1500

guauucccau ccgaugaauu ugacgcaagc auuucacagg ucaacgaaaa aauaaaccaa     1560

ucacuagccu ucaucagaaa aucagacgaa cuacuacaua acguaaacgc cggaaaauca     1620

acaaccaaca uaaugauaac aacaaucaua auaguuauca uaguaauacu acuaucucua     1680

auagcugucg gacucuuacu auauugcaaa gcccgauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4563
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4563
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacuaaucc ugaaagccaa cgccauaacc acaauccuua ccgcagucac cuucugcuuc      240

gccuccgguc aaaacaucac agaagaguuc uaccaaucca ccuguuccgc agucagcaaa      300

ggcuaccucu ccgcacuccg aaccggaugg uacaccagcg ucaucaccau cgaacuaucc      360

aacauaaagg aaaauaagug caaugguaca gaugccaagg ucaaacucau aaagcaagaa      420

cucgacaaau acaaaaacgc cgucaccgaa cuacaacuac uaaugcaauc uacccccgca      480

acaggcucag guuccgccau agccuccggc gucgccguuu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa auccgcccua cucucaacca acaaagcagu cgucucccuc      600

ucaaacggag ucucgguccu caccuucaaa guccucgacc ucaaaaacua uauagacaaa      660

caacuccuac ccauacucaa caaacagucc ugcagcauau ccaacaucga aaccgugauc      720

gaguuccaac agaaaaacaa cagacuccuc gaaaucacuc gagaguucuc cguaaacgcc      780

ggcgucacaa ccccagucuc aacauacaug cucaccaaca gcgaacuccu aucacuaauc      840

aacgacaugc cuaucacaaa ugaucagaag aaacuaauga gcaacaacgu ccaaaucguc      900

cgccaacaau cauacuccau caugugcauc auaaaagaag aaguccuagc cuacgugguc      960

cagcuacccc ucuacggcgu aauugacacc ccuugcugga aacuacacac uucaccccuc     1020

ugcacaacca acaccaaaga agguucaaac aucugccuca cacgaacaga ccgcggcugg     1080

uacugcgaca acgccggauc cguauccuuc uucccccaag cagaaaccug caaaguucaa     1140

uccaaccggg uauucugcga caccaugaac ucaagaaccc uucccuccga aguaaaucua     1200

ugcaacgucg acauauucaa cccaaaauac gacugcaaaa ucaugaccuc caaaaccgau     1260

gucuccagca gcgucaucac cagccucggc gccaucgucu ccugcuacgg caaaacaaaa     1320

uguacagcau ccaacaaaaa ccgaggcaua aucaaaaccu ucuccaacgg gugcgauuac     1380

gucagcaaca aaggcgucga caccgucucc gugggcaaca cccuauacua cgucaacaaa     1440

caagaaggca aaucacugua cguaaagggc gaacccauca ucaacuucua ugacccucug     1500

guguucccau ccgaugaauu ugacgcaucc auaucucagg ucaacgaaaa gaucaaccaa     1560

ucccucgccu ucauacgcaa auccgacgaa cuccuacaca acgucaacgc ugguaaaagc     1620

accaccaaca ucaugaucac cacaaucauc aucgucauaa ucguuauccu acucucccuu     1680

auagcagucg gacuccuccu cuacugcaaa gcccgcuaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4564
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4564
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4565
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4565
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cuacgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4566
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4566
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4567
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4567
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucaugcagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugu auuauaaagg aggaaguguu agcauaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuugcu ggaaacuuca uacaagccca      900

cuguguacca cuaauacaaa ggagggcucg aacauuugcu ugacccgaac ggaucguggc      960

ugguacugug acaaugccgg gucugugucc uucuuucccc aggcugaaac cugcaagguu     1020

cagucaaaca gaguguucug ugauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugca agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagccaucg uguccuguua cgguaagacu     1200

aaaugcacag caagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugugau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuauguuaac     1320

aagcaagagg guaaaagccu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4568
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4568
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4569
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4569
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccugcagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugu aucauuaagg aggaaguccu ggcuuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccugcu ggaaacugca uacgucuccu      900

cucuguacca caaauaccaa ggaggggucc aacaucugcc ugacacggac cgaucgcgga      960

ugguacugug acaaugccgg cagcgucucu uucuuucccc aggcggaaac gugcaaggug     1020

cagagcaaca gaguuuucug ugauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugca agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggccaucg ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugugau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuauguuaac     1320

aagcaagagg gcaaaucucu guacgugaag ggggaaccca ucauuaacuu uuaugacccu     1380

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguacugc aaagcuagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4570
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4570
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaauuacuca uccucaaagc aaacgcaaua acaacaauac uaacagcagu cacuuucugc      120

uucgcauccg gacaaaauau cacagaagaa uuuuaccaau ccaccugcuc ugcugucucc      180

aaaggauacc uaucugcccu cagaaccggu ugguauacau cugucauaac cauagaacua      240

ucaaacauua aagaaaacaa auguaacgga acagacgcaa aagucaaacu uauaaaacaa      300

gaauuagaca aauacaaaaa cgcagucaca gaauuacaac uacuaaugca aucaacccca      360

gcaaccggau caggauccgc aauagcuuca ggaguagcag uauguaaagu ucuacacuua      420

gaaggagaag ucaacaaaau uaaauccgca cuauuaucaa ccaacaaagc agucguaucu      480

uuaucaaacg gaguaucugu acuuacauuc aaaguacuag accuaaaaaa uuacauugau      540

aaacaauuac uaccaauacu aaacaaacaa ucauguucca ucucuaacau agaaacagua      600

auagaauuuc aacaaaaaaa uaacagauua cuugaaauca cccgagaauu uucaguaaac      660

gcaggaguaa ccacacccgu aucuacauac augcuaacaa acucugaacu ucugagccua      720

auaaaugaca ugccaauaac caacgaccaa aaaaaacuaa uguccaacaa cguacaaaua      780

guacgacaac aaucuuacuc aaucaugugc auaaucaaag aagaaguacu agcuuaugua      840

guccaacuuc cacucuacgg aguaauagac acccccugcu ggaaacuaca cacaucacca      900

cuaugcacaa caaacacaaa agaaggcuca aacauaugcc uaacaagaac ugacagagga      960

ugguauugug acaaugcagg cucugucuca uucuuuccac aagccgaaac augcaaaguu     1020

caaucaaacc gaguuuucug ugacacaaug aacucuagaa cucucccauc agaagucaac     1080

uuaugcaacg uugacauauu caacccaaaa uaugacugua aaauaaugac uuccaaaacu     1140

gauguaucau ccuccgucau aacaucccua ggagcuauug uaucauguua cgggaaaacc     1200

aaaugcacag ccucaaacaa aaaccgcggu aucauaaaaa cauuuucaaa cggaugugau     1260

uacguaagca auaaaggagu agacaccgua ucaguaggaa auacacuaua cuauguaaau     1320

aaacaagaag gaaaaucacu auaugucaaa ggagaaccaa ucauaaauuu cuaugaccca     1380

cuuguauucc cauccgauga auuugacgca agcauuucac aggucaacga aaaaauaaac     1440

caaucacuag ccuucaucag aaaaucagac gaacuacuac auaacguaaa cgccggaaaa     1500

ucaacaacca acauaaugau aacaacaauc auaauaguua ucauaguaau acuacuaucu     1560

cuaauagcug ucggacucuu acuauauugc aaagcccgau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4571
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4571
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuaa uccugaaagc caacgccaua accacaaucc uuaccgcagu caccuucugc      120

uucgccuccg gucaaaacau cacagaagag uucuaccaau ccaccuguuc cgcagucagc      180

aaaggcuacc ucuccgcacu ccgaaccgga ugguacacca gcgucaucac caucgaacua      240

uccaacauaa aggaaaauaa gugcaauggu acagaugcca aggucaaacu cauaaagcaa      300

gaacucgaca aauacaaaaa cgccgucacc gaacuacaac uacuaaugca aucuaccccc      360

gcaacaggcu cagguuccgc cauagccucc ggcgucgccg uuugcaaagu ccuccaccuc      420

gaaggcgaag uaaacaaaau caaauccgcc cuacucucaa ccaacaaagc agucgucucc      480

cucucaaacg gagucucggu ccucaccuuc aaaguccucg accucaaaaa cuauauagac      540

aaacaacucc uacccauacu caacaaacag uccugcagca uauccaacau cgaaaccgug      600

aucgaguucc aacagaaaaa caacagacuc cucgaaauca cucgagaguu cuccguaaac      660

gccggcguca caaccccagu cucaacauac augcucacca acagcgaacu ccuaucacua      720

aucaacgaca ugccuaucac aaaugaucag aagaaacuaa ugagcaacaa cguccaaauc      780

guccgccaac aaucauacuc caucaugugc aucauaaaag aagaaguccu agccuacgug      840

guccagcuac cccucuacgg cguaauugac accccuugcu ggaaacuaca cacuucaccc      900

cucugcacaa ccaacaccaa agaagguuca aacaucugcc ucacacgaac agaccgcggc      960

ugguacugcg acaacgccgg auccguaucc uucuuccccc aagcagaaac cugcaaaguu     1020

caauccaacc ggguauucug cgacaccaug aacucaagaa cccuucccuc cgaaguaaau     1080

cuaugcaacg ucgacauauu caacccaaaa uacgacugca aaaucaugac cuccaaaacc     1140

gaugucucca gcagcgucau caccagccuc ggcgccaucg ucuccugcua cggcaaaaca     1200

aaauguacag cauccaacaa aaaccgaggc auaaucaaaa ccuucuccaa cgggugcgau     1260

uacgucagca acaaaggcgu cgacaccguc uccgugggca acacccuaua cuacgucaac     1320

aaacaagaag gcaaaucacu guacguaaag ggcgaaccca ucaucaacuu cuaugacccu     1380

cugguguucc cauccgauga auuugacgca uccauaucuc aggucaacga aaagaucaac     1440

caaucccucg ccuucauacg caaauccgac gaacuccuac acaacgucaa cgcugguaaa     1500

agcaccacca acaucaugau caccacaauc aucaucguca uaaucguuau ccuacucucc     1560

cuuauagcag ucggacuccu ccucuacugc aaagcccgcu aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  4572
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4572
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4573
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4573
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug caccucgagg      420

gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug gucucccuca      480

gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac cggggguggu      960

acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag gucaaccugu     1080

gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg aagaccaagu     1200

gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg ugcgacuacg     1260

ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacuac gucaacaagc     1320

aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc gggaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg ccuccugcug uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4574
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4574
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac gucaacaagc     1320

aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4575
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4575
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug caccucgagg      420

gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug gucucucuca      480

gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac auugauaaac      540

aauugcugcc uauccuaaac aagcagucau gcaguauuag caauaucgag accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu gucaacgcgg      660

gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug agccucauca      720

acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc cagaucguuc      780

gccagcaguc uuacuccauc auguguauua uaaaggagga aguguuagca uauguagugc      840

aacugccccu cuacggaguc aucgacacuc cuugcuggaa acuucauaca agcccacugu      900

guaccacuaa uacaaaggag ggcucgaaca uuugcuugac ccgaacggau cguggcuggu      960

acugugacaa ugccgggucu guguccuucu uuccccaggc ugaaaccugc aagguucagu     1020

caaacagagu guucugugau acaaugaaua guagaacucu gccuagcgag gucaaccucu     1080

gcaaugugga caucuuuaac ccaaaauaug auugcaagau aaugaccucc aaaacagacg     1140

uaucuagcuc aguuauuacc agucugggag ccaucguguc cuguuacggu aagacuaaau     1200

gcacagcaag caauaagaac aggggcauca uuaagaccuu cucuaauggg ugugauuaug     1260

ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacuau guuaacaagc     1320

aagaggguaa aagccuguac gugaaggggg aacccaucau uaacuuuuau gacccuuugg     1380

uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caaugagaaa aucaaccaga     1440

gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg ggaaagucaa     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaagucuca     1560

ucgccgucgg ccugcuuuug uacugcaaag cacgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4576
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4576
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4577
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4577
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc caccuggagg      420

gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc gugucccuca      480

gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac auugauaaac      540

aacuccugcc uauccugaac aagcaguccu gcagcauuuc uaauaucgag accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc gugaacgccg      660

gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc ucucugauca      720

acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug cagaucguga      780

gacagcaguc cuacagcauu auguguauca uuaaggagga aguccuggcu uaugugguuc      840

aacucccucu guacggcgug aucgacacac ccugcuggaa acugcauacg ucuccucucu      900

guaccacaaa uaccaaggag ggguccaaca ucugccugac acggaccgau cgcggauggu      960

acugugacaa ugccggcagc gucucuuucu uuccccaggc ggaaacgugc aaggugcaga     1020

gcaacagagu uuucugugau acaaugaacu ccagaacccu gccuucugag gugaaucucu     1080

gcaaugucga cauuuuuaac ccgaaauaug auugcaagau caugaccagc aaaacagacg     1140

uguccagcuc ugucauuacc ucccuggggg ccaucgugag cuguuacgga aagacaaaau     1200

gcacggcuuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg ugugauuaug     1260

uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacuau guuaacaagc     1320

aagagggcaa aucucuguac gugaaggggg aacccaucau uaacuuuuau gacccucucg     1380

ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaaugagaaa auuaaccaga     1440

gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc ggaaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucucuga     1560

ucgccguggg ccuccugcug uacugcaaag cuagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4578
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4578
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaau       60

uacucauccu caaagcaaac gcaauaacaa caauacuaac agcagucacu uucugcuucg      120

cauccggaca aaauaucaca gaagaauuuu accaauccac cugcucugcu gucuccaaag      180

gauaccuauc ugcccucaga accgguuggu auacaucugu cauaaccaua gaacuaucaa      240

acauuaaaga aaacaaaugu aacggaacag acgcaaaagu caaacuuaua aaacaagaau      300

uagacaaaua caaaaacgca gucacagaau uacaacuacu aaugcaauca accccagcaa      360

ccggaucagg auccgcaaua gcuucaggag uagcaguaug uaaaguucua cacuuagaag      420

gagaagucaa caaaauuaaa uccgcacuau uaucaaccaa caaagcaguc guaucuuuau      480

caaacggagu aucuguacuu acauucaaag uacuagaccu aaaaaauuac auugauaaac      540

aauuacuacc aauacuaaac aaacaaucau guuccaucuc uaacauagaa acaguaauag      600

aauuucaaca aaaaaauaac agauuacuug aaaucacccg agaauuuuca guaaacgcag      660

gaguaaccac acccguaucu acauacaugc uaacaaacuc ugaacuucug agccuaauaa      720

augacaugcc aauaaccaac gaccaaaaaa aacuaauguc caacaacgua caaauaguac      780

gacaacaauc uuacucaauc augugcauaa ucaaagaaga aguacuagcu uauguagucc      840

aacuuccacu cuacggagua auagacaccc ccugcuggaa acuacacaca ucaccacuau      900

gcacaacaaa cacaaaagaa ggcucaaaca uaugccuaac aagaacugac agaggauggu      960

auugugacaa ugcaggcucu gucucauucu uuccacaagc cgaaacaugc aaaguucaau     1020

caaaccgagu uuucugugac acaaugaacu cuagaacucu cccaucagaa gucaacuuau     1080

gcaacguuga cauauucaac ccaaaauaug acuguaaaau aaugacuucc aaaacugaug     1140

uaucauccuc cgucauaaca ucccuaggag cuauuguauc auguuacggg aaaaccaaau     1200

gcacagccuc aaacaaaaac cgcgguauca uaaaaacauu uucaaacgga ugugauuacg     1260

uaagcaauaa aggaguagac accguaucag uaggaaauac acuauacuau guaaauaaac     1320

aagaaggaaa aucacuauau gucaaaggag aaccaaucau aaauuucuau gacccacuug     1380

uauucccauc cgaugaauuu gacgcaagca uuucacaggu caacgaaaaa auaaaccaau     1440

cacuagccuu caucagaaaa ucagacgaac uacuacauaa cguaaacgcc ggaaaaucaa     1500

caaccaacau aaugauaaca acaaucauaa uaguuaucau aguaauacua cuaucucuaa     1560

uagcugucgg acucuuacua uauugcaaag cccgauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4579
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4579
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacuaauccu gaaagccaac gccauaacca caauccuuac cgcagucacc uucugcuucg      120

ccuccgguca aaacaucaca gaagaguucu accaauccac cuguuccgca gucagcaaag      180

gcuaccucuc cgcacuccga accggauggu acaccagcgu caucaccauc gaacuaucca      240

acauaaagga aaauaagugc aaugguacag augccaaggu caaacucaua aagcaagaac      300

ucgacaaaua caaaaacgcc gucaccgaac uacaacuacu aaugcaaucu acccccgcaa      360

caggcucagg uuccgccaua gccuccggcg ucgccguuug caaaguccuc caccucgaag      420

gcgaaguaaa caaaaucaaa uccgcccuac ucucaaccaa caaagcaguc gucucccucu      480

caaacggagu cucgguccuc accuucaaag uccucgaccu caaaaacuau auagacaaac      540

aacuccuacc cauacucaac aaacaguccu gcagcauauc caacaucgaa accgugaucg      600

aguuccaaca gaaaaacaac agacuccucg aaaucacucg agaguucucc guaaacgccg      660

gcgucacaac cccagucuca acauacaugc ucaccaacag cgaacuccua ucacuaauca      720

acgacaugcc uaucacaaau gaucagaaga aacuaaugag caacaacguc caaaucgucc      780

gccaacaauc auacuccauc augugcauca uaaaagaaga aguccuagcc uacguggucc      840

agcuaccccu cuacggcgua auugacaccc cuugcuggaa acuacacacu ucaccccucu      900

gcacaaccaa caccaaagaa gguucaaaca ucugccucac acgaacagac cgcggcuggu      960

acugcgacaa cgccggaucc guauccuucu ucccccaagc agaaaccugc aaaguucaau     1020

ccaaccgggu auucugcgac accaugaacu caagaacccu ucccuccgaa guaaaucuau     1080

gcaacgucga cauauucaac ccaaaauacg acugcaaaau caugaccucc aaaaccgaug     1140

ucuccagcag cgucaucacc agccucggcg ccaucgucuc cugcuacggc aaaacaaaau     1200

guacagcauc caacaaaaac cgaggcauaa ucaaaaccuu cuccaacggg ugcgauuacg     1260

ucagcaacaa aggcgucgac accgucuccg ugggcaacac ccuauacuac gucaacaaac     1320

aagaaggcaa aucacuguac guaaagggcg aacccaucau caacuucuau gacccucugg     1380

uguucccauc cgaugaauuu gacgcaucca uaucucaggu caacgaaaag aucaaccaau     1440

cccucgccuu cauacgcaaa uccgacgaac uccuacacaa cgucaacgcu gguaaaagca     1500

ccaccaacau caugaucacc acaaucauca ucgucauaau cguuauccua cucucccuua     1560

uagcagucgg acuccuccuc uacugcaaag cccgcuaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  4580
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1) R7455

<400>  4580
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

agcaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccggacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4581
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt1)

<400>  4581
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccggcagc ggguccgcca ucgccagcgg cguggcggug      360

ugcaaggucc ugcaccucga gggcgaggug aacaagauca aguccgcccu gcugagcacc      420

aacaaggccg uggucucccu cagcaacggg guguccgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcagag cugcuccauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggcgucacc acgcccguga gcaccuacau gcucaccaac      660

agcgagcugc ugucccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccc cuguacgggg ugaucgacac gccgugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggcuccaa caucugccug      900

acccgcaccg accgggggug guacugcgac aacgcgggcu ccgugagcuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccggacc     1020

cuccccuccg aggucaaccu gugcaacgug gacaucuuca acccgaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg cgccaucgug     1140

uccugcuacg ggaagaccaa gugcaccgcc agcaacaaga accggggcau caucaagacc     1200

uucuccaacg ggugcgacua cgugagcaac aagggcgucg acacggugag cgugggcaac     1260

acccucuacu acgucaacaa gcaggagggg aagucccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcg uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg ccgggaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug ggccuccugc uguacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4582
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt2)

<400>  4582
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

uccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccgcacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu acgucaacaa gcaggagggc aagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4583
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt3)

<400>  4583
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccggcucg gggucagcua uagcaagcgg aguggccguc      360

uguaaggugu ugcaccucga gggcgaaguu aacaaaauca agagugcucu gcuguccacg      420

aauaaagccg uggucucucu cagcaacggu guguccguau uaacuuuuaa gguucuggac      480

cuuaagaauu acauugauaa acaauugcug ccuauccuaa acaagcaguc augcaguauu      540

agcaauaucg agaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuuu cugucaacgc gggggugacu accccagugu ccacauauau gcuuaccaau      660

ucagaacugu ugagccucau caacgacaug ccgauuacga acgaucaaaa gaaacugaug      720

aguaauaacg uccagaucgu ucgccagcag ucuuacucca ucauguguau uauaaaggag      780

gaaguguuag cauauguagu gcaacugccc cucuacggag ucaucgacac uccuugcugg      840

aaacuucaua caagcccacu guguaccacu aauacaaagg agggcucgaa cauuugcuug      900

acccgaacgg aucguggcug guacugugac aaugccgggu cuguguccuu cuuuccccag      960

gcugaaaccu gcaagguuca gucaaacaga guguucugug auacaaugaa uaguagaacu     1020

cugccuagcg aggucaaccu cugcaaugug gacaucuuua acccaaaaua ugauugcaag     1080

auaaugaccu ccaaaacaga cguaucuagc ucaguuauua ccagucuggg agccaucgug     1140

uccuguuacg guaagacuaa augcacagca agcaauaaga acaggggcau cauuaagacc     1200

uucucuaaug ggugugauua ugucucaaac aaaggagugg acacugucag ugugggcaau     1260

acgcuuuacu auguuaacaa gcaagagggu aaaagccugu acgugaaggg ggaacccauc     1320

auuaacuuuu augacccuuu gguauuccca uccgaugagu uugacgcuuc uauaucgcag     1380

gucaaugaga aaaucaacca gagccucgcc uucauucgga aguccgauga acuguuacac     1440

aaugugaacg cgggaaaguc aacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaagucu caucgccguc ggccugcuuu uguacugcaa agcacgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4584
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt4)

<400>  4584
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagcagaacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4585
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt5)

<400>  4585
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacagggucu ggaagcgcua uugccuccgg cgucgcggug      360

uguaagguuc uccaccugga gggggaagug aacaaaauca agagcgcccu ucugucuacc      420

aauaaagcug ucgugucccu cagcaacgga guuucugugc ugacauuuaa gguccuugac      480

cugaagaauu acauugauaa acaacuccug ccuauccuga acaagcaguc cugcagcauu      540

ucuaauaucg agaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuuu ccgugaacgc cggcgucaca accccgguua gcacauauau gcuuaccaau      660

uccgaacugc ucucucugau caacgacaug cccauuacca acgaucaaaa gaaacuuaug      720

agcaauaacg ugcagaucgu gagacagcag uccuacagca uuauguguau cauuaaggag      780

gaaguccugg cuuauguggu ucaacucccu cuguacggcg ugaucgacac acccugcugg      840

aaacugcaua cgucuccucu cuguaccaca aauaccaagg agggguccaa caucugccug      900

acacggaccg aucgcggaug guacugugac aaugccggca gcgucucuuu cuuuccccag      960

gcggaaacgu gcaaggugca gagcaacaga guuuucugug auacaaugaa cuccagaacc     1020

cugccuucug aggugaaucu cugcaauguc gacauuuuua acccgaaaua ugauugcaag     1080

aucaugacca gcaaaacaga cguguccagc ucugucauua ccucccuggg ggccaucgug     1140

agcuguuacg gaaagacaaa augcacggcu ucuaauaaga accggggcau uaucaagacc     1200

uucuccaaug ggugugauua uguuagcaac aaaggagugg acacagucuc cgugggcaau     1260

acccuuuacu auguuaacaa gcaagagggc aaaucucugu acgugaaggg ggaacccauc     1320

auuaacuuuu augacccucu cgucuucccc agcgaugagu uugacgccuc caucucucag     1380

gugaaugaga aaauuaacca gagccuggcu uucauccgca aguccgauga acugcuccac     1440

aaugugaacg ccggaaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucucu gaucgccgug ggccuccugc uguacugcaa agcuagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4586
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt6)

<400>  4586
gggagaaagc uuaccaugga auuacucauc cucaaagcaa acgcaauaac aacaauacua       60

acagcaguca cuuucugcuu cgcauccgga caaaauauca cagaagaauu uuaccaaucc      120

accugcucug cugucuccaa aggauaccua ucugcccuca gaaccgguug guauacaucu      180

gucauaacca uagaacuauc aaacauuaaa gaaaacaaau guaacggaac agacgcaaaa      240

gucaaacuua uaaaacaaga auuagacaaa uacaaaaacg cagucacaga auuacaacua      300

cuaaugcaau caaccccagc aaccggauca ggauccgcaa uagcuucagg aguagcagua      360

uguaaaguuc uacacuuaga aggagaaguc aacaaaauua aauccgcacu auuaucaacc      420

aacaaagcag ucguaucuuu aucaaacgga guaucuguac uuacauucaa aguacuagac      480

cuaaaaaauu acauugauaa acaauuacua ccaauacuaa acaaacaauc auguuccauc      540

ucuaacauag aaacaguaau agaauuucaa caaaaaaaua acagauuacu ugaaaucacc      600

cgagaauuuu caguaaacgc aggaguaacc acacccguau cuacauacau gcuaacaaac      660

ucugaacuuc ugagccuaau aaaugacaug ccaauaacca acgaccaaaa aaaacuaaug      720

uccaacaacg uacaaauagu acgacaacaa ucuuacucaa ucaugugcau aaucaaagaa      780

gaaguacuag cuuauguagu ccaacuucca cucuacggag uaauagacac ccccugcugg      840

aaacuacaca caucaccacu augcacaaca aacacaaaag aaggcucaaa cauaugccua      900

acaagaacug acagaggaug guauugugac aaugcaggcu cugucucauu cuuuccacaa      960

gccgaaacau gcaaaguuca aucaaaccga guuuucugug acacaaugaa cucuagaacu     1020

cucccaucag aagucaacuu augcaacguu gacauauuca acccaaaaua ugacuguaaa     1080

auaaugacuu ccaaaacuga uguaucaucc uccgucauaa caucccuagg agcuauugua     1140

ucauguuacg ggaaaaccaa augcacagcc ucaaacaaaa accgcgguau cauaaaaaca     1200

uuuucaaacg gaugugauua cguaagcaau aaaggaguag acaccguauc aguaggaaau     1260

acacuauacu auguaaauaa acaagaagga aaaucacuau augucaaagg agaaccaauc     1320

auaaauuucu augacccacu uguauuccca uccgaugaau uugacgcaag cauuucacag     1380

gucaacgaaa aaauaaacca aucacuagcc uucaucagaa aaucagacga acuacuacau     1440

aacguaaacg ccggaaaauc aacaaccaac auaaugauaa caacaaucau aauaguuauc     1500

auaguaauac uacuaucucu aauagcuguc ggacucuuac uauauugcaa agcccgauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4587
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut0 (opt11)

<400>  4587
gggagaaagc uuaccaugga acuacuaauc cugaaagcca acgccauaac cacaauccuu       60

accgcaguca ccuucugcuu cgccuccggu caaaacauca cagaagaguu cuaccaaucc      120

accuguuccg cagucagcaa aggcuaccuc uccgcacucc gaaccggaug guacaccagc      180

gucaucacca ucgaacuauc caacauaaag gaaaauaagu gcaaugguac agaugccaag      240

gucaaacuca uaaagcaaga acucgacaaa uacaaaaacg ccgucaccga acuacaacua      300

cuaaugcaau cuacccccgc aacaggcuca gguuccgcca uagccuccgg cgucgccguu      360

ugcaaagucc uccaccucga aggcgaagua aacaaaauca aauccgcccu acucucaacc      420

aacaaagcag ucgucucccu cucaaacgga gucucggucc ucaccuucaa aguccucgac      480

cucaaaaacu auauagacaa acaacuccua cccauacuca acaaacaguc cugcagcaua      540

uccaacaucg aaaccgugau cgaguuccaa cagaaaaaca acagacuccu cgaaaucacu      600

cgagaguucu ccguaaacgc cggcgucaca accccagucu caacauacau gcucaccaac      660

agcgaacucc uaucacuaau caacgacaug ccuaucacaa augaucagaa gaaacuaaug      720

agcaacaacg uccaaaucgu ccgccaacaa ucauacucca ucaugugcau cauaaaagaa      780

gaaguccuag ccuacguggu ccagcuaccc cucuacggcg uaauugacac cccuugcugg      840

aaacuacaca cuucaccccu cugcacaacc aacaccaaag aagguucaaa caucugccuc      900

acacgaacag accgcggcug guacugcgac aacgccggau ccguauccuu cuucccccaa      960

gcagaaaccu gcaaaguuca auccaaccgg guauucugcg acaccaugaa cucaagaacc     1020

cuucccuccg aaguaaaucu augcaacguc gacauauuca acccaaaaua cgacugcaaa     1080

aucaugaccu ccaaaaccga ugucuccagc agcgucauca ccagccucgg cgccaucguc     1140

uccugcuacg gcaaaacaaa auguacagca uccaacaaaa accgaggcau aaucaaaacc     1200

uucuccaacg ggugcgauua cgucagcaac aaaggcgucg acaccgucuc cgugggcaac     1260

acccuauacu acgucaacaa acaagaaggc aaaucacugu acguaaaggg cgaacccauc     1320

aucaacuucu augacccucu gguguuccca uccgaugaau uugacgcauc cauaucucag     1380

gucaacgaaa agaucaacca aucccucgcc uucauacgca aauccgacga acuccuacac     1440

aacgucaacg cugguaaaag caccaccaac aucaugauca ccacaaucau caucgucaua     1500

aucguuaucc uacucucccu uauagcaguc ggacuccucc ucuacugcaa agcccgcuaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  4588
<211>  535
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4588

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Ser 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Arg Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly Ile 
        515                 520                 525             


Asn Asn Ile Ala Phe Ser Asn 
    530                 535 


<210>  4589
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4589
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1560

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacuga                  1608


<210>  4590
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4590
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccaccg gcagcggguc cgccaucugc agcggcgugg ccgugugcaa gguccugcac      360

cucgagggcg aggugaacaa gaucaagucc gcgcugcuga gcaccaacaa ggccgugguc      420

ucccucagca acgggguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccccugua cggggugauc gacacgccgu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      900

gggugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1020

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1140

accaagugca ccgccagcaa caagaaccgg ggcaucauca agaccuucuc caacgggugc     1200

gacuacguga gcaacaaggg cgucgacacg gugagcgugg gcaacacccu cuacugcguc     1260

aacaagcagg aggggaaguc ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggg     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguccacccc ggugacccug     1560

agcaaggacc agcucuccgg gaucaacaac aucgccuuca gcaacuga                  1608


<210>  4591
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4591
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1560

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacuga                  1608


<210>  4592
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4592
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccaccg gcucgggguc agcuauaugu agcggagugg cagucugcaa gguguugcac      360

cucgagggcg aaguuaacaa aaucaagagu gcccugcugu ccacgaauaa agcugugguc      420

ucucucagca acgguguguc cguauuaacu uuuaagguuc uggaccuuaa gaauuacauu      480

gauaaacaau ugcugccuau ccuaaacaag cagucaugua guauuagcaa uaucgagacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuucuguc      600

aacgccgggg ugacuacccc aguguccaca uauaugcuua ccaauucaga acuguugagc      660

cucaucaacg acaugccgau uacgaacgau caaaagaaac ugaugaguaa uaacguccag      720

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcguau      780

guagugcaac ugccccucua cggagucauc gacacuccuu guuggaaacu ucauacaagc      840

ccacugugca ccacuaauac aaaggagggc ucgaacauuu guuugacccg aacggaucgu      900

ggcugguacu gcgacaaugc agggucugug uccuucuuuc cccaggccga aaccuguaag      960

guucagucaa acagaguguu cugcgauaca augaauagua gaacucugcc uagcgagguc     1020

aaccucugca auguggacau cuuuaaccca aaauaugauu guaagauaau gaccuccaaa     1080

acagacguau cuagcucagu uauuaccagu cugggagcua ucguguccug cuacgguaag     1140

acuaaaugua cagccagcaa uaagaacagg ggcaucauua agaccuucuc uaaugggugc     1200

gauuaugucu caaacaaagg aguggacacu gucagugugg gcaauacgcu uuacuguguu     1260

aacaagcaag aggguaaaag ccuguaugug aagggggaac ccaucauuaa cuuuuacgac     1320

ccuuugguau ucccauccga ugaguuugac gcaucuauau cgcaggucaa ugagaaaauc     1380

aaccagagcc ucgcuuucau ucggaagucc gaugaacugu uacacaaugu gaacgccgga     1440

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

agucucaucg cggucggccu gcuuuuguau ugcaaagccc gcucuacacc ggugacccug     1560

agcaaggacc agcucuccgg cauaaacaau aucgcauucu caaacuga                  1608


<210>  4593
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4593
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1560

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  4594
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4594
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacag ggucuggaag cgcuauuugu uccggcgucg ccgugugcaa gguucuccac      360

cuggaggggg aagugaacaa aaucaagagc gcgcuucugu cuaccaauaa agccgucgug      420

ucccucagca acggaguuuc ugugcugaca uuuaaggucc uugaccugaa gaauuacauu      480

gauaaacaac uccugccuau ccugaacaag caguccugua gcauuucuaa uaucgagacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuuccgug      600

aacgcuggcg ucacaacccc gguuagcaca uauaugcuua ccaauuccga acugcucucu      660

cugaucaacg acaugcccau uaccaacgau caaaagaaac uuaugagcaa uaacgugcag      720

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggccuau      780

gugguucaac ucccucugua cggcgugauc gacacacccu guuggaaacu gcauacgucu      840

ccucucugca ccacaaauac caaggagggg uccaacaucu gucugacacg gaccgaucgc      900

ggaugguacu gcgacaaugc uggcagcguc ucuuucuuuc cccaggccga aacguguaag      960

gugcagagca acagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1020

aaucucugca augucgacau uuuuaacccg aaauaugauu guaagaucau gaccagcaaa     1080

acagacgugu ccagcucugu cauuaccucc cugggggcga ucgugagcug cuacggaaag     1140

acaaaaugua cggccucuaa uaagaaccgg ggcauuauca agaccuucuc caaugggugc     1200

gauuauguua gcaacaaagg aguggacaca gucuccgugg gcaauacccu uuacuguguu     1260

aacaagcaag agggcaaauc ucuguaugug aagggggaac ccaucauuaa cuuuuacgac     1320

ccucucgucu uccccagcga ugaguuugac gcuuccaucu cucaggugaa ugagaaaauu     1380

aaccagagcc uggccuucau ccgcaagucc gaugaacugc uccacaaugu gaacgcugga     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucucugaucg ccgugggccu ccugcuguau ugcaaagcca gauccacacc ugugacccuu     1560

agcaaggacc agcucucugg gauuaacaau aucgcuuucu ccaacuga                  1608


<210>  4595
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4595
auggaacuuc uaauacucaa agccaacgca auaacaacaa uauuaacagc cguaacauuu       60

ugcuucgcau caggucaaaa cauaacagaa gaguucuacc aauccacaug cucagcagua      120

ucaaaaggau auuuaagugc ucuaagaaca ggaugguaca cauccguaau aacaaucgaa      180

cuaucaaaca uaaaagaaaa uaaauguaau ggaacagacg ccaaaguaaa auuaaucaaa      240

caagaacuag acaaauacaa aaacgcaguu acugaauuac aauuauuaau gcaaucaaca      300

ccggccacag gaucuggauc agcaauaugc ucaggaguag cagucugcaa aguauuacac      360

cuagaagggg aaguuaauaa aaucaaauca gcauuacuau ccaccaacaa agcgguaguu      420

ucacucucca acggcguauc ugucuuaaca uucaaaguau uagaccuaaa aaacuacauu      480

gacaaacaac uacuaccaau ccuaaacaaa caaucauguu ccauaagcaa uauagaaaca      540

guaauagaau uucaacaaaa aaacaacaga cuauuagaaa uaacaagaga auuuuccguc      600

aaugcaggag uuacuacccc ugucuccacc uauaugcuaa ccaauuccga acucuuauca      660

uuaauaaacg acaugccuau cacaaaugac caaaaaaaau uaaugagcaa caacguacaa      720

auaguacgac aacaaucaua cucaaucaug ugcauaauaa aagaagaagu ccuagcauac      780

guuguacaac uaccacuaua cggagucaua gauaccccau gcuggaaacu ccauacaagc      840

ccacuaugca cuacaaacac aaaagaaggc ucuaauauau gucuaacaag aacagaccga      900

ggaugguacu gcgauaaugc cggcucaguc ucauucuuuc cgcaagccga aacuuguaaa      960

guacaaagua acagaguauu uugugacacc augaacucaa gaacccuccc aagcgaaguc     1020

aaucuaugca acguugauau auucaauccc aaauacgacu gcaaaaucau gaccucaaaa     1080

acagacguca gcucauccgu uauaacauca cuaggagcca ucguaucuug cuauggaaaa     1140

acaaaaugca cagcaagcaa uaaaaacaga ggcauaauaa aaacauucuc aaauggaugc     1200

gacuacguau caaacaaagg agucgacaca guuuccguag gaaacacuuu auacugcgua     1260

aacaaacaag aaggaaaauc auuauacguc aaaggugaac caauaauaaa cuucuacgau     1320

ccacuuguau ucccaucaga cgaauuugac gcaucaauuu cacaaguaaa cgaaaaaaua     1380

aaccaaucac ucgcauucau aagaaaauca gaugaacuac uacauaacgu aaacgcagga     1440

aaauccacaa caaacaucau gauaacaacc aucauaaucg uaauaaucgu aauacuauua     1500

ucccuaauug caguaggauu acucuuauau ugcaaagcaa gaucaacacc aguaacccuc     1560

aguaaagacc aacuauccgg aauaaauaac aucgcauucu caaacuaa                  1608


<210>  4596
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut4

<400>  4596
auggaacugc ucauccucaa agccaacgcc aucaccacca uucuuaccgc cgucacauuc       60

ugcuucgccu caggccaaaa caucaccgaa gaauuuuacc aauccacuug uucagccguc      120

ucaaaaggau accuaucagc ccuccguacc ggcugguaca ccucggucau aacaauagaa      180

cucuccaaca uaaaagaaaa caaaugcaac ggcaccgacg ccaaggucaa acugauaaaa      240

caagaacuug auaaauacaa aaacgccguc acugaacucc aacuccucau gcaauccacu      300

cccgcuacug gcucuggcuc cgccaucugc ucuggcgucg ccgucuguaa aguacuccac      360

cucgaagggg aagucaacaa aaucaaauca gcccuccuua gcaccaacaa ggccgucguc      420

ucccucucaa acggagucag cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaaacaac uccugcccau ccuaaauaaa caauccugcu cuaucuccaa uaucgaaacc      540

guuauagagu uccaacagaa aaacaaccga cuccucgaaa ucacccgcga guucuccguc      600

aacgcaggcg ucaccacccc ugugucaacc uacaugcuca ccaacagcga acuacucuca      660

cucaucaaug acaugcccau caccaacgac caaaagaaac ucauguccaa caacguccaa      720

aucguacguc aacaauccua cagcaucaug ugcaucauaa aagaagaagu ccucgccuac      780

gucguccaac uuccccucua cggcgucaua gacacccccu gcuggaaacu gcauaccuca      840

ccccuaugca ccaccaacac uaaagaaggc uccaacaucu gccucacccg cacggaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaagccga aacuuguaaa      960

guccaaucca acagagucuu cugcgacacc augaacucua gaacgcugcc auccgaggua     1020

aaccuaugca acgucgacau cuucaauccc aaauacgacu gcaagaucau gaccucaaaa     1080

accgacguau ccuccucagu aaucaccagu cucggagcua ucgucuccug cuacggcaaa     1140

accaaaugca cggccucuaa caaaaaccgc ggcaucauca aaaccuucuc aaacggaugc     1200

gacuacguca gcaacaaagg cguagauacc gucucugucg gcaacacacu guacugcgua     1260

aacaagcaag aaggaaaauc ccucuacgua aaaggcgaac ccaucaucaa cuucuacgac     1320

ccccucguuu uccccucaga ugaauuugac gccucgauau cacaagucaa cgaaaagaua     1380

aaucaguccc ucgccuucau ccgaaaaucc gacgaacucc uccacaacgu uaacgcagga     1440

aaguccacca caaacaucau gauaacuaca aucauaauag ucauuaucgu cauacuccuc     1500

ucccuaaucg ccguaggccu gcuacucuac ugcaaagccc gcucaacccc cgucacucuc     1560

ucaaaagacc aacucuccgg caucaauaac aucgccuucu caaacuaa                  1608


<210>  4597
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4597
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4598
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4598
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4599
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4599
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4600
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4600
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcauucucaa     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4601
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4601
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4602
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4602
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcuuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4603
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4603
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uacucaaagc caacgcaaua acaacaauau      120

uaacagccgu aacauuuugc uucgcaucag gucaaaacau aacagaagag uucuaccaau      180

ccacaugcuc agcaguauca aaaggauauu uaagugcucu aagaacagga ugguacacau      240

ccguaauaac aaucgaacua ucaaacauaa aagaaaauaa auguaaugga acagacgcca      300

aaguaaaauu aaucaaacaa gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau      360

uauuaaugca aucaacaccg gccacaggau cuggaucagc aauaugcuca ggaguagcag      420

ucugcaaagu auuacaccua gaaggggaag uuaauaaaau caaaucagca uuacuaucca      480

ccaacaaagc gguaguuuca cucuccaacg gcguaucugu cuuaacauuc aaaguauuag      540

accuaaaaaa cuacauugac aaacaacuac uaccaauccu aaacaaacaa ucauguucca      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua uuagaaauaa      660

caagagaauu uuccgucaau gcaggaguua cuaccccugu cuccaccuau augcuaacca      720

auuccgaacu cuuaucauua auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa      780

ugagcaacaa cguacaaaua guacgacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguccu agcauacguu guacaacuac cacuauacgg agucauagau accccaugcu      900

ggaaacucca uacaagccca cuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacaagaac agaccgagga ugguacugcg auaaugccgg cucagucuca uucuuuccgc     1020

aagccgaaac uuguaaagua caaaguaaca gaguauuuug ugacaccaug aacucaagaa     1080

cccucccaag cgaagucaau cuaugcaacg uugauauauu caaucccaaa uacgacugca     1140

aaaucaugac cucaaaaaca gacgucagcu cauccguuau aacaucacua ggagccaucg     1200

uaucuugcua uggaaaaaca aaaugcacag caagcaauaa aaacagaggc auaauaaaaa     1260

cauucucaaa uggaugcgac uacguaucaa acaaaggagu cgacacaguu uccguaggaa     1320

acacuuuaua cugcguaaac aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa     1380

uaauaaacuu cuacgaucca cuuguauucc caucagacga auuugacgca ucaauuucac     1440

aaguaaacga aaaaauaaac caaucacucg cauucauaag aaaaucagau gaacuacuac     1500

auaacguaaa cgcaggaaaa uccacaacaa acaucaugau aacaaccauc auaaucguaa     1560

uaaucguaau acuauuaucc cuaauugcag uaggauuacu cuuauauugc aaagcaagau     1620

caacaccagu aacccucagu aaagaccaac uauccggaau aaauaacauc gcauucucaa     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4604
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4604
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacugcuca uccucaaagc caacgccauc accaccauuc      120

uuaccgccgu cacauucugc uucgccucag gccaaaacau caccgaagaa uuuuaccaau      180

ccacuuguuc agccgucuca aaaggauacc uaucagcccu ccguaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaacauaa aagaaaacaa augcaacggc accgacgcca      300

aggucaaacu gauaaaacaa gaacuugaua aauacaaaaa cgccgucacu gaacuccaac      360

uccucaugca auccacuccc gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg      420

ucuguaaagu acuccaccuc gaaggggaag ucaacaaaau caaaucagcc cuccuuagca      480

ccaacaaggc cgucgucucc cucucaaacg gagucagcgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aaacaacucc ugcccauccu aaauaaacaa uccugcucua      600

ucuccaauau cgaaaccguu auagaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gcaggcguca ccaccccugu gucaaccuac augcucacca      720

acagcgaacu acucucacuc aucaaugaca ugcccaucac caacgaccaa aagaaacuca      780

uguccaacaa cguccaaauc guacgucaac aauccuacag caucaugugc aucauaaaag      840

aagaaguccu cgccuacguc guccaacuuc cccucuacgg cgucauagac acccccugcu      900

ggaaacugca uaccucaccc cuaugcacca ccaacacuaa agaaggcucc aacaucugcc      960

ucacccgcac ggaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac uuguaaaguc caauccaaca gagucuucug cgacaccaug aacucuagaa     1080

cgcugccauc cgagguaaac cuaugcaacg ucgacaucuu caaucccaaa uacgacugca     1140

agaucaugac cucaaaaacc gacguauccu ccucaguaau caccagucuc ggagcuaucg     1200

ucuccugcua cggcaaaacc aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa     1260

ccuucucaaa cggaugcgac uacgucagca acaaaggcgu agauaccguc ucugucggca     1320

acacacugua cugcguaaac aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucguuuucc ccucagauga auuugacgcc ucgauaucac     1440

aagucaacga aaagauaaau cagucccucg ccuucauccg aaaauccgac gaacuccucc     1500

acaacguuaa cgcaggaaag uccaccacaa acaucaugau aacuacaauc auaauaguca     1560

uuaucgucau acuccucucc cuaaucgccg uaggccugcu acucuacugc aaagcccgcu     1620

caacccccgu cacucucuca aaagaccaac ucuccggcau caauaacauc gccuucucaa     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  4605
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4605
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4606
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4606
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4607
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4607
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4608
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4608
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cauucucaaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4609
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4609
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4610
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4610
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cuuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4611
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4611
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau acucaaagcc      120

aacgcaauaa caacaauauu aacagccgua acauuuugcu ucgcaucagg ucaaaacaua      180

acagaagagu ucuaccaauc cacaugcuca gcaguaucaa aaggauauuu aagugcucua      240

agaacaggau gguacacauc cguaauaaca aucgaacuau caaacauaaa agaaaauaaa      300

uguaauggaa cagacgccaa aguaaaauua aucaaacaag aacuagacaa auacaaaaac      360

gcaguuacug aauuacaauu auuaaugcaa ucaacaccgg ccacaggauc uggaucagca      420

auaugcucag gaguagcagu cugcaaagua uuacaccuag aaggggaagu uaauaaaauc      480

aaaucagcau uacuauccac caacaaagcg guaguuucac ucuccaacgg cguaucuguc      540

uuaacauuca aaguauuaga ccuaaaaaac uacauugaca aacaacuacu accaauccua      600

aacaaacaau cauguuccau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuau uagaaauaac aagagaauuu uccgucaaug caggaguuac uaccccuguc      720

uccaccuaua ugcuaaccaa uuccgaacuc uuaucauuaa uaaacgacau gccuaucaca      780

aaugaccaaa aaaaauuaau gagcaacaac guacaaauag uacgacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguccua gcauacguug uacaacuacc acuauacgga      900

gucauagaua ccccaugcug gaaacuccau acaagcccac uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacaagaaca gaccgaggau gguacugcga uaaugccggc     1020

ucagucucau ucuuuccgca agccgaaacu uguaaaguac aaaguaacag aguauuuugu     1080

gacaccauga acucaagaac ccucccaagc gaagucaauc uaugcaacgu ugauauauuc     1140

aaucccaaau acgacugcaa aaucaugacc ucaaaaacag acgucagcuc auccguuaua     1200

acaucacuag gagccaucgu aucuugcuau ggaaaaacaa aaugcacagc aagcaauaaa     1260

aacagaggca uaauaaaaac auucucaaau ggaugcgacu acguaucaaa caaaggaguc     1320

gacacaguuu ccguaggaaa cacuuuauac ugcguaaaca aacaagaagg aaaaucauua     1380

uacgucaaag gugaaccaau aauaaacuuc uacgauccac uuguauuccc aucagacgaa     1440

uuugacgcau caauuucaca aguaaacgaa aaaauaaacc aaucacucgc auucauaaga     1500

aaaucagaug aacuacuaca uaacguaaac gcaggaaaau ccacaacaaa caucaugaua     1560

acaaccauca uaaucguaau aaucguaaua cuauuauccc uaauugcagu aggauuacuc     1620

uuauauugca aagcaagauc aacaccagua acccucagua aagaccaacu auccggaaua     1680

aauaacaucg cauucucaaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4612
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4612
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacugcucau ccucaaagcc      120

aacgccauca ccaccauucu uaccgccguc acauucugcu ucgccucagg ccaaaacauc      180

accgaagaau uuuaccaauc cacuuguuca gccgucucaa aaggauaccu aucagcccuc      240

cguaccggcu gguacaccuc ggucauaaca auagaacucu ccaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa ggucaaacug auaaaacaag aacuugauaa auacaaaaac      360

gccgucacug aacuccaacu ccucaugcaa uccacucccg cuacuggcuc uggcuccgcc      420

aucugcucug gcgucgccgu cuguaaagua cuccaccucg aaggggaagu caacaaaauc      480

aaaucagccc uccuuagcac caacaaggcc gucgucuccc ucucaaacgg agucagcguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca aacaacuccu gcccauccua      600

aauaaacaau ccugcucuau cuccaauauc gaaaccguua uagaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg caggcgucac caccccugug      720

ucaaccuaca ugcucaccaa cagcgaacua cucucacuca ucaaugacau gcccaucacc      780

aacgaccaaa agaaacucau guccaacaac guccaaaucg uacgucaaca auccuacagc      840

aucaugugca ucauaaaaga agaaguccuc gccuacgucg uccaacuucc ccucuacggc      900

gucauagaca cccccugcug gaaacugcau accucacccc uaugcaccac caacacuaaa      960

gaaggcucca acaucugccu cacccgcacg gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacu uguaaagucc aauccaacag agucuucugc     1080

gacaccauga acucuagaac gcugccaucc gagguaaacc uaugcaacgu cgacaucuuc     1140

aaucccaaau acgacugcaa gaucaugacc ucaaaaaccg acguauccuc cucaguaauc     1200

accagucucg gagcuaucgu cuccugcuac ggcaaaacca aaugcacggc cucuaacaaa     1260

aaccgcggca ucaucaaaac cuucucaaac ggaugcgacu acgucagcaa caaaggcgua     1320

gauaccgucu cugucggcaa cacacuguac ugcguaaaca agcaagaagg aaaaucccuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucguuuuccc cucagaugaa     1440

uuugacgccu cgauaucaca agucaacgaa aagauaaauc agucccucgc cuucauccga     1500

aaauccgacg aacuccucca caacguuaac gcaggaaagu ccaccacaaa caucaugaua     1560

acuacaauca uaauagucau uaucgucaua cuccucuccc uaaucgccgu aggccugcua     1620

cucuacugca aagcccgcuc aacccccguc acucucucaa aagaccaacu cuccggcauc     1680

aauaacaucg ccuucucaaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  4613
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4613
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4614
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4614
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4615
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4615
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4616
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4616
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgca uucucaaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4617
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4617
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4618
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4618
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcu uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4619
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4619
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauac ucaaagccaa cgcaauaaca acaauauuaa cagccguaac auuuugcuuc      240

gcaucagguc aaaacauaac agaagaguuc uaccaaucca caugcucagc aguaucaaaa      300

ggauauuuaa gugcucuaag aacaggaugg uacacauccg uaauaacaau cgaacuauca      360

aacauaaaag aaaauaaaug uaauggaaca gacgccaaag uaaaauuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguuacugaa uuacaauuau uaaugcaauc aacaccggcc      480

acaggaucug gaucagcaau augcucagga guagcagucu gcaaaguauu acaccuagaa      540

ggggaaguua auaaaaucaa aucagcauua cuauccacca acaaagcggu aguuucacuc      600

uccaacggcg uaucugucuu aacauucaaa guauuagacc uaaaaaacua cauugacaaa      660

caacuacuac caauccuaaa caaacaauca uguuccauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuauua gaaauaacaa gagaauuuuc cgucaaugca      780

ggaguuacua ccccugucuc caccuauaug cuaaccaauu ccgaacucuu aucauuaaua      840

aacgacaugc cuaucacaaa ugaccaaaaa aaauuaauga gcaacaacgu acaaauagua      900

cgacaacaau cauacucaau caugugcaua auaaaagaag aaguccuagc auacguugua      960

caacuaccac uauacggagu cauagauacc ccaugcugga aacuccauac aagcccacua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa caagaacaga ccgaggaugg     1080

uacugcgaua augccggcuc agucucauuc uuuccgcaag ccgaaacuug uaaaguacaa     1140

aguaacagag uauuuuguga caccaugaac ucaagaaccc ucccaagcga agucaaucua     1200

ugcaacguug auauauucaa ucccaaauac gacugcaaaa ucaugaccuc aaaaacagac     1260

gucagcucau ccguuauaac aucacuagga gccaucguau cuugcuaugg aaaaacaaaa     1320

ugcacagcaa gcaauaaaaa cagaggcaua auaaaaacau ucucaaaugg augcgacuac     1380

guaucaaaca aaggagucga cacaguuucc guaggaaaca cuuuauacug cguaaacaaa     1440

caagaaggaa aaucauuaua cgucaaaggu gaaccaauaa uaaacuucua cgauccacuu     1500

guauucccau cagacgaauu ugacgcauca auuucacaag uaaacgaaaa aauaaaccaa     1560

ucacucgcau ucauaagaaa aucagaugaa cuacuacaua acguaaacgc aggaaaaucc     1620

acaacaaaca ucaugauaac aaccaucaua aucguaauaa ucguaauacu auuaucccua     1680

auugcaguag gauuacucuu auauugcaaa gcaagaucaa caccaguaac ccucaguaaa     1740

gaccaacuau ccggaauaaa uaacaucgca uucucaaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4620
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4620
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cugcucaucc ucaaagccaa cgccaucacc accauucuua ccgccgucac auucugcuuc      240

gccucaggcc aaaacaucac cgaagaauuu uaccaaucca cuuguucagc cgucucaaaa      300

ggauaccuau cagcccuccg uaccggcugg uacaccucgg ucauaacaau agaacucucc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaagg ucaaacugau aaaacaagaa      420

cuugauaaau acaaaaacgc cgucacugaa cuccaacucc ucaugcaauc cacucccgcu      480

acuggcucug gcuccgccau cugcucuggc gucgccgucu guaaaguacu ccaccucgaa      540

ggggaaguca acaaaaucaa aucagcccuc cuuagcacca acaaggccgu cgucucccuc      600

ucaaacggag ucagcguccu caccuucaag guccucgacc ucaagaacua caucgacaaa      660

caacuccugc ccauccuaaa uaaacaaucc ugcucuaucu ccaauaucga aaccguuaua      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgca      780

ggcgucacca ccccuguguc aaccuacaug cucaccaaca gcgaacuacu cucacucauc      840

aaugacaugc ccaucaccaa cgaccaaaag aaacucaugu ccaacaacgu ccaaaucgua      900

cgucaacaau ccuacagcau caugugcauc auaaaagaag aaguccucgc cuacgucguc      960

caacuucccc ucuacggcgu cauagacacc cccugcugga aacugcauac cucaccccua     1020

ugcaccacca acacuaaaga aggcuccaac aucugccuca cccgcacgga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaacuug uaaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucuagaacgc ugccauccga gguaaaccua     1200

ugcaacgucg acaucuucaa ucccaaauac gacugcaaga ucaugaccuc aaaaaccgac     1260

guauccuccu caguaaucac cagucucgga gcuaucgucu ccugcuacgg caaaaccaaa     1320

ugcacggccu cuaacaaaaa ccgcggcauc aucaaaaccu ucucaaacgg augcgacuac     1380

gucagcaaca aaggcguaga uaccgucucu gucggcaaca cacuguacug cguaaacaag     1440

caagaaggaa aaucccucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

guuuuccccu cagaugaauu ugacgccucg auaucacaag ucaacgaaaa gauaaaucag     1560

ucccucgccu ucauccgaaa auccgacgaa cuccuccaca acguuaacgc aggaaagucc     1620

accacaaaca ucaugauaac uacaaucaua auagucauua ucgucauacu ccucucccua     1680

aucgccguag gccugcuacu cuacugcaaa gcccgcucaa cccccgucac ucucucaaaa     1740

gaccaacucu ccggcaucaa uaacaucgcc uucucaaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  4621
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4621
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4622
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4622
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4623
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4623
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4624
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4624
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcau ucucaaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4625
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4625
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4626
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4626
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcuu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4627
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4627
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauacu caaagccaac gcaauaacaa caauauuaac agccguaaca      180

uuuugcuucg caucagguca aaacauaaca gaagaguucu accaauccac augcucagca      240

guaucaaaag gauauuuaag ugcucuaaga acaggauggu acacauccgu aauaacaauc      300

gaacuaucaa acauaaaaga aaauaaaugu aauggaacag acgccaaagu aaaauuaauc      360

aaacaagaac uagacaaaua caaaaacgca guuacugaau uacaauuauu aaugcaauca      420

acaccggcca caggaucugg aucagcaaua ugcucaggag uagcagucug caaaguauua      480

caccuagaag gggaaguuaa uaaaaucaaa ucagcauuac uauccaccaa caaagcggua      540

guuucacucu ccaacggcgu aucugucuua acauucaaag uauuagaccu aaaaaacuac      600

auugacaaac aacuacuacc aauccuaaac aaacaaucau guuccauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuauuag aaauaacaag agaauuuucc      720

gucaaugcag gaguuacuac cccugucucc accuauaugc uaaccaauuc cgaacucuua      780

ucauuaauaa acgacaugcc uaucacaaau gaccaaaaaa aauuaaugag caacaacgua      840

caaauaguac gacaacaauc auacucaauc augugcauaa uaaaagaaga aguccuagca      900

uacguuguac aacuaccacu auacggaguc auagauaccc caugcuggaa acuccauaca      960

agcccacuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac aagaacagac     1020

cgaggauggu acugcgauaa ugccggcuca gucucauucu uuccgcaagc cgaaacuugu     1080

aaaguacaaa guaacagagu auuuugugac accaugaacu caagaacccu cccaagcgaa     1140

gucaaucuau gcaacguuga uauauucaau cccaaauacg acugcaaaau caugaccuca     1200

aaaacagacg ucagcucauc cguuauaaca ucacuaggag ccaucguauc uugcuaugga     1260

aaaacaaaau gcacagcaag caauaaaaac agaggcauaa uaaaaacauu cucaaaugga     1320

ugcgacuacg uaucaaacaa aggagucgac acaguuuccg uaggaaacac uuuauacugc     1380

guaaacaaac aagaaggaaa aucauuauac gucaaaggug aaccaauaau aaacuucuac     1440

gauccacuug uauucccauc agacgaauuu gacgcaucaa uuucacaagu aaacgaaaaa     1500

auaaaccaau cacucgcauu cauaagaaaa ucagaugaac uacuacauaa cguaaacgca     1560

ggaaaaucca caacaaacau caugauaaca accaucauaa ucguaauaau cguaauacua     1620

uuaucccuaa uugcaguagg auuacucuua uauugcaaag caagaucaac accaguaacc     1680

cucaguaaag accaacuauc cggaauaaau aacaucgcau ucucaaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4628
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4628
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac ugcucauccu caaagccaac gccaucacca ccauucuuac cgccgucaca      180

uucugcuucg ccucaggcca aaacaucacc gaagaauuuu accaauccac uuguucagcc      240

gucucaaaag gauaccuauc agcccuccgu accggcuggu acaccucggu cauaacaaua      300

gaacucucca acauaaaaga aaacaaaugc aacggcaccg acgccaaggu caaacugaua      360

aaacaagaac uugauaaaua caaaaacgcc gucacugaac uccaacuccu caugcaaucc      420

acucccgcua cuggcucugg cuccgccauc ugcucuggcg ucgccgucug uaaaguacuc      480

caccucgaag gggaagucaa caaaaucaaa ucagcccucc uuagcaccaa caaggccguc      540

gucucccucu caaacggagu cagcguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaaac aacuccugcc cauccuaaau aaacaauccu gcucuaucuc caauaucgaa      660

accguuauag aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgcag gcgucaccac cccuguguca accuacaugc ucaccaacag cgaacuacuc      780

ucacucauca augacaugcc caucaccaac gaccaaaaga aacucauguc caacaacguc      840

caaaucguac gucaacaauc cuacagcauc augugcauca uaaaagaaga aguccucgcc      900

uacgucgucc aacuuccccu cuacggcguc auagacaccc ccugcuggaa acugcauacc      960

ucaccccuau gcaccaccaa cacuaaagaa ggcuccaaca ucugccucac ccgcacggac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaacuugu     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cuagaacgcu gccauccgag     1140

guaaaccuau gcaacgucga caucuucaau cccaaauacg acugcaagau caugaccuca     1200

aaaaccgacg uauccuccuc aguaaucacc agucucggag cuaucgucuc cugcuacggc     1260

aaaaccaaau gcacggccuc uaacaaaaac cgcggcauca ucaaaaccuu cucaaacgga     1320

ugcgacuacg ucagcaacaa aggcguagau accgucucug ucggcaacac acuguacugc     1380

guaaacaagc aagaaggaaa aucccucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg uuuuccccuc agaugaauuu gacgccucga uaucacaagu caacgaaaag     1500

auaaaucagu cccucgccuu cauccgaaaa uccgacgaac uccuccacaa cguuaacgca     1560

ggaaagucca ccacaaacau caugauaacu acaaucauaa uagucauuau cgucauacuc     1620

cucucccuaa ucgccguagg ccugcuacuc uacugcaaag cccgcucaac ccccgucacu     1680

cucucaaaag accaacucuc cggcaucaau aacaucgccu ucucaaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  4629
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4629
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4630
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4630
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4631
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4631
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4632
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4632
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcauucuc aaacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4633
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4633
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4634
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4634
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcuuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4635
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4635
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauacucaaa gccaacgcaa uaacaacaau auuaacagcc      120

guaacauuuu gcuucgcauc aggucaaaac auaacagaag aguucuacca auccacaugc      180

ucagcaguau caaaaggaua uuuaagugcu cuaagaacag gaugguacac auccguaaua      240

acaaucgaac uaucaaacau aaaagaaaau aaauguaaug gaacagacgc caaaguaaaa      300

uuaaucaaac aagaacuaga caaauacaaa aacgcaguua cugaauuaca auuauuaaug      360

caaucaacac cggccacagg aucuggauca gcaauaugcu caggaguagc agucugcaaa      420

guauuacacc uagaagggga aguuaauaaa aucaaaucag cauuacuauc caccaacaaa      480

gcgguaguuu cacucuccaa cggcguaucu gucuuaacau ucaaaguauu agaccuaaaa      540

aacuacauug acaaacaacu acuaccaauc cuaaacaaac aaucauguuc cauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uauuagaaau aacaagagaa      660

uuuuccguca augcaggagu uacuaccccu gucuccaccu auaugcuaac caauuccgaa      720

cucuuaucau uaauaaacga caugccuauc acaaaugacc aaaaaaaauu aaugagcaac      780

aacguacaaa uaguacgaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguc      840

cuagcauacg uuguacaacu accacuauac ggagucauag auaccccaug cuggaaacuc      900

cauacaagcc cacuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacaaga      960

acagaccgag gaugguacug cgauaaugcc ggcucagucu cauucuuucc gcaagccgaa     1020

acuuguaaag uacaaaguaa cagaguauuu ugugacacca ugaacucaag aacccuccca     1080

agcgaaguca aucuaugcaa cguugauaua uucaauccca aauacgacug caaaaucaug     1140

accucaaaaa cagacgucag cucauccguu auaacaucac uaggagccau cguaucuugc     1200

uauggaaaaa caaaaugcac agcaagcaau aaaaacagag gcauaauaaa aacauucuca     1260

aauggaugcg acuacguauc aaacaaagga gucgacacag uuuccguagg aaacacuuua     1320

uacugcguaa acaaacaaga aggaaaauca uuauacguca aaggugaacc aauaauaaac     1380

uucuacgauc cacuuguauu cccaucagac gaauuugacg caucaauuuc acaaguaaac     1440

gaaaaaauaa accaaucacu cgcauucaua agaaaaucag augaacuacu acauaacgua     1500

aacgcaggaa aauccacaac aaacaucaug auaacaacca ucauaaucgu aauaaucgua     1560

auacuauuau cccuaauugc aguaggauua cucuuauauu gcaaagcaag aucaacacca     1620

guaacccuca guaaagacca acuauccgga auaaauaaca ucgcauucuc aaacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4636
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4636
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacugcu cauccucaaa gccaacgcca ucaccaccau ucuuaccgcc      120

gucacauucu gcuucgccuc aggccaaaac aucaccgaag aauuuuacca auccacuugu      180

ucagccgucu caaaaggaua ccuaucagcc cuccguaccg gcugguacac cucggucaua      240

acaauagaac ucuccaacau aaaagaaaac aaaugcaacg gcaccgacgc caaggucaaa      300

cugauaaaac aagaacuuga uaaauacaaa aacgccguca cugaacucca acuccucaug      360

caauccacuc ccgcuacugg cucuggcucc gccaucugcu cuggcgucgc cgucuguaaa      420

guacuccacc ucgaagggga agucaacaaa aucaaaucag cccuccuuag caccaacaag      480

gccgucgucu cccucucaaa cggagucagc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaaacaacu ccugcccauc cuaaauaaac aauccugcuc uaucuccaau      600

aucgaaaccg uuauagaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgcaggcgu caccaccccu gugucaaccu acaugcucac caacagcgaa      720

cuacucucac ucaucaauga caugcccauc accaacgacc aaaagaaacu cauguccaac      780

aacguccaaa ucguacguca acaauccuac agcaucaugu gcaucauaaa agaagaaguc      840

cucgccuacg ucguccaacu uccccucuac ggcgucauag acacccccug cuggaaacug      900

cauaccucac cccuaugcac caccaacacu aaagaaggcu ccaacaucug ccucacccgc      960

acggaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

acuuguaaag uccaauccaa cagagucuuc ugcgacacca ugaacucuag aacgcugcca     1080

uccgagguaa accuaugcaa cgucgacauc uucaauccca aauacgacug caagaucaug     1140

accucaaaaa ccgacguauc cuccucagua aucaccaguc ucggagcuau cgucuccugc     1200

uacggcaaaa ccaaaugcac ggccucuaac aaaaaccgcg gcaucaucaa aaccuucuca     1260

aacggaugcg acuacgucag caacaaaggc guagauaccg ucucugucgg caacacacug     1320

uacugcguaa acaagcaaga aggaaaaucc cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucguuuu ccccucagau gaauuugacg ccucgauauc acaagucaac     1440

gaaaagauaa aucagucccu cgccuucauc cgaaaauccg acgaacuccu ccacaacguu     1500

aacgcaggaa aguccaccac aaacaucaug auaacuacaa ucauaauagu cauuaucguc     1560

auacuccucu cccuaaucgc cguaggccug cuacucuacu gcaaagcccg cucaaccccc     1620

gucacucucu caaaagacca acucuccggc aucaauaaca ucgccuucuc aaacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  4637
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4637
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1800

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4638
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4638
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      660

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1260

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1380

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1440

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1500

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1800

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4639
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4639
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1800

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4640
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4640
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      600

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      660

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      720

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      840

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      900

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      960

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua     1020

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca     1080

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc     1140

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1200

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1260

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1320

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1380

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1440

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1500

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1560

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1620

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1680

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1740

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu cuacaccggu gacccugagc     1800

aaggaccagc ucuccggcau aaacaauauc gcauucucaa acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4641
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4641
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1800

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4642
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4642
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      600

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      660

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      720

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      840

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      900

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      960

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug     1020

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu     1080

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga     1140

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1200

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1260

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1320

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1380

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1440

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1500

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1560

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1620

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1740

cugaucgccg ugggccuccu gcuguauugc aaagccagau ccacaccugu gacccuuagc     1800

aaggaccagc ucucugggau uaacaauauc gcuuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4643
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4643
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuucuaa uacucaaagc caacgcaaua acaacaauau uaacagccgu aacauuuugc      300

uucgcaucag gucaaaacau aacagaagag uucuaccaau ccacaugcuc agcaguauca      360

aaaggauauu uaagugcucu aagaacagga ugguacacau ccguaauaac aaucgaacua      420

ucaaacauaa aagaaaauaa auguaaugga acagacgcca aaguaaaauu aaucaaacaa      480

gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau uauuaaugca aucaacaccg      540

gccacaggau cuggaucagc aauaugcuca ggaguagcag ucugcaaagu auuacaccua      600

gaaggggaag uuaauaaaau caaaucagca uuacuaucca ccaacaaagc gguaguuuca      660

cucuccaacg gcguaucugu cuuaacauuc aaaguauuag accuaaaaaa cuacauugac      720

aaacaacuac uaccaauccu aaacaaacaa ucauguucca uaagcaauau agaaacagua      780

auagaauuuc aacaaaaaaa caacagacua uuagaaauaa caagagaauu uuccgucaau      840

gcaggaguua cuaccccugu cuccaccuau augcuaacca auuccgaacu cuuaucauua      900

auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa ugagcaacaa cguacaaaua      960

guacgacaac aaucauacuc aaucaugugc auaauaaaag aagaaguccu agcauacguu     1020

guacaacuac cacuauacgg agucauagau accccaugcu ggaaacucca uacaagccca     1080

cuaugcacua caaacacaaa agaaggcucu aauauauguc uaacaagaac agaccgagga     1140

ugguacugcg auaaugccgg cucagucuca uucuuuccgc aagccgaaac uuguaaagua     1200

caaaguaaca gaguauuuug ugacaccaug aacucaagaa cccucccaag cgaagucaau     1260

cuaugcaacg uugauauauu caaucccaaa uacgacugca aaaucaugac cucaaaaaca     1320

gacgucagcu cauccguuau aacaucacua ggagccaucg uaucuugcua uggaaaaaca     1380

aaaugcacag caagcaauaa aaacagaggc auaauaaaaa cauucucaaa uggaugcgac     1440

uacguaucaa acaaaggagu cgacacaguu uccguaggaa acacuuuaua cugcguaaac     1500

aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa uaauaaacuu cuacgaucca     1560

cuuguauucc caucagacga auuugacgca ucaauuucac aaguaaacga aaaaauaaac     1620

caaucacucg cauucauaag aaaaucagau gaacuacuac auaacguaaa cgcaggaaaa     1680

uccacaacaa acaucaugau aacaaccauc auaaucguaa uaaucguaau acuauuaucc     1740

cuaauugcag uaggauuacu cuuauauugc aaagcaagau caacaccagu aacccucagu     1800

aaagaccaac uauccggaau aaauaacauc gcauucucaa acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4644
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4644
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacugcuca uccucaaagc caacgccauc accaccauuc uuaccgccgu cacauucugc      300

uucgccucag gccaaaacau caccgaagaa uuuuaccaau ccacuuguuc agccgucuca      360

aaaggauacc uaucagcccu ccguaccggc ugguacaccu cggucauaac aauagaacuc      420

uccaacauaa aagaaaacaa augcaacggc accgacgcca aggucaaacu gauaaaacaa      480

gaacuugaua aauacaaaaa cgccgucacu gaacuccaac uccucaugca auccacuccc      540

gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg ucuguaaagu acuccaccuc      600

gaaggggaag ucaacaaaau caaaucagcc cuccuuagca ccaacaaggc cgucgucucc      660

cucucaaacg gagucagcgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aaacaacucc ugcccauccu aaauaaacaa uccugcucua ucuccaauau cgaaaccguu      780

auagaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      840

gcaggcguca ccaccccugu gucaaccuac augcucacca acagcgaacu acucucacuc      900

aucaaugaca ugcccaucac caacgaccaa aagaaacuca uguccaacaa cguccaaauc      960

guacgucaac aauccuacag caucaugugc aucauaaaag aagaaguccu cgccuacguc     1020

guccaacuuc cccucuacgg cgucauagac acccccugcu ggaaacugca uaccucaccc     1080

cuaugcacca ccaacacuaa agaaggcucc aacaucugcc ucacccgcac ggaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac uuguaaaguc     1200

caauccaaca gagucuucug cgacaccaug aacucuagaa cgcugccauc cgagguaaac     1260

cuaugcaacg ucgacaucuu caaucccaaa uacgacugca agaucaugac cucaaaaacc     1320

gacguauccu ccucaguaau caccagucuc ggagcuaucg ucuccugcua cggcaaaacc     1380

aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa ccuucucaaa cggaugcgac     1440

uacgucagca acaaaggcgu agauaccguc ucugucggca acacacugua cugcguaaac     1500

aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1560

cucguuuucc ccucagauga auuugacgcc ucgauaucac aagucaacga aaagauaaau     1620

cagucccucg ccuucauccg aaaauccgac gaacuccucc acaacguuaa cgcaggaaag     1680

uccaccacaa acaucaugau aacuacaauc auaauaguca uuaucgucau acuccucucc     1740

cuaaucgccg uaggccugcu acucuacugc aaagcccgcu caacccccgu cacucucuca     1800

aaagaccaac ucuccggcau caauaacauc gccuucucaa acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4645
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4645
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4646
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4646
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1620

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4647
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4647
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4648
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4648
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca      900

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc      960

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1020

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1200

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1320

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu cuacaccggu gacccugagc     1620

aaggaccagc ucuccggcau aaacaauauc gcauucucaa acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4649
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4649
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4650
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4650
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu      900

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga      960

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1200

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguauugc aaagccagau ccacaccugu gacccuuagc     1620

aaggaccagc ucucugggau uaacaauauc gcuuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4651
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4651
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuucuaa uacucaaagc caacgcaaua acaacaauau uaacagccgu aacauuuugc      120

uucgcaucag gucaaaacau aacagaagag uucuaccaau ccacaugcuc agcaguauca      180

aaaggauauu uaagugcucu aagaacagga ugguacacau ccguaauaac aaucgaacua      240

ucaaacauaa aagaaaauaa auguaaugga acagacgcca aaguaaaauu aaucaaacaa      300

gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau uauuaaugca aucaacaccg      360

gccacaggau cuggaucagc aauaugcuca ggaguagcag ucugcaaagu auuacaccua      420

gaaggggaag uuaauaaaau caaaucagca uuacuaucca ccaacaaagc gguaguuuca      480

cucuccaacg gcguaucugu cuuaacauuc aaaguauuag accuaaaaaa cuacauugac      540

aaacaacuac uaccaauccu aaacaaacaa ucauguucca uaagcaauau agaaacagua      600

auagaauuuc aacaaaaaaa caacagacua uuagaaauaa caagagaauu uuccgucaau      660

gcaggaguua cuaccccugu cuccaccuau augcuaacca auuccgaacu cuuaucauua      720

auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa ugagcaacaa cguacaaaua      780

guacgacaac aaucauacuc aaucaugugc auaauaaaag aagaaguccu agcauacguu      840

guacaacuac cacuauacgg agucauagau accccaugcu ggaaacucca uacaagccca      900

cuaugcacua caaacacaaa agaaggcucu aauauauguc uaacaagaac agaccgagga      960

ugguacugcg auaaugccgg cucagucuca uucuuuccgc aagccgaaac uuguaaagua     1020

caaaguaaca gaguauuuug ugacaccaug aacucaagaa cccucccaag cgaagucaau     1080

cuaugcaacg uugauauauu caaucccaaa uacgacugca aaaucaugac cucaaaaaca     1140

gacgucagcu cauccguuau aacaucacua ggagccaucg uaucuugcua uggaaaaaca     1200

aaaugcacag caagcaauaa aaacagaggc auaauaaaaa cauucucaaa uggaugcgac     1260

uacguaucaa acaaaggagu cgacacaguu uccguaggaa acacuuuaua cugcguaaac     1320

aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa uaauaaacuu cuacgaucca     1380

cuuguauucc caucagacga auuugacgca ucaauuucac aaguaaacga aaaaauaaac     1440

caaucacucg cauucauaag aaaaucagau gaacuacuac auaacguaaa cgcaggaaaa     1500

uccacaacaa acaucaugau aacaaccauc auaaucguaa uaaucguaau acuauuaucc     1560

cuaauugcag uaggauuacu cuuauauugc aaagcaagau caacaccagu aacccucagu     1620

aaagaccaac uauccggaau aaauaacauc gcauucucaa acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4652
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4652
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacugcuca uccucaaagc caacgccauc accaccauuc uuaccgccgu cacauucugc      120

uucgccucag gccaaaacau caccgaagaa uuuuaccaau ccacuuguuc agccgucuca      180

aaaggauacc uaucagcccu ccguaccggc ugguacaccu cggucauaac aauagaacuc      240

uccaacauaa aagaaaacaa augcaacggc accgacgcca aggucaaacu gauaaaacaa      300

gaacuugaua aauacaaaaa cgccgucacu gaacuccaac uccucaugca auccacuccc      360

gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg ucuguaaagu acuccaccuc      420

gaaggggaag ucaacaaaau caaaucagcc cuccuuagca ccaacaaggc cgucgucucc      480

cucucaaacg gagucagcgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aaacaacucc ugcccauccu aaauaaacaa uccugcucua ucuccaauau cgaaaccguu      600

auagaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      660

gcaggcguca ccaccccugu gucaaccuac augcucacca acagcgaacu acucucacuc      720

aucaaugaca ugcccaucac caacgaccaa aagaaacuca uguccaacaa cguccaaauc      780

guacgucaac aauccuacag caucaugugc aucauaaaag aagaaguccu cgccuacguc      840

guccaacuuc cccucuacgg cgucauagac acccccugcu ggaaacugca uaccucaccc      900

cuaugcacca ccaacacuaa agaaggcucc aacaucugcc ucacccgcac ggaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac uuguaaaguc     1020

caauccaaca gagucuucug cgacaccaug aacucuagaa cgcugccauc cgagguaaac     1080

cuaugcaacg ucgacaucuu caaucccaaa uacgacugca agaucaugac cucaaaaacc     1140

gacguauccu ccucaguaau caccagucuc ggagcuaucg ucuccugcua cggcaaaacc     1200

aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa ccuucucaaa cggaugcgac     1260

uacgucagca acaaaggcgu agauaccguc ucugucggca acacacugua cugcguaaac     1320

aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucguuuucc ccucagauga auuugacgcc ucgauaucac aagucaacga aaagauaaau     1440

cagucccucg ccuucauccg aaaauccgac gaacuccucc acaacguuaa cgcaggaaag     1500

uccaccacaa acaucaugau aacuacaauc auaauaguca uuaucgucau acuccucucc     1560

cuaaucgccg uaggccugcu acucuacugc aaagcccgcu caacccccgu cacucucuca     1620

aaagaccaac ucuccggcau caauaacauc gccuucucaa acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  4653
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4653
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4654
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4654
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4655
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4655
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4656
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4656
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcauucucaa     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4657
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4657
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4658
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4658
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcuuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4659
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4659
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uacucaaagc caacgcaaua acaacaauau      120

uaacagccgu aacauuuugc uucgcaucag gucaaaacau aacagaagag uucuaccaau      180

ccacaugcuc agcaguauca aaaggauauu uaagugcucu aagaacagga ugguacacau      240

ccguaauaac aaucgaacua ucaaacauaa aagaaaauaa auguaaugga acagacgcca      300

aaguaaaauu aaucaaacaa gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau      360

uauuaaugca aucaacaccg gccacaggau cuggaucagc aauaugcuca ggaguagcag      420

ucugcaaagu auuacaccua gaaggggaag uuaauaaaau caaaucagca uuacuaucca      480

ccaacaaagc gguaguuuca cucuccaacg gcguaucugu cuuaacauuc aaaguauuag      540

accuaaaaaa cuacauugac aaacaacuac uaccaauccu aaacaaacaa ucauguucca      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua uuagaaauaa      660

caagagaauu uuccgucaau gcaggaguua cuaccccugu cuccaccuau augcuaacca      720

auuccgaacu cuuaucauua auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa      780

ugagcaacaa cguacaaaua guacgacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguccu agcauacguu guacaacuac cacuauacgg agucauagau accccaugcu      900

ggaaacucca uacaagccca cuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacaagaac agaccgagga ugguacugcg auaaugccgg cucagucuca uucuuuccgc     1020

aagccgaaac uuguaaagua caaaguaaca gaguauuuug ugacaccaug aacucaagaa     1080

cccucccaag cgaagucaau cuaugcaacg uugauauauu caaucccaaa uacgacugca     1140

aaaucaugac cucaaaaaca gacgucagcu cauccguuau aacaucacua ggagccaucg     1200

uaucuugcua uggaaaaaca aaaugcacag caagcaauaa aaacagaggc auaauaaaaa     1260

cauucucaaa uggaugcgac uacguaucaa acaaaggagu cgacacaguu uccguaggaa     1320

acacuuuaua cugcguaaac aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa     1380

uaauaaacuu cuacgaucca cuuguauucc caucagacga auuugacgca ucaauuucac     1440

aaguaaacga aaaaauaaac caaucacucg cauucauaag aaaaucagau gaacuacuac     1500

auaacguaaa cgcaggaaaa uccacaacaa acaucaugau aacaaccauc auaaucguaa     1560

uaaucguaau acuauuaucc cuaauugcag uaggauuacu cuuauauugc aaagcaagau     1620

caacaccagu aacccucagu aaagaccaac uauccggaau aaauaacauc gcauucucaa     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4660
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4660
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacugcuca uccucaaagc caacgccauc accaccauuc      120

uuaccgccgu cacauucugc uucgccucag gccaaaacau caccgaagaa uuuuaccaau      180

ccacuuguuc agccgucuca aaaggauacc uaucagcccu ccguaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaacauaa aagaaaacaa augcaacggc accgacgcca      300

aggucaaacu gauaaaacaa gaacuugaua aauacaaaaa cgccgucacu gaacuccaac      360

uccucaugca auccacuccc gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg      420

ucuguaaagu acuccaccuc gaaggggaag ucaacaaaau caaaucagcc cuccuuagca      480

ccaacaaggc cgucgucucc cucucaaacg gagucagcgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aaacaacucc ugcccauccu aaauaaacaa uccugcucua      600

ucuccaauau cgaaaccguu auagaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gcaggcguca ccaccccugu gucaaccuac augcucacca      720

acagcgaacu acucucacuc aucaaugaca ugcccaucac caacgaccaa aagaaacuca      780

uguccaacaa cguccaaauc guacgucaac aauccuacag caucaugugc aucauaaaag      840

aagaaguccu cgccuacguc guccaacuuc cccucuacgg cgucauagac acccccugcu      900

ggaaacugca uaccucaccc cuaugcacca ccaacacuaa agaaggcucc aacaucugcc      960

ucacccgcac ggaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac uuguaaaguc caauccaaca gagucuucug cgacaccaug aacucuagaa     1080

cgcugccauc cgagguaaac cuaugcaacg ucgacaucuu caaucccaaa uacgacugca     1140

agaucaugac cucaaaaacc gacguauccu ccucaguaau caccagucuc ggagcuaucg     1200

ucuccugcua cggcaaaacc aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa     1260

ccuucucaaa cggaugcgac uacgucagca acaaaggcgu agauaccguc ucugucggca     1320

acacacugua cugcguaaac aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucguuuucc ccucagauga auuugacgcc ucgauaucac     1440

aagucaacga aaagauaaau cagucccucg ccuucauccg aaaauccgac gaacuccucc     1500

acaacguuaa cgcaggaaag uccaccacaa acaucaugau aacuacaauc auaauaguca     1560

uuaucgucau acuccucucc cuaaucgccg uaggccugcu acucuacugc aaagcccgcu     1620

caacccccgu cacucucuca aaagaccaac ucuccggcau caauaacauc gccuucucaa     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4661
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4661
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4662
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4662
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4663
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4663
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4664
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4664
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcauucucaa     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4665
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4665
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4666
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4666
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcuuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4667
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4667
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uacucaaagc caacgcaaua acaacaauau      120

uaacagccgu aacauuuugc uucgcaucag gucaaaacau aacagaagag uucuaccaau      180

ccacaugcuc agcaguauca aaaggauauu uaagugcucu aagaacagga ugguacacau      240

ccguaauaac aaucgaacua ucaaacauaa aagaaaauaa auguaaugga acagacgcca      300

aaguaaaauu aaucaaacaa gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau      360

uauuaaugca aucaacaccg gccacaggau cuggaucagc aauaugcuca ggaguagcag      420

ucugcaaagu auuacaccua gaaggggaag uuaauaaaau caaaucagca uuacuaucca      480

ccaacaaagc gguaguuuca cucuccaacg gcguaucugu cuuaacauuc aaaguauuag      540

accuaaaaaa cuacauugac aaacaacuac uaccaauccu aaacaaacaa ucauguucca      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua uuagaaauaa      660

caagagaauu uuccgucaau gcaggaguua cuaccccugu cuccaccuau augcuaacca      720

auuccgaacu cuuaucauua auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa      780

ugagcaacaa cguacaaaua guacgacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguccu agcauacguu guacaacuac cacuauacgg agucauagau accccaugcu      900

ggaaacucca uacaagccca cuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacaagaac agaccgagga ugguacugcg auaaugccgg cucagucuca uucuuuccgc     1020

aagccgaaac uuguaaagua caaaguaaca gaguauuuug ugacaccaug aacucaagaa     1080

cccucccaag cgaagucaau cuaugcaacg uugauauauu caaucccaaa uacgacugca     1140

aaaucaugac cucaaaaaca gacgucagcu cauccguuau aacaucacua ggagccaucg     1200

uaucuugcua uggaaaaaca aaaugcacag caagcaauaa aaacagaggc auaauaaaaa     1260

cauucucaaa uggaugcgac uacguaucaa acaaaggagu cgacacaguu uccguaggaa     1320

acacuuuaua cugcguaaac aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa     1380

uaauaaacuu cuacgaucca cuuguauucc caucagacga auuugacgca ucaauuucac     1440

aaguaaacga aaaaauaaac caaucacucg cauucauaag aaaaucagau gaacuacuac     1500

auaacguaaa cgcaggaaaa uccacaacaa acaucaugau aacaaccauc auaaucguaa     1560

uaaucguaau acuauuaucc cuaauugcag uaggauuacu cuuauauugc aaagcaagau     1620

caacaccagu aacccucagu aaagaccaac uauccggaau aaauaacauc gcauucucaa     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4668
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4668
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacugcuca uccucaaagc caacgccauc accaccauuc      120

uuaccgccgu cacauucugc uucgccucag gccaaaacau caccgaagaa uuuuaccaau      180

ccacuuguuc agccgucuca aaaggauacc uaucagcccu ccguaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaacauaa aagaaaacaa augcaacggc accgacgcca      300

aggucaaacu gauaaaacaa gaacuugaua aauacaaaaa cgccgucacu gaacuccaac      360

uccucaugca auccacuccc gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg      420

ucuguaaagu acuccaccuc gaaggggaag ucaacaaaau caaaucagcc cuccuuagca      480

ccaacaaggc cgucgucucc cucucaaacg gagucagcgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aaacaacucc ugcccauccu aaauaaacaa uccugcucua      600

ucuccaauau cgaaaccguu auagaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gcaggcguca ccaccccugu gucaaccuac augcucacca      720

acagcgaacu acucucacuc aucaaugaca ugcccaucac caacgaccaa aagaaacuca      780

uguccaacaa cguccaaauc guacgucaac aauccuacag caucaugugc aucauaaaag      840

aagaaguccu cgccuacguc guccaacuuc cccucuacgg cgucauagac acccccugcu      900

ggaaacugca uaccucaccc cuaugcacca ccaacacuaa agaaggcucc aacaucugcc      960

ucacccgcac ggaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac uuguaaaguc caauccaaca gagucuucug cgacaccaug aacucuagaa     1080

cgcugccauc cgagguaaac cuaugcaacg ucgacaucuu caaucccaaa uacgacugca     1140

agaucaugac cucaaaaacc gacguauccu ccucaguaau caccagucuc ggagcuaucg     1200

ucuccugcua cggcaaaacc aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa     1260

ccuucucaaa cggaugcgac uacgucagca acaaaggcgu agauaccguc ucugucggca     1320

acacacugua cugcguaaac aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucguuuucc ccucagauga auuugacgcc ucgauaucac     1440

aagucaacga aaagauaaau cagucccucg ccuucauccg aaaauccgac gaacuccucc     1500

acaacguuaa cgcaggaaag uccaccacaa acaucaugau aacuacaauc auaauaguca     1560

uuaucgucau acuccucucc cuaaucgccg uaggccugcu acucuacugc aaagcccgcu     1620

caacccccgu cacucucuca aaagaccaac ucuccggcau caauaacauc gccuucucaa     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  4669
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4669
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4670
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4670
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4671
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4671
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4672
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4672
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcau ucucaaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4673
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4673
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4674
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4674
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcuu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4675
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4675
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauacu caaagccaac gcaauaacaa caauauuaac agccguaaca      180

uuuugcuucg caucagguca aaacauaaca gaagaguucu accaauccac augcucagca      240

guaucaaaag gauauuuaag ugcucuaaga acaggauggu acacauccgu aauaacaauc      300

gaacuaucaa acauaaaaga aaauaaaugu aauggaacag acgccaaagu aaaauuaauc      360

aaacaagaac uagacaaaua caaaaacgca guuacugaau uacaauuauu aaugcaauca      420

acaccggcca caggaucugg aucagcaaua ugcucaggag uagcagucug caaaguauua      480

caccuagaag gggaaguuaa uaaaaucaaa ucagcauuac uauccaccaa caaagcggua      540

guuucacucu ccaacggcgu aucugucuua acauucaaag uauuagaccu aaaaaacuac      600

auugacaaac aacuacuacc aauccuaaac aaacaaucau guuccauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuauuag aaauaacaag agaauuuucc      720

gucaaugcag gaguuacuac cccugucucc accuauaugc uaaccaauuc cgaacucuua      780

ucauuaauaa acgacaugcc uaucacaaau gaccaaaaaa aauuaaugag caacaacgua      840

caaauaguac gacaacaauc auacucaauc augugcauaa uaaaagaaga aguccuagca      900

uacguuguac aacuaccacu auacggaguc auagauaccc caugcuggaa acuccauaca      960

agcccacuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac aagaacagac     1020

cgaggauggu acugcgauaa ugccggcuca gucucauucu uuccgcaagc cgaaacuugu     1080

aaaguacaaa guaacagagu auuuugugac accaugaacu caagaacccu cccaagcgaa     1140

gucaaucuau gcaacguuga uauauucaau cccaaauacg acugcaaaau caugaccuca     1200

aaaacagacg ucagcucauc cguuauaaca ucacuaggag ccaucguauc uugcuaugga     1260

aaaacaaaau gcacagcaag caauaaaaac agaggcauaa uaaaaacauu cucaaaugga     1320

ugcgacuacg uaucaaacaa aggagucgac acaguuuccg uaggaaacac uuuauacugc     1380

guaaacaaac aagaaggaaa aucauuauac gucaaaggug aaccaauaau aaacuucuac     1440

gauccacuug uauucccauc agacgaauuu gacgcaucaa uuucacaagu aaacgaaaaa     1500

auaaaccaau cacucgcauu cauaagaaaa ucagaugaac uacuacauaa cguaaacgca     1560

ggaaaaucca caacaaacau caugauaaca accaucauaa ucguaauaau cguaauacua     1620

uuaucccuaa uugcaguagg auuacucuua uauugcaaag caagaucaac accaguaacc     1680

cucaguaaag accaacuauc cggaauaaau aacaucgcau ucucaaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4676
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4676
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac ugcucauccu caaagccaac gccaucacca ccauucuuac cgccgucaca      180

uucugcuucg ccucaggcca aaacaucacc gaagaauuuu accaauccac uuguucagcc      240

gucucaaaag gauaccuauc agcccuccgu accggcuggu acaccucggu cauaacaaua      300

gaacucucca acauaaaaga aaacaaaugc aacggcaccg acgccaaggu caaacugaua      360

aaacaagaac uugauaaaua caaaaacgcc gucacugaac uccaacuccu caugcaaucc      420

acucccgcua cuggcucugg cuccgccauc ugcucuggcg ucgccgucug uaaaguacuc      480

caccucgaag gggaagucaa caaaaucaaa ucagcccucc uuagcaccaa caaggccguc      540

gucucccucu caaacggagu cagcguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaaac aacuccugcc cauccuaaau aaacaauccu gcucuaucuc caauaucgaa      660

accguuauag aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgcag gcgucaccac cccuguguca accuacaugc ucaccaacag cgaacuacuc      780

ucacucauca augacaugcc caucaccaac gaccaaaaga aacucauguc caacaacguc      840

caaaucguac gucaacaauc cuacagcauc augugcauca uaaaagaaga aguccucgcc      900

uacgucgucc aacuuccccu cuacggcguc auagacaccc ccugcuggaa acugcauacc      960

ucaccccuau gcaccaccaa cacuaaagaa ggcuccaaca ucugccucac ccgcacggac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaacuugu     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cuagaacgcu gccauccgag     1140

guaaaccuau gcaacgucga caucuucaau cccaaauacg acugcaagau caugaccuca     1200

aaaaccgacg uauccuccuc aguaaucacc agucucggag cuaucgucuc cugcuacggc     1260

aaaaccaaau gcacggccuc uaacaaaaac cgcggcauca ucaaaaccuu cucaaacgga     1320

ugcgacuacg ucagcaacaa aggcguagau accgucucug ucggcaacac acuguacugc     1380

guaaacaagc aagaaggaaa aucccucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg uuuuccccuc agaugaauuu gacgccucga uaucacaagu caacgaaaag     1500

auaaaucagu cccucgccuu cauccgaaaa uccgacgaac uccuccacaa cguuaacgca     1560

ggaaagucca ccacaaacau caugauaacu acaaucauaa uagucauuau cgucauacuc     1620

cucucccuaa ucgccguagg ccugcuacuc uacugcaaag cccgcucaac ccccgucacu     1680

cucucaaaag accaacucuc cggcaucaau aacaucgccu ucucaaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  4677
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4677
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4678
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4678
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4679
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4679
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4680
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4680
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cauucucaaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4681
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4681
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4682
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4682
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cuuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4683
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4683
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau acucaaagcc      120

aacgcaauaa caacaauauu aacagccgua acauuuugcu ucgcaucagg ucaaaacaua      180

acagaagagu ucuaccaauc cacaugcuca gcaguaucaa aaggauauuu aagugcucua      240

agaacaggau gguacacauc cguaauaaca aucgaacuau caaacauaaa agaaaauaaa      300

uguaauggaa cagacgccaa aguaaaauua aucaaacaag aacuagacaa auacaaaaac      360

gcaguuacug aauuacaauu auuaaugcaa ucaacaccgg ccacaggauc uggaucagca      420

auaugcucag gaguagcagu cugcaaagua uuacaccuag aaggggaagu uaauaaaauc      480

aaaucagcau uacuauccac caacaaagcg guaguuucac ucuccaacgg cguaucuguc      540

uuaacauuca aaguauuaga ccuaaaaaac uacauugaca aacaacuacu accaauccua      600

aacaaacaau cauguuccau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuau uagaaauaac aagagaauuu uccgucaaug caggaguuac uaccccuguc      720

uccaccuaua ugcuaaccaa uuccgaacuc uuaucauuaa uaaacgacau gccuaucaca      780

aaugaccaaa aaaaauuaau gagcaacaac guacaaauag uacgacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguccua gcauacguug uacaacuacc acuauacgga      900

gucauagaua ccccaugcug gaaacuccau acaagcccac uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacaagaaca gaccgaggau gguacugcga uaaugccggc     1020

ucagucucau ucuuuccgca agccgaaacu uguaaaguac aaaguaacag aguauuuugu     1080

gacaccauga acucaagaac ccucccaagc gaagucaauc uaugcaacgu ugauauauuc     1140

aaucccaaau acgacugcaa aaucaugacc ucaaaaacag acgucagcuc auccguuaua     1200

acaucacuag gagccaucgu aucuugcuau ggaaaaacaa aaugcacagc aagcaauaaa     1260

aacagaggca uaauaaaaac auucucaaau ggaugcgacu acguaucaaa caaaggaguc     1320

gacacaguuu ccguaggaaa cacuuuauac ugcguaaaca aacaagaagg aaaaucauua     1380

uacgucaaag gugaaccaau aauaaacuuc uacgauccac uuguauuccc aucagacgaa     1440

uuugacgcau caauuucaca aguaaacgaa aaaauaaacc aaucacucgc auucauaaga     1500

aaaucagaug aacuacuaca uaacguaaac gcaggaaaau ccacaacaaa caucaugaua     1560

acaaccauca uaaucguaau aaucguaaua cuauuauccc uaauugcagu aggauuacuc     1620

uuauauugca aagcaagauc aacaccagua acccucagua aagaccaacu auccggaaua     1680

aauaacaucg cauucucaaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4684
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4684
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacugcucau ccucaaagcc      120

aacgccauca ccaccauucu uaccgccguc acauucugcu ucgccucagg ccaaaacauc      180

accgaagaau uuuaccaauc cacuuguuca gccgucucaa aaggauaccu aucagcccuc      240

cguaccggcu gguacaccuc ggucauaaca auagaacucu ccaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa ggucaaacug auaaaacaag aacuugauaa auacaaaaac      360

gccgucacug aacuccaacu ccucaugcaa uccacucccg cuacuggcuc uggcuccgcc      420

aucugcucug gcgucgccgu cuguaaagua cuccaccucg aaggggaagu caacaaaauc      480

aaaucagccc uccuuagcac caacaaggcc gucgucuccc ucucaaacgg agucagcguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca aacaacuccu gcccauccua      600

aauaaacaau ccugcucuau cuccaauauc gaaaccguua uagaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg caggcgucac caccccugug      720

ucaaccuaca ugcucaccaa cagcgaacua cucucacuca ucaaugacau gcccaucacc      780

aacgaccaaa agaaacucau guccaacaac guccaaaucg uacgucaaca auccuacagc      840

aucaugugca ucauaaaaga agaaguccuc gccuacgucg uccaacuucc ccucuacggc      900

gucauagaca cccccugcug gaaacugcau accucacccc uaugcaccac caacacuaaa      960

gaaggcucca acaucugccu cacccgcacg gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacu uguaaagucc aauccaacag agucuucugc     1080

gacaccauga acucuagaac gcugccaucc gagguaaacc uaugcaacgu cgacaucuuc     1140

aaucccaaau acgacugcaa gaucaugacc ucaaaaaccg acguauccuc cucaguaauc     1200

accagucucg gagcuaucgu cuccugcuac ggcaaaacca aaugcacggc cucuaacaaa     1260

aaccgcggca ucaucaaaac cuucucaaac ggaugcgacu acgucagcaa caaaggcgua     1320

gauaccgucu cugucggcaa cacacuguac ugcguaaaca agcaagaagg aaaaucccuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucguuuuccc cucagaugaa     1440

uuugacgccu cgauaucaca agucaacgaa aagauaaauc agucccucgc cuucauccga     1500

aaauccgacg aacuccucca caacguuaac gcaggaaagu ccaccacaaa caucaugaua     1560

acuacaauca uaauagucau uaucgucaua cuccucuccc uaaucgccgu aggccugcua     1620

cucuacugca aagcccgcuc aacccccguc acucucucaa aagaccaacu cuccggcauc     1680

aauaacaucg ccuucucaaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  4685
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4685
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4686
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4686
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4687
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4687
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4688
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4688
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcau ucucaaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4689
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4689
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4690
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4690
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcuu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4691
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4691
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauacu caaagccaac gcaauaacaa caauauuaac agccguaaca      180

uuuugcuucg caucagguca aaacauaaca gaagaguucu accaauccac augcucagca      240

guaucaaaag gauauuuaag ugcucuaaga acaggauggu acacauccgu aauaacaauc      300

gaacuaucaa acauaaaaga aaauaaaugu aauggaacag acgccaaagu aaaauuaauc      360

aaacaagaac uagacaaaua caaaaacgca guuacugaau uacaauuauu aaugcaauca      420

acaccggcca caggaucugg aucagcaaua ugcucaggag uagcagucug caaaguauua      480

caccuagaag gggaaguuaa uaaaaucaaa ucagcauuac uauccaccaa caaagcggua      540

guuucacucu ccaacggcgu aucugucuua acauucaaag uauuagaccu aaaaaacuac      600

auugacaaac aacuacuacc aauccuaaac aaacaaucau guuccauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuauuag aaauaacaag agaauuuucc      720

gucaaugcag gaguuacuac cccugucucc accuauaugc uaaccaauuc cgaacucuua      780

ucauuaauaa acgacaugcc uaucacaaau gaccaaaaaa aauuaaugag caacaacgua      840

caaauaguac gacaacaauc auacucaauc augugcauaa uaaaagaaga aguccuagca      900

uacguuguac aacuaccacu auacggaguc auagauaccc caugcuggaa acuccauaca      960

agcccacuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac aagaacagac     1020

cgaggauggu acugcgauaa ugccggcuca gucucauucu uuccgcaagc cgaaacuugu     1080

aaaguacaaa guaacagagu auuuugugac accaugaacu caagaacccu cccaagcgaa     1140

gucaaucuau gcaacguuga uauauucaau cccaaauacg acugcaaaau caugaccuca     1200

aaaacagacg ucagcucauc cguuauaaca ucacuaggag ccaucguauc uugcuaugga     1260

aaaacaaaau gcacagcaag caauaaaaac agaggcauaa uaaaaacauu cucaaaugga     1320

ugcgacuacg uaucaaacaa aggagucgac acaguuuccg uaggaaacac uuuauacugc     1380

guaaacaaac aagaaggaaa aucauuauac gucaaaggug aaccaauaau aaacuucuac     1440

gauccacuug uauucccauc agacgaauuu gacgcaucaa uuucacaagu aaacgaaaaa     1500

auaaaccaau cacucgcauu cauaagaaaa ucagaugaac uacuacauaa cguaaacgca     1560

ggaaaaucca caacaaacau caugauaaca accaucauaa ucguaauaau cguaauacua     1620

uuaucccuaa uugcaguagg auuacucuua uauugcaaag caagaucaac accaguaacc     1680

cucaguaaag accaacuauc cggaauaaau aacaucgcau ucucaaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4692
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4692
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac ugcucauccu caaagccaac gccaucacca ccauucuuac cgccgucaca      180

uucugcuucg ccucaggcca aaacaucacc gaagaauuuu accaauccac uuguucagcc      240

gucucaaaag gauaccuauc agcccuccgu accggcuggu acaccucggu cauaacaaua      300

gaacucucca acauaaaaga aaacaaaugc aacggcaccg acgccaaggu caaacugaua      360

aaacaagaac uugauaaaua caaaaacgcc gucacugaac uccaacuccu caugcaaucc      420

acucccgcua cuggcucugg cuccgccauc ugcucuggcg ucgccgucug uaaaguacuc      480

caccucgaag gggaagucaa caaaaucaaa ucagcccucc uuagcaccaa caaggccguc      540

gucucccucu caaacggagu cagcguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaaac aacuccugcc cauccuaaau aaacaauccu gcucuaucuc caauaucgaa      660

accguuauag aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgcag gcgucaccac cccuguguca accuacaugc ucaccaacag cgaacuacuc      780

ucacucauca augacaugcc caucaccaac gaccaaaaga aacucauguc caacaacguc      840

caaaucguac gucaacaauc cuacagcauc augugcauca uaaaagaaga aguccucgcc      900

uacgucgucc aacuuccccu cuacggcguc auagacaccc ccugcuggaa acugcauacc      960

ucaccccuau gcaccaccaa cacuaaagaa ggcuccaaca ucugccucac ccgcacggac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaacuugu     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cuagaacgcu gccauccgag     1140

guaaaccuau gcaacgucga caucuucaau cccaaauacg acugcaagau caugaccuca     1200

aaaaccgacg uauccuccuc aguaaucacc agucucggag cuaucgucuc cugcuacggc     1260

aaaaccaaau gcacggccuc uaacaaaaac cgcggcauca ucaaaaccuu cucaaacgga     1320

ugcgacuacg ucagcaacaa aggcguagau accgucucug ucggcaacac acuguacugc     1380

guaaacaagc aagaaggaaa aucccucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg uuuuccccuc agaugaauuu gacgccucga uaucacaagu caacgaaaag     1500

auaaaucagu cccucgccuu cauccgaaaa uccgacgaac uccuccacaa cguuaacgca     1560

ggaaagucca ccacaaacau caugauaacu acaaucauaa uagucauuau cgucauacuc     1620

cucucccuaa ucgccguagg ccugcuacuc uacugcaaag cccgcucaac ccccgucacu     1680

cucucaaaag accaacucuc cggcaucaau aacaucgccu ucucaaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  4693
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4693
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4694
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4694
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4695
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4695
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4696
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4696
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cauucucaaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4697
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4697
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4698
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4698
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cuuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4699
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4699
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau acucaaagcc      120

aacgcaauaa caacaauauu aacagccgua acauuuugcu ucgcaucagg ucaaaacaua      180

acagaagagu ucuaccaauc cacaugcuca gcaguaucaa aaggauauuu aagugcucua      240

agaacaggau gguacacauc cguaauaaca aucgaacuau caaacauaaa agaaaauaaa      300

uguaauggaa cagacgccaa aguaaaauua aucaaacaag aacuagacaa auacaaaaac      360

gcaguuacug aauuacaauu auuaaugcaa ucaacaccgg ccacaggauc uggaucagca      420

auaugcucag gaguagcagu cugcaaagua uuacaccuag aaggggaagu uaauaaaauc      480

aaaucagcau uacuauccac caacaaagcg guaguuucac ucuccaacgg cguaucuguc      540

uuaacauuca aaguauuaga ccuaaaaaac uacauugaca aacaacuacu accaauccua      600

aacaaacaau cauguuccau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuau uagaaauaac aagagaauuu uccgucaaug caggaguuac uaccccuguc      720

uccaccuaua ugcuaaccaa uuccgaacuc uuaucauuaa uaaacgacau gccuaucaca      780

aaugaccaaa aaaaauuaau gagcaacaac guacaaauag uacgacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguccua gcauacguug uacaacuacc acuauacgga      900

gucauagaua ccccaugcug gaaacuccau acaagcccac uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacaagaaca gaccgaggau gguacugcga uaaugccggc     1020

ucagucucau ucuuuccgca agccgaaacu uguaaaguac aaaguaacag aguauuuugu     1080

gacaccauga acucaagaac ccucccaagc gaagucaauc uaugcaacgu ugauauauuc     1140

aaucccaaau acgacugcaa aaucaugacc ucaaaaacag acgucagcuc auccguuaua     1200

acaucacuag gagccaucgu aucuugcuau ggaaaaacaa aaugcacagc aagcaauaaa     1260

aacagaggca uaauaaaaac auucucaaau ggaugcgacu acguaucaaa caaaggaguc     1320

gacacaguuu ccguaggaaa cacuuuauac ugcguaaaca aacaagaagg aaaaucauua     1380

uacgucaaag gugaaccaau aauaaacuuc uacgauccac uuguauuccc aucagacgaa     1440

uuugacgcau caauuucaca aguaaacgaa aaaauaaacc aaucacucgc auucauaaga     1500

aaaucagaug aacuacuaca uaacguaaac gcaggaaaau ccacaacaaa caucaugaua     1560

acaaccauca uaaucguaau aaucguaaua cuauuauccc uaauugcagu aggauuacuc     1620

uuauauugca aagcaagauc aacaccagua acccucagua aagaccaacu auccggaaua     1680

aauaacaucg cauucucaaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4700
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4700
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacugcucau ccucaaagcc      120

aacgccauca ccaccauucu uaccgccguc acauucugcu ucgccucagg ccaaaacauc      180

accgaagaau uuuaccaauc cacuuguuca gccgucucaa aaggauaccu aucagcccuc      240

cguaccggcu gguacaccuc ggucauaaca auagaacucu ccaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa ggucaaacug auaaaacaag aacuugauaa auacaaaaac      360

gccgucacug aacuccaacu ccucaugcaa uccacucccg cuacuggcuc uggcuccgcc      420

aucugcucug gcgucgccgu cuguaaagua cuccaccucg aaggggaagu caacaaaauc      480

aaaucagccc uccuuagcac caacaaggcc gucgucuccc ucucaaacgg agucagcguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca aacaacuccu gcccauccua      600

aauaaacaau ccugcucuau cuccaauauc gaaaccguua uagaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg caggcgucac caccccugug      720

ucaaccuaca ugcucaccaa cagcgaacua cucucacuca ucaaugacau gcccaucacc      780

aacgaccaaa agaaacucau guccaacaac guccaaaucg uacgucaaca auccuacagc      840

aucaugugca ucauaaaaga agaaguccuc gccuacgucg uccaacuucc ccucuacggc      900

gucauagaca cccccugcug gaaacugcau accucacccc uaugcaccac caacacuaaa      960

gaaggcucca acaucugccu cacccgcacg gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacu uguaaagucc aauccaacag agucuucugc     1080

gacaccauga acucuagaac gcugccaucc gagguaaacc uaugcaacgu cgacaucuuc     1140

aaucccaaau acgacugcaa gaucaugacc ucaaaaaccg acguauccuc cucaguaauc     1200

accagucucg gagcuaucgu cuccugcuac ggcaaaacca aaugcacggc cucuaacaaa     1260

aaccgcggca ucaucaaaac cuucucaaac ggaugcgacu acgucagcaa caaaggcgua     1320

gauaccgucu cugucggcaa cacacuguac ugcguaaaca agcaagaagg aaaaucccuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucguuuuccc cucagaugaa     1440

uuugacgccu cgauaucaca agucaacgaa aagauaaauc agucccucgc cuucauccga     1500

aaauccgacg aacuccucca caacguuaac gcaggaaagu ccaccacaaa caucaugaua     1560

acuacaauca uaauagucau uaucgucaua cuccucuccc uaaucgccgu aggccugcua     1620

cucuacugca aagcccgcuc aacccccguc acucucucaa aagaccaacu cuccggcauc     1680

aauaacaucg ccuucucaaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  4701
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4701
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4702
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4702
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4703
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4703
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4704
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4704
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cauucucaaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4705
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4705
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4706
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4706
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cuuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4707
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4707
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau acucaaagcc      120

aacgcaauaa caacaauauu aacagccgua acauuuugcu ucgcaucagg ucaaaacaua      180

acagaagagu ucuaccaauc cacaugcuca gcaguaucaa aaggauauuu aagugcucua      240

agaacaggau gguacacauc cguaauaaca aucgaacuau caaacauaaa agaaaauaaa      300

uguaauggaa cagacgccaa aguaaaauua aucaaacaag aacuagacaa auacaaaaac      360

gcaguuacug aauuacaauu auuaaugcaa ucaacaccgg ccacaggauc uggaucagca      420

auaugcucag gaguagcagu cugcaaagua uuacaccuag aaggggaagu uaauaaaauc      480

aaaucagcau uacuauccac caacaaagcg guaguuucac ucuccaacgg cguaucuguc      540

uuaacauuca aaguauuaga ccuaaaaaac uacauugaca aacaacuacu accaauccua      600

aacaaacaau cauguuccau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuau uagaaauaac aagagaauuu uccgucaaug caggaguuac uaccccuguc      720

uccaccuaua ugcuaaccaa uuccgaacuc uuaucauuaa uaaacgacau gccuaucaca      780

aaugaccaaa aaaaauuaau gagcaacaac guacaaauag uacgacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguccua gcauacguug uacaacuacc acuauacgga      900

gucauagaua ccccaugcug gaaacuccau acaagcccac uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacaagaaca gaccgaggau gguacugcga uaaugccggc     1020

ucagucucau ucuuuccgca agccgaaacu uguaaaguac aaaguaacag aguauuuugu     1080

gacaccauga acucaagaac ccucccaagc gaagucaauc uaugcaacgu ugauauauuc     1140

aaucccaaau acgacugcaa aaucaugacc ucaaaaacag acgucagcuc auccguuaua     1200

acaucacuag gagccaucgu aucuugcuau ggaaaaacaa aaugcacagc aagcaauaaa     1260

aacagaggca uaauaaaaac auucucaaau ggaugcgacu acguaucaaa caaaggaguc     1320

gacacaguuu ccguaggaaa cacuuuauac ugcguaaaca aacaagaagg aaaaucauua     1380

uacgucaaag gugaaccaau aauaaacuuc uacgauccac uuguauuccc aucagacgaa     1440

uuugacgcau caauuucaca aguaaacgaa aaaauaaacc aaucacucgc auucauaaga     1500

aaaucagaug aacuacuaca uaacguaaac gcaggaaaau ccacaacaaa caucaugaua     1560

acaaccauca uaaucguaau aaucguaaua cuauuauccc uaauugcagu aggauuacuc     1620

uuauauugca aagcaagauc aacaccagua acccucagua aagaccaacu auccggaaua     1680

aauaacaucg cauucucaaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4708
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4708
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacugcucau ccucaaagcc      120

aacgccauca ccaccauucu uaccgccguc acauucugcu ucgccucagg ccaaaacauc      180

accgaagaau uuuaccaauc cacuuguuca gccgucucaa aaggauaccu aucagcccuc      240

cguaccggcu gguacaccuc ggucauaaca auagaacucu ccaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa ggucaaacug auaaaacaag aacuugauaa auacaaaaac      360

gccgucacug aacuccaacu ccucaugcaa uccacucccg cuacuggcuc uggcuccgcc      420

aucugcucug gcgucgccgu cuguaaagua cuccaccucg aaggggaagu caacaaaauc      480

aaaucagccc uccuuagcac caacaaggcc gucgucuccc ucucaaacgg agucagcguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca aacaacuccu gcccauccua      600

aauaaacaau ccugcucuau cuccaauauc gaaaccguua uagaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg caggcgucac caccccugug      720

ucaaccuaca ugcucaccaa cagcgaacua cucucacuca ucaaugacau gcccaucacc      780

aacgaccaaa agaaacucau guccaacaac guccaaaucg uacgucaaca auccuacagc      840

aucaugugca ucauaaaaga agaaguccuc gccuacgucg uccaacuucc ccucuacggc      900

gucauagaca cccccugcug gaaacugcau accucacccc uaugcaccac caacacuaaa      960

gaaggcucca acaucugccu cacccgcacg gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacu uguaaagucc aauccaacag agucuucugc     1080

gacaccauga acucuagaac gcugccaucc gagguaaacc uaugcaacgu cgacaucuuc     1140

aaucccaaau acgacugcaa gaucaugacc ucaaaaaccg acguauccuc cucaguaauc     1200

accagucucg gagcuaucgu cuccugcuac ggcaaaacca aaugcacggc cucuaacaaa     1260

aaccgcggca ucaucaaaac cuucucaaac ggaugcgacu acgucagcaa caaaggcgua     1320

gauaccgucu cugucggcaa cacacuguac ugcguaaaca agcaagaagg aaaaucccuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucguuuuccc cucagaugaa     1440

uuugacgccu cgauaucaca agucaacgaa aagauaaauc agucccucgc cuucauccga     1500

aaauccgacg aacuccucca caacguuaac gcaggaaagu ccaccacaaa caucaugaua     1560

acuacaauca uaauagucau uaucgucaua cuccucuccc uaaucgccgu aggccugcua     1620

cucuacugca aagcccgcuc aacccccguc acucucucaa aagaccaacu cuccggcauc     1680

aauaacaucg ccuucucaaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  4709
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4709
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4710
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4710
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4711
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4711
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4712
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4712
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcauucu caaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4713
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4713
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4714
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4714
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcuuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4715
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4715
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauacucaa agccaacgca      120

auaacaacaa uauuaacagc cguaacauuu ugcuucgcau caggucaaaa cauaacagaa      180

gaguucuacc aauccacaug cucagcagua ucaaaaggau auuuaagugc ucuaagaaca      240

ggaugguaca cauccguaau aacaaucgaa cuaucaaaca uaaaagaaaa uaaauguaau      300

ggaacagacg ccaaaguaaa auuaaucaaa caagaacuag acaaauacaa aaacgcaguu      360

acugaauuac aauuauuaau gcaaucaaca ccggccacag gaucuggauc agcaauaugc      420

ucaggaguag cagucugcaa aguauuacac cuagaagggg aaguuaauaa aaucaaauca      480

gcauuacuau ccaccaacaa agcgguaguu ucacucucca acggcguauc ugucuuaaca      540

uucaaaguau uagaccuaaa aaacuacauu gacaaacaac uacuaccaau ccuaaacaaa      600

caaucauguu ccauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuauuagaaa uaacaagaga auuuuccguc aaugcaggag uuacuacccc ugucuccacc      720

uauaugcuaa ccaauuccga acucuuauca uuaauaaacg acaugccuau cacaaaugac      780

caaaaaaaau uaaugagcaa caacguacaa auaguacgac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu ccuagcauac guuguacaac uaccacuaua cggagucaua      900

gauaccccau gcuggaaacu ccauacaagc ccacuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacaag aacagaccga ggaugguacu gcgauaaugc cggcucaguc     1020

ucauucuuuc cgcaagccga aacuuguaaa guacaaagua acagaguauu uugugacacc     1080

augaacucaa gaacccuccc aagcgaaguc aaucuaugca acguugauau auucaauccc     1140

aaauacgacu gcaaaaucau gaccucaaaa acagacguca gcucauccgu uauaacauca     1200

cuaggagcca ucguaucuug cuauggaaaa acaaaaugca cagcaagcaa uaaaaacaga     1260

ggcauaauaa aaacauucuc aaauggaugc gacuacguau caaacaaagg agucgacaca     1320

guuuccguag gaaacacuuu auacugcgua aacaaacaag aaggaaaauc auuauacguc     1380

aaaggugaac caauaauaaa cuucuacgau ccacuuguau ucccaucaga cgaauuugac     1440

gcaucaauuu cacaaguaaa cgaaaaaaua aaccaaucac ucgcauucau aagaaaauca     1500

gaugaacuac uacauaacgu aaacgcagga aaauccacaa caaacaucau gauaacaacc     1560

aucauaaucg uaauaaucgu aauacuauua ucccuaauug caguaggauu acucuuauau     1620

ugcaaagcaa gaucaacacc aguaacccuc aguaaagacc aacuauccgg aauaaauaac     1680

aucgcauucu caaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4716
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4716
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacugc ucauccucaa agccaacgcc      120

aucaccacca uucuuaccgc cgucacauuc ugcuucgccu caggccaaaa caucaccgaa      180

gaauuuuacc aauccacuug uucagccguc ucaaaaggau accuaucagc ccuccguacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaggucaa acugauaaaa caagaacuug auaaauacaa aaacgccguc      360

acugaacucc aacuccucau gcaauccacu cccgcuacug gcucuggcuc cgccaucugc      420

ucuggcgucg ccgucuguaa aguacuccac cucgaagggg aagucaacaa aaucaaauca      480

gcccuccuua gcaccaacaa ggccgucguc ucccucucaa acggagucag cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaaacaac uccugcccau ccuaaauaaa      600

caauccugcu cuaucuccaa uaucgaaacc guuauagagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgcaggcg ucaccacccc ugugucaacc      720

uacaugcuca ccaacagcga acuacucuca cucaucaaug acaugcccau caccaacgac      780

caaaagaaac ucauguccaa caacguccaa aucguacguc aacaauccua cagcaucaug      840

ugcaucauaa aagaagaagu ccucgccuac gucguccaac uuccccucua cggcgucaua      900

gacacccccu gcuggaaacu gcauaccuca ccccuaugca ccaccaacac uaaagaaggc      960

uccaacaucu gccucacccg cacggaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aacuuguaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucua gaacgcugcc auccgaggua aaccuaugca acgucgacau cuucaauccc     1140

aaauacgacu gcaagaucau gaccucaaaa accgacguau ccuccucagu aaucaccagu     1200

cucggagcua ucgucuccug cuacggcaaa accaaaugca cggccucuaa caaaaaccgc     1260

ggcaucauca aaaccuucuc aaacggaugc gacuacguca gcaacaaagg cguagauacc     1320

gucucugucg gcaacacacu guacugcgua aacaagcaag aaggaaaauc ccucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucguuu uccccucaga ugaauuugac     1440

gccucgauau cacaagucaa cgaaaagaua aaucaguccc ucgccuucau ccgaaaaucc     1500

gacgaacucc uccacaacgu uaacgcagga aaguccacca caaacaucau gauaacuaca     1560

aucauaauag ucauuaucgu cauacuccuc ucccuaaucg ccguaggccu gcuacucuac     1620

ugcaaagccc gcucaacccc cgucacucuc ucaaaagacc aacucuccgg caucaauaac     1680

aucgccuucu caaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  4717
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4717
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4718
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4718
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4719
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4719
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4720
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4720
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcauucuc aaacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4721
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4721
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4722
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4722
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcuuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4723
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4723
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauacucaaa      120

gccaacgcaa uaacaacaau auuaacagcc guaacauuuu gcuucgcauc aggucaaaac      180

auaacagaag aguucuacca auccacaugc ucagcaguau caaaaggaua uuuaagugcu      240

cuaagaacag gaugguacac auccguaaua acaaucgaac uaucaaacau aaaagaaaau      300

aaauguaaug gaacagacgc caaaguaaaa uuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguua cugaauuaca auuauuaaug caaucaacac cggccacagg aucuggauca      420

gcaauaugcu caggaguagc agucugcaaa guauuacacc uagaagggga aguuaauaaa      480

aucaaaucag cauuacuauc caccaacaaa gcgguaguuu cacucuccaa cggcguaucu      540

gucuuaacau ucaaaguauu agaccuaaaa aacuacauug acaaacaacu acuaccaauc      600

cuaaacaaac aaucauguuc cauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uauuagaaau aacaagagaa uuuuccguca augcaggagu uacuaccccu      720

gucuccaccu auaugcuaac caauuccgaa cucuuaucau uaauaaacga caugccuauc      780

acaaaugacc aaaaaaaauu aaugagcaac aacguacaaa uaguacgaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguc cuagcauacg uuguacaacu accacuauac      900

ggagucauag auaccccaug cuggaaacuc cauacaagcc cacuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacaaga acagaccgag gaugguacug cgauaaugcc     1020

ggcucagucu cauucuuucc gcaagccgaa acuuguaaag uacaaaguaa cagaguauuu     1080

ugugacacca ugaacucaag aacccuccca agcgaaguca aucuaugcaa cguugauaua     1140

uucaauccca aauacgacug caaaaucaug accucaaaaa cagacgucag cucauccguu     1200

auaacaucac uaggagccau cguaucuugc uauggaaaaa caaaaugcac agcaagcaau     1260

aaaaacagag gcauaauaaa aacauucuca aauggaugcg acuacguauc aaacaaagga     1320

gucgacacag uuuccguagg aaacacuuua uacugcguaa acaaacaaga aggaaaauca     1380

uuauacguca aaggugaacc aauaauaaac uucuacgauc cacuuguauu cccaucagac     1440

gaauuugacg caucaauuuc acaaguaaac gaaaaaauaa accaaucacu cgcauucaua     1500

agaaaaucag augaacuacu acauaacgua aacgcaggaa aauccacaac aaacaucaug     1560

auaacaacca ucauaaucgu aauaaucgua auacuauuau cccuaauugc aguaggauua     1620

cucuuauauu gcaaagcaag aucaacacca guaacccuca guaaagacca acuauccgga     1680

auaaauaaca ucgcauucuc aaacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4724
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4724
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacugcu cauccucaaa      120

gccaacgcca ucaccaccau ucuuaccgcc gucacauucu gcuucgccuc aggccaaaac      180

aucaccgaag aauuuuacca auccacuugu ucagccgucu caaaaggaua ccuaucagcc      240

cuccguaccg gcugguacac cucggucaua acaauagaac ucuccaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaggucaaa cugauaaaac aagaacuuga uaaauacaaa      360

aacgccguca cugaacucca acuccucaug caauccacuc ccgcuacugg cucuggcucc      420

gccaucugcu cuggcgucgc cgucuguaaa guacuccacc ucgaagggga agucaacaaa      480

aucaaaucag cccuccuuag caccaacaag gccgucgucu cccucucaaa cggagucagc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaaacaacu ccugcccauc      600

cuaaauaaac aauccugcuc uaucuccaau aucgaaaccg uuauagaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccaccccu      720

gugucaaccu acaugcucac caacagcgaa cuacucucac ucaucaauga caugcccauc      780

accaacgacc aaaagaaacu cauguccaac aacguccaaa ucguacguca acaauccuac      840

agcaucaugu gcaucauaaa agaagaaguc cucgccuacg ucguccaacu uccccucuac      900

ggcgucauag acacccccug cuggaaacug cauaccucac cccuaugcac caccaacacu      960

aaagaaggcu ccaacaucug ccucacccgc acggaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa acuuguaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucuag aacgcugcca uccgagguaa accuaugcaa cgucgacauc     1140

uucaauccca aauacgacug caagaucaug accucaaaaa ccgacguauc cuccucagua     1200

aucaccaguc ucggagcuau cgucuccugc uacggcaaaa ccaaaugcac ggccucuaac     1260

aaaaaccgcg gcaucaucaa aaccuucuca aacggaugcg acuacgucag caacaaaggc     1320

guagauaccg ucucugucgg caacacacug uacugcguaa acaagcaaga aggaaaaucc     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucguuuu ccccucagau     1440

gaauuugacg ccucgauauc acaagucaac gaaaagauaa aucagucccu cgccuucauc     1500

cgaaaauccg acgaacuccu ccacaacguu aacgcaggaa aguccaccac aaacaucaug     1560

auaacuacaa ucauaauagu cauuaucguc auacuccucu cccuaaucgc cguaggccug     1620

cuacucuacu gcaaagcccg cucaaccccc gucacucucu caaaagacca acucuccggc     1680

aucaauaaca ucgccuucuc aaacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  4725
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4725
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4726
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4726
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4727
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4727
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4728
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4728
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcauucu caaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4729
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4729
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4730
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4730
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcuuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4731
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4731
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauacucaa agccaacgca      120

auaacaacaa uauuaacagc cguaacauuu ugcuucgcau caggucaaaa cauaacagaa      180

gaguucuacc aauccacaug cucagcagua ucaaaaggau auuuaagugc ucuaagaaca      240

ggaugguaca cauccguaau aacaaucgaa cuaucaaaca uaaaagaaaa uaaauguaau      300

ggaacagacg ccaaaguaaa auuaaucaaa caagaacuag acaaauacaa aaacgcaguu      360

acugaauuac aauuauuaau gcaaucaaca ccggccacag gaucuggauc agcaauaugc      420

ucaggaguag cagucugcaa aguauuacac cuagaagggg aaguuaauaa aaucaaauca      480

gcauuacuau ccaccaacaa agcgguaguu ucacucucca acggcguauc ugucuuaaca      540

uucaaaguau uagaccuaaa aaacuacauu gacaaacaac uacuaccaau ccuaaacaaa      600

caaucauguu ccauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuauuagaaa uaacaagaga auuuuccguc aaugcaggag uuacuacccc ugucuccacc      720

uauaugcuaa ccaauuccga acucuuauca uuaauaaacg acaugccuau cacaaaugac      780

caaaaaaaau uaaugagcaa caacguacaa auaguacgac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu ccuagcauac guuguacaac uaccacuaua cggagucaua      900

gauaccccau gcuggaaacu ccauacaagc ccacuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacaag aacagaccga ggaugguacu gcgauaaugc cggcucaguc     1020

ucauucuuuc cgcaagccga aacuuguaaa guacaaagua acagaguauu uugugacacc     1080

augaacucaa gaacccuccc aagcgaaguc aaucuaugca acguugauau auucaauccc     1140

aaauacgacu gcaaaaucau gaccucaaaa acagacguca gcucauccgu uauaacauca     1200

cuaggagcca ucguaucuug cuauggaaaa acaaaaugca cagcaagcaa uaaaaacaga     1260

ggcauaauaa aaacauucuc aaauggaugc gacuacguau caaacaaagg agucgacaca     1320

guuuccguag gaaacacuuu auacugcgua aacaaacaag aaggaaaauc auuauacguc     1380

aaaggugaac caauaauaaa cuucuacgau ccacuuguau ucccaucaga cgaauuugac     1440

gcaucaauuu cacaaguaaa cgaaaaaaua aaccaaucac ucgcauucau aagaaaauca     1500

gaugaacuac uacauaacgu aaacgcagga aaauccacaa caaacaucau gauaacaacc     1560

aucauaaucg uaauaaucgu aauacuauua ucccuaauug caguaggauu acucuuauau     1620

ugcaaagcaa gaucaacacc aguaacccuc aguaaagacc aacuauccgg aauaaauaac     1680

aucgcauucu caaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4732
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4732
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacugc ucauccucaa agccaacgcc      120

aucaccacca uucuuaccgc cgucacauuc ugcuucgccu caggccaaaa caucaccgaa      180

gaauuuuacc aauccacuug uucagccguc ucaaaaggau accuaucagc ccuccguacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaggucaa acugauaaaa caagaacuug auaaauacaa aaacgccguc      360

acugaacucc aacuccucau gcaauccacu cccgcuacug gcucuggcuc cgccaucugc      420

ucuggcgucg ccgucuguaa aguacuccac cucgaagggg aagucaacaa aaucaaauca      480

gcccuccuua gcaccaacaa ggccgucguc ucccucucaa acggagucag cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaaacaac uccugcccau ccuaaauaaa      600

caauccugcu cuaucuccaa uaucgaaacc guuauagagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgcaggcg ucaccacccc ugugucaacc      720

uacaugcuca ccaacagcga acuacucuca cucaucaaug acaugcccau caccaacgac      780

caaaagaaac ucauguccaa caacguccaa aucguacguc aacaauccua cagcaucaug      840

ugcaucauaa aagaagaagu ccucgccuac gucguccaac uuccccucua cggcgucaua      900

gacacccccu gcuggaaacu gcauaccuca ccccuaugca ccaccaacac uaaagaaggc      960

uccaacaucu gccucacccg cacggaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aacuuguaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucua gaacgcugcc auccgaggua aaccuaugca acgucgacau cuucaauccc     1140

aaauacgacu gcaagaucau gaccucaaaa accgacguau ccuccucagu aaucaccagu     1200

cucggagcua ucgucuccug cuacggcaaa accaaaugca cggccucuaa caaaaaccgc     1260

ggcaucauca aaaccuucuc aaacggaugc gacuacguca gcaacaaagg cguagauacc     1320

gucucugucg gcaacacacu guacugcgua aacaagcaag aaggaaaauc ccucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucguuu uccccucaga ugaauuugac     1440

gccucgauau cacaagucaa cgaaaagaua aaucaguccc ucgccuucau ccgaaaaucc     1500

gacgaacucc uccacaacgu uaacgcagga aaguccacca caaacaucau gauaacuaca     1560

aucauaauag ucauuaucgu cauacuccuc ucccuaaucg ccguaggccu gcuacucuac     1620

ugcaaagccc gcucaacccc cgucacucuc ucaaaagacc aacucuccgg caucaauaac     1680

aucgccuucu caaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  4733
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4733
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4734
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4734
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4735
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4735
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4736
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4736
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgca uucucaaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4737
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4737
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4738
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4738
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcu uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4739
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4739
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauac ucaaagccaa cgcaauaaca acaauauuaa cagccguaac auuuugcuuc      240

gcaucagguc aaaacauaac agaagaguuc uaccaaucca caugcucagc aguaucaaaa      300

ggauauuuaa gugcucuaag aacaggaugg uacacauccg uaauaacaau cgaacuauca      360

aacauaaaag aaaauaaaug uaauggaaca gacgccaaag uaaaauuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguuacugaa uuacaauuau uaaugcaauc aacaccggcc      480

acaggaucug gaucagcaau augcucagga guagcagucu gcaaaguauu acaccuagaa      540

ggggaaguua auaaaaucaa aucagcauua cuauccacca acaaagcggu aguuucacuc      600

uccaacggcg uaucugucuu aacauucaaa guauuagacc uaaaaaacua cauugacaaa      660

caacuacuac caauccuaaa caaacaauca uguuccauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuauua gaaauaacaa gagaauuuuc cgucaaugca      780

ggaguuacua ccccugucuc caccuauaug cuaaccaauu ccgaacucuu aucauuaaua      840

aacgacaugc cuaucacaaa ugaccaaaaa aaauuaauga gcaacaacgu acaaauagua      900

cgacaacaau cauacucaau caugugcaua auaaaagaag aaguccuagc auacguugua      960

caacuaccac uauacggagu cauagauacc ccaugcugga aacuccauac aagcccacua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa caagaacaga ccgaggaugg     1080

uacugcgaua augccggcuc agucucauuc uuuccgcaag ccgaaacuug uaaaguacaa     1140

aguaacagag uauuuuguga caccaugaac ucaagaaccc ucccaagcga agucaaucua     1200

ugcaacguug auauauucaa ucccaaauac gacugcaaaa ucaugaccuc aaaaacagac     1260

gucagcucau ccguuauaac aucacuagga gccaucguau cuugcuaugg aaaaacaaaa     1320

ugcacagcaa gcaauaaaaa cagaggcaua auaaaaacau ucucaaaugg augcgacuac     1380

guaucaaaca aaggagucga cacaguuucc guaggaaaca cuuuauacug cguaaacaaa     1440

caagaaggaa aaucauuaua cgucaaaggu gaaccaauaa uaaacuucua cgauccacuu     1500

guauucccau cagacgaauu ugacgcauca auuucacaag uaaacgaaaa aauaaaccaa     1560

ucacucgcau ucauaagaaa aucagaugaa cuacuacaua acguaaacgc aggaaaaucc     1620

acaacaaaca ucaugauaac aaccaucaua aucguaauaa ucguaauacu auuaucccua     1680

auugcaguag gauuacucuu auauugcaaa gcaagaucaa caccaguaac ccucaguaaa     1740

gaccaacuau ccggaauaaa uaacaucgca uucucaaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4740
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4740
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cugcucaucc ucaaagccaa cgccaucacc accauucuua ccgccgucac auucugcuuc      240

gccucaggcc aaaacaucac cgaagaauuu uaccaaucca cuuguucagc cgucucaaaa      300

ggauaccuau cagcccuccg uaccggcugg uacaccucgg ucauaacaau agaacucucc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaagg ucaaacugau aaaacaagaa      420

cuugauaaau acaaaaacgc cgucacugaa cuccaacucc ucaugcaauc cacucccgcu      480

acuggcucug gcuccgccau cugcucuggc gucgccgucu guaaaguacu ccaccucgaa      540

ggggaaguca acaaaaucaa aucagcccuc cuuagcacca acaaggccgu cgucucccuc      600

ucaaacggag ucagcguccu caccuucaag guccucgacc ucaagaacua caucgacaaa      660

caacuccugc ccauccuaaa uaaacaaucc ugcucuaucu ccaauaucga aaccguuaua      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgca      780

ggcgucacca ccccuguguc aaccuacaug cucaccaaca gcgaacuacu cucacucauc      840

aaugacaugc ccaucaccaa cgaccaaaag aaacucaugu ccaacaacgu ccaaaucgua      900

cgucaacaau ccuacagcau caugugcauc auaaaagaag aaguccucgc cuacgucguc      960

caacuucccc ucuacggcgu cauagacacc cccugcugga aacugcauac cucaccccua     1020

ugcaccacca acacuaaaga aggcuccaac aucugccuca cccgcacgga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaacuug uaaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucuagaacgc ugccauccga gguaaaccua     1200

ugcaacgucg acaucuucaa ucccaaauac gacugcaaga ucaugaccuc aaaaaccgac     1260

guauccuccu caguaaucac cagucucgga gcuaucgucu ccugcuacgg caaaaccaaa     1320

ugcacggccu cuaacaaaaa ccgcggcauc aucaaaaccu ucucaaacgg augcgacuac     1380

gucagcaaca aaggcguaga uaccgucucu gucggcaaca cacuguacug cguaaacaag     1440

caagaaggaa aaucccucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

guuuuccccu cagaugaauu ugacgccucg auaucacaag ucaacgaaaa gauaaaucag     1560

ucccucgccu ucauccgaaa auccgacgaa cuccuccaca acguuaacgc aggaaagucc     1620

accacaaaca ucaugauaac uacaaucaua auagucauua ucgucauacu ccucucccua     1680

aucgccguag gccugcuacu cuacugcaaa gcccgcucaa cccccgucac ucucucaaaa     1740

gaccaacucu ccggcaucaa uaacaucgcc uucucaaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  4741
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4741
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4742
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4742
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4743
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4743
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4744
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4744
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcauucucaa     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4745
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4745
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4746
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4746
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcuuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4747
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4747
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uacucaaagc caacgcaaua acaacaauau      120

uaacagccgu aacauuuugc uucgcaucag gucaaaacau aacagaagag uucuaccaau      180

ccacaugcuc agcaguauca aaaggauauu uaagugcucu aagaacagga ugguacacau      240

ccguaauaac aaucgaacua ucaaacauaa aagaaaauaa auguaaugga acagacgcca      300

aaguaaaauu aaucaaacaa gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau      360

uauuaaugca aucaacaccg gccacaggau cuggaucagc aauaugcuca ggaguagcag      420

ucugcaaagu auuacaccua gaaggggaag uuaauaaaau caaaucagca uuacuaucca      480

ccaacaaagc gguaguuuca cucuccaacg gcguaucugu cuuaacauuc aaaguauuag      540

accuaaaaaa cuacauugac aaacaacuac uaccaauccu aaacaaacaa ucauguucca      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua uuagaaauaa      660

caagagaauu uuccgucaau gcaggaguua cuaccccugu cuccaccuau augcuaacca      720

auuccgaacu cuuaucauua auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa      780

ugagcaacaa cguacaaaua guacgacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguccu agcauacguu guacaacuac cacuauacgg agucauagau accccaugcu      900

ggaaacucca uacaagccca cuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacaagaac agaccgagga ugguacugcg auaaugccgg cucagucuca uucuuuccgc     1020

aagccgaaac uuguaaagua caaaguaaca gaguauuuug ugacaccaug aacucaagaa     1080

cccucccaag cgaagucaau cuaugcaacg uugauauauu caaucccaaa uacgacugca     1140

aaaucaugac cucaaaaaca gacgucagcu cauccguuau aacaucacua ggagccaucg     1200

uaucuugcua uggaaaaaca aaaugcacag caagcaauaa aaacagaggc auaauaaaaa     1260

cauucucaaa uggaugcgac uacguaucaa acaaaggagu cgacacaguu uccguaggaa     1320

acacuuuaua cugcguaaac aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa     1380

uaauaaacuu cuacgaucca cuuguauucc caucagacga auuugacgca ucaauuucac     1440

aaguaaacga aaaaauaaac caaucacucg cauucauaag aaaaucagau gaacuacuac     1500

auaacguaaa cgcaggaaaa uccacaacaa acaucaugau aacaaccauc auaaucguaa     1560

uaaucguaau acuauuaucc cuaauugcag uaggauuacu cuuauauugc aaagcaagau     1620

caacaccagu aacccucagu aaagaccaac uauccggaau aaauaacauc gcauucucaa     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4748
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4748
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacugcuca uccucaaagc caacgccauc accaccauuc      120

uuaccgccgu cacauucugc uucgccucag gccaaaacau caccgaagaa uuuuaccaau      180

ccacuuguuc agccgucuca aaaggauacc uaucagcccu ccguaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaacauaa aagaaaacaa augcaacggc accgacgcca      300

aggucaaacu gauaaaacaa gaacuugaua aauacaaaaa cgccgucacu gaacuccaac      360

uccucaugca auccacuccc gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg      420

ucuguaaagu acuccaccuc gaaggggaag ucaacaaaau caaaucagcc cuccuuagca      480

ccaacaaggc cgucgucucc cucucaaacg gagucagcgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aaacaacucc ugcccauccu aaauaaacaa uccugcucua      600

ucuccaauau cgaaaccguu auagaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gcaggcguca ccaccccugu gucaaccuac augcucacca      720

acagcgaacu acucucacuc aucaaugaca ugcccaucac caacgaccaa aagaaacuca      780

uguccaacaa cguccaaauc guacgucaac aauccuacag caucaugugc aucauaaaag      840

aagaaguccu cgccuacguc guccaacuuc cccucuacgg cgucauagac acccccugcu      900

ggaaacugca uaccucaccc cuaugcacca ccaacacuaa agaaggcucc aacaucugcc      960

ucacccgcac ggaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac uuguaaaguc caauccaaca gagucuucug cgacaccaug aacucuagaa     1080

cgcugccauc cgagguaaac cuaugcaacg ucgacaucuu caaucccaaa uacgacugca     1140

agaucaugac cucaaaaacc gacguauccu ccucaguaau caccagucuc ggagcuaucg     1200

ucuccugcua cggcaaaacc aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa     1260

ccuucucaaa cggaugcgac uacgucagca acaaaggcgu agauaccguc ucugucggca     1320

acacacugua cugcguaaac aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucguuuucc ccucagauga auuugacgcc ucgauaucac     1440

aagucaacga aaagauaaau cagucccucg ccuucauccg aaaauccgac gaacuccucc     1500

acaacguuaa cgcaggaaag uccaccacaa acaucaugau aacuacaauc auaauaguca     1560

uuaucgucau acuccucucc cuaaucgccg uaggccugcu acucuacugc aaagcccgcu     1620

caacccccgu cacucucuca aaagaccaac ucuccggcau caauaacauc gccuucucaa     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  4749
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4749
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4750
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4750
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4751
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4751
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4752
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4752
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgca uucucaaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4753
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4753
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4754
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4754
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcu uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4755
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4755
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauac ucaaagccaa cgcaauaaca acaauauuaa cagccguaac auuuugcuuc      240

gcaucagguc aaaacauaac agaagaguuc uaccaaucca caugcucagc aguaucaaaa      300

ggauauuuaa gugcucuaag aacaggaugg uacacauccg uaauaacaau cgaacuauca      360

aacauaaaag aaaauaaaug uaauggaaca gacgccaaag uaaaauuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguuacugaa uuacaauuau uaaugcaauc aacaccggcc      480

acaggaucug gaucagcaau augcucagga guagcagucu gcaaaguauu acaccuagaa      540

ggggaaguua auaaaaucaa aucagcauua cuauccacca acaaagcggu aguuucacuc      600

uccaacggcg uaucugucuu aacauucaaa guauuagacc uaaaaaacua cauugacaaa      660

caacuacuac caauccuaaa caaacaauca uguuccauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuauua gaaauaacaa gagaauuuuc cgucaaugca      780

ggaguuacua ccccugucuc caccuauaug cuaaccaauu ccgaacucuu aucauuaaua      840

aacgacaugc cuaucacaaa ugaccaaaaa aaauuaauga gcaacaacgu acaaauagua      900

cgacaacaau cauacucaau caugugcaua auaaaagaag aaguccuagc auacguugua      960

caacuaccac uauacggagu cauagauacc ccaugcugga aacuccauac aagcccacua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa caagaacaga ccgaggaugg     1080

uacugcgaua augccggcuc agucucauuc uuuccgcaag ccgaaacuug uaaaguacaa     1140

aguaacagag uauuuuguga caccaugaac ucaagaaccc ucccaagcga agucaaucua     1200

ugcaacguug auauauucaa ucccaaauac gacugcaaaa ucaugaccuc aaaaacagac     1260

gucagcucau ccguuauaac aucacuagga gccaucguau cuugcuaugg aaaaacaaaa     1320

ugcacagcaa gcaauaaaaa cagaggcaua auaaaaacau ucucaaaugg augcgacuac     1380

guaucaaaca aaggagucga cacaguuucc guaggaaaca cuuuauacug cguaaacaaa     1440

caagaaggaa aaucauuaua cgucaaaggu gaaccaauaa uaaacuucua cgauccacuu     1500

guauucccau cagacgaauu ugacgcauca auuucacaag uaaacgaaaa aauaaaccaa     1560

ucacucgcau ucauaagaaa aucagaugaa cuacuacaua acguaaacgc aggaaaaucc     1620

acaacaaaca ucaugauaac aaccaucaua aucguaauaa ucguaauacu auuaucccua     1680

auugcaguag gauuacucuu auauugcaaa gcaagaucaa caccaguaac ccucaguaaa     1740

gaccaacuau ccggaauaaa uaacaucgca uucucaaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4756
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4756
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cugcucaucc ucaaagccaa cgccaucacc accauucuua ccgccgucac auucugcuuc      240

gccucaggcc aaaacaucac cgaagaauuu uaccaaucca cuuguucagc cgucucaaaa      300

ggauaccuau cagcccuccg uaccggcugg uacaccucgg ucauaacaau agaacucucc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaagg ucaaacugau aaaacaagaa      420

cuugauaaau acaaaaacgc cgucacugaa cuccaacucc ucaugcaauc cacucccgcu      480

acuggcucug gcuccgccau cugcucuggc gucgccgucu guaaaguacu ccaccucgaa      540

ggggaaguca acaaaaucaa aucagcccuc cuuagcacca acaaggccgu cgucucccuc      600

ucaaacggag ucagcguccu caccuucaag guccucgacc ucaagaacua caucgacaaa      660

caacuccugc ccauccuaaa uaaacaaucc ugcucuaucu ccaauaucga aaccguuaua      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgca      780

ggcgucacca ccccuguguc aaccuacaug cucaccaaca gcgaacuacu cucacucauc      840

aaugacaugc ccaucaccaa cgaccaaaag aaacucaugu ccaacaacgu ccaaaucgua      900

cgucaacaau ccuacagcau caugugcauc auaaaagaag aaguccucgc cuacgucguc      960

caacuucccc ucuacggcgu cauagacacc cccugcugga aacugcauac cucaccccua     1020

ugcaccacca acacuaaaga aggcuccaac aucugccuca cccgcacgga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaacuug uaaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucuagaacgc ugccauccga gguaaaccua     1200

ugcaacgucg acaucuucaa ucccaaauac gacugcaaga ucaugaccuc aaaaaccgac     1260

guauccuccu caguaaucac cagucucgga gcuaucgucu ccugcuacgg caaaaccaaa     1320

ugcacggccu cuaacaaaaa ccgcggcauc aucaaaaccu ucucaaacgg augcgacuac     1380

gucagcaaca aaggcguaga uaccgucucu gucggcaaca cacuguacug cguaaacaag     1440

caagaaggaa aaucccucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

guuuuccccu cagaugaauu ugacgccucg auaucacaag ucaacgaaaa gauaaaucag     1560

ucccucgccu ucauccgaaa auccgacgaa cuccuccaca acguuaacgc aggaaagucc     1620

accacaaaca ucaugauaac uacaaucaua auagucauua ucgucauacu ccucucccua     1680

aucgccguag gccugcuacu cuacugcaaa gcccgcucaa cccccgucac ucucucaaaa     1740

gaccaacucu ccggcaucaa uaacaucgcc uucucaaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  4757
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4757
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4758
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4758
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      540

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1140

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1260

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1320

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1380

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1680

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4759
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4759
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4760
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4760
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      480

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      540

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      600

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      720

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      780

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      840

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua      900

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca      960

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc     1020

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1080

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1140

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1200

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1260

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1320

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1380

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1440

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1500

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1560

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1620

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu cuacaccggu gacccugagc     1680

aaggaccagc ucuccggcau aaacaauauc gcauucucaa acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4761
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4761
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4762
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4762
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      480

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      540

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      600

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      720

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      780

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      840

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      900

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu      960

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga     1020

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1080

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1140

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1200

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1260

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1320

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1380

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1440

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1500

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1620

cugaucgccg ugggccuccu gcuguauugc aaagccagau ccacaccugu gacccuuagc     1680

aaggaccagc ucucugggau uaacaauauc gcuuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4763
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4763
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuucuaa uacucaaagc caacgcaaua acaacaauau uaacagccgu aacauuuugc      180

uucgcaucag gucaaaacau aacagaagag uucuaccaau ccacaugcuc agcaguauca      240

aaaggauauu uaagugcucu aagaacagga ugguacacau ccguaauaac aaucgaacua      300

ucaaacauaa aagaaaauaa auguaaugga acagacgcca aaguaaaauu aaucaaacaa      360

gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau uauuaaugca aucaacaccg      420

gccacaggau cuggaucagc aauaugcuca ggaguagcag ucugcaaagu auuacaccua      480

gaaggggaag uuaauaaaau caaaucagca uuacuaucca ccaacaaagc gguaguuuca      540

cucuccaacg gcguaucugu cuuaacauuc aaaguauuag accuaaaaaa cuacauugac      600

aaacaacuac uaccaauccu aaacaaacaa ucauguucca uaagcaauau agaaacagua      660

auagaauuuc aacaaaaaaa caacagacua uuagaaauaa caagagaauu uuccgucaau      720

gcaggaguua cuaccccugu cuccaccuau augcuaacca auuccgaacu cuuaucauua      780

auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa ugagcaacaa cguacaaaua      840

guacgacaac aaucauacuc aaucaugugc auaauaaaag aagaaguccu agcauacguu      900

guacaacuac cacuauacgg agucauagau accccaugcu ggaaacucca uacaagccca      960

cuaugcacua caaacacaaa agaaggcucu aauauauguc uaacaagaac agaccgagga     1020

ugguacugcg auaaugccgg cucagucuca uucuuuccgc aagccgaaac uuguaaagua     1080

caaaguaaca gaguauuuug ugacaccaug aacucaagaa cccucccaag cgaagucaau     1140

cuaugcaacg uugauauauu caaucccaaa uacgacugca aaaucaugac cucaaaaaca     1200

gacgucagcu cauccguuau aacaucacua ggagccaucg uaucuugcua uggaaaaaca     1260

aaaugcacag caagcaauaa aaacagaggc auaauaaaaa cauucucaaa uggaugcgac     1320

uacguaucaa acaaaggagu cgacacaguu uccguaggaa acacuuuaua cugcguaaac     1380

aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa uaauaaacuu cuacgaucca     1440

cuuguauucc caucagacga auuugacgca ucaauuucac aaguaaacga aaaaauaaac     1500

caaucacucg cauucauaag aaaaucagau gaacuacuac auaacguaaa cgcaggaaaa     1560

uccacaacaa acaucaugau aacaaccauc auaaucguaa uaaucguaau acuauuaucc     1620

cuaauugcag uaggauuacu cuuauauugc aaagcaagau caacaccagu aacccucagu     1680

aaagaccaac uauccggaau aaauaacauc gcauucucaa acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4764
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4764
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacugcuca uccucaaagc caacgccauc accaccauuc uuaccgccgu cacauucugc      180

uucgccucag gccaaaacau caccgaagaa uuuuaccaau ccacuuguuc agccgucuca      240

aaaggauacc uaucagcccu ccguaccggc ugguacaccu cggucauaac aauagaacuc      300

uccaacauaa aagaaaacaa augcaacggc accgacgcca aggucaaacu gauaaaacaa      360

gaacuugaua aauacaaaaa cgccgucacu gaacuccaac uccucaugca auccacuccc      420

gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg ucuguaaagu acuccaccuc      480

gaaggggaag ucaacaaaau caaaucagcc cuccuuagca ccaacaaggc cgucgucucc      540

cucucaaacg gagucagcgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aaacaacucc ugcccauccu aaauaaacaa uccugcucua ucuccaauau cgaaaccguu      660

auagaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      720

gcaggcguca ccaccccugu gucaaccuac augcucacca acagcgaacu acucucacuc      780

aucaaugaca ugcccaucac caacgaccaa aagaaacuca uguccaacaa cguccaaauc      840

guacgucaac aauccuacag caucaugugc aucauaaaag aagaaguccu cgccuacguc      900

guccaacuuc cccucuacgg cgucauagac acccccugcu ggaaacugca uaccucaccc      960

cuaugcacca ccaacacuaa agaaggcucc aacaucugcc ucacccgcac ggaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac uuguaaaguc     1080

caauccaaca gagucuucug cgacaccaug aacucuagaa cgcugccauc cgagguaaac     1140

cuaugcaacg ucgacaucuu caaucccaaa uacgacugca agaucaugac cucaaaaacc     1200

gacguauccu ccucaguaau caccagucuc ggagcuaucg ucuccugcua cggcaaaacc     1260

aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa ccuucucaaa cggaugcgac     1320

uacgucagca acaaaggcgu agauaccguc ucugucggca acacacugua cugcguaaac     1380

aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1440

cucguuuucc ccucagauga auuugacgcc ucgauaucac aagucaacga aaagauaaau     1500

cagucccucg ccuucauccg aaaauccgac gaacuccucc acaacguuaa cgcaggaaag     1560

uccaccacaa acaucaugau aacuacaauc auaauaguca uuaucgucau acuccucucc     1620

cuaaucgccg uaggccugcu acucuacugc aaagcccgcu caacccccgu cacucucuca     1680

aaagaccaac ucuccggcau caauaacauc gccuucucaa acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  4765
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4765
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4766
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4766
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4767
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4767
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4768
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4768
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcauucuc aaacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4769
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4769
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4770
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4770
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcuuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4771
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4771
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauacucaaa      120

gccaacgcaa uaacaacaau auuaacagcc guaacauuuu gcuucgcauc aggucaaaac      180

auaacagaag aguucuacca auccacaugc ucagcaguau caaaaggaua uuuaagugcu      240

cuaagaacag gaugguacac auccguaaua acaaucgaac uaucaaacau aaaagaaaau      300

aaauguaaug gaacagacgc caaaguaaaa uuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguua cugaauuaca auuauuaaug caaucaacac cggccacagg aucuggauca      420

gcaauaugcu caggaguagc agucugcaaa guauuacacc uagaagggga aguuaauaaa      480

aucaaaucag cauuacuauc caccaacaaa gcgguaguuu cacucuccaa cggcguaucu      540

gucuuaacau ucaaaguauu agaccuaaaa aacuacauug acaaacaacu acuaccaauc      600

cuaaacaaac aaucauguuc cauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uauuagaaau aacaagagaa uuuuccguca augcaggagu uacuaccccu      720

gucuccaccu auaugcuaac caauuccgaa cucuuaucau uaauaaacga caugccuauc      780

acaaaugacc aaaaaaaauu aaugagcaac aacguacaaa uaguacgaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguc cuagcauacg uuguacaacu accacuauac      900

ggagucauag auaccccaug cuggaaacuc cauacaagcc cacuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacaaga acagaccgag gaugguacug cgauaaugcc     1020

ggcucagucu cauucuuucc gcaagccgaa acuuguaaag uacaaaguaa cagaguauuu     1080

ugugacacca ugaacucaag aacccuccca agcgaaguca aucuaugcaa cguugauaua     1140

uucaauccca aauacgacug caaaaucaug accucaaaaa cagacgucag cucauccguu     1200

auaacaucac uaggagccau cguaucuugc uauggaaaaa caaaaugcac agcaagcaau     1260

aaaaacagag gcauaauaaa aacauucuca aauggaugcg acuacguauc aaacaaagga     1320

gucgacacag uuuccguagg aaacacuuua uacugcguaa acaaacaaga aggaaaauca     1380

uuauacguca aaggugaacc aauaauaaac uucuacgauc cacuuguauu cccaucagac     1440

gaauuugacg caucaauuuc acaaguaaac gaaaaaauaa accaaucacu cgcauucaua     1500

agaaaaucag augaacuacu acauaacgua aacgcaggaa aauccacaac aaacaucaug     1560

auaacaacca ucauaaucgu aauaaucgua auacuauuau cccuaauugc aguaggauua     1620

cucuuauauu gcaaagcaag aucaacacca guaacccuca guaaagacca acuauccgga     1680

auaaauaaca ucgcauucuc aaacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4772
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4772
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacugcu cauccucaaa      120

gccaacgcca ucaccaccau ucuuaccgcc gucacauucu gcuucgccuc aggccaaaac      180

aucaccgaag aauuuuacca auccacuugu ucagccgucu caaaaggaua ccuaucagcc      240

cuccguaccg gcugguacac cucggucaua acaauagaac ucuccaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaggucaaa cugauaaaac aagaacuuga uaaauacaaa      360

aacgccguca cugaacucca acuccucaug caauccacuc ccgcuacugg cucuggcucc      420

gccaucugcu cuggcgucgc cgucuguaaa guacuccacc ucgaagggga agucaacaaa      480

aucaaaucag cccuccuuag caccaacaag gccgucgucu cccucucaaa cggagucagc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaaacaacu ccugcccauc      600

cuaaauaaac aauccugcuc uaucuccaau aucgaaaccg uuauagaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccaccccu      720

gugucaaccu acaugcucac caacagcgaa cuacucucac ucaucaauga caugcccauc      780

accaacgacc aaaagaaacu cauguccaac aacguccaaa ucguacguca acaauccuac      840

agcaucaugu gcaucauaaa agaagaaguc cucgccuacg ucguccaacu uccccucuac      900

ggcgucauag acacccccug cuggaaacug cauaccucac cccuaugcac caccaacacu      960

aaagaaggcu ccaacaucug ccucacccgc acggaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa acuuguaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucuag aacgcugcca uccgagguaa accuaugcaa cgucgacauc     1140

uucaauccca aauacgacug caagaucaug accucaaaaa ccgacguauc cuccucagua     1200

aucaccaguc ucggagcuau cgucuccugc uacggcaaaa ccaaaugcac ggccucuaac     1260

aaaaaccgcg gcaucaucaa aaccuucuca aacggaugcg acuacgucag caacaaaggc     1320

guagauaccg ucucugucgg caacacacug uacugcguaa acaagcaaga aggaaaaucc     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucguuuu ccccucagau     1440

gaauuugacg ccucgauauc acaagucaac gaaaagauaa aucagucccu cgccuucauc     1500

cgaaaauccg acgaacuccu ccacaacguu aacgcaggaa aguccaccac aaacaucaug     1560

auaacuacaa ucauaauagu cauuaucguc auacuccucu cccuaaucgc cguaggccug     1620

cuacucuacu gcaaagcccg cucaaccccc gucacucucu caaaagacca acucuccggc     1680

aucaauaaca ucgccuucuc aaacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  4773
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4773
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4774
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4774
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4775
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4775
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4776
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4776
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcauucuc aaacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4777
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4777
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4778
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4778
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcuuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4779
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4779
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauacucaaa gccaacgcaa uaacaacaau auuaacagcc      120

guaacauuuu gcuucgcauc aggucaaaac auaacagaag aguucuacca auccacaugc      180

ucagcaguau caaaaggaua uuuaagugcu cuaagaacag gaugguacac auccguaaua      240

acaaucgaac uaucaaacau aaaagaaaau aaauguaaug gaacagacgc caaaguaaaa      300

uuaaucaaac aagaacuaga caaauacaaa aacgcaguua cugaauuaca auuauuaaug      360

caaucaacac cggccacagg aucuggauca gcaauaugcu caggaguagc agucugcaaa      420

guauuacacc uagaagggga aguuaauaaa aucaaaucag cauuacuauc caccaacaaa      480

gcgguaguuu cacucuccaa cggcguaucu gucuuaacau ucaaaguauu agaccuaaaa      540

aacuacauug acaaacaacu acuaccaauc cuaaacaaac aaucauguuc cauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uauuagaaau aacaagagaa      660

uuuuccguca augcaggagu uacuaccccu gucuccaccu auaugcuaac caauuccgaa      720

cucuuaucau uaauaaacga caugccuauc acaaaugacc aaaaaaaauu aaugagcaac      780

aacguacaaa uaguacgaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguc      840

cuagcauacg uuguacaacu accacuauac ggagucauag auaccccaug cuggaaacuc      900

cauacaagcc cacuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacaaga      960

acagaccgag gaugguacug cgauaaugcc ggcucagucu cauucuuucc gcaagccgaa     1020

acuuguaaag uacaaaguaa cagaguauuu ugugacacca ugaacucaag aacccuccca     1080

agcgaaguca aucuaugcaa cguugauaua uucaauccca aauacgacug caaaaucaug     1140

accucaaaaa cagacgucag cucauccguu auaacaucac uaggagccau cguaucuugc     1200

uauggaaaaa caaaaugcac agcaagcaau aaaaacagag gcauaauaaa aacauucuca     1260

aauggaugcg acuacguauc aaacaaagga gucgacacag uuuccguagg aaacacuuua     1320

uacugcguaa acaaacaaga aggaaaauca uuauacguca aaggugaacc aauaauaaac     1380

uucuacgauc cacuuguauu cccaucagac gaauuugacg caucaauuuc acaaguaaac     1440

gaaaaaauaa accaaucacu cgcauucaua agaaaaucag augaacuacu acauaacgua     1500

aacgcaggaa aauccacaac aaacaucaug auaacaacca ucauaaucgu aauaaucgua     1560

auacuauuau cccuaauugc aguaggauua cucuuauauu gcaaagcaag aucaacacca     1620

guaacccuca guaaagacca acuauccgga auaaauaaca ucgcauucuc aaacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4780
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4780
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacugcu cauccucaaa gccaacgcca ucaccaccau ucuuaccgcc      120

gucacauucu gcuucgccuc aggccaaaac aucaccgaag aauuuuacca auccacuugu      180

ucagccgucu caaaaggaua ccuaucagcc cuccguaccg gcugguacac cucggucaua      240

acaauagaac ucuccaacau aaaagaaaac aaaugcaacg gcaccgacgc caaggucaaa      300

cugauaaaac aagaacuuga uaaauacaaa aacgccguca cugaacucca acuccucaug      360

caauccacuc ccgcuacugg cucuggcucc gccaucugcu cuggcgucgc cgucuguaaa      420

guacuccacc ucgaagggga agucaacaaa aucaaaucag cccuccuuag caccaacaag      480

gccgucgucu cccucucaaa cggagucagc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaaacaacu ccugcccauc cuaaauaaac aauccugcuc uaucuccaau      600

aucgaaaccg uuauagaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgcaggcgu caccaccccu gugucaaccu acaugcucac caacagcgaa      720

cuacucucac ucaucaauga caugcccauc accaacgacc aaaagaaacu cauguccaac      780

aacguccaaa ucguacguca acaauccuac agcaucaugu gcaucauaaa agaagaaguc      840

cucgccuacg ucguccaacu uccccucuac ggcgucauag acacccccug cuggaaacug      900

cauaccucac cccuaugcac caccaacacu aaagaaggcu ccaacaucug ccucacccgc      960

acggaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

acuuguaaag uccaauccaa cagagucuuc ugcgacacca ugaacucuag aacgcugcca     1080

uccgagguaa accuaugcaa cgucgacauc uucaauccca aauacgacug caagaucaug     1140

accucaaaaa ccgacguauc cuccucagua aucaccaguc ucggagcuau cgucuccugc     1200

uacggcaaaa ccaaaugcac ggccucuaac aaaaaccgcg gcaucaucaa aaccuucuca     1260

aacggaugcg acuacgucag caacaaaggc guagauaccg ucucugucgg caacacacug     1320

uacugcguaa acaagcaaga aggaaaaucc cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucguuuu ccccucagau gaauuugacg ccucgauauc acaagucaac     1440

gaaaagauaa aucagucccu cgccuucauc cgaaaauccg acgaacuccu ccacaacguu     1500

aacgcaggaa aguccaccac aaacaucaug auaacuacaa ucauaauagu cauuaucguc     1560

auacuccucu cccuaaucgc cguaggccug cuacucuacu gcaaagcccg cucaaccccc     1620

gucacucucu caaaagacca acucuccggc aucaauaaca ucgccuucuc aaacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  4781
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4781
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4782
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4782
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4783
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4783
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4784
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4784
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcau ucucaaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4785
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4785
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4786
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4786
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcuu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4787
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4787
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauacu caaagccaac gcaauaacaa caauauuaac agccguaaca      180

uuuugcuucg caucagguca aaacauaaca gaagaguucu accaauccac augcucagca      240

guaucaaaag gauauuuaag ugcucuaaga acaggauggu acacauccgu aauaacaauc      300

gaacuaucaa acauaaaaga aaauaaaugu aauggaacag acgccaaagu aaaauuaauc      360

aaacaagaac uagacaaaua caaaaacgca guuacugaau uacaauuauu aaugcaauca      420

acaccggcca caggaucugg aucagcaaua ugcucaggag uagcagucug caaaguauua      480

caccuagaag gggaaguuaa uaaaaucaaa ucagcauuac uauccaccaa caaagcggua      540

guuucacucu ccaacggcgu aucugucuua acauucaaag uauuagaccu aaaaaacuac      600

auugacaaac aacuacuacc aauccuaaac aaacaaucau guuccauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuauuag aaauaacaag agaauuuucc      720

gucaaugcag gaguuacuac cccugucucc accuauaugc uaaccaauuc cgaacucuua      780

ucauuaauaa acgacaugcc uaucacaaau gaccaaaaaa aauuaaugag caacaacgua      840

caaauaguac gacaacaauc auacucaauc augugcauaa uaaaagaaga aguccuagca      900

uacguuguac aacuaccacu auacggaguc auagauaccc caugcuggaa acuccauaca      960

agcccacuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac aagaacagac     1020

cgaggauggu acugcgauaa ugccggcuca gucucauucu uuccgcaagc cgaaacuugu     1080

aaaguacaaa guaacagagu auuuugugac accaugaacu caagaacccu cccaagcgaa     1140

gucaaucuau gcaacguuga uauauucaau cccaaauacg acugcaaaau caugaccuca     1200

aaaacagacg ucagcucauc cguuauaaca ucacuaggag ccaucguauc uugcuaugga     1260

aaaacaaaau gcacagcaag caauaaaaac agaggcauaa uaaaaacauu cucaaaugga     1320

ugcgacuacg uaucaaacaa aggagucgac acaguuuccg uaggaaacac uuuauacugc     1380

guaaacaaac aagaaggaaa aucauuauac gucaaaggug aaccaauaau aaacuucuac     1440

gauccacuug uauucccauc agacgaauuu gacgcaucaa uuucacaagu aaacgaaaaa     1500

auaaaccaau cacucgcauu cauaagaaaa ucagaugaac uacuacauaa cguaaacgca     1560

ggaaaaucca caacaaacau caugauaaca accaucauaa ucguaauaau cguaauacua     1620

uuaucccuaa uugcaguagg auuacucuua uauugcaaag caagaucaac accaguaacc     1680

cucaguaaag accaacuauc cggaauaaau aacaucgcau ucucaaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4788
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4788
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac ugcucauccu caaagccaac gccaucacca ccauucuuac cgccgucaca      180

uucugcuucg ccucaggcca aaacaucacc gaagaauuuu accaauccac uuguucagcc      240

gucucaaaag gauaccuauc agcccuccgu accggcuggu acaccucggu cauaacaaua      300

gaacucucca acauaaaaga aaacaaaugc aacggcaccg acgccaaggu caaacugaua      360

aaacaagaac uugauaaaua caaaaacgcc gucacugaac uccaacuccu caugcaaucc      420

acucccgcua cuggcucugg cuccgccauc ugcucuggcg ucgccgucug uaaaguacuc      480

caccucgaag gggaagucaa caaaaucaaa ucagcccucc uuagcaccaa caaggccguc      540

gucucccucu caaacggagu cagcguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaaac aacuccugcc cauccuaaau aaacaauccu gcucuaucuc caauaucgaa      660

accguuauag aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgcag gcgucaccac cccuguguca accuacaugc ucaccaacag cgaacuacuc      780

ucacucauca augacaugcc caucaccaac gaccaaaaga aacucauguc caacaacguc      840

caaaucguac gucaacaauc cuacagcauc augugcauca uaaaagaaga aguccucgcc      900

uacgucgucc aacuuccccu cuacggcguc auagacaccc ccugcuggaa acugcauacc      960

ucaccccuau gcaccaccaa cacuaaagaa ggcuccaaca ucugccucac ccgcacggac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaacuugu     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cuagaacgcu gccauccgag     1140

guaaaccuau gcaacgucga caucuucaau cccaaauacg acugcaagau caugaccuca     1200

aaaaccgacg uauccuccuc aguaaucacc agucucggag cuaucgucuc cugcuacggc     1260

aaaaccaaau gcacggccuc uaacaaaaac cgcggcauca ucaaaaccuu cucaaacgga     1320

ugcgacuacg ucagcaacaa aggcguagau accgucucug ucggcaacac acuguacugc     1380

guaaacaagc aagaaggaaa aucccucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg uuuuccccuc agaugaauuu gacgccucga uaucacaagu caacgaaaag     1500

auaaaucagu cccucgccuu cauccgaaaa uccgacgaac uccuccacaa cguuaacgca     1560

ggaaagucca ccacaaacau caugauaacu acaaucauaa uagucauuau cgucauacuc     1620

cucucccuaa ucgccguagg ccugcuacuc uacugcaaag cccgcucaac ccccgucacu     1680

cucucaaaag accaacucuc cggcaucaau aacaucgccu ucucaaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  4789
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4789
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4790
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4790
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4791
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4791
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4792
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4792
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcauucu caaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4793
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4793
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4794
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4794
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcuuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4795
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4795
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauacucaa agccaacgca      120

auaacaacaa uauuaacagc cguaacauuu ugcuucgcau caggucaaaa cauaacagaa      180

gaguucuacc aauccacaug cucagcagua ucaaaaggau auuuaagugc ucuaagaaca      240

ggaugguaca cauccguaau aacaaucgaa cuaucaaaca uaaaagaaaa uaaauguaau      300

ggaacagacg ccaaaguaaa auuaaucaaa caagaacuag acaaauacaa aaacgcaguu      360

acugaauuac aauuauuaau gcaaucaaca ccggccacag gaucuggauc agcaauaugc      420

ucaggaguag cagucugcaa aguauuacac cuagaagggg aaguuaauaa aaucaaauca      480

gcauuacuau ccaccaacaa agcgguaguu ucacucucca acggcguauc ugucuuaaca      540

uucaaaguau uagaccuaaa aaacuacauu gacaaacaac uacuaccaau ccuaaacaaa      600

caaucauguu ccauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuauuagaaa uaacaagaga auuuuccguc aaugcaggag uuacuacccc ugucuccacc      720

uauaugcuaa ccaauuccga acucuuauca uuaauaaacg acaugccuau cacaaaugac      780

caaaaaaaau uaaugagcaa caacguacaa auaguacgac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu ccuagcauac guuguacaac uaccacuaua cggagucaua      900

gauaccccau gcuggaaacu ccauacaagc ccacuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacaag aacagaccga ggaugguacu gcgauaaugc cggcucaguc     1020

ucauucuuuc cgcaagccga aacuuguaaa guacaaagua acagaguauu uugugacacc     1080

augaacucaa gaacccuccc aagcgaaguc aaucuaugca acguugauau auucaauccc     1140

aaauacgacu gcaaaaucau gaccucaaaa acagacguca gcucauccgu uauaacauca     1200

cuaggagcca ucguaucuug cuauggaaaa acaaaaugca cagcaagcaa uaaaaacaga     1260

ggcauaauaa aaacauucuc aaauggaugc gacuacguau caaacaaagg agucgacaca     1320

guuuccguag gaaacacuuu auacugcgua aacaaacaag aaggaaaauc auuauacguc     1380

aaaggugaac caauaauaaa cuucuacgau ccacuuguau ucccaucaga cgaauuugac     1440

gcaucaauuu cacaaguaaa cgaaaaaaua aaccaaucac ucgcauucau aagaaaauca     1500

gaugaacuac uacauaacgu aaacgcagga aaauccacaa caaacaucau gauaacaacc     1560

aucauaaucg uaauaaucgu aauacuauua ucccuaauug caguaggauu acucuuauau     1620

ugcaaagcaa gaucaacacc aguaacccuc aguaaagacc aacuauccgg aauaaauaac     1680

aucgcauucu caaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4796
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4796
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacugc ucauccucaa agccaacgcc      120

aucaccacca uucuuaccgc cgucacauuc ugcuucgccu caggccaaaa caucaccgaa      180

gaauuuuacc aauccacuug uucagccguc ucaaaaggau accuaucagc ccuccguacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaggucaa acugauaaaa caagaacuug auaaauacaa aaacgccguc      360

acugaacucc aacuccucau gcaauccacu cccgcuacug gcucuggcuc cgccaucugc      420

ucuggcgucg ccgucuguaa aguacuccac cucgaagggg aagucaacaa aaucaaauca      480

gcccuccuua gcaccaacaa ggccgucguc ucccucucaa acggagucag cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaaacaac uccugcccau ccuaaauaaa      600

caauccugcu cuaucuccaa uaucgaaacc guuauagagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgcaggcg ucaccacccc ugugucaacc      720

uacaugcuca ccaacagcga acuacucuca cucaucaaug acaugcccau caccaacgac      780

caaaagaaac ucauguccaa caacguccaa aucguacguc aacaauccua cagcaucaug      840

ugcaucauaa aagaagaagu ccucgccuac gucguccaac uuccccucua cggcgucaua      900

gacacccccu gcuggaaacu gcauaccuca ccccuaugca ccaccaacac uaaagaaggc      960

uccaacaucu gccucacccg cacggaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aacuuguaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucua gaacgcugcc auccgaggua aaccuaugca acgucgacau cuucaauccc     1140

aaauacgacu gcaagaucau gaccucaaaa accgacguau ccuccucagu aaucaccagu     1200

cucggagcua ucgucuccug cuacggcaaa accaaaugca cggccucuaa caaaaaccgc     1260

ggcaucauca aaaccuucuc aaacggaugc gacuacguca gcaacaaagg cguagauacc     1320

gucucugucg gcaacacacu guacugcgua aacaagcaag aaggaaaauc ccucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucguuu uccccucaga ugaauuugac     1440

gccucgauau cacaagucaa cgaaaagaua aaucaguccc ucgccuucau ccgaaaaucc     1500

gacgaacucc uccacaacgu uaacgcagga aaguccacca caaacaucau gauaacuaca     1560

aucauaauag ucauuaucgu cauacuccuc ucccuaaucg ccguaggccu gcuacucuac     1620

ugcaaagccc gcucaacccc cgucacucuc ucaaaagacc aacucuccgg caucaauaac     1680

aucgccuucu caaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  4797
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4797
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4798
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4798
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4799
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4799
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4800
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4800
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcauucu caaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4801
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4801
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4802
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4802
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcuuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4803
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4803
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauacucaa agccaacgca      120

auaacaacaa uauuaacagc cguaacauuu ugcuucgcau caggucaaaa cauaacagaa      180

gaguucuacc aauccacaug cucagcagua ucaaaaggau auuuaagugc ucuaagaaca      240

ggaugguaca cauccguaau aacaaucgaa cuaucaaaca uaaaagaaaa uaaauguaau      300

ggaacagacg ccaaaguaaa auuaaucaaa caagaacuag acaaauacaa aaacgcaguu      360

acugaauuac aauuauuaau gcaaucaaca ccggccacag gaucuggauc agcaauaugc      420

ucaggaguag cagucugcaa aguauuacac cuagaagggg aaguuaauaa aaucaaauca      480

gcauuacuau ccaccaacaa agcgguaguu ucacucucca acggcguauc ugucuuaaca      540

uucaaaguau uagaccuaaa aaacuacauu gacaaacaac uacuaccaau ccuaaacaaa      600

caaucauguu ccauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuauuagaaa uaacaagaga auuuuccguc aaugcaggag uuacuacccc ugucuccacc      720

uauaugcuaa ccaauuccga acucuuauca uuaauaaacg acaugccuau cacaaaugac      780

caaaaaaaau uaaugagcaa caacguacaa auaguacgac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu ccuagcauac guuguacaac uaccacuaua cggagucaua      900

gauaccccau gcuggaaacu ccauacaagc ccacuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacaag aacagaccga ggaugguacu gcgauaaugc cggcucaguc     1020

ucauucuuuc cgcaagccga aacuuguaaa guacaaagua acagaguauu uugugacacc     1080

augaacucaa gaacccuccc aagcgaaguc aaucuaugca acguugauau auucaauccc     1140

aaauacgacu gcaaaaucau gaccucaaaa acagacguca gcucauccgu uauaacauca     1200

cuaggagcca ucguaucuug cuauggaaaa acaaaaugca cagcaagcaa uaaaaacaga     1260

ggcauaauaa aaacauucuc aaauggaugc gacuacguau caaacaaagg agucgacaca     1320

guuuccguag gaaacacuuu auacugcgua aacaaacaag aaggaaaauc auuauacguc     1380

aaaggugaac caauaauaaa cuucuacgau ccacuuguau ucccaucaga cgaauuugac     1440

gcaucaauuu cacaaguaaa cgaaaaaaua aaccaaucac ucgcauucau aagaaaauca     1500

gaugaacuac uacauaacgu aaacgcagga aaauccacaa caaacaucau gauaacaacc     1560

aucauaaucg uaauaaucgu aauacuauua ucccuaauug caguaggauu acucuuauau     1620

ugcaaagcaa gaucaacacc aguaacccuc aguaaagacc aacuauccgg aauaaauaac     1680

aucgcauucu caaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4804
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4804
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacugc ucauccucaa agccaacgcc      120

aucaccacca uucuuaccgc cgucacauuc ugcuucgccu caggccaaaa caucaccgaa      180

gaauuuuacc aauccacuug uucagccguc ucaaaaggau accuaucagc ccuccguacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaggucaa acugauaaaa caagaacuug auaaauacaa aaacgccguc      360

acugaacucc aacuccucau gcaauccacu cccgcuacug gcucuggcuc cgccaucugc      420

ucuggcgucg ccgucuguaa aguacuccac cucgaagggg aagucaacaa aaucaaauca      480

gcccuccuua gcaccaacaa ggccgucguc ucccucucaa acggagucag cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaaacaac uccugcccau ccuaaauaaa      600

caauccugcu cuaucuccaa uaucgaaacc guuauagagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgcaggcg ucaccacccc ugugucaacc      720

uacaugcuca ccaacagcga acuacucuca cucaucaaug acaugcccau caccaacgac      780

caaaagaaac ucauguccaa caacguccaa aucguacguc aacaauccua cagcaucaug      840

ugcaucauaa aagaagaagu ccucgccuac gucguccaac uuccccucua cggcgucaua      900

gacacccccu gcuggaaacu gcauaccuca ccccuaugca ccaccaacac uaaagaaggc      960

uccaacaucu gccucacccg cacggaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aacuuguaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucua gaacgcugcc auccgaggua aaccuaugca acgucgacau cuucaauccc     1140

aaauacgacu gcaagaucau gaccucaaaa accgacguau ccuccucagu aaucaccagu     1200

cucggagcua ucgucuccug cuacggcaaa accaaaugca cggccucuaa caaaaaccgc     1260

ggcaucauca aaaccuucuc aaacggaugc gacuacguca gcaacaaagg cguagauacc     1320

gucucugucg gcaacacacu guacugcgua aacaagcaag aaggaaaauc ccucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucguuu uccccucaga ugaauuugac     1440

gccucgauau cacaagucaa cgaaaagaua aaucaguccc ucgccuucau ccgaaaaucc     1500

gacgaacucc uccacaacgu uaacgcagga aaguccacca caaacaucau gauaacuaca     1560

aucauaauag ucauuaucgu cauacuccuc ucccuaaucg ccguaggccu gcuacucuac     1620

ugcaaagccc gcucaacccc cgucacucuc ucaaaagacc aacucuccgg caucaauaac     1680

aucgccuucu caaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  4805
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4805
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4806
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4806
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4807
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4807
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4808
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4808
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcauucu caaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4809
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4809
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4810
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4810
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcuuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4811
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4811
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauacucaa agccaacgca      120

auaacaacaa uauuaacagc cguaacauuu ugcuucgcau caggucaaaa cauaacagaa      180

gaguucuacc aauccacaug cucagcagua ucaaaaggau auuuaagugc ucuaagaaca      240

ggaugguaca cauccguaau aacaaucgaa cuaucaaaca uaaaagaaaa uaaauguaau      300

ggaacagacg ccaaaguaaa auuaaucaaa caagaacuag acaaauacaa aaacgcaguu      360

acugaauuac aauuauuaau gcaaucaaca ccggccacag gaucuggauc agcaauaugc      420

ucaggaguag cagucugcaa aguauuacac cuagaagggg aaguuaauaa aaucaaauca      480

gcauuacuau ccaccaacaa agcgguaguu ucacucucca acggcguauc ugucuuaaca      540

uucaaaguau uagaccuaaa aaacuacauu gacaaacaac uacuaccaau ccuaaacaaa      600

caaucauguu ccauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuauuagaaa uaacaagaga auuuuccguc aaugcaggag uuacuacccc ugucuccacc      720

uauaugcuaa ccaauuccga acucuuauca uuaauaaacg acaugccuau cacaaaugac      780

caaaaaaaau uaaugagcaa caacguacaa auaguacgac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu ccuagcauac guuguacaac uaccacuaua cggagucaua      900

gauaccccau gcuggaaacu ccauacaagc ccacuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacaag aacagaccga ggaugguacu gcgauaaugc cggcucaguc     1020

ucauucuuuc cgcaagccga aacuuguaaa guacaaagua acagaguauu uugugacacc     1080

augaacucaa gaacccuccc aagcgaaguc aaucuaugca acguugauau auucaauccc     1140

aaauacgacu gcaaaaucau gaccucaaaa acagacguca gcucauccgu uauaacauca     1200

cuaggagcca ucguaucuug cuauggaaaa acaaaaugca cagcaagcaa uaaaaacaga     1260

ggcauaauaa aaacauucuc aaauggaugc gacuacguau caaacaaagg agucgacaca     1320

guuuccguag gaaacacuuu auacugcgua aacaaacaag aaggaaaauc auuauacguc     1380

aaaggugaac caauaauaaa cuucuacgau ccacuuguau ucccaucaga cgaauuugac     1440

gcaucaauuu cacaaguaaa cgaaaaaaua aaccaaucac ucgcauucau aagaaaauca     1500

gaugaacuac uacauaacgu aaacgcagga aaauccacaa caaacaucau gauaacaacc     1560

aucauaaucg uaauaaucgu aauacuauua ucccuaauug caguaggauu acucuuauau     1620

ugcaaagcaa gaucaacacc aguaacccuc aguaaagacc aacuauccgg aauaaauaac     1680

aucgcauucu caaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4812
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4812
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacugc ucauccucaa agccaacgcc      120

aucaccacca uucuuaccgc cgucacauuc ugcuucgccu caggccaaaa caucaccgaa      180

gaauuuuacc aauccacuug uucagccguc ucaaaaggau accuaucagc ccuccguacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaggucaa acugauaaaa caagaacuug auaaauacaa aaacgccguc      360

acugaacucc aacuccucau gcaauccacu cccgcuacug gcucuggcuc cgccaucugc      420

ucuggcgucg ccgucuguaa aguacuccac cucgaagggg aagucaacaa aaucaaauca      480

gcccuccuua gcaccaacaa ggccgucguc ucccucucaa acggagucag cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaaacaac uccugcccau ccuaaauaaa      600

caauccugcu cuaucuccaa uaucgaaacc guuauagagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgcaggcg ucaccacccc ugugucaacc      720

uacaugcuca ccaacagcga acuacucuca cucaucaaug acaugcccau caccaacgac      780

caaaagaaac ucauguccaa caacguccaa aucguacguc aacaauccua cagcaucaug      840

ugcaucauaa aagaagaagu ccucgccuac gucguccaac uuccccucua cggcgucaua      900

gacacccccu gcuggaaacu gcauaccuca ccccuaugca ccaccaacac uaaagaaggc      960

uccaacaucu gccucacccg cacggaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aacuuguaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucua gaacgcugcc auccgaggua aaccuaugca acgucgacau cuucaauccc     1140

aaauacgacu gcaagaucau gaccucaaaa accgacguau ccuccucagu aaucaccagu     1200

cucggagcua ucgucuccug cuacggcaaa accaaaugca cggccucuaa caaaaaccgc     1260

ggcaucauca aaaccuucuc aaacggaugc gacuacguca gcaacaaagg cguagauacc     1320

gucucugucg gcaacacacu guacugcgua aacaagcaag aaggaaaauc ccucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucguuu uccccucaga ugaauuugac     1440

gccucgauau cacaagucaa cgaaaagaua aaucaguccc ucgccuucau ccgaaaaucc     1500

gacgaacucc uccacaacgu uaacgcagga aaguccacca caaacaucau gauaacuaca     1560

aucauaauag ucauuaucgu cauacuccuc ucccuaaucg ccguaggccu gcuacucuac     1620

ugcaaagccc gcucaacccc cgucacucuc ucaaaagacc aacucuccgg caucaauaac     1680

aucgccuucu caaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  4813
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4813
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4814
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4814
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc gguccacccc ggugacccug agcaaggacc agcucuccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4815
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4815
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4816
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4816
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcucuacacc ggugacccug agcaaggacc agcucuccgg cauaaacaau     1680

aucgcauucu caaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4817
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4817
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4818
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4818
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gauccacacc ugugacccuu agcaaggacc agcucucugg gauuaacaau     1680

aucgcuuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4819
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4819
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuc uaauacucaa agccaacgca      120

auaacaacaa uauuaacagc cguaacauuu ugcuucgcau caggucaaaa cauaacagaa      180

gaguucuacc aauccacaug cucagcagua ucaaaaggau auuuaagugc ucuaagaaca      240

ggaugguaca cauccguaau aacaaucgaa cuaucaaaca uaaaagaaaa uaaauguaau      300

ggaacagacg ccaaaguaaa auuaaucaaa caagaacuag acaaauacaa aaacgcaguu      360

acugaauuac aauuauuaau gcaaucaaca ccggccacag gaucuggauc agcaauaugc      420

ucaggaguag cagucugcaa aguauuacac cuagaagggg aaguuaauaa aaucaaauca      480

gcauuacuau ccaccaacaa agcgguaguu ucacucucca acggcguauc ugucuuaaca      540

uucaaaguau uagaccuaaa aaacuacauu gacaaacaac uacuaccaau ccuaaacaaa      600

caaucauguu ccauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuauuagaaa uaacaagaga auuuuccguc aaugcaggag uuacuacccc ugucuccacc      720

uauaugcuaa ccaauuccga acucuuauca uuaauaaacg acaugccuau cacaaaugac      780

caaaaaaaau uaaugagcaa caacguacaa auaguacgac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu ccuagcauac guuguacaac uaccacuaua cggagucaua      900

gauaccccau gcuggaaacu ccauacaagc ccacuaugca cuacaaacac aaaagaaggc      960

ucuaauauau gucuaacaag aacagaccga ggaugguacu gcgauaaugc cggcucaguc     1020

ucauucuuuc cgcaagccga aacuuguaaa guacaaagua acagaguauu uugugacacc     1080

augaacucaa gaacccuccc aagcgaaguc aaucuaugca acguugauau auucaauccc     1140

aaauacgacu gcaaaaucau gaccucaaaa acagacguca gcucauccgu uauaacauca     1200

cuaggagcca ucguaucuug cuauggaaaa acaaaaugca cagcaagcaa uaaaaacaga     1260

ggcauaauaa aaacauucuc aaauggaugc gacuacguau caaacaaagg agucgacaca     1320

guuuccguag gaaacacuuu auacugcgua aacaaacaag aaggaaaauc auuauacguc     1380

aaaggugaac caauaauaaa cuucuacgau ccacuuguau ucccaucaga cgaauuugac     1440

gcaucaauuu cacaaguaaa cgaaaaaaua aaccaaucac ucgcauucau aagaaaauca     1500

gaugaacuac uacauaacgu aaacgcagga aaauccacaa caaacaucau gauaacaacc     1560

aucauaaucg uaauaaucgu aauacuauua ucccuaauug caguaggauu acucuuauau     1620

ugcaaagcaa gaucaacacc aguaacccuc aguaaagacc aacuauccgg aauaaauaac     1680

aucgcauucu caaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4820
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4820
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacugc ucauccucaa agccaacgcc      120

aucaccacca uucuuaccgc cgucacauuc ugcuucgccu caggccaaaa caucaccgaa      180

gaauuuuacc aauccacuug uucagccguc ucaaaaggau accuaucagc ccuccguacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaggucaa acugauaaaa caagaacuug auaaauacaa aaacgccguc      360

acugaacucc aacuccucau gcaauccacu cccgcuacug gcucuggcuc cgccaucugc      420

ucuggcgucg ccgucuguaa aguacuccac cucgaagggg aagucaacaa aaucaaauca      480

gcccuccuua gcaccaacaa ggccgucguc ucccucucaa acggagucag cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaaacaac uccugcccau ccuaaauaaa      600

caauccugcu cuaucuccaa uaucgaaacc guuauagagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgcaggcg ucaccacccc ugugucaacc      720

uacaugcuca ccaacagcga acuacucuca cucaucaaug acaugcccau caccaacgac      780

caaaagaaac ucauguccaa caacguccaa aucguacguc aacaauccua cagcaucaug      840

ugcaucauaa aagaagaagu ccucgccuac gucguccaac uuccccucua cggcgucaua      900

gacacccccu gcuggaaacu gcauaccuca ccccuaugca ccaccaacac uaaagaaggc      960

uccaacaucu gccucacccg cacggaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aacuuguaaa guccaaucca acagagucuu cugcgacacc     1080

augaacucua gaacgcugcc auccgaggua aaccuaugca acgucgacau cuucaauccc     1140

aaauacgacu gcaagaucau gaccucaaaa accgacguau ccuccucagu aaucaccagu     1200

cucggagcua ucgucuccug cuacggcaaa accaaaugca cggccucuaa caaaaaccgc     1260

ggcaucauca aaaccuucuc aaacggaugc gacuacguca gcaacaaagg cguagauacc     1320

gucucugucg gcaacacacu guacugcgua aacaagcaag aaggaaaauc ccucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucguuu uccccucaga ugaauuugac     1440

gccucgauau cacaagucaa cgaaaagaua aaucaguccc ucgccuucau ccgaaaaucc     1500

gacgaacucc uccacaacgu uaacgcagga aaguccacca caaacaucau gauaacuaca     1560

aucauaauag ucauuaucgu cauacuccuc ucccuaaucg ccguaggccu gcuacucuac     1620

ugcaaagccc gcucaacccc cgucacucuc ucaaaagacc aacucuccgg caucaauaac     1680

aucgccuucu caaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  4821
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4821
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4822
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4822
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4823
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4823
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4824
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4824
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcauucucaa     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4825
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4825
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4826
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4826
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcuuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4827
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4827
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uacucaaagc caacgcaaua acaacaauau      120

uaacagccgu aacauuuugc uucgcaucag gucaaaacau aacagaagag uucuaccaau      180

ccacaugcuc agcaguauca aaaggauauu uaagugcucu aagaacagga ugguacacau      240

ccguaauaac aaucgaacua ucaaacauaa aagaaaauaa auguaaugga acagacgcca      300

aaguaaaauu aaucaaacaa gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau      360

uauuaaugca aucaacaccg gccacaggau cuggaucagc aauaugcuca ggaguagcag      420

ucugcaaagu auuacaccua gaaggggaag uuaauaaaau caaaucagca uuacuaucca      480

ccaacaaagc gguaguuuca cucuccaacg gcguaucugu cuuaacauuc aaaguauuag      540

accuaaaaaa cuacauugac aaacaacuac uaccaauccu aaacaaacaa ucauguucca      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua uuagaaauaa      660

caagagaauu uuccgucaau gcaggaguua cuaccccugu cuccaccuau augcuaacca      720

auuccgaacu cuuaucauua auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa      780

ugagcaacaa cguacaaaua guacgacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguccu agcauacguu guacaacuac cacuauacgg agucauagau accccaugcu      900

ggaaacucca uacaagccca cuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacaagaac agaccgagga ugguacugcg auaaugccgg cucagucuca uucuuuccgc     1020

aagccgaaac uuguaaagua caaaguaaca gaguauuuug ugacaccaug aacucaagaa     1080

cccucccaag cgaagucaau cuaugcaacg uugauauauu caaucccaaa uacgacugca     1140

aaaucaugac cucaaaaaca gacgucagcu cauccguuau aacaucacua ggagccaucg     1200

uaucuugcua uggaaaaaca aaaugcacag caagcaauaa aaacagaggc auaauaaaaa     1260

cauucucaaa uggaugcgac uacguaucaa acaaaggagu cgacacaguu uccguaggaa     1320

acacuuuaua cugcguaaac aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa     1380

uaauaaacuu cuacgaucca cuuguauucc caucagacga auuugacgca ucaauuucac     1440

aaguaaacga aaaaauaaac caaucacucg cauucauaag aaaaucagau gaacuacuac     1500

auaacguaaa cgcaggaaaa uccacaacaa acaucaugau aacaaccauc auaaucguaa     1560

uaaucguaau acuauuaucc cuaauugcag uaggauuacu cuuauauugc aaagcaagau     1620

caacaccagu aacccucagu aaagaccaac uauccggaau aaauaacauc gcauucucaa     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4828
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4828
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacugcuca uccucaaagc caacgccauc accaccauuc      120

uuaccgccgu cacauucugc uucgccucag gccaaaacau caccgaagaa uuuuaccaau      180

ccacuuguuc agccgucuca aaaggauacc uaucagcccu ccguaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaacauaa aagaaaacaa augcaacggc accgacgcca      300

aggucaaacu gauaaaacaa gaacuugaua aauacaaaaa cgccgucacu gaacuccaac      360

uccucaugca auccacuccc gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg      420

ucuguaaagu acuccaccuc gaaggggaag ucaacaaaau caaaucagcc cuccuuagca      480

ccaacaaggc cgucgucucc cucucaaacg gagucagcgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aaacaacucc ugcccauccu aaauaaacaa uccugcucua      600

ucuccaauau cgaaaccguu auagaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gcaggcguca ccaccccugu gucaaccuac augcucacca      720

acagcgaacu acucucacuc aucaaugaca ugcccaucac caacgaccaa aagaaacuca      780

uguccaacaa cguccaaauc guacgucaac aauccuacag caucaugugc aucauaaaag      840

aagaaguccu cgccuacguc guccaacuuc cccucuacgg cgucauagac acccccugcu      900

ggaaacugca uaccucaccc cuaugcacca ccaacacuaa agaaggcucc aacaucugcc      960

ucacccgcac ggaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac uuguaaaguc caauccaaca gagucuucug cgacaccaug aacucuagaa     1080

cgcugccauc cgagguaaac cuaugcaacg ucgacaucuu caaucccaaa uacgacugca     1140

agaucaugac cucaaaaacc gacguauccu ccucaguaau caccagucuc ggagcuaucg     1200

ucuccugcua cggcaaaacc aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa     1260

ccuucucaaa cggaugcgac uacgucagca acaaaggcgu agauaccguc ucugucggca     1320

acacacugua cugcguaaac aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucguuuucc ccucagauga auuugacgcc ucgauaucac     1440

aagucaacga aaagauaaau cagucccucg ccuucauccg aaaauccgac gaacuccucc     1500

acaacguuaa cgcaggaaag uccaccacaa acaucaugau aacuacaauc auaauaguca     1560

uuaucgucau acuccucucc cuaaucgccg uaggccugcu acucuacugc aaagcccgcu     1620

caacccccgu cacucucuca aaagaccaac ucuccggcau caauaacauc gccuucucaa     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  4829
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4829
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4830
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4830
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

ccaccccggu gacccugagc aaggaccagc ucuccgggau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4831
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4831
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4832
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4832
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

cuacaccggu gacccugagc aaggaccagc ucuccggcau aaacaauauc gcauucucaa     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4833
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4833
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4834
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4834
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

ccacaccugu gacccuuagc aaggaccagc ucucugggau uaacaauauc gcuuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4835
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4835
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuucuaa uacucaaagc caacgcaaua acaacaauau      120

uaacagccgu aacauuuugc uucgcaucag gucaaaacau aacagaagag uucuaccaau      180

ccacaugcuc agcaguauca aaaggauauu uaagugcucu aagaacagga ugguacacau      240

ccguaauaac aaucgaacua ucaaacauaa aagaaaauaa auguaaugga acagacgcca      300

aaguaaaauu aaucaaacaa gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau      360

uauuaaugca aucaacaccg gccacaggau cuggaucagc aauaugcuca ggaguagcag      420

ucugcaaagu auuacaccua gaaggggaag uuaauaaaau caaaucagca uuacuaucca      480

ccaacaaagc gguaguuuca cucuccaacg gcguaucugu cuuaacauuc aaaguauuag      540

accuaaaaaa cuacauugac aaacaacuac uaccaauccu aaacaaacaa ucauguucca      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua uuagaaauaa      660

caagagaauu uuccgucaau gcaggaguua cuaccccugu cuccaccuau augcuaacca      720

auuccgaacu cuuaucauua auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa      780

ugagcaacaa cguacaaaua guacgacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguccu agcauacguu guacaacuac cacuauacgg agucauagau accccaugcu      900

ggaaacucca uacaagccca cuaugcacua caaacacaaa agaaggcucu aauauauguc      960

uaacaagaac agaccgagga ugguacugcg auaaugccgg cucagucuca uucuuuccgc     1020

aagccgaaac uuguaaagua caaaguaaca gaguauuuug ugacaccaug aacucaagaa     1080

cccucccaag cgaagucaau cuaugcaacg uugauauauu caaucccaaa uacgacugca     1140

aaaucaugac cucaaaaaca gacgucagcu cauccguuau aacaucacua ggagccaucg     1200

uaucuugcua uggaaaaaca aaaugcacag caagcaauaa aaacagaggc auaauaaaaa     1260

cauucucaaa uggaugcgac uacguaucaa acaaaggagu cgacacaguu uccguaggaa     1320

acacuuuaua cugcguaaac aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa     1380

uaauaaacuu cuacgaucca cuuguauucc caucagacga auuugacgca ucaauuucac     1440

aaguaaacga aaaaauaaac caaucacucg cauucauaag aaaaucagau gaacuacuac     1500

auaacguaaa cgcaggaaaa uccacaacaa acaucaugau aacaaccauc auaaucguaa     1560

uaaucguaau acuauuaucc cuaauugcag uaggauuacu cuuauauugc aaagcaagau     1620

caacaccagu aacccucagu aaagaccaac uauccggaau aaauaacauc gcauucucaa     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4836
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4836
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacugcuca uccucaaagc caacgccauc accaccauuc      120

uuaccgccgu cacauucugc uucgccucag gccaaaacau caccgaagaa uuuuaccaau      180

ccacuuguuc agccgucuca aaaggauacc uaucagcccu ccguaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaacauaa aagaaaacaa augcaacggc accgacgcca      300

aggucaaacu gauaaaacaa gaacuugaua aauacaaaaa cgccgucacu gaacuccaac      360

uccucaugca auccacuccc gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg      420

ucuguaaagu acuccaccuc gaaggggaag ucaacaaaau caaaucagcc cuccuuagca      480

ccaacaaggc cgucgucucc cucucaaacg gagucagcgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aaacaacucc ugcccauccu aaauaaacaa uccugcucua      600

ucuccaauau cgaaaccguu auagaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gcaggcguca ccaccccugu gucaaccuac augcucacca      720

acagcgaacu acucucacuc aucaaugaca ugcccaucac caacgaccaa aagaaacuca      780

uguccaacaa cguccaaauc guacgucaac aauccuacag caucaugugc aucauaaaag      840

aagaaguccu cgccuacguc guccaacuuc cccucuacgg cgucauagac acccccugcu      900

ggaaacugca uaccucaccc cuaugcacca ccaacacuaa agaaggcucc aacaucugcc      960

ucacccgcac ggaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac uuguaaaguc caauccaaca gagucuucug cgacaccaug aacucuagaa     1080

cgcugccauc cgagguaaac cuaugcaacg ucgacaucuu caaucccaaa uacgacugca     1140

agaucaugac cucaaaaacc gacguauccu ccucaguaau caccagucuc ggagcuaucg     1200

ucuccugcua cggcaaaacc aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa     1260

ccuucucaaa cggaugcgac uacgucagca acaaaggcgu agauaccguc ucugucggca     1320

acacacugua cugcguaaac aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucguuuucc ccucagauga auuugacgcc ucgauaucac     1440

aagucaacga aaagauaaau cagucccucg ccuucauccg aaaauccgac gaacuccucc     1500

acaacguuaa cgcaggaaag uccaccacaa acaucaugau aacuacaauc auaauaguca     1560

uuaucgucau acuccucucc cuaaucgccg uaggccugcu acucuacugc aaagcccgcu     1620

caacccccgu cacucucuca aaagaccaac ucuccggcau caauaacauc gccuucucaa     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  4837
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4837
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4838
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4838
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4839
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4839
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4840
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4840
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcauucuc aaacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4841
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4841
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4842
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4842
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcuuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4843
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4843
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauacucaaa gccaacgcaa uaacaacaau auuaacagcc      120

guaacauuuu gcuucgcauc aggucaaaac auaacagaag aguucuacca auccacaugc      180

ucagcaguau caaaaggaua uuuaagugcu cuaagaacag gaugguacac auccguaaua      240

acaaucgaac uaucaaacau aaaagaaaau aaauguaaug gaacagacgc caaaguaaaa      300

uuaaucaaac aagaacuaga caaauacaaa aacgcaguua cugaauuaca auuauuaaug      360

caaucaacac cggccacagg aucuggauca gcaauaugcu caggaguagc agucugcaaa      420

guauuacacc uagaagggga aguuaauaaa aucaaaucag cauuacuauc caccaacaaa      480

gcgguaguuu cacucuccaa cggcguaucu gucuuaacau ucaaaguauu agaccuaaaa      540

aacuacauug acaaacaacu acuaccaauc cuaaacaaac aaucauguuc cauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uauuagaaau aacaagagaa      660

uuuuccguca augcaggagu uacuaccccu gucuccaccu auaugcuaac caauuccgaa      720

cucuuaucau uaauaaacga caugccuauc acaaaugacc aaaaaaaauu aaugagcaac      780

aacguacaaa uaguacgaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguc      840

cuagcauacg uuguacaacu accacuauac ggagucauag auaccccaug cuggaaacuc      900

cauacaagcc cacuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacaaga      960

acagaccgag gaugguacug cgauaaugcc ggcucagucu cauucuuucc gcaagccgaa     1020

acuuguaaag uacaaaguaa cagaguauuu ugugacacca ugaacucaag aacccuccca     1080

agcgaaguca aucuaugcaa cguugauaua uucaauccca aauacgacug caaaaucaug     1140

accucaaaaa cagacgucag cucauccguu auaacaucac uaggagccau cguaucuugc     1200

uauggaaaaa caaaaugcac agcaagcaau aaaaacagag gcauaauaaa aacauucuca     1260

aauggaugcg acuacguauc aaacaaagga gucgacacag uuuccguagg aaacacuuua     1320

uacugcguaa acaaacaaga aggaaaauca uuauacguca aaggugaacc aauaauaaac     1380

uucuacgauc cacuuguauu cccaucagac gaauuugacg caucaauuuc acaaguaaac     1440

gaaaaaauaa accaaucacu cgcauucaua agaaaaucag augaacuacu acauaacgua     1500

aacgcaggaa aauccacaac aaacaucaug auaacaacca ucauaaucgu aauaaucgua     1560

auacuauuau cccuaauugc aguaggauua cucuuauauu gcaaagcaag aucaacacca     1620

guaacccuca guaaagacca acuauccgga auaaauaaca ucgcauucuc aaacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4844
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4844
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacugcu cauccucaaa gccaacgcca ucaccaccau ucuuaccgcc      120

gucacauucu gcuucgccuc aggccaaaac aucaccgaag aauuuuacca auccacuugu      180

ucagccgucu caaaaggaua ccuaucagcc cuccguaccg gcugguacac cucggucaua      240

acaauagaac ucuccaacau aaaagaaaac aaaugcaacg gcaccgacgc caaggucaaa      300

cugauaaaac aagaacuuga uaaauacaaa aacgccguca cugaacucca acuccucaug      360

caauccacuc ccgcuacugg cucuggcucc gccaucugcu cuggcgucgc cgucuguaaa      420

guacuccacc ucgaagggga agucaacaaa aucaaaucag cccuccuuag caccaacaag      480

gccgucgucu cccucucaaa cggagucagc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaaacaacu ccugcccauc cuaaauaaac aauccugcuc uaucuccaau      600

aucgaaaccg uuauagaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgcaggcgu caccaccccu gugucaaccu acaugcucac caacagcgaa      720

cuacucucac ucaucaauga caugcccauc accaacgacc aaaagaaacu cauguccaac      780

aacguccaaa ucguacguca acaauccuac agcaucaugu gcaucauaaa agaagaaguc      840

cucgccuacg ucguccaacu uccccucuac ggcgucauag acacccccug cuggaaacug      900

cauaccucac cccuaugcac caccaacacu aaagaaggcu ccaacaucug ccucacccgc      960

acggaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

acuuguaaag uccaauccaa cagagucuuc ugcgacacca ugaacucuag aacgcugcca     1080

uccgagguaa accuaugcaa cgucgacauc uucaauccca aauacgacug caagaucaug     1140

accucaaaaa ccgacguauc cuccucagua aucaccaguc ucggagcuau cgucuccugc     1200

uacggcaaaa ccaaaugcac ggccucuaac aaaaaccgcg gcaucaucaa aaccuucuca     1260

aacggaugcg acuacgucag caacaaaggc guagauaccg ucucugucgg caacacacug     1320

uacugcguaa acaagcaaga aggaaaaucc cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucguuuu ccccucagau gaauuugacg ccucgauauc acaagucaac     1440

gaaaagauaa aucagucccu cgccuucauc cgaaaauccg acgaacuccu ccacaacguu     1500

aacgcaggaa aguccaccac aaacaucaug auaacuacaa ucauaauagu cauuaucguc     1560

auacuccucu cccuaaucgc cguaggccug cuacucuacu gcaaagcccg cucaaccccc     1620

gucacucucu caaaagacca acucuccggc aucaauaaca ucgccuucuc aaacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  4845
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4845
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4846
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4846
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg guccaccccg     1620

gugacccuga gcaaggacca gcucuccggg aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4847
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4847
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4848
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4848
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cucuacaccg     1620

gugacccuga gcaaggacca gcucuccggc auaaacaaua ucgcauucuc aaacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4849
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4849
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4850
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4850
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag auccacaccu     1620

gugacccuua gcaaggacca gcucucuggg auuaacaaua ucgcuuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4851
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4851
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuucu aauacucaaa gccaacgcaa uaacaacaau auuaacagcc      120

guaacauuuu gcuucgcauc aggucaaaac auaacagaag aguucuacca auccacaugc      180

ucagcaguau caaaaggaua uuuaagugcu cuaagaacag gaugguacac auccguaaua      240

acaaucgaac uaucaaacau aaaagaaaau aaauguaaug gaacagacgc caaaguaaaa      300

uuaaucaaac aagaacuaga caaauacaaa aacgcaguua cugaauuaca auuauuaaug      360

caaucaacac cggccacagg aucuggauca gcaauaugcu caggaguagc agucugcaaa      420

guauuacacc uagaagggga aguuaauaaa aucaaaucag cauuacuauc caccaacaaa      480

gcgguaguuu cacucuccaa cggcguaucu gucuuaacau ucaaaguauu agaccuaaaa      540

aacuacauug acaaacaacu acuaccaauc cuaaacaaac aaucauguuc cauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uauuagaaau aacaagagaa      660

uuuuccguca augcaggagu uacuaccccu gucuccaccu auaugcuaac caauuccgaa      720

cucuuaucau uaauaaacga caugccuauc acaaaugacc aaaaaaaauu aaugagcaac      780

aacguacaaa uaguacgaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguc      840

cuagcauacg uuguacaacu accacuauac ggagucauag auaccccaug cuggaaacuc      900

cauacaagcc cacuaugcac uacaaacaca aaagaaggcu cuaauauaug ucuaacaaga      960

acagaccgag gaugguacug cgauaaugcc ggcucagucu cauucuuucc gcaagccgaa     1020

acuuguaaag uacaaaguaa cagaguauuu ugugacacca ugaacucaag aacccuccca     1080

agcgaaguca aucuaugcaa cguugauaua uucaauccca aauacgacug caaaaucaug     1140

accucaaaaa cagacgucag cucauccguu auaacaucac uaggagccau cguaucuugc     1200

uauggaaaaa caaaaugcac agcaagcaau aaaaacagag gcauaauaaa aacauucuca     1260

aauggaugcg acuacguauc aaacaaagga gucgacacag uuuccguagg aaacacuuua     1320

uacugcguaa acaaacaaga aggaaaauca uuauacguca aaggugaacc aauaauaaac     1380

uucuacgauc cacuuguauu cccaucagac gaauuugacg caucaauuuc acaaguaaac     1440

gaaaaaauaa accaaucacu cgcauucaua agaaaaucag augaacuacu acauaacgua     1500

aacgcaggaa aauccacaac aaacaucaug auaacaacca ucauaaucgu aauaaucgua     1560

auacuauuau cccuaauugc aguaggauua cucuuauauu gcaaagcaag aucaacacca     1620

guaacccuca guaaagacca acuauccgga auaaauaaca ucgcauucuc aaacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4852
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4852
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacugcu cauccucaaa gccaacgcca ucaccaccau ucuuaccgcc      120

gucacauucu gcuucgccuc aggccaaaac aucaccgaag aauuuuacca auccacuugu      180

ucagccgucu caaaaggaua ccuaucagcc cuccguaccg gcugguacac cucggucaua      240

acaauagaac ucuccaacau aaaagaaaac aaaugcaacg gcaccgacgc caaggucaaa      300

cugauaaaac aagaacuuga uaaauacaaa aacgccguca cugaacucca acuccucaug      360

caauccacuc ccgcuacugg cucuggcucc gccaucugcu cuggcgucgc cgucuguaaa      420

guacuccacc ucgaagggga agucaacaaa aucaaaucag cccuccuuag caccaacaag      480

gccgucgucu cccucucaaa cggagucagc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaaacaacu ccugcccauc cuaaauaaac aauccugcuc uaucuccaau      600

aucgaaaccg uuauagaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgcaggcgu caccaccccu gugucaaccu acaugcucac caacagcgaa      720

cuacucucac ucaucaauga caugcccauc accaacgacc aaaagaaacu cauguccaac      780

aacguccaaa ucguacguca acaauccuac agcaucaugu gcaucauaaa agaagaaguc      840

cucgccuacg ucguccaacu uccccucuac ggcgucauag acacccccug cuggaaacug      900

cauaccucac cccuaugcac caccaacacu aaagaaggcu ccaacaucug ccucacccgc      960

acggaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

acuuguaaag uccaauccaa cagagucuuc ugcgacacca ugaacucuag aacgcugcca     1080

uccgagguaa accuaugcaa cgucgacauc uucaauccca aauacgacug caagaucaug     1140

accucaaaaa ccgacguauc cuccucagua aucaccaguc ucggagcuau cgucuccugc     1200

uacggcaaaa ccaaaugcac ggccucuaac aaaaaccgcg gcaucaucaa aaccuucuca     1260

aacggaugcg acuacgucag caacaaaggc guagauaccg ucucugucgg caacacacug     1320

uacugcguaa acaagcaaga aggaaaaucc cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucguuuu ccccucagau gaauuugacg ccucgauauc acaagucaac     1440

gaaaagauaa aucagucccu cgccuucauc cgaaaauccg acgaacuccu ccacaacguu     1500

aacgcaggaa aguccaccac aaacaucaug auaacuacaa ucauaauagu cauuaucguc     1560

auacuccucu cccuaaucgc cguaggccug cuacucuacu gcaaagcccg cucaaccccc     1620

gucacucucu caaaagacca acucuccggc aucaauaaca ucgccuucuc aaacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  4853
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4853
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4854
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4854
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4855
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4855
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4856
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4856
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cauucucaaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4857
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4857
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4858
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4858
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cuuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4859
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4859
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau acucaaagcc      120

aacgcaauaa caacaauauu aacagccgua acauuuugcu ucgcaucagg ucaaaacaua      180

acagaagagu ucuaccaauc cacaugcuca gcaguaucaa aaggauauuu aagugcucua      240

agaacaggau gguacacauc cguaauaaca aucgaacuau caaacauaaa agaaaauaaa      300

uguaauggaa cagacgccaa aguaaaauua aucaaacaag aacuagacaa auacaaaaac      360

gcaguuacug aauuacaauu auuaaugcaa ucaacaccgg ccacaggauc uggaucagca      420

auaugcucag gaguagcagu cugcaaagua uuacaccuag aaggggaagu uaauaaaauc      480

aaaucagcau uacuauccac caacaaagcg guaguuucac ucuccaacgg cguaucuguc      540

uuaacauuca aaguauuaga ccuaaaaaac uacauugaca aacaacuacu accaauccua      600

aacaaacaau cauguuccau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuau uagaaauaac aagagaauuu uccgucaaug caggaguuac uaccccuguc      720

uccaccuaua ugcuaaccaa uuccgaacuc uuaucauuaa uaaacgacau gccuaucaca      780

aaugaccaaa aaaaauuaau gagcaacaac guacaaauag uacgacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguccua gcauacguug uacaacuacc acuauacgga      900

gucauagaua ccccaugcug gaaacuccau acaagcccac uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacaagaaca gaccgaggau gguacugcga uaaugccggc     1020

ucagucucau ucuuuccgca agccgaaacu uguaaaguac aaaguaacag aguauuuugu     1080

gacaccauga acucaagaac ccucccaagc gaagucaauc uaugcaacgu ugauauauuc     1140

aaucccaaau acgacugcaa aaucaugacc ucaaaaacag acgucagcuc auccguuaua     1200

acaucacuag gagccaucgu aucuugcuau ggaaaaacaa aaugcacagc aagcaauaaa     1260

aacagaggca uaauaaaaac auucucaaau ggaugcgacu acguaucaaa caaaggaguc     1320

gacacaguuu ccguaggaaa cacuuuauac ugcguaaaca aacaagaagg aaaaucauua     1380

uacgucaaag gugaaccaau aauaaacuuc uacgauccac uuguauuccc aucagacgaa     1440

uuugacgcau caauuucaca aguaaacgaa aaaauaaacc aaucacucgc auucauaaga     1500

aaaucagaug aacuacuaca uaacguaaac gcaggaaaau ccacaacaaa caucaugaua     1560

acaaccauca uaaucguaau aaucguaaua cuauuauccc uaauugcagu aggauuacuc     1620

uuauauugca aagcaagauc aacaccagua acccucagua aagaccaacu auccggaaua     1680

aauaacaucg cauucucaaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4860
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4860
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacugcucau ccucaaagcc      120

aacgccauca ccaccauucu uaccgccguc acauucugcu ucgccucagg ccaaaacauc      180

accgaagaau uuuaccaauc cacuuguuca gccgucucaa aaggauaccu aucagcccuc      240

cguaccggcu gguacaccuc ggucauaaca auagaacucu ccaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa ggucaaacug auaaaacaag aacuugauaa auacaaaaac      360

gccgucacug aacuccaacu ccucaugcaa uccacucccg cuacuggcuc uggcuccgcc      420

aucugcucug gcgucgccgu cuguaaagua cuccaccucg aaggggaagu caacaaaauc      480

aaaucagccc uccuuagcac caacaaggcc gucgucuccc ucucaaacgg agucagcguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca aacaacuccu gcccauccua      600

aauaaacaau ccugcucuau cuccaauauc gaaaccguua uagaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg caggcgucac caccccugug      720

ucaaccuaca ugcucaccaa cagcgaacua cucucacuca ucaaugacau gcccaucacc      780

aacgaccaaa agaaacucau guccaacaac guccaaaucg uacgucaaca auccuacagc      840

aucaugugca ucauaaaaga agaaguccuc gccuacgucg uccaacuucc ccucuacggc      900

gucauagaca cccccugcug gaaacugcau accucacccc uaugcaccac caacacuaaa      960

gaaggcucca acaucugccu cacccgcacg gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacu uguaaagucc aauccaacag agucuucugc     1080

gacaccauga acucuagaac gcugccaucc gagguaaacc uaugcaacgu cgacaucuuc     1140

aaucccaaau acgacugcaa gaucaugacc ucaaaaaccg acguauccuc cucaguaauc     1200

accagucucg gagcuaucgu cuccugcuac ggcaaaacca aaugcacggc cucuaacaaa     1260

aaccgcggca ucaucaaaac cuucucaaac ggaugcgacu acgucagcaa caaaggcgua     1320

gauaccgucu cugucggcaa cacacuguac ugcguaaaca agcaagaagg aaaaucccuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucguuuuccc cucagaugaa     1440

uuugacgccu cgauaucaca agucaacgaa aagauaaauc agucccucgc cuucauccga     1500

aaauccgacg aacuccucca caacguuaac gcaggaaagu ccaccacaaa caucaugaua     1560

acuacaauca uaauagucau uaucgucaua cuccucuccc uaaucgccgu aggccugcua     1620

cucuacugca aagcccgcuc aacccccguc acucucucaa aagaccaacu cuccggcauc     1680

aauaacaucg ccuucucaaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  4861
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4861
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4862
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4862
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccgguc caccccggug acccugagca aggaccagcu cuccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4863
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4863
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4864
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4864
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcuc uacaccggug acccugagca aggaccagcu cuccggcaua     1680

aacaauaucg cauucucaaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4865
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4865
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4866
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4866
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagauc cacaccugug acccuuagca aggaccagcu cucugggauu     1680

aacaauaucg cuuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4867
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4867
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuucuaau acucaaagcc      120

aacgcaauaa caacaauauu aacagccgua acauuuugcu ucgcaucagg ucaaaacaua      180

acagaagagu ucuaccaauc cacaugcuca gcaguaucaa aaggauauuu aagugcucua      240

agaacaggau gguacacauc cguaauaaca aucgaacuau caaacauaaa agaaaauaaa      300

uguaauggaa cagacgccaa aguaaaauua aucaaacaag aacuagacaa auacaaaaac      360

gcaguuacug aauuacaauu auuaaugcaa ucaacaccgg ccacaggauc uggaucagca      420

auaugcucag gaguagcagu cugcaaagua uuacaccuag aaggggaagu uaauaaaauc      480

aaaucagcau uacuauccac caacaaagcg guaguuucac ucuccaacgg cguaucuguc      540

uuaacauuca aaguauuaga ccuaaaaaac uacauugaca aacaacuacu accaauccua      600

aacaaacaau cauguuccau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuau uagaaauaac aagagaauuu uccgucaaug caggaguuac uaccccuguc      720

uccaccuaua ugcuaaccaa uuccgaacuc uuaucauuaa uaaacgacau gccuaucaca      780

aaugaccaaa aaaaauuaau gagcaacaac guacaaauag uacgacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguccua gcauacguug uacaacuacc acuauacgga      900

gucauagaua ccccaugcug gaaacuccau acaagcccac uaugcacuac aaacacaaaa      960

gaaggcucua auauaugucu aacaagaaca gaccgaggau gguacugcga uaaugccggc     1020

ucagucucau ucuuuccgca agccgaaacu uguaaaguac aaaguaacag aguauuuugu     1080

gacaccauga acucaagaac ccucccaagc gaagucaauc uaugcaacgu ugauauauuc     1140

aaucccaaau acgacugcaa aaucaugacc ucaaaaacag acgucagcuc auccguuaua     1200

acaucacuag gagccaucgu aucuugcuau ggaaaaacaa aaugcacagc aagcaauaaa     1260

aacagaggca uaauaaaaac auucucaaau ggaugcgacu acguaucaaa caaaggaguc     1320

gacacaguuu ccguaggaaa cacuuuauac ugcguaaaca aacaagaagg aaaaucauua     1380

uacgucaaag gugaaccaau aauaaacuuc uacgauccac uuguauuccc aucagacgaa     1440

uuugacgcau caauuucaca aguaaacgaa aaaauaaacc aaucacucgc auucauaaga     1500

aaaucagaug aacuacuaca uaacguaaac gcaggaaaau ccacaacaaa caucaugaua     1560

acaaccauca uaaucguaau aaucguaaua cuauuauccc uaauugcagu aggauuacuc     1620

uuauauugca aagcaagauc aacaccagua acccucagua aagaccaacu auccggaaua     1680

aauaacaucg cauucucaaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4868
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4868
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacugcucau ccucaaagcc      120

aacgccauca ccaccauucu uaccgccguc acauucugcu ucgccucagg ccaaaacauc      180

accgaagaau uuuaccaauc cacuuguuca gccgucucaa aaggauaccu aucagcccuc      240

cguaccggcu gguacaccuc ggucauaaca auagaacucu ccaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa ggucaaacug auaaaacaag aacuugauaa auacaaaaac      360

gccgucacug aacuccaacu ccucaugcaa uccacucccg cuacuggcuc uggcuccgcc      420

aucugcucug gcgucgccgu cuguaaagua cuccaccucg aaggggaagu caacaaaauc      480

aaaucagccc uccuuagcac caacaaggcc gucgucuccc ucucaaacgg agucagcguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca aacaacuccu gcccauccua      600

aauaaacaau ccugcucuau cuccaauauc gaaaccguua uagaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg caggcgucac caccccugug      720

ucaaccuaca ugcucaccaa cagcgaacua cucucacuca ucaaugacau gcccaucacc      780

aacgaccaaa agaaacucau guccaacaac guccaaaucg uacgucaaca auccuacagc      840

aucaugugca ucauaaaaga agaaguccuc gccuacgucg uccaacuucc ccucuacggc      900

gucauagaca cccccugcug gaaacugcau accucacccc uaugcaccac caacacuaaa      960

gaaggcucca acaucugccu cacccgcacg gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacu uguaaagucc aauccaacag agucuucugc     1080

gacaccauga acucuagaac gcugccaucc gagguaaacc uaugcaacgu cgacaucuuc     1140

aaucccaaau acgacugcaa gaucaugacc ucaaaaaccg acguauccuc cucaguaauc     1200

accagucucg gagcuaucgu cuccugcuac ggcaaaacca aaugcacggc cucuaacaaa     1260

aaccgcggca ucaucaaaac cuucucaaac ggaugcgacu acgucagcaa caaaggcgua     1320

gauaccgucu cugucggcaa cacacuguac ugcguaaaca agcaagaagg aaaaucccuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucguuuuccc cucagaugaa     1440

uuugacgccu cgauaucaca agucaacgaa aagauaaauc agucccucgc cuucauccga     1500

aaauccgacg aacuccucca caacguuaac gcaggaaagu ccaccacaaa caucaugaua     1560

acuacaauca uaauagucau uaucgucaua cuccucuccc uaaucgccgu aggccugcua     1620

cucuacugca aagcccgcuc aacccccguc acucucucaa aagaccaacu cuccggcauc     1680

aauaacaucg ccuucucaaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  4869
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4869
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4870
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4870
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc     1680

cugagcaagg accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4871
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4871
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4872
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4872
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcucuac accggugacc     1680

cugagcaagg accagcucuc cggcauaaac aauaucgcau ucucaaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4873
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4873
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4874
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4874
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagauccac accugugacc     1680

cuuagcaagg accagcucuc ugggauuaac aauaucgcuu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4875
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4875
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uucuaauacu caaagccaac gcaauaacaa caauauuaac agccguaaca      180

uuuugcuucg caucagguca aaacauaaca gaagaguucu accaauccac augcucagca      240

guaucaaaag gauauuuaag ugcucuaaga acaggauggu acacauccgu aauaacaauc      300

gaacuaucaa acauaaaaga aaauaaaugu aauggaacag acgccaaagu aaaauuaauc      360

aaacaagaac uagacaaaua caaaaacgca guuacugaau uacaauuauu aaugcaauca      420

acaccggcca caggaucugg aucagcaaua ugcucaggag uagcagucug caaaguauua      480

caccuagaag gggaaguuaa uaaaaucaaa ucagcauuac uauccaccaa caaagcggua      540

guuucacucu ccaacggcgu aucugucuua acauucaaag uauuagaccu aaaaaacuac      600

auugacaaac aacuacuacc aauccuaaac aaacaaucau guuccauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuauuag aaauaacaag agaauuuucc      720

gucaaugcag gaguuacuac cccugucucc accuauaugc uaaccaauuc cgaacucuua      780

ucauuaauaa acgacaugcc uaucacaaau gaccaaaaaa aauuaaugag caacaacgua      840

caaauaguac gacaacaauc auacucaauc augugcauaa uaaaagaaga aguccuagca      900

uacguuguac aacuaccacu auacggaguc auagauaccc caugcuggaa acuccauaca      960

agcccacuau gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac aagaacagac     1020

cgaggauggu acugcgauaa ugccggcuca gucucauucu uuccgcaagc cgaaacuugu     1080

aaaguacaaa guaacagagu auuuugugac accaugaacu caagaacccu cccaagcgaa     1140

gucaaucuau gcaacguuga uauauucaau cccaaauacg acugcaaaau caugaccuca     1200

aaaacagacg ucagcucauc cguuauaaca ucacuaggag ccaucguauc uugcuaugga     1260

aaaacaaaau gcacagcaag caauaaaaac agaggcauaa uaaaaacauu cucaaaugga     1320

ugcgacuacg uaucaaacaa aggagucgac acaguuuccg uaggaaacac uuuauacugc     1380

guaaacaaac aagaaggaaa aucauuauac gucaaaggug aaccaauaau aaacuucuac     1440

gauccacuug uauucccauc agacgaauuu gacgcaucaa uuucacaagu aaacgaaaaa     1500

auaaaccaau cacucgcauu cauaagaaaa ucagaugaac uacuacauaa cguaaacgca     1560

ggaaaaucca caacaaacau caugauaaca accaucauaa ucguaauaau cguaauacua     1620

uuaucccuaa uugcaguagg auuacucuua uauugcaaag caagaucaac accaguaacc     1680

cucaguaaag accaacuauc cggaauaaau aacaucgcau ucucaaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4876
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4876
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac ugcucauccu caaagccaac gccaucacca ccauucuuac cgccgucaca      180

uucugcuucg ccucaggcca aaacaucacc gaagaauuuu accaauccac uuguucagcc      240

gucucaaaag gauaccuauc agcccuccgu accggcuggu acaccucggu cauaacaaua      300

gaacucucca acauaaaaga aaacaaaugc aacggcaccg acgccaaggu caaacugaua      360

aaacaagaac uugauaaaua caaaaacgcc gucacugaac uccaacuccu caugcaaucc      420

acucccgcua cuggcucugg cuccgccauc ugcucuggcg ucgccgucug uaaaguacuc      480

caccucgaag gggaagucaa caaaaucaaa ucagcccucc uuagcaccaa caaggccguc      540

gucucccucu caaacggagu cagcguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaaac aacuccugcc cauccuaaau aaacaauccu gcucuaucuc caauaucgaa      660

accguuauag aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgcag gcgucaccac cccuguguca accuacaugc ucaccaacag cgaacuacuc      780

ucacucauca augacaugcc caucaccaac gaccaaaaga aacucauguc caacaacguc      840

caaaucguac gucaacaauc cuacagcauc augugcauca uaaaagaaga aguccucgcc      900

uacgucgucc aacuuccccu cuacggcguc auagacaccc ccugcuggaa acugcauacc      960

ucaccccuau gcaccaccaa cacuaaagaa ggcuccaaca ucugccucac ccgcacggac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaacuugu     1080

aaaguccaau ccaacagagu cuucugcgac accaugaacu cuagaacgcu gccauccgag     1140

guaaaccuau gcaacgucga caucuucaau cccaaauacg acugcaagau caugaccuca     1200

aaaaccgacg uauccuccuc aguaaucacc agucucggag cuaucgucuc cugcuacggc     1260

aaaaccaaau gcacggccuc uaacaaaaac cgcggcauca ucaaaaccuu cucaaacgga     1320

ugcgacuacg ucagcaacaa aggcguagau accgucucug ucggcaacac acuguacugc     1380

guaaacaagc aagaaggaaa aucccucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg uuuuccccuc agaugaauuu gacgccucga uaucacaagu caacgaaaag     1500

auaaaucagu cccucgccuu cauccgaaaa uccgacgaac uccuccacaa cguuaacgca     1560

ggaaagucca ccacaaacau caugauaacu acaaucauaa uagucauuau cgucauacuc     1620

cucucccuaa ucgccguagg ccugcuacuc uacugcaaag cccgcucaac ccccgucacu     1680

cucucaaaag accaacucuc cggcaucaau aacaucgccu ucucaaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4877
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4877
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4878
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4878
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4879
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4879
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4880
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4880
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcauucuc aaacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4881
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4881
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4882
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4882
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcuuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4883
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4883
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauacucaaa      120

gccaacgcaa uaacaacaau auuaacagcc guaacauuuu gcuucgcauc aggucaaaac      180

auaacagaag aguucuacca auccacaugc ucagcaguau caaaaggaua uuuaagugcu      240

cuaagaacag gaugguacac auccguaaua acaaucgaac uaucaaacau aaaagaaaau      300

aaauguaaug gaacagacgc caaaguaaaa uuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguua cugaauuaca auuauuaaug caaucaacac cggccacagg aucuggauca      420

gcaauaugcu caggaguagc agucugcaaa guauuacacc uagaagggga aguuaauaaa      480

aucaaaucag cauuacuauc caccaacaaa gcgguaguuu cacucuccaa cggcguaucu      540

gucuuaacau ucaaaguauu agaccuaaaa aacuacauug acaaacaacu acuaccaauc      600

cuaaacaaac aaucauguuc cauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uauuagaaau aacaagagaa uuuuccguca augcaggagu uacuaccccu      720

gucuccaccu auaugcuaac caauuccgaa cucuuaucau uaauaaacga caugccuauc      780

acaaaugacc aaaaaaaauu aaugagcaac aacguacaaa uaguacgaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguc cuagcauacg uuguacaacu accacuauac      900

ggagucauag auaccccaug cuggaaacuc cauacaagcc cacuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacaaga acagaccgag gaugguacug cgauaaugcc     1020

ggcucagucu cauucuuucc gcaagccgaa acuuguaaag uacaaaguaa cagaguauuu     1080

ugugacacca ugaacucaag aacccuccca agcgaaguca aucuaugcaa cguugauaua     1140

uucaauccca aauacgacug caaaaucaug accucaaaaa cagacgucag cucauccguu     1200

auaacaucac uaggagccau cguaucuugc uauggaaaaa caaaaugcac agcaagcaau     1260

aaaaacagag gcauaauaaa aacauucuca aauggaugcg acuacguauc aaacaaagga     1320

gucgacacag uuuccguagg aaacacuuua uacugcguaa acaaacaaga aggaaaauca     1380

uuauacguca aaggugaacc aauaauaaac uucuacgauc cacuuguauu cccaucagac     1440

gaauuugacg caucaauuuc acaaguaaac gaaaaaauaa accaaucacu cgcauucaua     1500

agaaaaucag augaacuacu acauaacgua aacgcaggaa aauccacaac aaacaucaug     1560

auaacaacca ucauaaucgu aauaaucgua auacuauuau cccuaauugc aguaggauua     1620

cucuuauauu gcaaagcaag aucaacacca guaacccuca guaaagacca acuauccgga     1680

auaaauaaca ucgcauucuc aaacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4884
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4884
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacugcu cauccucaaa      120

gccaacgcca ucaccaccau ucuuaccgcc gucacauucu gcuucgccuc aggccaaaac      180

aucaccgaag aauuuuacca auccacuugu ucagccgucu caaaaggaua ccuaucagcc      240

cuccguaccg gcugguacac cucggucaua acaauagaac ucuccaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaggucaaa cugauaaaac aagaacuuga uaaauacaaa      360

aacgccguca cugaacucca acuccucaug caauccacuc ccgcuacugg cucuggcucc      420

gccaucugcu cuggcgucgc cgucuguaaa guacuccacc ucgaagggga agucaacaaa      480

aucaaaucag cccuccuuag caccaacaag gccgucgucu cccucucaaa cggagucagc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaaacaacu ccugcccauc      600

cuaaauaaac aauccugcuc uaucuccaau aucgaaaccg uuauagaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccaccccu      720

gugucaaccu acaugcucac caacagcgaa cuacucucac ucaucaauga caugcccauc      780

accaacgacc aaaagaaacu cauguccaac aacguccaaa ucguacguca acaauccuac      840

agcaucaugu gcaucauaaa agaagaaguc cucgccuacg ucguccaacu uccccucuac      900

ggcgucauag acacccccug cuggaaacug cauaccucac cccuaugcac caccaacacu      960

aaagaaggcu ccaacaucug ccucacccgc acggaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa acuuguaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucuag aacgcugcca uccgagguaa accuaugcaa cgucgacauc     1140

uucaauccca aauacgacug caagaucaug accucaaaaa ccgacguauc cuccucagua     1200

aucaccaguc ucggagcuau cgucuccugc uacggcaaaa ccaaaugcac ggccucuaac     1260

aaaaaccgcg gcaucaucaa aaccuucuca aacggaugcg acuacgucag caacaaaggc     1320

guagauaccg ucucugucgg caacacacug uacugcguaa acaagcaaga aggaaaaucc     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucguuuu ccccucagau     1440

gaauuugacg ccucgauauc acaagucaac gaaaagauaa aucagucccu cgccuucauc     1500

cgaaaauccg acgaacuccu ccacaacguu aacgcaggaa aguccaccac aaacaucaug     1560

auaacuacaa ucauaauagu cauuaucguc auacuccucu cccuaaucgc cguaggccug     1620

cuacucuacu gcaaagcccg cucaaccccc gucacucucu caaaagacca acucuccggc     1680

aucaauaaca ucgccuucuc aaacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  4885
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4885
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4886
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4886
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4887
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4887
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4888
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4888
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcauucuc aaacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4889
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4889
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4890
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4890
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcuuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4891
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4891
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauacucaaa      120

gccaacgcaa uaacaacaau auuaacagcc guaacauuuu gcuucgcauc aggucaaaac      180

auaacagaag aguucuacca auccacaugc ucagcaguau caaaaggaua uuuaagugcu      240

cuaagaacag gaugguacac auccguaaua acaaucgaac uaucaaacau aaaagaaaau      300

aaauguaaug gaacagacgc caaaguaaaa uuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguua cugaauuaca auuauuaaug caaucaacac cggccacagg aucuggauca      420

gcaauaugcu caggaguagc agucugcaaa guauuacacc uagaagggga aguuaauaaa      480

aucaaaucag cauuacuauc caccaacaaa gcgguaguuu cacucuccaa cggcguaucu      540

gucuuaacau ucaaaguauu agaccuaaaa aacuacauug acaaacaacu acuaccaauc      600

cuaaacaaac aaucauguuc cauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uauuagaaau aacaagagaa uuuuccguca augcaggagu uacuaccccu      720

gucuccaccu auaugcuaac caauuccgaa cucuuaucau uaauaaacga caugccuauc      780

acaaaugacc aaaaaaaauu aaugagcaac aacguacaaa uaguacgaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguc cuagcauacg uuguacaacu accacuauac      900

ggagucauag auaccccaug cuggaaacuc cauacaagcc cacuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacaaga acagaccgag gaugguacug cgauaaugcc     1020

ggcucagucu cauucuuucc gcaagccgaa acuuguaaag uacaaaguaa cagaguauuu     1080

ugugacacca ugaacucaag aacccuccca agcgaaguca aucuaugcaa cguugauaua     1140

uucaauccca aauacgacug caaaaucaug accucaaaaa cagacgucag cucauccguu     1200

auaacaucac uaggagccau cguaucuugc uauggaaaaa caaaaugcac agcaagcaau     1260

aaaaacagag gcauaauaaa aacauucuca aauggaugcg acuacguauc aaacaaagga     1320

gucgacacag uuuccguagg aaacacuuua uacugcguaa acaaacaaga aggaaaauca     1380

uuauacguca aaggugaacc aauaauaaac uucuacgauc cacuuguauu cccaucagac     1440

gaauuugacg caucaauuuc acaaguaaac gaaaaaauaa accaaucacu cgcauucaua     1500

agaaaaucag augaacuacu acauaacgua aacgcaggaa aauccacaac aaacaucaug     1560

auaacaacca ucauaaucgu aauaaucgua auacuauuau cccuaauugc aguaggauua     1620

cucuuauauu gcaaagcaag aucaacacca guaacccuca guaaagacca acuauccgga     1680

auaaauaaca ucgcauucuc aaacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4892
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4892
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacugcu cauccucaaa      120

gccaacgcca ucaccaccau ucuuaccgcc gucacauucu gcuucgccuc aggccaaaac      180

aucaccgaag aauuuuacca auccacuugu ucagccgucu caaaaggaua ccuaucagcc      240

cuccguaccg gcugguacac cucggucaua acaauagaac ucuccaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaggucaaa cugauaaaac aagaacuuga uaaauacaaa      360

aacgccguca cugaacucca acuccucaug caauccacuc ccgcuacugg cucuggcucc      420

gccaucugcu cuggcgucgc cgucuguaaa guacuccacc ucgaagggga agucaacaaa      480

aucaaaucag cccuccuuag caccaacaag gccgucgucu cccucucaaa cggagucagc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaaacaacu ccugcccauc      600

cuaaauaaac aauccugcuc uaucuccaau aucgaaaccg uuauagaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccaccccu      720

gugucaaccu acaugcucac caacagcgaa cuacucucac ucaucaauga caugcccauc      780

accaacgacc aaaagaaacu cauguccaac aacguccaaa ucguacguca acaauccuac      840

agcaucaugu gcaucauaaa agaagaaguc cucgccuacg ucguccaacu uccccucuac      900

ggcgucauag acacccccug cuggaaacug cauaccucac cccuaugcac caccaacacu      960

aaagaaggcu ccaacaucug ccucacccgc acggaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa acuuguaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucuag aacgcugcca uccgagguaa accuaugcaa cgucgacauc     1140

uucaauccca aauacgacug caagaucaug accucaaaaa ccgacguauc cuccucagua     1200

aucaccaguc ucggagcuau cgucuccugc uacggcaaaa ccaaaugcac ggccucuaac     1260

aaaaaccgcg gcaucaucaa aaccuucuca aacggaugcg acuacgucag caacaaaggc     1320

guagauaccg ucucugucgg caacacacug uacugcguaa acaagcaaga aggaaaaucc     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucguuuu ccccucagau     1440

gaauuugacg ccucgauauc acaagucaac gaaaagauaa aucagucccu cgccuucauc     1500

cgaaaauccg acgaacuccu ccacaacguu aacgcaggaa aguccaccac aaacaucaug     1560

auaacuacaa ucauaauagu cauuaucguc auacuccucu cccuaaucgc cguaggccug     1620

cuacucuacu gcaaagcccg cucaaccccc gucacucucu caaaagacca acucuccggc     1680

aucaauaaca ucgccuucuc aaacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  4893
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4893
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4894
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4894
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4895
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4895
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4896
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4896
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcauucuc aaacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4897
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4897
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4898
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4898
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcuuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4899
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4899
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauacucaaa      120

gccaacgcaa uaacaacaau auuaacagcc guaacauuuu gcuucgcauc aggucaaaac      180

auaacagaag aguucuacca auccacaugc ucagcaguau caaaaggaua uuuaagugcu      240

cuaagaacag gaugguacac auccguaaua acaaucgaac uaucaaacau aaaagaaaau      300

aaauguaaug gaacagacgc caaaguaaaa uuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguua cugaauuaca auuauuaaug caaucaacac cggccacagg aucuggauca      420

gcaauaugcu caggaguagc agucugcaaa guauuacacc uagaagggga aguuaauaaa      480

aucaaaucag cauuacuauc caccaacaaa gcgguaguuu cacucuccaa cggcguaucu      540

gucuuaacau ucaaaguauu agaccuaaaa aacuacauug acaaacaacu acuaccaauc      600

cuaaacaaac aaucauguuc cauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uauuagaaau aacaagagaa uuuuccguca augcaggagu uacuaccccu      720

gucuccaccu auaugcuaac caauuccgaa cucuuaucau uaauaaacga caugccuauc      780

acaaaugacc aaaaaaaauu aaugagcaac aacguacaaa uaguacgaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguc cuagcauacg uuguacaacu accacuauac      900

ggagucauag auaccccaug cuggaaacuc cauacaagcc cacuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacaaga acagaccgag gaugguacug cgauaaugcc     1020

ggcucagucu cauucuuucc gcaagccgaa acuuguaaag uacaaaguaa cagaguauuu     1080

ugugacacca ugaacucaag aacccuccca agcgaaguca aucuaugcaa cguugauaua     1140

uucaauccca aauacgacug caaaaucaug accucaaaaa cagacgucag cucauccguu     1200

auaacaucac uaggagccau cguaucuugc uauggaaaaa caaaaugcac agcaagcaau     1260

aaaaacagag gcauaauaaa aacauucuca aauggaugcg acuacguauc aaacaaagga     1320

gucgacacag uuuccguagg aaacacuuua uacugcguaa acaaacaaga aggaaaauca     1380

uuauacguca aaggugaacc aauaauaaac uucuacgauc cacuuguauu cccaucagac     1440

gaauuugacg caucaauuuc acaaguaaac gaaaaaauaa accaaucacu cgcauucaua     1500

agaaaaucag augaacuacu acauaacgua aacgcaggaa aauccacaac aaacaucaug     1560

auaacaacca ucauaaucgu aauaaucgua auacuauuau cccuaauugc aguaggauua     1620

cucuuauauu gcaaagcaag aucaacacca guaacccuca guaaagacca acuauccgga     1680

auaaauaaca ucgcauucuc aaacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4900
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4900
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacugcu cauccucaaa      120

gccaacgcca ucaccaccau ucuuaccgcc gucacauucu gcuucgccuc aggccaaaac      180

aucaccgaag aauuuuacca auccacuugu ucagccgucu caaaaggaua ccuaucagcc      240

cuccguaccg gcugguacac cucggucaua acaauagaac ucuccaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaggucaaa cugauaaaac aagaacuuga uaaauacaaa      360

aacgccguca cugaacucca acuccucaug caauccacuc ccgcuacugg cucuggcucc      420

gccaucugcu cuggcgucgc cgucuguaaa guacuccacc ucgaagggga agucaacaaa      480

aucaaaucag cccuccuuag caccaacaag gccgucgucu cccucucaaa cggagucagc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaaacaacu ccugcccauc      600

cuaaauaaac aauccugcuc uaucuccaau aucgaaaccg uuauagaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccaccccu      720

gugucaaccu acaugcucac caacagcgaa cuacucucac ucaucaauga caugcccauc      780

accaacgacc aaaagaaacu cauguccaac aacguccaaa ucguacguca acaauccuac      840

agcaucaugu gcaucauaaa agaagaaguc cucgccuacg ucguccaacu uccccucuac      900

ggcgucauag acacccccug cuggaaacug cauaccucac cccuaugcac caccaacacu      960

aaagaaggcu ccaacaucug ccucacccgc acggaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa acuuguaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucuag aacgcugcca uccgagguaa accuaugcaa cgucgacauc     1140

uucaauccca aauacgacug caagaucaug accucaaaaa ccgacguauc cuccucagua     1200

aucaccaguc ucggagcuau cgucuccugc uacggcaaaa ccaaaugcac ggccucuaac     1260

aaaaaccgcg gcaucaucaa aaccuucuca aacggaugcg acuacgucag caacaaaggc     1320

guagauaccg ucucugucgg caacacacug uacugcguaa acaagcaaga aggaaaaucc     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucguuuu ccccucagau     1440

gaauuugacg ccucgauauc acaagucaac gaaaagauaa aucagucccu cgccuucauc     1500

cgaaaauccg acgaacuccu ccacaacguu aacgcaggaa aguccaccac aaacaucaug     1560

auaacuacaa ucauaauagu cauuaucguc auacuccucu cccuaaucgc cguaggccug     1620

cuacucuacu gcaaagcccg cucaaccccc gucacucucu caaaagacca acucuccggc     1680

aucaauaaca ucgccuucuc aaacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  4901
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4901
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4902
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4902
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4903
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4903
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4904
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4904
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cucuacaccg gugacccuga gcaaggacca gcucuccggc     1680

auaaacaaua ucgcauucuc aaacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4905
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4905
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4906
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4906
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag auccacaccu gugacccuua gcaaggacca gcucucuggg     1680

auuaacaaua ucgcuuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4907
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4907
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuucu aauacucaaa      120

gccaacgcaa uaacaacaau auuaacagcc guaacauuuu gcuucgcauc aggucaaaac      180

auaacagaag aguucuacca auccacaugc ucagcaguau caaaaggaua uuuaagugcu      240

cuaagaacag gaugguacac auccguaaua acaaucgaac uaucaaacau aaaagaaaau      300

aaauguaaug gaacagacgc caaaguaaaa uuaaucaaac aagaacuaga caaauacaaa      360

aacgcaguua cugaauuaca auuauuaaug caaucaacac cggccacagg aucuggauca      420

gcaauaugcu caggaguagc agucugcaaa guauuacacc uagaagggga aguuaauaaa      480

aucaaaucag cauuacuauc caccaacaaa gcgguaguuu cacucuccaa cggcguaucu      540

gucuuaacau ucaaaguauu agaccuaaaa aacuacauug acaaacaacu acuaccaauc      600

cuaaacaaac aaucauguuc cauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uauuagaaau aacaagagaa uuuuccguca augcaggagu uacuaccccu      720

gucuccaccu auaugcuaac caauuccgaa cucuuaucau uaauaaacga caugccuauc      780

acaaaugacc aaaaaaaauu aaugagcaac aacguacaaa uaguacgaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguc cuagcauacg uuguacaacu accacuauac      900

ggagucauag auaccccaug cuggaaacuc cauacaagcc cacuaugcac uacaaacaca      960

aaagaaggcu cuaauauaug ucuaacaaga acagaccgag gaugguacug cgauaaugcc     1020

ggcucagucu cauucuuucc gcaagccgaa acuuguaaag uacaaaguaa cagaguauuu     1080

ugugacacca ugaacucaag aacccuccca agcgaaguca aucuaugcaa cguugauaua     1140

uucaauccca aauacgacug caaaaucaug accucaaaaa cagacgucag cucauccguu     1200

auaacaucac uaggagccau cguaucuugc uauggaaaaa caaaaugcac agcaagcaau     1260

aaaaacagag gcauaauaaa aacauucuca aauggaugcg acuacguauc aaacaaagga     1320

gucgacacag uuuccguagg aaacacuuua uacugcguaa acaaacaaga aggaaaauca     1380

uuauacguca aaggugaacc aauaauaaac uucuacgauc cacuuguauu cccaucagac     1440

gaauuugacg caucaauuuc acaaguaaac gaaaaaauaa accaaucacu cgcauucaua     1500

agaaaaucag augaacuacu acauaacgua aacgcaggaa aauccacaac aaacaucaug     1560

auaacaacca ucauaaucgu aauaaucgua auacuauuau cccuaauugc aguaggauua     1620

cucuuauauu gcaaagcaag aucaacacca guaacccuca guaaagacca acuauccgga     1680

auaaauaaca ucgcauucuc aaacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4908
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4908
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacugcu cauccucaaa      120

gccaacgcca ucaccaccau ucuuaccgcc gucacauucu gcuucgccuc aggccaaaac      180

aucaccgaag aauuuuacca auccacuugu ucagccgucu caaaaggaua ccuaucagcc      240

cuccguaccg gcugguacac cucggucaua acaauagaac ucuccaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaggucaaa cugauaaaac aagaacuuga uaaauacaaa      360

aacgccguca cugaacucca acuccucaug caauccacuc ccgcuacugg cucuggcucc      420

gccaucugcu cuggcgucgc cgucuguaaa guacuccacc ucgaagggga agucaacaaa      480

aucaaaucag cccuccuuag caccaacaag gccgucgucu cccucucaaa cggagucagc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaaacaacu ccugcccauc      600

cuaaauaaac aauccugcuc uaucuccaau aucgaaaccg uuauagaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccaccccu      720

gugucaaccu acaugcucac caacagcgaa cuacucucac ucaucaauga caugcccauc      780

accaacgacc aaaagaaacu cauguccaac aacguccaaa ucguacguca acaauccuac      840

agcaucaugu gcaucauaaa agaagaaguc cucgccuacg ucguccaacu uccccucuac      900

ggcgucauag acacccccug cuggaaacug cauaccucac cccuaugcac caccaacacu      960

aaagaaggcu ccaacaucug ccucacccgc acggaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa acuuguaaag uccaauccaa cagagucuuc     1080

ugcgacacca ugaacucuag aacgcugcca uccgagguaa accuaugcaa cgucgacauc     1140

uucaauccca aauacgacug caagaucaug accucaaaaa ccgacguauc cuccucagua     1200

aucaccaguc ucggagcuau cgucuccugc uacggcaaaa ccaaaugcac ggccucuaac     1260

aaaaaccgcg gcaucaucaa aaccuucuca aacggaugcg acuacgucag caacaaaggc     1320

guagauaccg ucucugucgg caacacacug uacugcguaa acaagcaaga aggaaaaucc     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucguuuu ccccucagau     1440

gaauuugacg ccucgauauc acaagucaac gaaaagauaa aucagucccu cgccuucauc     1500

cgaaaauccg acgaacuccu ccacaacguu aacgcaggaa aguccaccac aaacaucaug     1560

auaacuacaa ucauaauagu cauuaucguc auacuccucu cccuaaucgc cguaggccug     1620

cuacucuacu gcaaagcccg cucaaccccc gucacucucu caaaagacca acucuccggc     1680

aucaauaaca ucgccuucuc aaacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  4909
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4909
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4910
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4910
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4911
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4911
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4912
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4912
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgca uucucaaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4913
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4913
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4914
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4914
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcu uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4915
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4915
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauac ucaaagccaa cgcaauaaca acaauauuaa cagccguaac auuuugcuuc      240

gcaucagguc aaaacauaac agaagaguuc uaccaaucca caugcucagc aguaucaaaa      300

ggauauuuaa gugcucuaag aacaggaugg uacacauccg uaauaacaau cgaacuauca      360

aacauaaaag aaaauaaaug uaauggaaca gacgccaaag uaaaauuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguuacugaa uuacaauuau uaaugcaauc aacaccggcc      480

acaggaucug gaucagcaau augcucagga guagcagucu gcaaaguauu acaccuagaa      540

ggggaaguua auaaaaucaa aucagcauua cuauccacca acaaagcggu aguuucacuc      600

uccaacggcg uaucugucuu aacauucaaa guauuagacc uaaaaaacua cauugacaaa      660

caacuacuac caauccuaaa caaacaauca uguuccauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuauua gaaauaacaa gagaauuuuc cgucaaugca      780

ggaguuacua ccccugucuc caccuauaug cuaaccaauu ccgaacucuu aucauuaaua      840

aacgacaugc cuaucacaaa ugaccaaaaa aaauuaauga gcaacaacgu acaaauagua      900

cgacaacaau cauacucaau caugugcaua auaaaagaag aaguccuagc auacguugua      960

caacuaccac uauacggagu cauagauacc ccaugcugga aacuccauac aagcccacua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa caagaacaga ccgaggaugg     1080

uacugcgaua augccggcuc agucucauuc uuuccgcaag ccgaaacuug uaaaguacaa     1140

aguaacagag uauuuuguga caccaugaac ucaagaaccc ucccaagcga agucaaucua     1200

ugcaacguug auauauucaa ucccaaauac gacugcaaaa ucaugaccuc aaaaacagac     1260

gucagcucau ccguuauaac aucacuagga gccaucguau cuugcuaugg aaaaacaaaa     1320

ugcacagcaa gcaauaaaaa cagaggcaua auaaaaacau ucucaaaugg augcgacuac     1380

guaucaaaca aaggagucga cacaguuucc guaggaaaca cuuuauacug cguaaacaaa     1440

caagaaggaa aaucauuaua cgucaaaggu gaaccaauaa uaaacuucua cgauccacuu     1500

guauucccau cagacgaauu ugacgcauca auuucacaag uaaacgaaaa aauaaaccaa     1560

ucacucgcau ucauaagaaa aucagaugaa cuacuacaua acguaaacgc aggaaaaucc     1620

acaacaaaca ucaugauaac aaccaucaua aucguaauaa ucguaauacu auuaucccua     1680

auugcaguag gauuacucuu auauugcaaa gcaagaucaa caccaguaac ccucaguaaa     1740

gaccaacuau ccggaauaaa uaacaucgca uucucaaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4916
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4916
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cugcucaucc ucaaagccaa cgccaucacc accauucuua ccgccgucac auucugcuuc      240

gccucaggcc aaaacaucac cgaagaauuu uaccaaucca cuuguucagc cgucucaaaa      300

ggauaccuau cagcccuccg uaccggcugg uacaccucgg ucauaacaau agaacucucc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaagg ucaaacugau aaaacaagaa      420

cuugauaaau acaaaaacgc cgucacugaa cuccaacucc ucaugcaauc cacucccgcu      480

acuggcucug gcuccgccau cugcucuggc gucgccgucu guaaaguacu ccaccucgaa      540

ggggaaguca acaaaaucaa aucagcccuc cuuagcacca acaaggccgu cgucucccuc      600

ucaaacggag ucagcguccu caccuucaag guccucgacc ucaagaacua caucgacaaa      660

caacuccugc ccauccuaaa uaaacaaucc ugcucuaucu ccaauaucga aaccguuaua      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgca      780

ggcgucacca ccccuguguc aaccuacaug cucaccaaca gcgaacuacu cucacucauc      840

aaugacaugc ccaucaccaa cgaccaaaag aaacucaugu ccaacaacgu ccaaaucgua      900

cgucaacaau ccuacagcau caugugcauc auaaaagaag aaguccucgc cuacgucguc      960

caacuucccc ucuacggcgu cauagacacc cccugcugga aacugcauac cucaccccua     1020

ugcaccacca acacuaaaga aggcuccaac aucugccuca cccgcacgga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaacuug uaaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucuagaacgc ugccauccga gguaaaccua     1200

ugcaacgucg acaucuucaa ucccaaauac gacugcaaga ucaugaccuc aaaaaccgac     1260

guauccuccu caguaaucac cagucucgga gcuaucgucu ccugcuacgg caaaaccaaa     1320

ugcacggccu cuaacaaaaa ccgcggcauc aucaaaaccu ucucaaacgg augcgacuac     1380

gucagcaaca aaggcguaga uaccgucucu gucggcaaca cacuguacug cguaaacaag     1440

caagaaggaa aaucccucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

guuuuccccu cagaugaauu ugacgccucg auaucacaag ucaacgaaaa gauaaaucag     1560

ucccucgccu ucauccgaaa auccgacgaa cuccuccaca acguuaacgc aggaaagucc     1620

accacaaaca ucaugauaac uacaaucaua auagucauua ucgucauacu ccucucccua     1680

aucgccguag gccugcuacu cuacugcaaa gcccgcucaa cccccgucac ucucucaaaa     1740

gaccaacucu ccggcaucaa uaacaucgcc uucucaaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  4917
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4917
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4918
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4918
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4919
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4919
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4920
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4920
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgca uucucaaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4921
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4921
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4922
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4922
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcu uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4923
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4923
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauac ucaaagccaa cgcaauaaca acaauauuaa cagccguaac auuuugcuuc      240

gcaucagguc aaaacauaac agaagaguuc uaccaaucca caugcucagc aguaucaaaa      300

ggauauuuaa gugcucuaag aacaggaugg uacacauccg uaauaacaau cgaacuauca      360

aacauaaaag aaaauaaaug uaauggaaca gacgccaaag uaaaauuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguuacugaa uuacaauuau uaaugcaauc aacaccggcc      480

acaggaucug gaucagcaau augcucagga guagcagucu gcaaaguauu acaccuagaa      540

ggggaaguua auaaaaucaa aucagcauua cuauccacca acaaagcggu aguuucacuc      600

uccaacggcg uaucugucuu aacauucaaa guauuagacc uaaaaaacua cauugacaaa      660

caacuacuac caauccuaaa caaacaauca uguuccauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuauua gaaauaacaa gagaauuuuc cgucaaugca      780

ggaguuacua ccccugucuc caccuauaug cuaaccaauu ccgaacucuu aucauuaaua      840

aacgacaugc cuaucacaaa ugaccaaaaa aaauuaauga gcaacaacgu acaaauagua      900

cgacaacaau cauacucaau caugugcaua auaaaagaag aaguccuagc auacguugua      960

caacuaccac uauacggagu cauagauacc ccaugcugga aacuccauac aagcccacua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa caagaacaga ccgaggaugg     1080

uacugcgaua augccggcuc agucucauuc uuuccgcaag ccgaaacuug uaaaguacaa     1140

aguaacagag uauuuuguga caccaugaac ucaagaaccc ucccaagcga agucaaucua     1200

ugcaacguug auauauucaa ucccaaauac gacugcaaaa ucaugaccuc aaaaacagac     1260

gucagcucau ccguuauaac aucacuagga gccaucguau cuugcuaugg aaaaacaaaa     1320

ugcacagcaa gcaauaaaaa cagaggcaua auaaaaacau ucucaaaugg augcgacuac     1380

guaucaaaca aaggagucga cacaguuucc guaggaaaca cuuuauacug cguaaacaaa     1440

caagaaggaa aaucauuaua cgucaaaggu gaaccaauaa uaaacuucua cgauccacuu     1500

guauucccau cagacgaauu ugacgcauca auuucacaag uaaacgaaaa aauaaaccaa     1560

ucacucgcau ucauaagaaa aucagaugaa cuacuacaua acguaaacgc aggaaaaucc     1620

acaacaaaca ucaugauaac aaccaucaua aucguaauaa ucguaauacu auuaucccua     1680

auugcaguag gauuacucuu auauugcaaa gcaagaucaa caccaguaac ccucaguaaa     1740

gaccaacuau ccggaauaaa uaacaucgca uucucaaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4924
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4924
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cugcucaucc ucaaagccaa cgccaucacc accauucuua ccgccgucac auucugcuuc      240

gccucaggcc aaaacaucac cgaagaauuu uaccaaucca cuuguucagc cgucucaaaa      300

ggauaccuau cagcccuccg uaccggcugg uacaccucgg ucauaacaau agaacucucc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaagg ucaaacugau aaaacaagaa      420

cuugauaaau acaaaaacgc cgucacugaa cuccaacucc ucaugcaauc cacucccgcu      480

acuggcucug gcuccgccau cugcucuggc gucgccgucu guaaaguacu ccaccucgaa      540

ggggaaguca acaaaaucaa aucagcccuc cuuagcacca acaaggccgu cgucucccuc      600

ucaaacggag ucagcguccu caccuucaag guccucgacc ucaagaacua caucgacaaa      660

caacuccugc ccauccuaaa uaaacaaucc ugcucuaucu ccaauaucga aaccguuaua      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgca      780

ggcgucacca ccccuguguc aaccuacaug cucaccaaca gcgaacuacu cucacucauc      840

aaugacaugc ccaucaccaa cgaccaaaag aaacucaugu ccaacaacgu ccaaaucgua      900

cgucaacaau ccuacagcau caugugcauc auaaaagaag aaguccucgc cuacgucguc      960

caacuucccc ucuacggcgu cauagacacc cccugcugga aacugcauac cucaccccua     1020

ugcaccacca acacuaaaga aggcuccaac aucugccuca cccgcacgga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaacuug uaaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucuagaacgc ugccauccga gguaaaccua     1200

ugcaacgucg acaucuucaa ucccaaauac gacugcaaga ucaugaccuc aaaaaccgac     1260

guauccuccu caguaaucac cagucucgga gcuaucgucu ccugcuacgg caaaaccaaa     1320

ugcacggccu cuaacaaaaa ccgcggcauc aucaaaaccu ucucaaacgg augcgacuac     1380

gucagcaaca aaggcguaga uaccgucucu gucggcaaca cacuguacug cguaaacaag     1440

caagaaggaa aaucccucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

guuuuccccu cagaugaauu ugacgccucg auaucacaag ucaacgaaaa gauaaaucag     1560

ucccucgccu ucauccgaaa auccgacgaa cuccuccaca acguuaacgc aggaaagucc     1620

accacaaaca ucaugauaac uacaaucaua auagucauua ucgucauacu ccucucccua     1680

aucgccguag gccugcuacu cuacugcaaa gcccgcucaa cccccgucac ucucucaaaa     1740

gaccaacucu ccggcaucaa uaacaucgcc uucucaaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  4925
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4925
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4926
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4926
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggucca ccccggugac ccugagcaag     1740

gaccagcucu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4927
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4927
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4928
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4928
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcucua caccggugac ccugagcaag     1740

gaccagcucu ccggcauaaa caauaucgca uucucaaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4929
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4929
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4930
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4930
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaucca caccugugac ccuuagcaag     1740

gaccagcucu cugggauuaa caauaucgcu uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4931
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4931
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuucuaauac ucaaagccaa cgcaauaaca acaauauuaa cagccguaac auuuugcuuc      240

gcaucagguc aaaacauaac agaagaguuc uaccaaucca caugcucagc aguaucaaaa      300

ggauauuuaa gugcucuaag aacaggaugg uacacauccg uaauaacaau cgaacuauca      360

aacauaaaag aaaauaaaug uaauggaaca gacgccaaag uaaaauuaau caaacaagaa      420

cuagacaaau acaaaaacgc aguuacugaa uuacaauuau uaaugcaauc aacaccggcc      480

acaggaucug gaucagcaau augcucagga guagcagucu gcaaaguauu acaccuagaa      540

ggggaaguua auaaaaucaa aucagcauua cuauccacca acaaagcggu aguuucacuc      600

uccaacggcg uaucugucuu aacauucaaa guauuagacc uaaaaaacua cauugacaaa      660

caacuacuac caauccuaaa caaacaauca uguuccauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuauua gaaauaacaa gagaauuuuc cgucaaugca      780

ggaguuacua ccccugucuc caccuauaug cuaaccaauu ccgaacucuu aucauuaaua      840

aacgacaugc cuaucacaaa ugaccaaaaa aaauuaauga gcaacaacgu acaaauagua      900

cgacaacaau cauacucaau caugugcaua auaaaagaag aaguccuagc auacguugua      960

caacuaccac uauacggagu cauagauacc ccaugcugga aacuccauac aagcccacua     1020

ugcacuacaa acacaaaaga aggcucuaau auaugucuaa caagaacaga ccgaggaugg     1080

uacugcgaua augccggcuc agucucauuc uuuccgcaag ccgaaacuug uaaaguacaa     1140

aguaacagag uauuuuguga caccaugaac ucaagaaccc ucccaagcga agucaaucua     1200

ugcaacguug auauauucaa ucccaaauac gacugcaaaa ucaugaccuc aaaaacagac     1260

gucagcucau ccguuauaac aucacuagga gccaucguau cuugcuaugg aaaaacaaaa     1320

ugcacagcaa gcaauaaaaa cagaggcaua auaaaaacau ucucaaaugg augcgacuac     1380

guaucaaaca aaggagucga cacaguuucc guaggaaaca cuuuauacug cguaaacaaa     1440

caagaaggaa aaucauuaua cgucaaaggu gaaccaauaa uaaacuucua cgauccacuu     1500

guauucccau cagacgaauu ugacgcauca auuucacaag uaaacgaaaa aauaaaccaa     1560

ucacucgcau ucauaagaaa aucagaugaa cuacuacaua acguaaacgc aggaaaaucc     1620

acaacaaaca ucaugauaac aaccaucaua aucguaauaa ucguaauacu auuaucccua     1680

auugcaguag gauuacucuu auauugcaaa gcaagaucaa caccaguaac ccucaguaaa     1740

gaccaacuau ccggaauaaa uaacaucgca uucucaaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4932
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4932
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cugcucaucc ucaaagccaa cgccaucacc accauucuua ccgccgucac auucugcuuc      240

gccucaggcc aaaacaucac cgaagaauuu uaccaaucca cuuguucagc cgucucaaaa      300

ggauaccuau cagcccuccg uaccggcugg uacaccucgg ucauaacaau agaacucucc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaagg ucaaacugau aaaacaagaa      420

cuugauaaau acaaaaacgc cgucacugaa cuccaacucc ucaugcaauc cacucccgcu      480

acuggcucug gcuccgccau cugcucuggc gucgccgucu guaaaguacu ccaccucgaa      540

ggggaaguca acaaaaucaa aucagcccuc cuuagcacca acaaggccgu cgucucccuc      600

ucaaacggag ucagcguccu caccuucaag guccucgacc ucaagaacua caucgacaaa      660

caacuccugc ccauccuaaa uaaacaaucc ugcucuaucu ccaauaucga aaccguuaua      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgca      780

ggcgucacca ccccuguguc aaccuacaug cucaccaaca gcgaacuacu cucacucauc      840

aaugacaugc ccaucaccaa cgaccaaaag aaacucaugu ccaacaacgu ccaaaucgua      900

cgucaacaau ccuacagcau caugugcauc auaaaagaag aaguccucgc cuacgucguc      960

caacuucccc ucuacggcgu cauagacacc cccugcugga aacugcauac cucaccccua     1020

ugcaccacca acacuaaaga aggcuccaac aucugccuca cccgcacgga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaacuug uaaaguccaa     1140

uccaacagag ucuucugcga caccaugaac ucuagaacgc ugccauccga gguaaaccua     1200

ugcaacgucg acaucuucaa ucccaaauac gacugcaaga ucaugaccuc aaaaaccgac     1260

guauccuccu caguaaucac cagucucgga gcuaucgucu ccugcuacgg caaaaccaaa     1320

ugcacggccu cuaacaaaaa ccgcggcauc aucaaaaccu ucucaaacgg augcgacuac     1380

gucagcaaca aaggcguaga uaccgucucu gucggcaaca cacuguacug cguaaacaag     1440

caagaaggaa aaucccucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

guuuuccccu cagaugaauu ugacgccucg auaucacaag ucaacgaaaa gauaaaucag     1560

ucccucgccu ucauccgaaa auccgacgaa cuccuccaca acguuaacgc aggaaagucc     1620

accacaaaca ucaugauaac uacaaucaua auagucauua ucgucauacu ccucucccua     1680

aucgccguag gccugcuacu cuacugcaaa gcccgcucaa cccccgucac ucucucaaaa     1740

gaccaacucu ccggcaucaa uaacaucgcc uucucaaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4933
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4933
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4934
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4934
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1620

aaggaccagc ucuccgggau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4935
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4935
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4936
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4936
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca      900

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc      960

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1020

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1200

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1320

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu cuacaccggu gacccugagc     1620

aaggaccagc ucuccggcau aaacaauauc gcauucucaa acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4937
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4937
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4938
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4938
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu      900

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga      960

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1200

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguauugc aaagccagau ccacaccugu gacccuuagc     1620

aaggaccagc ucucugggau uaacaauauc gcuuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4939
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4939
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuucuaa uacucaaagc caacgcaaua acaacaauau uaacagccgu aacauuuugc      120

uucgcaucag gucaaaacau aacagaagag uucuaccaau ccacaugcuc agcaguauca      180

aaaggauauu uaagugcucu aagaacagga ugguacacau ccguaauaac aaucgaacua      240

ucaaacauaa aagaaaauaa auguaaugga acagacgcca aaguaaaauu aaucaaacaa      300

gaacuagaca aauacaaaaa cgcaguuacu gaauuacaau uauuaaugca aucaacaccg      360

gccacaggau cuggaucagc aauaugcuca ggaguagcag ucugcaaagu auuacaccua      420

gaaggggaag uuaauaaaau caaaucagca uuacuaucca ccaacaaagc gguaguuuca      480

cucuccaacg gcguaucugu cuuaacauuc aaaguauuag accuaaaaaa cuacauugac      540

aaacaacuac uaccaauccu aaacaaacaa ucauguucca uaagcaauau agaaacagua      600

auagaauuuc aacaaaaaaa caacagacua uuagaaauaa caagagaauu uuccgucaau      660

gcaggaguua cuaccccugu cuccaccuau augcuaacca auuccgaacu cuuaucauua      720

auaaacgaca ugccuaucac aaaugaccaa aaaaaauuaa ugagcaacaa cguacaaaua      780

guacgacaac aaucauacuc aaucaugugc auaauaaaag aagaaguccu agcauacguu      840

guacaacuac cacuauacgg agucauagau accccaugcu ggaaacucca uacaagccca      900

cuaugcacua caaacacaaa agaaggcucu aauauauguc uaacaagaac agaccgagga      960

ugguacugcg auaaugccgg cucagucuca uucuuuccgc aagccgaaac uuguaaagua     1020

caaaguaaca gaguauuuug ugacaccaug aacucaagaa cccucccaag cgaagucaau     1080

cuaugcaacg uugauauauu caaucccaaa uacgacugca aaaucaugac cucaaaaaca     1140

gacgucagcu cauccguuau aacaucacua ggagccaucg uaucuugcua uggaaaaaca     1200

aaaugcacag caagcaauaa aaacagaggc auaauaaaaa cauucucaaa uggaugcgac     1260

uacguaucaa acaaaggagu cgacacaguu uccguaggaa acacuuuaua cugcguaaac     1320

aaacaagaag gaaaaucauu auacgucaaa ggugaaccaa uaauaaacuu cuacgaucca     1380

cuuguauucc caucagacga auuugacgca ucaauuucac aaguaaacga aaaaauaaac     1440

caaucacucg cauucauaag aaaaucagau gaacuacuac auaacguaaa cgcaggaaaa     1500

uccacaacaa acaucaugau aacaaccauc auaaucguaa uaaucguaau acuauuaucc     1560

cuaauugcag uaggauuacu cuuauauugc aaagcaagau caacaccagu aacccucagu     1620

aaagaccaac uauccggaau aaauaacauc gcauucucaa acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4940
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4940
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacugcuca uccucaaagc caacgccauc accaccauuc uuaccgccgu cacauucugc      120

uucgccucag gccaaaacau caccgaagaa uuuuaccaau ccacuuguuc agccgucuca      180

aaaggauacc uaucagcccu ccguaccggc ugguacaccu cggucauaac aauagaacuc      240

uccaacauaa aagaaaacaa augcaacggc accgacgcca aggucaaacu gauaaaacaa      300

gaacuugaua aauacaaaaa cgccgucacu gaacuccaac uccucaugca auccacuccc      360

gcuacuggcu cuggcuccgc caucugcucu ggcgucgccg ucuguaaagu acuccaccuc      420

gaaggggaag ucaacaaaau caaaucagcc cuccuuagca ccaacaaggc cgucgucucc      480

cucucaaacg gagucagcgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aaacaacucc ugcccauccu aaauaaacaa uccugcucua ucuccaauau cgaaaccguu      600

auagaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      660

gcaggcguca ccaccccugu gucaaccuac augcucacca acagcgaacu acucucacuc      720

aucaaugaca ugcccaucac caacgaccaa aagaaacuca uguccaacaa cguccaaauc      780

guacgucaac aauccuacag caucaugugc aucauaaaag aagaaguccu cgccuacguc      840

guccaacuuc cccucuacgg cgucauagac acccccugcu ggaaacugca uaccucaccc      900

cuaugcacca ccaacacuaa agaaggcucc aacaucugcc ucacccgcac ggaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac uuguaaaguc     1020

caauccaaca gagucuucug cgacaccaug aacucuagaa cgcugccauc cgagguaaac     1080

cuaugcaacg ucgacaucuu caaucccaaa uacgacugca agaucaugac cucaaaaacc     1140

gacguauccu ccucaguaau caccagucuc ggagcuaucg ucuccugcua cggcaaaacc     1200

aaaugcacgg ccucuaacaa aaaccgcggc aucaucaaaa ccuucucaaa cggaugcgac     1260

uacgucagca acaaaggcgu agauaccguc ucugucggca acacacugua cugcguaaac     1320

aagcaagaag gaaaaucccu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucguuuucc ccucagauga auuugacgcc ucgauaucac aagucaacga aaagauaaau     1440

cagucccucg ccuucauccg aaaauccgac gaacuccucc acaacguuaa cgcaggaaag     1500

uccaccacaa acaucaugau aacuacaauc auaauaguca uuaucgucau acuccucucc     1560

cuaaucgccg uaggccugcu acucuacugc aaagcccgcu caacccccgu cacucucuca     1620

aaagaccaac ucuccggcau caauaacauc gccuucucaa acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  4941
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4941
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc cuguccaagg     1620

accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4942
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4942
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug caccucgagg      420

gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug gucucccuca      480

gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac cggggguggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag gucaaccugu     1080

gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg aagaccaagu     1200

gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg ugcgacuacg     1260

ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc gucaacaagc     1320

aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg gggaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg ccuccugcug uacugcaagg cccgguccac cccggugacc cugagcaagg     1620

accagcucuc cgggaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4943
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4943
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc cucuccaagg     1620

accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4944
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4944
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug caccucgagg      420

gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug gucucucuca      480

gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac auugauaaac      540

aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu gucaacgccg      660

gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug agccucauca      720

acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc cagaucguuc      780

gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg uauguagugc      840

aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca agcccacugu      900

gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau cguggcuggu      960

acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu aagguucagu     1020

caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag gucaaccucu     1080

gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc aaaacagacg     1140

uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu aagacuaaau     1200

guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg ugcgauuaug     1260

ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu guuaacaagc     1320

aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac gacccuuugg     1380

uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa aucaaccaga     1440

gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc ggaaagucaa     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaagucuca     1560

ucgcggucgg ccugcuuuug uauugcaaag cccgcucuac accggugacc cugagcaagg     1620

accagcucuc cggcauaaac aauaucgcau ucucaaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4945
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4945
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc cugagcaagg     1620

accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4946
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4946
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc caccuggagg      420

gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc gugucccuca      480

gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac auugauaaac      540

aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc gugaacgcug      660

gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc ucucugauca      720

acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug cagaucguga      780

gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc uaugugguuc      840

aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg ucuccucucu      900

gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau cgcggauggu      960

acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu aaggugcaga     1020

gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag gugaaucucu     1080

gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc aaaacagacg     1140

uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga aagacaaaau     1200

guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg ugcgauuaug     1260

uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu guuaacaagc     1320

aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac gacccucucg     1380

ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa auuaaccaga     1440

gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu ggaaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucucuga     1560

ucgccguggg ccuccugcug uauugcaaag ccagauccac accugugacc cuuagcaagg     1620

accagcucuc ugggauuaac aauaucgcuu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4947
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4947
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uucuaauacu caaagccaac gcaauaacaa caauauuaac agccguaaca uuuugcuucg      120

caucagguca aaacauaaca gaagaguucu accaauccac augcucagca guaucaaaag      180

gauauuuaag ugcucuaaga acaggauggu acacauccgu aauaacaauc gaacuaucaa      240

acauaaaaga aaauaaaugu aauggaacag acgccaaagu aaaauuaauc aaacaagaac      300

uagacaaaua caaaaacgca guuacugaau uacaauuauu aaugcaauca acaccggcca      360

caggaucugg aucagcaaua ugcucaggag uagcagucug caaaguauua caccuagaag      420

gggaaguuaa uaaaaucaaa ucagcauuac uauccaccaa caaagcggua guuucacucu      480

ccaacggcgu aucugucuua acauucaaag uauuagaccu aaaaaacuac auugacaaac      540

aacuacuacc aauccuaaac aaacaaucau guuccauaag caauauagaa acaguaauag      600

aauuucaaca aaaaaacaac agacuauuag aaauaacaag agaauuuucc gucaaugcag      660

gaguuacuac cccugucucc accuauaugc uaaccaauuc cgaacucuua ucauuaauaa      720

acgacaugcc uaucacaaau gaccaaaaaa aauuaaugag caacaacgua caaauaguac      780

gacaacaauc auacucaauc augugcauaa uaaaagaaga aguccuagca uacguuguac      840

aacuaccacu auacggaguc auagauaccc caugcuggaa acuccauaca agcccacuau      900

gcacuacaaa cacaaaagaa ggcucuaaua uaugucuaac aagaacagac cgaggauggu      960

acugcgauaa ugccggcuca gucucauucu uuccgcaagc cgaaacuugu aaaguacaaa     1020

guaacagagu auuuugugac accaugaacu caagaacccu cccaagcgaa gucaaucuau     1080

gcaacguuga uauauucaau cccaaauacg acugcaaaau caugaccuca aaaacagacg     1140

ucagcucauc cguuauaaca ucacuaggag ccaucguauc uugcuaugga aaaacaaaau     1200

gcacagcaag caauaaaaac agaggcauaa uaaaaacauu cucaaaugga ugcgacuacg     1260

uaucaaacaa aggagucgac acaguuuccg uaggaaacac uuuauacugc guaaacaaac     1320

aagaaggaaa aucauuauac gucaaaggug aaccaauaau aaacuucuac gauccacuug     1380

uauucccauc agacgaauuu gacgcaucaa uuucacaagu aaacgaaaaa auaaaccaau     1440

cacucgcauu cauaagaaaa ucagaugaac uacuacauaa cguaaacgca ggaaaaucca     1500

caacaaacau caugauaaca accaucauaa ucguaauaau cguaauacua uuaucccuaa     1560

uugcaguagg auuacucuua uauugcaaag caagaucaac accaguaacc cucaguaaag     1620

accaacuauc cggaauaaau aacaucgcau ucucaaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4948
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4948
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

ugcucauccu caaagccaac gccaucacca ccauucuuac cgccgucaca uucugcuucg      120

ccucaggcca aaacaucacc gaagaauuuu accaauccac uuguucagcc gucucaaaag      180

gauaccuauc agcccuccgu accggcuggu acaccucggu cauaacaaua gaacucucca      240

acauaaaaga aaacaaaugc aacggcaccg acgccaaggu caaacugaua aaacaagaac      300

uugauaaaua caaaaacgcc gucacugaac uccaacuccu caugcaaucc acucccgcua      360

cuggcucugg cuccgccauc ugcucuggcg ucgccgucug uaaaguacuc caccucgaag      420

gggaagucaa caaaaucaaa ucagcccucc uuagcaccaa caaggccguc gucucccucu      480

caaacggagu cagcguccuc accuucaagg uccucgaccu caagaacuac aucgacaaac      540

aacuccugcc cauccuaaau aaacaauccu gcucuaucuc caauaucgaa accguuauag      600

aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc gucaacgcag      660

gcgucaccac cccuguguca accuacaugc ucaccaacag cgaacuacuc ucacucauca      720

augacaugcc caucaccaac gaccaaaaga aacucauguc caacaacguc caaaucguac      780

gucaacaauc cuacagcauc augugcauca uaaaagaaga aguccucgcc uacgucgucc      840

aacuuccccu cuacggcguc auagacaccc ccugcuggaa acugcauacc ucaccccuau      900

gcaccaccaa cacuaaagaa ggcuccaaca ucugccucac ccgcacggac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaacuugu aaaguccaau     1020

ccaacagagu cuucugcgac accaugaacu cuagaacgcu gccauccgag guaaaccuau     1080

gcaacgucga caucuucaau cccaaauacg acugcaagau caugaccuca aaaaccgacg     1140

uauccuccuc aguaaucacc agucucggag cuaucgucuc cugcuacggc aaaaccaaau     1200

gcacggccuc uaacaaaaac cgcggcauca ucaaaaccuu cucaaacgga ugcgacuacg     1260

ucagcaacaa aggcguagau accgucucug ucggcaacac acuguacugc guaaacaagc     1320

aagaaggaaa aucccucuac guaaaaggcg aacccaucau caacuucuac gacccccucg     1380

uuuuccccuc agaugaauuu gacgccucga uaucacaagu caacgaaaag auaaaucagu     1440

cccucgccuu cauccgaaaa uccgacgaac uccuccacaa cguuaacgca ggaaagucca     1500

ccacaaacau caugauaacu acaaucauaa uagucauuau cgucauacuc cucucccuaa     1560

ucgccguagg ccugcuacuc uacugcaaag cccgcucaac ccccgucacu cucucaaaag     1620

accaacucuc cggcaucaau aacaucgccu ucucaaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  4949
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1) R7458

<400>  4949
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

agcaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccggacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc aagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccggagc     1560

acgcccguca cccuguccaa ggaccagcug agcggcauca acaacaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4950
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt1)

<400>  4950
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccggcagc ggguccgcca ucugcagcgg cguggccgug      360

ugcaaggucc ugcaccucga gggcgaggug aacaagauca aguccgcgcu gcugagcacc      420

aacaaggccg uggucucccu cagcaacggg guguccgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcagag cugcuccauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggcgucacc acgcccguga gcaccuacau gcucaccaac      660

agcgagcugc ugucccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccc cuguacgggg ugaucgacac gccgugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggcuccaa caucugccug      900

acccgcaccg accgggggug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccggacc     1020

cuccccuccg aggucaaccu gugcaacgug gacaucuuca acccgaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg cgccaucgug     1140

uccugcuacg ggaagaccaa gugcaccgcc agcaacaaga accggggcau caucaagacc     1200

uucuccaacg ggugcgacua cgugagcaac aagggcgucg acacggugag cgugggcaac     1260

acccucuacu gcgucaacaa gcaggagggg aagucccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cggggaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug ggccuccugc uguacugcaa ggcccggucc     1560

accccgguga cccugagcaa ggaccagcuc uccgggauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4951
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt2)

<400>  4951
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

uccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccgcacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc aagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcucc     1560

acccccguca cccucuccaa ggaccagcuc uccggcauca acaacaucgc cuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4952
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt3)

<400>  4952
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccggcucg gggucagcua uauguagcgg aguggcaguc      360

ugcaaggugu ugcaccucga gggcgaaguu aacaaaauca agagugcccu gcuguccacg      420

aauaaagcug uggucucucu cagcaacggu guguccguau uaacuuuuaa gguucuggac      480

cuuaagaauu acauugauaa acaauugcug ccuauccuaa acaagcaguc auguaguauu      540

agcaauaucg agaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuuu cugucaacgc cggggugacu accccagugu ccacauauau gcuuaccaau      660

ucagaacugu ugagccucau caacgacaug ccgauuacga acgaucaaaa gaaacugaug      720

aguaauaacg uccagaucgu ucgccagcag ucuuacucca ucaugugcau uauaaaggag      780

gaaguguuag cguauguagu gcaacugccc cucuacggag ucaucgacac uccuuguugg      840

aaacuucaua caagcccacu gugcaccacu aauacaaagg agggcucgaa cauuuguuug      900

acccgaacgg aucguggcug guacugcgac aaugcagggu cuguguccuu cuuuccccag      960

gccgaaaccu guaagguuca gucaaacaga guguucugcg auacaaugaa uaguagaacu     1020

cugccuagcg aggucaaccu cugcaaugug gacaucuuua acccaaaaua ugauuguaag     1080

auaaugaccu ccaaaacaga cguaucuagc ucaguuauua ccagucuggg agcuaucgug     1140

uccugcuacg guaagacuaa auguacagcc agcaauaaga acaggggcau cauuaagacc     1200

uucucuaaug ggugcgauua ugucucaaac aaaggagugg acacugucag ugugggcaau     1260

acgcuuuacu guguuaacaa gcaagagggu aaaagccugu augugaaggg ggaacccauc     1320

auuaacuuuu acgacccuuu gguauuccca uccgaugagu uugacgcauc uauaucgcag     1380

gucaaugaga aaaucaacca gagccucgcu uucauucgga aguccgauga acuguuacac     1440

aaugugaacg ccggaaaguc aacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaagucu caucgcgguc ggccugcuuu uguauugcaa agcccgcucu     1560

acaccgguga cccugagcaa ggaccagcuc uccggcauaa acaauaucgc auucucaaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4953
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt4)

<400>  4953
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagcagaacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc aagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagaagc     1560

acccccguga cccugagcaa ggaccagcug agcggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4954
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt5)

<400>  4954
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacagggucu ggaagcgcua uuuguuccgg cgucgccgug      360

ugcaagguuc uccaccugga gggggaagug aacaaaauca agagcgcgcu ucugucuacc      420

aauaaagccg ucgugucccu cagcaacgga guuucugugc ugacauuuaa gguccuugac      480

cugaagaauu acauugauaa acaacuccug ccuauccuga acaagcaguc cuguagcauu      540

ucuaauaucg agaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuuu ccgugaacgc uggcgucaca accccgguua gcacauauau gcuuaccaau      660

uccgaacugc ucucucugau caacgacaug cccauuacca acgaucaaaa gaaacuuaug      720

agcaauaacg ugcagaucgu gagacagcag uccuacagca uuaugugcau cauuaaggag      780

gaaguccugg ccuauguggu ucaacucccu cuguacggcg ugaucgacac acccuguugg      840

aaacugcaua cgucuccucu cugcaccaca aauaccaagg agggguccaa caucugucug      900

acacggaccg aucgcggaug guacugcgac aaugcuggca gcgucucuuu cuuuccccag      960

gccgaaacgu guaaggugca gagcaacaga guuuucugcg auacaaugaa cuccagaacc     1020

cugccuucug aggugaaucu cugcaauguc gacauuuuua acccgaaaua ugauuguaag     1080

aucaugacca gcaaaacaga cguguccagc ucugucauua ccucccuggg ggcgaucgug     1140

agcugcuacg gaaagacaaa auguacggcc ucuaauaaga accggggcau uaucaagacc     1200

uucuccaaug ggugcgauua uguuagcaac aaaggagugg acacagucuc cgugggcaau     1260

acccuuuacu guguuaacaa gcaagagggc aaaucucugu augugaaggg ggaacccauc     1320

auuaacuuuu acgacccucu cgucuucccc agcgaugagu uugacgcuuc caucucucag     1380

gugaaugaga aaauuaacca gagccuggcc uucauccgca aguccgauga acugcuccac     1440

aaugugaacg cuggaaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucucu gaucgccgug ggccuccugc uguauugcaa agccagaucc     1560

acaccuguga cccuuagcaa ggaccagcuc ucugggauua acaauaucgc uuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4955
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt6)

<400>  4955
gggagaaagc uuaccaugga acuucuaaua cucaaagcca acgcaauaac aacaauauua       60

acagccguaa cauuuugcuu cgcaucaggu caaaacauaa cagaagaguu cuaccaaucc      120

acaugcucag caguaucaaa aggauauuua agugcucuaa gaacaggaug guacacaucc      180

guaauaacaa ucgaacuauc aaacauaaaa gaaaauaaau guaauggaac agacgccaaa      240

guaaaauuaa ucaaacaaga acuagacaaa uacaaaaacg caguuacuga auuacaauua      300

uuaaugcaau caacaccggc cacaggaucu ggaucagcaa uaugcucagg aguagcaguc      360

ugcaaaguau uacaccuaga aggggaaguu aauaaaauca aaucagcauu acuauccacc      420

aacaaagcgg uaguuucacu cuccaacggc guaucugucu uaacauucaa aguauuagac      480

cuaaaaaacu acauugacaa acaacuacua ccaauccuaa acaaacaauc auguuccaua      540

agcaauauag aaacaguaau agaauuucaa caaaaaaaca acagacuauu agaaauaaca      600

agagaauuuu ccgucaaugc aggaguuacu accccugucu ccaccuauau gcuaaccaau      660

uccgaacucu uaucauuaau aaacgacaug ccuaucacaa augaccaaaa aaaauuaaug      720

agcaacaacg uacaaauagu acgacaacaa ucauacucaa ucaugugcau aauaaaagaa      780

gaaguccuag cauacguugu acaacuacca cuauacggag ucauagauac cccaugcugg      840

aaacuccaua caagcccacu augcacuaca aacacaaaag aaggcucuaa uauaugucua      900

acaagaacag accgaggaug guacugcgau aaugccggcu cagucucauu cuuuccgcaa      960

gccgaaacuu guaaaguaca aaguaacaga guauuuugug acaccaugaa cucaagaacc     1020

cucccaagcg aagucaaucu augcaacguu gauauauuca aucccaaaua cgacugcaaa     1080

aucaugaccu caaaaacaga cgucagcuca uccguuauaa caucacuagg agccaucgua     1140

ucuugcuaug gaaaaacaaa augcacagca agcaauaaaa acagaggcau aauaaaaaca     1200

uucucaaaug gaugcgacua cguaucaaac aaaggagucg acacaguuuc cguaggaaac     1260

acuuuauacu gcguaaacaa acaagaagga aaaucauuau acgucaaagg ugaaccaaua     1320

auaaacuucu acgauccacu uguauuccca ucagacgaau uugacgcauc aauuucacaa     1380

guaaacgaaa aaauaaacca aucacucgca uucauaagaa aaucagauga acuacuacau     1440

aacguaaacg caggaaaauc cacaacaaac aucaugauaa caaccaucau aaucguaaua     1500

aucguaauac uauuaucccu aauugcagua ggauuacucu uauauugcaa agcaagauca     1560

acaccaguaa cccucaguaa agaccaacua uccggaauaa auaacaucgc auucucaaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4956
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut4 (opt11)

<400>  4956
gggagaaagc uuaccaugga acugcucauc cucaaagcca acgccaucac caccauucuu       60

accgccguca cauucugcuu cgccucaggc caaaacauca ccgaagaauu uuaccaaucc      120

acuuguucag ccgucucaaa aggauaccua ucagcccucc guaccggcug guacaccucg      180

gucauaacaa uagaacucuc caacauaaaa gaaaacaaau gcaacggcac cgacgccaag      240

gucaaacuga uaaaacaaga acuugauaaa uacaaaaacg ccgucacuga acuccaacuc      300

cucaugcaau ccacucccgc uacuggcucu ggcuccgcca ucugcucugg cgucgccguc      360

uguaaaguac uccaccucga aggggaaguc aacaaaauca aaucagcccu ccuuagcacc      420

aacaaggccg ucgucucccu cucaaacgga gucagcgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa acaacuccug cccauccuaa auaaacaauc cugcucuauc      540

uccaauaucg aaaccguuau agaguuccaa cagaaaaaca accgacuccu cgaaaucacc      600

cgcgaguucu ccgucaacgc aggcgucacc accccugugu caaccuacau gcucaccaac      660

agcgaacuac ucucacucau caaugacaug cccaucacca acgaccaaaa gaaacucaug      720

uccaacaacg uccaaaucgu acgucaacaa uccuacagca ucaugugcau cauaaaagaa      780

gaaguccucg ccuacgucgu ccaacuuccc cucuacggcg ucauagacac ccccugcugg      840

aaacugcaua ccucaccccu augcaccacc aacacuaaag aaggcuccaa caucugccuc      900

acccgcacgg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccaa      960

gccgaaacuu guaaagucca auccaacaga gucuucugcg acaccaugaa cucuagaacg     1020

cugccauccg agguaaaccu augcaacguc gacaucuuca aucccaaaua cgacugcaag     1080

aucaugaccu caaaaaccga cguauccucc ucaguaauca ccagucucgg agcuaucguc     1140

uccugcuacg gcaaaaccaa augcacggcc ucuaacaaaa accgcggcau caucaaaacc     1200

uucucaaacg gaugcgacua cgucagcaac aaaggcguag auaccgucuc ugucggcaac     1260

acacuguacu gcguaaacaa gcaagaagga aaaucccucu acguaaaagg cgaacccauc     1320

aucaacuucu acgacccccu cguuuucccc ucagaugaau uugacgccuc gauaucacaa     1380

gucaacgaaa agauaaauca gucccucgcc uucauccgaa aauccgacga acuccuccac     1440

aacguuaacg caggaaaguc caccacaaac aucaugauaa cuacaaucau aauagucauu     1500

aucgucauac uccucucccu aaucgccgua ggccugcuac ucuacugcaa agcccgcuca     1560

acccccguca cucucucaaa agaccaacuc uccggcauca auaacaucgc cuucucaaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  4957
<211>  514
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4957

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Cys Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Ser 
                165                 170                 175     


Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Arg Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Cys Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg 
        


<210>  4958
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4958
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucugc agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      540

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaaccgg gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacugcgug     1260

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc gguga                     1545


<210>  4959
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4959
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccaccg gcagcggguc cgccaucugc agcggcgugg ccgugugcaa gguccugcac      360

cucgagggcg aggugaacaa gaucaagucc gcgcugcuga gcaccaacaa ggccgugguc      420

ucccucagca acgggguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      480

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      600

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ucccccugua cggggugauc gacacgccgu gcuggaagcu gcacaccagc      840

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      900

gggugguacu gcgacaacgc cggcuccgug agcuucuucc cccaggcgga gaccugcaag      960

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1020

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1140

accaagugca ccgccagcaa caagaaccgg ggcaucauca agaccuucuc caacgggugc     1200

gacuacguga gcaacaaggg cgucgacacg gugagcgugg gcaacacccu cuacugcguc     1260

aacaagcagg aggggaaguc ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagagc gacgagcugc ugcacaacgu gaacgcgggg     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1500

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguga                     1545


<210>  4960
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4960
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucugc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      540

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaaccgc ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacugcguc     1260

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuga                     1545


<210>  4961
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4961
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccaccg gcucgggguc agcuauaugu agcggagugg cagucugcaa gguguugcac      360

cucgagggcg aaguuaacaa aaucaagagu gcccugcugu ccacgaauaa agcugugguc      420

ucucucagca acgguguguc cguauuaacu uuuaagguuc uggaccuuaa gaauuacauu      480

gauaaacaau ugcugccuau ccuaaacaag cagucaugua guauuagcaa uaucgagacc      540

gugauagagu uccagcagaa aaacaauagg cuccuggaaa uuacacggga guuuucuguc      600

aacgccgggg ugacuacccc aguguccaca uauaugcuua ccaauucaga acuguugagc      660

cucaucaacg acaugccgau uacgaacgau caaaagaaac ugaugaguaa uaacguccag      720

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcguau      780

guagugcaac ugccccucua cggagucauc gacacuccuu guuggaaacu ucauacaagc      840

ccacugugca ccacuaauac aaaggagggc ucgaacauuu guuugacccg aacggaucgu      900

ggcugguacu gcgacaaugc agggucugug uccuucuuuc cccaggccga aaccuguaag      960

guucagucaa acagaguguu cugcgauaca augaauagua gaacucugcc uagcgagguc     1020

aaccucugca auguggacau cuuuaaccca aaauaugauu guaagauaau gaccuccaaa     1080

acagacguau cuagcucagu uauuaccagu cugggagcua ucguguccug cuacgguaag     1140

acuaaaugua cagccagcaa uaagaacagg ggcaucauua agaccuucuc uaaugggugc     1200

gauuaugucu caaacaaagg aguggacacu gucagugugg gcaauacgcu uuacuguguu     1260

aacaagcaag aggguaaaag ccuguaugug aagggggaac ccaucauuaa cuuuuacgac     1320

ccuuugguau ucccauccga ugaguuugac gcaucuauau cgcaggucaa ugagaaaauc     1380

aaccagagcc ucgcuuucau ucggaagucc gaugaacugu uacacaaugu gaacgccgga     1440

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1500

agucucaucg cggucggccu gcuuuuguau ugcaaagccc gcuga                     1545


<210>  4962
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4962
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucugc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      540

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaga ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacugcgug     1260

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gauga                     1545


<210>  4963
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4963
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacag ggucuggaag cgcuauuugu uccggcgucg ccgugugcaa gguucuccac      360

cuggaggggg aagugaacaa aaucaagagc gcgcuucugu cuaccaauaa agccgucgug      420

ucccucagca acggaguuuc ugugcugaca uuuaaggucc uugaccugaa gaauuacauu      480

gauaaacaac uccugccuau ccugaacaag caguccugua gcauuucuaa uaucgagacc      540

gugauugagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuuccgug      600

aacgcuggcg ucacaacccc gguuagcaca uauaugcuua ccaauuccga acugcucucu      660

cugaucaacg acaugcccau uaccaacgau caaaagaaac uuaugagcaa uaacgugcag      720

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggccuau      780

gugguucaac ucccucugua cggcgugauc gacacacccu guuggaaacu gcauacgucu      840

ccucucugca ccacaaauac caaggagggg uccaacaucu gucugacacg gaccgaucgc      900

ggaugguacu gcgacaaugc uggcagcguc ucuuucuuuc cccaggccga aacguguaag      960

gugcagagca acagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1020

aaucucugca augucgacau uuuuaacccg aaauaugauu guaagaucau gaccagcaaa     1080

acagacgugu ccagcucugu cauuaccucc cugggggcga ucgugagcug cuacggaaag     1140

acaaaaugua cggccucuaa uaagaaccgg ggcauuauca agaccuucuc caaugggugc     1200

gauuauguua gcaacaaagg aguggacaca gucuccgugg gcaauacccu uuacuguguu     1260

aacaagcaag agggcaaauc ucuguaugug aagggggaac ccaucauuaa cuuuuacgac     1320

ccucucgucu uccccagcga ugaguuugac gcuuccaucu cucaggugaa ugagaaaauu     1380

aaccagagcc uggccuucau ccgcaagucc gaugaacugc uccacaaugu gaacgcugga     1440

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1500

ucucugaucg ccgugggccu ccugcuguau ugcaaagcca gauga                     1545


<210>  4964
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4964
auggaacuuu uaauacuaaa agcuaacgcc auaaccacua uacuaacagc agucacauuc       60

ugcuucgcau caggccaaaa cauaaccgaa gaauuuuacc aauccacuug uucagcaguc      120

uccaaaggau auuuauccgc acuucguaca ggaugguaua caucaguaau aacaauagaa      180

cucuccaaca uaaaagaaaa uaaaugcaac ggcaccgacg caaaaguaaa acucaucaaa      240

caagaauuag acaaauacaa gaacgccgua acagaacuac aauuacuaau gcaaucaaca      300

cccgccacag gaucaggauc ugcaauaugc ucuggaguag caguaugcaa aguauuacac      360

cuagaaggag aaguaaacaa aaucaaaagc gcacuacuau ccacaaacaa agcuguagua      420

ucacuaucaa acggaguauc aguauuaacu uucaaaguac uugaucuaaa aaacuacaua      480

gacaaacaac uacuacccau auuaaacaaa caaucaugcu caauaagcaa uauagaaaca      540

guaauagaau uucaacaaaa aaacaacaga cuacuagaaa ucacaaggga auuuucagua      600

aaugccggug uuacaacccc aguaucaaca uacaugcuaa cuaacucaga acuacuaucc      660

uuaauaaacg auaugccaau aacaaacgau caaaaaaaac uaauguccaa caacguacaa      720

auaguaagac aacaaucaua cucaaucaug ugcauuauaa aagaagaagu cuuagcauac      780

guaguacaau uaccacuaua cgguguaaua gauacaccau guuggaaauu acacacaagc      840

ccacuaugca caacuaacac aaaagaaggc ucaaauauau guuuaacaag aacagaccga      900

gguugguacu gcgacaaugc aggaucagua ucauucuuuc cacaagcaga aacauguaaa      960

guucaaucca acagaguauu cugcgacaca augaacucca gaacacuacc uucagaagua     1020

aaccucugua acguagacau auuuaauccc aaguacgacu gcaaaauaau gacaucgaaa     1080

acagacguaa gcuccucagu gauaacaucc cucggcgcca ucguauccug uuacgguaaa     1140

acuaaaugua ccgccucaaa caaaaaccgc gguauuauaa aaacuuuuuc uaauggcugc     1200

gauuacguaa gcaacaaagg cgucgacaca guuuccguag gaaacacacu auacugcgua     1260

aacaaacaag aagguaaauc ucuauacgua aaaggagaac caauaauaaa uuucuaugau     1320

ccuuuaguau ucccauccga ugaauuugac gccucuaucu cacaagucaa cgaaaaaaua     1380

aaucaaucau uagcauucau acgaaaauca gacgaacuac uacacaacgu aaacgcagga     1440

aaaucaacaa ccaacauaau gauaaccaca auaauaauag uuauuauagu gauacuauua     1500

uccuuaauug cagucggacu auuauuauac uguaaagcac gcuaa                     1545


<210>  4965
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut4

<400>  4965
auggaacucc ucauccucaa agccaaugcc aucaccacaa uccugacagc aguaaccuuc       60

ugcuucgcau ccggacaaaa caucaccgaa gaauuuuacc agucaaccug cuccgcuguc      120

ucaaaaggcu accucucagc ccuucgcacc ggcugguaca ccucggucau aacaauagaa      180

cucuccaaua ucaaagaaaa caaaugcaac ggcacugacg ccaagguaaa acucaucaaa      240

caggaacucg auaaauacaa gaacgccgua acagaacuac aacuacucau gcaaucaaca      300

ccggccaccg gcuccgguuc cgccauaugc uccggagugg ccgugugcaa gguccuccac      360

cuugaagggg aaguuaacaa aaucaaauca gcccuccucu ccacuaacaa agccguagua      420

ucccuaagca acgguguauc cguccucacc uucaaaguac uagaccuaaa gaauuauauc      480

gacaaacaac uccuccccau acucaacaaa caauccugcu ccauaagcaa caucgaaaca      540

gucaucgagu uccagcagaa aaacaaccga cuccucgaaa uaacccgcga guucucaguc      600

aacgccggag ucaccacacc cgucagcacc uacaugcuga ccaacuccga acuccucucc      660

uuaaucaaug acaugcccau caccaaugac caaaagaaac ucaugucaaa caacguccaa      720

auaguacgcc aacaauccua cuccaucaug ugcaucauaa aagaagaagu acucgccuac      780

gucguccaac ucccccucua cggcguaauc gacacccccu gcuggaaacu acacacaagc      840

ccccucugca ccacaaacac uaaagagggc uccaacaucu gucuaacccg caccgaucga      900

ggcugguacu gcgacaacgc cggaucuguc ucauucuucc cccaagccga aaccugcaaa      960

guccaaucca accgcgucuu cugcgacacc augaacucga gaacccuccc uuccgaaguc     1020

aaccuaugca acgucgacau uuucaacccc aaauacgacu gcaaaaucau gaccucgaaa     1080

accgacguau cauccagcgu caucaccagc cuaggcgcaa ucgugagcug cuacggcaaa     1140

accaaaugca ccgcgagcaa uaaaaaccgc gggaucauca aaacuuucuc caacggcugc     1200

gacuacgucu ccaacaaggg agucgauacc gucuccguag gcaacacccu cuacugcguc     1260

aacaaacaag aaggcaaauc acuauacgua aaaggcgagc caaucauaaa cuucuacgac     1320

ccucuaguuu ucccauccga cgaguucgac gcuagcaucu cccaagucaa cgagaaaauc     1380

aaccaauccc ucgcauucau ccgcaaaucc gacgaacucc uccacaacgu aaacgcaggc     1440

aaaucaacua cuaauauaau gaucacaacc aucauaauag ucauaaucgu aauccuccua     1500

ucccucaucg ccgucggacu acugcucuac ugcaaagccc gcuaa                     1545


<210>  4966
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4966
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4967
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4967
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4968
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  4968
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4969
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  4969
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4970
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  4970
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4971
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  4971
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4972
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  4972
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacuaaaagc uaacgccaua accacuauac      120

uaacagcagu cacauucugc uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau      180

ccacuuguuc agcagucucc aaaggauauu uauccgcacu ucguacagga ugguauacau      240

caguaauaac aauagaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcaa      300

aaguaaaacu caucaaacaa gaauuagaca aauacaagaa cgccguaaca gaacuacaau      360

uacuaaugca aucaacaccc gccacaggau caggaucugc aauaugcucu ggaguagcag      420

uaugcaaagu auuacaccua gaaggagaag uaaacaaaau caaaagcgca cuacuaucca      480

caaacaaagc uguaguauca cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug      540

aucuaaaaaa cuacauagac aaacaacuac uacccauauu aaacaaacaa ucaugcucaa      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua cuagaaauca      660

caagggaauu uucaguaaau gccgguguua caaccccagu aucaacauac augcuaacua      720

acucagaacu acuauccuua auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauacuc aaucaugugc auuauaaaag      840

aagaagucuu agcauacgua guacaauuac cacuauacgg uguaauagau acaccauguu      900

ggaaauuaca cacaagccca cuaugcacaa cuaacacaaa agaaggcuca aauauauguu      960

uaacaagaac agaccgaggu ugguacugcg acaaugcagg aucaguauca uucuuuccac     1020

aagcagaaac auguaaaguu caauccaaca gaguauucug cgacacaaug aacuccagaa     1080

cacuaccuuc agaaguaaac cucuguaacg uagacauauu uaaucccaag uacgacugca     1140

aaauaaugac aucgaaaaca gacguaagcu ccucagugau aacaucccuc ggcgccaucg     1200

uauccuguua cgguaaaacu aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa     1260

cuuuuucuaa uggcugcgau uacguaagca acaaaggcgu cgacacaguu uccguaggaa     1320

acacacuaua cugcguaaac aaacaagaag guaaaucucu auacguaaaa ggagaaccaa     1380

uaauaaauuu cuaugauccu uuaguauucc cauccgauga auuugacgcc ucuaucucac     1440

aagucaacga aaaaauaaau caaucauuag cauucauacg aaaaucagac gaacuacuac     1500

acaacguaaa cgcaggaaaa ucaacaacca acauaaugau aaccacaaua auaauaguua     1560

uuauagugau acuauuaucc uuaauugcag ucggacuauu auuauacugu aaagcacgcu     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4973
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  4973
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caaugccauc accacaaucc      120

ugacagcagu aaccuucugc uucgcauccg gacaaaacau caccgaagaa uuuuaccagu      180

caaccugcuc cgcugucuca aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaauauca aagaaaacaa augcaacggc acugacgcca      300

agguaaaacu caucaaacag gaacucgaua aauacaagaa cgccguaaca gaacuacaac      360

uacucaugca aucaacaccg gccaccggcu ccgguuccgc cauaugcucc ggaguggccg      420

ugugcaaggu ccuccaccuu gaaggggaag uuaacaaaau caaaucagcc cuccucucca      480

cuaacaaagc cguaguaucc cuaagcaacg guguauccgu ccucaccuuc aaaguacuag      540

accuaaagaa uuauaucgac aaacaacucc uccccauacu caacaaacaa uccugcucca      600

uaagcaacau cgaaacaguc aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa      660

cccgcgaguu cucagucaac gccggaguca ccacacccgu cagcaccuac augcugacca      720

acuccgaacu ccucuccuua aucaaugaca ugcccaucac caaugaccaa aagaaacuca      780

ugucaaacaa cguccaaaua guacgccaac aauccuacuc caucaugugc aucauaaaag      840

aagaaguacu cgccuacguc guccaacucc cccucuacgg cguaaucgac acccccugcu      900

ggaaacuaca cacaagcccc cucugcacca caaacacuaa agagggcucc aacaucuguc      960

uaacccgcac cgaucgaggc ugguacugcg acaacgccgg aucugucuca uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucgagaa     1080

cccucccuuc cgaagucaac cuaugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cucgaaaacc gacguaucau ccagcgucau caccagccua ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa     1260

cuuucuccaa cggcugcgac uacgucucca acaagggagu cgauaccguc uccguaggca     1320

acacccucua cugcgucaac aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa     1380

ucauaaacuu cuacgacccu cuaguuuucc cauccgacga guucgacgcu agcaucuccc     1440

aagucaacga gaaaaucaac caaucccucg cauucauccg caaauccgac gaacuccucc     1500

acaacguaaa cgcaggcaaa ucaacuacua auauaaugau cacaaccauc auaauaguca     1560

uaaucguaau ccuccuaucc cucaucgccg ucggacuacu gcucuacugc aaagcccgcu     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  4974
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4974
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4975
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4975
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4976
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  4976
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4977
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  4977
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4978
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  4978
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4979
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  4979
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4980
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  4980
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acuaaaagcu      120

aacgccauaa ccacuauacu aacagcaguc acauucugcu ucgcaucagg ccaaaacaua      180

accgaagaau uuuaccaauc cacuuguuca gcagucucca aaggauauuu auccgcacuu      240

cguacaggau gguauacauc aguaauaaca auagaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgcaaa aguaaaacuc aucaaacaag aauuagacaa auacaagaac      360

gccguaacag aacuacaauu acuaaugcaa ucaacacccg ccacaggauc aggaucugca      420

auaugcucug gaguagcagu augcaaagua uuacaccuag aaggagaagu aaacaaaauc      480

aaaagcgcac uacuauccac aaacaaagcu guaguaucac uaucaaacgg aguaucagua      540

uuaacuuuca aaguacuuga ucuaaaaaac uacauagaca aacaacuacu acccauauua      600

aacaaacaau caugcucaau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuac uagaaaucac aagggaauuu ucaguaaaug ccgguguuac aaccccagua      720

ucaacauaca ugcuaacuaa cucagaacua cuauccuuaa uaaacgauau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag uaagacaaca aucauacuca      840

aucaugugca uuauaaaaga agaagucuua gcauacguag uacaauuacc acuauacggu      900

guaauagaua caccauguug gaaauuacac acaagcccac uaugcacaac uaacacaaaa      960

gaaggcucaa auauauguuu aacaagaaca gaccgagguu gguacugcga caaugcagga     1020

ucaguaucau ucuuuccaca agcagaaaca uguaaaguuc aauccaacag aguauucugc     1080

gacacaauga acuccagaac acuaccuuca gaaguaaacc ucuguaacgu agacauauuu     1140

aaucccaagu acgacugcaa aauaaugaca ucgaaaacag acguaagcuc cucagugaua     1200

acaucccucg gcgccaucgu auccuguuac gguaaaacua aauguaccgc cucaaacaaa     1260

aaccgcggua uuauaaaaac uuuuucuaau ggcugcgauu acguaagcaa caaaggcguc     1320

gacacaguuu ccguaggaaa cacacuauac ugcguaaaca aacaagaagg uaaaucucua     1380

uacguaaaag gagaaccaau aauaaauuuc uaugauccuu uaguauuccc auccgaugaa     1440

uuugacgccu cuaucucaca agucaacgaa aaaauaaauc aaucauuagc auucauacga     1500

aaaucagacg aacuacuaca caacguaaac gcaggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaauaguuau uauagugaua cuauuauccu uaauugcagu cggacuauua     1620

uuauacugua aagcacgcua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4981
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  4981
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aaugccauca ccacaauccu gacagcagua accuucugcu ucgcauccgg acaaaacauc      180

accgaagaau uuuaccaguc aaccugcucc gcugucucaa aaggcuaccu cucagcccuu      240

cgcaccggcu gguacaccuc ggucauaaca auagaacucu ccaauaucaa agaaaacaaa      300

ugcaacggca cugacgccaa gguaaaacuc aucaaacagg aacucgauaa auacaagaac      360

gccguaacag aacuacaacu acucaugcaa ucaacaccgg ccaccggcuc cgguuccgcc      420

auaugcuccg gaguggccgu gugcaagguc cuccaccuug aaggggaagu uaacaaaauc      480

aaaucagccc uccucuccac uaacaaagcc guaguauccc uaagcaacgg uguauccguc      540

cucaccuuca aaguacuaga ccuaaagaau uauaucgaca aacaacuccu ccccauacuc      600

aacaaacaau ccugcuccau aagcaacauc gaaacaguca ucgaguucca gcagaaaaac      660

aaccgacucc ucgaaauaac ccgcgaguuc ucagucaacg ccggagucac cacacccguc      720

agcaccuaca ugcugaccaa cuccgaacuc cucuccuuaa ucaaugacau gcccaucacc      780

aaugaccaaa agaaacucau gucaaacaac guccaaauag uacgccaaca auccuacucc      840

aucaugugca ucauaaaaga agaaguacuc gccuacgucg uccaacuccc ccucuacggc      900

guaaucgaca cccccugcug gaaacuacac acaagccccc ucugcaccac aaacacuaaa      960

gagggcucca acaucugucu aacccgcacc gaucgaggcu gguacugcga caacgccgga     1020

ucugucucau ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucgagaac ccucccuucc gaagucaacc uaugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucgaaaaccg acguaucauc cagcgucauc     1200

accagccuag gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc gagcaauaaa     1260

aaccgcggga ucaucaaaac uuucuccaac ggcugcgacu acgucuccaa caagggaguc     1320

gauaccgucu ccguaggcaa cacccucuac ugcgucaaca aacaagaagg caaaucacua     1380

uacguaaaag gcgagccaau cauaaacuuc uacgacccuc uaguuuuccc auccgacgag     1440

uucgacgcua gcaucuccca agucaacgag aaaaucaacc aaucccucgc auucauccgc     1500

aaauccgacg aacuccucca caacguaaac gcaggcaaau caacuacuaa uauaaugauc     1560

acaaccauca uaauagucau aaucguaauc cuccuauccc ucaucgccgu cggacuacug     1620

cucuacugca aagcccgcua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  4982
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4982
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4983
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4983
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4984
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  4984
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4985
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  4985
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4986
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  4986
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4987
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  4987
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4988
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  4988
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac uaaaagcuaa cgccauaacc acuauacuaa cagcagucac auucugcuuc      240

gcaucaggcc aaaacauaac cgaagaauuu uaccaaucca cuuguucagc agucuccaaa      300

ggauauuuau ccgcacuucg uacaggaugg uauacaucag uaauaacaau agaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgcaaaag uaaaacucau caaacaagaa      420

uuagacaaau acaagaacgc cguaacagaa cuacaauuac uaaugcaauc aacacccgcc      480

acaggaucag gaucugcaau augcucugga guagcaguau gcaaaguauu acaccuagaa      540

ggagaaguaa acaaaaucaa aagcgcacua cuauccacaa acaaagcugu aguaucacua      600

ucaaacggag uaucaguauu aacuuucaaa guacuugauc uaaaaaacua cauagacaaa      660

caacuacuac ccauauuaaa caaacaauca ugcucaauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuacua gaaaucacaa gggaauuuuc aguaaaugcc      780

gguguuacaa ccccaguauc aacauacaug cuaacuaacu cagaacuacu auccuuaaua      840

aacgauaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauacucaau caugugcauu auaaaagaag aagucuuagc auacguagua      960

caauuaccac uauacggugu aauagauaca ccauguugga aauuacacac aagcccacua     1020

ugcacaacua acacaaaaga aggcucaaau auauguuuaa caagaacaga ccgagguugg     1080

uacugcgaca augcaggauc aguaucauuc uuuccacaag cagaaacaug uaaaguucaa     1140

uccaacagag uauucugcga cacaaugaac uccagaacac uaccuucaga aguaaaccuc     1200

uguaacguag acauauuuaa ucccaaguac gacugcaaaa uaaugacauc gaaaacagac     1260

guaagcuccu cagugauaac aucccucggc gccaucguau ccuguuacgg uaaaacuaaa     1320

uguaccgccu caaacaaaaa ccgcgguauu auaaaaacuu uuucuaaugg cugcgauuac     1380

guaagcaaca aaggcgucga cacaguuucc guaggaaaca cacuauacug cguaaacaaa     1440

caagaaggua aaucucuaua cguaaaagga gaaccaauaa uaaauuucua ugauccuuua     1500

guauucccau ccgaugaauu ugacgccucu aucucacaag ucaacgaaaa aauaaaucaa     1560

ucauuagcau ucauacgaaa aucagacgaa cuacuacaca acguaaacgc aggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua auaguuauua uagugauacu auuauccuua     1680

auugcagucg gacuauuauu auacuguaaa gcacgcuaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4989
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  4989
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa ugccaucacc acaauccuga cagcaguaac cuucugcuuc      240

gcauccggac aaaacaucac cgaagaauuu uaccagucaa ccugcuccgc ugucucaaaa      300

ggcuaccucu cagcccuucg caccggcugg uacaccucgg ucauaacaau agaacucucc      360

aauaucaaag aaaacaaaug caacggcacu gacgccaagg uaaaacucau caaacaggaa      420

cucgauaaau acaagaacgc cguaacagaa cuacaacuac ucaugcaauc aacaccggcc      480

accggcuccg guuccgccau augcuccgga guggccgugu gcaagguccu ccaccuugaa      540

ggggaaguua acaaaaucaa aucagcccuc cucuccacua acaaagccgu aguaucccua      600

agcaacggug uauccguccu caccuucaaa guacuagacc uaaagaauua uaucgacaaa      660

caacuccucc ccauacucaa caaacaaucc ugcuccauaa gcaacaucga aacagucauc      720

gaguuccagc agaaaaacaa ccgacuccuc gaaauaaccc gcgaguucuc agucaacgcc      780

ggagucacca cacccgucag caccuacaug cugaccaacu ccgaacuccu cuccuuaauc      840

aaugacaugc ccaucaccaa ugaccaaaag aaacucaugu caaacaacgu ccaaauagua      900

cgccaacaau ccuacuccau caugugcauc auaaaagaag aaguacucgc cuacgucguc      960

caacuccccc ucuacggcgu aaucgacacc cccugcugga aacuacacac aagcccccuc     1020

ugcaccacaa acacuaaaga gggcuccaac aucugucuaa cccgcaccga ucgaggcugg     1080

uacugcgaca acgccggauc ugucucauuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucgagaaccc ucccuuccga agucaaccua     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc gaaaaccgac     1260

guaucaucca gcgucaucac cagccuaggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgcga gcaauaaaaa ccgcgggauc aucaaaacuu ucuccaacgg cugcgacuac     1380

gucuccaaca agggagucga uaccgucucc guaggcaaca cccucuacug cgucaacaaa     1440

caagaaggca aaucacuaua cguaaaaggc gagccaauca uaaacuucua cgacccucua     1500

guuuucccau ccgacgaguu cgacgcuagc aucucccaag ucaacgagaa aaucaaccaa     1560

ucccucgcau ucauccgcaa auccgacgaa cuccuccaca acguaaacgc aggcaaauca     1620

acuacuaaua uaaugaucac aaccaucaua auagucauaa ucguaauccu ccuaucccuc     1680

aucgccgucg gacuacugcu cuacugcaaa gcccgcuaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  4990
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4990
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4991
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4991
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4992
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  4992
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4993
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  4993
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4994
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  4994
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4995
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  4995
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4996
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  4996
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu aaaagcuaac gccauaacca cuauacuaac agcagucaca      180

uucugcuucg caucaggcca aaacauaacc gaagaauuuu accaauccac uuguucagca      240

gucuccaaag gauauuuauc cgcacuucgu acaggauggu auacaucagu aauaacaaua      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgcaaaagu aaaacucauc      360

aaacaagaau uagacaaaua caagaacgcc guaacagaac uacaauuacu aaugcaauca      420

acacccgcca caggaucagg aucugcaaua ugcucuggag uagcaguaug caaaguauua      480

caccuagaag gagaaguaaa caaaaucaaa agcgcacuac uauccacaaa caaagcugua      540

guaucacuau caaacggagu aucaguauua acuuucaaag uacuugaucu aaaaaacuac      600

auagacaaac aacuacuacc cauauuaaac aaacaaucau gcucaauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuacuag aaaucacaag ggaauuuuca      720

guaaaugccg guguuacaac cccaguauca acauacaugc uaacuaacuc agaacuacua      780

uccuuaauaa acgauaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguaa gacaacaauc auacucaauc augugcauua uaaaagaaga agucuuagca      900

uacguaguac aauuaccacu auacggugua auagauacac cauguuggaa auuacacaca      960

agcccacuau gcacaacuaa cacaaaagaa ggcucaaaua uauguuuaac aagaacagac     1020

cgagguuggu acugcgacaa ugcaggauca guaucauucu uuccacaagc agaaacaugu     1080

aaaguucaau ccaacagagu auucugcgac acaaugaacu ccagaacacu accuucagaa     1140

guaaaccucu guaacguaga cauauuuaau cccaaguacg acugcaaaau aaugacaucg     1200

aaaacagacg uaagcuccuc agugauaaca ucccucggcg ccaucguauc cuguuacggu     1260

aaaacuaaau guaccgccuc aaacaaaaac cgcgguauua uaaaaacuuu uucuaauggc     1320

ugcgauuacg uaagcaacaa aggcgucgac acaguuuccg uaggaaacac acuauacugc     1380

guaaacaaac aagaagguaa aucucuauac guaaaaggag aaccaauaau aaauuucuau     1440

gauccuuuag uauucccauc cgaugaauuu gacgccucua ucucacaagu caacgaaaaa     1500

auaaaucaau cauuagcauu cauacgaaaa ucagacgaac uacuacacaa cguaaacgca     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa uaguuauuau agugauacua     1620

uuauccuuaa uugcagucgg acuauuauua uacuguaaag cacgcuaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4997
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  4997
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaau gccaucacca caauccugac agcaguaacc      180

uucugcuucg cauccggaca aaacaucacc gaagaauuuu accagucaac cugcuccgcu      240

gucucaaaag gcuaccucuc agcccuucgc accggcuggu acaccucggu cauaacaaua      300

gaacucucca auaucaaaga aaacaaaugc aacggcacug acgccaaggu aaaacucauc      360

aaacaggaac ucgauaaaua caagaacgcc guaacagaac uacaacuacu caugcaauca      420

acaccggcca ccggcuccgg uuccgccaua ugcuccggag uggccgugug caagguccuc      480

caccuugaag gggaaguuaa caaaaucaaa ucagcccucc ucuccacuaa caaagccgua      540

guaucccuaa gcaacggugu auccguccuc accuucaaag uacuagaccu aaagaauuau      600

aucgacaaac aacuccuccc cauacucaac aaacaauccu gcuccauaag caacaucgaa      660

acagucaucg aguuccagca gaaaaacaac cgacuccucg aaauaacccg cgaguucuca      720

gucaacgccg gagucaccac acccgucagc accuacaugc ugaccaacuc cgaacuccuc      780

uccuuaauca augacaugcc caucaccaau gaccaaaaga aacucauguc aaacaacguc      840

caaauaguac gccaacaauc cuacuccauc augugcauca uaaaagaaga aguacucgcc      900

uacgucgucc aacucccccu cuacggcgua aucgacaccc ccugcuggaa acuacacaca      960

agcccccucu gcaccacaaa cacuaaagag ggcuccaaca ucugucuaac ccgcaccgau     1020

cgaggcuggu acugcgacaa cgccggaucu gucucauucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cgagaacccu cccuuccgaa     1140

gucaaccuau gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucg     1200

aaaaccgacg uaucauccag cgucaucacc agccuaggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgcgag caauaaaaac cgcgggauca ucaaaacuuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggagucgau accgucuccg uaggcaacac ccucuacugc     1380

gucaacaaac aagaaggcaa aucacuauac guaaaaggcg agccaaucau aaacuucuac     1440

gacccucuag uuuucccauc cgacgaguuc gacgcuagca ucucccaagu caacgagaaa     1500

aucaaccaau cccucgcauu cauccgcaaa uccgacgaac uccuccacaa cguaaacgca     1560

ggcaaaucaa cuacuaauau aaugaucaca accaucauaa uagucauaau cguaauccuc     1620

cuaucccuca ucgccgucgg acuacugcuc uacugcaaag cccgcuaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  4998
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4998
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  4999
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  4999
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  5000
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5000
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  5001
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5001
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  5002
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5002
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  5003
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5003
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  5004
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5004
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacuaaaa gcuaacgcca uaaccacuau acuaacagca      120

gucacauucu gcuucgcauc aggccaaaac auaaccgaag aauuuuacca auccacuugu      180

ucagcagucu ccaaaggaua uuuauccgca cuucguacag gaugguauac aucaguaaua      240

acaauagaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc aaaaguaaaa      300

cucaucaaac aagaauuaga caaauacaag aacgccguaa cagaacuaca auuacuaaug      360

caaucaacac ccgccacagg aucaggaucu gcaauaugcu cuggaguagc aguaugcaaa      420

guauuacacc uagaaggaga aguaaacaaa aucaaaagcg cacuacuauc cacaaacaaa      480

gcuguaguau cacuaucaaa cggaguauca guauuaacuu ucaaaguacu ugaucuaaaa      540

aacuacauag acaaacaacu acuacccaua uuaaacaaac aaucaugcuc aauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uacuagaaau cacaagggaa      660

uuuucaguaa augccggugu uacaacccca guaucaacau acaugcuaac uaacucagaa      720

cuacuauccu uaauaaacga uaugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uaguaagaca acaaucauac ucaaucaugu gcauuauaaa agaagaaguc      840

uuagcauacg uaguacaauu accacuauac gguguaauag auacaccaug uuggaaauua      900

cacacaagcc cacuaugcac aacuaacaca aaagaaggcu caaauauaug uuuaacaaga      960

acagaccgag guugguacug cgacaaugca ggaucaguau cauucuuucc acaagcagaa     1020

acauguaaag uucaauccaa cagaguauuc ugcgacacaa ugaacuccag aacacuaccu     1080

ucagaaguaa accucuguaa cguagacaua uuuaauccca aguacgacug caaaauaaug     1140

acaucgaaaa cagacguaag cuccucagug auaacauccc ucggcgccau cguauccugu     1200

uacgguaaaa cuaaauguac cgccucaaac aaaaaccgcg guauuauaaa aacuuuuucu     1260

aauggcugcg auuacguaag caacaaaggc gucgacacag uuuccguagg aaacacacua     1320

uacugcguaa acaaacaaga agguaaaucu cuauacguaa aaggagaacc aauaauaaau     1380

uucuaugauc cuuuaguauu cccauccgau gaauuugacg ccucuaucuc acaagucaac     1440

gaaaaaauaa aucaaucauu agcauucaua cgaaaaucag acgaacuacu acacaacgua     1500

aacgcaggaa aaucaacaac caacauaaug auaaccacaa uaauaauagu uauuauagug     1560

auacuauuau ccuuaauugc agucggacua uuauuauacu guaaagcacg cuaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  5005
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5005
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaaugcca ucaccacaau ccugacagca      120

guaaccuucu gcuucgcauc cggacaaaac aucaccgaag aauuuuacca gucaaccugc      180

uccgcugucu caaaaggcua ccucucagcc cuucgcaccg gcugguacac cucggucaua      240

acaauagaac ucuccaauau caaagaaaac aaaugcaacg gcacugacgc caagguaaaa      300

cucaucaaac aggaacucga uaaauacaag aacgccguaa cagaacuaca acuacucaug      360

caaucaacac cggccaccgg cuccgguucc gccauaugcu ccggaguggc cgugugcaag      420

guccuccacc uugaagggga aguuaacaaa aucaaaucag cccuccucuc cacuaacaaa      480

gccguaguau cccuaagcaa cgguguaucc guccucaccu ucaaaguacu agaccuaaag      540

aauuauaucg acaaacaacu ccuccccaua cucaacaaac aauccugcuc cauaagcaac      600

aucgaaacag ucaucgaguu ccagcagaaa aacaaccgac uccucgaaau aacccgcgag      660

uucucaguca acgccggagu caccacaccc gucagcaccu acaugcugac caacuccgaa      720

cuccucuccu uaaucaauga caugcccauc accaaugacc aaaagaaacu caugucaaac      780

aacguccaaa uaguacgcca acaauccuac uccaucaugu gcaucauaaa agaagaagua      840

cucgccuacg ucguccaacu cccccucuac ggcguaaucg acacccccug cuggaaacua      900

cacacaagcc cccucugcac cacaaacacu aaagagggcu ccaacaucug ucuaacccgc      960

accgaucgag gcugguacug cgacaacgcc ggaucugucu cauucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucgag aacccucccu     1080

uccgaaguca accuaugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accucgaaaa ccgacguauc auccagcguc aucaccagcc uaggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgcgagcaau aaaaaccgcg ggaucaucaa aacuuucucc     1260

aacggcugcg acuacgucuc caacaaggga gucgauaccg ucuccguagg caacacccuc     1320

uacugcguca acaaacaaga aggcaaauca cuauacguaa aaggcgagcc aaucauaaac     1380

uucuacgacc cucuaguuuu cccauccgac gaguucgacg cuagcaucuc ccaagucaac     1440

gagaaaauca accaaucccu cgcauucauc cgcaaauccg acgaacuccu ccacaacgua     1500

aacgcaggca aaucaacuac uaauauaaug aucacaacca ucauaauagu cauaaucgua     1560

auccuccuau cccucaucgc cgucggacua cugcucuacu gcaaagcccg cuaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  5006
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5006
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      780

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1500

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5007
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5007
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      600

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      660

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      720

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      840

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc     1080

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1140

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1200

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1260

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1380

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1440

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1500

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1740

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5008
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5008
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      780

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1500

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5009
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5009
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      600

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      660

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      720

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      780

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      840

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      900

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      960

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua     1020

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca     1080

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc     1140

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1200

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1260

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1320

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1380

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1440

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1500

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1560

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1620

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1680

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1740

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5010
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5010
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      780

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1500

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5011
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5011
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      600

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      660

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      720

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      780

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      840

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      900

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      960

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug     1020

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu     1080

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga     1140

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1200

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1260

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1320

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1380

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1440

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1500

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1560

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1620

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1680

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1740

cugaucgccg ugggccuccu gcuguauugc aaagccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5012
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5012
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuuuuaa uacuaaaagc uaacgccaua accacuauac uaacagcagu cacauucugc      300

uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau ccacuuguuc agcagucucc      360

aaaggauauu uauccgcacu ucguacagga ugguauacau caguaauaac aauagaacuc      420

uccaacauaa aagaaaauaa augcaacggc accgacgcaa aaguaaaacu caucaaacaa      480

gaauuagaca aauacaagaa cgccguaaca gaacuacaau uacuaaugca aucaacaccc      540

gccacaggau caggaucugc aauaugcucu ggaguagcag uaugcaaagu auuacaccua      600

gaaggagaag uaaacaaaau caaaagcgca cuacuaucca caaacaaagc uguaguauca      660

cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug aucuaaaaaa cuacauagac      720

aaacaacuac uacccauauu aaacaaacaa ucaugcucaa uaagcaauau agaaacagua      780

auagaauuuc aacaaaaaaa caacagacua cuagaaauca caagggaauu uucaguaaau      840

gccgguguua caaccccagu aucaacauac augcuaacua acucagaacu acuauccuua      900

auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      960

guaagacaac aaucauacuc aaucaugugc auuauaaaag aagaagucuu agcauacgua     1020

guacaauuac cacuauacgg uguaauagau acaccauguu ggaaauuaca cacaagccca     1080

cuaugcacaa cuaacacaaa agaaggcuca aauauauguu uaacaagaac agaccgaggu     1140

ugguacugcg acaaugcagg aucaguauca uucuuuccac aagcagaaac auguaaaguu     1200

caauccaaca gaguauucug cgacacaaug aacuccagaa cacuaccuuc agaaguaaac     1260

cucuguaacg uagacauauu uaaucccaag uacgacugca aaauaaugac aucgaaaaca     1320

gacguaagcu ccucagugau aacaucccuc ggcgccaucg uauccuguua cgguaaaacu     1380

aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa cuuuuucuaa uggcugcgau     1440

uacguaagca acaaaggcgu cgacacaguu uccguaggaa acacacuaua cugcguaaac     1500

aaacaagaag guaaaucucu auacguaaaa ggagaaccaa uaauaaauuu cuaugauccu     1560

uuaguauucc cauccgauga auuugacgcc ucuaucucac aagucaacga aaaaauaaau     1620

caaucauuag cauucauacg aaaaucagac gaacuacuac acaacguaaa cgcaggaaaa     1680

ucaacaacca acauaaugau aaccacaaua auaauaguua uuauagugau acuauuaucc     1740

uuaauugcag ucggacuauu auuauacugu aaagcacgcu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5013
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5013
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccucaaagc caaugccauc accacaaucc ugacagcagu aaccuucugc      300

uucgcauccg gacaaaacau caccgaagaa uuuuaccagu caaccugcuc cgcugucuca      360

aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu cggucauaac aauagaacuc      420

uccaauauca aagaaaacaa augcaacggc acugacgcca agguaaaacu caucaaacag      480

gaacucgaua aauacaagaa cgccguaaca gaacuacaac uacucaugca aucaacaccg      540

gccaccggcu ccgguuccgc cauaugcucc ggaguggccg ugugcaaggu ccuccaccuu      600

gaaggggaag uuaacaaaau caaaucagcc cuccucucca cuaacaaagc cguaguaucc      660

cuaagcaacg guguauccgu ccucaccuuc aaaguacuag accuaaagaa uuauaucgac      720

aaacaacucc uccccauacu caacaaacaa uccugcucca uaagcaacau cgaaacaguc      780

aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa cccgcgaguu cucagucaac      840

gccggaguca ccacacccgu cagcaccuac augcugacca acuccgaacu ccucuccuua      900

aucaaugaca ugcccaucac caaugaccaa aagaaacuca ugucaaacaa cguccaaaua      960

guacgccaac aauccuacuc caucaugugc aucauaaaag aagaaguacu cgccuacguc     1020

guccaacucc cccucuacgg cguaaucgac acccccugcu ggaaacuaca cacaagcccc     1080

cucugcacca caaacacuaa agagggcucc aacaucuguc uaacccgcac cgaucgaggc     1140

ugguacugcg acaacgccgg aucugucuca uucuuccccc aagccgaaac cugcaaaguc     1200

caauccaacc gcgucuucug cgacaccaug aacucgagaa cccucccuuc cgaagucaac     1260

cuaugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cucgaaaacc     1320

gacguaucau ccagcgucau caccagccua ggcgcaaucg ugagcugcua cggcaaaacc     1380

aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa cuuucuccaa cggcugcgac     1440

uacgucucca acaagggagu cgauaccguc uccguaggca acacccucua cugcgucaac     1500

aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa ucauaaacuu cuacgacccu     1560

cuaguuuucc cauccgacga guucgacgcu agcaucuccc aagucaacga gaaaaucaac     1620

caaucccucg cauucauccg caaauccgac gaacuccucc acaacguaaa cgcaggcaaa     1680

ucaacuacua auauaaugau cacaaccauc auaauaguca uaaucguaau ccuccuaucc     1740

cucaucgccg ucggacuacu gcucuacugc aaagcccgcu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5014
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5014
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5015
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5015
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5016
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5016
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5017
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5017
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca      900

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc      960

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1020

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1200

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1320

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5018
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5018
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5019
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5019
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu      900

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga      960

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1200

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguauugc aaagccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5020
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5020
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuuuuaa uacuaaaagc uaacgccaua accacuauac uaacagcagu cacauucugc      120

uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau ccacuuguuc agcagucucc      180

aaaggauauu uauccgcacu ucguacagga ugguauacau caguaauaac aauagaacuc      240

uccaacauaa aagaaaauaa augcaacggc accgacgcaa aaguaaaacu caucaaacaa      300

gaauuagaca aauacaagaa cgccguaaca gaacuacaau uacuaaugca aucaacaccc      360

gccacaggau caggaucugc aauaugcucu ggaguagcag uaugcaaagu auuacaccua      420

gaaggagaag uaaacaaaau caaaagcgca cuacuaucca caaacaaagc uguaguauca      480

cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug aucuaaaaaa cuacauagac      540

aaacaacuac uacccauauu aaacaaacaa ucaugcucaa uaagcaauau agaaacagua      600

auagaauuuc aacaaaaaaa caacagacua cuagaaauca caagggaauu uucaguaaau      660

gccgguguua caaccccagu aucaacauac augcuaacua acucagaacu acuauccuua      720

auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      780

guaagacaac aaucauacuc aaucaugugc auuauaaaag aagaagucuu agcauacgua      840

guacaauuac cacuauacgg uguaauagau acaccauguu ggaaauuaca cacaagccca      900

cuaugcacaa cuaacacaaa agaaggcuca aauauauguu uaacaagaac agaccgaggu      960

ugguacugcg acaaugcagg aucaguauca uucuuuccac aagcagaaac auguaaaguu     1020

caauccaaca gaguauucug cgacacaaug aacuccagaa cacuaccuuc agaaguaaac     1080

cucuguaacg uagacauauu uaaucccaag uacgacugca aaauaaugac aucgaaaaca     1140

gacguaagcu ccucagugau aacaucccuc ggcgccaucg uauccuguua cgguaaaacu     1200

aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa cuuuuucuaa uggcugcgau     1260

uacguaagca acaaaggcgu cgacacaguu uccguaggaa acacacuaua cugcguaaac     1320

aaacaagaag guaaaucucu auacguaaaa ggagaaccaa uaauaaauuu cuaugauccu     1380

uuaguauucc cauccgauga auuugacgcc ucuaucucac aagucaacga aaaaauaaau     1440

caaucauuag cauucauacg aaaaucagac gaacuacuac acaacguaaa cgcaggaaaa     1500

ucaacaacca acauaaugau aaccacaaua auaauaguua uuauagugau acuauuaucc     1560

uuaauugcag ucggacuauu auuauacugu aaagcacgcu aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5021
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5021
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccucaaagc caaugccauc accacaaucc ugacagcagu aaccuucugc      120

uucgcauccg gacaaaacau caccgaagaa uuuuaccagu caaccugcuc cgcugucuca      180

aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu cggucauaac aauagaacuc      240

uccaauauca aagaaaacaa augcaacggc acugacgcca agguaaaacu caucaaacag      300

gaacucgaua aauacaagaa cgccguaaca gaacuacaac uacucaugca aucaacaccg      360

gccaccggcu ccgguuccgc cauaugcucc ggaguggccg ugugcaaggu ccuccaccuu      420

gaaggggaag uuaacaaaau caaaucagcc cuccucucca cuaacaaagc cguaguaucc      480

cuaagcaacg guguauccgu ccucaccuuc aaaguacuag accuaaagaa uuauaucgac      540

aaacaacucc uccccauacu caacaaacaa uccugcucca uaagcaacau cgaaacaguc      600

aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa cccgcgaguu cucagucaac      660

gccggaguca ccacacccgu cagcaccuac augcugacca acuccgaacu ccucuccuua      720

aucaaugaca ugcccaucac caaugaccaa aagaaacuca ugucaaacaa cguccaaaua      780

guacgccaac aauccuacuc caucaugugc aucauaaaag aagaaguacu cgccuacguc      840

guccaacucc cccucuacgg cguaaucgac acccccugcu ggaaacuaca cacaagcccc      900

cucugcacca caaacacuaa agagggcucc aacaucuguc uaacccgcac cgaucgaggc      960

ugguacugcg acaacgccgg aucugucuca uucuuccccc aagccgaaac cugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucgagaa cccucccuuc cgaagucaac     1080

cuaugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cucgaaaacc     1140

gacguaucau ccagcgucau caccagccua ggcgcaaucg ugagcugcua cggcaaaacc     1200

aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa cuuucuccaa cggcugcgac     1260

uacgucucca acaagggagu cgauaccguc uccguaggca acacccucua cugcgucaac     1320

aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa ucauaaacuu cuacgacccu     1380

cuaguuuucc cauccgacga guucgacgcu agcaucuccc aagucaacga gaaaaucaac     1440

caaucccucg cauucauccg caaauccgac gaacuccucc acaacguaaa cgcaggcaaa     1500

ucaacuacua auauaaugau cacaaccauc auaauaguca uaaucguaau ccuccuaucc     1560

cucaucgccg ucggacuacu gcucuacugc aaagcccgcu aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  5022
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5022
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5023
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5023
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5024
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5024
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5025
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5025
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5026
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5026
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5027
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5027
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5028
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5028
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacuaaaagc uaacgccaua accacuauac      120

uaacagcagu cacauucugc uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau      180

ccacuuguuc agcagucucc aaaggauauu uauccgcacu ucguacagga ugguauacau      240

caguaauaac aauagaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcaa      300

aaguaaaacu caucaaacaa gaauuagaca aauacaagaa cgccguaaca gaacuacaau      360

uacuaaugca aucaacaccc gccacaggau caggaucugc aauaugcucu ggaguagcag      420

uaugcaaagu auuacaccua gaaggagaag uaaacaaaau caaaagcgca cuacuaucca      480

caaacaaagc uguaguauca cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug      540

aucuaaaaaa cuacauagac aaacaacuac uacccauauu aaacaaacaa ucaugcucaa      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua cuagaaauca      660

caagggaauu uucaguaaau gccgguguua caaccccagu aucaacauac augcuaacua      720

acucagaacu acuauccuua auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauacuc aaucaugugc auuauaaaag      840

aagaagucuu agcauacgua guacaauuac cacuauacgg uguaauagau acaccauguu      900

ggaaauuaca cacaagccca cuaugcacaa cuaacacaaa agaaggcuca aauauauguu      960

uaacaagaac agaccgaggu ugguacugcg acaaugcagg aucaguauca uucuuuccac     1020

aagcagaaac auguaaaguu caauccaaca gaguauucug cgacacaaug aacuccagaa     1080

cacuaccuuc agaaguaaac cucuguaacg uagacauauu uaaucccaag uacgacugca     1140

aaauaaugac aucgaaaaca gacguaagcu ccucagugau aacaucccuc ggcgccaucg     1200

uauccuguua cgguaaaacu aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa     1260

cuuuuucuaa uggcugcgau uacguaagca acaaaggcgu cgacacaguu uccguaggaa     1320

acacacuaua cugcguaaac aaacaagaag guaaaucucu auacguaaaa ggagaaccaa     1380

uaauaaauuu cuaugauccu uuaguauucc cauccgauga auuugacgcc ucuaucucac     1440

aagucaacga aaaaauaaau caaucauuag cauucauacg aaaaucagac gaacuacuac     1500

acaacguaaa cgcaggaaaa ucaacaacca acauaaugau aaccacaaua auaauaguua     1560

uuauagugau acuauuaucc uuaauugcag ucggacuauu auuauacugu aaagcacgcu     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5029
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5029
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caaugccauc accacaaucc      120

ugacagcagu aaccuucugc uucgcauccg gacaaaacau caccgaagaa uuuuaccagu      180

caaccugcuc cgcugucuca aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaauauca aagaaaacaa augcaacggc acugacgcca      300

agguaaaacu caucaaacag gaacucgaua aauacaagaa cgccguaaca gaacuacaac      360

uacucaugca aucaacaccg gccaccggcu ccgguuccgc cauaugcucc ggaguggccg      420

ugugcaaggu ccuccaccuu gaaggggaag uuaacaaaau caaaucagcc cuccucucca      480

cuaacaaagc cguaguaucc cuaagcaacg guguauccgu ccucaccuuc aaaguacuag      540

accuaaagaa uuauaucgac aaacaacucc uccccauacu caacaaacaa uccugcucca      600

uaagcaacau cgaaacaguc aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa      660

cccgcgaguu cucagucaac gccggaguca ccacacccgu cagcaccuac augcugacca      720

acuccgaacu ccucuccuua aucaaugaca ugcccaucac caaugaccaa aagaaacuca      780

ugucaaacaa cguccaaaua guacgccaac aauccuacuc caucaugugc aucauaaaag      840

aagaaguacu cgccuacguc guccaacucc cccucuacgg cguaaucgac acccccugcu      900

ggaaacuaca cacaagcccc cucugcacca caaacacuaa agagggcucc aacaucuguc      960

uaacccgcac cgaucgaggc ugguacugcg acaacgccgg aucugucuca uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucgagaa     1080

cccucccuuc cgaagucaac cuaugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cucgaaaacc gacguaucau ccagcgucau caccagccua ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa     1260

cuuucuccaa cggcugcgac uacgucucca acaagggagu cgauaccguc uccguaggca     1320

acacccucua cugcgucaac aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa     1380

ucauaaacuu cuacgacccu cuaguuuucc cauccgacga guucgacgcu agcaucuccc     1440

aagucaacga gaaaaucaac caaucccucg cauucauccg caaauccgac gaacuccucc     1500

acaacguaaa cgcaggcaaa ucaacuacua auauaaugau cacaaccauc auaauaguca     1560

uaaucguaau ccuccuaucc cucaucgccg ucggacuacu gcucuacugc aaagcccgcu     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5030
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5030
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5031
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5031
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5032
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5032
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5033
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5033
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5034
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5034
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5035
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5035
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5036
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5036
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacuaaaagc uaacgccaua accacuauac      120

uaacagcagu cacauucugc uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau      180

ccacuuguuc agcagucucc aaaggauauu uauccgcacu ucguacagga ugguauacau      240

caguaauaac aauagaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcaa      300

aaguaaaacu caucaaacaa gaauuagaca aauacaagaa cgccguaaca gaacuacaau      360

uacuaaugca aucaacaccc gccacaggau caggaucugc aauaugcucu ggaguagcag      420

uaugcaaagu auuacaccua gaaggagaag uaaacaaaau caaaagcgca cuacuaucca      480

caaacaaagc uguaguauca cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug      540

aucuaaaaaa cuacauagac aaacaacuac uacccauauu aaacaaacaa ucaugcucaa      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua cuagaaauca      660

caagggaauu uucaguaaau gccgguguua caaccccagu aucaacauac augcuaacua      720

acucagaacu acuauccuua auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauacuc aaucaugugc auuauaaaag      840

aagaagucuu agcauacgua guacaauuac cacuauacgg uguaauagau acaccauguu      900

ggaaauuaca cacaagccca cuaugcacaa cuaacacaaa agaaggcuca aauauauguu      960

uaacaagaac agaccgaggu ugguacugcg acaaugcagg aucaguauca uucuuuccac     1020

aagcagaaac auguaaaguu caauccaaca gaguauucug cgacacaaug aacuccagaa     1080

cacuaccuuc agaaguaaac cucuguaacg uagacauauu uaaucccaag uacgacugca     1140

aaauaaugac aucgaaaaca gacguaagcu ccucagugau aacaucccuc ggcgccaucg     1200

uauccuguua cgguaaaacu aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa     1260

cuuuuucuaa uggcugcgau uacguaagca acaaaggcgu cgacacaguu uccguaggaa     1320

acacacuaua cugcguaaac aaacaagaag guaaaucucu auacguaaaa ggagaaccaa     1380

uaauaaauuu cuaugauccu uuaguauucc cauccgauga auuugacgcc ucuaucucac     1440

aagucaacga aaaaauaaau caaucauuag cauucauacg aaaaucagac gaacuacuac     1500

acaacguaaa cgcaggaaaa ucaacaacca acauaaugau aaccacaaua auaauaguua     1560

uuauagugau acuauuaucc uuaauugcag ucggacuauu auuauacugu aaagcacgcu     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5037
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5037
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caaugccauc accacaaucc      120

ugacagcagu aaccuucugc uucgcauccg gacaaaacau caccgaagaa uuuuaccagu      180

caaccugcuc cgcugucuca aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaauauca aagaaaacaa augcaacggc acugacgcca      300

agguaaaacu caucaaacag gaacucgaua aauacaagaa cgccguaaca gaacuacaac      360

uacucaugca aucaacaccg gccaccggcu ccgguuccgc cauaugcucc ggaguggccg      420

ugugcaaggu ccuccaccuu gaaggggaag uuaacaaaau caaaucagcc cuccucucca      480

cuaacaaagc cguaguaucc cuaagcaacg guguauccgu ccucaccuuc aaaguacuag      540

accuaaagaa uuauaucgac aaacaacucc uccccauacu caacaaacaa uccugcucca      600

uaagcaacau cgaaacaguc aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa      660

cccgcgaguu cucagucaac gccggaguca ccacacccgu cagcaccuac augcugacca      720

acuccgaacu ccucuccuua aucaaugaca ugcccaucac caaugaccaa aagaaacuca      780

ugucaaacaa cguccaaaua guacgccaac aauccuacuc caucaugugc aucauaaaag      840

aagaaguacu cgccuacguc guccaacucc cccucuacgg cguaaucgac acccccugcu      900

ggaaacuaca cacaagcccc cucugcacca caaacacuaa agagggcucc aacaucuguc      960

uaacccgcac cgaucgaggc ugguacugcg acaacgccgg aucugucuca uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucgagaa     1080

cccucccuuc cgaagucaac cuaugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cucgaaaacc gacguaucau ccagcgucau caccagccua ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa     1260

cuuucuccaa cggcugcgac uacgucucca acaagggagu cgauaccguc uccguaggca     1320

acacccucua cugcgucaac aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa     1380

ucauaaacuu cuacgacccu cuaguuuucc cauccgacga guucgacgcu agcaucuccc     1440

aagucaacga gaaaaucaac caaucccucg cauucauccg caaauccgac gaacuccucc     1500

acaacguaaa cgcaggcaaa ucaacuacua auauaaugau cacaaccauc auaauaguca     1560

uaaucguaau ccuccuaucc cucaucgccg ucggacuacu gcucuacugc aaagcccgcu     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  5038
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5038
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5039
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5039
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5040
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5040
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5041
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5041
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5042
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5042
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5043
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5043
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5044
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5044
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu aaaagcuaac gccauaacca cuauacuaac agcagucaca      180

uucugcuucg caucaggcca aaacauaacc gaagaauuuu accaauccac uuguucagca      240

gucuccaaag gauauuuauc cgcacuucgu acaggauggu auacaucagu aauaacaaua      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgcaaaagu aaaacucauc      360

aaacaagaau uagacaaaua caagaacgcc guaacagaac uacaauuacu aaugcaauca      420

acacccgcca caggaucagg aucugcaaua ugcucuggag uagcaguaug caaaguauua      480

caccuagaag gagaaguaaa caaaaucaaa agcgcacuac uauccacaaa caaagcugua      540

guaucacuau caaacggagu aucaguauua acuuucaaag uacuugaucu aaaaaacuac      600

auagacaaac aacuacuacc cauauuaaac aaacaaucau gcucaauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuacuag aaaucacaag ggaauuuuca      720

guaaaugccg guguuacaac cccaguauca acauacaugc uaacuaacuc agaacuacua      780

uccuuaauaa acgauaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguaa gacaacaauc auacucaauc augugcauua uaaaagaaga agucuuagca      900

uacguaguac aauuaccacu auacggugua auagauacac cauguuggaa auuacacaca      960

agcccacuau gcacaacuaa cacaaaagaa ggcucaaaua uauguuuaac aagaacagac     1020

cgagguuggu acugcgacaa ugcaggauca guaucauucu uuccacaagc agaaacaugu     1080

aaaguucaau ccaacagagu auucugcgac acaaugaacu ccagaacacu accuucagaa     1140

guaaaccucu guaacguaga cauauuuaau cccaaguacg acugcaaaau aaugacaucg     1200

aaaacagacg uaagcuccuc agugauaaca ucccucggcg ccaucguauc cuguuacggu     1260

aaaacuaaau guaccgccuc aaacaaaaac cgcgguauua uaaaaacuuu uucuaauggc     1320

ugcgauuacg uaagcaacaa aggcgucgac acaguuuccg uaggaaacac acuauacugc     1380

guaaacaaac aagaagguaa aucucuauac guaaaaggag aaccaauaau aaauuucuau     1440

gauccuuuag uauucccauc cgaugaauuu gacgccucua ucucacaagu caacgaaaaa     1500

auaaaucaau cauuagcauu cauacgaaaa ucagacgaac uacuacacaa cguaaacgca     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa uaguuauuau agugauacua     1620

uuauccuuaa uugcagucgg acuauuauua uacuguaaag cacgcuaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5045
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5045
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaau gccaucacca caauccugac agcaguaacc      180

uucugcuucg cauccggaca aaacaucacc gaagaauuuu accagucaac cugcuccgcu      240

gucucaaaag gcuaccucuc agcccuucgc accggcuggu acaccucggu cauaacaaua      300

gaacucucca auaucaaaga aaacaaaugc aacggcacug acgccaaggu aaaacucauc      360

aaacaggaac ucgauaaaua caagaacgcc guaacagaac uacaacuacu caugcaauca      420

acaccggcca ccggcuccgg uuccgccaua ugcuccggag uggccgugug caagguccuc      480

caccuugaag gggaaguuaa caaaaucaaa ucagcccucc ucuccacuaa caaagccgua      540

guaucccuaa gcaacggugu auccguccuc accuucaaag uacuagaccu aaagaauuau      600

aucgacaaac aacuccuccc cauacucaac aaacaauccu gcuccauaag caacaucgaa      660

acagucaucg aguuccagca gaaaaacaac cgacuccucg aaauaacccg cgaguucuca      720

gucaacgccg gagucaccac acccgucagc accuacaugc ugaccaacuc cgaacuccuc      780

uccuuaauca augacaugcc caucaccaau gaccaaaaga aacucauguc aaacaacguc      840

caaauaguac gccaacaauc cuacuccauc augugcauca uaaaagaaga aguacucgcc      900

uacgucgucc aacucccccu cuacggcgua aucgacaccc ccugcuggaa acuacacaca      960

agcccccucu gcaccacaaa cacuaaagag ggcuccaaca ucugucuaac ccgcaccgau     1020

cgaggcuggu acugcgacaa cgccggaucu gucucauucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cgagaacccu cccuuccgaa     1140

gucaaccuau gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucg     1200

aaaaccgacg uaucauccag cgucaucacc agccuaggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgcgag caauaaaaac cgcgggauca ucaaaacuuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggagucgau accgucuccg uaggcaacac ccucuacugc     1380

gucaacaaac aagaaggcaa aucacuauac guaaaaggcg agccaaucau aaacuucuac     1440

gacccucuag uuuucccauc cgacgaguuc gacgcuagca ucucccaagu caacgagaaa     1500

aucaaccaau cccucgcauu cauccgcaaa uccgacgaac uccuccacaa cguaaacgca     1560

ggcaaaucaa cuacuaauau aaugaucaca accaucauaa uagucauaau cguaauccuc     1620

cuaucccuca ucgccgucgg acuacugcuc uacugcaaag cccgcuaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  5046
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5046
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5047
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5047
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5048
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5048
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5049
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5049
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5050
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5050
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5051
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5051
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5052
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5052
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acuaaaagcu      120

aacgccauaa ccacuauacu aacagcaguc acauucugcu ucgcaucagg ccaaaacaua      180

accgaagaau uuuaccaauc cacuuguuca gcagucucca aaggauauuu auccgcacuu      240

cguacaggau gguauacauc aguaauaaca auagaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgcaaa aguaaaacuc aucaaacaag aauuagacaa auacaagaac      360

gccguaacag aacuacaauu acuaaugcaa ucaacacccg ccacaggauc aggaucugca      420

auaugcucug gaguagcagu augcaaagua uuacaccuag aaggagaagu aaacaaaauc      480

aaaagcgcac uacuauccac aaacaaagcu guaguaucac uaucaaacgg aguaucagua      540

uuaacuuuca aaguacuuga ucuaaaaaac uacauagaca aacaacuacu acccauauua      600

aacaaacaau caugcucaau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuac uagaaaucac aagggaauuu ucaguaaaug ccgguguuac aaccccagua      720

ucaacauaca ugcuaacuaa cucagaacua cuauccuuaa uaaacgauau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag uaagacaaca aucauacuca      840

aucaugugca uuauaaaaga agaagucuua gcauacguag uacaauuacc acuauacggu      900

guaauagaua caccauguug gaaauuacac acaagcccac uaugcacaac uaacacaaaa      960

gaaggcucaa auauauguuu aacaagaaca gaccgagguu gguacugcga caaugcagga     1020

ucaguaucau ucuuuccaca agcagaaaca uguaaaguuc aauccaacag aguauucugc     1080

gacacaauga acuccagaac acuaccuuca gaaguaaacc ucuguaacgu agacauauuu     1140

aaucccaagu acgacugcaa aauaaugaca ucgaaaacag acguaagcuc cucagugaua     1200

acaucccucg gcgccaucgu auccuguuac gguaaaacua aauguaccgc cucaaacaaa     1260

aaccgcggua uuauaaaaac uuuuucuaau ggcugcgauu acguaagcaa caaaggcguc     1320

gacacaguuu ccguaggaaa cacacuauac ugcguaaaca aacaagaagg uaaaucucua     1380

uacguaaaag gagaaccaau aauaaauuuc uaugauccuu uaguauuccc auccgaugaa     1440

uuugacgccu cuaucucaca agucaacgaa aaaauaaauc aaucauuagc auucauacga     1500

aaaucagacg aacuacuaca caacguaaac gcaggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaauaguuau uauagugaua cuauuauccu uaauugcagu cggacuauua     1620

uuauacugua aagcacgcua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5053
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5053
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aaugccauca ccacaauccu gacagcagua accuucugcu ucgcauccgg acaaaacauc      180

accgaagaau uuuaccaguc aaccugcucc gcugucucaa aaggcuaccu cucagcccuu      240

cgcaccggcu gguacaccuc ggucauaaca auagaacucu ccaauaucaa agaaaacaaa      300

ugcaacggca cugacgccaa gguaaaacuc aucaaacagg aacucgauaa auacaagaac      360

gccguaacag aacuacaacu acucaugcaa ucaacaccgg ccaccggcuc cgguuccgcc      420

auaugcuccg gaguggccgu gugcaagguc cuccaccuug aaggggaagu uaacaaaauc      480

aaaucagccc uccucuccac uaacaaagcc guaguauccc uaagcaacgg uguauccguc      540

cucaccuuca aaguacuaga ccuaaagaau uauaucgaca aacaacuccu ccccauacuc      600

aacaaacaau ccugcuccau aagcaacauc gaaacaguca ucgaguucca gcagaaaaac      660

aaccgacucc ucgaaauaac ccgcgaguuc ucagucaacg ccggagucac cacacccguc      720

agcaccuaca ugcugaccaa cuccgaacuc cucuccuuaa ucaaugacau gcccaucacc      780

aaugaccaaa agaaacucau gucaaacaac guccaaauag uacgccaaca auccuacucc      840

aucaugugca ucauaaaaga agaaguacuc gccuacgucg uccaacuccc ccucuacggc      900

guaaucgaca cccccugcug gaaacuacac acaagccccc ucugcaccac aaacacuaaa      960

gagggcucca acaucugucu aacccgcacc gaucgaggcu gguacugcga caacgccgga     1020

ucugucucau ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucgagaac ccucccuucc gaagucaacc uaugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucgaaaaccg acguaucauc cagcgucauc     1200

accagccuag gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc gagcaauaaa     1260

aaccgcggga ucaucaaaac uuucuccaac ggcugcgacu acgucuccaa caagggaguc     1320

gauaccgucu ccguaggcaa cacccucuac ugcgucaaca aacaagaagg caaaucacua     1380

uacguaaaag gcgagccaau cauaaacuuc uacgacccuc uaguuuuccc auccgacgag     1440

uucgacgcua gcaucuccca agucaacgag aaaaucaacc aaucccucgc auucauccgc     1500

aaauccgacg aacuccucca caacguaaac gcaggcaaau caacuacuaa uauaaugauc     1560

acaaccauca uaauagucau aaucguaauc cuccuauccc ucaucgccgu cggacuacug     1620

cucuacugca aagcccgcua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  5054
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5054
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5055
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5055
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5056
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5056
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5057
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5057
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5058
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5058
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5059
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5059
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5060
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5060
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu aaaagcuaac gccauaacca cuauacuaac agcagucaca      180

uucugcuucg caucaggcca aaacauaacc gaagaauuuu accaauccac uuguucagca      240

gucuccaaag gauauuuauc cgcacuucgu acaggauggu auacaucagu aauaacaaua      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgcaaaagu aaaacucauc      360

aaacaagaau uagacaaaua caagaacgcc guaacagaac uacaauuacu aaugcaauca      420

acacccgcca caggaucagg aucugcaaua ugcucuggag uagcaguaug caaaguauua      480

caccuagaag gagaaguaaa caaaaucaaa agcgcacuac uauccacaaa caaagcugua      540

guaucacuau caaacggagu aucaguauua acuuucaaag uacuugaucu aaaaaacuac      600

auagacaaac aacuacuacc cauauuaaac aaacaaucau gcucaauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuacuag aaaucacaag ggaauuuuca      720

guaaaugccg guguuacaac cccaguauca acauacaugc uaacuaacuc agaacuacua      780

uccuuaauaa acgauaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguaa gacaacaauc auacucaauc augugcauua uaaaagaaga agucuuagca      900

uacguaguac aauuaccacu auacggugua auagauacac cauguuggaa auuacacaca      960

agcccacuau gcacaacuaa cacaaaagaa ggcucaaaua uauguuuaac aagaacagac     1020

cgagguuggu acugcgacaa ugcaggauca guaucauucu uuccacaagc agaaacaugu     1080

aaaguucaau ccaacagagu auucugcgac acaaugaacu ccagaacacu accuucagaa     1140

guaaaccucu guaacguaga cauauuuaau cccaaguacg acugcaaaau aaugacaucg     1200

aaaacagacg uaagcuccuc agugauaaca ucccucggcg ccaucguauc cuguuacggu     1260

aaaacuaaau guaccgccuc aaacaaaaac cgcgguauua uaaaaacuuu uucuaauggc     1320

ugcgauuacg uaagcaacaa aggcgucgac acaguuuccg uaggaaacac acuauacugc     1380

guaaacaaac aagaagguaa aucucuauac guaaaaggag aaccaauaau aaauuucuau     1440

gauccuuuag uauucccauc cgaugaauuu gacgccucua ucucacaagu caacgaaaaa     1500

auaaaucaau cauuagcauu cauacgaaaa ucagacgaac uacuacacaa cguaaacgca     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa uaguuauuau agugauacua     1620

uuauccuuaa uugcagucgg acuauuauua uacuguaaag cacgcuaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5061
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5061
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaau gccaucacca caauccugac agcaguaacc      180

uucugcuucg cauccggaca aaacaucacc gaagaauuuu accagucaac cugcuccgcu      240

gucucaaaag gcuaccucuc agcccuucgc accggcuggu acaccucggu cauaacaaua      300

gaacucucca auaucaaaga aaacaaaugc aacggcacug acgccaaggu aaaacucauc      360

aaacaggaac ucgauaaaua caagaacgcc guaacagaac uacaacuacu caugcaauca      420

acaccggcca ccggcuccgg uuccgccaua ugcuccggag uggccgugug caagguccuc      480

caccuugaag gggaaguuaa caaaaucaaa ucagcccucc ucuccacuaa caaagccgua      540

guaucccuaa gcaacggugu auccguccuc accuucaaag uacuagaccu aaagaauuau      600

aucgacaaac aacuccuccc cauacucaac aaacaauccu gcuccauaag caacaucgaa      660

acagucaucg aguuccagca gaaaaacaac cgacuccucg aaauaacccg cgaguucuca      720

gucaacgccg gagucaccac acccgucagc accuacaugc ugaccaacuc cgaacuccuc      780

uccuuaauca augacaugcc caucaccaau gaccaaaaga aacucauguc aaacaacguc      840

caaauaguac gccaacaauc cuacuccauc augugcauca uaaaagaaga aguacucgcc      900

uacgucgucc aacucccccu cuacggcgua aucgacaccc ccugcuggaa acuacacaca      960

agcccccucu gcaccacaaa cacuaaagag ggcuccaaca ucugucuaac ccgcaccgau     1020

cgaggcuggu acugcgacaa cgccggaucu gucucauucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cgagaacccu cccuuccgaa     1140

gucaaccuau gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucg     1200

aaaaccgacg uaucauccag cgucaucacc agccuaggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgcgag caauaaaaac cgcgggauca ucaaaacuuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggagucgau accgucuccg uaggcaacac ccucuacugc     1380

gucaacaaac aagaaggcaa aucacuauac guaaaaggcg agccaaucau aaacuucuac     1440

gacccucuag uuuucccauc cgacgaguuc gacgcuagca ucucccaagu caacgagaaa     1500

aucaaccaau cccucgcauu cauccgcaaa uccgacgaac uccuccacaa cguaaacgca     1560

ggcaaaucaa cuacuaauau aaugaucaca accaucauaa uagucauaau cguaauccuc     1620

cuaucccuca ucgccgucgg acuacugcuc uacugcaaag cccgcuaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  5062
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5062
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5063
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5063
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5064
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5064
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5065
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5065
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5066
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5066
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5067
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5067
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5068
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5068
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acuaaaagcu      120

aacgccauaa ccacuauacu aacagcaguc acauucugcu ucgcaucagg ccaaaacaua      180

accgaagaau uuuaccaauc cacuuguuca gcagucucca aaggauauuu auccgcacuu      240

cguacaggau gguauacauc aguaauaaca auagaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgcaaa aguaaaacuc aucaaacaag aauuagacaa auacaagaac      360

gccguaacag aacuacaauu acuaaugcaa ucaacacccg ccacaggauc aggaucugca      420

auaugcucug gaguagcagu augcaaagua uuacaccuag aaggagaagu aaacaaaauc      480

aaaagcgcac uacuauccac aaacaaagcu guaguaucac uaucaaacgg aguaucagua      540

uuaacuuuca aaguacuuga ucuaaaaaac uacauagaca aacaacuacu acccauauua      600

aacaaacaau caugcucaau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuac uagaaaucac aagggaauuu ucaguaaaug ccgguguuac aaccccagua      720

ucaacauaca ugcuaacuaa cucagaacua cuauccuuaa uaaacgauau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag uaagacaaca aucauacuca      840

aucaugugca uuauaaaaga agaagucuua gcauacguag uacaauuacc acuauacggu      900

guaauagaua caccauguug gaaauuacac acaagcccac uaugcacaac uaacacaaaa      960

gaaggcucaa auauauguuu aacaagaaca gaccgagguu gguacugcga caaugcagga     1020

ucaguaucau ucuuuccaca agcagaaaca uguaaaguuc aauccaacag aguauucugc     1080

gacacaauga acuccagaac acuaccuuca gaaguaaacc ucuguaacgu agacauauuu     1140

aaucccaagu acgacugcaa aauaaugaca ucgaaaacag acguaagcuc cucagugaua     1200

acaucccucg gcgccaucgu auccuguuac gguaaaacua aauguaccgc cucaaacaaa     1260

aaccgcggua uuauaaaaac uuuuucuaau ggcugcgauu acguaagcaa caaaggcguc     1320

gacacaguuu ccguaggaaa cacacuauac ugcguaaaca aacaagaagg uaaaucucua     1380

uacguaaaag gagaaccaau aauaaauuuc uaugauccuu uaguauuccc auccgaugaa     1440

uuugacgccu cuaucucaca agucaacgaa aaaauaaauc aaucauuagc auucauacga     1500

aaaucagacg aacuacuaca caacguaaac gcaggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaauaguuau uauagugaua cuauuauccu uaauugcagu cggacuauua     1620

uuauacugua aagcacgcua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5069
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5069
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aaugccauca ccacaauccu gacagcagua accuucugcu ucgcauccgg acaaaacauc      180

accgaagaau uuuaccaguc aaccugcucc gcugucucaa aaggcuaccu cucagcccuu      240

cgcaccggcu gguacaccuc ggucauaaca auagaacucu ccaauaucaa agaaaacaaa      300

ugcaacggca cugacgccaa gguaaaacuc aucaaacagg aacucgauaa auacaagaac      360

gccguaacag aacuacaacu acucaugcaa ucaacaccgg ccaccggcuc cgguuccgcc      420

auaugcuccg gaguggccgu gugcaagguc cuccaccuug aaggggaagu uaacaaaauc      480

aaaucagccc uccucuccac uaacaaagcc guaguauccc uaagcaacgg uguauccguc      540

cucaccuuca aaguacuaga ccuaaagaau uauaucgaca aacaacuccu ccccauacuc      600

aacaaacaau ccugcuccau aagcaacauc gaaacaguca ucgaguucca gcagaaaaac      660

aaccgacucc ucgaaauaac ccgcgaguuc ucagucaacg ccggagucac cacacccguc      720

agcaccuaca ugcugaccaa cuccgaacuc cucuccuuaa ucaaugacau gcccaucacc      780

aaugaccaaa agaaacucau gucaaacaac guccaaauag uacgccaaca auccuacucc      840

aucaugugca ucauaaaaga agaaguacuc gccuacgucg uccaacuccc ccucuacggc      900

guaaucgaca cccccugcug gaaacuacac acaagccccc ucugcaccac aaacacuaaa      960

gagggcucca acaucugucu aacccgcacc gaucgaggcu gguacugcga caacgccgga     1020

ucugucucau ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucgagaac ccucccuucc gaagucaacc uaugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucgaaaaccg acguaucauc cagcgucauc     1200

accagccuag gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc gagcaauaaa     1260

aaccgcggga ucaucaaaac uuucuccaac ggcugcgacu acgucuccaa caagggaguc     1320

gauaccgucu ccguaggcaa cacccucuac ugcgucaaca aacaagaagg caaaucacua     1380

uacguaaaag gcgagccaau cauaaacuuc uacgacccuc uaguuuuccc auccgacgag     1440

uucgacgcua gcaucuccca agucaacgag aaaaucaacc aaucccucgc auucauccgc     1500

aaauccgacg aacuccucca caacguaaac gcaggcaaau caacuacuaa uauaaugauc     1560

acaaccauca uaauagucau aaucguaauc cuccuauccc ucaucgccgu cggacuacug     1620

cucuacugca aagcccgcua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  5070
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5070
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5071
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5071
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5072
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5072
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5073
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5073
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5074
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5074
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5075
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5075
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5076
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5076
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acuaaaagcu      120

aacgccauaa ccacuauacu aacagcaguc acauucugcu ucgcaucagg ccaaaacaua      180

accgaagaau uuuaccaauc cacuuguuca gcagucucca aaggauauuu auccgcacuu      240

cguacaggau gguauacauc aguaauaaca auagaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgcaaa aguaaaacuc aucaaacaag aauuagacaa auacaagaac      360

gccguaacag aacuacaauu acuaaugcaa ucaacacccg ccacaggauc aggaucugca      420

auaugcucug gaguagcagu augcaaagua uuacaccuag aaggagaagu aaacaaaauc      480

aaaagcgcac uacuauccac aaacaaagcu guaguaucac uaucaaacgg aguaucagua      540

uuaacuuuca aaguacuuga ucuaaaaaac uacauagaca aacaacuacu acccauauua      600

aacaaacaau caugcucaau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuac uagaaaucac aagggaauuu ucaguaaaug ccgguguuac aaccccagua      720

ucaacauaca ugcuaacuaa cucagaacua cuauccuuaa uaaacgauau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag uaagacaaca aucauacuca      840

aucaugugca uuauaaaaga agaagucuua gcauacguag uacaauuacc acuauacggu      900

guaauagaua caccauguug gaaauuacac acaagcccac uaugcacaac uaacacaaaa      960

gaaggcucaa auauauguuu aacaagaaca gaccgagguu gguacugcga caaugcagga     1020

ucaguaucau ucuuuccaca agcagaaaca uguaaaguuc aauccaacag aguauucugc     1080

gacacaauga acuccagaac acuaccuuca gaaguaaacc ucuguaacgu agacauauuu     1140

aaucccaagu acgacugcaa aauaaugaca ucgaaaacag acguaagcuc cucagugaua     1200

acaucccucg gcgccaucgu auccuguuac gguaaaacua aauguaccgc cucaaacaaa     1260

aaccgcggua uuauaaaaac uuuuucuaau ggcugcgauu acguaagcaa caaaggcguc     1320

gacacaguuu ccguaggaaa cacacuauac ugcguaaaca aacaagaagg uaaaucucua     1380

uacguaaaag gagaaccaau aauaaauuuc uaugauccuu uaguauuccc auccgaugaa     1440

uuugacgccu cuaucucaca agucaacgaa aaaauaaauc aaucauuagc auucauacga     1500

aaaucagacg aacuacuaca caacguaaac gcaggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaauaguuau uauagugaua cuauuauccu uaauugcagu cggacuauua     1620

uuauacugua aagcacgcua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5077
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5077
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aaugccauca ccacaauccu gacagcagua accuucugcu ucgcauccgg acaaaacauc      180

accgaagaau uuuaccaguc aaccugcucc gcugucucaa aaggcuaccu cucagcccuu      240

cgcaccggcu gguacaccuc ggucauaaca auagaacucu ccaauaucaa agaaaacaaa      300

ugcaacggca cugacgccaa gguaaaacuc aucaaacagg aacucgauaa auacaagaac      360

gccguaacag aacuacaacu acucaugcaa ucaacaccgg ccaccggcuc cgguuccgcc      420

auaugcuccg gaguggccgu gugcaagguc cuccaccuug aaggggaagu uaacaaaauc      480

aaaucagccc uccucuccac uaacaaagcc guaguauccc uaagcaacgg uguauccguc      540

cucaccuuca aaguacuaga ccuaaagaau uauaucgaca aacaacuccu ccccauacuc      600

aacaaacaau ccugcuccau aagcaacauc gaaacaguca ucgaguucca gcagaaaaac      660

aaccgacucc ucgaaauaac ccgcgaguuc ucagucaacg ccggagucac cacacccguc      720

agcaccuaca ugcugaccaa cuccgaacuc cucuccuuaa ucaaugacau gcccaucacc      780

aaugaccaaa agaaacucau gucaaacaac guccaaauag uacgccaaca auccuacucc      840

aucaugugca ucauaaaaga agaaguacuc gccuacgucg uccaacuccc ccucuacggc      900

guaaucgaca cccccugcug gaaacuacac acaagccccc ucugcaccac aaacacuaaa      960

gagggcucca acaucugucu aacccgcacc gaucgaggcu gguacugcga caacgccgga     1020

ucugucucau ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucgagaac ccucccuucc gaagucaacc uaugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucgaaaaccg acguaucauc cagcgucauc     1200

accagccuag gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc gagcaauaaa     1260

aaccgcggga ucaucaaaac uuucuccaac ggcugcgacu acgucuccaa caagggaguc     1320

gauaccgucu ccguaggcaa cacccucuac ugcgucaaca aacaagaagg caaaucacua     1380

uacguaaaag gcgagccaau cauaaacuuc uacgacccuc uaguuuuccc auccgacgag     1440

uucgacgcua gcaucuccca agucaacgag aaaaucaacc aaucccucgc auucauccgc     1500

aaauccgacg aacuccucca caacguaaac gcaggcaaau caacuacuaa uauaaugauc     1560

acaaccauca uaauagucau aaucguaauc cuccuauccc ucaucgccgu cggacuacug     1620

cucuacugca aagcccgcua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  5078
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5078
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5079
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5079
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5080
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5080
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5081
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5081
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5082
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5082
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5083
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5083
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5084
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5084
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacuaaa agcuaacgcc      120

auaaccacua uacuaacagc agucacauuc ugcuucgcau caggccaaaa cauaaccgaa      180

gaauuuuacc aauccacuug uucagcaguc uccaaaggau auuuauccgc acuucguaca      240

ggaugguaua caucaguaau aacaauagaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg caaaaguaaa acucaucaaa caagaauuag acaaauacaa gaacgccgua      360

acagaacuac aauuacuaau gcaaucaaca cccgccacag gaucaggauc ugcaauaugc      420

ucuggaguag caguaugcaa aguauuacac cuagaaggag aaguaaacaa aaucaaaagc      480

gcacuacuau ccacaaacaa agcuguagua ucacuaucaa acggaguauc aguauuaacu      540

uucaaaguac uugaucuaaa aaacuacaua gacaaacaac uacuacccau auuaaacaaa      600

caaucaugcu caauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuacuagaaa ucacaaggga auuuucagua aaugccggug uuacaacccc aguaucaaca      720

uacaugcuaa cuaacucaga acuacuaucc uuaauaaacg auaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auaguaagac aacaaucaua cucaaucaug      840

ugcauuauaa aagaagaagu cuuagcauac guaguacaau uaccacuaua cgguguaaua      900

gauacaccau guuggaaauu acacacaagc ccacuaugca caacuaacac aaaagaaggc      960

ucaaauauau guuuaacaag aacagaccga gguugguacu gcgacaaugc aggaucagua     1020

ucauucuuuc cacaagcaga aacauguaaa guucaaucca acagaguauu cugcgacaca     1080

augaacucca gaacacuacc uucagaagua aaccucugua acguagacau auuuaauccc     1140

aaguacgacu gcaaaauaau gacaucgaaa acagacguaa gcuccucagu gauaacaucc     1200

cucggcgcca ucguauccug uuacgguaaa acuaaaugua ccgccucaaa caaaaaccgc     1260

gguauuauaa aaacuuuuuc uaauggcugc gauuacguaa gcaacaaagg cgucgacaca     1320

guuuccguag gaaacacacu auacugcgua aacaaacaag aagguaaauc ucuauacgua     1380

aaaggagaac caauaauaaa uuucuaugau ccuuuaguau ucccauccga ugaauuugac     1440

gccucuaucu cacaagucaa cgaaaaaaua aaucaaucau uagcauucau acgaaaauca     1500

gacgaacuac uacacaacgu aaacgcagga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaauag uuauuauagu gauacuauua uccuuaauug cagucggacu auuauuauac     1620

uguaaagcac gcuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5085
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5085
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaaugcc      120

aucaccacaa uccugacagc aguaaccuuc ugcuucgcau ccggacaaaa caucaccgaa      180

gaauuuuacc agucaaccug cuccgcuguc ucaaaaggcu accucucagc ccuucgcacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaua ucaaagaaaa caaaugcaac      300

ggcacugacg ccaagguaaa acucaucaaa caggaacucg auaaauacaa gaacgccgua      360

acagaacuac aacuacucau gcaaucaaca ccggccaccg gcuccgguuc cgccauaugc      420

uccggagugg ccgugugcaa gguccuccac cuugaagggg aaguuaacaa aaucaaauca      480

gcccuccucu ccacuaacaa agccguagua ucccuaagca acgguguauc cguccucacc      540

uucaaaguac uagaccuaaa gaauuauauc gacaaacaac uccuccccau acucaacaaa      600

caauccugcu ccauaagcaa caucgaaaca gucaucgagu uccagcagaa aaacaaccga      660

cuccucgaaa uaacccgcga guucucaguc aacgccggag ucaccacacc cgucagcacc      720

uacaugcuga ccaacuccga acuccucucc uuaaucaaug acaugcccau caccaaugac      780

caaaagaaac ucaugucaaa caacguccaa auaguacgcc aacaauccua cuccaucaug      840

ugcaucauaa aagaagaagu acucgccuac gucguccaac ucccccucua cggcguaauc      900

gacacccccu gcuggaaacu acacacaagc ccccucugca ccacaaacac uaaagagggc      960

uccaacaucu gucuaacccg caccgaucga ggcugguacu gcgacaacgc cggaucuguc     1020

ucauucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucga gaacccuccc uuccgaaguc aaccuaugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccucgaaa accgacguau cauccagcgu caucaccagc     1200

cuaggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgcgagcaa uaaaaaccgc     1260

gggaucauca aaacuuucuc caacggcugc gacuacgucu ccaacaaggg agucgauacc     1320

gucuccguag gcaacacccu cuacugcguc aacaaacaag aaggcaaauc acuauacgua     1380

aaaggcgagc caaucauaaa cuucuacgac ccucuaguuu ucccauccga cgaguucgac     1440

gcuagcaucu cccaagucaa cgagaaaauc aaccaauccc ucgcauucau ccgcaaaucc     1500

gacgaacucc uccacaacgu aaacgcaggc aaaucaacua cuaauauaau gaucacaacc     1560

aucauaauag ucauaaucgu aauccuccua ucccucaucg ccgucggacu acugcucuac     1620

ugcaaagccc gcuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  5086
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5086
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5087
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5087
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5088
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5088
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5089
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5089
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5090
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5090
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5091
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5091
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5092
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5092
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacuaaaa      120

gcuaacgcca uaaccacuau acuaacagca gucacauucu gcuucgcauc aggccaaaac      180

auaaccgaag aauuuuacca auccacuugu ucagcagucu ccaaaggaua uuuauccgca      240

cuucguacag gaugguauac aucaguaaua acaauagaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc aaaaguaaaa cucaucaaac aagaauuaga caaauacaag      360

aacgccguaa cagaacuaca auuacuaaug caaucaacac ccgccacagg aucaggaucu      420

gcaauaugcu cuggaguagc aguaugcaaa guauuacacc uagaaggaga aguaaacaaa      480

aucaaaagcg cacuacuauc cacaaacaaa gcuguaguau cacuaucaaa cggaguauca      540

guauuaacuu ucaaaguacu ugaucuaaaa aacuacauag acaaacaacu acuacccaua      600

uuaaacaaac aaucaugcuc aauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uacuagaaau cacaagggaa uuuucaguaa augccggugu uacaacccca      720

guaucaacau acaugcuaac uaacucagaa cuacuauccu uaauaaacga uaugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauuauaaa agaagaaguc uuagcauacg uaguacaauu accacuauac      900

gguguaauag auacaccaug uuggaaauua cacacaagcc cacuaugcac aacuaacaca      960

aaagaaggcu caaauauaug uuuaacaaga acagaccgag guugguacug cgacaaugca     1020

ggaucaguau cauucuuucc acaagcagaa acauguaaag uucaauccaa cagaguauuc     1080

ugcgacacaa ugaacuccag aacacuaccu ucagaaguaa accucuguaa cguagacaua     1140

uuuaauccca aguacgacug caaaauaaug acaucgaaaa cagacguaag cuccucagug     1200

auaacauccc ucggcgccau cguauccugu uacgguaaaa cuaaauguac cgccucaaac     1260

aaaaaccgcg guauuauaaa aacuuuuucu aauggcugcg auuacguaag caacaaaggc     1320

gucgacacag uuuccguagg aaacacacua uacugcguaa acaaacaaga agguaaaucu     1380

cuauacguaa aaggagaacc aauaauaaau uucuaugauc cuuuaguauu cccauccgau     1440

gaauuugacg ccucuaucuc acaagucaac gaaaaaauaa aucaaucauu agcauucaua     1500

cgaaaaucag acgaacuacu acacaacgua aacgcaggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaauagu uauuauagug auacuauuau ccuuaauugc agucggacua     1620

uuauuauacu guaaagcacg cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5093
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5093
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaaugcca ucaccacaau ccugacagca guaaccuucu gcuucgcauc cggacaaaac      180

aucaccgaag aauuuuacca gucaaccugc uccgcugucu caaaaggcua ccucucagcc      240

cuucgcaccg gcugguacac cucggucaua acaauagaac ucuccaauau caaagaaaac      300

aaaugcaacg gcacugacgc caagguaaaa cucaucaaac aggaacucga uaaauacaag      360

aacgccguaa cagaacuaca acuacucaug caaucaacac cggccaccgg cuccgguucc      420

gccauaugcu ccggaguggc cgugugcaag guccuccacc uugaagggga aguuaacaaa      480

aucaaaucag cccuccucuc cacuaacaaa gccguaguau cccuaagcaa cgguguaucc      540

guccucaccu ucaaaguacu agaccuaaag aauuauaucg acaaacaacu ccuccccaua      600

cucaacaaac aauccugcuc cauaagcaac aucgaaacag ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau aacccgcgag uucucaguca acgccggagu caccacaccc      720

gucagcaccu acaugcugac caacuccgaa cuccucuccu uaaucaauga caugcccauc      780

accaaugacc aaaagaaacu caugucaaac aacguccaaa uaguacgcca acaauccuac      840

uccaucaugu gcaucauaaa agaagaagua cucgccuacg ucguccaacu cccccucuac      900

ggcguaaucg acacccccug cuggaaacua cacacaagcc cccucugcac cacaaacacu      960

aaagagggcu ccaacaucug ucuaacccgc accgaucgag gcugguacug cgacaacgcc     1020

ggaucugucu cauucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucgag aacccucccu uccgaaguca accuaugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accucgaaaa ccgacguauc auccagcguc     1200

aucaccagcc uaggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgcgagcaau     1260

aaaaaccgcg ggaucaucaa aacuuucucc aacggcugcg acuacgucuc caacaaggga     1320

gucgauaccg ucuccguagg caacacccuc uacugcguca acaaacaaga aggcaaauca     1380

cuauacguaa aaggcgagcc aaucauaaac uucuacgacc cucuaguuuu cccauccgac     1440

gaguucgacg cuagcaucuc ccaagucaac gagaaaauca accaaucccu cgcauucauc     1500

cgcaaauccg acgaacuccu ccacaacgua aacgcaggca aaucaacuac uaauauaaug     1560

aucacaacca ucauaauagu cauaaucgua auccuccuau cccucaucgc cgucggacua     1620

cugcucuacu gcaaagcccg cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5094
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5094
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5095
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5095
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5096
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5096
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5097
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5097
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5098
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5098
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5099
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5099
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5100
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5100
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacuaaa agcuaacgcc      120

auaaccacua uacuaacagc agucacauuc ugcuucgcau caggccaaaa cauaaccgaa      180

gaauuuuacc aauccacuug uucagcaguc uccaaaggau auuuauccgc acuucguaca      240

ggaugguaua caucaguaau aacaauagaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg caaaaguaaa acucaucaaa caagaauuag acaaauacaa gaacgccgua      360

acagaacuac aauuacuaau gcaaucaaca cccgccacag gaucaggauc ugcaauaugc      420

ucuggaguag caguaugcaa aguauuacac cuagaaggag aaguaaacaa aaucaaaagc      480

gcacuacuau ccacaaacaa agcuguagua ucacuaucaa acggaguauc aguauuaacu      540

uucaaaguac uugaucuaaa aaacuacaua gacaaacaac uacuacccau auuaaacaaa      600

caaucaugcu caauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuacuagaaa ucacaaggga auuuucagua aaugccggug uuacaacccc aguaucaaca      720

uacaugcuaa cuaacucaga acuacuaucc uuaauaaacg auaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auaguaagac aacaaucaua cucaaucaug      840

ugcauuauaa aagaagaagu cuuagcauac guaguacaau uaccacuaua cgguguaaua      900

gauacaccau guuggaaauu acacacaagc ccacuaugca caacuaacac aaaagaaggc      960

ucaaauauau guuuaacaag aacagaccga gguugguacu gcgacaaugc aggaucagua     1020

ucauucuuuc cacaagcaga aacauguaaa guucaaucca acagaguauu cugcgacaca     1080

augaacucca gaacacuacc uucagaagua aaccucugua acguagacau auuuaauccc     1140

aaguacgacu gcaaaauaau gacaucgaaa acagacguaa gcuccucagu gauaacaucc     1200

cucggcgcca ucguauccug uuacgguaaa acuaaaugua ccgccucaaa caaaaaccgc     1260

gguauuauaa aaacuuuuuc uaauggcugc gauuacguaa gcaacaaagg cgucgacaca     1320

guuuccguag gaaacacacu auacugcgua aacaaacaag aagguaaauc ucuauacgua     1380

aaaggagaac caauaauaaa uuucuaugau ccuuuaguau ucccauccga ugaauuugac     1440

gccucuaucu cacaagucaa cgaaaaaaua aaucaaucau uagcauucau acgaaaauca     1500

gacgaacuac uacacaacgu aaacgcagga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaauag uuauuauagu gauacuauua uccuuaauug cagucggacu auuauuauac     1620

uguaaagcac gcuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5101
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5101
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaaugcc      120

aucaccacaa uccugacagc aguaaccuuc ugcuucgcau ccggacaaaa caucaccgaa      180

gaauuuuacc agucaaccug cuccgcuguc ucaaaaggcu accucucagc ccuucgcacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaua ucaaagaaaa caaaugcaac      300

ggcacugacg ccaagguaaa acucaucaaa caggaacucg auaaauacaa gaacgccgua      360

acagaacuac aacuacucau gcaaucaaca ccggccaccg gcuccgguuc cgccauaugc      420

uccggagugg ccgugugcaa gguccuccac cuugaagggg aaguuaacaa aaucaaauca      480

gcccuccucu ccacuaacaa agccguagua ucccuaagca acgguguauc cguccucacc      540

uucaaaguac uagaccuaaa gaauuauauc gacaaacaac uccuccccau acucaacaaa      600

caauccugcu ccauaagcaa caucgaaaca gucaucgagu uccagcagaa aaacaaccga      660

cuccucgaaa uaacccgcga guucucaguc aacgccggag ucaccacacc cgucagcacc      720

uacaugcuga ccaacuccga acuccucucc uuaaucaaug acaugcccau caccaaugac      780

caaaagaaac ucaugucaaa caacguccaa auaguacgcc aacaauccua cuccaucaug      840

ugcaucauaa aagaagaagu acucgccuac gucguccaac ucccccucua cggcguaauc      900

gacacccccu gcuggaaacu acacacaagc ccccucugca ccacaaacac uaaagagggc      960

uccaacaucu gucuaacccg caccgaucga ggcugguacu gcgacaacgc cggaucuguc     1020

ucauucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucga gaacccuccc uuccgaaguc aaccuaugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccucgaaa accgacguau cauccagcgu caucaccagc     1200

cuaggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgcgagcaa uaaaaaccgc     1260

gggaucauca aaacuuucuc caacggcugc gacuacgucu ccaacaaggg agucgauacc     1320

gucuccguag gcaacacccu cuacugcguc aacaaacaag aaggcaaauc acuauacgua     1380

aaaggcgagc caaucauaaa cuucuacgac ccucuaguuu ucccauccga cgaguucgac     1440

gcuagcaucu cccaagucaa cgagaaaauc aaccaauccc ucgcauucau ccgcaaaucc     1500

gacgaacucc uccacaacgu aaacgcaggc aaaucaacua cuaauauaau gaucacaacc     1560

aucauaauag ucauaaucgu aauccuccua ucccucaucg ccgucggacu acugcucuac     1620

ugcaaagccc gcuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  5102
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5102
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5103
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5103
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5104
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5104
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5105
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5105
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5106
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5106
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5107
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5107
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5108
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5108
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac uaaaagcuaa cgccauaacc acuauacuaa cagcagucac auucugcuuc      240

gcaucaggcc aaaacauaac cgaagaauuu uaccaaucca cuuguucagc agucuccaaa      300

ggauauuuau ccgcacuucg uacaggaugg uauacaucag uaauaacaau agaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgcaaaag uaaaacucau caaacaagaa      420

uuagacaaau acaagaacgc cguaacagaa cuacaauuac uaaugcaauc aacacccgcc      480

acaggaucag gaucugcaau augcucugga guagcaguau gcaaaguauu acaccuagaa      540

ggagaaguaa acaaaaucaa aagcgcacua cuauccacaa acaaagcugu aguaucacua      600

ucaaacggag uaucaguauu aacuuucaaa guacuugauc uaaaaaacua cauagacaaa      660

caacuacuac ccauauuaaa caaacaauca ugcucaauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuacua gaaaucacaa gggaauuuuc aguaaaugcc      780

gguguuacaa ccccaguauc aacauacaug cuaacuaacu cagaacuacu auccuuaaua      840

aacgauaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauacucaau caugugcauu auaaaagaag aagucuuagc auacguagua      960

caauuaccac uauacggugu aauagauaca ccauguugga aauuacacac aagcccacua     1020

ugcacaacua acacaaaaga aggcucaaau auauguuuaa caagaacaga ccgagguugg     1080

uacugcgaca augcaggauc aguaucauuc uuuccacaag cagaaacaug uaaaguucaa     1140

uccaacagag uauucugcga cacaaugaac uccagaacac uaccuucaga aguaaaccuc     1200

uguaacguag acauauuuaa ucccaaguac gacugcaaaa uaaugacauc gaaaacagac     1260

guaagcuccu cagugauaac aucccucggc gccaucguau ccuguuacgg uaaaacuaaa     1320

uguaccgccu caaacaaaaa ccgcgguauu auaaaaacuu uuucuaaugg cugcgauuac     1380

guaagcaaca aaggcgucga cacaguuucc guaggaaaca cacuauacug cguaaacaaa     1440

caagaaggua aaucucuaua cguaaaagga gaaccaauaa uaaauuucua ugauccuuua     1500

guauucccau ccgaugaauu ugacgccucu aucucacaag ucaacgaaaa aauaaaucaa     1560

ucauuagcau ucauacgaaa aucagacgaa cuacuacaca acguaaacgc aggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua auaguuauua uagugauacu auuauccuua     1680

auugcagucg gacuauuauu auacuguaaa gcacgcuaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5109
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5109
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa ugccaucacc acaauccuga cagcaguaac cuucugcuuc      240

gcauccggac aaaacaucac cgaagaauuu uaccagucaa ccugcuccgc ugucucaaaa      300

ggcuaccucu cagcccuucg caccggcugg uacaccucgg ucauaacaau agaacucucc      360

aauaucaaag aaaacaaaug caacggcacu gacgccaagg uaaaacucau caaacaggaa      420

cucgauaaau acaagaacgc cguaacagaa cuacaacuac ucaugcaauc aacaccggcc      480

accggcuccg guuccgccau augcuccgga guggccgugu gcaagguccu ccaccuugaa      540

ggggaaguua acaaaaucaa aucagcccuc cucuccacua acaaagccgu aguaucccua      600

agcaacggug uauccguccu caccuucaaa guacuagacc uaaagaauua uaucgacaaa      660

caacuccucc ccauacucaa caaacaaucc ugcuccauaa gcaacaucga aacagucauc      720

gaguuccagc agaaaaacaa ccgacuccuc gaaauaaccc gcgaguucuc agucaacgcc      780

ggagucacca cacccgucag caccuacaug cugaccaacu ccgaacuccu cuccuuaauc      840

aaugacaugc ccaucaccaa ugaccaaaag aaacucaugu caaacaacgu ccaaauagua      900

cgccaacaau ccuacuccau caugugcauc auaaaagaag aaguacucgc cuacgucguc      960

caacuccccc ucuacggcgu aaucgacacc cccugcugga aacuacacac aagcccccuc     1020

ugcaccacaa acacuaaaga gggcuccaac aucugucuaa cccgcaccga ucgaggcugg     1080

uacugcgaca acgccggauc ugucucauuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucgagaaccc ucccuuccga agucaaccua     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc gaaaaccgac     1260

guaucaucca gcgucaucac cagccuaggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgcga gcaauaaaaa ccgcgggauc aucaaaacuu ucuccaacgg cugcgacuac     1380

gucuccaaca agggagucga uaccgucucc guaggcaaca cccucuacug cgucaacaaa     1440

caagaaggca aaucacuaua cguaaaaggc gagccaauca uaaacuucua cgacccucua     1500

guuuucccau ccgacgaguu cgacgcuagc aucucccaag ucaacgagaa aaucaaccaa     1560

ucccucgcau ucauccgcaa auccgacgaa cuccuccaca acguaaacgc aggcaaauca     1620

acuacuaaua uaaugaucac aaccaucaua auagucauaa ucguaauccu ccuaucccuc     1680

aucgccgucg gacuacugcu cuacugcaaa gcccgcuaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  5110
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5110
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5111
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5111
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5112
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5112
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5113
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5113
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5114
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5114
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5115
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5115
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5116
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5116
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacuaaaagc uaacgccaua accacuauac      120

uaacagcagu cacauucugc uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau      180

ccacuuguuc agcagucucc aaaggauauu uauccgcacu ucguacagga ugguauacau      240

caguaauaac aauagaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcaa      300

aaguaaaacu caucaaacaa gaauuagaca aauacaagaa cgccguaaca gaacuacaau      360

uacuaaugca aucaacaccc gccacaggau caggaucugc aauaugcucu ggaguagcag      420

uaugcaaagu auuacaccua gaaggagaag uaaacaaaau caaaagcgca cuacuaucca      480

caaacaaagc uguaguauca cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug      540

aucuaaaaaa cuacauagac aaacaacuac uacccauauu aaacaaacaa ucaugcucaa      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua cuagaaauca      660

caagggaauu uucaguaaau gccgguguua caaccccagu aucaacauac augcuaacua      720

acucagaacu acuauccuua auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauacuc aaucaugugc auuauaaaag      840

aagaagucuu agcauacgua guacaauuac cacuauacgg uguaauagau acaccauguu      900

ggaaauuaca cacaagccca cuaugcacaa cuaacacaaa agaaggcuca aauauauguu      960

uaacaagaac agaccgaggu ugguacugcg acaaugcagg aucaguauca uucuuuccac     1020

aagcagaaac auguaaaguu caauccaaca gaguauucug cgacacaaug aacuccagaa     1080

cacuaccuuc agaaguaaac cucuguaacg uagacauauu uaaucccaag uacgacugca     1140

aaauaaugac aucgaaaaca gacguaagcu ccucagugau aacaucccuc ggcgccaucg     1200

uauccuguua cgguaaaacu aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa     1260

cuuuuucuaa uggcugcgau uacguaagca acaaaggcgu cgacacaguu uccguaggaa     1320

acacacuaua cugcguaaac aaacaagaag guaaaucucu auacguaaaa ggagaaccaa     1380

uaauaaauuu cuaugauccu uuaguauucc cauccgauga auuugacgcc ucuaucucac     1440

aagucaacga aaaaauaaau caaucauuag cauucauacg aaaaucagac gaacuacuac     1500

acaacguaaa cgcaggaaaa ucaacaacca acauaaugau aaccacaaua auaauaguua     1560

uuauagugau acuauuaucc uuaauugcag ucggacuauu auuauacugu aaagcacgcu     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5117
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5117
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caaugccauc accacaaucc      120

ugacagcagu aaccuucugc uucgcauccg gacaaaacau caccgaagaa uuuuaccagu      180

caaccugcuc cgcugucuca aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaauauca aagaaaacaa augcaacggc acugacgcca      300

agguaaaacu caucaaacag gaacucgaua aauacaagaa cgccguaaca gaacuacaac      360

uacucaugca aucaacaccg gccaccggcu ccgguuccgc cauaugcucc ggaguggccg      420

ugugcaaggu ccuccaccuu gaaggggaag uuaacaaaau caaaucagcc cuccucucca      480

cuaacaaagc cguaguaucc cuaagcaacg guguauccgu ccucaccuuc aaaguacuag      540

accuaaagaa uuauaucgac aaacaacucc uccccauacu caacaaacaa uccugcucca      600

uaagcaacau cgaaacaguc aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa      660

cccgcgaguu cucagucaac gccggaguca ccacacccgu cagcaccuac augcugacca      720

acuccgaacu ccucuccuua aucaaugaca ugcccaucac caaugaccaa aagaaacuca      780

ugucaaacaa cguccaaaua guacgccaac aauccuacuc caucaugugc aucauaaaag      840

aagaaguacu cgccuacguc guccaacucc cccucuacgg cguaaucgac acccccugcu      900

ggaaacuaca cacaagcccc cucugcacca caaacacuaa agagggcucc aacaucuguc      960

uaacccgcac cgaucgaggc ugguacugcg acaacgccgg aucugucuca uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucgagaa     1080

cccucccuuc cgaagucaac cuaugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cucgaaaacc gacguaucau ccagcgucau caccagccua ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa     1260

cuuucuccaa cggcugcgac uacgucucca acaagggagu cgauaccguc uccguaggca     1320

acacccucua cugcgucaac aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa     1380

ucauaaacuu cuacgacccu cuaguuuucc cauccgacga guucgacgcu agcaucuccc     1440

aagucaacga gaaaaucaac caaucccucg cauucauccg caaauccgac gaacuccucc     1500

acaacguaaa cgcaggcaaa ucaacuacua auauaaugau cacaaccauc auaauaguca     1560

uaaucguaau ccuccuaucc cucaucgccg ucggacuacu gcucuacugc aaagcccgcu     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  5118
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5118
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5119
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5119
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5120
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5120
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5121
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5121
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5122
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5122
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5123
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5123
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5124
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5124
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac uaaaagcuaa cgccauaacc acuauacuaa cagcagucac auucugcuuc      240

gcaucaggcc aaaacauaac cgaagaauuu uaccaaucca cuuguucagc agucuccaaa      300

ggauauuuau ccgcacuucg uacaggaugg uauacaucag uaauaacaau agaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgcaaaag uaaaacucau caaacaagaa      420

uuagacaaau acaagaacgc cguaacagaa cuacaauuac uaaugcaauc aacacccgcc      480

acaggaucag gaucugcaau augcucugga guagcaguau gcaaaguauu acaccuagaa      540

ggagaaguaa acaaaaucaa aagcgcacua cuauccacaa acaaagcugu aguaucacua      600

ucaaacggag uaucaguauu aacuuucaaa guacuugauc uaaaaaacua cauagacaaa      660

caacuacuac ccauauuaaa caaacaauca ugcucaauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuacua gaaaucacaa gggaauuuuc aguaaaugcc      780

gguguuacaa ccccaguauc aacauacaug cuaacuaacu cagaacuacu auccuuaaua      840

aacgauaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauacucaau caugugcauu auaaaagaag aagucuuagc auacguagua      960

caauuaccac uauacggugu aauagauaca ccauguugga aauuacacac aagcccacua     1020

ugcacaacua acacaaaaga aggcucaaau auauguuuaa caagaacaga ccgagguugg     1080

uacugcgaca augcaggauc aguaucauuc uuuccacaag cagaaacaug uaaaguucaa     1140

uccaacagag uauucugcga cacaaugaac uccagaacac uaccuucaga aguaaaccuc     1200

uguaacguag acauauuuaa ucccaaguac gacugcaaaa uaaugacauc gaaaacagac     1260

guaagcuccu cagugauaac aucccucggc gccaucguau ccuguuacgg uaaaacuaaa     1320

uguaccgccu caaacaaaaa ccgcgguauu auaaaaacuu uuucuaaugg cugcgauuac     1380

guaagcaaca aaggcgucga cacaguuucc guaggaaaca cacuauacug cguaaacaaa     1440

caagaaggua aaucucuaua cguaaaagga gaaccaauaa uaaauuucua ugauccuuua     1500

guauucccau ccgaugaauu ugacgccucu aucucacaag ucaacgaaaa aauaaaucaa     1560

ucauuagcau ucauacgaaa aucagacgaa cuacuacaca acguaaacgc aggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua auaguuauua uagugauacu auuauccuua     1680

auugcagucg gacuauuauu auacuguaaa gcacgcuaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5125
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5125
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa ugccaucacc acaauccuga cagcaguaac cuucugcuuc      240

gcauccggac aaaacaucac cgaagaauuu uaccagucaa ccugcuccgc ugucucaaaa      300

ggcuaccucu cagcccuucg caccggcugg uacaccucgg ucauaacaau agaacucucc      360

aauaucaaag aaaacaaaug caacggcacu gacgccaagg uaaaacucau caaacaggaa      420

cucgauaaau acaagaacgc cguaacagaa cuacaacuac ucaugcaauc aacaccggcc      480

accggcuccg guuccgccau augcuccgga guggccgugu gcaagguccu ccaccuugaa      540

ggggaaguua acaaaaucaa aucagcccuc cucuccacua acaaagccgu aguaucccua      600

agcaacggug uauccguccu caccuucaaa guacuagacc uaaagaauua uaucgacaaa      660

caacuccucc ccauacucaa caaacaaucc ugcuccauaa gcaacaucga aacagucauc      720

gaguuccagc agaaaaacaa ccgacuccuc gaaauaaccc gcgaguucuc agucaacgcc      780

ggagucacca cacccgucag caccuacaug cugaccaacu ccgaacuccu cuccuuaauc      840

aaugacaugc ccaucaccaa ugaccaaaag aaacucaugu caaacaacgu ccaaauagua      900

cgccaacaau ccuacuccau caugugcauc auaaaagaag aaguacucgc cuacgucguc      960

caacuccccc ucuacggcgu aaucgacacc cccugcugga aacuacacac aagcccccuc     1020

ugcaccacaa acacuaaaga gggcuccaac aucugucuaa cccgcaccga ucgaggcugg     1080

uacugcgaca acgccggauc ugucucauuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucgagaaccc ucccuuccga agucaaccua     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc gaaaaccgac     1260

guaucaucca gcgucaucac cagccuaggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgcga gcaauaaaaa ccgcgggauc aucaaaacuu ucuccaacgg cugcgacuac     1380

gucuccaaca agggagucga uaccgucucc guaggcaaca cccucuacug cgucaacaaa     1440

caagaaggca aaucacuaua cguaaaaggc gagccaauca uaaacuucua cgacccucua     1500

guuuucccau ccgacgaguu cgacgcuagc aucucccaag ucaacgagaa aaucaaccaa     1560

ucccucgcau ucauccgcaa auccgacgaa cuccuccaca acguaaacgc aggcaaauca     1620

acuacuaaua uaaugaucac aaccaucaua auagucauaa ucguaauccu ccuaucccuc     1680

aucgccgucg gacuacugcu cuacugcaaa gcccgcuaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  5126
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5126
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5127
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5127
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      480

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      540

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      600

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      720

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      960

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg     1020

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1080

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1140

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1260

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1320

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1380

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1620

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5128
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5128
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5129
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5129
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      480

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      540

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      600

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      660

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      720

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      780

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      840

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua      900

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca      960

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc     1020

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1080

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1140

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1200

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1260

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1320

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1380

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1440

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1500

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1560

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1620

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5130
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5130
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5131
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5131
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      480

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      540

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      600

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      660

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      720

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      780

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      840

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      900

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu      960

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga     1020

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1080

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1140

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1200

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1260

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1320

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1380

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1440

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1500

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1560

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1620

cugaucgccg ugggccuccu gcuguauugc aaagccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5132
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5132
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuuuuaa uacuaaaagc uaacgccaua accacuauac uaacagcagu cacauucugc      180

uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau ccacuuguuc agcagucucc      240

aaaggauauu uauccgcacu ucguacagga ugguauacau caguaauaac aauagaacuc      300

uccaacauaa aagaaaauaa augcaacggc accgacgcaa aaguaaaacu caucaaacaa      360

gaauuagaca aauacaagaa cgccguaaca gaacuacaau uacuaaugca aucaacaccc      420

gccacaggau caggaucugc aauaugcucu ggaguagcag uaugcaaagu auuacaccua      480

gaaggagaag uaaacaaaau caaaagcgca cuacuaucca caaacaaagc uguaguauca      540

cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug aucuaaaaaa cuacauagac      600

aaacaacuac uacccauauu aaacaaacaa ucaugcucaa uaagcaauau agaaacagua      660

auagaauuuc aacaaaaaaa caacagacua cuagaaauca caagggaauu uucaguaaau      720

gccgguguua caaccccagu aucaacauac augcuaacua acucagaacu acuauccuua      780

auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      840

guaagacaac aaucauacuc aaucaugugc auuauaaaag aagaagucuu agcauacgua      900

guacaauuac cacuauacgg uguaauagau acaccauguu ggaaauuaca cacaagccca      960

cuaugcacaa cuaacacaaa agaaggcuca aauauauguu uaacaagaac agaccgaggu     1020

ugguacugcg acaaugcagg aucaguauca uucuuuccac aagcagaaac auguaaaguu     1080

caauccaaca gaguauucug cgacacaaug aacuccagaa cacuaccuuc agaaguaaac     1140

cucuguaacg uagacauauu uaaucccaag uacgacugca aaauaaugac aucgaaaaca     1200

gacguaagcu ccucagugau aacaucccuc ggcgccaucg uauccuguua cgguaaaacu     1260

aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa cuuuuucuaa uggcugcgau     1320

uacguaagca acaaaggcgu cgacacaguu uccguaggaa acacacuaua cugcguaaac     1380

aaacaagaag guaaaucucu auacguaaaa ggagaaccaa uaauaaauuu cuaugauccu     1440

uuaguauucc cauccgauga auuugacgcc ucuaucucac aagucaacga aaaaauaaau     1500

caaucauuag cauucauacg aaaaucagac gaacuacuac acaacguaaa cgcaggaaaa     1560

ucaacaacca acauaaugau aaccacaaua auaauaguua uuauagugau acuauuaucc     1620

uuaauugcag ucggacuauu auuauacugu aaagcacgcu aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5133
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5133
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccucaaagc caaugccauc accacaaucc ugacagcagu aaccuucugc      180

uucgcauccg gacaaaacau caccgaagaa uuuuaccagu caaccugcuc cgcugucuca      240

aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu cggucauaac aauagaacuc      300

uccaauauca aagaaaacaa augcaacggc acugacgcca agguaaaacu caucaaacag      360

gaacucgaua aauacaagaa cgccguaaca gaacuacaac uacucaugca aucaacaccg      420

gccaccggcu ccgguuccgc cauaugcucc ggaguggccg ugugcaaggu ccuccaccuu      480

gaaggggaag uuaacaaaau caaaucagcc cuccucucca cuaacaaagc cguaguaucc      540

cuaagcaacg guguauccgu ccucaccuuc aaaguacuag accuaaagaa uuauaucgac      600

aaacaacucc uccccauacu caacaaacaa uccugcucca uaagcaacau cgaaacaguc      660

aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa cccgcgaguu cucagucaac      720

gccggaguca ccacacccgu cagcaccuac augcugacca acuccgaacu ccucuccuua      780

aucaaugaca ugcccaucac caaugaccaa aagaaacuca ugucaaacaa cguccaaaua      840

guacgccaac aauccuacuc caucaugugc aucauaaaag aagaaguacu cgccuacguc      900

guccaacucc cccucuacgg cguaaucgac acccccugcu ggaaacuaca cacaagcccc      960

cucugcacca caaacacuaa agagggcucc aacaucuguc uaacccgcac cgaucgaggc     1020

ugguacugcg acaacgccgg aucugucuca uucuuccccc aagccgaaac cugcaaaguc     1080

caauccaacc gcgucuucug cgacaccaug aacucgagaa cccucccuuc cgaagucaac     1140

cuaugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cucgaaaacc     1200

gacguaucau ccagcgucau caccagccua ggcgcaaucg ugagcugcua cggcaaaacc     1260

aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa cuuucuccaa cggcugcgac     1320

uacgucucca acaagggagu cgauaccguc uccguaggca acacccucua cugcgucaac     1380

aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa ucauaaacuu cuacgacccu     1440

cuaguuuucc cauccgacga guucgacgcu agcaucuccc aagucaacga gaaaaucaac     1500

caaucccucg cauucauccg caaauccgac gaacuccucc acaacguaaa cgcaggcaaa     1560

ucaacuacua auauaaugau cacaaccauc auaauaguca uaaucguaau ccuccuaucc     1620

cucaucgccg ucggacuacu gcucuacugc aaagcccgcu aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  5134
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5134
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5135
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5135
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5136
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5136
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5137
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5137
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5138
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5138
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5139
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5139
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5140
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5140
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacuaaaa      120

gcuaacgcca uaaccacuau acuaacagca gucacauucu gcuucgcauc aggccaaaac      180

auaaccgaag aauuuuacca auccacuugu ucagcagucu ccaaaggaua uuuauccgca      240

cuucguacag gaugguauac aucaguaaua acaauagaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc aaaaguaaaa cucaucaaac aagaauuaga caaauacaag      360

aacgccguaa cagaacuaca auuacuaaug caaucaacac ccgccacagg aucaggaucu      420

gcaauaugcu cuggaguagc aguaugcaaa guauuacacc uagaaggaga aguaaacaaa      480

aucaaaagcg cacuacuauc cacaaacaaa gcuguaguau cacuaucaaa cggaguauca      540

guauuaacuu ucaaaguacu ugaucuaaaa aacuacauag acaaacaacu acuacccaua      600

uuaaacaaac aaucaugcuc aauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uacuagaaau cacaagggaa uuuucaguaa augccggugu uacaacccca      720

guaucaacau acaugcuaac uaacucagaa cuacuauccu uaauaaacga uaugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauuauaaa agaagaaguc uuagcauacg uaguacaauu accacuauac      900

gguguaauag auacaccaug uuggaaauua cacacaagcc cacuaugcac aacuaacaca      960

aaagaaggcu caaauauaug uuuaacaaga acagaccgag guugguacug cgacaaugca     1020

ggaucaguau cauucuuucc acaagcagaa acauguaaag uucaauccaa cagaguauuc     1080

ugcgacacaa ugaacuccag aacacuaccu ucagaaguaa accucuguaa cguagacaua     1140

uuuaauccca aguacgacug caaaauaaug acaucgaaaa cagacguaag cuccucagug     1200

auaacauccc ucggcgccau cguauccugu uacgguaaaa cuaaauguac cgccucaaac     1260

aaaaaccgcg guauuauaaa aacuuuuucu aauggcugcg auuacguaag caacaaaggc     1320

gucgacacag uuuccguagg aaacacacua uacugcguaa acaaacaaga agguaaaucu     1380

cuauacguaa aaggagaacc aauaauaaau uucuaugauc cuuuaguauu cccauccgau     1440

gaauuugacg ccucuaucuc acaagucaac gaaaaaauaa aucaaucauu agcauucaua     1500

cgaaaaucag acgaacuacu acacaacgua aacgcaggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaauagu uauuauagug auacuauuau ccuuaauugc agucggacua     1620

uuauuauacu guaaagcacg cuaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5141
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5141
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaaugcca ucaccacaau ccugacagca guaaccuucu gcuucgcauc cggacaaaac      180

aucaccgaag aauuuuacca gucaaccugc uccgcugucu caaaaggcua ccucucagcc      240

cuucgcaccg gcugguacac cucggucaua acaauagaac ucuccaauau caaagaaaac      300

aaaugcaacg gcacugacgc caagguaaaa cucaucaaac aggaacucga uaaauacaag      360

aacgccguaa cagaacuaca acuacucaug caaucaacac cggccaccgg cuccgguucc      420

gccauaugcu ccggaguggc cgugugcaag guccuccacc uugaagggga aguuaacaaa      480

aucaaaucag cccuccucuc cacuaacaaa gccguaguau cccuaagcaa cgguguaucc      540

guccucaccu ucaaaguacu agaccuaaag aauuauaucg acaaacaacu ccuccccaua      600

cucaacaaac aauccugcuc cauaagcaac aucgaaacag ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau aacccgcgag uucucaguca acgccggagu caccacaccc      720

gucagcaccu acaugcugac caacuccgaa cuccucuccu uaaucaauga caugcccauc      780

accaaugacc aaaagaaacu caugucaaac aacguccaaa uaguacgcca acaauccuac      840

uccaucaugu gcaucauaaa agaagaagua cucgccuacg ucguccaacu cccccucuac      900

ggcguaaucg acacccccug cuggaaacua cacacaagcc cccucugcac cacaaacacu      960

aaagagggcu ccaacaucug ucuaacccgc accgaucgag gcugguacug cgacaacgcc     1020

ggaucugucu cauucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucgag aacccucccu uccgaaguca accuaugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accucgaaaa ccgacguauc auccagcguc     1200

aucaccagcc uaggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgcgagcaau     1260

aaaaaccgcg ggaucaucaa aacuuucucc aacggcugcg acuacgucuc caacaaggga     1320

gucgauaccg ucuccguagg caacacccuc uacugcguca acaaacaaga aggcaaauca     1380

cuauacguaa aaggcgagcc aaucauaaac uucuacgacc cucuaguuuu cccauccgac     1440

gaguucgacg cuagcaucuc ccaagucaac gagaaaauca accaaucccu cgcauucauc     1500

cgcaaauccg acgaacuccu ccacaacgua aacgcaggca aaucaacuac uaauauaaug     1560

aucacaacca ucauaauagu cauaaucgua auccuccuau cccucaucgc cgucggacua     1620

cugcucuacu gcaaagcccg cuaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5142
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5142
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5143
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5143
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5144
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5144
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5145
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5145
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5146
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5146
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5147
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5147
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5148
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5148
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacuaaaa gcuaacgcca uaaccacuau acuaacagca      120

gucacauucu gcuucgcauc aggccaaaac auaaccgaag aauuuuacca auccacuugu      180

ucagcagucu ccaaaggaua uuuauccgca cuucguacag gaugguauac aucaguaaua      240

acaauagaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc aaaaguaaaa      300

cucaucaaac aagaauuaga caaauacaag aacgccguaa cagaacuaca auuacuaaug      360

caaucaacac ccgccacagg aucaggaucu gcaauaugcu cuggaguagc aguaugcaaa      420

guauuacacc uagaaggaga aguaaacaaa aucaaaagcg cacuacuauc cacaaacaaa      480

gcuguaguau cacuaucaaa cggaguauca guauuaacuu ucaaaguacu ugaucuaaaa      540

aacuacauag acaaacaacu acuacccaua uuaaacaaac aaucaugcuc aauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uacuagaaau cacaagggaa      660

uuuucaguaa augccggugu uacaacccca guaucaacau acaugcuaac uaacucagaa      720

cuacuauccu uaauaaacga uaugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uaguaagaca acaaucauac ucaaucaugu gcauuauaaa agaagaaguc      840

uuagcauacg uaguacaauu accacuauac gguguaauag auacaccaug uuggaaauua      900

cacacaagcc cacuaugcac aacuaacaca aaagaaggcu caaauauaug uuuaacaaga      960

acagaccgag guugguacug cgacaaugca ggaucaguau cauucuuucc acaagcagaa     1020

acauguaaag uucaauccaa cagaguauuc ugcgacacaa ugaacuccag aacacuaccu     1080

ucagaaguaa accucuguaa cguagacaua uuuaauccca aguacgacug caaaauaaug     1140

acaucgaaaa cagacguaag cuccucagug auaacauccc ucggcgccau cguauccugu     1200

uacgguaaaa cuaaauguac cgccucaaac aaaaaccgcg guauuauaaa aacuuuuucu     1260

aauggcugcg auuacguaag caacaaaggc gucgacacag uuuccguagg aaacacacua     1320

uacugcguaa acaaacaaga agguaaaucu cuauacguaa aaggagaacc aauaauaaau     1380

uucuaugauc cuuuaguauu cccauccgau gaauuugacg ccucuaucuc acaagucaac     1440

gaaaaaauaa aucaaucauu agcauucaua cgaaaaucag acgaacuacu acacaacgua     1500

aacgcaggaa aaucaacaac caacauaaug auaaccacaa uaauaauagu uauuauagug     1560

auacuauuau ccuuaauugc agucggacua uuauuauacu guaaagcacg cuaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5149
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5149
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaaugcca ucaccacaau ccugacagca      120

guaaccuucu gcuucgcauc cggacaaaac aucaccgaag aauuuuacca gucaaccugc      180

uccgcugucu caaaaggcua ccucucagcc cuucgcaccg gcugguacac cucggucaua      240

acaauagaac ucuccaauau caaagaaaac aaaugcaacg gcacugacgc caagguaaaa      300

cucaucaaac aggaacucga uaaauacaag aacgccguaa cagaacuaca acuacucaug      360

caaucaacac cggccaccgg cuccgguucc gccauaugcu ccggaguggc cgugugcaag      420

guccuccacc uugaagggga aguuaacaaa aucaaaucag cccuccucuc cacuaacaaa      480

gccguaguau cccuaagcaa cgguguaucc guccucaccu ucaaaguacu agaccuaaag      540

aauuauaucg acaaacaacu ccuccccaua cucaacaaac aauccugcuc cauaagcaac      600

aucgaaacag ucaucgaguu ccagcagaaa aacaaccgac uccucgaaau aacccgcgag      660

uucucaguca acgccggagu caccacaccc gucagcaccu acaugcugac caacuccgaa      720

cuccucuccu uaaucaauga caugcccauc accaaugacc aaaagaaacu caugucaaac      780

aacguccaaa uaguacgcca acaauccuac uccaucaugu gcaucauaaa agaagaagua      840

cucgccuacg ucguccaacu cccccucuac ggcguaaucg acacccccug cuggaaacua      900

cacacaagcc cccucugcac cacaaacacu aaagagggcu ccaacaucug ucuaacccgc      960

accgaucgag gcugguacug cgacaacgcc ggaucugucu cauucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucgag aacccucccu     1080

uccgaaguca accuaugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accucgaaaa ccgacguauc auccagcguc aucaccagcc uaggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgcgagcaau aaaaaccgcg ggaucaucaa aacuuucucc     1260

aacggcugcg acuacgucuc caacaaggga gucgauaccg ucuccguagg caacacccuc     1320

uacugcguca acaaacaaga aggcaaauca cuauacguaa aaggcgagcc aaucauaaac     1380

uucuacgacc cucuaguuuu cccauccgac gaguucgacg cuagcaucuc ccaagucaac     1440

gagaaaauca accaaucccu cgcauucauc cgcaaauccg acgaacuccu ccacaacgua     1500

aacgcaggca aaucaacuac uaauauaaug aucacaacca ucauaauagu cauaaucgua     1560

auccuccuau cccucaucgc cgucggacua cugcucuacu gcaaagcccg cuaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  5150
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5150
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5151
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5151
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5152
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5152
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5153
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5153
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5154
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5154
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5155
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5155
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5156
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5156
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu aaaagcuaac gccauaacca cuauacuaac agcagucaca      180

uucugcuucg caucaggcca aaacauaacc gaagaauuuu accaauccac uuguucagca      240

gucuccaaag gauauuuauc cgcacuucgu acaggauggu auacaucagu aauaacaaua      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgcaaaagu aaaacucauc      360

aaacaagaau uagacaaaua caagaacgcc guaacagaac uacaauuacu aaugcaauca      420

acacccgcca caggaucagg aucugcaaua ugcucuggag uagcaguaug caaaguauua      480

caccuagaag gagaaguaaa caaaaucaaa agcgcacuac uauccacaaa caaagcugua      540

guaucacuau caaacggagu aucaguauua acuuucaaag uacuugaucu aaaaaacuac      600

auagacaaac aacuacuacc cauauuaaac aaacaaucau gcucaauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuacuag aaaucacaag ggaauuuuca      720

guaaaugccg guguuacaac cccaguauca acauacaugc uaacuaacuc agaacuacua      780

uccuuaauaa acgauaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguaa gacaacaauc auacucaauc augugcauua uaaaagaaga agucuuagca      900

uacguaguac aauuaccacu auacggugua auagauacac cauguuggaa auuacacaca      960

agcccacuau gcacaacuaa cacaaaagaa ggcucaaaua uauguuuaac aagaacagac     1020

cgagguuggu acugcgacaa ugcaggauca guaucauucu uuccacaagc agaaacaugu     1080

aaaguucaau ccaacagagu auucugcgac acaaugaacu ccagaacacu accuucagaa     1140

guaaaccucu guaacguaga cauauuuaau cccaaguacg acugcaaaau aaugacaucg     1200

aaaacagacg uaagcuccuc agugauaaca ucccucggcg ccaucguauc cuguuacggu     1260

aaaacuaaau guaccgccuc aaacaaaaac cgcgguauua uaaaaacuuu uucuaauggc     1320

ugcgauuacg uaagcaacaa aggcgucgac acaguuuccg uaggaaacac acuauacugc     1380

guaaacaaac aagaagguaa aucucuauac guaaaaggag aaccaauaau aaauuucuau     1440

gauccuuuag uauucccauc cgaugaauuu gacgccucua ucucacaagu caacgaaaaa     1500

auaaaucaau cauuagcauu cauacgaaaa ucagacgaac uacuacacaa cguaaacgca     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa uaguuauuau agugauacua     1620

uuauccuuaa uugcagucgg acuauuauua uacuguaaag cacgcuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5157
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5157
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaau gccaucacca caauccugac agcaguaacc      180

uucugcuucg cauccggaca aaacaucacc gaagaauuuu accagucaac cugcuccgcu      240

gucucaaaag gcuaccucuc agcccuucgc accggcuggu acaccucggu cauaacaaua      300

gaacucucca auaucaaaga aaacaaaugc aacggcacug acgccaaggu aaaacucauc      360

aaacaggaac ucgauaaaua caagaacgcc guaacagaac uacaacuacu caugcaauca      420

acaccggcca ccggcuccgg uuccgccaua ugcuccggag uggccgugug caagguccuc      480

caccuugaag gggaaguuaa caaaaucaaa ucagcccucc ucuccacuaa caaagccgua      540

guaucccuaa gcaacggugu auccguccuc accuucaaag uacuagaccu aaagaauuau      600

aucgacaaac aacuccuccc cauacucaac aaacaauccu gcuccauaag caacaucgaa      660

acagucaucg aguuccagca gaaaaacaac cgacuccucg aaauaacccg cgaguucuca      720

gucaacgccg gagucaccac acccgucagc accuacaugc ugaccaacuc cgaacuccuc      780

uccuuaauca augacaugcc caucaccaau gaccaaaaga aacucauguc aaacaacguc      840

caaauaguac gccaacaauc cuacuccauc augugcauca uaaaagaaga aguacucgcc      900

uacgucgucc aacucccccu cuacggcgua aucgacaccc ccugcuggaa acuacacaca      960

agcccccucu gcaccacaaa cacuaaagag ggcuccaaca ucugucuaac ccgcaccgau     1020

cgaggcuggu acugcgacaa cgccggaucu gucucauucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cgagaacccu cccuuccgaa     1140

gucaaccuau gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucg     1200

aaaaccgacg uaucauccag cgucaucacc agccuaggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgcgag caauaaaaac cgcgggauca ucaaaacuuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggagucgau accgucuccg uaggcaacac ccucuacugc     1380

gucaacaaac aagaaggcaa aucacuauac guaaaaggcg agccaaucau aaacuucuac     1440

gacccucuag uuuucccauc cgacgaguuc gacgcuagca ucucccaagu caacgagaaa     1500

aucaaccaau cccucgcauu cauccgcaaa uccgacgaac uccuccacaa cguaaacgca     1560

ggcaaaucaa cuacuaauau aaugaucaca accaucauaa uagucauaau cguaauccuc     1620

cuaucccuca ucgccgucgg acuacugcuc uacugcaaag cccgcuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5158
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5158
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5159
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5159
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5160
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5160
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5161
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5161
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5162
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5162
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5163
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5163
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5164
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5164
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacuaaa agcuaacgcc      120

auaaccacua uacuaacagc agucacauuc ugcuucgcau caggccaaaa cauaaccgaa      180

gaauuuuacc aauccacuug uucagcaguc uccaaaggau auuuauccgc acuucguaca      240

ggaugguaua caucaguaau aacaauagaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg caaaaguaaa acucaucaaa caagaauuag acaaauacaa gaacgccgua      360

acagaacuac aauuacuaau gcaaucaaca cccgccacag gaucaggauc ugcaauaugc      420

ucuggaguag caguaugcaa aguauuacac cuagaaggag aaguaaacaa aaucaaaagc      480

gcacuacuau ccacaaacaa agcuguagua ucacuaucaa acggaguauc aguauuaacu      540

uucaaaguac uugaucuaaa aaacuacaua gacaaacaac uacuacccau auuaaacaaa      600

caaucaugcu caauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuacuagaaa ucacaaggga auuuucagua aaugccggug uuacaacccc aguaucaaca      720

uacaugcuaa cuaacucaga acuacuaucc uuaauaaacg auaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auaguaagac aacaaucaua cucaaucaug      840

ugcauuauaa aagaagaagu cuuagcauac guaguacaau uaccacuaua cgguguaaua      900

gauacaccau guuggaaauu acacacaagc ccacuaugca caacuaacac aaaagaaggc      960

ucaaauauau guuuaacaag aacagaccga gguugguacu gcgacaaugc aggaucagua     1020

ucauucuuuc cacaagcaga aacauguaaa guucaaucca acagaguauu cugcgacaca     1080

augaacucca gaacacuacc uucagaagua aaccucugua acguagacau auuuaauccc     1140

aaguacgacu gcaaaauaau gacaucgaaa acagacguaa gcuccucagu gauaacaucc     1200

cucggcgcca ucguauccug uuacgguaaa acuaaaugua ccgccucaaa caaaaaccgc     1260

gguauuauaa aaacuuuuuc uaauggcugc gauuacguaa gcaacaaagg cgucgacaca     1320

guuuccguag gaaacacacu auacugcgua aacaaacaag aagguaaauc ucuauacgua     1380

aaaggagaac caauaauaaa uuucuaugau ccuuuaguau ucccauccga ugaauuugac     1440

gccucuaucu cacaagucaa cgaaaaaaua aaucaaucau uagcauucau acgaaaauca     1500

gacgaacuac uacacaacgu aaacgcagga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaauag uuauuauagu gauacuauua uccuuaauug cagucggacu auuauuauac     1620

uguaaagcac gcuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5165
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5165
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaaugcc      120

aucaccacaa uccugacagc aguaaccuuc ugcuucgcau ccggacaaaa caucaccgaa      180

gaauuuuacc agucaaccug cuccgcuguc ucaaaaggcu accucucagc ccuucgcacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaua ucaaagaaaa caaaugcaac      300

ggcacugacg ccaagguaaa acucaucaaa caggaacucg auaaauacaa gaacgccgua      360

acagaacuac aacuacucau gcaaucaaca ccggccaccg gcuccgguuc cgccauaugc      420

uccggagugg ccgugugcaa gguccuccac cuugaagggg aaguuaacaa aaucaaauca      480

gcccuccucu ccacuaacaa agccguagua ucccuaagca acgguguauc cguccucacc      540

uucaaaguac uagaccuaaa gaauuauauc gacaaacaac uccuccccau acucaacaaa      600

caauccugcu ccauaagcaa caucgaaaca gucaucgagu uccagcagaa aaacaaccga      660

cuccucgaaa uaacccgcga guucucaguc aacgccggag ucaccacacc cgucagcacc      720

uacaugcuga ccaacuccga acuccucucc uuaaucaaug acaugcccau caccaaugac      780

caaaagaaac ucaugucaaa caacguccaa auaguacgcc aacaauccua cuccaucaug      840

ugcaucauaa aagaagaagu acucgccuac gucguccaac ucccccucua cggcguaauc      900

gacacccccu gcuggaaacu acacacaagc ccccucugca ccacaaacac uaaagagggc      960

uccaacaucu gucuaacccg caccgaucga ggcugguacu gcgacaacgc cggaucuguc     1020

ucauucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucga gaacccuccc uuccgaaguc aaccuaugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccucgaaa accgacguau cauccagcgu caucaccagc     1200

cuaggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgcgagcaa uaaaaaccgc     1260

gggaucauca aaacuuucuc caacggcugc gacuacgucu ccaacaaggg agucgauacc     1320

gucuccguag gcaacacccu cuacugcguc aacaaacaag aaggcaaauc acuauacgua     1380

aaaggcgagc caaucauaaa cuucuacgac ccucuaguuu ucccauccga cgaguucgac     1440

gcuagcaucu cccaagucaa cgagaaaauc aaccaauccc ucgcauucau ccgcaaaucc     1500

gacgaacucc uccacaacgu aaacgcaggc aaaucaacua cuaauauaau gaucacaacc     1560

aucauaauag ucauaaucgu aauccuccua ucccucaucg ccgucggacu acugcucuac     1620

ugcaaagccc gcuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  5166
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5166
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5167
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5167
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5168
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5168
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5169
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5169
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5170
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5170
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5171
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5171
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5172
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5172
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacuaaa agcuaacgcc      120

auaaccacua uacuaacagc agucacauuc ugcuucgcau caggccaaaa cauaaccgaa      180

gaauuuuacc aauccacuug uucagcaguc uccaaaggau auuuauccgc acuucguaca      240

ggaugguaua caucaguaau aacaauagaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg caaaaguaaa acucaucaaa caagaauuag acaaauacaa gaacgccgua      360

acagaacuac aauuacuaau gcaaucaaca cccgccacag gaucaggauc ugcaauaugc      420

ucuggaguag caguaugcaa aguauuacac cuagaaggag aaguaaacaa aaucaaaagc      480

gcacuacuau ccacaaacaa agcuguagua ucacuaucaa acggaguauc aguauuaacu      540

uucaaaguac uugaucuaaa aaacuacaua gacaaacaac uacuacccau auuaaacaaa      600

caaucaugcu caauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuacuagaaa ucacaaggga auuuucagua aaugccggug uuacaacccc aguaucaaca      720

uacaugcuaa cuaacucaga acuacuaucc uuaauaaacg auaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auaguaagac aacaaucaua cucaaucaug      840

ugcauuauaa aagaagaagu cuuagcauac guaguacaau uaccacuaua cgguguaaua      900

gauacaccau guuggaaauu acacacaagc ccacuaugca caacuaacac aaaagaaggc      960

ucaaauauau guuuaacaag aacagaccga gguugguacu gcgacaaugc aggaucagua     1020

ucauucuuuc cacaagcaga aacauguaaa guucaaucca acagaguauu cugcgacaca     1080

augaacucca gaacacuacc uucagaagua aaccucugua acguagacau auuuaauccc     1140

aaguacgacu gcaaaauaau gacaucgaaa acagacguaa gcuccucagu gauaacaucc     1200

cucggcgcca ucguauccug uuacgguaaa acuaaaugua ccgccucaaa caaaaaccgc     1260

gguauuauaa aaacuuuuuc uaauggcugc gauuacguaa gcaacaaagg cgucgacaca     1320

guuuccguag gaaacacacu auacugcgua aacaaacaag aagguaaauc ucuauacgua     1380

aaaggagaac caauaauaaa uuucuaugau ccuuuaguau ucccauccga ugaauuugac     1440

gccucuaucu cacaagucaa cgaaaaaaua aaucaaucau uagcauucau acgaaaauca     1500

gacgaacuac uacacaacgu aaacgcagga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaauag uuauuauagu gauacuauua uccuuaauug cagucggacu auuauuauac     1620

uguaaagcac gcuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5173
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5173
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaaugcc      120

aucaccacaa uccugacagc aguaaccuuc ugcuucgcau ccggacaaaa caucaccgaa      180

gaauuuuacc agucaaccug cuccgcuguc ucaaaaggcu accucucagc ccuucgcacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaua ucaaagaaaa caaaugcaac      300

ggcacugacg ccaagguaaa acucaucaaa caggaacucg auaaauacaa gaacgccgua      360

acagaacuac aacuacucau gcaaucaaca ccggccaccg gcuccgguuc cgccauaugc      420

uccggagugg ccgugugcaa gguccuccac cuugaagggg aaguuaacaa aaucaaauca      480

gcccuccucu ccacuaacaa agccguagua ucccuaagca acgguguauc cguccucacc      540

uucaaaguac uagaccuaaa gaauuauauc gacaaacaac uccuccccau acucaacaaa      600

caauccugcu ccauaagcaa caucgaaaca gucaucgagu uccagcagaa aaacaaccga      660

cuccucgaaa uaacccgcga guucucaguc aacgccggag ucaccacacc cgucagcacc      720

uacaugcuga ccaacuccga acuccucucc uuaaucaaug acaugcccau caccaaugac      780

caaaagaaac ucaugucaaa caacguccaa auaguacgcc aacaauccua cuccaucaug      840

ugcaucauaa aagaagaagu acucgccuac gucguccaac ucccccucua cggcguaauc      900

gacacccccu gcuggaaacu acacacaagc ccccucugca ccacaaacac uaaagagggc      960

uccaacaucu gucuaacccg caccgaucga ggcugguacu gcgacaacgc cggaucuguc     1020

ucauucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucga gaacccuccc uuccgaaguc aaccuaugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccucgaaa accgacguau cauccagcgu caucaccagc     1200

cuaggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgcgagcaa uaaaaaccgc     1260

gggaucauca aaacuuucuc caacggcugc gacuacgucu ccaacaaggg agucgauacc     1320

gucuccguag gcaacacccu cuacugcguc aacaaacaag aaggcaaauc acuauacgua     1380

aaaggcgagc caaucauaaa cuucuacgac ccucuaguuu ucccauccga cgaguucgac     1440

gcuagcaucu cccaagucaa cgagaaaauc aaccaauccc ucgcauucau ccgcaaaucc     1500

gacgaacucc uccacaacgu aaacgcaggc aaaucaacua cuaauauaau gaucacaacc     1560

aucauaauag ucauaaucgu aauccuccua ucccucaucg ccgucggacu acugcucuac     1620

ugcaaagccc gcuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  5174
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5174
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5175
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5175
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5176
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5176
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5177
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5177
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5178
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5178
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5179
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5179
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5180
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5180
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacuaaa agcuaacgcc      120

auaaccacua uacuaacagc agucacauuc ugcuucgcau caggccaaaa cauaaccgaa      180

gaauuuuacc aauccacuug uucagcaguc uccaaaggau auuuauccgc acuucguaca      240

ggaugguaua caucaguaau aacaauagaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg caaaaguaaa acucaucaaa caagaauuag acaaauacaa gaacgccgua      360

acagaacuac aauuacuaau gcaaucaaca cccgccacag gaucaggauc ugcaauaugc      420

ucuggaguag caguaugcaa aguauuacac cuagaaggag aaguaaacaa aaucaaaagc      480

gcacuacuau ccacaaacaa agcuguagua ucacuaucaa acggaguauc aguauuaacu      540

uucaaaguac uugaucuaaa aaacuacaua gacaaacaac uacuacccau auuaaacaaa      600

caaucaugcu caauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuacuagaaa ucacaaggga auuuucagua aaugccggug uuacaacccc aguaucaaca      720

uacaugcuaa cuaacucaga acuacuaucc uuaauaaacg auaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auaguaagac aacaaucaua cucaaucaug      840

ugcauuauaa aagaagaagu cuuagcauac guaguacaau uaccacuaua cgguguaaua      900

gauacaccau guuggaaauu acacacaagc ccacuaugca caacuaacac aaaagaaggc      960

ucaaauauau guuuaacaag aacagaccga gguugguacu gcgacaaugc aggaucagua     1020

ucauucuuuc cacaagcaga aacauguaaa guucaaucca acagaguauu cugcgacaca     1080

augaacucca gaacacuacc uucagaagua aaccucugua acguagacau auuuaauccc     1140

aaguacgacu gcaaaauaau gacaucgaaa acagacguaa gcuccucagu gauaacaucc     1200

cucggcgcca ucguauccug uuacgguaaa acuaaaugua ccgccucaaa caaaaaccgc     1260

gguauuauaa aaacuuuuuc uaauggcugc gauuacguaa gcaacaaagg cgucgacaca     1320

guuuccguag gaaacacacu auacugcgua aacaaacaag aagguaaauc ucuauacgua     1380

aaaggagaac caauaauaaa uuucuaugau ccuuuaguau ucccauccga ugaauuugac     1440

gccucuaucu cacaagucaa cgaaaaaaua aaucaaucau uagcauucau acgaaaauca     1500

gacgaacuac uacacaacgu aaacgcagga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaauag uuauuauagu gauacuauua uccuuaauug cagucggacu auuauuauac     1620

uguaaagcac gcuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5181
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5181
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaaugcc      120

aucaccacaa uccugacagc aguaaccuuc ugcuucgcau ccggacaaaa caucaccgaa      180

gaauuuuacc agucaaccug cuccgcuguc ucaaaaggcu accucucagc ccuucgcacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaua ucaaagaaaa caaaugcaac      300

ggcacugacg ccaagguaaa acucaucaaa caggaacucg auaaauacaa gaacgccgua      360

acagaacuac aacuacucau gcaaucaaca ccggccaccg gcuccgguuc cgccauaugc      420

uccggagugg ccgugugcaa gguccuccac cuugaagggg aaguuaacaa aaucaaauca      480

gcccuccucu ccacuaacaa agccguagua ucccuaagca acgguguauc cguccucacc      540

uucaaaguac uagaccuaaa gaauuauauc gacaaacaac uccuccccau acucaacaaa      600

caauccugcu ccauaagcaa caucgaaaca gucaucgagu uccagcagaa aaacaaccga      660

cuccucgaaa uaacccgcga guucucaguc aacgccggag ucaccacacc cgucagcacc      720

uacaugcuga ccaacuccga acuccucucc uuaaucaaug acaugcccau caccaaugac      780

caaaagaaac ucaugucaaa caacguccaa auaguacgcc aacaauccua cuccaucaug      840

ugcaucauaa aagaagaagu acucgccuac gucguccaac ucccccucua cggcguaauc      900

gacacccccu gcuggaaacu acacacaagc ccccucugca ccacaaacac uaaagagggc      960

uccaacaucu gucuaacccg caccgaucga ggcugguacu gcgacaacgc cggaucuguc     1020

ucauucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucga gaacccuccc uuccgaaguc aaccuaugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccucgaaa accgacguau cauccagcgu caucaccagc     1200

cuaggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgcgagcaa uaaaaaccgc     1260

gggaucauca aaacuuucuc caacggcugc gacuacgucu ccaacaaggg agucgauacc     1320

gucuccguag gcaacacccu cuacugcguc aacaaacaag aaggcaaauc acuauacgua     1380

aaaggcgagc caaucauaaa cuucuacgac ccucuaguuu ucccauccga cgaguucgac     1440

gcuagcaucu cccaagucaa cgagaaaauc aaccaauccc ucgcauucau ccgcaaaucc     1500

gacgaacucc uccacaacgu aaacgcaggc aaaucaacua cuaauauaau gaucacaacc     1560

aucauaauag ucauaaucgu aauccuccua ucccucaucg ccgucggacu acugcucuac     1620

ugcaaagccc gcuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  5182
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5182
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucugc      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc     1080

augaacuccc ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaaccgg     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacugcgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5183
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5183
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucugc      420

agcggcgugg ccgugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcgcugcuga gcaccaacaa ggccgugguc ucccucagca acgggguguc cgugcugacg      540

uucaaggucc uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg      660

cugcuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuca ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ucccccugua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc      960

uccaacaucu gccugacccg caccgaccgg gggugguacu gcgacaacgc cggcuccgug     1020

agcuucuucc cccaggcgga gaccugcaag guccagucca accgcguguu cugcgacacg     1080

augaacagcc ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaaccgg     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu cuacugcguc aacaagcagg aggggaaguc ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagagc     1500

gacgagcugc ugcacaacgu gaacgcgggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5184
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5184
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucugc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc     1080

augaacuccc gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaaccgc     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacugcguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5185
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5185
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauaugu      420

agcggagugg cagucugcaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcccugcugu ccacgaauaa agcugugguc ucucucagca acgguguguc cguauuaacu      540

uuuaagguuc uggaccuuaa gaauuacauu gauaaacaau ugcugccuau ccuaaacaag      600

cagucaugua guauuagcaa uaucgagacc gugauagagu uccagcagaa aaacaauagg      660

cuccuggaaa uuacacggga guuuucuguc aacgccgggg ugacuacccc aguguccaca      720

uauaugcuua ccaauucaga acuguugagc cucaucaacg acaugccgau uacgaacgau      780

caaaagaaac ugaugaguaa uaacguccag aucguucgcc agcagucuua cuccaucaug      840

ugcauuauaa aggaggaagu guuagcguau guagugcaac ugccccucua cggagucauc      900

gacacuccuu guuggaaacu ucauacaagc ccacugugca ccacuaauac aaaggagggc      960

ucgaacauuu guuugacccg aacggaucgu ggcugguacu gcgacaaugc agggucugug     1020

uccuucuuuc cccaggccga aaccuguaag guucagucaa acagaguguu cugcgauaca     1080

augaauagua gaacucugcc uagcgagguc aaccucugca auguggacau cuuuaaccca     1140

aaauaugauu guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu     1200

cugggagcua ucguguccug cuacgguaag acuaaaugua cagccagcaa uaagaacagg     1260

ggcaucauua agaccuucuc uaaugggugc gauuaugucu caaacaaagg aguggacacu     1320

gucagugugg gcaauacgcu uuacuguguu aacaagcaag aggguaaaag ccuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccuuugguau ucccauccga ugaguuugac     1440

gcaucuauau cgcaggucaa ugagaaaauc aaccagagcc ucgcuuucau ucggaagucc     1500

gaugaacugu uacacaaugu gaacgccgga aagucaacaa ccaauaucau gaucacuacc     1560

auuauaaucg uuauuaucgu gauucugcua agucucaucg cggucggccu gcuuuuguau     1620

ugcaaagccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5186
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5186
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucugc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc     1080

augaacagca gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaga     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacugcgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5187
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5187
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauuugu      420

uccggcgucg ccgugugcaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcgcuucugu cuaccaauaa agccgucgug ucccucagca acggaguuuc ugugcugaca      540

uuuaaggucc uugaccugaa gaauuacauu gauaaacaac uccugccuau ccugaacaag      600

caguccugua gcauuucuaa uaucgagacc gugauugagu uccagcagaa aaacaaucgg      660

cuccuggaaa ucacgcgcga guuuuccgug aacgcuggcg ucacaacccc gguuagcaca      720

uauaugcuua ccaauuccga acugcucucu cugaucaacg acaugcccau uaccaacgau      780

caaaagaaac uuaugagcaa uaacgugcag aucgugagac agcaguccua cagcauuaug      840

ugcaucauua aggaggaagu ccuggccuau gugguucaac ucccucugua cggcgugauc      900

gacacacccu guuggaaacu gcauacgucu ccucucugca ccacaaauac caaggagggg      960

uccaacaucu gucugacacg gaccgaucgc ggaugguacu gcgacaaugc uggcagcguc     1020

ucuuucuuuc cccaggccga aacguguaag gugcagagca acagaguuuu cugcgauaca     1080

augaacucca gaacccugcc uucugaggug aaucucugca augucgacau uuuuaacccg     1140

aaauaugauu guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc     1200

cugggggcga ucgugagcug cuacggaaag acaaaaugua cggccucuaa uaagaaccgg     1260

ggcauuauca agaccuucuc caaugggugc gauuauguua gcaacaaagg aguggacaca     1320

gucuccgugg gcaauacccu uuacuguguu aacaagcaag agggcaaauc ucuguaugug     1380

aagggggaac ccaucauuaa cuuuuacgac ccucucgucu uccccagcga ugaguuugac     1440

gcuuccaucu cucaggugaa ugagaaaauu aaccagagcc uggccuucau ccgcaagucc     1500

gaugaacugc uccacaaugu gaacgcugga aagagcacaa ccaauauuau gaucacgacc     1560

auuaucaucg uuauuaucgu cauucugcuu ucucugaucg ccgugggccu ccugcuguau     1620

ugcaaagcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5188
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5188
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacuaaa agcuaacgcc      120

auaaccacua uacuaacagc agucacauuc ugcuucgcau caggccaaaa cauaaccgaa      180

gaauuuuacc aauccacuug uucagcaguc uccaaaggau auuuauccgc acuucguaca      240

ggaugguaua caucaguaau aacaauagaa cucuccaaca uaaaagaaaa uaaaugcaac      300

ggcaccgacg caaaaguaaa acucaucaaa caagaauuag acaaauacaa gaacgccgua      360

acagaacuac aauuacuaau gcaaucaaca cccgccacag gaucaggauc ugcaauaugc      420

ucuggaguag caguaugcaa aguauuacac cuagaaggag aaguaaacaa aaucaaaagc      480

gcacuacuau ccacaaacaa agcuguagua ucacuaucaa acggaguauc aguauuaacu      540

uucaaaguac uugaucuaaa aaacuacaua gacaaacaac uacuacccau auuaaacaaa      600

caaucaugcu caauaagcaa uauagaaaca guaauagaau uucaacaaaa aaacaacaga      660

cuacuagaaa ucacaaggga auuuucagua aaugccggug uuacaacccc aguaucaaca      720

uacaugcuaa cuaacucaga acuacuaucc uuaauaaacg auaugccaau aacaaacgau      780

caaaaaaaac uaauguccaa caacguacaa auaguaagac aacaaucaua cucaaucaug      840

ugcauuauaa aagaagaagu cuuagcauac guaguacaau uaccacuaua cgguguaaua      900

gauacaccau guuggaaauu acacacaagc ccacuaugca caacuaacac aaaagaaggc      960

ucaaauauau guuuaacaag aacagaccga gguugguacu gcgacaaugc aggaucagua     1020

ucauucuuuc cacaagcaga aacauguaaa guucaaucca acagaguauu cugcgacaca     1080

augaacucca gaacacuacc uucagaagua aaccucugua acguagacau auuuaauccc     1140

aaguacgacu gcaaaauaau gacaucgaaa acagacguaa gcuccucagu gauaacaucc     1200

cucggcgcca ucguauccug uuacgguaaa acuaaaugua ccgccucaaa caaaaaccgc     1260

gguauuauaa aaacuuuuuc uaauggcugc gauuacguaa gcaacaaagg cgucgacaca     1320

guuuccguag gaaacacacu auacugcgua aacaaacaag aagguaaauc ucuauacgua     1380

aaaggagaac caauaauaaa uuucuaugau ccuuuaguau ucccauccga ugaauuugac     1440

gccucuaucu cacaagucaa cgaaaaaaua aaucaaucau uagcauucau acgaaaauca     1500

gacgaacuac uacacaacgu aaacgcagga aaaucaacaa ccaacauaau gauaaccaca     1560

auaauaauag uuauuauagu gauacuauua uccuuaauug cagucggacu auuauuauac     1620

uguaaagcac gcuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5189
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5189
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaaugcc      120

aucaccacaa uccugacagc aguaaccuuc ugcuucgcau ccggacaaaa caucaccgaa      180

gaauuuuacc agucaaccug cuccgcuguc ucaaaaggcu accucucagc ccuucgcacc      240

ggcugguaca ccucggucau aacaauagaa cucuccaaua ucaaagaaaa caaaugcaac      300

ggcacugacg ccaagguaaa acucaucaaa caggaacucg auaaauacaa gaacgccgua      360

acagaacuac aacuacucau gcaaucaaca ccggccaccg gcuccgguuc cgccauaugc      420

uccggagugg ccgugugcaa gguccuccac cuugaagggg aaguuaacaa aaucaaauca      480

gcccuccucu ccacuaacaa agccguagua ucccuaagca acgguguauc cguccucacc      540

uucaaaguac uagaccuaaa gaauuauauc gacaaacaac uccuccccau acucaacaaa      600

caauccugcu ccauaagcaa caucgaaaca gucaucgagu uccagcagaa aaacaaccga      660

cuccucgaaa uaacccgcga guucucaguc aacgccggag ucaccacacc cgucagcacc      720

uacaugcuga ccaacuccga acuccucucc uuaaucaaug acaugcccau caccaaugac      780

caaaagaaac ucaugucaaa caacguccaa auaguacgcc aacaauccua cuccaucaug      840

ugcaucauaa aagaagaagu acucgccuac gucguccaac ucccccucua cggcguaauc      900

gacacccccu gcuggaaacu acacacaagc ccccucugca ccacaaacac uaaagagggc      960

uccaacaucu gucuaacccg caccgaucga ggcugguacu gcgacaacgc cggaucuguc     1020

ucauucuucc cccaagccga aaccugcaaa guccaaucca accgcgucuu cugcgacacc     1080

augaacucga gaacccuccc uuccgaaguc aaccuaugca acgucgacau uuucaacccc     1140

aaauacgacu gcaaaaucau gaccucgaaa accgacguau cauccagcgu caucaccagc     1200

cuaggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgcgagcaa uaaaaaccgc     1260

gggaucauca aaacuuucuc caacggcugc gacuacgucu ccaacaaggg agucgauacc     1320

gucuccguag gcaacacccu cuacugcguc aacaaacaag aaggcaaauc acuauacgua     1380

aaaggcgagc caaucauaaa cuucuacgac ccucuaguuu ucccauccga cgaguucgac     1440

gcuagcaucu cccaagucaa cgagaaaauc aaccaauccc ucgcauucau ccgcaaaucc     1500

gacgaacucc uccacaacgu aaacgcaggc aaaucaacua cuaauauaau gaucacaacc     1560

aucauaauag ucauaaucgu aauccuccua ucccucaucg ccgucggacu acugcucuac     1620

ugcaaagccc gcuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5190
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5190
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5191
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5191
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5192
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5192
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5193
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5193
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5194
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5194
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5195
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5195
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5196
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5196
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacuaaaagc uaacgccaua accacuauac      120

uaacagcagu cacauucugc uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau      180

ccacuuguuc agcagucucc aaaggauauu uauccgcacu ucguacagga ugguauacau      240

caguaauaac aauagaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcaa      300

aaguaaaacu caucaaacaa gaauuagaca aauacaagaa cgccguaaca gaacuacaau      360

uacuaaugca aucaacaccc gccacaggau caggaucugc aauaugcucu ggaguagcag      420

uaugcaaagu auuacaccua gaaggagaag uaaacaaaau caaaagcgca cuacuaucca      480

caaacaaagc uguaguauca cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug      540

aucuaaaaaa cuacauagac aaacaacuac uacccauauu aaacaaacaa ucaugcucaa      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua cuagaaauca      660

caagggaauu uucaguaaau gccgguguua caaccccagu aucaacauac augcuaacua      720

acucagaacu acuauccuua auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauacuc aaucaugugc auuauaaaag      840

aagaagucuu agcauacgua guacaauuac cacuauacgg uguaauagau acaccauguu      900

ggaaauuaca cacaagccca cuaugcacaa cuaacacaaa agaaggcuca aauauauguu      960

uaacaagaac agaccgaggu ugguacugcg acaaugcagg aucaguauca uucuuuccac     1020

aagcagaaac auguaaaguu caauccaaca gaguauucug cgacacaaug aacuccagaa     1080

cacuaccuuc agaaguaaac cucuguaacg uagacauauu uaaucccaag uacgacugca     1140

aaauaaugac aucgaaaaca gacguaagcu ccucagugau aacaucccuc ggcgccaucg     1200

uauccuguua cgguaaaacu aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa     1260

cuuuuucuaa uggcugcgau uacguaagca acaaaggcgu cgacacaguu uccguaggaa     1320

acacacuaua cugcguaaac aaacaagaag guaaaucucu auacguaaaa ggagaaccaa     1380

uaauaaauuu cuaugauccu uuaguauucc cauccgauga auuugacgcc ucuaucucac     1440

aagucaacga aaaaauaaau caaucauuag cauucauacg aaaaucagac gaacuacuac     1500

acaacguaaa cgcaggaaaa ucaacaacca acauaaugau aaccacaaua auaauaguua     1560

uuauagugau acuauuaucc uuaauugcag ucggacuauu auuauacugu aaagcacgcu     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5197
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5197
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caaugccauc accacaaucc      120

ugacagcagu aaccuucugc uucgcauccg gacaaaacau caccgaagaa uuuuaccagu      180

caaccugcuc cgcugucuca aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaauauca aagaaaacaa augcaacggc acugacgcca      300

agguaaaacu caucaaacag gaacucgaua aauacaagaa cgccguaaca gaacuacaac      360

uacucaugca aucaacaccg gccaccggcu ccgguuccgc cauaugcucc ggaguggccg      420

ugugcaaggu ccuccaccuu gaaggggaag uuaacaaaau caaaucagcc cuccucucca      480

cuaacaaagc cguaguaucc cuaagcaacg guguauccgu ccucaccuuc aaaguacuag      540

accuaaagaa uuauaucgac aaacaacucc uccccauacu caacaaacaa uccugcucca      600

uaagcaacau cgaaacaguc aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa      660

cccgcgaguu cucagucaac gccggaguca ccacacccgu cagcaccuac augcugacca      720

acuccgaacu ccucuccuua aucaaugaca ugcccaucac caaugaccaa aagaaacuca      780

ugucaaacaa cguccaaaua guacgccaac aauccuacuc caucaugugc aucauaaaag      840

aagaaguacu cgccuacguc guccaacucc cccucuacgg cguaaucgac acccccugcu      900

ggaaacuaca cacaagcccc cucugcacca caaacacuaa agagggcucc aacaucuguc      960

uaacccgcac cgaucgaggc ugguacugcg acaacgccgg aucugucuca uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucgagaa     1080

cccucccuuc cgaagucaac cuaugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cucgaaaacc gacguaucau ccagcgucau caccagccua ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa     1260

cuuucuccaa cggcugcgac uacgucucca acaagggagu cgauaccguc uccguaggca     1320

acacccucua cugcgucaac aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa     1380

ucauaaacuu cuacgacccu cuaguuuucc cauccgacga guucgacgcu agcaucuccc     1440

aagucaacga gaaaaucaac caaucccucg cauucauccg caaauccgac gaacuccucc     1500

acaacguaaa cgcaggcaaa ucaacuacua auauaaugau cacaaccauc auaauaguca     1560

uaaucguaau ccuccuaucc cucaucgccg ucggacuacu gcucuacugc aaagcccgcu     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5198
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5198
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug aucgaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug cagagcaacc gcguguucug cgacaccaug aacucccgga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaaccggggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5199
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5199
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucugcagc ggcguggccg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcg cugcugagca      480

ccaacaaggc cguggucucc cucagcaacg ggguguccgu gcugacguuc aagguccugg      540

accucaagaa cuacaucgac aagcagcugc ugccgauccu caacaagcag agcugcucca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caaccggcug cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcucacca      720

acagcgagcu gcugucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcucc cccuguacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cucugcacca ccaacacgaa ggagggcucc aacaucugcc      960

ugacccgcac cgaccggggg ugguacugcg acaacgccgg cuccgugagc uucuuccccc     1020

aggcggagac cugcaagguc caguccaacc gcguguucug cgacacgaug aacagccgga     1080

cccuccccuc cgaggucaac cugugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaaccggggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccucua cugcgucaac aagcaggagg ggaagucccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caagagcgac gagcugcugc     1500

acaacgugaa cgcggggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccuccugagc cugaucgccg ugggccuccu gcuguacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5200
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5200
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucugcucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc aucgaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc caguccaacc gcgucuucug cgacaccaug aacucccgca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cugcgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5201
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5201
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauauguagc ggaguggcag      420

ucugcaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcc cugcugucca      480

cgaauaaagc uguggucucu cucagcaacg guguguccgu auuaacuuuu aagguucugg      540

accuuaagaa uuacauugau aaacaauugc ugccuauccu aaacaagcag ucauguagua      600

uuagcaauau cgagaccgug auagaguucc agcagaaaaa caauaggcuc cuggaaauua      660

cacgggaguu uucugucaac gccgggguga cuaccccagu guccacauau augcuuacca      720

auucagaacu guugagccuc aucaacgaca ugccgauuac gaacgaucaa aagaaacuga      780

ugaguaauaa cguccagauc guucgccagc agucuuacuc caucaugugc auuauaaagg      840

aggaaguguu agcguaugua gugcaacugc cccucuacgg agucaucgac acuccuuguu      900

ggaaacuuca uacaagccca cugugcacca cuaauacaaa ggagggcucg aacauuuguu      960

ugacccgaac ggaucguggc ugguacugcg acaaugcagg gucugugucc uucuuucccc     1020

aggccgaaac cuguaagguu cagucaaaca gaguguucug cgauacaaug aauaguagaa     1080

cucugccuag cgaggucaac cucugcaaug uggacaucuu uaacccaaaa uaugauugua     1140

agauaaugac cuccaaaaca gacguaucua gcucaguuau uaccagucug ggagcuaucg     1200

uguccugcua cgguaagacu aaauguacag ccagcaauaa gaacaggggc aucauuaaga     1260

ccuucucuaa ugggugcgau uaugucucaa acaaaggagu ggacacuguc agugugggca     1320

auacgcuuua cuguguuaac aagcaagagg guaaaagccu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu uugguauucc cauccgauga guuugacgca ucuauaucgc     1440

aggucaauga gaaaaucaac cagagccucg cuuucauucg gaaguccgau gaacuguuac     1500

acaaugugaa cgccggaaag ucaacaacca auaucaugau cacuaccauu auaaucguua     1560

uuaucgugau ucugcuaagu cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5202
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5202
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucugcagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug aucgaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug cagagcaaca gaguguucug cgacaccaug aacagcagaa     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacagaggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cugcgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5203
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5203
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauuuguucc ggcgucgccg      420

ugugcaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcg cuucugucua      480

ccaauaaagc cgucgugucc cucagcaacg gaguuucugu gcugacauuu aagguccuug      540

accugaagaa uuacauugau aaacaacucc ugccuauccu gaacaagcag uccuguagca      600

uuucuaauau cgagaccgug auugaguucc agcagaaaaa caaucggcuc cuggaaauca      660

cgcgcgaguu uuccgugaac gcuggcguca caaccccggu uagcacauau augcuuacca      720

auuccgaacu gcucucucug aucaacgaca ugcccauuac caacgaucaa aagaaacuua      780

ugagcaauaa cgugcagauc gugagacagc aguccuacag cauuaugugc aucauuaagg      840

aggaaguccu ggccuaugug guucaacucc cucuguacgg cgugaucgac acacccuguu      900

ggaaacugca uacgucuccu cucugcacca caaauaccaa ggaggggucc aacaucuguc      960

ugacacggac cgaucgcgga ugguacugcg acaaugcugg cagcgucucu uucuuucccc     1020

aggccgaaac guguaaggug cagagcaaca gaguuuucug cgauacaaug aacuccagaa     1080

cccugccuuc ugaggugaau cucugcaaug ucgacauuuu uaacccgaaa uaugauugua     1140

agaucaugac cagcaaaaca gacgugucca gcucugucau uaccucccug ggggcgaucg     1200

ugagcugcua cggaaagaca aaauguacgg ccucuaauaa gaaccggggc auuaucaaga     1260

ccuucuccaa ugggugcgau uauguuagca acaaaggagu ggacacaguc uccgugggca     1320

auacccuuua cuguguuaac aagcaagagg gcaaaucucu guaugugaag ggggaaccca     1380

ucauuaacuu uuacgacccu cucgucuucc ccagcgauga guuugacgcu uccaucucuc     1440

aggugaauga gaaaauuaac cagagccugg ccuucauccg caaguccgau gaacugcucc     1500

acaaugugaa cgcuggaaag agcacaacca auauuaugau cacgaccauu aucaucguua     1560

uuaucgucau ucugcuuucu cugaucgccg ugggccuccu gcuguauugc aaagccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5204
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5204
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacuaaaagc uaacgccaua accacuauac      120

uaacagcagu cacauucugc uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau      180

ccacuuguuc agcagucucc aaaggauauu uauccgcacu ucguacagga ugguauacau      240

caguaauaac aauagaacuc uccaacauaa aagaaaauaa augcaacggc accgacgcaa      300

aaguaaaacu caucaaacaa gaauuagaca aauacaagaa cgccguaaca gaacuacaau      360

uacuaaugca aucaacaccc gccacaggau caggaucugc aauaugcucu ggaguagcag      420

uaugcaaagu auuacaccua gaaggagaag uaaacaaaau caaaagcgca cuacuaucca      480

caaacaaagc uguaguauca cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug      540

aucuaaaaaa cuacauagac aaacaacuac uacccauauu aaacaaacaa ucaugcucaa      600

uaagcaauau agaaacagua auagaauuuc aacaaaaaaa caacagacua cuagaaauca      660

caagggaauu uucaguaaau gccgguguua caaccccagu aucaacauac augcuaacua      720

acucagaacu acuauccuua auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauacuc aaucaugugc auuauaaaag      840

aagaagucuu agcauacgua guacaauuac cacuauacgg uguaauagau acaccauguu      900

ggaaauuaca cacaagccca cuaugcacaa cuaacacaaa agaaggcuca aauauauguu      960

uaacaagaac agaccgaggu ugguacugcg acaaugcagg aucaguauca uucuuuccac     1020

aagcagaaac auguaaaguu caauccaaca gaguauucug cgacacaaug aacuccagaa     1080

cacuaccuuc agaaguaaac cucuguaacg uagacauauu uaaucccaag uacgacugca     1140

aaauaaugac aucgaaaaca gacguaagcu ccucagugau aacaucccuc ggcgccaucg     1200

uauccuguua cgguaaaacu aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa     1260

cuuuuucuaa uggcugcgau uacguaagca acaaaggcgu cgacacaguu uccguaggaa     1320

acacacuaua cugcguaaac aaacaagaag guaaaucucu auacguaaaa ggagaaccaa     1380

uaauaaauuu cuaugauccu uuaguauucc cauccgauga auuugacgcc ucuaucucac     1440

aagucaacga aaaaauaaau caaucauuag cauucauacg aaaaucagac gaacuacuac     1500

acaacguaaa cgcaggaaaa ucaacaacca acauaaugau aaccacaaua auaauaguua     1560

uuauagugau acuauuaucc uuaauugcag ucggacuauu auuauacugu aaagcacgcu     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5205
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5205
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caaugccauc accacaaucc      120

ugacagcagu aaccuucugc uucgcauccg gacaaaacau caccgaagaa uuuuaccagu      180

caaccugcuc cgcugucuca aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu      240

cggucauaac aauagaacuc uccaauauca aagaaaacaa augcaacggc acugacgcca      300

agguaaaacu caucaaacag gaacucgaua aauacaagaa cgccguaaca gaacuacaac      360

uacucaugca aucaacaccg gccaccggcu ccgguuccgc cauaugcucc ggaguggccg      420

ugugcaaggu ccuccaccuu gaaggggaag uuaacaaaau caaaucagcc cuccucucca      480

cuaacaaagc cguaguaucc cuaagcaacg guguauccgu ccucaccuuc aaaguacuag      540

accuaaagaa uuauaucgac aaacaacucc uccccauacu caacaaacaa uccugcucca      600

uaagcaacau cgaaacaguc aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa      660

cccgcgaguu cucagucaac gccggaguca ccacacccgu cagcaccuac augcugacca      720

acuccgaacu ccucuccuua aucaaugaca ugcccaucac caaugaccaa aagaaacuca      780

ugucaaacaa cguccaaaua guacgccaac aauccuacuc caucaugugc aucauaaaag      840

aagaaguacu cgccuacguc guccaacucc cccucuacgg cguaaucgac acccccugcu      900

ggaaacuaca cacaagcccc cucugcacca caaacacuaa agagggcucc aacaucuguc      960

uaacccgcac cgaucgaggc ugguacugcg acaacgccgg aucugucuca uucuuccccc     1020

aagccgaaac cugcaaaguc caauccaacc gcgucuucug cgacaccaug aacucgagaa     1080

cccucccuuc cgaagucaac cuaugcaacg ucgacauuuu caaccccaaa uacgacugca     1140

aaaucaugac cucgaaaacc gacguaucau ccagcgucau caccagccua ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa     1260

cuuucuccaa cggcugcgac uacgucucca acaagggagu cgauaccguc uccguaggca     1320

acacccucua cugcgucaac aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa     1380

ucauaaacuu cuacgacccu cuaguuuucc cauccgacga guucgacgcu agcaucuccc     1440

aagucaacga gaaaaucaac caaucccucg cauucauccg caaauccgac gaacuccucc     1500

acaacguaaa cgcaggcaaa ucaacuacua auauaaugau cacaaccauc auaauaguca     1560

uaaucguaau ccuccuaucc cucaucgccg ucggacuacu gcucuacugc aaagcccgcu     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  5206
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5206
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5207
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5207
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5208
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5208
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5209
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5209
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5210
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5210
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5211
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5211
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5212
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5212
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacuaaaa gcuaacgcca uaaccacuau acuaacagca      120

gucacauucu gcuucgcauc aggccaaaac auaaccgaag aauuuuacca auccacuugu      180

ucagcagucu ccaaaggaua uuuauccgca cuucguacag gaugguauac aucaguaaua      240

acaauagaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc aaaaguaaaa      300

cucaucaaac aagaauuaga caaauacaag aacgccguaa cagaacuaca auuacuaaug      360

caaucaacac ccgccacagg aucaggaucu gcaauaugcu cuggaguagc aguaugcaaa      420

guauuacacc uagaaggaga aguaaacaaa aucaaaagcg cacuacuauc cacaaacaaa      480

gcuguaguau cacuaucaaa cggaguauca guauuaacuu ucaaaguacu ugaucuaaaa      540

aacuacauag acaaacaacu acuacccaua uuaaacaaac aaucaugcuc aauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uacuagaaau cacaagggaa      660

uuuucaguaa augccggugu uacaacccca guaucaacau acaugcuaac uaacucagaa      720

cuacuauccu uaauaaacga uaugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uaguaagaca acaaucauac ucaaucaugu gcauuauaaa agaagaaguc      840

uuagcauacg uaguacaauu accacuauac gguguaauag auacaccaug uuggaaauua      900

cacacaagcc cacuaugcac aacuaacaca aaagaaggcu caaauauaug uuuaacaaga      960

acagaccgag guugguacug cgacaaugca ggaucaguau cauucuuucc acaagcagaa     1020

acauguaaag uucaauccaa cagaguauuc ugcgacacaa ugaacuccag aacacuaccu     1080

ucagaaguaa accucuguaa cguagacaua uuuaauccca aguacgacug caaaauaaug     1140

acaucgaaaa cagacguaag cuccucagug auaacauccc ucggcgccau cguauccugu     1200

uacgguaaaa cuaaauguac cgccucaaac aaaaaccgcg guauuauaaa aacuuuuucu     1260

aauggcugcg auuacguaag caacaaaggc gucgacacag uuuccguagg aaacacacua     1320

uacugcguaa acaaacaaga agguaaaucu cuauacguaa aaggagaacc aauaauaaau     1380

uucuaugauc cuuuaguauu cccauccgau gaauuugacg ccucuaucuc acaagucaac     1440

gaaaaaauaa aucaaucauu agcauucaua cgaaaaucag acgaacuacu acacaacgua     1500

aacgcaggaa aaucaacaac caacauaaug auaaccacaa uaauaauagu uauuauagug     1560

auacuauuau ccuuaauugc agucggacua uuauuauacu guaaagcacg cuaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5213
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5213
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaaugcca ucaccacaau ccugacagca      120

guaaccuucu gcuucgcauc cggacaaaac aucaccgaag aauuuuacca gucaaccugc      180

uccgcugucu caaaaggcua ccucucagcc cuucgcaccg gcugguacac cucggucaua      240

acaauagaac ucuccaauau caaagaaaac aaaugcaacg gcacugacgc caagguaaaa      300

cucaucaaac aggaacucga uaaauacaag aacgccguaa cagaacuaca acuacucaug      360

caaucaacac cggccaccgg cuccgguucc gccauaugcu ccggaguggc cgugugcaag      420

guccuccacc uugaagggga aguuaacaaa aucaaaucag cccuccucuc cacuaacaaa      480

gccguaguau cccuaagcaa cgguguaucc guccucaccu ucaaaguacu agaccuaaag      540

aauuauaucg acaaacaacu ccuccccaua cucaacaaac aauccugcuc cauaagcaac      600

aucgaaacag ucaucgaguu ccagcagaaa aacaaccgac uccucgaaau aacccgcgag      660

uucucaguca acgccggagu caccacaccc gucagcaccu acaugcugac caacuccgaa      720

cuccucuccu uaaucaauga caugcccauc accaaugacc aaaagaaacu caugucaaac      780

aacguccaaa uaguacgcca acaauccuac uccaucaugu gcaucauaaa agaagaagua      840

cucgccuacg ucguccaacu cccccucuac ggcguaaucg acacccccug cuggaaacua      900

cacacaagcc cccucugcac cacaaacacu aaagagggcu ccaacaucug ucuaacccgc      960

accgaucgag gcugguacug cgacaacgcc ggaucugucu cauucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucgag aacccucccu     1080

uccgaaguca accuaugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accucgaaaa ccgacguauc auccagcguc aucaccagcc uaggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgcgagcaau aaaaaccgcg ggaucaucaa aacuuucucc     1260

aacggcugcg acuacgucuc caacaaggga gucgauaccg ucuccguagg caacacccuc     1320

uacugcguca acaaacaaga aggcaaauca cuauacguaa aaggcgagcc aaucauaaac     1380

uucuacgacc cucuaguuuu cccauccgac gaguucgacg cuagcaucuc ccaagucaac     1440

gagaaaauca accaaucccu cgcauucauc cgcaaauccg acgaacuccu ccacaacgua     1500

aacgcaggca aaucaacuac uaauauaaug aucacaacca ucauaauagu cauaaucgua     1560

auccuccuau cccucaucgc cgucggacua cugcucuacu gcaaagcccg cuaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  5214
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5214
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucugca gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugaucgaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugcagagcaa ccgcguguuc ugcgacacca ugaacucccg gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaaccggg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacugcguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5215
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5215
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucugca gcggcguggc cgugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cgcugcugag caccaacaag      480

gccguggucu cccucagcaa cggggugucc gugcugacgu ucaagguccu ggaccucaag      540

aacuacaucg acaagcagcu gcugccgauc cucaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaaccggc ugcuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcucac caacagcgag      720

cugcuguccc ucaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu cccccuguac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccucugcac caccaacacg aaggagggcu ccaacaucug ccugacccgc      960

accgaccggg ggugguacug cgacaacgcc ggcuccguga gcuucuuccc ccaggcggag     1020

accugcaagg uccaguccaa ccgcguguuc ugcgacacga ugaacagccg gacccucccc     1080

uccgagguca accugugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaaccggg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccuc     1320

uacugcguca acaagcagga ggggaagucc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaagagcg acgagcugcu gcacaacgug     1500

aacgcgggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccuccuga gccugaucgc cgugggccuc cugcuguacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5216
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5216
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucugcu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucaucgaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg uccaguccaa ccgcgucuuc ugcgacacca ugaacucccg cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaaccgcg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacugcguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5217
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5217
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauaugua gcggaguggc agucugcaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cccugcuguc cacgaauaaa      480

gcuguggucu cucucagcaa cggugugucc guauuaacuu uuaagguucu ggaccuuaag      540

aauuacauug auaaacaauu gcugccuauc cuaaacaagc agucauguag uauuagcaau      600

aucgagaccg ugauagaguu ccagcagaaa aacaauaggc uccuggaaau uacacgggag      660

uuuucuguca acgccggggu gacuacccca guguccacau auaugcuuac caauucagaa      720

cuguugagcc ucaucaacga caugccgauu acgaacgauc aaaagaaacu gaugaguaau      780

aacguccaga ucguucgcca gcagucuuac uccaucaugu gcauuauaaa ggaggaagug      840

uuagcguaug uagugcaacu gccccucuac ggagucaucg acacuccuug uuggaaacuu      900

cauacaagcc cacugugcac cacuaauaca aaggagggcu cgaacauuug uuugacccga      960

acggaucgug gcugguacug cgacaaugca gggucugugu ccuucuuucc ccaggccgaa     1020

accuguaagg uucagucaaa cagaguguuc ugcgauacaa ugaauaguag aacucugccu     1080

agcgagguca accucugcaa uguggacauc uuuaacccaa aauaugauug uaagauaaug     1140

accuccaaaa cagacguauc uagcucaguu auuaccaguc ugggagcuau cguguccugc     1200

uacgguaaga cuaaauguac agccagcaau aagaacaggg gcaucauuaa gaccuucucu     1260

aaugggugcg auuaugucuc aaacaaagga guggacacug ucaguguggg caauacgcuu     1320

uacuguguua acaagcaaga ggguaaaagc cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cuuugguauu cccauccgau gaguuugacg caucuauauc gcaggucaau     1440

gagaaaauca accagagccu cgcuuucauu cggaaguccg augaacuguu acacaaugug     1500

aacgccggaa agucaacaac caauaucaug aucacuacca uuauaaucgu uauuaucgug     1560

auucugcuaa gucucaucgc ggucggccug cuuuuguauu gcaaagcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5218
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5218
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucugca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugaucgaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugcagagcaa cagaguguuc ugcgacacca ugaacagcag aacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacagag gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacugcguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5219
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5219
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauuuguu ccggcgucgc cgugugcaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cgcuucuguc uaccaauaaa      480

gccgucgugu cccucagcaa cggaguuucu gugcugacau uuaagguccu ugaccugaag      540

aauuacauug auaaacaacu ccugccuauc cugaacaagc aguccuguag cauuucuaau      600

aucgagaccg ugauugaguu ccagcagaaa aacaaucggc uccuggaaau cacgcgcgag      660

uuuuccguga acgcuggcgu cacaaccccg guuagcacau auaugcuuac caauuccgaa      720

cugcucucuc ugaucaacga caugcccauu accaacgauc aaaagaaacu uaugagcaau      780

aacgugcaga ucgugagaca gcaguccuac agcauuaugu gcaucauuaa ggaggaaguc      840

cuggccuaug ugguucaacu cccucuguac ggcgugaucg acacacccug uuggaaacug      900

cauacgucuc cucucugcac cacaaauacc aaggaggggu ccaacaucug ucugacacgg      960

accgaucgcg gaugguacug cgacaaugcu ggcagcgucu cuuucuuucc ccaggccgaa     1020

acguguaagg ugcagagcaa cagaguuuuc ugcgauacaa ugaacuccag aacccugccu     1080

ucugagguga aucucugcaa ugucgacauu uuuaacccga aauaugauug uaagaucaug     1140

accagcaaaa cagacguguc cagcucuguc auuaccuccc ugggggcgau cgugagcugc     1200

uacggaaaga caaaauguac ggccucuaau aagaaccggg gcauuaucaa gaccuucucc     1260

aaugggugcg auuauguuag caacaaagga guggacacag ucuccguggg caauacccuu     1320

uacuguguua acaagcaaga gggcaaaucu cuguauguga agggggaacc caucauuaac     1380

uuuuacgacc cucucgucuu ccccagcgau gaguuugacg cuuccaucuc ucaggugaau     1440

gagaaaauua accagagccu ggccuucauc cgcaaguccg augaacugcu ccacaaugug     1500

aacgcuggaa agagcacaac caauauuaug aucacgacca uuaucaucgu uauuaucguc     1560

auucugcuuu cucugaucgc cgugggccuc cugcuguauu gcaaagccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5220
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5220
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacuaaaa gcuaacgcca uaaccacuau acuaacagca      120

gucacauucu gcuucgcauc aggccaaaac auaaccgaag aauuuuacca auccacuugu      180

ucagcagucu ccaaaggaua uuuauccgca cuucguacag gaugguauac aucaguaaua      240

acaauagaac ucuccaacau aaaagaaaau aaaugcaacg gcaccgacgc aaaaguaaaa      300

cucaucaaac aagaauuaga caaauacaag aacgccguaa cagaacuaca auuacuaaug      360

caaucaacac ccgccacagg aucaggaucu gcaauaugcu cuggaguagc aguaugcaaa      420

guauuacacc uagaaggaga aguaaacaaa aucaaaagcg cacuacuauc cacaaacaaa      480

gcuguaguau cacuaucaaa cggaguauca guauuaacuu ucaaaguacu ugaucuaaaa      540

aacuacauag acaaacaacu acuacccaua uuaaacaaac aaucaugcuc aauaagcaau      600

auagaaacag uaauagaauu ucaacaaaaa aacaacagac uacuagaaau cacaagggaa      660

uuuucaguaa augccggugu uacaacccca guaucaacau acaugcuaac uaacucagaa      720

cuacuauccu uaauaaacga uaugccaaua acaaacgauc aaaaaaaacu aauguccaac      780

aacguacaaa uaguaagaca acaaucauac ucaaucaugu gcauuauaaa agaagaaguc      840

uuagcauacg uaguacaauu accacuauac gguguaauag auacaccaug uuggaaauua      900

cacacaagcc cacuaugcac aacuaacaca aaagaaggcu caaauauaug uuuaacaaga      960

acagaccgag guugguacug cgacaaugca ggaucaguau cauucuuucc acaagcagaa     1020

acauguaaag uucaauccaa cagaguauuc ugcgacacaa ugaacuccag aacacuaccu     1080

ucagaaguaa accucuguaa cguagacaua uuuaauccca aguacgacug caaaauaaug     1140

acaucgaaaa cagacguaag cuccucagug auaacauccc ucggcgccau cguauccugu     1200

uacgguaaaa cuaaauguac cgccucaaac aaaaaccgcg guauuauaaa aacuuuuucu     1260

aauggcugcg auuacguaag caacaaaggc gucgacacag uuuccguagg aaacacacua     1320

uacugcguaa acaaacaaga agguaaaucu cuauacguaa aaggagaacc aauaauaaau     1380

uucuaugauc cuuuaguauu cccauccgau gaauuugacg ccucuaucuc acaagucaac     1440

gaaaaaauaa aucaaucauu agcauucaua cgaaaaucag acgaacuacu acacaacgua     1500

aacgcaggaa aaucaacaac caacauaaug auaaccacaa uaauaauagu uauuauagug     1560

auacuauuau ccuuaauugc agucggacua uuauuauacu guaaagcacg cuaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5221
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5221
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaaugcca ucaccacaau ccugacagca      120

guaaccuucu gcuucgcauc cggacaaaac aucaccgaag aauuuuacca gucaaccugc      180

uccgcugucu caaaaggcua ccucucagcc cuucgcaccg gcugguacac cucggucaua      240

acaauagaac ucuccaauau caaagaaaac aaaugcaacg gcacugacgc caagguaaaa      300

cucaucaaac aggaacucga uaaauacaag aacgccguaa cagaacuaca acuacucaug      360

caaucaacac cggccaccgg cuccgguucc gccauaugcu ccggaguggc cgugugcaag      420

guccuccacc uugaagggga aguuaacaaa aucaaaucag cccuccucuc cacuaacaaa      480

gccguaguau cccuaagcaa cgguguaucc guccucaccu ucaaaguacu agaccuaaag      540

aauuauaucg acaaacaacu ccuccccaua cucaacaaac aauccugcuc cauaagcaac      600

aucgaaacag ucaucgaguu ccagcagaaa aacaaccgac uccucgaaau aacccgcgag      660

uucucaguca acgccggagu caccacaccc gucagcaccu acaugcugac caacuccgaa      720

cuccucuccu uaaucaauga caugcccauc accaaugacc aaaagaaacu caugucaaac      780

aacguccaaa uaguacgcca acaauccuac uccaucaugu gcaucauaaa agaagaagua      840

cucgccuacg ucguccaacu cccccucuac ggcguaaucg acacccccug cuggaaacua      900

cacacaagcc cccucugcac cacaaacacu aaagagggcu ccaacaucug ucuaacccgc      960

accgaucgag gcugguacug cgacaacgcc ggaucugucu cauucuuccc ccaagccgaa     1020

accugcaaag uccaauccaa ccgcgucuuc ugcgacacca ugaacucgag aacccucccu     1080

uccgaaguca accuaugcaa cgucgacauu uucaacccca aauacgacug caaaaucaug     1140

accucgaaaa ccgacguauc auccagcguc aucaccagcc uaggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgcgagcaau aaaaaccgcg ggaucaucaa aacuuucucc     1260

aacggcugcg acuacgucuc caacaaggga gucgauaccg ucuccguagg caacacccuc     1320

uacugcguca acaaacaaga aggcaaauca cuauacguaa aaggcgagcc aaucauaaac     1380

uucuacgacc cucuaguuuu cccauccgac gaguucgacg cuagcaucuc ccaagucaac     1440

gagaaaauca accaaucccu cgcauucauc cgcaaauccg acgaacuccu ccacaacgua     1500

aacgcaggca aaucaacuac uaauauaaug aucacaacca ucauaauagu cauaaucgua     1560

auccuccuau cccucaucgc cgucggacua cugcucuacu gcaaagcccg cuaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  5222
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5222
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5223
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5223
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5224
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5224
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5225
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5225
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5226
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5226
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5227
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5227
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5228
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5228
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acuaaaagcu      120

aacgccauaa ccacuauacu aacagcaguc acauucugcu ucgcaucagg ccaaaacaua      180

accgaagaau uuuaccaauc cacuuguuca gcagucucca aaggauauuu auccgcacuu      240

cguacaggau gguauacauc aguaauaaca auagaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgcaaa aguaaaacuc aucaaacaag aauuagacaa auacaagaac      360

gccguaacag aacuacaauu acuaaugcaa ucaacacccg ccacaggauc aggaucugca      420

auaugcucug gaguagcagu augcaaagua uuacaccuag aaggagaagu aaacaaaauc      480

aaaagcgcac uacuauccac aaacaaagcu guaguaucac uaucaaacgg aguaucagua      540

uuaacuuuca aaguacuuga ucuaaaaaac uacauagaca aacaacuacu acccauauua      600

aacaaacaau caugcucaau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuac uagaaaucac aagggaauuu ucaguaaaug ccgguguuac aaccccagua      720

ucaacauaca ugcuaacuaa cucagaacua cuauccuuaa uaaacgauau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag uaagacaaca aucauacuca      840

aucaugugca uuauaaaaga agaagucuua gcauacguag uacaauuacc acuauacggu      900

guaauagaua caccauguug gaaauuacac acaagcccac uaugcacaac uaacacaaaa      960

gaaggcucaa auauauguuu aacaagaaca gaccgagguu gguacugcga caaugcagga     1020

ucaguaucau ucuuuccaca agcagaaaca uguaaaguuc aauccaacag aguauucugc     1080

gacacaauga acuccagaac acuaccuuca gaaguaaacc ucuguaacgu agacauauuu     1140

aaucccaagu acgacugcaa aauaaugaca ucgaaaacag acguaagcuc cucagugaua     1200

acaucccucg gcgccaucgu auccuguuac gguaaaacua aauguaccgc cucaaacaaa     1260

aaccgcggua uuauaaaaac uuuuucuaau ggcugcgauu acguaagcaa caaaggcguc     1320

gacacaguuu ccguaggaaa cacacuauac ugcguaaaca aacaagaagg uaaaucucua     1380

uacguaaaag gagaaccaau aauaaauuuc uaugauccuu uaguauuccc auccgaugaa     1440

uuugacgccu cuaucucaca agucaacgaa aaaauaaauc aaucauuagc auucauacga     1500

aaaucagacg aacuacuaca caacguaaac gcaggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaauaguuau uauagugaua cuauuauccu uaauugcagu cggacuauua     1620

uuauacugua aagcacgcua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5229
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5229
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aaugccauca ccacaauccu gacagcagua accuucugcu ucgcauccgg acaaaacauc      180

accgaagaau uuuaccaguc aaccugcucc gcugucucaa aaggcuaccu cucagcccuu      240

cgcaccggcu gguacaccuc ggucauaaca auagaacucu ccaauaucaa agaaaacaaa      300

ugcaacggca cugacgccaa gguaaaacuc aucaaacagg aacucgauaa auacaagaac      360

gccguaacag aacuacaacu acucaugcaa ucaacaccgg ccaccggcuc cgguuccgcc      420

auaugcuccg gaguggccgu gugcaagguc cuccaccuug aaggggaagu uaacaaaauc      480

aaaucagccc uccucuccac uaacaaagcc guaguauccc uaagcaacgg uguauccguc      540

cucaccuuca aaguacuaga ccuaaagaau uauaucgaca aacaacuccu ccccauacuc      600

aacaaacaau ccugcuccau aagcaacauc gaaacaguca ucgaguucca gcagaaaaac      660

aaccgacucc ucgaaauaac ccgcgaguuc ucagucaacg ccggagucac cacacccguc      720

agcaccuaca ugcugaccaa cuccgaacuc cucuccuuaa ucaaugacau gcccaucacc      780

aaugaccaaa agaaacucau gucaaacaac guccaaauag uacgccaaca auccuacucc      840

aucaugugca ucauaaaaga agaaguacuc gccuacgucg uccaacuccc ccucuacggc      900

guaaucgaca cccccugcug gaaacuacac acaagccccc ucugcaccac aaacacuaaa      960

gagggcucca acaucugucu aacccgcacc gaucgaggcu gguacugcga caacgccgga     1020

ucugucucau ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucgagaac ccucccuucc gaagucaacc uaugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucgaaaaccg acguaucauc cagcgucauc     1200

accagccuag gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc gagcaauaaa     1260

aaccgcggga ucaucaaaac uuucuccaac ggcugcgacu acgucuccaa caagggaguc     1320

gauaccgucu ccguaggcaa cacccucuac ugcgucaaca aacaagaagg caaaucacua     1380

uacguaaaag gcgagccaau cauaaacuuc uacgacccuc uaguuuuccc auccgacgag     1440

uucgacgcua gcaucuccca agucaacgag aaaaucaacc aaucccucgc auucauccgc     1500

aaauccgacg aacuccucca caacguaaac gcaggcaaau caacuacuaa uauaaugauc     1560

acaaccauca uaauagucau aaucguaauc cuccuauccc ucaucgccgu cggacuacug     1620

cucuacugca aagcccgcua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5230
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5230
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucugcagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga ucgaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugc agagcaaccg cguguucugc     1080

gacaccauga acucccggac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aaccggggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac ugcgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5231
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5231
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucugcagcg gcguggccgu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgcgc ugcugagcac caacaaggcc guggucuccc ucagcaacgg gguguccgug      540

cugacguuca agguccugga ccucaagaac uacaucgaca agcagcugcu gccgauccuc      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aaccggcugc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcucaccaa cagcgagcug cugucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcuccc ccuguacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ucugcaccac caacacgaag      960

gagggcucca acaucugccu gacccgcacc gaccgggggu gguacugcga caacgccggc     1020

uccgugagcu ucuuccccca ggcggagacc ugcaaggucc aguccaaccg cguguucugc     1080

gacacgauga acagccggac ccuccccucc gaggucaacc ugugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aaccggggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccucuac ugcgucaaca agcaggaggg gaagucccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aagagcgacg agcugcugca caacgugaac gcggggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cuccugagcc ugaucgccgu gggccuccug     1620

cuguacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5232
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5232
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucugcuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca ucgaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucc aguccaaccg cgucuucugc     1080

gacaccauga acucccgcac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aaccgcggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac ugcgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5233
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5233
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auauguagcg gaguggcagu cugcaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugccc ugcuguccac gaauaaagcu guggucucuc ucagcaacgg uguguccgua      540

uuaacuuuua agguucugga ccuuaagaau uacauugaua aacaauugcu gccuauccua      600

aacaagcagu cauguaguau uagcaauauc gagaccguga uagaguucca gcagaaaaac      660

aauaggcucc uggaaauuac acgggaguuu ucugucaacg ccggggugac uaccccagug      720

uccacauaua ugcuuaccaa uucagaacug uugagccuca ucaacgacau gccgauuacg      780

aacgaucaaa agaaacugau gaguaauaac guccagaucg uucgccagca gucuuacucc      840

aucaugugca uuauaaagga ggaaguguua gcguauguag ugcaacugcc ccucuacgga      900

gucaucgaca cuccuuguug gaaacuucau acaagcccac ugugcaccac uaauacaaag      960

gagggcucga acauuuguuu gacccgaacg gaucguggcu gguacugcga caaugcaggg     1020

ucuguguccu ucuuucccca ggccgaaacc uguaagguuc agucaaacag aguguucugc     1080

gauacaauga auaguagaac ucugccuagc gaggucaacc ucugcaaugu ggacaucuuu     1140

aacccaaaau augauuguaa gauaaugacc uccaaaacag acguaucuag cucaguuauu     1200

accagucugg gagcuaucgu guccugcuac gguaagacua aauguacagc cagcaauaag     1260

aacaggggca ucauuaagac cuucucuaau gggugcgauu augucucaaa caaaggagug     1320

gacacuguca gugugggcaa uacgcuuuac uguguuaaca agcaagaggg uaaaagccug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuu ugguauuccc auccgaugag     1440

uuugacgcau cuauaucgca ggucaaugag aaaaucaacc agagccucgc uuucauucgg     1500

aaguccgaug aacuguuaca caaugugaac gccggaaagu caacaaccaa uaucaugauc     1560

acuaccauua uaaucguuau uaucgugauu cugcuaaguc ucaucgcggu cggccugcuu     1620

uuguauugca aagcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5234
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5234
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucugcagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga ucgaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugc agagcaacag aguguucugc     1080

gacaccauga acagcagaac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacagaggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac ugcgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5235
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5235
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auuuguuccg gcgucgccgu gugcaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgcgc uucugucuac caauaaagcc gucguguccc ucagcaacgg aguuucugug      540

cugacauuua agguccuuga ccugaagaau uacauugaua aacaacuccu gccuauccug      600

aacaagcagu ccuguagcau uucuaauauc gagaccguga uugaguucca gcagaaaaac      660

aaucggcucc uggaaaucac gcgcgaguuu uccgugaacg cuggcgucac aaccccgguu      720

agcacauaua ugcuuaccaa uuccgaacug cucucucuga ucaacgacau gcccauuacc      780

aacgaucaaa agaaacuuau gagcaauaac gugcagaucg ugagacagca guccuacagc      840

auuaugugca ucauuaagga ggaaguccug gccuaugugg uucaacuccc ucuguacggc      900

gugaucgaca cacccuguug gaaacugcau acgucuccuc ucugcaccac aaauaccaag      960

gaggggucca acaucugucu gacacggacc gaucgcggau gguacugcga caaugcuggc     1020

agcgucucuu ucuuucccca ggccgaaacg uguaaggugc agagcaacag aguuuucugc     1080

gauacaauga acuccagaac ccugccuucu gaggugaauc ucugcaaugu cgacauuuuu     1140

aacccgaaau augauuguaa gaucaugacc agcaaaacag acguguccag cucugucauu     1200

accucccugg gggcgaucgu gagcugcuac ggaaagacaa aauguacggc cucuaauaag     1260

aaccggggca uuaucaagac cuucuccaau gggugcgauu auguuagcaa caaaggagug     1320

gacacagucu ccgugggcaa uacccuuuac uguguuaaca agcaagaggg caaaucucug     1380

uaugugaagg gggaacccau cauuaacuuu uacgacccuc ucgucuuccc cagcgaugag     1440

uuugacgcuu ccaucucuca ggugaaugag aaaauuaacc agagccuggc cuucauccgc     1500

aaguccgaug aacugcucca caaugugaac gcuggaaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucaucguuau uaucgucauu cugcuuucuc ugaucgccgu gggccuccug     1620

cuguauugca aagccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5236
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5236
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acuaaaagcu      120

aacgccauaa ccacuauacu aacagcaguc acauucugcu ucgcaucagg ccaaaacaua      180

accgaagaau uuuaccaauc cacuuguuca gcagucucca aaggauauuu auccgcacuu      240

cguacaggau gguauacauc aguaauaaca auagaacucu ccaacauaaa agaaaauaaa      300

ugcaacggca ccgacgcaaa aguaaaacuc aucaaacaag aauuagacaa auacaagaac      360

gccguaacag aacuacaauu acuaaugcaa ucaacacccg ccacaggauc aggaucugca      420

auaugcucug gaguagcagu augcaaagua uuacaccuag aaggagaagu aaacaaaauc      480

aaaagcgcac uacuauccac aaacaaagcu guaguaucac uaucaaacgg aguaucagua      540

uuaacuuuca aaguacuuga ucuaaaaaac uacauagaca aacaacuacu acccauauua      600

aacaaacaau caugcucaau aagcaauaua gaaacaguaa uagaauuuca acaaaaaaac      660

aacagacuac uagaaaucac aagggaauuu ucaguaaaug ccgguguuac aaccccagua      720

ucaacauaca ugcuaacuaa cucagaacua cuauccuuaa uaaacgauau gccaauaaca      780

aacgaucaaa aaaaacuaau guccaacaac guacaaauag uaagacaaca aucauacuca      840

aucaugugca uuauaaaaga agaagucuua gcauacguag uacaauuacc acuauacggu      900

guaauagaua caccauguug gaaauuacac acaagcccac uaugcacaac uaacacaaaa      960

gaaggcucaa auauauguuu aacaagaaca gaccgagguu gguacugcga caaugcagga     1020

ucaguaucau ucuuuccaca agcagaaaca uguaaaguuc aauccaacag aguauucugc     1080

gacacaauga acuccagaac acuaccuuca gaaguaaacc ucuguaacgu agacauauuu     1140

aaucccaagu acgacugcaa aauaaugaca ucgaaaacag acguaagcuc cucagugaua     1200

acaucccucg gcgccaucgu auccuguuac gguaaaacua aauguaccgc cucaaacaaa     1260

aaccgcggua uuauaaaaac uuuuucuaau ggcugcgauu acguaagcaa caaaggcguc     1320

gacacaguuu ccguaggaaa cacacuauac ugcguaaaca aacaagaagg uaaaucucua     1380

uacguaaaag gagaaccaau aauaaauuuc uaugauccuu uaguauuccc auccgaugaa     1440

uuugacgccu cuaucucaca agucaacgaa aaaauaaauc aaucauuagc auucauacga     1500

aaaucagacg aacuacuaca caacguaaac gcaggaaaau caacaaccaa cauaaugaua     1560

accacaauaa uaauaguuau uauagugaua cuauuauccu uaauugcagu cggacuauua     1620

uuauacugua aagcacgcua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5237
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5237
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aaugccauca ccacaauccu gacagcagua accuucugcu ucgcauccgg acaaaacauc      180

accgaagaau uuuaccaguc aaccugcucc gcugucucaa aaggcuaccu cucagcccuu      240

cgcaccggcu gguacaccuc ggucauaaca auagaacucu ccaauaucaa agaaaacaaa      300

ugcaacggca cugacgccaa gguaaaacuc aucaaacagg aacucgauaa auacaagaac      360

gccguaacag aacuacaacu acucaugcaa ucaacaccgg ccaccggcuc cgguuccgcc      420

auaugcuccg gaguggccgu gugcaagguc cuccaccuug aaggggaagu uaacaaaauc      480

aaaucagccc uccucuccac uaacaaagcc guaguauccc uaagcaacgg uguauccguc      540

cucaccuuca aaguacuaga ccuaaagaau uauaucgaca aacaacuccu ccccauacuc      600

aacaaacaau ccugcuccau aagcaacauc gaaacaguca ucgaguucca gcagaaaaac      660

aaccgacucc ucgaaauaac ccgcgaguuc ucagucaacg ccggagucac cacacccguc      720

agcaccuaca ugcugaccaa cuccgaacuc cucuccuuaa ucaaugacau gcccaucacc      780

aaugaccaaa agaaacucau gucaaacaac guccaaauag uacgccaaca auccuacucc      840

aucaugugca ucauaaaaga agaaguacuc gccuacgucg uccaacuccc ccucuacggc      900

guaaucgaca cccccugcug gaaacuacac acaagccccc ucugcaccac aaacacuaaa      960

gagggcucca acaucugucu aacccgcacc gaucgaggcu gguacugcga caacgccgga     1020

ucugucucau ucuuccccca agccgaaacc ugcaaagucc aauccaaccg cgucuucugc     1080

gacaccauga acucgagaac ccucccuucc gaagucaacc uaugcaacgu cgacauuuuc     1140

aaccccaaau acgacugcaa aaucaugacc ucgaaaaccg acguaucauc cagcgucauc     1200

accagccuag gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc gagcaauaaa     1260

aaccgcggga ucaucaaaac uuucuccaac ggcugcgacu acgucuccaa caagggaguc     1320

gauaccgucu ccguaggcaa cacccucuac ugcgucaaca aacaagaagg caaaucacua     1380

uacguaaaag gcgagccaau cauaaacuuc uacgacccuc uaguuuuccc auccgacgag     1440

uucgacgcua gcaucuccca agucaacgag aaaaucaacc aaucccucgc auucauccgc     1500

aaauccgacg aacuccucca caacguaaac gcaggcaaau caacuacuaa uauaaugauc     1560

acaaccauca uaauagucau aaucguaauc cuccuauccc ucaucgccgu cggacuacug     1620

cucuacugca aagcccgcua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  5238
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5238
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5239
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5239
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug      540

gucucccuca gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac      600

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac     1020

cggggguggu acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc     1080

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1140

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc     1380

gucaacaagc aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1620

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5240
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5240
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5241
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5241
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug      540

gucucucuca gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac      600

auugauaaac aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag      660

accgugauag aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu      720

gucaacgccg gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug      780

agccucauca acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc      840

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg      900

uauguagugc aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca      960

agcccacugu gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau     1020

cguggcuggu acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu     1080

aagguucagu caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag     1140

gucaaccucu gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc     1200

aaaacagacg uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu     1260

aagacuaaau guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg     1320

ugcgauuaug ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu     1380

guuaacaagc aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccuuugg uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa     1500

aucaaccaga gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc     1560

ggaaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1620

cuaagucuca ucgcggucgg ccugcuuuug uauugcaaag cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5242
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5242
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5243
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5243
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc      540

gugucccuca gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac      600

auugauaaac aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag      660

accgugauug aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc      720

gugaacgcug gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc      780

ucucugauca acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug      840

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc      900

uaugugguuc aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg      960

ucuccucucu gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau     1020

cgcggauggu acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu     1080

aaggugcaga gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1140

gugaaucucu gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc     1200

aaaacagacg uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga     1260

aagacaaaau guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg     1320

ugcgauuaug uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu     1380

guuaacaagc aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac     1440

gacccucucg ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa     1500

auuaaccaga gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu     1560

ggaaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1620

cuuucucuga ucgccguggg ccuccugcug uauugcaaag ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5244
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5244
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu aaaagcuaac gccauaacca cuauacuaac agcagucaca      180

uucugcuucg caucaggcca aaacauaacc gaagaauuuu accaauccac uuguucagca      240

gucuccaaag gauauuuauc cgcacuucgu acaggauggu auacaucagu aauaacaaua      300

gaacucucca acauaaaaga aaauaaaugc aacggcaccg acgcaaaagu aaaacucauc      360

aaacaagaau uagacaaaua caagaacgcc guaacagaac uacaauuacu aaugcaauca      420

acacccgcca caggaucagg aucugcaaua ugcucuggag uagcaguaug caaaguauua      480

caccuagaag gagaaguaaa caaaaucaaa agcgcacuac uauccacaaa caaagcugua      540

guaucacuau caaacggagu aucaguauua acuuucaaag uacuugaucu aaaaaacuac      600

auagacaaac aacuacuacc cauauuaaac aaacaaucau gcucaauaag caauauagaa      660

acaguaauag aauuucaaca aaaaaacaac agacuacuag aaaucacaag ggaauuuuca      720

guaaaugccg guguuacaac cccaguauca acauacaugc uaacuaacuc agaacuacua      780

uccuuaauaa acgauaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua      840

caaauaguaa gacaacaauc auacucaauc augugcauua uaaaagaaga agucuuagca      900

uacguaguac aauuaccacu auacggugua auagauacac cauguuggaa auuacacaca      960

agcccacuau gcacaacuaa cacaaaagaa ggcucaaaua uauguuuaac aagaacagac     1020

cgagguuggu acugcgacaa ugcaggauca guaucauucu uuccacaagc agaaacaugu     1080

aaaguucaau ccaacagagu auucugcgac acaaugaacu ccagaacacu accuucagaa     1140

guaaaccucu guaacguaga cauauuuaau cccaaguacg acugcaaaau aaugacaucg     1200

aaaacagacg uaagcuccuc agugauaaca ucccucggcg ccaucguauc cuguuacggu     1260

aaaacuaaau guaccgccuc aaacaaaaac cgcgguauua uaaaaacuuu uucuaauggc     1320

ugcgauuacg uaagcaacaa aggcgucgac acaguuuccg uaggaaacac acuauacugc     1380

guaaacaaac aagaagguaa aucucuauac guaaaaggag aaccaauaau aaauuucuau     1440

gauccuuuag uauucccauc cgaugaauuu gacgccucua ucucacaagu caacgaaaaa     1500

auaaaucaau cauuagcauu cauacgaaaa ucagacgaac uacuacacaa cguaaacgca     1560

ggaaaaucaa caaccaacau aaugauaacc acaauaauaa uaguuauuau agugauacua     1620

uuauccuuaa uugcagucgg acuauuauua uacuguaaag cacgcuaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5245
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5245
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaau gccaucacca caauccugac agcaguaacc      180

uucugcuucg cauccggaca aaacaucacc gaagaauuuu accagucaac cugcuccgcu      240

gucucaaaag gcuaccucuc agcccuucgc accggcuggu acaccucggu cauaacaaua      300

gaacucucca auaucaaaga aaacaaaugc aacggcacug acgccaaggu aaaacucauc      360

aaacaggaac ucgauaaaua caagaacgcc guaacagaac uacaacuacu caugcaauca      420

acaccggcca ccggcuccgg uuccgccaua ugcuccggag uggccgugug caagguccuc      480

caccuugaag gggaaguuaa caaaaucaaa ucagcccucc ucuccacuaa caaagccgua      540

guaucccuaa gcaacggugu auccguccuc accuucaaag uacuagaccu aaagaauuau      600

aucgacaaac aacuccuccc cauacucaac aaacaauccu gcuccauaag caacaucgaa      660

acagucaucg aguuccagca gaaaaacaac cgacuccucg aaauaacccg cgaguucuca      720

gucaacgccg gagucaccac acccgucagc accuacaugc ugaccaacuc cgaacuccuc      780

uccuuaauca augacaugcc caucaccaau gaccaaaaga aacucauguc aaacaacguc      840

caaauaguac gccaacaauc cuacuccauc augugcauca uaaaagaaga aguacucgcc      900

uacgucgucc aacucccccu cuacggcgua aucgacaccc ccugcuggaa acuacacaca      960

agcccccucu gcaccacaaa cacuaaagag ggcuccaaca ucugucuaac ccgcaccgau     1020

cgaggcuggu acugcgacaa cgccggaucu gucucauucu ucccccaagc cgaaaccugc     1080

aaaguccaau ccaaccgcgu cuucugcgac accaugaacu cgagaacccu cccuuccgaa     1140

gucaaccuau gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucg     1200

aaaaccgacg uaucauccag cgucaucacc agccuaggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgcgag caauaaaaac cgcgggauca ucaaaacuuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggagucgau accgucuccg uaggcaacac ccucuacugc     1380

gucaacaaac aagaaggcaa aucacuauac guaaaaggcg agccaaucau aaacuucuac     1440

gacccucuag uuuucccauc cgacgaguuc gacgcuagca ucucccaagu caacgagaaa     1500

aucaaccaau cccucgcauu cauccgcaaa uccgacgaac uccuccacaa cguaaacgca     1560

ggcaaaucaa cuacuaauau aaugaucaca accaucauaa uagucauaau cguaauccuc     1620

cuaucccuca ucgccgucgg acuacugcuc uacugcaaag cccgcuaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5246
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5246
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5247
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5247
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5248
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5248
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5249
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5249
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5250
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5250
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5251
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5251
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5252
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5252
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacuaaaa      120

gcuaacgcca uaaccacuau acuaacagca gucacauucu gcuucgcauc aggccaaaac      180

auaaccgaag aauuuuacca auccacuugu ucagcagucu ccaaaggaua uuuauccgca      240

cuucguacag gaugguauac aucaguaaua acaauagaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc aaaaguaaaa cucaucaaac aagaauuaga caaauacaag      360

aacgccguaa cagaacuaca auuacuaaug caaucaacac ccgccacagg aucaggaucu      420

gcaauaugcu cuggaguagc aguaugcaaa guauuacacc uagaaggaga aguaaacaaa      480

aucaaaagcg cacuacuauc cacaaacaaa gcuguaguau cacuaucaaa cggaguauca      540

guauuaacuu ucaaaguacu ugaucuaaaa aacuacauag acaaacaacu acuacccaua      600

uuaaacaaac aaucaugcuc aauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uacuagaaau cacaagggaa uuuucaguaa augccggugu uacaacccca      720

guaucaacau acaugcuaac uaacucagaa cuacuauccu uaauaaacga uaugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauuauaaa agaagaaguc uuagcauacg uaguacaauu accacuauac      900

gguguaauag auacaccaug uuggaaauua cacacaagcc cacuaugcac aacuaacaca      960

aaagaaggcu caaauauaug uuuaacaaga acagaccgag guugguacug cgacaaugca     1020

ggaucaguau cauucuuucc acaagcagaa acauguaaag uucaauccaa cagaguauuc     1080

ugcgacacaa ugaacuccag aacacuaccu ucagaaguaa accucuguaa cguagacaua     1140

uuuaauccca aguacgacug caaaauaaug acaucgaaaa cagacguaag cuccucagug     1200

auaacauccc ucggcgccau cguauccugu uacgguaaaa cuaaauguac cgccucaaac     1260

aaaaaccgcg guauuauaaa aacuuuuucu aauggcugcg auuacguaag caacaaaggc     1320

gucgacacag uuuccguagg aaacacacua uacugcguaa acaaacaaga agguaaaucu     1380

cuauacguaa aaggagaacc aauaauaaau uucuaugauc cuuuaguauu cccauccgau     1440

gaauuugacg ccucuaucuc acaagucaac gaaaaaauaa aucaaucauu agcauucaua     1500

cgaaaaucag acgaacuacu acacaacgua aacgcaggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaauagu uauuauagug auacuauuau ccuuaauugc agucggacua     1620

uuauuauacu guaaagcacg cuaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5253
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5253
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaaugcca ucaccacaau ccugacagca guaaccuucu gcuucgcauc cggacaaaac      180

aucaccgaag aauuuuacca gucaaccugc uccgcugucu caaaaggcua ccucucagcc      240

cuucgcaccg gcugguacac cucggucaua acaauagaac ucuccaauau caaagaaaac      300

aaaugcaacg gcacugacgc caagguaaaa cucaucaaac aggaacucga uaaauacaag      360

aacgccguaa cagaacuaca acuacucaug caaucaacac cggccaccgg cuccgguucc      420

gccauaugcu ccggaguggc cgugugcaag guccuccacc uugaagggga aguuaacaaa      480

aucaaaucag cccuccucuc cacuaacaaa gccguaguau cccuaagcaa cgguguaucc      540

guccucaccu ucaaaguacu agaccuaaag aauuauaucg acaaacaacu ccuccccaua      600

cucaacaaac aauccugcuc cauaagcaac aucgaaacag ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau aacccgcgag uucucaguca acgccggagu caccacaccc      720

gucagcaccu acaugcugac caacuccgaa cuccucuccu uaaucaauga caugcccauc      780

accaaugacc aaaagaaacu caugucaaac aacguccaaa uaguacgcca acaauccuac      840

uccaucaugu gcaucauaaa agaagaagua cucgccuacg ucguccaacu cccccucuac      900

ggcguaaucg acacccccug cuggaaacua cacacaagcc cccucugcac cacaaacacu      960

aaagagggcu ccaacaucug ucuaacccgc accgaucgag gcugguacug cgacaacgcc     1020

ggaucugucu cauucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucgag aacccucccu uccgaaguca accuaugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accucgaaaa ccgacguauc auccagcguc     1200

aucaccagcc uaggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgcgagcaau     1260

aaaaaccgcg ggaucaucaa aacuuucucc aacggcugcg acuacgucuc caacaaggga     1320

gucgauaccg ucuccguagg caacacccuc uacugcguca acaaacaaga aggcaaauca     1380

cuauacguaa aaggcgagcc aaucauaaac uucuacgacc cucuaguuuu cccauccgac     1440

gaguucgacg cuagcaucuc ccaagucaac gagaaaauca accaaucccu cgcauucauc     1500

cgcaaauccg acgaacuccu ccacaacgua aacgcaggca aaucaacuac uaauauaaug     1560

aucacaacca ucauaauagu cauaaucgua auccuccuau cccucaucgc cgucggacua     1620

cugcucuacu gcaaagcccg cuaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5254
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5254
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5255
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5255
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5256
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5256
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5257
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5257
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5258
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5258
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5259
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5259
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5260
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5260
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacuaaaa      120

gcuaacgcca uaaccacuau acuaacagca gucacauucu gcuucgcauc aggccaaaac      180

auaaccgaag aauuuuacca auccacuugu ucagcagucu ccaaaggaua uuuauccgca      240

cuucguacag gaugguauac aucaguaaua acaauagaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc aaaaguaaaa cucaucaaac aagaauuaga caaauacaag      360

aacgccguaa cagaacuaca auuacuaaug caaucaacac ccgccacagg aucaggaucu      420

gcaauaugcu cuggaguagc aguaugcaaa guauuacacc uagaaggaga aguaaacaaa      480

aucaaaagcg cacuacuauc cacaaacaaa gcuguaguau cacuaucaaa cggaguauca      540

guauuaacuu ucaaaguacu ugaucuaaaa aacuacauag acaaacaacu acuacccaua      600

uuaaacaaac aaucaugcuc aauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uacuagaaau cacaagggaa uuuucaguaa augccggugu uacaacccca      720

guaucaacau acaugcuaac uaacucagaa cuacuauccu uaauaaacga uaugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauuauaaa agaagaaguc uuagcauacg uaguacaauu accacuauac      900

gguguaauag auacaccaug uuggaaauua cacacaagcc cacuaugcac aacuaacaca      960

aaagaaggcu caaauauaug uuuaacaaga acagaccgag guugguacug cgacaaugca     1020

ggaucaguau cauucuuucc acaagcagaa acauguaaag uucaauccaa cagaguauuc     1080

ugcgacacaa ugaacuccag aacacuaccu ucagaaguaa accucuguaa cguagacaua     1140

uuuaauccca aguacgacug caaaauaaug acaucgaaaa cagacguaag cuccucagug     1200

auaacauccc ucggcgccau cguauccugu uacgguaaaa cuaaauguac cgccucaaac     1260

aaaaaccgcg guauuauaaa aacuuuuucu aauggcugcg auuacguaag caacaaaggc     1320

gucgacacag uuuccguagg aaacacacua uacugcguaa acaaacaaga agguaaaucu     1380

cuauacguaa aaggagaacc aauaauaaau uucuaugauc cuuuaguauu cccauccgau     1440

gaauuugacg ccucuaucuc acaagucaac gaaaaaauaa aucaaucauu agcauucaua     1500

cgaaaaucag acgaacuacu acacaacgua aacgcaggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaauagu uauuauagug auacuauuau ccuuaauugc agucggacua     1620

uuauuauacu guaaagcacg cuaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5261
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5261
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaaugcca ucaccacaau ccugacagca guaaccuucu gcuucgcauc cggacaaaac      180

aucaccgaag aauuuuacca gucaaccugc uccgcugucu caaaaggcua ccucucagcc      240

cuucgcaccg gcugguacac cucggucaua acaauagaac ucuccaauau caaagaaaac      300

aaaugcaacg gcacugacgc caagguaaaa cucaucaaac aggaacucga uaaauacaag      360

aacgccguaa cagaacuaca acuacucaug caaucaacac cggccaccgg cuccgguucc      420

gccauaugcu ccggaguggc cgugugcaag guccuccacc uugaagggga aguuaacaaa      480

aucaaaucag cccuccucuc cacuaacaaa gccguaguau cccuaagcaa cgguguaucc      540

guccucaccu ucaaaguacu agaccuaaag aauuauaucg acaaacaacu ccuccccaua      600

cucaacaaac aauccugcuc cauaagcaac aucgaaacag ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau aacccgcgag uucucaguca acgccggagu caccacaccc      720

gucagcaccu acaugcugac caacuccgaa cuccucuccu uaaucaauga caugcccauc      780

accaaugacc aaaagaaacu caugucaaac aacguccaaa uaguacgcca acaauccuac      840

uccaucaugu gcaucauaaa agaagaagua cucgccuacg ucguccaacu cccccucuac      900

ggcguaaucg acacccccug cuggaaacua cacacaagcc cccucugcac cacaaacacu      960

aaagagggcu ccaacaucug ucuaacccgc accgaucgag gcugguacug cgacaacgcc     1020

ggaucugucu cauucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucgag aacccucccu uccgaaguca accuaugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accucgaaaa ccgacguauc auccagcguc     1200

aucaccagcc uaggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgcgagcaau     1260

aaaaaccgcg ggaucaucaa aacuuucucc aacggcugcg acuacgucuc caacaaggga     1320

gucgauaccg ucuccguagg caacacccuc uacugcguca acaaacaaga aggcaaauca     1380

cuauacguaa aaggcgagcc aaucauaaac uucuacgacc cucuaguuuu cccauccgac     1440

gaguucgacg cuagcaucuc ccaagucaac gagaaaauca accaaucccu cgcauucauc     1500

cgcaaauccg acgaacuccu ccacaacgua aacgcaggca aaucaacuac uaauauaaug     1560

aucacaacca ucauaauagu cauaaucgua auccuccuau cccucaucgc cgucggacua     1620

cugcucuacu gcaaagcccg cuaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5262
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5262
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5263
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5263
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5264
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5264
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5265
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5265
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5266
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5266
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5267
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5267
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5268
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5268
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacuaaaa      120

gcuaacgcca uaaccacuau acuaacagca gucacauucu gcuucgcauc aggccaaaac      180

auaaccgaag aauuuuacca auccacuugu ucagcagucu ccaaaggaua uuuauccgca      240

cuucguacag gaugguauac aucaguaaua acaauagaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc aaaaguaaaa cucaucaaac aagaauuaga caaauacaag      360

aacgccguaa cagaacuaca auuacuaaug caaucaacac ccgccacagg aucaggaucu      420

gcaauaugcu cuggaguagc aguaugcaaa guauuacacc uagaaggaga aguaaacaaa      480

aucaaaagcg cacuacuauc cacaaacaaa gcuguaguau cacuaucaaa cggaguauca      540

guauuaacuu ucaaaguacu ugaucuaaaa aacuacauag acaaacaacu acuacccaua      600

uuaaacaaac aaucaugcuc aauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uacuagaaau cacaagggaa uuuucaguaa augccggugu uacaacccca      720

guaucaacau acaugcuaac uaacucagaa cuacuauccu uaauaaacga uaugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauuauaaa agaagaaguc uuagcauacg uaguacaauu accacuauac      900

gguguaauag auacaccaug uuggaaauua cacacaagcc cacuaugcac aacuaacaca      960

aaagaaggcu caaauauaug uuuaacaaga acagaccgag guugguacug cgacaaugca     1020

ggaucaguau cauucuuucc acaagcagaa acauguaaag uucaauccaa cagaguauuc     1080

ugcgacacaa ugaacuccag aacacuaccu ucagaaguaa accucuguaa cguagacaua     1140

uuuaauccca aguacgacug caaaauaaug acaucgaaaa cagacguaag cuccucagug     1200

auaacauccc ucggcgccau cguauccugu uacgguaaaa cuaaauguac cgccucaaac     1260

aaaaaccgcg guauuauaaa aacuuuuucu aauggcugcg auuacguaag caacaaaggc     1320

gucgacacag uuuccguagg aaacacacua uacugcguaa acaaacaaga agguaaaucu     1380

cuauacguaa aaggagaacc aauaauaaau uucuaugauc cuuuaguauu cccauccgau     1440

gaauuugacg ccucuaucuc acaagucaac gaaaaaauaa aucaaucauu agcauucaua     1500

cgaaaaucag acgaacuacu acacaacgua aacgcaggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaauagu uauuauagug auacuauuau ccuuaauugc agucggacua     1620

uuauuauacu guaaagcacg cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5269
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5269
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaaugcca ucaccacaau ccugacagca guaaccuucu gcuucgcauc cggacaaaac      180

aucaccgaag aauuuuacca gucaaccugc uccgcugucu caaaaggcua ccucucagcc      240

cuucgcaccg gcugguacac cucggucaua acaauagaac ucuccaauau caaagaaaac      300

aaaugcaacg gcacugacgc caagguaaaa cucaucaaac aggaacucga uaaauacaag      360

aacgccguaa cagaacuaca acuacucaug caaucaacac cggccaccgg cuccgguucc      420

gccauaugcu ccggaguggc cgugugcaag guccuccacc uugaagggga aguuaacaaa      480

aucaaaucag cccuccucuc cacuaacaaa gccguaguau cccuaagcaa cgguguaucc      540

guccucaccu ucaaaguacu agaccuaaag aauuauaucg acaaacaacu ccuccccaua      600

cucaacaaac aauccugcuc cauaagcaac aucgaaacag ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau aacccgcgag uucucaguca acgccggagu caccacaccc      720

gucagcaccu acaugcugac caacuccgaa cuccucuccu uaaucaauga caugcccauc      780

accaaugacc aaaagaaacu caugucaaac aacguccaaa uaguacgcca acaauccuac      840

uccaucaugu gcaucauaaa agaagaagua cucgccuacg ucguccaacu cccccucuac      900

ggcguaaucg acacccccug cuggaaacua cacacaagcc cccucugcac cacaaacacu      960

aaagagggcu ccaacaucug ucuaacccgc accgaucgag gcugguacug cgacaacgcc     1020

ggaucugucu cauucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucgag aacccucccu uccgaaguca accuaugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accucgaaaa ccgacguauc auccagcguc     1200

aucaccagcc uaggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgcgagcaau     1260

aaaaaccgcg ggaucaucaa aacuuucucc aacggcugcg acuacgucuc caacaaggga     1320

gucgauaccg ucuccguagg caacacccuc uacugcguca acaaacaaga aggcaaauca     1380

cuauacguaa aaggcgagcc aaucauaaac uucuacgacc cucuaguuuu cccauccgac     1440

gaguucgacg cuagcaucuc ccaagucaac gagaaaauca accaaucccu cgcauucauc     1500

cgcaaauccg acgaacuccu ccacaacgua aacgcaggca aaucaacuac uaauauaaug     1560

aucacaacca ucauaauagu cauaaucgua auccuccuau cccucaucgc cgucggacua     1620

cugcucuacu gcaaagcccg cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5270
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5270
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucugca gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaaccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacugcguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5271
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5271
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucugca gcggcguggc cgugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cgcugcugag caccaacaag gccguggucu cccucagcaa cggggugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg ggugguacug cgacaacgcc     1020

ggcuccguga gcuucuuccc ccaggcggag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaaccggg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccuc uacugcguca acaagcagga ggggaagucc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgcgggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5272
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5272
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucugcu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaaccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacugcguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5273
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5273
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauaugua gcggaguggc agucugcaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cccugcuguc cacgaauaaa gcuguggucu cucucagcaa cggugugucc      540

guauuaacuu uuaagguucu ggaccuuaag aauuacauug auaaacaauu gcugccuauc      600

cuaaacaagc agucauguag uauuagcaau aucgagaccg ugauagaguu ccagcagaaa      660

aacaauaggc uccuggaaau uacacgggag uuuucuguca acgccggggu gacuacccca      720

guguccacau auaugcuuac caauucagaa cuguugagcc ucaucaacga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaau aacguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcguaug uagugcaacu gccccucuac      900

ggagucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaauaca      960

aaggagggcu cgaacauuug uuugacccga acggaucgug gcugguacug cgacaaugca     1020

gggucugugu ccuucuuucc ccaggccgaa accuguaagg uucagucaaa cagaguguuc     1080

ugcgauacaa ugaauaguag aacucugccu agcgagguca accucugcaa uguggacauc     1140

uuuaacccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggagcuau cguguccugc uacgguaaga cuaaauguac agccagcaau     1260

aagaacaggg gcaucauuaa gaccuucucu aaugggugcg auuaugucuc aaacaaagga     1320

guggacacug ucaguguggg caauacgcuu uacuguguua acaagcaaga ggguaaaagc     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cuuugguauu cccauccgau     1440

gaguuugacg caucuauauc gcaggucaau gagaaaauca accagagccu cgcuuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgccggaa agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc ggucggccug     1620

cuuuuguauu gcaaagcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5274
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5274
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucugca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacugcguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5275
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5275
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauuuguu ccggcgucgc cgugugcaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cgcuucuguc uaccaauaaa gccgucgugu cccucagcaa cggaguuucu      540

gugcugacau uuaagguccu ugaccugaag aauuacauug auaaacaacu ccugccuauc      600

cugaacaagc aguccuguag cauuucuaau aucgagaccg ugauugaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuuccguga acgcuggcgu cacaaccccg      720

guuagcacau auaugcuuac caauuccgaa cugcucucuc ugaucaacga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaau aacgugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggccuaug ugguucaacu cccucuguac      900

ggcgugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaauacc      960

aaggaggggu ccaacaucug ucugacacgg accgaucgcg gaugguacug cgacaaugcu     1020

ggcagcgucu cuuucuuucc ccaggccgaa acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa ugucgacauu     1140

uuuaacccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggggcgau cgugagcugc uacggaaaga caaaauguac ggccucuaau     1260

aagaaccggg gcauuaucaa gaccuucucc aaugggugcg auuauguuag caacaaagga     1320

guggacacag ucuccguggg caauacccuu uacuguguua acaagcaaga gggcaaaucu     1380

cuguauguga agggggaacc caucauuaac uuuuacgacc cucucgucuu ccccagcgau     1440

gaguuugacg cuuccaucuc ucaggugaau gagaaaauua accagagccu ggccuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgcuggaa agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cgugggccuc     1620

cugcuguauu gcaaagccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5276
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5276
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacuaaaa      120

gcuaacgcca uaaccacuau acuaacagca gucacauucu gcuucgcauc aggccaaaac      180

auaaccgaag aauuuuacca auccacuugu ucagcagucu ccaaaggaua uuuauccgca      240

cuucguacag gaugguauac aucaguaaua acaauagaac ucuccaacau aaaagaaaau      300

aaaugcaacg gcaccgacgc aaaaguaaaa cucaucaaac aagaauuaga caaauacaag      360

aacgccguaa cagaacuaca auuacuaaug caaucaacac ccgccacagg aucaggaucu      420

gcaauaugcu cuggaguagc aguaugcaaa guauuacacc uagaaggaga aguaaacaaa      480

aucaaaagcg cacuacuauc cacaaacaaa gcuguaguau cacuaucaaa cggaguauca      540

guauuaacuu ucaaaguacu ugaucuaaaa aacuacauag acaaacaacu acuacccaua      600

uuaaacaaac aaucaugcuc aauaagcaau auagaaacag uaauagaauu ucaacaaaaa      660

aacaacagac uacuagaaau cacaagggaa uuuucaguaa augccggugu uacaacccca      720

guaucaacau acaugcuaac uaacucagaa cuacuauccu uaauaaacga uaugccaaua      780

acaaacgauc aaaaaaaacu aauguccaac aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauuauaaa agaagaaguc uuagcauacg uaguacaauu accacuauac      900

gguguaauag auacaccaug uuggaaauua cacacaagcc cacuaugcac aacuaacaca      960

aaagaaggcu caaauauaug uuuaacaaga acagaccgag guugguacug cgacaaugca     1020

ggaucaguau cauucuuucc acaagcagaa acauguaaag uucaauccaa cagaguauuc     1080

ugcgacacaa ugaacuccag aacacuaccu ucagaaguaa accucuguaa cguagacaua     1140

uuuaauccca aguacgacug caaaauaaug acaucgaaaa cagacguaag cuccucagug     1200

auaacauccc ucggcgccau cguauccugu uacgguaaaa cuaaauguac cgccucaaac     1260

aaaaaccgcg guauuauaaa aacuuuuucu aauggcugcg auuacguaag caacaaaggc     1320

gucgacacag uuuccguagg aaacacacua uacugcguaa acaaacaaga agguaaaucu     1380

cuauacguaa aaggagaacc aauaauaaau uucuaugauc cuuuaguauu cccauccgau     1440

gaauuugacg ccucuaucuc acaagucaac gaaaaaauaa aucaaucauu agcauucaua     1500

cgaaaaucag acgaacuacu acacaacgua aacgcaggaa aaucaacaac caacauaaug     1560

auaaccacaa uaauaauagu uauuauagug auacuauuau ccuuaauugc agucggacua     1620

uuauuauacu guaaagcacg cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5277
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5277
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaaugcca ucaccacaau ccugacagca guaaccuucu gcuucgcauc cggacaaaac      180

aucaccgaag aauuuuacca gucaaccugc uccgcugucu caaaaggcua ccucucagcc      240

cuucgcaccg gcugguacac cucggucaua acaauagaac ucuccaauau caaagaaaac      300

aaaugcaacg gcacugacgc caagguaaaa cucaucaaac aggaacucga uaaauacaag      360

aacgccguaa cagaacuaca acuacucaug caaucaacac cggccaccgg cuccgguucc      420

gccauaugcu ccggaguggc cgugugcaag guccuccacc uugaagggga aguuaacaaa      480

aucaaaucag cccuccucuc cacuaacaaa gccguaguau cccuaagcaa cgguguaucc      540

guccucaccu ucaaaguacu agaccuaaag aauuauaucg acaaacaacu ccuccccaua      600

cucaacaaac aauccugcuc cauaagcaac aucgaaacag ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau aacccgcgag uucucaguca acgccggagu caccacaccc      720

gucagcaccu acaugcugac caacuccgaa cuccucuccu uaaucaauga caugcccauc      780

accaaugacc aaaagaaacu caugucaaac aacguccaaa uaguacgcca acaauccuac      840

uccaucaugu gcaucauaaa agaagaagua cucgccuacg ucguccaacu cccccucuac      900

ggcguaaucg acacccccug cuggaaacua cacacaagcc cccucugcac cacaaacacu      960

aaagagggcu ccaacaucug ucuaacccgc accgaucgag gcugguacug cgacaacgcc     1020

ggaucugucu cauucuuccc ccaagccgaa accugcaaag uccaauccaa ccgcgucuuc     1080

ugcgacacca ugaacucgag aacccucccu uccgaaguca accuaugcaa cgucgacauu     1140

uucaacccca aauacgacug caaaaucaug accucgaaaa ccgacguauc auccagcguc     1200

aucaccagcc uaggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgcgagcaau     1260

aaaaaccgcg ggaucaucaa aacuuucucc aacggcugcg acuacgucuc caacaaggga     1320

gucgauaccg ucuccguagg caacacccuc uacugcguca acaaacaaga aggcaaauca     1380

cuauacguaa aaggcgagcc aaucauaaac uucuacgacc cucuaguuuu cccauccgac     1440

gaguucgacg cuagcaucuc ccaagucaac gagaaaauca accaaucccu cgcauucauc     1500

cgcaaauccg acgaacuccu ccacaacgua aacgcaggca aaucaacuac uaauauaaug     1560

aucacaacca ucauaauagu cauaaucgua auccuccuau cccucaucgc cgucggacua     1620

cugcucuacu gcaaagcccg cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5278
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5278
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5279
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5279
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5280
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5280
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5281
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5281
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5282
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5282
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5283
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5283
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5284
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5284
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac uaaaagcuaa cgccauaacc acuauacuaa cagcagucac auucugcuuc      240

gcaucaggcc aaaacauaac cgaagaauuu uaccaaucca cuuguucagc agucuccaaa      300

ggauauuuau ccgcacuucg uacaggaugg uauacaucag uaauaacaau agaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgcaaaag uaaaacucau caaacaagaa      420

uuagacaaau acaagaacgc cguaacagaa cuacaauuac uaaugcaauc aacacccgcc      480

acaggaucag gaucugcaau augcucugga guagcaguau gcaaaguauu acaccuagaa      540

ggagaaguaa acaaaaucaa aagcgcacua cuauccacaa acaaagcugu aguaucacua      600

ucaaacggag uaucaguauu aacuuucaaa guacuugauc uaaaaaacua cauagacaaa      660

caacuacuac ccauauuaaa caaacaauca ugcucaauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuacua gaaaucacaa gggaauuuuc aguaaaugcc      780

gguguuacaa ccccaguauc aacauacaug cuaacuaacu cagaacuacu auccuuaaua      840

aacgauaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauacucaau caugugcauu auaaaagaag aagucuuagc auacguagua      960

caauuaccac uauacggugu aauagauaca ccauguugga aauuacacac aagcccacua     1020

ugcacaacua acacaaaaga aggcucaaau auauguuuaa caagaacaga ccgagguugg     1080

uacugcgaca augcaggauc aguaucauuc uuuccacaag cagaaacaug uaaaguucaa     1140

uccaacagag uauucugcga cacaaugaac uccagaacac uaccuucaga aguaaaccuc     1200

uguaacguag acauauuuaa ucccaaguac gacugcaaaa uaaugacauc gaaaacagac     1260

guaagcuccu cagugauaac aucccucggc gccaucguau ccuguuacgg uaaaacuaaa     1320

uguaccgccu caaacaaaaa ccgcgguauu auaaaaacuu uuucuaaugg cugcgauuac     1380

guaagcaaca aaggcgucga cacaguuucc guaggaaaca cacuauacug cguaaacaaa     1440

caagaaggua aaucucuaua cguaaaagga gaaccaauaa uaaauuucua ugauccuuua     1500

guauucccau ccgaugaauu ugacgccucu aucucacaag ucaacgaaaa aauaaaucaa     1560

ucauuagcau ucauacgaaa aucagacgaa cuacuacaca acguaaacgc aggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua auaguuauua uagugauacu auuauccuua     1680

auugcagucg gacuauuauu auacuguaaa gcacgcuaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5285
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5285
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa ugccaucacc acaauccuga cagcaguaac cuucugcuuc      240

gcauccggac aaaacaucac cgaagaauuu uaccagucaa ccugcuccgc ugucucaaaa      300

ggcuaccucu cagcccuucg caccggcugg uacaccucgg ucauaacaau agaacucucc      360

aauaucaaag aaaacaaaug caacggcacu gacgccaagg uaaaacucau caaacaggaa      420

cucgauaaau acaagaacgc cguaacagaa cuacaacuac ucaugcaauc aacaccggcc      480

accggcuccg guuccgccau augcuccgga guggccgugu gcaagguccu ccaccuugaa      540

ggggaaguua acaaaaucaa aucagcccuc cucuccacua acaaagccgu aguaucccua      600

agcaacggug uauccguccu caccuucaaa guacuagacc uaaagaauua uaucgacaaa      660

caacuccucc ccauacucaa caaacaaucc ugcuccauaa gcaacaucga aacagucauc      720

gaguuccagc agaaaaacaa ccgacuccuc gaaauaaccc gcgaguucuc agucaacgcc      780

ggagucacca cacccgucag caccuacaug cugaccaacu ccgaacuccu cuccuuaauc      840

aaugacaugc ccaucaccaa ugaccaaaag aaacucaugu caaacaacgu ccaaauagua      900

cgccaacaau ccuacuccau caugugcauc auaaaagaag aaguacucgc cuacgucguc      960

caacuccccc ucuacggcgu aaucgacacc cccugcugga aacuacacac aagcccccuc     1020

ugcaccacaa acacuaaaga gggcuccaac aucugucuaa cccgcaccga ucgaggcugg     1080

uacugcgaca acgccggauc ugucucauuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucgagaaccc ucccuuccga agucaaccua     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc gaaaaccgac     1260

guaucaucca gcgucaucac cagccuaggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgcga gcaauaaaaa ccgcgggauc aucaaaacuu ucuccaacgg cugcgacuac     1380

gucuccaaca agggagucga uaccgucucc guaggcaaca cccucuacug cgucaacaaa     1440

caagaaggca aaucacuaua cguaaaaggc gagccaauca uaaacuucua cgacccucua     1500

guuuucccau ccgacgaguu cgacgcuagc aucucccaag ucaacgagaa aaucaaccaa     1560

ucccucgcau ucauccgcaa auccgacgaa cuccuccaca acguaaacgc aggcaaauca     1620

acuacuaaua uaaugaucac aaccaucaua auagucauaa ucguaauccu ccuaucccuc     1680

aucgccgucg gacuacugcu cuacugcaaa gcccgcuaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5286
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5286
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5287
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5287
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5288
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5288
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5289
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5289
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5290
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5290
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5291
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5291
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5292
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5292
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac uaaaagcuaa cgccauaacc acuauacuaa cagcagucac auucugcuuc      240

gcaucaggcc aaaacauaac cgaagaauuu uaccaaucca cuuguucagc agucuccaaa      300

ggauauuuau ccgcacuucg uacaggaugg uauacaucag uaauaacaau agaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgcaaaag uaaaacucau caaacaagaa      420

uuagacaaau acaagaacgc cguaacagaa cuacaauuac uaaugcaauc aacacccgcc      480

acaggaucag gaucugcaau augcucugga guagcaguau gcaaaguauu acaccuagaa      540

ggagaaguaa acaaaaucaa aagcgcacua cuauccacaa acaaagcugu aguaucacua      600

ucaaacggag uaucaguauu aacuuucaaa guacuugauc uaaaaaacua cauagacaaa      660

caacuacuac ccauauuaaa caaacaauca ugcucaauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuacua gaaaucacaa gggaauuuuc aguaaaugcc      780

gguguuacaa ccccaguauc aacauacaug cuaacuaacu cagaacuacu auccuuaaua      840

aacgauaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauacucaau caugugcauu auaaaagaag aagucuuagc auacguagua      960

caauuaccac uauacggugu aauagauaca ccauguugga aauuacacac aagcccacua     1020

ugcacaacua acacaaaaga aggcucaaau auauguuuaa caagaacaga ccgagguugg     1080

uacugcgaca augcaggauc aguaucauuc uuuccacaag cagaaacaug uaaaguucaa     1140

uccaacagag uauucugcga cacaaugaac uccagaacac uaccuucaga aguaaaccuc     1200

uguaacguag acauauuuaa ucccaaguac gacugcaaaa uaaugacauc gaaaacagac     1260

guaagcuccu cagugauaac aucccucggc gccaucguau ccuguuacgg uaaaacuaaa     1320

uguaccgccu caaacaaaaa ccgcgguauu auaaaaacuu uuucuaaugg cugcgauuac     1380

guaagcaaca aaggcgucga cacaguuucc guaggaaaca cacuauacug cguaaacaaa     1440

caagaaggua aaucucuaua cguaaaagga gaaccaauaa uaaauuucua ugauccuuua     1500

guauucccau ccgaugaauu ugacgccucu aucucacaag ucaacgaaaa aauaaaucaa     1560

ucauuagcau ucauacgaaa aucagacgaa cuacuacaca acguaaacgc aggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua auaguuauua uagugauacu auuauccuua     1680

auugcagucg gacuauuauu auacuguaaa gcacgcuaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5293
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5293
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa ugccaucacc acaauccuga cagcaguaac cuucugcuuc      240

gcauccggac aaaacaucac cgaagaauuu uaccagucaa ccugcuccgc ugucucaaaa      300

ggcuaccucu cagcccuucg caccggcugg uacaccucgg ucauaacaau agaacucucc      360

aauaucaaag aaaacaaaug caacggcacu gacgccaagg uaaaacucau caaacaggaa      420

cucgauaaau acaagaacgc cguaacagaa cuacaacuac ucaugcaauc aacaccggcc      480

accggcuccg guuccgccau augcuccgga guggccgugu gcaagguccu ccaccuugaa      540

ggggaaguua acaaaaucaa aucagcccuc cucuccacua acaaagccgu aguaucccua      600

agcaacggug uauccguccu caccuucaaa guacuagacc uaaagaauua uaucgacaaa      660

caacuccucc ccauacucaa caaacaaucc ugcuccauaa gcaacaucga aacagucauc      720

gaguuccagc agaaaaacaa ccgacuccuc gaaauaaccc gcgaguucuc agucaacgcc      780

ggagucacca cacccgucag caccuacaug cugaccaacu ccgaacuccu cuccuuaauc      840

aaugacaugc ccaucaccaa ugaccaaaag aaacucaugu caaacaacgu ccaaauagua      900

cgccaacaau ccuacuccau caugugcauc auaaaagaag aaguacucgc cuacgucguc      960

caacuccccc ucuacggcgu aaucgacacc cccugcugga aacuacacac aagcccccuc     1020

ugcaccacaa acacuaaaga gggcuccaac aucugucuaa cccgcaccga ucgaggcugg     1080

uacugcgaca acgccggauc ugucucauuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucgagaaccc ucccuuccga agucaaccua     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc gaaaaccgac     1260

guaucaucca gcgucaucac cagccuaggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgcga gcaauaaaaa ccgcgggauc aucaaaacuu ucuccaacgg cugcgacuac     1380

gucuccaaca agggagucga uaccgucucc guaggcaaca cccucuacug cgucaacaaa     1440

caagaaggca aaucacuaua cguaaaaggc gagccaauca uaaacuucua cgacccucua     1500

guuuucccau ccgacgaguu cgacgcuagc aucucccaag ucaacgagaa aaucaaccaa     1560

ucccucgcau ucauccgcaa auccgacgaa cuccuccaca acguaaacgc aggcaaauca     1620

acuacuaaua uaaugaucac aaccaucaua auagucauaa ucguaauccu ccuaucccuc     1680

aucgccgucg gacuacugcu cuacugcaaa gcccgcuaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  5294
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5294
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cugcagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugauc      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugcag     1140

agcaaccgcg uguucugcga caccaugaac ucccggacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacug cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5295
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5295
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cugcagcggc guggccgugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcgcug cugagcacca acaaggccgu ggucucccuc      600

agcaacgggg uguccgugcu gacguucaag guccuggacc ucaagaacua caucgacaag      660

cagcugcugc cgauccucaa caagcagagc ugcuccauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa ccggcugcug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cucaccaaca gcgagcugcu gucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcuccccc uguacggggu gaucgacacg ccgugcugga agcugcacac cagcccccuc     1020

ugcaccacca acacgaagga gggcuccaac aucugccuga cccgcaccga ccgggggugg     1080

uacugcgaca acgccggcuc cgugagcuuc uucccccagg cggagaccug caagguccag     1140

uccaaccgcg uguucugcga cacgaugaac agccggaccc uccccuccga ggucaaccug     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa ccggggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccucuacug cgucaacaag     1440

caggagggga agucccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa gagcgacgag cugcugcaca acgugaacgc ggggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu ccugagccug     1680

aucgccgugg gccuccugcu guacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5296
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5296
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cugcuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucauc      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caagguccag     1140

uccaaccgcg ucuucugcga caccaugaac ucccgcaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa ccgcggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacug cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5297
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5297
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau auguagcgga guggcagucu gcaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcccug cuguccacga auaaagcugu ggucucucuc      600

agcaacggug uguccguauu aacuuuuaag guucuggacc uuaagaauua cauugauaaa      660

caauugcugc cuauccuaaa caagcaguca uguaguauua gcaauaucga gaccgugaua      720

gaguuccagc agaaaaacaa uaggcuccug gaaauuacac gggaguuuuc ugucaacgcc      780

ggggugacua ccccaguguc cacauauaug cuuaccaauu cagaacuguu gagccucauc      840

aacgacaugc cgauuacgaa cgaucaaaag aaacugauga guaauaacgu ccagaucguu      900

cgccagcagu cuuacuccau caugugcauu auaaaggagg aaguguuagc guauguagug      960

caacugcccc ucuacggagu caucgacacu ccuuguugga aacuucauac aagcccacug     1020

ugcaccacua auacaaagga gggcucgaac auuuguuuga cccgaacgga ucguggcugg     1080

uacugcgaca augcaggguc uguguccuuc uuuccccagg ccgaaaccug uaagguucag     1140

ucaaacagag uguucugcga uacaaugaau aguagaacuc ugccuagcga ggucaaccuc     1200

ugcaaugugg acaucuuuaa cccaaaauau gauuguaaga uaaugaccuc caaaacagac     1260

guaucuagcu caguuauuac cagucuggga gcuaucgugu ccugcuacgg uaagacuaaa     1320

uguacagcca gcaauaagaa caggggcauc auuaagaccu ucucuaaugg gugcgauuau     1380

gucucaaaca aaggagugga cacugucagu gugggcaaua cgcuuuacug uguuaacaag     1440

caagagggua aaagccugua ugugaagggg gaacccauca uuaacuuuua cgacccuuug     1500

guauucccau ccgaugaguu ugacgcaucu auaucgcagg ucaaugagaa aaucaaccag     1560

agccucgcuu ucauucggaa guccgaugaa cuguuacaca augugaacgc cggaaaguca     1620

acaaccaaua ucaugaucac uaccauuaua aucguuauua ucgugauucu gcuaagucuc     1680

aucgcggucg gccugcuuuu guauugcaaa gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5298
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5298
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cugcagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugauc      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugcag     1140

agcaacagag uguucugcga caccaugaac agcagaaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa cagaggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacug cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5299
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5299
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau uuguuccggc gucgccgugu gcaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcgcuu cugucuacca auaaagccgu cgugucccuc      600

agcaacggag uuucugugcu gacauuuaag guccuugacc ugaagaauua cauugauaaa      660

caacuccugc cuauccugaa caagcagucc uguagcauuu cuaauaucga gaccgugauu      720

gaguuccagc agaaaaacaa ucggcuccug gaaaucacgc gcgaguuuuc cgugaacgcu      780

ggcgucacaa ccccgguuag cacauauaug cuuaccaauu ccgaacugcu cucucugauc      840

aacgacaugc ccauuaccaa cgaucaaaag aaacuuauga gcaauaacgu gcagaucgug      900

agacagcagu ccuacagcau uaugugcauc auuaaggagg aaguccuggc cuaugugguu      960

caacucccuc uguacggcgu gaucgacaca cccuguugga aacugcauac gucuccucuc     1020

ugcaccacaa auaccaagga gggguccaac aucugucuga cacggaccga ucgcggaugg     1080

uacugcgaca augcuggcag cgucucuuuc uuuccccagg ccgaaacgug uaaggugcag     1140

agcaacagag uuuucugcga uacaaugaac uccagaaccc ugccuucuga ggugaaucuc     1200

ugcaaugucg acauuuuuaa cccgaaauau gauuguaaga ucaugaccag caaaacagac     1260

guguccagcu cugucauuac cucccugggg gcgaucguga gcugcuacgg aaagacaaaa     1320

uguacggccu cuaauaagaa ccggggcauu aucaagaccu ucuccaaugg gugcgauuau     1380

guuagcaaca aaggagugga cacagucucc gugggcaaua cccuuuacug uguuaacaag     1440

caagagggca aaucucugua ugugaagggg gaacccauca uuaacuuuua cgacccucuc     1500

gucuucccca gcgaugaguu ugacgcuucc aucucucagg ugaaugagaa aauuaaccag     1560

agccuggccu ucauccgcaa guccgaugaa cugcuccaca augugaacgc uggaaagagc     1620

acaaccaaua uuaugaucac gaccauuauc aucguuauua ucgucauucu gcuuucucug     1680

aucgccgugg gccuccugcu guauugcaaa gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5300
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5300
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac uaaaagcuaa cgccauaacc acuauacuaa cagcagucac auucugcuuc      240

gcaucaggcc aaaacauaac cgaagaauuu uaccaaucca cuuguucagc agucuccaaa      300

ggauauuuau ccgcacuucg uacaggaugg uauacaucag uaauaacaau agaacucucc      360

aacauaaaag aaaauaaaug caacggcacc gacgcaaaag uaaaacucau caaacaagaa      420

uuagacaaau acaagaacgc cguaacagaa cuacaauuac uaaugcaauc aacacccgcc      480

acaggaucag gaucugcaau augcucugga guagcaguau gcaaaguauu acaccuagaa      540

ggagaaguaa acaaaaucaa aagcgcacua cuauccacaa acaaagcugu aguaucacua      600

ucaaacggag uaucaguauu aacuuucaaa guacuugauc uaaaaaacua cauagacaaa      660

caacuacuac ccauauuaaa caaacaauca ugcucaauaa gcaauauaga aacaguaaua      720

gaauuucaac aaaaaaacaa cagacuacua gaaaucacaa gggaauuuuc aguaaaugcc      780

gguguuacaa ccccaguauc aacauacaug cuaacuaacu cagaacuacu auccuuaaua      840

aacgauaugc caauaacaaa cgaucaaaaa aaacuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauacucaau caugugcauu auaaaagaag aagucuuagc auacguagua      960

caauuaccac uauacggugu aauagauaca ccauguugga aauuacacac aagcccacua     1020

ugcacaacua acacaaaaga aggcucaaau auauguuuaa caagaacaga ccgagguugg     1080

uacugcgaca augcaggauc aguaucauuc uuuccacaag cagaaacaug uaaaguucaa     1140

uccaacagag uauucugcga cacaaugaac uccagaacac uaccuucaga aguaaaccuc     1200

uguaacguag acauauuuaa ucccaaguac gacugcaaaa uaaugacauc gaaaacagac     1260

guaagcuccu cagugauaac aucccucggc gccaucguau ccuguuacgg uaaaacuaaa     1320

uguaccgccu caaacaaaaa ccgcgguauu auaaaaacuu uuucuaaugg cugcgauuac     1380

guaagcaaca aaggcgucga cacaguuucc guaggaaaca cacuauacug cguaaacaaa     1440

caagaaggua aaucucuaua cguaaaagga gaaccaauaa uaaauuucua ugauccuuua     1500

guauucccau ccgaugaauu ugacgccucu aucucacaag ucaacgaaaa aauaaaucaa     1560

ucauuagcau ucauacgaaa aucagacgaa cuacuacaca acguaaacgc aggaaaauca     1620

acaaccaaca uaaugauaac cacaauaaua auaguuauua uagugauacu auuauccuua     1680

auugcagucg gacuauuauu auacuguaaa gcacgcuaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5301
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5301
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa ugccaucacc acaauccuga cagcaguaac cuucugcuuc      240

gcauccggac aaaacaucac cgaagaauuu uaccagucaa ccugcuccgc ugucucaaaa      300

ggcuaccucu cagcccuucg caccggcugg uacaccucgg ucauaacaau agaacucucc      360

aauaucaaag aaaacaaaug caacggcacu gacgccaagg uaaaacucau caaacaggaa      420

cucgauaaau acaagaacgc cguaacagaa cuacaacuac ucaugcaauc aacaccggcc      480

accggcuccg guuccgccau augcuccgga guggccgugu gcaagguccu ccaccuugaa      540

ggggaaguua acaaaaucaa aucagcccuc cucuccacua acaaagccgu aguaucccua      600

agcaacggug uauccguccu caccuucaaa guacuagacc uaaagaauua uaucgacaaa      660

caacuccucc ccauacucaa caaacaaucc ugcuccauaa gcaacaucga aacagucauc      720

gaguuccagc agaaaaacaa ccgacuccuc gaaauaaccc gcgaguucuc agucaacgcc      780

ggagucacca cacccgucag caccuacaug cugaccaacu ccgaacuccu cuccuuaauc      840

aaugacaugc ccaucaccaa ugaccaaaag aaacucaugu caaacaacgu ccaaauagua      900

cgccaacaau ccuacuccau caugugcauc auaaaagaag aaguacucgc cuacgucguc      960

caacuccccc ucuacggcgu aaucgacacc cccugcugga aacuacacac aagcccccuc     1020

ugcaccacaa acacuaaaga gggcuccaac aucugucuaa cccgcaccga ucgaggcugg     1080

uacugcgaca acgccggauc ugucucauuc uucccccaag ccgaaaccug caaaguccaa     1140

uccaaccgcg ucuucugcga caccaugaac ucgagaaccc ucccuuccga agucaaccua     1200

ugcaacgucg acauuuucaa ccccaaauac gacugcaaaa ucaugaccuc gaaaaccgac     1260

guaucaucca gcgucaucac cagccuaggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgcga gcaauaaaaa ccgcgggauc aucaaaacuu ucuccaacgg cugcgacuac     1380

gucuccaaca agggagucga uaccgucucc guaggcaaca cccucuacug cgucaacaaa     1440

caagaaggca aaucacuaua cguaaaaggc gagccaauca uaaacuucua cgacccucua     1500

guuuucccau ccgacgaguu cgacgcuagc aucucccaag ucaacgagaa aaucaaccaa     1560

ucccucgcau ucauccgcaa auccgacgaa cuccuccaca acguaaacgc aggcaaauca     1620

acuacuaaua uaaugaucac aaccaucaua auagucauaa ucguaauccu ccuaucccuc     1680

aucgccgucg gacuacugcu cuacugcaaa gcccgcuaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5302
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5302
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucugcagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaaccggggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5303
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5303
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucugcagc ggcguggccg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcg cugcugagca ccaacaaggc cguggucucc      480

cucagcaacg ggguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      540

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcucc cccuguacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggg      960

ugguacugcg acaacgccgg cuccgugagc uucuuccccc aggcggagac cugcaagguc     1020

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1080

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaaccggggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccucua cugcgucaac     1320

aagcaggagg ggaagucccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caagagcgac gagcugcugc acaacgugaa cgcggggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1560

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5304
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5304
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucugcucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaaccgcggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cugcgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5305
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5305
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauauguagc ggaguggcag ucugcaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcc cugcugucca cgaauaaagc uguggucucu      480

cucagcaacg guguguccgu auuaacuuuu aagguucugg accuuaagaa uuacauugau      540

aaacaauugc ugccuauccu aaacaagcag ucauguagua uuagcaauau cgagaccgug      600

auagaguucc agcagaaaaa caauaggcuc cuggaaauua cacgggaguu uucugucaac      660

gccgggguga cuaccccagu guccacauau augcuuacca auucagaacu guugagccuc      720

aucaacgaca ugccgauuac gaacgaucaa aagaaacuga ugaguaauaa cguccagauc      780

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcguaugua      840

gugcaacugc cccucuacgg agucaucgac acuccuuguu ggaaacuuca uacaagccca      900

cugugcacca cuaauacaaa ggagggcucg aacauuuguu ugacccgaac ggaucguggc      960

ugguacugcg acaaugcagg gucugugucc uucuuucccc aggccgaaac cuguaagguu     1020

cagucaaaca gaguguucug cgauacaaug aauaguagaa cucugccuag cgaggucaac     1080

cucugcaaug uggacaucuu uaacccaaaa uaugauugua agauaaugac cuccaaaaca     1140

gacguaucua gcucaguuau uaccagucug ggagcuaucg uguccugcua cgguaagacu     1200

aaauguacag ccagcaauaa gaacaggggc aucauuaaga ccuucucuaa ugggugcgau     1260

uaugucucaa acaaaggagu ggacacuguc agugugggca auacgcuuua cuguguuaac     1320

aagcaagagg guaaaagccu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

uugguauucc cauccgauga guuugacgca ucuauaucgc aggucaauga gaaaaucaac     1440

cagagccucg cuuucauucg gaaguccgau gaacuguuac acaaugugaa cgccggaaag     1500

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1560

cucaucgcgg ucggccugcu uuuguauugc aaagcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5306
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5306
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucugcagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacagaggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cugcgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5307
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5307
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauuuguucc ggcgucgccg ugugcaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcg cuucugucua ccaauaaagc cgucgugucc      480

cucagcaacg gaguuucugu gcugacauuu aagguccuug accugaagaa uuacauugau      540

aaacaacucc ugccuauccu gaacaagcag uccuguagca uuucuaauau cgagaccgug      600

auugaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uuccgugaac      660

gcuggcguca caaccccggu uagcacauau augcuuacca auuccgaacu gcucucucug      720

aucaacgaca ugcccauuac caacgaucaa aagaaacuua ugagcaauaa cgugcagauc      780

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggccuaugug      840

guucaacucc cucuguacgg cgugaucgac acacccuguu ggaaacugca uacgucuccu      900

cucugcacca caaauaccaa ggaggggucc aacaucuguc ugacacggac cgaucgcgga      960

ugguacugcg acaaugcugg cagcgucucu uucuuucccc aggccgaaac guguaaggug     1020

cagagcaaca gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1080

cucugcaaug ucgacauuuu uaacccgaaa uaugauugua agaucaugac cagcaaaaca     1140

gacgugucca gcucugucau uaccucccug ggggcgaucg ugagcugcua cggaaagaca     1200

aaauguacgg ccucuaauaa gaaccggggc auuaucaaga ccuucuccaa ugggugcgau     1260

uauguuagca acaaaggagu ggacacaguc uccgugggca auacccuuua cuguguuaac     1320

aagcaagagg gcaaaucucu guaugugaag ggggaaccca ucauuaacuu uuacgacccu     1380

cucgucuucc ccagcgauga guuugacgcu uccaucucuc aggugaauga gaaaauuaac     1440

cagagccugg ccuucauccg caaguccgau gaacugcucc acaaugugaa cgcuggaaag     1500

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1560

cugaucgccg ugggccuccu gcuguauugc aaagccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5308
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5308
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuuuuaa uacuaaaagc uaacgccaua accacuauac uaacagcagu cacauucugc      120

uucgcaucag gccaaaacau aaccgaagaa uuuuaccaau ccacuuguuc agcagucucc      180

aaaggauauu uauccgcacu ucguacagga ugguauacau caguaauaac aauagaacuc      240

uccaacauaa aagaaaauaa augcaacggc accgacgcaa aaguaaaacu caucaaacaa      300

gaauuagaca aauacaagaa cgccguaaca gaacuacaau uacuaaugca aucaacaccc      360

gccacaggau caggaucugc aauaugcucu ggaguagcag uaugcaaagu auuacaccua      420

gaaggagaag uaaacaaaau caaaagcgca cuacuaucca caaacaaagc uguaguauca      480

cuaucaaacg gaguaucagu auuaacuuuc aaaguacuug aucuaaaaaa cuacauagac      540

aaacaacuac uacccauauu aaacaaacaa ucaugcucaa uaagcaauau agaaacagua      600

auagaauuuc aacaaaaaaa caacagacua cuagaaauca caagggaauu uucaguaaau      660

gccgguguua caaccccagu aucaacauac augcuaacua acucagaacu acuauccuua      720

auaaacgaua ugccaauaac aaacgaucaa aaaaaacuaa uguccaacaa cguacaaaua      780

guaagacaac aaucauacuc aaucaugugc auuauaaaag aagaagucuu agcauacgua      840

guacaauuac cacuauacgg uguaauagau acaccauguu ggaaauuaca cacaagccca      900

cuaugcacaa cuaacacaaa agaaggcuca aauauauguu uaacaagaac agaccgaggu      960

ugguacugcg acaaugcagg aucaguauca uucuuuccac aagcagaaac auguaaaguu     1020

caauccaaca gaguauucug cgacacaaug aacuccagaa cacuaccuuc agaaguaaac     1080

cucuguaacg uagacauauu uaaucccaag uacgacugca aaauaaugac aucgaaaaca     1140

gacguaagcu ccucagugau aacaucccuc ggcgccaucg uauccuguua cgguaaaacu     1200

aaauguaccg ccucaaacaa aaaccgcggu auuauaaaaa cuuuuucuaa uggcugcgau     1260

uacguaagca acaaaggcgu cgacacaguu uccguaggaa acacacuaua cugcguaaac     1320

aaacaagaag guaaaucucu auacguaaaa ggagaaccaa uaauaaauuu cuaugauccu     1380

uuaguauucc cauccgauga auuugacgcc ucuaucucac aagucaacga aaaaauaaau     1440

caaucauuag cauucauacg aaaaucagac gaacuacuac acaacguaaa cgcaggaaaa     1500

ucaacaacca acauaaugau aaccacaaua auaauaguua uuauagugau acuauuaucc     1560

uuaauugcag ucggacuauu auuauacugu aaagcacgcu aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5309
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5309
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccucaaagc caaugccauc accacaaucc ugacagcagu aaccuucugc      120

uucgcauccg gacaaaacau caccgaagaa uuuuaccagu caaccugcuc cgcugucuca      180

aaaggcuacc ucucagcccu ucgcaccggc ugguacaccu cggucauaac aauagaacuc      240

uccaauauca aagaaaacaa augcaacggc acugacgcca agguaaaacu caucaaacag      300

gaacucgaua aauacaagaa cgccguaaca gaacuacaac uacucaugca aucaacaccg      360

gccaccggcu ccgguuccgc cauaugcucc ggaguggccg ugugcaaggu ccuccaccuu      420

gaaggggaag uuaacaaaau caaaucagcc cuccucucca cuaacaaagc cguaguaucc      480

cuaagcaacg guguauccgu ccucaccuuc aaaguacuag accuaaagaa uuauaucgac      540

aaacaacucc uccccauacu caacaaacaa uccugcucca uaagcaacau cgaaacaguc      600

aucgaguucc agcagaaaaa caaccgacuc cucgaaauaa cccgcgaguu cucagucaac      660

gccggaguca ccacacccgu cagcaccuac augcugacca acuccgaacu ccucuccuua      720

aucaaugaca ugcccaucac caaugaccaa aagaaacuca ugucaaacaa cguccaaaua      780

guacgccaac aauccuacuc caucaugugc aucauaaaag aagaaguacu cgccuacguc      840

guccaacucc cccucuacgg cguaaucgac acccccugcu ggaaacuaca cacaagcccc      900

cucugcacca caaacacuaa agagggcucc aacaucuguc uaacccgcac cgaucgaggc      960

ugguacugcg acaacgccgg aucugucuca uucuuccccc aagccgaaac cugcaaaguc     1020

caauccaacc gcgucuucug cgacaccaug aacucgagaa cccucccuuc cgaagucaac     1080

cuaugcaacg ucgacauuuu caaccccaaa uacgacugca aaaucaugac cucgaaaacc     1140

gacguaucau ccagcgucau caccagccua ggcgcaaucg ugagcugcua cggcaaaacc     1200

aaaugcaccg cgagcaauaa aaaccgcggg aucaucaaaa cuuucuccaa cggcugcgac     1260

uacgucucca acaagggagu cgauaccguc uccguaggca acacccucua cugcgucaac     1320

aaacaagaag gcaaaucacu auacguaaaa ggcgagccaa ucauaaacuu cuacgacccu     1380

cuaguuuucc cauccgacga guucgacgcu agcaucuccc aagucaacga gaaaaucaac     1440

caaucccucg cauucauccg caaauccgac gaacuccucc acaacguaaa cgcaggcaaa     1500

ucaacuacua auauaaugau cacaaccauc auaauaguca uaaucguaau ccuccuaucc     1560

cucaucgccg ucggacuacu gcucuacugc aaagcccgcu aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  5310
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5310
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc ugcagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag acggugaucg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugcaga     1020

gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac cgggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacugc gugaacaagc     1320

aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5311
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5311
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccggcagcgg guccgccauc ugcagcggcg uggccgugug caagguccug caccucgagg      420

gcgaggugaa caagaucaag uccgcgcugc ugagcaccaa caaggccgug gucucccuca      480

gcaacggggu guccgugcug acguucaagg uccuggaccu caagaacuac aucgacaagc      540

agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc gugaacgccg      660

gcgucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcucccccu guacggggug aucgacacgc cgugcuggaa gcugcacacc agcccccucu      900

gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac cggggguggu      960

acugcgacaa cgccggcucc gugagcuucu ucccccaggc ggagaccugc aagguccagu     1020

ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag gucaaccugu     1080

gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg aagaccaagu     1200

gcaccgccag caacaagaac cggggcauca ucaagaccuu cuccaacggg ugcgacuacg     1260

ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccucuacugc gucaacaagc     1320

aggaggggaa gucccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcg gggaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc cugagccuga     1560

ucgccguggg ccuccugcug uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5312
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5312
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc ugcuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag accgucaucg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aagguccagu     1020

ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacugc gucaacaagc     1320

aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5313
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5313
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccggcucggg gucagcuaua uguagcggag uggcagucug caagguguug caccucgagg      420

gcgaaguuaa caaaaucaag agugcccugc uguccacgaa uaaagcugug gucucucuca      480

gcaacggugu guccguauua acuuuuaagg uucuggaccu uaagaauuac auugauaaac      540

aauugcugcc uauccuaaac aagcagucau guaguauuag caauaucgag accgugauag      600

aguuccagca gaaaaacaau aggcuccugg aaauuacacg ggaguuuucu gucaacgccg      660

gggugacuac cccagugucc acauauaugc uuaccaauuc agaacuguug agccucauca      720

acgacaugcc gauuacgaac gaucaaaaga aacugaugag uaauaacguc cagaucguuc      780

gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagcg uauguagugc      840

aacugccccu cuacggaguc aucgacacuc cuuguuggaa acuucauaca agcccacugu      900

gcaccacuaa uacaaaggag ggcucgaaca uuuguuugac ccgaacggau cguggcuggu      960

acugcgacaa ugcagggucu guguccuucu uuccccaggc cgaaaccugu aagguucagu     1020

caaacagagu guucugcgau acaaugaaua guagaacucu gccuagcgag gucaaccucu     1080

gcaaugugga caucuuuaac ccaaaauaug auuguaagau aaugaccucc aaaacagacg     1140

uaucuagcuc aguuauuacc agucugggag cuaucguguc cugcuacggu aagacuaaau     1200

guacagccag caauaagaac aggggcauca uuaagaccuu cucuaauggg ugcgauuaug     1260

ucucaaacaa aggaguggac acugucagug ugggcaauac gcuuuacugu guuaacaagc     1320

aagaggguaa aagccuguau gugaaggggg aacccaucau uaacuuuuac gacccuuugg     1380

uauucccauc cgaugaguuu gacgcaucua uaucgcaggu caaugagaaa aucaaccaga     1440

gccucgcuuu cauucggaag uccgaugaac uguuacacaa ugugaacgcc ggaaagucaa     1500

caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug cuaagucuca     1560

ucgcggucgg ccugcuuuug uauugcaaag cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5314
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5314
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc ugcagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag accgugaucg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugcaga     1020

gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac agaggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacugc gugaacaagc     1320

aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5315
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5315
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

cagggucugg aagcgcuauu uguuccggcg ucgccgugug caagguucuc caccuggagg      420

gggaagugaa caaaaucaag agcgcgcuuc ugucuaccaa uaaagccguc gugucccuca      480

gcaacggagu uucugugcug acauuuaagg uccuugaccu gaagaauuac auugauaaac      540

aacuccugcc uauccugaac aagcaguccu guagcauuuc uaauaucgag accgugauug      600

aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuucc gugaacgcug      660

gcgucacaac cccgguuagc acauauaugc uuaccaauuc cgaacugcuc ucucugauca      720

acgacaugcc cauuaccaac gaucaaaaga aacuuaugag caauaacgug cagaucguga      780

gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcc uaugugguuc      840

aacucccucu guacggcgug aucgacacac ccuguuggaa acugcauacg ucuccucucu      900

gcaccacaaa uaccaaggag ggguccaaca ucugucugac acggaccgau cgcggauggu      960

acugcgacaa ugcuggcagc gucucuuucu uuccccaggc cgaaacgugu aaggugcaga     1020

gcaacagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag gugaaucucu     1080

gcaaugucga cauuuuuaac ccgaaauaug auuguaagau caugaccagc aaaacagacg     1140

uguccagcuc ugucauuacc ucccuggggg cgaucgugag cugcuacgga aagacaaaau     1200

guacggccuc uaauaagaac cggggcauua ucaagaccuu cuccaauggg ugcgauuaug     1260

uuagcaacaa aggaguggac acagucuccg ugggcaauac ccuuuacugu guuaacaagc     1320

aagagggcaa aucucuguau gugaaggggg aacccaucau uaacuuuuac gacccucucg     1380

ucuuccccag cgaugaguuu gacgcuucca ucucucaggu gaaugagaaa auuaaccaga     1440

gccuggccuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcu ggaaagagca     1500

caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug cuuucucuga     1560

ucgccguggg ccuccugcug uauugcaaag ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5316
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5316
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uuuuaauacu aaaagcuaac gccauaacca cuauacuaac agcagucaca uucugcuucg      120

caucaggcca aaacauaacc gaagaauuuu accaauccac uuguucagca gucuccaaag      180

gauauuuauc cgcacuucgu acaggauggu auacaucagu aauaacaaua gaacucucca      240

acauaaaaga aaauaaaugc aacggcaccg acgcaaaagu aaaacucauc aaacaagaau      300

uagacaaaua caagaacgcc guaacagaac uacaauuacu aaugcaauca acacccgcca      360

caggaucagg aucugcaaua ugcucuggag uagcaguaug caaaguauua caccuagaag      420

gagaaguaaa caaaaucaaa agcgcacuac uauccacaaa caaagcugua guaucacuau      480

caaacggagu aucaguauua acuuucaaag uacuugaucu aaaaaacuac auagacaaac      540

aacuacuacc cauauuaaac aaacaaucau gcucaauaag caauauagaa acaguaauag      600

aauuucaaca aaaaaacaac agacuacuag aaaucacaag ggaauuuuca guaaaugccg      660

guguuacaac cccaguauca acauacaugc uaacuaacuc agaacuacua uccuuaauaa      720

acgauaugcc aauaacaaac gaucaaaaaa aacuaauguc caacaacgua caaauaguaa      780

gacaacaauc auacucaauc augugcauua uaaaagaaga agucuuagca uacguaguac      840

aauuaccacu auacggugua auagauacac cauguuggaa auuacacaca agcccacuau      900

gcacaacuaa cacaaaagaa ggcucaaaua uauguuuaac aagaacagac cgagguuggu      960

acugcgacaa ugcaggauca guaucauucu uuccacaagc agaaacaugu aaaguucaau     1020

ccaacagagu auucugcgac acaaugaacu ccagaacacu accuucagaa guaaaccucu     1080

guaacguaga cauauuuaau cccaaguacg acugcaaaau aaugacaucg aaaacagacg     1140

uaagcuccuc agugauaaca ucccucggcg ccaucguauc cuguuacggu aaaacuaaau     1200

guaccgccuc aaacaaaaac cgcgguauua uaaaaacuuu uucuaauggc ugcgauuacg     1260

uaagcaacaa aggcgucgac acaguuuccg uaggaaacac acuauacugc guaaacaaac     1320

aagaagguaa aucucuauac guaaaaggag aaccaauaau aaauuucuau gauccuuuag     1380

uauucccauc cgaugaauuu gacgccucua ucucacaagu caacgaaaaa auaaaucaau     1440

cauuagcauu cauacgaaaa ucagacgaac uacuacacaa cguaaacgca ggaaaaucaa     1500

caaccaacau aaugauaacc acaauaauaa uaguuauuau agugauacua uuauccuuaa     1560

uugcagucgg acuauuauua uacuguaaag cacgcuaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5317
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5317
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu caaagccaau gccaucacca caauccugac agcaguaacc uucugcuucg      120

cauccggaca aaacaucacc gaagaauuuu accagucaac cugcuccgcu gucucaaaag      180

gcuaccucuc agcccuucgc accggcuggu acaccucggu cauaacaaua gaacucucca      240

auaucaaaga aaacaaaugc aacggcacug acgccaaggu aaaacucauc aaacaggaac      300

ucgauaaaua caagaacgcc guaacagaac uacaacuacu caugcaauca acaccggcca      360

ccggcuccgg uuccgccaua ugcuccggag uggccgugug caagguccuc caccuugaag      420

gggaaguuaa caaaaucaaa ucagcccucc ucuccacuaa caaagccgua guaucccuaa      480

gcaacggugu auccguccuc accuucaaag uacuagaccu aaagaauuau aucgacaaac      540

aacuccuccc cauacucaac aaacaauccu gcuccauaag caacaucgaa acagucaucg      600

aguuccagca gaaaaacaac cgacuccucg aaauaacccg cgaguucuca gucaacgccg      660

gagucaccac acccgucagc accuacaugc ugaccaacuc cgaacuccuc uccuuaauca      720

augacaugcc caucaccaau gaccaaaaga aacucauguc aaacaacguc caaauaguac      780

gccaacaauc cuacuccauc augugcauca uaaaagaaga aguacucgcc uacgucgucc      840

aacucccccu cuacggcgua aucgacaccc ccugcuggaa acuacacaca agcccccucu      900

gcaccacaaa cacuaaagag ggcuccaaca ucugucuaac ccgcaccgau cgaggcuggu      960

acugcgacaa cgccggaucu gucucauucu ucccccaagc cgaaaccugc aaaguccaau     1020

ccaaccgcgu cuucugcgac accaugaacu cgagaacccu cccuuccgaa gucaaccuau     1080

gcaacgucga cauuuucaac cccaaauacg acugcaaaau caugaccucg aaaaccgacg     1140

uaucauccag cgucaucacc agccuaggcg caaucgugag cugcuacggc aaaaccaaau     1200

gcaccgcgag caauaaaaac cgcgggauca ucaaaacuuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggagucgau accgucuccg uaggcaacac ccucuacugc gucaacaaac     1320

aagaaggcaa aucacuauac guaaaaggcg agccaaucau aaacuucuac gacccucuag     1380

uuuucccauc cgacgaguuc gacgcuagca ucucccaagu caacgagaaa aucaaccaau     1440

cccucgcauu cauccgcaaa uccgacgaac uccuccacaa cguaaacgca ggcaaaucaa     1500

cuacuaauau aaugaucaca accaucauaa uagucauaau cguaauccuc cuaucccuca     1560

ucgccgucgg acuacugcuc uacugcaaag cccgcuaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  5318
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1) R7459

<400>  5318
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucugcagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

agcaacaucg agacggugau cgaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugca gagcaaccgc guguucugcg acaccaugaa cucccggacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga accgggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu gcgugaacaa gcaggagggc aagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5319
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt1)

<400>  5319
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccggcagc ggguccgcca ucugcagcgg cguggccgug      360

ugcaaggucc ugcaccucga gggcgaggug aacaagauca aguccgcgcu gcugagcacc      420

aacaaggccg uggucucccu cagcaacggg guguccgugc ugacguucaa gguccuggac      480

cucaagaacu acaucgacaa gcagcugcug ccgauccuca acaagcagag cugcuccauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca accggcugcu ggagaucacc      600

cgcgaguucu ccgugaacgc cggcgucacc acgcccguga gcaccuacau gcucaccaac      660

agcgagcugc ugucccucau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcucccc cuguacgggg ugaucgacac gccgugcugg      840

aagcugcaca ccagcccccu cugcaccacc aacacgaagg agggcuccaa caucugccug      900

acccgcaccg accgggggug guacugcgac aacgccggcu ccgugagcuu cuucccccag      960

gcggagaccu gcaaggucca guccaaccgc guguucugcg acacgaugaa cagccggacc     1020

cuccccuccg aggucaaccu gugcaacgug gacaucuuca acccgaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg cgccaucgug     1140

uccugcuacg ggaagaccaa gugcaccgcc agcaacaaga accggggcau caucaagacc     1200

uucuccaacg ggugcgacua cgugagcaac aagggcgucg acacggugag cgugggcaac     1260

acccucuacu gcgucaacaa gcaggagggg aagucccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca agagcgacga gcugcugcac     1440

aacgugaacg cggggaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc uccugagccu gaucgccgug ggccuccugc uguacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5320
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt2)

<400>  5320
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucugcuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

uccaacaucg agaccgucau cgaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucca guccaaccgc gucuucugcg acaccaugaa cucccgcacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga accgcggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu gcgucaacaa gcaggagggc aagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5321
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt3)

<400>  5321
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccggcucg gggucagcua uauguagcgg aguggcaguc      360

ugcaaggugu ugcaccucga gggcgaaguu aacaaaauca agagugcccu gcuguccacg      420

aauaaagcug uggucucucu cagcaacggu guguccguau uaacuuuuaa gguucuggac      480

cuuaagaauu acauugauaa acaauugcug ccuauccuaa acaagcaguc auguaguauu      540

agcaauaucg agaccgugau agaguuccag cagaaaaaca auaggcuccu ggaaauuaca      600

cgggaguuuu cugucaacgc cggggugacu accccagugu ccacauauau gcuuaccaau      660

ucagaacugu ugagccucau caacgacaug ccgauuacga acgaucaaaa gaaacugaug      720

aguaauaacg uccagaucgu ucgccagcag ucuuacucca ucaugugcau uauaaaggag      780

gaaguguuag cguauguagu gcaacugccc cucuacggag ucaucgacac uccuuguugg      840

aaacuucaua caagcccacu gugcaccacu aauacaaagg agggcucgaa cauuuguuug      900

acccgaacgg aucguggcug guacugcgac aaugcagggu cuguguccuu cuuuccccag      960

gccgaaaccu guaagguuca gucaaacaga guguucugcg auacaaugaa uaguagaacu     1020

cugccuagcg aggucaaccu cugcaaugug gacaucuuua acccaaaaua ugauuguaag     1080

auaaugaccu ccaaaacaga cguaucuagc ucaguuauua ccagucuggg agcuaucgug     1140

uccugcuacg guaagacuaa auguacagcc agcaauaaga acaggggcau cauuaagacc     1200

uucucuaaug ggugcgauua ugucucaaac aaaggagugg acacugucag ugugggcaau     1260

acgcuuuacu guguuaacaa gcaagagggu aaaagccugu augugaaggg ggaacccauc     1320

auuaacuuuu acgacccuuu gguauuccca uccgaugagu uugacgcauc uauaucgcag     1380

gucaaugaga aaaucaacca gagccucgcu uucauucgga aguccgauga acuguuacac     1440

aaugugaacg ccggaaaguc aacaaccaau aucaugauca cuaccauuau aaucguuauu     1500

aucgugauuc ugcuaagucu caucgcgguc ggccugcuuu uguauugcaa agcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5322
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt4)

<400>  5322
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucugcagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

agcaacaucg agaccgugau cgaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugca gagcaacaga guguucugcg acaccaugaa cagcagaacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acagaggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu gcgugaacaa gcaggagggc aagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5323
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt5)

<400>  5323
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacagggucu ggaagcgcua uuuguuccgg cgucgccgug      360

ugcaagguuc uccaccugga gggggaagug aacaaaauca agagcgcgcu ucugucuacc      420

aauaaagccg ucgugucccu cagcaacgga guuucugugc ugacauuuaa gguccuugac      480

cugaagaauu acauugauaa acaacuccug ccuauccuga acaagcaguc cuguagcauu      540

ucuaauaucg agaccgugau ugaguuccag cagaaaaaca aucggcuccu ggaaaucacg      600

cgcgaguuuu ccgugaacgc uggcgucaca accccgguua gcacauauau gcuuaccaau      660

uccgaacugc ucucucugau caacgacaug cccauuacca acgaucaaaa gaaacuuaug      720

agcaauaacg ugcagaucgu gagacagcag uccuacagca uuaugugcau cauuaaggag      780

gaaguccugg ccuauguggu ucaacucccu cuguacggcg ugaucgacac acccuguugg      840

aaacugcaua cgucuccucu cugcaccaca aauaccaagg agggguccaa caucugucug      900

acacggaccg aucgcggaug guacugcgac aaugcuggca gcgucucuuu cuuuccccag      960

gccgaaacgu guaaggugca gagcaacaga guuuucugcg auacaaugaa cuccagaacc     1020

cugccuucug aggugaaucu cugcaauguc gacauuuuua acccgaaaua ugauuguaag     1080

aucaugacca gcaaaacaga cguguccagc ucugucauua ccucccuggg ggcgaucgug     1140

agcugcuacg gaaagacaaa auguacggcc ucuaauaaga accggggcau uaucaagacc     1200

uucuccaaug ggugcgauua uguuagcaac aaaggagugg acacagucuc cgugggcaau     1260

acccuuuacu guguuaacaa gcaagagggc aaaucucugu augugaaggg ggaacccauc     1320

auuaacuuuu acgacccucu cgucuucccc agcgaugagu uugacgcuuc caucucucag     1380

gugaaugaga aaauuaacca gagccuggcc uucauccgca aguccgauga acugcuccac     1440

aaugugaacg cuggaaagag cacaaccaau auuaugauca cgaccauuau caucguuauu     1500

aucgucauuc ugcuuucucu gaucgccgug ggccuccugc uguauugcaa agccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5324
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt6)

<400>  5324
gggagaaagc uuaccaugga acuuuuaaua cuaaaagcua acgccauaac cacuauacua       60

acagcaguca cauucugcuu cgcaucaggc caaaacauaa ccgaagaauu uuaccaaucc      120

acuuguucag cagucuccaa aggauauuua uccgcacuuc guacaggaug guauacauca      180

guaauaacaa uagaacucuc caacauaaaa gaaaauaaau gcaacggcac cgacgcaaaa      240

guaaaacuca ucaaacaaga auuagacaaa uacaagaacg ccguaacaga acuacaauua      300

cuaaugcaau caacacccgc cacaggauca ggaucugcaa uaugcucugg aguagcagua      360

ugcaaaguau uacaccuaga aggagaagua aacaaaauca aaagcgcacu acuauccaca      420

aacaaagcug uaguaucacu aucaaacgga guaucaguau uaacuuucaa aguacuugau      480

cuaaaaaacu acauagacaa acaacuacua cccauauuaa acaaacaauc augcucaaua      540

agcaauauag aaacaguaau agaauuucaa caaaaaaaca acagacuacu agaaaucaca      600

agggaauuuu caguaaaugc cgguguuaca accccaguau caacauacau gcuaacuaac      660

ucagaacuac uauccuuaau aaacgauaug ccaauaacaa acgaucaaaa aaaacuaaug      720

uccaacaacg uacaaauagu aagacaacaa ucauacucaa ucaugugcau uauaaaagaa      780

gaagucuuag cauacguagu acaauuacca cuauacggug uaauagauac accauguugg      840

aaauuacaca caagcccacu augcacaacu aacacaaaag aaggcucaaa uauauguuua      900

acaagaacag accgagguug guacugcgac aaugcaggau caguaucauu cuuuccacaa      960

gcagaaacau guaaaguuca auccaacaga guauucugcg acacaaugaa cuccagaaca     1020

cuaccuucag aaguaaaccu cuguaacgua gacauauuua aucccaagua cgacugcaaa     1080

auaaugacau cgaaaacaga cguaagcucc ucagugauaa caucccucgg cgccaucgua     1140

uccuguuacg guaaaacuaa auguaccgcc ucaaacaaaa accgcgguau uauaaaaacu     1200

uuuucuaaug gcugcgauua cguaagcaac aaaggcgucg acacaguuuc cguaggaaac     1260

acacuauacu gcguaaacaa acaagaaggu aaaucucuau acguaaaagg agaaccaaua     1320

auaaauuucu augauccuuu aguauuccca uccgaugaau uugacgccuc uaucucacaa     1380

gucaacgaaa aaauaaauca aucauuagca uucauacgaa aaucagacga acuacuacac     1440

aacguaaacg caggaaaauc aacaaccaac auaaugauaa ccacaauaau aauaguuauu     1500

auagugauac uauuauccuu aauugcaguc ggacuauuau uauacuguaa agcacgcuaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5325
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut4 (opt11)

<400>  5325
gggagaaagc uuaccaugga acuccucauc cucaaagcca augccaucac cacaauccug       60

acagcaguaa ccuucugcuu cgcauccgga caaaacauca ccgaagaauu uuaccaguca      120

accugcuccg cugucucaaa aggcuaccuc ucagcccuuc gcaccggcug guacaccucg      180

gucauaacaa uagaacucuc caauaucaaa gaaaacaaau gcaacggcac ugacgccaag      240

guaaaacuca ucaaacagga acucgauaaa uacaagaacg ccguaacaga acuacaacua      300

cucaugcaau caacaccggc caccggcucc gguuccgcca uaugcuccgg aguggccgug      360

ugcaaggucc uccaccuuga aggggaaguu aacaaaauca aaucagcccu ccucuccacu      420

aacaaagccg uaguaucccu aagcaacggu guauccgucc ucaccuucaa aguacuagac      480

cuaaagaauu auaucgacaa acaacuccuc cccauacuca acaaacaauc cugcuccaua      540

agcaacaucg aaacagucau cgaguuccag cagaaaaaca accgacuccu cgaaauaacc      600

cgcgaguucu cagucaacgc cggagucacc acacccguca gcaccuacau gcugaccaac      660

uccgaacucc ucuccuuaau caaugacaug cccaucacca augaccaaaa gaaacucaug      720

ucaaacaacg uccaaauagu acgccaacaa uccuacucca ucaugugcau cauaaaagaa      780

gaaguacucg ccuacgucgu ccaacucccc cucuacggcg uaaucgacac ccccugcugg      840

aaacuacaca caagcccccu cugcaccaca aacacuaaag agggcuccaa caucugucua      900

acccgcaccg aucgaggcug guacugcgac aacgccggau cugucucauu cuucccccaa      960

gccgaaaccu gcaaagucca auccaaccgc gucuucugcg acaccaugaa cucgagaacc     1020

cucccuuccg aagucaaccu augcaacguc gacauuuuca accccaaaua cgacugcaaa     1080

aucaugaccu cgaaaaccga cguaucaucc agcgucauca ccagccuagg cgcaaucgug     1140

agcugcuacg gcaaaaccaa augcaccgcg agcaauaaaa accgcgggau caucaaaacu     1200

uucuccaacg gcugcgacua cgucuccaac aagggagucg auaccgucuc cguaggcaac     1260

acccucuacu gcgucaacaa acaagaaggc aaaucacuau acguaaaagg cgagccaauc     1320

auaaacuucu acgacccucu aguuuuccca uccgacgagu ucgacgcuag caucucccaa     1380

gucaacgaga aaaucaacca aucccucgca uucauccgca aauccgacga acuccuccac     1440

aacguaaacg caggcaaauc aacuacuaau auaaugauca caaccaucau aauagucaua     1500

aucguaaucc uccuaucccu caucgccguc ggacuacugc ucuacugcaa agcccgcuaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  5326
<211>  536
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5326

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Gly 
    130                 135                 140                 


Cys Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr 
145                 150                 155                 160 


Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile 
                165                 170                 175     


Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu 
            180                 185                 190         


Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro 
        195                 200                 205             


Val Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn 
    210                 215                 220                 


Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val 
225                 230                 235                 240 


Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu 
                245                 250                 255     


Glu Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp 
            260                 265                 270         


Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr 
        275                 280                 285             


Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr 
    290                 295                 300                 


Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys 
305                 310                 315                 320 


Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Arg Thr 
                325                 330                 335     


Leu Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys 
            340                 345                 350         


Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val 
        355                 360                 365             


Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys 
    370                 375                 380                 


Thr Ala Ser Asn Lys Cys Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly 
385                 390                 395                 400 


Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn 
                405                 410                 415     


Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys 
            420                 425                 430         


Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp 
        435                 440                 445             


Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser 
    450                 455                 460                 


Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala 
465                 470                 475                 480 


Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile 
                485                 490                 495     


Ile Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys 
            500                 505                 510         


Lys Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly 
        515                 520                 525             


Ile Asn Asn Ile Ala Phe Ser Asn 
    530                 535     


<210>  5327
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5327
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucuccg gcugcggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      540

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      600

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      660

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      780

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      840

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac      900

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc      960

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1020

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1140

aagacgaagu gcaccgccag caacaagugc cgggggauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1260

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1320

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1380

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1440

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1500

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1560

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug a              1611


<210>  5328
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5328
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccaccg gcagcggguc cgccaucgcc agcggcgugg cggugugcaa gguccugcac      360

cucgagggcg aggugaacaa gaucaagucc gcccugcuga gcaccaacaa ggccgugguc      420

ucccucagcg ggugcggcgu guccgugcug acguucaagg uccuggaccu caagaacuac      480

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      540

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      600

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      660

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggucc agcucccccu guacggcgug aucgacacgc cgugcuggaa gcugcacacc      840

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac      900

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1020

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1080

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1140

aagaccaagu gcaccgccag caacaagugc cgggggauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg uggggaacac ccucuacuac     1260

gucaacaagc aggagggcaa gucccuguac gugaaggggg agcccaucau caacuucuac     1320

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1380

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1440

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1500

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguccac cccggugacc     1560

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug a              1611


<210>  5329
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5329
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucuccg gcugcggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      480

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      540

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      600

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      660

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      720

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      780

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      840

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac      900

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1020

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1140

aagaccaagu gcaccgccuc caacaagugc cgcggcauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1260

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1320

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1380

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1440

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1500

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1560

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug a              1611


<210>  5330
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5330
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccaccg gcucgggguc agcuauagca agcggagugg ccgucuguaa gguguugcac      360

cucgagggcg aaguuaacaa aaucaagagu gcucugcugu ccacgaauaa agccgugguc      420

ucucucagcg guugcggggu guccguauua acuuuuaagg uucuggaccu uaagaacuac      480

auugauaaac aauugcugcc uauccuaaau aagcagucau guaguauuag caacaucgag      540

accgugauag aguuccagca gaaaaauaac aggcuccugg aaauuacacg ggaguuuucu      600

gucaaugcgg gagugacuac cccagugucc acauauaugc uuaccaacuc agaacuguug      660

agccucauca augacaugcc gauuacgaac gaucaaaaga aacugaugag uaacaauguc      720

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagca      780

uauguagugc aacugccccu cuacggcguc aucgacacuc cuuguuggaa acuucauaca      840

agcccacugu gcaccacuaa cacaaaggag ggcucgaaua uuuguuugac ccgaacggau      900

cguggguggu acugcgacaa cgccggaucu guguccuucu uuccccaggc ugaaaccugu      960

aagguucagu caaauagagu guucugcgau acaaugaaca guagaacucu gccuagcgag     1020

gucaaucucu gcaacgugga caucuuuaau ccaaaauaug auuguaagau aaugaccucc     1080

aaaacagacg uaucuagcuc aguuauuacc agucugggug ccaucguguc cugcuacggc     1140

aagacuaaau guacagcaag caacaagugc agggggauca uuaagaccuu cucuaaugga     1200

ugugauuaug ucucaaacaa aggcguggac acugucagug uggguaauac gcuuuacuau     1260

guuaacaagc aagaggggaa aagccuguac gugaagggag aacccaucau uaauuuuuau     1320

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caacgagaaa     1380

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1440

ggcaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1500

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcucuac accggugacc     1560

cugagcaagg accagcucuc cgggauaaac aauaucgcuu ucucaaacug a              1611


<210>  5331
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5331
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagcg gcugcggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      540

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      600

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      660

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      840

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac      900

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc      960

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1020

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1080

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1140

aagaccaagu gcaccgccag caacaagugc agaggcauca ucaagaccuu cagcaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1260

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1320

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1380

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1440

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1500

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1560

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug a              1611


<210>  5332
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5332
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacag ggucuggaag cgcuauugcc uccggcgucg cgguguguaa gguucuccac      360

cuggaggggg aagugaacaa aaucaagagc gcccuucugu cuaccaauaa agcugucgug      420

ucccucagcg gaugcggcgu uucugugcug acauuuaagg uccuugaccu gaagaacuac      480

auugauaaac aacuccugcc uauccugaau aagcaguccu guagcauuuc uaacaucgag      540

accgugauug aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuucc      600

gugaaugccg gcgucacaac cccgguuagc acauauaugc uuaccaacuc cgaacugcuc      660

ucucugauca augacaugcc cauuaccaac gaucaaaaga aacuuaugag caacaaugug      720

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcu      780

uaugugguuc aacucccucu guacggggug aucgacacac ccuguuggaa acugcauacg      840

ucuccucucu gcaccacaaa caccaaggag ggauccaaua ucugucugac acggaccgau      900

cgcggcuggu acugcgacaa cgccgggagc gucucuuucu uuccccaggc ggaaacgugu      960

aaggugcaga gcaauagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1020

gugaaucucu gcaacgucga cauuuuuaau ccgaaauaug auuguaagau caugaccagc     1080

aaaacagacg uguccagcuc ugucauuacc ucccugggag ccaucgugag cugcuacggc     1140

aagacaaaau guacggcuuc uaacaagugc cgggggauua ucaagaccuu cuccaaugga     1200

ugugauuaug uuagcaacaa aggcguggac acagucuccg ugggcaauac ccuuuacuau     1260

guuaacaagc aagaggggaa aucucuguac gugaagggag aacccaucau uaauuuuuau     1320

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaacgagaaa     1380

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1440

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1500

cuuucucuga ucgccguggg gcuccugcug uacugcaaag cuagauccac accugugacc     1560

cuuagcaagg accagcucuc uggaauuaac aauaucgcgu ucuccaacug a              1611


<210>  5333
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5333
auggaacuau uaauacuuaa agccaacgca auaacaacaa uucucacugc ugucaccuuc       60

ugcuucgccu caggccaaaa cauaacggaa gaauuuuacc aaucaacaug cucugcagua      120

uccaaaggcu accuaucugc ucuaagaaca gguugguaua caucaguaau aaccauagaa      180

cuaucaaaca uaaaagaaaa uaaaugcaac ggaacagacg caaaaguuaa acucauaaaa      240

caagaacuag acaaauauaa aaacgcaguu accgaacuac aacuacuuau gcaauccacu      300

cccgccacug gaucaggauc agcaauagca ucaggagucg caguauguaa agucuuacac      360

cucgaaggcg aagucaauaa aaucaaaucc gcauuacuau ccacaaacaa agcagucgua      420

ucccuaagcg gaugcggagu aucaguacua acauuuaaag uacuagaccu aaaaaauuac      480

aucgauaaac aacuauuacc uauauuaaac aaacaauccu gcuccauuuc aaauaucgaa      540

accguaauag aauuucaaca aaaaaacaac agauuacuag aaauaacaag agaauuuucc      600

guaaaugcug gcguaacaac accaguaucc acauacaugc ucacaaacuc cgaacuacua      660

ucacuaauaa augacaugcc cauaacaaac gaucaaaaaa aacuaauguc aaauaaugua      720

caaauaguaa gacaacaaag cuacuccauc auguguauaa uaaaagaaga aguacuagca      780

uacguaguuc aacuaccacu uuacggcgua aucgacaccc cuugcuggaa acuacacacc      840

uccccucuau gcaccacaaa cacaaaagaa gguuccaaca uaugccuuac cagaacagac      900

agaggcuggu auugcgacaa cgcaggauca guuucauuuu uuccacaagc ugaaacaugc      960

aaaguacaau caaacagagu cuucugcgac acaaugaacu caagaacucu acccucagaa     1020

guaaaccuau guaacguaga cauuuucaac cccaaauacg acugcaaaau uaugacauca     1080

aaaacagacg uuucaucauc aguuaucacc ucauuaggag caauaguaag cugcuacgga     1140

aaaacaaaau gcaccgccuc aaauaaaugc agaggaauaa uaaaaacuuu cuccaacgga     1200

ugcgacuacg uuucaaacaa agguguagac acuguaucag uaggaaacac acuauauuac     1260

guaaauaaac aagaaggaaa aucacuuuau gucaaaggag aaccaauaau caauuucuac     1320

gacccauuag uauucccauc agacgaauuu gaugcuucaa uaucacaagu aaacgaaaaa     1380

auaaaucaau cacucgcauu uauacgaaaa ucagacgaac uacuacacaa uguaaacgca     1440

ggcaaaucaa caacaaacau aaugauaaca acaauaauca uuguaauaau aguaauacuu     1500

cuaucucuaa uagcaguagg auuacuccuc uacugcaaag caagaucaac cccuguaaca     1560

cuaucaaaag accaacuuuc agguauaaau aauauagcuu uuuccaauua a              1611


<210>  5334
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut5

<400>  5334
auggagcucc uaauccucaa agccaacgcg aucacuacaa uccucacagc cgucaccuuc       60

ugcuucgccu ccggccaaaa caucaccgag gaguucuacc aaucaaccug cuccgccgua      120

ucaaaaggau accuaagcgc ccuacggacc ggcugguaca caucugucau caccaucgaa      180

cuaucaaaca ucaaagaaaa caaaugcaac ggaaccgacg caaaagucaa acugauuaaa      240

caagaacuag acaaauacaa aaacgcaguc accgaacugc aauuacucau gcaaagcaca      300

ccggccaccg gcucaggcag cgccaucgcc uccggcgucg ccgucugcaa aguucuccac      360

cucgagggcg aagucaacaa aauaaaaucu gcccuccucu ccaccaacaa agccgucguc      420

ucccucagcg gcugcggagu cuccguccuc accuucaaag uucucgaucu caagaacuau      480

auugacaaac aacuucuacc cauacucaac aaacaaagcu gcagcauauc caacaucgaa      540

accgucaucg aguuccaaca aaagaacaac cgccuccucg aaauaacccg cgaguucagc      600

guuaacgccg gagucacuac cccugucucc accuacaugc ucaccaacuc cgaacuccua      660

ucacuaauca acgacaugcc cauaaccaac gaccagaaga aacucauguc caacaacguc      720

caaauugucc gacaacaaag cuacuccaua augugcauaa uaaaagagga aguccucgcc      780

uacgucguac aacugccccu uuauggcgua aucgacacac ccugcuggaa acuccacacg      840

ucaccccucu gcaccaccaa cacaaaagaa ggcucgaaca ucugccuaac acggacugac      900

cgcggcuggu acugcgacaa cgccggcucc gucagcuucu ucccacaagc cgaaaccugc      960

aaaguacaau ccaaccgagu auucugcgac accaugaacu ccagaacccu ccccucagag     1020

gucaaccugu gcaacguaga caucuucaac cccaaauacg acugcaaaau aaugaccuca     1080

aaaacagacg ucuccucuuc cguaaucacc agccucggag ccaucgucag cugcuacggc     1140

aaaaccaaau gcaccgccuc aaacaaaugc cgcggcauca ucaaaacauu cucaaacggc     1200

ugcgacuacg ucuccaacaa aggcgucgac acaguaagcg uaggcaacac acuguacuac     1260

gucaacaaac aagagggaaa aucacucuac gucaaaggag aacccauaau caacuucuac     1320

gacccccucg uuuuccccag cgacgaguuc gacgccagca uaucccaagu caacgagaaa     1380

auuaaccaau cccuagcauu cauccgaaaa ucugacgaac ugcuccacaa cgucaacgcg     1440

ggaaaaucaa caaccaacau aaugauaacc acaaucauaa uagucaucau cguaauccuc     1500

cucagccuaa ucgcugucgg ccuccuccuc uacugcaaag cccguuccac cccagucaca     1560

cuuuccaagg accaacuaag cggaauaaac aacaucgcgu ucucaaacua a              1611


<210>  5335
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5335
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5336
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5336
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

gguccacccc ggugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5337
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5337
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5338
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5338
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcucuacacc ggugacccug agcaaggacc agcucuccgg gauaaacaau aucgcuuucu     1680

caaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5339
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5339
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5340
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5340
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gauccacacc ugugacccuu agcaaggacc agcucucugg aauuaacaau aucgcguucu     1680

ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5341
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5341
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc      120

ucacugcugu caccuucugc uucgccucag gccaaaacau aacggaagaa uuuuaccaau      180

caacaugcuc ugcaguaucc aaaggcuacc uaucugcucu aagaacaggu ugguauacau      240

caguaauaac cauagaacua ucaaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguuaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac      360

uacuuaugca auccacuccc gccacuggau caggaucagc aauagcauca ggagucgcag      420

uauguaaagu cuuacaccuc gaaggcgaag ucaauaaaau caaauccgca uuacuaucca      480

caaacaaagc agucguaucc cuaagcggau gcggaguauc aguacuaaca uuuaaaguac      540

uagaccuaaa aaauuacauc gauaaacaac uauuaccuau auuaaacaaa caauccugcu      600

ccauuucaaa uaucgaaacc guaauagaau uucaacaaaa aaacaacaga uuacuagaaa      660

uaacaagaga auuuuccgua aaugcuggcg uaacaacacc aguauccaca uacaugcuca      720

caaacuccga acuacuauca cuaauaaaug acaugcccau aacaaacgau caaaaaaaac      780

uaaugucaaa uaauguacaa auaguaagac aacaaagcua cuccaucaug uguauaauaa      840

aagaagaagu acuagcauac guaguucaac uaccacuuua cggcguaauc gacaccccuu      900

gcuggaaacu acacaccucc ccucuaugca ccacaaacac aaaagaaggu uccaacauau      960

gccuuaccag aacagacaga ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc     1020

cacaagcuga aacaugcaaa guacaaucaa acagagucuu cugcgacaca augaacucaa     1080

gaacucuacc cucagaagua aaccuaugua acguagacau uuucaacccc aaauacgacu     1140

gcaaaauuau gacaucaaaa acagacguuu caucaucagu uaucaccuca uuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa     1260

aaacuuucuc caacggaugc gacuacguuu caaacaaagg uguagacacu guaucaguag     1320

gaaacacacu auauuacgua aauaaacaag aaggaaaauc acuuuauguc aaaggagaac     1380

caauaaucaa uuucuacgac ccauuaguau ucccaucaga cgaauuugau gcuucaauau     1440

cacaaguaaa cgaaaaaaua aaucaaucac ucgcauuuau acgaaaauca gacgaacuac     1500

uacacaaugu aaacgcaggc aaaucaacaa caaacauaau gauaacaaca auaaucauug     1560

uaauaauagu aauacuucua ucucuaauag caguaggauu acuccucuac ugcaaagcaa     1620

gaucaacccc uguaacacua ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu     1680

ccaauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5342
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5342
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuaa uccucaaagc caacgcgauc acuacaaucc      120

ucacagccgu caccuucugc uucgccuccg gccaaaacau caccgaggag uucuaccaau      180

caaccugcuc cgccguauca aaaggauacc uaagcgcccu acggaccggc ugguacacau      240

cugucaucac caucgaacua ucaaacauca aagaaaacaa augcaacgga accgacgcaa      300

aagucaaacu gauuaaacaa gaacuagaca aauacaaaaa cgcagucacc gaacugcaau      360

uacucaugca aagcacaccg gccaccggcu caggcagcgc caucgccucc ggcgucgccg      420

ucugcaaagu ucuccaccuc gagggcgaag ucaacaaaau aaaaucugcc cuccucucca      480

ccaacaaagc cgucgucucc cucagcggcu gcggagucuc cguccucacc uucaaaguuc      540

ucgaucucaa gaacuauauu gacaaacaac uucuacccau acucaacaaa caaagcugca      600

gcauauccaa caucgaaacc gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

uaacccgcga guucagcguu aacgccggag ucacuacccc ugucuccacc uacaugcuca      720

ccaacuccga acuccuauca cuaaucaacg acaugcccau aaccaacgac cagaagaaac      780

ucauguccaa caacguccaa auuguccgac aacaaagcua cuccauaaug ugcauaauaa      840

aagaggaagu ccucgccuac gucguacaac ugccccuuua uggcguaauc gacacacccu      900

gcuggaaacu ccacacguca ccccucugca ccaccaacac aaaagaaggc ucgaacaucu      960

gccuaacacg gacugaccgc ggcugguacu gcgacaacgc cggcuccguc agcuucuucc     1020

cacaagccga aaccugcaaa guacaaucca accgaguauu cugcgacacc augaacucca     1080

gaacccuccc cucagagguc aaccugugca acguagacau cuucaacccc aaauacgacu     1140

gcaaaauaau gaccucaaaa acagacgucu ccucuuccgu aaucaccagc cucggagcca     1200

ucgucagcug cuacggcaaa accaaaugca ccgccucaaa caaaugccgc ggcaucauca     1260

aaacauucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacaca guaagcguag     1320

gcaacacacu guacuacguc aacaaacaag agggaaaauc acucuacguc aaaggagaac     1380

ccauaaucaa cuucuacgac ccccucguuu uccccagcga cgaguucgac gccagcauau     1440

cccaagucaa cgagaaaauu aaccaauccc uagcauucau ccgaaaaucu gacgaacugc     1500

uccacaacgu caacgcggga aaaucaacaa ccaacauaau gauaaccaca aucauaauag     1560

ucaucaucgu aauccuccuc agccuaaucg cugucggccu ccuccucuac ugcaaagccc     1620

guuccacccc agucacacuu uccaaggacc aacuaagcgg aauaaacaac aucgcguucu     1680

caaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  5343
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5343
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5344
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5344
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5345
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5345
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5346
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5346
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggg     1680

auaaacaaua ucgcuuucuc aaacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5347
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5347
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5348
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5348
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucugga     1680

auuaacaaua ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5349
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5349
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuuaaagcc      120

aacgcaauaa caacaauucu cacugcuguc accuucugcu ucgccucagg ccaaaacaua      180

acggaagaau uuuaccaauc aacaugcucu gcaguaucca aaggcuaccu aucugcucua      240

agaacagguu gguauacauc aguaauaacc auagaacuau caaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguuaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguuaccg aacuacaacu acuuaugcaa uccacucccg ccacuggauc aggaucagca      420

auagcaucag gagucgcagu auguaaaguc uuacaccucg aaggcgaagu caauaaaauc      480

aaauccgcau uacuauccac aaacaaagca gucguauccc uaagcggaug cggaguauca      540

guacuaacau uuaaaguacu agaccuaaaa aauuacaucg auaaacaacu auuaccuaua      600

uuaaacaaac aauccugcuc cauuucaaau aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagau uacuagaaau aacaagagaa uuuuccguaa augcuggcgu aacaacacca      720

guauccacau acaugcucac aaacuccgaa cuacuaucac uaauaaauga caugcccaua      780

acaaacgauc aaaaaaaacu aaugucaaau aauguacaaa uaguaagaca acaaagcuac      840

uccaucaugu guauaauaaa agaagaagua cuagcauacg uaguucaacu accacuuuac      900

ggcguaaucg acaccccuug cuggaaacua cacaccuccc cucuaugcac cacaaacaca      960

aaagaagguu ccaacauaug ccuuaccaga acagacagag gcugguauug cgacaacgca     1020

ggaucaguuu cauuuuuucc acaagcugaa acaugcaaag uacaaucaaa cagagucuuc     1080

ugcgacacaa ugaacucaag aacucuaccc ucagaaguaa accuauguaa cguagacauu     1140

uucaacccca aauacgacug caaaauuaug acaucaaaaa cagacguuuc aucaucaguu     1200

aucaccucau uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucaaau     1260

aaaugcagag gaauaauaaa aacuuucucc aacggaugcg acuacguuuc aaacaaaggu     1320

guagacacug uaucaguagg aaacacacua uauuacguaa auaaacaaga aggaaaauca     1380

cuuuauguca aaggagaacc aauaaucaau uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug cuucaauauc acaaguaaac gaaaaaauaa aucaaucacu cgcauuuaua     1500

cgaaaaucag acgaacuacu acacaaugua aacgcaggca aaucaacaac aaacauaaug     1560

auaacaacaa uaaucauugu aauaauagua auacuucuau cucuaauagc aguaggauua     1620

cuccucuacu gcaaagcaag aucaaccccu guaacacuau caaaagacca acuuucaggu     1680

auaaauaaua uagcuuuuuc caauuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5350
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5350
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccuaau ccucaaagcc      120

aacgcgauca cuacaauccu cacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaggagu ucuaccaauc aaccugcucc gccguaucaa aaggauaccu aagcgcccua      240

cggaccggcu gguacacauc ugucaucacc aucgaacuau caaacaucaa agaaaacaaa      300

ugcaacggaa ccgacgcaaa agucaaacug auuaaacaag aacuagacaa auacaaaaac      360

gcagucaccg aacugcaauu acucaugcaa agcacaccgg ccaccggcuc aggcagcgcc      420

aucgccuccg gcgucgccgu cugcaaaguu cuccaccucg agggcgaagu caacaaaaua      480

aaaucugccc uccucuccac caacaaagcc gucgucuccc ucagcggcug cggagucucc      540

guccucaccu ucaaaguucu cgaucucaag aacuauauug acaaacaacu ucuacccaua      600

cucaacaaac aaagcugcag cauauccaac aucgaaaccg ucaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau aacccgcgag uucagcguua acgccggagu cacuaccccu      720

gucuccaccu acaugcucac caacuccgaa cuccuaucac uaaucaacga caugcccaua      780

accaacgacc agaagaaacu cauguccaac aacguccaaa uuguccgaca acaaagcuac      840

uccauaaugu gcauaauaaa agaggaaguc cucgccuacg ucguacaacu gccccuuuau      900

ggcguaaucg acacacccug cuggaaacuc cacacgucac cccucugcac caccaacaca      960

aaagaaggcu cgaacaucug ccuaacacgg acugaccgcg gcugguacug cgacaacgcc     1020

ggcuccguca gcuucuuccc acaagccgaa accugcaaag uacaauccaa ccgaguauuc     1080

ugcgacacca ugaacuccag aacccucccc ucagagguca accugugcaa cguagacauc     1140

uucaacccca aauacgacug caaaauaaug accucaaaaa cagacgucuc cucuuccgua     1200

aucaccagcc ucggagccau cgucagcugc uacggcaaaa ccaaaugcac cgccucaaac     1260

aaaugccgcg gcaucaucaa aacauucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag uaagcguagg caacacacug uacuacguca acaaacaaga gggaaaauca     1380

cucuacguca aaggagaacc cauaaucaac uucuacgacc cccucguuuu ccccagcgac     1440

gaguucgacg ccagcauauc ccaagucaac gagaaaauua accaaucccu agcauucauc     1500

cgaaaaucug acgaacugcu ccacaacguc aacgcgggaa aaucaacaac caacauaaug     1560

auaaccacaa ucauaauagu caucaucgua auccuccuca gccuaaucgc ugucggccuc     1620

cuccucuacu gcaaagcccg uuccacccca gucacacuuu ccaaggacca acuaagcgga     1680

auaaacaaca ucgcguucuc aaacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  5351
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5351
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5352
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5352
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5353
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5353
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5354
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5354
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1740

aaggaccagc ucuccgggau aaacaauauc gcuuucucaa acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5355
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5355
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5356
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5356
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1740

aaggaccagc ucucuggaau uaacaauauc gcguucucca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5357
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5357
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uuaaagccaa cgcaauaaca acaauucuca cugcugucac cuucugcuuc      240

gccucaggcc aaaacauaac ggaagaauuu uaccaaucaa caugcucugc aguauccaaa      300

ggcuaccuau cugcucuaag aacagguugg uauacaucag uaauaaccau agaacuauca      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uuaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguuaccgaa cuacaacuac uuaugcaauc cacucccgcc      480

acuggaucag gaucagcaau agcaucagga gucgcaguau guaaagucuu acaccucgaa      540

ggcgaaguca auaaaaucaa auccgcauua cuauccacaa acaaagcagu cguaucccua      600

agcggaugcg gaguaucagu acuaacauuu aaaguacuag accuaaaaaa uuacaucgau      660

aaacaacuau uaccuauauu aaacaaacaa uccugcucca uuucaaauau cgaaaccgua      720

auagaauuuc aacaaaaaaa caacagauua cuagaaauaa caagagaauu uuccguaaau      780

gcuggcguaa caacaccagu auccacauac augcucacaa acuccgaacu acuaucacua      840

auaaaugaca ugcccauaac aaacgaucaa aaaaaacuaa ugucaaauaa uguacaaaua      900

guaagacaac aaagcuacuc caucaugugu auaauaaaag aagaaguacu agcauacgua      960

guucaacuac cacuuuacgg cguaaucgac accccuugcu ggaaacuaca caccuccccu     1020

cuaugcacca caaacacaaa agaagguucc aacauaugcc uuaccagaac agacagaggc     1080

ugguauugcg acaacgcagg aucaguuuca uuuuuuccac aagcugaaac augcaaagua     1140

caaucaaaca gagucuucug cgacacaaug aacucaagaa cucuacccuc agaaguaaac     1200

cuauguaacg uagacauuuu caaccccaaa uacgacugca aaauuaugac aucaaaaaca     1260

gacguuucau caucaguuau caccucauua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucaaauaa augcagagga auaauaaaaa cuuucuccaa cggaugcgac     1380

uacguuucaa acaaaggugu agacacugua ucaguaggaa acacacuaua uuacguaaau     1440

aaacaagaag gaaaaucacu uuaugucaaa ggagaaccaa uaaucaauuu cuacgaccca     1500

uuaguauucc caucagacga auuugaugcu ucaauaucac aaguaaacga aaaaauaaau     1560

caaucacucg cauuuauacg aaaaucagac gaacuacuac acaauguaaa cgcaggcaaa     1620

ucaacaacaa acauaaugau aacaacaaua aucauuguaa uaauaguaau acuucuaucu     1680

cuaauagcag uaggauuacu ccucuacugc aaagcaagau caaccccugu aacacuauca     1740

aaagaccaac uuucagguau aaauaauaua gcuuuuucca auuaaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5358
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5358
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccuaaucc ucaaagccaa cgcgaucacu acaauccuca cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaggaguuc uaccaaucaa ccugcuccgc cguaucaaaa      300

ggauaccuaa gcgcccuacg gaccggcugg uacacaucug ucaucaccau cgaacuauca      360

aacaucaaag aaaacaaaug caacggaacc gacgcaaaag ucaaacugau uaaacaagaa      420

cuagacaaau acaaaaacgc agucaccgaa cugcaauuac ucaugcaaag cacaccggcc      480

accggcucag gcagcgccau cgccuccggc gucgccgucu gcaaaguucu ccaccucgag      540

ggcgaaguca acaaaauaaa aucugcccuc cucuccacca acaaagccgu cgucucccuc      600

agcggcugcg gagucuccgu ccucaccuuc aaaguucucg aucucaagaa cuauauugac      660

aaacaacuuc uacccauacu caacaaacaa agcugcagca uauccaacau cgaaaccguc      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauaa cccgcgaguu cagcguuaac      780

gccggaguca cuaccccugu cuccaccuac augcucacca acuccgaacu ccuaucacua      840

aucaacgaca ugcccauaac caacgaccag aagaaacuca uguccaacaa cguccaaauu      900

guccgacaac aaagcuacuc cauaaugugc auaauaaaag aggaaguccu cgccuacguc      960

guacaacugc cccuuuaugg cguaaucgac acacccugcu ggaaacucca cacgucaccc     1020

cucugcacca ccaacacaaa agaaggcucg aacaucugcc uaacacggac ugaccgcggc     1080

ugguacugcg acaacgccgg cuccgucagc uucuucccac aagccgaaac cugcaaagua     1140

caauccaacc gaguauucug cgacaccaug aacuccagaa cccuccccuc agaggucaac     1200

cugugcaacg uagacaucuu caaccccaaa uacgacugca aaauaaugac cucaaaaaca     1260

gacgucuccu cuuccguaau caccagccuc ggagccaucg ucagcugcua cggcaaaacc     1320

aaaugcaccg ccucaaacaa augccgcggc aucaucaaaa cauucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacacagua agcguaggca acacacugua cuacgucaac     1440

aaacaagagg gaaaaucacu cuacgucaaa ggagaaccca uaaucaacuu cuacgacccc     1500

cucguuuucc ccagcgacga guucgacgcc agcauauccc aagucaacga gaaaauuaac     1560

caaucccuag cauucauccg aaaaucugac gaacugcucc acaacgucaa cgcgggaaaa     1620

ucaacaacca acauaaugau aaccacaauc auaauaguca ucaucguaau ccuccucagc     1680

cuaaucgcug ucggccuccu ccucuacugc aaagcccguu ccaccccagu cacacuuucc     1740

aaggaccaac uaagcggaau aaacaacauc gcguucucaa acuaaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  5359
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5359
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5360
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5360
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccgguc caccccggug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5361
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5361
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5362
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5362
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcuc uacaccggug     1680

acccugagca aggaccagcu cuccgggaua aacaauaucg cuuucucaaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5363
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5363
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5364
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5364
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagauc cacaccugug     1680

acccuuagca aggaccagcu cucuggaauu aacaauaucg cguucuccaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5365
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5365
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu uaaagccaac gcaauaacaa caauucucac ugcugucacc      180

uucugcuucg ccucaggcca aaacauaacg gaagaauuuu accaaucaac augcucugca      240

guauccaaag gcuaccuauc ugcucuaaga acagguuggu auacaucagu aauaaccaua      300

gaacuaucaa acauaaaaga aaauaaaugc aacggaacag acgcaaaagu uaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guuaccgaac uacaacuacu uaugcaaucc      420

acucccgcca cuggaucagg aucagcaaua gcaucaggag ucgcaguaug uaaagucuua      480

caccucgaag gcgaagucaa uaaaaucaaa uccgcauuac uauccacaaa caaagcaguc      540

guaucccuaa gcggaugcgg aguaucagua cuaacauuua aaguacuaga ccuaaaaaau      600

uacaucgaua aacaacuauu accuauauua aacaaacaau ccugcuccau uucaaauauc      660

gaaaccguaa uagaauuuca acaaaaaaac aacagauuac uagaaauaac aagagaauuu      720

uccguaaaug cuggcguaac aacaccagua uccacauaca ugcucacaaa cuccgaacua      780

cuaucacuaa uaaaugacau gcccauaaca aacgaucaaa aaaaacuaau gucaaauaau      840

guacaaauag uaagacaaca aagcuacucc aucaugugua uaauaaaaga agaaguacua      900

gcauacguag uucaacuacc acuuuacggc guaaucgaca ccccuugcug gaaacuacac      960

accuccccuc uaugcaccac aaacacaaaa gaagguucca acauaugccu uaccagaaca     1020

gacagaggcu gguauugcga caacgcagga ucaguuucau uuuuuccaca agcugaaaca     1080

ugcaaaguac aaucaaacag agucuucugc gacacaauga acucaagaac ucuacccuca     1140

gaaguaaacc uauguaacgu agacauuuuc aaccccaaau acgacugcaa aauuaugaca     1200

ucaaaaacag acguuucauc aucaguuauc accucauuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucaaauaaa ugcagaggaa uaauaaaaac uuucuccaac     1320

ggaugcgacu acguuucaaa caaaggugua gacacuguau caguaggaaa cacacuauau     1380

uacguaaaua aacaagaagg aaaaucacuu uaugucaaag gagaaccaau aaucaauuuc     1440

uacgacccau uaguauuccc aucagacgaa uuugaugcuu caauaucaca aguaaacgaa     1500

aaaauaaauc aaucacucgc auuuauacga aaaucagacg aacuacuaca caauguaaac     1560

gcaggcaaau caacaacaaa cauaaugaua acaacaauaa ucauuguaau aauaguaaua     1620

cuucuaucuc uaauagcagu aggauuacuc cucuacugca aagcaagauc aaccccugua     1680

acacuaucaa aagaccaacu uucagguaua aauaauauag cuuuuuccaa uuaaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5366
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5366
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccuaauccu caaagccaac gcgaucacua caauccucac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaggaguucu accaaucaac cugcuccgcc      240

guaucaaaag gauaccuaag cgcccuacgg accggcuggu acacaucugu caucaccauc      300

gaacuaucaa acaucaaaga aaacaaaugc aacggaaccg acgcaaaagu caaacugauu      360

aaacaagaac uagacaaaua caaaaacgca gucaccgaac ugcaauuacu caugcaaagc      420

acaccggcca ccggcucagg cagcgccauc gccuccggcg ucgccgucug caaaguucuc      480

caccucgagg gcgaagucaa caaaauaaaa ucugcccucc ucuccaccaa caaagccguc      540

gucucccuca gcggcugcgg agucuccguc cucaccuuca aaguucucga ucucaagaac      600

uauauugaca aacaacuucu acccauacuc aacaaacaaa gcugcagcau auccaacauc      660

gaaaccguca ucgaguucca acaaaagaac aaccgccucc ucgaaauaac ccgcgaguuc      720

agcguuaacg ccggagucac uaccccuguc uccaccuaca ugcucaccaa cuccgaacuc      780

cuaucacuaa ucaacgacau gcccauaacc aacgaccaga agaaacucau guccaacaac      840

guccaaauug uccgacaaca aagcuacucc auaaugugca uaauaaaaga ggaaguccuc      900

gccuacgucg uacaacugcc ccuuuauggc guaaucgaca cacccugcug gaaacuccac      960

acgucacccc ucugcaccac caacacaaaa gaaggcucga acaucugccu aacacggacu     1020

gaccgcggcu gguacugcga caacgccggc uccgucagcu ucuucccaca agccgaaacc     1080

ugcaaaguac aauccaaccg aguauucugc gacaccauga acuccagaac ccuccccuca     1140

gaggucaacc ugugcaacgu agacaucuuc aaccccaaau acgacugcaa aauaaugacc     1200

ucaaaaacag acgucuccuc uuccguaauc accagccucg gagccaucgu cagcugcuac     1260

ggcaaaacca aaugcaccgc cucaaacaaa ugccgcggca ucaucaaaac auucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacacaguaa gcguaggcaa cacacuguac     1380

uacgucaaca aacaagaggg aaaaucacuc uacgucaaag gagaacccau aaucaacuuc     1440

uacgaccccc ucguuuuccc cagcgacgag uucgacgcca gcauauccca agucaacgag     1500

aaaauuaacc aaucccuagc auucauccga aaaucugacg aacugcucca caacgucaac     1560

gcgggaaaau caacaaccaa cauaaugaua accacaauca uaauagucau caucguaauc     1620

cuccucagcc uaaucgcugu cggccuccuc cucuacugca aagcccguuc caccccaguc     1680

acacuuucca aggaccaacu aagcggaaua aacaacaucg cguucucaaa cuaaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  5367
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5367
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5368
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5368
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccgguccacc     1620

ccggugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5369
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5369
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5370
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5370
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcucuaca     1620

ccggugaccc ugagcaagga ccagcucucc gggauaaaca auaucgcuuu cucaaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5371
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5371
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5372
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5372
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagauccaca     1620

ccugugaccc uuagcaagga ccagcucucu ggaauuaaca auaucgcguu cuccaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5373
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5373
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuuaaa gccaacgcaa uaacaacaau ucucacugcu      120

gucaccuucu gcuucgccuc aggccaaaac auaacggaag aauuuuacca aucaacaugc      180

ucugcaguau ccaaaggcua ccuaucugcu cuaagaacag guugguauac aucaguaaua      240

accauagaac uaucaaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguuaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguua ccgaacuaca acuacuuaug      360

caauccacuc ccgccacugg aucaggauca gcaauagcau caggagucgc aguauguaaa      420

gucuuacacc ucgaaggcga agucaauaaa aucaaauccg cauuacuauc cacaaacaaa      480

gcagucguau cccuaagcgg augcggagua ucaguacuaa cauuuaaagu acuagaccua      540

aaaaauuaca ucgauaaaca acuauuaccu auauuaaaca aacaauccug cuccauuuca      600

aauaucgaaa ccguaauaga auuucaacaa aaaaacaaca gauuacuaga aauaacaaga      660

gaauuuuccg uaaaugcugg cguaacaaca ccaguaucca cauacaugcu cacaaacucc      720

gaacuacuau cacuaauaaa ugacaugccc auaacaaacg aucaaaaaaa acuaauguca      780

aauaauguac aaauaguaag acaacaaagc uacuccauca uguguauaau aaaagaagaa      840

guacuagcau acguaguuca acuaccacuu uacggcguaa ucgacacccc uugcuggaaa      900

cuacacaccu ccccucuaug caccacaaac acaaaagaag guuccaacau augccuuacc      960

agaacagaca gaggcuggua uugcgacaac gcaggaucag uuucauuuuu uccacaagcu     1020

gaaacaugca aaguacaauc aaacagaguc uucugcgaca caaugaacuc aagaacucua     1080

cccucagaag uaaaccuaug uaacguagac auuuucaacc ccaaauacga cugcaaaauu     1140

augacaucaa aaacagacgu uucaucauca guuaucaccu cauuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccuca aauaaaugca gaggaauaau aaaaacuuuc     1260

uccaacggau gcgacuacgu uucaaacaaa gguguagaca cuguaucagu aggaaacaca     1320

cuauauuacg uaaauaaaca agaaggaaaa ucacuuuaug ucaaaggaga accaauaauc     1380

aauuucuacg acccauuagu auucccauca gacgaauuug augcuucaau aucacaagua     1440

aacgaaaaaa uaaaucaauc acucgcauuu auacgaaaau cagacgaacu acuacacaau     1500

guaaacgcag gcaaaucaac aacaaacaua augauaacaa caauaaucau uguaauaaua     1560

guaauacuuc uaucucuaau agcaguagga uuacuccucu acugcaaagc aagaucaacc     1620

ccuguaacac uaucaaaaga ccaacuuuca gguauaaaua auauagcuuu uuccaauuaa     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5374
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5374
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu aauccucaaa gccaacgcga ucacuacaau ccucacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgagg aguucuacca aucaaccugc      180

uccgccguau caaaaggaua ccuaagcgcc cuacggaccg gcugguacac aucugucauc      240

accaucgaac uaucaaacau caaagaaaac aaaugcaacg gaaccgacgc aaaagucaaa      300

cugauuaaac aagaacuaga caaauacaaa aacgcaguca ccgaacugca auuacucaug      360

caaagcacac cggccaccgg cucaggcagc gccaucgccu ccggcgucgc cgucugcaaa      420

guucuccacc ucgagggcga agucaacaaa auaaaaucug cccuccucuc caccaacaaa      480

gccgucgucu cccucagcgg cugcggaguc uccguccuca ccuucaaagu ucucgaucuc      540

aagaacuaua uugacaaaca acuucuaccc auacucaaca aacaaagcug cagcauaucc      600

aacaucgaaa ccgucaucga guuccaacaa aagaacaacc gccuccucga aauaacccgc      660

gaguucagcg uuaacgccgg agucacuacc ccugucucca ccuacaugcu caccaacucc      720

gaacuccuau cacuaaucaa cgacaugccc auaaccaacg accagaagaa acucaugucc      780

aacaacgucc aaauuguccg acaacaaagc uacuccauaa ugugcauaau aaaagaggaa      840

guccucgccu acgucguaca acugccccuu uauggcguaa ucgacacacc cugcuggaaa      900

cuccacacgu caccccucug caccaccaac acaaaagaag gcucgaacau cugccuaaca      960

cggacugacc gcggcuggua cugcgacaac gccggcuccg ucagcuucuu cccacaagcc     1020

gaaaccugca aaguacaauc caaccgagua uucugcgaca ccaugaacuc cagaacccuc     1080

cccucagagg ucaaccugug caacguagac aucuucaacc ccaaauacga cugcaaaaua     1140

augaccucaa aaacagacgu cuccucuucc guaaucacca gccucggagc caucgucagc     1200

ugcuacggca aaaccaaaug caccgccuca aacaaaugcc gcggcaucau caaaacauuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca caguaagcgu aggcaacaca     1320

cuguacuacg ucaacaaaca agagggaaaa ucacucuacg ucaaaggaga acccauaauc     1380

aacuucuacg acccccucgu uuuccccagc gacgaguucg acgccagcau aucccaaguc     1440

aacgagaaaa uuaaccaauc ccuagcauuc auccgaaaau cugacgaacu gcuccacaac     1500

gucaacgcgg gaaaaucaac aaccaacaua augauaacca caaucauaau agucaucauc     1560

guaauccucc ucagccuaau cgcugucggc cuccuccucu acugcaaagc ccguuccacc     1620

ccagucacac uuuccaagga ccaacuaagc ggaauaaaca acaucgcguu cucaaacuaa     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  5375
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5375
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5376
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5376
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      600

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      660

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      720

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      840

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc     1080

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg     1140

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1260

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1380

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1620

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1740

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguccacccc ggugacccug     1800

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5377
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5377
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5378
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5378
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      600

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      660

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      720

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      780

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      840

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      900

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      960

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau     1020

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc     1080

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu     1140

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1200

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1260

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1320

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1380

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1440

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1500

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1560

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1620

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1680

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1740

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcucuacacc ggugacccug     1800

agcaaggacc agcucuccgg gauaaacaau aucgcuuucu caaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5379
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5379
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5380
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5380
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      600

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      660

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      720

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      780

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      840

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      900

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      960

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau     1020

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu     1080

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc     1140

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1200

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1260

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1320

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1380

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1440

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1500

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1560

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1620

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1680

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1740

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gauccacacc ugugacccuu     1800

agcaaggacc agcucucugg aauuaacaau aucgcguucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5381
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5381
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc ucacugcugu caccuucugc      300

uucgccucag gccaaaacau aacggaagaa uuuuaccaau caacaugcuc ugcaguaucc      360

aaaggcuacc uaucugcucu aagaacaggu ugguauacau caguaauaac cauagaacua      420

ucaaacauaa aagaaaauaa augcaacgga acagacgcaa aaguuaaacu cauaaaacaa      480

gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac uacuuaugca auccacuccc      540

gccacuggau caggaucagc aauagcauca ggagucgcag uauguaaagu cuuacaccuc      600

gaaggcgaag ucaauaaaau caaauccgca uuacuaucca caaacaaagc agucguaucc      660

cuaagcggau gcggaguauc aguacuaaca uuuaaaguac uagaccuaaa aaauuacauc      720

gauaaacaac uauuaccuau auuaaacaaa caauccugcu ccauuucaaa uaucgaaacc      780

guaauagaau uucaacaaaa aaacaacaga uuacuagaaa uaacaagaga auuuuccgua      840

aaugcuggcg uaacaacacc aguauccaca uacaugcuca caaacuccga acuacuauca      900

cuaauaaaug acaugcccau aacaaacgau caaaaaaaac uaaugucaaa uaauguacaa      960

auaguaagac aacaaagcua cuccaucaug uguauaauaa aagaagaagu acuagcauac     1020

guaguucaac uaccacuuua cggcguaauc gacaccccuu gcuggaaacu acacaccucc     1080

ccucuaugca ccacaaacac aaaagaaggu uccaacauau gccuuaccag aacagacaga     1140

ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc cacaagcuga aacaugcaaa     1200

guacaaucaa acagagucuu cugcgacaca augaacucaa gaacucuacc cucagaagua     1260

aaccuaugua acguagacau uuucaacccc aaauacgacu gcaaaauuau gacaucaaaa     1320

acagacguuu caucaucagu uaucaccuca uuaggagcaa uaguaagcug cuacggaaaa     1380

acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa aaacuuucuc caacggaugc     1440

gacuacguuu caaacaaagg uguagacacu guaucaguag gaaacacacu auauuacgua     1500

aauaaacaag aaggaaaauc acuuuauguc aaaggagaac caauaaucaa uuucuacgac     1560

ccauuaguau ucccaucaga cgaauuugau gcuucaauau cacaaguaaa cgaaaaaaua     1620

aaucaaucac ucgcauuuau acgaaaauca gacgaacuac uacacaaugu aaacgcaggc     1680

aaaucaacaa caaacauaau gauaacaaca auaaucauug uaauaauagu aauacuucua     1740

ucucuaauag caguaggauu acuccucuac ugcaaagcaa gaucaacccc uguaacacua     1800

ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu ccaauuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5382
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5382
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuaa uccucaaagc caacgcgauc acuacaaucc ucacagccgu caccuucugc      300

uucgccuccg gccaaaacau caccgaggag uucuaccaau caaccugcuc cgccguauca      360

aaaggauacc uaagcgcccu acggaccggc ugguacacau cugucaucac caucgaacua      420

ucaaacauca aagaaaacaa augcaacgga accgacgcaa aagucaaacu gauuaaacaa      480

gaacuagaca aauacaaaaa cgcagucacc gaacugcaau uacucaugca aagcacaccg      540

gccaccggcu caggcagcgc caucgccucc ggcgucgccg ucugcaaagu ucuccaccuc      600

gagggcgaag ucaacaaaau aaaaucugcc cuccucucca ccaacaaagc cgucgucucc      660

cucagcggcu gcggagucuc cguccucacc uucaaaguuc ucgaucucaa gaacuauauu      720

gacaaacaac uucuacccau acucaacaaa caaagcugca gcauauccaa caucgaaacc      780

gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa uaacccgcga guucagcguu      840

aacgccggag ucacuacccc ugucuccacc uacaugcuca ccaacuccga acuccuauca      900

cuaaucaacg acaugcccau aaccaacgac cagaagaaac ucauguccaa caacguccaa      960

auuguccgac aacaaagcua cuccauaaug ugcauaauaa aagaggaagu ccucgccuac     1020

gucguacaac ugccccuuua uggcguaauc gacacacccu gcuggaaacu ccacacguca     1080

ccccucugca ccaccaacac aaaagaaggc ucgaacaucu gccuaacacg gacugaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc agcuucuucc cacaagccga aaccugcaaa     1200

guacaaucca accgaguauu cugcgacacc augaacucca gaacccuccc cucagagguc     1260

aaccugugca acguagacau cuucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1320

acagacgucu ccucuuccgu aaucaccagc cucggagcca ucgucagcug cuacggcaaa     1380

accaaaugca ccgccucaaa caaaugccgc ggcaucauca aaacauucuc aaacggcugc     1440

gacuacgucu ccaacaaagg cgucgacaca guaagcguag gcaacacacu guacuacguc     1500

aacaaacaag agggaaaauc acucuacguc aaaggagaac ccauaaucaa cuucuacgac     1560

ccccucguuu uccccagcga cgaguucgac gccagcauau cccaagucaa cgagaaaauu     1620

aaccaauccc uagcauucau ccgaaaaucu gacgaacugc uccacaacgu caacgcggga     1680

aaaucaacaa ccaacauaau gauaaccaca aucauaauag ucaucaucgu aauccuccuc     1740

agccuaaucg cugucggccu ccuccucuac ugcaaagccc guuccacccc agucacacuu     1800

uccaaggacc aacuaagcgg aauaaacaac aucgcguucu caaacuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5383
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5383
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1620

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5384
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5384
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1080

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1200

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguccacccc ggugacccug     1620

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5385
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5385
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1620

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5386
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5386
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      540

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      600

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      660

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      720

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      780

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau      840

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc      900

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu      960

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1020

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1080

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1140

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1200

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1260

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1320

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1440

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1500

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1560

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcucuacacc ggugacccug     1620

agcaaggacc agcucuccgg gauaaacaau aucgcuuucu caaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5387
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5387
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1620

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5388
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5388
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      540

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      600

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      660

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      720

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      780

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau      840

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu      900

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc      960

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1020

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1080

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1140

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1200

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1260

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1320

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1440

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1500

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1560

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gauccacacc ugugacccuu     1620

agcaaggacc agcucucugg aauuaacaau aucgcguucu ccaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5389
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5389
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc ucacugcugu caccuucugc      120

uucgccucag gccaaaacau aacggaagaa uuuuaccaau caacaugcuc ugcaguaucc      180

aaaggcuacc uaucugcucu aagaacaggu ugguauacau caguaauaac cauagaacua      240

ucaaacauaa aagaaaauaa augcaacgga acagacgcaa aaguuaaacu cauaaaacaa      300

gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac uacuuaugca auccacuccc      360

gccacuggau caggaucagc aauagcauca ggagucgcag uauguaaagu cuuacaccuc      420

gaaggcgaag ucaauaaaau caaauccgca uuacuaucca caaacaaagc agucguaucc      480

cuaagcggau gcggaguauc aguacuaaca uuuaaaguac uagaccuaaa aaauuacauc      540

gauaaacaac uauuaccuau auuaaacaaa caauccugcu ccauuucaaa uaucgaaacc      600

guaauagaau uucaacaaaa aaacaacaga uuacuagaaa uaacaagaga auuuuccgua      660

aaugcuggcg uaacaacacc aguauccaca uacaugcuca caaacuccga acuacuauca      720

cuaauaaaug acaugcccau aacaaacgau caaaaaaaac uaaugucaaa uaauguacaa      780

auaguaagac aacaaagcua cuccaucaug uguauaauaa aagaagaagu acuagcauac      840

guaguucaac uaccacuuua cggcguaauc gacaccccuu gcuggaaacu acacaccucc      900

ccucuaugca ccacaaacac aaaagaaggu uccaacauau gccuuaccag aacagacaga      960

ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc cacaagcuga aacaugcaaa     1020

guacaaucaa acagagucuu cugcgacaca augaacucaa gaacucuacc cucagaagua     1080

aaccuaugua acguagacau uuucaacccc aaauacgacu gcaaaauuau gacaucaaaa     1140

acagacguuu caucaucagu uaucaccuca uuaggagcaa uaguaagcug cuacggaaaa     1200

acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa aaacuuucuc caacggaugc     1260

gacuacguuu caaacaaagg uguagacacu guaucaguag gaaacacacu auauuacgua     1320

aauaaacaag aaggaaaauc acuuuauguc aaaggagaac caauaaucaa uuucuacgac     1380

ccauuaguau ucccaucaga cgaauuugau gcuucaauau cacaaguaaa cgaaaaaaua     1440

aaucaaucac ucgcauuuau acgaaaauca gacgaacuac uacacaaugu aaacgcaggc     1500

aaaucaacaa caaacauaau gauaacaaca auaaucauug uaauaauagu aauacuucua     1560

ucucuaauag caguaggauu acuccucuac ugcaaagcaa gaucaacccc uguaacacua     1620

ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu ccaauuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5390
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5390
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuaa uccucaaagc caacgcgauc acuacaaucc ucacagccgu caccuucugc      120

uucgccuccg gccaaaacau caccgaggag uucuaccaau caaccugcuc cgccguauca      180

aaaggauacc uaagcgcccu acggaccggc ugguacacau cugucaucac caucgaacua      240

ucaaacauca aagaaaacaa augcaacgga accgacgcaa aagucaaacu gauuaaacaa      300

gaacuagaca aauacaaaaa cgcagucacc gaacugcaau uacucaugca aagcacaccg      360

gccaccggcu caggcagcgc caucgccucc ggcgucgccg ucugcaaagu ucuccaccuc      420

gagggcgaag ucaacaaaau aaaaucugcc cuccucucca ccaacaaagc cgucgucucc      480

cucagcggcu gcggagucuc cguccucacc uucaaaguuc ucgaucucaa gaacuauauu      540

gacaaacaac uucuacccau acucaacaaa caaagcugca gcauauccaa caucgaaacc      600

gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa uaacccgcga guucagcguu      660

aacgccggag ucacuacccc ugucuccacc uacaugcuca ccaacuccga acuccuauca      720

cuaaucaacg acaugcccau aaccaacgac cagaagaaac ucauguccaa caacguccaa      780

auuguccgac aacaaagcua cuccauaaug ugcauaauaa aagaggaagu ccucgccuac      840

gucguacaac ugccccuuua uggcguaauc gacacacccu gcuggaaacu ccacacguca      900

ccccucugca ccaccaacac aaaagaaggc ucgaacaucu gccuaacacg gacugaccgc      960

ggcugguacu gcgacaacgc cggcuccguc agcuucuucc cacaagccga aaccugcaaa     1020

guacaaucca accgaguauu cugcgacacc augaacucca gaacccuccc cucagagguc     1080

aaccugugca acguagacau cuucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1140

acagacgucu ccucuuccgu aaucaccagc cucggagcca ucgucagcug cuacggcaaa     1200

accaaaugca ccgccucaaa caaaugccgc ggcaucauca aaacauucuc aaacggcugc     1260

gacuacgucu ccaacaaagg cgucgacaca guaagcguag gcaacacacu guacuacguc     1320

aacaaacaag agggaaaauc acucuacguc aaaggagaac ccauaaucaa cuucuacgac     1380

ccccucguuu uccccagcga cgaguucgac gccagcauau cccaagucaa cgagaaaauu     1440

aaccaauccc uagcauucau ccgaaaaucu gacgaacugc uccacaacgu caacgcggga     1500

aaaucaacaa ccaacauaau gauaaccaca aucauaauag ucaucaucgu aauccuccuc     1560

agccuaaucg cugucggccu ccuccucuac ugcaaagccc guuccacccc agucacacuu     1620

uccaaggacc aacuaagcgg aauaaacaac aucgcguucu caaacuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  5391
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5391
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5392
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5392
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

gguccacccc ggugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5393
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5393
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5394
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5394
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcucuacacc ggugacccug agcaaggacc agcucuccgg gauaaacaau aucgcuuucu     1680

caaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5395
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5395
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5396
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5396
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gauccacacc ugugacccuu agcaaggacc agcucucugg aauuaacaau aucgcguucu     1680

ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5397
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5397
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc      120

ucacugcugu caccuucugc uucgccucag gccaaaacau aacggaagaa uuuuaccaau      180

caacaugcuc ugcaguaucc aaaggcuacc uaucugcucu aagaacaggu ugguauacau      240

caguaauaac cauagaacua ucaaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguuaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac      360

uacuuaugca auccacuccc gccacuggau caggaucagc aauagcauca ggagucgcag      420

uauguaaagu cuuacaccuc gaaggcgaag ucaauaaaau caaauccgca uuacuaucca      480

caaacaaagc agucguaucc cuaagcggau gcggaguauc aguacuaaca uuuaaaguac      540

uagaccuaaa aaauuacauc gauaaacaac uauuaccuau auuaaacaaa caauccugcu      600

ccauuucaaa uaucgaaacc guaauagaau uucaacaaaa aaacaacaga uuacuagaaa      660

uaacaagaga auuuuccgua aaugcuggcg uaacaacacc aguauccaca uacaugcuca      720

caaacuccga acuacuauca cuaauaaaug acaugcccau aacaaacgau caaaaaaaac      780

uaaugucaaa uaauguacaa auaguaagac aacaaagcua cuccaucaug uguauaauaa      840

aagaagaagu acuagcauac guaguucaac uaccacuuua cggcguaauc gacaccccuu      900

gcuggaaacu acacaccucc ccucuaugca ccacaaacac aaaagaaggu uccaacauau      960

gccuuaccag aacagacaga ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc     1020

cacaagcuga aacaugcaaa guacaaucaa acagagucuu cugcgacaca augaacucaa     1080

gaacucuacc cucagaagua aaccuaugua acguagacau uuucaacccc aaauacgacu     1140

gcaaaauuau gacaucaaaa acagacguuu caucaucagu uaucaccuca uuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa     1260

aaacuuucuc caacggaugc gacuacguuu caaacaaagg uguagacacu guaucaguag     1320

gaaacacacu auauuacgua aauaaacaag aaggaaaauc acuuuauguc aaaggagaac     1380

caauaaucaa uuucuacgac ccauuaguau ucccaucaga cgaauuugau gcuucaauau     1440

cacaaguaaa cgaaaaaaua aaucaaucac ucgcauuuau acgaaaauca gacgaacuac     1500

uacacaaugu aaacgcaggc aaaucaacaa caaacauaau gauaacaaca auaaucauug     1560

uaauaauagu aauacuucua ucucuaauag caguaggauu acuccucuac ugcaaagcaa     1620

gaucaacccc uguaacacua ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu     1680

ccaauuaagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5398
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5398
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuaa uccucaaagc caacgcgauc acuacaaucc      120

ucacagccgu caccuucugc uucgccuccg gccaaaacau caccgaggag uucuaccaau      180

caaccugcuc cgccguauca aaaggauacc uaagcgcccu acggaccggc ugguacacau      240

cugucaucac caucgaacua ucaaacauca aagaaaacaa augcaacgga accgacgcaa      300

aagucaaacu gauuaaacaa gaacuagaca aauacaaaaa cgcagucacc gaacugcaau      360

uacucaugca aagcacaccg gccaccggcu caggcagcgc caucgccucc ggcgucgccg      420

ucugcaaagu ucuccaccuc gagggcgaag ucaacaaaau aaaaucugcc cuccucucca      480

ccaacaaagc cgucgucucc cucagcggcu gcggagucuc cguccucacc uucaaaguuc      540

ucgaucucaa gaacuauauu gacaaacaac uucuacccau acucaacaaa caaagcugca      600

gcauauccaa caucgaaacc gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

uaacccgcga guucagcguu aacgccggag ucacuacccc ugucuccacc uacaugcuca      720

ccaacuccga acuccuauca cuaaucaacg acaugcccau aaccaacgac cagaagaaac      780

ucauguccaa caacguccaa auuguccgac aacaaagcua cuccauaaug ugcauaauaa      840

aagaggaagu ccucgccuac gucguacaac ugccccuuua uggcguaauc gacacacccu      900

gcuggaaacu ccacacguca ccccucugca ccaccaacac aaaagaaggc ucgaacaucu      960

gccuaacacg gacugaccgc ggcugguacu gcgacaacgc cggcuccguc agcuucuucc     1020

cacaagccga aaccugcaaa guacaaucca accgaguauu cugcgacacc augaacucca     1080

gaacccuccc cucagagguc aaccugugca acguagacau cuucaacccc aaauacgacu     1140

gcaaaauaau gaccucaaaa acagacgucu ccucuuccgu aaucaccagc cucggagcca     1200

ucgucagcug cuacggcaaa accaaaugca ccgccucaaa caaaugccgc ggcaucauca     1260

aaacauucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacaca guaagcguag     1320

gcaacacacu guacuacguc aacaaacaag agggaaaauc acucuacguc aaaggagaac     1380

ccauaaucaa cuucuacgac ccccucguuu uccccagcga cgaguucgac gccagcauau     1440

cccaagucaa cgagaaaauu aaccaauccc uagcauucau ccgaaaaucu gacgaacugc     1500

uccacaacgu caacgcggga aaaucaacaa ccaacauaau gauaaccaca aucauaauag     1560

ucaucaucgu aauccuccuc agccuaaucg cugucggccu ccuccucuac ugcaaagccc     1620

guuccacccc agucacacuu uccaaggacc aacuaagcgg aauaaacaac aucgcguucu     1680

caaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5399
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5399
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5400
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5400
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

gguccacccc ggugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5401
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5401
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5402
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5402
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcucuacacc ggugacccug agcaaggacc agcucuccgg gauaaacaau aucgcuuucu     1680

caaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5403
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5403
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5404
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5404
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gauccacacc ugugacccuu agcaaggacc agcucucugg aauuaacaau aucgcguucu     1680

ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5405
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5405
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc      120

ucacugcugu caccuucugc uucgccucag gccaaaacau aacggaagaa uuuuaccaau      180

caacaugcuc ugcaguaucc aaaggcuacc uaucugcucu aagaacaggu ugguauacau      240

caguaauaac cauagaacua ucaaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguuaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac      360

uacuuaugca auccacuccc gccacuggau caggaucagc aauagcauca ggagucgcag      420

uauguaaagu cuuacaccuc gaaggcgaag ucaauaaaau caaauccgca uuacuaucca      480

caaacaaagc agucguaucc cuaagcggau gcggaguauc aguacuaaca uuuaaaguac      540

uagaccuaaa aaauuacauc gauaaacaac uauuaccuau auuaaacaaa caauccugcu      600

ccauuucaaa uaucgaaacc guaauagaau uucaacaaaa aaacaacaga uuacuagaaa      660

uaacaagaga auuuuccgua aaugcuggcg uaacaacacc aguauccaca uacaugcuca      720

caaacuccga acuacuauca cuaauaaaug acaugcccau aacaaacgau caaaaaaaac      780

uaaugucaaa uaauguacaa auaguaagac aacaaagcua cuccaucaug uguauaauaa      840

aagaagaagu acuagcauac guaguucaac uaccacuuua cggcguaauc gacaccccuu      900

gcuggaaacu acacaccucc ccucuaugca ccacaaacac aaaagaaggu uccaacauau      960

gccuuaccag aacagacaga ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc     1020

cacaagcuga aacaugcaaa guacaaucaa acagagucuu cugcgacaca augaacucaa     1080

gaacucuacc cucagaagua aaccuaugua acguagacau uuucaacccc aaauacgacu     1140

gcaaaauuau gacaucaaaa acagacguuu caucaucagu uaucaccuca uuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa     1260

aaacuuucuc caacggaugc gacuacguuu caaacaaagg uguagacacu guaucaguag     1320

gaaacacacu auauuacgua aauaaacaag aaggaaaauc acuuuauguc aaaggagaac     1380

caauaaucaa uuucuacgac ccauuaguau ucccaucaga cgaauuugau gcuucaauau     1440

cacaaguaaa cgaaaaaaua aaucaaucac ucgcauuuau acgaaaauca gacgaacuac     1500

uacacaaugu aaacgcaggc aaaucaacaa caaacauaau gauaacaaca auaaucauug     1560

uaauaauagu aauacuucua ucucuaauag caguaggauu acuccucuac ugcaaagcaa     1620

gaucaacccc uguaacacua ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu     1680

ccaauuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5406
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5406
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuaa uccucaaagc caacgcgauc acuacaaucc      120

ucacagccgu caccuucugc uucgccuccg gccaaaacau caccgaggag uucuaccaau      180

caaccugcuc cgccguauca aaaggauacc uaagcgcccu acggaccggc ugguacacau      240

cugucaucac caucgaacua ucaaacauca aagaaaacaa augcaacgga accgacgcaa      300

aagucaaacu gauuaaacaa gaacuagaca aauacaaaaa cgcagucacc gaacugcaau      360

uacucaugca aagcacaccg gccaccggcu caggcagcgc caucgccucc ggcgucgccg      420

ucugcaaagu ucuccaccuc gagggcgaag ucaacaaaau aaaaucugcc cuccucucca      480

ccaacaaagc cgucgucucc cucagcggcu gcggagucuc cguccucacc uucaaaguuc      540

ucgaucucaa gaacuauauu gacaaacaac uucuacccau acucaacaaa caaagcugca      600

gcauauccaa caucgaaacc gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

uaacccgcga guucagcguu aacgccggag ucacuacccc ugucuccacc uacaugcuca      720

ccaacuccga acuccuauca cuaaucaacg acaugcccau aaccaacgac cagaagaaac      780

ucauguccaa caacguccaa auuguccgac aacaaagcua cuccauaaug ugcauaauaa      840

aagaggaagu ccucgccuac gucguacaac ugccccuuua uggcguaauc gacacacccu      900

gcuggaaacu ccacacguca ccccucugca ccaccaacac aaaagaaggc ucgaacaucu      960

gccuaacacg gacugaccgc ggcugguacu gcgacaacgc cggcuccguc agcuucuucc     1020

cacaagccga aaccugcaaa guacaaucca accgaguauu cugcgacacc augaacucca     1080

gaacccuccc cucagagguc aaccugugca acguagacau cuucaacccc aaauacgacu     1140

gcaaaauaau gaccucaaaa acagacgucu ccucuuccgu aaucaccagc cucggagcca     1200

ucgucagcug cuacggcaaa accaaaugca ccgccucaaa caaaugccgc ggcaucauca     1260

aaacauucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacaca guaagcguag     1320

gcaacacacu guacuacguc aacaaacaag agggaaaauc acucuacguc aaaggagaac     1380

ccauaaucaa cuucuacgac ccccucguuu uccccagcga cgaguucgac gccagcauau     1440

cccaagucaa cgagaaaauu aaccaauccc uagcauucau ccgaaaaucu gacgaacugc     1500

uccacaacgu caacgcggga aaaucaacaa ccaacauaau gauaaccaca aucauaauag     1560

ucaucaucgu aauccuccuc agccuaaucg cugucggccu ccuccucuac ugcaaagccc     1620

guuccacccc agucacacuu uccaaggacc aacuaagcgg aauaaacaac aucgcguucu     1680

caaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  5407
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5407
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5408
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5408
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccgguc caccccggug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5409
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5409
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5410
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5410
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcuc uacaccggug     1680

acccugagca aggaccagcu cuccgggaua aacaauaucg cuuucucaaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5411
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5411
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5412
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5412
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagauc cacaccugug     1680

acccuuagca aggaccagcu cucuggaauu aacaauaucg cguucuccaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5413
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5413
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu uaaagccaac gcaauaacaa caauucucac ugcugucacc      180

uucugcuucg ccucaggcca aaacauaacg gaagaauuuu accaaucaac augcucugca      240

guauccaaag gcuaccuauc ugcucuaaga acagguuggu auacaucagu aauaaccaua      300

gaacuaucaa acauaaaaga aaauaaaugc aacggaacag acgcaaaagu uaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guuaccgaac uacaacuacu uaugcaaucc      420

acucccgcca cuggaucagg aucagcaaua gcaucaggag ucgcaguaug uaaagucuua      480

caccucgaag gcgaagucaa uaaaaucaaa uccgcauuac uauccacaaa caaagcaguc      540

guaucccuaa gcggaugcgg aguaucagua cuaacauuua aaguacuaga ccuaaaaaau      600

uacaucgaua aacaacuauu accuauauua aacaaacaau ccugcuccau uucaaauauc      660

gaaaccguaa uagaauuuca acaaaaaaac aacagauuac uagaaauaac aagagaauuu      720

uccguaaaug cuggcguaac aacaccagua uccacauaca ugcucacaaa cuccgaacua      780

cuaucacuaa uaaaugacau gcccauaaca aacgaucaaa aaaaacuaau gucaaauaau      840

guacaaauag uaagacaaca aagcuacucc aucaugugua uaauaaaaga agaaguacua      900

gcauacguag uucaacuacc acuuuacggc guaaucgaca ccccuugcug gaaacuacac      960

accuccccuc uaugcaccac aaacacaaaa gaagguucca acauaugccu uaccagaaca     1020

gacagaggcu gguauugcga caacgcagga ucaguuucau uuuuuccaca agcugaaaca     1080

ugcaaaguac aaucaaacag agucuucugc gacacaauga acucaagaac ucuacccuca     1140

gaaguaaacc uauguaacgu agacauuuuc aaccccaaau acgacugcaa aauuaugaca     1200

ucaaaaacag acguuucauc aucaguuauc accucauuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucaaauaaa ugcagaggaa uaauaaaaac uuucuccaac     1320

ggaugcgacu acguuucaaa caaaggugua gacacuguau caguaggaaa cacacuauau     1380

uacguaaaua aacaagaagg aaaaucacuu uaugucaaag gagaaccaau aaucaauuuc     1440

uacgacccau uaguauuccc aucagacgaa uuugaugcuu caauaucaca aguaaacgaa     1500

aaaauaaauc aaucacucgc auuuauacga aaaucagacg aacuacuaca caauguaaac     1560

gcaggcaaau caacaacaaa cauaaugaua acaacaauaa ucauuguaau aauaguaaua     1620

cuucuaucuc uaauagcagu aggauuacuc cucuacugca aagcaagauc aaccccugua     1680

acacuaucaa aagaccaacu uucagguaua aauaauauag cuuuuuccaa uuaaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5414
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5414
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccuaauccu caaagccaac gcgaucacua caauccucac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaggaguucu accaaucaac cugcuccgcc      240

guaucaaaag gauaccuaag cgcccuacgg accggcuggu acacaucugu caucaccauc      300

gaacuaucaa acaucaaaga aaacaaaugc aacggaaccg acgcaaaagu caaacugauu      360

aaacaagaac uagacaaaua caaaaacgca gucaccgaac ugcaauuacu caugcaaagc      420

acaccggcca ccggcucagg cagcgccauc gccuccggcg ucgccgucug caaaguucuc      480

caccucgagg gcgaagucaa caaaauaaaa ucugcccucc ucuccaccaa caaagccguc      540

gucucccuca gcggcugcgg agucuccguc cucaccuuca aaguucucga ucucaagaac      600

uauauugaca aacaacuucu acccauacuc aacaaacaaa gcugcagcau auccaacauc      660

gaaaccguca ucgaguucca acaaaagaac aaccgccucc ucgaaauaac ccgcgaguuc      720

agcguuaacg ccggagucac uaccccuguc uccaccuaca ugcucaccaa cuccgaacuc      780

cuaucacuaa ucaacgacau gcccauaacc aacgaccaga agaaacucau guccaacaac      840

guccaaauug uccgacaaca aagcuacucc auaaugugca uaauaaaaga ggaaguccuc      900

gccuacgucg uacaacugcc ccuuuauggc guaaucgaca cacccugcug gaaacuccac      960

acgucacccc ucugcaccac caacacaaaa gaaggcucga acaucugccu aacacggacu     1020

gaccgcggcu gguacugcga caacgccggc uccgucagcu ucuucccaca agccgaaacc     1080

ugcaaaguac aauccaaccg aguauucugc gacaccauga acuccagaac ccuccccuca     1140

gaggucaacc ugugcaacgu agacaucuuc aaccccaaau acgacugcaa aauaaugacc     1200

ucaaaaacag acgucuccuc uuccguaauc accagccucg gagccaucgu cagcugcuac     1260

ggcaaaacca aaugcaccgc cucaaacaaa ugccgcggca ucaucaaaac auucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacacaguaa gcguaggcaa cacacuguac     1380

uacgucaaca aacaagaggg aaaaucacuc uacgucaaag gagaacccau aaucaacuuc     1440

uacgaccccc ucguuuuccc cagcgacgag uucgacgcca gcauauccca agucaacgag     1500

aaaauuaacc aaucccuagc auucauccga aaaucugacg aacugcucca caacgucaac     1560

gcgggaaaau caacaaccaa cauaaugaua accacaauca uaauagucau caucguaauc     1620

cuccucagcc uaaucgcugu cggccuccuc cucuacugca aagcccguuc caccccaguc     1680

acacuuucca aggaccaacu aagcggaaua aacaacaucg cguucucaaa cuaaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  5415
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5415
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5416
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5416
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5417
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5417
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5418
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5418
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggg     1680

auaaacaaua ucgcuuucuc aaacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5419
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5419
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5420
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5420
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucugga     1680

auuaacaaua ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5421
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5421
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuuaaagcc      120

aacgcaauaa caacaauucu cacugcuguc accuucugcu ucgccucagg ccaaaacaua      180

acggaagaau uuuaccaauc aacaugcucu gcaguaucca aaggcuaccu aucugcucua      240

agaacagguu gguauacauc aguaauaacc auagaacuau caaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguuaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguuaccg aacuacaacu acuuaugcaa uccacucccg ccacuggauc aggaucagca      420

auagcaucag gagucgcagu auguaaaguc uuacaccucg aaggcgaagu caauaaaauc      480

aaauccgcau uacuauccac aaacaaagca gucguauccc uaagcggaug cggaguauca      540

guacuaacau uuaaaguacu agaccuaaaa aauuacaucg auaaacaacu auuaccuaua      600

uuaaacaaac aauccugcuc cauuucaaau aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagau uacuagaaau aacaagagaa uuuuccguaa augcuggcgu aacaacacca      720

guauccacau acaugcucac aaacuccgaa cuacuaucac uaauaaauga caugcccaua      780

acaaacgauc aaaaaaaacu aaugucaaau aauguacaaa uaguaagaca acaaagcuac      840

uccaucaugu guauaauaaa agaagaagua cuagcauacg uaguucaacu accacuuuac      900

ggcguaaucg acaccccuug cuggaaacua cacaccuccc cucuaugcac cacaaacaca      960

aaagaagguu ccaacauaug ccuuaccaga acagacagag gcugguauug cgacaacgca     1020

ggaucaguuu cauuuuuucc acaagcugaa acaugcaaag uacaaucaaa cagagucuuc     1080

ugcgacacaa ugaacucaag aacucuaccc ucagaaguaa accuauguaa cguagacauu     1140

uucaacccca aauacgacug caaaauuaug acaucaaaaa cagacguuuc aucaucaguu     1200

aucaccucau uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucaaau     1260

aaaugcagag gaauaauaaa aacuuucucc aacggaugcg acuacguuuc aaacaaaggu     1320

guagacacug uaucaguagg aaacacacua uauuacguaa auaaacaaga aggaaaauca     1380

cuuuauguca aaggagaacc aauaaucaau uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug cuucaauauc acaaguaaac gaaaaaauaa aucaaucacu cgcauuuaua     1500

cgaaaaucag acgaacuacu acacaaugua aacgcaggca aaucaacaac aaacauaaug     1560

auaacaacaa uaaucauugu aauaauagua auacuucuau cucuaauagc aguaggauua     1620

cuccucuacu gcaaagcaag aucaaccccu guaacacuau caaaagacca acuuucaggu     1680

auaaauaaua uagcuuuuuc caauuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5422
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5422
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccuaau ccucaaagcc      120

aacgcgauca cuacaauccu cacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaggagu ucuaccaauc aaccugcucc gccguaucaa aaggauaccu aagcgcccua      240

cggaccggcu gguacacauc ugucaucacc aucgaacuau caaacaucaa agaaaacaaa      300

ugcaacggaa ccgacgcaaa agucaaacug auuaaacaag aacuagacaa auacaaaaac      360

gcagucaccg aacugcaauu acucaugcaa agcacaccgg ccaccggcuc aggcagcgcc      420

aucgccuccg gcgucgccgu cugcaaaguu cuccaccucg agggcgaagu caacaaaaua      480

aaaucugccc uccucuccac caacaaagcc gucgucuccc ucagcggcug cggagucucc      540

guccucaccu ucaaaguucu cgaucucaag aacuauauug acaaacaacu ucuacccaua      600

cucaacaaac aaagcugcag cauauccaac aucgaaaccg ucaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau aacccgcgag uucagcguua acgccggagu cacuaccccu      720

gucuccaccu acaugcucac caacuccgaa cuccuaucac uaaucaacga caugcccaua      780

accaacgacc agaagaaacu cauguccaac aacguccaaa uuguccgaca acaaagcuac      840

uccauaaugu gcauaauaaa agaggaaguc cucgccuacg ucguacaacu gccccuuuau      900

ggcguaaucg acacacccug cuggaaacuc cacacgucac cccucugcac caccaacaca      960

aaagaaggcu cgaacaucug ccuaacacgg acugaccgcg gcugguacug cgacaacgcc     1020

ggcuccguca gcuucuuccc acaagccgaa accugcaaag uacaauccaa ccgaguauuc     1080

ugcgacacca ugaacuccag aacccucccc ucagagguca accugugcaa cguagacauc     1140

uucaacccca aauacgacug caaaauaaug accucaaaaa cagacgucuc cucuuccgua     1200

aucaccagcc ucggagccau cgucagcugc uacggcaaaa ccaaaugcac cgccucaaac     1260

aaaugccgcg gcaucaucaa aacauucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag uaagcguagg caacacacug uacuacguca acaaacaaga gggaaaauca     1380

cucuacguca aaggagaacc cauaaucaac uucuacgacc cccucguuuu ccccagcgac     1440

gaguucgacg ccagcauauc ccaagucaac gagaaaauua accaaucccu agcauucauc     1500

cgaaaaucug acgaacugcu ccacaacguc aacgcgggaa aaucaacaac caacauaaug     1560

auaaccacaa ucauaauagu caucaucgua auccuccuca gccuaaucgc ugucggccuc     1620

cuccucuacu gcaaagcccg uuccacccca gucacacuuu ccaaggacca acuaagcgga     1680

auaaacaaca ucgcguucuc aaacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5423
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5423
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5424
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5424
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccgguc caccccggug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5425
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5425
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5426
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5426
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcuc uacaccggug     1680

acccugagca aggaccagcu cuccgggaua aacaauaucg cuuucucaaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5427
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5427
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5428
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5428
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagauc cacaccugug     1680

acccuuagca aggaccagcu cucuggaauu aacaauaucg cguucuccaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5429
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5429
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu uaaagccaac gcaauaacaa caauucucac ugcugucacc      180

uucugcuucg ccucaggcca aaacauaacg gaagaauuuu accaaucaac augcucugca      240

guauccaaag gcuaccuauc ugcucuaaga acagguuggu auacaucagu aauaaccaua      300

gaacuaucaa acauaaaaga aaauaaaugc aacggaacag acgcaaaagu uaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guuaccgaac uacaacuacu uaugcaaucc      420

acucccgcca cuggaucagg aucagcaaua gcaucaggag ucgcaguaug uaaagucuua      480

caccucgaag gcgaagucaa uaaaaucaaa uccgcauuac uauccacaaa caaagcaguc      540

guaucccuaa gcggaugcgg aguaucagua cuaacauuua aaguacuaga ccuaaaaaau      600

uacaucgaua aacaacuauu accuauauua aacaaacaau ccugcuccau uucaaauauc      660

gaaaccguaa uagaauuuca acaaaaaaac aacagauuac uagaaauaac aagagaauuu      720

uccguaaaug cuggcguaac aacaccagua uccacauaca ugcucacaaa cuccgaacua      780

cuaucacuaa uaaaugacau gcccauaaca aacgaucaaa aaaaacuaau gucaaauaau      840

guacaaauag uaagacaaca aagcuacucc aucaugugua uaauaaaaga agaaguacua      900

gcauacguag uucaacuacc acuuuacggc guaaucgaca ccccuugcug gaaacuacac      960

accuccccuc uaugcaccac aaacacaaaa gaagguucca acauaugccu uaccagaaca     1020

gacagaggcu gguauugcga caacgcagga ucaguuucau uuuuuccaca agcugaaaca     1080

ugcaaaguac aaucaaacag agucuucugc gacacaauga acucaagaac ucuacccuca     1140

gaaguaaacc uauguaacgu agacauuuuc aaccccaaau acgacugcaa aauuaugaca     1200

ucaaaaacag acguuucauc aucaguuauc accucauuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucaaauaaa ugcagaggaa uaauaaaaac uuucuccaac     1320

ggaugcgacu acguuucaaa caaaggugua gacacuguau caguaggaaa cacacuauau     1380

uacguaaaua aacaagaagg aaaaucacuu uaugucaaag gagaaccaau aaucaauuuc     1440

uacgacccau uaguauuccc aucagacgaa uuugaugcuu caauaucaca aguaaacgaa     1500

aaaauaaauc aaucacucgc auuuauacga aaaucagacg aacuacuaca caauguaaac     1560

gcaggcaaau caacaacaaa cauaaugaua acaacaauaa ucauuguaau aauaguaaua     1620

cuucuaucuc uaauagcagu aggauuacuc cucuacugca aagcaagauc aaccccugua     1680

acacuaucaa aagaccaacu uucagguaua aauaauauag cuuuuuccaa uuaaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5430
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5430
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccuaauccu caaagccaac gcgaucacua caauccucac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaggaguucu accaaucaac cugcuccgcc      240

guaucaaaag gauaccuaag cgcccuacgg accggcuggu acacaucugu caucaccauc      300

gaacuaucaa acaucaaaga aaacaaaugc aacggaaccg acgcaaaagu caaacugauu      360

aaacaagaac uagacaaaua caaaaacgca gucaccgaac ugcaauuacu caugcaaagc      420

acaccggcca ccggcucagg cagcgccauc gccuccggcg ucgccgucug caaaguucuc      480

caccucgagg gcgaagucaa caaaauaaaa ucugcccucc ucuccaccaa caaagccguc      540

gucucccuca gcggcugcgg agucuccguc cucaccuuca aaguucucga ucucaagaac      600

uauauugaca aacaacuucu acccauacuc aacaaacaaa gcugcagcau auccaacauc      660

gaaaccguca ucgaguucca acaaaagaac aaccgccucc ucgaaauaac ccgcgaguuc      720

agcguuaacg ccggagucac uaccccuguc uccaccuaca ugcucaccaa cuccgaacuc      780

cuaucacuaa ucaacgacau gcccauaacc aacgaccaga agaaacucau guccaacaac      840

guccaaauug uccgacaaca aagcuacucc auaaugugca uaauaaaaga ggaaguccuc      900

gccuacgucg uacaacugcc ccuuuauggc guaaucgaca cacccugcug gaaacuccac      960

acgucacccc ucugcaccac caacacaaaa gaaggcucga acaucugccu aacacggacu     1020

gaccgcggcu gguacugcga caacgccggc uccgucagcu ucuucccaca agccgaaacc     1080

ugcaaaguac aauccaaccg aguauucugc gacaccauga acuccagaac ccuccccuca     1140

gaggucaacc ugugcaacgu agacaucuuc aaccccaaau acgacugcaa aauaaugacc     1200

ucaaaaacag acgucuccuc uuccguaauc accagccucg gagccaucgu cagcugcuac     1260

ggcaaaacca aaugcaccgc cucaaacaaa ugccgcggca ucaucaaaac auucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacacaguaa gcguaggcaa cacacuguac     1380

uacgucaaca aacaagaggg aaaaucacuc uacgucaaag gagaacccau aaucaacuuc     1440

uacgaccccc ucguuuuccc cagcgacgag uucgacgcca gcauauccca agucaacgag     1500

aaaauuaacc aaucccuagc auucauccga aaaucugacg aacugcucca caacgucaac     1560

gcgggaaaau caacaaccaa cauaaugaua accacaauca uaauagucau caucguaauc     1620

cuccucagcc uaaucgcugu cggccuccuc cucuacugca aagcccguuc caccccaguc     1680

acacuuucca aggaccaacu aagcggaaua aacaacaucg cguucucaaa cuaaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  5431
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5431
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5432
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5432
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5433
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5433
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5434
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5434
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggg     1680

auaaacaaua ucgcuuucuc aaacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5435
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5435
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5436
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5436
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucugga     1680

auuaacaaua ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5437
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5437
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuuaaagcc      120

aacgcaauaa caacaauucu cacugcuguc accuucugcu ucgccucagg ccaaaacaua      180

acggaagaau uuuaccaauc aacaugcucu gcaguaucca aaggcuaccu aucugcucua      240

agaacagguu gguauacauc aguaauaacc auagaacuau caaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguuaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguuaccg aacuacaacu acuuaugcaa uccacucccg ccacuggauc aggaucagca      420

auagcaucag gagucgcagu auguaaaguc uuacaccucg aaggcgaagu caauaaaauc      480

aaauccgcau uacuauccac aaacaaagca gucguauccc uaagcggaug cggaguauca      540

guacuaacau uuaaaguacu agaccuaaaa aauuacaucg auaaacaacu auuaccuaua      600

uuaaacaaac aauccugcuc cauuucaaau aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagau uacuagaaau aacaagagaa uuuuccguaa augcuggcgu aacaacacca      720

guauccacau acaugcucac aaacuccgaa cuacuaucac uaauaaauga caugcccaua      780

acaaacgauc aaaaaaaacu aaugucaaau aauguacaaa uaguaagaca acaaagcuac      840

uccaucaugu guauaauaaa agaagaagua cuagcauacg uaguucaacu accacuuuac      900

ggcguaaucg acaccccuug cuggaaacua cacaccuccc cucuaugcac cacaaacaca      960

aaagaagguu ccaacauaug ccuuaccaga acagacagag gcugguauug cgacaacgca     1020

ggaucaguuu cauuuuuucc acaagcugaa acaugcaaag uacaaucaaa cagagucuuc     1080

ugcgacacaa ugaacucaag aacucuaccc ucagaaguaa accuauguaa cguagacauu     1140

uucaacccca aauacgacug caaaauuaug acaucaaaaa cagacguuuc aucaucaguu     1200

aucaccucau uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucaaau     1260

aaaugcagag gaauaauaaa aacuuucucc aacggaugcg acuacguuuc aaacaaaggu     1320

guagacacug uaucaguagg aaacacacua uauuacguaa auaaacaaga aggaaaauca     1380

cuuuauguca aaggagaacc aauaaucaau uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug cuucaauauc acaaguaaac gaaaaaauaa aucaaucacu cgcauuuaua     1500

cgaaaaucag acgaacuacu acacaaugua aacgcaggca aaucaacaac aaacauaaug     1560

auaacaacaa uaaucauugu aauaauagua auacuucuau cucuaauagc aguaggauua     1620

cuccucuacu gcaaagcaag aucaaccccu guaacacuau caaaagacca acuuucaggu     1680

auaaauaaua uagcuuuuuc caauuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5438
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5438
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccuaau ccucaaagcc      120

aacgcgauca cuacaauccu cacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaggagu ucuaccaauc aaccugcucc gccguaucaa aaggauaccu aagcgcccua      240

cggaccggcu gguacacauc ugucaucacc aucgaacuau caaacaucaa agaaaacaaa      300

ugcaacggaa ccgacgcaaa agucaaacug auuaaacaag aacuagacaa auacaaaaac      360

gcagucaccg aacugcaauu acucaugcaa agcacaccgg ccaccggcuc aggcagcgcc      420

aucgccuccg gcgucgccgu cugcaaaguu cuccaccucg agggcgaagu caacaaaaua      480

aaaucugccc uccucuccac caacaaagcc gucgucuccc ucagcggcug cggagucucc      540

guccucaccu ucaaaguucu cgaucucaag aacuauauug acaaacaacu ucuacccaua      600

cucaacaaac aaagcugcag cauauccaac aucgaaaccg ucaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau aacccgcgag uucagcguua acgccggagu cacuaccccu      720

gucuccaccu acaugcucac caacuccgaa cuccuaucac uaaucaacga caugcccaua      780

accaacgacc agaagaaacu cauguccaac aacguccaaa uuguccgaca acaaagcuac      840

uccauaaugu gcauaauaaa agaggaaguc cucgccuacg ucguacaacu gccccuuuau      900

ggcguaaucg acacacccug cuggaaacuc cacacgucac cccucugcac caccaacaca      960

aaagaaggcu cgaacaucug ccuaacacgg acugaccgcg gcugguacug cgacaacgcc     1020

ggcuccguca gcuucuuccc acaagccgaa accugcaaag uacaauccaa ccgaguauuc     1080

ugcgacacca ugaacuccag aacccucccc ucagagguca accugugcaa cguagacauc     1140

uucaacccca aauacgacug caaaauaaug accucaaaaa cagacgucuc cucuuccgua     1200

aucaccagcc ucggagccau cgucagcugc uacggcaaaa ccaaaugcac cgccucaaac     1260

aaaugccgcg gcaucaucaa aacauucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag uaagcguagg caacacacug uacuacguca acaaacaaga gggaaaauca     1380

cucuacguca aaggagaacc cauaaucaac uucuacgacc cccucguuuu ccccagcgac     1440

gaguucgacg ccagcauauc ccaagucaac gagaaaauua accaaucccu agcauucauc     1500

cgaaaaucug acgaacugcu ccacaacguc aacgcgggaa aaucaacaac caacauaaug     1560

auaaccacaa ucauaauagu caucaucgua auccuccuca gccuaaucgc ugucggccuc     1620

cuccucuacu gcaaagcccg uuccacccca gucacacuuu ccaaggacca acuaagcgga     1680

auaaacaaca ucgcguucuc aaacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  5439
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5439
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5440
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5440
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5441
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5441
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5442
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5442
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggg     1680

auaaacaaua ucgcuuucuc aaacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5443
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5443
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5444
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5444
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucugga     1680

auuaacaaua ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5445
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5445
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuuaaagcc      120

aacgcaauaa caacaauucu cacugcuguc accuucugcu ucgccucagg ccaaaacaua      180

acggaagaau uuuaccaauc aacaugcucu gcaguaucca aaggcuaccu aucugcucua      240

agaacagguu gguauacauc aguaauaacc auagaacuau caaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguuaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguuaccg aacuacaacu acuuaugcaa uccacucccg ccacuggauc aggaucagca      420

auagcaucag gagucgcagu auguaaaguc uuacaccucg aaggcgaagu caauaaaauc      480

aaauccgcau uacuauccac aaacaaagca gucguauccc uaagcggaug cggaguauca      540

guacuaacau uuaaaguacu agaccuaaaa aauuacaucg auaaacaacu auuaccuaua      600

uuaaacaaac aauccugcuc cauuucaaau aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagau uacuagaaau aacaagagaa uuuuccguaa augcuggcgu aacaacacca      720

guauccacau acaugcucac aaacuccgaa cuacuaucac uaauaaauga caugcccaua      780

acaaacgauc aaaaaaaacu aaugucaaau aauguacaaa uaguaagaca acaaagcuac      840

uccaucaugu guauaauaaa agaagaagua cuagcauacg uaguucaacu accacuuuac      900

ggcguaaucg acaccccuug cuggaaacua cacaccuccc cucuaugcac cacaaacaca      960

aaagaagguu ccaacauaug ccuuaccaga acagacagag gcugguauug cgacaacgca     1020

ggaucaguuu cauuuuuucc acaagcugaa acaugcaaag uacaaucaaa cagagucuuc     1080

ugcgacacaa ugaacucaag aacucuaccc ucagaaguaa accuauguaa cguagacauu     1140

uucaacccca aauacgacug caaaauuaug acaucaaaaa cagacguuuc aucaucaguu     1200

aucaccucau uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucaaau     1260

aaaugcagag gaauaauaaa aacuuucucc aacggaugcg acuacguuuc aaacaaaggu     1320

guagacacug uaucaguagg aaacacacua uauuacguaa auaaacaaga aggaaaauca     1380

cuuuauguca aaggagaacc aauaaucaau uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug cuucaauauc acaaguaaac gaaaaaauaa aucaaucacu cgcauuuaua     1500

cgaaaaucag acgaacuacu acacaaugua aacgcaggca aaucaacaac aaacauaaug     1560

auaacaacaa uaaucauugu aauaauagua auacuucuau cucuaauagc aguaggauua     1620

cuccucuacu gcaaagcaag aucaaccccu guaacacuau caaaagacca acuuucaggu     1680

auaaauaaua uagcuuuuuc caauuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5446
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5446
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccuaau ccucaaagcc      120

aacgcgauca cuacaauccu cacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaggagu ucuaccaauc aaccugcucc gccguaucaa aaggauaccu aagcgcccua      240

cggaccggcu gguacacauc ugucaucacc aucgaacuau caaacaucaa agaaaacaaa      300

ugcaacggaa ccgacgcaaa agucaaacug auuaaacaag aacuagacaa auacaaaaac      360

gcagucaccg aacugcaauu acucaugcaa agcacaccgg ccaccggcuc aggcagcgcc      420

aucgccuccg gcgucgccgu cugcaaaguu cuccaccucg agggcgaagu caacaaaaua      480

aaaucugccc uccucuccac caacaaagcc gucgucuccc ucagcggcug cggagucucc      540

guccucaccu ucaaaguucu cgaucucaag aacuauauug acaaacaacu ucuacccaua      600

cucaacaaac aaagcugcag cauauccaac aucgaaaccg ucaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau aacccgcgag uucagcguua acgccggagu cacuaccccu      720

gucuccaccu acaugcucac caacuccgaa cuccuaucac uaaucaacga caugcccaua      780

accaacgacc agaagaaacu cauguccaac aacguccaaa uuguccgaca acaaagcuac      840

uccauaaugu gcauaauaaa agaggaaguc cucgccuacg ucguacaacu gccccuuuau      900

ggcguaaucg acacacccug cuggaaacuc cacacgucac cccucugcac caccaacaca      960

aaagaaggcu cgaacaucug ccuaacacgg acugaccgcg gcugguacug cgacaacgcc     1020

ggcuccguca gcuucuuccc acaagccgaa accugcaaag uacaauccaa ccgaguauuc     1080

ugcgacacca ugaacuccag aacccucccc ucagagguca accugugcaa cguagacauc     1140

uucaacccca aauacgacug caaaauaaug accucaaaaa cagacgucuc cucuuccgua     1200

aucaccagcc ucggagccau cgucagcugc uacggcaaaa ccaaaugcac cgccucaaac     1260

aaaugccgcg gcaucaucaa aacauucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag uaagcguagg caacacacug uacuacguca acaaacaaga gggaaaauca     1380

cucuacguca aaggagaacc cauaaucaac uucuacgacc cccucguuuu ccccagcgac     1440

gaguucgacg ccagcauauc ccaagucaac gagaaaauua accaaucccu agcauucauc     1500

cgaaaaucug acgaacugcu ccacaacguc aacgcgggaa aaucaacaac caacauaaug     1560

auaaccacaa ucauaauagu caucaucgua auccuccuca gccuaaucgc ugucggccuc     1620

cuccucuacu gcaaagcccg uuccacccca gucacacuuu ccaaggacca acuaagcgga     1680

auaaacaaca ucgcguucuc aaacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  5447
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5447
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5448
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5448
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccgguccac cccggugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5449
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5449
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5450
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5450
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcucuac accggugacc cugagcaagg accagcucuc cgggauaaac     1680

aauaucgcuu ucucaaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5451
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5451
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5452
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5452
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagauccac accugugacc cuuagcaagg accagcucuc uggaauuaac     1680

aauaucgcgu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5453
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5453
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuuaa agccaacgca      120

auaacaacaa uucucacugc ugucaccuuc ugcuucgccu caggccaaaa cauaacggaa      180

gaauuuuacc aaucaacaug cucugcagua uccaaaggcu accuaucugc ucuaagaaca      240

gguugguaua caucaguaau aaccauagaa cuaucaaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguuaa acucauaaaa caagaacuag acaaauauaa aaacgcaguu      360

accgaacuac aacuacuuau gcaauccacu cccgccacug gaucaggauc agcaauagca      420

ucaggagucg caguauguaa agucuuacac cucgaaggcg aagucaauaa aaucaaaucc      480

gcauuacuau ccacaaacaa agcagucgua ucccuaagcg gaugcggagu aucaguacua      540

acauuuaaag uacuagaccu aaaaaauuac aucgauaaac aacuauuacc uauauuaaac      600

aaacaauccu gcuccauuuc aaauaucgaa accguaauag aauuucaaca aaaaaacaac      660

agauuacuag aaauaacaag agaauuuucc guaaaugcug gcguaacaac accaguaucc      720

acauacaugc ucacaaacuc cgaacuacua ucacuaauaa augacaugcc cauaacaaac      780

gaucaaaaaa aacuaauguc aaauaaugua caaauaguaa gacaacaaag cuacuccauc      840

auguguauaa uaaaagaaga aguacuagca uacguaguuc aacuaccacu uuacggcgua      900

aucgacaccc cuugcuggaa acuacacacc uccccucuau gcaccacaaa cacaaaagaa      960

gguuccaaca uaugccuuac cagaacagac agaggcuggu auugcgacaa cgcaggauca     1020

guuucauuuu uuccacaagc ugaaacaugc aaaguacaau caaacagagu cuucugcgac     1080

acaaugaacu caagaacucu acccucagaa guaaaccuau guaacguaga cauuuucaac     1140

cccaaauacg acugcaaaau uaugacauca aaaacagacg uuucaucauc aguuaucacc     1200

ucauuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc aaauaaaugc     1260

agaggaauaa uaaaaacuuu cuccaacgga ugcgacuacg uuucaaacaa agguguagac     1320

acuguaucag uaggaaacac acuauauuac guaaauaaac aagaaggaaa aucacuuuau     1380

gucaaaggag aaccaauaau caauuucuac gacccauuag uauucccauc agacgaauuu     1440

gaugcuucaa uaucacaagu aaacgaaaaa auaaaucaau cacucgcauu uauacgaaaa     1500

ucagacgaac uacuacacaa uguaaacgca ggcaaaucaa caacaaacau aaugauaaca     1560

acaauaauca uuguaauaau aguaauacuu cuaucucuaa uagcaguagg auuacuccuc     1620

uacugcaaag caagaucaac cccuguaaca cuaucaaaag accaacuuuc agguauaaau     1680

aauauagcuu uuuccaauua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5454
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5454
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc uaauccucaa agccaacgcg      120

aucacuacaa uccucacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgag      180

gaguucuacc aaucaaccug cuccgccgua ucaaaaggau accuaagcgc ccuacggacc      240

ggcugguaca caucugucau caccaucgaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggaaccgacg caaaagucaa acugauuaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaacugc aauuacucau gcaaagcaca ccggccaccg gcucaggcag cgccaucgcc      420

uccggcgucg ccgucugcaa aguucuccac cucgagggcg aagucaacaa aauaaaaucu      480

gcccuccucu ccaccaacaa agccgucguc ucccucagcg gcugcggagu cuccguccuc      540

accuucaaag uucucgaucu caagaacuau auugacaaac aacuucuacc cauacucaac      600

aaacaaagcu gcagcauauc caacaucgaa accgucaucg aguuccaaca aaagaacaac      660

cgccuccucg aaauaacccg cgaguucagc guuaacgccg gagucacuac cccugucucc      720

accuacaugc ucaccaacuc cgaacuccua ucacuaauca acgacaugcc cauaaccaac      780

gaccagaaga aacucauguc caacaacguc caaauugucc gacaacaaag cuacuccaua      840

augugcauaa uaaaagagga aguccucgcc uacgucguac aacugccccu uuauggcgua      900

aucgacacac ccugcuggaa acuccacacg ucaccccucu gcaccaccaa cacaaaagaa      960

ggcucgaaca ucugccuaac acggacugac cgcggcuggu acugcgacaa cgccggcucc     1020

gucagcuucu ucccacaagc cgaaaccugc aaaguacaau ccaaccgagu auucugcgac     1080

accaugaacu ccagaacccu ccccucagag gucaaccugu gcaacguaga caucuucaac     1140

cccaaauacg acugcaaaau aaugaccuca aaaacagacg ucuccucuuc cguaaucacc     1200

agccucggag ccaucgucag cugcuacggc aaaaccaaau gcaccgccuc aaacaaaugc     1260

cgcggcauca ucaaaacauu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

acaguaagcg uaggcaacac acuguacuac gucaacaaac aagagggaaa aucacucuac     1380

gucaaaggag aacccauaau caacuucuac gacccccucg uuuuccccag cgacgaguuc     1440

gacgccagca uaucccaagu caacgagaaa auuaaccaau cccuagcauu cauccgaaaa     1500

ucugacgaac ugcuccacaa cgucaacgcg ggaaaaucaa caaccaacau aaugauaacc     1560

acaaucauaa uagucaucau cguaauccuc cucagccuaa ucgcugucgg ccuccuccuc     1620

uacugcaaag cccguuccac cccagucaca cuuuccaagg accaacuaag cggaauaaac     1680

aacaucgcgu ucucaaacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5455
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5455
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5456
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5456
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccgguccacc ccggugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5457
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5457
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5458
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5458
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcucuaca ccggugaccc ugagcaagga ccagcucucc     1680

gggauaaaca auaucgcuuu cucaaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5459
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5459
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5460
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5460
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagauccaca ccugugaccc uuagcaagga ccagcucucu     1680

ggaauuaaca auaucgcguu cuccaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5461
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5461
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuuaaa      120

gccaacgcaa uaacaacaau ucucacugcu gucaccuucu gcuucgccuc aggccaaaac      180

auaacggaag aauuuuacca aucaacaugc ucugcaguau ccaaaggcua ccuaucugcu      240

cuaagaacag guugguauac aucaguaaua accauagaac uaucaaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguuaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguua ccgaacuaca acuacuuaug caauccacuc ccgccacugg aucaggauca      420

gcaauagcau caggagucgc aguauguaaa gucuuacacc ucgaaggcga agucaauaaa      480

aucaaauccg cauuacuauc cacaaacaaa gcagucguau cccuaagcgg augcggagua      540

ucaguacuaa cauuuaaagu acuagaccua aaaaauuaca ucgauaaaca acuauuaccu      600

auauuaaaca aacaauccug cuccauuuca aauaucgaaa ccguaauaga auuucaacaa      660

aaaaacaaca gauuacuaga aauaacaaga gaauuuuccg uaaaugcugg cguaacaaca      720

ccaguaucca cauacaugcu cacaaacucc gaacuacuau cacuaauaaa ugacaugccc      780

auaacaaacg aucaaaaaaa acuaauguca aauaauguac aaauaguaag acaacaaagc      840

uacuccauca uguguauaau aaaagaagaa guacuagcau acguaguuca acuaccacuu      900

uacggcguaa ucgacacccc uugcuggaaa cuacacaccu ccccucuaug caccacaaac      960

acaaaagaag guuccaacau augccuuacc agaacagaca gaggcuggua uugcgacaac     1020

gcaggaucag uuucauuuuu uccacaagcu gaaacaugca aaguacaauc aaacagaguc     1080

uucugcgaca caaugaacuc aagaacucua cccucagaag uaaaccuaug uaacguagac     1140

auuuucaacc ccaaauacga cugcaaaauu augacaucaa aaacagacgu uucaucauca     1200

guuaucaccu cauuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccuca     1260

aauaaaugca gaggaauaau aaaaacuuuc uccaacggau gcgacuacgu uucaaacaaa     1320

gguguagaca cuguaucagu aggaaacaca cuauauuacg uaaauaaaca agaaggaaaa     1380

ucacuuuaug ucaaaggaga accaauaauc aauuucuacg acccauuagu auucccauca     1440

gacgaauuug augcuucaau aucacaagua aacgaaaaaa uaaaucaauc acucgcauuu     1500

auacgaaaau cagacgaacu acuacacaau guaaacgcag gcaaaucaac aacaaacaua     1560

augauaacaa caauaaucau uguaauaaua guaauacuuc uaucucuaau agcaguagga     1620

uuacuccucu acugcaaagc aagaucaacc ccuguaacac uaucaaaaga ccaacuuuca     1680

gguauaaaua auauagcuuu uuccaauuaa ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5462
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5462
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu aauccucaaa      120

gccaacgcga ucacuacaau ccucacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgagg aguucuacca aucaaccugc uccgccguau caaaaggaua ccuaagcgcc      240

cuacggaccg gcugguacac aucugucauc accaucgaac uaucaaacau caaagaaaac      300

aaaugcaacg gaaccgacgc aaaagucaaa cugauuaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaacugca auuacucaug caaagcacac cggccaccgg cucaggcagc      420

gccaucgccu ccggcgucgc cgucugcaaa guucuccacc ucgagggcga agucaacaaa      480

auaaaaucug cccuccucuc caccaacaaa gccgucgucu cccucagcgg cugcggaguc      540

uccguccuca ccuucaaagu ucucgaucuc aagaacuaua uugacaaaca acuucuaccc      600

auacucaaca aacaaagcug cagcauaucc aacaucgaaa ccgucaucga guuccaacaa      660

aagaacaacc gccuccucga aauaacccgc gaguucagcg uuaacgccgg agucacuacc      720

ccugucucca ccuacaugcu caccaacucc gaacuccuau cacuaaucaa cgacaugccc      780

auaaccaacg accagaagaa acucaugucc aacaacgucc aaauuguccg acaacaaagc      840

uacuccauaa ugugcauaau aaaagaggaa guccucgccu acgucguaca acugccccuu      900

uauggcguaa ucgacacacc cugcuggaaa cuccacacgu caccccucug caccaccaac      960

acaaaagaag gcucgaacau cugccuaaca cggacugacc gcggcuggua cugcgacaac     1020

gccggcuccg ucagcuucuu cccacaagcc gaaaccugca aaguacaauc caaccgagua     1080

uucugcgaca ccaugaacuc cagaacccuc cccucagagg ucaaccugug caacguagac     1140

aucuucaacc ccaaauacga cugcaaaaua augaccucaa aaacagacgu cuccucuucc     1200

guaaucacca gccucggagc caucgucagc ugcuacggca aaaccaaaug caccgccuca     1260

aacaaaugcc gcggcaucau caaaacauuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca caguaagcgu aggcaacaca cuguacuacg ucaacaaaca agagggaaaa     1380

ucacucuacg ucaaaggaga acccauaauc aacuucuacg acccccucgu uuuccccagc     1440

gacgaguucg acgccagcau aucccaaguc aacgagaaaa uuaaccaauc ccuagcauuc     1500

auccgaaaau cugacgaacu gcuccacaac gucaacgcgg gaaaaucaac aaccaacaua     1560

augauaacca caaucauaau agucaucauc guaauccucc ucagccuaau cgcugucggc     1620

cuccuccucu acugcaaagc ccguuccacc ccagucacac uuuccaagga ccaacuaagc     1680

ggaauaaaca acaucgcguu cucaaacuaa ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  5463
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5463
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5464
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5464
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccgguccac cccggugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5465
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5465
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5466
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5466
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcucuac accggugacc cugagcaagg accagcucuc cgggauaaac     1680

aauaucgcuu ucucaaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5467
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5467
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5468
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5468
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagauccac accugugacc cuuagcaagg accagcucuc uggaauuaac     1680

aauaucgcgu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5469
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5469
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuuaa agccaacgca      120

auaacaacaa uucucacugc ugucaccuuc ugcuucgccu caggccaaaa cauaacggaa      180

gaauuuuacc aaucaacaug cucugcagua uccaaaggcu accuaucugc ucuaagaaca      240

gguugguaua caucaguaau aaccauagaa cuaucaaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguuaa acucauaaaa caagaacuag acaaauauaa aaacgcaguu      360

accgaacuac aacuacuuau gcaauccacu cccgccacug gaucaggauc agcaauagca      420

ucaggagucg caguauguaa agucuuacac cucgaaggcg aagucaauaa aaucaaaucc      480

gcauuacuau ccacaaacaa agcagucgua ucccuaagcg gaugcggagu aucaguacua      540

acauuuaaag uacuagaccu aaaaaauuac aucgauaaac aacuauuacc uauauuaaac      600

aaacaauccu gcuccauuuc aaauaucgaa accguaauag aauuucaaca aaaaaacaac      660

agauuacuag aaauaacaag agaauuuucc guaaaugcug gcguaacaac accaguaucc      720

acauacaugc ucacaaacuc cgaacuacua ucacuaauaa augacaugcc cauaacaaac      780

gaucaaaaaa aacuaauguc aaauaaugua caaauaguaa gacaacaaag cuacuccauc      840

auguguauaa uaaaagaaga aguacuagca uacguaguuc aacuaccacu uuacggcgua      900

aucgacaccc cuugcuggaa acuacacacc uccccucuau gcaccacaaa cacaaaagaa      960

gguuccaaca uaugccuuac cagaacagac agaggcuggu auugcgacaa cgcaggauca     1020

guuucauuuu uuccacaagc ugaaacaugc aaaguacaau caaacagagu cuucugcgac     1080

acaaugaacu caagaacucu acccucagaa guaaaccuau guaacguaga cauuuucaac     1140

cccaaauacg acugcaaaau uaugacauca aaaacagacg uuucaucauc aguuaucacc     1200

ucauuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc aaauaaaugc     1260

agaggaauaa uaaaaacuuu cuccaacgga ugcgacuacg uuucaaacaa agguguagac     1320

acuguaucag uaggaaacac acuauauuac guaaauaaac aagaaggaaa aucacuuuau     1380

gucaaaggag aaccaauaau caauuucuac gacccauuag uauucccauc agacgaauuu     1440

gaugcuucaa uaucacaagu aaacgaaaaa auaaaucaau cacucgcauu uauacgaaaa     1500

ucagacgaac uacuacacaa uguaaacgca ggcaaaucaa caacaaacau aaugauaaca     1560

acaauaauca uuguaauaau aguaauacuu cuaucucuaa uagcaguagg auuacuccuc     1620

uacugcaaag caagaucaac cccuguaaca cuaucaaaag accaacuuuc agguauaaau     1680

aauauagcuu uuuccaauua aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5470
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5470
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc uaauccucaa agccaacgcg      120

aucacuacaa uccucacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgag      180

gaguucuacc aaucaaccug cuccgccgua ucaaaaggau accuaagcgc ccuacggacc      240

ggcugguaca caucugucau caccaucgaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggaaccgacg caaaagucaa acugauuaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaacugc aauuacucau gcaaagcaca ccggccaccg gcucaggcag cgccaucgcc      420

uccggcgucg ccgucugcaa aguucuccac cucgagggcg aagucaacaa aauaaaaucu      480

gcccuccucu ccaccaacaa agccgucguc ucccucagcg gcugcggagu cuccguccuc      540

accuucaaag uucucgaucu caagaacuau auugacaaac aacuucuacc cauacucaac      600

aaacaaagcu gcagcauauc caacaucgaa accgucaucg aguuccaaca aaagaacaac      660

cgccuccucg aaauaacccg cgaguucagc guuaacgccg gagucacuac cccugucucc      720

accuacaugc ucaccaacuc cgaacuccua ucacuaauca acgacaugcc cauaaccaac      780

gaccagaaga aacucauguc caacaacguc caaauugucc gacaacaaag cuacuccaua      840

augugcauaa uaaaagagga aguccucgcc uacgucguac aacugccccu uuauggcgua      900

aucgacacac ccugcuggaa acuccacacg ucaccccucu gcaccaccaa cacaaaagaa      960

ggcucgaaca ucugccuaac acggacugac cgcggcuggu acugcgacaa cgccggcucc     1020

gucagcuucu ucccacaagc cgaaaccugc aaaguacaau ccaaccgagu auucugcgac     1080

accaugaacu ccagaacccu ccccucagag gucaaccugu gcaacguaga caucuucaac     1140

cccaaauacg acugcaaaau aaugaccuca aaaacagacg ucuccucuuc cguaaucacc     1200

agccucggag ccaucgucag cugcuacggc aaaaccaaau gcaccgccuc aaacaaaugc     1260

cgcggcauca ucaaaacauu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

acaguaagcg uaggcaacac acuguacuac gucaacaaac aagagggaaa aucacucuac     1380

gucaaaggag aacccauaau caacuucuac gacccccucg uuuuccccag cgacgaguuc     1440

gacgccagca uaucccaagu caacgagaaa auuaaccaau cccuagcauu cauccgaaaa     1500

ucugacgaac ugcuccacaa cgucaacgcg ggaaaaucaa caaccaacau aaugauaacc     1560

acaaucauaa uagucaucau cguaauccuc cucagccuaa ucgcugucgg ccuccuccuc     1620

uacugcaaag cccguuccac cccagucaca cuuuccaagg accaacuaag cggaauaaac     1680

aacaucgcgu ucucaaacua aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  5471
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5471
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5472
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5472
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5473
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5473
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5474
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5474
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1740

aaggaccagc ucuccgggau aaacaauauc gcuuucucaa acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5475
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5475
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5476
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5476
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1740

aaggaccagc ucucuggaau uaacaauauc gcguucucca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5477
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5477
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uuaaagccaa cgcaauaaca acaauucuca cugcugucac cuucugcuuc      240

gccucaggcc aaaacauaac ggaagaauuu uaccaaucaa caugcucugc aguauccaaa      300

ggcuaccuau cugcucuaag aacagguugg uauacaucag uaauaaccau agaacuauca      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uuaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguuaccgaa cuacaacuac uuaugcaauc cacucccgcc      480

acuggaucag gaucagcaau agcaucagga gucgcaguau guaaagucuu acaccucgaa      540

ggcgaaguca auaaaaucaa auccgcauua cuauccacaa acaaagcagu cguaucccua      600

agcggaugcg gaguaucagu acuaacauuu aaaguacuag accuaaaaaa uuacaucgau      660

aaacaacuau uaccuauauu aaacaaacaa uccugcucca uuucaaauau cgaaaccgua      720

auagaauuuc aacaaaaaaa caacagauua cuagaaauaa caagagaauu uuccguaaau      780

gcuggcguaa caacaccagu auccacauac augcucacaa acuccgaacu acuaucacua      840

auaaaugaca ugcccauaac aaacgaucaa aaaaaacuaa ugucaaauaa uguacaaaua      900

guaagacaac aaagcuacuc caucaugugu auaauaaaag aagaaguacu agcauacgua      960

guucaacuac cacuuuacgg cguaaucgac accccuugcu ggaaacuaca caccuccccu     1020

cuaugcacca caaacacaaa agaagguucc aacauaugcc uuaccagaac agacagaggc     1080

ugguauugcg acaacgcagg aucaguuuca uuuuuuccac aagcugaaac augcaaagua     1140

caaucaaaca gagucuucug cgacacaaug aacucaagaa cucuacccuc agaaguaaac     1200

cuauguaacg uagacauuuu caaccccaaa uacgacugca aaauuaugac aucaaaaaca     1260

gacguuucau caucaguuau caccucauua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucaaauaa augcagagga auaauaaaaa cuuucuccaa cggaugcgac     1380

uacguuucaa acaaaggugu agacacugua ucaguaggaa acacacuaua uuacguaaau     1440

aaacaagaag gaaaaucacu uuaugucaaa ggagaaccaa uaaucaauuu cuacgaccca     1500

uuaguauucc caucagacga auuugaugcu ucaauaucac aaguaaacga aaaaauaaau     1560

caaucacucg cauuuauacg aaaaucagac gaacuacuac acaauguaaa cgcaggcaaa     1620

ucaacaacaa acauaaugau aacaacaaua aucauuguaa uaauaguaau acuucuaucu     1680

cuaauagcag uaggauuacu ccucuacugc aaagcaagau caaccccugu aacacuauca     1740

aaagaccaac uuucagguau aaauaauaua gcuuuuucca auuaaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5478
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5478
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccuaaucc ucaaagccaa cgcgaucacu acaauccuca cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaggaguuc uaccaaucaa ccugcuccgc cguaucaaaa      300

ggauaccuaa gcgcccuacg gaccggcugg uacacaucug ucaucaccau cgaacuauca      360

aacaucaaag aaaacaaaug caacggaacc gacgcaaaag ucaaacugau uaaacaagaa      420

cuagacaaau acaaaaacgc agucaccgaa cugcaauuac ucaugcaaag cacaccggcc      480

accggcucag gcagcgccau cgccuccggc gucgccgucu gcaaaguucu ccaccucgag      540

ggcgaaguca acaaaauaaa aucugcccuc cucuccacca acaaagccgu cgucucccuc      600

agcggcugcg gagucuccgu ccucaccuuc aaaguucucg aucucaagaa cuauauugac      660

aaacaacuuc uacccauacu caacaaacaa agcugcagca uauccaacau cgaaaccguc      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauaa cccgcgaguu cagcguuaac      780

gccggaguca cuaccccugu cuccaccuac augcucacca acuccgaacu ccuaucacua      840

aucaacgaca ugcccauaac caacgaccag aagaaacuca uguccaacaa cguccaaauu      900

guccgacaac aaagcuacuc cauaaugugc auaauaaaag aggaaguccu cgccuacguc      960

guacaacugc cccuuuaugg cguaaucgac acacccugcu ggaaacucca cacgucaccc     1020

cucugcacca ccaacacaaa agaaggcucg aacaucugcc uaacacggac ugaccgcggc     1080

ugguacugcg acaacgccgg cuccgucagc uucuucccac aagccgaaac cugcaaagua     1140

caauccaacc gaguauucug cgacaccaug aacuccagaa cccuccccuc agaggucaac     1200

cugugcaacg uagacaucuu caaccccaaa uacgacugca aaauaaugac cucaaaaaca     1260

gacgucuccu cuuccguaau caccagccuc ggagccaucg ucagcugcua cggcaaaacc     1320

aaaugcaccg ccucaaacaa augccgcggc aucaucaaaa cauucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacacagua agcguaggca acacacugua cuacgucaac     1440

aaacaagagg gaaaaucacu cuacgucaaa ggagaaccca uaaucaacuu cuacgacccc     1500

cucguuuucc ccagcgacga guucgacgcc agcauauccc aagucaacga gaaaauuaac     1560

caaucccuag cauucauccg aaaaucugac gaacugcucc acaacgucaa cgcgggaaaa     1620

ucaacaacca acauaaugau aaccacaauc auaauaguca ucaucguaau ccuccucagc     1680

cuaaucgcug ucggccuccu ccucuacugc aaagcccguu ccaccccagu cacacuuucc     1740

aaggaccaac uaagcggaau aaacaacauc gcguucucaa acuaaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  5479
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5479
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5480
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5480
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

gguccacccc ggugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5481
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5481
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5482
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5482
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcucuacacc ggugacccug agcaaggacc agcucuccgg gauaaacaau aucgcuuucu     1680

caaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5483
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5483
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5484
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5484
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gauccacacc ugugacccuu agcaaggacc agcucucugg aauuaacaau aucgcguucu     1680

ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5485
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5485
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc      120

ucacugcugu caccuucugc uucgccucag gccaaaacau aacggaagaa uuuuaccaau      180

caacaugcuc ugcaguaucc aaaggcuacc uaucugcucu aagaacaggu ugguauacau      240

caguaauaac cauagaacua ucaaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguuaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac      360

uacuuaugca auccacuccc gccacuggau caggaucagc aauagcauca ggagucgcag      420

uauguaaagu cuuacaccuc gaaggcgaag ucaauaaaau caaauccgca uuacuaucca      480

caaacaaagc agucguaucc cuaagcggau gcggaguauc aguacuaaca uuuaaaguac      540

uagaccuaaa aaauuacauc gauaaacaac uauuaccuau auuaaacaaa caauccugcu      600

ccauuucaaa uaucgaaacc guaauagaau uucaacaaaa aaacaacaga uuacuagaaa      660

uaacaagaga auuuuccgua aaugcuggcg uaacaacacc aguauccaca uacaugcuca      720

caaacuccga acuacuauca cuaauaaaug acaugcccau aacaaacgau caaaaaaaac      780

uaaugucaaa uaauguacaa auaguaagac aacaaagcua cuccaucaug uguauaauaa      840

aagaagaagu acuagcauac guaguucaac uaccacuuua cggcguaauc gacaccccuu      900

gcuggaaacu acacaccucc ccucuaugca ccacaaacac aaaagaaggu uccaacauau      960

gccuuaccag aacagacaga ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc     1020

cacaagcuga aacaugcaaa guacaaucaa acagagucuu cugcgacaca augaacucaa     1080

gaacucuacc cucagaagua aaccuaugua acguagacau uuucaacccc aaauacgacu     1140

gcaaaauuau gacaucaaaa acagacguuu caucaucagu uaucaccuca uuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa     1260

aaacuuucuc caacggaugc gacuacguuu caaacaaagg uguagacacu guaucaguag     1320

gaaacacacu auauuacgua aauaaacaag aaggaaaauc acuuuauguc aaaggagaac     1380

caauaaucaa uuucuacgac ccauuaguau ucccaucaga cgaauuugau gcuucaauau     1440

cacaaguaaa cgaaaaaaua aaucaaucac ucgcauuuau acgaaaauca gacgaacuac     1500

uacacaaugu aaacgcaggc aaaucaacaa caaacauaau gauaacaaca auaaucauug     1560

uaauaauagu aauacuucua ucucuaauag caguaggauu acuccucuac ugcaaagcaa     1620

gaucaacccc uguaacacua ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu     1680

ccaauuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5486
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5486
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuaa uccucaaagc caacgcgauc acuacaaucc      120

ucacagccgu caccuucugc uucgccuccg gccaaaacau caccgaggag uucuaccaau      180

caaccugcuc cgccguauca aaaggauacc uaagcgcccu acggaccggc ugguacacau      240

cugucaucac caucgaacua ucaaacauca aagaaaacaa augcaacgga accgacgcaa      300

aagucaaacu gauuaaacaa gaacuagaca aauacaaaaa cgcagucacc gaacugcaau      360

uacucaugca aagcacaccg gccaccggcu caggcagcgc caucgccucc ggcgucgccg      420

ucugcaaagu ucuccaccuc gagggcgaag ucaacaaaau aaaaucugcc cuccucucca      480

ccaacaaagc cgucgucucc cucagcggcu gcggagucuc cguccucacc uucaaaguuc      540

ucgaucucaa gaacuauauu gacaaacaac uucuacccau acucaacaaa caaagcugca      600

gcauauccaa caucgaaacc gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

uaacccgcga guucagcguu aacgccggag ucacuacccc ugucuccacc uacaugcuca      720

ccaacuccga acuccuauca cuaaucaacg acaugcccau aaccaacgac cagaagaaac      780

ucauguccaa caacguccaa auuguccgac aacaaagcua cuccauaaug ugcauaauaa      840

aagaggaagu ccucgccuac gucguacaac ugccccuuua uggcguaauc gacacacccu      900

gcuggaaacu ccacacguca ccccucugca ccaccaacac aaaagaaggc ucgaacaucu      960

gccuaacacg gacugaccgc ggcugguacu gcgacaacgc cggcuccguc agcuucuucc     1020

cacaagccga aaccugcaaa guacaaucca accgaguauu cugcgacacc augaacucca     1080

gaacccuccc cucagagguc aaccugugca acguagacau cuucaacccc aaauacgacu     1140

gcaaaauaau gaccucaaaa acagacgucu ccucuuccgu aaucaccagc cucggagcca     1200

ucgucagcug cuacggcaaa accaaaugca ccgccucaaa caaaugccgc ggcaucauca     1260

aaacauucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacaca guaagcguag     1320

gcaacacacu guacuacguc aacaaacaag agggaaaauc acucuacguc aaaggagaac     1380

ccauaaucaa cuucuacgac ccccucguuu uccccagcga cgaguucgac gccagcauau     1440

cccaagucaa cgagaaaauu aaccaauccc uagcauucau ccgaaaaucu gacgaacugc     1500

uccacaacgu caacgcggga aaaucaacaa ccaacauaau gauaaccaca aucauaauag     1560

ucaucaucgu aauccuccuc agccuaaucg cugucggccu ccuccucuac ugcaaagccc     1620

guuccacccc agucacacuu uccaaggacc aacuaagcgg aauaaacaac aucgcguucu     1680

caaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  5487
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5487
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5488
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5488
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5489
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5489
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5490
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5490
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1740

aaggaccagc ucuccgggau aaacaauauc gcuuucucaa acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5491
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5491
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5492
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5492
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1740

aaggaccagc ucucuggaau uaacaauauc gcguucucca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5493
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5493
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uuaaagccaa cgcaauaaca acaauucuca cugcugucac cuucugcuuc      240

gccucaggcc aaaacauaac ggaagaauuu uaccaaucaa caugcucugc aguauccaaa      300

ggcuaccuau cugcucuaag aacagguugg uauacaucag uaauaaccau agaacuauca      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uuaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguuaccgaa cuacaacuac uuaugcaauc cacucccgcc      480

acuggaucag gaucagcaau agcaucagga gucgcaguau guaaagucuu acaccucgaa      540

ggcgaaguca auaaaaucaa auccgcauua cuauccacaa acaaagcagu cguaucccua      600

agcggaugcg gaguaucagu acuaacauuu aaaguacuag accuaaaaaa uuacaucgau      660

aaacaacuau uaccuauauu aaacaaacaa uccugcucca uuucaaauau cgaaaccgua      720

auagaauuuc aacaaaaaaa caacagauua cuagaaauaa caagagaauu uuccguaaau      780

gcuggcguaa caacaccagu auccacauac augcucacaa acuccgaacu acuaucacua      840

auaaaugaca ugcccauaac aaacgaucaa aaaaaacuaa ugucaaauaa uguacaaaua      900

guaagacaac aaagcuacuc caucaugugu auaauaaaag aagaaguacu agcauacgua      960

guucaacuac cacuuuacgg cguaaucgac accccuugcu ggaaacuaca caccuccccu     1020

cuaugcacca caaacacaaa agaagguucc aacauaugcc uuaccagaac agacagaggc     1080

ugguauugcg acaacgcagg aucaguuuca uuuuuuccac aagcugaaac augcaaagua     1140

caaucaaaca gagucuucug cgacacaaug aacucaagaa cucuacccuc agaaguaaac     1200

cuauguaacg uagacauuuu caaccccaaa uacgacugca aaauuaugac aucaaaaaca     1260

gacguuucau caucaguuau caccucauua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucaaauaa augcagagga auaauaaaaa cuuucuccaa cggaugcgac     1380

uacguuucaa acaaaggugu agacacugua ucaguaggaa acacacuaua uuacguaaau     1440

aaacaagaag gaaaaucacu uuaugucaaa ggagaaccaa uaaucaauuu cuacgaccca     1500

uuaguauucc caucagacga auuugaugcu ucaauaucac aaguaaacga aaaaauaaau     1560

caaucacucg cauuuauacg aaaaucagac gaacuacuac acaauguaaa cgcaggcaaa     1620

ucaacaacaa acauaaugau aacaacaaua aucauuguaa uaauaguaau acuucuaucu     1680

cuaauagcag uaggauuacu ccucuacugc aaagcaagau caaccccugu aacacuauca     1740

aaagaccaac uuucagguau aaauaauaua gcuuuuucca auuaaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5494
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5494
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccuaaucc ucaaagccaa cgcgaucacu acaauccuca cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaggaguuc uaccaaucaa ccugcuccgc cguaucaaaa      300

ggauaccuaa gcgcccuacg gaccggcugg uacacaucug ucaucaccau cgaacuauca      360

aacaucaaag aaaacaaaug caacggaacc gacgcaaaag ucaaacugau uaaacaagaa      420

cuagacaaau acaaaaacgc agucaccgaa cugcaauuac ucaugcaaag cacaccggcc      480

accggcucag gcagcgccau cgccuccggc gucgccgucu gcaaaguucu ccaccucgag      540

ggcgaaguca acaaaauaaa aucugcccuc cucuccacca acaaagccgu cgucucccuc      600

agcggcugcg gagucuccgu ccucaccuuc aaaguucucg aucucaagaa cuauauugac      660

aaacaacuuc uacccauacu caacaaacaa agcugcagca uauccaacau cgaaaccguc      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauaa cccgcgaguu cagcguuaac      780

gccggaguca cuaccccugu cuccaccuac augcucacca acuccgaacu ccuaucacua      840

aucaacgaca ugcccauaac caacgaccag aagaaacuca uguccaacaa cguccaaauu      900

guccgacaac aaagcuacuc cauaaugugc auaauaaaag aggaaguccu cgccuacguc      960

guacaacugc cccuuuaugg cguaaucgac acacccugcu ggaaacucca cacgucaccc     1020

cucugcacca ccaacacaaa agaaggcucg aacaucugcc uaacacggac ugaccgcggc     1080

ugguacugcg acaacgccgg cuccgucagc uucuucccac aagccgaaac cugcaaagua     1140

caauccaacc gaguauucug cgacaccaug aacuccagaa cccuccccuc agaggucaac     1200

cugugcaacg uagacaucuu caaccccaaa uacgacugca aaauaaugac cucaaaaaca     1260

gacgucuccu cuuccguaau caccagccuc ggagccaucg ucagcugcua cggcaaaacc     1320

aaaugcaccg ccucaaacaa augccgcggc aucaucaaaa cauucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacacagua agcguaggca acacacugua cuacgucaac     1440

aaacaagagg gaaaaucacu cuacgucaaa ggagaaccca uaaucaacuu cuacgacccc     1500

cucguuuucc ccagcgacga guucgacgcc agcauauccc aagucaacga gaaaauuaac     1560

caaucccuag cauucauccg aaaaucugac gaacugcucc acaacgucaa cgcgggaaaa     1620

ucaacaacca acauaaugau aaccacaauc auaauaguca ucaucguaau ccuccucagc     1680

cuaaucgcug ucggccuccu ccucuacugc aaagcccguu ccaccccagu cacacuuucc     1740

aaggaccaac uaagcggaau aaacaacauc gcguucucaa acuaaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  5495
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5495
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      660

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      720

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      780

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      900

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      960

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1020

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1080

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1260

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1380

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1440

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1560

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1620

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1680

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5496
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5496
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      480

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      540

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      600

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      660

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      720

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc      960

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg     1020

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1140

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1200

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1260

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1380

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1440

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1500

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1560

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1620

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguccacccc ggugacccug     1680

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5497
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5497
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      600

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      660

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      720

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      840

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      900

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      960

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1020

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1260

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1320

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1380

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1440

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1500

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1560

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1620

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1680

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5498
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5498
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      480

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      540

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      600

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      660

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      720

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      780

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      840

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau      900

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc      960

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu     1020

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1080

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1140

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1200

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1260

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1320

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1380

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1440

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1500

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1560

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1620

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcucuacacc ggugacccug     1680

agcaaggacc agcucuccgg gauaaacaau aucgcuuucu caaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5499
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5499
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      660

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      720

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      780

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      960

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1020

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1080

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1140

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1200

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1260

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1380

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1440

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1560

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1620

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1680

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5500
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5500
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      480

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      540

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      600

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      660

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      720

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      780

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      840

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau      900

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu      960

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc     1020

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1080

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1140

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1200

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1260

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1320

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1380

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1440

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1500

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1560

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1620

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gauccacacc ugugacccuu     1680

agcaaggacc agcucucugg aauuaacaau aucgcguucu ccaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5501
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5501
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc ucacugcugu caccuucugc      180

uucgccucag gccaaaacau aacggaagaa uuuuaccaau caacaugcuc ugcaguaucc      240

aaaggcuacc uaucugcucu aagaacaggu ugguauacau caguaauaac cauagaacua      300

ucaaacauaa aagaaaauaa augcaacgga acagacgcaa aaguuaaacu cauaaaacaa      360

gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac uacuuaugca auccacuccc      420

gccacuggau caggaucagc aauagcauca ggagucgcag uauguaaagu cuuacaccuc      480

gaaggcgaag ucaauaaaau caaauccgca uuacuaucca caaacaaagc agucguaucc      540

cuaagcggau gcggaguauc aguacuaaca uuuaaaguac uagaccuaaa aaauuacauc      600

gauaaacaac uauuaccuau auuaaacaaa caauccugcu ccauuucaaa uaucgaaacc      660

guaauagaau uucaacaaaa aaacaacaga uuacuagaaa uaacaagaga auuuuccgua      720

aaugcuggcg uaacaacacc aguauccaca uacaugcuca caaacuccga acuacuauca      780

cuaauaaaug acaugcccau aacaaacgau caaaaaaaac uaaugucaaa uaauguacaa      840

auaguaagac aacaaagcua cuccaucaug uguauaauaa aagaagaagu acuagcauac      900

guaguucaac uaccacuuua cggcguaauc gacaccccuu gcuggaaacu acacaccucc      960

ccucuaugca ccacaaacac aaaagaaggu uccaacauau gccuuaccag aacagacaga     1020

ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc cacaagcuga aacaugcaaa     1080

guacaaucaa acagagucuu cugcgacaca augaacucaa gaacucuacc cucagaagua     1140

aaccuaugua acguagacau uuucaacccc aaauacgacu gcaaaauuau gacaucaaaa     1200

acagacguuu caucaucagu uaucaccuca uuaggagcaa uaguaagcug cuacggaaaa     1260

acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa aaacuuucuc caacggaugc     1320

gacuacguuu caaacaaagg uguagacacu guaucaguag gaaacacacu auauuacgua     1380

aauaaacaag aaggaaaauc acuuuauguc aaaggagaac caauaaucaa uuucuacgac     1440

ccauuaguau ucccaucaga cgaauuugau gcuucaauau cacaaguaaa cgaaaaaaua     1500

aaucaaucac ucgcauuuau acgaaaauca gacgaacuac uacacaaugu aaacgcaggc     1560

aaaucaacaa caaacauaau gauaacaaca auaaucauug uaauaauagu aauacuucua     1620

ucucuaauag caguaggauu acuccucuac ugcaaagcaa gaucaacccc uguaacacua     1680

ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu ccaauuaagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5502
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5502
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuaa uccucaaagc caacgcgauc acuacaaucc ucacagccgu caccuucugc      180

uucgccuccg gccaaaacau caccgaggag uucuaccaau caaccugcuc cgccguauca      240

aaaggauacc uaagcgcccu acggaccggc ugguacacau cugucaucac caucgaacua      300

ucaaacauca aagaaaacaa augcaacgga accgacgcaa aagucaaacu gauuaaacaa      360

gaacuagaca aauacaaaaa cgcagucacc gaacugcaau uacucaugca aagcacaccg      420

gccaccggcu caggcagcgc caucgccucc ggcgucgccg ucugcaaagu ucuccaccuc      480

gagggcgaag ucaacaaaau aaaaucugcc cuccucucca ccaacaaagc cgucgucucc      540

cucagcggcu gcggagucuc cguccucacc uucaaaguuc ucgaucucaa gaacuauauu      600

gacaaacaac uucuacccau acucaacaaa caaagcugca gcauauccaa caucgaaacc      660

gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa uaacccgcga guucagcguu      720

aacgccggag ucacuacccc ugucuccacc uacaugcuca ccaacuccga acuccuauca      780

cuaaucaacg acaugcccau aaccaacgac cagaagaaac ucauguccaa caacguccaa      840

auuguccgac aacaaagcua cuccauaaug ugcauaauaa aagaggaagu ccucgccuac      900

gucguacaac ugccccuuua uggcguaauc gacacacccu gcuggaaacu ccacacguca      960

ccccucugca ccaccaacac aaaagaaggc ucgaacaucu gccuaacacg gacugaccgc     1020

ggcugguacu gcgacaacgc cggcuccguc agcuucuucc cacaagccga aaccugcaaa     1080

guacaaucca accgaguauu cugcgacacc augaacucca gaacccuccc cucagagguc     1140

aaccugugca acguagacau cuucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1200

acagacgucu ccucuuccgu aaucaccagc cucggagcca ucgucagcug cuacggcaaa     1260

accaaaugca ccgccucaaa caaaugccgc ggcaucauca aaacauucuc aaacggcugc     1320

gacuacgucu ccaacaaagg cgucgacaca guaagcguag gcaacacacu guacuacguc     1380

aacaaacaag agggaaaauc acucuacguc aaaggagaac ccauaaucaa cuucuacgac     1440

ccccucguuu uccccagcga cgaguucgac gccagcauau cccaagucaa cgagaaaauu     1500

aaccaauccc uagcauucau ccgaaaaucu gacgaacugc uccacaacgu caacgcggga     1560

aaaucaacaa ccaacauaau gauaaccaca aucauaauag ucaucaucgu aauccuccuc     1620

agccuaaucg cugucggccu ccuccucuac ugcaaagccc guuccacccc agucacacuu     1680

uccaaggacc aacuaagcgg aauaaacaac aucgcguucu caaacuaagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  5503
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5503
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5504
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5504
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccgguccacc ccggugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5505
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5505
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5506
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5506
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcucuaca ccggugaccc ugagcaagga ccagcucucc     1680

gggauaaaca auaucgcuuu cucaaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5507
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5507
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5508
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5508
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagauccaca ccugugaccc uuagcaagga ccagcucucu     1680

ggaauuaaca auaucgcguu cuccaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5509
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5509
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuuaaa      120

gccaacgcaa uaacaacaau ucucacugcu gucaccuucu gcuucgccuc aggccaaaac      180

auaacggaag aauuuuacca aucaacaugc ucugcaguau ccaaaggcua ccuaucugcu      240

cuaagaacag guugguauac aucaguaaua accauagaac uaucaaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguuaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguua ccgaacuaca acuacuuaug caauccacuc ccgccacugg aucaggauca      420

gcaauagcau caggagucgc aguauguaaa gucuuacacc ucgaaggcga agucaauaaa      480

aucaaauccg cauuacuauc cacaaacaaa gcagucguau cccuaagcgg augcggagua      540

ucaguacuaa cauuuaaagu acuagaccua aaaaauuaca ucgauaaaca acuauuaccu      600

auauuaaaca aacaauccug cuccauuuca aauaucgaaa ccguaauaga auuucaacaa      660

aaaaacaaca gauuacuaga aauaacaaga gaauuuuccg uaaaugcugg cguaacaaca      720

ccaguaucca cauacaugcu cacaaacucc gaacuacuau cacuaauaaa ugacaugccc      780

auaacaaacg aucaaaaaaa acuaauguca aauaauguac aaauaguaag acaacaaagc      840

uacuccauca uguguauaau aaaagaagaa guacuagcau acguaguuca acuaccacuu      900

uacggcguaa ucgacacccc uugcuggaaa cuacacaccu ccccucuaug caccacaaac      960

acaaaagaag guuccaacau augccuuacc agaacagaca gaggcuggua uugcgacaac     1020

gcaggaucag uuucauuuuu uccacaagcu gaaacaugca aaguacaauc aaacagaguc     1080

uucugcgaca caaugaacuc aagaacucua cccucagaag uaaaccuaug uaacguagac     1140

auuuucaacc ccaaauacga cugcaaaauu augacaucaa aaacagacgu uucaucauca     1200

guuaucaccu cauuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccuca     1260

aauaaaugca gaggaauaau aaaaacuuuc uccaacggau gcgacuacgu uucaaacaaa     1320

gguguagaca cuguaucagu aggaaacaca cuauauuacg uaaauaaaca agaaggaaaa     1380

ucacuuuaug ucaaaggaga accaauaauc aauuucuacg acccauuagu auucccauca     1440

gacgaauuug augcuucaau aucacaagua aacgaaaaaa uaaaucaauc acucgcauuu     1500

auacgaaaau cagacgaacu acuacacaau guaaacgcag gcaaaucaac aacaaacaua     1560

augauaacaa caauaaucau uguaauaaua guaauacuuc uaucucuaau agcaguagga     1620

uuacuccucu acugcaaagc aagaucaacc ccuguaacac uaucaaaaga ccaacuuuca     1680

gguauaaaua auauagcuuu uuccaauuaa ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5510
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5510
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu aauccucaaa      120

gccaacgcga ucacuacaau ccucacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgagg aguucuacca aucaaccugc uccgccguau caaaaggaua ccuaagcgcc      240

cuacggaccg gcugguacac aucugucauc accaucgaac uaucaaacau caaagaaaac      300

aaaugcaacg gaaccgacgc aaaagucaaa cugauuaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaacugca auuacucaug caaagcacac cggccaccgg cucaggcagc      420

gccaucgccu ccggcgucgc cgucugcaaa guucuccacc ucgagggcga agucaacaaa      480

auaaaaucug cccuccucuc caccaacaaa gccgucgucu cccucagcgg cugcggaguc      540

uccguccuca ccuucaaagu ucucgaucuc aagaacuaua uugacaaaca acuucuaccc      600

auacucaaca aacaaagcug cagcauaucc aacaucgaaa ccgucaucga guuccaacaa      660

aagaacaacc gccuccucga aauaacccgc gaguucagcg uuaacgccgg agucacuacc      720

ccugucucca ccuacaugcu caccaacucc gaacuccuau cacuaaucaa cgacaugccc      780

auaaccaacg accagaagaa acucaugucc aacaacgucc aaauuguccg acaacaaagc      840

uacuccauaa ugugcauaau aaaagaggaa guccucgccu acgucguaca acugccccuu      900

uauggcguaa ucgacacacc cugcuggaaa cuccacacgu caccccucug caccaccaac      960

acaaaagaag gcucgaacau cugccuaaca cggacugacc gcggcuggua cugcgacaac     1020

gccggcuccg ucagcuucuu cccacaagcc gaaaccugca aaguacaauc caaccgagua     1080

uucugcgaca ccaugaacuc cagaacccuc cccucagagg ucaaccugug caacguagac     1140

aucuucaacc ccaaauacga cugcaaaaua augaccucaa aaacagacgu cuccucuucc     1200

guaaucacca gccucggagc caucgucagc ugcuacggca aaaccaaaug caccgccuca     1260

aacaaaugcc gcggcaucau caaaacauuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca caguaagcgu aggcaacaca cuguacuacg ucaacaaaca agagggaaaa     1380

ucacucuacg ucaaaggaga acccauaauc aacuucuacg acccccucgu uuuccccagc     1440

gacgaguucg acgccagcau aucccaaguc aacgagaaaa uuaaccaauc ccuagcauuc     1500

auccgaaaau cugacgaacu gcuccacaac gucaacgcgg gaaaaucaac aaccaacaua     1560

augauaacca caaucauaau agucaucauc guaauccucc ucagccuaau cgcugucggc     1620

cuccuccucu acugcaaagc ccguuccacc ccagucacac uuuccaagga ccaacuaagc     1680

ggaauaaaca acaucgcguu cucaaacuaa ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  5511
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5511
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5512
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5512
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccgguccacc     1620

ccggugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5513
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5513
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5514
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5514
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcucuaca     1620

ccggugaccc ugagcaagga ccagcucucc gggauaaaca auaucgcuuu cucaaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5515
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5515
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5516
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5516
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagauccaca     1620

ccugugaccc uuagcaagga ccagcucucu ggaauuaaca auaucgcguu cuccaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5517
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5517
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuuaaa gccaacgcaa uaacaacaau ucucacugcu      120

gucaccuucu gcuucgccuc aggccaaaac auaacggaag aauuuuacca aucaacaugc      180

ucugcaguau ccaaaggcua ccuaucugcu cuaagaacag guugguauac aucaguaaua      240

accauagaac uaucaaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguuaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguua ccgaacuaca acuacuuaug      360

caauccacuc ccgccacugg aucaggauca gcaauagcau caggagucgc aguauguaaa      420

gucuuacacc ucgaaggcga agucaauaaa aucaaauccg cauuacuauc cacaaacaaa      480

gcagucguau cccuaagcgg augcggagua ucaguacuaa cauuuaaagu acuagaccua      540

aaaaauuaca ucgauaaaca acuauuaccu auauuaaaca aacaauccug cuccauuuca      600

aauaucgaaa ccguaauaga auuucaacaa aaaaacaaca gauuacuaga aauaacaaga      660

gaauuuuccg uaaaugcugg cguaacaaca ccaguaucca cauacaugcu cacaaacucc      720

gaacuacuau cacuaauaaa ugacaugccc auaacaaacg aucaaaaaaa acuaauguca      780

aauaauguac aaauaguaag acaacaaagc uacuccauca uguguauaau aaaagaagaa      840

guacuagcau acguaguuca acuaccacuu uacggcguaa ucgacacccc uugcuggaaa      900

cuacacaccu ccccucuaug caccacaaac acaaaagaag guuccaacau augccuuacc      960

agaacagaca gaggcuggua uugcgacaac gcaggaucag uuucauuuuu uccacaagcu     1020

gaaacaugca aaguacaauc aaacagaguc uucugcgaca caaugaacuc aagaacucua     1080

cccucagaag uaaaccuaug uaacguagac auuuucaacc ccaaauacga cugcaaaauu     1140

augacaucaa aaacagacgu uucaucauca guuaucaccu cauuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccuca aauaaaugca gaggaauaau aaaaacuuuc     1260

uccaacggau gcgacuacgu uucaaacaaa gguguagaca cuguaucagu aggaaacaca     1320

cuauauuacg uaaauaaaca agaaggaaaa ucacuuuaug ucaaaggaga accaauaauc     1380

aauuucuacg acccauuagu auucccauca gacgaauuug augcuucaau aucacaagua     1440

aacgaaaaaa uaaaucaauc acucgcauuu auacgaaaau cagacgaacu acuacacaau     1500

guaaacgcag gcaaaucaac aacaaacaua augauaacaa caauaaucau uguaauaaua     1560

guaauacuuc uaucucuaau agcaguagga uuacuccucu acugcaaagc aagaucaacc     1620

ccuguaacac uaucaaaaga ccaacuuuca gguauaaaua auauagcuuu uuccaauuaa     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5518
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5518
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu aauccucaaa gccaacgcga ucacuacaau ccucacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgagg aguucuacca aucaaccugc      180

uccgccguau caaaaggaua ccuaagcgcc cuacggaccg gcugguacac aucugucauc      240

accaucgaac uaucaaacau caaagaaaac aaaugcaacg gaaccgacgc aaaagucaaa      300

cugauuaaac aagaacuaga caaauacaaa aacgcaguca ccgaacugca auuacucaug      360

caaagcacac cggccaccgg cucaggcagc gccaucgccu ccggcgucgc cgucugcaaa      420

guucuccacc ucgagggcga agucaacaaa auaaaaucug cccuccucuc caccaacaaa      480

gccgucgucu cccucagcgg cugcggaguc uccguccuca ccuucaaagu ucucgaucuc      540

aagaacuaua uugacaaaca acuucuaccc auacucaaca aacaaagcug cagcauaucc      600

aacaucgaaa ccgucaucga guuccaacaa aagaacaacc gccuccucga aauaacccgc      660

gaguucagcg uuaacgccgg agucacuacc ccugucucca ccuacaugcu caccaacucc      720

gaacuccuau cacuaaucaa cgacaugccc auaaccaacg accagaagaa acucaugucc      780

aacaacgucc aaauuguccg acaacaaagc uacuccauaa ugugcauaau aaaagaggaa      840

guccucgccu acgucguaca acugccccuu uauggcguaa ucgacacacc cugcuggaaa      900

cuccacacgu caccccucug caccaccaac acaaaagaag gcucgaacau cugccuaaca      960

cggacugacc gcggcuggua cugcgacaac gccggcuccg ucagcuucuu cccacaagcc     1020

gaaaccugca aaguacaauc caaccgagua uucugcgaca ccaugaacuc cagaacccuc     1080

cccucagagg ucaaccugug caacguagac aucuucaacc ccaaauacga cugcaaaaua     1140

augaccucaa aaacagacgu cuccucuucc guaaucacca gccucggagc caucgucagc     1200

ugcuacggca aaaccaaaug caccgccuca aacaaaugcc gcggcaucau caaaacauuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca caguaagcgu aggcaacaca     1320

cuguacuacg ucaacaaaca agagggaaaa ucacucuacg ucaaaggaga acccauaauc     1380

aacuucuacg acccccucgu uuuccccagc gacgaguucg acgccagcau aucccaaguc     1440

aacgagaaaa uuaaccaauc ccuagcauuc auccgaaaau cugacgaacu gcuccacaac     1500

gucaacgcgg gaaaaucaac aaccaacaua augauaacca caaucauaau agucaucauc     1560

guaauccucc ucagccuaau cgcugucggc cuccuccucu acugcaaagc ccguuccacc     1620

ccagucacac uuuccaagga ccaacuaagc ggaauaaaca acaucgcguu cucaaacuaa     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5519
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5519
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5520
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5520
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccgguc caccccggug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5521
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5521
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5522
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5522
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcuc uacaccggug     1680

acccugagca aggaccagcu cuccgggaua aacaauaucg cuuucucaaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5523
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5523
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5524
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5524
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagauc cacaccugug     1680

acccuuagca aggaccagcu cucuggaauu aacaauaucg cguucuccaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5525
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5525
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu uaaagccaac gcaauaacaa caauucucac ugcugucacc      180

uucugcuucg ccucaggcca aaacauaacg gaagaauuuu accaaucaac augcucugca      240

guauccaaag gcuaccuauc ugcucuaaga acagguuggu auacaucagu aauaaccaua      300

gaacuaucaa acauaaaaga aaauaaaugc aacggaacag acgcaaaagu uaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guuaccgaac uacaacuacu uaugcaaucc      420

acucccgcca cuggaucagg aucagcaaua gcaucaggag ucgcaguaug uaaagucuua      480

caccucgaag gcgaagucaa uaaaaucaaa uccgcauuac uauccacaaa caaagcaguc      540

guaucccuaa gcggaugcgg aguaucagua cuaacauuua aaguacuaga ccuaaaaaau      600

uacaucgaua aacaacuauu accuauauua aacaaacaau ccugcuccau uucaaauauc      660

gaaaccguaa uagaauuuca acaaaaaaac aacagauuac uagaaauaac aagagaauuu      720

uccguaaaug cuggcguaac aacaccagua uccacauaca ugcucacaaa cuccgaacua      780

cuaucacuaa uaaaugacau gcccauaaca aacgaucaaa aaaaacuaau gucaaauaau      840

guacaaauag uaagacaaca aagcuacucc aucaugugua uaauaaaaga agaaguacua      900

gcauacguag uucaacuacc acuuuacggc guaaucgaca ccccuugcug gaaacuacac      960

accuccccuc uaugcaccac aaacacaaaa gaagguucca acauaugccu uaccagaaca     1020

gacagaggcu gguauugcga caacgcagga ucaguuucau uuuuuccaca agcugaaaca     1080

ugcaaaguac aaucaaacag agucuucugc gacacaauga acucaagaac ucuacccuca     1140

gaaguaaacc uauguaacgu agacauuuuc aaccccaaau acgacugcaa aauuaugaca     1200

ucaaaaacag acguuucauc aucaguuauc accucauuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucaaauaaa ugcagaggaa uaauaaaaac uuucuccaac     1320

ggaugcgacu acguuucaaa caaaggugua gacacuguau caguaggaaa cacacuauau     1380

uacguaaaua aacaagaagg aaaaucacuu uaugucaaag gagaaccaau aaucaauuuc     1440

uacgacccau uaguauuccc aucagacgaa uuugaugcuu caauaucaca aguaaacgaa     1500

aaaauaaauc aaucacucgc auuuauacga aaaucagacg aacuacuaca caauguaaac     1560

gcaggcaaau caacaacaaa cauaaugaua acaacaauaa ucauuguaau aauaguaaua     1620

cuucuaucuc uaauagcagu aggauuacuc cucuacugca aagcaagauc aaccccugua     1680

acacuaucaa aagaccaacu uucagguaua aauaauauag cuuuuuccaa uuaaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5526
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5526
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccuaauccu caaagccaac gcgaucacua caauccucac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaggaguucu accaaucaac cugcuccgcc      240

guaucaaaag gauaccuaag cgcccuacgg accggcuggu acacaucugu caucaccauc      300

gaacuaucaa acaucaaaga aaacaaaugc aacggaaccg acgcaaaagu caaacugauu      360

aaacaagaac uagacaaaua caaaaacgca gucaccgaac ugcaauuacu caugcaaagc      420

acaccggcca ccggcucagg cagcgccauc gccuccggcg ucgccgucug caaaguucuc      480

caccucgagg gcgaagucaa caaaauaaaa ucugcccucc ucuccaccaa caaagccguc      540

gucucccuca gcggcugcgg agucuccguc cucaccuuca aaguucucga ucucaagaac      600

uauauugaca aacaacuucu acccauacuc aacaaacaaa gcugcagcau auccaacauc      660

gaaaccguca ucgaguucca acaaaagaac aaccgccucc ucgaaauaac ccgcgaguuc      720

agcguuaacg ccggagucac uaccccuguc uccaccuaca ugcucaccaa cuccgaacuc      780

cuaucacuaa ucaacgacau gcccauaacc aacgaccaga agaaacucau guccaacaac      840

guccaaauug uccgacaaca aagcuacucc auaaugugca uaauaaaaga ggaaguccuc      900

gccuacgucg uacaacugcc ccuuuauggc guaaucgaca cacccugcug gaaacuccac      960

acgucacccc ucugcaccac caacacaaaa gaaggcucga acaucugccu aacacggacu     1020

gaccgcggcu gguacugcga caacgccggc uccgucagcu ucuucccaca agccgaaacc     1080

ugcaaaguac aauccaaccg aguauucugc gacaccauga acuccagaac ccuccccuca     1140

gaggucaacc ugugcaacgu agacaucuuc aaccccaaau acgacugcaa aauaaugacc     1200

ucaaaaacag acgucuccuc uuccguaauc accagccucg gagccaucgu cagcugcuac     1260

ggcaaaacca aaugcaccgc cucaaacaaa ugccgcggca ucaucaaaac auucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacacaguaa gcguaggcaa cacacuguac     1380

uacgucaaca aacaagaggg aaaaucacuc uacgucaaag gagaacccau aaucaacuuc     1440

uacgaccccc ucguuuuccc cagcgacgag uucgacgcca gcauauccca agucaacgag     1500

aaaauuaacc aaucccuagc auucauccga aaaucugacg aacugcucca caacgucaac     1560

gcgggaaaau caacaaccaa cauaaugaua accacaauca uaauagucau caucguaauc     1620

cuccucagcc uaaucgcugu cggccuccuc cucuacugca aagcccguuc caccccaguc     1680

acacuuucca aggaccaacu aagcggaaua aacaacaucg cguucucaaa cuaaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5527
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5527
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5528
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5528
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccgguccac cccggugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5529
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5529
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5530
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5530
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcucuac accggugacc cugagcaagg accagcucuc cgggauaaac     1680

aauaucgcuu ucucaaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5531
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5531
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5532
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5532
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagauccac accugugacc cuuagcaagg accagcucuc uggaauuaac     1680

aauaucgcgu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5533
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5533
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuuaa agccaacgca      120

auaacaacaa uucucacugc ugucaccuuc ugcuucgccu caggccaaaa cauaacggaa      180

gaauuuuacc aaucaacaug cucugcagua uccaaaggcu accuaucugc ucuaagaaca      240

gguugguaua caucaguaau aaccauagaa cuaucaaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguuaa acucauaaaa caagaacuag acaaauauaa aaacgcaguu      360

accgaacuac aacuacuuau gcaauccacu cccgccacug gaucaggauc agcaauagca      420

ucaggagucg caguauguaa agucuuacac cucgaaggcg aagucaauaa aaucaaaucc      480

gcauuacuau ccacaaacaa agcagucgua ucccuaagcg gaugcggagu aucaguacua      540

acauuuaaag uacuagaccu aaaaaauuac aucgauaaac aacuauuacc uauauuaaac      600

aaacaauccu gcuccauuuc aaauaucgaa accguaauag aauuucaaca aaaaaacaac      660

agauuacuag aaauaacaag agaauuuucc guaaaugcug gcguaacaac accaguaucc      720

acauacaugc ucacaaacuc cgaacuacua ucacuaauaa augacaugcc cauaacaaac      780

gaucaaaaaa aacuaauguc aaauaaugua caaauaguaa gacaacaaag cuacuccauc      840

auguguauaa uaaaagaaga aguacuagca uacguaguuc aacuaccacu uuacggcgua      900

aucgacaccc cuugcuggaa acuacacacc uccccucuau gcaccacaaa cacaaaagaa      960

gguuccaaca uaugccuuac cagaacagac agaggcuggu auugcgacaa cgcaggauca     1020

guuucauuuu uuccacaagc ugaaacaugc aaaguacaau caaacagagu cuucugcgac     1080

acaaugaacu caagaacucu acccucagaa guaaaccuau guaacguaga cauuuucaac     1140

cccaaauacg acugcaaaau uaugacauca aaaacagacg uuucaucauc aguuaucacc     1200

ucauuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc aaauaaaugc     1260

agaggaauaa uaaaaacuuu cuccaacgga ugcgacuacg uuucaaacaa agguguagac     1320

acuguaucag uaggaaacac acuauauuac guaaauaaac aagaaggaaa aucacuuuau     1380

gucaaaggag aaccaauaau caauuucuac gacccauuag uauucccauc agacgaauuu     1440

gaugcuucaa uaucacaagu aaacgaaaaa auaaaucaau cacucgcauu uauacgaaaa     1500

ucagacgaac uacuacacaa uguaaacgca ggcaaaucaa caacaaacau aaugauaaca     1560

acaauaauca uuguaauaau aguaauacuu cuaucucuaa uagcaguagg auuacuccuc     1620

uacugcaaag caagaucaac cccuguaaca cuaucaaaag accaacuuuc agguauaaau     1680

aauauagcuu uuuccaauua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5534
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5534
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc uaauccucaa agccaacgcg      120

aucacuacaa uccucacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgag      180

gaguucuacc aaucaaccug cuccgccgua ucaaaaggau accuaagcgc ccuacggacc      240

ggcugguaca caucugucau caccaucgaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggaaccgacg caaaagucaa acugauuaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaacugc aauuacucau gcaaagcaca ccggccaccg gcucaggcag cgccaucgcc      420

uccggcgucg ccgucugcaa aguucuccac cucgagggcg aagucaacaa aauaaaaucu      480

gcccuccucu ccaccaacaa agccgucguc ucccucagcg gcugcggagu cuccguccuc      540

accuucaaag uucucgaucu caagaacuau auugacaaac aacuucuacc cauacucaac      600

aaacaaagcu gcagcauauc caacaucgaa accgucaucg aguuccaaca aaagaacaac      660

cgccuccucg aaauaacccg cgaguucagc guuaacgccg gagucacuac cccugucucc      720

accuacaugc ucaccaacuc cgaacuccua ucacuaauca acgacaugcc cauaaccaac      780

gaccagaaga aacucauguc caacaacguc caaauugucc gacaacaaag cuacuccaua      840

augugcauaa uaaaagagga aguccucgcc uacgucguac aacugccccu uuauggcgua      900

aucgacacac ccugcuggaa acuccacacg ucaccccucu gcaccaccaa cacaaaagaa      960

ggcucgaaca ucugccuaac acggacugac cgcggcuggu acugcgacaa cgccggcucc     1020

gucagcuucu ucccacaagc cgaaaccugc aaaguacaau ccaaccgagu auucugcgac     1080

accaugaacu ccagaacccu ccccucagag gucaaccugu gcaacguaga caucuucaac     1140

cccaaauacg acugcaaaau aaugaccuca aaaacagacg ucuccucuuc cguaaucacc     1200

agccucggag ccaucgucag cugcuacggc aaaaccaaau gcaccgccuc aaacaaaugc     1260

cgcggcauca ucaaaacauu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

acaguaagcg uaggcaacac acuguacuac gucaacaaac aagagggaaa aucacucuac     1380

gucaaaggag aacccauaau caacuucuac gacccccucg uuuuccccag cgacgaguuc     1440

gacgccagca uaucccaagu caacgagaaa auuaaccaau cccuagcauu cauccgaaaa     1500

ucugacgaac ugcuccacaa cgucaacgcg ggaaaaucaa caaccaacau aaugauaacc     1560

acaaucauaa uagucaucau cguaauccuc cucagccuaa ucgcugucgg ccuccuccuc     1620

uacugcaaag cccguuccac cccagucaca cuuuccaagg accaacuaag cggaauaaac     1680

aacaucgcgu ucucaaacua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5535
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5535
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5536
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5536
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccgguccac cccggugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5537
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5537
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5538
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5538
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcucuac accggugacc cugagcaagg accagcucuc cgggauaaac     1680

aauaucgcuu ucucaaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5539
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5539
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5540
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5540
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagauccac accugugacc cuuagcaagg accagcucuc uggaauuaac     1680

aauaucgcgu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5541
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5541
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuuaa agccaacgca      120

auaacaacaa uucucacugc ugucaccuuc ugcuucgccu caggccaaaa cauaacggaa      180

gaauuuuacc aaucaacaug cucugcagua uccaaaggcu accuaucugc ucuaagaaca      240

gguugguaua caucaguaau aaccauagaa cuaucaaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguuaa acucauaaaa caagaacuag acaaauauaa aaacgcaguu      360

accgaacuac aacuacuuau gcaauccacu cccgccacug gaucaggauc agcaauagca      420

ucaggagucg caguauguaa agucuuacac cucgaaggcg aagucaauaa aaucaaaucc      480

gcauuacuau ccacaaacaa agcagucgua ucccuaagcg gaugcggagu aucaguacua      540

acauuuaaag uacuagaccu aaaaaauuac aucgauaaac aacuauuacc uauauuaaac      600

aaacaauccu gcuccauuuc aaauaucgaa accguaauag aauuucaaca aaaaaacaac      660

agauuacuag aaauaacaag agaauuuucc guaaaugcug gcguaacaac accaguaucc      720

acauacaugc ucacaaacuc cgaacuacua ucacuaauaa augacaugcc cauaacaaac      780

gaucaaaaaa aacuaauguc aaauaaugua caaauaguaa gacaacaaag cuacuccauc      840

auguguauaa uaaaagaaga aguacuagca uacguaguuc aacuaccacu uuacggcgua      900

aucgacaccc cuugcuggaa acuacacacc uccccucuau gcaccacaaa cacaaaagaa      960

gguuccaaca uaugccuuac cagaacagac agaggcuggu auugcgacaa cgcaggauca     1020

guuucauuuu uuccacaagc ugaaacaugc aaaguacaau caaacagagu cuucugcgac     1080

acaaugaacu caagaacucu acccucagaa guaaaccuau guaacguaga cauuuucaac     1140

cccaaauacg acugcaaaau uaugacauca aaaacagacg uuucaucauc aguuaucacc     1200

ucauuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc aaauaaaugc     1260

agaggaauaa uaaaaacuuu cuccaacgga ugcgacuacg uuucaaacaa agguguagac     1320

acuguaucag uaggaaacac acuauauuac guaaauaaac aagaaggaaa aucacuuuau     1380

gucaaaggag aaccaauaau caauuucuac gacccauuag uauucccauc agacgaauuu     1440

gaugcuucaa uaucacaagu aaacgaaaaa auaaaucaau cacucgcauu uauacgaaaa     1500

ucagacgaac uacuacacaa uguaaacgca ggcaaaucaa caacaaacau aaugauaaca     1560

acaauaauca uuguaauaau aguaauacuu cuaucucuaa uagcaguagg auuacuccuc     1620

uacugcaaag caagaucaac cccuguaaca cuaucaaaag accaacuuuc agguauaaau     1680

aauauagcuu uuuccaauua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5542
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5542
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc uaauccucaa agccaacgcg      120

aucacuacaa uccucacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgag      180

gaguucuacc aaucaaccug cuccgccgua ucaaaaggau accuaagcgc ccuacggacc      240

ggcugguaca caucugucau caccaucgaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggaaccgacg caaaagucaa acugauuaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaacugc aauuacucau gcaaagcaca ccggccaccg gcucaggcag cgccaucgcc      420

uccggcgucg ccgucugcaa aguucuccac cucgagggcg aagucaacaa aauaaaaucu      480

gcccuccucu ccaccaacaa agccgucguc ucccucagcg gcugcggagu cuccguccuc      540

accuucaaag uucucgaucu caagaacuau auugacaaac aacuucuacc cauacucaac      600

aaacaaagcu gcagcauauc caacaucgaa accgucaucg aguuccaaca aaagaacaac      660

cgccuccucg aaauaacccg cgaguucagc guuaacgccg gagucacuac cccugucucc      720

accuacaugc ucaccaacuc cgaacuccua ucacuaauca acgacaugcc cauaaccaac      780

gaccagaaga aacucauguc caacaacguc caaauugucc gacaacaaag cuacuccaua      840

augugcauaa uaaaagagga aguccucgcc uacgucguac aacugccccu uuauggcgua      900

aucgacacac ccugcuggaa acuccacacg ucaccccucu gcaccaccaa cacaaaagaa      960

ggcucgaaca ucugccuaac acggacugac cgcggcuggu acugcgacaa cgccggcucc     1020

gucagcuucu ucccacaagc cgaaaccugc aaaguacaau ccaaccgagu auucugcgac     1080

accaugaacu ccagaacccu ccccucagag gucaaccugu gcaacguaga caucuucaac     1140

cccaaauacg acugcaaaau aaugaccuca aaaacagacg ucuccucuuc cguaaucacc     1200

agccucggag ccaucgucag cugcuacggc aaaaccaaau gcaccgccuc aaacaaaugc     1260

cgcggcauca ucaaaacauu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

acaguaagcg uaggcaacac acuguacuac gucaacaaac aagagggaaa aucacucuac     1380

gucaaaggag aacccauaau caacuucuac gacccccucg uuuuccccag cgacgaguuc     1440

gacgccagca uaucccaagu caacgagaaa auuaaccaau cccuagcauu cauccgaaaa     1500

ucugacgaac ugcuccacaa cgucaacgcg ggaaaaucaa caaccaacau aaugauaacc     1560

acaaucauaa uagucaucau cguaauccuc cucagccuaa ucgcugucgg ccuccuccuc     1620

uacugcaaag cccguuccac cccagucaca cuuuccaagg accaacuaag cggaauaaac     1680

aacaucgcgu ucucaaacua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  5543
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5543
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5544
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5544
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccgguccac cccggugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5545
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5545
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5546
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5546
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcucuac accggugacc cugagcaagg accagcucuc cgggauaaac     1680

aauaucgcuu ucucaaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5547
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5547
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5548
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5548
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagauccac accugugacc cuuagcaagg accagcucuc uggaauuaac     1680

aauaucgcgu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5549
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5549
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuuaa agccaacgca      120

auaacaacaa uucucacugc ugucaccuuc ugcuucgccu caggccaaaa cauaacggaa      180

gaauuuuacc aaucaacaug cucugcagua uccaaaggcu accuaucugc ucuaagaaca      240

gguugguaua caucaguaau aaccauagaa cuaucaaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguuaa acucauaaaa caagaacuag acaaauauaa aaacgcaguu      360

accgaacuac aacuacuuau gcaauccacu cccgccacug gaucaggauc agcaauagca      420

ucaggagucg caguauguaa agucuuacac cucgaaggcg aagucaauaa aaucaaaucc      480

gcauuacuau ccacaaacaa agcagucgua ucccuaagcg gaugcggagu aucaguacua      540

acauuuaaag uacuagaccu aaaaaauuac aucgauaaac aacuauuacc uauauuaaac      600

aaacaauccu gcuccauuuc aaauaucgaa accguaauag aauuucaaca aaaaaacaac      660

agauuacuag aaauaacaag agaauuuucc guaaaugcug gcguaacaac accaguaucc      720

acauacaugc ucacaaacuc cgaacuacua ucacuaauaa augacaugcc cauaacaaac      780

gaucaaaaaa aacuaauguc aaauaaugua caaauaguaa gacaacaaag cuacuccauc      840

auguguauaa uaaaagaaga aguacuagca uacguaguuc aacuaccacu uuacggcgua      900

aucgacaccc cuugcuggaa acuacacacc uccccucuau gcaccacaaa cacaaaagaa      960

gguuccaaca uaugccuuac cagaacagac agaggcuggu auugcgacaa cgcaggauca     1020

guuucauuuu uuccacaagc ugaaacaugc aaaguacaau caaacagagu cuucugcgac     1080

acaaugaacu caagaacucu acccucagaa guaaaccuau guaacguaga cauuuucaac     1140

cccaaauacg acugcaaaau uaugacauca aaaacagacg uuucaucauc aguuaucacc     1200

ucauuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc aaauaaaugc     1260

agaggaauaa uaaaaacuuu cuccaacgga ugcgacuacg uuucaaacaa agguguagac     1320

acuguaucag uaggaaacac acuauauuac guaaauaaac aagaaggaaa aucacuuuau     1380

gucaaaggag aaccaauaau caauuucuac gacccauuag uauucccauc agacgaauuu     1440

gaugcuucaa uaucacaagu aaacgaaaaa auaaaucaau cacucgcauu uauacgaaaa     1500

ucagacgaac uacuacacaa uguaaacgca ggcaaaucaa caacaaacau aaugauaaca     1560

acaauaauca uuguaauaau aguaauacuu cuaucucuaa uagcaguagg auuacuccuc     1620

uacugcaaag caagaucaac cccuguaaca cuaucaaaag accaacuuuc agguauaaau     1680

aauauagcuu uuuccaauua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5550
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5550
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc uaauccucaa agccaacgcg      120

aucacuacaa uccucacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgag      180

gaguucuacc aaucaaccug cuccgccgua ucaaaaggau accuaagcgc ccuacggacc      240

ggcugguaca caucugucau caccaucgaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggaaccgacg caaaagucaa acugauuaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaacugc aauuacucau gcaaagcaca ccggccaccg gcucaggcag cgccaucgcc      420

uccggcgucg ccgucugcaa aguucuccac cucgagggcg aagucaacaa aauaaaaucu      480

gcccuccucu ccaccaacaa agccgucguc ucccucagcg gcugcggagu cuccguccuc      540

accuucaaag uucucgaucu caagaacuau auugacaaac aacuucuacc cauacucaac      600

aaacaaagcu gcagcauauc caacaucgaa accgucaucg aguuccaaca aaagaacaac      660

cgccuccucg aaauaacccg cgaguucagc guuaacgccg gagucacuac cccugucucc      720

accuacaugc ucaccaacuc cgaacuccua ucacuaauca acgacaugcc cauaaccaac      780

gaccagaaga aacucauguc caacaacguc caaauugucc gacaacaaag cuacuccaua      840

augugcauaa uaaaagagga aguccucgcc uacgucguac aacugccccu uuauggcgua      900

aucgacacac ccugcuggaa acuccacacg ucaccccucu gcaccaccaa cacaaaagaa      960

ggcucgaaca ucugccuaac acggacugac cgcggcuggu acugcgacaa cgccggcucc     1020

gucagcuucu ucccacaagc cgaaaccugc aaaguacaau ccaaccgagu auucugcgac     1080

accaugaacu ccagaacccu ccccucagag gucaaccugu gcaacguaga caucuucaac     1140

cccaaauacg acugcaaaau aaugaccuca aaaacagacg ucuccucuuc cguaaucacc     1200

agccucggag ccaucgucag cugcuacggc aaaaccaaau gcaccgccuc aaacaaaugc     1260

cgcggcauca ucaaaacauu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

acaguaagcg uaggcaacac acuguacuac gucaacaaac aagagggaaa aucacucuac     1380

gucaaaggag aacccauaau caacuucuac gacccccucg uuuuccccag cgacgaguuc     1440

gacgccagca uaucccaagu caacgagaaa auuaaccaau cccuagcauu cauccgaaaa     1500

ucugacgaac ugcuccacaa cgucaacgcg ggaaaaucaa caaccaacau aaugauaacc     1560

acaaucauaa uagucaucau cguaauccuc cucagccuaa ucgcugucgg ccuccuccuc     1620

uacugcaaag cccguuccac cccagucaca cuuuccaagg accaacuaag cggaauaaac     1680

aacaucgcgu ucucaaacua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5551
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5551
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5552
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5552
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccgguccac cccggugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5553
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5553
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5554
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5554
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcucuac accggugacc cugagcaagg accagcucuc cgggauaaac     1680

aauaucgcuu ucucaaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5555
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5555
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5556
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5556
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagauccac accugugacc cuuagcaagg accagcucuc uggaauuaac     1680

aauaucgcgu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5557
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5557
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauacuuaa agccaacgca      120

auaacaacaa uucucacugc ugucaccuuc ugcuucgccu caggccaaaa cauaacggaa      180

gaauuuuacc aaucaacaug cucugcagua uccaaaggcu accuaucugc ucuaagaaca      240

gguugguaua caucaguaau aaccauagaa cuaucaaaca uaaaagaaaa uaaaugcaac      300

ggaacagacg caaaaguuaa acucauaaaa caagaacuag acaaauauaa aaacgcaguu      360

accgaacuac aacuacuuau gcaauccacu cccgccacug gaucaggauc agcaauagca      420

ucaggagucg caguauguaa agucuuacac cucgaaggcg aagucaauaa aaucaaaucc      480

gcauuacuau ccacaaacaa agcagucgua ucccuaagcg gaugcggagu aucaguacua      540

acauuuaaag uacuagaccu aaaaaauuac aucgauaaac aacuauuacc uauauuaaac      600

aaacaauccu gcuccauuuc aaauaucgaa accguaauag aauuucaaca aaaaaacaac      660

agauuacuag aaauaacaag agaauuuucc guaaaugcug gcguaacaac accaguaucc      720

acauacaugc ucacaaacuc cgaacuacua ucacuaauaa augacaugcc cauaacaaac      780

gaucaaaaaa aacuaauguc aaauaaugua caaauaguaa gacaacaaag cuacuccauc      840

auguguauaa uaaaagaaga aguacuagca uacguaguuc aacuaccacu uuacggcgua      900

aucgacaccc cuugcuggaa acuacacacc uccccucuau gcaccacaaa cacaaaagaa      960

gguuccaaca uaugccuuac cagaacagac agaggcuggu auugcgacaa cgcaggauca     1020

guuucauuuu uuccacaagc ugaaacaugc aaaguacaau caaacagagu cuucugcgac     1080

acaaugaacu caagaacucu acccucagaa guaaaccuau guaacguaga cauuuucaac     1140

cccaaauacg acugcaaaau uaugacauca aaaacagacg uuucaucauc aguuaucacc     1200

ucauuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc aaauaaaugc     1260

agaggaauaa uaaaaacuuu cuccaacgga ugcgacuacg uuucaaacaa agguguagac     1320

acuguaucag uaggaaacac acuauauuac guaaauaaac aagaaggaaa aucacuuuau     1380

gucaaaggag aaccaauaau caauuucuac gacccauuag uauucccauc agacgaauuu     1440

gaugcuucaa uaucacaagu aaacgaaaaa auaaaucaau cacucgcauu uauacgaaaa     1500

ucagacgaac uacuacacaa uguaaacgca ggcaaaucaa caacaaacau aaugauaaca     1560

acaauaauca uuguaauaau aguaauacuu cuaucucuaa uagcaguagg auuacuccuc     1620

uacugcaaag caagaucaac cccuguaaca cuaucaaaag accaacuuuc agguauaaau     1680

aauauagcuu uuuccaauua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5558
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5558
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc uaauccucaa agccaacgcg      120

aucacuacaa uccucacagc cgucaccuuc ugcuucgccu ccggccaaaa caucaccgag      180

gaguucuacc aaucaaccug cuccgccgua ucaaaaggau accuaagcgc ccuacggacc      240

ggcugguaca caucugucau caccaucgaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggaaccgacg caaaagucaa acugauuaaa caagaacuag acaaauacaa aaacgcaguc      360

accgaacugc aauuacucau gcaaagcaca ccggccaccg gcucaggcag cgccaucgcc      420

uccggcgucg ccgucugcaa aguucuccac cucgagggcg aagucaacaa aauaaaaucu      480

gcccuccucu ccaccaacaa agccgucguc ucccucagcg gcugcggagu cuccguccuc      540

accuucaaag uucucgaucu caagaacuau auugacaaac aacuucuacc cauacucaac      600

aaacaaagcu gcagcauauc caacaucgaa accgucaucg aguuccaaca aaagaacaac      660

cgccuccucg aaauaacccg cgaguucagc guuaacgccg gagucacuac cccugucucc      720

accuacaugc ucaccaacuc cgaacuccua ucacuaauca acgacaugcc cauaaccaac      780

gaccagaaga aacucauguc caacaacguc caaauugucc gacaacaaag cuacuccaua      840

augugcauaa uaaaagagga aguccucgcc uacgucguac aacugccccu uuauggcgua      900

aucgacacac ccugcuggaa acuccacacg ucaccccucu gcaccaccaa cacaaaagaa      960

ggcucgaaca ucugccuaac acggacugac cgcggcuggu acugcgacaa cgccggcucc     1020

gucagcuucu ucccacaagc cgaaaccugc aaaguacaau ccaaccgagu auucugcgac     1080

accaugaacu ccagaacccu ccccucagag gucaaccugu gcaacguaga caucuucaac     1140

cccaaauacg acugcaaaau aaugaccuca aaaacagacg ucuccucuuc cguaaucacc     1200

agccucggag ccaucgucag cugcuacggc aaaaccaaau gcaccgccuc aaacaaaugc     1260

cgcggcauca ucaaaacauu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

acaguaagcg uaggcaacac acuguacuac gucaacaaac aagagggaaa aucacucuac     1380

gucaaaggag aacccauaau caacuucuac gacccccucg uuuuccccag cgacgaguuc     1440

gacgccagca uaucccaagu caacgagaaa auuaaccaau cccuagcauu cauccgaaaa     1500

ucugacgaac ugcuccacaa cgucaacgcg ggaaaaucaa caaccaacau aaugauaacc     1560

acaaucauaa uagucaucau cguaauccuc cucagccuaa ucgcugucgg ccuccuccuc     1620

uacugcaaag cccguuccac cccagucaca cuuuccaagg accaacuaag cggaauaaac     1680

aacaucgcgu ucucaaacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  5559
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5559
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5560
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5560
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

gguccacccc ggugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5561
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5561
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5562
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5562
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcucuacacc ggugacccug agcaaggacc agcucuccgg gauaaacaau aucgcuuucu     1680

caaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5563
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5563
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5564
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5564
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gauccacacc ugugacccuu agcaaggacc agcucucugg aauuaacaau aucgcguucu     1680

ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5565
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5565
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc      120

ucacugcugu caccuucugc uucgccucag gccaaaacau aacggaagaa uuuuaccaau      180

caacaugcuc ugcaguaucc aaaggcuacc uaucugcucu aagaacaggu ugguauacau      240

caguaauaac cauagaacua ucaaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguuaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac      360

uacuuaugca auccacuccc gccacuggau caggaucagc aauagcauca ggagucgcag      420

uauguaaagu cuuacaccuc gaaggcgaag ucaauaaaau caaauccgca uuacuaucca      480

caaacaaagc agucguaucc cuaagcggau gcggaguauc aguacuaaca uuuaaaguac      540

uagaccuaaa aaauuacauc gauaaacaac uauuaccuau auuaaacaaa caauccugcu      600

ccauuucaaa uaucgaaacc guaauagaau uucaacaaaa aaacaacaga uuacuagaaa      660

uaacaagaga auuuuccgua aaugcuggcg uaacaacacc aguauccaca uacaugcuca      720

caaacuccga acuacuauca cuaauaaaug acaugcccau aacaaacgau caaaaaaaac      780

uaaugucaaa uaauguacaa auaguaagac aacaaagcua cuccaucaug uguauaauaa      840

aagaagaagu acuagcauac guaguucaac uaccacuuua cggcguaauc gacaccccuu      900

gcuggaaacu acacaccucc ccucuaugca ccacaaacac aaaagaaggu uccaacauau      960

gccuuaccag aacagacaga ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc     1020

cacaagcuga aacaugcaaa guacaaucaa acagagucuu cugcgacaca augaacucaa     1080

gaacucuacc cucagaagua aaccuaugua acguagacau uuucaacccc aaauacgacu     1140

gcaaaauuau gacaucaaaa acagacguuu caucaucagu uaucaccuca uuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa     1260

aaacuuucuc caacggaugc gacuacguuu caaacaaagg uguagacacu guaucaguag     1320

gaaacacacu auauuacgua aauaaacaag aaggaaaauc acuuuauguc aaaggagaac     1380

caauaaucaa uuucuacgac ccauuaguau ucccaucaga cgaauuugau gcuucaauau     1440

cacaaguaaa cgaaaaaaua aaucaaucac ucgcauuuau acgaaaauca gacgaacuac     1500

uacacaaugu aaacgcaggc aaaucaacaa caaacauaau gauaacaaca auaaucauug     1560

uaauaauagu aauacuucua ucucuaauag caguaggauu acuccucuac ugcaaagcaa     1620

gaucaacccc uguaacacua ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu     1680

ccaauuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5566
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5566
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuaa uccucaaagc caacgcgauc acuacaaucc      120

ucacagccgu caccuucugc uucgccuccg gccaaaacau caccgaggag uucuaccaau      180

caaccugcuc cgccguauca aaaggauacc uaagcgcccu acggaccggc ugguacacau      240

cugucaucac caucgaacua ucaaacauca aagaaaacaa augcaacgga accgacgcaa      300

aagucaaacu gauuaaacaa gaacuagaca aauacaaaaa cgcagucacc gaacugcaau      360

uacucaugca aagcacaccg gccaccggcu caggcagcgc caucgccucc ggcgucgccg      420

ucugcaaagu ucuccaccuc gagggcgaag ucaacaaaau aaaaucugcc cuccucucca      480

ccaacaaagc cgucgucucc cucagcggcu gcggagucuc cguccucacc uucaaaguuc      540

ucgaucucaa gaacuauauu gacaaacaac uucuacccau acucaacaaa caaagcugca      600

gcauauccaa caucgaaacc gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

uaacccgcga guucagcguu aacgccggag ucacuacccc ugucuccacc uacaugcuca      720

ccaacuccga acuccuauca cuaaucaacg acaugcccau aaccaacgac cagaagaaac      780

ucauguccaa caacguccaa auuguccgac aacaaagcua cuccauaaug ugcauaauaa      840

aagaggaagu ccucgccuac gucguacaac ugccccuuua uggcguaauc gacacacccu      900

gcuggaaacu ccacacguca ccccucugca ccaccaacac aaaagaaggc ucgaacaucu      960

gccuaacacg gacugaccgc ggcugguacu gcgacaacgc cggcuccguc agcuucuucc     1020

cacaagccga aaccugcaaa guacaaucca accgaguauu cugcgacacc augaacucca     1080

gaacccuccc cucagagguc aaccugugca acguagacau cuucaacccc aaauacgacu     1140

gcaaaauaau gaccucaaaa acagacgucu ccucuuccgu aaucaccagc cucggagcca     1200

ucgucagcug cuacggcaaa accaaaugca ccgccucaaa caaaugccgc ggcaucauca     1260

aaacauucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacaca guaagcguag     1320

gcaacacacu guacuacguc aacaaacaag agggaaaauc acucuacguc aaaggagaac     1380

ccauaaucaa cuucuacgac ccccucguuu uccccagcga cgaguucgac gccagcauau     1440

cccaagucaa cgagaaaauu aaccaauccc uagcauucau ccgaaaaucu gacgaacugc     1500

uccacaacgu caacgcggga aaaucaacaa ccaacauaau gauaaccaca aucauaauag     1560

ucaucaucgu aauccuccuc agccuaaucg cugucggccu ccuccucuac ugcaaagccc     1620

guuccacccc agucacacuu uccaaggacc aacuaagcgg aauaaacaac aucgcguucu     1680

caaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  5567
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5567
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5568
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5568
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

gguccacccc ggugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5569
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5569
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5570
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5570
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcucuacacc ggugacccug agcaaggacc agcucuccgg gauaaacaau aucgcuuucu     1680

caaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5571
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5571
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5572
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5572
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gauccacacc ugugacccuu agcaaggacc agcucucugg aauuaacaau aucgcguucu     1680

ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5573
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5573
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc      120

ucacugcugu caccuucugc uucgccucag gccaaaacau aacggaagaa uuuuaccaau      180

caacaugcuc ugcaguaucc aaaggcuacc uaucugcucu aagaacaggu ugguauacau      240

caguaauaac cauagaacua ucaaacauaa aagaaaauaa augcaacgga acagacgcaa      300

aaguuaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac      360

uacuuaugca auccacuccc gccacuggau caggaucagc aauagcauca ggagucgcag      420

uauguaaagu cuuacaccuc gaaggcgaag ucaauaaaau caaauccgca uuacuaucca      480

caaacaaagc agucguaucc cuaagcggau gcggaguauc aguacuaaca uuuaaaguac      540

uagaccuaaa aaauuacauc gauaaacaac uauuaccuau auuaaacaaa caauccugcu      600

ccauuucaaa uaucgaaacc guaauagaau uucaacaaaa aaacaacaga uuacuagaaa      660

uaacaagaga auuuuccgua aaugcuggcg uaacaacacc aguauccaca uacaugcuca      720

caaacuccga acuacuauca cuaauaaaug acaugcccau aacaaacgau caaaaaaaac      780

uaaugucaaa uaauguacaa auaguaagac aacaaagcua cuccaucaug uguauaauaa      840

aagaagaagu acuagcauac guaguucaac uaccacuuua cggcguaauc gacaccccuu      900

gcuggaaacu acacaccucc ccucuaugca ccacaaacac aaaagaaggu uccaacauau      960

gccuuaccag aacagacaga ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc     1020

cacaagcuga aacaugcaaa guacaaucaa acagagucuu cugcgacaca augaacucaa     1080

gaacucuacc cucagaagua aaccuaugua acguagacau uuucaacccc aaauacgacu     1140

gcaaaauuau gacaucaaaa acagacguuu caucaucagu uaucaccuca uuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa     1260

aaacuuucuc caacggaugc gacuacguuu caaacaaagg uguagacacu guaucaguag     1320

gaaacacacu auauuacgua aauaaacaag aaggaaaauc acuuuauguc aaaggagaac     1380

caauaaucaa uuucuacgac ccauuaguau ucccaucaga cgaauuugau gcuucaauau     1440

cacaaguaaa cgaaaaaaua aaucaaucac ucgcauuuau acgaaaauca gacgaacuac     1500

uacacaaugu aaacgcaggc aaaucaacaa caaacauaau gauaacaaca auaaucauug     1560

uaauaauagu aauacuucua ucucuaauag caguaggauu acuccucuac ugcaaagcaa     1620

gaucaacccc uguaacacua ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu     1680

ccaauuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5574
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5574
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuaa uccucaaagc caacgcgauc acuacaaucc      120

ucacagccgu caccuucugc uucgccuccg gccaaaacau caccgaggag uucuaccaau      180

caaccugcuc cgccguauca aaaggauacc uaagcgcccu acggaccggc ugguacacau      240

cugucaucac caucgaacua ucaaacauca aagaaaacaa augcaacgga accgacgcaa      300

aagucaaacu gauuaaacaa gaacuagaca aauacaaaaa cgcagucacc gaacugcaau      360

uacucaugca aagcacaccg gccaccggcu caggcagcgc caucgccucc ggcgucgccg      420

ucugcaaagu ucuccaccuc gagggcgaag ucaacaaaau aaaaucugcc cuccucucca      480

ccaacaaagc cgucgucucc cucagcggcu gcggagucuc cguccucacc uucaaaguuc      540

ucgaucucaa gaacuauauu gacaaacaac uucuacccau acucaacaaa caaagcugca      600

gcauauccaa caucgaaacc gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

uaacccgcga guucagcguu aacgccggag ucacuacccc ugucuccacc uacaugcuca      720

ccaacuccga acuccuauca cuaaucaacg acaugcccau aaccaacgac cagaagaaac      780

ucauguccaa caacguccaa auuguccgac aacaaagcua cuccauaaug ugcauaauaa      840

aagaggaagu ccucgccuac gucguacaac ugccccuuua uggcguaauc gacacacccu      900

gcuggaaacu ccacacguca ccccucugca ccaccaacac aaaagaaggc ucgaacaucu      960

gccuaacacg gacugaccgc ggcugguacu gcgacaacgc cggcuccguc agcuucuucc     1020

cacaagccga aaccugcaaa guacaaucca accgaguauu cugcgacacc augaacucca     1080

gaacccuccc cucagagguc aaccugugca acguagacau cuucaacccc aaauacgacu     1140

gcaaaauaau gaccucaaaa acagacgucu ccucuuccgu aaucaccagc cucggagcca     1200

ucgucagcug cuacggcaaa accaaaugca ccgccucaaa caaaugccgc ggcaucauca     1260

aaacauucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacaca guaagcguag     1320

gcaacacacu guacuacguc aacaaacaag agggaaaauc acucuacguc aaaggagaac     1380

ccauaaucaa cuucuacgac ccccucguuu uccccagcga cgaguucgac gccagcauau     1440

cccaagucaa cgagaaaauu aaccaauccc uagcauucau ccgaaaaucu gacgaacugc     1500

uccacaacgu caacgcggga aaaucaacaa ccaacauaau gauaaccaca aucauaauag     1560

ucaucaucgu aauccuccuc agccuaaucg cugucggccu ccuccucuac ugcaaagccc     1620

guuccacccc agucacacuu uccaaggacc aacuaagcgg aauaaacaac aucgcguucu     1680

caaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  5575
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5575
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5576
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5576
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccgguccacc     1620

ccggugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5577
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5577
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5578
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5578
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcucuaca     1620

ccggugaccc ugagcaagga ccagcucucc gggauaaaca auaucgcuuu cucaaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5579
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5579
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5580
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5580
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagauccaca     1620

ccugugaccc uuagcaagga ccagcucucu ggaauuaaca auaucgcguu cuccaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5581
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5581
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuuaaa gccaacgcaa uaacaacaau ucucacugcu      120

gucaccuucu gcuucgccuc aggccaaaac auaacggaag aauuuuacca aucaacaugc      180

ucugcaguau ccaaaggcua ccuaucugcu cuaagaacag guugguauac aucaguaaua      240

accauagaac uaucaaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguuaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguua ccgaacuaca acuacuuaug      360

caauccacuc ccgccacugg aucaggauca gcaauagcau caggagucgc aguauguaaa      420

gucuuacacc ucgaaggcga agucaauaaa aucaaauccg cauuacuauc cacaaacaaa      480

gcagucguau cccuaagcgg augcggagua ucaguacuaa cauuuaaagu acuagaccua      540

aaaaauuaca ucgauaaaca acuauuaccu auauuaaaca aacaauccug cuccauuuca      600

aauaucgaaa ccguaauaga auuucaacaa aaaaacaaca gauuacuaga aauaacaaga      660

gaauuuuccg uaaaugcugg cguaacaaca ccaguaucca cauacaugcu cacaaacucc      720

gaacuacuau cacuaauaaa ugacaugccc auaacaaacg aucaaaaaaa acuaauguca      780

aauaauguac aaauaguaag acaacaaagc uacuccauca uguguauaau aaaagaagaa      840

guacuagcau acguaguuca acuaccacuu uacggcguaa ucgacacccc uugcuggaaa      900

cuacacaccu ccccucuaug caccacaaac acaaaagaag guuccaacau augccuuacc      960

agaacagaca gaggcuggua uugcgacaac gcaggaucag uuucauuuuu uccacaagcu     1020

gaaacaugca aaguacaauc aaacagaguc uucugcgaca caaugaacuc aagaacucua     1080

cccucagaag uaaaccuaug uaacguagac auuuucaacc ccaaauacga cugcaaaauu     1140

augacaucaa aaacagacgu uucaucauca guuaucaccu cauuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccuca aauaaaugca gaggaauaau aaaaacuuuc     1260

uccaacggau gcgacuacgu uucaaacaaa gguguagaca cuguaucagu aggaaacaca     1320

cuauauuacg uaaauaaaca agaaggaaaa ucacuuuaug ucaaaggaga accaauaauc     1380

aauuucuacg acccauuagu auucccauca gacgaauuug augcuucaau aucacaagua     1440

aacgaaaaaa uaaaucaauc acucgcauuu auacgaaaau cagacgaacu acuacacaau     1500

guaaacgcag gcaaaucaac aacaaacaua augauaacaa caauaaucau uguaauaaua     1560

guaauacuuc uaucucuaau agcaguagga uuacuccucu acugcaaagc aagaucaacc     1620

ccuguaacac uaucaaaaga ccaacuuuca gguauaaaua auauagcuuu uuccaauuaa     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5582
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5582
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu aauccucaaa gccaacgcga ucacuacaau ccucacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgagg aguucuacca aucaaccugc      180

uccgccguau caaaaggaua ccuaagcgcc cuacggaccg gcugguacac aucugucauc      240

accaucgaac uaucaaacau caaagaaaac aaaugcaacg gaaccgacgc aaaagucaaa      300

cugauuaaac aagaacuaga caaauacaaa aacgcaguca ccgaacugca auuacucaug      360

caaagcacac cggccaccgg cucaggcagc gccaucgccu ccggcgucgc cgucugcaaa      420

guucuccacc ucgagggcga agucaacaaa auaaaaucug cccuccucuc caccaacaaa      480

gccgucgucu cccucagcgg cugcggaguc uccguccuca ccuucaaagu ucucgaucuc      540

aagaacuaua uugacaaaca acuucuaccc auacucaaca aacaaagcug cagcauaucc      600

aacaucgaaa ccgucaucga guuccaacaa aagaacaacc gccuccucga aauaacccgc      660

gaguucagcg uuaacgccgg agucacuacc ccugucucca ccuacaugcu caccaacucc      720

gaacuccuau cacuaaucaa cgacaugccc auaaccaacg accagaagaa acucaugucc      780

aacaacgucc aaauuguccg acaacaaagc uacuccauaa ugugcauaau aaaagaggaa      840

guccucgccu acgucguaca acugccccuu uauggcguaa ucgacacacc cugcuggaaa      900

cuccacacgu caccccucug caccaccaac acaaaagaag gcucgaacau cugccuaaca      960

cggacugacc gcggcuggua cugcgacaac gccggcuccg ucagcuucuu cccacaagcc     1020

gaaaccugca aaguacaauc caaccgagua uucugcgaca ccaugaacuc cagaacccuc     1080

cccucagagg ucaaccugug caacguagac aucuucaacc ccaaauacga cugcaaaaua     1140

augaccucaa aaacagacgu cuccucuucc guaaucacca gccucggagc caucgucagc     1200

ugcuacggca aaaccaaaug caccgccuca aacaaaugcc gcggcaucau caaaacauuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca caguaagcgu aggcaacaca     1320

cuguacuacg ucaacaaaca agagggaaaa ucacucuacg ucaaaggaga acccauaauc     1380

aacuucuacg acccccucgu uuuccccagc gacgaguucg acgccagcau aucccaaguc     1440

aacgagaaaa uuaaccaauc ccuagcauuc auccgaaaau cugacgaacu gcuccacaac     1500

gucaacgcgg gaaaaucaac aaccaacaua augauaacca caaucauaau agucaucauc     1560

guaauccucc ucagccuaau cgcugucggc cuccuccucu acugcaaagc ccguuccacc     1620

ccagucacac uuuccaagga ccaacuaagc ggaauaaaca acaucgcguu cucaaacuaa     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  5583
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5583
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5584
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5584
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccgguccacc     1620

ccggugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5585
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5585
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5586
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5586
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcucuaca     1620

ccggugaccc ugagcaagga ccagcucucc gggauaaaca auaucgcuuu cucaaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5587
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5587
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5588
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5588
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagauccaca     1620

ccugugaccc uuagcaagga ccagcucucu ggaauuaaca auaucgcguu cuccaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5589
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5589
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauacuuaaa gccaacgcaa uaacaacaau ucucacugcu      120

gucaccuucu gcuucgccuc aggccaaaac auaacggaag aauuuuacca aucaacaugc      180

ucugcaguau ccaaaggcua ccuaucugcu cuaagaacag guugguauac aucaguaaua      240

accauagaac uaucaaacau aaaagaaaau aaaugcaacg gaacagacgc aaaaguuaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguua ccgaacuaca acuacuuaug      360

caauccacuc ccgccacugg aucaggauca gcaauagcau caggagucgc aguauguaaa      420

gucuuacacc ucgaaggcga agucaauaaa aucaaauccg cauuacuauc cacaaacaaa      480

gcagucguau cccuaagcgg augcggagua ucaguacuaa cauuuaaagu acuagaccua      540

aaaaauuaca ucgauaaaca acuauuaccu auauuaaaca aacaauccug cuccauuuca      600

aauaucgaaa ccguaauaga auuucaacaa aaaaacaaca gauuacuaga aauaacaaga      660

gaauuuuccg uaaaugcugg cguaacaaca ccaguaucca cauacaugcu cacaaacucc      720

gaacuacuau cacuaauaaa ugacaugccc auaacaaacg aucaaaaaaa acuaauguca      780

aauaauguac aaauaguaag acaacaaagc uacuccauca uguguauaau aaaagaagaa      840

guacuagcau acguaguuca acuaccacuu uacggcguaa ucgacacccc uugcuggaaa      900

cuacacaccu ccccucuaug caccacaaac acaaaagaag guuccaacau augccuuacc      960

agaacagaca gaggcuggua uugcgacaac gcaggaucag uuucauuuuu uccacaagcu     1020

gaaacaugca aaguacaauc aaacagaguc uucugcgaca caaugaacuc aagaacucua     1080

cccucagaag uaaaccuaug uaacguagac auuuucaacc ccaaauacga cugcaaaauu     1140

augacaucaa aaacagacgu uucaucauca guuaucaccu cauuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccuca aauaaaugca gaggaauaau aaaaacuuuc     1260

uccaacggau gcgacuacgu uucaaacaaa gguguagaca cuguaucagu aggaaacaca     1320

cuauauuacg uaaauaaaca agaaggaaaa ucacuuuaug ucaaaggaga accaauaauc     1380

aauuucuacg acccauuagu auucccauca gacgaauuug augcuucaau aucacaagua     1440

aacgaaaaaa uaaaucaauc acucgcauuu auacgaaaau cagacgaacu acuacacaau     1500

guaaacgcag gcaaaucaac aacaaacaua augauaacaa caauaaucau uguaauaaua     1560

guaauacuuc uaucucuaau agcaguagga uuacuccucu acugcaaagc aagaucaacc     1620

ccuguaacac uaucaaaaga ccaacuuuca gguauaaaua auauagcuuu uuccaauuaa     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5590
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5590
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu aauccucaaa gccaacgcga ucacuacaau ccucacagcc      120

gucaccuucu gcuucgccuc cggccaaaac aucaccgagg aguucuacca aucaaccugc      180

uccgccguau caaaaggaua ccuaagcgcc cuacggaccg gcugguacac aucugucauc      240

accaucgaac uaucaaacau caaagaaaac aaaugcaacg gaaccgacgc aaaagucaaa      300

cugauuaaac aagaacuaga caaauacaaa aacgcaguca ccgaacugca auuacucaug      360

caaagcacac cggccaccgg cucaggcagc gccaucgccu ccggcgucgc cgucugcaaa      420

guucuccacc ucgagggcga agucaacaaa auaaaaucug cccuccucuc caccaacaaa      480

gccgucgucu cccucagcgg cugcggaguc uccguccuca ccuucaaagu ucucgaucuc      540

aagaacuaua uugacaaaca acuucuaccc auacucaaca aacaaagcug cagcauaucc      600

aacaucgaaa ccgucaucga guuccaacaa aagaacaacc gccuccucga aauaacccgc      660

gaguucagcg uuaacgccgg agucacuacc ccugucucca ccuacaugcu caccaacucc      720

gaacuccuau cacuaaucaa cgacaugccc auaaccaacg accagaagaa acucaugucc      780

aacaacgucc aaauuguccg acaacaaagc uacuccauaa ugugcauaau aaaagaggaa      840

guccucgccu acgucguaca acugccccuu uauggcguaa ucgacacacc cugcuggaaa      900

cuccacacgu caccccucug caccaccaac acaaaagaag gcucgaacau cugccuaaca      960

cggacugacc gcggcuggua cugcgacaac gccggcuccg ucagcuucuu cccacaagcc     1020

gaaaccugca aaguacaauc caaccgagua uucugcgaca ccaugaacuc cagaacccuc     1080

cccucagagg ucaaccugug caacguagac aucuucaacc ccaaauacga cugcaaaaua     1140

augaccucaa aaacagacgu cuccucuucc guaaucacca gccucggagc caucgucagc     1200

ugcuacggca aaaccaaaug caccgccuca aacaaaugcc gcggcaucau caaaacauuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca caguaagcgu aggcaacaca     1320

cuguacuacg ucaacaaaca agagggaaaa ucacucuacg ucaaaggaga acccauaauc     1380

aacuucuacg acccccucgu uuuccccagc gacgaguucg acgccagcau aucccaaguc     1440

aacgagaaaa uuaaccaauc ccuagcauuc auccgaaaau cugacgaacu gcuccacaac     1500

gucaacgcgg gaaaaucaac aaccaacaua augauaacca caaucauaau agucaucauc     1560

guaauccucc ucagccuaau cgcugucggc cuccuccucu acugcaaagc ccguuccacc     1620

ccagucacac uuuccaagga ccaacuaagc ggaauaaaca acaucgcguu cucaaacuaa     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  5591
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5591
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5592
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5592
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5593
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5593
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5594
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5594
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggg     1680

auaaacaaua ucgcuuucuc aaacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5595
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5595
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5596
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5596
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucugga     1680

auuaacaaua ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5597
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5597
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuuaaagcc      120

aacgcaauaa caacaauucu cacugcuguc accuucugcu ucgccucagg ccaaaacaua      180

acggaagaau uuuaccaauc aacaugcucu gcaguaucca aaggcuaccu aucugcucua      240

agaacagguu gguauacauc aguaauaacc auagaacuau caaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguuaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguuaccg aacuacaacu acuuaugcaa uccacucccg ccacuggauc aggaucagca      420

auagcaucag gagucgcagu auguaaaguc uuacaccucg aaggcgaagu caauaaaauc      480

aaauccgcau uacuauccac aaacaaagca gucguauccc uaagcggaug cggaguauca      540

guacuaacau uuaaaguacu agaccuaaaa aauuacaucg auaaacaacu auuaccuaua      600

uuaaacaaac aauccugcuc cauuucaaau aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagau uacuagaaau aacaagagaa uuuuccguaa augcuggcgu aacaacacca      720

guauccacau acaugcucac aaacuccgaa cuacuaucac uaauaaauga caugcccaua      780

acaaacgauc aaaaaaaacu aaugucaaau aauguacaaa uaguaagaca acaaagcuac      840

uccaucaugu guauaauaaa agaagaagua cuagcauacg uaguucaacu accacuuuac      900

ggcguaaucg acaccccuug cuggaaacua cacaccuccc cucuaugcac cacaaacaca      960

aaagaagguu ccaacauaug ccuuaccaga acagacagag gcugguauug cgacaacgca     1020

ggaucaguuu cauuuuuucc acaagcugaa acaugcaaag uacaaucaaa cagagucuuc     1080

ugcgacacaa ugaacucaag aacucuaccc ucagaaguaa accuauguaa cguagacauu     1140

uucaacccca aauacgacug caaaauuaug acaucaaaaa cagacguuuc aucaucaguu     1200

aucaccucau uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucaaau     1260

aaaugcagag gaauaauaaa aacuuucucc aacggaugcg acuacguuuc aaacaaaggu     1320

guagacacug uaucaguagg aaacacacua uauuacguaa auaaacaaga aggaaaauca     1380

cuuuauguca aaggagaacc aauaaucaau uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug cuucaauauc acaaguaaac gaaaaaauaa aucaaucacu cgcauuuaua     1500

cgaaaaucag acgaacuacu acacaaugua aacgcaggca aaucaacaac aaacauaaug     1560

auaacaacaa uaaucauugu aauaauagua auacuucuau cucuaauagc aguaggauua     1620

cuccucuacu gcaaagcaag aucaaccccu guaacacuau caaaagacca acuuucaggu     1680

auaaauaaua uagcuuuuuc caauuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5598
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5598
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccuaau ccucaaagcc      120

aacgcgauca cuacaauccu cacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaggagu ucuaccaauc aaccugcucc gccguaucaa aaggauaccu aagcgcccua      240

cggaccggcu gguacacauc ugucaucacc aucgaacuau caaacaucaa agaaaacaaa      300

ugcaacggaa ccgacgcaaa agucaaacug auuaaacaag aacuagacaa auacaaaaac      360

gcagucaccg aacugcaauu acucaugcaa agcacaccgg ccaccggcuc aggcagcgcc      420

aucgccuccg gcgucgccgu cugcaaaguu cuccaccucg agggcgaagu caacaaaaua      480

aaaucugccc uccucuccac caacaaagcc gucgucuccc ucagcggcug cggagucucc      540

guccucaccu ucaaaguucu cgaucucaag aacuauauug acaaacaacu ucuacccaua      600

cucaacaaac aaagcugcag cauauccaac aucgaaaccg ucaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau aacccgcgag uucagcguua acgccggagu cacuaccccu      720

gucuccaccu acaugcucac caacuccgaa cuccuaucac uaaucaacga caugcccaua      780

accaacgacc agaagaaacu cauguccaac aacguccaaa uuguccgaca acaaagcuac      840

uccauaaugu gcauaauaaa agaggaaguc cucgccuacg ucguacaacu gccccuuuau      900

ggcguaaucg acacacccug cuggaaacuc cacacgucac cccucugcac caccaacaca      960

aaagaaggcu cgaacaucug ccuaacacgg acugaccgcg gcugguacug cgacaacgcc     1020

ggcuccguca gcuucuuccc acaagccgaa accugcaaag uacaauccaa ccgaguauuc     1080

ugcgacacca ugaacuccag aacccucccc ucagagguca accugugcaa cguagacauc     1140

uucaacccca aauacgacug caaaauaaug accucaaaaa cagacgucuc cucuuccgua     1200

aucaccagcc ucggagccau cgucagcugc uacggcaaaa ccaaaugcac cgccucaaac     1260

aaaugccgcg gcaucaucaa aacauucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag uaagcguagg caacacacug uacuacguca acaaacaaga gggaaaauca     1380

cucuacguca aaggagaacc cauaaucaac uucuacgacc cccucguuuu ccccagcgac     1440

gaguucgacg ccagcauauc ccaagucaac gagaaaauua accaaucccu agcauucauc     1500

cgaaaaucug acgaacugcu ccacaacguc aacgcgggaa aaucaacaac caacauaaug     1560

auaaccacaa ucauaauagu caucaucgua auccuccuca gccuaaucgc ugucggccuc     1620

cuccucuacu gcaaagcccg uuccacccca gucacacuuu ccaaggacca acuaagcgga     1680

auaaacaaca ucgcguucuc aaacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  5599
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5599
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5600
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5600
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg guccaccccg gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5601
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5601
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5602
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5602
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cucuacaccg gugacccuga gcaaggacca gcucuccggg     1680

auaaacaaua ucgcuuucuc aaacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5603
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5603
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5604
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5604
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag auccacaccu gugacccuua gcaaggacca gcucucugga     1680

auuaacaaua ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5605
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5605
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau acuuaaagcc      120

aacgcaauaa caacaauucu cacugcuguc accuucugcu ucgccucagg ccaaaacaua      180

acggaagaau uuuaccaauc aacaugcucu gcaguaucca aaggcuaccu aucugcucua      240

agaacagguu gguauacauc aguaauaacc auagaacuau caaacauaaa agaaaauaaa      300

ugcaacggaa cagacgcaaa aguuaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguuaccg aacuacaacu acuuaugcaa uccacucccg ccacuggauc aggaucagca      420

auagcaucag gagucgcagu auguaaaguc uuacaccucg aaggcgaagu caauaaaauc      480

aaauccgcau uacuauccac aaacaaagca gucguauccc uaagcggaug cggaguauca      540

guacuaacau uuaaaguacu agaccuaaaa aauuacaucg auaaacaacu auuaccuaua      600

uuaaacaaac aauccugcuc cauuucaaau aucgaaaccg uaauagaauu ucaacaaaaa      660

aacaacagau uacuagaaau aacaagagaa uuuuccguaa augcuggcgu aacaacacca      720

guauccacau acaugcucac aaacuccgaa cuacuaucac uaauaaauga caugcccaua      780

acaaacgauc aaaaaaaacu aaugucaaau aauguacaaa uaguaagaca acaaagcuac      840

uccaucaugu guauaauaaa agaagaagua cuagcauacg uaguucaacu accacuuuac      900

ggcguaaucg acaccccuug cuggaaacua cacaccuccc cucuaugcac cacaaacaca      960

aaagaagguu ccaacauaug ccuuaccaga acagacagag gcugguauug cgacaacgca     1020

ggaucaguuu cauuuuuucc acaagcugaa acaugcaaag uacaaucaaa cagagucuuc     1080

ugcgacacaa ugaacucaag aacucuaccc ucagaaguaa accuauguaa cguagacauu     1140

uucaacccca aauacgacug caaaauuaug acaucaaaaa cagacguuuc aucaucaguu     1200

aucaccucau uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucaaau     1260

aaaugcagag gaauaauaaa aacuuucucc aacggaugcg acuacguuuc aaacaaaggu     1320

guagacacug uaucaguagg aaacacacua uauuacguaa auaaacaaga aggaaaauca     1380

cuuuauguca aaggagaacc aauaaucaau uucuacgacc cauuaguauu cccaucagac     1440

gaauuugaug cuucaauauc acaaguaaac gaaaaaauaa aucaaucacu cgcauuuaua     1500

cgaaaaucag acgaacuacu acacaaugua aacgcaggca aaucaacaac aaacauaaug     1560

auaacaacaa uaaucauugu aauaauagua auacuucuau cucuaauagc aguaggauua     1620

cuccucuacu gcaaagcaag aucaaccccu guaacacuau caaaagacca acuuucaggu     1680

auaaauaaua uagcuuuuuc caauuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5606
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5606
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccuaau ccucaaagcc      120

aacgcgauca cuacaauccu cacagccguc accuucugcu ucgccuccgg ccaaaacauc      180

accgaggagu ucuaccaauc aaccugcucc gccguaucaa aaggauaccu aagcgcccua      240

cggaccggcu gguacacauc ugucaucacc aucgaacuau caaacaucaa agaaaacaaa      300

ugcaacggaa ccgacgcaaa agucaaacug auuaaacaag aacuagacaa auacaaaaac      360

gcagucaccg aacugcaauu acucaugcaa agcacaccgg ccaccggcuc aggcagcgcc      420

aucgccuccg gcgucgccgu cugcaaaguu cuccaccucg agggcgaagu caacaaaaua      480

aaaucugccc uccucuccac caacaaagcc gucgucuccc ucagcggcug cggagucucc      540

guccucaccu ucaaaguucu cgaucucaag aacuauauug acaaacaacu ucuacccaua      600

cucaacaaac aaagcugcag cauauccaac aucgaaaccg ucaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau aacccgcgag uucagcguua acgccggagu cacuaccccu      720

gucuccaccu acaugcucac caacuccgaa cuccuaucac uaaucaacga caugcccaua      780

accaacgacc agaagaaacu cauguccaac aacguccaaa uuguccgaca acaaagcuac      840

uccauaaugu gcauaauaaa agaggaaguc cucgccuacg ucguacaacu gccccuuuau      900

ggcguaaucg acacacccug cuggaaacuc cacacgucac cccucugcac caccaacaca      960

aaagaaggcu cgaacaucug ccuaacacgg acugaccgcg gcugguacug cgacaacgcc     1020

ggcuccguca gcuucuuccc acaagccgaa accugcaaag uacaauccaa ccgaguauuc     1080

ugcgacacca ugaacuccag aacccucccc ucagagguca accugugcaa cguagacauc     1140

uucaacccca aauacgacug caaaauaaug accucaaaaa cagacgucuc cucuuccgua     1200

aucaccagcc ucggagccau cgucagcugc uacggcaaaa ccaaaugcac cgccucaaac     1260

aaaugccgcg gcaucaucaa aacauucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacacag uaagcguagg caacacacug uacuacguca acaaacaaga gggaaaauca     1380

cucuacguca aaggagaacc cauaaucaac uucuacgacc cccucguuuu ccccagcgac     1440

gaguucgacg ccagcauauc ccaagucaac gagaaaauua accaaucccu agcauucauc     1500

cgaaaaucug acgaacugcu ccacaacguc aacgcgggaa aaucaacaac caacauaaug     1560

auaaccacaa ucauaauagu caucaucgua auccuccuca gccuaaucgc ugucggccuc     1620

cuccucuacu gcaaagcccg uuccacccca gucacacuuu ccaaggacca acuaagcgga     1680

auaaacaaca ucgcguucuc aaacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5607
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5607
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5608
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5608
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccgguc caccccggug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5609
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5609
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5610
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5610
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcuc uacaccggug     1680

acccugagca aggaccagcu cuccgggaua aacaauaucg cuuucucaaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5611
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5611
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5612
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5612
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagauc cacaccugug     1680

acccuuagca aggaccagcu cucuggaauu aacaauaucg cguucuccaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5613
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5613
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauacu uaaagccaac gcaauaacaa caauucucac ugcugucacc      180

uucugcuucg ccucaggcca aaacauaacg gaagaauuuu accaaucaac augcucugca      240

guauccaaag gcuaccuauc ugcucuaaga acagguuggu auacaucagu aauaaccaua      300

gaacuaucaa acauaaaaga aaauaaaugc aacggaacag acgcaaaagu uaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guuaccgaac uacaacuacu uaugcaaucc      420

acucccgcca cuggaucagg aucagcaaua gcaucaggag ucgcaguaug uaaagucuua      480

caccucgaag gcgaagucaa uaaaaucaaa uccgcauuac uauccacaaa caaagcaguc      540

guaucccuaa gcggaugcgg aguaucagua cuaacauuua aaguacuaga ccuaaaaaau      600

uacaucgaua aacaacuauu accuauauua aacaaacaau ccugcuccau uucaaauauc      660

gaaaccguaa uagaauuuca acaaaaaaac aacagauuac uagaaauaac aagagaauuu      720

uccguaaaug cuggcguaac aacaccagua uccacauaca ugcucacaaa cuccgaacua      780

cuaucacuaa uaaaugacau gcccauaaca aacgaucaaa aaaaacuaau gucaaauaau      840

guacaaauag uaagacaaca aagcuacucc aucaugugua uaauaaaaga agaaguacua      900

gcauacguag uucaacuacc acuuuacggc guaaucgaca ccccuugcug gaaacuacac      960

accuccccuc uaugcaccac aaacacaaaa gaagguucca acauaugccu uaccagaaca     1020

gacagaggcu gguauugcga caacgcagga ucaguuucau uuuuuccaca agcugaaaca     1080

ugcaaaguac aaucaaacag agucuucugc gacacaauga acucaagaac ucuacccuca     1140

gaaguaaacc uauguaacgu agacauuuuc aaccccaaau acgacugcaa aauuaugaca     1200

ucaaaaacag acguuucauc aucaguuauc accucauuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucaaauaaa ugcagaggaa uaauaaaaac uuucuccaac     1320

ggaugcgacu acguuucaaa caaaggugua gacacuguau caguaggaaa cacacuauau     1380

uacguaaaua aacaagaagg aaaaucacuu uaugucaaag gagaaccaau aaucaauuuc     1440

uacgacccau uaguauuccc aucagacgaa uuugaugcuu caauaucaca aguaaacgaa     1500

aaaauaaauc aaucacucgc auuuauacga aaaucagacg aacuacuaca caauguaaac     1560

gcaggcaaau caacaacaaa cauaaugaua acaacaauaa ucauuguaau aauaguaaua     1620

cuucuaucuc uaauagcagu aggauuacuc cucuacugca aagcaagauc aaccccugua     1680

acacuaucaa aagaccaacu uucagguaua aauaauauag cuuuuuccaa uuaaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5614
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5614
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccuaauccu caaagccaac gcgaucacua caauccucac agccgucacc      180

uucugcuucg ccuccggcca aaacaucacc gaggaguucu accaaucaac cugcuccgcc      240

guaucaaaag gauaccuaag cgcccuacgg accggcuggu acacaucugu caucaccauc      300

gaacuaucaa acaucaaaga aaacaaaugc aacggaaccg acgcaaaagu caaacugauu      360

aaacaagaac uagacaaaua caaaaacgca gucaccgaac ugcaauuacu caugcaaagc      420

acaccggcca ccggcucagg cagcgccauc gccuccggcg ucgccgucug caaaguucuc      480

caccucgagg gcgaagucaa caaaauaaaa ucugcccucc ucuccaccaa caaagccguc      540

gucucccuca gcggcugcgg agucuccguc cucaccuuca aaguucucga ucucaagaac      600

uauauugaca aacaacuucu acccauacuc aacaaacaaa gcugcagcau auccaacauc      660

gaaaccguca ucgaguucca acaaaagaac aaccgccucc ucgaaauaac ccgcgaguuc      720

agcguuaacg ccggagucac uaccccuguc uccaccuaca ugcucaccaa cuccgaacuc      780

cuaucacuaa ucaacgacau gcccauaacc aacgaccaga agaaacucau guccaacaac      840

guccaaauug uccgacaaca aagcuacucc auaaugugca uaauaaaaga ggaaguccuc      900

gccuacgucg uacaacugcc ccuuuauggc guaaucgaca cacccugcug gaaacuccac      960

acgucacccc ucugcaccac caacacaaaa gaaggcucga acaucugccu aacacggacu     1020

gaccgcggcu gguacugcga caacgccggc uccgucagcu ucuucccaca agccgaaacc     1080

ugcaaaguac aauccaaccg aguauucugc gacaccauga acuccagaac ccuccccuca     1140

gaggucaacc ugugcaacgu agacaucuuc aaccccaaau acgacugcaa aauaaugacc     1200

ucaaaaacag acgucuccuc uuccguaauc accagccucg gagccaucgu cagcugcuac     1260

ggcaaaacca aaugcaccgc cucaaacaaa ugccgcggca ucaucaaaac auucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacacaguaa gcguaggcaa cacacuguac     1380

uacgucaaca aacaagaggg aaaaucacuc uacgucaaag gagaacccau aaucaacuuc     1440

uacgaccccc ucguuuuccc cagcgacgag uucgacgcca gcauauccca agucaacgag     1500

aaaauuaacc aaucccuagc auucauccga aaaucugacg aacugcucca caacgucaac     1560

gcgggaaaau caacaaccaa cauaaugaua accacaauca uaauagucau caucguaauc     1620

cuccucagcc uaaucgcugu cggccuccuc cucuacugca aagcccguuc caccccaguc     1680

acacuuucca aggaccaacu aagcggaaua aacaacaucg cguucucaaa cuaaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5615
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5615
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5616
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5616
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccgguccacc ccggugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5617
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5617
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5618
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5618
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcucuaca ccggugaccc ugagcaagga ccagcucucc     1680

gggauaaaca auaucgcuuu cucaaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5619
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5619
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5620
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5620
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagauccaca ccugugaccc uuagcaagga ccagcucucu     1680

ggaauuaaca auaucgcguu cuccaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5621
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5621
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuuaaa      120

gccaacgcaa uaacaacaau ucucacugcu gucaccuucu gcuucgccuc aggccaaaac      180

auaacggaag aauuuuacca aucaacaugc ucugcaguau ccaaaggcua ccuaucugcu      240

cuaagaacag guugguauac aucaguaaua accauagaac uaucaaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguuaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguua ccgaacuaca acuacuuaug caauccacuc ccgccacugg aucaggauca      420

gcaauagcau caggagucgc aguauguaaa gucuuacacc ucgaaggcga agucaauaaa      480

aucaaauccg cauuacuauc cacaaacaaa gcagucguau cccuaagcgg augcggagua      540

ucaguacuaa cauuuaaagu acuagaccua aaaaauuaca ucgauaaaca acuauuaccu      600

auauuaaaca aacaauccug cuccauuuca aauaucgaaa ccguaauaga auuucaacaa      660

aaaaacaaca gauuacuaga aauaacaaga gaauuuuccg uaaaugcugg cguaacaaca      720

ccaguaucca cauacaugcu cacaaacucc gaacuacuau cacuaauaaa ugacaugccc      780

auaacaaacg aucaaaaaaa acuaauguca aauaauguac aaauaguaag acaacaaagc      840

uacuccauca uguguauaau aaaagaagaa guacuagcau acguaguuca acuaccacuu      900

uacggcguaa ucgacacccc uugcuggaaa cuacacaccu ccccucuaug caccacaaac      960

acaaaagaag guuccaacau augccuuacc agaacagaca gaggcuggua uugcgacaac     1020

gcaggaucag uuucauuuuu uccacaagcu gaaacaugca aaguacaauc aaacagaguc     1080

uucugcgaca caaugaacuc aagaacucua cccucagaag uaaaccuaug uaacguagac     1140

auuuucaacc ccaaauacga cugcaaaauu augacaucaa aaacagacgu uucaucauca     1200

guuaucaccu cauuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccuca     1260

aauaaaugca gaggaauaau aaaaacuuuc uccaacggau gcgacuacgu uucaaacaaa     1320

gguguagaca cuguaucagu aggaaacaca cuauauuacg uaaauaaaca agaaggaaaa     1380

ucacuuuaug ucaaaggaga accaauaauc aauuucuacg acccauuagu auucccauca     1440

gacgaauuug augcuucaau aucacaagua aacgaaaaaa uaaaucaauc acucgcauuu     1500

auacgaaaau cagacgaacu acuacacaau guaaacgcag gcaaaucaac aacaaacaua     1560

augauaacaa caauaaucau uguaauaaua guaauacuuc uaucucuaau agcaguagga     1620

uuacuccucu acugcaaagc aagaucaacc ccuguaacac uaucaaaaga ccaacuuuca     1680

gguauaaaua auauagcuuu uuccaauuaa ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5622
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5622
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu aauccucaaa      120

gccaacgcga ucacuacaau ccucacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgagg aguucuacca aucaaccugc uccgccguau caaaaggaua ccuaagcgcc      240

cuacggaccg gcugguacac aucugucauc accaucgaac uaucaaacau caaagaaaac      300

aaaugcaacg gaaccgacgc aaaagucaaa cugauuaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaacugca auuacucaug caaagcacac cggccaccgg cucaggcagc      420

gccaucgccu ccggcgucgc cgucugcaaa guucuccacc ucgagggcga agucaacaaa      480

auaaaaucug cccuccucuc caccaacaaa gccgucgucu cccucagcgg cugcggaguc      540

uccguccuca ccuucaaagu ucucgaucuc aagaacuaua uugacaaaca acuucuaccc      600

auacucaaca aacaaagcug cagcauaucc aacaucgaaa ccgucaucga guuccaacaa      660

aagaacaacc gccuccucga aauaacccgc gaguucagcg uuaacgccgg agucacuacc      720

ccugucucca ccuacaugcu caccaacucc gaacuccuau cacuaaucaa cgacaugccc      780

auaaccaacg accagaagaa acucaugucc aacaacgucc aaauuguccg acaacaaagc      840

uacuccauaa ugugcauaau aaaagaggaa guccucgccu acgucguaca acugccccuu      900

uauggcguaa ucgacacacc cugcuggaaa cuccacacgu caccccucug caccaccaac      960

acaaaagaag gcucgaacau cugccuaaca cggacugacc gcggcuggua cugcgacaac     1020

gccggcuccg ucagcuucuu cccacaagcc gaaaccugca aaguacaauc caaccgagua     1080

uucugcgaca ccaugaacuc cagaacccuc cccucagagg ucaaccugug caacguagac     1140

aucuucaacc ccaaauacga cugcaaaaua augaccucaa aaacagacgu cuccucuucc     1200

guaaucacca gccucggagc caucgucagc ugcuacggca aaaccaaaug caccgccuca     1260

aacaaaugcc gcggcaucau caaaacauuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca caguaagcgu aggcaacaca cuguacuacg ucaacaaaca agagggaaaa     1380

ucacucuacg ucaaaggaga acccauaauc aacuucuacg acccccucgu uuuccccagc     1440

gacgaguucg acgccagcau aucccaaguc aacgagaaaa uuaaccaauc ccuagcauuc     1500

auccgaaaau cugacgaacu gcuccacaac gucaacgcgg gaaaaucaac aaccaacaua     1560

augauaacca caaucauaau agucaucauc guaauccucc ucagccuaau cgcugucggc     1620

cuccuccucu acugcaaagc ccguuccacc ccagucacac uuuccaagga ccaacuaagc     1680

ggaauaaaca acaucgcguu cucaaacuaa ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  5623
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5623
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5624
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5624
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccgguccacc ccggugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5625
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5625
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5626
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5626
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcucuaca ccggugaccc ugagcaagga ccagcucucc     1680

gggauaaaca auaucgcuuu cucaaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5627
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5627
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5628
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5628
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagauccaca ccugugaccc uuagcaagga ccagcucucu     1680

ggaauuaaca auaucgcguu cuccaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5629
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5629
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuuaaa      120

gccaacgcaa uaacaacaau ucucacugcu gucaccuucu gcuucgccuc aggccaaaac      180

auaacggaag aauuuuacca aucaacaugc ucugcaguau ccaaaggcua ccuaucugcu      240

cuaagaacag guugguauac aucaguaaua accauagaac uaucaaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguuaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguua ccgaacuaca acuacuuaug caauccacuc ccgccacugg aucaggauca      420

gcaauagcau caggagucgc aguauguaaa gucuuacacc ucgaaggcga agucaauaaa      480

aucaaauccg cauuacuauc cacaaacaaa gcagucguau cccuaagcgg augcggagua      540

ucaguacuaa cauuuaaagu acuagaccua aaaaauuaca ucgauaaaca acuauuaccu      600

auauuaaaca aacaauccug cuccauuuca aauaucgaaa ccguaauaga auuucaacaa      660

aaaaacaaca gauuacuaga aauaacaaga gaauuuuccg uaaaugcugg cguaacaaca      720

ccaguaucca cauacaugcu cacaaacucc gaacuacuau cacuaauaaa ugacaugccc      780

auaacaaacg aucaaaaaaa acuaauguca aauaauguac aaauaguaag acaacaaagc      840

uacuccauca uguguauaau aaaagaagaa guacuagcau acguaguuca acuaccacuu      900

uacggcguaa ucgacacccc uugcuggaaa cuacacaccu ccccucuaug caccacaaac      960

acaaaagaag guuccaacau augccuuacc agaacagaca gaggcuggua uugcgacaac     1020

gcaggaucag uuucauuuuu uccacaagcu gaaacaugca aaguacaauc aaacagaguc     1080

uucugcgaca caaugaacuc aagaacucua cccucagaag uaaaccuaug uaacguagac     1140

auuuucaacc ccaaauacga cugcaaaauu augacaucaa aaacagacgu uucaucauca     1200

guuaucaccu cauuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccuca     1260

aauaaaugca gaggaauaau aaaaacuuuc uccaacggau gcgacuacgu uucaaacaaa     1320

gguguagaca cuguaucagu aggaaacaca cuauauuacg uaaauaaaca agaaggaaaa     1380

ucacuuuaug ucaaaggaga accaauaauc aauuucuacg acccauuagu auucccauca     1440

gacgaauuug augcuucaau aucacaagua aacgaaaaaa uaaaucaauc acucgcauuu     1500

auacgaaaau cagacgaacu acuacacaau guaaacgcag gcaaaucaac aacaaacaua     1560

augauaacaa caauaaucau uguaauaaua guaauacuuc uaucucuaau agcaguagga     1620

uuacuccucu acugcaaagc aagaucaacc ccuguaacac uaucaaaaga ccaacuuuca     1680

gguauaaaua auauagcuuu uuccaauuaa ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5630
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5630
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu aauccucaaa      120

gccaacgcga ucacuacaau ccucacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgagg aguucuacca aucaaccugc uccgccguau caaaaggaua ccuaagcgcc      240

cuacggaccg gcugguacac aucugucauc accaucgaac uaucaaacau caaagaaaac      300

aaaugcaacg gaaccgacgc aaaagucaaa cugauuaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaacugca auuacucaug caaagcacac cggccaccgg cucaggcagc      420

gccaucgccu ccggcgucgc cgucugcaaa guucuccacc ucgagggcga agucaacaaa      480

auaaaaucug cccuccucuc caccaacaaa gccgucgucu cccucagcgg cugcggaguc      540

uccguccuca ccuucaaagu ucucgaucuc aagaacuaua uugacaaaca acuucuaccc      600

auacucaaca aacaaagcug cagcauaucc aacaucgaaa ccgucaucga guuccaacaa      660

aagaacaacc gccuccucga aauaacccgc gaguucagcg uuaacgccgg agucacuacc      720

ccugucucca ccuacaugcu caccaacucc gaacuccuau cacuaaucaa cgacaugccc      780

auaaccaacg accagaagaa acucaugucc aacaacgucc aaauuguccg acaacaaagc      840

uacuccauaa ugugcauaau aaaagaggaa guccucgccu acgucguaca acugccccuu      900

uauggcguaa ucgacacacc cugcuggaaa cuccacacgu caccccucug caccaccaac      960

acaaaagaag gcucgaacau cugccuaaca cggacugacc gcggcuggua cugcgacaac     1020

gccggcuccg ucagcuucuu cccacaagcc gaaaccugca aaguacaauc caaccgagua     1080

uucugcgaca ccaugaacuc cagaacccuc cccucagagg ucaaccugug caacguagac     1140

aucuucaacc ccaaauacga cugcaaaaua augaccucaa aaacagacgu cuccucuucc     1200

guaaucacca gccucggagc caucgucagc ugcuacggca aaaccaaaug caccgccuca     1260

aacaaaugcc gcggcaucau caaaacauuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca caguaagcgu aggcaacaca cuguacuacg ucaacaaaca agagggaaaa     1380

ucacucuacg ucaaaggaga acccauaauc aacuucuacg acccccucgu uuuccccagc     1440

gacgaguucg acgccagcau aucccaaguc aacgagaaaa uuaaccaauc ccuagcauuc     1500

auccgaaaau cugacgaacu gcuccacaac gucaacgcgg gaaaaucaac aaccaacaua     1560

augauaacca caaucauaau agucaucauc guaauccucc ucagccuaau cgcugucggc     1620

cuccuccucu acugcaaagc ccguuccacc ccagucacac uuuccaagga ccaacuaagc     1680

ggaauaaaca acaucgcguu cucaaacuaa ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  5631
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5631
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5632
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5632
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccgguccacc ccggugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5633
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5633
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5634
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5634
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcucuaca ccggugaccc ugagcaagga ccagcucucc     1680

gggauaaaca auaucgcuuu cucaaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5635
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5635
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5636
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5636
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagauccaca ccugugaccc uuagcaagga ccagcucucu     1680

ggaauuaaca auaucgcguu cuccaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5637
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5637
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuuaaa      120

gccaacgcaa uaacaacaau ucucacugcu gucaccuucu gcuucgccuc aggccaaaac      180

auaacggaag aauuuuacca aucaacaugc ucugcaguau ccaaaggcua ccuaucugcu      240

cuaagaacag guugguauac aucaguaaua accauagaac uaucaaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguuaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguua ccgaacuaca acuacuuaug caauccacuc ccgccacugg aucaggauca      420

gcaauagcau caggagucgc aguauguaaa gucuuacacc ucgaaggcga agucaauaaa      480

aucaaauccg cauuacuauc cacaaacaaa gcagucguau cccuaagcgg augcggagua      540

ucaguacuaa cauuuaaagu acuagaccua aaaaauuaca ucgauaaaca acuauuaccu      600

auauuaaaca aacaauccug cuccauuuca aauaucgaaa ccguaauaga auuucaacaa      660

aaaaacaaca gauuacuaga aauaacaaga gaauuuuccg uaaaugcugg cguaacaaca      720

ccaguaucca cauacaugcu cacaaacucc gaacuacuau cacuaauaaa ugacaugccc      780

auaacaaacg aucaaaaaaa acuaauguca aauaauguac aaauaguaag acaacaaagc      840

uacuccauca uguguauaau aaaagaagaa guacuagcau acguaguuca acuaccacuu      900

uacggcguaa ucgacacccc uugcuggaaa cuacacaccu ccccucuaug caccacaaac      960

acaaaagaag guuccaacau augccuuacc agaacagaca gaggcuggua uugcgacaac     1020

gcaggaucag uuucauuuuu uccacaagcu gaaacaugca aaguacaauc aaacagaguc     1080

uucugcgaca caaugaacuc aagaacucua cccucagaag uaaaccuaug uaacguagac     1140

auuuucaacc ccaaauacga cugcaaaauu augacaucaa aaacagacgu uucaucauca     1200

guuaucaccu cauuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccuca     1260

aauaaaugca gaggaauaau aaaaacuuuc uccaacggau gcgacuacgu uucaaacaaa     1320

gguguagaca cuguaucagu aggaaacaca cuauauuacg uaaauaaaca agaaggaaaa     1380

ucacuuuaug ucaaaggaga accaauaauc aauuucuacg acccauuagu auucccauca     1440

gacgaauuug augcuucaau aucacaagua aacgaaaaaa uaaaucaauc acucgcauuu     1500

auacgaaaau cagacgaacu acuacacaau guaaacgcag gcaaaucaac aacaaacaua     1560

augauaacaa caauaaucau uguaauaaua guaauacuuc uaucucuaau agcaguagga     1620

uuacuccucu acugcaaagc aagaucaacc ccuguaacac uaucaaaaga ccaacuuuca     1680

gguauaaaua auauagcuuu uuccaauuaa ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5638
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5638
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu aauccucaaa      120

gccaacgcga ucacuacaau ccucacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgagg aguucuacca aucaaccugc uccgccguau caaaaggaua ccuaagcgcc      240

cuacggaccg gcugguacac aucugucauc accaucgaac uaucaaacau caaagaaaac      300

aaaugcaacg gaaccgacgc aaaagucaaa cugauuaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaacugca auuacucaug caaagcacac cggccaccgg cucaggcagc      420

gccaucgccu ccggcgucgc cgucugcaaa guucuccacc ucgagggcga agucaacaaa      480

auaaaaucug cccuccucuc caccaacaaa gccgucgucu cccucagcgg cugcggaguc      540

uccguccuca ccuucaaagu ucucgaucuc aagaacuaua uugacaaaca acuucuaccc      600

auacucaaca aacaaagcug cagcauaucc aacaucgaaa ccgucaucga guuccaacaa      660

aagaacaacc gccuccucga aauaacccgc gaguucagcg uuaacgccgg agucacuacc      720

ccugucucca ccuacaugcu caccaacucc gaacuccuau cacuaaucaa cgacaugccc      780

auaaccaacg accagaagaa acucaugucc aacaacgucc aaauuguccg acaacaaagc      840

uacuccauaa ugugcauaau aaaagaggaa guccucgccu acgucguaca acugccccuu      900

uauggcguaa ucgacacacc cugcuggaaa cuccacacgu caccccucug caccaccaac      960

acaaaagaag gcucgaacau cugccuaaca cggacugacc gcggcuggua cugcgacaac     1020

gccggcuccg ucagcuucuu cccacaagcc gaaaccugca aaguacaauc caaccgagua     1080

uucugcgaca ccaugaacuc cagaacccuc cccucagagg ucaaccugug caacguagac     1140

aucuucaacc ccaaauacga cugcaaaaua augaccucaa aaacagacgu cuccucuucc     1200

guaaucacca gccucggagc caucgucagc ugcuacggca aaaccaaaug caccgccuca     1260

aacaaaugcc gcggcaucau caaaacauuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca caguaagcgu aggcaacaca cuguacuacg ucaacaaaca agagggaaaa     1380

ucacucuacg ucaaaggaga acccauaauc aacuucuacg acccccucgu uuuccccagc     1440

gacgaguucg acgccagcau aucccaaguc aacgagaaaa uuaaccaauc ccuagcauuc     1500

auccgaaaau cugacgaacu gcuccacaac gucaacgcgg gaaaaucaac aaccaacaua     1560

augauaacca caaucauaau agucaucauc guaauccucc ucagccuaau cgcugucggc     1620

cuccuccucu acugcaaagc ccguuccacc ccagucacac uuuccaagga ccaacuaagc     1680

ggaauaaaca acaucgcguu cucaaacuaa ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  5639
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5639
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5640
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5640
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccgguccacc ccggugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5641
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5641
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5642
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5642
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcucuaca ccggugaccc ugagcaagga ccagcucucc     1680

gggauaaaca auaucgcuuu cucaaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5643
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5643
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5644
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5644
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagauccaca ccugugaccc uuagcaagga ccagcucucu     1680

ggaauuaaca auaucgcguu cuccaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5645
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5645
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauacuuaaa      120

gccaacgcaa uaacaacaau ucucacugcu gucaccuucu gcuucgccuc aggccaaaac      180

auaacggaag aauuuuacca aucaacaugc ucugcaguau ccaaaggcua ccuaucugcu      240

cuaagaacag guugguauac aucaguaaua accauagaac uaucaaacau aaaagaaaau      300

aaaugcaacg gaacagacgc aaaaguuaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguua ccgaacuaca acuacuuaug caauccacuc ccgccacugg aucaggauca      420

gcaauagcau caggagucgc aguauguaaa gucuuacacc ucgaaggcga agucaauaaa      480

aucaaauccg cauuacuauc cacaaacaaa gcagucguau cccuaagcgg augcggagua      540

ucaguacuaa cauuuaaagu acuagaccua aaaaauuaca ucgauaaaca acuauuaccu      600

auauuaaaca aacaauccug cuccauuuca aauaucgaaa ccguaauaga auuucaacaa      660

aaaaacaaca gauuacuaga aauaacaaga gaauuuuccg uaaaugcugg cguaacaaca      720

ccaguaucca cauacaugcu cacaaacucc gaacuacuau cacuaauaaa ugacaugccc      780

auaacaaacg aucaaaaaaa acuaauguca aauaauguac aaauaguaag acaacaaagc      840

uacuccauca uguguauaau aaaagaagaa guacuagcau acguaguuca acuaccacuu      900

uacggcguaa ucgacacccc uugcuggaaa cuacacaccu ccccucuaug caccacaaac      960

acaaaagaag guuccaacau augccuuacc agaacagaca gaggcuggua uugcgacaac     1020

gcaggaucag uuucauuuuu uccacaagcu gaaacaugca aaguacaauc aaacagaguc     1080

uucugcgaca caaugaacuc aagaacucua cccucagaag uaaaccuaug uaacguagac     1140

auuuucaacc ccaaauacga cugcaaaauu augacaucaa aaacagacgu uucaucauca     1200

guuaucaccu cauuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccuca     1260

aauaaaugca gaggaauaau aaaaacuuuc uccaacggau gcgacuacgu uucaaacaaa     1320

gguguagaca cuguaucagu aggaaacaca cuauauuacg uaaauaaaca agaaggaaaa     1380

ucacuuuaug ucaaaggaga accaauaauc aauuucuacg acccauuagu auucccauca     1440

gacgaauuug augcuucaau aucacaagua aacgaaaaaa uaaaucaauc acucgcauuu     1500

auacgaaaau cagacgaacu acuacacaau guaaacgcag gcaaaucaac aacaaacaua     1560

augauaacaa caauaaucau uguaauaaua guaauacuuc uaucucuaau agcaguagga     1620

uuacuccucu acugcaaagc aagaucaacc ccuguaacac uaucaaaaga ccaacuuuca     1680

gguauaaaua auauagcuuu uuccaauuaa ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5646
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5646
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu aauccucaaa      120

gccaacgcga ucacuacaau ccucacagcc gucaccuucu gcuucgccuc cggccaaaac      180

aucaccgagg aguucuacca aucaaccugc uccgccguau caaaaggaua ccuaagcgcc      240

cuacggaccg gcugguacac aucugucauc accaucgaac uaucaaacau caaagaaaac      300

aaaugcaacg gaaccgacgc aaaagucaaa cugauuaaac aagaacuaga caaauacaaa      360

aacgcaguca ccgaacugca auuacucaug caaagcacac cggccaccgg cucaggcagc      420

gccaucgccu ccggcgucgc cgucugcaaa guucuccacc ucgagggcga agucaacaaa      480

auaaaaucug cccuccucuc caccaacaaa gccgucgucu cccucagcgg cugcggaguc      540

uccguccuca ccuucaaagu ucucgaucuc aagaacuaua uugacaaaca acuucuaccc      600

auacucaaca aacaaagcug cagcauaucc aacaucgaaa ccgucaucga guuccaacaa      660

aagaacaacc gccuccucga aauaacccgc gaguucagcg uuaacgccgg agucacuacc      720

ccugucucca ccuacaugcu caccaacucc gaacuccuau cacuaaucaa cgacaugccc      780

auaaccaacg accagaagaa acucaugucc aacaacgucc aaauuguccg acaacaaagc      840

uacuccauaa ugugcauaau aaaagaggaa guccucgccu acgucguaca acugccccuu      900

uauggcguaa ucgacacacc cugcuggaaa cuccacacgu caccccucug caccaccaac      960

acaaaagaag gcucgaacau cugccuaaca cggacugacc gcggcuggua cugcgacaac     1020

gccggcuccg ucagcuucuu cccacaagcc gaaaccugca aaguacaauc caaccgagua     1080

uucugcgaca ccaugaacuc cagaacccuc cccucagagg ucaaccugug caacguagac     1140

aucuucaacc ccaaauacga cugcaaaaua augaccucaa aaacagacgu cuccucuucc     1200

guaaucacca gccucggagc caucgucagc ugcuacggca aaaccaaaug caccgccuca     1260

aacaaaugcc gcggcaucau caaaacauuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca caguaagcgu aggcaacaca cuguacuacg ucaacaaaca agagggaaaa     1380

ucacucuacg ucaaaggaga acccauaauc aacuucuacg acccccucgu uuuccccagc     1440

gacgaguucg acgccagcau aucccaaguc aacgagaaaa uuaaccaauc ccuagcauuc     1500

auccgaaaau cugacgaacu gcuccacaac gucaacgcgg gaaaaucaac aaccaacaua     1560

augauaacca caaucauaau agucaucauc guaauccucc ucagccuaau cgcugucggc     1620

cuccuccucu acugcaaagc ccguuccacc ccagucacac uuuccaagga ccaacuaagc     1680

ggaauaaaca acaucgcguu cucaaacuaa ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  5647
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5647
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5648
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5648
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5649
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5649
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5650
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5650
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1740

aaggaccagc ucuccgggau aaacaauauc gcuuucucaa acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5651
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5651
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5652
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5652
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1740

aaggaccagc ucucuggaau uaacaauauc gcguucucca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5653
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5653
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uuaaagccaa cgcaauaaca acaauucuca cugcugucac cuucugcuuc      240

gccucaggcc aaaacauaac ggaagaauuu uaccaaucaa caugcucugc aguauccaaa      300

ggcuaccuau cugcucuaag aacagguugg uauacaucag uaauaaccau agaacuauca      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uuaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguuaccgaa cuacaacuac uuaugcaauc cacucccgcc      480

acuggaucag gaucagcaau agcaucagga gucgcaguau guaaagucuu acaccucgaa      540

ggcgaaguca auaaaaucaa auccgcauua cuauccacaa acaaagcagu cguaucccua      600

agcggaugcg gaguaucagu acuaacauuu aaaguacuag accuaaaaaa uuacaucgau      660

aaacaacuau uaccuauauu aaacaaacaa uccugcucca uuucaaauau cgaaaccgua      720

auagaauuuc aacaaaaaaa caacagauua cuagaaauaa caagagaauu uuccguaaau      780

gcuggcguaa caacaccagu auccacauac augcucacaa acuccgaacu acuaucacua      840

auaaaugaca ugcccauaac aaacgaucaa aaaaaacuaa ugucaaauaa uguacaaaua      900

guaagacaac aaagcuacuc caucaugugu auaauaaaag aagaaguacu agcauacgua      960

guucaacuac cacuuuacgg cguaaucgac accccuugcu ggaaacuaca caccuccccu     1020

cuaugcacca caaacacaaa agaagguucc aacauaugcc uuaccagaac agacagaggc     1080

ugguauugcg acaacgcagg aucaguuuca uuuuuuccac aagcugaaac augcaaagua     1140

caaucaaaca gagucuucug cgacacaaug aacucaagaa cucuacccuc agaaguaaac     1200

cuauguaacg uagacauuuu caaccccaaa uacgacugca aaauuaugac aucaaaaaca     1260

gacguuucau caucaguuau caccucauua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucaaauaa augcagagga auaauaaaaa cuuucuccaa cggaugcgac     1380

uacguuucaa acaaaggugu agacacugua ucaguaggaa acacacuaua uuacguaaau     1440

aaacaagaag gaaaaucacu uuaugucaaa ggagaaccaa uaaucaauuu cuacgaccca     1500

uuaguauucc caucagacga auuugaugcu ucaauaucac aaguaaacga aaaaauaaau     1560

caaucacucg cauuuauacg aaaaucagac gaacuacuac acaauguaaa cgcaggcaaa     1620

ucaacaacaa acauaaugau aacaacaaua aucauuguaa uaauaguaau acuucuaucu     1680

cuaauagcag uaggauuacu ccucuacugc aaagcaagau caaccccugu aacacuauca     1740

aaagaccaac uuucagguau aaauaauaua gcuuuuucca auuaaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5654
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5654
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccuaaucc ucaaagccaa cgcgaucacu acaauccuca cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaggaguuc uaccaaucaa ccugcuccgc cguaucaaaa      300

ggauaccuaa gcgcccuacg gaccggcugg uacacaucug ucaucaccau cgaacuauca      360

aacaucaaag aaaacaaaug caacggaacc gacgcaaaag ucaaacugau uaaacaagaa      420

cuagacaaau acaaaaacgc agucaccgaa cugcaauuac ucaugcaaag cacaccggcc      480

accggcucag gcagcgccau cgccuccggc gucgccgucu gcaaaguucu ccaccucgag      540

ggcgaaguca acaaaauaaa aucugcccuc cucuccacca acaaagccgu cgucucccuc      600

agcggcugcg gagucuccgu ccucaccuuc aaaguucucg aucucaagaa cuauauugac      660

aaacaacuuc uacccauacu caacaaacaa agcugcagca uauccaacau cgaaaccguc      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauaa cccgcgaguu cagcguuaac      780

gccggaguca cuaccccugu cuccaccuac augcucacca acuccgaacu ccuaucacua      840

aucaacgaca ugcccauaac caacgaccag aagaaacuca uguccaacaa cguccaaauu      900

guccgacaac aaagcuacuc cauaaugugc auaauaaaag aggaaguccu cgccuacguc      960

guacaacugc cccuuuaugg cguaaucgac acacccugcu ggaaacucca cacgucaccc     1020

cucugcacca ccaacacaaa agaaggcucg aacaucugcc uaacacggac ugaccgcggc     1080

ugguacugcg acaacgccgg cuccgucagc uucuucccac aagccgaaac cugcaaagua     1140

caauccaacc gaguauucug cgacaccaug aacuccagaa cccuccccuc agaggucaac     1200

cugugcaacg uagacaucuu caaccccaaa uacgacugca aaauaaugac cucaaaaaca     1260

gacgucuccu cuuccguaau caccagccuc ggagccaucg ucagcugcua cggcaaaacc     1320

aaaugcaccg ccucaaacaa augccgcggc aucaucaaaa cauucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacacagua agcguaggca acacacugua cuacgucaac     1440

aaacaagagg gaaaaucacu cuacgucaaa ggagaaccca uaaucaacuu cuacgacccc     1500

cucguuuucc ccagcgacga guucgacgcc agcauauccc aagucaacga gaaaauuaac     1560

caaucccuag cauucauccg aaaaucugac gaacugcucc acaacgucaa cgcgggaaaa     1620

ucaacaacca acauaaugau aaccacaauc auaauaguca ucaucguaau ccuccucagc     1680

cuaaucgcug ucggccuccu ccucuacugc aaagcccguu ccaccccagu cacacuuucc     1740

aaggaccaac uaagcggaau aaacaacauc gcguucucaa acuaaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  5655
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5655
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5656
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5656
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5657
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5657
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5658
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5658
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1740

aaggaccagc ucuccgggau aaacaauauc gcuuucucaa acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5659
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5659
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5660
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5660
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1740

aaggaccagc ucucuggaau uaacaauauc gcguucucca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5661
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5661
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uuaaagccaa cgcaauaaca acaauucuca cugcugucac cuucugcuuc      240

gccucaggcc aaaacauaac ggaagaauuu uaccaaucaa caugcucugc aguauccaaa      300

ggcuaccuau cugcucuaag aacagguugg uauacaucag uaauaaccau agaacuauca      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uuaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguuaccgaa cuacaacuac uuaugcaauc cacucccgcc      480

acuggaucag gaucagcaau agcaucagga gucgcaguau guaaagucuu acaccucgaa      540

ggcgaaguca auaaaaucaa auccgcauua cuauccacaa acaaagcagu cguaucccua      600

agcggaugcg gaguaucagu acuaacauuu aaaguacuag accuaaaaaa uuacaucgau      660

aaacaacuau uaccuauauu aaacaaacaa uccugcucca uuucaaauau cgaaaccgua      720

auagaauuuc aacaaaaaaa caacagauua cuagaaauaa caagagaauu uuccguaaau      780

gcuggcguaa caacaccagu auccacauac augcucacaa acuccgaacu acuaucacua      840

auaaaugaca ugcccauaac aaacgaucaa aaaaaacuaa ugucaaauaa uguacaaaua      900

guaagacaac aaagcuacuc caucaugugu auaauaaaag aagaaguacu agcauacgua      960

guucaacuac cacuuuacgg cguaaucgac accccuugcu ggaaacuaca caccuccccu     1020

cuaugcacca caaacacaaa agaagguucc aacauaugcc uuaccagaac agacagaggc     1080

ugguauugcg acaacgcagg aucaguuuca uuuuuuccac aagcugaaac augcaaagua     1140

caaucaaaca gagucuucug cgacacaaug aacucaagaa cucuacccuc agaaguaaac     1200

cuauguaacg uagacauuuu caaccccaaa uacgacugca aaauuaugac aucaaaaaca     1260

gacguuucau caucaguuau caccucauua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucaaauaa augcagagga auaauaaaaa cuuucuccaa cggaugcgac     1380

uacguuucaa acaaaggugu agacacugua ucaguaggaa acacacuaua uuacguaaau     1440

aaacaagaag gaaaaucacu uuaugucaaa ggagaaccaa uaaucaauuu cuacgaccca     1500

uuaguauucc caucagacga auuugaugcu ucaauaucac aaguaaacga aaaaauaaau     1560

caaucacucg cauuuauacg aaaaucagac gaacuacuac acaauguaaa cgcaggcaaa     1620

ucaacaacaa acauaaugau aacaacaaua aucauuguaa uaauaguaau acuucuaucu     1680

cuaauagcag uaggauuacu ccucuacugc aaagcaagau caaccccugu aacacuauca     1740

aaagaccaac uuucagguau aaauaauaua gcuuuuucca auuaaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5662
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5662
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccuaaucc ucaaagccaa cgcgaucacu acaauccuca cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaggaguuc uaccaaucaa ccugcuccgc cguaucaaaa      300

ggauaccuaa gcgcccuacg gaccggcugg uacacaucug ucaucaccau cgaacuauca      360

aacaucaaag aaaacaaaug caacggaacc gacgcaaaag ucaaacugau uaaacaagaa      420

cuagacaaau acaaaaacgc agucaccgaa cugcaauuac ucaugcaaag cacaccggcc      480

accggcucag gcagcgccau cgccuccggc gucgccgucu gcaaaguucu ccaccucgag      540

ggcgaaguca acaaaauaaa aucugcccuc cucuccacca acaaagccgu cgucucccuc      600

agcggcugcg gagucuccgu ccucaccuuc aaaguucucg aucucaagaa cuauauugac      660

aaacaacuuc uacccauacu caacaaacaa agcugcagca uauccaacau cgaaaccguc      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauaa cccgcgaguu cagcguuaac      780

gccggaguca cuaccccugu cuccaccuac augcucacca acuccgaacu ccuaucacua      840

aucaacgaca ugcccauaac caacgaccag aagaaacuca uguccaacaa cguccaaauu      900

guccgacaac aaagcuacuc cauaaugugc auaauaaaag aggaaguccu cgccuacguc      960

guacaacugc cccuuuaugg cguaaucgac acacccugcu ggaaacucca cacgucaccc     1020

cucugcacca ccaacacaaa agaaggcucg aacaucugcc uaacacggac ugaccgcggc     1080

ugguacugcg acaacgccgg cuccgucagc uucuucccac aagccgaaac cugcaaagua     1140

caauccaacc gaguauucug cgacaccaug aacuccagaa cccuccccuc agaggucaac     1200

cugugcaacg uagacaucuu caaccccaaa uacgacugca aaauaaugac cucaaaaaca     1260

gacgucuccu cuuccguaau caccagccuc ggagccaucg ucagcugcua cggcaaaacc     1320

aaaugcaccg ccucaaacaa augccgcggc aucaucaaaa cauucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacacagua agcguaggca acacacugua cuacgucaac     1440

aaacaagagg gaaaaucacu cuacgucaaa ggagaaccca uaaucaacuu cuacgacccc     1500

cucguuuucc ccagcgacga guucgacgcc agcauauccc aagucaacga gaaaauuaac     1560

caaucccuag cauucauccg aaaaucugac gaacugcucc acaacgucaa cgcgggaaaa     1620

ucaacaacca acauaaugau aaccacaauc auaauaguca ucaucguaau ccuccucagc     1680

cuaaucgcug ucggccuccu ccucuacugc aaagcccguu ccaccccagu cacacuuucc     1740

aaggaccaac uaagcggaau aaacaacauc gcguucucaa acuaaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  5663
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5663
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5664
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5664
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu ccaccccggu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5665
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5665
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5666
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5666
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu cuacaccggu gacccugagc     1740

aaggaccagc ucuccgggau aaacaauauc gcuuucucaa acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5667
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5667
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5668
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5668
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau ccacaccugu gacccuuagc     1740

aaggaccagc ucucuggaau uaacaauauc gcguucucca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5669
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5669
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauac uuaaagccaa cgcaauaaca acaauucuca cugcugucac cuucugcuuc      240

gccucaggcc aaaacauaac ggaagaauuu uaccaaucaa caugcucugc aguauccaaa      300

ggcuaccuau cugcucuaag aacagguugg uauacaucag uaauaaccau agaacuauca      360

aacauaaaag aaaauaaaug caacggaaca gacgcaaaag uuaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguuaccgaa cuacaacuac uuaugcaauc cacucccgcc      480

acuggaucag gaucagcaau agcaucagga gucgcaguau guaaagucuu acaccucgaa      540

ggcgaaguca auaaaaucaa auccgcauua cuauccacaa acaaagcagu cguaucccua      600

agcggaugcg gaguaucagu acuaacauuu aaaguacuag accuaaaaaa uuacaucgau      660

aaacaacuau uaccuauauu aaacaaacaa uccugcucca uuucaaauau cgaaaccgua      720

auagaauuuc aacaaaaaaa caacagauua cuagaaauaa caagagaauu uuccguaaau      780

gcuggcguaa caacaccagu auccacauac augcucacaa acuccgaacu acuaucacua      840

auaaaugaca ugcccauaac aaacgaucaa aaaaaacuaa ugucaaauaa uguacaaaua      900

guaagacaac aaagcuacuc caucaugugu auaauaaaag aagaaguacu agcauacgua      960

guucaacuac cacuuuacgg cguaaucgac accccuugcu ggaaacuaca caccuccccu     1020

cuaugcacca caaacacaaa agaagguucc aacauaugcc uuaccagaac agacagaggc     1080

ugguauugcg acaacgcagg aucaguuuca uuuuuuccac aagcugaaac augcaaagua     1140

caaucaaaca gagucuucug cgacacaaug aacucaagaa cucuacccuc agaaguaaac     1200

cuauguaacg uagacauuuu caaccccaaa uacgacugca aaauuaugac aucaaaaaca     1260

gacguuucau caucaguuau caccucauua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucaaauaa augcagagga auaauaaaaa cuuucuccaa cggaugcgac     1380

uacguuucaa acaaaggugu agacacugua ucaguaggaa acacacuaua uuacguaaau     1440

aaacaagaag gaaaaucacu uuaugucaaa ggagaaccaa uaaucaauuu cuacgaccca     1500

uuaguauucc caucagacga auuugaugcu ucaauaucac aaguaaacga aaaaauaaau     1560

caaucacucg cauuuauacg aaaaucagac gaacuacuac acaauguaaa cgcaggcaaa     1620

ucaacaacaa acauaaugau aacaacaaua aucauuguaa uaauaguaau acuucuaucu     1680

cuaauagcag uaggauuacu ccucuacugc aaagcaagau caaccccugu aacacuauca     1740

aaagaccaac uuucagguau aaauaauaua gcuuuuucca auuaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5670
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5670
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccuaaucc ucaaagccaa cgcgaucacu acaauccuca cagccgucac cuucugcuuc      240

gccuccggcc aaaacaucac cgaggaguuc uaccaaucaa ccugcuccgc cguaucaaaa      300

ggauaccuaa gcgcccuacg gaccggcugg uacacaucug ucaucaccau cgaacuauca      360

aacaucaaag aaaacaaaug caacggaacc gacgcaaaag ucaaacugau uaaacaagaa      420

cuagacaaau acaaaaacgc agucaccgaa cugcaauuac ucaugcaaag cacaccggcc      480

accggcucag gcagcgccau cgccuccggc gucgccgucu gcaaaguucu ccaccucgag      540

ggcgaaguca acaaaauaaa aucugcccuc cucuccacca acaaagccgu cgucucccuc      600

agcggcugcg gagucuccgu ccucaccuuc aaaguucucg aucucaagaa cuauauugac      660

aaacaacuuc uacccauacu caacaaacaa agcugcagca uauccaacau cgaaaccguc      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauaa cccgcgaguu cagcguuaac      780

gccggaguca cuaccccugu cuccaccuac augcucacca acuccgaacu ccuaucacua      840

aucaacgaca ugcccauaac caacgaccag aagaaacuca uguccaacaa cguccaaauu      900

guccgacaac aaagcuacuc cauaaugugc auaauaaaag aggaaguccu cgccuacguc      960

guacaacugc cccuuuaugg cguaaucgac acacccugcu ggaaacucca cacgucaccc     1020

cucugcacca ccaacacaaa agaaggcucg aacaucugcc uaacacggac ugaccgcggc     1080

ugguacugcg acaacgccgg cuccgucagc uucuucccac aagccgaaac cugcaaagua     1140

caauccaacc gaguauucug cgacaccaug aacuccagaa cccuccccuc agaggucaac     1200

cugugcaacg uagacaucuu caaccccaaa uacgacugca aaauaaugac cucaaaaaca     1260

gacgucuccu cuuccguaau caccagccuc ggagccaucg ucagcugcua cggcaaaacc     1320

aaaugcaccg ccucaaacaa augccgcggc aucaucaaaa cauucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacacagua agcguaggca acacacugua cuacgucaac     1440

aaacaagagg gaaaaucacu cuacgucaaa ggagaaccca uaaucaacuu cuacgacccc     1500

cucguuuucc ccagcgacga guucgacgcc agcauauccc aagucaacga gaaaauuaac     1560

caaucccuag cauucauccg aaaaucugac gaacugcucc acaacgucaa cgcgggaaaa     1620

ucaacaacca acauaaugau aaccacaauc auaauaguca ucaucguaau ccuccucagc     1680

cuaaucgcug ucggccuccu ccucuacugc aaagcccguu ccaccccagu cacacuuucc     1740

aaggaccaac uaagcggaau aaacaacauc gcguucucaa acuaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5671
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5671
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1620

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5672
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5672
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1080

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1200

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccguggggcu ccugcuguac ugcaaggccc gguccacccc ggugacccug     1620

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5673
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5673
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1620

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5674
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5674
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      540

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      600

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      660

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      720

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      780

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau      840

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc      900

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu      960

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1020

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1080

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1140

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1200

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1260

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1320

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1440

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1500

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1560

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcucuacacc ggugacccug     1620

agcaaggacc agcucuccgg gauaaacaau aucgcuuucu caaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5675
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5675
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1620

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5676
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5676
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      540

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      600

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      660

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      720

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      780

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau      840

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu      900

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc      960

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1020

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1080

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1140

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1200

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1260

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1320

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1440

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1500

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1560

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gauccacacc ugugacccuu     1620

agcaaggacc agcucucugg aauuaacaau aucgcguucu ccaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5677
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5677
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuauuaa uacuuaaagc caacgcaaua acaacaauuc ucacugcugu caccuucugc      120

uucgccucag gccaaaacau aacggaagaa uuuuaccaau caacaugcuc ugcaguaucc      180

aaaggcuacc uaucugcucu aagaacaggu ugguauacau caguaauaac cauagaacua      240

ucaaacauaa aagaaaauaa augcaacgga acagacgcaa aaguuaaacu cauaaaacaa      300

gaacuagaca aauauaaaaa cgcaguuacc gaacuacaac uacuuaugca auccacuccc      360

gccacuggau caggaucagc aauagcauca ggagucgcag uauguaaagu cuuacaccuc      420

gaaggcgaag ucaauaaaau caaauccgca uuacuaucca caaacaaagc agucguaucc      480

cuaagcggau gcggaguauc aguacuaaca uuuaaaguac uagaccuaaa aaauuacauc      540

gauaaacaac uauuaccuau auuaaacaaa caauccugcu ccauuucaaa uaucgaaacc      600

guaauagaau uucaacaaaa aaacaacaga uuacuagaaa uaacaagaga auuuuccgua      660

aaugcuggcg uaacaacacc aguauccaca uacaugcuca caaacuccga acuacuauca      720

cuaauaaaug acaugcccau aacaaacgau caaaaaaaac uaaugucaaa uaauguacaa      780

auaguaagac aacaaagcua cuccaucaug uguauaauaa aagaagaagu acuagcauac      840

guaguucaac uaccacuuua cggcguaauc gacaccccuu gcuggaaacu acacaccucc      900

ccucuaugca ccacaaacac aaaagaaggu uccaacauau gccuuaccag aacagacaga      960

ggcugguauu gcgacaacgc aggaucaguu ucauuuuuuc cacaagcuga aacaugcaaa     1020

guacaaucaa acagagucuu cugcgacaca augaacucaa gaacucuacc cucagaagua     1080

aaccuaugua acguagacau uuucaacccc aaauacgacu gcaaaauuau gacaucaaaa     1140

acagacguuu caucaucagu uaucaccuca uuaggagcaa uaguaagcug cuacggaaaa     1200

acaaaaugca ccgccucaaa uaaaugcaga ggaauaauaa aaacuuucuc caacggaugc     1260

gacuacguuu caaacaaagg uguagacacu guaucaguag gaaacacacu auauuacgua     1320

aauaaacaag aaggaaaauc acuuuauguc aaaggagaac caauaaucaa uuucuacgac     1380

ccauuaguau ucccaucaga cgaauuugau gcuucaauau cacaaguaaa cgaaaaaaua     1440

aaucaaucac ucgcauuuau acgaaaauca gacgaacuac uacacaaugu aaacgcaggc     1500

aaaucaacaa caaacauaau gauaacaaca auaaucauug uaauaauagu aauacuucua     1560

ucucuaauag caguaggauu acuccucuac ugcaaagcaa gaucaacccc uguaacacua     1620

ucaaaagacc aacuuucagg uauaaauaau auagcuuuuu ccaauuaagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5678
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5678
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuaa uccucaaagc caacgcgauc acuacaaucc ucacagccgu caccuucugc      120

uucgccuccg gccaaaacau caccgaggag uucuaccaau caaccugcuc cgccguauca      180

aaaggauacc uaagcgcccu acggaccggc ugguacacau cugucaucac caucgaacua      240

ucaaacauca aagaaaacaa augcaacgga accgacgcaa aagucaaacu gauuaaacaa      300

gaacuagaca aauacaaaaa cgcagucacc gaacugcaau uacucaugca aagcacaccg      360

gccaccggcu caggcagcgc caucgccucc ggcgucgccg ucugcaaagu ucuccaccuc      420

gagggcgaag ucaacaaaau aaaaucugcc cuccucucca ccaacaaagc cgucgucucc      480

cucagcggcu gcggagucuc cguccucacc uucaaaguuc ucgaucucaa gaacuauauu      540

gacaaacaac uucuacccau acucaacaaa caaagcugca gcauauccaa caucgaaacc      600

gucaucgagu uccaacaaaa gaacaaccgc cuccucgaaa uaacccgcga guucagcguu      660

aacgccggag ucacuacccc ugucuccacc uacaugcuca ccaacuccga acuccuauca      720

cuaaucaacg acaugcccau aaccaacgac cagaagaaac ucauguccaa caacguccaa      780

auuguccgac aacaaagcua cuccauaaug ugcauaauaa aagaggaagu ccucgccuac      840

gucguacaac ugccccuuua uggcguaauc gacacacccu gcuggaaacu ccacacguca      900

ccccucugca ccaccaacac aaaagaaggc ucgaacaucu gccuaacacg gacugaccgc      960

ggcugguacu gcgacaacgc cggcuccguc agcuucuucc cacaagccga aaccugcaaa     1020

guacaaucca accgaguauu cugcgacacc augaacucca gaacccuccc cucagagguc     1080

aaccugugca acguagacau cuucaacccc aaauacgacu gcaaaauaau gaccucaaaa     1140

acagacgucu ccucuuccgu aaucaccagc cucggagcca ucgucagcug cuacggcaaa     1200

accaaaugca ccgccucaaa caaaugccgc ggcaucauca aaacauucuc aaacggcugc     1260

gacuacgucu ccaacaaagg cgucgacaca guaagcguag gcaacacacu guacuacguc     1320

aacaaacaag agggaaaauc acucuacguc aaaggagaac ccauaaucaa cuucuacgac     1380

ccccucguuu uccccagcga cgaguucgac gccagcauau cccaagucaa cgagaaaauu     1440

aaccaauccc uagcauucau ccgaaaaucu gacgaacugc uccacaacgu caacgcggga     1500

aaaucaacaa ccaacauaau gauaaccaca aucauaauag ucaucaucgu aauccuccuc     1560

agccuaaucg cugucggccu ccuccucuac ugcaaagccc guuccacccc agucacacuu     1620

uccaaggacc aacuaagcgg aauaaacaac aucgcguucu caaacuaagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5679
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5679
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc gagacgguga      600

ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc agcgugaacg      660

ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc cugucccuga      720

ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gcguacgugg      840

uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac acgagccccc      900

ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc gaccggggcu      960

gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc ugcaaggugc     1020

agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc gagguaaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac ggcaagacga     1200

agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac uacgugaaca     1320

agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc uacgacccgc     1380

uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag aagaucaacc     1440

agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac gccggcaaga     1500

gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc cugcuguccc     1560

ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc acccugucca     1620

aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5680
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5680
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug caccucgagg      420

gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug gucucccuca      480

gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac uacaucgaca      540

agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc gagaccguga      600

ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc uccgugaacg      660

ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug cugucccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac accagccccc      900

ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc gaccggggcu      960

gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc gaggucaacc     1080

ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc agcaagaccg     1140

acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac ggcaagacca     1200

agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac uacgucaaca     1320

agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc uacgaccccc     1380

ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag aagaucaacc     1440

agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac gccggcaagu     1500

ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc cuccugagcc     1560

ugaucgccgu ggggcuccug cuguacugca aggcccgguc caccccggug acccugagca     1620

aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5681
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5681
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac uacaucgaca      540

agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc gagaccguca      600

ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg      660

ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc cucucccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac guccagaucg      780

uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc gccuacgucg      840

uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac accucccccc      900

ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc gaccgcggcu      960

gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc gaggucaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac ggcaagacca     1200

agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac ggcugcgacu     1260

acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac uacgucaaca     1320

agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc uacgaccccc     1380

ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag aagaucaacc     1440

agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac gccggcaagu     1500

ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc cuccucuccc     1560

ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc acccucucca     1620

aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5682
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5682
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug caccucgagg      420

gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug gucucucuca      480

gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac uacauugaua      540

aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc gagaccguga      600

uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu ucugucaaug      660

cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug uugagccuca      720

ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau guccagaucg      780

uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua gcauauguag      840

ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau acaagcccac      900

ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg gaucgugggu      960

gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc uguaagguuc     1020

agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc gaggucaauc     1080

ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc uccaaaacag     1140

acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac ggcaagacua     1200

aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau ggaugugauu     1260

augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac uauguuaaca     1320

agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu uaugacccuu     1380

ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag aaaaucaacc     1440

agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac gcgggcaagu     1500

caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu cugcuaaguc     1560

ucaucgccgu cggccugcuu uuguacugca aagcacgcuc uacaccggug acccugagca     1620

aggaccagcu cuccgggaua aacaauaucg cuuucucaaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5683
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5683
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc gagaccguga      600

ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc agcgugaacg      660

ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug cugagccuga      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac accagccccc      900

ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc gacagaggcu      960

gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc ugcaaggugc     1020

agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc gaggugaacc     1080

ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc agcaagaccg     1140

acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac ggcaagacca     1200

agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac uacgugaaca     1320

agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc uacgaccccc     1380

ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag aagaucaacc     1440

agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac gccggcaaga     1500

gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc cugcugagcc     1560

ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug acccugagca     1620

aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5684
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5684
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc caccuggagg      420

gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc gugucccuca      480

gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac uacauugaua      540

aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc gagaccguga      600

uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu uccgugaaug      660

ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug cucucucuga      720

ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau gugcagaucg      780

ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug gcuuaugugg      840

uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau acgucuccuc      900

ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc gaucgcggcu      960

gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg uguaaggugc     1020

agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu gaggugaauc     1080

ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc agcaaaacag     1140

acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac ggcaagacaa     1200

aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau ggaugugauu     1260

auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac uauguuaaca     1320

agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu uaugacccuc     1380

ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag aaaauuaacc     1440

agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac gccggcaaga     1500

gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu cugcuuucuc     1560

ugaucgccgu ggggcuccug cuguacugca aagcuagauc cacaccugug acccuuagca     1620

aggaccagcu cucuggaauu aacaauaucg cguucuccaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5685
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5685
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uauuaauacu uaaagccaac gcaauaacaa caauucucac ugcugucacc uucugcuucg      120

ccucaggcca aaacauaacg gaagaauuuu accaaucaac augcucugca guauccaaag      180

gcuaccuauc ugcucuaaga acagguuggu auacaucagu aauaaccaua gaacuaucaa      240

acauaaaaga aaauaaaugc aacggaacag acgcaaaagu uaaacucaua aaacaagaac      300

uagacaaaua uaaaaacgca guuaccgaac uacaacuacu uaugcaaucc acucccgcca      360

cuggaucagg aucagcaaua gcaucaggag ucgcaguaug uaaagucuua caccucgaag      420

gcgaagucaa uaaaaucaaa uccgcauuac uauccacaaa caaagcaguc guaucccuaa      480

gcggaugcgg aguaucagua cuaacauuua aaguacuaga ccuaaaaaau uacaucgaua      540

aacaacuauu accuauauua aacaaacaau ccugcuccau uucaaauauc gaaaccguaa      600

uagaauuuca acaaaaaaac aacagauuac uagaaauaac aagagaauuu uccguaaaug      660

cuggcguaac aacaccagua uccacauaca ugcucacaaa cuccgaacua cuaucacuaa      720

uaaaugacau gcccauaaca aacgaucaaa aaaaacuaau gucaaauaau guacaaauag      780

uaagacaaca aagcuacucc aucaugugua uaauaaaaga agaaguacua gcauacguag      840

uucaacuacc acuuuacggc guaaucgaca ccccuugcug gaaacuacac accuccccuc      900

uaugcaccac aaacacaaaa gaagguucca acauaugccu uaccagaaca gacagaggcu      960

gguauugcga caacgcagga ucaguuucau uuuuuccaca agcugaaaca ugcaaaguac     1020

aaucaaacag agucuucugc gacacaauga acucaagaac ucuacccuca gaaguaaacc     1080

uauguaacgu agacauuuuc aaccccaaau acgacugcaa aauuaugaca ucaaaaacag     1140

acguuucauc aucaguuauc accucauuag gagcaauagu aagcugcuac ggaaaaacaa     1200

aaugcaccgc cucaaauaaa ugcagaggaa uaauaaaaac uuucuccaac ggaugcgacu     1260

acguuucaaa caaaggugua gacacuguau caguaggaaa cacacuauau uacguaaaua     1320

aacaagaagg aaaaucacuu uaugucaaag gagaaccaau aaucaauuuc uacgacccau     1380

uaguauuccc aucagacgaa uuugaugcuu caauaucaca aguaaacgaa aaaauaaauc     1440

aaucacucgc auuuauacga aaaucagacg aacuacuaca caauguaaac gcaggcaaau     1500

caacaacaaa cauaaugaua acaacaauaa ucauuguaau aauaguaaua cuucuaucuc     1560

uaauagcagu aggauuacuc cucuacugca aagcaagauc aaccccugua acacuaucaa     1620

aagaccaacu uucagguaua aauaauauag cuuuuuccaa uuaaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5686
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5686
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccuaauccu caaagccaac gcgaucacua caauccucac agccgucacc uucugcuucg      120

ccuccggcca aaacaucacc gaggaguucu accaaucaac cugcuccgcc guaucaaaag      180

gauaccuaag cgcccuacgg accggcuggu acacaucugu caucaccauc gaacuaucaa      240

acaucaaaga aaacaaaugc aacggaaccg acgcaaaagu caaacugauu aaacaagaac      300

uagacaaaua caaaaacgca gucaccgaac ugcaauuacu caugcaaagc acaccggcca      360

ccggcucagg cagcgccauc gccuccggcg ucgccgucug caaaguucuc caccucgagg      420

gcgaagucaa caaaauaaaa ucugcccucc ucuccaccaa caaagccguc gucucccuca      480

gcggcugcgg agucuccguc cucaccuuca aaguucucga ucucaagaac uauauugaca      540

aacaacuucu acccauacuc aacaaacaaa gcugcagcau auccaacauc gaaaccguca      600

ucgaguucca acaaaagaac aaccgccucc ucgaaauaac ccgcgaguuc agcguuaacg      660

ccggagucac uaccccuguc uccaccuaca ugcucaccaa cuccgaacuc cuaucacuaa      720

ucaacgacau gcccauaacc aacgaccaga agaaacucau guccaacaac guccaaauug      780

uccgacaaca aagcuacucc auaaugugca uaauaaaaga ggaaguccuc gccuacgucg      840

uacaacugcc ccuuuauggc guaaucgaca cacccugcug gaaacuccac acgucacccc      900

ucugcaccac caacacaaaa gaaggcucga acaucugccu aacacggacu gaccgcggcu      960

gguacugcga caacgccggc uccgucagcu ucuucccaca agccgaaacc ugcaaaguac     1020

aauccaaccg aguauucugc gacaccauga acuccagaac ccuccccuca gaggucaacc     1080

ugugcaacgu agacaucuuc aaccccaaau acgacugcaa aauaaugacc ucaaaaacag     1140

acgucuccuc uuccguaauc accagccucg gagccaucgu cagcugcuac ggcaaaacca     1200

aaugcaccgc cucaaacaaa ugccgcggca ucaucaaaac auucucaaac ggcugcgacu     1260

acgucuccaa caaaggcguc gacacaguaa gcguaggcaa cacacuguac uacgucaaca     1320

aacaagaggg aaaaucacuc uacgucaaag gagaacccau aaucaacuuc uacgaccccc     1380

ucguuuuccc cagcgacgag uucgacgcca gcauauccca agucaacgag aaaauuaacc     1440

aaucccuagc auucauccga aaaucugacg aacugcucca caacgucaac gcgggaaaau     1500

caacaaccaa cauaaugaua accacaauca uaauagucau caucguaauc cuccucagcc     1560

uaaucgcugu cggccuccuc cucuacugca aagcccguuc caccccaguc acacuuucca     1620

aggaccaacu aagcggaaua aacaacaucg cguucucaaa cuaaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  5687
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1) R7456

<400>  5687
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccggcugc ggcgucagcg ugcugaccuu caaggugcug      480

gaccucaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcucc      540

aucagcaaca ucgagacggu gaucgaguuc cagcagaaga acaaccggcu ccuggagauc      600

acccgcgagu ucagcgugaa cgccgggguc accacccccg uguccacgua caugcugacc      660

aacagcgagc uccugucccu gaucaacgac augccgauca ccaacgacca gaagaagcuc      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggcguacgu gguccagcug ccccucuacg gcgugaucga cacccccugc      840

uggaagcugc acacgagccc ccugugcacc accaacacca aggagggguc caacaucugc      900

cucacgcgca ccgaccgggg cugguacugc gacaacgccg gcagcgucuc cuucuucccg      960

caggccgaga ccugcaaggu gcagagcaac cgcguguucu gcgacaccau gaacucccgg     1020

acgcugccca gcgagguaaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgugagc uccagcguga ucaccucccu gggggccauc     1140

gucagcugcu acggcaagac gaagugcacc gccagcaaca agugccgggg gaucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaagggcg uggacaccgu guccgucggg     1260

aacacccugu acuacgugaa caagcaggag ggcaagagcc ucuacgugaa gggggagccc     1320

aucaucaacu ucuacgaccc gcuggucuuc cccuccgacg aguucgacgc gagcaucucc     1380

caggugaacg agaagaucaa ccagagccug gccuucaucc gcaaguccga cgagcugcuc     1440

cacaacguga acgccggcaa gagcacgacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguga uccugcuguc ccucaucgcc guggggcugc ugcucuacug caaggcccgg     1560

agcacgcccg ucacccuguc caaggaccag cugagcggca ucaacaacau cgcguucucc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5688
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt1)

<400>  5688
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccggcagc ggguccgcca ucgccagcgg cguggcggug      360

ugcaaggucc ugcaccucga gggcgaggug aacaagauca aguccgcccu gcugagcacc      420

aacaaggccg uggucucccu cagcgggugc ggcguguccg ugcugacguu caagguccug      480

gaccucaaga acuacaucga caagcagcug cugccgaucc ucaacaagca gagcugcucc      540

aucagcaaca ucgagaccgu gaucgaguuc cagcagaaga acaaccggcu gcuggagauc      600

acccgcgagu ucuccgugaa cgccgggguc accacgcccg ugagcaccua caugcucacc      660

aacagcgagc ugcugucccu caucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu gguccagcuc ccccuguacg gcgugaucga cacgccgugc      840

uggaagcugc acaccagccc ccucugcacc accaacacga aggagggguc caacaucugc      900

cugacccgca ccgaccgggg cugguacugc gacaacgcgg gcuccgugag cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcguguucu gcgacacgau gaacagccgg     1020

acccuccccu ccgaggucaa ccugugcaac guggacaucu ucaacccgaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugucc agcuccguca ucacgagccu gggggccauc     1140

guguccugcu acggcaagac caagugcacc gccagcaaca agugccgggg gaucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaagggcg ucgacacggu gagcgugggg     1260

aacacccucu acuacgucaa caagcaggag ggcaaguccc uguacgugaa gggggagccc     1320

aucaucaacu ucuacgaccc ccugguguuc cccagcgacg aguucgacgc cuccaucagc     1380

caggucaacg agaagaucaa ccagucccuc gcguucaucc gcaagagcga cgagcugcug     1440

cacaacguga acgccggcaa guccaccacc aacaucauga ucaccacgau caucaucgug     1500

aucaucguca uccuccugag ccugaucgcc guggggcucc ugcuguacug caaggcccgg     1560

uccaccccgg ugacccugag caaggaccag cucuccggca ucaacaacau cgccuucagc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5689
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt2)

<400>  5689
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccggcugc ggcgucuccg uccucaccuu caagguccuc      480

gaccucaaga acuacaucga caagcagcuc cuccccaucc ucaacaagca guccugcucc      540

aucuccaaca ucgagaccgu caucgaguuc cagcagaaga acaaccgccu ccucgagauc      600

acccgcgagu ucuccgucaa cgccggcguc accacccccg ucuccaccua caugcucacc      660

aacuccgagc uccucucccu caucaacgac augcccauca ccaacgacca gaagaagcuc      720

auguccaaca acguccagau cguccgccag caguccuacu ccaucaugug caucaucaag      780

gaggaggucc ucgccuacgu cguccagcuc ccccucuacg gcgucaucga cacccccugc      840

uggaagcucc acaccucccc ccucugcacc accaacacca aggagggcuc caacaucugc      900

cucacccgca ccgaccgcgg cugguacugc gacaacgccg gcuccgucuc cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcgucuucu gcgacaccau gaacucccgc     1020

acccuccccu ccgaggucaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgucucc uccuccguca ucaccucccu cggcgccauc     1140

gucuccugcu acggcaagac caagugcacc gccuccaaca agugccgcgg caucaucaag     1200

accuucucca acggcugcga cuacgucucc aacaagggcg ucgacaccgu cuccgucggc     1260

aacacccucu acuacgucaa caagcaggag ggcaaguccc ucuacgucaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccucgucuuc cccuccgacg aguucgacgc cuccaucucc     1380

caggucaacg agaagaucaa ccagucccuc gccuucaucc gcaaguccga cgagcuccuc     1440

cacaacguca acgccggcaa guccaccacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguca uccuccucuc ccucaucgcc gucggccucc uccucuacug caaggcccgc     1560

uccacccccg ucacccucuc caaggaccag cucuccggca ucaacaacau cgccuucucc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5690
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt3)

<400>  5690
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccggcucg gggucagcua uagcaagcgg aguggccguc      360

uguaaggugu ugcaccucga gggcgaaguu aacaaaauca agagugcucu gcuguccacg      420

aauaaagccg uggucucucu cagcgguugc gggguguccg uauuaacuuu uaagguucug      480

gaccuuaaga acuacauuga uaaacaauug cugccuaucc uaaauaagca gucauguagu      540

auuagcaaca ucgagaccgu gauagaguuc cagcagaaaa auaacaggcu ccuggaaauu      600

acacgggagu uuucugucaa ugcgggagug acuaccccag uguccacaua uaugcuuacc      660

aacucagaac uguugagccu caucaaugac augccgauua cgaacgauca aaagaaacug      720

augaguaaca auguccagau cguucgccag cagucuuacu ccaucaugug cauuauaaag      780

gaggaagugu uagcauaugu agugcaacug ccccucuacg gcgucaucga cacuccuugu      840

uggaaacuuc auacaagccc acugugcacc acuaacacaa aggagggcuc gaauauuugu      900

uugacccgaa cggaucgugg gugguacugc gacaacgccg gaucuguguc cuucuuuccc      960

caggcugaaa ccuguaaggu ucagucaaau agaguguucu gcgauacaau gaacaguaga     1020

acucugccua gcgaggucaa ucucugcaac guggacaucu uuaauccaaa auaugauugu     1080

aagauaauga ccuccaaaac agacguaucu agcucaguua uuaccagucu gggugccauc     1140

guguccugcu acggcaagac uaaauguaca gcaagcaaca agugcagggg gaucauuaag     1200

accuucucua auggauguga uuaugucuca aacaaaggcg uggacacugu cagugugggu     1260

aauacgcuuu acuauguuaa caagcaagag gggaaaagcc uguacgugaa gggagaaccc     1320

aucauuaauu uuuaugaccc uuugguauuc ccauccgaug aguuugacgc uucuauaucg     1380

caggucaacg agaaaaucaa ccagagccuc gccuucauuc ggaaguccga ugaacuguua     1440

cacaauguga acgcgggcaa gucaacaacc aauaucauga ucacuaccau uauaaucguu     1500

auuaucguga uucugcuaag ucucaucgcc gucggccugc uuuuguacug caaagcacgc     1560

ucuacaccgg ugacccugag caaggaccag cucuccggga uaaacaauau cgcuuucuca     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5691
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt4)

<400>  5691
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcggcugc ggcgugagcg ugcugaccuu caaggugcug      480

gaccugaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcagc      540

aucagcaaca ucgagaccgu gaucgaguuc cagcagaaga acaacagacu gcuggagauc      600

accagagagu ucagcgugaa cgccggcgug accacccccg ugagcaccua caugcugacc      660

aacagcgagc ugcugagccu gaucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cgugagacag cagagcuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu ggugcagcug ccccuguacg gcgugaucga cacccccugc      840

uggaagcugc acaccagccc ccugugcacc accaacacca aggagggcag caacaucugc      900

cugaccagaa ccgacagagg cugguacugc gacaacgccg gcagcgugag cuucuucccc      960

caggccgaga ccugcaaggu gcagagcaac agaguguucu gcgacaccau gaacagcaga     1020

acccugccca gcgaggugaa ccugugcaac guggacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugagc agcagcguga ucaccagccu gggcgccauc     1140

gugagcugcu acggcaagac caagugcacc gccagcaaca agugcagagg caucaucaag     1200

accuucagca acggcugcga cuacgugagc aacaagggcg uggacaccgu gagcgugggc     1260

aacacccugu acuacgugaa caagcaggag ggcaagagcc uguacgugaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccugguguuc cccagcgacg aguucgacgc cagcaucagc     1380

caggugaacg agaagaucaa ccagagccug gccuucauca gaaagagcga cgagcugcug     1440

cacaacguga acgccggcaa gagcaccacc aacaucauga ucaccaccau caucaucgug     1500

aucaucguga uccugcugag ccugaucgcc gugggccugc ugcuguacug caaggccaga     1560

agcacccccg ugacccugag caaggaccag cugagcggca ucaacaacau cgccuucagc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5692
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt5)

<400>  5692
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacagggucu ggaagcgcua uugccuccgg cgucgcggug      360

uguaagguuc uccaccugga gggggaagug aacaaaauca agagcgcccu ucugucuacc      420

aauaaagcug ucgugucccu cagcggaugc ggcguuucug ugcugacauu uaagguccuu      480

gaccugaaga acuacauuga uaaacaacuc cugccuaucc ugaauaagca guccuguagc      540

auuucuaaca ucgagaccgu gauugaguuc cagcagaaaa auaaccggcu ccuggaaauc      600

acgcgcgagu uuuccgugaa ugccggcguc acaaccccgg uuagcacaua uaugcuuacc      660

aacuccgaac ugcucucucu gaucaaugac augcccauua ccaacgauca aaagaaacuu      720

augagcaaca augugcagau cgugagacag caguccuaca gcauuaugug caucauuaag      780

gaggaagucc uggcuuaugu gguucaacuc ccucuguacg gggugaucga cacacccugu      840

uggaaacugc auacgucucc ucucugcacc acaaacacca aggagggauc caauaucugu      900

cugacacgga ccgaucgcgg cugguacugc gacaacgccg ggagcgucuc uuucuuuccc      960

caggcggaaa cguguaaggu gcagagcaau agaguuuucu gcgauacaau gaacuccaga     1020

acccugccuu cugaggugaa ucucugcaac gucgacauuu uuaauccgaa auaugauugu     1080

aagaucauga ccagcaaaac agacgugucc agcucuguca uuaccucccu gggagccauc     1140

gugagcugcu acggcaagac aaaauguacg gcuucuaaca agugccgggg gauuaucaag     1200

accuucucca auggauguga uuauguuagc aacaaaggcg uggacacagu cuccgugggc     1260

aauacccuuu acuauguuaa caagcaagag gggaaaucuc uguacgugaa gggagaaccc     1320

aucauuaauu uuuaugaccc ucucgucuuc cccagcgaug aguuugacgc cuccaucucu     1380

caggugaacg agaaaauuaa ccagagccug gcuuucaucc gcaaguccga ugaacugcuc     1440

cacaauguga acgccggcaa gagcacaacc aauauuauga ucacgaccau uaucaucguu     1500

auuaucguca uucugcuuuc ucugaucgcc guggggcucc ugcuguacug caaagcuaga     1560

uccacaccug ugacccuuag caaggaccag cucucuggaa uuaacaauau cgcguucucc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5693
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt6)

<400>  5693
gggagaaagc uuaccaugga acuauuaaua cuuaaagcca acgcaauaac aacaauucuc       60

acugcuguca ccuucugcuu cgccucaggc caaaacauaa cggaagaauu uuaccaauca      120

acaugcucug caguauccaa aggcuaccua ucugcucuaa gaacagguug guauacauca      180

guaauaacca uagaacuauc aaacauaaaa gaaaauaaau gcaacggaac agacgcaaaa      240

guuaaacuca uaaaacaaga acuagacaaa uauaaaaacg caguuaccga acuacaacua      300

cuuaugcaau ccacucccgc cacuggauca ggaucagcaa uagcaucagg agucgcagua      360

uguaaagucu uacaccucga aggcgaaguc aauaaaauca aauccgcauu acuauccaca      420

aacaaagcag ucguaucccu aagcggaugc ggaguaucag uacuaacauu uaaaguacua      480

gaccuaaaaa auuacaucga uaaacaacua uuaccuauau uaaacaaaca auccugcucc      540

auuucaaaua ucgaaaccgu aauagaauuu caacaaaaaa acaacagauu acuagaaaua      600

acaagagaau uuuccguaaa ugcuggcgua acaacaccag uauccacaua caugcucaca      660

aacuccgaac uacuaucacu aauaaaugac augcccauaa caaacgauca aaaaaaacua      720

augucaaaua auguacaaau aguaagacaa caaagcuacu ccaucaugug uauaauaaaa      780

gaagaaguac uagcauacgu aguucaacua ccacuuuacg gcguaaucga caccccuugc      840

uggaaacuac acaccucccc ucuaugcacc acaaacacaa aagaagguuc caacauaugc      900

cuuaccagaa cagacagagg cugguauugc gacaacgcag gaucaguuuc auuuuuucca      960

caagcugaaa caugcaaagu acaaucaaac agagucuucu gcgacacaau gaacucaaga     1020

acucuacccu cagaaguaaa ccuauguaac guagacauuu ucaaccccaa auacgacugc     1080

aaaauuauga caucaaaaac agacguuuca ucaucaguua ucaccucauu aggagcaaua     1140

guaagcugcu acggaaaaac aaaaugcacc gccucaaaua aaugcagagg aauaauaaaa     1200

acuuucucca acggaugcga cuacguuuca aacaaaggug uagacacugu aucaguagga     1260

aacacacuau auuacguaaa uaaacaagaa ggaaaaucac uuuaugucaa aggagaacca     1320

auaaucaauu ucuacgaccc auuaguauuc ccaucagacg aauuugaugc uucaauauca     1380

caaguaaacg aaaaaauaaa ucaaucacuc gcauuuauac gaaaaucaga cgaacuacua     1440

cacaauguaa acgcaggcaa aucaacaaca aacauaauga uaacaacaau aaucauugua     1500

auaauaguaa uacuucuauc ucuaauagca guaggauuac uccucuacug caaagcaaga     1560

ucaaccccug uaacacuauc aaaagaccaa cuuucaggua uaaauaauau agcuuuuucc     1620

aauuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5694
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut5 (opt11)

<400>  5694
gggagaaagc uuaccaugga gcuccuaauc cucaaagcca acgcgaucac uacaauccuc       60

acagccguca ccuucugcuu cgccuccggc caaaacauca ccgaggaguu cuaccaauca      120

accugcuccg ccguaucaaa aggauaccua agcgcccuac ggaccggcug guacacaucu      180

gucaucacca ucgaacuauc aaacaucaaa gaaaacaaau gcaacggaac cgacgcaaaa      240

gucaaacuga uuaaacaaga acuagacaaa uacaaaaacg cagucaccga acugcaauua      300

cucaugcaaa gcacaccggc caccggcuca ggcagcgcca ucgccuccgg cgucgccguc      360

ugcaaaguuc uccaccucga gggcgaaguc aacaaaauaa aaucugcccu ccucuccacc      420

aacaaagccg ucgucucccu cagcggcugc ggagucuccg uccucaccuu caaaguucuc      480

gaucucaaga acuauauuga caaacaacuu cuacccauac ucaacaaaca aagcugcagc      540

auauccaaca ucgaaaccgu caucgaguuc caacaaaaga acaaccgccu ccucgaaaua      600

acccgcgagu ucagcguuaa cgccggaguc acuaccccug ucuccaccua caugcucacc      660

aacuccgaac uccuaucacu aaucaacgac augcccauaa ccaacgacca gaagaaacuc      720

auguccaaca acguccaaau uguccgacaa caaagcuacu ccauaaugug cauaauaaaa      780

gaggaagucc ucgccuacgu cguacaacug ccccuuuaug gcguaaucga cacacccugc      840

uggaaacucc acacgucacc ccucugcacc accaacacaa aagaaggcuc gaacaucugc      900

cuaacacgga cugaccgcgg cugguacugc gacaacgccg gcuccgucag cuucuuccca      960

caagccgaaa ccugcaaagu acaauccaac cgaguauucu gcgacaccau gaacuccaga     1020

acccuccccu cagaggucaa ccugugcaac guagacaucu ucaaccccaa auacgacugc     1080

aaaauaauga ccucaaaaac agacgucucc ucuuccguaa ucaccagccu cggagccauc     1140

gucagcugcu acggcaaaac caaaugcacc gccucaaaca aaugccgcgg caucaucaaa     1200

acauucucaa acggcugcga cuacgucucc aacaaaggcg ucgacacagu aagcguaggc     1260

aacacacugu acuacgucaa caaacaagag ggaaaaucac ucuacgucaa aggagaaccc     1320

auaaucaacu ucuacgaccc ccucguuuuc cccagcgacg aguucgacgc cagcauaucc     1380

caagucaacg agaaaauuaa ccaaucccua gcauucaucc gaaaaucuga cgaacugcuc     1440

cacaacguca acgcgggaaa aucaacaacc aacauaauga uaaccacaau cauaauaguc     1500

aucaucguaa uccuccucag ccuaaucgcu gucggccucc uccucuacug caaagcccgu     1560

uccaccccag ucacacuuuc caaggaccaa cuaagcggaa uaaacaacau cgcguucuca     1620

aacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  5695
<211>  515
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5695

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Gly 
    130                 135                 140                 


Cys Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr 
145                 150                 155                 160 


Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile 
                165                 170                 175     


Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu 
            180                 185                 190         


Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro 
        195                 200                 205             


Val Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn 
    210                 215                 220                 


Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val 
225                 230                 235                 240 


Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu 
                245                 250                 255     


Glu Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp 
            260                 265                 270         


Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr 
        275                 280                 285             


Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr 
    290                 295                 300                 


Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys 
305                 310                 315                 320 


Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Arg Thr 
                325                 330                 335     


Leu Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys 
            340                 345                 350         


Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val 
        355                 360                 365             


Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys 
    370                 375                 380                 


Thr Ala Ser Asn Lys Cys Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly 
385                 390                 395                 400 


Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn 
                405                 410                 415     


Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys 
            420                 425                 430         


Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp 
        435                 440                 445             


Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser 
    450                 455                 460                 


Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala 
465                 470                 475                 480 


Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile 
                485                 490                 495     


Ile Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys 
            500                 505                 510         


Lys Ala Arg 
        515 


<210>  5696
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5696
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucuccg gcugcggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      540

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      600

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      660

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      780

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      840

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac      900

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc      960

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccggacgcu gcccagcgag     1020

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1140

aagacgaagu gcaccgccag caacaagugc cgggggauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1260

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1320

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1380

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1440

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1500

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccgguga                  1548


<210>  5697
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5697
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agcuccugau gcaguccacc      300

cccgccaccg gcagcggguc cgccaucgcc agcggcgugg cggugugcaa gguccugcac      360

cucgagggcg aggugaacaa gaucaagucc gcccugcuga gcaccaacaa ggccgugguc      420

ucccucagcg ggugcggcgu guccgugcug acguucaagg uccuggaccu caagaacuac      480

aucgacaagc agcugcugcc gauccucaac aagcagagcu gcuccaucag caacaucgag      540

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      600

gugaacgccg gggucaccac gcccgugagc accuacaugc ucaccaacag cgagcugcug      660

ucccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggucc agcucccccu guacggcgug aucgacacgc cgugcuggaa gcugcacacc      840

agcccccucu gcaccaccaa cacgaaggag ggguccaaca ucugccugac ccgcaccgac      900

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccggacccu ccccuccgag     1020

gucaaccugu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1080

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1140

aagaccaagu gcaccgccag caacaagugc cgggggauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg uggggaacac ccucuacuac     1260

gucaacaagc aggagggcaa gucccuguac gugaaggggg agcccaucau caacuucuac     1320

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1380

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1440

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1500

cugagccuga ucgccguggg gcuccugcug uacugcaagg cccgguga                  1548


<210>  5698
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5698
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucuccg gcugcggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      480

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      540

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      600

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      660

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      720

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      780

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      840

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac      900

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccgcacccu ccccuccgag     1020

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1140

aagaccaagu gcaccgccuc caacaagugc cgcggcauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1260

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1320

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1380

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1440

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1500

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuga                  1548


<210>  5699
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5699
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agcuucugau gcagucuaca      300

cccgccaccg gcucgggguc agcuauagca agcggagugg ccgucuguaa gguguugcac      360

cucgagggcg aaguuaacaa aaucaagagu gcucugcugu ccacgaauaa agccgugguc      420

ucucucagcg guugcggggu guccguauua acuuuuaagg uucuggaccu uaagaacuac      480

auugauaaac aauugcugcc uauccuaaau aagcagucau guaguauuag caacaucgag      540

accgugauag aguuccagca gaaaaauaac aggcuccugg aaauuacacg ggaguuuucu      600

gucaaugcgg gagugacuac cccagugucc acauauaugc uuaccaacuc agaacuguug      660

agccucauca augacaugcc gauuacgaac gaucaaaaga aacugaugag uaacaauguc      720

cagaucguuc gccagcaguc uuacuccauc augugcauua uaaaggagga aguguuagca      780

uauguagugc aacugccccu cuacggcguc aucgacacuc cuuguuggaa acuucauaca      840

agcccacugu gcaccacuaa cacaaaggag ggcucgaaua uuuguuugac ccgaacggau      900

cguggguggu acugcgacaa cgccggaucu guguccuucu uuccccaggc ugaaaccugu      960

aagguucagu caaauagagu guucugcgau acaaugaaca guagaacucu gccuagcgag     1020

gucaaucucu gcaacgugga caucuuuaau ccaaaauaug auuguaagau aaugaccucc     1080

aaaacagacg uaucuagcuc aguuauuacc agucugggug ccaucguguc cugcuacggc     1140

aagacuaaau guacagcaag caacaagugc agggggauca uuaagaccuu cucuaaugga     1200

ugugauuaug ucucaaacaa aggcguggac acugucagug uggguaauac gcuuuacuau     1260

guuaacaagc aagaggggaa aagccuguac gugaagggag aacccaucau uaauuuuuau     1320

gacccuuugg uauucccauc cgaugaguuu gacgcuucua uaucgcaggu caacgagaaa     1380

aucaaccaga gccucgccuu cauucggaag uccgaugaac uguuacacaa ugugaacgcg     1440

ggcaagucaa caaccaauau caugaucacu accauuauaa ucguuauuau cgugauucug     1500

cuaagucuca ucgccgucgg ccugcuuuug uacugcaaag cacgcuga                  1548


<210>  5700
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5700
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagcg gcugcggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      540

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      600

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      660

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      840

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac      900

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc      960

aaggugcaga gcaacagagu guucugcgac accaugaaca gcagaacccu gcccagcgag     1020

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1080

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1140

aagaccaagu gcaccgccag caacaagugc agaggcauca ucaagaccuu cagcaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1260

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1320

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1380

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1440

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1500

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagauga                  1548


<210>  5701
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5701
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agcugcugau gcaguccacc      300

cccgccacag ggucuggaag cgcuauugcc uccggcgucg cgguguguaa gguucuccac      360

cuggaggggg aagugaacaa aaucaagagc gcccuucugu cuaccaauaa agcugucgug      420

ucccucagcg gaugcggcgu uucugugcug acauuuaagg uccuugaccu gaagaacuac      480

auugauaaac aacuccugcc uauccugaau aagcaguccu guagcauuuc uaacaucgag      540

accgugauug aguuccagca gaaaaauaac cggcuccugg aaaucacgcg cgaguuuucc      600

gugaaugccg gcgucacaac cccgguuagc acauauaugc uuaccaacuc cgaacugcuc      660

ucucugauca augacaugcc cauuaccaac gaucaaaaga aacuuaugag caacaaugug      720

cagaucguga gacagcaguc cuacagcauu augugcauca uuaaggagga aguccuggcu      780

uaugugguuc aacucccucu guacggggug aucgacacac ccuguuggaa acugcauacg      840

ucuccucucu gcaccacaaa caccaaggag ggauccaaua ucugucugac acggaccgau      900

cgcggcuggu acugcgacaa cgccgggagc gucucuuucu uuccccaggc ggaaacgugu      960

aaggugcaga gcaauagagu uuucugcgau acaaugaacu ccagaacccu gccuucugag     1020

gugaaucucu gcaacgucga cauuuuuaau ccgaaauaug auuguaagau caugaccagc     1080

aaaacagacg uguccagcuc ugucauuacc ucccugggag ccaucgugag cugcuacggc     1140

aagacaaaau guacggcuuc uaacaagugc cgggggauua ucaagaccuu cuccaaugga     1200

ugugauuaug uuagcaacaa aggcguggac acagucuccg ugggcaauac ccuuuacuau     1260

guuaacaagc aagaggggaa aucucuguac gugaagggag aacccaucau uaauuuuuau     1320

gacccucucg ucuuccccag cgaugaguuu gacgccucca ucucucaggu gaacgagaaa     1380

auuaaccaga gccuggcuuu cauccgcaag uccgaugaac ugcuccacaa ugugaacgcc     1440

ggcaagagca caaccaauau uaugaucacg accauuauca ucguuauuau cgucauucug     1500

cuuucucuga ucgccguggg gcuccugcug uacugcaaag cuagauga                  1548


<210>  5702
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5702
auggaacuuu uaauacugaa agcaaaugcc aucacaacca uacuaacugc cgucacauuc       60

ugcuuugcau caggacaaaa cauaacagaa gaauuuuacc aauccacaug cucagcagua      120

ucaaaaggau aucuaucggc acuuagaacu ggaugguaca caaguguuau aacuauagaa      180

cucucaaaca uaaaagaaaa caaaugcaau ggaacagacg caaaaguaaa acuaauaaaa      240

caagaacucg auaaauauaa aaaugcagua accgaacuac aacuauuaau gcaaagcaca      300

cccgcaacag gcagcggauc agcaauagca agcggagucg caguauguaa aguacuacau      360

cuagaaggag aagucaacaa aaucaaaucu gcacuucuau ccacaaacaa agcuguagua      420

ucccuauccg gaugcggagu cucaguauua acuuuuaaag uacuagaccu uaaaaacuac      480

auagauaaac aacuauuacc aauacuaaau aaacaaucau gcagcauauc caauauagag      540

acaguaauug aauuucaaca aaaaaacaac agauuacuag aaauuacucg ugaauuuucc      600

guaaaugccg gagucacaac accaguauca accuauaugc uaacaaacag cgaacuacuu      660

agcuuaauaa augacaugcc aauaacaaau gaccaaaaaa aacuuauguc aaauaacgua      720

caaaucguca gacaacaauc cuacucuaua auguguauaa uuaaagaaga aguccuagca      780

uacguaguuc aauuaccacu cuauggagua auagauacac caugcuggaa acuacacacg      840

ucaccacuau guacaacaaa cacaaaagaa ggauccaaua uaugccuaac aagaaccgac      900

agaggcuggu auugugacaa cgcaggaucc guuucauucu ucccacaagc agaaaccugu      960

aaaguacaau cuaauagagu auuuugcgac acaaugaaca guagaacacu accaagcgag     1020

guuaaucuau guaacguaga cauauucaau ccaaaauaug auugcaaaau aaugacauca     1080

aaaacagaug uaucgucgag uguaauaaca agucugggag cuauaguaag cugcuacggc     1140

aagacgaaau guaccgcuuc aaauaaaugc agaggaauca uuaaaacauu cucgaacgga     1200

ugcgacuacg uaaguaauaa aggugucgac accguaucag uagggaauac auuauacuac     1260

gucaacaaac aagaaggaaa aucucuauau guaaaaggag aaccaauaau aaauuucuau     1320

gacccucuag uauucccauc agaugaauuu gacgcuucca uaucacaagu aaacgaaaaa     1380

aucaaucaau cuuuagcauu cauacgaaaa agugaugaac uccuacacaa cgucaacgca     1440

ggaaaaagca caacaaauau aaugaucaca acaaucauca uaguaauaau aguaauacua     1500

cuaucauuaa uagcaguagg auuauugcuu uacugcaaag cacgauag                  1548


<210>  5703
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut5

<400>  5703
auggaacucc ucauccucaa agccaacgcc auaaccacaa uacucaccgc cguaaccuuc       60

ugcuuugcgu cgggacaaaa caucaccgaa gaguucuacc aauccacuug cuccgcagua      120

agcaaaggau accucuccgc ccugcgaacc gguugguaca caucagucau cacaaucgaa      180

cucucaaaca uaaaagaaaa caaaugcaac ggcaccgacg caaaggucaa auuaaucaag      240

caagaacuag acaaauacaa aaacgccguc acagaacucc agcugcuaau gcagagcaca      300

cccgcaacug gcagcggauc cgccaucgca ucaggagucg ccgugugcaa aguccuacac      360

cucgaaggag aagugaacaa aaucaaauca gcccuacucu ccaccaacaa ggccgucguc      420

ucccucuccg gcugcggugu cuccguccua accuucaaag ugcuagaccu caagaacuac      480

aucgacaaac aacuccuacc aauacucaac aagcaaucuu gcuccaucuc caacaucgaa      540

accguaaucg aguuccaaca gaagaacaac cgccuccucg aaaucacccg cgaguucucu      600

gucaacgcag gggucaccac ucccgucucc acauacaugc ucacaaacuc cgaacuccuc      660

agccucauca acgacaugcc cauaaccaac gaccagaaaa agcuaaugag caauaacguc      720

caaaucguua gacaacaaag uuauuccauc augugcauca ucaaagaaga aguccucgcc      780

uacgucguac aacucccccu cuauggcguc aucgacaccc ccugcuggaa acugcacaca      840

ucaccccucu gcaccacaaa caccaaagaa ggcucaaaca ucugccuaac ucgcaccgac      900

cgcggcuggu acugcgacaa cgccggcagc guaucauucu uuccccaagc cgaaacaugc      960

aaaguucaau ccaaccgcgu cuucugcgac acaaugaacu ccagaacgcu ccccagcgaa     1020

gucaaccucu guaacguaga caucuucaac ccuaaguacg acugcaaaau caugaccucc     1080

aaaacugaug uauccuccuc cgucaucaca ucccugggcg ccaucgucag cugcuacggc     1140

aaaacaaaau gcacugccuc aaacaaaugc cgagguauca uaaagaccuu cucaaacgga     1200

ugcgauuacg ucagcaacaa aggcgucgac accgucagug ucggcaacac ccucuacuac     1260

gucaacaaac aagaaggaaa aucccucuac gucaaaggcg aacccaucau caacuucuac     1320

gacccccucg ucuuccccag cgacgaguuc gacgccucca ucucacaagu caacgaaaag     1380

auaaaccaau cucuagccuu cauccgcaaa uccgaugaac uccugcauaa cgucaacgcc     1440

ggcaaaucca ccacaaacau caugaucacu accauaauca ucgucauaau cguaauccuc     1500

cuaucucuua ucgcagucgg ccuacuacuc uacugcaaag cccgcuaa                  1548


<210>  5704
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5704
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5705
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5705
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5706
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5706
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5707
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5707
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5708
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5708
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5709
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5709
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5710
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5710
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacugaaagc aaaugccauc acaaccauac      120

uaacugccgu cacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

ccacaugcuc agcaguauca aaaggauauc uaucggcacu uagaacugga ugguacacaa      240

guguuauaac uauagaacuc ucaaacauaa aagaaaacaa augcaaugga acagacgcaa      300

aaguaaaacu aauaaaacaa gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac      360

uauuaaugca aagcacaccc gcaacaggca gcggaucagc aauagcaagc ggagucgcag      420

uauguaaagu acuacaucua gaaggagaag ucaacaaaau caaaucugca cuucuaucca      480

caaacaaagc uguaguaucc cuauccggau gcggagucuc aguauuaacu uuuaaaguac      540

uagaccuuaa aaacuacaua gauaaacaac uauuaccaau acuaaauaaa caaucaugca      600

gcauauccaa uauagagaca guaauugaau uucaacaaaa aaacaacaga uuacuagaaa      660

uuacucguga auuuuccgua aaugccggag ucacaacacc aguaucaacc uauaugcuaa      720

caaacagcga acuacuuagc uuaauaaaug acaugccaau aacaaaugac caaaaaaaac      780

uuaugucaaa uaacguacaa aucgucagac aacaauccua cucuauaaug uguauaauua      840

aagaagaagu ccuagcauac guaguucaau uaccacucua uggaguaaua gauacaccau      900

gcuggaaacu acacacguca ccacuaugua caacaaacac aaaagaagga uccaauauau      960

gccuaacaag aaccgacaga ggcugguauu gugacaacgc aggauccguu ucauucuucc     1020

cacaagcaga aaccuguaaa guacaaucua auagaguauu uugcgacaca augaacagua     1080

gaacacuacc aagcgagguu aaucuaugua acguagacau auucaaucca aaauaugauu     1140

gcaaaauaau gacaucaaaa acagauguau cgucgagugu aauaacaagu cugggagcua     1200

uaguaagcug cuacggcaag acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua     1260

aaacauucuc gaacggaugc gacuacguaa guaauaaagg ugucgacacc guaucaguag     1320

ggaauacauu auacuacguc aacaaacaag aaggaaaauc ucuauaugua aaaggagaac     1380

caauaauaaa uuucuaugac ccucuaguau ucccaucaga ugaauuugac gcuuccauau     1440

cacaaguaaa cgaaaaaauc aaucaaucuu uagcauucau acgaaaaagu gaugaacucc     1500

uacacaacgu caacgcagga aaaagcacaa caaauauaau gaucacaaca aucaucauag     1560

uaauaauagu aauacuacua ucauuaauag caguaggauu auugcuuuac ugcaaagcac     1620

gauagggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5711
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5711
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacaauac      120

ucaccgccgu aaccuucugc uuugcgucgg gacaaaacau caccgaagag uucuaccaau      180

ccacuugcuc cgcaguaagc aaaggauacc ucuccgcccu gcgaaccggu ugguacacau      240

cagucaucac aaucgaacuc ucaaacauaa aagaaaacaa augcaacggc accgacgcaa      300

aggucaaauu aaucaagcaa gaacuagaca aauacaaaaa cgccgucaca gaacuccagc      360

ugcuaaugca gagcacaccc gcaacuggca gcggauccgc caucgcauca ggagucgccg      420

ugugcaaagu ccuacaccuc gaaggagaag ugaacaaaau caaaucagcc cuacucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggugucuc cguccuaacc uucaaagugc      540

uagaccucaa gaacuacauc gacaaacaac uccuaccaau acucaacaag caaucuugcu      600

ccaucuccaa caucgaaacc guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucucuguc aacgcagggg ucaccacucc cgucuccaca uacaugcuca      720

caaacuccga acuccucagc cucaucaacg acaugcccau aaccaacgac cagaaaaagc      780

uaaugagcaa uaacguccaa aucguuagac aacaaaguua uuccaucaug ugcaucauca      840

aagaagaagu ccucgccuac gucguacaac ucccccucua uggcgucauc gacacccccu      900

gcuggaaacu gcacacauca ccccucugca ccacaaacac caaagaaggc ucaaacaucu      960

gccuaacucg caccgaccgc ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc     1020

cccaagccga aacaugcaaa guucaaucca accgcgucuu cugcgacaca augaacucca     1080

gaacgcuccc cagcgaaguc aaccucugua acguagacau cuucaacccu aaguacgacu     1140

gcaaaaucau gaccuccaaa acugauguau ccuccuccgu caucacaucc cugggcgcca     1200

ucgucagcug cuacggcaaa acaaaaugca cugccucaaa caaaugccga gguaucauaa     1260

agaccuucuc aaacggaugc gauuacguca gcaacaaagg cgucgacacc gucagugucg     1320

gcaacacccu cuacuacguc aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac     1380

ccaucaucaa cuucuacgac ccccucgucu uccccagcga cgaguucgac gccuccaucu     1440

cacaagucaa cgaaaagaua aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc     1500

ugcauaacgu caacgccggc aaauccacca caaacaucau gaucacuacc auaaucaucg     1560

ucauaaucgu aauccuccua ucucuuaucg cagucggccu acuacucuac ugcaaagccc     1620

gcuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  5712
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5712
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5713
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5713
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5714
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5714
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5715
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5715
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5716
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5716
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5717
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5717
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5718
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5718
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acugaaagca      120

aaugccauca caaccauacu aacugccguc acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc cacaugcuca gcaguaucaa aaggauaucu aucggcacuu      240

agaacuggau gguacacaag uguuauaacu auagaacucu caaacauaaa agaaaacaaa      300

ugcaauggaa cagacgcaaa aguaaaacua auaaaacaag aacucgauaa auauaaaaau      360

gcaguaaccg aacuacaacu auuaaugcaa agcacacccg caacaggcag cggaucagca      420

auagcaagcg gagucgcagu auguaaagua cuacaucuag aaggagaagu caacaaaauc      480

aaaucugcac uucuauccac aaacaaagcu guaguauccc uauccggaug cggagucuca      540

guauuaacuu uuaaaguacu agaccuuaaa aacuacauag auaaacaacu auuaccaaua      600

cuaaauaaac aaucaugcag cauauccaau auagagacag uaauugaauu ucaacaaaaa      660

aacaacagau uacuagaaau uacucgugaa uuuuccguaa augccggagu cacaacacca      720

guaucaaccu auaugcuaac aaacagcgaa cuacuuagcu uaauaaauga caugccaaua      780

acaaaugacc aaaaaaaacu uaugucaaau aacguacaaa ucgucagaca acaauccuac      840

ucuauaaugu guauaauuaa agaagaaguc cuagcauacg uaguucaauu accacucuau      900

ggaguaauag auacaccaug cuggaaacua cacacgucac cacuauguac aacaaacaca      960

aaagaaggau ccaauauaug ccuaacaaga accgacagag gcugguauug ugacaacgca     1020

ggauccguuu cauucuuccc acaagcagaa accuguaaag uacaaucuaa uagaguauuu     1080

ugcgacacaa ugaacaguag aacacuacca agcgagguua aucuauguaa cguagacaua     1140

uucaauccaa aauaugauug caaaauaaug acaucaaaaa cagauguauc gucgagugua     1200

auaacaaguc ugggagcuau aguaagcugc uacggcaaga cgaaauguac cgcuucaaau     1260

aaaugcagag gaaucauuaa aacauucucg aacggaugcg acuacguaag uaauaaaggu     1320

gucgacaccg uaucaguagg gaauacauua uacuacguca acaaacaaga aggaaaaucu     1380

cuauauguaa aaggagaacc aauaauaaau uucuaugacc cucuaguauu cccaucagau     1440

gaauuugacg cuuccauauc acaaguaaac gaaaaaauca aucaaucuuu agcauucaua     1500

cgaaaaagug augaacuccu acacaacguc aacgcaggaa aaagcacaac aaauauaaug     1560

aucacaacaa ucaucauagu aauaauagua auacuacuau cauuaauagc aguaggauua     1620

uugcuuuacu gcaaagcacg auagggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5719
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5719
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacaauacu caccgccgua accuucugcu uugcgucggg acaaaacauc      180

accgaagagu ucuaccaauc cacuugcucc gcaguaagca aaggauaccu cuccgcccug      240

cgaaccgguu gguacacauc agucaucaca aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa ggucaaauua aucaagcaag aacuagacaa auacaaaaac      360

gccgucacag aacuccagcu gcuaaugcag agcacacccg caacuggcag cggauccgcc      420

aucgcaucag gagucgccgu gugcaaaguc cuacaccucg aaggagaagu gaacaaaauc      480

aaaucagccc uacucuccac caacaaggcc gucgucuccc ucuccggcug cggugucucc      540

guccuaaccu ucaaagugcu agaccucaag aacuacaucg acaaacaacu ccuaccaaua      600

cucaacaagc aaucuugcuc caucuccaac aucgaaaccg uaaucgaguu ccaacagaag      660

aacaaccgcc uccucgaaau cacccgcgag uucucuguca acgcaggggu caccacuccc      720

gucuccacau acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugcccaua      780

accaacgacc agaaaaagcu aaugagcaau aacguccaaa ucguuagaca acaaaguuau      840

uccaucaugu gcaucaucaa agaagaaguc cucgccuacg ucguacaacu cccccucuau      900

ggcgucaucg acacccccug cuggaaacug cacacaucac cccucugcac cacaaacacc      960

aaagaaggcu caaacaucug ccuaacucgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcagcguau cauucuuucc ccaagccgaa acaugcaaag uucaauccaa ccgcgucuuc     1080

ugcgacacaa ugaacuccag aacgcucccc agcgaaguca accucuguaa cguagacauc     1140

uucaacccua aguacgacug caaaaucaug accuccaaaa cugauguauc cuccuccguc     1200

aucacauccc ugggcgccau cgucagcugc uacggcaaaa caaaaugcac ugccucaaac     1260

aaaugccgag guaucauaaa gaccuucuca aacggaugcg auuacgucag caacaaaggc     1320

gucgacaccg ucagugucgg caacacccuc uacuacguca acaaacaaga aggaaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagcgac     1440

gaguucgacg ccuccaucuc acaagucaac gaaaagauaa accaaucucu agccuucauc     1500

cgcaaauccg augaacuccu gcauaacguc aacgccggca aauccaccac aaacaucaug     1560

aucacuacca uaaucaucgu cauaaucgua auccuccuau cucuuaucgc agucggccua     1620

cuacucuacu gcaaagcccg cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  5720
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5720
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5721
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5721
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5722
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5722
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5723
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5723
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5724
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5724
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5725
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5725
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5726
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5726
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac ugaaagcaaa ugccaucaca accauacuaa cugccgucac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucca caugcucagc aguaucaaaa      300

ggauaucuau cggcacuuag aacuggaugg uacacaagug uuauaacuau agaacucuca      360

aacauaaaag aaaacaaaug caauggaaca gacgcaaaag uaaaacuaau aaaacaagaa      420

cucgauaaau auaaaaaugc aguaaccgaa cuacaacuau uaaugcaaag cacacccgca      480

acaggcagcg gaucagcaau agcaagcgga gucgcaguau guaaaguacu acaucuagaa      540

ggagaaguca acaaaaucaa aucugcacuu cuauccacaa acaaagcugu aguaucccua      600

uccggaugcg gagucucagu auuaacuuuu aaaguacuag accuuaaaaa cuacauagau      660

aaacaacuau uaccaauacu aaauaaacaa ucaugcagca uauccaauau agagacagua      720

auugaauuuc aacaaaaaaa caacagauua cuagaaauua cucgugaauu uuccguaaau      780

gccggaguca caacaccagu aucaaccuau augcuaacaa acagcgaacu acuuagcuua      840

auaaaugaca ugccaauaac aaaugaccaa aaaaaacuua ugucaaauaa cguacaaauc      900

gucagacaac aauccuacuc uauaaugugu auaauuaaag aagaaguccu agcauacgua      960

guucaauuac cacucuaugg aguaauagau acaccaugcu ggaaacuaca cacgucacca     1020

cuauguacaa caaacacaaa agaaggaucc aauauaugcc uaacaagaac cgacagaggc     1080

ugguauugug acaacgcagg auccguuuca uucuucccac aagcagaaac cuguaaagua     1140

caaucuaaua gaguauuuug cgacacaaug aacaguagaa cacuaccaag cgagguuaau     1200

cuauguaacg uagacauauu caauccaaaa uaugauugca aaauaaugac aucaaaaaca     1260

gauguaucgu cgaguguaau aacaagucug ggagcuauag uaagcugcua cggcaagacg     1320

aaauguaccg cuucaaauaa augcagagga aucauuaaaa cauucucgaa cggaugcgac     1380

uacguaagua auaaaggugu cgacaccgua ucaguaggga auacauuaua cuacgucaac     1440

aaacaagaag gaaaaucucu auauguaaaa ggagaaccaa uaauaaauuu cuaugacccu     1500

cuaguauucc caucagauga auuugacgcu uccauaucac aaguaaacga aaaaaucaau     1560

caaucuuuag cauucauacg aaaaagugau gaacuccuac acaacgucaa cgcaggaaaa     1620

agcacaacaa auauaaugau cacaacaauc aucauaguaa uaauaguaau acuacuauca     1680

uuaauagcag uaggauuauu gcuuuacugc aaagcacgau agggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5727
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5727
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acaauacuca ccgccguaac cuucugcuuu      240

gcgucgggac aaaacaucac cgaagaguuc uaccaaucca cuugcuccgc aguaagcaaa      300

ggauaccucu ccgcccugcg aaccgguugg uacacaucag ucaucacaau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcacc gacgcaaagg ucaaauuaau caagcaagaa      420

cuagacaaau acaaaaacgc cgucacagaa cuccagcugc uaaugcagag cacacccgca      480

acuggcagcg gauccgccau cgcaucagga gucgccgugu gcaaaguccu acaccucgaa      540

ggagaaguga acaaaaucaa aucagcccua cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gugucuccgu ccuaaccuuc aaagugcuag accucaagaa cuacaucgac      660

aaacaacucc uaccaauacu caacaagcaa ucuugcucca ucuccaacau cgaaaccgua      720

aucgaguucc aacagaagaa caaccgccuc cucgaaauca cccgcgaguu cucugucaac      780

gcagggguca ccacucccgu cuccacauac augcucacaa acuccgaacu ccucagccuc      840

aucaacgaca ugcccauaac caacgaccag aaaaagcuaa ugagcaauaa cguccaaauc      900

guuagacaac aaaguuauuc caucaugugc aucaucaaag aagaaguccu cgccuacguc      960

guacaacucc cccucuaugg cgucaucgac acccccugcu ggaaacugca cacaucaccc     1020

cucugcacca caaacaccaa agaaggcuca aacaucugcc uaacucgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cagcguauca uucuuucccc aagccgaaac augcaaaguu     1140

caauccaacc gcgucuucug cgacacaaug aacuccagaa cgcuccccag cgaagucaac     1200

cucuguaacg uagacaucuu caacccuaag uacgacugca aaaucaugac cuccaaaacu     1260

gauguauccu ccuccgucau cacaucccug ggcgccaucg ucagcugcua cggcaaaaca     1320

aaaugcacug ccucaaacaa augccgaggu aucauaaaga ccuucucaaa cggaugcgau     1380

uacgucagca acaaaggcgu cgacaccguc agugucggca acacccucua cuacgucaac     1440

aaacaagaag gaaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccagcgacga guucgacgcc uccaucucac aagucaacga aaagauaaac     1560

caaucucuag ccuucauccg caaauccgau gaacuccugc auaacgucaa cgccggcaaa     1620

uccaccacaa acaucaugau cacuaccaua aucaucguca uaaucguaau ccuccuaucu     1680

cuuaucgcag ucggccuacu acucuacugc aaagcccgcu aaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  5728
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5728
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5729
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5729
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccggug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5730
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5730
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5731
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5731
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5732
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5732
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5733
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5733
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagaug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5734
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5734
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu gaaagcaaau gccaucacaa ccauacuaac ugccgucaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaauccac augcucagca      240

guaucaaaag gauaucuauc ggcacuuaga acuggauggu acacaagugu uauaacuaua      300

gaacucucaa acauaaaaga aaacaaaugc aauggaacag acgcaaaagu aaaacuaaua      360

aaacaagaac ucgauaaaua uaaaaaugca guaaccgaac uacaacuauu aaugcaaagc      420

acacccgcaa caggcagcgg aucagcaaua gcaagcggag ucgcaguaug uaaaguacua      480

caucuagaag gagaagucaa caaaaucaaa ucugcacuuc uauccacaaa caaagcugua      540

guaucccuau ccggaugcgg agucucagua uuaacuuuua aaguacuaga ccuuaaaaac      600

uacauagaua aacaacuauu accaauacua aauaaacaau caugcagcau auccaauaua      660

gagacaguaa uugaauuuca acaaaaaaac aacagauuac uagaaauuac ucgugaauuu      720

uccguaaaug ccggagucac aacaccagua ucaaccuaua ugcuaacaaa cagcgaacua      780

cuuagcuuaa uaaaugacau gccaauaaca aaugaccaaa aaaaacuuau gucaaauaac      840

guacaaaucg ucagacaaca auccuacucu auaaugugua uaauuaaaga agaaguccua      900

gcauacguag uucaauuacc acucuaugga guaauagaua caccaugcug gaaacuacac      960

acgucaccac uauguacaac aaacacaaaa gaaggaucca auauaugccu aacaagaacc     1020

gacagaggcu gguauuguga caacgcagga uccguuucau ucuucccaca agcagaaacc     1080

uguaaaguac aaucuaauag aguauuuugc gacacaauga acaguagaac acuaccaagc     1140

gagguuaauc uauguaacgu agacauauuc aauccaaaau augauugcaa aauaaugaca     1200

ucaaaaacag auguaucguc gaguguaaua acaagucugg gagcuauagu aagcugcuac     1260

ggcaagacga aauguaccgc uucaaauaaa ugcagaggaa ucauuaaaac auucucgaac     1320

ggaugcgacu acguaaguaa uaaagguguc gacaccguau caguagggaa uacauuauac     1380

uacgucaaca aacaagaagg aaaaucucua uauguaaaag gagaaccaau aauaaauuuc     1440

uaugacccuc uaguauuccc aucagaugaa uuugacgcuu ccauaucaca aguaaacgaa     1500

aaaaucaauc aaucuuuagc auucauacga aaaagugaug aacuccuaca caacgucaac     1560

gcaggaaaaa gcacaacaaa uauaaugauc acaacaauca ucauaguaau aauaguaaua     1620

cuacuaucau uaauagcagu aggauuauug cuuuacugca aagcacgaua gggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5735
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5735
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca caauacucac cgccguaacc      180

uucugcuuug cgucgggaca aaacaucacc gaagaguucu accaauccac uugcuccgca      240

guaagcaaag gauaccucuc cgcccugcga accgguuggu acacaucagu caucacaauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcaccg acgcaaaggu caaauuaauc      360

aagcaagaac uagacaaaua caaaaacgcc gucacagaac uccagcugcu aaugcagagc      420

acacccgcaa cuggcagcgg auccgccauc gcaucaggag ucgccgugug caaaguccua      480

caccucgaag gagaagugaa caaaaucaaa ucagcccuac ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg ugucuccguc cuaaccuuca aagugcuaga ccucaagaac      600

uacaucgaca aacaacuccu accaauacuc aacaagcaau cuugcuccau cuccaacauc      660

gaaaccguaa ucgaguucca acagaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

ucugucaacg caggggucac cacucccguc uccacauaca ugcucacaaa cuccgaacuc      780

cucagccuca ucaacgacau gcccauaacc aacgaccaga aaaagcuaau gagcaauaac      840

guccaaaucg uuagacaaca aaguuauucc aucaugugca ucaucaaaga agaaguccuc      900

gccuacgucg uacaacuccc ccucuauggc gucaucgaca cccccugcug gaaacugcac      960

acaucacccc ucugcaccac aaacaccaaa gaaggcucaa acaucugccu aacucgcacc     1020

gaccgcggcu gguacugcga caacgccggc agcguaucau ucuuucccca agccgaaaca     1080

ugcaaaguuc aauccaaccg cgucuucugc gacacaauga acuccagaac gcuccccagc     1140

gaagucaacc ucuguaacgu agacaucuuc aacccuaagu acgacugcaa aaucaugacc     1200

uccaaaacug auguauccuc cuccgucauc acaucccugg gcgccaucgu cagcugcuac     1260

ggcaaaacaa aaugcacugc cucaaacaaa ugccgaggua ucauaaagac cuucucaaac     1320

ggaugcgauu acgucagcaa caaaggcguc gacaccguca gugucggcaa cacccucuac     1380

uacgucaaca aacaagaagg aaaaucccuc uacgucaaag gcgaacccau caucaacuuc     1440

uacgaccccc ucgucuuccc cagcgacgag uucgacgccu ccaucucaca agucaacgaa     1500

aagauaaacc aaucucuagc cuucauccgc aaauccgaug aacuccugca uaacgucaac     1560

gccggcaaau ccaccacaaa caucaugauc acuaccauaa ucaucgucau aaucguaauc     1620

cuccuaucuc uuaucgcagu cggccuacua cucuacugca aagcccgcua aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  5736
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5736
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5737
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5737
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccggugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5738
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5738
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5739
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5739
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5740
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5740
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5741
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5741
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagaugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5742
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5742
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacugaaa gcaaaugcca ucacaaccau acuaacugcc      120

gucacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca auccacaugc      180

ucagcaguau caaaaggaua ucuaucggca cuuagaacug gaugguacac aaguguuaua      240

acuauagaac ucucaaacau aaaagaaaac aaaugcaaug gaacagacgc aaaaguaaaa      300

cuaauaaaac aagaacucga uaaauauaaa aaugcaguaa ccgaacuaca acuauuaaug      360

caaagcacac ccgcaacagg cagcggauca gcaauagcaa gcggagucgc aguauguaaa      420

guacuacauc uagaaggaga agucaacaaa aucaaaucug cacuucuauc cacaaacaaa      480

gcuguaguau cccuauccgg augcggaguc ucaguauuaa cuuuuaaagu acuagaccuu      540

aaaaacuaca uagauaaaca acuauuacca auacuaaaua aacaaucaug cagcauaucc      600

aauauagaga caguaauuga auuucaacaa aaaaacaaca gauuacuaga aauuacucgu      660

gaauuuuccg uaaaugccgg agucacaaca ccaguaucaa ccuauaugcu aacaaacagc      720

gaacuacuua gcuuaauaaa ugacaugcca auaacaaaug accaaaaaaa acuuauguca      780

aauaacguac aaaucgucag acaacaaucc uacucuauaa uguguauaau uaaagaagaa      840

guccuagcau acguaguuca auuaccacuc uauggaguaa uagauacacc augcuggaaa      900

cuacacacgu caccacuaug uacaacaaac acaaaagaag gauccaauau augccuaaca      960

agaaccgaca gaggcuggua uugugacaac gcaggauccg uuucauucuu cccacaagca     1020

gaaaccugua aaguacaauc uaauagagua uuuugcgaca caaugaacag uagaacacua     1080

ccaagcgagg uuaaucuaug uaacguagac auauucaauc caaaauauga uugcaaaaua     1140

augacaucaa aaacagaugu aucgucgagu guaauaacaa gucugggagc uauaguaagc     1200

ugcuacggca agacgaaaug uaccgcuuca aauaaaugca gaggaaucau uaaaacauuc     1260

ucgaacggau gcgacuacgu aaguaauaaa ggugucgaca ccguaucagu agggaauaca     1320

uuauacuacg ucaacaaaca agaaggaaaa ucucuauaug uaaaaggaga accaauaaua     1380

aauuucuaug acccucuagu auucccauca gaugaauuug acgcuuccau aucacaagua     1440

aacgaaaaaa ucaaucaauc uuuagcauuc auacgaaaaa gugaugaacu ccuacacaac     1500

gucaacgcag gaaaaagcac aacaaauaua augaucacaa caaucaucau aguaauaaua     1560

guaauacuac uaucauuaau agcaguagga uuauugcuuu acugcaaagc acgauaggga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5743
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5743
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacaau acucaccgcc      120

guaaccuucu gcuuugcguc gggacaaaac aucaccgaag aguucuacca auccacuugc      180

uccgcaguaa gcaaaggaua ccucuccgcc cugcgaaccg guugguacac aucagucauc      240

acaaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcaccgacgc aaaggucaaa      300

uuaaucaagc aagaacuaga caaauacaaa aacgccguca cagaacucca gcugcuaaug      360

cagagcacac ccgcaacugg cagcggaucc gccaucgcau caggagucgc cgugugcaaa      420

guccuacacc ucgaaggaga agugaacaaa aucaaaucag cccuacucuc caccaacaag      480

gccgucgucu cccucuccgg cugcgguguc uccguccuaa ccuucaaagu gcuagaccuc      540

aagaacuaca ucgacaaaca acuccuacca auacucaaca agcaaucuug cuccaucucc      600

aacaucgaaa ccguaaucga guuccaacag aagaacaacc gccuccucga aaucacccgc      660

gaguucucug ucaacgcagg ggucaccacu cccgucucca cauacaugcu cacaaacucc      720

gaacuccuca gccucaucaa cgacaugccc auaaccaacg accagaaaaa gcuaaugagc      780

aauaacgucc aaaucguuag acaacaaagu uauuccauca ugugcaucau caaagaagaa      840

guccucgccu acgucguaca acucccccuc uauggcguca ucgacacccc cugcuggaaa      900

cugcacacau caccccucug caccacaaac accaaagaag gcucaaacau cugccuaacu      960

cgcaccgacc gcggcuggua cugcgacaac gccggcagcg uaucauucuu uccccaagcc     1020

gaaacaugca aaguucaauc caaccgcguc uucugcgaca caaugaacuc cagaacgcuc     1080

cccagcgaag ucaaccucug uaacguagac aucuucaacc cuaaguacga cugcaaaauc     1140

augaccucca aaacugaugu auccuccucc gucaucacau cccugggcgc caucgucagc     1200

ugcuacggca aaacaaaaug cacugccuca aacaaaugcc gagguaucau aaagaccuuc     1260

ucaaacggau gcgauuacgu cagcaacaaa ggcgucgaca ccgucagugu cggcaacacc     1320

cucuacuacg ucaacaaaca agaaggaaaa ucccucuacg ucaaaggcga acccaucauc     1380

aacuucuacg acccccucgu cuuccccagc gacgaguucg acgccuccau cucacaaguc     1440

aacgaaaaga uaaaccaauc ucuagccuuc auccgcaaau ccgaugaacu ccugcauaac     1500

gucaacgccg gcaaauccac cacaaacauc augaucacua ccauaaucau cgucauaauc     1560

guaauccucc uaucucuuau cgcagucggc cuacuacucu acugcaaagc ccgcuaagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  5744
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5744
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5745
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5745
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      540

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      600

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      660

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      720

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      840

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc     1080

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg     1140

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1260

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1380

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1620

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1740

agccugaucg ccguggggcu ccugcuguac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5746
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5746
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5747
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5747
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      540

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      600

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      660

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      720

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      780

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      840

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      900

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      960

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau     1020

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc     1080

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu     1140

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1200

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1260

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1320

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1380

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1440

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1500

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1560

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1620

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1680

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1740

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5748
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5748
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5749
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5749
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      540

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      600

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      660

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      720

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      780

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      840

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      900

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      960

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau     1020

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu     1080

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc     1140

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1200

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1260

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1320

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1380

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1440

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1500

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1560

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1620

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1680

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1740

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gaugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5750
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5750
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuuuuaa uacugaaagc aaaugccauc acaaccauac uaacugccgu cacauucugc      300

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau ccacaugcuc agcaguauca      360

aaaggauauc uaucggcacu uagaacugga ugguacacaa guguuauaac uauagaacuc      420

ucaaacauaa aagaaaacaa augcaaugga acagacgcaa aaguaaaacu aauaaaacaa      480

gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac uauuaaugca aagcacaccc      540

gcaacaggca gcggaucagc aauagcaagc ggagucgcag uauguaaagu acuacaucua      600

gaaggagaag ucaacaaaau caaaucugca cuucuaucca caaacaaagc uguaguaucc      660

cuauccggau gcggagucuc aguauuaacu uuuaaaguac uagaccuuaa aaacuacaua      720

gauaaacaac uauuaccaau acuaaauaaa caaucaugca gcauauccaa uauagagaca      780

guaauugaau uucaacaaaa aaacaacaga uuacuagaaa uuacucguga auuuuccgua      840

aaugccggag ucacaacacc aguaucaacc uauaugcuaa caaacagcga acuacuuagc      900

uuaauaaaug acaugccaau aacaaaugac caaaaaaaac uuaugucaaa uaacguacaa      960

aucgucagac aacaauccua cucuauaaug uguauaauua aagaagaagu ccuagcauac     1020

guaguucaau uaccacucua uggaguaaua gauacaccau gcuggaaacu acacacguca     1080

ccacuaugua caacaaacac aaaagaagga uccaauauau gccuaacaag aaccgacaga     1140

ggcugguauu gugacaacgc aggauccguu ucauucuucc cacaagcaga aaccuguaaa     1200

guacaaucua auagaguauu uugcgacaca augaacagua gaacacuacc aagcgagguu     1260

aaucuaugua acguagacau auucaaucca aaauaugauu gcaaaauaau gacaucaaaa     1320

acagauguau cgucgagugu aauaacaagu cugggagcua uaguaagcug cuacggcaag     1380

acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua aaacauucuc gaacggaugc     1440

gacuacguaa guaauaaagg ugucgacacc guaucaguag ggaauacauu auacuacguc     1500

aacaaacaag aaggaaaauc ucuauaugua aaaggagaac caauaauaaa uuucuaugac     1560

ccucuaguau ucccaucaga ugaauuugac gcuuccauau cacaaguaaa cgaaaaaauc     1620

aaucaaucuu uagcauucau acgaaaaagu gaugaacucc uacacaacgu caacgcagga     1680

aaaagcacaa caaauauaau gaucacaaca aucaucauag uaauaauagu aauacuacua     1740

ucauuaauag caguaggauu auugcuuuac ugcaaagcac gauagggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5751
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5751
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccucaaagc caacgccaua accacaauac ucaccgccgu aaccuucugc      300

uuugcgucgg gacaaaacau caccgaagag uucuaccaau ccacuugcuc cgcaguaagc      360

aaaggauacc ucuccgcccu gcgaaccggu ugguacacau cagucaucac aaucgaacuc      420

ucaaacauaa aagaaaacaa augcaacggc accgacgcaa aggucaaauu aaucaagcaa      480

gaacuagaca aauacaaaaa cgccgucaca gaacuccagc ugcuaaugca gagcacaccc      540

gcaacuggca gcggauccgc caucgcauca ggagucgccg ugugcaaagu ccuacaccuc      600

gaaggagaag ugaacaaaau caaaucagcc cuacucucca ccaacaaggc cgucgucucc      660

cucuccggcu gcggugucuc cguccuaacc uucaaagugc uagaccucaa gaacuacauc      720

gacaaacaac uccuaccaau acucaacaag caaucuugcu ccaucuccaa caucgaaacc      780

guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa ucacccgcga guucucuguc      840

aacgcagggg ucaccacucc cgucuccaca uacaugcuca caaacuccga acuccucagc      900

cucaucaacg acaugcccau aaccaacgac cagaaaaagc uaaugagcaa uaacguccaa      960

aucguuagac aacaaaguua uuccaucaug ugcaucauca aagaagaagu ccucgccuac     1020

gucguacaac ucccccucua uggcgucauc gacacccccu gcuggaaacu gcacacauca     1080

ccccucugca ccacaaacac caaagaaggc ucaaacaucu gccuaacucg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc cccaagccga aacaugcaaa     1200

guucaaucca accgcgucuu cugcgacaca augaacucca gaacgcuccc cagcgaaguc     1260

aaccucugua acguagacau cuucaacccu aaguacgacu gcaaaaucau gaccuccaaa     1320

acugauguau ccuccuccgu caucacaucc cugggcgcca ucgucagcug cuacggcaaa     1380

acaaaaugca cugccucaaa caaaugccga gguaucauaa agaccuucuc aaacggaugc     1440

gauuacguca gcaacaaagg cgucgacacc gucagugucg gcaacacccu cuacuacguc     1500

aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac ccaucaucaa cuucuacgac     1560

ccccucgucu uccccagcga cgaguucgac gccuccaucu cacaagucaa cgaaaagaua     1620

aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc ugcauaacgu caacgccggc     1680

aaauccacca caaacaucau gaucacuacc auaaucaucg ucauaaucgu aauccuccua     1740

ucucuuaucg cagucggccu acuacucuac ugcaaagccc gcuaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5752
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5752
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5753
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5753
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1080

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1200

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccguggggcu ccugcuguac ugcaaggccc ggugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5754
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5754
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5755
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5755
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      540

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      600

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      660

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      720

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      780

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau      840

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc      900

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu      960

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1020

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1080

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1140

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1200

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1260

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1320

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1440

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1500

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1560

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5756
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5756
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5757
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5757
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      540

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      600

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      660

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      720

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      780

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau      840

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu      900

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc      960

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1020

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1080

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1140

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1200

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1260

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1320

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1440

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1500

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1560

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gaugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5758
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5758
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuuuuaa uacugaaagc aaaugccauc acaaccauac uaacugccgu cacauucugc      120

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau ccacaugcuc agcaguauca      180

aaaggauauc uaucggcacu uagaacugga ugguacacaa guguuauaac uauagaacuc      240

ucaaacauaa aagaaaacaa augcaaugga acagacgcaa aaguaaaacu aauaaaacaa      300

gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac uauuaaugca aagcacaccc      360

gcaacaggca gcggaucagc aauagcaagc ggagucgcag uauguaaagu acuacaucua      420

gaaggagaag ucaacaaaau caaaucugca cuucuaucca caaacaaagc uguaguaucc      480

cuauccggau gcggagucuc aguauuaacu uuuaaaguac uagaccuuaa aaacuacaua      540

gauaaacaac uauuaccaau acuaaauaaa caaucaugca gcauauccaa uauagagaca      600

guaauugaau uucaacaaaa aaacaacaga uuacuagaaa uuacucguga auuuuccgua      660

aaugccggag ucacaacacc aguaucaacc uauaugcuaa caaacagcga acuacuuagc      720

uuaauaaaug acaugccaau aacaaaugac caaaaaaaac uuaugucaaa uaacguacaa      780

aucgucagac aacaauccua cucuauaaug uguauaauua aagaagaagu ccuagcauac      840

guaguucaau uaccacucua uggaguaaua gauacaccau gcuggaaacu acacacguca      900

ccacuaugua caacaaacac aaaagaagga uccaauauau gccuaacaag aaccgacaga      960

ggcugguauu gugacaacgc aggauccguu ucauucuucc cacaagcaga aaccuguaaa     1020

guacaaucua auagaguauu uugcgacaca augaacagua gaacacuacc aagcgagguu     1080

aaucuaugua acguagacau auucaaucca aaauaugauu gcaaaauaau gacaucaaaa     1140

acagauguau cgucgagugu aauaacaagu cugggagcua uaguaagcug cuacggcaag     1200

acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua aaacauucuc gaacggaugc     1260

gacuacguaa guaauaaagg ugucgacacc guaucaguag ggaauacauu auacuacguc     1320

aacaaacaag aaggaaaauc ucuauaugua aaaggagaac caauaauaaa uuucuaugac     1380

ccucuaguau ucccaucaga ugaauuugac gcuuccauau cacaaguaaa cgaaaaaauc     1440

aaucaaucuu uagcauucau acgaaaaagu gaugaacucc uacacaacgu caacgcagga     1500

aaaagcacaa caaauauaau gaucacaaca aucaucauag uaauaauagu aauacuacua     1560

ucauuaauag caguaggauu auugcuuuac ugcaaagcac gauagggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5759
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5759
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgccaua accacaauac ucaccgccgu aaccuucugc      120

uuugcgucgg gacaaaacau caccgaagag uucuaccaau ccacuugcuc cgcaguaagc      180

aaaggauacc ucuccgcccu gcgaaccggu ugguacacau cagucaucac aaucgaacuc      240

ucaaacauaa aagaaaacaa augcaacggc accgacgcaa aggucaaauu aaucaagcaa      300

gaacuagaca aauacaaaaa cgccgucaca gaacuccagc ugcuaaugca gagcacaccc      360

gcaacuggca gcggauccgc caucgcauca ggagucgccg ugugcaaagu ccuacaccuc      420

gaaggagaag ugaacaaaau caaaucagcc cuacucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggugucuc cguccuaacc uucaaagugc uagaccucaa gaacuacauc      540

gacaaacaac uccuaccaau acucaacaag caaucuugcu ccaucuccaa caucgaaacc      600

guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa ucacccgcga guucucuguc      660

aacgcagggg ucaccacucc cgucuccaca uacaugcuca caaacuccga acuccucagc      720

cucaucaacg acaugcccau aaccaacgac cagaaaaagc uaaugagcaa uaacguccaa      780

aucguuagac aacaaaguua uuccaucaug ugcaucauca aagaagaagu ccucgccuac      840

gucguacaac ucccccucua uggcgucauc gacacccccu gcuggaaacu gcacacauca      900

ccccucugca ccacaaacac caaagaaggc ucaaacaucu gccuaacucg caccgaccgc      960

ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc cccaagccga aacaugcaaa     1020

guucaaucca accgcgucuu cugcgacaca augaacucca gaacgcuccc cagcgaaguc     1080

aaccucugua acguagacau cuucaacccu aaguacgacu gcaaaaucau gaccuccaaa     1140

acugauguau ccuccuccgu caucacaucc cugggcgcca ucgucagcug cuacggcaaa     1200

acaaaaugca cugccucaaa caaaugccga gguaucauaa agaccuucuc aaacggaugc     1260

gauuacguca gcaacaaagg cgucgacacc gucagugucg gcaacacccu cuacuacguc     1320

aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac ccaucaucaa cuucuacgac     1380

ccccucgucu uccccagcga cgaguucgac gccuccaucu cacaagucaa cgaaaagaua     1440

aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc ugcauaacgu caacgccggc     1500

aaauccacca caaacaucau gaucacuacc auaaucaucg ucauaaucgu aauccuccua     1560

ucucuuaucg cagucggccu acuacucuac ugcaaagccc gcuaaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  5760
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5760
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5761
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5761
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5762
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5762
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5763
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5763
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5764
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5764
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5765
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5765
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5766
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5766
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacugaaagc aaaugccauc acaaccauac      120

uaacugccgu cacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

ccacaugcuc agcaguauca aaaggauauc uaucggcacu uagaacugga ugguacacaa      240

guguuauaac uauagaacuc ucaaacauaa aagaaaacaa augcaaugga acagacgcaa      300

aaguaaaacu aauaaaacaa gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac      360

uauuaaugca aagcacaccc gcaacaggca gcggaucagc aauagcaagc ggagucgcag      420

uauguaaagu acuacaucua gaaggagaag ucaacaaaau caaaucugca cuucuaucca      480

caaacaaagc uguaguaucc cuauccggau gcggagucuc aguauuaacu uuuaaaguac      540

uagaccuuaa aaacuacaua gauaaacaac uauuaccaau acuaaauaaa caaucaugca      600

gcauauccaa uauagagaca guaauugaau uucaacaaaa aaacaacaga uuacuagaaa      660

uuacucguga auuuuccgua aaugccggag ucacaacacc aguaucaacc uauaugcuaa      720

caaacagcga acuacuuagc uuaauaaaug acaugccaau aacaaaugac caaaaaaaac      780

uuaugucaaa uaacguacaa aucgucagac aacaauccua cucuauaaug uguauaauua      840

aagaagaagu ccuagcauac guaguucaau uaccacucua uggaguaaua gauacaccau      900

gcuggaaacu acacacguca ccacuaugua caacaaacac aaaagaagga uccaauauau      960

gccuaacaag aaccgacaga ggcugguauu gugacaacgc aggauccguu ucauucuucc     1020

cacaagcaga aaccuguaaa guacaaucua auagaguauu uugcgacaca augaacagua     1080

gaacacuacc aagcgagguu aaucuaugua acguagacau auucaaucca aaauaugauu     1140

gcaaaauaau gacaucaaaa acagauguau cgucgagugu aauaacaagu cugggagcua     1200

uaguaagcug cuacggcaag acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua     1260

aaacauucuc gaacggaugc gacuacguaa guaauaaagg ugucgacacc guaucaguag     1320

ggaauacauu auacuacguc aacaaacaag aaggaaaauc ucuauaugua aaaggagaac     1380

caauaauaaa uuucuaugac ccucuaguau ucccaucaga ugaauuugac gcuuccauau     1440

cacaaguaaa cgaaaaaauc aaucaaucuu uagcauucau acgaaaaagu gaugaacucc     1500

uacacaacgu caacgcagga aaaagcacaa caaauauaau gaucacaaca aucaucauag     1560

uaauaauagu aauacuacua ucauuaauag caguaggauu auugcuuuac ugcaaagcac     1620

gauagggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5767
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5767
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacaauac      120

ucaccgccgu aaccuucugc uuugcgucgg gacaaaacau caccgaagag uucuaccaau      180

ccacuugcuc cgcaguaagc aaaggauacc ucuccgcccu gcgaaccggu ugguacacau      240

cagucaucac aaucgaacuc ucaaacauaa aagaaaacaa augcaacggc accgacgcaa      300

aggucaaauu aaucaagcaa gaacuagaca aauacaaaaa cgccgucaca gaacuccagc      360

ugcuaaugca gagcacaccc gcaacuggca gcggauccgc caucgcauca ggagucgccg      420

ugugcaaagu ccuacaccuc gaaggagaag ugaacaaaau caaaucagcc cuacucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggugucuc cguccuaacc uucaaagugc      540

uagaccucaa gaacuacauc gacaaacaac uccuaccaau acucaacaag caaucuugcu      600

ccaucuccaa caucgaaacc guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucucuguc aacgcagggg ucaccacucc cgucuccaca uacaugcuca      720

caaacuccga acuccucagc cucaucaacg acaugcccau aaccaacgac cagaaaaagc      780

uaaugagcaa uaacguccaa aucguuagac aacaaaguua uuccaucaug ugcaucauca      840

aagaagaagu ccucgccuac gucguacaac ucccccucua uggcgucauc gacacccccu      900

gcuggaaacu gcacacauca ccccucugca ccacaaacac caaagaaggc ucaaacaucu      960

gccuaacucg caccgaccgc ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc     1020

cccaagccga aacaugcaaa guucaaucca accgcgucuu cugcgacaca augaacucca     1080

gaacgcuccc cagcgaaguc aaccucugua acguagacau cuucaacccu aaguacgacu     1140

gcaaaaucau gaccuccaaa acugauguau ccuccuccgu caucacaucc cugggcgcca     1200

ucgucagcug cuacggcaaa acaaaaugca cugccucaaa caaaugccga gguaucauaa     1260

agaccuucuc aaacggaugc gauuacguca gcaacaaagg cgucgacacc gucagugucg     1320

gcaacacccu cuacuacguc aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac     1380

ccaucaucaa cuucuacgac ccccucgucu uccccagcga cgaguucgac gccuccaucu     1440

cacaagucaa cgaaaagaua aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc     1500

ugcauaacgu caacgccggc aaauccacca caaacaucau gaucacuacc auaaucaucg     1560

ucauaaucgu aauccuccua ucucuuaucg cagucggccu acuacucuac ugcaaagccc     1620

gcuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5768
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5768
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5769
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5769
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5770
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5770
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5771
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5771
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5772
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5772
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5773
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5773
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5774
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5774
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacugaaagc aaaugccauc acaaccauac      120

uaacugccgu cacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

ccacaugcuc agcaguauca aaaggauauc uaucggcacu uagaacugga ugguacacaa      240

guguuauaac uauagaacuc ucaaacauaa aagaaaacaa augcaaugga acagacgcaa      300

aaguaaaacu aauaaaacaa gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac      360

uauuaaugca aagcacaccc gcaacaggca gcggaucagc aauagcaagc ggagucgcag      420

uauguaaagu acuacaucua gaaggagaag ucaacaaaau caaaucugca cuucuaucca      480

caaacaaagc uguaguaucc cuauccggau gcggagucuc aguauuaacu uuuaaaguac      540

uagaccuuaa aaacuacaua gauaaacaac uauuaccaau acuaaauaaa caaucaugca      600

gcauauccaa uauagagaca guaauugaau uucaacaaaa aaacaacaga uuacuagaaa      660

uuacucguga auuuuccgua aaugccggag ucacaacacc aguaucaacc uauaugcuaa      720

caaacagcga acuacuuagc uuaauaaaug acaugccaau aacaaaugac caaaaaaaac      780

uuaugucaaa uaacguacaa aucgucagac aacaauccua cucuauaaug uguauaauua      840

aagaagaagu ccuagcauac guaguucaau uaccacucua uggaguaaua gauacaccau      900

gcuggaaacu acacacguca ccacuaugua caacaaacac aaaagaagga uccaauauau      960

gccuaacaag aaccgacaga ggcugguauu gugacaacgc aggauccguu ucauucuucc     1020

cacaagcaga aaccuguaaa guacaaucua auagaguauu uugcgacaca augaacagua     1080

gaacacuacc aagcgagguu aaucuaugua acguagacau auucaaucca aaauaugauu     1140

gcaaaauaau gacaucaaaa acagauguau cgucgagugu aauaacaagu cugggagcua     1200

uaguaagcug cuacggcaag acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua     1260

aaacauucuc gaacggaugc gacuacguaa guaauaaagg ugucgacacc guaucaguag     1320

ggaauacauu auacuacguc aacaaacaag aaggaaaauc ucuauaugua aaaggagaac     1380

caauaauaaa uuucuaugac ccucuaguau ucccaucaga ugaauuugac gcuuccauau     1440

cacaaguaaa cgaaaaaauc aaucaaucuu uagcauucau acgaaaaagu gaugaacucc     1500

uacacaacgu caacgcagga aaaagcacaa caaauauaau gaucacaaca aucaucauag     1560

uaauaauagu aauacuacua ucauuaauag caguaggauu auugcuuuac ugcaaagcac     1620

gauagggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5775
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5775
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacaauac      120

ucaccgccgu aaccuucugc uuugcgucgg gacaaaacau caccgaagag uucuaccaau      180

ccacuugcuc cgcaguaagc aaaggauacc ucuccgcccu gcgaaccggu ugguacacau      240

cagucaucac aaucgaacuc ucaaacauaa aagaaaacaa augcaacggc accgacgcaa      300

aggucaaauu aaucaagcaa gaacuagaca aauacaaaaa cgccgucaca gaacuccagc      360

ugcuaaugca gagcacaccc gcaacuggca gcggauccgc caucgcauca ggagucgccg      420

ugugcaaagu ccuacaccuc gaaggagaag ugaacaaaau caaaucagcc cuacucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggugucuc cguccuaacc uucaaagugc      540

uagaccucaa gaacuacauc gacaaacaac uccuaccaau acucaacaag caaucuugcu      600

ccaucuccaa caucgaaacc guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucucuguc aacgcagggg ucaccacucc cgucuccaca uacaugcuca      720

caaacuccga acuccucagc cucaucaacg acaugcccau aaccaacgac cagaaaaagc      780

uaaugagcaa uaacguccaa aucguuagac aacaaaguua uuccaucaug ugcaucauca      840

aagaagaagu ccucgccuac gucguacaac ucccccucua uggcgucauc gacacccccu      900

gcuggaaacu gcacacauca ccccucugca ccacaaacac caaagaaggc ucaaacaucu      960

gccuaacucg caccgaccgc ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc     1020

cccaagccga aacaugcaaa guucaaucca accgcgucuu cugcgacaca augaacucca     1080

gaacgcuccc cagcgaaguc aaccucugua acguagacau cuucaacccu aaguacgacu     1140

gcaaaaucau gaccuccaaa acugauguau ccuccuccgu caucacaucc cugggcgcca     1200

ucgucagcug cuacggcaaa acaaaaugca cugccucaaa caaaugccga gguaucauaa     1260

agaccuucuc aaacggaugc gauuacguca gcaacaaagg cgucgacacc gucagugucg     1320

gcaacacccu cuacuacguc aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac     1380

ccaucaucaa cuucuacgac ccccucgucu uccccagcga cgaguucgac gccuccaucu     1440

cacaagucaa cgaaaagaua aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc     1500

ugcauaacgu caacgccggc aaauccacca caaacaucau gaucacuacc auaaucaucg     1560

ucauaaucgu aauccuccua ucucuuaucg cagucggccu acuacucuac ugcaaagccc     1620

gcuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  5776
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5776
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5777
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5777
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccggug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5778
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5778
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5779
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5779
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5780
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5780
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5781
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5781
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagaug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5782
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5782
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu gaaagcaaau gccaucacaa ccauacuaac ugccgucaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaauccac augcucagca      240

guaucaaaag gauaucuauc ggcacuuaga acuggauggu acacaagugu uauaacuaua      300

gaacucucaa acauaaaaga aaacaaaugc aauggaacag acgcaaaagu aaaacuaaua      360

aaacaagaac ucgauaaaua uaaaaaugca guaaccgaac uacaacuauu aaugcaaagc      420

acacccgcaa caggcagcgg aucagcaaua gcaagcggag ucgcaguaug uaaaguacua      480

caucuagaag gagaagucaa caaaaucaaa ucugcacuuc uauccacaaa caaagcugua      540

guaucccuau ccggaugcgg agucucagua uuaacuuuua aaguacuaga ccuuaaaaac      600

uacauagaua aacaacuauu accaauacua aauaaacaau caugcagcau auccaauaua      660

gagacaguaa uugaauuuca acaaaaaaac aacagauuac uagaaauuac ucgugaauuu      720

uccguaaaug ccggagucac aacaccagua ucaaccuaua ugcuaacaaa cagcgaacua      780

cuuagcuuaa uaaaugacau gccaauaaca aaugaccaaa aaaaacuuau gucaaauaac      840

guacaaaucg ucagacaaca auccuacucu auaaugugua uaauuaaaga agaaguccua      900

gcauacguag uucaauuacc acucuaugga guaauagaua caccaugcug gaaacuacac      960

acgucaccac uauguacaac aaacacaaaa gaaggaucca auauaugccu aacaagaacc     1020

gacagaggcu gguauuguga caacgcagga uccguuucau ucuucccaca agcagaaacc     1080

uguaaaguac aaucuaauag aguauuuugc gacacaauga acaguagaac acuaccaagc     1140

gagguuaauc uauguaacgu agacauauuc aauccaaaau augauugcaa aauaaugaca     1200

ucaaaaacag auguaucguc gaguguaaua acaagucugg gagcuauagu aagcugcuac     1260

ggcaagacga aauguaccgc uucaaauaaa ugcagaggaa ucauuaaaac auucucgaac     1320

ggaugcgacu acguaaguaa uaaagguguc gacaccguau caguagggaa uacauuauac     1380

uacgucaaca aacaagaagg aaaaucucua uauguaaaag gagaaccaau aauaaauuuc     1440

uaugacccuc uaguauuccc aucagaugaa uuugacgcuu ccauaucaca aguaaacgaa     1500

aaaaucaauc aaucuuuagc auucauacga aaaagugaug aacuccuaca caacgucaac     1560

gcaggaaaaa gcacaacaaa uauaaugauc acaacaauca ucauaguaau aauaguaaua     1620

cuacuaucau uaauagcagu aggauuauug cuuuacugca aagcacgaua gggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5783
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5783
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca caauacucac cgccguaacc      180

uucugcuuug cgucgggaca aaacaucacc gaagaguucu accaauccac uugcuccgca      240

guaagcaaag gauaccucuc cgcccugcga accgguuggu acacaucagu caucacaauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcaccg acgcaaaggu caaauuaauc      360

aagcaagaac uagacaaaua caaaaacgcc gucacagaac uccagcugcu aaugcagagc      420

acacccgcaa cuggcagcgg auccgccauc gcaucaggag ucgccgugug caaaguccua      480

caccucgaag gagaagugaa caaaaucaaa ucagcccuac ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg ugucuccguc cuaaccuuca aagugcuaga ccucaagaac      600

uacaucgaca aacaacuccu accaauacuc aacaagcaau cuugcuccau cuccaacauc      660

gaaaccguaa ucgaguucca acagaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

ucugucaacg caggggucac cacucccguc uccacauaca ugcucacaaa cuccgaacuc      780

cucagccuca ucaacgacau gcccauaacc aacgaccaga aaaagcuaau gagcaauaac      840

guccaaaucg uuagacaaca aaguuauucc aucaugugca ucaucaaaga agaaguccuc      900

gccuacgucg uacaacuccc ccucuauggc gucaucgaca cccccugcug gaaacugcac      960

acaucacccc ucugcaccac aaacaccaaa gaaggcucaa acaucugccu aacucgcacc     1020

gaccgcggcu gguacugcga caacgccggc agcguaucau ucuuucccca agccgaaaca     1080

ugcaaaguuc aauccaaccg cgucuucugc gacacaauga acuccagaac gcuccccagc     1140

gaagucaacc ucuguaacgu agacaucuuc aacccuaagu acgacugcaa aaucaugacc     1200

uccaaaacug auguauccuc cuccgucauc acaucccugg gcgccaucgu cagcugcuac     1260

ggcaaaacaa aaugcacugc cucaaacaaa ugccgaggua ucauaaagac cuucucaaac     1320

ggaugcgauu acgucagcaa caaaggcguc gacaccguca gugucggcaa cacccucuac     1380

uacgucaaca aacaagaagg aaaaucccuc uacgucaaag gcgaacccau caucaacuuc     1440

uacgaccccc ucgucuuccc cagcgacgag uucgacgccu ccaucucaca agucaacgaa     1500

aagauaaacc aaucucuagc cuucauccgc aaauccgaug aacuccugca uaacgucaac     1560

gccggcaaau ccaccacaaa caucaugauc acuaccauaa ucaucgucau aaucguaauc     1620

cuccuaucuc uuaucgcagu cggccuacua cucuacugca aagcccgcua aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  5784
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5784
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5785
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5785
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5786
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5786
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5787
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5787
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5788
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5788
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5789
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5789
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5790
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5790
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acugaaagca      120

aaugccauca caaccauacu aacugccguc acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc cacaugcuca gcaguaucaa aaggauaucu aucggcacuu      240

agaacuggau gguacacaag uguuauaacu auagaacucu caaacauaaa agaaaacaaa      300

ugcaauggaa cagacgcaaa aguaaaacua auaaaacaag aacucgauaa auauaaaaau      360

gcaguaaccg aacuacaacu auuaaugcaa agcacacccg caacaggcag cggaucagca      420

auagcaagcg gagucgcagu auguaaagua cuacaucuag aaggagaagu caacaaaauc      480

aaaucugcac uucuauccac aaacaaagcu guaguauccc uauccggaug cggagucuca      540

guauuaacuu uuaaaguacu agaccuuaaa aacuacauag auaaacaacu auuaccaaua      600

cuaaauaaac aaucaugcag cauauccaau auagagacag uaauugaauu ucaacaaaaa      660

aacaacagau uacuagaaau uacucgugaa uuuuccguaa augccggagu cacaacacca      720

guaucaaccu auaugcuaac aaacagcgaa cuacuuagcu uaauaaauga caugccaaua      780

acaaaugacc aaaaaaaacu uaugucaaau aacguacaaa ucgucagaca acaauccuac      840

ucuauaaugu guauaauuaa agaagaaguc cuagcauacg uaguucaauu accacucuau      900

ggaguaauag auacaccaug cuggaaacua cacacgucac cacuauguac aacaaacaca      960

aaagaaggau ccaauauaug ccuaacaaga accgacagag gcugguauug ugacaacgca     1020

ggauccguuu cauucuuccc acaagcagaa accuguaaag uacaaucuaa uagaguauuu     1080

ugcgacacaa ugaacaguag aacacuacca agcgagguua aucuauguaa cguagacaua     1140

uucaauccaa aauaugauug caaaauaaug acaucaaaaa cagauguauc gucgagugua     1200

auaacaaguc ugggagcuau aguaagcugc uacggcaaga cgaaauguac cgcuucaaau     1260

aaaugcagag gaaucauuaa aacauucucg aacggaugcg acuacguaag uaauaaaggu     1320

gucgacaccg uaucaguagg gaauacauua uacuacguca acaaacaaga aggaaaaucu     1380

cuauauguaa aaggagaacc aauaauaaau uucuaugacc cucuaguauu cccaucagau     1440

gaauuugacg cuuccauauc acaaguaaac gaaaaaauca aucaaucuuu agcauucaua     1500

cgaaaaagug augaacuccu acacaacguc aacgcaggaa aaagcacaac aaauauaaug     1560

aucacaacaa ucaucauagu aauaauagua auacuacuau cauuaauagc aguaggauua     1620

uugcuuuacu gcaaagcacg auagggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5791
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5791
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacaauacu caccgccgua accuucugcu uugcgucggg acaaaacauc      180

accgaagagu ucuaccaauc cacuugcucc gcaguaagca aaggauaccu cuccgcccug      240

cgaaccgguu gguacacauc agucaucaca aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa ggucaaauua aucaagcaag aacuagacaa auacaaaaac      360

gccgucacag aacuccagcu gcuaaugcag agcacacccg caacuggcag cggauccgcc      420

aucgcaucag gagucgccgu gugcaaaguc cuacaccucg aaggagaagu gaacaaaauc      480

aaaucagccc uacucuccac caacaaggcc gucgucuccc ucuccggcug cggugucucc      540

guccuaaccu ucaaagugcu agaccucaag aacuacaucg acaaacaacu ccuaccaaua      600

cucaacaagc aaucuugcuc caucuccaac aucgaaaccg uaaucgaguu ccaacagaag      660

aacaaccgcc uccucgaaau cacccgcgag uucucuguca acgcaggggu caccacuccc      720

gucuccacau acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugcccaua      780

accaacgacc agaaaaagcu aaugagcaau aacguccaaa ucguuagaca acaaaguuau      840

uccaucaugu gcaucaucaa agaagaaguc cucgccuacg ucguacaacu cccccucuau      900

ggcgucaucg acacccccug cuggaaacug cacacaucac cccucugcac cacaaacacc      960

aaagaaggcu caaacaucug ccuaacucgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcagcguau cauucuuucc ccaagccgaa acaugcaaag uucaauccaa ccgcgucuuc     1080

ugcgacacaa ugaacuccag aacgcucccc agcgaaguca accucuguaa cguagacauc     1140

uucaacccua aguacgacug caaaaucaug accuccaaaa cugauguauc cuccuccguc     1200

aucacauccc ugggcgccau cgucagcugc uacggcaaaa caaaaugcac ugccucaaac     1260

aaaugccgag guaucauaaa gaccuucuca aacggaugcg auuacgucag caacaaaggc     1320

gucgacaccg ucagugucgg caacacccuc uacuacguca acaaacaaga aggaaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagcgac     1440

gaguucgacg ccuccaucuc acaagucaac gaaaagauaa accaaucucu agccuucauc     1500

cgcaaauccg augaacuccu gcauaacguc aacgccggca aauccaccac aaacaucaug     1560

aucacuacca uaaucaucgu cauaaucgua auccuccuau cucuuaucgc agucggccua     1620

cuacucuacu gcaaagcccg cuaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  5792
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5792
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5793
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5793
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccggug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5794
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5794
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5795
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5795
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5796
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5796
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5797
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5797
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagaug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5798
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5798
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu gaaagcaaau gccaucacaa ccauacuaac ugccgucaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaauccac augcucagca      240

guaucaaaag gauaucuauc ggcacuuaga acuggauggu acacaagugu uauaacuaua      300

gaacucucaa acauaaaaga aaacaaaugc aauggaacag acgcaaaagu aaaacuaaua      360

aaacaagaac ucgauaaaua uaaaaaugca guaaccgaac uacaacuauu aaugcaaagc      420

acacccgcaa caggcagcgg aucagcaaua gcaagcggag ucgcaguaug uaaaguacua      480

caucuagaag gagaagucaa caaaaucaaa ucugcacuuc uauccacaaa caaagcugua      540

guaucccuau ccggaugcgg agucucagua uuaacuuuua aaguacuaga ccuuaaaaac      600

uacauagaua aacaacuauu accaauacua aauaaacaau caugcagcau auccaauaua      660

gagacaguaa uugaauuuca acaaaaaaac aacagauuac uagaaauuac ucgugaauuu      720

uccguaaaug ccggagucac aacaccagua ucaaccuaua ugcuaacaaa cagcgaacua      780

cuuagcuuaa uaaaugacau gccaauaaca aaugaccaaa aaaaacuuau gucaaauaac      840

guacaaaucg ucagacaaca auccuacucu auaaugugua uaauuaaaga agaaguccua      900

gcauacguag uucaauuacc acucuaugga guaauagaua caccaugcug gaaacuacac      960

acgucaccac uauguacaac aaacacaaaa gaaggaucca auauaugccu aacaagaacc     1020

gacagaggcu gguauuguga caacgcagga uccguuucau ucuucccaca agcagaaacc     1080

uguaaaguac aaucuaauag aguauuuugc gacacaauga acaguagaac acuaccaagc     1140

gagguuaauc uauguaacgu agacauauuc aauccaaaau augauugcaa aauaaugaca     1200

ucaaaaacag auguaucguc gaguguaaua acaagucugg gagcuauagu aagcugcuac     1260

ggcaagacga aauguaccgc uucaaauaaa ugcagaggaa ucauuaaaac auucucgaac     1320

ggaugcgacu acguaaguaa uaaagguguc gacaccguau caguagggaa uacauuauac     1380

uacgucaaca aacaagaagg aaaaucucua uauguaaaag gagaaccaau aauaaauuuc     1440

uaugacccuc uaguauuccc aucagaugaa uuugacgcuu ccauaucaca aguaaacgaa     1500

aaaaucaauc aaucuuuagc auucauacga aaaagugaug aacuccuaca caacgucaac     1560

gcaggaaaaa gcacaacaaa uauaaugauc acaacaauca ucauaguaau aauaguaaua     1620

cuacuaucau uaauagcagu aggauuauug cuuuacugca aagcacgaua gggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5799
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5799
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca caauacucac cgccguaacc      180

uucugcuuug cgucgggaca aaacaucacc gaagaguucu accaauccac uugcuccgca      240

guaagcaaag gauaccucuc cgcccugcga accgguuggu acacaucagu caucacaauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcaccg acgcaaaggu caaauuaauc      360

aagcaagaac uagacaaaua caaaaacgcc gucacagaac uccagcugcu aaugcagagc      420

acacccgcaa cuggcagcgg auccgccauc gcaucaggag ucgccgugug caaaguccua      480

caccucgaag gagaagugaa caaaaucaaa ucagcccuac ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg ugucuccguc cuaaccuuca aagugcuaga ccucaagaac      600

uacaucgaca aacaacuccu accaauacuc aacaagcaau cuugcuccau cuccaacauc      660

gaaaccguaa ucgaguucca acagaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

ucugucaacg caggggucac cacucccguc uccacauaca ugcucacaaa cuccgaacuc      780

cucagccuca ucaacgacau gcccauaacc aacgaccaga aaaagcuaau gagcaauaac      840

guccaaaucg uuagacaaca aaguuauucc aucaugugca ucaucaaaga agaaguccuc      900

gccuacgucg uacaacuccc ccucuauggc gucaucgaca cccccugcug gaaacugcac      960

acaucacccc ucugcaccac aaacaccaaa gaaggcucaa acaucugccu aacucgcacc     1020

gaccgcggcu gguacugcga caacgccggc agcguaucau ucuuucccca agccgaaaca     1080

ugcaaaguuc aauccaaccg cgucuucugc gacacaauga acuccagaac gcuccccagc     1140

gaagucaacc ucuguaacgu agacaucuuc aacccuaagu acgacugcaa aaucaugacc     1200

uccaaaacug auguauccuc cuccgucauc acaucccugg gcgccaucgu cagcugcuac     1260

ggcaaaacaa aaugcacugc cucaaacaaa ugccgaggua ucauaaagac cuucucaaac     1320

ggaugcgauu acgucagcaa caaaggcguc gacaccguca gugucggcaa cacccucuac     1380

uacgucaaca aacaagaagg aaaaucccuc uacgucaaag gcgaacccau caucaacuuc     1440

uacgaccccc ucgucuuccc cagcgacgag uucgacgccu ccaucucaca agucaacgaa     1500

aagauaaacc aaucucuagc cuucauccgc aaauccgaug aacuccugca uaacgucaac     1560

gccggcaaau ccaccacaaa caucaugauc acuaccauaa ucaucgucau aaucguaauc     1620

cuccuaucuc uuaucgcagu cggccuacua cucuacugca aagcccgcua aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  5800
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5800
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5801
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5801
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5802
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5802
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5803
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5803
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5804
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5804
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5805
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5805
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5806
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5806
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acugaaagca      120

aaugccauca caaccauacu aacugccguc acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc cacaugcuca gcaguaucaa aaggauaucu aucggcacuu      240

agaacuggau gguacacaag uguuauaacu auagaacucu caaacauaaa agaaaacaaa      300

ugcaauggaa cagacgcaaa aguaaaacua auaaaacaag aacucgauaa auauaaaaau      360

gcaguaaccg aacuacaacu auuaaugcaa agcacacccg caacaggcag cggaucagca      420

auagcaagcg gagucgcagu auguaaagua cuacaucuag aaggagaagu caacaaaauc      480

aaaucugcac uucuauccac aaacaaagcu guaguauccc uauccggaug cggagucuca      540

guauuaacuu uuaaaguacu agaccuuaaa aacuacauag auaaacaacu auuaccaaua      600

cuaaauaaac aaucaugcag cauauccaau auagagacag uaauugaauu ucaacaaaaa      660

aacaacagau uacuagaaau uacucgugaa uuuuccguaa augccggagu cacaacacca      720

guaucaaccu auaugcuaac aaacagcgaa cuacuuagcu uaauaaauga caugccaaua      780

acaaaugacc aaaaaaaacu uaugucaaau aacguacaaa ucgucagaca acaauccuac      840

ucuauaaugu guauaauuaa agaagaaguc cuagcauacg uaguucaauu accacucuau      900

ggaguaauag auacaccaug cuggaaacua cacacgucac cacuauguac aacaaacaca      960

aaagaaggau ccaauauaug ccuaacaaga accgacagag gcugguauug ugacaacgca     1020

ggauccguuu cauucuuccc acaagcagaa accuguaaag uacaaucuaa uagaguauuu     1080

ugcgacacaa ugaacaguag aacacuacca agcgagguua aucuauguaa cguagacaua     1140

uucaauccaa aauaugauug caaaauaaug acaucaaaaa cagauguauc gucgagugua     1200

auaacaaguc ugggagcuau aguaagcugc uacggcaaga cgaaauguac cgcuucaaau     1260

aaaugcagag gaaucauuaa aacauucucg aacggaugcg acuacguaag uaauaaaggu     1320

gucgacaccg uaucaguagg gaauacauua uacuacguca acaaacaaga aggaaaaucu     1380

cuauauguaa aaggagaacc aauaauaaau uucuaugacc cucuaguauu cccaucagau     1440

gaauuugacg cuuccauauc acaaguaaac gaaaaaauca aucaaucuuu agcauucaua     1500

cgaaaaagug augaacuccu acacaacguc aacgcaggaa aaagcacaac aaauauaaug     1560

aucacaacaa ucaucauagu aauaauagua auacuacuau cauuaauagc aguaggauua     1620

uugcuuuacu gcaaagcacg auagggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5807
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5807
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacaauacu caccgccgua accuucugcu uugcgucggg acaaaacauc      180

accgaagagu ucuaccaauc cacuugcucc gcaguaagca aaggauaccu cuccgcccug      240

cgaaccgguu gguacacauc agucaucaca aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa ggucaaauua aucaagcaag aacuagacaa auacaaaaac      360

gccgucacag aacuccagcu gcuaaugcag agcacacccg caacuggcag cggauccgcc      420

aucgcaucag gagucgccgu gugcaaaguc cuacaccucg aaggagaagu gaacaaaauc      480

aaaucagccc uacucuccac caacaaggcc gucgucuccc ucuccggcug cggugucucc      540

guccuaaccu ucaaagugcu agaccucaag aacuacaucg acaaacaacu ccuaccaaua      600

cucaacaagc aaucuugcuc caucuccaac aucgaaaccg uaaucgaguu ccaacagaag      660

aacaaccgcc uccucgaaau cacccgcgag uucucuguca acgcaggggu caccacuccc      720

gucuccacau acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugcccaua      780

accaacgacc agaaaaagcu aaugagcaau aacguccaaa ucguuagaca acaaaguuau      840

uccaucaugu gcaucaucaa agaagaaguc cucgccuacg ucguacaacu cccccucuau      900

ggcgucaucg acacccccug cuggaaacug cacacaucac cccucugcac cacaaacacc      960

aaagaaggcu caaacaucug ccuaacucgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcagcguau cauucuuucc ccaagccgaa acaugcaaag uucaauccaa ccgcgucuuc     1080

ugcgacacaa ugaacuccag aacgcucccc agcgaaguca accucuguaa cguagacauc     1140

uucaacccua aguacgacug caaaaucaug accuccaaaa cugauguauc cuccuccguc     1200

aucacauccc ugggcgccau cgucagcugc uacggcaaaa caaaaugcac ugccucaaac     1260

aaaugccgag guaucauaaa gaccuucuca aacggaugcg auuacgucag caacaaaggc     1320

gucgacaccg ucagugucgg caacacccuc uacuacguca acaaacaaga aggaaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagcgac     1440

gaguucgacg ccuccaucuc acaagucaac gaaaagauaa accaaucucu agccuucauc     1500

cgcaaauccg augaacuccu gcauaacguc aacgccggca aauccaccac aaacaucaug     1560

aucacuacca uaaucaucgu cauaaucgua auccuccuau cucuuaucgc agucggccua     1620

cuacucuacu gcaaagcccg cuaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  5808
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5808
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5809
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5809
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5810
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5810
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5811
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5811
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5812
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5812
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5813
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5813
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5814
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5814
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acugaaagca      120

aaugccauca caaccauacu aacugccguc acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc cacaugcuca gcaguaucaa aaggauaucu aucggcacuu      240

agaacuggau gguacacaag uguuauaacu auagaacucu caaacauaaa agaaaacaaa      300

ugcaauggaa cagacgcaaa aguaaaacua auaaaacaag aacucgauaa auauaaaaau      360

gcaguaaccg aacuacaacu auuaaugcaa agcacacccg caacaggcag cggaucagca      420

auagcaagcg gagucgcagu auguaaagua cuacaucuag aaggagaagu caacaaaauc      480

aaaucugcac uucuauccac aaacaaagcu guaguauccc uauccggaug cggagucuca      540

guauuaacuu uuaaaguacu agaccuuaaa aacuacauag auaaacaacu auuaccaaua      600

cuaaauaaac aaucaugcag cauauccaau auagagacag uaauugaauu ucaacaaaaa      660

aacaacagau uacuagaaau uacucgugaa uuuuccguaa augccggagu cacaacacca      720

guaucaaccu auaugcuaac aaacagcgaa cuacuuagcu uaauaaauga caugccaaua      780

acaaaugacc aaaaaaaacu uaugucaaau aacguacaaa ucgucagaca acaauccuac      840

ucuauaaugu guauaauuaa agaagaaguc cuagcauacg uaguucaauu accacucuau      900

ggaguaauag auacaccaug cuggaaacua cacacgucac cacuauguac aacaaacaca      960

aaagaaggau ccaauauaug ccuaacaaga accgacagag gcugguauug ugacaacgca     1020

ggauccguuu cauucuuccc acaagcagaa accuguaaag uacaaucuaa uagaguauuu     1080

ugcgacacaa ugaacaguag aacacuacca agcgagguua aucuauguaa cguagacaua     1140

uucaauccaa aauaugauug caaaauaaug acaucaaaaa cagauguauc gucgagugua     1200

auaacaaguc ugggagcuau aguaagcugc uacggcaaga cgaaauguac cgcuucaaau     1260

aaaugcagag gaaucauuaa aacauucucg aacggaugcg acuacguaag uaauaaaggu     1320

gucgacaccg uaucaguagg gaauacauua uacuacguca acaaacaaga aggaaaaucu     1380

cuauauguaa aaggagaacc aauaauaaau uucuaugacc cucuaguauu cccaucagau     1440

gaauuugacg cuuccauauc acaaguaaac gaaaaaauca aucaaucuuu agcauucaua     1500

cgaaaaagug augaacuccu acacaacguc aacgcaggaa aaagcacaac aaauauaaug     1560

aucacaacaa ucaucauagu aauaauagua auacuacuau cauuaauagc aguaggauua     1620

uugcuuuacu gcaaagcacg auagggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5815
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5815
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacaauacu caccgccgua accuucugcu uugcgucggg acaaaacauc      180

accgaagagu ucuaccaauc cacuugcucc gcaguaagca aaggauaccu cuccgcccug      240

cgaaccgguu gguacacauc agucaucaca aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa ggucaaauua aucaagcaag aacuagacaa auacaaaaac      360

gccgucacag aacuccagcu gcuaaugcag agcacacccg caacuggcag cggauccgcc      420

aucgcaucag gagucgccgu gugcaaaguc cuacaccucg aaggagaagu gaacaaaauc      480

aaaucagccc uacucuccac caacaaggcc gucgucuccc ucuccggcug cggugucucc      540

guccuaaccu ucaaagugcu agaccucaag aacuacaucg acaaacaacu ccuaccaaua      600

cucaacaagc aaucuugcuc caucuccaac aucgaaaccg uaaucgaguu ccaacagaag      660

aacaaccgcc uccucgaaau cacccgcgag uucucuguca acgcaggggu caccacuccc      720

gucuccacau acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugcccaua      780

accaacgacc agaaaaagcu aaugagcaau aacguccaaa ucguuagaca acaaaguuau      840

uccaucaugu gcaucaucaa agaagaaguc cucgccuacg ucguacaacu cccccucuau      900

ggcgucaucg acacccccug cuggaaacug cacacaucac cccucugcac cacaaacacc      960

aaagaaggcu caaacaucug ccuaacucgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcagcguau cauucuuucc ccaagccgaa acaugcaaag uucaauccaa ccgcgucuuc     1080

ugcgacacaa ugaacuccag aacgcucccc agcgaaguca accucuguaa cguagacauc     1140

uucaacccua aguacgacug caaaaucaug accuccaaaa cugauguauc cuccuccguc     1200

aucacauccc ugggcgccau cgucagcugc uacggcaaaa caaaaugcac ugccucaaac     1260

aaaugccgag guaucauaaa gaccuucuca aacggaugcg auuacgucag caacaaaggc     1320

gucgacaccg ucagugucgg caacacccuc uacuacguca acaaacaaga aggaaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagcgac     1440

gaguucgacg ccuccaucuc acaagucaac gaaaagauaa accaaucucu agccuucauc     1500

cgcaaauccg augaacuccu gcauaacguc aacgccggca aauccaccac aaacaucaug     1560

aucacuacca uaaucaucgu cauaaucgua auccuccuau cucuuaucgc agucggccua     1620

cuacucuacu gcaaagcccg cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  5816
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5816
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5817
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5817
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5818
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5818
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5819
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5819
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5820
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5820
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5821
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5821
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagaugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5822
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5822
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacugaa agcaaaugcc      120

aucacaacca uacuaacugc cgucacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aauccacaug cucagcagua ucaaaaggau aucuaucggc acuuagaacu      240

ggaugguaca caaguguuau aacuauagaa cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacagacg caaaaguaaa acuaauaaaa caagaacucg auaaauauaa aaaugcagua      360

accgaacuac aacuauuaau gcaaagcaca cccgcaacag gcagcggauc agcaauagca      420

agcggagucg caguauguaa aguacuacau cuagaaggag aagucaacaa aaucaaaucu      480

gcacuucuau ccacaaacaa agcuguagua ucccuauccg gaugcggagu cucaguauua      540

acuuuuaaag uacuagaccu uaaaaacuac auagauaaac aacuauuacc aauacuaaau      600

aaacaaucau gcagcauauc caauauagag acaguaauug aauuucaaca aaaaaacaac      660

agauuacuag aaauuacucg ugaauuuucc guaaaugccg gagucacaac accaguauca      720

accuauaugc uaacaaacag cgaacuacuu agcuuaauaa augacaugcc aauaacaaau      780

gaccaaaaaa aacuuauguc aaauaacgua caaaucguca gacaacaauc cuacucuaua      840

auguguauaa uuaaagaaga aguccuagca uacguaguuc aauuaccacu cuauggagua      900

auagauacac caugcuggaa acuacacacg ucaccacuau guacaacaaa cacaaaagaa      960

ggauccaaua uaugccuaac aagaaccgac agaggcuggu auugugacaa cgcaggaucc     1020

guuucauucu ucccacaagc agaaaccugu aaaguacaau cuaauagagu auuuugcgac     1080

acaaugaaca guagaacacu accaagcgag guuaaucuau guaacguaga cauauucaau     1140

ccaaaauaug auugcaaaau aaugacauca aaaacagaug uaucgucgag uguaauaaca     1200

agucugggag cuauaguaag cugcuacggc aagacgaaau guaccgcuuc aaauaaaugc     1260

agaggaauca uuaaaacauu cucgaacgga ugcgacuacg uaaguaauaa aggugucgac     1320

accguaucag uagggaauac auuauacuac gucaacaaac aagaaggaaa aucucuauau     1380

guaaaaggag aaccaauaau aaauuucuau gacccucuag uauucccauc agaugaauuu     1440

gacgcuucca uaucacaagu aaacgaaaaa aucaaucaau cuuuagcauu cauacgaaaa     1500

agugaugaac uccuacacaa cgucaacgca ggaaaaagca caacaaauau aaugaucaca     1560

acaaucauca uaguaauaau aguaauacua cuaucauuaa uagcaguagg auuauugcuu     1620

uacugcaaag cacgauaggg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5823
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5823
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacaa uacucaccgc cguaaccuuc ugcuuugcgu cgggacaaaa caucaccgaa      180

gaguucuacc aauccacuug cuccgcagua agcaaaggau accucuccgc ccugcgaacc      240

gguugguaca caucagucau cacaaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaggucaa auuaaucaag caagaacuag acaaauacaa aaacgccguc      360

acagaacucc agcugcuaau gcagagcaca cccgcaacug gcagcggauc cgccaucgca      420

ucaggagucg ccgugugcaa aguccuacac cucgaaggag aagugaacaa aaucaaauca      480

gcccuacucu ccaccaacaa ggccgucguc ucccucuccg gcugcggugu cuccguccua      540

accuucaaag ugcuagaccu caagaacuac aucgacaaac aacuccuacc aauacucaac      600

aagcaaucuu gcuccaucuc caacaucgaa accguaaucg aguuccaaca gaagaacaac      660

cgccuccucg aaaucacccg cgaguucucu gucaacgcag gggucaccac ucccgucucc      720

acauacaugc ucacaaacuc cgaacuccuc agccucauca acgacaugcc cauaaccaac      780

gaccagaaaa agcuaaugag caauaacguc caaaucguua gacaacaaag uuauuccauc      840

augugcauca ucaaagaaga aguccucgcc uacgucguac aacucccccu cuauggcguc      900

aucgacaccc ccugcuggaa acugcacaca ucaccccucu gcaccacaaa caccaaagaa      960

ggcucaaaca ucugccuaac ucgcaccgac cgcggcuggu acugcgacaa cgccggcagc     1020

guaucauucu uuccccaagc cgaaacaugc aaaguucaau ccaaccgcgu cuucugcgac     1080

acaaugaacu ccagaacgcu ccccagcgaa gucaaccucu guaacguaga caucuucaac     1140

ccuaaguacg acugcaaaau caugaccucc aaaacugaug uauccuccuc cgucaucaca     1200

ucccugggcg ccaucgucag cugcuacggc aaaacaaaau gcacugccuc aaacaaaugc     1260

cgagguauca uaaagaccuu cucaaacgga ugcgauuacg ucagcaacaa aggcgucgac     1320

accgucagug ucggcaacac ccucuacuac gucaacaaac aagaaggaaa aucccucuac     1380

gucaaaggcg aacccaucau caacuucuac gacccccucg ucuuccccag cgacgaguuc     1440

gacgccucca ucucacaagu caacgaaaag auaaaccaau cucuagccuu cauccgcaaa     1500

uccgaugaac uccugcauaa cgucaacgcc ggcaaaucca ccacaaacau caugaucacu     1560

accauaauca ucgucauaau cguaauccuc cuaucucuua ucgcagucgg ccuacuacuc     1620

uacugcaaag cccgcuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  5824
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5824
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5825
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5825
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccggugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5826
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5826
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5827
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5827
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5828
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5828
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5829
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5829
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagaugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5830
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5830
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacugaaa      120

gcaaaugcca ucacaaccau acuaacugcc gucacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca auccacaugc ucagcaguau caaaaggaua ucuaucggca      240

cuuagaacug gaugguacac aaguguuaua acuauagaac ucucaaacau aaaagaaaac      300

aaaugcaaug gaacagacgc aaaaguaaaa cuaauaaaac aagaacucga uaaauauaaa      360

aaugcaguaa ccgaacuaca acuauuaaug caaagcacac ccgcaacagg cagcggauca      420

gcaauagcaa gcggagucgc aguauguaaa guacuacauc uagaaggaga agucaacaaa      480

aucaaaucug cacuucuauc cacaaacaaa gcuguaguau cccuauccgg augcggaguc      540

ucaguauuaa cuuuuaaagu acuagaccuu aaaaacuaca uagauaaaca acuauuacca      600

auacuaaaua aacaaucaug cagcauaucc aauauagaga caguaauuga auuucaacaa      660

aaaaacaaca gauuacuaga aauuacucgu gaauuuuccg uaaaugccgg agucacaaca      720

ccaguaucaa ccuauaugcu aacaaacagc gaacuacuua gcuuaauaaa ugacaugcca      780

auaacaaaug accaaaaaaa acuuauguca aauaacguac aaaucgucag acaacaaucc      840

uacucuauaa uguguauaau uaaagaagaa guccuagcau acguaguuca auuaccacuc      900

uauggaguaa uagauacacc augcuggaaa cuacacacgu caccacuaug uacaacaaac      960

acaaaagaag gauccaauau augccuaaca agaaccgaca gaggcuggua uugugacaac     1020

gcaggauccg uuucauucuu cccacaagca gaaaccugua aaguacaauc uaauagagua     1080

uuuugcgaca caaugaacag uagaacacua ccaagcgagg uuaaucuaug uaacguagac     1140

auauucaauc caaaauauga uugcaaaaua augacaucaa aaacagaugu aucgucgagu     1200

guaauaacaa gucugggagc uauaguaagc ugcuacggca agacgaaaug uaccgcuuca     1260

aauaaaugca gaggaaucau uaaaacauuc ucgaacggau gcgacuacgu aaguaauaaa     1320

ggugucgaca ccguaucagu agggaauaca uuauacuacg ucaacaaaca agaaggaaaa     1380

ucucuauaug uaaaaggaga accaauaaua aauuucuaug acccucuagu auucccauca     1440

gaugaauuug acgcuuccau aucacaagua aacgaaaaaa ucaaucaauc uuuagcauuc     1500

auacgaaaaa gugaugaacu ccuacacaac gucaacgcag gaaaaagcac aacaaauaua     1560

augaucacaa caaucaucau aguaauaaua guaauacuac uaucauuaau agcaguagga     1620

uuauugcuuu acugcaaagc acgauaggga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5831
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5831
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacaau acucaccgcc guaaccuucu gcuuugcguc gggacaaaac      180

aucaccgaag aguucuacca auccacuugc uccgcaguaa gcaaaggaua ccucuccgcc      240

cugcgaaccg guugguacac aucagucauc acaaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaggucaaa uuaaucaagc aagaacuaga caaauacaaa      360

aacgccguca cagaacucca gcugcuaaug cagagcacac ccgcaacugg cagcggaucc      420

gccaucgcau caggagucgc cgugugcaaa guccuacacc ucgaaggaga agugaacaaa      480

aucaaaucag cccuacucuc caccaacaag gccgucgucu cccucuccgg cugcgguguc      540

uccguccuaa ccuucaaagu gcuagaccuc aagaacuaca ucgacaaaca acuccuacca      600

auacucaaca agcaaucuug cuccaucucc aacaucgaaa ccguaaucga guuccaacag      660

aagaacaacc gccuccucga aaucacccgc gaguucucug ucaacgcagg ggucaccacu      720

cccgucucca cauacaugcu cacaaacucc gaacuccuca gccucaucaa cgacaugccc      780

auaaccaacg accagaaaaa gcuaaugagc aauaacgucc aaaucguuag acaacaaagu      840

uauuccauca ugugcaucau caaagaagaa guccucgccu acgucguaca acucccccuc      900

uauggcguca ucgacacccc cugcuggaaa cugcacacau caccccucug caccacaaac      960

accaaagaag gcucaaacau cugccuaacu cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcagcg uaucauucuu uccccaagcc gaaacaugca aaguucaauc caaccgcguc     1080

uucugcgaca caaugaacuc cagaacgcuc cccagcgaag ucaaccucug uaacguagac     1140

aucuucaacc cuaaguacga cugcaaaauc augaccucca aaacugaugu auccuccucc     1200

gucaucacau cccugggcgc caucgucagc ugcuacggca aaacaaaaug cacugccuca     1260

aacaaaugcc gagguaucau aaagaccuuc ucaaacggau gcgauuacgu cagcaacaaa     1320

ggcgucgaca ccgucagugu cggcaacacc cucuacuacg ucaacaaaca agaaggaaaa     1380

ucccucuacg ucaaaggcga acccaucauc aacuucuacg acccccucgu cuuccccagc     1440

gacgaguucg acgccuccau cucacaaguc aacgaaaaga uaaaccaauc ucuagccuuc     1500

auccgcaaau ccgaugaacu ccugcauaac gucaacgccg gcaaauccac cacaaacauc     1560

augaucacua ccauaaucau cgucauaauc guaauccucc uaucucuuau cgcagucggc     1620

cuacuacucu acugcaaagc ccgcuaagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  5832
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5832
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5833
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5833
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5834
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5834
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5835
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5835
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5836
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5836
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5837
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5837
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagaugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5838
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5838
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacugaa agcaaaugcc      120

aucacaacca uacuaacugc cgucacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aauccacaug cucagcagua ucaaaaggau aucuaucggc acuuagaacu      240

ggaugguaca caaguguuau aacuauagaa cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacagacg caaaaguaaa acuaauaaaa caagaacucg auaaauauaa aaaugcagua      360

accgaacuac aacuauuaau gcaaagcaca cccgcaacag gcagcggauc agcaauagca      420

agcggagucg caguauguaa aguacuacau cuagaaggag aagucaacaa aaucaaaucu      480

gcacuucuau ccacaaacaa agcuguagua ucccuauccg gaugcggagu cucaguauua      540

acuuuuaaag uacuagaccu uaaaaacuac auagauaaac aacuauuacc aauacuaaau      600

aaacaaucau gcagcauauc caauauagag acaguaauug aauuucaaca aaaaaacaac      660

agauuacuag aaauuacucg ugaauuuucc guaaaugccg gagucacaac accaguauca      720

accuauaugc uaacaaacag cgaacuacuu agcuuaauaa augacaugcc aauaacaaau      780

gaccaaaaaa aacuuauguc aaauaacgua caaaucguca gacaacaauc cuacucuaua      840

auguguauaa uuaaagaaga aguccuagca uacguaguuc aauuaccacu cuauggagua      900

auagauacac caugcuggaa acuacacacg ucaccacuau guacaacaaa cacaaaagaa      960

ggauccaaua uaugccuaac aagaaccgac agaggcuggu auugugacaa cgcaggaucc     1020

guuucauucu ucccacaagc agaaaccugu aaaguacaau cuaauagagu auuuugcgac     1080

acaaugaaca guagaacacu accaagcgag guuaaucuau guaacguaga cauauucaau     1140

ccaaaauaug auugcaaaau aaugacauca aaaacagaug uaucgucgag uguaauaaca     1200

agucugggag cuauaguaag cugcuacggc aagacgaaau guaccgcuuc aaauaaaugc     1260

agaggaauca uuaaaacauu cucgaacgga ugcgacuacg uaaguaauaa aggugucgac     1320

accguaucag uagggaauac auuauacuac gucaacaaac aagaaggaaa aucucuauau     1380

guaaaaggag aaccaauaau aaauuucuau gacccucuag uauucccauc agaugaauuu     1440

gacgcuucca uaucacaagu aaacgaaaaa aucaaucaau cuuuagcauu cauacgaaaa     1500

agugaugaac uccuacacaa cgucaacgca ggaaaaagca caacaaauau aaugaucaca     1560

acaaucauca uaguaauaau aguaauacua cuaucauuaa uagcaguagg auuauugcuu     1620

uacugcaaag cacgauaggg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5839
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5839
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacaa uacucaccgc cguaaccuuc ugcuuugcgu cgggacaaaa caucaccgaa      180

gaguucuacc aauccacuug cuccgcagua agcaaaggau accucuccgc ccugcgaacc      240

gguugguaca caucagucau cacaaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaggucaa auuaaucaag caagaacuag acaaauacaa aaacgccguc      360

acagaacucc agcugcuaau gcagagcaca cccgcaacug gcagcggauc cgccaucgca      420

ucaggagucg ccgugugcaa aguccuacac cucgaaggag aagugaacaa aaucaaauca      480

gcccuacucu ccaccaacaa ggccgucguc ucccucuccg gcugcggugu cuccguccua      540

accuucaaag ugcuagaccu caagaacuac aucgacaaac aacuccuacc aauacucaac      600

aagcaaucuu gcuccaucuc caacaucgaa accguaaucg aguuccaaca gaagaacaac      660

cgccuccucg aaaucacccg cgaguucucu gucaacgcag gggucaccac ucccgucucc      720

acauacaugc ucacaaacuc cgaacuccuc agccucauca acgacaugcc cauaaccaac      780

gaccagaaaa agcuaaugag caauaacguc caaaucguua gacaacaaag uuauuccauc      840

augugcauca ucaaagaaga aguccucgcc uacgucguac aacucccccu cuauggcguc      900

aucgacaccc ccugcuggaa acugcacaca ucaccccucu gcaccacaaa caccaaagaa      960

ggcucaaaca ucugccuaac ucgcaccgac cgcggcuggu acugcgacaa cgccggcagc     1020

guaucauucu uuccccaagc cgaaacaugc aaaguucaau ccaaccgcgu cuucugcgac     1080

acaaugaacu ccagaacgcu ccccagcgaa gucaaccucu guaacguaga caucuucaac     1140

ccuaaguacg acugcaaaau caugaccucc aaaacugaug uauccuccuc cgucaucaca     1200

ucccugggcg ccaucgucag cugcuacggc aaaacaaaau gcacugccuc aaacaaaugc     1260

cgagguauca uaaagaccuu cucaaacgga ugcgauuacg ucagcaacaa aggcgucgac     1320

accgucagug ucggcaacac ccucuacuac gucaacaaac aagaaggaaa aucccucuac     1380

gucaaaggcg aacccaucau caacuucuac gacccccucg ucuuccccag cgacgaguuc     1440

gacgccucca ucucacaagu caacgaaaag auaaaccaau cucuagccuu cauccgcaaa     1500

uccgaugaac uccugcauaa cgucaacgcc ggcaaaucca ccacaaacau caugaucacu     1560

accauaauca ucgucauaau cguaauccuc cuaucucuua ucgcagucgg ccuacuacuc     1620

uacugcaaag cccgcuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  5840
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5840
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5841
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5841
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5842
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5842
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5843
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5843
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5844
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5844
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5845
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5845
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5846
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5846
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac ugaaagcaaa ugccaucaca accauacuaa cugccgucac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucca caugcucagc aguaucaaaa      300

ggauaucuau cggcacuuag aacuggaugg uacacaagug uuauaacuau agaacucuca      360

aacauaaaag aaaacaaaug caauggaaca gacgcaaaag uaaaacuaau aaaacaagaa      420

cucgauaaau auaaaaaugc aguaaccgaa cuacaacuau uaaugcaaag cacacccgca      480

acaggcagcg gaucagcaau agcaagcgga gucgcaguau guaaaguacu acaucuagaa      540

ggagaaguca acaaaaucaa aucugcacuu cuauccacaa acaaagcugu aguaucccua      600

uccggaugcg gagucucagu auuaacuuuu aaaguacuag accuuaaaaa cuacauagau      660

aaacaacuau uaccaauacu aaauaaacaa ucaugcagca uauccaauau agagacagua      720

auugaauuuc aacaaaaaaa caacagauua cuagaaauua cucgugaauu uuccguaaau      780

gccggaguca caacaccagu aucaaccuau augcuaacaa acagcgaacu acuuagcuua      840

auaaaugaca ugccaauaac aaaugaccaa aaaaaacuua ugucaaauaa cguacaaauc      900

gucagacaac aauccuacuc uauaaugugu auaauuaaag aagaaguccu agcauacgua      960

guucaauuac cacucuaugg aguaauagau acaccaugcu ggaaacuaca cacgucacca     1020

cuauguacaa caaacacaaa agaaggaucc aauauaugcc uaacaagaac cgacagaggc     1080

ugguauugug acaacgcagg auccguuuca uucuucccac aagcagaaac cuguaaagua     1140

caaucuaaua gaguauuuug cgacacaaug aacaguagaa cacuaccaag cgagguuaau     1200

cuauguaacg uagacauauu caauccaaaa uaugauugca aaauaaugac aucaaaaaca     1260

gauguaucgu cgaguguaau aacaagucug ggagcuauag uaagcugcua cggcaagacg     1320

aaauguaccg cuucaaauaa augcagagga aucauuaaaa cauucucgaa cggaugcgac     1380

uacguaagua auaaaggugu cgacaccgua ucaguaggga auacauuaua cuacgucaac     1440

aaacaagaag gaaaaucucu auauguaaaa ggagaaccaa uaauaaauuu cuaugacccu     1500

cuaguauucc caucagauga auuugacgcu uccauaucac aaguaaacga aaaaaucaau     1560

caaucuuuag cauucauacg aaaaagugau gaacuccuac acaacgucaa cgcaggaaaa     1620

agcacaacaa auauaaugau cacaacaauc aucauaguaa uaauaguaau acuacuauca     1680

uuaauagcag uaggauuauu gcuuuacugc aaagcacgau agggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5847
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5847
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acaauacuca ccgccguaac cuucugcuuu      240

gcgucgggac aaaacaucac cgaagaguuc uaccaaucca cuugcuccgc aguaagcaaa      300

ggauaccucu ccgcccugcg aaccgguugg uacacaucag ucaucacaau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcacc gacgcaaagg ucaaauuaau caagcaagaa      420

cuagacaaau acaaaaacgc cgucacagaa cuccagcugc uaaugcagag cacacccgca      480

acuggcagcg gauccgccau cgcaucagga gucgccgugu gcaaaguccu acaccucgaa      540

ggagaaguga acaaaaucaa aucagcccua cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gugucuccgu ccuaaccuuc aaagugcuag accucaagaa cuacaucgac      660

aaacaacucc uaccaauacu caacaagcaa ucuugcucca ucuccaacau cgaaaccgua      720

aucgaguucc aacagaagaa caaccgccuc cucgaaauca cccgcgaguu cucugucaac      780

gcagggguca ccacucccgu cuccacauac augcucacaa acuccgaacu ccucagccuc      840

aucaacgaca ugcccauaac caacgaccag aaaaagcuaa ugagcaauaa cguccaaauc      900

guuagacaac aaaguuauuc caucaugugc aucaucaaag aagaaguccu cgccuacguc      960

guacaacucc cccucuaugg cgucaucgac acccccugcu ggaaacugca cacaucaccc     1020

cucugcacca caaacaccaa agaaggcuca aacaucugcc uaacucgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cagcguauca uucuuucccc aagccgaaac augcaaaguu     1140

caauccaacc gcgucuucug cgacacaaug aacuccagaa cgcuccccag cgaagucaac     1200

cucuguaacg uagacaucuu caacccuaag uacgacugca aaaucaugac cuccaaaacu     1260

gauguauccu ccuccgucau cacaucccug ggcgccaucg ucagcugcua cggcaaaaca     1320

aaaugcacug ccucaaacaa augccgaggu aucauaaaga ccuucucaaa cggaugcgau     1380

uacgucagca acaaaggcgu cgacaccguc agugucggca acacccucua cuacgucaac     1440

aaacaagaag gaaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccagcgacga guucgacgcc uccaucucac aagucaacga aaagauaaac     1560

caaucucuag ccuucauccg caaauccgau gaacuccugc auaacgucaa cgccggcaaa     1620

uccaccacaa acaucaugau cacuaccaua aucaucguca uaaucguaau ccuccuaucu     1680

cuuaucgcag ucggccuacu acucuacugc aaagcccgcu aaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5848
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5848
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5849
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5849
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5850
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5850
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5851
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5851
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5852
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5852
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5853
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5853
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5854
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5854
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacugaaagc aaaugccauc acaaccauac      120

uaacugccgu cacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

ccacaugcuc agcaguauca aaaggauauc uaucggcacu uagaacugga ugguacacaa      240

guguuauaac uauagaacuc ucaaacauaa aagaaaacaa augcaaugga acagacgcaa      300

aaguaaaacu aauaaaacaa gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac      360

uauuaaugca aagcacaccc gcaacaggca gcggaucagc aauagcaagc ggagucgcag      420

uauguaaagu acuacaucua gaaggagaag ucaacaaaau caaaucugca cuucuaucca      480

caaacaaagc uguaguaucc cuauccggau gcggagucuc aguauuaacu uuuaaaguac      540

uagaccuuaa aaacuacaua gauaaacaac uauuaccaau acuaaauaaa caaucaugca      600

gcauauccaa uauagagaca guaauugaau uucaacaaaa aaacaacaga uuacuagaaa      660

uuacucguga auuuuccgua aaugccggag ucacaacacc aguaucaacc uauaugcuaa      720

caaacagcga acuacuuagc uuaauaaaug acaugccaau aacaaaugac caaaaaaaac      780

uuaugucaaa uaacguacaa aucgucagac aacaauccua cucuauaaug uguauaauua      840

aagaagaagu ccuagcauac guaguucaau uaccacucua uggaguaaua gauacaccau      900

gcuggaaacu acacacguca ccacuaugua caacaaacac aaaagaagga uccaauauau      960

gccuaacaag aaccgacaga ggcugguauu gugacaacgc aggauccguu ucauucuucc     1020

cacaagcaga aaccuguaaa guacaaucua auagaguauu uugcgacaca augaacagua     1080

gaacacuacc aagcgagguu aaucuaugua acguagacau auucaaucca aaauaugauu     1140

gcaaaauaau gacaucaaaa acagauguau cgucgagugu aauaacaagu cugggagcua     1200

uaguaagcug cuacggcaag acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua     1260

aaacauucuc gaacggaugc gacuacguaa guaauaaagg ugucgacacc guaucaguag     1320

ggaauacauu auacuacguc aacaaacaag aaggaaaauc ucuauaugua aaaggagaac     1380

caauaauaaa uuucuaugac ccucuaguau ucccaucaga ugaauuugac gcuuccauau     1440

cacaaguaaa cgaaaaaauc aaucaaucuu uagcauucau acgaaaaagu gaugaacucc     1500

uacacaacgu caacgcagga aaaagcacaa caaauauaau gaucacaaca aucaucauag     1560

uaauaauagu aauacuacua ucauuaauag caguaggauu auugcuuuac ugcaaagcac     1620

gauagggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5855
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5855
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacaauac      120

ucaccgccgu aaccuucugc uuugcgucgg gacaaaacau caccgaagag uucuaccaau      180

ccacuugcuc cgcaguaagc aaaggauacc ucuccgcccu gcgaaccggu ugguacacau      240

cagucaucac aaucgaacuc ucaaacauaa aagaaaacaa augcaacggc accgacgcaa      300

aggucaaauu aaucaagcaa gaacuagaca aauacaaaaa cgccgucaca gaacuccagc      360

ugcuaaugca gagcacaccc gcaacuggca gcggauccgc caucgcauca ggagucgccg      420

ugugcaaagu ccuacaccuc gaaggagaag ugaacaaaau caaaucagcc cuacucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggugucuc cguccuaacc uucaaagugc      540

uagaccucaa gaacuacauc gacaaacaac uccuaccaau acucaacaag caaucuugcu      600

ccaucuccaa caucgaaacc guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucucuguc aacgcagggg ucaccacucc cgucuccaca uacaugcuca      720

caaacuccga acuccucagc cucaucaacg acaugcccau aaccaacgac cagaaaaagc      780

uaaugagcaa uaacguccaa aucguuagac aacaaaguua uuccaucaug ugcaucauca      840

aagaagaagu ccucgccuac gucguacaac ucccccucua uggcgucauc gacacccccu      900

gcuggaaacu gcacacauca ccccucugca ccacaaacac caaagaaggc ucaaacaucu      960

gccuaacucg caccgaccgc ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc     1020

cccaagccga aacaugcaaa guucaaucca accgcgucuu cugcgacaca augaacucca     1080

gaacgcuccc cagcgaaguc aaccucugua acguagacau cuucaacccu aaguacgacu     1140

gcaaaaucau gaccuccaaa acugauguau ccuccuccgu caucacaucc cugggcgcca     1200

ucgucagcug cuacggcaaa acaaaaugca cugccucaaa caaaugccga gguaucauaa     1260

agaccuucuc aaacggaugc gauuacguca gcaacaaagg cgucgacacc gucagugucg     1320

gcaacacccu cuacuacguc aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac     1380

ccaucaucaa cuucuacgac ccccucgucu uccccagcga cgaguucgac gccuccaucu     1440

cacaagucaa cgaaaagaua aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc     1500

ugcauaacgu caacgccggc aaauccacca caaacaucau gaucacuacc auaaucaucg     1560

ucauaaucgu aauccuccua ucucuuaucg cagucggccu acuacucuac ugcaaagccc     1620

gcuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  5856
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5856
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5857
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5857
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5858
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5858
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5859
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5859
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5860
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5860
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5861
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5861
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5862
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5862
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac ugaaagcaaa ugccaucaca accauacuaa cugccgucac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucca caugcucagc aguaucaaaa      300

ggauaucuau cggcacuuag aacuggaugg uacacaagug uuauaacuau agaacucuca      360

aacauaaaag aaaacaaaug caauggaaca gacgcaaaag uaaaacuaau aaaacaagaa      420

cucgauaaau auaaaaaugc aguaaccgaa cuacaacuau uaaugcaaag cacacccgca      480

acaggcagcg gaucagcaau agcaagcgga gucgcaguau guaaaguacu acaucuagaa      540

ggagaaguca acaaaaucaa aucugcacuu cuauccacaa acaaagcugu aguaucccua      600

uccggaugcg gagucucagu auuaacuuuu aaaguacuag accuuaaaaa cuacauagau      660

aaacaacuau uaccaauacu aaauaaacaa ucaugcagca uauccaauau agagacagua      720

auugaauuuc aacaaaaaaa caacagauua cuagaaauua cucgugaauu uuccguaaau      780

gccggaguca caacaccagu aucaaccuau augcuaacaa acagcgaacu acuuagcuua      840

auaaaugaca ugccaauaac aaaugaccaa aaaaaacuua ugucaaauaa cguacaaauc      900

gucagacaac aauccuacuc uauaaugugu auaauuaaag aagaaguccu agcauacgua      960

guucaauuac cacucuaugg aguaauagau acaccaugcu ggaaacuaca cacgucacca     1020

cuauguacaa caaacacaaa agaaggaucc aauauaugcc uaacaagaac cgacagaggc     1080

ugguauugug acaacgcagg auccguuuca uucuucccac aagcagaaac cuguaaagua     1140

caaucuaaua gaguauuuug cgacacaaug aacaguagaa cacuaccaag cgagguuaau     1200

cuauguaacg uagacauauu caauccaaaa uaugauugca aaauaaugac aucaaaaaca     1260

gauguaucgu cgaguguaau aacaagucug ggagcuauag uaagcugcua cggcaagacg     1320

aaauguaccg cuucaaauaa augcagagga aucauuaaaa cauucucgaa cggaugcgac     1380

uacguaagua auaaaggugu cgacaccgua ucaguaggga auacauuaua cuacgucaac     1440

aaacaagaag gaaaaucucu auauguaaaa ggagaaccaa uaauaaauuu cuaugacccu     1500

cuaguauucc caucagauga auuugacgcu uccauaucac aaguaaacga aaaaaucaau     1560

caaucuuuag cauucauacg aaaaagugau gaacuccuac acaacgucaa cgcaggaaaa     1620

agcacaacaa auauaaugau cacaacaauc aucauaguaa uaauaguaau acuacuauca     1680

uuaauagcag uaggauuauu gcuuuacugc aaagcacgau agggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5863
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5863
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acaauacuca ccgccguaac cuucugcuuu      240

gcgucgggac aaaacaucac cgaagaguuc uaccaaucca cuugcuccgc aguaagcaaa      300

ggauaccucu ccgcccugcg aaccgguugg uacacaucag ucaucacaau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcacc gacgcaaagg ucaaauuaau caagcaagaa      420

cuagacaaau acaaaaacgc cgucacagaa cuccagcugc uaaugcagag cacacccgca      480

acuggcagcg gauccgccau cgcaucagga gucgccgugu gcaaaguccu acaccucgaa      540

ggagaaguga acaaaaucaa aucagcccua cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gugucuccgu ccuaaccuuc aaagugcuag accucaagaa cuacaucgac      660

aaacaacucc uaccaauacu caacaagcaa ucuugcucca ucuccaacau cgaaaccgua      720

aucgaguucc aacagaagaa caaccgccuc cucgaaauca cccgcgaguu cucugucaac      780

gcagggguca ccacucccgu cuccacauac augcucacaa acuccgaacu ccucagccuc      840

aucaacgaca ugcccauaac caacgaccag aaaaagcuaa ugagcaauaa cguccaaauc      900

guuagacaac aaaguuauuc caucaugugc aucaucaaag aagaaguccu cgccuacguc      960

guacaacucc cccucuaugg cgucaucgac acccccugcu ggaaacugca cacaucaccc     1020

cucugcacca caaacaccaa agaaggcuca aacaucugcc uaacucgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cagcguauca uucuuucccc aagccgaaac augcaaaguu     1140

caauccaacc gcgucuucug cgacacaaug aacuccagaa cgcuccccag cgaagucaac     1200

cucuguaacg uagacaucuu caacccuaag uacgacugca aaaucaugac cuccaaaacu     1260

gauguauccu ccuccgucau cacaucccug ggcgccaucg ucagcugcua cggcaaaaca     1320

aaaugcacug ccucaaacaa augccgaggu aucauaaaga ccuucucaaa cggaugcgau     1380

uacgucagca acaaaggcgu cgacaccguc agugucggca acacccucua cuacgucaac     1440

aaacaagaag gaaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccagcgacga guucgacgcc uccaucucac aagucaacga aaagauaaac     1560

caaucucuag ccuucauccg caaauccgau gaacuccugc auaacgucaa cgccggcaaa     1620

uccaccacaa acaucaugau cacuaccaua aucaucguca uaaucguaau ccuccuaucu     1680

cuuaucgcag ucggccuacu acucuacugc aaagcccgcu aaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  5864
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5864
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      660

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      720

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      780

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      900

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      960

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1020

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1080

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1260

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1380

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1440

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1560

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1620

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5865
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5865
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      420

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      480

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      540

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      600

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      660

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      720

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc      960

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg     1020

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1140

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1200

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1260

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1380

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1440

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1500

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1560

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1620

agccugaucg ccguggggcu ccugcuguac ugcaaggccc ggugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5866
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5866
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      600

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      660

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      720

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      840

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      900

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      960

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1020

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1260

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1320

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1380

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1440

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1500

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1560

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1620

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5867
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5867
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      420

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      480

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      540

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      600

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      660

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      720

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      780

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      840

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau      900

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc      960

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu     1020

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1080

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1140

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1200

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1260

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1320

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1380

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1440

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1500

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1560

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1620

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5868
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5868
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      660

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      720

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      780

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      960

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1020

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1080

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1140

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1200

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1260

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1380

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1440

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1560

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1620

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5869
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5869
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      420

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      480

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      540

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      600

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      660

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      720

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      780

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      840

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau      900

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu      960

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc     1020

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1080

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1140

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1200

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1260

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1320

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1380

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1440

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1500

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1560

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1620

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gaugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5870
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5870
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuuuuaa uacugaaagc aaaugccauc acaaccauac uaacugccgu cacauucugc      180

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau ccacaugcuc agcaguauca      240

aaaggauauc uaucggcacu uagaacugga ugguacacaa guguuauaac uauagaacuc      300

ucaaacauaa aagaaaacaa augcaaugga acagacgcaa aaguaaaacu aauaaaacaa      360

gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac uauuaaugca aagcacaccc      420

gcaacaggca gcggaucagc aauagcaagc ggagucgcag uauguaaagu acuacaucua      480

gaaggagaag ucaacaaaau caaaucugca cuucuaucca caaacaaagc uguaguaucc      540

cuauccggau gcggagucuc aguauuaacu uuuaaaguac uagaccuuaa aaacuacaua      600

gauaaacaac uauuaccaau acuaaauaaa caaucaugca gcauauccaa uauagagaca      660

guaauugaau uucaacaaaa aaacaacaga uuacuagaaa uuacucguga auuuuccgua      720

aaugccggag ucacaacacc aguaucaacc uauaugcuaa caaacagcga acuacuuagc      780

uuaauaaaug acaugccaau aacaaaugac caaaaaaaac uuaugucaaa uaacguacaa      840

aucgucagac aacaauccua cucuauaaug uguauaauua aagaagaagu ccuagcauac      900

guaguucaau uaccacucua uggaguaaua gauacaccau gcuggaaacu acacacguca      960

ccacuaugua caacaaacac aaaagaagga uccaauauau gccuaacaag aaccgacaga     1020

ggcugguauu gugacaacgc aggauccguu ucauucuucc cacaagcaga aaccuguaaa     1080

guacaaucua auagaguauu uugcgacaca augaacagua gaacacuacc aagcgagguu     1140

aaucuaugua acguagacau auucaaucca aaauaugauu gcaaaauaau gacaucaaaa     1200

acagauguau cgucgagugu aauaacaagu cugggagcua uaguaagcug cuacggcaag     1260

acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua aaacauucuc gaacggaugc     1320

gacuacguaa guaauaaagg ugucgacacc guaucaguag ggaauacauu auacuacguc     1380

aacaaacaag aaggaaaauc ucuauaugua aaaggagaac caauaauaaa uuucuaugac     1440

ccucuaguau ucccaucaga ugaauuugac gcuuccauau cacaaguaaa cgaaaaaauc     1500

aaucaaucuu uagcauucau acgaaaaagu gaugaacucc uacacaacgu caacgcagga     1560

aaaagcacaa caaauauaau gaucacaaca aucaucauag uaauaauagu aauacuacua     1620

ucauuaauag caguaggauu auugcuuuac ugcaaagcac gauagggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5871
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5871
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccucaaagc caacgccaua accacaauac ucaccgccgu aaccuucugc      180

uuugcgucgg gacaaaacau caccgaagag uucuaccaau ccacuugcuc cgcaguaagc      240

aaaggauacc ucuccgcccu gcgaaccggu ugguacacau cagucaucac aaucgaacuc      300

ucaaacauaa aagaaaacaa augcaacggc accgacgcaa aggucaaauu aaucaagcaa      360

gaacuagaca aauacaaaaa cgccgucaca gaacuccagc ugcuaaugca gagcacaccc      420

gcaacuggca gcggauccgc caucgcauca ggagucgccg ugugcaaagu ccuacaccuc      480

gaaggagaag ugaacaaaau caaaucagcc cuacucucca ccaacaaggc cgucgucucc      540

cucuccggcu gcggugucuc cguccuaacc uucaaagugc uagaccucaa gaacuacauc      600

gacaaacaac uccuaccaau acucaacaag caaucuugcu ccaucuccaa caucgaaacc      660

guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa ucacccgcga guucucuguc      720

aacgcagggg ucaccacucc cgucuccaca uacaugcuca caaacuccga acuccucagc      780

cucaucaacg acaugcccau aaccaacgac cagaaaaagc uaaugagcaa uaacguccaa      840

aucguuagac aacaaaguua uuccaucaug ugcaucauca aagaagaagu ccucgccuac      900

gucguacaac ucccccucua uggcgucauc gacacccccu gcuggaaacu gcacacauca      960

ccccucugca ccacaaacac caaagaaggc ucaaacaucu gccuaacucg caccgaccgc     1020

ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc cccaagccga aacaugcaaa     1080

guucaaucca accgcgucuu cugcgacaca augaacucca gaacgcuccc cagcgaaguc     1140

aaccucugua acguagacau cuucaacccu aaguacgacu gcaaaaucau gaccuccaaa     1200

acugauguau ccuccuccgu caucacaucc cugggcgcca ucgucagcug cuacggcaaa     1260

acaaaaugca cugccucaaa caaaugccga gguaucauaa agaccuucuc aaacggaugc     1320

gauuacguca gcaacaaagg cgucgacacc gucagugucg gcaacacccu cuacuacguc     1380

aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac ccaucaucaa cuucuacgac     1440

ccccucgucu uccccagcga cgaguucgac gccuccaucu cacaagucaa cgaaaagaua     1500

aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc ugcauaacgu caacgccggc     1560

aaauccacca caaacaucau gaucacuacc auaaucaucg ucauaaucgu aauccuccua     1620

ucucuuaucg cagucggccu acuacucuac ugcaaagccc gcuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  5872
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5872
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5873
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5873
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccggugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5874
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5874
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5875
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5875
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5876
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5876
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5877
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5877
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagaugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5878
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5878
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacugaaa      120

gcaaaugcca ucacaaccau acuaacugcc gucacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca auccacaugc ucagcaguau caaaaggaua ucuaucggca      240

cuuagaacug gaugguacac aaguguuaua acuauagaac ucucaaacau aaaagaaaac      300

aaaugcaaug gaacagacgc aaaaguaaaa cuaauaaaac aagaacucga uaaauauaaa      360

aaugcaguaa ccgaacuaca acuauuaaug caaagcacac ccgcaacagg cagcggauca      420

gcaauagcaa gcggagucgc aguauguaaa guacuacauc uagaaggaga agucaacaaa      480

aucaaaucug cacuucuauc cacaaacaaa gcuguaguau cccuauccgg augcggaguc      540

ucaguauuaa cuuuuaaagu acuagaccuu aaaaacuaca uagauaaaca acuauuacca      600

auacuaaaua aacaaucaug cagcauaucc aauauagaga caguaauuga auuucaacaa      660

aaaaacaaca gauuacuaga aauuacucgu gaauuuuccg uaaaugccgg agucacaaca      720

ccaguaucaa ccuauaugcu aacaaacagc gaacuacuua gcuuaauaaa ugacaugcca      780

auaacaaaug accaaaaaaa acuuauguca aauaacguac aaaucgucag acaacaaucc      840

uacucuauaa uguguauaau uaaagaagaa guccuagcau acguaguuca auuaccacuc      900

uauggaguaa uagauacacc augcuggaaa cuacacacgu caccacuaug uacaacaaac      960

acaaaagaag gauccaauau augccuaaca agaaccgaca gaggcuggua uugugacaac     1020

gcaggauccg uuucauucuu cccacaagca gaaaccugua aaguacaauc uaauagagua     1080

uuuugcgaca caaugaacag uagaacacua ccaagcgagg uuaaucuaug uaacguagac     1140

auauucaauc caaaauauga uugcaaaaua augacaucaa aaacagaugu aucgucgagu     1200

guaauaacaa gucugggagc uauaguaagc ugcuacggca agacgaaaug uaccgcuuca     1260

aauaaaugca gaggaaucau uaaaacauuc ucgaacggau gcgacuacgu aaguaauaaa     1320

ggugucgaca ccguaucagu agggaauaca uuauacuacg ucaacaaaca agaaggaaaa     1380

ucucuauaug uaaaaggaga accaauaaua aauuucuaug acccucuagu auucccauca     1440

gaugaauuug acgcuuccau aucacaagua aacgaaaaaa ucaaucaauc uuuagcauuc     1500

auacgaaaaa gugaugaacu ccuacacaac gucaacgcag gaaaaagcac aacaaauaua     1560

augaucacaa caaucaucau aguaauaaua guaauacuac uaucauuaau agcaguagga     1620

uuauugcuuu acugcaaagc acgauaggga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5879
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5879
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacaau acucaccgcc guaaccuucu gcuuugcguc gggacaaaac      180

aucaccgaag aguucuacca auccacuugc uccgcaguaa gcaaaggaua ccucuccgcc      240

cugcgaaccg guugguacac aucagucauc acaaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaggucaaa uuaaucaagc aagaacuaga caaauacaaa      360

aacgccguca cagaacucca gcugcuaaug cagagcacac ccgcaacugg cagcggaucc      420

gccaucgcau caggagucgc cgugugcaaa guccuacacc ucgaaggaga agugaacaaa      480

aucaaaucag cccuacucuc caccaacaag gccgucgucu cccucuccgg cugcgguguc      540

uccguccuaa ccuucaaagu gcuagaccuc aagaacuaca ucgacaaaca acuccuacca      600

auacucaaca agcaaucuug cuccaucucc aacaucgaaa ccguaaucga guuccaacag      660

aagaacaacc gccuccucga aaucacccgc gaguucucug ucaacgcagg ggucaccacu      720

cccgucucca cauacaugcu cacaaacucc gaacuccuca gccucaucaa cgacaugccc      780

auaaccaacg accagaaaaa gcuaaugagc aauaacgucc aaaucguuag acaacaaagu      840

uauuccauca ugugcaucau caaagaagaa guccucgccu acgucguaca acucccccuc      900

uauggcguca ucgacacccc cugcuggaaa cugcacacau caccccucug caccacaaac      960

accaaagaag gcucaaacau cugccuaacu cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcagcg uaucauucuu uccccaagcc gaaacaugca aaguucaauc caaccgcguc     1080

uucugcgaca caaugaacuc cagaacgcuc cccagcgaag ucaaccucug uaacguagac     1140

aucuucaacc cuaaguacga cugcaaaauc augaccucca aaacugaugu auccuccucc     1200

gucaucacau cccugggcgc caucgucagc ugcuacggca aaacaaaaug cacugccuca     1260

aacaaaugcc gagguaucau aaagaccuuc ucaaacggau gcgauuacgu cagcaacaaa     1320

ggcgucgaca ccgucagugu cggcaacacc cucuacuacg ucaacaaaca agaaggaaaa     1380

ucccucuacg ucaaaggcga acccaucauc aacuucuacg acccccucgu cuuccccagc     1440

gacgaguucg acgccuccau cucacaaguc aacgaaaaga uaaaccaauc ucuagccuuc     1500

auccgcaaau ccgaugaacu ccugcauaac gucaacgccg gcaaauccac cacaaacauc     1560

augaucacua ccauaaucau cgucauaauc guaauccucc uaucucuuau cgcagucggc     1620

cuacuacucu acugcaaagc ccgcuaagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  5880
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5880
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5881
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5881
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccggugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5882
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5882
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5883
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5883
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5884
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5884
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5885
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5885
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagaugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5886
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5886
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacugaaa gcaaaugcca ucacaaccau acuaacugcc      120

gucacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca auccacaugc      180

ucagcaguau caaaaggaua ucuaucggca cuuagaacug gaugguacac aaguguuaua      240

acuauagaac ucucaaacau aaaagaaaac aaaugcaaug gaacagacgc aaaaguaaaa      300

cuaauaaaac aagaacucga uaaauauaaa aaugcaguaa ccgaacuaca acuauuaaug      360

caaagcacac ccgcaacagg cagcggauca gcaauagcaa gcggagucgc aguauguaaa      420

guacuacauc uagaaggaga agucaacaaa aucaaaucug cacuucuauc cacaaacaaa      480

gcuguaguau cccuauccgg augcggaguc ucaguauuaa cuuuuaaagu acuagaccuu      540

aaaaacuaca uagauaaaca acuauuacca auacuaaaua aacaaucaug cagcauaucc      600

aauauagaga caguaauuga auuucaacaa aaaaacaaca gauuacuaga aauuacucgu      660

gaauuuuccg uaaaugccgg agucacaaca ccaguaucaa ccuauaugcu aacaaacagc      720

gaacuacuua gcuuaauaaa ugacaugcca auaacaaaug accaaaaaaa acuuauguca      780

aauaacguac aaaucgucag acaacaaucc uacucuauaa uguguauaau uaaagaagaa      840

guccuagcau acguaguuca auuaccacuc uauggaguaa uagauacacc augcuggaaa      900

cuacacacgu caccacuaug uacaacaaac acaaaagaag gauccaauau augccuaaca      960

agaaccgaca gaggcuggua uugugacaac gcaggauccg uuucauucuu cccacaagca     1020

gaaaccugua aaguacaauc uaauagagua uuuugcgaca caaugaacag uagaacacua     1080

ccaagcgagg uuaaucuaug uaacguagac auauucaauc caaaauauga uugcaaaaua     1140

augacaucaa aaacagaugu aucgucgagu guaauaacaa gucugggagc uauaguaagc     1200

ugcuacggca agacgaaaug uaccgcuuca aauaaaugca gaggaaucau uaaaacauuc     1260

ucgaacggau gcgacuacgu aaguaauaaa ggugucgaca ccguaucagu agggaauaca     1320

uuauacuacg ucaacaaaca agaaggaaaa ucucuauaug uaaaaggaga accaauaaua     1380

aauuucuaug acccucuagu auucccauca gaugaauuug acgcuuccau aucacaagua     1440

aacgaaaaaa ucaaucaauc uuuagcauuc auacgaaaaa gugaugaacu ccuacacaac     1500

gucaacgcag gaaaaagcac aacaaauaua augaucacaa caaucaucau aguaauaaua     1560

guaauacuac uaucauuaau agcaguagga uuauugcuuu acugcaaagc acgauaggga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5887
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5887
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacaau acucaccgcc      120

guaaccuucu gcuuugcguc gggacaaaac aucaccgaag aguucuacca auccacuugc      180

uccgcaguaa gcaaaggaua ccucuccgcc cugcgaaccg guugguacac aucagucauc      240

acaaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcaccgacgc aaaggucaaa      300

uuaaucaagc aagaacuaga caaauacaaa aacgccguca cagaacucca gcugcuaaug      360

cagagcacac ccgcaacugg cagcggaucc gccaucgcau caggagucgc cgugugcaaa      420

guccuacacc ucgaaggaga agugaacaaa aucaaaucag cccuacucuc caccaacaag      480

gccgucgucu cccucuccgg cugcgguguc uccguccuaa ccuucaaagu gcuagaccuc      540

aagaacuaca ucgacaaaca acuccuacca auacucaaca agcaaucuug cuccaucucc      600

aacaucgaaa ccguaaucga guuccaacag aagaacaacc gccuccucga aaucacccgc      660

gaguucucug ucaacgcagg ggucaccacu cccgucucca cauacaugcu cacaaacucc      720

gaacuccuca gccucaucaa cgacaugccc auaaccaacg accagaaaaa gcuaaugagc      780

aauaacgucc aaaucguuag acaacaaagu uauuccauca ugugcaucau caaagaagaa      840

guccucgccu acgucguaca acucccccuc uauggcguca ucgacacccc cugcuggaaa      900

cugcacacau caccccucug caccacaaac accaaagaag gcucaaacau cugccuaacu      960

cgcaccgacc gcggcuggua cugcgacaac gccggcagcg uaucauucuu uccccaagcc     1020

gaaacaugca aaguucaauc caaccgcguc uucugcgaca caaugaacuc cagaacgcuc     1080

cccagcgaag ucaaccucug uaacguagac aucuucaacc cuaaguacga cugcaaaauc     1140

augaccucca aaacugaugu auccuccucc gucaucacau cccugggcgc caucgucagc     1200

ugcuacggca aaacaaaaug cacugccuca aacaaaugcc gagguaucau aaagaccuuc     1260

ucaaacggau gcgauuacgu cagcaacaaa ggcgucgaca ccgucagugu cggcaacacc     1320

cucuacuacg ucaacaaaca agaaggaaaa ucccucuacg ucaaaggcga acccaucauc     1380

aacuucuacg acccccucgu cuuccccagc gacgaguucg acgccuccau cucacaaguc     1440

aacgaaaaga uaaaccaauc ucuagccuuc auccgcaaau ccgaugaacu ccugcauaac     1500

gucaacgccg gcaaauccac cacaaacauc augaucacua ccauaaucau cgucauaauc     1560

guaauccucc uaucucuuau cgcagucggc cuacuacucu acugcaaagc ccgcuaagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  5888
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5888
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5889
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5889
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccggug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5890
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5890
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5891
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5891
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5892
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5892
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5893
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5893
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagaug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5894
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5894
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu gaaagcaaau gccaucacaa ccauacuaac ugccgucaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaauccac augcucagca      240

guaucaaaag gauaucuauc ggcacuuaga acuggauggu acacaagugu uauaacuaua      300

gaacucucaa acauaaaaga aaacaaaugc aauggaacag acgcaaaagu aaaacuaaua      360

aaacaagaac ucgauaaaua uaaaaaugca guaaccgaac uacaacuauu aaugcaaagc      420

acacccgcaa caggcagcgg aucagcaaua gcaagcggag ucgcaguaug uaaaguacua      480

caucuagaag gagaagucaa caaaaucaaa ucugcacuuc uauccacaaa caaagcugua      540

guaucccuau ccggaugcgg agucucagua uuaacuuuua aaguacuaga ccuuaaaaac      600

uacauagaua aacaacuauu accaauacua aauaaacaau caugcagcau auccaauaua      660

gagacaguaa uugaauuuca acaaaaaaac aacagauuac uagaaauuac ucgugaauuu      720

uccguaaaug ccggagucac aacaccagua ucaaccuaua ugcuaacaaa cagcgaacua      780

cuuagcuuaa uaaaugacau gccaauaaca aaugaccaaa aaaaacuuau gucaaauaac      840

guacaaaucg ucagacaaca auccuacucu auaaugugua uaauuaaaga agaaguccua      900

gcauacguag uucaauuacc acucuaugga guaauagaua caccaugcug gaaacuacac      960

acgucaccac uauguacaac aaacacaaaa gaaggaucca auauaugccu aacaagaacc     1020

gacagaggcu gguauuguga caacgcagga uccguuucau ucuucccaca agcagaaacc     1080

uguaaaguac aaucuaauag aguauuuugc gacacaauga acaguagaac acuaccaagc     1140

gagguuaauc uauguaacgu agacauauuc aauccaaaau augauugcaa aauaaugaca     1200

ucaaaaacag auguaucguc gaguguaaua acaagucugg gagcuauagu aagcugcuac     1260

ggcaagacga aauguaccgc uucaaauaaa ugcagaggaa ucauuaaaac auucucgaac     1320

ggaugcgacu acguaaguaa uaaagguguc gacaccguau caguagggaa uacauuauac     1380

uacgucaaca aacaagaagg aaaaucucua uauguaaaag gagaaccaau aauaaauuuc     1440

uaugacccuc uaguauuccc aucagaugaa uuugacgcuu ccauaucaca aguaaacgaa     1500

aaaaucaauc aaucuuuagc auucauacga aaaagugaug aacuccuaca caacgucaac     1560

gcaggaaaaa gcacaacaaa uauaaugauc acaacaauca ucauaguaau aauaguaaua     1620

cuacuaucau uaauagcagu aggauuauug cuuuacugca aagcacgaua gggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5895
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5895
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca caauacucac cgccguaacc      180

uucugcuuug cgucgggaca aaacaucacc gaagaguucu accaauccac uugcuccgca      240

guaagcaaag gauaccucuc cgcccugcga accgguuggu acacaucagu caucacaauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcaccg acgcaaaggu caaauuaauc      360

aagcaagaac uagacaaaua caaaaacgcc gucacagaac uccagcugcu aaugcagagc      420

acacccgcaa cuggcagcgg auccgccauc gcaucaggag ucgccgugug caaaguccua      480

caccucgaag gagaagugaa caaaaucaaa ucagcccuac ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg ugucuccguc cuaaccuuca aagugcuaga ccucaagaac      600

uacaucgaca aacaacuccu accaauacuc aacaagcaau cuugcuccau cuccaacauc      660

gaaaccguaa ucgaguucca acagaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

ucugucaacg caggggucac cacucccguc uccacauaca ugcucacaaa cuccgaacuc      780

cucagccuca ucaacgacau gcccauaacc aacgaccaga aaaagcuaau gagcaauaac      840

guccaaaucg uuagacaaca aaguuauucc aucaugugca ucaucaaaga agaaguccuc      900

gccuacgucg uacaacuccc ccucuauggc gucaucgaca cccccugcug gaaacugcac      960

acaucacccc ucugcaccac aaacaccaaa gaaggcucaa acaucugccu aacucgcacc     1020

gaccgcggcu gguacugcga caacgccggc agcguaucau ucuuucccca agccgaaaca     1080

ugcaaaguuc aauccaaccg cgucuucugc gacacaauga acuccagaac gcuccccagc     1140

gaagucaacc ucuguaacgu agacaucuuc aacccuaagu acgacugcaa aaucaugacc     1200

uccaaaacug auguauccuc cuccgucauc acaucccugg gcgccaucgu cagcugcuac     1260

ggcaaaacaa aaugcacugc cucaaacaaa ugccgaggua ucauaaagac cuucucaaac     1320

ggaugcgauu acgucagcaa caaaggcguc gacaccguca gugucggcaa cacccucuac     1380

uacgucaaca aacaagaagg aaaaucccuc uacgucaaag gcgaacccau caucaacuuc     1440

uacgaccccc ucgucuuccc cagcgacgag uucgacgccu ccaucucaca agucaacgaa     1500

aagauaaacc aaucucuagc cuucauccgc aaauccgaug aacuccugca uaacgucaac     1560

gccggcaaau ccaccacaaa caucaugauc acuaccauaa ucaucgucau aaucguaauc     1620

cuccuaucuc uuaucgcagu cggccuacua cucuacugca aagcccgcua aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  5896
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5896
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5897
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5897
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5898
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5898
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5899
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5899
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5900
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5900
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5901
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5901
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagaugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5902
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5902
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacugaa agcaaaugcc      120

aucacaacca uacuaacugc cgucacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aauccacaug cucagcagua ucaaaaggau aucuaucggc acuuagaacu      240

ggaugguaca caaguguuau aacuauagaa cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacagacg caaaaguaaa acuaauaaaa caagaacucg auaaauauaa aaaugcagua      360

accgaacuac aacuauuaau gcaaagcaca cccgcaacag gcagcggauc agcaauagca      420

agcggagucg caguauguaa aguacuacau cuagaaggag aagucaacaa aaucaaaucu      480

gcacuucuau ccacaaacaa agcuguagua ucccuauccg gaugcggagu cucaguauua      540

acuuuuaaag uacuagaccu uaaaaacuac auagauaaac aacuauuacc aauacuaaau      600

aaacaaucau gcagcauauc caauauagag acaguaauug aauuucaaca aaaaaacaac      660

agauuacuag aaauuacucg ugaauuuucc guaaaugccg gagucacaac accaguauca      720

accuauaugc uaacaaacag cgaacuacuu agcuuaauaa augacaugcc aauaacaaau      780

gaccaaaaaa aacuuauguc aaauaacgua caaaucguca gacaacaauc cuacucuaua      840

auguguauaa uuaaagaaga aguccuagca uacguaguuc aauuaccacu cuauggagua      900

auagauacac caugcuggaa acuacacacg ucaccacuau guacaacaaa cacaaaagaa      960

ggauccaaua uaugccuaac aagaaccgac agaggcuggu auugugacaa cgcaggaucc     1020

guuucauucu ucccacaagc agaaaccugu aaaguacaau cuaauagagu auuuugcgac     1080

acaaugaaca guagaacacu accaagcgag guuaaucuau guaacguaga cauauucaau     1140

ccaaaauaug auugcaaaau aaugacauca aaaacagaug uaucgucgag uguaauaaca     1200

agucugggag cuauaguaag cugcuacggc aagacgaaau guaccgcuuc aaauaaaugc     1260

agaggaauca uuaaaacauu cucgaacgga ugcgacuacg uaaguaauaa aggugucgac     1320

accguaucag uagggaauac auuauacuac gucaacaaac aagaaggaaa aucucuauau     1380

guaaaaggag aaccaauaau aaauuucuau gacccucuag uauucccauc agaugaauuu     1440

gacgcuucca uaucacaagu aaacgaaaaa aucaaucaau cuuuagcauu cauacgaaaa     1500

agugaugaac uccuacacaa cgucaacgca ggaaaaagca caacaaauau aaugaucaca     1560

acaaucauca uaguaauaau aguaauacua cuaucauuaa uagcaguagg auuauugcuu     1620

uacugcaaag cacgauaggg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5903
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5903
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacaa uacucaccgc cguaaccuuc ugcuuugcgu cgggacaaaa caucaccgaa      180

gaguucuacc aauccacuug cuccgcagua agcaaaggau accucuccgc ccugcgaacc      240

gguugguaca caucagucau cacaaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaggucaa auuaaucaag caagaacuag acaaauacaa aaacgccguc      360

acagaacucc agcugcuaau gcagagcaca cccgcaacug gcagcggauc cgccaucgca      420

ucaggagucg ccgugugcaa aguccuacac cucgaaggag aagugaacaa aaucaaauca      480

gcccuacucu ccaccaacaa ggccgucguc ucccucuccg gcugcggugu cuccguccua      540

accuucaaag ugcuagaccu caagaacuac aucgacaaac aacuccuacc aauacucaac      600

aagcaaucuu gcuccaucuc caacaucgaa accguaaucg aguuccaaca gaagaacaac      660

cgccuccucg aaaucacccg cgaguucucu gucaacgcag gggucaccac ucccgucucc      720

acauacaugc ucacaaacuc cgaacuccuc agccucauca acgacaugcc cauaaccaac      780

gaccagaaaa agcuaaugag caauaacguc caaaucguua gacaacaaag uuauuccauc      840

augugcauca ucaaagaaga aguccucgcc uacgucguac aacucccccu cuauggcguc      900

aucgacaccc ccugcuggaa acugcacaca ucaccccucu gcaccacaaa caccaaagaa      960

ggcucaaaca ucugccuaac ucgcaccgac cgcggcuggu acugcgacaa cgccggcagc     1020

guaucauucu uuccccaagc cgaaacaugc aaaguucaau ccaaccgcgu cuucugcgac     1080

acaaugaacu ccagaacgcu ccccagcgaa gucaaccucu guaacguaga caucuucaac     1140

ccuaaguacg acugcaaaau caugaccucc aaaacugaug uauccuccuc cgucaucaca     1200

ucccugggcg ccaucgucag cugcuacggc aaaacaaaau gcacugccuc aaacaaaugc     1260

cgagguauca uaaagaccuu cucaaacgga ugcgauuacg ucagcaacaa aggcgucgac     1320

accgucagug ucggcaacac ccucuacuac gucaacaaac aagaaggaaa aucccucuac     1380

gucaaaggcg aacccaucau caacuucuac gacccccucg ucuuccccag cgacgaguuc     1440

gacgccucca ucucacaagu caacgaaaag auaaaccaau cucuagccuu cauccgcaaa     1500

uccgaugaac uccugcauaa cgucaacgcc ggcaaaucca ccacaaacau caugaucacu     1560

accauaauca ucgucauaau cguaauccuc cuaucucuua ucgcagucgg ccuacuacuc     1620

uacugcaaag cccgcuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  5904
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5904
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5905
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5905
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5906
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5906
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5907
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5907
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5908
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5908
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5909
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5909
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagaugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5910
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5910
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacugaa agcaaaugcc      120

aucacaacca uacuaacugc cgucacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aauccacaug cucagcagua ucaaaaggau aucuaucggc acuuagaacu      240

ggaugguaca caaguguuau aacuauagaa cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacagacg caaaaguaaa acuaauaaaa caagaacucg auaaauauaa aaaugcagua      360

accgaacuac aacuauuaau gcaaagcaca cccgcaacag gcagcggauc agcaauagca      420

agcggagucg caguauguaa aguacuacau cuagaaggag aagucaacaa aaucaaaucu      480

gcacuucuau ccacaaacaa agcuguagua ucccuauccg gaugcggagu cucaguauua      540

acuuuuaaag uacuagaccu uaaaaacuac auagauaaac aacuauuacc aauacuaaau      600

aaacaaucau gcagcauauc caauauagag acaguaauug aauuucaaca aaaaaacaac      660

agauuacuag aaauuacucg ugaauuuucc guaaaugccg gagucacaac accaguauca      720

accuauaugc uaacaaacag cgaacuacuu agcuuaauaa augacaugcc aauaacaaau      780

gaccaaaaaa aacuuauguc aaauaacgua caaaucguca gacaacaauc cuacucuaua      840

auguguauaa uuaaagaaga aguccuagca uacguaguuc aauuaccacu cuauggagua      900

auagauacac caugcuggaa acuacacacg ucaccacuau guacaacaaa cacaaaagaa      960

ggauccaaua uaugccuaac aagaaccgac agaggcuggu auugugacaa cgcaggaucc     1020

guuucauucu ucccacaagc agaaaccugu aaaguacaau cuaauagagu auuuugcgac     1080

acaaugaaca guagaacacu accaagcgag guuaaucuau guaacguaga cauauucaau     1140

ccaaaauaug auugcaaaau aaugacauca aaaacagaug uaucgucgag uguaauaaca     1200

agucugggag cuauaguaag cugcuacggc aagacgaaau guaccgcuuc aaauaaaugc     1260

agaggaauca uuaaaacauu cucgaacgga ugcgacuacg uaaguaauaa aggugucgac     1320

accguaucag uagggaauac auuauacuac gucaacaaac aagaaggaaa aucucuauau     1380

guaaaaggag aaccaauaau aaauuucuau gacccucuag uauucccauc agaugaauuu     1440

gacgcuucca uaucacaagu aaacgaaaaa aucaaucaau cuuuagcauu cauacgaaaa     1500

agugaugaac uccuacacaa cgucaacgca ggaaaaagca caacaaauau aaugaucaca     1560

acaaucauca uaguaauaau aguaauacua cuaucauuaa uagcaguagg auuauugcuu     1620

uacugcaaag cacgauaggg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5911
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5911
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacaa uacucaccgc cguaaccuuc ugcuuugcgu cgggacaaaa caucaccgaa      180

gaguucuacc aauccacuug cuccgcagua agcaaaggau accucuccgc ccugcgaacc      240

gguugguaca caucagucau cacaaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaggucaa auuaaucaag caagaacuag acaaauacaa aaacgccguc      360

acagaacucc agcugcuaau gcagagcaca cccgcaacug gcagcggauc cgccaucgca      420

ucaggagucg ccgugugcaa aguccuacac cucgaaggag aagugaacaa aaucaaauca      480

gcccuacucu ccaccaacaa ggccgucguc ucccucuccg gcugcggugu cuccguccua      540

accuucaaag ugcuagaccu caagaacuac aucgacaaac aacuccuacc aauacucaac      600

aagcaaucuu gcuccaucuc caacaucgaa accguaaucg aguuccaaca gaagaacaac      660

cgccuccucg aaaucacccg cgaguucucu gucaacgcag gggucaccac ucccgucucc      720

acauacaugc ucacaaacuc cgaacuccuc agccucauca acgacaugcc cauaaccaac      780

gaccagaaaa agcuaaugag caauaacguc caaaucguua gacaacaaag uuauuccauc      840

augugcauca ucaaagaaga aguccucgcc uacgucguac aacucccccu cuauggcguc      900

aucgacaccc ccugcuggaa acugcacaca ucaccccucu gcaccacaaa caccaaagaa      960

ggcucaaaca ucugccuaac ucgcaccgac cgcggcuggu acugcgacaa cgccggcagc     1020

guaucauucu uuccccaagc cgaaacaugc aaaguucaau ccaaccgcgu cuucugcgac     1080

acaaugaacu ccagaacgcu ccccagcgaa gucaaccucu guaacguaga caucuucaac     1140

ccuaaguacg acugcaaaau caugaccucc aaaacugaug uauccuccuc cgucaucaca     1200

ucccugggcg ccaucgucag cugcuacggc aaaacaaaau gcacugccuc aaacaaaugc     1260

cgagguauca uaaagaccuu cucaaacgga ugcgauuacg ucagcaacaa aggcgucgac     1320

accgucagug ucggcaacac ccucuacuac gucaacaaac aagaaggaaa aucccucuac     1380

gucaaaggcg aacccaucau caacuucuac gacccccucg ucuuccccag cgacgaguuc     1440

gacgccucca ucucacaagu caacgaaaag auaaaccaau cucuagccuu cauccgcaaa     1500

uccgaugaac uccugcauaa cgucaacgcc ggcaaaucca ccacaaacau caugaucacu     1560

accauaauca ucgucauaau cguaauccuc cuaucucuua ucgcagucgg ccuacuacuc     1620

uacugcaaag cccgcuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  5912
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5912
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5913
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5913
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5914
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5914
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5915
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5915
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5916
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5916
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5917
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5917
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagaugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5918
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5918
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacugaa agcaaaugcc      120

aucacaacca uacuaacugc cgucacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aauccacaug cucagcagua ucaaaaggau aucuaucggc acuuagaacu      240

ggaugguaca caaguguuau aacuauagaa cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacagacg caaaaguaaa acuaauaaaa caagaacucg auaaauauaa aaaugcagua      360

accgaacuac aacuauuaau gcaaagcaca cccgcaacag gcagcggauc agcaauagca      420

agcggagucg caguauguaa aguacuacau cuagaaggag aagucaacaa aaucaaaucu      480

gcacuucuau ccacaaacaa agcuguagua ucccuauccg gaugcggagu cucaguauua      540

acuuuuaaag uacuagaccu uaaaaacuac auagauaaac aacuauuacc aauacuaaau      600

aaacaaucau gcagcauauc caauauagag acaguaauug aauuucaaca aaaaaacaac      660

agauuacuag aaauuacucg ugaauuuucc guaaaugccg gagucacaac accaguauca      720

accuauaugc uaacaaacag cgaacuacuu agcuuaauaa augacaugcc aauaacaaau      780

gaccaaaaaa aacuuauguc aaauaacgua caaaucguca gacaacaauc cuacucuaua      840

auguguauaa uuaaagaaga aguccuagca uacguaguuc aauuaccacu cuauggagua      900

auagauacac caugcuggaa acuacacacg ucaccacuau guacaacaaa cacaaaagaa      960

ggauccaaua uaugccuaac aagaaccgac agaggcuggu auugugacaa cgcaggaucc     1020

guuucauucu ucccacaagc agaaaccugu aaaguacaau cuaauagagu auuuugcgac     1080

acaaugaaca guagaacacu accaagcgag guuaaucuau guaacguaga cauauucaau     1140

ccaaaauaug auugcaaaau aaugacauca aaaacagaug uaucgucgag uguaauaaca     1200

agucugggag cuauaguaag cugcuacggc aagacgaaau guaccgcuuc aaauaaaugc     1260

agaggaauca uuaaaacauu cucgaacgga ugcgacuacg uaaguaauaa aggugucgac     1320

accguaucag uagggaauac auuauacuac gucaacaaac aagaaggaaa aucucuauau     1380

guaaaaggag aaccaauaau aaauuucuau gacccucuag uauucccauc agaugaauuu     1440

gacgcuucca uaucacaagu aaacgaaaaa aucaaucaau cuuuagcauu cauacgaaaa     1500

agugaugaac uccuacacaa cgucaacgca ggaaaaagca caacaaauau aaugaucaca     1560

acaaucauca uaguaauaau aguaauacua cuaucauuaa uagcaguagg auuauugcuu     1620

uacugcaaag cacgauaggg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5919
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5919
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacaa uacucaccgc cguaaccuuc ugcuuugcgu cgggacaaaa caucaccgaa      180

gaguucuacc aauccacuug cuccgcagua agcaaaggau accucuccgc ccugcgaacc      240

gguugguaca caucagucau cacaaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaggucaa auuaaucaag caagaacuag acaaauacaa aaacgccguc      360

acagaacucc agcugcuaau gcagagcaca cccgcaacug gcagcggauc cgccaucgca      420

ucaggagucg ccgugugcaa aguccuacac cucgaaggag aagugaacaa aaucaaauca      480

gcccuacucu ccaccaacaa ggccgucguc ucccucuccg gcugcggugu cuccguccua      540

accuucaaag ugcuagaccu caagaacuac aucgacaaac aacuccuacc aauacucaac      600

aagcaaucuu gcuccaucuc caacaucgaa accguaaucg aguuccaaca gaagaacaac      660

cgccuccucg aaaucacccg cgaguucucu gucaacgcag gggucaccac ucccgucucc      720

acauacaugc ucacaaacuc cgaacuccuc agccucauca acgacaugcc cauaaccaac      780

gaccagaaaa agcuaaugag caauaacguc caaaucguua gacaacaaag uuauuccauc      840

augugcauca ucaaagaaga aguccucgcc uacgucguac aacucccccu cuauggcguc      900

aucgacaccc ccugcuggaa acugcacaca ucaccccucu gcaccacaaa caccaaagaa      960

ggcucaaaca ucugccuaac ucgcaccgac cgcggcuggu acugcgacaa cgccggcagc     1020

guaucauucu uuccccaagc cgaaacaugc aaaguucaau ccaaccgcgu cuucugcgac     1080

acaaugaacu ccagaacgcu ccccagcgaa gucaaccucu guaacguaga caucuucaac     1140

ccuaaguacg acugcaaaau caugaccucc aaaacugaug uauccuccuc cgucaucaca     1200

ucccugggcg ccaucgucag cugcuacggc aaaacaaaau gcacugccuc aaacaaaugc     1260

cgagguauca uaaagaccuu cucaaacgga ugcgauuacg ucagcaacaa aggcgucgac     1320

accgucagug ucggcaacac ccucuacuac gucaacaaac aagaaggaaa aucccucuac     1380

gucaaaggcg aacccaucau caacuucuac gacccccucg ucuuccccag cgacgaguuc     1440

gacgccucca ucucacaagu caacgaaaag auaaaccaau cucuagccuu cauccgcaaa     1500

uccgaugaac uccugcauaa cgucaacgcc ggcaaaucca ccacaaacau caugaucacu     1560

accauaauca ucgucauaau cguaauccuc cuaucucuua ucgcagucgg ccuacuacuc     1620

uacugcaaag cccgcuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  5920
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5920
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccaucag caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccggacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcaa gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5921
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5921
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agcuccugau gcaguccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cucgagggcg aggugaacaa gaucaagucc      480

gcccugcuga gcaccaacaa ggccgugguc ucccucagcg ggugcggcgu guccgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcagagcu gcuccaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gggucaccac gcccgugagc      720

accuacaugc ucaccaacag cgagcugcug ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccccu guacggcgug      900

aucgacacgc cgugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggguccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcgggcucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccggacccu ccccuccgag gucaaccugu gcaacgugga caucuucaac     1140

ccgaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccuggggg ccaucguguc cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcgucgac     1320

acggugagcg uggggaacac ccucuacuac gucaacaagc aggagggcaa gucccuguac     1380

gugaaggggg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg gcuccugcug     1620

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5922
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5922
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccaucuc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccgcacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcaa gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5923
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5923
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agcuucugau gcagucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucuguaa gguguugcac cucgagggcg aaguuaacaa aaucaagagu      480

gcucugcugu ccacgaauaa agccgugguc ucucucagcg guugcggggu guccguauua      540

acuuuuaagg uucuggaccu uaagaacuac auugauaaac aauugcugcc uauccuaaau      600

aagcagucau guaguauuag caacaucgag accgugauag aguuccagca gaaaaauaac      660

aggcuccugg aaauuacacg ggaguuuucu gucaaugcgg gagugacuac cccagugucc      720

acauauaugc uuaccaacuc agaacuguug agccucauca augacaugcc gauuacgaac      780

gaucaaaaga aacugaugag uaacaauguc cagaucguuc gccagcaguc uuacuccauc      840

augugcauua uaaaggagga aguguuagca uauguagugc aacugccccu cuacggcguc      900

aucgacacuc cuuguuggaa acuucauaca agcccacugu gcaccacuaa cacaaaggag      960

ggcucgaaua uuuguuugac ccgaacggau cguggguggu acugcgacaa cgccggaucu     1020

guguccuucu uuccccaggc ugaaaccugu aagguucagu caaauagagu guucugcgau     1080

acaaugaaca guagaacucu gccuagcgag gucaaucucu gcaacgugga caucuuuaau     1140

ccaaaauaug auuguaagau aaugaccucc aaaacagacg uaucuagcuc aguuauuacc     1200

agucugggug ccaucguguc cugcuacggc aagacuaaau guacagcaag caacaagugc     1260

agggggauca uuaagaccuu cucuaaugga ugugauuaug ucucaaacaa aggcguggac     1320

acugucagug uggguaauac gcuuuacuau guuaacaagc aagaggggaa aagccuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccuuugg uauucccauc cgaugaguuu     1440

gacgcuucua uaucgcaggu caacgagaaa aucaaccaga gccucgccuu cauucggaag     1500

uccgaugaac uguuacacaa ugugaacgcg ggcaagucaa caaccaauau caugaucacu     1560

accauuauaa ucguuauuau cgugauucug cuaagucuca ucgccgucgg ccugcuuuug     1620

uacugcaaag cacgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5924
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5924
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcaucag caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gcagaacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcaa gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5925
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5925
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agcugcugau gcaguccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cgguguguaa gguucuccac cuggaggggg aagugaacaa aaucaagagc      480

gcccuucugu cuaccaauaa agcugucgug ucccucagcg gaugcggcgu uucugugcug      540

acauuuaagg uccuugaccu gaagaacuac auugauaaac aacuccugcc uauccugaau      600

aagcaguccu guagcauuuc uaacaucgag accgugauug aguuccagca gaaaaauaac      660

cggcuccugg aaaucacgcg cgaguuuucc gugaaugccg gcgucacaac cccgguuagc      720

acauauaugc uuaccaacuc cgaacugcuc ucucugauca augacaugcc cauuaccaac      780

gaucaaaaga aacuuaugag caacaaugug cagaucguga gacagcaguc cuacagcauu      840

augugcauca uuaaggagga aguccuggcu uaugugguuc aacucccucu guacggggug      900

aucgacacac ccuguuggaa acugcauacg ucuccucucu gcaccacaaa caccaaggag      960

ggauccaaua ucugucugac acggaccgau cgcggcuggu acugcgacaa cgccgggagc     1020

gucucuuucu uuccccaggc ggaaacgugu aaggugcaga gcaauagagu uuucugcgau     1080

acaaugaacu ccagaacccu gccuucugag gugaaucucu gcaacgucga cauuuuuaau     1140

ccgaaauaug auuguaagau caugaccagc aaaacagacg uguccagcuc ugucauuacc     1200

ucccugggag ccaucgugag cugcuacggc aagacaaaau guacggcuuc uaacaagugc     1260

cgggggauua ucaagaccuu cuccaaugga ugugauuaug uuagcaacaa aggcguggac     1320

acagucuccg ugggcaauac ccuuuacuau guuaacaagc aagaggggaa aucucuguac     1380

gugaagggag aacccaucau uaauuuuuau gacccucucg ucuuccccag cgaugaguuu     1440

gacgccucca ucucucaggu gaacgagaaa auuaaccaga gccuggcuuu cauccgcaag     1500

uccgaugaac ugcuccacaa ugugaacgcc ggcaagagca caaccaauau uaugaucacg     1560

accauuauca ucguuauuau cgucauucug cuuucucuga ucgccguggg gcuccugcug     1620

uacugcaaag cuagaugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5926
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5926
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuuu uaauacugaa agcaaaugcc      120

aucacaacca uacuaacugc cgucacauuc ugcuuugcau caggacaaaa cauaacagaa      180

gaauuuuacc aauccacaug cucagcagua ucaaaaggau aucuaucggc acuuagaacu      240

ggaugguaca caaguguuau aacuauagaa cucucaaaca uaaaagaaaa caaaugcaau      300

ggaacagacg caaaaguaaa acuaauaaaa caagaacucg auaaauauaa aaaugcagua      360

accgaacuac aacuauuaau gcaaagcaca cccgcaacag gcagcggauc agcaauagca      420

agcggagucg caguauguaa aguacuacau cuagaaggag aagucaacaa aaucaaaucu      480

gcacuucuau ccacaaacaa agcuguagua ucccuauccg gaugcggagu cucaguauua      540

acuuuuaaag uacuagaccu uaaaaacuac auagauaaac aacuauuacc aauacuaaau      600

aaacaaucau gcagcauauc caauauagag acaguaauug aauuucaaca aaaaaacaac      660

agauuacuag aaauuacucg ugaauuuucc guaaaugccg gagucacaac accaguauca      720

accuauaugc uaacaaacag cgaacuacuu agcuuaauaa augacaugcc aauaacaaau      780

gaccaaaaaa aacuuauguc aaauaacgua caaaucguca gacaacaauc cuacucuaua      840

auguguauaa uuaaagaaga aguccuagca uacguaguuc aauuaccacu cuauggagua      900

auagauacac caugcuggaa acuacacacg ucaccacuau guacaacaaa cacaaaagaa      960

ggauccaaua uaugccuaac aagaaccgac agaggcuggu auugugacaa cgcaggaucc     1020

guuucauucu ucccacaagc agaaaccugu aaaguacaau cuaauagagu auuuugcgac     1080

acaaugaaca guagaacacu accaagcgag guuaaucuau guaacguaga cauauucaau     1140

ccaaaauaug auugcaaaau aaugacauca aaaacagaug uaucgucgag uguaauaaca     1200

agucugggag cuauaguaag cugcuacggc aagacgaaau guaccgcuuc aaauaaaugc     1260

agaggaauca uuaaaacauu cucgaacgga ugcgacuacg uaaguaauaa aggugucgac     1320

accguaucag uagggaauac auuauacuac gucaacaaac aagaaggaaa aucucuauau     1380

guaaaaggag aaccaauaau aaauuucuau gacccucuag uauucccauc agaugaauuu     1440

gacgcuucca uaucacaagu aaacgaaaaa aucaaucaau cuuuagcauu cauacgaaaa     1500

agugaugaac uccuacacaa cgucaacgca ggaaaaagca caacaaauau aaugaucaca     1560

acaaucauca uaguaauaau aguaauacua cuaucauuaa uagcaguagg auuauugcuu     1620

uacugcaaag cacgauaggg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5927
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5927
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacaa uacucaccgc cguaaccuuc ugcuuugcgu cgggacaaaa caucaccgaa      180

gaguucuacc aauccacuug cuccgcagua agcaaaggau accucuccgc ccugcgaacc      240

gguugguaca caucagucau cacaaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg caaaggucaa auuaaucaag caagaacuag acaaauacaa aaacgccguc      360

acagaacucc agcugcuaau gcagagcaca cccgcaacug gcagcggauc cgccaucgca      420

ucaggagucg ccgugugcaa aguccuacac cucgaaggag aagugaacaa aaucaaauca      480

gcccuacucu ccaccaacaa ggccgucguc ucccucuccg gcugcggugu cuccguccua      540

accuucaaag ugcuagaccu caagaacuac aucgacaaac aacuccuacc aauacucaac      600

aagcaaucuu gcuccaucuc caacaucgaa accguaaucg aguuccaaca gaagaacaac      660

cgccuccucg aaaucacccg cgaguucucu gucaacgcag gggucaccac ucccgucucc      720

acauacaugc ucacaaacuc cgaacuccuc agccucauca acgacaugcc cauaaccaac      780

gaccagaaaa agcuaaugag caauaacguc caaaucguua gacaacaaag uuauuccauc      840

augugcauca ucaaagaaga aguccucgcc uacgucguac aacucccccu cuauggcguc      900

aucgacaccc ccugcuggaa acugcacaca ucaccccucu gcaccacaaa caccaaagaa      960

ggcucaaaca ucugccuaac ucgcaccgac cgcggcuggu acugcgacaa cgccggcagc     1020

guaucauucu uuccccaagc cgaaacaugc aaaguucaau ccaaccgcgu cuucugcgac     1080

acaaugaacu ccagaacgcu ccccagcgaa gucaaccucu guaacguaga caucuucaac     1140

ccuaaguacg acugcaaaau caugaccucc aaaacugaug uauccuccuc cgucaucaca     1200

ucccugggcg ccaucgucag cugcuacggc aaaacaaaau gcacugccuc aaacaaaugc     1260

cgagguauca uaaagaccuu cucaaacgga ugcgauuacg ucagcaacaa aggcgucgac     1320

accgucagug ucggcaacac ccucuacuac gucaacaaac aagaaggaaa aucccucuac     1380

gucaaaggcg aacccaucau caacuucuac gacccccucg ucuuccccag cgacgaguuc     1440

gacgccucca ucucacaagu caacgaaaag auaaaccaau cucuagccuu cauccgcaaa     1500

uccgaugaac uccugcauaa cgucaacgcc ggcaaaucca ccacaaacau caugaucacu     1560

accauaauca ucgucauaau cguaauccuc cuaucucuua ucgcagucgg ccuacuacuc     1620

uacugcaaag cccgcuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  5928
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5928
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5929
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5929
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5930
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5930
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5931
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5931
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5932
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5932
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5933
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5933
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5934
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5934
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacugaaagc aaaugccauc acaaccauac      120

uaacugccgu cacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

ccacaugcuc agcaguauca aaaggauauc uaucggcacu uagaacugga ugguacacaa      240

guguuauaac uauagaacuc ucaaacauaa aagaaaacaa augcaaugga acagacgcaa      300

aaguaaaacu aauaaaacaa gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac      360

uauuaaugca aagcacaccc gcaacaggca gcggaucagc aauagcaagc ggagucgcag      420

uauguaaagu acuacaucua gaaggagaag ucaacaaaau caaaucugca cuucuaucca      480

caaacaaagc uguaguaucc cuauccggau gcggagucuc aguauuaacu uuuaaaguac      540

uagaccuuaa aaacuacaua gauaaacaac uauuaccaau acuaaauaaa caaucaugca      600

gcauauccaa uauagagaca guaauugaau uucaacaaaa aaacaacaga uuacuagaaa      660

uuacucguga auuuuccgua aaugccggag ucacaacacc aguaucaacc uauaugcuaa      720

caaacagcga acuacuuagc uuaauaaaug acaugccaau aacaaaugac caaaaaaaac      780

uuaugucaaa uaacguacaa aucgucagac aacaauccua cucuauaaug uguauaauua      840

aagaagaagu ccuagcauac guaguucaau uaccacucua uggaguaaua gauacaccau      900

gcuggaaacu acacacguca ccacuaugua caacaaacac aaaagaagga uccaauauau      960

gccuaacaag aaccgacaga ggcugguauu gugacaacgc aggauccguu ucauucuucc     1020

cacaagcaga aaccuguaaa guacaaucua auagaguauu uugcgacaca augaacagua     1080

gaacacuacc aagcgagguu aaucuaugua acguagacau auucaaucca aaauaugauu     1140

gcaaaauaau gacaucaaaa acagauguau cgucgagugu aauaacaagu cugggagcua     1200

uaguaagcug cuacggcaag acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua     1260

aaacauucuc gaacggaugc gacuacguaa guaauaaagg ugucgacacc guaucaguag     1320

ggaauacauu auacuacguc aacaaacaag aaggaaaauc ucuauaugua aaaggagaac     1380

caauaauaaa uuucuaugac ccucuaguau ucccaucaga ugaauuugac gcuuccauau     1440

cacaaguaaa cgaaaaaauc aaucaaucuu uagcauucau acgaaaaagu gaugaacucc     1500

uacacaacgu caacgcagga aaaagcacaa caaauauaau gaucacaaca aucaucauag     1560

uaauaauagu aauacuacua ucauuaauag caguaggauu auugcuuuac ugcaaagcac     1620

gauagggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5935
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5935
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacaauac      120

ucaccgccgu aaccuucugc uuugcgucgg gacaaaacau caccgaagag uucuaccaau      180

ccacuugcuc cgcaguaagc aaaggauacc ucuccgcccu gcgaaccggu ugguacacau      240

cagucaucac aaucgaacuc ucaaacauaa aagaaaacaa augcaacggc accgacgcaa      300

aggucaaauu aaucaagcaa gaacuagaca aauacaaaaa cgccgucaca gaacuccagc      360

ugcuaaugca gagcacaccc gcaacuggca gcggauccgc caucgcauca ggagucgccg      420

ugugcaaagu ccuacaccuc gaaggagaag ugaacaaaau caaaucagcc cuacucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggugucuc cguccuaacc uucaaagugc      540

uagaccucaa gaacuacauc gacaaacaac uccuaccaau acucaacaag caaucuugcu      600

ccaucuccaa caucgaaacc guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucucuguc aacgcagggg ucaccacucc cgucuccaca uacaugcuca      720

caaacuccga acuccucagc cucaucaacg acaugcccau aaccaacgac cagaaaaagc      780

uaaugagcaa uaacguccaa aucguuagac aacaaaguua uuccaucaug ugcaucauca      840

aagaagaagu ccucgccuac gucguacaac ucccccucua uggcgucauc gacacccccu      900

gcuggaaacu gcacacauca ccccucugca ccacaaacac caaagaaggc ucaaacaucu      960

gccuaacucg caccgaccgc ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc     1020

cccaagccga aacaugcaaa guucaaucca accgcgucuu cugcgacaca augaacucca     1080

gaacgcuccc cagcgaaguc aaccucugua acguagacau cuucaacccu aaguacgacu     1140

gcaaaaucau gaccuccaaa acugauguau ccuccuccgu caucacaucc cugggcgcca     1200

ucgucagcug cuacggcaaa acaaaaugca cugccucaaa caaaugccga gguaucauaa     1260

agaccuucuc aaacggaugc gauuacguca gcaacaaagg cgucgacacc gucagugucg     1320

gcaacacccu cuacuacguc aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac     1380

ccaucaucaa cuucuacgac ccccucgucu uccccagcga cgaguucgac gccuccaucu     1440

cacaagucaa cgaaaagaua aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc     1500

ugcauaacgu caacgccggc aaauccacca caaacaucau gaucacuacc auaaucaucg     1560

ucauaaucgu aauccuccua ucucuuaucg cagucggccu acuacucuac ugcaaagccc     1620

gcuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  5936
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5936
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccaucagcaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ggacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5937
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5937
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggcgagg ugaacaagau caaguccgcc cugcugagca      480

ccaacaaggc cguggucucc cucagcgggu gcggcguguc cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag cagagcugcu      600

ccaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacagcga gcugcugucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccccugua cggcgugauc gacacgccgu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggg uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ggacccuccc cuccgagguc aaccugugca acguggacau cuucaacccg aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggggcca     1200

ucguguccug cuacggcaag accaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg gugagcgugg     1320

ggaacacccu cuacuacguc aacaagcagg agggcaaguc ccuguacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccguggggcu ccugcuguac ugcaaggccc     1620

ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5938
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5938
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccaucuccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

gcacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5939
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5939
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc      360

uucugaugca gucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucuguaaggu guugcaccuc gagggcgaag uuaacaaaau caagagugcu cugcugucca      480

cgaauaaagc cguggucucu cucagcgguu gcgggguguc cguauuaacu uuuaagguuc      540

uggaccuuaa gaacuacauu gauaaacaau ugcugccuau ccuaaauaag cagucaugua      600

guauuagcaa caucgagacc gugauagagu uccagcagaa aaauaacagg cuccuggaaa      660

uuacacggga guuuucuguc aaugcgggag ugacuacccc aguguccaca uauaugcuua      720

ccaacucaga acuguugagc cucaucaaug acaugccgau uacgaacgau caaaagaaac      780

ugaugaguaa caauguccag aucguucgcc agcagucuua cuccaucaug ugcauuauaa      840

aggaggaagu guuagcauau guagugcaac ugccccucua cggcgucauc gacacuccuu      900

guuggaaacu ucauacaagc ccacugugca ccacuaacac aaaggagggc ucgaauauuu      960

guuugacccg aacggaucgu gggugguacu gcgacaacgc cggaucugug uccuucuuuc     1020

cccaggcuga aaccuguaag guucagucaa auagaguguu cugcgauaca augaacagua     1080

gaacucugcc uagcgagguc aaucucugca acguggacau cuuuaaucca aaauaugauu     1140

guaagauaau gaccuccaaa acagacguau cuagcucagu uauuaccagu cugggugcca     1200

ucguguccug cuacggcaag acuaaaugua cagcaagcaa caagugcagg gggaucauua     1260

agaccuucuc uaauggaugu gauuaugucu caaacaaagg cguggacacu gucagugugg     1320

guaauacgcu uuacuauguu aacaagcaag aggggaaaag ccuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccuuugguau ucccauccga ugaguuugac gcuucuauau     1440

cgcaggucaa cgagaaaauc aaccagagcc ucgccuucau ucggaagucc gaugaacugu     1500

uacacaaugu gaacgcgggc aagucaacaa ccaauaucau gaucacuacc auuauaaucg     1560

uuauuaucgu gauucugcua agucucaucg ccgucggccu gcuuuuguac ugcaaagcac     1620

gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5940
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5940
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcaucagcaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagca     1080

gaacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5941
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5941
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccagc      360

ugcugaugca guccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

uguguaaggu ucuccaccug gagggggaag ugaacaaaau caagagcgcc cuucugucua      480

ccaauaaagc ugucgugucc cucagcggau gcggcguuuc ugugcugaca uuuaaggucc      540

uugaccugaa gaacuacauu gauaaacaac uccugccuau ccugaauaag caguccugua      600

gcauuucuaa caucgagacc gugauugagu uccagcagaa aaauaaccgg cuccuggaaa      660

ucacgcgcga guuuuccgug aaugccggcg ucacaacccc gguuagcaca uauaugcuua      720

ccaacuccga acugcucucu cugaucaaug acaugcccau uaccaacgau caaaagaaac      780

uuaugagcaa caaugugcag aucgugagac agcaguccua cagcauuaug ugcaucauua      840

aggaggaagu ccuggcuuau gugguucaac ucccucugua cggggugauc gacacacccu      900

guuggaaacu gcauacgucu ccucucugca ccacaaacac caaggaggga uccaauaucu      960

gucugacacg gaccgaucgc ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc     1020

cccaggcgga aacguguaag gugcagagca auagaguuuu cugcgauaca augaacucca     1080

gaacccugcc uucugaggug aaucucugca acgucgacau uuuuaauccg aaauaugauu     1140

guaagaucau gaccagcaaa acagacgugu ccagcucugu cauuaccucc cugggagcca     1200

ucgugagcug cuacggcaag acaaaaugua cggcuucuaa caagugccgg gggauuauca     1260

agaccuucuc caauggaugu gauuauguua gcaacaaagg cguggacaca gucuccgugg     1320

gcaauacccu uuacuauguu aacaagcaag aggggaaauc ucuguacgug aagggagaac     1380

ccaucauuaa uuuuuaugac ccucucgucu uccccagcga ugaguuugac gccuccaucu     1440

cucaggugaa cgagaaaauu aaccagagcc uggcuuucau ccgcaagucc gaugaacugc     1500

uccacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc auuaucaucg     1560

uuauuaucgu cauucugcuu ucucugaucg ccguggggcu ccugcuguac ugcaaagcua     1620

gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5942
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5942
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuuuuaa uacugaaagc aaaugccauc acaaccauac      120

uaacugccgu cacauucugc uuugcaucag gacaaaacau aacagaagaa uuuuaccaau      180

ccacaugcuc agcaguauca aaaggauauc uaucggcacu uagaacugga ugguacacaa      240

guguuauaac uauagaacuc ucaaacauaa aagaaaacaa augcaaugga acagacgcaa      300

aaguaaaacu aauaaaacaa gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac      360

uauuaaugca aagcacaccc gcaacaggca gcggaucagc aauagcaagc ggagucgcag      420

uauguaaagu acuacaucua gaaggagaag ucaacaaaau caaaucugca cuucuaucca      480

caaacaaagc uguaguaucc cuauccggau gcggagucuc aguauuaacu uuuaaaguac      540

uagaccuuaa aaacuacaua gauaaacaac uauuaccaau acuaaauaaa caaucaugca      600

gcauauccaa uauagagaca guaauugaau uucaacaaaa aaacaacaga uuacuagaaa      660

uuacucguga auuuuccgua aaugccggag ucacaacacc aguaucaacc uauaugcuaa      720

caaacagcga acuacuuagc uuaauaaaug acaugccaau aacaaaugac caaaaaaaac      780

uuaugucaaa uaacguacaa aucgucagac aacaauccua cucuauaaug uguauaauua      840

aagaagaagu ccuagcauac guaguucaau uaccacucua uggaguaaua gauacaccau      900

gcuggaaacu acacacguca ccacuaugua caacaaacac aaaagaagga uccaauauau      960

gccuaacaag aaccgacaga ggcugguauu gugacaacgc aggauccguu ucauucuucc     1020

cacaagcaga aaccuguaaa guacaaucua auagaguauu uugcgacaca augaacagua     1080

gaacacuacc aagcgagguu aaucuaugua acguagacau auucaaucca aaauaugauu     1140

gcaaaauaau gacaucaaaa acagauguau cgucgagugu aauaacaagu cugggagcua     1200

uaguaagcug cuacggcaag acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua     1260

aaacauucuc gaacggaugc gacuacguaa guaauaaagg ugucgacacc guaucaguag     1320

ggaauacauu auacuacguc aacaaacaag aaggaaaauc ucuauaugua aaaggagaac     1380

caauaauaaa uuucuaugac ccucuaguau ucccaucaga ugaauuugac gcuuccauau     1440

cacaaguaaa cgaaaaaauc aaucaaucuu uagcauucau acgaaaaagu gaugaacucc     1500

uacacaacgu caacgcagga aaaagcacaa caaauauaau gaucacaaca aucaucauag     1560

uaauaauagu aauacuacua ucauuaauag caguaggauu auugcuuuac ugcaaagcac     1620

gauagggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5943
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5943
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacaauac      120

ucaccgccgu aaccuucugc uuugcgucgg gacaaaacau caccgaagag uucuaccaau      180

ccacuugcuc cgcaguaagc aaaggauacc ucuccgcccu gcgaaccggu ugguacacau      240

cagucaucac aaucgaacuc ucaaacauaa aagaaaacaa augcaacggc accgacgcaa      300

aggucaaauu aaucaagcaa gaacuagaca aauacaaaaa cgccgucaca gaacuccagc      360

ugcuaaugca gagcacaccc gcaacuggca gcggauccgc caucgcauca ggagucgccg      420

ugugcaaagu ccuacaccuc gaaggagaag ugaacaaaau caaaucagcc cuacucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggugucuc cguccuaacc uucaaagugc      540

uagaccucaa gaacuacauc gacaaacaac uccuaccaau acucaacaag caaucuugcu      600

ccaucuccaa caucgaaacc guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucucuguc aacgcagggg ucaccacucc cgucuccaca uacaugcuca      720

caaacuccga acuccucagc cucaucaacg acaugcccau aaccaacgac cagaaaaagc      780

uaaugagcaa uaacguccaa aucguuagac aacaaaguua uuccaucaug ugcaucauca      840

aagaagaagu ccucgccuac gucguacaac ucccccucua uggcgucauc gacacccccu      900

gcuggaaacu gcacacauca ccccucugca ccacaaacac caaagaaggc ucaaacaucu      960

gccuaacucg caccgaccgc ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc     1020

cccaagccga aacaugcaaa guucaaucca accgcgucuu cugcgacaca augaacucca     1080

gaacgcuccc cagcgaaguc aaccucugua acguagacau cuucaacccu aaguacgacu     1140

gcaaaaucau gaccuccaaa acugauguau ccuccuccgu caucacaucc cugggcgcca     1200

ucgucagcug cuacggcaaa acaaaaugca cugccucaaa caaaugccga gguaucauaa     1260

agaccuucuc aaacggaugc gauuacguca gcaacaaagg cgucgacacc gucagugucg     1320

gcaacacccu cuacuacguc aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac     1380

ccaucaucaa cuucuacgac ccccucgucu uccccagcga cgaguucgac gccuccaucu     1440

cacaagucaa cgaaaagaua aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc     1500

ugcauaacgu caacgccggc aaauccacca caaacaucau gaucacuacc auaaucaucg     1560

ucauaaucgu aauccuccua ucucuuaucg cagucggccu acuacucuac ugcaaagccc     1620

gcuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  5944
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5944
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5945
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5945
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccggugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5946
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5946
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5947
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5947
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5948
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5948
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5949
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5949
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagaugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5950
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5950
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacugaaa gcaaaugcca ucacaaccau acuaacugcc      120

gucacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca auccacaugc      180

ucagcaguau caaaaggaua ucuaucggca cuuagaacug gaugguacac aaguguuaua      240

acuauagaac ucucaaacau aaaagaaaac aaaugcaaug gaacagacgc aaaaguaaaa      300

cuaauaaaac aagaacucga uaaauauaaa aaugcaguaa ccgaacuaca acuauuaaug      360

caaagcacac ccgcaacagg cagcggauca gcaauagcaa gcggagucgc aguauguaaa      420

guacuacauc uagaaggaga agucaacaaa aucaaaucug cacuucuauc cacaaacaaa      480

gcuguaguau cccuauccgg augcggaguc ucaguauuaa cuuuuaaagu acuagaccuu      540

aaaaacuaca uagauaaaca acuauuacca auacuaaaua aacaaucaug cagcauaucc      600

aauauagaga caguaauuga auuucaacaa aaaaacaaca gauuacuaga aauuacucgu      660

gaauuuuccg uaaaugccgg agucacaaca ccaguaucaa ccuauaugcu aacaaacagc      720

gaacuacuua gcuuaauaaa ugacaugcca auaacaaaug accaaaaaaa acuuauguca      780

aauaacguac aaaucgucag acaacaaucc uacucuauaa uguguauaau uaaagaagaa      840

guccuagcau acguaguuca auuaccacuc uauggaguaa uagauacacc augcuggaaa      900

cuacacacgu caccacuaug uacaacaaac acaaaagaag gauccaauau augccuaaca      960

agaaccgaca gaggcuggua uugugacaac gcaggauccg uuucauucuu cccacaagca     1020

gaaaccugua aaguacaauc uaauagagua uuuugcgaca caaugaacag uagaacacua     1080

ccaagcgagg uuaaucuaug uaacguagac auauucaauc caaaauauga uugcaaaaua     1140

augacaucaa aaacagaugu aucgucgagu guaauaacaa gucugggagc uauaguaagc     1200

ugcuacggca agacgaaaug uaccgcuuca aauaaaugca gaggaaucau uaaaacauuc     1260

ucgaacggau gcgacuacgu aaguaauaaa ggugucgaca ccguaucagu agggaauaca     1320

uuauacuacg ucaacaaaca agaaggaaaa ucucuauaug uaaaaggaga accaauaaua     1380

aauuucuaug acccucuagu auucccauca gaugaauuug acgcuuccau aucacaagua     1440

aacgaaaaaa ucaaucaauc uuuagcauuc auacgaaaaa gugaugaacu ccuacacaac     1500

gucaacgcag gaaaaagcac aacaaauaua augaucacaa caaucaucau aguaauaaua     1560

guaauacuac uaucauuaau agcaguagga uuauugcuuu acugcaaagc acgauaggga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5951
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5951
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacaau acucaccgcc      120

guaaccuucu gcuuugcguc gggacaaaac aucaccgaag aguucuacca auccacuugc      180

uccgcaguaa gcaaaggaua ccucuccgcc cugcgaaccg guugguacac aucagucauc      240

acaaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcaccgacgc aaaggucaaa      300

uuaaucaagc aagaacuaga caaauacaaa aacgccguca cagaacucca gcugcuaaug      360

cagagcacac ccgcaacugg cagcggaucc gccaucgcau caggagucgc cgugugcaaa      420

guccuacacc ucgaaggaga agugaacaaa aucaaaucag cccuacucuc caccaacaag      480

gccgucgucu cccucuccgg cugcgguguc uccguccuaa ccuucaaagu gcuagaccuc      540

aagaacuaca ucgacaaaca acuccuacca auacucaaca agcaaucuug cuccaucucc      600

aacaucgaaa ccguaaucga guuccaacag aagaacaacc gccuccucga aaucacccgc      660

gaguucucug ucaacgcagg ggucaccacu cccgucucca cauacaugcu cacaaacucc      720

gaacuccuca gccucaucaa cgacaugccc auaaccaacg accagaaaaa gcuaaugagc      780

aauaacgucc aaaucguuag acaacaaagu uauuccauca ugugcaucau caaagaagaa      840

guccucgccu acgucguaca acucccccuc uauggcguca ucgacacccc cugcuggaaa      900

cugcacacau caccccucug caccacaaac accaaagaag gcucaaacau cugccuaacu      960

cgcaccgacc gcggcuggua cugcgacaac gccggcagcg uaucauucuu uccccaagcc     1020

gaaacaugca aaguucaauc caaccgcguc uucugcgaca caaugaacuc cagaacgcuc     1080

cccagcgaag ucaaccucug uaacguagac aucuucaacc cuaaguacga cugcaaaauc     1140

augaccucca aaacugaugu auccuccucc gucaucacau cccugggcgc caucgucagc     1200

ugcuacggca aaacaaaaug cacugccuca aacaaaugcc gagguaucau aaagaccuuc     1260

ucaaacggau gcgauuacgu cagcaacaaa ggcgucgaca ccgucagugu cggcaacacc     1320

cucuacuacg ucaacaaaca agaaggaaaa ucccucuacg ucaaaggcga acccaucauc     1380

aacuucuacg acccccucgu cuuccccagc gacgaguucg acgccuccau cucacaaguc     1440

aacgaaaaga uaaaccaauc ucuagccuuc auccgcaaau ccgaugaacu ccugcauaac     1500

gucaacgccg gcaaauccac cacaaacauc augaucacua ccauaaucau cgucauaauc     1560

guaauccucc uaucucuuau cgcagucggc cuacuacucu acugcaaagc ccgcuaagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  5952
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5952
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucagc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccggacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5953
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5953
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gcuccugaug      360

caguccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc ucgagggcga ggugaacaag aucaaguccg cccugcugag caccaacaag      480

gccguggucu cccucagcgg gugcggcgug uccgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcagagcug cuccaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg ggucaccacg cccgugagca ccuacaugcu caccaacagc      720

gagcugcugu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccccug uacggcguga ucgacacgcc gugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gguccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggcuccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccggacccuc     1080

cccuccgagg ucaaccugug caacguggac aucuucaacc cgaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggggc caucgugucc     1200

ugcuacggca agaccaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcgucgaca cggugagcgu ggggaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccuguacg ugaaggggga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggg cuccugcugu acugcaaggc ccggugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5954
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5954
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucucc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccgcacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggcaag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5955
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5955
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gcuucugaug      360

cagucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucuguaag      420

guguugcacc ucgagggcga aguuaacaaa aucaagagug cucugcuguc cacgaauaaa      480

gccguggucu cucucagcgg uugcggggug uccguauuaa cuuuuaaggu ucuggaccuu      540

aagaacuaca uugauaaaca auugcugccu auccuaaaua agcagucaug uaguauuagc      600

aacaucgaga ccgugauaga guuccagcag aaaaauaaca ggcuccugga aauuacacgg      660

gaguuuucug ucaaugcggg agugacuacc ccagugucca cauauaugcu uaccaacuca      720

gaacuguuga gccucaucaa ugacaugccg auuacgaacg aucaaaagaa acugaugagu      780

aacaaugucc agaucguucg ccagcagucu uacuccauca ugugcauuau aaaggaggaa      840

guguuagcau auguagugca acugccccuc uacggcguca ucgacacucc uuguuggaaa      900

cuucauacaa gcccacugug caccacuaac acaaaggagg gcucgaauau uuguuugacc      960

cgaacggauc guggguggua cugcgacaac gccggaucug uguccuucuu uccccaggcu     1020

gaaaccugua agguucaguc aaauagagug uucugcgaua caaugaacag uagaacucug     1080

ccuagcgagg ucaaucucug caacguggac aucuuuaauc caaaauauga uuguaagaua     1140

augaccucca aaacagacgu aucuagcuca guuauuacca gucugggugc caucgugucc     1200

ugcuacggca agacuaaaug uacagcaagc aacaagugca gggggaucau uaagaccuuc     1260

ucuaauggau gugauuaugu cucaaacaaa ggcguggaca cugucagugu ggguaauacg     1320

cuuuacuaug uuaacaagca agaggggaaa agccuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccuuuggu auucccaucc gaugaguuug acgcuucuau aucgcagguc     1440

aacgagaaaa ucaaccagag ccucgccuuc auucggaagu ccgaugaacu guuacacaau     1500

gugaacgcgg gcaagucaac aaccaauauc augaucacua ccauuauaau cguuauuauc     1560

gugauucugc uaagucucau cgccgucggc cugcuuuugu acugcaaagc acgcugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5956
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5956
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucagc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag cagaacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggcaag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5957
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5957
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gcugcugaug      360

caguccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc gguguguaag      420

guucuccacc uggaggggga agugaacaaa aucaagagcg cccuucuguc uaccaauaaa      480

gcugucgugu cccucagcgg augcggcguu ucugugcuga cauuuaaggu ccuugaccug      540

aagaacuaca uugauaaaca acuccugccu auccugaaua agcaguccug uagcauuucu      600

aacaucgaga ccgugauuga guuccagcag aaaaauaacc ggcuccugga aaucacgcgc      660

gaguuuuccg ugaaugccgg cgucacaacc ccgguuagca cauauaugcu uaccaacucc      720

gaacugcucu cucugaucaa ugacaugccc auuaccaacg aucaaaagaa acuuaugagc      780

aacaaugugc agaucgugag acagcagucc uacagcauua ugugcaucau uaaggaggaa      840

guccuggcuu augugguuca acucccucug uacgggguga ucgacacacc cuguuggaaa      900

cugcauacgu cuccucucug caccacaaac accaaggagg gauccaauau cugucugaca      960

cggaccgauc gcggcuggua cugcgacaac gccgggagcg ucucuuucuu uccccaggcg     1020

gaaacgugua aggugcagag caauagaguu uucugcgaua caaugaacuc cagaacccug     1080

ccuucugagg ugaaucucug caacgucgac auuuuuaauc cgaaauauga uuguaagauc     1140

augaccagca aaacagacgu guccagcucu gucauuaccu cccugggagc caucgugagc     1200

ugcuacggca agacaaaaug uacggcuucu aacaagugcc gggggauuau caagaccuuc     1260

uccaauggau gugauuaugu uagcaacaaa ggcguggaca cagucuccgu gggcaauacc     1320

cuuuacuaug uuaacaagca agaggggaaa ucucuguacg ugaagggaga acccaucauu     1380

aauuuuuaug acccucucgu cuuccccagc gaugaguuug acgccuccau cucucaggug     1440

aacgagaaaa uuaaccagag ccuggcuuuc auccgcaagu ccgaugaacu gcuccacaau     1500

gugaacgccg gcaagagcac aaccaauauu augaucacga ccauuaucau cguuauuauc     1560

gucauucugc uuucucugau cgccgugggg cuccugcugu acugcaaagc uagaugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5958
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5958
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuuuu aauacugaaa gcaaaugcca ucacaaccau acuaacugcc      120

gucacauucu gcuuugcauc aggacaaaac auaacagaag aauuuuacca auccacaugc      180

ucagcaguau caaaaggaua ucuaucggca cuuagaacug gaugguacac aaguguuaua      240

acuauagaac ucucaaacau aaaagaaaac aaaugcaaug gaacagacgc aaaaguaaaa      300

cuaauaaaac aagaacucga uaaauauaaa aaugcaguaa ccgaacuaca acuauuaaug      360

caaagcacac ccgcaacagg cagcggauca gcaauagcaa gcggagucgc aguauguaaa      420

guacuacauc uagaaggaga agucaacaaa aucaaaucug cacuucuauc cacaaacaaa      480

gcuguaguau cccuauccgg augcggaguc ucaguauuaa cuuuuaaagu acuagaccuu      540

aaaaacuaca uagauaaaca acuauuacca auacuaaaua aacaaucaug cagcauaucc      600

aauauagaga caguaauuga auuucaacaa aaaaacaaca gauuacuaga aauuacucgu      660

gaauuuuccg uaaaugccgg agucacaaca ccaguaucaa ccuauaugcu aacaaacagc      720

gaacuacuua gcuuaauaaa ugacaugcca auaacaaaug accaaaaaaa acuuauguca      780

aauaacguac aaaucgucag acaacaaucc uacucuauaa uguguauaau uaaagaagaa      840

guccuagcau acguaguuca auuaccacuc uauggaguaa uagauacacc augcuggaaa      900

cuacacacgu caccacuaug uacaacaaac acaaaagaag gauccaauau augccuaaca      960

agaaccgaca gaggcuggua uugugacaac gcaggauccg uuucauucuu cccacaagca     1020

gaaaccugua aaguacaauc uaauagagua uuuugcgaca caaugaacag uagaacacua     1080

ccaagcgagg uuaaucuaug uaacguagac auauucaauc caaaauauga uugcaaaaua     1140

augacaucaa aaacagaugu aucgucgagu guaauaacaa gucugggagc uauaguaagc     1200

ugcuacggca agacgaaaug uaccgcuuca aauaaaugca gaggaaucau uaaaacauuc     1260

ucgaacggau gcgacuacgu aaguaauaaa ggugucgaca ccguaucagu agggaauaca     1320

uuauacuacg ucaacaaaca agaaggaaaa ucucuauaug uaaaaggaga accaauaaua     1380

aauuucuaug acccucuagu auucccauca gaugaauuug acgcuuccau aucacaagua     1440

aacgaaaaaa ucaaucaauc uuuagcauuc auacgaaaaa gugaugaacu ccuacacaac     1500

gucaacgcag gaaaaagcac aacaaauaua augaucacaa caaucaucau aguaauaaua     1560

guaauacuac uaucauuaau agcaguagga uuauugcuuu acugcaaagc acgauaggga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5959
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5959
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacaau acucaccgcc      120

guaaccuucu gcuuugcguc gggacaaaac aucaccgaag aguucuacca auccacuugc      180

uccgcaguaa gcaaaggaua ccucuccgcc cugcgaaccg guugguacac aucagucauc      240

acaaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcaccgacgc aaaggucaaa      300

uuaaucaagc aagaacuaga caaauacaaa aacgccguca cagaacucca gcugcuaaug      360

cagagcacac ccgcaacugg cagcggaucc gccaucgcau caggagucgc cgugugcaaa      420

guccuacacc ucgaaggaga agugaacaaa aucaaaucag cccuacucuc caccaacaag      480

gccgucgucu cccucuccgg cugcgguguc uccguccuaa ccuucaaagu gcuagaccuc      540

aagaacuaca ucgacaaaca acuccuacca auacucaaca agcaaucuug cuccaucucc      600

aacaucgaaa ccguaaucga guuccaacag aagaacaacc gccuccucga aaucacccgc      660

gaguucucug ucaacgcagg ggucaccacu cccgucucca cauacaugcu cacaaacucc      720

gaacuccuca gccucaucaa cgacaugccc auaaccaacg accagaaaaa gcuaaugagc      780

aauaacgucc aaaucguuag acaacaaagu uauuccauca ugugcaucau caaagaagaa      840

guccucgccu acgucguaca acucccccuc uauggcguca ucgacacccc cugcuggaaa      900

cugcacacau caccccucug caccacaaac accaaagaag gcucaaacau cugccuaacu      960

cgcaccgacc gcggcuggua cugcgacaac gccggcagcg uaucauucuu uccccaagcc     1020

gaaacaugca aaguucaauc caaccgcguc uucugcgaca caaugaacuc cagaacgcuc     1080

cccagcgaag ucaaccucug uaacguagac aucuucaacc cuaaguacga cugcaaaauc     1140

augaccucca aaacugaugu auccuccucc gucaucacau cccugggcgc caucgucagc     1200

ugcuacggca aaacaaaaug cacugccuca aacaaaugcc gagguaucau aaagaccuuc     1260

ucaaacggau gcgauuacgu cagcaacaaa ggcgucgaca ccgucagugu cggcaacacc     1320

cucuacuacg ucaacaaaca agaaggaaaa ucccucuacg ucaaaggcga acccaucauc     1380

aacuucuacg acccccucgu cuuccccagc gacgaguucg acgccuccau cucacaaguc     1440

aacgaaaaga uaaaccaauc ucuagccuuc auccgcaaau ccgaugaacu ccugcauaac     1500

gucaacgccg gcaaauccac cacaaacauc augaucacua ccauaaucau cgucauaauc     1560

guaauccucc uaucucuuau cgcagucggc cuacuacucu acugcaaagc ccgcuaagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  5960
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5960
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5961
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5961
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5962
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5962
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5963
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5963
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5964
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5964
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5965
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5965
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5966
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5966
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acugaaagca      120

aaugccauca caaccauacu aacugccguc acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc cacaugcuca gcaguaucaa aaggauaucu aucggcacuu      240

agaacuggau gguacacaag uguuauaacu auagaacucu caaacauaaa agaaaacaaa      300

ugcaauggaa cagacgcaaa aguaaaacua auaaaacaag aacucgauaa auauaaaaau      360

gcaguaaccg aacuacaacu auuaaugcaa agcacacccg caacaggcag cggaucagca      420

auagcaagcg gagucgcagu auguaaagua cuacaucuag aaggagaagu caacaaaauc      480

aaaucugcac uucuauccac aaacaaagcu guaguauccc uauccggaug cggagucuca      540

guauuaacuu uuaaaguacu agaccuuaaa aacuacauag auaaacaacu auuaccaaua      600

cuaaauaaac aaucaugcag cauauccaau auagagacag uaauugaauu ucaacaaaaa      660

aacaacagau uacuagaaau uacucgugaa uuuuccguaa augccggagu cacaacacca      720

guaucaaccu auaugcuaac aaacagcgaa cuacuuagcu uaauaaauga caugccaaua      780

acaaaugacc aaaaaaaacu uaugucaaau aacguacaaa ucgucagaca acaauccuac      840

ucuauaaugu guauaauuaa agaagaaguc cuagcauacg uaguucaauu accacucuau      900

ggaguaauag auacaccaug cuggaaacua cacacgucac cacuauguac aacaaacaca      960

aaagaaggau ccaauauaug ccuaacaaga accgacagag gcugguauug ugacaacgca     1020

ggauccguuu cauucuuccc acaagcagaa accuguaaag uacaaucuaa uagaguauuu     1080

ugcgacacaa ugaacaguag aacacuacca agcgagguua aucuauguaa cguagacaua     1140

uucaauccaa aauaugauug caaaauaaug acaucaaaaa cagauguauc gucgagugua     1200

auaacaaguc ugggagcuau aguaagcugc uacggcaaga cgaaauguac cgcuucaaau     1260

aaaugcagag gaaucauuaa aacauucucg aacggaugcg acuacguaag uaauaaaggu     1320

gucgacaccg uaucaguagg gaauacauua uacuacguca acaaacaaga aggaaaaucu     1380

cuauauguaa aaggagaacc aauaauaaau uucuaugacc cucuaguauu cccaucagau     1440

gaauuugacg cuuccauauc acaaguaaac gaaaaaauca aucaaucuuu agcauucaua     1500

cgaaaaagug augaacuccu acacaacguc aacgcaggaa aaagcacaac aaauauaaug     1560

aucacaacaa ucaucauagu aauaauagua auacuacuau cauuaauagc aguaggauua     1620

uugcuuuacu gcaaagcacg auagggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5967
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5967
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacaauacu caccgccgua accuucugcu uugcgucggg acaaaacauc      180

accgaagagu ucuaccaauc cacuugcucc gcaguaagca aaggauaccu cuccgcccug      240

cgaaccgguu gguacacauc agucaucaca aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa ggucaaauua aucaagcaag aacuagacaa auacaaaaac      360

gccgucacag aacuccagcu gcuaaugcag agcacacccg caacuggcag cggauccgcc      420

aucgcaucag gagucgccgu gugcaaaguc cuacaccucg aaggagaagu gaacaaaauc      480

aaaucagccc uacucuccac caacaaggcc gucgucuccc ucuccggcug cggugucucc      540

guccuaaccu ucaaagugcu agaccucaag aacuacaucg acaaacaacu ccuaccaaua      600

cucaacaagc aaucuugcuc caucuccaac aucgaaaccg uaaucgaguu ccaacagaag      660

aacaaccgcc uccucgaaau cacccgcgag uucucuguca acgcaggggu caccacuccc      720

gucuccacau acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugcccaua      780

accaacgacc agaaaaagcu aaugagcaau aacguccaaa ucguuagaca acaaaguuau      840

uccaucaugu gcaucaucaa agaagaaguc cucgccuacg ucguacaacu cccccucuau      900

ggcgucaucg acacccccug cuggaaacug cacacaucac cccucugcac cacaaacacc      960

aaagaaggcu caaacaucug ccuaacucgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcagcguau cauucuuucc ccaagccgaa acaugcaaag uucaauccaa ccgcgucuuc     1080

ugcgacacaa ugaacuccag aacgcucccc agcgaaguca accucuguaa cguagacauc     1140

uucaacccua aguacgacug caaaaucaug accuccaaaa cugauguauc cuccuccguc     1200

aucacauccc ugggcgccau cgucagcugc uacggcaaaa caaaaugcac ugccucaaac     1260

aaaugccgag guaucauaaa gaccuucuca aacggaugcg auuacgucag caacaaaggc     1320

gucgacaccg ucagugucgg caacacccuc uacuacguca acaaacaaga aggaaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagcgac     1440

gaguucgacg ccuccaucuc acaagucaac gaaaagauaa accaaucucu agccuucauc     1500

cgcaaauccg augaacuccu gcauaacguc aacgccggca aauccaccac aaacaucaug     1560

aucacuacca uaaucaucgu cauaaucgua auccuccuau cucuuaucgc agucggccua     1620

cuacucuacu gcaaagcccg cuaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  5968
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5968
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccg gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5969
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5969
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagcu ccugaugcag uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccucg agggcgaggu gaacaagauc      480

aaguccgccc ugcugagcac caacaaggcc guggucuccc ucagcgggug cggcgugucc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc agagcugcuc caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcucac caacagcgag cugcuguccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccccuguac      900

ggcgugaucg acacgccgug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggaggggu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccg gacccucccc uccgagguca accugugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg gaacacccuc uacuacguca acaagcagga gggcaagucc     1380

cuguacguga agggggagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cguggggcuc     1620

cugcuguacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5970
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5970
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccg cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5971
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5971
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagcu ucugaugcag ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cuguaaggug uugcaccucg agggcgaagu uaacaaaauc      480

aagagugcuc ugcuguccac gaauaaagcc guggucucuc ucagcgguug cggggugucc      540

guauuaacuu uuaagguucu ggaccuuaag aacuacauug auaaacaauu gcugccuauc      600

cuaaauaagc agucauguag uauuagcaac aucgagaccg ugauagaguu ccagcagaaa      660

aauaacaggc uccuggaaau uacacgggag uuuucuguca augcgggagu gacuacccca      720

guguccacau auaugcuuac caacucagaa cuguugagcc ucaucaauga caugccgauu      780

acgaacgauc aaaagaaacu gaugaguaac aauguccaga ucguucgcca gcagucuuac      840

uccaucaugu gcauuauaaa ggaggaagug uuagcauaug uagugcaacu gccccucuac      900

ggcgucaucg acacuccuug uuggaaacuu cauacaagcc cacugugcac cacuaacaca      960

aaggagggcu cgaauauuug uuugacccga acggaucgug ggugguacug cgacaacgcc     1020

ggaucugugu ccuucuuucc ccaggcugaa accuguaagg uucagucaaa uagaguguuc     1080

ugcgauacaa ugaacaguag aacucugccu agcgagguca aucucugcaa cguggacauc     1140

uuuaauccaa aauaugauug uaagauaaug accuccaaaa cagacguauc uagcucaguu     1200

auuaccaguc ugggugccau cguguccugc uacggcaaga cuaaauguac agcaagcaac     1260

aagugcaggg ggaucauuaa gaccuucucu aauggaugug auuaugucuc aaacaaaggc     1320

guggacacug ucaguguggg uaauacgcuu uacuauguua acaagcaaga ggggaaaagc     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cuuugguauu cccauccgau     1440

gaguuugacg cuucuauauc gcaggucaac gagaaaauca accagagccu cgccuucauu     1500

cggaaguccg augaacuguu acacaaugug aacgcgggca agucaacaac caauaucaug     1560

aucacuacca uuauaaucgu uauuaucgug auucugcuaa gucucaucgc cgucggccug     1620

cuuuuguacu gcaaagcacg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5972
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5972
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagcag aacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5973
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5973
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagcu gcugaugcag uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu guguaagguu cuccaccugg agggggaagu gaacaaaauc      480

aagagcgccc uucugucuac caauaaagcu gucguguccc ucagcggaug cggcguuucu      540

gugcugacau uuaagguccu ugaccugaag aacuacauug auaaacaacu ccugccuauc      600

cugaauaagc aguccuguag cauuucuaac aucgagaccg ugauugaguu ccagcagaaa      660

aauaaccggc uccuggaaau cacgcgcgag uuuuccguga augccggcgu cacaaccccg      720

guuagcacau auaugcuuac caacuccgaa cugcucucuc ugaucaauga caugcccauu      780

accaacgauc aaaagaaacu uaugagcaac aaugugcaga ucgugagaca gcaguccuac      840

agcauuaugu gcaucauuaa ggaggaaguc cuggcuuaug ugguucaacu cccucuguac      900

ggggugaucg acacacccug uuggaaacug cauacgucuc cucucugcac cacaaacacc      960

aaggagggau ccaauaucug ucugacacgg accgaucgcg gcugguacug cgacaacgcc     1020

gggagcgucu cuuucuuucc ccaggcggaa acguguaagg ugcagagcaa uagaguuuuc     1080

ugcgauacaa ugaacuccag aacccugccu ucugagguga aucucugcaa cgucgacauu     1140

uuuaauccga aauaugauug uaagaucaug accagcaaaa cagacguguc cagcucuguc     1200

auuaccuccc ugggagccau cgugagcugc uacggcaaga caaaauguac ggcuucuaac     1260

aagugccggg ggauuaucaa gaccuucucc aauggaugug auuauguuag caacaaaggc     1320

guggacacag ucuccguggg caauacccuu uacuauguua acaagcaaga ggggaaaucu     1380

cuguacguga agggagaacc caucauuaau uuuuaugacc cucucgucuu ccccagcgau     1440

gaguuugacg ccuccaucuc ucaggugaac gagaaaauua accagagccu ggcuuucauc     1500

cgcaaguccg augaacugcu ccacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucaucgu uauuaucguc auucugcuuu cucugaucgc cguggggcuc     1620

cugcuguacu gcaaagcuag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5974
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5974
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuuuuaau acugaaagca      120

aaugccauca caaccauacu aacugccguc acauucugcu uugcaucagg acaaaacaua      180

acagaagaau uuuaccaauc cacaugcuca gcaguaucaa aaggauaucu aucggcacuu      240

agaacuggau gguacacaag uguuauaacu auagaacucu caaacauaaa agaaaacaaa      300

ugcaauggaa cagacgcaaa aguaaaacua auaaaacaag aacucgauaa auauaaaaau      360

gcaguaaccg aacuacaacu auuaaugcaa agcacacccg caacaggcag cggaucagca      420

auagcaagcg gagucgcagu auguaaagua cuacaucuag aaggagaagu caacaaaauc      480

aaaucugcac uucuauccac aaacaaagcu guaguauccc uauccggaug cggagucuca      540

guauuaacuu uuaaaguacu agaccuuaaa aacuacauag auaaacaacu auuaccaaua      600

cuaaauaaac aaucaugcag cauauccaau auagagacag uaauugaauu ucaacaaaaa      660

aacaacagau uacuagaaau uacucgugaa uuuuccguaa augccggagu cacaacacca      720

guaucaaccu auaugcuaac aaacagcgaa cuacuuagcu uaauaaauga caugccaaua      780

acaaaugacc aaaaaaaacu uaugucaaau aacguacaaa ucgucagaca acaauccuac      840

ucuauaaugu guauaauuaa agaagaaguc cuagcauacg uaguucaauu accacucuau      900

ggaguaauag auacaccaug cuggaaacua cacacgucac cacuauguac aacaaacaca      960

aaagaaggau ccaauauaug ccuaacaaga accgacagag gcugguauug ugacaacgca     1020

ggauccguuu cauucuuccc acaagcagaa accuguaaag uacaaucuaa uagaguauuu     1080

ugcgacacaa ugaacaguag aacacuacca agcgagguua aucuauguaa cguagacaua     1140

uucaauccaa aauaugauug caaaauaaug acaucaaaaa cagauguauc gucgagugua     1200

auaacaaguc ugggagcuau aguaagcugc uacggcaaga cgaaauguac cgcuucaaau     1260

aaaugcagag gaaucauuaa aacauucucg aacggaugcg acuacguaag uaauaaaggu     1320

gucgacaccg uaucaguagg gaauacauua uacuacguca acaaacaaga aggaaaaucu     1380

cuauauguaa aaggagaacc aauaauaaau uucuaugacc cucuaguauu cccaucagau     1440

gaauuugacg cuuccauauc acaaguaaac gaaaaaauca aucaaucuuu agcauucaua     1500

cgaaaaagug augaacuccu acacaacguc aacgcaggaa aaagcacaac aaauauaaug     1560

aucacaacaa ucaucauagu aauaauagua auacuacuau cauuaauagc aguaggauua     1620

uugcuuuacu gcaaagcacg auagggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5975
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5975
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacaauacu caccgccgua accuucugcu uugcgucggg acaaaacauc      180

accgaagagu ucuaccaauc cacuugcucc gcaguaagca aaggauaccu cuccgcccug      240

cgaaccgguu gguacacauc agucaucaca aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca ccgacgcaaa ggucaaauua aucaagcaag aacuagacaa auacaaaaac      360

gccgucacag aacuccagcu gcuaaugcag agcacacccg caacuggcag cggauccgcc      420

aucgcaucag gagucgccgu gugcaaaguc cuacaccucg aaggagaagu gaacaaaauc      480

aaaucagccc uacucuccac caacaaggcc gucgucuccc ucuccggcug cggugucucc      540

guccuaaccu ucaaagugcu agaccucaag aacuacaucg acaaacaacu ccuaccaaua      600

cucaacaagc aaucuugcuc caucuccaac aucgaaaccg uaaucgaguu ccaacagaag      660

aacaaccgcc uccucgaaau cacccgcgag uucucuguca acgcaggggu caccacuccc      720

gucuccacau acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugcccaua      780

accaacgacc agaaaaagcu aaugagcaau aacguccaaa ucguuagaca acaaaguuau      840

uccaucaugu gcaucaucaa agaagaaguc cucgccuacg ucguacaacu cccccucuau      900

ggcgucaucg acacccccug cuggaaacug cacacaucac cccucugcac cacaaacacc      960

aaagaaggcu caaacaucug ccuaacucgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcagcguau cauucuuucc ccaagccgaa acaugcaaag uucaauccaa ccgcgucuuc     1080

ugcgacacaa ugaacuccag aacgcucccc agcgaaguca accucuguaa cguagacauc     1140

uucaacccua aguacgacug caaaaucaug accuccaaaa cugauguauc cuccuccguc     1200

aucacauccc ugggcgccau cgucagcugc uacggcaaaa caaaaugcac ugccucaaac     1260

aaaugccgag guaucauaaa gaccuucuca aacggaugcg auuacgucag caacaaaggc     1320

gucgacaccg ucagugucgg caacacccuc uacuacguca acaaacaaga aggaaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccagcgac     1440

gaguucgacg ccuccaucuc acaagucaac gaaaagauaa accaaucucu agccuucauc     1500

cgcaaauccg augaacuccu gcauaacguc aacgccggca aauccaccac aaacaucaug     1560

aucacuacca uaaucaucgu cauaaucgua auccuccuau cucuuaucgc agucggccua     1620

cuacucuacu gcaaagcccg cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  5976
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5976
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5977
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5977
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccucgagg gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug      540

gucucccuca gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug      780

cugucccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccggcaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu ggggcuccug cuguacugca aggcccggug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5978
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5978
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5979
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5979
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug      480

caccucgagg gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug      540

gucucucuca gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac      600

uacauugaua aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc      660

gagaccguga uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu      720

ucugucaaug cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug      780

uugagccuca ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau      840

guccagaucg uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua      900

gcauauguag ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau      960

acaagcccac ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg     1020

gaucgugggu gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc     1080

uguaagguuc agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc     1140

gaggucaauc ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc     1200

uccaaaacag acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac     1260

ggcaagacua aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau     1320

ggaugugauu augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac     1380

uauguuaaca agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuu ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag     1500

aaaaucaacc agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac     1560

gcgggcaagu caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu     1620

cugcuaaguc ucaucgccgu cggccugcuu uuguacugca aagcacgcug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5980
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5980
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5981
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5981
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc      480

caccuggagg gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc      540

gugucccuca gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac      600

uacauugaua aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc      660

gagaccguga uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu      720

uccgugaaug ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug      780

cucucucuga ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau      840

gugcagaucg ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug      900

gcuuaugugg uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau      960

acgucuccuc ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc     1020

gaucgcggcu gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg     1080

uguaaggugc agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu     1140

gaggugaauc ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc     1200

agcaaaacag acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac     1260

ggcaagacaa aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau     1320

ggaugugauu auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac     1380

uauguuaaca agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu     1440

uaugacccuc ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag     1500

aaaauuaacc agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac     1560

gccggcaaga gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu     1620

cugcuuucuc ugaucgccgu ggggcuccug cuguacugca aagcuagaug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5982
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5982
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uuuuaauacu gaaagcaaau gccaucacaa ccauacuaac ugccgucaca      180

uucugcuuug caucaggaca aaacauaaca gaagaauuuu accaauccac augcucagca      240

guaucaaaag gauaucuauc ggcacuuaga acuggauggu acacaagugu uauaacuaua      300

gaacucucaa acauaaaaga aaacaaaugc aauggaacag acgcaaaagu aaaacuaaua      360

aaacaagaac ucgauaaaua uaaaaaugca guaaccgaac uacaacuauu aaugcaaagc      420

acacccgcaa caggcagcgg aucagcaaua gcaagcggag ucgcaguaug uaaaguacua      480

caucuagaag gagaagucaa caaaaucaaa ucugcacuuc uauccacaaa caaagcugua      540

guaucccuau ccggaugcgg agucucagua uuaacuuuua aaguacuaga ccuuaaaaac      600

uacauagaua aacaacuauu accaauacua aauaaacaau caugcagcau auccaauaua      660

gagacaguaa uugaauuuca acaaaaaaac aacagauuac uagaaauuac ucgugaauuu      720

uccguaaaug ccggagucac aacaccagua ucaaccuaua ugcuaacaaa cagcgaacua      780

cuuagcuuaa uaaaugacau gccaauaaca aaugaccaaa aaaaacuuau gucaaauaac      840

guacaaaucg ucagacaaca auccuacucu auaaugugua uaauuaaaga agaaguccua      900

gcauacguag uucaauuacc acucuaugga guaauagaua caccaugcug gaaacuacac      960

acgucaccac uauguacaac aaacacaaaa gaaggaucca auauaugccu aacaagaacc     1020

gacagaggcu gguauuguga caacgcagga uccguuucau ucuucccaca agcagaaacc     1080

uguaaaguac aaucuaauag aguauuuugc gacacaauga acaguagaac acuaccaagc     1140

gagguuaauc uauguaacgu agacauauuc aauccaaaau augauugcaa aauaaugaca     1200

ucaaaaacag auguaucguc gaguguaaua acaagucugg gagcuauagu aagcugcuac     1260

ggcaagacga aauguaccgc uucaaauaaa ugcagaggaa ucauuaaaac auucucgaac     1320

ggaugcgacu acguaaguaa uaaagguguc gacaccguau caguagggaa uacauuauac     1380

uacgucaaca aacaagaagg aaaaucucua uauguaaaag gagaaccaau aauaaauuuc     1440

uaugacccuc uaguauuccc aucagaugaa uuugacgcuu ccauaucaca aguaaacgaa     1500

aaaaucaauc aaucuuuagc auucauacga aaaagugaug aacuccuaca caacgucaac     1560

gcaggaaaaa gcacaacaaa uauaaugauc acaacaauca ucauaguaau aauaguaaua     1620

cuacuaucau uaauagcagu aggauuauug cuuuacugca aagcacgaua gggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5983
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5983
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca caauacucac cgccguaacc      180

uucugcuuug cgucgggaca aaacaucacc gaagaguucu accaauccac uugcuccgca      240

guaagcaaag gauaccucuc cgcccugcga accgguuggu acacaucagu caucacaauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcaccg acgcaaaggu caaauuaauc      360

aagcaagaac uagacaaaua caaaaacgcc gucacagaac uccagcugcu aaugcagagc      420

acacccgcaa cuggcagcgg auccgccauc gcaucaggag ucgccgugug caaaguccua      480

caccucgaag gagaagugaa caaaaucaaa ucagcccuac ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg ugucuccguc cuaaccuuca aagugcuaga ccucaagaac      600

uacaucgaca aacaacuccu accaauacuc aacaagcaau cuugcuccau cuccaacauc      660

gaaaccguaa ucgaguucca acagaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

ucugucaacg caggggucac cacucccguc uccacauaca ugcucacaaa cuccgaacuc      780

cucagccuca ucaacgacau gcccauaacc aacgaccaga aaaagcuaau gagcaauaac      840

guccaaaucg uuagacaaca aaguuauucc aucaugugca ucaucaaaga agaaguccuc      900

gccuacgucg uacaacuccc ccucuauggc gucaucgaca cccccugcug gaaacugcac      960

acaucacccc ucugcaccac aaacaccaaa gaaggcucaa acaucugccu aacucgcacc     1020

gaccgcggcu gguacugcga caacgccggc agcguaucau ucuuucccca agccgaaaca     1080

ugcaaaguuc aauccaaccg cgucuucugc gacacaauga acuccagaac gcuccccagc     1140

gaagucaacc ucuguaacgu agacaucuuc aacccuaagu acgacugcaa aaucaugacc     1200

uccaaaacug auguauccuc cuccgucauc acaucccugg gcgccaucgu cagcugcuac     1260

ggcaaaacaa aaugcacugc cucaaacaaa ugccgaggua ucauaaagac cuucucaaac     1320

ggaugcgauu acgucagcaa caaaggcguc gacaccguca gugucggcaa cacccucuac     1380

uacgucaaca aacaagaagg aaaaucccuc uacgucaaag gcgaacccau caucaacuuc     1440

uacgaccccc ucgucuuccc cagcgacgag uucgacgccu ccaucucaca agucaacgaa     1500

aagauaaacc aaucucuagc cuucauccgc aaauccgaug aacuccugca uaacgucaac     1560

gccggcaaau ccaccacaaa caucaugauc acuaccauaa ucaucgucau aaucguaauc     1620

cuccuaucuc uuaucgcagu cggccuacua cucuacugca aagcccgcua aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  5984
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5984
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5985
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5985
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccggugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5986
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5986
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5987
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5987
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5988
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5988
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5989
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5989
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagaugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5990
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5990
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacugaaa      120

gcaaaugcca ucacaaccau acuaacugcc gucacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca auccacaugc ucagcaguau caaaaggaua ucuaucggca      240

cuuagaacug gaugguacac aaguguuaua acuauagaac ucucaaacau aaaagaaaac      300

aaaugcaaug gaacagacgc aaaaguaaaa cuaauaaaac aagaacucga uaaauauaaa      360

aaugcaguaa ccgaacuaca acuauuaaug caaagcacac ccgcaacagg cagcggauca      420

gcaauagcaa gcggagucgc aguauguaaa guacuacauc uagaaggaga agucaacaaa      480

aucaaaucug cacuucuauc cacaaacaaa gcuguaguau cccuauccgg augcggaguc      540

ucaguauuaa cuuuuaaagu acuagaccuu aaaaacuaca uagauaaaca acuauuacca      600

auacuaaaua aacaaucaug cagcauaucc aauauagaga caguaauuga auuucaacaa      660

aaaaacaaca gauuacuaga aauuacucgu gaauuuuccg uaaaugccgg agucacaaca      720

ccaguaucaa ccuauaugcu aacaaacagc gaacuacuua gcuuaauaaa ugacaugcca      780

auaacaaaug accaaaaaaa acuuauguca aauaacguac aaaucgucag acaacaaucc      840

uacucuauaa uguguauaau uaaagaagaa guccuagcau acguaguuca auuaccacuc      900

uauggaguaa uagauacacc augcuggaaa cuacacacgu caccacuaug uacaacaaac      960

acaaaagaag gauccaauau augccuaaca agaaccgaca gaggcuggua uugugacaac     1020

gcaggauccg uuucauucuu cccacaagca gaaaccugua aaguacaauc uaauagagua     1080

uuuugcgaca caaugaacag uagaacacua ccaagcgagg uuaaucuaug uaacguagac     1140

auauucaauc caaaauauga uugcaaaaua augacaucaa aaacagaugu aucgucgagu     1200

guaauaacaa gucugggagc uauaguaagc ugcuacggca agacgaaaug uaccgcuuca     1260

aauaaaugca gaggaaucau uaaaacauuc ucgaacggau gcgacuacgu aaguaauaaa     1320

ggugucgaca ccguaucagu agggaauaca uuauacuacg ucaacaaaca agaaggaaaa     1380

ucucuauaug uaaaaggaga accaauaaua aauuucuaug acccucuagu auucccauca     1440

gaugaauuug acgcuuccau aucacaagua aacgaaaaaa ucaaucaauc uuuagcauuc     1500

auacgaaaaa gugaugaacu ccuacacaac gucaacgcag gaaaaagcac aacaaauaua     1560

augaucacaa caaucaucau aguaauaaua guaauacuac uaucauuaau agcaguagga     1620

uuauugcuuu acugcaaagc acgauaggga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5991
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5991
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacaau acucaccgcc guaaccuucu gcuuugcguc gggacaaaac      180

aucaccgaag aguucuacca auccacuugc uccgcaguaa gcaaaggaua ccucuccgcc      240

cugcgaaccg guugguacac aucagucauc acaaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaggucaaa uuaaucaagc aagaacuaga caaauacaaa      360

aacgccguca cagaacucca gcugcuaaug cagagcacac ccgcaacugg cagcggaucc      420

gccaucgcau caggagucgc cgugugcaaa guccuacacc ucgaaggaga agugaacaaa      480

aucaaaucag cccuacucuc caccaacaag gccgucgucu cccucuccgg cugcgguguc      540

uccguccuaa ccuucaaagu gcuagaccuc aagaacuaca ucgacaaaca acuccuacca      600

auacucaaca agcaaucuug cuccaucucc aacaucgaaa ccguaaucga guuccaacag      660

aagaacaacc gccuccucga aaucacccgc gaguucucug ucaacgcagg ggucaccacu      720

cccgucucca cauacaugcu cacaaacucc gaacuccuca gccucaucaa cgacaugccc      780

auaaccaacg accagaaaaa gcuaaugagc aauaacgucc aaaucguuag acaacaaagu      840

uauuccauca ugugcaucau caaagaagaa guccucgccu acgucguaca acucccccuc      900

uauggcguca ucgacacccc cugcuggaaa cugcacacau caccccucug caccacaaac      960

accaaagaag gcucaaacau cugccuaacu cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcagcg uaucauucuu uccccaagcc gaaacaugca aaguucaauc caaccgcguc     1080

uucugcgaca caaugaacuc cagaacgcuc cccagcgaag ucaaccucug uaacguagac     1140

aucuucaacc cuaaguacga cugcaaaauc augaccucca aaacugaugu auccuccucc     1200

gucaucacau cccugggcgc caucgucagc ugcuacggca aaacaaaaug cacugccuca     1260

aacaaaugcc gagguaucau aaagaccuuc ucaaacggau gcgauuacgu cagcaacaaa     1320

ggcgucgaca ccgucagugu cggcaacacc cucuacuacg ucaacaaaca agaaggaaaa     1380

ucccucuacg ucaaaggcga acccaucauc aacuucuacg acccccucgu cuuccccagc     1440

gacgaguucg acgccuccau cucacaaguc aacgaaaaga uaaaccaauc ucuagccuuc     1500

auccgcaaau ccgaugaacu ccugcauaac gucaacgccg gcaaauccac cacaaacauc     1560

augaucacua ccauaaucau cgucauaauc guaauccucc uaucucuuau cgcagucggc     1620

cuacuacucu acugcaaagc ccgcuaagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  5992
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5992
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  5993
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  5993
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccggugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  5994
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  5994
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  5995
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  5995
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  5996
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  5996
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  5997
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  5997
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagaugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  5998
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  5998
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacugaaa      120

gcaaaugcca ucacaaccau acuaacugcc gucacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca auccacaugc ucagcaguau caaaaggaua ucuaucggca      240

cuuagaacug gaugguacac aaguguuaua acuauagaac ucucaaacau aaaagaaaac      300

aaaugcaaug gaacagacgc aaaaguaaaa cuaauaaaac aagaacucga uaaauauaaa      360

aaugcaguaa ccgaacuaca acuauuaaug caaagcacac ccgcaacagg cagcggauca      420

gcaauagcaa gcggagucgc aguauguaaa guacuacauc uagaaggaga agucaacaaa      480

aucaaaucug cacuucuauc cacaaacaaa gcuguaguau cccuauccgg augcggaguc      540

ucaguauuaa cuuuuaaagu acuagaccuu aaaaacuaca uagauaaaca acuauuacca      600

auacuaaaua aacaaucaug cagcauaucc aauauagaga caguaauuga auuucaacaa      660

aaaaacaaca gauuacuaga aauuacucgu gaauuuuccg uaaaugccgg agucacaaca      720

ccaguaucaa ccuauaugcu aacaaacagc gaacuacuua gcuuaauaaa ugacaugcca      780

auaacaaaug accaaaaaaa acuuauguca aauaacguac aaaucgucag acaacaaucc      840

uacucuauaa uguguauaau uaaagaagaa guccuagcau acguaguuca auuaccacuc      900

uauggaguaa uagauacacc augcuggaaa cuacacacgu caccacuaug uacaacaaac      960

acaaaagaag gauccaauau augccuaaca agaaccgaca gaggcuggua uugugacaac     1020

gcaggauccg uuucauucuu cccacaagca gaaaccugua aaguacaauc uaauagagua     1080

uuuugcgaca caaugaacag uagaacacua ccaagcgagg uuaaucuaug uaacguagac     1140

auauucaauc caaaauauga uugcaaaaua augacaucaa aaacagaugu aucgucgagu     1200

guaauaacaa gucugggagc uauaguaagc ugcuacggca agacgaaaug uaccgcuuca     1260

aauaaaugca gaggaaucau uaaaacauuc ucgaacggau gcgacuacgu aaguaauaaa     1320

ggugucgaca ccguaucagu agggaauaca uuauacuacg ucaacaaaca agaaggaaaa     1380

ucucuauaug uaaaaggaga accaauaaua aauuucuaug acccucuagu auucccauca     1440

gaugaauuug acgcuuccau aucacaagua aacgaaaaaa ucaaucaauc uuuagcauuc     1500

auacgaaaaa gugaugaacu ccuacacaac gucaacgcag gaaaaagcac aacaaauaua     1560

augaucacaa caaucaucau aguaauaaua guaauacuac uaucauuaau agcaguagga     1620

uuauugcuuu acugcaaagc acgauaggga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  5999
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  5999
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacaau acucaccgcc guaaccuucu gcuuugcguc gggacaaaac      180

aucaccgaag aguucuacca auccacuugc uccgcaguaa gcaaaggaua ccucuccgcc      240

cugcgaaccg guugguacac aucagucauc acaaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaggucaaa uuaaucaagc aagaacuaga caaauacaaa      360

aacgccguca cagaacucca gcugcuaaug cagagcacac ccgcaacugg cagcggaucc      420

gccaucgcau caggagucgc cgugugcaaa guccuacacc ucgaaggaga agugaacaaa      480

aucaaaucag cccuacucuc caccaacaag gccgucgucu cccucuccgg cugcgguguc      540

uccguccuaa ccuucaaagu gcuagaccuc aagaacuaca ucgacaaaca acuccuacca      600

auacucaaca agcaaucuug cuccaucucc aacaucgaaa ccguaaucga guuccaacag      660

aagaacaacc gccuccucga aaucacccgc gaguucucug ucaacgcagg ggucaccacu      720

cccgucucca cauacaugcu cacaaacucc gaacuccuca gccucaucaa cgacaugccc      780

auaaccaacg accagaaaaa gcuaaugagc aauaacgucc aaaucguuag acaacaaagu      840

uauuccauca ugugcaucau caaagaagaa guccucgccu acgucguaca acucccccuc      900

uauggcguca ucgacacccc cugcuggaaa cugcacacau caccccucug caccacaaac      960

accaaagaag gcucaaacau cugccuaacu cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcagcg uaucauucuu uccccaagcc gaaacaugca aaguucaauc caaccgcguc     1080

uucugcgaca caaugaacuc cagaacgcuc cccagcgaag ucaaccucug uaacguagac     1140

aucuucaacc cuaaguacga cugcaaaauc augaccucca aaacugaugu auccuccucc     1200

gucaucacau cccugggcgc caucgucagc ugcuacggca aaacaaaaug cacugccuca     1260

aacaaaugcc gagguaucau aaagaccuuc ucaaacggau gcgauuacgu cagcaacaaa     1320

ggcgucgaca ccgucagugu cggcaacacc cucuacuacg ucaacaaaca agaaggaaaa     1380

ucccucuacg ucaaaggcga acccaucauc aacuucuacg acccccucgu cuuccccagc     1440

gacgaguucg acgccuccau cucacaaguc aacgaaaaga uaaaccaauc ucuagccuuc     1500

auccgcaaau ccgaugaacu ccugcauaac gucaacgccg gcaaauccac cacaaacauc     1560

augaucacua ccauaaucau cgucauaauc guaauccucc uaucucuuau cgcagucggc     1620

cuacuacucu acugcaaagc ccgcuaagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  6000
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6000
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6001
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6001
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccggugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6002
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6002
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6003
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6003
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6004
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6004
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6005
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6005
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagaugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6006
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6006
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacugaaa      120

gcaaaugcca ucacaaccau acuaacugcc gucacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca auccacaugc ucagcaguau caaaaggaua ucuaucggca      240

cuuagaacug gaugguacac aaguguuaua acuauagaac ucucaaacau aaaagaaaac      300

aaaugcaaug gaacagacgc aaaaguaaaa cuaauaaaac aagaacucga uaaauauaaa      360

aaugcaguaa ccgaacuaca acuauuaaug caaagcacac ccgcaacagg cagcggauca      420

gcaauagcaa gcggagucgc aguauguaaa guacuacauc uagaaggaga agucaacaaa      480

aucaaaucug cacuucuauc cacaaacaaa gcuguaguau cccuauccgg augcggaguc      540

ucaguauuaa cuuuuaaagu acuagaccuu aaaaacuaca uagauaaaca acuauuacca      600

auacuaaaua aacaaucaug cagcauaucc aauauagaga caguaauuga auuucaacaa      660

aaaaacaaca gauuacuaga aauuacucgu gaauuuuccg uaaaugccgg agucacaaca      720

ccaguaucaa ccuauaugcu aacaaacagc gaacuacuua gcuuaauaaa ugacaugcca      780

auaacaaaug accaaaaaaa acuuauguca aauaacguac aaaucgucag acaacaaucc      840

uacucuauaa uguguauaau uaaagaagaa guccuagcau acguaguuca auuaccacuc      900

uauggaguaa uagauacacc augcuggaaa cuacacacgu caccacuaug uacaacaaac      960

acaaaagaag gauccaauau augccuaaca agaaccgaca gaggcuggua uugugacaac     1020

gcaggauccg uuucauucuu cccacaagca gaaaccugua aaguacaauc uaauagagua     1080

uuuugcgaca caaugaacag uagaacacua ccaagcgagg uuaaucuaug uaacguagac     1140

auauucaauc caaaauauga uugcaaaaua augacaucaa aaacagaugu aucgucgagu     1200

guaauaacaa gucugggagc uauaguaagc ugcuacggca agacgaaaug uaccgcuuca     1260

aauaaaugca gaggaaucau uaaaacauuc ucgaacggau gcgacuacgu aaguaauaaa     1320

ggugucgaca ccguaucagu agggaauaca uuauacuacg ucaacaaaca agaaggaaaa     1380

ucucuauaug uaaaaggaga accaauaaua aauuucuaug acccucuagu auucccauca     1440

gaugaauuug acgcuuccau aucacaagua aacgaaaaaa ucaaucaauc uuuagcauuc     1500

auacgaaaaa gugaugaacu ccuacacaac gucaacgcag gaaaaagcac aacaaauaua     1560

augaucacaa caaucaucau aguaauaaua guaauacuac uaucauuaau agcaguagga     1620

uuauugcuuu acugcaaagc acgauaggga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6007
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6007
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacaau acucaccgcc guaaccuucu gcuuugcguc gggacaaaac      180

aucaccgaag aguucuacca auccacuugc uccgcaguaa gcaaaggaua ccucuccgcc      240

cugcgaaccg guugguacac aucagucauc acaaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaggucaaa uuaaucaagc aagaacuaga caaauacaaa      360

aacgccguca cagaacucca gcugcuaaug cagagcacac ccgcaacugg cagcggaucc      420

gccaucgcau caggagucgc cgugugcaaa guccuacacc ucgaaggaga agugaacaaa      480

aucaaaucag cccuacucuc caccaacaag gccgucgucu cccucuccgg cugcgguguc      540

uccguccuaa ccuucaaagu gcuagaccuc aagaacuaca ucgacaaaca acuccuacca      600

auacucaaca agcaaucuug cuccaucucc aacaucgaaa ccguaaucga guuccaacag      660

aagaacaacc gccuccucga aaucacccgc gaguucucug ucaacgcagg ggucaccacu      720

cccgucucca cauacaugcu cacaaacucc gaacuccuca gccucaucaa cgacaugccc      780

auaaccaacg accagaaaaa gcuaaugagc aauaacgucc aaaucguuag acaacaaagu      840

uauuccauca ugugcaucau caaagaagaa guccucgccu acgucguaca acucccccuc      900

uauggcguca ucgacacccc cugcuggaaa cugcacacau caccccucug caccacaaac      960

accaaagaag gcucaaacau cugccuaacu cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcagcg uaucauucuu uccccaagcc gaaacaugca aaguucaauc caaccgcguc     1080

uucugcgaca caaugaacuc cagaacgcuc cccagcgaag ucaaccucug uaacguagac     1140

aucuucaacc cuaaguacga cugcaaaauc augaccucca aaacugaugu auccuccucc     1200

gucaucacau cccugggcgc caucgucagc ugcuacggca aaacaaaaug cacugccuca     1260

aacaaaugcc gagguaucau aaagaccuuc ucaaacggau gcgauuacgu cagcaacaaa     1320

ggcgucgaca ccgucagugu cggcaacacc cucuacuacg ucaacaaaca agaaggaaaa     1380

ucccucuacg ucaaaggcga acccaucauc aacuucuacg acccccucgu cuuccccagc     1440

gacgaguucg acgccuccau cucacaaguc aacgaaaaga uaaaccaauc ucuagccuuc     1500

auccgcaaau ccgaugaacu ccugcauaac gucaacgccg gcaaauccac cacaaacauc     1560

augaucacua ccauaaucau cgucauaauc guaauccucc uaucucuuau cgcagucggc     1620

cuacuacucu acugcaaagc ccgcuaagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  6008
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6008
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucagc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccggacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6009
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6009
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gcuccugaug caguccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc ucgagggcga ggugaacaag      480

aucaaguccg cccugcugag caccaacaag gccguggucu cccucagcgg gugcggcgug      540

uccgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcagagcug cuccaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg ggucaccacg      720

cccgugagca ccuacaugcu caccaacagc gagcugcugu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccccug      900

uacggcguga ucgacacgcc gugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gguccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggcuccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccggacccuc cccuccgagg ucaaccugug caacguggac     1140

aucuucaacc cgaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggggc caucgugucc ugcuacggca agaccaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcgucgaca cggugagcgu ggggaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccuguacg ugaaggggga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg gcaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggg     1620

cuccugcugu acugcaaggc ccggugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6010
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6010
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucucc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccgcacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggcaag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6011
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6011
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gcuucugaug cagucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucuguaag guguugcacc ucgagggcga aguuaacaaa      480

aucaagagug cucugcuguc cacgaauaaa gccguggucu cucucagcgg uugcggggug      540

uccguauuaa cuuuuaaggu ucuggaccuu aagaacuaca uugauaaaca auugcugccu      600

auccuaaaua agcagucaug uaguauuagc aacaucgaga ccgugauaga guuccagcag      660

aaaaauaaca ggcuccugga aauuacacgg gaguuuucug ucaaugcggg agugacuacc      720

ccagugucca cauauaugcu uaccaacuca gaacuguuga gccucaucaa ugacaugccg      780

auuacgaacg aucaaaagaa acugaugagu aacaaugucc agaucguucg ccagcagucu      840

uacuccauca ugugcauuau aaaggaggaa guguuagcau auguagugca acugccccuc      900

uacggcguca ucgacacucc uuguuggaaa cuucauacaa gcccacugug caccacuaac      960

acaaaggagg gcucgaauau uuguuugacc cgaacggauc guggguggua cugcgacaac     1020

gccggaucug uguccuucuu uccccaggcu gaaaccugua agguucaguc aaauagagug     1080

uucugcgaua caaugaacag uagaacucug ccuagcgagg ucaaucucug caacguggac     1140

aucuuuaauc caaaauauga uuguaagaua augaccucca aaacagacgu aucuagcuca     1200

guuauuacca gucugggugc caucgugucc ugcuacggca agacuaaaug uacagcaagc     1260

aacaagugca gggggaucau uaagaccuuc ucuaauggau gugauuaugu cucaaacaaa     1320

ggcguggaca cugucagugu ggguaauacg cuuuacuaug uuaacaagca agaggggaaa     1380

agccuguacg ugaagggaga acccaucauu aauuuuuaug acccuuuggu auucccaucc     1440

gaugaguuug acgcuucuau aucgcagguc aacgagaaaa ucaaccagag ccucgccuuc     1500

auucggaagu ccgaugaacu guuacacaau gugaacgcgg gcaagucaac aaccaauauc     1560

augaucacua ccauuauaau cguuauuauc gugauucugc uaagucucau cgccgucggc     1620

cugcuuuugu acugcaaagc acgcugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6012
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6012
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucagc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag cagaacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggcaag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6013
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6013
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gcugcugaug caguccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc gguguguaag guucuccacc uggaggggga agugaacaaa      480

aucaagagcg cccuucuguc uaccaauaaa gcugucgugu cccucagcgg augcggcguu      540

ucugugcuga cauuuaaggu ccuugaccug aagaacuaca uugauaaaca acuccugccu      600

auccugaaua agcaguccug uagcauuucu aacaucgaga ccgugauuga guuccagcag      660

aaaaauaacc ggcuccugga aaucacgcgc gaguuuuccg ugaaugccgg cgucacaacc      720

ccgguuagca cauauaugcu uaccaacucc gaacugcucu cucugaucaa ugacaugccc      780

auuaccaacg aucaaaagaa acuuaugagc aacaaugugc agaucgugag acagcagucc      840

uacagcauua ugugcaucau uaaggaggaa guccuggcuu augugguuca acucccucug      900

uacgggguga ucgacacacc cuguuggaaa cugcauacgu cuccucucug caccacaaac      960

accaaggagg gauccaauau cugucugaca cggaccgauc gcggcuggua cugcgacaac     1020

gccgggagcg ucucuuucuu uccccaggcg gaaacgugua aggugcagag caauagaguu     1080

uucugcgaua caaugaacuc cagaacccug ccuucugagg ugaaucucug caacgucgac     1140

auuuuuaauc cgaaauauga uuguaagauc augaccagca aaacagacgu guccagcucu     1200

gucauuaccu cccugggagc caucgugagc ugcuacggca agacaaaaug uacggcuucu     1260

aacaagugcc gggggauuau caagaccuuc uccaauggau gugauuaugu uagcaacaaa     1320

ggcguggaca cagucuccgu gggcaauacc cuuuacuaug uuaacaagca agaggggaaa     1380

ucucuguacg ugaagggaga acccaucauu aauuuuuaug acccucucgu cuuccccagc     1440

gaugaguuug acgccuccau cucucaggug aacgagaaaa uuaaccagag ccuggcuuuc     1500

auccgcaagu ccgaugaacu gcuccacaau gugaacgccg gcaagagcac aaccaauauu     1560

augaucacga ccauuaucau cguuauuauc gucauucugc uuucucugau cgccgugggg     1620

cuccugcugu acugcaaagc uagaugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6014
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6014
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuuuu aauacugaaa      120

gcaaaugcca ucacaaccau acuaacugcc gucacauucu gcuuugcauc aggacaaaac      180

auaacagaag aauuuuacca auccacaugc ucagcaguau caaaaggaua ucuaucggca      240

cuuagaacug gaugguacac aaguguuaua acuauagaac ucucaaacau aaaagaaaac      300

aaaugcaaug gaacagacgc aaaaguaaaa cuaauaaaac aagaacucga uaaauauaaa      360

aaugcaguaa ccgaacuaca acuauuaaug caaagcacac ccgcaacagg cagcggauca      420

gcaauagcaa gcggagucgc aguauguaaa guacuacauc uagaaggaga agucaacaaa      480

aucaaaucug cacuucuauc cacaaacaaa gcuguaguau cccuauccgg augcggaguc      540

ucaguauuaa cuuuuaaagu acuagaccuu aaaaacuaca uagauaaaca acuauuacca      600

auacuaaaua aacaaucaug cagcauaucc aauauagaga caguaauuga auuucaacaa      660

aaaaacaaca gauuacuaga aauuacucgu gaauuuuccg uaaaugccgg agucacaaca      720

ccaguaucaa ccuauaugcu aacaaacagc gaacuacuua gcuuaauaaa ugacaugcca      780

auaacaaaug accaaaaaaa acuuauguca aauaacguac aaaucgucag acaacaaucc      840

uacucuauaa uguguauaau uaaagaagaa guccuagcau acguaguuca auuaccacuc      900

uauggaguaa uagauacacc augcuggaaa cuacacacgu caccacuaug uacaacaaac      960

acaaaagaag gauccaauau augccuaaca agaaccgaca gaggcuggua uugugacaac     1020

gcaggauccg uuucauucuu cccacaagca gaaaccugua aaguacaauc uaauagagua     1080

uuuugcgaca caaugaacag uagaacacua ccaagcgagg uuaaucuaug uaacguagac     1140

auauucaauc caaaauauga uugcaaaaua augacaucaa aaacagaugu aucgucgagu     1200

guaauaacaa gucugggagc uauaguaagc ugcuacggca agacgaaaug uaccgcuuca     1260

aauaaaugca gaggaaucau uaaaacauuc ucgaacggau gcgacuacgu aaguaauaaa     1320

ggugucgaca ccguaucagu agggaauaca uuauacuacg ucaacaaaca agaaggaaaa     1380

ucucuauaug uaaaaggaga accaauaaua aauuucuaug acccucuagu auucccauca     1440

gaugaauuug acgcuuccau aucacaagua aacgaaaaaa ucaaucaauc uuuagcauuc     1500

auacgaaaaa gugaugaacu ccuacacaac gucaacgcag gaaaaagcac aacaaauaua     1560

augaucacaa caaucaucau aguaauaaua guaauacuac uaucauuaau agcaguagga     1620

uuauugcuuu acugcaaagc acgauaggga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6015
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6015
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacaau acucaccgcc guaaccuucu gcuuugcguc gggacaaaac      180

aucaccgaag aguucuacca auccacuugc uccgcaguaa gcaaaggaua ccucuccgcc      240

cugcgaaccg guugguacac aucagucauc acaaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc aaaggucaaa uuaaucaagc aagaacuaga caaauacaaa      360

aacgccguca cagaacucca gcugcuaaug cagagcacac ccgcaacugg cagcggaucc      420

gccaucgcau caggagucgc cgugugcaaa guccuacacc ucgaaggaga agugaacaaa      480

aucaaaucag cccuacucuc caccaacaag gccgucgucu cccucuccgg cugcgguguc      540

uccguccuaa ccuucaaagu gcuagaccuc aagaacuaca ucgacaaaca acuccuacca      600

auacucaaca agcaaucuug cuccaucucc aacaucgaaa ccguaaucga guuccaacag      660

aagaacaacc gccuccucga aaucacccgc gaguucucug ucaacgcagg ggucaccacu      720

cccgucucca cauacaugcu cacaaacucc gaacuccuca gccucaucaa cgacaugccc      780

auaaccaacg accagaaaaa gcuaaugagc aauaacgucc aaaucguuag acaacaaagu      840

uauuccauca ugugcaucau caaagaagaa guccucgccu acgucguaca acucccccuc      900

uauggcguca ucgacacccc cugcuggaaa cugcacacau caccccucug caccacaaac      960

accaaagaag gcucaaacau cugccuaacu cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcagcg uaucauucuu uccccaagcc gaaacaugca aaguucaauc caaccgcguc     1080

uucugcgaca caaugaacuc cagaacgcuc cccagcgaag ucaaccucug uaacguagac     1140

aucuucaacc cuaaguacga cugcaaaauc augaccucca aaacugaugu auccuccucc     1200

gucaucacau cccugggcgc caucgucagc ugcuacggca aaacaaaaug cacugccuca     1260

aacaaaugcc gagguaucau aaagaccuuc ucaaacggau gcgauuacgu cagcaacaaa     1320

ggcgucgaca ccgucagugu cggcaacacc cucuacuacg ucaacaaaca agaaggaaaa     1380

ucccucuacg ucaaaggcga acccaucauc aacuucuacg acccccucgu cuuccccagc     1440

gacgaguucg acgccuccau cucacaaguc aacgaaaaga uaaaccaauc ucuagccuuc     1500

auccgcaaau ccgaugaacu ccugcauaac gucaacgccg gcaaauccac cacaaacauc     1560

augaucacua ccauaaucau cgucauaauc guaauccucc uaucucuuau cgcagucggc     1620

cuacuacucu acugcaaagc ccgcuaagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  6016
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6016
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6017
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6017
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6018
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6018
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6019
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6019
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6020
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6020
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6021
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6021
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6022
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6022
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac ugaaagcaaa ugccaucaca accauacuaa cugccgucac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucca caugcucagc aguaucaaaa      300

ggauaucuau cggcacuuag aacuggaugg uacacaagug uuauaacuau agaacucuca      360

aacauaaaag aaaacaaaug caauggaaca gacgcaaaag uaaaacuaau aaaacaagaa      420

cucgauaaau auaaaaaugc aguaaccgaa cuacaacuau uaaugcaaag cacacccgca      480

acaggcagcg gaucagcaau agcaagcgga gucgcaguau guaaaguacu acaucuagaa      540

ggagaaguca acaaaaucaa aucugcacuu cuauccacaa acaaagcugu aguaucccua      600

uccggaugcg gagucucagu auuaacuuuu aaaguacuag accuuaaaaa cuacauagau      660

aaacaacuau uaccaauacu aaauaaacaa ucaugcagca uauccaauau agagacagua      720

auugaauuuc aacaaaaaaa caacagauua cuagaaauua cucgugaauu uuccguaaau      780

gccggaguca caacaccagu aucaaccuau augcuaacaa acagcgaacu acuuagcuua      840

auaaaugaca ugccaauaac aaaugaccaa aaaaaacuua ugucaaauaa cguacaaauc      900

gucagacaac aauccuacuc uauaaugugu auaauuaaag aagaaguccu agcauacgua      960

guucaauuac cacucuaugg aguaauagau acaccaugcu ggaaacuaca cacgucacca     1020

cuauguacaa caaacacaaa agaaggaucc aauauaugcc uaacaagaac cgacagaggc     1080

ugguauugug acaacgcagg auccguuuca uucuucccac aagcagaaac cuguaaagua     1140

caaucuaaua gaguauuuug cgacacaaug aacaguagaa cacuaccaag cgagguuaau     1200

cuauguaacg uagacauauu caauccaaaa uaugauugca aaauaaugac aucaaaaaca     1260

gauguaucgu cgaguguaau aacaagucug ggagcuauag uaagcugcua cggcaagacg     1320

aaauguaccg cuucaaauaa augcagagga aucauuaaaa cauucucgaa cggaugcgac     1380

uacguaagua auaaaggugu cgacaccgua ucaguaggga auacauuaua cuacgucaac     1440

aaacaagaag gaaaaucucu auauguaaaa ggagaaccaa uaauaaauuu cuaugacccu     1500

cuaguauucc caucagauga auuugacgcu uccauaucac aaguaaacga aaaaaucaau     1560

caaucuuuag cauucauacg aaaaagugau gaacuccuac acaacgucaa cgcaggaaaa     1620

agcacaacaa auauaaugau cacaacaauc aucauaguaa uaauaguaau acuacuauca     1680

uuaauagcag uaggauuauu gcuuuacugc aaagcacgau agggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6023
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6023
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acaauacuca ccgccguaac cuucugcuuu      240

gcgucgggac aaaacaucac cgaagaguuc uaccaaucca cuugcuccgc aguaagcaaa      300

ggauaccucu ccgcccugcg aaccgguugg uacacaucag ucaucacaau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcacc gacgcaaagg ucaaauuaau caagcaagaa      420

cuagacaaau acaaaaacgc cgucacagaa cuccagcugc uaaugcagag cacacccgca      480

acuggcagcg gauccgccau cgcaucagga gucgccgugu gcaaaguccu acaccucgaa      540

ggagaaguga acaaaaucaa aucagcccua cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gugucuccgu ccuaaccuuc aaagugcuag accucaagaa cuacaucgac      660

aaacaacucc uaccaauacu caacaagcaa ucuugcucca ucuccaacau cgaaaccgua      720

aucgaguucc aacagaagaa caaccgccuc cucgaaauca cccgcgaguu cucugucaac      780

gcagggguca ccacucccgu cuccacauac augcucacaa acuccgaacu ccucagccuc      840

aucaacgaca ugcccauaac caacgaccag aaaaagcuaa ugagcaauaa cguccaaauc      900

guuagacaac aaaguuauuc caucaugugc aucaucaaag aagaaguccu cgccuacguc      960

guacaacucc cccucuaugg cgucaucgac acccccugcu ggaaacugca cacaucaccc     1020

cucugcacca caaacaccaa agaaggcuca aacaucugcc uaacucgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cagcguauca uucuuucccc aagccgaaac augcaaaguu     1140

caauccaacc gcgucuucug cgacacaaug aacuccagaa cgcuccccag cgaagucaac     1200

cucuguaacg uagacaucuu caacccuaag uacgacugca aaaucaugac cuccaaaacu     1260

gauguauccu ccuccgucau cacaucccug ggcgccaucg ucagcugcua cggcaaaaca     1320

aaaugcacug ccucaaacaa augccgaggu aucauaaaga ccuucucaaa cggaugcgau     1380

uacgucagca acaaaggcgu cgacaccguc agugucggca acacccucua cuacgucaac     1440

aaacaagaag gaaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccagcgacga guucgacgcc uccaucucac aagucaacga aaagauaaac     1560

caaucucuag ccuucauccg caaauccgau gaacuccugc auaacgucaa cgccggcaaa     1620

uccaccacaa acaucaugau cacuaccaua aucaucguca uaaucguaau ccuccuaucu     1680

cuuaucgcag ucggccuacu acucuacugc aaagcccgcu aaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  6024
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6024
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6025
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6025
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6026
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6026
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6027
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6027
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6028
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6028
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6029
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6029
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6030
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6030
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac ugaaagcaaa ugccaucaca accauacuaa cugccgucac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucca caugcucagc aguaucaaaa      300

ggauaucuau cggcacuuag aacuggaugg uacacaagug uuauaacuau agaacucuca      360

aacauaaaag aaaacaaaug caauggaaca gacgcaaaag uaaaacuaau aaaacaagaa      420

cucgauaaau auaaaaaugc aguaaccgaa cuacaacuau uaaugcaaag cacacccgca      480

acaggcagcg gaucagcaau agcaagcgga gucgcaguau guaaaguacu acaucuagaa      540

ggagaaguca acaaaaucaa aucugcacuu cuauccacaa acaaagcugu aguaucccua      600

uccggaugcg gagucucagu auuaacuuuu aaaguacuag accuuaaaaa cuacauagau      660

aaacaacuau uaccaauacu aaauaaacaa ucaugcagca uauccaauau agagacagua      720

auugaauuuc aacaaaaaaa caacagauua cuagaaauua cucgugaauu uuccguaaau      780

gccggaguca caacaccagu aucaaccuau augcuaacaa acagcgaacu acuuagcuua      840

auaaaugaca ugccaauaac aaaugaccaa aaaaaacuua ugucaaauaa cguacaaauc      900

gucagacaac aauccuacuc uauaaugugu auaauuaaag aagaaguccu agcauacgua      960

guucaauuac cacucuaugg aguaauagau acaccaugcu ggaaacuaca cacgucacca     1020

cuauguacaa caaacacaaa agaaggaucc aauauaugcc uaacaagaac cgacagaggc     1080

ugguauugug acaacgcagg auccguuuca uucuucccac aagcagaaac cuguaaagua     1140

caaucuaaua gaguauuuug cgacacaaug aacaguagaa cacuaccaag cgagguuaau     1200

cuauguaacg uagacauauu caauccaaaa uaugauugca aaauaaugac aucaaaaaca     1260

gauguaucgu cgaguguaau aacaagucug ggagcuauag uaagcugcua cggcaagacg     1320

aaauguaccg cuucaaauaa augcagagga aucauuaaaa cauucucgaa cggaugcgac     1380

uacguaagua auaaaggugu cgacaccgua ucaguaggga auacauuaua cuacgucaac     1440

aaacaagaag gaaaaucucu auauguaaaa ggagaaccaa uaauaaauuu cuaugacccu     1500

cuaguauucc caucagauga auuugacgcu uccauaucac aaguaaacga aaaaaucaau     1560

caaucuuuag cauucauacg aaaaagugau gaacuccuac acaacgucaa cgcaggaaaa     1620

agcacaacaa auauaaugau cacaacaauc aucauaguaa uaauaguaau acuacuauca     1680

uuaauagcag uaggauuauu gcuuuacugc aaagcacgau agggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6031
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6031
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acaauacuca ccgccguaac cuucugcuuu      240

gcgucgggac aaaacaucac cgaagaguuc uaccaaucca cuugcuccgc aguaagcaaa      300

ggauaccucu ccgcccugcg aaccgguugg uacacaucag ucaucacaau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcacc gacgcaaagg ucaaauuaau caagcaagaa      420

cuagacaaau acaaaaacgc cgucacagaa cuccagcugc uaaugcagag cacacccgca      480

acuggcagcg gauccgccau cgcaucagga gucgccgugu gcaaaguccu acaccucgaa      540

ggagaaguga acaaaaucaa aucagcccua cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gugucuccgu ccuaaccuuc aaagugcuag accucaagaa cuacaucgac      660

aaacaacucc uaccaauacu caacaagcaa ucuugcucca ucuccaacau cgaaaccgua      720

aucgaguucc aacagaagaa caaccgccuc cucgaaauca cccgcgaguu cucugucaac      780

gcagggguca ccacucccgu cuccacauac augcucacaa acuccgaacu ccucagccuc      840

aucaacgaca ugcccauaac caacgaccag aaaaagcuaa ugagcaauaa cguccaaauc      900

guuagacaac aaaguuauuc caucaugugc aucaucaaag aagaaguccu cgccuacguc      960

guacaacucc cccucuaugg cgucaucgac acccccugcu ggaaacugca cacaucaccc     1020

cucugcacca caaacaccaa agaaggcuca aacaucugcc uaacucgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cagcguauca uucuuucccc aagccgaaac augcaaaguu     1140

caauccaacc gcgucuucug cgacacaaug aacuccagaa cgcuccccag cgaagucaac     1200

cucuguaacg uagacaucuu caacccuaag uacgacugca aaaucaugac cuccaaaacu     1260

gauguauccu ccuccgucau cacaucccug ggcgccaucg ucagcugcua cggcaaaaca     1320

aaaugcacug ccucaaacaa augccgaggu aucauaaaga ccuucucaaa cggaugcgau     1380

uacgucagca acaaaggcgu cgacaccguc agugucggca acacccucua cuacgucaac     1440

aaacaagaag gaaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccagcgacga guucgacgcc uccaucucac aagucaacga aaagauaaac     1560

caaucucuag ccuucauccg caaauccgau gaacuccugc auaacgucaa cgccggcaaa     1620

uccaccacaa acaucaugau cacuaccaua aucaucguca uaaucguaau ccuccuaucu     1680

cuuaucgcag ucggccuacu acucuacugc aaagcccgcu aaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  6032
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6032
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccgga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6033
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6033
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagcucc ugaugcaguc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccucgag      540

ggcgagguga acaagaucaa guccgcccug cugagcacca acaaggccgu ggucucccuc      600

agcgggugcg gcguguccgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag agcugcucca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccgggguca ccacgcccgu gagcaccuac augcucacca acagcgagcu gcugucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cccuguacgg cgugaucgac acgccgugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggaggggucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccgga cccuccccuc cgaggucaac     1200

cugugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu cgacacggug agcgugggga acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu guacgugaag ggggagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg uggggcuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6034
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6034
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccgca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6035
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6035
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagcuuc ugaugcaguc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu guaagguguu gcaccucgag      540

ggcgaaguua acaaaaucaa gagugcucug cuguccacga auaaagccgu ggucucucuc      600

agcgguugcg ggguguccgu auuaacuuuu aagguucugg accuuaagaa cuacauugau      660

aaacaauugc ugccuauccu aaauaagcag ucauguagua uuagcaacau cgagaccgug      720

auagaguucc agcagaaaaa uaacaggcuc cuggaaauua cacgggaguu uucugucaau      780

gcgggaguga cuaccccagu guccacauau augcuuacca acucagaacu guugagccuc      840

aucaaugaca ugccgauuac gaacgaucaa aagaaacuga ugaguaacaa uguccagauc      900

guucgccagc agucuuacuc caucaugugc auuauaaagg aggaaguguu agcauaugua      960

gugcaacugc cccucuacgg cgucaucgac acuccuuguu ggaaacuuca uacaagccca     1020

cugugcacca cuaacacaaa ggagggcucg aauauuuguu ugacccgaac ggaucguggg     1080

ugguacugcg acaacgccgg aucugugucc uucuuucccc aggcugaaac cuguaagguu     1140

cagucaaaua gaguguucug cgauacaaug aacaguagaa cucugccuag cgaggucaau     1200

cucugcaacg uggacaucuu uaauccaaaa uaugauugua agauaaugac cuccaaaaca     1260

gacguaucua gcucaguuau uaccagucug ggugccaucg uguccugcua cggcaagacu     1320

aaauguacag caagcaacaa gugcaggggg aucauuaaga ccuucucuaa uggaugugau     1380

uaugucucaa acaaaggcgu ggacacuguc agugugggua auacgcuuua cuauguuaac     1440

aagcaagagg ggaaaagccu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

uugguauucc cauccgauga guuugacgcu ucuauaucgc aggucaacga gaaaaucaac     1560

cagagccucg ccuucauucg gaaguccgau gaacuguuac acaaugugaa cgcgggcaag     1620

ucaacaacca auaucaugau cacuaccauu auaaucguua uuaucgugau ucugcuaagu     1680

cucaucgccg ucggccugcu uuuguacugc aaagcacgcu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6036
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6036
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagcagaa cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6037
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6037
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagcugc ugaugcaguc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu guaagguucu ccaccuggag      540

ggggaaguga acaaaaucaa gagcgcccuu cugucuacca auaaagcugu cgugucccuc      600

agcggaugcg gcguuucugu gcugacauuu aagguccuug accugaagaa cuacauugau      660

aaacaacucc ugccuauccu gaauaagcag uccuguagca uuucuaacau cgagaccgug      720

auugaguucc agcagaaaaa uaaccggcuc cuggaaauca cgcgcgaguu uuccgugaau      780

gccggcguca caaccccggu uagcacauau augcuuacca acuccgaacu gcucucucug      840

aucaaugaca ugcccauuac caacgaucaa aagaaacuua ugagcaacaa ugugcagauc      900

gugagacagc aguccuacag cauuaugugc aucauuaagg aggaaguccu ggcuuaugug      960

guucaacucc cucuguacgg ggugaucgac acacccuguu ggaaacugca uacgucuccu     1020

cucugcacca caaacaccaa ggagggaucc aauaucuguc ugacacggac cgaucgcggc     1080

ugguacugcg acaacgccgg gagcgucucu uucuuucccc aggcggaaac guguaaggug     1140

cagagcaaua gaguuuucug cgauacaaug aacuccagaa cccugccuuc ugaggugaau     1200

cucugcaacg ucgacauuuu uaauccgaaa uaugauugua agaucaugac cagcaaaaca     1260

gacgugucca gcucugucau uaccucccug ggagccaucg ugagcugcua cggcaagaca     1320

aaauguacgg cuucuaacaa gugccggggg auuaucaaga ccuucuccaa uggaugugau     1380

uauguuagca acaaaggcgu ggacacaguc uccgugggca auacccuuua cuauguuaac     1440

aagcaagagg ggaaaucucu guacgugaag ggagaaccca ucauuaauuu uuaugacccu     1500

cucgucuucc ccagcgauga guuugacgcc uccaucucuc aggugaacga gaaaauuaac     1560

cagagccugg cuuucauccg caaguccgau gaacugcucc acaaugugaa cgccggcaag     1620

agcacaacca auauuaugau cacgaccauu aucaucguua uuaucgucau ucugcuuucu     1680

cugaucgccg uggggcuccu gcuguacugc aaagcuagau gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6038
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6038
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuuuuaauac ugaaagcaaa ugccaucaca accauacuaa cugccgucac auucugcuuu      240

gcaucaggac aaaacauaac agaagaauuu uaccaaucca caugcucagc aguaucaaaa      300

ggauaucuau cggcacuuag aacuggaugg uacacaagug uuauaacuau agaacucuca      360

aacauaaaag aaaacaaaug caauggaaca gacgcaaaag uaaaacuaau aaaacaagaa      420

cucgauaaau auaaaaaugc aguaaccgaa cuacaacuau uaaugcaaag cacacccgca      480

acaggcagcg gaucagcaau agcaagcgga gucgcaguau guaaaguacu acaucuagaa      540

ggagaaguca acaaaaucaa aucugcacuu cuauccacaa acaaagcugu aguaucccua      600

uccggaugcg gagucucagu auuaacuuuu aaaguacuag accuuaaaaa cuacauagau      660

aaacaacuau uaccaauacu aaauaaacaa ucaugcagca uauccaauau agagacagua      720

auugaauuuc aacaaaaaaa caacagauua cuagaaauua cucgugaauu uuccguaaau      780

gccggaguca caacaccagu aucaaccuau augcuaacaa acagcgaacu acuuagcuua      840

auaaaugaca ugccaauaac aaaugaccaa aaaaaacuua ugucaaauaa cguacaaauc      900

gucagacaac aauccuacuc uauaaugugu auaauuaaag aagaaguccu agcauacgua      960

guucaauuac cacucuaugg aguaauagau acaccaugcu ggaaacuaca cacgucacca     1020

cuauguacaa caaacacaaa agaaggaucc aauauaugcc uaacaagaac cgacagaggc     1080

ugguauugug acaacgcagg auccguuuca uucuucccac aagcagaaac cuguaaagua     1140

caaucuaaua gaguauuuug cgacacaaug aacaguagaa cacuaccaag cgagguuaau     1200

cuauguaacg uagacauauu caauccaaaa uaugauugca aaauaaugac aucaaaaaca     1260

gauguaucgu cgaguguaau aacaagucug ggagcuauag uaagcugcua cggcaagacg     1320

aaauguaccg cuucaaauaa augcagagga aucauuaaaa cauucucgaa cggaugcgac     1380

uacguaagua auaaaggugu cgacaccgua ucaguaggga auacauuaua cuacgucaac     1440

aaacaagaag gaaaaucucu auauguaaaa ggagaaccaa uaauaaauuu cuaugacccu     1500

cuaguauucc caucagauga auuugacgcu uccauaucac aaguaaacga aaaaaucaau     1560

caaucuuuag cauucauacg aaaaagugau gaacuccuac acaacgucaa cgcaggaaaa     1620

agcacaacaa auauaaugau cacaacaauc aucauaguaa uaauaguaau acuacuauca     1680

uuaauagcag uaggauuauu gcuuuacugc aaagcacgau agggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6039
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6039
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acaauacuca ccgccguaac cuucugcuuu      240

gcgucgggac aaaacaucac cgaagaguuc uaccaaucca cuugcuccgc aguaagcaaa      300

ggauaccucu ccgcccugcg aaccgguugg uacacaucag ucaucacaau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcacc gacgcaaagg ucaaauuaau caagcaagaa      420

cuagacaaau acaaaaacgc cgucacagaa cuccagcugc uaaugcagag cacacccgca      480

acuggcagcg gauccgccau cgcaucagga gucgccgugu gcaaaguccu acaccucgaa      540

ggagaaguga acaaaaucaa aucagcccua cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gugucuccgu ccuaaccuuc aaagugcuag accucaagaa cuacaucgac      660

aaacaacucc uaccaauacu caacaagcaa ucuugcucca ucuccaacau cgaaaccgua      720

aucgaguucc aacagaagaa caaccgccuc cucgaaauca cccgcgaguu cucugucaac      780

gcagggguca ccacucccgu cuccacauac augcucacaa acuccgaacu ccucagccuc      840

aucaacgaca ugcccauaac caacgaccag aaaaagcuaa ugagcaauaa cguccaaauc      900

guuagacaac aaaguuauuc caucaugugc aucaucaaag aagaaguccu cgccuacguc      960

guacaacucc cccucuaugg cgucaucgac acccccugcu ggaaacugca cacaucaccc     1020

cucugcacca caaacaccaa agaaggcuca aacaucugcc uaacucgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cagcguauca uucuuucccc aagccgaaac augcaaaguu     1140

caauccaacc gcgucuucug cgacacaaug aacuccagaa cgcuccccag cgaagucaac     1200

cucuguaacg uagacaucuu caacccuaag uacgacugca aaaucaugac cuccaaaacu     1260

gauguauccu ccuccgucau cacaucccug ggcgccaucg ucagcugcua cggcaaaaca     1320

aaaugcacug ccucaaacaa augccgaggu aucauaaaga ccuucucaaa cggaugcgau     1380

uacgucagca acaaaggcgu cgacaccguc agugucggca acacccucua cuacgucaac     1440

aaacaagaag gaaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccagcgacga guucgacgcc uccaucucac aagucaacga aaagauaaac     1560

caaucucuag ccuucauccg caaauccgau gaacuccugc auaacgucaa cgccggcaaa     1620

uccaccacaa acaucaugau cacuaccaua aucaucguca uaaucguaau ccuccuaucu     1680

cuuaucgcag ucggccuacu acucuacugc aaagcccgcu aaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6040
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6040
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ggacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6041
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6041
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcagc uccugaugca guccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggcgagg ugaacaagau caaguccgcc cugcugagca ccaacaaggc cguggucucc      480

cucagcgggu gcggcguguc cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag cagagcugcu ccaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccgggg ucaccacgcc cgugagcacc uacaugcuca ccaacagcga gcugcugucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccccugua cggcgugauc gacacgccgu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggg uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ggacccuccc cuccgagguc     1080

aaccugugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1200

accaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cgucgacacg gugagcgugg ggaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccuguacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccguggggcu ccugcuguac ugcaaggccc ggugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6042
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6042
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc gcacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6043
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6043
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcagc uucugaugca gucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucuguaaggu guugcaccuc      420

gagggcgaag uuaacaaaau caagagugcu cugcugucca cgaauaaagc cguggucucu      480

cucagcgguu gcgggguguc cguauuaacu uuuaagguuc uggaccuuaa gaacuacauu      540

gauaaacaau ugcugccuau ccuaaauaag cagucaugua guauuagcaa caucgagacc      600

gugauagagu uccagcagaa aaauaacagg cuccuggaaa uuacacggga guuuucuguc      660

aaugcgggag ugacuacccc aguguccaca uauaugcuua ccaacucaga acuguugagc      720

cucaucaaug acaugccgau uacgaacgau caaaagaaac ugaugaguaa caauguccag      780

aucguucgcc agcagucuua cuccaucaug ugcauuauaa aggaggaagu guuagcauau      840

guagugcaac ugccccucua cggcgucauc gacacuccuu guuggaaacu ucauacaagc      900

ccacugugca ccacuaacac aaaggagggc ucgaauauuu guuugacccg aacggaucgu      960

gggugguacu gcgacaacgc cggaucugug uccuucuuuc cccaggcuga aaccuguaag     1020

guucagucaa auagaguguu cugcgauaca augaacagua gaacucugcc uagcgagguc     1080

aaucucugca acguggacau cuuuaaucca aaauaugauu guaagauaau gaccuccaaa     1140

acagacguau cuagcucagu uauuaccagu cugggugcca ucguguccug cuacggcaag     1200

acuaaaugua cagcaagcaa caagugcagg gggaucauua agaccuucuc uaauggaugu     1260

gauuaugucu caaacaaagg cguggacacu gucagugugg guaauacgcu uuacuauguu     1320

aacaagcaag aggggaaaag ccuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccuuugguau ucccauccga ugaguuugac gcuucuauau cgcaggucaa cgagaaaauc     1440

aaccagagcc ucgccuucau ucggaagucc gaugaacugu uacacaaugu gaacgcgggc     1500

aagucaacaa ccaauaucau gaucacuacc auuauaaucg uuauuaucgu gauucugcua     1560

agucucaucg ccgucggccu gcuuuuguac ugcaaagcac gcugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6044
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6044
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagca gaacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6045
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6045
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccagc ugcugaugca guccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg uguguaaggu ucuccaccug      420

gagggggaag ugaacaaaau caagagcgcc cuucugucua ccaauaaagc ugucgugucc      480

cucagcggau gcggcguuuc ugugcugaca uuuaaggucc uugaccugaa gaacuacauu      540

gauaaacaac uccugccuau ccugaauaag caguccugua gcauuucuaa caucgagacc      600

gugauugagu uccagcagaa aaauaaccgg cuccuggaaa ucacgcgcga guuuuccgug      660

aaugccggcg ucacaacccc gguuagcaca uauaugcuua ccaacuccga acugcucucu      720

cugaucaaug acaugcccau uaccaacgau caaaagaaac uuaugagcaa caaugugcag      780

aucgugagac agcaguccua cagcauuaug ugcaucauua aggaggaagu ccuggcuuau      840

gugguucaac ucccucugua cggggugauc gacacacccu guuggaaacu gcauacgucu      900

ccucucugca ccacaaacac caaggaggga uccaauaucu gucugacacg gaccgaucgc      960

ggcugguacu gcgacaacgc cgggagcguc ucuuucuuuc cccaggcgga aacguguaag     1020

gugcagagca auagaguuuu cugcgauaca augaacucca gaacccugcc uucugaggug     1080

aaucucugca acgucgacau uuuuaauccg aaauaugauu guaagaucau gaccagcaaa     1140

acagacgugu ccagcucugu cauuaccucc cugggagcca ucgugagcug cuacggcaag     1200

acaaaaugua cggcuucuaa caagugccgg gggauuauca agaccuucuc caauggaugu     1260

gauuauguua gcaacaaagg cguggacaca gucuccgugg gcaauacccu uuacuauguu     1320

aacaagcaag aggggaaauc ucuguacgug aagggagaac ccaucauuaa uuuuuaugac     1380

ccucucgucu uccccagcga ugaguuugac gccuccaucu cucaggugaa cgagaaaauu     1440

aaccagagcc uggcuuucau ccgcaagucc gaugaacugc uccacaaugu gaacgccggc     1500

aagagcacaa ccaauauuau gaucacgacc auuaucaucg uuauuaucgu cauucugcuu     1560

ucucugaucg ccguggggcu ccugcuguac ugcaaagcua gaugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6046
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6046
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuuuuaa uacugaaagc aaaugccauc acaaccauac uaacugccgu cacauucugc      120

uuugcaucag gacaaaacau aacagaagaa uuuuaccaau ccacaugcuc agcaguauca      180

aaaggauauc uaucggcacu uagaacugga ugguacacaa guguuauaac uauagaacuc      240

ucaaacauaa aagaaaacaa augcaaugga acagacgcaa aaguaaaacu aauaaaacaa      300

gaacucgaua aauauaaaaa ugcaguaacc gaacuacaac uauuaaugca aagcacaccc      360

gcaacaggca gcggaucagc aauagcaagc ggagucgcag uauguaaagu acuacaucua      420

gaaggagaag ucaacaaaau caaaucugca cuucuaucca caaacaaagc uguaguaucc      480

cuauccggau gcggagucuc aguauuaacu uuuaaaguac uagaccuuaa aaacuacaua      540

gauaaacaac uauuaccaau acuaaauaaa caaucaugca gcauauccaa uauagagaca      600

guaauugaau uucaacaaaa aaacaacaga uuacuagaaa uuacucguga auuuuccgua      660

aaugccggag ucacaacacc aguaucaacc uauaugcuaa caaacagcga acuacuuagc      720

uuaauaaaug acaugccaau aacaaaugac caaaaaaaac uuaugucaaa uaacguacaa      780

aucgucagac aacaauccua cucuauaaug uguauaauua aagaagaagu ccuagcauac      840

guaguucaau uaccacucua uggaguaaua gauacaccau gcuggaaacu acacacguca      900

ccacuaugua caacaaacac aaaagaagga uccaauauau gccuaacaag aaccgacaga      960

ggcugguauu gugacaacgc aggauccguu ucauucuucc cacaagcaga aaccuguaaa     1020

guacaaucua auagaguauu uugcgacaca augaacagua gaacacuacc aagcgagguu     1080

aaucuaugua acguagacau auucaaucca aaauaugauu gcaaaauaau gacaucaaaa     1140

acagauguau cgucgagugu aauaacaagu cugggagcua uaguaagcug cuacggcaag     1200

acgaaaugua ccgcuucaaa uaaaugcaga ggaaucauua aaacauucuc gaacggaugc     1260

gacuacguaa guaauaaagg ugucgacacc guaucaguag ggaauacauu auacuacguc     1320

aacaaacaag aaggaaaauc ucuauaugua aaaggagaac caauaauaaa uuucuaugac     1380

ccucuaguau ucccaucaga ugaauuugac gcuuccauau cacaaguaaa cgaaaaaauc     1440

aaucaaucuu uagcauucau acgaaaaagu gaugaacucc uacacaacgu caacgcagga     1500

aaaagcacaa caaauauaau gaucacaaca aucaucauag uaauaauagu aauacuacua     1560

ucauuaauag caguaggauu auugcuuuac ugcaaagcac gauagggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6047
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6047
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgccaua accacaauac ucaccgccgu aaccuucugc      120

uuugcgucgg gacaaaacau caccgaagag uucuaccaau ccacuugcuc cgcaguaagc      180

aaaggauacc ucuccgcccu gcgaaccggu ugguacacau cagucaucac aaucgaacuc      240

ucaaacauaa aagaaaacaa augcaacggc accgacgcaa aggucaaauu aaucaagcaa      300

gaacuagaca aauacaaaaa cgccgucaca gaacuccagc ugcuaaugca gagcacaccc      360

gcaacuggca gcggauccgc caucgcauca ggagucgccg ugugcaaagu ccuacaccuc      420

gaaggagaag ugaacaaaau caaaucagcc cuacucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggugucuc cguccuaacc uucaaagugc uagaccucaa gaacuacauc      540

gacaaacaac uccuaccaau acucaacaag caaucuugcu ccaucuccaa caucgaaacc      600

guaaucgagu uccaacagaa gaacaaccgc cuccucgaaa ucacccgcga guucucuguc      660

aacgcagggg ucaccacucc cgucuccaca uacaugcuca caaacuccga acuccucagc      720

cucaucaacg acaugcccau aaccaacgac cagaaaaagc uaaugagcaa uaacguccaa      780

aucguuagac aacaaaguua uuccaucaug ugcaucauca aagaagaagu ccucgccuac      840

gucguacaac ucccccucua uggcgucauc gacacccccu gcuggaaacu gcacacauca      900

ccccucugca ccacaaacac caaagaaggc ucaaacaucu gccuaacucg caccgaccgc      960

ggcugguacu gcgacaacgc cggcagcgua ucauucuuuc cccaagccga aacaugcaaa     1020

guucaaucca accgcgucuu cugcgacaca augaacucca gaacgcuccc cagcgaaguc     1080

aaccucugua acguagacau cuucaacccu aaguacgacu gcaaaaucau gaccuccaaa     1140

acugauguau ccuccuccgu caucacaucc cugggcgcca ucgucagcug cuacggcaaa     1200

acaaaaugca cugccucaaa caaaugccga gguaucauaa agaccuucuc aaacggaugc     1260

gauuacguca gcaacaaagg cgucgacacc gucagugucg gcaacacccu cuacuacguc     1320

aacaaacaag aaggaaaauc ccucuacguc aaaggcgaac ccaucaucaa cuucuacgac     1380

ccccucgucu uccccagcga cgaguucgac gccuccaucu cacaagucaa cgaaaagaua     1440

aaccaaucuc uagccuucau ccgcaaaucc gaugaacucc ugcauaacgu caacgccggc     1500

aaauccacca caaacaucau gaucacuacc auaaucaucg ucauaaucgu aauccuccua     1560

ucucuuaucg cagucggccu acuacucuac ugcaaagccc gcuaaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  6048
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6048
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcuccau cagcaacauc gagacgguga      600

ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc agcgugaacg      660

ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc cugucccuga      720

ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gcguacgugg      840

uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac acgagccccc      900

ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc gaccggggcu      960

gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc ugcaaggugc     1020

agagcaaccg cguguucugc gacaccauga acucccggac gcugcccagc gagguaaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac ggcaagacga     1200

agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac uacgugaaca     1320

agcaggaggg caagagccuc uacgugaagg gggagcccau caucaacuuc uacgacccgc     1380

uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag aagaucaacc     1440

agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac gccggcaaga     1500

gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc cugcuguccc     1560

ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6049
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6049
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagcuccu gaugcagucc acccccgcca      360

ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug caccucgagg      420

gcgaggugaa caagaucaag uccgcccugc ugagcaccaa caaggccgug gucucccuca      480

gcgggugcgg cguguccgug cugacguuca agguccugga ccucaagaac uacaucgaca      540

agcagcugcu gccgauccuc aacaagcaga gcugcuccau cagcaacauc gagaccguga      600

ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc uccgugaacg      660

ccggggucac cacgcccgug agcaccuaca ugcucaccaa cagcgagcug cugucccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

uccagcuccc ccuguacggc gugaucgaca cgccgugcug gaagcugcac accagccccc      900

ucugcaccac caacacgaag gaggggucca acaucugccu gacccgcacc gaccggggcu      960

gguacugcga caacgcgggc uccgugagcu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cguguucugc gacacgauga acagccggac ccuccccucc gaggucaacc     1080

ugugcaacgu ggacaucuuc aacccgaagu acgacugcaa gaucaugacc agcaagaccg     1140

acguguccag cuccgucauc acgagccugg gggccaucgu guccugcuac ggcaagacca     1200

agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caagggcguc gacacgguga gcguggggaa cacccucuac uacgucaaca     1320

agcaggaggg caagucccug uacgugaagg gggagcccau caucaacuuc uacgaccccc     1380

ugguguuccc cagcgacgag uucgacgccu ccaucagcca ggucaacgag aagaucaacc     1440

agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac gccggcaagu     1500

ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc cuccugagcc     1560

ugaucgccgu ggggcuccug cuguacugca aggcccggug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6050
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6050
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac uacaucgaca      540

agcagcuccu ccccauccuc aacaagcagu ccugcuccau cuccaacauc gagaccguca      600

ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg      660

ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc cucucccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac guccagaucg      780

uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc gccuacgucg      840

uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac accucccccc      900

ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc gaccgcggcu      960

gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cgucuucugc gacaccauga acucccgcac ccuccccucc gaggucaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac ggcaagacca     1200

agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac ggcugcgacu     1260

acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac uacgucaaca     1320

agcaggaggg caagucccuc uacgucaagg gcgagcccau caucaacuuc uacgaccccc     1380

ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag aagaucaacc     1440

agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac gccggcaagu     1500

ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc cuccucuccc     1560

ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6051
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6051
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagcuucu gaugcagucu acacccgcca      360

ccggcucggg gucagcuaua gcaagcggag uggccgucug uaagguguug caccucgagg      420

gcgaaguuaa caaaaucaag agugcucugc uguccacgaa uaaagccgug gucucucuca      480

gcgguugcgg gguguccgua uuaacuuuua agguucugga ccuuaagaac uacauugaua      540

aacaauugcu gccuauccua aauaagcagu cauguaguau uagcaacauc gagaccguga      600

uagaguucca gcagaaaaau aacaggcucc uggaaauuac acgggaguuu ucugucaaug      660

cgggagugac uaccccagug uccacauaua ugcuuaccaa cucagaacug uugagccuca      720

ucaaugacau gccgauuacg aacgaucaaa agaaacugau gaguaacaau guccagaucg      780

uucgccagca gucuuacucc aucaugugca uuauaaagga ggaaguguua gcauauguag      840

ugcaacugcc ccucuacggc gucaucgaca cuccuuguug gaaacuucau acaagcccac      900

ugugcaccac uaacacaaag gagggcucga auauuuguuu gacccgaacg gaucgugggu      960

gguacugcga caacgccgga ucuguguccu ucuuucccca ggcugaaacc uguaagguuc     1020

agucaaauag aguguucugc gauacaauga acaguagaac ucugccuagc gaggucaauc     1080

ucugcaacgu ggacaucuuu aauccaaaau augauuguaa gauaaugacc uccaaaacag     1140

acguaucuag cucaguuauu accagucugg gugccaucgu guccugcuac ggcaagacua     1200

aauguacagc aagcaacaag ugcaggggga ucauuaagac cuucucuaau ggaugugauu     1260

augucucaaa caaaggcgug gacacuguca guguggguaa uacgcuuuac uauguuaaca     1320

agcaagaggg gaaaagccug uacgugaagg gagaacccau cauuaauuuu uaugacccuu     1380

ugguauuccc auccgaugag uuugacgcuu cuauaucgca ggucaacgag aaaaucaacc     1440

agagccucgc cuucauucgg aaguccgaug aacuguuaca caaugugaac gcgggcaagu     1500

caacaaccaa uaucaugauc acuaccauua uaaucguuau uaucgugauu cugcuaaguc     1560

ucaucgccgu cggccugcuu uuguacugca aagcacgcug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6052
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6052
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcagcau cagcaacauc gagaccguga      600

ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc agcgugaacg      660

ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug cugagccuga      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac accagccccc      900

ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc gacagaggcu      960

gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc ugcaaggugc     1020

agagcaacag aguguucugc gacaccauga acagcagaac ccugcccagc gaggugaacc     1080

ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc agcaagaccg     1140

acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac ggcaagacca     1200

agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac uacgugaaca     1320

agcaggaggg caagagccug uacgugaagg gcgagcccau caucaacuuc uacgaccccc     1380

ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag aagaucaacc     1440

agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac gccggcaaga     1500

gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc cugcugagcc     1560

ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6053
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6053
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagcugcu gaugcagucc acccccgcca      360

cagggucugg aagcgcuauu gccuccggcg ucgcggugug uaagguucuc caccuggagg      420

gggaagugaa caaaaucaag agcgcccuuc ugucuaccaa uaaagcuguc gugucccuca      480

gcggaugcgg cguuucugug cugacauuua agguccuuga ccugaagaac uacauugaua      540

aacaacuccu gccuauccug aauaagcagu ccuguagcau uucuaacauc gagaccguga      600

uugaguucca gcagaaaaau aaccggcucc uggaaaucac gcgcgaguuu uccgugaaug      660

ccggcgucac aaccccgguu agcacauaua ugcuuaccaa cuccgaacug cucucucuga      720

ucaaugacau gcccauuacc aacgaucaaa agaaacuuau gagcaacaau gugcagaucg      780

ugagacagca guccuacagc auuaugugca ucauuaagga ggaaguccug gcuuaugugg      840

uucaacuccc ucuguacggg gugaucgaca cacccuguug gaaacugcau acgucuccuc      900

ucugcaccac aaacaccaag gagggaucca auaucugucu gacacggacc gaucgcggcu      960

gguacugcga caacgccggg agcgucucuu ucuuucccca ggcggaaacg uguaaggugc     1020

agagcaauag aguuuucugc gauacaauga acuccagaac ccugccuucu gaggugaauc     1080

ucugcaacgu cgacauuuuu aauccgaaau augauuguaa gaucaugacc agcaaaacag     1140

acguguccag cucugucauu accucccugg gagccaucgu gagcugcuac ggcaagacaa     1200

aauguacggc uucuaacaag ugccggggga uuaucaagac cuucuccaau ggaugugauu     1260

auguuagcaa caaaggcgug gacacagucu ccgugggcaa uacccuuuac uauguuaaca     1320

agcaagaggg gaaaucucug uacgugaagg gagaacccau cauuaauuuu uaugacccuc     1380

ucgucuuccc cagcgaugag uuugacgccu ccaucucuca ggugaacgag aaaauuaacc     1440

agagccuggc uuucauccgc aaguccgaug aacugcucca caaugugaac gccggcaaga     1500

gcacaaccaa uauuaugauc acgaccauua ucaucguuau uaucgucauu cugcuuucuc     1560

ugaucgccgu ggggcuccug cuguacugca aagcuagaug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6054
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6054
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uuuuaauacu gaaagcaaau gccaucacaa ccauacuaac ugccgucaca uucugcuuug      120

caucaggaca aaacauaaca gaagaauuuu accaauccac augcucagca guaucaaaag      180

gauaucuauc ggcacuuaga acuggauggu acacaagugu uauaacuaua gaacucucaa      240

acauaaaaga aaacaaaugc aauggaacag acgcaaaagu aaaacuaaua aaacaagaac      300

ucgauaaaua uaaaaaugca guaaccgaac uacaacuauu aaugcaaagc acacccgcaa      360

caggcagcgg aucagcaaua gcaagcggag ucgcaguaug uaaaguacua caucuagaag      420

gagaagucaa caaaaucaaa ucugcacuuc uauccacaaa caaagcugua guaucccuau      480

ccggaugcgg agucucagua uuaacuuuua aaguacuaga ccuuaaaaac uacauagaua      540

aacaacuauu accaauacua aauaaacaau caugcagcau auccaauaua gagacaguaa      600

uugaauuuca acaaaaaaac aacagauuac uagaaauuac ucgugaauuu uccguaaaug      660

ccggagucac aacaccagua ucaaccuaua ugcuaacaaa cagcgaacua cuuagcuuaa      720

uaaaugacau gccaauaaca aaugaccaaa aaaaacuuau gucaaauaac guacaaaucg      780

ucagacaaca auccuacucu auaaugugua uaauuaaaga agaaguccua gcauacguag      840

uucaauuacc acucuaugga guaauagaua caccaugcug gaaacuacac acgucaccac      900

uauguacaac aaacacaaaa gaaggaucca auauaugccu aacaagaacc gacagaggcu      960

gguauuguga caacgcagga uccguuucau ucuucccaca agcagaaacc uguaaaguac     1020

aaucuaauag aguauuuugc gacacaauga acaguagaac acuaccaagc gagguuaauc     1080

uauguaacgu agacauauuc aauccaaaau augauugcaa aauaaugaca ucaaaaacag     1140

auguaucguc gaguguaaua acaagucugg gagcuauagu aagcugcuac ggcaagacga     1200

aauguaccgc uucaaauaaa ugcagaggaa ucauuaaaac auucucgaac ggaugcgacu     1260

acguaaguaa uaaagguguc gacaccguau caguagggaa uacauuauac uacgucaaca     1320

aacaagaagg aaaaucucua uauguaaaag gagaaccaau aauaaauuuc uaugacccuc     1380

uaguauuccc aucagaugaa uuugacgcuu ccauaucaca aguaaacgaa aaaaucaauc     1440

aaucuuuagc auucauacga aaaagugaug aacuccuaca caacgucaac gcaggaaaaa     1500

gcacaacaaa uauaaugauc acaacaauca ucauaguaau aauaguaaua cuacuaucau     1560

uaauagcagu aggauuauug cuuuacugca aagcacgaua gggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6055
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6055
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu caaagccaac gccauaacca caauacucac cgccguaacc uucugcuuug      120

cgucgggaca aaacaucacc gaagaguucu accaauccac uugcuccgca guaagcaaag      180

gauaccucuc cgcccugcga accgguuggu acacaucagu caucacaauc gaacucucaa      240

acauaaaaga aaacaaaugc aacggcaccg acgcaaaggu caaauuaauc aagcaagaac      300

uagacaaaua caaaaacgcc gucacagaac uccagcugcu aaugcagagc acacccgcaa      360

cuggcagcgg auccgccauc gcaucaggag ucgccgugug caaaguccua caccucgaag      420

gagaagugaa caaaaucaaa ucagcccuac ucuccaccaa caaggccguc gucucccucu      480

ccggcugcgg ugucuccguc cuaaccuuca aagugcuaga ccucaagaac uacaucgaca      540

aacaacuccu accaauacuc aacaagcaau cuugcuccau cuccaacauc gaaaccguaa      600

ucgaguucca acagaagaac aaccgccucc ucgaaaucac ccgcgaguuc ucugucaacg      660

caggggucac cacucccguc uccacauaca ugcucacaaa cuccgaacuc cucagccuca      720

ucaacgacau gcccauaacc aacgaccaga aaaagcuaau gagcaauaac guccaaaucg      780

uuagacaaca aaguuauucc aucaugugca ucaucaaaga agaaguccuc gccuacgucg      840

uacaacuccc ccucuauggc gucaucgaca cccccugcug gaaacugcac acaucacccc      900

ucugcaccac aaacaccaaa gaaggcucaa acaucugccu aacucgcacc gaccgcggcu      960

gguacugcga caacgccggc agcguaucau ucuuucccca agccgaaaca ugcaaaguuc     1020

aauccaaccg cgucuucugc gacacaauga acuccagaac gcuccccagc gaagucaacc     1080

ucuguaacgu agacaucuuc aacccuaagu acgacugcaa aaucaugacc uccaaaacug     1140

auguauccuc cuccgucauc acaucccugg gcgccaucgu cagcugcuac ggcaaaacaa     1200

aaugcacugc cucaaacaaa ugccgaggua ucauaaagac cuucucaaac ggaugcgauu     1260

acgucagcaa caaaggcguc gacaccguca gugucggcaa cacccucuac uacgucaaca     1320

aacaagaagg aaaaucccuc uacgucaaag gcgaacccau caucaacuuc uacgaccccc     1380

ucgucuuccc cagcgacgag uucgacgccu ccaucucaca agucaacgaa aagauaaacc     1440

aaucucuagc cuucauccgc aaauccgaug aacuccugca uaacgucaac gccggcaaau     1500

ccaccacaaa caucaugauc acuaccauaa ucaucgucau aaucguaauc cuccuaucuc     1560

uuaucgcagu cggccuacua cucuacugca aagcccgcua aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6056
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1) R7457

<400>  6056
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccggcugc ggcgucagcg ugcugaccuu caaggugcug      480

gaccucaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcucc      540

aucagcaaca ucgagacggu gaucgaguuc cagcagaaga acaaccggcu ccuggagauc      600

acccgcgagu ucagcgugaa cgccgggguc accacccccg uguccacgua caugcugacc      660

aacagcgagc uccugucccu gaucaacgac augccgauca ccaacgacca gaagaagcuc      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggcguacgu gguccagcug ccccucuacg gcgugaucga cacccccugc      840

uggaagcugc acacgagccc ccugugcacc accaacacca aggagggguc caacaucugc      900

cucacgcgca ccgaccgggg cugguacugc gacaacgccg gcagcgucuc cuucuucccg      960

caggccgaga ccugcaaggu gcagagcaac cgcguguucu gcgacaccau gaacucccgg     1020

acgcugccca gcgagguaaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgugagc uccagcguga ucaccucccu gggggccauc     1140

gucagcugcu acggcaagac gaagugcacc gccagcaaca agugccgggg gaucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaagggcg uggacaccgu guccgucggg     1260

aacacccugu acuacgugaa caagcaggag ggcaagagcc ucuacgugaa gggggagccc     1320

aucaucaacu ucuacgaccc gcuggucuuc cccuccgacg aguucgacgc gagcaucucc     1380

caggugaacg agaagaucaa ccagagccug gccuucaucc gcaaguccga cgagcugcuc     1440

cacaacguga acgccggcaa gagcacgacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguga uccugcuguc ccucaucgcc guggggcugc ugcucuacug caaggcccgg     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6057
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt1)

<400>  6057
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagcuc      300

cugaugcagu ccacccccgc caccggcagc ggguccgcca ucgccagcgg cguggcggug      360

ugcaaggucc ugcaccucga gggcgaggug aacaagauca aguccgcccu gcugagcacc      420

aacaaggccg uggucucccu cagcgggugc ggcguguccg ugcugacguu caagguccug      480

gaccucaaga acuacaucga caagcagcug cugccgaucc ucaacaagca gagcugcucc      540

aucagcaaca ucgagaccgu gaucgaguuc cagcagaaga acaaccggcu gcuggagauc      600

acccgcgagu ucuccgugaa cgccgggguc accacgcccg ugagcaccua caugcucacc      660

aacagcgagc ugcugucccu caucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu gguccagcuc ccccuguacg gcgugaucga cacgccgugc      840

uggaagcugc acaccagccc ccucugcacc accaacacga aggagggguc caacaucugc      900

cugacccgca ccgaccgggg cugguacugc gacaacgcgg gcuccgugag cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcguguucu gcgacacgau gaacagccgg     1020

acccuccccu ccgaggucaa ccugugcaac guggacaucu ucaacccgaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugucc agcuccguca ucacgagccu gggggccauc     1140

guguccugcu acggcaagac caagugcacc gccagcaaca agugccgggg gaucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaagggcg ucgacacggu gagcgugggg     1260

aacacccucu acuacgucaa caagcaggag ggcaaguccc uguacgugaa gggggagccc     1320

aucaucaacu ucuacgaccc ccugguguuc cccagcgacg aguucgacgc cuccaucagc     1380

caggucaacg agaagaucaa ccagucccuc gcguucaucc gcaagagcga cgagcugcug     1440

cacaacguga acgccggcaa guccaccacc aacaucauga ucaccacgau caucaucgug     1500

aucaucguca uccuccugag ccugaucgcc guggggcucc ugcuguacug caaggcccgg     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6058
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt2)

<400>  6058
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccggcugc ggcgucuccg uccucaccuu caagguccuc      480

gaccucaaga acuacaucga caagcagcuc cuccccaucc ucaacaagca guccugcucc      540

aucuccaaca ucgagaccgu caucgaguuc cagcagaaga acaaccgccu ccucgagauc      600

acccgcgagu ucuccgucaa cgccggcguc accacccccg ucuccaccua caugcucacc      660

aacuccgagc uccucucccu caucaacgac augcccauca ccaacgacca gaagaagcuc      720

auguccaaca acguccagau cguccgccag caguccuacu ccaucaugug caucaucaag      780

gaggaggucc ucgccuacgu cguccagcuc ccccucuacg gcgucaucga cacccccugc      840

uggaagcucc acaccucccc ccucugcacc accaacacca aggagggcuc caacaucugc      900

cucacccgca ccgaccgcgg cugguacugc gacaacgccg gcuccgucuc cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcgucuucu gcgacaccau gaacucccgc     1020

acccuccccu ccgaggucaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgucucc uccuccguca ucaccucccu cggcgccauc     1140

gucuccugcu acggcaagac caagugcacc gccuccaaca agugccgcgg caucaucaag     1200

accuucucca acggcugcga cuacgucucc aacaagggcg ucgacaccgu cuccgucggc     1260

aacacccucu acuacgucaa caagcaggag ggcaaguccc ucuacgucaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccucgucuuc cccuccgacg aguucgacgc cuccaucucc     1380

caggucaacg agaagaucaa ccagucccuc gccuucaucc gcaaguccga cgagcuccuc     1440

cacaacguca acgccggcaa guccaccacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguca uccuccucuc ccucaucgcc gucggccucc uccucuacug caaggcccgc     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6059
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt3)

<400>  6059
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagcuu      300

cugaugcagu cuacacccgc caccggcucg gggucagcua uagcaagcgg aguggccguc      360

uguaaggugu ugcaccucga gggcgaaguu aacaaaauca agagugcucu gcuguccacg      420

aauaaagccg uggucucucu cagcgguugc gggguguccg uauuaacuuu uaagguucug      480

gaccuuaaga acuacauuga uaaacaauug cugccuaucc uaaauaagca gucauguagu      540

auuagcaaca ucgagaccgu gauagaguuc cagcagaaaa auaacaggcu ccuggaaauu      600

acacgggagu uuucugucaa ugcgggagug acuaccccag uguccacaua uaugcuuacc      660

aacucagaac uguugagccu caucaaugac augccgauua cgaacgauca aaagaaacug      720

augaguaaca auguccagau cguucgccag cagucuuacu ccaucaugug cauuauaaag      780

gaggaagugu uagcauaugu agugcaacug ccccucuacg gcgucaucga cacuccuugu      840

uggaaacuuc auacaagccc acugugcacc acuaacacaa aggagggcuc gaauauuugu      900

uugacccgaa cggaucgugg gugguacugc gacaacgccg gaucuguguc cuucuuuccc      960

caggcugaaa ccuguaaggu ucagucaaau agaguguucu gcgauacaau gaacaguaga     1020

acucugccua gcgaggucaa ucucugcaac guggacaucu uuaauccaaa auaugauugu     1080

aagauaauga ccuccaaaac agacguaucu agcucaguua uuaccagucu gggugccauc     1140

guguccugcu acggcaagac uaaauguaca gcaagcaaca agugcagggg gaucauuaag     1200

accuucucua auggauguga uuaugucuca aacaaaggcg uggacacugu cagugugggu     1260

aauacgcuuu acuauguuaa caagcaagag gggaaaagcc uguacgugaa gggagaaccc     1320

aucauuaauu uuuaugaccc uuugguauuc ccauccgaug aguuugacgc uucuauaucg     1380

caggucaacg agaaaaucaa ccagagccuc gccuucauuc ggaaguccga ugaacuguua     1440

cacaauguga acgcgggcaa gucaacaacc aauaucauga ucacuaccau uauaaucguu     1500

auuaucguga uucugcuaag ucucaucgcc gucggccugc uuuuguacug caaagcacgc     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6060
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt4)

<400>  6060
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcggcugc ggcgugagcg ugcugaccuu caaggugcug      480

gaccugaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcagc      540

aucagcaaca ucgagaccgu gaucgaguuc cagcagaaga acaacagacu gcuggagauc      600

accagagagu ucagcgugaa cgccggcgug accacccccg ugagcaccua caugcugacc      660

aacagcgagc ugcugagccu gaucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cgugagacag cagagcuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu ggugcagcug ccccuguacg gcgugaucga cacccccugc      840

uggaagcugc acaccagccc ccugugcacc accaacacca aggagggcag caacaucugc      900

cugaccagaa ccgacagagg cugguacugc gacaacgccg gcagcgugag cuucuucccc      960

caggccgaga ccugcaaggu gcagagcaac agaguguucu gcgacaccau gaacagcaga     1020

acccugccca gcgaggugaa ccugugcaac guggacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugagc agcagcguga ucaccagccu gggcgccauc     1140

gugagcugcu acggcaagac caagugcacc gccagcaaca agugcagagg caucaucaag     1200

accuucagca acggcugcga cuacgugagc aacaagggcg uggacaccgu gagcgugggc     1260

aacacccugu acuacgugaa caagcaggag ggcaagagcc uguacgugaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccugguguuc cccagcgacg aguucgacgc cagcaucagc     1380

caggugaacg agaagaucaa ccagagccug gccuucauca gaaagagcga cgagcugcug     1440

cacaacguga acgccggcaa gagcaccacc aacaucauga ucaccaccau caucaucgug     1500

aucaucguga uccugcugag ccugaucgcc gugggccugc ugcuguacug caaggccaga     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6061
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt5)

<400>  6061
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagcug      300

cugaugcagu ccacccccgc cacagggucu ggaagcgcua uugccuccgg cgucgcggug      360

uguaagguuc uccaccugga gggggaagug aacaaaauca agagcgcccu ucugucuacc      420

aauaaagcug ucgugucccu cagcggaugc ggcguuucug ugcugacauu uaagguccuu      480

gaccugaaga acuacauuga uaaacaacuc cugccuaucc ugaauaagca guccuguagc      540

auuucuaaca ucgagaccgu gauugaguuc cagcagaaaa auaaccggcu ccuggaaauc      600

acgcgcgagu uuuccgugaa ugccggcguc acaaccccgg uuagcacaua uaugcuuacc      660

aacuccgaac ugcucucucu gaucaaugac augcccauua ccaacgauca aaagaaacuu      720

augagcaaca augugcagau cgugagacag caguccuaca gcauuaugug caucauuaag      780

gaggaagucc uggcuuaugu gguucaacuc ccucuguacg gggugaucga cacacccugu      840

uggaaacugc auacgucucc ucucugcacc acaaacacca aggagggauc caauaucugu      900

cugacacgga ccgaucgcgg cugguacugc gacaacgccg ggagcgucuc uuucuuuccc      960

caggcggaaa cguguaaggu gcagagcaau agaguuuucu gcgauacaau gaacuccaga     1020

acccugccuu cugaggugaa ucucugcaac gucgacauuu uuaauccgaa auaugauugu     1080

aagaucauga ccagcaaaac agacgugucc agcucuguca uuaccucccu gggagccauc     1140

gugagcugcu acggcaagac aaaauguacg gcuucuaaca agugccgggg gauuaucaag     1200

accuucucca auggauguga uuauguuagc aacaaaggcg uggacacagu cuccgugggc     1260

aauacccuuu acuauguuaa caagcaagag gggaaaucuc uguacgugaa gggagaaccc     1320

aucauuaauu uuuaugaccc ucucgucuuc cccagcgaug aguuugacgc cuccaucucu     1380

caggugaacg agaaaauuaa ccagagccug gcuuucaucc gcaaguccga ugaacugcuc     1440

cacaauguga acgccggcaa gagcacaacc aauauuauga ucacgaccau uaucaucguu     1500

auuaucguca uucugcuuuc ucugaucgcc guggggcucc ugcuguacug caaagcuaga     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6062
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt6)

<400>  6062
gggagaaagc uuaccaugga acuuuuaaua cugaaagcaa augccaucac aaccauacua       60

acugccguca cauucugcuu ugcaucagga caaaacauaa cagaagaauu uuaccaaucc      120

acaugcucag caguaucaaa aggauaucua ucggcacuua gaacuggaug guacacaagu      180

guuauaacua uagaacucuc aaacauaaaa gaaaacaaau gcaauggaac agacgcaaaa      240

guaaaacuaa uaaaacaaga acucgauaaa uauaaaaaug caguaaccga acuacaacua      300

uuaaugcaaa gcacacccgc aacaggcagc ggaucagcaa uagcaagcgg agucgcagua      360

uguaaaguac uacaucuaga aggagaaguc aacaaaauca aaucugcacu ucuauccaca      420

aacaaagcug uaguaucccu auccggaugc ggagucucag uauuaacuuu uaaaguacua      480

gaccuuaaaa acuacauaga uaaacaacua uuaccaauac uaaauaaaca aucaugcagc      540

auauccaaua uagagacagu aauugaauuu caacaaaaaa acaacagauu acuagaaauu      600

acucgugaau uuuccguaaa ugccggaguc acaacaccag uaucaaccua uaugcuaaca      660

aacagcgaac uacuuagcuu aauaaaugac augccaauaa caaaugacca aaaaaaacuu      720

augucaaaua acguacaaau cgucagacaa caauccuacu cuauaaugug uauaauuaaa      780

gaagaagucc uagcauacgu aguucaauua ccacucuaug gaguaauaga uacaccaugc      840

uggaaacuac acacgucacc acuauguaca acaaacacaa aagaaggauc caauauaugc      900

cuaacaagaa ccgacagagg cugguauugu gacaacgcag gauccguuuc auucuuccca      960

caagcagaaa ccuguaaagu acaaucuaau agaguauuuu gcgacacaau gaacaguaga     1020

acacuaccaa gcgagguuaa ucuauguaac guagacauau ucaauccaaa auaugauugc     1080

aaaauaauga caucaaaaac agauguaucg ucgaguguaa uaacaagucu gggagcuaua     1140

guaagcugcu acggcaagac gaaauguacc gcuucaaaua aaugcagagg aaucauuaaa     1200

acauucucga acggaugcga cuacguaagu aauaaaggug ucgacaccgu aucaguaggg     1260

aauacauuau acuacgucaa caaacaagaa ggaaaaucuc uauauguaaa aggagaacca     1320

auaauaaauu ucuaugaccc ucuaguauuc ccaucagaug aauuugacgc uuccauauca     1380

caaguaaacg aaaaaaucaa ucaaucuuua gcauucauac gaaaaaguga ugaacuccua     1440

cacaacguca acgcaggaaa aagcacaaca aauauaauga ucacaacaau caucauagua     1500

auaauaguaa uacuacuauc auuaauagca guaggauuau ugcuuuacug caaagcacga     1560

uagggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6063
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut5 (opt11)

<400>  6063
gggagaaagc uuaccaugga acuccucauc cucaaagcca acgccauaac cacaauacuc       60

accgccguaa ccuucugcuu ugcgucggga caaaacauca ccgaagaguu cuaccaaucc      120

acuugcuccg caguaagcaa aggauaccuc uccgcccugc gaaccgguug guacacauca      180

gucaucacaa ucgaacucuc aaacauaaaa gaaaacaaau gcaacggcac cgacgcaaag      240

gucaaauuaa ucaagcaaga acuagacaaa uacaaaaacg ccgucacaga acuccagcug      300

cuaaugcaga gcacacccgc aacuggcagc ggauccgcca ucgcaucagg agucgccgug      360

ugcaaagucc uacaccucga aggagaagug aacaaaauca aaucagcccu acucuccacc      420

aacaaggccg ucgucucccu cuccggcugc ggugucuccg uccuaaccuu caaagugcua      480

gaccucaaga acuacaucga caaacaacuc cuaccaauac ucaacaagca aucuugcucc      540

aucuccaaca ucgaaaccgu aaucgaguuc caacagaaga acaaccgccu ccucgaaauc      600

acccgcgagu ucucugucaa cgcagggguc accacucccg ucuccacaua caugcucaca      660

aacuccgaac uccucagccu caucaacgac augcccauaa ccaacgacca gaaaaagcua      720

augagcaaua acguccaaau cguuagacaa caaaguuauu ccaucaugug caucaucaaa      780

gaagaagucc ucgccuacgu cguacaacuc ccccucuaug gcgucaucga cacccccugc      840

uggaaacugc acacaucacc ccucugcacc acaaacacca aagaaggcuc aaacaucugc      900

cuaacucgca ccgaccgcgg cugguacugc gacaacgccg gcagcguauc auucuuuccc      960

caagccgaaa caugcaaagu ucaauccaac cgcgucuucu gcgacacaau gaacuccaga     1020

acgcucccca gcgaagucaa ccucuguaac guagacaucu ucaacccuaa guacgacugc     1080

aaaaucauga ccuccaaaac ugauguaucc uccuccguca ucacaucccu gggcgccauc     1140

gucagcugcu acggcaaaac aaaaugcacu gccucaaaca aaugccgagg uaucauaaag     1200

accuucucaa acggaugcga uuacgucagc aacaaaggcg ucgacaccgu cagugucggc     1260

aacacccucu acuacgucaa caaacaagaa ggaaaauccc ucuacgucaa aggcgaaccc     1320

aucaucaacu ucuacgaccc ccucgucuuc cccagcgacg aguucgacgc cuccaucuca     1380

caagucaacg aaaagauaaa ccaaucucua gccuucaucc gcaaauccga ugaacuccug     1440

cauaacguca acgccggcaa auccaccaca aacaucauga ucacuaccau aaucaucguc     1500

auaaucguaa uccuccuauc ucuuaucgca gucggccuac uacucuacug caaagcccgc     1560

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  6064
<211>  535
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6064

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Met Leu 
                85                  90                  95      


Met Cys Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Pro Glu Thr Val Met Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Cys Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Lys Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Tyr Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly Ile 
        515                 520                 525             


Asn Asn Ile Ala Phe Ser Asn 
    530                 535 


<210>  6065
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6065
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agaugcugau gugcuccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa ccccgagacg      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugugcagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaacaag gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1560

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacuga                  1608


<210>  6066
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6066
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agaugcucau gugcagcacc      300

cccgccaccg gguccggcag cgccaucgcc uccggcgugg cggugugcaa gguccugcac      360

cuggaggggg aggugaacaa gaucaagagc gcccuccugu ccaccaacaa ggccgugguc      420

agccugucca acggcgugag cgugcucacg uucaaggucc uggaccugaa gaacuacauc      480

gacaagcagc uccugccgau ccugaacaag caguccugca gcauccccaa ccccgagacc      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuga ccaacuccga gcuccugagc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ugccccucua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac gaaggagggg agcaacaucu gccucacccg caccgaccgg      900

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cgcaggccga gaccugcaag      960

gucugcucca accgcguguu cugcgacacg augaacagcc ugacccugcc cuccgagguc     1020

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaag gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu guacuacguc     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc uggcguucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccugcuc     1500

agccugaucg ccguggggcu gcuccuguac ugcaaggccc gcuccacccc cgugacccug     1560

agcaaggacc agcuguccgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  6067
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6067
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agaugcucau gugcuccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa ccccgagacc      540

gucauggagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

gucugcucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaacaag ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1560

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacuga                  1608


<210>  6068
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6068
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugaccugc agaugcuuau guguuccaca      300

cccgccaccg ggucuggauc ggcuauagca ucaggcgugg ccgucugcaa ggugcugcac      360

uuggagggug agguuaacaa aaucaagagc gcucuccuga guacgaauaa agccgugguc      420

ucccugucua acggggugag cguacucacu uuuaagguuu uagaucugaa gaauuacauu      480

gacaaacagc uuuugccuau ccugaacaag caauccuguu caauuccaaa uccggaaacc      540

gugauggagu uccagcagaa aaacaauagg cuacucgaaa ucacacggga guuuaguguc      600

aacgcgggag ugacuacccc cgugagcaca uauaugcuga ccaauucuga gcuucugucc      660

uugauaaacg auaugccuau uacgaacgac cagaagaaac ucaugucaaa uaacguccaa      720

aucguucgcc agcagagcua caguauuaug ugcaucauca aggaagaggu gcuggcauau      780

guagugcagu uaccacugua cggcgucauu gauacucccu guuggaaacu ccauacaucu      840

ccucuuugca ccacuaauac aaaggaaggc uccaacauau gucugacccg aacggaccgu      900

gggugguacu gcgauaaugc cggaagcgug ucguucuuuc cacaagcuga gaccuguaag      960

guuugcucua acagaguguu cugcgacaca augaacuccu ugacucuacc cucagaaguc     1020

aaucugugua auguggauau cuuuaacccu aaauaugacu gcaagauuau gaccaguaaa     1080

acagauguaa gcuccucugu uaucacuagc cucggugcca uagugucaug uuacggcaag     1140

accaaaugca cagcaaguaa uaagaacaag gggauuauca aaaccuucuc caauggaugu     1200

gacuauguca gcaacaaggg cguggacacu gucucugugg guaauacgcu guacuauguu     1260

aacaaacagg aggggcaguc acuuuacgug aagggagagc caaucauuaa cuuuuaugau     1320

ccgcugguau uccccaguga cgaauuugau gcuagcaucu cccaagucaa ugagaaaauu     1380

aaccagucuu uggccuucau aaggaagucg gacgaacucc ugcacaaugu gaacgcgggc     1440

aagagcacaa ccaauaucau gauuacuacc aucaucauug uuauaaucgu gauuuuacug     1500

ucccuaaucg ccgucggccu ccugcuuuac ugcaaagcac ggucaacacc ugugaccuug     1560

aguaaggauc agcugucugg gauuaacaau aucgcuuuca gcaacuga                  1608


<210>  6069
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6069
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agaugcugau gugcagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa ccccgagacc      540

gugauggagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugugcagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaag ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1560

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  6070
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6070
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagaa uaaaugcaac gggaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggaccucc agaugcugau guguagcacc      300

cccgccacag gauccggcuc ugcuauugcc agcggggucg cggugugcaa gguucugcac      360

cucgagggag aggugaacaa aaucaagucc gcccugcuua gcaccaauaa agcugucgug      420

ucucugucca acggcguuag cgugcucaca uuuaaggucc uggaucuuaa gaauuacauu      480

gacaaacagc ugcucccuau ccugaacaag caaucuuguu ccauuccgaa ucccgaaacc      540

gugauggagu uccagcagaa aaacaaucgg cugcucgaaa ucacgcgcga guuuagcgug      600

aacgccggcg ucacaacccc uguuucuaca uauaugcuga ccaauuccga gcuucugagc      660

cucauuaacg auaugcccau caccaacgac cagaagaaac ugauguccaa uaacgugcaa      720

aucgugagac agcagucuua cagcauuaug ugcaucauua aggaagaggu ccuugcuuau      780

gugguucagc ugccucucua cggggugauc gauacacccu guuggaaacu gcauacgucc      840

ccucugugca ccacaaauac caaggaagga agcaacauuu gucucacacg gaccgaccgc      900

ggcugguacu gcgauaaugc cgggucuguc uccuucuuuc cgcaagcgga gacguguaag      960

gugugcagca acagaguuuu cugcgacaca augaacucuc ugacccuucc cagcgaagug     1020

aaucugugua augucgauau cuuuaacccu aaauaugacu gcaagaucau gaccuccaaa     1080

acagaugugu cuagcuccgu cauuaccagc cucggagcca ucgugucuug uuacggcaag     1140

acaaaaugca cggcuuccaa uaagaacaag gggauuauca aaaccuucag caauggaugu     1200

gacuauguuu cuaacaaggg cguggacaca gucuccgugg gcaauacccu guacuauguu     1260

aacaaacagg aggggcagag ccuuuacgug aagggagagc ccauuaucaa cuuuuaugau     1320

ccucuggucu uccccuccga cgaauuugau gccucuauca gccaagugaa ugagaaaauu     1380

aaccaguccc ucgcuuucau ccggaagucu gacgaacugc ugcacaaugu gaacgccggc     1440

aagagcacaa ccaauauuau gaucacgacc auuaucauug uuaucaucgu cauucuccug     1500

ucccuuaucg ccguggggcu gcuccuguac ugcaaagcuc gcagcacacc ggugacccug     1560

ucuaaggauc agcuuuccgg aauuaacaau aucgcguuca gcaacuga                  1608


<210>  6071
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6071
auggaacuau uaaucuuaaa agcaaaugcu auaaccacaa uauuaacagc aguaacauuc       60

uguuuugccu ccggacaaaa cauaacagaa gaauuuuauc aaucaacaug cucugcagua      120

uccaaagguu acuuaggcgc acuacgcacu ggaugguaua caucaguaau aacaauagaa      180

cuaucaaaca uaaaagaaaa uaaauguaac gguacugacg caaaagugaa acuaauuaaa      240

caagaacucg acaaauacaa aaaugcugua acagaccuac aaaugcuaau gugcucaaca      300

cccgcaaccg gaucaggauc agccauagcc uccggagucg caguaugcaa aguauuacau      360

cuugaaggag aaguaaauaa aauaaaauca gcauuacuau ccacaaauaa agccguagua      420

ucacuaucaa acgguguauc cguccuuaca uucaaaguau uagaucuaaa aaacuacaua      480

gauaaacaac uacuacccau cuuaaacaaa caaucaugcu caauucccaa cccagaaaca      540

gucauggaau uucaacaaaa aaacaacaga cucuuagaaa uaacacgaga auuuucagua      600

aacgcaggag uaaccacacc aguaaguaca uacaugcuca ccaacucaga auuauuauca      660

cuuauuaacg acaugccaau uacaaacgac caaaaaaaau uaaugucaaa caauguccaa      720

auuguuagac aacaaucaua cucuauaaug uguauaauaa aagaagaagu acuagcuuac      780

guaguucaau uaccacuaua uggcguaaua gauacaccuu gcuggaaacu acauacaucu      840

ccauuaugua caacuaacac aaaagaagga ucuaacauau gccuaacacg cacagaucga      900

ggaugguacu gcgauaaugc agguuccgua ucauucuuuc cacaagcaga aacauguaaa      960

guaugcucaa acagaguauu cugugacacu augaacuccu uaacccuacc cucagaaguc     1020

aaucuaugca acguugacau auuuaaccca aaauacgacu guaaaaucau gacaucuaaa     1080

acagacguau caucaucagu uauuacaucc cuaggagcaa uaguaucuug cuacggaaaa     1140

acaaaaugua cagcauccaa caaaaacaaa ggaauaauca aaacauucuc aaacggcugc     1200

gacuacguau caaacaaagg uguagacaca guaucaguag gaaauacuuu auauuacgua     1260

aauaaacaag aaggacaauc ucuauacguu aaaggcgaac cuauuauaaa cuucuacgac     1320

ccacucguau ucccuucaga cgaauuugac gcaucuauau cccaaguuaa cgaaaaaauc     1380

aaccaaucau uagccuuuau aagaaaaucc gacgaauuau uacauaacgu caacgcugga     1440

aaaucaacaa cuaacauaau gauaaccaca auaauaauag ucaucauagu uauauuacua     1500

agucuaauag ccguaggccu ccuacuuuau ugcaaagcaa gaucaacacc aguaacauua     1560

uccaaagacc aacucagcgg cauaaacaau auagcuuuuu caaacuag                  1608


<210>  6072
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut6

<400>  6072
auggaacucc ucauccucaa agccaacgca aucacaacca uacuaacugc aguuacuuuc       60

ugcuucgcau ccggccaaaa caucaccgaa gaguucuacc aaucaaccug cuccgcaguc      120

uccaaaggau accucggagc ccuucgcacc ggcugguaca ccuccgucau aaccaucgaa      180

cucucaaaca uaaaagaaaa caaaugcaac ggcacagacg cgaaagucaa acuuaucaaa      240

caagaacucg acaaauacaa aaacgccguc accgaccugc agaugcucau gugcucaacc      300

cccgccacag gaagcggcuc ugcuaucgcu uccggcgucg ccgucugcaa aguccuccac      360

cucgaaggcg aaguaaacaa aaucaaguca gcccuccucu ccaccaacaa agccgucguc      420

ucucucucaa acggcguauc cguccucaca uucaaagucc ucgaccucaa aaacuacauc      480

gacaaacaac uucuccccau ccuaaacaaa caaucaugcu ccauccccaa ccccgaaaca      540

gucauggaau uucaacaaaa gaacaaccgc cucuuagaaa ucacccgaga auuuuccguc      600

aacgcgggag ucacaacccc cguuucuacg uauaugcuca ccaacuccga acuccuuucc      660

cucauaaacg acaugccaau caccaacgac caaaagaaac ucaugucaaa caacguccaa      720

aucguccgac aacaauccua cucuauuaug ugcaucauca aagaagaagu ucucgccuac      780

gucguccaac uaccccucua cggcgugauc gacacccccu gcuggaaacu acacaccuca      840

ccccucugca ccaccaacac caaggaaggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc uggcuccguc ucauucuucc cgcaagccga aacuugcaaa      960

guaugcucca acagaguauu cugcgacacc augaacucac uaacccuccc uuccgaaguc     1020

aaccuuugca acguugacau auucaaccca aaguacgauu gcaaaauuau gacauccaaa     1080

acagaugucu ccuccuccgu caucacaucc cucggugcca uuguaucaug cuacggaaaa     1140

accaaaugca ccgcauccaa caaaaacaaa ggaaucauca aaaccuucuc aaacggcugc     1200

gauuacgucu caaacaaagg agucgacaca gucuccgucg gaaacacccu auacuacguc     1260

aacaaacaag aaggccaauc ccuguacguc aaaggagaac ccaucaucaa cuucuacgac     1320

ccccucgucu ucccgagcga cgaguucgac gccuccaucu cacaagucaa ugaaaagauc     1380

aaccaauccc uugccuucau ccggaaaucg gacgaacucc uacacaacgu gaacgcugga     1440

aaaucaacca ccaacaucau gaucacaacc aucauuaucg ucaucaucgu cauacuccuc     1500

ucccuaaucg ccgucggccu ccuccuguau ugcaaagcuc gcuccacccc cgucacccug     1560

uccaaagacc aacucuccgg aaucaacaac aucgccuucu caaacuaa                  1608


<210>  6073
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6073
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6074
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6074
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

ccacccccgu gacccugagc aaggaccagc uguccggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6075
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6075
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6076
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6076
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

caacaccugu gaccuugagu aaggaucagc ugucugggau uaacaauauc gcuuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6077
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6077
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6078
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6078
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgca     1620

gcacaccggu gacccugucu aaggaucagc uuuccggaau uaacaauauc gcguucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6079
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6079
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau      120

uaacagcagu aacauucugu uuugccuccg gacaaaacau aacagaagaa uuuuaucaau      180

caacaugcuc ugcaguaucc aaagguuacu uaggcgcacu acgcacugga ugguauacau      240

caguaauaac aauagaacua ucaaacauaa aagaaaauaa auguaacggu acugacgcaa      300

aagugaaacu aauuaaacaa gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa      360

ugcuaaugug cucaacaccc gcaaccggau caggaucagc cauagccucc ggagucgcag      420

uaugcaaagu auuacaucuu gaaggagaag uaaauaaaau aaaaucagca uuacuaucca      480

caaauaaagc cguaguauca cuaucaaacg guguauccgu ccuuacauuc aaaguauuag      540

aucuaaaaaa cuacauagau aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa      600

uucccaaccc agaaacaguc auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa      660

cacgagaauu uucaguaaac gcaggaguaa ccacaccagu aaguacauac augcucacca      720

acucagaauu auuaucacuu auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa      780

ugucaaacaa uguccaaauu guuagacaac aaucauacuc uauaaugugu auaauaaaag      840

aagaaguacu agcuuacgua guucaauuac cacuauaugg cguaauagau acaccuugcu      900

ggaaacuaca uacaucucca uuauguacaa cuaacacaaa agaaggaucu aacauaugcc      960

uaacacgcac agaucgagga ugguacugcg auaaugcagg uuccguauca uucuuuccac     1020

aagcagaaac auguaaagua ugcucaaaca gaguauucug ugacacuaug aacuccuuaa     1080

cccuacccuc agaagucaau cuaugcaacg uugacauauu uaacccaaaa uacgacugua     1140

aaaucaugac aucuaaaaca gacguaucau caucaguuau uacaucccua ggagcaauag     1200

uaucuugcua cggaaaaaca aaauguacag cauccaacaa aaacaaagga auaaucaaaa     1260

cauucucaaa cggcugcgac uacguaucaa acaaaggugu agacacagua ucaguaggaa     1320

auacuuuaua uuacguaaau aaacaagaag gacaaucucu auacguuaaa ggcgaaccua     1380

uuauaaacuu cuacgaccca cucguauucc cuucagacga auuugacgca ucuauauccc     1440

aaguuaacga aaaaaucaac caaucauuag ccuuuauaag aaaauccgac gaauuauuac     1500

auaacgucaa cgcuggaaaa ucaacaacua acauaaugau aaccacaaua auaauaguca     1560

ucauaguuau auuacuaagu cuaauagccg uaggccuccu acuuuauugc aaagcaagau     1620

caacaccagu aacauuaucc aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa     1680

acuagggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6080
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6080
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgcaauc acaaccauac      120

uaacugcagu uacuuucugc uucgcauccg gccaaaacau caccgaagag uucuaccaau      180

caaccugcuc cgcagucucc aaaggauacc ucggagcccu ucgcaccggc ugguacaccu      240

ccgucauaac caucgaacuc ucaaacauaa aagaaaacaa augcaacggc acagacgcga      300

aagucaaacu uaucaaacaa gaacucgaca aauacaaaaa cgccgucacc gaccugcaga      360

ugcucaugug cucaaccccc gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caagucagcc cuccucucca      480

ccaacaaagc cgucgucucu cucucaaacg gcguauccgu ccucacauuc aaaguccucg      540

accucaaaaa cuacaucgac aaacaacuuc uccccauccu aaacaaacaa ucaugcucca      600

uccccaaccc cgaaacaguc auggaauuuc aacaaaagaa caaccgccuc uuagaaauca      660

cccgagaauu uuccgucaac gcgggaguca caacccccgu uucuacguau augcucacca      720

acuccgaacu ccuuucccuc auaaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguccaaauc guccgacaac aauccuacuc uauuaugugc aucaucaaag      840

aagaaguucu cgccuacguc guccaacuac cccucuacgg cgugaucgac acccccugcu      900

ggaaacuaca caccucaccc cucugcacca ccaacaccaa ggaaggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgcugg cuccgucuca uucuucccgc     1020

aagccgaaac uugcaaagua ugcuccaaca gaguauucug cgacaccaug aacucacuaa     1080

cccucccuuc cgaagucaac cuuugcaacg uugacauauu caacccaaag uacgauugca     1140

aaauuaugac auccaaaaca gaugucuccu ccuccgucau cacaucccuc ggugccauug     1200

uaucaugcua cggaaaaacc aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa     1260

ccuucucaaa cggcugcgau uacgucucaa acaaaggagu cgacacaguc uccgucggaa     1320

acacccuaua cuacgucaac aaacaagaag gccaaucccu guacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc cgagcgacga guucgacgcc uccaucucac     1440

aagucaauga aaagaucaac caaucccuug ccuucauccg gaaaucggac gaacuccuac     1500

acaacgugaa cgcuggaaaa ucaaccacca acaucaugau cacaaccauc auuaucguca     1560

ucaucgucau acuccucucc cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu     1620

ccacccccgu cacccugucc aaagaccaac ucuccggaau caacaacauc gccuucucaa     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6081
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6081
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6082
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6082
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcuc cacccccgug acccugagca aggaccagcu guccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6083
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6083
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6084
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6084
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacgguc aacaccugug accuugagua aggaucagcu gucugggauu     1680

aacaauaucg cuuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6085
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6085
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6086
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6086
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcag cacaccggug acccugucua aggaucagcu uuccggaauu     1680

aacaauaucg cguucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6087
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6087
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau cuuaaaagca      120

aaugcuauaa ccacaauauu aacagcagua acauucuguu uugccuccgg acaaaacaua      180

acagaagaau uuuaucaauc aacaugcucu gcaguaucca aagguuacuu aggcgcacua      240

cgcacuggau gguauacauc aguaauaaca auagaacuau caaacauaaa agaaaauaaa      300

uguaacggua cugacgcaaa agugaaacua auuaaacaag aacucgacaa auacaaaaau      360

gcuguaacag accuacaaau gcuaaugugc ucaacacccg caaccggauc aggaucagcc      420

auagccuccg gagucgcagu augcaaagua uuacaucuug aaggagaagu aaauaaaaua      480

aaaucagcau uacuauccac aaauaaagcc guaguaucac uaucaaacgg uguauccguc      540

cuuacauuca aaguauuaga ucuaaaaaac uacauagaua aacaacuacu acccaucuua      600

aacaaacaau caugcucaau ucccaaccca gaaacaguca uggaauuuca acaaaaaaac      660

aacagacucu uagaaauaac acgagaauuu ucaguaaacg caggaguaac cacaccagua      720

aguacauaca ugcucaccaa cucagaauua uuaucacuua uuaacgacau gccaauuaca      780

aacgaccaaa aaaaauuaau gucaaacaau guccaaauug uuagacaaca aucauacucu      840

auaaugugua uaauaaaaga agaaguacua gcuuacguag uucaauuacc acuauauggc      900

guaauagaua caccuugcug gaaacuacau acaucuccau uauguacaac uaacacaaaa      960

gaaggaucua acauaugccu aacacgcaca gaucgaggau gguacugcga uaaugcaggu     1020

uccguaucau ucuuuccaca agcagaaaca uguaaaguau gcucaaacag aguauucugu     1080

gacacuauga acuccuuaac ccuacccuca gaagucaauc uaugcaacgu ugacauauuu     1140

aacccaaaau acgacuguaa aaucaugaca ucuaaaacag acguaucauc aucaguuauu     1200

acaucccuag gagcaauagu aucuugcuac ggaaaaacaa aauguacagc auccaacaaa     1260

aacaaaggaa uaaucaaaac auucucaaac ggcugcgacu acguaucaaa caaaggugua     1320

gacacaguau caguaggaaa uacuuuauau uacguaaaua aacaagaagg acaaucucua     1380

uacguuaaag gcgaaccuau uauaaacuuc uacgacccac ucguauuccc uucagacgaa     1440

uuugacgcau cuauauccca aguuaacgaa aaaaucaacc aaucauuagc cuuuauaaga     1500

aaauccgacg aauuauuaca uaacgucaac gcuggaaaau caacaacuaa cauaaugaua     1560

accacaauaa uaauagucau cauaguuaua uuacuaaguc uaauagccgu aggccuccua     1620

cuuuauugca aagcaagauc aacaccagua acauuaucca aagaccaacu cagcggcaua     1680

aacaauauag cuuuuucaaa cuagggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6088
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6088
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgcaauca caaccauacu aacugcaguu acuuucugcu ucgcauccgg ccaaaacauc      180

accgaagagu ucuaccaauc aaccugcucc gcagucucca aaggauaccu cggagcccuu      240

cgcaccggcu gguacaccuc cgucauaacc aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca cagacgcgaa agucaaacuu aucaaacaag aacucgacaa auacaaaaac      360

gccgucaccg accugcagau gcucaugugc ucaacccccg ccacaggaag cggcucugcu      420

aucgcuuccg gcgucgccgu cugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aagucagccc uccucuccac caacaaagcc gucgucucuc ucucaaacgg cguauccguc      540

cucacauuca aaguccucga ccucaaaaac uacaucgaca aacaacuucu ccccauccua      600

aacaaacaau caugcuccau ccccaacccc gaaacaguca uggaauuuca acaaaagaac      660

aaccgccucu uagaaaucac ccgagaauuu uccgucaacg cgggagucac aacccccguu      720

ucuacguaua ugcucaccaa cuccgaacuc cuuucccuca uaaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guccaaaucg uccgacaaca auccuacucu      840

auuaugugca ucaucaaaga agaaguucuc gccuacgucg uccaacuacc ccucuacggc      900

gugaucgaca cccccugcug gaaacuacac accucacccc ucugcaccac caacaccaag      960

gaaggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgcuggc     1020

uccgucucau ucuucccgca agccgaaacu ugcaaaguau gcuccaacag aguauucugc     1080

gacaccauga acucacuaac ccucccuucc gaagucaacc uuugcaacgu ugacauauuc     1140

aacccaaagu acgauugcaa aauuaugaca uccaaaacag augucuccuc cuccgucauc     1200

acaucccucg gugccauugu aucaugcuac ggaaaaacca aaugcaccgc auccaacaaa     1260

aacaaaggaa ucaucaaaac cuucucaaac ggcugcgauu acgucucaaa caaaggaguc     1320

gacacagucu ccgucggaaa cacccuauac uacgucaaca aacaagaagg ccaaucccug     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc ucgucuuccc gagcgacgag     1440

uucgacgccu ccaucucaca agucaaugaa aagaucaacc aaucccuugc cuucauccgg     1500

aaaucggacg aacuccuaca caacgugaac gcuggaaaau caaccaccaa caucaugauc     1560

acaaccauca uuaucgucau caucgucaua cuccucuccc uaaucgccgu cggccuccuc     1620

cuguauugca aagcucgcuc cacccccguc acccugucca aagaccaacu cuccggaauc     1680

aacaacaucg ccuucucaaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6089
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6089
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6090
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6090
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcucca cccccgugac ccugagcaag     1740

gaccagcugu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6091
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6091
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6092
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6092
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggucaa caccugugac cuugaguaag     1740

gaucagcugu cugggauuaa caauaucgcu uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6093
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6093
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6094
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6094
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcagca caccggugac ccugucuaag     1740

gaucagcuuu ccggaauuaa caauaucgcg uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6095
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6095
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaaucu uaaaagcaaa ugcuauaacc acaauauuaa cagcaguaac auucuguuuu      240

gccuccggac aaaacauaac agaagaauuu uaucaaucaa caugcucugc aguauccaaa      300

gguuacuuag gcgcacuacg cacuggaugg uauacaucag uaauaacaau agaacuauca      360

aacauaaaag aaaauaaaug uaacgguacu gacgcaaaag ugaaacuaau uaaacaagaa      420

cucgacaaau acaaaaaugc uguaacagac cuacaaaugc uaaugugcuc aacacccgca      480

accggaucag gaucagccau agccuccgga gucgcaguau gcaaaguauu acaucuugaa      540

ggagaaguaa auaaaauaaa aucagcauua cuauccacaa auaaagccgu aguaucacua      600

ucaaacggug uauccguccu uacauucaaa guauuagauc uaaaaaacua cauagauaaa      660

caacuacuac ccaucuuaaa caaacaauca ugcucaauuc ccaacccaga aacagucaug      720

gaauuucaac aaaaaaacaa cagacucuua gaaauaacac gagaauuuuc aguaaacgca      780

ggaguaacca caccaguaag uacauacaug cucaccaacu cagaauuauu aucacuuauu      840

aacgacaugc caauuacaaa cgaccaaaaa aaauuaaugu caaacaaugu ccaaauuguu      900

agacaacaau cauacucuau aauguguaua auaaaagaag aaguacuagc uuacguaguu      960

caauuaccac uauauggcgu aauagauaca ccuugcugga aacuacauac aucuccauua     1020

uguacaacua acacaaaaga aggaucuaac auaugccuaa cacgcacaga ucgaggaugg     1080

uacugcgaua augcagguuc cguaucauuc uuuccacaag cagaaacaug uaaaguaugc     1140

ucaaacagag uauucuguga cacuaugaac uccuuaaccc uacccucaga agucaaucua     1200

ugcaacguug acauauuuaa cccaaaauac gacuguaaaa ucaugacauc uaaaacagac     1260

guaucaucau caguuauuac aucccuagga gcaauaguau cuugcuacgg aaaaacaaaa     1320

uguacagcau ccaacaaaaa caaaggaaua aucaaaacau ucucaaacgg cugcgacuac     1380

guaucaaaca aagguguaga cacaguauca guaggaaaua cuuuauauua cguaaauaaa     1440

caagaaggac aaucucuaua cguuaaaggc gaaccuauua uaaacuucua cgacccacuc     1500

guauucccuu cagacgaauu ugacgcaucu auaucccaag uuaacgaaaa aaucaaccaa     1560

ucauuagccu uuauaagaaa auccgacgaa uuauuacaua acgucaacgc uggaaaauca     1620

acaacuaaca uaaugauaac cacaauaaua auagucauca uaguuauauu acuaagucua     1680

auagccguag gccuccuacu uuauugcaaa gcaagaucaa caccaguaac auuauccaaa     1740

gaccaacuca gcggcauaaa caauauagcu uuuucaaacu agggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6096
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6096
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgcaaucaca accauacuaa cugcaguuac uuucugcuuc      240

gcauccggcc aaaacaucac cgaagaguuc uaccaaucaa ccugcuccgc agucuccaaa      300

ggauaccucg gagcccuucg caccggcugg uacaccuccg ucauaaccau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcaca gacgcgaaag ucaaacuuau caaacaagaa      420

cucgacaaau acaaaaacgc cgucaccgac cugcagaugc ucaugugcuc aacccccgcc      480

acaggaagcg gcucugcuau cgcuuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa gucagcccuc cucuccacca acaaagccgu cgucucucuc      600

ucaaacggcg uauccguccu cacauucaaa guccucgacc ucaaaaacua caucgacaaa      660

caacuucucc ccauccuaaa caaacaauca ugcuccaucc ccaaccccga aacagucaug      720

gaauuucaac aaaagaacaa ccgccucuua gaaaucaccc gagaauuuuc cgucaacgcg      780

ggagucacaa cccccguuuc uacguauaug cucaccaacu ccgaacuccu uucccucaua      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu ccaaaucguc      900

cgacaacaau ccuacucuau uaugugcauc aucaaagaag aaguucucgc cuacgucguc      960

caacuacccc ucuacggcgu gaucgacacc cccugcugga aacuacacac cucaccccuc     1020

ugcaccacca acaccaagga aggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgcuggcuc cgucucauuc uucccgcaag ccgaaacuug caaaguaugc     1140

uccaacagag uauucugcga caccaugaac ucacuaaccc ucccuuccga agucaaccuu     1200

ugcaacguug acauauucaa cccaaaguac gauugcaaaa uuaugacauc caaaacagau     1260

gucuccuccu ccgucaucac aucccucggu gccauuguau caugcuacgg aaaaaccaaa     1320

ugcaccgcau ccaacaaaaa caaaggaauc aucaaaaccu ucucaaacgg cugcgauuac     1380

gucucaaaca aaggagucga cacagucucc gucggaaaca cccuauacua cgucaacaaa     1440

caagaaggcc aaucccugua cgucaaagga gaacccauca ucaacuucua cgacccccuc     1500

gucuucccga gcgacgaguu cgacgccucc aucucacaag ucaaugaaaa gaucaaccaa     1560

ucccuugccu ucauccggaa aucggacgaa cuccuacaca acgugaacgc uggaaaauca     1620

accaccaaca ucaugaucac aaccaucauu aucgucauca ucgucauacu ccucucccua     1680

aucgccgucg gccuccuccu guauugcaaa gcucgcucca cccccgucac ccuguccaaa     1740

gaccaacucu ccggaaucaa caacaucgcc uucucaaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6097
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6097
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6098
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6098
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcuccac ccccgugacc     1680

cugagcaagg accagcuguc cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6099
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6099
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6100
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6100
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggucaac accugugacc     1680

uugaguaagg aucagcuguc ugggauuaac aauaucgcuu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6101
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6101
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6102
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6102
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcagcac accggugacc     1680

cugucuaagg aucagcuuuc cggaauuaac aauaucgcgu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6103
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6103
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaaucuu aaaagcaaau gcuauaacca caauauuaac agcaguaaca      180

uucuguuuug ccuccggaca aaacauaaca gaagaauuuu aucaaucaac augcucugca      240

guauccaaag guuacuuagg cgcacuacgc acuggauggu auacaucagu aauaacaaua      300

gaacuaucaa acauaaaaga aaauaaaugu aacgguacug acgcaaaagu gaaacuaauu      360

aaacaagaac ucgacaaaua caaaaaugcu guaacagacc uacaaaugcu aaugugcuca      420

acacccgcaa ccggaucagg aucagccaua gccuccggag ucgcaguaug caaaguauua      480

caucuugaag gagaaguaaa uaaaauaaaa ucagcauuac uauccacaaa uaaagccgua      540

guaucacuau caaacggugu auccguccuu acauucaaag uauuagaucu aaaaaacuac      600

auagauaaac aacuacuacc caucuuaaac aaacaaucau gcucaauucc caacccagaa      660

acagucaugg aauuucaaca aaaaaacaac agacucuuag aaauaacacg agaauuuuca      720

guaaacgcag gaguaaccac accaguaagu acauacaugc ucaccaacuc agaauuauua      780

ucacuuauua acgacaugcc aauuacaaac gaccaaaaaa aauuaauguc aaacaauguc      840

caaauuguua gacaacaauc auacucuaua auguguauaa uaaaagaaga aguacuagcu      900

uacguaguuc aauuaccacu auauggcgua auagauacac cuugcuggaa acuacauaca      960

ucuccauuau guacaacuaa cacaaaagaa ggaucuaaca uaugccuaac acgcacagau     1020

cgaggauggu acugcgauaa ugcagguucc guaucauucu uuccacaagc agaaacaugu     1080

aaaguaugcu caaacagagu auucugugac acuaugaacu ccuuaacccu acccucagaa     1140

gucaaucuau gcaacguuga cauauuuaac ccaaaauacg acuguaaaau caugacaucu     1200

aaaacagacg uaucaucauc aguuauuaca ucccuaggag caauaguauc uugcuacgga     1260

aaaacaaaau guacagcauc caacaaaaac aaaggaauaa ucaaaacauu cucaaacggc     1320

ugcgacuacg uaucaaacaa agguguagac acaguaucag uaggaaauac uuuauauuac     1380

guaaauaaac aagaaggaca aucucuauac guuaaaggcg aaccuauuau aaacuucuac     1440

gacccacucg uauucccuuc agacgaauuu gacgcaucua uaucccaagu uaacgaaaaa     1500

aucaaccaau cauuagccuu uauaagaaaa uccgacgaau uauuacauaa cgucaacgcu     1560

ggaaaaucaa caacuaacau aaugauaacc acaauaauaa uagucaucau aguuauauua     1620

cuaagucuaa uagccguagg ccuccuacuu uauugcaaag caagaucaac accaguaaca     1680

uuauccaaag accaacucag cggcauaaac aauauagcuu uuucaaacua gggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6104
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6104
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gcaaucacaa ccauacuaac ugcaguuacu      180

uucugcuucg cauccggcca aaacaucacc gaagaguucu accaaucaac cugcuccgca      240

gucuccaaag gauaccucgg agcccuucgc accggcuggu acaccuccgu cauaaccauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcacag acgcgaaagu caaacuuauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucaccgacc ugcagaugcu caugugcuca      420

acccccgcca caggaagcgg cucugcuauc gcuuccggcg ucgccgucug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaag ucagcccucc ucuccaccaa caaagccguc      540

gucucucucu caaacggcgu auccguccuc acauucaaag uccucgaccu caaaaacuac      600

aucgacaaac aacuucuccc cauccuaaac aaacaaucau gcuccauccc caaccccgaa      660

acagucaugg aauuucaaca aaagaacaac cgccucuuag aaaucacccg agaauuuucc      720

gucaacgcgg gagucacaac ccccguuucu acguauaugc ucaccaacuc cgaacuccuu      780

ucccucauaa acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacguc      840

caaaucgucc gacaacaauc cuacucuauu augugcauca ucaaagaaga aguucucgcc      900

uacgucgucc aacuaccccu cuacggcgug aucgacaccc ccugcuggaa acuacacacc      960

ucaccccucu gcaccaccaa caccaaggaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgcuggcucc gucucauucu ucccgcaagc cgaaacuugc     1080

aaaguaugcu ccaacagagu auucugcgac accaugaacu cacuaacccu cccuuccgaa     1140

gucaaccuuu gcaacguuga cauauucaac ccaaaguacg auugcaaaau uaugacaucc     1200

aaaacagaug ucuccuccuc cgucaucaca ucccucggug ccauuguauc augcuacgga     1260

aaaaccaaau gcaccgcauc caacaaaaac aaaggaauca ucaaaaccuu cucaaacggc     1320

ugcgauuacg ucucaaacaa aggagucgac acagucuccg ucggaaacac ccuauacuac     1380

gucaacaaac aagaaggcca aucccuguac gucaaaggag aacccaucau caacuucuac     1440

gacccccucg ucuucccgag cgacgaguuc gacgccucca ucucacaagu caaugaaaag     1500

aucaaccaau cccuugccuu cauccggaaa ucggacgaac uccuacacaa cgugaacgcu     1560

ggaaaaucaa ccaccaacau caugaucaca accaucauua ucgucaucau cgucauacuc     1620

cucucccuaa ucgccgucgg ccuccuccug uauugcaaag cucgcuccac ccccgucacc     1680

cuguccaaag accaacucuc cggaaucaac aacaucgccu ucucaaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6105
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6105
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6106
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6106
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cuccaccccc     1620

gugacccuga gcaaggacca gcuguccggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6107
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6107
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6108
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6108
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gucaacaccu     1620

gugaccuuga guaaggauca gcugucuggg auuaacaaua ucgcuuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6109
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6109
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6110
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6110
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cagcacaccg     1620

gugacccugu cuaaggauca gcuuuccgga auuaacaaua ucgcguucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6111
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6111
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aaucuuaaaa gcaaaugcua uaaccacaau auuaacagca      120

guaacauucu guuuugccuc cggacaaaac auaacagaag aauuuuauca aucaacaugc      180

ucugcaguau ccaaagguua cuuaggcgca cuacgcacug gaugguauac aucaguaaua      240

acaauagaac uaucaaacau aaaagaaaau aaauguaacg guacugacgc aaaagugaaa      300

cuaauuaaac aagaacucga caaauacaaa aaugcuguaa cagaccuaca aaugcuaaug      360

ugcucaacac ccgcaaccgg aucaggauca gccauagccu ccggagucgc aguaugcaaa      420

guauuacauc uugaaggaga aguaaauaaa auaaaaucag cauuacuauc cacaaauaaa      480

gccguaguau cacuaucaaa cgguguaucc guccuuacau ucaaaguauu agaucuaaaa      540

aacuacauag auaaacaacu acuacccauc uuaaacaaac aaucaugcuc aauucccaac      600

ccagaaacag ucauggaauu ucaacaaaaa aacaacagac ucuuagaaau aacacgagaa      660

uuuucaguaa acgcaggagu aaccacacca guaaguacau acaugcucac caacucagaa      720

uuauuaucac uuauuaacga caugccaauu acaaacgacc aaaaaaaauu aaugucaaac      780

aauguccaaa uuguuagaca acaaucauac ucuauaaugu guauaauaaa agaagaagua      840

cuagcuuacg uaguucaauu accacuauau ggcguaauag auacaccuug cuggaaacua      900

cauacaucuc cauuauguac aacuaacaca aaagaaggau cuaacauaug ccuaacacgc      960

acagaucgag gaugguacug cgauaaugca gguuccguau cauucuuucc acaagcagaa     1020

acauguaaag uaugcucaaa cagaguauuc ugugacacua ugaacuccuu aacccuaccc     1080

ucagaaguca aucuaugcaa cguugacaua uuuaacccaa aauacgacug uaaaaucaug     1140

acaucuaaaa cagacguauc aucaucaguu auuacauccc uaggagcaau aguaucuugc     1200

uacggaaaaa caaaauguac agcauccaac aaaaacaaag gaauaaucaa aacauucuca     1260

aacggcugcg acuacguauc aaacaaaggu guagacacag uaucaguagg aaauacuuua     1320

uauuacguaa auaaacaaga aggacaaucu cuauacguua aaggcgaacc uauuauaaac     1380

uucuacgacc cacucguauu cccuucagac gaauuugacg caucuauauc ccaaguuaac     1440

gaaaaaauca accaaucauu agccuuuaua agaaaauccg acgaauuauu acauaacguc     1500

aacgcuggaa aaucaacaac uaacauaaug auaaccacaa uaauaauagu caucauaguu     1560

auauuacuaa gucuaauagc cguaggccuc cuacuuuauu gcaaagcaag aucaacacca     1620

guaacauuau ccaaagacca acucagcggc auaaacaaua uagcuuuuuc aaacuaggga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6112
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6112
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcaa ucacaaccau acuaacugca      120

guuacuuucu gcuucgcauc cggccaaaac aucaccgaag aguucuacca aucaaccugc      180

uccgcagucu ccaaaggaua ccucggagcc cuucgcaccg gcugguacac cuccgucaua      240

accaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcacagacgc gaaagucaaa      300

cuuaucaaac aagaacucga caaauacaaa aacgccguca ccgaccugca gaugcucaug      360

ugcucaaccc ccgccacagg aagcggcucu gcuaucgcuu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaagucag cccuccucuc caccaacaaa      480

gccgucgucu cucucucaaa cggcguaucc guccucacau ucaaaguccu cgaccucaaa      540

aacuacaucg acaaacaacu ucuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

cccgaaacag ucauggaauu ucaacaaaag aacaaccgcc ucuuagaaau cacccgagaa      660

uuuuccguca acgcgggagu cacaaccccc guuucuacgu auaugcucac caacuccgaa      720

cuccuuuccc ucauaaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguccaaa ucguccgaca acaauccuac ucuauuaugu gcaucaucaa agaagaaguu      840

cucgccuacg ucguccaacu accccucuac ggcgugaucg acacccccug cuggaaacua      900

cacaccucac cccucugcac caccaacacc aaggaaggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcu ggcuccgucu cauucuuccc gcaagccgaa     1020

acuugcaaag uaugcuccaa cagaguauuc ugcgacacca ugaacucacu aacccucccu     1080

uccgaaguca accuuugcaa cguugacaua uucaacccaa aguacgauug caaaauuaug     1140

acauccaaaa cagaugucuc cuccuccguc aucacauccc ucggugccau uguaucaugc     1200

uacggaaaaa ccaaaugcac cgcauccaac aaaaacaaag gaaucaucaa aaccuucuca     1260

aacggcugcg auuacgucuc aaacaaagga gucgacacag ucuccgucgg aaacacccua     1320

uacuacguca acaaacaaga aggccaaucc cuguacguca aaggagaacc caucaucaac     1380

uucuacgacc cccucgucuu cccgagcgac gaguucgacg ccuccaucuc acaagucaau     1440

gaaaagauca accaaucccu ugccuucauc cggaaaucgg acgaacuccu acacaacgug     1500

aacgcuggaa aaucaaccac caacaucaug aucacaacca ucauuaucgu caucaucguc     1560

auacuccucu cccuaaucgc cgucggccuc cuccuguauu gcaaagcucg cuccaccccc     1620

gucacccugu ccaaagacca acucuccgga aucaacaaca ucgccuucuc aaacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6113
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6113
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1800

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6114
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6114
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      540

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      600

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      660

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      720

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc     1140

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1200

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1260

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1740

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu ccacccccgu gacccugagc     1800

aaggaccagc uguccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6115
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6115
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      780

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1800

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6116
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6116
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      540

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      600

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      660

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      720

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      780

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      840

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      900

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      960

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua     1020

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu     1080

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg     1140

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1200

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1260

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1320

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1380

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1440

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1500

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1560

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1620

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1680

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1740

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu caacaccugu gaccuugagu     1800

aaggaucagc ugucugggau uaacaauauc gcuuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6117
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6117
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      780

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1800

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6118
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6118
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      540

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      600

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      660

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      720

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      780

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      840

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      900

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      960

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug     1020

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu     1080

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc     1140

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1200

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1260

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1320

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1380

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1440

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1500

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1560

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1620

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1680

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1740

cuuaucgccg uggggcugcu ccuguacugc aaagcucgca gcacaccggu gacccugucu     1800

aaggaucagc uuuccggaau uaacaauauc gcguucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6119
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6119
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau uaacagcagu aacauucugu      300

uuugccuccg gacaaaacau aacagaagaa uuuuaucaau caacaugcuc ugcaguaucc      360

aaagguuacu uaggcgcacu acgcacugga ugguauacau caguaauaac aauagaacua      420

ucaaacauaa aagaaaauaa auguaacggu acugacgcaa aagugaaacu aauuaaacaa      480

gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa ugcuaaugug cucaacaccc      540

gcaaccggau caggaucagc cauagccucc ggagucgcag uaugcaaagu auuacaucuu      600

gaaggagaag uaaauaaaau aaaaucagca uuacuaucca caaauaaagc cguaguauca      660

cuaucaaacg guguauccgu ccuuacauuc aaaguauuag aucuaaaaaa cuacauagau      720

aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa uucccaaccc agaaacaguc      780

auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa cacgagaauu uucaguaaac      840

gcaggaguaa ccacaccagu aaguacauac augcucacca acucagaauu auuaucacuu      900

auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa ugucaaacaa uguccaaauu      960

guuagacaac aaucauacuc uauaaugugu auaauaaaag aagaaguacu agcuuacgua     1020

guucaauuac cacuauaugg cguaauagau acaccuugcu ggaaacuaca uacaucucca     1080

uuauguacaa cuaacacaaa agaaggaucu aacauaugcc uaacacgcac agaucgagga     1140

ugguacugcg auaaugcagg uuccguauca uucuuuccac aagcagaaac auguaaagua     1200

ugcucaaaca gaguauucug ugacacuaug aacuccuuaa cccuacccuc agaagucaau     1260

cuaugcaacg uugacauauu uaacccaaaa uacgacugua aaaucaugac aucuaaaaca     1320

gacguaucau caucaguuau uacaucccua ggagcaauag uaucuugcua cggaaaaaca     1380

aaauguacag cauccaacaa aaacaaagga auaaucaaaa cauucucaaa cggcugcgac     1440

uacguaucaa acaaaggugu agacacagua ucaguaggaa auacuuuaua uuacguaaau     1500

aaacaagaag gacaaucucu auacguuaaa ggcgaaccua uuauaaacuu cuacgaccca     1560

cucguauucc cuucagacga auuugacgca ucuauauccc aaguuaacga aaaaaucaac     1620

caaucauuag ccuuuauaag aaaauccgac gaauuauuac auaacgucaa cgcuggaaaa     1680

ucaacaacua acauaaugau aaccacaaua auaauaguca ucauaguuau auuacuaagu     1740

cuaauagccg uaggccuccu acuuuauugc aaagcaagau caacaccagu aacauuaucc     1800

aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa acuagggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6120
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6120
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccucaaagc caacgcaauc acaaccauac uaacugcagu uacuuucugc      300

uucgcauccg gccaaaacau caccgaagag uucuaccaau caaccugcuc cgcagucucc      360

aaaggauacc ucggagcccu ucgcaccggc ugguacaccu ccgucauaac caucgaacuc      420

ucaaacauaa aagaaaacaa augcaacggc acagacgcga aagucaaacu uaucaaacaa      480

gaacucgaca aauacaaaaa cgccgucacc gaccugcaga ugcucaugug cucaaccccc      540

gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg ucugcaaagu ccuccaccuc      600

gaaggcgaag uaaacaaaau caagucagcc cuccucucca ccaacaaagc cgucgucucu      660

cucucaaacg gcguauccgu ccucacauuc aaaguccucg accucaaaaa cuacaucgac      720

aaacaacuuc uccccauccu aaacaaacaa ucaugcucca uccccaaccc cgaaacaguc      780

auggaauuuc aacaaaagaa caaccgccuc uuagaaauca cccgagaauu uuccgucaac      840

gcgggaguca caacccccgu uucuacguau augcucacca acuccgaacu ccuuucccuc      900

auaaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      960

guccgacaac aauccuacuc uauuaugugc aucaucaaag aagaaguucu cgccuacguc     1020

guccaacuac cccucuacgg cgugaucgac acccccugcu ggaaacuaca caccucaccc     1080

cucugcacca ccaacaccaa ggaaggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgcugg cuccgucuca uucuucccgc aagccgaaac uugcaaagua     1200

ugcuccaaca gaguauucug cgacaccaug aacucacuaa cccucccuuc cgaagucaac     1260

cuuugcaacg uugacauauu caacccaaag uacgauugca aaauuaugac auccaaaaca     1320

gaugucuccu ccuccgucau cacaucccuc ggugccauug uaucaugcua cggaaaaacc     1380

aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa ccuucucaaa cggcugcgau     1440

uacgucucaa acaaaggagu cgacacaguc uccgucggaa acacccuaua cuacgucaac     1500

aaacaagaag gccaaucccu guacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1560

cucgucuucc cgagcgacga guucgacgcc uccaucucac aagucaauga aaagaucaac     1620

caaucccuug ccuucauccg gaaaucggac gaacuccuac acaacgugaa cgcuggaaaa     1680

ucaaccacca acaucaugau cacaaccauc auuaucguca ucaucgucau acuccucucc     1740

cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu ccacccccgu cacccugucc     1800

aaagaccaac ucuccggaau caacaacauc gccuucucaa acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6121
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6121
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6122
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6122
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      480

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc      960

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu ccacccccgu gacccugagc     1620

aaggaccagc uguccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6123
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6123
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6124
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6124
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      360

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      420

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      480

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      540

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      660

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      720

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      780

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua      840

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu      900

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg      960

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1020

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1080

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1200

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1260

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1320

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1380

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1440

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1500

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1560

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu caacaccugu gaccuugagu     1620

aaggaucagc ugucugggau uaacaauauc gcuuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6125
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6125
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6126
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6126
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      360

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      420

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      480

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      540

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      660

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      720

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug      840

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu      900

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc      960

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1020

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1080

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1200

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1260

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1380

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1440

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1500

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1560

cuuaucgccg uggggcugcu ccuguacugc aaagcucgca gcacaccggu gacccugucu     1620

aaggaucagc uuuccggaau uaacaauauc gcguucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6127
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6127
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau uaacagcagu aacauucugu      120

uuugccuccg gacaaaacau aacagaagaa uuuuaucaau caacaugcuc ugcaguaucc      180

aaagguuacu uaggcgcacu acgcacugga ugguauacau caguaauaac aauagaacua      240

ucaaacauaa aagaaaauaa auguaacggu acugacgcaa aagugaaacu aauuaaacaa      300

gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa ugcuaaugug cucaacaccc      360

gcaaccggau caggaucagc cauagccucc ggagucgcag uaugcaaagu auuacaucuu      420

gaaggagaag uaaauaaaau aaaaucagca uuacuaucca caaauaaagc cguaguauca      480

cuaucaaacg guguauccgu ccuuacauuc aaaguauuag aucuaaaaaa cuacauagau      540

aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa uucccaaccc agaaacaguc      600

auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa cacgagaauu uucaguaaac      660

gcaggaguaa ccacaccagu aaguacauac augcucacca acucagaauu auuaucacuu      720

auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa ugucaaacaa uguccaaauu      780

guuagacaac aaucauacuc uauaaugugu auaauaaaag aagaaguacu agcuuacgua      840

guucaauuac cacuauaugg cguaauagau acaccuugcu ggaaacuaca uacaucucca      900

uuauguacaa cuaacacaaa agaaggaucu aacauaugcc uaacacgcac agaucgagga      960

ugguacugcg auaaugcagg uuccguauca uucuuuccac aagcagaaac auguaaagua     1020

ugcucaaaca gaguauucug ugacacuaug aacuccuuaa cccuacccuc agaagucaau     1080

cuaugcaacg uugacauauu uaacccaaaa uacgacugua aaaucaugac aucuaaaaca     1140

gacguaucau caucaguuau uacaucccua ggagcaauag uaucuugcua cggaaaaaca     1200

aaauguacag cauccaacaa aaacaaagga auaaucaaaa cauucucaaa cggcugcgac     1260

uacguaucaa acaaaggugu agacacagua ucaguaggaa auacuuuaua uuacguaaau     1320

aaacaagaag gacaaucucu auacguuaaa ggcgaaccua uuauaaacuu cuacgaccca     1380

cucguauucc cuucagacga auuugacgca ucuauauccc aaguuaacga aaaaaucaac     1440

caaucauuag ccuuuauaag aaaauccgac gaauuauuac auaacgucaa cgcuggaaaa     1500

ucaacaacua acauaaugau aaccacaaua auaauaguca ucauaguuau auuacuaagu     1560

cuaauagccg uaggccuccu acuuuauugc aaagcaagau caacaccagu aacauuaucc     1620

aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa acuagggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6128
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6128
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgcaauc acaaccauac uaacugcagu uacuuucugc      120

uucgcauccg gccaaaacau caccgaagag uucuaccaau caaccugcuc cgcagucucc      180

aaaggauacc ucggagcccu ucgcaccggc ugguacaccu ccgucauaac caucgaacuc      240

ucaaacauaa aagaaaacaa augcaacggc acagacgcga aagucaaacu uaucaaacaa      300

gaacucgaca aauacaaaaa cgccgucacc gaccugcaga ugcucaugug cucaaccccc      360

gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg ucugcaaagu ccuccaccuc      420

gaaggcgaag uaaacaaaau caagucagcc cuccucucca ccaacaaagc cgucgucucu      480

cucucaaacg gcguauccgu ccucacauuc aaaguccucg accucaaaaa cuacaucgac      540

aaacaacuuc uccccauccu aaacaaacaa ucaugcucca uccccaaccc cgaaacaguc      600

auggaauuuc aacaaaagaa caaccgccuc uuagaaauca cccgagaauu uuccgucaac      660

gcgggaguca caacccccgu uucuacguau augcucacca acuccgaacu ccuuucccuc      720

auaaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      780

guccgacaac aauccuacuc uauuaugugc aucaucaaag aagaaguucu cgccuacguc      840

guccaacuac cccucuacgg cgugaucgac acccccugcu ggaaacuaca caccucaccc      900

cucugcacca ccaacaccaa ggaaggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgcugg cuccgucuca uucuucccgc aagccgaaac uugcaaagua     1020

ugcuccaaca gaguauucug cgacaccaug aacucacuaa cccucccuuc cgaagucaac     1080

cuuugcaacg uugacauauu caacccaaag uacgauugca aaauuaugac auccaaaaca     1140

gaugucuccu ccuccgucau cacaucccuc ggugccauug uaucaugcua cggaaaaacc     1200

aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa ccuucucaaa cggcugcgau     1260

uacgucucaa acaaaggagu cgacacaguc uccgucggaa acacccuaua cuacgucaac     1320

aaacaagaag gccaaucccu guacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc cgagcgacga guucgacgcc uccaucucac aagucaauga aaagaucaac     1440

caaucccuug ccuucauccg gaaaucggac gaacuccuac acaacgugaa cgcuggaaaa     1500

ucaaccacca acaucaugau cacaaccauc auuaucguca ucaucgucau acuccucucc     1560

cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu ccacccccgu cacccugucc     1620

aaagaccaac ucuccggaau caacaacauc gccuucucaa acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6129
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6129
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6130
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6130
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

ccacccccgu gacccugagc aaggaccagc uguccggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6131
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6131
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6132
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6132
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

caacaccugu gaccuugagu aaggaucagc ugucugggau uaacaauauc gcuuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6133
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6133
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6134
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6134
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgca     1620

gcacaccggu gacccugucu aaggaucagc uuuccggaau uaacaauauc gcguucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6135
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6135
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau      120

uaacagcagu aacauucugu uuugccuccg gacaaaacau aacagaagaa uuuuaucaau      180

caacaugcuc ugcaguaucc aaagguuacu uaggcgcacu acgcacugga ugguauacau      240

caguaauaac aauagaacua ucaaacauaa aagaaaauaa auguaacggu acugacgcaa      300

aagugaaacu aauuaaacaa gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa      360

ugcuaaugug cucaacaccc gcaaccggau caggaucagc cauagccucc ggagucgcag      420

uaugcaaagu auuacaucuu gaaggagaag uaaauaaaau aaaaucagca uuacuaucca      480

caaauaaagc cguaguauca cuaucaaacg guguauccgu ccuuacauuc aaaguauuag      540

aucuaaaaaa cuacauagau aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa      600

uucccaaccc agaaacaguc auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa      660

cacgagaauu uucaguaaac gcaggaguaa ccacaccagu aaguacauac augcucacca      720

acucagaauu auuaucacuu auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa      780

ugucaaacaa uguccaaauu guuagacaac aaucauacuc uauaaugugu auaauaaaag      840

aagaaguacu agcuuacgua guucaauuac cacuauaugg cguaauagau acaccuugcu      900

ggaaacuaca uacaucucca uuauguacaa cuaacacaaa agaaggaucu aacauaugcc      960

uaacacgcac agaucgagga ugguacugcg auaaugcagg uuccguauca uucuuuccac     1020

aagcagaaac auguaaagua ugcucaaaca gaguauucug ugacacuaug aacuccuuaa     1080

cccuacccuc agaagucaau cuaugcaacg uugacauauu uaacccaaaa uacgacugua     1140

aaaucaugac aucuaaaaca gacguaucau caucaguuau uacaucccua ggagcaauag     1200

uaucuugcua cggaaaaaca aaauguacag cauccaacaa aaacaaagga auaaucaaaa     1260

cauucucaaa cggcugcgac uacguaucaa acaaaggugu agacacagua ucaguaggaa     1320

auacuuuaua uuacguaaau aaacaagaag gacaaucucu auacguuaaa ggcgaaccua     1380

uuauaaacuu cuacgaccca cucguauucc cuucagacga auuugacgca ucuauauccc     1440

aaguuaacga aaaaaucaac caaucauuag ccuuuauaag aaaauccgac gaauuauuac     1500

auaacgucaa cgcuggaaaa ucaacaacua acauaaugau aaccacaaua auaauaguca     1560

ucauaguuau auuacuaagu cuaauagccg uaggccuccu acuuuauugc aaagcaagau     1620

caacaccagu aacauuaucc aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa     1680

acuagggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6136
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6136
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgcaauc acaaccauac      120

uaacugcagu uacuuucugc uucgcauccg gccaaaacau caccgaagag uucuaccaau      180

caaccugcuc cgcagucucc aaaggauacc ucggagcccu ucgcaccggc ugguacaccu      240

ccgucauaac caucgaacuc ucaaacauaa aagaaaacaa augcaacggc acagacgcga      300

aagucaaacu uaucaaacaa gaacucgaca aauacaaaaa cgccgucacc gaccugcaga      360

ugcucaugug cucaaccccc gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caagucagcc cuccucucca      480

ccaacaaagc cgucgucucu cucucaaacg gcguauccgu ccucacauuc aaaguccucg      540

accucaaaaa cuacaucgac aaacaacuuc uccccauccu aaacaaacaa ucaugcucca      600

uccccaaccc cgaaacaguc auggaauuuc aacaaaagaa caaccgccuc uuagaaauca      660

cccgagaauu uuccgucaac gcgggaguca caacccccgu uucuacguau augcucacca      720

acuccgaacu ccuuucccuc auaaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguccaaauc guccgacaac aauccuacuc uauuaugugc aucaucaaag      840

aagaaguucu cgccuacguc guccaacuac cccucuacgg cgugaucgac acccccugcu      900

ggaaacuaca caccucaccc cucugcacca ccaacaccaa ggaaggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgcugg cuccgucuca uucuucccgc     1020

aagccgaaac uugcaaagua ugcuccaaca gaguauucug cgacaccaug aacucacuaa     1080

cccucccuuc cgaagucaac cuuugcaacg uugacauauu caacccaaag uacgauugca     1140

aaauuaugac auccaaaaca gaugucuccu ccuccgucau cacaucccuc ggugccauug     1200

uaucaugcua cggaaaaacc aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa     1260

ccuucucaaa cggcugcgau uacgucucaa acaaaggagu cgacacaguc uccgucggaa     1320

acacccuaua cuacgucaac aaacaagaag gccaaucccu guacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc cgagcgacga guucgacgcc uccaucucac     1440

aagucaauga aaagaucaac caaucccuug ccuucauccg gaaaucggac gaacuccuac     1500

acaacgugaa cgcuggaaaa ucaaccacca acaucaugau cacaaccauc auuaucguca     1560

ucaucgucau acuccucucc cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu     1620

ccacccccgu cacccugucc aaagaccaac ucuccggaau caacaacauc gccuucucaa     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6137
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6137
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6138
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6138
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

ccacccccgu gacccugagc aaggaccagc uguccggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6139
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6139
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6140
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6140
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

caacaccugu gaccuugagu aaggaucagc ugucugggau uaacaauauc gcuuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6141
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6141
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6142
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6142
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgca     1620

gcacaccggu gacccugucu aaggaucagc uuuccggaau uaacaauauc gcguucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6143
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau      120

uaacagcagu aacauucugu uuugccuccg gacaaaacau aacagaagaa uuuuaucaau      180

caacaugcuc ugcaguaucc aaagguuacu uaggcgcacu acgcacugga ugguauacau      240

caguaauaac aauagaacua ucaaacauaa aagaaaauaa auguaacggu acugacgcaa      300

aagugaaacu aauuaaacaa gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa      360

ugcuaaugug cucaacaccc gcaaccggau caggaucagc cauagccucc ggagucgcag      420

uaugcaaagu auuacaucuu gaaggagaag uaaauaaaau aaaaucagca uuacuaucca      480

caaauaaagc cguaguauca cuaucaaacg guguauccgu ccuuacauuc aaaguauuag      540

aucuaaaaaa cuacauagau aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa      600

uucccaaccc agaaacaguc auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa      660

cacgagaauu uucaguaaac gcaggaguaa ccacaccagu aaguacauac augcucacca      720

acucagaauu auuaucacuu auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa      780

ugucaaacaa uguccaaauu guuagacaac aaucauacuc uauaaugugu auaauaaaag      840

aagaaguacu agcuuacgua guucaauuac cacuauaugg cguaauagau acaccuugcu      900

ggaaacuaca uacaucucca uuauguacaa cuaacacaaa agaaggaucu aacauaugcc      960

uaacacgcac agaucgagga ugguacugcg auaaugcagg uuccguauca uucuuuccac     1020

aagcagaaac auguaaagua ugcucaaaca gaguauucug ugacacuaug aacuccuuaa     1080

cccuacccuc agaagucaau cuaugcaacg uugacauauu uaacccaaaa uacgacugua     1140

aaaucaugac aucuaaaaca gacguaucau caucaguuau uacaucccua ggagcaauag     1200

uaucuugcua cggaaaaaca aaauguacag cauccaacaa aaacaaagga auaaucaaaa     1260

cauucucaaa cggcugcgac uacguaucaa acaaaggugu agacacagua ucaguaggaa     1320

auacuuuaua uuacguaaau aaacaagaag gacaaucucu auacguuaaa ggcgaaccua     1380

uuauaaacuu cuacgaccca cucguauucc cuucagacga auuugacgca ucuauauccc     1440

aaguuaacga aaaaaucaac caaucauuag ccuuuauaag aaaauccgac gaauuauuac     1500

auaacgucaa cgcuggaaaa ucaacaacua acauaaugau aaccacaaua auaauaguca     1560

ucauaguuau auuacuaagu cuaauagccg uaggccuccu acuuuauugc aaagcaagau     1620

caacaccagu aacauuaucc aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa     1680

acuagggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6144
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgcaauc acaaccauac      120

uaacugcagu uacuuucugc uucgcauccg gccaaaacau caccgaagag uucuaccaau      180

caaccugcuc cgcagucucc aaaggauacc ucggagcccu ucgcaccggc ugguacaccu      240

ccgucauaac caucgaacuc ucaaacauaa aagaaaacaa augcaacggc acagacgcga      300

aagucaaacu uaucaaacaa gaacucgaca aauacaaaaa cgccgucacc gaccugcaga      360

ugcucaugug cucaaccccc gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caagucagcc cuccucucca      480

ccaacaaagc cgucgucucu cucucaaacg gcguauccgu ccucacauuc aaaguccucg      540

accucaaaaa cuacaucgac aaacaacuuc uccccauccu aaacaaacaa ucaugcucca      600

uccccaaccc cgaaacaguc auggaauuuc aacaaaagaa caaccgccuc uuagaaauca      660

cccgagaauu uuccgucaac gcgggaguca caacccccgu uucuacguau augcucacca      720

acuccgaacu ccuuucccuc auaaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguccaaauc guccgacaac aauccuacuc uauuaugugc aucaucaaag      840

aagaaguucu cgccuacguc guccaacuac cccucuacgg cgugaucgac acccccugcu      900

ggaaacuaca caccucaccc cucugcacca ccaacaccaa ggaaggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgcugg cuccgucuca uucuucccgc     1020

aagccgaaac uugcaaagua ugcuccaaca gaguauucug cgacaccaug aacucacuaa     1080

cccucccuuc cgaagucaac cuuugcaacg uugacauauu caacccaaag uacgauugca     1140

aaauuaugac auccaaaaca gaugucuccu ccuccgucau cacaucccuc ggugccauug     1200

uaucaugcua cggaaaaacc aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa     1260

ccuucucaaa cggcugcgau uacgucucaa acaaaggagu cgacacaguc uccgucggaa     1320

acacccuaua cuacgucaac aaacaagaag gccaaucccu guacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc cgagcgacga guucgacgcc uccaucucac     1440

aagucaauga aaagaucaac caaucccuug ccuucauccg gaaaucggac gaacuccuac     1500

acaacgugaa cgcuggaaaa ucaaccacca acaucaugau cacaaccauc auuaucguca     1560

ucaucgucau acuccucucc cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu     1620

ccacccccgu cacccugucc aaagaccaac ucuccggaau caacaacauc gccuucucaa     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6145
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6145
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6146
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6146
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcuccac ccccgugacc     1680

cugagcaagg accagcuguc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6147
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6147
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6148
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6148
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggucaac accugugacc     1680

uugaguaagg aucagcuguc ugggauuaac aauaucgcuu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6149
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6149
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6150
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6150
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcagcac accggugacc     1680

cugucuaagg aucagcuuuc cggaauuaac aauaucgcgu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6151
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6151
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaaucuu aaaagcaaau gcuauaacca caauauuaac agcaguaaca      180

uucuguuuug ccuccggaca aaacauaaca gaagaauuuu aucaaucaac augcucugca      240

guauccaaag guuacuuagg cgcacuacgc acuggauggu auacaucagu aauaacaaua      300

gaacuaucaa acauaaaaga aaauaaaugu aacgguacug acgcaaaagu gaaacuaauu      360

aaacaagaac ucgacaaaua caaaaaugcu guaacagacc uacaaaugcu aaugugcuca      420

acacccgcaa ccggaucagg aucagccaua gccuccggag ucgcaguaug caaaguauua      480

caucuugaag gagaaguaaa uaaaauaaaa ucagcauuac uauccacaaa uaaagccgua      540

guaucacuau caaacggugu auccguccuu acauucaaag uauuagaucu aaaaaacuac      600

auagauaaac aacuacuacc caucuuaaac aaacaaucau gcucaauucc caacccagaa      660

acagucaugg aauuucaaca aaaaaacaac agacucuuag aaauaacacg agaauuuuca      720

guaaacgcag gaguaaccac accaguaagu acauacaugc ucaccaacuc agaauuauua      780

ucacuuauua acgacaugcc aauuacaaac gaccaaaaaa aauuaauguc aaacaauguc      840

caaauuguua gacaacaauc auacucuaua auguguauaa uaaaagaaga aguacuagcu      900

uacguaguuc aauuaccacu auauggcgua auagauacac cuugcuggaa acuacauaca      960

ucuccauuau guacaacuaa cacaaaagaa ggaucuaaca uaugccuaac acgcacagau     1020

cgaggauggu acugcgauaa ugcagguucc guaucauucu uuccacaagc agaaacaugu     1080

aaaguaugcu caaacagagu auucugugac acuaugaacu ccuuaacccu acccucagaa     1140

gucaaucuau gcaacguuga cauauuuaac ccaaaauacg acuguaaaau caugacaucu     1200

aaaacagacg uaucaucauc aguuauuaca ucccuaggag caauaguauc uugcuacgga     1260

aaaacaaaau guacagcauc caacaaaaac aaaggaauaa ucaaaacauu cucaaacggc     1320

ugcgacuacg uaucaaacaa agguguagac acaguaucag uaggaaauac uuuauauuac     1380

guaaauaaac aagaaggaca aucucuauac guuaaaggcg aaccuauuau aaacuucuac     1440

gacccacucg uauucccuuc agacgaauuu gacgcaucua uaucccaagu uaacgaaaaa     1500

aucaaccaau cauuagccuu uauaagaaaa uccgacgaau uauuacauaa cgucaacgcu     1560

ggaaaaucaa caacuaacau aaugauaacc acaauaauaa uagucaucau aguuauauua     1620

cuaagucuaa uagccguagg ccuccuacuu uauugcaaag caagaucaac accaguaaca     1680

uuauccaaag accaacucag cggcauaaac aauauagcuu uuucaaacua gggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6152
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6152
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gcaaucacaa ccauacuaac ugcaguuacu      180

uucugcuucg cauccggcca aaacaucacc gaagaguucu accaaucaac cugcuccgca      240

gucuccaaag gauaccucgg agcccuucgc accggcuggu acaccuccgu cauaaccauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcacag acgcgaaagu caaacuuauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucaccgacc ugcagaugcu caugugcuca      420

acccccgcca caggaagcgg cucugcuauc gcuuccggcg ucgccgucug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaag ucagcccucc ucuccaccaa caaagccguc      540

gucucucucu caaacggcgu auccguccuc acauucaaag uccucgaccu caaaaacuac      600

aucgacaaac aacuucuccc cauccuaaac aaacaaucau gcuccauccc caaccccgaa      660

acagucaugg aauuucaaca aaagaacaac cgccucuuag aaaucacccg agaauuuucc      720

gucaacgcgg gagucacaac ccccguuucu acguauaugc ucaccaacuc cgaacuccuu      780

ucccucauaa acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacguc      840

caaaucgucc gacaacaauc cuacucuauu augugcauca ucaaagaaga aguucucgcc      900

uacgucgucc aacuaccccu cuacggcgug aucgacaccc ccugcuggaa acuacacacc      960

ucaccccucu gcaccaccaa caccaaggaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgcuggcucc gucucauucu ucccgcaagc cgaaacuugc     1080

aaaguaugcu ccaacagagu auucugcgac accaugaacu cacuaacccu cccuuccgaa     1140

gucaaccuuu gcaacguuga cauauucaac ccaaaguacg auugcaaaau uaugacaucc     1200

aaaacagaug ucuccuccuc cgucaucaca ucccucggug ccauuguauc augcuacgga     1260

aaaaccaaau gcaccgcauc caacaaaaac aaaggaauca ucaaaaccuu cucaaacggc     1320

ugcgauuacg ucucaaacaa aggagucgac acagucuccg ucggaaacac ccuauacuac     1380

gucaacaaac aagaaggcca aucccuguac gucaaaggag aacccaucau caacuucuac     1440

gacccccucg ucuucccgag cgacgaguuc gacgccucca ucucacaagu caaugaaaag     1500

aucaaccaau cccuugccuu cauccggaaa ucggacgaac uccuacacaa cgugaacgcu     1560

ggaaaaucaa ccaccaacau caugaucaca accaucauua ucgucaucau cgucauacuc     1620

cucucccuaa ucgccgucgg ccuccuccug uauugcaaag cucgcuccac ccccgucacc     1680

cuguccaaag accaacucuc cggaaucaac aacaucgccu ucucaaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6153
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6153
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6154
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6154
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcuc cacccccgug acccugagca aggaccagcu guccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6155
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6155
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6156
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6156
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacgguc aacaccugug accuugagua aggaucagcu gucugggauu     1680

aacaauaucg cuuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6157
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6157
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6158
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6158
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcag cacaccggug acccugucua aggaucagcu uuccggaauu     1680

aacaauaucg cguucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6159
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6159
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau cuuaaaagca      120

aaugcuauaa ccacaauauu aacagcagua acauucuguu uugccuccgg acaaaacaua      180

acagaagaau uuuaucaauc aacaugcucu gcaguaucca aagguuacuu aggcgcacua      240

cgcacuggau gguauacauc aguaauaaca auagaacuau caaacauaaa agaaaauaaa      300

uguaacggua cugacgcaaa agugaaacua auuaaacaag aacucgacaa auacaaaaau      360

gcuguaacag accuacaaau gcuaaugugc ucaacacccg caaccggauc aggaucagcc      420

auagccuccg gagucgcagu augcaaagua uuacaucuug aaggagaagu aaauaaaaua      480

aaaucagcau uacuauccac aaauaaagcc guaguaucac uaucaaacgg uguauccguc      540

cuuacauuca aaguauuaga ucuaaaaaac uacauagaua aacaacuacu acccaucuua      600

aacaaacaau caugcucaau ucccaaccca gaaacaguca uggaauuuca acaaaaaaac      660

aacagacucu uagaaauaac acgagaauuu ucaguaaacg caggaguaac cacaccagua      720

aguacauaca ugcucaccaa cucagaauua uuaucacuua uuaacgacau gccaauuaca      780

aacgaccaaa aaaaauuaau gucaaacaau guccaaauug uuagacaaca aucauacucu      840

auaaugugua uaauaaaaga agaaguacua gcuuacguag uucaauuacc acuauauggc      900

guaauagaua caccuugcug gaaacuacau acaucuccau uauguacaac uaacacaaaa      960

gaaggaucua acauaugccu aacacgcaca gaucgaggau gguacugcga uaaugcaggu     1020

uccguaucau ucuuuccaca agcagaaaca uguaaaguau gcucaaacag aguauucugu     1080

gacacuauga acuccuuaac ccuacccuca gaagucaauc uaugcaacgu ugacauauuu     1140

aacccaaaau acgacuguaa aaucaugaca ucuaaaacag acguaucauc aucaguuauu     1200

acaucccuag gagcaauagu aucuugcuac ggaaaaacaa aauguacagc auccaacaaa     1260

aacaaaggaa uaaucaaaac auucucaaac ggcugcgacu acguaucaaa caaaggugua     1320

gacacaguau caguaggaaa uacuuuauau uacguaaaua aacaagaagg acaaucucua     1380

uacguuaaag gcgaaccuau uauaaacuuc uacgacccac ucguauuccc uucagacgaa     1440

uuugacgcau cuauauccca aguuaacgaa aaaaucaacc aaucauuagc cuuuauaaga     1500

aaauccgacg aauuauuaca uaacgucaac gcuggaaaau caacaacuaa cauaaugaua     1560

accacaauaa uaauagucau cauaguuaua uuacuaaguc uaauagccgu aggccuccua     1620

cuuuauugca aagcaagauc aacaccagua acauuaucca aagaccaacu cagcggcaua     1680

aacaauauag cuuuuucaaa cuagggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6160
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6160
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgcaauca caaccauacu aacugcaguu acuuucugcu ucgcauccgg ccaaaacauc      180

accgaagagu ucuaccaauc aaccugcucc gcagucucca aaggauaccu cggagcccuu      240

cgcaccggcu gguacaccuc cgucauaacc aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca cagacgcgaa agucaaacuu aucaaacaag aacucgacaa auacaaaaac      360

gccgucaccg accugcagau gcucaugugc ucaacccccg ccacaggaag cggcucugcu      420

aucgcuuccg gcgucgccgu cugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aagucagccc uccucuccac caacaaagcc gucgucucuc ucucaaacgg cguauccguc      540

cucacauuca aaguccucga ccucaaaaac uacaucgaca aacaacuucu ccccauccua      600

aacaaacaau caugcuccau ccccaacccc gaaacaguca uggaauuuca acaaaagaac      660

aaccgccucu uagaaaucac ccgagaauuu uccgucaacg cgggagucac aacccccguu      720

ucuacguaua ugcucaccaa cuccgaacuc cuuucccuca uaaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guccaaaucg uccgacaaca auccuacucu      840

auuaugugca ucaucaaaga agaaguucuc gccuacgucg uccaacuacc ccucuacggc      900

gugaucgaca cccccugcug gaaacuacac accucacccc ucugcaccac caacaccaag      960

gaaggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgcuggc     1020

uccgucucau ucuucccgca agccgaaacu ugcaaaguau gcuccaacag aguauucugc     1080

gacaccauga acucacuaac ccucccuucc gaagucaacc uuugcaacgu ugacauauuc     1140

aacccaaagu acgauugcaa aauuaugaca uccaaaacag augucuccuc cuccgucauc     1200

acaucccucg gugccauugu aucaugcuac ggaaaaacca aaugcaccgc auccaacaaa     1260

aacaaaggaa ucaucaaaac cuucucaaac ggcugcgauu acgucucaaa caaaggaguc     1320

gacacagucu ccgucggaaa cacccuauac uacgucaaca aacaagaagg ccaaucccug     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc ucgucuuccc gagcgacgag     1440

uucgacgccu ccaucucaca agucaaugaa aagaucaacc aaucccuugc cuucauccgg     1500

aaaucggacg aacuccuaca caacgugaac gcuggaaaau caaccaccaa caucaugauc     1560

acaaccauca uuaucgucau caucgucaua cuccucuccc uaaucgccgu cggccuccuc     1620

cuguauugca aagcucgcuc cacccccguc acccugucca aagaccaacu cuccggaauc     1680

aacaacaucg ccuucucaaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6161
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6161
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6162
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6162
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcuccac ccccgugacc     1680

cugagcaagg accagcuguc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6163
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6163
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6164
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6164
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggucaac accugugacc     1680

uugaguaagg aucagcuguc ugggauuaac aauaucgcuu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6165
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6165
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6166
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6166
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcagcac accggugacc     1680

cugucuaagg aucagcuuuc cggaauuaac aauaucgcgu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6167
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6167
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaaucuu aaaagcaaau gcuauaacca caauauuaac agcaguaaca      180

uucuguuuug ccuccggaca aaacauaaca gaagaauuuu aucaaucaac augcucugca      240

guauccaaag guuacuuagg cgcacuacgc acuggauggu auacaucagu aauaacaaua      300

gaacuaucaa acauaaaaga aaauaaaugu aacgguacug acgcaaaagu gaaacuaauu      360

aaacaagaac ucgacaaaua caaaaaugcu guaacagacc uacaaaugcu aaugugcuca      420

acacccgcaa ccggaucagg aucagccaua gccuccggag ucgcaguaug caaaguauua      480

caucuugaag gagaaguaaa uaaaauaaaa ucagcauuac uauccacaaa uaaagccgua      540

guaucacuau caaacggugu auccguccuu acauucaaag uauuagaucu aaaaaacuac      600

auagauaaac aacuacuacc caucuuaaac aaacaaucau gcucaauucc caacccagaa      660

acagucaugg aauuucaaca aaaaaacaac agacucuuag aaauaacacg agaauuuuca      720

guaaacgcag gaguaaccac accaguaagu acauacaugc ucaccaacuc agaauuauua      780

ucacuuauua acgacaugcc aauuacaaac gaccaaaaaa aauuaauguc aaacaauguc      840

caaauuguua gacaacaauc auacucuaua auguguauaa uaaaagaaga aguacuagcu      900

uacguaguuc aauuaccacu auauggcgua auagauacac cuugcuggaa acuacauaca      960

ucuccauuau guacaacuaa cacaaaagaa ggaucuaaca uaugccuaac acgcacagau     1020

cgaggauggu acugcgauaa ugcagguucc guaucauucu uuccacaagc agaaacaugu     1080

aaaguaugcu caaacagagu auucugugac acuaugaacu ccuuaacccu acccucagaa     1140

gucaaucuau gcaacguuga cauauuuaac ccaaaauacg acuguaaaau caugacaucu     1200

aaaacagacg uaucaucauc aguuauuaca ucccuaggag caauaguauc uugcuacgga     1260

aaaacaaaau guacagcauc caacaaaaac aaaggaauaa ucaaaacauu cucaaacggc     1320

ugcgacuacg uaucaaacaa agguguagac acaguaucag uaggaaauac uuuauauuac     1380

guaaauaaac aagaaggaca aucucuauac guuaaaggcg aaccuauuau aaacuucuac     1440

gacccacucg uauucccuuc agacgaauuu gacgcaucua uaucccaagu uaacgaaaaa     1500

aucaaccaau cauuagccuu uauaagaaaa uccgacgaau uauuacauaa cgucaacgcu     1560

ggaaaaucaa caacuaacau aaugauaacc acaauaauaa uagucaucau aguuauauua     1620

cuaagucuaa uagccguagg ccuccuacuu uauugcaaag caagaucaac accaguaaca     1680

uuauccaaag accaacucag cggcauaaac aauauagcuu uuucaaacua gggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6168
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6168
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gcaaucacaa ccauacuaac ugcaguuacu      180

uucugcuucg cauccggcca aaacaucacc gaagaguucu accaaucaac cugcuccgca      240

gucuccaaag gauaccucgg agcccuucgc accggcuggu acaccuccgu cauaaccauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcacag acgcgaaagu caaacuuauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucaccgacc ugcagaugcu caugugcuca      420

acccccgcca caggaagcgg cucugcuauc gcuuccggcg ucgccgucug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaag ucagcccucc ucuccaccaa caaagccguc      540

gucucucucu caaacggcgu auccguccuc acauucaaag uccucgaccu caaaaacuac      600

aucgacaaac aacuucuccc cauccuaaac aaacaaucau gcuccauccc caaccccgaa      660

acagucaugg aauuucaaca aaagaacaac cgccucuuag aaaucacccg agaauuuucc      720

gucaacgcgg gagucacaac ccccguuucu acguauaugc ucaccaacuc cgaacuccuu      780

ucccucauaa acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacguc      840

caaaucgucc gacaacaauc cuacucuauu augugcauca ucaaagaaga aguucucgcc      900

uacgucgucc aacuaccccu cuacggcgug aucgacaccc ccugcuggaa acuacacacc      960

ucaccccucu gcaccaccaa caccaaggaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgcuggcucc gucucauucu ucccgcaagc cgaaacuugc     1080

aaaguaugcu ccaacagagu auucugcgac accaugaacu cacuaacccu cccuuccgaa     1140

gucaaccuuu gcaacguuga cauauucaac ccaaaguacg auugcaaaau uaugacaucc     1200

aaaacagaug ucuccuccuc cgucaucaca ucccucggug ccauuguauc augcuacgga     1260

aaaaccaaau gcaccgcauc caacaaaaac aaaggaauca ucaaaaccuu cucaaacggc     1320

ugcgauuacg ucucaaacaa aggagucgac acagucuccg ucggaaacac ccuauacuac     1380

gucaacaaac aagaaggcca aucccuguac gucaaaggag aacccaucau caacuucuac     1440

gacccccucg ucuucccgag cgacgaguuc gacgccucca ucucacaagu caaugaaaag     1500

aucaaccaau cccuugccuu cauccggaaa ucggacgaac uccuacacaa cgugaacgcu     1560

ggaaaaucaa ccaccaacau caugaucaca accaucauua ucgucaucau cgucauacuc     1620

cucucccuaa ucgccgucgg ccuccuccug uauugcaaag cucgcuccac ccccgucacc     1680

cuguccaaag accaacucuc cggaaucaac aacaucgccu ucucaaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6169
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6169
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6170
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6170
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcuc cacccccgug acccugagca aggaccagcu guccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6171
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6171
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6172
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6172
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacgguc aacaccugug accuugagua aggaucagcu gucugggauu     1680

aacaauaucg cuuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6173
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6173
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6174
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6174
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcag cacaccggug acccugucua aggaucagcu uuccggaauu     1680

aacaauaucg cguucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6175
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6175
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau cuuaaaagca      120

aaugcuauaa ccacaauauu aacagcagua acauucuguu uugccuccgg acaaaacaua      180

acagaagaau uuuaucaauc aacaugcucu gcaguaucca aagguuacuu aggcgcacua      240

cgcacuggau gguauacauc aguaauaaca auagaacuau caaacauaaa agaaaauaaa      300

uguaacggua cugacgcaaa agugaaacua auuaaacaag aacucgacaa auacaaaaau      360

gcuguaacag accuacaaau gcuaaugugc ucaacacccg caaccggauc aggaucagcc      420

auagccuccg gagucgcagu augcaaagua uuacaucuug aaggagaagu aaauaaaaua      480

aaaucagcau uacuauccac aaauaaagcc guaguaucac uaucaaacgg uguauccguc      540

cuuacauuca aaguauuaga ucuaaaaaac uacauagaua aacaacuacu acccaucuua      600

aacaaacaau caugcucaau ucccaaccca gaaacaguca uggaauuuca acaaaaaaac      660

aacagacucu uagaaauaac acgagaauuu ucaguaaacg caggaguaac cacaccagua      720

aguacauaca ugcucaccaa cucagaauua uuaucacuua uuaacgacau gccaauuaca      780

aacgaccaaa aaaaauuaau gucaaacaau guccaaauug uuagacaaca aucauacucu      840

auaaugugua uaauaaaaga agaaguacua gcuuacguag uucaauuacc acuauauggc      900

guaauagaua caccuugcug gaaacuacau acaucuccau uauguacaac uaacacaaaa      960

gaaggaucua acauaugccu aacacgcaca gaucgaggau gguacugcga uaaugcaggu     1020

uccguaucau ucuuuccaca agcagaaaca uguaaaguau gcucaaacag aguauucugu     1080

gacacuauga acuccuuaac ccuacccuca gaagucaauc uaugcaacgu ugacauauuu     1140

aacccaaaau acgacuguaa aaucaugaca ucuaaaacag acguaucauc aucaguuauu     1200

acaucccuag gagcaauagu aucuugcuac ggaaaaacaa aauguacagc auccaacaaa     1260

aacaaaggaa uaaucaaaac auucucaaac ggcugcgacu acguaucaaa caaaggugua     1320

gacacaguau caguaggaaa uacuuuauau uacguaaaua aacaagaagg acaaucucua     1380

uacguuaaag gcgaaccuau uauaaacuuc uacgacccac ucguauuccc uucagacgaa     1440

uuugacgcau cuauauccca aguuaacgaa aaaaucaacc aaucauuagc cuuuauaaga     1500

aaauccgacg aauuauuaca uaacgucaac gcuggaaaau caacaacuaa cauaaugaua     1560

accacaauaa uaauagucau cauaguuaua uuacuaaguc uaauagccgu aggccuccua     1620

cuuuauugca aagcaagauc aacaccagua acauuaucca aagaccaacu cagcggcaua     1680

aacaauauag cuuuuucaaa cuagggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6176
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6176
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgcaauca caaccauacu aacugcaguu acuuucugcu ucgcauccgg ccaaaacauc      180

accgaagagu ucuaccaauc aaccugcucc gcagucucca aaggauaccu cggagcccuu      240

cgcaccggcu gguacaccuc cgucauaacc aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca cagacgcgaa agucaaacuu aucaaacaag aacucgacaa auacaaaaac      360

gccgucaccg accugcagau gcucaugugc ucaacccccg ccacaggaag cggcucugcu      420

aucgcuuccg gcgucgccgu cugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aagucagccc uccucuccac caacaaagcc gucgucucuc ucucaaacgg cguauccguc      540

cucacauuca aaguccucga ccucaaaaac uacaucgaca aacaacuucu ccccauccua      600

aacaaacaau caugcuccau ccccaacccc gaaacaguca uggaauuuca acaaaagaac      660

aaccgccucu uagaaaucac ccgagaauuu uccgucaacg cgggagucac aacccccguu      720

ucuacguaua ugcucaccaa cuccgaacuc cuuucccuca uaaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guccaaaucg uccgacaaca auccuacucu      840

auuaugugca ucaucaaaga agaaguucuc gccuacgucg uccaacuacc ccucuacggc      900

gugaucgaca cccccugcug gaaacuacac accucacccc ucugcaccac caacaccaag      960

gaaggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgcuggc     1020

uccgucucau ucuucccgca agccgaaacu ugcaaaguau gcuccaacag aguauucugc     1080

gacaccauga acucacuaac ccucccuucc gaagucaacc uuugcaacgu ugacauauuc     1140

aacccaaagu acgauugcaa aauuaugaca uccaaaacag augucuccuc cuccgucauc     1200

acaucccucg gugccauugu aucaugcuac ggaaaaacca aaugcaccgc auccaacaaa     1260

aacaaaggaa ucaucaaaac cuucucaaac ggcugcgauu acgucucaaa caaaggaguc     1320

gacacagucu ccgucggaaa cacccuauac uacgucaaca aacaagaagg ccaaucccug     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc ucgucuuccc gagcgacgag     1440

uucgacgccu ccaucucaca agucaaugaa aagaucaacc aaucccuugc cuucauccgg     1500

aaaucggacg aacuccuaca caacgugaac gcuggaaaau caaccaccaa caucaugauc     1560

acaaccauca uuaucgucau caucgucaua cuccucuccc uaaucgccgu cggccuccuc     1620

cuguauugca aagcucgcuc cacccccguc acccugucca aagaccaacu cuccggaauc     1680

aacaacaucg ccuucucaaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6177
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6177
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6178
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6178
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcuc cacccccgug acccugagca aggaccagcu guccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6179
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6179
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6180
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6180
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacgguc aacaccugug accuugagua aggaucagcu gucugggauu     1680

aacaauaucg cuuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6181
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6181
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6182
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6182
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcag cacaccggug acccugucua aggaucagcu uuccggaauu     1680

aacaauaucg cguucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6183
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6183
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau cuuaaaagca      120

aaugcuauaa ccacaauauu aacagcagua acauucuguu uugccuccgg acaaaacaua      180

acagaagaau uuuaucaauc aacaugcucu gcaguaucca aagguuacuu aggcgcacua      240

cgcacuggau gguauacauc aguaauaaca auagaacuau caaacauaaa agaaaauaaa      300

uguaacggua cugacgcaaa agugaaacua auuaaacaag aacucgacaa auacaaaaau      360

gcuguaacag accuacaaau gcuaaugugc ucaacacccg caaccggauc aggaucagcc      420

auagccuccg gagucgcagu augcaaagua uuacaucuug aaggagaagu aaauaaaaua      480

aaaucagcau uacuauccac aaauaaagcc guaguaucac uaucaaacgg uguauccguc      540

cuuacauuca aaguauuaga ucuaaaaaac uacauagaua aacaacuacu acccaucuua      600

aacaaacaau caugcucaau ucccaaccca gaaacaguca uggaauuuca acaaaaaaac      660

aacagacucu uagaaauaac acgagaauuu ucaguaaacg caggaguaac cacaccagua      720

aguacauaca ugcucaccaa cucagaauua uuaucacuua uuaacgacau gccaauuaca      780

aacgaccaaa aaaaauuaau gucaaacaau guccaaauug uuagacaaca aucauacucu      840

auaaugugua uaauaaaaga agaaguacua gcuuacguag uucaauuacc acuauauggc      900

guaauagaua caccuugcug gaaacuacau acaucuccau uauguacaac uaacacaaaa      960

gaaggaucua acauaugccu aacacgcaca gaucgaggau gguacugcga uaaugcaggu     1020

uccguaucau ucuuuccaca agcagaaaca uguaaaguau gcucaaacag aguauucugu     1080

gacacuauga acuccuuaac ccuacccuca gaagucaauc uaugcaacgu ugacauauuu     1140

aacccaaaau acgacuguaa aaucaugaca ucuaaaacag acguaucauc aucaguuauu     1200

acaucccuag gagcaauagu aucuugcuac ggaaaaacaa aauguacagc auccaacaaa     1260

aacaaaggaa uaaucaaaac auucucaaac ggcugcgacu acguaucaaa caaaggugua     1320

gacacaguau caguaggaaa uacuuuauau uacguaaaua aacaagaagg acaaucucua     1380

uacguuaaag gcgaaccuau uauaaacuuc uacgacccac ucguauuccc uucagacgaa     1440

uuugacgcau cuauauccca aguuaacgaa aaaaucaacc aaucauuagc cuuuauaaga     1500

aaauccgacg aauuauuaca uaacgucaac gcuggaaaau caacaacuaa cauaaugaua     1560

accacaauaa uaauagucau cauaguuaua uuacuaaguc uaauagccgu aggccuccua     1620

cuuuauugca aagcaagauc aacaccagua acauuaucca aagaccaacu cagcggcaua     1680

aacaauauag cuuuuucaaa cuagggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6184
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6184
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgcaauca caaccauacu aacugcaguu acuuucugcu ucgcauccgg ccaaaacauc      180

accgaagagu ucuaccaauc aaccugcucc gcagucucca aaggauaccu cggagcccuu      240

cgcaccggcu gguacaccuc cgucauaacc aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca cagacgcgaa agucaaacuu aucaaacaag aacucgacaa auacaaaaac      360

gccgucaccg accugcagau gcucaugugc ucaacccccg ccacaggaag cggcucugcu      420

aucgcuuccg gcgucgccgu cugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aagucagccc uccucuccac caacaaagcc gucgucucuc ucucaaacgg cguauccguc      540

cucacauuca aaguccucga ccucaaaaac uacaucgaca aacaacuucu ccccauccua      600

aacaaacaau caugcuccau ccccaacccc gaaacaguca uggaauuuca acaaaagaac      660

aaccgccucu uagaaaucac ccgagaauuu uccgucaacg cgggagucac aacccccguu      720

ucuacguaua ugcucaccaa cuccgaacuc cuuucccuca uaaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guccaaaucg uccgacaaca auccuacucu      840

auuaugugca ucaucaaaga agaaguucuc gccuacgucg uccaacuacc ccucuacggc      900

gugaucgaca cccccugcug gaaacuacac accucacccc ucugcaccac caacaccaag      960

gaaggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgcuggc     1020

uccgucucau ucuucccgca agccgaaacu ugcaaaguau gcuccaacag aguauucugc     1080

gacaccauga acucacuaac ccucccuucc gaagucaacc uuugcaacgu ugacauauuc     1140

aacccaaagu acgauugcaa aauuaugaca uccaaaacag augucuccuc cuccgucauc     1200

acaucccucg gugccauugu aucaugcuac ggaaaaacca aaugcaccgc auccaacaaa     1260

aacaaaggaa ucaucaaaac cuucucaaac ggcugcgauu acgucucaaa caaaggaguc     1320

gacacagucu ccgucggaaa cacccuauac uacgucaaca aacaagaagg ccaaucccug     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc ucgucuuccc gagcgacgag     1440

uucgacgccu ccaucucaca agucaaugaa aagaucaacc aaucccuugc cuucauccgg     1500

aaaucggacg aacuccuaca caacgugaac gcuggaaaau caaccaccaa caucaugauc     1560

acaaccauca uuaucgucau caucgucaua cuccucuccc uaaucgccgu cggccuccuc     1620

cuguauugca aagcucgcuc cacccccguc acccugucca aagaccaacu cuccggaauc     1680

aacaacaucg ccuucucaaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6185
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6185
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6186
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6186
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcuccacccc cgugacccug agcaaggacc agcuguccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6187
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6187
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6188
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6188
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggucaacacc ugugaccuug aguaaggauc agcugucugg gauuaacaau     1680

aucgcuuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6189
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6189
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6190
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6190
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcagcacacc ggugacccug ucuaaggauc agcuuuccgg aauuaacaau     1680

aucgcguuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6191
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6191
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaaucuuaaa agcaaaugcu      120

auaaccacaa uauuaacagc aguaacauuc uguuuugccu ccggacaaaa cauaacagaa      180

gaauuuuauc aaucaacaug cucugcagua uccaaagguu acuuaggcgc acuacgcacu      240

ggaugguaua caucaguaau aacaauagaa cuaucaaaca uaaaagaaaa uaaauguaac      300

gguacugacg caaaagugaa acuaauuaaa caagaacucg acaaauacaa aaaugcugua      360

acagaccuac aaaugcuaau gugcucaaca cccgcaaccg gaucaggauc agccauagcc      420

uccggagucg caguaugcaa aguauuacau cuugaaggag aaguaaauaa aauaaaauca      480

gcauuacuau ccacaaauaa agccguagua ucacuaucaa acgguguauc cguccuuaca      540

uucaaaguau uagaucuaaa aaacuacaua gauaaacaac uacuacccau cuuaaacaaa      600

caaucaugcu caauucccaa cccagaaaca gucauggaau uucaacaaaa aaacaacaga      660

cucuuagaaa uaacacgaga auuuucagua aacgcaggag uaaccacacc aguaaguaca      720

uacaugcuca ccaacucaga auuauuauca cuuauuaacg acaugccaau uacaaacgac      780

caaaaaaaau uaaugucaaa caauguccaa auuguuagac aacaaucaua cucuauaaug      840

uguauaauaa aagaagaagu acuagcuuac guaguucaau uaccacuaua uggcguaaua      900

gauacaccuu gcuggaaacu acauacaucu ccauuaugua caacuaacac aaaagaagga      960

ucuaacauau gccuaacacg cacagaucga ggaugguacu gcgauaaugc agguuccgua     1020

ucauucuuuc cacaagcaga aacauguaaa guaugcucaa acagaguauu cugugacacu     1080

augaacuccu uaacccuacc cucagaaguc aaucuaugca acguugacau auuuaaccca     1140

aaauacgacu guaaaaucau gacaucuaaa acagacguau caucaucagu uauuacaucc     1200

cuaggagcaa uaguaucuug cuacggaaaa acaaaaugua cagcauccaa caaaaacaaa     1260

ggaauaauca aaacauucuc aaacggcugc gacuacguau caaacaaagg uguagacaca     1320

guaucaguag gaaauacuuu auauuacgua aauaaacaag aaggacaauc ucuauacguu     1380

aaaggcgaac cuauuauaaa cuucuacgac ccacucguau ucccuucaga cgaauuugac     1440

gcaucuauau cccaaguuaa cgaaaaaauc aaccaaucau uagccuuuau aagaaaaucc     1500

gacgaauuau uacauaacgu caacgcugga aaaucaacaa cuaacauaau gauaaccaca     1560

auaauaauag ucaucauagu uauauuacua agucuaauag ccguaggccu ccuacuuuau     1620

ugcaaagcaa gaucaacacc aguaacauua uccaaagacc aacucagcgg cauaaacaau     1680

auagcuuuuu caaacuaggg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6192
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6192
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgca      120

aucacaacca uacuaacugc aguuacuuuc ugcuucgcau ccggccaaaa caucaccgaa      180

gaguucuacc aaucaaccug cuccgcaguc uccaaaggau accucggagc ccuucgcacc      240

ggcugguaca ccuccgucau aaccaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcacagacg cgaaagucaa acuuaucaaa caagaacucg acaaauacaa aaacgccguc      360

accgaccugc agaugcucau gugcucaacc cccgccacag gaagcggcuc ugcuaucgcu      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaguca      480

gcccuccucu ccaccaacaa agccgucguc ucucucucaa acggcguauc cguccucaca      540

uucaaagucc ucgaccucaa aaacuacauc gacaaacaac uucuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa ccccgaaaca gucauggaau uucaacaaaa gaacaaccgc      660

cucuuagaaa ucacccgaga auuuuccguc aacgcgggag ucacaacccc cguuucuacg      720

uauaugcuca ccaacuccga acuccuuucc cucauaaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguccaa aucguccgac aacaauccua cucuauuaug      840

ugcaucauca aagaagaagu ucucgccuac gucguccaac uaccccucua cggcgugauc      900

gacacccccu gcuggaaacu acacaccuca ccccucugca ccaccaacac caaggaaggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc uggcuccguc     1020

ucauucuucc cgcaagccga aacuugcaaa guaugcucca acagaguauu cugcgacacc     1080

augaacucac uaacccuccc uuccgaaguc aaccuuugca acguugacau auucaaccca     1140

aaguacgauu gcaaaauuau gacauccaaa acagaugucu ccuccuccgu caucacaucc     1200

cucggugcca uuguaucaug cuacggaaaa accaaaugca ccgcauccaa caaaaacaaa     1260

ggaaucauca aaaccuucuc aaacggcugc gauuacgucu caaacaaagg agucgacaca     1320

gucuccgucg gaaacacccu auacuacguc aacaaacaag aaggccaauc ccuguacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccucgucu ucccgagcga cgaguucgac     1440

gccuccaucu cacaagucaa ugaaaagauc aaccaauccc uugccuucau ccggaaaucg     1500

gacgaacucc uacacaacgu gaacgcugga aaaucaacca ccaacaucau gaucacaacc     1560

aucauuaucg ucaucaucgu cauacuccuc ucccuaaucg ccgucggccu ccuccuguau     1620

ugcaaagcuc gcuccacccc cgucacccug uccaaagacc aacucuccgg aaucaacaac     1680

aucgccuucu caaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6193
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6193
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6194
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6194
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cuccaccccc gugacccuga gcaaggacca gcuguccggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6195
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6195
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6196
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6196
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gucaacaccu gugaccuuga guaaggauca gcugucuggg     1680

auuaacaaua ucgcuuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6197
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6197
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6198
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6198
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cagcacaccg gugacccugu cuaaggauca gcuuuccgga     1680

auuaacaaua ucgcguucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6199
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6199
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aaucuuaaaa      120

gcaaaugcua uaaccacaau auuaacagca guaacauucu guuuugccuc cggacaaaac      180

auaacagaag aauuuuauca aucaacaugc ucugcaguau ccaaagguua cuuaggcgca      240

cuacgcacug gaugguauac aucaguaaua acaauagaac uaucaaacau aaaagaaaau      300

aaauguaacg guacugacgc aaaagugaaa cuaauuaaac aagaacucga caaauacaaa      360

aaugcuguaa cagaccuaca aaugcuaaug ugcucaacac ccgcaaccgg aucaggauca      420

gccauagccu ccggagucgc aguaugcaaa guauuacauc uugaaggaga aguaaauaaa      480

auaaaaucag cauuacuauc cacaaauaaa gccguaguau cacuaucaaa cgguguaucc      540

guccuuacau ucaaaguauu agaucuaaaa aacuacauag auaaacaacu acuacccauc      600

uuaaacaaac aaucaugcuc aauucccaac ccagaaacag ucauggaauu ucaacaaaaa      660

aacaacagac ucuuagaaau aacacgagaa uuuucaguaa acgcaggagu aaccacacca      720

guaaguacau acaugcucac caacucagaa uuauuaucac uuauuaacga caugccaauu      780

acaaacgacc aaaaaaaauu aaugucaaac aauguccaaa uuguuagaca acaaucauac      840

ucuauaaugu guauaauaaa agaagaagua cuagcuuacg uaguucaauu accacuauau      900

ggcguaauag auacaccuug cuggaaacua cauacaucuc cauuauguac aacuaacaca      960

aaagaaggau cuaacauaug ccuaacacgc acagaucgag gaugguacug cgauaaugca     1020

gguuccguau cauucuuucc acaagcagaa acauguaaag uaugcucaaa cagaguauuc     1080

ugugacacua ugaacuccuu aacccuaccc ucagaaguca aucuaugcaa cguugacaua     1140

uuuaacccaa aauacgacug uaaaaucaug acaucuaaaa cagacguauc aucaucaguu     1200

auuacauccc uaggagcaau aguaucuugc uacggaaaaa caaaauguac agcauccaac     1260

aaaaacaaag gaauaaucaa aacauucuca aacggcugcg acuacguauc aaacaaaggu     1320

guagacacag uaucaguagg aaauacuuua uauuacguaa auaaacaaga aggacaaucu     1380

cuauacguua aaggcgaacc uauuauaaac uucuacgacc cacucguauu cccuucagac     1440

gaauuugacg caucuauauc ccaaguuaac gaaaaaauca accaaucauu agccuuuaua     1500

agaaaauccg acgaauuauu acauaacguc aacgcuggaa aaucaacaac uaacauaaug     1560

auaaccacaa uaauaauagu caucauaguu auauuacuaa gucuaauagc cguaggccuc     1620

cuacuuuauu gcaaagcaag aucaacacca guaacauuau ccaaagacca acucagcggc     1680

auaaacaaua uagcuuuuuc aaacuaggga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6200
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6200
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcaa ucacaaccau acuaacugca guuacuuucu gcuucgcauc cggccaaaac      180

aucaccgaag aguucuacca aucaaccugc uccgcagucu ccaaaggaua ccucggagcc      240

cuucgcaccg gcugguacac cuccgucaua accaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcacagacgc gaaagucaaa cuuaucaaac aagaacucga caaauacaaa      360

aacgccguca ccgaccugca gaugcucaug ugcucaaccc ccgccacagg aagcggcucu      420

gcuaucgcuu ccggcgucgc cgucugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaagucag cccuccucuc caccaacaaa gccgucgucu cucucucaaa cggcguaucc      540

guccucacau ucaaaguccu cgaccucaaa aacuacaucg acaaacaacu ucuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac cccgaaacag ucauggaauu ucaacaaaag      660

aacaaccgcc ucuuagaaau cacccgagaa uuuuccguca acgcgggagu cacaaccccc      720

guuucuacgu auaugcucac caacuccgaa cuccuuuccc ucauaaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgaca acaauccuac      840

ucuauuaugu gcaucaucaa agaagaaguu cucgccuacg ucguccaacu accccucuac      900

ggcgugaucg acacccccug cuggaaacua cacaccucac cccucugcac caccaacacc      960

aaggaaggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcu     1020

ggcuccgucu cauucuuccc gcaagccgaa acuugcaaag uaugcuccaa cagaguauuc     1080

ugcgacacca ugaacucacu aacccucccu uccgaaguca accuuugcaa cguugacaua     1140

uucaacccaa aguacgauug caaaauuaug acauccaaaa cagaugucuc cuccuccguc     1200

aucacauccc ucggugccau uguaucaugc uacggaaaaa ccaaaugcac cgcauccaac     1260

aaaaacaaag gaaucaucaa aaccuucuca aacggcugcg auuacgucuc aaacaaagga     1320

gucgacacag ucuccgucgg aaacacccua uacuacguca acaaacaaga aggccaaucc     1380

cuguacguca aaggagaacc caucaucaac uucuacgacc cccucgucuu cccgagcgac     1440

gaguucgacg ccuccaucuc acaagucaau gaaaagauca accaaucccu ugccuucauc     1500

cggaaaucgg acgaacuccu acacaacgug aacgcuggaa aaucaaccac caacaucaug     1560

aucacaacca ucauuaucgu caucaucguc auacuccucu cccuaaucgc cgucggccuc     1620

cuccuguauu gcaaagcucg cuccaccccc gucacccugu ccaaagacca acucuccgga     1680

aucaacaaca ucgccuucuc aaacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6201
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6201
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6202
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6202
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcuccacccc cgugacccug agcaaggacc agcuguccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6203
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6203
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6204
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6204
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggucaacacc ugugaccuug aguaaggauc agcugucugg gauuaacaau     1680

aucgcuuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6205
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6205
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6206
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6206
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcagcacacc ggugacccug ucuaaggauc agcuuuccgg aauuaacaau     1680

aucgcguuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6207
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6207
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaaucuuaaa agcaaaugcu      120

auaaccacaa uauuaacagc aguaacauuc uguuuugccu ccggacaaaa cauaacagaa      180

gaauuuuauc aaucaacaug cucugcagua uccaaagguu acuuaggcgc acuacgcacu      240

ggaugguaua caucaguaau aacaauagaa cuaucaaaca uaaaagaaaa uaaauguaac      300

gguacugacg caaaagugaa acuaauuaaa caagaacucg acaaauacaa aaaugcugua      360

acagaccuac aaaugcuaau gugcucaaca cccgcaaccg gaucaggauc agccauagcc      420

uccggagucg caguaugcaa aguauuacau cuugaaggag aaguaaauaa aauaaaauca      480

gcauuacuau ccacaaauaa agccguagua ucacuaucaa acgguguauc cguccuuaca      540

uucaaaguau uagaucuaaa aaacuacaua gauaaacaac uacuacccau cuuaaacaaa      600

caaucaugcu caauucccaa cccagaaaca gucauggaau uucaacaaaa aaacaacaga      660

cucuuagaaa uaacacgaga auuuucagua aacgcaggag uaaccacacc aguaaguaca      720

uacaugcuca ccaacucaga auuauuauca cuuauuaacg acaugccaau uacaaacgac      780

caaaaaaaau uaaugucaaa caauguccaa auuguuagac aacaaucaua cucuauaaug      840

uguauaauaa aagaagaagu acuagcuuac guaguucaau uaccacuaua uggcguaaua      900

gauacaccuu gcuggaaacu acauacaucu ccauuaugua caacuaacac aaaagaagga      960

ucuaacauau gccuaacacg cacagaucga ggaugguacu gcgauaaugc agguuccgua     1020

ucauucuuuc cacaagcaga aacauguaaa guaugcucaa acagaguauu cugugacacu     1080

augaacuccu uaacccuacc cucagaaguc aaucuaugca acguugacau auuuaaccca     1140

aaauacgacu guaaaaucau gacaucuaaa acagacguau caucaucagu uauuacaucc     1200

cuaggagcaa uaguaucuug cuacggaaaa acaaaaugua cagcauccaa caaaaacaaa     1260

ggaauaauca aaacauucuc aaacggcugc gacuacguau caaacaaagg uguagacaca     1320

guaucaguag gaaauacuuu auauuacgua aauaaacaag aaggacaauc ucuauacguu     1380

aaaggcgaac cuauuauaaa cuucuacgac ccacucguau ucccuucaga cgaauuugac     1440

gcaucuauau cccaaguuaa cgaaaaaauc aaccaaucau uagccuuuau aagaaaaucc     1500

gacgaauuau uacauaacgu caacgcugga aaaucaacaa cuaacauaau gauaaccaca     1560

auaauaauag ucaucauagu uauauuacua agucuaauag ccguaggccu ccuacuuuau     1620

ugcaaagcaa gaucaacacc aguaacauua uccaaagacc aacucagcgg cauaaacaau     1680

auagcuuuuu caaacuaggg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6208
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6208
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgca      120

aucacaacca uacuaacugc aguuacuuuc ugcuucgcau ccggccaaaa caucaccgaa      180

gaguucuacc aaucaaccug cuccgcaguc uccaaaggau accucggagc ccuucgcacc      240

ggcugguaca ccuccgucau aaccaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcacagacg cgaaagucaa acuuaucaaa caagaacucg acaaauacaa aaacgccguc      360

accgaccugc agaugcucau gugcucaacc cccgccacag gaagcggcuc ugcuaucgcu      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaguca      480

gcccuccucu ccaccaacaa agccgucguc ucucucucaa acggcguauc cguccucaca      540

uucaaagucc ucgaccucaa aaacuacauc gacaaacaac uucuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa ccccgaaaca gucauggaau uucaacaaaa gaacaaccgc      660

cucuuagaaa ucacccgaga auuuuccguc aacgcgggag ucacaacccc cguuucuacg      720

uauaugcuca ccaacuccga acuccuuucc cucauaaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguccaa aucguccgac aacaauccua cucuauuaug      840

ugcaucauca aagaagaagu ucucgccuac gucguccaac uaccccucua cggcgugauc      900

gacacccccu gcuggaaacu acacaccuca ccccucugca ccaccaacac caaggaaggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc uggcuccguc     1020

ucauucuucc cgcaagccga aacuugcaaa guaugcucca acagaguauu cugcgacacc     1080

augaacucac uaacccuccc uuccgaaguc aaccuuugca acguugacau auucaaccca     1140

aaguacgauu gcaaaauuau gacauccaaa acagaugucu ccuccuccgu caucacaucc     1200

cucggugcca uuguaucaug cuacggaaaa accaaaugca ccgcauccaa caaaaacaaa     1260

ggaaucauca aaaccuucuc aaacggcugc gauuacgucu caaacaaagg agucgacaca     1320

gucuccgucg gaaacacccu auacuacguc aacaaacaag aaggccaauc ccuguacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccucgucu ucccgagcga cgaguucgac     1440

gccuccaucu cacaagucaa ugaaaagauc aaccaauccc uugccuucau ccggaaaucg     1500

gacgaacucc uacacaacgu gaacgcugga aaaucaacca ccaacaucau gaucacaacc     1560

aucauuaucg ucaucaucgu cauacuccuc ucccuaaucg ccgucggccu ccuccuguau     1620

ugcaaagcuc gcuccacccc cgucacccug uccaaagacc aacucuccgg aaucaacaac     1680

aucgccuucu caaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6209
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6209
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6210
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6210
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcucca cccccgugac ccugagcaag     1740

gaccagcugu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6211
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6211
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6212
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6212
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggucaa caccugugac cuugaguaag     1740

gaucagcugu cugggauuaa caauaucgcu uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6213
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6213
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6214
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6214
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcagca caccggugac ccugucuaag     1740

gaucagcuuu ccggaauuaa caauaucgcg uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6215
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6215
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaaucu uaaaagcaaa ugcuauaacc acaauauuaa cagcaguaac auucuguuuu      240

gccuccggac aaaacauaac agaagaauuu uaucaaucaa caugcucugc aguauccaaa      300

gguuacuuag gcgcacuacg cacuggaugg uauacaucag uaauaacaau agaacuauca      360

aacauaaaag aaaauaaaug uaacgguacu gacgcaaaag ugaaacuaau uaaacaagaa      420

cucgacaaau acaaaaaugc uguaacagac cuacaaaugc uaaugugcuc aacacccgca      480

accggaucag gaucagccau agccuccgga gucgcaguau gcaaaguauu acaucuugaa      540

ggagaaguaa auaaaauaaa aucagcauua cuauccacaa auaaagccgu aguaucacua      600

ucaaacggug uauccguccu uacauucaaa guauuagauc uaaaaaacua cauagauaaa      660

caacuacuac ccaucuuaaa caaacaauca ugcucaauuc ccaacccaga aacagucaug      720

gaauuucaac aaaaaaacaa cagacucuua gaaauaacac gagaauuuuc aguaaacgca      780

ggaguaacca caccaguaag uacauacaug cucaccaacu cagaauuauu aucacuuauu      840

aacgacaugc caauuacaaa cgaccaaaaa aaauuaaugu caaacaaugu ccaaauuguu      900

agacaacaau cauacucuau aauguguaua auaaaagaag aaguacuagc uuacguaguu      960

caauuaccac uauauggcgu aauagauaca ccuugcugga aacuacauac aucuccauua     1020

uguacaacua acacaaaaga aggaucuaac auaugccuaa cacgcacaga ucgaggaugg     1080

uacugcgaua augcagguuc cguaucauuc uuuccacaag cagaaacaug uaaaguaugc     1140

ucaaacagag uauucuguga cacuaugaac uccuuaaccc uacccucaga agucaaucua     1200

ugcaacguug acauauuuaa cccaaaauac gacuguaaaa ucaugacauc uaaaacagac     1260

guaucaucau caguuauuac aucccuagga gcaauaguau cuugcuacgg aaaaacaaaa     1320

uguacagcau ccaacaaaaa caaaggaaua aucaaaacau ucucaaacgg cugcgacuac     1380

guaucaaaca aagguguaga cacaguauca guaggaaaua cuuuauauua cguaaauaaa     1440

caagaaggac aaucucuaua cguuaaaggc gaaccuauua uaaacuucua cgacccacuc     1500

guauucccuu cagacgaauu ugacgcaucu auaucccaag uuaacgaaaa aaucaaccaa     1560

ucauuagccu uuauaagaaa auccgacgaa uuauuacaua acgucaacgc uggaaaauca     1620

acaacuaaca uaaugauaac cacaauaaua auagucauca uaguuauauu acuaagucua     1680

auagccguag gccuccuacu uuauugcaaa gcaagaucaa caccaguaac auuauccaaa     1740

gaccaacuca gcggcauaaa caauauagcu uuuucaaacu agggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6216
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6216
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgcaaucaca accauacuaa cugcaguuac uuucugcuuc      240

gcauccggcc aaaacaucac cgaagaguuc uaccaaucaa ccugcuccgc agucuccaaa      300

ggauaccucg gagcccuucg caccggcugg uacaccuccg ucauaaccau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcaca gacgcgaaag ucaaacuuau caaacaagaa      420

cucgacaaau acaaaaacgc cgucaccgac cugcagaugc ucaugugcuc aacccccgcc      480

acaggaagcg gcucugcuau cgcuuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa gucagcccuc cucuccacca acaaagccgu cgucucucuc      600

ucaaacggcg uauccguccu cacauucaaa guccucgacc ucaaaaacua caucgacaaa      660

caacuucucc ccauccuaaa caaacaauca ugcuccaucc ccaaccccga aacagucaug      720

gaauuucaac aaaagaacaa ccgccucuua gaaaucaccc gagaauuuuc cgucaacgcg      780

ggagucacaa cccccguuuc uacguauaug cucaccaacu ccgaacuccu uucccucaua      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu ccaaaucguc      900

cgacaacaau ccuacucuau uaugugcauc aucaaagaag aaguucucgc cuacgucguc      960

caacuacccc ucuacggcgu gaucgacacc cccugcugga aacuacacac cucaccccuc     1020

ugcaccacca acaccaagga aggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgcuggcuc cgucucauuc uucccgcaag ccgaaacuug caaaguaugc     1140

uccaacagag uauucugcga caccaugaac ucacuaaccc ucccuuccga agucaaccuu     1200

ugcaacguug acauauucaa cccaaaguac gauugcaaaa uuaugacauc caaaacagau     1260

gucuccuccu ccgucaucac aucccucggu gccauuguau caugcuacgg aaaaaccaaa     1320

ugcaccgcau ccaacaaaaa caaaggaauc aucaaaaccu ucucaaacgg cugcgauuac     1380

gucucaaaca aaggagucga cacagucucc gucggaaaca cccuauacua cgucaacaaa     1440

caagaaggcc aaucccugua cgucaaagga gaacccauca ucaacuucua cgacccccuc     1500

gucuucccga gcgacgaguu cgacgccucc aucucacaag ucaaugaaaa gaucaaccaa     1560

ucccuugccu ucauccggaa aucggacgaa cuccuacaca acgugaacgc uggaaaauca     1620

accaccaaca ucaugaucac aaccaucauu aucgucauca ucgucauacu ccucucccua     1680

aucgccgucg gccuccuccu guauugcaaa gcucgcucca cccccgucac ccuguccaaa     1740

gaccaacucu ccggaaucaa caacaucgcc uucucaaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6217
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6217
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6218
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6218
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

ccacccccgu gacccugagc aaggaccagc uguccggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6219
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6219
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6220
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6220
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

caacaccugu gaccuugagu aaggaucagc ugucugggau uaacaauauc gcuuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6221
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6221
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6222
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6222
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgca     1620

gcacaccggu gacccugucu aaggaucagc uuuccggaau uaacaauauc gcguucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6223
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6223
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau      120

uaacagcagu aacauucugu uuugccuccg gacaaaacau aacagaagaa uuuuaucaau      180

caacaugcuc ugcaguaucc aaagguuacu uaggcgcacu acgcacugga ugguauacau      240

caguaauaac aauagaacua ucaaacauaa aagaaaauaa auguaacggu acugacgcaa      300

aagugaaacu aauuaaacaa gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa      360

ugcuaaugug cucaacaccc gcaaccggau caggaucagc cauagccucc ggagucgcag      420

uaugcaaagu auuacaucuu gaaggagaag uaaauaaaau aaaaucagca uuacuaucca      480

caaauaaagc cguaguauca cuaucaaacg guguauccgu ccuuacauuc aaaguauuag      540

aucuaaaaaa cuacauagau aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa      600

uucccaaccc agaaacaguc auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa      660

cacgagaauu uucaguaaac gcaggaguaa ccacaccagu aaguacauac augcucacca      720

acucagaauu auuaucacuu auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa      780

ugucaaacaa uguccaaauu guuagacaac aaucauacuc uauaaugugu auaauaaaag      840

aagaaguacu agcuuacgua guucaauuac cacuauaugg cguaauagau acaccuugcu      900

ggaaacuaca uacaucucca uuauguacaa cuaacacaaa agaaggaucu aacauaugcc      960

uaacacgcac agaucgagga ugguacugcg auaaugcagg uuccguauca uucuuuccac     1020

aagcagaaac auguaaagua ugcucaaaca gaguauucug ugacacuaug aacuccuuaa     1080

cccuacccuc agaagucaau cuaugcaacg uugacauauu uaacccaaaa uacgacugua     1140

aaaucaugac aucuaaaaca gacguaucau caucaguuau uacaucccua ggagcaauag     1200

uaucuugcua cggaaaaaca aaauguacag cauccaacaa aaacaaagga auaaucaaaa     1260

cauucucaaa cggcugcgac uacguaucaa acaaaggugu agacacagua ucaguaggaa     1320

auacuuuaua uuacguaaau aaacaagaag gacaaucucu auacguuaaa ggcgaaccua     1380

uuauaaacuu cuacgaccca cucguauucc cuucagacga auuugacgca ucuauauccc     1440

aaguuaacga aaaaaucaac caaucauuag ccuuuauaag aaaauccgac gaauuauuac     1500

auaacgucaa cgcuggaaaa ucaacaacua acauaaugau aaccacaaua auaauaguca     1560

ucauaguuau auuacuaagu cuaauagccg uaggccuccu acuuuauugc aaagcaagau     1620

caacaccagu aacauuaucc aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa     1680

acuagggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6224
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6224
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgcaauc acaaccauac      120

uaacugcagu uacuuucugc uucgcauccg gccaaaacau caccgaagag uucuaccaau      180

caaccugcuc cgcagucucc aaaggauacc ucggagcccu ucgcaccggc ugguacaccu      240

ccgucauaac caucgaacuc ucaaacauaa aagaaaacaa augcaacggc acagacgcga      300

aagucaaacu uaucaaacaa gaacucgaca aauacaaaaa cgccgucacc gaccugcaga      360

ugcucaugug cucaaccccc gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caagucagcc cuccucucca      480

ccaacaaagc cgucgucucu cucucaaacg gcguauccgu ccucacauuc aaaguccucg      540

accucaaaaa cuacaucgac aaacaacuuc uccccauccu aaacaaacaa ucaugcucca      600

uccccaaccc cgaaacaguc auggaauuuc aacaaaagaa caaccgccuc uuagaaauca      660

cccgagaauu uuccgucaac gcgggaguca caacccccgu uucuacguau augcucacca      720

acuccgaacu ccuuucccuc auaaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguccaaauc guccgacaac aauccuacuc uauuaugugc aucaucaaag      840

aagaaguucu cgccuacguc guccaacuac cccucuacgg cgugaucgac acccccugcu      900

ggaaacuaca caccucaccc cucugcacca ccaacaccaa ggaaggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgcugg cuccgucuca uucuucccgc     1020

aagccgaaac uugcaaagua ugcuccaaca gaguauucug cgacaccaug aacucacuaa     1080

cccucccuuc cgaagucaac cuuugcaacg uugacauauu caacccaaag uacgauugca     1140

aaauuaugac auccaaaaca gaugucuccu ccuccgucau cacaucccuc ggugccauug     1200

uaucaugcua cggaaaaacc aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa     1260

ccuucucaaa cggcugcgau uacgucucaa acaaaggagu cgacacaguc uccgucggaa     1320

acacccuaua cuacgucaac aaacaagaag gccaaucccu guacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc cgagcgacga guucgacgcc uccaucucac     1440

aagucaauga aaagaucaac caaucccuug ccuucauccg gaaaucggac gaacuccuac     1500

acaacgugaa cgcuggaaaa ucaaccacca acaucaugau cacaaccauc auuaucguca     1560

ucaucgucau acuccucucc cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu     1620

ccacccccgu cacccugucc aaagaccaac ucuccggaau caacaacauc gccuucucaa     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6225
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6225
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6226
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6226
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcucca cccccgugac ccugagcaag     1740

gaccagcugu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6227
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6227
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6228
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6228
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggucaa caccugugac cuugaguaag     1740

gaucagcugu cugggauuaa caauaucgcu uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6229
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6229
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6230
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6230
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcagca caccggugac ccugucuaag     1740

gaucagcuuu ccggaauuaa caauaucgcg uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6231
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6231
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaaucu uaaaagcaaa ugcuauaacc acaauauuaa cagcaguaac auucuguuuu      240

gccuccggac aaaacauaac agaagaauuu uaucaaucaa caugcucugc aguauccaaa      300

gguuacuuag gcgcacuacg cacuggaugg uauacaucag uaauaacaau agaacuauca      360

aacauaaaag aaaauaaaug uaacgguacu gacgcaaaag ugaaacuaau uaaacaagaa      420

cucgacaaau acaaaaaugc uguaacagac cuacaaaugc uaaugugcuc aacacccgca      480

accggaucag gaucagccau agccuccgga gucgcaguau gcaaaguauu acaucuugaa      540

ggagaaguaa auaaaauaaa aucagcauua cuauccacaa auaaagccgu aguaucacua      600

ucaaacggug uauccguccu uacauucaaa guauuagauc uaaaaaacua cauagauaaa      660

caacuacuac ccaucuuaaa caaacaauca ugcucaauuc ccaacccaga aacagucaug      720

gaauuucaac aaaaaaacaa cagacucuua gaaauaacac gagaauuuuc aguaaacgca      780

ggaguaacca caccaguaag uacauacaug cucaccaacu cagaauuauu aucacuuauu      840

aacgacaugc caauuacaaa cgaccaaaaa aaauuaaugu caaacaaugu ccaaauuguu      900

agacaacaau cauacucuau aauguguaua auaaaagaag aaguacuagc uuacguaguu      960

caauuaccac uauauggcgu aauagauaca ccuugcugga aacuacauac aucuccauua     1020

uguacaacua acacaaaaga aggaucuaac auaugccuaa cacgcacaga ucgaggaugg     1080

uacugcgaua augcagguuc cguaucauuc uuuccacaag cagaaacaug uaaaguaugc     1140

ucaaacagag uauucuguga cacuaugaac uccuuaaccc uacccucaga agucaaucua     1200

ugcaacguug acauauuuaa cccaaaauac gacuguaaaa ucaugacauc uaaaacagac     1260

guaucaucau caguuauuac aucccuagga gcaauaguau cuugcuacgg aaaaacaaaa     1320

uguacagcau ccaacaaaaa caaaggaaua aucaaaacau ucucaaacgg cugcgacuac     1380

guaucaaaca aagguguaga cacaguauca guaggaaaua cuuuauauua cguaaauaaa     1440

caagaaggac aaucucuaua cguuaaaggc gaaccuauua uaaacuucua cgacccacuc     1500

guauucccuu cagacgaauu ugacgcaucu auaucccaag uuaacgaaaa aaucaaccaa     1560

ucauuagccu uuauaagaaa auccgacgaa uuauuacaua acgucaacgc uggaaaauca     1620

acaacuaaca uaaugauaac cacaauaaua auagucauca uaguuauauu acuaagucua     1680

auagccguag gccuccuacu uuauugcaaa gcaagaucaa caccaguaac auuauccaaa     1740

gaccaacuca gcggcauaaa caauauagcu uuuucaaacu agggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6232
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6232
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgcaaucaca accauacuaa cugcaguuac uuucugcuuc      240

gcauccggcc aaaacaucac cgaagaguuc uaccaaucaa ccugcuccgc agucuccaaa      300

ggauaccucg gagcccuucg caccggcugg uacaccuccg ucauaaccau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcaca gacgcgaaag ucaaacuuau caaacaagaa      420

cucgacaaau acaaaaacgc cgucaccgac cugcagaugc ucaugugcuc aacccccgcc      480

acaggaagcg gcucugcuau cgcuuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa gucagcccuc cucuccacca acaaagccgu cgucucucuc      600

ucaaacggcg uauccguccu cacauucaaa guccucgacc ucaaaaacua caucgacaaa      660

caacuucucc ccauccuaaa caaacaauca ugcuccaucc ccaaccccga aacagucaug      720

gaauuucaac aaaagaacaa ccgccucuua gaaaucaccc gagaauuuuc cgucaacgcg      780

ggagucacaa cccccguuuc uacguauaug cucaccaacu ccgaacuccu uucccucaua      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu ccaaaucguc      900

cgacaacaau ccuacucuau uaugugcauc aucaaagaag aaguucucgc cuacgucguc      960

caacuacccc ucuacggcgu gaucgacacc cccugcugga aacuacacac cucaccccuc     1020

ugcaccacca acaccaagga aggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgcuggcuc cgucucauuc uucccgcaag ccgaaacuug caaaguaugc     1140

uccaacagag uauucugcga caccaugaac ucacuaaccc ucccuuccga agucaaccuu     1200

ugcaacguug acauauucaa cccaaaguac gauugcaaaa uuaugacauc caaaacagau     1260

gucuccuccu ccgucaucac aucccucggu gccauuguau caugcuacgg aaaaaccaaa     1320

ugcaccgcau ccaacaaaaa caaaggaauc aucaaaaccu ucucaaacgg cugcgauuac     1380

gucucaaaca aaggagucga cacagucucc gucggaaaca cccuauacua cgucaacaaa     1440

caagaaggcc aaucccugua cgucaaagga gaacccauca ucaacuucua cgacccccuc     1500

gucuucccga gcgacgaguu cgacgccucc aucucacaag ucaaugaaaa gaucaaccaa     1560

ucccuugccu ucauccggaa aucggacgaa cuccuacaca acgugaacgc uggaaaauca     1620

accaccaaca ucaugaucac aaccaucauu aucgucauca ucgucauacu ccucucccua     1680

aucgccgucg gccuccuccu guauugcaaa gcucgcucca cccccgucac ccuguccaaa     1740

gaccaacucu ccggaaucaa caacaucgcc uucucaaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6233
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6233
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6234
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6234
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      420

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      480

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      540

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      600

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc     1020

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1080

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1140

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1620

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu ccacccccgu gacccugagc     1680

aaggaccagc uguccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6235
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6235
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      660

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6236
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6236
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      420

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      480

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      540

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      600

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      660

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      720

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      780

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      840

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua      900

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu      960

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg     1020

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1080

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1140

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1200

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1260

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1320

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1380

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1440

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1500

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1560

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1620

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu caacaccugu gaccuugagu     1680

aaggaucagc ugucugggau uaacaauauc gcuuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6237
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6237
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      660

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6238
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6238
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      420

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      480

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      540

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      600

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      660

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      720

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      780

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      840

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug      900

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu      960

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc     1020

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1080

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1140

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1200

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1260

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1320

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1380

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1440

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1500

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1560

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1620

cuuaucgccg uggggcugcu ccuguacugc aaagcucgca gcacaccggu gacccugucu     1680

aaggaucagc uuuccggaau uaacaauauc gcguucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6239
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6239
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau uaacagcagu aacauucugu      180

uuugccuccg gacaaaacau aacagaagaa uuuuaucaau caacaugcuc ugcaguaucc      240

aaagguuacu uaggcgcacu acgcacugga ugguauacau caguaauaac aauagaacua      300

ucaaacauaa aagaaaauaa auguaacggu acugacgcaa aagugaaacu aauuaaacaa      360

gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa ugcuaaugug cucaacaccc      420

gcaaccggau caggaucagc cauagccucc ggagucgcag uaugcaaagu auuacaucuu      480

gaaggagaag uaaauaaaau aaaaucagca uuacuaucca caaauaaagc cguaguauca      540

cuaucaaacg guguauccgu ccuuacauuc aaaguauuag aucuaaaaaa cuacauagau      600

aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa uucccaaccc agaaacaguc      660

auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa cacgagaauu uucaguaaac      720

gcaggaguaa ccacaccagu aaguacauac augcucacca acucagaauu auuaucacuu      780

auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa ugucaaacaa uguccaaauu      840

guuagacaac aaucauacuc uauaaugugu auaauaaaag aagaaguacu agcuuacgua      900

guucaauuac cacuauaugg cguaauagau acaccuugcu ggaaacuaca uacaucucca      960

uuauguacaa cuaacacaaa agaaggaucu aacauaugcc uaacacgcac agaucgagga     1020

ugguacugcg auaaugcagg uuccguauca uucuuuccac aagcagaaac auguaaagua     1080

ugcucaaaca gaguauucug ugacacuaug aacuccuuaa cccuacccuc agaagucaau     1140

cuaugcaacg uugacauauu uaacccaaaa uacgacugua aaaucaugac aucuaaaaca     1200

gacguaucau caucaguuau uacaucccua ggagcaauag uaucuugcua cggaaaaaca     1260

aaauguacag cauccaacaa aaacaaagga auaaucaaaa cauucucaaa cggcugcgac     1320

uacguaucaa acaaaggugu agacacagua ucaguaggaa auacuuuaua uuacguaaau     1380

aaacaagaag gacaaucucu auacguuaaa ggcgaaccua uuauaaacuu cuacgaccca     1440

cucguauucc cuucagacga auuugacgca ucuauauccc aaguuaacga aaaaaucaac     1500

caaucauuag ccuuuauaag aaaauccgac gaauuauuac auaacgucaa cgcuggaaaa     1560

ucaacaacua acauaaugau aaccacaaua auaauaguca ucauaguuau auuacuaagu     1620

cuaauagccg uaggccuccu acuuuauugc aaagcaagau caacaccagu aacauuaucc     1680

aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa acuagggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6240
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6240
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccucaaagc caacgcaauc acaaccauac uaacugcagu uacuuucugc      180

uucgcauccg gccaaaacau caccgaagag uucuaccaau caaccugcuc cgcagucucc      240

aaaggauacc ucggagcccu ucgcaccggc ugguacaccu ccgucauaac caucgaacuc      300

ucaaacauaa aagaaaacaa augcaacggc acagacgcga aagucaaacu uaucaaacaa      360

gaacucgaca aauacaaaaa cgccgucacc gaccugcaga ugcucaugug cucaaccccc      420

gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg ucugcaaagu ccuccaccuc      480

gaaggcgaag uaaacaaaau caagucagcc cuccucucca ccaacaaagc cgucgucucu      540

cucucaaacg gcguauccgu ccucacauuc aaaguccucg accucaaaaa cuacaucgac      600

aaacaacuuc uccccauccu aaacaaacaa ucaugcucca uccccaaccc cgaaacaguc      660

auggaauuuc aacaaaagaa caaccgccuc uuagaaauca cccgagaauu uuccgucaac      720

gcgggaguca caacccccgu uucuacguau augcucacca acuccgaacu ccuuucccuc      780

auaaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      840

guccgacaac aauccuacuc uauuaugugc aucaucaaag aagaaguucu cgccuacguc      900

guccaacuac cccucuacgg cgugaucgac acccccugcu ggaaacuaca caccucaccc      960

cucugcacca ccaacaccaa ggaaggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgcugg cuccgucuca uucuucccgc aagccgaaac uugcaaagua     1080

ugcuccaaca gaguauucug cgacaccaug aacucacuaa cccucccuuc cgaagucaac     1140

cuuugcaacg uugacauauu caacccaaag uacgauugca aaauuaugac auccaaaaca     1200

gaugucuccu ccuccgucau cacaucccuc ggugccauug uaucaugcua cggaaaaacc     1260

aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa ccuucucaaa cggcugcgau     1320

uacgucucaa acaaaggagu cgacacaguc uccgucggaa acacccuaua cuacgucaac     1380

aaacaagaag gccaaucccu guacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1440

cucgucuucc cgagcgacga guucgacgcc uccaucucac aagucaauga aaagaucaac     1500

caaucccuug ccuucauccg gaaaucggac gaacuccuac acaacgugaa cgcuggaaaa     1560

ucaaccacca acaucaugau cacaaccauc auuaucguca ucaucgucau acuccucucc     1620

cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu ccacccccgu cacccugucc     1680

aaagaccaac ucuccggaau caacaacauc gccuucucaa acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6241
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6241
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6242
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6242
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cuccaccccc gugacccuga gcaaggacca gcuguccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6243
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6243
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6244
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6244
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gucaacaccu gugaccuuga guaaggauca gcugucuggg     1680

auuaacaaua ucgcuuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6245
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6245
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6246
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6246
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cagcacaccg gugacccugu cuaaggauca gcuuuccgga     1680

auuaacaaua ucgcguucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6247
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6247
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aaucuuaaaa      120

gcaaaugcua uaaccacaau auuaacagca guaacauucu guuuugccuc cggacaaaac      180

auaacagaag aauuuuauca aucaacaugc ucugcaguau ccaaagguua cuuaggcgca      240

cuacgcacug gaugguauac aucaguaaua acaauagaac uaucaaacau aaaagaaaau      300

aaauguaacg guacugacgc aaaagugaaa cuaauuaaac aagaacucga caaauacaaa      360

aaugcuguaa cagaccuaca aaugcuaaug ugcucaacac ccgcaaccgg aucaggauca      420

gccauagccu ccggagucgc aguaugcaaa guauuacauc uugaaggaga aguaaauaaa      480

auaaaaucag cauuacuauc cacaaauaaa gccguaguau cacuaucaaa cgguguaucc      540

guccuuacau ucaaaguauu agaucuaaaa aacuacauag auaaacaacu acuacccauc      600

uuaaacaaac aaucaugcuc aauucccaac ccagaaacag ucauggaauu ucaacaaaaa      660

aacaacagac ucuuagaaau aacacgagaa uuuucaguaa acgcaggagu aaccacacca      720

guaaguacau acaugcucac caacucagaa uuauuaucac uuauuaacga caugccaauu      780

acaaacgacc aaaaaaaauu aaugucaaac aauguccaaa uuguuagaca acaaucauac      840

ucuauaaugu guauaauaaa agaagaagua cuagcuuacg uaguucaauu accacuauau      900

ggcguaauag auacaccuug cuggaaacua cauacaucuc cauuauguac aacuaacaca      960

aaagaaggau cuaacauaug ccuaacacgc acagaucgag gaugguacug cgauaaugca     1020

gguuccguau cauucuuucc acaagcagaa acauguaaag uaugcucaaa cagaguauuc     1080

ugugacacua ugaacuccuu aacccuaccc ucagaaguca aucuaugcaa cguugacaua     1140

uuuaacccaa aauacgacug uaaaaucaug acaucuaaaa cagacguauc aucaucaguu     1200

auuacauccc uaggagcaau aguaucuugc uacggaaaaa caaaauguac agcauccaac     1260

aaaaacaaag gaauaaucaa aacauucuca aacggcugcg acuacguauc aaacaaaggu     1320

guagacacag uaucaguagg aaauacuuua uauuacguaa auaaacaaga aggacaaucu     1380

cuauacguua aaggcgaacc uauuauaaac uucuacgacc cacucguauu cccuucagac     1440

gaauuugacg caucuauauc ccaaguuaac gaaaaaauca accaaucauu agccuuuaua     1500

agaaaauccg acgaauuauu acauaacguc aacgcuggaa aaucaacaac uaacauaaug     1560

auaaccacaa uaauaauagu caucauaguu auauuacuaa gucuaauagc cguaggccuc     1620

cuacuuuauu gcaaagcaag aucaacacca guaacauuau ccaaagacca acucagcggc     1680

auaaacaaua uagcuuuuuc aaacuaggga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6248
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6248
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcaa ucacaaccau acuaacugca guuacuuucu gcuucgcauc cggccaaaac      180

aucaccgaag aguucuacca aucaaccugc uccgcagucu ccaaaggaua ccucggagcc      240

cuucgcaccg gcugguacac cuccgucaua accaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcacagacgc gaaagucaaa cuuaucaaac aagaacucga caaauacaaa      360

aacgccguca ccgaccugca gaugcucaug ugcucaaccc ccgccacagg aagcggcucu      420

gcuaucgcuu ccggcgucgc cgucugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaagucag cccuccucuc caccaacaaa gccgucgucu cucucucaaa cggcguaucc      540

guccucacau ucaaaguccu cgaccucaaa aacuacaucg acaaacaacu ucuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac cccgaaacag ucauggaauu ucaacaaaag      660

aacaaccgcc ucuuagaaau cacccgagaa uuuuccguca acgcgggagu cacaaccccc      720

guuucuacgu auaugcucac caacuccgaa cuccuuuccc ucauaaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgaca acaauccuac      840

ucuauuaugu gcaucaucaa agaagaaguu cucgccuacg ucguccaacu accccucuac      900

ggcgugaucg acacccccug cuggaaacua cacaccucac cccucugcac caccaacacc      960

aaggaaggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcu     1020

ggcuccgucu cauucuuccc gcaagccgaa acuugcaaag uaugcuccaa cagaguauuc     1080

ugcgacacca ugaacucacu aacccucccu uccgaaguca accuuugcaa cguugacaua     1140

uucaacccaa aguacgauug caaaauuaug acauccaaaa cagaugucuc cuccuccguc     1200

aucacauccc ucggugccau uguaucaugc uacggaaaaa ccaaaugcac cgcauccaac     1260

aaaaacaaag gaaucaucaa aaccuucuca aacggcugcg auuacgucuc aaacaaagga     1320

gucgacacag ucuccgucgg aaacacccua uacuacguca acaaacaaga aggccaaucc     1380

cuguacguca aaggagaacc caucaucaac uucuacgacc cccucgucuu cccgagcgac     1440

gaguucgacg ccuccaucuc acaagucaau gaaaagauca accaaucccu ugccuucauc     1500

cggaaaucgg acgaacuccu acacaacgug aacgcuggaa aaucaaccac caacaucaug     1560

aucacaacca ucauuaucgu caucaucguc auacuccucu cccuaaucgc cgucggccuc     1620

cuccuguauu gcaaagcucg cuccaccccc gucacccugu ccaaagacca acucuccgga     1680

aucaacaaca ucgccuucuc aaacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6249
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6249
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6250
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6250
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cuccaccccc     1620

gugacccuga gcaaggacca gcuguccggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6251
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6251
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6252
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6252
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gucaacaccu     1620

gugaccuuga guaaggauca gcugucuggg auuaacaaua ucgcuuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6253
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6253
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6254
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6254
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cagcacaccg     1620

gugacccugu cuaaggauca gcuuuccgga auuaacaaua ucgcguucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6255
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6255
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aaucuuaaaa gcaaaugcua uaaccacaau auuaacagca      120

guaacauucu guuuugccuc cggacaaaac auaacagaag aauuuuauca aucaacaugc      180

ucugcaguau ccaaagguua cuuaggcgca cuacgcacug gaugguauac aucaguaaua      240

acaauagaac uaucaaacau aaaagaaaau aaauguaacg guacugacgc aaaagugaaa      300

cuaauuaaac aagaacucga caaauacaaa aaugcuguaa cagaccuaca aaugcuaaug      360

ugcucaacac ccgcaaccgg aucaggauca gccauagccu ccggagucgc aguaugcaaa      420

guauuacauc uugaaggaga aguaaauaaa auaaaaucag cauuacuauc cacaaauaaa      480

gccguaguau cacuaucaaa cgguguaucc guccuuacau ucaaaguauu agaucuaaaa      540

aacuacauag auaaacaacu acuacccauc uuaaacaaac aaucaugcuc aauucccaac      600

ccagaaacag ucauggaauu ucaacaaaaa aacaacagac ucuuagaaau aacacgagaa      660

uuuucaguaa acgcaggagu aaccacacca guaaguacau acaugcucac caacucagaa      720

uuauuaucac uuauuaacga caugccaauu acaaacgacc aaaaaaaauu aaugucaaac      780

aauguccaaa uuguuagaca acaaucauac ucuauaaugu guauaauaaa agaagaagua      840

cuagcuuacg uaguucaauu accacuauau ggcguaauag auacaccuug cuggaaacua      900

cauacaucuc cauuauguac aacuaacaca aaagaaggau cuaacauaug ccuaacacgc      960

acagaucgag gaugguacug cgauaaugca gguuccguau cauucuuucc acaagcagaa     1020

acauguaaag uaugcucaaa cagaguauuc ugugacacua ugaacuccuu aacccuaccc     1080

ucagaaguca aucuaugcaa cguugacaua uuuaacccaa aauacgacug uaaaaucaug     1140

acaucuaaaa cagacguauc aucaucaguu auuacauccc uaggagcaau aguaucuugc     1200

uacggaaaaa caaaauguac agcauccaac aaaaacaaag gaauaaucaa aacauucuca     1260

aacggcugcg acuacguauc aaacaaaggu guagacacag uaucaguagg aaauacuuua     1320

uauuacguaa auaaacaaga aggacaaucu cuauacguua aaggcgaacc uauuauaaac     1380

uucuacgacc cacucguauu cccuucagac gaauuugacg caucuauauc ccaaguuaac     1440

gaaaaaauca accaaucauu agccuuuaua agaaaauccg acgaauuauu acauaacguc     1500

aacgcuggaa aaucaacaac uaacauaaug auaaccacaa uaauaauagu caucauaguu     1560

auauuacuaa gucuaauagc cguaggccuc cuacuuuauu gcaaagcaag aucaacacca     1620

guaacauuau ccaaagacca acucagcggc auaaacaaua uagcuuuuuc aaacuaggga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6256
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6256
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcaa ucacaaccau acuaacugca      120

guuacuuucu gcuucgcauc cggccaaaac aucaccgaag aguucuacca aucaaccugc      180

uccgcagucu ccaaaggaua ccucggagcc cuucgcaccg gcugguacac cuccgucaua      240

accaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcacagacgc gaaagucaaa      300

cuuaucaaac aagaacucga caaauacaaa aacgccguca ccgaccugca gaugcucaug      360

ugcucaaccc ccgccacagg aagcggcucu gcuaucgcuu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaagucag cccuccucuc caccaacaaa      480

gccgucgucu cucucucaaa cggcguaucc guccucacau ucaaaguccu cgaccucaaa      540

aacuacaucg acaaacaacu ucuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

cccgaaacag ucauggaauu ucaacaaaag aacaaccgcc ucuuagaaau cacccgagaa      660

uuuuccguca acgcgggagu cacaaccccc guuucuacgu auaugcucac caacuccgaa      720

cuccuuuccc ucauaaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguccaaa ucguccgaca acaauccuac ucuauuaugu gcaucaucaa agaagaaguu      840

cucgccuacg ucguccaacu accccucuac ggcgugaucg acacccccug cuggaaacua      900

cacaccucac cccucugcac caccaacacc aaggaaggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcu ggcuccgucu cauucuuccc gcaagccgaa     1020

acuugcaaag uaugcuccaa cagaguauuc ugcgacacca ugaacucacu aacccucccu     1080

uccgaaguca accuuugcaa cguugacaua uucaacccaa aguacgauug caaaauuaug     1140

acauccaaaa cagaugucuc cuccuccguc aucacauccc ucggugccau uguaucaugc     1200

uacggaaaaa ccaaaugcac cgcauccaac aaaaacaaag gaaucaucaa aaccuucuca     1260

aacggcugcg auuacgucuc aaacaaagga gucgacacag ucuccgucgg aaacacccua     1320

uacuacguca acaaacaaga aggccaaucc cuguacguca aaggagaacc caucaucaac     1380

uucuacgacc cccucgucuu cccgagcgac gaguucgacg ccuccaucuc acaagucaau     1440

gaaaagauca accaaucccu ugccuucauc cggaaaucgg acgaacuccu acacaacgug     1500

aacgcuggaa aaucaaccac caacaucaug aucacaacca ucauuaucgu caucaucguc     1560

auacuccucu cccuaaucgc cgucggccuc cuccuguauu gcaaagcucg cuccaccccc     1620

gucacccugu ccaaagacca acucuccgga aucaacaaca ucgccuucuc aaacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6257
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6257
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6258
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6258
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcuccac ccccgugacc     1680

cugagcaagg accagcuguc cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6259
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6259
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6260
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6260
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggucaac accugugacc     1680

uugaguaagg aucagcuguc ugggauuaac aauaucgcuu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6261
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6261
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6262
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6262
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcagcac accggugacc     1680

cugucuaagg aucagcuuuc cggaauuaac aauaucgcgu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6263
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6263
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaaucuu aaaagcaaau gcuauaacca caauauuaac agcaguaaca      180

uucuguuuug ccuccggaca aaacauaaca gaagaauuuu aucaaucaac augcucugca      240

guauccaaag guuacuuagg cgcacuacgc acuggauggu auacaucagu aauaacaaua      300

gaacuaucaa acauaaaaga aaauaaaugu aacgguacug acgcaaaagu gaaacuaauu      360

aaacaagaac ucgacaaaua caaaaaugcu guaacagacc uacaaaugcu aaugugcuca      420

acacccgcaa ccggaucagg aucagccaua gccuccggag ucgcaguaug caaaguauua      480

caucuugaag gagaaguaaa uaaaauaaaa ucagcauuac uauccacaaa uaaagccgua      540

guaucacuau caaacggugu auccguccuu acauucaaag uauuagaucu aaaaaacuac      600

auagauaaac aacuacuacc caucuuaaac aaacaaucau gcucaauucc caacccagaa      660

acagucaugg aauuucaaca aaaaaacaac agacucuuag aaauaacacg agaauuuuca      720

guaaacgcag gaguaaccac accaguaagu acauacaugc ucaccaacuc agaauuauua      780

ucacuuauua acgacaugcc aauuacaaac gaccaaaaaa aauuaauguc aaacaauguc      840

caaauuguua gacaacaauc auacucuaua auguguauaa uaaaagaaga aguacuagcu      900

uacguaguuc aauuaccacu auauggcgua auagauacac cuugcuggaa acuacauaca      960

ucuccauuau guacaacuaa cacaaaagaa ggaucuaaca uaugccuaac acgcacagau     1020

cgaggauggu acugcgauaa ugcagguucc guaucauucu uuccacaagc agaaacaugu     1080

aaaguaugcu caaacagagu auucugugac acuaugaacu ccuuaacccu acccucagaa     1140

gucaaucuau gcaacguuga cauauuuaac ccaaaauacg acuguaaaau caugacaucu     1200

aaaacagacg uaucaucauc aguuauuaca ucccuaggag caauaguauc uugcuacgga     1260

aaaacaaaau guacagcauc caacaaaaac aaaggaauaa ucaaaacauu cucaaacggc     1320

ugcgacuacg uaucaaacaa agguguagac acaguaucag uaggaaauac uuuauauuac     1380

guaaauaaac aagaaggaca aucucuauac guuaaaggcg aaccuauuau aaacuucuac     1440

gacccacucg uauucccuuc agacgaauuu gacgcaucua uaucccaagu uaacgaaaaa     1500

aucaaccaau cauuagccuu uauaagaaaa uccgacgaau uauuacauaa cgucaacgcu     1560

ggaaaaucaa caacuaacau aaugauaacc acaauaauaa uagucaucau aguuauauua     1620

cuaagucuaa uagccguagg ccuccuacuu uauugcaaag caagaucaac accaguaaca     1680

uuauccaaag accaacucag cggcauaaac aauauagcuu uuucaaacua gggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6264
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6264
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gcaaucacaa ccauacuaac ugcaguuacu      180

uucugcuucg cauccggcca aaacaucacc gaagaguucu accaaucaac cugcuccgca      240

gucuccaaag gauaccucgg agcccuucgc accggcuggu acaccuccgu cauaaccauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcacag acgcgaaagu caaacuuauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucaccgacc ugcagaugcu caugugcuca      420

acccccgcca caggaagcgg cucugcuauc gcuuccggcg ucgccgucug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaag ucagcccucc ucuccaccaa caaagccguc      540

gucucucucu caaacggcgu auccguccuc acauucaaag uccucgaccu caaaaacuac      600

aucgacaaac aacuucuccc cauccuaaac aaacaaucau gcuccauccc caaccccgaa      660

acagucaugg aauuucaaca aaagaacaac cgccucuuag aaaucacccg agaauuuucc      720

gucaacgcgg gagucacaac ccccguuucu acguauaugc ucaccaacuc cgaacuccuu      780

ucccucauaa acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacguc      840

caaaucgucc gacaacaauc cuacucuauu augugcauca ucaaagaaga aguucucgcc      900

uacgucgucc aacuaccccu cuacggcgug aucgacaccc ccugcuggaa acuacacacc      960

ucaccccucu gcaccaccaa caccaaggaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgcuggcucc gucucauucu ucccgcaagc cgaaacuugc     1080

aaaguaugcu ccaacagagu auucugcgac accaugaacu cacuaacccu cccuuccgaa     1140

gucaaccuuu gcaacguuga cauauucaac ccaaaguacg auugcaaaau uaugacaucc     1200

aaaacagaug ucuccuccuc cgucaucaca ucccucggug ccauuguauc augcuacgga     1260

aaaaccaaau gcaccgcauc caacaaaaac aaaggaauca ucaaaaccuu cucaaacggc     1320

ugcgauuacg ucucaaacaa aggagucgac acagucuccg ucggaaacac ccuauacuac     1380

gucaacaaac aagaaggcca aucccuguac gucaaaggag aacccaucau caacuucuac     1440

gacccccucg ucuucccgag cgacgaguuc gacgccucca ucucacaagu caaugaaaag     1500

aucaaccaau cccuugccuu cauccggaaa ucggacgaac uccuacacaa cgugaacgcu     1560

ggaaaaucaa ccaccaacau caugaucaca accaucauua ucgucaucau cgucauacuc     1620

cucucccuaa ucgccgucgg ccuccuccug uauugcaaag cucgcuccac ccccgucacc     1680

cuguccaaag accaacucuc cggaaucaac aacaucgccu ucucaaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6265
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6265
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6266
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6266
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcuccacccc cgugacccug agcaaggacc agcuguccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6267
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6267
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6268
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6268
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggucaacacc ugugaccuug aguaaggauc agcugucugg gauuaacaau     1680

aucgcuuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6269
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6269
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6270
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6270
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcagcacacc ggugacccug ucuaaggauc agcuuuccgg aauuaacaau     1680

aucgcguuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6271
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6271
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaaucuuaaa agcaaaugcu      120

auaaccacaa uauuaacagc aguaacauuc uguuuugccu ccggacaaaa cauaacagaa      180

gaauuuuauc aaucaacaug cucugcagua uccaaagguu acuuaggcgc acuacgcacu      240

ggaugguaua caucaguaau aacaauagaa cuaucaaaca uaaaagaaaa uaaauguaac      300

gguacugacg caaaagugaa acuaauuaaa caagaacucg acaaauacaa aaaugcugua      360

acagaccuac aaaugcuaau gugcucaaca cccgcaaccg gaucaggauc agccauagcc      420

uccggagucg caguaugcaa aguauuacau cuugaaggag aaguaaauaa aauaaaauca      480

gcauuacuau ccacaaauaa agccguagua ucacuaucaa acgguguauc cguccuuaca      540

uucaaaguau uagaucuaaa aaacuacaua gauaaacaac uacuacccau cuuaaacaaa      600

caaucaugcu caauucccaa cccagaaaca gucauggaau uucaacaaaa aaacaacaga      660

cucuuagaaa uaacacgaga auuuucagua aacgcaggag uaaccacacc aguaaguaca      720

uacaugcuca ccaacucaga auuauuauca cuuauuaacg acaugccaau uacaaacgac      780

caaaaaaaau uaaugucaaa caauguccaa auuguuagac aacaaucaua cucuauaaug      840

uguauaauaa aagaagaagu acuagcuuac guaguucaau uaccacuaua uggcguaaua      900

gauacaccuu gcuggaaacu acauacaucu ccauuaugua caacuaacac aaaagaagga      960

ucuaacauau gccuaacacg cacagaucga ggaugguacu gcgauaaugc agguuccgua     1020

ucauucuuuc cacaagcaga aacauguaaa guaugcucaa acagaguauu cugugacacu     1080

augaacuccu uaacccuacc cucagaaguc aaucuaugca acguugacau auuuaaccca     1140

aaauacgacu guaaaaucau gacaucuaaa acagacguau caucaucagu uauuacaucc     1200

cuaggagcaa uaguaucuug cuacggaaaa acaaaaugua cagcauccaa caaaaacaaa     1260

ggaauaauca aaacauucuc aaacggcugc gacuacguau caaacaaagg uguagacaca     1320

guaucaguag gaaauacuuu auauuacgua aauaaacaag aaggacaauc ucuauacguu     1380

aaaggcgaac cuauuauaaa cuucuacgac ccacucguau ucccuucaga cgaauuugac     1440

gcaucuauau cccaaguuaa cgaaaaaauc aaccaaucau uagccuuuau aagaaaaucc     1500

gacgaauuau uacauaacgu caacgcugga aaaucaacaa cuaacauaau gauaaccaca     1560

auaauaauag ucaucauagu uauauuacua agucuaauag ccguaggccu ccuacuuuau     1620

ugcaaagcaa gaucaacacc aguaacauua uccaaagacc aacucagcgg cauaaacaau     1680

auagcuuuuu caaacuaggg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6272
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6272
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgca      120

aucacaacca uacuaacugc aguuacuuuc ugcuucgcau ccggccaaaa caucaccgaa      180

gaguucuacc aaucaaccug cuccgcaguc uccaaaggau accucggagc ccuucgcacc      240

ggcugguaca ccuccgucau aaccaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcacagacg cgaaagucaa acuuaucaaa caagaacucg acaaauacaa aaacgccguc      360

accgaccugc agaugcucau gugcucaacc cccgccacag gaagcggcuc ugcuaucgcu      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaguca      480

gcccuccucu ccaccaacaa agccgucguc ucucucucaa acggcguauc cguccucaca      540

uucaaagucc ucgaccucaa aaacuacauc gacaaacaac uucuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa ccccgaaaca gucauggaau uucaacaaaa gaacaaccgc      660

cucuuagaaa ucacccgaga auuuuccguc aacgcgggag ucacaacccc cguuucuacg      720

uauaugcuca ccaacuccga acuccuuucc cucauaaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguccaa aucguccgac aacaauccua cucuauuaug      840

ugcaucauca aagaagaagu ucucgccuac gucguccaac uaccccucua cggcgugauc      900

gacacccccu gcuggaaacu acacaccuca ccccucugca ccaccaacac caaggaaggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc uggcuccguc     1020

ucauucuucc cgcaagccga aacuugcaaa guaugcucca acagaguauu cugcgacacc     1080

augaacucac uaacccuccc uuccgaaguc aaccuuugca acguugacau auucaaccca     1140

aaguacgauu gcaaaauuau gacauccaaa acagaugucu ccuccuccgu caucacaucc     1200

cucggugcca uuguaucaug cuacggaaaa accaaaugca ccgcauccaa caaaaacaaa     1260

ggaaucauca aaaccuucuc aaacggcugc gauuacgucu caaacaaagg agucgacaca     1320

gucuccgucg gaaacacccu auacuacguc aacaaacaag aaggccaauc ccuguacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccucgucu ucccgagcga cgaguucgac     1440

gccuccaucu cacaagucaa ugaaaagauc aaccaauccc uugccuucau ccggaaaucg     1500

gacgaacucc uacacaacgu gaacgcugga aaaucaacca ccaacaucau gaucacaacc     1560

aucauuaucg ucaucaucgu cauacuccuc ucccuaaucg ccgucggccu ccuccuguau     1620

ugcaaagcuc gcuccacccc cgucacccug uccaaagacc aacucuccgg aaucaacaac     1680

aucgccuucu caaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6273
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6273
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6274
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6274
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcuccacccc cgugacccug agcaaggacc agcuguccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6275
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6275
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6276
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6276
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggucaacacc ugugaccuug aguaaggauc agcugucugg gauuaacaau     1680

aucgcuuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6277
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6277
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6278
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6278
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcagcacacc ggugacccug ucuaaggauc agcuuuccgg aauuaacaau     1680

aucgcguuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6279
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6279
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaaucuuaaa agcaaaugcu      120

auaaccacaa uauuaacagc aguaacauuc uguuuugccu ccggacaaaa cauaacagaa      180

gaauuuuauc aaucaacaug cucugcagua uccaaagguu acuuaggcgc acuacgcacu      240

ggaugguaua caucaguaau aacaauagaa cuaucaaaca uaaaagaaaa uaaauguaac      300

gguacugacg caaaagugaa acuaauuaaa caagaacucg acaaauacaa aaaugcugua      360

acagaccuac aaaugcuaau gugcucaaca cccgcaaccg gaucaggauc agccauagcc      420

uccggagucg caguaugcaa aguauuacau cuugaaggag aaguaaauaa aauaaaauca      480

gcauuacuau ccacaaauaa agccguagua ucacuaucaa acgguguauc cguccuuaca      540

uucaaaguau uagaucuaaa aaacuacaua gauaaacaac uacuacccau cuuaaacaaa      600

caaucaugcu caauucccaa cccagaaaca gucauggaau uucaacaaaa aaacaacaga      660

cucuuagaaa uaacacgaga auuuucagua aacgcaggag uaaccacacc aguaaguaca      720

uacaugcuca ccaacucaga auuauuauca cuuauuaacg acaugccaau uacaaacgac      780

caaaaaaaau uaaugucaaa caauguccaa auuguuagac aacaaucaua cucuauaaug      840

uguauaauaa aagaagaagu acuagcuuac guaguucaau uaccacuaua uggcguaaua      900

gauacaccuu gcuggaaacu acauacaucu ccauuaugua caacuaacac aaaagaagga      960

ucuaacauau gccuaacacg cacagaucga ggaugguacu gcgauaaugc agguuccgua     1020

ucauucuuuc cacaagcaga aacauguaaa guaugcucaa acagaguauu cugugacacu     1080

augaacuccu uaacccuacc cucagaaguc aaucuaugca acguugacau auuuaaccca     1140

aaauacgacu guaaaaucau gacaucuaaa acagacguau caucaucagu uauuacaucc     1200

cuaggagcaa uaguaucuug cuacggaaaa acaaaaugua cagcauccaa caaaaacaaa     1260

ggaauaauca aaacauucuc aaacggcugc gacuacguau caaacaaagg uguagacaca     1320

guaucaguag gaaauacuuu auauuacgua aauaaacaag aaggacaauc ucuauacguu     1380

aaaggcgaac cuauuauaaa cuucuacgac ccacucguau ucccuucaga cgaauuugac     1440

gcaucuauau cccaaguuaa cgaaaaaauc aaccaaucau uagccuuuau aagaaaaucc     1500

gacgaauuau uacauaacgu caacgcugga aaaucaacaa cuaacauaau gauaaccaca     1560

auaauaauag ucaucauagu uauauuacua agucuaauag ccguaggccu ccuacuuuau     1620

ugcaaagcaa gaucaacacc aguaacauua uccaaagacc aacucagcgg cauaaacaau     1680

auagcuuuuu caaacuaggg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6280
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6280
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgca      120

aucacaacca uacuaacugc aguuacuuuc ugcuucgcau ccggccaaaa caucaccgaa      180

gaguucuacc aaucaaccug cuccgcaguc uccaaaggau accucggagc ccuucgcacc      240

ggcugguaca ccuccgucau aaccaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcacagacg cgaaagucaa acuuaucaaa caagaacucg acaaauacaa aaacgccguc      360

accgaccugc agaugcucau gugcucaacc cccgccacag gaagcggcuc ugcuaucgcu      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaguca      480

gcccuccucu ccaccaacaa agccgucguc ucucucucaa acggcguauc cguccucaca      540

uucaaagucc ucgaccucaa aaacuacauc gacaaacaac uucuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa ccccgaaaca gucauggaau uucaacaaaa gaacaaccgc      660

cucuuagaaa ucacccgaga auuuuccguc aacgcgggag ucacaacccc cguuucuacg      720

uauaugcuca ccaacuccga acuccuuucc cucauaaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguccaa aucguccgac aacaauccua cucuauuaug      840

ugcaucauca aagaagaagu ucucgccuac gucguccaac uaccccucua cggcgugauc      900

gacacccccu gcuggaaacu acacaccuca ccccucugca ccaccaacac caaggaaggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc uggcuccguc     1020

ucauucuucc cgcaagccga aacuugcaaa guaugcucca acagaguauu cugcgacacc     1080

augaacucac uaacccuccc uuccgaaguc aaccuuugca acguugacau auucaaccca     1140

aaguacgauu gcaaaauuau gacauccaaa acagaugucu ccuccuccgu caucacaucc     1200

cucggugcca uuguaucaug cuacggaaaa accaaaugca ccgcauccaa caaaaacaaa     1260

ggaaucauca aaaccuucuc aaacggcugc gauuacgucu caaacaaagg agucgacaca     1320

gucuccgucg gaaacacccu auacuacguc aacaaacaag aaggccaauc ccuguacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccucgucu ucccgagcga cgaguucgac     1440

gccuccaucu cacaagucaa ugaaaagauc aaccaauccc uugccuucau ccggaaaucg     1500

gacgaacucc uacacaacgu gaacgcugga aaaucaacca ccaacaucau gaucacaacc     1560

aucauuaucg ucaucaucgu cauacuccuc ucccuaaucg ccgucggccu ccuccuguau     1620

ugcaaagcuc gcuccacccc cgucacccug uccaaagacc aacucuccgg aaucaacaac     1680

aucgccuucu caaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  6281
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6281
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6282
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6282
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcuccacccc cgugacccug agcaaggacc agcuguccgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6283
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6283
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6284
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6284
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggucaacacc ugugaccuug aguaaggauc agcugucugg gauuaacaau     1680

aucgcuuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6285
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6285
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6286
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6286
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcagcacacc ggugacccug ucuaaggauc agcuuuccgg aauuaacaau     1680

aucgcguuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6287
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6287
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaaucuuaaa agcaaaugcu      120

auaaccacaa uauuaacagc aguaacauuc uguuuugccu ccggacaaaa cauaacagaa      180

gaauuuuauc aaucaacaug cucugcagua uccaaagguu acuuaggcgc acuacgcacu      240

ggaugguaua caucaguaau aacaauagaa cuaucaaaca uaaaagaaaa uaaauguaac      300

gguacugacg caaaagugaa acuaauuaaa caagaacucg acaaauacaa aaaugcugua      360

acagaccuac aaaugcuaau gugcucaaca cccgcaaccg gaucaggauc agccauagcc      420

uccggagucg caguaugcaa aguauuacau cuugaaggag aaguaaauaa aauaaaauca      480

gcauuacuau ccacaaauaa agccguagua ucacuaucaa acgguguauc cguccuuaca      540

uucaaaguau uagaucuaaa aaacuacaua gauaaacaac uacuacccau cuuaaacaaa      600

caaucaugcu caauucccaa cccagaaaca gucauggaau uucaacaaaa aaacaacaga      660

cucuuagaaa uaacacgaga auuuucagua aacgcaggag uaaccacacc aguaaguaca      720

uacaugcuca ccaacucaga auuauuauca cuuauuaacg acaugccaau uacaaacgac      780

caaaaaaaau uaaugucaaa caauguccaa auuguuagac aacaaucaua cucuauaaug      840

uguauaauaa aagaagaagu acuagcuuac guaguucaau uaccacuaua uggcguaaua      900

gauacaccuu gcuggaaacu acauacaucu ccauuaugua caacuaacac aaaagaagga      960

ucuaacauau gccuaacacg cacagaucga ggaugguacu gcgauaaugc agguuccgua     1020

ucauucuuuc cacaagcaga aacauguaaa guaugcucaa acagaguauu cugugacacu     1080

augaacuccu uaacccuacc cucagaaguc aaucuaugca acguugacau auuuaaccca     1140

aaauacgacu guaaaaucau gacaucuaaa acagacguau caucaucagu uauuacaucc     1200

cuaggagcaa uaguaucuug cuacggaaaa acaaaaugua cagcauccaa caaaaacaaa     1260

ggaauaauca aaacauucuc aaacggcugc gacuacguau caaacaaagg uguagacaca     1320

guaucaguag gaaauacuuu auauuacgua aauaaacaag aaggacaauc ucuauacguu     1380

aaaggcgaac cuauuauaaa cuucuacgac ccacucguau ucccuucaga cgaauuugac     1440

gcaucuauau cccaaguuaa cgaaaaaauc aaccaaucau uagccuuuau aagaaaaucc     1500

gacgaauuau uacauaacgu caacgcugga aaaucaacaa cuaacauaau gauaaccaca     1560

auaauaauag ucaucauagu uauauuacua agucuaauag ccguaggccu ccuacuuuau     1620

ugcaaagcaa gaucaacacc aguaacauua uccaaagacc aacucagcgg cauaaacaau     1680

auagcuuuuu caaacuaggg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6288
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6288
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgca      120

aucacaacca uacuaacugc aguuacuuuc ugcuucgcau ccggccaaaa caucaccgaa      180

gaguucuacc aaucaaccug cuccgcaguc uccaaaggau accucggagc ccuucgcacc      240

ggcugguaca ccuccgucau aaccaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcacagacg cgaaagucaa acuuaucaaa caagaacucg acaaauacaa aaacgccguc      360

accgaccugc agaugcucau gugcucaacc cccgccacag gaagcggcuc ugcuaucgcu      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaguca      480

gcccuccucu ccaccaacaa agccgucguc ucucucucaa acggcguauc cguccucaca      540

uucaaagucc ucgaccucaa aaacuacauc gacaaacaac uucuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa ccccgaaaca gucauggaau uucaacaaaa gaacaaccgc      660

cucuuagaaa ucacccgaga auuuuccguc aacgcgggag ucacaacccc cguuucuacg      720

uauaugcuca ccaacuccga acuccuuucc cucauaaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguccaa aucguccgac aacaauccua cucuauuaug      840

ugcaucauca aagaagaagu ucucgccuac gucguccaac uaccccucua cggcgugauc      900

gacacccccu gcuggaaacu acacaccuca ccccucugca ccaccaacac caaggaaggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc uggcuccguc     1020

ucauucuucc cgcaagccga aacuugcaaa guaugcucca acagaguauu cugcgacacc     1080

augaacucac uaacccuccc uuccgaaguc aaccuuugca acguugacau auucaaccca     1140

aaguacgauu gcaaaauuau gacauccaaa acagaugucu ccuccuccgu caucacaucc     1200

cucggugcca uuguaucaug cuacggaaaa accaaaugca ccgcauccaa caaaaacaaa     1260

ggaaucauca aaaccuucuc aaacggcugc gauuacgucu caaacaaagg agucgacaca     1320

gucuccgucg gaaacacccu auacuacguc aacaaacaag aaggccaauc ccuguacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccucgucu ucccgagcga cgaguucgac     1440

gccuccaucu cacaagucaa ugaaaagauc aaccaauccc uugccuucau ccggaaaucg     1500

gacgaacucc uacacaacgu gaacgcugga aaaucaacca ccaacaucau gaucacaacc     1560

aucauuaucg ucaucaucgu cauacuccuc ucccuaaucg ccgucggccu ccuccuguau     1620

ugcaaagcuc gcuccacccc cgucacccug uccaaagacc aacucuccgg aaucaacaac     1680

aucgccuucu caaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  6289
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6289
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6290
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6290
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcuccacccc cgugacccug agcaaggacc agcuguccgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6291
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6291
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6292
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6292
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggucaacacc ugugaccuug aguaaggauc agcugucugg gauuaacaau     1680

aucgcuuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6293
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6293
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6294
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6294
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcagcacacc ggugacccug ucuaaggauc agcuuuccgg aauuaacaau     1680

aucgcguuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6295
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6295
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaaucuuaaa agcaaaugcu      120

auaaccacaa uauuaacagc aguaacauuc uguuuugccu ccggacaaaa cauaacagaa      180

gaauuuuauc aaucaacaug cucugcagua uccaaagguu acuuaggcgc acuacgcacu      240

ggaugguaua caucaguaau aacaauagaa cuaucaaaca uaaaagaaaa uaaauguaac      300

gguacugacg caaaagugaa acuaauuaaa caagaacucg acaaauacaa aaaugcugua      360

acagaccuac aaaugcuaau gugcucaaca cccgcaaccg gaucaggauc agccauagcc      420

uccggagucg caguaugcaa aguauuacau cuugaaggag aaguaaauaa aauaaaauca      480

gcauuacuau ccacaaauaa agccguagua ucacuaucaa acgguguauc cguccuuaca      540

uucaaaguau uagaucuaaa aaacuacaua gauaaacaac uacuacccau cuuaaacaaa      600

caaucaugcu caauucccaa cccagaaaca gucauggaau uucaacaaaa aaacaacaga      660

cucuuagaaa uaacacgaga auuuucagua aacgcaggag uaaccacacc aguaaguaca      720

uacaugcuca ccaacucaga auuauuauca cuuauuaacg acaugccaau uacaaacgac      780

caaaaaaaau uaaugucaaa caauguccaa auuguuagac aacaaucaua cucuauaaug      840

uguauaauaa aagaagaagu acuagcuuac guaguucaau uaccacuaua uggcguaaua      900

gauacaccuu gcuggaaacu acauacaucu ccauuaugua caacuaacac aaaagaagga      960

ucuaacauau gccuaacacg cacagaucga ggaugguacu gcgauaaugc agguuccgua     1020

ucauucuuuc cacaagcaga aacauguaaa guaugcucaa acagaguauu cugugacacu     1080

augaacuccu uaacccuacc cucagaaguc aaucuaugca acguugacau auuuaaccca     1140

aaauacgacu guaaaaucau gacaucuaaa acagacguau caucaucagu uauuacaucc     1200

cuaggagcaa uaguaucuug cuacggaaaa acaaaaugua cagcauccaa caaaaacaaa     1260

ggaauaauca aaacauucuc aaacggcugc gacuacguau caaacaaagg uguagacaca     1320

guaucaguag gaaauacuuu auauuacgua aauaaacaag aaggacaauc ucuauacguu     1380

aaaggcgaac cuauuauaaa cuucuacgac ccacucguau ucccuucaga cgaauuugac     1440

gcaucuauau cccaaguuaa cgaaaaaauc aaccaaucau uagccuuuau aagaaaaucc     1500

gacgaauuau uacauaacgu caacgcugga aaaucaacaa cuaacauaau gauaaccaca     1560

auaauaauag ucaucauagu uauauuacua agucuaauag ccguaggccu ccuacuuuau     1620

ugcaaagcaa gaucaacacc aguaacauua uccaaagacc aacucagcgg cauaaacaau     1680

auagcuuuuu caaacuaggg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6296
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6296
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgca      120

aucacaacca uacuaacugc aguuacuuuc ugcuucgcau ccggccaaaa caucaccgaa      180

gaguucuacc aaucaaccug cuccgcaguc uccaaaggau accucggagc ccuucgcacc      240

ggcugguaca ccuccgucau aaccaucgaa cucucaaaca uaaaagaaaa caaaugcaac      300

ggcacagacg cgaaagucaa acuuaucaaa caagaacucg acaaauacaa aaacgccguc      360

accgaccugc agaugcucau gugcucaacc cccgccacag gaagcggcuc ugcuaucgcu      420

uccggcgucg ccgucugcaa aguccuccac cucgaaggcg aaguaaacaa aaucaaguca      480

gcccuccucu ccaccaacaa agccgucguc ucucucucaa acggcguauc cguccucaca      540

uucaaagucc ucgaccucaa aaacuacauc gacaaacaac uucuccccau ccuaaacaaa      600

caaucaugcu ccauccccaa ccccgaaaca gucauggaau uucaacaaaa gaacaaccgc      660

cucuuagaaa ucacccgaga auuuuccguc aacgcgggag ucacaacccc cguuucuacg      720

uauaugcuca ccaacuccga acuccuuucc cucauaaacg acaugccaau caccaacgac      780

caaaagaaac ucaugucaaa caacguccaa aucguccgac aacaauccua cucuauuaug      840

ugcaucauca aagaagaagu ucucgccuac gucguccaac uaccccucua cggcgugauc      900

gacacccccu gcuggaaacu acacaccuca ccccucugca ccaccaacac caaggaaggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc uggcuccguc     1020

ucauucuucc cgcaagccga aacuugcaaa guaugcucca acagaguauu cugcgacacc     1080

augaacucac uaacccuccc uuccgaaguc aaccuuugca acguugacau auucaaccca     1140

aaguacgauu gcaaaauuau gacauccaaa acagaugucu ccuccuccgu caucacaucc     1200

cucggugcca uuguaucaug cuacggaaaa accaaaugca ccgcauccaa caaaaacaaa     1260

ggaaucauca aaaccuucuc aaacggcugc gauuacgucu caaacaaagg agucgacaca     1320

gucuccgucg gaaacacccu auacuacguc aacaaacaag aaggccaauc ccuguacguc     1380

aaaggagaac ccaucaucaa cuucuacgac ccccucgucu ucccgagcga cgaguucgac     1440

gccuccaucu cacaagucaa ugaaaagauc aaccaauccc uugccuucau ccggaaaucg     1500

gacgaacucc uacacaacgu gaacgcugga aaaucaacca ccaacaucau gaucacaacc     1560

aucauuaucg ucaucaucgu cauacuccuc ucccuaaucg ccgucggccu ccuccuguau     1620

ugcaaagcuc gcuccacccc cgucacccug uccaaagacc aacucuccgg aaucaacaac     1680

aucgccuucu caaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  6297
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6297
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6298
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6298
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

ccacccccgu gacccugagc aaggaccagc uguccggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6299
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6299
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6300
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6300
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

caacaccugu gaccuugagu aaggaucagc ugucugggau uaacaauauc gcuuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6301
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6301
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6302
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6302
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgca     1620

gcacaccggu gacccugucu aaggaucagc uuuccggaau uaacaauauc gcguucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6303
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6303
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau      120

uaacagcagu aacauucugu uuugccuccg gacaaaacau aacagaagaa uuuuaucaau      180

caacaugcuc ugcaguaucc aaagguuacu uaggcgcacu acgcacugga ugguauacau      240

caguaauaac aauagaacua ucaaacauaa aagaaaauaa auguaacggu acugacgcaa      300

aagugaaacu aauuaaacaa gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa      360

ugcuaaugug cucaacaccc gcaaccggau caggaucagc cauagccucc ggagucgcag      420

uaugcaaagu auuacaucuu gaaggagaag uaaauaaaau aaaaucagca uuacuaucca      480

caaauaaagc cguaguauca cuaucaaacg guguauccgu ccuuacauuc aaaguauuag      540

aucuaaaaaa cuacauagau aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa      600

uucccaaccc agaaacaguc auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa      660

cacgagaauu uucaguaaac gcaggaguaa ccacaccagu aaguacauac augcucacca      720

acucagaauu auuaucacuu auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa      780

ugucaaacaa uguccaaauu guuagacaac aaucauacuc uauaaugugu auaauaaaag      840

aagaaguacu agcuuacgua guucaauuac cacuauaugg cguaauagau acaccuugcu      900

ggaaacuaca uacaucucca uuauguacaa cuaacacaaa agaaggaucu aacauaugcc      960

uaacacgcac agaucgagga ugguacugcg auaaugcagg uuccguauca uucuuuccac     1020

aagcagaaac auguaaagua ugcucaaaca gaguauucug ugacacuaug aacuccuuaa     1080

cccuacccuc agaagucaau cuaugcaacg uugacauauu uaacccaaaa uacgacugua     1140

aaaucaugac aucuaaaaca gacguaucau caucaguuau uacaucccua ggagcaauag     1200

uaucuugcua cggaaaaaca aaauguacag cauccaacaa aaacaaagga auaaucaaaa     1260

cauucucaaa cggcugcgac uacguaucaa acaaaggugu agacacagua ucaguaggaa     1320

auacuuuaua uuacguaaau aaacaagaag gacaaucucu auacguuaaa ggcgaaccua     1380

uuauaaacuu cuacgaccca cucguauucc cuucagacga auuugacgca ucuauauccc     1440

aaguuaacga aaaaaucaac caaucauuag ccuuuauaag aaaauccgac gaauuauuac     1500

auaacgucaa cgcuggaaaa ucaacaacua acauaaugau aaccacaaua auaauaguca     1560

ucauaguuau auuacuaagu cuaauagccg uaggccuccu acuuuauugc aaagcaagau     1620

caacaccagu aacauuaucc aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa     1680

acuagggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6304
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6304
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgcaauc acaaccauac      120

uaacugcagu uacuuucugc uucgcauccg gccaaaacau caccgaagag uucuaccaau      180

caaccugcuc cgcagucucc aaaggauacc ucggagcccu ucgcaccggc ugguacaccu      240

ccgucauaac caucgaacuc ucaaacauaa aagaaaacaa augcaacggc acagacgcga      300

aagucaaacu uaucaaacaa gaacucgaca aauacaaaaa cgccgucacc gaccugcaga      360

ugcucaugug cucaaccccc gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caagucagcc cuccucucca      480

ccaacaaagc cgucgucucu cucucaaacg gcguauccgu ccucacauuc aaaguccucg      540

accucaaaaa cuacaucgac aaacaacuuc uccccauccu aaacaaacaa ucaugcucca      600

uccccaaccc cgaaacaguc auggaauuuc aacaaaagaa caaccgccuc uuagaaauca      660

cccgagaauu uuccgucaac gcgggaguca caacccccgu uucuacguau augcucacca      720

acuccgaacu ccuuucccuc auaaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguccaaauc guccgacaac aauccuacuc uauuaugugc aucaucaaag      840

aagaaguucu cgccuacguc guccaacuac cccucuacgg cgugaucgac acccccugcu      900

ggaaacuaca caccucaccc cucugcacca ccaacaccaa ggaaggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgcugg cuccgucuca uucuucccgc     1020

aagccgaaac uugcaaagua ugcuccaaca gaguauucug cgacaccaug aacucacuaa     1080

cccucccuuc cgaagucaac cuuugcaacg uugacauauu caacccaaag uacgauugca     1140

aaauuaugac auccaaaaca gaugucuccu ccuccgucau cacaucccuc ggugccauug     1200

uaucaugcua cggaaaaacc aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa     1260

ccuucucaaa cggcugcgau uacgucucaa acaaaggagu cgacacaguc uccgucggaa     1320

acacccuaua cuacgucaac aaacaagaag gccaaucccu guacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc cgagcgacga guucgacgcc uccaucucac     1440

aagucaauga aaagaucaac caaucccuug ccuucauccg gaaaucggac gaacuccuac     1500

acaacgugaa cgcuggaaaa ucaaccacca acaucaugau cacaaccauc auuaucguca     1560

ucaucgucau acuccucucc cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu     1620

ccacccccgu cacccugucc aaagaccaac ucuccggaau caacaacauc gccuucucaa     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  6305
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6305
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6306
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6306
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

ccacccccgu gacccugagc aaggaccagc uguccggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6307
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6307
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6308
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6308
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

caacaccugu gaccuugagu aaggaucagc ugucugggau uaacaauauc gcuuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6309
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6309
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6310
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6310
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgca     1620

gcacaccggu gacccugucu aaggaucagc uuuccggaau uaacaauauc gcguucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6311
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6311
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau      120

uaacagcagu aacauucugu uuugccuccg gacaaaacau aacagaagaa uuuuaucaau      180

caacaugcuc ugcaguaucc aaagguuacu uaggcgcacu acgcacugga ugguauacau      240

caguaauaac aauagaacua ucaaacauaa aagaaaauaa auguaacggu acugacgcaa      300

aagugaaacu aauuaaacaa gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa      360

ugcuaaugug cucaacaccc gcaaccggau caggaucagc cauagccucc ggagucgcag      420

uaugcaaagu auuacaucuu gaaggagaag uaaauaaaau aaaaucagca uuacuaucca      480

caaauaaagc cguaguauca cuaucaaacg guguauccgu ccuuacauuc aaaguauuag      540

aucuaaaaaa cuacauagau aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa      600

uucccaaccc agaaacaguc auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa      660

cacgagaauu uucaguaaac gcaggaguaa ccacaccagu aaguacauac augcucacca      720

acucagaauu auuaucacuu auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa      780

ugucaaacaa uguccaaauu guuagacaac aaucauacuc uauaaugugu auaauaaaag      840

aagaaguacu agcuuacgua guucaauuac cacuauaugg cguaauagau acaccuugcu      900

ggaaacuaca uacaucucca uuauguacaa cuaacacaaa agaaggaucu aacauaugcc      960

uaacacgcac agaucgagga ugguacugcg auaaugcagg uuccguauca uucuuuccac     1020

aagcagaaac auguaaagua ugcucaaaca gaguauucug ugacacuaug aacuccuuaa     1080

cccuacccuc agaagucaau cuaugcaacg uugacauauu uaacccaaaa uacgacugua     1140

aaaucaugac aucuaaaaca gacguaucau caucaguuau uacaucccua ggagcaauag     1200

uaucuugcua cggaaaaaca aaauguacag cauccaacaa aaacaaagga auaaucaaaa     1260

cauucucaaa cggcugcgac uacguaucaa acaaaggugu agacacagua ucaguaggaa     1320

auacuuuaua uuacguaaau aaacaagaag gacaaucucu auacguuaaa ggcgaaccua     1380

uuauaaacuu cuacgaccca cucguauucc cuucagacga auuugacgca ucuauauccc     1440

aaguuaacga aaaaaucaac caaucauuag ccuuuauaag aaaauccgac gaauuauuac     1500

auaacgucaa cgcuggaaaa ucaacaacua acauaaugau aaccacaaua auaauaguca     1560

ucauaguuau auuacuaagu cuaauagccg uaggccuccu acuuuauugc aaagcaagau     1620

caacaccagu aacauuaucc aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa     1680

acuagggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6312
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6312
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgcaauc acaaccauac      120

uaacugcagu uacuuucugc uucgcauccg gccaaaacau caccgaagag uucuaccaau      180

caaccugcuc cgcagucucc aaaggauacc ucggagcccu ucgcaccggc ugguacaccu      240

ccgucauaac caucgaacuc ucaaacauaa aagaaaacaa augcaacggc acagacgcga      300

aagucaaacu uaucaaacaa gaacucgaca aauacaaaaa cgccgucacc gaccugcaga      360

ugcucaugug cucaaccccc gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg      420

ucugcaaagu ccuccaccuc gaaggcgaag uaaacaaaau caagucagcc cuccucucca      480

ccaacaaagc cgucgucucu cucucaaacg gcguauccgu ccucacauuc aaaguccucg      540

accucaaaaa cuacaucgac aaacaacuuc uccccauccu aaacaaacaa ucaugcucca      600

uccccaaccc cgaaacaguc auggaauuuc aacaaaagaa caaccgccuc uuagaaauca      660

cccgagaauu uuccgucaac gcgggaguca caacccccgu uucuacguau augcucacca      720

acuccgaacu ccuuucccuc auaaacgaca ugccaaucac caacgaccaa aagaaacuca      780

ugucaaacaa cguccaaauc guccgacaac aauccuacuc uauuaugugc aucaucaaag      840

aagaaguucu cgccuacguc guccaacuac cccucuacgg cgugaucgac acccccugcu      900

ggaaacuaca caccucaccc cucugcacca ccaacaccaa ggaaggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgcugg cuccgucuca uucuucccgc     1020

aagccgaaac uugcaaagua ugcuccaaca gaguauucug cgacaccaug aacucacuaa     1080

cccucccuuc cgaagucaac cuuugcaacg uugacauauu caacccaaag uacgauugca     1140

aaauuaugac auccaaaaca gaugucuccu ccuccgucau cacaucccuc ggugccauug     1200

uaucaugcua cggaaaaacc aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa     1260

ccuucucaaa cggcugcgau uacgucucaa acaaaggagu cgacacaguc uccgucggaa     1320

acacccuaua cuacgucaac aaacaagaag gccaaucccu guacgucaaa ggagaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc cgagcgacga guucgacgcc uccaucucac     1440

aagucaauga aaagaucaac caaucccuug ccuucauccg gaaaucggac gaacuccuac     1500

acaacgugaa cgcuggaaaa ucaaccacca acaucaugau cacaaccauc auuaucguca     1560

ucaucgucau acuccucucc cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu     1620

ccacccccgu cacccugucc aaagaccaac ucuccggaau caacaacauc gccuucucaa     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  6313
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6313
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6314
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6314
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cuccaccccc     1620

gugacccuga gcaaggacca gcuguccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6315
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6315
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6316
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6316
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gucaacaccu     1620

gugaccuuga guaaggauca gcugucuggg auuaacaaua ucgcuuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6317
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6317
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6318
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6318
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cagcacaccg     1620

gugacccugu cuaaggauca gcuuuccgga auuaacaaua ucgcguucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6319
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6319
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aaucuuaaaa gcaaaugcua uaaccacaau auuaacagca      120

guaacauucu guuuugccuc cggacaaaac auaacagaag aauuuuauca aucaacaugc      180

ucugcaguau ccaaagguua cuuaggcgca cuacgcacug gaugguauac aucaguaaua      240

acaauagaac uaucaaacau aaaagaaaau aaauguaacg guacugacgc aaaagugaaa      300

cuaauuaaac aagaacucga caaauacaaa aaugcuguaa cagaccuaca aaugcuaaug      360

ugcucaacac ccgcaaccgg aucaggauca gccauagccu ccggagucgc aguaugcaaa      420

guauuacauc uugaaggaga aguaaauaaa auaaaaucag cauuacuauc cacaaauaaa      480

gccguaguau cacuaucaaa cgguguaucc guccuuacau ucaaaguauu agaucuaaaa      540

aacuacauag auaaacaacu acuacccauc uuaaacaaac aaucaugcuc aauucccaac      600

ccagaaacag ucauggaauu ucaacaaaaa aacaacagac ucuuagaaau aacacgagaa      660

uuuucaguaa acgcaggagu aaccacacca guaaguacau acaugcucac caacucagaa      720

uuauuaucac uuauuaacga caugccaauu acaaacgacc aaaaaaaauu aaugucaaac      780

aauguccaaa uuguuagaca acaaucauac ucuauaaugu guauaauaaa agaagaagua      840

cuagcuuacg uaguucaauu accacuauau ggcguaauag auacaccuug cuggaaacua      900

cauacaucuc cauuauguac aacuaacaca aaagaaggau cuaacauaug ccuaacacgc      960

acagaucgag gaugguacug cgauaaugca gguuccguau cauucuuucc acaagcagaa     1020

acauguaaag uaugcucaaa cagaguauuc ugugacacua ugaacuccuu aacccuaccc     1080

ucagaaguca aucuaugcaa cguugacaua uuuaacccaa aauacgacug uaaaaucaug     1140

acaucuaaaa cagacguauc aucaucaguu auuacauccc uaggagcaau aguaucuugc     1200

uacggaaaaa caaaauguac agcauccaac aaaaacaaag gaauaaucaa aacauucuca     1260

aacggcugcg acuacguauc aaacaaaggu guagacacag uaucaguagg aaauacuuua     1320

uauuacguaa auaaacaaga aggacaaucu cuauacguua aaggcgaacc uauuauaaac     1380

uucuacgacc cacucguauu cccuucagac gaauuugacg caucuauauc ccaaguuaac     1440

gaaaaaauca accaaucauu agccuuuaua agaaaauccg acgaauuauu acauaacguc     1500

aacgcuggaa aaucaacaac uaacauaaug auaaccacaa uaauaauagu caucauaguu     1560

auauuacuaa gucuaauagc cguaggccuc cuacuuuauu gcaaagcaag aucaacacca     1620

guaacauuau ccaaagacca acucagcggc auaaacaaua uagcuuuuuc aaacuaggga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6320
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6320
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcaa ucacaaccau acuaacugca      120

guuacuuucu gcuucgcauc cggccaaaac aucaccgaag aguucuacca aucaaccugc      180

uccgcagucu ccaaaggaua ccucggagcc cuucgcaccg gcugguacac cuccgucaua      240

accaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcacagacgc gaaagucaaa      300

cuuaucaaac aagaacucga caaauacaaa aacgccguca ccgaccugca gaugcucaug      360

ugcucaaccc ccgccacagg aagcggcucu gcuaucgcuu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaagucag cccuccucuc caccaacaaa      480

gccgucgucu cucucucaaa cggcguaucc guccucacau ucaaaguccu cgaccucaaa      540

aacuacaucg acaaacaacu ucuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

cccgaaacag ucauggaauu ucaacaaaag aacaaccgcc ucuuagaaau cacccgagaa      660

uuuuccguca acgcgggagu cacaaccccc guuucuacgu auaugcucac caacuccgaa      720

cuccuuuccc ucauaaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguccaaa ucguccgaca acaauccuac ucuauuaugu gcaucaucaa agaagaaguu      840

cucgccuacg ucguccaacu accccucuac ggcgugaucg acacccccug cuggaaacua      900

cacaccucac cccucugcac caccaacacc aaggaaggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcu ggcuccgucu cauucuuccc gcaagccgaa     1020

acuugcaaag uaugcuccaa cagaguauuc ugcgacacca ugaacucacu aacccucccu     1080

uccgaaguca accuuugcaa cguugacaua uucaacccaa aguacgauug caaaauuaug     1140

acauccaaaa cagaugucuc cuccuccguc aucacauccc ucggugccau uguaucaugc     1200

uacggaaaaa ccaaaugcac cgcauccaac aaaaacaaag gaaucaucaa aaccuucuca     1260

aacggcugcg auuacgucuc aaacaaagga gucgacacag ucuccgucgg aaacacccua     1320

uacuacguca acaaacaaga aggccaaucc cuguacguca aaggagaacc caucaucaac     1380

uucuacgacc cccucgucuu cccgagcgac gaguucgacg ccuccaucuc acaagucaau     1440

gaaaagauca accaaucccu ugccuucauc cggaaaucgg acgaacuccu acacaacgug     1500

aacgcuggaa aaucaaccac caacaucaug aucacaacca ucauuaucgu caucaucguc     1560

auacuccucu cccuaaucgc cgucggccuc cuccuguauu gcaaagcucg cuccaccccc     1620

gucacccugu ccaaagacca acucuccgga aucaacaaca ucgccuucuc aaacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  6321
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6321
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6322
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6322
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cuccaccccc     1620

gugacccuga gcaaggacca gcuguccggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6323
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6323
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6324
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6324
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gucaacaccu     1620

gugaccuuga guaaggauca gcugucuggg auuaacaaua ucgcuuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6325
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6325
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6326
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6326
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cagcacaccg     1620

gugacccugu cuaaggauca gcuuuccgga auuaacaaua ucgcguucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6327
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6327
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aaucuuaaaa gcaaaugcua uaaccacaau auuaacagca      120

guaacauucu guuuugccuc cggacaaaac auaacagaag aauuuuauca aucaacaugc      180

ucugcaguau ccaaagguua cuuaggcgca cuacgcacug gaugguauac aucaguaaua      240

acaauagaac uaucaaacau aaaagaaaau aaauguaacg guacugacgc aaaagugaaa      300

cuaauuaaac aagaacucga caaauacaaa aaugcuguaa cagaccuaca aaugcuaaug      360

ugcucaacac ccgcaaccgg aucaggauca gccauagccu ccggagucgc aguaugcaaa      420

guauuacauc uugaaggaga aguaaauaaa auaaaaucag cauuacuauc cacaaauaaa      480

gccguaguau cacuaucaaa cgguguaucc guccuuacau ucaaaguauu agaucuaaaa      540

aacuacauag auaaacaacu acuacccauc uuaaacaaac aaucaugcuc aauucccaac      600

ccagaaacag ucauggaauu ucaacaaaaa aacaacagac ucuuagaaau aacacgagaa      660

uuuucaguaa acgcaggagu aaccacacca guaaguacau acaugcucac caacucagaa      720

uuauuaucac uuauuaacga caugccaauu acaaacgacc aaaaaaaauu aaugucaaac      780

aauguccaaa uuguuagaca acaaucauac ucuauaaugu guauaauaaa agaagaagua      840

cuagcuuacg uaguucaauu accacuauau ggcguaauag auacaccuug cuggaaacua      900

cauacaucuc cauuauguac aacuaacaca aaagaaggau cuaacauaug ccuaacacgc      960

acagaucgag gaugguacug cgauaaugca gguuccguau cauucuuucc acaagcagaa     1020

acauguaaag uaugcucaaa cagaguauuc ugugacacua ugaacuccuu aacccuaccc     1080

ucagaaguca aucuaugcaa cguugacaua uuuaacccaa aauacgacug uaaaaucaug     1140

acaucuaaaa cagacguauc aucaucaguu auuacauccc uaggagcaau aguaucuugc     1200

uacggaaaaa caaaauguac agcauccaac aaaaacaaag gaauaaucaa aacauucuca     1260

aacggcugcg acuacguauc aaacaaaggu guagacacag uaucaguagg aaauacuuua     1320

uauuacguaa auaaacaaga aggacaaucu cuauacguua aaggcgaacc uauuauaaac     1380

uucuacgacc cacucguauu cccuucagac gaauuugacg caucuauauc ccaaguuaac     1440

gaaaaaauca accaaucauu agccuuuaua agaaaauccg acgaauuauu acauaacguc     1500

aacgcuggaa aaucaacaac uaacauaaug auaaccacaa uaauaauagu caucauaguu     1560

auauuacuaa gucuaauagc cguaggccuc cuacuuuauu gcaaagcaag aucaacacca     1620

guaacauuau ccaaagacca acucagcggc auaaacaaua uagcuuuuuc aaacuaggga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6328
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6328
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcaa ucacaaccau acuaacugca      120

guuacuuucu gcuucgcauc cggccaaaac aucaccgaag aguucuacca aucaaccugc      180

uccgcagucu ccaaaggaua ccucggagcc cuucgcaccg gcugguacac cuccgucaua      240

accaucgaac ucucaaacau aaaagaaaac aaaugcaacg gcacagacgc gaaagucaaa      300

cuuaucaaac aagaacucga caaauacaaa aacgccguca ccgaccugca gaugcucaug      360

ugcucaaccc ccgccacagg aagcggcucu gcuaucgcuu ccggcgucgc cgucugcaaa      420

guccuccacc ucgaaggcga aguaaacaaa aucaagucag cccuccucuc caccaacaaa      480

gccgucgucu cucucucaaa cggcguaucc guccucacau ucaaaguccu cgaccucaaa      540

aacuacaucg acaaacaacu ucuccccauc cuaaacaaac aaucaugcuc cauccccaac      600

cccgaaacag ucauggaauu ucaacaaaag aacaaccgcc ucuuagaaau cacccgagaa      660

uuuuccguca acgcgggagu cacaaccccc guuucuacgu auaugcucac caacuccgaa      720

cuccuuuccc ucauaaacga caugccaauc accaacgacc aaaagaaacu caugucaaac      780

aacguccaaa ucguccgaca acaauccuac ucuauuaugu gcaucaucaa agaagaaguu      840

cucgccuacg ucguccaacu accccucuac ggcgugaucg acacccccug cuggaaacua      900

cacaccucac cccucugcac caccaacacc aaggaaggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcu ggcuccgucu cauucuuccc gcaagccgaa     1020

acuugcaaag uaugcuccaa cagaguauuc ugcgacacca ugaacucacu aacccucccu     1080

uccgaaguca accuuugcaa cguugacaua uucaacccaa aguacgauug caaaauuaug     1140

acauccaaaa cagaugucuc cuccuccguc aucacauccc ucggugccau uguaucaugc     1200

uacggaaaaa ccaaaugcac cgcauccaac aaaaacaaag gaaucaucaa aaccuucuca     1260

aacggcugcg auuacgucuc aaacaaagga gucgacacag ucuccgucgg aaacacccua     1320

uacuacguca acaaacaaga aggccaaucc cuguacguca aaggagaacc caucaucaac     1380

uucuacgacc cccucgucuu cccgagcgac gaguucgacg ccuccaucuc acaagucaau     1440

gaaaagauca accaaucccu ugccuucauc cggaaaucgg acgaacuccu acacaacgug     1500

aacgcuggaa aaucaaccac caacaucaug aucacaacca ucauuaucgu caucaucguc     1560

auacuccucu cccuaaucgc cgucggccuc cuccuguauu gcaaagcucg cuccaccccc     1620

gucacccugu ccaaagacca acucuccgga aucaacaaca ucgccuucuc aaacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  6329
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6329
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6330
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6330
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcuc cacccccgug acccugagca aggaccagcu guccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6331
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6331
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6332
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6332
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacgguc aacaccugug accuugagua aggaucagcu gucugggauu     1680

aacaauaucg cuuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6333
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6333
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6334
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6334
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcag cacaccggug acccugucua aggaucagcu uuccggaauu     1680

aacaauaucg cguucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6335
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6335
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau cuuaaaagca      120

aaugcuauaa ccacaauauu aacagcagua acauucuguu uugccuccgg acaaaacaua      180

acagaagaau uuuaucaauc aacaugcucu gcaguaucca aagguuacuu aggcgcacua      240

cgcacuggau gguauacauc aguaauaaca auagaacuau caaacauaaa agaaaauaaa      300

uguaacggua cugacgcaaa agugaaacua auuaaacaag aacucgacaa auacaaaaau      360

gcuguaacag accuacaaau gcuaaugugc ucaacacccg caaccggauc aggaucagcc      420

auagccuccg gagucgcagu augcaaagua uuacaucuug aaggagaagu aaauaaaaua      480

aaaucagcau uacuauccac aaauaaagcc guaguaucac uaucaaacgg uguauccguc      540

cuuacauuca aaguauuaga ucuaaaaaac uacauagaua aacaacuacu acccaucuua      600

aacaaacaau caugcucaau ucccaaccca gaaacaguca uggaauuuca acaaaaaaac      660

aacagacucu uagaaauaac acgagaauuu ucaguaaacg caggaguaac cacaccagua      720

aguacauaca ugcucaccaa cucagaauua uuaucacuua uuaacgacau gccaauuaca      780

aacgaccaaa aaaaauuaau gucaaacaau guccaaauug uuagacaaca aucauacucu      840

auaaugugua uaauaaaaga agaaguacua gcuuacguag uucaauuacc acuauauggc      900

guaauagaua caccuugcug gaaacuacau acaucuccau uauguacaac uaacacaaaa      960

gaaggaucua acauaugccu aacacgcaca gaucgaggau gguacugcga uaaugcaggu     1020

uccguaucau ucuuuccaca agcagaaaca uguaaaguau gcucaaacag aguauucugu     1080

gacacuauga acuccuuaac ccuacccuca gaagucaauc uaugcaacgu ugacauauuu     1140

aacccaaaau acgacuguaa aaucaugaca ucuaaaacag acguaucauc aucaguuauu     1200

acaucccuag gagcaauagu aucuugcuac ggaaaaacaa aauguacagc auccaacaaa     1260

aacaaaggaa uaaucaaaac auucucaaac ggcugcgacu acguaucaaa caaaggugua     1320

gacacaguau caguaggaaa uacuuuauau uacguaaaua aacaagaagg acaaucucua     1380

uacguuaaag gcgaaccuau uauaaacuuc uacgacccac ucguauuccc uucagacgaa     1440

uuugacgcau cuauauccca aguuaacgaa aaaaucaacc aaucauuagc cuuuauaaga     1500

aaauccgacg aauuauuaca uaacgucaac gcuggaaaau caacaacuaa cauaaugaua     1560

accacaauaa uaauagucau cauaguuaua uuacuaaguc uaauagccgu aggccuccua     1620

cuuuauugca aagcaagauc aacaccagua acauuaucca aagaccaacu cagcggcaua     1680

aacaauauag cuuuuucaaa cuagggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6336
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6336
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgcaauca caaccauacu aacugcaguu acuuucugcu ucgcauccgg ccaaaacauc      180

accgaagagu ucuaccaauc aaccugcucc gcagucucca aaggauaccu cggagcccuu      240

cgcaccggcu gguacaccuc cgucauaacc aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca cagacgcgaa agucaaacuu aucaaacaag aacucgacaa auacaaaaac      360

gccgucaccg accugcagau gcucaugugc ucaacccccg ccacaggaag cggcucugcu      420

aucgcuuccg gcgucgccgu cugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aagucagccc uccucuccac caacaaagcc gucgucucuc ucucaaacgg cguauccguc      540

cucacauuca aaguccucga ccucaaaaac uacaucgaca aacaacuucu ccccauccua      600

aacaaacaau caugcuccau ccccaacccc gaaacaguca uggaauuuca acaaaagaac      660

aaccgccucu uagaaaucac ccgagaauuu uccgucaacg cgggagucac aacccccguu      720

ucuacguaua ugcucaccaa cuccgaacuc cuuucccuca uaaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guccaaaucg uccgacaaca auccuacucu      840

auuaugugca ucaucaaaga agaaguucuc gccuacgucg uccaacuacc ccucuacggc      900

gugaucgaca cccccugcug gaaacuacac accucacccc ucugcaccac caacaccaag      960

gaaggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgcuggc     1020

uccgucucau ucuucccgca agccgaaacu ugcaaaguau gcuccaacag aguauucugc     1080

gacaccauga acucacuaac ccucccuucc gaagucaacc uuugcaacgu ugacauauuc     1140

aacccaaagu acgauugcaa aauuaugaca uccaaaacag augucuccuc cuccgucauc     1200

acaucccucg gugccauugu aucaugcuac ggaaaaacca aaugcaccgc auccaacaaa     1260

aacaaaggaa ucaucaaaac cuucucaaac ggcugcgauu acgucucaaa caaaggaguc     1320

gacacagucu ccgucggaaa cacccuauac uacgucaaca aacaagaagg ccaaucccug     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc ucgucuuccc gagcgacgag     1440

uucgacgccu ccaucucaca agucaaugaa aagaucaacc aaucccuugc cuucauccgg     1500

aaaucggacg aacuccuaca caacgugaac gcuggaaaau caaccaccaa caucaugauc     1560

acaaccauca uuaucgucau caucgucaua cuccucuccc uaaucgccgu cggccuccuc     1620

cuguauugca aagcucgcuc cacccccguc acccugucca aagaccaacu cuccggaauc     1680

aacaacaucg ccuucucaaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  6337
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6337
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6338
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6338
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcuc cacccccgug acccugagca aggaccagcu guccggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6339
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6339
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6340
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6340
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacgguc aacaccugug accuugagua aggaucagcu gucugggauu     1680

aacaauaucg cuuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6341
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6341
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6342
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6342
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcag cacaccggug acccugucua aggaucagcu uuccggaauu     1680

aacaauaucg cguucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6343
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6343
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau cuuaaaagca      120

aaugcuauaa ccacaauauu aacagcagua acauucuguu uugccuccgg acaaaacaua      180

acagaagaau uuuaucaauc aacaugcucu gcaguaucca aagguuacuu aggcgcacua      240

cgcacuggau gguauacauc aguaauaaca auagaacuau caaacauaaa agaaaauaaa      300

uguaacggua cugacgcaaa agugaaacua auuaaacaag aacucgacaa auacaaaaau      360

gcuguaacag accuacaaau gcuaaugugc ucaacacccg caaccggauc aggaucagcc      420

auagccuccg gagucgcagu augcaaagua uuacaucuug aaggagaagu aaauaaaaua      480

aaaucagcau uacuauccac aaauaaagcc guaguaucac uaucaaacgg uguauccguc      540

cuuacauuca aaguauuaga ucuaaaaaac uacauagaua aacaacuacu acccaucuua      600

aacaaacaau caugcucaau ucccaaccca gaaacaguca uggaauuuca acaaaaaaac      660

aacagacucu uagaaauaac acgagaauuu ucaguaaacg caggaguaac cacaccagua      720

aguacauaca ugcucaccaa cucagaauua uuaucacuua uuaacgacau gccaauuaca      780

aacgaccaaa aaaaauuaau gucaaacaau guccaaauug uuagacaaca aucauacucu      840

auaaugugua uaauaaaaga agaaguacua gcuuacguag uucaauuacc acuauauggc      900

guaauagaua caccuugcug gaaacuacau acaucuccau uauguacaac uaacacaaaa      960

gaaggaucua acauaugccu aacacgcaca gaucgaggau gguacugcga uaaugcaggu     1020

uccguaucau ucuuuccaca agcagaaaca uguaaaguau gcucaaacag aguauucugu     1080

gacacuauga acuccuuaac ccuacccuca gaagucaauc uaugcaacgu ugacauauuu     1140

aacccaaaau acgacuguaa aaucaugaca ucuaaaacag acguaucauc aucaguuauu     1200

acaucccuag gagcaauagu aucuugcuac ggaaaaacaa aauguacagc auccaacaaa     1260

aacaaaggaa uaaucaaaac auucucaaac ggcugcgacu acguaucaaa caaaggugua     1320

gacacaguau caguaggaaa uacuuuauau uacguaaaua aacaagaagg acaaucucua     1380

uacguuaaag gcgaaccuau uauaaacuuc uacgacccac ucguauuccc uucagacgaa     1440

uuugacgcau cuauauccca aguuaacgaa aaaaucaacc aaucauuagc cuuuauaaga     1500

aaauccgacg aauuauuaca uaacgucaac gcuggaaaau caacaacuaa cauaaugaua     1560

accacaauaa uaauagucau cauaguuaua uuacuaaguc uaauagccgu aggccuccua     1620

cuuuauugca aagcaagauc aacaccagua acauuaucca aagaccaacu cagcggcaua     1680

aacaauauag cuuuuucaaa cuagggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6344
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6344
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgcaauca caaccauacu aacugcaguu acuuucugcu ucgcauccgg ccaaaacauc      180

accgaagagu ucuaccaauc aaccugcucc gcagucucca aaggauaccu cggagcccuu      240

cgcaccggcu gguacaccuc cgucauaacc aucgaacucu caaacauaaa agaaaacaaa      300

ugcaacggca cagacgcgaa agucaaacuu aucaaacaag aacucgacaa auacaaaaac      360

gccgucaccg accugcagau gcucaugugc ucaacccccg ccacaggaag cggcucugcu      420

aucgcuuccg gcgucgccgu cugcaaaguc cuccaccucg aaggcgaagu aaacaaaauc      480

aagucagccc uccucuccac caacaaagcc gucgucucuc ucucaaacgg cguauccguc      540

cucacauuca aaguccucga ccucaaaaac uacaucgaca aacaacuucu ccccauccua      600

aacaaacaau caugcuccau ccccaacccc gaaacaguca uggaauuuca acaaaagaac      660

aaccgccucu uagaaaucac ccgagaauuu uccgucaacg cgggagucac aacccccguu      720

ucuacguaua ugcucaccaa cuccgaacuc cuuucccuca uaaacgacau gccaaucacc      780

aacgaccaaa agaaacucau gucaaacaac guccaaaucg uccgacaaca auccuacucu      840

auuaugugca ucaucaaaga agaaguucuc gccuacgucg uccaacuacc ccucuacggc      900

gugaucgaca cccccugcug gaaacuacac accucacccc ucugcaccac caacaccaag      960

gaaggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgcuggc     1020

uccgucucau ucuucccgca agccgaaacu ugcaaaguau gcuccaacag aguauucugc     1080

gacaccauga acucacuaac ccucccuucc gaagucaacc uuugcaacgu ugacauauuc     1140

aacccaaagu acgauugcaa aauuaugaca uccaaaacag augucuccuc cuccgucauc     1200

acaucccucg gugccauugu aucaugcuac ggaaaaacca aaugcaccgc auccaacaaa     1260

aacaaaggaa ucaucaaaac cuucucaaac ggcugcgauu acgucucaaa caaaggaguc     1320

gacacagucu ccgucggaaa cacccuauac uacgucaaca aacaagaagg ccaaucccug     1380

uacgucaaag gagaacccau caucaacuuc uacgaccccc ucgucuuccc gagcgacgag     1440

uucgacgccu ccaucucaca agucaaugaa aagaucaacc aaucccuugc cuucauccgg     1500

aaaucggacg aacuccuaca caacgugaac gcuggaaaau caaccaccaa caucaugauc     1560

acaaccauca uuaucgucau caucgucaua cuccucuccc uaaucgccgu cggccuccuc     1620

cuguauugca aagcucgcuc cacccccguc acccugucca aagaccaacu cuccggaauc     1680

aacaacaucg ccuucucaaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  6345
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6345
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6346
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6346
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcuccac ccccgugacc     1680

cugagcaagg accagcuguc cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6347
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6347
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6348
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6348
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggucaac accugugacc     1680

uugaguaagg aucagcuguc ugggauuaac aauaucgcuu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6349
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6349
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6350
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6350
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcagcac accggugacc     1680

cugucuaagg aucagcuuuc cggaauuaac aauaucgcgu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6351
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6351
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaaucuu aaaagcaaau gcuauaacca caauauuaac agcaguaaca      180

uucuguuuug ccuccggaca aaacauaaca gaagaauuuu aucaaucaac augcucugca      240

guauccaaag guuacuuagg cgcacuacgc acuggauggu auacaucagu aauaacaaua      300

gaacuaucaa acauaaaaga aaauaaaugu aacgguacug acgcaaaagu gaaacuaauu      360

aaacaagaac ucgacaaaua caaaaaugcu guaacagacc uacaaaugcu aaugugcuca      420

acacccgcaa ccggaucagg aucagccaua gccuccggag ucgcaguaug caaaguauua      480

caucuugaag gagaaguaaa uaaaauaaaa ucagcauuac uauccacaaa uaaagccgua      540

guaucacuau caaacggugu auccguccuu acauucaaag uauuagaucu aaaaaacuac      600

auagauaaac aacuacuacc caucuuaaac aaacaaucau gcucaauucc caacccagaa      660

acagucaugg aauuucaaca aaaaaacaac agacucuuag aaauaacacg agaauuuuca      720

guaaacgcag gaguaaccac accaguaagu acauacaugc ucaccaacuc agaauuauua      780

ucacuuauua acgacaugcc aauuacaaac gaccaaaaaa aauuaauguc aaacaauguc      840

caaauuguua gacaacaauc auacucuaua auguguauaa uaaaagaaga aguacuagcu      900

uacguaguuc aauuaccacu auauggcgua auagauacac cuugcuggaa acuacauaca      960

ucuccauuau guacaacuaa cacaaaagaa ggaucuaaca uaugccuaac acgcacagau     1020

cgaggauggu acugcgauaa ugcagguucc guaucauucu uuccacaagc agaaacaugu     1080

aaaguaugcu caaacagagu auucugugac acuaugaacu ccuuaacccu acccucagaa     1140

gucaaucuau gcaacguuga cauauuuaac ccaaaauacg acuguaaaau caugacaucu     1200

aaaacagacg uaucaucauc aguuauuaca ucccuaggag caauaguauc uugcuacgga     1260

aaaacaaaau guacagcauc caacaaaaac aaaggaauaa ucaaaacauu cucaaacggc     1320

ugcgacuacg uaucaaacaa agguguagac acaguaucag uaggaaauac uuuauauuac     1380

guaaauaaac aagaaggaca aucucuauac guuaaaggcg aaccuauuau aaacuucuac     1440

gacccacucg uauucccuuc agacgaauuu gacgcaucua uaucccaagu uaacgaaaaa     1500

aucaaccaau cauuagccuu uauaagaaaa uccgacgaau uauuacauaa cgucaacgcu     1560

ggaaaaucaa caacuaacau aaugauaacc acaauaauaa uagucaucau aguuauauua     1620

cuaagucuaa uagccguagg ccuccuacuu uauugcaaag caagaucaac accaguaaca     1680

uuauccaaag accaacucag cggcauaaac aauauagcuu uuucaaacua gggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6352
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6352
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gcaaucacaa ccauacuaac ugcaguuacu      180

uucugcuucg cauccggcca aaacaucacc gaagaguucu accaaucaac cugcuccgca      240

gucuccaaag gauaccucgg agcccuucgc accggcuggu acaccuccgu cauaaccauc      300

gaacucucaa acauaaaaga aaacaaaugc aacggcacag acgcgaaagu caaacuuauc      360

aaacaagaac ucgacaaaua caaaaacgcc gucaccgacc ugcagaugcu caugugcuca      420

acccccgcca caggaagcgg cucugcuauc gcuuccggcg ucgccgucug caaaguccuc      480

caccucgaag gcgaaguaaa caaaaucaag ucagcccucc ucuccaccaa caaagccguc      540

gucucucucu caaacggcgu auccguccuc acauucaaag uccucgaccu caaaaacuac      600

aucgacaaac aacuucuccc cauccuaaac aaacaaucau gcuccauccc caaccccgaa      660

acagucaugg aauuucaaca aaagaacaac cgccucuuag aaaucacccg agaauuuucc      720

gucaacgcgg gagucacaac ccccguuucu acguauaugc ucaccaacuc cgaacuccuu      780

ucccucauaa acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacguc      840

caaaucgucc gacaacaauc cuacucuauu augugcauca ucaaagaaga aguucucgcc      900

uacgucgucc aacuaccccu cuacggcgug aucgacaccc ccugcuggaa acuacacacc      960

ucaccccucu gcaccaccaa caccaaggaa ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgcuggcucc gucucauucu ucccgcaagc cgaaacuugc     1080

aaaguaugcu ccaacagagu auucugcgac accaugaacu cacuaacccu cccuuccgaa     1140

gucaaccuuu gcaacguuga cauauucaac ccaaaguacg auugcaaaau uaugacaucc     1200

aaaacagaug ucuccuccuc cgucaucaca ucccucggug ccauuguauc augcuacgga     1260

aaaaccaaau gcaccgcauc caacaaaaac aaaggaauca ucaaaaccuu cucaaacggc     1320

ugcgauuacg ucucaaacaa aggagucgac acagucuccg ucggaaacac ccuauacuac     1380

gucaacaaac aagaaggcca aucccuguac gucaaaggag aacccaucau caacuucuac     1440

gacccccucg ucuucccgag cgacgaguuc gacgccucca ucucacaagu caaugaaaag     1500

aucaaccaau cccuugccuu cauccggaaa ucggacgaac uccuacacaa cgugaacgcu     1560

ggaaaaucaa ccaccaacau caugaucaca accaucauua ucgucaucau cgucauacuc     1620

cucucccuaa ucgccgucgg ccuccuccug uauugcaaag cucgcuccac ccccgucacc     1680

cuguccaaag accaacucuc cggaaucaac aacaucgccu ucucaaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6353
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6353
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6354
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6354
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cuccaccccc gugacccuga gcaaggacca gcuguccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6355
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6355
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6356
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6356
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gucaacaccu gugaccuuga guaaggauca gcugucuggg     1680

auuaacaaua ucgcuuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6357
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6357
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6358
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6358
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cagcacaccg gugacccugu cuaaggauca gcuuuccgga     1680

auuaacaaua ucgcguucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6359
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6359
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aaucuuaaaa      120

gcaaaugcua uaaccacaau auuaacagca guaacauucu guuuugccuc cggacaaaac      180

auaacagaag aauuuuauca aucaacaugc ucugcaguau ccaaagguua cuuaggcgca      240

cuacgcacug gaugguauac aucaguaaua acaauagaac uaucaaacau aaaagaaaau      300

aaauguaacg guacugacgc aaaagugaaa cuaauuaaac aagaacucga caaauacaaa      360

aaugcuguaa cagaccuaca aaugcuaaug ugcucaacac ccgcaaccgg aucaggauca      420

gccauagccu ccggagucgc aguaugcaaa guauuacauc uugaaggaga aguaaauaaa      480

auaaaaucag cauuacuauc cacaaauaaa gccguaguau cacuaucaaa cgguguaucc      540

guccuuacau ucaaaguauu agaucuaaaa aacuacauag auaaacaacu acuacccauc      600

uuaaacaaac aaucaugcuc aauucccaac ccagaaacag ucauggaauu ucaacaaaaa      660

aacaacagac ucuuagaaau aacacgagaa uuuucaguaa acgcaggagu aaccacacca      720

guaaguacau acaugcucac caacucagaa uuauuaucac uuauuaacga caugccaauu      780

acaaacgacc aaaaaaaauu aaugucaaac aauguccaaa uuguuagaca acaaucauac      840

ucuauaaugu guauaauaaa agaagaagua cuagcuuacg uaguucaauu accacuauau      900

ggcguaauag auacaccuug cuggaaacua cauacaucuc cauuauguac aacuaacaca      960

aaagaaggau cuaacauaug ccuaacacgc acagaucgag gaugguacug cgauaaugca     1020

gguuccguau cauucuuucc acaagcagaa acauguaaag uaugcucaaa cagaguauuc     1080

ugugacacua ugaacuccuu aacccuaccc ucagaaguca aucuaugcaa cguugacaua     1140

uuuaacccaa aauacgacug uaaaaucaug acaucuaaaa cagacguauc aucaucaguu     1200

auuacauccc uaggagcaau aguaucuugc uacggaaaaa caaaauguac agcauccaac     1260

aaaaacaaag gaauaaucaa aacauucuca aacggcugcg acuacguauc aaacaaaggu     1320

guagacacag uaucaguagg aaauacuuua uauuacguaa auaaacaaga aggacaaucu     1380

cuauacguua aaggcgaacc uauuauaaac uucuacgacc cacucguauu cccuucagac     1440

gaauuugacg caucuauauc ccaaguuaac gaaaaaauca accaaucauu agccuuuaua     1500

agaaaauccg acgaauuauu acauaacguc aacgcuggaa aaucaacaac uaacauaaug     1560

auaaccacaa uaauaauagu caucauaguu auauuacuaa gucuaauagc cguaggccuc     1620

cuacuuuauu gcaaagcaag aucaacacca guaacauuau ccaaagacca acucagcggc     1680

auaaacaaua uagcuuuuuc aaacuaggga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6360
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6360
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcaa ucacaaccau acuaacugca guuacuuucu gcuucgcauc cggccaaaac      180

aucaccgaag aguucuacca aucaaccugc uccgcagucu ccaaaggaua ccucggagcc      240

cuucgcaccg gcugguacac cuccgucaua accaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcacagacgc gaaagucaaa cuuaucaaac aagaacucga caaauacaaa      360

aacgccguca ccgaccugca gaugcucaug ugcucaaccc ccgccacagg aagcggcucu      420

gcuaucgcuu ccggcgucgc cgucugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaagucag cccuccucuc caccaacaaa gccgucgucu cucucucaaa cggcguaucc      540

guccucacau ucaaaguccu cgaccucaaa aacuacaucg acaaacaacu ucuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac cccgaaacag ucauggaauu ucaacaaaag      660

aacaaccgcc ucuuagaaau cacccgagaa uuuuccguca acgcgggagu cacaaccccc      720

guuucuacgu auaugcucac caacuccgaa cuccuuuccc ucauaaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgaca acaauccuac      840

ucuauuaugu gcaucaucaa agaagaaguu cucgccuacg ucguccaacu accccucuac      900

ggcgugaucg acacccccug cuggaaacua cacaccucac cccucugcac caccaacacc      960

aaggaaggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcu     1020

ggcuccgucu cauucuuccc gcaagccgaa acuugcaaag uaugcuccaa cagaguauuc     1080

ugcgacacca ugaacucacu aacccucccu uccgaaguca accuuugcaa cguugacaua     1140

uucaacccaa aguacgauug caaaauuaug acauccaaaa cagaugucuc cuccuccguc     1200

aucacauccc ucggugccau uguaucaugc uacggaaaaa ccaaaugcac cgcauccaac     1260

aaaaacaaag gaaucaucaa aaccuucuca aacggcugcg auuacgucuc aaacaaagga     1320

gucgacacag ucuccgucgg aaacacccua uacuacguca acaaacaaga aggccaaucc     1380

cuguacguca aaggagaacc caucaucaac uucuacgacc cccucgucuu cccgagcgac     1440

gaguucgacg ccuccaucuc acaagucaau gaaaagauca accaaucccu ugccuucauc     1500

cggaaaucgg acgaacuccu acacaacgug aacgcuggaa aaucaaccac caacaucaug     1560

aucacaacca ucauuaucgu caucaucguc auacuccucu cccuaaucgc cgucggccuc     1620

cuccuguauu gcaaagcucg cuccaccccc gucacccugu ccaaagacca acucuccgga     1680

aucaacaaca ucgccuucuc aaacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  6361
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6361
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6362
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6362
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cuccaccccc gugacccuga gcaaggacca gcuguccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6363
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6363
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6364
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6364
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gucaacaccu gugaccuuga guaaggauca gcugucuggg     1680

auuaacaaua ucgcuuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6365
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6365
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6366
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6366
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cagcacaccg gugacccugu cuaaggauca gcuuuccgga     1680

auuaacaaua ucgcguucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6367
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6367
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aaucuuaaaa      120

gcaaaugcua uaaccacaau auuaacagca guaacauucu guuuugccuc cggacaaaac      180

auaacagaag aauuuuauca aucaacaugc ucugcaguau ccaaagguua cuuaggcgca      240

cuacgcacug gaugguauac aucaguaaua acaauagaac uaucaaacau aaaagaaaau      300

aaauguaacg guacugacgc aaaagugaaa cuaauuaaac aagaacucga caaauacaaa      360

aaugcuguaa cagaccuaca aaugcuaaug ugcucaacac ccgcaaccgg aucaggauca      420

gccauagccu ccggagucgc aguaugcaaa guauuacauc uugaaggaga aguaaauaaa      480

auaaaaucag cauuacuauc cacaaauaaa gccguaguau cacuaucaaa cgguguaucc      540

guccuuacau ucaaaguauu agaucuaaaa aacuacauag auaaacaacu acuacccauc      600

uuaaacaaac aaucaugcuc aauucccaac ccagaaacag ucauggaauu ucaacaaaaa      660

aacaacagac ucuuagaaau aacacgagaa uuuucaguaa acgcaggagu aaccacacca      720

guaaguacau acaugcucac caacucagaa uuauuaucac uuauuaacga caugccaauu      780

acaaacgacc aaaaaaaauu aaugucaaac aauguccaaa uuguuagaca acaaucauac      840

ucuauaaugu guauaauaaa agaagaagua cuagcuuacg uaguucaauu accacuauau      900

ggcguaauag auacaccuug cuggaaacua cauacaucuc cauuauguac aacuaacaca      960

aaagaaggau cuaacauaug ccuaacacgc acagaucgag gaugguacug cgauaaugca     1020

gguuccguau cauucuuucc acaagcagaa acauguaaag uaugcucaaa cagaguauuc     1080

ugugacacua ugaacuccuu aacccuaccc ucagaaguca aucuaugcaa cguugacaua     1140

uuuaacccaa aauacgacug uaaaaucaug acaucuaaaa cagacguauc aucaucaguu     1200

auuacauccc uaggagcaau aguaucuugc uacggaaaaa caaaauguac agcauccaac     1260

aaaaacaaag gaauaaucaa aacauucuca aacggcugcg acuacguauc aaacaaaggu     1320

guagacacag uaucaguagg aaauacuuua uauuacguaa auaaacaaga aggacaaucu     1380

cuauacguua aaggcgaacc uauuauaaac uucuacgacc cacucguauu cccuucagac     1440

gaauuugacg caucuauauc ccaaguuaac gaaaaaauca accaaucauu agccuuuaua     1500

agaaaauccg acgaauuauu acauaacguc aacgcuggaa aaucaacaac uaacauaaug     1560

auaaccacaa uaauaauagu caucauaguu auauuacuaa gucuaauagc cguaggccuc     1620

cuacuuuauu gcaaagcaag aucaacacca guaacauuau ccaaagacca acucagcggc     1680

auaaacaaua uagcuuuuuc aaacuaggga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6368
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6368
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcaa ucacaaccau acuaacugca guuacuuucu gcuucgcauc cggccaaaac      180

aucaccgaag aguucuacca aucaaccugc uccgcagucu ccaaaggaua ccucggagcc      240

cuucgcaccg gcugguacac cuccgucaua accaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcacagacgc gaaagucaaa cuuaucaaac aagaacucga caaauacaaa      360

aacgccguca ccgaccugca gaugcucaug ugcucaaccc ccgccacagg aagcggcucu      420

gcuaucgcuu ccggcgucgc cgucugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaagucag cccuccucuc caccaacaaa gccgucgucu cucucucaaa cggcguaucc      540

guccucacau ucaaaguccu cgaccucaaa aacuacaucg acaaacaacu ucuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac cccgaaacag ucauggaauu ucaacaaaag      660

aacaaccgcc ucuuagaaau cacccgagaa uuuuccguca acgcgggagu cacaaccccc      720

guuucuacgu auaugcucac caacuccgaa cuccuuuccc ucauaaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgaca acaauccuac      840

ucuauuaugu gcaucaucaa agaagaaguu cucgccuacg ucguccaacu accccucuac      900

ggcgugaucg acacccccug cuggaaacua cacaccucac cccucugcac caccaacacc      960

aaggaaggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcu     1020

ggcuccgucu cauucuuccc gcaagccgaa acuugcaaag uaugcuccaa cagaguauuc     1080

ugcgacacca ugaacucacu aacccucccu uccgaaguca accuuugcaa cguugacaua     1140

uucaacccaa aguacgauug caaaauuaug acauccaaaa cagaugucuc cuccuccguc     1200

aucacauccc ucggugccau uguaucaugc uacggaaaaa ccaaaugcac cgcauccaac     1260

aaaaacaaag gaaucaucaa aaccuucuca aacggcugcg auuacgucuc aaacaaagga     1320

gucgacacag ucuccgucgg aaacacccua uacuacguca acaaacaaga aggccaaucc     1380

cuguacguca aaggagaacc caucaucaac uucuacgacc cccucgucuu cccgagcgac     1440

gaguucgacg ccuccaucuc acaagucaau gaaaagauca accaaucccu ugccuucauc     1500

cggaaaucgg acgaacuccu acacaacgug aacgcuggaa aaucaaccac caacaucaug     1560

aucacaacca ucauuaucgu caucaucguc auacuccucu cccuaaucgc cgucggccuc     1620

cuccuguauu gcaaagcucg cuccaccccc gucacccugu ccaaagacca acucuccgga     1680

aucaacaaca ucgccuucuc aaacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  6369
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6369
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6370
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6370
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cuccaccccc gugacccuga gcaaggacca gcuguccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6371
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6371
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6372
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6372
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gucaacaccu gugaccuuga guaaggauca gcugucuggg     1680

auuaacaaua ucgcuuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6373
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6373
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6374
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6374
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cagcacaccg gugacccugu cuaaggauca gcuuuccgga     1680

auuaacaaua ucgcguucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6375
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6375
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aaucuuaaaa      120

gcaaaugcua uaaccacaau auuaacagca guaacauucu guuuugccuc cggacaaaac      180

auaacagaag aauuuuauca aucaacaugc ucugcaguau ccaaagguua cuuaggcgca      240

cuacgcacug gaugguauac aucaguaaua acaauagaac uaucaaacau aaaagaaaau      300

aaauguaacg guacugacgc aaaagugaaa cuaauuaaac aagaacucga caaauacaaa      360

aaugcuguaa cagaccuaca aaugcuaaug ugcucaacac ccgcaaccgg aucaggauca      420

gccauagccu ccggagucgc aguaugcaaa guauuacauc uugaaggaga aguaaauaaa      480

auaaaaucag cauuacuauc cacaaauaaa gccguaguau cacuaucaaa cgguguaucc      540

guccuuacau ucaaaguauu agaucuaaaa aacuacauag auaaacaacu acuacccauc      600

uuaaacaaac aaucaugcuc aauucccaac ccagaaacag ucauggaauu ucaacaaaaa      660

aacaacagac ucuuagaaau aacacgagaa uuuucaguaa acgcaggagu aaccacacca      720

guaaguacau acaugcucac caacucagaa uuauuaucac uuauuaacga caugccaauu      780

acaaacgacc aaaaaaaauu aaugucaaac aauguccaaa uuguuagaca acaaucauac      840

ucuauaaugu guauaauaaa agaagaagua cuagcuuacg uaguucaauu accacuauau      900

ggcguaauag auacaccuug cuggaaacua cauacaucuc cauuauguac aacuaacaca      960

aaagaaggau cuaacauaug ccuaacacgc acagaucgag gaugguacug cgauaaugca     1020

gguuccguau cauucuuucc acaagcagaa acauguaaag uaugcucaaa cagaguauuc     1080

ugugacacua ugaacuccuu aacccuaccc ucagaaguca aucuaugcaa cguugacaua     1140

uuuaacccaa aauacgacug uaaaaucaug acaucuaaaa cagacguauc aucaucaguu     1200

auuacauccc uaggagcaau aguaucuugc uacggaaaaa caaaauguac agcauccaac     1260

aaaaacaaag gaauaaucaa aacauucuca aacggcugcg acuacguauc aaacaaaggu     1320

guagacacag uaucaguagg aaauacuuua uauuacguaa auaaacaaga aggacaaucu     1380

cuauacguua aaggcgaacc uauuauaaac uucuacgacc cacucguauu cccuucagac     1440

gaauuugacg caucuauauc ccaaguuaac gaaaaaauca accaaucauu agccuuuaua     1500

agaaaauccg acgaauuauu acauaacguc aacgcuggaa aaucaacaac uaacauaaug     1560

auaaccacaa uaauaauagu caucauaguu auauuacuaa gucuaauagc cguaggccuc     1620

cuacuuuauu gcaaagcaag aucaacacca guaacauuau ccaaagacca acucagcggc     1680

auaaacaaua uagcuuuuuc aaacuaggga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6376
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6376
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcaa ucacaaccau acuaacugca guuacuuucu gcuucgcauc cggccaaaac      180

aucaccgaag aguucuacca aucaaccugc uccgcagucu ccaaaggaua ccucggagcc      240

cuucgcaccg gcugguacac cuccgucaua accaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcacagacgc gaaagucaaa cuuaucaaac aagaacucga caaauacaaa      360

aacgccguca ccgaccugca gaugcucaug ugcucaaccc ccgccacagg aagcggcucu      420

gcuaucgcuu ccggcgucgc cgucugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaagucag cccuccucuc caccaacaaa gccgucgucu cucucucaaa cggcguaucc      540

guccucacau ucaaaguccu cgaccucaaa aacuacaucg acaaacaacu ucuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac cccgaaacag ucauggaauu ucaacaaaag      660

aacaaccgcc ucuuagaaau cacccgagaa uuuuccguca acgcgggagu cacaaccccc      720

guuucuacgu auaugcucac caacuccgaa cuccuuuccc ucauaaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgaca acaauccuac      840

ucuauuaugu gcaucaucaa agaagaaguu cucgccuacg ucguccaacu accccucuac      900

ggcgugaucg acacccccug cuggaaacua cacaccucac cccucugcac caccaacacc      960

aaggaaggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcu     1020

ggcuccgucu cauucuuccc gcaagccgaa acuugcaaag uaugcuccaa cagaguauuc     1080

ugcgacacca ugaacucacu aacccucccu uccgaaguca accuuugcaa cguugacaua     1140

uucaacccaa aguacgauug caaaauuaug acauccaaaa cagaugucuc cuccuccguc     1200

aucacauccc ucggugccau uguaucaugc uacggaaaaa ccaaaugcac cgcauccaac     1260

aaaaacaaag gaaucaucaa aaccuucuca aacggcugcg auuacgucuc aaacaaagga     1320

gucgacacag ucuccgucgg aaacacccua uacuacguca acaaacaaga aggccaaucc     1380

cuguacguca aaggagaacc caucaucaac uucuacgacc cccucgucuu cccgagcgac     1440

gaguucgacg ccuccaucuc acaagucaau gaaaagauca accaaucccu ugccuucauc     1500

cggaaaucgg acgaacuccu acacaacgug aacgcuggaa aaucaaccac caacaucaug     1560

aucacaacca ucauuaucgu caucaucguc auacuccucu cccuaaucgc cgucggccuc     1620

cuccuguauu gcaaagcucg cuccaccccc gucacccugu ccaaagacca acucuccgga     1680

aucaacaaca ucgccuucuc aaacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6377
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6377
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6378
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6378
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cuccaccccc gugacccuga gcaaggacca gcuguccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6379
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6379
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6380
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6380
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gucaacaccu gugaccuuga guaaggauca gcugucuggg     1680

auuaacaaua ucgcuuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6381
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6381
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6382
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6382
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cagcacaccg gugacccugu cuaaggauca gcuuuccgga     1680

auuaacaaua ucgcguucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6383
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6383
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aaucuuaaaa      120

gcaaaugcua uaaccacaau auuaacagca guaacauucu guuuugccuc cggacaaaac      180

auaacagaag aauuuuauca aucaacaugc ucugcaguau ccaaagguua cuuaggcgca      240

cuacgcacug gaugguauac aucaguaaua acaauagaac uaucaaacau aaaagaaaau      300

aaauguaacg guacugacgc aaaagugaaa cuaauuaaac aagaacucga caaauacaaa      360

aaugcuguaa cagaccuaca aaugcuaaug ugcucaacac ccgcaaccgg aucaggauca      420

gccauagccu ccggagucgc aguaugcaaa guauuacauc uugaaggaga aguaaauaaa      480

auaaaaucag cauuacuauc cacaaauaaa gccguaguau cacuaucaaa cgguguaucc      540

guccuuacau ucaaaguauu agaucuaaaa aacuacauag auaaacaacu acuacccauc      600

uuaaacaaac aaucaugcuc aauucccaac ccagaaacag ucauggaauu ucaacaaaaa      660

aacaacagac ucuuagaaau aacacgagaa uuuucaguaa acgcaggagu aaccacacca      720

guaaguacau acaugcucac caacucagaa uuauuaucac uuauuaacga caugccaauu      780

acaaacgacc aaaaaaaauu aaugucaaac aauguccaaa uuguuagaca acaaucauac      840

ucuauaaugu guauaauaaa agaagaagua cuagcuuacg uaguucaauu accacuauau      900

ggcguaauag auacaccuug cuggaaacua cauacaucuc cauuauguac aacuaacaca      960

aaagaaggau cuaacauaug ccuaacacgc acagaucgag gaugguacug cgauaaugca     1020

gguuccguau cauucuuucc acaagcagaa acauguaaag uaugcucaaa cagaguauuc     1080

ugugacacua ugaacuccuu aacccuaccc ucagaaguca aucuaugcaa cguugacaua     1140

uuuaacccaa aauacgacug uaaaaucaug acaucuaaaa cagacguauc aucaucaguu     1200

auuacauccc uaggagcaau aguaucuugc uacggaaaaa caaaauguac agcauccaac     1260

aaaaacaaag gaauaaucaa aacauucuca aacggcugcg acuacguauc aaacaaaggu     1320

guagacacag uaucaguagg aaauacuuua uauuacguaa auaaacaaga aggacaaucu     1380

cuauacguua aaggcgaacc uauuauaaac uucuacgacc cacucguauu cccuucagac     1440

gaauuugacg caucuauauc ccaaguuaac gaaaaaauca accaaucauu agccuuuaua     1500

agaaaauccg acgaauuauu acauaacguc aacgcuggaa aaucaacaac uaacauaaug     1560

auaaccacaa uaauaauagu caucauaguu auauuacuaa gucuaauagc cguaggccuc     1620

cuacuuuauu gcaaagcaag aucaacacca guaacauuau ccaaagacca acucagcggc     1680

auaaacaaua uagcuuuuuc aaacuaggga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6384
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6384
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcaa ucacaaccau acuaacugca guuacuuucu gcuucgcauc cggccaaaac      180

aucaccgaag aguucuacca aucaaccugc uccgcagucu ccaaaggaua ccucggagcc      240

cuucgcaccg gcugguacac cuccgucaua accaucgaac ucucaaacau aaaagaaaac      300

aaaugcaacg gcacagacgc gaaagucaaa cuuaucaaac aagaacucga caaauacaaa      360

aacgccguca ccgaccugca gaugcucaug ugcucaaccc ccgccacagg aagcggcucu      420

gcuaucgcuu ccggcgucgc cgucugcaaa guccuccacc ucgaaggcga aguaaacaaa      480

aucaagucag cccuccucuc caccaacaaa gccgucgucu cucucucaaa cggcguaucc      540

guccucacau ucaaaguccu cgaccucaaa aacuacaucg acaaacaacu ucuccccauc      600

cuaaacaaac aaucaugcuc cauccccaac cccgaaacag ucauggaauu ucaacaaaag      660

aacaaccgcc ucuuagaaau cacccgagaa uuuuccguca acgcgggagu cacaaccccc      720

guuucuacgu auaugcucac caacuccgaa cuccuuuccc ucauaaacga caugccaauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgaca acaauccuac      840

ucuauuaugu gcaucaucaa agaagaaguu cucgccuacg ucguccaacu accccucuac      900

ggcgugaucg acacccccug cuggaaacua cacaccucac cccucugcac caccaacacc      960

aaggaaggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcu     1020

ggcuccgucu cauucuuccc gcaagccgaa acuugcaaag uaugcuccaa cagaguauuc     1080

ugcgacacca ugaacucacu aacccucccu uccgaaguca accuuugcaa cguugacaua     1140

uucaacccaa aguacgauug caaaauuaug acauccaaaa cagaugucuc cuccuccguc     1200

aucacauccc ucggugccau uguaucaugc uacggaaaaa ccaaaugcac cgcauccaac     1260

aaaaacaaag gaaucaucaa aaccuucuca aacggcugcg auuacgucuc aaacaaagga     1320

gucgacacag ucuccgucgg aaacacccua uacuacguca acaaacaaga aggccaaucc     1380

cuguacguca aaggagaacc caucaucaac uucuacgacc cccucgucuu cccgagcgac     1440

gaguucgacg ccuccaucuc acaagucaau gaaaagauca accaaucccu ugccuucauc     1500

cggaaaucgg acgaacuccu acacaacgug aacgcuggaa aaucaaccac caacaucaug     1560

aucacaacca ucauuaucgu caucaucguc auacuccucu cccuaaucgc cgucggccuc     1620

cuccuguauu gcaaagcucg cuccaccccc gucacccugu ccaaagacca acucuccgga     1680

aucaacaaca ucgccuucuc aaacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6385
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6385
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6386
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6386
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcucca cccccgugac ccugagcaag     1740

gaccagcugu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6387
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6387
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6388
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6388
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggucaa caccugugac cuugaguaag     1740

gaucagcugu cugggauuaa caauaucgcu uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6389
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6389
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6390
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6390
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcagca caccggugac ccugucuaag     1740

gaucagcuuu ccggaauuaa caauaucgcg uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6391
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6391
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaaucu uaaaagcaaa ugcuauaacc acaauauuaa cagcaguaac auucuguuuu      240

gccuccggac aaaacauaac agaagaauuu uaucaaucaa caugcucugc aguauccaaa      300

gguuacuuag gcgcacuacg cacuggaugg uauacaucag uaauaacaau agaacuauca      360

aacauaaaag aaaauaaaug uaacgguacu gacgcaaaag ugaaacuaau uaaacaagaa      420

cucgacaaau acaaaaaugc uguaacagac cuacaaaugc uaaugugcuc aacacccgca      480

accggaucag gaucagccau agccuccgga gucgcaguau gcaaaguauu acaucuugaa      540

ggagaaguaa auaaaauaaa aucagcauua cuauccacaa auaaagccgu aguaucacua      600

ucaaacggug uauccguccu uacauucaaa guauuagauc uaaaaaacua cauagauaaa      660

caacuacuac ccaucuuaaa caaacaauca ugcucaauuc ccaacccaga aacagucaug      720

gaauuucaac aaaaaaacaa cagacucuua gaaauaacac gagaauuuuc aguaaacgca      780

ggaguaacca caccaguaag uacauacaug cucaccaacu cagaauuauu aucacuuauu      840

aacgacaugc caauuacaaa cgaccaaaaa aaauuaaugu caaacaaugu ccaaauuguu      900

agacaacaau cauacucuau aauguguaua auaaaagaag aaguacuagc uuacguaguu      960

caauuaccac uauauggcgu aauagauaca ccuugcugga aacuacauac aucuccauua     1020

uguacaacua acacaaaaga aggaucuaac auaugccuaa cacgcacaga ucgaggaugg     1080

uacugcgaua augcagguuc cguaucauuc uuuccacaag cagaaacaug uaaaguaugc     1140

ucaaacagag uauucuguga cacuaugaac uccuuaaccc uacccucaga agucaaucua     1200

ugcaacguug acauauuuaa cccaaaauac gacuguaaaa ucaugacauc uaaaacagac     1260

guaucaucau caguuauuac aucccuagga gcaauaguau cuugcuacgg aaaaacaaaa     1320

uguacagcau ccaacaaaaa caaaggaaua aucaaaacau ucucaaacgg cugcgacuac     1380

guaucaaaca aagguguaga cacaguauca guaggaaaua cuuuauauua cguaaauaaa     1440

caagaaggac aaucucuaua cguuaaaggc gaaccuauua uaaacuucua cgacccacuc     1500

guauucccuu cagacgaauu ugacgcaucu auaucccaag uuaacgaaaa aaucaaccaa     1560

ucauuagccu uuauaagaaa auccgacgaa uuauuacaua acgucaacgc uggaaaauca     1620

acaacuaaca uaaugauaac cacaauaaua auagucauca uaguuauauu acuaagucua     1680

auagccguag gccuccuacu uuauugcaaa gcaagaucaa caccaguaac auuauccaaa     1740

gaccaacuca gcggcauaaa caauauagcu uuuucaaacu agggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6392
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6392
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgcaaucaca accauacuaa cugcaguuac uuucugcuuc      240

gcauccggcc aaaacaucac cgaagaguuc uaccaaucaa ccugcuccgc agucuccaaa      300

ggauaccucg gagcccuucg caccggcugg uacaccuccg ucauaaccau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcaca gacgcgaaag ucaaacuuau caaacaagaa      420

cucgacaaau acaaaaacgc cgucaccgac cugcagaugc ucaugugcuc aacccccgcc      480

acaggaagcg gcucugcuau cgcuuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa gucagcccuc cucuccacca acaaagccgu cgucucucuc      600

ucaaacggcg uauccguccu cacauucaaa guccucgacc ucaaaaacua caucgacaaa      660

caacuucucc ccauccuaaa caaacaauca ugcuccaucc ccaaccccga aacagucaug      720

gaauuucaac aaaagaacaa ccgccucuua gaaaucaccc gagaauuuuc cgucaacgcg      780

ggagucacaa cccccguuuc uacguauaug cucaccaacu ccgaacuccu uucccucaua      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu ccaaaucguc      900

cgacaacaau ccuacucuau uaugugcauc aucaaagaag aaguucucgc cuacgucguc      960

caacuacccc ucuacggcgu gaucgacacc cccugcugga aacuacacac cucaccccuc     1020

ugcaccacca acaccaagga aggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgcuggcuc cgucucauuc uucccgcaag ccgaaacuug caaaguaugc     1140

uccaacagag uauucugcga caccaugaac ucacuaaccc ucccuuccga agucaaccuu     1200

ugcaacguug acauauucaa cccaaaguac gauugcaaaa uuaugacauc caaaacagau     1260

gucuccuccu ccgucaucac aucccucggu gccauuguau caugcuacgg aaaaaccaaa     1320

ugcaccgcau ccaacaaaaa caaaggaauc aucaaaaccu ucucaaacgg cugcgauuac     1380

gucucaaaca aaggagucga cacagucucc gucggaaaca cccuauacua cgucaacaaa     1440

caagaaggcc aaucccugua cgucaaagga gaacccauca ucaacuucua cgacccccuc     1500

gucuucccga gcgacgaguu cgacgccucc aucucacaag ucaaugaaaa gaucaaccaa     1560

ucccuugccu ucauccggaa aucggacgaa cuccuacaca acgugaacgc uggaaaauca     1620

accaccaaca ucaugaucac aaccaucauu aucgucauca ucgucauacu ccucucccua     1680

aucgccgucg gccuccuccu guauugcaaa gcucgcucca cccccgucac ccuguccaaa     1740

gaccaacucu ccggaaucaa caacaucgcc uucucaaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  6393
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6393
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6394
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6394
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcucca cccccgugac ccugagcaag     1740

gaccagcugu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6395
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6395
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6396
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6396
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggucaa caccugugac cuugaguaag     1740

gaucagcugu cugggauuaa caauaucgcu uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6397
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6397
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6398
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6398
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcagca caccggugac ccugucuaag     1740

gaucagcuuu ccggaauuaa caauaucgcg uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6399
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6399
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaaucu uaaaagcaaa ugcuauaacc acaauauuaa cagcaguaac auucuguuuu      240

gccuccggac aaaacauaac agaagaauuu uaucaaucaa caugcucugc aguauccaaa      300

gguuacuuag gcgcacuacg cacuggaugg uauacaucag uaauaacaau agaacuauca      360

aacauaaaag aaaauaaaug uaacgguacu gacgcaaaag ugaaacuaau uaaacaagaa      420

cucgacaaau acaaaaaugc uguaacagac cuacaaaugc uaaugugcuc aacacccgca      480

accggaucag gaucagccau agccuccgga gucgcaguau gcaaaguauu acaucuugaa      540

ggagaaguaa auaaaauaaa aucagcauua cuauccacaa auaaagccgu aguaucacua      600

ucaaacggug uauccguccu uacauucaaa guauuagauc uaaaaaacua cauagauaaa      660

caacuacuac ccaucuuaaa caaacaauca ugcucaauuc ccaacccaga aacagucaug      720

gaauuucaac aaaaaaacaa cagacucuua gaaauaacac gagaauuuuc aguaaacgca      780

ggaguaacca caccaguaag uacauacaug cucaccaacu cagaauuauu aucacuuauu      840

aacgacaugc caauuacaaa cgaccaaaaa aaauuaaugu caaacaaugu ccaaauuguu      900

agacaacaau cauacucuau aauguguaua auaaaagaag aaguacuagc uuacguaguu      960

caauuaccac uauauggcgu aauagauaca ccuugcugga aacuacauac aucuccauua     1020

uguacaacua acacaaaaga aggaucuaac auaugccuaa cacgcacaga ucgaggaugg     1080

uacugcgaua augcagguuc cguaucauuc uuuccacaag cagaaacaug uaaaguaugc     1140

ucaaacagag uauucuguga cacuaugaac uccuuaaccc uacccucaga agucaaucua     1200

ugcaacguug acauauuuaa cccaaaauac gacuguaaaa ucaugacauc uaaaacagac     1260

guaucaucau caguuauuac aucccuagga gcaauaguau cuugcuacgg aaaaacaaaa     1320

uguacagcau ccaacaaaaa caaaggaaua aucaaaacau ucucaaacgg cugcgacuac     1380

guaucaaaca aagguguaga cacaguauca guaggaaaua cuuuauauua cguaaauaaa     1440

caagaaggac aaucucuaua cguuaaaggc gaaccuauua uaaacuucua cgacccacuc     1500

guauucccuu cagacgaauu ugacgcaucu auaucccaag uuaacgaaaa aaucaaccaa     1560

ucauuagccu uuauaagaaa auccgacgaa uuauuacaua acgucaacgc uggaaaauca     1620

acaacuaaca uaaugauaac cacaauaaua auagucauca uaguuauauu acuaagucua     1680

auagccguag gccuccuacu uuauugcaaa gcaagaucaa caccaguaac auuauccaaa     1740

gaccaacuca gcggcauaaa caauauagcu uuuucaaacu agggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6400
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6400
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgcaaucaca accauacuaa cugcaguuac uuucugcuuc      240

gcauccggcc aaaacaucac cgaagaguuc uaccaaucaa ccugcuccgc agucuccaaa      300

ggauaccucg gagcccuucg caccggcugg uacaccuccg ucauaaccau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcaca gacgcgaaag ucaaacuuau caaacaagaa      420

cucgacaaau acaaaaacgc cgucaccgac cugcagaugc ucaugugcuc aacccccgcc      480

acaggaagcg gcucugcuau cgcuuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa gucagcccuc cucuccacca acaaagccgu cgucucucuc      600

ucaaacggcg uauccguccu cacauucaaa guccucgacc ucaaaaacua caucgacaaa      660

caacuucucc ccauccuaaa caaacaauca ugcuccaucc ccaaccccga aacagucaug      720

gaauuucaac aaaagaacaa ccgccucuua gaaaucaccc gagaauuuuc cgucaacgcg      780

ggagucacaa cccccguuuc uacguauaug cucaccaacu ccgaacuccu uucccucaua      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu ccaaaucguc      900

cgacaacaau ccuacucuau uaugugcauc aucaaagaag aaguucucgc cuacgucguc      960

caacuacccc ucuacggcgu gaucgacacc cccugcugga aacuacacac cucaccccuc     1020

ugcaccacca acaccaagga aggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgcuggcuc cgucucauuc uucccgcaag ccgaaacuug caaaguaugc     1140

uccaacagag uauucugcga caccaugaac ucacuaaccc ucccuuccga agucaaccuu     1200

ugcaacguug acauauucaa cccaaaguac gauugcaaaa uuaugacauc caaaacagau     1260

gucuccuccu ccgucaucac aucccucggu gccauuguau caugcuacgg aaaaaccaaa     1320

ugcaccgcau ccaacaaaaa caaaggaauc aucaaaaccu ucucaaacgg cugcgauuac     1380

gucucaaaca aaggagucga cacagucucc gucggaaaca cccuauacua cgucaacaaa     1440

caagaaggcc aaucccugua cgucaaagga gaacccauca ucaacuucua cgacccccuc     1500

gucuucccga gcgacgaguu cgacgccucc aucucacaag ucaaugaaaa gaucaaccaa     1560

ucccuugccu ucauccggaa aucggacgaa cuccuacaca acgugaacgc uggaaaauca     1620

accaccaaca ucaugaucac aaccaucauu aucgucauca ucgucauacu ccucucccua     1680

aucgccgucg gccuccuccu guauugcaaa gcucgcucca cccccgucac ccuguccaaa     1740

gaccaacucu ccggaaucaa caacaucgcc uucucaaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  6401
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6401
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6402
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6402
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcucca cccccgugac ccugagcaag     1740

gaccagcugu ccggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6403
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6403
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6404
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6404
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggucaa caccugugac cuugaguaag     1740

gaucagcugu cugggauuaa caauaucgcu uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6405
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6405
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6406
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6406
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcagca caccggugac ccugucuaag     1740

gaucagcuuu ccggaauuaa caauaucgcg uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6407
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6407
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaaucu uaaaagcaaa ugcuauaacc acaauauuaa cagcaguaac auucuguuuu      240

gccuccggac aaaacauaac agaagaauuu uaucaaucaa caugcucugc aguauccaaa      300

gguuacuuag gcgcacuacg cacuggaugg uauacaucag uaauaacaau agaacuauca      360

aacauaaaag aaaauaaaug uaacgguacu gacgcaaaag ugaaacuaau uaaacaagaa      420

cucgacaaau acaaaaaugc uguaacagac cuacaaaugc uaaugugcuc aacacccgca      480

accggaucag gaucagccau agccuccgga gucgcaguau gcaaaguauu acaucuugaa      540

ggagaaguaa auaaaauaaa aucagcauua cuauccacaa auaaagccgu aguaucacua      600

ucaaacggug uauccguccu uacauucaaa guauuagauc uaaaaaacua cauagauaaa      660

caacuacuac ccaucuuaaa caaacaauca ugcucaauuc ccaacccaga aacagucaug      720

gaauuucaac aaaaaaacaa cagacucuua gaaauaacac gagaauuuuc aguaaacgca      780

ggaguaacca caccaguaag uacauacaug cucaccaacu cagaauuauu aucacuuauu      840

aacgacaugc caauuacaaa cgaccaaaaa aaauuaaugu caaacaaugu ccaaauuguu      900

agacaacaau cauacucuau aauguguaua auaaaagaag aaguacuagc uuacguaguu      960

caauuaccac uauauggcgu aauagauaca ccuugcugga aacuacauac aucuccauua     1020

uguacaacua acacaaaaga aggaucuaac auaugccuaa cacgcacaga ucgaggaugg     1080

uacugcgaua augcagguuc cguaucauuc uuuccacaag cagaaacaug uaaaguaugc     1140

ucaaacagag uauucuguga cacuaugaac uccuuaaccc uacccucaga agucaaucua     1200

ugcaacguug acauauuuaa cccaaaauac gacuguaaaa ucaugacauc uaaaacagac     1260

guaucaucau caguuauuac aucccuagga gcaauaguau cuugcuacgg aaaaacaaaa     1320

uguacagcau ccaacaaaaa caaaggaaua aucaaaacau ucucaaacgg cugcgacuac     1380

guaucaaaca aagguguaga cacaguauca guaggaaaua cuuuauauua cguaaauaaa     1440

caagaaggac aaucucuaua cguuaaaggc gaaccuauua uaaacuucua cgacccacuc     1500

guauucccuu cagacgaauu ugacgcaucu auaucccaag uuaacgaaaa aaucaaccaa     1560

ucauuagccu uuauaagaaa auccgacgaa uuauuacaua acgucaacgc uggaaaauca     1620

acaacuaaca uaaugauaac cacaauaaua auagucauca uaguuauauu acuaagucua     1680

auagccguag gccuccuacu uuauugcaaa gcaagaucaa caccaguaac auuauccaaa     1740

gaccaacuca gcggcauaaa caauauagcu uuuucaaacu agggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6408
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6408
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgcaaucaca accauacuaa cugcaguuac uuucugcuuc      240

gcauccggcc aaaacaucac cgaagaguuc uaccaaucaa ccugcuccgc agucuccaaa      300

ggauaccucg gagcccuucg caccggcugg uacaccuccg ucauaaccau cgaacucuca      360

aacauaaaag aaaacaaaug caacggcaca gacgcgaaag ucaaacuuau caaacaagaa      420

cucgacaaau acaaaaacgc cgucaccgac cugcagaugc ucaugugcuc aacccccgcc      480

acaggaagcg gcucugcuau cgcuuccggc gucgccgucu gcaaaguccu ccaccucgaa      540

ggcgaaguaa acaaaaucaa gucagcccuc cucuccacca acaaagccgu cgucucucuc      600

ucaaacggcg uauccguccu cacauucaaa guccucgacc ucaaaaacua caucgacaaa      660

caacuucucc ccauccuaaa caaacaauca ugcuccaucc ccaaccccga aacagucaug      720

gaauuucaac aaaagaacaa ccgccucuua gaaaucaccc gagaauuuuc cgucaacgcg      780

ggagucacaa cccccguuuc uacguauaug cucaccaacu ccgaacuccu uucccucaua      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu caaacaacgu ccaaaucguc      900

cgacaacaau ccuacucuau uaugugcauc aucaaagaag aaguucucgc cuacgucguc      960

caacuacccc ucuacggcgu gaucgacacc cccugcugga aacuacacac cucaccccuc     1020

ugcaccacca acaccaagga aggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgcuggcuc cgucucauuc uucccgcaag ccgaaacuug caaaguaugc     1140

uccaacagag uauucugcga caccaugaac ucacuaaccc ucccuuccga agucaaccuu     1200

ugcaacguug acauauucaa cccaaaguac gauugcaaaa uuaugacauc caaaacagau     1260

gucuccuccu ccgucaucac aucccucggu gccauuguau caugcuacgg aaaaaccaaa     1320

ugcaccgcau ccaacaaaaa caaaggaauc aucaaaaccu ucucaaacgg cugcgauuac     1380

gucucaaaca aaggagucga cacagucucc gucggaaaca cccuauacua cgucaacaaa     1440

caagaaggcc aaucccugua cgucaaagga gaacccauca ucaacuucua cgacccccuc     1500

gucuucccga gcgacgaguu cgacgccucc aucucacaag ucaaugaaaa gaucaaccaa     1560

ucccuugccu ucauccggaa aucggacgaa cuccuacaca acgugaacgc uggaaaauca     1620

accaccaaca ucaugaucac aaccaucauu aucgucauca ucgucauacu ccucucccua     1680

aucgccgucg gccuccuccu guauugcaaa gcucgcucca cccccgucac ccuguccaaa     1740

gaccaacucu ccggaaucaa caacaucgcc uucucaaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6409
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6409
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6410
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6410
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      480

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc      960

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu ccacccccgu gacccugagc     1620

aaggaccagc uguccggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6411
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6411
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6412
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6412
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      360

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      420

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      480

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      540

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      660

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      720

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      780

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua      840

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu      900

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg      960

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1020

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1080

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1200

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1260

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1320

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1380

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1440

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1500

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1560

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu caacaccugu gaccuugagu     1620

aaggaucagc ugucugggau uaacaauauc gcuuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6413
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6413
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6414
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6414
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      360

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      420

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      480

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      540

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      660

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      720

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug      840

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu      900

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc      960

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1020

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1080

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1200

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1260

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1380

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1440

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1500

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1560

cuuaucgccg uggggcugcu ccuguacugc aaagcucgca gcacaccggu gacccugucu     1620

aaggaucagc uuuccggaau uaacaauauc gcguucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6415
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6415
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuauuaa ucuuaaaagc aaaugcuaua accacaauau uaacagcagu aacauucugu      120

uuugccuccg gacaaaacau aacagaagaa uuuuaucaau caacaugcuc ugcaguaucc      180

aaagguuacu uaggcgcacu acgcacugga ugguauacau caguaauaac aauagaacua      240

ucaaacauaa aagaaaauaa auguaacggu acugacgcaa aagugaaacu aauuaaacaa      300

gaacucgaca aauacaaaaa ugcuguaaca gaccuacaaa ugcuaaugug cucaacaccc      360

gcaaccggau caggaucagc cauagccucc ggagucgcag uaugcaaagu auuacaucuu      420

gaaggagaag uaaauaaaau aaaaucagca uuacuaucca caaauaaagc cguaguauca      480

cuaucaaacg guguauccgu ccuuacauuc aaaguauuag aucuaaaaaa cuacauagau      540

aaacaacuac uacccaucuu aaacaaacaa ucaugcucaa uucccaaccc agaaacaguc      600

auggaauuuc aacaaaaaaa caacagacuc uuagaaauaa cacgagaauu uucaguaaac      660

gcaggaguaa ccacaccagu aaguacauac augcucacca acucagaauu auuaucacuu      720

auuaacgaca ugccaauuac aaacgaccaa aaaaaauuaa ugucaaacaa uguccaaauu      780

guuagacaac aaucauacuc uauaaugugu auaauaaaag aagaaguacu agcuuacgua      840

guucaauuac cacuauaugg cguaauagau acaccuugcu ggaaacuaca uacaucucca      900

uuauguacaa cuaacacaaa agaaggaucu aacauaugcc uaacacgcac agaucgagga      960

ugguacugcg auaaugcagg uuccguauca uucuuuccac aagcagaaac auguaaagua     1020

ugcucaaaca gaguauucug ugacacuaug aacuccuuaa cccuacccuc agaagucaau     1080

cuaugcaacg uugacauauu uaacccaaaa uacgacugua aaaucaugac aucuaaaaca     1140

gacguaucau caucaguuau uacaucccua ggagcaauag uaucuugcua cggaaaaaca     1200

aaauguacag cauccaacaa aaacaaagga auaaucaaaa cauucucaaa cggcugcgac     1260

uacguaucaa acaaaggugu agacacagua ucaguaggaa auacuuuaua uuacguaaau     1320

aaacaagaag gacaaucucu auacguuaaa ggcgaaccua uuauaaacuu cuacgaccca     1380

cucguauucc cuucagacga auuugacgca ucuauauccc aaguuaacga aaaaaucaac     1440

caaucauuag ccuuuauaag aaaauccgac gaauuauuac auaacgucaa cgcuggaaaa     1500

ucaacaacua acauaaugau aaccacaaua auaauaguca ucauaguuau auuacuaagu     1560

cuaauagccg uaggccuccu acuuuauugc aaagcaagau caacaccagu aacauuaucc     1620

aaagaccaac ucagcggcau aaacaauaua gcuuuuucaa acuagggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6416
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6416
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgcaauc acaaccauac uaacugcagu uacuuucugc      120

uucgcauccg gccaaaacau caccgaagag uucuaccaau caaccugcuc cgcagucucc      180

aaaggauacc ucggagcccu ucgcaccggc ugguacaccu ccgucauaac caucgaacuc      240

ucaaacauaa aagaaaacaa augcaacggc acagacgcga aagucaaacu uaucaaacaa      300

gaacucgaca aauacaaaaa cgccgucacc gaccugcaga ugcucaugug cucaaccccc      360

gccacaggaa gcggcucugc uaucgcuucc ggcgucgccg ucugcaaagu ccuccaccuc      420

gaaggcgaag uaaacaaaau caagucagcc cuccucucca ccaacaaagc cgucgucucu      480

cucucaaacg gcguauccgu ccucacauuc aaaguccucg accucaaaaa cuacaucgac      540

aaacaacuuc uccccauccu aaacaaacaa ucaugcucca uccccaaccc cgaaacaguc      600

auggaauuuc aacaaaagaa caaccgccuc uuagaaauca cccgagaauu uuccgucaac      660

gcgggaguca caacccccgu uucuacguau augcucacca acuccgaacu ccuuucccuc      720

auaaacgaca ugccaaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      780

guccgacaac aauccuacuc uauuaugugc aucaucaaag aagaaguucu cgccuacguc      840

guccaacuac cccucuacgg cgugaucgac acccccugcu ggaaacuaca caccucaccc      900

cucugcacca ccaacaccaa ggaaggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgcugg cuccgucuca uucuucccgc aagccgaaac uugcaaagua     1020

ugcuccaaca gaguauucug cgacaccaug aacucacuaa cccucccuuc cgaagucaac     1080

cuuugcaacg uugacauauu caacccaaag uacgauugca aaauuaugac auccaaaaca     1140

gaugucuccu ccuccgucau cacaucccuc ggugccauug uaucaugcua cggaaaaacc     1200

aaaugcaccg cauccaacaa aaacaaagga aucaucaaaa ccuucucaaa cggcugcgau     1260

uacgucucaa acaaaggagu cgacacaguc uccgucggaa acacccuaua cuacgucaac     1320

aaacaagaag gccaaucccu guacgucaaa ggagaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc cgagcgacga guucgacgcc uccaucucac aagucaauga aaagaucaac     1440

caaucccuug ccuucauccg gaaaucggac gaacuccuac acaacgugaa cgcuggaaaa     1500

ucaaccacca acaucaugau cacaaccauc auuaucguca ucaucgucau acuccucucc     1560

cuaaucgccg ucggccuccu ccuguauugc aaagcucgcu ccacccccgu cacccugucc     1620

aaagaccaac ucuccggaau caacaacauc gccuucucaa acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6417
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6417
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag acggugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugugca     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc cuguccaagg     1620

accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6418
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6418
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc acccccgcca      360

ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug caccuggagg      420

gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug gucagccugu      480

ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac aucgacaagc      540

agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag accgugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug agccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac cggggcuggu      960

acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag gucaaccucu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac gucaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug cucagccuga     1560

ucgccguggg gcugcuccug uacugcaagg cccgcuccac ccccgugacc cugagcaagg     1620

accagcuguc cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6419
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6419
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag accgucaugg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc cucuccaagg     1620

accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6420
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6420
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc acacccgcca      360

ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug cacuuggagg      420

gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug gucucccugu      480

cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac auugacaaac      540

agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa accgugaugg      600

aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu gucaacgcgg      660

gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug uccuugauaa      720

acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc caaaucguuc      780

gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca uauguagugc      840

aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca ucuccucuuu      900

gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac cguggguggu      960

acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu aagguuugcu     1020

cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa gucaaucugu     1080

guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu aaaacagaug     1140

uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc aagaccaaau     1200

gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga ugugacuaug     1260

ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau guuaacaaac     1320

aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau gauccgcugg     1380

uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa auuaaccagu     1440

cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg ggcaagagca     1500

caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua cugucccuaa     1560

ucgccgucgg ccuccugcuu uacugcaaag cacggucaac accugugacc uugaguaagg     1620

aucagcuguc ugggauuaac aauaucgcuu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6421
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6421
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag accgugaugg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugugca     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc cugagcaagg     1620

accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6422
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6422
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc acccccgcca      360

caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug caccucgagg      420

gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc gugucucugu      480

ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac auugacaaac      540

agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa accgugaugg      600

aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc gugaacgccg      660

gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug agccucauua      720

acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug caaaucguga      780

gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu uaugugguuc      840

agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg uccccucugu      900

gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac cgcggcuggu      960

acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu aaggugugca     1020

gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa gugaaucugu     1080

guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc aaaacagaug     1140

ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc aagacaaaau     1200

gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga ugugacuaug     1260

uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau guuaacaaac     1320

aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau gauccucugg     1380

ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa auuaaccagu     1440

cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc ggcaagagca     1500

caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc cugucccuua     1560

ucgccguggg gcugcuccug uacugcaaag cucgcagcac accggugacc cugucuaagg     1620

aucagcuuuc cggaauuaac aauaucgcgu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6423
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6423
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uauuaaucuu aaaagcaaau gcuauaacca caauauuaac agcaguaaca uucuguuuug      120

ccuccggaca aaacauaaca gaagaauuuu aucaaucaac augcucugca guauccaaag      180

guuacuuagg cgcacuacgc acuggauggu auacaucagu aauaacaaua gaacuaucaa      240

acauaaaaga aaauaaaugu aacgguacug acgcaaaagu gaaacuaauu aaacaagaac      300

ucgacaaaua caaaaaugcu guaacagacc uacaaaugcu aaugugcuca acacccgcaa      360

ccggaucagg aucagccaua gccuccggag ucgcaguaug caaaguauua caucuugaag      420

gagaaguaaa uaaaauaaaa ucagcauuac uauccacaaa uaaagccgua guaucacuau      480

caaacggugu auccguccuu acauucaaag uauuagaucu aaaaaacuac auagauaaac      540

aacuacuacc caucuuaaac aaacaaucau gcucaauucc caacccagaa acagucaugg      600

aauuucaaca aaaaaacaac agacucuuag aaauaacacg agaauuuuca guaaacgcag      660

gaguaaccac accaguaagu acauacaugc ucaccaacuc agaauuauua ucacuuauua      720

acgacaugcc aauuacaaac gaccaaaaaa aauuaauguc aaacaauguc caaauuguua      780

gacaacaauc auacucuaua auguguauaa uaaaagaaga aguacuagcu uacguaguuc      840

aauuaccacu auauggcgua auagauacac cuugcuggaa acuacauaca ucuccauuau      900

guacaacuaa cacaaaagaa ggaucuaaca uaugccuaac acgcacagau cgaggauggu      960

acugcgauaa ugcagguucc guaucauucu uuccacaagc agaaacaugu aaaguaugcu     1020

caaacagagu auucugugac acuaugaacu ccuuaacccu acccucagaa gucaaucuau     1080

gcaacguuga cauauuuaac ccaaaauacg acuguaaaau caugacaucu aaaacagacg     1140

uaucaucauc aguuauuaca ucccuaggag caauaguauc uugcuacgga aaaacaaaau     1200

guacagcauc caacaaaaac aaaggaauaa ucaaaacauu cucaaacggc ugcgacuacg     1260

uaucaaacaa agguguagac acaguaucag uaggaaauac uuuauauuac guaaauaaac     1320

aagaaggaca aucucuauac guuaaaggcg aaccuauuau aaacuucuac gacccacucg     1380

uauucccuuc agacgaauuu gacgcaucua uaucccaagu uaacgaaaaa aucaaccaau     1440

cauuagccuu uauaagaaaa uccgacgaau uauuacauaa cgucaacgcu ggaaaaucaa     1500

caacuaacau aaugauaacc acaauaauaa uagucaucau aguuauauua cuaagucuaa     1560

uagccguagg ccuccuacuu uauugcaaag caagaucaac accaguaaca uuauccaaag     1620

accaacucag cggcauaaac aauauagcuu uuucaaacua gggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6424
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6424
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu caaagccaac gcaaucacaa ccauacuaac ugcaguuacu uucugcuucg      120

cauccggcca aaacaucacc gaagaguucu accaaucaac cugcuccgca gucuccaaag      180

gauaccucgg agcccuucgc accggcuggu acaccuccgu cauaaccauc gaacucucaa      240

acauaaaaga aaacaaaugc aacggcacag acgcgaaagu caaacuuauc aaacaagaac      300

ucgacaaaua caaaaacgcc gucaccgacc ugcagaugcu caugugcuca acccccgcca      360

caggaagcgg cucugcuauc gcuuccggcg ucgccgucug caaaguccuc caccucgaag      420

gcgaaguaaa caaaaucaag ucagcccucc ucuccaccaa caaagccguc gucucucucu      480

caaacggcgu auccguccuc acauucaaag uccucgaccu caaaaacuac aucgacaaac      540

aacuucuccc cauccuaaac aaacaaucau gcuccauccc caaccccgaa acagucaugg      600

aauuucaaca aaagaacaac cgccucuuag aaaucacccg agaauuuucc gucaacgcgg      660

gagucacaac ccccguuucu acguauaugc ucaccaacuc cgaacuccuu ucccucauaa      720

acgacaugcc aaucaccaac gaccaaaaga aacucauguc aaacaacguc caaaucgucc      780

gacaacaauc cuacucuauu augugcauca ucaaagaaga aguucucgcc uacgucgucc      840

aacuaccccu cuacggcgug aucgacaccc ccugcuggaa acuacacacc ucaccccucu      900

gcaccaccaa caccaaggaa ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgcuggcucc gucucauucu ucccgcaagc cgaaacuugc aaaguaugcu     1020

ccaacagagu auucugcgac accaugaacu cacuaacccu cccuuccgaa gucaaccuuu     1080

gcaacguuga cauauucaac ccaaaguacg auugcaaaau uaugacaucc aaaacagaug     1140

ucuccuccuc cgucaucaca ucccucggug ccauuguauc augcuacgga aaaaccaaau     1200

gcaccgcauc caacaaaaac aaaggaauca ucaaaaccuu cucaaacggc ugcgauuacg     1260

ucucaaacaa aggagucgac acagucuccg ucggaaacac ccuauacuac gucaacaaac     1320

aagaaggcca aucccuguac gucaaaggag aacccaucau caacuucuac gacccccucg     1380

ucuucccgag cgacgaguuc gacgccucca ucucacaagu caaugaaaag aucaaccaau     1440

cccuugccuu cauccggaaa ucggacgaac uccuacacaa cgugaacgcu ggaaaaucaa     1500

ccaccaacau caugaucaca accaucauua ucgucaucau cgucauacuc cucucccuaa     1560

ucgccgucgg ccuccuccug uauugcaaag cucgcuccac ccccgucacc cuguccaaag     1620

accaacucuc cggaaucaac aacaucgccu ucucaaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  6425
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6425
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagaug      300

cugaugugcu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaaccccg agacggugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugug cagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga acaaggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu acgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccggagc     1560

acgcccguca cccuguccaa ggaccagcug agcggcauca acaacaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6426
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt1)

<400>  6426
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagaug      300

cucaugugca gcacccccgc caccgggucc ggcagcgcca ucgccuccgg cguggcggug      360

ugcaaggucc ugcaccugga gggggaggug aacaagauca agagcgcccu ccuguccacc      420

aacaaggccg uggucagccu guccaacggc gugagcgugc ucacguucaa gguccuggac      480

cugaagaacu acaucgacaa gcagcuccug ccgauccuga acaagcaguc cugcagcauc      540

cccaaccccg agaccgugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcugaccaac      660

uccgagcucc ugagccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcugccc cucuacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacacgaagg aggggagcaa caucugccuc      900

acccgcaccg accggggcug guacugcgac aacgcgggcu ccgugagcuu cuucccgcag      960

gccgagaccu gcaaggucug cuccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cugcccuccg aggucaaccu cugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga acaaggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccuguacu acgucaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccuggcg uucauccgga aguccgacga gcuccugcac     1440

aacgugaacg ccggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc ugcucagccu gaucgccgug gggcugcucc uguacugcaa ggcccgcucc     1560

acccccguga cccugagcaa ggaccagcug uccggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6427
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt2)

<400>  6427
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagaug      300

cucaugugcu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaaccccg agaccgucau ggaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucug cuccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga acaagggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu acgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcucc     1560

acccccguca cccucuccaa ggaccagcuc uccggcauca acaacaucgc cuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6428
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt3)

<400>  6428
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga ccugcagaug      300

cuuauguguu ccacacccgc caccgggucu ggaucggcua uagcaucagg cguggccguc      360

ugcaaggugc ugcacuugga gggugagguu aacaaaauca agagcgcucu ccugaguacg      420

aauaaagccg uggucucccu gucuaacggg gugagcguac ucacuuuuaa gguuuuagau      480

cugaagaauu acauugacaa acagcuuuug ccuauccuga acaagcaauc cuguucaauu      540

ccaaauccgg aaaccgugau ggaguuccag cagaaaaaca auaggcuacu cgaaaucaca      600

cgggaguuua gugucaacgc gggagugacu acccccguga gcacauauau gcugaccaau      660

ucugagcuuc uguccuugau aaacgauaug ccuauuacga acgaccagaa gaaacucaug      720

ucaaauaacg uccaaaucgu ucgccagcag agcuacagua uuaugugcau caucaaggaa      780

gaggugcugg cauauguagu gcaguuacca cuguacggcg ucauugauac ucccuguugg      840

aaacuccaua caucuccucu uugcaccacu aauacaaagg aaggcuccaa cauaugucug      900

acccgaacgg accgugggug guacugcgau aaugccggaa gcgugucguu cuuuccacaa      960

gcugagaccu guaagguuug cucuaacaga guguucugcg acacaaugaa cuccuugacu     1020

cuacccucag aagucaaucu guguaaugug gauaucuuua acccuaaaua ugacugcaag     1080

auuaugacca guaaaacaga uguaagcucc ucuguuauca cuagccucgg ugccauagug     1140

ucauguuacg gcaagaccaa augcacagca aguaauaaga acaaggggau uaucaaaacc     1200

uucuccaaug gaugugacua ugucagcaac aagggcgugg acacugucuc uguggguaau     1260

acgcuguacu auguuaacaa acaggagggg cagucacuuu acgugaaggg agagccaauc     1320

auuaacuuuu augauccgcu gguauucccc agugacgaau uugaugcuag caucucccaa     1380

gucaaugaga aaauuaacca gucuuuggcc uucauaagga agucggacga acuccugcac     1440

aaugugaacg cgggcaagag cacaaccaau aucaugauua cuaccaucau cauuguuaua     1500

aucgugauuu uacugucccu aaucgccguc ggccuccugc uuuacugcaa agcacgguca     1560

acaccuguga ccuugaguaa ggaucagcug ucugggauua acaauaucgc uuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6429
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt4)

<400>  6429
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagaug      300

cugaugugca gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaaccccg agaccgugau ggaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugug cagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acaagggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu acgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagaagc     1560

acccccguga cccugagcaa ggaccagcug agcggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6430
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt5)

<400>  6430
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaauaaau gcaacgggac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga ccuccagaug      300

cugaugugua gcacccccgc cacaggaucc ggcucugcua uugccagcgg ggucgcggug      360

ugcaagguuc ugcaccucga gggagaggug aacaaaauca aguccgcccu gcuuagcacc      420

aauaaagcug ucgugucucu guccaacggc guuagcgugc ucacauuuaa gguccuggau      480

cuuaagaauu acauugacaa acagcugcuc ccuauccuga acaagcaauc uuguuccauu      540

ccgaaucccg aaaccgugau ggaguuccag cagaaaaaca aucggcugcu cgaaaucacg      600

cgcgaguuua gcgugaacgc cggcgucaca accccuguuu cuacauauau gcugaccaau      660

uccgagcuuc ugagccucau uaacgauaug cccaucacca acgaccagaa gaaacugaug      720

uccaauaacg ugcaaaucgu gagacagcag ucuuacagca uuaugugcau cauuaaggaa      780

gagguccuug cuuauguggu ucagcugccu cucuacgggg ugaucgauac acccuguugg      840

aaacugcaua cguccccucu gugcaccaca aauaccaagg aaggaagcaa cauuugucuc      900

acacggaccg accgcggcug guacugcgau aaugccgggu cugucuccuu cuuuccgcaa      960

gcggagacgu guaaggugug cagcaacaga guuuucugcg acacaaugaa cucucugacc     1020

cuucccagcg aagugaaucu guguaauguc gauaucuuua acccuaaaua ugacugcaag     1080

aucaugaccu ccaaaacaga ugugucuagc uccgucauua ccagccucgg agccaucgug     1140

ucuuguuacg gcaagacaaa augcacggcu uccaauaaga acaaggggau uaucaaaacc     1200

uucagcaaug gaugugacua uguuucuaac aagggcgugg acacagucuc cgugggcaau     1260

acccuguacu auguuaacaa acaggagggg cagagccuuu acgugaaggg agagcccauu     1320

aucaacuuuu augauccucu ggucuucccc uccgacgaau uugaugccuc uaucagccaa     1380

gugaaugaga aaauuaacca gucccucgcu uucauccgga agucugacga acugcugcac     1440

aaugugaacg ccggcaagag cacaaccaau auuaugauca cgaccauuau cauuguuauc     1500

aucgucauuc uccugucccu uaucgccgug gggcugcucc uguacugcaa agcucgcagc     1560

acaccgguga cccugucuaa ggaucagcuu uccggaauua acaauaucgc guucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6431
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt6)

<400>  6431
gggagaaagc uuaccaugga acuauuaauc uuaaaagcaa augcuauaac cacaauauua       60

acagcaguaa cauucuguuu ugccuccgga caaaacauaa cagaagaauu uuaucaauca      120

acaugcucug caguauccaa agguuacuua ggcgcacuac gcacuggaug guauacauca      180

guaauaacaa uagaacuauc aaacauaaaa gaaaauaaau guaacgguac ugacgcaaaa      240

gugaaacuaa uuaaacaaga acucgacaaa uacaaaaaug cuguaacaga ccuacaaaug      300

cuaaugugcu caacacccgc aaccggauca ggaucagcca uagccuccgg agucgcagua      360

ugcaaaguau uacaucuuga aggagaagua aauaaaauaa aaucagcauu acuauccaca      420

aauaaagccg uaguaucacu aucaaacggu guauccgucc uuacauucaa aguauuagau      480

cuaaaaaacu acauagauaa acaacuacua cccaucuuaa acaaacaauc augcucaauu      540

cccaacccag aaacagucau ggaauuucaa caaaaaaaca acagacucuu agaaauaaca      600

cgagaauuuu caguaaacgc aggaguaacc acaccaguaa guacauacau gcucaccaac      660

ucagaauuau uaucacuuau uaacgacaug ccaauuacaa acgaccaaaa aaaauuaaug      720

ucaaacaaug uccaaauugu uagacaacaa ucauacucua uaauguguau aauaaaagaa      780

gaaguacuag cuuacguagu ucaauuacca cuauauggcg uaauagauac accuugcugg      840

aaacuacaua caucuccauu auguacaacu aacacaaaag aaggaucuaa cauaugccua      900

acacgcacag aucgaggaug guacugcgau aaugcagguu ccguaucauu cuuuccacaa      960

gcagaaacau guaaaguaug cucaaacaga guauucugug acacuaugaa cuccuuaacc     1020

cuacccucag aagucaaucu augcaacguu gacauauuua acccaaaaua cgacuguaaa     1080

aucaugacau cuaaaacaga cguaucauca ucaguuauua caucccuagg agcaauagua     1140

ucuugcuacg gaaaaacaaa auguacagca uccaacaaaa acaaaggaau aaucaaaaca     1200

uucucaaacg gcugcgacua cguaucaaac aaagguguag acacaguauc aguaggaaau     1260

acuuuauauu acguaaauaa acaagaagga caaucucuau acguuaaagg cgaaccuauu     1320

auaaacuucu acgacccacu cguauucccu ucagacgaau uugacgcauc uauaucccaa     1380

guuaacgaaa aaaucaacca aucauuagcc uuuauaagaa aauccgacga auuauuacau     1440

aacgucaacg cuggaaaauc aacaacuaac auaaugauaa ccacaauaau aauagucauc     1500

auaguuauau uacuaagucu aauagccgua ggccuccuac uuuauugcaa agcaagauca     1560

acaccaguaa cauuauccaa agaccaacuc agcggcauaa acaauauagc uuuuucaaac     1620

uagggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6432
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut6 (opt11)

<400>  6432
gggagaaagc uuaccaugga acuccucauc cucaaagcca acgcaaucac aaccauacua       60

acugcaguua cuuucugcuu cgcauccggc caaaacauca ccgaagaguu cuaccaauca      120

accugcuccg cagucuccaa aggauaccuc ggagcccuuc gcaccggcug guacaccucc      180

gucauaacca ucgaacucuc aaacauaaaa gaaaacaaau gcaacggcac agacgcgaaa      240

gucaaacuua ucaaacaaga acucgacaaa uacaaaaacg ccgucaccga ccugcagaug      300

cucaugugcu caacccccgc cacaggaagc ggcucugcua ucgcuuccgg cgucgccguc      360

ugcaaagucc uccaccucga aggcgaagua aacaaaauca agucagcccu ccucuccacc      420

aacaaagccg ucgucucucu cucaaacggc guauccgucc ucacauucaa aguccucgac      480

cucaaaaacu acaucgacaa acaacuucuc cccauccuaa acaaacaauc augcuccauc      540

cccaaccccg aaacagucau ggaauuucaa caaaagaaca accgccucuu agaaaucacc      600

cgagaauuuu ccgucaacgc gggagucaca acccccguuu cuacguauau gcucaccaac      660

uccgaacucc uuucccucau aaacgacaug ccaaucacca acgaccaaaa gaaacucaug      720

ucaaacaacg uccaaaucgu ccgacaacaa uccuacucua uuaugugcau caucaaagaa      780

gaaguucucg ccuacgucgu ccaacuaccc cucuacggcg ugaucgacac ccccugcugg      840

aaacuacaca ccucaccccu cugcaccacc aacaccaagg aaggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgcuggcu ccgucucauu cuucccgcaa      960

gccgaaacuu gcaaaguaug cuccaacaga guauucugcg acaccaugaa cucacuaacc     1020

cucccuuccg aagucaaccu uugcaacguu gacauauuca acccaaagua cgauugcaaa     1080

auuaugacau ccaaaacaga ugucuccucc uccgucauca caucccucgg ugccauugua     1140

ucaugcuacg gaaaaaccaa augcaccgca uccaacaaaa acaaaggaau caucaaaacc     1200

uucucaaacg gcugcgauua cgucucaaac aaaggagucg acacagucuc cgucggaaac     1260

acccuauacu acgucaacaa acaagaaggc caaucccugu acgucaaagg agaacccauc     1320

aucaacuucu acgacccccu cgucuucccg agcgacgagu ucgacgccuc caucucacaa     1380

gucaaugaaa agaucaacca aucccuugcc uucauccgga aaucggacga acuccuacac     1440

aacgugaacg cuggaaaauc aaccaccaac aucaugauca caaccaucau uaucgucauc     1500

aucgucauac uccucucccu aaucgccguc ggccuccucc uguauugcaa agcucgcucc     1560

acccccguca cccuguccaa agaccaacuc uccggaauca acaacaucgc cuucucaaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  6433
<211>  514
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6433

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Met Leu 
                85                  90                  95      


Met Cys Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Pro 
                165                 170                 175     


Asn Pro Glu Thr Val Met Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Cys Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Lys Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Tyr Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg 
        


<210>  6434
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6434
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agaugcugau gugcuccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa ccccgagacg      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugugcagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaacaag gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc gguga                     1545


<210>  6435
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6435
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agaugcucau gugcagcacc      300

cccgccaccg gguccggcag cgccaucgcc uccggcgugg cggugugcaa gguccugcac      360

cuggaggggg aggugaacaa gaucaagagc gcccuccugu ccaccaacaa ggccgugguc      420

agccugucca acggcgugag cgugcucacg uucaaggucc uggaccugaa gaacuacauc      480

gacaagcagc uccugccgau ccugaacaag caguccugca gcauccccaa ccccgagacc      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucuccgug      600

aacgccgggg ucaccacgcc cgugagcacc uacaugcuga ccaacuccga gcuccugagc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ugccccucua cggcgugauc gacacgcccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac gaaggagggg agcaacaucu gccucacccg caccgaccgg      900

ggcugguacu gcgacaacgc gggcuccgug agcuucuucc cgcaggccga gaccugcaag      960

gucugcucca accgcguguu cugcgacacg augaacagcc ugacccugcc cuccgagguc     1020

aaccucugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggggcca ucguguccug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaag gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cgucgacacg guguccgugg ggaacacccu guacuacguc     1260

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc uggcguucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggc     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccugcuc     1500

agccugaucg ccguggggcu gcuccuguac ugcaaggccc gcuga                     1545


<210>  6436
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6436
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agaugcucau gugcuccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa ccccgagacc      540

gucauggagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

gucugcucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaacaag ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1260

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuga                     1545


<210>  6437
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6437
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugaccugc agaugcuuau guguuccaca      300

cccgccaccg ggucuggauc ggcuauagca ucaggcgugg ccgucugcaa ggugcugcac      360

uuggagggug agguuaacaa aaucaagagc gcucuccuga guacgaauaa agccgugguc      420

ucccugucua acggggugag cguacucacu uuuaagguuu uagaucugaa gaauuacauu      480

gacaaacagc uuuugccuau ccugaacaag caauccuguu caauuccaaa uccggaaacc      540

gugauggagu uccagcagaa aaacaauagg cuacucgaaa ucacacggga guuuaguguc      600

aacgcgggag ugacuacccc cgugagcaca uauaugcuga ccaauucuga gcuucugucc      660

uugauaaacg auaugccuau uacgaacgac cagaagaaac ucaugucaaa uaacguccaa      720

aucguucgcc agcagagcua caguauuaug ugcaucauca aggaagaggu gcuggcauau      780

guagugcagu uaccacugua cggcgucauu gauacucccu guuggaaacu ccauacaucu      840

ccucuuugca ccacuaauac aaaggaaggc uccaacauau gucugacccg aacggaccgu      900

gggugguacu gcgauaaugc cggaagcgug ucguucuuuc cacaagcuga gaccuguaag      960

guuugcucua acagaguguu cugcgacaca augaacuccu ugacucuacc cucagaaguc     1020

aaucugugua auguggauau cuuuaacccu aaauaugacu gcaagauuau gaccaguaaa     1080

acagauguaa gcuccucugu uaucacuagc cucggugcca uagugucaug uuacggcaag     1140

accaaaugca cagcaaguaa uaagaacaag gggauuauca aaaccuucuc caauggaugu     1200

gacuauguca gcaacaaggg cguggacacu gucucugugg guaauacgcu guacuauguu     1260

aacaaacagg aggggcaguc acuuuacgug aagggagagc caaucauuaa cuuuuaugau     1320

ccgcugguau uccccaguga cgaauuugau gcuagcaucu cccaagucaa ugagaaaauu     1380

aaccagucuu uggccuucau aaggaagucg gacgaacucc ugcacaaugu gaacgcgggc     1440

aagagcacaa ccaauaucau gauuacuacc aucaucauug uuauaaucgu gauuuuacug     1500

ucccuaaucg ccgucggccu ccugcuuuac ugcaaagcac gguga                     1545


<210>  6438
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6438
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agaugcugau gugcagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa ccccgagacc      540

gugauggagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugugcagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaag ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1260

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gauga                     1545


<210>  6439
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6439
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagaa uaaaugcaac gggaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggaccucc agaugcugau guguagcacc      300

cccgccacag gauccggcuc ugcuauugcc agcggggucg cggugugcaa gguucugcac      360

cucgagggag aggugaacaa aaucaagucc gcccugcuua gcaccaauaa agcugucgug      420

ucucugucca acggcguuag cgugcucaca uuuaaggucc uggaucuuaa gaauuacauu      480

gacaaacagc ugcucccuau ccugaacaag caaucuuguu ccauuccgaa ucccgaaacc      540

gugauggagu uccagcagaa aaacaaucgg cugcucgaaa ucacgcgcga guuuagcgug      600

aacgccggcg ucacaacccc uguuucuaca uauaugcuga ccaauuccga gcuucugagc      660

cucauuaacg auaugcccau caccaacgac cagaagaaac ugauguccaa uaacgugcaa      720

aucgugagac agcagucuua cagcauuaug ugcaucauua aggaagaggu ccuugcuuau      780

gugguucagc ugccucucua cggggugauc gauacacccu guuggaaacu gcauacgucc      840

ccucugugca ccacaaauac caaggaagga agcaacauuu gucucacacg gaccgaccgc      900

ggcugguacu gcgauaaugc cgggucuguc uccuucuuuc cgcaagcgga gacguguaag      960

gugugcagca acagaguuuu cugcgacaca augaacucuc ugacccuucc cagcgaagug     1020

aaucugugua augucgauau cuuuaacccu aaauaugacu gcaagaucau gaccuccaaa     1080

acagaugugu cuagcuccgu cauuaccagc cucggagcca ucgugucuug uuacggcaag     1140

acaaaaugca cggcuuccaa uaagaacaag gggauuauca aaaccuucag caauggaugu     1200

gacuauguuu cuaacaaggg cguggacaca gucuccgugg gcaauacccu guacuauguu     1260

aacaaacagg aggggcagag ccuuuacgug aagggagagc ccauuaucaa cuuuuaugau     1320

ccucuggucu uccccuccga cgaauuugau gccucuauca gccaagugaa ugagaaaauu     1380

aaccaguccc ucgcuuucau ccggaagucu gacgaacugc ugcacaaugu gaacgccggc     1440

aagagcacaa ccaauauuau gaucacgacc auuaucauug uuaucaucgu cauucuccug     1500

ucccuuaucg ccguggggcu gcuccuguac ugcaaagcuc gcuga                     1545


<210>  6440
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6440
auggaacuac ucauauuaaa agcaaacgca auaacaacga uauuaacagc uguaacauuc       60

ugcuuugcau caggccaaaa uaucaccgaa gaauuuuauc aaagcacaug cucugcagua      120

uccaaaggau acuuaggagc auuaagaaca ggcugguaca cauccguaau aacaauagaa      180

cuaucaaaca ucaaagaaaa caaaugcaac ggcacagacg ccaaaguaaa acucauaaaa      240

caagaacuag acaaauauaa aaacgcagua acagaucuac aaaugcucau gugcuccaca      300

ccagcaaccg gaucugguuc agccauagca uccggcguag ccgucugcaa aguauuacac      360

cucgaaggag aaguaaacaa aauaaaaucu gcccuauuau cuacaaauaa agccguagua      420

agucuaagua acggaguauc aguacuaaca uuuaaagucc uagaccugaa aaacuauauc      480

gacaaacaac uauuaccaau acuaaacaaa caauccuguu ccaucccuaa cccagaaaca      540

guuauggaau uucaacaaaa aaauaaccgc cuuuuagaaa uaacuagaga auuuucagua      600

aacgcaggag uuacaacacc aguaucaaca uacaugcuaa caaauucaga auuauuaucc      660

cuuauaaaug acaugccuau cacaaacgau caaaaaaaau uaauguccaa caacguacaa      720

auaguaagac aacaaucaua uuccaucaug ugcaucauaa aagaagaagu ccucgcauac      780

guagugcaac uaccacuaua cggagucaua gauacacccu guuggaaacu ucacacaucu      840

ccacuaugca caacaaacac gaaagaagga uccaacauau gccuaacacg aacagacaga      900

ggaugguauu gcgacaacgc uggaagugug agcuucuucc cucaagcaga aacuugcaaa      960

guaugcagca aucguguauu cugcgacaca augaacucau uaacacuccc aagcgaagua     1020

aaccucugca auguagacau cuuuaaucca aaauacgauu guaaaauaau gacuucaaaa     1080

acagacgucu caucaucugu aauaacaucu uuaggagcaa uaguuucuug cuacgguaaa     1140

acaaaaugca ccgcauccaa caaaaacaaa ggaauaauaa aaacauucuc uaacggcugc     1200

gauuacguau cuaacaaagg aguugacaca gucucaguag gaaacacacu auacuacgua     1260

aacaaacaag aaggacaaag ccuauacgua aaaggagaac caauaauaaa cuucuaugac     1320

ccauuaguau uuccaagcga ugaauuugac gcuucaauau cacaagucaa ugaaaaaaua     1380

aaucagagcu uagcauucau aagaaaaucu gaugaacuac uacacaaugu aaaugcagga     1440

aaauccacua ccaacauaau gauuaccaca auuauaauag uuaucauagu aauacuauua     1500

ucacuaauag ccguuggauu acuacuauac ugcaaagcaa gauaa                     1545


<210>  6441
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut6

<400>  6441
auggaacuac ucauccuaaa agcaaacgcc aucaccacca uacuaaccgc cgucaccuuc       60

ugcuucgccu cgggacaaaa caucaccgaa gaguucuacc agucaacgug cuccgccguc      120

ucaaaaggcu accuaggcgc ccuccgcacc gggugguaua ccuccgucau aacuaucgaa      180

cucucuaaca ucaaagaaaa caaauguaac ggcaccgacg ccaaagucaa acuaaucaaa      240

caagaacugg acaaauacaa aaacgccguc accgaccuac aaaugcucau gugcuccacu      300

ccagccaccg gcuccgguag cgcaaucgcc ucaggcguag cuguaugcaa aguccuccac      360

cuagaaggcg aaguaaacaa aauaaaaucc gcccuccucu caaccaacaa ggccgucguc      420

ucacucucaa acggcgucuc cguacucacc uuuaaagucc uagaccuuaa aaacuacauc      480

gacaaacaac ugcuaccaau ccucaacaaa caaucaugca gcaucccaaa cccggaaaca      540

gucauggagu uccaacagaa aaacaaccga cuccucgaaa ucacccgcga guucuccguc      600

aacgccggag ucaccacacc uguaagcaca uacaugcuua cuaauuccga acuccuuuca      660

cuaauaaacg acaugccaau aaccaacgac caaaagaaac ucauguccaa caacguacaa      720

aucguacgcc aacaauccua cuccaucaug ugcaucauca aagaagaagu ccuggccuau      780

gucguacaac ucccccuuua cggugucauc gacacacccu gcuggaaacu acacaccagc      840

ccccucugca caacaaacac caaagaaggc uccaacaucu gccucacccg uaccgaccga      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaagccga aaccugcaaa      960

gucugcagca accgcgucuu cugcgauacc augaacuccc ucacacuccc aucugaaguc     1020

aaccucugca acgucgauau uuucaaucca aaauacgacu gcaaaaucau gacuagcaaa     1080

accgacguua gcuccuccgu caucaccucc cucggcgcca uaguuucaug cuacggcaaa     1140

accaaaugca ccgccuccaa caaaaacaaa ggcaucauaa aaaccuucuc caacgggugc     1200

gacuacguau cuaauaaagg agucgacacc gucucaguag gaaacacccu cuacuauguc     1260

aacaaacaag aaggccaauc acuauacguu aaaggcgaac caaucaucaa cuucuacgac     1320

ccacucgucu uccccagcga cgaguuugac gccucaaucu cgcaagucaa ugaaaagauu     1380

aaccaauccc uagccuucau ccgaaaaagu gacgaacucc uccacaacgu uaacgccggc     1440

aaaucuacaa ccaacaucau gaucaccacu auaaucaucg ucaucauagu cauacuucuc     1500

agccucaucg cagucggacu ccuccuuuau ugcaaggcac gauaa                     1545


<210>  6442
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6442
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6443
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6443
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6444
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6444
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6445
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6445
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6446
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6446
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6447
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6447
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6448
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6448
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauuaaaagc aaacgcaaua acaacgauau      120

uaacagcugu aacauucugc uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa      180

gcacaugcuc ugcaguaucc aaaggauacu uaggagcauu aagaacaggc ugguacacau      240

ccguaauaac aauagaacua ucaaacauca aagaaaacaa augcaacggc acagacgcca      300

aaguaaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa      360

ugcucaugug cuccacacca gcaaccggau cugguucagc cauagcaucc ggcguagccg      420

ucugcaaagu auuacaccuc gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua      480

caaauaaagc cguaguaagu cuaaguaacg gaguaucagu acuaacauuu aaaguccuag      540

accugaaaaa cuauaucgac aaacaacuau uaccaauacu aaacaaacaa uccuguucca      600

ucccuaaccc agaaacaguu auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa      660

cuagagaauu uucaguaaac gcaggaguua caacaccagu aucaacauac augcuaacaa      720

auucagaauu auuaucccuu auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauauuc caucaugugc aucauaaaag      840

aagaaguccu cgcauacgua gugcaacuac cacuauacgg agucauagau acacccuguu      900

ggaaacuuca cacaucucca cuaugcacaa caaacacgaa agaaggaucc aacauaugcc      960

uaacacgaac agacagagga ugguauugcg acaacgcugg aagugugagc uucuucccuc     1020

aagcagaaac uugcaaagua ugcagcaauc guguauucug cgacacaaug aacucauuaa     1080

cacucccaag cgaaguaaac cucugcaaug uagacaucuu uaauccaaaa uacgauugua     1140

aaauaaugac uucaaaaaca gacgucucau caucuguaau aacaucuuua ggagcaauag     1200

uuucuugcua cgguaaaaca aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa     1260

cauucucuaa cggcugcgau uacguaucua acaaaggagu ugacacaguc ucaguaggaa     1320

acacacuaua cuacguaaac aaacaagaag gacaaagccu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca uuaguauuuc caagcgauga auuugacgcu ucaauaucac     1440

aagucaauga aaaaauaaau cagagcuuag cauucauaag aaaaucugau gaacuacuac     1500

acaauguaaa ugcaggaaaa uccacuacca acauaaugau uaccacaauu auaauaguua     1560

ucauaguaau acuauuauca cuaauagccg uuggauuacu acuauacugc aaagcaagau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6449
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6449
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc aaacgccauc accaccauac      120

uaaccgccgu caccuucugc uucgccucgg gacaaaacau caccgaagag uucuaccagu      180

caacgugcuc cgccgucuca aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu      240

ccgucauaac uaucgaacuc ucuaacauca aagaaaacaa auguaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa      360

ugcucaugug cuccacucca gccaccggcu ccgguagcgc aaucgccuca ggcguagcug      420

uaugcaaagu ccuccaccua gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa      480

ccaacaaggc cgucgucuca cucucaaacg gcgucuccgu acucaccuuu aaaguccuag      540

accuuaaaaa cuacaucgac aaacaacugc uaccaauccu caacaaacaa ucaugcagca      600

ucccaaaccc ggaaacaguc auggaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gccggaguca ccacaccugu aagcacauac augcuuacua      720

auuccgaacu ccuuucacua auaaacgaca ugccaauaac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guacgccaac aauccuacuc caucaugugc aucaucaaag      840

aagaaguccu ggccuauguc guacaacucc cccuuuacgg ugucaucgac acacccugcu      900

ggaaacuaca caccagcccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccguac cgaccgaggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac cugcaaaguc ugcagcaacc gcgucuucug cgauaccaug aacucccuca     1080

cacucccauc ugaagucaac cucugcaacg ucgauauuuu caauccaaaa uacgacugca     1140

aaaucaugac uagcaaaacc gacguuagcu ccuccgucau caccucccuc ggcgccauag     1200

uuucaugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

ccuucuccaa cgggugcgac uacguaucua auaaaggagu cgacaccguc ucaguaggaa     1320

acacccucua cuaugucaac aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa     1380

ucaucaacuu cuacgaccca cucgucuucc ccagcgacga guuugacgcc ucaaucucgc     1440

aagucaauga aaagauuaac caaucccuag ccuucauccg aaaaagugac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuacaacca acaucaugau caccacuaua aucaucguca     1560

ucauagucau acuucucagc cucaucgcag ucggacuccu ccuuuauugc aaggcacgau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  6450
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6450
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6451
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6451
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6452
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6452
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6453
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6453
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6454
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6454
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6455
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6455
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6456
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6456
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auuaaaagca      120

aacgcaauaa caacgauauu aacagcugua acauucugcu uugcaucagg ccaaaauauc      180

accgaagaau uuuaucaaag cacaugcucu gcaguaucca aaggauacuu aggagcauua      240

agaacaggcu gguacacauc cguaauaaca auagaacuau caaacaucaa agaaaacaaa      300

ugcaacggca cagacgccaa aguaaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacag aucuacaaau gcucaugugc uccacaccag caaccggauc ugguucagcc      420

auagcauccg gcguagccgu cugcaaagua uuacaccucg aaggagaagu aaacaaaaua      480

aaaucugccc uauuaucuac aaauaaagcc guaguaaguc uaaguaacgg aguaucagua      540

cuaacauuua aaguccuaga ccugaaaaac uauaucgaca aacaacuauu accaauacua      600

aacaaacaau ccuguuccau cccuaaccca gaaacaguua uggaauuuca acaaaaaaau      660

aaccgccuuu uagaaauaac uagagaauuu ucaguaaacg caggaguuac aacaccagua      720

ucaacauaca ugcuaacaaa uucagaauua uuaucccuua uaaaugacau gccuaucaca      780

aacgaucaaa aaaaauuaau guccaacaac guacaaauag uaagacaaca aucauauucc      840

aucaugugca ucauaaaaga agaaguccuc gcauacguag ugcaacuacc acuauacgga      900

gucauagaua cacccuguug gaaacuucac acaucuccac uaugcacaac aaacacgaaa      960

gaaggaucca acauaugccu aacacgaaca gacagaggau gguauugcga caacgcugga     1020

agugugagcu ucuucccuca agcagaaacu ugcaaaguau gcagcaaucg uguauucugc     1080

gacacaauga acucauuaac acucccaagc gaaguaaacc ucugcaaugu agacaucuuu     1140

aauccaaaau acgauuguaa aauaaugacu ucaaaaacag acgucucauc aucuguaaua     1200

acaucuuuag gagcaauagu uucuugcuac gguaaaacaa aaugcaccgc auccaacaaa     1260

aacaaaggaa uaauaaaaac auucucuaac ggcugcgauu acguaucuaa caaaggaguu     1320

gacacagucu caguaggaaa cacacuauac uacguaaaca aacaagaagg acaaagccua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccau uaguauuucc aagcgaugaa     1440

uuugacgcuu caauaucaca agucaaugaa aaaauaaauc agagcuuagc auucauaaga     1500

aaaucugaug aacuacuaca caauguaaau gcaggaaaau ccacuaccaa cauaaugauu     1560

accacaauua uaauaguuau cauaguaaua cuauuaucac uaauagccgu uggauuacua     1620

cuauacugca aagcaagaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6457
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6457
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagca      120

aacgccauca ccaccauacu aaccgccguc accuucugcu ucgccucggg acaaaacauc      180

accgaagagu ucuaccaguc aacgugcucc gccgucucaa aaggcuaccu aggcgcccuc      240

cgcaccgggu gguauaccuc cgucauaacu aucgaacucu cuaacaucaa agaaaacaaa      300

uguaacggca ccgacgccaa agucaaacua aucaaacaag aacuggacaa auacaaaaac      360

gccgucaccg accuacaaau gcucaugugc uccacuccag ccaccggcuc cgguagcgca      420

aucgccucag gcguagcugu augcaaaguc cuccaccuag aaggcgaagu aaacaaaaua      480

aaauccgccc uccucucaac caacaaggcc gucgucucac ucucaaacgg cgucuccgua      540

cucaccuuua aaguccuaga ccuuaaaaac uacaucgaca aacaacugcu accaauccuc      600

aacaaacaau caugcagcau cccaaacccg gaaacaguca uggaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg ccggagucac cacaccugua      720

agcacauaca ugcuuacuaa uuccgaacuc cuuucacuaa uaaacgacau gccaauaacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uacgccaaca auccuacucc      840

aucaugugca ucaucaaaga agaaguccug gccuaugucg uacaacuccc ccuuuacggu      900

gucaucgaca cacccugcug gaaacuacac accagccccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccguacc gaccgaggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacc ugcaaagucu gcagcaaccg cgucuucugc     1080

gauaccauga acucccucac acucccaucu gaagucaacc ucugcaacgu cgauauuuuc     1140

aauccaaaau acgacugcaa aaucaugacu agcaaaaccg acguuagcuc cuccgucauc     1200

accucccucg gcgccauagu uucaugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac cuucuccaac gggugcgacu acguaucuaa uaaaggaguc     1320

gacaccgucu caguaggaaa cacccucuac uaugucaaca aacaagaagg ccaaucacua     1380

uacguuaaag gcgaaccaau caucaacuuc uacgacccac ucgucuuccc cagcgacgag     1440

uuugacgccu caaucucgca agucaaugaa aagauuaacc aaucccuagc cuucauccga     1500

aaaagugacg aacuccucca caacguuaac gccggcaaau cuacaaccaa caucaugauc     1560

accacuauaa ucaucgucau cauagucaua cuucucagcc ucaucgcagu cggacuccuc     1620

cuuuauugca aggcacgaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  6458
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6458
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6459
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6459
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6460
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6460
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6461
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6461
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6462
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6462
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6463
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6463
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6464
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6464
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau uaaaagcaaa cgcaauaaca acgauauuaa cagcuguaac auucugcuuu      240

gcaucaggcc aaaauaucac cgaagaauuu uaucaaagca caugcucugc aguauccaaa      300

ggauacuuag gagcauuaag aacaggcugg uacacauccg uaauaacaau agaacuauca      360

aacaucaaag aaaacaaaug caacggcaca gacgccaaag uaaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacagau cuacaaaugc ucaugugcuc cacaccagca      480

accggaucug guucagccau agcauccggc guagccgucu gcaaaguauu acaccucgaa      540

ggagaaguaa acaaaauaaa aucugcccua uuaucuacaa auaaagccgu aguaagucua      600

aguaacggag uaucaguacu aacauuuaaa guccuagacc ugaaaaacua uaucgacaaa      660

caacuauuac caauacuaaa caaacaaucc uguuccaucc cuaacccaga aacaguuaug      720

gaauuucaac aaaaaaauaa ccgccuuuua gaaauaacua gagaauuuuc aguaaacgca      780

ggaguuacaa caccaguauc aacauacaug cuaacaaauu cagaauuauu aucccuuaua      840

aaugacaugc cuaucacaaa cgaucaaaaa aaauuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauauuccau caugugcauc auaaaagaag aaguccucgc auacguagug      960

caacuaccac uauacggagu cauagauaca cccuguugga aacuucacac aucuccacua     1020

ugcacaacaa acacgaaaga aggauccaac auaugccuaa cacgaacaga cagaggaugg     1080

uauugcgaca acgcuggaag ugugagcuuc uucccucaag cagaaacuug caaaguaugc     1140

agcaaucgug uauucugcga cacaaugaac ucauuaacac ucccaagcga aguaaaccuc     1200

ugcaauguag acaucuuuaa uccaaaauac gauuguaaaa uaaugacuuc aaaaacagac     1260

gucucaucau cuguaauaac aucuuuagga gcaauaguuu cuugcuacgg uaaaacaaaa     1320

ugcaccgcau ccaacaaaaa caaaggaaua auaaaaacau ucucuaacgg cugcgauuac     1380

guaucuaaca aaggaguuga cacagucuca guaggaaaca cacuauacua cguaaacaaa     1440

caagaaggac aaagccuaua cguaaaagga gaaccaauaa uaaacuucua ugacccauua     1500

guauuuccaa gcgaugaauu ugacgcuuca auaucacaag ucaaugaaaa aauaaaucag     1560

agcuuagcau ucauaagaaa aucugaugaa cuacuacaca auguaaaugc aggaaaaucc     1620

acuaccaaca uaaugauuac cacaauuaua auaguuauca uaguaauacu auuaucacua     1680

auagccguug gauuacuacu auacugcaaa gcaagauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6465
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6465
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagcaaa cgccaucacc accauacuaa ccgccgucac cuucugcuuc      240

gccucgggac aaaacaucac cgaagaguuc uaccagucaa cgugcuccgc cgucucaaaa      300

ggcuaccuag gcgcccuccg caccgggugg uauaccuccg ucauaacuau cgaacucucu      360

aacaucaaag aaaacaaaug uaacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cuggacaaau acaaaaacgc cgucaccgac cuacaaaugc ucaugugcuc cacuccagcc      480

accggcuccg guagcgcaau cgccucaggc guagcuguau gcaaaguccu ccaccuagaa      540

ggcgaaguaa acaaaauaaa auccgcccuc cucucaacca acaaggccgu cgucucacuc      600

ucaaacggcg ucuccguacu caccuuuaaa guccuagacc uuaaaaacua caucgacaaa      660

caacugcuac caauccucaa caaacaauca ugcagcaucc caaacccgga aacagucaug      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggagucacca caccuguaag cacauacaug cuuacuaauu ccgaacuccu uucacuaaua      840

aacgacaugc caauaaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucgua      900

cgccaacaau ccuacuccau caugugcauc aucaaagaag aaguccuggc cuaugucgua      960

caacuccccc uuuacggugu caucgacaca cccugcugga aacuacacac cagcccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccguaccga ccgaggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaaccug caaagucugc     1140

agcaaccgcg ucuucugcga uaccaugaac ucccucacac ucccaucuga agucaaccuc     1200

ugcaacgucg auauuuucaa uccaaaauac gacugcaaaa ucaugacuag caaaaccgac     1260

guuagcuccu ccgucaucac cucccucggc gccauaguuu caugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaaccu ucuccaacgg gugcgacuac     1380

guaucuaaua aaggagucga caccgucuca guaggaaaca cccucuacua ugucaacaaa     1440

caagaaggcc aaucacuaua cguuaaaggc gaaccaauca ucaacuucua cgacccacuc     1500

gucuucccca gcgacgaguu ugacgccuca aucucgcaag ucaaugaaaa gauuaaccaa     1560

ucccuagccu ucauccgaaa aagugacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

acaaccaaca ucaugaucac cacuauaauc aucgucauca uagucauacu ucucagccuc     1680

aucgcagucg gacuccuccu uuauugcaag gcacgauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  6466
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6466
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6467
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6467
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6468
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6468
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6469
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6469
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6470
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6470
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6471
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6471
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6472
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6472
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu aaaagcaaac gcaauaacaa cgauauuaac agcuguaaca      180

uucugcuuug caucaggcca aaauaucacc gaagaauuuu aucaaagcac augcucugca      240

guauccaaag gauacuuagg agcauuaaga acaggcuggu acacauccgu aauaacaaua      300

gaacuaucaa acaucaaaga aaacaaaugc aacggcacag acgccaaagu aaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacagauc uacaaaugcu caugugcucc      420

acaccagcaa ccggaucugg uucagccaua gcauccggcg uagccgucug caaaguauua      480

caccucgaag gagaaguaaa caaaauaaaa ucugcccuau uaucuacaaa uaaagccgua      540

guaagucuaa guaacggagu aucaguacua acauuuaaag uccuagaccu gaaaaacuau      600

aucgacaaac aacuauuacc aauacuaaac aaacaauccu guuccauccc uaacccagaa      660

acaguuaugg aauuucaaca aaaaaauaac cgccuuuuag aaauaacuag agaauuuuca      720

guaaacgcag gaguuacaac accaguauca acauacaugc uaacaaauuc agaauuauua      780

ucccuuauaa augacaugcc uaucacaaac gaucaaaaaa aauuaauguc caacaacgua      840

caaauaguaa gacaacaauc auauuccauc augugcauca uaaaagaaga aguccucgca      900

uacguagugc aacuaccacu auacggaguc auagauacac ccuguuggaa acuucacaca      960

ucuccacuau gcacaacaaa cacgaaagaa ggauccaaca uaugccuaac acgaacagac     1020

agaggauggu auugcgacaa cgcuggaagu gugagcuucu ucccucaagc agaaacuugc     1080

aaaguaugca gcaaucgugu auucugcgac acaaugaacu cauuaacacu cccaagcgaa     1140

guaaaccucu gcaauguaga caucuuuaau ccaaaauacg auuguaaaau aaugacuuca     1200

aaaacagacg ucucaucauc uguaauaaca ucuuuaggag caauaguuuc uugcuacggu     1260

aaaacaaaau gcaccgcauc caacaaaaac aaaggaauaa uaaaaacauu cucuaacggc     1320

ugcgauuacg uaucuaacaa aggaguugac acagucucag uaggaaacac acuauacuac     1380

guaaacaaac aagaaggaca aagccuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccauuag uauuuccaag cgaugaauuu gacgcuucaa uaucacaagu caaugaaaaa     1500

auaaaucaga gcuuagcauu cauaagaaaa ucugaugaac uacuacacaa uguaaaugca     1560

ggaaaaucca cuaccaacau aaugauuacc acaauuauaa uaguuaucau aguaauacua     1620

uuaucacuaa uagccguugg auuacuacua uacugcaaag caagauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6473
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6473
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagcaaac gccaucacca ccauacuaac cgccgucacc      180

uucugcuucg ccucgggaca aaacaucacc gaagaguucu accagucaac gugcuccgcc      240

gucucaaaag gcuaccuagg cgcccuccgc accggguggu auaccuccgu cauaacuauc      300

gaacucucua acaucaaaga aaacaaaugu aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac uggacaaaua caaaaacgcc gucaccgacc uacaaaugcu caugugcucc      420

acuccagcca ccggcuccgg uagcgcaauc gccucaggcg uagcuguaug caaaguccuc      480

caccuagaag gcgaaguaaa caaaauaaaa uccgcccucc ucucaaccaa caaggccguc      540

gucucacucu caaacggcgu cuccguacuc accuuuaaag uccuagaccu uaaaaacuac      600

aucgacaaac aacugcuacc aauccucaac aaacaaucau gcagcauccc aaacccggaa      660

acagucaugg aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgccg gagucaccac accuguaagc acauacaugc uuacuaauuc cgaacuccuu      780

ucacuaauaa acgacaugcc aauaaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguac gccaacaauc cuacuccauc augugcauca ucaaagaaga aguccuggcc      900

uaugucguac aacucccccu uuacgguguc aucgacacac ccugcuggaa acuacacacc      960

agcccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccguaccgac     1020

cgaggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaaccugc     1080

aaagucugca gcaaccgcgu cuucugcgau accaugaacu cccucacacu cccaucugaa     1140

gucaaccucu gcaacgucga uauuuucaau ccaaaauacg acugcaaaau caugacuagc     1200

aaaaccgacg uuagcuccuc cgucaucacc ucccucggcg ccauaguuuc augcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaaccuu cuccaacggg     1320

ugcgacuacg uaucuaauaa aggagucgac accgucucag uaggaaacac ccucuacuau     1380

gucaacaaac aagaaggcca aucacuauac guuaaaggcg aaccaaucau caacuucuac     1440

gacccacucg ucuuccccag cgacgaguuu gacgccucaa ucucgcaagu caaugaaaag     1500

auuaaccaau cccuagccuu cauccgaaaa agugacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua caaccaacau caugaucacc acuauaauca ucgucaucau agucauacuu     1620

cucagccuca ucgcagucgg acuccuccuu uauugcaagg cacgauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  6474
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6474
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6475
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6475
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6476
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6476
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6477
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6477
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6478
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6478
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6479
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6479
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6480
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6480
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauuaaaa gcaaacgcaa uaacaacgau auuaacagcu      120

guaacauucu gcuuugcauc aggccaaaau aucaccgaag aauuuuauca aagcacaugc      180

ucugcaguau ccaaaggaua cuuaggagca uuaagaacag gcugguacac auccguaaua      240

acaauagaac uaucaaacau caaagaaaac aaaugcaacg gcacagacgc caaaguaaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguaa cagaucuaca aaugcucaug      360

ugcuccacac cagcaaccgg aucugguuca gccauagcau ccggcguagc cgucugcaaa      420

guauuacacc ucgaaggaga aguaaacaaa auaaaaucug cccuauuauc uacaaauaaa      480

gccguaguaa gucuaaguaa cggaguauca guacuaacau uuaaaguccu agaccugaaa      540

aacuauaucg acaaacaacu auuaccaaua cuaaacaaac aauccuguuc caucccuaac      600

ccagaaacag uuauggaauu ucaacaaaaa aauaaccgcc uuuuagaaau aacuagagaa      660

uuuucaguaa acgcaggagu uacaacacca guaucaacau acaugcuaac aaauucagaa      720

uuauuauccc uuauaaauga caugccuauc acaaacgauc aaaaaaaauu aauguccaac      780

aacguacaaa uaguaagaca acaaucauau uccaucaugu gcaucauaaa agaagaaguc      840

cucgcauacg uagugcaacu accacuauac ggagucauag auacacccug uuggaaacuu      900

cacacaucuc cacuaugcac aacaaacacg aaagaaggau ccaacauaug ccuaacacga      960

acagacagag gaugguauug cgacaacgcu ggaaguguga gcuucuuccc ucaagcagaa     1020

acuugcaaag uaugcagcaa ucguguauuc ugcgacacaa ugaacucauu aacacuccca     1080

agcgaaguaa accucugcaa uguagacauc uuuaauccaa aauacgauug uaaaauaaug     1140

acuucaaaaa cagacgucuc aucaucugua auaacaucuu uaggagcaau aguuucuugc     1200

uacgguaaaa caaaaugcac cgcauccaac aaaaacaaag gaauaauaaa aacauucucu     1260

aacggcugcg auuacguauc uaacaaagga guugacacag ucucaguagg aaacacacua     1320

uacuacguaa acaaacaaga aggacaaagc cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cauuaguauu uccaagcgau gaauuugacg cuucaauauc acaagucaau     1440

gaaaaaauaa aucagagcuu agcauucaua agaaaaucug augaacuacu acacaaugua     1500

aaugcaggaa aauccacuac caacauaaug auuaccacaa uuauaauagu uaucauagua     1560

auacuauuau cacuaauagc cguuggauua cuacuauacu gcaaagcaag auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6481
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6481
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gcaaacgcca ucaccaccau acuaaccgcc      120

gucaccuucu gcuucgccuc gggacaaaac aucaccgaag aguucuacca gucaacgugc      180

uccgccgucu caaaaggcua ccuaggcgcc cuccgcaccg ggugguauac cuccgucaua      240

acuaucgaac ucucuaacau caaagaaaac aaauguaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacugga caaauacaaa aacgccguca ccgaccuaca aaugcucaug      360

ugcuccacuc cagccaccgg cuccgguagc gcaaucgccu caggcguagc uguaugcaaa      420

guccuccacc uagaaggcga aguaaacaaa auaaaauccg cccuccucuc aaccaacaag      480

gccgucgucu cacucucaaa cggcgucucc guacucaccu uuaaaguccu agaccuuaaa      540

aacuacaucg acaaacaacu gcuaccaauc cucaacaaac aaucaugcag caucccaaac      600

ccggaaacag ucauggaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgccggagu caccacaccu guaagcacau acaugcuuac uaauuccgaa      720

cuccuuucac uaauaaacga caugccaaua accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguacgcca acaauccuac uccaucaugu gcaucaucaa agaagaaguc      840

cuggccuaug ucguacaacu cccccuuuac ggugucaucg acacacccug cuggaaacua      900

cacaccagcc cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgu      960

accgaccgag gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

accugcaaag ucugcagcaa ccgcgucuuc ugcgauacca ugaacucccu cacacuccca     1080

ucugaaguca accucugcaa cgucgauauu uucaauccaa aauacgacug caaaaucaug     1140

acuagcaaaa ccgacguuag cuccuccguc aucaccuccc ucggcgccau aguuucaugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aaccuucucc     1260

aacgggugcg acuacguauc uaauaaagga gucgacaccg ucucaguagg aaacacccuc     1320

uacuauguca acaaacaaga aggccaauca cuauacguua aaggcgaacc aaucaucaac     1380

uucuacgacc cacucgucuu ccccagcgac gaguuugacg ccucaaucuc gcaagucaau     1440

gaaaagauua accaaucccu agccuucauc cgaaaaagug acgaacuccu ccacaacguu     1500

aacgccggca aaucuacaac caacaucaug aucaccacua uaaucaucgu caucauaguc     1560

auacuucuca gccucaucgc agucggacuc cuccuuuauu gcaaggcacg auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  6482
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6482
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6483
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6483
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      540

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      600

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      660

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      720

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      840

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc     1140

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1200

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1260

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1500

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1740

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6484
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6484
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      780

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1500

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6485
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6485
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      540

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      600

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      660

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      720

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      780

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      840

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      900

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      960

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua     1020

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu     1080

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg     1140

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1200

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1260

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1320

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1380

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1440

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1500

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1560

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1620

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1680

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1740

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6486
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6486
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      780

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1500

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6487
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6487
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      540

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      600

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      660

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      720

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      780

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      840

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      900

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      960

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug     1020

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu     1080

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc     1140

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1200

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1260

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1320

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1380

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1440

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1500

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1560

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1620

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1680

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1740

cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6488
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6488
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuca uauuaaaagc aaacgcaaua acaacgauau uaacagcugu aacauucugc      300

uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa gcacaugcuc ugcaguaucc      360

aaaggauacu uaggagcauu aagaacaggc ugguacacau ccguaauaac aauagaacua      420

ucaaacauca aagaaaacaa augcaacggc acagacgcca aaguaaaacu cauaaaacaa      480

gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa ugcucaugug cuccacacca      540

gcaaccggau cugguucagc cauagcaucc ggcguagccg ucugcaaagu auuacaccuc      600

gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua caaauaaagc cguaguaagu      660

cuaaguaacg gaguaucagu acuaacauuu aaaguccuag accugaaaaa cuauaucgac      720

aaacaacuau uaccaauacu aaacaaacaa uccuguucca ucccuaaccc agaaacaguu      780

auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa cuagagaauu uucaguaaac      840

gcaggaguua caacaccagu aucaacauac augcuaacaa auucagaauu auuaucccuu      900

auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa uguccaacaa cguacaaaua      960

guaagacaac aaucauauuc caucaugugc aucauaaaag aagaaguccu cgcauacgua     1020

gugcaacuac cacuauacgg agucauagau acacccuguu ggaaacuuca cacaucucca     1080

cuaugcacaa caaacacgaa agaaggaucc aacauaugcc uaacacgaac agacagagga     1140

ugguauugcg acaacgcugg aagugugagc uucuucccuc aagcagaaac uugcaaagua     1200

ugcagcaauc guguauucug cgacacaaug aacucauuaa cacucccaag cgaaguaaac     1260

cucugcaaug uagacaucuu uaauccaaaa uacgauugua aaauaaugac uucaaaaaca     1320

gacgucucau caucuguaau aacaucuuua ggagcaauag uuucuugcua cgguaaaaca     1380

aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa cauucucuaa cggcugcgau     1440

uacguaucua acaaaggagu ugacacaguc ucaguaggaa acacacuaua cuacguaaac     1500

aaacaagaag gacaaagccu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1560

uuaguauuuc caagcgauga auuugacgcu ucaauaucac aagucaauga aaaaauaaau     1620

cagagcuuag cauucauaag aaaaucugau gaacuacuac acaauguaaa ugcaggaaaa     1680

uccacuacca acauaaugau uaccacaauu auaauaguua ucauaguaau acuauuauca     1740

cuaauagccg uuggauuacu acuauacugc aaagcaagau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6489
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6489
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuca uccuaaaagc aaacgccauc accaccauac uaaccgccgu caccuucugc      300

uucgccucgg gacaaaacau caccgaagag uucuaccagu caacgugcuc cgccgucuca      360

aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu ccgucauaac uaucgaacuc      420

ucuaacauca aagaaaacaa auguaacggc accgacgcca aagucaaacu aaucaaacaa      480

gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa ugcucaugug cuccacucca      540

gccaccggcu ccgguagcgc aaucgccuca ggcguagcug uaugcaaagu ccuccaccua      600

gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa ccaacaaggc cgucgucuca      660

cucucaaacg gcgucuccgu acucaccuuu aaaguccuag accuuaaaaa cuacaucgac      720

aaacaacugc uaccaauccu caacaaacaa ucaugcagca ucccaaaccc ggaaacaguc      780

auggaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      840

gccggaguca ccacaccugu aagcacauac augcuuacua auuccgaacu ccuuucacua      900

auaaacgaca ugccaauaac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      960

guacgccaac aauccuacuc caucaugugc aucaucaaag aagaaguccu ggccuauguc     1020

guacaacucc cccuuuacgg ugucaucgac acacccugcu ggaaacuaca caccagcccc     1080

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccguac cgaccgaggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac cugcaaaguc     1200

ugcagcaacc gcgucuucug cgauaccaug aacucccuca cacucccauc ugaagucaac     1260

cucugcaacg ucgauauuuu caauccaaaa uacgacugca aaaucaugac uagcaaaacc     1320

gacguuagcu ccuccgucau caccucccuc ggcgccauag uuucaugcua cggcaaaacc     1380

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa ccuucuccaa cgggugcgac     1440

uacguaucua auaaaggagu cgacaccguc ucaguaggaa acacccucua cuaugucaac     1500

aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa ucaucaacuu cuacgaccca     1560

cucgucuucc ccagcgacga guuugacgcc ucaaucucgc aagucaauga aaagauuaac     1620

caaucccuag ccuucauccg aaaaagugac gaacuccucc acaacguuaa cgccggcaaa     1680

ucuacaacca acaucaugau caccacuaua aucaucguca ucauagucau acuucucagc     1740

cucaucgcag ucggacuccu ccuuuauugc aaggcacgau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6490
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6490
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6491
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6491
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      480

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc      960

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6492
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6492
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6493
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6493
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      360

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      420

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      480

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      540

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      660

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      720

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      780

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua      840

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu      900

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg      960

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1020

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1080

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1200

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1260

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1320

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1380

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1440

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1500

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1560

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6494
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6494
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6495
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6495
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      360

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      420

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      480

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      540

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      660

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      720

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug      840

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu      900

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc      960

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1020

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1080

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1200

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1260

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1380

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1440

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1500

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1560

cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6496
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6496
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuca uauuaaaagc aaacgcaaua acaacgauau uaacagcugu aacauucugc      120

uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa gcacaugcuc ugcaguaucc      180

aaaggauacu uaggagcauu aagaacaggc ugguacacau ccguaauaac aauagaacua      240

ucaaacauca aagaaaacaa augcaacggc acagacgcca aaguaaaacu cauaaaacaa      300

gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa ugcucaugug cuccacacca      360

gcaaccggau cugguucagc cauagcaucc ggcguagccg ucugcaaagu auuacaccuc      420

gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua caaauaaagc cguaguaagu      480

cuaaguaacg gaguaucagu acuaacauuu aaaguccuag accugaaaaa cuauaucgac      540

aaacaacuau uaccaauacu aaacaaacaa uccuguucca ucccuaaccc agaaacaguu      600

auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa cuagagaauu uucaguaaac      660

gcaggaguua caacaccagu aucaacauac augcuaacaa auucagaauu auuaucccuu      720

auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa uguccaacaa cguacaaaua      780

guaagacaac aaucauauuc caucaugugc aucauaaaag aagaaguccu cgcauacgua      840

gugcaacuac cacuauacgg agucauagau acacccuguu ggaaacuuca cacaucucca      900

cuaugcacaa caaacacgaa agaaggaucc aacauaugcc uaacacgaac agacagagga      960

ugguauugcg acaacgcugg aagugugagc uucuucccuc aagcagaaac uugcaaagua     1020

ugcagcaauc guguauucug cgacacaaug aacucauuaa cacucccaag cgaaguaaac     1080

cucugcaaug uagacaucuu uaauccaaaa uacgauugua aaauaaugac uucaaaaaca     1140

gacgucucau caucuguaau aacaucuuua ggagcaauag uuucuugcua cgguaaaaca     1200

aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa cauucucuaa cggcugcgau     1260

uacguaucua acaaaggagu ugacacaguc ucaguaggaa acacacuaua cuacguaaac     1320

aaacaagaag gacaaagccu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1380

uuaguauuuc caagcgauga auuugacgcu ucaauaucac aagucaauga aaaaauaaau     1440

cagagcuuag cauucauaag aaaaucugau gaacuacuac acaauguaaa ugcaggaaaa     1500

uccacuacca acauaaugau uaccacaauu auaauaguua ucauaguaau acuauuauca     1560

cuaauagccg uuggauuacu acuauacugc aaagcaagau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6497
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6497
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuca uccuaaaagc aaacgccauc accaccauac uaaccgccgu caccuucugc      120

uucgccucgg gacaaaacau caccgaagag uucuaccagu caacgugcuc cgccgucuca      180

aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu ccgucauaac uaucgaacuc      240

ucuaacauca aagaaaacaa auguaacggc accgacgcca aagucaaacu aaucaaacaa      300

gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa ugcucaugug cuccacucca      360

gccaccggcu ccgguagcgc aaucgccuca ggcguagcug uaugcaaagu ccuccaccua      420

gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa ccaacaaggc cgucgucuca      480

cucucaaacg gcgucuccgu acucaccuuu aaaguccuag accuuaaaaa cuacaucgac      540

aaacaacugc uaccaauccu caacaaacaa ucaugcagca ucccaaaccc ggaaacaguc      600

auggaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      660

gccggaguca ccacaccugu aagcacauac augcuuacua auuccgaacu ccuuucacua      720

auaaacgaca ugccaauaac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      780

guacgccaac aauccuacuc caucaugugc aucaucaaag aagaaguccu ggccuauguc      840

guacaacucc cccuuuacgg ugucaucgac acacccugcu ggaaacuaca caccagcccc      900

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccguac cgaccgaggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac cugcaaaguc     1020

ugcagcaacc gcgucuucug cgauaccaug aacucccuca cacucccauc ugaagucaac     1080

cucugcaacg ucgauauuuu caauccaaaa uacgacugca aaaucaugac uagcaaaacc     1140

gacguuagcu ccuccgucau caccucccuc ggcgccauag uuucaugcua cggcaaaacc     1200

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa ccuucuccaa cgggugcgac     1260

uacguaucua auaaaggagu cgacaccguc ucaguaggaa acacccucua cuaugucaac     1320

aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa ucaucaacuu cuacgaccca     1380

cucgucuucc ccagcgacga guuugacgcc ucaaucucgc aagucaauga aaagauuaac     1440

caaucccuag ccuucauccg aaaaagugac gaacuccucc acaacguuaa cgccggcaaa     1500

ucuacaacca acaucaugau caccacuaua aucaucguca ucauagucau acuucucagc     1560

cucaucgcag ucggacuccu ccuuuauugc aaggcacgau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  6498
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6498
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6499
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6499
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6500
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6500
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6501
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6501
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6502
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6502
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6503
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6503
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6504
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6504
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauuaaaagc aaacgcaaua acaacgauau      120

uaacagcugu aacauucugc uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa      180

gcacaugcuc ugcaguaucc aaaggauacu uaggagcauu aagaacaggc ugguacacau      240

ccguaauaac aauagaacua ucaaacauca aagaaaacaa augcaacggc acagacgcca      300

aaguaaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa      360

ugcucaugug cuccacacca gcaaccggau cugguucagc cauagcaucc ggcguagccg      420

ucugcaaagu auuacaccuc gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua      480

caaauaaagc cguaguaagu cuaaguaacg gaguaucagu acuaacauuu aaaguccuag      540

accugaaaaa cuauaucgac aaacaacuau uaccaauacu aaacaaacaa uccuguucca      600

ucccuaaccc agaaacaguu auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa      660

cuagagaauu uucaguaaac gcaggaguua caacaccagu aucaacauac augcuaacaa      720

auucagaauu auuaucccuu auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauauuc caucaugugc aucauaaaag      840

aagaaguccu cgcauacgua gugcaacuac cacuauacgg agucauagau acacccuguu      900

ggaaacuuca cacaucucca cuaugcacaa caaacacgaa agaaggaucc aacauaugcc      960

uaacacgaac agacagagga ugguauugcg acaacgcugg aagugugagc uucuucccuc     1020

aagcagaaac uugcaaagua ugcagcaauc guguauucug cgacacaaug aacucauuaa     1080

cacucccaag cgaaguaaac cucugcaaug uagacaucuu uaauccaaaa uacgauugua     1140

aaauaaugac uucaaaaaca gacgucucau caucuguaau aacaucuuua ggagcaauag     1200

uuucuugcua cgguaaaaca aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa     1260

cauucucuaa cggcugcgau uacguaucua acaaaggagu ugacacaguc ucaguaggaa     1320

acacacuaua cuacguaaac aaacaagaag gacaaagccu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca uuaguauuuc caagcgauga auuugacgcu ucaauaucac     1440

aagucaauga aaaaauaaau cagagcuuag cauucauaag aaaaucugau gaacuacuac     1500

acaauguaaa ugcaggaaaa uccacuacca acauaaugau uaccacaauu auaauaguua     1560

ucauaguaau acuauuauca cuaauagccg uuggauuacu acuauacugc aaagcaagau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6505
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6505
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc aaacgccauc accaccauac      120

uaaccgccgu caccuucugc uucgccucgg gacaaaacau caccgaagag uucuaccagu      180

caacgugcuc cgccgucuca aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu      240

ccgucauaac uaucgaacuc ucuaacauca aagaaaacaa auguaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa      360

ugcucaugug cuccacucca gccaccggcu ccgguagcgc aaucgccuca ggcguagcug      420

uaugcaaagu ccuccaccua gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa      480

ccaacaaggc cgucgucuca cucucaaacg gcgucuccgu acucaccuuu aaaguccuag      540

accuuaaaaa cuacaucgac aaacaacugc uaccaauccu caacaaacaa ucaugcagca      600

ucccaaaccc ggaaacaguc auggaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gccggaguca ccacaccugu aagcacauac augcuuacua      720

auuccgaacu ccuuucacua auaaacgaca ugccaauaac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guacgccaac aauccuacuc caucaugugc aucaucaaag      840

aagaaguccu ggccuauguc guacaacucc cccuuuacgg ugucaucgac acacccugcu      900

ggaaacuaca caccagcccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccguac cgaccgaggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac cugcaaaguc ugcagcaacc gcgucuucug cgauaccaug aacucccuca     1080

cacucccauc ugaagucaac cucugcaacg ucgauauuuu caauccaaaa uacgacugca     1140

aaaucaugac uagcaaaacc gacguuagcu ccuccgucau caccucccuc ggcgccauag     1200

uuucaugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

ccuucuccaa cgggugcgac uacguaucua auaaaggagu cgacaccguc ucaguaggaa     1320

acacccucua cuaugucaac aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa     1380

ucaucaacuu cuacgaccca cucgucuucc ccagcgacga guuugacgcc ucaaucucgc     1440

aagucaauga aaagauuaac caaucccuag ccuucauccg aaaaagugac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuacaacca acaucaugau caccacuaua aucaucguca     1560

ucauagucau acuucucagc cucaucgcag ucggacuccu ccuuuauugc aaggcacgau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6506
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6506
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6507
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6507
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6508
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6508
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6509
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6509
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6510
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6510
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6511
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6511
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6512
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6512
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauuaaaagc aaacgcaaua acaacgauau      120

uaacagcugu aacauucugc uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa      180

gcacaugcuc ugcaguaucc aaaggauacu uaggagcauu aagaacaggc ugguacacau      240

ccguaauaac aauagaacua ucaaacauca aagaaaacaa augcaacggc acagacgcca      300

aaguaaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa      360

ugcucaugug cuccacacca gcaaccggau cugguucagc cauagcaucc ggcguagccg      420

ucugcaaagu auuacaccuc gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua      480

caaauaaagc cguaguaagu cuaaguaacg gaguaucagu acuaacauuu aaaguccuag      540

accugaaaaa cuauaucgac aaacaacuau uaccaauacu aaacaaacaa uccuguucca      600

ucccuaaccc agaaacaguu auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa      660

cuagagaauu uucaguaaac gcaggaguua caacaccagu aucaacauac augcuaacaa      720

auucagaauu auuaucccuu auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauauuc caucaugugc aucauaaaag      840

aagaaguccu cgcauacgua gugcaacuac cacuauacgg agucauagau acacccuguu      900

ggaaacuuca cacaucucca cuaugcacaa caaacacgaa agaaggaucc aacauaugcc      960

uaacacgaac agacagagga ugguauugcg acaacgcugg aagugugagc uucuucccuc     1020

aagcagaaac uugcaaagua ugcagcaauc guguauucug cgacacaaug aacucauuaa     1080

cacucccaag cgaaguaaac cucugcaaug uagacaucuu uaauccaaaa uacgauugua     1140

aaauaaugac uucaaaaaca gacgucucau caucuguaau aacaucuuua ggagcaauag     1200

uuucuugcua cgguaaaaca aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa     1260

cauucucuaa cggcugcgau uacguaucua acaaaggagu ugacacaguc ucaguaggaa     1320

acacacuaua cuacguaaac aaacaagaag gacaaagccu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca uuaguauuuc caagcgauga auuugacgcu ucaauaucac     1440

aagucaauga aaaaauaaau cagagcuuag cauucauaag aaaaucugau gaacuacuac     1500

acaauguaaa ugcaggaaaa uccacuacca acauaaugau uaccacaauu auaauaguua     1560

ucauaguaau acuauuauca cuaauagccg uuggauuacu acuauacugc aaagcaagau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6513
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6513
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc aaacgccauc accaccauac      120

uaaccgccgu caccuucugc uucgccucgg gacaaaacau caccgaagag uucuaccagu      180

caacgugcuc cgccgucuca aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu      240

ccgucauaac uaucgaacuc ucuaacauca aagaaaacaa auguaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa      360

ugcucaugug cuccacucca gccaccggcu ccgguagcgc aaucgccuca ggcguagcug      420

uaugcaaagu ccuccaccua gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa      480

ccaacaaggc cgucgucuca cucucaaacg gcgucuccgu acucaccuuu aaaguccuag      540

accuuaaaaa cuacaucgac aaacaacugc uaccaauccu caacaaacaa ucaugcagca      600

ucccaaaccc ggaaacaguc auggaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gccggaguca ccacaccugu aagcacauac augcuuacua      720

auuccgaacu ccuuucacua auaaacgaca ugccaauaac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guacgccaac aauccuacuc caucaugugc aucaucaaag      840

aagaaguccu ggccuauguc guacaacucc cccuuuacgg ugucaucgac acacccugcu      900

ggaaacuaca caccagcccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccguac cgaccgaggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac cugcaaaguc ugcagcaacc gcgucuucug cgauaccaug aacucccuca     1080

cacucccauc ugaagucaac cucugcaacg ucgauauuuu caauccaaaa uacgacugca     1140

aaaucaugac uagcaaaacc gacguuagcu ccuccgucau caccucccuc ggcgccauag     1200

uuucaugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

ccuucuccaa cgggugcgac uacguaucua auaaaggagu cgacaccguc ucaguaggaa     1320

acacccucua cuaugucaac aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa     1380

ucaucaacuu cuacgaccca cucgucuucc ccagcgacga guuugacgcc ucaaucucgc     1440

aagucaauga aaagauuaac caaucccuag ccuucauccg aaaaagugac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuacaacca acaucaugau caccacuaua aucaucguca     1560

ucauagucau acuucucagc cucaucgcag ucggacuccu ccuuuauugc aaggcacgau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  6514
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6514
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6515
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6515
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6516
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6516
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6517
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6517
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6518
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6518
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6519
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6519
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6520
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6520
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu aaaagcaaac gcaauaacaa cgauauuaac agcuguaaca      180

uucugcuuug caucaggcca aaauaucacc gaagaauuuu aucaaagcac augcucugca      240

guauccaaag gauacuuagg agcauuaaga acaggcuggu acacauccgu aauaacaaua      300

gaacuaucaa acaucaaaga aaacaaaugc aacggcacag acgccaaagu aaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacagauc uacaaaugcu caugugcucc      420

acaccagcaa ccggaucugg uucagccaua gcauccggcg uagccgucug caaaguauua      480

caccucgaag gagaaguaaa caaaauaaaa ucugcccuau uaucuacaaa uaaagccgua      540

guaagucuaa guaacggagu aucaguacua acauuuaaag uccuagaccu gaaaaacuau      600

aucgacaaac aacuauuacc aauacuaaac aaacaauccu guuccauccc uaacccagaa      660

acaguuaugg aauuucaaca aaaaaauaac cgccuuuuag aaauaacuag agaauuuuca      720

guaaacgcag gaguuacaac accaguauca acauacaugc uaacaaauuc agaauuauua      780

ucccuuauaa augacaugcc uaucacaaac gaucaaaaaa aauuaauguc caacaacgua      840

caaauaguaa gacaacaauc auauuccauc augugcauca uaaaagaaga aguccucgca      900

uacguagugc aacuaccacu auacggaguc auagauacac ccuguuggaa acuucacaca      960

ucuccacuau gcacaacaaa cacgaaagaa ggauccaaca uaugccuaac acgaacagac     1020

agaggauggu auugcgacaa cgcuggaagu gugagcuucu ucccucaagc agaaacuugc     1080

aaaguaugca gcaaucgugu auucugcgac acaaugaacu cauuaacacu cccaagcgaa     1140

guaaaccucu gcaauguaga caucuuuaau ccaaaauacg auuguaaaau aaugacuuca     1200

aaaacagacg ucucaucauc uguaauaaca ucuuuaggag caauaguuuc uugcuacggu     1260

aaaacaaaau gcaccgcauc caacaaaaac aaaggaauaa uaaaaacauu cucuaacggc     1320

ugcgauuacg uaucuaacaa aggaguugac acagucucag uaggaaacac acuauacuac     1380

guaaacaaac aagaaggaca aagccuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccauuag uauuuccaag cgaugaauuu gacgcuucaa uaucacaagu caaugaaaaa     1500

auaaaucaga gcuuagcauu cauaagaaaa ucugaugaac uacuacacaa uguaaaugca     1560

ggaaaaucca cuaccaacau aaugauuacc acaauuauaa uaguuaucau aguaauacua     1620

uuaucacuaa uagccguugg auuacuacua uacugcaaag caagauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6521
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6521
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagcaaac gccaucacca ccauacuaac cgccgucacc      180

uucugcuucg ccucgggaca aaacaucacc gaagaguucu accagucaac gugcuccgcc      240

gucucaaaag gcuaccuagg cgcccuccgc accggguggu auaccuccgu cauaacuauc      300

gaacucucua acaucaaaga aaacaaaugu aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac uggacaaaua caaaaacgcc gucaccgacc uacaaaugcu caugugcucc      420

acuccagcca ccggcuccgg uagcgcaauc gccucaggcg uagcuguaug caaaguccuc      480

caccuagaag gcgaaguaaa caaaauaaaa uccgcccucc ucucaaccaa caaggccguc      540

gucucacucu caaacggcgu cuccguacuc accuuuaaag uccuagaccu uaaaaacuac      600

aucgacaaac aacugcuacc aauccucaac aaacaaucau gcagcauccc aaacccggaa      660

acagucaugg aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgccg gagucaccac accuguaagc acauacaugc uuacuaauuc cgaacuccuu      780

ucacuaauaa acgacaugcc aauaaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguac gccaacaauc cuacuccauc augugcauca ucaaagaaga aguccuggcc      900

uaugucguac aacucccccu uuacgguguc aucgacacac ccugcuggaa acuacacacc      960

agcccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccguaccgac     1020

cgaggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaaccugc     1080

aaagucugca gcaaccgcgu cuucugcgau accaugaacu cccucacacu cccaucugaa     1140

gucaaccucu gcaacgucga uauuuucaau ccaaaauacg acugcaaaau caugacuagc     1200

aaaaccgacg uuagcuccuc cgucaucacc ucccucggcg ccauaguuuc augcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaaccuu cuccaacggg     1320

ugcgacuacg uaucuaauaa aggagucgac accgucucag uaggaaacac ccucuacuau     1380

gucaacaaac aagaaggcca aucacuauac guuaaaggcg aaccaaucau caacuucuac     1440

gacccacucg ucuuccccag cgacgaguuu gacgccucaa ucucgcaagu caaugaaaag     1500

auuaaccaau cccuagccuu cauccgaaaa agugacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua caaccaacau caugaucacc acuauaauca ucgucaucau agucauacuu     1620

cucagccuca ucgcagucgg acuccuccuu uauugcaagg cacgauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  6522
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6522
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6523
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6523
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6524
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6524
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6525
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6525
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6526
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6526
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6527
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6527
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6528
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6528
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auuaaaagca      120

aacgcaauaa caacgauauu aacagcugua acauucugcu uugcaucagg ccaaaauauc      180

accgaagaau uuuaucaaag cacaugcucu gcaguaucca aaggauacuu aggagcauua      240

agaacaggcu gguacacauc cguaauaaca auagaacuau caaacaucaa agaaaacaaa      300

ugcaacggca cagacgccaa aguaaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacag aucuacaaau gcucaugugc uccacaccag caaccggauc ugguucagcc      420

auagcauccg gcguagccgu cugcaaagua uuacaccucg aaggagaagu aaacaaaaua      480

aaaucugccc uauuaucuac aaauaaagcc guaguaaguc uaaguaacgg aguaucagua      540

cuaacauuua aaguccuaga ccugaaaaac uauaucgaca aacaacuauu accaauacua      600

aacaaacaau ccuguuccau cccuaaccca gaaacaguua uggaauuuca acaaaaaaau      660

aaccgccuuu uagaaauaac uagagaauuu ucaguaaacg caggaguuac aacaccagua      720

ucaacauaca ugcuaacaaa uucagaauua uuaucccuua uaaaugacau gccuaucaca      780

aacgaucaaa aaaaauuaau guccaacaac guacaaauag uaagacaaca aucauauucc      840

aucaugugca ucauaaaaga agaaguccuc gcauacguag ugcaacuacc acuauacgga      900

gucauagaua cacccuguug gaaacuucac acaucuccac uaugcacaac aaacacgaaa      960

gaaggaucca acauaugccu aacacgaaca gacagaggau gguauugcga caacgcugga     1020

agugugagcu ucuucccuca agcagaaacu ugcaaaguau gcagcaaucg uguauucugc     1080

gacacaauga acucauuaac acucccaagc gaaguaaacc ucugcaaugu agacaucuuu     1140

aauccaaaau acgauuguaa aauaaugacu ucaaaaacag acgucucauc aucuguaaua     1200

acaucuuuag gagcaauagu uucuugcuac gguaaaacaa aaugcaccgc auccaacaaa     1260

aacaaaggaa uaauaaaaac auucucuaac ggcugcgauu acguaucuaa caaaggaguu     1320

gacacagucu caguaggaaa cacacuauac uacguaaaca aacaagaagg acaaagccua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccau uaguauuucc aagcgaugaa     1440

uuugacgcuu caauaucaca agucaaugaa aaaauaaauc agagcuuagc auucauaaga     1500

aaaucugaug aacuacuaca caauguaaau gcaggaaaau ccacuaccaa cauaaugauu     1560

accacaauua uaauaguuau cauaguaaua cuauuaucac uaauagccgu uggauuacua     1620

cuauacugca aagcaagaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6529
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6529
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagca      120

aacgccauca ccaccauacu aaccgccguc accuucugcu ucgccucggg acaaaacauc      180

accgaagagu ucuaccaguc aacgugcucc gccgucucaa aaggcuaccu aggcgcccuc      240

cgcaccgggu gguauaccuc cgucauaacu aucgaacucu cuaacaucaa agaaaacaaa      300

uguaacggca ccgacgccaa agucaaacua aucaaacaag aacuggacaa auacaaaaac      360

gccgucaccg accuacaaau gcucaugugc uccacuccag ccaccggcuc cgguagcgca      420

aucgccucag gcguagcugu augcaaaguc cuccaccuag aaggcgaagu aaacaaaaua      480

aaauccgccc uccucucaac caacaaggcc gucgucucac ucucaaacgg cgucuccgua      540

cucaccuuua aaguccuaga ccuuaaaaac uacaucgaca aacaacugcu accaauccuc      600

aacaaacaau caugcagcau cccaaacccg gaaacaguca uggaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg ccggagucac cacaccugua      720

agcacauaca ugcuuacuaa uuccgaacuc cuuucacuaa uaaacgacau gccaauaacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uacgccaaca auccuacucc      840

aucaugugca ucaucaaaga agaaguccug gccuaugucg uacaacuccc ccuuuacggu      900

gucaucgaca cacccugcug gaaacuacac accagccccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccguacc gaccgaggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacc ugcaaagucu gcagcaaccg cgucuucugc     1080

gauaccauga acucccucac acucccaucu gaagucaacc ucugcaacgu cgauauuuuc     1140

aauccaaaau acgacugcaa aaucaugacu agcaaaaccg acguuagcuc cuccgucauc     1200

accucccucg gcgccauagu uucaugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac cuucuccaac gggugcgacu acguaucuaa uaaaggaguc     1320

gacaccgucu caguaggaaa cacccucuac uaugucaaca aacaagaagg ccaaucacua     1380

uacguuaaag gcgaaccaau caucaacuuc uacgacccac ucgucuuccc cagcgacgag     1440

uuugacgccu caaucucgca agucaaugaa aagauuaacc aaucccuagc cuucauccga     1500

aaaagugacg aacuccucca caacguuaac gccggcaaau cuacaaccaa caucaugauc     1560

accacuauaa ucaucgucau cauagucaua cuucucagcc ucaucgcagu cggacuccuc     1620

cuuuauugca aggcacgaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  6530
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6530
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6531
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6531
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6532
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6532
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6533
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6533
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6534
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6534
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6535
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6535
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6536
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6536
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu aaaagcaaac gcaauaacaa cgauauuaac agcuguaaca      180

uucugcuuug caucaggcca aaauaucacc gaagaauuuu aucaaagcac augcucugca      240

guauccaaag gauacuuagg agcauuaaga acaggcuggu acacauccgu aauaacaaua      300

gaacuaucaa acaucaaaga aaacaaaugc aacggcacag acgccaaagu aaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacagauc uacaaaugcu caugugcucc      420

acaccagcaa ccggaucugg uucagccaua gcauccggcg uagccgucug caaaguauua      480

caccucgaag gagaaguaaa caaaauaaaa ucugcccuau uaucuacaaa uaaagccgua      540

guaagucuaa guaacggagu aucaguacua acauuuaaag uccuagaccu gaaaaacuau      600

aucgacaaac aacuauuacc aauacuaaac aaacaauccu guuccauccc uaacccagaa      660

acaguuaugg aauuucaaca aaaaaauaac cgccuuuuag aaauaacuag agaauuuuca      720

guaaacgcag gaguuacaac accaguauca acauacaugc uaacaaauuc agaauuauua      780

ucccuuauaa augacaugcc uaucacaaac gaucaaaaaa aauuaauguc caacaacgua      840

caaauaguaa gacaacaauc auauuccauc augugcauca uaaaagaaga aguccucgca      900

uacguagugc aacuaccacu auacggaguc auagauacac ccuguuggaa acuucacaca      960

ucuccacuau gcacaacaaa cacgaaagaa ggauccaaca uaugccuaac acgaacagac     1020

agaggauggu auugcgacaa cgcuggaagu gugagcuucu ucccucaagc agaaacuugc     1080

aaaguaugca gcaaucgugu auucugcgac acaaugaacu cauuaacacu cccaagcgaa     1140

guaaaccucu gcaauguaga caucuuuaau ccaaaauacg auuguaaaau aaugacuuca     1200

aaaacagacg ucucaucauc uguaauaaca ucuuuaggag caauaguuuc uugcuacggu     1260

aaaacaaaau gcaccgcauc caacaaaaac aaaggaauaa uaaaaacauu cucuaacggc     1320

ugcgauuacg uaucuaacaa aggaguugac acagucucag uaggaaacac acuauacuac     1380

guaaacaaac aagaaggaca aagccuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccauuag uauuuccaag cgaugaauuu gacgcuucaa uaucacaagu caaugaaaaa     1500

auaaaucaga gcuuagcauu cauaagaaaa ucugaugaac uacuacacaa uguaaaugca     1560

ggaaaaucca cuaccaacau aaugauuacc acaauuauaa uaguuaucau aguaauacua     1620

uuaucacuaa uagccguugg auuacuacua uacugcaaag caagauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6537
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6537
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagcaaac gccaucacca ccauacuaac cgccgucacc      180

uucugcuucg ccucgggaca aaacaucacc gaagaguucu accagucaac gugcuccgcc      240

gucucaaaag gcuaccuagg cgcccuccgc accggguggu auaccuccgu cauaacuauc      300

gaacucucua acaucaaaga aaacaaaugu aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac uggacaaaua caaaaacgcc gucaccgacc uacaaaugcu caugugcucc      420

acuccagcca ccggcuccgg uagcgcaauc gccucaggcg uagcuguaug caaaguccuc      480

caccuagaag gcgaaguaaa caaaauaaaa uccgcccucc ucucaaccaa caaggccguc      540

gucucacucu caaacggcgu cuccguacuc accuuuaaag uccuagaccu uaaaaacuac      600

aucgacaaac aacugcuacc aauccucaac aaacaaucau gcagcauccc aaacccggaa      660

acagucaugg aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgccg gagucaccac accuguaagc acauacaugc uuacuaauuc cgaacuccuu      780

ucacuaauaa acgacaugcc aauaaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguac gccaacaauc cuacuccauc augugcauca ucaaagaaga aguccuggcc      900

uaugucguac aacucccccu uuacgguguc aucgacacac ccugcuggaa acuacacacc      960

agcccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccguaccgac     1020

cgaggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaaccugc     1080

aaagucugca gcaaccgcgu cuucugcgau accaugaacu cccucacacu cccaucugaa     1140

gucaaccucu gcaacgucga uauuuucaau ccaaaauacg acugcaaaau caugacuagc     1200

aaaaccgacg uuagcuccuc cgucaucacc ucccucggcg ccauaguuuc augcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaaccuu cuccaacggg     1320

ugcgacuacg uaucuaauaa aggagucgac accgucucag uaggaaacac ccucuacuau     1380

gucaacaaac aagaaggcca aucacuauac guuaaaggcg aaccaaucau caacuucuac     1440

gacccacucg ucuuccccag cgacgaguuu gacgccucaa ucucgcaagu caaugaaaag     1500

auuaaccaau cccuagccuu cauccgaaaa agugacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua caaccaacau caugaucacc acuauaauca ucgucaucau agucauacuu     1620

cucagccuca ucgcagucgg acuccuccuu uauugcaagg cacgauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6538
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6538
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6539
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6539
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6540
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6540
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6541
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6541
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6542
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6542
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6543
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6543
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6544
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6544
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auuaaaagca      120

aacgcaauaa caacgauauu aacagcugua acauucugcu uugcaucagg ccaaaauauc      180

accgaagaau uuuaucaaag cacaugcucu gcaguaucca aaggauacuu aggagcauua      240

agaacaggcu gguacacauc cguaauaaca auagaacuau caaacaucaa agaaaacaaa      300

ugcaacggca cagacgccaa aguaaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacag aucuacaaau gcucaugugc uccacaccag caaccggauc ugguucagcc      420

auagcauccg gcguagccgu cugcaaagua uuacaccucg aaggagaagu aaacaaaaua      480

aaaucugccc uauuaucuac aaauaaagcc guaguaaguc uaaguaacgg aguaucagua      540

cuaacauuua aaguccuaga ccugaaaaac uauaucgaca aacaacuauu accaauacua      600

aacaaacaau ccuguuccau cccuaaccca gaaacaguua uggaauuuca acaaaaaaau      660

aaccgccuuu uagaaauaac uagagaauuu ucaguaaacg caggaguuac aacaccagua      720

ucaacauaca ugcuaacaaa uucagaauua uuaucccuua uaaaugacau gccuaucaca      780

aacgaucaaa aaaaauuaau guccaacaac guacaaauag uaagacaaca aucauauucc      840

aucaugugca ucauaaaaga agaaguccuc gcauacguag ugcaacuacc acuauacgga      900

gucauagaua cacccuguug gaaacuucac acaucuccac uaugcacaac aaacacgaaa      960

gaaggaucca acauaugccu aacacgaaca gacagaggau gguauugcga caacgcugga     1020

agugugagcu ucuucccuca agcagaaacu ugcaaaguau gcagcaaucg uguauucugc     1080

gacacaauga acucauuaac acucccaagc gaaguaaacc ucugcaaugu agacaucuuu     1140

aauccaaaau acgauuguaa aauaaugacu ucaaaaacag acgucucauc aucuguaaua     1200

acaucuuuag gagcaauagu uucuugcuac gguaaaacaa aaugcaccgc auccaacaaa     1260

aacaaaggaa uaauaaaaac auucucuaac ggcugcgauu acguaucuaa caaaggaguu     1320

gacacagucu caguaggaaa cacacuauac uacguaaaca aacaagaagg acaaagccua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccau uaguauuucc aagcgaugaa     1440

uuugacgcuu caauaucaca agucaaugaa aaaauaaauc agagcuuagc auucauaaga     1500

aaaucugaug aacuacuaca caauguaaau gcaggaaaau ccacuaccaa cauaaugauu     1560

accacaauua uaauaguuau cauaguaaua cuauuaucac uaauagccgu uggauuacua     1620

cuauacugca aagcaagaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6545
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6545
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagca      120

aacgccauca ccaccauacu aaccgccguc accuucugcu ucgccucggg acaaaacauc      180

accgaagagu ucuaccaguc aacgugcucc gccgucucaa aaggcuaccu aggcgcccuc      240

cgcaccgggu gguauaccuc cgucauaacu aucgaacucu cuaacaucaa agaaaacaaa      300

uguaacggca ccgacgccaa agucaaacua aucaaacaag aacuggacaa auacaaaaac      360

gccgucaccg accuacaaau gcucaugugc uccacuccag ccaccggcuc cgguagcgca      420

aucgccucag gcguagcugu augcaaaguc cuccaccuag aaggcgaagu aaacaaaaua      480

aaauccgccc uccucucaac caacaaggcc gucgucucac ucucaaacgg cgucuccgua      540

cucaccuuua aaguccuaga ccuuaaaaac uacaucgaca aacaacugcu accaauccuc      600

aacaaacaau caugcagcau cccaaacccg gaaacaguca uggaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg ccggagucac cacaccugua      720

agcacauaca ugcuuacuaa uuccgaacuc cuuucacuaa uaaacgacau gccaauaacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uacgccaaca auccuacucc      840

aucaugugca ucaucaaaga agaaguccug gccuaugucg uacaacuccc ccuuuacggu      900

gucaucgaca cacccugcug gaaacuacac accagccccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccguacc gaccgaggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacc ugcaaagucu gcagcaaccg cgucuucugc     1080

gauaccauga acucccucac acucccaucu gaagucaacc ucugcaacgu cgauauuuuc     1140

aauccaaaau acgacugcaa aaucaugacu agcaaaaccg acguuagcuc cuccgucauc     1200

accucccucg gcgccauagu uucaugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac cuucuccaac gggugcgacu acguaucuaa uaaaggaguc     1320

gacaccgucu caguaggaaa cacccucuac uaugucaaca aacaagaagg ccaaucacua     1380

uacguuaaag gcgaaccaau caucaacuuc uacgacccac ucgucuuccc cagcgacgag     1440

uuugacgccu caaucucgca agucaaugaa aagauuaacc aaucccuagc cuucauccga     1500

aaaagugacg aacuccucca caacguuaac gccggcaaau cuacaaccaa caucaugauc     1560

accacuauaa ucaucgucau cauagucaua cuucucagcc ucaucgcagu cggacuccuc     1620

cuuuauugca aggcacgaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  6546
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6546
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6547
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6547
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6548
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6548
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6549
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6549
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6550
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6550
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6551
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6551
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6552
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6552
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auuaaaagca      120

aacgcaauaa caacgauauu aacagcugua acauucugcu uugcaucagg ccaaaauauc      180

accgaagaau uuuaucaaag cacaugcucu gcaguaucca aaggauacuu aggagcauua      240

agaacaggcu gguacacauc cguaauaaca auagaacuau caaacaucaa agaaaacaaa      300

ugcaacggca cagacgccaa aguaaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacag aucuacaaau gcucaugugc uccacaccag caaccggauc ugguucagcc      420

auagcauccg gcguagccgu cugcaaagua uuacaccucg aaggagaagu aaacaaaaua      480

aaaucugccc uauuaucuac aaauaaagcc guaguaaguc uaaguaacgg aguaucagua      540

cuaacauuua aaguccuaga ccugaaaaac uauaucgaca aacaacuauu accaauacua      600

aacaaacaau ccuguuccau cccuaaccca gaaacaguua uggaauuuca acaaaaaaau      660

aaccgccuuu uagaaauaac uagagaauuu ucaguaaacg caggaguuac aacaccagua      720

ucaacauaca ugcuaacaaa uucagaauua uuaucccuua uaaaugacau gccuaucaca      780

aacgaucaaa aaaaauuaau guccaacaac guacaaauag uaagacaaca aucauauucc      840

aucaugugca ucauaaaaga agaaguccuc gcauacguag ugcaacuacc acuauacgga      900

gucauagaua cacccuguug gaaacuucac acaucuccac uaugcacaac aaacacgaaa      960

gaaggaucca acauaugccu aacacgaaca gacagaggau gguauugcga caacgcugga     1020

agugugagcu ucuucccuca agcagaaacu ugcaaaguau gcagcaaucg uguauucugc     1080

gacacaauga acucauuaac acucccaagc gaaguaaacc ucugcaaugu agacaucuuu     1140

aauccaaaau acgauuguaa aauaaugacu ucaaaaacag acgucucauc aucuguaaua     1200

acaucuuuag gagcaauagu uucuugcuac gguaaaacaa aaugcaccgc auccaacaaa     1260

aacaaaggaa uaauaaaaac auucucuaac ggcugcgauu acguaucuaa caaaggaguu     1320

gacacagucu caguaggaaa cacacuauac uacguaaaca aacaagaagg acaaagccua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccau uaguauuucc aagcgaugaa     1440

uuugacgcuu caauaucaca agucaaugaa aaaauaaauc agagcuuagc auucauaaga     1500

aaaucugaug aacuacuaca caauguaaau gcaggaaaau ccacuaccaa cauaaugauu     1560

accacaauua uaauaguuau cauaguaaua cuauuaucac uaauagccgu uggauuacua     1620

cuauacugca aagcaagaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6553
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6553
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagca      120

aacgccauca ccaccauacu aaccgccguc accuucugcu ucgccucggg acaaaacauc      180

accgaagagu ucuaccaguc aacgugcucc gccgucucaa aaggcuaccu aggcgcccuc      240

cgcaccgggu gguauaccuc cgucauaacu aucgaacucu cuaacaucaa agaaaacaaa      300

uguaacggca ccgacgccaa agucaaacua aucaaacaag aacuggacaa auacaaaaac      360

gccgucaccg accuacaaau gcucaugugc uccacuccag ccaccggcuc cgguagcgca      420

aucgccucag gcguagcugu augcaaaguc cuccaccuag aaggcgaagu aaacaaaaua      480

aaauccgccc uccucucaac caacaaggcc gucgucucac ucucaaacgg cgucuccgua      540

cucaccuuua aaguccuaga ccuuaaaaac uacaucgaca aacaacugcu accaauccuc      600

aacaaacaau caugcagcau cccaaacccg gaaacaguca uggaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg ccggagucac cacaccugua      720

agcacauaca ugcuuacuaa uuccgaacuc cuuucacuaa uaaacgacau gccaauaacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uacgccaaca auccuacucc      840

aucaugugca ucaucaaaga agaaguccug gccuaugucg uacaacuccc ccuuuacggu      900

gucaucgaca cacccugcug gaaacuacac accagccccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccguacc gaccgaggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacc ugcaaagucu gcagcaaccg cgucuucugc     1080

gauaccauga acucccucac acucccaucu gaagucaacc ucugcaacgu cgauauuuuc     1140

aauccaaaau acgacugcaa aaucaugacu agcaaaaccg acguuagcuc cuccgucauc     1200

accucccucg gcgccauagu uucaugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac cuucuccaac gggugcgacu acguaucuaa uaaaggaguc     1320

gacaccgucu caguaggaaa cacccucuac uaugucaaca aacaagaagg ccaaucacua     1380

uacguuaaag gcgaaccaau caucaacuuc uacgacccac ucgucuuccc cagcgacgag     1440

uuugacgccu caaucucgca agucaaugaa aagauuaacc aaucccuagc cuucauccga     1500

aaaagugacg aacuccucca caacguuaac gccggcaaau cuacaaccaa caucaugauc     1560

accacuauaa ucaucgucau cauagucaua cuucucagcc ucaucgcagu cggacuccuc     1620

cuuuauugca aggcacgaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6554
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6554
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6555
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6555
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6556
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6556
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6557
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6557
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6558
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6558
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6559
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6559
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6560
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6560
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauuaaa agcaaacgca      120

auaacaacga uauuaacagc uguaacauuc ugcuuugcau caggccaaaa uaucaccgaa      180

gaauuuuauc aaagcacaug cucugcagua uccaaaggau acuuaggagc auuaagaaca      240

ggcugguaca cauccguaau aacaauagaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggcacagacg ccaaaguaaa acucauaaaa caagaacuag acaaauauaa aaacgcagua      360

acagaucuac aaaugcucau gugcuccaca ccagcaaccg gaucugguuc agccauagca      420

uccggcguag ccgucugcaa aguauuacac cucgaaggag aaguaaacaa aauaaaaucu      480

gcccuauuau cuacaaauaa agccguagua agucuaagua acggaguauc aguacuaaca      540

uuuaaagucc uagaccugaa aaacuauauc gacaaacaac uauuaccaau acuaaacaaa      600

caauccuguu ccaucccuaa cccagaaaca guuauggaau uucaacaaaa aaauaaccgc      660

cuuuuagaaa uaacuagaga auuuucagua aacgcaggag uuacaacacc aguaucaaca      720

uacaugcuaa caaauucaga auuauuaucc cuuauaaaug acaugccuau cacaaacgau      780

caaaaaaaau uaauguccaa caacguacaa auaguaagac aacaaucaua uuccaucaug      840

ugcaucauaa aagaagaagu ccucgcauac guagugcaac uaccacuaua cggagucaua      900

gauacacccu guuggaaacu ucacacaucu ccacuaugca caacaaacac gaaagaagga      960

uccaacauau gccuaacacg aacagacaga ggaugguauu gcgacaacgc uggaagugug     1020

agcuucuucc cucaagcaga aacuugcaaa guaugcagca aucguguauu cugcgacaca     1080

augaacucau uaacacuccc aagcgaagua aaccucugca auguagacau cuuuaaucca     1140

aaauacgauu guaaaauaau gacuucaaaa acagacgucu caucaucugu aauaacaucu     1200

uuaggagcaa uaguuucuug cuacgguaaa acaaaaugca ccgcauccaa caaaaacaaa     1260

ggaauaauaa aaacauucuc uaacggcugc gauuacguau cuaacaaagg aguugacaca     1320

gucucaguag gaaacacacu auacuacgua aacaaacaag aaggacaaag ccuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccauuaguau uuccaagcga ugaauuugac     1440

gcuucaauau cacaagucaa ugaaaaaaua aaucagagcu uagcauucau aagaaaaucu     1500

gaugaacuac uacacaaugu aaaugcagga aaauccacua ccaacauaau gauuaccaca     1560

auuauaauag uuaucauagu aauacuauua ucacuaauag ccguuggauu acuacuauac     1620

ugcaaagcaa gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6561
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6561
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agcaaacgcc      120

aucaccacca uacuaaccgc cgucaccuuc ugcuucgccu cgggacaaaa caucaccgaa      180

gaguucuacc agucaacgug cuccgccguc ucaaaaggcu accuaggcgc ccuccgcacc      240

gggugguaua ccuccgucau aacuaucgaa cucucuaaca ucaaagaaaa caaauguaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacugg acaaauacaa aaacgccguc      360

accgaccuac aaaugcucau gugcuccacu ccagccaccg gcuccgguag cgcaaucgcc      420

ucaggcguag cuguaugcaa aguccuccac cuagaaggcg aaguaaacaa aauaaaaucc      480

gcccuccucu caaccaacaa ggccgucguc ucacucucaa acggcgucuc cguacucacc      540

uuuaaagucc uagaccuuaa aaacuacauc gacaaacaac ugcuaccaau ccucaacaaa      600

caaucaugca gcaucccaaa cccggaaaca gucauggagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgccggag ucaccacacc uguaagcaca      720

uacaugcuua cuaauuccga acuccuuuca cuaauaaacg acaugccaau aaccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguacgcc aacaauccua cuccaucaug      840

ugcaucauca aagaagaagu ccuggccuau gucguacaac ucccccuuua cggugucauc      900

gacacacccu gcuggaaacu acacaccagc ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg uaccgaccga ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aaccugcaaa gucugcagca accgcgucuu cugcgauacc     1080

augaacuccc ucacacuccc aucugaaguc aaccucugca acgucgauau uuucaaucca     1140

aaauacgacu gcaaaaucau gacuagcaaa accgacguua gcuccuccgu caucaccucc     1200

cucggcgcca uaguuucaug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaaccuucuc caacgggugc gacuacguau cuaauaaagg agucgacacc     1320

gucucaguag gaaacacccu cuacuauguc aacaaacaag aaggccaauc acuauacguu     1380

aaaggcgaac caaucaucaa cuucuacgac ccacucgucu uccccagcga cgaguuugac     1440

gccucaaucu cgcaagucaa ugaaaagauu aaccaauccc uagccuucau ccgaaaaagu     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacaa ccaacaucau gaucaccacu     1560

auaaucaucg ucaucauagu cauacuucuc agccucaucg cagucggacu ccuccuuuau     1620

ugcaaggcac gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  6562
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6562
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6563
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6563
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6564
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6564
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6565
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6565
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6566
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6566
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6567
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6567
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6568
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6568
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauuaaaa      120

gcaaacgcaa uaacaacgau auuaacagcu guaacauucu gcuuugcauc aggccaaaau      180

aucaccgaag aauuuuauca aagcacaugc ucugcaguau ccaaaggaua cuuaggagca      240

uuaagaacag gcugguacac auccguaaua acaauagaac uaucaaacau caaagaaaac      300

aaaugcaacg gcacagacgc caaaguaaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cagaucuaca aaugcucaug ugcuccacac cagcaaccgg aucugguuca      420

gccauagcau ccggcguagc cgucugcaaa guauuacacc ucgaaggaga aguaaacaaa      480

auaaaaucug cccuauuauc uacaaauaaa gccguaguaa gucuaaguaa cggaguauca      540

guacuaacau uuaaaguccu agaccugaaa aacuauaucg acaaacaacu auuaccaaua      600

cuaaacaaac aauccuguuc caucccuaac ccagaaacag uuauggaauu ucaacaaaaa      660

aauaaccgcc uuuuagaaau aacuagagaa uuuucaguaa acgcaggagu uacaacacca      720

guaucaacau acaugcuaac aaauucagaa uuauuauccc uuauaaauga caugccuauc      780

acaaacgauc aaaaaaaauu aauguccaac aacguacaaa uaguaagaca acaaucauau      840

uccaucaugu gcaucauaaa agaagaaguc cucgcauacg uagugcaacu accacuauac      900

ggagucauag auacacccug uuggaaacuu cacacaucuc cacuaugcac aacaaacacg      960

aaagaaggau ccaacauaug ccuaacacga acagacagag gaugguauug cgacaacgcu     1020

ggaaguguga gcuucuuccc ucaagcagaa acuugcaaag uaugcagcaa ucguguauuc     1080

ugcgacacaa ugaacucauu aacacuccca agcgaaguaa accucugcaa uguagacauc     1140

uuuaauccaa aauacgauug uaaaauaaug acuucaaaaa cagacgucuc aucaucugua     1200

auaacaucuu uaggagcaau aguuucuugc uacgguaaaa caaaaugcac cgcauccaac     1260

aaaaacaaag gaauaauaaa aacauucucu aacggcugcg auuacguauc uaacaaagga     1320

guugacacag ucucaguagg aaacacacua uacuacguaa acaaacaaga aggacaaagc     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cauuaguauu uccaagcgau     1440

gaauuugacg cuucaauauc acaagucaau gaaaaaauaa aucagagcuu agcauucaua     1500

agaaaaucug augaacuacu acacaaugua aaugcaggaa aauccacuac caacauaaug     1560

auuaccacaa uuauaauagu uaucauagua auacuauuau cacuaauagc cguuggauua     1620

cuacuauacu gcaaagcaag auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6569
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6569
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gcaaacgcca ucaccaccau acuaaccgcc gucaccuucu gcuucgccuc gggacaaaac      180

aucaccgaag aguucuacca gucaacgugc uccgccgucu caaaaggcua ccuaggcgcc      240

cuccgcaccg ggugguauac cuccgucaua acuaucgaac ucucuaacau caaagaaaac      300

aaauguaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacugga caaauacaaa      360

aacgccguca ccgaccuaca aaugcucaug ugcuccacuc cagccaccgg cuccgguagc      420

gcaaucgccu caggcguagc uguaugcaaa guccuccacc uagaaggcga aguaaacaaa      480

auaaaauccg cccuccucuc aaccaacaag gccgucgucu cacucucaaa cggcgucucc      540

guacucaccu uuaaaguccu agaccuuaaa aacuacaucg acaaacaacu gcuaccaauc      600

cucaacaaac aaucaugcag caucccaaac ccggaaacag ucauggaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgccggagu caccacaccu      720

guaagcacau acaugcuuac uaauuccgaa cuccuuucac uaauaaacga caugccaaua      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguacgcca acaauccuac      840

uccaucaugu gcaucaucaa agaagaaguc cuggccuaug ucguacaacu cccccuuuac      900

ggugucaucg acacacccug cuggaaacua cacaccagcc cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgu accgaccgag gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa accugcaaag ucugcagcaa ccgcgucuuc     1080

ugcgauacca ugaacucccu cacacuccca ucugaaguca accucugcaa cgucgauauu     1140

uucaauccaa aauacgacug caaaaucaug acuagcaaaa ccgacguuag cuccuccguc     1200

aucaccuccc ucggcgccau aguuucaugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aaccuucucc aacgggugcg acuacguauc uaauaaagga     1320

gucgacaccg ucucaguagg aaacacccuc uacuauguca acaaacaaga aggccaauca     1380

cuauacguua aaggcgaacc aaucaucaac uucuacgacc cacucgucuu ccccagcgac     1440

gaguuugacg ccucaaucuc gcaagucaau gaaaagauua accaaucccu agccuucauc     1500

cgaaaaagug acgaacuccu ccacaacguu aacgccggca aaucuacaac caacaucaug     1560

aucaccacua uaaucaucgu caucauaguc auacuucuca gccucaucgc agucggacuc     1620

cuccuuuauu gcaaggcacg auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  6570
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6570
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6571
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6571
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6572
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6572
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6573
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6573
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6574
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6574
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6575
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6575
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6576
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6576
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauuaaa agcaaacgca      120

auaacaacga uauuaacagc uguaacauuc ugcuuugcau caggccaaaa uaucaccgaa      180

gaauuuuauc aaagcacaug cucugcagua uccaaaggau acuuaggagc auuaagaaca      240

ggcugguaca cauccguaau aacaauagaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggcacagacg ccaaaguaaa acucauaaaa caagaacuag acaaauauaa aaacgcagua      360

acagaucuac aaaugcucau gugcuccaca ccagcaaccg gaucugguuc agccauagca      420

uccggcguag ccgucugcaa aguauuacac cucgaaggag aaguaaacaa aauaaaaucu      480

gcccuauuau cuacaaauaa agccguagua agucuaagua acggaguauc aguacuaaca      540

uuuaaagucc uagaccugaa aaacuauauc gacaaacaac uauuaccaau acuaaacaaa      600

caauccuguu ccaucccuaa cccagaaaca guuauggaau uucaacaaaa aaauaaccgc      660

cuuuuagaaa uaacuagaga auuuucagua aacgcaggag uuacaacacc aguaucaaca      720

uacaugcuaa caaauucaga auuauuaucc cuuauaaaug acaugccuau cacaaacgau      780

caaaaaaaau uaauguccaa caacguacaa auaguaagac aacaaucaua uuccaucaug      840

ugcaucauaa aagaagaagu ccucgcauac guagugcaac uaccacuaua cggagucaua      900

gauacacccu guuggaaacu ucacacaucu ccacuaugca caacaaacac gaaagaagga      960

uccaacauau gccuaacacg aacagacaga ggaugguauu gcgacaacgc uggaagugug     1020

agcuucuucc cucaagcaga aacuugcaaa guaugcagca aucguguauu cugcgacaca     1080

augaacucau uaacacuccc aagcgaagua aaccucugca auguagacau cuuuaaucca     1140

aaauacgauu guaaaauaau gacuucaaaa acagacgucu caucaucugu aauaacaucu     1200

uuaggagcaa uaguuucuug cuacgguaaa acaaaaugca ccgcauccaa caaaaacaaa     1260

ggaauaauaa aaacauucuc uaacggcugc gauuacguau cuaacaaagg aguugacaca     1320

gucucaguag gaaacacacu auacuacgua aacaaacaag aaggacaaag ccuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccauuaguau uuccaagcga ugaauuugac     1440

gcuucaauau cacaagucaa ugaaaaaaua aaucagagcu uagcauucau aagaaaaucu     1500

gaugaacuac uacacaaugu aaaugcagga aaauccacua ccaacauaau gauuaccaca     1560

auuauaauag uuaucauagu aauacuauua ucacuaauag ccguuggauu acuacuauac     1620

ugcaaagcaa gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6577
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6577
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agcaaacgcc      120

aucaccacca uacuaaccgc cgucaccuuc ugcuucgccu cgggacaaaa caucaccgaa      180

gaguucuacc agucaacgug cuccgccguc ucaaaaggcu accuaggcgc ccuccgcacc      240

gggugguaua ccuccgucau aacuaucgaa cucucuaaca ucaaagaaaa caaauguaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacugg acaaauacaa aaacgccguc      360

accgaccuac aaaugcucau gugcuccacu ccagccaccg gcuccgguag cgcaaucgcc      420

ucaggcguag cuguaugcaa aguccuccac cuagaaggcg aaguaaacaa aauaaaaucc      480

gcccuccucu caaccaacaa ggccgucguc ucacucucaa acggcgucuc cguacucacc      540

uuuaaagucc uagaccuuaa aaacuacauc gacaaacaac ugcuaccaau ccucaacaaa      600

caaucaugca gcaucccaaa cccggaaaca gucauggagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgccggag ucaccacacc uguaagcaca      720

uacaugcuua cuaauuccga acuccuuuca cuaauaaacg acaugccaau aaccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguacgcc aacaauccua cuccaucaug      840

ugcaucauca aagaagaagu ccuggccuau gucguacaac ucccccuuua cggugucauc      900

gacacacccu gcuggaaacu acacaccagc ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg uaccgaccga ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aaccugcaaa gucugcagca accgcgucuu cugcgauacc     1080

augaacuccc ucacacuccc aucugaaguc aaccucugca acgucgauau uuucaaucca     1140

aaauacgacu gcaaaaucau gacuagcaaa accgacguua gcuccuccgu caucaccucc     1200

cucggcgcca uaguuucaug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaaccuucuc caacgggugc gacuacguau cuaauaaagg agucgacacc     1320

gucucaguag gaaacacccu cuacuauguc aacaaacaag aaggccaauc acuauacguu     1380

aaaggcgaac caaucaucaa cuucuacgac ccacucgucu uccccagcga cgaguuugac     1440

gccucaaucu cgcaagucaa ugaaaagauu aaccaauccc uagccuucau ccgaaaaagu     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacaa ccaacaucau gaucaccacu     1560

auaaucaucg ucaucauagu cauacuucuc agccucaucg cagucggacu ccuccuuuau     1620

ugcaaggcac gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  6578
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6578
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6579
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6579
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6580
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6580
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6581
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6581
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6582
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6582
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6583
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6583
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6584
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6584
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau uaaaagcaaa cgcaauaaca acgauauuaa cagcuguaac auucugcuuu      240

gcaucaggcc aaaauaucac cgaagaauuu uaucaaagca caugcucugc aguauccaaa      300

ggauacuuag gagcauuaag aacaggcugg uacacauccg uaauaacaau agaacuauca      360

aacaucaaag aaaacaaaug caacggcaca gacgccaaag uaaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacagau cuacaaaugc ucaugugcuc cacaccagca      480

accggaucug guucagccau agcauccggc guagccgucu gcaaaguauu acaccucgaa      540

ggagaaguaa acaaaauaaa aucugcccua uuaucuacaa auaaagccgu aguaagucua      600

aguaacggag uaucaguacu aacauuuaaa guccuagacc ugaaaaacua uaucgacaaa      660

caacuauuac caauacuaaa caaacaaucc uguuccaucc cuaacccaga aacaguuaug      720

gaauuucaac aaaaaaauaa ccgccuuuua gaaauaacua gagaauuuuc aguaaacgca      780

ggaguuacaa caccaguauc aacauacaug cuaacaaauu cagaauuauu aucccuuaua      840

aaugacaugc cuaucacaaa cgaucaaaaa aaauuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauauuccau caugugcauc auaaaagaag aaguccucgc auacguagug      960

caacuaccac uauacggagu cauagauaca cccuguugga aacuucacac aucuccacua     1020

ugcacaacaa acacgaaaga aggauccaac auaugccuaa cacgaacaga cagaggaugg     1080

uauugcgaca acgcuggaag ugugagcuuc uucccucaag cagaaacuug caaaguaugc     1140

agcaaucgug uauucugcga cacaaugaac ucauuaacac ucccaagcga aguaaaccuc     1200

ugcaauguag acaucuuuaa uccaaaauac gauuguaaaa uaaugacuuc aaaaacagac     1260

gucucaucau cuguaauaac aucuuuagga gcaauaguuu cuugcuacgg uaaaacaaaa     1320

ugcaccgcau ccaacaaaaa caaaggaaua auaaaaacau ucucuaacgg cugcgauuac     1380

guaucuaaca aaggaguuga cacagucuca guaggaaaca cacuauacua cguaaacaaa     1440

caagaaggac aaagccuaua cguaaaagga gaaccaauaa uaaacuucua ugacccauua     1500

guauuuccaa gcgaugaauu ugacgcuuca auaucacaag ucaaugaaaa aauaaaucag     1560

agcuuagcau ucauaagaaa aucugaugaa cuacuacaca auguaaaugc aggaaaaucc     1620

acuaccaaca uaaugauuac cacaauuaua auaguuauca uaguaauacu auuaucacua     1680

auagccguug gauuacuacu auacugcaaa gcaagauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6585
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6585
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagcaaa cgccaucacc accauacuaa ccgccgucac cuucugcuuc      240

gccucgggac aaaacaucac cgaagaguuc uaccagucaa cgugcuccgc cgucucaaaa      300

ggcuaccuag gcgcccuccg caccgggugg uauaccuccg ucauaacuau cgaacucucu      360

aacaucaaag aaaacaaaug uaacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cuggacaaau acaaaaacgc cgucaccgac cuacaaaugc ucaugugcuc cacuccagcc      480

accggcuccg guagcgcaau cgccucaggc guagcuguau gcaaaguccu ccaccuagaa      540

ggcgaaguaa acaaaauaaa auccgcccuc cucucaacca acaaggccgu cgucucacuc      600

ucaaacggcg ucuccguacu caccuuuaaa guccuagacc uuaaaaacua caucgacaaa      660

caacugcuac caauccucaa caaacaauca ugcagcaucc caaacccgga aacagucaug      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggagucacca caccuguaag cacauacaug cuuacuaauu ccgaacuccu uucacuaaua      840

aacgacaugc caauaaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucgua      900

cgccaacaau ccuacuccau caugugcauc aucaaagaag aaguccuggc cuaugucgua      960

caacuccccc uuuacggugu caucgacaca cccugcugga aacuacacac cagcccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccguaccga ccgaggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaaccug caaagucugc     1140

agcaaccgcg ucuucugcga uaccaugaac ucccucacac ucccaucuga agucaaccuc     1200

ugcaacgucg auauuuucaa uccaaaauac gacugcaaaa ucaugacuag caaaaccgac     1260

guuagcuccu ccgucaucac cucccucggc gccauaguuu caugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaaccu ucuccaacgg gugcgacuac     1380

guaucuaaua aaggagucga caccgucuca guaggaaaca cccucuacua ugucaacaaa     1440

caagaaggcc aaucacuaua cguuaaaggc gaaccaauca ucaacuucua cgacccacuc     1500

gucuucccca gcgacgaguu ugacgccuca aucucgcaag ucaaugaaaa gauuaaccaa     1560

ucccuagccu ucauccgaaa aagugacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

acaaccaaca ucaugaucac cacuauaauc aucgucauca uagucauacu ucucagccuc     1680

aucgcagucg gacuccuccu uuauugcaag gcacgauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  6586
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6586
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6587
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6587
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6588
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6588
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6589
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6589
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6590
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6590
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6591
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6591
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6592
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6592
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauuaaaagc aaacgcaaua acaacgauau      120

uaacagcugu aacauucugc uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa      180

gcacaugcuc ugcaguaucc aaaggauacu uaggagcauu aagaacaggc ugguacacau      240

ccguaauaac aauagaacua ucaaacauca aagaaaacaa augcaacggc acagacgcca      300

aaguaaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa      360

ugcucaugug cuccacacca gcaaccggau cugguucagc cauagcaucc ggcguagccg      420

ucugcaaagu auuacaccuc gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua      480

caaauaaagc cguaguaagu cuaaguaacg gaguaucagu acuaacauuu aaaguccuag      540

accugaaaaa cuauaucgac aaacaacuau uaccaauacu aaacaaacaa uccuguucca      600

ucccuaaccc agaaacaguu auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa      660

cuagagaauu uucaguaaac gcaggaguua caacaccagu aucaacauac augcuaacaa      720

auucagaauu auuaucccuu auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauauuc caucaugugc aucauaaaag      840

aagaaguccu cgcauacgua gugcaacuac cacuauacgg agucauagau acacccuguu      900

ggaaacuuca cacaucucca cuaugcacaa caaacacgaa agaaggaucc aacauaugcc      960

uaacacgaac agacagagga ugguauugcg acaacgcugg aagugugagc uucuucccuc     1020

aagcagaaac uugcaaagua ugcagcaauc guguauucug cgacacaaug aacucauuaa     1080

cacucccaag cgaaguaaac cucugcaaug uagacaucuu uaauccaaaa uacgauugua     1140

aaauaaugac uucaaaaaca gacgucucau caucuguaau aacaucuuua ggagcaauag     1200

uuucuugcua cgguaaaaca aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa     1260

cauucucuaa cggcugcgau uacguaucua acaaaggagu ugacacaguc ucaguaggaa     1320

acacacuaua cuacguaaac aaacaagaag gacaaagccu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca uuaguauuuc caagcgauga auuugacgcu ucaauaucac     1440

aagucaauga aaaaauaaau cagagcuuag cauucauaag aaaaucugau gaacuacuac     1500

acaauguaaa ugcaggaaaa uccacuacca acauaaugau uaccacaauu auaauaguua     1560

ucauaguaau acuauuauca cuaauagccg uuggauuacu acuauacugc aaagcaagau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6593
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6593
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc aaacgccauc accaccauac      120

uaaccgccgu caccuucugc uucgccucgg gacaaaacau caccgaagag uucuaccagu      180

caacgugcuc cgccgucuca aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu      240

ccgucauaac uaucgaacuc ucuaacauca aagaaaacaa auguaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa      360

ugcucaugug cuccacucca gccaccggcu ccgguagcgc aaucgccuca ggcguagcug      420

uaugcaaagu ccuccaccua gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa      480

ccaacaaggc cgucgucuca cucucaaacg gcgucuccgu acucaccuuu aaaguccuag      540

accuuaaaaa cuacaucgac aaacaacugc uaccaauccu caacaaacaa ucaugcagca      600

ucccaaaccc ggaaacaguc auggaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gccggaguca ccacaccugu aagcacauac augcuuacua      720

auuccgaacu ccuuucacua auaaacgaca ugccaauaac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guacgccaac aauccuacuc caucaugugc aucaucaaag      840

aagaaguccu ggccuauguc guacaacucc cccuuuacgg ugucaucgac acacccugcu      900

ggaaacuaca caccagcccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccguac cgaccgaggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac cugcaaaguc ugcagcaacc gcgucuucug cgauaccaug aacucccuca     1080

cacucccauc ugaagucaac cucugcaacg ucgauauuuu caauccaaaa uacgacugca     1140

aaaucaugac uagcaaaacc gacguuagcu ccuccgucau caccucccuc ggcgccauag     1200

uuucaugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

ccuucuccaa cgggugcgac uacguaucua auaaaggagu cgacaccguc ucaguaggaa     1320

acacccucua cuaugucaac aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa     1380

ucaucaacuu cuacgaccca cucgucuucc ccagcgacga guuugacgcc ucaaucucgc     1440

aagucaauga aaagauuaac caaucccuag ccuucauccg aaaaagugac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuacaacca acaucaugau caccacuaua aucaucguca     1560

ucauagucau acuucucagc cucaucgcag ucggacuccu ccuuuauugc aaggcacgau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6594
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6594
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6595
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6595
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6596
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6596
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6597
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6597
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6598
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6598
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6599
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6599
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6600
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6600
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau uaaaagcaaa cgcaauaaca acgauauuaa cagcuguaac auucugcuuu      240

gcaucaggcc aaaauaucac cgaagaauuu uaucaaagca caugcucugc aguauccaaa      300

ggauacuuag gagcauuaag aacaggcugg uacacauccg uaauaacaau agaacuauca      360

aacaucaaag aaaacaaaug caacggcaca gacgccaaag uaaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacagau cuacaaaugc ucaugugcuc cacaccagca      480

accggaucug guucagccau agcauccggc guagccgucu gcaaaguauu acaccucgaa      540

ggagaaguaa acaaaauaaa aucugcccua uuaucuacaa auaaagccgu aguaagucua      600

aguaacggag uaucaguacu aacauuuaaa guccuagacc ugaaaaacua uaucgacaaa      660

caacuauuac caauacuaaa caaacaaucc uguuccaucc cuaacccaga aacaguuaug      720

gaauuucaac aaaaaaauaa ccgccuuuua gaaauaacua gagaauuuuc aguaaacgca      780

ggaguuacaa caccaguauc aacauacaug cuaacaaauu cagaauuauu aucccuuaua      840

aaugacaugc cuaucacaaa cgaucaaaaa aaauuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauauuccau caugugcauc auaaaagaag aaguccucgc auacguagug      960

caacuaccac uauacggagu cauagauaca cccuguugga aacuucacac aucuccacua     1020

ugcacaacaa acacgaaaga aggauccaac auaugccuaa cacgaacaga cagaggaugg     1080

uauugcgaca acgcuggaag ugugagcuuc uucccucaag cagaaacuug caaaguaugc     1140

agcaaucgug uauucugcga cacaaugaac ucauuaacac ucccaagcga aguaaaccuc     1200

ugcaauguag acaucuuuaa uccaaaauac gauuguaaaa uaaugacuuc aaaaacagac     1260

gucucaucau cuguaauaac aucuuuagga gcaauaguuu cuugcuacgg uaaaacaaaa     1320

ugcaccgcau ccaacaaaaa caaaggaaua auaaaaacau ucucuaacgg cugcgauuac     1380

guaucuaaca aaggaguuga cacagucuca guaggaaaca cacuauacua cguaaacaaa     1440

caagaaggac aaagccuaua cguaaaagga gaaccaauaa uaaacuucua ugacccauua     1500

guauuuccaa gcgaugaauu ugacgcuuca auaucacaag ucaaugaaaa aauaaaucag     1560

agcuuagcau ucauaagaaa aucugaugaa cuacuacaca auguaaaugc aggaaaaucc     1620

acuaccaaca uaaugauuac cacaauuaua auaguuauca uaguaauacu auuaucacua     1680

auagccguug gauuacuacu auacugcaaa gcaagauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6601
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6601
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagcaaa cgccaucacc accauacuaa ccgccgucac cuucugcuuc      240

gccucgggac aaaacaucac cgaagaguuc uaccagucaa cgugcuccgc cgucucaaaa      300

ggcuaccuag gcgcccuccg caccgggugg uauaccuccg ucauaacuau cgaacucucu      360

aacaucaaag aaaacaaaug uaacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cuggacaaau acaaaaacgc cgucaccgac cuacaaaugc ucaugugcuc cacuccagcc      480

accggcuccg guagcgcaau cgccucaggc guagcuguau gcaaaguccu ccaccuagaa      540

ggcgaaguaa acaaaauaaa auccgcccuc cucucaacca acaaggccgu cgucucacuc      600

ucaaacggcg ucuccguacu caccuuuaaa guccuagacc uuaaaaacua caucgacaaa      660

caacugcuac caauccucaa caaacaauca ugcagcaucc caaacccgga aacagucaug      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggagucacca caccuguaag cacauacaug cuuacuaauu ccgaacuccu uucacuaaua      840

aacgacaugc caauaaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucgua      900

cgccaacaau ccuacuccau caugugcauc aucaaagaag aaguccuggc cuaugucgua      960

caacuccccc uuuacggugu caucgacaca cccugcugga aacuacacac cagcccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccguaccga ccgaggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaaccug caaagucugc     1140

agcaaccgcg ucuucugcga uaccaugaac ucccucacac ucccaucuga agucaaccuc     1200

ugcaacgucg auauuuucaa uccaaaauac gacugcaaaa ucaugacuag caaaaccgac     1260

guuagcuccu ccgucaucac cucccucggc gccauaguuu caugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaaccu ucuccaacgg gugcgacuac     1380

guaucuaaua aaggagucga caccgucuca guaggaaaca cccucuacua ugucaacaaa     1440

caagaaggcc aaucacuaua cguuaaaggc gaaccaauca ucaacuucua cgacccacuc     1500

gucuucccca gcgacgaguu ugacgccuca aucucgcaag ucaaugaaaa gauuaaccaa     1560

ucccuagccu ucauccgaaa aagugacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

acaaccaaca ucaugaucac cacuauaauc aucgucauca uagucauacu ucucagccuc     1680

aucgcagucg gacuccuccu uuauugcaag gcacgauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  6602
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6602
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6603
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6603
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      420

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      480

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      540

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      600

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      720

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc     1020

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1080

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1140

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1380

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1620

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6604
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6604
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      660

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6605
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6605
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      420

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      480

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      540

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      600

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      660

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      720

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      780

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      840

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua      900

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu      960

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg     1020

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1080

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1140

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1200

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1260

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1320

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1380

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1440

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1500

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1560

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1620

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6606
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6606
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      660

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6607
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6607
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      420

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      480

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      540

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      600

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      660

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      720

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      780

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      840

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug      900

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu      960

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc     1020

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1080

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1140

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1200

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1260

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1320

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1380

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1440

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1500

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1560

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1620

cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6608
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6608
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuca uauuaaaagc aaacgcaaua acaacgauau uaacagcugu aacauucugc      180

uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa gcacaugcuc ugcaguaucc      240

aaaggauacu uaggagcauu aagaacaggc ugguacacau ccguaauaac aauagaacua      300

ucaaacauca aagaaaacaa augcaacggc acagacgcca aaguaaaacu cauaaaacaa      360

gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa ugcucaugug cuccacacca      420

gcaaccggau cugguucagc cauagcaucc ggcguagccg ucugcaaagu auuacaccuc      480

gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua caaauaaagc cguaguaagu      540

cuaaguaacg gaguaucagu acuaacauuu aaaguccuag accugaaaaa cuauaucgac      600

aaacaacuau uaccaauacu aaacaaacaa uccuguucca ucccuaaccc agaaacaguu      660

auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa cuagagaauu uucaguaaac      720

gcaggaguua caacaccagu aucaacauac augcuaacaa auucagaauu auuaucccuu      780

auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa uguccaacaa cguacaaaua      840

guaagacaac aaucauauuc caucaugugc aucauaaaag aagaaguccu cgcauacgua      900

gugcaacuac cacuauacgg agucauagau acacccuguu ggaaacuuca cacaucucca      960

cuaugcacaa caaacacgaa agaaggaucc aacauaugcc uaacacgaac agacagagga     1020

ugguauugcg acaacgcugg aagugugagc uucuucccuc aagcagaaac uugcaaagua     1080

ugcagcaauc guguauucug cgacacaaug aacucauuaa cacucccaag cgaaguaaac     1140

cucugcaaug uagacaucuu uaauccaaaa uacgauugua aaauaaugac uucaaaaaca     1200

gacgucucau caucuguaau aacaucuuua ggagcaauag uuucuugcua cgguaaaaca     1260

aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa cauucucuaa cggcugcgau     1320

uacguaucua acaaaggagu ugacacaguc ucaguaggaa acacacuaua cuacguaaac     1380

aaacaagaag gacaaagccu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1440

uuaguauuuc caagcgauga auuugacgcu ucaauaucac aagucaauga aaaaauaaau     1500

cagagcuuag cauucauaag aaaaucugau gaacuacuac acaauguaaa ugcaggaaaa     1560

uccacuacca acauaaugau uaccacaauu auaauaguua ucauaguaau acuauuauca     1620

cuaauagccg uuggauuacu acuauacugc aaagcaagau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6609
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6609
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuca uccuaaaagc aaacgccauc accaccauac uaaccgccgu caccuucugc      180

uucgccucgg gacaaaacau caccgaagag uucuaccagu caacgugcuc cgccgucuca      240

aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu ccgucauaac uaucgaacuc      300

ucuaacauca aagaaaacaa auguaacggc accgacgcca aagucaaacu aaucaaacaa      360

gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa ugcucaugug cuccacucca      420

gccaccggcu ccgguagcgc aaucgccuca ggcguagcug uaugcaaagu ccuccaccua      480

gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa ccaacaaggc cgucgucuca      540

cucucaaacg gcgucuccgu acucaccuuu aaaguccuag accuuaaaaa cuacaucgac      600

aaacaacugc uaccaauccu caacaaacaa ucaugcagca ucccaaaccc ggaaacaguc      660

auggaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      720

gccggaguca ccacaccugu aagcacauac augcuuacua auuccgaacu ccuuucacua      780

auaaacgaca ugccaauaac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      840

guacgccaac aauccuacuc caucaugugc aucaucaaag aagaaguccu ggccuauguc      900

guacaacucc cccuuuacgg ugucaucgac acacccugcu ggaaacuaca caccagcccc      960

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccguac cgaccgaggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac cugcaaaguc     1080

ugcagcaacc gcgucuucug cgauaccaug aacucccuca cacucccauc ugaagucaac     1140

cucugcaacg ucgauauuuu caauccaaaa uacgacugca aaaucaugac uagcaaaacc     1200

gacguuagcu ccuccgucau caccucccuc ggcgccauag uuucaugcua cggcaaaacc     1260

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa ccuucuccaa cgggugcgac     1320

uacguaucua auaaaggagu cgacaccguc ucaguaggaa acacccucua cuaugucaac     1380

aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa ucaucaacuu cuacgaccca     1440

cucgucuucc ccagcgacga guuugacgcc ucaaucucgc aagucaauga aaagauuaac     1500

caaucccuag ccuucauccg aaaaagugac gaacuccucc acaacguuaa cgccggcaaa     1560

ucuacaacca acaucaugau caccacuaua aucaucguca ucauagucau acuucucagc     1620

cucaucgcag ucggacuccu ccuuuauugc aaggcacgau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  6610
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6610
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6611
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6611
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6612
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6612
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6613
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6613
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6614
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6614
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6615
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6615
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6616
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6616
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauuaaaa      120

gcaaacgcaa uaacaacgau auuaacagcu guaacauucu gcuuugcauc aggccaaaau      180

aucaccgaag aauuuuauca aagcacaugc ucugcaguau ccaaaggaua cuuaggagca      240

uuaagaacag gcugguacac auccguaaua acaauagaac uaucaaacau caaagaaaac      300

aaaugcaacg gcacagacgc caaaguaaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cagaucuaca aaugcucaug ugcuccacac cagcaaccgg aucugguuca      420

gccauagcau ccggcguagc cgucugcaaa guauuacacc ucgaaggaga aguaaacaaa      480

auaaaaucug cccuauuauc uacaaauaaa gccguaguaa gucuaaguaa cggaguauca      540

guacuaacau uuaaaguccu agaccugaaa aacuauaucg acaaacaacu auuaccaaua      600

cuaaacaaac aauccuguuc caucccuaac ccagaaacag uuauggaauu ucaacaaaaa      660

aauaaccgcc uuuuagaaau aacuagagaa uuuucaguaa acgcaggagu uacaacacca      720

guaucaacau acaugcuaac aaauucagaa uuauuauccc uuauaaauga caugccuauc      780

acaaacgauc aaaaaaaauu aauguccaac aacguacaaa uaguaagaca acaaucauau      840

uccaucaugu gcaucauaaa agaagaaguc cucgcauacg uagugcaacu accacuauac      900

ggagucauag auacacccug uuggaaacuu cacacaucuc cacuaugcac aacaaacacg      960

aaagaaggau ccaacauaug ccuaacacga acagacagag gaugguauug cgacaacgcu     1020

ggaaguguga gcuucuuccc ucaagcagaa acuugcaaag uaugcagcaa ucguguauuc     1080

ugcgacacaa ugaacucauu aacacuccca agcgaaguaa accucugcaa uguagacauc     1140

uuuaauccaa aauacgauug uaaaauaaug acuucaaaaa cagacgucuc aucaucugua     1200

auaacaucuu uaggagcaau aguuucuugc uacgguaaaa caaaaugcac cgcauccaac     1260

aaaaacaaag gaauaauaaa aacauucucu aacggcugcg auuacguauc uaacaaagga     1320

guugacacag ucucaguagg aaacacacua uacuacguaa acaaacaaga aggacaaagc     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cauuaguauu uccaagcgau     1440

gaauuugacg cuucaauauc acaagucaau gaaaaaauaa aucagagcuu agcauucaua     1500

agaaaaucug augaacuacu acacaaugua aaugcaggaa aauccacuac caacauaaug     1560

auuaccacaa uuauaauagu uaucauagua auacuauuau cacuaauagc cguuggauua     1620

cuacuauacu gcaaagcaag auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6617
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6617
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gcaaacgcca ucaccaccau acuaaccgcc gucaccuucu gcuucgccuc gggacaaaac      180

aucaccgaag aguucuacca gucaacgugc uccgccgucu caaaaggcua ccuaggcgcc      240

cuccgcaccg ggugguauac cuccgucaua acuaucgaac ucucuaacau caaagaaaac      300

aaauguaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacugga caaauacaaa      360

aacgccguca ccgaccuaca aaugcucaug ugcuccacuc cagccaccgg cuccgguagc      420

gcaaucgccu caggcguagc uguaugcaaa guccuccacc uagaaggcga aguaaacaaa      480

auaaaauccg cccuccucuc aaccaacaag gccgucgucu cacucucaaa cggcgucucc      540

guacucaccu uuaaaguccu agaccuuaaa aacuacaucg acaaacaacu gcuaccaauc      600

cucaacaaac aaucaugcag caucccaaac ccggaaacag ucauggaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgccggagu caccacaccu      720

guaagcacau acaugcuuac uaauuccgaa cuccuuucac uaauaaacga caugccaaua      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguacgcca acaauccuac      840

uccaucaugu gcaucaucaa agaagaaguc cuggccuaug ucguacaacu cccccuuuac      900

ggugucaucg acacacccug cuggaaacua cacaccagcc cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgu accgaccgag gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa accugcaaag ucugcagcaa ccgcgucuuc     1080

ugcgauacca ugaacucccu cacacuccca ucugaaguca accucugcaa cgucgauauu     1140

uucaauccaa aauacgacug caaaaucaug acuagcaaaa ccgacguuag cuccuccguc     1200

aucaccuccc ucggcgccau aguuucaugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aaccuucucc aacgggugcg acuacguauc uaauaaagga     1320

gucgacaccg ucucaguagg aaacacccuc uacuauguca acaaacaaga aggccaauca     1380

cuauacguua aaggcgaacc aaucaucaac uucuacgacc cacucgucuu ccccagcgac     1440

gaguuugacg ccucaaucuc gcaagucaau gaaaagauua accaaucccu agccuucauc     1500

cgaaaaagug acgaacuccu ccacaacguu aacgccggca aaucuacaac caacaucaug     1560

aucaccacua uaaucaucgu caucauaguc auacuucuca gccucaucgc agucggacuc     1620

cuccuuuauu gcaaggcacg auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  6618
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6618
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6619
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6619
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6620
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6620
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6621
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6621
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6622
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6622
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6623
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6623
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6624
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6624
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauuaaaa gcaaacgcaa uaacaacgau auuaacagcu      120

guaacauucu gcuuugcauc aggccaaaau aucaccgaag aauuuuauca aagcacaugc      180

ucugcaguau ccaaaggaua cuuaggagca uuaagaacag gcugguacac auccguaaua      240

acaauagaac uaucaaacau caaagaaaac aaaugcaacg gcacagacgc caaaguaaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguaa cagaucuaca aaugcucaug      360

ugcuccacac cagcaaccgg aucugguuca gccauagcau ccggcguagc cgucugcaaa      420

guauuacacc ucgaaggaga aguaaacaaa auaaaaucug cccuauuauc uacaaauaaa      480

gccguaguaa gucuaaguaa cggaguauca guacuaacau uuaaaguccu agaccugaaa      540

aacuauaucg acaaacaacu auuaccaaua cuaaacaaac aauccuguuc caucccuaac      600

ccagaaacag uuauggaauu ucaacaaaaa aauaaccgcc uuuuagaaau aacuagagaa      660

uuuucaguaa acgcaggagu uacaacacca guaucaacau acaugcuaac aaauucagaa      720

uuauuauccc uuauaaauga caugccuauc acaaacgauc aaaaaaaauu aauguccaac      780

aacguacaaa uaguaagaca acaaucauau uccaucaugu gcaucauaaa agaagaaguc      840

cucgcauacg uagugcaacu accacuauac ggagucauag auacacccug uuggaaacuu      900

cacacaucuc cacuaugcac aacaaacacg aaagaaggau ccaacauaug ccuaacacga      960

acagacagag gaugguauug cgacaacgcu ggaaguguga gcuucuuccc ucaagcagaa     1020

acuugcaaag uaugcagcaa ucguguauuc ugcgacacaa ugaacucauu aacacuccca     1080

agcgaaguaa accucugcaa uguagacauc uuuaauccaa aauacgauug uaaaauaaug     1140

acuucaaaaa cagacgucuc aucaucugua auaacaucuu uaggagcaau aguuucuugc     1200

uacgguaaaa caaaaugcac cgcauccaac aaaaacaaag gaauaauaaa aacauucucu     1260

aacggcugcg auuacguauc uaacaaagga guugacacag ucucaguagg aaacacacua     1320

uacuacguaa acaaacaaga aggacaaagc cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cauuaguauu uccaagcgau gaauuugacg cuucaauauc acaagucaau     1440

gaaaaaauaa aucagagcuu agcauucaua agaaaaucug augaacuacu acacaaugua     1500

aaugcaggaa aauccacuac caacauaaug auuaccacaa uuauaauagu uaucauagua     1560

auacuauuau cacuaauagc cguuggauua cuacuauacu gcaaagcaag auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6625
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6625
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gcaaacgcca ucaccaccau acuaaccgcc      120

gucaccuucu gcuucgccuc gggacaaaac aucaccgaag aguucuacca gucaacgugc      180

uccgccgucu caaaaggcua ccuaggcgcc cuccgcaccg ggugguauac cuccgucaua      240

acuaucgaac ucucuaacau caaagaaaac aaauguaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacugga caaauacaaa aacgccguca ccgaccuaca aaugcucaug      360

ugcuccacuc cagccaccgg cuccgguagc gcaaucgccu caggcguagc uguaugcaaa      420

guccuccacc uagaaggcga aguaaacaaa auaaaauccg cccuccucuc aaccaacaag      480

gccgucgucu cacucucaaa cggcgucucc guacucaccu uuaaaguccu agaccuuaaa      540

aacuacaucg acaaacaacu gcuaccaauc cucaacaaac aaucaugcag caucccaaac      600

ccggaaacag ucauggaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgccggagu caccacaccu guaagcacau acaugcuuac uaauuccgaa      720

cuccuuucac uaauaaacga caugccaaua accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguacgcca acaauccuac uccaucaugu gcaucaucaa agaagaaguc      840

cuggccuaug ucguacaacu cccccuuuac ggugucaucg acacacccug cuggaaacua      900

cacaccagcc cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgu      960

accgaccgag gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

accugcaaag ucugcagcaa ccgcgucuuc ugcgauacca ugaacucccu cacacuccca     1080

ucugaaguca accucugcaa cgucgauauu uucaauccaa aauacgacug caaaaucaug     1140

acuagcaaaa ccgacguuag cuccuccguc aucaccuccc ucggcgccau aguuucaugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aaccuucucc     1260

aacgggugcg acuacguauc uaauaaagga gucgacaccg ucucaguagg aaacacccuc     1320

uacuauguca acaaacaaga aggccaauca cuauacguua aaggcgaacc aaucaucaac     1380

uucuacgacc cacucgucuu ccccagcgac gaguuugacg ccucaaucuc gcaagucaau     1440

gaaaagauua accaaucccu agccuucauc cgaaaaagug acgaacuccu ccacaacguu     1500

aacgccggca aaucuacaac caacaucaug aucaccacua uaaucaucgu caucauaguc     1560

auacuucuca gccucaucgc agucggacuc cuccuuuauu gcaaggcacg auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  6626
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6626
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6627
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6627
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6628
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6628
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6629
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6629
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6630
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6630
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6631
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6631
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6632
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6632
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu aaaagcaaac gcaauaacaa cgauauuaac agcuguaaca      180

uucugcuuug caucaggcca aaauaucacc gaagaauuuu aucaaagcac augcucugca      240

guauccaaag gauacuuagg agcauuaaga acaggcuggu acacauccgu aauaacaaua      300

gaacuaucaa acaucaaaga aaacaaaugc aacggcacag acgccaaagu aaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacagauc uacaaaugcu caugugcucc      420

acaccagcaa ccggaucugg uucagccaua gcauccggcg uagccgucug caaaguauua      480

caccucgaag gagaaguaaa caaaauaaaa ucugcccuau uaucuacaaa uaaagccgua      540

guaagucuaa guaacggagu aucaguacua acauuuaaag uccuagaccu gaaaaacuau      600

aucgacaaac aacuauuacc aauacuaaac aaacaauccu guuccauccc uaacccagaa      660

acaguuaugg aauuucaaca aaaaaauaac cgccuuuuag aaauaacuag agaauuuuca      720

guaaacgcag gaguuacaac accaguauca acauacaugc uaacaaauuc agaauuauua      780

ucccuuauaa augacaugcc uaucacaaac gaucaaaaaa aauuaauguc caacaacgua      840

caaauaguaa gacaacaauc auauuccauc augugcauca uaaaagaaga aguccucgca      900

uacguagugc aacuaccacu auacggaguc auagauacac ccuguuggaa acuucacaca      960

ucuccacuau gcacaacaaa cacgaaagaa ggauccaaca uaugccuaac acgaacagac     1020

agaggauggu auugcgacaa cgcuggaagu gugagcuucu ucccucaagc agaaacuugc     1080

aaaguaugca gcaaucgugu auucugcgac acaaugaacu cauuaacacu cccaagcgaa     1140

guaaaccucu gcaauguaga caucuuuaau ccaaaauacg auuguaaaau aaugacuuca     1200

aaaacagacg ucucaucauc uguaauaaca ucuuuaggag caauaguuuc uugcuacggu     1260

aaaacaaaau gcaccgcauc caacaaaaac aaaggaauaa uaaaaacauu cucuaacggc     1320

ugcgauuacg uaucuaacaa aggaguugac acagucucag uaggaaacac acuauacuac     1380

guaaacaaac aagaaggaca aagccuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccauuag uauuuccaag cgaugaauuu gacgcuucaa uaucacaagu caaugaaaaa     1500

auaaaucaga gcuuagcauu cauaagaaaa ucugaugaac uacuacacaa uguaaaugca     1560

ggaaaaucca cuaccaacau aaugauuacc acaauuauaa uaguuaucau aguaauacua     1620

uuaucacuaa uagccguugg auuacuacua uacugcaaag caagauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6633
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6633
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagcaaac gccaucacca ccauacuaac cgccgucacc      180

uucugcuucg ccucgggaca aaacaucacc gaagaguucu accagucaac gugcuccgcc      240

gucucaaaag gcuaccuagg cgcccuccgc accggguggu auaccuccgu cauaacuauc      300

gaacucucua acaucaaaga aaacaaaugu aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac uggacaaaua caaaaacgcc gucaccgacc uacaaaugcu caugugcucc      420

acuccagcca ccggcuccgg uagcgcaauc gccucaggcg uagcuguaug caaaguccuc      480

caccuagaag gcgaaguaaa caaaauaaaa uccgcccucc ucucaaccaa caaggccguc      540

gucucacucu caaacggcgu cuccguacuc accuuuaaag uccuagaccu uaaaaacuac      600

aucgacaaac aacugcuacc aauccucaac aaacaaucau gcagcauccc aaacccggaa      660

acagucaugg aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgccg gagucaccac accuguaagc acauacaugc uuacuaauuc cgaacuccuu      780

ucacuaauaa acgacaugcc aauaaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguac gccaacaauc cuacuccauc augugcauca ucaaagaaga aguccuggcc      900

uaugucguac aacucccccu uuacgguguc aucgacacac ccugcuggaa acuacacacc      960

agcccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccguaccgac     1020

cgaggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaaccugc     1080

aaagucugca gcaaccgcgu cuucugcgau accaugaacu cccucacacu cccaucugaa     1140

gucaaccucu gcaacgucga uauuuucaau ccaaaauacg acugcaaaau caugacuagc     1200

aaaaccgacg uuagcuccuc cgucaucacc ucccucggcg ccauaguuuc augcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaaccuu cuccaacggg     1320

ugcgacuacg uaucuaauaa aggagucgac accgucucag uaggaaacac ccucuacuau     1380

gucaacaaac aagaaggcca aucacuauac guuaaaggcg aaccaaucau caacuucuac     1440

gacccacucg ucuuccccag cgacgaguuu gacgccucaa ucucgcaagu caaugaaaag     1500

auuaaccaau cccuagccuu cauccgaaaa agugacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua caaccaacau caugaucacc acuauaauca ucgucaucau agucauacuu     1620

cucagccuca ucgcagucgg acuccuccuu uauugcaagg cacgauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  6634
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6634
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6635
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6635
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6636
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6636
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6637
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6637
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6638
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6638
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6639
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6639
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6640
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6640
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauuaaa agcaaacgca      120

auaacaacga uauuaacagc uguaacauuc ugcuuugcau caggccaaaa uaucaccgaa      180

gaauuuuauc aaagcacaug cucugcagua uccaaaggau acuuaggagc auuaagaaca      240

ggcugguaca cauccguaau aacaauagaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggcacagacg ccaaaguaaa acucauaaaa caagaacuag acaaauauaa aaacgcagua      360

acagaucuac aaaugcucau gugcuccaca ccagcaaccg gaucugguuc agccauagca      420

uccggcguag ccgucugcaa aguauuacac cucgaaggag aaguaaacaa aauaaaaucu      480

gcccuauuau cuacaaauaa agccguagua agucuaagua acggaguauc aguacuaaca      540

uuuaaagucc uagaccugaa aaacuauauc gacaaacaac uauuaccaau acuaaacaaa      600

caauccuguu ccaucccuaa cccagaaaca guuauggaau uucaacaaaa aaauaaccgc      660

cuuuuagaaa uaacuagaga auuuucagua aacgcaggag uuacaacacc aguaucaaca      720

uacaugcuaa caaauucaga auuauuaucc cuuauaaaug acaugccuau cacaaacgau      780

caaaaaaaau uaauguccaa caacguacaa auaguaagac aacaaucaua uuccaucaug      840

ugcaucauaa aagaagaagu ccucgcauac guagugcaac uaccacuaua cggagucaua      900

gauacacccu guuggaaacu ucacacaucu ccacuaugca caacaaacac gaaagaagga      960

uccaacauau gccuaacacg aacagacaga ggaugguauu gcgacaacgc uggaagugug     1020

agcuucuucc cucaagcaga aacuugcaaa guaugcagca aucguguauu cugcgacaca     1080

augaacucau uaacacuccc aagcgaagua aaccucugca auguagacau cuuuaaucca     1140

aaauacgauu guaaaauaau gacuucaaaa acagacgucu caucaucugu aauaacaucu     1200

uuaggagcaa uaguuucuug cuacgguaaa acaaaaugca ccgcauccaa caaaaacaaa     1260

ggaauaauaa aaacauucuc uaacggcugc gauuacguau cuaacaaagg aguugacaca     1320

gucucaguag gaaacacacu auacuacgua aacaaacaag aaggacaaag ccuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccauuaguau uuccaagcga ugaauuugac     1440

gcuucaauau cacaagucaa ugaaaaaaua aaucagagcu uagcauucau aagaaaaucu     1500

gaugaacuac uacacaaugu aaaugcagga aaauccacua ccaacauaau gauuaccaca     1560

auuauaauag uuaucauagu aauacuauua ucacuaauag ccguuggauu acuacuauac     1620

ugcaaagcaa gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6641
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6641
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agcaaacgcc      120

aucaccacca uacuaaccgc cgucaccuuc ugcuucgccu cgggacaaaa caucaccgaa      180

gaguucuacc agucaacgug cuccgccguc ucaaaaggcu accuaggcgc ccuccgcacc      240

gggugguaua ccuccgucau aacuaucgaa cucucuaaca ucaaagaaaa caaauguaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacugg acaaauacaa aaacgccguc      360

accgaccuac aaaugcucau gugcuccacu ccagccaccg gcuccgguag cgcaaucgcc      420

ucaggcguag cuguaugcaa aguccuccac cuagaaggcg aaguaaacaa aauaaaaucc      480

gcccuccucu caaccaacaa ggccgucguc ucacucucaa acggcgucuc cguacucacc      540

uuuaaagucc uagaccuuaa aaacuacauc gacaaacaac ugcuaccaau ccucaacaaa      600

caaucaugca gcaucccaaa cccggaaaca gucauggagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgccggag ucaccacacc uguaagcaca      720

uacaugcuua cuaauuccga acuccuuuca cuaauaaacg acaugccaau aaccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguacgcc aacaauccua cuccaucaug      840

ugcaucauca aagaagaagu ccuggccuau gucguacaac ucccccuuua cggugucauc      900

gacacacccu gcuggaaacu acacaccagc ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg uaccgaccga ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aaccugcaaa gucugcagca accgcgucuu cugcgauacc     1080

augaacuccc ucacacuccc aucugaaguc aaccucugca acgucgauau uuucaaucca     1140

aaauacgacu gcaaaaucau gacuagcaaa accgacguua gcuccuccgu caucaccucc     1200

cucggcgcca uaguuucaug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaaccuucuc caacgggugc gacuacguau cuaauaaagg agucgacacc     1320

gucucaguag gaaacacccu cuacuauguc aacaaacaag aaggccaauc acuauacguu     1380

aaaggcgaac caaucaucaa cuucuacgac ccacucgucu uccccagcga cgaguuugac     1440

gccucaaucu cgcaagucaa ugaaaagauu aaccaauccc uagccuucau ccgaaaaagu     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacaa ccaacaucau gaucaccacu     1560

auaaucaucg ucaucauagu cauacuucuc agccucaucg cagucggacu ccuccuuuau     1620

ugcaaggcac gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  6642
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6642
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6643
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6643
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6644
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6644
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6645
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6645
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6646
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6646
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6647
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6647
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6648
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6648
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauuaaa agcaaacgca      120

auaacaacga uauuaacagc uguaacauuc ugcuuugcau caggccaaaa uaucaccgaa      180

gaauuuuauc aaagcacaug cucugcagua uccaaaggau acuuaggagc auuaagaaca      240

ggcugguaca cauccguaau aacaauagaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggcacagacg ccaaaguaaa acucauaaaa caagaacuag acaaauauaa aaacgcagua      360

acagaucuac aaaugcucau gugcuccaca ccagcaaccg gaucugguuc agccauagca      420

uccggcguag ccgucugcaa aguauuacac cucgaaggag aaguaaacaa aauaaaaucu      480

gcccuauuau cuacaaauaa agccguagua agucuaagua acggaguauc aguacuaaca      540

uuuaaagucc uagaccugaa aaacuauauc gacaaacaac uauuaccaau acuaaacaaa      600

caauccuguu ccaucccuaa cccagaaaca guuauggaau uucaacaaaa aaauaaccgc      660

cuuuuagaaa uaacuagaga auuuucagua aacgcaggag uuacaacacc aguaucaaca      720

uacaugcuaa caaauucaga auuauuaucc cuuauaaaug acaugccuau cacaaacgau      780

caaaaaaaau uaauguccaa caacguacaa auaguaagac aacaaucaua uuccaucaug      840

ugcaucauaa aagaagaagu ccucgcauac guagugcaac uaccacuaua cggagucaua      900

gauacacccu guuggaaacu ucacacaucu ccacuaugca caacaaacac gaaagaagga      960

uccaacauau gccuaacacg aacagacaga ggaugguauu gcgacaacgc uggaagugug     1020

agcuucuucc cucaagcaga aacuugcaaa guaugcagca aucguguauu cugcgacaca     1080

augaacucau uaacacuccc aagcgaagua aaccucugca auguagacau cuuuaaucca     1140

aaauacgauu guaaaauaau gacuucaaaa acagacgucu caucaucugu aauaacaucu     1200

uuaggagcaa uaguuucuug cuacgguaaa acaaaaugca ccgcauccaa caaaaacaaa     1260

ggaauaauaa aaacauucuc uaacggcugc gauuacguau cuaacaaagg aguugacaca     1320

gucucaguag gaaacacacu auacuacgua aacaaacaag aaggacaaag ccuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccauuaguau uuccaagcga ugaauuugac     1440

gcuucaauau cacaagucaa ugaaaaaaua aaucagagcu uagcauucau aagaaaaucu     1500

gaugaacuac uacacaaugu aaaugcagga aaauccacua ccaacauaau gauuaccaca     1560

auuauaauag uuaucauagu aauacuauua ucacuaauag ccguuggauu acuacuauac     1620

ugcaaagcaa gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6649
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6649
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agcaaacgcc      120

aucaccacca uacuaaccgc cgucaccuuc ugcuucgccu cgggacaaaa caucaccgaa      180

gaguucuacc agucaacgug cuccgccguc ucaaaaggcu accuaggcgc ccuccgcacc      240

gggugguaua ccuccgucau aacuaucgaa cucucuaaca ucaaagaaaa caaauguaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacugg acaaauacaa aaacgccguc      360

accgaccuac aaaugcucau gugcuccacu ccagccaccg gcuccgguag cgcaaucgcc      420

ucaggcguag cuguaugcaa aguccuccac cuagaaggcg aaguaaacaa aauaaaaucc      480

gcccuccucu caaccaacaa ggccgucguc ucacucucaa acggcgucuc cguacucacc      540

uuuaaagucc uagaccuuaa aaacuacauc gacaaacaac ugcuaccaau ccucaacaaa      600

caaucaugca gcaucccaaa cccggaaaca gucauggagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgccggag ucaccacacc uguaagcaca      720

uacaugcuua cuaauuccga acuccuuuca cuaauaaacg acaugccaau aaccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguacgcc aacaauccua cuccaucaug      840

ugcaucauca aagaagaagu ccuggccuau gucguacaac ucccccuuua cggugucauc      900

gacacacccu gcuggaaacu acacaccagc ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg uaccgaccga ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aaccugcaaa gucugcagca accgcgucuu cugcgauacc     1080

augaacuccc ucacacuccc aucugaaguc aaccucugca acgucgauau uuucaaucca     1140

aaauacgacu gcaaaaucau gacuagcaaa accgacguua gcuccuccgu caucaccucc     1200

cucggcgcca uaguuucaug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaaccuucuc caacgggugc gacuacguau cuaauaaagg agucgacacc     1320

gucucaguag gaaacacccu cuacuauguc aacaaacaag aaggccaauc acuauacguu     1380

aaaggcgaac caaucaucaa cuucuacgac ccacucgucu uccccagcga cgaguuugac     1440

gccucaaucu cgcaagucaa ugaaaagauu aaccaauccc uagccuucau ccgaaaaagu     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacaa ccaacaucau gaucaccacu     1560

auaaucaucg ucaucauagu cauacuucuc agccucaucg cagucggacu ccuccuuuau     1620

ugcaaggcac gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  6650
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6650
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6651
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6651
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6652
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6652
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6653
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6653
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6654
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6654
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6655
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6655
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6656
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6656
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauuaaa agcaaacgca      120

auaacaacga uauuaacagc uguaacauuc ugcuuugcau caggccaaaa uaucaccgaa      180

gaauuuuauc aaagcacaug cucugcagua uccaaaggau acuuaggagc auuaagaaca      240

ggcugguaca cauccguaau aacaauagaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggcacagacg ccaaaguaaa acucauaaaa caagaacuag acaaauauaa aaacgcagua      360

acagaucuac aaaugcucau gugcuccaca ccagcaaccg gaucugguuc agccauagca      420

uccggcguag ccgucugcaa aguauuacac cucgaaggag aaguaaacaa aauaaaaucu      480

gcccuauuau cuacaaauaa agccguagua agucuaagua acggaguauc aguacuaaca      540

uuuaaagucc uagaccugaa aaacuauauc gacaaacaac uauuaccaau acuaaacaaa      600

caauccuguu ccaucccuaa cccagaaaca guuauggaau uucaacaaaa aaauaaccgc      660

cuuuuagaaa uaacuagaga auuuucagua aacgcaggag uuacaacacc aguaucaaca      720

uacaugcuaa caaauucaga auuauuaucc cuuauaaaug acaugccuau cacaaacgau      780

caaaaaaaau uaauguccaa caacguacaa auaguaagac aacaaucaua uuccaucaug      840

ugcaucauaa aagaagaagu ccucgcauac guagugcaac uaccacuaua cggagucaua      900

gauacacccu guuggaaacu ucacacaucu ccacuaugca caacaaacac gaaagaagga      960

uccaacauau gccuaacacg aacagacaga ggaugguauu gcgacaacgc uggaagugug     1020

agcuucuucc cucaagcaga aacuugcaaa guaugcagca aucguguauu cugcgacaca     1080

augaacucau uaacacuccc aagcgaagua aaccucugca auguagacau cuuuaaucca     1140

aaauacgauu guaaaauaau gacuucaaaa acagacgucu caucaucugu aauaacaucu     1200

uuaggagcaa uaguuucuug cuacgguaaa acaaaaugca ccgcauccaa caaaaacaaa     1260

ggaauaauaa aaacauucuc uaacggcugc gauuacguau cuaacaaagg aguugacaca     1320

gucucaguag gaaacacacu auacuacgua aacaaacaag aaggacaaag ccuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccauuaguau uuccaagcga ugaauuugac     1440

gcuucaauau cacaagucaa ugaaaaaaua aaucagagcu uagcauucau aagaaaaucu     1500

gaugaacuac uacacaaugu aaaugcagga aaauccacua ccaacauaau gauuaccaca     1560

auuauaauag uuaucauagu aauacuauua ucacuaauag ccguuggauu acuacuauac     1620

ugcaaagcaa gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6657
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6657
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agcaaacgcc      120

aucaccacca uacuaaccgc cgucaccuuc ugcuucgccu cgggacaaaa caucaccgaa      180

gaguucuacc agucaacgug cuccgccguc ucaaaaggcu accuaggcgc ccuccgcacc      240

gggugguaua ccuccgucau aacuaucgaa cucucuaaca ucaaagaaaa caaauguaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacugg acaaauacaa aaacgccguc      360

accgaccuac aaaugcucau gugcuccacu ccagccaccg gcuccgguag cgcaaucgcc      420

ucaggcguag cuguaugcaa aguccuccac cuagaaggcg aaguaaacaa aauaaaaucc      480

gcccuccucu caaccaacaa ggccgucguc ucacucucaa acggcgucuc cguacucacc      540

uuuaaagucc uagaccuuaa aaacuacauc gacaaacaac ugcuaccaau ccucaacaaa      600

caaucaugca gcaucccaaa cccggaaaca gucauggagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgccggag ucaccacacc uguaagcaca      720

uacaugcuua cuaauuccga acuccuuuca cuaauaaacg acaugccaau aaccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguacgcc aacaauccua cuccaucaug      840

ugcaucauca aagaagaagu ccuggccuau gucguacaac ucccccuuua cggugucauc      900

gacacacccu gcuggaaacu acacaccagc ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg uaccgaccga ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aaccugcaaa gucugcagca accgcgucuu cugcgauacc     1080

augaacuccc ucacacuccc aucugaaguc aaccucugca acgucgauau uuucaaucca     1140

aaauacgacu gcaaaaucau gacuagcaaa accgacguua gcuccuccgu caucaccucc     1200

cucggcgcca uaguuucaug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaaccuucuc caacgggugc gacuacguau cuaauaaagg agucgacacc     1320

gucucaguag gaaacacccu cuacuauguc aacaaacaag aaggccaauc acuauacguu     1380

aaaggcgaac caaucaucaa cuucuacgac ccacucgucu uccccagcga cgaguuugac     1440

gccucaaucu cgcaagucaa ugaaaagauu aaccaauccc uagccuucau ccgaaaaagu     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacaa ccaacaucau gaucaccacu     1560

auaaucaucg ucaucauagu cauacuucuc agccucaucg cagucggacu ccuccuuuau     1620

ugcaaggcac gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  6658
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6658
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccauccccaa ccccgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6659
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6659
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agaugcucau gugcagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cuggaggggg aggugaacaa gaucaagagc      480

gcccuccugu ccaccaacaa ggccgugguc agccugucca acggcgugag cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

caguccugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccgggg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacuccga gcuccugagc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggcgugauc      900

gacacgcccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggg      960

agcaacaucu gccucacccg caccgaccgg ggcugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cgcaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggggcca ucguguccug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cgucgacacg     1320

guguccgugg ggaacacccu guacuacguc aacaagcagg agggccagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggc aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccguggggcu gcuccuguac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6660
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6660
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccauccccaa ccccgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6661
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6661
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugaccugc agaugcuuau guguuccaca cccgccaccg ggucuggauc ggcuauagca      420

ucaggcgugg ccgucugcaa ggugcugcac uuggagggug agguuaacaa aaucaagagc      480

gcucuccuga guacgaauaa agccgugguc ucccugucua acggggugag cguacucacu      540

uuuaagguuu uagaucugaa gaauuacauu gacaaacagc uuuugccuau ccugaacaag      600

caauccuguu caauuccaaa uccggaaacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa ucacacggga guuuaguguc aacgcgggag ugacuacccc cgugagcaca      720

uauaugcuga ccaauucuga gcuucugucc uugauaaacg auaugccuau uacgaacgac      780

cagaagaaac ucaugucaaa uaacguccaa aucguucgcc agcagagcua caguauuaug      840

ugcaucauca aggaagaggu gcuggcauau guagugcagu uaccacugua cggcgucauu      900

gauacucccu guuggaaacu ccauacaucu ccucuuugca ccacuaauac aaaggaaggc      960

uccaacauau gucugacccg aacggaccgu gggugguacu gcgauaaugc cggaagcgug     1020

ucguucuuuc cacaagcuga gaccuguaag guuugcucua acagaguguu cugcgacaca     1080

augaacuccu ugacucuacc cucagaaguc aaucugugua auguggauau cuuuaacccu     1140

aaauaugacu gcaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc     1200

cucggugcca uagugucaug uuacggcaag accaaaugca cagcaaguaa uaagaacaag     1260

gggauuauca aaaccuucuc caauggaugu gacuauguca gcaacaaggg cguggacacu     1320

gucucugugg guaauacgcu guacuauguu aacaaacagg aggggcaguc acuuuacgug     1380

aagggagagc caaucauuaa cuuuuaugau ccgcugguau uccccaguga cgaauuugau     1440

gcuagcaucu cccaagucaa ugagaaaauu aaccagucuu uggccuucau aaggaagucg     1500

gacgaacucc ugcacaaugu gaacgcgggc aagagcacaa ccaauaucau gauuacuacc     1560

aucaucauug uuauaaucgu gauuuuacug ucccuaaucg ccgucggccu ccugcuuuac     1620

ugcaaagcac ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6662
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6662
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcauccccaa ccccgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6663
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6663
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagaa uaaaugcaac      300

gggaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggaccucc agaugcugau guguagcacc cccgccacag gauccggcuc ugcuauugcc      420

agcggggucg cggugugcaa gguucugcac cucgagggag aggugaacaa aaucaagucc      480

gcccugcuua gcaccaauaa agcugucgug ucucugucca acggcguuag cgugcucaca      540

uuuaaggucc uggaucuuaa gaauuacauu gacaaacagc ugcucccuau ccugaacaag      600

caaucuuguu ccauuccgaa ucccgaaacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa ucacgcgcga guuuagcgug aacgccggcg ucacaacccc uguuucuaca      720

uauaugcuga ccaauuccga gcuucugagc cucauuaacg auaugcccau caccaacgac      780

cagaagaaac ugauguccaa uaacgugcaa aucgugagac agcagucuua cagcauuaug      840

ugcaucauua aggaagaggu ccuugcuuau gugguucagc ugccucucua cggggugauc      900

gauacacccu guuggaaacu gcauacgucc ccucugugca ccacaaauac caaggaagga      960

agcaacauuu gucucacacg gaccgaccgc ggcugguacu gcgauaaugc cgggucuguc     1020

uccuucuuuc cgcaagcgga gacguguaag gugugcagca acagaguuuu cugcgacaca     1080

augaacucuc ugacccuucc cagcgaagug aaucugugua augucgauau cuuuaacccu     1140

aaauaugacu gcaagaucau gaccuccaaa acagaugugu cuagcuccgu cauuaccagc     1200

cucggagcca ucgugucuug uuacggcaag acaaaaugca cggcuuccaa uaagaacaag     1260

gggauuauca aaaccuucag caauggaugu gacuauguuu cuaacaaggg cguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg aggggcagag ccuuuacgug     1380

aagggagagc ccauuaucaa cuuuuaugau ccucuggucu uccccuccga cgaauuugau     1440

gccucuauca gccaagugaa ugagaaaauu aaccaguccc ucgcuuucau ccggaagucu     1500

gacgaacugc ugcacaaugu gaacgccggc aagagcacaa ccaauauuau gaucacgacc     1560

auuaucauug uuaucaucgu cauucuccug ucccuuaucg ccguggggcu gcuccuguac     1620

ugcaaagcuc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6664
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6664
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauuaaa agcaaacgca      120

auaacaacga uauuaacagc uguaacauuc ugcuuugcau caggccaaaa uaucaccgaa      180

gaauuuuauc aaagcacaug cucugcagua uccaaaggau acuuaggagc auuaagaaca      240

ggcugguaca cauccguaau aacaauagaa cuaucaaaca ucaaagaaaa caaaugcaac      300

ggcacagacg ccaaaguaaa acucauaaaa caagaacuag acaaauauaa aaacgcagua      360

acagaucuac aaaugcucau gugcuccaca ccagcaaccg gaucugguuc agccauagca      420

uccggcguag ccgucugcaa aguauuacac cucgaaggag aaguaaacaa aauaaaaucu      480

gcccuauuau cuacaaauaa agccguagua agucuaagua acggaguauc aguacuaaca      540

uuuaaagucc uagaccugaa aaacuauauc gacaaacaac uauuaccaau acuaaacaaa      600

caauccuguu ccaucccuaa cccagaaaca guuauggaau uucaacaaaa aaauaaccgc      660

cuuuuagaaa uaacuagaga auuuucagua aacgcaggag uuacaacacc aguaucaaca      720

uacaugcuaa caaauucaga auuauuaucc cuuauaaaug acaugccuau cacaaacgau      780

caaaaaaaau uaauguccaa caacguacaa auaguaagac aacaaucaua uuccaucaug      840

ugcaucauaa aagaagaagu ccucgcauac guagugcaac uaccacuaua cggagucaua      900

gauacacccu guuggaaacu ucacacaucu ccacuaugca caacaaacac gaaagaagga      960

uccaacauau gccuaacacg aacagacaga ggaugguauu gcgacaacgc uggaagugug     1020

agcuucuucc cucaagcaga aacuugcaaa guaugcagca aucguguauu cugcgacaca     1080

augaacucau uaacacuccc aagcgaagua aaccucugca auguagacau cuuuaaucca     1140

aaauacgauu guaaaauaau gacuucaaaa acagacgucu caucaucugu aauaacaucu     1200

uuaggagcaa uaguuucuug cuacgguaaa acaaaaugca ccgcauccaa caaaaacaaa     1260

ggaauaauaa aaacauucuc uaacggcugc gauuacguau cuaacaaagg aguugacaca     1320

gucucaguag gaaacacacu auacuacgua aacaaacaag aaggacaaag ccuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccauuaguau uuccaagcga ugaauuugac     1440

gcuucaauau cacaagucaa ugaaaaaaua aaucagagcu uagcauucau aagaaaaucu     1500

gaugaacuac uacacaaugu aaaugcagga aaauccacua ccaacauaau gauuaccaca     1560

auuauaauag uuaucauagu aauacuauua ucacuaauag ccguuggauu acuacuauac     1620

ugcaaagcaa gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6665
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6665
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauccuaaa agcaaacgcc      120

aucaccacca uacuaaccgc cgucaccuuc ugcuucgccu cgggacaaaa caucaccgaa      180

gaguucuacc agucaacgug cuccgccguc ucaaaaggcu accuaggcgc ccuccgcacc      240

gggugguaua ccuccgucau aacuaucgaa cucucuaaca ucaaagaaaa caaauguaac      300

ggcaccgacg ccaaagucaa acuaaucaaa caagaacugg acaaauacaa aaacgccguc      360

accgaccuac aaaugcucau gugcuccacu ccagccaccg gcuccgguag cgcaaucgcc      420

ucaggcguag cuguaugcaa aguccuccac cuagaaggcg aaguaaacaa aauaaaaucc      480

gcccuccucu caaccaacaa ggccgucguc ucacucucaa acggcgucuc cguacucacc      540

uuuaaagucc uagaccuuaa aaacuacauc gacaaacaac ugcuaccaau ccucaacaaa      600

caaucaugca gcaucccaaa cccggaaaca gucauggagu uccaacagaa aaacaaccga      660

cuccucgaaa ucacccgcga guucuccguc aacgccggag ucaccacacc uguaagcaca      720

uacaugcuua cuaauuccga acuccuuuca cuaauaaacg acaugccaau aaccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguacgcc aacaauccua cuccaucaug      840

ugcaucauca aagaagaagu ccuggccuau gucguacaac ucccccuuua cggugucauc      900

gacacacccu gcuggaaacu acacaccagc ccccucugca caacaaacac caaagaaggc      960

uccaacaucu gccucacccg uaccgaccga ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaagccga aaccugcaaa gucugcagca accgcgucuu cugcgauacc     1080

augaacuccc ucacacuccc aucugaaguc aaccucugca acgucgauau uuucaaucca     1140

aaauacgacu gcaaaaucau gacuagcaaa accgacguua gcuccuccgu caucaccucc     1200

cucggcgcca uaguuucaug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaaccuucuc caacgggugc gacuacguau cuaauaaagg agucgacacc     1320

gucucaguag gaaacacccu cuacuauguc aacaaacaag aaggccaauc acuauacguu     1380

aaaggcgaac caaucaucaa cuucuacgac ccacucgucu uccccagcga cgaguuugac     1440

gccucaaucu cgcaagucaa ugaaaagauu aaccaauccc uagccuucau ccgaaaaagu     1500

gacgaacucc uccacaacgu uaacgccggc aaaucuacaa ccaacaucau gaucaccacu     1560

auaaucaucg ucaucauagu cauacuucuc agccucaucg cagucggacu ccuccuuuau     1620

ugcaaggcac gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  6666
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6666
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6667
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6667
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6668
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6668
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6669
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6669
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6670
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6670
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6671
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6671
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6672
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6672
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauuaaaagc aaacgcaaua acaacgauau      120

uaacagcugu aacauucugc uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa      180

gcacaugcuc ugcaguaucc aaaggauacu uaggagcauu aagaacaggc ugguacacau      240

ccguaauaac aauagaacua ucaaacauca aagaaaacaa augcaacggc acagacgcca      300

aaguaaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa      360

ugcucaugug cuccacacca gcaaccggau cugguucagc cauagcaucc ggcguagccg      420

ucugcaaagu auuacaccuc gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua      480

caaauaaagc cguaguaagu cuaaguaacg gaguaucagu acuaacauuu aaaguccuag      540

accugaaaaa cuauaucgac aaacaacuau uaccaauacu aaacaaacaa uccuguucca      600

ucccuaaccc agaaacaguu auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa      660

cuagagaauu uucaguaaac gcaggaguua caacaccagu aucaacauac augcuaacaa      720

auucagaauu auuaucccuu auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauauuc caucaugugc aucauaaaag      840

aagaaguccu cgcauacgua gugcaacuac cacuauacgg agucauagau acacccuguu      900

ggaaacuuca cacaucucca cuaugcacaa caaacacgaa agaaggaucc aacauaugcc      960

uaacacgaac agacagagga ugguauugcg acaacgcugg aagugugagc uucuucccuc     1020

aagcagaaac uugcaaagua ugcagcaauc guguauucug cgacacaaug aacucauuaa     1080

cacucccaag cgaaguaaac cucugcaaug uagacaucuu uaauccaaaa uacgauugua     1140

aaauaaugac uucaaaaaca gacgucucau caucuguaau aacaucuuua ggagcaauag     1200

uuucuugcua cgguaaaaca aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa     1260

cauucucuaa cggcugcgau uacguaucua acaaaggagu ugacacaguc ucaguaggaa     1320

acacacuaua cuacguaaac aaacaagaag gacaaagccu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca uuaguauuuc caagcgauga auuugacgcu ucaauaucac     1440

aagucaauga aaaaauaaau cagagcuuag cauucauaag aaaaucugau gaacuacuac     1500

acaauguaaa ugcaggaaaa uccacuacca acauaaugau uaccacaauu auaauaguua     1560

ucauaguaau acuauuauca cuaauagccg uuggauuacu acuauacugc aaagcaagau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6673
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6673
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc aaacgccauc accaccauac      120

uaaccgccgu caccuucugc uucgccucgg gacaaaacau caccgaagag uucuaccagu      180

caacgugcuc cgccgucuca aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu      240

ccgucauaac uaucgaacuc ucuaacauca aagaaaacaa auguaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa      360

ugcucaugug cuccacucca gccaccggcu ccgguagcgc aaucgccuca ggcguagcug      420

uaugcaaagu ccuccaccua gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa      480

ccaacaaggc cgucgucuca cucucaaacg gcgucuccgu acucaccuuu aaaguccuag      540

accuuaaaaa cuacaucgac aaacaacugc uaccaauccu caacaaacaa ucaugcagca      600

ucccaaaccc ggaaacaguc auggaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gccggaguca ccacaccugu aagcacauac augcuuacua      720

auuccgaacu ccuuucacua auaaacgaca ugccaauaac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guacgccaac aauccuacuc caucaugugc aucaucaaag      840

aagaaguccu ggccuauguc guacaacucc cccuuuacgg ugucaucgac acacccugcu      900

ggaaacuaca caccagcccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccguac cgaccgaggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac cugcaaaguc ugcagcaacc gcgucuucug cgauaccaug aacucccuca     1080

cacucccauc ugaagucaac cucugcaacg ucgauauuuu caauccaaaa uacgacugca     1140

aaaucaugac uagcaaaacc gacguuagcu ccuccgucau caccucccuc ggcgccauag     1200

uuucaugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

ccuucuccaa cgggugcgac uacguaucua auaaaggagu cgacaccguc ucaguaggaa     1320

acacccucua cuaugucaac aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa     1380

ucaucaacuu cuacgaccca cucgucuucc ccagcgacga guuugacgcc ucaaucucgc     1440

aagucaauga aaagauuaac caaucccuag ccuucauccg aaaaagugac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuacaacca acaucaugau caccacuaua aucaucguca     1560

ucauagucau acuucucagc cucaucgcag ucggacuccu ccuuuauugc aaggcacgau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  6674
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6674
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

uccccaaccc cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6675
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6675
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcaga      360

ugcucaugug cagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggggagg ugaacaagau caagagcgcc cuccugucca      480

ccaacaaggc cguggucagc cuguccaacg gcgugagcgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag uccugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccgggguca ccacgcccgu gagcaccuac augcugacca      720

acuccgagcu ccugagccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg cgugaucgac acgcccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggaggggagc aacaucugcc      960

ucacccgcac cgaccggggc ugguacugcg acaacgcggg cuccgugagc uucuucccgc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggggccaucg     1200

uguccugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu cgacacggug uccgugggga     1320

acacccugua cuacgucaac aagcaggagg gccagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccggcaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg uggggcugcu ccuguacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6676
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6676
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

uccccaaccc cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gccagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6677
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6677
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaauaa augcaacggc accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga      360

ugcuuaugug uuccacaccc gccaccgggu cuggaucggc uauagcauca ggcguggccg      420

ucugcaaggu gcugcacuug gagggugagg uuaacaaaau caagagcgcu cuccugagua      480

cgaauaaagc cguggucucc cugucuaacg gggugagcgu acucacuuuu aagguuuuag      540

aucugaagaa uuacauugac aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa      600

uuccaaaucc ggaaaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauca      660

cacgggaguu uagugucaac gcgggaguga cuacccccgu gagcacauau augcugacca      720

auucugagcu ucuguccuug auaaacgaua ugccuauuac gaacgaccag aagaaacuca      780

ugucaaauaa cguccaaauc guucgccagc agagcuacag uauuaugugc aucaucaagg      840

aagaggugcu ggcauaugua gugcaguuac cacuguacgg cgucauugau acucccuguu      900

ggaaacucca uacaucuccu cuuugcacca cuaauacaaa ggaaggcucc aacauauguc      960

ugacccgaac ggaccguggg ugguacugcg auaaugccgg aagcgugucg uucuuuccac     1020

aagcugagac cuguaagguu ugcucuaaca gaguguucug cgacacaaug aacuccuuga     1080

cucuacccuc agaagucaau cuguguaaug uggauaucuu uaacccuaaa uaugacugca     1140

agauuaugac caguaaaaca gauguaagcu ccucuguuau cacuagccuc ggugccauag     1200

ugucauguua cggcaagacc aaaugcacag caaguaauaa gaacaagggg auuaucaaaa     1260

ccuucuccaa uggaugugac uaugucagca acaagggcgu ggacacuguc ucugugggua     1320

auacgcugua cuauguuaac aaacaggagg ggcagucacu uuacgugaag ggagagccaa     1380

ucauuaacuu uuaugauccg cugguauucc ccagugacga auuugaugcu agcaucuccc     1440

aagucaauga gaaaauuaac cagucuuugg ccuucauaag gaagucggac gaacuccugc     1500

acaaugugaa cgcgggcaag agcacaacca auaucaugau uacuaccauc aucauuguua     1560

uaaucgugau uuuacugucc cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6678
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6678
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

uccccaaccc cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gccagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6679
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6679
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaauaa augcaacggg accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gaccuccaga      360

ugcugaugug uagcaccccc gccacaggau ccggcucugc uauugccagc ggggucgcgg      420

ugugcaaggu ucugcaccuc gagggagagg ugaacaaaau caaguccgcc cugcuuagca      480

ccaauaaagc ugucgugucu cuguccaacg gcguuagcgu gcucacauuu aagguccugg      540

aucuuaagaa uuacauugac aaacagcugc ucccuauccu gaacaagcaa ucuuguucca      600

uuccgaaucc cgaaaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauca      660

cgcgcgaguu uagcgugaac gccggcguca caaccccugu uucuacauau augcugacca      720

auuccgagcu ucugagccuc auuaacgaua ugcccaucac caacgaccag aagaaacuga      780

uguccaauaa cgugcaaauc gugagacagc agucuuacag cauuaugugc aucauuaagg      840

aagagguccu ugcuuaugug guucagcugc cucucuacgg ggugaucgau acacccuguu      900

ggaaacugca uacguccccu cugugcacca caaauaccaa ggaaggaagc aacauuuguc      960

ucacacggac cgaccgcggc ugguacugcg auaaugccgg gucugucucc uucuuuccgc     1020

aagcggagac guguaaggug ugcagcaaca gaguuuucug cgacacaaug aacucucuga     1080

cccuucccag cgaagugaau cuguguaaug ucgauaucuu uaacccuaaa uaugacugca     1140

agaucaugac cuccaaaaca gaugugucua gcuccgucau uaccagccuc ggagccaucg     1200

ugucuuguua cggcaagaca aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa     1260

ccuucagcaa uggaugugac uauguuucua acaagggcgu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg ggcagagccu uuacgugaag ggagagccca     1380

uuaucaacuu uuaugauccu cuggucuucc ccuccgacga auuugaugcc ucuaucagcc     1440

aagugaauga gaaaauuaac cagucccucg cuuucauccg gaagucugac gaacugcugc     1500

acaaugugaa cgccggcaag agcacaacca auauuaugau cacgaccauu aucauuguua     1560

ucaucgucau ucuccugucc cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6680
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6680
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauuaaaagc aaacgcaaua acaacgauau      120

uaacagcugu aacauucugc uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa      180

gcacaugcuc ugcaguaucc aaaggauacu uaggagcauu aagaacaggc ugguacacau      240

ccguaauaac aauagaacua ucaaacauca aagaaaacaa augcaacggc acagacgcca      300

aaguaaaacu cauaaaacaa gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa      360

ugcucaugug cuccacacca gcaaccggau cugguucagc cauagcaucc ggcguagccg      420

ucugcaaagu auuacaccuc gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua      480

caaauaaagc cguaguaagu cuaaguaacg gaguaucagu acuaacauuu aaaguccuag      540

accugaaaaa cuauaucgac aaacaacuau uaccaauacu aaacaaacaa uccuguucca      600

ucccuaaccc agaaacaguu auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa      660

cuagagaauu uucaguaaac gcaggaguua caacaccagu aucaacauac augcuaacaa      720

auucagaauu auuaucccuu auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa      780

uguccaacaa cguacaaaua guaagacaac aaucauauuc caucaugugc aucauaaaag      840

aagaaguccu cgcauacgua gugcaacuac cacuauacgg agucauagau acacccuguu      900

ggaaacuuca cacaucucca cuaugcacaa caaacacgaa agaaggaucc aacauaugcc      960

uaacacgaac agacagagga ugguauugcg acaacgcugg aagugugagc uucuucccuc     1020

aagcagaaac uugcaaagua ugcagcaauc guguauucug cgacacaaug aacucauuaa     1080

cacucccaag cgaaguaaac cucugcaaug uagacaucuu uaauccaaaa uacgauugua     1140

aaauaaugac uucaaaaaca gacgucucau caucuguaau aacaucuuua ggagcaauag     1200

uuucuugcua cgguaaaaca aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa     1260

cauucucuaa cggcugcgau uacguaucua acaaaggagu ugacacaguc ucaguaggaa     1320

acacacuaua cuacguaaac aaacaagaag gacaaagccu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca uuaguauuuc caagcgauga auuugacgcu ucaauaucac     1440

aagucaauga aaaaauaaau cagagcuuag cauucauaag aaaaucugau gaacuacuac     1500

acaauguaaa ugcaggaaaa uccacuacca acauaaugau uaccacaauu auaauaguua     1560

ucauaguaau acuauuauca cuaauagccg uuggauuacu acuauacugc aaagcaagau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6681
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6681
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uccuaaaagc aaacgccauc accaccauac      120

uaaccgccgu caccuucugc uucgccucgg gacaaaacau caccgaagag uucuaccagu      180

caacgugcuc cgccgucuca aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu      240

ccgucauaac uaucgaacuc ucuaacauca aagaaaacaa auguaacggc accgacgcca      300

aagucaaacu aaucaaacaa gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa      360

ugcucaugug cuccacucca gccaccggcu ccgguagcgc aaucgccuca ggcguagcug      420

uaugcaaagu ccuccaccua gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa      480

ccaacaaggc cgucgucuca cucucaaacg gcgucuccgu acucaccuuu aaaguccuag      540

accuuaaaaa cuacaucgac aaacaacugc uaccaauccu caacaaacaa ucaugcagca      600

ucccaaaccc ggaaacaguc auggaguucc aacagaaaaa caaccgacuc cucgaaauca      660

cccgcgaguu cuccgucaac gccggaguca ccacaccugu aagcacauac augcuuacua      720

auuccgaacu ccuuucacua auaaacgaca ugccaauaac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guacgccaac aauccuacuc caucaugugc aucaucaaag      840

aagaaguccu ggccuauguc guacaacucc cccuuuacgg ugucaucgac acacccugcu      900

ggaaacuaca caccagcccc cucugcacaa caaacaccaa agaaggcucc aacaucugcc      960

ucacccguac cgaccgaggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aagccgaaac cugcaaaguc ugcagcaacc gcgucuucug cgauaccaug aacucccuca     1080

cacucccauc ugaagucaac cucugcaacg ucgauauuuu caauccaaaa uacgacugca     1140

aaaucaugac uagcaaaacc gacguuagcu ccuccgucau caccucccuc ggcgccauag     1200

uuucaugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

ccuucuccaa cgggugcgac uacguaucua auaaaggagu cgacaccguc ucaguaggaa     1320

acacccucua cuaugucaac aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa     1380

ucaucaacuu cuacgaccca cucgucuucc ccagcgacga guuugacgcc ucaaucucgc     1440

aagucaauga aaagauuaac caaucccuag ccuucauccg aaaaagugac gaacuccucc     1500

acaacguuaa cgccggcaaa ucuacaacca acaucaugau caccacuaua aucaucguca     1560

ucauagucau acuucucagc cucaucgcag ucggacuccu ccuuuauugc aaggcacgau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  6682
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6682
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6683
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6683
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6684
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6684
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6685
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6685
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6686
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6686
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6687
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6687
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6688
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6688
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauuaaaa gcaaacgcaa uaacaacgau auuaacagcu      120

guaacauucu gcuuugcauc aggccaaaau aucaccgaag aauuuuauca aagcacaugc      180

ucugcaguau ccaaaggaua cuuaggagca uuaagaacag gcugguacac auccguaaua      240

acaauagaac uaucaaacau caaagaaaac aaaugcaacg gcacagacgc caaaguaaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguaa cagaucuaca aaugcucaug      360

ugcuccacac cagcaaccgg aucugguuca gccauagcau ccggcguagc cgucugcaaa      420

guauuacacc ucgaaggaga aguaaacaaa auaaaaucug cccuauuauc uacaaauaaa      480

gccguaguaa gucuaaguaa cggaguauca guacuaacau uuaaaguccu agaccugaaa      540

aacuauaucg acaaacaacu auuaccaaua cuaaacaaac aauccuguuc caucccuaac      600

ccagaaacag uuauggaauu ucaacaaaaa aauaaccgcc uuuuagaaau aacuagagaa      660

uuuucaguaa acgcaggagu uacaacacca guaucaacau acaugcuaac aaauucagaa      720

uuauuauccc uuauaaauga caugccuauc acaaacgauc aaaaaaaauu aauguccaac      780

aacguacaaa uaguaagaca acaaucauau uccaucaugu gcaucauaaa agaagaaguc      840

cucgcauacg uagugcaacu accacuauac ggagucauag auacacccug uuggaaacuu      900

cacacaucuc cacuaugcac aacaaacacg aaagaaggau ccaacauaug ccuaacacga      960

acagacagag gaugguauug cgacaacgcu ggaaguguga gcuucuuccc ucaagcagaa     1020

acuugcaaag uaugcagcaa ucguguauuc ugcgacacaa ugaacucauu aacacuccca     1080

agcgaaguaa accucugcaa uguagacauc uuuaauccaa aauacgauug uaaaauaaug     1140

acuucaaaaa cagacgucuc aucaucugua auaacaucuu uaggagcaau aguuucuugc     1200

uacgguaaaa caaaaugcac cgcauccaac aaaaacaaag gaauaauaaa aacauucucu     1260

aacggcugcg auuacguauc uaacaaagga guugacacag ucucaguagg aaacacacua     1320

uacuacguaa acaaacaaga aggacaaagc cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cauuaguauu uccaagcgau gaauuugacg cuucaauauc acaagucaau     1440

gaaaaaauaa aucagagcuu agcauucaua agaaaaucug augaacuacu acacaaugua     1500

aaugcaggaa aauccacuac caacauaaug auuaccacaa uuauaauagu uaucauagua     1560

auacuauuau cacuaauagc cguuggauua cuacuauacu gcaaagcaag auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6689
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6689
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gcaaacgcca ucaccaccau acuaaccgcc      120

gucaccuucu gcuucgccuc gggacaaaac aucaccgaag aguucuacca gucaacgugc      180

uccgccgucu caaaaggcua ccuaggcgcc cuccgcaccg ggugguauac cuccgucaua      240

acuaucgaac ucucuaacau caaagaaaac aaauguaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacugga caaauacaaa aacgccguca ccgaccuaca aaugcucaug      360

ugcuccacuc cagccaccgg cuccgguagc gcaaucgccu caggcguagc uguaugcaaa      420

guccuccacc uagaaggcga aguaaacaaa auaaaauccg cccuccucuc aaccaacaag      480

gccgucgucu cacucucaaa cggcgucucc guacucaccu uuaaaguccu agaccuuaaa      540

aacuacaucg acaaacaacu gcuaccaauc cucaacaaac aaucaugcag caucccaaac      600

ccggaaacag ucauggaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgccggagu caccacaccu guaagcacau acaugcuuac uaauuccgaa      720

cuccuuucac uaauaaacga caugccaaua accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguacgcca acaauccuac uccaucaugu gcaucaucaa agaagaaguc      840

cuggccuaug ucguacaacu cccccuuuac ggugucaucg acacacccug cuggaaacua      900

cacaccagcc cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgu      960

accgaccgag gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

accugcaaag ucugcagcaa ccgcgucuuc ugcgauacca ugaacucccu cacacuccca     1080

ucugaaguca accucugcaa cgucgauauu uucaauccaa aauacgacug caaaaucaug     1140

acuagcaaaa ccgacguuag cuccuccguc aucaccuccc ucggcgccau aguuucaugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aaccuucucc     1260

aacgggugcg acuacguauc uaauaaagga gucgacaccg ucucaguagg aaacacccuc     1320

uacuauguca acaaacaaga aggccaauca cuauacguua aaggcgaacc aaucaucaac     1380

uucuacgacc cacucgucuu ccccagcgac gaguuugacg ccucaaucuc gcaagucaau     1440

gaaaagauua accaaucccu agccuucauc cgaaaaagug acgaacuccu ccacaacguu     1500

aacgccggca aaucuacaac caacaucaug aucaccacua uaaucaucgu caucauaguc     1560

auacuucuca gccucaucgc agucggacuc cuccuuuauu gcaaggcacg auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  6690
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6690
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc cauccccaac      600

cccgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6691
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6691
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gaugcucaug      360

ugcagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc uggaggggga ggugaacaag aucaagagcg cccuccuguc caccaacaag      480

gccgugguca gccuguccaa cggcgugagc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc aguccugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggggu caccacgccc gugagcaccu acaugcugac caacuccgag      720

cuccugagcc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggcgugaucg acacgcccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggga gcaacaucug ccucacccgc      960

accgaccggg gcugguacug cgacaacgcg ggcuccguga gcuucuuccc gcaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggggccau cguguccugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc gucgacacgg uguccguggg gaacacccug     1320

uacuacguca acaagcagga gggccagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggca aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cguggggcug cuccuguacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6692
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6692
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc cauccccaac      600

cccgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggccagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6693
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6693
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugaccugca gaugcuuaug      360

uguuccacac ccgccaccgg gucuggaucg gcuauagcau caggcguggc cgucugcaag      420

gugcugcacu uggaggguga gguuaacaaa aucaagagcg cucuccugag uacgaauaaa      480

gccguggucu cccugucuaa cggggugagc guacucacuu uuaagguuuu agaucugaag      540

aauuacauug acaaacagcu uuugccuauc cugaacaagc aauccuguuc aauuccaaau      600

ccggaaaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau cacacgggag      660

uuuaguguca acgcgggagu gacuaccccc gugagcacau auaugcugac caauucugag      720

cuucuguccu ugauaaacga uaugccuauu acgaacgacc agaagaaacu caugucaaau      780

aacguccaaa ucguucgcca gcagagcuac aguauuaugu gcaucaucaa ggaagaggug      840

cuggcauaug uagugcaguu accacuguac ggcgucauug auacucccug uuggaaacuc      900

cauacaucuc cucuuugcac cacuaauaca aaggaaggcu ccaacauaug ucugacccga      960

acggaccgug ggugguacug cgauaaugcc ggaagcgugu cguucuuucc acaagcugag     1020

accuguaagg uuugcucuaa cagaguguuc ugcgacacaa ugaacuccuu gacucuaccc     1080

ucagaaguca aucuguguaa uguggauauc uuuaacccua aauaugacug caagauuaug     1140

accaguaaaa cagauguaag cuccucuguu aucacuagcc ucggugccau agugucaugu     1200

uacggcaaga ccaaaugcac agcaaguaau aagaacaagg ggauuaucaa aaccuucucc     1260

aauggaugug acuaugucag caacaagggc guggacacug ucucuguggg uaauacgcug     1320

uacuauguua acaaacagga ggggcaguca cuuuacguga agggagagcc aaucauuaac     1380

uuuuaugauc cgcugguauu ccccagugac gaauuugaug cuagcaucuc ccaagucaau     1440

gagaaaauua accagucuuu ggccuucaua aggaagucgg acgaacuccu gcacaaugug     1500

aacgcgggca agagcacaac caauaucaug auuacuacca ucaucauugu uauaaucgug     1560

auuuuacugu cccuaaucgc cgucggccuc cugcuuuacu gcaaagcacg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6694
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6694
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag cauccccaac      600

cccgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggccagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6695
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6695
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagaau aaaugcaacg ggaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggaccucca gaugcugaug      360

uguagcaccc ccgccacagg auccggcucu gcuauugcca gcggggucgc ggugugcaag      420

guucugcacc ucgagggaga ggugaacaaa aucaaguccg cccugcuuag caccaauaaa      480

gcugucgugu cucuguccaa cggcguuagc gugcucacau uuaagguccu ggaucuuaag      540

aauuacauug acaaacagcu gcucccuauc cugaacaagc aaucuuguuc cauuccgaau      600

cccgaaaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau cacgcgcgag      660

uuuagcguga acgccggcgu cacaaccccu guuucuacau auaugcugac caauuccgag      720

cuucugagcc ucauuaacga uaugcccauc accaacgacc agaagaaacu gauguccaau      780

aacgugcaaa ucgugagaca gcagucuuac agcauuaugu gcaucauuaa ggaagagguc      840

cuugcuuaug ugguucagcu gccucucuac ggggugaucg auacacccug uuggaaacug      900

cauacguccc cucugugcac cacaaauacc aaggaaggaa gcaacauuug ucucacacgg      960

accgaccgcg gcugguacug cgauaaugcc gggucugucu ccuucuuucc gcaagcggag     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgacacaa ugaacucucu gacccuuccc     1080

agcgaaguga aucuguguaa ugucgauauc uuuaacccua aauaugacug caagaucaug     1140

accuccaaaa cagauguguc uagcuccguc auuaccagcc ucggagccau cgugucuugu     1200

uacggcaaga caaaaugcac ggcuuccaau aagaacaagg ggauuaucaa aaccuucagc     1260

aauggaugug acuauguuuc uaacaagggc guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga ggggcagagc cuuuacguga agggagagcc cauuaucaac     1380

uuuuaugauc cucuggucuu ccccuccgac gaauuugaug ccucuaucag ccaagugaau     1440

gagaaaauua accagucccu cgcuuucauc cggaagucug acgaacugcu gcacaaugug     1500

aacgccggca agagcacaac caauauuaug aucacgacca uuaucauugu uaucaucguc     1560

auucuccugu cccuuaucgc cguggggcug cuccuguacu gcaaagcucg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6696
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6696
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauuaaaa gcaaacgcaa uaacaacgau auuaacagcu      120

guaacauucu gcuuugcauc aggccaaaau aucaccgaag aauuuuauca aagcacaugc      180

ucugcaguau ccaaaggaua cuuaggagca uuaagaacag gcugguacac auccguaaua      240

acaauagaac uaucaaacau caaagaaaac aaaugcaacg gcacagacgc caaaguaaaa      300

cucauaaaac aagaacuaga caaauauaaa aacgcaguaa cagaucuaca aaugcucaug      360

ugcuccacac cagcaaccgg aucugguuca gccauagcau ccggcguagc cgucugcaaa      420

guauuacacc ucgaaggaga aguaaacaaa auaaaaucug cccuauuauc uacaaauaaa      480

gccguaguaa gucuaaguaa cggaguauca guacuaacau uuaaaguccu agaccugaaa      540

aacuauaucg acaaacaacu auuaccaaua cuaaacaaac aauccuguuc caucccuaac      600

ccagaaacag uuauggaauu ucaacaaaaa aauaaccgcc uuuuagaaau aacuagagaa      660

uuuucaguaa acgcaggagu uacaacacca guaucaacau acaugcuaac aaauucagaa      720

uuauuauccc uuauaaauga caugccuauc acaaacgauc aaaaaaaauu aauguccaac      780

aacguacaaa uaguaagaca acaaucauau uccaucaugu gcaucauaaa agaagaaguc      840

cucgcauacg uagugcaacu accacuauac ggagucauag auacacccug uuggaaacuu      900

cacacaucuc cacuaugcac aacaaacacg aaagaaggau ccaacauaug ccuaacacga      960

acagacagag gaugguauug cgacaacgcu ggaaguguga gcuucuuccc ucaagcagaa     1020

acuugcaaag uaugcagcaa ucguguauuc ugcgacacaa ugaacucauu aacacuccca     1080

agcgaaguaa accucugcaa uguagacauc uuuaauccaa aauacgauug uaaaauaaug     1140

acuucaaaaa cagacgucuc aucaucugua auaacaucuu uaggagcaau aguuucuugc     1200

uacgguaaaa caaaaugcac cgcauccaac aaaaacaaag gaauaauaaa aacauucucu     1260

aacggcugcg auuacguauc uaacaaagga guugacacag ucucaguagg aaacacacua     1320

uacuacguaa acaaacaaga aggacaaagc cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cauuaguauu uccaagcgau gaauuugacg cuucaauauc acaagucaau     1440

gaaaaaauaa aucagagcuu agcauucaua agaaaaucug augaacuacu acacaaugua     1500

aaugcaggaa aauccacuac caacauaaug auuaccacaa uuauaauagu uaucauagua     1560

auacuauuau cacuaauagc cguuggauua cuacuauacu gcaaagcaag auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6697
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6697
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauccuaaaa gcaaacgcca ucaccaccau acuaaccgcc      120

gucaccuucu gcuucgccuc gggacaaaac aucaccgaag aguucuacca gucaacgugc      180

uccgccgucu caaaaggcua ccuaggcgcc cuccgcaccg ggugguauac cuccgucaua      240

acuaucgaac ucucuaacau caaagaaaac aaauguaacg gcaccgacgc caaagucaaa      300

cuaaucaaac aagaacugga caaauacaaa aacgccguca ccgaccuaca aaugcucaug      360

ugcuccacuc cagccaccgg cuccgguagc gcaaucgccu caggcguagc uguaugcaaa      420

guccuccacc uagaaggcga aguaaacaaa auaaaauccg cccuccucuc aaccaacaag      480

gccgucgucu cacucucaaa cggcgucucc guacucaccu uuaaaguccu agaccuuaaa      540

aacuacaucg acaaacaacu gcuaccaauc cucaacaaac aaucaugcag caucccaaac      600

ccggaaacag ucauggaguu ccaacagaaa aacaaccgac uccucgaaau cacccgcgag      660

uucuccguca acgccggagu caccacaccu guaagcacau acaugcuuac uaauuccgaa      720

cuccuuucac uaauaaacga caugccaaua accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguacgcca acaauccuac uccaucaugu gcaucaucaa agaagaaguc      840

cuggccuaug ucguacaacu cccccuuuac ggugucaucg acacacccug cuggaaacua      900

cacaccagcc cccucugcac aacaaacacc aaagaaggcu ccaacaucug ccucacccgu      960

accgaccgag gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaagccgaa     1020

accugcaaag ucugcagcaa ccgcgucuuc ugcgauacca ugaacucccu cacacuccca     1080

ucugaaguca accucugcaa cgucgauauu uucaauccaa aauacgacug caaaaucaug     1140

acuagcaaaa ccgacguuag cuccuccguc aucaccuccc ucggcgccau aguuucaugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aaccuucucc     1260

aacgggugcg acuacguauc uaauaaagga gucgacaccg ucucaguagg aaacacccuc     1320

uacuauguca acaaacaaga aggccaauca cuauacguua aaggcgaacc aaucaucaac     1380

uucuacgacc cacucgucuu ccccagcgac gaguuugacg ccucaaucuc gcaagucaau     1440

gaaaagauua accaaucccu agccuucauc cgaaaaagug acgaacuccu ccacaacguu     1500

aacgccggca aaucuacaac caacaucaug aucaccacua uaaucaucgu caucauaguc     1560

auacuucuca gccucaucgc agucggacuc cuccuuuauu gcaaggcacg auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6698
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6698
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6699
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6699
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6700
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6700
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6701
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6701
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6702
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6702
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6703
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6703
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6704
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6704
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auuaaaagca      120

aacgcaauaa caacgauauu aacagcugua acauucugcu uugcaucagg ccaaaauauc      180

accgaagaau uuuaucaaag cacaugcucu gcaguaucca aaggauacuu aggagcauua      240

agaacaggcu gguacacauc cguaauaaca auagaacuau caaacaucaa agaaaacaaa      300

ugcaacggca cagacgccaa aguaaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacag aucuacaaau gcucaugugc uccacaccag caaccggauc ugguucagcc      420

auagcauccg gcguagccgu cugcaaagua uuacaccucg aaggagaagu aaacaaaaua      480

aaaucugccc uauuaucuac aaauaaagcc guaguaaguc uaaguaacgg aguaucagua      540

cuaacauuua aaguccuaga ccugaaaaac uauaucgaca aacaacuauu accaauacua      600

aacaaacaau ccuguuccau cccuaaccca gaaacaguua uggaauuuca acaaaaaaau      660

aaccgccuuu uagaaauaac uagagaauuu ucaguaaacg caggaguuac aacaccagua      720

ucaacauaca ugcuaacaaa uucagaauua uuaucccuua uaaaugacau gccuaucaca      780

aacgaucaaa aaaaauuaau guccaacaac guacaaauag uaagacaaca aucauauucc      840

aucaugugca ucauaaaaga agaaguccuc gcauacguag ugcaacuacc acuauacgga      900

gucauagaua cacccuguug gaaacuucac acaucuccac uaugcacaac aaacacgaaa      960

gaaggaucca acauaugccu aacacgaaca gacagaggau gguauugcga caacgcugga     1020

agugugagcu ucuucccuca agcagaaacu ugcaaaguau gcagcaaucg uguauucugc     1080

gacacaauga acucauuaac acucccaagc gaaguaaacc ucugcaaugu agacaucuuu     1140

aauccaaaau acgauuguaa aauaaugacu ucaaaaacag acgucucauc aucuguaaua     1200

acaucuuuag gagcaauagu uucuugcuac gguaaaacaa aaugcaccgc auccaacaaa     1260

aacaaaggaa uaauaaaaac auucucuaac ggcugcgauu acguaucuaa caaaggaguu     1320

gacacagucu caguaggaaa cacacuauac uacguaaaca aacaagaagg acaaagccua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccau uaguauuucc aagcgaugaa     1440

uuugacgcuu caauaucaca agucaaugaa aaaauaaauc agagcuuagc auucauaaga     1500

aaaucugaug aacuacuaca caauguaaau gcaggaaaau ccacuaccaa cauaaugauu     1560

accacaauua uaauaguuau cauaguaaua cuauuaucac uaauagccgu uggauuacua     1620

cuauacugca aagcaagaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6705
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6705
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagca      120

aacgccauca ccaccauacu aaccgccguc accuucugcu ucgccucggg acaaaacauc      180

accgaagagu ucuaccaguc aacgugcucc gccgucucaa aaggcuaccu aggcgcccuc      240

cgcaccgggu gguauaccuc cgucauaacu aucgaacucu cuaacaucaa agaaaacaaa      300

uguaacggca ccgacgccaa agucaaacua aucaaacaag aacuggacaa auacaaaaac      360

gccgucaccg accuacaaau gcucaugugc uccacuccag ccaccggcuc cgguagcgca      420

aucgccucag gcguagcugu augcaaaguc cuccaccuag aaggcgaagu aaacaaaaua      480

aaauccgccc uccucucaac caacaaggcc gucgucucac ucucaaacgg cgucuccgua      540

cucaccuuua aaguccuaga ccuuaaaaac uacaucgaca aacaacugcu accaauccuc      600

aacaaacaau caugcagcau cccaaacccg gaaacaguca uggaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg ccggagucac cacaccugua      720

agcacauaca ugcuuacuaa uuccgaacuc cuuucacuaa uaaacgacau gccaauaacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uacgccaaca auccuacucc      840

aucaugugca ucaucaaaga agaaguccug gccuaugucg uacaacuccc ccuuuacggu      900

gucaucgaca cacccugcug gaaacuacac accagccccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccguacc gaccgaggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacc ugcaaagucu gcagcaaccg cgucuucugc     1080

gauaccauga acucccucac acucccaucu gaagucaacc ucugcaacgu cgauauuuuc     1140

aauccaaaau acgacugcaa aaucaugacu agcaaaaccg acguuagcuc cuccgucauc     1200

accucccucg gcgccauagu uucaugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac cuucuccaac gggugcgacu acguaucuaa uaaaggaguc     1320

gacaccgucu caguaggaaa cacccucuac uaugucaaca aacaagaagg ccaaucacua     1380

uacguuaaag gcgaaccaau caucaacuuc uacgacccac ucgucuuccc cagcgacgag     1440

uuugacgccu caaucucgca agucaaugaa aagauuaacc aaucccuagc cuucauccga     1500

aaaagugacg aacuccucca caacguuaac gccggcaaau cuacaaccaa caucaugauc     1560

accacuauaa ucaucgucau cauagucaua cuucucagcc ucaucgcagu cggacuccuc     1620

cuuuauugca aggcacgaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  6706
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6706
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau ccccaacccc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6707
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6707
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagau gcucaugugc agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccugg agggggaggu gaacaagauc      480

aagagcgccc uccuguccac caacaaggcc guggucagcc uguccaacgg cgugagcgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcagu ccugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggggucac cacgcccgug      720

agcaccuaca ugcugaccaa cuccgagcuc cugagccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggc      900

gugaucgaca cgcccugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gaggggagca acaucugccu cacccgcacc gaccggggcu gguacugcga caacgcgggc     1020

uccgugagcu ucuucccgca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gggccaucgu guccugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcguc     1320

gacacggugu ccguggggaa cacccuguac uacgucaaca agcaggaggg ccagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccggcaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu ggggcugcuc     1620

cuguacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6708
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6708
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau ccccaacccc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg ccagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6709
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6709
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug accugcagau gcuuaugugu uccacacccg ccaccggguc uggaucggcu      420

auagcaucag gcguggccgu cugcaaggug cugcacuugg agggugaggu uaacaaaauc      480

aagagcgcuc uccugaguac gaauaaagcc guggucuccc ugucuaacgg ggugagcgua      540

cucacuuuua agguuuuaga ucugaagaau uacauugaca aacagcuuuu gccuauccug      600

aacaagcaau ccuguucaau uccaaauccg gaaaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaaucac acgggaguuu agugucaacg cgggagugac uacccccgug      720

agcacauaua ugcugaccaa uucugagcuu cuguccuuga uaaacgauau gccuauuacg      780

aacgaccaga agaaacucau gucaaauaac guccaaaucg uucgccagca gagcuacagu      840

auuaugugca ucaucaagga agaggugcug gcauauguag ugcaguuacc acuguacggc      900

gucauugaua cucccuguug gaaacuccau acaucuccuc uuugcaccac uaauacaaag      960

gaaggcucca acauaugucu gacccgaacg gaccgugggu gguacugcga uaaugccgga     1020

agcgugucgu ucuuuccaca agcugagacc uguaagguuu gcucuaacag aguguucugc     1080

gacacaauga acuccuugac ucuacccuca gaagucaauc uguguaaugu ggauaucuuu     1140

aacccuaaau augacugcaa gauuaugacc aguaaaacag auguaagcuc cucuguuauc     1200

acuagccucg gugccauagu gucauguuac ggcaagacca aaugcacagc aaguaauaag     1260

aacaagggga uuaucaaaac cuucuccaau ggaugugacu augucagcaa caagggcgug     1320

gacacugucu cuguggguaa uacgcuguac uauguuaaca aacaggaggg gcagucacuu     1380

uacgugaagg gagagccaau cauuaacuuu uaugauccgc ugguauuccc cagugacgaa     1440

uuugaugcua gcaucuccca agucaaugag aaaauuaacc agucuuuggc cuucauaagg     1500

aagucggacg aacuccugca caaugugaac gcgggcaaga gcacaaccaa uaucaugauu     1560

acuaccauca ucauuguuau aaucgugauu uuacuguccc uaaucgccgu cggccuccug     1620

cuuuacugca aagcacggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6710
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6710
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau ccccaacccc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg ccagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6711
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6711
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaauaaa      300

ugcaacggga ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg accuccagau gcugaugugu agcacccccg ccacaggauc cggcucugcu      420

auugccagcg gggucgcggu gugcaagguu cugcaccucg agggagaggu gaacaaaauc      480

aaguccgccc ugcuuagcac caauaaagcu gucgugucuc uguccaacgg cguuagcgug      540

cucacauuua agguccugga ucuuaagaau uacauugaca aacagcugcu cccuauccug      600

aacaagcaau cuuguuccau uccgaauccc gaaaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaaucac gcgcgaguuu agcgugaacg ccggcgucac aaccccuguu      720

ucuacauaua ugcugaccaa uuccgagcuu cugagccuca uuaacgauau gcccaucacc      780

aacgaccaga agaaacugau guccaauaac gugcaaaucg ugagacagca gucuuacagc      840

auuaugugca ucauuaagga agagguccuu gcuuaugugg uucagcugcc ucucuacggg      900

gugaucgaua cacccuguug gaaacugcau acguccccuc ugugcaccac aaauaccaag      960

gaaggaagca acauuugucu cacacggacc gaccgcggcu gguacugcga uaaugccggg     1020

ucugucuccu ucuuuccgca agcggagacg uguaaggugu gcagcaacag aguuuucugc     1080

gacacaauga acucucugac ccuucccagc gaagugaauc uguguaaugu cgauaucuuu     1140

aacccuaaau augacugcaa gaucaugacc uccaaaacag augugucuag cuccgucauu     1200

accagccucg gagccaucgu gucuuguuac ggcaagacaa aaugcacggc uuccaauaag     1260

aacaagggga uuaucaaaac cuucagcaau ggaugugacu auguuucuaa caagggcgug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg gcagagccuu     1380

uacgugaagg gagagcccau uaucaacuuu uaugauccuc uggucuuccc cuccgacgaa     1440

uuugaugccu cuaucagcca agugaaugag aaaauuaacc agucccucgc uuucauccgg     1500

aagucugacg aacugcugca caaugugaac gccggcaaga gcacaaccaa uauuaugauc     1560

acgaccauua ucauuguuau caucgucauu cuccuguccc uuaucgccgu ggggcugcuc     1620

cuguacugca aagcucgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6712
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6712
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auuaaaagca      120

aacgcaauaa caacgauauu aacagcugua acauucugcu uugcaucagg ccaaaauauc      180

accgaagaau uuuaucaaag cacaugcucu gcaguaucca aaggauacuu aggagcauua      240

agaacaggcu gguacacauc cguaauaaca auagaacuau caaacaucaa agaaaacaaa      300

ugcaacggca cagacgccaa aguaaaacuc auaaaacaag aacuagacaa auauaaaaac      360

gcaguaacag aucuacaaau gcucaugugc uccacaccag caaccggauc ugguucagcc      420

auagcauccg gcguagccgu cugcaaagua uuacaccucg aaggagaagu aaacaaaaua      480

aaaucugccc uauuaucuac aaauaaagcc guaguaaguc uaaguaacgg aguaucagua      540

cuaacauuua aaguccuaga ccugaaaaac uauaucgaca aacaacuauu accaauacua      600

aacaaacaau ccuguuccau cccuaaccca gaaacaguua uggaauuuca acaaaaaaau      660

aaccgccuuu uagaaauaac uagagaauuu ucaguaaacg caggaguuac aacaccagua      720

ucaacauaca ugcuaacaaa uucagaauua uuaucccuua uaaaugacau gccuaucaca      780

aacgaucaaa aaaaauuaau guccaacaac guacaaauag uaagacaaca aucauauucc      840

aucaugugca ucauaaaaga agaaguccuc gcauacguag ugcaacuacc acuauacgga      900

gucauagaua cacccuguug gaaacuucac acaucuccac uaugcacaac aaacacgaaa      960

gaaggaucca acauaugccu aacacgaaca gacagaggau gguauugcga caacgcugga     1020

agugugagcu ucuucccuca agcagaaacu ugcaaaguau gcagcaaucg uguauucugc     1080

gacacaauga acucauuaac acucccaagc gaaguaaacc ucugcaaugu agacaucuuu     1140

aauccaaaau acgauuguaa aauaaugacu ucaaaaacag acgucucauc aucuguaaua     1200

acaucuuuag gagcaauagu uucuugcuac gguaaaacaa aaugcaccgc auccaacaaa     1260

aacaaaggaa uaauaaaaac auucucuaac ggcugcgauu acguaucuaa caaaggaguu     1320

gacacagucu caguaggaaa cacacuauac uacguaaaca aacaagaagg acaaagccua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccau uaguauuucc aagcgaugaa     1440

uuugacgcuu caauaucaca agucaaugaa aaaauaaauc agagcuuagc auucauaaga     1500

aaaucugaug aacuacuaca caauguaaau gcaggaaaau ccacuaccaa cauaaugauu     1560

accacaauua uaauaguuau cauaguaaua cuauuaucac uaauagccgu uggauuacua     1620

cuauacugca aagcaagaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6713
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6713
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau ccuaaaagca      120

aacgccauca ccaccauacu aaccgccguc accuucugcu ucgccucggg acaaaacauc      180

accgaagagu ucuaccaguc aacgugcucc gccgucucaa aaggcuaccu aggcgcccuc      240

cgcaccgggu gguauaccuc cgucauaacu aucgaacucu cuaacaucaa agaaaacaaa      300

uguaacggca ccgacgccaa agucaaacua aucaaacaag aacuggacaa auacaaaaac      360

gccgucaccg accuacaaau gcucaugugc uccacuccag ccaccggcuc cgguagcgca      420

aucgccucag gcguagcugu augcaaaguc cuccaccuag aaggcgaagu aaacaaaaua      480

aaauccgccc uccucucaac caacaaggcc gucgucucac ucucaaacgg cgucuccgua      540

cucaccuuua aaguccuaga ccuuaaaaac uacaucgaca aacaacugcu accaauccuc      600

aacaaacaau caugcagcau cccaaacccg gaaacaguca uggaguucca acagaaaaac      660

aaccgacucc ucgaaaucac ccgcgaguuc uccgucaacg ccggagucac cacaccugua      720

agcacauaca ugcuuacuaa uuccgaacuc cuuucacuaa uaaacgacau gccaauaacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uacgccaaca auccuacucc      840

aucaugugca ucaucaaaga agaaguccug gccuaugucg uacaacuccc ccuuuacggu      900

gucaucgaca cacccugcug gaaacuacac accagccccc ucugcacaac aaacaccaaa      960

gaaggcucca acaucugccu cacccguacc gaccgaggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca agccgaaacc ugcaaagucu gcagcaaccg cgucuucugc     1080

gauaccauga acucccucac acucccaucu gaagucaacc ucugcaacgu cgauauuuuc     1140

aauccaaaau acgacugcaa aaucaugacu agcaaaaccg acguuagcuc cuccgucauc     1200

accucccucg gcgccauagu uucaugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac cuucuccaac gggugcgacu acguaucuaa uaaaggaguc     1320

gacaccgucu caguaggaaa cacccucuac uaugucaaca aacaagaagg ccaaucacua     1380

uacguuaaag gcgaaccaau caucaacuuc uacgacccac ucgucuuccc cagcgacgag     1440

uuugacgccu caaucucgca agucaaugaa aagauuaacc aaucccuagc cuucauccga     1500

aaaagugacg aacuccucca caacguuaac gccggcaaau cuacaaccaa caucaugauc     1560

accacuauaa ucaucgucau cauagucaua cuucucagcc ucaucgcagu cggacuccuc     1620

cuuuauugca aggcacgaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  6714
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6714
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6715
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6715
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccuggagg gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug      540

gucagccugu ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug      780

agccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac     1020

cggggcuggu acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac     1380

gucaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

ggcaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg gcugcuccug uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6716
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6716
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6717
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6717
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc      420

acacccgcca ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug      480

cacuuggagg gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug      540

gucucccugu cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac      600

auugacaaac agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu      720

gucaacgcgg gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug      780

uccuugauaa acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc      840

caaaucguuc gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca      900

uauguagugc aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca      960

ucuccucuuu gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac     1020

cguggguggu acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu     1080

aagguuugcu cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa     1140

gucaaucugu guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu     1200

aaaacagaug uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc     1260

aagaccaaau gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga     1320

ugugacuaug ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau     1380

guuaacaaac aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau     1440

gauccgcugg uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa     1500

auuaaccagu cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg     1560

ggcaagagca caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua     1620

cugucccuaa ucgccgucgg ccuccugcuu uacugcaaag cacggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6718
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6718
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6719
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6719
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc      420

acccccgcca caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug      480

caccucgagg gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc      540

gugucucugu ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac      600

auugacaaac agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc      720

gugaacgccg gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug      780

agccucauua acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug      840

caaaucguga gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu      900

uaugugguuc agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg      960

uccccucugu gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac     1020

cgcggcuggu acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu     1080

aaggugugca gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa     1140

gugaaucugu guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc     1200

aaaacagaug ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc     1260

aagacaaaau gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga     1320

ugugacuaug uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau     1440

gauccucugg ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa     1500

auuaaccagu cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc     1560

ggcaagagca caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc     1620

cugucccuua ucgccguggg gcugcuccug uacugcaaag cucgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6720
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6720
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu aaaagcaaac gcaauaacaa cgauauuaac agcuguaaca      180

uucugcuuug caucaggcca aaauaucacc gaagaauuuu aucaaagcac augcucugca      240

guauccaaag gauacuuagg agcauuaaga acaggcuggu acacauccgu aauaacaaua      300

gaacuaucaa acaucaaaga aaacaaaugc aacggcacag acgccaaagu aaaacucaua      360

aaacaagaac uagacaaaua uaaaaacgca guaacagauc uacaaaugcu caugugcucc      420

acaccagcaa ccggaucugg uucagccaua gcauccggcg uagccgucug caaaguauua      480

caccucgaag gagaaguaaa caaaauaaaa ucugcccuau uaucuacaaa uaaagccgua      540

guaagucuaa guaacggagu aucaguacua acauuuaaag uccuagaccu gaaaaacuau      600

aucgacaaac aacuauuacc aauacuaaac aaacaauccu guuccauccc uaacccagaa      660

acaguuaugg aauuucaaca aaaaaauaac cgccuuuuag aaauaacuag agaauuuuca      720

guaaacgcag gaguuacaac accaguauca acauacaugc uaacaaauuc agaauuauua      780

ucccuuauaa augacaugcc uaucacaaac gaucaaaaaa aauuaauguc caacaacgua      840

caaauaguaa gacaacaauc auauuccauc augugcauca uaaaagaaga aguccucgca      900

uacguagugc aacuaccacu auacggaguc auagauacac ccuguuggaa acuucacaca      960

ucuccacuau gcacaacaaa cacgaaagaa ggauccaaca uaugccuaac acgaacagac     1020

agaggauggu auugcgacaa cgcuggaagu gugagcuucu ucccucaagc agaaacuugc     1080

aaaguaugca gcaaucgugu auucugcgac acaaugaacu cauuaacacu cccaagcgaa     1140

guaaaccucu gcaauguaga caucuuuaau ccaaaauacg auuguaaaau aaugacuuca     1200

aaaacagacg ucucaucauc uguaauaaca ucuuuaggag caauaguuuc uugcuacggu     1260

aaaacaaaau gcaccgcauc caacaaaaac aaaggaauaa uaaaaacauu cucuaacggc     1320

ugcgauuacg uaucuaacaa aggaguugac acagucucag uaggaaacac acuauacuac     1380

guaaacaaac aagaaggaca aagccuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccauuag uauuuccaag cgaugaauuu gacgcuucaa uaucacaagu caaugaaaaa     1500

auaaaucaga gcuuagcauu cauaagaaaa ucugaugaac uacuacacaa uguaaaugca     1560

ggaaaaucca cuaccaacau aaugauuacc acaauuauaa uaguuaucau aguaauacua     1620

uuaucacuaa uagccguugg auuacuacua uacugcaaag caagauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6721
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6721
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauccu aaaagcaaac gccaucacca ccauacuaac cgccgucacc      180

uucugcuucg ccucgggaca aaacaucacc gaagaguucu accagucaac gugcuccgcc      240

gucucaaaag gcuaccuagg cgcccuccgc accggguggu auaccuccgu cauaacuauc      300

gaacucucua acaucaaaga aaacaaaugu aacggcaccg acgccaaagu caaacuaauc      360

aaacaagaac uggacaaaua caaaaacgcc gucaccgacc uacaaaugcu caugugcucc      420

acuccagcca ccggcuccgg uagcgcaauc gccucaggcg uagcuguaug caaaguccuc      480

caccuagaag gcgaaguaaa caaaauaaaa uccgcccucc ucucaaccaa caaggccguc      540

gucucacucu caaacggcgu cuccguacuc accuuuaaag uccuagaccu uaaaaacuac      600

aucgacaaac aacugcuacc aauccucaac aaacaaucau gcagcauccc aaacccggaa      660

acagucaugg aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc      720

gucaacgccg gagucaccac accuguaagc acauacaugc uuacuaauuc cgaacuccuu      780

ucacuaauaa acgacaugcc aauaaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguac gccaacaauc cuacuccauc augugcauca ucaaagaaga aguccuggcc      900

uaugucguac aacucccccu uuacgguguc aucgacacac ccugcuggaa acuacacacc      960

agcccccucu gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccguaccgac     1020

cgaggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaaccugc     1080

aaagucugca gcaaccgcgu cuucugcgau accaugaacu cccucacacu cccaucugaa     1140

gucaaccucu gcaacgucga uauuuucaau ccaaaauacg acugcaaaau caugacuagc     1200

aaaaccgacg uuagcuccuc cgucaucacc ucccucggcg ccauaguuuc augcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaaccuu cuccaacggg     1320

ugcgacuacg uaucuaauaa aggagucgac accgucucag uaggaaacac ccucuacuau     1380

gucaacaaac aagaaggcca aucacuauac guuaaaggcg aaccaaucau caacuucuac     1440

gacccacucg ucuuccccag cgacgaguuu gacgccucaa ucucgcaagu caaugaaaag     1500

auuaaccaau cccuagccuu cauccgaaaa agugacgaac uccuccacaa cguuaacgcc     1560

ggcaaaucua caaccaacau caugaucacc acuauaauca ucgucaucau agucauacuu     1620

cucagccuca ucgcagucgg acuccuccuu uauugcaagg cacgauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6722
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6722
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6723
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6723
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6724
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6724
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6725
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6725
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6726
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6726
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6727
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6727
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6728
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6728
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauuaaaa      120

gcaaacgcaa uaacaacgau auuaacagcu guaacauucu gcuuugcauc aggccaaaau      180

aucaccgaag aauuuuauca aagcacaugc ucugcaguau ccaaaggaua cuuaggagca      240

uuaagaacag gcugguacac auccguaaua acaauagaac uaucaaacau caaagaaaac      300

aaaugcaacg gcacagacgc caaaguaaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cagaucuaca aaugcucaug ugcuccacac cagcaaccgg aucugguuca      420

gccauagcau ccggcguagc cgucugcaaa guauuacacc ucgaaggaga aguaaacaaa      480

auaaaaucug cccuauuauc uacaaauaaa gccguaguaa gucuaaguaa cggaguauca      540

guacuaacau uuaaaguccu agaccugaaa aacuauaucg acaaacaacu auuaccaaua      600

cuaaacaaac aauccuguuc caucccuaac ccagaaacag uuauggaauu ucaacaaaaa      660

aauaaccgcc uuuuagaaau aacuagagaa uuuucaguaa acgcaggagu uacaacacca      720

guaucaacau acaugcuaac aaauucagaa uuauuauccc uuauaaauga caugccuauc      780

acaaacgauc aaaaaaaauu aauguccaac aacguacaaa uaguaagaca acaaucauau      840

uccaucaugu gcaucauaaa agaagaaguc cucgcauacg uagugcaacu accacuauac      900

ggagucauag auacacccug uuggaaacuu cacacaucuc cacuaugcac aacaaacacg      960

aaagaaggau ccaacauaug ccuaacacga acagacagag gaugguauug cgacaacgcu     1020

ggaaguguga gcuucuuccc ucaagcagaa acuugcaaag uaugcagcaa ucguguauuc     1080

ugcgacacaa ugaacucauu aacacuccca agcgaaguaa accucugcaa uguagacauc     1140

uuuaauccaa aauacgauug uaaaauaaug acuucaaaaa cagacgucuc aucaucugua     1200

auaacaucuu uaggagcaau aguuucuugc uacgguaaaa caaaaugcac cgcauccaac     1260

aaaaacaaag gaauaauaaa aacauucucu aacggcugcg auuacguauc uaacaaagga     1320

guugacacag ucucaguagg aaacacacua uacuacguaa acaaacaaga aggacaaagc     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cauuaguauu uccaagcgau     1440

gaauuugacg cuucaauauc acaagucaau gaaaaaauaa aucagagcuu agcauucaua     1500

agaaaaucug augaacuacu acacaaugua aaugcaggaa aauccacuac caacauaaug     1560

auuaccacaa uuauaauagu uaucauagua auacuauuau cacuaauagc cguuggauua     1620

cuacuauacu gcaaagcaag auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6729
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6729
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gcaaacgcca ucaccaccau acuaaccgcc gucaccuucu gcuucgccuc gggacaaaac      180

aucaccgaag aguucuacca gucaacgugc uccgccgucu caaaaggcua ccuaggcgcc      240

cuccgcaccg ggugguauac cuccgucaua acuaucgaac ucucuaacau caaagaaaac      300

aaauguaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacugga caaauacaaa      360

aacgccguca ccgaccuaca aaugcucaug ugcuccacuc cagccaccgg cuccgguagc      420

gcaaucgccu caggcguagc uguaugcaaa guccuccacc uagaaggcga aguaaacaaa      480

auaaaauccg cccuccucuc aaccaacaag gccgucgucu cacucucaaa cggcgucucc      540

guacucaccu uuaaaguccu agaccuuaaa aacuacaucg acaaacaacu gcuaccaauc      600

cucaacaaac aaucaugcag caucccaaac ccggaaacag ucauggaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgccggagu caccacaccu      720

guaagcacau acaugcuuac uaauuccgaa cuccuuucac uaauaaacga caugccaaua      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguacgcca acaauccuac      840

uccaucaugu gcaucaucaa agaagaaguc cuggccuaug ucguacaacu cccccuuuac      900

ggugucaucg acacacccug cuggaaacua cacaccagcc cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgu accgaccgag gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa accugcaaag ucugcagcaa ccgcgucuuc     1080

ugcgauacca ugaacucccu cacacuccca ucugaaguca accucugcaa cgucgauauu     1140

uucaauccaa aauacgacug caaaaucaug acuagcaaaa ccgacguuag cuccuccguc     1200

aucaccuccc ucggcgccau aguuucaugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aaccuucucc aacgggugcg acuacguauc uaauaaagga     1320

gucgacaccg ucucaguagg aaacacccuc uacuauguca acaaacaaga aggccaauca     1380

cuauacguua aaggcgaacc aaucaucaac uucuacgacc cacucgucuu ccccagcgac     1440

gaguuugacg ccucaaucuc gcaagucaau gaaaagauua accaaucccu agccuucauc     1500

cgaaaaagug acgaacuccu ccacaacguu aacgccggca aaucuacaac caacaucaug     1560

aucaccacua uaaucaucgu caucauaguc auacuucuca gccucaucgc agucggacuc     1620

cuccuuuauu gcaaggcacg auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  6730
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6730
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6731
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6731
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6732
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6732
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6733
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6733
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6734
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6734
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6735
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6735
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6736
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6736
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauuaaaa      120

gcaaacgcaa uaacaacgau auuaacagcu guaacauucu gcuuugcauc aggccaaaau      180

aucaccgaag aauuuuauca aagcacaugc ucugcaguau ccaaaggaua cuuaggagca      240

uuaagaacag gcugguacac auccguaaua acaauagaac uaucaaacau caaagaaaac      300

aaaugcaacg gcacagacgc caaaguaaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cagaucuaca aaugcucaug ugcuccacac cagcaaccgg aucugguuca      420

gccauagcau ccggcguagc cgucugcaaa guauuacacc ucgaaggaga aguaaacaaa      480

auaaaaucug cccuauuauc uacaaauaaa gccguaguaa gucuaaguaa cggaguauca      540

guacuaacau uuaaaguccu agaccugaaa aacuauaucg acaaacaacu auuaccaaua      600

cuaaacaaac aauccuguuc caucccuaac ccagaaacag uuauggaauu ucaacaaaaa      660

aauaaccgcc uuuuagaaau aacuagagaa uuuucaguaa acgcaggagu uacaacacca      720

guaucaacau acaugcuaac aaauucagaa uuauuauccc uuauaaauga caugccuauc      780

acaaacgauc aaaaaaaauu aauguccaac aacguacaaa uaguaagaca acaaucauau      840

uccaucaugu gcaucauaaa agaagaaguc cucgcauacg uagugcaacu accacuauac      900

ggagucauag auacacccug uuggaaacuu cacacaucuc cacuaugcac aacaaacacg      960

aaagaaggau ccaacauaug ccuaacacga acagacagag gaugguauug cgacaacgcu     1020

ggaaguguga gcuucuuccc ucaagcagaa acuugcaaag uaugcagcaa ucguguauuc     1080

ugcgacacaa ugaacucauu aacacuccca agcgaaguaa accucugcaa uguagacauc     1140

uuuaauccaa aauacgauug uaaaauaaug acuucaaaaa cagacgucuc aucaucugua     1200

auaacaucuu uaggagcaau aguuucuugc uacgguaaaa caaaaugcac cgcauccaac     1260

aaaaacaaag gaauaauaaa aacauucucu aacggcugcg auuacguauc uaacaaagga     1320

guugacacag ucucaguagg aaacacacua uacuacguaa acaaacaaga aggacaaagc     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cauuaguauu uccaagcgau     1440

gaauuugacg cuucaauauc acaagucaau gaaaaaauaa aucagagcuu agcauucaua     1500

agaaaaucug augaacuacu acacaaugua aaugcaggaa aauccacuac caacauaaug     1560

auuaccacaa uuauaauagu uaucauagua auacuauuau cacuaauagc cguuggauua     1620

cuacuauacu gcaaagcaag auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6737
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6737
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gcaaacgcca ucaccaccau acuaaccgcc gucaccuucu gcuucgccuc gggacaaaac      180

aucaccgaag aguucuacca gucaacgugc uccgccgucu caaaaggcua ccuaggcgcc      240

cuccgcaccg ggugguauac cuccgucaua acuaucgaac ucucuaacau caaagaaaac      300

aaauguaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacugga caaauacaaa      360

aacgccguca ccgaccuaca aaugcucaug ugcuccacuc cagccaccgg cuccgguagc      420

gcaaucgccu caggcguagc uguaugcaaa guccuccacc uagaaggcga aguaaacaaa      480

auaaaauccg cccuccucuc aaccaacaag gccgucgucu cacucucaaa cggcgucucc      540

guacucaccu uuaaaguccu agaccuuaaa aacuacaucg acaaacaacu gcuaccaauc      600

cucaacaaac aaucaugcag caucccaaac ccggaaacag ucauggaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgccggagu caccacaccu      720

guaagcacau acaugcuuac uaauuccgaa cuccuuucac uaauaaacga caugccaaua      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguacgcca acaauccuac      840

uccaucaugu gcaucaucaa agaagaaguc cuggccuaug ucguacaacu cccccuuuac      900

ggugucaucg acacacccug cuggaaacua cacaccagcc cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgu accgaccgag gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa accugcaaag ucugcagcaa ccgcgucuuc     1080

ugcgauacca ugaacucccu cacacuccca ucugaaguca accucugcaa cgucgauauu     1140

uucaauccaa aauacgacug caaaaucaug acuagcaaaa ccgacguuag cuccuccguc     1200

aucaccuccc ucggcgccau aguuucaugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aaccuucucc aacgggugcg acuacguauc uaauaaagga     1320

gucgacaccg ucucaguagg aaacacccuc uacuauguca acaaacaaga aggccaauca     1380

cuauacguua aaggcgaacc aaucaucaac uucuacgacc cacucgucuu ccccagcgac     1440

gaguuugacg ccucaaucuc gcaagucaau gaaaagauua accaaucccu agccuucauc     1500

cgaaaaagug acgaacuccu ccacaacguu aacgccggca aaucuacaac caacaucaug     1560

aucaccacua uaaucaucgu caucauaguc auacuucuca gccucaucgc agucggacuc     1620

cuccuuuauu gcaaggcacg auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  6738
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6738
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6739
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6739
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6740
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6740
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6741
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6741
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6742
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6742
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6743
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6743
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6744
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6744
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauuaaaa      120

gcaaacgcaa uaacaacgau auuaacagcu guaacauucu gcuuugcauc aggccaaaau      180

aucaccgaag aauuuuauca aagcacaugc ucugcaguau ccaaaggaua cuuaggagca      240

uuaagaacag gcugguacac auccguaaua acaauagaac uaucaaacau caaagaaaac      300

aaaugcaacg gcacagacgc caaaguaaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cagaucuaca aaugcucaug ugcuccacac cagcaaccgg aucugguuca      420

gccauagcau ccggcguagc cgucugcaaa guauuacacc ucgaaggaga aguaaacaaa      480

auaaaaucug cccuauuauc uacaaauaaa gccguaguaa gucuaaguaa cggaguauca      540

guacuaacau uuaaaguccu agaccugaaa aacuauaucg acaaacaacu auuaccaaua      600

cuaaacaaac aauccuguuc caucccuaac ccagaaacag uuauggaauu ucaacaaaaa      660

aauaaccgcc uuuuagaaau aacuagagaa uuuucaguaa acgcaggagu uacaacacca      720

guaucaacau acaugcuaac aaauucagaa uuauuauccc uuauaaauga caugccuauc      780

acaaacgauc aaaaaaaauu aauguccaac aacguacaaa uaguaagaca acaaucauau      840

uccaucaugu gcaucauaaa agaagaaguc cucgcauacg uagugcaacu accacuauac      900

ggagucauag auacacccug uuggaaacuu cacacaucuc cacuaugcac aacaaacacg      960

aaagaaggau ccaacauaug ccuaacacga acagacagag gaugguauug cgacaacgcu     1020

ggaaguguga gcuucuuccc ucaagcagaa acuugcaaag uaugcagcaa ucguguauuc     1080

ugcgacacaa ugaacucauu aacacuccca agcgaaguaa accucugcaa uguagacauc     1140

uuuaauccaa aauacgauug uaaaauaaug acuucaaaaa cagacgucuc aucaucugua     1200

auaacaucuu uaggagcaau aguuucuugc uacgguaaaa caaaaugcac cgcauccaac     1260

aaaaacaaag gaauaauaaa aacauucucu aacggcugcg auuacguauc uaacaaagga     1320

guugacacag ucucaguagg aaacacacua uacuacguaa acaaacaaga aggacaaagc     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cauuaguauu uccaagcgau     1440

gaauuugacg cuucaauauc acaagucaau gaaaaaauaa aucagagcuu agcauucaua     1500

agaaaaucug augaacuacu acacaaugua aaugcaggaa aauccacuac caacauaaug     1560

auuaccacaa uuauaauagu uaucauagua auacuauuau cacuaauagc cguuggauua     1620

cuacuauacu gcaaagcaag auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6745
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6745
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gcaaacgcca ucaccaccau acuaaccgcc gucaccuucu gcuucgccuc gggacaaaac      180

aucaccgaag aguucuacca gucaacgugc uccgccgucu caaaaggcua ccuaggcgcc      240

cuccgcaccg ggugguauac cuccgucaua acuaucgaac ucucuaacau caaagaaaac      300

aaauguaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacugga caaauacaaa      360

aacgccguca ccgaccuaca aaugcucaug ugcuccacuc cagccaccgg cuccgguagc      420

gcaaucgccu caggcguagc uguaugcaaa guccuccacc uagaaggcga aguaaacaaa      480

auaaaauccg cccuccucuc aaccaacaag gccgucgucu cacucucaaa cggcgucucc      540

guacucaccu uuaaaguccu agaccuuaaa aacuacaucg acaaacaacu gcuaccaauc      600

cucaacaaac aaucaugcag caucccaaac ccggaaacag ucauggaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgccggagu caccacaccu      720

guaagcacau acaugcuuac uaauuccgaa cuccuuucac uaauaaacga caugccaaua      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguacgcca acaauccuac      840

uccaucaugu gcaucaucaa agaagaaguc cuggccuaug ucguacaacu cccccuuuac      900

ggugucaucg acacacccug cuggaaacua cacaccagcc cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgu accgaccgag gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa accugcaaag ucugcagcaa ccgcgucuuc     1080

ugcgauacca ugaacucccu cacacuccca ucugaaguca accucugcaa cgucgauauu     1140

uucaauccaa aauacgacug caaaaucaug acuagcaaaa ccgacguuag cuccuccguc     1200

aucaccuccc ucggcgccau aguuucaugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aaccuucucc aacgggugcg acuacguauc uaauaaagga     1320

gucgacaccg ucucaguagg aaacacccuc uacuauguca acaaacaaga aggccaauca     1380

cuauacguua aaggcgaacc aaucaucaac uucuacgacc cacucgucuu ccccagcgac     1440

gaguuugacg ccucaaucuc gcaagucaau gaaaagauua accaaucccu agccuucauc     1500

cgaaaaagug acgaacuccu ccacaacguu aacgccggca aaucuacaac caacaucaug     1560

aucaccacua uaaucaucgu caucauaguc auacuucuca gccucaucgc agucggacuc     1620

cuccuuuauu gcaaggcacg auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  6746
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6746
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac cccgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6747
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6747
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gaugcucaug ugcagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc uggaggggga ggugaacaag      480

aucaagagcg cccuccuguc caccaacaag gccgugguca gccuguccaa cggcgugagc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc aguccugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggggu caccacgccc      720

gugagcaccu acaugcugac caacuccgag cuccugagcc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggcgugaucg acacgcccug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggga gcaacaucug ccucacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc gcaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggggccau cguguccugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

gucgacacgg uguccguggg gaacacccug uacuacguca acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggca aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cguggggcug     1620

cuccuguacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6748
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6748
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac cccgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6749
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6749
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugaccugca gaugcuuaug uguuccacac ccgccaccgg gucuggaucg      420

gcuauagcau caggcguggc cgucugcaag gugcugcacu uggaggguga gguuaacaaa      480

aucaagagcg cucuccugag uacgaauaaa gccguggucu cccugucuaa cggggugagc      540

guacucacuu uuaagguuuu agaucugaag aauuacauug acaaacagcu uuugccuauc      600

cugaacaagc aauccuguuc aauuccaaau ccggaaaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau cacacgggag uuuaguguca acgcgggagu gacuaccccc      720

gugagcacau auaugcugac caauucugag cuucuguccu ugauaaacga uaugccuauu      780

acgaacgacc agaagaaacu caugucaaau aacguccaaa ucguucgcca gcagagcuac      840

aguauuaugu gcaucaucaa ggaagaggug cuggcauaug uagugcaguu accacuguac      900

ggcgucauug auacucccug uuggaaacuc cauacaucuc cucuuugcac cacuaauaca      960

aaggaaggcu ccaacauaug ucugacccga acggaccgug ggugguacug cgauaaugcc     1020

ggaagcgugu cguucuuucc acaagcugag accuguaagg uuugcucuaa cagaguguuc     1080

ugcgacacaa ugaacuccuu gacucuaccc ucagaaguca aucuguguaa uguggauauc     1140

uuuaacccua aauaugacug caagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ucggugccau agugucaugu uacggcaaga ccaaaugcac agcaaguaau     1260

aagaacaagg ggauuaucaa aaccuucucc aauggaugug acuaugucag caacaagggc     1320

guggacacug ucucuguggg uaauacgcug uacuauguua acaaacagga ggggcaguca     1380

cuuuacguga agggagagcc aaucauuaac uuuuaugauc cgcugguauu ccccagugac     1440

gaauuugaug cuagcaucuc ccaagucaau gagaaaauua accagucuuu ggccuucaua     1500

aggaagucgg acgaacuccu gcacaaugug aacgcgggca agagcacaac caauaucaug     1560

auuacuacca ucaucauugu uauaaucgug auuuuacugu cccuaaucgc cgucggccuc     1620

cugcuuuacu gcaaagcacg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6750
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6750
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac cccgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6751
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6751
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagaau      300

aaaugcaacg ggaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggaccucca gaugcugaug uguagcaccc ccgccacagg auccggcucu      420

gcuauugcca gcggggucgc ggugugcaag guucugcacc ucgagggaga ggugaacaaa      480

aucaaguccg cccugcuuag caccaauaaa gcugucgugu cucuguccaa cggcguuagc      540

gugcucacau uuaagguccu ggaucuuaag aauuacauug acaaacagcu gcucccuauc      600

cugaacaagc aaucuuguuc cauuccgaau cccgaaaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau cacgcgcgag uuuagcguga acgccggcgu cacaaccccu      720

guuucuacau auaugcugac caauuccgag cuucugagcc ucauuaacga uaugcccauc      780

accaacgacc agaagaaacu gauguccaau aacgugcaaa ucgugagaca gcagucuuac      840

agcauuaugu gcaucauuaa ggaagagguc cuugcuuaug ugguucagcu gccucucuac      900

ggggugaucg auacacccug uuggaaacug cauacguccc cucugugcac cacaaauacc      960

aaggaaggaa gcaacauuug ucucacacgg accgaccgcg gcugguacug cgauaaugcc     1020

gggucugucu ccuucuuucc gcaagcggag acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu gacccuuccc agcgaaguga aucuguguaa ugucgauauc     1140

uuuaacccua aauaugacug caagaucaug accuccaaaa cagauguguc uagcuccguc     1200

auuaccagcc ucggagccau cgugucuugu uacggcaaga caaaaugcac ggcuuccaau     1260

aagaacaagg ggauuaucaa aaccuucagc aauggaugug acuauguuuc uaacaagggc     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga ggggcagagc     1380

cuuuacguga agggagagcc cauuaucaac uuuuaugauc cucuggucuu ccccuccgac     1440

gaauuugaug ccucuaucag ccaagugaau gagaaaauua accagucccu cgcuuucauc     1500

cggaagucug acgaacugcu gcacaaugug aacgccggca agagcacaac caauauuaug     1560

aucacgacca uuaucauugu uaucaucguc auucuccugu cccuuaucgc cguggggcug     1620

cuccuguacu gcaaagcucg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6752
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6752
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauuaaaa      120

gcaaacgcaa uaacaacgau auuaacagcu guaacauucu gcuuugcauc aggccaaaau      180

aucaccgaag aauuuuauca aagcacaugc ucugcaguau ccaaaggaua cuuaggagca      240

uuaagaacag gcugguacac auccguaaua acaauagaac uaucaaacau caaagaaaac      300

aaaugcaacg gcacagacgc caaaguaaaa cucauaaaac aagaacuaga caaauauaaa      360

aacgcaguaa cagaucuaca aaugcucaug ugcuccacac cagcaaccgg aucugguuca      420

gccauagcau ccggcguagc cgucugcaaa guauuacacc ucgaaggaga aguaaacaaa      480

auaaaaucug cccuauuauc uacaaauaaa gccguaguaa gucuaaguaa cggaguauca      540

guacuaacau uuaaaguccu agaccugaaa aacuauaucg acaaacaacu auuaccaaua      600

cuaaacaaac aauccuguuc caucccuaac ccagaaacag uuauggaauu ucaacaaaaa      660

aauaaccgcc uuuuagaaau aacuagagaa uuuucaguaa acgcaggagu uacaacacca      720

guaucaacau acaugcuaac aaauucagaa uuauuauccc uuauaaauga caugccuauc      780

acaaacgauc aaaaaaaauu aauguccaac aacguacaaa uaguaagaca acaaucauau      840

uccaucaugu gcaucauaaa agaagaaguc cucgcauacg uagugcaacu accacuauac      900

ggagucauag auacacccug uuggaaacuu cacacaucuc cacuaugcac aacaaacacg      960

aaagaaggau ccaacauaug ccuaacacga acagacagag gaugguauug cgacaacgcu     1020

ggaaguguga gcuucuuccc ucaagcagaa acuugcaaag uaugcagcaa ucguguauuc     1080

ugcgacacaa ugaacucauu aacacuccca agcgaaguaa accucugcaa uguagacauc     1140

uuuaauccaa aauacgauug uaaaauaaug acuucaaaaa cagacgucuc aucaucugua     1200

auaacaucuu uaggagcaau aguuucuugc uacgguaaaa caaaaugcac cgcauccaac     1260

aaaaacaaag gaauaauaaa aacauucucu aacggcugcg auuacguauc uaacaaagga     1320

guugacacag ucucaguagg aaacacacua uacuacguaa acaaacaaga aggacaaagc     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cauuaguauu uccaagcgau     1440

gaauuugacg cuucaauauc acaagucaau gaaaaaauaa aucagagcuu agcauucaua     1500

agaaaaucug augaacuacu acacaaugua aaugcaggaa aauccacuac caacauaaug     1560

auuaccacaa uuauaauagu uaucauagua auacuauuau cacuaauagc cguuggauua     1620

cuacuauacu gcaaagcaag auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6753
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6753
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauccuaaaa      120

gcaaacgcca ucaccaccau acuaaccgcc gucaccuucu gcuucgccuc gggacaaaac      180

aucaccgaag aguucuacca gucaacgugc uccgccgucu caaaaggcua ccuaggcgcc      240

cuccgcaccg ggugguauac cuccgucaua acuaucgaac ucucuaacau caaagaaaac      300

aaauguaacg gcaccgacgc caaagucaaa cuaaucaaac aagaacugga caaauacaaa      360

aacgccguca ccgaccuaca aaugcucaug ugcuccacuc cagccaccgg cuccgguagc      420

gcaaucgccu caggcguagc uguaugcaaa guccuccacc uagaaggcga aguaaacaaa      480

auaaaauccg cccuccucuc aaccaacaag gccgucgucu cacucucaaa cggcgucucc      540

guacucaccu uuaaaguccu agaccuuaaa aacuacaucg acaaacaacu gcuaccaauc      600

cucaacaaac aaucaugcag caucccaaac ccggaaacag ucauggaguu ccaacagaaa      660

aacaaccgac uccucgaaau cacccgcgag uucuccguca acgccggagu caccacaccu      720

guaagcacau acaugcuuac uaauuccgaa cuccuuucac uaauaaacga caugccaaua      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguacgcca acaauccuac      840

uccaucaugu gcaucaucaa agaagaaguc cuggccuaug ucguacaacu cccccuuuac      900

ggugucaucg acacacccug cuggaaacua cacaccagcc cccucugcac aacaaacacc      960

aaagaaggcu ccaacaucug ccucacccgu accgaccgag gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaagccgaa accugcaaag ucugcagcaa ccgcgucuuc     1080

ugcgauacca ugaacucccu cacacuccca ucugaaguca accucugcaa cgucgauauu     1140

uucaauccaa aauacgacug caaaaucaug acuagcaaaa ccgacguuag cuccuccguc     1200

aucaccuccc ucggcgccau aguuucaugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aaccuucucc aacgggugcg acuacguauc uaauaaagga     1320

gucgacaccg ucucaguagg aaacacccuc uacuauguca acaaacaaga aggccaauca     1380

cuauacguua aaggcgaacc aaucaucaac uucuacgacc cacucgucuu ccccagcgac     1440

gaguuugacg ccucaaucuc gcaagucaau gaaaagauua accaaucccu agccuucauc     1500

cgaaaaagug acgaacuccu ccacaacguu aacgccggca aaucuacaac caacaucaug     1560

aucaccacua uaaucaucgu caucauaguc auacuucuca gccucaucgc agucggacuc     1620

cuccuuuauu gcaaggcacg auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6754
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6754
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6755
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6755
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6756
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6756
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6757
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6757
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6758
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6758
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6759
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6759
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6760
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6760
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau uaaaagcaaa cgcaauaaca acgauauuaa cagcuguaac auucugcuuu      240

gcaucaggcc aaaauaucac cgaagaauuu uaucaaagca caugcucugc aguauccaaa      300

ggauacuuag gagcauuaag aacaggcugg uacacauccg uaauaacaau agaacuauca      360

aacaucaaag aaaacaaaug caacggcaca gacgccaaag uaaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacagau cuacaaaugc ucaugugcuc cacaccagca      480

accggaucug guucagccau agcauccggc guagccgucu gcaaaguauu acaccucgaa      540

ggagaaguaa acaaaauaaa aucugcccua uuaucuacaa auaaagccgu aguaagucua      600

aguaacggag uaucaguacu aacauuuaaa guccuagacc ugaaaaacua uaucgacaaa      660

caacuauuac caauacuaaa caaacaaucc uguuccaucc cuaacccaga aacaguuaug      720

gaauuucaac aaaaaaauaa ccgccuuuua gaaauaacua gagaauuuuc aguaaacgca      780

ggaguuacaa caccaguauc aacauacaug cuaacaaauu cagaauuauu aucccuuaua      840

aaugacaugc cuaucacaaa cgaucaaaaa aaauuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauauuccau caugugcauc auaaaagaag aaguccucgc auacguagug      960

caacuaccac uauacggagu cauagauaca cccuguugga aacuucacac aucuccacua     1020

ugcacaacaa acacgaaaga aggauccaac auaugccuaa cacgaacaga cagaggaugg     1080

uauugcgaca acgcuggaag ugugagcuuc uucccucaag cagaaacuug caaaguaugc     1140

agcaaucgug uauucugcga cacaaugaac ucauuaacac ucccaagcga aguaaaccuc     1200

ugcaauguag acaucuuuaa uccaaaauac gauuguaaaa uaaugacuuc aaaaacagac     1260

gucucaucau cuguaauaac aucuuuagga gcaauaguuu cuugcuacgg uaaaacaaaa     1320

ugcaccgcau ccaacaaaaa caaaggaaua auaaaaacau ucucuaacgg cugcgauuac     1380

guaucuaaca aaggaguuga cacagucuca guaggaaaca cacuauacua cguaaacaaa     1440

caagaaggac aaagccuaua cguaaaagga gaaccaauaa uaaacuucua ugacccauua     1500

guauuuccaa gcgaugaauu ugacgcuuca auaucacaag ucaaugaaaa aauaaaucag     1560

agcuuagcau ucauaagaaa aucugaugaa cuacuacaca auguaaaugc aggaaaaucc     1620

acuaccaaca uaaugauuac cacaauuaua auaguuauca uaguaauacu auuaucacua     1680

auagccguug gauuacuacu auacugcaaa gcaagauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6761
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6761
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagcaaa cgccaucacc accauacuaa ccgccgucac cuucugcuuc      240

gccucgggac aaaacaucac cgaagaguuc uaccagucaa cgugcuccgc cgucucaaaa      300

ggcuaccuag gcgcccuccg caccgggugg uauaccuccg ucauaacuau cgaacucucu      360

aacaucaaag aaaacaaaug uaacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cuggacaaau acaaaaacgc cgucaccgac cuacaaaugc ucaugugcuc cacuccagcc      480

accggcuccg guagcgcaau cgccucaggc guagcuguau gcaaaguccu ccaccuagaa      540

ggcgaaguaa acaaaauaaa auccgcccuc cucucaacca acaaggccgu cgucucacuc      600

ucaaacggcg ucuccguacu caccuuuaaa guccuagacc uuaaaaacua caucgacaaa      660

caacugcuac caauccucaa caaacaauca ugcagcaucc caaacccgga aacagucaug      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggagucacca caccuguaag cacauacaug cuuacuaauu ccgaacuccu uucacuaaua      840

aacgacaugc caauaaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucgua      900

cgccaacaau ccuacuccau caugugcauc aucaaagaag aaguccuggc cuaugucgua      960

caacuccccc uuuacggugu caucgacaca cccugcugga aacuacacac cagcccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccguaccga ccgaggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaaccug caaagucugc     1140

agcaaccgcg ucuucugcga uaccaugaac ucccucacac ucccaucuga agucaaccuc     1200

ugcaacgucg auauuuucaa uccaaaauac gacugcaaaa ucaugacuag caaaaccgac     1260

guuagcuccu ccgucaucac cucccucggc gccauaguuu caugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaaccu ucuccaacgg gugcgacuac     1380

guaucuaaua aaggagucga caccgucuca guaggaaaca cccucuacua ugucaacaaa     1440

caagaaggcc aaucacuaua cguuaaaggc gaaccaauca ucaacuucua cgacccacuc     1500

gucuucccca gcgacgaguu ugacgccuca aucucgcaag ucaaugaaaa gauuaaccaa     1560

ucccuagccu ucauccgaaa aagugacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

acaaccaaca ucaugaucac cacuauaauc aucgucauca uagucauacu ucucagccuc     1680

aucgcagucg gacuccuccu uuauugcaag gcacgauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  6762
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6762
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6763
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6763
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6764
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6764
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6765
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6765
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6766
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6766
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6767
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6767
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6768
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6768
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau uaaaagcaaa cgcaauaaca acgauauuaa cagcuguaac auucugcuuu      240

gcaucaggcc aaaauaucac cgaagaauuu uaucaaagca caugcucugc aguauccaaa      300

ggauacuuag gagcauuaag aacaggcugg uacacauccg uaauaacaau agaacuauca      360

aacaucaaag aaaacaaaug caacggcaca gacgccaaag uaaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacagau cuacaaaugc ucaugugcuc cacaccagca      480

accggaucug guucagccau agcauccggc guagccgucu gcaaaguauu acaccucgaa      540

ggagaaguaa acaaaauaaa aucugcccua uuaucuacaa auaaagccgu aguaagucua      600

aguaacggag uaucaguacu aacauuuaaa guccuagacc ugaaaaacua uaucgacaaa      660

caacuauuac caauacuaaa caaacaaucc uguuccaucc cuaacccaga aacaguuaug      720

gaauuucaac aaaaaaauaa ccgccuuuua gaaauaacua gagaauuuuc aguaaacgca      780

ggaguuacaa caccaguauc aacauacaug cuaacaaauu cagaauuauu aucccuuaua      840

aaugacaugc cuaucacaaa cgaucaaaaa aaauuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauauuccau caugugcauc auaaaagaag aaguccucgc auacguagug      960

caacuaccac uauacggagu cauagauaca cccuguugga aacuucacac aucuccacua     1020

ugcacaacaa acacgaaaga aggauccaac auaugccuaa cacgaacaga cagaggaugg     1080

uauugcgaca acgcuggaag ugugagcuuc uucccucaag cagaaacuug caaaguaugc     1140

agcaaucgug uauucugcga cacaaugaac ucauuaacac ucccaagcga aguaaaccuc     1200

ugcaauguag acaucuuuaa uccaaaauac gauuguaaaa uaaugacuuc aaaaacagac     1260

gucucaucau cuguaauaac aucuuuagga gcaauaguuu cuugcuacgg uaaaacaaaa     1320

ugcaccgcau ccaacaaaaa caaaggaaua auaaaaacau ucucuaacgg cugcgauuac     1380

guaucuaaca aaggaguuga cacagucuca guaggaaaca cacuauacua cguaaacaaa     1440

caagaaggac aaagccuaua cguaaaagga gaaccaauaa uaaacuucua ugacccauua     1500

guauuuccaa gcgaugaauu ugacgcuuca auaucacaag ucaaugaaaa aauaaaucag     1560

agcuuagcau ucauaagaaa aucugaugaa cuacuacaca auguaaaugc aggaaaaucc     1620

acuaccaaca uaaugauuac cacaauuaua auaguuauca uaguaauacu auuaucacua     1680

auagccguug gauuacuacu auacugcaaa gcaagauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6769
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6769
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagcaaa cgccaucacc accauacuaa ccgccgucac cuucugcuuc      240

gccucgggac aaaacaucac cgaagaguuc uaccagucaa cgugcuccgc cgucucaaaa      300

ggcuaccuag gcgcccuccg caccgggugg uauaccuccg ucauaacuau cgaacucucu      360

aacaucaaag aaaacaaaug uaacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cuggacaaau acaaaaacgc cgucaccgac cuacaaaugc ucaugugcuc cacuccagcc      480

accggcuccg guagcgcaau cgccucaggc guagcuguau gcaaaguccu ccaccuagaa      540

ggcgaaguaa acaaaauaaa auccgcccuc cucucaacca acaaggccgu cgucucacuc      600

ucaaacggcg ucuccguacu caccuuuaaa guccuagacc uuaaaaacua caucgacaaa      660

caacugcuac caauccucaa caaacaauca ugcagcaucc caaacccgga aacagucaug      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggagucacca caccuguaag cacauacaug cuuacuaauu ccgaacuccu uucacuaaua      840

aacgacaugc caauaaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucgua      900

cgccaacaau ccuacuccau caugugcauc aucaaagaag aaguccuggc cuaugucgua      960

caacuccccc uuuacggugu caucgacaca cccugcugga aacuacacac cagcccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccguaccga ccgaggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaaccug caaagucugc     1140

agcaaccgcg ucuucugcga uaccaugaac ucccucacac ucccaucuga agucaaccuc     1200

ugcaacgucg auauuuucaa uccaaaauac gacugcaaaa ucaugacuag caaaaccgac     1260

guuagcuccu ccgucaucac cucccucggc gccauaguuu caugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaaccu ucuccaacgg gugcgacuac     1380

guaucuaaua aaggagucga caccgucuca guaggaaaca cccucuacua ugucaacaaa     1440

caagaaggcc aaucacuaua cguuaaaggc gaaccaauca ucaacuucua cgacccacuc     1500

gucuucccca gcgacgaguu ugacgccuca aucucgcaag ucaaugaaaa gauuaaccaa     1560

ucccuagccu ucauccgaaa aagugacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

acaaccaaca ucaugaucac cacuauaauc aucgucauca uagucauacu ucucagccuc     1680

aucgcagucg gacuccuccu uuauugcaag gcacgauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  6770
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6770
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccaucc ccaaccccga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6771
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6771
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagaugc ucaugugcag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccuggag      540

ggggagguga acaagaucaa gagcgcccuc cuguccacca acaaggccgu ggucagccug      600

uccaacggcg ugagcgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagucc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggggucacca cgcccgugag caccuacaug cugaccaacu ccgagcuccu gagccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggcgu gaucgacacg cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga ggggagcaac aucugccuca cccgcaccga ccggggcugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccgcagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggg gccaucgugu ccugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgucga cacggugucc guggggaaca cccuguacua cgucaacaag     1440

caggagggcc agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cggcaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg ggcugcuccu guacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6772
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6772
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucc ccaaccccga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggcc agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6773
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6773
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaauaaaug caacggcacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugac cugcagaugc uuauguguuc cacacccgcc      480

accgggucug gaucggcuau agcaucaggc guggccgucu gcaaggugcu gcacuuggag      540

ggugagguua acaaaaucaa gagcgcucuc cugaguacga auaaagccgu ggucucccug      600

ucuaacgggg ugagcguacu cacuuuuaag guuuuagauc ugaagaauua cauugacaaa      660

cagcuuuugc cuauccugaa caagcaaucc uguucaauuc caaauccgga aaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaaucacac gggaguuuag ugucaacgcg      780

ggagugacua cccccgugag cacauauaug cugaccaauu cugagcuucu guccuugaua      840

aacgauaugc cuauuacgaa cgaccagaag aaacucaugu caaauaacgu ccaaaucguu      900

cgccagcaga gcuacaguau uaugugcauc aucaaggaag aggugcuggc auauguagug      960

caguuaccac uguacggcgu cauugauacu cccuguugga aacuccauac aucuccucuu     1020

ugcaccacua auacaaagga aggcuccaac auaugucuga cccgaacgga ccgugggugg     1080

uacugcgaua augccggaag cgugucguuc uuuccacaag cugagaccug uaagguuugc     1140

ucuaacagag uguucugcga cacaaugaac uccuugacuc uacccucaga agucaaucug     1200

uguaaugugg auaucuuuaa cccuaaauau gacugcaaga uuaugaccag uaaaacagau     1260

guaagcuccu cuguuaucac uagccucggu gccauagugu cauguuacgg caagaccaaa     1320

ugcacagcaa guaauaagaa caaggggauu aucaaaaccu ucuccaaugg augugacuau     1380

gucagcaaca agggcgugga cacugucucu guggguaaua cgcuguacua uguuaacaaa     1440

caggaggggc agucacuuua cgugaaggga gagccaauca uuaacuuuua ugauccgcug     1500

guauucccca gugacgaauu ugaugcuagc aucucccaag ucaaugagaa aauuaaccag     1560

ucuuuggccu ucauaaggaa gucggacgaa cuccugcaca augugaacgc gggcaagagc     1620

acaaccaaua ucaugauuac uaccaucauc auuguuauaa ucgugauuuu acugucccua     1680

aucgccgucg gccuccugcu uuacugcaaa gcacggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6774
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6774
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcaucc ccaaccccga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggcc agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6775
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6775
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaauaaaug caacgggacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggac cuccagaugc ugauguguag cacccccgcc      480

acaggauccg gcucugcuau ugccagcggg gucgcggugu gcaagguucu gcaccucgag      540

ggagagguga acaaaaucaa guccgcccug cuuagcacca auaaagcugu cgugucucug      600

uccaacggcg uuagcgugcu cacauuuaag guccuggauc uuaagaauua cauugacaaa      660

cagcugcucc cuauccugaa caagcaaucu uguuccauuc cgaaucccga aaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaaucacgc gcgaguuuag cgugaacgcc      780

ggcgucacaa ccccuguuuc uacauauaug cugaccaauu ccgagcuucu gagccucauu      840

aacgauaugc ccaucaccaa cgaccagaag aaacugaugu ccaauaacgu gcaaaucgug      900

agacagcagu cuuacagcau uaugugcauc auuaaggaag agguccuugc uuaugugguu      960

cagcugccuc ucuacggggu gaucgauaca cccuguugga aacugcauac guccccucug     1020

ugcaccacaa auaccaagga aggaagcaac auuugucuca cacggaccga ccgcggcugg     1080

uacugcgaua augccggguc ugucuccuuc uuuccgcaag cggagacgug uaaggugugc     1140

agcaacagag uuuucugcga cacaaugaac ucucugaccc uucccagcga agugaaucug     1200

uguaaugucg auaucuuuaa cccuaaauau gacugcaaga ucaugaccuc caaaacagau     1260

gugucuagcu ccgucauuac cagccucgga gccaucgugu cuuguuacgg caagacaaaa     1320

ugcacggcuu ccaauaagaa caaggggauu aucaaaaccu ucagcaaugg augugacuau     1380

guuucuaaca agggcgugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggaggggc agagccuuua cgugaaggga gagcccauua ucaacuuuua ugauccucug     1500

gucuuccccu ccgacgaauu ugaugccucu aucagccaag ugaaugagaa aauuaaccag     1560

ucccucgcuu ucauccggaa gucugacgaa cugcugcaca augugaacgc cggcaagagc     1620

acaaccaaua uuaugaucac gaccauuauc auuguuauca ucgucauucu ccugucccuu     1680

aucgccgugg ggcugcuccu guacugcaaa gcucgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6776
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6776
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau uaaaagcaaa cgcaauaaca acgauauuaa cagcuguaac auucugcuuu      240

gcaucaggcc aaaauaucac cgaagaauuu uaucaaagca caugcucugc aguauccaaa      300

ggauacuuag gagcauuaag aacaggcugg uacacauccg uaauaacaau agaacuauca      360

aacaucaaag aaaacaaaug caacggcaca gacgccaaag uaaaacucau aaaacaagaa      420

cuagacaaau auaaaaacgc aguaacagau cuacaaaugc ucaugugcuc cacaccagca      480

accggaucug guucagccau agcauccggc guagccgucu gcaaaguauu acaccucgaa      540

ggagaaguaa acaaaauaaa aucugcccua uuaucuacaa auaaagccgu aguaagucua      600

aguaacggag uaucaguacu aacauuuaaa guccuagacc ugaaaaacua uaucgacaaa      660

caacuauuac caauacuaaa caaacaaucc uguuccaucc cuaacccaga aacaguuaug      720

gaauuucaac aaaaaaauaa ccgccuuuua gaaauaacua gagaauuuuc aguaaacgca      780

ggaguuacaa caccaguauc aacauacaug cuaacaaauu cagaauuauu aucccuuaua      840

aaugacaugc cuaucacaaa cgaucaaaaa aaauuaaugu ccaacaacgu acaaauagua      900

agacaacaau cauauuccau caugugcauc auaaaagaag aaguccucgc auacguagug      960

caacuaccac uauacggagu cauagauaca cccuguugga aacuucacac aucuccacua     1020

ugcacaacaa acacgaaaga aggauccaac auaugccuaa cacgaacaga cagaggaugg     1080

uauugcgaca acgcuggaag ugugagcuuc uucccucaag cagaaacuug caaaguaugc     1140

agcaaucgug uauucugcga cacaaugaac ucauuaacac ucccaagcga aguaaaccuc     1200

ugcaauguag acaucuuuaa uccaaaauac gauuguaaaa uaaugacuuc aaaaacagac     1260

gucucaucau cuguaauaac aucuuuagga gcaauaguuu cuugcuacgg uaaaacaaaa     1320

ugcaccgcau ccaacaaaaa caaaggaaua auaaaaacau ucucuaacgg cugcgauuac     1380

guaucuaaca aaggaguuga cacagucuca guaggaaaca cacuauacua cguaaacaaa     1440

caagaaggac aaagccuaua cguaaaagga gaaccaauaa uaaacuucua ugacccauua     1500

guauuuccaa gcgaugaauu ugacgcuuca auaucacaag ucaaugaaaa aauaaaucag     1560

agcuuagcau ucauaagaaa aucugaugaa cuacuacaca auguaaaugc aggaaaaucc     1620

acuaccaaca uaaugauuac cacaauuaua auaguuauca uaguaauacu auuaucacua     1680

auagccguug gauuacuacu auacugcaaa gcaagauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6777
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6777
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucaucc uaaaagcaaa cgccaucacc accauacuaa ccgccgucac cuucugcuuc      240

gccucgggac aaaacaucac cgaagaguuc uaccagucaa cgugcuccgc cgucucaaaa      300

ggcuaccuag gcgcccuccg caccgggugg uauaccuccg ucauaacuau cgaacucucu      360

aacaucaaag aaaacaaaug uaacggcacc gacgccaaag ucaaacuaau caaacaagaa      420

cuggacaaau acaaaaacgc cgucaccgac cuacaaaugc ucaugugcuc cacuccagcc      480

accggcuccg guagcgcaau cgccucaggc guagcuguau gcaaaguccu ccaccuagaa      540

ggcgaaguaa acaaaauaaa auccgcccuc cucucaacca acaaggccgu cgucucacuc      600

ucaaacggcg ucuccguacu caccuuuaaa guccuagacc uuaaaaacua caucgacaaa      660

caacugcuac caauccucaa caaacaauca ugcagcaucc caaacccgga aacagucaug      720

gaguuccaac agaaaaacaa ccgacuccuc gaaaucaccc gcgaguucuc cgucaacgcc      780

ggagucacca caccuguaag cacauacaug cuuacuaauu ccgaacuccu uucacuaaua      840

aacgacaugc caauaaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucgua      900

cgccaacaau ccuacuccau caugugcauc aucaaagaag aaguccuggc cuaugucgua      960

caacuccccc uuuacggugu caucgacaca cccugcugga aacuacacac cagcccccuc     1020

ugcacaacaa acaccaaaga aggcuccaac aucugccuca cccguaccga ccgaggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccaag ccgaaaccug caaagucugc     1140

agcaaccgcg ucuucugcga uaccaugaac ucccucacac ucccaucuga agucaaccuc     1200

ugcaacgucg auauuuucaa uccaaaauac gacugcaaaa ucaugacuag caaaaccgac     1260

guuagcuccu ccgucaucac cucccucggc gccauaguuu caugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaaccu ucuccaacgg gugcgacuac     1380

guaucuaaua aaggagucga caccgucuca guaggaaaca cccucuacua ugucaacaaa     1440

caagaaggcc aaucacuaua cguuaaaggc gaaccaauca ucaacuucua cgacccacuc     1500

gucuucccca gcgacgaguu ugacgccuca aucucgcaag ucaaugaaaa gauuaaccaa     1560

ucccuagccu ucauccgaaa aagugacgaa cuccuccaca acguuaacgc cggcaaaucu     1620

acaaccaaca ucaugaucac cacuauaauc aucgucauca uagucauacu ucucagccuc     1680

aucgcagucg gacuccuccu uuauugcaag gcacgauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6778
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6778
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaaccc cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6779
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6779
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcaga ugcucaugug cagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggggagg ugaacaagau caagagcgcc cuccugucca ccaacaaggc cguggucagc      480

cuguccaacg gcgugagcgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag uccugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccgggguca ccacgcccgu gagcaccuac augcugacca acuccgagcu ccugagccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg cgugaucgac acgcccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggaggggagc aacaucugcc ucacccgcac cgaccggggc      960

ugguacugcg acaacgcggg cuccgugagc uucuucccgc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggggccaucg uguccugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu cgacacggug uccgugggga acacccugua cuacgucaac     1320

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccggcaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg uggggcugcu ccuguacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6780
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6780
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaaccc cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6781
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6781
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaauaa augcaacggc accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gaccugcaga ugcuuaugug uuccacaccc      360

gccaccgggu cuggaucggc uauagcauca ggcguggccg ucugcaaggu gcugcacuug      420

gagggugagg uuaacaaaau caagagcgcu cuccugagua cgaauaaagc cguggucucc      480

cugucuaacg gggugagcgu acucacuuuu aagguuuuag aucugaagaa uuacauugac      540

aaacagcuuu ugccuauccu gaacaagcaa uccuguucaa uuccaaaucc ggaaaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauca cacgggaguu uagugucaac      660

gcgggaguga cuacccccgu gagcacauau augcugacca auucugagcu ucuguccuug      720

auaaacgaua ugccuauuac gaacgaccag aagaaacuca ugucaaauaa cguccaaauc      780

guucgccagc agagcuacag uauuaugugc aucaucaagg aagaggugcu ggcauaugua      840

gugcaguuac cacuguacgg cgucauugau acucccuguu ggaaacucca uacaucuccu      900

cuuugcacca cuaauacaaa ggaaggcucc aacauauguc ugacccgaac ggaccguggg      960

ugguacugcg auaaugccgg aagcgugucg uucuuuccac aagcugagac cuguaagguu     1020

ugcucuaaca gaguguucug cgacacaaug aacuccuuga cucuacccuc agaagucaau     1080

cuguguaaug uggauaucuu uaacccuaaa uaugacugca agauuaugac caguaaaaca     1140

gauguaagcu ccucuguuau cacuagccuc ggugccauag ugucauguua cggcaagacc     1200

aaaugcacag caaguaauaa gaacaagggg auuaucaaaa ccuucuccaa uggaugugac     1260

uaugucagca acaagggcgu ggacacuguc ucugugggua auacgcugua cuauguuaac     1320

aaacaggagg ggcagucacu uuacgugaag ggagagccaa ucauuaacuu uuaugauccg     1380

cugguauucc ccagugacga auuugaugcu agcaucuccc aagucaauga gaaaauuaac     1440

cagucuuugg ccuucauaag gaagucggac gaacuccugc acaaugugaa cgcgggcaag     1500

agcacaacca auaucaugau uacuaccauc aucauuguua uaaucgugau uuuacugucc     1560

cuaaucgccg ucggccuccu gcuuuacugc aaagcacggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6782
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6782
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaaccc cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6783
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6783
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaauaa augcaacggg accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gaccuccaga ugcugaugug uagcaccccc      360

gccacaggau ccggcucugc uauugccagc ggggucgcgg ugugcaaggu ucugcaccuc      420

gagggagagg ugaacaaaau caaguccgcc cugcuuagca ccaauaaagc ugucgugucu      480

cuguccaacg gcguuagcgu gcucacauuu aagguccugg aucuuaagaa uuacauugac      540

aaacagcugc ucccuauccu gaacaagcaa ucuuguucca uuccgaaucc cgaaaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauca cgcgcgaguu uagcgugaac      660

gccggcguca caaccccugu uucuacauau augcugacca auuccgagcu ucugagccuc      720

auuaacgaua ugcccaucac caacgaccag aagaaacuga uguccaauaa cgugcaaauc      780

gugagacagc agucuuacag cauuaugugc aucauuaagg aagagguccu ugcuuaugug      840

guucagcugc cucucuacgg ggugaucgau acacccuguu ggaaacugca uacguccccu      900

cugugcacca caaauaccaa ggaaggaagc aacauuuguc ucacacggac cgaccgcggc      960

ugguacugcg auaaugccgg gucugucucc uucuuuccgc aagcggagac guguaaggug     1020

ugcagcaaca gaguuuucug cgacacaaug aacucucuga cccuucccag cgaagugaau     1080

cuguguaaug ucgauaucuu uaacccuaaa uaugacugca agaucaugac cuccaaaaca     1140

gaugugucua gcuccgucau uaccagccuc ggagccaucg ugucuuguua cggcaagaca     1200

aaaugcacgg cuuccaauaa gaacaagggg auuaucaaaa ccuucagcaa uggaugugac     1260

uauguuucua acaagggcgu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg ggcagagccu uuacgugaag ggagagccca uuaucaacuu uuaugauccu     1380

cuggucuucc ccuccgacga auuugaugcc ucuaucagcc aagugaauga gaaaauuaac     1440

cagucccucg cuuucauccg gaagucugac gaacugcugc acaaugugaa cgccggcaag     1500

agcacaacca auauuaugau cacgaccauu aucauuguua ucaucgucau ucuccugucc     1560

cuuaucgccg uggggcugcu ccuguacugc aaagcucgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6784
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6784
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuca uauuaaaagc aaacgcaaua acaacgauau uaacagcugu aacauucugc      120

uuugcaucag gccaaaauau caccgaagaa uuuuaucaaa gcacaugcuc ugcaguaucc      180

aaaggauacu uaggagcauu aagaacaggc ugguacacau ccguaauaac aauagaacua      240

ucaaacauca aagaaaacaa augcaacggc acagacgcca aaguaaaacu cauaaaacaa      300

gaacuagaca aauauaaaaa cgcaguaaca gaucuacaaa ugcucaugug cuccacacca      360

gcaaccggau cugguucagc cauagcaucc ggcguagccg ucugcaaagu auuacaccuc      420

gaaggagaag uaaacaaaau aaaaucugcc cuauuaucua caaauaaagc cguaguaagu      480

cuaaguaacg gaguaucagu acuaacauuu aaaguccuag accugaaaaa cuauaucgac      540

aaacaacuau uaccaauacu aaacaaacaa uccuguucca ucccuaaccc agaaacaguu      600

auggaauuuc aacaaaaaaa uaaccgccuu uuagaaauaa cuagagaauu uucaguaaac      660

gcaggaguua caacaccagu aucaacauac augcuaacaa auucagaauu auuaucccuu      720

auaaaugaca ugccuaucac aaacgaucaa aaaaaauuaa uguccaacaa cguacaaaua      780

guaagacaac aaucauauuc caucaugugc aucauaaaag aagaaguccu cgcauacgua      840

gugcaacuac cacuauacgg agucauagau acacccuguu ggaaacuuca cacaucucca      900

cuaugcacaa caaacacgaa agaaggaucc aacauaugcc uaacacgaac agacagagga      960

ugguauugcg acaacgcugg aagugugagc uucuucccuc aagcagaaac uugcaaagua     1020

ugcagcaauc guguauucug cgacacaaug aacucauuaa cacucccaag cgaaguaaac     1080

cucugcaaug uagacaucuu uaauccaaaa uacgauugua aaauaaugac uucaaaaaca     1140

gacgucucau caucuguaau aacaucuuua ggagcaauag uuucuugcua cgguaaaaca     1200

aaaugcaccg cauccaacaa aaacaaagga auaauaaaaa cauucucuaa cggcugcgau     1260

uacguaucua acaaaggagu ugacacaguc ucaguaggaa acacacuaua cuacguaaac     1320

aaacaagaag gacaaagccu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1380

uuaguauuuc caagcgauga auuugacgcu ucaauaucac aagucaauga aaaaauaaau     1440

cagagcuuag cauucauaag aaaaucugau gaacuacuac acaauguaaa ugcaggaaaa     1500

uccacuacca acauaaugau uaccacaauu auaauaguua ucauaguaau acuauuauca     1560

cuaauagccg uuggauuacu acuauacugc aaagcaagau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6785
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6785
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuca uccuaaaagc aaacgccauc accaccauac uaaccgccgu caccuucugc      120

uucgccucgg gacaaaacau caccgaagag uucuaccagu caacgugcuc cgccgucuca      180

aaaggcuacc uaggcgcccu ccgcaccggg ugguauaccu ccgucauaac uaucgaacuc      240

ucuaacauca aagaaaacaa auguaacggc accgacgcca aagucaaacu aaucaaacaa      300

gaacuggaca aauacaaaaa cgccgucacc gaccuacaaa ugcucaugug cuccacucca      360

gccaccggcu ccgguagcgc aaucgccuca ggcguagcug uaugcaaagu ccuccaccua      420

gaaggcgaag uaaacaaaau aaaauccgcc cuccucucaa ccaacaaggc cgucgucuca      480

cucucaaacg gcgucuccgu acucaccuuu aaaguccuag accuuaaaaa cuacaucgac      540

aaacaacugc uaccaauccu caacaaacaa ucaugcagca ucccaaaccc ggaaacaguc      600

auggaguucc aacagaaaaa caaccgacuc cucgaaauca cccgcgaguu cuccgucaac      660

gccggaguca ccacaccugu aagcacauac augcuuacua auuccgaacu ccuuucacua      720

auaaacgaca ugccaauaac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      780

guacgccaac aauccuacuc caucaugugc aucaucaaag aagaaguccu ggccuauguc      840

guacaacucc cccuuuacgg ugucaucgac acacccugcu ggaaacuaca caccagcccc      900

cucugcacaa caaacaccaa agaaggcucc aacaucugcc ucacccguac cgaccgaggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aagccgaaac cugcaaaguc     1020

ugcagcaacc gcgucuucug cgauaccaug aacucccuca cacucccauc ugaagucaac     1080

cucugcaacg ucgauauuuu caauccaaaa uacgacugca aaaucaugac uagcaaaacc     1140

gacguuagcu ccuccgucau caccucccuc ggcgccauag uuucaugcua cggcaaaacc     1200

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa ccuucuccaa cgggugcgac     1260

uacguaucua auaaaggagu cgacaccguc ucaguaggaa acacccucua cuaugucaac     1320

aaacaagaag gccaaucacu auacguuaaa ggcgaaccaa ucaucaacuu cuacgaccca     1380

cucgucuucc ccagcgacga guuugacgcc ucaaucucgc aagucaauga aaagauuaac     1440

caaucccuag ccuucauccg aaaaagugac gaacuccucc acaacguuaa cgccggcaaa     1500

ucuacaacca acaucaugau caccacuaua aucaucguca ucauagucau acuucucagc     1560

cucaucgcag ucggacuccu ccuuuauugc aaggcacgau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  6786
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6786
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagaugcu gaugugcucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccauccc caaccccgag acggugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugugca     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac gugaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6787
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6787
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagaugcu caugugcagc acccccgcca      360

ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug caccuggagg      420

gggaggugaa caagaucaag agcgcccucc uguccaccaa caaggccgug gucagccugu      480

ccaacggcgu gagcgugcuc acguucaagg uccuggaccu gaagaacuac aucgacaagc      540

agcuccugcc gauccugaac aagcaguccu gcagcauccc caaccccgag accgugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc gugaacgccg      660

gggucaccac gcccgugagc accuacaugc ugaccaacuc cgagcuccug agccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcugccccu cuacggcgug aucgacacgc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa cacgaaggag gggagcaaca ucugccucac ccgcaccgac cggggcuggu      960

acugcgacaa cgcgggcucc gugagcuucu ucccgcaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag gucaaccucu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccuggggg ccaucguguc cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcgucgac acgguguccg uggggaacac ccuguacuac gucaacaagc     1320

aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc ggcaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug cucagccuga     1560

ucgccguggg gcugcuccug uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6788
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6788
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagaugcu caugugcucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccauccc caaccccgag accgucaugg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac gucaacaagc     1320

aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6789
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6789
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugacc ugcagaugcu uauguguucc acacccgcca      360

ccgggucugg aucggcuaua gcaucaggcg uggccgucug caaggugcug cacuuggagg      420

gugagguuaa caaaaucaag agcgcucucc ugaguacgaa uaaagccgug gucucccugu      480

cuaacggggu gagcguacuc acuuuuaagg uuuuagaucu gaagaauuac auugacaaac      540

agcuuuugcc uauccugaac aagcaauccu guucaauucc aaauccggaa accgugaugg      600

aguuccagca gaaaaacaau aggcuacucg aaaucacacg ggaguuuagu gucaacgcgg      660

gagugacuac ccccgugagc acauauaugc ugaccaauuc ugagcuucug uccuugauaa      720

acgauaugcc uauuacgaac gaccagaaga aacucauguc aaauaacguc caaaucguuc      780

gccagcagag cuacaguauu augugcauca ucaaggaaga ggugcuggca uauguagugc      840

aguuaccacu guacggcguc auugauacuc ccuguuggaa acuccauaca ucuccucuuu      900

gcaccacuaa uacaaaggaa ggcuccaaca uaugucugac ccgaacggac cguggguggu      960

acugcgauaa ugccggaagc gugucguucu uuccacaagc ugagaccugu aagguuugcu     1020

cuaacagagu guucugcgac acaaugaacu ccuugacucu acccucagaa gucaaucugu     1080

guaaugugga uaucuuuaac ccuaaauaug acugcaagau uaugaccagu aaaacagaug     1140

uaagcuccuc uguuaucacu agccucggug ccauaguguc auguuacggc aagaccaaau     1200

gcacagcaag uaauaagaac aaggggauua ucaaaaccuu cuccaaugga ugugacuaug     1260

ucagcaacaa gggcguggac acugucucug uggguaauac gcuguacuau guuaacaaac     1320

aggaggggca gucacuuuac gugaagggag agccaaucau uaacuuuuau gauccgcugg     1380

uauuccccag ugacgaauuu gaugcuagca ucucccaagu caaugagaaa auuaaccagu     1440

cuuuggccuu cauaaggaag ucggacgaac uccugcacaa ugugaacgcg ggcaagagca     1500

caaccaauau caugauuacu accaucauca uuguuauaau cgugauuuua cugucccuaa     1560

ucgccgucgg ccuccugcuu uacugcaaag cacggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6790
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6790
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagaugcu gaugugcagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcauccc caaccccgag accgugaugg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugugca     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac gugaacaagc     1320

aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6791
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6791
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaauaaaugc aacgggaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggacc uccagaugcu gauguguagc acccccgcca      360

caggauccgg cucugcuauu gccagcgggg ucgcggugug caagguucug caccucgagg      420

gagaggugaa caaaaucaag uccgcccugc uuagcaccaa uaaagcuguc gugucucugu      480

ccaacggcgu uagcgugcuc acauuuaagg uccuggaucu uaagaauuac auugacaaac      540

agcugcuccc uauccugaac aagcaaucuu guuccauucc gaaucccgaa accgugaugg      600

aguuccagca gaaaaacaau cggcugcucg aaaucacgcg cgaguuuagc gugaacgccg      660

gcgucacaac cccuguuucu acauauaugc ugaccaauuc cgagcuucug agccucauua      720

acgauaugcc caucaccaac gaccagaaga aacugauguc caauaacgug caaaucguga      780

gacagcaguc uuacagcauu augugcauca uuaaggaaga gguccuugcu uaugugguuc      840

agcugccucu cuacggggug aucgauacac ccuguuggaa acugcauacg uccccucugu      900

gcaccacaaa uaccaaggaa ggaagcaaca uuugucucac acggaccgac cgcggcuggu      960

acugcgauaa ugccgggucu gucuccuucu uuccgcaagc ggagacgugu aaggugugca     1020

gcaacagagu uuucugcgac acaaugaacu cucugacccu ucccagcgaa gugaaucugu     1080

guaaugucga uaucuuuaac ccuaaauaug acugcaagau caugaccucc aaaacagaug     1140

ugucuagcuc cgucauuacc agccucggag ccaucguguc uuguuacggc aagacaaaau     1200

gcacggcuuc caauaagaac aaggggauua ucaaaaccuu cagcaaugga ugugacuaug     1260

uuucuaacaa gggcguggac acagucuccg ugggcaauac ccuguacuau guuaacaaac     1320

aggaggggca gagccuuuac gugaagggag agcccauuau caacuuuuau gauccucugg     1380

ucuuccccuc cgacgaauuu gaugccucua ucagccaagu gaaugagaaa auuaaccagu     1440

cccucgcuuu cauccggaag ucugacgaac ugcugcacaa ugugaacgcc ggcaagagca     1500

caaccaauau uaugaucacg accauuauca uuguuaucau cgucauucuc cugucccuua     1560

ucgccguggg gcugcuccug uacugcaaag cucgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6792
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6792
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacucauauu aaaagcaaac gcaauaacaa cgauauuaac agcuguaaca uucugcuuug      120

caucaggcca aaauaucacc gaagaauuuu aucaaagcac augcucugca guauccaaag      180

gauacuuagg agcauuaaga acaggcuggu acacauccgu aauaacaaua gaacuaucaa      240

acaucaaaga aaacaaaugc aacggcacag acgccaaagu aaaacucaua aaacaagaac      300

uagacaaaua uaaaaacgca guaacagauc uacaaaugcu caugugcucc acaccagcaa      360

ccggaucugg uucagccaua gcauccggcg uagccgucug caaaguauua caccucgaag      420

gagaaguaaa caaaauaaaa ucugcccuau uaucuacaaa uaaagccgua guaagucuaa      480

guaacggagu aucaguacua acauuuaaag uccuagaccu gaaaaacuau aucgacaaac      540

aacuauuacc aauacuaaac aaacaauccu guuccauccc uaacccagaa acaguuaugg      600

aauuucaaca aaaaaauaac cgccuuuuag aaauaacuag agaauuuuca guaaacgcag      660

gaguuacaac accaguauca acauacaugc uaacaaauuc agaauuauua ucccuuauaa      720

augacaugcc uaucacaaac gaucaaaaaa aauuaauguc caacaacgua caaauaguaa      780

gacaacaauc auauuccauc augugcauca uaaaagaaga aguccucgca uacguagugc      840

aacuaccacu auacggaguc auagauacac ccuguuggaa acuucacaca ucuccacuau      900

gcacaacaaa cacgaaagaa ggauccaaca uaugccuaac acgaacagac agaggauggu      960

auugcgacaa cgcuggaagu gugagcuucu ucccucaagc agaaacuugc aaaguaugca     1020

gcaaucgugu auucugcgac acaaugaacu cauuaacacu cccaagcgaa guaaaccucu     1080

gcaauguaga caucuuuaau ccaaaauacg auuguaaaau aaugacuuca aaaacagacg     1140

ucucaucauc uguaauaaca ucuuuaggag caauaguuuc uugcuacggu aaaacaaaau     1200

gcaccgcauc caacaaaaac aaaggaauaa uaaaaacauu cucuaacggc ugcgauuacg     1260

uaucuaacaa aggaguugac acagucucag uaggaaacac acuauacuac guaaacaaac     1320

aagaaggaca aagccuauac guaaaaggag aaccaauaau aaacuucuau gacccauuag     1380

uauuuccaag cgaugaauuu gacgcuucaa uaucacaagu caaugaaaaa auaaaucaga     1440

gcuuagcauu cauaagaaaa ucugaugaac uacuacacaa uguaaaugca ggaaaaucca     1500

cuaccaacau aaugauuacc acaauuauaa uaguuaucau aguaauacua uuaucacuaa     1560

uagccguugg auuacuacua uacugcaaag caagauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6793
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6793
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacucauccu aaaagcaaac gccaucacca ccauacuaac cgccgucacc uucugcuucg      120

ccucgggaca aaacaucacc gaagaguucu accagucaac gugcuccgcc gucucaaaag      180

gcuaccuagg cgcccuccgc accggguggu auaccuccgu cauaacuauc gaacucucua      240

acaucaaaga aaacaaaugu aacggcaccg acgccaaagu caaacuaauc aaacaagaac      300

uggacaaaua caaaaacgcc gucaccgacc uacaaaugcu caugugcucc acuccagcca      360

ccggcuccgg uagcgcaauc gccucaggcg uagcuguaug caaaguccuc caccuagaag      420

gcgaaguaaa caaaauaaaa uccgcccucc ucucaaccaa caaggccguc gucucacucu      480

caaacggcgu cuccguacuc accuuuaaag uccuagaccu uaaaaacuac aucgacaaac      540

aacugcuacc aauccucaac aaacaaucau gcagcauccc aaacccggaa acagucaugg      600

aguuccaaca gaaaaacaac cgacuccucg aaaucacccg cgaguucucc gucaacgccg      660

gagucaccac accuguaagc acauacaugc uuacuaauuc cgaacuccuu ucacuaauaa      720

acgacaugcc aauaaccaac gaccaaaaga aacucauguc caacaacgua caaaucguac      780

gccaacaauc cuacuccauc augugcauca ucaaagaaga aguccuggcc uaugucguac      840

aacucccccu uuacgguguc aucgacacac ccugcuggaa acuacacacc agcccccucu      900

gcacaacaaa caccaaagaa ggcuccaaca ucugccucac ccguaccgac cgaggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaagc cgaaaccugc aaagucugca     1020

gcaaccgcgu cuucugcgau accaugaacu cccucacacu cccaucugaa gucaaccucu     1080

gcaacgucga uauuuucaau ccaaaauacg acugcaaaau caugacuagc aaaaccgacg     1140

uuagcuccuc cgucaucacc ucccucggcg ccauaguuuc augcuacggc aaaaccaaau     1200

gcaccgccuc caacaaaaac aaaggcauca uaaaaaccuu cuccaacggg ugcgacuacg     1260

uaucuaauaa aggagucgac accgucucag uaggaaacac ccucuacuau gucaacaaac     1320

aagaaggcca aucacuauac guuaaaggcg aaccaaucau caacuucuac gacccacucg     1380

ucuuccccag cgacgaguuu gacgccucaa ucucgcaagu caaugaaaag auuaaccaau     1440

cccuagccuu cauccgaaaa agugacgaac uccuccacaa cguuaacgcc ggcaaaucua     1500

caaccaacau caugaucacc acuauaauca ucgucaucau agucauacuu cucagccuca     1560

ucgcagucgg acuccuccuu uauugcaagg cacgauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  6794
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6794
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagaug      300

cugaugugcu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

cccaaccccg agacggugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugug cagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga acaaggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu acgugaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6795
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt1)

<400>  6795
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagaug      300

cucaugugca gcacccccgc caccgggucc ggcagcgcca ucgccuccgg cguggcggug      360

ugcaaggucc ugcaccugga gggggaggug aacaagauca agagcgcccu ccuguccacc      420

aacaaggccg uggucagccu guccaacggc gugagcgugc ucacguucaa gguccuggac      480

cugaagaacu acaucgacaa gcagcuccug ccgauccuga acaagcaguc cugcagcauc      540

cccaaccccg agaccgugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguucu ccgugaacgc cggggucacc acgcccguga gcaccuacau gcugaccaac      660

uccgagcucc ugagccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcugccc cucuacggcg ugaucgacac gcccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacacgaagg aggggagcaa caucugccuc      900

acccgcaccg accggggcug guacugcgac aacgcgggcu ccgugagcuu cuucccgcag      960

gccgagaccu gcaaggucug cuccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cugcccuccg aggucaaccu cugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg ggccaucgug     1140

uccugcuacg gcaagaccaa gugcaccgcc agcaacaaga acaaggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgucg acacgguguc cguggggaac     1260

acccuguacu acgucaacaa gcaggagggc cagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccuggcg uucauccgga aguccgacga gcuccugcac     1440

aacgugaacg ccggcaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc ugcucagccu gaucgccgug gggcugcucc uguacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6796
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt2)

<400>  6796
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagaug      300

cucaugugcu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

cccaaccccg agaccgucau ggaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucug cuccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga acaagggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu acgucaacaa gcaggagggc cagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6797
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt3)

<400>  6797
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga ccugcagaug      300

cuuauguguu ccacacccgc caccgggucu ggaucggcua uagcaucagg cguggccguc      360

ugcaaggugc ugcacuugga gggugagguu aacaaaauca agagcgcucu ccugaguacg      420

aauaaagccg uggucucccu gucuaacggg gugagcguac ucacuuuuaa gguuuuagau      480

cugaagaauu acauugacaa acagcuuuug ccuauccuga acaagcaauc cuguucaauu      540

ccaaauccgg aaaccgugau ggaguuccag cagaaaaaca auaggcuacu cgaaaucaca      600

cgggaguuua gugucaacgc gggagugacu acccccguga gcacauauau gcugaccaau      660

ucugagcuuc uguccuugau aaacgauaug ccuauuacga acgaccagaa gaaacucaug      720

ucaaauaacg uccaaaucgu ucgccagcag agcuacagua uuaugugcau caucaaggaa      780

gaggugcugg cauauguagu gcaguuacca cuguacggcg ucauugauac ucccuguugg      840

aaacuccaua caucuccucu uugcaccacu aauacaaagg aaggcuccaa cauaugucug      900

acccgaacgg accgugggug guacugcgau aaugccggaa gcgugucguu cuuuccacaa      960

gcugagaccu guaagguuug cucuaacaga guguucugcg acacaaugaa cuccuugacu     1020

cuacccucag aagucaaucu guguaaugug gauaucuuua acccuaaaua ugacugcaag     1080

auuaugacca guaaaacaga uguaagcucc ucuguuauca cuagccucgg ugccauagug     1140

ucauguuacg gcaagaccaa augcacagca aguaauaaga acaaggggau uaucaaaacc     1200

uucuccaaug gaugugacua ugucagcaac aagggcgugg acacugucuc uguggguaau     1260

acgcuguacu auguuaacaa acaggagggg cagucacuuu acgugaaggg agagccaauc     1320

auuaacuuuu augauccgcu gguauucccc agugacgaau uugaugcuag caucucccaa     1380

gucaaugaga aaauuaacca gucuuuggcc uucauaagga agucggacga acuccugcac     1440

aaugugaacg cgggcaagag cacaaccaau aucaugauua cuaccaucau cauuguuaua     1500

aucgugauuu uacugucccu aaucgccguc ggccuccugc uuuacugcaa agcacgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6798
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt4)

<400>  6798
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagaug      300

cugaugugca gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

cccaaccccg agaccgugau ggaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugug cagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acaagggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu acgugaacaa gcaggagggc cagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6799
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt5)

<400>  6799
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaauaaau gcaacgggac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga ccuccagaug      300

cugaugugua gcacccccgc cacaggaucc ggcucugcua uugccagcgg ggucgcggug      360

ugcaagguuc ugcaccucga gggagaggug aacaaaauca aguccgcccu gcuuagcacc      420

aauaaagcug ucgugucucu guccaacggc guuagcgugc ucacauuuaa gguccuggau      480

cuuaagaauu acauugacaa acagcugcuc ccuauccuga acaagcaauc uuguuccauu      540

ccgaaucccg aaaccgugau ggaguuccag cagaaaaaca aucggcugcu cgaaaucacg      600

cgcgaguuua gcgugaacgc cggcgucaca accccuguuu cuacauauau gcugaccaau      660

uccgagcuuc ugagccucau uaacgauaug cccaucacca acgaccagaa gaaacugaug      720

uccaauaacg ugcaaaucgu gagacagcag ucuuacagca uuaugugcau cauuaaggaa      780

gagguccuug cuuauguggu ucagcugccu cucuacgggg ugaucgauac acccuguugg      840

aaacugcaua cguccccucu gugcaccaca aauaccaagg aaggaagcaa cauuugucuc      900

acacggaccg accgcggcug guacugcgau aaugccgggu cugucuccuu cuuuccgcaa      960

gcggagacgu guaaggugug cagcaacaga guuuucugcg acacaaugaa cucucugacc     1020

cuucccagcg aagugaaucu guguaauguc gauaucuuua acccuaaaua ugacugcaag     1080

aucaugaccu ccaaaacaga ugugucuagc uccgucauua ccagccucgg agccaucgug     1140

ucuuguuacg gcaagacaaa augcacggcu uccaauaaga acaaggggau uaucaaaacc     1200

uucagcaaug gaugugacua uguuucuaac aagggcgugg acacagucuc cgugggcaau     1260

acccuguacu auguuaacaa acaggagggg cagagccuuu acgugaaggg agagcccauu     1320

aucaacuuuu augauccucu ggucuucccc uccgacgaau uugaugccuc uaucagccaa     1380

gugaaugaga aaauuaacca gucccucgcu uucauccgga agucugacga acugcugcac     1440

aaugugaacg ccggcaagag cacaaccaau auuaugauca cgaccauuau cauuguuauc     1500

aucgucauuc uccugucccu uaucgccgug gggcugcucc uguacugcaa agcucgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6800
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt6)

<400>  6800
gggagaaagc uuaccaugga acuacucaua uuaaaagcaa acgcaauaac aacgauauua       60

acagcuguaa cauucugcuu ugcaucaggc caaaauauca ccgaagaauu uuaucaaagc      120

acaugcucug caguauccaa aggauacuua ggagcauuaa gaacaggcug guacacaucc      180

guaauaacaa uagaacuauc aaacaucaaa gaaaacaaau gcaacggcac agacgccaaa      240

guaaaacuca uaaaacaaga acuagacaaa uauaaaaacg caguaacaga ucuacaaaug      300

cucaugugcu ccacaccagc aaccggaucu gguucagcca uagcauccgg cguagccguc      360

ugcaaaguau uacaccucga aggagaagua aacaaaauaa aaucugcccu auuaucuaca      420

aauaaagccg uaguaagucu aaguaacgga guaucaguac uaacauuuaa aguccuagac      480

cugaaaaacu auaucgacaa acaacuauua ccaauacuaa acaaacaauc cuguuccauc      540

ccuaacccag aaacaguuau ggaauuucaa caaaaaaaua accgccuuuu agaaauaacu      600

agagaauuuu caguaaacgc aggaguuaca acaccaguau caacauacau gcuaacaaau      660

ucagaauuau uaucccuuau aaaugacaug ccuaucacaa acgaucaaaa aaaauuaaug      720

uccaacaacg uacaaauagu aagacaacaa ucauauucca ucaugugcau cauaaaagaa      780

gaaguccucg cauacguagu gcaacuacca cuauacggag ucauagauac acccuguugg      840

aaacuucaca caucuccacu augcacaaca aacacgaaag aaggauccaa cauaugccua      900

acacgaacag acagaggaug guauugcgac aacgcuggaa gugugagcuu cuucccucaa      960

gcagaaacuu gcaaaguaug cagcaaucgu guauucugcg acacaaugaa cucauuaaca     1020

cucccaagcg aaguaaaccu cugcaaugua gacaucuuua auccaaaaua cgauuguaaa     1080

auaaugacuu caaaaacaga cgucucauca ucuguaauaa caucuuuagg agcaauaguu     1140

ucuugcuacg guaaaacaaa augcaccgca uccaacaaaa acaaaggaau aauaaaaaca     1200

uucucuaacg gcugcgauua cguaucuaac aaaggaguug acacagucuc aguaggaaac     1260

acacuauacu acguaaacaa acaagaagga caaagccuau acguaaaagg agaaccaaua     1320

auaaacuucu augacccauu aguauuucca agcgaugaau uugacgcuuc aauaucacaa     1380

gucaaugaaa aaauaaauca gagcuuagca uucauaagaa aaucugauga acuacuacac     1440

aauguaaaug caggaaaauc cacuaccaac auaaugauua ccacaauuau aauaguuauc     1500

auaguaauac uauuaucacu aauagccguu ggauuacuac uauacugcaa agcaagauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6801
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut6 (opt11)

<400>  6801
gggagaaagc uuaccaugga acuacucauc cuaaaagcaa acgccaucac caccauacua       60

accgccguca ccuucugcuu cgccucggga caaaacauca ccgaagaguu cuaccaguca      120

acgugcuccg ccgucucaaa aggcuaccua ggcgcccucc gcaccgggug guauaccucc      180

gucauaacua ucgaacucuc uaacaucaaa gaaaacaaau guaacggcac cgacgccaaa      240

gucaaacuaa ucaaacaaga acuggacaaa uacaaaaacg ccgucaccga ccuacaaaug      300

cucaugugcu ccacuccagc caccggcucc gguagcgcaa ucgccucagg cguagcugua      360

ugcaaagucc uccaccuaga aggcgaagua aacaaaauaa aauccgcccu ccucucaacc      420

aacaaggccg ucgucucacu cucaaacggc gucuccguac ucaccuuuaa aguccuagac      480

cuuaaaaacu acaucgacaa acaacugcua ccaauccuca acaaacaauc augcagcauc      540

ccaaacccgg aaacagucau ggaguuccaa cagaaaaaca accgacuccu cgaaaucacc      600

cgcgaguucu ccgucaacgc cggagucacc acaccuguaa gcacauacau gcuuacuaau      660

uccgaacucc uuucacuaau aaacgacaug ccaauaacca acgaccaaaa gaaacucaug      720

uccaacaacg uacaaaucgu acgccaacaa uccuacucca ucaugugcau caucaaagaa      780

gaaguccugg ccuaugucgu acaacucccc cuuuacggug ucaucgacac acccugcugg      840

aaacuacaca ccagcccccu cugcacaaca aacaccaaag aaggcuccaa caucugccuc      900

acccguaccg accgaggcug guacugcgac aacgccggcu ccgucuccuu cuucccccaa      960

gccgaaaccu gcaaagucug cagcaaccgc gucuucugcg auaccaugaa cucccucaca     1020

cucccaucug aagucaaccu cugcaacguc gauauuuuca auccaaaaua cgacugcaaa     1080

aucaugacua gcaaaaccga cguuagcucc uccgucauca ccucccucgg cgccauaguu     1140

ucaugcuacg gcaaaaccaa augcaccgcc uccaacaaaa acaaaggcau cauaaaaacc     1200

uucuccaacg ggugcgacua cguaucuaau aaaggagucg acaccgucuc aguaggaaac     1260

acccucuacu augucaacaa acaagaaggc caaucacuau acguuaaagg cgaaccaauc     1320

aucaacuucu acgacccacu cgucuucccc agcgacgagu uugacgccuc aaucucgcaa     1380

gucaaugaaa agauuaacca aucccuagcc uucauccgaa aaagugacga acuccuccac     1440

aacguuaacg ccggcaaauc uacaaccaac aucaugauca ccacuauaau caucgucauc     1500

auagucauac uucucagccu caucgcaguc ggacuccucc uuuauugcaa ggcacgauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  6802
<211>  535
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6802

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Met Leu 
                85                  90                  95      


Met Cys Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Ser 
                165                 170                 175     


Asn Ile Glu Thr Val Met Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Cys Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Lys Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Tyr Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly Ile 
        515                 520                 525             


Asn Asn Ile Ala Phe Ser Asn 
    530                 535 


<210>  6803
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6803
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agaugcugau gugcuccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugugcagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaacaag gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1560

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacuga                  1608


<210>  6804
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6804
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agaugcucau gugcuccacc      300

cccgccaccg gcagcggguc cgccaucgcc agcggcgugg cggugugcaa gguccugcac      360

cuggagggcg aggugaacaa gaucaagucc gcccuccuga gcaccaacaa ggccgugguc      420

ucccugagca acgggguguc cgugcucacg uucaaggucc uggaccugaa gaacuacauc      480

gacaagcagc uccugccgau ccugaacaag cagagcugcu ccaucagcaa caucgagacc      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucuccgug      600

aacgccggcg ucaccacgcc cgugagcacc uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ugccccucua cggggugauc gacacgccgu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac gaaggagggc agcaacaucu gccucacccg caccgaccgg      900

gggugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag      960

gucugcucca accgcguguu cugcgacacg augaacagcc ugacccugcc cuccgagguc     1020

aaccucugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1140

accaagugca ccgccagcaa caagaacaag ggcaucauca agaccuucuc caacgggugc     1200

gacuacguga gcaacaaggg cgucgacacg gugagcgugg gcaacacccu guacuacguc     1260

aacaagcagg aggggaaguc ccucuacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc uggcguucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggg     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccugcuc     1500

agccugaucg ccgugggccu gcuccuguac ugcaaggccc gcuccacccc ggugacccug     1560

agcaaggacc agcuguccgg gaucaacaac aucgccuuca gcaacuga                  1608


<210>  6805
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6805
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agaugcucau gugcuccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      540

gucauggagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

gucugcucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaacaag ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1260

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1560

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacuga                  1608


<210>  6806
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6806
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agaugcuuau guguucuaca      300

cccgccaccg gcucgggguc agcuauagca agcggagugg ccgucugcaa ggugcugcac      360

uuggagggcg aaguuaacaa aaucaagagu gcucuccugu ccacgaauaa agccgugguc      420

ucucugagca acgguguguc cguacucacu uuuaagguuu uagaccugaa gaauuacauu      480

gauaaacagc uuuugccuau ccugaacaag caaucaugua guauuagcaa uaucgagacc      540

gugauggagu uccagcagaa aaacaauagg cuacucgaaa uaacacggga guuuucuguc      600

aacgcggggg ugacuacccc aguguccaca uauaugcuga ccaauucaga acuucugagc      660

uugauuaacg acaugccgau cacgaacgau cagaagaaac ucaugaguaa uaacguccaa      720

auuguucgcc agcagucuua cuccaucaug ugcaucauua aggaggaagu gcuggcauau      780

guagugcagu uaccccugua cggagucaua gacacuccuu guuggaaacu ccauacaagc      840

ccacuuugca ccacuaauac aaaggagggc ucgaacaucu gucugacccg aacggaucgu      900

ggcugguacu gcgacaaugc cgggucugug uccuucuuuc cccaagcuga aaccuguaag      960

guuugcucaa acagaguguu cugcgauaca augaauaguu ugacucuacc uagcgagguc     1020

aaccugugua auguggacau uuuuaaccca aaauaugauu gcaagaucau gaccuccaaa     1080

acagacguau cuagcucagu uauaacuagc cucggagcca uuguguccug uuacgguaag     1140

accaaaugca cagcaagcaa uaagaacaag ggcaucauca aaaccuucuc uaaugggugu     1200

gauuaugucu caaacaaggg aguggacacu gucagugugg gcaauacgcu guacuauguu     1260

aacaaacagg aggguaagag ccuuuacgug aaaggggaac ccauuaucaa cuuuuaugac     1320

ccucugguau ucccauccga ugaguuugac gcuucuauuu cgcaggucaa ugaaaagaua     1380

aaccaaaguu uggccuucau caggaagucc gaugagcucc ugcacaaugu gaacgcggga     1440

aaaucaacaa ccaauauuau gaucacuacc aucauuauag uuaucauugu gaucuuacug     1500

agucuaauug ccgucggccu ccugcuuuac ugcaaggcac ggucuacacc ggugaccuug     1560

agcaaagacc agcuguccgg caucaacaau auagcuuucu caaacuga                  1608


<210>  6807
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6807
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agaugcugau gugcagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      540

gugauggagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugugcagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaag ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1560

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacuga                  1608


<210>  6808
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6808
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agaugcugau guguuccacc      300

cccgccacag ggucuggaag cgcuauugcc uccggcgucg cggugugcaa gguucugcac      360

cucgaggggg aagugaacaa aaucaagagc gcccugcuuu cuaccaauaa agcugucgug      420

ucccugagca acggaguuuc ugugcucaca uuuaaggucc uggaccuuaa gaauuacauu      480

gauaaacagc ugcucccuau ccugaacaag caauccugua gcauuucuaa uaucgagacc      540

gugauggagu uccagcagaa aaacaaucgg cugcucgaaa uuacgcgcga guuuuccgug      600

aacgccggcg ucacaacccc gguuagcaca uauaugcuga ccaauuccga acuucugucu      660

cucaucaacg acaugcccau caccaacgau cagaagaaac ugaugagcaa uaacgugcaa      720

auugugagac agcaguccua cagcaucaug ugcauuauca aggaggaagu ccuugcuuau      780

gugguucagc ugccucucua cggcgugauu gacacacccu guuggaaacu gcauacgucu      840

ccucugugca ccacaaauac caaggagggg uccaacaucu gucucacacg gaccgaucgc      900

ggaugguacu gcgacaaugc cggcagcguc ucuuucuuuc cccaagcgga aacguguaag      960

gugugcagca acagaguuuu cugcgauaca augaacuccc ugacccuucc uucugaggug     1020

aaucugugua augucgacau cuuuaacccg aaauaugauu gcaagauuau gaccagcaaa     1080

acagacgugu ccagcucugu caucaccucc cucggggcca uugugagcug uuacggaaag     1140

acaaaaugca cggcuucuaa uaagaacaag ggcaucauua aaaccuucuc caaugggugu     1200

gauuauguua gcaacaaggg aguggacaca gucuccgugg gcaauacccu guacuauguu     1260

aacaaacagg agggcaaguc ucuuuacgug aaaggggaac ccaucaucaa cuuuuaugac     1320

ccucuggucu uccccagcga ugaguuugac gccuccauuu cucaggugaa ugaaaagauc     1380

aaccaaagcc ucgcuuucau ucggaagucc gaugagcugc ugcacaaugu gaacgccgga     1440

aaaagcacaa ccaauaucau gauuacgacc aucauuaucg uuaucauugu cauccuccug     1500

ucucuuauug ccgugggccu gcuccuguac ugcaaggcuc gcuccacacc ugugacccug     1560

agcaaagacc agcuuucugg gaucaacaau auugcguucu ccaacuga                  1608


<210>  6809
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6809
auggaauuac ucauacucaa agcaaaugca auuaccacua uacucacagc uguaacuuuu       60

uguuucgccu caggacaaaa caucacagaa gaauuuuauc aauccacaug cucugccgua      120

ucaaaaggcu accuaucugc ccuaagaaca gguugguaca caucuguaau aacaaucgaa      180

uuauccaaca ucaaagaaaa caaaugcaac ggcacagacg caaaagucaa acucaucaaa      240

caagaauuag auaaauauaa aaacgcagua acagaacuac aaaugcuaau gugcucuaca      300

cccgccacag gaucaggauc cgcaaucgcu ucuggaguag ccguuugcaa aguauuacac      360

cuagaaggag aaguaaauaa aauaaaaucc gcacuacuau caacuaauaa agcaguagua      420

ucacuuucua augguguauc aguauuaaca uucaaagucc ucgaccuaaa aaauuacauc      480

gacaaacaac uauuacccau ccuuaauaaa caaucaugcu ccauaucaaa cauagaaacu      540

gucauggaau uucaacaaaa aaacaauaga cuucuagaaa ucacaagaga auuuucugua      600

aaugcaggag uaacuacacc aguaucaaca uauauguuaa ccaacuccga acuacuauca      660

cucauaaacg acaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguucaa      720

auaguaagac aacaaucaua cucaaucaug ugcauaauaa aagaagaagu uuuagcauac      780

gucguacaac uuccccuaua cggaguaaua gacaccccuu gcuggaaacu ccacaccuca      840

ccacuaugca cuacaaacac aaaagaaggu uccaacaucu gcuuaacaag aaccgaucga      900

ggaugguacu gcgacaacgc ugguuccgua ucuuucuucc cacaagcaga aacaugcaaa      960

guaugcucca auagaguauu cugcgacacc augaacucac uaacucuacc auccgaagua     1020

aaccuaugca acgucgacau auuuaaucca aaauaugacu gcaaaauaau gacuucaaaa     1080

acagacguau ccucaucagu aauaacaucc uuaggagcaa uaguaucaug uuacggcaag     1140

acaaaaugua cagccucaaa caaaaacaaa gguaucauua aaaccuucuc caacggcugc     1200

gacuacguau caaauaaagg ugucgauaca guaucaguag gaaacacacu cuauuacguu     1260

aauaaacaag aaggaaaguc auuauacgua aaaggagaac caauaaucaa uuucuacgau     1320

ccccuagucu uucccucaga ugaauuugac gcaagcaucu cucaagucaa cgaaaaaaua     1380

aaccaauccc uagccuucau aagaaaauca gaugaacuac uucauaacgu caacgccgga     1440

aaaucaacaa ccaacauaau gaucacuaca aucauaauug uaauuauagu aauacuacua     1500

ucgcuaauug ccguuggacu acuacuauau uguaaagcaa gaucaacacc cguuacucua     1560

uccaaagauc aauuaucagg aaucaacaac auagccuucu caaauuaa                  1608


<210>  6810
<211>  1608
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut7

<400>  6810
auggaacuac ucauacuuaa agccaacgca auaaccacaa uccucaccgc cgucacauuc       60

ugcuucgccu cgggacaaaa cauaaccgaa gaauuuuacc agucuaccug cuccgccguc      120

uccaaggguu accucuccgc gcuccgcacc gggugguaca ccagcguuau caccaucgaa      180

cuaucuaaca uaaaagaaaa caagugcaac ggaaccgacg caaaagucaa acucaucaaa      240

caagaacuag acaaauacaa gaaugccguc accgaacuac aaaugcucau gugcuccacc      300

cccgccaccg gauccggcuc cgccauugcc uccggcgucg ccguaugcaa aguccuucac      360

uuggaaggag aaguuaacaa aauaaaaagc gcccuccugu cgaccaacaa agcggugguc      420

agccucucca acggcgucuc uguccucacc uucaaagucc ucgaccucaa gaacuacaua      480

gauaaacaac uacuccccau ccuaaacaaa cagucaugca gcauauccaa caucgaaacc      540

gucauggagu uccaacagaa aaacaaccgc cuccuugaaa ucacccgcga guucucuguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca caaacuccga acuccucagc      660

cucaucaacg acaugccaau caccaacgac caaaagaaac ucauguccaa caacguacaa      720

aucguucguc aacaaucaua cucaaucaug ugcaucauua aagaagaagu ccucgcauac      780

gucguccaac ucccccucua uggggucauc gacaccccau gcuggaaacu ccacaccucu      840

ccccuaugca ccaccaacac caaagaaggc uccaacaucu gccuaacccg aaccgaccgc      900

ggaugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga aacauguaaa      960

gucugcucca accguguguu cugcgacacc augaacucac uaacccuccc cuccgaaguc     1020

aaccucugca acgucgacau cuucaacccg aaauacgacu gcaaaauaau gaccagcaaa     1080

acagacguau ccucuagcgu cauuaccagc cuaggugcaa ucguguccug cuacggcaaa     1140

acaaaaugca ccgccuccaa caaaaauaaa ggaaucauaa aaaccuucuc caacggcugc     1200

gacuacguca gcaacaaagg agucgacacc gucuccguag gaaauacucu auacuauguc     1260

aacaaacaag aggguaaauc ccucuacguc aaaggcgaac ccaucaucaa cuucuacgac     1320

ccccucgucu uccccucuga cgaguucgac gccagcauau cacaaguaaa cgaaaagauc     1380

aaccaauccc ucgcauucau ucgcaaaucc gacgaacucc uacacaacgu caacgccgga     1440

aaauccacca ccaacaucau gaucacuacu aucauuaucg ucaucaucgu cauccuccuc     1500

ucccucaucg cagucggccu ucuacucuac ugcaaggcac gcucuacacc cguaacccug     1560

ucuaaagacc aacucuccgg caucaacaac aucgcuuucu ccaacuaa                  1608


<210>  6811
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6811
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6812
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6812
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

ccaccccggu gacccugagc aaggaccagc uguccgggau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6813
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6813
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6814
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6814
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

cuacaccggu gaccuugagc aaagaccagc uguccggcau caacaauaua gcuuucucaa     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6815
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6815
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6816
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6816
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

ccacaccugu gacccugagc aaagaccagc uuucugggau caacaauauu gcguucucca     1680

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6817
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6817
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacucaaagc aaaugcaauu accacuauac      120

ucacagcugu aacuuuuugu uucgccucag gacaaaacau cacagaagaa uuuuaucaau      180

ccacaugcuc ugccguauca aaaggcuacc uaucugcccu aagaacaggu ugguacacau      240

cuguaauaac aaucgaauua uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaaacaa gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa      360

ugcuaaugug cucuacaccc gccacaggau caggauccgc aaucgcuucu ggaguagccg      420

uuugcaaagu auuacaccua gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa      480

cuaauaaagc aguaguauca cuuucuaaug guguaucagu auuaacauuc aaaguccucg      540

accuaaaaaa uuacaucgac aaacaacuau uacccauccu uaauaaacaa ucaugcucca      600

uaucaaacau agaaacuguc auggaauuuc aacaaaaaaa caauagacuu cuagaaauca      660

caagagaauu uucuguaaau gcaggaguaa cuacaccagu aucaacauau auguuaacca      720

acuccgaacu acuaucacuc auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa      780

ugucaaauaa cguucaaaua guaagacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguuuu agcauacguc guacaacuuc cccuauacgg aguaauagac accccuugcu      900

ggaaacucca caccucacca cuaugcacua caaacacaaa agaagguucc aacaucugcu      960

uaacaagaac cgaucgagga ugguacugcg acaacgcugg uuccguaucu uucuucccac     1020

aagcagaaac augcaaagua ugcuccaaua gaguauucug cgacaccaug aacucacuaa     1080

cucuaccauc cgaaguaaac cuaugcaacg ucgacauauu uaauccaaaa uaugacugca     1140

aaauaaugac uucaaaaaca gacguauccu caucaguaau aacauccuua ggagcaauag     1200

uaucauguua cggcaagaca aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa     1260

ccuucuccaa cggcugcgac uacguaucaa auaaaggugu cgauacagua ucaguaggaa     1320

acacacucua uuacguuaau aaacaagaag gaaagucauu auacguaaaa ggagaaccaa     1380

uaaucaauuu cuacgauccc cuagucuuuc ccucagauga auuugacgca agcaucucuc     1440

aagucaacga aaaaauaaac caaucccuag ccuucauaag aaaaucagau gaacuacuuc     1500

auaacgucaa cgccggaaaa ucaacaacca acauaaugau cacuacaauc auaauuguaa     1560

uuauaguaau acuacuaucg cuaauugccg uuggacuacu acuauauugu aaagcaagau     1620

caacacccgu uacucuaucc aaagaucaau uaucaggaau caacaacaua gccuucucaa     1680

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6818
<211>  1884
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6818
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuuaaagc caacgcaaua accacaaucc      120

ucaccgccgu cacauucugc uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu      180

cuaccugcuc cgccgucucc aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca      240

gcguuaucac caucgaacua ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaagaa ugccgucacc gaacuacaaa      360

ugcucaugug cuccaccccc gccaccggau ccggcuccgc cauugccucc ggcgucgccg      420

uaugcaaagu ccuucacuug gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga      480

ccaacaaagc gguggucagc cucuccaacg gcgucucugu ccucaccuuc aaaguccucg      540

accucaagaa cuacauagau aaacaacuac uccccauccu aaacaaacag ucaugcagca      600

uauccaacau cgaaaccguc auggaguucc aacagaaaaa caaccgccuc cuugaaauca      660

cccgcgaguu cucugucaac gccggcguca ccacccccgu cuccaccuac augcucacaa      720

acuccgaacu ccucagccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgucaac aaucauacuc aaucaugugc aucauuaaag      840

aagaaguccu cgcauacguc guccaacucc cccucuaugg ggucaucgac accccaugcu      900

ggaaacucca caccucuccc cuaugcacca ccaacaccaa agaaggcucc aacaucugcc      960

uaacccgaac cgaccgcgga ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgaaac auguaaaguc ugcuccaacc guguguucug cgacaccaug aacucacuaa     1080

cccuccccuc cgaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaauaaugac cagcaaaaca gacguauccu cuagcgucau uaccagccua ggugcaaucg     1200

uguccugcua cggcaaaaca aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa     1260

ccuucuccaa cggcugcgac uacgucagca acaaaggagu cgacaccguc uccguaggaa     1320

auacucuaua cuaugucaac aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccucugacga guucgacgcc agcauaucac     1440

aaguaaacga aaagaucaac caaucccucg cauucauucg caaauccgac gaacuccuac     1500

acaacgucaa cgccggaaaa uccaccacca acaucaugau cacuacuauc auuaucguca     1560

ucaucgucau ccuccucucc cucaucgcag ucggccuucu acucuacugc aaggcacgcu     1620

cuacacccgu aacccugucu aaagaccaac ucuccggcau caacaacauc gcuuucucca     1680

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1740

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1860

gcucuuuuca gagccaccag aauu                                            1884


<210>  6819
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6819
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6820
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6820
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcuc caccccggug acccugagca aggaccagcu guccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6821
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6821
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6822
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6822
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacgguc uacaccggug accuugagca aagaccagcu guccggcauc     1680

aacaauauag cuuucucaaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6823
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6823
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6824
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6824
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcuc cacaccugug acccugagca aagaccagcu uucugggauc     1680

aacaauauug cguucuccaa cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6825
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6825
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acucaaagca      120

aaugcaauua ccacuauacu cacagcugua acuuuuuguu ucgccucagg acaaaacauc      180

acagaagaau uuuaucaauc cacaugcucu gccguaucaa aaggcuaccu aucugcccua      240

agaacagguu gguacacauc uguaauaaca aucgaauuau ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaaacaag aauuagauaa auauaaaaac      360

gcaguaacag aacuacaaau gcuaaugugc ucuacacccg ccacaggauc aggauccgca      420

aucgcuucug gaguagccgu uugcaaagua uuacaccuag aaggagaagu aaauaaaaua      480

aaauccgcac uacuaucaac uaauaaagca guaguaucac uuucuaaugg uguaucagua      540

uuaacauuca aaguccucga ccuaaaaaau uacaucgaca aacaacuauu acccauccuu      600

aauaaacaau caugcuccau aucaaacaua gaaacuguca uggaauuuca acaaaaaaac      660

aauagacuuc uagaaaucac aagagaauuu ucuguaaaug caggaguaac uacaccagua      720

ucaacauaua uguuaaccaa cuccgaacua cuaucacuca uaaacgacau gccaauaaca      780

aacgaccaaa aaaaacuaau gucaaauaac guucaaauag uaagacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguuuua gcauacgucg uacaacuucc ccuauacgga      900

guaauagaca ccccuugcug gaaacuccac accucaccac uaugcacuac aaacacaaaa      960

gaagguucca acaucugcuu aacaagaacc gaucgaggau gguacugcga caacgcuggu     1020

uccguaucuu ucuucccaca agcagaaaca ugcaaaguau gcuccaauag aguauucugc     1080

gacaccauga acucacuaac ucuaccaucc gaaguaaacc uaugcaacgu cgacauauuu     1140

aauccaaaau augacugcaa aauaaugacu ucaaaaacag acguauccuc aucaguaaua     1200

acauccuuag gagcaauagu aucauguuac ggcaagacaa aauguacagc cucaaacaaa     1260

aacaaaggua ucauuaaaac cuucuccaac ggcugcgacu acguaucaaa uaaagguguc     1320

gauacaguau caguaggaaa cacacucuau uacguuaaua aacaagaagg aaagucauua     1380

uacguaaaag gagaaccaau aaucaauuuc uacgaucccc uagucuuucc cucagaugaa     1440

uuugacgcaa gcaucucuca agucaacgaa aaaauaaacc aaucccuagc cuucauaaga     1500

aaaucagaug aacuacuuca uaacgucaac gccggaaaau caacaaccaa cauaaugauc     1560

acuacaauca uaauuguaau uauaguaaua cuacuaucgc uaauugccgu uggacuacua     1620

cuauauugua aagcaagauc aacacccguu acucuaucca aagaucaauu aucaggaauc     1680

aacaacauag ccuucucaaa uuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6826
<211>  1903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6826
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuuaaagcc      120

aacgcaauaa ccacaauccu caccgccguc acauucugcu ucgccucggg acaaaacaua      180

accgaagaau uuuaccaguc uaccugcucc gccgucucca aggguuaccu cuccgcgcuc      240

cgcaccgggu gguacaccag cguuaucacc aucgaacuau cuaacauaaa agaaaacaag      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaagaau      360

gccgucaccg aacuacaaau gcucaugugc uccacccccg ccaccggauc cggcuccgcc      420

auugccuccg gcgucgccgu augcaaaguc cuucacuugg aaggagaagu uaacaaaaua      480

aaaagcgccc uccugucgac caacaaagcg guggucagcc ucuccaacgg cgucucuguc      540

cucaccuuca aaguccucga ccucaagaac uacauagaua aacaacuacu ccccauccua      600

aacaaacagu caugcagcau auccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaccgccucc uugaaaucac ccgcgaguuc ucugucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucacaaa cuccgaacuc cucagccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgucaaca aucauacuca      840

aucaugugca ucauuaaaga agaaguccuc gcauacgucg uccaacuccc ccucuauggg      900

gucaucgaca ccccaugcug gaaacuccac accucucccc uaugcaccac caacaccaaa      960

gaaggcucca acaucugccu aacccgaacc gaccgcggau gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgaaaca uguaaagucu gcuccaaccg uguguucugc     1080

gacaccauga acucacuaac ccuccccucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aauaaugacc agcaaaacag acguauccuc uagcgucauu     1200

accagccuag gugcaaucgu guccugcuac ggcaaaacaa aaugcaccgc cuccaacaaa     1260

aauaaaggaa ucauaaaaac cuucuccaac ggcugcgacu acgucagcaa caaaggaguc     1320

gacaccgucu ccguaggaaa uacucuauac uaugucaaca aacaagaggg uaaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cucugacgag     1440

uucgacgcca gcauaucaca aguaaacgaa aagaucaacc aaucccucgc auucauucgc     1500

aaauccgacg aacuccuaca caacgucaac gccggaaaau ccaccaccaa caucaugauc     1560

acuacuauca uuaucgucau caucgucauc cuccucuccc ucaucgcagu cggccuucua     1620

cucuacugca aggcacgcuc uacacccgua acccugucua aagaccaacu cuccggcauc     1680

aacaacaucg cuuucuccaa cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1740

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1860

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1903


<210>  6827
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6827
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6828
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6828
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcucca ccccggugac ccugagcaag     1740

gaccagcugu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6829
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6829
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6830
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6830
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggucua caccggugac cuugagcaaa     1740

gaccagcugu ccggcaucaa caauauagcu uucucaaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6831
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6831
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6832
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6832
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcucca caccugugac ccugagcaaa     1740

gaccagcuuu cugggaucaa caauauugcg uucuccaacu gaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6833
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6833
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac ucaaagcaaa ugcaauuacc acuauacuca cagcuguaac uuuuuguuuc      240

gccucaggac aaaacaucac agaagaauuu uaucaaucca caugcucugc cguaucaaaa      300

ggcuaccuau cugcccuaag aacagguugg uacacaucug uaauaacaau cgaauuaucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caaacaagaa      420

uuagauaaau auaaaaacgc aguaacagaa cuacaaaugc uaaugugcuc uacacccgcc      480

acaggaucag gauccgcaau cgcuucugga guagccguuu gcaaaguauu acaccuagaa      540

ggagaaguaa auaaaauaaa auccgcacua cuaucaacua auaaagcagu aguaucacuu      600

ucuaauggug uaucaguauu aacauucaaa guccucgacc uaaaaaauua caucgacaaa      660

caacuauuac ccauccuuaa uaaacaauca ugcuccauau caaacauaga aacugucaug      720

gaauuucaac aaaaaaacaa uagacuucua gaaaucacaa gagaauuuuc uguaaaugca      780

ggaguaacua caccaguauc aacauauaug uuaaccaacu ccgaacuacu aucacucaua      840

aacgacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu ucaaauagua      900

agacaacaau cauacucaau caugugcaua auaaaagaag aaguuuuagc auacgucgua      960

caacuucccc uauacggagu aauagacacc ccuugcugga aacuccacac cucaccacua     1020

ugcacuacaa acacaaaaga agguuccaac aucugcuuaa caagaaccga ucgaggaugg     1080

uacugcgaca acgcugguuc cguaucuuuc uucccacaag cagaaacaug caaaguaugc     1140

uccaauagag uauucugcga caccaugaac ucacuaacuc uaccauccga aguaaaccua     1200

ugcaacgucg acauauuuaa uccaaaauau gacugcaaaa uaaugacuuc aaaaacagac     1260

guauccucau caguaauaac auccuuagga gcaauaguau cauguuacgg caagacaaaa     1320

uguacagccu caaacaaaaa caaagguauc auuaaaaccu ucuccaacgg cugcgacuac     1380

guaucaaaua aaggugucga uacaguauca guaggaaaca cacucuauua cguuaauaaa     1440

caagaaggaa agucauuaua cguaaaagga gaaccaauaa ucaauuucua cgauccccua     1500

gucuuucccu cagaugaauu ugacgcaagc aucucucaag ucaacgaaaa aauaaaccaa     1560

ucccuagccu ucauaagaaa aucagaugaa cuacuucaua acgucaacgc cggaaaauca     1620

acaaccaaca uaaugaucac uacaaucaua auuguaauua uaguaauacu acuaucgcua     1680

auugccguug gacuacuacu auauuguaaa gcaagaucaa cacccguuac ucuauccaaa     1740

gaucaauuau caggaaucaa caacauagcc uucucaaauu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6834
<211>  1981
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6834
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uuaaagccaa cgcaauaacc acaauccuca ccgccgucac auucugcuuc      240

gccucgggac aaaacauaac cgaagaauuu uaccagucua ccugcuccgc cgucuccaag      300

gguuaccucu ccgcgcuccg caccgggugg uacaccagcg uuaucaccau cgaacuaucu      360

aacauaaaag aaaacaagug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaagaaugc cgucaccgaa cuacaaaugc ucaugugcuc cacccccgcc      480

accggauccg gcuccgccau ugccuccggc gucgccguau gcaaaguccu ucacuuggaa      540

ggagaaguua acaaaauaaa aagcgcccuc cugucgacca acaaagcggu ggucagccuc      600

uccaacggcg ucucuguccu caccuucaaa guccucgacc ucaagaacua cauagauaaa      660

caacuacucc ccauccuaaa caaacaguca ugcagcauau ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ccgccuccuu gaaaucaccc gcgaguucuc ugucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucacaaacu ccgaacuccu cagccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgucaacaau cauacucaau caugugcauc auuaaagaag aaguccucgc auacgucguc      960

caacuccccc ucuauggggu caucgacacc ccaugcugga aacuccacac cucuccccua     1020

ugcaccacca acaccaaaga aggcuccaac aucugccuaa cccgaaccga ccgcggaugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgaaacaug uaaagucugc     1140

uccaaccgug uguucugcga caccaugaac ucacuaaccc uccccuccga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa uaaugaccag caaaacagac     1260

guauccucua gcgucauuac cagccuaggu gcaaucgugu ccugcuacgg caaaacaaaa     1320

ugcaccgccu ccaacaaaaa uaaaggaauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucagcaaca aaggagucga caccgucucc guaggaaaua cucuauacua ugucaacaaa     1440

caagagggua aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu cugacgaguu cgacgccagc auaucacaag uaaacgaaaa gaucaaccaa     1560

ucccucgcau ucauucgcaa auccgacgaa cuccuacaca acgucaacgc cggaaaaucc     1620

accaccaaca ucaugaucac uacuaucauu aucgucauca ucgucauccu ccucucccuc     1680

aucgcagucg gccuucuacu cuacugcaag gcacgcucua cacccguaac ccugucuaaa     1740

gaccaacucu ccggcaucaa caacaucgcu uucuccaacu aaggacuagu cccuguuccc     1800

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1920

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1980

u                                                                     1981


<210>  6835
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6835
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6836
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6836
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcuccac cccggugacc     1680

cugagcaagg accagcuguc cgggaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6837
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6837
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6838
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6838
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggucuac accggugacc     1680

uugagcaaag accagcuguc cggcaucaac aauauagcuu ucucaaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6839
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6839
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6840
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6840
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcuccac accugugacc     1680

cugagcaaag accagcuuuc ugggaucaac aauauugcgu ucuccaacug aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6841
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6841
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu caaagcaaau gcaauuacca cuauacucac agcuguaacu      180

uuuuguuucg ccucaggaca aaacaucaca gaagaauuuu aucaauccac augcucugcc      240

guaucaaaag gcuaccuauc ugcccuaaga acagguuggu acacaucugu aauaacaauc      300

gaauuaucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aaacaagaau uagauaaaua uaaaaacgca guaacagaac uacaaaugcu aaugugcucu      420

acacccgcca caggaucagg auccgcaauc gcuucuggag uagccguuug caaaguauua      480

caccuagaag gagaaguaaa uaaaauaaaa uccgcacuac uaucaacuaa uaaagcagua      540

guaucacuuu cuaauggugu aucaguauua acauucaaag uccucgaccu aaaaaauuac      600

aucgacaaac aacuauuacc cauccuuaau aaacaaucau gcuccauauc aaacauagaa      660

acugucaugg aauuucaaca aaaaaacaau agacuucuag aaaucacaag agaauuuucu      720

guaaaugcag gaguaacuac accaguauca acauauaugu uaaccaacuc cgaacuacua      780

ucacucauaa acgacaugcc aauaacaaac gaccaaaaaa aacuaauguc aaauaacguu      840

caaauaguaa gacaacaauc auacucaauc augugcauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuuccccu auacggagua auagacaccc cuugcuggaa acuccacacc      960

ucaccacuau gcacuacaaa cacaaaagaa gguuccaaca ucugcuuaac aagaaccgau     1020

cgaggauggu acugcgacaa cgcugguucc guaucuuucu ucccacaagc agaaacaugc     1080

aaaguaugcu ccaauagagu auucugcgac accaugaacu cacuaacucu accauccgaa     1140

guaaaccuau gcaacgucga cauauuuaau ccaaaauaug acugcaaaau aaugacuuca     1200

aaaacagacg uauccucauc aguaauaaca uccuuaggag caauaguauc auguuacggc     1260

aagacaaaau guacagccuc aaacaaaaac aaagguauca uuaaaaccuu cuccaacggc     1320

ugcgacuacg uaucaaauaa aggugucgau acaguaucag uaggaaacac acucuauuac     1380

guuaauaaac aagaaggaaa gucauuauac guaaaaggag aaccaauaau caauuucuac     1440

gauccccuag ucuuucccuc agaugaauuu gacgcaagca ucucucaagu caacgaaaaa     1500

auaaaccaau cccuagccuu cauaagaaaa ucagaugaac uacuucauaa cgucaacgcc     1560

ggaaaaucaa caaccaacau aaugaucacu acaaucauaa uuguaauuau aguaauacua     1620

cuaucgcuaa uugccguugg acuacuacua uauuguaaag caagaucaac acccguuacu     1680

cuauccaaag aucaauuauc aggaaucaac aacauagccu ucucaaauua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6842
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6842
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu uaaagccaac gcaauaacca caauccucac cgccgucaca      180

uucugcuucg ccucgggaca aaacauaacc gaagaauuuu accagucuac cugcuccgcc      240

gucuccaagg guuaccucuc cgcgcuccgc accggguggu acaccagcgu uaucaccauc      300

gaacuaucua acauaaaaga aaacaagugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caagaaugcc gucaccgaac uacaaaugcu caugugcucc      420

acccccgcca ccggauccgg cuccgccauu gccuccggcg ucgccguaug caaaguccuu      480

cacuuggaag gagaaguuaa caaaauaaaa agcgcccucc ugucgaccaa caaagcggug      540

gucagccucu ccaacggcgu cucuguccuc accuucaaag uccucgaccu caagaacuac      600

auagauaaac aacuacuccc cauccuaaac aaacagucau gcagcauauc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaac cgccuccuug aaaucacccg cgaguucucu      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucacaaacuc cgaacuccuc      780

agccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gucaacaauc auacucaauc augugcauca uuaaagaaga aguccucgca      900

uacgucgucc aacucccccu cuaugggguc aucgacaccc caugcuggaa acuccacacc      960

ucuccccuau gcaccaccaa caccaaagaa ggcuccaaca ucugccuaac ccgaaccgac     1020

cgcggauggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgaaacaugu     1080

aaagucugcu ccaaccgugu guucugcgac accaugaacu cacuaacccu ccccuccgaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau aaugaccagc     1200

aaaacagacg uauccucuag cgucauuacc agccuaggug caaucguguc cugcuacggc     1260

aaaacaaaau gcaccgccuc caacaaaaau aaaggaauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg ucagcaacaa aggagucgac accgucuccg uaggaaauac ucuauacuau     1380

gucaacaaac aagaggguaa aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc ugacgaguuc gacgccagca uaucacaagu aaacgaaaag     1500

aucaaccaau cccucgcauu cauucgcaaa uccgacgaac uccuacacaa cgucaacgcc     1560

ggaaaaucca ccaccaacau caugaucacu acuaucauua ucgucaucau cgucauccuc     1620

cucucccuca ucgcagucgg ccuucuacuc uacugcaagg cacgcucuac acccguaacc     1680

cugucuaaag accaacucuc cggcaucaac aacaucgcuu ucuccaacua aggacuaguc     1740

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  6843
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6843
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6844
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6844
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cuccaccccg     1620

gugacccuga gcaaggacca gcuguccggg aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6845
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6845
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6846
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6846
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gucuacaccg     1620

gugaccuuga gcaaagacca gcuguccggc aucaacaaua uagcuuucuc aaacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6847
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6847
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6848
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6848
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cuccacaccu     1620

gugacccuga gcaaagacca gcuuucuggg aucaacaaua uugcguucuc caacugagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6849
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6849
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacucaaa gcaaaugcaa uuaccacuau acucacagcu      120

guaacuuuuu guuucgccuc aggacaaaac aucacagaag aauuuuauca auccacaugc      180

ucugccguau caaaaggcua ccuaucugcc cuaagaacag guugguacac aucuguaaua      240

acaaucgaau uauccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaaac aagaauuaga uaaauauaaa aacgcaguaa cagaacuaca aaugcuaaug      360

ugcucuacac ccgccacagg aucaggaucc gcaaucgcuu cuggaguagc cguuugcaaa      420

guauuacacc uagaaggaga aguaaauaaa auaaaauccg cacuacuauc aacuaauaaa      480

gcaguaguau cacuuucuaa ugguguauca guauuaacau ucaaaguccu cgaccuaaaa      540

aauuacaucg acaaacaacu auuacccauc cuuaauaaac aaucaugcuc cauaucaaac      600

auagaaacug ucauggaauu ucaacaaaaa aacaauagac uucuagaaau cacaagagaa      660

uuuucuguaa augcaggagu aacuacacca guaucaacau auauguuaac caacuccgaa      720

cuacuaucac ucauaaacga caugccaaua acaaacgacc aaaaaaaacu aaugucaaau      780

aacguucaaa uaguaagaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu uccccuauac ggaguaauag acaccccuug cuggaaacuc      900

cacaccucac cacuaugcac uacaaacaca aaagaagguu ccaacaucug cuuaacaaga      960

accgaucgag gaugguacug cgacaacgcu gguuccguau cuuucuuccc acaagcagaa     1020

acaugcaaag uaugcuccaa uagaguauuc ugcgacacca ugaacucacu aacucuacca     1080

uccgaaguaa accuaugcaa cgucgacaua uuuaauccaa aauaugacug caaaauaaug     1140

acuucaaaaa cagacguauc cucaucagua auaacauccu uaggagcaau aguaucaugu     1200

uacggcaaga caaaauguac agccucaaac aaaaacaaag guaucauuaa aaccuucucc     1260

aacggcugcg acuacguauc aaauaaaggu gucgauacag uaucaguagg aaacacacuc     1320

uauuacguua auaaacaaga aggaaaguca uuauacguaa aaggagaacc aauaaucaau     1380

uucuacgauc cccuagucuu ucccucagau gaauuugacg caagcaucuc ucaagucaac     1440

gaaaaaauaa accaaucccu agccuucaua agaaaaucag augaacuacu ucauaacguc     1500

aacgccggaa aaucaacaac caacauaaug aucacuacaa ucauaauugu aauuauagua     1560

auacuacuau cgcuaauugc cguuggacua cuacuauauu guaaagcaag aucaacaccc     1620

guuacucuau ccaaagauca auuaucagga aucaacaaca uagccuucuc aaauuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6850
<211>  1876
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6850
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuuaaa gccaacgcaa uaaccacaau ccucaccgcc      120

gucacauucu gcuucgccuc gggacaaaac auaaccgaag aauuuuacca gucuaccugc      180

uccgccgucu ccaaggguua ccucuccgcg cuccgcaccg ggugguacac cagcguuauc      240

accaucgaac uaucuaacau aaaagaaaac aagugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaag aaugccguca ccgaacuaca aaugcucaug      360

ugcuccaccc ccgccaccgg auccggcucc gccauugccu ccggcgucgc cguaugcaaa      420

guccuucacu uggaaggaga aguuaacaaa auaaaaagcg cccuccuguc gaccaacaaa      480

gcggugguca gccucuccaa cggcgucucu guccucaccu ucaaaguccu cgaccucaag      540

aacuacauag auaaacaacu acuccccauc cuaaacaaac agucaugcag cauauccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaccgcc uccuugaaau cacccgcgag      660

uucucuguca acgccggcgu caccaccccc gucuccaccu acaugcucac aaacuccgaa      720

cuccucagcc ucaucaacga caugccaauc accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucguca acaaucauac ucaaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg ucguccaacu cccccucuau ggggucaucg acaccccaug cuggaaacuc      900

cacaccucuc cccuaugcac caccaacacc aaagaaggcu ccaacaucug ccuaacccga      960

accgaccgcg gaugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgaa     1020

acauguaaag ucugcuccaa ccguguguuc ugcgacacca ugaacucacu aacccucccc     1080

uccgaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaauaaug     1140

accagcaaaa cagacguauc cucuagcguc auuaccagcc uaggugcaau cguguccugc     1200

uacggcaaaa caaaaugcac cgccuccaac aaaaauaaag gaaucauaaa aaccuucucc     1260

aacggcugcg acuacgucag caacaaagga gucgacaccg ucuccguagg aaauacucua     1320

uacuauguca acaaacaaga ggguaaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccucugac gaguucgacg ccagcauauc acaaguaaac     1440

gaaaagauca accaaucccu cgcauucauu cgcaaauccg acgaacuccu acacaacguc     1500

aacgccggaa aauccaccac caacaucaug aucacuacua ucauuaucgu caucaucguc     1560

auccuccucu cccucaucgc agucggccuu cuacucuacu gcaaggcacg cucuacaccc     1620

guaacccugu cuaaagacca acucuccggc aucaacaaca ucgcuuucuc caacuaagga     1680

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1740

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1860

cagagccacc agaauu                                                     1876


<210>  6851
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6851
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1800

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6852
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6852
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      540

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      600

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      660

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      720

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      840

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg     1140

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1200

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1260

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1380

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1440

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1500

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1740

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu ccaccccggu gacccugagc     1800

aaggaccagc uguccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6853
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6853
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      780

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1500

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1800

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6854
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6854
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      540

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      600

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      660

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      720

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      780

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      840

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      900

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      960

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua     1020

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca     1080

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc     1140

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1200

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1260

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1320

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1380

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1440

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1500

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1560

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1620

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1680

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1740

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu cuacaccggu gaccuugagc     1800

aaagaccagc uguccggcau caacaauaua gcuuucucaa acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6855
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6855
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      780

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1800

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6856
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6856
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      540

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      600

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      660

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      720

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      780

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      840

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      900

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      960

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug     1020

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu     1080

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga     1140

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1200

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1260

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1320

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1380

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1440

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1500

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1560

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1620

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1680

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1740

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu ccacaccugu gacccugagc     1800

aaagaccagc uuucugggau caacaauauu gcguucucca acugaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6857
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6857
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaauuacuca uacucaaagc aaaugcaauu accacuauac ucacagcugu aacuuuuugu      300

uucgccucag gacaaaacau cacagaagaa uuuuaucaau ccacaugcuc ugccguauca      360

aaaggcuacc uaucugcccu aagaacaggu ugguacacau cuguaauaac aaucgaauua      420

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaaacaa      480

gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa ugcuaaugug cucuacaccc      540

gccacaggau caggauccgc aaucgcuucu ggaguagccg uuugcaaagu auuacaccua      600

gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa cuaauaaagc aguaguauca      660

cuuucuaaug guguaucagu auuaacauuc aaaguccucg accuaaaaaa uuacaucgac      720

aaacaacuau uacccauccu uaauaaacaa ucaugcucca uaucaaacau agaaacuguc      780

auggaauuuc aacaaaaaaa caauagacuu cuagaaauca caagagaauu uucuguaaau      840

gcaggaguaa cuacaccagu aucaacauau auguuaacca acuccgaacu acuaucacuc      900

auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguucaaaua      960

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguuuu agcauacguc     1020

guacaacuuc cccuauacgg aguaauagac accccuugcu ggaaacucca caccucacca     1080

cuaugcacua caaacacaaa agaagguucc aacaucugcu uaacaagaac cgaucgagga     1140

ugguacugcg acaacgcugg uuccguaucu uucuucccac aagcagaaac augcaaagua     1200

ugcuccaaua gaguauucug cgacaccaug aacucacuaa cucuaccauc cgaaguaaac     1260

cuaugcaacg ucgacauauu uaauccaaaa uaugacugca aaauaaugac uucaaaaaca     1320

gacguauccu caucaguaau aacauccuua ggagcaauag uaucauguua cggcaagaca     1380

aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa ccuucuccaa cggcugcgac     1440

uacguaucaa auaaaggugu cgauacagua ucaguaggaa acacacucua uuacguuaau     1500

aaacaagaag gaaagucauu auacguaaaa ggagaaccaa uaaucaauuu cuacgauccc     1560

cuagucuuuc ccucagauga auuugacgca agcaucucuc aagucaacga aaaaauaaac     1620

caaucccuag ccuucauaag aaaaucagau gaacuacuuc auaacgucaa cgccggaaaa     1680

ucaacaacca acauaaugau cacuacaauc auaauuguaa uuauaguaau acuacuaucg     1740

cuaauugccg uuggacuacu acuauauugu aaagcaagau caacacccgu uacucuaucc     1800

aaagaucaau uaucaggaau caacaacaua gccuucucaa auuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6858
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6858
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuca uacuuaaagc caacgcaaua accacaaucc ucaccgccgu cacauucugc      300

uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu cuaccugcuc cgccgucucc      360

aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca gcguuaucac caucgaacua      420

ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa aagucaaacu caucaaacaa      480

gaacuagaca aauacaagaa ugccgucacc gaacuacaaa ugcucaugug cuccaccccc      540

gccaccggau ccggcuccgc cauugccucc ggcgucgccg uaugcaaagu ccuucacuug      600

gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga ccaacaaagc gguggucagc      660

cucuccaacg gcgucucugu ccucaccuuc aaaguccucg accucaagaa cuacauagau      720

aaacaacuac uccccauccu aaacaaacag ucaugcagca uauccaacau cgaaaccguc      780

auggaguucc aacagaaaaa caaccgccuc cuugaaauca cccgcgaguu cucugucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacaa acuccgaacu ccucagccuc      900

aucaacgaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      960

guucgucaac aaucauacuc aaucaugugc aucauuaaag aagaaguccu cgcauacguc     1020

guccaacucc cccucuaugg ggucaucgac accccaugcu ggaaacucca caccucuccc     1080

cuaugcacca ccaacaccaa agaaggcucc aacaucugcc uaacccgaac cgaccgcgga     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgaaac auguaaaguc     1200

ugcuccaacc guguguucug cgacaccaug aacucacuaa cccuccccuc cgaagucaac     1260

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaauaaugac cagcaaaaca     1320

gacguauccu cuagcgucau uaccagccua ggugcaaucg uguccugcua cggcaaaaca     1380

aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa ccuucuccaa cggcugcgac     1440

uacgucagca acaaaggagu cgacaccguc uccguaggaa auacucuaua cuaugucaac     1500

aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccucugacga guucgacgcc agcauaucac aaguaaacga aaagaucaac     1620

caaucccucg cauucauucg caaauccgac gaacuccuac acaacgucaa cgccggaaaa     1680

uccaccacca acaucaugau cacuacuauc auuaucguca ucaucgucau ccuccucucc     1740

cucaucgcag ucggccuucu acucuacugc aaggcacgcu cuacacccgu aacccugucu     1800

aaagaccaac ucuccggcau caacaacauc gcuuucucca acuaaggacu aguguccacc     1860

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1920

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6859
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6859
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6860
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6860
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      480

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1320

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu ccaccccggu gacccugagc     1620

aaggaccagc uguccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6861
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6861
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6862
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6862
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      420

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      480

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      540

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      720

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      780

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua      840

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca      900

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc      960

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1020

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1080

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1140

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1200

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1260

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1320

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1380

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1440

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1500

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1560

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu cuacaccggu gaccuugagc     1620

aaagaccagc uguccggcau caacaauaua gcuuucucaa acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6863
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6863
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6864
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6864
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      420

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      480

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      540

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      720

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      780

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug      840

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu      900

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga      960

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1020

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1080

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1140

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1260

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1380

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1440

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1500

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1560

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu ccacaccugu gacccugagc     1620

aaagaccagc uuucugggau caacaauauu gcguucucca acugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6865
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6865
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaauuacuca uacucaaagc aaaugcaauu accacuauac ucacagcugu aacuuuuugu      120

uucgccucag gacaaaacau cacagaagaa uuuuaucaau ccacaugcuc ugccguauca      180

aaaggcuacc uaucugcccu aagaacaggu ugguacacau cuguaauaac aaucgaauua      240

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaaacaa      300

gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa ugcuaaugug cucuacaccc      360

gccacaggau caggauccgc aaucgcuucu ggaguagccg uuugcaaagu auuacaccua      420

gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa cuaauaaagc aguaguauca      480

cuuucuaaug guguaucagu auuaacauuc aaaguccucg accuaaaaaa uuacaucgac      540

aaacaacuau uacccauccu uaauaaacaa ucaugcucca uaucaaacau agaaacuguc      600

auggaauuuc aacaaaaaaa caauagacuu cuagaaauca caagagaauu uucuguaaau      660

gcaggaguaa cuacaccagu aucaacauau auguuaacca acuccgaacu acuaucacuc      720

auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguucaaaua      780

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguuuu agcauacguc      840

guacaacuuc cccuauacgg aguaauagac accccuugcu ggaaacucca caccucacca      900

cuaugcacua caaacacaaa agaagguucc aacaucugcu uaacaagaac cgaucgagga      960

ugguacugcg acaacgcugg uuccguaucu uucuucccac aagcagaaac augcaaagua     1020

ugcuccaaua gaguauucug cgacaccaug aacucacuaa cucuaccauc cgaaguaaac     1080

cuaugcaacg ucgacauauu uaauccaaaa uaugacugca aaauaaugac uucaaaaaca     1140

gacguauccu caucaguaau aacauccuua ggagcaauag uaucauguua cggcaagaca     1200

aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa ccuucuccaa cggcugcgac     1260

uacguaucaa auaaaggugu cgauacagua ucaguaggaa acacacucua uuacguuaau     1320

aaacaagaag gaaagucauu auacguaaaa ggagaaccaa uaaucaauuu cuacgauccc     1380

cuagucuuuc ccucagauga auuugacgca agcaucucuc aagucaacga aaaaauaaac     1440

caaucccuag ccuucauaag aaaaucagau gaacuacuuc auaacgucaa cgccggaaaa     1500

ucaacaacca acauaaugau cacuacaauc auaauuguaa uuauaguaau acuacuaucg     1560

cuaauugccg uuggacuacu acuauauugu aaagcaagau caacacccgu uacucuaucc     1620

aaagaucaau uaucaggaau caacaacaua gccuucucaa auuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6866
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6866
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuca uacuuaaagc caacgcaaua accacaaucc ucaccgccgu cacauucugc      120

uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu cuaccugcuc cgccgucucc      180

aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca gcguuaucac caucgaacua      240

ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa aagucaaacu caucaaacaa      300

gaacuagaca aauacaagaa ugccgucacc gaacuacaaa ugcucaugug cuccaccccc      360

gccaccggau ccggcuccgc cauugccucc ggcgucgccg uaugcaaagu ccuucacuug      420

gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga ccaacaaagc gguggucagc      480

cucuccaacg gcgucucugu ccucaccuuc aaaguccucg accucaagaa cuacauagau      540

aaacaacuac uccccauccu aaacaaacag ucaugcagca uauccaacau cgaaaccguc      600

auggaguucc aacagaaaaa caaccgccuc cuugaaauca cccgcgaguu cucugucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacaa acuccgaacu ccucagccuc      720

aucaacgaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      780

guucgucaac aaucauacuc aaucaugugc aucauuaaag aagaaguccu cgcauacguc      840

guccaacucc cccucuaugg ggucaucgac accccaugcu ggaaacucca caccucuccc      900

cuaugcacca ccaacaccaa agaaggcucc aacaucugcc uaacccgaac cgaccgcgga      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgaaac auguaaaguc     1020

ugcuccaacc guguguucug cgacaccaug aacucacuaa cccuccccuc cgaagucaac     1080

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaauaaugac cagcaaaaca     1140

gacguauccu cuagcgucau uaccagccua ggugcaaucg uguccugcua cggcaaaaca     1200

aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa ccuucuccaa cggcugcgac     1260

uacgucagca acaaaggagu cgacaccguc uccguaggaa auacucuaua cuaugucaac     1320

aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccucugacga guucgacgcc agcauaucac aaguaaacga aaagaucaac     1440

caaucccucg cauucauucg caaauccgac gaacuccuac acaacgucaa cgccggaaaa     1500

uccaccacca acaucaugau cacuacuauc auuaucguca ucaucgucau ccuccucucc     1560

cucaucgcag ucggccuucu acucuacugc aaggcacgcu cuacacccgu aacccugucu     1620

aaagaccaac ucuccggcau caacaacauc gcuuucucca acuaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  6867
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6867
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6868
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6868
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

ccaccccggu gacccugagc aaggaccagc uguccgggau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6869
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6869
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6870
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6870
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

cuacaccggu gaccuugagc aaagaccagc uguccggcau caacaauaua gcuuucucaa     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6871
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6871
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6872
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6872
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

ccacaccugu gacccugagc aaagaccagc uuucugggau caacaauauu gcguucucca     1680

acugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6873
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6873
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacucaaagc aaaugcaauu accacuauac      120

ucacagcugu aacuuuuugu uucgccucag gacaaaacau cacagaagaa uuuuaucaau      180

ccacaugcuc ugccguauca aaaggcuacc uaucugcccu aagaacaggu ugguacacau      240

cuguaauaac aaucgaauua uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaaacaa gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa      360

ugcuaaugug cucuacaccc gccacaggau caggauccgc aaucgcuucu ggaguagccg      420

uuugcaaagu auuacaccua gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa      480

cuaauaaagc aguaguauca cuuucuaaug guguaucagu auuaacauuc aaaguccucg      540

accuaaaaaa uuacaucgac aaacaacuau uacccauccu uaauaaacaa ucaugcucca      600

uaucaaacau agaaacuguc auggaauuuc aacaaaaaaa caauagacuu cuagaaauca      660

caagagaauu uucuguaaau gcaggaguaa cuacaccagu aucaacauau auguuaacca      720

acuccgaacu acuaucacuc auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa      780

ugucaaauaa cguucaaaua guaagacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguuuu agcauacguc guacaacuuc cccuauacgg aguaauagac accccuugcu      900

ggaaacucca caccucacca cuaugcacua caaacacaaa agaagguucc aacaucugcu      960

uaacaagaac cgaucgagga ugguacugcg acaacgcugg uuccguaucu uucuucccac     1020

aagcagaaac augcaaagua ugcuccaaua gaguauucug cgacaccaug aacucacuaa     1080

cucuaccauc cgaaguaaac cuaugcaacg ucgacauauu uaauccaaaa uaugacugca     1140

aaauaaugac uucaaaaaca gacguauccu caucaguaau aacauccuua ggagcaauag     1200

uaucauguua cggcaagaca aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa     1260

ccuucuccaa cggcugcgac uacguaucaa auaaaggugu cgauacagua ucaguaggaa     1320

acacacucua uuacguuaau aaacaagaag gaaagucauu auacguaaaa ggagaaccaa     1380

uaaucaauuu cuacgauccc cuagucuuuc ccucagauga auuugacgca agcaucucuc     1440

aagucaacga aaaaauaaac caaucccuag ccuucauaag aaaaucagau gaacuacuuc     1500

auaacgucaa cgccggaaaa ucaacaacca acauaaugau cacuacaauc auaauuguaa     1560

uuauaguaau acuacuaucg cuaauugccg uuggacuacu acuauauugu aaagcaagau     1620

caacacccgu uacucuaucc aaagaucaau uaucaggaau caacaacaua gccuucucaa     1680

auuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6874
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6874
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuuaaagc caacgcaaua accacaaucc      120

ucaccgccgu cacauucugc uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu      180

cuaccugcuc cgccgucucc aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca      240

gcguuaucac caucgaacua ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaagaa ugccgucacc gaacuacaaa      360

ugcucaugug cuccaccccc gccaccggau ccggcuccgc cauugccucc ggcgucgccg      420

uaugcaaagu ccuucacuug gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga      480

ccaacaaagc gguggucagc cucuccaacg gcgucucugu ccucaccuuc aaaguccucg      540

accucaagaa cuacauagau aaacaacuac uccccauccu aaacaaacag ucaugcagca      600

uauccaacau cgaaaccguc auggaguucc aacagaaaaa caaccgccuc cuugaaauca      660

cccgcgaguu cucugucaac gccggcguca ccacccccgu cuccaccuac augcucacaa      720

acuccgaacu ccucagccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgucaac aaucauacuc aaucaugugc aucauuaaag      840

aagaaguccu cgcauacguc guccaacucc cccucuaugg ggucaucgac accccaugcu      900

ggaaacucca caccucuccc cuaugcacca ccaacaccaa agaaggcucc aacaucugcc      960

uaacccgaac cgaccgcgga ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgaaac auguaaaguc ugcuccaacc guguguucug cgacaccaug aacucacuaa     1080

cccuccccuc cgaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaauaaugac cagcaaaaca gacguauccu cuagcgucau uaccagccua ggugcaaucg     1200

uguccugcua cggcaaaaca aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa     1260

ccuucuccaa cggcugcgac uacgucagca acaaaggagu cgacaccguc uccguaggaa     1320

auacucuaua cuaugucaac aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccucugacga guucgacgcc agcauaucac     1440

aaguaaacga aaagaucaac caaucccucg cauucauucg caaauccgac gaacuccuac     1500

acaacgucaa cgccggaaaa uccaccacca acaucaugau cacuacuauc auuaucguca     1560

ucaucgucau ccuccucucc cucaucgcag ucggccuucu acucuacugc aaggcacgcu     1620

cuacacccgu aacccugucu aaagaccaac ucuccggcau caacaacauc gcuuucucca     1680

acuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1740

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6875
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6875
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6876
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6876
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

ccaccccggu gacccugagc aaggaccagc uguccgggau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6877
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6877
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6878
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6878
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

cuacaccggu gaccuugagc aaagaccagc uguccggcau caacaauaua gcuuucucaa     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6879
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6879
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6880
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6880
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

ccacaccugu gacccugagc aaagaccagc uuucugggau caacaauauu gcguucucca     1680

acugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6881
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6881
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacucaaagc aaaugcaauu accacuauac      120

ucacagcugu aacuuuuugu uucgccucag gacaaaacau cacagaagaa uuuuaucaau      180

ccacaugcuc ugccguauca aaaggcuacc uaucugcccu aagaacaggu ugguacacau      240

cuguaauaac aaucgaauua uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaaacaa gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa      360

ugcuaaugug cucuacaccc gccacaggau caggauccgc aaucgcuucu ggaguagccg      420

uuugcaaagu auuacaccua gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa      480

cuaauaaagc aguaguauca cuuucuaaug guguaucagu auuaacauuc aaaguccucg      540

accuaaaaaa uuacaucgac aaacaacuau uacccauccu uaauaaacaa ucaugcucca      600

uaucaaacau agaaacuguc auggaauuuc aacaaaaaaa caauagacuu cuagaaauca      660

caagagaauu uucuguaaau gcaggaguaa cuacaccagu aucaacauau auguuaacca      720

acuccgaacu acuaucacuc auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa      780

ugucaaauaa cguucaaaua guaagacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguuuu agcauacguc guacaacuuc cccuauacgg aguaauagac accccuugcu      900

ggaaacucca caccucacca cuaugcacua caaacacaaa agaagguucc aacaucugcu      960

uaacaagaac cgaucgagga ugguacugcg acaacgcugg uuccguaucu uucuucccac     1020

aagcagaaac augcaaagua ugcuccaaua gaguauucug cgacaccaug aacucacuaa     1080

cucuaccauc cgaaguaaac cuaugcaacg ucgacauauu uaauccaaaa uaugacugca     1140

aaauaaugac uucaaaaaca gacguauccu caucaguaau aacauccuua ggagcaauag     1200

uaucauguua cggcaagaca aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa     1260

ccuucuccaa cggcugcgac uacguaucaa auaaaggugu cgauacagua ucaguaggaa     1320

acacacucua uuacguuaau aaacaagaag gaaagucauu auacguaaaa ggagaaccaa     1380

uaaucaauuu cuacgauccc cuagucuuuc ccucagauga auuugacgca agcaucucuc     1440

aagucaacga aaaaauaaac caaucccuag ccuucauaag aaaaucagau gaacuacuuc     1500

auaacgucaa cgccggaaaa ucaacaacca acauaaugau cacuacaauc auaauuguaa     1560

uuauaguaau acuacuaucg cuaauugccg uuggacuacu acuauauugu aaagcaagau     1620

caacacccgu uacucuaucc aaagaucaau uaucaggaau caacaacaua gccuucucaa     1680

auuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6882
<211>  1948
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6882
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuuaaagc caacgcaaua accacaaucc      120

ucaccgccgu cacauucugc uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu      180

cuaccugcuc cgccgucucc aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca      240

gcguuaucac caucgaacua ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaagaa ugccgucacc gaacuacaaa      360

ugcucaugug cuccaccccc gccaccggau ccggcuccgc cauugccucc ggcgucgccg      420

uaugcaaagu ccuucacuug gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga      480

ccaacaaagc gguggucagc cucuccaacg gcgucucugu ccucaccuuc aaaguccucg      540

accucaagaa cuacauagau aaacaacuac uccccauccu aaacaaacag ucaugcagca      600

uauccaacau cgaaaccguc auggaguucc aacagaaaaa caaccgccuc cuugaaauca      660

cccgcgaguu cucugucaac gccggcguca ccacccccgu cuccaccuac augcucacaa      720

acuccgaacu ccucagccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgucaac aaucauacuc aaucaugugc aucauuaaag      840

aagaaguccu cgcauacguc guccaacucc cccucuaugg ggucaucgac accccaugcu      900

ggaaacucca caccucuccc cuaugcacca ccaacaccaa agaaggcucc aacaucugcc      960

uaacccgaac cgaccgcgga ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgaaac auguaaaguc ugcuccaacc guguguucug cgacaccaug aacucacuaa     1080

cccuccccuc cgaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaauaaugac cagcaaaaca gacguauccu cuagcgucau uaccagccua ggugcaaucg     1200

uguccugcua cggcaaaaca aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa     1260

ccuucuccaa cggcugcgac uacgucagca acaaaggagu cgacaccguc uccguaggaa     1320

auacucuaua cuaugucaac aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccucugacga guucgacgcc agcauaucac     1440

aaguaaacga aaagaucaac caaucccucg cauucauucg caaauccgac gaacuccuac     1500

acaacgucaa cgccggaaaa uccaccacca acaucaugau cacuacuauc auuaucguca     1560

ucaucgucau ccuccucucc cucaucgcag ucggccuucu acucuacugc aaggcacgcu     1620

cuacacccgu aacccugucu aaagaccaac ucuccggcau caacaacauc gcuuucucca     1680

acuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1740

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1800

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1920

aaaggcucuu uucagagcca ccagaauu                                        1948


<210>  6883
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6883
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6884
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6884
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcuccac cccggugacc     1680

cugagcaagg accagcuguc cgggaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6885
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6885
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6886
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6886
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggucuac accggugacc     1680

uugagcaaag accagcuguc cggcaucaac aauauagcuu ucucaaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6887
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6887
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6888
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6888
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcuccac accugugacc     1680

cugagcaaag accagcuuuc ugggaucaac aauauugcgu ucuccaacug aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6889
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6889
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu caaagcaaau gcaauuacca cuauacucac agcuguaacu      180

uuuuguuucg ccucaggaca aaacaucaca gaagaauuuu aucaauccac augcucugcc      240

guaucaaaag gcuaccuauc ugcccuaaga acagguuggu acacaucugu aauaacaauc      300

gaauuaucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aaacaagaau uagauaaaua uaaaaacgca guaacagaac uacaaaugcu aaugugcucu      420

acacccgcca caggaucagg auccgcaauc gcuucuggag uagccguuug caaaguauua      480

caccuagaag gagaaguaaa uaaaauaaaa uccgcacuac uaucaacuaa uaaagcagua      540

guaucacuuu cuaauggugu aucaguauua acauucaaag uccucgaccu aaaaaauuac      600

aucgacaaac aacuauuacc cauccuuaau aaacaaucau gcuccauauc aaacauagaa      660

acugucaugg aauuucaaca aaaaaacaau agacuucuag aaaucacaag agaauuuucu      720

guaaaugcag gaguaacuac accaguauca acauauaugu uaaccaacuc cgaacuacua      780

ucacucauaa acgacaugcc aauaacaaac gaccaaaaaa aacuaauguc aaauaacguu      840

caaauaguaa gacaacaauc auacucaauc augugcauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuuccccu auacggagua auagacaccc cuugcuggaa acuccacacc      960

ucaccacuau gcacuacaaa cacaaaagaa gguuccaaca ucugcuuaac aagaaccgau     1020

cgaggauggu acugcgacaa cgcugguucc guaucuuucu ucccacaagc agaaacaugc     1080

aaaguaugcu ccaauagagu auucugcgac accaugaacu cacuaacucu accauccgaa     1140

guaaaccuau gcaacgucga cauauuuaau ccaaaauaug acugcaaaau aaugacuuca     1200

aaaacagacg uauccucauc aguaauaaca uccuuaggag caauaguauc auguuacggc     1260

aagacaaaau guacagccuc aaacaaaaac aaagguauca uuaaaaccuu cuccaacggc     1320

ugcgacuacg uaucaaauaa aggugucgau acaguaucag uaggaaacac acucuauuac     1380

guuaauaaac aagaaggaaa gucauuauac guaaaaggag aaccaauaau caauuucuac     1440

gauccccuag ucuuucccuc agaugaauuu gacgcaagca ucucucaagu caacgaaaaa     1500

auaaaccaau cccuagccuu cauaagaaaa ucagaugaac uacuucauaa cgucaacgcc     1560

ggaaaaucaa caaccaacau aaugaucacu acaaucauaa uuguaauuau aguaauacua     1620

cuaucgcuaa uugccguugg acuacuacua uauuguaaag caagaucaac acccguuacu     1680

cuauccaaag aucaauuauc aggaaucaac aacauagccu ucucaaauua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6890
<211>  2010
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6890
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu uaaagccaac gcaauaacca caauccucac cgccgucaca      180

uucugcuucg ccucgggaca aaacauaacc gaagaauuuu accagucuac cugcuccgcc      240

gucuccaagg guuaccucuc cgcgcuccgc accggguggu acaccagcgu uaucaccauc      300

gaacuaucua acauaaaaga aaacaagugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caagaaugcc gucaccgaac uacaaaugcu caugugcucc      420

acccccgcca ccggauccgg cuccgccauu gccuccggcg ucgccguaug caaaguccuu      480

cacuuggaag gagaaguuaa caaaauaaaa agcgcccucc ugucgaccaa caaagcggug      540

gucagccucu ccaacggcgu cucuguccuc accuucaaag uccucgaccu caagaacuac      600

auagauaaac aacuacuccc cauccuaaac aaacagucau gcagcauauc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaac cgccuccuug aaaucacccg cgaguucucu      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucacaaacuc cgaacuccuc      780

agccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gucaacaauc auacucaauc augugcauca uuaaagaaga aguccucgca      900

uacgucgucc aacucccccu cuaugggguc aucgacaccc caugcuggaa acuccacacc      960

ucuccccuau gcaccaccaa caccaaagaa ggcuccaaca ucugccuaac ccgaaccgac     1020

cgcggauggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgaaacaugu     1080

aaagucugcu ccaaccgugu guucugcgac accaugaacu cacuaacccu ccccuccgaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau aaugaccagc     1200

aaaacagacg uauccucuag cgucauuacc agccuaggug caaucguguc cugcuacggc     1260

aaaacaaaau gcaccgccuc caacaaaaau aaaggaauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg ucagcaacaa aggagucgac accgucuccg uaggaaauac ucuauacuau     1380

gucaacaaac aagaggguaa aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc ugacgaguuc gacgccagca uaucacaagu aaacgaaaag     1500

aucaaccaau cccucgcauu cauucgcaaa uccgacgaac uccuacacaa cgucaacgcc     1560

ggaaaaucca ccaccaacau caugaucacu acuaucauua ucgucaucau cgucauccuc     1620

cucucccuca ucgcagucgg ccuucuacuc uacugcaagg cacgcucuac acccguaacc     1680

cugucuaaag accaacucuc cggcaucaac aacaucgcuu ucuccaacua aggacuagua     1740

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1800

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1860

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1980

ccaaaggcuc uuuucagagc caccagaauu                                      2010


<210>  6891
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6891
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6892
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6892
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcuc caccccggug acccugagca aggaccagcu guccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6893
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6893
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6894
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6894
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacgguc uacaccggug accuugagca aagaccagcu guccggcauc     1680

aacaauauag cuuucucaaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6895
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6895
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6896
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6896
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcuc cacaccugug acccugagca aagaccagcu uucugggauc     1680

aacaauauug cguucuccaa cugaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6897
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6897
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acucaaagca      120

aaugcaauua ccacuauacu cacagcugua acuuuuuguu ucgccucagg acaaaacauc      180

acagaagaau uuuaucaauc cacaugcucu gccguaucaa aaggcuaccu aucugcccua      240

agaacagguu gguacacauc uguaauaaca aucgaauuau ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaaacaag aauuagauaa auauaaaaac      360

gcaguaacag aacuacaaau gcuaaugugc ucuacacccg ccacaggauc aggauccgca      420

aucgcuucug gaguagccgu uugcaaagua uuacaccuag aaggagaagu aaauaaaaua      480

aaauccgcac uacuaucaac uaauaaagca guaguaucac uuucuaaugg uguaucagua      540

uuaacauuca aaguccucga ccuaaaaaau uacaucgaca aacaacuauu acccauccuu      600

aauaaacaau caugcuccau aucaaacaua gaaacuguca uggaauuuca acaaaaaaac      660

aauagacuuc uagaaaucac aagagaauuu ucuguaaaug caggaguaac uacaccagua      720

ucaacauaua uguuaaccaa cuccgaacua cuaucacuca uaaacgacau gccaauaaca      780

aacgaccaaa aaaaacuaau gucaaauaac guucaaauag uaagacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguuuua gcauacgucg uacaacuucc ccuauacgga      900

guaauagaca ccccuugcug gaaacuccac accucaccac uaugcacuac aaacacaaaa      960

gaagguucca acaucugcuu aacaagaacc gaucgaggau gguacugcga caacgcuggu     1020

uccguaucuu ucuucccaca agcagaaaca ugcaaaguau gcuccaauag aguauucugc     1080

gacaccauga acucacuaac ucuaccaucc gaaguaaacc uaugcaacgu cgacauauuu     1140

aauccaaaau augacugcaa aauaaugacu ucaaaaacag acguauccuc aucaguaaua     1200

acauccuuag gagcaauagu aucauguuac ggcaagacaa aauguacagc cucaaacaaa     1260

aacaaaggua ucauuaaaac cuucuccaac ggcugcgacu acguaucaaa uaaagguguc     1320

gauacaguau caguaggaaa cacacucuau uacguuaaua aacaagaagg aaagucauua     1380

uacguaaaag gagaaccaau aaucaauuuc uacgaucccc uagucuuucc cucagaugaa     1440

uuugacgcaa gcaucucuca agucaacgaa aaaauaaacc aaucccuagc cuucauaaga     1500

aaaucagaug aacuacuuca uaacgucaac gccggaaaau caacaaccaa cauaaugauc     1560

acuacaauca uaauuguaau uauaguaaua cuacuaucgc uaauugccgu uggacuacua     1620

cuauauugua aagcaagauc aacacccguu acucuaucca aagaucaauu aucaggaauc     1680

aacaacauag ccuucucaaa uuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6898
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6898
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuuaaagcc      120

aacgcaauaa ccacaauccu caccgccguc acauucugcu ucgccucggg acaaaacaua      180

accgaagaau uuuaccaguc uaccugcucc gccgucucca aggguuaccu cuccgcgcuc      240

cgcaccgggu gguacaccag cguuaucacc aucgaacuau cuaacauaaa agaaaacaag      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaagaau      360

gccgucaccg aacuacaaau gcucaugugc uccacccccg ccaccggauc cggcuccgcc      420

auugccuccg gcgucgccgu augcaaaguc cuucacuugg aaggagaagu uaacaaaaua      480

aaaagcgccc uccugucgac caacaaagcg guggucagcc ucuccaacgg cgucucuguc      540

cucaccuuca aaguccucga ccucaagaac uacauagaua aacaacuacu ccccauccua      600

aacaaacagu caugcagcau auccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaccgccucc uugaaaucac ccgcgaguuc ucugucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucacaaa cuccgaacuc cucagccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgucaaca aucauacuca      840

aucaugugca ucauuaaaga agaaguccuc gcauacgucg uccaacuccc ccucuauggg      900

gucaucgaca ccccaugcug gaaacuccac accucucccc uaugcaccac caacaccaaa      960

gaaggcucca acaucugccu aacccgaacc gaccgcggau gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgaaaca uguaaagucu gcuccaaccg uguguucugc     1080

gacaccauga acucacuaac ccuccccucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aauaaugacc agcaaaacag acguauccuc uagcgucauu     1200

accagccuag gugcaaucgu guccugcuac ggcaaaacaa aaugcaccgc cuccaacaaa     1260

aauaaaggaa ucauaaaaac cuucuccaac ggcugcgacu acgucagcaa caaaggaguc     1320

gacaccgucu ccguaggaaa uacucuauac uaugucaaca aacaagaggg uaaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cucugacgag     1440

uucgacgcca gcauaucaca aguaaacgaa aagaucaacc aaucccucgc auucauucgc     1500

aaauccgacg aacuccuaca caacgucaac gccggaaaau ccaccaccaa caucaugauc     1560

acuacuauca uuaucgucau caucgucauc cuccucuccc ucaucgcagu cggccuucua     1620

cucuacugca aggcacgcuc uacacccgua acccugucua aagaccaacu cuccggcauc     1680

aacaacaucg cuuucuccaa cuaaggacua guguccaccu gucccuccug ggcugcugga     1740

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  6899
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6899
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6900
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6900
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcuccac cccggugacc     1680

cugagcaagg accagcuguc cgggaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6901
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6901
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6902
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6902
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggucuac accggugacc     1680

uugagcaaag accagcuguc cggcaucaac aauauagcuu ucucaaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6903
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6903
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6904
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6904
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcuccac accugugacc     1680

cugagcaaag accagcuuuc ugggaucaac aauauugcgu ucuccaacug aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6905
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6905
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu caaagcaaau gcaauuacca cuauacucac agcuguaacu      180

uuuuguuucg ccucaggaca aaacaucaca gaagaauuuu aucaauccac augcucugcc      240

guaucaaaag gcuaccuauc ugcccuaaga acagguuggu acacaucugu aauaacaauc      300

gaauuaucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aaacaagaau uagauaaaua uaaaaacgca guaacagaac uacaaaugcu aaugugcucu      420

acacccgcca caggaucagg auccgcaauc gcuucuggag uagccguuug caaaguauua      480

caccuagaag gagaaguaaa uaaaauaaaa uccgcacuac uaucaacuaa uaaagcagua      540

guaucacuuu cuaauggugu aucaguauua acauucaaag uccucgaccu aaaaaauuac      600

aucgacaaac aacuauuacc cauccuuaau aaacaaucau gcuccauauc aaacauagaa      660

acugucaugg aauuucaaca aaaaaacaau agacuucuag aaaucacaag agaauuuucu      720

guaaaugcag gaguaacuac accaguauca acauauaugu uaaccaacuc cgaacuacua      780

ucacucauaa acgacaugcc aauaacaaac gaccaaaaaa aacuaauguc aaauaacguu      840

caaauaguaa gacaacaauc auacucaauc augugcauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuuccccu auacggagua auagacaccc cuugcuggaa acuccacacc      960

ucaccacuau gcacuacaaa cacaaaagaa gguuccaaca ucugcuuaac aagaaccgau     1020

cgaggauggu acugcgacaa cgcugguucc guaucuuucu ucccacaagc agaaacaugc     1080

aaaguaugcu ccaauagagu auucugcgac accaugaacu cacuaacucu accauccgaa     1140

guaaaccuau gcaacgucga cauauuuaau ccaaaauaug acugcaaaau aaugacuuca     1200

aaaacagacg uauccucauc aguaauaaca uccuuaggag caauaguauc auguuacggc     1260

aagacaaaau guacagccuc aaacaaaaac aaagguauca uuaaaaccuu cuccaacggc     1320

ugcgacuacg uaucaaauaa aggugucgau acaguaucag uaggaaacac acucuauuac     1380

guuaauaaac aagaaggaaa gucauuauac guaaaaggag aaccaauaau caauuucuac     1440

gauccccuag ucuuucccuc agaugaauuu gacgcaagca ucucucaagu caacgaaaaa     1500

auaaaccaau cccuagccuu cauaagaaaa ucagaugaac uacuucauaa cgucaacgcc     1560

ggaaaaucaa caaccaacau aaugaucacu acaaucauaa uuguaauuau aguaauacua     1620

cuaucgcuaa uugccguugg acuacuacua uauuguaaag caagaucaac acccguuacu     1680

cuauccaaag aucaauuauc aggaaucaac aacauagccu ucucaaauua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6906
<211>  2006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6906
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu uaaagccaac gcaauaacca caauccucac cgccgucaca      180

uucugcuucg ccucgggaca aaacauaacc gaagaauuuu accagucuac cugcuccgcc      240

gucuccaagg guuaccucuc cgcgcuccgc accggguggu acaccagcgu uaucaccauc      300

gaacuaucua acauaaaaga aaacaagugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caagaaugcc gucaccgaac uacaaaugcu caugugcucc      420

acccccgcca ccggauccgg cuccgccauu gccuccggcg ucgccguaug caaaguccuu      480

cacuuggaag gagaaguuaa caaaauaaaa agcgcccucc ugucgaccaa caaagcggug      540

gucagccucu ccaacggcgu cucuguccuc accuucaaag uccucgaccu caagaacuac      600

auagauaaac aacuacuccc cauccuaaac aaacagucau gcagcauauc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaac cgccuccuug aaaucacccg cgaguucucu      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucacaaacuc cgaacuccuc      780

agccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gucaacaauc auacucaauc augugcauca uuaaagaaga aguccucgca      900

uacgucgucc aacucccccu cuaugggguc aucgacaccc caugcuggaa acuccacacc      960

ucuccccuau gcaccaccaa caccaaagaa ggcuccaaca ucugccuaac ccgaaccgac     1020

cgcggauggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgaaacaugu     1080

aaagucugcu ccaaccgugu guucugcgac accaugaacu cacuaacccu ccccuccgaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau aaugaccagc     1200

aaaacagacg uauccucuag cgucauuacc agccuaggug caaucguguc cugcuacggc     1260

aaaacaaaau gcaccgccuc caacaaaaau aaaggaauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg ucagcaacaa aggagucgac accgucuccg uaggaaauac ucuauacuau     1380

gucaacaaac aagaggguaa aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc ugacgaguuc gacgccagca uaucacaagu aaacgaaaag     1500

aucaaccaau cccucgcauu cauucgcaaa uccgacgaac uccuacacaa cgucaacgcc     1560

ggaaaaucca ccaccaacau caugaucacu acuaucauua ucgucaucau cgucauccuc     1620

cucucccuca ucgcagucgg ccuucuacuc uacugcaagg cacgcucuac acccguaacc     1680

cugucuaaag accaacucuc cggcaucaac aacaucgcuu ucuccaacua aggacuagug     1740

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1800

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1860

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1980

aggcucuuuu cagagccacc agaauu                                          2006


<210>  6907
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6907
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6908
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6908
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcuc caccccggug acccugagca aggaccagcu guccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6909
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6909
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6910
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6910
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacgguc uacaccggug accuugagca aagaccagcu guccggcauc     1680

aacaauauag cuuucucaaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6911
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6911
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6912
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6912
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcuc cacaccugug acccugagca aagaccagcu uucugggauc     1680

aacaauauug cguucuccaa cugaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6913
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6913
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acucaaagca      120

aaugcaauua ccacuauacu cacagcugua acuuuuuguu ucgccucagg acaaaacauc      180

acagaagaau uuuaucaauc cacaugcucu gccguaucaa aaggcuaccu aucugcccua      240

agaacagguu gguacacauc uguaauaaca aucgaauuau ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaaacaag aauuagauaa auauaaaaac      360

gcaguaacag aacuacaaau gcuaaugugc ucuacacccg ccacaggauc aggauccgca      420

aucgcuucug gaguagccgu uugcaaagua uuacaccuag aaggagaagu aaauaaaaua      480

aaauccgcac uacuaucaac uaauaaagca guaguaucac uuucuaaugg uguaucagua      540

uuaacauuca aaguccucga ccuaaaaaau uacaucgaca aacaacuauu acccauccuu      600

aauaaacaau caugcuccau aucaaacaua gaaacuguca uggaauuuca acaaaaaaac      660

aauagacuuc uagaaaucac aagagaauuu ucuguaaaug caggaguaac uacaccagua      720

ucaacauaua uguuaaccaa cuccgaacua cuaucacuca uaaacgacau gccaauaaca      780

aacgaccaaa aaaaacuaau gucaaauaac guucaaauag uaagacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguuuua gcauacgucg uacaacuucc ccuauacgga      900

guaauagaca ccccuugcug gaaacuccac accucaccac uaugcacuac aaacacaaaa      960

gaagguucca acaucugcuu aacaagaacc gaucgaggau gguacugcga caacgcuggu     1020

uccguaucuu ucuucccaca agcagaaaca ugcaaaguau gcuccaauag aguauucugc     1080

gacaccauga acucacuaac ucuaccaucc gaaguaaacc uaugcaacgu cgacauauuu     1140

aauccaaaau augacugcaa aauaaugacu ucaaaaacag acguauccuc aucaguaaua     1200

acauccuuag gagcaauagu aucauguuac ggcaagacaa aauguacagc cucaaacaaa     1260

aacaaaggua ucauuaaaac cuucuccaac ggcugcgacu acguaucaaa uaaagguguc     1320

gauacaguau caguaggaaa cacacucuau uacguuaaua aacaagaagg aaagucauua     1380

uacguaaaag gagaaccaau aaucaauuuc uacgaucccc uagucuuucc cucagaugaa     1440

uuugacgcaa gcaucucuca agucaacgaa aaaauaaacc aaucccuagc cuucauaaga     1500

aaaucagaug aacuacuuca uaacgucaac gccggaaaau caacaaccaa cauaaugauc     1560

acuacaauca uaauuguaau uauaguaaua cuacuaucgc uaauugccgu uggacuacua     1620

cuauauugua aagcaagauc aacacccguu acucuaucca aagaucaauu aucaggaauc     1680

aacaacauag ccuucucaaa uuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6914
<211>  1983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6914
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuuaaagcc      120

aacgcaauaa ccacaauccu caccgccguc acauucugcu ucgccucggg acaaaacaua      180

accgaagaau uuuaccaguc uaccugcucc gccgucucca aggguuaccu cuccgcgcuc      240

cgcaccgggu gguacaccag cguuaucacc aucgaacuau cuaacauaaa agaaaacaag      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaagaau      360

gccgucaccg aacuacaaau gcucaugugc uccacccccg ccaccggauc cggcuccgcc      420

auugccuccg gcgucgccgu augcaaaguc cuucacuugg aaggagaagu uaacaaaaua      480

aaaagcgccc uccugucgac caacaaagcg guggucagcc ucuccaacgg cgucucuguc      540

cucaccuuca aaguccucga ccucaagaac uacauagaua aacaacuacu ccccauccua      600

aacaaacagu caugcagcau auccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaccgccucc uugaaaucac ccgcgaguuc ucugucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucacaaa cuccgaacuc cucagccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgucaaca aucauacuca      840

aucaugugca ucauuaaaga agaaguccuc gcauacgucg uccaacuccc ccucuauggg      900

gucaucgaca ccccaugcug gaaacuccac accucucccc uaugcaccac caacaccaaa      960

gaaggcucca acaucugccu aacccgaacc gaccgcggau gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgaaaca uguaaagucu gcuccaaccg uguguucugc     1080

gacaccauga acucacuaac ccuccccucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aauaaugacc agcaaaacag acguauccuc uagcgucauu     1200

accagccuag gugcaaucgu guccugcuac ggcaaaacaa aaugcaccgc cuccaacaaa     1260

aauaaaggaa ucauaaaaac cuucuccaac ggcugcgacu acgucagcaa caaaggaguc     1320

gacaccgucu ccguaggaaa uacucuauac uaugucaaca aacaagaggg uaaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cucugacgag     1440

uucgacgcca gcauaucaca aguaaacgaa aagaucaacc aaucccucgc auucauucgc     1500

aaauccgacg aacuccuaca caacgucaac gccggaaaau ccaccaccaa caucaugauc     1560

acuacuauca uuaucgucau caucgucauc cuccucuccc ucaucgcagu cggccuucua     1620

cucuacugca aggcacgcuc uacacccgua acccugucua aagaccaacu cuccggcauc     1680

aacaacaucg cuuucuccaa cuaaggacua guacuggcug caucucccuu uccucugucc     1740

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1800

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1920

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1980

auu                                                                   1983


<210>  6915
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6915
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6916
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6916
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcuc caccccggug acccugagca aggaccagcu guccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6917
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6917
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6918
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6918
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacgguc uacaccggug accuugagca aagaccagcu guccggcauc     1680

aacaauauag cuuucucaaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6919
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6919
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6920
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6920
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcuc cacaccugug acccugagca aagaccagcu uucugggauc     1680

aacaauauug cguucuccaa cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6921
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6921
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acucaaagca      120

aaugcaauua ccacuauacu cacagcugua acuuuuuguu ucgccucagg acaaaacauc      180

acagaagaau uuuaucaauc cacaugcucu gccguaucaa aaggcuaccu aucugcccua      240

agaacagguu gguacacauc uguaauaaca aucgaauuau ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaaacaag aauuagauaa auauaaaaac      360

gcaguaacag aacuacaaau gcuaaugugc ucuacacccg ccacaggauc aggauccgca      420

aucgcuucug gaguagccgu uugcaaagua uuacaccuag aaggagaagu aaauaaaaua      480

aaauccgcac uacuaucaac uaauaaagca guaguaucac uuucuaaugg uguaucagua      540

uuaacauuca aaguccucga ccuaaaaaau uacaucgaca aacaacuauu acccauccuu      600

aauaaacaau caugcuccau aucaaacaua gaaacuguca uggaauuuca acaaaaaaac      660

aauagacuuc uagaaaucac aagagaauuu ucuguaaaug caggaguaac uacaccagua      720

ucaacauaua uguuaaccaa cuccgaacua cuaucacuca uaaacgacau gccaauaaca      780

aacgaccaaa aaaaacuaau gucaaauaac guucaaauag uaagacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguuuua gcauacgucg uacaacuucc ccuauacgga      900

guaauagaca ccccuugcug gaaacuccac accucaccac uaugcacuac aaacacaaaa      960

gaagguucca acaucugcuu aacaagaacc gaucgaggau gguacugcga caacgcuggu     1020

uccguaucuu ucuucccaca agcagaaaca ugcaaaguau gcuccaauag aguauucugc     1080

gacaccauga acucacuaac ucuaccaucc gaaguaaacc uaugcaacgu cgacauauuu     1140

aauccaaaau augacugcaa aauaaugacu ucaaaaacag acguauccuc aucaguaaua     1200

acauccuuag gagcaauagu aucauguuac ggcaagacaa aauguacagc cucaaacaaa     1260

aacaaaggua ucauuaaaac cuucuccaac ggcugcgacu acguaucaaa uaaagguguc     1320

gauacaguau caguaggaaa cacacucuau uacguuaaua aacaagaagg aaagucauua     1380

uacguaaaag gagaaccaau aaucaauuuc uacgaucccc uagucuuucc cucagaugaa     1440

uuugacgcaa gcaucucuca agucaacgaa aaaauaaacc aaucccuagc cuucauaaga     1500

aaaucagaug aacuacuuca uaacgucaac gccggaaaau caacaaccaa cauaaugauc     1560

acuacaauca uaauuguaau uauaguaaua cuacuaucgc uaauugccgu uggacuacua     1620

cuauauugua aagcaagauc aacacccguu acucuaucca aagaucaauu aucaggaauc     1680

aacaacauag ccuucucaaa uuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6922
<211>  1979
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6922
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuuaaagcc      120

aacgcaauaa ccacaauccu caccgccguc acauucugcu ucgccucggg acaaaacaua      180

accgaagaau uuuaccaguc uaccugcucc gccgucucca aggguuaccu cuccgcgcuc      240

cgcaccgggu gguacaccag cguuaucacc aucgaacuau cuaacauaaa agaaaacaag      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaagaau      360

gccgucaccg aacuacaaau gcucaugugc uccacccccg ccaccggauc cggcuccgcc      420

auugccuccg gcgucgccgu augcaaaguc cuucacuugg aaggagaagu uaacaaaaua      480

aaaagcgccc uccugucgac caacaaagcg guggucagcc ucuccaacgg cgucucuguc      540

cucaccuuca aaguccucga ccucaagaac uacauagaua aacaacuacu ccccauccua      600

aacaaacagu caugcagcau auccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaccgccucc uugaaaucac ccgcgaguuc ucugucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucacaaa cuccgaacuc cucagccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgucaaca aucauacuca      840

aucaugugca ucauuaaaga agaaguccuc gcauacgucg uccaacuccc ccucuauggg      900

gucaucgaca ccccaugcug gaaacuccac accucucccc uaugcaccac caacaccaaa      960

gaaggcucca acaucugccu aacccgaacc gaccgcggau gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgaaaca uguaaagucu gcuccaaccg uguguucugc     1080

gacaccauga acucacuaac ccuccccucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aauaaugacc agcaaaacag acguauccuc uagcgucauu     1200

accagccuag gugcaaucgu guccugcuac ggcaaaacaa aaugcaccgc cuccaacaaa     1260

aauaaaggaa ucauaaaaac cuucuccaac ggcugcgacu acgucagcaa caaaggaguc     1320

gacaccgucu ccguaggaaa uacucuauac uaugucaaca aacaagaggg uaaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cucugacgag     1440

uucgacgcca gcauaucaca aguaaacgaa aagaucaacc aaucccucgc auucauucgc     1500

aaauccgacg aacuccuaca caacgucaac gccggaaaau ccaccaccaa caucaugauc     1560

acuacuauca uuaucgucau caucgucauc cuccucuccc ucaucgcagu cggccuucua     1620

cucuacugca aggcacgcuc uacacccgua acccugucua aagaccaacu cuccggcauc     1680

aacaacaucg cuuucuccaa cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1740

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1800

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1920

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1979


<210>  6923
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6923
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6924
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6924
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcuccacccc ggugacccug agcaaggacc agcuguccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6925
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6925
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6926
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6926
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggucuacacc ggugaccuug agcaaagacc agcuguccgg caucaacaau     1680

auagcuuucu caaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6927
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6927
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6928
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6928
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcuccacacc ugugacccug agcaaagacc agcuuucugg gaucaacaau     1680

auugcguucu ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6929
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6929
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacucaa agcaaaugca      120

auuaccacua uacucacagc uguaacuuuu uguuucgccu caggacaaaa caucacagaa      180

gaauuuuauc aauccacaug cucugccgua ucaaaaggcu accuaucugc ccuaagaaca      240

gguugguaca caucuguaau aacaaucgaa uuauccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaaa caagaauuag auaaauauaa aaacgcagua      360

acagaacuac aaaugcuaau gugcucuaca cccgccacag gaucaggauc cgcaaucgcu      420

ucuggaguag ccguuugcaa aguauuacac cuagaaggag aaguaaauaa aauaaaaucc      480

gcacuacuau caacuaauaa agcaguagua ucacuuucua augguguauc aguauuaaca      540

uucaaagucc ucgaccuaaa aaauuacauc gacaaacaac uauuacccau ccuuaauaaa      600

caaucaugcu ccauaucaaa cauagaaacu gucauggaau uucaacaaaa aaacaauaga      660

cuucuagaaa ucacaagaga auuuucugua aaugcaggag uaacuacacc aguaucaaca      720

uauauguuaa ccaacuccga acuacuauca cucauaaacg acaugccaau aacaaacgac      780

caaaaaaaac uaaugucaaa uaacguucaa auaguaagac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu uuuagcauac gucguacaac uuccccuaua cggaguaaua      900

gacaccccuu gcuggaaacu ccacaccuca ccacuaugca cuacaaacac aaaagaaggu      960

uccaacaucu gcuuaacaag aaccgaucga ggaugguacu gcgacaacgc ugguuccgua     1020

ucuuucuucc cacaagcaga aacaugcaaa guaugcucca auagaguauu cugcgacacc     1080

augaacucac uaacucuacc auccgaagua aaccuaugca acgucgacau auuuaaucca     1140

aaauaugacu gcaaaauaau gacuucaaaa acagacguau ccucaucagu aauaacaucc     1200

uuaggagcaa uaguaucaug uuacggcaag acaaaaugua cagccucaaa caaaaacaaa     1260

gguaucauua aaaccuucuc caacggcugc gacuacguau caaauaaagg ugucgauaca     1320

guaucaguag gaaacacacu cuauuacguu aauaaacaag aaggaaaguc auuauacgua     1380

aaaggagaac caauaaucaa uuucuacgau ccccuagucu uucccucaga ugaauuugac     1440

gcaagcaucu cucaagucaa cgaaaaaaua aaccaauccc uagccuucau aagaaaauca     1500

gaugaacuac uucauaacgu caacgccgga aaaucaacaa ccaacauaau gaucacuaca     1560

aucauaauug uaauuauagu aauacuacua ucgcuaauug ccguuggacu acuacuauau     1620

uguaaagcaa gaucaacacc cguuacucua uccaaagauc aauuaucagg aaucaacaac     1680

auagccuucu caaauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6930
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6930
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuuaa agccaacgca      120

auaaccacaa uccucaccgc cgucacauuc ugcuucgccu cgggacaaaa cauaaccgaa      180

gaauuuuacc agucuaccug cuccgccguc uccaaggguu accucuccgc gcuccgcacc      240

gggugguaca ccagcguuau caccaucgaa cuaucuaaca uaaaagaaaa caagugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa gaaugccguc      360

accgaacuac aaaugcucau gugcuccacc cccgccaccg gauccggcuc cgccauugcc      420

uccggcgucg ccguaugcaa aguccuucac uuggaaggag aaguuaacaa aauaaaaagc      480

gcccuccugu cgaccaacaa agcggugguc agccucucca acggcgucuc uguccucacc      540

uucaaagucc ucgaccucaa gaacuacaua gauaaacaac uacuccccau ccuaaacaaa      600

cagucaugca gcauauccaa caucgaaacc gucauggagu uccaacagaa aaacaaccgc      660

cuccuugaaa ucacccgcga guucucuguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca caaacuccga acuccucagc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucguc aacaaucaua cucaaucaug      840

ugcaucauua aagaagaagu ccucgcauac gucguccaac ucccccucua uggggucauc      900

gacaccccau gcuggaaacu ccacaccucu ccccuaugca ccaccaacac caaagaaggc      960

uccaacaucu gccuaacccg aaccgaccgc ggaugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga aacauguaaa gucugcucca accguguguu cugcgacacc     1080

augaacucac uaacccuccc cuccgaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaauaau gaccagcaaa acagacguau ccucuagcgu cauuaccagc     1200

cuaggugcaa ucguguccug cuacggcaaa acaaaaugca ccgccuccaa caaaaauaaa     1260

ggaaucauaa aaaccuucuc caacggcugc gacuacguca gcaacaaagg agucgacacc     1320

gucuccguag gaaauacucu auacuauguc aacaaacaag aggguaaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccucuga cgaguucgac     1440

gccagcauau cacaaguaaa cgaaaagauc aaccaauccc ucgcauucau ucgcaaaucc     1500

gacgaacucc uacacaacgu caacgccgga aaauccacca ccaacaucau gaucacuacu     1560

aucauuaucg ucaucaucgu cauccuccuc ucccucaucg cagucggccu ucuacucuac     1620

ugcaaggcac gcucuacacc cguaacccug ucuaaagacc aacucuccgg caucaacaac     1680

aucgcuuucu ccaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1740

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  6931
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6931
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6932
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6932
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cuccaccccg gugacccuga gcaaggacca gcuguccggg     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6933
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6933
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6934
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6934
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gucuacaccg gugaccuuga gcaaagacca gcuguccggc     1680

aucaacaaua uagcuuucuc aaacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6935
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6935
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6936
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6936
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cuccacaccu gugacccuga gcaaagacca gcuuucuggg     1680

aucaacaaua uugcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6937
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6937
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacucaaa      120

gcaaaugcaa uuaccacuau acucacagcu guaacuuuuu guuucgccuc aggacaaaac      180

aucacagaag aauuuuauca auccacaugc ucugccguau caaaaggcua ccuaucugcc      240

cuaagaacag guugguacac aucuguaaua acaaucgaau uauccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaaac aagaauuaga uaaauauaaa      360

aacgcaguaa cagaacuaca aaugcuaaug ugcucuacac ccgccacagg aucaggaucc      420

gcaaucgcuu cuggaguagc cguuugcaaa guauuacacc uagaaggaga aguaaauaaa      480

auaaaauccg cacuacuauc aacuaauaaa gcaguaguau cacuuucuaa ugguguauca      540

guauuaacau ucaaaguccu cgaccuaaaa aauuacaucg acaaacaacu auuacccauc      600

cuuaauaaac aaucaugcuc cauaucaaac auagaaacug ucauggaauu ucaacaaaaa      660

aacaauagac uucuagaaau cacaagagaa uuuucuguaa augcaggagu aacuacacca      720

guaucaacau auauguuaac caacuccgaa cuacuaucac ucauaaacga caugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguucaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguu uuagcauacg ucguacaacu uccccuauac      900

ggaguaauag acaccccuug cuggaaacuc cacaccucac cacuaugcac uacaaacaca      960

aaagaagguu ccaacaucug cuuaacaaga accgaucgag gaugguacug cgacaacgcu     1020

gguuccguau cuuucuuccc acaagcagaa acaugcaaag uaugcuccaa uagaguauuc     1080

ugcgacacca ugaacucacu aacucuacca uccgaaguaa accuaugcaa cgucgacaua     1140

uuuaauccaa aauaugacug caaaauaaug acuucaaaaa cagacguauc cucaucagua     1200

auaacauccu uaggagcaau aguaucaugu uacggcaaga caaaauguac agccucaaac     1260

aaaaacaaag guaucauuaa aaccuucucc aacggcugcg acuacguauc aaauaaaggu     1320

gucgauacag uaucaguagg aaacacacuc uauuacguua auaaacaaga aggaaaguca     1380

uuauacguaa aaggagaacc aauaaucaau uucuacgauc cccuagucuu ucccucagau     1440

gaauuugacg caagcaucuc ucaagucaac gaaaaaauaa accaaucccu agccuucaua     1500

agaaaaucag augaacuacu ucauaacguc aacgccggaa aaucaacaac caacauaaug     1560

aucacuacaa ucauaauugu aauuauagua auacuacuau cgcuaauugc cguuggacua     1620

cuacuauauu guaaagcaag aucaacaccc guuacucuau ccaaagauca auuaucagga     1680

aucaacaaca uagccuucuc aaauuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6938
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6938
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuuaaa      120

gccaacgcaa uaaccacaau ccucaccgcc gucacauucu gcuucgccuc gggacaaaac      180

auaaccgaag aauuuuacca gucuaccugc uccgccgucu ccaaggguua ccucuccgcg      240

cuccgcaccg ggugguacac cagcguuauc accaucgaac uaucuaacau aaaagaaaac      300

aagugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaag      360

aaugccguca ccgaacuaca aaugcucaug ugcuccaccc ccgccaccgg auccggcucc      420

gccauugccu ccggcgucgc cguaugcaaa guccuucacu uggaaggaga aguuaacaaa      480

auaaaaagcg cccuccuguc gaccaacaaa gcggugguca gccucuccaa cggcgucucu      540

guccucaccu ucaaaguccu cgaccucaag aacuacauag auaaacaacu acuccccauc      600

cuaaacaaac agucaugcag cauauccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaccgcc uccuugaaau cacccgcgag uucucuguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucguca acaaucauac      840

ucaaucaugu gcaucauuaa agaagaaguc cucgcauacg ucguccaacu cccccucuau      900

ggggucaucg acaccccaug cuggaaacuc cacaccucuc cccuaugcac caccaacacc      960

aaagaaggcu ccaacaucug ccuaacccga accgaccgcg gaugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgaa acauguaaag ucugcuccaa ccguguguuc     1080

ugcgacacca ugaacucacu aacccucccc uccgaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaauaaug accagcaaaa cagacguauc cucuagcguc     1200

auuaccagcc uaggugcaau cguguccugc uacggcaaaa caaaaugcac cgccuccaac     1260

aaaaauaaag gaaucauaaa aaccuucucc aacggcugcg acuacgucag caacaaagga     1320

gucgacaccg ucuccguagg aaauacucua uacuauguca acaaacaaga ggguaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccucugac     1440

gaguucgacg ccagcauauc acaaguaaac gaaaagauca accaaucccu cgcauucauu     1500

cgcaaauccg acgaacuccu acacaacguc aacgccggaa aauccaccac caacaucaug     1560

aucacuacua ucauuaucgu caucaucguc auccuccucu cccucaucgc agucggccuu     1620

cuacucuacu gcaaggcacg cucuacaccc guaacccugu cuaaagacca acucuccggc     1680

aucaacaaca ucgcuuucuc caacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  6939
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6939
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6940
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6940
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcuccacccc ggugacccug agcaaggacc agcuguccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6941
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6941
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6942
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6942
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggucuacacc ggugaccuug agcaaagacc agcuguccgg caucaacaau     1680

auagcuuucu caaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6943
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6943
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6944
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6944
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcuccacacc ugugacccug agcaaagacc agcuuucugg gaucaacaau     1680

auugcguucu ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6945
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6945
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacucaa agcaaaugca      120

auuaccacua uacucacagc uguaacuuuu uguuucgccu caggacaaaa caucacagaa      180

gaauuuuauc aauccacaug cucugccgua ucaaaaggcu accuaucugc ccuaagaaca      240

gguugguaca caucuguaau aacaaucgaa uuauccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaaa caagaauuag auaaauauaa aaacgcagua      360

acagaacuac aaaugcuaau gugcucuaca cccgccacag gaucaggauc cgcaaucgcu      420

ucuggaguag ccguuugcaa aguauuacac cuagaaggag aaguaaauaa aauaaaaucc      480

gcacuacuau caacuaauaa agcaguagua ucacuuucua augguguauc aguauuaaca      540

uucaaagucc ucgaccuaaa aaauuacauc gacaaacaac uauuacccau ccuuaauaaa      600

caaucaugcu ccauaucaaa cauagaaacu gucauggaau uucaacaaaa aaacaauaga      660

cuucuagaaa ucacaagaga auuuucugua aaugcaggag uaacuacacc aguaucaaca      720

uauauguuaa ccaacuccga acuacuauca cucauaaacg acaugccaau aacaaacgac      780

caaaaaaaac uaaugucaaa uaacguucaa auaguaagac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu uuuagcauac gucguacaac uuccccuaua cggaguaaua      900

gacaccccuu gcuggaaacu ccacaccuca ccacuaugca cuacaaacac aaaagaaggu      960

uccaacaucu gcuuaacaag aaccgaucga ggaugguacu gcgacaacgc ugguuccgua     1020

ucuuucuucc cacaagcaga aacaugcaaa guaugcucca auagaguauu cugcgacacc     1080

augaacucac uaacucuacc auccgaagua aaccuaugca acgucgacau auuuaaucca     1140

aaauaugacu gcaaaauaau gacuucaaaa acagacguau ccucaucagu aauaacaucc     1200

uuaggagcaa uaguaucaug uuacggcaag acaaaaugua cagccucaaa caaaaacaaa     1260

gguaucauua aaaccuucuc caacggcugc gacuacguau caaauaaagg ugucgauaca     1320

guaucaguag gaaacacacu cuauuacguu aauaaacaag aaggaaaguc auuauacgua     1380

aaaggagaac caauaaucaa uuucuacgau ccccuagucu uucccucaga ugaauuugac     1440

gcaagcaucu cucaagucaa cgaaaaaaua aaccaauccc uagccuucau aagaaaauca     1500

gaugaacuac uucauaacgu caacgccgga aaaucaacaa ccaacauaau gaucacuaca     1560

aucauaauug uaauuauagu aauacuacua ucgcuaauug ccguuggacu acuacuauau     1620

uguaaagcaa gaucaacacc cguuacucua uccaaagauc aauuaucagg aaucaacaac     1680

auagccuucu caaauuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6946
<211>  1961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6946
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuuaa agccaacgca      120

auaaccacaa uccucaccgc cgucacauuc ugcuucgccu cgggacaaaa cauaaccgaa      180

gaauuuuacc agucuaccug cuccgccguc uccaaggguu accucuccgc gcuccgcacc      240

gggugguaca ccagcguuau caccaucgaa cuaucuaaca uaaaagaaaa caagugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa gaaugccguc      360

accgaacuac aaaugcucau gugcuccacc cccgccaccg gauccggcuc cgccauugcc      420

uccggcgucg ccguaugcaa aguccuucac uuggaaggag aaguuaacaa aauaaaaagc      480

gcccuccugu cgaccaacaa agcggugguc agccucucca acggcgucuc uguccucacc      540

uucaaagucc ucgaccucaa gaacuacaua gauaaacaac uacuccccau ccuaaacaaa      600

cagucaugca gcauauccaa caucgaaacc gucauggagu uccaacagaa aaacaaccgc      660

cuccuugaaa ucacccgcga guucucuguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca caaacuccga acuccucagc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucguc aacaaucaua cucaaucaug      840

ugcaucauua aagaagaagu ccucgcauac gucguccaac ucccccucua uggggucauc      900

gacaccccau gcuggaaacu ccacaccucu ccccuaugca ccaccaacac caaagaaggc      960

uccaacaucu gccuaacccg aaccgaccgc ggaugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga aacauguaaa gucugcucca accguguguu cugcgacacc     1080

augaacucac uaacccuccc cuccgaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaauaau gaccagcaaa acagacguau ccucuagcgu cauuaccagc     1200

cuaggugcaa ucguguccug cuacggcaaa acaaaaugca ccgccuccaa caaaaauaaa     1260

ggaaucauaa aaaccuucuc caacggcugc gacuacguca gcaacaaagg agucgacacc     1320

gucuccguag gaaauacucu auacuauguc aacaaacaag aggguaaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccucuga cgaguucgac     1440

gccagcauau cacaaguaaa cgaaaagauc aaccaauccc ucgcauucau ucgcaaaucc     1500

gacgaacucc uacacaacgu caacgccgga aaauccacca ccaacaucau gaucacuacu     1560

aucauuaucg ucaucaucgu cauccuccuc ucccucaucg cagucggccu ucuacucuac     1620

ugcaaggcac gcucuacacc cguaacccug ucuaaagacc aacucuccgg caucaacaac     1680

aucgcuuucu ccaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1740

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1800

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1920

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1961


<210>  6947
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6947
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6948
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6948
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcucca ccccggugac ccugagcaag     1740

gaccagcugu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6949
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6949
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6950
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6950
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggucua caccggugac cuugagcaaa     1740

gaccagcugu ccggcaucaa caauauagcu uucucaaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6951
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6951
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6952
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6952
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcucca caccugugac ccugagcaaa     1740

gaccagcuuu cugggaucaa caauauugcg uucuccaacu gaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6953
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6953
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac ucaaagcaaa ugcaauuacc acuauacuca cagcuguaac uuuuuguuuc      240

gccucaggac aaaacaucac agaagaauuu uaucaaucca caugcucugc cguaucaaaa      300

ggcuaccuau cugcccuaag aacagguugg uacacaucug uaauaacaau cgaauuaucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caaacaagaa      420

uuagauaaau auaaaaacgc aguaacagaa cuacaaaugc uaaugugcuc uacacccgcc      480

acaggaucag gauccgcaau cgcuucugga guagccguuu gcaaaguauu acaccuagaa      540

ggagaaguaa auaaaauaaa auccgcacua cuaucaacua auaaagcagu aguaucacuu      600

ucuaauggug uaucaguauu aacauucaaa guccucgacc uaaaaaauua caucgacaaa      660

caacuauuac ccauccuuaa uaaacaauca ugcuccauau caaacauaga aacugucaug      720

gaauuucaac aaaaaaacaa uagacuucua gaaaucacaa gagaauuuuc uguaaaugca      780

ggaguaacua caccaguauc aacauauaug uuaaccaacu ccgaacuacu aucacucaua      840

aacgacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu ucaaauagua      900

agacaacaau cauacucaau caugugcaua auaaaagaag aaguuuuagc auacgucgua      960

caacuucccc uauacggagu aauagacacc ccuugcugga aacuccacac cucaccacua     1020

ugcacuacaa acacaaaaga agguuccaac aucugcuuaa caagaaccga ucgaggaugg     1080

uacugcgaca acgcugguuc cguaucuuuc uucccacaag cagaaacaug caaaguaugc     1140

uccaauagag uauucugcga caccaugaac ucacuaacuc uaccauccga aguaaaccua     1200

ugcaacgucg acauauuuaa uccaaaauau gacugcaaaa uaaugacuuc aaaaacagac     1260

guauccucau caguaauaac auccuuagga gcaauaguau cauguuacgg caagacaaaa     1320

uguacagccu caaacaaaaa caaagguauc auuaaaaccu ucuccaacgg cugcgacuac     1380

guaucaaaua aaggugucga uacaguauca guaggaaaca cacucuauua cguuaauaaa     1440

caagaaggaa agucauuaua cguaaaagga gaaccaauaa ucaauuucua cgauccccua     1500

gucuuucccu cagaugaauu ugacgcaagc aucucucaag ucaacgaaaa aauaaaccaa     1560

ucccuagccu ucauaagaaa aucagaugaa cuacuucaua acgucaacgc cggaaaauca     1620

acaaccaaca uaaugaucac uacaaucaua auuguaauua uaguaauacu acuaucgcua     1680

auugccguug gacuacuacu auauuguaaa gcaagaucaa cacccguuac ucuauccaaa     1740

gaucaauuau caggaaucaa caacauagcc uucucaaauu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6954
<211>  2277
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6954
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uuaaagccaa cgcaauaacc acaauccuca ccgccgucac auucugcuuc      240

gccucgggac aaaacauaac cgaagaauuu uaccagucua ccugcuccgc cgucuccaag      300

gguuaccucu ccgcgcuccg caccgggugg uacaccagcg uuaucaccau cgaacuaucu      360

aacauaaaag aaaacaagug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaagaaugc cgucaccgaa cuacaaaugc ucaugugcuc cacccccgcc      480

accggauccg gcuccgccau ugccuccggc gucgccguau gcaaaguccu ucacuuggaa      540

ggagaaguua acaaaauaaa aagcgcccuc cugucgacca acaaagcggu ggucagccuc      600

uccaacggcg ucucuguccu caccuucaaa guccucgacc ucaagaacua cauagauaaa      660

caacuacucc ccauccuaaa caaacaguca ugcagcauau ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ccgccuccuu gaaaucaccc gcgaguucuc ugucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucacaaacu ccgaacuccu cagccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgucaacaau cauacucaau caugugcauc auuaaagaag aaguccucgc auacgucguc      960

caacuccccc ucuauggggu caucgacacc ccaugcugga aacuccacac cucuccccua     1020

ugcaccacca acaccaaaga aggcuccaac aucugccuaa cccgaaccga ccgcggaugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgaaacaug uaaagucugc     1140

uccaaccgug uguucugcga caccaugaac ucacuaaccc uccccuccga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa uaaugaccag caaaacagac     1260

guauccucua gcgucauuac cagccuaggu gcaaucgugu ccugcuacgg caaaacaaaa     1320

ugcaccgccu ccaacaaaaa uaaaggaauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucagcaaca aaggagucga caccgucucc guaggaaaua cucuauacua ugucaacaaa     1440

caagagggua aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu cugacgaguu cgacgccagc auaucacaag uaaacgaaaa gaucaaccaa     1560

ucccucgcau ucauucgcaa auccgacgaa cuccuacaca acgucaacgc cggaaaaucc     1620

accaccaaca ucaugaucac uacuaucauu aucgucauca ucgucauccu ccucucccuc     1680

aucgcagucg gccuucuacu cuacugcaag gcacgcucua cacccguaac ccugucuaaa     1740

gaccaacucu ccggcaucaa caacaucgcu uucuccaacu aaggacuagu gaagggaaca     1800

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1860

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1920

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1980

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     2040

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2100

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2220

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2277


<210>  6955
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6955
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6956
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6956
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

ccaccccggu gacccugagc aaggaccagc uguccgggau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6957
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6957
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6958
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6958
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

cuacaccggu gaccuugagc aaagaccagc uguccggcau caacaauaua gcuuucucaa     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6959
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6959
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6960
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6960
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

ccacaccugu gacccugagc aaagaccagc uuucugggau caacaauauu gcguucucca     1680

acugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6961
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6961
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacucaaagc aaaugcaauu accacuauac      120

ucacagcugu aacuuuuugu uucgccucag gacaaaacau cacagaagaa uuuuaucaau      180

ccacaugcuc ugccguauca aaaggcuacc uaucugcccu aagaacaggu ugguacacau      240

cuguaauaac aaucgaauua uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaaacaa gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa      360

ugcuaaugug cucuacaccc gccacaggau caggauccgc aaucgcuucu ggaguagccg      420

uuugcaaagu auuacaccua gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa      480

cuaauaaagc aguaguauca cuuucuaaug guguaucagu auuaacauuc aaaguccucg      540

accuaaaaaa uuacaucgac aaacaacuau uacccauccu uaauaaacaa ucaugcucca      600

uaucaaacau agaaacuguc auggaauuuc aacaaaaaaa caauagacuu cuagaaauca      660

caagagaauu uucuguaaau gcaggaguaa cuacaccagu aucaacauau auguuaacca      720

acuccgaacu acuaucacuc auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa      780

ugucaaauaa cguucaaaua guaagacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguuuu agcauacguc guacaacuuc cccuauacgg aguaauagac accccuugcu      900

ggaaacucca caccucacca cuaugcacua caaacacaaa agaagguucc aacaucugcu      960

uaacaagaac cgaucgagga ugguacugcg acaacgcugg uuccguaucu uucuucccac     1020

aagcagaaac augcaaagua ugcuccaaua gaguauucug cgacaccaug aacucacuaa     1080

cucuaccauc cgaaguaaac cuaugcaacg ucgacauauu uaauccaaaa uaugacugca     1140

aaauaaugac uucaaaaaca gacguauccu caucaguaau aacauccuua ggagcaauag     1200

uaucauguua cggcaagaca aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa     1260

ccuucuccaa cggcugcgac uacguaucaa auaaaggugu cgauacagua ucaguaggaa     1320

acacacucua uuacguuaau aaacaagaag gaaagucauu auacguaaaa ggagaaccaa     1380

uaaucaauuu cuacgauccc cuagucuuuc ccucagauga auuugacgca agcaucucuc     1440

aagucaacga aaaaauaaac caaucccuag ccuucauaag aaaaucagau gaacuacuuc     1500

auaacgucaa cgccggaaaa ucaacaacca acauaaugau cacuacaauc auaauuguaa     1560

uuauaguaau acuacuaucg cuaauugccg uuggacuacu acuauauugu aaagcaagau     1620

caacacccgu uacucuaucc aaagaucaau uaucaggaau caacaacaua gccuucucaa     1680

auuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6962
<211>  1960
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6962
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuuaaagc caacgcaaua accacaaucc      120

ucaccgccgu cacauucugc uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu      180

cuaccugcuc cgccgucucc aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca      240

gcguuaucac caucgaacua ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaagaa ugccgucacc gaacuacaaa      360

ugcucaugug cuccaccccc gccaccggau ccggcuccgc cauugccucc ggcgucgccg      420

uaugcaaagu ccuucacuug gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga      480

ccaacaaagc gguggucagc cucuccaacg gcgucucugu ccucaccuuc aaaguccucg      540

accucaagaa cuacauagau aaacaacuac uccccauccu aaacaaacag ucaugcagca      600

uauccaacau cgaaaccguc auggaguucc aacagaaaaa caaccgccuc cuugaaauca      660

cccgcgaguu cucugucaac gccggcguca ccacccccgu cuccaccuac augcucacaa      720

acuccgaacu ccucagccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgucaac aaucauacuc aaucaugugc aucauuaaag      840

aagaaguccu cgcauacguc guccaacucc cccucuaugg ggucaucgac accccaugcu      900

ggaaacucca caccucuccc cuaugcacca ccaacaccaa agaaggcucc aacaucugcc      960

uaacccgaac cgaccgcgga ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgaaac auguaaaguc ugcuccaacc guguguucug cgacaccaug aacucacuaa     1080

cccuccccuc cgaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaauaaugac cagcaaaaca gacguauccu cuagcgucau uaccagccua ggugcaaucg     1200

uguccugcua cggcaaaaca aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa     1260

ccuucuccaa cggcugcgac uacgucagca acaaaggagu cgacaccguc uccguaggaa     1320

auacucuaua cuaugucaac aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccucugacga guucgacgcc agcauaucac     1440

aaguaaacga aaagaucaac caaucccucg cauucauucg caaauccgac gaacuccuac     1500

acaacgucaa cgccggaaaa uccaccacca acaucaugau cacuacuauc auuaucguca     1560

ucaucgucau ccuccucucc cucaucgcag ucggccuucu acucuacugc aaggcacgcu     1620

cuacacccgu aacccugucu aaagaccaac ucuccggcau caacaacauc gcuuucucca     1680

acuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1740

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1800

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1920

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1960


<210>  6963
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6963
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6964
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6964
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcucca ccccggugac ccugagcaag     1740

gaccagcugu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6965
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6965
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6966
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6966
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggucua caccggugac cuugagcaaa     1740

gaccagcugu ccggcaucaa caauauagcu uucucaaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6967
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6967
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6968
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6968
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcucca caccugugac ccugagcaaa     1740

gaccagcuuu cugggaucaa caauauugcg uucuccaacu gaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6969
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6969
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac ucaaagcaaa ugcaauuacc acuauacuca cagcuguaac uuuuuguuuc      240

gccucaggac aaaacaucac agaagaauuu uaucaaucca caugcucugc cguaucaaaa      300

ggcuaccuau cugcccuaag aacagguugg uacacaucug uaauaacaau cgaauuaucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caaacaagaa      420

uuagauaaau auaaaaacgc aguaacagaa cuacaaaugc uaaugugcuc uacacccgcc      480

acaggaucag gauccgcaau cgcuucugga guagccguuu gcaaaguauu acaccuagaa      540

ggagaaguaa auaaaauaaa auccgcacua cuaucaacua auaaagcagu aguaucacuu      600

ucuaauggug uaucaguauu aacauucaaa guccucgacc uaaaaaauua caucgacaaa      660

caacuauuac ccauccuuaa uaaacaauca ugcuccauau caaacauaga aacugucaug      720

gaauuucaac aaaaaaacaa uagacuucua gaaaucacaa gagaauuuuc uguaaaugca      780

ggaguaacua caccaguauc aacauauaug uuaaccaacu ccgaacuacu aucacucaua      840

aacgacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu ucaaauagua      900

agacaacaau cauacucaau caugugcaua auaaaagaag aaguuuuagc auacgucgua      960

caacuucccc uauacggagu aauagacacc ccuugcugga aacuccacac cucaccacua     1020

ugcacuacaa acacaaaaga agguuccaac aucugcuuaa caagaaccga ucgaggaugg     1080

uacugcgaca acgcugguuc cguaucuuuc uucccacaag cagaaacaug caaaguaugc     1140

uccaauagag uauucugcga caccaugaac ucacuaacuc uaccauccga aguaaaccua     1200

ugcaacgucg acauauuuaa uccaaaauau gacugcaaaa uaaugacuuc aaaaacagac     1260

guauccucau caguaauaac auccuuagga gcaauaguau cauguuacgg caagacaaaa     1320

uguacagccu caaacaaaaa caaagguauc auuaaaaccu ucuccaacgg cugcgacuac     1380

guaucaaaua aaggugucga uacaguauca guaggaaaca cacucuauua cguuaauaaa     1440

caagaaggaa agucauuaua cguaaaagga gaaccaauaa ucaauuucua cgauccccua     1500

gucuuucccu cagaugaauu ugacgcaagc aucucucaag ucaacgaaaa aauaaaccaa     1560

ucccuagccu ucauaagaaa aucagaugaa cuacuucaua acgucaacgc cggaaaauca     1620

acaaccaaca uaaugaucac uacaaucaua auuguaauua uaguaauacu acuaucgcua     1680

auugccguug gacuacuacu auauuguaaa gcaagaucaa cacccguuac ucuauccaaa     1740

gaucaauuau caggaaucaa caacauagcc uucucaaauu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6970
<211>  2057
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6970
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uuaaagccaa cgcaauaacc acaauccuca ccgccgucac auucugcuuc      240

gccucgggac aaaacauaac cgaagaauuu uaccagucua ccugcuccgc cgucuccaag      300

gguuaccucu ccgcgcuccg caccgggugg uacaccagcg uuaucaccau cgaacuaucu      360

aacauaaaag aaaacaagug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaagaaugc cgucaccgaa cuacaaaugc ucaugugcuc cacccccgcc      480

accggauccg gcuccgccau ugccuccggc gucgccguau gcaaaguccu ucacuuggaa      540

ggagaaguua acaaaauaaa aagcgcccuc cugucgacca acaaagcggu ggucagccuc      600

uccaacggcg ucucuguccu caccuucaaa guccucgacc ucaagaacua cauagauaaa      660

caacuacucc ccauccuaaa caaacaguca ugcagcauau ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ccgccuccuu gaaaucaccc gcgaguucuc ugucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucacaaacu ccgaacuccu cagccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgucaacaau cauacucaau caugugcauc auuaaagaag aaguccucgc auacgucguc      960

caacuccccc ucuauggggu caucgacacc ccaugcugga aacuccacac cucuccccua     1020

ugcaccacca acaccaaaga aggcuccaac aucugccuaa cccgaaccga ccgcggaugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgaaacaug uaaagucugc     1140

uccaaccgug uguucugcga caccaugaac ucacuaaccc uccccuccga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa uaaugaccag caaaacagac     1260

guauccucua gcgucauuac cagccuaggu gcaaucgugu ccugcuacgg caaaacaaaa     1320

ugcaccgccu ccaacaaaaa uaaaggaauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucagcaaca aaggagucga caccgucucc guaggaaaua cucuauacua ugucaacaaa     1440

caagagggua aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu cugacgaguu cgacgccagc auaucacaag uaaacgaaaa gaucaaccaa     1560

ucccucgcau ucauucgcaa auccgacgaa cuccuacaca acgucaacgc cggaaaaucc     1620

accaccaaca ucaugaucac uacuaucauu aucgucauca ucgucauccu ccucucccuc     1680

aucgcagucg gccuucuacu cuacugcaag gcacgcucua cacccguaac ccugucuaaa     1740

gaccaacucu ccggcaucaa caacaucgcu uucuccaacu aaggacuagu ggaagcauuu     1800

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1860

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1920

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2040

ucagagccac cagaauu                                                    2057


<210>  6971
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6971
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1680

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6972
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6972
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      420

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      480

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      540

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      600

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      720

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      960

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg     1020

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1080

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1140

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1260

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1320

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1380

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1620

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu ccaccccggu gacccugagc     1680

aaggaccagc uguccgggau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6973
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6973
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1680

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6974
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6974
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      420

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      480

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      540

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      600

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      660

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      720

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      780

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      840

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua      900

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca      960

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc     1020

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1080

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1140

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1200

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1260

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1320

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1380

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1440

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1500

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1560

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1620

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu cuacaccggu gaccuugagc     1680

aaagaccagc uguccggcau caacaauaua gcuuucucaa acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6975
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6975
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1680

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6976
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6976
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      420

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      480

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      540

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      600

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      660

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      720

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      780

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      840

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug      900

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu      960

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga     1020

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1080

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1140

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1200

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1260

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1320

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1380

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1440

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1500

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1560

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1620

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu ccacaccugu gacccugagc     1680

aaagaccagc uuucugggau caacaauauu gcguucucca acugaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6977
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6977
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaauuacuca uacucaaagc aaaugcaauu accacuauac ucacagcugu aacuuuuugu      180

uucgccucag gacaaaacau cacagaagaa uuuuaucaau ccacaugcuc ugccguauca      240

aaaggcuacc uaucugcccu aagaacaggu ugguacacau cuguaauaac aaucgaauua      300

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaaacaa      360

gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa ugcuaaugug cucuacaccc      420

gccacaggau caggauccgc aaucgcuucu ggaguagccg uuugcaaagu auuacaccua      480

gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa cuaauaaagc aguaguauca      540

cuuucuaaug guguaucagu auuaacauuc aaaguccucg accuaaaaaa uuacaucgac      600

aaacaacuau uacccauccu uaauaaacaa ucaugcucca uaucaaacau agaaacuguc      660

auggaauuuc aacaaaaaaa caauagacuu cuagaaauca caagagaauu uucuguaaau      720

gcaggaguaa cuacaccagu aucaacauau auguuaacca acuccgaacu acuaucacuc      780

auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguucaaaua      840

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguuuu agcauacguc      900

guacaacuuc cccuauacgg aguaauagac accccuugcu ggaaacucca caccucacca      960

cuaugcacua caaacacaaa agaagguucc aacaucugcu uaacaagaac cgaucgagga     1020

ugguacugcg acaacgcugg uuccguaucu uucuucccac aagcagaaac augcaaagua     1080

ugcuccaaua gaguauucug cgacaccaug aacucacuaa cucuaccauc cgaaguaaac     1140

cuaugcaacg ucgacauauu uaauccaaaa uaugacugca aaauaaugac uucaaaaaca     1200

gacguauccu caucaguaau aacauccuua ggagcaauag uaucauguua cggcaagaca     1260

aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa ccuucuccaa cggcugcgac     1320

uacguaucaa auaaaggugu cgauacagua ucaguaggaa acacacucua uuacguuaau     1380

aaacaagaag gaaagucauu auacguaaaa ggagaaccaa uaaucaauuu cuacgauccc     1440

cuagucuuuc ccucagauga auuugacgca agcaucucuc aagucaacga aaaaauaaac     1500

caaucccuag ccuucauaag aaaaucagau gaacuacuuc auaacgucaa cgccggaaaa     1560

ucaacaacca acauaaugau cacuacaauc auaauuguaa uuauaguaau acuacuaucg     1620

cuaauugccg uuggacuacu acuauauugu aaagcaagau caacacccgu uacucuaucc     1680

aaagaucaau uaucaggaau caacaacaua gccuucucaa auuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6978
<211>  1937
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6978
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuca uacuuaaagc caacgcaaua accacaaucc ucaccgccgu cacauucugc      180

uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu cuaccugcuc cgccgucucc      240

aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca gcguuaucac caucgaacua      300

ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa aagucaaacu caucaaacaa      360

gaacuagaca aauacaagaa ugccgucacc gaacuacaaa ugcucaugug cuccaccccc      420

gccaccggau ccggcuccgc cauugccucc ggcgucgccg uaugcaaagu ccuucacuug      480

gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga ccaacaaagc gguggucagc      540

cucuccaacg gcgucucugu ccucaccuuc aaaguccucg accucaagaa cuacauagau      600

aaacaacuac uccccauccu aaacaaacag ucaugcagca uauccaacau cgaaaccguc      660

auggaguucc aacagaaaaa caaccgccuc cuugaaauca cccgcgaguu cucugucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacaa acuccgaacu ccucagccuc      780

aucaacgaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      840

guucgucaac aaucauacuc aaucaugugc aucauuaaag aagaaguccu cgcauacguc      900

guccaacucc cccucuaugg ggucaucgac accccaugcu ggaaacucca caccucuccc      960

cuaugcacca ccaacaccaa agaaggcucc aacaucugcc uaacccgaac cgaccgcgga     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgaaac auguaaaguc     1080

ugcuccaacc guguguucug cgacaccaug aacucacuaa cccuccccuc cgaagucaac     1140

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaauaaugac cagcaaaaca     1200

gacguauccu cuagcgucau uaccagccua ggugcaaucg uguccugcua cggcaaaaca     1260

aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa ccuucuccaa cggcugcgac     1320

uacgucagca acaaaggagu cgacaccguc uccguaggaa auacucuaua cuaugucaac     1380

aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccucugacga guucgacgcc agcauaucac aaguaaacga aaagaucaac     1500

caaucccucg cauucauucg caaauccgac gaacuccuac acaacgucaa cgccggaaaa     1560

uccaccacca acaucaugau cacuacuauc auuaucguca ucaucgucau ccuccucucc     1620

cucaucgcag ucggccuucu acucuacugc aaggcacgcu cuacacccgu aacccugucu     1680

aaagaccaac ucuccggcau caacaacauc gcuuucucca acuaaggacu aguguccacc     1740

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1800

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1920

ucagagccac cagaauu                                                    1937


<210>  6979
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6979
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6980
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6980
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cuccaccccg gugacccuga gcaaggacca gcuguccggg     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6981
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6981
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6982
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6982
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gucuacaccg gugaccuuga gcaaagacca gcuguccggc     1680

aucaacaaua uagcuuucuc aaacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6983
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6983
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6984
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6984
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cuccacaccu gugacccuga gcaaagacca gcuuucuggg     1680

aucaacaaua uugcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6985
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6985
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacucaaa      120

gcaaaugcaa uuaccacuau acucacagcu guaacuuuuu guuucgccuc aggacaaaac      180

aucacagaag aauuuuauca auccacaugc ucugccguau caaaaggcua ccuaucugcc      240

cuaagaacag guugguacac aucuguaaua acaaucgaau uauccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaaac aagaauuaga uaaauauaaa      360

aacgcaguaa cagaacuaca aaugcuaaug ugcucuacac ccgccacagg aucaggaucc      420

gcaaucgcuu cuggaguagc cguuugcaaa guauuacacc uagaaggaga aguaaauaaa      480

auaaaauccg cacuacuauc aacuaauaaa gcaguaguau cacuuucuaa ugguguauca      540

guauuaacau ucaaaguccu cgaccuaaaa aauuacaucg acaaacaacu auuacccauc      600

cuuaauaaac aaucaugcuc cauaucaaac auagaaacug ucauggaauu ucaacaaaaa      660

aacaauagac uucuagaaau cacaagagaa uuuucuguaa augcaggagu aacuacacca      720

guaucaacau auauguuaac caacuccgaa cuacuaucac ucauaaacga caugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguucaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguu uuagcauacg ucguacaacu uccccuauac      900

ggaguaauag acaccccuug cuggaaacuc cacaccucac cacuaugcac uacaaacaca      960

aaagaagguu ccaacaucug cuuaacaaga accgaucgag gaugguacug cgacaacgcu     1020

gguuccguau cuuucuuccc acaagcagaa acaugcaaag uaugcuccaa uagaguauuc     1080

ugcgacacca ugaacucacu aacucuacca uccgaaguaa accuaugcaa cgucgacaua     1140

uuuaauccaa aauaugacug caaaauaaug acuucaaaaa cagacguauc cucaucagua     1200

auaacauccu uaggagcaau aguaucaugu uacggcaaga caaaauguac agccucaaac     1260

aaaaacaaag guaucauuaa aaccuucucc aacggcugcg acuacguauc aaauaaaggu     1320

gucgauacag uaucaguagg aaacacacuc uauuacguua auaaacaaga aggaaaguca     1380

uuauacguaa aaggagaacc aauaaucaau uucuacgauc cccuagucuu ucccucagau     1440

gaauuugacg caagcaucuc ucaagucaac gaaaaaauaa accaaucccu agccuucaua     1500

agaaaaucag augaacuacu ucauaacguc aacgccggaa aaucaacaac caacauaaug     1560

aucacuacaa ucauaauugu aauuauagua auacuacuau cgcuaauugc cguuggacua     1620

cuacuauauu guaaagcaag aucaacaccc guuacucuau ccaaagauca auuaucagga     1680

aucaacaaca uagccuucuc aaauuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6986
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6986
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuuaaa      120

gccaacgcaa uaaccacaau ccucaccgcc gucacauucu gcuucgccuc gggacaaaac      180

auaaccgaag aauuuuacca gucuaccugc uccgccgucu ccaaggguua ccucuccgcg      240

cuccgcaccg ggugguacac cagcguuauc accaucgaac uaucuaacau aaaagaaaac      300

aagugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaag      360

aaugccguca ccgaacuaca aaugcucaug ugcuccaccc ccgccaccgg auccggcucc      420

gccauugccu ccggcgucgc cguaugcaaa guccuucacu uggaaggaga aguuaacaaa      480

auaaaaagcg cccuccuguc gaccaacaaa gcggugguca gccucuccaa cggcgucucu      540

guccucaccu ucaaaguccu cgaccucaag aacuacauag auaaacaacu acuccccauc      600

cuaaacaaac agucaugcag cauauccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaccgcc uccuugaaau cacccgcgag uucucuguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucguca acaaucauac      840

ucaaucaugu gcaucauuaa agaagaaguc cucgcauacg ucguccaacu cccccucuau      900

ggggucaucg acaccccaug cuggaaacuc cacaccucuc cccuaugcac caccaacacc      960

aaagaaggcu ccaacaucug ccuaacccga accgaccgcg gaugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgaa acauguaaag ucugcuccaa ccguguguuc     1080

ugcgacacca ugaacucacu aacccucccc uccgaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaauaaug accagcaaaa cagacguauc cucuagcguc     1200

auuaccagcc uaggugcaau cguguccugc uacggcaaaa caaaaugcac cgccuccaac     1260

aaaaauaaag gaaucauaaa aaccuucucc aacggcugcg acuacgucag caacaaagga     1320

gucgacaccg ucuccguagg aaauacucua uacuauguca acaaacaaga ggguaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccucugac     1440

gaguucgacg ccagcauauc acaaguaaac gaaaagauca accaaucccu cgcauucauu     1500

cgcaaauccg acgaacuccu acacaacguc aacgccggaa aauccaccac caacaucaug     1560

aucacuacua ucauuaucgu caucaucguc auccuccucu cccucaucgc agucggccuu     1620

cuacucuacu gcaaggcacg cucuacaccc guaacccugu cuaaagacca acucuccggc     1680

aucaacaaca ucgcuuucuc caacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  6987
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6987
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6988
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6988
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cuccaccccg     1620

gugacccuga gcaaggacca gcuguccggg aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6989
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6989
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6990
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6990
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gucuacaccg     1620

gugaccuuga gcaaagacca gcuguccggc aucaacaaua uagcuuucuc aaacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6991
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6991
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6992
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  6992
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cuccacaccu     1620

gugacccuga gcaaagacca gcuuucuggg aucaacaaua uugcguucuc caacugagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6993
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  6993
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacucaaa gcaaaugcaa uuaccacuau acucacagcu      120

guaacuuuuu guuucgccuc aggacaaaac aucacagaag aauuuuauca auccacaugc      180

ucugccguau caaaaggcua ccuaucugcc cuaagaacag guugguacac aucuguaaua      240

acaaucgaau uauccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaaac aagaauuaga uaaauauaaa aacgcaguaa cagaacuaca aaugcuaaug      360

ugcucuacac ccgccacagg aucaggaucc gcaaucgcuu cuggaguagc cguuugcaaa      420

guauuacacc uagaaggaga aguaaauaaa auaaaauccg cacuacuauc aacuaauaaa      480

gcaguaguau cacuuucuaa ugguguauca guauuaacau ucaaaguccu cgaccuaaaa      540

aauuacaucg acaaacaacu auuacccauc cuuaauaaac aaucaugcuc cauaucaaac      600

auagaaacug ucauggaauu ucaacaaaaa aacaauagac uucuagaaau cacaagagaa      660

uuuucuguaa augcaggagu aacuacacca guaucaacau auauguuaac caacuccgaa      720

cuacuaucac ucauaaacga caugccaaua acaaacgacc aaaaaaaacu aaugucaaau      780

aacguucaaa uaguaagaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu uccccuauac ggaguaauag acaccccuug cuggaaacuc      900

cacaccucac cacuaugcac uacaaacaca aaagaagguu ccaacaucug cuuaacaaga      960

accgaucgag gaugguacug cgacaacgcu gguuccguau cuuucuuccc acaagcagaa     1020

acaugcaaag uaugcuccaa uagaguauuc ugcgacacca ugaacucacu aacucuacca     1080

uccgaaguaa accuaugcaa cgucgacaua uuuaauccaa aauaugacug caaaauaaug     1140

acuucaaaaa cagacguauc cucaucagua auaacauccu uaggagcaau aguaucaugu     1200

uacggcaaga caaaauguac agccucaaac aaaaacaaag guaucauuaa aaccuucucc     1260

aacggcugcg acuacguauc aaauaaaggu gucgauacag uaucaguagg aaacacacuc     1320

uauuacguua auaaacaaga aggaaaguca uuauacguaa aaggagaacc aauaaucaau     1380

uucuacgauc cccuagucuu ucccucagau gaauuugacg caagcaucuc ucaagucaac     1440

gaaaaaauaa accaaucccu agccuucaua agaaaaucag augaacuacu ucauaacguc     1500

aacgccggaa aaucaacaac caacauaaug aucacuacaa ucauaauugu aauuauagua     1560

auacuacuau cgcuaauugc cguuggacua cuacuauauu guaaagcaag aucaacaccc     1620

guuacucuau ccaaagauca auuaucagga aucaacaaca uagccuucuc aaauuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6994
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  6994
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuuaaa gccaacgcaa uaaccacaau ccucaccgcc      120

gucacauucu gcuucgccuc gggacaaaac auaaccgaag aauuuuacca gucuaccugc      180

uccgccgucu ccaaggguua ccucuccgcg cuccgcaccg ggugguacac cagcguuauc      240

accaucgaac uaucuaacau aaaagaaaac aagugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaag aaugccguca ccgaacuaca aaugcucaug      360

ugcuccaccc ccgccaccgg auccggcucc gccauugccu ccggcgucgc cguaugcaaa      420

guccuucacu uggaaggaga aguuaacaaa auaaaaagcg cccuccuguc gaccaacaaa      480

gcggugguca gccucuccaa cggcgucucu guccucaccu ucaaaguccu cgaccucaag      540

aacuacauag auaaacaacu acuccccauc cuaaacaaac agucaugcag cauauccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaccgcc uccuugaaau cacccgcgag      660

uucucuguca acgccggcgu caccaccccc gucuccaccu acaugcucac aaacuccgaa      720

cuccucagcc ucaucaacga caugccaauc accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucguca acaaucauac ucaaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg ucguccaacu cccccucuau ggggucaucg acaccccaug cuggaaacuc      900

cacaccucuc cccuaugcac caccaacacc aaagaaggcu ccaacaucug ccuaacccga      960

accgaccgcg gaugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgaa     1020

acauguaaag ucugcuccaa ccguguguuc ugcgacacca ugaacucacu aacccucccc     1080

uccgaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaauaaug     1140

accagcaaaa cagacguauc cucuagcguc auuaccagcc uaggugcaau cguguccugc     1200

uacggcaaaa caaaaugcac cgccuccaac aaaaauaaag gaaucauaaa aaccuucucc     1260

aacggcugcg acuacgucag caacaaagga gucgacaccg ucuccguagg aaauacucua     1320

uacuauguca acaaacaaga ggguaaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccucugac gaguucgacg ccagcauauc acaaguaaac     1440

gaaaagauca accaaucccu cgcauucauu cgcaaauccg acgaacuccu acacaacguc     1500

aacgccggaa aauccaccac caacaucaug aucacuacua ucauuaucgu caucaucguc     1560

auccuccucu cccucaucgc agucggccuu cuacucuacu gcaaggcacg cucuacaccc     1620

guaacccugu cuaaagacca acucuccggc aucaacaaca ucgcuuucuc caacuaagga     1680

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1740

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  6995
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6995
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6996
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  6996
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcuccac cccggugacc     1680

cugagcaagg accagcuguc cgggaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6997
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  6997
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6998
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  6998
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggucuac accggugacc     1680

uugagcaaag accagcuguc cggcaucaac aauauagcuu ucucaaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  6999
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  6999
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7000
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7000
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcuccac accugugacc     1680

cugagcaaag accagcuuuc ugggaucaac aauauugcgu ucuccaacug aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7001
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7001
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu caaagcaaau gcaauuacca cuauacucac agcuguaacu      180

uuuuguuucg ccucaggaca aaacaucaca gaagaauuuu aucaauccac augcucugcc      240

guaucaaaag gcuaccuauc ugcccuaaga acagguuggu acacaucugu aauaacaauc      300

gaauuaucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aaacaagaau uagauaaaua uaaaaacgca guaacagaac uacaaaugcu aaugugcucu      420

acacccgcca caggaucagg auccgcaauc gcuucuggag uagccguuug caaaguauua      480

caccuagaag gagaaguaaa uaaaauaaaa uccgcacuac uaucaacuaa uaaagcagua      540

guaucacuuu cuaauggugu aucaguauua acauucaaag uccucgaccu aaaaaauuac      600

aucgacaaac aacuauuacc cauccuuaau aaacaaucau gcuccauauc aaacauagaa      660

acugucaugg aauuucaaca aaaaaacaau agacuucuag aaaucacaag agaauuuucu      720

guaaaugcag gaguaacuac accaguauca acauauaugu uaaccaacuc cgaacuacua      780

ucacucauaa acgacaugcc aauaacaaac gaccaaaaaa aacuaauguc aaauaacguu      840

caaauaguaa gacaacaauc auacucaauc augugcauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuuccccu auacggagua auagacaccc cuugcuggaa acuccacacc      960

ucaccacuau gcacuacaaa cacaaaagaa gguuccaaca ucugcuuaac aagaaccgau     1020

cgaggauggu acugcgacaa cgcugguucc guaucuuucu ucccacaagc agaaacaugc     1080

aaaguaugcu ccaauagagu auucugcgac accaugaacu cacuaacucu accauccgaa     1140

guaaaccuau gcaacgucga cauauuuaau ccaaaauaug acugcaaaau aaugacuuca     1200

aaaacagacg uauccucauc aguaauaaca uccuuaggag caauaguauc auguuacggc     1260

aagacaaaau guacagccuc aaacaaaaac aaagguauca uuaaaaccuu cuccaacggc     1320

ugcgacuacg uaucaaauaa aggugucgau acaguaucag uaggaaacac acucuauuac     1380

guuaauaaac aagaaggaaa gucauuauac guaaaaggag aaccaauaau caauuucuac     1440

gauccccuag ucuuucccuc agaugaauuu gacgcaagca ucucucaagu caacgaaaaa     1500

auaaaccaau cccuagccuu cauaagaaaa ucagaugaac uacuucauaa cgucaacgcc     1560

ggaaaaucaa caaccaacau aaugaucacu acaaucauaa uuguaauuau aguaauacua     1620

cuaucgcuaa uugccguugg acuacuacua uauuguaaag caagaucaac acccguuacu     1680

cuauccaaag aucaauuauc aggaaucaac aacauagccu ucucaaauua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7002
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7002
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu uaaagccaac gcaauaacca caauccucac cgccgucaca      180

uucugcuucg ccucgggaca aaacauaacc gaagaauuuu accagucuac cugcuccgcc      240

gucuccaagg guuaccucuc cgcgcuccgc accggguggu acaccagcgu uaucaccauc      300

gaacuaucua acauaaaaga aaacaagugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caagaaugcc gucaccgaac uacaaaugcu caugugcucc      420

acccccgcca ccggauccgg cuccgccauu gccuccggcg ucgccguaug caaaguccuu      480

cacuuggaag gagaaguuaa caaaauaaaa agcgcccucc ugucgaccaa caaagcggug      540

gucagccucu ccaacggcgu cucuguccuc accuucaaag uccucgaccu caagaacuac      600

auagauaaac aacuacuccc cauccuaaac aaacagucau gcagcauauc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaac cgccuccuug aaaucacccg cgaguucucu      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucacaaacuc cgaacuccuc      780

agccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gucaacaauc auacucaauc augugcauca uuaaagaaga aguccucgca      900

uacgucgucc aacucccccu cuaugggguc aucgacaccc caugcuggaa acuccacacc      960

ucuccccuau gcaccaccaa caccaaagaa ggcuccaaca ucugccuaac ccgaaccgac     1020

cgcggauggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgaaacaugu     1080

aaagucugcu ccaaccgugu guucugcgac accaugaacu cacuaacccu ccccuccgaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau aaugaccagc     1200

aaaacagacg uauccucuag cgucauuacc agccuaggug caaucguguc cugcuacggc     1260

aaaacaaaau gcaccgccuc caacaaaaau aaaggaauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg ucagcaacaa aggagucgac accgucuccg uaggaaauac ucuauacuau     1380

gucaacaaac aagaggguaa aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc ugacgaguuc gacgccagca uaucacaagu aaacgaaaag     1500

aucaaccaau cccucgcauu cauucgcaaa uccgacgaac uccuacacaa cgucaacgcc     1560

ggaaaaucca ccaccaacau caugaucacu acuaucauua ucgucaucau cgucauccuc     1620

cucucccuca ucgcagucgg ccuucuacuc uacugcaagg cacgcucuac acccguaacc     1680

cugucuaaag accaacucuc cggcaucaac aacaucgcuu ucuccaacua aggacuagug     1740

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1800

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7003
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7003
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7004
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7004
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcuccacccc ggugacccug agcaaggacc agcuguccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7005
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7005
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7006
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7006
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggucuacacc ggugaccuug agcaaagacc agcuguccgg caucaacaau     1680

auagcuuucu caaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7007
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7007
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7008
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7008
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcuccacacc ugugacccug agcaaagacc agcuuucugg gaucaacaau     1680

auugcguucu ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7009
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7009
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacucaa agcaaaugca      120

auuaccacua uacucacagc uguaacuuuu uguuucgccu caggacaaaa caucacagaa      180

gaauuuuauc aauccacaug cucugccgua ucaaaaggcu accuaucugc ccuaagaaca      240

gguugguaca caucuguaau aacaaucgaa uuauccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaaa caagaauuag auaaauauaa aaacgcagua      360

acagaacuac aaaugcuaau gugcucuaca cccgccacag gaucaggauc cgcaaucgcu      420

ucuggaguag ccguuugcaa aguauuacac cuagaaggag aaguaaauaa aauaaaaucc      480

gcacuacuau caacuaauaa agcaguagua ucacuuucua augguguauc aguauuaaca      540

uucaaagucc ucgaccuaaa aaauuacauc gacaaacaac uauuacccau ccuuaauaaa      600

caaucaugcu ccauaucaaa cauagaaacu gucauggaau uucaacaaaa aaacaauaga      660

cuucuagaaa ucacaagaga auuuucugua aaugcaggag uaacuacacc aguaucaaca      720

uauauguuaa ccaacuccga acuacuauca cucauaaacg acaugccaau aacaaacgac      780

caaaaaaaac uaaugucaaa uaacguucaa auaguaagac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu uuuagcauac gucguacaac uuccccuaua cggaguaaua      900

gacaccccuu gcuggaaacu ccacaccuca ccacuaugca cuacaaacac aaaagaaggu      960

uccaacaucu gcuuaacaag aaccgaucga ggaugguacu gcgacaacgc ugguuccgua     1020

ucuuucuucc cacaagcaga aacaugcaaa guaugcucca auagaguauu cugcgacacc     1080

augaacucac uaacucuacc auccgaagua aaccuaugca acgucgacau auuuaaucca     1140

aaauaugacu gcaaaauaau gacuucaaaa acagacguau ccucaucagu aauaacaucc     1200

uuaggagcaa uaguaucaug uuacggcaag acaaaaugua cagccucaaa caaaaacaaa     1260

gguaucauua aaaccuucuc caacggcugc gacuacguau caaauaaagg ugucgauaca     1320

guaucaguag gaaacacacu cuauuacguu aauaaacaag aaggaaaguc auuauacgua     1380

aaaggagaac caauaaucaa uuucuacgau ccccuagucu uucccucaga ugaauuugac     1440

gcaagcaucu cucaagucaa cgaaaaaaua aaccaauccc uagccuucau aagaaaauca     1500

gaugaacuac uucauaacgu caacgccgga aaaucaacaa ccaacauaau gaucacuaca     1560

aucauaauug uaauuauagu aauacuacua ucgcuaauug ccguuggacu acuacuauau     1620

uguaaagcaa gaucaacacc cguuacucua uccaaagauc aauuaucagg aaucaacaac     1680

auagccuucu caaauuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7010
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7010
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuuaa agccaacgca      120

auaaccacaa uccucaccgc cgucacauuc ugcuucgccu cgggacaaaa cauaaccgaa      180

gaauuuuacc agucuaccug cuccgccguc uccaaggguu accucuccgc gcuccgcacc      240

gggugguaca ccagcguuau caccaucgaa cuaucuaaca uaaaagaaaa caagugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa gaaugccguc      360

accgaacuac aaaugcucau gugcuccacc cccgccaccg gauccggcuc cgccauugcc      420

uccggcgucg ccguaugcaa aguccuucac uuggaaggag aaguuaacaa aauaaaaagc      480

gcccuccugu cgaccaacaa agcggugguc agccucucca acggcgucuc uguccucacc      540

uucaaagucc ucgaccucaa gaacuacaua gauaaacaac uacuccccau ccuaaacaaa      600

cagucaugca gcauauccaa caucgaaacc gucauggagu uccaacagaa aaacaaccgc      660

cuccuugaaa ucacccgcga guucucuguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca caaacuccga acuccucagc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucguc aacaaucaua cucaaucaug      840

ugcaucauua aagaagaagu ccucgcauac gucguccaac ucccccucua uggggucauc      900

gacaccccau gcuggaaacu ccacaccucu ccccuaugca ccaccaacac caaagaaggc      960

uccaacaucu gccuaacccg aaccgaccgc ggaugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga aacauguaaa gucugcucca accguguguu cugcgacacc     1080

augaacucac uaacccuccc cuccgaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaauaau gaccagcaaa acagacguau ccucuagcgu cauuaccagc     1200

cuaggugcaa ucguguccug cuacggcaaa acaaaaugca ccgccuccaa caaaaauaaa     1260

ggaaucauaa aaaccuucuc caacggcugc gacuacguca gcaacaaagg agucgacacc     1320

gucuccguag gaaauacucu auacuauguc aacaaacaag aggguaaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccucuga cgaguucgac     1440

gccagcauau cacaaguaaa cgaaaagauc aaccaauccc ucgcauucau ucgcaaaucc     1500

gacgaacucc uacacaacgu caacgccgga aaauccacca ccaacaucau gaucacuacu     1560

aucauuaucg ucaucaucgu cauccuccuc ucccucaucg cagucggccu ucuacucuac     1620

ugcaaggcac gcucuacacc cguaacccug ucuaaagacc aacucuccgg caucaacaac     1680

aucgcuuucu ccaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu     1740

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7011
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7011
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7012
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7012
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcuccacccc ggugacccug agcaaggacc agcuguccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7013
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7013
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7014
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7014
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggucuacacc ggugaccuug agcaaagacc agcuguccgg caucaacaau     1680

auagcuuucu caaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7015
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7015
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7016
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7016
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcuccacacc ugugacccug agcaaagacc agcuuucugg gaucaacaau     1680

auugcguucu ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7017
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7017
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacucaa agcaaaugca      120

auuaccacua uacucacagc uguaacuuuu uguuucgccu caggacaaaa caucacagaa      180

gaauuuuauc aauccacaug cucugccgua ucaaaaggcu accuaucugc ccuaagaaca      240

gguugguaca caucuguaau aacaaucgaa uuauccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaaa caagaauuag auaaauauaa aaacgcagua      360

acagaacuac aaaugcuaau gugcucuaca cccgccacag gaucaggauc cgcaaucgcu      420

ucuggaguag ccguuugcaa aguauuacac cuagaaggag aaguaaauaa aauaaaaucc      480

gcacuacuau caacuaauaa agcaguagua ucacuuucua augguguauc aguauuaaca      540

uucaaagucc ucgaccuaaa aaauuacauc gacaaacaac uauuacccau ccuuaauaaa      600

caaucaugcu ccauaucaaa cauagaaacu gucauggaau uucaacaaaa aaacaauaga      660

cuucuagaaa ucacaagaga auuuucugua aaugcaggag uaacuacacc aguaucaaca      720

uauauguuaa ccaacuccga acuacuauca cucauaaacg acaugccaau aacaaacgac      780

caaaaaaaac uaaugucaaa uaacguucaa auaguaagac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu uuuagcauac gucguacaac uuccccuaua cggaguaaua      900

gacaccccuu gcuggaaacu ccacaccuca ccacuaugca cuacaaacac aaaagaaggu      960

uccaacaucu gcuuaacaag aaccgaucga ggaugguacu gcgacaacgc ugguuccgua     1020

ucuuucuucc cacaagcaga aacaugcaaa guaugcucca auagaguauu cugcgacacc     1080

augaacucac uaacucuacc auccgaagua aaccuaugca acgucgacau auuuaaucca     1140

aaauaugacu gcaaaauaau gacuucaaaa acagacguau ccucaucagu aauaacaucc     1200

uuaggagcaa uaguaucaug uuacggcaag acaaaaugua cagccucaaa caaaaacaaa     1260

gguaucauua aaaccuucuc caacggcugc gacuacguau caaauaaagg ugucgauaca     1320

guaucaguag gaaacacacu cuauuacguu aauaaacaag aaggaaaguc auuauacgua     1380

aaaggagaac caauaaucaa uuucuacgau ccccuagucu uucccucaga ugaauuugac     1440

gcaagcaucu cucaagucaa cgaaaaaaua aaccaauccc uagccuucau aagaaaauca     1500

gaugaacuac uucauaacgu caacgccgga aaaucaacaa ccaacauaau gaucacuaca     1560

aucauaauug uaauuauagu aauacuacua ucgcuaauug ccguuggacu acuacuauau     1620

uguaaagcaa gaucaacacc cguuacucua uccaaagauc aauuaucagg aaucaacaac     1680

auagccuucu caaauuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7018
<211>  1977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7018
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuuaa agccaacgca      120

auaaccacaa uccucaccgc cgucacauuc ugcuucgccu cgggacaaaa cauaaccgaa      180

gaauuuuacc agucuaccug cuccgccguc uccaaggguu accucuccgc gcuccgcacc      240

gggugguaca ccagcguuau caccaucgaa cuaucuaaca uaaaagaaaa caagugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa gaaugccguc      360

accgaacuac aaaugcucau gugcuccacc cccgccaccg gauccggcuc cgccauugcc      420

uccggcgucg ccguaugcaa aguccuucac uuggaaggag aaguuaacaa aauaaaaagc      480

gcccuccugu cgaccaacaa agcggugguc agccucucca acggcgucuc uguccucacc      540

uucaaagucc ucgaccucaa gaacuacaua gauaaacaac uacuccccau ccuaaacaaa      600

cagucaugca gcauauccaa caucgaaacc gucauggagu uccaacagaa aaacaaccgc      660

cuccuugaaa ucacccgcga guucucuguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca caaacuccga acuccucagc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucguc aacaaucaua cucaaucaug      840

ugcaucauua aagaagaagu ccucgcauac gucguccaac ucccccucua uggggucauc      900

gacaccccau gcuggaaacu ccacaccucu ccccuaugca ccaccaacac caaagaaggc      960

uccaacaucu gccuaacccg aaccgaccgc ggaugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga aacauguaaa gucugcucca accguguguu cugcgacacc     1080

augaacucac uaacccuccc cuccgaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaauaau gaccagcaaa acagacguau ccucuagcgu cauuaccagc     1200

cuaggugcaa ucguguccug cuacggcaaa acaaaaugca ccgccuccaa caaaaauaaa     1260

ggaaucauaa aaaccuucuc caacggcugc gacuacguca gcaacaaagg agucgacacc     1320

gucuccguag gaaauacucu auacuauguc aacaaacaag aggguaaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccucuga cgaguucgac     1440

gccagcauau cacaaguaaa cgaaaagauc aaccaauccc ucgcauucau ucgcaaaucc     1500

gacgaacucc uacacaacgu caacgccgga aaauccacca ccaacaucau gaucacuacu     1560

aucauuaucg ucaucaucgu cauccuccuc ucccucaucg cagucggccu ucuacucuac     1620

ugcaaggcac gcucuacacc cguaacccug ucuaaagacc aacucuccgg caucaacaac     1680

aucgcuuucu ccaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1740

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1800

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1920

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1977


<210>  7019
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7019
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7020
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7020
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcuccacccc ggugacccug agcaaggacc agcuguccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7021
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7021
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7022
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7022
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggucuacacc ggugaccuug agcaaagacc agcuguccgg caucaacaau     1680

auagcuuucu caaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7023
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7023
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7024
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7024
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcuccacacc ugugacccug agcaaagacc agcuuucugg gaucaacaau     1680

auugcguucu ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7025
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7025
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacucaa agcaaaugca      120

auuaccacua uacucacagc uguaacuuuu uguuucgccu caggacaaaa caucacagaa      180

gaauuuuauc aauccacaug cucugccgua ucaaaaggcu accuaucugc ccuaagaaca      240

gguugguaca caucuguaau aacaaucgaa uuauccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaaa caagaauuag auaaauauaa aaacgcagua      360

acagaacuac aaaugcuaau gugcucuaca cccgccacag gaucaggauc cgcaaucgcu      420

ucuggaguag ccguuugcaa aguauuacac cuagaaggag aaguaaauaa aauaaaaucc      480

gcacuacuau caacuaauaa agcaguagua ucacuuucua augguguauc aguauuaaca      540

uucaaagucc ucgaccuaaa aaauuacauc gacaaacaac uauuacccau ccuuaauaaa      600

caaucaugcu ccauaucaaa cauagaaacu gucauggaau uucaacaaaa aaacaauaga      660

cuucuagaaa ucacaagaga auuuucugua aaugcaggag uaacuacacc aguaucaaca      720

uauauguuaa ccaacuccga acuacuauca cucauaaacg acaugccaau aacaaacgac      780

caaaaaaaac uaaugucaaa uaacguucaa auaguaagac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu uuuagcauac gucguacaac uuccccuaua cggaguaaua      900

gacaccccuu gcuggaaacu ccacaccuca ccacuaugca cuacaaacac aaaagaaggu      960

uccaacaucu gcuuaacaag aaccgaucga ggaugguacu gcgacaacgc ugguuccgua     1020

ucuuucuucc cacaagcaga aacaugcaaa guaugcucca auagaguauu cugcgacacc     1080

augaacucac uaacucuacc auccgaagua aaccuaugca acgucgacau auuuaaucca     1140

aaauaugacu gcaaaauaau gacuucaaaa acagacguau ccucaucagu aauaacaucc     1200

uuaggagcaa uaguaucaug uuacggcaag acaaaaugua cagccucaaa caaaaacaaa     1260

gguaucauua aaaccuucuc caacggcugc gacuacguau caaauaaagg ugucgauaca     1320

guaucaguag gaaacacacu cuauuacguu aauaaacaag aaggaaaguc auuauacgua     1380

aaaggagaac caauaaucaa uuucuacgau ccccuagucu uucccucaga ugaauuugac     1440

gcaagcaucu cucaagucaa cgaaaaaaua aaccaauccc uagccuucau aagaaaauca     1500

gaugaacuac uucauaacgu caacgccgga aaaucaacaa ccaacauaau gaucacuaca     1560

aucauaauug uaauuauagu aauacuacua ucgcuaauug ccguuggacu acuacuauau     1620

uguaaagcaa gaucaacacc cguuacucua uccaaagauc aauuaucagg aaucaacaac     1680

auagccuucu caaauuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7026
<211>  2193
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7026
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuuaa agccaacgca      120

auaaccacaa uccucaccgc cgucacauuc ugcuucgccu cgggacaaaa cauaaccgaa      180

gaauuuuacc agucuaccug cuccgccguc uccaaggguu accucuccgc gcuccgcacc      240

gggugguaca ccagcguuau caccaucgaa cuaucuaaca uaaaagaaaa caagugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa gaaugccguc      360

accgaacuac aaaugcucau gugcuccacc cccgccaccg gauccggcuc cgccauugcc      420

uccggcgucg ccguaugcaa aguccuucac uuggaaggag aaguuaacaa aauaaaaagc      480

gcccuccugu cgaccaacaa agcggugguc agccucucca acggcgucuc uguccucacc      540

uucaaagucc ucgaccucaa gaacuacaua gauaaacaac uacuccccau ccuaaacaaa      600

cagucaugca gcauauccaa caucgaaacc gucauggagu uccaacagaa aaacaaccgc      660

cuccuugaaa ucacccgcga guucucuguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca caaacuccga acuccucagc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucguc aacaaucaua cucaaucaug      840

ugcaucauua aagaagaagu ccucgcauac gucguccaac ucccccucua uggggucauc      900

gacaccccau gcuggaaacu ccacaccucu ccccuaugca ccaccaacac caaagaaggc      960

uccaacaucu gccuaacccg aaccgaccgc ggaugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga aacauguaaa gucugcucca accguguguu cugcgacacc     1080

augaacucac uaacccuccc cuccgaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaauaau gaccagcaaa acagacguau ccucuagcgu cauuaccagc     1200

cuaggugcaa ucguguccug cuacggcaaa acaaaaugca ccgccuccaa caaaaauaaa     1260

ggaaucauaa aaaccuucuc caacggcugc gacuacguca gcaacaaagg agucgacacc     1320

gucuccguag gaaauacucu auacuauguc aacaaacaag aggguaaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccucuga cgaguucgac     1440

gccagcauau cacaaguaaa cgaaaagauc aaccaauccc ucgcauucau ucgcaaaucc     1500

gacgaacucc uacacaacgu caacgccgga aaauccacca ccaacaucau gaucacuacu     1560

aucauuaucg ucaucaucgu cauccuccuc ucccucaucg cagucggccu ucuacucuac     1620

ugcaaggcac gcucuacacc cguaacccug ucuaaagacc aacucuccgg caucaacaac     1680

aucgcuuucu ccaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1740

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1800

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1860

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1920

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1980

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     2040

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2160

cccccaaagg cucuuuucag agccaccaga auu                                  2193


<210>  7027
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7027
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac     1680

aucgcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7028
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7028
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcuccacccc ggugacccug agcaaggacc agcuguccgg gaucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7029
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7029
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac     1680

aucgccuucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7030
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7030
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggucuacacc ggugaccuug agcaaagacc agcuguccgg caucaacaau     1680

auagcuuucu caaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7031
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7031
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac     1680

aucgccuuca gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7032
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7032
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcuccacacc ugugacccug agcaaagacc agcuuucugg gaucaacaau     1680

auugcguucu ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7033
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7033
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac ucauacucaa agcaaaugca      120

auuaccacua uacucacagc uguaacuuuu uguuucgccu caggacaaaa caucacagaa      180

gaauuuuauc aauccacaug cucugccgua ucaaaaggcu accuaucugc ccuaagaaca      240

gguugguaca caucuguaau aacaaucgaa uuauccaaca ucaaagaaaa caaaugcaac      300

ggcacagacg caaaagucaa acucaucaaa caagaauuag auaaauauaa aaacgcagua      360

acagaacuac aaaugcuaau gugcucuaca cccgccacag gaucaggauc cgcaaucgcu      420

ucuggaguag ccguuugcaa aguauuacac cuagaaggag aaguaaauaa aauaaaaucc      480

gcacuacuau caacuaauaa agcaguagua ucacuuucua augguguauc aguauuaaca      540

uucaaagucc ucgaccuaaa aaauuacauc gacaaacaac uauuacccau ccuuaauaaa      600

caaucaugcu ccauaucaaa cauagaaacu gucauggaau uucaacaaaa aaacaauaga      660

cuucuagaaa ucacaagaga auuuucugua aaugcaggag uaacuacacc aguaucaaca      720

uauauguuaa ccaacuccga acuacuauca cucauaaacg acaugccaau aacaaacgac      780

caaaaaaaac uaaugucaaa uaacguucaa auaguaagac aacaaucaua cucaaucaug      840

ugcauaauaa aagaagaagu uuuagcauac gucguacaac uuccccuaua cggaguaaua      900

gacaccccuu gcuggaaacu ccacaccuca ccacuaugca cuacaaacac aaaagaaggu      960

uccaacaucu gcuuaacaag aaccgaucga ggaugguacu gcgacaacgc ugguuccgua     1020

ucuuucuucc cacaagcaga aacaugcaaa guaugcucca auagaguauu cugcgacacc     1080

augaacucac uaacucuacc auccgaagua aaccuaugca acgucgacau auuuaaucca     1140

aaauaugacu gcaaaauaau gacuucaaaa acagacguau ccucaucagu aauaacaucc     1200

uuaggagcaa uaguaucaug uuacggcaag acaaaaugua cagccucaaa caaaaacaaa     1260

gguaucauua aaaccuucuc caacggcugc gacuacguau caaauaaagg ugucgauaca     1320

guaucaguag gaaacacacu cuauuacguu aauaaacaag aaggaaaguc auuauacgua     1380

aaaggagaac caauaaucaa uuucuacgau ccccuagucu uucccucaga ugaauuugac     1440

gcaagcaucu cucaagucaa cgaaaaaaua aaccaauccc uagccuucau aagaaaauca     1500

gaugaacuac uucauaacgu caacgccgga aaaucaacaa ccaacauaau gaucacuaca     1560

aucauaauug uaauuauagu aauacuacua ucgcuaauug ccguuggacu acuacuauau     1620

uguaaagcaa gaucaacacc cguuacucua uccaaagauc aauuaucagg aaucaacaac     1680

auagccuucu caaauuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7034
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7034
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauacuuaa agccaacgca      120

auaaccacaa uccucaccgc cgucacauuc ugcuucgccu cgggacaaaa cauaaccgaa      180

gaauuuuacc agucuaccug cuccgccguc uccaaggguu accucuccgc gcuccgcacc      240

gggugguaca ccagcguuau caccaucgaa cuaucuaaca uaaaagaaaa caagugcaac      300

ggaaccgacg caaaagucaa acucaucaaa caagaacuag acaaauacaa gaaugccguc      360

accgaacuac aaaugcucau gugcuccacc cccgccaccg gauccggcuc cgccauugcc      420

uccggcgucg ccguaugcaa aguccuucac uuggaaggag aaguuaacaa aauaaaaagc      480

gcccuccugu cgaccaacaa agcggugguc agccucucca acggcgucuc uguccucacc      540

uucaaagucc ucgaccucaa gaacuacaua gauaaacaac uacuccccau ccuaaacaaa      600

cagucaugca gcauauccaa caucgaaacc gucauggagu uccaacagaa aaacaaccgc      660

cuccuugaaa ucacccgcga guucucuguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca caaacuccga acuccucagc cucaucaacg acaugccaau caccaacgac      780

caaaagaaac ucauguccaa caacguacaa aucguucguc aacaaucaua cucaaucaug      840

ugcaucauua aagaagaagu ccucgcauac gucguccaac ucccccucua uggggucauc      900

gacaccccau gcuggaaacu ccacaccucu ccccuaugca ccaccaacac caaagaaggc      960

uccaacaucu gccuaacccg aaccgaccgc ggaugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga aacauguaaa gucugcucca accguguguu cugcgacacc     1080

augaacucac uaacccuccc cuccgaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaauaau gaccagcaaa acagacguau ccucuagcgu cauuaccagc     1200

cuaggugcaa ucguguccug cuacggcaaa acaaaaugca ccgccuccaa caaaaauaaa     1260

ggaaucauaa aaaccuucuc caacggcugc gacuacguca gcaacaaagg agucgacacc     1320

gucuccguag gaaauacucu auacuauguc aacaaacaag aggguaaauc ccucuacguc     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccucuga cgaguucgac     1440

gccagcauau cacaaguaaa cgaaaagauc aaccaauccc ucgcauucau ucgcaaaucc     1500

gacgaacucc uacacaacgu caacgccgga aaauccacca ccaacaucau gaucacuacu     1560

aucauuaucg ucaucaucgu cauccuccuc ucccucaucg cagucggccu ucuacucuac     1620

ugcaaggcac gcucuacacc cguaacccug ucuaaagacc aacucuccgg caucaacaac     1680

aucgcuuucu ccaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1740

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1800

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7035
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7035
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7036
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7036
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

ccaccccggu gacccugagc aaggaccagc uguccgggau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7037
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7037
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7038
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7038
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

cuacaccggu gaccuugagc aaagaccagc uguccggcau caacaauaua gcuuucucaa     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7039
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7039
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7040
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7040
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

ccacaccugu gacccugagc aaagaccagc uuucugggau caacaauauu gcguucucca     1680

acugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7041
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7041
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacucaaagc aaaugcaauu accacuauac      120

ucacagcugu aacuuuuugu uucgccucag gacaaaacau cacagaagaa uuuuaucaau      180

ccacaugcuc ugccguauca aaaggcuacc uaucugcccu aagaacaggu ugguacacau      240

cuguaauaac aaucgaauua uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaaacaa gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa      360

ugcuaaugug cucuacaccc gccacaggau caggauccgc aaucgcuucu ggaguagccg      420

uuugcaaagu auuacaccua gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa      480

cuaauaaagc aguaguauca cuuucuaaug guguaucagu auuaacauuc aaaguccucg      540

accuaaaaaa uuacaucgac aaacaacuau uacccauccu uaauaaacaa ucaugcucca      600

uaucaaacau agaaacuguc auggaauuuc aacaaaaaaa caauagacuu cuagaaauca      660

caagagaauu uucuguaaau gcaggaguaa cuacaccagu aucaacauau auguuaacca      720

acuccgaacu acuaucacuc auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa      780

ugucaaauaa cguucaaaua guaagacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguuuu agcauacguc guacaacuuc cccuauacgg aguaauagac accccuugcu      900

ggaaacucca caccucacca cuaugcacua caaacacaaa agaagguucc aacaucugcu      960

uaacaagaac cgaucgagga ugguacugcg acaacgcugg uuccguaucu uucuucccac     1020

aagcagaaac augcaaagua ugcuccaaua gaguauucug cgacaccaug aacucacuaa     1080

cucuaccauc cgaaguaaac cuaugcaacg ucgacauauu uaauccaaaa uaugacugca     1140

aaauaaugac uucaaaaaca gacguauccu caucaguaau aacauccuua ggagcaauag     1200

uaucauguua cggcaagaca aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa     1260

ccuucuccaa cggcugcgac uacguaucaa auaaaggugu cgauacagua ucaguaggaa     1320

acacacucua uuacguuaau aaacaagaag gaaagucauu auacguaaaa ggagaaccaa     1380

uaaucaauuu cuacgauccc cuagucuuuc ccucagauga auuugacgca agcaucucuc     1440

aagucaacga aaaaauaaac caaucccuag ccuucauaag aaaaucagau gaacuacuuc     1500

auaacgucaa cgccggaaaa ucaacaacca acauaaugau cacuacaauc auaauuguaa     1560

uuauaguaau acuacuaucg cuaauugccg uuggacuacu acuauauugu aaagcaagau     1620

caacacccgu uacucuaucc aaagaucaau uaucaggaau caacaacaua gccuucucaa     1680

auuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7042
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7042
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuuaaagc caacgcaaua accacaaucc      120

ucaccgccgu cacauucugc uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu      180

cuaccugcuc cgccgucucc aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca      240

gcguuaucac caucgaacua ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaagaa ugccgucacc gaacuacaaa      360

ugcucaugug cuccaccccc gccaccggau ccggcuccgc cauugccucc ggcgucgccg      420

uaugcaaagu ccuucacuug gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga      480

ccaacaaagc gguggucagc cucuccaacg gcgucucugu ccucaccuuc aaaguccucg      540

accucaagaa cuacauagau aaacaacuac uccccauccu aaacaaacag ucaugcagca      600

uauccaacau cgaaaccguc auggaguucc aacagaaaaa caaccgccuc cuugaaauca      660

cccgcgaguu cucugucaac gccggcguca ccacccccgu cuccaccuac augcucacaa      720

acuccgaacu ccucagccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgucaac aaucauacuc aaucaugugc aucauuaaag      840

aagaaguccu cgcauacguc guccaacucc cccucuaugg ggucaucgac accccaugcu      900

ggaaacucca caccucuccc cuaugcacca ccaacaccaa agaaggcucc aacaucugcc      960

uaacccgaac cgaccgcgga ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgaaac auguaaaguc ugcuccaacc guguguucug cgacaccaug aacucacuaa     1080

cccuccccuc cgaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaauaaugac cagcaaaaca gacguauccu cuagcgucau uaccagccua ggugcaaucg     1200

uguccugcua cggcaaaaca aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa     1260

ccuucuccaa cggcugcgac uacgucagca acaaaggagu cgacaccguc uccguaggaa     1320

auacucuaua cuaugucaac aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccucugacga guucgacgcc agcauaucac     1440

aaguaaacga aaagaucaac caaucccucg cauucauucg caaauccgac gaacuccuac     1500

acaacgucaa cgccggaaaa uccaccacca acaucaugau cacuacuauc auuaucguca     1560

ucaucgucau ccuccucucc cucaucgcag ucggccuucu acucuacugc aaggcacgcu     1620

cuacacccgu aacccugucu aaagaccaac ucuccggcau caacaacauc gcuuucucca     1680

acuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1740

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1800

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7043
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7043
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccgga     1620

gcacgcccgu cacccugucc aaggaccagc ugagcggcau caacaacauc gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7044
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7044
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

ccaccccggu gacccugagc aaggaccagc uguccgggau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7045
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7045
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

ccacccccgu cacccucucc aaggaccagc ucuccggcau caacaacauc gccuucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7046
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7046
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

cuacaccggu gaccuugagc aaagaccagc uguccggcau caacaauaua gcuuucucaa     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7047
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7047
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagaa     1620

gcacccccgu gacccugagc aaggaccagc ugagcggcau caacaacauc gccuucagca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7048
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7048
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

ccacaccugu gacccugagc aaagaccagc uuucugggau caacaauauu gcguucucca     1680

acugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7049
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7049
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuca uacucaaagc aaaugcaauu accacuauac      120

ucacagcugu aacuuuuugu uucgccucag gacaaaacau cacagaagaa uuuuaucaau      180

ccacaugcuc ugccguauca aaaggcuacc uaucugcccu aagaacaggu ugguacacau      240

cuguaauaac aaucgaauua uccaacauca aagaaaacaa augcaacggc acagacgcaa      300

aagucaaacu caucaaacaa gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa      360

ugcuaaugug cucuacaccc gccacaggau caggauccgc aaucgcuucu ggaguagccg      420

uuugcaaagu auuacaccua gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa      480

cuaauaaagc aguaguauca cuuucuaaug guguaucagu auuaacauuc aaaguccucg      540

accuaaaaaa uuacaucgac aaacaacuau uacccauccu uaauaaacaa ucaugcucca      600

uaucaaacau agaaacuguc auggaauuuc aacaaaaaaa caauagacuu cuagaaauca      660

caagagaauu uucuguaaau gcaggaguaa cuacaccagu aucaacauau auguuaacca      720

acuccgaacu acuaucacuc auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa      780

ugucaaauaa cguucaaaua guaagacaac aaucauacuc aaucaugugc auaauaaaag      840

aagaaguuuu agcauacguc guacaacuuc cccuauacgg aguaauagac accccuugcu      900

ggaaacucca caccucacca cuaugcacua caaacacaaa agaagguucc aacaucugcu      960

uaacaagaac cgaucgagga ugguacugcg acaacgcugg uuccguaucu uucuucccac     1020

aagcagaaac augcaaagua ugcuccaaua gaguauucug cgacaccaug aacucacuaa     1080

cucuaccauc cgaaguaaac cuaugcaacg ucgacauauu uaauccaaaa uaugacugca     1140

aaauaaugac uucaaaaaca gacguauccu caucaguaau aacauccuua ggagcaauag     1200

uaucauguua cggcaagaca aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa     1260

ccuucuccaa cggcugcgac uacguaucaa auaaaggugu cgauacagua ucaguaggaa     1320

acacacucua uuacguuaau aaacaagaag gaaagucauu auacguaaaa ggagaaccaa     1380

uaaucaauuu cuacgauccc cuagucuuuc ccucagauga auuugacgca agcaucucuc     1440

aagucaacga aaaaauaaac caaucccuag ccuucauaag aaaaucagau gaacuacuuc     1500

auaacgucaa cgccggaaaa ucaacaacca acauaaugau cacuacaauc auaauuguaa     1560

uuauaguaau acuacuaucg cuaauugccg uuggacuacu acuauauugu aaagcaagau     1620

caacacccgu uacucuaucc aaagaucaau uaucaggaau caacaacaua gccuucucaa     1680

auuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7050
<211>  2180
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7050
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uacuuaaagc caacgcaaua accacaaucc      120

ucaccgccgu cacauucugc uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu      180

cuaccugcuc cgccgucucc aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca      240

gcguuaucac caucgaacua ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa      300

aagucaaacu caucaaacaa gaacuagaca aauacaagaa ugccgucacc gaacuacaaa      360

ugcucaugug cuccaccccc gccaccggau ccggcuccgc cauugccucc ggcgucgccg      420

uaugcaaagu ccuucacuug gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga      480

ccaacaaagc gguggucagc cucuccaacg gcgucucugu ccucaccuuc aaaguccucg      540

accucaagaa cuacauagau aaacaacuac uccccauccu aaacaaacag ucaugcagca      600

uauccaacau cgaaaccguc auggaguucc aacagaaaaa caaccgccuc cuugaaauca      660

cccgcgaguu cucugucaac gccggcguca ccacccccgu cuccaccuac augcucacaa      720

acuccgaacu ccucagccuc aucaacgaca ugccaaucac caacgaccaa aagaaacuca      780

uguccaacaa cguacaaauc guucgucaac aaucauacuc aaucaugugc aucauuaaag      840

aagaaguccu cgcauacguc guccaacucc cccucuaugg ggucaucgac accccaugcu      900

ggaaacucca caccucuccc cuaugcacca ccaacaccaa agaaggcucc aacaucugcc      960

uaacccgaac cgaccgcgga ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgaaac auguaaaguc ugcuccaacc guguguucug cgacaccaug aacucacuaa     1080

cccuccccuc cgaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaauaaugac cagcaaaaca gacguauccu cuagcgucau uaccagccua ggugcaaucg     1200

uguccugcua cggcaaaaca aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa     1260

ccuucuccaa cggcugcgac uacgucagca acaaaggagu cgacaccguc uccguaggaa     1320

auacucuaua cuaugucaac aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccucugacga guucgacgcc agcauaucac     1440

aaguaaacga aaagaucaac caaucccucg cauucauucg caaauccgac gaacuccuac     1500

acaacgucaa cgccggaaaa uccaccacca acaucaugau cacuacuauc auuaucguca     1560

ucaucgucau ccuccucucc cucaucgcag ucggccuucu acucuacugc aaggcacgcu     1620

cuacacccgu aacccugucu aaagaccaac ucuccggcau caacaacauc gcuuucucca     1680

acuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1740

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1800

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1860

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1920

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1980

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     2040

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2160

uuuucagagc caccagaauu                                                 2180


<210>  7051
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7051
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7052
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7052
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cuccaccccg     1620

gugacccuga gcaaggacca gcuguccggg aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7053
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7053
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7054
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7054
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gucuacaccg     1620

gugaccuuga gcaaagacca gcuguccggc aucaacaaua uagcuuucuc aaacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7055
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7055
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7056
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7056
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cuccacaccu     1620

gugacccuga gcaaagacca gcuuucuggg aucaacaaua uugcguucuc caacugagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7057
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7057
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacucaaa gcaaaugcaa uuaccacuau acucacagcu      120

guaacuuuuu guuucgccuc aggacaaaac aucacagaag aauuuuauca auccacaugc      180

ucugccguau caaaaggcua ccuaucugcc cuaagaacag guugguacac aucuguaaua      240

acaaucgaau uauccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaaac aagaauuaga uaaauauaaa aacgcaguaa cagaacuaca aaugcuaaug      360

ugcucuacac ccgccacagg aucaggaucc gcaaucgcuu cuggaguagc cguuugcaaa      420

guauuacacc uagaaggaga aguaaauaaa auaaaauccg cacuacuauc aacuaauaaa      480

gcaguaguau cacuuucuaa ugguguauca guauuaacau ucaaaguccu cgaccuaaaa      540

aauuacaucg acaaacaacu auuacccauc cuuaauaaac aaucaugcuc cauaucaaac      600

auagaaacug ucauggaauu ucaacaaaaa aacaauagac uucuagaaau cacaagagaa      660

uuuucuguaa augcaggagu aacuacacca guaucaacau auauguuaac caacuccgaa      720

cuacuaucac ucauaaacga caugccaaua acaaacgacc aaaaaaaacu aaugucaaau      780

aacguucaaa uaguaagaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu uccccuauac ggaguaauag acaccccuug cuggaaacuc      900

cacaccucac cacuaugcac uacaaacaca aaagaagguu ccaacaucug cuuaacaaga      960

accgaucgag gaugguacug cgacaacgcu gguuccguau cuuucuuccc acaagcagaa     1020

acaugcaaag uaugcuccaa uagaguauuc ugcgacacca ugaacucacu aacucuacca     1080

uccgaaguaa accuaugcaa cgucgacaua uuuaauccaa aauaugacug caaaauaaug     1140

acuucaaaaa cagacguauc cucaucagua auaacauccu uaggagcaau aguaucaugu     1200

uacggcaaga caaaauguac agccucaaac aaaaacaaag guaucauuaa aaccuucucc     1260

aacggcugcg acuacguauc aaauaaaggu gucgauacag uaucaguagg aaacacacuc     1320

uauuacguua auaaacaaga aggaaaguca uuauacguaa aaggagaacc aauaaucaau     1380

uucuacgauc cccuagucuu ucccucagau gaauuugacg caagcaucuc ucaagucaac     1440

gaaaaaauaa accaaucccu agccuucaua agaaaaucag augaacuacu ucauaacguc     1500

aacgccggaa aaucaacaac caacauaaug aucacuacaa ucauaauugu aauuauagua     1560

auacuacuau cgcuaauugc cguuggacua cuacuauauu guaaagcaag aucaacaccc     1620

guuacucuau ccaaagauca auuaucagga aucaacaaca uagccuucuc aaauuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7058
<211>  1956
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7058
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuuaaa gccaacgcaa uaaccacaau ccucaccgcc      120

gucacauucu gcuucgccuc gggacaaaac auaaccgaag aauuuuacca gucuaccugc      180

uccgccgucu ccaaggguua ccucuccgcg cuccgcaccg ggugguacac cagcguuauc      240

accaucgaac uaucuaacau aaaagaaaac aagugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaag aaugccguca ccgaacuaca aaugcucaug      360

ugcuccaccc ccgccaccgg auccggcucc gccauugccu ccggcgucgc cguaugcaaa      420

guccuucacu uggaaggaga aguuaacaaa auaaaaagcg cccuccuguc gaccaacaaa      480

gcggugguca gccucuccaa cggcgucucu guccucaccu ucaaaguccu cgaccucaag      540

aacuacauag auaaacaacu acuccccauc cuaaacaaac agucaugcag cauauccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaccgcc uccuugaaau cacccgcgag      660

uucucuguca acgccggcgu caccaccccc gucuccaccu acaugcucac aaacuccgaa      720

cuccucagcc ucaucaacga caugccaauc accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucguca acaaucauac ucaaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg ucguccaacu cccccucuau ggggucaucg acaccccaug cuggaaacuc      900

cacaccucuc cccuaugcac caccaacacc aaagaaggcu ccaacaucug ccuaacccga      960

accgaccgcg gaugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgaa     1020

acauguaaag ucugcuccaa ccguguguuc ugcgacacca ugaacucacu aacccucccc     1080

uccgaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaauaaug     1140

accagcaaaa cagacguauc cucuagcguc auuaccagcc uaggugcaau cguguccugc     1200

uacggcaaaa caaaaugcac cgccuccaac aaaaauaaag gaaucauaaa aaccuucucc     1260

aacggcugcg acuacgucag caacaaagga gucgacaccg ucuccguagg aaauacucua     1320

uacuauguca acaaacaaga ggguaaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccucugac gaguucgacg ccagcauauc acaaguaaac     1440

gaaaagauca accaaucccu cgcauucauu cgcaaauccg acgaacuccu acacaacguc     1500

aacgccggaa aauccaccac caacaucaug aucacuacua ucauuaucgu caucaucguc     1560

auccuccucu cccucaucgc agucggccuu cuacucuacu gcaaggcacg cucuacaccc     1620

guaacccugu cuaaagacca acucuccggc aucaacaaca ucgcuuucuc caacuaagga     1680

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1740

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1800

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1920

ccccccccaa aggcucuuuu cagagccacc agaauu                               1956


<210>  7059
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7059
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gagcacgccc     1620

gucacccugu ccaaggacca gcugagcggc aucaacaaca ucgcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7060
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7060
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cuccaccccg     1620

gugacccuga gcaaggacca gcuguccggg aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7061
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7061
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cuccaccccc     1620

gucacccucu ccaaggacca gcucuccggc aucaacaaca ucgccuucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7062
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7062
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gucuacaccg     1620

gugaccuuga gcaaagacca gcuguccggc aucaacaaua uagcuuucuc aaacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7063
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7063
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag aagcaccccc     1620

gugacccuga gcaaggacca gcugagcggc aucaacaaca ucgccuucag caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7064
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7064
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cuccacaccu     1620

gugacccuga gcaaagacca gcuuucuggg aucaacaaua uugcguucuc caacugagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7065
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7065
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu cauacucaaa gcaaaugcaa uuaccacuau acucacagcu      120

guaacuuuuu guuucgccuc aggacaaaac aucacagaag aauuuuauca auccacaugc      180

ucugccguau caaaaggcua ccuaucugcc cuaagaacag guugguacac aucuguaaua      240

acaaucgaau uauccaacau caaagaaaac aaaugcaacg gcacagacgc aaaagucaaa      300

cucaucaaac aagaauuaga uaaauauaaa aacgcaguaa cagaacuaca aaugcuaaug      360

ugcucuacac ccgccacagg aucaggaucc gcaaucgcuu cuggaguagc cguuugcaaa      420

guauuacacc uagaaggaga aguaaauaaa auaaaauccg cacuacuauc aacuaauaaa      480

gcaguaguau cacuuucuaa ugguguauca guauuaacau ucaaaguccu cgaccuaaaa      540

aauuacaucg acaaacaacu auuacccauc cuuaauaaac aaucaugcuc cauaucaaac      600

auagaaacug ucauggaauu ucaacaaaaa aacaauagac uucuagaaau cacaagagaa      660

uuuucuguaa augcaggagu aacuacacca guaucaacau auauguuaac caacuccgaa      720

cuacuaucac ucauaaacga caugccaaua acaaacgacc aaaaaaaacu aaugucaaau      780

aacguucaaa uaguaagaca acaaucauac ucaaucaugu gcauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu uccccuauac ggaguaauag acaccccuug cuggaaacuc      900

cacaccucac cacuaugcac uacaaacaca aaagaagguu ccaacaucug cuuaacaaga      960

accgaucgag gaugguacug cgacaacgcu gguuccguau cuuucuuccc acaagcagaa     1020

acaugcaaag uaugcuccaa uagaguauuc ugcgacacca ugaacucacu aacucuacca     1080

uccgaaguaa accuaugcaa cgucgacaua uuuaauccaa aauaugacug caaaauaaug     1140

acuucaaaaa cagacguauc cucaucagua auaacauccu uaggagcaau aguaucaugu     1200

uacggcaaga caaaauguac agccucaaac aaaaacaaag guaucauuaa aaccuucucc     1260

aacggcugcg acuacguauc aaauaaaggu gucgauacag uaucaguagg aaacacacuc     1320

uauuacguua auaaacaaga aggaaaguca uuauacguaa aaggagaacc aauaaucaau     1380

uucuacgauc cccuagucuu ucccucagau gaauuugacg caagcaucuc ucaagucaac     1440

gaaaaaauaa accaaucccu agccuucaua agaaaaucag augaacuacu ucauaacguc     1500

aacgccggaa aaucaacaac caacauaaug aucacuacaa ucauaauugu aauuauagua     1560

auacuacuau cgcuaauugc cguuggacua cuacuauauu guaaagcaag aucaacaccc     1620

guuacucuau ccaaagauca auuaucagga aucaacaaca uagccuucuc aaauuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7066
<211>  1952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7066
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauacuuaaa gccaacgcaa uaaccacaau ccucaccgcc      120

gucacauucu gcuucgccuc gggacaaaac auaaccgaag aauuuuacca gucuaccugc      180

uccgccgucu ccaaggguua ccucuccgcg cuccgcaccg ggugguacac cagcguuauc      240

accaucgaac uaucuaacau aaaagaaaac aagugcaacg gaaccgacgc aaaagucaaa      300

cucaucaaac aagaacuaga caaauacaag aaugccguca ccgaacuaca aaugcucaug      360

ugcuccaccc ccgccaccgg auccggcucc gccauugccu ccggcgucgc cguaugcaaa      420

guccuucacu uggaaggaga aguuaacaaa auaaaaagcg cccuccuguc gaccaacaaa      480

gcggugguca gccucuccaa cggcgucucu guccucaccu ucaaaguccu cgaccucaag      540

aacuacauag auaaacaacu acuccccauc cuaaacaaac agucaugcag cauauccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaccgcc uccuugaaau cacccgcgag      660

uucucuguca acgccggcgu caccaccccc gucuccaccu acaugcucac aaacuccgaa      720

cuccucagcc ucaucaacga caugccaauc accaacgacc aaaagaaacu cauguccaac      780

aacguacaaa ucguucguca acaaucauac ucaaucaugu gcaucauuaa agaagaaguc      840

cucgcauacg ucguccaacu cccccucuau ggggucaucg acaccccaug cuggaaacuc      900

cacaccucuc cccuaugcac caccaacacc aaagaaggcu ccaacaucug ccuaacccga      960

accgaccgcg gaugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgaa     1020

acauguaaag ucugcuccaa ccguguguuc ugcgacacca ugaacucacu aacccucccc     1080

uccgaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaauaaug     1140

accagcaaaa cagacguauc cucuagcguc auuaccagcc uaggugcaau cguguccugc     1200

uacggcaaaa caaaaugcac cgccuccaac aaaaauaaag gaaucauaaa aaccuucucc     1260

aacggcugcg acuacgucag caacaaagga gucgacaccg ucuccguagg aaauacucua     1320

uacuauguca acaaacaaga ggguaaaucc cucuacguca aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccucugac gaguucgacg ccagcauauc acaaguaaac     1440

gaaaagauca accaaucccu cgcauucauu cgcaaauccg acgaacuccu acacaacguc     1500

aacgccggaa aauccaccac caacaucaug aucacuacua ucauuaucgu caucaucguc     1560

auccuccucu cccucaucgc agucggccuu cuacucuacu gcaaggcacg cucuacaccc     1620

guaacccugu cuaaagacca acucuccggc aucaacaaca ucgcuuucuc caacuaagga     1680

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1740

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1800

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1920

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1952


<210>  7067
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7067
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7068
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7068
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcuc caccccggug acccugagca aggaccagcu guccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7069
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7069
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7070
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7070
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacgguc uacaccggug accuugagca aagaccagcu guccggcauc     1680

aacaauauag cuuucucaaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7071
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7071
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7072
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7072
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcuc cacaccugug acccugagca aagaccagcu uucugggauc     1680

aacaauauug cguucuccaa cugaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7073
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7073
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acucaaagca      120

aaugcaauua ccacuauacu cacagcugua acuuuuuguu ucgccucagg acaaaacauc      180

acagaagaau uuuaucaauc cacaugcucu gccguaucaa aaggcuaccu aucugcccua      240

agaacagguu gguacacauc uguaauaaca aucgaauuau ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaaacaag aauuagauaa auauaaaaac      360

gcaguaacag aacuacaaau gcuaaugugc ucuacacccg ccacaggauc aggauccgca      420

aucgcuucug gaguagccgu uugcaaagua uuacaccuag aaggagaagu aaauaaaaua      480

aaauccgcac uacuaucaac uaauaaagca guaguaucac uuucuaaugg uguaucagua      540

uuaacauuca aaguccucga ccuaaaaaau uacaucgaca aacaacuauu acccauccuu      600

aauaaacaau caugcuccau aucaaacaua gaaacuguca uggaauuuca acaaaaaaac      660

aauagacuuc uagaaaucac aagagaauuu ucuguaaaug caggaguaac uacaccagua      720

ucaacauaua uguuaaccaa cuccgaacua cuaucacuca uaaacgacau gccaauaaca      780

aacgaccaaa aaaaacuaau gucaaauaac guucaaauag uaagacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguuuua gcauacgucg uacaacuucc ccuauacgga      900

guaauagaca ccccuugcug gaaacuccac accucaccac uaugcacuac aaacacaaaa      960

gaagguucca acaucugcuu aacaagaacc gaucgaggau gguacugcga caacgcuggu     1020

uccguaucuu ucuucccaca agcagaaaca ugcaaaguau gcuccaauag aguauucugc     1080

gacaccauga acucacuaac ucuaccaucc gaaguaaacc uaugcaacgu cgacauauuu     1140

aauccaaaau augacugcaa aauaaugacu ucaaaaacag acguauccuc aucaguaaua     1200

acauccuuag gagcaauagu aucauguuac ggcaagacaa aauguacagc cucaaacaaa     1260

aacaaaggua ucauuaaaac cuucuccaac ggcugcgacu acguaucaaa uaaagguguc     1320

gauacaguau caguaggaaa cacacucuau uacguuaaua aacaagaagg aaagucauua     1380

uacguaaaag gagaaccaau aaucaauuuc uacgaucccc uagucuuucc cucagaugaa     1440

uuugacgcaa gcaucucuca agucaacgaa aaaauaaacc aaucccuagc cuucauaaga     1500

aaaucagaug aacuacuuca uaacgucaac gccggaaaau caacaaccaa cauaaugauc     1560

acuacaauca uaauuguaau uauaguaaua cuacuaucgc uaauugccgu uggacuacua     1620

cuauauugua aagcaagauc aacacccguu acucuaucca aagaucaauu aucaggaauc     1680

aacaacauag ccuucucaaa uuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7074
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7074
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuuaaagcc      120

aacgcaauaa ccacaauccu caccgccguc acauucugcu ucgccucggg acaaaacaua      180

accgaagaau uuuaccaguc uaccugcucc gccgucucca aggguuaccu cuccgcgcuc      240

cgcaccgggu gguacaccag cguuaucacc aucgaacuau cuaacauaaa agaaaacaag      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaagaau      360

gccgucaccg aacuacaaau gcucaugugc uccacccccg ccaccggauc cggcuccgcc      420

auugccuccg gcgucgccgu augcaaaguc cuucacuugg aaggagaagu uaacaaaaua      480

aaaagcgccc uccugucgac caacaaagcg guggucagcc ucuccaacgg cgucucuguc      540

cucaccuuca aaguccucga ccucaagaac uacauagaua aacaacuacu ccccauccua      600

aacaaacagu caugcagcau auccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaccgccucc uugaaaucac ccgcgaguuc ucugucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucacaaa cuccgaacuc cucagccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgucaaca aucauacuca      840

aucaugugca ucauuaaaga agaaguccuc gcauacgucg uccaacuccc ccucuauggg      900

gucaucgaca ccccaugcug gaaacuccac accucucccc uaugcaccac caacaccaaa      960

gaaggcucca acaucugccu aacccgaacc gaccgcggau gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgaaaca uguaaagucu gcuccaaccg uguguucugc     1080

gacaccauga acucacuaac ccuccccucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aauaaugacc agcaaaacag acguauccuc uagcgucauu     1200

accagccuag gugcaaucgu guccugcuac ggcaaaacaa aaugcaccgc cuccaacaaa     1260

aauaaaggaa ucauaaaaac cuucuccaac ggcugcgacu acgucagcaa caaaggaguc     1320

gacaccgucu ccguaggaaa uacucuauac uaugucaaca aacaagaggg uaaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cucugacgag     1440

uucgacgcca gcauaucaca aguaaacgaa aagaucaacc aaucccucgc auucauucgc     1500

aaauccgacg aacuccuaca caacgucaac gccggaaaau ccaccaccaa caucaugauc     1560

acuacuauca uuaucgucau caucgucauc cuccucuccc ucaucgcagu cggccuucua     1620

cucuacugca aggcacgcuc uacacccgua acccugucua aagaccaacu cuccggcauc     1680

aacaacaucg cuuucuccaa cuaaggacua guaauaagga aacuguauga augucugugg     1740

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1800

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7075
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7075
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggag cacgcccguc acccugucca aggaccagcu gagcggcauc     1680

aacaacaucg cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7076
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7076
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcuc caccccggug acccugagca aggaccagcu guccgggauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7077
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7077
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcuc cacccccguc acccucucca aggaccagcu cuccggcauc     1680

aacaacaucg ccuucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7078
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7078
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacgguc uacaccggug accuugagca aagaccagcu guccggcauc     1680

aacaauauag cuuucucaaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7079
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7079
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaag cacccccgug acccugagca aggaccagcu gagcggcauc     1680

aacaacaucg ccuucagcaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7080
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7080
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcuc cacaccugug acccugagca aagaccagcu uucugggauc     1680

aacaauauug cguucuccaa cugaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7081
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7081
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacucau acucaaagca      120

aaugcaauua ccacuauacu cacagcugua acuuuuuguu ucgccucagg acaaaacauc      180

acagaagaau uuuaucaauc cacaugcucu gccguaucaa aaggcuaccu aucugcccua      240

agaacagguu gguacacauc uguaauaaca aucgaauuau ccaacaucaa agaaaacaaa      300

ugcaacggca cagacgcaaa agucaaacuc aucaaacaag aauuagauaa auauaaaaac      360

gcaguaacag aacuacaaau gcuaaugugc ucuacacccg ccacaggauc aggauccgca      420

aucgcuucug gaguagccgu uugcaaagua uuacaccuag aaggagaagu aaauaaaaua      480

aaauccgcac uacuaucaac uaauaaagca guaguaucac uuucuaaugg uguaucagua      540

uuaacauuca aaguccucga ccuaaaaaau uacaucgaca aacaacuauu acccauccuu      600

aauaaacaau caugcuccau aucaaacaua gaaacuguca uggaauuuca acaaaaaaac      660

aauagacuuc uagaaaucac aagagaauuu ucuguaaaug caggaguaac uacaccagua      720

ucaacauaua uguuaaccaa cuccgaacua cuaucacuca uaaacgacau gccaauaaca      780

aacgaccaaa aaaaacuaau gucaaauaac guucaaauag uaagacaaca aucauacuca      840

aucaugugca uaauaaaaga agaaguuuua gcauacgucg uacaacuucc ccuauacgga      900

guaauagaca ccccuugcug gaaacuccac accucaccac uaugcacuac aaacacaaaa      960

gaagguucca acaucugcuu aacaagaacc gaucgaggau gguacugcga caacgcuggu     1020

uccguaucuu ucuucccaca agcagaaaca ugcaaaguau gcuccaauag aguauucugc     1080

gacaccauga acucacuaac ucuaccaucc gaaguaaacc uaugcaacgu cgacauauuu     1140

aauccaaaau augacugcaa aauaaugacu ucaaaaacag acguauccuc aucaguaaua     1200

acauccuuag gagcaauagu aucauguuac ggcaagacaa aauguacagc cucaaacaaa     1260

aacaaaggua ucauuaaaac cuucuccaac ggcugcgacu acguaucaaa uaaagguguc     1320

gauacaguau caguaggaaa cacacucuau uacguuaaua aacaagaagg aaagucauua     1380

uacguaaaag gagaaccaau aaucaauuuc uacgaucccc uagucuuucc cucagaugaa     1440

uuugacgcaa gcaucucuca agucaacgaa aaaauaaacc aaucccuagc cuucauaaga     1500

aaaucagaug aacuacuuca uaacgucaac gccggaaaau caacaaccaa cauaaugauc     1560

acuacaauca uaauuguaau uauaguaaua cuacuaucgc uaauugccgu uggacuacua     1620

cuauauugua aagcaagauc aacacccguu acucuaucca aagaucaauu aucaggaauc     1680

aacaacauag ccuucucaaa uuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7082
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7082
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau acuuaaagcc      120

aacgcaauaa ccacaauccu caccgccguc acauucugcu ucgccucggg acaaaacaua      180

accgaagaau uuuaccaguc uaccugcucc gccgucucca aggguuaccu cuccgcgcuc      240

cgcaccgggu gguacaccag cguuaucacc aucgaacuau cuaacauaaa agaaaacaag      300

ugcaacggaa ccgacgcaaa agucaaacuc aucaaacaag aacuagacaa auacaagaau      360

gccgucaccg aacuacaaau gcucaugugc uccacccccg ccaccggauc cggcuccgcc      420

auugccuccg gcgucgccgu augcaaaguc cuucacuugg aaggagaagu uaacaaaaua      480

aaaagcgccc uccugucgac caacaaagcg guggucagcc ucuccaacgg cgucucuguc      540

cucaccuuca aaguccucga ccucaagaac uacauagaua aacaacuacu ccccauccua      600

aacaaacagu caugcagcau auccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaccgccucc uugaaaucac ccgcgaguuc ucugucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucacaaa cuccgaacuc cucagccuca ucaacgacau gccaaucacc      780

aacgaccaaa agaaacucau guccaacaac guacaaaucg uucgucaaca aucauacuca      840

aucaugugca ucauuaaaga agaaguccuc gcauacgucg uccaacuccc ccucuauggg      900

gucaucgaca ccccaugcug gaaacuccac accucucccc uaugcaccac caacaccaaa      960

gaaggcucca acaucugccu aacccgaacc gaccgcggau gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgaaaca uguaaagucu gcuccaaccg uguguucugc     1080

gacaccauga acucacuaac ccuccccucc gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aauaaugacc agcaaaacag acguauccuc uagcgucauu     1200

accagccuag gugcaaucgu guccugcuac ggcaaaacaa aaugcaccgc cuccaacaaa     1260

aauaaaggaa ucauaaaaac cuucuccaac ggcugcgacu acgucagcaa caaaggaguc     1320

gacaccgucu ccguaggaaa uacucuauac uaugucaaca aacaagaggg uaaaucccuc     1380

uacgucaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cucugacgag     1440

uucgacgcca gcauaucaca aguaaacgaa aagaucaacc aaucccucgc auucauucgc     1500

aaauccgacg aacuccuaca caacgucaac gccggaaaau ccaccaccaa caucaugauc     1560

acuacuauca uuaucgucau caucgucauc cuccucuccc ucaucgcagu cggccuucua     1620

cucuacugca aggcacgcuc uacacccgua acccugucua aagaccaacu cuccggcauc     1680

aacaacaucg cuuucuccaa cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1740

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1800

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1860

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1920

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1980

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     2040

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2160

cccccccccc caaaggcucu uuucagagcc accagaauu                            2199


<210>  7083
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7083
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1680

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7084
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7084
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcuccac cccggugacc     1680

cugagcaagg accagcuguc cgggaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7085
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7085
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1680

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7086
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7086
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggucuac accggugacc     1680

uugagcaaag accagcuguc cggcaucaac aauauagcuu ucucaaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7087
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7087
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1680

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7088
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7088
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcuccac accugugacc     1680

cugagcaaag accagcuuuc ugggaucaac aauauugcgu ucuccaacug aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7089
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7089
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacucauacu caaagcaaau gcaauuacca cuauacucac agcuguaacu      180

uuuuguuucg ccucaggaca aaacaucaca gaagaauuuu aucaauccac augcucugcc      240

guaucaaaag gcuaccuauc ugcccuaaga acagguuggu acacaucugu aauaacaauc      300

gaauuaucca acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc      360

aaacaagaau uagauaaaua uaaaaacgca guaacagaac uacaaaugcu aaugugcucu      420

acacccgcca caggaucagg auccgcaauc gcuucuggag uagccguuug caaaguauua      480

caccuagaag gagaaguaaa uaaaauaaaa uccgcacuac uaucaacuaa uaaagcagua      540

guaucacuuu cuaauggugu aucaguauua acauucaaag uccucgaccu aaaaaauuac      600

aucgacaaac aacuauuacc cauccuuaau aaacaaucau gcuccauauc aaacauagaa      660

acugucaugg aauuucaaca aaaaaacaau agacuucuag aaaucacaag agaauuuucu      720

guaaaugcag gaguaacuac accaguauca acauauaugu uaaccaacuc cgaacuacua      780

ucacucauaa acgacaugcc aauaacaaac gaccaaaaaa aacuaauguc aaauaacguu      840

caaauaguaa gacaacaauc auacucaauc augugcauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuuccccu auacggagua auagacaccc cuugcuggaa acuccacacc      960

ucaccacuau gcacuacaaa cacaaaagaa gguuccaaca ucugcuuaac aagaaccgau     1020

cgaggauggu acugcgacaa cgcugguucc guaucuuucu ucccacaagc agaaacaugc     1080

aaaguaugcu ccaauagagu auucugcgac accaugaacu cacuaacucu accauccgaa     1140

guaaaccuau gcaacgucga cauauuuaau ccaaaauaug acugcaaaau aaugacuuca     1200

aaaacagacg uauccucauc aguaauaaca uccuuaggag caauaguauc auguuacggc     1260

aagacaaaau guacagccuc aaacaaaaac aaagguauca uuaaaaccuu cuccaacggc     1320

ugcgacuacg uaucaaauaa aggugucgau acaguaucag uaggaaacac acucuauuac     1380

guuaauaaac aagaaggaaa gucauuauac guaaaaggag aaccaauaau caauuucuac     1440

gauccccuag ucuuucccuc agaugaauuu gacgcaagca ucucucaagu caacgaaaaa     1500

auaaaccaau cccuagccuu cauaagaaaa ucagaugaac uacuucauaa cgucaacgcc     1560

ggaaaaucaa caaccaacau aaugaucacu acaaucauaa uuguaauuau aguaauacua     1620

cuaucgcuaa uugccguugg acuacuacua uauuguaaag caagaucaac acccguuacu     1680

cuauccaaag aucaauuauc aggaaucaac aacauagccu ucucaaauua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7090
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7090
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauacu uaaagccaac gcaauaacca caauccucac cgccgucaca      180

uucugcuucg ccucgggaca aaacauaacc gaagaauuuu accagucuac cugcuccgcc      240

gucuccaagg guuaccucuc cgcgcuccgc accggguggu acaccagcgu uaucaccauc      300

gaacuaucua acauaaaaga aaacaagugc aacggaaccg acgcaaaagu caaacucauc      360

aaacaagaac uagacaaaua caagaaugcc gucaccgaac uacaaaugcu caugugcucc      420

acccccgcca ccggauccgg cuccgccauu gccuccggcg ucgccguaug caaaguccuu      480

cacuuggaag gagaaguuaa caaaauaaaa agcgcccucc ugucgaccaa caaagcggug      540

gucagccucu ccaacggcgu cucuguccuc accuucaaag uccucgaccu caagaacuac      600

auagauaaac aacuacuccc cauccuaaac aaacagucau gcagcauauc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaac cgccuccuug aaaucacccg cgaguucucu      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucacaaacuc cgaacuccuc      780

agccucauca acgacaugcc aaucaccaac gaccaaaaga aacucauguc caacaacgua      840

caaaucguuc gucaacaauc auacucaauc augugcauca uuaaagaaga aguccucgca      900

uacgucgucc aacucccccu cuaugggguc aucgacaccc caugcuggaa acuccacacc      960

ucuccccuau gcaccaccaa caccaaagaa ggcuccaaca ucugccuaac ccgaaccgac     1020

cgcggauggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgaaacaugu     1080

aaagucugcu ccaaccgugu guucugcgac accaugaacu cacuaacccu ccccuccgaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau aaugaccagc     1200

aaaacagacg uauccucuag cgucauuacc agccuaggug caaucguguc cugcuacggc     1260

aaaacaaaau gcaccgccuc caacaaaaau aaaggaauca uaaaaaccuu cuccaacggc     1320

ugcgacuacg ucagcaacaa aggagucgac accgucuccg uaggaaauac ucuauacuau     1380

gucaacaaac aagaggguaa aucccucuac gucaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc ugacgaguuc gacgccagca uaucacaagu aaacgaaaag     1500

aucaaccaau cccucgcauu cauucgcaaa uccgacgaac uccuacacaa cgucaacgcc     1560

ggaaaaucca ccaccaacau caugaucacu acuaucauua ucgucaucau cgucauccuc     1620

cucucccuca ucgcagucgg ccuucuacuc uacugcaagg cacgcucuac acccguaacc     1680

cugucuaaag accaacucuc cggcaucaac aacaucgcuu ucuccaacua aggacuagua     1740

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1800

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7091
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7091
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7092
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7092
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cuccaccccg gugacccuga gcaaggacca gcuguccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7093
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7093
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7094
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7094
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gucuacaccg gugaccuuga gcaaagacca gcuguccggc     1680

aucaacaaua uagcuuucuc aaacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7095
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7095
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7096
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7096
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cuccacaccu gugacccuga gcaaagacca gcuuucuggg     1680

aucaacaaua uugcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7097
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7097
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacucaaa      120

gcaaaugcaa uuaccacuau acucacagcu guaacuuuuu guuucgccuc aggacaaaac      180

aucacagaag aauuuuauca auccacaugc ucugccguau caaaaggcua ccuaucugcc      240

cuaagaacag guugguacac aucuguaaua acaaucgaau uauccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaaac aagaauuaga uaaauauaaa      360

aacgcaguaa cagaacuaca aaugcuaaug ugcucuacac ccgccacagg aucaggaucc      420

gcaaucgcuu cuggaguagc cguuugcaaa guauuacacc uagaaggaga aguaaauaaa      480

auaaaauccg cacuacuauc aacuaauaaa gcaguaguau cacuuucuaa ugguguauca      540

guauuaacau ucaaaguccu cgaccuaaaa aauuacaucg acaaacaacu auuacccauc      600

cuuaauaaac aaucaugcuc cauaucaaac auagaaacug ucauggaauu ucaacaaaaa      660

aacaauagac uucuagaaau cacaagagaa uuuucuguaa augcaggagu aacuacacca      720

guaucaacau auauguuaac caacuccgaa cuacuaucac ucauaaacga caugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguucaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguu uuagcauacg ucguacaacu uccccuauac      900

ggaguaauag acaccccuug cuggaaacuc cacaccucac cacuaugcac uacaaacaca      960

aaagaagguu ccaacaucug cuuaacaaga accgaucgag gaugguacug cgacaacgcu     1020

gguuccguau cuuucuuccc acaagcagaa acaugcaaag uaugcuccaa uagaguauuc     1080

ugcgacacca ugaacucacu aacucuacca uccgaaguaa accuaugcaa cgucgacaua     1140

uuuaauccaa aauaugacug caaaauaaug acuucaaaaa cagacguauc cucaucagua     1200

auaacauccu uaggagcaau aguaucaugu uacggcaaga caaaauguac agccucaaac     1260

aaaaacaaag guaucauuaa aaccuucucc aacggcugcg acuacguauc aaauaaaggu     1320

gucgauacag uaucaguagg aaacacacuc uauuacguua auaaacaaga aggaaaguca     1380

uuauacguaa aaggagaacc aauaaucaau uucuacgauc cccuagucuu ucccucagau     1440

gaauuugacg caagcaucuc ucaagucaac gaaaaaauaa accaaucccu agccuucaua     1500

agaaaaucag augaacuacu ucauaacguc aacgccggaa aaucaacaac caacauaaug     1560

aucacuacaa ucauaauugu aauuauagua auacuacuau cgcuaauugc cguuggacua     1620

cuacuauauu guaaagcaag aucaacaccc guuacucuau ccaaagauca auuaucagga     1680

aucaacaaca uagccuucuc aaauuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7098
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7098
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuuaaa      120

gccaacgcaa uaaccacaau ccucaccgcc gucacauucu gcuucgccuc gggacaaaac      180

auaaccgaag aauuuuacca gucuaccugc uccgccgucu ccaaggguua ccucuccgcg      240

cuccgcaccg ggugguacac cagcguuauc accaucgaac uaucuaacau aaaagaaaac      300

aagugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaag      360

aaugccguca ccgaacuaca aaugcucaug ugcuccaccc ccgccaccgg auccggcucc      420

gccauugccu ccggcgucgc cguaugcaaa guccuucacu uggaaggaga aguuaacaaa      480

auaaaaagcg cccuccuguc gaccaacaaa gcggugguca gccucuccaa cggcgucucu      540

guccucaccu ucaaaguccu cgaccucaag aacuacauag auaaacaacu acuccccauc      600

cuaaacaaac agucaugcag cauauccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaccgcc uccuugaaau cacccgcgag uucucuguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucguca acaaucauac      840

ucaaucaugu gcaucauuaa agaagaaguc cucgcauacg ucguccaacu cccccucuau      900

ggggucaucg acaccccaug cuggaaacuc cacaccucuc cccuaugcac caccaacacc      960

aaagaaggcu ccaacaucug ccuaacccga accgaccgcg gaugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgaa acauguaaag ucugcuccaa ccguguguuc     1080

ugcgacacca ugaacucacu aacccucccc uccgaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaauaaug accagcaaaa cagacguauc cucuagcguc     1200

auuaccagcc uaggugcaau cguguccugc uacggcaaaa caaaaugcac cgccuccaac     1260

aaaaauaaag gaaucauaaa aaccuucucc aacggcugcg acuacgucag caacaaagga     1320

gucgacaccg ucuccguagg aaauacucua uacuauguca acaaacaaga ggguaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccucugac     1440

gaguucgacg ccagcauauc acaaguaaac gaaaagauca accaaucccu cgcauucauu     1500

cgcaaauccg acgaacuccu acacaacguc aacgccggaa aauccaccac caacaucaug     1560

aucacuacua ucauuaucgu caucaucguc auccuccucu cccucaucgc agucggccuu     1620

cuacucuacu gcaaggcacg cucuacaccc guaacccugu cuaaagacca acucuccggc     1680

aucaacaaca ucgcuuucuc caacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7099
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7099
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7100
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7100
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cuccaccccg gugacccuga gcaaggacca gcuguccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7101
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7101
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7102
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7102
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gucuacaccg gugaccuuga gcaaagacca gcuguccggc     1680

aucaacaaua uagcuuucuc aaacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7103
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7103
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7104
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7104
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cuccacaccu gugacccuga gcaaagacca gcuuucuggg     1680

aucaacaaua uugcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7105
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7105
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacucaaa      120

gcaaaugcaa uuaccacuau acucacagcu guaacuuuuu guuucgccuc aggacaaaac      180

aucacagaag aauuuuauca auccacaugc ucugccguau caaaaggcua ccuaucugcc      240

cuaagaacag guugguacac aucuguaaua acaaucgaau uauccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaaac aagaauuaga uaaauauaaa      360

aacgcaguaa cagaacuaca aaugcuaaug ugcucuacac ccgccacagg aucaggaucc      420

gcaaucgcuu cuggaguagc cguuugcaaa guauuacacc uagaaggaga aguaaauaaa      480

auaaaauccg cacuacuauc aacuaauaaa gcaguaguau cacuuucuaa ugguguauca      540

guauuaacau ucaaaguccu cgaccuaaaa aauuacaucg acaaacaacu auuacccauc      600

cuuaauaaac aaucaugcuc cauaucaaac auagaaacug ucauggaauu ucaacaaaaa      660

aacaauagac uucuagaaau cacaagagaa uuuucuguaa augcaggagu aacuacacca      720

guaucaacau auauguuaac caacuccgaa cuacuaucac ucauaaacga caugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguucaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguu uuagcauacg ucguacaacu uccccuauac      900

ggaguaauag acaccccuug cuggaaacuc cacaccucac cacuaugcac uacaaacaca      960

aaagaagguu ccaacaucug cuuaacaaga accgaucgag gaugguacug cgacaacgcu     1020

gguuccguau cuuucuuccc acaagcagaa acaugcaaag uaugcuccaa uagaguauuc     1080

ugcgacacca ugaacucacu aacucuacca uccgaaguaa accuaugcaa cgucgacaua     1140

uuuaauccaa aauaugacug caaaauaaug acuucaaaaa cagacguauc cucaucagua     1200

auaacauccu uaggagcaau aguaucaugu uacggcaaga caaaauguac agccucaaac     1260

aaaaacaaag guaucauuaa aaccuucucc aacggcugcg acuacguauc aaauaaaggu     1320

gucgauacag uaucaguagg aaacacacuc uauuacguua auaaacaaga aggaaaguca     1380

uuauacguaa aaggagaacc aauaaucaau uucuacgauc cccuagucuu ucccucagau     1440

gaauuugacg caagcaucuc ucaagucaac gaaaaaauaa accaaucccu agccuucaua     1500

agaaaaucag augaacuacu ucauaacguc aacgccggaa aaucaacaac caacauaaug     1560

aucacuacaa ucauaauugu aauuauagua auacuacuau cgcuaauugc cguuggacua     1620

cuacuauauu guaaagcaag aucaacaccc guuacucuau ccaaagauca auuaucagga     1680

aucaacaaca uagccuucuc aaauuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7106
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7106
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuuaaa      120

gccaacgcaa uaaccacaau ccucaccgcc gucacauucu gcuucgccuc gggacaaaac      180

auaaccgaag aauuuuacca gucuaccugc uccgccgucu ccaaggguua ccucuccgcg      240

cuccgcaccg ggugguacac cagcguuauc accaucgaac uaucuaacau aaaagaaaac      300

aagugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaag      360

aaugccguca ccgaacuaca aaugcucaug ugcuccaccc ccgccaccgg auccggcucc      420

gccauugccu ccggcgucgc cguaugcaaa guccuucacu uggaaggaga aguuaacaaa      480

auaaaaagcg cccuccuguc gaccaacaaa gcggugguca gccucuccaa cggcgucucu      540

guccucaccu ucaaaguccu cgaccucaag aacuacauag auaaacaacu acuccccauc      600

cuaaacaaac agucaugcag cauauccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaccgcc uccuugaaau cacccgcgag uucucuguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucguca acaaucauac      840

ucaaucaugu gcaucauuaa agaagaaguc cucgcauacg ucguccaacu cccccucuau      900

ggggucaucg acaccccaug cuggaaacuc cacaccucuc cccuaugcac caccaacacc      960

aaagaaggcu ccaacaucug ccuaacccga accgaccgcg gaugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgaa acauguaaag ucugcuccaa ccguguguuc     1080

ugcgacacca ugaacucacu aacccucccc uccgaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaauaaug accagcaaaa cagacguauc cucuagcguc     1200

auuaccagcc uaggugcaau cguguccugc uacggcaaaa caaaaugcac cgccuccaac     1260

aaaaauaaag gaaucauaaa aaccuucucc aacggcugcg acuacgucag caacaaagga     1320

gucgacaccg ucuccguagg aaauacucua uacuauguca acaaacaaga ggguaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccucugac     1440

gaguucgacg ccagcauauc acaaguaaac gaaaagauca accaaucccu cgcauucauu     1500

cgcaaauccg acgaacuccu acacaacguc aacgccggaa aauccaccac caacaucaug     1560

aucacuacua ucauuaucgu caucaucguc auccuccucu cccucaucgc agucggccuu     1620

cuacucuacu gcaaggcacg cucuacaccc guaacccugu cuaaagacca acucuccggc     1680

aucaacaaca ucgcuuucuc caacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7107
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7107
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7108
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7108
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cuccaccccg gugacccuga gcaaggacca gcuguccggg     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7109
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7109
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7110
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7110
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gucuacaccg gugaccuuga gcaaagacca gcuguccggc     1680

aucaacaaua uagcuuucuc aaacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7111
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7111
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7112
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7112
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cuccacaccu gugacccuga gcaaagacca gcuuucuggg     1680

aucaacaaua uugcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7113
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7113
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacucaaa      120

gcaaaugcaa uuaccacuau acucacagcu guaacuuuuu guuucgccuc aggacaaaac      180

aucacagaag aauuuuauca auccacaugc ucugccguau caaaaggcua ccuaucugcc      240

cuaagaacag guugguacac aucuguaaua acaaucgaau uauccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaaac aagaauuaga uaaauauaaa      360

aacgcaguaa cagaacuaca aaugcuaaug ugcucuacac ccgccacagg aucaggaucc      420

gcaaucgcuu cuggaguagc cguuugcaaa guauuacacc uagaaggaga aguaaauaaa      480

auaaaauccg cacuacuauc aacuaauaaa gcaguaguau cacuuucuaa ugguguauca      540

guauuaacau ucaaaguccu cgaccuaaaa aauuacaucg acaaacaacu auuacccauc      600

cuuaauaaac aaucaugcuc cauaucaaac auagaaacug ucauggaauu ucaacaaaaa      660

aacaauagac uucuagaaau cacaagagaa uuuucuguaa augcaggagu aacuacacca      720

guaucaacau auauguuaac caacuccgaa cuacuaucac ucauaaacga caugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguucaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguu uuagcauacg ucguacaacu uccccuauac      900

ggaguaauag acaccccuug cuggaaacuc cacaccucac cacuaugcac uacaaacaca      960

aaagaagguu ccaacaucug cuuaacaaga accgaucgag gaugguacug cgacaacgcu     1020

gguuccguau cuuucuuccc acaagcagaa acaugcaaag uaugcuccaa uagaguauuc     1080

ugcgacacca ugaacucacu aacucuacca uccgaaguaa accuaugcaa cgucgacaua     1140

uuuaauccaa aauaugacug caaaauaaug acuucaaaaa cagacguauc cucaucagua     1200

auaacauccu uaggagcaau aguaucaugu uacggcaaga caaaauguac agccucaaac     1260

aaaaacaaag guaucauuaa aaccuucucc aacggcugcg acuacguauc aaauaaaggu     1320

gucgauacag uaucaguagg aaacacacuc uauuacguua auaaacaaga aggaaaguca     1380

uuauacguaa aaggagaacc aauaaucaau uucuacgauc cccuagucuu ucccucagau     1440

gaauuugacg caagcaucuc ucaagucaac gaaaaaauaa accaaucccu agccuucaua     1500

agaaaaucag augaacuacu ucauaacguc aacgccggaa aaucaacaac caacauaaug     1560

aucacuacaa ucauaauugu aauuauagua auacuacuau cgcuaauugc cguuggacua     1620

cuacuauauu guaaagcaag aucaacaccc guuacucuau ccaaagauca auuaucagga     1680

aucaacaaca uagccuucuc aaauuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7114
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7114
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuuaaa      120

gccaacgcaa uaaccacaau ccucaccgcc gucacauucu gcuucgccuc gggacaaaac      180

auaaccgaag aauuuuacca gucuaccugc uccgccgucu ccaaggguua ccucuccgcg      240

cuccgcaccg ggugguacac cagcguuauc accaucgaac uaucuaacau aaaagaaaac      300

aagugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaag      360

aaugccguca ccgaacuaca aaugcucaug ugcuccaccc ccgccaccgg auccggcucc      420

gccauugccu ccggcgucgc cguaugcaaa guccuucacu uggaaggaga aguuaacaaa      480

auaaaaagcg cccuccuguc gaccaacaaa gcggugguca gccucuccaa cggcgucucu      540

guccucaccu ucaaaguccu cgaccucaag aacuacauag auaaacaacu acuccccauc      600

cuaaacaaac agucaugcag cauauccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaccgcc uccuugaaau cacccgcgag uucucuguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucguca acaaucauac      840

ucaaucaugu gcaucauuaa agaagaaguc cucgcauacg ucguccaacu cccccucuau      900

ggggucaucg acaccccaug cuggaaacuc cacaccucuc cccuaugcac caccaacacc      960

aaagaaggcu ccaacaucug ccuaacccga accgaccgcg gaugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgaa acauguaaag ucugcuccaa ccguguguuc     1080

ugcgacacca ugaacucacu aacccucccc uccgaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaauaaug accagcaaaa cagacguauc cucuagcguc     1200

auuaccagcc uaggugcaau cguguccugc uacggcaaaa caaaaugcac cgccuccaac     1260

aaaaauaaag gaaucauaaa aaccuucucc aacggcugcg acuacgucag caacaaagga     1320

gucgacaccg ucuccguagg aaauacucua uacuauguca acaaacaaga ggguaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccucugac     1440

gaguucgacg ccagcauauc acaaguaaac gaaaagauca accaaucccu cgcauucauu     1500

cgcaaauccg acgaacuccu acacaacguc aacgccggaa aauccaccac caacaucaug     1560

aucacuacua ucauuaucgu caucaucguc auccuccucu cccucaucgc agucggccuu     1620

cuacucuacu gcaaggcacg cucuacaccc guaacccugu cuaaagacca acucuccggc     1680

aucaacaaca ucgcuuucuc caacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7115
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7115
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7116
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7116
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cuccaccccg gugacccuga gcaaggacca gcuguccggg     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7117
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7117
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7118
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7118
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gucuacaccg gugaccuuga gcaaagacca gcuguccggc     1680

aucaacaaua uagcuuucuc aaacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7119
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7119
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7120
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7120
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cuccacaccu gugacccuga gcaaagacca gcuuucuggg     1680

aucaacaaua uugcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7121
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7121
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu cauacucaaa      120

gcaaaugcaa uuaccacuau acucacagcu guaacuuuuu guuucgccuc aggacaaaac      180

aucacagaag aauuuuauca auccacaugc ucugccguau caaaaggcua ccuaucugcc      240

cuaagaacag guugguacac aucuguaaua acaaucgaau uauccaacau caaagaaaac      300

aaaugcaacg gcacagacgc aaaagucaaa cucaucaaac aagaauuaga uaaauauaaa      360

aacgcaguaa cagaacuaca aaugcuaaug ugcucuacac ccgccacagg aucaggaucc      420

gcaaucgcuu cuggaguagc cguuugcaaa guauuacacc uagaaggaga aguaaauaaa      480

auaaaauccg cacuacuauc aacuaauaaa gcaguaguau cacuuucuaa ugguguauca      540

guauuaacau ucaaaguccu cgaccuaaaa aauuacaucg acaaacaacu auuacccauc      600

cuuaauaaac aaucaugcuc cauaucaaac auagaaacug ucauggaauu ucaacaaaaa      660

aacaauagac uucuagaaau cacaagagaa uuuucuguaa augcaggagu aacuacacca      720

guaucaacau auauguuaac caacuccgaa cuacuaucac ucauaaacga caugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguucaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaaguu uuagcauacg ucguacaacu uccccuauac      900

ggaguaauag acaccccuug cuggaaacuc cacaccucac cacuaugcac uacaaacaca      960

aaagaagguu ccaacaucug cuuaacaaga accgaucgag gaugguacug cgacaacgcu     1020

gguuccguau cuuucuuccc acaagcagaa acaugcaaag uaugcuccaa uagaguauuc     1080

ugcgacacca ugaacucacu aacucuacca uccgaaguaa accuaugcaa cgucgacaua     1140

uuuaauccaa aauaugacug caaaauaaug acuucaaaaa cagacguauc cucaucagua     1200

auaacauccu uaggagcaau aguaucaugu uacggcaaga caaaauguac agccucaaac     1260

aaaaacaaag guaucauuaa aaccuucucc aacggcugcg acuacguauc aaauaaaggu     1320

gucgauacag uaucaguagg aaacacacuc uauuacguua auaaacaaga aggaaaguca     1380

uuauacguaa aaggagaacc aauaaucaau uucuacgauc cccuagucuu ucccucagau     1440

gaauuugacg caagcaucuc ucaagucaac gaaaaaauaa accaaucccu agccuucaua     1500

agaaaaucag augaacuacu ucauaacguc aacgccggaa aaucaacaac caacauaaug     1560

aucacuacaa ucauaauugu aauuauagua auacuacuau cgcuaauugc cguuggacua     1620

cuacuauauu guaaagcaag aucaacaccc guuacucuau ccaaagauca auuaucagga     1680

aucaacaaca uagccuucuc aaauuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7122
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7122
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauacuuaaa      120

gccaacgcaa uaaccacaau ccucaccgcc gucacauucu gcuucgccuc gggacaaaac      180

auaaccgaag aauuuuacca gucuaccugc uccgccgucu ccaaggguua ccucuccgcg      240

cuccgcaccg ggugguacac cagcguuauc accaucgaac uaucuaacau aaaagaaaac      300

aagugcaacg gaaccgacgc aaaagucaaa cucaucaaac aagaacuaga caaauacaag      360

aaugccguca ccgaacuaca aaugcucaug ugcuccaccc ccgccaccgg auccggcucc      420

gccauugccu ccggcgucgc cguaugcaaa guccuucacu uggaaggaga aguuaacaaa      480

auaaaaagcg cccuccuguc gaccaacaaa gcggugguca gccucuccaa cggcgucucu      540

guccucaccu ucaaaguccu cgaccucaag aacuacauag auaaacaacu acuccccauc      600

cuaaacaaac agucaugcag cauauccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaccgcc uccuugaaau cacccgcgag uucucuguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac aaacuccgaa cuccucagcc ucaucaacga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaaa ucguucguca acaaucauac      840

ucaaucaugu gcaucauuaa agaagaaguc cucgcauacg ucguccaacu cccccucuau      900

ggggucaucg acaccccaug cuggaaacuc cacaccucuc cccuaugcac caccaacacc      960

aaagaaggcu ccaacaucug ccuaacccga accgaccgcg gaugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgaa acauguaaag ucugcuccaa ccguguguuc     1080

ugcgacacca ugaacucacu aacccucccc uccgaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaauaaug accagcaaaa cagacguauc cucuagcguc     1200

auuaccagcc uaggugcaau cguguccugc uacggcaaaa caaaaugcac cgccuccaac     1260

aaaaauaaag gaaucauaaa aaccuucucc aacggcugcg acuacgucag caacaaagga     1320

gucgacaccg ucuccguagg aaauacucua uacuauguca acaaacaaga ggguaaaucc     1380

cucuacguca aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccucugac     1440

gaguucgacg ccagcauauc acaaguaaac gaaaagauca accaaucccu cgcauucauu     1500

cgcaaauccg acgaacuccu acacaacguc aacgccggaa aauccaccac caacaucaug     1560

aucacuacua ucauuaucgu caucaucguc auccuccucu cccucaucgc agucggccuu     1620

cuacucuacu gcaaggcacg cucuacaccc guaacccugu cuaaagacca acucuccggc     1680

aucaacaaca ucgcuuucuc caacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7123
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7123
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7124
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7124
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcucca ccccggugac ccugagcaag     1740

gaccagcugu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7125
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7125
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7126
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7126
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggucua caccggugac cuugagcaaa     1740

gaccagcugu ccggcaucaa caauauagcu uucucaaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7127
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7127
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7128
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7128
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcucca caccugugac ccugagcaaa     1740

gaccagcuuu cugggaucaa caauauugcg uucuccaacu gaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7129
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7129
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac ucaaagcaaa ugcaauuacc acuauacuca cagcuguaac uuuuuguuuc      240

gccucaggac aaaacaucac agaagaauuu uaucaaucca caugcucugc cguaucaaaa      300

ggcuaccuau cugcccuaag aacagguugg uacacaucug uaauaacaau cgaauuaucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caaacaagaa      420

uuagauaaau auaaaaacgc aguaacagaa cuacaaaugc uaaugugcuc uacacccgcc      480

acaggaucag gauccgcaau cgcuucugga guagccguuu gcaaaguauu acaccuagaa      540

ggagaaguaa auaaaauaaa auccgcacua cuaucaacua auaaagcagu aguaucacuu      600

ucuaauggug uaucaguauu aacauucaaa guccucgacc uaaaaaauua caucgacaaa      660

caacuauuac ccauccuuaa uaaacaauca ugcuccauau caaacauaga aacugucaug      720

gaauuucaac aaaaaaacaa uagacuucua gaaaucacaa gagaauuuuc uguaaaugca      780

ggaguaacua caccaguauc aacauauaug uuaaccaacu ccgaacuacu aucacucaua      840

aacgacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu ucaaauagua      900

agacaacaau cauacucaau caugugcaua auaaaagaag aaguuuuagc auacgucgua      960

caacuucccc uauacggagu aauagacacc ccuugcugga aacuccacac cucaccacua     1020

ugcacuacaa acacaaaaga agguuccaac aucugcuuaa caagaaccga ucgaggaugg     1080

uacugcgaca acgcugguuc cguaucuuuc uucccacaag cagaaacaug caaaguaugc     1140

uccaauagag uauucugcga caccaugaac ucacuaacuc uaccauccga aguaaaccua     1200

ugcaacgucg acauauuuaa uccaaaauau gacugcaaaa uaaugacuuc aaaaacagac     1260

guauccucau caguaauaac auccuuagga gcaauaguau cauguuacgg caagacaaaa     1320

uguacagccu caaacaaaaa caaagguauc auuaaaaccu ucuccaacgg cugcgacuac     1380

guaucaaaua aaggugucga uacaguauca guaggaaaca cacucuauua cguuaauaaa     1440

caagaaggaa agucauuaua cguaaaagga gaaccaauaa ucaauuucua cgauccccua     1500

gucuuucccu cagaugaauu ugacgcaagc aucucucaag ucaacgaaaa aauaaaccaa     1560

ucccuagccu ucauaagaaa aucagaugaa cuacuucaua acgucaacgc cggaaaauca     1620

acaaccaaca uaaugaucac uacaaucaua auuguaauua uaguaauacu acuaucgcua     1680

auugccguug gacuacuacu auauuguaaa gcaagaucaa cacccguuac ucuauccaaa     1740

gaucaauuau caggaaucaa caacauagcc uucucaaauu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7130
<211>  2045
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7130
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uuaaagccaa cgcaauaacc acaauccuca ccgccgucac auucugcuuc      240

gccucgggac aaaacauaac cgaagaauuu uaccagucua ccugcuccgc cgucuccaag      300

gguuaccucu ccgcgcuccg caccgggugg uacaccagcg uuaucaccau cgaacuaucu      360

aacauaaaag aaaacaagug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaagaaugc cgucaccgaa cuacaaaugc ucaugugcuc cacccccgcc      480

accggauccg gcuccgccau ugccuccggc gucgccguau gcaaaguccu ucacuuggaa      540

ggagaaguua acaaaauaaa aagcgcccuc cugucgacca acaaagcggu ggucagccuc      600

uccaacggcg ucucuguccu caccuucaaa guccucgacc ucaagaacua cauagauaaa      660

caacuacucc ccauccuaaa caaacaguca ugcagcauau ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ccgccuccuu gaaaucaccc gcgaguucuc ugucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucacaaacu ccgaacuccu cagccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgucaacaau cauacucaau caugugcauc auuaaagaag aaguccucgc auacgucguc      960

caacuccccc ucuauggggu caucgacacc ccaugcugga aacuccacac cucuccccua     1020

ugcaccacca acaccaaaga aggcuccaac aucugccuaa cccgaaccga ccgcggaugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgaaacaug uaaagucugc     1140

uccaaccgug uguucugcga caccaugaac ucacuaaccc uccccuccga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa uaaugaccag caaaacagac     1260

guauccucua gcgucauuac cagccuaggu gcaaucgugu ccugcuacgg caaaacaaaa     1320

ugcaccgccu ccaacaaaaa uaaaggaauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucagcaaca aaggagucga caccgucucc guaggaaaua cucuauacua ugucaacaaa     1440

caagagggua aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu cugacgaguu cgacgccagc auaucacaag uaaacgaaaa gaucaaccaa     1560

ucccucgcau ucauucgcaa auccgacgaa cuccuacaca acgucaacgc cggaaaaucc     1620

accaccaaca ucaugaucac uacuaucauu aucgucauca ucgucauccu ccucucccuc     1680

aucgcagucg gccuucuacu cuacugcaag gcacgcucua cacccguaac ccugucuaaa     1740

gaccaacucu ccggcaucaa caacaucgcu uucuccaacu aaggacuagu aauaaggaaa     1800

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1860

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     2040

gaauu                                                                 2045


<210>  7131
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7131
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7132
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7132
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcucca ccccggugac ccugagcaag     1740

gaccagcugu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7133
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7133
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7134
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7134
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggucua caccggugac cuugagcaaa     1740

gaccagcugu ccggcaucaa caauauagcu uucucaaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7135
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7135
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7136
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7136
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcucca caccugugac ccugagcaaa     1740

gaccagcuuu cugggaucaa caauauugcg uucuccaacu gaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7137
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7137
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac ucaaagcaaa ugcaauuacc acuauacuca cagcuguaac uuuuuguuuc      240

gccucaggac aaaacaucac agaagaauuu uaucaaucca caugcucugc cguaucaaaa      300

ggcuaccuau cugcccuaag aacagguugg uacacaucug uaauaacaau cgaauuaucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caaacaagaa      420

uuagauaaau auaaaaacgc aguaacagaa cuacaaaugc uaaugugcuc uacacccgcc      480

acaggaucag gauccgcaau cgcuucugga guagccguuu gcaaaguauu acaccuagaa      540

ggagaaguaa auaaaauaaa auccgcacua cuaucaacua auaaagcagu aguaucacuu      600

ucuaauggug uaucaguauu aacauucaaa guccucgacc uaaaaaauua caucgacaaa      660

caacuauuac ccauccuuaa uaaacaauca ugcuccauau caaacauaga aacugucaug      720

gaauuucaac aaaaaaacaa uagacuucua gaaaucacaa gagaauuuuc uguaaaugca      780

ggaguaacua caccaguauc aacauauaug uuaaccaacu ccgaacuacu aucacucaua      840

aacgacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu ucaaauagua      900

agacaacaau cauacucaau caugugcaua auaaaagaag aaguuuuagc auacgucgua      960

caacuucccc uauacggagu aauagacacc ccuugcugga aacuccacac cucaccacua     1020

ugcacuacaa acacaaaaga agguuccaac aucugcuuaa caagaaccga ucgaggaugg     1080

uacugcgaca acgcugguuc cguaucuuuc uucccacaag cagaaacaug caaaguaugc     1140

uccaauagag uauucugcga caccaugaac ucacuaacuc uaccauccga aguaaaccua     1200

ugcaacgucg acauauuuaa uccaaaauau gacugcaaaa uaaugacuuc aaaaacagac     1260

guauccucau caguaauaac auccuuagga gcaauaguau cauguuacgg caagacaaaa     1320

uguacagccu caaacaaaaa caaagguauc auuaaaaccu ucuccaacgg cugcgacuac     1380

guaucaaaua aaggugucga uacaguauca guaggaaaca cacucuauua cguuaauaaa     1440

caagaaggaa agucauuaua cguaaaagga gaaccaauaa ucaauuucua cgauccccua     1500

gucuuucccu cagaugaauu ugacgcaagc aucucucaag ucaacgaaaa aauaaaccaa     1560

ucccuagccu ucauaagaaa aucagaugaa cuacuucaua acgucaacgc cggaaaauca     1620

acaaccaaca uaaugaucac uacaaucaua auuguaauua uaguaauacu acuaucgcua     1680

auugccguug gacuacuacu auauuguaaa gcaagaucaa cacccguuac ucuauccaaa     1740

gaucaauuau caggaaucaa caacauagcc uucucaaauu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7138
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7138
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uuaaagccaa cgcaauaacc acaauccuca ccgccgucac auucugcuuc      240

gccucgggac aaaacauaac cgaagaauuu uaccagucua ccugcuccgc cgucuccaag      300

gguuaccucu ccgcgcuccg caccgggugg uacaccagcg uuaucaccau cgaacuaucu      360

aacauaaaag aaaacaagug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaagaaugc cgucaccgaa cuacaaaugc ucaugugcuc cacccccgcc      480

accggauccg gcuccgccau ugccuccggc gucgccguau gcaaaguccu ucacuuggaa      540

ggagaaguua acaaaauaaa aagcgcccuc cugucgacca acaaagcggu ggucagccuc      600

uccaacggcg ucucuguccu caccuucaaa guccucgacc ucaagaacua cauagauaaa      660

caacuacucc ccauccuaaa caaacaguca ugcagcauau ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ccgccuccuu gaaaucaccc gcgaguucuc ugucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucacaaacu ccgaacuccu cagccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgucaacaau cauacucaau caugugcauc auuaaagaag aaguccucgc auacgucguc      960

caacuccccc ucuauggggu caucgacacc ccaugcugga aacuccacac cucuccccua     1020

ugcaccacca acaccaaaga aggcuccaac aucugccuaa cccgaaccga ccgcggaugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgaaacaug uaaagucugc     1140

uccaaccgug uguucugcga caccaugaac ucacuaaccc uccccuccga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa uaaugaccag caaaacagac     1260

guauccucua gcgucauuac cagccuaggu gcaaucgugu ccugcuacgg caaaacaaaa     1320

ugcaccgccu ccaacaaaaa uaaaggaauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucagcaaca aaggagucga caccgucucc guaggaaaua cucuauacua ugucaacaaa     1440

caagagggua aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu cugacgaguu cgacgccagc auaucacaag uaaacgaaaa gaucaaccaa     1560

ucccucgcau ucauucgcaa auccgacgaa cuccuacaca acgucaacgc cggaaaaucc     1620

accaccaaca ucaugaucac uacuaucauu aucgucauca ucgucauccu ccucucccuc     1680

aucgcagucg gccuucuacu cuacugcaag gcacgcucua cacccguaac ccugucuaaa     1740

gaccaacucu ccggcaucaa caacaucgcu uucuccaacu aaggacuagu acuggcugca     1800

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1860

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1920

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2040

cuuuucagag ccaccagaau u                                               2061


<210>  7139
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7139
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggagca cgcccgucac ccuguccaag     1740

gaccagcuga gcggcaucaa caacaucgcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7140
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7140
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcucca ccccggugac ccugagcaag     1740

gaccagcugu ccgggaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7141
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7141
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcucca cccccgucac ccucuccaag     1740

gaccagcucu ccggcaucaa caacaucgcc uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7142
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7142
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggucua caccggugac cuugagcaaa     1740

gaccagcugu ccggcaucaa caauauagcu uucucaaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7143
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7143
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaagca cccccgugac ccugagcaag     1740

gaccagcuga gcggcaucaa caacaucgcc uucagcaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7144
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7144
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcucca caccugugac ccugagcaaa     1740

gaccagcuuu cugggaucaa caauauugcg uucuccaacu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7145
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7145
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacucauac ucaaagcaaa ugcaauuacc acuauacuca cagcuguaac uuuuuguuuc      240

gccucaggac aaaacaucac agaagaauuu uaucaaucca caugcucugc cguaucaaaa      300

ggcuaccuau cugcccuaag aacagguugg uacacaucug uaauaacaau cgaauuaucc      360

aacaucaaag aaaacaaaug caacggcaca gacgcaaaag ucaaacucau caaacaagaa      420

uuagauaaau auaaaaacgc aguaacagaa cuacaaaugc uaaugugcuc uacacccgcc      480

acaggaucag gauccgcaau cgcuucugga guagccguuu gcaaaguauu acaccuagaa      540

ggagaaguaa auaaaauaaa auccgcacua cuaucaacua auaaagcagu aguaucacuu      600

ucuaauggug uaucaguauu aacauucaaa guccucgacc uaaaaaauua caucgacaaa      660

caacuauuac ccauccuuaa uaaacaauca ugcuccauau caaacauaga aacugucaug      720

gaauuucaac aaaaaaacaa uagacuucua gaaaucacaa gagaauuuuc uguaaaugca      780

ggaguaacua caccaguauc aacauauaug uuaaccaacu ccgaacuacu aucacucaua      840

aacgacaugc caauaacaaa cgaccaaaaa aaacuaaugu caaauaacgu ucaaauagua      900

agacaacaau cauacucaau caugugcaua auaaaagaag aaguuuuagc auacgucgua      960

caacuucccc uauacggagu aauagacacc ccuugcugga aacuccacac cucaccacua     1020

ugcacuacaa acacaaaaga agguuccaac aucugcuuaa caagaaccga ucgaggaugg     1080

uacugcgaca acgcugguuc cguaucuuuc uucccacaag cagaaacaug caaaguaugc     1140

uccaauagag uauucugcga caccaugaac ucacuaacuc uaccauccga aguaaaccua     1200

ugcaacgucg acauauuuaa uccaaaauau gacugcaaaa uaaugacuuc aaaaacagac     1260

guauccucau caguaauaac auccuuagga gcaauaguau cauguuacgg caagacaaaa     1320

uguacagccu caaacaaaaa caaagguauc auuaaaaccu ucuccaacgg cugcgacuac     1380

guaucaaaua aaggugucga uacaguauca guaggaaaca cacucuauua cguuaauaaa     1440

caagaaggaa agucauuaua cguaaaagga gaaccaauaa ucaauuucua cgauccccua     1500

gucuuucccu cagaugaauu ugacgcaagc aucucucaag ucaacgaaaa aauaaaccaa     1560

ucccuagccu ucauaagaaa aucagaugaa cuacuucaua acgucaacgc cggaaaauca     1620

acaaccaaca uaaugaucac uacaaucaua auuguaauua uaguaauacu acuaucgcua     1680

auugccguug gacuacuacu auauuguaaa gcaagaucaa cacccguuac ucuauccaaa     1740

gaucaauuau caggaaucaa caacauagcc uucucaaauu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7146
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7146
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauac uuaaagccaa cgcaauaacc acaauccuca ccgccgucac auucugcuuc      240

gccucgggac aaaacauaac cgaagaauuu uaccagucua ccugcuccgc cgucuccaag      300

gguuaccucu ccgcgcuccg caccgggugg uacaccagcg uuaucaccau cgaacuaucu      360

aacauaaaag aaaacaagug caacggaacc gacgcaaaag ucaaacucau caaacaagaa      420

cuagacaaau acaagaaugc cgucaccgaa cuacaaaugc ucaugugcuc cacccccgcc      480

accggauccg gcuccgccau ugccuccggc gucgccguau gcaaaguccu ucacuuggaa      540

ggagaaguua acaaaauaaa aagcgcccuc cugucgacca acaaagcggu ggucagccuc      600

uccaacggcg ucucuguccu caccuucaaa guccucgacc ucaagaacua cauagauaaa      660

caacuacucc ccauccuaaa caaacaguca ugcagcauau ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ccgccuccuu gaaaucaccc gcgaguucuc ugucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucacaaacu ccgaacuccu cagccucauc      840

aacgacaugc caaucaccaa cgaccaaaag aaacucaugu ccaacaacgu acaaaucguu      900

cgucaacaau cauacucaau caugugcauc auuaaagaag aaguccucgc auacgucguc      960

caacuccccc ucuauggggu caucgacacc ccaugcugga aacuccacac cucuccccua     1020

ugcaccacca acaccaaaga aggcuccaac aucugccuaa cccgaaccga ccgcggaugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgaaacaug uaaagucugc     1140

uccaaccgug uguucugcga caccaugaac ucacuaaccc uccccuccga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa uaaugaccag caaaacagac     1260

guauccucua gcgucauuac cagccuaggu gcaaucgugu ccugcuacgg caaaacaaaa     1320

ugcaccgccu ccaacaaaaa uaaaggaauc auaaaaaccu ucuccaacgg cugcgacuac     1380

gucagcaaca aaggagucga caccgucucc guaggaaaua cucuauacua ugucaacaaa     1440

caagagggua aaucccucua cgucaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu cugacgaguu cgacgccagc auaucacaag uaaacgaaaa gaucaaccaa     1560

ucccucgcau ucauucgcaa auccgacgaa cuccuacaca acgucaacgc cggaaaaucc     1620

accaccaaca ucaugaucac uacuaucauu aucgucauca ucgucauccu ccucucccuc     1680

aucgcagucg gccuucuacu cuacugcaag gcacgcucua cacccguaac ccugucuaaa     1740

gaccaacucu ccggcaucaa caacaucgcu uucuccaacu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7147
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7147
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1620

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7148
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7148
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      480

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1320

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu ccaccccggu gacccugagc     1620

aaggaccagc uguccgggau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7149
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7149
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1620

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7150
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7150
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      420

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      480

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      540

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      720

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      780

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua      840

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca      900

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc      960

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1020

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1080

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1140

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1200

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1260

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1320

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1380

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1440

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1500

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1560

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu cuacaccggu gaccuugagc     1620

aaagaccagc uguccggcau caacaauaua gcuuucucaa acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7151
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7151
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1620

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7152
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7152
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      420

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      480

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      540

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      720

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      780

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug      840

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu      900

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga      960

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1020

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1080

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1140

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1260

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1380

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1440

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1500

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1560

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu ccacaccugu gacccugagc     1620

aaagaccagc uuucugggau caacaauauu gcguucucca acugaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7153
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7153
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaauuacuca uacucaaagc aaaugcaauu accacuauac ucacagcugu aacuuuuugu      120

uucgccucag gacaaaacau cacagaagaa uuuuaucaau ccacaugcuc ugccguauca      180

aaaggcuacc uaucugcccu aagaacaggu ugguacacau cuguaauaac aaucgaauua      240

uccaacauca aagaaaacaa augcaacggc acagacgcaa aagucaaacu caucaaacaa      300

gaauuagaua aauauaaaaa cgcaguaaca gaacuacaaa ugcuaaugug cucuacaccc      360

gccacaggau caggauccgc aaucgcuucu ggaguagccg uuugcaaagu auuacaccua      420

gaaggagaag uaaauaaaau aaaauccgca cuacuaucaa cuaauaaagc aguaguauca      480

cuuucuaaug guguaucagu auuaacauuc aaaguccucg accuaaaaaa uuacaucgac      540

aaacaacuau uacccauccu uaauaaacaa ucaugcucca uaucaaacau agaaacuguc      600

auggaauuuc aacaaaaaaa caauagacuu cuagaaauca caagagaauu uucuguaaau      660

gcaggaguaa cuacaccagu aucaacauau auguuaacca acuccgaacu acuaucacuc      720

auaaacgaca ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguucaaaua      780

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguuuu agcauacguc      840

guacaacuuc cccuauacgg aguaauagac accccuugcu ggaaacucca caccucacca      900

cuaugcacua caaacacaaa agaagguucc aacaucugcu uaacaagaac cgaucgagga      960

ugguacugcg acaacgcugg uuccguaucu uucuucccac aagcagaaac augcaaagua     1020

ugcuccaaua gaguauucug cgacaccaug aacucacuaa cucuaccauc cgaaguaaac     1080

cuaugcaacg ucgacauauu uaauccaaaa uaugacugca aaauaaugac uucaaaaaca     1140

gacguauccu caucaguaau aacauccuua ggagcaauag uaucauguua cggcaagaca     1200

aaauguacag ccucaaacaa aaacaaaggu aucauuaaaa ccuucuccaa cggcugcgac     1260

uacguaucaa auaaaggugu cgauacagua ucaguaggaa acacacucua uuacguuaau     1320

aaacaagaag gaaagucauu auacguaaaa ggagaaccaa uaaucaauuu cuacgauccc     1380

cuagucuuuc ccucagauga auuugacgca agcaucucuc aagucaacga aaaaauaaac     1440

caaucccuag ccuucauaag aaaaucagau gaacuacuuc auaacgucaa cgccggaaaa     1500

ucaacaacca acauaaugau cacuacaauc auaauuguaa uuauaguaau acuacuaucg     1560

cuaauugccg uuggacuacu acuauauugu aaagcaagau caacacccgu uacucuaucc     1620

aaagaucaau uaucaggaau caacaacaua gccuucucaa auuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7154
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7154
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuca uacuuaaagc caacgcaaua accacaaucc ucaccgccgu cacauucugc      120

uucgccucgg gacaaaacau aaccgaagaa uuuuaccagu cuaccugcuc cgccgucucc      180

aaggguuacc ucuccgcgcu ccgcaccggg ugguacacca gcguuaucac caucgaacua      240

ucuaacauaa aagaaaacaa gugcaacgga accgacgcaa aagucaaacu caucaaacaa      300

gaacuagaca aauacaagaa ugccgucacc gaacuacaaa ugcucaugug cuccaccccc      360

gccaccggau ccggcuccgc cauugccucc ggcgucgccg uaugcaaagu ccuucacuug      420

gaaggagaag uuaacaaaau aaaaagcgcc cuccugucga ccaacaaagc gguggucagc      480

cucuccaacg gcgucucugu ccucaccuuc aaaguccucg accucaagaa cuacauagau      540

aaacaacuac uccccauccu aaacaaacag ucaugcagca uauccaacau cgaaaccguc      600

auggaguucc aacagaaaaa caaccgccuc cuugaaauca cccgcgaguu cucugucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacaa acuccgaacu ccucagccuc      720

aucaacgaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacaaauc      780

guucgucaac aaucauacuc aaucaugugc aucauuaaag aagaaguccu cgcauacguc      840

guccaacucc cccucuaugg ggucaucgac accccaugcu ggaaacucca caccucuccc      900

cuaugcacca ccaacaccaa agaaggcucc aacaucugcc uaacccgaac cgaccgcgga      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgaaac auguaaaguc     1020

ugcuccaacc guguguucug cgacaccaug aacucacuaa cccuccccuc cgaagucaac     1080

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaauaaugac cagcaaaaca     1140

gacguauccu cuagcgucau uaccagccua ggugcaaucg uguccugcua cggcaaaaca     1200

aaaugcaccg ccuccaacaa aaauaaagga aucauaaaaa ccuucuccaa cggcugcgac     1260

uacgucagca acaaaggagu cgacaccguc uccguaggaa auacucuaua cuaugucaac     1320

aaacaagagg guaaaucccu cuacgucaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccucugacga guucgacgcc agcauaucac aaguaaacga aaagaucaac     1440

caaucccucg cauucauucg caaauccgac gaacuccuac acaacgucaa cgccggaaaa     1500

uccaccacca acaucaugau cacuacuauc auuaucguca ucaucgucau ccuccucucc     1560

cucaucgcag ucggccuucu acucuacugc aaggcacgcu cuacacccgu aacccugucu     1620

aaagaccaac ucuccggcau caacaacauc gcuuucucca acuaaggacu agugcaucac     1680

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1740

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1800

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7155
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7155
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag acggugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugugca     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc cuguccaagg     1620

accagcugag cggcaucaac aacaucgcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7156
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7156
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc acccccgcca      360

ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug caccuggagg      420

gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug gucucccuga      480

gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac aucgacaagc      540

agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag accgugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc gugaacgccg      660

gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac cggggguggu      960

acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag gucaaccucu     1080

gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg aagaccaagu     1200

gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg ugcgacuacg     1260

ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac gucaacaagc     1320

aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc gggaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug cucagccuga     1560

ucgccguggg ccugcuccug uacugcaagg cccgcuccac cccggugacc cugagcaagg     1620

accagcuguc cgggaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7157
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7157
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag accgucaugg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac gucaacaagc     1320

aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc cucuccaagg     1620

accagcucuc cggcaucaac aacaucgccu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7158
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7158
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu acacccgcca      360

ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug cacuuggagg      420

gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug gucucucuga      480

gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac auugauaaac      540

agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag accgugaugg      600

aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu gucaacgcgg      660

gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug agcuugauua      720

acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc caaauuguuc      780

gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca uauguagugc      840

aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca agcccacuuu      900

gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau cguggcuggu      960

acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu aagguuugcu     1020

caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag gucaaccugu     1080

guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc aaaacagacg     1140

uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu aagaccaaau     1200

gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg ugugauuaug     1260

ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau guuaacaaac     1320

aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau gacccucugg     1380

uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag auaaaccaaa     1440

guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg ggaaaaucaa     1500

caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua cugagucuaa     1560

uugccgucgg ccuccugcuu uacugcaagg cacggucuac accggugacc uugagcaaag     1620

accagcuguc cggcaucaac aauauagcuu ucucaaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7159
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7159
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag accgugaugg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugugca     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc cugagcaagg     1620

accagcugag cggcaucaac aacaucgccu ucagcaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7160
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7160
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc acccccgcca      360

cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug caccucgagg      420

gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc gugucccuga      480

gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac auugauaaac      540

agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag accgugaugg      600

aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc gugaacgccg      660

gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug ucucucauca      720

acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug caaauuguga      780

gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu uaugugguuc      840

agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg ucuccucugu      900

gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau cgcggauggu      960

acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu aaggugugca     1020

gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag gugaaucugu     1080

guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc aaaacagacg     1140

uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga aagacaaaau     1200

gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg ugugauuaug     1260

uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau guuaacaaac     1320

aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau gacccucugg     1380

ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag aucaaccaaa     1440

gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc ggaaaaagca     1500

caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc cugucucuua     1560

uugccguggg ccugcuccug uacugcaagg cucgcuccac accugugacc cugagcaaag     1620

accagcuuuc ugggaucaac aauauugcgu ucuccaacug aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7161
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7161
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaau       60

uacucauacu caaagcaaau gcaauuacca cuauacucac agcuguaacu uuuuguuucg      120

ccucaggaca aaacaucaca gaagaauuuu aucaauccac augcucugcc guaucaaaag      180

gcuaccuauc ugcccuaaga acagguuggu acacaucugu aauaacaauc gaauuaucca      240

acaucaaaga aaacaaaugc aacggcacag acgcaaaagu caaacucauc aaacaagaau      300

uagauaaaua uaaaaacgca guaacagaac uacaaaugcu aaugugcucu acacccgcca      360

caggaucagg auccgcaauc gcuucuggag uagccguuug caaaguauua caccuagaag      420

gagaaguaaa uaaaauaaaa uccgcacuac uaucaacuaa uaaagcagua guaucacuuu      480

cuaauggugu aucaguauua acauucaaag uccucgaccu aaaaaauuac aucgacaaac      540

aacuauuacc cauccuuaau aaacaaucau gcuccauauc aaacauagaa acugucaugg      600

aauuucaaca aaaaaacaau agacuucuag aaaucacaag agaauuuucu guaaaugcag      660

gaguaacuac accaguauca acauauaugu uaaccaacuc cgaacuacua ucacucauaa      720

acgacaugcc aauaacaaac gaccaaaaaa aacuaauguc aaauaacguu caaauaguaa      780

gacaacaauc auacucaauc augugcauaa uaaaagaaga aguuuuagca uacgucguac      840

aacuuccccu auacggagua auagacaccc cuugcuggaa acuccacacc ucaccacuau      900

gcacuacaaa cacaaaagaa gguuccaaca ucugcuuaac aagaaccgau cgaggauggu      960

acugcgacaa cgcugguucc guaucuuucu ucccacaagc agaaacaugc aaaguaugcu     1020

ccaauagagu auucugcgac accaugaacu cacuaacucu accauccgaa guaaaccuau     1080

gcaacgucga cauauuuaau ccaaaauaug acugcaaaau aaugacuuca aaaacagacg     1140

uauccucauc aguaauaaca uccuuaggag caauaguauc auguuacggc aagacaaaau     1200

guacagccuc aaacaaaaac aaagguauca uuaaaaccuu cuccaacggc ugcgacuacg     1260

uaucaaauaa aggugucgau acaguaucag uaggaaacac acucuauuac guuaauaaac     1320

aagaaggaaa gucauuauac guaaaaggag aaccaauaau caauuucuac gauccccuag     1380

ucuuucccuc agaugaauuu gacgcaagca ucucucaagu caacgaaaaa auaaaccaau     1440

cccuagccuu cauaagaaaa ucagaugaac uacuucauaa cgucaacgcc ggaaaaucaa     1500

caaccaacau aaugaucacu acaaucauaa uuguaauuau aguaauacua cuaucgcuaa     1560

uugccguugg acuacuacua uauuguaaag caagaucaac acccguuacu cuauccaaag     1620

aucaauuauc aggaaucaac aacauagccu ucucaaauua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7162
<211>  1990
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7162
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacucauacu uaaagccaac gcaauaacca caauccucac cgccgucaca uucugcuucg      120

ccucgggaca aaacauaacc gaagaauuuu accagucuac cugcuccgcc gucuccaagg      180

guuaccucuc cgcgcuccgc accggguggu acaccagcgu uaucaccauc gaacuaucua      240

acauaaaaga aaacaagugc aacggaaccg acgcaaaagu caaacucauc aaacaagaac      300

uagacaaaua caagaaugcc gucaccgaac uacaaaugcu caugugcucc acccccgcca      360

ccggauccgg cuccgccauu gccuccggcg ucgccguaug caaaguccuu cacuuggaag      420

gagaaguuaa caaaauaaaa agcgcccucc ugucgaccaa caaagcggug gucagccucu      480

ccaacggcgu cucuguccuc accuucaaag uccucgaccu caagaacuac auagauaaac      540

aacuacuccc cauccuaaac aaacagucau gcagcauauc caacaucgaa accgucaugg      600

aguuccaaca gaaaaacaac cgccuccuug aaaucacccg cgaguucucu gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucacaaacuc cgaacuccuc agccucauca      720

acgacaugcc aaucaccaac gaccaaaaga aacucauguc caacaacgua caaaucguuc      780

gucaacaauc auacucaauc augugcauca uuaaagaaga aguccucgca uacgucgucc      840

aacucccccu cuaugggguc aucgacaccc caugcuggaa acuccacacc ucuccccuau      900

gcaccaccaa caccaaagaa ggcuccaaca ucugccuaac ccgaaccgac cgcggauggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgaaacaugu aaagucugcu     1020

ccaaccgugu guucugcgac accaugaacu cacuaacccu ccccuccgaa gucaaccucu     1080

gcaacgucga caucuucaac ccgaaauacg acugcaaaau aaugaccagc aaaacagacg     1140

uauccucuag cgucauuacc agccuaggug caaucguguc cugcuacggc aaaacaaaau     1200

gcaccgccuc caacaaaaau aaaggaauca uaaaaaccuu cuccaacggc ugcgacuacg     1260

ucagcaacaa aggagucgac accgucuccg uaggaaauac ucuauacuau gucaacaaac     1320

aagaggguaa aucccucuac gucaaaggcg aacccaucau caacuucuac gacccccucg     1380

ucuuccccuc ugacgaguuc gacgccagca uaucacaagu aaacgaaaag aucaaccaau     1440

cccucgcauu cauucgcaaa uccgacgaac uccuacacaa cgucaacgcc ggaaaaucca     1500

ccaccaacau caugaucacu acuaucauua ucgucaucau cgucauccuc cucucccuca     1560

ucgcagucgg ccuucuacuc uacugcaagg cacgcucuac acccguaacc cugucuaaag     1620

accaacucuc cggcaucaac aacaucgcuu ucuccaacua aggacuagug caucacauuu     1680

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1740

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1800

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1860

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1980

caccagaauu                                                            1990


<210>  7163
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7163
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagaug      300

cugaugugcu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

agcaacaucg agacggugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugug cagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga acaaggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccggagc     1560

acgcccguca cccuguccaa ggaccagcug agcggcauca acaacaucgc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7164
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt1)

<400>  7164
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagaug      300

cucaugugcu ccacccccgc caccggcagc ggguccgcca ucgccagcgg cguggcggug      360

ugcaaggucc ugcaccugga gggcgaggug aacaagauca aguccgcccu ccugagcacc      420

aacaaggccg uggucucccu gagcaacggg guguccgugc ucacguucaa gguccuggac      480

cugaagaacu acaucgacaa gcagcuccug ccgauccuga acaagcagag cugcuccauc      540

agcaacaucg agaccgugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguucu ccgugaacgc cggcgucacc acgcccguga gcaccuacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcugccc cucuacgggg ugaucgacac gccgugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacacgaagg agggcagcaa caucugccuc      900

acccgcaccg accgggggug guacugcgac aacgcgggcu ccgugagcuu cuucccccag      960

gccgagaccu gcaaggucug cuccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cugcccuccg aggucaaccu cugcaacgug gacaucuuca acccgaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg cgccaucgug     1140

uccugcuacg ggaagaccaa gugcaccgcc agcaacaaga acaagggcau caucaagacc     1200

uucuccaacg ggugcgacua cgugagcaac aagggcgucg acacggugag cgugggcaac     1260

acccuguacu acgucaacaa gcaggagggg aagucccucu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccuggcg uucauccgga aguccgacga gcuccugcac     1440

aacgugaacg ccgggaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc ugcucagccu gaucgccgug ggccugcucc uguacugcaa ggcccgcucc     1560

accccgguga cccugagcaa ggaccagcug uccgggauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7165
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt2)

<400>  7165
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagaug      300

cucaugugcu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

uccaacaucg agaccgucau ggaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucug cuccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga acaagggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu acgucaacaa gcaggagggc aagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcucc     1560

acccccguca cccucuccaa ggaccagcuc uccggcauca acaacaucgc cuucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7166
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt3)

<400>  7166
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagaug      300

cuuauguguu cuacacccgc caccggcucg gggucagcua uagcaagcgg aguggccguc      360

ugcaaggugc ugcacuugga gggcgaaguu aacaaaauca agagugcucu ccuguccacg      420

aauaaagccg uggucucucu gagcaacggu guguccguac ucacuuuuaa gguuuuagac      480

cugaagaauu acauugauaa acagcuuuug ccuauccuga acaagcaauc auguaguauu      540

agcaauaucg agaccgugau ggaguuccag cagaaaaaca auaggcuacu cgaaauaaca      600

cgggaguuuu cugucaacgc gggggugacu accccagugu ccacauauau gcugaccaau      660

ucagaacuuc ugagcuugau uaacgacaug ccgaucacga acgaucagaa gaaacucaug      720

aguaauaacg uccaaauugu ucgccagcag ucuuacucca ucaugugcau cauuaaggag      780

gaagugcugg cauauguagu gcaguuaccc cuguacggag ucauagacac uccuuguugg      840

aaacuccaua caagcccacu uugcaccacu aauacaaagg agggcucgaa caucugucug      900

acccgaacgg aucguggcug guacugcgac aaugccgggu cuguguccuu cuuuccccaa      960

gcugaaaccu guaagguuug cucaaacaga guguucugcg auacaaugaa uaguuugacu     1020

cuaccuagcg aggucaaccu guguaaugug gacauuuuua acccaaaaua ugauugcaag     1080

aucaugaccu ccaaaacaga cguaucuagc ucaguuauaa cuagccucgg agccauugug     1140

uccuguuacg guaagaccaa augcacagca agcaauaaga acaagggcau caucaaaacc     1200

uucucuaaug ggugugauua ugucucaaac aagggagugg acacugucag ugugggcaau     1260

acgcuguacu auguuaacaa acaggagggu aagagccuuu acgugaaagg ggaacccauu     1320

aucaacuuuu augacccucu gguauuccca uccgaugagu uugacgcuuc uauuucgcag     1380

gucaaugaaa agauaaacca aaguuuggcc uucaucagga aguccgauga gcuccugcac     1440

aaugugaacg cgggaaaauc aacaaccaau auuaugauca cuaccaucau uauaguuauc     1500

auugugaucu uacugagucu aauugccguc ggccuccugc uuuacugcaa ggcacggucu     1560

acaccgguga ccuugagcaa agaccagcug uccggcauca acaauauagc uuucucaaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7167
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt4)

<400>  7167
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagaug      300

cugaugugca gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

agcaacaucg agaccgugau ggaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugug cagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acaagggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagaagc     1560

acccccguga cccugagcaa ggaccagcug agcggcauca acaacaucgc cuucagcaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7168
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt5)

<400>  7168
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagaug      300

cugauguguu ccacccccgc cacagggucu ggaagcgcua uugccuccgg cgucgcggug      360

ugcaagguuc ugcaccucga gggggaagug aacaaaauca agagcgcccu gcuuucuacc      420

aauaaagcug ucgugucccu gagcaacgga guuucugugc ucacauuuaa gguccuggac      480

cuuaagaauu acauugauaa acagcugcuc ccuauccuga acaagcaauc cuguagcauu      540

ucuaauaucg agaccgugau ggaguuccag cagaaaaaca aucggcugcu cgaaauuacg      600

cgcgaguuuu ccgugaacgc cggcgucaca accccgguua gcacauauau gcugaccaau      660

uccgaacuuc ugucucucau caacgacaug cccaucacca acgaucagaa gaaacugaug      720

agcaauaacg ugcaaauugu gagacagcag uccuacagca ucaugugcau uaucaaggag      780

gaaguccuug cuuauguggu ucagcugccu cucuacggcg ugauugacac acccuguugg      840

aaacugcaua cgucuccucu gugcaccaca aauaccaagg agggguccaa caucugucuc      900

acacggaccg aucgcggaug guacugcgac aaugccggca gcgucucuuu cuuuccccaa      960

gcggaaacgu guaaggugug cagcaacaga guuuucugcg auacaaugaa cucccugacc     1020

cuuccuucug aggugaaucu guguaauguc gacaucuuua acccgaaaua ugauugcaag     1080

auuaugacca gcaaaacaga cguguccagc ucugucauca ccucccucgg ggccauugug     1140

agcuguuacg gaaagacaaa augcacggcu ucuaauaaga acaagggcau cauuaaaacc     1200

uucuccaaug ggugugauua uguuagcaac aagggagugg acacagucuc cgugggcaau     1260

acccuguacu auguuaacaa acaggagggc aagucucuuu acgugaaagg ggaacccauc     1320

aucaacuuuu augacccucu ggucuucccc agcgaugagu uugacgccuc cauuucucag     1380

gugaaugaaa agaucaacca aagccucgcu uucauucgga aguccgauga gcugcugcac     1440

aaugugaacg ccggaaaaag cacaaccaau aucaugauua cgaccaucau uaucguuauc     1500

auugucaucc uccugucucu uauugccgug ggccugcucc uguacugcaa ggcucgcucc     1560

acaccuguga cccugagcaa agaccagcuu ucugggauca acaauauugc guucuccaac     1620

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7169
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt6)

<400>  7169
gggagaaagc uuaccaugga auuacucaua cucaaagcaa augcaauuac cacuauacuc       60

acagcuguaa cuuuuuguuu cgccucagga caaaacauca cagaagaauu uuaucaaucc      120

acaugcucug ccguaucaaa aggcuaccua ucugcccuaa gaacagguug guacacaucu      180

guaauaacaa ucgaauuauc caacaucaaa gaaaacaaau gcaacggcac agacgcaaaa      240

gucaaacuca ucaaacaaga auuagauaaa uauaaaaacg caguaacaga acuacaaaug      300

cuaaugugcu cuacacccgc cacaggauca ggauccgcaa ucgcuucugg aguagccguu      360

ugcaaaguau uacaccuaga aggagaagua aauaaaauaa aauccgcacu acuaucaacu      420

aauaaagcag uaguaucacu uucuaauggu guaucaguau uaacauucaa aguccucgac      480

cuaaaaaauu acaucgacaa acaacuauua cccauccuua auaaacaauc augcuccaua      540

ucaaacauag aaacugucau ggaauuucaa caaaaaaaca auagacuucu agaaaucaca      600

agagaauuuu cuguaaaugc aggaguaacu acaccaguau caacauauau guuaaccaac      660

uccgaacuac uaucacucau aaacgacaug ccaauaacaa acgaccaaaa aaaacuaaug      720

ucaaauaacg uucaaauagu aagacaacaa ucauacucaa ucaugugcau aauaaaagaa      780

gaaguuuuag cauacgucgu acaacuuccc cuauacggag uaauagacac cccuugcugg      840

aaacuccaca ccucaccacu augcacuaca aacacaaaag aagguuccaa caucugcuua      900

acaagaaccg aucgaggaug guacugcgac aacgcugguu ccguaucuuu cuucccacaa      960

gcagaaacau gcaaaguaug cuccaauaga guauucugcg acaccaugaa cucacuaacu     1020

cuaccauccg aaguaaaccu augcaacguc gacauauuua auccaaaaua ugacugcaaa     1080

auaaugacuu caaaaacaga cguauccuca ucaguaauaa cauccuuagg agcaauagua     1140

ucauguuacg gcaagacaaa auguacagcc ucaaacaaaa acaaagguau cauuaaaacc     1200

uucuccaacg gcugcgacua cguaucaaau aaaggugucg auacaguauc aguaggaaac     1260

acacucuauu acguuaauaa acaagaagga aagucauuau acguaaaagg agaaccaaua     1320

aucaauuucu acgauccccu agucuuuccc ucagaugaau uugacgcaag caucucucaa     1380

gucaacgaaa aaauaaacca aucccuagcc uucauaagaa aaucagauga acuacuucau     1440

aacgucaacg ccggaaaauc aacaaccaac auaaugauca cuacaaucau aauuguaauu     1500

auaguaauac uacuaucgcu aauugccguu ggacuacuac uauauuguaa agcaagauca     1560

acacccguua cucuauccaa agaucaauua ucaggaauca acaacauagc cuucucaaau     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7170
<211>  1825
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut7 (opt11)

<400>  7170
gggagaaagc uuaccaugga acuacucaua cuuaaagcca acgcaauaac cacaauccuc       60

accgccguca cauucugcuu cgccucggga caaaacauaa ccgaagaauu uuaccagucu      120

accugcuccg ccgucuccaa ggguuaccuc uccgcgcucc gcaccgggug guacaccagc      180

guuaucacca ucgaacuauc uaacauaaaa gaaaacaagu gcaacggaac cgacgcaaaa      240

gucaaacuca ucaaacaaga acuagacaaa uacaagaaug ccgucaccga acuacaaaug      300

cucaugugcu ccacccccgc caccggaucc ggcuccgcca uugccuccgg cgucgccgua      360

ugcaaagucc uucacuugga aggagaaguu aacaaaauaa aaagcgcccu ccugucgacc      420

aacaaagcgg uggucagccu cuccaacggc gucucugucc ucaccuucaa aguccucgac      480

cucaagaacu acauagauaa acaacuacuc cccauccuaa acaaacaguc augcagcaua      540

uccaacaucg aaaccgucau ggaguuccaa cagaaaaaca accgccuccu ugaaaucacc      600

cgcgaguucu cugucaacgc cggcgucacc acccccgucu ccaccuacau gcucacaaac      660

uccgaacucc ucagccucau caacgacaug ccaaucacca acgaccaaaa gaaacucaug      720

uccaacaacg uacaaaucgu ucgucaacaa ucauacucaa ucaugugcau cauuaaagaa      780

gaaguccucg cauacgucgu ccaacucccc cucuaugggg ucaucgacac cccaugcugg      840

aaacuccaca ccucuccccu augcaccacc aacaccaaag aaggcuccaa caucugccua      900

acccgaaccg accgcggaug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgaaacau guaaagucug cuccaaccgu guguucugcg acaccaugaa cucacuaacc     1020

cuccccuccg aagucaaccu cugcaacguc gacaucuuca acccgaaaua cgacugcaaa     1080

auaaugacca gcaaaacaga cguauccucu agcgucauua ccagccuagg ugcaaucgug     1140

uccugcuacg gcaaaacaaa augcaccgcc uccaacaaaa auaaaggaau cauaaaaacc     1200

uucuccaacg gcugcgacua cgucagcaac aaaggagucg acaccgucuc cguaggaaau     1260

acucuauacu augucaacaa acaagagggu aaaucccucu acgucaaagg cgaacccauc     1320

aucaacuucu acgacccccu cgucuucccc ucugacgagu ucgacgccag cauaucacaa     1380

guaaacgaaa agaucaacca aucccucgca uucauucgca aauccgacga acuccuacac     1440

aacgucaacg ccggaaaauc caccaccaac aucaugauca cuacuaucau uaucgucauc     1500

aucgucaucc uccucucccu caucgcaguc ggccuucuac ucuacugcaa ggcacgcucu     1560

acacccguaa cccugucuaa agaccaacuc uccggcauca acaacaucgc uuucuccaac     1620

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1680

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1800

ggcucuuuuc agagccacca gaauu                                           1825


<210>  7171
<211>  514
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7171

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Met Leu 
                85                  90                  95      


Met Cys Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Asn 
    130                 135                 140                 


Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr Ile 
145                 150                 155                 160 


Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile Ser 
                165                 170                 175     


Asn Ile Glu Thr Val Met Glu Phe Gln Gln Lys Asn Asn Arg Leu Leu 
            180                 185                 190         


Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro Val 
        195                 200                 205             


Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn Asp 
    210                 215                 220                 


Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val Gln 
225                 230                 235                 240 


Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu Glu 
                245                 250                 255     


Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp Thr 
            260                 265                 270         


Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr Lys 
        275                 280                 285             


Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr Cys 
    290                 295                 300                 


Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys Lys 
305                 310                 315                 320 


Val Cys Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr Leu 
                325                 330                 335     


Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys Tyr 
            340                 345                 350         


Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val Ile 
        355                 360                 365             


Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys Thr 
    370                 375                 380                 


Ala Ser Asn Lys Asn Lys Gly Ile Ile Lys Thr Phe Ser Asn Gly Cys 
385                 390                 395                 400 


Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn Thr 
                405                 410                 415     


Leu Tyr Tyr Val Asn Lys Gln Glu Gly Lys Ser Leu Tyr Val Lys Gly 
            420                 425                 430         


Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp Glu 
        435                 440                 445             


Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser Leu 
    450                 455                 460                 


Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala Gly 
465                 470                 475                 480 


Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile Ile 
                485                 490                 495     


Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys Lys 
            500                 505                 510         


Ala Arg 
        


<210>  7172
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7172
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agaugcugau gugcuccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucucca acggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccaucagcaa caucgagacg      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      600

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      780

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      840

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      900

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag      960

gugugcagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1140

acgaagugca ccgccagcaa caagaacaag gggaucauca agaccuucuc caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1320

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1440

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1500

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc gguga                     1545


<210>  7173
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7173
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucagcgc ccugcgcacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggagcugc agaugcucau gugcuccacc      300

cccgccaccg gcagcggguc cgccaucgcc agcggcgugg cggugugcaa gguccugcac      360

cuggagggcg aggugaacaa gaucaagucc gcccuccuga gcaccaacaa ggccgugguc      420

ucccugagca acgggguguc cgugcucacg uucaaggucc uggaccugaa gaacuacauc      480

gacaagcagc uccugccgau ccugaacaag cagagcugcu ccaucagcaa caucgagacc      540

gugauggagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucuccgug      600

aacgccggcg ucaccacgcc cgugagcacc uacaugcuga ccaacagcga gcuccugucc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ucaugagcaa caacgugcag      720

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

gugguccagc ugccccucua cggggugauc gacacgccgu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac gaaggagggc agcaacaucu gccucacccg caccgaccgg      900

gggugguacu gcgacaacgc gggcuccgug agcuucuucc cccaggccga gaccugcaag      960

gucugcucca accgcguguu cugcgacacg augaacagcc ugacccugcc cuccgagguc     1020

aaccucugca acguggacau cuucaacccg aaguacgacu gcaagaucau gaccagcaag     1080

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1140

accaagugca ccgccagcaa caagaacaag ggcaucauca agaccuucuc caacgggugc     1200

gacuacguga gcaacaaggg cgucgacacg gugagcgugg gcaacacccu guacuacguc     1260

aacaagcagg aggggaaguc ccucuacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1380

aaccaguccc uggcguucau ccggaagucc gacgagcucc ugcacaacgu gaacgccggg     1440

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccugcuc     1500

agccugaucg ccgugggccu gcuccuguac ugcaaggccc gcuga                     1545


<210>  7174
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7174
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucuccgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgagcucc agaugcucau gugcuccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucucca acggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      480

gacaagcagc uccuccccau ccucaacaag caguccugcu ccaucuccaa caucgagacc      540

gucauggagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      600

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      660

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      720

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      780

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      840

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      900

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag      960

gucugcucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1020

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1080

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1140

accaagugca ccgccuccaa caagaacaag ggcaucauca agaccuucuc caacggcugc     1200

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1260

aacaagcagg agggcaaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1380

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1440

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1500

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuga                     1545


<210>  7175
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7175
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugagugc uuuaagaacu ggaugguaca ccagcguuau uacaaucgaa      180

cuguccaaca uuaaggagaa uaaaugcaac gguaccgacg ccaaggugaa acuaaucaag      240

caggaacucg auaaguauaa aaaugcagua acugagcugc agaugcuuau guguucuaca      300

cccgccaccg gcucgggguc agcuauagca agcggagugg ccgucugcaa ggugcugcac      360

uuggagggcg aaguuaacaa aaucaagagu gcucuccugu ccacgaauaa agccgugguc      420

ucucugagca acgguguguc cguacucacu uuuaagguuu uagaccugaa gaauuacauu      480

gauaaacagc uuuugccuau ccugaacaag caaucaugua guauuagcaa uaucgagacc      540

gugauggagu uccagcagaa aaacaauagg cuacucgaaa uaacacggga guuuucuguc      600

aacgcggggg ugacuacccc aguguccaca uauaugcuga ccaauucaga acuucugagc      660

uugauuaacg acaugccgau cacgaacgau cagaagaaac ucaugaguaa uaacguccaa      720

auuguucgcc agcagucuua cuccaucaug ugcaucauua aggaggaagu gcuggcauau      780

guagugcagu uaccccugua cggagucaua gacacuccuu guuggaaacu ccauacaagc      840

ccacuuugca ccacuaauac aaaggagggc ucgaacaucu gucugacccg aacggaucgu      900

ggcugguacu gcgacaaugc cgggucugug uccuucuuuc cccaagcuga aaccuguaag      960

guuugcucaa acagaguguu cugcgauaca augaauaguu ugacucuacc uagcgagguc     1020

aaccugugua auguggacau uuuuaaccca aaauaugauu gcaagaucau gaccuccaaa     1080

acagacguau cuagcucagu uauaacuagc cucggagcca uuguguccug uuacgguaag     1140

accaaaugca cagcaagcaa uaagaacaag ggcaucauca aaaccuucuc uaaugggugu     1200

gauuaugucu caaacaaggg aguggacacu gucagugugg gcaauacgcu guacuauguu     1260

aacaaacagg aggguaagag ccuuuacgug aaaggggaac ccauuaucaa cuuuuaugac     1320

ccucugguau ucccauccga ugaguuugac gcuucuauuu cgcaggucaa ugaaaagaua     1380

aaccaaaguu uggccuucau caggaagucc gaugagcucc ugcacaaugu gaacgcggga     1440

aaaucaacaa ccaauauuau gaucacuacc aucauuauag uuaucauugu gaucuuacug     1500

agucuaauug ccgucggccu ccugcuuuac ugcaaggcac gguga                     1545


<210>  7176
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7176
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugagcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagaa caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgagcugc agaugcugau gugcagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagca acggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      480

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcaucagcaa caucgagacc      540

gugauggagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      600

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      660

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      720

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      780

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      840

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      900

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag      960

gugugcagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1020

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1080

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1140

accaagugca ccgccagcaa caagaacaag ggcaucauca agaccuucag caacggcugc     1200

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1260

aacaagcagg agggcaagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1320

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1380

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1440

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1500

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gauga                     1545


<210>  7177
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7177
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucuguccgc ccucagaaca ggaugguaca ccucuguuau cacaauugaa      180

cugagcaaca ucaaggagaa uaaaugcaac ggcaccgacg ccaaggugaa acuuaucaag      240

caggaacugg auaaguauaa aaaugcugug acggagcucc agaugcugau guguuccacc      300

cccgccacag ggucuggaag cgcuauugcc uccggcgucg cggugugcaa gguucugcac      360

cucgaggggg aagugaacaa aaucaagagc gcccugcuuu cuaccaauaa agcugucgug      420

ucccugagca acggaguuuc ugugcucaca uuuaaggucc uggaccuuaa gaauuacauu      480

gauaaacagc ugcucccuau ccugaacaag caauccugua gcauuucuaa uaucgagacc      540

gugauggagu uccagcagaa aaacaaucgg cugcucgaaa uuacgcgcga guuuuccgug      600

aacgccggcg ucacaacccc gguuagcaca uauaugcuga ccaauuccga acuucugucu      660

cucaucaacg acaugcccau caccaacgau cagaagaaac ugaugagcaa uaacgugcaa      720

auugugagac agcaguccua cagcaucaug ugcauuauca aggaggaagu ccuugcuuau      780

gugguucagc ugccucucua cggcgugauu gacacacccu guuggaaacu gcauacgucu      840

ccucugugca ccacaaauac caaggagggg uccaacaucu gucucacacg gaccgaucgc      900

ggaugguacu gcgacaaugc cggcagcguc ucuuucuuuc cccaagcgga aacguguaag      960

gugugcagca acagaguuuu cugcgauaca augaacuccc ugacccuucc uucugaggug     1020

aaucugugua augucgacau cuuuaacccg aaauaugauu gcaagauuau gaccagcaaa     1080

acagacgugu ccagcucugu caucaccucc cucggggcca uugugagcug uuacggaaag     1140

acaaaaugca cggcuucuaa uaagaacaag ggcaucauua aaaccuucuc caaugggugu     1200

gauuauguua gcaacaaggg aguggacaca gucuccgugg gcaauacccu guacuauguu     1260

aacaaacagg agggcaaguc ucuuuacgug aaaggggaac ccaucaucaa cuuuuaugac     1320

ccucuggucu uccccagcga ugaguuugac gccuccauuu cucaggugaa ugaaaagauc     1380

aaccaaagcc ucgcuuucau ucggaagucc gaugagcugc ugcacaaugu gaacgccgga     1440

aaaagcacaa ccaauaucau gauuacgacc aucauuaucg uuaucauugu cauccuccug     1500

ucucuuauug ccgugggccu gcuccuguac ugcaaggcuc gcuga                     1545


<210>  7178
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7178
auggaauuac uaauccucaa agcaaacgca auuacaacca uacuaaccgc ugucaccuuu       60

uguuuugccu caggacaaaa cauaacugaa gaauuuuacc aaucaacaug cuccgcagua      120

ucuaaaggau accucagcgc guuaagaaca ggaugguaca caucgguaau aaccaucgaa      180

uuauccaaca uaaaagaaaa uaaaugcaau ggaacagacg caaaagucaa auuaauuaaa      240

caagaacuag acaaauauaa aaacgcagua accgaauuac aaaugcuaau guguucaaca      300

ccagcaacag gaucaggauc agcuauagcu ucaggaguug ccguaugcaa agugcuacac      360

uuagaaggag aagugaauaa aauaaaauca gcucuauuau caacgaacaa agccguagua      420

ucucuaucaa auggcguauc aguacucaca uucaaaguac ucgaccuaaa aaacuauaua      480

gauaaacaac uauuacccau ccuaaauaaa caaagcugcu cuauaucaaa caucgaaaca      540

guaauggaau uucaacaaaa aaacaacaga cuacuagaaa uaacccgaga guucucaguu      600

aaugcaggag uaacaacacc agucucaaca uacaugcuca caaacucaga acuccuauca      660

cuaauaaaug acaugccaau aacaaacgac caaaaaaaac ucaugucuaa caacguccaa      720

auaguaagac aacaauccua cagcauaaug uguauaauaa aagaagaagu uuuagcauac      780

gucguacaac uacccuuaua uggcguaaua gauacaccau gcuggaaacu ccauaccuca      840

ccucuaugua caacaaauac caaagaaggu ucuaauauau gccuaacacg aacugaccga      900

ggaugguacu gugacaacgc aggaucaguc ucuuucuuuc cacaagcaga aaccugcaaa      960

guaugcagua accgcguauu uugcgacaca augaacuccc uaaccuuacc aucagaagua     1020

aacuuaugua acguagacau auucaaucca aaauaugacu gcaaaauaau gacaucaaaa     1080

acagacguaa gcucaucagu aauaacuuca cuaggcgcaa uuguaucaug cuauggaaaa     1140

accaaaugua ccgcauccaa caaaaauaaa ggaauaauaa aaaccuucuc uaacggaugc     1200

gacuacguau caaacaaagg uguagauaca guuucuguag gaaacacacu cuacuaugua     1260

aauaaacaag aaggaaaauc acuauacgua aaaggagaac caauaauaaa cuucuaugac     1320

ccacuuguau uuccaucuga ugaauuugau gcaagcauau cacaaguaaa cgaaaaaaua     1380

aaccaaucuc uagccuuuau acgaaaaagc gacgaauuac uacauaacgu caacgcugga     1440

aaaucaacaa caaacauaau gauaacaaca auaauaauag uaauaauagu cauccuauua     1500

ucacuaaucg ccguaggacu acuccuauac ugcaaagcua gauaa                     1545


<210>  7179
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut7

<400>  7179
auggaacucc ucauccucaa agccaacgcc auaaccacua uccucacagc agucacuuuc       60

ugcuucgccu caggacaaaa cauaaccgaa gaguucuacc aauccacaug cuccgccguc      120

uccaaaggcu accucucagc gcuccgcacc ggcugguaca cauccgucau caccaucgaa      180

cuaagcaaca uaaaagaaaa caaaugcaac ggcaccgacg ccaaaguuaa acucaucaag      240

caagaacucg acaaauacaa aaacgcaguc acagaacuuc aaaugcucau gugcuccaca      300

cccgccacag guucuggcuc agcaaucgca agcggcgucg ccguaugcaa aguccuucac      360

cucgaaggcg aagucaacaa aaucaaaucc gcccuccucu ccaccaauaa agcugucguc      420

ucacucucca acggcgucag cguccucaca uucaaagucc ucgaccucaa aaacuacaua      480

gacaagcaac uccucccgau acucaacaaa caaagcugcu cuaucuccaa caucgaaacc      540

gucauggagu uccaacagaa aaacaaucgu cuccucgaaa ucacccgcga guucucagua      600

aacgccgggg ucaccacacc agucuccacc uacaugcuca ccaacuccga acuccuuagc      660

cucauaaacg acaugcccau aaccaacgac caaaagaaac ucaugagcaa caacguacaa      720

auaguccgac aacaauccua uuccaucaug uguaucauca aagaagaagu ccucgcauac      780

guaguccaac ucccccuaua cggcguaauc gacaccccau guuggaaacu ccacaccuca      840

ccacucugua ccaccaacac caaagaaggc ucaaacaucu gccucacccg cacagaccgc      900

ggcugguacu gcgacaacgc gggcuccguc agcuucuuuc cccaagcgga aaccugcaaa      960

gucugcagca acagagucuu cugcgacacu augaacuccc ucacccuccc cucagaaguc     1020

aaccucugca acgucgacau cuucaacccg aaauacgacu gcaaaaucau gaccagcaaa     1080

acugacgucu ccucguccgu caucaccuca cucggcgcaa ucgugagcug cuacggcaaa     1140

accaaaugca ccgccuccaa caaaaacaaa ggcaucauaa aaacauucag caacggcugc     1200

gacuacgucu cgaacaaagg agucgacacc guaucagugg gcaacacccu auacuacgua     1260

aacaagcaag aaggcaaauc acucuacgua aaaggcgaac ccaucaucaa cuucuacgac     1320

ccccucgucu uccccuccga cgaguucgac gccuccaucu cucaagucaa cgagaaaauc     1380

aaccaauccc uugccuucau acguaaaagc gacgaacucc uucacaacgu aaacgccggg     1440

aaauccacca cuaacauaau gaucaccacc aucaucaucg uuaucauagu cauccuccuc     1500

ucucucauag cagucggccu acuccuguac ugcaaagcgc gcuaa                     1545


<210>  7180
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7180
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7181
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7181
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7182
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7182
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7183
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7183
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7184
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7184
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7185
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7185
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7186
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7186
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccucaaagc aaacgcaauu acaaccauac      120

uaaccgcugu caccuuuugu uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacaugcuc cgcaguaucu aaaggauacc ucagcgcguu aagaacagga ugguacacau      240

cgguaauaac caucgaauua uccaacauaa aagaaaauaa augcaaugga acagacgcaa      300

aagucaaauu aauuaaacaa gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa      360

ugcuaaugug uucaacacca gcaacaggau caggaucagc uauagcuuca ggaguugccg      420

uaugcaaagu gcuacacuua gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa      480

cgaacaaagc cguaguaucu cuaucaaaug gcguaucagu acucacauuc aaaguacucg      540

accuaaaaaa cuauauagau aaacaacuau uacccauccu aaauaaacaa agcugcucua      600

uaucaaacau cgaaacagua auggaauuuc aacaaaaaaa caacagacua cuagaaauaa      660

cccgagaguu cucaguuaau gcaggaguaa caacaccagu cucaacauac augcucacaa      720

acucagaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa cguccaaaua guaagacaac aauccuacag cauaaugugu auaauaaaag      840

aagaaguuuu agcauacguc guacaacuac ccuuauaugg cguaauagau acaccaugcu      900

ggaaacucca uaccucaccu cuauguacaa caaauaccaa agaagguucu aauauaugcc      960

uaacacgaac ugaccgagga ugguacugug acaacgcagg aucagucucu uucuuuccac     1020

aagcagaaac cugcaaagua ugcaguaacc gcguauuuug cgacacaaug aacucccuaa     1080

ccuuaccauc agaaguaaac uuauguaacg uagacauauu caauccaaaa uaugacugca     1140

aaauaaugac aucaaaaaca gacguaagcu caucaguaau aacuucacua ggcgcaauug     1200

uaucaugcua uggaaaaacc aaauguaccg cauccaacaa aaauaaagga auaauaaaaa     1260

ccuucucuaa cggaugcgac uacguaucaa acaaaggugu agauacaguu ucuguaggaa     1320

acacacucua cuauguaaau aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca cuuguauuuc caucugauga auuugaugca agcauaucac     1440

aaguaaacga aaaaauaaac caaucucuag ccuuuauacg aaaaagcgac gaauuacuac     1500

auaacgucaa cgcuggaaaa ucaacaacaa acauaaugau aacaacaaua auaauaguaa     1560

uaauagucau ccuauuauca cuaaucgccg uaggacuacu ccuauacugc aaagcuagau     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7187
<211>  1821
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7187
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacuaucc      120

ucacagcagu cacuuucugc uucgccucag gacaaaacau aaccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau      240

ccgucaucac caucgaacua agcaacauaa aagaaaacaa augcaacggc accgacgcca      300

aaguuaaacu caucaagcaa gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa      360

ugcucaugug cuccacaccc gccacagguu cuggcucagc aaucgcaagc ggcgucgccg      420

uaugcaaagu ccuucaccuc gaaggcgaag ucaacaaaau caaauccgcc cuccucucca      480

ccaauaaagc ugucgucuca cucuccaacg gcgucagcgu ccucacauuc aaaguccucg      540

accucaaaaa cuacauagac aagcaacucc ucccgauacu caacaaacaa agcugcucua      600

ucuccaacau cgaaaccguc auggaguucc aacagaaaaa caaucgucuc cucgaaauca      660

cccgcgaguu cucaguaaac gccgggguca ccacaccagu cuccaccuac augcucacca      720

acuccgaacu ccuuagccuc auaaacgaca ugcccauaac caacgaccaa aagaaacuca      780

ugagcaacaa cguacaaaua guccgacaac aauccuauuc caucaugugu aucaucaaag      840

aagaaguccu cgcauacgua guccaacucc cccuauacgg cguaaucgac accccauguu      900

ggaaacucca caccucacca cucuguacca ccaacaccaa agaaggcuca aacaucugcc      960

ucacccgcac agaccgcggc ugguacugcg acaacgcggg cuccgucagc uucuuucccc     1020

aagcggaaac cugcaaaguc ugcagcaaca gagucuucug cgacacuaug aacucccuca     1080

cccuccccuc agaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaaucaugac cagcaaaacu gacgucuccu cguccgucau caccucacuc ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

cauucagcaa cggcugcgac uacgucucga acaaaggagu cgacaccgua ucagugggca     1320

acacccuaua cuacguaaac aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucucuc     1440

aagucaacga gaaaaucaac caaucccuug ccuucauacg uaaaagcgac gaacuccuuc     1500

acaacguaaa cgccgggaaa uccaccacua acauaaugau caccaccauc aucaucguua     1560

ucauagucau ccuccucucu cucauagcag ucggccuacu ccuguacugc aaagcgcgcu     1620

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1680

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1800

cuuuucagag ccaccagaau u                                               1821


<210>  7188
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7188
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7189
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7189
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7190
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7190
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7191
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7191
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacggug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7192
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7192
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7193
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7193
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7194
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7194
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccucaaagca      120

aacgcaauua caaccauacu aaccgcuguc accuuuuguu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacaugcucc gcaguaucua aaggauaccu cagcgcguua      240

agaacaggau gguacacauc gguaauaacc aucgaauuau ccaacauaaa agaaaauaaa      300

ugcaauggaa cagacgcaaa agucaaauua auuaaacaag aacuagacaa auauaaaaac      360

gcaguaaccg aauuacaaau gcuaaugugu ucaacaccag caacaggauc aggaucagcu      420

auagcuucag gaguugccgu augcaaagug cuacacuuag aaggagaagu gaauaaaaua      480

aaaucagcuc uauuaucaac gaacaaagcc guaguaucuc uaucaaaugg cguaucagua      540

cucacauuca aaguacucga ccuaaaaaac uauauagaua aacaacuauu acccauccua      600

aauaaacaaa gcugcucuau aucaaacauc gaaacaguaa uggaauuuca acaaaaaaac      660

aacagacuac uagaaauaac ccgagaguuc ucaguuaaug caggaguaac aacaccaguc      720

ucaacauaca ugcucacaaa cucagaacuc cuaucacuaa uaaaugacau gccaauaaca      780

aacgaccaaa aaaaacucau gucuaacaac guccaaauag uaagacaaca auccuacagc      840

auaaugugua uaauaaaaga agaaguuuua gcauacgucg uacaacuacc cuuauauggc      900

guaauagaua caccaugcug gaaacuccau accucaccuc uauguacaac aaauaccaaa      960

gaagguucua auauaugccu aacacgaacu gaccgaggau gguacuguga caacgcagga     1020

ucagucucuu ucuuuccaca agcagaaacc ugcaaaguau gcaguaaccg cguauuuugc     1080

gacacaauga acucccuaac cuuaccauca gaaguaaacu uauguaacgu agacauauuc     1140

aauccaaaau augacugcaa aauaaugaca ucaaaaacag acguaagcuc aucaguaaua     1200

acuucacuag gcgcaauugu aucaugcuau ggaaaaacca aauguaccgc auccaacaaa     1260

aauaaaggaa uaauaaaaac cuucucuaac ggaugcgacu acguaucaaa caaaggugua     1320

gauacaguuu cuguaggaaa cacacucuac uauguaaaua aacaagaagg aaaaucacua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccac uuguauuucc aucugaugaa     1440

uuugaugcaa gcauaucaca aguaaacgaa aaaauaaacc aaucucuagc cuuuauacga     1500

aaaagcgacg aauuacuaca uaacgucaac gcuggaaaau caacaacaaa cauaaugaua     1560

acaacaauaa uaauaguaau aauagucauc cuauuaucac uaaucgccgu aggacuacuc     1620

cuauacugca aagcuagaua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7195
<211>  1840
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7195
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacuauccu cacagcaguc acuuucugcu ucgccucagg acaaaacaua      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca aaggcuaccu cucagcgcuc      240

cgcaccggcu gguacacauc cgucaucacc aucgaacuaa gcaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa aguuaaacuc aucaagcaag aacucgacaa auacaaaaac      360

gcagucacag aacuucaaau gcucaugugc uccacacccg ccacagguuc uggcucagca      420

aucgcaagcg gcgucgccgu augcaaaguc cuucaccucg aaggcgaagu caacaaaauc      480

aaauccgccc uccucuccac caauaaagcu gucgucucac ucuccaacgg cgucagcguc      540

cucacauuca aaguccucga ccucaaaaac uacauagaca agcaacuccu cccgauacuc      600

aacaaacaaa gcugcucuau cuccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaucgucucc ucgaaaucac ccgcgaguuc ucaguaaacg ccggggucac cacaccaguc      720

uccaccuaca ugcucaccaa cuccgaacuc cuuagccuca uaaacgacau gcccauaacc      780

aacgaccaaa agaaacucau gagcaacaac guacaaauag uccgacaaca auccuauucc      840

aucaugugua ucaucaaaga agaaguccuc gcauacguag uccaacuccc ccuauacggc      900

guaaucgaca ccccauguug gaaacuccac accucaccac ucuguaccac caacaccaaa      960

gaaggcucaa acaucugccu cacccgcaca gaccgcggcu gguacugcga caacgcgggc     1020

uccgucagcu ucuuucccca agcggaaacc ugcaaagucu gcagcaacag agucuucugc     1080

gacacuauga acucccucac ccuccccuca gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aaucaugacc agcaaaacug acgucuccuc guccgucauc     1200

accucacucg gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac auucagcaac ggcugcgacu acgucucgaa caaaggaguc     1320

gacaccguau cagugggcaa cacccuauac uacguaaaca agcaagaagg caaaucacuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucucuca agucaacgag aaaaucaacc aaucccuugc cuucauacgu     1500

aaaagcgacg aacuccuuca caacguaaac gccgggaaau ccaccacuaa cauaaugauc     1560

accaccauca ucaucguuau cauagucauc cuccucucuc ucauagcagu cggccuacuc     1620

cuguacugca aagcgcgcua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1680

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1800

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1840


<210>  7196
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7196
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7197
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7197
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7198
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7198
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7199
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7199
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7200
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7200
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7201
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7201
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcugag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7202
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7202
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ucaaagcaaa cgcaauuaca accauacuaa ccgcugucac cuuuuguuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa caugcuccgc aguaucuaaa      300

ggauaccuca gcgcguuaag aacaggaugg uacacaucgg uaauaaccau cgaauuaucc      360

aacauaaaag aaaauaaaug caauggaaca gacgcaaaag ucaaauuaau uaaacaagaa      420

cuagacaaau auaaaaacgc aguaaccgaa uuacaaaugc uaauguguuc aacaccagca      480

acaggaucag gaucagcuau agcuucagga guugccguau gcaaagugcu acacuuagaa      540

ggagaaguga auaaaauaaa aucagcucua uuaucaacga acaaagccgu aguaucucua      600

ucaaauggcg uaucaguacu cacauucaaa guacucgacc uaaaaaacua uauagauaaa      660

caacuauuac ccauccuaaa uaaacaaagc ugcucuauau caaacaucga aacaguaaug      720

gaauuucaac aaaaaaacaa cagacuacua gaaauaaccc gagaguucuc aguuaaugca      780

ggaguaacaa caccagucuc aacauacaug cucacaaacu cagaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacucaugu cuaacaacgu ccaaauagua      900

agacaacaau ccuacagcau aauguguaua auaaaagaag aaguuuuagc auacgucgua      960

caacuacccu uauauggcgu aauagauaca ccaugcugga aacuccauac cucaccucua     1020

uguacaacaa auaccaaaga agguucuaau auaugccuaa cacgaacuga ccgaggaugg     1080

uacugugaca acgcaggauc agucucuuuc uuuccacaag cagaaaccug caaaguaugc     1140

aguaaccgcg uauuuugcga cacaaugaac ucccuaaccu uaccaucaga aguaaacuua     1200

uguaacguag acauauucaa uccaaaauau gacugcaaaa uaaugacauc aaaaacagac     1260

guaagcucau caguaauaac uucacuaggc gcaauuguau caugcuaugg aaaaaccaaa     1320

uguaccgcau ccaacaaaaa uaaaggaaua auaaaaaccu ucucuaacgg augcgacuac     1380

guaucaaaca aagguguaga uacaguuucu guaggaaaca cacucuacua uguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaagga gaaccaauaa uaaacuucua ugacccacuu     1500

guauuuccau cugaugaauu ugaugcaagc auaucacaag uaaacgaaaa aauaaaccaa     1560

ucucuagccu uuauacgaaa aagcgacgaa uuacuacaua acgucaacgc uggaaaauca     1620

acaacaaaca uaaugauaac aacaauaaua auaguaauaa uagucauccu auuaucacua     1680

aucgccguag gacuacuccu auacugcaaa gcuagauaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7203
<211>  1918
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7203
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acuauccuca cagcagucac uuucugcuuc      240

gccucaggac aaaacauaac cgaagaguuc uaccaaucca caugcuccgc cgucuccaaa      300

ggcuaccucu cagcgcuccg caccggcugg uacacauccg ucaucaccau cgaacuaagc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaaag uuaaacucau caagcaagaa      420

cucgacaaau acaaaaacgc agucacagaa cuucaaaugc ucaugugcuc cacacccgcc      480

acagguucug gcucagcaau cgcaagcggc gucgccguau gcaaaguccu ucaccucgaa      540

ggcgaaguca acaaaaucaa auccgcccuc cucuccacca auaaagcugu cgucucacuc      600

uccaacggcg ucagcguccu cacauucaaa guccucgacc ucaaaaacua cauagacaag      660

caacuccucc cgauacucaa caaacaaagc ugcucuaucu ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ucgucuccuc gaaaucaccc gcgaguucuc aguaaacgcc      780

ggggucacca caccagucuc caccuacaug cucaccaacu ccgaacuccu uagccucaua      840

aacgacaugc ccauaaccaa cgaccaaaag aaacucauga gcaacaacgu acaaauaguc      900

cgacaacaau ccuauuccau cauguguauc aucaaagaag aaguccucgc auacguaguc      960

caacuccccc uauacggcgu aaucgacacc ccauguugga aacuccacac cucaccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuca cccgcacaga ccgcggcugg     1080

uacugcgaca acgcgggcuc cgucagcuuc uuuccccaag cggaaaccug caaagucugc     1140

agcaacagag ucuucugcga cacuaugaac ucccucaccc uccccucaga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa ucaugaccag caaaacugac     1260

gucuccucgu ccgucaucac cucacucggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaacau ucagcaacgg cugcgacuac     1380

gucucgaaca aaggagucga caccguauca gugggcaaca cccuauacua cguaaacaag     1440

caagaaggca aaucacucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucucaag ucaacgagaa aaucaaccaa     1560

ucccuugccu ucauacguaa aagcgacgaa cuccuucaca acguaaacgc cgggaaaucc     1620

accacuaaca uaaugaucac caccaucauc aucguuauca uagucauccu ccucucucuc     1680

auagcagucg gccuacuccu guacugcaaa gcgcgcuaag gacuaguccc uguucccaga     1740

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1860

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1918


<210>  7204
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7204
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7205
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7205
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7206
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7206
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7207
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7207
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7208
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7208
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7209
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7209
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcugagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7210
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7210
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu caaagcaaac gcaauuacaa ccauacuaac cgcugucacc      180

uuuuguuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac augcuccgca      240

guaucuaaag gauaccucag cgcguuaaga acaggauggu acacaucggu aauaaccauc      300

gaauuaucca acauaaaaga aaauaaaugc aauggaacag acgcaaaagu caaauuaauu      360

aaacaagaac uagacaaaua uaaaaacgca guaaccgaau uacaaaugcu aauguguuca      420

acaccagcaa caggaucagg aucagcuaua gcuucaggag uugccguaug caaagugcua      480

cacuuagaag gagaagugaa uaaaauaaaa ucagcucuau uaucaacgaa caaagccgua      540

guaucucuau caaauggcgu aucaguacuc acauucaaag uacucgaccu aaaaaacuau      600

auagauaaac aacuauuacc cauccuaaau aaacaaagcu gcucuauauc aaacaucgaa      660

acaguaaugg aauuucaaca aaaaaacaac agacuacuag aaauaacccg agaguucuca      720

guuaaugcag gaguaacaac accagucuca acauacaugc ucacaaacuc agaacuccua      780

ucacuaauaa augacaugcc aauaacaaac gaccaaaaaa aacucauguc uaacaacguc      840

caaauaguaa gacaacaauc cuacagcaua auguguauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuacccuu auauggcgua auagauacac caugcuggaa acuccauacc      960

ucaccucuau guacaacaaa uaccaaagaa gguucuaaua uaugccuaac acgaacugac     1020

cgaggauggu acugugacaa cgcaggauca gucucuuucu uuccacaagc agaaaccugc     1080

aaaguaugca guaaccgcgu auuuugcgac acaaugaacu cccuaaccuu accaucagaa     1140

guaaacuuau guaacguaga cauauucaau ccaaaauaug acugcaaaau aaugacauca     1200

aaaacagacg uaagcucauc aguaauaacu ucacuaggcg caauuguauc augcuaugga     1260

aaaaccaaau guaccgcauc caacaaaaau aaaggaauaa uaaaaaccuu cucuaacgga     1320

ugcgacuacg uaucaaacaa agguguagau acaguuucug uaggaaacac acucuacuau     1380

guaaauaaac aagaaggaaa aucacuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccacuug uauuuccauc ugaugaauuu gaugcaagca uaucacaagu aaacgaaaaa     1500

auaaaccaau cucuagccuu uauacgaaaa agcgacgaau uacuacauaa cgucaacgcu     1560

ggaaaaucaa caacaaacau aaugauaaca acaauaauaa uaguaauaau agucauccua     1620

uuaucacuaa ucgccguagg acuacuccua uacugcaaag cuagauaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7211
<211>  1867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7211
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca cuauccucac agcagucacu      180

uucugcuucg ccucaggaca aaacauaacc gaagaguucu accaauccac augcuccgcc      240

gucuccaaag gcuaccucuc agcgcuccgc accggcuggu acacauccgu caucaccauc      300

gaacuaagca acauaaaaga aaacaaaugc aacggcaccg acgccaaagu uaaacucauc      360

aagcaagaac ucgacaaaua caaaaacgca gucacagaac uucaaaugcu caugugcucc      420

acacccgcca cagguucugg cucagcaauc gcaagcggcg ucgccguaug caaaguccuu      480

caccucgaag gcgaagucaa caaaaucaaa uccgcccucc ucuccaccaa uaaagcuguc      540

gucucacucu ccaacggcgu cagcguccuc acauucaaag uccucgaccu caaaaacuac      600

auagacaagc aacuccuccc gauacucaac aaacaaagcu gcucuaucuc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaau cgucuccucg aaaucacccg cgaguucuca      720

guaaacgccg gggucaccac accagucucc accuacaugc ucaccaacuc cgaacuccuu      780

agccucauaa acgacaugcc cauaaccaac gaccaaaaga aacucaugag caacaacgua      840

caaauagucc gacaacaauc cuauuccauc auguguauca ucaaagaaga aguccucgca      900

uacguagucc aacucccccu auacggcgua aucgacaccc cauguuggaa acuccacacc      960

ucaccacucu guaccaccaa caccaaagaa ggcucaaaca ucugccucac ccgcacagac     1020

cgcggcuggu acugcgacaa cgcgggcucc gucagcuucu uuccccaagc ggaaaccugc     1080

aaagucugca gcaacagagu cuucugcgac acuaugaacu cccucacccu ccccucagaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau caugaccagc     1200

aaaacugacg ucuccucguc cgucaucacc ucacucggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaacauu cagcaacggc     1320

ugcgacuacg ucucgaacaa aggagucgac accguaucag ugggcaacac ccuauacuac     1380

guaaacaagc aagaaggcaa aucacucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucucaagu caacgagaaa     1500

aucaaccaau cccuugccuu cauacguaaa agcgacgaac uccuucacaa cguaaacgcc     1560

gggaaaucca ccacuaacau aaugaucacc accaucauca ucguuaucau agucauccuc     1620

cucucucuca uagcagucgg ccuacuccug uacugcaaag cgcgcuaagg acuagucccu     1680

guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1860

cagaauu                                                               1867


<210>  7212
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7212
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7213
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7213
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7214
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7214
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7215
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7215
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7216
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7216
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7217
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7217
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cugaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7218
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7218
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccucaaa gcaaacgcaa uuacaaccau acuaaccgcu      120

gucaccuuuu guuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacaugc      180

uccgcaguau cuaaaggaua ccucagcgcg uuaagaacag gaugguacac aucgguaaua      240

accaucgaau uauccaacau aaaagaaaau aaaugcaaug gaacagacgc aaaagucaaa      300

uuaauuaaac aagaacuaga caaauauaaa aacgcaguaa ccgaauuaca aaugcuaaug      360

uguucaacac cagcaacagg aucaggauca gcuauagcuu caggaguugc cguaugcaaa      420

gugcuacacu uagaaggaga agugaauaaa auaaaaucag cucuauuauc aacgaacaaa      480

gccguaguau cucuaucaaa uggcguauca guacucacau ucaaaguacu cgaccuaaaa      540

aacuauauag auaaacaacu auuacccauc cuaaauaaac aaagcugcuc uauaucaaac      600

aucgaaacag uaauggaauu ucaacaaaaa aacaacagac uacuagaaau aacccgagag      660

uucucaguua augcaggagu aacaacacca gucucaacau acaugcucac aaacucagaa      720

cuccuaucac uaauaaauga caugccaaua acaaacgacc aaaaaaaacu caugucuaac      780

aacguccaaa uaguaagaca acaauccuac agcauaaugu guauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu acccuuauau ggcguaauag auacaccaug cuggaaacuc      900

cauaccucac cucuauguac aacaaauacc aaagaagguu cuaauauaug ccuaacacga      960

acugaccgag gaugguacug ugacaacgca ggaucagucu cuuucuuucc acaagcagaa     1020

accugcaaag uaugcaguaa ccgcguauuu ugcgacacaa ugaacucccu aaccuuacca     1080

ucagaaguaa acuuauguaa cguagacaua uucaauccaa aauaugacug caaaauaaug     1140

acaucaaaaa cagacguaag cucaucagua auaacuucac uaggcgcaau uguaucaugc     1200

uauggaaaaa ccaaauguac cgcauccaac aaaaauaaag gaauaauaaa aaccuucucu     1260

aacggaugcg acuacguauc aaacaaaggu guagauacag uuucuguagg aaacacacuc     1320

uacuauguaa auaaacaaga aggaaaauca cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cacuuguauu uccaucugau gaauuugaug caagcauauc acaaguaaac     1440

gaaaaaauaa accaaucucu agccuuuaua cgaaaaagcg acgaauuacu acauaacguc     1500

aacgcuggaa aaucaacaac aaacauaaug auaacaacaa uaauaauagu aauaauaguc     1560

auccuauuau cacuaaucgc cguaggacua cuccuauacu gcaaagcuag auaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7219
<211>  1813
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7219
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacuau ccucacagca      120

gucacuuucu gcuucgccuc aggacaaaac auaaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaaaggcua ccucucagcg cuccgcaccg gcugguacac auccgucauc      240

accaucgaac uaagcaacau aaaagaaaac aaaugcaacg gcaccgacgc caaaguuaaa      300

cucaucaagc aagaacucga caaauacaaa aacgcaguca cagaacuuca aaugcucaug      360

ugcuccacac ccgccacagg uucuggcuca gcaaucgcaa gcggcgucgc cguaugcaaa      420

guccuucacc ucgaaggcga agucaacaaa aucaaauccg cccuccucuc caccaauaaa      480

gcugucgucu cacucuccaa cggcgucagc guccucacau ucaaaguccu cgaccucaaa      540

aacuacauag acaagcaacu ccucccgaua cucaacaaac aaagcugcuc uaucuccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaucguc uccucgaaau cacccgcgag      660

uucucaguaa acgccggggu caccacacca gucuccaccu acaugcucac caacuccgaa      720

cuccuuagcc ucauaaacga caugcccaua accaacgacc aaaagaaacu caugagcaac      780

aacguacaaa uaguccgaca acaauccuau uccaucaugu guaucaucaa agaagaaguc      840

cucgcauacg uaguccaacu cccccuauac ggcguaaucg acaccccaug uuggaaacuc      900

cacaccucac cacucuguac caccaacacc aaagaaggcu caaacaucug ccucacccgc      960

acagaccgcg gcugguacug cgacaacgcg ggcuccguca gcuucuuucc ccaagcggaa     1020

accugcaaag ucugcagcaa cagagucuuc ugcgacacua ugaacucccu cacccucccc     1080

ucagaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaaucaug     1140

accagcaaaa cugacgucuc cucguccguc aucaccucac ucggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aacauucagc     1260

aacggcugcg acuacgucuc gaacaaagga gucgacaccg uaucaguggg caacacccua     1320

uacuacguaa acaagcaaga aggcaaauca cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ucaagucaac     1440

gagaaaauca accaaucccu ugccuucaua cguaaaagcg acgaacuccu ucacaacgua     1500

aacgccggga aauccaccac uaacauaaug aucaccacca ucaucaucgu uaucauaguc     1560

auccuccucu cucucauagc agucggccua cuccuguacu gcaaagcgcg cuaaggacua     1620

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1680

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1800

agccaccaga auu                                                        1813


<210>  7220
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7220
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      840

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug     1020

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1080

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1140

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1200

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1380

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1560

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1620

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1680

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1740

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7221
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7221
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      540

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      600

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      660

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      720

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      780

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      840

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      960

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg     1140

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1200

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1260

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1320

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1380

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1440

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1500

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1620

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1680

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1740

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7222
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7222
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      720

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      780

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      840

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      900

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      960

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc     1020

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1080

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1140

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1200

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1260

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1320

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1380

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1440

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1500

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1620

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1680

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1740

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7223
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7223
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      420

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      480

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      540

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      600

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      660

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      720

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      780

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      840

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      900

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      960

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua     1020

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca     1080

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc     1140

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1200

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1260

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1320

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1380

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1440

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1500

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1560

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1620

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1680

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1740

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7224
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7224
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      720

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      780

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      840

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      900

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      960

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug     1020

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1080

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1140

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1200

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1260

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1320

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1380

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1440

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1500

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1560

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1620

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1680

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1740

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7225
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7225
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      420

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      480

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      540

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      600

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      660

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      720

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      780

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      840

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      900

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      960

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug     1020

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu     1080

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga     1140

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1200

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1260

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1320

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1380

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1440

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1500

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1560

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1620

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1680

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1740

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu gaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7226
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7226
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaauuacuaa uccucaaagc aaacgcaauu acaaccauac uaaccgcugu caccuuuugu      300

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacaugcuc cgcaguaucu      360

aaaggauacc ucagcgcguu aagaacagga ugguacacau cgguaauaac caucgaauua      420

uccaacauaa aagaaaauaa augcaaugga acagacgcaa aagucaaauu aauuaaacaa      480

gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa ugcuaaugug uucaacacca      540

gcaacaggau caggaucagc uauagcuuca ggaguugccg uaugcaaagu gcuacacuua      600

gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa cgaacaaagc cguaguaucu      660

cuaucaaaug gcguaucagu acucacauuc aaaguacucg accuaaaaaa cuauauagau      720

aaacaacuau uacccauccu aaauaaacaa agcugcucua uaucaaacau cgaaacagua      780

auggaauuuc aacaaaaaaa caacagacua cuagaaauaa cccgagaguu cucaguuaau      840

gcaggaguaa caacaccagu cucaacauac augcucacaa acucagaacu ccuaucacua      900

auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca ugucuaacaa cguccaaaua      960

guaagacaac aauccuacag cauaaugugu auaauaaaag aagaaguuuu agcauacguc     1020

guacaacuac ccuuauaugg cguaauagau acaccaugcu ggaaacucca uaccucaccu     1080

cuauguacaa caaauaccaa agaagguucu aauauaugcc uaacacgaac ugaccgagga     1140

ugguacugug acaacgcagg aucagucucu uucuuuccac aagcagaaac cugcaaagua     1200

ugcaguaacc gcguauuuug cgacacaaug aacucccuaa ccuuaccauc agaaguaaac     1260

uuauguaacg uagacauauu caauccaaaa uaugacugca aaauaaugac aucaaaaaca     1320

gacguaagcu caucaguaau aacuucacua ggcgcaauug uaucaugcua uggaaaaacc     1380

aaauguaccg cauccaacaa aaauaaagga auaauaaaaa ccuucucuaa cggaugcgac     1440

uacguaucaa acaaaggugu agauacaguu ucuguaggaa acacacucua cuauguaaau     1500

aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1560

cuuguauuuc caucugauga auuugaugca agcauaucac aaguaaacga aaaaauaaac     1620

caaucucuag ccuuuauacg aaaaagcgac gaauuacuac auaacgucaa cgcuggaaaa     1680

ucaacaacaa acauaaugau aacaacaaua auaauaguaa uaauagucau ccuauuauca     1740

cuaaucgccg uaggacuacu ccuauacugc aaagcuagau aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7227
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7227
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccucaaagc caacgccaua accacuaucc ucacagcagu cacuuucugc      300

uucgccucag gacaaaacau aaccgaagag uucuaccaau ccacaugcuc cgccgucucc      360

aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau ccgucaucac caucgaacua      420

agcaacauaa aagaaaacaa augcaacggc accgacgcca aaguuaaacu caucaagcaa      480

gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa ugcucaugug cuccacaccc      540

gccacagguu cuggcucagc aaucgcaagc ggcgucgccg uaugcaaagu ccuucaccuc      600

gaaggcgaag ucaacaaaau caaauccgcc cuccucucca ccaauaaagc ugucgucuca      660

cucuccaacg gcgucagcgu ccucacauuc aaaguccucg accucaaaaa cuacauagac      720

aagcaacucc ucccgauacu caacaaacaa agcugcucua ucuccaacau cgaaaccguc      780

auggaguucc aacagaaaaa caaucgucuc cucgaaauca cccgcgaguu cucaguaaac      840

gccgggguca ccacaccagu cuccaccuac augcucacca acuccgaacu ccuuagccuc      900

auaaacgaca ugcccauaac caacgaccaa aagaaacuca ugagcaacaa cguacaaaua      960

guccgacaac aauccuauuc caucaugugu aucaucaaag aagaaguccu cgcauacgua     1020

guccaacucc cccuauacgg cguaaucgac accccauguu ggaaacucca caccucacca     1080

cucuguacca ccaacaccaa agaaggcuca aacaucugcc ucacccgcac agaccgcggc     1140

ugguacugcg acaacgcggg cuccgucagc uucuuucccc aagcggaaac cugcaaaguc     1200

ugcagcaaca gagucuucug cgacacuaug aacucccuca cccuccccuc agaagucaac     1260

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaaucaugac cagcaaaacu     1320

gacgucuccu cguccgucau caccucacuc ggcgcaaucg ugagcugcua cggcaaaacc     1380

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa cauucagcaa cggcugcgac     1440

uacgucucga acaaaggagu cgacaccgua ucagugggca acacccuaua cuacguaaac     1500

aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1560

cucgucuucc ccuccgacga guucgacgcc uccaucucuc aagucaacga gaaaaucaac     1620

caaucccuug ccuucauacg uaaaagcgac gaacuccuuc acaacguaaa cgccgggaaa     1680

uccaccacua acauaaugau caccaccauc aucaucguua ucauagucau ccuccucucu     1740

cucauagcag ucggccuacu ccuguacugc aaagcgcgcu aaggacuagu guccaccugu     1800

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7228
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7228
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7229
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7229
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      480

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1320

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7230
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7230
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7231
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7231
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      420

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      480

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      540

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      720

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      780

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua      840

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca      900

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc      960

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1020

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1080

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1140

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1200

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1260

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1320

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1380

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1440

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1500

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1560

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7232
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7232
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7233
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7233
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      420

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      480

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      540

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      720

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      780

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug      840

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu      900

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga      960

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1020

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1080

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1140

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1260

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1380

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1440

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1500

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1560

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu gaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7234
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7234
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaauuacuaa uccucaaagc aaacgcaauu acaaccauac uaaccgcugu caccuuuugu      120

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacaugcuc cgcaguaucu      180

aaaggauacc ucagcgcguu aagaacagga ugguacacau cgguaauaac caucgaauua      240

uccaacauaa aagaaaauaa augcaaugga acagacgcaa aagucaaauu aauuaaacaa      300

gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa ugcuaaugug uucaacacca      360

gcaacaggau caggaucagc uauagcuuca ggaguugccg uaugcaaagu gcuacacuua      420

gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa cgaacaaagc cguaguaucu      480

cuaucaaaug gcguaucagu acucacauuc aaaguacucg accuaaaaaa cuauauagau      540

aaacaacuau uacccauccu aaauaaacaa agcugcucua uaucaaacau cgaaacagua      600

auggaauuuc aacaaaaaaa caacagacua cuagaaauaa cccgagaguu cucaguuaau      660

gcaggaguaa caacaccagu cucaacauac augcucacaa acucagaacu ccuaucacua      720

auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca ugucuaacaa cguccaaaua      780

guaagacaac aauccuacag cauaaugugu auaauaaaag aagaaguuuu agcauacguc      840

guacaacuac ccuuauaugg cguaauagau acaccaugcu ggaaacucca uaccucaccu      900

cuauguacaa caaauaccaa agaagguucu aauauaugcc uaacacgaac ugaccgagga      960

ugguacugug acaacgcagg aucagucucu uucuuuccac aagcagaaac cugcaaagua     1020

ugcaguaacc gcguauuuug cgacacaaug aacucccuaa ccuuaccauc agaaguaaac     1080

uuauguaacg uagacauauu caauccaaaa uaugacugca aaauaaugac aucaaaaaca     1140

gacguaagcu caucaguaau aacuucacua ggcgcaauug uaucaugcua uggaaaaacc     1200

aaauguaccg cauccaacaa aaauaaagga auaauaaaaa ccuucucuaa cggaugcgac     1260

uacguaucaa acaaaggugu agauacaguu ucuguaggaa acacacucua cuauguaaau     1320

aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1380

cuuguauuuc caucugauga auuugaugca agcauaucac aaguaaacga aaaaauaaac     1440

caaucucuag ccuuuauacg aaaaagcgac gaauuacuac auaacgucaa cgcuggaaaa     1500

ucaacaacaa acauaaugau aacaacaaua auaauaguaa uaauagucau ccuauuauca     1560

cuaaucgccg uaggacuacu ccuauacugc aaagcuagau aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7235
<211>  1814
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7235
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgccaua accacuaucc ucacagcagu cacuuucugc      120

uucgccucag gacaaaacau aaccgaagag uucuaccaau ccacaugcuc cgccgucucc      180

aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau ccgucaucac caucgaacua      240

agcaacauaa aagaaaacaa augcaacggc accgacgcca aaguuaaacu caucaagcaa      300

gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa ugcucaugug cuccacaccc      360

gccacagguu cuggcucagc aaucgcaagc ggcgucgccg uaugcaaagu ccuucaccuc      420

gaaggcgaag ucaacaaaau caaauccgcc cuccucucca ccaauaaagc ugucgucuca      480

cucuccaacg gcgucagcgu ccucacauuc aaaguccucg accucaaaaa cuacauagac      540

aagcaacucc ucccgauacu caacaaacaa agcugcucua ucuccaacau cgaaaccguc      600

auggaguucc aacagaaaaa caaucgucuc cucgaaauca cccgcgaguu cucaguaaac      660

gccgggguca ccacaccagu cuccaccuac augcucacca acuccgaacu ccuuagccuc      720

auaaacgaca ugcccauaac caacgaccaa aagaaacuca ugagcaacaa cguacaaaua      780

guccgacaac aauccuauuc caucaugugu aucaucaaag aagaaguccu cgcauacgua      840

guccaacucc cccuauacgg cguaaucgac accccauguu ggaaacucca caccucacca      900

cucuguacca ccaacaccaa agaaggcuca aacaucugcc ucacccgcac agaccgcggc      960

ugguacugcg acaacgcggg cuccgucagc uucuuucccc aagcggaaac cugcaaaguc     1020

ugcagcaaca gagucuucug cgacacuaug aacucccuca cccuccccuc agaagucaac     1080

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaaucaugac cagcaaaacu     1140

gacgucuccu cguccgucau caccucacuc ggcgcaaucg ugagcugcua cggcaaaacc     1200

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa cauucagcaa cggcugcgac     1260

uacgucucga acaaaggagu cgacaccgua ucagugggca acacccuaua cuacguaaac     1320

aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucucuc aagucaacga gaaaaucaac     1440

caaucccuug ccuucauacg uaaaagcgac gaacuccuuc acaacguaaa cgccgggaaa     1500

uccaccacua acauaaugau caccaccauc aucaucguua ucauagucau ccuccucucu     1560

cucauagcag ucggccuacu ccuguacugc aaagcgcgcu aaggacuagu guccaccugu     1620

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1680

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1800

gagccaccag aauu                                                       1814


<210>  7236
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7236
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7237
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7237
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7238
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7238
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7239
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7239
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7240
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7240
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7241
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7241
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7242
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7242
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccucaaagc aaacgcaauu acaaccauac      120

uaaccgcugu caccuuuugu uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacaugcuc cgcaguaucu aaaggauacc ucagcgcguu aagaacagga ugguacacau      240

cgguaauaac caucgaauua uccaacauaa aagaaaauaa augcaaugga acagacgcaa      300

aagucaaauu aauuaaacaa gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa      360

ugcuaaugug uucaacacca gcaacaggau caggaucagc uauagcuuca ggaguugccg      420

uaugcaaagu gcuacacuua gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa      480

cgaacaaagc cguaguaucu cuaucaaaug gcguaucagu acucacauuc aaaguacucg      540

accuaaaaaa cuauauagau aaacaacuau uacccauccu aaauaaacaa agcugcucua      600

uaucaaacau cgaaacagua auggaauuuc aacaaaaaaa caacagacua cuagaaauaa      660

cccgagaguu cucaguuaau gcaggaguaa caacaccagu cucaacauac augcucacaa      720

acucagaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa cguccaaaua guaagacaac aauccuacag cauaaugugu auaauaaaag      840

aagaaguuuu agcauacguc guacaacuac ccuuauaugg cguaauagau acaccaugcu      900

ggaaacucca uaccucaccu cuauguacaa caaauaccaa agaagguucu aauauaugcc      960

uaacacgaac ugaccgagga ugguacugug acaacgcagg aucagucucu uucuuuccac     1020

aagcagaaac cugcaaagua ugcaguaacc gcguauuuug cgacacaaug aacucccuaa     1080

ccuuaccauc agaaguaaac uuauguaacg uagacauauu caauccaaaa uaugacugca     1140

aaauaaugac aucaaaaaca gacguaagcu caucaguaau aacuucacua ggcgcaauug     1200

uaucaugcua uggaaaaacc aaauguaccg cauccaacaa aaauaaagga auaauaaaaa     1260

ccuucucuaa cggaugcgac uacguaucaa acaaaggugu agauacaguu ucuguaggaa     1320

acacacucua cuauguaaau aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca cuuguauuuc caucugauga auuugaugca agcauaucac     1440

aaguaaacga aaaaauaaac caaucucuag ccuuuauacg aaaaagcgac gaauuacuac     1500

auaacgucaa cgcuggaaaa ucaacaacaa acauaaugau aacaacaaua auaauaguaa     1560

uaauagucau ccuauuauca cuaaucgccg uaggacuacu ccuauacugc aaagcuagau     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7243
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7243
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacuaucc      120

ucacagcagu cacuuucugc uucgccucag gacaaaacau aaccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau      240

ccgucaucac caucgaacua agcaacauaa aagaaaacaa augcaacggc accgacgcca      300

aaguuaaacu caucaagcaa gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa      360

ugcucaugug cuccacaccc gccacagguu cuggcucagc aaucgcaagc ggcgucgccg      420

uaugcaaagu ccuucaccuc gaaggcgaag ucaacaaaau caaauccgcc cuccucucca      480

ccaauaaagc ugucgucuca cucuccaacg gcgucagcgu ccucacauuc aaaguccucg      540

accucaaaaa cuacauagac aagcaacucc ucccgauacu caacaaacaa agcugcucua      600

ucuccaacau cgaaaccguc auggaguucc aacagaaaaa caaucgucuc cucgaaauca      660

cccgcgaguu cucaguaaac gccgggguca ccacaccagu cuccaccuac augcucacca      720

acuccgaacu ccuuagccuc auaaacgaca ugcccauaac caacgaccaa aagaaacuca      780

ugagcaacaa cguacaaaua guccgacaac aauccuauuc caucaugugu aucaucaaag      840

aagaaguccu cgcauacgua guccaacucc cccuauacgg cguaaucgac accccauguu      900

ggaaacucca caccucacca cucuguacca ccaacaccaa agaaggcuca aacaucugcc      960

ucacccgcac agaccgcggc ugguacugcg acaacgcggg cuccgucagc uucuuucccc     1020

aagcggaaac cugcaaaguc ugcagcaaca gagucuucug cgacacuaug aacucccuca     1080

cccuccccuc agaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaaucaugac cagcaaaacu gacgucuccu cguccgucau caccucacuc ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

cauucagcaa cggcugcgac uacgucucga acaaaggagu cgacaccgua ucagugggca     1320

acacccuaua cuacguaaac aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucucuc     1440

aagucaacga gaaaaucaac caaucccuug ccuucauacg uaaaagcgac gaacuccuuc     1500

acaacguaaa cgccgggaaa uccaccacua acauaaugau caccaccauc aucaucguua     1560

ucauagucau ccuccucucu cucauagcag ucggccuacu ccuguacugc aaagcgcgcu     1620

aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau     1680

aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7244
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7244
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7245
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7245
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7246
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7246
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7247
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7247
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7248
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7248
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7249
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7249
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7250
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7250
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccucaaagc aaacgcaauu acaaccauac      120

uaaccgcugu caccuuuugu uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacaugcuc cgcaguaucu aaaggauacc ucagcgcguu aagaacagga ugguacacau      240

cgguaauaac caucgaauua uccaacauaa aagaaaauaa augcaaugga acagacgcaa      300

aagucaaauu aauuaaacaa gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa      360

ugcuaaugug uucaacacca gcaacaggau caggaucagc uauagcuuca ggaguugccg      420

uaugcaaagu gcuacacuua gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa      480

cgaacaaagc cguaguaucu cuaucaaaug gcguaucagu acucacauuc aaaguacucg      540

accuaaaaaa cuauauagau aaacaacuau uacccauccu aaauaaacaa agcugcucua      600

uaucaaacau cgaaacagua auggaauuuc aacaaaaaaa caacagacua cuagaaauaa      660

cccgagaguu cucaguuaau gcaggaguaa caacaccagu cucaacauac augcucacaa      720

acucagaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa cguccaaaua guaagacaac aauccuacag cauaaugugu auaauaaaag      840

aagaaguuuu agcauacguc guacaacuac ccuuauaugg cguaauagau acaccaugcu      900

ggaaacucca uaccucaccu cuauguacaa caaauaccaa agaagguucu aauauaugcc      960

uaacacgaac ugaccgagga ugguacugug acaacgcagg aucagucucu uucuuuccac     1020

aagcagaaac cugcaaagua ugcaguaacc gcguauuuug cgacacaaug aacucccuaa     1080

ccuuaccauc agaaguaaac uuauguaacg uagacauauu caauccaaaa uaugacugca     1140

aaauaaugac aucaaaaaca gacguaagcu caucaguaau aacuucacua ggcgcaauug     1200

uaucaugcua uggaaaaacc aaauguaccg cauccaacaa aaauaaagga auaauaaaaa     1260

ccuucucuaa cggaugcgac uacguaucaa acaaaggugu agauacaguu ucuguaggaa     1320

acacacucua cuauguaaau aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca cuuguauuuc caucugauga auuugaugca agcauaucac     1440

aaguaaacga aaaaauaaac caaucucuag ccuuuauacg aaaaagcgac gaauuacuac     1500

auaacgucaa cgcuggaaaa ucaacaacaa acauaaugau aacaacaaua auaauaguaa     1560

uaauagucau ccuauuauca cuaaucgccg uaggacuacu ccuauacugc aaagcuagau     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7251
<211>  1885
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7251
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacuaucc      120

ucacagcagu cacuuucugc uucgccucag gacaaaacau aaccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau      240

ccgucaucac caucgaacua agcaacauaa aagaaaacaa augcaacggc accgacgcca      300

aaguuaaacu caucaagcaa gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa      360

ugcucaugug cuccacaccc gccacagguu cuggcucagc aaucgcaagc ggcgucgccg      420

uaugcaaagu ccuucaccuc gaaggcgaag ucaacaaaau caaauccgcc cuccucucca      480

ccaauaaagc ugucgucuca cucuccaacg gcgucagcgu ccucacauuc aaaguccucg      540

accucaaaaa cuacauagac aagcaacucc ucccgauacu caacaaacaa agcugcucua      600

ucuccaacau cgaaaccguc auggaguucc aacagaaaaa caaucgucuc cucgaaauca      660

cccgcgaguu cucaguaaac gccgggguca ccacaccagu cuccaccuac augcucacca      720

acuccgaacu ccuuagccuc auaaacgaca ugcccauaac caacgaccaa aagaaacuca      780

ugagcaacaa cguacaaaua guccgacaac aauccuauuc caucaugugu aucaucaaag      840

aagaaguccu cgcauacgua guccaacucc cccuauacgg cguaaucgac accccauguu      900

ggaaacucca caccucacca cucuguacca ccaacaccaa agaaggcuca aacaucugcc      960

ucacccgcac agaccgcggc ugguacugcg acaacgcggg cuccgucagc uucuuucccc     1020

aagcggaaac cugcaaaguc ugcagcaaca gagucuucug cgacacuaug aacucccuca     1080

cccuccccuc agaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaaucaugac cagcaaaacu gacgucuccu cguccgucau caccucacuc ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

cauucagcaa cggcugcgac uacgucucga acaaaggagu cgacaccgua ucagugggca     1320

acacccuaua cuacguaaac aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucucuc     1440

aagucaacga gaaaaucaac caaucccuug ccuucauacg uaaaagcgac gaacuccuuc     1500

acaacguaaa cgccgggaaa uccaccacua acauaaugau caccaccauc aucaucguua     1560

ucauagucau ccuccucucu cucauagcag ucggccuacu ccuguacugc aaagcgcgcu     1620

aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa gagauccuuc     1680

uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau aauaaaucug     1740

guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1860

ggcucuuuuc agagccacca gaauu                                           1885


<210>  7252
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7252
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7253
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7253
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7254
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7254
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7255
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7255
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7256
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7256
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7257
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7257
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcugagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7258
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7258
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu caaagcaaac gcaauuacaa ccauacuaac cgcugucacc      180

uuuuguuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac augcuccgca      240

guaucuaaag gauaccucag cgcguuaaga acaggauggu acacaucggu aauaaccauc      300

gaauuaucca acauaaaaga aaauaaaugc aauggaacag acgcaaaagu caaauuaauu      360

aaacaagaac uagacaaaua uaaaaacgca guaaccgaau uacaaaugcu aauguguuca      420

acaccagcaa caggaucagg aucagcuaua gcuucaggag uugccguaug caaagugcua      480

cacuuagaag gagaagugaa uaaaauaaaa ucagcucuau uaucaacgaa caaagccgua      540

guaucucuau caaauggcgu aucaguacuc acauucaaag uacucgaccu aaaaaacuau      600

auagauaaac aacuauuacc cauccuaaau aaacaaagcu gcucuauauc aaacaucgaa      660

acaguaaugg aauuucaaca aaaaaacaac agacuacuag aaauaacccg agaguucuca      720

guuaaugcag gaguaacaac accagucuca acauacaugc ucacaaacuc agaacuccua      780

ucacuaauaa augacaugcc aauaacaaac gaccaaaaaa aacucauguc uaacaacguc      840

caaauaguaa gacaacaauc cuacagcaua auguguauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuacccuu auauggcgua auagauacac caugcuggaa acuccauacc      960

ucaccucuau guacaacaaa uaccaaagaa gguucuaaua uaugccuaac acgaacugac     1020

cgaggauggu acugugacaa cgcaggauca gucucuuucu uuccacaagc agaaaccugc     1080

aaaguaugca guaaccgcgu auuuugcgac acaaugaacu cccuaaccuu accaucagaa     1140

guaaacuuau guaacguaga cauauucaau ccaaaauaug acugcaaaau aaugacauca     1200

aaaacagacg uaagcucauc aguaauaacu ucacuaggcg caauuguauc augcuaugga     1260

aaaaccaaau guaccgcauc caacaaaaau aaaggaauaa uaaaaaccuu cucuaacgga     1320

ugcgacuacg uaucaaacaa agguguagau acaguuucug uaggaaacac acucuacuau     1380

guaaauaaac aagaaggaaa aucacuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccacuug uauuuccauc ugaugaauuu gaugcaagca uaucacaagu aaacgaaaaa     1500

auaaaccaau cucuagccuu uauacgaaaa agcgacgaau uacuacauaa cgucaacgcu     1560

ggaaaaucaa caacaaacau aaugauaaca acaauaauaa uaguaauaau agucauccua     1620

uuaucacuaa ucgccguagg acuacuccua uacugcaaag cuagauaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7259
<211>  1947
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7259
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca cuauccucac agcagucacu      180

uucugcuucg ccucaggaca aaacauaacc gaagaguucu accaauccac augcuccgcc      240

gucuccaaag gcuaccucuc agcgcuccgc accggcuggu acacauccgu caucaccauc      300

gaacuaagca acauaaaaga aaacaaaugc aacggcaccg acgccaaagu uaaacucauc      360

aagcaagaac ucgacaaaua caaaaacgca gucacagaac uucaaaugcu caugugcucc      420

acacccgcca cagguucugg cucagcaauc gcaagcggcg ucgccguaug caaaguccuu      480

caccucgaag gcgaagucaa caaaaucaaa uccgcccucc ucuccaccaa uaaagcuguc      540

gucucacucu ccaacggcgu cagcguccuc acauucaaag uccucgaccu caaaaacuac      600

auagacaagc aacuccuccc gauacucaac aaacaaagcu gcucuaucuc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaau cgucuccucg aaaucacccg cgaguucuca      720

guaaacgccg gggucaccac accagucucc accuacaugc ucaccaacuc cgaacuccuu      780

agccucauaa acgacaugcc cauaaccaac gaccaaaaga aacucaugag caacaacgua      840

caaauagucc gacaacaauc cuauuccauc auguguauca ucaaagaaga aguccucgca      900

uacguagucc aacucccccu auacggcgua aucgacaccc cauguuggaa acuccacacc      960

ucaccacucu guaccaccaa caccaaagaa ggcucaaaca ucugccucac ccgcacagac     1020

cgcggcuggu acugcgacaa cgcgggcucc gucagcuucu uuccccaagc ggaaaccugc     1080

aaagucugca gcaacagagu cuucugcgac acuaugaacu cccucacccu ccccucagaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau caugaccagc     1200

aaaacugacg ucuccucguc cgucaucacc ucacucggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaacauu cagcaacggc     1320

ugcgacuacg ucucgaacaa aggagucgac accguaucag ugggcaacac ccuauacuac     1380

guaaacaagc aagaaggcaa aucacucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucucaagu caacgagaaa     1500

aucaaccaau cccuugccuu cauacguaaa agcgacgaac uccuucacaa cguaaacgcc     1560

gggaaaucca ccacuaacau aaugaucacc accaucauca ucguuaucau agucauccuc     1620

cucucucuca uagcagucgg ccuacuccug uacugcaaag cgcgcuaagg acuaguacug     1680

gcugcaucuc ccuuuccucu guccuccauc cuucucccag gauggugaag ggggaccugg     1740

uacccaguga uccccacccc aggauccuaa aucaugacuu accugcuaau aaaaacucau     1800

uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1920

aaggcucuuu ucagagccac cagaauu                                         1947


<210>  7260
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7260
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7261
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7261
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7262
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7262
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7263
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7263
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacggug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7264
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7264
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7265
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7265
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7266
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7266
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccucaaagca      120

aacgcaauua caaccauacu aaccgcuguc accuuuuguu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacaugcucc gcaguaucua aaggauaccu cagcgcguua      240

agaacaggau gguacacauc gguaauaacc aucgaauuau ccaacauaaa agaaaauaaa      300

ugcaauggaa cagacgcaaa agucaaauua auuaaacaag aacuagacaa auauaaaaac      360

gcaguaaccg aauuacaaau gcuaaugugu ucaacaccag caacaggauc aggaucagcu      420

auagcuucag gaguugccgu augcaaagug cuacacuuag aaggagaagu gaauaaaaua      480

aaaucagcuc uauuaucaac gaacaaagcc guaguaucuc uaucaaaugg cguaucagua      540

cucacauuca aaguacucga ccuaaaaaac uauauagaua aacaacuauu acccauccua      600

aauaaacaaa gcugcucuau aucaaacauc gaaacaguaa uggaauuuca acaaaaaaac      660

aacagacuac uagaaauaac ccgagaguuc ucaguuaaug caggaguaac aacaccaguc      720

ucaacauaca ugcucacaaa cucagaacuc cuaucacuaa uaaaugacau gccaauaaca      780

aacgaccaaa aaaaacucau gucuaacaac guccaaauag uaagacaaca auccuacagc      840

auaaugugua uaauaaaaga agaaguuuua gcauacgucg uacaacuacc cuuauauggc      900

guaauagaua caccaugcug gaaacuccau accucaccuc uauguacaac aaauaccaaa      960

gaagguucua auauaugccu aacacgaacu gaccgaggau gguacuguga caacgcagga     1020

ucagucucuu ucuuuccaca agcagaaacc ugcaaaguau gcaguaaccg cguauuuugc     1080

gacacaauga acucccuaac cuuaccauca gaaguaaacu uauguaacgu agacauauuc     1140

aauccaaaau augacugcaa aauaaugaca ucaaaaacag acguaagcuc aucaguaaua     1200

acuucacuag gcgcaauugu aucaugcuau ggaaaaacca aauguaccgc auccaacaaa     1260

aauaaaggaa uaauaaaaac cuucucuaac ggaugcgacu acguaucaaa caaaggugua     1320

gauacaguuu cuguaggaaa cacacucuac uauguaaaua aacaagaagg aaaaucacua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccac uuguauuucc aucugaugaa     1440

uuugaugcaa gcauaucaca aguaaacgaa aaaauaaacc aaucucuagc cuuuauacga     1500

aaaagcgacg aauuacuaca uaacgucaac gcuggaaaau caacaacaaa cauaaugaua     1560

acaacaauaa uaauaguaau aauagucauc cuauuaucac uaaucgccgu aggacuacuc     1620

cuauacugca aagcuagaua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7267
<211>  1853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7267
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacuauccu cacagcaguc acuuucugcu ucgccucagg acaaaacaua      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca aaggcuaccu cucagcgcuc      240

cgcaccggcu gguacacauc cgucaucacc aucgaacuaa gcaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa aguuaaacuc aucaagcaag aacucgacaa auacaaaaac      360

gcagucacag aacuucaaau gcucaugugc uccacacccg ccacagguuc uggcucagca      420

aucgcaagcg gcgucgccgu augcaaaguc cuucaccucg aaggcgaagu caacaaaauc      480

aaauccgccc uccucuccac caauaaagcu gucgucucac ucuccaacgg cgucagcguc      540

cucacauuca aaguccucga ccucaaaaac uacauagaca agcaacuccu cccgauacuc      600

aacaaacaaa gcugcucuau cuccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaucgucucc ucgaaaucac ccgcgaguuc ucaguaaacg ccggggucac cacaccaguc      720

uccaccuaca ugcucaccaa cuccgaacuc cuuagccuca uaaacgacau gcccauaacc      780

aacgaccaaa agaaacucau gagcaacaac guacaaauag uccgacaaca auccuauucc      840

aucaugugua ucaucaaaga agaaguccuc gcauacguag uccaacuccc ccuauacggc      900

guaaucgaca ccccauguug gaaacuccac accucaccac ucuguaccac caacaccaaa      960

gaaggcucaa acaucugccu cacccgcaca gaccgcggcu gguacugcga caacgcgggc     1020

uccgucagcu ucuuucccca agcggaaacc ugcaaagucu gcagcaacag agucuucugc     1080

gacacuauga acucccucac ccuccccuca gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aaucaugacc agcaaaacug acgucuccuc guccgucauc     1200

accucacucg gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac auucagcaac ggcugcgacu acgucucgaa caaaggaguc     1320

gacaccguau cagugggcaa cacccuauac uacguaaaca agcaagaagg caaaucacuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucucuca agucaacgag aaaaucaacc aaucccuugc cuucauacgu     1500

aaaagcgacg aacuccuuca caacguaaac gccgggaaau ccaccacuaa cauaaugauc     1560

accaccauca ucaucguuau cauagucauc cuccucucuc ucauagcagu cggccuacuc     1620

cuguacugca aagcgcgcua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1680

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1800

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1853


<210>  7268
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7268
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7269
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7269
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7270
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7270
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7271
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7271
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7272
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7272
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7273
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7273
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcugagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7274
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7274
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu caaagcaaac gcaauuacaa ccauacuaac cgcugucacc      180

uuuuguuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac augcuccgca      240

guaucuaaag gauaccucag cgcguuaaga acaggauggu acacaucggu aauaaccauc      300

gaauuaucca acauaaaaga aaauaaaugc aauggaacag acgcaaaagu caaauuaauu      360

aaacaagaac uagacaaaua uaaaaacgca guaaccgaau uacaaaugcu aauguguuca      420

acaccagcaa caggaucagg aucagcuaua gcuucaggag uugccguaug caaagugcua      480

cacuuagaag gagaagugaa uaaaauaaaa ucagcucuau uaucaacgaa caaagccgua      540

guaucucuau caaauggcgu aucaguacuc acauucaaag uacucgaccu aaaaaacuau      600

auagauaaac aacuauuacc cauccuaaau aaacaaagcu gcucuauauc aaacaucgaa      660

acaguaaugg aauuucaaca aaaaaacaac agacuacuag aaauaacccg agaguucuca      720

guuaaugcag gaguaacaac accagucuca acauacaugc ucacaaacuc agaacuccua      780

ucacuaauaa augacaugcc aauaacaaac gaccaaaaaa aacucauguc uaacaacguc      840

caaauaguaa gacaacaauc cuacagcaua auguguauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuacccuu auauggcgua auagauacac caugcuggaa acuccauacc      960

ucaccucuau guacaacaaa uaccaaagaa gguucuaaua uaugccuaac acgaacugac     1020

cgaggauggu acugugacaa cgcaggauca gucucuuucu uuccacaagc agaaaccugc     1080

aaaguaugca guaaccgcgu auuuugcgac acaaugaacu cccuaaccuu accaucagaa     1140

guaaacuuau guaacguaga cauauucaau ccaaaauaug acugcaaaau aaugacauca     1200

aaaacagacg uaagcucauc aguaauaacu ucacuaggcg caauuguauc augcuaugga     1260

aaaaccaaau guaccgcauc caacaaaaau aaaggaauaa uaaaaaccuu cucuaacgga     1320

ugcgacuacg uaucaaacaa agguguagau acaguuucug uaggaaacac acucuacuau     1380

guaaauaaac aagaaggaaa aucacuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccacuug uauuuccauc ugaugaauuu gaugcaagca uaucacaagu aaacgaaaaa     1500

auaaaccaau cucuagccuu uauacgaaaa agcgacgaau uacuacauaa cgucaacgcu     1560

ggaaaaucaa caacaaacau aaugauaaca acaauaauaa uaguaauaau agucauccua     1620

uuaucacuaa ucgccguagg acuacuccua uacugcaaag cuagauaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7275
<211>  1943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7275
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca cuauccucac agcagucacu      180

uucugcuucg ccucaggaca aaacauaacc gaagaguucu accaauccac augcuccgcc      240

gucuccaaag gcuaccucuc agcgcuccgc accggcuggu acacauccgu caucaccauc      300

gaacuaagca acauaaaaga aaacaaaugc aacggcaccg acgccaaagu uaaacucauc      360

aagcaagaac ucgacaaaua caaaaacgca gucacagaac uucaaaugcu caugugcucc      420

acacccgcca cagguucugg cucagcaauc gcaagcggcg ucgccguaug caaaguccuu      480

caccucgaag gcgaagucaa caaaaucaaa uccgcccucc ucuccaccaa uaaagcuguc      540

gucucacucu ccaacggcgu cagcguccuc acauucaaag uccucgaccu caaaaacuac      600

auagacaagc aacuccuccc gauacucaac aaacaaagcu gcucuaucuc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaau cgucuccucg aaaucacccg cgaguucuca      720

guaaacgccg gggucaccac accagucucc accuacaugc ucaccaacuc cgaacuccuu      780

agccucauaa acgacaugcc cauaaccaac gaccaaaaga aacucaugag caacaacgua      840

caaauagucc gacaacaauc cuauuccauc auguguauca ucaaagaaga aguccucgca      900

uacguagucc aacucccccu auacggcgua aucgacaccc cauguuggaa acuccacacc      960

ucaccacucu guaccaccaa caccaaagaa ggcucaaaca ucugccucac ccgcacagac     1020

cgcggcuggu acugcgacaa cgcgggcucc gucagcuucu uuccccaagc ggaaaccugc     1080

aaagucugca gcaacagagu cuucugcgac acuaugaacu cccucacccu ccccucagaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau caugaccagc     1200

aaaacugacg ucuccucguc cgucaucacc ucacucggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaacauu cagcaacggc     1320

ugcgacuacg ucucgaacaa aggagucgac accguaucag ugggcaacac ccuauacuac     1380

guaaacaagc aagaaggcaa aucacucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucucaagu caacgagaaa     1500

aucaaccaau cccuugccuu cauacguaaa agcgacgaac uccuucacaa cguaaacgcc     1560

gggaaaucca ccacuaacau aaugaucacc accaucauca ucguuaucau agucauccuc     1620

cucucucuca uagcagucgg ccuacuccug uacugcaaag cgcgcuaagg acuaguggaa     1680

gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg ucaucuguuc cuguuagaag     1740

gcuaugcagc auauuauaua cuaugcgcau guuaugaaau gcauaauaaa aaauuuuaaa     1800

aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1920

cucuuuucag agccaccaga auu                                             1943


<210>  7276
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7276
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7277
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7277
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7278
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7278
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7279
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7279
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacggug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7280
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7280
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7281
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7281
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7282
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7282
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccucaaagca      120

aacgcaauua caaccauacu aaccgcuguc accuuuuguu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacaugcucc gcaguaucua aaggauaccu cagcgcguua      240

agaacaggau gguacacauc gguaauaacc aucgaauuau ccaacauaaa agaaaauaaa      300

ugcaauggaa cagacgcaaa agucaaauua auuaaacaag aacuagacaa auauaaaaac      360

gcaguaaccg aauuacaaau gcuaaugugu ucaacaccag caacaggauc aggaucagcu      420

auagcuucag gaguugccgu augcaaagug cuacacuuag aaggagaagu gaauaaaaua      480

aaaucagcuc uauuaucaac gaacaaagcc guaguaucuc uaucaaaugg cguaucagua      540

cucacauuca aaguacucga ccuaaaaaac uauauagaua aacaacuauu acccauccua      600

aauaaacaaa gcugcucuau aucaaacauc gaaacaguaa uggaauuuca acaaaaaaac      660

aacagacuac uagaaauaac ccgagaguuc ucaguuaaug caggaguaac aacaccaguc      720

ucaacauaca ugcucacaaa cucagaacuc cuaucacuaa uaaaugacau gccaauaaca      780

aacgaccaaa aaaaacucau gucuaacaac guccaaauag uaagacaaca auccuacagc      840

auaaugugua uaauaaaaga agaaguuuua gcauacgucg uacaacuacc cuuauauggc      900

guaauagaua caccaugcug gaaacuccau accucaccuc uauguacaac aaauaccaaa      960

gaagguucua auauaugccu aacacgaacu gaccgaggau gguacuguga caacgcagga     1020

ucagucucuu ucuuuccaca agcagaaacc ugcaaaguau gcaguaaccg cguauuuugc     1080

gacacaauga acucccuaac cuuaccauca gaaguaaacu uauguaacgu agacauauuc     1140

aauccaaaau augacugcaa aauaaugaca ucaaaaacag acguaagcuc aucaguaaua     1200

acuucacuag gcgcaauugu aucaugcuau ggaaaaacca aauguaccgc auccaacaaa     1260

aauaaaggaa uaauaaaaac cuucucuaac ggaugcgacu acguaucaaa caaaggugua     1320

gauacaguuu cuguaggaaa cacacucuac uauguaaaua aacaagaagg aaaaucacua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccac uuguauuucc aucugaugaa     1440

uuugaugcaa gcauaucaca aguaaacgaa aaaauaaacc aaucucuagc cuuuauacga     1500

aaaagcgacg aauuacuaca uaacgucaac gcuggaaaau caacaacaaa cauaaugaua     1560

acaacaauaa uaauaguaau aauagucauc cuauuaucac uaaucgccgu aggacuacuc     1620

cuauacugca aagcuagaua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7283
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7283
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacuauccu cacagcaguc acuuucugcu ucgccucagg acaaaacaua      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca aaggcuaccu cucagcgcuc      240

cgcaccggcu gguacacauc cgucaucacc aucgaacuaa gcaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa aguuaaacuc aucaagcaag aacucgacaa auacaaaaac      360

gcagucacag aacuucaaau gcucaugugc uccacacccg ccacagguuc uggcucagca      420

aucgcaagcg gcgucgccgu augcaaaguc cuucaccucg aaggcgaagu caacaaaauc      480

aaauccgccc uccucuccac caauaaagcu gucgucucac ucuccaacgg cgucagcguc      540

cucacauuca aaguccucga ccucaaaaac uacauagaca agcaacuccu cccgauacuc      600

aacaaacaaa gcugcucuau cuccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaucgucucc ucgaaaucac ccgcgaguuc ucaguaaacg ccggggucac cacaccaguc      720

uccaccuaca ugcucaccaa cuccgaacuc cuuagccuca uaaacgacau gcccauaacc      780

aacgaccaaa agaaacucau gagcaacaac guacaaauag uccgacaaca auccuauucc      840

aucaugugua ucaucaaaga agaaguccuc gcauacguag uccaacuccc ccuauacggc      900

guaaucgaca ccccauguug gaaacuccac accucaccac ucuguaccac caacaccaaa      960

gaaggcucaa acaucugccu cacccgcaca gaccgcggcu gguacugcga caacgcgggc     1020

uccgucagcu ucuuucccca agcggaaacc ugcaaagucu gcagcaacag agucuucugc     1080

gacacuauga acucccucac ccuccccuca gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aaucaugacc agcaaaacug acgucuccuc guccgucauc     1200

accucacucg gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac auucagcaac ggcugcgacu acgucucgaa caaaggaguc     1320

gacaccguau cagugggcaa cacccuauac uacguaaaca agcaagaagg caaaucacuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucucuca agucaacgag aaaaucaacc aaucccuugc cuucauacgu     1500

aaaagcgacg aacuccuuca caacguaaac gccgggaaau ccaccacuaa cauaaugauc     1560

accaccauca ucaucguuau cauagucauc cuccucucuc ucauagcagu cggccuacuc     1620

cuguacugca aagcgcgcua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1680

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1740

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1860

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1920


<210>  7284
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7284
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7285
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7285
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7286
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7286
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7287
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7287
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacggug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7288
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7288
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7289
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7289
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7290
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7290
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccucaaagca      120

aacgcaauua caaccauacu aaccgcuguc accuuuuguu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacaugcucc gcaguaucua aaggauaccu cagcgcguua      240

agaacaggau gguacacauc gguaauaacc aucgaauuau ccaacauaaa agaaaauaaa      300

ugcaauggaa cagacgcaaa agucaaauua auuaaacaag aacuagacaa auauaaaaac      360

gcaguaaccg aauuacaaau gcuaaugugu ucaacaccag caacaggauc aggaucagcu      420

auagcuucag gaguugccgu augcaaagug cuacacuuag aaggagaagu gaauaaaaua      480

aaaucagcuc uauuaucaac gaacaaagcc guaguaucuc uaucaaaugg cguaucagua      540

cucacauuca aaguacucga ccuaaaaaac uauauagaua aacaacuauu acccauccua      600

aauaaacaaa gcugcucuau aucaaacauc gaaacaguaa uggaauuuca acaaaaaaac      660

aacagacuac uagaaauaac ccgagaguuc ucaguuaaug caggaguaac aacaccaguc      720

ucaacauaca ugcucacaaa cucagaacuc cuaucacuaa uaaaugacau gccaauaaca      780

aacgaccaaa aaaaacucau gucuaacaac guccaaauag uaagacaaca auccuacagc      840

auaaugugua uaauaaaaga agaaguuuua gcauacgucg uacaacuacc cuuauauggc      900

guaauagaua caccaugcug gaaacuccau accucaccuc uauguacaac aaauaccaaa      960

gaagguucua auauaugccu aacacgaacu gaccgaggau gguacuguga caacgcagga     1020

ucagucucuu ucuuuccaca agcagaaacc ugcaaaguau gcaguaaccg cguauuuugc     1080

gacacaauga acucccuaac cuuaccauca gaaguaaacu uauguaacgu agacauauuc     1140

aauccaaaau augacugcaa aauaaugaca ucaaaaacag acguaagcuc aucaguaaua     1200

acuucacuag gcgcaauugu aucaugcuau ggaaaaacca aauguaccgc auccaacaaa     1260

aauaaaggaa uaauaaaaac cuucucuaac ggaugcgacu acguaucaaa caaaggugua     1320

gauacaguuu cuguaggaaa cacacucuac uauguaaaua aacaagaagg aaaaucacua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccac uuguauuucc aucugaugaa     1440

uuugaugcaa gcauaucaca aguaaacgaa aaaauaaacc aaucucuagc cuuuauacga     1500

aaaagcgacg aauuacuaca uaacgucaac gcuggaaaau caacaacaaa cauaaugaua     1560

acaacaauaa uaauaguaau aauagucauc cuauuaucac uaaucgccgu aggacuacuc     1620

cuauacugca aagcuagaua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7291
<211>  1916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7291
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacuauccu cacagcaguc acuuucugcu ucgccucagg acaaaacaua      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca aaggcuaccu cucagcgcuc      240

cgcaccggcu gguacacauc cgucaucacc aucgaacuaa gcaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa aguuaaacuc aucaagcaag aacucgacaa auacaaaaac      360

gcagucacag aacuucaaau gcucaugugc uccacacccg ccacagguuc uggcucagca      420

aucgcaagcg gcgucgccgu augcaaaguc cuucaccucg aaggcgaagu caacaaaauc      480

aaauccgccc uccucuccac caauaaagcu gucgucucac ucuccaacgg cgucagcguc      540

cucacauuca aaguccucga ccucaaaaac uacauagaca agcaacuccu cccgauacuc      600

aacaaacaaa gcugcucuau cuccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaucgucucc ucgaaaucac ccgcgaguuc ucaguaaacg ccggggucac cacaccaguc      720

uccaccuaca ugcucaccaa cuccgaacuc cuuagccuca uaaacgacau gcccauaacc      780

aacgaccaaa agaaacucau gagcaacaac guacaaauag uccgacaaca auccuauucc      840

aucaugugua ucaucaaaga agaaguccuc gcauacguag uccaacuccc ccuauacggc      900

guaaucgaca ccccauguug gaaacuccac accucaccac ucuguaccac caacaccaaa      960

gaaggcucaa acaucugccu cacccgcaca gaccgcggcu gguacugcga caacgcgggc     1020

uccgucagcu ucuuucccca agcggaaacc ugcaaagucu gcagcaacag agucuucugc     1080

gacacuauga acucccucac ccuccccuca gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aaucaugacc agcaaaacug acgucuccuc guccgucauc     1200

accucacucg gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac auucagcaac ggcugcgacu acgucucgaa caaaggaguc     1320

gacaccguau cagugggcaa cacccuauac uacguaaaca agcaagaagg caaaucacuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucucuca agucaacgag aaaaucaacc aaucccuugc cuucauacgu     1500

aaaagcgacg aacuccuuca caacguaaac gccgggaaau ccaccacuaa cauaaugauc     1560

accaccauca ucaucguuau cauagucauc cuccucucuc ucauagcagu cggccuacuc     1620

cuguacugca aagcgcgcua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1680

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1740

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1860

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1916


<210>  7292
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7292
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7293
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7293
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7294
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7294
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7295
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7295
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7296
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7296
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7297
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7297
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7298
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7298
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccucaa agcaaacgca      120

auuacaacca uacuaaccgc ugucaccuuu uguuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacaug cuccgcagua ucuaaaggau accucagcgc guuaagaaca      240

ggaugguaca caucgguaau aaccaucgaa uuauccaaca uaaaagaaaa uaaaugcaau      300

ggaacagacg caaaagucaa auuaauuaaa caagaacuag acaaauauaa aaacgcagua      360

accgaauuac aaaugcuaau guguucaaca ccagcaacag gaucaggauc agcuauagcu      420

ucaggaguug ccguaugcaa agugcuacac uuagaaggag aagugaauaa aauaaaauca      480

gcucuauuau caacgaacaa agccguagua ucucuaucaa auggcguauc aguacucaca      540

uucaaaguac ucgaccuaaa aaacuauaua gauaaacaac uauuacccau ccuaaauaaa      600

caaagcugcu cuauaucaaa caucgaaaca guaauggaau uucaacaaaa aaacaacaga      660

cuacuagaaa uaacccgaga guucucaguu aaugcaggag uaacaacacc agucucaaca      720

uacaugcuca caaacucaga acuccuauca cuaauaaaug acaugccaau aacaaacgac      780

caaaaaaaac ucaugucuaa caacguccaa auaguaagac aacaauccua cagcauaaug      840

uguauaauaa aagaagaagu uuuagcauac gucguacaac uacccuuaua uggcguaaua      900

gauacaccau gcuggaaacu ccauaccuca ccucuaugua caacaaauac caaagaaggu      960

ucuaauauau gccuaacacg aacugaccga ggaugguacu gugacaacgc aggaucaguc     1020

ucuuucuuuc cacaagcaga aaccugcaaa guaugcagua accgcguauu uugcgacaca     1080

augaacuccc uaaccuuacc aucagaagua aacuuaugua acguagacau auucaaucca     1140

aaauaugacu gcaaaauaau gacaucaaaa acagacguaa gcucaucagu aauaacuuca     1200

cuaggcgcaa uuguaucaug cuauggaaaa accaaaugua ccgcauccaa caaaaauaaa     1260

ggaauaauaa aaaccuucuc uaacggaugc gacuacguau caaacaaagg uguagauaca     1320

guuucuguag gaaacacacu cuacuaugua aauaaacaag aaggaaaauc acuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccacuuguau uuccaucuga ugaauuugau     1440

gcaagcauau cacaaguaaa cgaaaaaaua aaccaaucuc uagccuuuau acgaaaaagc     1500

gacgaauuac uacauaacgu caacgcugga aaaucaacaa caaacauaau gauaacaaca     1560

auaauaauag uaauaauagu cauccuauua ucacuaaucg ccguaggacu acuccuauac     1620

ugcaaagcua gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7299
<211>  1834
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7299
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacua uccucacagc agucacuuuc ugcuucgccu caggacaaaa cauaaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaaaggcu accucucagc gcuccgcacc      240

ggcugguaca cauccgucau caccaucgaa cuaagcaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaaguuaa acucaucaag caagaacucg acaaauacaa aaacgcaguc      360

acagaacuuc aaaugcucau gugcuccaca cccgccacag guucuggcuc agcaaucgca      420

agcggcgucg ccguaugcaa aguccuucac cucgaaggcg aagucaacaa aaucaaaucc      480

gcccuccucu ccaccaauaa agcugucguc ucacucucca acggcgucag cguccucaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaagcaac uccucccgau acucaacaaa      600

caaagcugcu cuaucuccaa caucgaaacc gucauggagu uccaacagaa aaacaaucgu      660

cuccucgaaa ucacccgcga guucucagua aacgccgggg ucaccacacc agucuccacc      720

uacaugcuca ccaacuccga acuccuuagc cucauaaacg acaugcccau aaccaacgac      780

caaaagaaac ucaugagcaa caacguacaa auaguccgac aacaauccua uuccaucaug      840

uguaucauca aagaagaagu ccucgcauac guaguccaac ucccccuaua cggcguaauc      900

gacaccccau guuggaaacu ccacaccuca ccacucugua ccaccaacac caaagaaggc      960

ucaaacaucu gccucacccg cacagaccgc ggcugguacu gcgacaacgc gggcuccguc     1020

agcuucuuuc cccaagcgga aaccugcaaa gucugcagca acagagucuu cugcgacacu     1080

augaacuccc ucacccuccc cucagaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaaucau gaccagcaaa acugacgucu ccucguccgu caucaccuca     1200

cucggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaacauucag caacggcugc gacuacgucu cgaacaaagg agucgacacc     1320

guaucagugg gcaacacccu auacuacgua aacaagcaag aaggcaaauc acucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cucaagucaa cgagaaaauc aaccaauccc uugccuucau acguaaaagc     1500

gacgaacucc uucacaacgu aaacgccggg aaauccacca cuaacauaau gaucaccacc     1560

aucaucaucg uuaucauagu cauccuccuc ucucucauag cagucggccu acuccuguac     1620

ugcaaagcgc gcuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1680

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1800

ccccccaaag gcucuuuuca gagccaccag aauu                                 1834


<210>  7300
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7300
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7301
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7301
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7302
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7302
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7303
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7303
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7304
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7304
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7305
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7305
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7306
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7306
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccucaaa      120

gcaaacgcaa uuacaaccau acuaaccgcu gucaccuuuu guuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacaugc uccgcaguau cuaaaggaua ccucagcgcg      240

uuaagaacag gaugguacac aucgguaaua accaucgaau uauccaacau aaaagaaaau      300

aaaugcaaug gaacagacgc aaaagucaaa uuaauuaaac aagaacuaga caaauauaaa      360

aacgcaguaa ccgaauuaca aaugcuaaug uguucaacac cagcaacagg aucaggauca      420

gcuauagcuu caggaguugc cguaugcaaa gugcuacacu uagaaggaga agugaauaaa      480

auaaaaucag cucuauuauc aacgaacaaa gccguaguau cucuaucaaa uggcguauca      540

guacucacau ucaaaguacu cgaccuaaaa aacuauauag auaaacaacu auuacccauc      600

cuaaauaaac aaagcugcuc uauaucaaac aucgaaacag uaauggaauu ucaacaaaaa      660

aacaacagac uacuagaaau aacccgagag uucucaguua augcaggagu aacaacacca      720

gucucaacau acaugcucac aaacucagaa cuccuaucac uaauaaauga caugccaaua      780

acaaacgacc aaaaaaaacu caugucuaac aacguccaaa uaguaagaca acaauccuac      840

agcauaaugu guauaauaaa agaagaaguu uuagcauacg ucguacaacu acccuuauau      900

ggcguaauag auacaccaug cuggaaacuc cauaccucac cucuauguac aacaaauacc      960

aaagaagguu cuaauauaug ccuaacacga acugaccgag gaugguacug ugacaacgca     1020

ggaucagucu cuuucuuucc acaagcagaa accugcaaag uaugcaguaa ccgcguauuu     1080

ugcgacacaa ugaacucccu aaccuuacca ucagaaguaa acuuauguaa cguagacaua     1140

uucaauccaa aauaugacug caaaauaaug acaucaaaaa cagacguaag cucaucagua     1200

auaacuucac uaggcgcaau uguaucaugc uauggaaaaa ccaaauguac cgcauccaac     1260

aaaaauaaag gaauaauaaa aaccuucucu aacggaugcg acuacguauc aaacaaaggu     1320

guagauacag uuucuguagg aaacacacuc uacuauguaa auaaacaaga aggaaaauca     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cacuuguauu uccaucugau     1440

gaauuugaug caagcauauc acaaguaaac gaaaaaauaa accaaucucu agccuuuaua     1500

cgaaaaagcg acgaauuacu acauaacguc aacgcuggaa aaucaacaac aaacauaaug     1560

auaacaacaa uaauaauagu aauaauaguc auccuauuau cacuaaucgc cguaggacua     1620

cuccuauacu gcaaagcuag auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7307
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7307
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacuau ccucacagca gucacuuucu gcuucgccuc aggacaaaac      180

auaaccgaag aguucuacca auccacaugc uccgccgucu ccaaaggcua ccucucagcg      240

cuccgcaccg gcugguacac auccgucauc accaucgaac uaagcaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaaguuaaa cucaucaagc aagaacucga caaauacaaa      360

aacgcaguca cagaacuuca aaugcucaug ugcuccacac ccgccacagg uucuggcuca      420

gcaaucgcaa gcggcgucgc cguaugcaaa guccuucacc ucgaaggcga agucaacaaa      480

aucaaauccg cccuccucuc caccaauaaa gcugucgucu cacucuccaa cggcgucagc      540

guccucacau ucaaaguccu cgaccucaaa aacuacauag acaagcaacu ccucccgaua      600

cucaacaaac aaagcugcuc uaucuccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaucguc uccucgaaau cacccgcgag uucucaguaa acgccggggu caccacacca      720

gucuccaccu acaugcucac caacuccgaa cuccuuagcc ucauaaacga caugcccaua      780

accaacgacc aaaagaaacu caugagcaac aacguacaaa uaguccgaca acaauccuau      840

uccaucaugu guaucaucaa agaagaaguc cucgcauacg uaguccaacu cccccuauac      900

ggcguaaucg acaccccaug uuggaaacuc cacaccucac cacucuguac caccaacacc      960

aaagaaggcu caaacaucug ccucacccgc acagaccgcg gcugguacug cgacaacgcg     1020

ggcuccguca gcuucuuucc ccaagcggaa accugcaaag ucugcagcaa cagagucuuc     1080

ugcgacacua ugaacucccu cacccucccc ucagaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaaucaug accagcaaaa cugacgucuc cucguccguc     1200

aucaccucac ucggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aacauucagc aacggcugcg acuacgucuc gaacaaagga     1320

gucgacaccg uaucaguggg caacacccua uacuacguaa acaagcaaga aggcaaauca     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ucaagucaac gagaaaauca accaaucccu ugccuucaua     1500

cguaaaagcg acgaacuccu ucacaacgua aacgccggga aauccaccac uaacauaaug     1560

aucaccacca ucaucaucgu uaucauaguc auccuccucu cucucauagc agucggccua     1620

cuccuguacu gcaaagcgcg cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7308
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7308
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7309
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7309
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7310
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7310
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7311
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7311
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7312
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7312
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7313
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7313
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7314
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7314
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccucaa agcaaacgca      120

auuacaacca uacuaaccgc ugucaccuuu uguuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacaug cuccgcagua ucuaaaggau accucagcgc guuaagaaca      240

ggaugguaca caucgguaau aaccaucgaa uuauccaaca uaaaagaaaa uaaaugcaau      300

ggaacagacg caaaagucaa auuaauuaaa caagaacuag acaaauauaa aaacgcagua      360

accgaauuac aaaugcuaau guguucaaca ccagcaacag gaucaggauc agcuauagcu      420

ucaggaguug ccguaugcaa agugcuacac uuagaaggag aagugaauaa aauaaaauca      480

gcucuauuau caacgaacaa agccguagua ucucuaucaa auggcguauc aguacucaca      540

uucaaaguac ucgaccuaaa aaacuauaua gauaaacaac uauuacccau ccuaaauaaa      600

caaagcugcu cuauaucaaa caucgaaaca guaauggaau uucaacaaaa aaacaacaga      660

cuacuagaaa uaacccgaga guucucaguu aaugcaggag uaacaacacc agucucaaca      720

uacaugcuca caaacucaga acuccuauca cuaauaaaug acaugccaau aacaaacgac      780

caaaaaaaac ucaugucuaa caacguccaa auaguaagac aacaauccua cagcauaaug      840

uguauaauaa aagaagaagu uuuagcauac gucguacaac uacccuuaua uggcguaaua      900

gauacaccau gcuggaaacu ccauaccuca ccucuaugua caacaaauac caaagaaggu      960

ucuaauauau gccuaacacg aacugaccga ggaugguacu gugacaacgc aggaucaguc     1020

ucuuucuuuc cacaagcaga aaccugcaaa guaugcagua accgcguauu uugcgacaca     1080

augaacuccc uaaccuuacc aucagaagua aacuuaugua acguagacau auucaaucca     1140

aaauaugacu gcaaaauaau gacaucaaaa acagacguaa gcucaucagu aauaacuuca     1200

cuaggcgcaa uuguaucaug cuauggaaaa accaaaugua ccgcauccaa caaaaauaaa     1260

ggaauaauaa aaaccuucuc uaacggaugc gacuacguau caaacaaagg uguagauaca     1320

guuucuguag gaaacacacu cuacuaugua aauaaacaag aaggaaaauc acuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccacuuguau uuccaucuga ugaauuugau     1440

gcaagcauau cacaaguaaa cgaaaaaaua aaccaaucuc uagccuuuau acgaaaaagc     1500

gacgaauuac uacauaacgu caacgcugga aaaucaacaa caaacauaau gauaacaaca     1560

auaauaauag uaauaauagu cauccuauua ucacuaaucg ccguaggacu acuccuauac     1620

ugcaaagcua gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7315
<211>  1898
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7315
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacua uccucacagc agucacuuuc ugcuucgccu caggacaaaa cauaaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaaaggcu accucucagc gcuccgcacc      240

ggcugguaca cauccgucau caccaucgaa cuaagcaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaaguuaa acucaucaag caagaacucg acaaauacaa aaacgcaguc      360

acagaacuuc aaaugcucau gugcuccaca cccgccacag guucuggcuc agcaaucgca      420

agcggcgucg ccguaugcaa aguccuucac cucgaaggcg aagucaacaa aaucaaaucc      480

gcccuccucu ccaccaauaa agcugucguc ucacucucca acggcgucag cguccucaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaagcaac uccucccgau acucaacaaa      600

caaagcugcu cuaucuccaa caucgaaacc gucauggagu uccaacagaa aaacaaucgu      660

cuccucgaaa ucacccgcga guucucagua aacgccgggg ucaccacacc agucuccacc      720

uacaugcuca ccaacuccga acuccuuagc cucauaaacg acaugcccau aaccaacgac      780

caaaagaaac ucaugagcaa caacguacaa auaguccgac aacaauccua uuccaucaug      840

uguaucauca aagaagaagu ccucgcauac guaguccaac ucccccuaua cggcguaauc      900

gacaccccau guuggaaacu ccacaccuca ccacucugua ccaccaacac caaagaaggc      960

ucaaacaucu gccucacccg cacagaccgc ggcugguacu gcgacaacgc gggcuccguc     1020

agcuucuuuc cccaagcgga aaccugcaaa gucugcagca acagagucuu cugcgacacu     1080

augaacuccc ucacccuccc cucagaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaaucau gaccagcaaa acugacgucu ccucguccgu caucaccuca     1200

cucggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaacauucag caacggcugc gacuacgucu cgaacaaagg agucgacacc     1320

guaucagugg gcaacacccu auacuacgua aacaagcaag aaggcaaauc acucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cucaagucaa cgagaaaauc aaccaauccc uugccuucau acguaaaagc     1500

gacgaacucc uucacaacgu aaacgccggg aaauccacca cuaacauaau gaucaccacc     1560

aucaucaucg uuaucauagu cauccuccuc ucucucauag cagucggccu acuccuguac     1620

ugcaaagcgc gcuaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1680

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1740

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1860

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1898


<210>  7316
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7316
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7317
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7317
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7318
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7318
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7319
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7319
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7320
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7320
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7321
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7321
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcugag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7322
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7322
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ucaaagcaaa cgcaauuaca accauacuaa ccgcugucac cuuuuguuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa caugcuccgc aguaucuaaa      300

ggauaccuca gcgcguuaag aacaggaugg uacacaucgg uaauaaccau cgaauuaucc      360

aacauaaaag aaaauaaaug caauggaaca gacgcaaaag ucaaauuaau uaaacaagaa      420

cuagacaaau auaaaaacgc aguaaccgaa uuacaaaugc uaauguguuc aacaccagca      480

acaggaucag gaucagcuau agcuucagga guugccguau gcaaagugcu acacuuagaa      540

ggagaaguga auaaaauaaa aucagcucua uuaucaacga acaaagccgu aguaucucua      600

ucaaauggcg uaucaguacu cacauucaaa guacucgacc uaaaaaacua uauagauaaa      660

caacuauuac ccauccuaaa uaaacaaagc ugcucuauau caaacaucga aacaguaaug      720

gaauuucaac aaaaaaacaa cagacuacua gaaauaaccc gagaguucuc aguuaaugca      780

ggaguaacaa caccagucuc aacauacaug cucacaaacu cagaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacucaugu cuaacaacgu ccaaauagua      900

agacaacaau ccuacagcau aauguguaua auaaaagaag aaguuuuagc auacgucgua      960

caacuacccu uauauggcgu aauagauaca ccaugcugga aacuccauac cucaccucua     1020

uguacaacaa auaccaaaga agguucuaau auaugccuaa cacgaacuga ccgaggaugg     1080

uacugugaca acgcaggauc agucucuuuc uuuccacaag cagaaaccug caaaguaugc     1140

aguaaccgcg uauuuugcga cacaaugaac ucccuaaccu uaccaucaga aguaaacuua     1200

uguaacguag acauauucaa uccaaaauau gacugcaaaa uaaugacauc aaaaacagac     1260

guaagcucau caguaauaac uucacuaggc gcaauuguau caugcuaugg aaaaaccaaa     1320

uguaccgcau ccaacaaaaa uaaaggaaua auaaaaaccu ucucuaacgg augcgacuac     1380

guaucaaaca aagguguaga uacaguuucu guaggaaaca cacucuacua uguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaagga gaaccaauaa uaaacuucua ugacccacuu     1500

guauuuccau cugaugaauu ugaugcaagc auaucacaag uaaacgaaaa aauaaaccaa     1560

ucucuagccu uuauacgaaa aagcgacgaa uuacuacaua acgucaacgc uggaaaauca     1620

acaacaaaca uaaugauaac aacaauaaua auaguaauaa uagucauccu auuaucacua     1680

aucgccguag gacuacuccu auacugcaaa gcuagauaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7323
<211>  2214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7323
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acuauccuca cagcagucac uuucugcuuc      240

gccucaggac aaaacauaac cgaagaguuc uaccaaucca caugcuccgc cgucuccaaa      300

ggcuaccucu cagcgcuccg caccggcugg uacacauccg ucaucaccau cgaacuaagc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaaag uuaaacucau caagcaagaa      420

cucgacaaau acaaaaacgc agucacagaa cuucaaaugc ucaugugcuc cacacccgcc      480

acagguucug gcucagcaau cgcaagcggc gucgccguau gcaaaguccu ucaccucgaa      540

ggcgaaguca acaaaaucaa auccgcccuc cucuccacca auaaagcugu cgucucacuc      600

uccaacggcg ucagcguccu cacauucaaa guccucgacc ucaaaaacua cauagacaag      660

caacuccucc cgauacucaa caaacaaagc ugcucuaucu ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ucgucuccuc gaaaucaccc gcgaguucuc aguaaacgcc      780

ggggucacca caccagucuc caccuacaug cucaccaacu ccgaacuccu uagccucaua      840

aacgacaugc ccauaaccaa cgaccaaaag aaacucauga gcaacaacgu acaaauaguc      900

cgacaacaau ccuauuccau cauguguauc aucaaagaag aaguccucgc auacguaguc      960

caacuccccc uauacggcgu aaucgacacc ccauguugga aacuccacac cucaccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuca cccgcacaga ccgcggcugg     1080

uacugcgaca acgcgggcuc cgucagcuuc uuuccccaag cggaaaccug caaagucugc     1140

agcaacagag ucuucugcga cacuaugaac ucccucaccc uccccucaga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa ucaugaccag caaaacugac     1260

gucuccucgu ccgucaucac cucacucggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaacau ucagcaacgg cugcgacuac     1380

gucucgaaca aaggagucga caccguauca gugggcaaca cccuauacua cguaaacaag     1440

caagaaggca aaucacucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucucaag ucaacgagaa aaucaaccaa     1560

ucccuugccu ucauacguaa aagcgacgaa cuccuucaca acguaaacgc cgggaaaucc     1620

accacuaaca uaaugaucac caccaucauc aucguuauca uagucauccu ccucucucuc     1680

auagcagucg gccuacuccu guacugcaaa gcgcgcuaag gacuagugaa gggaacaccc     1740

aaauuuaauu cagccuuaag cacaauuaau uaagagugaa acguaauugu acaagcaguu     1800

ggucacccac cauagggcau gaucaacacc gcaaccuuuc cuuuuucccc cagugauucu     1860

gaaaaacccc ucuucccuuc agcuugcuua gauguuccaa auuuaguaag cuuaaggcgg     1920

ccuacagaag aaaaagaaaa aaaaggccac aaaaguuccc ucucacuuuc aguaaauaaa     1980

auaaaagcag caacagaaau aaagaaauaa augaaauuca aaaugaaaua aauauugugu     2040

ugugcagcau uaaaaaauca auaaaaauua aaaaugagca agaucuaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     2160

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           2214


<210>  7324
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7324
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7325
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7325
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7326
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7326
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7327
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7327
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7328
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7328
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7329
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7329
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7330
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7330
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccucaaagc aaacgcaauu acaaccauac      120

uaaccgcugu caccuuuugu uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacaugcuc cgcaguaucu aaaggauacc ucagcgcguu aagaacagga ugguacacau      240

cgguaauaac caucgaauua uccaacauaa aagaaaauaa augcaaugga acagacgcaa      300

aagucaaauu aauuaaacaa gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa      360

ugcuaaugug uucaacacca gcaacaggau caggaucagc uauagcuuca ggaguugccg      420

uaugcaaagu gcuacacuua gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa      480

cgaacaaagc cguaguaucu cuaucaaaug gcguaucagu acucacauuc aaaguacucg      540

accuaaaaaa cuauauagau aaacaacuau uacccauccu aaauaaacaa agcugcucua      600

uaucaaacau cgaaacagua auggaauuuc aacaaaaaaa caacagacua cuagaaauaa      660

cccgagaguu cucaguuaau gcaggaguaa caacaccagu cucaacauac augcucacaa      720

acucagaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa cguccaaaua guaagacaac aauccuacag cauaaugugu auaauaaaag      840

aagaaguuuu agcauacguc guacaacuac ccuuauaugg cguaauagau acaccaugcu      900

ggaaacucca uaccucaccu cuauguacaa caaauaccaa agaagguucu aauauaugcc      960

uaacacgaac ugaccgagga ugguacugug acaacgcagg aucagucucu uucuuuccac     1020

aagcagaaac cugcaaagua ugcaguaacc gcguauuuug cgacacaaug aacucccuaa     1080

ccuuaccauc agaaguaaac uuauguaacg uagacauauu caauccaaaa uaugacugca     1140

aaauaaugac aucaaaaaca gacguaagcu caucaguaau aacuucacua ggcgcaauug     1200

uaucaugcua uggaaaaacc aaauguaccg cauccaacaa aaauaaagga auaauaaaaa     1260

ccuucucuaa cggaugcgac uacguaucaa acaaaggugu agauacaguu ucuguaggaa     1320

acacacucua cuauguaaau aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca cuuguauuuc caucugauga auuugaugca agcauaucac     1440

aaguaaacga aaaaauaaac caaucucuag ccuuuauacg aaaaagcgac gaauuacuac     1500

auaacgucaa cgcuggaaaa ucaacaacaa acauaaugau aacaacaaua auaauaguaa     1560

uaauagucau ccuauuauca cuaaucgccg uaggacuacu ccuauacugc aaagcuagau     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7331
<211>  1897
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7331
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacuaucc      120

ucacagcagu cacuuucugc uucgccucag gacaaaacau aaccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau      240

ccgucaucac caucgaacua agcaacauaa aagaaaacaa augcaacggc accgacgcca      300

aaguuaaacu caucaagcaa gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa      360

ugcucaugug cuccacaccc gccacagguu cuggcucagc aaucgcaagc ggcgucgccg      420

uaugcaaagu ccuucaccuc gaaggcgaag ucaacaaaau caaauccgcc cuccucucca      480

ccaauaaagc ugucgucuca cucuccaacg gcgucagcgu ccucacauuc aaaguccucg      540

accucaaaaa cuacauagac aagcaacucc ucccgauacu caacaaacaa agcugcucua      600

ucuccaacau cgaaaccguc auggaguucc aacagaaaaa caaucgucuc cucgaaauca      660

cccgcgaguu cucaguaaac gccgggguca ccacaccagu cuccaccuac augcucacca      720

acuccgaacu ccuuagccuc auaaacgaca ugcccauaac caacgaccaa aagaaacuca      780

ugagcaacaa cguacaaaua guccgacaac aauccuauuc caucaugugu aucaucaaag      840

aagaaguccu cgcauacgua guccaacucc cccuauacgg cguaaucgac accccauguu      900

ggaaacucca caccucacca cucuguacca ccaacaccaa agaaggcuca aacaucugcc      960

ucacccgcac agaccgcggc ugguacugcg acaacgcggg cuccgucagc uucuuucccc     1020

aagcggaaac cugcaaaguc ugcagcaaca gagucuucug cgacacuaug aacucccuca     1080

cccuccccuc agaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaaucaugac cagcaaaacu gacgucuccu cguccgucau caccucacuc ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

cauucagcaa cggcugcgac uacgucucga acaaaggagu cgacaccgua ucagugggca     1320

acacccuaua cuacguaaac aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucucuc     1440

aagucaacga gaaaaucaac caaucccuug ccuucauacg uaaaagcgac gaacuccuuc     1500

acaacguaaa cgccgggaaa uccaccacua acauaaugau caccaccauc aucaucguua     1560

ucauagucau ccuccucucu cucauagcag ucggccuacu ccuguacugc aaagcgcgcu     1620

aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu     1680

guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa     1740

uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1860

ccccccccca aaggcucuuu ucagagccac cagaauu                              1897


<210>  7332
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7332
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7333
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7333
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7334
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7334
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7335
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7335
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7336
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7336
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7337
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7337
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcugag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7338
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7338
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ucaaagcaaa cgcaauuaca accauacuaa ccgcugucac cuuuuguuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa caugcuccgc aguaucuaaa      300

ggauaccuca gcgcguuaag aacaggaugg uacacaucgg uaauaaccau cgaauuaucc      360

aacauaaaag aaaauaaaug caauggaaca gacgcaaaag ucaaauuaau uaaacaagaa      420

cuagacaaau auaaaaacgc aguaaccgaa uuacaaaugc uaauguguuc aacaccagca      480

acaggaucag gaucagcuau agcuucagga guugccguau gcaaagugcu acacuuagaa      540

ggagaaguga auaaaauaaa aucagcucua uuaucaacga acaaagccgu aguaucucua      600

ucaaauggcg uaucaguacu cacauucaaa guacucgacc uaaaaaacua uauagauaaa      660

caacuauuac ccauccuaaa uaaacaaagc ugcucuauau caaacaucga aacaguaaug      720

gaauuucaac aaaaaaacaa cagacuacua gaaauaaccc gagaguucuc aguuaaugca      780

ggaguaacaa caccagucuc aacauacaug cucacaaacu cagaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacucaugu cuaacaacgu ccaaauagua      900

agacaacaau ccuacagcau aauguguaua auaaaagaag aaguuuuagc auacgucgua      960

caacuacccu uauauggcgu aauagauaca ccaugcugga aacuccauac cucaccucua     1020

uguacaacaa auaccaaaga agguucuaau auaugccuaa cacgaacuga ccgaggaugg     1080

uacugugaca acgcaggauc agucucuuuc uuuccacaag cagaaaccug caaaguaugc     1140

aguaaccgcg uauuuugcga cacaaugaac ucccuaaccu uaccaucaga aguaaacuua     1200

uguaacguag acauauucaa uccaaaauau gacugcaaaa uaaugacauc aaaaacagac     1260

guaagcucau caguaauaac uucacuaggc gcaauuguau caugcuaugg aaaaaccaaa     1320

uguaccgcau ccaacaaaaa uaaaggaaua auaaaaaccu ucucuaacgg augcgacuac     1380

guaucaaaca aagguguaga uacaguuucu guaggaaaca cacucuacua uguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaagga gaaccaauaa uaaacuucua ugacccacuu     1500

guauuuccau cugaugaauu ugaugcaagc auaucacaag uaaacgaaaa aauaaaccaa     1560

ucucuagccu uuauacgaaa aagcgacgaa uuacuacaua acgucaacgc uggaaaauca     1620

acaacaaaca uaaugauaac aacaauaaua auaguaauaa uagucauccu auuaucacua     1680

aucgccguag gacuacuccu auacugcaaa gcuagauaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7339
<211>  1994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7339
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acuauccuca cagcagucac uuucugcuuc      240

gccucaggac aaaacauaac cgaagaguuc uaccaaucca caugcuccgc cgucuccaaa      300

ggcuaccucu cagcgcuccg caccggcugg uacacauccg ucaucaccau cgaacuaagc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaaag uuaaacucau caagcaagaa      420

cucgacaaau acaaaaacgc agucacagaa cuucaaaugc ucaugugcuc cacacccgcc      480

acagguucug gcucagcaau cgcaagcggc gucgccguau gcaaaguccu ucaccucgaa      540

ggcgaaguca acaaaaucaa auccgcccuc cucuccacca auaaagcugu cgucucacuc      600

uccaacggcg ucagcguccu cacauucaaa guccucgacc ucaaaaacua cauagacaag      660

caacuccucc cgauacucaa caaacaaagc ugcucuaucu ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ucgucuccuc gaaaucaccc gcgaguucuc aguaaacgcc      780

ggggucacca caccagucuc caccuacaug cucaccaacu ccgaacuccu uagccucaua      840

aacgacaugc ccauaaccaa cgaccaaaag aaacucauga gcaacaacgu acaaauaguc      900

cgacaacaau ccuauuccau cauguguauc aucaaagaag aaguccucgc auacguaguc      960

caacuccccc uauacggcgu aaucgacacc ccauguugga aacuccacac cucaccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuca cccgcacaga ccgcggcugg     1080

uacugcgaca acgcgggcuc cgucagcuuc uuuccccaag cggaaaccug caaagucugc     1140

agcaacagag ucuucugcga cacuaugaac ucccucaccc uccccucaga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa ucaugaccag caaaacugac     1260

gucuccucgu ccgucaucac cucacucggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaacau ucagcaacgg cugcgacuac     1380

gucucgaaca aaggagucga caccguauca gugggcaaca cccuauacua cguaaacaag     1440

caagaaggca aaucacucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucucaag ucaacgagaa aaucaaccaa     1560

ucccuugccu ucauacguaa aagcgacgaa cuccuucaca acguaaacgc cgggaaaucc     1620

accacuaaca uaaugaucac caccaucauc aucguuauca uagucauccu ccucucucuc     1680

auagcagucg gccuacuccu guacugcaaa gcgcgcuaag gacuagugga agcauuuucc     1740

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1800

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1860

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1980

gagccaccag aauu                                                       1994


<210>  7340
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7340
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      720

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      900

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      960

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1020

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1080

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1260

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1440

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1500

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1560

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1620

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7341
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7341
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      420

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      480

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      540

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      600

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      660

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      720

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      840

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      960

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg     1020

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1080

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1140

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1200

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1260

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1320

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1380

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1500

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1560

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1620

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7342
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7342
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      600

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      660

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      720

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      780

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      840

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      900

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      960

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1020

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1080

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1140

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1200

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1260

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1320

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1380

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1500

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1560

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1620

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7343
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7343
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      300

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      360

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      420

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      480

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      540

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      600

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      660

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      720

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      780

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      840

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua      900

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca      960

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc     1020

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1080

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1140

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1200

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1260

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1320

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1380

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1440

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1500

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1560

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1620

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7344
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7344
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      600

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      660

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      720

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      780

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      840

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      900

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      960

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1020

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1080

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1140

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1200

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1260

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1320

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1380

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1440

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1500

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1560

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1620

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7345
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7345
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      300

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      360

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      420

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      480

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      540

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      600

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      660

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      720

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      780

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      840

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug      900

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu      960

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga     1020

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1080

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1140

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1200

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1260

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1320

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1380

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1440

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1500

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1560

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1620

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu gaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7346
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7346
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaauuacuaa uccucaaagc aaacgcaauu acaaccauac uaaccgcugu caccuuuugu      180

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacaugcuc cgcaguaucu      240

aaaggauacc ucagcgcguu aagaacagga ugguacacau cgguaauaac caucgaauua      300

uccaacauaa aagaaaauaa augcaaugga acagacgcaa aagucaaauu aauuaaacaa      360

gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa ugcuaaugug uucaacacca      420

gcaacaggau caggaucagc uauagcuuca ggaguugccg uaugcaaagu gcuacacuua      480

gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa cgaacaaagc cguaguaucu      540

cuaucaaaug gcguaucagu acucacauuc aaaguacucg accuaaaaaa cuauauagau      600

aaacaacuau uacccauccu aaauaaacaa agcugcucua uaucaaacau cgaaacagua      660

auggaauuuc aacaaaaaaa caacagacua cuagaaauaa cccgagaguu cucaguuaau      720

gcaggaguaa caacaccagu cucaacauac augcucacaa acucagaacu ccuaucacua      780

auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca ugucuaacaa cguccaaaua      840

guaagacaac aauccuacag cauaaugugu auaauaaaag aagaaguuuu agcauacguc      900

guacaacuac ccuuauaugg cguaauagau acaccaugcu ggaaacucca uaccucaccu      960

cuauguacaa caaauaccaa agaagguucu aauauaugcc uaacacgaac ugaccgagga     1020

ugguacugug acaacgcagg aucagucucu uucuuuccac aagcagaaac cugcaaagua     1080

ugcaguaacc gcguauuuug cgacacaaug aacucccuaa ccuuaccauc agaaguaaac     1140

uuauguaacg uagacauauu caauccaaaa uaugacugca aaauaaugac aucaaaaaca     1200

gacguaagcu caucaguaau aacuucacua ggcgcaauug uaucaugcua uggaaaaacc     1260

aaauguaccg cauccaacaa aaauaaagga auaauaaaaa ccuucucuaa cggaugcgac     1320

uacguaucaa acaaaggugu agauacaguu ucuguaggaa acacacucua cuauguaaau     1380

aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1440

cuuguauuuc caucugauga auuugaugca agcauaucac aaguaaacga aaaaauaaac     1500

caaucucuag ccuuuauacg aaaaagcgac gaauuacuac auaacgucaa cgcuggaaaa     1560

ucaacaacaa acauaaugau aacaacaaua auaauaguaa uaauagucau ccuauuauca     1620

cuaaucgccg uaggacuacu ccuauacugc aaagcuagau aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7347
<211>  1874
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7347
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccucaaagc caacgccaua accacuaucc ucacagcagu cacuuucugc      180

uucgccucag gacaaaacau aaccgaagag uucuaccaau ccacaugcuc cgccgucucc      240

aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau ccgucaucac caucgaacua      300

agcaacauaa aagaaaacaa augcaacggc accgacgcca aaguuaaacu caucaagcaa      360

gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa ugcucaugug cuccacaccc      420

gccacagguu cuggcucagc aaucgcaagc ggcgucgccg uaugcaaagu ccuucaccuc      480

gaaggcgaag ucaacaaaau caaauccgcc cuccucucca ccaauaaagc ugucgucuca      540

cucuccaacg gcgucagcgu ccucacauuc aaaguccucg accucaaaaa cuacauagac      600

aagcaacucc ucccgauacu caacaaacaa agcugcucua ucuccaacau cgaaaccguc      660

auggaguucc aacagaaaaa caaucgucuc cucgaaauca cccgcgaguu cucaguaaac      720

gccgggguca ccacaccagu cuccaccuac augcucacca acuccgaacu ccuuagccuc      780

auaaacgaca ugcccauaac caacgaccaa aagaaacuca ugagcaacaa cguacaaaua      840

guccgacaac aauccuauuc caucaugugu aucaucaaag aagaaguccu cgcauacgua      900

guccaacucc cccuauacgg cguaaucgac accccauguu ggaaacucca caccucacca      960

cucuguacca ccaacaccaa agaaggcuca aacaucugcc ucacccgcac agaccgcggc     1020

ugguacugcg acaacgcggg cuccgucagc uucuuucccc aagcggaaac cugcaaaguc     1080

ugcagcaaca gagucuucug cgacacuaug aacucccuca cccuccccuc agaagucaac     1140

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaaucaugac cagcaaaacu     1200

gacgucuccu cguccgucau caccucacuc ggcgcaaucg ugagcugcua cggcaaaacc     1260

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa cauucagcaa cggcugcgac     1320

uacgucucga acaaaggagu cgacaccgua ucagugggca acacccuaua cuacguaaac     1380

aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1440

cucgucuucc ccuccgacga guucgacgcc uccaucucuc aagucaacga gaaaaucaac     1500

caaucccuug ccuucauacg uaaaagcgac gaacuccuuc acaacguaaa cgccgggaaa     1560

uccaccacua acauaaugau caccaccauc aucaucguua ucauagucau ccuccucucu     1620

cucauagcag ucggccuacu ccuguacugc aaagcgcgcu aaggacuagu guccaccugu     1680

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1740

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1860

gagccaccag aauu                                                       1874


<210>  7348
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7348
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7349
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7349
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7350
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7350
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7351
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7351
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7352
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7352
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7353
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7353
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7354
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7354
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccucaaa      120

gcaaacgcaa uuacaaccau acuaaccgcu gucaccuuuu guuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacaugc uccgcaguau cuaaaggaua ccucagcgcg      240

uuaagaacag gaugguacac aucgguaaua accaucgaau uauccaacau aaaagaaaau      300

aaaugcaaug gaacagacgc aaaagucaaa uuaauuaaac aagaacuaga caaauauaaa      360

aacgcaguaa ccgaauuaca aaugcuaaug uguucaacac cagcaacagg aucaggauca      420

gcuauagcuu caggaguugc cguaugcaaa gugcuacacu uagaaggaga agugaauaaa      480

auaaaaucag cucuauuauc aacgaacaaa gccguaguau cucuaucaaa uggcguauca      540

guacucacau ucaaaguacu cgaccuaaaa aacuauauag auaaacaacu auuacccauc      600

cuaaauaaac aaagcugcuc uauaucaaac aucgaaacag uaauggaauu ucaacaaaaa      660

aacaacagac uacuagaaau aacccgagag uucucaguua augcaggagu aacaacacca      720

gucucaacau acaugcucac aaacucagaa cuccuaucac uaauaaauga caugccaaua      780

acaaacgacc aaaaaaaacu caugucuaac aacguccaaa uaguaagaca acaauccuac      840

agcauaaugu guauaauaaa agaagaaguu uuagcauacg ucguacaacu acccuuauau      900

ggcguaauag auacaccaug cuggaaacuc cauaccucac cucuauguac aacaaauacc      960

aaagaagguu cuaauauaug ccuaacacga acugaccgag gaugguacug ugacaacgca     1020

ggaucagucu cuuucuuucc acaagcagaa accugcaaag uaugcaguaa ccgcguauuu     1080

ugcgacacaa ugaacucccu aaccuuacca ucagaaguaa acuuauguaa cguagacaua     1140

uucaauccaa aauaugacug caaaauaaug acaucaaaaa cagacguaag cucaucagua     1200

auaacuucac uaggcgcaau uguaucaugc uauggaaaaa ccaaauguac cgcauccaac     1260

aaaaauaaag gaauaauaaa aaccuucucu aacggaugcg acuacguauc aaacaaaggu     1320

guagauacag uuucuguagg aaacacacuc uacuauguaa auaaacaaga aggaaaauca     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cacuuguauu uccaucugau     1440

gaauuugaug caagcauauc acaaguaaac gaaaaaauaa accaaucucu agccuuuaua     1500

cgaaaaagcg acgaauuacu acauaacguc aacgcuggaa aaucaacaac aaacauaaug     1560

auaacaacaa uaauaauagu aauaauaguc auccuauuau cacuaaucgc cguaggacua     1620

cuccuauacu gcaaagcuag auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7355
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7355
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacuau ccucacagca gucacuuucu gcuucgccuc aggacaaaac      180

auaaccgaag aguucuacca auccacaugc uccgccgucu ccaaaggcua ccucucagcg      240

cuccgcaccg gcugguacac auccgucauc accaucgaac uaagcaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaaguuaaa cucaucaagc aagaacucga caaauacaaa      360

aacgcaguca cagaacuuca aaugcucaug ugcuccacac ccgccacagg uucuggcuca      420

gcaaucgcaa gcggcgucgc cguaugcaaa guccuucacc ucgaaggcga agucaacaaa      480

aucaaauccg cccuccucuc caccaauaaa gcugucgucu cacucuccaa cggcgucagc      540

guccucacau ucaaaguccu cgaccucaaa aacuacauag acaagcaacu ccucccgaua      600

cucaacaaac aaagcugcuc uaucuccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaucguc uccucgaaau cacccgcgag uucucaguaa acgccggggu caccacacca      720

gucuccaccu acaugcucac caacuccgaa cuccuuagcc ucauaaacga caugcccaua      780

accaacgacc aaaagaaacu caugagcaac aacguacaaa uaguccgaca acaauccuau      840

uccaucaugu guaucaucaa agaagaaguc cucgcauacg uaguccaacu cccccuauac      900

ggcguaaucg acaccccaug uuggaaacuc cacaccucac cacucuguac caccaacacc      960

aaagaaggcu caaacaucug ccucacccgc acagaccgcg gcugguacug cgacaacgcg     1020

ggcuccguca gcuucuuucc ccaagcggaa accugcaaag ucugcagcaa cagagucuuc     1080

ugcgacacua ugaacucccu cacccucccc ucagaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaaucaug accagcaaaa cugacgucuc cucguccguc     1200

aucaccucac ucggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aacauucagc aacggcugcg acuacgucuc gaacaaagga     1320

gucgacaccg uaucaguggg caacacccua uacuacguaa acaagcaaga aggcaaauca     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ucaagucaac gagaaaauca accaaucccu ugccuucaua     1500

cguaaaagcg acgaacuccu ucacaacgua aacgccggga aauccaccac uaacauaaug     1560

aucaccacca ucaucaucgu uaucauaguc auccuccucu cucucauagc agucggccua     1620

cuccuguacu gcaaagcgcg cuaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7356
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7356
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7357
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7357
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7358
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7358
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7359
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7359
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7360
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7360
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7361
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7361
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cugaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7362
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7362
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccucaaa gcaaacgcaa uuacaaccau acuaaccgcu      120

gucaccuuuu guuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacaugc      180

uccgcaguau cuaaaggaua ccucagcgcg uuaagaacag gaugguacac aucgguaaua      240

accaucgaau uauccaacau aaaagaaaau aaaugcaaug gaacagacgc aaaagucaaa      300

uuaauuaaac aagaacuaga caaauauaaa aacgcaguaa ccgaauuaca aaugcuaaug      360

uguucaacac cagcaacagg aucaggauca gcuauagcuu caggaguugc cguaugcaaa      420

gugcuacacu uagaaggaga agugaauaaa auaaaaucag cucuauuauc aacgaacaaa      480

gccguaguau cucuaucaaa uggcguauca guacucacau ucaaaguacu cgaccuaaaa      540

aacuauauag auaaacaacu auuacccauc cuaaauaaac aaagcugcuc uauaucaaac      600

aucgaaacag uaauggaauu ucaacaaaaa aacaacagac uacuagaaau aacccgagag      660

uucucaguua augcaggagu aacaacacca gucucaacau acaugcucac aaacucagaa      720

cuccuaucac uaauaaauga caugccaaua acaaacgacc aaaaaaaacu caugucuaac      780

aacguccaaa uaguaagaca acaauccuac agcauaaugu guauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu acccuuauau ggcguaauag auacaccaug cuggaaacuc      900

cauaccucac cucuauguac aacaaauacc aaagaagguu cuaauauaug ccuaacacga      960

acugaccgag gaugguacug ugacaacgca ggaucagucu cuuucuuucc acaagcagaa     1020

accugcaaag uaugcaguaa ccgcguauuu ugcgacacaa ugaacucccu aaccuuacca     1080

ucagaaguaa acuuauguaa cguagacaua uucaauccaa aauaugacug caaaauaaug     1140

acaucaaaaa cagacguaag cucaucagua auaacuucac uaggcgcaau uguaucaugc     1200

uauggaaaaa ccaaauguac cgcauccaac aaaaauaaag gaauaauaaa aaccuucucu     1260

aacggaugcg acuacguauc aaacaaaggu guagauacag uuucuguagg aaacacacuc     1320

uacuauguaa auaaacaaga aggaaaauca cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cacuuguauu uccaucugau gaauuugaug caagcauauc acaaguaaac     1440

gaaaaaauaa accaaucucu agccuuuaua cgaaaaagcg acgaauuacu acauaacguc     1500

aacgcuggaa aaucaacaac aaacauaaug auaacaacaa uaauaauagu aauaauaguc     1560

auccuauuau cacuaaucgc cguaggacua cuccuauacu gcaaagcuag auaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7363
<211>  1826
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7363
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacuau ccucacagca      120

gucacuuucu gcuucgccuc aggacaaaac auaaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaaaggcua ccucucagcg cuccgcaccg gcugguacac auccgucauc      240

accaucgaac uaagcaacau aaaagaaaac aaaugcaacg gcaccgacgc caaaguuaaa      300

cucaucaagc aagaacucga caaauacaaa aacgcaguca cagaacuuca aaugcucaug      360

ugcuccacac ccgccacagg uucuggcuca gcaaucgcaa gcggcgucgc cguaugcaaa      420

guccuucacc ucgaaggcga agucaacaaa aucaaauccg cccuccucuc caccaauaaa      480

gcugucgucu cacucuccaa cggcgucagc guccucacau ucaaaguccu cgaccucaaa      540

aacuacauag acaagcaacu ccucccgaua cucaacaaac aaagcugcuc uaucuccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaucguc uccucgaaau cacccgcgag      660

uucucaguaa acgccggggu caccacacca gucuccaccu acaugcucac caacuccgaa      720

cuccuuagcc ucauaaacga caugcccaua accaacgacc aaaagaaacu caugagcaac      780

aacguacaaa uaguccgaca acaauccuau uccaucaugu guaucaucaa agaagaaguc      840

cucgcauacg uaguccaacu cccccuauac ggcguaaucg acaccccaug uuggaaacuc      900

cacaccucac cacucuguac caccaacacc aaagaaggcu caaacaucug ccucacccgc      960

acagaccgcg gcugguacug cgacaacgcg ggcuccguca gcuucuuucc ccaagcggaa     1020

accugcaaag ucugcagcaa cagagucuuc ugcgacacua ugaacucccu cacccucccc     1080

ucagaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaaucaug     1140

accagcaaaa cugacgucuc cucguccguc aucaccucac ucggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aacauucagc     1260

aacggcugcg acuacgucuc gaacaaagga gucgacaccg uaucaguggg caacacccua     1320

uacuacguaa acaagcaaga aggcaaauca cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ucaagucaac     1440

gagaaaauca accaaucccu ugccuucaua cguaaaagcg acgaacuccu ucacaacgua     1500

aacgccggga aauccaccac uaacauaaug aucaccacca ucaucaucgu uaucauaguc     1560

auccuccucu cucucauagc agucggccua cuccuguacu gcaaagcgcg cuaaggacua     1620

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1680

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1800

aggcucuuuu cagagccacc agaauu                                          1826


<210>  7364
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7364
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7365
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7365
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7366
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7366
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7367
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7367
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7368
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7368
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7369
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7369
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7370
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7370
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu caaagcaaac gcaauuacaa ccauacuaac cgcugucacc      180

uuuuguuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac augcuccgca      240

guaucuaaag gauaccucag cgcguuaaga acaggauggu acacaucggu aauaaccauc      300

gaauuaucca acauaaaaga aaauaaaugc aauggaacag acgcaaaagu caaauuaauu      360

aaacaagaac uagacaaaua uaaaaacgca guaaccgaau uacaaaugcu aauguguuca      420

acaccagcaa caggaucagg aucagcuaua gcuucaggag uugccguaug caaagugcua      480

cacuuagaag gagaagugaa uaaaauaaaa ucagcucuau uaucaacgaa caaagccgua      540

guaucucuau caaauggcgu aucaguacuc acauucaaag uacucgaccu aaaaaacuau      600

auagauaaac aacuauuacc cauccuaaau aaacaaagcu gcucuauauc aaacaucgaa      660

acaguaaugg aauuucaaca aaaaaacaac agacuacuag aaauaacccg agaguucuca      720

guuaaugcag gaguaacaac accagucuca acauacaugc ucacaaacuc agaacuccua      780

ucacuaauaa augacaugcc aauaacaaac gaccaaaaaa aacucauguc uaacaacguc      840

caaauaguaa gacaacaauc cuacagcaua auguguauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuacccuu auauggcgua auagauacac caugcuggaa acuccauacc      960

ucaccucuau guacaacaaa uaccaaagaa gguucuaaua uaugccuaac acgaacugac     1020

cgaggauggu acugugacaa cgcaggauca gucucuuucu uuccacaagc agaaaccugc     1080

aaaguaugca guaaccgcgu auuuugcgac acaaugaacu cccuaaccuu accaucagaa     1140

guaaacuuau guaacguaga cauauucaau ccaaaauaug acugcaaaau aaugacauca     1200

aaaacagacg uaagcucauc aguaauaacu ucacuaggcg caauuguauc augcuaugga     1260

aaaaccaaau guaccgcauc caacaaaaau aaaggaauaa uaaaaaccuu cucuaacgga     1320

ugcgacuacg uaucaaacaa agguguagau acaguuucug uaggaaacac acucuacuau     1380

guaaauaaac aagaaggaaa aucacuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccacuug uauuuccauc ugaugaauuu gaugcaagca uaucacaagu aaacgaaaaa     1500

auaaaccaau cucuagccuu uauacgaaaa agcgacgaau uacuacauaa cgucaacgcu     1560

ggaaaaucaa caacaaacau aaugauaaca acaauaauaa uaguaauaau agucauccua     1620

uuaucacuaa ucgccguagg acuacuccua uacugcaaag cuagauaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7371
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7371
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca cuauccucac agcagucacu      180

uucugcuucg ccucaggaca aaacauaacc gaagaguucu accaauccac augcuccgcc      240

gucuccaaag gcuaccucuc agcgcuccgc accggcuggu acacauccgu caucaccauc      300

gaacuaagca acauaaaaga aaacaaaugc aacggcaccg acgccaaagu uaaacucauc      360

aagcaagaac ucgacaaaua caaaaacgca gucacagaac uucaaaugcu caugugcucc      420

acacccgcca cagguucugg cucagcaauc gcaagcggcg ucgccguaug caaaguccuu      480

caccucgaag gcgaagucaa caaaaucaaa uccgcccucc ucuccaccaa uaaagcuguc      540

gucucacucu ccaacggcgu cagcguccuc acauucaaag uccucgaccu caaaaacuac      600

auagacaagc aacuccuccc gauacucaac aaacaaagcu gcucuaucuc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaau cgucuccucg aaaucacccg cgaguucuca      720

guaaacgccg gggucaccac accagucucc accuacaugc ucaccaacuc cgaacuccuu      780

agccucauaa acgacaugcc cauaaccaac gaccaaaaga aacucaugag caacaacgua      840

caaauagucc gacaacaauc cuauuccauc auguguauca ucaaagaaga aguccucgca      900

uacguagucc aacucccccu auacggcgua aucgacaccc cauguuggaa acuccacacc      960

ucaccacucu guaccaccaa caccaaagaa ggcucaaaca ucugccucac ccgcacagac     1020

cgcggcuggu acugcgacaa cgcgggcucc gucagcuucu uuccccaagc ggaaaccugc     1080

aaagucugca gcaacagagu cuucugcgac acuaugaacu cccucacccu ccccucagaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau caugaccagc     1200

aaaacugacg ucuccucguc cgucaucacc ucacucggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaacauu cagcaacggc     1320

ugcgacuacg ucucgaacaa aggagucgac accguaucag ugggcaacac ccuauacuac     1380

guaaacaagc aagaaggcaa aucacucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucucaagu caacgagaaa     1500

aucaaccaau cccuugccuu cauacguaaa agcgacgaac uccuucacaa cguaaacgcc     1560

gggaaaucca ccacuaacau aaugaucacc accaucauca ucguuaucau agucauccuc     1620

cucucucuca uagcagucgg ccuacuccug uacugcaaag cgcgcuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7372
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7372
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7373
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7373
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7374
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7374
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7375
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7375
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7376
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7376
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7377
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7377
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7378
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7378
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccucaa agcaaacgca      120

auuacaacca uacuaaccgc ugucaccuuu uguuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacaug cuccgcagua ucuaaaggau accucagcgc guuaagaaca      240

ggaugguaca caucgguaau aaccaucgaa uuauccaaca uaaaagaaaa uaaaugcaau      300

ggaacagacg caaaagucaa auuaauuaaa caagaacuag acaaauauaa aaacgcagua      360

accgaauuac aaaugcuaau guguucaaca ccagcaacag gaucaggauc agcuauagcu      420

ucaggaguug ccguaugcaa agugcuacac uuagaaggag aagugaauaa aauaaaauca      480

gcucuauuau caacgaacaa agccguagua ucucuaucaa auggcguauc aguacucaca      540

uucaaaguac ucgaccuaaa aaacuauaua gauaaacaac uauuacccau ccuaaauaaa      600

caaagcugcu cuauaucaaa caucgaaaca guaauggaau uucaacaaaa aaacaacaga      660

cuacuagaaa uaacccgaga guucucaguu aaugcaggag uaacaacacc agucucaaca      720

uacaugcuca caaacucaga acuccuauca cuaauaaaug acaugccaau aacaaacgac      780

caaaaaaaac ucaugucuaa caacguccaa auaguaagac aacaauccua cagcauaaug      840

uguauaauaa aagaagaagu uuuagcauac gucguacaac uacccuuaua uggcguaaua      900

gauacaccau gcuggaaacu ccauaccuca ccucuaugua caacaaauac caaagaaggu      960

ucuaauauau gccuaacacg aacugaccga ggaugguacu gugacaacgc aggaucaguc     1020

ucuuucuuuc cacaagcaga aaccugcaaa guaugcagua accgcguauu uugcgacaca     1080

augaacuccc uaaccuuacc aucagaagua aacuuaugua acguagacau auucaaucca     1140

aaauaugacu gcaaaauaau gacaucaaaa acagacguaa gcucaucagu aauaacuuca     1200

cuaggcgcaa uuguaucaug cuauggaaaa accaaaugua ccgcauccaa caaaaauaaa     1260

ggaauaauaa aaaccuucuc uaacggaugc gacuacguau caaacaaagg uguagauaca     1320

guuucuguag gaaacacacu cuacuaugua aauaaacaag aaggaaaauc acuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccacuuguau uuccaucuga ugaauuugau     1440

gcaagcauau cacaaguaaa cgaaaaaaua aaccaaucuc uagccuuuau acgaaaaagc     1500

gacgaauuac uacauaacgu caacgcugga aaaucaacaa caaacauaau gauaacaaca     1560

auaauaauag uaauaauagu cauccuauua ucacuaaucg ccguaggacu acuccuauac     1620

ugcaaagcua gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7379
<211>  1847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7379
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacua uccucacagc agucacuuuc ugcuucgccu caggacaaaa cauaaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaaaggcu accucucagc gcuccgcacc      240

ggcugguaca cauccgucau caccaucgaa cuaagcaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaaguuaa acucaucaag caagaacucg acaaauacaa aaacgcaguc      360

acagaacuuc aaaugcucau gugcuccaca cccgccacag guucuggcuc agcaaucgca      420

agcggcgucg ccguaugcaa aguccuucac cucgaaggcg aagucaacaa aaucaaaucc      480

gcccuccucu ccaccaauaa agcugucguc ucacucucca acggcgucag cguccucaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaagcaac uccucccgau acucaacaaa      600

caaagcugcu cuaucuccaa caucgaaacc gucauggagu uccaacagaa aaacaaucgu      660

cuccucgaaa ucacccgcga guucucagua aacgccgggg ucaccacacc agucuccacc      720

uacaugcuca ccaacuccga acuccuuagc cucauaaacg acaugcccau aaccaacgac      780

caaaagaaac ucaugagcaa caacguacaa auaguccgac aacaauccua uuccaucaug      840

uguaucauca aagaagaagu ccucgcauac guaguccaac ucccccuaua cggcguaauc      900

gacaccccau guuggaaacu ccacaccuca ccacucugua ccaccaacac caaagaaggc      960

ucaaacaucu gccucacccg cacagaccgc ggcugguacu gcgacaacgc gggcuccguc     1020

agcuucuuuc cccaagcgga aaccugcaaa gucugcagca acagagucuu cugcgacacu     1080

augaacuccc ucacccuccc cucagaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaaucau gaccagcaaa acugacgucu ccucguccgu caucaccuca     1200

cucggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaacauucag caacggcugc gacuacgucu cgaacaaagg agucgacacc     1320

guaucagugg gcaacacccu auacuacgua aacaagcaag aaggcaaauc acucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cucaagucaa cgagaaaauc aaccaauccc uugccuucau acguaaaagc     1500

gacgaacucc uucacaacgu aaacgccggg aaauccacca cuaacauaau gaucaccacc     1560

aucaucaucg uuaucauagu cauccuccuc ucucucauag cagucggccu acuccuguac     1620

ugcaaagcgc gcuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1680

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1800

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1847


<210>  7380
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7380
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7381
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7381
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7382
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7382
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7383
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7383
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7384
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7384
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7385
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7385
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7386
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7386
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccucaa agcaaacgca      120

auuacaacca uacuaaccgc ugucaccuuu uguuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacaug cuccgcagua ucuaaaggau accucagcgc guuaagaaca      240

ggaugguaca caucgguaau aaccaucgaa uuauccaaca uaaaagaaaa uaaaugcaau      300

ggaacagacg caaaagucaa auuaauuaaa caagaacuag acaaauauaa aaacgcagua      360

accgaauuac aaaugcuaau guguucaaca ccagcaacag gaucaggauc agcuauagcu      420

ucaggaguug ccguaugcaa agugcuacac uuagaaggag aagugaauaa aauaaaauca      480

gcucuauuau caacgaacaa agccguagua ucucuaucaa auggcguauc aguacucaca      540

uucaaaguac ucgaccuaaa aaacuauaua gauaaacaac uauuacccau ccuaaauaaa      600

caaagcugcu cuauaucaaa caucgaaaca guaauggaau uucaacaaaa aaacaacaga      660

cuacuagaaa uaacccgaga guucucaguu aaugcaggag uaacaacacc agucucaaca      720

uacaugcuca caaacucaga acuccuauca cuaauaaaug acaugccaau aacaaacgac      780

caaaaaaaac ucaugucuaa caacguccaa auaguaagac aacaauccua cagcauaaug      840

uguauaauaa aagaagaagu uuuagcauac gucguacaac uacccuuaua uggcguaaua      900

gauacaccau gcuggaaacu ccauaccuca ccucuaugua caacaaauac caaagaaggu      960

ucuaauauau gccuaacacg aacugaccga ggaugguacu gugacaacgc aggaucaguc     1020

ucuuucuuuc cacaagcaga aaccugcaaa guaugcagua accgcguauu uugcgacaca     1080

augaacuccc uaaccuuacc aucagaagua aacuuaugua acguagacau auucaaucca     1140

aaauaugacu gcaaaauaau gacaucaaaa acagacguaa gcucaucagu aauaacuuca     1200

cuaggcgcaa uuguaucaug cuauggaaaa accaaaugua ccgcauccaa caaaaauaaa     1260

ggaauaauaa aaaccuucuc uaacggaugc gacuacguau caaacaaagg uguagauaca     1320

guuucuguag gaaacacacu cuacuaugua aauaaacaag aaggaaaauc acuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccacuuguau uuccaucuga ugaauuugau     1440

gcaagcauau cacaaguaaa cgaaaaaaua aaccaaucuc uagccuuuau acgaaaaagc     1500

gacgaauuac uacauaacgu caacgcugga aaaucaacaa caaacauaau gauaacaaca     1560

auaauaauag uaauaauagu cauccuauua ucacuaaucg ccguaggacu acuccuauac     1620

ugcaaagcua gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7387
<211>  1914
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7387
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacua uccucacagc agucacuuuc ugcuucgccu caggacaaaa cauaaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaaaggcu accucucagc gcuccgcacc      240

ggcugguaca cauccgucau caccaucgaa cuaagcaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaaguuaa acucaucaag caagaacucg acaaauacaa aaacgcaguc      360

acagaacuuc aaaugcucau gugcuccaca cccgccacag guucuggcuc agcaaucgca      420

agcggcgucg ccguaugcaa aguccuucac cucgaaggcg aagucaacaa aaucaaaucc      480

gcccuccucu ccaccaauaa agcugucguc ucacucucca acggcgucag cguccucaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaagcaac uccucccgau acucaacaaa      600

caaagcugcu cuaucuccaa caucgaaacc gucauggagu uccaacagaa aaacaaucgu      660

cuccucgaaa ucacccgcga guucucagua aacgccgggg ucaccacacc agucuccacc      720

uacaugcuca ccaacuccga acuccuuagc cucauaaacg acaugcccau aaccaacgac      780

caaaagaaac ucaugagcaa caacguacaa auaguccgac aacaauccua uuccaucaug      840

uguaucauca aagaagaagu ccucgcauac guaguccaac ucccccuaua cggcguaauc      900

gacaccccau guuggaaacu ccacaccuca ccacucugua ccaccaacac caaagaaggc      960

ucaaacaucu gccucacccg cacagaccgc ggcugguacu gcgacaacgc gggcuccguc     1020

agcuucuuuc cccaagcgga aaccugcaaa gucugcagca acagagucuu cugcgacacu     1080

augaacuccc ucacccuccc cucagaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaaucau gaccagcaaa acugacgucu ccucguccgu caucaccuca     1200

cucggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaacauucag caacggcugc gacuacgucu cgaacaaagg agucgacacc     1320

guaucagugg gcaacacccu auacuacgua aacaagcaag aaggcaaauc acucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cucaagucaa cgagaaaauc aaccaauccc uugccuucau acguaaaagc     1500

gacgaacucc uucacaacgu aaacgccggg aaauccacca cuaacauaau gaucaccacc     1560

aucaucaucg uuaucauagu cauccuccuc ucucucauag cagucggccu acuccuguac     1620

ugcaaagcgc gcuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1680

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1740

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1860

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1914


<210>  7388
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7388
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7389
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7389
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7390
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7390
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7391
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7391
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7392
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7392
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7393
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7393
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7394
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7394
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccucaa agcaaacgca      120

auuacaacca uacuaaccgc ugucaccuuu uguuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacaug cuccgcagua ucuaaaggau accucagcgc guuaagaaca      240

ggaugguaca caucgguaau aaccaucgaa uuauccaaca uaaaagaaaa uaaaugcaau      300

ggaacagacg caaaagucaa auuaauuaaa caagaacuag acaaauauaa aaacgcagua      360

accgaauuac aaaugcuaau guguucaaca ccagcaacag gaucaggauc agcuauagcu      420

ucaggaguug ccguaugcaa agugcuacac uuagaaggag aagugaauaa aauaaaauca      480

gcucuauuau caacgaacaa agccguagua ucucuaucaa auggcguauc aguacucaca      540

uucaaaguac ucgaccuaaa aaacuauaua gauaaacaac uauuacccau ccuaaauaaa      600

caaagcugcu cuauaucaaa caucgaaaca guaauggaau uucaacaaaa aaacaacaga      660

cuacuagaaa uaacccgaga guucucaguu aaugcaggag uaacaacacc agucucaaca      720

uacaugcuca caaacucaga acuccuauca cuaauaaaug acaugccaau aacaaacgac      780

caaaaaaaac ucaugucuaa caacguccaa auaguaagac aacaauccua cagcauaaug      840

uguauaauaa aagaagaagu uuuagcauac gucguacaac uacccuuaua uggcguaaua      900

gauacaccau gcuggaaacu ccauaccuca ccucuaugua caacaaauac caaagaaggu      960

ucuaauauau gccuaacacg aacugaccga ggaugguacu gugacaacgc aggaucaguc     1020

ucuuucuuuc cacaagcaga aaccugcaaa guaugcagua accgcguauu uugcgacaca     1080

augaacuccc uaaccuuacc aucagaagua aacuuaugua acguagacau auucaaucca     1140

aaauaugacu gcaaaauaau gacaucaaaa acagacguaa gcucaucagu aauaacuuca     1200

cuaggcgcaa uuguaucaug cuauggaaaa accaaaugua ccgcauccaa caaaaauaaa     1260

ggaauaauaa aaaccuucuc uaacggaugc gacuacguau caaacaaagg uguagauaca     1320

guuucuguag gaaacacacu cuacuaugua aauaaacaag aaggaaaauc acuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccacuuguau uuccaucuga ugaauuugau     1440

gcaagcauau cacaaguaaa cgaaaaaaua aaccaaucuc uagccuuuau acgaaaaagc     1500

gacgaauuac uacauaacgu caacgcugga aaaucaacaa caaacauaau gauaacaaca     1560

auaauaauag uaauaauagu cauccuauua ucacuaaucg ccguaggacu acuccuauac     1620

ugcaaagcua gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7395
<211>  2130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7395
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacua uccucacagc agucacuuuc ugcuucgccu caggacaaaa cauaaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaaaggcu accucucagc gcuccgcacc      240

ggcugguaca cauccgucau caccaucgaa cuaagcaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaaguuaa acucaucaag caagaacucg acaaauacaa aaacgcaguc      360

acagaacuuc aaaugcucau gugcuccaca cccgccacag guucuggcuc agcaaucgca      420

agcggcgucg ccguaugcaa aguccuucac cucgaaggcg aagucaacaa aaucaaaucc      480

gcccuccucu ccaccaauaa agcugucguc ucacucucca acggcgucag cguccucaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaagcaac uccucccgau acucaacaaa      600

caaagcugcu cuaucuccaa caucgaaacc gucauggagu uccaacagaa aaacaaucgu      660

cuccucgaaa ucacccgcga guucucagua aacgccgggg ucaccacacc agucuccacc      720

uacaugcuca ccaacuccga acuccuuagc cucauaaacg acaugcccau aaccaacgac      780

caaaagaaac ucaugagcaa caacguacaa auaguccgac aacaauccua uuccaucaug      840

uguaucauca aagaagaagu ccucgcauac guaguccaac ucccccuaua cggcguaauc      900

gacaccccau guuggaaacu ccacaccuca ccacucugua ccaccaacac caaagaaggc      960

ucaaacaucu gccucacccg cacagaccgc ggcugguacu gcgacaacgc gggcuccguc     1020

agcuucuuuc cccaagcgga aaccugcaaa gucugcagca acagagucuu cugcgacacu     1080

augaacuccc ucacccuccc cucagaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaaucau gaccagcaaa acugacgucu ccucguccgu caucaccuca     1200

cucggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaacauucag caacggcugc gacuacgucu cgaacaaagg agucgacacc     1320

guaucagugg gcaacacccu auacuacgua aacaagcaag aaggcaaauc acucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cucaagucaa cgagaaaauc aaccaauccc uugccuucau acguaaaagc     1500

gacgaacucc uucacaacgu aaacgccggg aaauccacca cuaacauaau gaucaccacc     1560

aucaucaucg uuaucauagu cauccuccuc ucucucauag cagucggccu acuccuguac     1620

ugcaaagcgc gcuaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1680

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1740

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1800

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1860

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1920

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1980

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     2100

ccaaaggcuc uuuucagagc caccagaauu                                      2130


<210>  7396
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7396
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcugau gugcuccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucucca acggcgucag cgugcugacc      540

uucaaggugc uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacg gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc      900

gacacccccu gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg      960

uccaacaucu gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc     1020

uccuucuucc cgcaggccga gaccugcaag gugugcagca accgcguguu cugcgacacc     1080

augaacuccc ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc     1200

cugggggcca ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagaacaag     1260

gggaucauca agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

guguccgucg ggaacacccu guacuacgug aacaagcagg agggcaagag ccucuacgug     1380

aagggggagc ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac     1440

gcgagcaucu cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc     1500

gacgagcugc uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac     1620

ugcaaggccc ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7397
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7397
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucagcgc ccugcgcacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggagcugc agaugcucau gugcuccacc cccgccaccg gcagcggguc cgccaucgcc      420

agcggcgugg cggugugcaa gguccugcac cuggagggcg aggugaacaa gaucaagucc      480

gcccuccuga gcaccaacaa ggccgugguc ucccugagca acgggguguc cgugcucacg      540

uucaaggucc uggaccugaa gaacuacauc gacaagcagc uccugccgau ccugaacaag      600

cagagcugcu ccaucagcaa caucgagacc gugauggagu uccagcagaa gaacaaccgg      660

cuccuggaga ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc      720

uacaugcuga ccaacagcga gcuccugucc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac gugguccagc ugccccucua cggggugauc      900

gacacgccgu gcuggaagcu gcacaccagc ccccugugca ccaccaacac gaaggagggc      960

agcaacaucu gccucacccg caccgaccgg gggugguacu gcgacaacgc gggcuccgug     1020

agcuucuucc cccaggccga gaccugcaag gucugcucca accgcguguu cugcgacacg     1080

augaacagcc ugacccugcc cuccgagguc aaccucugca acguggacau cuucaacccg     1140

aaguacgacu gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc     1200

cugggcgcca ucguguccug cuacgggaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucuc caacgggugc gacuacguga gcaacaaggg cgucgacacg     1320

gugagcgugg gcaacacccu guacuacguc aacaagcagg aggggaaguc ccucuacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccuccauca gccaggucaa cgagaagauc aaccaguccc uggcguucau ccggaagucc     1500

gacgagcucc ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg     1560

aucaucaucg ugaucaucgu cauccugcuc agccugaucg ccgugggccu gcuccuguac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7398
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7398
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucuccgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgagcucc agaugcucau gugcuccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucucca acggcgucuc cguccucacc      540

uucaaggucc ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag      600

caguccugcu ccaucuccaa caucgagacc gucauggagu uccagcagaa gaacaaccgc      660

cuccucgaga ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc      720

uacaugcuca ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac      780

cagaagaagc ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug      840

ugcaucauca aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc      900

gacacccccu gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc      960

uccaacaucu gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc     1020

uccuucuucc cccaggccga gaccugcaag gucugcucca accgcgucuu cugcgacacc     1080

augaacuccc ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc     1200

cucggcgcca ucgucuccug cuacggcaag accaagugca ccgccuccaa caagaacaag     1260

ggcaucauca agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc     1320

gucuccgucg gcaacacccu cuacuacguc aacaagcagg agggcaaguc ccucuacguc     1380

aagggcgagc ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc     1500

gacgagcucc uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc     1560

aucaucaucg ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac     1620

ugcaaggccc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7399
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7399
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugagugc uuuaagaacu      240

ggaugguaca ccagcguuau uacaaucgaa cuguccaaca uuaaggagaa uaaaugcaac      300

gguaccgacg ccaaggugaa acuaaucaag caggaacucg auaaguauaa aaaugcagua      360

acugagcugc agaugcuuau guguucuaca cccgccaccg gcucgggguc agcuauagca      420

agcggagugg ccgucugcaa ggugcugcac uuggagggcg aaguuaacaa aaucaagagu      480

gcucuccugu ccacgaauaa agccgugguc ucucugagca acgguguguc cguacucacu      540

uuuaagguuu uagaccugaa gaauuacauu gauaaacagc uuuugccuau ccugaacaag      600

caaucaugua guauuagcaa uaucgagacc gugauggagu uccagcagaa aaacaauagg      660

cuacucgaaa uaacacggga guuuucuguc aacgcggggg ugacuacccc aguguccaca      720

uauaugcuga ccaauucaga acuucugagc uugauuaacg acaugccgau cacgaacgau      780

cagaagaaac ucaugaguaa uaacguccaa auuguucgcc agcagucuua cuccaucaug      840

ugcaucauua aggaggaagu gcuggcauau guagugcagu uaccccugua cggagucaua      900

gacacuccuu guuggaaacu ccauacaagc ccacuuugca ccacuaauac aaaggagggc      960

ucgaacaucu gucugacccg aacggaucgu ggcugguacu gcgacaaugc cgggucugug     1020

uccuucuuuc cccaagcuga aaccuguaag guuugcucaa acagaguguu cugcgauaca     1080

augaauaguu ugacucuacc uagcgagguc aaccugugua auguggacau uuuuaaccca     1140

aaauaugauu gcaagaucau gaccuccaaa acagacguau cuagcucagu uauaacuagc     1200

cucggagcca uuguguccug uuacgguaag accaaaugca cagcaagcaa uaagaacaag     1260

ggcaucauca aaaccuucuc uaaugggugu gauuaugucu caaacaaggg aguggacacu     1320

gucagugugg gcaauacgcu guacuauguu aacaaacagg aggguaagag ccuuuacgug     1380

aaaggggaac ccauuaucaa cuuuuaugac ccucugguau ucccauccga ugaguuugac     1440

gcuucuauuu cgcaggucaa ugaaaagaua aaccaaaguu uggccuucau caggaagucc     1500

gaugagcucc ugcacaaugu gaacgcggga aaaucaacaa ccaauauuau gaucacuacc     1560

aucauuauag uuaucauugu gaucuuacug agucuaauug ccgucggccu ccugcuuuac     1620

ugcaaggcac ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7400
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7400
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugagcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagaa caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgagcugc agaugcugau gugcagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagca acggcgugag cgugcugacc      540

uucaaggugc uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag      600

cagagcugca gcaucagcaa caucgagacc gugauggagu uccagcagaa gaacaacaga      660

cugcuggaga ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc      720

uacaugcuga ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac      780

cagaagaagc ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug      840

ugcaucauca aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc      900

gacacccccu gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc      960

agcaacaucu gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug     1020

agcuucuucc cccaggccga gaccugcaag gugugcagca acagaguguu cugcgacacc     1080

augaacagcc ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc     1140

aaguacgacu gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc     1200

cugggcgcca ucgugagcug cuacggcaag accaagugca ccgccagcaa caagaacaag     1260

ggcaucauca agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc     1320

gugagcgugg gcaacacccu guacuacgug aacaagcagg agggcaagag ccuguacgug     1380

aagggcgagc ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac     1440

gccagcauca gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc     1500

gacgagcugc ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc     1560

aucaucaucg ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac     1620

ugcaaggcca gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7401
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7401
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucuguccgc ccucagaaca      240

ggaugguaca ccucuguuau cacaauugaa cugagcaaca ucaaggagaa uaaaugcaac      300

ggcaccgacg ccaaggugaa acuuaucaag caggaacugg auaaguauaa aaaugcugug      360

acggagcucc agaugcugau guguuccacc cccgccacag ggucuggaag cgcuauugcc      420

uccggcgucg cggugugcaa gguucugcac cucgaggggg aagugaacaa aaucaagagc      480

gcccugcuuu cuaccaauaa agcugucgug ucccugagca acggaguuuc ugugcucaca      540

uuuaaggucc uggaccuuaa gaauuacauu gauaaacagc ugcucccuau ccugaacaag      600

caauccugua gcauuucuaa uaucgagacc gugauggagu uccagcagaa aaacaaucgg      660

cugcucgaaa uuacgcgcga guuuuccgug aacgccggcg ucacaacccc gguuagcaca      720

uauaugcuga ccaauuccga acuucugucu cucaucaacg acaugcccau caccaacgau      780

cagaagaaac ugaugagcaa uaacgugcaa auugugagac agcaguccua cagcaucaug      840

ugcauuauca aggaggaagu ccuugcuuau gugguucagc ugccucucua cggcgugauu      900

gacacacccu guuggaaacu gcauacgucu ccucugugca ccacaaauac caaggagggg      960

uccaacaucu gucucacacg gaccgaucgc ggaugguacu gcgacaaugc cggcagcguc     1020

ucuuucuuuc cccaagcgga aacguguaag gugugcagca acagaguuuu cugcgauaca     1080

augaacuccc ugacccuucc uucugaggug aaucugugua augucgacau cuuuaacccg     1140

aaauaugauu gcaagauuau gaccagcaaa acagacgugu ccagcucugu caucaccucc     1200

cucggggcca uugugagcug uuacggaaag acaaaaugca cggcuucuaa uaagaacaag     1260

ggcaucauua aaaccuucuc caaugggugu gauuauguua gcaacaaggg aguggacaca     1320

gucuccgugg gcaauacccu guacuauguu aacaaacagg agggcaaguc ucuuuacgug     1380

aaaggggaac ccaucaucaa cuuuuaugac ccucuggucu uccccagcga ugaguuugac     1440

gccuccauuu cucaggugaa ugaaaagauc aaccaaagcc ucgcuuucau ucggaagucc     1500

gaugagcugc ugcacaaugu gaacgccgga aaaagcacaa ccaauaucau gauuacgacc     1560

aucauuaucg uuaucauugu cauccuccug ucucuuauug ccgugggccu gcuccuguac     1620

ugcaaggcuc gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7402
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7402
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaauuac uaauccucaa agcaaacgca      120

auuacaacca uacuaaccgc ugucaccuuu uguuuugccu caggacaaaa cauaacugaa      180

gaauuuuacc aaucaacaug cuccgcagua ucuaaaggau accucagcgc guuaagaaca      240

ggaugguaca caucgguaau aaccaucgaa uuauccaaca uaaaagaaaa uaaaugcaau      300

ggaacagacg caaaagucaa auuaauuaaa caagaacuag acaaauauaa aaacgcagua      360

accgaauuac aaaugcuaau guguucaaca ccagcaacag gaucaggauc agcuauagcu      420

ucaggaguug ccguaugcaa agugcuacac uuagaaggag aagugaauaa aauaaaauca      480

gcucuauuau caacgaacaa agccguagua ucucuaucaa auggcguauc aguacucaca      540

uucaaaguac ucgaccuaaa aaacuauaua gauaaacaac uauuacccau ccuaaauaaa      600

caaagcugcu cuauaucaaa caucgaaaca guaauggaau uucaacaaaa aaacaacaga      660

cuacuagaaa uaacccgaga guucucaguu aaugcaggag uaacaacacc agucucaaca      720

uacaugcuca caaacucaga acuccuauca cuaauaaaug acaugccaau aacaaacgac      780

caaaaaaaac ucaugucuaa caacguccaa auaguaagac aacaauccua cagcauaaug      840

uguauaauaa aagaagaagu uuuagcauac gucguacaac uacccuuaua uggcguaaua      900

gauacaccau gcuggaaacu ccauaccuca ccucuaugua caacaaauac caaagaaggu      960

ucuaauauau gccuaacacg aacugaccga ggaugguacu gugacaacgc aggaucaguc     1020

ucuuucuuuc cacaagcaga aaccugcaaa guaugcagua accgcguauu uugcgacaca     1080

augaacuccc uaaccuuacc aucagaagua aacuuaugua acguagacau auucaaucca     1140

aaauaugacu gcaaaauaau gacaucaaaa acagacguaa gcucaucagu aauaacuuca     1200

cuaggcgcaa uuguaucaug cuauggaaaa accaaaugua ccgcauccaa caaaaauaaa     1260

ggaauaauaa aaaccuucuc uaacggaugc gacuacguau caaacaaagg uguagauaca     1320

guuucuguag gaaacacacu cuacuaugua aauaaacaag aaggaaaauc acuauacgua     1380

aaaggagaac caauaauaaa cuucuaugac ccacuuguau uuccaucuga ugaauuugau     1440

gcaagcauau cacaaguaaa cgaaaaaaua aaccaaucuc uagccuuuau acgaaaaagc     1500

gacgaauuac uacauaacgu caacgcugga aaaucaacaa caaacauaau gauaacaaca     1560

auaauaauag uaauaauagu cauccuauua ucacuaaucg ccguaggacu acuccuauac     1620

ugcaaagcua gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7403
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7403
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

auaaccacua uccucacagc agucacuuuc ugcuucgccu caggacaaaa cauaaccgaa      180

gaguucuacc aauccacaug cuccgccguc uccaaaggcu accucucagc gcuccgcacc      240

ggcugguaca cauccgucau caccaucgaa cuaagcaaca uaaaagaaaa caaaugcaac      300

ggcaccgacg ccaaaguuaa acucaucaag caagaacucg acaaauacaa aaacgcaguc      360

acagaacuuc aaaugcucau gugcuccaca cccgccacag guucuggcuc agcaaucgca      420

agcggcgucg ccguaugcaa aguccuucac cucgaaggcg aagucaacaa aaucaaaucc      480

gcccuccucu ccaccaauaa agcugucguc ucacucucca acggcgucag cguccucaca      540

uucaaagucc ucgaccucaa aaacuacaua gacaagcaac uccucccgau acucaacaaa      600

caaagcugcu cuaucuccaa caucgaaacc gucauggagu uccaacagaa aaacaaucgu      660

cuccucgaaa ucacccgcga guucucagua aacgccgggg ucaccacacc agucuccacc      720

uacaugcuca ccaacuccga acuccuuagc cucauaaacg acaugcccau aaccaacgac      780

caaaagaaac ucaugagcaa caacguacaa auaguccgac aacaauccua uuccaucaug      840

uguaucauca aagaagaagu ccucgcauac guaguccaac ucccccuaua cggcguaauc      900

gacaccccau guuggaaacu ccacaccuca ccacucugua ccaccaacac caaagaaggc      960

ucaaacaucu gccucacccg cacagaccgc ggcugguacu gcgacaacgc gggcuccguc     1020

agcuucuuuc cccaagcgga aaccugcaaa gucugcagca acagagucuu cugcgacacu     1080

augaacuccc ucacccuccc cucagaaguc aaccucugca acgucgacau cuucaacccg     1140

aaauacgacu gcaaaaucau gaccagcaaa acugacgucu ccucguccgu caucaccuca     1200

cucggcgcaa ucgugagcug cuacggcaaa accaaaugca ccgccuccaa caaaaacaaa     1260

ggcaucauaa aaacauucag caacggcugc gacuacgucu cgaacaaagg agucgacacc     1320

guaucagugg gcaacacccu auacuacgua aacaagcaag aaggcaaauc acucuacgua     1380

aaaggcgaac ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac     1440

gccuccaucu cucaagucaa cgagaaaauc aaccaauccc uugccuucau acguaaaagc     1500

gacgaacucc uucacaacgu aaacgccggg aaauccacca cuaacauaau gaucaccacc     1560

aucaucaucg uuaucauagu cauccuccuc ucucucauag cagucggccu acuccuguac     1620

ugcaaagcgc gcuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1680

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1740

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  7404
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7404
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7405
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7405
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7406
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7406
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7407
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7407
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7408
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7408
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7409
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7409
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7410
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7410
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccucaaagc aaacgcaauu acaaccauac      120

uaaccgcugu caccuuuugu uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacaugcuc cgcaguaucu aaaggauacc ucagcgcguu aagaacagga ugguacacau      240

cgguaauaac caucgaauua uccaacauaa aagaaaauaa augcaaugga acagacgcaa      300

aagucaaauu aauuaaacaa gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa      360

ugcuaaugug uucaacacca gcaacaggau caggaucagc uauagcuuca ggaguugccg      420

uaugcaaagu gcuacacuua gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa      480

cgaacaaagc cguaguaucu cuaucaaaug gcguaucagu acucacauuc aaaguacucg      540

accuaaaaaa cuauauagau aaacaacuau uacccauccu aaauaaacaa agcugcucua      600

uaucaaacau cgaaacagua auggaauuuc aacaaaaaaa caacagacua cuagaaauaa      660

cccgagaguu cucaguuaau gcaggaguaa caacaccagu cucaacauac augcucacaa      720

acucagaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa cguccaaaua guaagacaac aauccuacag cauaaugugu auaauaaaag      840

aagaaguuuu agcauacguc guacaacuac ccuuauaugg cguaauagau acaccaugcu      900

ggaaacucca uaccucaccu cuauguacaa caaauaccaa agaagguucu aauauaugcc      960

uaacacgaac ugaccgagga ugguacugug acaacgcagg aucagucucu uucuuuccac     1020

aagcagaaac cugcaaagua ugcaguaacc gcguauuuug cgacacaaug aacucccuaa     1080

ccuuaccauc agaaguaaac uuauguaacg uagacauauu caauccaaaa uaugacugca     1140

aaauaaugac aucaaaaaca gacguaagcu caucaguaau aacuucacua ggcgcaauug     1200

uaucaugcua uggaaaaacc aaauguaccg cauccaacaa aaauaaagga auaauaaaaa     1260

ccuucucuaa cggaugcgac uacguaucaa acaaaggugu agauacaguu ucuguaggaa     1320

acacacucua cuauguaaau aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca cuuguauuuc caucugauga auuugaugca agcauaucac     1440

aaguaaacga aaaaauaaac caaucucuag ccuuuauacg aaaaagcgac gaauuacuac     1500

auaacgucaa cgcuggaaaa ucaacaacaa acauaaugau aacaacaaua auaauaguaa     1560

uaauagucau ccuauuauca cuaaucgccg uaggacuacu ccuauacugc aaagcuagau     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7411
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7411
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacuaucc      120

ucacagcagu cacuuucugc uucgccucag gacaaaacau aaccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau      240

ccgucaucac caucgaacua agcaacauaa aagaaaacaa augcaacggc accgacgcca      300

aaguuaaacu caucaagcaa gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa      360

ugcucaugug cuccacaccc gccacagguu cuggcucagc aaucgcaagc ggcgucgccg      420

uaugcaaagu ccuucaccuc gaaggcgaag ucaacaaaau caaauccgcc cuccucucca      480

ccaauaaagc ugucgucuca cucuccaacg gcgucagcgu ccucacauuc aaaguccucg      540

accucaaaaa cuacauagac aagcaacucc ucccgauacu caacaaacaa agcugcucua      600

ucuccaacau cgaaaccguc auggaguucc aacagaaaaa caaucgucuc cucgaaauca      660

cccgcgaguu cucaguaaac gccgggguca ccacaccagu cuccaccuac augcucacca      720

acuccgaacu ccuuagccuc auaaacgaca ugcccauaac caacgaccaa aagaaacuca      780

ugagcaacaa cguacaaaua guccgacaac aauccuauuc caucaugugu aucaucaaag      840

aagaaguccu cgcauacgua guccaacucc cccuauacgg cguaaucgac accccauguu      900

ggaaacucca caccucacca cucuguacca ccaacaccaa agaaggcuca aacaucugcc      960

ucacccgcac agaccgcggc ugguacugcg acaacgcggg cuccgucagc uucuuucccc     1020

aagcggaaac cugcaaaguc ugcagcaaca gagucuucug cgacacuaug aacucccuca     1080

cccuccccuc agaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaaucaugac cagcaaaacu gacgucuccu cguccgucau caccucacuc ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

cauucagcaa cggcugcgac uacgucucga acaaaggagu cgacaccgua ucagugggca     1320

acacccuaua cuacguaaac aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucucuc     1440

aagucaacga gaaaaucaac caaucccuug ccuucauacg uaaaagcgac gaacuccuuc     1500

acaacguaaa cgccgggaaa uccaccacua acauaaugau caccaccauc aucaucguua     1560

ucauagucau ccuccucucu cucauagcag ucggccuacu ccuguacugc aaagcgcgcu     1620

aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc ccaggauggu     1680

gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug acuuaccugc     1740

uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  7412
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7412
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcugaugug cuccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg      540

accucaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcucca      600

ucagcaacau cgagacggug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cagcgugaac gccgggguca ccacccccgu guccacguac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugccgaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggcguacgug guccagcugc cccucuacgg cgugaucgac acccccugcu      900

ggaagcugca cacgagcccc cugugcacca ccaacaccaa ggaggggucc aacaucugcc      960

ucacgcgcac cgaccggggc ugguacugcg acaacgccgg cagcgucucc uucuucccgc     1020

aggccgagac cugcaaggug ugcagcaacc gcguguucug cgacaccaug aacucccuga     1080

cgcugcccag cgagguaaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgugagcu ccagcgugau caccucccug ggggccaucg     1200

ucagcugcua cggcaagacg aagugcaccg ccagcaacaa gaacaagggg aucaucaaga     1260

ccuucuccaa cggcugcgac uacgugagca acaagggcgu ggacaccgug uccgucggga     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu cuacgugaag ggggagccca     1380

ucaucaacuu cuacgacccg cuggucuucc ccuccgacga guucgacgcg agcaucuccc     1440

aggugaacga gaagaucaac cagagccugg ccuucauccg caaguccgac gagcugcucc     1500

acaacgugaa cgccggcaag agcacgacca acaucaugau caccaccauc aucaucguca     1560

ucaucgugau ccugcugucc cucaucgccg uggggcugcu gcucuacugc aaggcccggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7413
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7413
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcgcaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcaga      360

ugcucaugug cuccaccccc gccaccggca gcggguccgc caucgccagc ggcguggcgg      420

ugugcaaggu ccugcaccug gagggcgagg ugaacaagau caaguccgcc cuccugagca      480

ccaacaaggc cguggucucc cugagcaacg ggguguccgu gcucacguuc aagguccugg      540

accugaagaa cuacaucgac aagcagcucc ugccgauccu gaacaagcag agcugcucca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caaccggcuc cuggagauca      660

cccgcgaguu cuccgugaac gccggcguca ccacgcccgu gagcaccuac augcugacca      720

acagcgagcu ccugucccug aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

ugagcaacaa cgugcagauc guccggcagc aguccuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug guccagcugc cccucuacgg ggugaucgac acgccgugcu      900

ggaagcugca caccagcccc cugugcacca ccaacacgaa ggagggcagc aacaucugcc      960

ucacccgcac cgaccggggg ugguacugcg acaacgcggg cuccgugagc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcguguucug cgacacgaug aacagccuga     1080

cccugcccuc cgaggucaac cucugcaacg uggacaucuu caacccgaag uacgacugca     1140

agaucaugac cagcaagacc gacgugucca gcuccgucau cacgagccug ggcgccaucg     1200

uguccugcua cgggaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cgggugcgac uacgugagca acaagggcgu cgacacggug agcgugggca     1320

acacccugua cuacgucaac aagcaggagg ggaagucccu cuacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc uccaucagcc     1440

aggucaacga gaagaucaac cagucccugg cguucauccg gaaguccgac gagcuccugc     1500

acaacgugaa cgccgggaag uccaccacca acaucaugau caccacgauc aucaucguga     1560

ucaucgucau ccugcucagc cugaucgccg ugggccugcu ccuguacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7414
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7414
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaacaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gagcuccaga      360

ugcucaugug cuccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccaacg gcgucuccgu ccucaccuuc aagguccucg      540

accucaagaa cuacaucgac aagcagcucc uccccauccu caacaagcag uccugcucca      600

ucuccaacau cgagaccguc auggaguucc agcagaagaa caaccgccuc cucgagauca      660

cccgcgaguu cuccgucaac gccggcguca ccacccccgu cuccaccuac augcucacca      720

acuccgagcu ccucucccuc aucaacgaca ugcccaucac caacgaccag aagaagcuca      780

uguccaacaa cguccagauc guccgccagc aguccuacuc caucaugugc aucaucaagg      840

aggagguccu cgccuacguc guccagcucc cccucuacgg cgucaucgac acccccugcu      900

ggaagcucca caccuccccc cucugcacca ccaacaccaa ggagggcucc aacaucugcc      960

ucacccgcac cgaccgcggc ugguacugcg acaacgccgg cuccgucucc uucuuccccc     1020

aggccgagac cugcaagguc ugcuccaacc gcgucuucug cgacaccaug aacucccuca     1080

cccuccccuc cgaggucaac cucugcaacg ucgacaucuu caaccccaag uacgacugca     1140

agaucaugac cuccaagacc gacgucuccu ccuccgucau caccucccuc ggcgccaucg     1200

ucuccugcua cggcaagacc aagugcaccg ccuccaacaa gaacaagggc aucaucaaga     1260

ccuucuccaa cggcugcgac uacgucucca acaagggcgu cgacaccguc uccgucggca     1320

acacccucua cuacgucaac aagcaggagg gcaagucccu cuacgucaag ggcgagccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucuccc     1440

aggucaacga gaagaucaac cagucccucg ccuucauccg caaguccgac gagcuccucc     1500

acaacgucaa cgccggcaag uccaccacca acaucaugau caccaccauc aucaucguca     1560

ucaucgucau ccuccucucc cucaucgccg ucggccuccu ccucuacugc aaggcccgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7415
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7415
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugagugcuuu aagaacugga ugguacacca      240

gcguuauuac aaucgaacug uccaacauua aggagaauaa augcaacggu accgacgcca      300

aggugaaacu aaucaagcag gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga      360

ugcuuaugug uucuacaccc gccaccggcu cggggucagc uauagcaagc ggaguggccg      420

ucugcaaggu gcugcacuug gagggcgaag uuaacaaaau caagagugcu cuccugucca      480

cgaauaaagc cguggucucu cugagcaacg guguguccgu acucacuuuu aagguuuuag      540

accugaagaa uuacauugau aaacagcuuu ugccuauccu gaacaagcaa ucauguagua      600

uuagcaauau cgagaccgug auggaguucc agcagaaaaa caauaggcua cucgaaauaa      660

cacgggaguu uucugucaac gcggggguga cuaccccagu guccacauau augcugacca      720

auucagaacu ucugagcuug auuaacgaca ugccgaucac gaacgaucag aagaaacuca      780

ugaguaauaa cguccaaauu guucgccagc agucuuacuc caucaugugc aucauuaagg      840

aggaagugcu ggcauaugua gugcaguuac cccuguacgg agucauagac acuccuuguu      900

ggaaacucca uacaagccca cuuugcacca cuaauacaaa ggagggcucg aacaucuguc      960

ugacccgaac ggaucguggc ugguacugcg acaaugccgg gucugugucc uucuuucccc     1020

aagcugaaac cuguaagguu ugcucaaaca gaguguucug cgauacaaug aauaguuuga     1080

cucuaccuag cgaggucaac cuguguaaug uggacauuuu uaacccaaaa uaugauugca     1140

agaucaugac cuccaaaaca gacguaucua gcucaguuau aacuagccuc ggagccauug     1200

uguccuguua cgguaagacc aaaugcacag caagcaauaa gaacaagggc aucaucaaaa     1260

ccuucucuaa ugggugugau uaugucucaa acaagggagu ggacacuguc agugugggca     1320

auacgcugua cuauguuaac aaacaggagg guaagagccu uuacgugaaa ggggaaccca     1380

uuaucaacuu uuaugacccu cugguauucc cauccgauga guuugacgcu ucuauuucgc     1440

aggucaauga aaagauaaac caaaguuugg ccuucaucag gaaguccgau gagcuccugc     1500

acaaugugaa cgcgggaaaa ucaacaacca auauuaugau cacuaccauc auuauaguua     1560

ucauugugau cuuacugagu cuaauugccg ucggccuccu gcuuuacugc aaggcacggu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7416
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7416
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugagcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gagcugcaga      360

ugcugaugug cagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg      540

accugaagaa cuacaucgac aagcagcugc ugcccauccu gaacaagcag agcugcagca      600

ucagcaacau cgagaccgug auggaguucc agcagaagaa caacagacug cuggagauca      660

ccagagaguu cagcgugaac gccggcguga ccacccccgu gagcaccuac augcugacca      720

acagcgagcu gcugagccug aucaacgaca ugcccaucac caacgaccag aagaagcuga      780

ugagcaacaa cgugcagauc gugagacagc agagcuacag caucaugugc aucaucaagg      840

aggaggugcu ggccuacgug gugcagcugc cccuguacgg cgugaucgac acccccugcu      900

ggaagcugca caccagcccc cugugcacca ccaacaccaa ggagggcagc aacaucugcc      960

ugaccagaac cgacagaggc ugguacugcg acaacgccgg cagcgugagc uucuuccccc     1020

aggccgagac cugcaaggug ugcagcaaca gaguguucug cgacaccaug aacagccuga     1080

cccugcccag cgaggugaac cugugcaacg uggacaucuu caaccccaag uacgacugca     1140

agaucaugac cagcaagacc gacgugagca gcagcgugau caccagccug ggcgccaucg     1200

ugagcugcua cggcaagacc aagugcaccg ccagcaacaa gaacaagggc aucaucaaga     1260

ccuucagcaa cggcugcgac uacgugagca acaagggcgu ggacaccgug agcgugggca     1320

acacccugua cuacgugaac aagcaggagg gcaagagccu guacgugaag ggcgagccca     1380

ucaucaacuu cuacgacccc cugguguucc ccagcgacga guucgacgcc agcaucagcc     1440

aggugaacga gaagaucaac cagagccugg ccuucaucag aaagagcgac gagcugcugc     1500

acaacgugaa cgccggcaag agcaccacca acaucaugau caccaccauc aucaucguga     1560

ucaucgugau ccugcugagc cugaucgccg ugggccugcu gcuguacugc aaggccagau     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7417
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7417
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc uguccgcccu cagaacagga ugguacaccu      240

cuguuaucac aauugaacug agcaacauca aggagaauaa augcaacggc accgacgcca      300

aggugaaacu uaucaagcag gaacuggaua aguauaaaaa ugcugugacg gagcuccaga      360

ugcugaugug uuccaccccc gccacagggu cuggaagcgc uauugccucc ggcgucgcgg      420

ugugcaaggu ucugcaccuc gagggggaag ugaacaaaau caagagcgcc cugcuuucua      480

ccaauaaagc ugucgugucc cugagcaacg gaguuucugu gcucacauuu aagguccugg      540

accuuaagaa uuacauugau aaacagcugc ucccuauccu gaacaagcaa uccuguagca      600

uuucuaauau cgagaccgug auggaguucc agcagaaaaa caaucggcug cucgaaauua      660

cgcgcgaguu uuccgugaac gccggcguca caaccccggu uagcacauau augcugacca      720

auuccgaacu ucugucucuc aucaacgaca ugcccaucac caacgaucag aagaaacuga      780

ugagcaauaa cgugcaaauu gugagacagc aguccuacag caucaugugc auuaucaagg      840

aggaaguccu ugcuuaugug guucagcugc cucucuacgg cgugauugac acacccuguu      900

ggaaacugca uacgucuccu cugugcacca caaauaccaa ggaggggucc aacaucuguc      960

ucacacggac cgaucgcgga ugguacugcg acaaugccgg cagcgucucu uucuuucccc     1020

aagcggaaac guguaaggug ugcagcaaca gaguuuucug cgauacaaug aacucccuga     1080

cccuuccuuc ugaggugaau cuguguaaug ucgacaucuu uaacccgaaa uaugauugca     1140

agauuaugac cagcaaaaca gacgugucca gcucugucau caccucccuc ggggccauug     1200

ugagcuguua cggaaagaca aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa     1260

ccuucuccaa ugggugugau uauguuagca acaagggagu ggacacaguc uccgugggca     1320

auacccugua cuauguuaac aaacaggagg gcaagucucu uuacgugaaa ggggaaccca     1380

ucaucaacuu uuaugacccu cuggucuucc ccagcgauga guuugacgcc uccauuucuc     1440

aggugaauga aaagaucaac caaagccucg cuuucauucg gaaguccgau gagcugcugc     1500

acaaugugaa cgccggaaaa agcacaacca auaucaugau uacgaccauc auuaucguua     1560

ucauugucau ccuccugucu cuuauugccg ugggccugcu ccuguacugc aaggcucgcu     1620

gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7418
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7418
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaauuacuaa uccucaaagc aaacgcaauu acaaccauac      120

uaaccgcugu caccuuuugu uuugccucag gacaaaacau aacugaagaa uuuuaccaau      180

caacaugcuc cgcaguaucu aaaggauacc ucagcgcguu aagaacagga ugguacacau      240

cgguaauaac caucgaauua uccaacauaa aagaaaauaa augcaaugga acagacgcaa      300

aagucaaauu aauuaaacaa gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa      360

ugcuaaugug uucaacacca gcaacaggau caggaucagc uauagcuuca ggaguugccg      420

uaugcaaagu gcuacacuua gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa      480

cgaacaaagc cguaguaucu cuaucaaaug gcguaucagu acucacauuc aaaguacucg      540

accuaaaaaa cuauauagau aaacaacuau uacccauccu aaauaaacaa agcugcucua      600

uaucaaacau cgaaacagua auggaauuuc aacaaaaaaa caacagacua cuagaaauaa      660

cccgagaguu cucaguuaau gcaggaguaa caacaccagu cucaacauac augcucacaa      720

acucagaacu ccuaucacua auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca      780

ugucuaacaa cguccaaaua guaagacaac aauccuacag cauaaugugu auaauaaaag      840

aagaaguuuu agcauacguc guacaacuac ccuuauaugg cguaauagau acaccaugcu      900

ggaaacucca uaccucaccu cuauguacaa caaauaccaa agaagguucu aauauaugcc      960

uaacacgaac ugaccgagga ugguacugug acaacgcagg aucagucucu uucuuuccac     1020

aagcagaaac cugcaaagua ugcaguaacc gcguauuuug cgacacaaug aacucccuaa     1080

ccuuaccauc agaaguaaac uuauguaacg uagacauauu caauccaaaa uaugacugca     1140

aaauaaugac aucaaaaaca gacguaagcu caucaguaau aacuucacua ggcgcaauug     1200

uaucaugcua uggaaaaacc aaauguaccg cauccaacaa aaauaaagga auaauaaaaa     1260

ccuucucuaa cggaugcgac uacguaucaa acaaaggugu agauacaguu ucuguaggaa     1320

acacacucua cuauguaaau aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa     1380

uaauaaacuu cuaugaccca cuuguauuuc caucugauga auuugaugca agcauaucac     1440

aaguaaacga aaaaauaaac caaucucuag ccuuuauacg aaaaagcgac gaauuacuac     1500

auaacgucaa cgcuggaaaa ucaacaacaa acauaaugau aacaacaaua auaauaguaa     1560

uaauagucau ccuauuauca cuaaucgccg uaggacuacu ccuauacugc aaagcuagau     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7419
<211>  2117
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7419
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccaua accacuaucc      120

ucacagcagu cacuuucugc uucgccucag gacaaaacau aaccgaagag uucuaccaau      180

ccacaugcuc cgccgucucc aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau      240

ccgucaucac caucgaacua agcaacauaa aagaaaacaa augcaacggc accgacgcca      300

aaguuaaacu caucaagcaa gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa      360

ugcucaugug cuccacaccc gccacagguu cuggcucagc aaucgcaagc ggcgucgccg      420

uaugcaaagu ccuucaccuc gaaggcgaag ucaacaaaau caaauccgcc cuccucucca      480

ccaauaaagc ugucgucuca cucuccaacg gcgucagcgu ccucacauuc aaaguccucg      540

accucaaaaa cuacauagac aagcaacucc ucccgauacu caacaaacaa agcugcucua      600

ucuccaacau cgaaaccguc auggaguucc aacagaaaaa caaucgucuc cucgaaauca      660

cccgcgaguu cucaguaaac gccgggguca ccacaccagu cuccaccuac augcucacca      720

acuccgaacu ccuuagccuc auaaacgaca ugcccauaac caacgaccaa aagaaacuca      780

ugagcaacaa cguacaaaua guccgacaac aauccuauuc caucaugugu aucaucaaag      840

aagaaguccu cgcauacgua guccaacucc cccuauacgg cguaaucgac accccauguu      900

ggaaacucca caccucacca cucuguacca ccaacaccaa agaaggcuca aacaucugcc      960

ucacccgcac agaccgcggc ugguacugcg acaacgcggg cuccgucagc uucuuucccc     1020

aagcggaaac cugcaaaguc ugcagcaaca gagucuucug cgacacuaug aacucccuca     1080

cccuccccuc agaagucaac cucugcaacg ucgacaucuu caacccgaaa uacgacugca     1140

aaaucaugac cagcaaaacu gacgucuccu cguccgucau caccucacuc ggcgcaaucg     1200

ugagcugcua cggcaaaacc aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa     1260

cauucagcaa cggcugcgac uacgucucga acaaaggagu cgacaccgua ucagugggca     1320

acacccuaua cuacguaaac aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca     1380

ucaucaacuu cuacgacccc cucgucuucc ccuccgacga guucgacgcc uccaucucuc     1440

aagucaacga gaaaaucaac caaucccuug ccuucauacg uaaaagcgac gaacuccuuc     1500

acaacguaaa cgccgggaaa uccaccacua acauaaugau caccaccauc aucaucguua     1560

ucauagucau ccuccucucu cucauagcag ucggccuacu ccuguacugc aaagcgcgcu     1620

aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu aauuaagagu     1680

gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac accgcaaccu     1740

uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc uuagauguuc     1800

caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu     1860

cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau     1920

ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga     1980

gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     2100

ucagagccac cagaauu                                                    2117


<210>  7420
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7420
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7421
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7421
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7422
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7422
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7423
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7423
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7424
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7424
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7425
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7425
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cugaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7426
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7426
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccucaaa gcaaacgcaa uuacaaccau acuaaccgcu      120

gucaccuuuu guuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacaugc      180

uccgcaguau cuaaaggaua ccucagcgcg uuaagaacag gaugguacac aucgguaaua      240

accaucgaau uauccaacau aaaagaaaau aaaugcaaug gaacagacgc aaaagucaaa      300

uuaauuaaac aagaacuaga caaauauaaa aacgcaguaa ccgaauuaca aaugcuaaug      360

uguucaacac cagcaacagg aucaggauca gcuauagcuu caggaguugc cguaugcaaa      420

gugcuacacu uagaaggaga agugaauaaa auaaaaucag cucuauuauc aacgaacaaa      480

gccguaguau cucuaucaaa uggcguauca guacucacau ucaaaguacu cgaccuaaaa      540

aacuauauag auaaacaacu auuacccauc cuaaauaaac aaagcugcuc uauaucaaac      600

aucgaaacag uaauggaauu ucaacaaaaa aacaacagac uacuagaaau aacccgagag      660

uucucaguua augcaggagu aacaacacca gucucaacau acaugcucac aaacucagaa      720

cuccuaucac uaauaaauga caugccaaua acaaacgacc aaaaaaaacu caugucuaac      780

aacguccaaa uaguaagaca acaauccuac agcauaaugu guauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu acccuuauau ggcguaauag auacaccaug cuggaaacuc      900

cauaccucac cucuauguac aacaaauacc aaagaagguu cuaauauaug ccuaacacga      960

acugaccgag gaugguacug ugacaacgca ggaucagucu cuuucuuucc acaagcagaa     1020

accugcaaag uaugcaguaa ccgcguauuu ugcgacacaa ugaacucccu aaccuuacca     1080

ucagaaguaa acuuauguaa cguagacaua uucaauccaa aauaugacug caaaauaaug     1140

acaucaaaaa cagacguaag cucaucagua auaacuucac uaggcgcaau uguaucaugc     1200

uauggaaaaa ccaaauguac cgcauccaac aaaaauaaag gaauaauaaa aaccuucucu     1260

aacggaugcg acuacguauc aaacaaaggu guagauacag uuucuguagg aaacacacuc     1320

uacuauguaa auaaacaaga aggaaaauca cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cacuuguauu uccaucugau gaauuugaug caagcauauc acaaguaaac     1440

gaaaaaauaa accaaucucu agccuuuaua cgaaaaagcg acgaauuacu acauaacguc     1500

aacgcuggaa aaucaacaac aaacauaaug auaacaacaa uaauaauagu aauaauaguc     1560

auccuauuau cacuaaucgc cguaggacua cuccuauacu gcaaagcuag auaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7427
<211>  1893
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7427
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacuau ccucacagca      120

gucacuuucu gcuucgccuc aggacaaaac auaaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaaaggcua ccucucagcg cuccgcaccg gcugguacac auccgucauc      240

accaucgaac uaagcaacau aaaagaaaac aaaugcaacg gcaccgacgc caaaguuaaa      300

cucaucaagc aagaacucga caaauacaaa aacgcaguca cagaacuuca aaugcucaug      360

ugcuccacac ccgccacagg uucuggcuca gcaaucgcaa gcggcgucgc cguaugcaaa      420

guccuucacc ucgaaggcga agucaacaaa aucaaauccg cccuccucuc caccaauaaa      480

gcugucgucu cacucuccaa cggcgucagc guccucacau ucaaaguccu cgaccucaaa      540

aacuacauag acaagcaacu ccucccgaua cucaacaaac aaagcugcuc uaucuccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaucguc uccucgaaau cacccgcgag      660

uucucaguaa acgccggggu caccacacca gucuccaccu acaugcucac caacuccgaa      720

cuccuuagcc ucauaaacga caugcccaua accaacgacc aaaagaaacu caugagcaac      780

aacguacaaa uaguccgaca acaauccuau uccaucaugu guaucaucaa agaagaaguc      840

cucgcauacg uaguccaacu cccccuauac ggcguaaucg acaccccaug uuggaaacuc      900

cacaccucac cacucuguac caccaacacc aaagaaggcu caaacaucug ccucacccgc      960

acagaccgcg gcugguacug cgacaacgcg ggcuccguca gcuucuuucc ccaagcggaa     1020

accugcaaag ucugcagcaa cagagucuuc ugcgacacua ugaacucccu cacccucccc     1080

ucagaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaaucaug     1140

accagcaaaa cugacgucuc cucguccguc aucaccucac ucggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aacauucagc     1260

aacggcugcg acuacgucuc gaacaaagga gucgacaccg uaucaguggg caacacccua     1320

uacuacguaa acaagcaaga aggcaaauca cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ucaagucaac     1440

gagaaaauca accaaucccu ugccuucaua cguaaaagcg acgaacuccu ucacaacgua     1500

aacgccggga aauccaccac uaacauaaug aucaccacca ucaucaucgu uaucauaguc     1560

auccuccucu cucucauagc agucggccua cuccuguacu gcaaagcgcg cuaaggacua     1620

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1680

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1740

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1860

cccccaaagg cucuuuucag agccaccaga auu                                  1893


<210>  7428
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7428
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcugaug      360

ugcuccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccaa cggcgucagc gugcugaccu ucaaggugcu ggaccucaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcuc caucagcaac      600

aucgagacgg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucagcguga acgccggggu caccaccccc guguccacgu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugccgauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggcguacg ugguccagcu gccccucuac ggcgugaucg acacccccug cuggaagcug      900

cacacgagcc cccugugcac caccaacacc aaggaggggu ccaacaucug ccucacgcgc      960

accgaccggg gcugguacug cgacaacgcc ggcagcgucu ccuucuuccc gcaggccgag     1020

accugcaagg ugugcagcaa ccgcguguuc ugcgacacca ugaacucccu gacgcugccc     1080

agcgagguaa accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgugag cuccagcgug aucaccuccc ugggggccau cgucagcugc     1200

uacggcaaga cgaagugcac cgccagcaac aagaacaagg ggaucaucaa gaccuucucc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg uguccgucgg gaacacccug     1320

uacuacguga acaagcagga gggcaagagc cucuacguga agggggagcc caucaucaac     1380

uucuacgacc cgcuggucuu ccccuccgac gaguucgacg cgagcaucuc ccaggugaac     1440

gagaagauca accagagccu ggccuucauc cgcaaguccg acgagcugcu ccacaacgug     1500

aacgccggca agagcacgac caacaucaug aucaccacca ucaucaucgu caucaucgug     1560

auccugcugu cccucaucgc cguggggcug cugcucuacu gcaaggcccg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7429
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7429
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucagcgcc cugcgcaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggagcugca gaugcucaug      360

ugcuccaccc ccgccaccgg cagcgggucc gccaucgcca gcggcguggc ggugugcaag      420

guccugcacc uggagggcga ggugaacaag aucaaguccg cccuccugag caccaacaag      480

gccguggucu cccugagcaa cggggugucc gugcucacgu ucaagguccu ggaccugaag      540

aacuacaucg acaagcagcu ccugccgauc cugaacaagc agagcugcuc caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaaccggc uccuggagau cacccgcgag      660

uucuccguga acgccggcgu caccacgccc gugagcaccu acaugcugac caacagcgag      720

cuccuguccc ugaucaacga caugcccauc accaacgacc agaagaagcu caugagcaac      780

aacgugcaga ucguccggca gcaguccuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg ugguccagcu gccccucuac ggggugaucg acacgccgug cuggaagcug      900

cacaccagcc cccugugcac caccaacacg aaggagggca gcaacaucug ccucacccgc      960

accgaccggg ggugguacug cgacaacgcg ggcuccguga gcuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcguguuc ugcgacacga ugaacagccu gacccugccc     1080

uccgagguca accucugcaa cguggacauc uucaacccga aguacgacug caagaucaug     1140

accagcaaga ccgacguguc cagcuccguc aucacgagcc ugggcgccau cguguccugc     1200

uacgggaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacgggugcg acuacgugag caacaagggc gucgacacgg ugagcguggg caacacccug     1320

uacuacguca acaagcagga ggggaagucc cucuacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccuccaucag ccaggucaac     1440

gagaagauca accagucccu ggcguucauc cggaaguccg acgagcuccu gcacaacgug     1500

aacgccggga aguccaccac caacaucaug aucaccacga ucaucaucgu gaucaucguc     1560

auccugcuca gccugaucgc cgugggccug cuccuguacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7430
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7430
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucuccgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagaac aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgagcucca gaugcucaug      360

ugcuccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccaa cggcgucucc guccucaccu ucaagguccu cgaccucaag      540

aacuacaucg acaagcagcu ccuccccauc cucaacaagc aguccugcuc caucuccaac      600

aucgagaccg ucauggaguu ccagcagaag aacaaccgcc uccucgagau cacccgcgag      660

uucuccguca acgccggcgu caccaccccc gucuccaccu acaugcucac caacuccgag      720

cuccucuccc ucaucaacga caugcccauc accaacgacc agaagaagcu cauguccaac      780

aacguccaga ucguccgcca gcaguccuac uccaucaugu gcaucaucaa ggaggagguc      840

cucgccuacg ucguccagcu cccccucuac ggcgucaucg acacccccug cuggaagcuc      900

cacaccuccc cccucugcac caccaacacc aaggagggcu ccaacaucug ccucacccgc      960

accgaccgcg gcugguacug cgacaacgcc ggcuccgucu ccuucuuccc ccaggccgag     1020

accugcaagg ucugcuccaa ccgcgucuuc ugcgacacca ugaacucccu cacccucccc     1080

uccgagguca accucugcaa cgucgacauc uucaacccca aguacgacug caagaucaug     1140

accuccaaga ccgacgucuc cuccuccguc aucaccuccc ucggcgccau cgucuccugc     1200

uacggcaaga ccaagugcac cgccuccaac aagaacaagg gcaucaucaa gaccuucucc     1260

aacggcugcg acuacgucuc caacaagggc gucgacaccg ucuccgucgg caacacccuc     1320

uacuacguca acaagcagga gggcaagucc cucuacguca agggcgagcc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ccaggucaac     1440

gagaagauca accagucccu cgccuucauc cgcaaguccg acgagcuccu ccacaacguc     1500

aacgccggca aguccaccac caacaucaug aucaccacca ucaucaucgu caucaucguc     1560

auccuccucu cccucaucgc cgucggccuc cuccucuacu gcaaggcccg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7431
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7431
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugagugcu uuaagaacug gaugguacac cagcguuauu      240

acaaucgaac uguccaacau uaaggagaau aaaugcaacg guaccgacgc caaggugaaa      300

cuaaucaagc aggaacucga uaaguauaaa aaugcaguaa cugagcugca gaugcuuaug      360

uguucuacac ccgccaccgg cucgggguca gcuauagcaa gcggaguggc cgucugcaag      420

gugcugcacu uggagggcga aguuaacaaa aucaagagug cucuccuguc cacgaauaaa      480

gccguggucu cucugagcaa cggugugucc guacucacuu uuaagguuuu agaccugaag      540

aauuacauug auaaacagcu uuugccuauc cugaacaagc aaucauguag uauuagcaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaauaggc uacucgaaau aacacgggag      660

uuuucuguca acgcgggggu gacuacccca guguccacau auaugcugac caauucagaa      720

cuucugagcu ugauuaacga caugccgauc acgaacgauc agaagaaacu caugaguaau      780

aacguccaaa uuguucgcca gcagucuuac uccaucaugu gcaucauuaa ggaggaagug      840

cuggcauaug uagugcaguu accccuguac ggagucauag acacuccuug uuggaaacuc      900

cauacaagcc cacuuugcac cacuaauaca aaggagggcu cgaacaucug ucugacccga      960

acggaucgug gcugguacug cgacaaugcc gggucugugu ccuucuuucc ccaagcugaa     1020

accuguaagg uuugcucaaa cagaguguuc ugcgauacaa ugaauaguuu gacucuaccu     1080

agcgagguca accuguguaa uguggacauu uuuaacccaa aauaugauug caagaucaug     1140

accuccaaaa cagacguauc uagcucaguu auaacuagcc ucggagccau uguguccugu     1200

uacgguaaga ccaaaugcac agcaagcaau aagaacaagg gcaucaucaa aaccuucucu     1260

aaugggugug auuaugucuc aaacaaggga guggacacug ucaguguggg caauacgcug     1320

uacuauguua acaaacagga ggguaagagc cuuuacguga aaggggaacc cauuaucaac     1380

uuuuaugacc cucugguauu cccauccgau gaguuugacg cuucuauuuc gcaggucaau     1440

gaaaagauaa accaaaguuu ggccuucauc aggaaguccg augagcuccu gcacaaugug     1500

aacgcgggaa aaucaacaac caauauuaug aucacuacca ucauuauagu uaucauugug     1560

aucuuacuga gucuaauugc cgucggccuc cugcuuuacu gcaaggcacg gugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7432
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7432
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugagcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagaac aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgagcugca gaugcugaug      360

ugcagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcaa cggcgugagc gugcugaccu ucaaggugcu ggaccugaag      540

aacuacaucg acaagcagcu gcugcccauc cugaacaagc agagcugcag caucagcaac      600

aucgagaccg ugauggaguu ccagcagaag aacaacagac ugcuggagau caccagagag      660

uucagcguga acgccggcgu gaccaccccc gugagcaccu acaugcugac caacagcgag      720

cugcugagcc ugaucaacga caugcccauc accaacgacc agaagaagcu gaugagcaac      780

aacgugcaga ucgugagaca gcagagcuac agcaucaugu gcaucaucaa ggaggaggug      840

cuggccuacg uggugcagcu gccccuguac ggcgugaucg acacccccug cuggaagcug      900

cacaccagcc cccugugcac caccaacacc aaggagggca gcaacaucug ccugaccaga      960

accgacagag gcugguacug cgacaacgcc ggcagcguga gcuucuuccc ccaggccgag     1020

accugcaagg ugugcagcaa cagaguguuc ugcgacacca ugaacagccu gacccugccc     1080

agcgagguga accugugcaa cguggacauc uucaacccca aguacgacug caagaucaug     1140

accagcaaga ccgacgugag cagcagcgug aucaccagcc ugggcgccau cgugagcugc     1200

uacggcaaga ccaagugcac cgccagcaac aagaacaagg gcaucaucaa gaccuucagc     1260

aacggcugcg acuacgugag caacaagggc guggacaccg ugagcguggg caacacccug     1320

uacuacguga acaagcagga gggcaagagc cuguacguga agggcgagcc caucaucaac     1380

uucuacgacc cccugguguu ccccagcgac gaguucgacg ccagcaucag ccaggugaac     1440

gagaagauca accagagccu ggccuucauc agaaagagcg acgagcugcu gcacaacgug     1500

aacgccggca agagcaccac caacaucaug aucaccacca ucaucaucgu gaucaucgug     1560

auccugcuga gccugaucgc cgugggccug cugcuguacu gcaaggccag augaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7433
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7433
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucuguccgcc cucagaacag gaugguacac cucuguuauc      240

acaauugaac ugagcaacau caaggagaau aaaugcaacg gcaccgacgc caaggugaaa      300

cuuaucaagc aggaacugga uaaguauaaa aaugcuguga cggagcucca gaugcugaug      360

uguuccaccc ccgccacagg gucuggaagc gcuauugccu ccggcgucgc ggugugcaag      420

guucugcacc ucgaggggga agugaacaaa aucaagagcg cccugcuuuc uaccaauaaa      480

gcugucgugu cccugagcaa cggaguuucu gugcucacau uuaagguccu ggaccuuaag      540

aauuacauug auaaacagcu gcucccuauc cugaacaagc aauccuguag cauuucuaau      600

aucgagaccg ugauggaguu ccagcagaaa aacaaucggc ugcucgaaau uacgcgcgag      660

uuuuccguga acgccggcgu cacaaccccg guuagcacau auaugcugac caauuccgaa      720

cuucugucuc ucaucaacga caugcccauc accaacgauc agaagaaacu gaugagcaau      780

aacgugcaaa uugugagaca gcaguccuac agcaucaugu gcauuaucaa ggaggaaguc      840

cuugcuuaug ugguucagcu gccucucuac ggcgugauug acacacccug uuggaaacug      900

cauacgucuc cucugugcac cacaaauacc aaggaggggu ccaacaucug ucucacacgg      960

accgaucgcg gaugguacug cgacaaugcc ggcagcgucu cuuucuuucc ccaagcggaa     1020

acguguaagg ugugcagcaa cagaguuuuc ugcgauacaa ugaacucccu gacccuuccu     1080

ucugagguga aucuguguaa ugucgacauc uuuaacccga aauaugauug caagauuaug     1140

accagcaaaa cagacguguc cagcucuguc aucaccuccc ucggggccau ugugagcugu     1200

uacggaaaga caaaaugcac ggcuucuaau aagaacaagg gcaucauuaa aaccuucucc     1260

aaugggugug auuauguuag caacaaggga guggacacag ucuccguggg caauacccug     1320

uacuauguua acaaacagga gggcaagucu cuuuacguga aaggggaacc caucaucaac     1380

uuuuaugacc cucuggucuu ccccagcgau gaguuugacg ccuccauuuc ucaggugaau     1440

gaaaagauca accaaagccu cgcuuucauu cggaaguccg augagcugcu gcacaaugug     1500

aacgccggaa aaagcacaac caauaucaug auuacgacca ucauuaucgu uaucauuguc     1560

auccuccugu cucuuauugc cgugggccug cuccuguacu gcaaggcucg cugaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7434
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7434
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaauuacu aauccucaaa gcaaacgcaa uuacaaccau acuaaccgcu      120

gucaccuuuu guuuugccuc aggacaaaac auaacugaag aauuuuacca aucaacaugc      180

uccgcaguau cuaaaggaua ccucagcgcg uuaagaacag gaugguacac aucgguaaua      240

accaucgaau uauccaacau aaaagaaaau aaaugcaaug gaacagacgc aaaagucaaa      300

uuaauuaaac aagaacuaga caaauauaaa aacgcaguaa ccgaauuaca aaugcuaaug      360

uguucaacac cagcaacagg aucaggauca gcuauagcuu caggaguugc cguaugcaaa      420

gugcuacacu uagaaggaga agugaauaaa auaaaaucag cucuauuauc aacgaacaaa      480

gccguaguau cucuaucaaa uggcguauca guacucacau ucaaaguacu cgaccuaaaa      540

aacuauauag auaaacaacu auuacccauc cuaaauaaac aaagcugcuc uauaucaaac      600

aucgaaacag uaauggaauu ucaacaaaaa aacaacagac uacuagaaau aacccgagag      660

uucucaguua augcaggagu aacaacacca gucucaacau acaugcucac aaacucagaa      720

cuccuaucac uaauaaauga caugccaaua acaaacgacc aaaaaaaacu caugucuaac      780

aacguccaaa uaguaagaca acaauccuac agcauaaugu guauaauaaa agaagaaguu      840

uuagcauacg ucguacaacu acccuuauau ggcguaauag auacaccaug cuggaaacuc      900

cauaccucac cucuauguac aacaaauacc aaagaagguu cuaauauaug ccuaacacga      960

acugaccgag gaugguacug ugacaacgca ggaucagucu cuuucuuucc acaagcagaa     1020

accugcaaag uaugcaguaa ccgcguauuu ugcgacacaa ugaacucccu aaccuuacca     1080

ucagaaguaa acuuauguaa cguagacaua uucaauccaa aauaugacug caaaauaaug     1140

acaucaaaaa cagacguaag cucaucagua auaacuucac uaggcgcaau uguaucaugc     1200

uauggaaaaa ccaaauguac cgcauccaac aaaaauaaag gaauaauaaa aaccuucucu     1260

aacggaugcg acuacguauc aaacaaaggu guagauacag uuucuguagg aaacacacuc     1320

uacuauguaa auaaacaaga aggaaaauca cuauacguaa aaggagaacc aauaauaaac     1380

uucuaugacc cacuuguauu uccaucugau gaauuugaug caagcauauc acaaguaaac     1440

gaaaaaauaa accaaucucu agccuuuaua cgaaaaagcg acgaauuacu acauaacguc     1500

aacgcuggaa aaucaacaac aaacauaaug auaacaacaa uaauaauagu aauaauaguc     1560

auccuauuau cacuaaucgc cguaggacua cuccuauacu gcaaagcuag auaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7435
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7435
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca uaaccacuau ccucacagca      120

gucacuuucu gcuucgccuc aggacaaaac auaaccgaag aguucuacca auccacaugc      180

uccgccgucu ccaaaggcua ccucucagcg cuccgcaccg gcugguacac auccgucauc      240

accaucgaac uaagcaacau aaaagaaaac aaaugcaacg gcaccgacgc caaaguuaaa      300

cucaucaagc aagaacucga caaauacaaa aacgcaguca cagaacuuca aaugcucaug      360

ugcuccacac ccgccacagg uucuggcuca gcaaucgcaa gcggcgucgc cguaugcaaa      420

guccuucacc ucgaaggcga agucaacaaa aucaaauccg cccuccucuc caccaauaaa      480

gcugucgucu cacucuccaa cggcgucagc guccucacau ucaaaguccu cgaccucaaa      540

aacuacauag acaagcaacu ccucccgaua cucaacaaac aaagcugcuc uaucuccaac      600

aucgaaaccg ucauggaguu ccaacagaaa aacaaucguc uccucgaaau cacccgcgag      660

uucucaguaa acgccggggu caccacacca gucuccaccu acaugcucac caacuccgaa      720

cuccuuagcc ucauaaacga caugcccaua accaacgacc aaaagaaacu caugagcaac      780

aacguacaaa uaguccgaca acaauccuau uccaucaugu guaucaucaa agaagaaguc      840

cucgcauacg uaguccaacu cccccuauac ggcguaaucg acaccccaug uuggaaacuc      900

cacaccucac cacucuguac caccaacacc aaagaaggcu caaacaucug ccucacccgc      960

acagaccgcg gcugguacug cgacaacgcg ggcuccguca gcuucuuucc ccaagcggaa     1020

accugcaaag ucugcagcaa cagagucuuc ugcgacacua ugaacucccu cacccucccc     1080

ucagaaguca accucugcaa cgucgacauc uucaacccga aauacgacug caaaaucaug     1140

accagcaaaa cugacgucuc cucguccguc aucaccucac ucggcgcaau cgugagcugc     1200

uacggcaaaa ccaaaugcac cgccuccaac aaaaacaaag gcaucauaaa aacauucagc     1260

aacggcugcg acuacgucuc gaacaaagga gucgacaccg uaucaguggg caacacccua     1320

uacuacguaa acaagcaaga aggcaaauca cucuacguaa aaggcgaacc caucaucaac     1380

uucuacgacc cccucgucuu ccccuccgac gaguucgacg ccuccaucuc ucaagucaac     1440

gagaaaauca accaaucccu ugccuucaua cguaaaagcg acgaacuccu ucacaacgua     1500

aacgccggga aauccaccac uaacauaaug aucaccacca ucaucaucgu uaucauaguc     1560

auccuccucu cucucauagc agucggccua cuccuguacu gcaaagcgcg cuaaggacua     1620

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1680

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1740

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1860

caaaggcucu uuucagagcc accagaauu                                       1889


<210>  7436
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7436
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7437
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7437
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7438
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7438
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7439
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7439
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacggug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7440
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7440
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7441
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7441
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcug aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7442
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7442
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccucaaagca      120

aacgcaauua caaccauacu aaccgcuguc accuuuuguu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacaugcucc gcaguaucua aaggauaccu cagcgcguua      240

agaacaggau gguacacauc gguaauaacc aucgaauuau ccaacauaaa agaaaauaaa      300

ugcaauggaa cagacgcaaa agucaaauua auuaaacaag aacuagacaa auauaaaaac      360

gcaguaaccg aauuacaaau gcuaaugugu ucaacaccag caacaggauc aggaucagcu      420

auagcuucag gaguugccgu augcaaagug cuacacuuag aaggagaagu gaauaaaaua      480

aaaucagcuc uauuaucaac gaacaaagcc guaguaucuc uaucaaaugg cguaucagua      540

cucacauuca aaguacucga ccuaaaaaac uauauagaua aacaacuauu acccauccua      600

aauaaacaaa gcugcucuau aucaaacauc gaaacaguaa uggaauuuca acaaaaaaac      660

aacagacuac uagaaauaac ccgagaguuc ucaguuaaug caggaguaac aacaccaguc      720

ucaacauaca ugcucacaaa cucagaacuc cuaucacuaa uaaaugacau gccaauaaca      780

aacgaccaaa aaaaacucau gucuaacaac guccaaauag uaagacaaca auccuacagc      840

auaaugugua uaauaaaaga agaaguuuua gcauacgucg uacaacuacc cuuauauggc      900

guaauagaua caccaugcug gaaacuccau accucaccuc uauguacaac aaauaccaaa      960

gaagguucua auauaugccu aacacgaacu gaccgaggau gguacuguga caacgcagga     1020

ucagucucuu ucuuuccaca agcagaaacc ugcaaaguau gcaguaaccg cguauuuugc     1080

gacacaauga acucccuaac cuuaccauca gaaguaaacu uauguaacgu agacauauuc     1140

aauccaaaau augacugcaa aauaaugaca ucaaaaacag acguaagcuc aucaguaaua     1200

acuucacuag gcgcaauugu aucaugcuau ggaaaaacca aauguaccgc auccaacaaa     1260

aauaaaggaa uaauaaaaac cuucucuaac ggaugcgacu acguaucaaa caaaggugua     1320

gauacaguuu cuguaggaaa cacacucuac uauguaaaua aacaagaagg aaaaucacua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccac uuguauuucc aucugaugaa     1440

uuugaugcaa gcauaucaca aguaaacgaa aaaauaaacc aaucucuagc cuuuauacga     1500

aaaagcgacg aauuacuaca uaacgucaac gcuggaaaau caacaacaaa cauaaugaua     1560

acaacaauaa uaauaguaau aauagucauc cuauuaucac uaaucgccgu aggacuacuc     1620

cuauacugca aagcuagaua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7443
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7443
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacuauccu cacagcaguc acuuucugcu ucgccucagg acaaaacaua      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca aaggcuaccu cucagcgcuc      240

cgcaccggcu gguacacauc cgucaucacc aucgaacuaa gcaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa aguuaaacuc aucaagcaag aacucgacaa auacaaaaac      360

gcagucacag aacuucaaau gcucaugugc uccacacccg ccacagguuc uggcucagca      420

aucgcaagcg gcgucgccgu augcaaaguc cuucaccucg aaggcgaagu caacaaaauc      480

aaauccgccc uccucuccac caauaaagcu gucgucucac ucuccaacgg cgucagcguc      540

cucacauuca aaguccucga ccucaaaaac uacauagaca agcaacuccu cccgauacuc      600

aacaaacaaa gcugcucuau cuccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaucgucucc ucgaaaucac ccgcgaguuc ucaguaaacg ccggggucac cacaccaguc      720

uccaccuaca ugcucaccaa cuccgaacuc cuuagccuca uaaacgacau gcccauaacc      780

aacgaccaaa agaaacucau gagcaacaac guacaaauag uccgacaaca auccuauucc      840

aucaugugua ucaucaaaga agaaguccuc gcauacguag uccaacuccc ccuauacggc      900

guaaucgaca ccccauguug gaaacuccac accucaccac ucuguaccac caacaccaaa      960

gaaggcucaa acaucugccu cacccgcaca gaccgcggcu gguacugcga caacgcgggc     1020

uccgucagcu ucuuucccca agcggaaacc ugcaaagucu gcagcaacag agucuucugc     1080

gacacuauga acucccucac ccuccccuca gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aaucaugacc agcaaaacug acgucuccuc guccgucauc     1200

accucacucg gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac auucagcaac ggcugcgacu acgucucgaa caaaggaguc     1320

gacaccguau cagugggcaa cacccuauac uacguaaaca agcaagaagg caaaucacuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucucuca agucaacgag aaaaucaacc aaucccuugc cuucauacgu     1500

aaaagcgacg aacuccuuca caacguaaac gccgggaaau ccaccacuaa cauaaugauc     1560

accaccauca ucaucguuau cauagucauc cuccucucuc ucauagcagu cggccuacuc     1620

cuguacugca aagcgcgcua aggacuagua auaaggaaac uguaugaaug ucugugggca     1680

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1740

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  7444
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7444
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcugaugugc uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccaacgg cgucagcgug      540

cugaccuuca aggugcugga ccucaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcuccau cagcaacauc gagacgguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc agcgugaacg ccggggucac cacccccgug      720

uccacguaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gccgaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gcguacgugg uccagcugcc ccucuacggc      900

gugaucgaca cccccugcug gaagcugcac acgagccccc ugugcaccac caacaccaag      960

gaggggucca acaucugccu cacgcgcacc gaccggggcu gguacugcga caacgccggc     1020

agcgucuccu ucuucccgca ggccgagacc ugcaaggugu gcagcaaccg cguguucugc     1080

gacaccauga acucccugac gcugcccagc gagguaaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgugagcuc cagcgugauc     1200

accucccugg gggccaucgu cagcugcuac ggcaagacga agugcaccgc cagcaacaag     1260

aacaagggga ucaucaagac cuucuccaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccgugu ccgucgggaa cacccuguac uacgugaaca agcaggaggg caagagccuc     1380

uacgugaagg gggagcccau caucaacuuc uacgacccgc uggucuuccc cuccgacgag     1440

uucgacgcga gcaucuccca ggugaacgag aagaucaacc agagccuggc cuucauccgc     1500

aaguccgacg agcugcucca caacgugaac gccggcaaga gcacgaccaa caucaugauc     1560

accaccauca ucaucgucau caucgugauc cugcuguccc ucaucgccgu ggggcugcug     1620

cucuacugca aggcccggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7445
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7445
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cagcgcccug      240

cgcaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg agcugcagau gcucaugugc uccacccccg ccaccggcag cggguccgcc      420

aucgccagcg gcguggcggu gugcaagguc cugcaccugg agggcgaggu gaacaagauc      480

aaguccgccc uccugagcac caacaaggcc guggucuccc ugagcaacgg gguguccgug      540

cucacguuca agguccugga ccugaagaac uacaucgaca agcagcuccu gccgauccug      600

aacaagcaga gcugcuccau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aaccggcucc uggagaucac ccgcgaguuc uccgugaacg ccggcgucac cacgcccgug      720

agcaccuaca ugcugaccaa cagcgagcuc cugucccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau gagcaacaac gugcagaucg uccggcagca guccuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg uccagcugcc ccucuacggg      900

gugaucgaca cgccgugcug gaagcugcac accagccccc ugugcaccac caacacgaag      960

gagggcagca acaucugccu cacccgcacc gaccgggggu gguacugcga caacgcgggc     1020

uccgugagcu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cguguucugc     1080

gacacgauga acagccugac ccugcccucc gaggucaacc ucugcaacgu ggacaucuuc     1140

aacccgaagu acgacugcaa gaucaugacc agcaagaccg acguguccag cuccgucauc     1200

acgagccugg gcgccaucgu guccugcuac gggaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucuccaac gggugcgacu acgugagcaa caagggcguc     1320

gacacgguga gcgugggcaa cacccuguac uacgucaaca agcaggaggg gaagucccuc     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgccu ccaucagcca ggucaacgag aagaucaacc agucccuggc guucauccgg     1500

aaguccgacg agcuccugca caacgugaac gccgggaagu ccaccaccaa caucaugauc     1560

accacgauca ucaucgugau caucgucauc cugcucagcc ugaucgccgu gggccugcuc     1620

cuguacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7446
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7446
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cuccgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg agcuccagau gcucaugugc uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccaacgg cgucuccguc      540

cucaccuuca agguccucga ccucaagaac uacaucgaca agcagcuccu ccccauccuc      600

aacaagcagu ccugcuccau cuccaacauc gagaccguca uggaguucca gcagaagaac      660

aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg ccggcgucac cacccccguc      720

uccaccuaca ugcucaccaa cuccgagcuc cucucccuca ucaacgacau gcccaucacc      780

aacgaccaga agaagcucau guccaacaac guccagaucg uccgccagca guccuacucc      840

aucaugugca ucaucaagga ggagguccuc gccuacgucg uccagcuccc ccucuacggc      900

gucaucgaca cccccugcug gaagcuccac accucccccc ucugcaccac caacaccaag      960

gagggcucca acaucugccu cacccgcacc gaccgcggcu gguacugcga caacgccggc     1020

uccgucuccu ucuuccccca ggccgagacc ugcaaggucu gcuccaaccg cgucuucugc     1080

gacaccauga acucccucac ccuccccucc gaggucaacc ucugcaacgu cgacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc uccaagaccg acgucuccuc cuccgucauc     1200

accucccucg gcgccaucgu cuccugcuac ggcaagacca agugcaccgc cuccaacaag     1260

aacaagggca ucaucaagac cuucuccaac ggcugcgacu acgucuccaa caagggcguc     1320

gacaccgucu ccgucggcaa cacccucuac uacgucaaca agcaggaggg caagucccuc     1380

uacgucaagg gcgagcccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucuccca ggucaacgag aagaucaacc agucccucgc cuucauccgc     1500

aaguccgacg agcuccucca caacgucaac gccggcaagu ccaccaccaa caucaugauc     1560

accaccauca ucaucgucau caucgucauc cuccucuccc ucaucgccgu cggccuccuc     1620

cucuacugca aggcccgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7447
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7447
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gagugcuuua      240

agaacuggau gguacaccag cguuauuaca aucgaacugu ccaacauuaa ggagaauaaa      300

ugcaacggua ccgacgccaa ggugaaacua aucaagcagg aacucgauaa guauaaaaau      360

gcaguaacug agcugcagau gcuuaugugu ucuacacccg ccaccggcuc ggggucagcu      420

auagcaagcg gaguggccgu cugcaaggug cugcacuugg agggcgaagu uaacaaaauc      480

aagagugcuc uccuguccac gaauaaagcc guggucucuc ugagcaacgg uguguccgua      540

cucacuuuua agguuuuaga ccugaagaau uacauugaua aacagcuuuu gccuauccug      600

aacaagcaau cauguaguau uagcaauauc gagaccguga uggaguucca gcagaaaaac      660

aauaggcuac ucgaaauaac acgggaguuu ucugucaacg cgggggugac uaccccagug      720

uccacauaua ugcugaccaa uucagaacuu cugagcuuga uuaacgacau gccgaucacg      780

aacgaucaga agaaacucau gaguaauaac guccaaauug uucgccagca gucuuacucc      840

aucaugugca ucauuaagga ggaagugcug gcauauguag ugcaguuacc ccuguacgga      900

gucauagaca cuccuuguug gaaacuccau acaagcccac uuugcaccac uaauacaaag      960

gagggcucga acaucugucu gacccgaacg gaucguggcu gguacugcga caaugccggg     1020

ucuguguccu ucuuucccca agcugaaacc uguaagguuu gcucaaacag aguguucugc     1080

gauacaauga auaguuugac ucuaccuagc gaggucaacc uguguaaugu ggacauuuuu     1140

aacccaaaau augauugcaa gaucaugacc uccaaaacag acguaucuag cucaguuaua     1200

acuagccucg gagccauugu guccuguuac gguaagacca aaugcacagc aagcaauaag     1260

aacaagggca ucaucaaaac cuucucuaau gggugugauu augucucaaa caagggagug     1320

gacacuguca gugugggcaa uacgcuguac uauguuaaca aacaggaggg uaagagccuu     1380

uacgugaaag gggaacccau uaucaacuuu uaugacccuc ugguauuccc auccgaugag     1440

uuugacgcuu cuauuucgca ggucaaugaa aagauaaacc aaaguuuggc cuucaucagg     1500

aaguccgaug agcuccugca caaugugaac gcgggaaaau caacaaccaa uauuaugauc     1560

acuaccauca uuauaguuau cauugugauc uuacugaguc uaauugccgu cggccuccug     1620

cuuuacugca aggcacggug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7448
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7448
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gagcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaacaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg agcugcagau gcugaugugc agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcaacgg cgugagcgug      540

cugaccuuca aggugcugga ccugaagaac uacaucgaca agcagcugcu gcccauccug      600

aacaagcaga gcugcagcau cagcaacauc gagaccguga uggaguucca gcagaagaac      660

aacagacugc uggagaucac cagagaguuc agcgugaacg ccggcgugac cacccccgug      720

agcaccuaca ugcugaccaa cagcgagcug cugagccuga ucaacgacau gcccaucacc      780

aacgaccaga agaagcugau gagcaacaac gugcagaucg ugagacagca gagcuacagc      840

aucaugugca ucaucaagga ggaggugcug gccuacgugg ugcagcugcc ccuguacggc      900

gugaucgaca cccccugcug gaagcugcac accagccccc ugugcaccac caacaccaag      960

gagggcagca acaucugccu gaccagaacc gacagaggcu gguacugcga caacgccggc     1020

agcgugagcu ucuuccccca ggccgagacc ugcaaggugu gcagcaacag aguguucugc     1080

gacaccauga acagccugac ccugcccagc gaggugaacc ugugcaacgu ggacaucuuc     1140

aaccccaagu acgacugcaa gaucaugacc agcaagaccg acgugagcag cagcgugauc     1200

accagccugg gcgccaucgu gagcugcuac ggcaagacca agugcaccgc cagcaacaag     1260

aacaagggca ucaucaagac cuucagcaac ggcugcgacu acgugagcaa caagggcgug     1320

gacaccguga gcgugggcaa cacccuguac uacgugaaca agcaggaggg caagagccug     1380

uacgugaagg gcgagcccau caucaacuuc uacgaccccc ugguguuccc cagcgacgag     1440

uucgacgcca gcaucagcca ggugaacgag aagaucaacc agagccuggc cuucaucaga     1500

aagagcgacg agcugcugca caacgugaac gccggcaaga gcaccaccaa caucaugauc     1560

accaccauca ucaucgugau caucgugauc cugcugagcc ugaucgccgu gggccugcug     1620

cuguacugca aggccagaug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7449
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7449
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu guccgcccuc      240

agaacaggau gguacaccuc uguuaucaca auugaacuga gcaacaucaa ggagaauaaa      300

ugcaacggca ccgacgccaa ggugaaacuu aucaagcagg aacuggauaa guauaaaaau      360

gcugugacgg agcuccagau gcugaugugu uccacccccg ccacaggguc uggaagcgcu      420

auugccuccg gcgucgcggu gugcaagguu cugcaccucg agggggaagu gaacaaaauc      480

aagagcgccc ugcuuucuac caauaaagcu gucguguccc ugagcaacgg aguuucugug      540

cucacauuua agguccugga ccuuaagaau uacauugaua aacagcugcu cccuauccug      600

aacaagcaau ccuguagcau uucuaauauc gagaccguga uggaguucca gcagaaaaac      660

aaucggcugc ucgaaauuac gcgcgaguuu uccgugaacg ccggcgucac aaccccgguu      720

agcacauaua ugcugaccaa uuccgaacuu cugucucuca ucaacgacau gcccaucacc      780

aacgaucaga agaaacugau gagcaauaac gugcaaauug ugagacagca guccuacagc      840

aucaugugca uuaucaagga ggaaguccuu gcuuaugugg uucagcugcc ucucuacggc      900

gugauugaca cacccuguug gaaacugcau acgucuccuc ugugcaccac aaauaccaag      960

gaggggucca acaucugucu cacacggacc gaucgcggau gguacugcga caaugccggc     1020

agcgucucuu ucuuucccca agcggaaacg uguaaggugu gcagcaacag aguuuucugc     1080

gauacaauga acucccugac ccuuccuucu gaggugaauc uguguaaugu cgacaucuuu     1140

aacccgaaau augauugcaa gauuaugacc agcaaaacag acguguccag cucugucauc     1200

accucccucg gggccauugu gagcuguuac ggaaagacaa aaugcacggc uucuaauaag     1260

aacaagggca ucauuaaaac cuucuccaau gggugugauu auguuagcaa caagggagug     1320

gacacagucu ccgugggcaa uacccuguac uauguuaaca aacaggaggg caagucucuu     1380

uacgugaaag gggaacccau caucaacuuu uaugacccuc uggucuuccc cagcgaugag     1440

uuugacgccu ccauuucuca ggugaaugaa aagaucaacc aaagccucgc uuucauucgg     1500

aaguccgaug agcugcugca caaugugaac gccggaaaaa gcacaaccaa uaucaugauu     1560

acgaccauca uuaucguuau cauugucauc cuccugucuc uuauugccgu gggccugcuc     1620

cuguacugca aggcucgcug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7450
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7450
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aauuacuaau ccucaaagca      120

aacgcaauua caaccauacu aaccgcuguc accuuuuguu uugccucagg acaaaacaua      180

acugaagaau uuuaccaauc aacaugcucc gcaguaucua aaggauaccu cagcgcguua      240

agaacaggau gguacacauc gguaauaacc aucgaauuau ccaacauaaa agaaaauaaa      300

ugcaauggaa cagacgcaaa agucaaauua auuaaacaag aacuagacaa auauaaaaac      360

gcaguaaccg aauuacaaau gcuaaugugu ucaacaccag caacaggauc aggaucagcu      420

auagcuucag gaguugccgu augcaaagug cuacacuuag aaggagaagu gaauaaaaua      480

aaaucagcuc uauuaucaac gaacaaagcc guaguaucuc uaucaaaugg cguaucagua      540

cucacauuca aaguacucga ccuaaaaaac uauauagaua aacaacuauu acccauccua      600

aauaaacaaa gcugcucuau aucaaacauc gaaacaguaa uggaauuuca acaaaaaaac      660

aacagacuac uagaaauaac ccgagaguuc ucaguuaaug caggaguaac aacaccaguc      720

ucaacauaca ugcucacaaa cucagaacuc cuaucacuaa uaaaugacau gccaauaaca      780

aacgaccaaa aaaaacucau gucuaacaac guccaaauag uaagacaaca auccuacagc      840

auaaugugua uaauaaaaga agaaguuuua gcauacgucg uacaacuacc cuuauauggc      900

guaauagaua caccaugcug gaaacuccau accucaccuc uauguacaac aaauaccaaa      960

gaagguucua auauaugccu aacacgaacu gaccgaggau gguacuguga caacgcagga     1020

ucagucucuu ucuuuccaca agcagaaacc ugcaaaguau gcaguaaccg cguauuuugc     1080

gacacaauga acucccuaac cuuaccauca gaaguaaacu uauguaacgu agacauauuc     1140

aauccaaaau augacugcaa aauaaugaca ucaaaaacag acguaagcuc aucaguaaua     1200

acuucacuag gcgcaauugu aucaugcuau ggaaaaacca aauguaccgc auccaacaaa     1260

aauaaaggaa uaauaaaaac cuucucuaac ggaugcgacu acguaucaaa caaaggugua     1320

gauacaguuu cuguaggaaa cacacucuac uauguaaaua aacaagaagg aaaaucacua     1380

uacguaaaag gagaaccaau aauaaacuuc uaugacccac uuguauuucc aucugaugaa     1440

uuugaugcaa gcauaucaca aguaaacgaa aaaauaaacc aaucucuagc cuuuauacga     1500

aaaagcgacg aauuacuaca uaacgucaac gcuggaaaau caacaacaaa cauaaugaua     1560

acaacaauaa uaauaguaau aauagucauc cuauuaucac uaaucgccgu aggacuacuc     1620

cuauacugca aagcuagaua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7451
<211>  2136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7451
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauaa ccacuauccu cacagcaguc acuuucugcu ucgccucagg acaaaacaua      180

accgaagagu ucuaccaauc cacaugcucc gccgucucca aaggcuaccu cucagcgcuc      240

cgcaccggcu gguacacauc cgucaucacc aucgaacuaa gcaacauaaa agaaaacaaa      300

ugcaacggca ccgacgccaa aguuaaacuc aucaagcaag aacucgacaa auacaaaaac      360

gcagucacag aacuucaaau gcucaugugc uccacacccg ccacagguuc uggcucagca      420

aucgcaagcg gcgucgccgu augcaaaguc cuucaccucg aaggcgaagu caacaaaauc      480

aaauccgccc uccucuccac caauaaagcu gucgucucac ucuccaacgg cgucagcguc      540

cucacauuca aaguccucga ccucaaaaac uacauagaca agcaacuccu cccgauacuc      600

aacaaacaaa gcugcucuau cuccaacauc gaaaccguca uggaguucca acagaaaaac      660

aaucgucucc ucgaaaucac ccgcgaguuc ucaguaaacg ccggggucac cacaccaguc      720

uccaccuaca ugcucaccaa cuccgaacuc cuuagccuca uaaacgacau gcccauaacc      780

aacgaccaaa agaaacucau gagcaacaac guacaaauag uccgacaaca auccuauucc      840

aucaugugua ucaucaaaga agaaguccuc gcauacguag uccaacuccc ccuauacggc      900

guaaucgaca ccccauguug gaaacuccac accucaccac ucuguaccac caacaccaaa      960

gaaggcucaa acaucugccu cacccgcaca gaccgcggcu gguacugcga caacgcgggc     1020

uccgucagcu ucuuucccca agcggaaacc ugcaaagucu gcagcaacag agucuucugc     1080

gacacuauga acucccucac ccuccccuca gaagucaacc ucugcaacgu cgacaucuuc     1140

aacccgaaau acgacugcaa aaucaugacc agcaaaacug acgucuccuc guccgucauc     1200

accucacucg gcgcaaucgu gagcugcuac ggcaaaacca aaugcaccgc cuccaacaaa     1260

aacaaaggca ucauaaaaac auucagcaac ggcugcgacu acgucucgaa caaaggaguc     1320

gacaccguau cagugggcaa cacccuauac uacguaaaca agcaagaagg caaaucacuc     1380

uacguaaaag gcgaacccau caucaacuuc uacgaccccc ucgucuuccc cuccgacgag     1440

uucgacgccu ccaucucuca agucaacgag aaaaucaacc aaucccuugc cuucauacgu     1500

aaaagcgacg aacuccuuca caacguaaac gccgggaaau ccaccacuaa cauaaugauc     1560

accaccauca ucaucguuau cauagucauc cuccucucuc ucauagcagu cggccuacuc     1620

cuguacugca aagcgcgcua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1680

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1740

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1800

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1860

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1920

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1980

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2100

ccccccccaa aggcucuuuu cagagccacc agaauu                               2136


<210>  7452
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7452
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag      660

acggugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      720

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      900

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      960

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac     1020

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc     1080

aaggugugca gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1140

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1260

aagacgaagu gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac     1440

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1500

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1560

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1620

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7453
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7453
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc      420

acccccgcca ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug      480

caccuggagg gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug      540

gucucccuga gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac      600

aucgacaagc agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc      720

gugaacgccg gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug      780

ucccugauca acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug      840

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggucc agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac     1020

cggggguggu acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag     1140

gucaaccucu gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc     1200

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg     1320

ugcgacuacg ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac     1380

gucaacaagc aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1500

aucaaccagu cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc     1560

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug     1620

cucagccuga ucgccguggg ccugcuccug uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7454
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7454
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      600

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag      660

accgucaugg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      720

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      780

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      840

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      900

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      960

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac     1020

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc     1080

aaggucugcu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1140

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1200

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1260

aagaccaagu gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc     1320

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1380

gucaacaagc aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1500

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1560

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1620

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7455
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7455
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc      300

gaacugucca acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc      360

aagcaggaac ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu      420

acacccgcca ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug      480

cacuuggagg gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug      540

gucucucuga gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac      600

auugauaaac agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag      660

accgugaugg aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu      720

gucaacgcgg gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug      780

agcuugauua acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc      840

caaauuguuc gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca      900

uauguagugc aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca      960

agcccacuuu gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau     1020

cguggcuggu acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu     1080

aagguuugcu caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag     1140

gucaaccugu guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc     1200

aaaacagacg uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu     1260

aagaccaaau gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg     1320

ugugauuaug ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau     1380

guuaacaaac aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau     1440

gacccucugg uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag     1500

auaaaccaaa guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg     1560

ggaaaaucaa caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua     1620

cugagucuaa uugccgucgg ccuccugcuu uacugcaagg cacggugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7456
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7456
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      600

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag      660

accgugaugg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      720

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      780

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      840

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      900

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      960

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac     1020

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc     1080

aaggugugca gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1140

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1200

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1260

aagaccaagu gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc     1320

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1380

gugaacaagc aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac     1440

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1500

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1560

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1620

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7457
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7457
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu      300

gaacugagca acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc      360

aagcaggaac uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc      420

acccccgcca cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug      480

caccucgagg gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc      540

gugucccuga gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac      600

auugauaaac agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag      660

accgugaugg aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc      720

gugaacgccg gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug      780

ucucucauca acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug      840

caaauuguga gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu      900

uaugugguuc agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg      960

ucuccucugu gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau     1020

cgcggauggu acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu     1080

aaggugugca gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag     1140

gugaaucugu guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc     1200

aaaacagacg uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga     1260

aagacaaaau gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg     1320

ugugauuaug uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau     1380

guuaacaaac aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau     1440

gacccucugg ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag     1500

aucaaccaaa gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc     1560

ggaaaaagca caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc     1620

cugucucuua uugccguggg ccugcuccug uacugcaagg cucgcugagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7458
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7458
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaau uacuaauccu caaagcaaac gcaauuacaa ccauacuaac cgcugucacc      180

uuuuguuuug ccucaggaca aaacauaacu gaagaauuuu accaaucaac augcuccgca      240

guaucuaaag gauaccucag cgcguuaaga acaggauggu acacaucggu aauaaccauc      300

gaauuaucca acauaaaaga aaauaaaugc aauggaacag acgcaaaagu caaauuaauu      360

aaacaagaac uagacaaaua uaaaaacgca guaaccgaau uacaaaugcu aauguguuca      420

acaccagcaa caggaucagg aucagcuaua gcuucaggag uugccguaug caaagugcua      480

cacuuagaag gagaagugaa uaaaauaaaa ucagcucuau uaucaacgaa caaagccgua      540

guaucucuau caaauggcgu aucaguacuc acauucaaag uacucgaccu aaaaaacuau      600

auagauaaac aacuauuacc cauccuaaau aaacaaagcu gcucuauauc aaacaucgaa      660

acaguaaugg aauuucaaca aaaaaacaac agacuacuag aaauaacccg agaguucuca      720

guuaaugcag gaguaacaac accagucuca acauacaugc ucacaaacuc agaacuccua      780

ucacuaauaa augacaugcc aauaacaaac gaccaaaaaa aacucauguc uaacaacguc      840

caaauaguaa gacaacaauc cuacagcaua auguguauaa uaaaagaaga aguuuuagca      900

uacgucguac aacuacccuu auauggcgua auagauacac caugcuggaa acuccauacc      960

ucaccucuau guacaacaaa uaccaaagaa gguucuaaua uaugccuaac acgaacugac     1020

cgaggauggu acugugacaa cgcaggauca gucucuuucu uuccacaagc agaaaccugc     1080

aaaguaugca guaaccgcgu auuuugcgac acaaugaacu cccuaaccuu accaucagaa     1140

guaaacuuau guaacguaga cauauucaau ccaaaauaug acugcaaaau aaugacauca     1200

aaaacagacg uaagcucauc aguaauaacu ucacuaggcg caauuguauc augcuaugga     1260

aaaaccaaau guaccgcauc caacaaaaau aaaggaauaa uaaaaaccuu cucuaacgga     1320

ugcgacuacg uaucaaacaa agguguagau acaguuucug uaggaaacac acucuacuau     1380

guaaauaaac aagaaggaaa aucacuauac guaaaaggag aaccaauaau aaacuucuau     1440

gacccacuug uauuuccauc ugaugaauuu gaugcaagca uaucacaagu aaacgaaaaa     1500

auaaaccaau cucuagccuu uauacgaaaa agcgacgaau uacuacauaa cgucaacgcu     1560

ggaaaaucaa caacaaacau aaugauaaca acaauaauaa uaguaauaau agucauccua     1620

uuaucacuaa ucgccguagg acuacuccua uacugcaaag cuagauaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7459
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7459
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccauaacca cuauccucac agcagucacu      180

uucugcuucg ccucaggaca aaacauaacc gaagaguucu accaauccac augcuccgcc      240

gucuccaaag gcuaccucuc agcgcuccgc accggcuggu acacauccgu caucaccauc      300

gaacuaagca acauaaaaga aaacaaaugc aacggcaccg acgccaaagu uaaacucauc      360

aagcaagaac ucgacaaaua caaaaacgca gucacagaac uucaaaugcu caugugcucc      420

acacccgcca cagguucugg cucagcaauc gcaagcggcg ucgccguaug caaaguccuu      480

caccucgaag gcgaagucaa caaaaucaaa uccgcccucc ucuccaccaa uaaagcuguc      540

gucucacucu ccaacggcgu cagcguccuc acauucaaag uccucgaccu caaaaacuac      600

auagacaagc aacuccuccc gauacucaac aaacaaagcu gcucuaucuc caacaucgaa      660

accgucaugg aguuccaaca gaaaaacaau cgucuccucg aaaucacccg cgaguucuca      720

guaaacgccg gggucaccac accagucucc accuacaugc ucaccaacuc cgaacuccuu      780

agccucauaa acgacaugcc cauaaccaac gaccaaaaga aacucaugag caacaacgua      840

caaauagucc gacaacaauc cuauuccauc auguguauca ucaaagaaga aguccucgca      900

uacguagucc aacucccccu auacggcgua aucgacaccc cauguuggaa acuccacacc      960

ucaccacucu guaccaccaa caccaaagaa ggcucaaaca ucugccucac ccgcacagac     1020

cgcggcuggu acugcgacaa cgcgggcucc gucagcuucu uuccccaagc ggaaaccugc     1080

aaagucugca gcaacagagu cuucugcgac acuaugaacu cccucacccu ccccucagaa     1140

gucaaccucu gcaacgucga caucuucaac ccgaaauacg acugcaaaau caugaccagc     1200

aaaacugacg ucuccucguc cgucaucacc ucacucggcg caaucgugag cugcuacggc     1260

aaaaccaaau gcaccgccuc caacaaaaac aaaggcauca uaaaaacauu cagcaacggc     1320

ugcgacuacg ucucgaacaa aggagucgac accguaucag ugggcaacac ccuauacuac     1380

guaaacaagc aagaaggcaa aucacucuac guaaaaggcg aacccaucau caacuucuac     1440

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucucaagu caacgagaaa     1500

aucaaccaau cccuugccuu cauacguaaa agcgacgaac uccuucacaa cguaaacgcc     1560

gggaaaucca ccacuaacau aaugaucacc accaucauca ucguuaucau agucauccuc     1620

cucucucuca uagcagucgg ccuacuccug uacugcaaag cgcgcuaagg acuaguaaua     1680

aggaaacugu augaaugucu gugggcagga agugaagaga uccuucugua aagguuuuug     1740

gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua aaucugguag aaaaaugaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7460
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7460
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7461
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7461
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7462
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7462
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7463
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7463
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7464
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7464
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7465
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7465
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7466
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7466
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccucaaa      120

gcaaacgcaa uuacaaccau acuaaccgcu gucaccuuuu guuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacaugc uccgcaguau cuaaaggaua ccucagcgcg      240

uuaagaacag gaugguacac aucgguaaua accaucgaau uauccaacau aaaagaaaau      300

aaaugcaaug gaacagacgc aaaagucaaa uuaauuaaac aagaacuaga caaauauaaa      360

aacgcaguaa ccgaauuaca aaugcuaaug uguucaacac cagcaacagg aucaggauca      420

gcuauagcuu caggaguugc cguaugcaaa gugcuacacu uagaaggaga agugaauaaa      480

auaaaaucag cucuauuauc aacgaacaaa gccguaguau cucuaucaaa uggcguauca      540

guacucacau ucaaaguacu cgaccuaaaa aacuauauag auaaacaacu auuacccauc      600

cuaaauaaac aaagcugcuc uauaucaaac aucgaaacag uaauggaauu ucaacaaaaa      660

aacaacagac uacuagaaau aacccgagag uucucaguua augcaggagu aacaacacca      720

gucucaacau acaugcucac aaacucagaa cuccuaucac uaauaaauga caugccaaua      780

acaaacgacc aaaaaaaacu caugucuaac aacguccaaa uaguaagaca acaauccuac      840

agcauaaugu guauaauaaa agaagaaguu uuagcauacg ucguacaacu acccuuauau      900

ggcguaauag auacaccaug cuggaaacuc cauaccucac cucuauguac aacaaauacc      960

aaagaagguu cuaauauaug ccuaacacga acugaccgag gaugguacug ugacaacgca     1020

ggaucagucu cuuucuuucc acaagcagaa accugcaaag uaugcaguaa ccgcguauuu     1080

ugcgacacaa ugaacucccu aaccuuacca ucagaaguaa acuuauguaa cguagacaua     1140

uucaauccaa aauaugacug caaaauaaug acaucaaaaa cagacguaag cucaucagua     1200

auaacuucac uaggcgcaau uguaucaugc uauggaaaaa ccaaauguac cgcauccaac     1260

aaaaauaaag gaauaauaaa aaccuucucu aacggaugcg acuacguauc aaacaaaggu     1320

guagauacag uuucuguagg aaacacacuc uacuauguaa auaaacaaga aggaaaauca     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cacuuguauu uccaucugau     1440

gaauuugaug caagcauauc acaaguaaac gaaaaaauaa accaaucucu agccuuuaua     1500

cgaaaaagcg acgaauuacu acauaacguc aacgcuggaa aaucaacaac aaacauaaug     1560

auaacaacaa uaauaauagu aauaauaguc auccuauuau cacuaaucgc cguaggacua     1620

cuccuauacu gcaaagcuag auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7467
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7467
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacuau ccucacagca gucacuuucu gcuucgccuc aggacaaaac      180

auaaccgaag aguucuacca auccacaugc uccgccgucu ccaaaggcua ccucucagcg      240

cuccgcaccg gcugguacac auccgucauc accaucgaac uaagcaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaaguuaaa cucaucaagc aagaacucga caaauacaaa      360

aacgcaguca cagaacuuca aaugcucaug ugcuccacac ccgccacagg uucuggcuca      420

gcaaucgcaa gcggcgucgc cguaugcaaa guccuucacc ucgaaggcga agucaacaaa      480

aucaaauccg cccuccucuc caccaauaaa gcugucgucu cacucuccaa cggcgucagc      540

guccucacau ucaaaguccu cgaccucaaa aacuacauag acaagcaacu ccucccgaua      600

cucaacaaac aaagcugcuc uaucuccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaucguc uccucgaaau cacccgcgag uucucaguaa acgccggggu caccacacca      720

gucuccaccu acaugcucac caacuccgaa cuccuuagcc ucauaaacga caugcccaua      780

accaacgacc aaaagaaacu caugagcaac aacguacaaa uaguccgaca acaauccuau      840

uccaucaugu guaucaucaa agaagaaguc cucgcauacg uaguccaacu cccccuauac      900

ggcguaaucg acaccccaug uuggaaacuc cacaccucac cacucuguac caccaacacc      960

aaagaaggcu caaacaucug ccucacccgc acagaccgcg gcugguacug cgacaacgcg     1020

ggcuccguca gcuucuuucc ccaagcggaa accugcaaag ucugcagcaa cagagucuuc     1080

ugcgacacua ugaacucccu cacccucccc ucagaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaaucaug accagcaaaa cugacgucuc cucguccguc     1200

aucaccucac ucggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aacauucagc aacggcugcg acuacgucuc gaacaaagga     1320

gucgacaccg uaucaguggg caacacccua uacuacguaa acaagcaaga aggcaaauca     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ucaagucaac gagaaaauca accaaucccu ugccuucaua     1500

cguaaaagcg acgaacuccu ucacaacgua aacgccggga aauccaccac uaacauaaug     1560

aucaccacca ucaucaucgu uaucauaguc auccuccucu cucucauagc agucggccua     1620

cuccuguacu gcaaagcgcg cuaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  7468
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7468
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7469
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7469
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7470
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7470
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7471
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7471
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7472
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7472
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7473
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7473
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7474
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7474
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccucaaa      120

gcaaacgcaa uuacaaccau acuaaccgcu gucaccuuuu guuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacaugc uccgcaguau cuaaaggaua ccucagcgcg      240

uuaagaacag gaugguacac aucgguaaua accaucgaau uauccaacau aaaagaaaau      300

aaaugcaaug gaacagacgc aaaagucaaa uuaauuaaac aagaacuaga caaauauaaa      360

aacgcaguaa ccgaauuaca aaugcuaaug uguucaacac cagcaacagg aucaggauca      420

gcuauagcuu caggaguugc cguaugcaaa gugcuacacu uagaaggaga agugaauaaa      480

auaaaaucag cucuauuauc aacgaacaaa gccguaguau cucuaucaaa uggcguauca      540

guacucacau ucaaaguacu cgaccuaaaa aacuauauag auaaacaacu auuacccauc      600

cuaaauaaac aaagcugcuc uauaucaaac aucgaaacag uaauggaauu ucaacaaaaa      660

aacaacagac uacuagaaau aacccgagag uucucaguua augcaggagu aacaacacca      720

gucucaacau acaugcucac aaacucagaa cuccuaucac uaauaaauga caugccaaua      780

acaaacgacc aaaaaaaacu caugucuaac aacguccaaa uaguaagaca acaauccuac      840

agcauaaugu guauaauaaa agaagaaguu uuagcauacg ucguacaacu acccuuauau      900

ggcguaauag auacaccaug cuggaaacuc cauaccucac cucuauguac aacaaauacc      960

aaagaagguu cuaauauaug ccuaacacga acugaccgag gaugguacug ugacaacgca     1020

ggaucagucu cuuucuuucc acaagcagaa accugcaaag uaugcaguaa ccgcguauuu     1080

ugcgacacaa ugaacucccu aaccuuacca ucagaaguaa acuuauguaa cguagacaua     1140

uucaauccaa aauaugacug caaaauaaug acaucaaaaa cagacguaag cucaucagua     1200

auaacuucac uaggcgcaau uguaucaugc uauggaaaaa ccaaauguac cgcauccaac     1260

aaaaauaaag gaauaauaaa aaccuucucu aacggaugcg acuacguauc aaacaaaggu     1320

guagauacag uuucuguagg aaacacacuc uacuauguaa auaaacaaga aggaaaauca     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cacuuguauu uccaucugau     1440

gaauuugaug caagcauauc acaaguaaac gaaaaaauaa accaaucucu agccuuuaua     1500

cgaaaaagcg acgaauuacu acauaacguc aacgcuggaa aaucaacaac aaacauaaug     1560

auaacaacaa uaauaauagu aauaauaguc auccuauuau cacuaaucgc cguaggacua     1620

cuccuauacu gcaaagcuag auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7475
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7475
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacuau ccucacagca gucacuuucu gcuucgccuc aggacaaaac      180

auaaccgaag aguucuacca auccacaugc uccgccgucu ccaaaggcua ccucucagcg      240

cuccgcaccg gcugguacac auccgucauc accaucgaac uaagcaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaaguuaaa cucaucaagc aagaacucga caaauacaaa      360

aacgcaguca cagaacuuca aaugcucaug ugcuccacac ccgccacagg uucuggcuca      420

gcaaucgcaa gcggcgucgc cguaugcaaa guccuucacc ucgaaggcga agucaacaaa      480

aucaaauccg cccuccucuc caccaauaaa gcugucgucu cacucuccaa cggcgucagc      540

guccucacau ucaaaguccu cgaccucaaa aacuacauag acaagcaacu ccucccgaua      600

cucaacaaac aaagcugcuc uaucuccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaucguc uccucgaaau cacccgcgag uucucaguaa acgccggggu caccacacca      720

gucuccaccu acaugcucac caacuccgaa cuccuuagcc ucauaaacga caugcccaua      780

accaacgacc aaaagaaacu caugagcaac aacguacaaa uaguccgaca acaauccuau      840

uccaucaugu guaucaucaa agaagaaguc cucgcauacg uaguccaacu cccccuauac      900

ggcguaaucg acaccccaug uuggaaacuc cacaccucac cacucuguac caccaacacc      960

aaagaaggcu caaacaucug ccucacccgc acagaccgcg gcugguacug cgacaacgcg     1020

ggcuccguca gcuucuuucc ccaagcggaa accugcaaag ucugcagcaa cagagucuuc     1080

ugcgacacua ugaacucccu cacccucccc ucagaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaaucaug accagcaaaa cugacgucuc cucguccguc     1200

aucaccucac ucggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aacauucagc aacggcugcg acuacgucuc gaacaaagga     1320

gucgacaccg uaucaguggg caacacccua uacuacguaa acaagcaaga aggcaaauca     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ucaagucaac gagaaaauca accaaucccu ugccuucaua     1500

cguaaaagcg acgaacuccu ucacaacgua aacgccggga aauccaccac uaacauaaug     1560

aucaccacca ucaucaucgu uaucauaguc auccuccucu cucucauagc agucggccua     1620

cuccuguacu gcaaagcgcg cuaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  7476
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7476
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7477
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7477
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7478
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7478
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7479
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7479
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7480
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7480
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7481
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7481
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7482
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7482
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccucaaa      120

gcaaacgcaa uuacaaccau acuaaccgcu gucaccuuuu guuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacaugc uccgcaguau cuaaaggaua ccucagcgcg      240

uuaagaacag gaugguacac aucgguaaua accaucgaau uauccaacau aaaagaaaau      300

aaaugcaaug gaacagacgc aaaagucaaa uuaauuaaac aagaacuaga caaauauaaa      360

aacgcaguaa ccgaauuaca aaugcuaaug uguucaacac cagcaacagg aucaggauca      420

gcuauagcuu caggaguugc cguaugcaaa gugcuacacu uagaaggaga agugaauaaa      480

auaaaaucag cucuauuauc aacgaacaaa gccguaguau cucuaucaaa uggcguauca      540

guacucacau ucaaaguacu cgaccuaaaa aacuauauag auaaacaacu auuacccauc      600

cuaaauaaac aaagcugcuc uauaucaaac aucgaaacag uaauggaauu ucaacaaaaa      660

aacaacagac uacuagaaau aacccgagag uucucaguua augcaggagu aacaacacca      720

gucucaacau acaugcucac aaacucagaa cuccuaucac uaauaaauga caugccaaua      780

acaaacgacc aaaaaaaacu caugucuaac aacguccaaa uaguaagaca acaauccuac      840

agcauaaugu guauaauaaa agaagaaguu uuagcauacg ucguacaacu acccuuauau      900

ggcguaauag auacaccaug cuggaaacuc cauaccucac cucuauguac aacaaauacc      960

aaagaagguu cuaauauaug ccuaacacga acugaccgag gaugguacug ugacaacgca     1020

ggaucagucu cuuucuuucc acaagcagaa accugcaaag uaugcaguaa ccgcguauuu     1080

ugcgacacaa ugaacucccu aaccuuacca ucagaaguaa acuuauguaa cguagacaua     1140

uucaauccaa aauaugacug caaaauaaug acaucaaaaa cagacguaag cucaucagua     1200

auaacuucac uaggcgcaau uguaucaugc uauggaaaaa ccaaauguac cgcauccaac     1260

aaaaauaaag gaauaauaaa aaccuucucu aacggaugcg acuacguauc aaacaaaggu     1320

guagauacag uuucuguagg aaacacacuc uacuauguaa auaaacaaga aggaaaauca     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cacuuguauu uccaucugau     1440

gaauuugaug caagcauauc acaaguaaac gaaaaaauaa accaaucucu agccuuuaua     1500

cgaaaaagcg acgaauuacu acauaacguc aacgcuggaa aaucaacaac aaacauaaug     1560

auaacaacaa uaauaauagu aauaauaguc auccuauuau cacuaaucgc cguaggacua     1620

cuccuauacu gcaaagcuag auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7483
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7483
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacuau ccucacagca gucacuuucu gcuucgccuc aggacaaaac      180

auaaccgaag aguucuacca auccacaugc uccgccgucu ccaaaggcua ccucucagcg      240

cuccgcaccg gcugguacac auccgucauc accaucgaac uaagcaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaaguuaaa cucaucaagc aagaacucga caaauacaaa      360

aacgcaguca cagaacuuca aaugcucaug ugcuccacac ccgccacagg uucuggcuca      420

gcaaucgcaa gcggcgucgc cguaugcaaa guccuucacc ucgaaggcga agucaacaaa      480

aucaaauccg cccuccucuc caccaauaaa gcugucgucu cacucuccaa cggcgucagc      540

guccucacau ucaaaguccu cgaccucaaa aacuacauag acaagcaacu ccucccgaua      600

cucaacaaac aaagcugcuc uaucuccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaucguc uccucgaaau cacccgcgag uucucaguaa acgccggggu caccacacca      720

gucuccaccu acaugcucac caacuccgaa cuccuuagcc ucauaaacga caugcccaua      780

accaacgacc aaaagaaacu caugagcaac aacguacaaa uaguccgaca acaauccuau      840

uccaucaugu guaucaucaa agaagaaguc cucgcauacg uaguccaacu cccccuauac      900

ggcguaaucg acaccccaug uuggaaacuc cacaccucac cacucuguac caccaacacc      960

aaagaaggcu caaacaucug ccucacccgc acagaccgcg gcugguacug cgacaacgcg     1020

ggcuccguca gcuucuuucc ccaagcggaa accugcaaag ucugcagcaa cagagucuuc     1080

ugcgacacua ugaacucccu cacccucccc ucagaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaaucaug accagcaaaa cugacgucuc cucguccguc     1200

aucaccucac ucggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aacauucagc aacggcugcg acuacgucuc gaacaaagga     1320

gucgacaccg uaucaguggg caacacccua uacuacguaa acaagcaaga aggcaaauca     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ucaagucaac gagaaaauca accaaucccu ugccuucaua     1500

cguaaaagcg acgaacuccu ucacaacgua aacgccggga aauccaccac uaacauaaug     1560

aucaccacca ucaucaucgu uaucauaguc auccuccucu cucucauagc agucggccua     1620

cuccuguacu gcaaagcgcg cuaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  7484
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7484
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcugaug ugcuccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccaa cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc caucagcaac aucgagacgg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugugcagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagaacaagg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggcaagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7485
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7485
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucagcgcc      240

cugcgcaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggagcugca gaugcucaug ugcuccaccc ccgccaccgg cagcgggucc      420

gccaucgcca gcggcguggc ggugugcaag guccugcacc uggagggcga ggugaacaag      480

aucaaguccg cccuccugag caccaacaag gccguggucu cccugagcaa cggggugucc      540

gugcucacgu ucaagguccu ggaccugaag aacuacaucg acaagcagcu ccugccgauc      600

cugaacaagc agagcugcuc caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcugac caacagcgag cuccuguccc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu gccccucuac      900

ggggugaucg acacgccgug cuggaagcug cacaccagcc cccugugcac caccaacacg      960

aaggagggca gcaacaucug ccucacccgc accgaccggg ggugguacug cgacaacgcg     1020

ggcuccguga gcuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccugccc uccgagguca accucugcaa cguggacauc     1140

uucaacccga aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacgggugcg acuacgugag caacaagggc     1320

gucgacacgg ugagcguggg caacacccug uacuacguca acaagcagga ggggaagucc     1380

cucuacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu ggcguucauc     1500

cggaaguccg acgagcuccu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccugcuca gccugaucgc cgugggccug     1620

cuccuguacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7486
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7486
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucuccgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgagcucca gaugcucaug ugcuccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccaa cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc caucuccaac aucgagaccg ucauggaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg ucugcuccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagaacaagg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggcaagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7487
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7487
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugagugcu      240

uuaagaacug gaugguacac cagcguuauu acaaucgaac uguccaacau uaaggagaau      300

aaaugcaacg guaccgacgc caaggugaaa cuaaucaagc aggaacucga uaaguauaaa      360

aaugcaguaa cugagcugca gaugcuuaug uguucuacac ccgccaccgg cucgggguca      420

gcuauagcaa gcggaguggc cgucugcaag gugcugcacu uggagggcga aguuaacaaa      480

aucaagagug cucuccuguc cacgaauaaa gccguggucu cucugagcaa cggugugucc      540

guacucacuu uuaagguuuu agaccugaag aauuacauug auaaacagcu uuugccuauc      600

cugaacaagc aaucauguag uauuagcaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaauaggc uacucgaaau aacacgggag uuuucuguca acgcgggggu gacuacccca      720

guguccacau auaugcugac caauucagaa cuucugagcu ugauuaacga caugccgauc      780

acgaacgauc agaagaaacu caugaguaau aacguccaaa uuguucgcca gcagucuuac      840

uccaucaugu gcaucauuaa ggaggaagug cuggcauaug uagugcaguu accccuguac      900

ggagucauag acacuccuug uuggaaacuc cauacaagcc cacuuugcac cacuaauaca      960

aaggagggcu cgaacaucug ucugacccga acggaucgug gcugguacug cgacaaugcc     1020

gggucugugu ccuucuuucc ccaagcugaa accuguaagg uuugcucaaa cagaguguuc     1080

ugcgauacaa ugaauaguuu gacucuaccu agcgagguca accuguguaa uguggacauu     1140

uuuaacccaa aauaugauug caagaucaug accuccaaaa cagacguauc uagcucaguu     1200

auaacuagcc ucggagccau uguguccugu uacgguaaga ccaaaugcac agcaagcaau     1260

aagaacaagg gcaucaucaa aaccuucucu aaugggugug auuaugucuc aaacaaggga     1320

guggacacug ucaguguggg caauacgcug uacuauguua acaaacagga ggguaagagc     1380

cuuuacguga aaggggaacc cauuaucaac uuuuaugacc cucugguauu cccauccgau     1440

gaguuugacg cuucuauuuc gcaggucaau gaaaagauaa accaaaguuu ggccuucauc     1500

aggaaguccg augagcuccu gcacaaugug aacgcgggaa aaucaacaac caauauuaug     1560

aucacuacca ucauuauagu uaucauugug aucuuacuga gucuaauugc cgucggccuc     1620

cugcuuuacu gcaaggcacg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7488
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7488
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugagcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagaac      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgagcugca gaugcugaug ugcagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcaa cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag caucagcaac aucgagaccg ugauggaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugugcagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagaacaagg gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggcaagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7489
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7489
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucuguccgcc      240

cucagaacag gaugguacac cucuguuauc acaauugaac ugagcaacau caaggagaau      300

aaaugcaacg gcaccgacgc caaggugaaa cuuaucaagc aggaacugga uaaguauaaa      360

aaugcuguga cggagcucca gaugcugaug uguuccaccc ccgccacagg gucuggaagc      420

gcuauugccu ccggcgucgc ggugugcaag guucugcacc ucgaggggga agugaacaaa      480

aucaagagcg cccugcuuuc uaccaauaaa gcugucgugu cccugagcaa cggaguuucu      540

gugcucacau uuaagguccu ggaccuuaag aauuacauug auaaacagcu gcucccuauc      600

cugaacaagc aauccuguag cauuucuaau aucgagaccg ugauggaguu ccagcagaaa      660

aacaaucggc ugcucgaaau uacgcgcgag uuuuccguga acgccggcgu cacaaccccg      720

guuagcacau auaugcugac caauuccgaa cuucugucuc ucaucaacga caugcccauc      780

accaacgauc agaagaaacu gaugagcaau aacgugcaaa uugugagaca gcaguccuac      840

agcaucaugu gcauuaucaa ggaggaaguc cuugcuuaug ugguucagcu gccucucuac      900

ggcgugauug acacacccug uuggaaacug cauacgucuc cucugugcac cacaaauacc      960

aaggaggggu ccaacaucug ucucacacgg accgaucgcg gaugguacug cgacaaugcc     1020

ggcagcgucu cuuucuuucc ccaagcggaa acguguaagg ugugcagcaa cagaguuuuc     1080

ugcgauacaa ugaacucccu gacccuuccu ucugagguga aucuguguaa ugucgacauc     1140

uuuaacccga aauaugauug caagauuaug accagcaaaa cagacguguc cagcucuguc     1200

aucaccuccc ucggggccau ugugagcugu uacggaaaga caaaaugcac ggcuucuaau     1260

aagaacaagg gcaucauuaa aaccuucucc aaugggugug auuauguuag caacaaggga     1320

guggacacag ucuccguggg caauacccug uacuauguua acaaacagga gggcaagucu     1380

cuuuacguga aaggggaacc caucaucaac uuuuaugacc cucuggucuu ccccagcgau     1440

gaguuugacg ccuccauuuc ucaggugaau gaaaagauca accaaagccu cgcuuucauu     1500

cggaaguccg augagcugcu gcacaaugug aacgccggaa aaagcacaac caauaucaug     1560

auuacgacca ucauuaucgu uaucauuguc auccuccugu cucuuauugc cgugggccug     1620

cuccuguacu gcaaggcucg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7490
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7490
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaauuacu aauccucaaa      120

gcaaacgcaa uuacaaccau acuaaccgcu gucaccuuuu guuuugccuc aggacaaaac      180

auaacugaag aauuuuacca aucaacaugc uccgcaguau cuaaaggaua ccucagcgcg      240

uuaagaacag gaugguacac aucgguaaua accaucgaau uauccaacau aaaagaaaau      300

aaaugcaaug gaacagacgc aaaagucaaa uuaauuaaac aagaacuaga caaauauaaa      360

aacgcaguaa ccgaauuaca aaugcuaaug uguucaacac cagcaacagg aucaggauca      420

gcuauagcuu caggaguugc cguaugcaaa gugcuacacu uagaaggaga agugaauaaa      480

auaaaaucag cucuauuauc aacgaacaaa gccguaguau cucuaucaaa uggcguauca      540

guacucacau ucaaaguacu cgaccuaaaa aacuauauag auaaacaacu auuacccauc      600

cuaaauaaac aaagcugcuc uauaucaaac aucgaaacag uaauggaauu ucaacaaaaa      660

aacaacagac uacuagaaau aacccgagag uucucaguua augcaggagu aacaacacca      720

gucucaacau acaugcucac aaacucagaa cuccuaucac uaauaaauga caugccaaua      780

acaaacgacc aaaaaaaacu caugucuaac aacguccaaa uaguaagaca acaauccuac      840

agcauaaugu guauaauaaa agaagaaguu uuagcauacg ucguacaacu acccuuauau      900

ggcguaauag auacaccaug cuggaaacuc cauaccucac cucuauguac aacaaauacc      960

aaagaagguu cuaauauaug ccuaacacga acugaccgag gaugguacug ugacaacgca     1020

ggaucagucu cuuucuuucc acaagcagaa accugcaaag uaugcaguaa ccgcguauuu     1080

ugcgacacaa ugaacucccu aaccuuacca ucagaaguaa acuuauguaa cguagacaua     1140

uucaauccaa aauaugacug caaaauaaug acaucaaaaa cagacguaag cucaucagua     1200

auaacuucac uaggcgcaau uguaucaugc uauggaaaaa ccaaauguac cgcauccaac     1260

aaaaauaaag gaauaauaaa aaccuucucu aacggaugcg acuacguauc aaacaaaggu     1320

guagauacag uuucuguagg aaacacacuc uacuauguaa auaaacaaga aggaaaauca     1380

cuauacguaa aaggagaacc aauaauaaac uucuaugacc cacuuguauu uccaucugau     1440

gaauuugaug caagcauauc acaaguaaac gaaaaaauaa accaaucucu agccuuuaua     1500

cgaaaaagcg acgaauuacu acauaacguc aacgcuggaa aaucaacaac aaacauaaug     1560

auaacaacaa uaauaauagu aauaauaguc auccuauuau cacuaaucgc cguaggacua     1620

cuccuauacu gcaaagcuag auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7491
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7491
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca uaaccacuau ccucacagca gucacuuucu gcuucgccuc aggacaaaac      180

auaaccgaag aguucuacca auccacaugc uccgccgucu ccaaaggcua ccucucagcg      240

cuccgcaccg gcugguacac auccgucauc accaucgaac uaagcaacau aaaagaaaac      300

aaaugcaacg gcaccgacgc caaaguuaaa cucaucaagc aagaacucga caaauacaaa      360

aacgcaguca cagaacuuca aaugcucaug ugcuccacac ccgccacagg uucuggcuca      420

gcaaucgcaa gcggcgucgc cguaugcaaa guccuucacc ucgaaggcga agucaacaaa      480

aucaaauccg cccuccucuc caccaauaaa gcugucgucu cacucuccaa cggcgucagc      540

guccucacau ucaaaguccu cgaccucaaa aacuacauag acaagcaacu ccucccgaua      600

cucaacaaac aaagcugcuc uaucuccaac aucgaaaccg ucauggaguu ccaacagaaa      660

aacaaucguc uccucgaaau cacccgcgag uucucaguaa acgccggggu caccacacca      720

gucuccaccu acaugcucac caacuccgaa cuccuuagcc ucauaaacga caugcccaua      780

accaacgacc aaaagaaacu caugagcaac aacguacaaa uaguccgaca acaauccuau      840

uccaucaugu guaucaucaa agaagaaguc cucgcauacg uaguccaacu cccccuauac      900

ggcguaaucg acaccccaug uuggaaacuc cacaccucac cacucuguac caccaacacc      960

aaagaaggcu caaacaucug ccucacccgc acagaccgcg gcugguacug cgacaacgcg     1020

ggcuccguca gcuucuuucc ccaagcggaa accugcaaag ucugcagcaa cagagucuuc     1080

ugcgacacua ugaacucccu cacccucccc ucagaaguca accucugcaa cgucgacauc     1140

uucaacccga aauacgacug caaaaucaug accagcaaaa cugacgucuc cucguccguc     1200

aucaccucac ucggcgcaau cgugagcugc uacggcaaaa ccaaaugcac cgccuccaac     1260

aaaaacaaag gcaucauaaa aacauucagc aacggcugcg acuacgucuc gaacaaagga     1320

gucgacaccg uaucaguggg caacacccua uacuacguaa acaagcaaga aggcaaauca     1380

cucuacguaa aaggcgaacc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ucaagucaac gagaaaauca accaaucccu ugccuucaua     1500

cguaaaagcg acgaacuccu ucacaacgua aacgccggga aauccaccac uaacauaaug     1560

aucaccacca ucaucaucgu uaucauaguc auccuccucu cucucauagc agucggccua     1620

cuccuguacu gcaaagcgcg cuaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7492
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7492
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7493
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7493
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7494
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7494
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7495
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7495
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7496
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7496
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7497
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7497
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcugag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7498
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7498
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ucaaagcaaa cgcaauuaca accauacuaa ccgcugucac cuuuuguuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa caugcuccgc aguaucuaaa      300

ggauaccuca gcgcguuaag aacaggaugg uacacaucgg uaauaaccau cgaauuaucc      360

aacauaaaag aaaauaaaug caauggaaca gacgcaaaag ucaaauuaau uaaacaagaa      420

cuagacaaau auaaaaacgc aguaaccgaa uuacaaaugc uaauguguuc aacaccagca      480

acaggaucag gaucagcuau agcuucagga guugccguau gcaaagugcu acacuuagaa      540

ggagaaguga auaaaauaaa aucagcucua uuaucaacga acaaagccgu aguaucucua      600

ucaaauggcg uaucaguacu cacauucaaa guacucgacc uaaaaaacua uauagauaaa      660

caacuauuac ccauccuaaa uaaacaaagc ugcucuauau caaacaucga aacaguaaug      720

gaauuucaac aaaaaaacaa cagacuacua gaaauaaccc gagaguucuc aguuaaugca      780

ggaguaacaa caccagucuc aacauacaug cucacaaacu cagaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacucaugu cuaacaacgu ccaaauagua      900

agacaacaau ccuacagcau aauguguaua auaaaagaag aaguuuuagc auacgucgua      960

caacuacccu uauauggcgu aauagauaca ccaugcugga aacuccauac cucaccucua     1020

uguacaacaa auaccaaaga agguucuaau auaugccuaa cacgaacuga ccgaggaugg     1080

uacugugaca acgcaggauc agucucuuuc uuuccacaag cagaaaccug caaaguaugc     1140

aguaaccgcg uauuuugcga cacaaugaac ucccuaaccu uaccaucaga aguaaacuua     1200

uguaacguag acauauucaa uccaaaauau gacugcaaaa uaaugacauc aaaaacagac     1260

guaagcucau caguaauaac uucacuaggc gcaauuguau caugcuaugg aaaaaccaaa     1320

uguaccgcau ccaacaaaaa uaaaggaaua auaaaaaccu ucucuaacgg augcgacuac     1380

guaucaaaca aagguguaga uacaguuucu guaggaaaca cacucuacua uguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaagga gaaccaauaa uaaacuucua ugacccacuu     1500

guauuuccau cugaugaauu ugaugcaagc auaucacaag uaaacgaaaa aauaaaccaa     1560

ucucuagccu uuauacgaaa aagcgacgaa uuacuacaua acgucaacgc uggaaaauca     1620

acaacaaaca uaaugauaac aacaauaaua auaguaauaa uagucauccu auuaucacua     1680

aucgccguag gacuacuccu auacugcaaa gcuagauaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7499
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7499
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acuauccuca cagcagucac uuucugcuuc      240

gccucaggac aaaacauaac cgaagaguuc uaccaaucca caugcuccgc cgucuccaaa      300

ggcuaccucu cagcgcuccg caccggcugg uacacauccg ucaucaccau cgaacuaagc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaaag uuaaacucau caagcaagaa      420

cucgacaaau acaaaaacgc agucacagaa cuucaaaugc ucaugugcuc cacacccgcc      480

acagguucug gcucagcaau cgcaagcggc gucgccguau gcaaaguccu ucaccucgaa      540

ggcgaaguca acaaaaucaa auccgcccuc cucuccacca auaaagcugu cgucucacuc      600

uccaacggcg ucagcguccu cacauucaaa guccucgacc ucaaaaacua cauagacaag      660

caacuccucc cgauacucaa caaacaaagc ugcucuaucu ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ucgucuccuc gaaaucaccc gcgaguucuc aguaaacgcc      780

ggggucacca caccagucuc caccuacaug cucaccaacu ccgaacuccu uagccucaua      840

aacgacaugc ccauaaccaa cgaccaaaag aaacucauga gcaacaacgu acaaauaguc      900

cgacaacaau ccuauuccau cauguguauc aucaaagaag aaguccucgc auacguaguc      960

caacuccccc uauacggcgu aaucgacacc ccauguugga aacuccacac cucaccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuca cccgcacaga ccgcggcugg     1080

uacugcgaca acgcgggcuc cgucagcuuc uuuccccaag cggaaaccug caaagucugc     1140

agcaacagag ucuucugcga cacuaugaac ucccucaccc uccccucaga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa ucaugaccag caaaacugac     1260

gucuccucgu ccgucaucac cucacucggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaacau ucagcaacgg cugcgacuac     1380

gucucgaaca aaggagucga caccguauca gugggcaaca cccuauacua cguaaacaag     1440

caagaaggca aaucacucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucucaag ucaacgagaa aaucaaccaa     1560

ucccuugccu ucauacguaa aagcgacgaa cuccuucaca acguaaacgc cgggaaaucc     1620

accacuaaca uaaugaucac caccaucauc aucguuauca uagucauccu ccucucucuc     1680

auagcagucg gccuacuccu guacugcaaa gcgcgcuaag gacuaguaau aaggaaacug     1740

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1800

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7500
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7500
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7501
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7501
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7502
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7502
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7503
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7503
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7504
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7504
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7505
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7505
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcugag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7506
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7506
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ucaaagcaaa cgcaauuaca accauacuaa ccgcugucac cuuuuguuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa caugcuccgc aguaucuaaa      300

ggauaccuca gcgcguuaag aacaggaugg uacacaucgg uaauaaccau cgaauuaucc      360

aacauaaaag aaaauaaaug caauggaaca gacgcaaaag ucaaauuaau uaaacaagaa      420

cuagacaaau auaaaaacgc aguaaccgaa uuacaaaugc uaauguguuc aacaccagca      480

acaggaucag gaucagcuau agcuucagga guugccguau gcaaagugcu acacuuagaa      540

ggagaaguga auaaaauaaa aucagcucua uuaucaacga acaaagccgu aguaucucua      600

ucaaauggcg uaucaguacu cacauucaaa guacucgacc uaaaaaacua uauagauaaa      660

caacuauuac ccauccuaaa uaaacaaagc ugcucuauau caaacaucga aacaguaaug      720

gaauuucaac aaaaaaacaa cagacuacua gaaauaaccc gagaguucuc aguuaaugca      780

ggaguaacaa caccagucuc aacauacaug cucacaaacu cagaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacucaugu cuaacaacgu ccaaauagua      900

agacaacaau ccuacagcau aauguguaua auaaaagaag aaguuuuagc auacgucgua      960

caacuacccu uauauggcgu aauagauaca ccaugcugga aacuccauac cucaccucua     1020

uguacaacaa auaccaaaga agguucuaau auaugccuaa cacgaacuga ccgaggaugg     1080

uacugugaca acgcaggauc agucucuuuc uuuccacaag cagaaaccug caaaguaugc     1140

aguaaccgcg uauuuugcga cacaaugaac ucccuaaccu uaccaucaga aguaaacuua     1200

uguaacguag acauauucaa uccaaaauau gacugcaaaa uaaugacauc aaaaacagac     1260

guaagcucau caguaauaac uucacuaggc gcaauuguau caugcuaugg aaaaaccaaa     1320

uguaccgcau ccaacaaaaa uaaaggaaua auaaaaaccu ucucuaacgg augcgacuac     1380

guaucaaaca aagguguaga uacaguuucu guaggaaaca cacucuacua uguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaagga gaaccaauaa uaaacuucua ugacccacuu     1500

guauuuccau cugaugaauu ugaugcaagc auaucacaag uaaacgaaaa aauaaaccaa     1560

ucucuagccu uuauacgaaa aagcgacgaa uuacuacaua acgucaacgc uggaaaauca     1620

acaacaaaca uaaugauaac aacaauaaua auaguaauaa uagucauccu auuaucacua     1680

aucgccguag gacuacuccu auacugcaaa gcuagauaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7507
<211>  1998
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7507
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acuauccuca cagcagucac uuucugcuuc      240

gccucaggac aaaacauaac cgaagaguuc uaccaaucca caugcuccgc cgucuccaaa      300

ggcuaccucu cagcgcuccg caccggcugg uacacauccg ucaucaccau cgaacuaagc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaaag uuaaacucau caagcaagaa      420

cucgacaaau acaaaaacgc agucacagaa cuucaaaugc ucaugugcuc cacacccgcc      480

acagguucug gcucagcaau cgcaagcggc gucgccguau gcaaaguccu ucaccucgaa      540

ggcgaaguca acaaaaucaa auccgcccuc cucuccacca auaaagcugu cgucucacuc      600

uccaacggcg ucagcguccu cacauucaaa guccucgacc ucaaaaacua cauagacaag      660

caacuccucc cgauacucaa caaacaaagc ugcucuaucu ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ucgucuccuc gaaaucaccc gcgaguucuc aguaaacgcc      780

ggggucacca caccagucuc caccuacaug cucaccaacu ccgaacuccu uagccucaua      840

aacgacaugc ccauaaccaa cgaccaaaag aaacucauga gcaacaacgu acaaauaguc      900

cgacaacaau ccuauuccau cauguguauc aucaaagaag aaguccucgc auacguaguc      960

caacuccccc uauacggcgu aaucgacacc ccauguugga aacuccacac cucaccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuca cccgcacaga ccgcggcugg     1080

uacugcgaca acgcgggcuc cgucagcuuc uuuccccaag cggaaaccug caaagucugc     1140

agcaacagag ucuucugcga cacuaugaac ucccucaccc uccccucaga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa ucaugaccag caaaacugac     1260

gucuccucgu ccgucaucac cucacucggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaacau ucagcaacgg cugcgacuac     1380

gucucgaaca aaggagucga caccguauca gugggcaaca cccuauacua cguaaacaag     1440

caagaaggca aaucacucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucucaag ucaacgagaa aaucaaccaa     1560

ucccuugccu ucauacguaa aagcgacgaa cuccuucaca acguaaacgc cgggaaaucc     1620

accacuaaca uaaugaucac caccaucauc aucguuauca uagucauccu ccucucucuc     1680

auagcagucg gccuacuccu guacugcaaa gcgcgcuaag gacuaguacu ggcugcaucu     1740

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1800

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1860

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1980

uucagagcca ccagaauu                                                   1998


<210>  7508
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7508
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ugaugugcuc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccaacggcg ucagcgugcu gaccuucaag gugcuggacc ucaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcuccauca gcaacaucga gacggugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucag cgugaacgcc      780

ggggucacca cccccguguc cacguacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc cgaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc guacgugguc      960

cagcugcccc ucuacggcgu gaucgacacc cccugcugga agcugcacac gagcccccug     1020

ugcaccacca acaccaagga gggguccaac aucugccuca cgcgcaccga ccggggcugg     1080

uacugcgaca acgccggcag cgucuccuuc uucccgcagg ccgagaccug caaggugugc     1140

agcaaccgcg uguucugcga caccaugaac ucccugacgc ugcccagcga gguaaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gugagcucca gcgugaucac cucccugggg gccaucguca gcugcuacgg caagacgaag     1320

ugcaccgcca gcaacaagaa caaggggauc aucaagaccu ucuccaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugucc gucgggaaca cccuguacua cgugaacaag     1440

caggagggca agagccucua cgugaagggg gagcccauca ucaacuucua cgacccgcug     1500

gucuuccccu ccgacgaguu cgacgcgagc aucucccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucauccgcaa guccgacgag cugcuccaca acgugaacgc cggcaagagc     1620

acgaccaaca ucaugaucac caccaucauc aucgucauca ucgugauccu gcugucccuc     1680

aucgccgugg ggcugcugcu cuacugcaag gcccggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7509
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7509
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccuca gcgcccugcg caccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggag cugcagaugc ucaugugcuc cacccccgcc      480

accggcagcg gguccgccau cgccagcggc guggcggugu gcaagguccu gcaccuggag      540

ggcgagguga acaagaucaa guccgcccuc cugagcacca acaaggccgu ggucucccug      600

agcaacgggg uguccgugcu cacguucaag guccuggacc ugaagaacua caucgacaag      660

cagcuccugc cgauccugaa caagcagagc ugcuccauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa ccggcuccug gagaucaccc gcgaguucuc cgugaacgcc      780

ggcgucacca cgcccgugag caccuacaug cugaccaaca gcgagcuccu gucccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucauga gcaacaacgu gcagaucguc      900

cggcagcagu ccuacagcau caugugcauc aucaaggagg aggugcuggc cuacgugguc      960

cagcugcccc ucuacggggu gaucgacacg ccgugcugga agcugcacac cagcccccug     1020

ugcaccacca acacgaagga gggcagcaac aucugccuca cccgcaccga ccgggggugg     1080

uacugcgaca acgcgggcuc cgugagcuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg uguucugcga cacgaugaac agccugaccc ugcccuccga ggucaaccuc     1200

ugcaacgugg acaucuucaa cccgaaguac gacugcaaga ucaugaccag caagaccgac     1260

guguccagcu ccgucaucac gagccugggc gccaucgugu ccugcuacgg gaagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucuccaacgg gugcgacuac     1380

gugagcaaca agggcgucga cacggugagc gugggcaaca cccuguacua cgucaacaag     1440

caggagggga agucccucua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccucc aucagccagg ucaacgagaa gaucaaccag     1560

ucccuggcgu ucauccggaa guccgacgag cuccugcaca acgugaacgc cgggaagucc     1620

accaccaaca ucaugaucac cacgaucauc aucgugauca ucgucauccu gcucagccug     1680

aucgccgugg gccugcuccu guacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7510
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7510
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucu ccgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgag cuccagaugc ucaugugcuc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccaacggcg ucuccguccu caccuucaag guccucgacc ucaagaacua caucgacaag      660

cagcuccucc ccauccucaa caagcagucc ugcuccaucu ccaacaucga gaccgucaug      720

gaguuccagc agaagaacaa ccgccuccuc gagaucaccc gcgaguucuc cgucaacgcc      780

ggcgucacca cccccgucuc caccuacaug cucaccaacu ccgagcuccu cucccucauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcucaugu ccaacaacgu ccagaucguc      900

cgccagcagu ccuacuccau caugugcauc aucaaggagg agguccucgc cuacgucguc      960

cagcuccccc ucuacggcgu caucgacacc cccugcugga agcuccacac cuccccccuc     1020

ugcaccacca acaccaagga gggcuccaac aucugccuca cccgcaccga ccgcggcugg     1080

uacugcgaca acgccggcuc cgucuccuuc uucccccagg ccgagaccug caaggucugc     1140

uccaaccgcg ucuucugcga caccaugaac ucccucaccc uccccuccga ggucaaccuc     1200

ugcaacgucg acaucuucaa ccccaaguac gacugcaaga ucaugaccuc caagaccgac     1260

gucuccuccu ccgucaucac cucccucggc gccaucgucu ccugcuacgg caagaccaag     1320

ugcaccgccu ccaacaagaa caagggcauc aucaagaccu ucuccaacgg cugcgacuac     1380

gucuccaaca agggcgucga caccgucucc gucggcaaca cccucuacua cgucaacaag     1440

caggagggca agucccucua cgucaagggc gagcccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucccagg ucaacgagaa gaucaaccag     1560

ucccucgccu ucauccgcaa guccgacgag cuccuccaca acgucaacgc cggcaagucc     1620

accaccaaca ucaugaucac caccaucauc aucgucauca ucgucauccu ccucucccuc     1680

aucgccgucg gccuccuccu cuacugcaag gcccgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7511
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7511
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuuga gugcuuuaag aacuggaugg uacaccagcg uuauuacaau cgaacugucc      360

aacauuaagg agaauaaaug caacgguacc gacgccaagg ugaaacuaau caagcaggaa      420

cucgauaagu auaaaaaugc aguaacugag cugcagaugc uuauguguuc uacacccgcc      480

accggcucgg ggucagcuau agcaagcgga guggccgucu gcaaggugcu gcacuuggag      540

ggcgaaguua acaaaaucaa gagugcucuc cuguccacga auaaagccgu ggucucucug      600

agcaacggug uguccguacu cacuuuuaag guuuuagacc ugaagaauua cauugauaaa      660

cagcuuuugc cuauccugaa caagcaauca uguaguauua gcaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa uaggcuacuc gaaauaacac gggaguuuuc ugucaacgcg      780

ggggugacua ccccaguguc cacauauaug cugaccaauu cagaacuucu gagcuugauu      840

aacgacaugc cgaucacgaa cgaucagaag aaacucauga guaauaacgu ccaaauuguu      900

cgccagcagu cuuacuccau caugugcauc auuaaggagg aagugcuggc auauguagug      960

caguuacccc uguacggagu cauagacacu ccuuguugga aacuccauac aagcccacuu     1020

ugcaccacua auacaaagga gggcucgaac aucugucuga cccgaacgga ucguggcugg     1080

uacugcgaca augccggguc uguguccuuc uuuccccaag cugaaaccug uaagguuugc     1140

ucaaacagag uguucugcga uacaaugaau aguuugacuc uaccuagcga ggucaaccug     1200

uguaaugugg acauuuuuaa cccaaaauau gauugcaaga ucaugaccuc caaaacagac     1260

guaucuagcu caguuauaac uagccucgga gccauugugu ccuguuacgg uaagaccaaa     1320

ugcacagcaa gcaauaagaa caagggcauc aucaaaaccu ucucuaaugg gugugauuau     1380

gucucaaaca agggagugga cacugucagu gugggcaaua cgcuguacua uguuaacaaa     1440

caggagggua agagccuuua cgugaaaggg gaacccauua ucaacuuuua ugacccucug     1500

guauucccau ccgaugaguu ugacgcuucu auuucgcagg ucaaugaaaa gauaaaccaa     1560

aguuuggccu ucaucaggaa guccgaugag cuccugcaca augugaacgc gggaaaauca     1620

acaaccaaua uuaugaucac uaccaucauu auaguuauca uugugaucuu acugagucua     1680

auugccgucg gccuccugcu uuacugcaag gcacggugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7512
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7512
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccuga gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaacaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgag cugcagaugc ugaugugcag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcaacggcg ugagcgugcu gaccuucaag gugcuggacc ugaagaacua caucgacaag      660

cagcugcugc ccauccugaa caagcagagc ugcagcauca gcaacaucga gaccgugaug      720

gaguuccagc agaagaacaa cagacugcug gagaucacca gagaguucag cgugaacgcc      780

ggcgugacca cccccgugag caccuacaug cugaccaaca gcgagcugcu gagccugauc      840

aacgacaugc ccaucaccaa cgaccagaag aagcugauga gcaacaacgu gcagaucgug      900

agacagcaga gcuacagcau caugugcauc aucaaggagg aggugcuggc cuacguggug      960

cagcugcccc uguacggcgu gaucgacacc cccugcugga agcugcacac cagcccccug     1020

ugcaccacca acaccaagga gggcagcaac aucugccuga ccagaaccga cagaggcugg     1080

uacugcgaca acgccggcag cgugagcuuc uucccccagg ccgagaccug caaggugugc     1140

agcaacagag uguucugcga caccaugaac agccugaccc ugcccagcga ggugaaccug     1200

ugcaacgugg acaucuucaa ccccaaguac gacugcaaga ucaugaccag caagaccgac     1260

gugagcagca gcgugaucac cagccugggc gccaucguga gcugcuacgg caagaccaag     1320

ugcaccgcca gcaacaagaa caagggcauc aucaagaccu ucagcaacgg cugcgacuac     1380

gugagcaaca agggcgugga caccgugagc gugggcaaca cccuguacua cgugaacaag     1440

caggagggca agagccugua cgugaagggc gagcccauca ucaacuucua cgacccccug     1500

guguucccca gcgacgaguu cgacgccagc aucagccagg ugaacgagaa gaucaaccag     1560

agccuggccu ucaucagaaa gagcgacgag cugcugcaca acgugaacgc cggcaagagc     1620

accaccaaca ucaugaucac caccaucauc aucgugauca ucgugauccu gcugagccug     1680

aucgccgugg gccugcugcu guacugcaag gccagaugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7513
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7513
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugu ccgcccucag aacaggaugg uacaccucug uuaucacaau ugaacugagc      360

aacaucaagg agaauaaaug caacggcacc gacgccaagg ugaaacuuau caagcaggaa      420

cuggauaagu auaaaaaugc ugugacggag cuccagaugc ugauguguuc cacccccgcc      480

acagggucug gaagcgcuau ugccuccggc gucgcggugu gcaagguucu gcaccucgag      540

ggggaaguga acaaaaucaa gagcgcccug cuuucuacca auaaagcugu cgugucccug      600

agcaacggag uuucugugcu cacauuuaag guccuggacc uuaagaauua cauugauaaa      660

cagcugcucc cuauccugaa caagcaaucc uguagcauuu cuaauaucga gaccgugaug      720

gaguuccagc agaaaaacaa ucggcugcuc gaaauuacgc gcgaguuuuc cgugaacgcc      780

ggcgucacaa ccccgguuag cacauauaug cugaccaauu ccgaacuucu gucucucauc      840

aacgacaugc ccaucaccaa cgaucagaag aaacugauga gcaauaacgu gcaaauugug      900

agacagcagu ccuacagcau caugugcauu aucaaggagg aaguccuugc uuaugugguu      960

cagcugccuc ucuacggcgu gauugacaca cccuguugga aacugcauac gucuccucug     1020

ugcaccacaa auaccaagga gggguccaac aucugucuca cacggaccga ucgcggaugg     1080

uacugcgaca augccggcag cgucucuuuc uuuccccaag cggaaacgug uaaggugugc     1140

agcaacagag uuuucugcga uacaaugaac ucccugaccc uuccuucuga ggugaaucug     1200

uguaaugucg acaucuuuaa cccgaaauau gauugcaaga uuaugaccag caaaacagac     1260

guguccagcu cugucaucac cucccucggg gccauuguga gcuguuacgg aaagacaaaa     1320

ugcacggcuu cuaauaagaa caagggcauc auuaaaaccu ucuccaaugg gugugauuau     1380

guuagcaaca agggagugga cacagucucc gugggcaaua cccuguacua uguuaacaaa     1440

caggagggca agucucuuua cgugaaaggg gaacccauca ucaacuuuua ugacccucug     1500

gucuucccca gcgaugaguu ugacgccucc auuucucagg ugaaugaaaa gaucaaccaa     1560

agccucgcuu ucauucggaa guccgaugag cugcugcaca augugaacgc cggaaaaagc     1620

acaaccaaua ucaugauuac gaccaucauu aucguuauca uugucauccu ccugucucuu     1680

auugccgugg gccugcuccu guacugcaag gcucgcugag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7514
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7514
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

uuacuaaucc ucaaagcaaa cgcaauuaca accauacuaa ccgcugucac cuuuuguuuu      240

gccucaggac aaaacauaac ugaagaauuu uaccaaucaa caugcuccgc aguaucuaaa      300

ggauaccuca gcgcguuaag aacaggaugg uacacaucgg uaauaaccau cgaauuaucc      360

aacauaaaag aaaauaaaug caauggaaca gacgcaaaag ucaaauuaau uaaacaagaa      420

cuagacaaau auaaaaacgc aguaaccgaa uuacaaaugc uaauguguuc aacaccagca      480

acaggaucag gaucagcuau agcuucagga guugccguau gcaaagugcu acacuuagaa      540

ggagaaguga auaaaauaaa aucagcucua uuaucaacga acaaagccgu aguaucucua      600

ucaaauggcg uaucaguacu cacauucaaa guacucgacc uaaaaaacua uauagauaaa      660

caacuauuac ccauccuaaa uaaacaaagc ugcucuauau caaacaucga aacaguaaug      720

gaauuucaac aaaaaaacaa cagacuacua gaaauaaccc gagaguucuc aguuaaugca      780

ggaguaacaa caccagucuc aacauacaug cucacaaacu cagaacuccu aucacuaaua      840

aaugacaugc caauaacaaa cgaccaaaaa aaacucaugu cuaacaacgu ccaaauagua      900

agacaacaau ccuacagcau aauguguaua auaaaagaag aaguuuuagc auacgucgua      960

caacuacccu uauauggcgu aauagauaca ccaugcugga aacuccauac cucaccucua     1020

uguacaacaa auaccaaaga agguucuaau auaugccuaa cacgaacuga ccgaggaugg     1080

uacugugaca acgcaggauc agucucuuuc uuuccacaag cagaaaccug caaaguaugc     1140

aguaaccgcg uauuuugcga cacaaugaac ucccuaaccu uaccaucaga aguaaacuua     1200

uguaacguag acauauucaa uccaaaauau gacugcaaaa uaaugacauc aaaaacagac     1260

guaagcucau caguaauaac uucacuaggc gcaauuguau caugcuaugg aaaaaccaaa     1320

uguaccgcau ccaacaaaaa uaaaggaaua auaaaaaccu ucucuaacgg augcgacuac     1380

guaucaaaca aagguguaga uacaguuucu guaggaaaca cacucuacua uguaaauaaa     1440

caagaaggaa aaucacuaua cguaaaagga gaaccaauaa uaaacuucua ugacccacuu     1500

guauuuccau cugaugaauu ugaugcaagc auaucacaag uaaacgaaaa aauaaaccaa     1560

ucucuagccu uuauacgaaa aagcgacgaa uuacuacaua acgucaacgc uggaaaauca     1620

acaacaaaca uaaugauaac aacaauaaua auaguaauaa uagucauccu auuaucacua     1680

aucgccguag gacuacuccu auacugcaaa gcuagauaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7515
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7515
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccauaacc acuauccuca cagcagucac uuucugcuuc      240

gccucaggac aaaacauaac cgaagaguuc uaccaaucca caugcuccgc cgucuccaaa      300

ggcuaccucu cagcgcuccg caccggcugg uacacauccg ucaucaccau cgaacuaagc      360

aacauaaaag aaaacaaaug caacggcacc gacgccaaag uuaaacucau caagcaagaa      420

cucgacaaau acaaaaacgc agucacagaa cuucaaaugc ucaugugcuc cacacccgcc      480

acagguucug gcucagcaau cgcaagcggc gucgccguau gcaaaguccu ucaccucgaa      540

ggcgaaguca acaaaaucaa auccgcccuc cucuccacca auaaagcugu cgucucacuc      600

uccaacggcg ucagcguccu cacauucaaa guccucgacc ucaaaaacua cauagacaag      660

caacuccucc cgauacucaa caaacaaagc ugcucuaucu ccaacaucga aaccgucaug      720

gaguuccaac agaaaaacaa ucgucuccuc gaaaucaccc gcgaguucuc aguaaacgcc      780

ggggucacca caccagucuc caccuacaug cucaccaacu ccgaacuccu uagccucaua      840

aacgacaugc ccauaaccaa cgaccaaaag aaacucauga gcaacaacgu acaaauaguc      900

cgacaacaau ccuauuccau cauguguauc aucaaagaag aaguccucgc auacguaguc      960

caacuccccc uauacggcgu aaucgacacc ccauguugga aacuccacac cucaccacuc     1020

uguaccacca acaccaaaga aggcucaaac aucugccuca cccgcacaga ccgcggcugg     1080

uacugcgaca acgcgggcuc cgucagcuuc uuuccccaag cggaaaccug caaagucugc     1140

agcaacagag ucuucugcga cacuaugaac ucccucaccc uccccucaga agucaaccuc     1200

ugcaacgucg acaucuucaa cccgaaauac gacugcaaaa ucaugaccag caaaacugac     1260

gucuccucgu ccgucaucac cucacucggc gcaaucguga gcugcuacgg caaaaccaaa     1320

ugcaccgccu ccaacaaaaa caaaggcauc auaaaaacau ucagcaacgg cugcgacuac     1380

gucucgaaca aaggagucga caccguauca gugggcaaca cccuauacua cguaaacaag     1440

caagaaggca aaucacucua cguaaaaggc gaacccauca ucaacuucua cgacccccuc     1500

gucuuccccu ccgacgaguu cgacgccucc aucucucaag ucaacgagaa aaucaaccaa     1560

ucccuugccu ucauacguaa aagcgacgaa cuccuucaca acguaaacgc cgggaaaucc     1620

accacuaaca uaaugaucac caccaucauc aucguuauca uagucauccu ccucucucuc     1680

auagcagucg gccuacuccu guacugcaaa gcgcgcuaag gacuaguguc caccuguccc     1740

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7516
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7516
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcugaugug cuccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccaacg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcucca ucagcaacau cgagacggug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      660

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      840

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc      900

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc      960

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1020

ugcagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1200

aagugcaccg ccagcaacaa gaacaagggg aucaucaaga ccuucuccaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1380

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1440

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1500

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1560

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7517
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7517
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucagcgcccu gcgcaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gagcugcaga ugcucaugug cuccaccccc      360

gccaccggca gcggguccgc caucgccagc ggcguggcgg ugugcaaggu ccugcaccug      420

gagggcgagg ugaacaagau caaguccgcc cuccugagca ccaacaaggc cguggucucc      480

cugagcaacg ggguguccgu gcucacguuc aagguccugg accugaagaa cuacaucgac      540

aagcagcucc ugccgauccu gaacaagcag agcugcucca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cuccgugaac      660

gccggcguca ccacgcccgu gagcaccuac augcugacca acagcgagcu ccugucccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      780

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

guccagcugc cccucuacgg ggugaucgac acgccgugcu ggaagcugca caccagcccc      900

cugugcacca ccaacacgaa ggagggcagc aacaucugcc ucacccgcac cgaccggggg      960

ugguacugcg acaacgcggg cuccgugagc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcguguucug cgacacgaug aacagccuga cccugcccuc cgaggucaac     1080

cucugcaacg uggacaucuu caacccgaag uacgacugca agaucaugac cagcaagacc     1140

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucuccaa cgggugcgac     1260

uacgugagca acaagggcgu cgacacggug agcgugggca acacccugua cuacgucaac     1320

aagcaggagg ggaagucccu cuacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1440

cagucccugg cguucauccg gaaguccgac gagcuccugc acaacgugaa cgccgggaag     1500

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccugcucagc     1560

cugaucgccg ugggccugcu ccuguacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7518
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7518
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucuccgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaacaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gagcuccaga ugcucaugug cuccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccaacg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      540

aagcagcucc uccccauccu caacaagcag uccugcucca ucuccaacau cgagaccguc      600

auggaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      660

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      720

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      780

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      840

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc      900

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc      960

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1020

ugcuccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1080

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1140

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1200

aagugcaccg ccuccaacaa gaacaagggc aucaucaaga ccuucuccaa cggcugcgac     1260

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1320

aagcaggagg gcaagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1440

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1500

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1560

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7519
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7519
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugagugcuuu aagaacugga ugguacacca gcguuauuac aaucgaacug      240

uccaacauua aggagaauaa augcaacggu accgacgcca aggugaaacu aaucaagcag      300

gaacucgaua aguauaaaaa ugcaguaacu gagcugcaga ugcuuaugug uucuacaccc      360

gccaccggcu cggggucagc uauagcaagc ggaguggccg ucugcaaggu gcugcacuug      420

gagggcgaag uuaacaaaau caagagugcu cuccugucca cgaauaaagc cguggucucu      480

cugagcaacg guguguccgu acucacuuuu aagguuuuag accugaagaa uuacauugau      540

aaacagcuuu ugccuauccu gaacaagcaa ucauguagua uuagcaauau cgagaccgug      600

auggaguucc agcagaaaaa caauaggcua cucgaaauaa cacgggaguu uucugucaac      660

gcggggguga cuaccccagu guccacauau augcugacca auucagaacu ucugagcuug      720

auuaacgaca ugccgaucac gaacgaucag aagaaacuca ugaguaauaa cguccaaauu      780

guucgccagc agucuuacuc caucaugugc aucauuaagg aggaagugcu ggcauaugua      840

gugcaguuac cccuguacgg agucauagac acuccuuguu ggaaacucca uacaagccca      900

cuuugcacca cuaauacaaa ggagggcucg aacaucuguc ugacccgaac ggaucguggc      960

ugguacugcg acaaugccgg gucugugucc uucuuucccc aagcugaaac cuguaagguu     1020

ugcucaaaca gaguguucug cgauacaaug aauaguuuga cucuaccuag cgaggucaac     1080

cuguguaaug uggacauuuu uaacccaaaa uaugauugca agaucaugac cuccaaaaca     1140

gacguaucua gcucaguuau aacuagccuc ggagccauug uguccuguua cgguaagacc     1200

aaaugcacag caagcaauaa gaacaagggc aucaucaaaa ccuucucuaa ugggugugau     1260

uaugucucaa acaagggagu ggacacuguc agugugggca auacgcugua cuauguuaac     1320

aaacaggagg guaagagccu uuacgugaaa ggggaaccca uuaucaacuu uuaugacccu     1380

cugguauucc cauccgauga guuugacgcu ucuauuucgc aggucaauga aaagauaaac     1440

caaaguuugg ccuucaucag gaaguccgau gagcuccugc acaaugugaa cgcgggaaaa     1500

ucaacaacca auauuaugau cacuaccauc auuauaguua ucauugugau cuuacugagu     1560

cuaauugccg ucggccuccu gcuuuacugc aaggcacggu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7520
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7520
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugagcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaacaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gagcugcaga ugcugaugug cagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcaacg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      540

aagcagcugc ugcccauccu gaacaagcag agcugcagca ucagcaacau cgagaccgug      600

auggaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      660

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      720

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      780

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      840

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc      900

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc      960

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1020

ugcagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1080

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1140

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1200

aagugcaccg ccagcaacaa gaacaagggc aucaucaaga ccuucagcaa cggcugcgac     1260

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1320

aagcaggagg gcaagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1380

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1440

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1500

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1560

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7521
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7521
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc uguccgcccu cagaacagga ugguacaccu cuguuaucac aauugaacug      240

agcaacauca aggagaauaa augcaacggc accgacgcca aggugaaacu uaucaagcag      300

gaacuggaua aguauaaaaa ugcugugacg gagcuccaga ugcugaugug uuccaccccc      360

gccacagggu cuggaagcgc uauugccucc ggcgucgcgg ugugcaaggu ucugcaccuc      420

gagggggaag ugaacaaaau caagagcgcc cugcuuucua ccaauaaagc ugucgugucc      480

cugagcaacg gaguuucugu gcucacauuu aagguccugg accuuaagaa uuacauugau      540

aaacagcugc ucccuauccu gaacaagcaa uccuguagca uuucuaauau cgagaccgug      600

auggaguucc agcagaaaaa caaucggcug cucgaaauua cgcgcgaguu uuccgugaac      660

gccggcguca caaccccggu uagcacauau augcugacca auuccgaacu ucugucucuc      720

aucaacgaca ugcccaucac caacgaucag aagaaacuga ugagcaauaa cgugcaaauu      780

gugagacagc aguccuacag caucaugugc auuaucaagg aggaaguccu ugcuuaugug      840

guucagcugc cucucuacgg cgugauugac acacccuguu ggaaacugca uacgucuccu      900

cugugcacca caaauaccaa ggaggggucc aacaucuguc ucacacggac cgaucgcgga      960

ugguacugcg acaaugccgg cagcgucucu uucuuucccc aagcggaaac guguaaggug     1020

ugcagcaaca gaguuuucug cgauacaaug aacucccuga cccuuccuuc ugaggugaau     1080

cuguguaaug ucgacaucuu uaacccgaaa uaugauugca agauuaugac cagcaaaaca     1140

gacgugucca gcucugucau caccucccuc ggggccauug ugagcuguua cggaaagaca     1200

aaaugcacgg cuucuaauaa gaacaagggc aucauuaaaa ccuucuccaa ugggugugau     1260

uauguuagca acaagggagu ggacacaguc uccgugggca auacccugua cuauguuaac     1320

aaacaggagg gcaagucucu uuacgugaaa ggggaaccca ucaucaacuu uuaugacccu     1380

cuggucuucc ccagcgauga guuugacgcc uccauuucuc aggugaauga aaagaucaac     1440

caaagccucg cuuucauucg gaaguccgau gagcugcugc acaaugugaa cgccggaaaa     1500

agcacaacca auaucaugau uacgaccauc auuaucguua ucauugucau ccuccugucu     1560

cuuauugccg ugggccugcu ccuguacugc aaggcucgcu gaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7522
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7522
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaauuacuaa uccucaaagc aaacgcaauu acaaccauac uaaccgcugu caccuuuugu      120

uuugccucag gacaaaacau aacugaagaa uuuuaccaau caacaugcuc cgcaguaucu      180

aaaggauacc ucagcgcguu aagaacagga ugguacacau cgguaauaac caucgaauua      240

uccaacauaa aagaaaauaa augcaaugga acagacgcaa aagucaaauu aauuaaacaa      300

gaacuagaca aauauaaaaa cgcaguaacc gaauuacaaa ugcuaaugug uucaacacca      360

gcaacaggau caggaucagc uauagcuuca ggaguugccg uaugcaaagu gcuacacuua      420

gaaggagaag ugaauaaaau aaaaucagcu cuauuaucaa cgaacaaagc cguaguaucu      480

cuaucaaaug gcguaucagu acucacauuc aaaguacucg accuaaaaaa cuauauagau      540

aaacaacuau uacccauccu aaauaaacaa agcugcucua uaucaaacau cgaaacagua      600

auggaauuuc aacaaaaaaa caacagacua cuagaaauaa cccgagaguu cucaguuaau      660

gcaggaguaa caacaccagu cucaacauac augcucacaa acucagaacu ccuaucacua      720

auaaaugaca ugccaauaac aaacgaccaa aaaaaacuca ugucuaacaa cguccaaaua      780

guaagacaac aauccuacag cauaaugugu auaauaaaag aagaaguuuu agcauacguc      840

guacaacuac ccuuauaugg cguaauagau acaccaugcu ggaaacucca uaccucaccu      900

cuauguacaa caaauaccaa agaagguucu aauauaugcc uaacacgaac ugaccgagga      960

ugguacugug acaacgcagg aucagucucu uucuuuccac aagcagaaac cugcaaagua     1020

ugcaguaacc gcguauuuug cgacacaaug aacucccuaa ccuuaccauc agaaguaaac     1080

uuauguaacg uagacauauu caauccaaaa uaugacugca aaauaaugac aucaaaaaca     1140

gacguaagcu caucaguaau aacuucacua ggcgcaauug uaucaugcua uggaaaaacc     1200

aaauguaccg cauccaacaa aaauaaagga auaauaaaaa ccuucucuaa cggaugcgac     1260

uacguaucaa acaaaggugu agauacaguu ucuguaggaa acacacucua cuauguaaau     1320

aaacaagaag gaaaaucacu auacguaaaa ggagaaccaa uaauaaacuu cuaugaccca     1380

cuuguauuuc caucugauga auuugaugca agcauaucac aaguaaacga aaaaauaaac     1440

caaucucuag ccuuuauacg aaaaagcgac gaauuacuac auaacgucaa cgcuggaaaa     1500

ucaacaacaa acauaaugau aacaacaaua auaauaguaa uaauagucau ccuauuauca     1560

cuaaucgccg uaggacuacu ccuauacugc aaagcuagau aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7523
<211>  1931
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7523
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgccaua accacuaucc ucacagcagu cacuuucugc      120

uucgccucag gacaaaacau aaccgaagag uucuaccaau ccacaugcuc cgccgucucc      180

aaaggcuacc ucucagcgcu ccgcaccggc ugguacacau ccgucaucac caucgaacua      240

agcaacauaa aagaaaacaa augcaacggc accgacgcca aaguuaaacu caucaagcaa      300

gaacucgaca aauacaaaaa cgcagucaca gaacuucaaa ugcucaugug cuccacaccc      360

gccacagguu cuggcucagc aaucgcaagc ggcgucgccg uaugcaaagu ccuucaccuc      420

gaaggcgaag ucaacaaaau caaauccgcc cuccucucca ccaauaaagc ugucgucuca      480

cucuccaacg gcgucagcgu ccucacauuc aaaguccucg accucaaaaa cuacauagac      540

aagcaacucc ucccgauacu caacaaacaa agcugcucua ucuccaacau cgaaaccguc      600

auggaguucc aacagaaaaa caaucgucuc cucgaaauca cccgcgaguu cucaguaaac      660

gccgggguca ccacaccagu cuccaccuac augcucacca acuccgaacu ccuuagccuc      720

auaaacgaca ugcccauaac caacgaccaa aagaaacuca ugagcaacaa cguacaaaua      780

guccgacaac aauccuauuc caucaugugu aucaucaaag aagaaguccu cgcauacgua      840

guccaacucc cccuauacgg cguaaucgac accccauguu ggaaacucca caccucacca      900

cucuguacca ccaacaccaa agaaggcuca aacaucugcc ucacccgcac agaccgcggc      960

ugguacugcg acaacgcggg cuccgucagc uucuuucccc aagcggaaac cugcaaaguc     1020

ugcagcaaca gagucuucug cgacacuaug aacucccuca cccuccccuc agaagucaac     1080

cucugcaacg ucgacaucuu caacccgaaa uacgacugca aaaucaugac cagcaaaacu     1140

gacgucuccu cguccgucau caccucacuc ggcgcaaucg ugagcugcua cggcaaaacc     1200

aaaugcaccg ccuccaacaa aaacaaaggc aucauaaaaa cauucagcaa cggcugcgac     1260

uacgucucga acaaaggagu cgacaccgua ucagugggca acacccuaua cuacguaaac     1320

aagcaagaag gcaaaucacu cuacguaaaa ggcgaaccca ucaucaacuu cuacgacccc     1380

cucgucuucc ccuccgacga guucgacgcc uccaucucuc aagucaacga gaaaaucaac     1440

caaucccuug ccuucauacg uaaaagcgac gaacuccuuc acaacguaaa cgccgggaaa     1500

uccaccacua acauaaugau caccaccauc aucaucguua ucauagucau ccuccucucu     1560

cucauagcag ucggccuacu ccuguacugc aaagcgcgcu aaggacuagu gcaucacauu     1620

uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu     1680

caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc     1740

uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga     1800

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1920

ccaccagaau u                                                          1931


<210>  7524
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7524
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagaugcu gaugugcucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccaacggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcuccaucag caacaucgag acggugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc gugaacgccg      660

gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg uacguggucc      840

agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg agcccccugu      900

gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac cggggcuggu      960

acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc aaggugugca     1020

gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag guaaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc aagacgaagu     1200

gcaccgccag caacaagaac aaggggauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccucuac gugaaggggg agcccaucau caacuucuac gacccgcugg     1380

ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag aucaaccaga     1440

gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca     1500

cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug cugucccuca     1560

ucgccguggg gcugcugcuc uacugcaagg cccggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7525
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7525
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucag cgcccugcgc accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggagc ugcagaugcu caugugcucc acccccgcca      360

ccggcagcgg guccgccauc gccagcggcg uggcggugug caagguccug caccuggagg      420

gcgaggugaa caagaucaag uccgcccucc ugagcaccaa caaggccgug gucucccuga      480

gcaacggggu guccgugcuc acguucaagg uccuggaccu gaagaacuac aucgacaagc      540

agcuccugcc gauccugaac aagcagagcu gcuccaucag caacaucgag accgugaugg      600

aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucucc gugaacgccg      660

gcgucaccac gcccgugagc accuacaugc ugaccaacag cgagcuccug ucccugauca      720

acgacaugcc caucaccaac gaccagaaga agcucaugag caacaacgug cagaucgucc      780

ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggucc      840

agcugccccu cuacggggug aucgacacgc cgugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa cacgaaggag ggcagcaaca ucugccucac ccgcaccgac cggggguggu      960

acugcgacaa cgcgggcucc gugagcuucu ucccccaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu guucugcgac acgaugaaca gccugacccu gcccuccgag gucaaccucu     1080

gcaacgugga caucuucaac ccgaaguacg acugcaagau caugaccagc aagaccgacg     1140

uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg aagaccaagu     1200

gcaccgccag caacaagaac aagggcauca ucaagaccuu cuccaacggg ugcgacuacg     1260

ugagcaacaa gggcgucgac acggugagcg ugggcaacac ccuguacuac gucaacaagc     1320

aggaggggaa gucccucuac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccucca ucagccaggu caacgagaag aucaaccagu     1440

cccuggcguu cauccggaag uccgacgagc uccugcacaa cgugaacgcc gggaagucca     1500

ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccug cucagccuga     1560

ucgccguggg ccugcuccug uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7526
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7526
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucuc cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgagc uccagaugcu caugugcucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccaacggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac aucgacaagc      540

agcuccuccc cauccucaac aagcaguccu gcuccaucuc caacaucgag accgucaugg      600

aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc gucaacgccg      660

gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc ucccucauca      720

acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc cagaucgucc      780

gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc uacgucgucc      840

agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc uccccccucu      900

gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu      960

acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc aaggucugcu     1020

ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag gucaaccucu     1080

gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc aagaccgacg     1140

ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc aagaccaagu     1200

gcaccgccuc caacaagaac aagggcauca ucaagaccuu cuccaacggc ugcgacuacg     1260

ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac gucaacaagc     1320

aggagggcaa gucccucuac gucaagggcg agcccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag aucaaccagu     1440

cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc ggcaagucca     1500

ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc cucucccuca     1560

ucgccgucgg ccuccuccuc uacugcaagg cccgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7527
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7527
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuugag ugcuuuaaga acuggauggu acaccagcgu uauuacaauc gaacugucca      240

acauuaagga gaauaaaugc aacgguaccg acgccaaggu gaaacuaauc aagcaggaac      300

ucgauaagua uaaaaaugca guaacugagc ugcagaugcu uauguguucu acacccgcca      360

ccggcucggg gucagcuaua gcaagcggag uggccgucug caaggugcug cacuuggagg      420

gcgaaguuaa caaaaucaag agugcucucc uguccacgaa uaaagccgug gucucucuga      480

gcaacggugu guccguacuc acuuuuaagg uuuuagaccu gaagaauuac auugauaaac      540

agcuuuugcc uauccugaac aagcaaucau guaguauuag caauaucgag accgugaugg      600

aguuccagca gaaaaacaau aggcuacucg aaauaacacg ggaguuuucu gucaacgcgg      660

gggugacuac cccagugucc acauauaugc ugaccaauuc agaacuucug agcuugauua      720

acgacaugcc gaucacgaac gaucagaaga aacucaugag uaauaacguc caaauuguuc      780

gccagcaguc uuacuccauc augugcauca uuaaggagga agugcuggca uauguagugc      840

aguuaccccu guacggaguc auagacacuc cuuguuggaa acuccauaca agcccacuuu      900

gcaccacuaa uacaaaggag ggcucgaaca ucugucugac ccgaacggau cguggcuggu      960

acugcgacaa ugccgggucu guguccuucu uuccccaagc ugaaaccugu aagguuugcu     1020

caaacagagu guucugcgau acaaugaaua guuugacucu accuagcgag gucaaccugu     1080

guaaugugga cauuuuuaac ccaaaauaug auugcaagau caugaccucc aaaacagacg     1140

uaucuagcuc aguuauaacu agccucggag ccauuguguc cuguuacggu aagaccaaau     1200

gcacagcaag caauaagaac aagggcauca ucaaaaccuu cucuaauggg ugugauuaug     1260

ucucaaacaa gggaguggac acugucagug ugggcaauac gcuguacuau guuaacaaac     1320

aggaggguaa gagccuuuac gugaaagggg aacccauuau caacuuuuau gacccucugg     1380

uauucccauc cgaugaguuu gacgcuucua uuucgcaggu caaugaaaag auaaaccaaa     1440

guuuggccuu caucaggaag uccgaugagc uccugcacaa ugugaacgcg ggaaaaucaa     1500

caaccaauau uaugaucacu accaucauua uaguuaucau ugugaucuua cugagucuaa     1560

uugccgucgg ccuccugcuu uacugcaagg cacggugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7528
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7528
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccugag cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaacaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgagc ugcagaugcu gaugugcagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcaacggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac aucgacaagc      540

agcugcugcc cauccugaac aagcagagcu gcagcaucag caacaucgag accgugaugg      600

aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc gugaacgccg      660

gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug agccugauca      720

acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug cagaucguga      780

gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc uacguggugc      840

agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc agcccccugu      900

gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac agaggcuggu      960

acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc aaggugugca     1020

gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag gugaaccugu     1080

gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc aagaccgacg     1140

ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc aagaccaagu     1200

gcaccgccag caacaagaac aagggcauca ucaagaccuu cagcaacggc ugcgacuacg     1260

ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac gugaacaagc     1320

aggagggcaa gagccuguac gugaagggcg agcccaucau caacuucuac gacccccugg     1380

uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag aucaaccaga     1440

gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca     1500

ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug cugagccuga     1560

ucgccguggg ccugcugcug uacugcaagg ccagaugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7529
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7529
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuguc cgcccucaga acaggauggu acaccucugu uaucacaauu gaacugagca      240

acaucaagga gaauaaaugc aacggcaccg acgccaaggu gaaacuuauc aagcaggaac      300

uggauaagua uaaaaaugcu gugacggagc uccagaugcu gauguguucc acccccgcca      360

cagggucugg aagcgcuauu gccuccggcg ucgcggugug caagguucug caccucgagg      420

gggaagugaa caaaaucaag agcgcccugc uuucuaccaa uaaagcuguc gugucccuga      480

gcaacggagu uucugugcuc acauuuaagg uccuggaccu uaagaauuac auugauaaac      540

agcugcuccc uauccugaac aagcaauccu guagcauuuc uaauaucgag accgugaugg      600

aguuccagca gaaaaacaau cggcugcucg aaauuacgcg cgaguuuucc gugaacgccg      660

gcgucacaac cccgguuagc acauauaugc ugaccaauuc cgaacuucug ucucucauca      720

acgacaugcc caucaccaac gaucagaaga aacugaugag caauaacgug caaauuguga      780

gacagcaguc cuacagcauc augugcauua ucaaggagga aguccuugcu uaugugguuc      840

agcugccucu cuacggcgug auugacacac ccuguuggaa acugcauacg ucuccucugu      900

gcaccacaaa uaccaaggag ggguccaaca ucugucucac acggaccgau cgcggauggu      960

acugcgacaa ugccggcagc gucucuuucu uuccccaagc ggaaacgugu aaggugugca     1020

gcaacagagu uuucugcgau acaaugaacu cccugacccu uccuucugag gugaaucugu     1080

guaaugucga caucuuuaac ccgaaauaug auugcaagau uaugaccagc aaaacagacg     1140

uguccagcuc ugucaucacc ucccucgggg ccauugugag cuguuacgga aagacaaaau     1200

gcacggcuuc uaauaagaac aagggcauca uuaaaaccuu cuccaauggg ugugauuaug     1260

uuagcaacaa gggaguggac acagucuccg ugggcaauac ccuguacuau guuaacaaac     1320

aggagggcaa gucucuuuac gugaaagggg aacccaucau caacuuuuau gacccucugg     1380

ucuuccccag cgaugaguuu gacgccucca uuucucaggu gaaugaaaag aucaaccaaa     1440

gccucgcuuu cauucggaag uccgaugagc ugcugcacaa ugugaacgcc ggaaaaagca     1500

caaccaauau caugauuacg accaucauua ucguuaucau ugucauccuc cugucucuua     1560

uugccguggg ccugcuccug uacugcaagg cucgcugagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7530
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7530
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaau       60

uacuaauccu caaagcaaac gcaauuacaa ccauacuaac cgcugucacc uuuuguuuug      120

ccucaggaca aaacauaacu gaagaauuuu accaaucaac augcuccgca guaucuaaag      180

gauaccucag cgcguuaaga acaggauggu acacaucggu aauaaccauc gaauuaucca      240

acauaaaaga aaauaaaugc aauggaacag acgcaaaagu caaauuaauu aaacaagaac      300

uagacaaaua uaaaaacgca guaaccgaau uacaaaugcu aauguguuca acaccagcaa      360

caggaucagg aucagcuaua gcuucaggag uugccguaug caaagugcua cacuuagaag      420

gagaagugaa uaaaauaaaa ucagcucuau uaucaacgaa caaagccgua guaucucuau      480

caaauggcgu aucaguacuc acauucaaag uacucgaccu aaaaaacuau auagauaaac      540

aacuauuacc cauccuaaau aaacaaagcu gcucuauauc aaacaucgaa acaguaaugg      600

aauuucaaca aaaaaacaac agacuacuag aaauaacccg agaguucuca guuaaugcag      660

gaguaacaac accagucuca acauacaugc ucacaaacuc agaacuccua ucacuaauaa      720

augacaugcc aauaacaaac gaccaaaaaa aacucauguc uaacaacguc caaauaguaa      780

gacaacaauc cuacagcaua auguguauaa uaaaagaaga aguuuuagca uacgucguac      840

aacuacccuu auauggcgua auagauacac caugcuggaa acuccauacc ucaccucuau      900

guacaacaaa uaccaaagaa gguucuaaua uaugccuaac acgaacugac cgaggauggu      960

acugugacaa cgcaggauca gucucuuucu uuccacaagc agaaaccugc aaaguaugca     1020

guaaccgcgu auuuugcgac acaaugaacu cccuaaccuu accaucagaa guaaacuuau     1080

guaacguaga cauauucaau ccaaaauaug acugcaaaau aaugacauca aaaacagacg     1140

uaagcucauc aguaauaacu ucacuaggcg caauuguauc augcuaugga aaaaccaaau     1200

guaccgcauc caacaaaaau aaaggaauaa uaaaaaccuu cucuaacgga ugcgacuacg     1260

uaucaaacaa agguguagau acaguuucug uaggaaacac acucuacuau guaaauaaac     1320

aagaaggaaa aucacuauac guaaaaggag aaccaauaau aaacuucuau gacccacuug     1380

uauuuccauc ugaugaauuu gaugcaagca uaucacaagu aaacgaaaaa auaaaccaau     1440

cucuagccuu uauacgaaaa agcgacgaau uacuacauaa cgucaacgcu ggaaaaucaa     1500

caacaaacau aaugauaaca acaauaauaa uaguaauaau agucauccua uuaucacuaa     1560

ucgccguagg acuacuccua uacugcaaag cuagauaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7531
<211>  1927
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7531
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu caaagccaac gccauaacca cuauccucac agcagucacu uucugcuucg      120

ccucaggaca aaacauaacc gaagaguucu accaauccac augcuccgcc gucuccaaag      180

gcuaccucuc agcgcuccgc accggcuggu acacauccgu caucaccauc gaacuaagca      240

acauaaaaga aaacaaaugc aacggcaccg acgccaaagu uaaacucauc aagcaagaac      300

ucgacaaaua caaaaacgca gucacagaac uucaaaugcu caugugcucc acacccgcca      360

cagguucugg cucagcaauc gcaagcggcg ucgccguaug caaaguccuu caccucgaag      420

gcgaagucaa caaaaucaaa uccgcccucc ucuccaccaa uaaagcuguc gucucacucu      480

ccaacggcgu cagcguccuc acauucaaag uccucgaccu caaaaacuac auagacaagc      540

aacuccuccc gauacucaac aaacaaagcu gcucuaucuc caacaucgaa accgucaugg      600

aguuccaaca gaaaaacaau cgucuccucg aaaucacccg cgaguucuca guaaacgccg      660

gggucaccac accagucucc accuacaugc ucaccaacuc cgaacuccuu agccucauaa      720

acgacaugcc cauaaccaac gaccaaaaga aacucaugag caacaacgua caaauagucc      780

gacaacaauc cuauuccauc auguguauca ucaaagaaga aguccucgca uacguagucc      840

aacucccccu auacggcgua aucgacaccc cauguuggaa acuccacacc ucaccacucu      900

guaccaccaa caccaaagaa ggcucaaaca ucugccucac ccgcacagac cgcggcuggu      960

acugcgacaa cgcgggcucc gucagcuucu uuccccaagc ggaaaccugc aaagucugca     1020

gcaacagagu cuucugcgac acuaugaacu cccucacccu ccccucagaa gucaaccucu     1080

gcaacgucga caucuucaac ccgaaauacg acugcaaaau caugaccagc aaaacugacg     1140

ucuccucguc cgucaucacc ucacucggcg caaucgugag cugcuacggc aaaaccaaau     1200

gcaccgccuc caacaaaaac aaaggcauca uaaaaacauu cagcaacggc ugcgacuacg     1260

ucucgaacaa aggagucgac accguaucag ugggcaacac ccuauacuac guaaacaagc     1320

aagaaggcaa aucacucuac guaaaaggcg aacccaucau caacuucuac gacccccucg     1380

ucuuccccuc cgacgaguuc gacgccucca ucucucaagu caacgagaaa aucaaccaau     1440

cccuugccuu cauacguaaa agcgacgaac uccuucacaa cguaaacgcc gggaaaucca     1500

ccacuaacau aaugaucacc accaucauca ucguuaucau agucauccuc cucucucuca     1560

uagcagucgg ccuacuccug uacugcaaag cgcgcuaagg acuagugcau cacauuuaaa     1620

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1680

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1740

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1920

cagaauu                                                               1927


<210>  7532
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7532
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagaug      300

cugaugugcu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccaacggc gucagcgugc ugaccuucaa ggugcuggac      480

cucaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcuccauc      540

agcaacaucg agacggugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguuca gcgugaacgc cggggucacc acccccgugu ccacguacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug ccgaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg cguacguggu ccagcugccc cucuacggcg ugaucgacac ccccugcugg      840

aagcugcaca cgagcccccu gugcaccacc aacaccaagg agggguccaa caucugccuc      900

acgcgcaccg accggggcug guacugcgac aacgccggca gcgucuccuu cuucccgcag      960

gccgagaccu gcaaggugug cagcaaccgc guguucugcg acaccaugaa cucccugacg     1020

cugcccagcg agguaaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgugagcucc agcgugauca ccucccuggg ggccaucguc     1140

agcugcuacg gcaagacgaa gugcaccgcc agcaacaaga acaaggggau caucaagacc     1200

uucuccaacg gcugcgacua cgugagcaac aagggcgugg acaccguguc cgucgggaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccucu acgugaaggg ggagcccauc     1320

aucaacuucu acgacccgcu ggucuucccc uccgacgagu ucgacgcgag caucucccag     1380

gugaacgaga agaucaacca gagccuggcc uucauccgca aguccgacga gcugcuccac     1440

aacgugaacg ccggcaagag cacgaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgugaucc ugcugucccu caucgccgug gggcugcugc ucuacugcaa ggcccgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7533
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt1)

<400>  7533
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc agcgcccugc gcaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga gcugcagaug      300

cucaugugcu ccacccccgc caccggcagc ggguccgcca ucgccagcgg cguggcggug      360

ugcaaggucc ugcaccugga gggcgaggug aacaagauca aguccgcccu ccugagcacc      420

aacaaggccg uggucucccu gagcaacggg guguccgugc ucacguucaa gguccuggac      480

cugaagaacu acaucgacaa gcagcuccug ccgauccuga acaagcagag cugcuccauc      540

agcaacaucg agaccgugau ggaguuccag cagaagaaca accggcuccu ggagaucacc      600

cgcgaguucu ccgugaacgc cggcgucacc acgcccguga gcaccuacau gcugaccaac      660

agcgagcucc ugucccugau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

agcaacaacg ugcagaucgu ccggcagcag uccuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu ccagcugccc cucuacgggg ugaucgacac gccgugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacacgaagg agggcagcaa caucugccuc      900

acccgcaccg accgggggug guacugcgac aacgcgggcu ccgugagcuu cuucccccag      960

gccgagaccu gcaaggucug cuccaaccgc guguucugcg acacgaugaa cagccugacc     1020

cugcccuccg aggucaaccu cugcaacgug gacaucuuca acccgaagua cgacugcaag     1080

aucaugacca gcaagaccga cguguccagc uccgucauca cgagccuggg cgccaucgug     1140

uccugcuacg ggaagaccaa gugcaccgcc agcaacaaga acaagggcau caucaagacc     1200

uucuccaacg ggugcgacua cgugagcaac aagggcgucg acacggugag cgugggcaac     1260

acccuguacu acgucaacaa gcaggagggg aagucccucu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccuc caucagccag     1380

gucaacgaga agaucaacca gucccuggcg uucauccgga aguccgacga gcuccugcac     1440

aacgugaacg ccgggaaguc caccaccaac aucaugauca ccacgaucau caucgugauc     1500

aucgucaucc ugcucagccu gaucgccgug ggccugcucc uguacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7534
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt2)

<400>  7534
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc uccgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga gcuccagaug      300

cucaugugcu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccaacggc gucuccgucc ucaccuucaa gguccucgac      480

cucaagaacu acaucgacaa gcagcuccuc cccauccuca acaagcaguc cugcuccauc      540

uccaacaucg agaccgucau ggaguuccag cagaagaaca accgccuccu cgagaucacc      600

cgcgaguucu ccgucaacgc cggcgucacc acccccgucu ccaccuacau gcucaccaac      660

uccgagcucc ucucccucau caacgacaug cccaucacca acgaccagaa gaagcucaug      720

uccaacaacg uccagaucgu ccgccagcag uccuacucca ucaugugcau caucaaggag      780

gagguccucg ccuacgucgu ccagcucccc cucuacggcg ucaucgacac ccccugcugg      840

aagcuccaca ccuccccccu cugcaccacc aacaccaagg agggcuccaa caucugccuc      900

acccgcaccg accgcggcug guacugcgac aacgccggcu ccgucuccuu cuucccccag      960

gccgagaccu gcaaggucug cuccaaccgc gucuucugcg acaccaugaa cucccucacc     1020

cuccccuccg aggucaaccu cugcaacguc gacaucuuca accccaagua cgacugcaag     1080

aucaugaccu ccaagaccga cgucuccucc uccgucauca ccucccucgg cgccaucguc     1140

uccugcuacg gcaagaccaa gugcaccgcc uccaacaaga acaagggcau caucaagacc     1200

uucuccaacg gcugcgacua cgucuccaac aagggcgucg acaccgucuc cgucggcaac     1260

acccucuacu acgucaacaa gcaggagggc aagucccucu acgucaaggg cgagcccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucccag     1380

gucaacgaga agaucaacca gucccucgcc uucauccgca aguccgacga gcuccuccac     1440

aacgucaacg ccggcaaguc caccaccaac aucaugauca ccaccaucau caucgucauc     1500

aucgucaucc uccucucccu caucgccguc ggccuccucc ucuacugcaa ggcccgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7535
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt3)

<400>  7535
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug agugcuuuaa gaacuggaug guacaccagc      180

guuauuacaa ucgaacuguc caacauuaag gagaauaaau gcaacgguac cgacgccaag      240

gugaaacuaa ucaagcagga acucgauaag uauaaaaaug caguaacuga gcugcagaug      300

cuuauguguu cuacacccgc caccggcucg gggucagcua uagcaagcgg aguggccguc      360

ugcaaggugc ugcacuugga gggcgaaguu aacaaaauca agagugcucu ccuguccacg      420

aauaaagccg uggucucucu gagcaacggu guguccguac ucacuuuuaa gguuuuagac      480

cugaagaauu acauugauaa acagcuuuug ccuauccuga acaagcaauc auguaguauu      540

agcaauaucg agaccgugau ggaguuccag cagaaaaaca auaggcuacu cgaaauaaca      600

cgggaguuuu cugucaacgc gggggugacu accccagugu ccacauauau gcugaccaau      660

ucagaacuuc ugagcuugau uaacgacaug ccgaucacga acgaucagaa gaaacucaug      720

aguaauaacg uccaaauugu ucgccagcag ucuuacucca ucaugugcau cauuaaggag      780

gaagugcugg cauauguagu gcaguuaccc cuguacggag ucauagacac uccuuguugg      840

aaacuccaua caagcccacu uugcaccacu aauacaaagg agggcucgaa caucugucug      900

acccgaacgg aucguggcug guacugcgac aaugccgggu cuguguccuu cuuuccccaa      960

gcugaaaccu guaagguuug cucaaacaga guguucugcg auacaaugaa uaguuugacu     1020

cuaccuagcg aggucaaccu guguaaugug gacauuuuua acccaaaaua ugauugcaag     1080

aucaugaccu ccaaaacaga cguaucuagc ucaguuauaa cuagccucgg agccauugug     1140

uccuguuacg guaagaccaa augcacagca agcaauaaga acaagggcau caucaaaacc     1200

uucucuaaug ggugugauua ugucucaaac aagggagugg acacugucag ugugggcaau     1260

acgcuguacu auguuaacaa acaggagggu aagagccuuu acgugaaagg ggaacccauu     1320

aucaacuuuu augacccucu gguauuccca uccgaugagu uugacgcuuc uauuucgcag     1380

gucaaugaaa agauaaacca aaguuuggcc uucaucagga aguccgauga gcuccugcac     1440

aaugugaacg cgggaaaauc aacaaccaau auuaugauca cuaccaucau uauaguuauc     1500

auugugaucu uacugagucu aauugccguc ggccuccugc uuuacugcaa ggcacgguga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7536
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt4)

<400>  7536
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug agcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaacaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga gcugcagaug      300

cugaugugca gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcaacggc gugagcgugc ugaccuucaa ggugcuggac      480

cugaagaacu acaucgacaa gcagcugcug cccauccuga acaagcagag cugcagcauc      540

agcaacaucg agaccgugau ggaguuccag cagaagaaca acagacugcu ggagaucacc      600

agagaguuca gcgugaacgc cggcgugacc acccccguga gcaccuacau gcugaccaac      660

agcgagcugc ugagccugau caacgacaug cccaucacca acgaccagaa gaagcugaug      720

agcaacaacg ugcagaucgu gagacagcag agcuacagca ucaugugcau caucaaggag      780

gaggugcugg ccuacguggu gcagcugccc cuguacggcg ugaucgacac ccccugcugg      840

aagcugcaca ccagcccccu gugcaccacc aacaccaagg agggcagcaa caucugccug      900

accagaaccg acagaggcug guacugcgac aacgccggca gcgugagcuu cuucccccag      960

gccgagaccu gcaaggugug cagcaacaga guguucugcg acaccaugaa cagccugacc     1020

cugcccagcg aggugaaccu gugcaacgug gacaucuuca accccaagua cgacugcaag     1080

aucaugacca gcaagaccga cgugagcagc agcgugauca ccagccuggg cgccaucgug     1140

agcugcuacg gcaagaccaa gugcaccgcc agcaacaaga acaagggcau caucaagacc     1200

uucagcaacg gcugcgacua cgugagcaac aagggcgugg acaccgugag cgugggcaac     1260

acccuguacu acgugaacaa gcaggagggc aagagccugu acgugaaggg cgagcccauc     1320

aucaacuucu acgacccccu gguguucccc agcgacgagu ucgacgccag caucagccag     1380

gugaacgaga agaucaacca gagccuggcc uucaucagaa agagcgacga gcugcugcac     1440

aacgugaacg ccggcaagag caccaccaac aucaugauca ccaccaucau caucgugauc     1500

aucgugaucc ugcugagccu gaucgccgug ggccugcugc uguacugcaa ggccagauga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7537
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt5)

<400>  7537
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug uccgcccuca gaacaggaug guacaccucu      180

guuaucacaa uugaacugag caacaucaag gagaauaaau gcaacggcac cgacgccaag      240

gugaaacuua ucaagcagga acuggauaag uauaaaaaug cugugacgga gcuccagaug      300

cugauguguu ccacccccgc cacagggucu ggaagcgcua uugccuccgg cgucgcggug      360

ugcaagguuc ugcaccucga gggggaagug aacaaaauca agagcgcccu gcuuucuacc      420

aauaaagcug ucgugucccu gagcaacgga guuucugugc ucacauuuaa gguccuggac      480

cuuaagaauu acauugauaa acagcugcuc ccuauccuga acaagcaauc cuguagcauu      540

ucuaauaucg agaccgugau ggaguuccag cagaaaaaca aucggcugcu cgaaauuacg      600

cgcgaguuuu ccgugaacgc cggcgucaca accccgguua gcacauauau gcugaccaau      660

uccgaacuuc ugucucucau caacgacaug cccaucacca acgaucagaa gaaacugaug      720

agcaauaacg ugcaaauugu gagacagcag uccuacagca ucaugugcau uaucaaggag      780

gaaguccuug cuuauguggu ucagcugccu cucuacggcg ugauugacac acccuguugg      840

aaacugcaua cgucuccucu gugcaccaca aauaccaagg agggguccaa caucugucuc      900

acacggaccg aucgcggaug guacugcgac aaugccggca gcgucucuuu cuuuccccaa      960

gcggaaacgu guaaggugug cagcaacaga guuuucugcg auacaaugaa cucccugacc     1020

cuuccuucug aggugaaucu guguaauguc gacaucuuua acccgaaaua ugauugcaag     1080

auuaugacca gcaaaacaga cguguccagc ucugucauca ccucccucgg ggccauugug     1140

agcuguuacg gaaagacaaa augcacggcu ucuaauaaga acaagggcau cauuaaaacc     1200

uucuccaaug ggugugauua uguuagcaac aagggagugg acacagucuc cgugggcaau     1260

acccuguacu auguuaacaa acaggagggc aagucucuuu acgugaaagg ggaacccauc     1320

aucaacuuuu augacccucu ggucuucccc agcgaugagu uugacgccuc cauuucucag     1380

gugaaugaaa agaucaacca aagccucgcu uucauucgga aguccgauga gcugcugcac     1440

aaugugaacg ccggaaaaag cacaaccaau aucaugauua cgaccaucau uaucguuauc     1500

auugucaucc uccugucucu uauugccgug ggccugcucc uguacugcaa ggcucgcuga     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7538
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt6)

<400>  7538
gggagaaagc uuaccaugga auuacuaauc cucaaagcaa acgcaauuac aaccauacua       60

accgcuguca ccuuuuguuu ugccucagga caaaacauaa cugaagaauu uuaccaauca      120

acaugcuccg caguaucuaa aggauaccuc agcgcguuaa gaacaggaug guacacaucg      180

guaauaacca ucgaauuauc caacauaaaa gaaaauaaau gcaauggaac agacgcaaaa      240

gucaaauuaa uuaaacaaga acuagacaaa uauaaaaacg caguaaccga auuacaaaug      300

cuaauguguu caacaccagc aacaggauca ggaucagcua uagcuucagg aguugccgua      360

ugcaaagugc uacacuuaga aggagaagug aauaaaauaa aaucagcucu auuaucaacg      420

aacaaagccg uaguaucucu aucaaauggc guaucaguac ucacauucaa aguacucgac      480

cuaaaaaacu auauagauaa acaacuauua cccauccuaa auaaacaaag cugcucuaua      540

ucaaacaucg aaacaguaau ggaauuucaa caaaaaaaca acagacuacu agaaauaacc      600

cgagaguucu caguuaaugc aggaguaaca acaccagucu caacauacau gcucacaaac      660

ucagaacucc uaucacuaau aaaugacaug ccaauaacaa acgaccaaaa aaaacucaug      720

ucuaacaacg uccaaauagu aagacaacaa uccuacagca uaauguguau aauaaaagaa      780

gaaguuuuag cauacgucgu acaacuaccc uuauauggcg uaauagauac accaugcugg      840

aaacuccaua ccucaccucu auguacaaca aauaccaaag aagguucuaa uauaugccua      900

acacgaacug accgaggaug guacugugac aacgcaggau cagucucuuu cuuuccacaa      960

gcagaaaccu gcaaaguaug caguaaccgc guauuuugcg acacaaugaa cucccuaacc     1020

uuaccaucag aaguaaacuu auguaacgua gacauauuca auccaaaaua ugacugcaaa     1080

auaaugacau caaaaacaga cguaagcuca ucaguaauaa cuucacuagg cgcaauugua     1140

ucaugcuaug gaaaaaccaa auguaccgca uccaacaaaa auaaaggaau aauaaaaacc     1200

uucucuaacg gaugcgacua cguaucaaac aaagguguag auacaguuuc uguaggaaac     1260

acacucuacu auguaaauaa acaagaagga aaaucacuau acguaaaagg agaaccaaua     1320

auaaacuucu augacccacu uguauuucca ucugaugaau uugaugcaag cauaucacaa     1380

guaaacgaaa aaauaaacca aucucuagcc uuuauacgaa aaagcgacga auuacuacau     1440

aacgucaacg cuggaaaauc aacaacaaac auaaugauaa caacaauaau aauaguaaua     1500

auagucaucc uauuaucacu aaucgccgua ggacuacucc uauacugcaa agcuagauaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7539
<211>  1762
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut7 (opt11)

<400>  7539
gggagaaagc uuaccaugga acuccucauc cucaaagcca acgccauaac cacuauccuc       60

acagcaguca cuuucugcuu cgccucagga caaaacauaa ccgaagaguu cuaccaaucc      120

acaugcuccg ccgucuccaa aggcuaccuc ucagcgcucc gcaccggcug guacacaucc      180

gucaucacca ucgaacuaag caacauaaaa gaaaacaaau gcaacggcac cgacgccaaa      240

guuaaacuca ucaagcaaga acucgacaaa uacaaaaacg cagucacaga acuucaaaug      300

cucaugugcu ccacacccgc cacagguucu ggcucagcaa ucgcaagcgg cgucgccgua      360

ugcaaagucc uucaccucga aggcgaaguc aacaaaauca aauccgcccu ccucuccacc      420

aauaaagcug ucgucucacu cuccaacggc gucagcgucc ucacauucaa aguccucgac      480

cucaaaaacu acauagacaa gcaacuccuc ccgauacuca acaaacaaag cugcucuauc      540

uccaacaucg aaaccgucau ggaguuccaa cagaaaaaca aucgucuccu cgaaaucacc      600

cgcgaguucu caguaaacgc cggggucacc acaccagucu ccaccuacau gcucaccaac      660

uccgaacucc uuagccucau aaacgacaug cccauaacca acgaccaaaa gaaacucaug      720

agcaacaacg uacaaauagu ccgacaacaa uccuauucca ucauguguau caucaaagaa      780

gaaguccucg cauacguagu ccaacucccc cuauacggcg uaaucgacac cccauguugg      840

aaacuccaca ccucaccacu cuguaccacc aacaccaaag aaggcucaaa caucugccuc      900

acccgcacag accgcggcug guacugcgac aacgcgggcu ccgucagcuu cuuuccccaa      960

gcggaaaccu gcaaagucug cagcaacaga gucuucugcg acacuaugaa cucccucacc     1020

cuccccucag aagucaaccu cugcaacguc gacaucuuca acccgaaaua cgacugcaaa     1080

aucaugacca gcaaaacuga cgucuccucg uccgucauca ccucacucgg cgcaaucgug     1140

agcugcuacg gcaaaaccaa augcaccgcc uccaacaaaa acaaaggcau cauaaaaaca     1200

uucagcaacg gcugcgacua cgucucgaac aaaggagucg acaccguauc agugggcaac     1260

acccuauacu acguaaacaa gcaagaaggc aaaucacucu acguaaaagg cgaacccauc     1320

aucaacuucu acgacccccu cgucuucccc uccgacgagu ucgacgccuc caucucucaa     1380

gucaacgaga aaaucaacca aucccuugcc uucauacgua aaagcgacga acuccuucac     1440

aacguaaacg ccgggaaauc caccacuaac auaaugauca ccaccaucau caucguuauc     1500

auagucaucc uccucucucu cauagcaguc ggccuacucc uguacugcaa agcgcgcuaa     1560

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1620

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1740

ucuuuucaga gccaccagaa uu                                              1762


<210>  7540
<211>  536
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7540

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Gly 
    130                 135                 140                 


Cys Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr 
145                 150                 155                 160 


Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile 
                165                 170                 175     


Pro Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu 
            180                 185                 190         


Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro 
        195                 200                 205             


Val Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn 
    210                 215                 220                 


Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val 
225                 230                 235                 240 


Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu 
                245                 250                 255     


Glu Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp 
            260                 265                 270         


Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr 
        275                 280                 285             


Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr 
    290                 295                 300                 


Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys 
305                 310                 315                 320 


Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr 
                325                 330                 335     


Leu Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys 
            340                 345                 350         


Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val 
        355                 360                 365             


Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys 
    370                 375                 380                 


Thr Ala Ser Asn Lys Cys Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly 
385                 390                 395                 400 


Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn 
                405                 410                 415     


Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys 
            420                 425                 430         


Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp 
        435                 440                 445             


Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser 
    450                 455                 460                 


Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala 
465                 470                 475                 480 


Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile 
                485                 490                 495     


Ile Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys 
            500                 505                 510         


Lys Ala Arg Ser Thr Pro Val Thr Leu Ser Lys Asp Gln Leu Ser Gly 
        515                 520                 525             


Ile Asn Asn Ile Ala Phe Ser Asn 
    530                 535     


<210>  7541
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7541
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucuccg gcugcggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      540

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      600

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      660

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      780

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      840

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac      900

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc      960

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1020

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1140

aagacgaagu gcaccgccag caacaagugc cgggggauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1260

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1320

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1380

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1440

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1500

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccggagcac gcccgucacc     1560

cuguccaagg accagcugag cggcaucaac aacaucgcgu ucuccaacug a              1611


<210>  7542
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7542
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucgcc uccggcgugg cggugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcccugcugu ccaccaacaa ggccgugguc      420

agccucuccg gcugcggggu gagcgugcug acguucaagg uccuggaccu caagaacuac      480

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      540

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      600

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      660

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggucc agcucccgcu guacggggug aucgacacgc ccugcuggaa gcugcacacc      840

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac      900

cggggcuggu acugcgacaa cgcggggucc gugagcuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1020

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1080

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1140

aagaccaagu gcaccgccag caacaagugc cggggcauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggggucgac acgguguccg ugggcaacac ccucuacuac     1260

gucaacaagc aggaggggca gagccuguac gugaagggcg agcccaucau caacuucuac     1320

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1380

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1440

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1500

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguccac ccccgugacc     1560

cugagcaagg accagcucuc cggcaucaac aacaucgccu ucagcaacug a              1611


<210>  7543
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7543
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucuccg gcugcggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      480

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      540

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      600

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      660

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      720

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      780

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      840

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac      900

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1020

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1140

aagaccaagu gcaccgccuc caacaagugc cgcggcauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1260

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1320

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1380

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1440

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1500

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuccac ccccgucacc     1560

cucuccaagg accagcucuc cggcaucaac aacaucgccu ucuccaacug a              1611


<210>  7544
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7544
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagau caaaugcaau ggcaccgacg ccaaggugaa acuaauaaag      240

caggaacucg auaaguauaa aaacgcagua acugaccugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuaucgca ucaggcgugg ccgucuguaa gguguugcac      360

cucgagggug agguuaauaa aauuaagagc gcucugcuga guacgaacaa agccgugguc      420

ucccucucug ggugcggagu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      480

aucgacaaac aauugcugcc uauucuaaac aagcaguccu guucaauccc aaauauagaa      540

accgugauug aguuccagca gaaaaacaau aggcuccugg aaaucacacg ggaguuuagu      600

gucaacgcgg gcgugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      660

ucccucauua acgauaugcc caucacgaau gaccaaaaga aacugauguc aaacaacguc      720

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagca      780

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      840

ucuccccugu gcaccacuaa uacaaaggaa ggguccaaca ucuguuugac ccgaacggac      900

cguggauggu acugcgauaa ugccgguagc gugucguucu uuccucaggc ugagaccugu      960

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1020

gucaaucucu gcaaugugga uauauuuaac cccaaauaug acuguaagau uaugaccagu     1080

aaaacagaug uaagcuccuc uguuaucacu agccugggcg ccaucguguc augcuacggg     1140

aagaccaaau guacagcaag uaauaagugc aggggaauua ucaagaccuu cuccaacggc     1200

ugugacuaug ucagcaauaa agguguggac acugucucug uggggaacac gcuuuacuau     1260

guuaauaagc aagagggaca gucacuguac gugaaaggcg agccuauuau aaacuuuuau     1320

gauccauugg uauucccgag ugacgaauuu gaugcuagca ucucccaggu caaugagaag     1380

auuaaccagu cucucgccuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcg     1440

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1500

cuaucccuca uagccgucgg gcugcuuuug uacugcaagg cacgcucaac acccgugacc     1560

cugaguaaag aucaacucuc uggaaucaau aacauugcuu ucagcaauug a              1611


<210>  7545
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7545
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagcg gcugcggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      540

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      600

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      660

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      840

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac      900

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc      960

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1020

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1080

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1140

aagaccaagu gcaccgccag caacaagugc agaggcauca ucaagaccuu cagcaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1260

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1320

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1380

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1440

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1500

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagaagcac ccccgugacc     1560

cugagcaagg accagcugag cggcaucaac aacaucgccu ucagcaacug a              1611


<210>  7546
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7546
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagau caaaugcaau gggaccgacg ccaaggugaa acuuauuaag      240

caggaacugg auaaguauaa aaacgcugug acggaccucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuaucgcc agcggggucg cgguguguaa gguucuccac      360

cuggagggag aggugaauaa aauuaagucc gcccuucuga gcaccaacaa agcugucgug      420

ucucucuccg gcugcggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      480

aucgacaaac aacuccugcc uauucugaac aagcagucuu guuccauccc gaauauugaa      540

accgugaucg aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      600

gugaacgccg gggucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      660

agccugauua acgauaugcc uaucaccaau gaccaaaaga aacuuauguc caacaacgug      720

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcu      780

uaugugguuc aacucccccu guacggagug aucgauacac cuuguuggaa acugcauacg      840

agcccccucu gcaccacaaa uaccaaggaa ggcagcaaca uuugucugac acggaccgac      900

cgcggguggu acugcgauaa ugccggaucu gucuccuucu uuccucaggc ggagacgugu      960

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1020

gugaaucucu gcaaugucga uaucuuuaac cccaaauaug acuguaagau uaugaccucc     1080

aaaacagaug ugucuagcuc cgucaucacc agccugggcg ccauuguguc uugcuacggg     1140

aagacaaaau guacggcuuc caauaagugc cggggaauca ucaagaccuu cagcaacggc     1200

ugugacuaug uuucuaauaa aggcguggac acagucuccg uggggaacac ccuuuacuau     1260

guuaauaagc aagagggaca gagccuguac gugaaaggcg agccuauuau caacuuuuau     1320

gauccccucg ucuucccuuc cgacgaauuu gaugccucua uuagccaggu gaaugagaag     1380

aucaaccagu cccuggcuuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcc     1440

gggaagucca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1500

cuuucccuga uugccguggg acuccugcug uacugcaagg cuagaagcac acccgugacc     1560

cuuucuaaag aucaacucuc cggcaucaau aacaucgcgu ucagcaauug a              1611


<210>  7547
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7547
auggaacuau uaauauuaaa agcaaacgca aucacaacua uacuaacagc aguaacauuc       60

ugcuuugccu caggucaaaa cauaacagag gaauuuuacc aauccacaug cucugcugua      120

agcaaaggau accucggagc auuaagaacu ggaugguaca ccucaguaau aacuauagaa      180

cuaucaaaca uaaaagaaau aaaauguaau ggcacagacg caaaagugaa auuaaucaaa      240

caagaacucg auaaauacaa aaaugccgua accgaucucc aacuuuuaau gcaaagcaca      300

cccgcaacag guuccggguc agcaauagca agcggaguug caguaugcaa aguacuacac      360

uuagaaggag aaguaaauaa aaucaaauca gccuuacuau caacaaauaa agcaguugua      420

ucacucucag gaugcggagu auccguacua acauuuaaag uacuagaucu aaaaaacuac      480

auagauaaac aacucuuacc aauacuaaau aaacaaucau guuccauacc caacauagaa      540

accguuaucg aauuucaaca aaaaaacaac agauuacuag aaaucacacg agaauuuuca      600

guaaaugcug gagucacaac accaguuagu acauacaugc ucaccaauuc agaacuacua      660

aguuuaauua acgauaugcc aauaacaaac gaccaaaaaa aacuaauguc aaauaacgua      720

caaauaguaa gacaacaauc auacucaauc augugcauaa uaaaagaaga aguacuagcc      780

uauguagucc aauuaccacu cuacggcgua aucgacaccc caugcuggaa auuacacaca      840

agcccauuau gcaccaccaa cacaaaagaa gguucaaaca uuugcuuaac cagaaccgau      900

cgaggauggu acugcgauaa cgcaggaucu gucuccuuuu ucccacaagc cgaaacaugc      960

aaaguucaau caaaccgagu uuucugugac acuaugaacu cacucacacu uccaagcgaa     1020

guaaaccuau gcaacguaga uauauuuaac ccuaaauacg acugcaaaau aaugacaagc     1080

aaaacagacg uuaguucauc aguaauuaca agucuaggcg caauaguguc augcuacgga     1140

aaaacaaaau gcaccgcauc caauaaaugc cgaggaauca uuaaaacauu cucaaacgga     1200

ugcgacuacg ucagcaauaa aggaguagac acuguuucug uaggaaacac ccuauacuau     1260

guaaacaaac aagaagguca aucacuauac guaaagggag aaccaauuau aaauuuuuac     1320

gaccccuuag uauuuccaag ugaugaauuu gacgcaucua uaagucaagu uaacgaaaaa     1380

auuaaccaau cacuugcauu uauaagaaaa ucagacgaac uacuccauaa uguaaacgca     1440

gguaaaucaa caacaaacau caugaucaca accauaauaa uaguaauaau uguaauauua     1500

cuaucacuaa uagcaguagg auuacuacuc uacugcaaag cuagaucuac cccggucaca     1560

cucucaaaag accaauuauc uggaauaaac aauauagcau ucagcaacua a              1611


<210>  7548
<211>  1611
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F_DSCav1_mut8

<400>  7548
auggaacucc ucauccuuaa agccaacgcc auaaccacca uccucaccgc cgucaccuuc       60

ugcuucgcuu cuggccaaaa cauaaccgaa gaguucuacc aauccacgug cucugccgug      120

ucaaaaggcu accucggagc ccuccgcaca gggugguaca cuuccgucau caccaucgaa      180

cucucuaaca ucaaagaaau caagugcaac ggcacagacg cgaaagucaa gcucaucaaa      240

caagaacuag acaaauacaa aaacgccgua acagaccucc aacuccuaau gcaguccaca      300

ccagccacag gcuccggcag cgccaucgcc uccggcgucg cugucugcaa aguccuacac      360

cucgaaggcg aagucaacaa aaucaaguca gcccuccuua gcaccaacaa agcagucguc      420

ucuuuaagcg ggugcggagu cucuguccua accuuuaaag uacucgaccu caaaaacuac      480

aucgacaaac aacuacuacc aauacuaaac aaacagagcu gcuccauucc caacaucgaa      540

accguuaucg aguuccaaca aaagaacaac cgccuccucg aaaucacccg cgaguucucc      600

gucaacgcag gcgucaccac cccagucucc accuauaugc uaaccaacag cgaacuccuc      660

agccucauca augacaugcc aaucaccaac gaccaaaaga aacucauguc caacaacgua      720

cagauagucc gccagcaguc cuacagcauc augugcauca ucaaagaaga agugcucgcc      780

uacgugguac aacucccucu cuacggaguc auugauacac ccugcuggaa acuccacaca      840

agcccccucu gcacuacaaa caccaaagaa ggcucuaaca uaugccucac ccgcacagac      900

cgugguuggu acugcgacaa cgccggcucc guauccuucu uuccacaagc ugaaaccugc      960

aaaguucaau caaaccgagu cuucugcgac accaugaacu cccucacauu gcccagcgaa     1020

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaaaau caugaccucc     1080

aaaaccgacg ucagcuccag cgugaucaca agccuaggcg cgaucgucag cugcuacggc     1140

aaaaccaaau gcacagccuc caacaaaugc cgcggaauca uaaaaacauu caguaacggc     1200

ugcgacuacg uguccaauaa aggagucgac accguauccg ucggaaacac ccucuacuac     1260

gucaacaaac aagaaggaca aucccucuau gucaaaggcg aacccauuau caacuucuac     1320

gacccccuag uuuuccccuc cgacgaguuc gacgcaagca uuucccaagu caacgaaaag     1380

aucaaucaau cccucgccuu cauacgcaaa agcgacgaac uacuacacaa cguaaacgcc     1440

ggcaaaagca ccaccaacau caugaucaca acaaucauca ucgucaucau cgucauccua     1500

cucucacuca ucgccguugg ccuacuacuc uacugcaaag cccgcuccac acccgucacc     1560

cucucaaaag accaacucuc cggcaucaac aacaucgcau ucagcaacug a              1611


<210>  7549
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7549
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7550
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7550
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7551
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7551
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7552
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7552
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcucaacacc cgugacccug aguaaagauc aacucucugg aaucaauaac auugcuuuca     1680

gcaauugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7553
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7553
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7554
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7554
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaagcacacc cgugacccuu ucuaaagauc aacucuccgg caucaauaac aucgcguuca     1680

gcaauugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7555
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7555
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac      120

uaacagcagu aacauucugc uuugccucag gucaaaacau aacagaggaa uuuuaccaau      180

ccacaugcuc ugcuguaagc aaaggauacc ucggagcauu aagaacugga ugguacaccu      240

caguaauaac uauagaacua ucaaacauaa aagaaauaaa auguaauggc acagacgcaa      300

aagugaaauu aaucaaacaa gaacucgaua aauacaaaaa ugccguaacc gaucuccaac      360

uuuuaaugca aagcacaccc gcaacagguu ccgggucagc aauagcaagc ggaguugcag      420

uaugcaaagu acuacacuua gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa      480

caaauaaagc aguuguauca cucucaggau gcggaguauc cguacuaaca uuuaaaguac      540

uagaucuaaa aaacuacaua gauaaacaac ucuuaccaau acuaaauaaa caaucauguu      600

ccauacccaa cauagaaacc guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa      660

ucacacgaga auuuucagua aaugcuggag ucacaacacc aguuaguaca uacaugcuca      720

ccaauucaga acuacuaagu uuaauuaacg auaugccaau aacaaacgac caaaaaaaac      780

uaaugucaaa uaacguacaa auaguaagac aacaaucaua cucaaucaug ugcauaauaa      840

aagaagaagu acuagccuau guaguccaau uaccacucua cggcguaauc gacaccccau      900

gcuggaaauu acacacaagc ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu      960

gcuuaaccag aaccgaucga ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc     1020

cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacacu augaacucac     1080

ucacacuucc aagcgaagua aaccuaugca acguagauau auuuaacccu aaauacgacu     1140

gcaaaauaau gacaagcaaa acagacguua guucaucagu aauuacaagu cuaggcgcaa     1200

uagugucaug cuacggaaaa acaaaaugca ccgcauccaa uaaaugccga ggaaucauua     1260

aaacauucuc aaacggaugc gacuacguca gcaauaaagg aguagacacu guuucuguag     1320

gaaacacccu auacuaugua aacaaacaag aaggucaauc acuauacgua aagggagaac     1380

caauuauaaa uuuuuacgac cccuuaguau uuccaaguga ugaauuugac gcaucuauaa     1440

gucaaguuaa cgaaaaaauu aaccaaucac uugcauuuau aagaaaauca gacgaacuac     1500

uccauaaugu aaacgcaggu aaaucaacaa caaacaucau gaucacaacc auaauaauag     1560

uaauaauugu aauauuacua ucacuaauag caguaggauu acuacucuac ugcaaagcua     1620

gaucuacccc ggucacacuc ucaaaagacc aauuaucugg aauaaacaau auagcauuca     1680

gcaacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7556
<211>  1887
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7556
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc caacgccaua accaccaucc      120

ucaccgccgu caccuucugc uucgcuucug gccaaaacau aaccgaagag uucuaccaau      180

ccacgugcuc ugccguguca aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu      240

ccgucaucac caucgaacuc ucuaacauca aagaaaucaa gugcaacggc acagacgcga      300

aagucaagcu caucaaacaa gaacuagaca aauacaaaaa cgccguaaca gaccuccaac      360

uccuaaugca guccacacca gccacaggcu ccggcagcgc caucgccucc ggcgucgcug      420

ucugcaaagu ccuacaccuc gaaggcgaag ucaacaaaau caagucagcc cuccuuagca      480

ccaacaaagc agucgucucu uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac      540

ucgaccucaa aaacuacauc gacaaacaac uacuaccaau acuaaacaaa cagagcugcu      600

ccauucccaa caucgaaacc guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucuccguc aacgcaggcg ucaccacccc agucuccacc uauaugcuaa      720

ccaacagcga acuccucagc cucaucaaug acaugccaau caccaacgac caaaagaaac      780

ucauguccaa caacguacag auaguccgcc agcaguccua cagcaucaug ugcaucauca      840

aagaagaagu gcucgccuac gugguacaac ucccucucua cggagucauu gauacacccu      900

gcuggaaacu ccacacaagc ccccucugca cuacaaacac caaagaaggc ucuaacauau      960

gccucacccg cacagaccgu gguugguacu gcgacaacgc cggcuccgua uccuucuuuc     1020

cacaagcuga aaccugcaaa guucaaucaa accgagucuu cugcgacacc augaacuccc     1080

ucacauugcc cagcgaaguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaaaaucau gaccuccaaa accgacguca gcuccagcgu gaucacaagc cuaggcgcga     1200

ucgucagcug cuacggcaaa accaaaugca cagccuccaa caaaugccgc ggaaucauaa     1260

aaacauucag uaacggcugc gacuacgugu ccaauaaagg agucgacacc guauccgucg     1320

gaaacacccu cuacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccauuaucaa cuucuacgac ccccuaguuu uccccuccga cgaguucgac gcaagcauuu     1440

cccaagucaa cgaaaagauc aaucaauccc ucgccuucau acgcaaaagc gacgaacuac     1500

uacacaacgu aaacgccggc aaaagcacca ccaacaucau gaucacaaca aucaucaucg     1560

ucaucaucgu cauccuacuc ucacucaucg ccguuggccu acuacucuac ugcaaagccc     1620

gcuccacacc cgucacccuc ucaaaagacc aacucuccgg caucaacaac aucgcauuca     1680

gcaacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1740

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1860

aaggcucuuu ucagagccac cagaauu                                         1887


<210>  7557
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7557
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7558
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7558
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7559
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7559
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7560
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7560
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cucaacaccc gugacccuga guaaagauca acucucugga     1680

aucaauaaca uugcuuucag caauugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7561
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7561
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7562
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7562
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag aagcacaccc gugacccuuu cuaaagauca acucuccggc     1680

aucaauaaca ucgcguucag caauugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7563
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7563
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aacgcaauca caacuauacu aacagcagua acauucugcu uugccucagg ucaaaacaua      180

acagaggaau uuuaccaauc cacaugcucu gcuguaagca aaggauaccu cggagcauua      240

agaacuggau gguacaccuc aguaauaacu auagaacuau caaacauaaa agaaauaaaa      300

uguaauggca cagacgcaaa agugaaauua aucaaacaag aacucgauaa auacaaaaau      360

gccguaaccg aucuccaacu uuuaaugcaa agcacacccg caacagguuc cgggucagca      420

auagcaagcg gaguugcagu augcaaagua cuacacuuag aaggagaagu aaauaaaauc      480

aaaucagccu uacuaucaac aaauaaagca guuguaucac ucucaggaug cggaguaucc      540

guacuaacau uuaaaguacu agaucuaaaa aacuacauag auaaacaacu cuuaccaaua      600

cuaaauaaac aaucauguuc cauacccaac auagaaaccg uuaucgaauu ucaacaaaaa      660

aacaacagau uacuagaaau cacacgagaa uuuucaguaa augcuggagu cacaacacca      720

guuaguacau acaugcucac caauucagaa cuacuaaguu uaauuaacga uaugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaagua cuagccuaug uaguccaauu accacucuac      900

ggcguaaucg acaccccaug cuggaaauua cacacaagcc cauuaugcac caccaacaca      960

aaagaagguu caaacauuug cuuaaccaga accgaucgag gaugguacug cgauaacgca     1020

ggaucugucu ccuuuuuccc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacua ugaacucacu cacacuucca agcgaaguaa accuaugcaa cguagauaua     1140

uuuaacccua aauacgacug caaaauaaug acaagcaaaa cagacguuag uucaucagua     1200

auuacaaguc uaggcgcaau agugucaugc uacggaaaaa caaaaugcac cgcauccaau     1260

aaaugccgag gaaucauuaa aacauucuca aacggaugcg acuacgucag caauaaagga     1320

guagacacug uuucuguagg aaacacccua uacuauguaa acaaacaaga aggucaauca     1380

cuauacguaa agggagaacc aauuauaaau uuuuacgacc ccuuaguauu uccaagugau     1440

gaauuugacg caucuauaag ucaaguuaac gaaaaaauua accaaucacu ugcauuuaua     1500

agaaaaucag acgaacuacu ccauaaugua aacgcaggua aaucaacaac aaacaucaug     1560

aucacaacca uaauaauagu aauaauugua auauuacuau cacuaauagc aguaggauua     1620

cuacucuacu gcaaagcuag aucuaccccg gucacacucu caaaagacca auuaucugga     1680

auaaacaaua uagcauucag caacuaagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7564
<211>  1906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7564
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagcc      120

aacgccauaa ccaccauccu caccgccguc accuucugcu ucgcuucugg ccaaaacaua      180

accgaagagu ucuaccaauc cacgugcucu gccgugucaa aaggcuaccu cggagcccuc      240

cgcacagggu gguacacuuc cgucaucacc aucgaacucu cuaacaucaa agaaaucaag      300

ugcaacggca cagacgcgaa agucaagcuc aucaaacaag aacuagacaa auacaaaaac      360

gccguaacag accuccaacu ccuaaugcag uccacaccag ccacaggcuc cggcagcgcc      420

aucgccuccg gcgucgcugu cugcaaaguc cuacaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccuuagcac caacaaagca gucgucucuu uaagcgggug cggagucucu      540

guccuaaccu uuaaaguacu cgaccucaaa aacuacaucg acaaacaacu acuaccaaua      600

cuaaacaaac agagcugcuc cauucccaac aucgaaaccg uuaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccacccca      720

gucuccaccu auaugcuaac caacagcgaa cuccucagcc ucaucaauga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaga uaguccgcca gcaguccuac      840

agcaucaugu gcaucaucaa agaagaagug cucgccuacg ugguacaacu cccucucuac      900

ggagucauug auacacccug cuggaaacuc cacacaagcc cccucugcac uacaaacacc      960

aaagaaggcu cuaacauaug ccucacccgc acagaccgug guugguacug cgacaacgcc     1020

ggcuccguau ccuucuuucc acaagcugaa accugcaaag uucaaucaaa ccgagucuuc     1080

ugcgacacca ugaacucccu cacauugccc agcgaaguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caaaaucaug accuccaaaa ccgacgucag cuccagcgug     1200

aucacaagcc uaggcgcgau cgucagcugc uacggcaaaa ccaaaugcac agccuccaac     1260

aaaugccgcg gaaucauaaa aacauucagu aacggcugcg acuacguguc caauaaagga     1320

gucgacaccg uauccgucgg aaacacccuc uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc cauuaucaac uucuacgacc cccuaguuuu ccccuccgac     1440

gaguucgacg caagcauuuc ccaagucaac gaaaagauca aucaaucccu cgccuucaua     1500

cgcaaaagcg acgaacuacu acacaacgua aacgccggca aaagcaccac caacaucaug     1560

aucacaacaa ucaucaucgu caucaucguc auccuacucu cacucaucgc cguuggccua     1620

cuacucuacu gcaaagcccg cuccacaccc gucacccucu caaaagacca acucuccggc     1680

aucaacaaca ucgcauucag caacugagga cuagucccug uucccagagc ccacuuuuuu     1740

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1860

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1906


<210>  7565
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7565
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7566
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7566
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7567
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7567
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7568
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7568
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu caacacccgu gacccugagu     1740

aaagaucaac ucucuggaau caauaacauu gcuuucagca auugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7569
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7569
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7570
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7570
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagaa gcacacccgu gacccuuucu     1740

aaagaucaac ucuccggcau caauaacauc gcguucagca auugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7571
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7571
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa cgcaaucaca acuauacuaa cagcaguaac auucugcuuu      240

gccucagguc aaaacauaac agaggaauuu uaccaaucca caugcucugc uguaagcaaa      300

ggauaccucg gagcauuaag aacuggaugg uacaccucag uaauaacuau agaacuauca      360

aacauaaaag aaauaaaaug uaauggcaca gacgcaaaag ugaaauuaau caaacaagaa      420

cucgauaaau acaaaaaugc cguaaccgau cuccaacuuu uaaugcaaag cacacccgca      480

acagguuccg ggucagcaau agcaagcgga guugcaguau gcaaaguacu acacuuagaa      540

ggagaaguaa auaaaaucaa aucagccuua cuaucaacaa auaaagcagu uguaucacuc      600

ucaggaugcg gaguauccgu acuaacauuu aaaguacuag aucuaaaaaa cuacauagau      660

aaacaacucu uaccaauacu aaauaaacaa ucauguucca uacccaacau agaaaccguu      720

aucgaauuuc aacaaaaaaa caacagauua cuagaaauca cacgagaauu uucaguaaau      780

gcuggaguca caacaccagu uaguacauac augcucacca auucagaacu acuaaguuua      840

auuaacgaua ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguacaaaua      900

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguacu agccuaugua      960

guccaauuac cacucuacgg cguaaucgac accccaugcu ggaaauuaca cacaagccca     1020

uuaugcacca ccaacacaaa agaagguuca aacauuugcu uaaccagaac cgaucgagga     1080

ugguacugcg auaacgcagg aucugucucc uuuuucccac aagccgaaac augcaaaguu     1140

caaucaaacc gaguuuucug ugacacuaug aacucacuca cacuuccaag cgaaguaaac     1200

cuaugcaacg uagauauauu uaacccuaaa uacgacugca aaauaaugac aagcaaaaca     1260

gacguuaguu caucaguaau uacaagucua ggcgcaauag ugucaugcua cggaaaaaca     1320

aaaugcaccg cauccaauaa augccgagga aucauuaaaa cauucucaaa cggaugcgac     1380

uacgucagca auaaaggagu agacacuguu ucuguaggaa acacccuaua cuauguaaac     1440

aaacaagaag gucaaucacu auacguaaag ggagaaccaa uuauaaauuu uuacgacccc     1500

uuaguauuuc caagugauga auuugacgca ucuauaaguc aaguuaacga aaaaauuaac     1560

caaucacuug cauuuauaag aaaaucagac gaacuacucc auaauguaaa cgcagguaaa     1620

ucaacaacaa acaucaugau cacaaccaua auaauaguaa uaauuguaau auuacuauca     1680

cuaauagcag uaggauuacu acucuacugc aaagcuagau cuaccccggu cacacucuca     1740

aaagaccaau uaucuggaau aaacaauaua gcauucagca acuaaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7572
<211>  1984
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7572
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagccaa cgccauaacc accauccuca ccgccgucac cuucugcuuc      240

gcuucuggcc aaaacauaac cgaagaguuc uaccaaucca cgugcucugc cgugucaaaa      300

ggcuaccucg gagcccuccg cacagggugg uacacuuccg ucaucaccau cgaacucucu      360

aacaucaaag aaaucaagug caacggcaca gacgcgaaag ucaagcucau caaacaagaa      420

cuagacaaau acaaaaacgc cguaacagac cuccaacucc uaaugcaguc cacaccagcc      480

acaggcuccg gcagcgccau cgccuccggc gucgcugucu gcaaaguccu acaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cuuagcacca acaaagcagu cgucucuuua      600

agcgggugcg gagucucugu ccuaaccuuu aaaguacucg accucaaaaa cuacaucgac      660

aaacaacuac uaccaauacu aaacaaacag agcugcucca uucccaacau cgaaaccguu      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cccgcgaguu cuccgucaac      780

gcaggcguca ccaccccagu cuccaccuau augcuaacca acagcgaacu ccucagccuc      840

aucaaugaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacagaua      900

guccgccagc aguccuacag caucaugugc aucaucaaag aagaagugcu cgccuacgug      960

guacaacucc cucucuacgg agucauugau acacccugcu ggaaacucca cacaagcccc     1020

cucugcacua caaacaccaa agaaggcucu aacauaugcc ucacccgcac agaccguggu     1080

ugguacugcg acaacgccgg cuccguaucc uucuuuccac aagcugaaac cugcaaaguu     1140

caaucaaacc gagucuucug cgacaccaug aacucccuca cauugcccag cgaagucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca aaaucaugac cuccaaaacc     1260

gacgucagcu ccagcgugau cacaagccua ggcgcgaucg ucagcugcua cggcaaaacc     1320

aaaugcacag ccuccaacaa augccgcgga aucauaaaaa cauucaguaa cggcugcgac     1380

uacgugucca auaaaggagu cgacaccgua uccgucggaa acacccucua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca uuaucaacuu cuacgacccc     1500

cuaguuuucc ccuccgacga guucgacgca agcauuuccc aagucaacga aaagaucaau     1560

caaucccucg ccuucauacg caaaagcgac gaacuacuac acaacguaaa cgccggcaaa     1620

agcaccacca acaucaugau cacaacaauc aucaucguca ucaucgucau ccuacucuca     1680

cucaucgccg uuggccuacu acucuacugc aaagcccgcu ccacacccgu cacccucuca     1740

aaagaccaac ucuccggcau caacaacauc gcauucagca acugaggacu agucccuguu     1800

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1980

aauu                                                                  1984


<210>  7573
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7573
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7574
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7574
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccgguc cacccccgug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7575
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7575
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7576
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7576
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcuc aacacccgug     1680

acccugagua aagaucaacu cucuggaauc aauaacauug cuuucagcaa uugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7577
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7577
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7578
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7578
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaag cacacccgug     1680

acccuuucua aagaucaacu cuccggcauc aauaacaucg cguucagcaa uugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7579
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7579
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaac gcaaucacaa cuauacuaac agcaguaaca      180

uucugcuuug ccucagguca aaacauaaca gaggaauuuu accaauccac augcucugcu      240

guaagcaaag gauaccucgg agcauuaaga acuggauggu acaccucagu aauaacuaua      300

gaacuaucaa acauaaaaga aauaaaaugu aauggcacag acgcaaaagu gaaauuaauc      360

aaacaagaac ucgauaaaua caaaaaugcc guaaccgauc uccaacuuuu aaugcaaagc      420

acacccgcaa cagguuccgg gucagcaaua gcaagcggag uugcaguaug caaaguacua      480

cacuuagaag gagaaguaaa uaaaaucaaa ucagccuuac uaucaacaaa uaaagcaguu      540

guaucacucu caggaugcgg aguauccgua cuaacauuua aaguacuaga ucuaaaaaac      600

uacauagaua aacaacucuu accaauacua aauaaacaau cauguuccau acccaacaua      660

gaaaccguua ucgaauuuca acaaaaaaac aacagauuac uagaaaucac acgagaauuu      720

ucaguaaaug cuggagucac aacaccaguu aguacauaca ugcucaccaa uucagaacua      780

cuaaguuuaa uuaacgauau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      840

guacaaauag uaagacaaca aucauacuca aucaugugca uaauaaaaga agaaguacua      900

gccuauguag uccaauuacc acucuacggc guaaucgaca ccccaugcug gaaauuacac      960

acaagcccau uaugcaccac caacacaaaa gaagguucaa acauuugcuu aaccagaacc     1020

gaucgaggau gguacugcga uaacgcagga ucugucuccu uuuucccaca agccgaaaca     1080

ugcaaaguuc aaucaaaccg aguuuucugu gacacuauga acucacucac acuuccaagc     1140

gaaguaaacc uaugcaacgu agauauauuu aacccuaaau acgacugcaa aauaaugaca     1200

agcaaaacag acguuaguuc aucaguaauu acaagucuag gcgcaauagu gucaugcuac     1260

ggaaaaacaa aaugcaccgc auccaauaaa ugccgaggaa ucauuaaaac auucucaaac     1320

ggaugcgacu acgucagcaa uaaaggagua gacacuguuu cuguaggaaa cacccuauac     1380

uauguaaaca aacaagaagg ucaaucacua uacguaaagg gagaaccaau uauaaauuuu     1440

uacgaccccu uaguauuucc aagugaugaa uuugacgcau cuauaaguca aguuaacgaa     1500

aaaauuaacc aaucacuugc auuuauaaga aaaucagacg aacuacucca uaauguaaac     1560

gcagguaaau caacaacaaa caucaugauc acaaccauaa uaauaguaau aauuguaaua     1620

uuacuaucac uaauagcagu aggauuacua cucuacugca aagcuagauc uaccccgguc     1680

acacucucaa aagaccaauu aucuggaaua aacaauauag cauucagcaa cuaaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7580
<211>  1933
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7580
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagccaac gccauaacca ccauccucac cgccgucacc      180

uucugcuucg cuucuggcca aaacauaacc gaagaguucu accaauccac gugcucugcc      240

gugucaaaag gcuaccucgg agcccuccgc acaggguggu acacuuccgu caucaccauc      300

gaacucucua acaucaaaga aaucaagugc aacggcacag acgcgaaagu caagcucauc      360

aaacaagaac uagacaaaua caaaaacgcc guaacagacc uccaacuccu aaugcagucc      420

acaccagcca caggcuccgg cagcgccauc gccuccggcg ucgcugucug caaaguccua      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc uuagcaccaa caaagcaguc      540

gucucuuuaa gcgggugcgg agucucuguc cuaaccuuua aaguacucga ccucaaaaac      600

uacaucgaca aacaacuacu accaauacua aacaaacaga gcugcuccau ucccaacauc      660

gaaaccguua ucgaguucca acaaaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

uccgucaacg caggcgucac caccccaguc uccaccuaua ugcuaaccaa cagcgaacuc      780

cucagccuca ucaaugacau gccaaucacc aacgaccaaa agaaacucau guccaacaac      840

guacagauag uccgccagca guccuacagc aucaugugca ucaucaaaga agaagugcuc      900

gccuacgugg uacaacuccc ucucuacgga gucauugaua cacccugcug gaaacuccac      960

acaagccccc ucugcacuac aaacaccaaa gaaggcucua acauaugccu cacccgcaca     1020

gaccgugguu gguacugcga caacgccggc uccguauccu ucuuuccaca agcugaaacc     1080

ugcaaaguuc aaucaaaccg agucuucugc gacaccauga acucccucac auugcccagc     1140

gaagucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa aaucaugacc     1200

uccaaaaccg acgucagcuc cagcgugauc acaagccuag gcgcgaucgu cagcugcuac     1260

ggcaaaacca aaugcacagc cuccaacaaa ugccgcggaa ucauaaaaac auucaguaac     1320

ggcugcgacu acguguccaa uaaaggaguc gacaccguau ccgucggaaa cacccucuac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau uaucaacuuc     1440

uacgaccccc uaguuuuccc cuccgacgag uucgacgcaa gcauuuccca agucaacgaa     1500

aagaucaauc aaucccucgc cuucauacgc aaaagcgacg aacuacuaca caacguaaac     1560

gccggcaaaa gcaccaccaa caucaugauc acaacaauca ucaucgucau caucgucauc     1620

cuacucucac ucaucgccgu uggccuacua cucuacugca aagcccgcuc cacacccguc     1680

acccucucaa aagaccaacu cuccggcauc aacaacaucg cauucagcaa cugaggacua     1740

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca     1800

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1920

agccaccaga auu                                                        1933


<210>  7581
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7581
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7582
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7582
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccgguccacc     1620

cccgugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7583
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7583
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7584
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7584
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcucaaca     1620

cccgugaccc ugaguaaaga ucaacucucu ggaaucaaua acauugcuuu cagcaauuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7585
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7585
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7586
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7586
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaagcaca     1620

cccgugaccc uuucuaaaga ucaacucucc ggcaucaaua acaucgcguu cagcaauuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7587
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7587
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaacgcaa ucacaacuau acuaacagca      120

guaacauucu gcuuugccuc aggucaaaac auaacagagg aauuuuacca auccacaugc      180

ucugcuguaa gcaaaggaua ccucggagca uuaagaacug gaugguacac cucaguaaua      240

acuauagaac uaucaaacau aaaagaaaua aaauguaaug gcacagacgc aaaagugaaa      300

uuaaucaaac aagaacucga uaaauacaaa aaugccguaa ccgaucucca acuuuuaaug      360

caaagcacac ccgcaacagg uuccggguca gcaauagcaa gcggaguugc aguaugcaaa      420

guacuacacu uagaaggaga aguaaauaaa aucaaaucag ccuuacuauc aacaaauaaa      480

gcaguuguau cacucucagg augcggagua uccguacuaa cauuuaaagu acuagaucua      540

aaaaacuaca uagauaaaca acucuuacca auacuaaaua aacaaucaug uuccauaccc      600

aacauagaaa ccguuaucga auuucaacaa aaaaacaaca gauuacuaga aaucacacga      660

gaauuuucag uaaaugcugg agucacaaca ccaguuagua cauacaugcu caccaauuca      720

gaacuacuaa guuuaauuaa cgauaugcca auaacaaacg accaaaaaaa acuaauguca      780

aauaacguac aaauaguaag acaacaauca uacucaauca ugugcauaau aaaagaagaa      840

guacuagccu auguagucca auuaccacuc uacggcguaa ucgacacccc augcuggaaa      900

uuacacacaa gcccauuaug caccaccaac acaaaagaag guucaaacau uugcuuaacc      960

agaaccgauc gaggauggua cugcgauaac gcaggaucug ucuccuuuuu cccacaagcc     1020

gaaacaugca aaguucaauc aaaccgaguu uucugugaca cuaugaacuc acucacacuu     1080

ccaagcgaag uaaaccuaug caacguagau auauuuaacc cuaaauacga cugcaaaaua     1140

augacaagca aaacagacgu uaguucauca guaauuacaa gucuaggcgc aauaguguca     1200

ugcuacggaa aaacaaaaug caccgcaucc aauaaaugcc gaggaaucau uaaaacauuc     1260

ucaaacggau gcgacuacgu cagcaauaaa ggaguagaca cuguuucugu aggaaacacc     1320

cuauacuaug uaaacaaaca agaaggucaa ucacuauacg uaaagggaga accaauuaua     1380

aauuuuuacg accccuuagu auuuccaagu gaugaauuug acgcaucuau aagucaaguu     1440

aacgaaaaaa uuaaccaauc acuugcauuu auaagaaaau cagacgaacu acuccauaau     1500

guaaacgcag guaaaucaac aacaaacauc augaucacaa ccauaauaau aguaauaauu     1560

guaauauuac uaucacuaau agcaguagga uuacuacucu acugcaaagc uagaucuacc     1620

ccggucacac ucucaaaaga ccaauuaucu ggaauaaaca auauagcauu cagcaacuaa     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7588
<211>  1879
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7588
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gccaacgcca uaaccaccau ccucaccgcc      120

gucaccuucu gcuucgcuuc uggccaaaac auaaccgaag aguucuacca auccacgugc      180

ucugccgugu caaaaggcua ccucggagcc cuccgcacag ggugguacac uuccgucauc      240

accaucgaac ucucuaacau caaagaaauc aagugcaacg gcacagacgc gaaagucaag      300

cucaucaaac aagaacuaga caaauacaaa aacgccguaa cagaccucca acuccuaaug      360

caguccacac cagccacagg cuccggcagc gccaucgccu ccggcgucgc ugucugcaaa      420

guccuacacc ucgaaggcga agucaacaaa aucaagucag cccuccuuag caccaacaaa      480

gcagucgucu cuuuaagcgg gugcggaguc ucuguccuaa ccuuuaaagu acucgaccuc      540

aaaaacuaca ucgacaaaca acuacuacca auacuaaaca aacagagcug cuccauuccc      600

aacaucgaaa ccguuaucga guuccaacaa aagaacaacc gccuccucga aaucacccgc      660

gaguucuccg ucaacgcagg cgucaccacc ccagucucca ccuauaugcu aaccaacagc      720

gaacuccuca gccucaucaa ugacaugcca aucaccaacg accaaaagaa acucaugucc      780

aacaacguac agauaguccg ccagcagucc uacagcauca ugugcaucau caaagaagaa      840

gugcucgccu acgugguaca acucccucuc uacggaguca uugauacacc cugcuggaaa      900

cuccacacaa gcccccucug cacuacaaac accaaagaag gcucuaacau augccucacc      960

cgcacagacc gugguuggua cugcgacaac gccggcuccg uauccuucuu uccacaagcu     1020

gaaaccugca aaguucaauc aaaccgaguc uucugcgaca ccaugaacuc ccucacauug     1080

cccagcgaag ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaaaauc     1140

augaccucca aaaccgacgu cagcuccagc gugaucacaa gccuaggcgc gaucgucagc     1200

ugcuacggca aaaccaaaug cacagccucc aacaaaugcc gcggaaucau aaaaacauuc     1260

aguaacggcu gcgacuacgu guccaauaaa ggagucgaca ccguauccgu cggaaacacc     1320

cucuacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccauuauc     1380

aacuucuacg acccccuagu uuuccccucc gacgaguucg acgcaagcau uucccaaguc     1440

aacgaaaaga ucaaucaauc ccucgccuuc auacgcaaaa gcgacgaacu acuacacaac     1500

guaaacgccg gcaaaagcac caccaacauc augaucacaa caaucaucau cgucaucauc     1560

gucauccuac ucucacucau cgccguuggc cuacuacucu acugcaaagc ccgcuccaca     1620

cccgucaccc ucucaaaaga ccaacucucc ggcaucaaca acaucgcauu cagcaacuga     1680

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu     1740

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1860

uuucagagcc accagaauu                                                  1879


<210>  7589
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7589
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1800

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7590
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7590
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      660

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      720

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      780

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      840

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc     1080

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg     1140

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1380

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1500

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1620

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1680

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1740

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguccacccc cgugacccug     1800

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7591
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7591
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1800

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7592
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7592
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      480

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      600

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      660

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      720

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      780

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      840

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      900

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      960

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau     1020

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu     1080

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu     1140

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1200

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1260

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1320

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1380

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1440

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1500

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1560

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1620

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1680

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1740

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcucaacacc cgugacccug     1800

aguaaagauc aacucucugg aaucaauaac auugcuuuca gcaauugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7593
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7593
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1800

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7594
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7594
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      480

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      600

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      660

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      720

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      780

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      840

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      900

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      960

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau     1020

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc     1080

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc     1140

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1200

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1260

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1320

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1380

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1440

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1500

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1560

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1620

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1680

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1740

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaagcacacc cgugacccuu     1800

ucuaaagauc aacucuccgg caucaauaac aucgcguuca gcaauugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7595
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7595
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac uaacagcagu aacauucugc      300

uuugccucag gucaaaacau aacagaggaa uuuuaccaau ccacaugcuc ugcuguaagc      360

aaaggauacc ucggagcauu aagaacugga ugguacaccu caguaauaac uauagaacua      420

ucaaacauaa aagaaauaaa auguaauggc acagacgcaa aagugaaauu aaucaaacaa      480

gaacucgaua aauacaaaaa ugccguaacc gaucuccaac uuuuaaugca aagcacaccc      540

gcaacagguu ccgggucagc aauagcaagc ggaguugcag uaugcaaagu acuacacuua      600

gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa caaauaaagc aguuguauca      660

cucucaggau gcggaguauc cguacuaaca uuuaaaguac uagaucuaaa aaacuacaua      720

gauaaacaac ucuuaccaau acuaaauaaa caaucauguu ccauacccaa cauagaaacc      780

guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa ucacacgaga auuuucagua      840

aaugcuggag ucacaacacc aguuaguaca uacaugcuca ccaauucaga acuacuaagu      900

uuaauuaacg auaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      960

auaguaagac aacaaucaua cucaaucaug ugcauaauaa aagaagaagu acuagccuau     1020

guaguccaau uaccacucua cggcguaauc gacaccccau gcuggaaauu acacacaagc     1080

ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu gcuuaaccag aaccgaucga     1140

ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc cacaagccga aacaugcaaa     1200

guucaaucaa accgaguuuu cugugacacu augaacucac ucacacuucc aagcgaagua     1260

aaccuaugca acguagauau auuuaacccu aaauacgacu gcaaaauaau gacaagcaaa     1320

acagacguua guucaucagu aauuacaagu cuaggcgcaa uagugucaug cuacggaaaa     1380

acaaaaugca ccgcauccaa uaaaugccga ggaaucauua aaacauucuc aaacggaugc     1440

gacuacguca gcaauaaagg aguagacacu guuucuguag gaaacacccu auacuaugua     1500

aacaaacaag aaggucaauc acuauacgua aagggagaac caauuauaaa uuuuuacgac     1560

cccuuaguau uuccaaguga ugaauuugac gcaucuauaa gucaaguuaa cgaaaaaauu     1620

aaccaaucac uugcauuuau aagaaaauca gacgaacuac uccauaaugu aaacgcaggu     1680

aaaucaacaa caaacaucau gaucacaacc auaauaauag uaauaauugu aauauuacua     1740

ucacuaauag caguaggauu acuacucuac ugcaaagcua gaucuacccc ggucacacuc     1800

ucaaaagacc aauuaucugg aauaaacaau auagcauuca gcaacuaagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7596
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7596
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccuuaaagc caacgccaua accaccaucc ucaccgccgu caccuucugc      300

uucgcuucug gccaaaacau aaccgaagag uucuaccaau ccacgugcuc ugccguguca      360

aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu ccgucaucac caucgaacuc      420

ucuaacauca aagaaaucaa gugcaacggc acagacgcga aagucaagcu caucaaacaa      480

gaacuagaca aauacaaaaa cgccguaaca gaccuccaac uccuaaugca guccacacca      540

gccacaggcu ccggcagcgc caucgccucc ggcgucgcug ucugcaaagu ccuacaccuc      600

gaaggcgaag ucaacaaaau caagucagcc cuccuuagca ccaacaaagc agucgucucu      660

uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac ucgaccucaa aaacuacauc      720

gacaaacaac uacuaccaau acuaaacaaa cagagcugcu ccauucccaa caucgaaacc      780

guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa ucacccgcga guucuccguc      840

aacgcaggcg ucaccacccc agucuccacc uauaugcuaa ccaacagcga acuccucagc      900

cucaucaaug acaugccaau caccaacgac caaaagaaac ucauguccaa caacguacag      960

auaguccgcc agcaguccua cagcaucaug ugcaucauca aagaagaagu gcucgccuac     1020

gugguacaac ucccucucua cggagucauu gauacacccu gcuggaaacu ccacacaagc     1080

ccccucugca cuacaaacac caaagaaggc ucuaacauau gccucacccg cacagaccgu     1140

gguugguacu gcgacaacgc cggcuccgua uccuucuuuc cacaagcuga aaccugcaaa     1200

guucaaucaa accgagucuu cugcgacacc augaacuccc ucacauugcc cagcgaaguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaaaaucau gaccuccaaa     1320

accgacguca gcuccagcgu gaucacaagc cuaggcgcga ucgucagcug cuacggcaaa     1380

accaaaugca cagccuccaa caaaugccgc ggaaucauaa aaacauucag uaacggcugc     1440

gacuacgugu ccaauaaagg agucgacacc guauccgucg gaaacacccu cuacuacguc     1500

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccauuaucaa cuucuacgac     1560

ccccuaguuu uccccuccga cgaguucgac gcaagcauuu cccaagucaa cgaaaagauc     1620

aaucaauccc ucgccuucau acgcaaaagc gacgaacuac uacacaacgu aaacgccggc     1680

aaaagcacca ccaacaucau gaucacaaca aucaucaucg ucaucaucgu cauccuacuc     1740

ucacucaucg ccguuggccu acuacucuac ugcaaagccc gcuccacacc cgucacccuc     1800

ucaaaagacc aacucuccgg caucaacaac aucgcauuca gcaacugagg acuagugucc     1860

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1920

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7597
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7597
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1620

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7598
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7598
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      480

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1200

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1320

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguccacccc cgugacccug     1620

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7599
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7599
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1620

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7600
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7600
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      480

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      540

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      600

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      660

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      720

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      780

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau      840

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      900

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu      960

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1020

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1080

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1140

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1200

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1260

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1320

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1380

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1440

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1500

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1560

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcucaacacc cgugacccug     1620

aguaaagauc aacucucugg aaucaauaac auugcuuuca gcaauugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7601
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7601
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1620

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7602
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7602
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      480

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      540

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      600

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      660

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      720

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      780

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau      840

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc      900

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc      960

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1020

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1080

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1140

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1200

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1260

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1320

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1380

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1440

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1500

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1560

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaagcacacc cgugacccuu     1620

ucuaaagauc aacucuccgg caucaauaac aucgcguuca gcaauugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7603
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7603
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac uaacagcagu aacauucugc      120

uuugccucag gucaaaacau aacagaggaa uuuuaccaau ccacaugcuc ugcuguaagc      180

aaaggauacc ucggagcauu aagaacugga ugguacaccu caguaauaac uauagaacua      240

ucaaacauaa aagaaauaaa auguaauggc acagacgcaa aagugaaauu aaucaaacaa      300

gaacucgaua aauacaaaaa ugccguaacc gaucuccaac uuuuaaugca aagcacaccc      360

gcaacagguu ccgggucagc aauagcaagc ggaguugcag uaugcaaagu acuacacuua      420

gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa caaauaaagc aguuguauca      480

cucucaggau gcggaguauc cguacuaaca uuuaaaguac uagaucuaaa aaacuacaua      540

gauaaacaac ucuuaccaau acuaaauaaa caaucauguu ccauacccaa cauagaaacc      600

guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa ucacacgaga auuuucagua      660

aaugcuggag ucacaacacc aguuaguaca uacaugcuca ccaauucaga acuacuaagu      720

uuaauuaacg auaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      780

auaguaagac aacaaucaua cucaaucaug ugcauaauaa aagaagaagu acuagccuau      840

guaguccaau uaccacucua cggcguaauc gacaccccau gcuggaaauu acacacaagc      900

ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu gcuuaaccag aaccgaucga      960

ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc cacaagccga aacaugcaaa     1020

guucaaucaa accgaguuuu cugugacacu augaacucac ucacacuucc aagcgaagua     1080

aaccuaugca acguagauau auuuaacccu aaauacgacu gcaaaauaau gacaagcaaa     1140

acagacguua guucaucagu aauuacaagu cuaggcgcaa uagugucaug cuacggaaaa     1200

acaaaaugca ccgcauccaa uaaaugccga ggaaucauua aaacauucuc aaacggaugc     1260

gacuacguca gcaauaaagg aguagacacu guuucuguag gaaacacccu auacuaugua     1320

aacaaacaag aaggucaauc acuauacgua aagggagaac caauuauaaa uuuuuacgac     1380

cccuuaguau uuccaaguga ugaauuugac gcaucuauaa gucaaguuaa cgaaaaaauu     1440

aaccaaucac uugcauuuau aagaaaauca gacgaacuac uccauaaugu aaacgcaggu     1500

aaaucaacaa caaacaucau gaucacaacc auaauaauag uaauaauugu aauauuacua     1560

ucacuaauag caguaggauu acuacucuac ugcaaagcua gaucuacccc ggucacacuc     1620

ucaaaagacc aauuaucugg aauaaacaau auagcauuca gcaacuaagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7604
<211>  1880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7604
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccuuaaagc caacgccaua accaccaucc ucaccgccgu caccuucugc      120

uucgcuucug gccaaaacau aaccgaagag uucuaccaau ccacgugcuc ugccguguca      180

aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu ccgucaucac caucgaacuc      240

ucuaacauca aagaaaucaa gugcaacggc acagacgcga aagucaagcu caucaaacaa      300

gaacuagaca aauacaaaaa cgccguaaca gaccuccaac uccuaaugca guccacacca      360

gccacaggcu ccggcagcgc caucgccucc ggcgucgcug ucugcaaagu ccuacaccuc      420

gaaggcgaag ucaacaaaau caagucagcc cuccuuagca ccaacaaagc agucgucucu      480

uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac ucgaccucaa aaacuacauc      540

gacaaacaac uacuaccaau acuaaacaaa cagagcugcu ccauucccaa caucgaaacc      600

guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa ucacccgcga guucuccguc      660

aacgcaggcg ucaccacccc agucuccacc uauaugcuaa ccaacagcga acuccucagc      720

cucaucaaug acaugccaau caccaacgac caaaagaaac ucauguccaa caacguacag      780

auaguccgcc agcaguccua cagcaucaug ugcaucauca aagaagaagu gcucgccuac      840

gugguacaac ucccucucua cggagucauu gauacacccu gcuggaaacu ccacacaagc      900

ccccucugca cuacaaacac caaagaaggc ucuaacauau gccucacccg cacagaccgu      960

gguugguacu gcgacaacgc cggcuccgua uccuucuuuc cacaagcuga aaccugcaaa     1020

guucaaucaa accgagucuu cugcgacacc augaacuccc ucacauugcc cagcgaaguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaaaaucau gaccuccaaa     1140

accgacguca gcuccagcgu gaucacaagc cuaggcgcga ucgucagcug cuacggcaaa     1200

accaaaugca cagccuccaa caaaugccgc ggaaucauaa aaacauucag uaacggcugc     1260

gacuacgugu ccaauaaagg agucgacacc guauccgucg gaaacacccu cuacuacguc     1320

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccauuaucaa cuucuacgac     1380

ccccuaguuu uccccuccga cgaguucgac gcaagcauuu cccaagucaa cgaaaagauc     1440

aaucaauccc ucgccuucau acgcaaaagc gacgaacuac uacacaacgu aaacgccggc     1500

aaaagcacca ccaacaucau gaucacaaca aucaucaucg ucaucaucgu cauccuacuc     1560

ucacucaucg ccguuggccu acuacucuac ugcaaagccc gcuccacacc cgucacccuc     1620

ucaaaagacc aacucuccgg caucaacaac aucgcauuca gcaacugagg acuagugucc     1680

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1740

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1860

uuuucagagc caccagaauu                                                 1880


<210>  7605
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7605
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7606
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7606
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7607
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7607
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7608
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7608
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcucaacacc cgugacccug aguaaagauc aacucucugg aaucaauaac auugcuuuca     1680

gcaauugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7609
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7609
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7610
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7610
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaagcacacc cgugacccuu ucuaaagauc aacucuccgg caucaauaac aucgcguuca     1680

gcaauugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7611
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7611
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac      120

uaacagcagu aacauucugc uuugccucag gucaaaacau aacagaggaa uuuuaccaau      180

ccacaugcuc ugcuguaagc aaaggauacc ucggagcauu aagaacugga ugguacaccu      240

caguaauaac uauagaacua ucaaacauaa aagaaauaaa auguaauggc acagacgcaa      300

aagugaaauu aaucaaacaa gaacucgaua aauacaaaaa ugccguaacc gaucuccaac      360

uuuuaaugca aagcacaccc gcaacagguu ccgggucagc aauagcaagc ggaguugcag      420

uaugcaaagu acuacacuua gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa      480

caaauaaagc aguuguauca cucucaggau gcggaguauc cguacuaaca uuuaaaguac      540

uagaucuaaa aaacuacaua gauaaacaac ucuuaccaau acuaaauaaa caaucauguu      600

ccauacccaa cauagaaacc guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa      660

ucacacgaga auuuucagua aaugcuggag ucacaacacc aguuaguaca uacaugcuca      720

ccaauucaga acuacuaagu uuaauuaacg auaugccaau aacaaacgac caaaaaaaac      780

uaaugucaaa uaacguacaa auaguaagac aacaaucaua cucaaucaug ugcauaauaa      840

aagaagaagu acuagccuau guaguccaau uaccacucua cggcguaauc gacaccccau      900

gcuggaaauu acacacaagc ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu      960

gcuuaaccag aaccgaucga ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc     1020

cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacacu augaacucac     1080

ucacacuucc aagcgaagua aaccuaugca acguagauau auuuaacccu aaauacgacu     1140

gcaaaauaau gacaagcaaa acagacguua guucaucagu aauuacaagu cuaggcgcaa     1200

uagugucaug cuacggaaaa acaaaaugca ccgcauccaa uaaaugccga ggaaucauua     1260

aaacauucuc aaacggaugc gacuacguca gcaauaaagg aguagacacu guuucuguag     1320

gaaacacccu auacuaugua aacaaacaag aaggucaauc acuauacgua aagggagaac     1380

caauuauaaa uuuuuacgac cccuuaguau uuccaaguga ugaauuugac gcaucuauaa     1440

gucaaguuaa cgaaaaaauu aaccaaucac uugcauuuau aagaaaauca gacgaacuac     1500

uccauaaugu aaacgcaggu aaaucaacaa caaacaucau gaucacaacc auaauaauag     1560

uaauaauugu aauauuacua ucacuaauag caguaggauu acuacucuac ugcaaagcua     1620

gaucuacccc ggucacacuc ucaaaagacc aauuaucugg aauaaacaau auagcauuca     1680

gcaacuaagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7612
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7612
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc caacgccaua accaccaucc      120

ucaccgccgu caccuucugc uucgcuucug gccaaaacau aaccgaagag uucuaccaau      180

ccacgugcuc ugccguguca aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu      240

ccgucaucac caucgaacuc ucuaacauca aagaaaucaa gugcaacggc acagacgcga      300

aagucaagcu caucaaacaa gaacuagaca aauacaaaaa cgccguaaca gaccuccaac      360

uccuaaugca guccacacca gccacaggcu ccggcagcgc caucgccucc ggcgucgcug      420

ucugcaaagu ccuacaccuc gaaggcgaag ucaacaaaau caagucagcc cuccuuagca      480

ccaacaaagc agucgucucu uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac      540

ucgaccucaa aaacuacauc gacaaacaac uacuaccaau acuaaacaaa cagagcugcu      600

ccauucccaa caucgaaacc guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucuccguc aacgcaggcg ucaccacccc agucuccacc uauaugcuaa      720

ccaacagcga acuccucagc cucaucaaug acaugccaau caccaacgac caaaagaaac      780

ucauguccaa caacguacag auaguccgcc agcaguccua cagcaucaug ugcaucauca      840

aagaagaagu gcucgccuac gugguacaac ucccucucua cggagucauu gauacacccu      900

gcuggaaacu ccacacaagc ccccucugca cuacaaacac caaagaaggc ucuaacauau      960

gccucacccg cacagaccgu gguugguacu gcgacaacgc cggcuccgua uccuucuuuc     1020

cacaagcuga aaccugcaaa guucaaucaa accgagucuu cugcgacacc augaacuccc     1080

ucacauugcc cagcgaaguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaaaaucau gaccuccaaa accgacguca gcuccagcgu gaucacaagc cuaggcgcga     1200

ucgucagcug cuacggcaaa accaaaugca cagccuccaa caaaugccgc ggaaucauaa     1260

aaacauucag uaacggcugc gacuacgugu ccaauaaagg agucgacacc guauccgucg     1320

gaaacacccu cuacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccauuaucaa cuucuacgac ccccuaguuu uccccuccga cgaguucgac gcaagcauuu     1440

cccaagucaa cgaaaagauc aaucaauccc ucgccuucau acgcaaaagc gacgaacuac     1500

uacacaacgu aaacgccggc aaaagcacca ccaacaucau gaucacaaca aucaucaucg     1560

ucaucaucgu cauccuacuc ucacucaucg ccguuggccu acuacucuac ugcaaagccc     1620

gcuccacacc cgucacccuc ucaaaagacc aacucuccgg caucaacaac aucgcauuca     1680

gcaacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug     1740

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7613
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7613
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7614
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7614
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7615
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7615
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7616
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7616
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcucaacacc cgugacccug aguaaagauc aacucucugg aaucaauaac auugcuuuca     1680

gcaauugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7617
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7617
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7618
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7618
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaagcacacc cgugacccuu ucuaaagauc aacucuccgg caucaauaac aucgcguuca     1680

gcaauugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7619
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7619
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac      120

uaacagcagu aacauucugc uuugccucag gucaaaacau aacagaggaa uuuuaccaau      180

ccacaugcuc ugcuguaagc aaaggauacc ucggagcauu aagaacugga ugguacaccu      240

caguaauaac uauagaacua ucaaacauaa aagaaauaaa auguaauggc acagacgcaa      300

aagugaaauu aaucaaacaa gaacucgaua aauacaaaaa ugccguaacc gaucuccaac      360

uuuuaaugca aagcacaccc gcaacagguu ccgggucagc aauagcaagc ggaguugcag      420

uaugcaaagu acuacacuua gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa      480

caaauaaagc aguuguauca cucucaggau gcggaguauc cguacuaaca uuuaaaguac      540

uagaucuaaa aaacuacaua gauaaacaac ucuuaccaau acuaaauaaa caaucauguu      600

ccauacccaa cauagaaacc guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa      660

ucacacgaga auuuucagua aaugcuggag ucacaacacc aguuaguaca uacaugcuca      720

ccaauucaga acuacuaagu uuaauuaacg auaugccaau aacaaacgac caaaaaaaac      780

uaaugucaaa uaacguacaa auaguaagac aacaaucaua cucaaucaug ugcauaauaa      840

aagaagaagu acuagccuau guaguccaau uaccacucua cggcguaauc gacaccccau      900

gcuggaaauu acacacaagc ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu      960

gcuuaaccag aaccgaucga ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc     1020

cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacacu augaacucac     1080

ucacacuucc aagcgaagua aaccuaugca acguagauau auuuaacccu aaauacgacu     1140

gcaaaauaau gacaagcaaa acagacguua guucaucagu aauuacaagu cuaggcgcaa     1200

uagugucaug cuacggaaaa acaaaaugca ccgcauccaa uaaaugccga ggaaucauua     1260

aaacauucuc aaacggaugc gacuacguca gcaauaaagg aguagacacu guuucuguag     1320

gaaacacccu auacuaugua aacaaacaag aaggucaauc acuauacgua aagggagaac     1380

caauuauaaa uuuuuacgac cccuuaguau uuccaaguga ugaauuugac gcaucuauaa     1440

gucaaguuaa cgaaaaaauu aaccaaucac uugcauuuau aagaaaauca gacgaacuac     1500

uccauaaugu aaacgcaggu aaaucaacaa caaacaucau gaucacaacc auaauaauag     1560

uaauaauugu aauauuacua ucacuaauag caguaggauu acuacucuac ugcaaagcua     1620

gaucuacccc ggucacacuc ucaaaagacc aauuaucugg aauaaacaau auagcauuca     1680

gcaacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7620
<211>  1951
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7620
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc caacgccaua accaccaucc      120

ucaccgccgu caccuucugc uucgcuucug gccaaaacau aaccgaagag uucuaccaau      180

ccacgugcuc ugccguguca aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu      240

ccgucaucac caucgaacuc ucuaacauca aagaaaucaa gugcaacggc acagacgcga      300

aagucaagcu caucaaacaa gaacuagaca aauacaaaaa cgccguaaca gaccuccaac      360

uccuaaugca guccacacca gccacaggcu ccggcagcgc caucgccucc ggcgucgcug      420

ucugcaaagu ccuacaccuc gaaggcgaag ucaacaaaau caagucagcc cuccuuagca      480

ccaacaaagc agucgucucu uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac      540

ucgaccucaa aaacuacauc gacaaacaac uacuaccaau acuaaacaaa cagagcugcu      600

ccauucccaa caucgaaacc guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucuccguc aacgcaggcg ucaccacccc agucuccacc uauaugcuaa      720

ccaacagcga acuccucagc cucaucaaug acaugccaau caccaacgac caaaagaaac      780

ucauguccaa caacguacag auaguccgcc agcaguccua cagcaucaug ugcaucauca      840

aagaagaagu gcucgccuac gugguacaac ucccucucua cggagucauu gauacacccu      900

gcuggaaacu ccacacaagc ccccucugca cuacaaacac caaagaaggc ucuaacauau      960

gccucacccg cacagaccgu gguugguacu gcgacaacgc cggcuccgua uccuucuuuc     1020

cacaagcuga aaccugcaaa guucaaucaa accgagucuu cugcgacacc augaacuccc     1080

ucacauugcc cagcgaaguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaaaaucau gaccuccaaa accgacguca gcuccagcgu gaucacaagc cuaggcgcga     1200

ucgucagcug cuacggcaaa accaaaugca cagccuccaa caaaugccgc ggaaucauaa     1260

aaacauucag uaacggcugc gacuacgugu ccaauaaagg agucgacacc guauccgucg     1320

gaaacacccu cuacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccauuaucaa cuucuacgac ccccuaguuu uccccuccga cgaguucgac gcaagcauuu     1440

cccaagucaa cgaaaagauc aaucaauccc ucgccuucau acgcaaaagc gacgaacuac     1500

uacacaacgu aaacgccggc aaaagcacca ccaacaucau gaucacaaca aucaucaucg     1560

ucaucaucgu cauccuacuc ucacucaucg ccguuggccu acuacucuac ugcaaagccc     1620

gcuccacacc cgucacccuc ucaaaagacc aacucuccgg caucaacaac aucgcauuca     1680

gcaacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga     1740

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua     1800

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1920

cccaaaggcu cuuuucagag ccaccagaau u                                    1951


<210>  7621
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7621
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7622
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7622
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccgguc cacccccgug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7623
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7623
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7624
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7624
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcuc aacacccgug     1680

acccugagua aagaucaacu cucuggaauc aauaacauug cuuucagcaa uugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7625
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7625
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7626
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7626
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaag cacacccgug     1680

acccuuucua aagaucaacu cuccggcauc aauaacaucg cguucagcaa uugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7627
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7627
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaac gcaaucacaa cuauacuaac agcaguaaca      180

uucugcuuug ccucagguca aaacauaaca gaggaauuuu accaauccac augcucugcu      240

guaagcaaag gauaccucgg agcauuaaga acuggauggu acaccucagu aauaacuaua      300

gaacuaucaa acauaaaaga aauaaaaugu aauggcacag acgcaaaagu gaaauuaauc      360

aaacaagaac ucgauaaaua caaaaaugcc guaaccgauc uccaacuuuu aaugcaaagc      420

acacccgcaa cagguuccgg gucagcaaua gcaagcggag uugcaguaug caaaguacua      480

cacuuagaag gagaaguaaa uaaaaucaaa ucagccuuac uaucaacaaa uaaagcaguu      540

guaucacucu caggaugcgg aguauccgua cuaacauuua aaguacuaga ucuaaaaaac      600

uacauagaua aacaacucuu accaauacua aauaaacaau cauguuccau acccaacaua      660

gaaaccguua ucgaauuuca acaaaaaaac aacagauuac uagaaaucac acgagaauuu      720

ucaguaaaug cuggagucac aacaccaguu aguacauaca ugcucaccaa uucagaacua      780

cuaaguuuaa uuaacgauau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      840

guacaaauag uaagacaaca aucauacuca aucaugugca uaauaaaaga agaaguacua      900

gccuauguag uccaauuacc acucuacggc guaaucgaca ccccaugcug gaaauuacac      960

acaagcccau uaugcaccac caacacaaaa gaagguucaa acauuugcuu aaccagaacc     1020

gaucgaggau gguacugcga uaacgcagga ucugucuccu uuuucccaca agccgaaaca     1080

ugcaaaguuc aaucaaaccg aguuuucugu gacacuauga acucacucac acuuccaagc     1140

gaaguaaacc uaugcaacgu agauauauuu aacccuaaau acgacugcaa aauaaugaca     1200

agcaaaacag acguuaguuc aucaguaauu acaagucuag gcgcaauagu gucaugcuac     1260

ggaaaaacaa aaugcaccgc auccaauaaa ugccgaggaa ucauuaaaac auucucaaac     1320

ggaugcgacu acgucagcaa uaaaggagua gacacuguuu cuguaggaaa cacccuauac     1380

uauguaaaca aacaagaagg ucaaucacua uacguaaagg gagaaccaau uauaaauuuu     1440

uacgaccccu uaguauuucc aagugaugaa uuugacgcau cuauaaguca aguuaacgaa     1500

aaaauuaacc aaucacuugc auuuauaaga aaaucagacg aacuacucca uaauguaaac     1560

gcagguaaau caacaacaaa caucaugauc acaaccauaa uaauaguaau aauuguaaua     1620

uuacuaucac uaauagcagu aggauuacua cucuacugca aagcuagauc uaccccgguc     1680

acacucucaa aagaccaauu aucuggaaua aacaauauag cauucagcaa cuaaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7628
<211>  2013
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7628
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagccaac gccauaacca ccauccucac cgccgucacc      180

uucugcuucg cuucuggcca aaacauaacc gaagaguucu accaauccac gugcucugcc      240

gugucaaaag gcuaccucgg agcccuccgc acaggguggu acacuuccgu caucaccauc      300

gaacucucua acaucaaaga aaucaagugc aacggcacag acgcgaaagu caagcucauc      360

aaacaagaac uagacaaaua caaaaacgcc guaacagacc uccaacuccu aaugcagucc      420

acaccagcca caggcuccgg cagcgccauc gccuccggcg ucgcugucug caaaguccua      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc uuagcaccaa caaagcaguc      540

gucucuuuaa gcgggugcgg agucucuguc cuaaccuuua aaguacucga ccucaaaaac      600

uacaucgaca aacaacuacu accaauacua aacaaacaga gcugcuccau ucccaacauc      660

gaaaccguua ucgaguucca acaaaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

uccgucaacg caggcgucac caccccaguc uccaccuaua ugcuaaccaa cagcgaacuc      780

cucagccuca ucaaugacau gccaaucacc aacgaccaaa agaaacucau guccaacaac      840

guacagauag uccgccagca guccuacagc aucaugugca ucaucaaaga agaagugcuc      900

gccuacgugg uacaacuccc ucucuacgga gucauugaua cacccugcug gaaacuccac      960

acaagccccc ucugcacuac aaacaccaaa gaaggcucua acauaugccu cacccgcaca     1020

gaccgugguu gguacugcga caacgccggc uccguauccu ucuuuccaca agcugaaacc     1080

ugcaaaguuc aaucaaaccg agucuucugc gacaccauga acucccucac auugcccagc     1140

gaagucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa aaucaugacc     1200

uccaaaaccg acgucagcuc cagcgugauc acaagccuag gcgcgaucgu cagcugcuac     1260

ggcaaaacca aaugcacagc cuccaacaaa ugccgcggaa ucauaaaaac auucaguaac     1320

ggcugcgacu acguguccaa uaaaggaguc gacaccguau ccgucggaaa cacccucuac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau uaucaacuuc     1440

uacgaccccc uaguuuuccc cuccgacgag uucgacgcaa gcauuuccca agucaacgaa     1500

aagaucaauc aaucccucgc cuucauacgc aaaagcgacg aacuacuaca caacguaaac     1560

gccggcaaaa gcaccaccaa caucaugauc acaacaauca ucaucgucau caucgucauc     1620

cuacucucac ucaucgccgu uggccuacua cucuacugca aagcccgcuc cacacccguc     1680

acccucucaa aagaccaacu cuccggcauc aacaacaucg cauucagcaa cugaggacua     1740

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg     1800

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1860

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1980

cccccaaagg cucuuuucag agccaccaga auu                                  2013


<210>  7629
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7629
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7630
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7630
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7631
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7631
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7632
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7632
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cucaacaccc gugacccuga guaaagauca acucucugga     1680

aucaauaaca uugcuuucag caauugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7633
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7633
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7634
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7634
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag aagcacaccc gugacccuuu cuaaagauca acucuccggc     1680

aucaauaaca ucgcguucag caauugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7635
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7635
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aacgcaauca caacuauacu aacagcagua acauucugcu uugccucagg ucaaaacaua      180

acagaggaau uuuaccaauc cacaugcucu gcuguaagca aaggauaccu cggagcauua      240

agaacuggau gguacaccuc aguaauaacu auagaacuau caaacauaaa agaaauaaaa      300

uguaauggca cagacgcaaa agugaaauua aucaaacaag aacucgauaa auacaaaaau      360

gccguaaccg aucuccaacu uuuaaugcaa agcacacccg caacagguuc cgggucagca      420

auagcaagcg gaguugcagu augcaaagua cuacacuuag aaggagaagu aaauaaaauc      480

aaaucagccu uacuaucaac aaauaaagca guuguaucac ucucaggaug cggaguaucc      540

guacuaacau uuaaaguacu agaucuaaaa aacuacauag auaaacaacu cuuaccaaua      600

cuaaauaaac aaucauguuc cauacccaac auagaaaccg uuaucgaauu ucaacaaaaa      660

aacaacagau uacuagaaau cacacgagaa uuuucaguaa augcuggagu cacaacacca      720

guuaguacau acaugcucac caauucagaa cuacuaaguu uaauuaacga uaugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaagua cuagccuaug uaguccaauu accacucuac      900

ggcguaaucg acaccccaug cuggaaauua cacacaagcc cauuaugcac caccaacaca      960

aaagaagguu caaacauuug cuuaaccaga accgaucgag gaugguacug cgauaacgca     1020

ggaucugucu ccuuuuuccc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacua ugaacucacu cacacuucca agcgaaguaa accuaugcaa cguagauaua     1140

uuuaacccua aauacgacug caaaauaaug acaagcaaaa cagacguuag uucaucagua     1200

auuacaaguc uaggcgcaau agugucaugc uacggaaaaa caaaaugcac cgcauccaau     1260

aaaugccgag gaaucauuaa aacauucuca aacggaugcg acuacgucag caauaaagga     1320

guagacacug uuucuguagg aaacacccua uacuauguaa acaaacaaga aggucaauca     1380

cuauacguaa agggagaacc aauuauaaau uuuuacgacc ccuuaguauu uccaagugau     1440

gaauuugacg caucuauaag ucaaguuaac gaaaaaauua accaaucacu ugcauuuaua     1500

agaaaaucag acgaacuacu ccauaaugua aacgcaggua aaucaacaac aaacaucaug     1560

aucacaacca uaauaauagu aauaauugua auauuacuau cacuaauagc aguaggauua     1620

cuacucuacu gcaaagcuag aucuaccccg gucacacucu caaaagacca auuaucugga     1680

auaaacaaua uagcauucag caacuaagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7636
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7636
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagcc      120

aacgccauaa ccaccauccu caccgccguc accuucugcu ucgcuucugg ccaaaacaua      180

accgaagagu ucuaccaauc cacgugcucu gccgugucaa aaggcuaccu cggagcccuc      240

cgcacagggu gguacacuuc cgucaucacc aucgaacucu cuaacaucaa agaaaucaag      300

ugcaacggca cagacgcgaa agucaagcuc aucaaacaag aacuagacaa auacaaaaac      360

gccguaacag accuccaacu ccuaaugcag uccacaccag ccacaggcuc cggcagcgcc      420

aucgccuccg gcgucgcugu cugcaaaguc cuacaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccuuagcac caacaaagca gucgucucuu uaagcgggug cggagucucu      540

guccuaaccu uuaaaguacu cgaccucaaa aacuacaucg acaaacaacu acuaccaaua      600

cuaaacaaac agagcugcuc cauucccaac aucgaaaccg uuaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccacccca      720

gucuccaccu auaugcuaac caacagcgaa cuccucagcc ucaucaauga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaga uaguccgcca gcaguccuac      840

agcaucaugu gcaucaucaa agaagaagug cucgccuacg ugguacaacu cccucucuac      900

ggagucauug auacacccug cuggaaacuc cacacaagcc cccucugcac uacaaacacc      960

aaagaaggcu cuaacauaug ccucacccgc acagaccgug guugguacug cgacaacgcc     1020

ggcuccguau ccuucuuucc acaagcugaa accugcaaag uucaaucaaa ccgagucuuc     1080

ugcgacacca ugaacucccu cacauugccc agcgaaguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caaaaucaug accuccaaaa ccgacgucag cuccagcgug     1200

aucacaagcc uaggcgcgau cgucagcugc uacggcaaaa ccaaaugcac agccuccaac     1260

aaaugccgcg gaaucauaaa aacauucagu aacggcugcg acuacguguc caauaaagga     1320

gucgacaccg uauccgucgg aaacacccuc uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc cauuaucaac uucuacgacc cccuaguuuu ccccuccgac     1440

gaguucgacg caagcauuuc ccaagucaac gaaaagauca aucaaucccu cgccuucaua     1500

cgcaaaagcg acgaacuacu acacaacgua aacgccggca aaagcaccac caacaucaug     1560

aucacaacaa ucaucaucgu caucaucguc auccuacucu cacucaucgc cguuggccua     1620

cuacucuacu gcaaagcccg cuccacaccc gucacccucu caaaagacca acucuccggc     1680

aucaacaaca ucgcauucag caacugagga cuagugucca ccugucccuc cugggcugcu     1740

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  7637
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7637
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7638
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7638
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccgguc cacccccgug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7639
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7639
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7640
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7640
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcuc aacacccgug     1680

acccugagua aagaucaacu cucuggaauc aauaacauug cuuucagcaa uugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7641
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7641
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7642
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7642
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaag cacacccgug     1680

acccuuucua aagaucaacu cuccggcauc aauaacaucg cguucagcaa uugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7643
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7643
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaac gcaaucacaa cuauacuaac agcaguaaca      180

uucugcuuug ccucagguca aaacauaaca gaggaauuuu accaauccac augcucugcu      240

guaagcaaag gauaccucgg agcauuaaga acuggauggu acaccucagu aauaacuaua      300

gaacuaucaa acauaaaaga aauaaaaugu aauggcacag acgcaaaagu gaaauuaauc      360

aaacaagaac ucgauaaaua caaaaaugcc guaaccgauc uccaacuuuu aaugcaaagc      420

acacccgcaa cagguuccgg gucagcaaua gcaagcggag uugcaguaug caaaguacua      480

cacuuagaag gagaaguaaa uaaaaucaaa ucagccuuac uaucaacaaa uaaagcaguu      540

guaucacucu caggaugcgg aguauccgua cuaacauuua aaguacuaga ucuaaaaaac      600

uacauagaua aacaacucuu accaauacua aauaaacaau cauguuccau acccaacaua      660

gaaaccguua ucgaauuuca acaaaaaaac aacagauuac uagaaaucac acgagaauuu      720

ucaguaaaug cuggagucac aacaccaguu aguacauaca ugcucaccaa uucagaacua      780

cuaaguuuaa uuaacgauau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      840

guacaaauag uaagacaaca aucauacuca aucaugugca uaauaaaaga agaaguacua      900

gccuauguag uccaauuacc acucuacggc guaaucgaca ccccaugcug gaaauuacac      960

acaagcccau uaugcaccac caacacaaaa gaagguucaa acauuugcuu aaccagaacc     1020

gaucgaggau gguacugcga uaacgcagga ucugucuccu uuuucccaca agccgaaaca     1080

ugcaaaguuc aaucaaaccg aguuuucugu gacacuauga acucacucac acuuccaagc     1140

gaaguaaacc uaugcaacgu agauauauuu aacccuaaau acgacugcaa aauaaugaca     1200

agcaaaacag acguuaguuc aucaguaauu acaagucuag gcgcaauagu gucaugcuac     1260

ggaaaaacaa aaugcaccgc auccaauaaa ugccgaggaa ucauuaaaac auucucaaac     1320

ggaugcgacu acgucagcaa uaaaggagua gacacuguuu cuguaggaaa cacccuauac     1380

uauguaaaca aacaagaagg ucaaucacua uacguaaagg gagaaccaau uauaaauuuu     1440

uacgaccccu uaguauuucc aagugaugaa uuugacgcau cuauaaguca aguuaacgaa     1500

aaaauuaacc aaucacuugc auuuauaaga aaaucagacg aacuacucca uaauguaaac     1560

gcagguaaau caacaacaaa caucaugauc acaaccauaa uaauaguaau aauuguaaua     1620

uuacuaucac uaauagcagu aggauuacua cucuacugca aagcuagauc uaccccgguc     1680

acacucucaa aagaccaauu aucuggaaua aacaauauag cauucagcaa cuaaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7644
<211>  2009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7644
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagccaac gccauaacca ccauccucac cgccgucacc      180

uucugcuucg cuucuggcca aaacauaacc gaagaguucu accaauccac gugcucugcc      240

gugucaaaag gcuaccucgg agcccuccgc acaggguggu acacuuccgu caucaccauc      300

gaacucucua acaucaaaga aaucaagugc aacggcacag acgcgaaagu caagcucauc      360

aaacaagaac uagacaaaua caaaaacgcc guaacagacc uccaacuccu aaugcagucc      420

acaccagcca caggcuccgg cagcgccauc gccuccggcg ucgcugucug caaaguccua      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc uuagcaccaa caaagcaguc      540

gucucuuuaa gcgggugcgg agucucuguc cuaaccuuua aaguacucga ccucaaaaac      600

uacaucgaca aacaacuacu accaauacua aacaaacaga gcugcuccau ucccaacauc      660

gaaaccguua ucgaguucca acaaaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

uccgucaacg caggcgucac caccccaguc uccaccuaua ugcuaaccaa cagcgaacuc      780

cucagccuca ucaaugacau gccaaucacc aacgaccaaa agaaacucau guccaacaac      840

guacagauag uccgccagca guccuacagc aucaugugca ucaucaaaga agaagugcuc      900

gccuacgugg uacaacuccc ucucuacgga gucauugaua cacccugcug gaaacuccac      960

acaagccccc ucugcacuac aaacaccaaa gaaggcucua acauaugccu cacccgcaca     1020

gaccgugguu gguacugcga caacgccggc uccguauccu ucuuuccaca agcugaaacc     1080

ugcaaaguuc aaucaaaccg agucuucugc gacaccauga acucccucac auugcccagc     1140

gaagucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa aaucaugacc     1200

uccaaaaccg acgucagcuc cagcgugauc acaagccuag gcgcgaucgu cagcugcuac     1260

ggcaaaacca aaugcacagc cuccaacaaa ugccgcggaa ucauaaaaac auucaguaac     1320

ggcugcgacu acguguccaa uaaaggaguc gacaccguau ccgucggaaa cacccucuac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau uaucaacuuc     1440

uacgaccccc uaguuuuccc cuccgacgag uucgacgcaa gcauuuccca agucaacgaa     1500

aagaucaauc aaucccucgc cuucauacgc aaaagcgacg aacuacuaca caacguaaac     1560

gccggcaaaa gcaccaccaa caucaugauc acaacaauca ucaucgucau caucgucauc     1620

cuacucucac ucaucgccgu uggccuacua cucuacugca aagcccgcuc cacacccguc     1680

acccucucaa aagaccaacu cuccggcauc aacaacaucg cauucagcaa cugaggacua     1740

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu     1800

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1860

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1980

caaaggcucu uuucagagcc accagaauu                                       2009


<210>  7645
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7645
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7646
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7646
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7647
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7647
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7648
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7648
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cucaacaccc gugacccuga guaaagauca acucucugga     1680

aucaauaaca uugcuuucag caauugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7649
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7649
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7650
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7650
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag aagcacaccc gugacccuuu cuaaagauca acucuccggc     1680

aucaauaaca ucgcguucag caauugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7651
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7651
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aacgcaauca caacuauacu aacagcagua acauucugcu uugccucagg ucaaaacaua      180

acagaggaau uuuaccaauc cacaugcucu gcuguaagca aaggauaccu cggagcauua      240

agaacuggau gguacaccuc aguaauaacu auagaacuau caaacauaaa agaaauaaaa      300

uguaauggca cagacgcaaa agugaaauua aucaaacaag aacucgauaa auacaaaaau      360

gccguaaccg aucuccaacu uuuaaugcaa agcacacccg caacagguuc cgggucagca      420

auagcaagcg gaguugcagu augcaaagua cuacacuuag aaggagaagu aaauaaaauc      480

aaaucagccu uacuaucaac aaauaaagca guuguaucac ucucaggaug cggaguaucc      540

guacuaacau uuaaaguacu agaucuaaaa aacuacauag auaaacaacu cuuaccaaua      600

cuaaauaaac aaucauguuc cauacccaac auagaaaccg uuaucgaauu ucaacaaaaa      660

aacaacagau uacuagaaau cacacgagaa uuuucaguaa augcuggagu cacaacacca      720

guuaguacau acaugcucac caauucagaa cuacuaaguu uaauuaacga uaugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaagua cuagccuaug uaguccaauu accacucuac      900

ggcguaaucg acaccccaug cuggaaauua cacacaagcc cauuaugcac caccaacaca      960

aaagaagguu caaacauuug cuuaaccaga accgaucgag gaugguacug cgauaacgca     1020

ggaucugucu ccuuuuuccc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacua ugaacucacu cacacuucca agcgaaguaa accuaugcaa cguagauaua     1140

uuuaacccua aauacgacug caaaauaaug acaagcaaaa cagacguuag uucaucagua     1200

auuacaaguc uaggcgcaau agugucaugc uacggaaaaa caaaaugcac cgcauccaau     1260

aaaugccgag gaaucauuaa aacauucuca aacggaugcg acuacgucag caauaaagga     1320

guagacacug uuucuguagg aaacacccua uacuauguaa acaaacaaga aggucaauca     1380

cuauacguaa agggagaacc aauuauaaau uuuuacgacc ccuuaguauu uccaagugau     1440

gaauuugacg caucuauaag ucaaguuaac gaaaaaauua accaaucacu ugcauuuaua     1500

agaaaaucag acgaacuacu ccauaaugua aacgcaggua aaucaacaac aaacaucaug     1560

aucacaacca uaauaauagu aauaauugua auauuacuau cacuaauagc aguaggauua     1620

cuacucuacu gcaaagcuag aucuaccccg gucacacucu caaaagacca auuaucugga     1680

auaaacaaua uagcauucag caacuaagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7652
<211>  1986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7652
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagcc      120

aacgccauaa ccaccauccu caccgccguc accuucugcu ucgcuucugg ccaaaacaua      180

accgaagagu ucuaccaauc cacgugcucu gccgugucaa aaggcuaccu cggagcccuc      240

cgcacagggu gguacacuuc cgucaucacc aucgaacucu cuaacaucaa agaaaucaag      300

ugcaacggca cagacgcgaa agucaagcuc aucaaacaag aacuagacaa auacaaaaac      360

gccguaacag accuccaacu ccuaaugcag uccacaccag ccacaggcuc cggcagcgcc      420

aucgccuccg gcgucgcugu cugcaaaguc cuacaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccuuagcac caacaaagca gucgucucuu uaagcgggug cggagucucu      540

guccuaaccu uuaaaguacu cgaccucaaa aacuacaucg acaaacaacu acuaccaaua      600

cuaaacaaac agagcugcuc cauucccaac aucgaaaccg uuaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccacccca      720

gucuccaccu auaugcuaac caacagcgaa cuccucagcc ucaucaauga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaga uaguccgcca gcaguccuac      840

agcaucaugu gcaucaucaa agaagaagug cucgccuacg ugguacaacu cccucucuac      900

ggagucauug auacacccug cuggaaacuc cacacaagcc cccucugcac uacaaacacc      960

aaagaaggcu cuaacauaug ccucacccgc acagaccgug guugguacug cgacaacgcc     1020

ggcuccguau ccuucuuucc acaagcugaa accugcaaag uucaaucaaa ccgagucuuc     1080

ugcgacacca ugaacucccu cacauugccc agcgaaguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caaaaucaug accuccaaaa ccgacgucag cuccagcgug     1200

aucacaagcc uaggcgcgau cgucagcugc uacggcaaaa ccaaaugcac agccuccaac     1260

aaaugccgcg gaaucauaaa aacauucagu aacggcugcg acuacguguc caauaaagga     1320

gucgacaccg uauccgucgg aaacacccuc uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc cauuaucaac uucuacgacc cccuaguuuu ccccuccgac     1440

gaguucgacg caagcauuuc ccaagucaac gaaaagauca aucaaucccu cgccuucaua     1500

cgcaaaagcg acgaacuacu acacaacgua aacgccggca aaagcaccac caacaucaug     1560

aucacaacaa ucaucaucgu caucaucguc auccuacucu cacucaucgc cguuggccua     1620

cuacucuacu gcaaagcccg cuccacaccc gucacccucu caaaagacca acucuccggc     1680

aucaacaaca ucgcauucag caacugagga cuaguacugg cugcaucucc cuuuccucug     1740

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1800

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1980

agaauu                                                                1986


<210>  7653
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7653
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7654
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7654
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7655
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7655
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7656
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7656
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cucaacaccc gugacccuga guaaagauca acucucugga     1680

aucaauaaca uugcuuucag caauugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7657
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7657
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7658
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7658
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag aagcacaccc gugacccuuu cuaaagauca acucuccggc     1680

aucaauaaca ucgcguucag caauugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7659
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7659
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aacgcaauca caacuauacu aacagcagua acauucugcu uugccucagg ucaaaacaua      180

acagaggaau uuuaccaauc cacaugcucu gcuguaagca aaggauaccu cggagcauua      240

agaacuggau gguacaccuc aguaauaacu auagaacuau caaacauaaa agaaauaaaa      300

uguaauggca cagacgcaaa agugaaauua aucaaacaag aacucgauaa auacaaaaau      360

gccguaaccg aucuccaacu uuuaaugcaa agcacacccg caacagguuc cgggucagca      420

auagcaagcg gaguugcagu augcaaagua cuacacuuag aaggagaagu aaauaaaauc      480

aaaucagccu uacuaucaac aaauaaagca guuguaucac ucucaggaug cggaguaucc      540

guacuaacau uuaaaguacu agaucuaaaa aacuacauag auaaacaacu cuuaccaaua      600

cuaaauaaac aaucauguuc cauacccaac auagaaaccg uuaucgaauu ucaacaaaaa      660

aacaacagau uacuagaaau cacacgagaa uuuucaguaa augcuggagu cacaacacca      720

guuaguacau acaugcucac caauucagaa cuacuaaguu uaauuaacga uaugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaagua cuagccuaug uaguccaauu accacucuac      900

ggcguaaucg acaccccaug cuggaaauua cacacaagcc cauuaugcac caccaacaca      960

aaagaagguu caaacauuug cuuaaccaga accgaucgag gaugguacug cgauaacgca     1020

ggaucugucu ccuuuuuccc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacua ugaacucacu cacacuucca agcgaaguaa accuaugcaa cguagauaua     1140

uuuaacccua aauacgacug caaaauaaug acaagcaaaa cagacguuag uucaucagua     1200

auuacaaguc uaggcgcaau agugucaugc uacggaaaaa caaaaugcac cgcauccaau     1260

aaaugccgag gaaucauuaa aacauucuca aacggaugcg acuacgucag caauaaagga     1320

guagacacug uuucuguagg aaacacccua uacuauguaa acaaacaaga aggucaauca     1380

cuauacguaa agggagaacc aauuauaaau uuuuacgacc ccuuaguauu uccaagugau     1440

gaauuugacg caucuauaag ucaaguuaac gaaaaaauua accaaucacu ugcauuuaua     1500

agaaaaucag acgaacuacu ccauaaugua aacgcaggua aaucaacaac aaacaucaug     1560

aucacaacca uaauaauagu aauaauugua auauuacuau cacuaauagc aguaggauua     1620

cuacucuacu gcaaagcuag aucuaccccg gucacacucu caaaagacca auuaucugga     1680

auaaacaaua uagcauucag caacuaagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7660
<211>  1982
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7660
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagcc      120

aacgccauaa ccaccauccu caccgccguc accuucugcu ucgcuucugg ccaaaacaua      180

accgaagagu ucuaccaauc cacgugcucu gccgugucaa aaggcuaccu cggagcccuc      240

cgcacagggu gguacacuuc cgucaucacc aucgaacucu cuaacaucaa agaaaucaag      300

ugcaacggca cagacgcgaa agucaagcuc aucaaacaag aacuagacaa auacaaaaac      360

gccguaacag accuccaacu ccuaaugcag uccacaccag ccacaggcuc cggcagcgcc      420

aucgccuccg gcgucgcugu cugcaaaguc cuacaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccuuagcac caacaaagca gucgucucuu uaagcgggug cggagucucu      540

guccuaaccu uuaaaguacu cgaccucaaa aacuacaucg acaaacaacu acuaccaaua      600

cuaaacaaac agagcugcuc cauucccaac aucgaaaccg uuaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccacccca      720

gucuccaccu auaugcuaac caacagcgaa cuccucagcc ucaucaauga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaga uaguccgcca gcaguccuac      840

agcaucaugu gcaucaucaa agaagaagug cucgccuacg ugguacaacu cccucucuac      900

ggagucauug auacacccug cuggaaacuc cacacaagcc cccucugcac uacaaacacc      960

aaagaaggcu cuaacauaug ccucacccgc acagaccgug guugguacug cgacaacgcc     1020

ggcuccguau ccuucuuucc acaagcugaa accugcaaag uucaaucaaa ccgagucuuc     1080

ugcgacacca ugaacucccu cacauugccc agcgaaguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caaaaucaug accuccaaaa ccgacgucag cuccagcgug     1200

aucacaagcc uaggcgcgau cgucagcugc uacggcaaaa ccaaaugcac agccuccaac     1260

aaaugccgcg gaaucauaaa aacauucagu aacggcugcg acuacguguc caauaaagga     1320

gucgacaccg uauccgucgg aaacacccuc uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc cauuaucaac uucuacgacc cccuaguuuu ccccuccgac     1440

gaguucgacg caagcauuuc ccaagucaac gaaaagauca aucaaucccu cgccuucaua     1500

cgcaaaagcg acgaacuacu acacaacgua aacgccggca aaagcaccac caacaucaug     1560

aucacaacaa ucaucaucgu caucaucguc auccuacucu cacucaucgc cguuggccua     1620

cuacucuacu gcaaagcccg cuccacaccc gucacccucu caaaagacca acucuccggc     1680

aucaacaaca ucgcauucag caacugagga cuaguggaag cauuuuccug gcugauuaaa     1740

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1800

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1920

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1980

uu                                                                    1982


<210>  7661
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7661
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7662
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7662
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccgguccac ccccgugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7663
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7663
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7664
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7664
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcucaac acccgugacc cugaguaaag aucaacucuc uggaaucaau     1680

aacauugcuu ucagcaauug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7665
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7665
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7666
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7666
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaagcac acccgugacc cuuucuaaag aucaacucuc cggcaucaau     1680

aacaucgcgu ucagcaauug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7667
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7667
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaacgca      120

aucacaacua uacuaacagc aguaacauuc ugcuuugccu caggucaaaa cauaacagag      180

gaauuuuacc aauccacaug cucugcugua agcaaaggau accucggagc auuaagaacu      240

ggaugguaca ccucaguaau aacuauagaa cuaucaaaca uaaaagaaau aaaauguaau      300

ggcacagacg caaaagugaa auuaaucaaa caagaacucg auaaauacaa aaaugccgua      360

accgaucucc aacuuuuaau gcaaagcaca cccgcaacag guuccggguc agcaauagca      420

agcggaguug caguaugcaa aguacuacac uuagaaggag aaguaaauaa aaucaaauca      480

gccuuacuau caacaaauaa agcaguugua ucacucucag gaugcggagu auccguacua      540

acauuuaaag uacuagaucu aaaaaacuac auagauaaac aacucuuacc aauacuaaau      600

aaacaaucau guuccauacc caacauagaa accguuaucg aauuucaaca aaaaaacaac      660

agauuacuag aaaucacacg agaauuuuca guaaaugcug gagucacaac accaguuagu      720

acauacaugc ucaccaauuc agaacuacua aguuuaauua acgauaugcc aauaacaaac      780

gaccaaaaaa aacuaauguc aaauaacgua caaauaguaa gacaacaauc auacucaauc      840

augugcauaa uaaaagaaga aguacuagcc uauguagucc aauuaccacu cuacggcgua      900

aucgacaccc caugcuggaa auuacacaca agcccauuau gcaccaccaa cacaaaagaa      960

gguucaaaca uuugcuuaac cagaaccgau cgaggauggu acugcgauaa cgcaggaucu     1020

gucuccuuuu ucccacaagc cgaaacaugc aaaguucaau caaaccgagu uuucugugac     1080

acuaugaacu cacucacacu uccaagcgaa guaaaccuau gcaacguaga uauauuuaac     1140

ccuaaauacg acugcaaaau aaugacaagc aaaacagacg uuaguucauc aguaauuaca     1200

agucuaggcg caauaguguc augcuacgga aaaacaaaau gcaccgcauc caauaaaugc     1260

cgaggaauca uuaaaacauu cucaaacgga ugcgacuacg ucagcaauaa aggaguagac     1320

acuguuucug uaggaaacac ccuauacuau guaaacaaac aagaagguca aucacuauac     1380

guaaagggag aaccaauuau aaauuuuuac gaccccuuag uauuuccaag ugaugaauuu     1440

gacgcaucua uaagucaagu uaacgaaaaa auuaaccaau cacuugcauu uauaagaaaa     1500

ucagacgaac uacuccauaa uguaaacgca gguaaaucaa caacaaacau caugaucaca     1560

accauaauaa uaguaauaau uguaauauua cuaucacuaa uagcaguagg auuacuacuc     1620

uacugcaaag cuagaucuac cccggucaca cucucaaaag accaauuauc uggaauaaac     1680

aauauagcau ucagcaacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7668
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7668
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agccaacgcc      120

auaaccacca uccucaccgc cgucaccuuc ugcuucgcuu cuggccaaaa cauaaccgaa      180

gaguucuacc aauccacgug cucugccgug ucaaaaggcu accucggagc ccuccgcaca      240

gggugguaca cuuccgucau caccaucgaa cucucuaaca ucaaagaaau caagugcaac      300

ggcacagacg cgaaagucaa gcucaucaaa caagaacuag acaaauacaa aaacgccgua      360

acagaccucc aacuccuaau gcaguccaca ccagccacag gcuccggcag cgccaucgcc      420

uccggcgucg cugucugcaa aguccuacac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccuua gcaccaacaa agcagucguc ucuuuaagcg ggugcggagu cucuguccua      540

accuuuaaag uacucgaccu caaaaacuac aucgacaaac aacuacuacc aauacuaaac      600

aaacagagcu gcuccauucc caacaucgaa accguuaucg aguuccaaca aaagaacaac      660

cgccuccucg aaaucacccg cgaguucucc gucaacgcag gcgucaccac cccagucucc      720

accuauaugc uaaccaacag cgaacuccuc agccucauca augacaugcc aaucaccaac      780

gaccaaaaga aacucauguc caacaacgua cagauagucc gccagcaguc cuacagcauc      840

augugcauca ucaaagaaga agugcucgcc uacgugguac aacucccucu cuacggaguc      900

auugauacac ccugcuggaa acuccacaca agcccccucu gcacuacaaa caccaaagaa      960

ggcucuaaca uaugccucac ccgcacagac cgugguuggu acugcgacaa cgccggcucc     1020

guauccuucu uuccacaagc ugaaaccugc aaaguucaau caaaccgagu cuucugcgac     1080

accaugaacu cccucacauu gcccagcgaa gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaaaau caugaccucc aaaaccgacg ucagcuccag cgugaucaca     1200

agccuaggcg cgaucgucag cugcuacggc aaaaccaaau gcacagccuc caacaaaugc     1260

cgcggaauca uaaaaacauu caguaacggc ugcgacuacg uguccaauaa aggagucgac     1320

accguauccg ucggaaacac ccucuacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccauuau caacuucuac gacccccuag uuuuccccuc cgacgaguuc     1440

gacgcaagca uuucccaagu caacgaaaag aucaaucaau cccucgccuu cauacgcaaa     1500

agcgacgaac uacuacacaa cguaaacgcc ggcaaaagca ccaccaacau caugaucaca     1560

acaaucauca ucgucaucau cgucauccua cucucacuca ucgccguugg ccuacuacuc     1620

uacugcaaag cccgcuccac acccgucacc cucucaaaag accaacucuc cggcaucaac     1680

aacaucgcau ucagcaacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu     1740

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  7669
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7669
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7670
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7670
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccgguccacc cccgugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7671
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7671
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7672
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7672
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcucaaca cccgugaccc ugaguaaaga ucaacucucu     1680

ggaaucaaua acauugcuuu cagcaauuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7673
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7673
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7674
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7674
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaagcaca cccgugaccc uuucuaaaga ucaacucucc     1680

ggcaucaaua acaucgcguu cagcaauuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7675
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7675
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaacgcaa ucacaacuau acuaacagca guaacauucu gcuuugccuc aggucaaaac      180

auaacagagg aauuuuacca auccacaugc ucugcuguaa gcaaaggaua ccucggagca      240

uuaagaacug gaugguacac cucaguaaua acuauagaac uaucaaacau aaaagaaaua      300

aaauguaaug gcacagacgc aaaagugaaa uuaaucaaac aagaacucga uaaauacaaa      360

aaugccguaa ccgaucucca acuuuuaaug caaagcacac ccgcaacagg uuccggguca      420

gcaauagcaa gcggaguugc aguaugcaaa guacuacacu uagaaggaga aguaaauaaa      480

aucaaaucag ccuuacuauc aacaaauaaa gcaguuguau cacucucagg augcggagua      540

uccguacuaa cauuuaaagu acuagaucua aaaaacuaca uagauaaaca acucuuacca      600

auacuaaaua aacaaucaug uuccauaccc aacauagaaa ccguuaucga auuucaacaa      660

aaaaacaaca gauuacuaga aaucacacga gaauuuucag uaaaugcugg agucacaaca      720

ccaguuagua cauacaugcu caccaauuca gaacuacuaa guuuaauuaa cgauaugcca      780

auaacaaacg accaaaaaaa acuaauguca aauaacguac aaauaguaag acaacaauca      840

uacucaauca ugugcauaau aaaagaagaa guacuagccu auguagucca auuaccacuc      900

uacggcguaa ucgacacccc augcuggaaa uuacacacaa gcccauuaug caccaccaac      960

acaaaagaag guucaaacau uugcuuaacc agaaccgauc gaggauggua cugcgauaac     1020

gcaggaucug ucuccuuuuu cccacaagcc gaaacaugca aaguucaauc aaaccgaguu     1080

uucugugaca cuaugaacuc acucacacuu ccaagcgaag uaaaccuaug caacguagau     1140

auauuuaacc cuaaauacga cugcaaaaua augacaagca aaacagacgu uaguucauca     1200

guaauuacaa gucuaggcgc aauaguguca ugcuacggaa aaacaaaaug caccgcaucc     1260

aauaaaugcc gaggaaucau uaaaacauuc ucaaacggau gcgacuacgu cagcaauaaa     1320

ggaguagaca cuguuucugu aggaaacacc cuauacuaug uaaacaaaca agaaggucaa     1380

ucacuauacg uaaagggaga accaauuaua aauuuuuacg accccuuagu auuuccaagu     1440

gaugaauuug acgcaucuau aagucaaguu aacgaaaaaa uuaaccaauc acuugcauuu     1500

auaagaaaau cagacgaacu acuccauaau guaaacgcag guaaaucaac aacaaacauc     1560

augaucacaa ccauaauaau aguaauaauu guaauauuac uaucacuaau agcaguagga     1620

uuacuacucu acugcaaagc uagaucuacc ccggucacac ucucaaaaga ccaauuaucu     1680

ggaauaaaca auauagcauu cagcaacuaa ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7676
<211>  1909
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7676
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gccaacgcca uaaccaccau ccucaccgcc gucaccuucu gcuucgcuuc uggccaaaac      180

auaaccgaag aguucuacca auccacgugc ucugccgugu caaaaggcua ccucggagcc      240

cuccgcacag ggugguacac uuccgucauc accaucgaac ucucuaacau caaagaaauc      300

aagugcaacg gcacagacgc gaaagucaag cucaucaaac aagaacuaga caaauacaaa      360

aacgccguaa cagaccucca acuccuaaug caguccacac cagccacagg cuccggcagc      420

gccaucgccu ccggcgucgc ugucugcaaa guccuacacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccuuag caccaacaaa gcagucgucu cuuuaagcgg gugcggaguc      540

ucuguccuaa ccuuuaaagu acucgaccuc aaaaacuaca ucgacaaaca acuacuacca      600

auacuaaaca aacagagcug cuccauuccc aacaucgaaa ccguuaucga guuccaacaa      660

aagaacaacc gccuccucga aaucacccgc gaguucuccg ucaacgcagg cgucaccacc      720

ccagucucca ccuauaugcu aaccaacagc gaacuccuca gccucaucaa ugacaugcca      780

aucaccaacg accaaaagaa acucaugucc aacaacguac agauaguccg ccagcagucc      840

uacagcauca ugugcaucau caaagaagaa gugcucgccu acgugguaca acucccucuc      900

uacggaguca uugauacacc cugcuggaaa cuccacacaa gcccccucug cacuacaaac      960

accaaagaag gcucuaacau augccucacc cgcacagacc gugguuggua cugcgacaac     1020

gccggcuccg uauccuucuu uccacaagcu gaaaccugca aaguucaauc aaaccgaguc     1080

uucugcgaca ccaugaacuc ccucacauug cccagcgaag ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaaaauc augaccucca aaaccgacgu cagcuccagc     1200

gugaucacaa gccuaggcgc gaucgucagc ugcuacggca aaaccaaaug cacagccucc     1260

aacaaaugcc gcggaaucau aaaaacauuc aguaacggcu gcgacuacgu guccaauaaa     1320

ggagucgaca ccguauccgu cggaaacacc cucuacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccauuauc aacuucuacg acccccuagu uuuccccucc     1440

gacgaguucg acgcaagcau uucccaaguc aacgaaaaga ucaaucaauc ccucgccuuc     1500

auacgcaaaa gcgacgaacu acuacacaac guaaacgccg gcaaaagcac caccaacauc     1560

augaucacaa caaucaucau cgucaucauc gucauccuac ucucacucau cgccguuggc     1620

cuacuacucu acugcaaagc ccgcuccaca cccgucaccc ucucaaaaga ccaacucucc     1680

ggcaucaaca acaucgcauu cagcaacuga ggacuagucc cuguucccag agcccacuuu     1740

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1860

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1909


<210>  7677
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7677
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7678
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7678
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccgguccac ccccgugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7679
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7679
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7680
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7680
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcucaac acccgugacc cugaguaaag aucaacucuc uggaaucaau     1680

aacauugcuu ucagcaauug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7681
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7681
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7682
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7682
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaagcac acccgugacc cuuucuaaag aucaacucuc cggcaucaau     1680

aacaucgcgu ucagcaauug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7683
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7683
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaacgca      120

aucacaacua uacuaacagc aguaacauuc ugcuuugccu caggucaaaa cauaacagag      180

gaauuuuacc aauccacaug cucugcugua agcaaaggau accucggagc auuaagaacu      240

ggaugguaca ccucaguaau aacuauagaa cuaucaaaca uaaaagaaau aaaauguaau      300

ggcacagacg caaaagugaa auuaaucaaa caagaacucg auaaauacaa aaaugccgua      360

accgaucucc aacuuuuaau gcaaagcaca cccgcaacag guuccggguc agcaauagca      420

agcggaguug caguaugcaa aguacuacac uuagaaggag aaguaaauaa aaucaaauca      480

gccuuacuau caacaaauaa agcaguugua ucacucucag gaugcggagu auccguacua      540

acauuuaaag uacuagaucu aaaaaacuac auagauaaac aacucuuacc aauacuaaau      600

aaacaaucau guuccauacc caacauagaa accguuaucg aauuucaaca aaaaaacaac      660

agauuacuag aaaucacacg agaauuuuca guaaaugcug gagucacaac accaguuagu      720

acauacaugc ucaccaauuc agaacuacua aguuuaauua acgauaugcc aauaacaaac      780

gaccaaaaaa aacuaauguc aaauaacgua caaauaguaa gacaacaauc auacucaauc      840

augugcauaa uaaaagaaga aguacuagcc uauguagucc aauuaccacu cuacggcgua      900

aucgacaccc caugcuggaa auuacacaca agcccauuau gcaccaccaa cacaaaagaa      960

gguucaaaca uuugcuuaac cagaaccgau cgaggauggu acugcgauaa cgcaggaucu     1020

gucuccuuuu ucccacaagc cgaaacaugc aaaguucaau caaaccgagu uuucugugac     1080

acuaugaacu cacucacacu uccaagcgaa guaaaccuau gcaacguaga uauauuuaac     1140

ccuaaauacg acugcaaaau aaugacaagc aaaacagacg uuaguucauc aguaauuaca     1200

agucuaggcg caauaguguc augcuacgga aaaacaaaau gcaccgcauc caauaaaugc     1260

cgaggaauca uuaaaacauu cucaaacgga ugcgacuacg ucagcaauaa aggaguagac     1320

acuguuucug uaggaaacac ccuauacuau guaaacaaac aagaagguca aucacuauac     1380

guaaagggag aaccaauuau aaauuuuuac gaccccuuag uauuuccaag ugaugaauuu     1440

gacgcaucua uaagucaagu uaacgaaaaa auuaaccaau cacuugcauu uauaagaaaa     1500

ucagacgaac uacuccauaa uguaaacgca gguaaaucaa caacaaacau caugaucaca     1560

accauaauaa uaguaauaau uguaauauua cuaucacuaa uagcaguagg auuacuacuc     1620

uacugcaaag cuagaucuac cccggucaca cucucaaaag accaauuauc uggaauaaac     1680

aauauagcau ucagcaacua aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7684
<211>  1964
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7684
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agccaacgcc      120

auaaccacca uccucaccgc cgucaccuuc ugcuucgcuu cuggccaaaa cauaaccgaa      180

gaguucuacc aauccacgug cucugccgug ucaaaaggcu accucggagc ccuccgcaca      240

gggugguaca cuuccgucau caccaucgaa cucucuaaca ucaaagaaau caagugcaac      300

ggcacagacg cgaaagucaa gcucaucaaa caagaacuag acaaauacaa aaacgccgua      360

acagaccucc aacuccuaau gcaguccaca ccagccacag gcuccggcag cgccaucgcc      420

uccggcgucg cugucugcaa aguccuacac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccuua gcaccaacaa agcagucguc ucuuuaagcg ggugcggagu cucuguccua      540

accuuuaaag uacucgaccu caaaaacuac aucgacaaac aacuacuacc aauacuaaac      600

aaacagagcu gcuccauucc caacaucgaa accguuaucg aguuccaaca aaagaacaac      660

cgccuccucg aaaucacccg cgaguucucc gucaacgcag gcgucaccac cccagucucc      720

accuauaugc uaaccaacag cgaacuccuc agccucauca augacaugcc aaucaccaac      780

gaccaaaaga aacucauguc caacaacgua cagauagucc gccagcaguc cuacagcauc      840

augugcauca ucaaagaaga agugcucgcc uacgugguac aacucccucu cuacggaguc      900

auugauacac ccugcuggaa acuccacaca agcccccucu gcacuacaaa caccaaagaa      960

ggcucuaaca uaugccucac ccgcacagac cgugguuggu acugcgacaa cgccggcucc     1020

guauccuucu uuccacaagc ugaaaccugc aaaguucaau caaaccgagu cuucugcgac     1080

accaugaacu cccucacauu gcccagcgaa gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaaaau caugaccucc aaaaccgacg ucagcuccag cgugaucaca     1200

agccuaggcg cgaucgucag cugcuacggc aaaaccaaau gcacagccuc caacaaaugc     1260

cgcggaauca uaaaaacauu caguaacggc ugcgacuacg uguccaauaa aggagucgac     1320

accguauccg ucggaaacac ccucuacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccauuau caacuucuac gacccccuag uuuuccccuc cgacgaguuc     1440

gacgcaagca uuucccaagu caacgaaaag aucaaucaau cccucgccuu cauacgcaaa     1500

agcgacgaac uacuacacaa cguaaacgcc ggcaaaagca ccaccaacau caugaucaca     1560

acaaucauca ucgucaucau cgucauccua cucucacuca ucgccguugg ccuacuacuc     1620

uacugcaaag cccgcuccac acccgucacc cucucaaaag accaacucuc cggcaucaac     1680

aacaucgcau ucagcaacug aggacuagua auaaggaaac uguaugaaug ucugugggca     1740

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu     1800

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1920

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1964


<210>  7685
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7685
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7686
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7686
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7687
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7687
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7688
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7688
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu caacacccgu gacccugagu     1740

aaagaucaac ucucuggaau caauaacauu gcuuucagca auugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7689
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7689
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7690
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7690
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagaa gcacacccgu gacccuuucu     1740

aaagaucaac ucuccggcau caauaacauc gcguucagca auugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7691
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7691
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa cgcaaucaca acuauacuaa cagcaguaac auucugcuuu      240

gccucagguc aaaacauaac agaggaauuu uaccaaucca caugcucugc uguaagcaaa      300

ggauaccucg gagcauuaag aacuggaugg uacaccucag uaauaacuau agaacuauca      360

aacauaaaag aaauaaaaug uaauggcaca gacgcaaaag ugaaauuaau caaacaagaa      420

cucgauaaau acaaaaaugc cguaaccgau cuccaacuuu uaaugcaaag cacacccgca      480

acagguuccg ggucagcaau agcaagcgga guugcaguau gcaaaguacu acacuuagaa      540

ggagaaguaa auaaaaucaa aucagccuua cuaucaacaa auaaagcagu uguaucacuc      600

ucaggaugcg gaguauccgu acuaacauuu aaaguacuag aucuaaaaaa cuacauagau      660

aaacaacucu uaccaauacu aaauaaacaa ucauguucca uacccaacau agaaaccguu      720

aucgaauuuc aacaaaaaaa caacagauua cuagaaauca cacgagaauu uucaguaaau      780

gcuggaguca caacaccagu uaguacauac augcucacca auucagaacu acuaaguuua      840

auuaacgaua ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguacaaaua      900

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguacu agccuaugua      960

guccaauuac cacucuacgg cguaaucgac accccaugcu ggaaauuaca cacaagccca     1020

uuaugcacca ccaacacaaa agaagguuca aacauuugcu uaaccagaac cgaucgagga     1080

ugguacugcg auaacgcagg aucugucucc uuuuucccac aagccgaaac augcaaaguu     1140

caaucaaacc gaguuuucug ugacacuaug aacucacuca cacuuccaag cgaaguaaac     1200

cuaugcaacg uagauauauu uaacccuaaa uacgacugca aaauaaugac aagcaaaaca     1260

gacguuaguu caucaguaau uacaagucua ggcgcaauag ugucaugcua cggaaaaaca     1320

aaaugcaccg cauccaauaa augccgagga aucauuaaaa cauucucaaa cggaugcgac     1380

uacgucagca auaaaggagu agacacuguu ucuguaggaa acacccuaua cuauguaaac     1440

aaacaagaag gucaaucacu auacguaaag ggagaaccaa uuauaaauuu uuacgacccc     1500

uuaguauuuc caagugauga auuugacgca ucuauaaguc aaguuaacga aaaaauuaac     1560

caaucacuug cauuuauaag aaaaucagac gaacuacucc auaauguaaa cgcagguaaa     1620

ucaacaacaa acaucaugau cacaaccaua auaauaguaa uaauuguaau auuacuauca     1680

cuaauagcag uaggauuacu acucuacugc aaagcuagau cuaccccggu cacacucuca     1740

aaagaccaau uaucuggaau aaacaauaua gcauucagca acuaaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7692
<211>  2280
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7692
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagccaa cgccauaacc accauccuca ccgccgucac cuucugcuuc      240

gcuucuggcc aaaacauaac cgaagaguuc uaccaaucca cgugcucugc cgugucaaaa      300

ggcuaccucg gagcccuccg cacagggugg uacacuuccg ucaucaccau cgaacucucu      360

aacaucaaag aaaucaagug caacggcaca gacgcgaaag ucaagcucau caaacaagaa      420

cuagacaaau acaaaaacgc cguaacagac cuccaacucc uaaugcaguc cacaccagcc      480

acaggcuccg gcagcgccau cgccuccggc gucgcugucu gcaaaguccu acaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cuuagcacca acaaagcagu cgucucuuua      600

agcgggugcg gagucucugu ccuaaccuuu aaaguacucg accucaaaaa cuacaucgac      660

aaacaacuac uaccaauacu aaacaaacag agcugcucca uucccaacau cgaaaccguu      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cccgcgaguu cuccgucaac      780

gcaggcguca ccaccccagu cuccaccuau augcuaacca acagcgaacu ccucagccuc      840

aucaaugaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacagaua      900

guccgccagc aguccuacag caucaugugc aucaucaaag aagaagugcu cgccuacgug      960

guacaacucc cucucuacgg agucauugau acacccugcu ggaaacucca cacaagcccc     1020

cucugcacua caaacaccaa agaaggcucu aacauaugcc ucacccgcac agaccguggu     1080

ugguacugcg acaacgccgg cuccguaucc uucuuuccac aagcugaaac cugcaaaguu     1140

caaucaaacc gagucuucug cgacaccaug aacucccuca cauugcccag cgaagucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca aaaucaugac cuccaaaacc     1260

gacgucagcu ccagcgugau cacaagccua ggcgcgaucg ucagcugcua cggcaaaacc     1320

aaaugcacag ccuccaacaa augccgcgga aucauaaaaa cauucaguaa cggcugcgac     1380

uacgugucca auaaaggagu cgacaccgua uccgucggaa acacccucua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca uuaucaacuu cuacgacccc     1500

cuaguuuucc ccuccgacga guucgacgca agcauuuccc aagucaacga aaagaucaau     1560

caaucccucg ccuucauacg caaaagcgac gaacuacuac acaacguaaa cgccggcaaa     1620

agcaccacca acaucaugau cacaacaauc aucaucguca ucaucgucau ccuacucuca     1680

cucaucgccg uuggccuacu acucuacugc aaagcccgcu ccacacccgu cacccucuca     1740

aaagaccaac ucuccggcau caacaacauc gcauucagca acugaggacu agugaaggga     1800

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1860

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1920

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1980

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     2040

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     2100

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2220

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2280


<210>  7693
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7693
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7694
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7694
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7695
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7695
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7696
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7696
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcucaacacc cgugacccug aguaaagauc aacucucugg aaucaauaac auugcuuuca     1680

gcaauugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7697
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7697
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7698
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7698
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaagcacacc cgugacccuu ucuaaagauc aacucuccgg caucaauaac aucgcguuca     1680

gcaauugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7699
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7699
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac      120

uaacagcagu aacauucugc uuugccucag gucaaaacau aacagaggaa uuuuaccaau      180

ccacaugcuc ugcuguaagc aaaggauacc ucggagcauu aagaacugga ugguacaccu      240

caguaauaac uauagaacua ucaaacauaa aagaaauaaa auguaauggc acagacgcaa      300

aagugaaauu aaucaaacaa gaacucgaua aauacaaaaa ugccguaacc gaucuccaac      360

uuuuaaugca aagcacaccc gcaacagguu ccgggucagc aauagcaagc ggaguugcag      420

uaugcaaagu acuacacuua gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa      480

caaauaaagc aguuguauca cucucaggau gcggaguauc cguacuaaca uuuaaaguac      540

uagaucuaaa aaacuacaua gauaaacaac ucuuaccaau acuaaauaaa caaucauguu      600

ccauacccaa cauagaaacc guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa      660

ucacacgaga auuuucagua aaugcuggag ucacaacacc aguuaguaca uacaugcuca      720

ccaauucaga acuacuaagu uuaauuaacg auaugccaau aacaaacgac caaaaaaaac      780

uaaugucaaa uaacguacaa auaguaagac aacaaucaua cucaaucaug ugcauaauaa      840

aagaagaagu acuagccuau guaguccaau uaccacucua cggcguaauc gacaccccau      900

gcuggaaauu acacacaagc ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu      960

gcuuaaccag aaccgaucga ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc     1020

cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacacu augaacucac     1080

ucacacuucc aagcgaagua aaccuaugca acguagauau auuuaacccu aaauacgacu     1140

gcaaaauaau gacaagcaaa acagacguua guucaucagu aauuacaagu cuaggcgcaa     1200

uagugucaug cuacggaaaa acaaaaugca ccgcauccaa uaaaugccga ggaaucauua     1260

aaacauucuc aaacggaugc gacuacguca gcaauaaagg aguagacacu guuucuguag     1320

gaaacacccu auacuaugua aacaaacaag aaggucaauc acuauacgua aagggagaac     1380

caauuauaaa uuuuuacgac cccuuaguau uuccaaguga ugaauuugac gcaucuauaa     1440

gucaaguuaa cgaaaaaauu aaccaaucac uugcauuuau aagaaaauca gacgaacuac     1500

uccauaaugu aaacgcaggu aaaucaacaa caaacaucau gaucacaacc auaauaauag     1560

uaauaauugu aauauuacua ucacuaauag caguaggauu acuacucuac ugcaaagcua     1620

gaucuacccc ggucacacuc ucaaaagacc aauuaucugg aauaaacaau auagcauuca     1680

gcaacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7700
<211>  1963
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7700
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc caacgccaua accaccaucc      120

ucaccgccgu caccuucugc uucgcuucug gccaaaacau aaccgaagag uucuaccaau      180

ccacgugcuc ugccguguca aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu      240

ccgucaucac caucgaacuc ucuaacauca aagaaaucaa gugcaacggc acagacgcga      300

aagucaagcu caucaaacaa gaacuagaca aauacaaaaa cgccguaaca gaccuccaac      360

uccuaaugca guccacacca gccacaggcu ccggcagcgc caucgccucc ggcgucgcug      420

ucugcaaagu ccuacaccuc gaaggcgaag ucaacaaaau caagucagcc cuccuuagca      480

ccaacaaagc agucgucucu uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac      540

ucgaccucaa aaacuacauc gacaaacaac uacuaccaau acuaaacaaa cagagcugcu      600

ccauucccaa caucgaaacc guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucuccguc aacgcaggcg ucaccacccc agucuccacc uauaugcuaa      720

ccaacagcga acuccucagc cucaucaaug acaugccaau caccaacgac caaaagaaac      780

ucauguccaa caacguacag auaguccgcc agcaguccua cagcaucaug ugcaucauca      840

aagaagaagu gcucgccuac gugguacaac ucccucucua cggagucauu gauacacccu      900

gcuggaaacu ccacacaagc ccccucugca cuacaaacac caaagaaggc ucuaacauau      960

gccucacccg cacagaccgu gguugguacu gcgacaacgc cggcuccgua uccuucuuuc     1020

cacaagcuga aaccugcaaa guucaaucaa accgagucuu cugcgacacc augaacuccc     1080

ucacauugcc cagcgaaguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaaaaucau gaccuccaaa accgacguca gcuccagcgu gaucacaagc cuaggcgcga     1200

ucgucagcug cuacggcaaa accaaaugca cagccuccaa caaaugccgc ggaaucauaa     1260

aaacauucag uaacggcugc gacuacgugu ccaauaaagg agucgacacc guauccgucg     1320

gaaacacccu cuacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccauuaucaa cuucuacgac ccccuaguuu uccccuccga cgaguucgac gcaagcauuu     1440

cccaagucaa cgaaaagauc aaucaauccc ucgccuucau acgcaaaagc gacgaacuac     1500

uacacaacgu aaacgccggc aaaagcacca ccaacaucau gaucacaaca aucaucaucg     1560

ucaucaucgu cauccuacuc ucacucaucg ccguuggccu acuacucuac ugcaaagccc     1620

gcuccacacc cgucacccuc ucaaaagacc aacucuccgg caucaacaac aucgcauuca     1680

gcaacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg     1740

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau     1800

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1920

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1963


<210>  7701
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7701
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7702
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7702
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7703
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7703
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7704
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7704
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu caacacccgu gacccugagu     1740

aaagaucaac ucucuggaau caauaacauu gcuuucagca auugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7705
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7705
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7706
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7706
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagaa gcacacccgu gacccuuucu     1740

aaagaucaac ucuccggcau caauaacauc gcguucagca auugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7707
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7707
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa cgcaaucaca acuauacuaa cagcaguaac auucugcuuu      240

gccucagguc aaaacauaac agaggaauuu uaccaaucca caugcucugc uguaagcaaa      300

ggauaccucg gagcauuaag aacuggaugg uacaccucag uaauaacuau agaacuauca      360

aacauaaaag aaauaaaaug uaauggcaca gacgcaaaag ugaaauuaau caaacaagaa      420

cucgauaaau acaaaaaugc cguaaccgau cuccaacuuu uaaugcaaag cacacccgca      480

acagguuccg ggucagcaau agcaagcgga guugcaguau gcaaaguacu acacuuagaa      540

ggagaaguaa auaaaaucaa aucagccuua cuaucaacaa auaaagcagu uguaucacuc      600

ucaggaugcg gaguauccgu acuaacauuu aaaguacuag aucuaaaaaa cuacauagau      660

aaacaacucu uaccaauacu aaauaaacaa ucauguucca uacccaacau agaaaccguu      720

aucgaauuuc aacaaaaaaa caacagauua cuagaaauca cacgagaauu uucaguaaau      780

gcuggaguca caacaccagu uaguacauac augcucacca auucagaacu acuaaguuua      840

auuaacgaua ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguacaaaua      900

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguacu agccuaugua      960

guccaauuac cacucuacgg cguaaucgac accccaugcu ggaaauuaca cacaagccca     1020

uuaugcacca ccaacacaaa agaagguuca aacauuugcu uaaccagaac cgaucgagga     1080

ugguacugcg auaacgcagg aucugucucc uuuuucccac aagccgaaac augcaaaguu     1140

caaucaaacc gaguuuucug ugacacuaug aacucacuca cacuuccaag cgaaguaaac     1200

cuaugcaacg uagauauauu uaacccuaaa uacgacugca aaauaaugac aagcaaaaca     1260

gacguuaguu caucaguaau uacaagucua ggcgcaauag ugucaugcua cggaaaaaca     1320

aaaugcaccg cauccaauaa augccgagga aucauuaaaa cauucucaaa cggaugcgac     1380

uacgucagca auaaaggagu agacacuguu ucuguaggaa acacccuaua cuauguaaac     1440

aaacaagaag gucaaucacu auacguaaag ggagaaccaa uuauaaauuu uuacgacccc     1500

uuaguauuuc caagugauga auuugacgca ucuauaaguc aaguuaacga aaaaauuaac     1560

caaucacuug cauuuauaag aaaaucagac gaacuacucc auaauguaaa cgcagguaaa     1620

ucaacaacaa acaucaugau cacaaccaua auaauaguaa uaauuguaau auuacuauca     1680

cuaauagcag uaggauuacu acucuacugc aaagcuagau cuaccccggu cacacucuca     1740

aaagaccaau uaucuggaau aaacaauaua gcauucagca acuaaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7708
<211>  2060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7708
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagccaa cgccauaacc accauccuca ccgccgucac cuucugcuuc      240

gcuucuggcc aaaacauaac cgaagaguuc uaccaaucca cgugcucugc cgugucaaaa      300

ggcuaccucg gagcccuccg cacagggugg uacacuuccg ucaucaccau cgaacucucu      360

aacaucaaag aaaucaagug caacggcaca gacgcgaaag ucaagcucau caaacaagaa      420

cuagacaaau acaaaaacgc cguaacagac cuccaacucc uaaugcaguc cacaccagcc      480

acaggcuccg gcagcgccau cgccuccggc gucgcugucu gcaaaguccu acaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cuuagcacca acaaagcagu cgucucuuua      600

agcgggugcg gagucucugu ccuaaccuuu aaaguacucg accucaaaaa cuacaucgac      660

aaacaacuac uaccaauacu aaacaaacag agcugcucca uucccaacau cgaaaccguu      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cccgcgaguu cuccgucaac      780

gcaggcguca ccaccccagu cuccaccuau augcuaacca acagcgaacu ccucagccuc      840

aucaaugaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacagaua      900

guccgccagc aguccuacag caucaugugc aucaucaaag aagaagugcu cgccuacgug      960

guacaacucc cucucuacgg agucauugau acacccugcu ggaaacucca cacaagcccc     1020

cucugcacua caaacaccaa agaaggcucu aacauaugcc ucacccgcac agaccguggu     1080

ugguacugcg acaacgccgg cuccguaucc uucuuuccac aagcugaaac cugcaaaguu     1140

caaucaaacc gagucuucug cgacaccaug aacucccuca cauugcccag cgaagucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca aaaucaugac cuccaaaacc     1260

gacgucagcu ccagcgugau cacaagccua ggcgcgaucg ucagcugcua cggcaaaacc     1320

aaaugcacag ccuccaacaa augccgcgga aucauaaaaa cauucaguaa cggcugcgac     1380

uacgugucca auaaaggagu cgacaccgua uccgucggaa acacccucua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca uuaucaacuu cuacgacccc     1500

cuaguuuucc ccuccgacga guucgacgca agcauuuccc aagucaacga aaagaucaau     1560

caaucccucg ccuucauacg caaaagcgac gaacuacuac acaacguaaa cgccggcaaa     1620

agcaccacca acaucaugau cacaacaauc aucaucguca ucaucgucau ccuacucuca     1680

cucaucgccg uuggccuacu acucuacugc aaagcccgcu ccacacccgu cacccucuca     1740

aaagaccaac ucuccggcau caacaacauc gcauucagca acugaggacu aguggaagca     1800

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1860

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1920

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2040

uuuucagagc caccagaauu                                                 2060


<210>  7709
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7709
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      660

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      720

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      780

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      900

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      960

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1020

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1080

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1260

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1380

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1440

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1560

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1620

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1680

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7710
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7710
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      540

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      600

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      660

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      720

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc      960

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg     1020

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1140

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1200

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1260

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1380

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1440

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1500

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1560

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1620

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguccacccc cgugacccug     1680

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7711
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7711
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      600

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      660

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      720

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      840

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      900

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      960

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1020

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1260

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1320

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1380

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1440

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1500

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1560

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1620

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1680

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7712
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7712
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      360

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      480

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      540

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      600

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      660

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      720

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      780

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      840

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau      900

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      960

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu     1020

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1080

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1140

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1200

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1260

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1320

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1380

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1440

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1500

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1560

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1620

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcucaacacc cgugacccug     1680

aguaaagauc aacucucugg aaucaauaac auugcuuuca gcaauugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7713
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7713
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      660

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      720

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      780

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      960

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1020

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1080

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1140

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1200

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1260

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1380

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1440

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1560

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1620

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1680

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7714
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7714
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      360

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      480

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      540

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      600

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      660

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      720

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      780

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      840

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau      900

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc      960

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc     1020

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1080

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1140

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1200

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1260

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1320

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1380

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1440

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1500

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1560

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1620

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaagcacacc cgugacccuu     1680

ucuaaagauc aacucuccgg caucaauaac aucgcguuca gcaauugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7715
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7715
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac uaacagcagu aacauucugc      180

uuugccucag gucaaaacau aacagaggaa uuuuaccaau ccacaugcuc ugcuguaagc      240

aaaggauacc ucggagcauu aagaacugga ugguacaccu caguaauaac uauagaacua      300

ucaaacauaa aagaaauaaa auguaauggc acagacgcaa aagugaaauu aaucaaacaa      360

gaacucgaua aauacaaaaa ugccguaacc gaucuccaac uuuuaaugca aagcacaccc      420

gcaacagguu ccgggucagc aauagcaagc ggaguugcag uaugcaaagu acuacacuua      480

gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa caaauaaagc aguuguauca      540

cucucaggau gcggaguauc cguacuaaca uuuaaaguac uagaucuaaa aaacuacaua      600

gauaaacaac ucuuaccaau acuaaauaaa caaucauguu ccauacccaa cauagaaacc      660

guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa ucacacgaga auuuucagua      720

aaugcuggag ucacaacacc aguuaguaca uacaugcuca ccaauucaga acuacuaagu      780

uuaauuaacg auaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      840

auaguaagac aacaaucaua cucaaucaug ugcauaauaa aagaagaagu acuagccuau      900

guaguccaau uaccacucua cggcguaauc gacaccccau gcuggaaauu acacacaagc      960

ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu gcuuaaccag aaccgaucga     1020

ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc cacaagccga aacaugcaaa     1080

guucaaucaa accgaguuuu cugugacacu augaacucac ucacacuucc aagcgaagua     1140

aaccuaugca acguagauau auuuaacccu aaauacgacu gcaaaauaau gacaagcaaa     1200

acagacguua guucaucagu aauuacaagu cuaggcgcaa uagugucaug cuacggaaaa     1260

acaaaaugca ccgcauccaa uaaaugccga ggaaucauua aaacauucuc aaacggaugc     1320

gacuacguca gcaauaaagg aguagacacu guuucuguag gaaacacccu auacuaugua     1380

aacaaacaag aaggucaauc acuauacgua aagggagaac caauuauaaa uuuuuacgac     1440

cccuuaguau uuccaaguga ugaauuugac gcaucuauaa gucaaguuaa cgaaaaaauu     1500

aaccaaucac uugcauuuau aagaaaauca gacgaacuac uccauaaugu aaacgcaggu     1560

aaaucaacaa caaacaucau gaucacaacc auaauaauag uaauaauugu aauauuacua     1620

ucacuaauag caguaggauu acuacucuac ugcaaagcua gaucuacccc ggucacacuc     1680

ucaaaagacc aauuaucugg aauaaacaau auagcauuca gcaacuaagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7716
<211>  1940
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7716
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccuuaaagc caacgccaua accaccaucc ucaccgccgu caccuucugc      180

uucgcuucug gccaaaacau aaccgaagag uucuaccaau ccacgugcuc ugccguguca      240

aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu ccgucaucac caucgaacuc      300

ucuaacauca aagaaaucaa gugcaacggc acagacgcga aagucaagcu caucaaacaa      360

gaacuagaca aauacaaaaa cgccguaaca gaccuccaac uccuaaugca guccacacca      420

gccacaggcu ccggcagcgc caucgccucc ggcgucgcug ucugcaaagu ccuacaccuc      480

gaaggcgaag ucaacaaaau caagucagcc cuccuuagca ccaacaaagc agucgucucu      540

uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac ucgaccucaa aaacuacauc      600

gacaaacaac uacuaccaau acuaaacaaa cagagcugcu ccauucccaa caucgaaacc      660

guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa ucacccgcga guucuccguc      720

aacgcaggcg ucaccacccc agucuccacc uauaugcuaa ccaacagcga acuccucagc      780

cucaucaaug acaugccaau caccaacgac caaaagaaac ucauguccaa caacguacag      840

auaguccgcc agcaguccua cagcaucaug ugcaucauca aagaagaagu gcucgccuac      900

gugguacaac ucccucucua cggagucauu gauacacccu gcuggaaacu ccacacaagc      960

ccccucugca cuacaaacac caaagaaggc ucuaacauau gccucacccg cacagaccgu     1020

gguugguacu gcgacaacgc cggcuccgua uccuucuuuc cacaagcuga aaccugcaaa     1080

guucaaucaa accgagucuu cugcgacacc augaacuccc ucacauugcc cagcgaaguc     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaaaaucau gaccuccaaa     1200

accgacguca gcuccagcgu gaucacaagc cuaggcgcga ucgucagcug cuacggcaaa     1260

accaaaugca cagccuccaa caaaugccgc ggaaucauaa aaacauucag uaacggcugc     1320

gacuacgugu ccaauaaagg agucgacacc guauccgucg gaaacacccu cuacuacguc     1380

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccauuaucaa cuucuacgac     1440

ccccuaguuu uccccuccga cgaguucgac gcaagcauuu cccaagucaa cgaaaagauc     1500

aaucaauccc ucgccuucau acgcaaaagc gacgaacuac uacacaacgu aaacgccggc     1560

aaaagcacca ccaacaucau gaucacaaca aucaucaucg ucaucaucgu cauccuacuc     1620

ucacucaucg ccguuggccu acuacucuac ugcaaagccc gcuccacacc cgucacccuc     1680

ucaaaagacc aacucuccgg caucaacaac aucgcauuca gcaacugagg acuagugucc     1740

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1800

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1920

uuuucagagc caccagaauu                                                 1940


<210>  7717
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7717
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7718
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7718
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccgguccacc cccgugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7719
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7719
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7720
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7720
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcucaaca cccgugaccc ugaguaaaga ucaacucucu     1680

ggaaucaaua acauugcuuu cagcaauuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7721
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7721
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7722
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7722
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaagcaca cccgugaccc uuucuaaaga ucaacucucc     1680

ggcaucaaua acaucgcguu cagcaauuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7723
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7723
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaacgcaa ucacaacuau acuaacagca guaacauucu gcuuugccuc aggucaaaac      180

auaacagagg aauuuuacca auccacaugc ucugcuguaa gcaaaggaua ccucggagca      240

uuaagaacug gaugguacac cucaguaaua acuauagaac uaucaaacau aaaagaaaua      300

aaauguaaug gcacagacgc aaaagugaaa uuaaucaaac aagaacucga uaaauacaaa      360

aaugccguaa ccgaucucca acuuuuaaug caaagcacac ccgcaacagg uuccggguca      420

gcaauagcaa gcggaguugc aguaugcaaa guacuacacu uagaaggaga aguaaauaaa      480

aucaaaucag ccuuacuauc aacaaauaaa gcaguuguau cacucucagg augcggagua      540

uccguacuaa cauuuaaagu acuagaucua aaaaacuaca uagauaaaca acucuuacca      600

auacuaaaua aacaaucaug uuccauaccc aacauagaaa ccguuaucga auuucaacaa      660

aaaaacaaca gauuacuaga aaucacacga gaauuuucag uaaaugcugg agucacaaca      720

ccaguuagua cauacaugcu caccaauuca gaacuacuaa guuuaauuaa cgauaugcca      780

auaacaaacg accaaaaaaa acuaauguca aauaacguac aaauaguaag acaacaauca      840

uacucaauca ugugcauaau aaaagaagaa guacuagccu auguagucca auuaccacuc      900

uacggcguaa ucgacacccc augcuggaaa uuacacacaa gcccauuaug caccaccaac      960

acaaaagaag guucaaacau uugcuuaacc agaaccgauc gaggauggua cugcgauaac     1020

gcaggaucug ucuccuuuuu cccacaagcc gaaacaugca aaguucaauc aaaccgaguu     1080

uucugugaca cuaugaacuc acucacacuu ccaagcgaag uaaaccuaug caacguagau     1140

auauuuaacc cuaaauacga cugcaaaaua augacaagca aaacagacgu uaguucauca     1200

guaauuacaa gucuaggcgc aauaguguca ugcuacggaa aaacaaaaug caccgcaucc     1260

aauaaaugcc gaggaaucau uaaaacauuc ucaaacggau gcgacuacgu cagcaauaaa     1320

ggaguagaca cuguuucugu aggaaacacc cuauacuaug uaaacaaaca agaaggucaa     1380

ucacuauacg uaaagggaga accaauuaua aauuuuuacg accccuuagu auuuccaagu     1440

gaugaauuug acgcaucuau aagucaaguu aacgaaaaaa uuaaccaauc acuugcauuu     1500

auaagaaaau cagacgaacu acuccauaau guaaacgcag guaaaucaac aacaaacauc     1560

augaucacaa ccauaauaau aguaauaauu guaauauuac uaucacuaau agcaguagga     1620

uuacuacucu acugcaaagc uagaucuacc ccggucacac ucucaaaaga ccaauuaucu     1680

ggaauaaaca auauagcauu cagcaacuaa ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7724
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7724
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gccaacgcca uaaccaccau ccucaccgcc gucaccuucu gcuucgcuuc uggccaaaac      180

auaaccgaag aguucuacca auccacgugc ucugccgugu caaaaggcua ccucggagcc      240

cuccgcacag ggugguacac uuccgucauc accaucgaac ucucuaacau caaagaaauc      300

aagugcaacg gcacagacgc gaaagucaag cucaucaaac aagaacuaga caaauacaaa      360

aacgccguaa cagaccucca acuccuaaug caguccacac cagccacagg cuccggcagc      420

gccaucgccu ccggcgucgc ugucugcaaa guccuacacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccuuag caccaacaaa gcagucgucu cuuuaagcgg gugcggaguc      540

ucuguccuaa ccuuuaaagu acucgaccuc aaaaacuaca ucgacaaaca acuacuacca      600

auacuaaaca aacagagcug cuccauuccc aacaucgaaa ccguuaucga guuccaacaa      660

aagaacaacc gccuccucga aaucacccgc gaguucuccg ucaacgcagg cgucaccacc      720

ccagucucca ccuauaugcu aaccaacagc gaacuccuca gccucaucaa ugacaugcca      780

aucaccaacg accaaaagaa acucaugucc aacaacguac agauaguccg ccagcagucc      840

uacagcauca ugugcaucau caaagaagaa gugcucgccu acgugguaca acucccucuc      900

uacggaguca uugauacacc cugcuggaaa cuccacacaa gcccccucug cacuacaaac      960

accaaagaag gcucuaacau augccucacc cgcacagacc gugguuggua cugcgacaac     1020

gccggcuccg uauccuucuu uccacaagcu gaaaccugca aaguucaauc aaaccgaguc     1080

uucugcgaca ccaugaacuc ccucacauug cccagcgaag ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaaaauc augaccucca aaaccgacgu cagcuccagc     1200

gugaucacaa gccuaggcgc gaucgucagc ugcuacggca aaaccaaaug cacagccucc     1260

aacaaaugcc gcggaaucau aaaaacauuc aguaacggcu gcgacuacgu guccaauaaa     1320

ggagucgaca ccguauccgu cggaaacacc cucuacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccauuauc aacuucuacg acccccuagu uuuccccucc     1440

gacgaguucg acgcaagcau uucccaaguc aacgaaaaga ucaaucaauc ccucgccuuc     1500

auacgcaaaa gcgacgaacu acuacacaac guaaacgccg gcaaaagcac caccaacauc     1560

augaucacaa caaucaucau cgucaucauc gucauccuac ucucacucau cgccguuggc     1620

cuacuacucu acugcaaagc ccgcuccaca cccgucaccc ucucaaaaga ccaacucucc     1680

ggcaucaaca acaucgcauu cagcaacuga ggacuagugu ccaccugucc cuccugggcu     1740

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  7725
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7725
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7726
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7726
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccgguccacc     1620

cccgugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7727
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7727
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7728
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7728
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcucaaca     1620

cccgugaccc ugaguaaaga ucaacucucu ggaaucaaua acauugcuuu cagcaauuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7729
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7729
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7730
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7730
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaagcaca     1620

cccgugaccc uuucuaaaga ucaacucucc ggcaucaaua acaucgcguu cagcaauuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7731
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7731
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaacgcaa ucacaacuau acuaacagca      120

guaacauucu gcuuugccuc aggucaaaac auaacagagg aauuuuacca auccacaugc      180

ucugcuguaa gcaaaggaua ccucggagca uuaagaacug gaugguacac cucaguaaua      240

acuauagaac uaucaaacau aaaagaaaua aaauguaaug gcacagacgc aaaagugaaa      300

uuaaucaaac aagaacucga uaaauacaaa aaugccguaa ccgaucucca acuuuuaaug      360

caaagcacac ccgcaacagg uuccggguca gcaauagcaa gcggaguugc aguaugcaaa      420

guacuacacu uagaaggaga aguaaauaaa aucaaaucag ccuuacuauc aacaaauaaa      480

gcaguuguau cacucucagg augcggagua uccguacuaa cauuuaaagu acuagaucua      540

aaaaacuaca uagauaaaca acucuuacca auacuaaaua aacaaucaug uuccauaccc      600

aacauagaaa ccguuaucga auuucaacaa aaaaacaaca gauuacuaga aaucacacga      660

gaauuuucag uaaaugcugg agucacaaca ccaguuagua cauacaugcu caccaauuca      720

gaacuacuaa guuuaauuaa cgauaugcca auaacaaacg accaaaaaaa acuaauguca      780

aauaacguac aaauaguaag acaacaauca uacucaauca ugugcauaau aaaagaagaa      840

guacuagccu auguagucca auuaccacuc uacggcguaa ucgacacccc augcuggaaa      900

uuacacacaa gcccauuaug caccaccaac acaaaagaag guucaaacau uugcuuaacc      960

agaaccgauc gaggauggua cugcgauaac gcaggaucug ucuccuuuuu cccacaagcc     1020

gaaacaugca aaguucaauc aaaccgaguu uucugugaca cuaugaacuc acucacacuu     1080

ccaagcgaag uaaaccuaug caacguagau auauuuaacc cuaaauacga cugcaaaaua     1140

augacaagca aaacagacgu uaguucauca guaauuacaa gucuaggcgc aauaguguca     1200

ugcuacggaa aaacaaaaug caccgcaucc aauaaaugcc gaggaaucau uaaaacauuc     1260

ucaaacggau gcgacuacgu cagcaauaaa ggaguagaca cuguuucugu aggaaacacc     1320

cuauacuaug uaaacaaaca agaaggucaa ucacuauacg uaaagggaga accaauuaua     1380

aauuuuuacg accccuuagu auuuccaagu gaugaauuug acgcaucuau aagucaaguu     1440

aacgaaaaaa uuaaccaauc acuugcauuu auaagaaaau cagacgaacu acuccauaau     1500

guaaacgcag guaaaucaac aacaaacauc augaucacaa ccauaauaau aguaauaauu     1560

guaauauuac uaucacuaau agcaguagga uuacuacucu acugcaaagc uagaucuacc     1620

ccggucacac ucucaaaaga ccaauuaucu ggaauaaaca auauagcauu cagcaacuaa     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7732
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7732
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gccaacgcca uaaccaccau ccucaccgcc      120

gucaccuucu gcuucgcuuc uggccaaaac auaaccgaag aguucuacca auccacgugc      180

ucugccgugu caaaaggcua ccucggagcc cuccgcacag ggugguacac uuccgucauc      240

accaucgaac ucucuaacau caaagaaauc aagugcaacg gcacagacgc gaaagucaag      300

cucaucaaac aagaacuaga caaauacaaa aacgccguaa cagaccucca acuccuaaug      360

caguccacac cagccacagg cuccggcagc gccaucgccu ccggcgucgc ugucugcaaa      420

guccuacacc ucgaaggcga agucaacaaa aucaagucag cccuccuuag caccaacaaa      480

gcagucgucu cuuuaagcgg gugcggaguc ucuguccuaa ccuuuaaagu acucgaccuc      540

aaaaacuaca ucgacaaaca acuacuacca auacuaaaca aacagagcug cuccauuccc      600

aacaucgaaa ccguuaucga guuccaacaa aagaacaacc gccuccucga aaucacccgc      660

gaguucuccg ucaacgcagg cgucaccacc ccagucucca ccuauaugcu aaccaacagc      720

gaacuccuca gccucaucaa ugacaugcca aucaccaacg accaaaagaa acucaugucc      780

aacaacguac agauaguccg ccagcagucc uacagcauca ugugcaucau caaagaagaa      840

gugcucgccu acgugguaca acucccucuc uacggaguca uugauacacc cugcuggaaa      900

cuccacacaa gcccccucug cacuacaaac accaaagaag gcucuaacau augccucacc      960

cgcacagacc gugguuggua cugcgacaac gccggcuccg uauccuucuu uccacaagcu     1020

gaaaccugca aaguucaauc aaaccgaguc uucugcgaca ccaugaacuc ccucacauug     1080

cccagcgaag ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaaaauc     1140

augaccucca aaaccgacgu cagcuccagc gugaucacaa gccuaggcgc gaucgucagc     1200

ugcuacggca aaaccaaaug cacagccucc aacaaaugcc gcggaaucau aaaaacauuc     1260

aguaacggcu gcgacuacgu guccaauaaa ggagucgaca ccguauccgu cggaaacacc     1320

cucuacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccauuauc     1380

aacuucuacg acccccuagu uuuccccucc gacgaguucg acgcaagcau uucccaaguc     1440

aacgaaaaga ucaaucaauc ccucgccuuc auacgcaaaa gcgacgaacu acuacacaac     1500

guaaacgccg gcaaaagcac caccaacauc augaucacaa caaucaucau cgucaucauc     1560

gucauccuac ucucacucau cgccguuggc cuacuacucu acugcaaagc ccgcuccaca     1620

cccgucaccc ucucaaaaga ccaacucucc ggcaucaaca acaucgcauu cagcaacuga     1680

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa     1740

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  7733
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7733
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7734
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7734
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccgguc cacccccgug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7735
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7735
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7736
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7736
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcuc aacacccgug     1680

acccugagua aagaucaacu cucuggaauc aauaacauug cuuucagcaa uugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7737
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7737
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7738
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7738
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaag cacacccgug     1680

acccuuucua aagaucaacu cuccggcauc aauaacaucg cguucagcaa uugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7739
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7739
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaac gcaaucacaa cuauacuaac agcaguaaca      180

uucugcuuug ccucagguca aaacauaaca gaggaauuuu accaauccac augcucugcu      240

guaagcaaag gauaccucgg agcauuaaga acuggauggu acaccucagu aauaacuaua      300

gaacuaucaa acauaaaaga aauaaaaugu aauggcacag acgcaaaagu gaaauuaauc      360

aaacaagaac ucgauaaaua caaaaaugcc guaaccgauc uccaacuuuu aaugcaaagc      420

acacccgcaa cagguuccgg gucagcaaua gcaagcggag uugcaguaug caaaguacua      480

cacuuagaag gagaaguaaa uaaaaucaaa ucagccuuac uaucaacaaa uaaagcaguu      540

guaucacucu caggaugcgg aguauccgua cuaacauuua aaguacuaga ucuaaaaaac      600

uacauagaua aacaacucuu accaauacua aauaaacaau cauguuccau acccaacaua      660

gaaaccguua ucgaauuuca acaaaaaaac aacagauuac uagaaaucac acgagaauuu      720

ucaguaaaug cuggagucac aacaccaguu aguacauaca ugcucaccaa uucagaacua      780

cuaaguuuaa uuaacgauau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      840

guacaaauag uaagacaaca aucauacuca aucaugugca uaauaaaaga agaaguacua      900

gccuauguag uccaauuacc acucuacggc guaaucgaca ccccaugcug gaaauuacac      960

acaagcccau uaugcaccac caacacaaaa gaagguucaa acauuugcuu aaccagaacc     1020

gaucgaggau gguacugcga uaacgcagga ucugucuccu uuuucccaca agccgaaaca     1080

ugcaaaguuc aaucaaaccg aguuuucugu gacacuauga acucacucac acuuccaagc     1140

gaaguaaacc uaugcaacgu agauauauuu aacccuaaau acgacugcaa aauaaugaca     1200

agcaaaacag acguuaguuc aucaguaauu acaagucuag gcgcaauagu gucaugcuac     1260

ggaaaaacaa aaugcaccgc auccaauaaa ugccgaggaa ucauuaaaac auucucaaac     1320

ggaugcgacu acgucagcaa uaaaggagua gacacuguuu cuguaggaaa cacccuauac     1380

uauguaaaca aacaagaagg ucaaucacua uacguaaagg gagaaccaau uauaaauuuu     1440

uacgaccccu uaguauuucc aagugaugaa uuugacgcau cuauaaguca aguuaacgaa     1500

aaaauuaacc aaucacuugc auuuauaaga aaaucagacg aacuacucca uaauguaaac     1560

gcagguaaau caacaacaaa caucaugauc acaaccauaa uaauaguaau aauuguaaua     1620

uuacuaucac uaauagcagu aggauuacua cucuacugca aagcuagauc uaccccgguc     1680

acacucucaa aagaccaauu aucuggaaua aacaauauag cauucagcaa cuaaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7740
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7740
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagccaac gccauaacca ccauccucac cgccgucacc      180

uucugcuucg cuucuggcca aaacauaacc gaagaguucu accaauccac gugcucugcc      240

gugucaaaag gcuaccucgg agcccuccgc acaggguggu acacuuccgu caucaccauc      300

gaacucucua acaucaaaga aaucaagugc aacggcacag acgcgaaagu caagcucauc      360

aaacaagaac uagacaaaua caaaaacgcc guaacagacc uccaacuccu aaugcagucc      420

acaccagcca caggcuccgg cagcgccauc gccuccggcg ucgcugucug caaaguccua      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc uuagcaccaa caaagcaguc      540

gucucuuuaa gcgggugcgg agucucuguc cuaaccuuua aaguacucga ccucaaaaac      600

uacaucgaca aacaacuacu accaauacua aacaaacaga gcugcuccau ucccaacauc      660

gaaaccguua ucgaguucca acaaaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

uccgucaacg caggcgucac caccccaguc uccaccuaua ugcuaaccaa cagcgaacuc      780

cucagccuca ucaaugacau gccaaucacc aacgaccaaa agaaacucau guccaacaac      840

guacagauag uccgccagca guccuacagc aucaugugca ucaucaaaga agaagugcuc      900

gccuacgugg uacaacuccc ucucuacgga gucauugaua cacccugcug gaaacuccac      960

acaagccccc ucugcacuac aaacaccaaa gaaggcucua acauaugccu cacccgcaca     1020

gaccgugguu gguacugcga caacgccggc uccguauccu ucuuuccaca agcugaaacc     1080

ugcaaaguuc aaucaaaccg agucuucugc gacaccauga acucccucac auugcccagc     1140

gaagucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa aaucaugacc     1200

uccaaaaccg acgucagcuc cagcgugauc acaagccuag gcgcgaucgu cagcugcuac     1260

ggcaaaacca aaugcacagc cuccaacaaa ugccgcggaa ucauaaaaac auucaguaac     1320

ggcugcgacu acguguccaa uaaaggaguc gacaccguau ccgucggaaa cacccucuac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau uaucaacuuc     1440

uacgaccccc uaguuuuccc cuccgacgag uucgacgcaa gcauuuccca agucaacgaa     1500

aagaucaauc aaucccucgc cuucauacgc aaaagcgacg aacuacuaca caacguaaac     1560

gccggcaaaa gcaccaccaa caucaugauc acaacaauca ucaucgucau caucgucauc     1620

cuacucucac ucaucgccgu uggccuacua cucuacugca aagcccgcuc cacacccguc     1680

acccucucaa aagaccaacu cuccggcauc aacaacaucg cauucagcaa cugaggacua     1740

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga     1800

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  7741
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7741
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7742
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7742
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccgguccac ccccgugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7743
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7743
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7744
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7744
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcucaac acccgugacc cugaguaaag aucaacucuc uggaaucaau     1680

aacauugcuu ucagcaauug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7745
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7745
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7746
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7746
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaagcac acccgugacc cuuucuaaag aucaacucuc cggcaucaau     1680

aacaucgcgu ucagcaauug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7747
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7747
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaacgca      120

aucacaacua uacuaacagc aguaacauuc ugcuuugccu caggucaaaa cauaacagag      180

gaauuuuacc aauccacaug cucugcugua agcaaaggau accucggagc auuaagaacu      240

ggaugguaca ccucaguaau aacuauagaa cuaucaaaca uaaaagaaau aaaauguaau      300

ggcacagacg caaaagugaa auuaaucaaa caagaacucg auaaauacaa aaaugccgua      360

accgaucucc aacuuuuaau gcaaagcaca cccgcaacag guuccggguc agcaauagca      420

agcggaguug caguaugcaa aguacuacac uuagaaggag aaguaaauaa aaucaaauca      480

gccuuacuau caacaaauaa agcaguugua ucacucucag gaugcggagu auccguacua      540

acauuuaaag uacuagaucu aaaaaacuac auagauaaac aacucuuacc aauacuaaau      600

aaacaaucau guuccauacc caacauagaa accguuaucg aauuucaaca aaaaaacaac      660

agauuacuag aaaucacacg agaauuuuca guaaaugcug gagucacaac accaguuagu      720

acauacaugc ucaccaauuc agaacuacua aguuuaauua acgauaugcc aauaacaaac      780

gaccaaaaaa aacuaauguc aaauaacgua caaauaguaa gacaacaauc auacucaauc      840

augugcauaa uaaaagaaga aguacuagcc uauguagucc aauuaccacu cuacggcgua      900

aucgacaccc caugcuggaa auuacacaca agcccauuau gcaccaccaa cacaaaagaa      960

gguucaaaca uuugcuuaac cagaaccgau cgaggauggu acugcgauaa cgcaggaucu     1020

gucuccuuuu ucccacaagc cgaaacaugc aaaguucaau caaaccgagu uuucugugac     1080

acuaugaacu cacucacacu uccaagcgaa guaaaccuau gcaacguaga uauauuuaac     1140

ccuaaauacg acugcaaaau aaugacaagc aaaacagacg uuaguucauc aguaauuaca     1200

agucuaggcg caauaguguc augcuacgga aaaacaaaau gcaccgcauc caauaaaugc     1260

cgaggaauca uuaaaacauu cucaaacgga ugcgacuacg ucagcaauaa aggaguagac     1320

acuguuucug uaggaaacac ccuauacuau guaaacaaac aagaagguca aucacuauac     1380

guaaagggag aaccaauuau aaauuuuuac gaccccuuag uauuuccaag ugaugaauuu     1440

gacgcaucua uaagucaagu uaacgaaaaa auuaaccaau cacuugcauu uauaagaaaa     1500

ucagacgaac uacuccauaa uguaaacgca gguaaaucaa caacaaacau caugaucaca     1560

accauaauaa uaguaauaau uguaauauua cuaucacuaa uagcaguagg auuacuacuc     1620

uacugcaaag cuagaucuac cccggucaca cucucaaaag accaauuauc uggaauaaac     1680

aauauagcau ucagcaacua aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7748
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7748
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agccaacgcc      120

auaaccacca uccucaccgc cgucaccuuc ugcuucgcuu cuggccaaaa cauaaccgaa      180

gaguucuacc aauccacgug cucugccgug ucaaaaggcu accucggagc ccuccgcaca      240

gggugguaca cuuccgucau caccaucgaa cucucuaaca ucaaagaaau caagugcaac      300

ggcacagacg cgaaagucaa gcucaucaaa caagaacuag acaaauacaa aaacgccgua      360

acagaccucc aacuccuaau gcaguccaca ccagccacag gcuccggcag cgccaucgcc      420

uccggcgucg cugucugcaa aguccuacac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccuua gcaccaacaa agcagucguc ucuuuaagcg ggugcggagu cucuguccua      540

accuuuaaag uacucgaccu caaaaacuac aucgacaaac aacuacuacc aauacuaaac      600

aaacagagcu gcuccauucc caacaucgaa accguuaucg aguuccaaca aaagaacaac      660

cgccuccucg aaaucacccg cgaguucucc gucaacgcag gcgucaccac cccagucucc      720

accuauaugc uaaccaacag cgaacuccuc agccucauca augacaugcc aaucaccaac      780

gaccaaaaga aacucauguc caacaacgua cagauagucc gccagcaguc cuacagcauc      840

augugcauca ucaaagaaga agugcucgcc uacgugguac aacucccucu cuacggaguc      900

auugauacac ccugcuggaa acuccacaca agcccccucu gcacuacaaa caccaaagaa      960

ggcucuaaca uaugccucac ccgcacagac cgugguuggu acugcgacaa cgccggcucc     1020

guauccuucu uuccacaagc ugaaaccugc aaaguucaau caaaccgagu cuucugcgac     1080

accaugaacu cccucacauu gcccagcgaa gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaaaau caugaccucc aaaaccgacg ucagcuccag cgugaucaca     1200

agccuaggcg cgaucgucag cugcuacggc aaaaccaaau gcacagccuc caacaaaugc     1260

cgcggaauca uaaaaacauu caguaacggc ugcgacuacg uguccaauaa aggagucgac     1320

accguauccg ucggaaacac ccucuacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccauuau caacuucuac gacccccuag uuuuccccuc cgacgaguuc     1440

gacgcaagca uuucccaagu caacgaaaag aucaaucaau cccucgccuu cauacgcaaa     1500

agcgacgaac uacuacacaa cguaaacgcc ggcaaaagca ccaccaacau caugaucaca     1560

acaaucauca ucgucaucau cgucauccua cucucacuca ucgccguugg ccuacuacuc     1620

uacugcaaag cccgcuccac acccgucacc cucucaaaag accaacucuc cggcaucaac     1680

aacaucgcau ucagcaacug aggacuagug uccaccuguc ccuccugggc ugcuggauug     1740

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  7749
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7749
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7750
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7750
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccgguccac ccccgugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7751
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7751
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7752
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7752
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcucaac acccgugacc cugaguaaag aucaacucuc uggaaucaau     1680

aacauugcuu ucagcaauug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7753
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7753
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7754
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7754
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaagcac acccgugacc cuuucuaaag aucaacucuc cggcaucaau     1680

aacaucgcgu ucagcaauug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7755
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7755
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaacgca      120

aucacaacua uacuaacagc aguaacauuc ugcuuugccu caggucaaaa cauaacagag      180

gaauuuuacc aauccacaug cucugcugua agcaaaggau accucggagc auuaagaacu      240

ggaugguaca ccucaguaau aacuauagaa cuaucaaaca uaaaagaaau aaaauguaau      300

ggcacagacg caaaagugaa auuaaucaaa caagaacucg auaaauacaa aaaugccgua      360

accgaucucc aacuuuuaau gcaaagcaca cccgcaacag guuccggguc agcaauagca      420

agcggaguug caguaugcaa aguacuacac uuagaaggag aaguaaauaa aaucaaauca      480

gccuuacuau caacaaauaa agcaguugua ucacucucag gaugcggagu auccguacua      540

acauuuaaag uacuagaucu aaaaaacuac auagauaaac aacucuuacc aauacuaaau      600

aaacaaucau guuccauacc caacauagaa accguuaucg aauuucaaca aaaaaacaac      660

agauuacuag aaaucacacg agaauuuuca guaaaugcug gagucacaac accaguuagu      720

acauacaugc ucaccaauuc agaacuacua aguuuaauua acgauaugcc aauaacaaac      780

gaccaaaaaa aacuaauguc aaauaacgua caaauaguaa gacaacaauc auacucaauc      840

augugcauaa uaaaagaaga aguacuagcc uauguagucc aauuaccacu cuacggcgua      900

aucgacaccc caugcuggaa auuacacaca agcccauuau gcaccaccaa cacaaaagaa      960

gguucaaaca uuugcuuaac cagaaccgau cgaggauggu acugcgauaa cgcaggaucu     1020

gucuccuuuu ucccacaagc cgaaacaugc aaaguucaau caaaccgagu uuucugugac     1080

acuaugaacu cacucacacu uccaagcgaa guaaaccuau gcaacguaga uauauuuaac     1140

ccuaaauacg acugcaaaau aaugacaagc aaaacagacg uuaguucauc aguaauuaca     1200

agucuaggcg caauaguguc augcuacgga aaaacaaaau gcaccgcauc caauaaaugc     1260

cgaggaauca uuaaaacauu cucaaacgga ugcgacuacg ucagcaauaa aggaguagac     1320

acuguuucug uaggaaacac ccuauacuau guaaacaaac aagaagguca aucacuauac     1380

guaaagggag aaccaauuau aaauuuuuac gaccccuuag uauuuccaag ugaugaauuu     1440

gacgcaucua uaagucaagu uaacgaaaaa auuaaccaau cacuugcauu uauaagaaaa     1500

ucagacgaac uacuccauaa uguaaacgca gguaaaucaa caacaaacau caugaucaca     1560

accauaauaa uaguaauaau uguaauauua cuaucacuaa uagcaguagg auuacuacuc     1620

uacugcaaag cuagaucuac cccggucaca cucucaaaag accaauuauc uggaauaaac     1680

aauauagcau ucagcaacua aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7756
<211>  1980
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7756
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agccaacgcc      120

auaaccacca uccucaccgc cgucaccuuc ugcuucgcuu cuggccaaaa cauaaccgaa      180

gaguucuacc aauccacgug cucugccgug ucaaaaggcu accucggagc ccuccgcaca      240

gggugguaca cuuccgucau caccaucgaa cucucuaaca ucaaagaaau caagugcaac      300

ggcacagacg cgaaagucaa gcucaucaaa caagaacuag acaaauacaa aaacgccgua      360

acagaccucc aacuccuaau gcaguccaca ccagccacag gcuccggcag cgccaucgcc      420

uccggcgucg cugucugcaa aguccuacac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccuua gcaccaacaa agcagucguc ucuuuaagcg ggugcggagu cucuguccua      540

accuuuaaag uacucgaccu caaaaacuac aucgacaaac aacuacuacc aauacuaaac      600

aaacagagcu gcuccauucc caacaucgaa accguuaucg aguuccaaca aaagaacaac      660

cgccuccucg aaaucacccg cgaguucucc gucaacgcag gcgucaccac cccagucucc      720

accuauaugc uaaccaacag cgaacuccuc agccucauca augacaugcc aaucaccaac      780

gaccaaaaga aacucauguc caacaacgua cagauagucc gccagcaguc cuacagcauc      840

augugcauca ucaaagaaga agugcucgcc uacgugguac aacucccucu cuacggaguc      900

auugauacac ccugcuggaa acuccacaca agcccccucu gcacuacaaa caccaaagaa      960

ggcucuaaca uaugccucac ccgcacagac cgugguuggu acugcgacaa cgccggcucc     1020

guauccuucu uuccacaagc ugaaaccugc aaaguucaau caaaccgagu cuucugcgac     1080

accaugaacu cccucacauu gcccagcgaa gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaaaau caugaccucc aaaaccgacg ucagcuccag cgugaucaca     1200

agccuaggcg cgaucgucag cugcuacggc aaaaccaaau gcacagccuc caacaaaugc     1260

cgcggaauca uaaaaacauu caguaacggc ugcgacuacg uguccaauaa aggagucgac     1320

accguauccg ucggaaacac ccucuacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccauuau caacuucuac gacccccuag uuuuccccuc cgacgaguuc     1440

gacgcaagca uuucccaagu caacgaaaag aucaaucaau cccucgccuu cauacgcaaa     1500

agcgacgaac uacuacacaa cguaaacgcc ggcaaaagca ccaccaacau caugaucaca     1560

acaaucauca ucgucaucau cgucauccua cucucacuca ucgccguugg ccuacuacuc     1620

uacugcaaag cccgcuccac acccgucacc cucucaaaag accaacucuc cggcaucaac     1680

aacaucgcau ucagcaacug aggacuagua cuggcugcau cucccuuucc ucuguccucc     1740

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc     1800

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1920

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1980


<210>  7757
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7757
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7758
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7758
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccgguccac ccccgugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7759
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7759
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7760
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7760
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcucaac acccgugacc cugaguaaag aucaacucuc uggaaucaau     1680

aacauugcuu ucagcaauug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7761
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7761
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7762
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7762
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaagcac acccgugacc cuuucuaaag aucaacucuc cggcaucaau     1680

aacaucgcgu ucagcaauug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7763
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7763
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaacgca      120

aucacaacua uacuaacagc aguaacauuc ugcuuugccu caggucaaaa cauaacagag      180

gaauuuuacc aauccacaug cucugcugua agcaaaggau accucggagc auuaagaacu      240

ggaugguaca ccucaguaau aacuauagaa cuaucaaaca uaaaagaaau aaaauguaau      300

ggcacagacg caaaagugaa auuaaucaaa caagaacucg auaaauacaa aaaugccgua      360

accgaucucc aacuuuuaau gcaaagcaca cccgcaacag guuccggguc agcaauagca      420

agcggaguug caguaugcaa aguacuacac uuagaaggag aaguaaauaa aaucaaauca      480

gccuuacuau caacaaauaa agcaguugua ucacucucag gaugcggagu auccguacua      540

acauuuaaag uacuagaucu aaaaaacuac auagauaaac aacucuuacc aauacuaaau      600

aaacaaucau guuccauacc caacauagaa accguuaucg aauuucaaca aaaaaacaac      660

agauuacuag aaaucacacg agaauuuuca guaaaugcug gagucacaac accaguuagu      720

acauacaugc ucaccaauuc agaacuacua aguuuaauua acgauaugcc aauaacaaac      780

gaccaaaaaa aacuaauguc aaauaacgua caaauaguaa gacaacaauc auacucaauc      840

augugcauaa uaaaagaaga aguacuagcc uauguagucc aauuaccacu cuacggcgua      900

aucgacaccc caugcuggaa auuacacaca agcccauuau gcaccaccaa cacaaaagaa      960

gguucaaaca uuugcuuaac cagaaccgau cgaggauggu acugcgauaa cgcaggaucu     1020

gucuccuuuu ucccacaagc cgaaacaugc aaaguucaau caaaccgagu uuucugugac     1080

acuaugaacu cacucacacu uccaagcgaa guaaaccuau gcaacguaga uauauuuaac     1140

ccuaaauacg acugcaaaau aaugacaagc aaaacagacg uuaguucauc aguaauuaca     1200

agucuaggcg caauaguguc augcuacgga aaaacaaaau gcaccgcauc caauaaaugc     1260

cgaggaauca uuaaaacauu cucaaacgga ugcgacuacg ucagcaauaa aggaguagac     1320

acuguuucug uaggaaacac ccuauacuau guaaacaaac aagaagguca aucacuauac     1380

guaaagggag aaccaauuau aaauuuuuac gaccccuuag uauuuccaag ugaugaauuu     1440

gacgcaucua uaagucaagu uaacgaaaaa auuaaccaau cacuugcauu uauaagaaaa     1500

ucagacgaac uacuccauaa uguaaacgca gguaaaucaa caacaaacau caugaucaca     1560

accauaauaa uaguaauaau uguaauauua cuaucacuaa uagcaguagg auuacuacuc     1620

uacugcaaag cuagaucuac cccggucaca cucucaaaag accaauuauc uggaauaaac     1680

aauauagcau ucagcaacua aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7764
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7764
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agccaacgcc      120

auaaccacca uccucaccgc cgucaccuuc ugcuucgcuu cuggccaaaa cauaaccgaa      180

gaguucuacc aauccacgug cucugccgug ucaaaaggcu accucggagc ccuccgcaca      240

gggugguaca cuuccgucau caccaucgaa cucucuaaca ucaaagaaau caagugcaac      300

ggcacagacg cgaaagucaa gcucaucaaa caagaacuag acaaauacaa aaacgccgua      360

acagaccucc aacuccuaau gcaguccaca ccagccacag gcuccggcag cgccaucgcc      420

uccggcgucg cugucugcaa aguccuacac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccuua gcaccaacaa agcagucguc ucuuuaagcg ggugcggagu cucuguccua      540

accuuuaaag uacucgaccu caaaaacuac aucgacaaac aacuacuacc aauacuaaac      600

aaacagagcu gcuccauucc caacaucgaa accguuaucg aguuccaaca aaagaacaac      660

cgccuccucg aaaucacccg cgaguucucc gucaacgcag gcgucaccac cccagucucc      720

accuauaugc uaaccaacag cgaacuccuc agccucauca augacaugcc aaucaccaac      780

gaccaaaaga aacucauguc caacaacgua cagauagucc gccagcaguc cuacagcauc      840

augugcauca ucaaagaaga agugcucgcc uacgugguac aacucccucu cuacggaguc      900

auugauacac ccugcuggaa acuccacaca agcccccucu gcacuacaaa caccaaagaa      960

ggcucuaaca uaugccucac ccgcacagac cgugguuggu acugcgacaa cgccggcucc     1020

guauccuucu uuccacaagc ugaaaccugc aaaguucaau caaaccgagu cuucugcgac     1080

accaugaacu cccucacauu gcccagcgaa gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaaaau caugaccucc aaaaccgacg ucagcuccag cgugaucaca     1200

agccuaggcg cgaucgucag cugcuacggc aaaaccaaau gcacagccuc caacaaaugc     1260

cgcggaauca uaaaaacauu caguaacggc ugcgacuacg uguccaauaa aggagucgac     1320

accguauccg ucggaaacac ccucuacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccauuau caacuucuac gacccccuag uuuuccccuc cgacgaguuc     1440

gacgcaagca uuucccaagu caacgaaaag aucaaucaau cccucgccuu cauacgcaaa     1500

agcgacgaac uacuacacaa cguaaacgcc ggcaaaagca ccaccaacau caugaucaca     1560

acaaucauca ucgucaucau cgucauccua cucucacuca ucgccguugg ccuacuacuc     1620

uacugcaaag cccgcuccac acccgucacc cucucaaaag accaacucuc cggcaucaac     1680

aacaucgcau ucagcaacug aggacuagug aagggaacac ccaaauuuaa uucagccuua     1740

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc     1800

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1860

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1920

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1980

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     2040

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7765
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7765
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggagcac gcccgucacc cuguccaagg accagcugag cggcaucaac     1680

aacaucgcgu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7766
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7766
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccgguccac ccccgugacc cugagcaagg accagcucuc cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7767
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7767
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcuccac ccccgucacc cucuccaagg accagcucuc cggcaucaac     1680

aacaucgccu ucuccaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7768
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7768
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcucaac acccgugacc cugaguaaag aucaacucuc uggaaucaau     1680

aacauugcuu ucagcaauug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7769
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7769
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaagcac ccccgugacc cugagcaagg accagcugag cggcaucaac     1680

aacaucgccu ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7770
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7770
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaagcac acccgugacc cuuucuaaag aucaacucuc cggcaucaau     1680

aacaucgcgu ucagcaauug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7771
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7771
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuau uaauauuaaa agcaaacgca      120

aucacaacua uacuaacagc aguaacauuc ugcuuugccu caggucaaaa cauaacagag      180

gaauuuuacc aauccacaug cucugcugua agcaaaggau accucggagc auuaagaacu      240

ggaugguaca ccucaguaau aacuauagaa cuaucaaaca uaaaagaaau aaaauguaau      300

ggcacagacg caaaagugaa auuaaucaaa caagaacucg auaaauacaa aaaugccgua      360

accgaucucc aacuuuuaau gcaaagcaca cccgcaacag guuccggguc agcaauagca      420

agcggaguug caguaugcaa aguacuacac uuagaaggag aaguaaauaa aaucaaauca      480

gccuuacuau caacaaauaa agcaguugua ucacucucag gaugcggagu auccguacua      540

acauuuaaag uacuagaucu aaaaaacuac auagauaaac aacucuuacc aauacuaaau      600

aaacaaucau guuccauacc caacauagaa accguuaucg aauuucaaca aaaaaacaac      660

agauuacuag aaaucacacg agaauuuuca guaaaugcug gagucacaac accaguuagu      720

acauacaugc ucaccaauuc agaacuacua aguuuaauua acgauaugcc aauaacaaac      780

gaccaaaaaa aacuaauguc aaauaacgua caaauaguaa gacaacaauc auacucaauc      840

augugcauaa uaaaagaaga aguacuagcc uauguagucc aauuaccacu cuacggcgua      900

aucgacaccc caugcuggaa auuacacaca agcccauuau gcaccaccaa cacaaaagaa      960

gguucaaaca uuugcuuaac cagaaccgau cgaggauggu acugcgauaa cgcaggaucu     1020

gucuccuuuu ucccacaagc cgaaacaugc aaaguucaau caaaccgagu uuucugugac     1080

acuaugaacu cacucacacu uccaagcgaa guaaaccuau gcaacguaga uauauuuaac     1140

ccuaaauacg acugcaaaau aaugacaagc aaaacagacg uuaguucauc aguaauuaca     1200

agucuaggcg caauaguguc augcuacgga aaaacaaaau gcaccgcauc caauaaaugc     1260

cgaggaauca uuaaaacauu cucaaacgga ugcgacuacg ucagcaauaa aggaguagac     1320

acuguuucug uaggaaacac ccuauacuau guaaacaaac aagaagguca aucacuauac     1380

guaaagggag aaccaauuau aaauuuuuac gaccccuuag uauuuccaag ugaugaauuu     1440

gacgcaucua uaagucaagu uaacgaaaaa auuaaccaau cacuugcauu uauaagaaaa     1500

ucagacgaac uacuccauaa uguaaacgca gguaaaucaa caacaaacau caugaucaca     1560

accauaauaa uaguaauaau uguaauauua cuaucacuaa uagcaguagg auuacuacuc     1620

uacugcaaag cuagaucuac cccggucaca cucucaaaag accaauuauc uggaauaaac     1680

aauauagcau ucagcaacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7772
<211>  1976
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7772
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccuuaa agccaacgcc      120

auaaccacca uccucaccgc cgucaccuuc ugcuucgcuu cuggccaaaa cauaaccgaa      180

gaguucuacc aauccacgug cucugccgug ucaaaaggcu accucggagc ccuccgcaca      240

gggugguaca cuuccgucau caccaucgaa cucucuaaca ucaaagaaau caagugcaac      300

ggcacagacg cgaaagucaa gcucaucaaa caagaacuag acaaauacaa aaacgccgua      360

acagaccucc aacuccuaau gcaguccaca ccagccacag gcuccggcag cgccaucgcc      420

uccggcgucg cugucugcaa aguccuacac cucgaaggcg aagucaacaa aaucaaguca      480

gcccuccuua gcaccaacaa agcagucguc ucuuuaagcg ggugcggagu cucuguccua      540

accuuuaaag uacucgaccu caaaaacuac aucgacaaac aacuacuacc aauacuaaac      600

aaacagagcu gcuccauucc caacaucgaa accguuaucg aguuccaaca aaagaacaac      660

cgccuccucg aaaucacccg cgaguucucc gucaacgcag gcgucaccac cccagucucc      720

accuauaugc uaaccaacag cgaacuccuc agccucauca augacaugcc aaucaccaac      780

gaccaaaaga aacucauguc caacaacgua cagauagucc gccagcaguc cuacagcauc      840

augugcauca ucaaagaaga agugcucgcc uacgugguac aacucccucu cuacggaguc      900

auugauacac ccugcuggaa acuccacaca agcccccucu gcacuacaaa caccaaagaa      960

ggcucuaaca uaugccucac ccgcacagac cgugguuggu acugcgacaa cgccggcucc     1020

guauccuucu uuccacaagc ugaaaccugc aaaguucaau caaaccgagu cuucugcgac     1080

accaugaacu cccucacauu gcccagcgaa gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaaaau caugaccucc aaaaccgacg ucagcuccag cgugaucaca     1200

agccuaggcg cgaucgucag cugcuacggc aaaaccaaau gcacagccuc caacaaaugc     1260

cgcggaauca uaaaaacauu caguaacggc ugcgacuacg uguccaauaa aggagucgac     1320

accguauccg ucggaaacac ccucuacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccauuau caacuucuac gacccccuag uuuuccccuc cgacgaguuc     1440

gacgcaagca uuucccaagu caacgaaaag aucaaucaau cccucgccuu cauacgcaaa     1500

agcgacgaac uacuacacaa cguaaacgcc ggcaaaagca ccaccaacau caugaucaca     1560

acaaucauca ucgucaucau cgucauccua cucucacuca ucgccguugg ccuacuacuc     1620

uacugcaaag cccgcuccac acccgucacc cucucaaaag accaacucuc cggcaucaac     1680

aacaucgcau ucagcaacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau     1740

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg     1800

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1920

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1976


<210>  7773
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7773
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7774
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7774
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7775
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7775
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7776
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7776
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcucaacacc cgugacccug aguaaagauc aacucucugg aaucaauaac auugcuuuca     1680

gcaauugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7777
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7777
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7778
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7778
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaagcacacc cgugacccuu ucuaaagauc aacucuccgg caucaauaac aucgcguuca     1680

gcaauugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7779
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7779
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac      120

uaacagcagu aacauucugc uuugccucag gucaaaacau aacagaggaa uuuuaccaau      180

ccacaugcuc ugcuguaagc aaaggauacc ucggagcauu aagaacugga ugguacaccu      240

caguaauaac uauagaacua ucaaacauaa aagaaauaaa auguaauggc acagacgcaa      300

aagugaaauu aaucaaacaa gaacucgaua aauacaaaaa ugccguaacc gaucuccaac      360

uuuuaaugca aagcacaccc gcaacagguu ccgggucagc aauagcaagc ggaguugcag      420

uaugcaaagu acuacacuua gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa      480

caaauaaagc aguuguauca cucucaggau gcggaguauc cguacuaaca uuuaaaguac      540

uagaucuaaa aaacuacaua gauaaacaac ucuuaccaau acuaaauaaa caaucauguu      600

ccauacccaa cauagaaacc guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa      660

ucacacgaga auuuucagua aaugcuggag ucacaacacc aguuaguaca uacaugcuca      720

ccaauucaga acuacuaagu uuaauuaacg auaugccaau aacaaacgac caaaaaaaac      780

uaaugucaaa uaacguacaa auaguaagac aacaaucaua cucaaucaug ugcauaauaa      840

aagaagaagu acuagccuau guaguccaau uaccacucua cggcguaauc gacaccccau      900

gcuggaaauu acacacaagc ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu      960

gcuuaaccag aaccgaucga ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc     1020

cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacacu augaacucac     1080

ucacacuucc aagcgaagua aaccuaugca acguagauau auuuaacccu aaauacgacu     1140

gcaaaauaau gacaagcaaa acagacguua guucaucagu aauuacaagu cuaggcgcaa     1200

uagugucaug cuacggaaaa acaaaaugca ccgcauccaa uaaaugccga ggaaucauua     1260

aaacauucuc aaacggaugc gacuacguca gcaauaaagg aguagacacu guuucuguag     1320

gaaacacccu auacuaugua aacaaacaag aaggucaauc acuauacgua aagggagaac     1380

caauuauaaa uuuuuacgac cccuuaguau uuccaaguga ugaauuugac gcaucuauaa     1440

gucaaguuaa cgaaaaaauu aaccaaucac uugcauuuau aagaaaauca gacgaacuac     1500

uccauaaugu aaacgcaggu aaaucaacaa caaacaucau gaucacaacc auaauaauag     1560

uaauaauugu aauauuacua ucacuaauag caguaggauu acuacucuac ugcaaagcua     1620

gaucuacccc ggucacacuc ucaaaagacc aauuaucugg aauaaacaau auagcauuca     1680

gcaacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7780
<211>  1967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7780
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc caacgccaua accaccaucc      120

ucaccgccgu caccuucugc uucgcuucug gccaaaacau aaccgaagag uucuaccaau      180

ccacgugcuc ugccguguca aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu      240

ccgucaucac caucgaacuc ucuaacauca aagaaaucaa gugcaacggc acagacgcga      300

aagucaagcu caucaaacaa gaacuagaca aauacaaaaa cgccguaaca gaccuccaac      360

uccuaaugca guccacacca gccacaggcu ccggcagcgc caucgccucc ggcgucgcug      420

ucugcaaagu ccuacaccuc gaaggcgaag ucaacaaaau caagucagcc cuccuuagca      480

ccaacaaagc agucgucucu uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac      540

ucgaccucaa aaacuacauc gacaaacaac uacuaccaau acuaaacaaa cagagcugcu      600

ccauucccaa caucgaaacc guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucuccguc aacgcaggcg ucaccacccc agucuccacc uauaugcuaa      720

ccaacagcga acuccucagc cucaucaaug acaugccaau caccaacgac caaaagaaac      780

ucauguccaa caacguacag auaguccgcc agcaguccua cagcaucaug ugcaucauca      840

aagaagaagu gcucgccuac gugguacaac ucccucucua cggagucauu gauacacccu      900

gcuggaaacu ccacacaagc ccccucugca cuacaaacac caaagaaggc ucuaacauau      960

gccucacccg cacagaccgu gguugguacu gcgacaacgc cggcuccgua uccuucuuuc     1020

cacaagcuga aaccugcaaa guucaaucaa accgagucuu cugcgacacc augaacuccc     1080

ucacauugcc cagcgaaguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaaaaucau gaccuccaaa accgacguca gcuccagcgu gaucacaagc cuaggcgcga     1200

ucgucagcug cuacggcaaa accaaaugca cagccuccaa caaaugccgc ggaaucauaa     1260

aaacauucag uaacggcugc gacuacgugu ccaauaaagg agucgacacc guauccgucg     1320

gaaacacccu cuacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccauuaucaa cuucuacgac ccccuaguuu uccccuccga cgaguucgac gcaagcauuu     1440

cccaagucaa cgaaaagauc aaucaauccc ucgccuucau acgcaaaagc gacgaacuac     1500

uacacaacgu aaacgccggc aaaagcacca ccaacaucau gaucacaaca aucaucaucg     1560

ucaucaucgu cauccuacuc ucacucaucg ccguuggccu acuacucuac ugcaaagccc     1620

gcuccacacc cgucacccuc ucaaaagacc aacucuccgg caucaacaac aucgcauuca     1680

gcaacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag     1740

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu     1800

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1920

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1967


<210>  7781
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7781
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggagcacgcc cgucacccug uccaaggacc agcugagcgg caucaacaac aucgcguucu     1680

ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7782
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7782
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

gguccacccc cgugacccug agcaaggacc agcucuccgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7783
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7783
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcuccacccc cgucacccuc uccaaggacc agcucuccgg caucaacaac aucgccuucu     1680

ccaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7784
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7784
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcucaacacc cgugacccug aguaaagauc aacucucugg aaucaauaac auugcuuuca     1680

gcaauugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7785
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7785
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaagcacccc cgugacccug agcaaggacc agcugagcgg caucaacaac aucgccuuca     1680

gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7786
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7786
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaagcacacc cgugacccuu ucuaaagauc aacucuccgg caucaauaac aucgcguuca     1680

gcaauugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7787
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7787
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac      120

uaacagcagu aacauucugc uuugccucag gucaaaacau aacagaggaa uuuuaccaau      180

ccacaugcuc ugcuguaagc aaaggauacc ucggagcauu aagaacugga ugguacaccu      240

caguaauaac uauagaacua ucaaacauaa aagaaauaaa auguaauggc acagacgcaa      300

aagugaaauu aaucaaacaa gaacucgaua aauacaaaaa ugccguaacc gaucuccaac      360

uuuuaaugca aagcacaccc gcaacagguu ccgggucagc aauagcaagc ggaguugcag      420

uaugcaaagu acuacacuua gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa      480

caaauaaagc aguuguauca cucucaggau gcggaguauc cguacuaaca uuuaaaguac      540

uagaucuaaa aaacuacaua gauaaacaac ucuuaccaau acuaaauaaa caaucauguu      600

ccauacccaa cauagaaacc guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa      660

ucacacgaga auuuucagua aaugcuggag ucacaacacc aguuaguaca uacaugcuca      720

ccaauucaga acuacuaagu uuaauuaacg auaugccaau aacaaacgac caaaaaaaac      780

uaaugucaaa uaacguacaa auaguaagac aacaaucaua cucaaucaug ugcauaauaa      840

aagaagaagu acuagccuau guaguccaau uaccacucua cggcguaauc gacaccccau      900

gcuggaaauu acacacaagc ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu      960

gcuuaaccag aaccgaucga ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc     1020

cacaagccga aacaugcaaa guucaaucaa accgaguuuu cugugacacu augaacucac     1080

ucacacuucc aagcgaagua aaccuaugca acguagauau auuuaacccu aaauacgacu     1140

gcaaaauaau gacaagcaaa acagacguua guucaucagu aauuacaagu cuaggcgcaa     1200

uagugucaug cuacggaaaa acaaaaugca ccgcauccaa uaaaugccga ggaaucauua     1260

aaacauucuc aaacggaugc gacuacguca gcaauaaagg aguagacacu guuucuguag     1320

gaaacacccu auacuaugua aacaaacaag aaggucaauc acuauacgua aagggagaac     1380

caauuauaaa uuuuuacgac cccuuaguau uuccaaguga ugaauuugac gcaucuauaa     1440

gucaaguuaa cgaaaaaauu aaccaaucac uugcauuuau aagaaaauca gacgaacuac     1500

uccauaaugu aaacgcaggu aaaucaacaa caaacaucau gaucacaacc auaauaauag     1560

uaauaauugu aauauuacua ucacuaauag caguaggauu acuacucuac ugcaaagcua     1620

gaucuacccc ggucacacuc ucaaaagacc aauuaucugg aauaaacaau auagcauuca     1680

gcaacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7788
<211>  2183
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7788
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccuuaaagc caacgccaua accaccaucc      120

ucaccgccgu caccuucugc uucgcuucug gccaaaacau aaccgaagag uucuaccaau      180

ccacgugcuc ugccguguca aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu      240

ccgucaucac caucgaacuc ucuaacauca aagaaaucaa gugcaacggc acagacgcga      300

aagucaagcu caucaaacaa gaacuagaca aauacaaaaa cgccguaaca gaccuccaac      360

uccuaaugca guccacacca gccacaggcu ccggcagcgc caucgccucc ggcgucgcug      420

ucugcaaagu ccuacaccuc gaaggcgaag ucaacaaaau caagucagcc cuccuuagca      480

ccaacaaagc agucgucucu uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac      540

ucgaccucaa aaacuacauc gacaaacaac uacuaccaau acuaaacaaa cagagcugcu      600

ccauucccaa caucgaaacc guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa      660

ucacccgcga guucuccguc aacgcaggcg ucaccacccc agucuccacc uauaugcuaa      720

ccaacagcga acuccucagc cucaucaaug acaugccaau caccaacgac caaaagaaac      780

ucauguccaa caacguacag auaguccgcc agcaguccua cagcaucaug ugcaucauca      840

aagaagaagu gcucgccuac gugguacaac ucccucucua cggagucauu gauacacccu      900

gcuggaaacu ccacacaagc ccccucugca cuacaaacac caaagaaggc ucuaacauau      960

gccucacccg cacagaccgu gguugguacu gcgacaacgc cggcuccgua uccuucuuuc     1020

cacaagcuga aaccugcaaa guucaaucaa accgagucuu cugcgacacc augaacuccc     1080

ucacauugcc cagcgaaguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaaaaucau gaccuccaaa accgacguca gcuccagcgu gaucacaagc cuaggcgcga     1200

ucgucagcug cuacggcaaa accaaaugca cagccuccaa caaaugccgc ggaaucauaa     1260

aaacauucag uaacggcugc gacuacgugu ccaauaaagg agucgacacc guauccgucg     1320

gaaacacccu cuacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccauuaucaa cuucuacgac ccccuaguuu uccccuccga cgaguucgac gcaagcauuu     1440

cccaagucaa cgaaaagauc aaucaauccc ucgccuucau acgcaaaagc gacgaacuac     1500

uacacaacgu aaacgccggc aaaagcacca ccaacaucau gaucacaaca aucaucaucg     1560

ucaucaucgu cauccuacuc ucacucaucg ccguuggccu acuacucuac ugcaaagccc     1620

gcuccacacc cgucacccuc ucaaaagacc aacucuccgg caucaacaac aucgcauuca     1680

gcaacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu     1740

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg     1800

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1860

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1920

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1980

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     2040

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     2160

cucuuuucag agccaccaga auu                                             2183


<210>  7789
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7789
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7790
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7790
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccgguccacc     1620

cccgugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7791
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7791
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7792
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7792
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcucaaca     1620

cccgugaccc ugaguaaaga ucaacucucu ggaaucaaua acauugcuuu cagcaauuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7793
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7793
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7794
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7794
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaagcaca     1620

cccgugaccc uuucuaaaga ucaacucucc ggcaucaaua acaucgcguu cagcaauuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7795
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7795
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaacgcaa ucacaacuau acuaacagca      120

guaacauucu gcuuugccuc aggucaaaac auaacagagg aauuuuacca auccacaugc      180

ucugcuguaa gcaaaggaua ccucggagca uuaagaacug gaugguacac cucaguaaua      240

acuauagaac uaucaaacau aaaagaaaua aaauguaaug gcacagacgc aaaagugaaa      300

uuaaucaaac aagaacucga uaaauacaaa aaugccguaa ccgaucucca acuuuuaaug      360

caaagcacac ccgcaacagg uuccggguca gcaauagcaa gcggaguugc aguaugcaaa      420

guacuacacu uagaaggaga aguaaauaaa aucaaaucag ccuuacuauc aacaaauaaa      480

gcaguuguau cacucucagg augcggagua uccguacuaa cauuuaaagu acuagaucua      540

aaaaacuaca uagauaaaca acucuuacca auacuaaaua aacaaucaug uuccauaccc      600

aacauagaaa ccguuaucga auuucaacaa aaaaacaaca gauuacuaga aaucacacga      660

gaauuuucag uaaaugcugg agucacaaca ccaguuagua cauacaugcu caccaauuca      720

gaacuacuaa guuuaauuaa cgauaugcca auaacaaacg accaaaaaaa acuaauguca      780

aauaacguac aaauaguaag acaacaauca uacucaauca ugugcauaau aaaagaagaa      840

guacuagccu auguagucca auuaccacuc uacggcguaa ucgacacccc augcuggaaa      900

uuacacacaa gcccauuaug caccaccaac acaaaagaag guucaaacau uugcuuaacc      960

agaaccgauc gaggauggua cugcgauaac gcaggaucug ucuccuuuuu cccacaagcc     1020

gaaacaugca aaguucaauc aaaccgaguu uucugugaca cuaugaacuc acucacacuu     1080

ccaagcgaag uaaaccuaug caacguagau auauuuaacc cuaaauacga cugcaaaaua     1140

augacaagca aaacagacgu uaguucauca guaauuacaa gucuaggcgc aauaguguca     1200

ugcuacggaa aaacaaaaug caccgcaucc aauaaaugcc gaggaaucau uaaaacauuc     1260

ucaaacggau gcgacuacgu cagcaauaaa ggaguagaca cuguuucugu aggaaacacc     1320

cuauacuaug uaaacaaaca agaaggucaa ucacuauacg uaaagggaga accaauuaua     1380

aauuuuuacg accccuuagu auuuccaagu gaugaauuug acgcaucuau aagucaaguu     1440

aacgaaaaaa uuaaccaauc acuugcauuu auaagaaaau cagacgaacu acuccauaau     1500

guaaacgcag guaaaucaac aacaaacauc augaucacaa ccauaauaau aguaauaauu     1560

guaauauuac uaucacuaau agcaguagga uuacuacucu acugcaaagc uagaucuacc     1620

ccggucacac ucucaaaaga ccaauuaucu ggaauaaaca auauagcauu cagcaacuaa     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7796
<211>  1959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7796
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gccaacgcca uaaccaccau ccucaccgcc      120

gucaccuucu gcuucgcuuc uggccaaaac auaaccgaag aguucuacca auccacgugc      180

ucugccgugu caaaaggcua ccucggagcc cuccgcacag ggugguacac uuccgucauc      240

accaucgaac ucucuaacau caaagaaauc aagugcaacg gcacagacgc gaaagucaag      300

cucaucaaac aagaacuaga caaauacaaa aacgccguaa cagaccucca acuccuaaug      360

caguccacac cagccacagg cuccggcagc gccaucgccu ccggcgucgc ugucugcaaa      420

guccuacacc ucgaaggcga agucaacaaa aucaagucag cccuccuuag caccaacaaa      480

gcagucgucu cuuuaagcgg gugcggaguc ucuguccuaa ccuuuaaagu acucgaccuc      540

aaaaacuaca ucgacaaaca acuacuacca auacuaaaca aacagagcug cuccauuccc      600

aacaucgaaa ccguuaucga guuccaacaa aagaacaacc gccuccucga aaucacccgc      660

gaguucuccg ucaacgcagg cgucaccacc ccagucucca ccuauaugcu aaccaacagc      720

gaacuccuca gccucaucaa ugacaugcca aucaccaacg accaaaagaa acucaugucc      780

aacaacguac agauaguccg ccagcagucc uacagcauca ugugcaucau caaagaagaa      840

gugcucgccu acgugguaca acucccucuc uacggaguca uugauacacc cugcuggaaa      900

cuccacacaa gcccccucug cacuacaaac accaaagaag gcucuaacau augccucacc      960

cgcacagacc gugguuggua cugcgacaac gccggcuccg uauccuucuu uccacaagcu     1020

gaaaccugca aaguucaauc aaaccgaguc uucugcgaca ccaugaacuc ccucacauug     1080

cccagcgaag ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaaaauc     1140

augaccucca aaaccgacgu cagcuccagc gugaucacaa gccuaggcgc gaucgucagc     1200

ugcuacggca aaaccaaaug cacagccucc aacaaaugcc gcggaaucau aaaaacauuc     1260

aguaacggcu gcgacuacgu guccaauaaa ggagucgaca ccguauccgu cggaaacacc     1320

cucuacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccauuauc     1380

aacuucuacg acccccuagu uuuccccucc gacgaguucg acgcaagcau uucccaaguc     1440

aacgaaaaga ucaaucaauc ccucgccuuc auacgcaaaa gcgacgaacu acuacacaac     1500

guaaacgccg gcaaaagcac caccaacauc augaucacaa caaucaucau cgucaucauc     1560

gucauccuac ucucacucau cgccguuggc cuacuacucu acugcaaagc ccgcuccaca     1620

cccgucaccc ucucaaaaga ccaacucucc ggcaucaaca acaucgcauu cagcaacuga     1680

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga     1740

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1800

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1920

cccccccccc caaaggcucu uuucagagcc accagaauu                            1959


<210>  7797
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7797
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggagcacg     1620

cccgucaccc uguccaagga ccagcugagc ggcaucaaca acaucgcguu cuccaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7798
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7798
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccgguccacc     1620

cccgugaccc ugagcaagga ccagcucucc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7799
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7799
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcuccacc     1620

cccgucaccc ucuccaagga ccagcucucc ggcaucaaca acaucgccuu cuccaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7800
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7800
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcucaaca     1620

cccgugaccc ugaguaaaga ucaacucucu ggaaucaaua acauugcuuu cagcaauuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7801
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7801
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaagcacc     1620

cccgugaccc ugagcaagga ccagcugagc ggcaucaaca acaucgccuu cagcaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7802
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7802
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaagcaca     1620

cccgugaccc uuucuaaaga ucaacucucc ggcaucaaua acaucgcguu cagcaauuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7803
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7803
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuauu aauauuaaaa gcaaacgcaa ucacaacuau acuaacagca      120

guaacauucu gcuuugccuc aggucaaaac auaacagagg aauuuuacca auccacaugc      180

ucugcuguaa gcaaaggaua ccucggagca uuaagaacug gaugguacac cucaguaaua      240

acuauagaac uaucaaacau aaaagaaaua aaauguaaug gcacagacgc aaaagugaaa      300

uuaaucaaac aagaacucga uaaauacaaa aaugccguaa ccgaucucca acuuuuaaug      360

caaagcacac ccgcaacagg uuccggguca gcaauagcaa gcggaguugc aguaugcaaa      420

guacuacacu uagaaggaga aguaaauaaa aucaaaucag ccuuacuauc aacaaauaaa      480

gcaguuguau cacucucagg augcggagua uccguacuaa cauuuaaagu acuagaucua      540

aaaaacuaca uagauaaaca acucuuacca auacuaaaua aacaaucaug uuccauaccc      600

aacauagaaa ccguuaucga auuucaacaa aaaaacaaca gauuacuaga aaucacacga      660

gaauuuucag uaaaugcugg agucacaaca ccaguuagua cauacaugcu caccaauuca      720

gaacuacuaa guuuaauuaa cgauaugcca auaacaaacg accaaaaaaa acuaauguca      780

aauaacguac aaauaguaag acaacaauca uacucaauca ugugcauaau aaaagaagaa      840

guacuagccu auguagucca auuaccacuc uacggcguaa ucgacacccc augcuggaaa      900

uuacacacaa gcccauuaug caccaccaac acaaaagaag guucaaacau uugcuuaacc      960

agaaccgauc gaggauggua cugcgauaac gcaggaucug ucuccuuuuu cccacaagcc     1020

gaaacaugca aaguucaauc aaaccgaguu uucugugaca cuaugaacuc acucacacuu     1080

ccaagcgaag uaaaccuaug caacguagau auauuuaacc cuaaauacga cugcaaaaua     1140

augacaagca aaacagacgu uaguucauca guaauuacaa gucuaggcgc aauaguguca     1200

ugcuacggaa aaacaaaaug caccgcaucc aauaaaugcc gaggaaucau uaaaacauuc     1260

ucaaacggau gcgacuacgu cagcaauaaa ggaguagaca cuguuucugu aggaaacacc     1320

cuauacuaug uaaacaaaca agaaggucaa ucacuauacg uaaagggaga accaauuaua     1380

aauuuuuacg accccuuagu auuuccaagu gaugaauuug acgcaucuau aagucaaguu     1440

aacgaaaaaa uuaaccaauc acuugcauuu auaagaaaau cagacgaacu acuccauaau     1500

guaaacgcag guaaaucaac aacaaacauc augaucacaa ccauaauaau aguaauaauu     1560

guaauauuac uaucacuaau agcaguagga uuacuacucu acugcaaagc uagaucuacc     1620

ccggucacac ucucaaaaga ccaauuaucu ggaauaaaca auauagcauu cagcaacuaa     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7804
<211>  1955
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7804
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccuuaaa gccaacgcca uaaccaccau ccucaccgcc      120

gucaccuucu gcuucgcuuc uggccaaaac auaaccgaag aguucuacca auccacgugc      180

ucugccgugu caaaaggcua ccucggagcc cuccgcacag ggugguacac uuccgucauc      240

accaucgaac ucucuaacau caaagaaauc aagugcaacg gcacagacgc gaaagucaag      300

cucaucaaac aagaacuaga caaauacaaa aacgccguaa cagaccucca acuccuaaug      360

caguccacac cagccacagg cuccggcagc gccaucgccu ccggcgucgc ugucugcaaa      420

guccuacacc ucgaaggcga agucaacaaa aucaagucag cccuccuuag caccaacaaa      480

gcagucgucu cuuuaagcgg gugcggaguc ucuguccuaa ccuuuaaagu acucgaccuc      540

aaaaacuaca ucgacaaaca acuacuacca auacuaaaca aacagagcug cuccauuccc      600

aacaucgaaa ccguuaucga guuccaacaa aagaacaacc gccuccucga aaucacccgc      660

gaguucuccg ucaacgcagg cgucaccacc ccagucucca ccuauaugcu aaccaacagc      720

gaacuccuca gccucaucaa ugacaugcca aucaccaacg accaaaagaa acucaugucc      780

aacaacguac agauaguccg ccagcagucc uacagcauca ugugcaucau caaagaagaa      840

gugcucgccu acgugguaca acucccucuc uacggaguca uugauacacc cugcuggaaa      900

cuccacacaa gcccccucug cacuacaaac accaaagaag gcucuaacau augccucacc      960

cgcacagacc gugguuggua cugcgacaac gccggcuccg uauccuucuu uccacaagcu     1020

gaaaccugca aaguucaauc aaaccgaguc uucugcgaca ccaugaacuc ccucacauug     1080

cccagcgaag ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaaaauc     1140

augaccucca aaaccgacgu cagcuccagc gugaucacaa gccuaggcgc gaucgucagc     1200

ugcuacggca aaaccaaaug cacagccucc aacaaaugcc gcggaaucau aaaaacauuc     1260

aguaacggcu gcgacuacgu guccaauaaa ggagucgaca ccguauccgu cggaaacacc     1320

cucuacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccauuauc     1380

aacuucuacg acccccuagu uuuccccucc gacgaguucg acgcaagcau uucccaaguc     1440

aacgaaaaga ucaaucaauc ccucgccuuc auacgcaaaa gcgacgaacu acuacacaac     1500

guaaacgccg gcaaaagcac caccaacauc augaucacaa caaucaucau cgucaucauc     1560

gucauccuac ucucacucau cgccguuggc cuacuacucu acugcaaagc ccgcuccaca     1620

cccgucaccc ucucaaaaga ccaacucucc ggcaucaaca acaucgcauu cagcaacuga     1680

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu     1740

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1800

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1920

cccccccaaa ggcucuuuuc agagccacca gaauu                                1955


<210>  7805
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7805
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7806
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7806
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7807
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7807
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7808
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7808
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cucaacaccc gugacccuga guaaagauca acucucugga     1680

aucaauaaca uugcuuucag caauugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7809
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7809
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7810
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7810
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag aagcacaccc gugacccuuu cuaaagauca acucuccggc     1680

aucaauaaca ucgcguucag caauugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7811
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7811
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aacgcaauca caacuauacu aacagcagua acauucugcu uugccucagg ucaaaacaua      180

acagaggaau uuuaccaauc cacaugcucu gcuguaagca aaggauaccu cggagcauua      240

agaacuggau gguacaccuc aguaauaacu auagaacuau caaacauaaa agaaauaaaa      300

uguaauggca cagacgcaaa agugaaauua aucaaacaag aacucgauaa auacaaaaau      360

gccguaaccg aucuccaacu uuuaaugcaa agcacacccg caacagguuc cgggucagca      420

auagcaagcg gaguugcagu augcaaagua cuacacuuag aaggagaagu aaauaaaauc      480

aaaucagccu uacuaucaac aaauaaagca guuguaucac ucucaggaug cggaguaucc      540

guacuaacau uuaaaguacu agaucuaaaa aacuacauag auaaacaacu cuuaccaaua      600

cuaaauaaac aaucauguuc cauacccaac auagaaaccg uuaucgaauu ucaacaaaaa      660

aacaacagau uacuagaaau cacacgagaa uuuucaguaa augcuggagu cacaacacca      720

guuaguacau acaugcucac caauucagaa cuacuaaguu uaauuaacga uaugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaagua cuagccuaug uaguccaauu accacucuac      900

ggcguaaucg acaccccaug cuggaaauua cacacaagcc cauuaugcac caccaacaca      960

aaagaagguu caaacauuug cuuaaccaga accgaucgag gaugguacug cgauaacgca     1020

ggaucugucu ccuuuuuccc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacua ugaacucacu cacacuucca agcgaaguaa accuaugcaa cguagauaua     1140

uuuaacccua aauacgacug caaaauaaug acaagcaaaa cagacguuag uucaucagua     1200

auuacaaguc uaggcgcaau agugucaugc uacggaaaaa caaaaugcac cgcauccaau     1260

aaaugccgag gaaucauuaa aacauucuca aacggaugcg acuacgucag caauaaagga     1320

guagacacug uuucuguagg aaacacccua uacuauguaa acaaacaaga aggucaauca     1380

cuauacguaa agggagaacc aauuauaaau uuuuacgacc ccuuaguauu uccaagugau     1440

gaauuugacg caucuauaag ucaaguuaac gaaaaaauua accaaucacu ugcauuuaua     1500

agaaaaucag acgaacuacu ccauaaugua aacgcaggua aaucaacaac aaacaucaug     1560

aucacaacca uaauaauagu aauaauugua auauuacuau cacuaauagc aguaggauua     1620

cuacucuacu gcaaagcuag aucuaccccg gucacacucu caaaagacca auuaucugga     1680

auaaacaaua uagcauucag caacuaagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7812
<211>  1970
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7812
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagcc      120

aacgccauaa ccaccauccu caccgccguc accuucugcu ucgcuucugg ccaaaacaua      180

accgaagagu ucuaccaauc cacgugcucu gccgugucaa aaggcuaccu cggagcccuc      240

cgcacagggu gguacacuuc cgucaucacc aucgaacucu cuaacaucaa agaaaucaag      300

ugcaacggca cagacgcgaa agucaagcuc aucaaacaag aacuagacaa auacaaaaac      360

gccguaacag accuccaacu ccuaaugcag uccacaccag ccacaggcuc cggcagcgcc      420

aucgccuccg gcgucgcugu cugcaaaguc cuacaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccuuagcac caacaaagca gucgucucuu uaagcgggug cggagucucu      540

guccuaaccu uuaaaguacu cgaccucaaa aacuacaucg acaaacaacu acuaccaaua      600

cuaaacaaac agagcugcuc cauucccaac aucgaaaccg uuaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccacccca      720

gucuccaccu auaugcuaac caacagcgaa cuccucagcc ucaucaauga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaga uaguccgcca gcaguccuac      840

agcaucaugu gcaucaucaa agaagaagug cucgccuacg ugguacaacu cccucucuac      900

ggagucauug auacacccug cuggaaacuc cacacaagcc cccucugcac uacaaacacc      960

aaagaaggcu cuaacauaug ccucacccgc acagaccgug guugguacug cgacaacgcc     1020

ggcuccguau ccuucuuucc acaagcugaa accugcaaag uucaaucaaa ccgagucuuc     1080

ugcgacacca ugaacucccu cacauugccc agcgaaguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caaaaucaug accuccaaaa ccgacgucag cuccagcgug     1200

aucacaagcc uaggcgcgau cgucagcugc uacggcaaaa ccaaaugcac agccuccaac     1260

aaaugccgcg gaaucauaaa aacauucagu aacggcugcg acuacguguc caauaaagga     1320

gucgacaccg uauccgucgg aaacacccuc uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc cauuaucaac uucuacgacc cccuaguuuu ccccuccgac     1440

gaguucgacg caagcauuuc ccaagucaac gaaaagauca aucaaucccu cgccuucaua     1500

cgcaaaagcg acgaacuacu acacaacgua aacgccggca aaagcaccac caacaucaug     1560

aucacaacaa ucaucaucgu caucaucguc auccuacucu cacucaucgc cguuggccua     1620

cuacucuacu gcaaagcccg cuccacaccc gucacccucu caaaagacca acucuccggc     1680

aucaacaaca ucgcauucag caacugagga cuaguaauaa ggaaacugua ugaaugucug     1740

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1800

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1920

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1970


<210>  7813
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7813
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gagcacgccc gucacccugu ccaaggacca gcugagcggc     1680

aucaacaaca ucgcguucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7814
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7814
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg guccaccccc gugacccuga gcaaggacca gcucuccggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7815
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7815
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cuccaccccc gucacccucu ccaaggacca gcucuccggc     1680

aucaacaaca ucgccuucuc caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7816
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7816
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cucaacaccc gugacccuga guaaagauca acucucugga     1680

aucaauaaca uugcuuucag caauugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7817
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7817
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag aagcaccccc gugacccuga gcaaggacca gcugagcggc     1680

aucaacaaca ucgccuucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7818
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7818
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag aagcacaccc gugacccuuu cuaaagauca acucuccggc     1680

aucaauaaca ucgcguucag caauugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7819
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7819
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuauuaau auuaaaagca      120

aacgcaauca caacuauacu aacagcagua acauucugcu uugccucagg ucaaaacaua      180

acagaggaau uuuaccaauc cacaugcucu gcuguaagca aaggauaccu cggagcauua      240

agaacuggau gguacaccuc aguaauaacu auagaacuau caaacauaaa agaaauaaaa      300

uguaauggca cagacgcaaa agugaaauua aucaaacaag aacucgauaa auacaaaaau      360

gccguaaccg aucuccaacu uuuaaugcaa agcacacccg caacagguuc cgggucagca      420

auagcaagcg gaguugcagu augcaaagua cuacacuuag aaggagaagu aaauaaaauc      480

aaaucagccu uacuaucaac aaauaaagca guuguaucac ucucaggaug cggaguaucc      540

guacuaacau uuaaaguacu agaucuaaaa aacuacauag auaaacaacu cuuaccaaua      600

cuaaauaaac aaucauguuc cauacccaac auagaaaccg uuaucgaauu ucaacaaaaa      660

aacaacagau uacuagaaau cacacgagaa uuuucaguaa augcuggagu cacaacacca      720

guuaguacau acaugcucac caauucagaa cuacuaaguu uaauuaacga uaugccaaua      780

acaaacgacc aaaaaaaacu aaugucaaau aacguacaaa uaguaagaca acaaucauac      840

ucaaucaugu gcauaauaaa agaagaagua cuagccuaug uaguccaauu accacucuac      900

ggcguaaucg acaccccaug cuggaaauua cacacaagcc cauuaugcac caccaacaca      960

aaagaagguu caaacauuug cuuaaccaga accgaucgag gaugguacug cgauaacgca     1020

ggaucugucu ccuuuuuccc acaagccgaa acaugcaaag uucaaucaaa ccgaguuuuc     1080

ugugacacua ugaacucacu cacacuucca agcgaaguaa accuaugcaa cguagauaua     1140

uuuaacccua aauacgacug caaaauaaug acaagcaaaa cagacguuag uucaucagua     1200

auuacaaguc uaggcgcaau agugucaugc uacggaaaaa caaaaugcac cgcauccaau     1260

aaaugccgag gaaucauuaa aacauucuca aacggaugcg acuacgucag caauaaagga     1320

guagacacug uuucuguagg aaacacccua uacuauguaa acaaacaaga aggucaauca     1380

cuauacguaa agggagaacc aauuauaaau uuuuacgacc ccuuaguauu uccaagugau     1440

gaauuugacg caucuauaag ucaaguuaac gaaaaaauua accaaucacu ugcauuuaua     1500

agaaaaucag acgaacuacu ccauaaugua aacgcaggua aaucaacaac aaacaucaug     1560

aucacaacca uaauaauagu aauaauugua auauuacuau cacuaauagc aguaggauua     1620

cuacucuacu gcaaagcuag aucuaccccg gucacacucu caaaagacca auuaucugga     1680

auaaacaaua uagcauucag caacuaagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7820
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7820
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccuuaaagcc      120

aacgccauaa ccaccauccu caccgccguc accuucugcu ucgcuucugg ccaaaacaua      180

accgaagagu ucuaccaauc cacgugcucu gccgugucaa aaggcuaccu cggagcccuc      240

cgcacagggu gguacacuuc cgucaucacc aucgaacucu cuaacaucaa agaaaucaag      300

ugcaacggca cagacgcgaa agucaagcuc aucaaacaag aacuagacaa auacaaaaac      360

gccguaacag accuccaacu ccuaaugcag uccacaccag ccacaggcuc cggcagcgcc      420

aucgccuccg gcgucgcugu cugcaaaguc cuacaccucg aaggcgaagu caacaaaauc      480

aagucagccc uccuuagcac caacaaagca gucgucucuu uaagcgggug cggagucucu      540

guccuaaccu uuaaaguacu cgaccucaaa aacuacaucg acaaacaacu acuaccaaua      600

cuaaacaaac agagcugcuc cauucccaac aucgaaaccg uuaucgaguu ccaacaaaag      660

aacaaccgcc uccucgaaau cacccgcgag uucuccguca acgcaggcgu caccacccca      720

gucuccaccu auaugcuaac caacagcgaa cuccucagcc ucaucaauga caugccaauc      780

accaacgacc aaaagaaacu cauguccaac aacguacaga uaguccgcca gcaguccuac      840

agcaucaugu gcaucaucaa agaagaagug cucgccuacg ugguacaacu cccucucuac      900

ggagucauug auacacccug cuggaaacuc cacacaagcc cccucugcac uacaaacacc      960

aaagaaggcu cuaacauaug ccucacccgc acagaccgug guugguacug cgacaacgcc     1020

ggcuccguau ccuucuuucc acaagcugaa accugcaaag uucaaucaaa ccgagucuuc     1080

ugcgacacca ugaacucccu cacauugccc agcgaaguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caaaaucaug accuccaaaa ccgacgucag cuccagcgug     1200

aucacaagcc uaggcgcgau cgucagcugc uacggcaaaa ccaaaugcac agccuccaac     1260

aaaugccgcg gaaucauaaa aacauucagu aacggcugcg acuacguguc caauaaagga     1320

gucgacaccg uauccgucgg aaacacccuc uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc cauuaucaac uucuacgacc cccuaguuuu ccccuccgac     1440

gaguucgacg caagcauuuc ccaagucaac gaaaagauca aucaaucccu cgccuucaua     1500

cgcaaaagcg acgaacuacu acacaacgua aacgccggca aaagcaccac caacaucaug     1560

aucacaacaa ucaucaucgu caucaucguc auccuacucu cacucaucgc cguuggccua     1620

cuacucuacu gcaaagcccg cuccacaccc gucacccucu caaaagacca acucuccggc     1680

aucaacaaca ucgcauucag caacugagga cuagugaagg gaacacccaa auuuaauuca     1740

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1800

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1860

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1920

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1980

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     2040

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7821
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7821
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc     1680

acccugucca aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7822
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7822
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccgguc cacccccgug     1680

acccugagca aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7823
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7823
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc     1680

acccucucca aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7824
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7824
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcuc aacacccgug     1680

acccugagua aagaucaacu cucuggaauc aauaacauug cuuucagcaa uugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7825
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7825
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug     1680

acccugagca aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7826
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7826
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaag cacacccgug     1680

acccuuucua aagaucaacu cuccggcauc aauaacaucg cguucagcaa uugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7827
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7827
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uauuaauauu aaaagcaaac gcaaucacaa cuauacuaac agcaguaaca      180

uucugcuuug ccucagguca aaacauaaca gaggaauuuu accaauccac augcucugcu      240

guaagcaaag gauaccucgg agcauuaaga acuggauggu acaccucagu aauaacuaua      300

gaacuaucaa acauaaaaga aauaaaaugu aauggcacag acgcaaaagu gaaauuaauc      360

aaacaagaac ucgauaaaua caaaaaugcc guaaccgauc uccaacuuuu aaugcaaagc      420

acacccgcaa cagguuccgg gucagcaaua gcaagcggag uugcaguaug caaaguacua      480

cacuuagaag gagaaguaaa uaaaaucaaa ucagccuuac uaucaacaaa uaaagcaguu      540

guaucacucu caggaugcgg aguauccgua cuaacauuua aaguacuaga ucuaaaaaac      600

uacauagaua aacaacucuu accaauacua aauaaacaau cauguuccau acccaacaua      660

gaaaccguua ucgaauuuca acaaaaaaac aacagauuac uagaaaucac acgagaauuu      720

ucaguaaaug cuggagucac aacaccaguu aguacauaca ugcucaccaa uucagaacua      780

cuaaguuuaa uuaacgauau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac      840

guacaaauag uaagacaaca aucauacuca aucaugugca uaauaaaaga agaaguacua      900

gccuauguag uccaauuacc acucuacggc guaaucgaca ccccaugcug gaaauuacac      960

acaagcccau uaugcaccac caacacaaaa gaagguucaa acauuugcuu aaccagaacc     1020

gaucgaggau gguacugcga uaacgcagga ucugucuccu uuuucccaca agccgaaaca     1080

ugcaaaguuc aaucaaaccg aguuuucugu gacacuauga acucacucac acuuccaagc     1140

gaaguaaacc uaugcaacgu agauauauuu aacccuaaau acgacugcaa aauaaugaca     1200

agcaaaacag acguuaguuc aucaguaauu acaagucuag gcgcaauagu gucaugcuac     1260

ggaaaaacaa aaugcaccgc auccaauaaa ugccgaggaa ucauuaaaac auucucaaac     1320

ggaugcgacu acgucagcaa uaaaggagua gacacuguuu cuguaggaaa cacccuauac     1380

uauguaaaca aacaagaagg ucaaucacua uacguaaagg gagaaccaau uauaaauuuu     1440

uacgaccccu uaguauuucc aagugaugaa uuugacgcau cuauaaguca aguuaacgaa     1500

aaaauuaacc aaucacuugc auuuauaaga aaaucagacg aacuacucca uaauguaaac     1560

gcagguaaau caacaacaaa caucaugauc acaaccauaa uaauaguaau aauuguaaua     1620

uuacuaucac uaauagcagu aggauuacua cucuacugca aagcuagauc uaccccgguc     1680

acacucucaa aagaccaauu aucuggaaua aacaauauag cauucagcaa cuaaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7828
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7828
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu uaaagccaac gccauaacca ccauccucac cgccgucacc      180

uucugcuucg cuucuggcca aaacauaacc gaagaguucu accaauccac gugcucugcc      240

gugucaaaag gcuaccucgg agcccuccgc acaggguggu acacuuccgu caucaccauc      300

gaacucucua acaucaaaga aaucaagugc aacggcacag acgcgaaagu caagcucauc      360

aaacaagaac uagacaaaua caaaaacgcc guaacagacc uccaacuccu aaugcagucc      420

acaccagcca caggcuccgg cagcgccauc gccuccggcg ucgcugucug caaaguccua      480

caccucgaag gcgaagucaa caaaaucaag ucagcccucc uuagcaccaa caaagcaguc      540

gucucuuuaa gcgggugcgg agucucuguc cuaaccuuua aaguacucga ccucaaaaac      600

uacaucgaca aacaacuacu accaauacua aacaaacaga gcugcuccau ucccaacauc      660

gaaaccguua ucgaguucca acaaaagaac aaccgccucc ucgaaaucac ccgcgaguuc      720

uccgucaacg caggcgucac caccccaguc uccaccuaua ugcuaaccaa cagcgaacuc      780

cucagccuca ucaaugacau gccaaucacc aacgaccaaa agaaacucau guccaacaac      840

guacagauag uccgccagca guccuacagc aucaugugca ucaucaaaga agaagugcuc      900

gccuacgugg uacaacuccc ucucuacgga gucauugaua cacccugcug gaaacuccac      960

acaagccccc ucugcacuac aaacaccaaa gaaggcucua acauaugccu cacccgcaca     1020

gaccgugguu gguacugcga caacgccggc uccguauccu ucuuuccaca agcugaaacc     1080

ugcaaaguuc aaucaaaccg agucuucugc gacaccauga acucccucac auugcccagc     1140

gaagucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa aaucaugacc     1200

uccaaaaccg acgucagcuc cagcgugauc acaagccuag gcgcgaucgu cagcugcuac     1260

ggcaaaacca aaugcacagc cuccaacaaa ugccgcggaa ucauaaaaac auucaguaac     1320

ggcugcgacu acguguccaa uaaaggaguc gacaccguau ccgucggaaa cacccucuac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau uaucaacuuc     1440

uacgaccccc uaguuuuccc cuccgacgag uucgacgcaa gcauuuccca agucaacgaa     1500

aagaucaauc aaucccucgc cuucauacgc aaaagcgacg aacuacuaca caacguaaac     1560

gccggcaaaa gcaccaccaa caucaugauc acaacaauca ucaucgucau caucgucauc     1620

cuacucucac ucaucgccgu uggccuacua cucuacugca aagcccgcuc cacacccguc     1680

acccucucaa aagaccaacu cuccggcauc aacaacaucg cauucagcaa cugaggacua     1740

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg     1800

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1860

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7829
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7829
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7830
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7830
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccgguccacc cccgugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7831
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7831
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7832
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7832
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcucaaca cccgugaccc ugaguaaaga ucaacucucu     1680

ggaaucaaua acauugcuuu cagcaauuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7833
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7833
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7834
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7834
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaagcaca cccgugaccc uuucuaaaga ucaacucucc     1680

ggcaucaaua acaucgcguu cagcaauuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7835
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7835
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaacgcaa ucacaacuau acuaacagca guaacauucu gcuuugccuc aggucaaaac      180

auaacagagg aauuuuacca auccacaugc ucugcuguaa gcaaaggaua ccucggagca      240

uuaagaacug gaugguacac cucaguaaua acuauagaac uaucaaacau aaaagaaaua      300

aaauguaaug gcacagacgc aaaagugaaa uuaaucaaac aagaacucga uaaauacaaa      360

aaugccguaa ccgaucucca acuuuuaaug caaagcacac ccgcaacagg uuccggguca      420

gcaauagcaa gcggaguugc aguaugcaaa guacuacacu uagaaggaga aguaaauaaa      480

aucaaaucag ccuuacuauc aacaaauaaa gcaguuguau cacucucagg augcggagua      540

uccguacuaa cauuuaaagu acuagaucua aaaaacuaca uagauaaaca acucuuacca      600

auacuaaaua aacaaucaug uuccauaccc aacauagaaa ccguuaucga auuucaacaa      660

aaaaacaaca gauuacuaga aaucacacga gaauuuucag uaaaugcugg agucacaaca      720

ccaguuagua cauacaugcu caccaauuca gaacuacuaa guuuaauuaa cgauaugcca      780

auaacaaacg accaaaaaaa acuaauguca aauaacguac aaauaguaag acaacaauca      840

uacucaauca ugugcauaau aaaagaagaa guacuagccu auguagucca auuaccacuc      900

uacggcguaa ucgacacccc augcuggaaa uuacacacaa gcccauuaug caccaccaac      960

acaaaagaag guucaaacau uugcuuaacc agaaccgauc gaggauggua cugcgauaac     1020

gcaggaucug ucuccuuuuu cccacaagcc gaaacaugca aaguucaauc aaaccgaguu     1080

uucugugaca cuaugaacuc acucacacuu ccaagcgaag uaaaccuaug caacguagau     1140

auauuuaacc cuaaauacga cugcaaaaua augacaagca aaacagacgu uaguucauca     1200

guaauuacaa gucuaggcgc aauaguguca ugcuacggaa aaacaaaaug caccgcaucc     1260

aauaaaugcc gaggaaucau uaaaacauuc ucaaacggau gcgacuacgu cagcaauaaa     1320

ggaguagaca cuguuucugu aggaaacacc cuauacuaug uaaacaaaca agaaggucaa     1380

ucacuauacg uaaagggaga accaauuaua aauuuuuacg accccuuagu auuuccaagu     1440

gaugaauuug acgcaucuau aagucaaguu aacgaaaaaa uuaaccaauc acuugcauuu     1500

auaagaaaau cagacgaacu acuccauaau guaaacgcag guaaaucaac aacaaacauc     1560

augaucacaa ccauaauaau aguaauaauu guaauauuac uaucacuaau agcaguagga     1620

uuacuacucu acugcaaagc uagaucuacc ccggucacac ucucaaaaga ccaauuaucu     1680

ggaauaaaca auauagcauu cagcaacuaa ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7836
<211>  1973
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7836
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gccaacgcca uaaccaccau ccucaccgcc gucaccuucu gcuucgcuuc uggccaaaac      180

auaaccgaag aguucuacca auccacgugc ucugccgugu caaaaggcua ccucggagcc      240

cuccgcacag ggugguacac uuccgucauc accaucgaac ucucuaacau caaagaaauc      300

aagugcaacg gcacagacgc gaaagucaag cucaucaaac aagaacuaga caaauacaaa      360

aacgccguaa cagaccucca acuccuaaug caguccacac cagccacagg cuccggcagc      420

gccaucgccu ccggcgucgc ugucugcaaa guccuacacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccuuag caccaacaaa gcagucgucu cuuuaagcgg gugcggaguc      540

ucuguccuaa ccuuuaaagu acucgaccuc aaaaacuaca ucgacaaaca acuacuacca      600

auacuaaaca aacagagcug cuccauuccc aacaucgaaa ccguuaucga guuccaacaa      660

aagaacaacc gccuccucga aaucacccgc gaguucuccg ucaacgcagg cgucaccacc      720

ccagucucca ccuauaugcu aaccaacagc gaacuccuca gccucaucaa ugacaugcca      780

aucaccaacg accaaaagaa acucaugucc aacaacguac agauaguccg ccagcagucc      840

uacagcauca ugugcaucau caaagaagaa gugcucgccu acgugguaca acucccucuc      900

uacggaguca uugauacacc cugcuggaaa cuccacacaa gcccccucug cacuacaaac      960

accaaagaag gcucuaacau augccucacc cgcacagacc gugguuggua cugcgacaac     1020

gccggcuccg uauccuucuu uccacaagcu gaaaccugca aaguucaauc aaaccgaguc     1080

uucugcgaca ccaugaacuc ccucacauug cccagcgaag ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaaaauc augaccucca aaaccgacgu cagcuccagc     1200

gugaucacaa gccuaggcgc gaucgucagc ugcuacggca aaaccaaaug cacagccucc     1260

aacaaaugcc gcggaaucau aaaaacauuc aguaacggcu gcgacuacgu guccaauaaa     1320

ggagucgaca ccguauccgu cggaaacacc cucuacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccauuauc aacuucuacg acccccuagu uuuccccucc     1440

gacgaguucg acgcaagcau uucccaaguc aacgaaaaga ucaaucaauc ccucgccuuc     1500

auacgcaaaa gcgacgaacu acuacacaac guaaacgccg gcaaaagcac caccaacauc     1560

augaucacaa caaucaucau cgucaucauc gucauccuac ucucacucau cgccguuggc     1620

cuacuacucu acugcaaagc ccgcuccaca cccgucaccc ucucaaaaga ccaacucucc     1680

ggcaucaaca acaucgcauu cagcaacuga ggacuaguaa uaaggaaacu guaugaaugu     1740

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1800

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1920

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1973


<210>  7837
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7837
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7838
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7838
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccgguccacc cccgugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7839
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7839
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7840
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7840
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcucaaca cccgugaccc ugaguaaaga ucaacucucu     1680

ggaaucaaua acauugcuuu cagcaauuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7841
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7841
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7842
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7842
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaagcaca cccgugaccc uuucuaaaga ucaacucucc     1680

ggcaucaaua acaucgcguu cagcaauuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7843
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7843
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaacgcaa ucacaacuau acuaacagca guaacauucu gcuuugccuc aggucaaaac      180

auaacagagg aauuuuacca auccacaugc ucugcuguaa gcaaaggaua ccucggagca      240

uuaagaacug gaugguacac cucaguaaua acuauagaac uaucaaacau aaaagaaaua      300

aaauguaaug gcacagacgc aaaagugaaa uuaaucaaac aagaacucga uaaauacaaa      360

aaugccguaa ccgaucucca acuuuuaaug caaagcacac ccgcaacagg uuccggguca      420

gcaauagcaa gcggaguugc aguaugcaaa guacuacacu uagaaggaga aguaaauaaa      480

aucaaaucag ccuuacuauc aacaaauaaa gcaguuguau cacucucagg augcggagua      540

uccguacuaa cauuuaaagu acuagaucua aaaaacuaca uagauaaaca acucuuacca      600

auacuaaaua aacaaucaug uuccauaccc aacauagaaa ccguuaucga auuucaacaa      660

aaaaacaaca gauuacuaga aaucacacga gaauuuucag uaaaugcugg agucacaaca      720

ccaguuagua cauacaugcu caccaauuca gaacuacuaa guuuaauuaa cgauaugcca      780

auaacaaacg accaaaaaaa acuaauguca aauaacguac aaauaguaag acaacaauca      840

uacucaauca ugugcauaau aaaagaagaa guacuagccu auguagucca auuaccacuc      900

uacggcguaa ucgacacccc augcuggaaa uuacacacaa gcccauuaug caccaccaac      960

acaaaagaag guucaaacau uugcuuaacc agaaccgauc gaggauggua cugcgauaac     1020

gcaggaucug ucuccuuuuu cccacaagcc gaaacaugca aaguucaauc aaaccgaguu     1080

uucugugaca cuaugaacuc acucacacuu ccaagcgaag uaaaccuaug caacguagau     1140

auauuuaacc cuaaauacga cugcaaaaua augacaagca aaacagacgu uaguucauca     1200

guaauuacaa gucuaggcgc aauaguguca ugcuacggaa aaacaaaaug caccgcaucc     1260

aauaaaugcc gaggaaucau uaaaacauuc ucaaacggau gcgacuacgu cagcaauaaa     1320

ggaguagaca cuguuucugu aggaaacacc cuauacuaug uaaacaaaca agaaggucaa     1380

ucacuauacg uaaagggaga accaauuaua aauuuuuacg accccuuagu auuuccaagu     1440

gaugaauuug acgcaucuau aagucaaguu aacgaaaaaa uuaaccaauc acuugcauuu     1500

auaagaaaau cagacgaacu acuccauaau guaaacgcag guaaaucaac aacaaacauc     1560

augaucacaa ccauaauaau aguaauaauu guaauauuac uaucacuaau agcaguagga     1620

uuacuacucu acugcaaagc uagaucuacc ccggucacac ucucaaaaga ccaauuaucu     1680

ggaauaaaca auauagcauu cagcaacuaa ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7844
<211>  1989
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7844
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gccaacgcca uaaccaccau ccucaccgcc gucaccuucu gcuucgcuuc uggccaaaac      180

auaaccgaag aguucuacca auccacgugc ucugccgugu caaaaggcua ccucggagcc      240

cuccgcacag ggugguacac uuccgucauc accaucgaac ucucuaacau caaagaaauc      300

aagugcaacg gcacagacgc gaaagucaag cucaucaaac aagaacuaga caaauacaaa      360

aacgccguaa cagaccucca acuccuaaug caguccacac cagccacagg cuccggcagc      420

gccaucgccu ccggcgucgc ugucugcaaa guccuacacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccuuag caccaacaaa gcagucgucu cuuuaagcgg gugcggaguc      540

ucuguccuaa ccuuuaaagu acucgaccuc aaaaacuaca ucgacaaaca acuacuacca      600

auacuaaaca aacagagcug cuccauuccc aacaucgaaa ccguuaucga guuccaacaa      660

aagaacaacc gccuccucga aaucacccgc gaguucuccg ucaacgcagg cgucaccacc      720

ccagucucca ccuauaugcu aaccaacagc gaacuccuca gccucaucaa ugacaugcca      780

aucaccaacg accaaaagaa acucaugucc aacaacguac agauaguccg ccagcagucc      840

uacagcauca ugugcaucau caaagaagaa gugcucgccu acgugguaca acucccucuc      900

uacggaguca uugauacacc cugcuggaaa cuccacacaa gcccccucug cacuacaaac      960

accaaagaag gcucuaacau augccucacc cgcacagacc gugguuggua cugcgacaac     1020

gccggcuccg uauccuucuu uccacaagcu gaaaccugca aaguucaauc aaaccgaguc     1080

uucugcgaca ccaugaacuc ccucacauug cccagcgaag ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaaaauc augaccucca aaaccgacgu cagcuccagc     1200

gugaucacaa gccuaggcgc gaucgucagc ugcuacggca aaaccaaaug cacagccucc     1260

aacaaaugcc gcggaaucau aaaaacauuc aguaacggcu gcgacuacgu guccaauaaa     1320

ggagucgaca ccguauccgu cggaaacacc cucuacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccauuauc aacuucuacg acccccuagu uuuccccucc     1440

gacgaguucg acgcaagcau uucccaaguc aacgaaaaga ucaaucaauc ccucgccuuc     1500

auacgcaaaa gcgacgaacu acuacacaac guaaacgccg gcaaaagcac caccaacauc     1560

augaucacaa caaucaucau cgucaucauc gucauccuac ucucacucau cgccguuggc     1620

cuacuacucu acugcaaagc ccgcuccaca cccgucaccc ucucaaaaga ccaacucucc     1680

ggcaucaaca acaucgcauu cagcaacuga ggacuaguac uggcugcauc ucccuuuccu     1740

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1800

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1860

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1980

accagaauu                                                             1989


<210>  7845
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7845
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7846
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7846
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccgguccacc cccgugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7847
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7847
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7848
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7848
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcucaaca cccgugaccc ugaguaaaga ucaacucucu     1680

ggaaucaaua acauugcuuu cagcaauuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7849
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7849
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7850
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7850
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaagcaca cccgugaccc uuucuaaaga ucaacucucc     1680

ggcaucaaua acaucgcguu cagcaauuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7851
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7851
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaacgcaa ucacaacuau acuaacagca guaacauucu gcuuugccuc aggucaaaac      180

auaacagagg aauuuuacca auccacaugc ucugcuguaa gcaaaggaua ccucggagca      240

uuaagaacug gaugguacac cucaguaaua acuauagaac uaucaaacau aaaagaaaua      300

aaauguaaug gcacagacgc aaaagugaaa uuaaucaaac aagaacucga uaaauacaaa      360

aaugccguaa ccgaucucca acuuuuaaug caaagcacac ccgcaacagg uuccggguca      420

gcaauagcaa gcggaguugc aguaugcaaa guacuacacu uagaaggaga aguaaauaaa      480

aucaaaucag ccuuacuauc aacaaauaaa gcaguuguau cacucucagg augcggagua      540

uccguacuaa cauuuaaagu acuagaucua aaaaacuaca uagauaaaca acucuuacca      600

auacuaaaua aacaaucaug uuccauaccc aacauagaaa ccguuaucga auuucaacaa      660

aaaaacaaca gauuacuaga aaucacacga gaauuuucag uaaaugcugg agucacaaca      720

ccaguuagua cauacaugcu caccaauuca gaacuacuaa guuuaauuaa cgauaugcca      780

auaacaaacg accaaaaaaa acuaauguca aauaacguac aaauaguaag acaacaauca      840

uacucaauca ugugcauaau aaaagaagaa guacuagccu auguagucca auuaccacuc      900

uacggcguaa ucgacacccc augcuggaaa uuacacacaa gcccauuaug caccaccaac      960

acaaaagaag guucaaacau uugcuuaacc agaaccgauc gaggauggua cugcgauaac     1020

gcaggaucug ucuccuuuuu cccacaagcc gaaacaugca aaguucaauc aaaccgaguu     1080

uucugugaca cuaugaacuc acucacacuu ccaagcgaag uaaaccuaug caacguagau     1140

auauuuaacc cuaaauacga cugcaaaaua augacaagca aaacagacgu uaguucauca     1200

guaauuacaa gucuaggcgc aauaguguca ugcuacggaa aaacaaaaug caccgcaucc     1260

aauaaaugcc gaggaaucau uaaaacauuc ucaaacggau gcgacuacgu cagcaauaaa     1320

ggaguagaca cuguuucugu aggaaacacc cuauacuaug uaaacaaaca agaaggucaa     1380

ucacuauacg uaaagggaga accaauuaua aauuuuuacg accccuuagu auuuccaagu     1440

gaugaauuug acgcaucuau aagucaaguu aacgaaaaaa uuaaccaauc acuugcauuu     1500

auaagaaaau cagacgaacu acuccauaau guaaacgcag guaaaucaac aacaaacauc     1560

augaucacaa ccauaauaau aguaauaauu guaauauuac uaucacuaau agcaguagga     1620

uuacuacucu acugcaaagc uagaucuacc ccggucacac ucucaaaaga ccaauuaucu     1680

ggaauaaaca auauagcauu cagcaacuaa ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7852
<211>  2205
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7852
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gccaacgcca uaaccaccau ccucaccgcc gucaccuucu gcuucgcuuc uggccaaaac      180

auaaccgaag aguucuacca auccacgugc ucugccgugu caaaaggcua ccucggagcc      240

cuccgcacag ggugguacac uuccgucauc accaucgaac ucucuaacau caaagaaauc      300

aagugcaacg gcacagacgc gaaagucaag cucaucaaac aagaacuaga caaauacaaa      360

aacgccguaa cagaccucca acuccuaaug caguccacac cagccacagg cuccggcagc      420

gccaucgccu ccggcgucgc ugucugcaaa guccuacacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccuuag caccaacaaa gcagucgucu cuuuaagcgg gugcggaguc      540

ucuguccuaa ccuuuaaagu acucgaccuc aaaaacuaca ucgacaaaca acuacuacca      600

auacuaaaca aacagagcug cuccauuccc aacaucgaaa ccguuaucga guuccaacaa      660

aagaacaacc gccuccucga aaucacccgc gaguucuccg ucaacgcagg cgucaccacc      720

ccagucucca ccuauaugcu aaccaacagc gaacuccuca gccucaucaa ugacaugcca      780

aucaccaacg accaaaagaa acucaugucc aacaacguac agauaguccg ccagcagucc      840

uacagcauca ugugcaucau caaagaagaa gugcucgccu acgugguaca acucccucuc      900

uacggaguca uugauacacc cugcuggaaa cuccacacaa gcccccucug cacuacaaac      960

accaaagaag gcucuaacau augccucacc cgcacagacc gugguuggua cugcgacaac     1020

gccggcuccg uauccuucuu uccacaagcu gaaaccugca aaguucaauc aaaccgaguc     1080

uucugcgaca ccaugaacuc ccucacauug cccagcgaag ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaaaauc augaccucca aaaccgacgu cagcuccagc     1200

gugaucacaa gccuaggcgc gaucgucagc ugcuacggca aaaccaaaug cacagccucc     1260

aacaaaugcc gcggaaucau aaaaacauuc aguaacggcu gcgacuacgu guccaauaaa     1320

ggagucgaca ccguauccgu cggaaacacc cucuacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccauuauc aacuucuacg acccccuagu uuuccccucc     1440

gacgaguucg acgcaagcau uucccaaguc aacgaaaaga ucaaucaauc ccucgccuuc     1500

auacgcaaaa gcgacgaacu acuacacaac guaaacgccg gcaaaagcac caccaacauc     1560

augaucacaa caaucaucau cgucaucauc gucauccuac ucucacucau cgccguuggc     1620

cuacuacucu acugcaaagc ccgcuccaca cccgucaccc ucucaaaaga ccaacucucc     1680

ggcaucaaca acaucgcauu cagcaacuga ggacuaguga agggaacacc caaauuuaau     1740

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1800

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1860

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1920

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1980

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     2040

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     2160

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     2205


<210>  7853
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7853
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggagcacg cccgucaccc uguccaagga ccagcugagc     1680

ggcaucaaca acaucgcguu cuccaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7854
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7854
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccgguccacc cccgugaccc ugagcaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7855
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7855
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcuccacc cccgucaccc ucuccaagga ccagcucucc     1680

ggcaucaaca acaucgccuu cuccaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7856
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7856
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcucaaca cccgugaccc ugaguaaaga ucaacucucu     1680

ggaaucaaua acauugcuuu cagcaauuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7857
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7857
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaagcacc cccgugaccc ugagcaagga ccagcugagc     1680

ggcaucaaca acaucgccuu cagcaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7858
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7858
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaagcaca cccgugaccc uuucuaaaga ucaacucucc     1680

ggcaucaaua acaucgcguu cagcaauuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7859
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7859
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuauu aauauuaaaa      120

gcaaacgcaa ucacaacuau acuaacagca guaacauucu gcuuugccuc aggucaaaac      180

auaacagagg aauuuuacca auccacaugc ucugcuguaa gcaaaggaua ccucggagca      240

uuaagaacug gaugguacac cucaguaaua acuauagaac uaucaaacau aaaagaaaua      300

aaauguaaug gcacagacgc aaaagugaaa uuaaucaaac aagaacucga uaaauacaaa      360

aaugccguaa ccgaucucca acuuuuaaug caaagcacac ccgcaacagg uuccggguca      420

gcaauagcaa gcggaguugc aguaugcaaa guacuacacu uagaaggaga aguaaauaaa      480

aucaaaucag ccuuacuauc aacaaauaaa gcaguuguau cacucucagg augcggagua      540

uccguacuaa cauuuaaagu acuagaucua aaaaacuaca uagauaaaca acucuuacca      600

auacuaaaua aacaaucaug uuccauaccc aacauagaaa ccguuaucga auuucaacaa      660

aaaaacaaca gauuacuaga aaucacacga gaauuuucag uaaaugcugg agucacaaca      720

ccaguuagua cauacaugcu caccaauuca gaacuacuaa guuuaauuaa cgauaugcca      780

auaacaaacg accaaaaaaa acuaauguca aauaacguac aaauaguaag acaacaauca      840

uacucaauca ugugcauaau aaaagaagaa guacuagccu auguagucca auuaccacuc      900

uacggcguaa ucgacacccc augcuggaaa uuacacacaa gcccauuaug caccaccaac      960

acaaaagaag guucaaacau uugcuuaacc agaaccgauc gaggauggua cugcgauaac     1020

gcaggaucug ucuccuuuuu cccacaagcc gaaacaugca aaguucaauc aaaccgaguu     1080

uucugugaca cuaugaacuc acucacacuu ccaagcgaag uaaaccuaug caacguagau     1140

auauuuaacc cuaaauacga cugcaaaaua augacaagca aaacagacgu uaguucauca     1200

guaauuacaa gucuaggcgc aauaguguca ugcuacggaa aaacaaaaug caccgcaucc     1260

aauaaaugcc gaggaaucau uaaaacauuc ucaaacggau gcgacuacgu cagcaauaaa     1320

ggaguagaca cuguuucugu aggaaacacc cuauacuaug uaaacaaaca agaaggucaa     1380

ucacuauacg uaaagggaga accaauuaua aauuuuuacg accccuuagu auuuccaagu     1440

gaugaauuug acgcaucuau aagucaaguu aacgaaaaaa uuaaccaauc acuugcauuu     1500

auaagaaaau cagacgaacu acuccauaau guaaacgcag guaaaucaac aacaaacauc     1560

augaucacaa ccauaauaau aguaauaauu guaauauuac uaucacuaau agcaguagga     1620

uuacuacucu acugcaaagc uagaucuacc ccggucacac ucucaaaaga ccaauuaucu     1680

ggaauaaaca auauagcauu cagcaacuaa ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7860
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7860
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccuuaaa      120

gccaacgcca uaaccaccau ccucaccgcc gucaccuucu gcuucgcuuc uggccaaaac      180

auaaccgaag aguucuacca auccacgugc ucugccgugu caaaaggcua ccucggagcc      240

cuccgcacag ggugguacac uuccgucauc accaucgaac ucucuaacau caaagaaauc      300

aagugcaacg gcacagacgc gaaagucaag cucaucaaac aagaacuaga caaauacaaa      360

aacgccguaa cagaccucca acuccuaaug caguccacac cagccacagg cuccggcagc      420

gccaucgccu ccggcgucgc ugucugcaaa guccuacacc ucgaaggcga agucaacaaa      480

aucaagucag cccuccuuag caccaacaaa gcagucgucu cuuuaagcgg gugcggaguc      540

ucuguccuaa ccuuuaaagu acucgaccuc aaaaacuaca ucgacaaaca acuacuacca      600

auacuaaaca aacagagcug cuccauuccc aacaucgaaa ccguuaucga guuccaacaa      660

aagaacaacc gccuccucga aaucacccgc gaguucuccg ucaacgcagg cgucaccacc      720

ccagucucca ccuauaugcu aaccaacagc gaacuccuca gccucaucaa ugacaugcca      780

aucaccaacg accaaaagaa acucaugucc aacaacguac agauaguccg ccagcagucc      840

uacagcauca ugugcaucau caaagaagaa gugcucgccu acgugguaca acucccucuc      900

uacggaguca uugauacacc cugcuggaaa cuccacacaa gcccccucug cacuacaaac      960

accaaagaag gcucuaacau augccucacc cgcacagacc gugguuggua cugcgacaac     1020

gccggcuccg uauccuucuu uccacaagcu gaaaccugca aaguucaauc aaaccgaguc     1080

uucugcgaca ccaugaacuc ccucacauug cccagcgaag ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaaaauc augaccucca aaaccgacgu cagcuccagc     1200

gugaucacaa gccuaggcgc gaucgucagc ugcuacggca aaaccaaaug cacagccucc     1260

aacaaaugcc gcggaaucau aaaaacauuc aguaacggcu gcgacuacgu guccaauaaa     1320

ggagucgaca ccguauccgu cggaaacacc cucuacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccauuauc aacuucuacg acccccuagu uuuccccucc     1440

gacgaguucg acgcaagcau uucccaaguc aacgaaaaga ucaaucaauc ccucgccuuc     1500

auacgcaaaa gcgacgaacu acuacacaac guaaacgccg gcaaaagcac caccaacauc     1560

augaucacaa caaucaucau cgucaucauc gucauccuac ucucacucau cgccguuggc     1620

cuacuacucu acugcaaagc ccgcuccaca cccgucaccc ucucaaaaga ccaacucucc     1680

ggcaucaaca acaucgcauu cagcaacuga ggacuagugg aagcauuuuc cuggcugauu     1740

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1800

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  7861
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7861
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7862
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7862
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7863
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7863
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7864
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7864
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu caacacccgu gacccugagu     1740

aaagaucaac ucucuggaau caauaacauu gcuuucagca auugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7865
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7865
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7866
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7866
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagaa gcacacccgu gacccuuucu     1740

aaagaucaac ucuccggcau caauaacauc gcguucagca auugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7867
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7867
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa cgcaaucaca acuauacuaa cagcaguaac auucugcuuu      240

gccucagguc aaaacauaac agaggaauuu uaccaaucca caugcucugc uguaagcaaa      300

ggauaccucg gagcauuaag aacuggaugg uacaccucag uaauaacuau agaacuauca      360

aacauaaaag aaauaaaaug uaauggcaca gacgcaaaag ugaaauuaau caaacaagaa      420

cucgauaaau acaaaaaugc cguaaccgau cuccaacuuu uaaugcaaag cacacccgca      480

acagguuccg ggucagcaau agcaagcgga guugcaguau gcaaaguacu acacuuagaa      540

ggagaaguaa auaaaaucaa aucagccuua cuaucaacaa auaaagcagu uguaucacuc      600

ucaggaugcg gaguauccgu acuaacauuu aaaguacuag aucuaaaaaa cuacauagau      660

aaacaacucu uaccaauacu aaauaaacaa ucauguucca uacccaacau agaaaccguu      720

aucgaauuuc aacaaaaaaa caacagauua cuagaaauca cacgagaauu uucaguaaau      780

gcuggaguca caacaccagu uaguacauac augcucacca auucagaacu acuaaguuua      840

auuaacgaua ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguacaaaua      900

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguacu agccuaugua      960

guccaauuac cacucuacgg cguaaucgac accccaugcu ggaaauuaca cacaagccca     1020

uuaugcacca ccaacacaaa agaagguuca aacauuugcu uaaccagaac cgaucgagga     1080

ugguacugcg auaacgcagg aucugucucc uuuuucccac aagccgaaac augcaaaguu     1140

caaucaaacc gaguuuucug ugacacuaug aacucacuca cacuuccaag cgaaguaaac     1200

cuaugcaacg uagauauauu uaacccuaaa uacgacugca aaauaaugac aagcaaaaca     1260

gacguuaguu caucaguaau uacaagucua ggcgcaauag ugucaugcua cggaaaaaca     1320

aaaugcaccg cauccaauaa augccgagga aucauuaaaa cauucucaaa cggaugcgac     1380

uacgucagca auaaaggagu agacacuguu ucuguaggaa acacccuaua cuauguaaac     1440

aaacaagaag gucaaucacu auacguaaag ggagaaccaa uuauaaauuu uuacgacccc     1500

uuaguauuuc caagugauga auuugacgca ucuauaaguc aaguuaacga aaaaauuaac     1560

caaucacuug cauuuauaag aaaaucagac gaacuacucc auaauguaaa cgcagguaaa     1620

ucaacaacaa acaucaugau cacaaccaua auaauaguaa uaauuguaau auuacuauca     1680

cuaauagcag uaggauuacu acucuacugc aaagcuagau cuaccccggu cacacucuca     1740

aaagaccaau uaucuggaau aaacaauaua gcauucagca acuaaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7868
<211>  2048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7868
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagccaa cgccauaacc accauccuca ccgccgucac cuucugcuuc      240

gcuucuggcc aaaacauaac cgaagaguuc uaccaaucca cgugcucugc cgugucaaaa      300

ggcuaccucg gagcccuccg cacagggugg uacacuuccg ucaucaccau cgaacucucu      360

aacaucaaag aaaucaagug caacggcaca gacgcgaaag ucaagcucau caaacaagaa      420

cuagacaaau acaaaaacgc cguaacagac cuccaacucc uaaugcaguc cacaccagcc      480

acaggcuccg gcagcgccau cgccuccggc gucgcugucu gcaaaguccu acaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cuuagcacca acaaagcagu cgucucuuua      600

agcgggugcg gagucucugu ccuaaccuuu aaaguacucg accucaaaaa cuacaucgac      660

aaacaacuac uaccaauacu aaacaaacag agcugcucca uucccaacau cgaaaccguu      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cccgcgaguu cuccgucaac      780

gcaggcguca ccaccccagu cuccaccuau augcuaacca acagcgaacu ccucagccuc      840

aucaaugaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacagaua      900

guccgccagc aguccuacag caucaugugc aucaucaaag aagaagugcu cgccuacgug      960

guacaacucc cucucuacgg agucauugau acacccugcu ggaaacucca cacaagcccc     1020

cucugcacua caaacaccaa agaaggcucu aacauaugcc ucacccgcac agaccguggu     1080

ugguacugcg acaacgccgg cuccguaucc uucuuuccac aagcugaaac cugcaaaguu     1140

caaucaaacc gagucuucug cgacaccaug aacucccuca cauugcccag cgaagucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca aaaucaugac cuccaaaacc     1260

gacgucagcu ccagcgugau cacaagccua ggcgcgaucg ucagcugcua cggcaaaacc     1320

aaaugcacag ccuccaacaa augccgcgga aucauaaaaa cauucaguaa cggcugcgac     1380

uacgugucca auaaaggagu cgacaccgua uccgucggaa acacccucua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca uuaucaacuu cuacgacccc     1500

cuaguuuucc ccuccgacga guucgacgca agcauuuccc aagucaacga aaagaucaau     1560

caaucccucg ccuucauacg caaaagcgac gaacuacuac acaacguaaa cgccggcaaa     1620

agcaccacca acaucaugau cacaacaauc aucaucguca ucaucgucau ccuacucuca     1680

cucaucgccg uuggccuacu acucuacugc aaagcccgcu ccacacccgu cacccucuca     1740

aaagaccaac ucuccggcau caacaacauc gcauucagca acugaggacu aguaauaagg     1800

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1860

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1920

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     2040

ccagaauu                                                              2048


<210>  7869
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7869
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7870
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7870
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7871
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7871
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7872
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7872
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu caacacccgu gacccugagu     1740

aaagaucaac ucucuggaau caauaacauu gcuuucagca auugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7873
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7873
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7874
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7874
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagaa gcacacccgu gacccuuucu     1740

aaagaucaac ucuccggcau caauaacauc gcguucagca auugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7875
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7875
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa cgcaaucaca acuauacuaa cagcaguaac auucugcuuu      240

gccucagguc aaaacauaac agaggaauuu uaccaaucca caugcucugc uguaagcaaa      300

ggauaccucg gagcauuaag aacuggaugg uacaccucag uaauaacuau agaacuauca      360

aacauaaaag aaauaaaaug uaauggcaca gacgcaaaag ugaaauuaau caaacaagaa      420

cucgauaaau acaaaaaugc cguaaccgau cuccaacuuu uaaugcaaag cacacccgca      480

acagguuccg ggucagcaau agcaagcgga guugcaguau gcaaaguacu acacuuagaa      540

ggagaaguaa auaaaaucaa aucagccuua cuaucaacaa auaaagcagu uguaucacuc      600

ucaggaugcg gaguauccgu acuaacauuu aaaguacuag aucuaaaaaa cuacauagau      660

aaacaacucu uaccaauacu aaauaaacaa ucauguucca uacccaacau agaaaccguu      720

aucgaauuuc aacaaaaaaa caacagauua cuagaaauca cacgagaauu uucaguaaau      780

gcuggaguca caacaccagu uaguacauac augcucacca auucagaacu acuaaguuua      840

auuaacgaua ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguacaaaua      900

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguacu agccuaugua      960

guccaauuac cacucuacgg cguaaucgac accccaugcu ggaaauuaca cacaagccca     1020

uuaugcacca ccaacacaaa agaagguuca aacauuugcu uaaccagaac cgaucgagga     1080

ugguacugcg auaacgcagg aucugucucc uuuuucccac aagccgaaac augcaaaguu     1140

caaucaaacc gaguuuucug ugacacuaug aacucacuca cacuuccaag cgaaguaaac     1200

cuaugcaacg uagauauauu uaacccuaaa uacgacugca aaauaaugac aagcaaaaca     1260

gacguuaguu caucaguaau uacaagucua ggcgcaauag ugucaugcua cggaaaaaca     1320

aaaugcaccg cauccaauaa augccgagga aucauuaaaa cauucucaaa cggaugcgac     1380

uacgucagca auaaaggagu agacacuguu ucuguaggaa acacccuaua cuauguaaac     1440

aaacaagaag gucaaucacu auacguaaag ggagaaccaa uuauaaauuu uuacgacccc     1500

uuaguauuuc caagugauga auuugacgca ucuauaaguc aaguuaacga aaaaauuaac     1560

caaucacuug cauuuauaag aaaaucagac gaacuacucc auaauguaaa cgcagguaaa     1620

ucaacaacaa acaucaugau cacaaccaua auaauaguaa uaauuguaau auuacuauca     1680

cuaauagcag uaggauuacu acucuacugc aaagcuagau cuaccccggu cacacucuca     1740

aaagaccaau uaucuggaau aaacaauaua gcauucagca acuaaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7876
<211>  2064
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7876
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagccaa cgccauaacc accauccuca ccgccgucac cuucugcuuc      240

gcuucuggcc aaaacauaac cgaagaguuc uaccaaucca cgugcucugc cgugucaaaa      300

ggcuaccucg gagcccuccg cacagggugg uacacuuccg ucaucaccau cgaacucucu      360

aacaucaaag aaaucaagug caacggcaca gacgcgaaag ucaagcucau caaacaagaa      420

cuagacaaau acaaaaacgc cguaacagac cuccaacucc uaaugcaguc cacaccagcc      480

acaggcuccg gcagcgccau cgccuccggc gucgcugucu gcaaaguccu acaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cuuagcacca acaaagcagu cgucucuuua      600

agcgggugcg gagucucugu ccuaaccuuu aaaguacucg accucaaaaa cuacaucgac      660

aaacaacuac uaccaauacu aaacaaacag agcugcucca uucccaacau cgaaaccguu      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cccgcgaguu cuccgucaac      780

gcaggcguca ccaccccagu cuccaccuau augcuaacca acagcgaacu ccucagccuc      840

aucaaugaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacagaua      900

guccgccagc aguccuacag caucaugugc aucaucaaag aagaagugcu cgccuacgug      960

guacaacucc cucucuacgg agucauugau acacccugcu ggaaacucca cacaagcccc     1020

cucugcacua caaacaccaa agaaggcucu aacauaugcc ucacccgcac agaccguggu     1080

ugguacugcg acaacgccgg cuccguaucc uucuuuccac aagcugaaac cugcaaaguu     1140

caaucaaacc gagucuucug cgacaccaug aacucccuca cauugcccag cgaagucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca aaaucaugac cuccaaaacc     1260

gacgucagcu ccagcgugau cacaagccua ggcgcgaucg ucagcugcua cggcaaaacc     1320

aaaugcacag ccuccaacaa augccgcgga aucauaaaaa cauucaguaa cggcugcgac     1380

uacgugucca auaaaggagu cgacaccgua uccgucggaa acacccucua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca uuaucaacuu cuacgacccc     1500

cuaguuuucc ccuccgacga guucgacgca agcauuuccc aagucaacga aaagaucaau     1560

caaucccucg ccuucauacg caaaagcgac gaacuacuac acaacguaaa cgccggcaaa     1620

agcaccacca acaucaugau cacaacaauc aucaucguca ucaucgucau ccuacucuca     1680

cucaucgccg uuggccuacu acucuacugc aaagcccgcu ccacacccgu cacccucuca     1740

aaagaccaac ucuccggcau caacaacauc gcauucagca acugaggacu aguacuggcu     1800

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1860

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1920

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2040

gcucuuuuca gagccaccag aauu                                            2064


<210>  7877
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7877
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccgga gcacgcccgu cacccugucc     1740

aaggaccagc ugagcggcau caacaacauc gcguucucca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7878
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7878
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu ccacccccgu gacccugagc     1740

aaggaccagc ucuccggcau caacaacauc gccuucagca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7879
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7879
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu ccacccccgu cacccucucc     1740

aaggaccagc ucuccggcau caacaacauc gccuucucca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7880
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7880
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu caacacccgu gacccugagu     1740

aaagaucaac ucucuggaau caauaacauu gcuuucagca auugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7881
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7881
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagaa gcacccccgu gacccugagc     1740

aaggaccagc ugagcggcau caacaacauc gccuucagca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7882
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7882
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagaa gcacacccgu gacccuuucu     1740

aaagaucaac ucuccggcau caauaacauc gcguucagca auugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7883
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7883
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuauuaauau uaaaagcaaa cgcaaucaca acuauacuaa cagcaguaac auucugcuuu      240

gccucagguc aaaacauaac agaggaauuu uaccaaucca caugcucugc uguaagcaaa      300

ggauaccucg gagcauuaag aacuggaugg uacaccucag uaauaacuau agaacuauca      360

aacauaaaag aaauaaaaug uaauggcaca gacgcaaaag ugaaauuaau caaacaagaa      420

cucgauaaau acaaaaaugc cguaaccgau cuccaacuuu uaaugcaaag cacacccgca      480

acagguuccg ggucagcaau agcaagcgga guugcaguau gcaaaguacu acacuuagaa      540

ggagaaguaa auaaaaucaa aucagccuua cuaucaacaa auaaagcagu uguaucacuc      600

ucaggaugcg gaguauccgu acuaacauuu aaaguacuag aucuaaaaaa cuacauagau      660

aaacaacucu uaccaauacu aaauaaacaa ucauguucca uacccaacau agaaaccguu      720

aucgaauuuc aacaaaaaaa caacagauua cuagaaauca cacgagaauu uucaguaaau      780

gcuggaguca caacaccagu uaguacauac augcucacca auucagaacu acuaaguuua      840

auuaacgaua ugccaauaac aaacgaccaa aaaaaacuaa ugucaaauaa cguacaaaua      900

guaagacaac aaucauacuc aaucaugugc auaauaaaag aagaaguacu agccuaugua      960

guccaauuac cacucuacgg cguaaucgac accccaugcu ggaaauuaca cacaagccca     1020

uuaugcacca ccaacacaaa agaagguuca aacauuugcu uaaccagaac cgaucgagga     1080

ugguacugcg auaacgcagg aucugucucc uuuuucccac aagccgaaac augcaaaguu     1140

caaucaaacc gaguuuucug ugacacuaug aacucacuca cacuuccaag cgaaguaaac     1200

cuaugcaacg uagauauauu uaacccuaaa uacgacugca aaauaaugac aagcaaaaca     1260

gacguuaguu caucaguaau uacaagucua ggcgcaauag ugucaugcua cggaaaaaca     1320

aaaugcaccg cauccaauaa augccgagga aucauuaaaa cauucucaaa cggaugcgac     1380

uacgucagca auaaaggagu agacacuguu ucuguaggaa acacccuaua cuauguaaac     1440

aaacaagaag gucaaucacu auacguaaag ggagaaccaa uuauaaauuu uuacgacccc     1500

uuaguauuuc caagugauga auuugacgca ucuauaaguc aaguuaacga aaaaauuaac     1560

caaucacuug cauuuauaag aaaaucagac gaacuacucc auaauguaaa cgcagguaaa     1620

ucaacaacaa acaucaugau cacaaccaua auaauaguaa uaauuguaau auuacuauca     1680

cuaauagcag uaggauuacu acucuacugc aaagcuagau cuaccccggu cacacucuca     1740

aaagaccaau uaucuggaau aaacaauaua gcauucagca acuaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7884
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7884
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc uuaaagccaa cgccauaacc accauccuca ccgccgucac cuucugcuuc      240

gcuucuggcc aaaacauaac cgaagaguuc uaccaaucca cgugcucugc cgugucaaaa      300

ggcuaccucg gagcccuccg cacagggugg uacacuuccg ucaucaccau cgaacucucu      360

aacaucaaag aaaucaagug caacggcaca gacgcgaaag ucaagcucau caaacaagaa      420

cuagacaaau acaaaaacgc cguaacagac cuccaacucc uaaugcaguc cacaccagcc      480

acaggcuccg gcagcgccau cgccuccggc gucgcugucu gcaaaguccu acaccucgaa      540

ggcgaaguca acaaaaucaa gucagcccuc cuuagcacca acaaagcagu cgucucuuua      600

agcgggugcg gagucucugu ccuaaccuuu aaaguacucg accucaaaaa cuacaucgac      660

aaacaacuac uaccaauacu aaacaaacag agcugcucca uucccaacau cgaaaccguu      720

aucgaguucc aacaaaagaa caaccgccuc cucgaaauca cccgcgaguu cuccgucaac      780

gcaggcguca ccaccccagu cuccaccuau augcuaacca acagcgaacu ccucagccuc      840

aucaaugaca ugccaaucac caacgaccaa aagaaacuca uguccaacaa cguacagaua      900

guccgccagc aguccuacag caucaugugc aucaucaaag aagaagugcu cgccuacgug      960

guacaacucc cucucuacgg agucauugau acacccugcu ggaaacucca cacaagcccc     1020

cucugcacua caaacaccaa agaaggcucu aacauaugcc ucacccgcac agaccguggu     1080

ugguacugcg acaacgccgg cuccguaucc uucuuuccac aagcugaaac cugcaaaguu     1140

caaucaaacc gagucuucug cgacaccaug aacucccuca cauugcccag cgaagucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca aaaucaugac cuccaaaacc     1260

gacgucagcu ccagcgugau cacaagccua ggcgcgaucg ucagcugcua cggcaaaacc     1320

aaaugcacag ccuccaacaa augccgcgga aucauaaaaa cauucaguaa cggcugcgac     1380

uacgugucca auaaaggagu cgacaccgua uccgucggaa acacccucua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca uuaucaacuu cuacgacccc     1500

cuaguuuucc ccuccgacga guucgacgca agcauuuccc aagucaacga aaagaucaau     1560

caaucccucg ccuucauacg caaaagcgac gaacuacuac acaacguaaa cgccggcaaa     1620

agcaccacca acaucaugau cacaacaauc aucaucguca ucaucgucau ccuacucuca     1680

cucaucgccg uuggccuacu acucuacugc aaagcccgcu ccacacccgu cacccucuca     1740

aaagaccaac ucuccggcau caacaacauc gcauucagca acugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7885
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7885
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggagcacgcc cgucacccug     1620

uccaaggacc agcugagcgg caucaacaac aucgcguucu ccaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7886
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7886
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      480

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1200

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1320

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccgugggccu ccugcuguac ugcaaggccc gguccacccc cgugacccug     1620

agcaaggacc agcucuccgg caucaacaac aucgccuuca gcaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7887
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7887
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcuccacccc cgucacccuc     1620

uccaaggacc agcucuccgg caucaacaac aucgccuucu ccaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7888
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7888
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      480

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      540

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      600

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      660

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      720

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      780

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau      840

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      900

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu      960

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1020

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1080

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1140

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1200

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1260

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1320

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1380

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1440

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1500

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1560

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcucaacacc cgugacccug     1620

aguaaagauc aacucucugg aaucaauaac auugcuuuca gcaauugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7889
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7889
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaagcacccc cgugacccug     1620

agcaaggacc agcugagcgg caucaacaac aucgccuuca gcaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7890
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7890
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      480

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      540

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      600

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      660

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      720

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      780

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau      840

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc      900

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc      960

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1020

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1080

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1140

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1200

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1260

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1320

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1380

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1440

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1500

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1560

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaagcacacc cgugacccuu     1620

ucuaaagauc aacucuccgg caucaauaac aucgcguuca gcaauugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7891
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7891
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuauuaa uauuaaaagc aaacgcaauc acaacuauac uaacagcagu aacauucugc      120

uuugccucag gucaaaacau aacagaggaa uuuuaccaau ccacaugcuc ugcuguaagc      180

aaaggauacc ucggagcauu aagaacugga ugguacaccu caguaauaac uauagaacua      240

ucaaacauaa aagaaauaaa auguaauggc acagacgcaa aagugaaauu aaucaaacaa      300

gaacucgaua aauacaaaaa ugccguaacc gaucuccaac uuuuaaugca aagcacaccc      360

gcaacagguu ccgggucagc aauagcaagc ggaguugcag uaugcaaagu acuacacuua      420

gaaggagaag uaaauaaaau caaaucagcc uuacuaucaa caaauaaagc aguuguauca      480

cucucaggau gcggaguauc cguacuaaca uuuaaaguac uagaucuaaa aaacuacaua      540

gauaaacaac ucuuaccaau acuaaauaaa caaucauguu ccauacccaa cauagaaacc      600

guuaucgaau uucaacaaaa aaacaacaga uuacuagaaa ucacacgaga auuuucagua      660

aaugcuggag ucacaacacc aguuaguaca uacaugcuca ccaauucaga acuacuaagu      720

uuaauuaacg auaugccaau aacaaacgac caaaaaaaac uaaugucaaa uaacguacaa      780

auaguaagac aacaaucaua cucaaucaug ugcauaauaa aagaagaagu acuagccuau      840

guaguccaau uaccacucua cggcguaauc gacaccccau gcuggaaauu acacacaagc      900

ccauuaugca ccaccaacac aaaagaaggu ucaaacauuu gcuuaaccag aaccgaucga      960

ggaugguacu gcgauaacgc aggaucuguc uccuuuuucc cacaagccga aacaugcaaa     1020

guucaaucaa accgaguuuu cugugacacu augaacucac ucacacuucc aagcgaagua     1080

aaccuaugca acguagauau auuuaacccu aaauacgacu gcaaaauaau gacaagcaaa     1140

acagacguua guucaucagu aauuacaagu cuaggcgcaa uagugucaug cuacggaaaa     1200

acaaaaugca ccgcauccaa uaaaugccga ggaaucauua aaacauucuc aaacggaugc     1260

gacuacguca gcaauaaagg aguagacacu guuucuguag gaaacacccu auacuaugua     1320

aacaaacaag aaggucaauc acuauacgua aagggagaac caauuauaaa uuuuuacgac     1380

cccuuaguau uuccaaguga ugaauuugac gcaucuauaa gucaaguuaa cgaaaaaauu     1440

aaccaaucac uugcauuuau aagaaaauca gacgaacuac uccauaaugu aaacgcaggu     1500

aaaucaacaa caaacaucau gaucacaacc auaauaauag uaauaauugu aauauuacua     1560

ucacuaauag caguaggauu acuacucuac ugcaaagcua gaucuacccc ggucacacuc     1620

ucaaaagacc aauuaucugg aauaaacaau auagcauuca gcaacuaagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7892
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7892
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccuuaaagc caacgccaua accaccaucc ucaccgccgu caccuucugc      120

uucgcuucug gccaaaacau aaccgaagag uucuaccaau ccacgugcuc ugccguguca      180

aaaggcuacc ucggagcccu ccgcacaggg ugguacacuu ccgucaucac caucgaacuc      240

ucuaacauca aagaaaucaa gugcaacggc acagacgcga aagucaagcu caucaaacaa      300

gaacuagaca aauacaaaaa cgccguaaca gaccuccaac uccuaaugca guccacacca      360

gccacaggcu ccggcagcgc caucgccucc ggcgucgcug ucugcaaagu ccuacaccuc      420

gaaggcgaag ucaacaaaau caagucagcc cuccuuagca ccaacaaagc agucgucucu      480

uuaagcgggu gcggagucuc uguccuaacc uuuaaaguac ucgaccucaa aaacuacauc      540

gacaaacaac uacuaccaau acuaaacaaa cagagcugcu ccauucccaa caucgaaacc      600

guuaucgagu uccaacaaaa gaacaaccgc cuccucgaaa ucacccgcga guucuccguc      660

aacgcaggcg ucaccacccc agucuccacc uauaugcuaa ccaacagcga acuccucagc      720

cucaucaaug acaugccaau caccaacgac caaaagaaac ucauguccaa caacguacag      780

auaguccgcc agcaguccua cagcaucaug ugcaucauca aagaagaagu gcucgccuac      840

gugguacaac ucccucucua cggagucauu gauacacccu gcuggaaacu ccacacaagc      900

ccccucugca cuacaaacac caaagaaggc ucuaacauau gccucacccg cacagaccgu      960

gguugguacu gcgacaacgc cggcuccgua uccuucuuuc cacaagcuga aaccugcaaa     1020

guucaaucaa accgagucuu cugcgacacc augaacuccc ucacauugcc cagcgaaguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaaaaucau gaccuccaaa     1140

accgacguca gcuccagcgu gaucacaagc cuaggcgcga ucgucagcug cuacggcaaa     1200

accaaaugca cagccuccaa caaaugccgc ggaaucauaa aaacauucag uaacggcugc     1260

gacuacgugu ccaauaaagg agucgacacc guauccgucg gaaacacccu cuacuacguc     1320

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccauuaucaa cuucuacgac     1380

ccccuaguuu uccccuccga cgaguucgac gcaagcauuu cccaagucaa cgaaaagauc     1440

aaucaauccc ucgccuucau acgcaaaagc gacgaacuac uacacaacgu aaacgccggc     1500

aaaagcacca ccaacaucau gaucacaaca aucaucaucg ucaucaucgu cauccuacuc     1560

ucacucaucg ccguuggccu acuacucuac ugcaaagccc gcuccacacc cgucacccuc     1620

ucaaaagacc aacucuccgg caucaacaac aucgcauuca gcaacugagg acuagugcau     1680

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag     1740

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua     1800

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1860

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7893
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7893
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc gagacgguga      600

ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc agcgugaacg      660

ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc cugucccuga      720

ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gcguacgugg      840

uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac acgagccccc      900

ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc gaccggggcu      960

gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc ugcaaggugc     1020

agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc gagguaaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac ggcaagacga     1200

agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac uacgugaaca     1320

agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc uacgacccgc     1380

uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag aagaucaacc     1440

agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac gccggcaaga     1500

gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc cugcuguccc     1560

ucaucgccgu ggggcugcug cucuacugca aggcccggag cacgcccguc acccugucca     1620

aggaccagcu gagcggcauc aacaacaucg cguucuccaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7894
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7894
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug gucagccucu      480

ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac uacaucgaca      540

agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc gagaccguga      600

ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc uccgugaacg      660

ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug cugagccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac accagccccc      900

ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc gaccggggcu      960

gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc gaggucaacc     1080

ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc agcaagaccg     1140

acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac gggaagacca     1200

agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac uacgucaaca     1320

agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc uacgaccccc     1380

ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag aagaucaacc     1440

agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac gccgggaagu     1500

ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc cuccugagcc     1560

ugaucgccgu gggccuccug cuguacugca aggcccgguc cacccccgug acccugagca     1620

aggaccagcu cuccggcauc aacaacaucg ccuucagcaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7895
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7895
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac uacaucgaca      540

agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc gagaccguca      600

ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg      660

ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc cucucccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac guccagaucg      780

uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc gccuacgucg      840

uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac accucccccc      900

ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc gaccgcggcu      960

gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc gaggucaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac ggcaagacca     1200

agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac ggcugcgacu     1260

acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac uacgucaaca     1320

agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc uacgaccccc     1380

ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag aagaucaacc     1440

agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac gccggcaagu     1500

ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc cuccucuccc     1560

ucaucgccgu cggccuccuc cucuacugca aggcccgcuc cacccccguc acccucucca     1620

aggaccagcu cuccggcauc aacaacaucg ccuucuccaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7896
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7896
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua aagcaggaac      300

ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug caccucgagg      420

gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug gucucccucu      480

cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau uacaucgaca      540

aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua gaaaccguga      600

uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu agugucaacg      660

cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug uugucccuca      720

uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac guccagaucg      780

uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua gcauauguag      840

ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau acaucucccc      900

ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg gaccguggau      960

gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc uguaagguuc     1020

agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca gaagucaauc     1080

ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc aguaaaacag     1140

auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac gggaagacca     1200

aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac ggcugugacu     1260

augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac uauguuaaua     1320

agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu uaugauccau     1380

ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag aagauuaacc     1440

agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau gcgggcaaga     1500

gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc cugcuauccc     1560

ucauagccgu cgggcugcuu uuguacugca aggcacgcuc aacacccgug acccugagua     1620

aagaucaacu cucuggaauc aauaacauug cuuucagcaa uugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7897
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7897
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc gagaccguga      600

ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc agcgugaacg      660

ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug cugagccuga      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac accagccccc      900

ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc gacagaggcu      960

gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc ugcaaggugc     1020

agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc gaggugaacc     1080

ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc agcaagaccg     1140

acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac ggcaagacca     1200

agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac uacgugaaca     1320

agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc uacgaccccc     1380

ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag aagaucaacc     1440

agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac gccggcaaga     1500

gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc cugcugagcc     1560

ugaucgccgu gggccugcug cuguacugca aggccagaag cacccccgug acccugagca     1620

aggaccagcu gagcggcauc aacaacaucg ccuucagcaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7898
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7898
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu aagcaggaac      300

uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc caccuggagg      420

gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc gugucucucu      480

ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau uacaucgaca      540

aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu gaaaccguga      600

ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg      660

ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug cucagccuga      720

uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac gugcagauug      780

ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug gcuuaugugg      840

uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau acgagccccc      900

ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc gaccgcgggu      960

gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg uguaaggugc     1020

agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc gaagugaauc     1080

ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc uccaaaacag     1140

augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac gggaagacaa     1200

aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac ggcugugacu     1260

auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac uauguuaaua     1320

agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu uaugaucccc     1380

ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag aagaucaacc     1440

agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau gccgggaagu     1500

ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc cugcuuuccc     1560

ugauugccgu gggacuccug cuguacugca aggcuagaag cacacccgug acccuuucua     1620

aagaucaacu cuccggcauc aauaacaucg cguucagcaa uugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7899
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7899
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uauuaauauu aaaagcaaac gcaaucacaa cuauacuaac agcaguaaca uucugcuuug      120

ccucagguca aaacauaaca gaggaauuuu accaauccac augcucugcu guaagcaaag      180

gauaccucgg agcauuaaga acuggauggu acaccucagu aauaacuaua gaacuaucaa      240

acauaaaaga aauaaaaugu aauggcacag acgcaaaagu gaaauuaauc aaacaagaac      300

ucgauaaaua caaaaaugcc guaaccgauc uccaacuuuu aaugcaaagc acacccgcaa      360

cagguuccgg gucagcaaua gcaagcggag uugcaguaug caaaguacua cacuuagaag      420

gagaaguaaa uaaaaucaaa ucagccuuac uaucaacaaa uaaagcaguu guaucacucu      480

caggaugcgg aguauccgua cuaacauuua aaguacuaga ucuaaaaaac uacauagaua      540

aacaacucuu accaauacua aauaaacaau cauguuccau acccaacaua gaaaccguua      600

ucgaauuuca acaaaaaaac aacagauuac uagaaaucac acgagaauuu ucaguaaaug      660

cuggagucac aacaccaguu aguacauaca ugcucaccaa uucagaacua cuaaguuuaa      720

uuaacgauau gccaauaaca aacgaccaaa aaaaacuaau gucaaauaac guacaaauag      780

uaagacaaca aucauacuca aucaugugca uaauaaaaga agaaguacua gccuauguag      840

uccaauuacc acucuacggc guaaucgaca ccccaugcug gaaauuacac acaagcccau      900

uaugcaccac caacacaaaa gaagguucaa acauuugcuu aaccagaacc gaucgaggau      960

gguacugcga uaacgcagga ucugucuccu uuuucccaca agccgaaaca ugcaaaguuc     1020

aaucaaaccg aguuuucugu gacacuauga acucacucac acuuccaagc gaaguaaacc     1080

uaugcaacgu agauauauuu aacccuaaau acgacugcaa aauaaugaca agcaaaacag     1140

acguuaguuc aucaguaauu acaagucuag gcgcaauagu gucaugcuac ggaaaaacaa     1200

aaugcaccgc auccaauaaa ugccgaggaa ucauuaaaac auucucaaac ggaugcgacu     1260

acgucagcaa uaaaggagua gacacuguuu cuguaggaaa cacccuauac uauguaaaca     1320

aacaagaagg ucaaucacua uacguaaagg gagaaccaau uauaaauuuu uacgaccccu     1380

uaguauuucc aagugaugaa uuugacgcau cuauaaguca aguuaacgaa aaaauuaacc     1440

aaucacuugc auuuauaaga aaaucagacg aacuacucca uaauguaaac gcagguaaau     1500

caacaacaaa caucaugauc acaaccauaa uaauaguaau aauuguaaua uuacuaucac     1560

uaauagcagu aggauuacua cucuacugca aagcuagauc uaccccgguc acacucucaa     1620

aagaccaauu aucuggaaua aacaauauag cauucagcaa cuaaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7900
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7900
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu uaaagccaac gccauaacca ccauccucac cgccgucacc uucugcuucg      120

cuucuggcca aaacauaacc gaagaguucu accaauccac gugcucugcc gugucaaaag      180

gcuaccucgg agcccuccgc acaggguggu acacuuccgu caucaccauc gaacucucua      240

acaucaaaga aaucaagugc aacggcacag acgcgaaagu caagcucauc aaacaagaac      300

uagacaaaua caaaaacgcc guaacagacc uccaacuccu aaugcagucc acaccagcca      360

caggcuccgg cagcgccauc gccuccggcg ucgcugucug caaaguccua caccucgaag      420

gcgaagucaa caaaaucaag ucagcccucc uuagcaccaa caaagcaguc gucucuuuaa      480

gcgggugcgg agucucuguc cuaaccuuua aaguacucga ccucaaaaac uacaucgaca      540

aacaacuacu accaauacua aacaaacaga gcugcuccau ucccaacauc gaaaccguua      600

ucgaguucca acaaaagaac aaccgccucc ucgaaaucac ccgcgaguuc uccgucaacg      660

caggcgucac caccccaguc uccaccuaua ugcuaaccaa cagcgaacuc cucagccuca      720

ucaaugacau gccaaucacc aacgaccaaa agaaacucau guccaacaac guacagauag      780

uccgccagca guccuacagc aucaugugca ucaucaaaga agaagugcuc gccuacgugg      840

uacaacuccc ucucuacgga gucauugaua cacccugcug gaaacuccac acaagccccc      900

ucugcacuac aaacaccaaa gaaggcucua acauaugccu cacccgcaca gaccgugguu      960

gguacugcga caacgccggc uccguauccu ucuuuccaca agcugaaacc ugcaaaguuc     1020

aaucaaaccg agucuucugc gacaccauga acucccucac auugcccagc gaagucaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa aaucaugacc uccaaaaccg     1140

acgucagcuc cagcgugauc acaagccuag gcgcgaucgu cagcugcuac ggcaaaacca     1200

aaugcacagc cuccaacaaa ugccgcggaa ucauaaaaac auucaguaac ggcugcgacu     1260

acguguccaa uaaaggaguc gacaccguau ccgucggaaa cacccucuac uacgucaaca     1320

aacaagaagg acaaucccuc uaugucaaag gcgaacccau uaucaacuuc uacgaccccc     1380

uaguuuuccc cuccgacgag uucgacgcaa gcauuuccca agucaacgaa aagaucaauc     1440

aaucccucgc cuucauacgc aaaagcgacg aacuacuaca caacguaaac gccggcaaaa     1500

gcaccaccaa caucaugauc acaacaauca ucaucgucau caucgucauc cuacucucac     1560

ucaucgccgu uggccuacua cucuacugca aagcccgcuc cacacccguc acccucucaa     1620

aagaccaacu cuccggcauc aacaacaucg cauucagcaa cugaggacua gugcaucaca     1680

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1740

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1800

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1860

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1980

agccaccaga auu                                                        1993


<210>  7901
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7901
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccggcugc ggcgucagcg ugcugaccuu caaggugcug      480

gaccucaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcucc      540

auccccaaca ucgagacggu gaucgaguuc cagcagaaga acaaccggcu ccuggagauc      600

acccgcgagu ucagcgugaa cgccgggguc accacccccg uguccacgua caugcugacc      660

aacagcgagc uccugucccu gaucaacgac augccgauca ccaacgacca gaagaagcuc      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggcguacgu gguccagcug ccccucuacg gcgugaucga cacccccugc      840

uggaagcugc acacgagccc ccugugcacc accaacacca aggagggguc caacaucugc      900

cucacgcgca ccgaccgggg cugguacugc gacaacgccg gcagcgucuc cuucuucccg      960

caggccgaga ccugcaaggu gcagagcaac cgcguguucu gcgacaccau gaacucccug     1020

acgcugccca gcgagguaaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgugagc uccagcguga ucaccucccu gggggccauc     1140

gucagcugcu acggcaagac gaagugcacc gccagcaaca agugccgggg gaucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaagggcg uggacaccgu guccgucggg     1260

aacacccugu acuacgugaa caagcaggag ggccagagcc ucuacgugaa gggggagccc     1320

aucaucaacu ucuacgaccc gcuggucuuc cccuccgacg aguucgacgc gagcaucucc     1380

caggugaacg agaagaucaa ccagagccug gccuucaucc gcaaguccga cgagcugcuc     1440

cacaacguga acgccggcaa gagcacgacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguga uccugcuguc ccucaucgcc guggggcugc ugcucuacug caaggcccgg     1560

agcacgcccg ucacccuguc caaggaccag cugagcggca ucaacaacau cgcguucucc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7902
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt1)

<400>  7902
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucgccuccgg cguggcggug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggucagccu cuccggcugc ggggugagcg ugcugacguu caagguccug      480

gaccucaaga acuacaucga caagcagcug cugccgaucc ucaacaagca guccugcagc      540

auccccaaca ucgagaccgu gaucgaguuc cagcagaaga acaaccggcu gcuggagauc      600

acccgcgagu ucuccgugaa cgccggcguc accacgcccg ugagcaccua caugcucacc      660

aacuccgagc ugcugagccu caucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu gguccagcuc ccgcuguacg gggugaucga cacgcccugc      840

uggaagcugc acaccagccc ccucugcacc accaacacga aggagggcuc caacaucugc      900

cugacccgca ccgaccgggg cugguacugc gacaacgcgg gguccgugag cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcguguucu gcgacacgau gaacagccug     1020

acccucccgu ccgaggucaa ccugugcaac guggacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugucc agcuccguca ucacgagccu gggcgccauc     1140

guguccugcu acgggaagac caagugcacc gccagcaaca agugccgggg caucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaaggggg ucgacacggu guccgugggc     1260

aacacccucu acuacgucaa caagcaggag gggcagagcc uguacgugaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccugguguuc ccgagcgacg aguucgacgc cuccaucagc     1380

caggucaacg agaagaucaa ccagucccuc gcguucaucc gcaagagcga cgagcugcug     1440

cacaacguga acgccgggaa guccaccacc aacaucauga ucaccacgau caucaucgug     1500

aucaucguca uccuccugag ccugaucgcc gugggccucc ugcuguacug caaggcccgg     1560

uccacccccg ugacccugag caaggaccag cucuccggca ucaacaacau cgccuucagc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7903
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt2)

<400>  7903
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccggcugc ggcgucuccg uccucaccuu caagguccuc      480

gaccucaaga acuacaucga caagcagcuc cuccccaucc ucaacaagca guccugcucc      540

auccccaaca ucgagaccgu caucgaguuc cagcagaaga acaaccgccu ccucgagauc      600

acccgcgagu ucuccgucaa cgccggcguc accacccccg ucuccaccua caugcucacc      660

aacuccgagc uccucucccu caucaacgac augcccauca ccaacgacca gaagaagcuc      720

auguccaaca acguccagau cguccgccag caguccuacu ccaucaugug caucaucaag      780

gaggaggucc ucgccuacgu cguccagcuc ccccucuacg gcgucaucga cacccccugc      840

uggaagcucc acaccucccc ccucugcacc accaacacca aggagggcuc caacaucugc      900

cucacccgca ccgaccgcgg cugguacugc gacaacgccg gcuccgucuc cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcgucuucu gcgacaccau gaacucccuc     1020

acccuccccu ccgaggucaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgucucc uccuccguca ucaccucccu cggcgccauc     1140

gucuccugcu acggcaagac caagugcacc gccuccaaca agugccgcgg caucaucaag     1200

accuucucca acggcugcga cuacgucucc aacaagggcg ucgacaccgu cuccgucggc     1260

aacacccucu acuacgucaa caagcaggag ggccaguccc ucuacgucaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccucgucuuc cccuccgacg aguucgacgc cuccaucucc     1380

caggucaacg agaagaucaa ccagucccuc gccuucaucc gcaaguccga cgagcuccuc     1440

cacaacguca acgccggcaa guccaccacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguca uccuccucuc ccucaucgcc gucggccucc uccucuacug caaggcccgc     1560

uccacccccg ucacccucuc caaggaccag cucuccggca ucaacaacau cgccuucucc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7904
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt3)

<400>  7904
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaucaaau gcaauggcac cgacgccaag      240

gugaaacuaa uaaagcagga acucgauaag uauaaaaacg caguaacuga ccugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua ucgcaucagg cguggccguc      360

uguaaggugu ugcaccucga gggugagguu aauaaaauua agagcgcucu gcugaguacg      420

aacaaagccg uggucucccu cucugggugc ggagugagcg uauuaacuuu uaagguucug      480

gaucuuaaga auuacaucga caaacaauug cugccuauuc uaaacaagca guccuguuca      540

aucccaaaua uagaaaccgu gauugaguuc cagcagaaaa acaauaggcu ccuggaaauc      600

acacgggagu uuagugucaa cgcgggcgug acuaccccgg ugagcacaua uaugcuuacc      660

aauucugagc uguugucccu cauuaacgau augcccauca cgaaugacca aaagaaacug      720

augucaaaca acguccagau cguucgccag cagagcuaca guauuaugug cauaaucaag      780

gaagaggugu uagcauaugu agugcaacug ccucucuacg gcgucauuga uacuccaugu      840

uggaaacuuc auacaucucc ccugugcacc acuaauacaa aggaaggguc caacaucugu      900

uugacccgaa cggaccgugg augguacugc gauaaugccg guagcguguc guucuuuccu      960

caggcugaga ccuguaaggu ucagucuaac agaguguucu gcgacacaau gaacucccua     1020

acucugccau cagaagucaa ucucugcaau guggauauau uuaaccccaa auaugacugu     1080

aagauuauga ccaguaaaac agauguaagc uccucuguua ucacuagccu gggcgccauc     1140

gugucaugcu acgggaagac caaauguaca gcaaguaaua agugcagggg aauuaucaag     1200

accuucucca acggcuguga cuaugucagc aauaaaggug uggacacugu cucugugggg     1260

aacacgcuuu acuauguuaa uaagcaagag ggacagucac uguacgugaa aggcgagccu     1320

auuauaaacu uuuaugaucc auugguauuc ccgagugacg aauuugaugc uagcaucucc     1380

caggucaaug agaagauuaa ccagucucuc gccuucaucc ggaaaucgga cgaacuguua     1440

cacaacguga augcgggcaa gagcacaacc aacaucauga uuacuaccau aaucauuguu     1500

aucauuguga uccugcuauc ccucauagcc gucgggcugc uuuuguacug caaggcacgc     1560

ucaacacccg ugacccugag uaaagaucaa cucucuggaa ucaauaacau ugcuuucagc     1620

aauugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7905
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt4)

<400>  7905
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcggcugc ggcgugagcg ugcugaccuu caaggugcug      480

gaccugaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcagc      540

auccccaaca ucgagaccgu gaucgaguuc cagcagaaga acaacagacu gcuggagauc      600

accagagagu ucagcgugaa cgccggcgug accacccccg ugagcaccua caugcugacc      660

aacagcgagc ugcugagccu gaucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cgugagacag cagagcuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu ggugcagcug ccccuguacg gcgugaucga cacccccugc      840

uggaagcugc acaccagccc ccugugcacc accaacacca aggagggcag caacaucugc      900

cugaccagaa ccgacagagg cugguacugc gacaacgccg gcagcgugag cuucuucccc      960

caggccgaga ccugcaaggu gcagagcaac agaguguucu gcgacaccau gaacagccug     1020

acccugccca gcgaggugaa ccugugcaac guggacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugagc agcagcguga ucaccagccu gggcgccauc     1140

gugagcugcu acggcaagac caagugcacc gccagcaaca agugcagagg caucaucaag     1200

accuucagca acggcugcga cuacgugagc aacaagggcg uggacaccgu gagcgugggc     1260

aacacccugu acuacgugaa caagcaggag ggccagagcc uguacgugaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccugguguuc cccagcgacg aguucgacgc cagcaucagc     1380

caggugaacg agaagaucaa ccagagccug gccuucauca gaaagagcga cgagcugcug     1440

cacaacguga acgccggcaa gagcaccacc aacaucauga ucaccaccau caucaucgug     1500

aucaucguga uccugcugag ccugaucgcc gugggccugc ugcuguacug caaggccaga     1560

agcacccccg ugacccugag caaggaccag cugagcggca ucaacaacau cgccuucagc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7906
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt5)

<400>  7906
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaucaaau gcaaugggac cgacgccaag      240

gugaaacuua uuaagcagga acuggauaag uauaaaaacg cugugacgga ccuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua ucgccagcgg ggucgcggug      360

uguaagguuc uccaccugga gggagaggug aauaaaauua aguccgcccu ucugagcacc      420

aacaaagcug ucgugucucu cuccggcugc ggcguuagcg ugcugacauu uaagguccuu      480

gaucugaaga auuacaucga caaacaacuc cugccuauuc ugaacaagca gucuuguucc      540

aucccgaaua uugaaaccgu gaucgaguuc cagcagaaaa acaaucggcu ccuggaaauc      600

acgcgcgagu uuagcgugaa cgccgggguc acaacccccg uuucuacaua uaugcuuacc      660

aauuccgagc ugcucagccu gauuaacgau augccuauca ccaaugacca aaagaaacuu      720

auguccaaca acgugcagau ugugagacag cagucuuaca gcaucaugug cauuaucaag      780

gaagaggucc uggcuuaugu gguucaacuc ccccuguacg gagugaucga uacaccuugu      840

uggaaacugc auacgagccc ccucugcacc acaaauacca aggaaggcag caacauuugu      900

cugacacgga ccgaccgcgg gugguacugc gauaaugccg gaucugucuc cuucuuuccu      960

caggcggaga cguguaaggu gcagagcaac agaguuuucu gcgacacaau gaacucucuu     1020

acccugccga gcgaagugaa ucucugcaau gucgauaucu uuaaccccaa auaugacugu     1080

aagauuauga ccuccaaaac agaugugucu agcuccguca ucaccagccu gggcgccauu     1140

gugucuugcu acgggaagac aaaauguacg gcuuccaaua agugccgggg aaucaucaag     1200

accuucagca acggcuguga cuauguuucu aauaaaggcg uggacacagu cuccgugggg     1260

aacacccuuu acuauguuaa uaagcaagag ggacagagcc uguacgugaa aggcgagccu     1320

auuaucaacu uuuaugaucc ccucgucuuc ccuuccgacg aauuugaugc cucuauuagc     1380

caggugaaug agaagaucaa ccagucccug gcuuucauuc gcaaaucuga cgaacugcuc     1440

cacaacguga augccgggaa guccacaacc aacaucauga uuacgaccau caucauuguu     1500

aucauuguca uccugcuuuc ccugauugcc gugggacucc ugcuguacug caaggcuaga     1560

agcacacccg ugacccuuuc uaaagaucaa cucuccggca ucaauaacau cgcguucagc     1620

aauugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7907
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt6)

<400>  7907
gggagaaagc uuaccaugga acuauuaaua uuaaaagcaa acgcaaucac aacuauacua       60

acagcaguaa cauucugcuu ugccucaggu caaaacauaa cagaggaauu uuaccaaucc      120

acaugcucug cuguaagcaa aggauaccuc ggagcauuaa gaacuggaug guacaccuca      180

guaauaacua uagaacuauc aaacauaaaa gaaauaaaau guaauggcac agacgcaaaa      240

gugaaauuaa ucaaacaaga acucgauaaa uacaaaaaug ccguaaccga ucuccaacuu      300

uuaaugcaaa gcacacccgc aacagguucc gggucagcaa uagcaagcgg aguugcagua      360

ugcaaaguac uacacuuaga aggagaagua aauaaaauca aaucagccuu acuaucaaca      420

aauaaagcag uuguaucacu cucaggaugc ggaguauccg uacuaacauu uaaaguacua      480

gaucuaaaaa acuacauaga uaaacaacuc uuaccaauac uaaauaaaca aucauguucc      540

auacccaaca uagaaaccgu uaucgaauuu caacaaaaaa acaacagauu acuagaaauc      600

acacgagaau uuucaguaaa ugcuggaguc acaacaccag uuaguacaua caugcucacc      660

aauucagaac uacuaaguuu aauuaacgau augccaauaa caaacgacca aaaaaaacua      720

augucaaaua acguacaaau aguaagacaa caaucauacu caaucaugug cauaauaaaa      780

gaagaaguac uagccuaugu aguccaauua ccacucuacg gcguaaucga caccccaugc      840

uggaaauuac acacaagccc auuaugcacc accaacacaa aagaagguuc aaacauuugc      900

uuaaccagaa ccgaucgagg augguacugc gauaacgcag gaucugucuc cuuuuuccca      960

caagccgaaa caugcaaagu ucaaucaaac cgaguuuucu gugacacuau gaacucacuc     1020

acacuuccaa gcgaaguaaa ccuaugcaac guagauauau uuaacccuaa auacgacugc     1080

aaaauaauga caagcaaaac agacguuagu ucaucaguaa uuacaagucu aggcgcaaua     1140

gugucaugcu acggaaaaac aaaaugcacc gcauccaaua aaugccgagg aaucauuaaa     1200

acauucucaa acggaugcga cuacgucagc aauaaaggag uagacacugu uucuguagga     1260

aacacccuau acuauguaaa caaacaagaa ggucaaucac uauacguaaa gggagaacca     1320

auuauaaauu uuuacgaccc cuuaguauuu ccaagugaug aauuugacgc aucuauaagu     1380

caaguuaacg aaaaaauuaa ccaaucacuu gcauuuauaa gaaaaucaga cgaacuacuc     1440

cauaauguaa acgcagguaa aucaacaaca aacaucauga ucacaaccau aauaauagua     1500

auaauuguaa uauuacuauc acuaauagca guaggauuac uacucuacug caaagcuaga     1560

ucuaccccgg ucacacucuc aaaagaccaa uuaucuggaa uaaacaauau agcauucagc     1620

aacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7908
<211>  1828
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F_DSCav1_mut8 (opt11)

<400>  7908
gggagaaagc uuaccaugga acuccucauc cuuaaagcca acgccauaac caccauccuc       60

accgccguca ccuucugcuu cgcuucuggc caaaacauaa ccgaagaguu cuaccaaucc      120

acgugcucug ccgugucaaa aggcuaccuc ggagcccucc gcacagggug guacacuucc      180

gucaucacca ucgaacucuc uaacaucaaa gaaaucaagu gcaacggcac agacgcgaaa      240

gucaagcuca ucaaacaaga acuagacaaa uacaaaaacg ccguaacaga ccuccaacuc      300

cuaaugcagu ccacaccagc cacaggcucc ggcagcgcca ucgccuccgg cgucgcuguc      360

ugcaaagucc uacaccucga aggcgaaguc aacaaaauca agucagcccu ccuuagcacc      420

aacaaagcag ucgucucuuu aagcgggugc ggagucucug uccuaaccuu uaaaguacuc      480

gaccucaaaa acuacaucga caaacaacua cuaccaauac uaaacaaaca gagcugcucc      540

auucccaaca ucgaaaccgu uaucgaguuc caacaaaaga acaaccgccu ccucgaaauc      600

acccgcgagu ucuccgucaa cgcaggcguc accaccccag ucuccaccua uaugcuaacc      660

aacagcgaac uccucagccu caucaaugac augccaauca ccaacgacca aaagaaacuc      720

auguccaaca acguacagau aguccgccag caguccuaca gcaucaugug caucaucaaa      780

gaagaagugc ucgccuacgu gguacaacuc ccucucuacg gagucauuga uacacccugc      840

uggaaacucc acacaagccc ccucugcacu acaaacacca aagaaggcuc uaacauaugc      900

cucacccgca cagaccgugg uugguacugc gacaacgccg gcuccguauc cuucuuucca      960

caagcugaaa ccugcaaagu ucaaucaaac cgagucuucu gcgacaccau gaacucccuc     1020

acauugccca gcgaagucaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aaaaucauga ccuccaaaac cgacgucagc uccagcguga ucacaagccu aggcgcgauc     1140

gucagcugcu acggcaaaac caaaugcaca gccuccaaca aaugccgcgg aaucauaaaa     1200

acauucagua acggcugcga cuacgugucc aauaaaggag ucgacaccgu auccgucgga     1260

aacacccucu acuacgucaa caaacaagaa ggacaauccc ucuaugucaa aggcgaaccc     1320

auuaucaacu ucuacgaccc ccuaguuuuc cccuccgacg aguucgacgc aagcauuucc     1380

caagucaacg aaaagaucaa ucaaucccuc gccuucauac gcaaaagcga cgaacuacua     1440

cacaacguaa acgccggcaa aagcaccacc aacaucauga ucacaacaau caucaucguc     1500

aucaucguca uccuacucuc acucaucgcc guuggccuac uacucuacug caaagcccgc     1560

uccacacccg ucacccucuc aaaagaccaa cucuccggca ucaacaacau cgcauucagc     1620

aacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1680

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1800

aaaggcucuu uucagagcca ccagaauu                                        1828


<210>  7909
<211>  515
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (artificial) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7909

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Gly Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Asp Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Gly Ser Gly Ser Ala Ile Ala Ser Gly 
            100                 105                 110         


Val Ala Val Cys Lys Val Leu His Leu Glu Gly Glu Val Asn Lys Ile 
        115                 120                 125             


Lys Ser Ala Leu Leu Ser Thr Asn Lys Ala Val Val Ser Leu Ser Gly 
    130                 135                 140                 


Cys Gly Val Ser Val Leu Thr Phe Lys Val Leu Asp Leu Lys Asn Tyr 
145                 150                 155                 160 


Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn Lys Gln Ser Cys Ser Ile 
                165                 170                 175     


Pro Asn Ile Glu Thr Val Ile Glu Phe Gln Gln Lys Asn Asn Arg Leu 
            180                 185                 190         


Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala Gly Val Thr Thr Pro 
        195                 200                 205             


Val Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu Leu Ser Leu Ile Asn 
    210                 215                 220                 


Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu Met Ser Asn Asn Val 
225                 230                 235                 240 


Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met Cys Ile Ile Lys Glu 
                245                 250                 255     


Glu Val Leu Ala Tyr Val Val Gln Leu Pro Leu Tyr Gly Val Ile Asp 
            260                 265                 270         


Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu Cys Thr Thr Asn Thr 
        275                 280                 285             


Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr Asp Arg Gly Trp Tyr 
    290                 295                 300                 


Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro Gln Ala Glu Thr Cys 
305                 310                 315                 320 


Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr Met Asn Ser Leu Thr 
                325                 330                 335     


Leu Pro Ser Glu Val Asn Leu Cys Asn Val Asp Ile Phe Asn Pro Lys 
            340                 345                 350         


Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp Val Ser Ser Ser Val 
        355                 360                 365             


Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr Gly Lys Thr Lys Cys 
    370                 375                 380                 


Thr Ala Ser Asn Lys Cys Arg Gly Ile Ile Lys Thr Phe Ser Asn Gly 
385                 390                 395                 400 


Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr Val Ser Val Gly Asn 
                405                 410                 415     


Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly Gln Ser Leu Tyr Val Lys 
            420                 425                 430         


Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro Leu Val Phe Pro Ser Asp 
        435                 440                 445             


Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu Lys Ile Asn Gln Ser 
    450                 455                 460                 


Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu Leu His Asn Val Asn Ala 
465                 470                 475                 480 


Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Thr Ile Ile Ile Val Ile 
                485                 490                 495     


Ile Val Ile Leu Leu Ser Leu Ile Ala Val Gly Leu Leu Leu Tyr Cys 
            500                 505                 510         


Lys Ala Arg 
        515 


<210>  7910
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7910
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcggacc ggcugguaca ccuccgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac gggaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcaguccacc      300

ccggcaaccg gcuccggcuc cgccaucgcg agcggcgucg ccgugugcaa ggugcugcac      360

cucgaggggg aggucaacaa gaucaagagc gcccugcugu ccaccaacaa ggccguggug      420

agccucuccg gcugcggcgu cagcgugcug accuucaagg ugcuggaccu caagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcuccauccc caacaucgag      540

acggugaucg aguuccagca gaagaacaac cggcuccugg agaucacccg cgaguucagc      600

gugaacgccg gggucaccac ccccgugucc acguacaugc ugaccaacag cgagcuccug      660

ucccugauca acgacaugcc gaucaccaac gaccagaaga agcucaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcg      780

uacguggucc agcugccccu cuacggcgug aucgacaccc ccugcuggaa gcugcacacg      840

agcccccugu gcaccaccaa caccaaggag ggguccaaca ucugccucac gcgcaccgac      900

cggggcuggu acugcgacaa cgccggcagc gucuccuucu ucccgcaggc cgagaccugc      960

aaggugcaga gcaaccgcgu guucugcgac accaugaacu cccugacgcu gcccagcgag     1020

guaaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ugagcuccag cgugaucacc ucccuggggg ccaucgucag cugcuacggc     1140

aagacgaagu gcaccgccag caacaagugc cgggggauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accguguccg ucgggaacac ccuguacuac     1260

gugaacaagc aggagggcca gagccucuac gugaaggggg agcccaucau caacuucuac     1320

gacccgcugg ucuuccccuc cgacgaguuc gacgcgagca ucucccaggu gaacgagaag     1380

aucaaccaga gccuggccuu cauccgcaag uccgacgagc ugcuccacaa cgugaacgcc     1440

ggcaagagca cgaccaacau caugaucacc accaucauca ucgucaucau cgugauccug     1500

cugucccuca ucgccguggg gcugcugcuc uacugcaagg cccgguga                  1548


<210>  7911
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7911
auggagcugc ucauccugaa ggccaacgcc aucaccacca uccugacggc ggugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc aguccacgug cagcgccguc      120

uccaaggggu accucggcgc ccugcgcacc gggugguaca ccagcgugau caccaucgag      180

cuguccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcucaucaag      240

caggagcugg acaaguacaa gaacgcgguc acggaccugc agcuccugau gcagagcacc      300

cccgccaccg gguccggcag cgccaucgcc uccggcgugg cggugugcaa gguccugcac      360

cucgaggggg aggugaacaa gaucaagagc gcccugcugu ccaccaacaa ggccgugguc      420

agccucuccg gcugcggggu gagcgugcug acguucaagg uccuggaccu caagaacuac      480

aucgacaagc agcugcugcc gauccucaac aagcaguccu gcagcauccc caacaucgag      540

accgugaucg aguuccagca gaagaacaac cggcugcugg agaucacccg cgaguucucc      600

gugaacgccg gcgucaccac gcccgugagc accuacaugc ucaccaacuc cgagcugcug      660

agccucauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucgucc ggcagcaguc cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggucc agcucccgcu guacggggug aucgacacgc ccugcuggaa gcugcacacc      840

agcccccucu gcaccaccaa cacgaaggag ggcuccaaca ucugccugac ccgcaccgac      900

cggggcuggu acugcgacaa cgcggggucc gugagcuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu guucugcgac acgaugaaca gccugacccu cccguccgag     1020

gucaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1080

aagaccgacg uguccagcuc cgucaucacg agccugggcg ccaucguguc cugcuacggg     1140

aagaccaagu gcaccgccag caacaagugc cggggcauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ugagcaacaa gggggucgac acgguguccg ugggcaacac ccucuacuac     1260

gucaacaagc aggaggggca gagccuguac gugaagggcg agcccaucau caacuucuac     1320

gacccccugg uguucccgag cgacgaguuc gacgccucca ucagccaggu caacgagaag     1380

aucaaccagu cccucgcguu cauccgcaag agcgacgagc ugcugcacaa cgugaacgcc     1440

gggaagucca ccaccaacau caugaucacc acgaucauca ucgugaucau cgucauccuc     1500

cugagccuga ucgccguggg ccuccugcug uacugcaagg cccgguga                  1548


<210>  7912
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7912
auggagcucc ucauccucaa ggccaacgcc aucaccacca uccucaccgc cgucaccuuc       60

ugcuucgccu ccggccagaa caucaccgag gaguucuacc aguccaccug cuccgccguc      120

uccaagggcu accucggcgc ccuccgcacc ggcugguaca ccuccgucau caccaucgag      180

cucuccaaca ucaaggagau caagugcaac ggcaccgacg ccaaggucaa gcucaucaag      240

caggagcucg acaaguacaa gaacgccguc accgaccucc agcuccucau gcaguccacc      300

cccgccaccg gcuccggcuc cgccaucgcc uccggcgucg ccgucugcaa gguccuccac      360

cucgagggcg aggucaacaa gaucaagucc gcccuccucu ccaccaacaa ggccgucguc      420

ucccucuccg gcugcggcgu cuccguccuc accuucaagg uccucgaccu caagaacuac      480

aucgacaagc agcuccuccc cauccucaac aagcaguccu gcuccauccc caacaucgag      540

accgucaucg aguuccagca gaagaacaac cgccuccucg agaucacccg cgaguucucc      600

gucaacgccg gcgucaccac ccccgucucc accuacaugc ucaccaacuc cgagcuccuc      660

ucccucauca acgacaugcc caucaccaac gaccagaaga agcucauguc caacaacguc      720

cagaucgucc gccagcaguc cuacuccauc augugcauca ucaaggagga gguccucgcc      780

uacgucgucc agcucccccu cuacggcguc aucgacaccc ccugcuggaa gcuccacacc      840

uccccccucu gcaccaccaa caccaaggag ggcuccaaca ucugccucac ccgcaccgac      900

cgcggcuggu acugcgacaa cgccggcucc gucuccuucu ucccccaggc cgagaccugc      960

aagguccagu ccaaccgcgu cuucugcgac accaugaacu cccucacccu ccccuccgag     1020

gucaaccucu gcaacgucga caucuucaac cccaaguacg acugcaagau caugaccucc     1080

aagaccgacg ucuccuccuc cgucaucacc ucccucggcg ccaucgucuc cugcuacggc     1140

aagaccaagu gcaccgccuc caacaagugc cgcggcauca ucaagaccuu cuccaacggc     1200

ugcgacuacg ucuccaacaa gggcgucgac accgucuccg ucggcaacac ccucuacuac     1260

gucaacaagc aggagggcca gucccucuac gucaagggcg agcccaucau caacuucuac     1320

gacccccucg ucuuccccuc cgacgaguuc gacgccucca ucucccaggu caacgagaag     1380

aucaaccagu cccucgccuu cauccgcaag uccgacgagc uccuccacaa cgucaacgcc     1440

ggcaagucca ccaccaacau caugaucacc accaucauca ucgucaucau cgucauccuc     1500

cucucccuca ucgccgucgg ccuccuccuc uacugcaagg cccgcuga                  1548


<210>  7913
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7913
auggagcugc ucauccuuaa ggccaacgcu auuaccacaa uacugacugc agugacguuc       60

ugcuuugcca gcggccagaa uaucaccgaa gaguucuacc aauccacaug uucugcgguc      120

ucaaaagggu auuugggagc uuuaagaacu gguugguaca ccaguguuau uacaaucgaa      180

cugagcaaca uuaaggagau caaaugcaau ggcaccgacg ccaaggugaa acuaauaaag      240

caggaacucg auaaguauaa aaacgcagua acugaccugc agcuucugau gcaguccaca      300

cccgccaccg ggucuggauc ggcuaucgca ucaggcgugg ccgucuguaa gguguugcac      360

cucgagggug agguuaauaa aauuaagagc gcucugcuga guacgaacaa agccgugguc      420

ucccucucug ggugcggagu gagcguauua acuuuuaagg uucuggaucu uaagaauuac      480

aucgacaaac aauugcugcc uauucuaaac aagcaguccu guucaauccc aaauauagaa      540

accgugauug aguuccagca gaaaaacaau aggcuccugg aaaucacacg ggaguuuagu      600

gucaacgcgg gcgugacuac cccggugagc acauauaugc uuaccaauuc ugagcuguug      660

ucccucauua acgauaugcc caucacgaau gaccaaaaga aacugauguc aaacaacguc      720

cagaucguuc gccagcagag cuacaguauu augugcauaa ucaaggaaga gguguuagca      780

uauguagugc aacugccucu cuacggcguc auugauacuc cauguuggaa acuucauaca      840

ucuccccugu gcaccacuaa uacaaaggaa ggguccaaca ucuguuugac ccgaacggac      900

cguggauggu acugcgauaa ugccgguagc gugucguucu uuccucaggc ugagaccugu      960

aagguucagu cuaacagagu guucugcgac acaaugaacu cccuaacucu gccaucagaa     1020

gucaaucucu gcaaugugga uauauuuaac cccaaauaug acuguaagau uaugaccagu     1080

aaaacagaug uaagcuccuc uguuaucacu agccugggcg ccaucguguc augcuacggg     1140

aagaccaaau guacagcaag uaauaagugc aggggaauua ucaagaccuu cuccaacggc     1200

ugugacuaug ucagcaauaa agguguggac acugucucug uggggaacac gcuuuacuau     1260

guuaauaagc aagagggaca gucacuguac gugaaaggcg agccuauuau aaacuuuuau     1320

gauccauugg uauucccgag ugacgaauuu gaugcuagca ucucccaggu caaugagaag     1380

auuaaccagu cucucgccuu cauccggaaa ucggacgaac uguuacacaa cgugaaugcg     1440

ggcaagagca caaccaacau caugauuacu accauaauca uuguuaucau ugugauccug     1500

cuaucccuca uagccgucgg gcugcuuuug uacugcaagg cacgcuga                  1548


<210>  7914
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7914
auggagcugc ugauccugaa ggccaacgcc aucaccacca uccugaccgc cgugaccuuc       60

ugcuucgcca gcggccagaa caucaccgag gaguucuacc agagcaccug cagcgccgug      120

agcaagggcu accugggcgc ccugagaacc ggcugguaca ccagcgugau caccaucgag      180

cugagcaaca ucaaggagau caagugcaac ggcaccgacg ccaaggugaa gcugaucaag      240

caggagcugg acaaguacaa gaacgccgug accgaccugc agcugcugau gcagagcacc      300

cccgccaccg gcagcggcag cgccaucgcc agcggcgugg ccgugugcaa ggugcugcac      360

cuggagggcg aggugaacaa gaucaagagc gcccugcuga gcaccaacaa ggccguggug      420

agccugagcg gcugcggcgu gagcgugcug accuucaagg ugcuggaccu gaagaacuac      480

aucgacaagc agcugcugcc cauccugaac aagcagagcu gcagcauccc caacaucgag      540

accgugaucg aguuccagca gaagaacaac agacugcugg agaucaccag agaguucagc      600

gugaacgccg gcgugaccac ccccgugagc accuacaugc ugaccaacag cgagcugcug      660

agccugauca acgacaugcc caucaccaac gaccagaaga agcugaugag caacaacgug      720

cagaucguga gacagcagag cuacagcauc augugcauca ucaaggagga ggugcuggcc      780

uacguggugc agcugccccu guacggcgug aucgacaccc ccugcuggaa gcugcacacc      840

agcccccugu gcaccaccaa caccaaggag ggcagcaaca ucugccugac cagaaccgac      900

agaggcuggu acugcgacaa cgccggcagc gugagcuucu ucccccaggc cgagaccugc      960

aaggugcaga gcaacagagu guucugcgac accaugaaca gccugacccu gcccagcgag     1020

gugaaccugu gcaacgugga caucuucaac cccaaguacg acugcaagau caugaccagc     1080

aagaccgacg ugagcagcag cgugaucacc agccugggcg ccaucgugag cugcuacggc     1140

aagaccaagu gcaccgccag caacaagugc agaggcauca ucaagaccuu cagcaacggc     1200

ugcgacuacg ugagcaacaa gggcguggac accgugagcg ugggcaacac ccuguacuac     1260

gugaacaagc aggagggcca gagccuguac gugaagggcg agcccaucau caacuucuac     1320

gacccccugg uguuccccag cgacgaguuc gacgccagca ucagccaggu gaacgagaag     1380

aucaaccaga gccuggccuu caucagaaag agcgacgagc ugcugcacaa cgugaacgcc     1440

ggcaagagca ccaccaacau caugaucacc accaucauca ucgugaucau cgugauccug     1500

cugagccuga ucgccguggg ccugcugcug uacugcaagg ccagauga                  1548


<210>  7915
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7915
auggagcugc ucauccugaa ggccaacgcu auuaccacaa uccuuacggc cgugaccuuc       60

ugcuuugcga gcggccagaa uauuacagaa gaguucuacc aauccaccug uucugcuguc      120

agcaaagggu aucugggagc ccucagaaca ggcugguaca ccuccguuau cacaauugaa      180

cugucuaaca ucaaggagau caaaugcaau gggaccgacg ccaaggugaa acuuauuaag      240

caggaacugg auaaguauaa aaacgcugug acggaccucc agcugcugau gcagagcacc      300

cccgccacag gauccggcuc ugcuaucgcc agcggggucg cgguguguaa gguucuccac      360

cuggagggag aggugaauaa aauuaagucc gcccuucuga gcaccaacaa agcugucgug      420

ucucucuccg gcugcggcgu uagcgugcug acauuuaagg uccuugaucu gaagaauuac      480

aucgacaaac aacuccugcc uauucugaac aagcagucuu guuccauccc gaauauugaa      540

accgugaucg aguuccagca gaaaaacaau cggcuccugg aaaucacgcg cgaguuuagc      600

gugaacgccg gggucacaac ccccguuucu acauauaugc uuaccaauuc cgagcugcuc      660

agccugauua acgauaugcc uaucaccaau gaccaaaaga aacuuauguc caacaacgug      720

cagauuguga gacagcaguc uuacagcauc augugcauua ucaaggaaga gguccuggcu      780

uaugugguuc aacucccccu guacggagug aucgauacac cuuguuggaa acugcauacg      840

agcccccucu gcaccacaaa uaccaaggaa ggcagcaaca uuugucugac acggaccgac      900

cgcggguggu acugcgauaa ugccggaucu gucuccuucu uuccucaggc ggagacgugu      960

aaggugcaga gcaacagagu uuucugcgac acaaugaacu cucuuacccu gccgagcgaa     1020

gugaaucucu gcaaugucga uaucuuuaac cccaaauaug acuguaagau uaugaccucc     1080

aaaacagaug ugucuagcuc cgucaucacc agccugggcg ccauuguguc uugcuacggg     1140

aagacaaaau guacggcuuc caauaagugc cggggaauca ucaagaccuu cagcaacggc     1200

ugugacuaug uuucuaauaa aggcguggac acagucuccg uggggaacac ccuuuacuau     1260

guuaauaagc aagagggaca gagccuguac gugaaaggcg agccuauuau caacuuuuau     1320

gauccccucg ucuucccuuc cgacgaauuu gaugccucua uuagccaggu gaaugagaag     1380

aucaaccagu cccuggcuuu cauucgcaaa ucugacgaac ugcuccacaa cgugaaugcc     1440

gggaagucca caaccaacau caugauuacg accaucauca uuguuaucau ugucauccug     1500

cuuucccuga uugccguggg acuccugcug uacugcaagg cuagauga                  1548


<210>  7916
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7916
auggaacuac ucauauugaa agccaacgca aucacaacaa uacuaaccgc cguaacauuu       60

ugcuucgcgu caggccaaaa uauaacagaa gaauuuuacc aaucaacaug cuccgccgua      120

ucaaaaggau accuaggugc auuacgaacc gguugguaca caucaguaau cacaauagaa      180

cuuuccaaca uuaaagaaau aaaaugcaau ggcacagacg caaaagucaa acuaauaaaa      240

caagaacuag acaaauauaa aaacgccguc acagacuuac aacuauuaau gcaaagcaca      300

ccagcaacag gauccggauc agcaauagca ucaggaguag ccgucuguaa aguacuacac      360

cuagaaggcg aaguuaauaa aauuaaauca gcuuuauuau caaccaacaa agcaguagua      420

ucacuauccg gaugcggagu cuccguccua acauucaaag uacuagaccu caagaauuac      480

auagauaaac aacuacuacc aauacucaac aaacaaucau guucaauacc aaacaucgaa      540

accgucauag aauuucaaca aaaaaauaau agacucuuag aaauaacacg agaauuuagc      600

guaaacgcag gagucacaac cccugucuca acauacaugc uaaccaauuc cgaauuauua      660

ucacucauaa augacaugcc aauaacuaau gaccaaaaaa aacuuauguc aaacaacgua      720

caaauaguaa gacaacaauc auauucaaua augugcauaa ucaaagaaga aguuuuagca      780

uauguaguac aacuaccacu auauggcguc auagacacac caugcuggaa auuacacaca      840

ucaccucuau gcacaacaaa cacaaaagaa ggaagcaaca uuugccuaac cagaaccgau      900

agaggauggu acugcgauaa cgcaggcuca guaucauucu ucccucaagc cgaaacuugc      960

aaaguccaau caaauagagu cuucugcgau acaaugaacu ccuuaacuuu accaucagaa     1020

guaaaucuau gcaacguaga uaucuuuaau ccaaaauacg auugcaaaau caugacauca     1080

aaaacagaug uaucaucuag uguaauuacc ucccuaggag caauaguaag cugcuacgga     1140

aaaacaaaau gcaccgccuc uaacaaaugu cguggaauaa uaaaaacauu cucaaacgga     1200

ugcgauuaug uaucaaauaa aggugucgac accguaucag uaggcaauac acuauacuau     1260

guaaauaaac aagaaggaca aucacucuac gucaaaggug aaccaauaau aaacuucuac     1320

gacccacuug uauucccaag cgacgaauuu gacgcaucaa uaagccaagu aaacgaaaaa     1380

auaaaccaau cacuagcauu caucagaaaa ucagacgaac uacuccacaa uguaaaugca     1440

ggaaaaucaa caaccaauau caugauaaca accauaauaa uagucauaau aguaauacua     1500

uuaucccuca uagccguugg acuacuccua uauuguaaag cacgauaa                  1548


<210>  7917
<211>  1548
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__F-del_DSCav1_mut8

<400>  7917
auggaacucc ucauccucaa agccaacgcc aucaccacca uacucaccgc aguaaccuuc       60

ugcuucgcau ccggccaaaa caucacagaa gaguucuacc agaguaccug cuccgccguc      120

uccaaaggcu accuuggcgc ccuccguacc gggugguaca cauccgucau cacaaucgaa      180

cucuccaaca ucaaagaaau aaagugcaac ggcacagacg ccaaaguaaa acugauaaag      240

caagaacucg acaaauacaa aaacgccgua accgaccucc agcuacuaau gcaauccacu      300

cccgccaccg gcagcggauc cgccaucgcc uccggaguag ccgucuguaa agucuuacac      360

cucgaaggcg aagugaacaa aaucaaaucc gcccuacucu caaccaacaa agccguagua      420

ucacucuccg ggugcggcgu uucagugcua acguucaaag uccuugaccu caaaaacuac      480

aucgacaaac aacuccuccc cauccuaaau aaacaauccu gcuccauacc caacaucgag      540

acugucaucg aguuccagca gaaaaacaac cgacuccucg aaaucacacg cgaguucucu      600

gucaacgccg gcgucacaac ccccgucucc acauacaugc ucaccaacag cgaacuccuc      660

ucccuaauca augacaugcc caucaccaac gaccaaaaga aacucauguc aaacaacguc      720

caaaucgucc gccaacaauc cuacagcauc augugcauca ucaaagaaga aguucucgca      780

uacguaguac aacucccccu cuacggagug aucgacaccc ccugcuggaa acuacacacc      840

agcccgcuuu gcaccacaaa caccaaggaa ggcuccaaca ucugccucac ucgaaccgac      900

cgcggcuggu acugcgacaa cgcaggcucc gucaguuucu uuccccaagc agaaacaugc      960

aaaguccaau ccaaccgagu auucugcgac accaugaacu cccucacccu accauccgaa     1020

guuaaccuau gcaacgugga caucuucaac cccaaguacg acugcaaaau uaugaccucc     1080

aaaaccgacg uauccuccag cgucaucacc agccucggag caauagucuc cugcuacggc     1140

aagaccaagu gcaccgcuuc caacaagugu cgcggaauca ucaaaaccuu cucaaacggc     1200

ugcgacuacg ucuccaacaa aggcgucgac accguauccg uaggaaacac ccuauacuac     1260

gucaacaaac aagaaggaca aucccucuau gucaaaggcg aacccaucau caauuucuac     1320

gacccccuag ucuucccuuc cgacgaguuc gacgcgucca ucagccaagu caaugaaaag     1380

aucaaccaga gccuggcauu cauccgcaaa uccgacgaac uccuccacaa cgucaacgcg     1440

ggaaaaucca cgacaaacau caugaucacc accaucauca ucgucaucau agucauucuc     1500

cuuucucuca ucgccguggg acuacuucuc uacugcaaag cccgauaa                  1548


<210>  7918
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7918
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7919
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7919
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

ggugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7920
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7920
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7921
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7921
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7922
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7922
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7923
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7923
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7924
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7924
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauugaaagc caacgcaauc acaacaauac      120

uaaccgccgu aacauuuugc uucgcgucag gccaaaauau aacagaagaa uuuuaccaau      180

caacaugcuc cgccguauca aaaggauacc uaggugcauu acgaaccggu ugguacacau      240

caguaaucac aauagaacuu uccaacauua aagaaauaaa augcaauggc acagacgcaa      300

aagucaaacu aauaaaacaa gaacuagaca aauauaaaaa cgccgucaca gacuuacaac      360

uauuaaugca aagcacacca gcaacaggau ccggaucagc aauagcauca ggaguagccg      420

ucuguaaagu acuacaccua gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa      480

ccaacaaagc aguaguauca cuauccggau gcggagucuc cguccuaaca uucaaaguac      540

uagaccucaa gaauuacaua gauaaacaac uacuaccaau acucaacaaa caaucauguu      600

caauaccaaa caucgaaacc gucauagaau uucaacaaaa aaauaauaga cucuuagaaa      660

uaacacgaga auuuagcgua aacgcaggag ucacaacccc ugucucaaca uacaugcuaa      720

ccaauuccga auuauuauca cucauaaaug acaugccaau aacuaaugac caaaaaaaac      780

uuaugucaaa caacguacaa auaguaagac aacaaucaua uucaauaaug ugcauaauca      840

aagaagaagu uuuagcauau guaguacaac uaccacuaua uggcgucaua gacacaccau      900

gcuggaaauu acacacauca ccucuaugca caacaaacac aaaagaagga agcaacauuu      960

gccuaaccag aaccgauaga ggaugguacu gcgauaacgc aggcucagua ucauucuucc     1020

cucaagccga aacuugcaaa guccaaucaa auagagucuu cugcgauaca augaacuccu     1080

uaacuuuacc aucagaagua aaucuaugca acguagauau cuuuaaucca aaauacgauu     1140

gcaaaaucau gacaucaaaa acagauguau caucuagugu aauuaccucc cuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa     1260

aaacauucuc aaacggaugc gauuauguau caaauaaagg ugucgacacc guaucaguag     1320

gcaauacacu auacuaugua aauaaacaag aaggacaauc acucuacguc aaaggugaac     1380

caauaauaaa cuucuacgac ccacuuguau ucccaagcga cgaauuugac gcaucaauaa     1440

gccaaguaaa cgaaaaaaua aaccaaucac uagcauucau cagaaaauca gacgaacuac     1500

uccacaaugu aaaugcagga aaaucaacaa ccaauaucau gauaacaacc auaauaauag     1560

ucauaauagu aauacuauua ucccucauag ccguuggacu acuccuauau uguaaagcac     1620

gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7925
<211>  1824
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7925
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccauc accaccauac      120

ucaccgcagu aaccuucugc uucgcauccg gccaaaacau cacagaagag uucuaccaga      180

guaccugcuc cgccgucucc aaaggcuacc uuggcgcccu ccguaccggg ugguacacau      240

ccgucaucac aaucgaacuc uccaacauca aagaaauaaa gugcaacggc acagacgcca      300

aaguaaaacu gauaaagcaa gaacucgaca aauacaaaaa cgccguaacc gaccuccagc      360

uacuaaugca auccacuccc gccaccggca gcggauccgc caucgccucc ggaguagccg      420

ucuguaaagu cuuacaccuc gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc cguaguauca cucuccgggu gcggcguuuc agugcuaacg uucaaagucc      540

uugaccucaa aaacuacauc gacaaacaac uccuccccau ccuaaauaaa caauccugcu      600

ccauacccaa caucgagacu gucaucgagu uccagcagaa aaacaaccga cuccucgaaa      660

ucacacgcga guucucuguc aacgccggcg ucacaacccc cgucuccaca uacaugcuca      720

ccaacagcga acuccucucc cuaaucaaug acaugcccau caccaacgac caaaagaaac      780

ucaugucaaa caacguccaa aucguccgcc aacaauccua cagcaucaug ugcaucauca      840

aagaagaagu ucucgcauac guaguacaac ucccccucua cggagugauc gacacccccu      900

gcuggaaacu acacaccagc ccgcuuugca ccacaaacac caaggaaggc uccaacaucu      960

gccucacucg aaccgaccgc ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc     1020

cccaagcaga aacaugcaaa guccaaucca accgaguauu cugcgacacc augaacuccc     1080

ucacccuacc auccgaaguu aaccuaugca acguggacau cuucaacccc aaguacgacu     1140

gcaaaauuau gaccuccaaa accgacguau ccuccagcgu caucaccagc cucggagcaa     1200

uagucuccug cuacggcaag accaagugca ccgcuuccaa caagugucgc ggaaucauca     1260

aaaccuucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacacc guauccguag     1320

gaaacacccu auacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccaucaucaa uuucuacgac ccccuagucu ucccuuccga cgaguucgac gcguccauca     1440

gccaagucaa ugaaaagauc aaccagagcc uggcauucau ccgcaaaucc gacgaacucc     1500

uccacaacgu caacgcggga aaauccacga caaacaucau gaucaccacc aucaucaucg     1560

ucaucauagu cauucuccuu ucucucaucg ccgugggacu acuucucuac ugcaaagccc     1620

gauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1680

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1800

gcucuuuuca gagccaccag aauu                                            1824


<210>  7926
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7926
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7927
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7927
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7928
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7928
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7929
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7929
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cugaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7930
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7930
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7931
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7931
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag augaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7932
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7932
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auugaaagcc      120

aacgcaauca caacaauacu aaccgccgua acauuuugcu ucgcgucagg ccaaaauaua      180

acagaagaau uuuaccaauc aacaugcucc gccguaucaa aaggauaccu aggugcauua      240

cgaaccgguu gguacacauc aguaaucaca auagaacuuu ccaacauuaa agaaauaaaa      300

ugcaauggca cagacgcaaa agucaaacua auaaaacaag aacuagacaa auauaaaaac      360

gccgucacag acuuacaacu auuaaugcaa agcacaccag caacaggauc cggaucagca      420

auagcaucag gaguagccgu cuguaaagua cuacaccuag aaggcgaagu uaauaaaauu      480

aaaucagcuu uauuaucaac caacaaagca guaguaucac uauccggaug cggagucucc      540

guccuaacau ucaaaguacu agaccucaag aauuacauag auaaacaacu acuaccaaua      600

cucaacaaac aaucauguuc aauaccaaac aucgaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac ucuuagaaau aacacgagaa uuuagcguaa acgcaggagu cacaaccccu      720

gucucaacau acaugcuaac caauuccgaa uuauuaucac ucauaaauga caugccaaua      780

acuaaugacc aaaaaaaacu uaugucaaac aacguacaaa uaguaagaca acaaucauau      840

ucaauaaugu gcauaaucaa agaagaaguu uuagcauaug uaguacaacu accacuauau      900

ggcgucauag acacaccaug cuggaaauua cacacaucac cucuaugcac aacaaacaca      960

aaagaaggaa gcaacauuug ccuaaccaga accgauagag gaugguacug cgauaacgca     1020

ggcucaguau cauucuuccc ucaagccgaa acuugcaaag uccaaucaaa uagagucuuc     1080

ugcgauacaa ugaacuccuu aacuuuacca ucagaaguaa aucuaugcaa cguagauauc     1140

uuuaauccaa aauacgauug caaaaucaug acaucaaaaa cagauguauc aucuagugua     1200

auuaccuccc uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucuaac     1260

aaaugucgug gaauaauaaa aacauucuca aacggaugcg auuauguauc aaauaaaggu     1320

gucgacaccg uaucaguagg caauacacua uacuauguaa auaaacaaga aggacaauca     1380

cucuacguca aaggugaacc aauaauaaac uucuacgacc cacuuguauu cccaagcgac     1440

gaauuugacg caucaauaag ccaaguaaac gaaaaaauaa accaaucacu agcauucauc     1500

agaaaaucag acgaacuacu ccacaaugua aaugcaggaa aaucaacaac caauaucaug     1560

auaacaacca uaauaauagu cauaauagua auacuauuau cccucauagc cguuggacua     1620

cuccuauauu guaaagcacg auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7933
<211>  1843
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7933
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauca ccaccauacu caccgcagua accuucugcu ucgcauccgg ccaaaacauc      180

acagaagagu ucuaccagag uaccugcucc gccgucucca aaggcuaccu uggcgcccuc      240

cguaccgggu gguacacauc cgucaucaca aucgaacucu ccaacaucaa agaaauaaag      300

ugcaacggca cagacgccaa aguaaaacug auaaagcaag aacucgacaa auacaaaaac      360

gccguaaccg accuccagcu acuaaugcaa uccacucccg ccaccggcag cggauccgcc      420

aucgccuccg gaguagccgu cuguaaaguc uuacaccucg aaggcgaagu gaacaaaauc      480

aaauccgccc uacucucaac caacaaagcc guaguaucac ucuccgggug cggcguuuca      540

gugcuaacgu ucaaaguccu ugaccucaaa aacuacaucg acaaacaacu ccuccccauc      600

cuaaauaaac aauccugcuc cauacccaac aucgagacug ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau cacacgcgag uucucuguca acgccggcgu cacaaccccc      720

gucuccacau acaugcucac caacagcgaa cuccucuccc uaaucaauga caugcccauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgcca acaauccuac      840

agcaucaugu gcaucaucaa agaagaaguu cucgcauacg uaguacaacu cccccucuac      900

ggagugaucg acacccccug cuggaaacua cacaccagcc cgcuuugcac cacaaacacc      960

aaggaaggcu ccaacaucug ccucacucga accgaccgcg gcugguacug cgacaacgca     1020

ggcuccguca guuucuuucc ccaagcagaa acaugcaaag uccaauccaa ccgaguauuc     1080

ugcgacacca ugaacucccu cacccuacca uccgaaguua accuaugcaa cguggacauc     1140

uucaacccca aguacgacug caaaauuaug accuccaaaa ccgacguauc cuccagcguc     1200

aucaccagcc ucggagcaau agucuccugc uacggcaaga ccaagugcac cgcuuccaac     1260

aagugucgcg gaaucaucaa aaccuucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacaccg uauccguagg aaacacccua uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc caucaucaau uucuacgacc cccuagucuu cccuuccgac     1440

gaguucgacg cguccaucag ccaagucaau gaaaagauca accagagccu ggcauucauc     1500

cgcaaauccg acgaacuccu ccacaacguc aacgcgggaa aauccacgac aaacaucaug     1560

aucaccacca ucaucaucgu caucauaguc auucuccuuu cucucaucgc cgugggacua     1620

cuucucuacu gcaaagcccg auaaggacua gucccuguuc ccagagccca cuuuuuuuuc     1680

uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1800

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1843


<210>  7934
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7934
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7935
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7935
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7936
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7936
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7937
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7937
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7938
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7938
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7939
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7939
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagau gaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7940
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7940
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau ugaaagccaa cgcaaucaca acaauacuaa ccgccguaac auuuugcuuc      240

gcgucaggcc aaaauauaac agaagaauuu uaccaaucaa caugcuccgc cguaucaaaa      300

ggauaccuag gugcauuacg aaccgguugg uacacaucag uaaucacaau agaacuuucc      360

aacauuaaag aaauaaaaug caauggcaca gacgcaaaag ucaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc cgucacagac uuacaacuau uaaugcaaag cacaccagca      480

acaggauccg gaucagcaau agcaucagga guagccgucu guaaaguacu acaccuagaa      540

ggcgaaguua auaaaauuaa aucagcuuua uuaucaacca acaaagcagu aguaucacua      600

uccggaugcg gagucuccgu ccuaacauuc aaaguacuag accucaagaa uuacauagau      660

aaacaacuac uaccaauacu caacaaacaa ucauguucaa uaccaaacau cgaaaccguc      720

auagaauuuc aacaaaaaaa uaauagacuc uuagaaauaa cacgagaauu uagcguaaac      780

gcaggaguca caaccccugu cucaacauac augcuaacca auuccgaauu auuaucacuc      840

auaaaugaca ugccaauaac uaaugaccaa aaaaaacuua ugucaaacaa cguacaaaua      900

guaagacaac aaucauauuc aauaaugugc auaaucaaag aagaaguuuu agcauaugua      960

guacaacuac cacuauaugg cgucauagac acaccaugcu ggaaauuaca cacaucaccu     1020

cuaugcacaa caaacacaaa agaaggaagc aacauuugcc uaaccagaac cgauagagga     1080

ugguacugcg auaacgcagg cucaguauca uucuucccuc aagccgaaac uugcaaaguc     1140

caaucaaaua gagucuucug cgauacaaug aacuccuuaa cuuuaccauc agaaguaaau     1200

cuaugcaacg uagauaucuu uaauccaaaa uacgauugca aaaucaugac aucaaaaaca     1260

gauguaucau cuaguguaau uaccucccua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucuaacaa augucgugga auaauaaaaa cauucucaaa cggaugcgau     1380

uauguaucaa auaaaggugu cgacaccgua ucaguaggca auacacuaua cuauguaaau     1440

aaacaagaag gacaaucacu cuacgucaaa ggugaaccaa uaauaaacuu cuacgaccca     1500

cuuguauucc caagcgacga auuugacgca ucaauaagcc aaguaaacga aaaaauaaac     1560

caaucacuag cauucaucag aaaaucagac gaacuacucc acaauguaaa ugcaggaaaa     1620

ucaacaacca auaucaugau aacaaccaua auaauaguca uaauaguaau acuauuaucc     1680

cucauagccg uuggacuacu ccuauauugu aaagcacgau aaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7941
<211>  1921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7941
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccaucacc accauacuca ccgcaguaac cuucugcuuc      240

gcauccggcc aaaacaucac agaagaguuc uaccagagua ccugcuccgc cgucuccaaa      300

ggcuaccuug gcgcccuccg uaccgggugg uacacauccg ucaucacaau cgaacucucc      360

aacaucaaag aaauaaagug caacggcaca gacgccaaag uaaaacugau aaagcaagaa      420

cucgacaaau acaaaaacgc cguaaccgac cuccagcuac uaaugcaauc cacucccgcc      480

accggcagcg gauccgccau cgccuccgga guagccgucu guaaagucuu acaccucgaa      540

ggcgaaguga acaaaaucaa auccgcccua cucucaacca acaaagccgu aguaucacuc      600

uccgggugcg gcguuucagu gcuaacguuc aaaguccuug accucaaaaa cuacaucgac      660

aaacaacucc uccccauccu aaauaaacaa uccugcucca uacccaacau cgagacuguc      720

aucgaguucc agcagaaaaa caaccgacuc cucgaaauca cacgcgaguu cucugucaac      780

gccggcguca caacccccgu cuccacauac augcucacca acagcgaacu ccucucccua      840

aucaaugaca ugcccaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      900

guccgccaac aauccuacag caucaugugc aucaucaaag aagaaguucu cgcauacgua      960

guacaacucc cccucuacgg agugaucgac acccccugcu ggaaacuaca caccagcccg     1020

cuuugcacca caaacaccaa ggaaggcucc aacaucugcc ucacucgaac cgaccgcggc     1080

ugguacugcg acaacgcagg cuccgucagu uucuuucccc aagcagaaac augcaaaguc     1140

caauccaacc gaguauucug cgacaccaug aacucccuca cccuaccauc cgaaguuaac     1200

cuaugcaacg uggacaucuu caaccccaag uacgacugca aaauuaugac cuccaaaacc     1260

gacguauccu ccagcgucau caccagccuc ggagcaauag ucuccugcua cggcaagacc     1320

aagugcaccg cuuccaacaa gugucgcgga aucaucaaaa ccuucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacaccgua uccguaggaa acacccuaua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca ucaucaauuu cuacgacccc     1500

cuagucuucc cuuccgacga guucgacgcg uccaucagcc aagucaauga aaagaucaac     1560

cagagccugg cauucauccg caaauccgac gaacuccucc acaacgucaa cgcgggaaaa     1620

uccacgacaa acaucaugau caccaccauc aucaucguca ucauagucau ucuccuuucu     1680

cucaucgccg ugggacuacu ucucuacugc aaagcccgau aaggacuagu cccuguuccc     1740

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1860

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1920

u                                                                     1921


<210>  7942
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7942
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7943
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7943
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccggug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7944
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7944
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7945
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7945
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7946
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7946
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7947
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7947
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaug aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7948
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7948
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu gaaagccaac gcaaucacaa caauacuaac cgccguaaca      180

uuuugcuucg cgucaggcca aaauauaaca gaagaauuuu accaaucaac augcuccgcc      240

guaucaaaag gauaccuagg ugcauuacga accgguuggu acacaucagu aaucacaaua      300

gaacuuucca acauuaaaga aauaaaaugc aauggcacag acgcaaaagu caaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgcc gucacagacu uacaacuauu aaugcaaagc      420

acaccagcaa caggauccgg aucagcaaua gcaucaggag uagccgucug uaaaguacua      480

caccuagaag gcgaaguuaa uaaaauuaaa ucagcuuuau uaucaaccaa caaagcagua      540

guaucacuau ccggaugcgg agucuccguc cuaacauuca aaguacuaga ccucaagaau      600

uacauagaua aacaacuacu accaauacuc aacaaacaau cauguucaau accaaacauc      660

gaaaccguca uagaauuuca acaaaaaaau aauagacucu uagaaauaac acgagaauuu      720

agcguaaacg caggagucac aaccccuguc ucaacauaca ugcuaaccaa uuccgaauua      780

uuaucacuca uaaaugacau gccaauaacu aaugaccaaa aaaaacuuau gucaaacaac      840

guacaaauag uaagacaaca aucauauuca auaaugugca uaaucaaaga agaaguuuua      900

gcauauguag uacaacuacc acuauauggc gucauagaca caccaugcug gaaauuacac      960

acaucaccuc uaugcacaac aaacacaaaa gaaggaagca acauuugccu aaccagaacc     1020

gauagaggau gguacugcga uaacgcaggc ucaguaucau ucuucccuca agccgaaacu     1080

ugcaaagucc aaucaaauag agucuucugc gauacaauga acuccuuaac uuuaccauca     1140

gaaguaaauc uaugcaacgu agauaucuuu aauccaaaau acgauugcaa aaucaugaca     1200

ucaaaaacag auguaucauc uaguguaauu accucccuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucuaacaaa ugucguggaa uaauaaaaac auucucaaac     1320

ggaugcgauu auguaucaaa uaaagguguc gacaccguau caguaggcaa uacacuauac     1380

uauguaaaua aacaagaagg acaaucacuc uacgucaaag gugaaccaau aauaaacuuc     1440

uacgacccac uuguauuccc aagcgacgaa uuugacgcau caauaagcca aguaaacgaa     1500

aaaauaaacc aaucacuagc auucaucaga aaaucagacg aacuacucca caauguaaau     1560

gcaggaaaau caacaaccaa uaucaugaua acaaccauaa uaauagucau aauaguaaua     1620

cuauuauccc ucauagccgu uggacuacuc cuauauugua aagcacgaua aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7949
<211>  1870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7949
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccaucacca ccauacucac cgcaguaacc      180

uucugcuucg cauccggcca aaacaucaca gaagaguucu accagaguac cugcuccgcc      240

gucuccaaag gcuaccuugg cgcccuccgu accggguggu acacauccgu caucacaauc      300

gaacucucca acaucaaaga aauaaagugc aacggcacag acgccaaagu aaaacugaua      360

aagcaagaac ucgacaaaua caaaaacgcc guaaccgacc uccagcuacu aaugcaaucc      420

acucccgcca ccggcagcgg auccgccauc gccuccggag uagccgucug uaaagucuua      480

caccucgaag gcgaagugaa caaaaucaaa uccgcccuac ucucaaccaa caaagccgua      540

guaucacucu ccgggugcgg cguuucagug cuaacguuca aaguccuuga ccucaaaaac      600

uacaucgaca aacaacuccu ccccauccua aauaaacaau ccugcuccau acccaacauc      660

gagacuguca ucgaguucca gcagaaaaac aaccgacucc ucgaaaucac acgcgaguuc      720

ucugucaacg ccggcgucac aacccccguc uccacauaca ugcucaccaa cagcgaacuc      780

cucucccuaa ucaaugacau gcccaucacc aacgaccaaa agaaacucau gucaaacaac      840

guccaaaucg uccgccaaca auccuacagc aucaugugca ucaucaaaga agaaguucuc      900

gcauacguag uacaacuccc ccucuacgga gugaucgaca cccccugcug gaaacuacac      960

accagcccgc uuugcaccac aaacaccaag gaaggcucca acaucugccu cacucgaacc     1020

gaccgcggcu gguacugcga caacgcaggc uccgucaguu ucuuucccca agcagaaaca     1080

ugcaaagucc aauccaaccg aguauucugc gacaccauga acucccucac ccuaccaucc     1140

gaaguuaacc uaugcaacgu ggacaucuuc aaccccaagu acgacugcaa aauuaugacc     1200

uccaaaaccg acguauccuc cagcgucauc accagccucg gagcaauagu cuccugcuac     1260

ggcaagacca agugcaccgc uuccaacaag ugucgcggaa ucaucaaaac cuucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacaccguau ccguaggaaa cacccuauac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau caucaauuuc     1440

uacgaccccc uagucuuccc uuccgacgag uucgacgcgu ccaucagcca agucaaugaa     1500

aagaucaacc agagccuggc auucauccgc aaauccgacg aacuccucca caacgucaac     1560

gcgggaaaau ccacgacaaa caucaugauc accaccauca ucaucgucau cauagucauu     1620

cuccuuucuc ucaucgccgu gggacuacuu cucuacugca aagcccgaua aggacuaguc     1680

ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau     1740

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1860

caccagaauu                                                            1870


<210>  7950
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7950
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7951
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7951
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccggugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7952
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7952
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7953
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7953
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7954
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7954
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7955
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7955
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaugagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7956
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7956
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauugaaa gccaacgcaa ucacaacaau acuaaccgcc      120

guaacauuuu gcuucgcguc aggccaaaau auaacagaag aauuuuacca aucaacaugc      180

uccgccguau caaaaggaua ccuaggugca uuacgaaccg guugguacac aucaguaauc      240

acaauagaac uuuccaacau uaaagaaaua aaaugcaaug gcacagacgc aaaagucaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgccguca cagacuuaca acuauuaaug      360

caaagcacac cagcaacagg auccggauca gcaauagcau caggaguagc cgucuguaaa      420

guacuacacc uagaaggcga aguuaauaaa auuaaaucag cuuuauuauc aaccaacaaa      480

gcaguaguau cacuauccgg augcggaguc uccguccuaa cauucaaagu acuagaccuc      540

aagaauuaca uagauaaaca acuacuacca auacucaaca aacaaucaug uucaauacca      600

aacaucgaaa ccgucauaga auuucaacaa aaaaauaaua gacucuuaga aauaacacga      660

gaauuuagcg uaaacgcagg agucacaacc ccugucucaa cauacaugcu aaccaauucc      720

gaauuauuau cacucauaaa ugacaugcca auaacuaaug accaaaaaaa acuuauguca      780

aacaacguac aaauaguaag acaacaauca uauucaauaa ugugcauaau caaagaagaa      840

guuuuagcau auguaguaca acuaccacua uauggcguca uagacacacc augcuggaaa      900

uuacacacau caccucuaug cacaacaaac acaaaagaag gaagcaacau uugccuaacc      960

agaaccgaua gaggauggua cugcgauaac gcaggcucag uaucauucuu cccucaagcc     1020

gaaacuugca aaguccaauc aaauagaguc uucugcgaua caaugaacuc cuuaacuuua     1080

ccaucagaag uaaaucuaug caacguagau aucuuuaauc caaaauacga uugcaaaauc     1140

augacaucaa aaacagaugu aucaucuagu guaauuaccu cccuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccucu aacaaauguc guggaauaau aaaaacauuc     1260

ucaaacggau gcgauuaugu aucaaauaaa ggugucgaca ccguaucagu aggcaauaca     1320

cuauacuaug uaaauaaaca agaaggacaa ucacucuacg ucaaagguga accaauaaua     1380

aacuucuacg acccacuugu auucccaagc gacgaauuug acgcaucaau aagccaagua     1440

aacgaaaaaa uaaaccaauc acuagcauuc aucagaaaau cagacgaacu acuccacaau     1500

guaaaugcag gaaaaucaac aaccaauauc augauaacaa ccauaauaau agucauaaua     1560

guaauacuau uaucccucau agccguugga cuacuccuau auuguaaagc acgauaagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7957
<211>  1816
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7957
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca ucaccaccau acucaccgca      120

guaaccuucu gcuucgcauc cggccaaaac aucacagaag aguucuacca gaguaccugc      180

uccgccgucu ccaaaggcua ccuuggcgcc cuccguaccg ggugguacac auccgucauc      240

acaaucgaac ucuccaacau caaagaaaua aagugcaacg gcacagacgc caaaguaaaa      300

cugauaaagc aagaacucga caaauacaaa aacgccguaa ccgaccucca gcuacuaaug      360

caauccacuc ccgccaccgg cagcggaucc gccaucgccu ccggaguagc cgucuguaaa      420

gucuuacacc ucgaaggcga agugaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gccguaguau cacucuccgg gugcggcguu ucagugcuaa cguucaaagu ccuugaccuc      540

aaaaacuaca ucgacaaaca acuccucccc auccuaaaua aacaauccug cuccauaccc      600

aacaucgaga cugucaucga guuccagcag aaaaacaacc gacuccucga aaucacacgc      660

gaguucucug ucaacgccgg cgucacaacc cccgucucca cauacaugcu caccaacagc      720

gaacuccucu cccuaaucaa ugacaugccc aucaccaacg accaaaagaa acucauguca      780

aacaacgucc aaaucguccg ccaacaaucc uacagcauca ugugcaucau caaagaagaa      840

guucucgcau acguaguaca acucccccuc uacggaguga ucgacacccc cugcuggaaa      900

cuacacacca gcccgcuuug caccacaaac accaaggaag gcuccaacau cugccucacu      960

cgaaccgacc gcggcuggua cugcgacaac gcaggcuccg ucaguuucuu uccccaagca     1020

gaaacaugca aaguccaauc caaccgagua uucugcgaca ccaugaacuc ccucacccua     1080

ccauccgaag uuaaccuaug caacguggac aucuucaacc ccaaguacga cugcaaaauu     1140

augaccucca aaaccgacgu auccuccagc gucaucacca gccucggagc aauagucucc     1200

ugcuacggca agaccaagug caccgcuucc aacaaguguc gcggaaucau caaaaccuuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca ccguauccgu aggaaacacc     1320

cuauacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccaucauc     1380

aauuucuacg acccccuagu cuucccuucc gacgaguucg acgcguccau cagccaaguc     1440

aaugaaaaga ucaaccagag ccuggcauuc auccgcaaau ccgacgaacu ccuccacaac     1500

gucaacgcgg gaaaauccac gacaaacauc augaucacca ccaucaucau cgucaucaua     1560

gucauucucc uuucucucau cgccguggga cuacuucucu acugcaaagc ccgauaagga     1620

cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu     1680

ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1800

cagagccacc agaauu                                                     1816


<210>  7958
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7958
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      540

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      600

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      660

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      780

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      840

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      900

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac     1020

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc     1080

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1140

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1200

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1380

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1500

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1560

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1680

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1740

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7959
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7959
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      360

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      480

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      540

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      600

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      660

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      720

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      780

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      840

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc     1080

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg     1140

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1380

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1440

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1500

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1620

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1680

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1740

agccugaucg ccgugggccu ccugcuguac ugcaaggccc ggugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7960
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7960
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      300

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      360

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      420

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      480

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      540

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      600

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      660

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      720

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      780

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      840

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      900

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      960

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac     1020

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc     1080

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1140

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1200

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1260

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1320

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1380

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1440

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1500

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1560

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1620

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1680

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1740

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7961
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7961
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      300

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      360

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      420

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      480

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      540

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      600

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      660

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      720

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      780

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      840

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      900

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      960

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau     1020

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu     1080

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu     1140

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1200

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1260

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1320

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1380

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1440

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1500

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1560

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1620

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1680

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1740

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7962
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7962
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      300

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      360

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      420

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      480

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      540

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      600

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      660

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      720

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      780

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      840

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      900

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      960

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac     1020

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc     1080

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1140

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1200

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1260

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1320

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1380

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1440

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1500

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1560

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1620

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1680

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1740

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7963
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7963
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      300

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      360

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      420

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      480

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      540

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      600

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      660

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      720

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      780

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      840

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      900

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      960

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau     1020

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc     1080

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc     1140

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1200

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1260

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1320

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1380

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1440

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1500

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1560

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1620

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1680

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1740

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaugaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7964
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7964
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuacuca uauugaaagc caacgcaauc acaacaauac uaaccgccgu aacauuuugc      300

uucgcgucag gccaaaauau aacagaagaa uuuuaccaau caacaugcuc cgccguauca      360

aaaggauacc uaggugcauu acgaaccggu ugguacacau caguaaucac aauagaacuu      420

uccaacauua aagaaauaaa augcaauggc acagacgcaa aagucaaacu aauaaaacaa      480

gaacuagaca aauauaaaaa cgccgucaca gacuuacaac uauuaaugca aagcacacca      540

gcaacaggau ccggaucagc aauagcauca ggaguagccg ucuguaaagu acuacaccua      600

gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa ccaacaaagc aguaguauca      660

cuauccggau gcggagucuc cguccuaaca uucaaaguac uagaccucaa gaauuacaua      720

gauaaacaac uacuaccaau acucaacaaa caaucauguu caauaccaaa caucgaaacc      780

gucauagaau uucaacaaaa aaauaauaga cucuuagaaa uaacacgaga auuuagcgua      840

aacgcaggag ucacaacccc ugucucaaca uacaugcuaa ccaauuccga auuauuauca      900

cucauaaaug acaugccaau aacuaaugac caaaaaaaac uuaugucaaa caacguacaa      960

auaguaagac aacaaucaua uucaauaaug ugcauaauca aagaagaagu uuuagcauau     1020

guaguacaac uaccacuaua uggcgucaua gacacaccau gcuggaaauu acacacauca     1080

ccucuaugca caacaaacac aaaagaagga agcaacauuu gccuaaccag aaccgauaga     1140

ggaugguacu gcgauaacgc aggcucagua ucauucuucc cucaagccga aacuugcaaa     1200

guccaaucaa auagagucuu cugcgauaca augaacuccu uaacuuuacc aucagaagua     1260

aaucuaugca acguagauau cuuuaaucca aaauacgauu gcaaaaucau gacaucaaaa     1320

acagauguau caucuagugu aauuaccucc cuaggagcaa uaguaagcug cuacggaaaa     1380

acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa aaacauucuc aaacggaugc     1440

gauuauguau caaauaaagg ugucgacacc guaucaguag gcaauacacu auacuaugua     1500

aauaaacaag aaggacaauc acucuacguc aaaggugaac caauaauaaa cuucuacgac     1560

ccacuuguau ucccaagcga cgaauuugac gcaucaauaa gccaaguaaa cgaaaaaaua     1620

aaccaaucac uagcauucau cagaaaauca gacgaacuac uccacaaugu aaaugcagga     1680

aaaucaacaa ccaauaucau gauaacaacc auaauaauag ucauaauagu aauacuauua     1740

ucccucauag ccguuggacu acuccuauau uguaaagcac gauaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7965
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7965
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaacuccuca uccucaaagc caacgccauc accaccauac ucaccgcagu aaccuucugc      300

uucgcauccg gccaaaacau cacagaagag uucuaccaga guaccugcuc cgccgucucc      360

aaaggcuacc uuggcgcccu ccguaccggg ugguacacau ccgucaucac aaucgaacuc      420

uccaacauca aagaaauaaa gugcaacggc acagacgcca aaguaaaacu gauaaagcaa      480

gaacucgaca aauacaaaaa cgccguaacc gaccuccagc uacuaaugca auccacuccc      540

gccaccggca gcggauccgc caucgccucc ggaguagccg ucuguaaagu cuuacaccuc      600

gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa ccaacaaagc cguaguauca      660

cucuccgggu gcggcguuuc agugcuaacg uucaaagucc uugaccucaa aaacuacauc      720

gacaaacaac uccuccccau ccuaaauaaa caauccugcu ccauacccaa caucgagacu      780

gucaucgagu uccagcagaa aaacaaccga cuccucgaaa ucacacgcga guucucuguc      840

aacgccggcg ucacaacccc cgucuccaca uacaugcuca ccaacagcga acuccucucc      900

cuaaucaaug acaugcccau caccaacgac caaaagaaac ucaugucaaa caacguccaa      960

aucguccgcc aacaauccua cagcaucaug ugcaucauca aagaagaagu ucucgcauac     1020

guaguacaac ucccccucua cggagugauc gacacccccu gcuggaaacu acacaccagc     1080

ccgcuuugca ccacaaacac caaggaaggc uccaacaucu gccucacucg aaccgaccgc     1140

ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc cccaagcaga aacaugcaaa     1200

guccaaucca accgaguauu cugcgacacc augaacuccc ucacccuacc auccgaaguu     1260

aaccuaugca acguggacau cuucaacccc aaguacgacu gcaaaauuau gaccuccaaa     1320

accgacguau ccuccagcgu caucaccagc cucggagcaa uagucuccug cuacggcaag     1380

accaagugca ccgcuuccaa caagugucgc ggaaucauca aaaccuucuc aaacggcugc     1440

gacuacgucu ccaacaaagg cgucgacacc guauccguag gaaacacccu auacuacguc     1500

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccaucaucaa uuucuacgac     1560

ccccuagucu ucccuuccga cgaguucgac gcguccauca gccaagucaa ugaaaagauc     1620

aaccagagcc uggcauucau ccgcaaaucc gacgaacucc uccacaacgu caacgcggga     1680

aaauccacga caaacaucau gaucaccacc aucaucaucg ucaucauagu cauucuccuu     1740

ucucucaucg ccgugggacu acuucucuac ugcaaagccc gauaaggacu aguguccacc     1800

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1860

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  7966
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7966
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7967
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7967
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      480

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1200

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1320

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccgugggccu ccugcuguac ugcaaggccc ggugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7968
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7968
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7969
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7969
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      480

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      540

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      600

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      660

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      720

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      780

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau      840

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      900

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu      960

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1020

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1080

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1140

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1200

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1260

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1320

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1380

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1440

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1500

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1560

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7970
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7970
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7971
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7971
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      480

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      540

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      600

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      660

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      720

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      780

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau      840

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc      900

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc      960

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1020

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1080

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1140

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1200

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1260

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1320

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1380

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1440

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1500

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1560

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaugaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7972
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7972
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuacuca uauugaaagc caacgcaauc acaacaauac uaaccgccgu aacauuuugc      120

uucgcgucag gccaaaauau aacagaagaa uuuuaccaau caacaugcuc cgccguauca      180

aaaggauacc uaggugcauu acgaaccggu ugguacacau caguaaucac aauagaacuu      240

uccaacauua aagaaauaaa augcaauggc acagacgcaa aagucaaacu aauaaaacaa      300

gaacuagaca aauauaaaaa cgccgucaca gacuuacaac uauuaaugca aagcacacca      360

gcaacaggau ccggaucagc aauagcauca ggaguagccg ucuguaaagu acuacaccua      420

gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa ccaacaaagc aguaguauca      480

cuauccggau gcggagucuc cguccuaaca uucaaaguac uagaccucaa gaauuacaua      540

gauaaacaac uacuaccaau acucaacaaa caaucauguu caauaccaaa caucgaaacc      600

gucauagaau uucaacaaaa aaauaauaga cucuuagaaa uaacacgaga auuuagcgua      660

aacgcaggag ucacaacccc ugucucaaca uacaugcuaa ccaauuccga auuauuauca      720

cucauaaaug acaugccaau aacuaaugac caaaaaaaac uuaugucaaa caacguacaa      780

auaguaagac aacaaucaua uucaauaaug ugcauaauca aagaagaagu uuuagcauau      840

guaguacaac uaccacuaua uggcgucaua gacacaccau gcuggaaauu acacacauca      900

ccucuaugca caacaaacac aaaagaagga agcaacauuu gccuaaccag aaccgauaga      960

ggaugguacu gcgauaacgc aggcucagua ucauucuucc cucaagccga aacuugcaaa     1020

guccaaucaa auagagucuu cugcgauaca augaacuccu uaacuuuacc aucagaagua     1080

aaucuaugca acguagauau cuuuaaucca aaauacgauu gcaaaaucau gacaucaaaa     1140

acagauguau caucuagugu aauuaccucc cuaggagcaa uaguaagcug cuacggaaaa     1200

acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa aaacauucuc aaacggaugc     1260

gauuauguau caaauaaagg ugucgacacc guaucaguag gcaauacacu auacuaugua     1320

aauaaacaag aaggacaauc acucuacguc aaaggugaac caauaauaaa cuucuacgac     1380

ccacuuguau ucccaagcga cgaauuugac gcaucaauaa gccaaguaaa cgaaaaaaua     1440

aaccaaucac uagcauucau cagaaaauca gacgaacuac uccacaaugu aaaugcagga     1500

aaaucaacaa ccaauaucau gauaacaacc auaauaauag ucauaauagu aauacuauua     1560

ucccucauag ccguuggacu acuccuauau uguaaagcac gauaaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7973
<211>  1817
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7973
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgccauc accaccauac ucaccgcagu aaccuucugc      120

uucgcauccg gccaaaacau cacagaagag uucuaccaga guaccugcuc cgccgucucc      180

aaaggcuacc uuggcgcccu ccguaccggg ugguacacau ccgucaucac aaucgaacuc      240

uccaacauca aagaaauaaa gugcaacggc acagacgcca aaguaaaacu gauaaagcaa      300

gaacucgaca aauacaaaaa cgccguaacc gaccuccagc uacuaaugca auccacuccc      360

gccaccggca gcggauccgc caucgccucc ggaguagccg ucuguaaagu cuuacaccuc      420

gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa ccaacaaagc cguaguauca      480

cucuccgggu gcggcguuuc agugcuaacg uucaaagucc uugaccucaa aaacuacauc      540

gacaaacaac uccuccccau ccuaaauaaa caauccugcu ccauacccaa caucgagacu      600

gucaucgagu uccagcagaa aaacaaccga cuccucgaaa ucacacgcga guucucuguc      660

aacgccggcg ucacaacccc cgucuccaca uacaugcuca ccaacagcga acuccucucc      720

cuaaucaaug acaugcccau caccaacgac caaaagaaac ucaugucaaa caacguccaa      780

aucguccgcc aacaauccua cagcaucaug ugcaucauca aagaagaagu ucucgcauac      840

guaguacaac ucccccucua cggagugauc gacacccccu gcuggaaacu acacaccagc      900

ccgcuuugca ccacaaacac caaggaaggc uccaacaucu gccucacucg aaccgaccgc      960

ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc cccaagcaga aacaugcaaa     1020

guccaaucca accgaguauu cugcgacacc augaacuccc ucacccuacc auccgaaguu     1080

aaccuaugca acguggacau cuucaacccc aaguacgacu gcaaaauuau gaccuccaaa     1140

accgacguau ccuccagcgu caucaccagc cucggagcaa uagucuccug cuacggcaag     1200

accaagugca ccgcuuccaa caagugucgc ggaaucauca aaaccuucuc aaacggcugc     1260

gacuacgucu ccaacaaagg cgucgacacc guauccguag gaaacacccu auacuacguc     1320

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccaucaucaa uuucuacgac     1380

ccccuagucu ucccuuccga cgaguucgac gcguccauca gccaagucaa ugaaaagauc     1440

aaccagagcc uggcauucau ccgcaaaucc gacgaacucc uccacaacgu caacgcggga     1500

aaauccacga caaacaucau gaucaccacc aucaucaucg ucaucauagu cauucuccuu     1560

ucucucaucg ccgugggacu acuucucuac ugcaaagccc gauaaggacu aguguccacc     1620

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1680

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1800

ucagagccac cagaauu                                                    1817


<210>  7974
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7974
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7975
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7975
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

ggugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7976
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7976
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7977
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7977
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7978
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7978
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7979
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7979
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7980
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7980
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauugaaagc caacgcaauc acaacaauac      120

uaaccgccgu aacauuuugc uucgcgucag gccaaaauau aacagaagaa uuuuaccaau      180

caacaugcuc cgccguauca aaaggauacc uaggugcauu acgaaccggu ugguacacau      240

caguaaucac aauagaacuu uccaacauua aagaaauaaa augcaauggc acagacgcaa      300

aagucaaacu aauaaaacaa gaacuagaca aauauaaaaa cgccgucaca gacuuacaac      360

uauuaaugca aagcacacca gcaacaggau ccggaucagc aauagcauca ggaguagccg      420

ucuguaaagu acuacaccua gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa      480

ccaacaaagc aguaguauca cuauccggau gcggagucuc cguccuaaca uucaaaguac      540

uagaccucaa gaauuacaua gauaaacaac uacuaccaau acucaacaaa caaucauguu      600

caauaccaaa caucgaaacc gucauagaau uucaacaaaa aaauaauaga cucuuagaaa      660

uaacacgaga auuuagcgua aacgcaggag ucacaacccc ugucucaaca uacaugcuaa      720

ccaauuccga auuauuauca cucauaaaug acaugccaau aacuaaugac caaaaaaaac      780

uuaugucaaa caacguacaa auaguaagac aacaaucaua uucaauaaug ugcauaauca      840

aagaagaagu uuuagcauau guaguacaac uaccacuaua uggcgucaua gacacaccau      900

gcuggaaauu acacacauca ccucuaugca caacaaacac aaaagaagga agcaacauuu      960

gccuaaccag aaccgauaga ggaugguacu gcgauaacgc aggcucagua ucauucuucc     1020

cucaagccga aacuugcaaa guccaaucaa auagagucuu cugcgauaca augaacuccu     1080

uaacuuuacc aucagaagua aaucuaugca acguagauau cuuuaaucca aaauacgauu     1140

gcaaaaucau gacaucaaaa acagauguau caucuagugu aauuaccucc cuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa     1260

aaacauucuc aaacggaugc gauuauguau caaauaaagg ugucgacacc guaucaguag     1320

gcaauacacu auacuaugua aauaaacaag aaggacaauc acucuacguc aaaggugaac     1380

caauaauaaa cuucuacgac ccacuuguau ucccaagcga cgaauuugac gcaucaauaa     1440

gccaaguaaa cgaaaaaaua aaccaaucac uagcauucau cagaaaauca gacgaacuac     1500

uccacaaugu aaaugcagga aaaucaacaa ccaauaucau gauaacaacc auaauaauag     1560

ucauaauagu aauacuauua ucccucauag ccguuggacu acuccuauau uguaaagcac     1620

gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7981
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7981
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccauc accaccauac      120

ucaccgcagu aaccuucugc uucgcauccg gccaaaacau cacagaagag uucuaccaga      180

guaccugcuc cgccgucucc aaaggcuacc uuggcgcccu ccguaccggg ugguacacau      240

ccgucaucac aaucgaacuc uccaacauca aagaaauaaa gugcaacggc acagacgcca      300

aaguaaaacu gauaaagcaa gaacucgaca aauacaaaaa cgccguaacc gaccuccagc      360

uacuaaugca auccacuccc gccaccggca gcggauccgc caucgccucc ggaguagccg      420

ucuguaaagu cuuacaccuc gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc cguaguauca cucuccgggu gcggcguuuc agugcuaacg uucaaagucc      540

uugaccucaa aaacuacauc gacaaacaac uccuccccau ccuaaauaaa caauccugcu      600

ccauacccaa caucgagacu gucaucgagu uccagcagaa aaacaaccga cuccucgaaa      660

ucacacgcga guucucuguc aacgccggcg ucacaacccc cgucuccaca uacaugcuca      720

ccaacagcga acuccucucc cuaaucaaug acaugcccau caccaacgac caaaagaaac      780

ucaugucaaa caacguccaa aucguccgcc aacaauccua cagcaucaug ugcaucauca      840

aagaagaagu ucucgcauac guaguacaac ucccccucua cggagugauc gacacccccu      900

gcuggaaacu acacaccagc ccgcuuugca ccacaaacac caaggaaggc uccaacaucu      960

gccucacucg aaccgaccgc ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc     1020

cccaagcaga aacaugcaaa guccaaucca accgaguauu cugcgacacc augaacuccc     1080

ucacccuacc auccgaaguu aaccuaugca acguggacau cuucaacccc aaguacgacu     1140

gcaaaauuau gaccuccaaa accgacguau ccuccagcgu caucaccagc cucggagcaa     1200

uagucuccug cuacggcaag accaagugca ccgcuuccaa caagugucgc ggaaucauca     1260

aaaccuucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacacc guauccguag     1320

gaaacacccu auacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccaucaucaa uuucuacgac ccccuagucu ucccuuccga cgaguucgac gcguccauca     1440

gccaagucaa ugaaaagauc aaccagagcc uggcauucau ccgcaaaucc gacgaacucc     1500

uccacaacgu caacgcggga aaauccacga caaacaucau gaucaccacc aucaucaucg     1560

ucaucauagu cauucuccuu ucucucaucg ccgugggacu acuucucuac ugcaaagccc     1620

gauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu uuuccugcca     1680

aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  7982
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7982
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7983
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7983
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

ggugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7984
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7984
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7985
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7985
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7986
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7986
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7987
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7987
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7988
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7988
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauugaaagc caacgcaauc acaacaauac      120

uaaccgccgu aacauuuugc uucgcgucag gccaaaauau aacagaagaa uuuuaccaau      180

caacaugcuc cgccguauca aaaggauacc uaggugcauu acgaaccggu ugguacacau      240

caguaaucac aauagaacuu uccaacauua aagaaauaaa augcaauggc acagacgcaa      300

aagucaaacu aauaaaacaa gaacuagaca aauauaaaaa cgccgucaca gacuuacaac      360

uauuaaugca aagcacacca gcaacaggau ccggaucagc aauagcauca ggaguagccg      420

ucuguaaagu acuacaccua gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa      480

ccaacaaagc aguaguauca cuauccggau gcggagucuc cguccuaaca uucaaaguac      540

uagaccucaa gaauuacaua gauaaacaac uacuaccaau acucaacaaa caaucauguu      600

caauaccaaa caucgaaacc gucauagaau uucaacaaaa aaauaauaga cucuuagaaa      660

uaacacgaga auuuagcgua aacgcaggag ucacaacccc ugucucaaca uacaugcuaa      720

ccaauuccga auuauuauca cucauaaaug acaugccaau aacuaaugac caaaaaaaac      780

uuaugucaaa caacguacaa auaguaagac aacaaucaua uucaauaaug ugcauaauca      840

aagaagaagu uuuagcauau guaguacaac uaccacuaua uggcgucaua gacacaccau      900

gcuggaaauu acacacauca ccucuaugca caacaaacac aaaagaagga agcaacauuu      960

gccuaaccag aaccgauaga ggaugguacu gcgauaacgc aggcucagua ucauucuucc     1020

cucaagccga aacuugcaaa guccaaucaa auagagucuu cugcgauaca augaacuccu     1080

uaacuuuacc aucagaagua aaucuaugca acguagauau cuuuaaucca aaauacgauu     1140

gcaaaaucau gacaucaaaa acagauguau caucuagugu aauuaccucc cuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa     1260

aaacauucuc aaacggaugc gauuauguau caaauaaagg ugucgacacc guaucaguag     1320

gcaauacacu auacuaugua aauaaacaag aaggacaauc acucuacguc aaaggugaac     1380

caauaauaaa cuucuacgac ccacuuguau ucccaagcga cgaauuugac gcaucaauaa     1440

gccaaguaaa cgaaaaaaua aaccaaucac uagcauucau cagaaaauca gacgaacuac     1500

uccacaaugu aaaugcagga aaaucaacaa ccaauaucau gauaacaacc auaauaauag     1560

ucauaauagu aauacuauua ucccucauag ccguuggacu acuccuauau uguaaagcac     1620

gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7989
<211>  1888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7989
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccauc accaccauac      120

ucaccgcagu aaccuucugc uucgcauccg gccaaaacau cacagaagag uucuaccaga      180

guaccugcuc cgccgucucc aaaggcuacc uuggcgcccu ccguaccggg ugguacacau      240

ccgucaucac aaucgaacuc uccaacauca aagaaauaaa gugcaacggc acagacgcca      300

aaguaaaacu gauaaagcaa gaacucgaca aauacaaaaa cgccguaacc gaccuccagc      360

uacuaaugca auccacuccc gccaccggca gcggauccgc caucgccucc ggaguagccg      420

ucuguaaagu cuuacaccuc gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc cguaguauca cucuccgggu gcggcguuuc agugcuaacg uucaaagucc      540

uugaccucaa aaacuacauc gacaaacaac uccuccccau ccuaaauaaa caauccugcu      600

ccauacccaa caucgagacu gucaucgagu uccagcagaa aaacaaccga cuccucgaaa      660

ucacacgcga guucucuguc aacgccggcg ucacaacccc cgucuccaca uacaugcuca      720

ccaacagcga acuccucucc cuaaucaaug acaugcccau caccaacgac caaaagaaac      780

ucaugucaaa caacguccaa aucguccgcc aacaauccua cagcaucaug ugcaucauca      840

aagaagaagu ucucgcauac guaguacaac ucccccucua cggagugauc gacacccccu      900

gcuggaaacu acacaccagc ccgcuuugca ccacaaacac caaggaaggc uccaacaucu      960

gccucacucg aaccgaccgc ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc     1020

cccaagcaga aacaugcaaa guccaaucca accgaguauu cugcgacacc augaacuccc     1080

ucacccuacc auccgaaguu aaccuaugca acguggacau cuucaacccc aaguacgacu     1140

gcaaaauuau gaccuccaaa accgacguau ccuccagcgu caucaccagc cucggagcaa     1200

uagucuccug cuacggcaag accaagugca ccgcuuccaa caagugucgc ggaaucauca     1260

aaaccuucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacacc guauccguag     1320

gaaacacccu auacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccaucaucaa uuucuacgac ccccuagucu ucccuuccga cgaguucgac gcguccauca     1440

gccaagucaa ugaaaagauc aaccagagcc uggcauucau ccgcaaaucc gacgaacucc     1500

uccacaacgu caacgcggga aaauccacga caaacaucau gaucaccacc aucaucaucg     1560

ucaucauagu cauucuccuu ucucucaucg ccgugggacu acuucucuac ugcaaagccc     1620

gauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu gaagagaucc     1680

uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau     1740

cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1860

aaaggcucuu uucagagcca ccagaauu                                        1888


<210>  7990
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7990
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7991
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7991
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccggug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7992
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  7992
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7993
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  7993
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7994
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  7994
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7995
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  7995
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaug aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7996
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  7996
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu gaaagccaac gcaaucacaa caauacuaac cgccguaaca      180

uuuugcuucg cgucaggcca aaauauaaca gaagaauuuu accaaucaac augcuccgcc      240

guaucaaaag gauaccuagg ugcauuacga accgguuggu acacaucagu aaucacaaua      300

gaacuuucca acauuaaaga aauaaaaugc aauggcacag acgcaaaagu caaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgcc gucacagacu uacaacuauu aaugcaaagc      420

acaccagcaa caggauccgg aucagcaaua gcaucaggag uagccgucug uaaaguacua      480

caccuagaag gcgaaguuaa uaaaauuaaa ucagcuuuau uaucaaccaa caaagcagua      540

guaucacuau ccggaugcgg agucuccguc cuaacauuca aaguacuaga ccucaagaau      600

uacauagaua aacaacuacu accaauacuc aacaaacaau cauguucaau accaaacauc      660

gaaaccguca uagaauuuca acaaaaaaau aauagacucu uagaaauaac acgagaauuu      720

agcguaaacg caggagucac aaccccuguc ucaacauaca ugcuaaccaa uuccgaauua      780

uuaucacuca uaaaugacau gccaauaacu aaugaccaaa aaaaacuuau gucaaacaac      840

guacaaauag uaagacaaca aucauauuca auaaugugca uaaucaaaga agaaguuuua      900

gcauauguag uacaacuacc acuauauggc gucauagaca caccaugcug gaaauuacac      960

acaucaccuc uaugcacaac aaacacaaaa gaaggaagca acauuugccu aaccagaacc     1020

gauagaggau gguacugcga uaacgcaggc ucaguaucau ucuucccuca agccgaaacu     1080

ugcaaagucc aaucaaauag agucuucugc gauacaauga acuccuuaac uuuaccauca     1140

gaaguaaauc uaugcaacgu agauaucuuu aauccaaaau acgauugcaa aaucaugaca     1200

ucaaaaacag auguaucauc uaguguaauu accucccuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucuaacaaa ugucguggaa uaauaaaaac auucucaaac     1320

ggaugcgauu auguaucaaa uaaagguguc gacaccguau caguaggcaa uacacuauac     1380

uauguaaaua aacaagaagg acaaucacuc uacgucaaag gugaaccaau aauaaacuuc     1440

uacgacccac uuguauuccc aagcgacgaa uuugacgcau caauaagcca aguaaacgaa     1500

aaaauaaacc aaucacuagc auucaucaga aaaucagacg aacuacucca caauguaaau     1560

gcaggaaaau caacaaccaa uaucaugaua acaaccauaa uaauagucau aauaguaaua     1620

cuauuauccc ucauagccgu uggacuacuc cuauauugua aagcacgaua aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7997
<211>  1950
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  7997
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccaucacca ccauacucac cgcaguaacc      180

uucugcuucg cauccggcca aaacaucaca gaagaguucu accagaguac cugcuccgcc      240

gucuccaaag gcuaccuugg cgcccuccgu accggguggu acacauccgu caucacaauc      300

gaacucucca acaucaaaga aauaaagugc aacggcacag acgccaaagu aaaacugaua      360

aagcaagaac ucgacaaaua caaaaacgcc guaaccgacc uccagcuacu aaugcaaucc      420

acucccgcca ccggcagcgg auccgccauc gccuccggag uagccgucug uaaagucuua      480

caccucgaag gcgaagugaa caaaaucaaa uccgcccuac ucucaaccaa caaagccgua      540

guaucacucu ccgggugcgg cguuucagug cuaacguuca aaguccuuga ccucaaaaac      600

uacaucgaca aacaacuccu ccccauccua aauaaacaau ccugcuccau acccaacauc      660

gagacuguca ucgaguucca gcagaaaaac aaccgacucc ucgaaaucac acgcgaguuc      720

ucugucaacg ccggcgucac aacccccguc uccacauaca ugcucaccaa cagcgaacuc      780

cucucccuaa ucaaugacau gcccaucacc aacgaccaaa agaaacucau gucaaacaac      840

guccaaaucg uccgccaaca auccuacagc aucaugugca ucaucaaaga agaaguucuc      900

gcauacguag uacaacuccc ccucuacgga gugaucgaca cccccugcug gaaacuacac      960

accagcccgc uuugcaccac aaacaccaag gaaggcucca acaucugccu cacucgaacc     1020

gaccgcggcu gguacugcga caacgcaggc uccgucaguu ucuuucccca agcagaaaca     1080

ugcaaagucc aauccaaccg aguauucugc gacaccauga acucccucac ccuaccaucc     1140

gaaguuaacc uaugcaacgu ggacaucuuc aaccccaagu acgacugcaa aauuaugacc     1200

uccaaaaccg acguauccuc cagcgucauc accagccucg gagcaauagu cuccugcuac     1260

ggcaagacca agugcaccgc uuccaacaag ugucgcggaa ucaucaaaac cuucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacaccguau ccguaggaaa cacccuauac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau caucaauuuc     1440

uacgaccccc uagucuuccc uuccgacgag uucgacgcgu ccaucagcca agucaaugaa     1500

aagaucaacc agagccuggc auucauccgc aaauccgacg aacuccucca caacgucaac     1560

gcgggaaaau ccacgacaaa caucaugauc accaccauca ucaucgucau cauagucauu     1620

cuccuuucuc ucaucgccgu gggacuacuu cucuacugca aagcccgaua aggacuagua     1680

cuggcugcau cucccuuucc ucuguccucc auccuucucc caggauggug aagggggacc     1740

ugguacccag ugauccccac cccaggaucc uaaaucauga cuuaccugcu aauaaaaacu     1800

cauuggaaaa gugagaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1920

ccaaaggcuc uuuucagagc caccagaauu                                      1950


<210>  7998
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7998
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  7999
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  7999
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  8000
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8000
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  8001
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8001
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cugaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  8002
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8002
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  8003
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8003
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag augaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  8004
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8004
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auugaaagcc      120

aacgcaauca caacaauacu aaccgccgua acauuuugcu ucgcgucagg ccaaaauaua      180

acagaagaau uuuaccaauc aacaugcucc gccguaucaa aaggauaccu aggugcauua      240

cgaaccgguu gguacacauc aguaaucaca auagaacuuu ccaacauuaa agaaauaaaa      300

ugcaauggca cagacgcaaa agucaaacua auaaaacaag aacuagacaa auauaaaaac      360

gccgucacag acuuacaacu auuaaugcaa agcacaccag caacaggauc cggaucagca      420

auagcaucag gaguagccgu cuguaaagua cuacaccuag aaggcgaagu uaauaaaauu      480

aaaucagcuu uauuaucaac caacaaagca guaguaucac uauccggaug cggagucucc      540

guccuaacau ucaaaguacu agaccucaag aauuacauag auaaacaacu acuaccaaua      600

cucaacaaac aaucauguuc aauaccaaac aucgaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac ucuuagaaau aacacgagaa uuuagcguaa acgcaggagu cacaaccccu      720

gucucaacau acaugcuaac caauuccgaa uuauuaucac ucauaaauga caugccaaua      780

acuaaugacc aaaaaaaacu uaugucaaac aacguacaaa uaguaagaca acaaucauau      840

ucaauaaugu gcauaaucaa agaagaaguu uuagcauaug uaguacaacu accacuauau      900

ggcgucauag acacaccaug cuggaaauua cacacaucac cucuaugcac aacaaacaca      960

aaagaaggaa gcaacauuug ccuaaccaga accgauagag gaugguacug cgauaacgca     1020

ggcucaguau cauucuuccc ucaagccgaa acuugcaaag uccaaucaaa uagagucuuc     1080

ugcgauacaa ugaacuccuu aacuuuacca ucagaaguaa aucuaugcaa cguagauauc     1140

uuuaauccaa aauacgauug caaaaucaug acaucaaaaa cagauguauc aucuagugua     1200

auuaccuccc uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucuaac     1260

aaaugucgug gaauaauaaa aacauucuca aacggaugcg auuauguauc aaauaaaggu     1320

gucgacaccg uaucaguagg caauacacua uacuauguaa auaaacaaga aggacaauca     1380

cucuacguca aaggugaacc aauaauaaac uucuacgacc cacuuguauu cccaagcgac     1440

gaauuugacg caucaauaag ccaaguaaac gaaaaaauaa accaaucacu agcauucauc     1500

agaaaaucag acgaacuacu ccacaaugua aaugcaggaa aaucaacaac caauaucaug     1560

auaacaacca uaauaauagu cauaauagua auacuauuau cccucauagc cguuggacua     1620

cuccuauauu guaaagcacg auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  8005
<211>  1856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8005
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauca ccaccauacu caccgcagua accuucugcu ucgcauccgg ccaaaacauc      180

acagaagagu ucuaccagag uaccugcucc gccgucucca aaggcuaccu uggcgcccuc      240

cguaccgggu gguacacauc cgucaucaca aucgaacucu ccaacaucaa agaaauaaag      300

ugcaacggca cagacgccaa aguaaaacug auaaagcaag aacucgacaa auacaaaaac      360

gccguaaccg accuccagcu acuaaugcaa uccacucccg ccaccggcag cggauccgcc      420

aucgccuccg gaguagccgu cuguaaaguc uuacaccucg aaggcgaagu gaacaaaauc      480

aaauccgccc uacucucaac caacaaagcc guaguaucac ucuccgggug cggcguuuca      540

gugcuaacgu ucaaaguccu ugaccucaaa aacuacaucg acaaacaacu ccuccccauc      600

cuaaauaaac aauccugcuc cauacccaac aucgagacug ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau cacacgcgag uucucuguca acgccggcgu cacaaccccc      720

gucuccacau acaugcucac caacagcgaa cuccucuccc uaaucaauga caugcccauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgcca acaauccuac      840

agcaucaugu gcaucaucaa agaagaaguu cucgcauacg uaguacaacu cccccucuac      900

ggagugaucg acacccccug cuggaaacua cacaccagcc cgcuuugcac cacaaacacc      960

aaggaaggcu ccaacaucug ccucacucga accgaccgcg gcugguacug cgacaacgca     1020

ggcuccguca guuucuuucc ccaagcagaa acaugcaaag uccaauccaa ccgaguauuc     1080

ugcgacacca ugaacucccu cacccuacca uccgaaguua accuaugcaa cguggacauc     1140

uucaacccca aguacgacug caaaauuaug accuccaaaa ccgacguauc cuccagcguc     1200

aucaccagcc ucggagcaau agucuccugc uacggcaaga ccaagugcac cgcuuccaac     1260

aagugucgcg gaaucaucaa aaccuucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacaccg uauccguagg aaacacccua uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc caucaucaau uucuacgacc cccuagucuu cccuuccgac     1440

gaguucgacg cguccaucag ccaagucaau gaaaagauca accagagccu ggcauucauc     1500

cgcaaauccg acgaacuccu ccacaacguc aacgcgggaa aauccacgac aaacaucaug     1560

aucaccacca ucaucaucgu caucauaguc auucuccuuu cucucaucgc cgugggacua     1620

cuucucuacu gcaaagcccg auaaggacua guguccaccu gucccuccug ggcugcugga     1680

uugucucguu uuccugccaa auaaacagga ucagcgcuuu acagaucuaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1800

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1856


<210>  8006
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8006
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8007
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8007
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccggug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8008
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8008
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8009
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8009
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8010
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8010
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8011
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8011
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaug aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8012
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8012
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu gaaagccaac gcaaucacaa caauacuaac cgccguaaca      180

uuuugcuucg cgucaggcca aaauauaaca gaagaauuuu accaaucaac augcuccgcc      240

guaucaaaag gauaccuagg ugcauuacga accgguuggu acacaucagu aaucacaaua      300

gaacuuucca acauuaaaga aauaaaaugc aauggcacag acgcaaaagu caaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgcc gucacagacu uacaacuauu aaugcaaagc      420

acaccagcaa caggauccgg aucagcaaua gcaucaggag uagccgucug uaaaguacua      480

caccuagaag gcgaaguuaa uaaaauuaaa ucagcuuuau uaucaaccaa caaagcagua      540

guaucacuau ccggaugcgg agucuccguc cuaacauuca aaguacuaga ccucaagaau      600

uacauagaua aacaacuacu accaauacuc aacaaacaau cauguucaau accaaacauc      660

gaaaccguca uagaauuuca acaaaaaaau aauagacucu uagaaauaac acgagaauuu      720

agcguaaacg caggagucac aaccccuguc ucaacauaca ugcuaaccaa uuccgaauua      780

uuaucacuca uaaaugacau gccaauaacu aaugaccaaa aaaaacuuau gucaaacaac      840

guacaaauag uaagacaaca aucauauuca auaaugugca uaaucaaaga agaaguuuua      900

gcauauguag uacaacuacc acuauauggc gucauagaca caccaugcug gaaauuacac      960

acaucaccuc uaugcacaac aaacacaaaa gaaggaagca acauuugccu aaccagaacc     1020

gauagaggau gguacugcga uaacgcaggc ucaguaucau ucuucccuca agccgaaacu     1080

ugcaaagucc aaucaaauag agucuucugc gauacaauga acuccuuaac uuuaccauca     1140

gaaguaaauc uaugcaacgu agauaucuuu aauccaaaau acgauugcaa aaucaugaca     1200

ucaaaaacag auguaucauc uaguguaauu accucccuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucuaacaaa ugucguggaa uaauaaaaac auucucaaac     1320

ggaugcgauu auguaucaaa uaaagguguc gacaccguau caguaggcaa uacacuauac     1380

uauguaaaua aacaagaagg acaaucacuc uacgucaaag gugaaccaau aauaaacuuc     1440

uacgacccac uuguauuccc aagcgacgaa uuugacgcau caauaagcca aguaaacgaa     1500

aaaauaaacc aaucacuagc auucaucaga aaaucagacg aacuacucca caauguaaau     1560

gcaggaaaau caacaaccaa uaucaugaua acaaccauaa uaauagucau aauaguaaua     1620

cuauuauccc ucauagccgu uggacuacuc cuauauugua aagcacgaua aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8013
<211>  1946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8013
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccaucacca ccauacucac cgcaguaacc      180

uucugcuucg cauccggcca aaacaucaca gaagaguucu accagaguac cugcuccgcc      240

gucuccaaag gcuaccuugg cgcccuccgu accggguggu acacauccgu caucacaauc      300

gaacucucca acaucaaaga aauaaagugc aacggcacag acgccaaagu aaaacugaua      360

aagcaagaac ucgacaaaua caaaaacgcc guaaccgacc uccagcuacu aaugcaaucc      420

acucccgcca ccggcagcgg auccgccauc gccuccggag uagccgucug uaaagucuua      480

caccucgaag gcgaagugaa caaaaucaaa uccgcccuac ucucaaccaa caaagccgua      540

guaucacucu ccgggugcgg cguuucagug cuaacguuca aaguccuuga ccucaaaaac      600

uacaucgaca aacaacuccu ccccauccua aauaaacaau ccugcuccau acccaacauc      660

gagacuguca ucgaguucca gcagaaaaac aaccgacucc ucgaaaucac acgcgaguuc      720

ucugucaacg ccggcgucac aacccccguc uccacauaca ugcucaccaa cagcgaacuc      780

cucucccuaa ucaaugacau gcccaucacc aacgaccaaa agaaacucau gucaaacaac      840

guccaaaucg uccgccaaca auccuacagc aucaugugca ucaucaaaga agaaguucuc      900

gcauacguag uacaacuccc ccucuacgga gugaucgaca cccccugcug gaaacuacac      960

accagcccgc uuugcaccac aaacaccaag gaaggcucca acaucugccu cacucgaacc     1020

gaccgcggcu gguacugcga caacgcaggc uccgucaguu ucuuucccca agcagaaaca     1080

ugcaaagucc aauccaaccg aguauucugc gacaccauga acucccucac ccuaccaucc     1140

gaaguuaacc uaugcaacgu ggacaucuuc aaccccaagu acgacugcaa aauuaugacc     1200

uccaaaaccg acguauccuc cagcgucauc accagccucg gagcaauagu cuccugcuac     1260

ggcaagacca agugcaccgc uuccaacaag ugucgcggaa ucaucaaaac cuucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacaccguau ccguaggaaa cacccuauac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau caucaauuuc     1440

uacgaccccc uagucuuccc uuccgacgag uucgacgcgu ccaucagcca agucaaugaa     1500

aagaucaacc agagccuggc auucauccgc aaauccgacg aacuccucca caacgucaac     1560

gcgggaaaau ccacgacaaa caucaugauc accaccauca ucaucgucau cauagucauu     1620

cuccuuucuc ucaucgccgu gggacuacuu cucuacugca aagcccgaua aggacuagug     1680

gaagcauuuu ccuggcugau uaaaagaaau uacucagcua uggucaucug uuccuguuag     1740

aaggcuaugc agcauauuau auacuaugcg cauguuauga aaugcauaau aaaaaauuuu     1800

aaaaaaucua aaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1920

aggcucuuuu cagagccacc agaauu                                          1946


<210>  8014
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8014
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8015
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8015
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8016
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8016
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8017
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8017
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cugaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8018
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8018
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8019
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8019
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag augaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8020
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8020
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auugaaagcc      120

aacgcaauca caacaauacu aaccgccgua acauuuugcu ucgcgucagg ccaaaauaua      180

acagaagaau uuuaccaauc aacaugcucc gccguaucaa aaggauaccu aggugcauua      240

cgaaccgguu gguacacauc aguaaucaca auagaacuuu ccaacauuaa agaaauaaaa      300

ugcaauggca cagacgcaaa agucaaacua auaaaacaag aacuagacaa auauaaaaac      360

gccgucacag acuuacaacu auuaaugcaa agcacaccag caacaggauc cggaucagca      420

auagcaucag gaguagccgu cuguaaagua cuacaccuag aaggcgaagu uaauaaaauu      480

aaaucagcuu uauuaucaac caacaaagca guaguaucac uauccggaug cggagucucc      540

guccuaacau ucaaaguacu agaccucaag aauuacauag auaaacaacu acuaccaaua      600

cucaacaaac aaucauguuc aauaccaaac aucgaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac ucuuagaaau aacacgagaa uuuagcguaa acgcaggagu cacaaccccu      720

gucucaacau acaugcuaac caauuccgaa uuauuaucac ucauaaauga caugccaaua      780

acuaaugacc aaaaaaaacu uaugucaaac aacguacaaa uaguaagaca acaaucauau      840

ucaauaaugu gcauaaucaa agaagaaguu uuagcauaug uaguacaacu accacuauau      900

ggcgucauag acacaccaug cuggaaauua cacacaucac cucuaugcac aacaaacaca      960

aaagaaggaa gcaacauuug ccuaaccaga accgauagag gaugguacug cgauaacgca     1020

ggcucaguau cauucuuccc ucaagccgaa acuugcaaag uccaaucaaa uagagucuuc     1080

ugcgauacaa ugaacuccuu aacuuuacca ucagaaguaa aucuaugcaa cguagauauc     1140

uuuaauccaa aauacgauug caaaaucaug acaucaaaaa cagauguauc aucuagugua     1200

auuaccuccc uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucuaac     1260

aaaugucgug gaauaauaaa aacauucuca aacggaugcg auuauguauc aaauaaaggu     1320

gucgacaccg uaucaguagg caauacacua uacuauguaa auaaacaaga aggacaauca     1380

cucuacguca aaggugaacc aauaauaaac uucuacgacc cacuuguauu cccaagcgac     1440

gaauuugacg caucaauaag ccaaguaaac gaaaaaauaa accaaucacu agcauucauc     1500

agaaaaucag acgaacuacu ccacaaugua aaugcaggaa aaucaacaac caauaucaug     1560

auaacaacca uaauaauagu cauaauagua auacuauuau cccucauagc cguuggacua     1620

cuccuauauu guaaagcacg auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8021
<211>  1923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8021
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauca ccaccauacu caccgcagua accuucugcu ucgcauccgg ccaaaacauc      180

acagaagagu ucuaccagag uaccugcucc gccgucucca aaggcuaccu uggcgcccuc      240

cguaccgggu gguacacauc cgucaucaca aucgaacucu ccaacaucaa agaaauaaag      300

ugcaacggca cagacgccaa aguaaaacug auaaagcaag aacucgacaa auacaaaaac      360

gccguaaccg accuccagcu acuaaugcaa uccacucccg ccaccggcag cggauccgcc      420

aucgccuccg gaguagccgu cuguaaaguc uuacaccucg aaggcgaagu gaacaaaauc      480

aaauccgccc uacucucaac caacaaagcc guaguaucac ucuccgggug cggcguuuca      540

gugcuaacgu ucaaaguccu ugaccucaaa aacuacaucg acaaacaacu ccuccccauc      600

cuaaauaaac aauccugcuc cauacccaac aucgagacug ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau cacacgcgag uucucuguca acgccggcgu cacaaccccc      720

gucuccacau acaugcucac caacagcgaa cuccucuccc uaaucaauga caugcccauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgcca acaauccuac      840

agcaucaugu gcaucaucaa agaagaaguu cucgcauacg uaguacaacu cccccucuac      900

ggagugaucg acacccccug cuggaaacua cacaccagcc cgcuuugcac cacaaacacc      960

aaggaaggcu ccaacaucug ccucacucga accgaccgcg gcugguacug cgacaacgca     1020

ggcuccguca guuucuuucc ccaagcagaa acaugcaaag uccaauccaa ccgaguauuc     1080

ugcgacacca ugaacucccu cacccuacca uccgaaguua accuaugcaa cguggacauc     1140

uucaacccca aguacgacug caaaauuaug accuccaaaa ccgacguauc cuccagcguc     1200

aucaccagcc ucggagcaau agucuccugc uacggcaaga ccaagugcac cgcuuccaac     1260

aagugucgcg gaaucaucaa aaccuucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacaccg uauccguagg aaacacccua uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc caucaucaau uucuacgacc cccuagucuu cccuuccgac     1440

gaguucgacg cguccaucag ccaagucaau gaaaagauca accagagccu ggcauucauc     1500

cgcaaauccg acgaacuccu ccacaacguc aacgcgggaa aauccacgac aaacaucaug     1560

aucaccacca ucaucaucgu caucauaguc auucuccuuu cucucaucgc cgugggacua     1620

cuucucuacu gcaaagcccg auaaggacua guacuggcug caucucccuu uccucugucc     1680

uccauccuuc ucccaggaug gugaaggggg accugguacc cagugauccc caccccagga     1740

uccuaaauca ugacuuaccu gcuaauaaaa acucauugga aaagugagaa gaucuaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1860

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1920

auu                                                                   1923


<210>  8022
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8022
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8023
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8023
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8024
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8024
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8025
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8025
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cugaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8026
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8026
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8027
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8027
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag augaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8028
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8028
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auugaaagcc      120

aacgcaauca caacaauacu aaccgccgua acauuuugcu ucgcgucagg ccaaaauaua      180

acagaagaau uuuaccaauc aacaugcucc gccguaucaa aaggauaccu aggugcauua      240

cgaaccgguu gguacacauc aguaaucaca auagaacuuu ccaacauuaa agaaauaaaa      300

ugcaauggca cagacgcaaa agucaaacua auaaaacaag aacuagacaa auauaaaaac      360

gccgucacag acuuacaacu auuaaugcaa agcacaccag caacaggauc cggaucagca      420

auagcaucag gaguagccgu cuguaaagua cuacaccuag aaggcgaagu uaauaaaauu      480

aaaucagcuu uauuaucaac caacaaagca guaguaucac uauccggaug cggagucucc      540

guccuaacau ucaaaguacu agaccucaag aauuacauag auaaacaacu acuaccaaua      600

cucaacaaac aaucauguuc aauaccaaac aucgaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac ucuuagaaau aacacgagaa uuuagcguaa acgcaggagu cacaaccccu      720

gucucaacau acaugcuaac caauuccgaa uuauuaucac ucauaaauga caugccaaua      780

acuaaugacc aaaaaaaacu uaugucaaac aacguacaaa uaguaagaca acaaucauau      840

ucaauaaugu gcauaaucaa agaagaaguu uuagcauaug uaguacaacu accacuauau      900

ggcgucauag acacaccaug cuggaaauua cacacaucac cucuaugcac aacaaacaca      960

aaagaaggaa gcaacauuug ccuaaccaga accgauagag gaugguacug cgauaacgca     1020

ggcucaguau cauucuuccc ucaagccgaa acuugcaaag uccaaucaaa uagagucuuc     1080

ugcgauacaa ugaacuccuu aacuuuacca ucagaaguaa aucuaugcaa cguagauauc     1140

uuuaauccaa aauacgauug caaaaucaug acaucaaaaa cagauguauc aucuagugua     1200

auuaccuccc uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucuaac     1260

aaaugucgug gaauaauaaa aacauucuca aacggaugcg auuauguauc aaauaaaggu     1320

gucgacaccg uaucaguagg caauacacua uacuauguaa auaaacaaga aggacaauca     1380

cucuacguca aaggugaacc aauaauaaac uucuacgacc cacuuguauu cccaagcgac     1440

gaauuugacg caucaauaag ccaaguaaac gaaaaaauaa accaaucacu agcauucauc     1500

agaaaaucag acgaacuacu ccacaaugua aaugcaggaa aaucaacaac caauaucaug     1560

auaacaacca uaauaauagu cauaauagua auacuauuau cccucauagc cguuggacua     1620

cuccuauauu guaaagcacg auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8029
<211>  1919
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8029
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauca ccaccauacu caccgcagua accuucugcu ucgcauccgg ccaaaacauc      180

acagaagagu ucuaccagag uaccugcucc gccgucucca aaggcuaccu uggcgcccuc      240

cguaccgggu gguacacauc cgucaucaca aucgaacucu ccaacaucaa agaaauaaag      300

ugcaacggca cagacgccaa aguaaaacug auaaagcaag aacucgacaa auacaaaaac      360

gccguaaccg accuccagcu acuaaugcaa uccacucccg ccaccggcag cggauccgcc      420

aucgccuccg gaguagccgu cuguaaaguc uuacaccucg aaggcgaagu gaacaaaauc      480

aaauccgccc uacucucaac caacaaagcc guaguaucac ucuccgggug cggcguuuca      540

gugcuaacgu ucaaaguccu ugaccucaaa aacuacaucg acaaacaacu ccuccccauc      600

cuaaauaaac aauccugcuc cauacccaac aucgagacug ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau cacacgcgag uucucuguca acgccggcgu cacaaccccc      720

gucuccacau acaugcucac caacagcgaa cuccucuccc uaaucaauga caugcccauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgcca acaauccuac      840

agcaucaugu gcaucaucaa agaagaaguu cucgcauacg uaguacaacu cccccucuac      900

ggagugaucg acacccccug cuggaaacua cacaccagcc cgcuuugcac cacaaacacc      960

aaggaaggcu ccaacaucug ccucacucga accgaccgcg gcugguacug cgacaacgca     1020

ggcuccguca guuucuuucc ccaagcagaa acaugcaaag uccaauccaa ccgaguauuc     1080

ugcgacacca ugaacucccu cacccuacca uccgaaguua accuaugcaa cguggacauc     1140

uucaacccca aguacgacug caaaauuaug accuccaaaa ccgacguauc cuccagcguc     1200

aucaccagcc ucggagcaau agucuccugc uacggcaaga ccaagugcac cgcuuccaac     1260

aagugucgcg gaaucaucaa aaccuucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacaccg uauccguagg aaacacccua uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc caucaucaau uucuacgacc cccuagucuu cccuuccgac     1440

gaguucgacg cguccaucag ccaagucaau gaaaagauca accagagccu ggcauucauc     1500

cgcaaauccg acgaacuccu ccacaacguc aacgcgggaa aauccacgac aaacaucaug     1560

aucaccacca ucaucaucgu caucauaguc auucuccuuu cucucaucgc cgugggacua     1620

cuucucuacu gcaaagcccg auaaggacua guggaagcau uuuccuggcu gauuaaaaga     1680

aauuacucag cuauggucau cuguuccugu uagaaggcua ugcagcauau uauauacuau     1740

gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau cuaaaagauc uaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1860

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1919


<210>  8030
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8030
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8031
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8031
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8032
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8032
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8033
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8033
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8034
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8034
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8035
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8035
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8036
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8036
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauugaa agccaacgca      120

aucacaacaa uacuaaccgc cguaacauuu ugcuucgcgu caggccaaaa uauaacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucaaaaggau accuaggugc auuacgaacc      240

gguugguaca caucaguaau cacaauagaa cuuuccaaca uuaaagaaau aaaaugcaau      300

ggcacagacg caaaagucaa acuaauaaaa caagaacuag acaaauauaa aaacgccguc      360

acagacuuac aacuauuaau gcaaagcaca ccagcaacag gauccggauc agcaauagca      420

ucaggaguag ccgucuguaa aguacuacac cuagaaggcg aaguuaauaa aauuaaauca      480

gcuuuauuau caaccaacaa agcaguagua ucacuauccg gaugcggagu cuccguccua      540

acauucaaag uacuagaccu caagaauuac auagauaaac aacuacuacc aauacucaac      600

aaacaaucau guucaauacc aaacaucgaa accgucauag aauuucaaca aaaaaauaau      660

agacucuuag aaauaacacg agaauuuagc guaaacgcag gagucacaac cccugucuca      720

acauacaugc uaaccaauuc cgaauuauua ucacucauaa augacaugcc aauaacuaau      780

gaccaaaaaa aacuuauguc aaacaacgua caaauaguaa gacaacaauc auauucaaua      840

augugcauaa ucaaagaaga aguuuuagca uauguaguac aacuaccacu auauggcguc      900

auagacacac caugcuggaa auuacacaca ucaccucuau gcacaacaaa cacaaaagaa      960

ggaagcaaca uuugccuaac cagaaccgau agaggauggu acugcgauaa cgcaggcuca     1020

guaucauucu ucccucaagc cgaaacuugc aaaguccaau caaauagagu cuucugcgau     1080

acaaugaacu ccuuaacuuu accaucagaa guaaaucuau gcaacguaga uaucuuuaau     1140

ccaaaauacg auugcaaaau caugacauca aaaacagaug uaucaucuag uguaauuacc     1200

ucccuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc uaacaaaugu     1260

cguggaauaa uaaaaacauu cucaaacgga ugcgauuaug uaucaaauaa aggugucgac     1320

accguaucag uaggcaauac acuauacuau guaaauaaac aagaaggaca aucacucuac     1380

gucaaaggug aaccaauaau aaacuucuac gacccacuug uauucccaag cgacgaauuu     1440

gacgcaucaa uaagccaagu aaacgaaaaa auaaaccaau cacuagcauu caucagaaaa     1500

ucagacgaac uacuccacaa uguaaaugca ggaaaaucaa caaccaauau caugauaaca     1560

accauaauaa uagucauaau aguaauacua uuaucccuca uagccguugg acuacuccua     1620

uauuguaaag cacgauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8037
<211>  1837
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8037
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

aucaccacca uacucaccgc aguaaccuuc ugcuucgcau ccggccaaaa caucacagaa      180

gaguucuacc agaguaccug cuccgccguc uccaaaggcu accuuggcgc ccuccguacc      240

gggugguaca cauccgucau cacaaucgaa cucuccaaca ucaaagaaau aaagugcaac      300

ggcacagacg ccaaaguaaa acugauaaag caagaacucg acaaauacaa aaacgccgua      360

accgaccucc agcuacuaau gcaauccacu cccgccaccg gcagcggauc cgccaucgcc      420

uccggaguag ccgucuguaa agucuuacac cucgaaggcg aagugaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agccguagua ucacucuccg ggugcggcgu uucagugcua      540

acguucaaag uccuugaccu caaaaacuac aucgacaaac aacuccuccc cauccuaaau      600

aaacaauccu gcuccauacc caacaucgag acugucaucg aguuccagca gaaaaacaac      660

cgacuccucg aaaucacacg cgaguucucu gucaacgccg gcgucacaac ccccgucucc      720

acauacaugc ucaccaacag cgaacuccuc ucccuaauca augacaugcc caucaccaac      780

gaccaaaaga aacucauguc aaacaacguc caaaucgucc gccaacaauc cuacagcauc      840

augugcauca ucaaagaaga aguucucgca uacguaguac aacucccccu cuacggagug      900

aucgacaccc ccugcuggaa acuacacacc agcccgcuuu gcaccacaaa caccaaggaa      960

ggcuccaaca ucugccucac ucgaaccgac cgcggcuggu acugcgacaa cgcaggcucc     1020

gucaguuucu uuccccaagc agaaacaugc aaaguccaau ccaaccgagu auucugcgac     1080

accaugaacu cccucacccu accauccgaa guuaaccuau gcaacgugga caucuucaac     1140

cccaaguacg acugcaaaau uaugaccucc aaaaccgacg uauccuccag cgucaucacc     1200

agccucggag caauagucuc cugcuacggc aagaccaagu gcaccgcuuc caacaagugu     1260

cgcggaauca ucaaaaccuu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

accguauccg uaggaaacac ccuauacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccaucau caauuucuac gacccccuag ucuucccuuc cgacgaguuc     1440

gacgcgucca ucagccaagu caaugaaaag aucaaccaga gccuggcauu cauccgcaaa     1500

uccgacgaac uccuccacaa cgucaacgcg ggaaaaucca cgacaaacau caugaucacc     1560

accaucauca ucgucaucau agucauucuc cuuucucuca ucgccguggg acuacuucuc     1620

uacugcaaag cccgauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu     1680

ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1800

ccccccccca aaggcucuuu ucagagccac cagaauu                              1837


<210>  8038
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8038
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8039
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8039
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccggugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8040
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8040
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8041
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8041
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8042
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8042
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8043
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8043
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaugagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8044
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8044
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauugaaa      120

gccaacgcaa ucacaacaau acuaaccgcc guaacauuuu gcuucgcguc aggccaaaau      180

auaacagaag aauuuuacca aucaacaugc uccgccguau caaaaggaua ccuaggugca      240

uuacgaaccg guugguacac aucaguaauc acaauagaac uuuccaacau uaaagaaaua      300

aaaugcaaug gcacagacgc aaaagucaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgccguca cagacuuaca acuauuaaug caaagcacac cagcaacagg auccggauca      420

gcaauagcau caggaguagc cgucuguaaa guacuacacc uagaaggcga aguuaauaaa      480

auuaaaucag cuuuauuauc aaccaacaaa gcaguaguau cacuauccgg augcggaguc      540

uccguccuaa cauucaaagu acuagaccuc aagaauuaca uagauaaaca acuacuacca      600

auacucaaca aacaaucaug uucaauacca aacaucgaaa ccgucauaga auuucaacaa      660

aaaaauaaua gacucuuaga aauaacacga gaauuuagcg uaaacgcagg agucacaacc      720

ccugucucaa cauacaugcu aaccaauucc gaauuauuau cacucauaaa ugacaugcca      780

auaacuaaug accaaaaaaa acuuauguca aacaacguac aaauaguaag acaacaauca      840

uauucaauaa ugugcauaau caaagaagaa guuuuagcau auguaguaca acuaccacua      900

uauggcguca uagacacacc augcuggaaa uuacacacau caccucuaug cacaacaaac      960

acaaaagaag gaagcaacau uugccuaacc agaaccgaua gaggauggua cugcgauaac     1020

gcaggcucag uaucauucuu cccucaagcc gaaacuugca aaguccaauc aaauagaguc     1080

uucugcgaua caaugaacuc cuuaacuuua ccaucagaag uaaaucuaug caacguagau     1140

aucuuuaauc caaaauacga uugcaaaauc augacaucaa aaacagaugu aucaucuagu     1200

guaauuaccu cccuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccucu     1260

aacaaauguc guggaauaau aaaaacauuc ucaaacggau gcgauuaugu aucaaauaaa     1320

ggugucgaca ccguaucagu aggcaauaca cuauacuaug uaaauaaaca agaaggacaa     1380

ucacucuacg ucaaagguga accaauaaua aacuucuacg acccacuugu auucccaagc     1440

gacgaauuug acgcaucaau aagccaagua aacgaaaaaa uaaaccaauc acuagcauuc     1500

aucagaaaau cagacgaacu acuccacaau guaaaugcag gaaaaucaac aaccaauauc     1560

augauaacaa ccauaauaau agucauaaua guaauacuau uaucccucau agccguugga     1620

cuacuccuau auuguaaagc acgauaagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8045
<211>  1846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8045
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca ucaccaccau acucaccgca guaaccuucu gcuucgcauc cggccaaaac      180

aucacagaag aguucuacca gaguaccugc uccgccgucu ccaaaggcua ccuuggcgcc      240

cuccguaccg ggugguacac auccgucauc acaaucgaac ucuccaacau caaagaaaua      300

aagugcaacg gcacagacgc caaaguaaaa cugauaaagc aagaacucga caaauacaaa      360

aacgccguaa ccgaccucca gcuacuaaug caauccacuc ccgccaccgg cagcggaucc      420

gccaucgccu ccggaguagc cgucuguaaa gucuuacacc ucgaaggcga agugaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gccguaguau cacucuccgg gugcggcguu      540

ucagugcuaa cguucaaagu ccuugaccuc aaaaacuaca ucgacaaaca acuccucccc      600

auccuaaaua aacaauccug cuccauaccc aacaucgaga cugucaucga guuccagcag      660

aaaaacaacc gacuccucga aaucacacgc gaguucucug ucaacgccgg cgucacaacc      720

cccgucucca cauacaugcu caccaacagc gaacuccucu cccuaaucaa ugacaugccc      780

aucaccaacg accaaaagaa acucauguca aacaacgucc aaaucguccg ccaacaaucc      840

uacagcauca ugugcaucau caaagaagaa guucucgcau acguaguaca acucccccuc      900

uacggaguga ucgacacccc cugcuggaaa cuacacacca gcccgcuuug caccacaaac      960

accaaggaag gcuccaacau cugccucacu cgaaccgacc gcggcuggua cugcgacaac     1020

gcaggcuccg ucaguuucuu uccccaagca gaaacaugca aaguccaauc caaccgagua     1080

uucugcgaca ccaugaacuc ccucacccua ccauccgaag uuaaccuaug caacguggac     1140

aucuucaacc ccaaguacga cugcaaaauu augaccucca aaaccgacgu auccuccagc     1200

gucaucacca gccucggagc aauagucucc ugcuacggca agaccaagug caccgcuucc     1260

aacaaguguc gcggaaucau caaaaccuuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca ccguauccgu aggaaacacc cuauacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccaucauc aauuucuacg acccccuagu cuucccuucc     1440

gacgaguucg acgcguccau cagccaaguc aaugaaaaga ucaaccagag ccuggcauuc     1500

auccgcaaau ccgacgaacu ccuccacaac gucaacgcgg gaaaauccac gacaaacauc     1560

augaucacca ccaucaucau cgucaucaua gucauucucc uuucucucau cgccguggga     1620

cuacuucucu acugcaaagc ccgauaagga cuagucccug uucccagagc ccacuuuuuu     1680

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1800

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1846


<210>  8046
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8046
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8047
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8047
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccggugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8048
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8048
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8049
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8049
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8050
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8050
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8051
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8051
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaugagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8052
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8052
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauugaa agccaacgca      120

aucacaacaa uacuaaccgc cguaacauuu ugcuucgcgu caggccaaaa uauaacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucaaaaggau accuaggugc auuacgaacc      240

gguugguaca caucaguaau cacaauagaa cuuuccaaca uuaaagaaau aaaaugcaau      300

ggcacagacg caaaagucaa acuaauaaaa caagaacuag acaaauauaa aaacgccguc      360

acagacuuac aacuauuaau gcaaagcaca ccagcaacag gauccggauc agcaauagca      420

ucaggaguag ccgucuguaa aguacuacac cuagaaggcg aaguuaauaa aauuaaauca      480

gcuuuauuau caaccaacaa agcaguagua ucacuauccg gaugcggagu cuccguccua      540

acauucaaag uacuagaccu caagaauuac auagauaaac aacuacuacc aauacucaac      600

aaacaaucau guucaauacc aaacaucgaa accgucauag aauuucaaca aaaaaauaau      660

agacucuuag aaauaacacg agaauuuagc guaaacgcag gagucacaac cccugucuca      720

acauacaugc uaaccaauuc cgaauuauua ucacucauaa augacaugcc aauaacuaau      780

gaccaaaaaa aacuuauguc aaacaacgua caaauaguaa gacaacaauc auauucaaua      840

augugcauaa ucaaagaaga aguuuuagca uauguaguac aacuaccacu auauggcguc      900

auagacacac caugcuggaa auuacacaca ucaccucuau gcacaacaaa cacaaaagaa      960

ggaagcaaca uuugccuaac cagaaccgau agaggauggu acugcgauaa cgcaggcuca     1020

guaucauucu ucccucaagc cgaaacuugc aaaguccaau caaauagagu cuucugcgau     1080

acaaugaacu ccuuaacuuu accaucagaa guaaaucuau gcaacguaga uaucuuuaau     1140

ccaaaauacg auugcaaaau caugacauca aaaacagaug uaucaucuag uguaauuacc     1200

ucccuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc uaacaaaugu     1260

cguggaauaa uaaaaacauu cucaaacgga ugcgauuaug uaucaaauaa aggugucgac     1320

accguaucag uaggcaauac acuauacuau guaaauaaac aagaaggaca aucacucuac     1380

gucaaaggug aaccaauaau aaacuucuac gacccacuug uauucccaag cgacgaauuu     1440

gacgcaucaa uaagccaagu aaacgaaaaa auaaaccaau cacuagcauu caucagaaaa     1500

ucagacgaac uacuccacaa uguaaaugca ggaaaaucaa caaccaauau caugauaaca     1560

accauaauaa uagucauaau aguaauacua uuaucccuca uagccguugg acuacuccua     1620

uauuguaaag cacgauaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8053
<211>  1901
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8053
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

aucaccacca uacucaccgc aguaaccuuc ugcuucgcau ccggccaaaa caucacagaa      180

gaguucuacc agaguaccug cuccgccguc uccaaaggcu accuuggcgc ccuccguacc      240

gggugguaca cauccgucau cacaaucgaa cucuccaaca ucaaagaaau aaagugcaac      300

ggcacagacg ccaaaguaaa acugauaaag caagaacucg acaaauacaa aaacgccgua      360

accgaccucc agcuacuaau gcaauccacu cccgccaccg gcagcggauc cgccaucgcc      420

uccggaguag ccgucuguaa agucuuacac cucgaaggcg aagugaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agccguagua ucacucuccg ggugcggcgu uucagugcua      540

acguucaaag uccuugaccu caaaaacuac aucgacaaac aacuccuccc cauccuaaau      600

aaacaauccu gcuccauacc caacaucgag acugucaucg aguuccagca gaaaaacaac      660

cgacuccucg aaaucacacg cgaguucucu gucaacgccg gcgucacaac ccccgucucc      720

acauacaugc ucaccaacag cgaacuccuc ucccuaauca augacaugcc caucaccaac      780

gaccaaaaga aacucauguc aaacaacguc caaaucgucc gccaacaauc cuacagcauc      840

augugcauca ucaaagaaga aguucucgca uacguaguac aacucccccu cuacggagug      900

aucgacaccc ccugcuggaa acuacacacc agcccgcuuu gcaccacaaa caccaaggaa      960

ggcuccaaca ucugccucac ucgaaccgac cgcggcuggu acugcgacaa cgcaggcucc     1020

gucaguuucu uuccccaagc agaaacaugc aaaguccaau ccaaccgagu auucugcgac     1080

accaugaacu cccucacccu accauccgaa guuaaccuau gcaacgugga caucuucaac     1140

cccaaguacg acugcaaaau uaugaccucc aaaaccgacg uauccuccag cgucaucacc     1200

agccucggag caauagucuc cugcuacggc aagaccaagu gcaccgcuuc caacaagugu     1260

cgcggaauca ucaaaaccuu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

accguauccg uaggaaacac ccuauacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccaucau caauuucuac gacccccuag ucuucccuuc cgacgaguuc     1440

gacgcgucca ucagccaagu caaugaaaag aucaaccaga gccuggcauu cauccgcaaa     1500

uccgacgaac uccuccacaa cgucaacgcg ggaaaaucca cgacaaacau caugaucacc     1560

accaucauca ucgucaucau agucauucuc cuuucucuca ucgccguggg acuacuucuc     1620

uacugcaaag cccgauaagg acuaguaaua aggaaacugu augaaugucu gugggcagga     1680

agugaagaga uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu     1740

ugaaauaaua aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1860

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1901


<210>  8054
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8054
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8055
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8055
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8056
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8056
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8057
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8057
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8058
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8058
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8059
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8059
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagau gaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8060
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8060
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau ugaaagccaa cgcaaucaca acaauacuaa ccgccguaac auuuugcuuc      240

gcgucaggcc aaaauauaac agaagaauuu uaccaaucaa caugcuccgc cguaucaaaa      300

ggauaccuag gugcauuacg aaccgguugg uacacaucag uaaucacaau agaacuuucc      360

aacauuaaag aaauaaaaug caauggcaca gacgcaaaag ucaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc cgucacagac uuacaacuau uaaugcaaag cacaccagca      480

acaggauccg gaucagcaau agcaucagga guagccgucu guaaaguacu acaccuagaa      540

ggcgaaguua auaaaauuaa aucagcuuua uuaucaacca acaaagcagu aguaucacua      600

uccggaugcg gagucuccgu ccuaacauuc aaaguacuag accucaagaa uuacauagau      660

aaacaacuac uaccaauacu caacaaacaa ucauguucaa uaccaaacau cgaaaccguc      720

auagaauuuc aacaaaaaaa uaauagacuc uuagaaauaa cacgagaauu uagcguaaac      780

gcaggaguca caaccccugu cucaacauac augcuaacca auuccgaauu auuaucacuc      840

auaaaugaca ugccaauaac uaaugaccaa aaaaaacuua ugucaaacaa cguacaaaua      900

guaagacaac aaucauauuc aauaaugugc auaaucaaag aagaaguuuu agcauaugua      960

guacaacuac cacuauaugg cgucauagac acaccaugcu ggaaauuaca cacaucaccu     1020

cuaugcacaa caaacacaaa agaaggaagc aacauuugcc uaaccagaac cgauagagga     1080

ugguacugcg auaacgcagg cucaguauca uucuucccuc aagccgaaac uugcaaaguc     1140

caaucaaaua gagucuucug cgauacaaug aacuccuuaa cuuuaccauc agaaguaaau     1200

cuaugcaacg uagauaucuu uaauccaaaa uacgauugca aaaucaugac aucaaaaaca     1260

gauguaucau cuaguguaau uaccucccua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucuaacaa augucgugga auaauaaaaa cauucucaaa cggaugcgau     1380

uauguaucaa auaaaggugu cgacaccgua ucaguaggca auacacuaua cuauguaaau     1440

aaacaagaag gacaaucacu cuacgucaaa ggugaaccaa uaauaaacuu cuacgaccca     1500

cuuguauucc caagcgacga auuugacgca ucaauaagcc aaguaaacga aaaaauaaac     1560

caaucacuag cauucaucag aaaaucagac gaacuacucc acaauguaaa ugcaggaaaa     1620

ucaacaacca auaucaugau aacaaccaua auaauaguca uaauaguaau acuauuaucc     1680

cucauagccg uuggacuacu ccuauauugu aaagcacgau aaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8061
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8061
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccaucacc accauacuca ccgcaguaac cuucugcuuc      240

gcauccggcc aaaacaucac agaagaguuc uaccagagua ccugcuccgc cgucuccaaa      300

ggcuaccuug gcgcccuccg uaccgggugg uacacauccg ucaucacaau cgaacucucc      360

aacaucaaag aaauaaagug caacggcaca gacgccaaag uaaaacugau aaagcaagaa      420

cucgacaaau acaaaaacgc cguaaccgac cuccagcuac uaaugcaauc cacucccgcc      480

accggcagcg gauccgccau cgccuccgga guagccgucu guaaagucuu acaccucgaa      540

ggcgaaguga acaaaaucaa auccgcccua cucucaacca acaaagccgu aguaucacuc      600

uccgggugcg gcguuucagu gcuaacguuc aaaguccuug accucaaaaa cuacaucgac      660

aaacaacucc uccccauccu aaauaaacaa uccugcucca uacccaacau cgagacuguc      720

aucgaguucc agcagaaaaa caaccgacuc cucgaaauca cacgcgaguu cucugucaac      780

gccggcguca caacccccgu cuccacauac augcucacca acagcgaacu ccucucccua      840

aucaaugaca ugcccaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      900

guccgccaac aauccuacag caucaugugc aucaucaaag aagaaguucu cgcauacgua      960

guacaacucc cccucuacgg agugaucgac acccccugcu ggaaacuaca caccagcccg     1020

cuuugcacca caaacaccaa ggaaggcucc aacaucugcc ucacucgaac cgaccgcggc     1080

ugguacugcg acaacgcagg cuccgucagu uucuuucccc aagcagaaac augcaaaguc     1140

caauccaacc gaguauucug cgacaccaug aacucccuca cccuaccauc cgaaguuaac     1200

cuaugcaacg uggacaucuu caaccccaag uacgacugca aaauuaugac cuccaaaacc     1260

gacguauccu ccagcgucau caccagccuc ggagcaauag ucuccugcua cggcaagacc     1320

aagugcaccg cuuccaacaa gugucgcgga aucaucaaaa ccuucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacaccgua uccguaggaa acacccuaua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca ucaucaauuu cuacgacccc     1500

cuagucuucc cuuccgacga guucgacgcg uccaucagcc aagucaauga aaagaucaac     1560

cagagccugg cauucauccg caaauccgac gaacuccucc acaacgucaa cgcgggaaaa     1620

uccacgacaa acaucaugau caccaccauc aucaucguca ucauagucau ucuccuuucu     1680

cucaucgccg ugggacuacu ucucuacugc aaagcccgau aaggacuagu gaagggaaca     1740

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca     1800

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau     1860

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1920

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1980

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     2040

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  8062
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8062
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8063
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8063
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

ggugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8064
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8064
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8065
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8065
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8066
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8066
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8067
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8067
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8068
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8068
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauugaaagc caacgcaauc acaacaauac      120

uaaccgccgu aacauuuugc uucgcgucag gccaaaauau aacagaagaa uuuuaccaau      180

caacaugcuc cgccguauca aaaggauacc uaggugcauu acgaaccggu ugguacacau      240

caguaaucac aauagaacuu uccaacauua aagaaauaaa augcaauggc acagacgcaa      300

aagucaaacu aauaaaacaa gaacuagaca aauauaaaaa cgccgucaca gacuuacaac      360

uauuaaugca aagcacacca gcaacaggau ccggaucagc aauagcauca ggaguagccg      420

ucuguaaagu acuacaccua gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa      480

ccaacaaagc aguaguauca cuauccggau gcggagucuc cguccuaaca uucaaaguac      540

uagaccucaa gaauuacaua gauaaacaac uacuaccaau acucaacaaa caaucauguu      600

caauaccaaa caucgaaacc gucauagaau uucaacaaaa aaauaauaga cucuuagaaa      660

uaacacgaga auuuagcgua aacgcaggag ucacaacccc ugucucaaca uacaugcuaa      720

ccaauuccga auuauuauca cucauaaaug acaugccaau aacuaaugac caaaaaaaac      780

uuaugucaaa caacguacaa auaguaagac aacaaucaua uucaauaaug ugcauaauca      840

aagaagaagu uuuagcauau guaguacaac uaccacuaua uggcgucaua gacacaccau      900

gcuggaaauu acacacauca ccucuaugca caacaaacac aaaagaagga agcaacauuu      960

gccuaaccag aaccgauaga ggaugguacu gcgauaacgc aggcucagua ucauucuucc     1020

cucaagccga aacuugcaaa guccaaucaa auagagucuu cugcgauaca augaacuccu     1080

uaacuuuacc aucagaagua aaucuaugca acguagauau cuuuaaucca aaauacgauu     1140

gcaaaaucau gacaucaaaa acagauguau caucuagugu aauuaccucc cuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa     1260

aaacauucuc aaacggaugc gauuauguau caaauaaagg ugucgacacc guaucaguag     1320

gcaauacacu auacuaugua aauaaacaag aaggacaauc acucuacguc aaaggugaac     1380

caauaauaaa cuucuacgac ccacuuguau ucccaagcga cgaauuugac gcaucaauaa     1440

gccaaguaaa cgaaaaaaua aaccaaucac uagcauucau cagaaaauca gacgaacuac     1500

uccacaaugu aaaugcagga aaaucaacaa ccaauaucau gauaacaacc auaauaauag     1560

ucauaauagu aauacuauua ucccucauag ccguuggacu acuccuauau uguaaagcac     1620

gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8069
<211>  1900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8069
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccauc accaccauac      120

ucaccgcagu aaccuucugc uucgcauccg gccaaaacau cacagaagag uucuaccaga      180

guaccugcuc cgccgucucc aaaggcuacc uuggcgcccu ccguaccggg ugguacacau      240

ccgucaucac aaucgaacuc uccaacauca aagaaauaaa gugcaacggc acagacgcca      300

aaguaaaacu gauaaagcaa gaacucgaca aauacaaaaa cgccguaacc gaccuccagc      360

uacuaaugca auccacuccc gccaccggca gcggauccgc caucgccucc ggaguagccg      420

ucuguaaagu cuuacaccuc gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc cguaguauca cucuccgggu gcggcguuuc agugcuaacg uucaaagucc      540

uugaccucaa aaacuacauc gacaaacaac uccuccccau ccuaaauaaa caauccugcu      600

ccauacccaa caucgagacu gucaucgagu uccagcagaa aaacaaccga cuccucgaaa      660

ucacacgcga guucucuguc aacgccggcg ucacaacccc cgucuccaca uacaugcuca      720

ccaacagcga acuccucucc cuaaucaaug acaugcccau caccaacgac caaaagaaac      780

ucaugucaaa caacguccaa aucguccgcc aacaauccua cagcaucaug ugcaucauca      840

aagaagaagu ucucgcauac guaguacaac ucccccucua cggagugauc gacacccccu      900

gcuggaaacu acacaccagc ccgcuuugca ccacaaacac caaggaaggc uccaacaucu      960

gccucacucg aaccgaccgc ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc     1020

cccaagcaga aacaugcaaa guccaaucca accgaguauu cugcgacacc augaacuccc     1080

ucacccuacc auccgaaguu aaccuaugca acguggacau cuucaacccc aaguacgacu     1140

gcaaaauuau gaccuccaaa accgacguau ccuccagcgu caucaccagc cucggagcaa     1200

uagucuccug cuacggcaag accaagugca ccgcuuccaa caagugucgc ggaaucauca     1260

aaaccuucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacacc guauccguag     1320

gaaacacccu auacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccaucaucaa uuucuacgac ccccuagucu ucccuuccga cgaguucgac gcguccauca     1440

gccaagucaa ugaaaagauc aaccagagcc uggcauucau ccgcaaaucc gacgaacucc     1500

uccacaacgu caacgcggga aaauccacga caaacaucau gaucaccacc aucaucaucg     1560

ucaucauagu cauucuccuu ucucucaucg ccgugggacu acuucucuac ugcaaagccc     1620

gauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca     1680

ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu augaaaugca     1740

uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1860

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1900


<210>  8070
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8070
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8071
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8071
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8072
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8072
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8073
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8073
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8074
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8074
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8075
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8075
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagau gaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8076
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8076
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau ugaaagccaa cgcaaucaca acaauacuaa ccgccguaac auuuugcuuc      240

gcgucaggcc aaaauauaac agaagaauuu uaccaaucaa caugcuccgc cguaucaaaa      300

ggauaccuag gugcauuacg aaccgguugg uacacaucag uaaucacaau agaacuuucc      360

aacauuaaag aaauaaaaug caauggcaca gacgcaaaag ucaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc cgucacagac uuacaacuau uaaugcaaag cacaccagca      480

acaggauccg gaucagcaau agcaucagga guagccgucu guaaaguacu acaccuagaa      540

ggcgaaguua auaaaauuaa aucagcuuua uuaucaacca acaaagcagu aguaucacua      600

uccggaugcg gagucuccgu ccuaacauuc aaaguacuag accucaagaa uuacauagau      660

aaacaacuac uaccaauacu caacaaacaa ucauguucaa uaccaaacau cgaaaccguc      720

auagaauuuc aacaaaaaaa uaauagacuc uuagaaauaa cacgagaauu uagcguaaac      780

gcaggaguca caaccccugu cucaacauac augcuaacca auuccgaauu auuaucacuc      840

auaaaugaca ugccaauaac uaaugaccaa aaaaaacuua ugucaaacaa cguacaaaua      900

guaagacaac aaucauauuc aauaaugugc auaaucaaag aagaaguuuu agcauaugua      960

guacaacuac cacuauaugg cgucauagac acaccaugcu ggaaauuaca cacaucaccu     1020

cuaugcacaa caaacacaaa agaaggaagc aacauuugcc uaaccagaac cgauagagga     1080

ugguacugcg auaacgcagg cucaguauca uucuucccuc aagccgaaac uugcaaaguc     1140

caaucaaaua gagucuucug cgauacaaug aacuccuuaa cuuuaccauc agaaguaaau     1200

cuaugcaacg uagauaucuu uaauccaaaa uacgauugca aaaucaugac aucaaaaaca     1260

gauguaucau cuaguguaau uaccucccua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucuaacaa augucgugga auaauaaaaa cauucucaaa cggaugcgau     1380

uauguaucaa auaaaggugu cgacaccgua ucaguaggca auacacuaua cuauguaaau     1440

aaacaagaag gacaaucacu cuacgucaaa ggugaaccaa uaauaaacuu cuacgaccca     1500

cuuguauucc caagcgacga auuugacgca ucaauaagcc aaguaaacga aaaaauaaac     1560

caaucacuag cauucaucag aaaaucagac gaacuacucc acaauguaaa ugcaggaaaa     1620

ucaacaacca auaucaugau aacaaccaua auaauaguca uaauaguaau acuauuaucc     1680

cucauagccg uuggacuacu ccuauauugu aaagcacgau aaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8077
<211>  1997
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8077
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccaucacc accauacuca ccgcaguaac cuucugcuuc      240

gcauccggcc aaaacaucac agaagaguuc uaccagagua ccugcuccgc cgucuccaaa      300

ggcuaccuug gcgcccuccg uaccgggugg uacacauccg ucaucacaau cgaacucucc      360

aacaucaaag aaauaaagug caacggcaca gacgccaaag uaaaacugau aaagcaagaa      420

cucgacaaau acaaaaacgc cguaaccgac cuccagcuac uaaugcaauc cacucccgcc      480

accggcagcg gauccgccau cgccuccgga guagccgucu guaaagucuu acaccucgaa      540

ggcgaaguga acaaaaucaa auccgcccua cucucaacca acaaagccgu aguaucacuc      600

uccgggugcg gcguuucagu gcuaacguuc aaaguccuug accucaaaaa cuacaucgac      660

aaacaacucc uccccauccu aaauaaacaa uccugcucca uacccaacau cgagacuguc      720

aucgaguucc agcagaaaaa caaccgacuc cucgaaauca cacgcgaguu cucugucaac      780

gccggcguca caacccccgu cuccacauac augcucacca acagcgaacu ccucucccua      840

aucaaugaca ugcccaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      900

guccgccaac aauccuacag caucaugugc aucaucaaag aagaaguucu cgcauacgua      960

guacaacucc cccucuacgg agugaucgac acccccugcu ggaaacuaca caccagcccg     1020

cuuugcacca caaacaccaa ggaaggcucc aacaucugcc ucacucgaac cgaccgcggc     1080

ugguacugcg acaacgcagg cuccgucagu uucuuucccc aagcagaaac augcaaaguc     1140

caauccaacc gaguauucug cgacaccaug aacucccuca cccuaccauc cgaaguuaac     1200

cuaugcaacg uggacaucuu caaccccaag uacgacugca aaauuaugac cuccaaaacc     1260

gacguauccu ccagcgucau caccagccuc ggagcaauag ucuccugcua cggcaagacc     1320

aagugcaccg cuuccaacaa gugucgcgga aucaucaaaa ccuucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacaccgua uccguaggaa acacccuaua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca ucaucaauuu cuacgacccc     1500

cuagucuucc cuuccgacga guucgacgcg uccaucagcc aagucaauga aaagaucaac     1560

cagagccugg cauucauccg caaauccgac gaacuccucc acaacgucaa cgcgggaaaa     1620

uccacgacaa acaucaugau caccaccauc aucaucguca ucauagucau ucuccuuucu     1680

cucaucgccg ugggacuacu ucucuacugc aaagcccgau aaggacuagu ggaagcauuu     1740

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug     1800

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu     1860

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1980

ucagagccac cagaauu                                                    1997


<210>  8078
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8078
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      420

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      480

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      540

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      660

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      720

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      780

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      900

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      960

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg     1020

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1080

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1260

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1380

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1440

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1560

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1620

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8079
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8079
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      240

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      360

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      420

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      480

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      540

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      600

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      660

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      720

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc      960

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg     1020

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1140

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1200

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1260

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1320

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1380

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1440

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1500

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1560

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1620

agccugaucg ccgugggccu ccugcuguac ugcaaggccc ggugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8080
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8080
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      180

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      240

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      300

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      360

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      420

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      480

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      540

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      600

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      660

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      720

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      780

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      840

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      900

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      960

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc     1020

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1080

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1140

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1200

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1260

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1320

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1380

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1440

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1500

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1560

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1620

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8081
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8081
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      180

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      240

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      300

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      360

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      420

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      480

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      540

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      600

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      660

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      720

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      780

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      840

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau      900

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      960

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu     1020

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1080

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1140

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1200

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1260

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1320

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1380

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1440

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1500

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1560

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1620

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8082
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8082
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      180

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      240

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      300

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      360

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      420

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      480

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      540

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      600

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      660

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      720

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      780

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      840

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      900

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      960

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga     1020

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1080

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1140

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1200

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1260

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1320

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1380

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1440

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1500

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1560

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1620

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8083
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8083
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      180

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      240

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      300

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      360

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      420

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      480

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      540

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      600

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      660

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      720

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      780

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      840

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau      900

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc      960

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc     1020

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1080

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1140

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1200

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1260

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1320

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1380

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1440

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1500

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1560

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1620

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaugaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8084
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8084
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuacuca uauugaaagc caacgcaauc acaacaauac uaaccgccgu aacauuuugc      180

uucgcgucag gccaaaauau aacagaagaa uuuuaccaau caacaugcuc cgccguauca      240

aaaggauacc uaggugcauu acgaaccggu ugguacacau caguaaucac aauagaacuu      300

uccaacauua aagaaauaaa augcaauggc acagacgcaa aagucaaacu aauaaaacaa      360

gaacuagaca aauauaaaaa cgccgucaca gacuuacaac uauuaaugca aagcacacca      420

gcaacaggau ccggaucagc aauagcauca ggaguagccg ucuguaaagu acuacaccua      480

gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa ccaacaaagc aguaguauca      540

cuauccggau gcggagucuc cguccuaaca uucaaaguac uagaccucaa gaauuacaua      600

gauaaacaac uacuaccaau acucaacaaa caaucauguu caauaccaaa caucgaaacc      660

gucauagaau uucaacaaaa aaauaauaga cucuuagaaa uaacacgaga auuuagcgua      720

aacgcaggag ucacaacccc ugucucaaca uacaugcuaa ccaauuccga auuauuauca      780

cucauaaaug acaugccaau aacuaaugac caaaaaaaac uuaugucaaa caacguacaa      840

auaguaagac aacaaucaua uucaauaaug ugcauaauca aagaagaagu uuuagcauau      900

guaguacaac uaccacuaua uggcgucaua gacacaccau gcuggaaauu acacacauca      960

ccucuaugca caacaaacac aaaagaagga agcaacauuu gccuaaccag aaccgauaga     1020

ggaugguacu gcgauaacgc aggcucagua ucauucuucc cucaagccga aacuugcaaa     1080

guccaaucaa auagagucuu cugcgauaca augaacuccu uaacuuuacc aucagaagua     1140

aaucuaugca acguagauau cuuuaaucca aaauacgauu gcaaaaucau gacaucaaaa     1200

acagauguau caucuagugu aauuaccucc cuaggagcaa uaguaagcug cuacggaaaa     1260

acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa aaacauucuc aaacggaugc     1320

gauuauguau caaauaaagg ugucgacacc guaucaguag gcaauacacu auacuaugua     1380

aauaaacaag aaggacaauc acucuacguc aaaggugaac caauaauaaa cuucuacgac     1440

ccacuuguau ucccaagcga cgaauuugac gcaucaauaa gccaaguaaa cgaaaaaaua     1500

aaccaaucac uagcauucau cagaaaauca gacgaacuac uccacaaugu aaaugcagga     1560

aaaucaacaa ccaauaucau gauaacaacc auaauaauag ucauaauagu aauacuauua     1620

ucccucauag ccguuggacu acuccuauau uguaaagcac gauaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8085
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8085
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaacuccuca uccucaaagc caacgccauc accaccauac ucaccgcagu aaccuucugc      180

uucgcauccg gccaaaacau cacagaagag uucuaccaga guaccugcuc cgccgucucc      240

aaaggcuacc uuggcgcccu ccguaccggg ugguacacau ccgucaucac aaucgaacuc      300

uccaacauca aagaaauaaa gugcaacggc acagacgcca aaguaaaacu gauaaagcaa      360

gaacucgaca aauacaaaaa cgccguaacc gaccuccagc uacuaaugca auccacuccc      420

gccaccggca gcggauccgc caucgccucc ggaguagccg ucuguaaagu cuuacaccuc      480

gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa ccaacaaagc cguaguauca      540

cucuccgggu gcggcguuuc agugcuaacg uucaaagucc uugaccucaa aaacuacauc      600

gacaaacaac uccuccccau ccuaaauaaa caauccugcu ccauacccaa caucgagacu      660

gucaucgagu uccagcagaa aaacaaccga cuccucgaaa ucacacgcga guucucuguc      720

aacgccggcg ucacaacccc cgucuccaca uacaugcuca ccaacagcga acuccucucc      780

cuaaucaaug acaugcccau caccaacgac caaaagaaac ucaugucaaa caacguccaa      840

aucguccgcc aacaauccua cagcaucaug ugcaucauca aagaagaagu ucucgcauac      900

guaguacaac ucccccucua cggagugauc gacacccccu gcuggaaacu acacaccagc      960

ccgcuuugca ccacaaacac caaggaaggc uccaacaucu gccucacucg aaccgaccgc     1020

ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc cccaagcaga aacaugcaaa     1080

guccaaucca accgaguauu cugcgacacc augaacuccc ucacccuacc auccgaaguu     1140

aaccuaugca acguggacau cuucaacccc aaguacgacu gcaaaauuau gaccuccaaa     1200

accgacguau ccuccagcgu caucaccagc cucggagcaa uagucuccug cuacggcaag     1260

accaagugca ccgcuuccaa caagugucgc ggaaucauca aaaccuucuc aaacggcugc     1320

gacuacgucu ccaacaaagg cgucgacacc guauccguag gaaacacccu auacuacguc     1380

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccaucaucaa uuucuacgac     1440

ccccuagucu ucccuuccga cgaguucgac gcguccauca gccaagucaa ugaaaagauc     1500

aaccagagcc uggcauucau ccgcaaaucc gacgaacucc uccacaacgu caacgcggga     1560

aaauccacga caaacaucau gaucaccacc aucaucaucg ucaucauagu cauucuccuu     1620

ucucucaucg ccgugggacu acuucucuac ugcaaagccc gauaaggacu aguguccacc     1680

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1740

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1860

ucagagccac cagaauu                                                    1877


<210>  8086
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8086
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8087
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8087
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccggugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8088
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8088
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8089
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8089
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8090
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8090
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8091
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8091
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaugagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8092
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8092
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauugaaa      120

gccaacgcaa ucacaacaau acuaaccgcc guaacauuuu gcuucgcguc aggccaaaau      180

auaacagaag aauuuuacca aucaacaugc uccgccguau caaaaggaua ccuaggugca      240

uuacgaaccg guugguacac aucaguaauc acaauagaac uuuccaacau uaaagaaaua      300

aaaugcaaug gcacagacgc aaaagucaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgccguca cagacuuaca acuauuaaug caaagcacac cagcaacagg auccggauca      420

gcaauagcau caggaguagc cgucuguaaa guacuacacc uagaaggcga aguuaauaaa      480

auuaaaucag cuuuauuauc aaccaacaaa gcaguaguau cacuauccgg augcggaguc      540

uccguccuaa cauucaaagu acuagaccuc aagaauuaca uagauaaaca acuacuacca      600

auacucaaca aacaaucaug uucaauacca aacaucgaaa ccgucauaga auuucaacaa      660

aaaaauaaua gacucuuaga aauaacacga gaauuuagcg uaaacgcagg agucacaacc      720

ccugucucaa cauacaugcu aaccaauucc gaauuauuau cacucauaaa ugacaugcca      780

auaacuaaug accaaaaaaa acuuauguca aacaacguac aaauaguaag acaacaauca      840

uauucaauaa ugugcauaau caaagaagaa guuuuagcau auguaguaca acuaccacua      900

uauggcguca uagacacacc augcuggaaa uuacacacau caccucuaug cacaacaaac      960

acaaaagaag gaagcaacau uugccuaacc agaaccgaua gaggauggua cugcgauaac     1020

gcaggcucag uaucauucuu cccucaagcc gaaacuugca aaguccaauc aaauagaguc     1080

uucugcgaua caaugaacuc cuuaacuuua ccaucagaag uaaaucuaug caacguagau     1140

aucuuuaauc caaaauacga uugcaaaauc augacaucaa aaacagaugu aucaucuagu     1200

guaauuaccu cccuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccucu     1260

aacaaauguc guggaauaau aaaaacauuc ucaaacggau gcgauuaugu aucaaauaaa     1320

ggugucgaca ccguaucagu aggcaauaca cuauacuaug uaaauaaaca agaaggacaa     1380

ucacucuacg ucaaagguga accaauaaua aacuucuacg acccacuugu auucccaagc     1440

gacgaauuug acgcaucaau aagccaagua aacgaaaaaa uaaaccaauc acuagcauuc     1500

aucagaaaau cagacgaacu acuccacaau guaaaugcag gaaaaucaac aaccaauauc     1560

augauaacaa ccauaauaau agucauaaua guaauacuau uaucccucau agccguugga     1620

cuacuccuau auuguaaagc acgauaagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8093
<211>  1859
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8093
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca ucaccaccau acucaccgca guaaccuucu gcuucgcauc cggccaaaac      180

aucacagaag aguucuacca gaguaccugc uccgccgucu ccaaaggcua ccuuggcgcc      240

cuccguaccg ggugguacac auccgucauc acaaucgaac ucuccaacau caaagaaaua      300

aagugcaacg gcacagacgc caaaguaaaa cugauaaagc aagaacucga caaauacaaa      360

aacgccguaa ccgaccucca gcuacuaaug caauccacuc ccgccaccgg cagcggaucc      420

gccaucgccu ccggaguagc cgucuguaaa gucuuacacc ucgaaggcga agugaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gccguaguau cacucuccgg gugcggcguu      540

ucagugcuaa cguucaaagu ccuugaccuc aaaaacuaca ucgacaaaca acuccucccc      600

auccuaaaua aacaauccug cuccauaccc aacaucgaga cugucaucga guuccagcag      660

aaaaacaacc gacuccucga aaucacacgc gaguucucug ucaacgccgg cgucacaacc      720

cccgucucca cauacaugcu caccaacagc gaacuccucu cccuaaucaa ugacaugccc      780

aucaccaacg accaaaagaa acucauguca aacaacgucc aaaucguccg ccaacaaucc      840

uacagcauca ugugcaucau caaagaagaa guucucgcau acguaguaca acucccccuc      900

uacggaguga ucgacacccc cugcuggaaa cuacacacca gcccgcuuug caccacaaac      960

accaaggaag gcuccaacau cugccucacu cgaaccgacc gcggcuggua cugcgacaac     1020

gcaggcuccg ucaguuucuu uccccaagca gaaacaugca aaguccaauc caaccgagua     1080

uucugcgaca ccaugaacuc ccucacccua ccauccgaag uuaaccuaug caacguggac     1140

aucuucaacc ccaaguacga cugcaaaauu augaccucca aaaccgacgu auccuccagc     1200

gucaucacca gccucggagc aauagucucc ugcuacggca agaccaagug caccgcuucc     1260

aacaaguguc gcggaaucau caaaaccuuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca ccguauccgu aggaaacacc cuauacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccaucauc aauuucuacg acccccuagu cuucccuucc     1440

gacgaguucg acgcguccau cagccaaguc aaugaaaaga ucaaccagag ccuggcauuc     1500

auccgcaaau ccgacgaacu ccuccacaac gucaacgcgg gaaaauccac gacaaacauc     1560

augaucacca ccaucaucau cgucaucaua gucauucucc uuucucucau cgccguggga     1620

cuacuucucu acugcaaagc ccgauaagga cuagugucca ccugucccuc cugggcugcu     1680

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1800

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1859


<210>  8094
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8094
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8095
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8095
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccggugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8096
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8096
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8097
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8097
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8098
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8098
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8099
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8099
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaugagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8100
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8100
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauugaaa gccaacgcaa ucacaacaau acuaaccgcc      120

guaacauuuu gcuucgcguc aggccaaaau auaacagaag aauuuuacca aucaacaugc      180

uccgccguau caaaaggaua ccuaggugca uuacgaaccg guugguacac aucaguaauc      240

acaauagaac uuuccaacau uaaagaaaua aaaugcaaug gcacagacgc aaaagucaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgccguca cagacuuaca acuauuaaug      360

caaagcacac cagcaacagg auccggauca gcaauagcau caggaguagc cgucuguaaa      420

guacuacacc uagaaggcga aguuaauaaa auuaaaucag cuuuauuauc aaccaacaaa      480

gcaguaguau cacuauccgg augcggaguc uccguccuaa cauucaaagu acuagaccuc      540

aagaauuaca uagauaaaca acuacuacca auacucaaca aacaaucaug uucaauacca      600

aacaucgaaa ccgucauaga auuucaacaa aaaaauaaua gacucuuaga aauaacacga      660

gaauuuagcg uaaacgcagg agucacaacc ccugucucaa cauacaugcu aaccaauucc      720

gaauuauuau cacucauaaa ugacaugcca auaacuaaug accaaaaaaa acuuauguca      780

aacaacguac aaauaguaag acaacaauca uauucaauaa ugugcauaau caaagaagaa      840

guuuuagcau auguaguaca acuaccacua uauggcguca uagacacacc augcuggaaa      900

uuacacacau caccucuaug cacaacaaac acaaaagaag gaagcaacau uugccuaacc      960

agaaccgaua gaggauggua cugcgauaac gcaggcucag uaucauucuu cccucaagcc     1020

gaaacuugca aaguccaauc aaauagaguc uucugcgaua caaugaacuc cuuaacuuua     1080

ccaucagaag uaaaucuaug caacguagau aucuuuaauc caaaauacga uugcaaaauc     1140

augacaucaa aaacagaugu aucaucuagu guaauuaccu cccuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccucu aacaaauguc guggaauaau aaaaacauuc     1260

ucaaacggau gcgauuaugu aucaaauaaa ggugucgaca ccguaucagu aggcaauaca     1320

cuauacuaug uaaauaaaca agaaggacaa ucacucuacg ucaaagguga accaauaaua     1380

aacuucuacg acccacuugu auucccaagc gacgaauuug acgcaucaau aagccaagua     1440

aacgaaaaaa uaaaccaauc acuagcauuc aucagaaaau cagacgaacu acuccacaau     1500

guaaaugcag gaaaaucaac aaccaauauc augauaacaa ccauaauaau agucauaaua     1560

guaauacuau uaucccucau agccguugga cuacuccuau auuguaaagc acgauaagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8101
<211>  1829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8101
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca ucaccaccau acucaccgca      120

guaaccuucu gcuucgcauc cggccaaaac aucacagaag aguucuacca gaguaccugc      180

uccgccgucu ccaaaggcua ccuuggcgcc cuccguaccg ggugguacac auccgucauc      240

acaaucgaac ucuccaacau caaagaaaua aagugcaacg gcacagacgc caaaguaaaa      300

cugauaaagc aagaacucga caaauacaaa aacgccguaa ccgaccucca gcuacuaaug      360

caauccacuc ccgccaccgg cagcggaucc gccaucgccu ccggaguagc cgucuguaaa      420

gucuuacacc ucgaaggcga agugaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gccguaguau cacucuccgg gugcggcguu ucagugcuaa cguucaaagu ccuugaccuc      540

aaaaacuaca ucgacaaaca acuccucccc auccuaaaua aacaauccug cuccauaccc      600

aacaucgaga cugucaucga guuccagcag aaaaacaacc gacuccucga aaucacacgc      660

gaguucucug ucaacgccgg cgucacaacc cccgucucca cauacaugcu caccaacagc      720

gaacuccucu cccuaaucaa ugacaugccc aucaccaacg accaaaagaa acucauguca      780

aacaacgucc aaaucguccg ccaacaaucc uacagcauca ugugcaucau caaagaagaa      840

guucucgcau acguaguaca acucccccuc uacggaguga ucgacacccc cugcuggaaa      900

cuacacacca gcccgcuuug caccacaaac accaaggaag gcuccaacau cugccucacu      960

cgaaccgacc gcggcuggua cugcgacaac gcaggcuccg ucaguuucuu uccccaagca     1020

gaaacaugca aaguccaauc caaccgagua uucugcgaca ccaugaacuc ccucacccua     1080

ccauccgaag uuaaccuaug caacguggac aucuucaacc ccaaguacga cugcaaaauu     1140

augaccucca aaaccgacgu auccuccagc gucaucacca gccucggagc aauagucucc     1200

ugcuacggca agaccaagug caccgcuucc aacaaguguc gcggaaucau caaaaccuuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca ccguauccgu aggaaacacc     1320

cuauacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccaucauc     1380

aauuucuacg acccccuagu cuucccuucc gacgaguucg acgcguccau cagccaaguc     1440

aaugaaaaga ucaaccagag ccuggcauuc auccgcaaau ccgacgaacu ccuccacaac     1500

gucaacgcgg gaaaauccac gacaaacauc augaucacca ccaucaucau cgucaucaua     1560

gucauucucc uuucucucau cgccguggga cuacuucucu acugcaaagc ccgauaagga     1620

cuagugucca ccugucccuc cugggcugcu ggauugucuc guuuuccugc caaauaaaca     1680

ggaucagcgc uuuacagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1800

caaaggcucu uuucagagcc accagaauu                                       1829


<210>  8102
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8102
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8103
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8103
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccggug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8104
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8104
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8105
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8105
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8106
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8106
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8107
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8107
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaug aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8108
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8108
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu gaaagccaac gcaaucacaa caauacuaac cgccguaaca      180

uuuugcuucg cgucaggcca aaauauaaca gaagaauuuu accaaucaac augcuccgcc      240

guaucaaaag gauaccuagg ugcauuacga accgguuggu acacaucagu aaucacaaua      300

gaacuuucca acauuaaaga aauaaaaugc aauggcacag acgcaaaagu caaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgcc gucacagacu uacaacuauu aaugcaaagc      420

acaccagcaa caggauccgg aucagcaaua gcaucaggag uagccgucug uaaaguacua      480

caccuagaag gcgaaguuaa uaaaauuaaa ucagcuuuau uaucaaccaa caaagcagua      540

guaucacuau ccggaugcgg agucuccguc cuaacauuca aaguacuaga ccucaagaau      600

uacauagaua aacaacuacu accaauacuc aacaaacaau cauguucaau accaaacauc      660

gaaaccguca uagaauuuca acaaaaaaau aauagacucu uagaaauaac acgagaauuu      720

agcguaaacg caggagucac aaccccuguc ucaacauaca ugcuaaccaa uuccgaauua      780

uuaucacuca uaaaugacau gccaauaacu aaugaccaaa aaaaacuuau gucaaacaac      840

guacaaauag uaagacaaca aucauauuca auaaugugca uaaucaaaga agaaguuuua      900

gcauauguag uacaacuacc acuauauggc gucauagaca caccaugcug gaaauuacac      960

acaucaccuc uaugcacaac aaacacaaaa gaaggaagca acauuugccu aaccagaacc     1020

gauagaggau gguacugcga uaacgcaggc ucaguaucau ucuucccuca agccgaaacu     1080

ugcaaagucc aaucaaauag agucuucugc gauacaauga acuccuuaac uuuaccauca     1140

gaaguaaauc uaugcaacgu agauaucuuu aauccaaaau acgauugcaa aaucaugaca     1200

ucaaaaacag auguaucauc uaguguaauu accucccuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucuaacaaa ugucguggaa uaauaaaaac auucucaaac     1320

ggaugcgauu auguaucaaa uaaagguguc gacaccguau caguaggcaa uacacuauac     1380

uauguaaaua aacaagaagg acaaucacuc uacgucaaag gugaaccaau aauaaacuuc     1440

uacgacccac uuguauuccc aagcgacgaa uuugacgcau caauaagcca aguaaacgaa     1500

aaaauaaacc aaucacuagc auucaucaga aaaucagacg aacuacucca caauguaaau     1560

gcaggaaaau caacaaccaa uaucaugaua acaaccauaa uaauagucau aauaguaaua     1620

cuauuauccc ucauagccgu uggacuacuc cuauauugua aagcacgaua aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8109
<211>  1883
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8109
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccaucacca ccauacucac cgcaguaacc      180

uucugcuucg cauccggcca aaacaucaca gaagaguucu accagaguac cugcuccgcc      240

gucuccaaag gcuaccuugg cgcccuccgu accggguggu acacauccgu caucacaauc      300

gaacucucca acaucaaaga aauaaagugc aacggcacag acgccaaagu aaaacugaua      360

aagcaagaac ucgacaaaua caaaaacgcc guaaccgacc uccagcuacu aaugcaaucc      420

acucccgcca ccggcagcgg auccgccauc gccuccggag uagccgucug uaaagucuua      480

caccucgaag gcgaagugaa caaaaucaaa uccgcccuac ucucaaccaa caaagccgua      540

guaucacucu ccgggugcgg cguuucagug cuaacguuca aaguccuuga ccucaaaaac      600

uacaucgaca aacaacuccu ccccauccua aauaaacaau ccugcuccau acccaacauc      660

gagacuguca ucgaguucca gcagaaaaac aaccgacucc ucgaaaucac acgcgaguuc      720

ucugucaacg ccggcgucac aacccccguc uccacauaca ugcucaccaa cagcgaacuc      780

cucucccuaa ucaaugacau gcccaucacc aacgaccaaa agaaacucau gucaaacaac      840

guccaaaucg uccgccaaca auccuacagc aucaugugca ucaucaaaga agaaguucuc      900

gcauacguag uacaacuccc ccucuacgga gugaucgaca cccccugcug gaaacuacac      960

accagcccgc uuugcaccac aaacaccaag gaaggcucca acaucugccu cacucgaacc     1020

gaccgcggcu gguacugcga caacgcaggc uccgucaguu ucuuucccca agcagaaaca     1080

ugcaaagucc aauccaaccg aguauucugc gacaccauga acucccucac ccuaccaucc     1140

gaaguuaacc uaugcaacgu ggacaucuuc aaccccaagu acgacugcaa aauuaugacc     1200

uccaaaaccg acguauccuc cagcgucauc accagccucg gagcaauagu cuccugcuac     1260

ggcaagacca agugcaccgc uuccaacaag ugucgcggaa ucaucaaaac cuucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacaccguau ccguaggaaa cacccuauac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau caucaauuuc     1440

uacgaccccc uagucuuccc uuccgacgag uucgacgcgu ccaucagcca agucaaugaa     1500

aagaucaacc agagccuggc auucauccgc aaauccgacg aacuccucca caacgucaac     1560

gcgggaaaau ccacgacaaa caucaugauc accaccauca ucaucgucau cauagucauu     1620

cuccuuucuc ucaucgccgu gggacuacuu cucuacugca aagcccgaua aggacuagug     1680

uccaccuguc ccuccugggc ugcuggauug ucucguuuuc cugccaaaua aacaggauca     1740

gcgcuuuaca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1860

cucuuuucag agccaccaga auu                                             1883


<210>  8110
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8110
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8111
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8111
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccggugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8112
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8112
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8113
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8113
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8114
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8114
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8115
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8115
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaugagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8116
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8116
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauugaa agccaacgca      120

aucacaacaa uacuaaccgc cguaacauuu ugcuucgcgu caggccaaaa uauaacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucaaaaggau accuaggugc auuacgaacc      240

gguugguaca caucaguaau cacaauagaa cuuuccaaca uuaaagaaau aaaaugcaau      300

ggcacagacg caaaagucaa acuaauaaaa caagaacuag acaaauauaa aaacgccguc      360

acagacuuac aacuauuaau gcaaagcaca ccagcaacag gauccggauc agcaauagca      420

ucaggaguag ccgucuguaa aguacuacac cuagaaggcg aaguuaauaa aauuaaauca      480

gcuuuauuau caaccaacaa agcaguagua ucacuauccg gaugcggagu cuccguccua      540

acauucaaag uacuagaccu caagaauuac auagauaaac aacuacuacc aauacucaac      600

aaacaaucau guucaauacc aaacaucgaa accgucauag aauuucaaca aaaaaauaau      660

agacucuuag aaauaacacg agaauuuagc guaaacgcag gagucacaac cccugucuca      720

acauacaugc uaaccaauuc cgaauuauua ucacucauaa augacaugcc aauaacuaau      780

gaccaaaaaa aacuuauguc aaacaacgua caaauaguaa gacaacaauc auauucaaua      840

augugcauaa ucaaagaaga aguuuuagca uauguaguac aacuaccacu auauggcguc      900

auagacacac caugcuggaa auuacacaca ucaccucuau gcacaacaaa cacaaaagaa      960

ggaagcaaca uuugccuaac cagaaccgau agaggauggu acugcgauaa cgcaggcuca     1020

guaucauucu ucccucaagc cgaaacuugc aaaguccaau caaauagagu cuucugcgau     1080

acaaugaacu ccuuaacuuu accaucagaa guaaaucuau gcaacguaga uaucuuuaau     1140

ccaaaauacg auugcaaaau caugacauca aaaacagaug uaucaucuag uguaauuacc     1200

ucccuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc uaacaaaugu     1260

cguggaauaa uaaaaacauu cucaaacgga ugcgauuaug uaucaaauaa aggugucgac     1320

accguaucag uaggcaauac acuauacuau guaaauaaac aagaaggaca aucacucuac     1380

gucaaaggug aaccaauaau aaacuucuac gacccacuug uauucccaag cgacgaauuu     1440

gacgcaucaa uaagccaagu aaacgaaaaa auaaaccaau cacuagcauu caucagaaaa     1500

ucagacgaac uacuccacaa uguaaaugca ggaaaaucaa caaccaauau caugauaaca     1560

accauaauaa uagucauaau aguaauacua uuaucccuca uagccguugg acuacuccua     1620

uauuguaaag cacgauaagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8117
<211>  1850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8117
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

aucaccacca uacucaccgc aguaaccuuc ugcuucgcau ccggccaaaa caucacagaa      180

gaguucuacc agaguaccug cuccgccguc uccaaaggcu accuuggcgc ccuccguacc      240

gggugguaca cauccgucau cacaaucgaa cucuccaaca ucaaagaaau aaagugcaac      300

ggcacagacg ccaaaguaaa acugauaaag caagaacucg acaaauacaa aaacgccgua      360

accgaccucc agcuacuaau gcaauccacu cccgccaccg gcagcggauc cgccaucgcc      420

uccggaguag ccgucuguaa agucuuacac cucgaaggcg aagugaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agccguagua ucacucuccg ggugcggcgu uucagugcua      540

acguucaaag uccuugaccu caaaaacuac aucgacaaac aacuccuccc cauccuaaau      600

aaacaauccu gcuccauacc caacaucgag acugucaucg aguuccagca gaaaaacaac      660

cgacuccucg aaaucacacg cgaguucucu gucaacgccg gcgucacaac ccccgucucc      720

acauacaugc ucaccaacag cgaacuccuc ucccuaauca augacaugcc caucaccaac      780

gaccaaaaga aacucauguc aaacaacguc caaaucgucc gccaacaauc cuacagcauc      840

augugcauca ucaaagaaga aguucucgca uacguaguac aacucccccu cuacggagug      900

aucgacaccc ccugcuggaa acuacacacc agcccgcuuu gcaccacaaa caccaaggaa      960

ggcuccaaca ucugccucac ucgaaccgac cgcggcuggu acugcgacaa cgcaggcucc     1020

gucaguuucu uuccccaagc agaaacaugc aaaguccaau ccaaccgagu auucugcgac     1080

accaugaacu cccucacccu accauccgaa guuaaccuau gcaacgugga caucuucaac     1140

cccaaguacg acugcaaaau uaugaccucc aaaaccgacg uauccuccag cgucaucacc     1200

agccucggag caauagucuc cugcuacggc aagaccaagu gcaccgcuuc caacaagugu     1260

cgcggaauca ucaaaaccuu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

accguauccg uaggaaacac ccuauacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccaucau caauuucuac gacccccuag ucuucccuuc cgacgaguuc     1440

gacgcgucca ucagccaagu caaugaaaag aucaaccaga gccuggcauu cauccgcaaa     1500

uccgacgaac uccuccacaa cgucaacgcg ggaaaaucca cgacaaacau caugaucacc     1560

accaucauca ucgucaucau agucauucuc cuuucucuca ucgccguggg acuacuucuc     1620

uacugcaaag cccgauaagg acuagugucc accugucccu ccugggcugc uggauugucu     1680

cguuuuccug ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1800

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1850


<210>  8118
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8118
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8119
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8119
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccggugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8120
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8120
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8121
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8121
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8122
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8122
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8123
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8123
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8124
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8124
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauugaa agccaacgca      120

aucacaacaa uacuaaccgc cguaacauuu ugcuucgcgu caggccaaaa uauaacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucaaaaggau accuaggugc auuacgaacc      240

gguugguaca caucaguaau cacaauagaa cuuuccaaca uuaaagaaau aaaaugcaau      300

ggcacagacg caaaagucaa acuaauaaaa caagaacuag acaaauauaa aaacgccguc      360

acagacuuac aacuauuaau gcaaagcaca ccagcaacag gauccggauc agcaauagca      420

ucaggaguag ccgucuguaa aguacuacac cuagaaggcg aaguuaauaa aauuaaauca      480

gcuuuauuau caaccaacaa agcaguagua ucacuauccg gaugcggagu cuccguccua      540

acauucaaag uacuagaccu caagaauuac auagauaaac aacuacuacc aauacucaac      600

aaacaaucau guucaauacc aaacaucgaa accgucauag aauuucaaca aaaaaauaau      660

agacucuuag aaauaacacg agaauuuagc guaaacgcag gagucacaac cccugucuca      720

acauacaugc uaaccaauuc cgaauuauua ucacucauaa augacaugcc aauaacuaau      780

gaccaaaaaa aacuuauguc aaacaacgua caaauaguaa gacaacaauc auauucaaua      840

augugcauaa ucaaagaaga aguuuuagca uauguaguac aacuaccacu auauggcguc      900

auagacacac caugcuggaa auuacacaca ucaccucuau gcacaacaaa cacaaaagaa      960

ggaagcaaca uuugccuaac cagaaccgau agaggauggu acugcgauaa cgcaggcuca     1020

guaucauucu ucccucaagc cgaaacuugc aaaguccaau caaauagagu cuucugcgau     1080

acaaugaacu ccuuaacuuu accaucagaa guaaaucuau gcaacguaga uaucuuuaau     1140

ccaaaauacg auugcaaaau caugacauca aaaacagaug uaucaucuag uguaauuacc     1200

ucccuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc uaacaaaugu     1260

cguggaauaa uaaaaacauu cucaaacgga ugcgauuaug uaucaaauaa aggugucgac     1320

accguaucag uaggcaauac acuauacuau guaaauaaac aagaaggaca aucacucuac     1380

gucaaaggug aaccaauaau aaacuucuac gacccacuug uauucccaag cgacgaauuu     1440

gacgcaucaa uaagccaagu aaacgaaaaa auaaaccaau cacuagcauu caucagaaaa     1500

ucagacgaac uacuccacaa uguaaaugca ggaaaaucaa caaccaauau caugauaaca     1560

accauaauaa uagucauaau aguaauacua uuaucccuca uagccguugg acuacuccua     1620

uauuguaaag cacgauaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8125
<211>  1917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8125
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

aucaccacca uacucaccgc aguaaccuuc ugcuucgcau ccggccaaaa caucacagaa      180

gaguucuacc agaguaccug cuccgccguc uccaaaggcu accuuggcgc ccuccguacc      240

gggugguaca cauccgucau cacaaucgaa cucuccaaca ucaaagaaau aaagugcaac      300

ggcacagacg ccaaaguaaa acugauaaag caagaacucg acaaauacaa aaacgccgua      360

accgaccucc agcuacuaau gcaauccacu cccgccaccg gcagcggauc cgccaucgcc      420

uccggaguag ccgucuguaa agucuuacac cucgaaggcg aagugaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agccguagua ucacucuccg ggugcggcgu uucagugcua      540

acguucaaag uccuugaccu caaaaacuac aucgacaaac aacuccuccc cauccuaaau      600

aaacaauccu gcuccauacc caacaucgag acugucaucg aguuccagca gaaaaacaac      660

cgacuccucg aaaucacacg cgaguucucu gucaacgccg gcgucacaac ccccgucucc      720

acauacaugc ucaccaacag cgaacuccuc ucccuaauca augacaugcc caucaccaac      780

gaccaaaaga aacucauguc aaacaacguc caaaucgucc gccaacaauc cuacagcauc      840

augugcauca ucaaagaaga aguucucgca uacguaguac aacucccccu cuacggagug      900

aucgacaccc ccugcuggaa acuacacacc agcccgcuuu gcaccacaaa caccaaggaa      960

ggcuccaaca ucugccucac ucgaaccgac cgcggcuggu acugcgacaa cgcaggcucc     1020

gucaguuucu uuccccaagc agaaacaugc aaaguccaau ccaaccgagu auucugcgac     1080

accaugaacu cccucacccu accauccgaa guuaaccuau gcaacgugga caucuucaac     1140

cccaaguacg acugcaaaau uaugaccucc aaaaccgacg uauccuccag cgucaucacc     1200

agccucggag caauagucuc cugcuacggc aagaccaagu gcaccgcuuc caacaagugu     1260

cgcggaauca ucaaaaccuu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

accguauccg uaggaaacac ccuauacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccaucau caauuucuac gacccccuag ucuucccuuc cgacgaguuc     1440

gacgcgucca ucagccaagu caaugaaaag aucaaccaga gccuggcauu cauccgcaaa     1500

uccgacgaac uccuccacaa cgucaacgcg ggaaaaucca cgacaaacau caugaucacc     1560

accaucauca ucgucaucau agucauucuc cuuucucuca ucgccguggg acuacuucuc     1620

uacugcaaag cccgauaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc     1680

cuucucccag gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa     1740

aucaugacuu accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1860

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1917


<210>  8126
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8126
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8127
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8127
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccggugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8128
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8128
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8129
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8129
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8130
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8130
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8131
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8131
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8132
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8132
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauugaa agccaacgca      120

aucacaacaa uacuaaccgc cguaacauuu ugcuucgcgu caggccaaaa uauaacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucaaaaggau accuaggugc auuacgaacc      240

gguugguaca caucaguaau cacaauagaa cuuuccaaca uuaaagaaau aaaaugcaau      300

ggcacagacg caaaagucaa acuaauaaaa caagaacuag acaaauauaa aaacgccguc      360

acagacuuac aacuauuaau gcaaagcaca ccagcaacag gauccggauc agcaauagca      420

ucaggaguag ccgucuguaa aguacuacac cuagaaggcg aaguuaauaa aauuaaauca      480

gcuuuauuau caaccaacaa agcaguagua ucacuauccg gaugcggagu cuccguccua      540

acauucaaag uacuagaccu caagaauuac auagauaaac aacuacuacc aauacucaac      600

aaacaaucau guucaauacc aaacaucgaa accgucauag aauuucaaca aaaaaauaau      660

agacucuuag aaauaacacg agaauuuagc guaaacgcag gagucacaac cccugucuca      720

acauacaugc uaaccaauuc cgaauuauua ucacucauaa augacaugcc aauaacuaau      780

gaccaaaaaa aacuuauguc aaacaacgua caaauaguaa gacaacaauc auauucaaua      840

augugcauaa ucaaagaaga aguuuuagca uauguaguac aacuaccacu auauggcguc      900

auagacacac caugcuggaa auuacacaca ucaccucuau gcacaacaaa cacaaaagaa      960

ggaagcaaca uuugccuaac cagaaccgau agaggauggu acugcgauaa cgcaggcuca     1020

guaucauucu ucccucaagc cgaaacuugc aaaguccaau caaauagagu cuucugcgau     1080

acaaugaacu ccuuaacuuu accaucagaa guaaaucuau gcaacguaga uaucuuuaau     1140

ccaaaauacg auugcaaaau caugacauca aaaacagaug uaucaucuag uguaauuacc     1200

ucccuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc uaacaaaugu     1260

cguggaauaa uaaaaacauu cucaaacgga ugcgauuaug uaucaaauaa aggugucgac     1320

accguaucag uaggcaauac acuauacuau guaaauaaac aagaaggaca aucacucuac     1380

gucaaaggug aaccaauaau aaacuucuac gacccacuug uauucccaag cgacgaauuu     1440

gacgcaucaa uaagccaagu aaacgaaaaa auaaaccaau cacuagcauu caucagaaaa     1500

ucagacgaac uacuccacaa uguaaaugca ggaaaaucaa caaccaauau caugauaaca     1560

accauaauaa uagucauaau aguaauacua uuaucccuca uagccguugg acuacuccua     1620

uauuguaaag cacgauaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8133
<211>  2133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8133
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

aucaccacca uacucaccgc aguaaccuuc ugcuucgcau ccggccaaaa caucacagaa      180

gaguucuacc agaguaccug cuccgccguc uccaaaggcu accuuggcgc ccuccguacc      240

gggugguaca cauccgucau cacaaucgaa cucuccaaca ucaaagaaau aaagugcaac      300

ggcacagacg ccaaaguaaa acugauaaag caagaacucg acaaauacaa aaacgccgua      360

accgaccucc agcuacuaau gcaauccacu cccgccaccg gcagcggauc cgccaucgcc      420

uccggaguag ccgucuguaa agucuuacac cucgaaggcg aagugaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agccguagua ucacucuccg ggugcggcgu uucagugcua      540

acguucaaag uccuugaccu caaaaacuac aucgacaaac aacuccuccc cauccuaaau      600

aaacaauccu gcuccauacc caacaucgag acugucaucg aguuccagca gaaaaacaac      660

cgacuccucg aaaucacacg cgaguucucu gucaacgccg gcgucacaac ccccgucucc      720

acauacaugc ucaccaacag cgaacuccuc ucccuaauca augacaugcc caucaccaac      780

gaccaaaaga aacucauguc aaacaacguc caaaucgucc gccaacaauc cuacagcauc      840

augugcauca ucaaagaaga aguucucgca uacguaguac aacucccccu cuacggagug      900

aucgacaccc ccugcuggaa acuacacacc agcccgcuuu gcaccacaaa caccaaggaa      960

ggcuccaaca ucugccucac ucgaaccgac cgcggcuggu acugcgacaa cgcaggcucc     1020

gucaguuucu uuccccaagc agaaacaugc aaaguccaau ccaaccgagu auucugcgac     1080

accaugaacu cccucacccu accauccgaa guuaaccuau gcaacgugga caucuucaac     1140

cccaaguacg acugcaaaau uaugaccucc aaaaccgacg uauccuccag cgucaucacc     1200

agccucggag caauagucuc cugcuacggc aagaccaagu gcaccgcuuc caacaagugu     1260

cgcggaauca ucaaaaccuu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

accguauccg uaggaaacac ccuauacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccaucau caauuucuac gacccccuag ucuucccuuc cgacgaguuc     1440

gacgcgucca ucagccaagu caaugaaaag aucaaccaga gccuggcauu cauccgcaaa     1500

uccgacgaac uccuccacaa cgucaacgcg ggaaaaucca cgacaaacau caugaucacc     1560

accaucauca ucgucaucau agucauucuc cuuucucuca ucgccguggg acuacuucuc     1620

uacugcaaag cccgauaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc     1680

acaauuaauu aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug     1740

aucaacaccg caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca     1800

gcuugcuuag auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa     1860

aaaggccaca aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua     1920

aagaaauaaa ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa     1980

uaaaaauuaa aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2100

cccccaaagg cucuuuucag agccaccaga auu                                  2133


<210>  8134
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8134
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcggacc      240

ggcugguaca ccuccgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

gggaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcaguccacc ccggcaaccg gcuccggcuc cgccaucgcg      420

agcggcgucg ccgugugcaa ggugcugcac cucgaggggg aggucaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccguggug agccucuccg gcugcggcgu cagcgugcug      540

accuucaagg ugcuggaccu caagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcuccauccc caacaucgag acggugaucg aguuccagca gaagaacaac      660

cggcuccugg agaucacccg cgaguucagc gugaacgccg gggucaccac ccccgugucc      720

acguacaugc ugaccaacag cgagcuccug ucccugauca acgacaugcc gaucaccaac      780

gaccagaaga agcucaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcg uacguggucc agcugccccu cuacggcgug      900

aucgacaccc ccugcuggaa gcugcacacg agcccccugu gcaccaccaa caccaaggag      960

ggguccaaca ucugccucac gcgcaccgac cggggcuggu acugcgacaa cgccggcagc     1020

gucuccuucu ucccgcaggc cgagaccugc aaggugcaga gcaaccgcgu guucugcgac     1080

accaugaacu cccugacgcu gcccagcgag guaaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ugagcuccag cgugaucacc     1200

ucccuggggg ccaucgucag cugcuacggc aagacgaagu gcaccgccag caacaagugc     1260

cgggggauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accguguccg ucgggaacac ccuguacuac gugaacaagc aggagggcca gagccucuac     1380

gugaaggggg agcccaucau caacuucuac gacccgcugg ucuuccccuc cgacgaguuc     1440

gacgcgagca ucucccaggu gaacgagaag aucaaccaga gccuggccuu cauccgcaag     1500

uccgacgagc ugcuccacaa cgugaacgcc ggcaagagca cgaccaacau caugaucacc     1560

accaucauca ucgucaucau cgugauccug cugucccuca ucgccguggg gcugcugcuc     1620

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8135
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8135
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcc      120

aucaccacca uccugacggc ggugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc aguccacgug cagcgccguc uccaaggggu accucggcgc ccugcgcacc      240

gggugguaca ccagcgugau caccaucgag cuguccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcucaucaag caggagcugg acaaguacaa gaacgcgguc      360

acggaccugc agcuccugau gcagagcacc cccgccaccg gguccggcag cgccaucgcc      420

uccggcgugg cggugugcaa gguccugcac cucgaggggg aggugaacaa gaucaagagc      480

gcccugcugu ccaccaacaa ggccgugguc agccucuccg gcugcggggu gagcgugcug      540

acguucaagg uccuggaccu caagaacuac aucgacaagc agcugcugcc gauccucaac      600

aagcaguccu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

cggcugcugg agaucacccg cgaguucucc gugaacgccg gcgucaccac gcccgugagc      720

accuacaugc ucaccaacuc cgagcugcug agccucauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucgucc ggcagcaguc cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggucc agcucccgcu guacggggug      900

aucgacacgc ccugcuggaa gcugcacacc agcccccucu gcaccaccaa cacgaaggag      960

ggcuccaaca ucugccugac ccgcaccgac cggggcuggu acugcgacaa cgcggggucc     1020

gugagcuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu guucugcgac     1080

acgaugaaca gccugacccu cccguccgag gucaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg uguccagcuc cgucaucacg     1200

agccugggcg ccaucguguc cugcuacggg aagaccaagu gcaccgccag caacaagugc     1260

cggggcauca ucaagaccuu cuccaacggc ugcgacuacg ugagcaacaa gggggucgac     1320

acgguguccg ugggcaacac ccucuacuac gucaacaagc aggaggggca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguucccgag cgacgaguuc     1440

gacgccucca ucagccaggu caacgagaag aucaaccagu cccucgcguu cauccgcaag     1500

agcgacgagc ugcugcacaa cgugaacgcc gggaagucca ccaccaacau caugaucacc     1560

acgaucauca ucgugaucau cgucauccuc cugagccuga ucgccguggg ccuccugcug     1620

uacugcaagg cccggugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8136
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8136
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcucc ucauccucaa ggccaacgcc      120

aucaccacca uccucaccgc cgucaccuuc ugcuucgccu ccggccagaa caucaccgag      180

gaguucuacc aguccaccug cuccgccguc uccaagggcu accucggcgc ccuccgcacc      240

ggcugguaca ccuccgucau caccaucgag cucuccaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggucaa gcucaucaag caggagcucg acaaguacaa gaacgccguc      360

accgaccucc agcuccucau gcaguccacc cccgccaccg gcuccggcuc cgccaucgcc      420

uccggcgucg ccgucugcaa gguccuccac cucgagggcg aggucaacaa gaucaagucc      480

gcccuccucu ccaccaacaa ggccgucguc ucccucuccg gcugcggcgu cuccguccuc      540

accuucaagg uccucgaccu caagaacuac aucgacaagc agcuccuccc cauccucaac      600

aagcaguccu gcuccauccc caacaucgag accgucaucg aguuccagca gaagaacaac      660

cgccuccucg agaucacccg cgaguucucc gucaacgccg gcgucaccac ccccgucucc      720

accuacaugc ucaccaacuc cgagcuccuc ucccucauca acgacaugcc caucaccaac      780

gaccagaaga agcucauguc caacaacguc cagaucgucc gccagcaguc cuacuccauc      840

augugcauca ucaaggagga gguccucgcc uacgucgucc agcucccccu cuacggcguc      900

aucgacaccc ccugcuggaa gcuccacacc uccccccucu gcaccaccaa caccaaggag      960

ggcuccaaca ucugccucac ccgcaccgac cgcggcuggu acugcgacaa cgccggcucc     1020

gucuccuucu ucccccaggc cgagaccugc aagguccagu ccaaccgcgu cuucugcgac     1080

accaugaacu cccucacccu ccccuccgag gucaaccucu gcaacgucga caucuucaac     1140

cccaaguacg acugcaagau caugaccucc aagaccgacg ucuccuccuc cgucaucacc     1200

ucccucggcg ccaucgucuc cugcuacggc aagaccaagu gcaccgccuc caacaagugc     1260

cgcggcauca ucaagaccuu cuccaacggc ugcgacuacg ucuccaacaa gggcgucgac     1320

accgucuccg ucggcaacac ccucuacuac gucaacaagc aggagggcca gucccucuac     1380

gucaagggcg agcccaucau caacuucuac gacccccucg ucuuccccuc cgacgaguuc     1440

gacgccucca ucucccaggu caacgagaag aucaaccagu cccucgccuu cauccgcaag     1500

uccgacgagc uccuccacaa cgucaacgcc ggcaagucca ccaccaacau caugaucacc     1560

accaucauca ucgucaucau cgucauccuc cucucccuca ucgccgucgg ccuccuccuc     1620

uacugcaagg cccgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8137
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8137
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccuuaa ggccaacgcu      120

auuaccacaa uacugacugc agugacguuc ugcuuugcca gcggccagaa uaucaccgaa      180

gaguucuacc aauccacaug uucugcgguc ucaaaagggu auuugggagc uuuaagaacu      240

gguugguaca ccaguguuau uacaaucgaa cugagcaaca uuaaggagau caaaugcaau      300

ggcaccgacg ccaaggugaa acuaauaaag caggaacucg auaaguauaa aaacgcagua      360

acugaccugc agcuucugau gcaguccaca cccgccaccg ggucuggauc ggcuaucgca      420

ucaggcgugg ccgucuguaa gguguugcac cucgagggug agguuaauaa aauuaagagc      480

gcucugcuga guacgaacaa agccgugguc ucccucucug ggugcggagu gagcguauua      540

acuuuuaagg uucuggaucu uaagaauuac aucgacaaac aauugcugcc uauucuaaac      600

aagcaguccu guucaauccc aaauauagaa accgugauug aguuccagca gaaaaacaau      660

aggcuccugg aaaucacacg ggaguuuagu gucaacgcgg gcgugacuac cccggugagc      720

acauauaugc uuaccaauuc ugagcuguug ucccucauua acgauaugcc caucacgaau      780

gaccaaaaga aacugauguc aaacaacguc cagaucguuc gccagcagag cuacaguauu      840

augugcauaa ucaaggaaga gguguuagca uauguagugc aacugccucu cuacggcguc      900

auugauacuc cauguuggaa acuucauaca ucuccccugu gcaccacuaa uacaaaggaa      960

ggguccaaca ucuguuugac ccgaacggac cguggauggu acugcgauaa ugccgguagc     1020

gugucguucu uuccucaggc ugagaccugu aagguucagu cuaacagagu guucugcgac     1080

acaaugaacu cccuaacucu gccaucagaa gucaaucucu gcaaugugga uauauuuaac     1140

cccaaauaug acuguaagau uaugaccagu aaaacagaug uaagcuccuc uguuaucacu     1200

agccugggcg ccaucguguc augcuacggg aagaccaaau guacagcaag uaauaagugc     1260

aggggaauua ucaagaccuu cuccaacggc ugugacuaug ucagcaauaa agguguggac     1320

acugucucug uggggaacac gcuuuacuau guuaauaagc aagagggaca gucacuguac     1380

gugaaaggcg agccuauuau aaacuuuuau gauccauugg uauucccgag ugacgaauuu     1440

gaugcuagca ucucccaggu caaugagaag auuaaccagu cucucgccuu cauccggaaa     1500

ucggacgaac uguuacacaa cgugaaugcg ggcaagagca caaccaacau caugauuacu     1560

accauaauca uuguuaucau ugugauccug cuaucccuca uagccgucgg gcugcuuuug     1620

uacugcaagg cacgcugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8138
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8138
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ugauccugaa ggccaacgcc      120

aucaccacca uccugaccgc cgugaccuuc ugcuucgcca gcggccagaa caucaccgag      180

gaguucuacc agagcaccug cagcgccgug agcaagggcu accugggcgc ccugagaacc      240

ggcugguaca ccagcgugau caccaucgag cugagcaaca ucaaggagau caagugcaac      300

ggcaccgacg ccaaggugaa gcugaucaag caggagcugg acaaguacaa gaacgccgug      360

accgaccugc agcugcugau gcagagcacc cccgccaccg gcagcggcag cgccaucgcc      420

agcggcgugg ccgugugcaa ggugcugcac cuggagggcg aggugaacaa gaucaagagc      480

gcccugcuga gcaccaacaa ggccguggug agccugagcg gcugcggcgu gagcgugcug      540

accuucaagg ugcuggaccu gaagaacuac aucgacaagc agcugcugcc cauccugaac      600

aagcagagcu gcagcauccc caacaucgag accgugaucg aguuccagca gaagaacaac      660

agacugcugg agaucaccag agaguucagc gugaacgccg gcgugaccac ccccgugagc      720

accuacaugc ugaccaacag cgagcugcug agccugauca acgacaugcc caucaccaac      780

gaccagaaga agcugaugag caacaacgug cagaucguga gacagcagag cuacagcauc      840

augugcauca ucaaggagga ggugcuggcc uacguggugc agcugccccu guacggcgug      900

aucgacaccc ccugcuggaa gcugcacacc agcccccugu gcaccaccaa caccaaggag      960

ggcagcaaca ucugccugac cagaaccgac agaggcuggu acugcgacaa cgccggcagc     1020

gugagcuucu ucccccaggc cgagaccugc aaggugcaga gcaacagagu guucugcgac     1080

accaugaaca gccugacccu gcccagcgag gugaaccugu gcaacgugga caucuucaac     1140

cccaaguacg acugcaagau caugaccagc aagaccgacg ugagcagcag cgugaucacc     1200

agccugggcg ccaucgugag cugcuacggc aagaccaagu gcaccgccag caacaagugc     1260

agaggcauca ucaagaccuu cagcaacggc ugcgacuacg ugagcaacaa gggcguggac     1320

accgugagcg ugggcaacac ccuguacuac gugaacaagc aggagggcca gagccuguac     1380

gugaagggcg agcccaucau caacuucuac gacccccugg uguuccccag cgacgaguuc     1440

gacgccagca ucagccaggu gaacgagaag aucaaccaga gccuggccuu caucagaaag     1500

agcgacgagc ugcugcacaa cgugaacgcc ggcaagagca ccaccaacau caugaucacc     1560

accaucauca ucgugaucau cgugauccug cugagccuga ucgccguggg ccugcugcug     1620

uacugcaagg ccagaugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8139
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8139
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagcugc ucauccugaa ggccaacgcu      120

auuaccacaa uccuuacggc cgugaccuuc ugcuuugcga gcggccagaa uauuacagaa      180

gaguucuacc aauccaccug uucugcuguc agcaaagggu aucugggagc ccucagaaca      240

ggcugguaca ccuccguuau cacaauugaa cugucuaaca ucaaggagau caaaugcaau      300

gggaccgacg ccaaggugaa acuuauuaag caggaacugg auaaguauaa aaacgcugug      360

acggaccucc agcugcugau gcagagcacc cccgccacag gauccggcuc ugcuaucgcc      420

agcggggucg cgguguguaa gguucuccac cuggagggag aggugaauaa aauuaagucc      480

gcccuucuga gcaccaacaa agcugucgug ucucucuccg gcugcggcgu uagcgugcug      540

acauuuaagg uccuugaucu gaagaauuac aucgacaaac aacuccugcc uauucugaac      600

aagcagucuu guuccauccc gaauauugaa accgugaucg aguuccagca gaaaaacaau      660

cggcuccugg aaaucacgcg cgaguuuagc gugaacgccg gggucacaac ccccguuucu      720

acauauaugc uuaccaauuc cgagcugcuc agccugauua acgauaugcc uaucaccaau      780

gaccaaaaga aacuuauguc caacaacgug cagauuguga gacagcaguc uuacagcauc      840

augugcauua ucaaggaaga gguccuggcu uaugugguuc aacucccccu guacggagug      900

aucgauacac cuuguuggaa acugcauacg agcccccucu gcaccacaaa uaccaaggaa      960

ggcagcaaca uuugucugac acggaccgac cgcggguggu acugcgauaa ugccggaucu     1020

gucuccuucu uuccucaggc ggagacgugu aaggugcaga gcaacagagu uuucugcgac     1080

acaaugaacu cucuuacccu gccgagcgaa gugaaucucu gcaaugucga uaucuuuaac     1140

cccaaauaug acuguaagau uaugaccucc aaaacagaug ugucuagcuc cgucaucacc     1200

agccugggcg ccauuguguc uugcuacggg aagacaaaau guacggcuuc caauaagugc     1260

cggggaauca ucaagaccuu cagcaacggc ugugacuaug uuucuaauaa aggcguggac     1320

acagucuccg uggggaacac ccuuuacuau guuaauaagc aagagggaca gagccuguac     1380

gugaaaggcg agccuauuau caacuuuuau gauccccucg ucuucccuuc cgacgaauuu     1440

gaugccucua uuagccaggu gaaugagaag aucaaccagu cccuggcuuu cauucgcaaa     1500

ucugacgaac ugcuccacaa cgugaaugcc gggaagucca caaccaacau caugauuacg     1560

accaucauca uuguuaucau ugucauccug cuuucccuga uugccguggg acuccugcug     1620

uacugcaagg cuagaugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8140
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8140
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacuac ucauauugaa agccaacgca      120

aucacaacaa uacuaaccgc cguaacauuu ugcuucgcgu caggccaaaa uauaacagaa      180

gaauuuuacc aaucaacaug cuccgccgua ucaaaaggau accuaggugc auuacgaacc      240

gguugguaca caucaguaau cacaauagaa cuuuccaaca uuaaagaaau aaaaugcaau      300

ggcacagacg caaaagucaa acuaauaaaa caagaacuag acaaauauaa aaacgccguc      360

acagacuuac aacuauuaau gcaaagcaca ccagcaacag gauccggauc agcaauagca      420

ucaggaguag ccgucuguaa aguacuacac cuagaaggcg aaguuaauaa aauuaaauca      480

gcuuuauuau caaccaacaa agcaguagua ucacuauccg gaugcggagu cuccguccua      540

acauucaaag uacuagaccu caagaauuac auagauaaac aacuacuacc aauacucaac      600

aaacaaucau guucaauacc aaacaucgaa accgucauag aauuucaaca aaaaaauaau      660

agacucuuag aaauaacacg agaauuuagc guaaacgcag gagucacaac cccugucuca      720

acauacaugc uaaccaauuc cgaauuauua ucacucauaa augacaugcc aauaacuaau      780

gaccaaaaaa aacuuauguc aaacaacgua caaauaguaa gacaacaauc auauucaaua      840

augugcauaa ucaaagaaga aguuuuagca uauguaguac aacuaccacu auauggcguc      900

auagacacac caugcuggaa auuacacaca ucaccucuau gcacaacaaa cacaaaagaa      960

ggaagcaaca uuugccuaac cagaaccgau agaggauggu acugcgauaa cgcaggcuca     1020

guaucauucu ucccucaagc cgaaacuugc aaaguccaau caaauagagu cuucugcgau     1080

acaaugaacu ccuuaacuuu accaucagaa guaaaucuau gcaacguaga uaucuuuaau     1140

ccaaaauacg auugcaaaau caugacauca aaaacagaug uaucaucuag uguaauuacc     1200

ucccuaggag caauaguaag cugcuacgga aaaacaaaau gcaccgccuc uaacaaaugu     1260

cguggaauaa uaaaaacauu cucaaacgga ugcgauuaug uaucaaauaa aggugucgac     1320

accguaucag uaggcaauac acuauacuau guaaauaaac aagaaggaca aucacucuac     1380

gucaaaggug aaccaauaau aaacuucuac gacccacuug uauucccaag cgacgaauuu     1440

gacgcaucaa uaagccaagu aaacgaaaaa auaaaccaau cacuagcauu caucagaaaa     1500

ucagacgaac uacuccacaa uguaaaugca ggaaaaucaa caaccaauau caugauaaca     1560

accauaauaa uagucauaau aguaauacua uuaucccuca uagccguugg acuacuccua     1620

uauuguaaag cacgauaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8141
<211>  1913
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8141
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaacucc ucauccucaa agccaacgcc      120

aucaccacca uacucaccgc aguaaccuuc ugcuucgcau ccggccaaaa caucacagaa      180

gaguucuacc agaguaccug cuccgccguc uccaaaggcu accuuggcgc ccuccguacc      240

gggugguaca cauccgucau cacaaucgaa cucuccaaca ucaaagaaau aaagugcaac      300

ggcacagacg ccaaaguaaa acugauaaag caagaacucg acaaauacaa aaacgccgua      360

accgaccucc agcuacuaau gcaauccacu cccgccaccg gcagcggauc cgccaucgcc      420

uccggaguag ccgucuguaa agucuuacac cucgaaggcg aagugaacaa aaucaaaucc      480

gcccuacucu caaccaacaa agccguagua ucacucuccg ggugcggcgu uucagugcua      540

acguucaaag uccuugaccu caaaaacuac aucgacaaac aacuccuccc cauccuaaau      600

aaacaauccu gcuccauacc caacaucgag acugucaucg aguuccagca gaaaaacaac      660

cgacuccucg aaaucacacg cgaguucucu gucaacgccg gcgucacaac ccccgucucc      720

acauacaugc ucaccaacag cgaacuccuc ucccuaauca augacaugcc caucaccaac      780

gaccaaaaga aacucauguc aaacaacguc caaaucgucc gccaacaauc cuacagcauc      840

augugcauca ucaaagaaga aguucucgca uacguaguac aacucccccu cuacggagug      900

aucgacaccc ccugcuggaa acuacacacc agcccgcuuu gcaccacaaa caccaaggaa      960

ggcuccaaca ucugccucac ucgaaccgac cgcggcuggu acugcgacaa cgcaggcucc     1020

gucaguuucu uuccccaagc agaaacaugc aaaguccaau ccaaccgagu auucugcgac     1080

accaugaacu cccucacccu accauccgaa guuaaccuau gcaacgugga caucuucaac     1140

cccaaguacg acugcaaaau uaugaccucc aaaaccgacg uauccuccag cgucaucacc     1200

agccucggag caauagucuc cugcuacggc aagaccaagu gcaccgcuuc caacaagugu     1260

cgcggaauca ucaaaaccuu cucaaacggc ugcgacuacg ucuccaacaa aggcgucgac     1320

accguauccg uaggaaacac ccuauacuac gucaacaaac aagaaggaca aucccucuau     1380

gucaaaggcg aacccaucau caauuucuac gacccccuag ucuucccuuc cgacgaguuc     1440

gacgcgucca ucagccaagu caaugaaaag aucaaccaga gccuggcauu cauccgcaaa     1500

uccgacgaac uccuccacaa cgucaacgcg ggaaaaucca cgacaaacau caugaucacc     1560

accaucauca ucgucaucau agucauucuc cuuucucuca ucgccguggg acuacuucuc     1620

uacugcaaag cccgauaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac     1680

ucagcuaugg ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau     1740

guuaugaaau gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1860

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1913


<210>  8142
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8142
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8143
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

ggugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8144
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8145
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8145
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8146
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8146
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8147
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8147
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8148
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8148
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauugaaagc caacgcaauc acaacaauac      120

uaaccgccgu aacauuuugc uucgcgucag gccaaaauau aacagaagaa uuuuaccaau      180

caacaugcuc cgccguauca aaaggauacc uaggugcauu acgaaccggu ugguacacau      240

caguaaucac aauagaacuu uccaacauua aagaaauaaa augcaauggc acagacgcaa      300

aagucaaacu aauaaaacaa gaacuagaca aauauaaaaa cgccgucaca gacuuacaac      360

uauuaaugca aagcacacca gcaacaggau ccggaucagc aauagcauca ggaguagccg      420

ucuguaaagu acuacaccua gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa      480

ccaacaaagc aguaguauca cuauccggau gcggagucuc cguccuaaca uucaaaguac      540

uagaccucaa gaauuacaua gauaaacaac uacuaccaau acucaacaaa caaucauguu      600

caauaccaaa caucgaaacc gucauagaau uucaacaaaa aaauaauaga cucuuagaaa      660

uaacacgaga auuuagcgua aacgcaggag ucacaacccc ugucucaaca uacaugcuaa      720

ccaauuccga auuauuauca cucauaaaug acaugccaau aacuaaugac caaaaaaaac      780

uuaugucaaa caacguacaa auaguaagac aacaaucaua uucaauaaug ugcauaauca      840

aagaagaagu uuuagcauau guaguacaac uaccacuaua uggcgucaua gacacaccau      900

gcuggaaauu acacacauca ccucuaugca caacaaacac aaaagaagga agcaacauuu      960

gccuaaccag aaccgauaga ggaugguacu gcgauaacgc aggcucagua ucauucuucc     1020

cucaagccga aacuugcaaa guccaaucaa auagagucuu cugcgauaca augaacuccu     1080

uaacuuuacc aucagaagua aaucuaugca acguagauau cuuuaaucca aaauacgauu     1140

gcaaaaucau gacaucaaaa acagauguau caucuagugu aauuaccucc cuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa     1260

aaacauucuc aaacggaugc gauuauguau caaauaaagg ugucgacacc guaucaguag     1320

gcaauacacu auacuaugua aauaaacaag aaggacaauc acucuacguc aaaggugaac     1380

caauaauaaa cuucuacgac ccacuuguau ucccaagcga cgaauuugac gcaucaauaa     1440

gccaaguaaa cgaaaaaaua aaccaaucac uagcauucau cagaaaauca gacgaacuac     1500

uccacaaugu aaaugcagga aaaucaacaa ccaauaucau gauaacaacc auaauaauag     1560

ucauaauagu aauacuauua ucccucauag ccguuggacu acuccuauau uguaaagcac     1620

gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8149
<211>  1904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8149
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccauc accaccauac      120

ucaccgcagu aaccuucugc uucgcauccg gccaaaacau cacagaagag uucuaccaga      180

guaccugcuc cgccgucucc aaaggcuacc uuggcgcccu ccguaccggg ugguacacau      240

ccgucaucac aaucgaacuc uccaacauca aagaaauaaa gugcaacggc acagacgcca      300

aaguaaaacu gauaaagcaa gaacucgaca aauacaaaaa cgccguaacc gaccuccagc      360

uacuaaugca auccacuccc gccaccggca gcggauccgc caucgccucc ggaguagccg      420

ucuguaaagu cuuacaccuc gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc cguaguauca cucuccgggu gcggcguuuc agugcuaacg uucaaagucc      540

uugaccucaa aaacuacauc gacaaacaac uccuccccau ccuaaauaaa caauccugcu      600

ccauacccaa caucgagacu gucaucgagu uccagcagaa aaacaaccga cuccucgaaa      660

ucacacgcga guucucuguc aacgccggcg ucacaacccc cgucuccaca uacaugcuca      720

ccaacagcga acuccucucc cuaaucaaug acaugcccau caccaacgac caaaagaaac      780

ucaugucaaa caacguccaa aucguccgcc aacaauccua cagcaucaug ugcaucauca      840

aagaagaagu ucucgcauac guaguacaac ucccccucua cggagugauc gacacccccu      900

gcuggaaacu acacaccagc ccgcuuugca ccacaaacac caaggaaggc uccaacaucu      960

gccucacucg aaccgaccgc ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc     1020

cccaagcaga aacaugcaaa guccaaucca accgaguauu cugcgacacc augaacuccc     1080

ucacccuacc auccgaaguu aaccuaugca acguggacau cuucaacccc aaguacgacu     1140

gcaaaauuau gaccuccaaa accgacguau ccuccagcgu caucaccagc cucggagcaa     1200

uagucuccug cuacggcaag accaagugca ccgcuuccaa caagugucgc ggaaucauca     1260

aaaccuucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacacc guauccguag     1320

gaaacacccu auacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccaucaucaa uuucuacgac ccccuagucu ucccuuccga cgaguucgac gcguccauca     1440

gccaagucaa ugaaaagauc aaccagagcc uggcauucau ccgcaaaucc gacgaacucc     1500

uccacaacgu caacgcggga aaauccacga caaacaucau gaucaccacc aucaucaucg     1560

ucaucauagu cauucuccuu ucucucaucg ccgugggacu acuucucuac ugcaaagccc     1620

gauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu cucccaggau     1680

ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc augacuuacc     1740

ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1860

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1904


<210>  8150
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8150
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca guccaccccg gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg      420

ugugcaaggu gcugcaccuc gagggggagg ucaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggugagc cucuccggcu gcggcgucag cgugcugacc uucaaggugc      540

uggaccucaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugcu      600

ccauccccaa caucgagacg gugaucgagu uccagcagaa gaacaaccgg cuccuggaga      660

ucacccgcga guucagcgug aacgccgggg ucaccacccc cguguccacg uacaugcuga      720

ccaacagcga gcuccugucc cugaucaacg acaugccgau caccaacgac cagaagaagc      780

ucaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggcguac gugguccagc ugccccucua cggcgugauc gacacccccu      900

gcuggaagcu gcacacgagc ccccugugca ccaccaacac caaggagggg uccaacaucu      960

gccucacgcg caccgaccgg ggcugguacu gcgacaacgc cggcagcguc uccuucuucc     1020

cgcaggccga gaccugcaag gugcagagca accgcguguu cugcgacacc augaacuccc     1080

ugacgcugcc cagcgaggua aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacguga gcuccagcgu gaucaccucc cugggggcca     1200

ucgucagcug cuacggcaag acgaagugca ccgccagcaa caagugccgg gggaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg cguggacacc guguccgucg     1320

ggaacacccu guacuacgug aacaagcagg agggccagag ccucuacgug aagggggagc     1380

ccaucaucaa cuucuacgac ccgcuggucu uccccuccga cgaguucgac gcgagcaucu     1440

cccaggugaa cgagaagauc aaccagagcc uggccuucau ccgcaagucc gacgagcugc     1500

uccacaacgu gaacgccggc aagagcacga ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu gauccugcug ucccucaucg ccguggggcu gcugcucuac ugcaaggccc     1620

ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8151
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8151
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucggcgcccu gcgcaccggg ugguacacca      240

gcgugaucac caucgagcug uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gaccugcagc      360

uccugaugca gagcaccccc gccaccgggu ccggcagcgc caucgccucc ggcguggcgg      420

ugugcaaggu ccugcaccuc gagggggagg ugaacaagau caagagcgcc cugcugucca      480

ccaacaaggc cguggucagc cucuccggcu gcggggugag cgugcugacg uucaaggucc      540

uggaccucaa gaacuacauc gacaagcagc ugcugccgau ccucaacaag caguccugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaaccgg cugcuggaga      660

ucacccgcga guucuccgug aacgccggcg ucaccacgcc cgugagcacc uacaugcuca      720

ccaacuccga gcugcugagc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucguccggc agcaguccua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac gugguccagc ucccgcugua cggggugauc gacacgcccu      900

gcuggaagcu gcacaccagc ccccucugca ccaccaacac gaaggagggc uccaacaucu      960

gccugacccg caccgaccgg ggcugguacu gcgacaacgc gggguccgug agcuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcguguu cugcgacacg augaacagcc     1080

ugacccuccc guccgagguc aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacgugu ccagcuccgu caucacgagc cugggcgcca     1200

ucguguccug cuacgggaag accaagugca ccgccagcaa caagugccgg ggcaucauca     1260

agaccuucuc caacggcugc gacuacguga gcaacaaggg ggucgacacg guguccgugg     1320

gcaacacccu cuacuacguc aacaagcagg aggggcagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu ucccgagcga cgaguucgac gccuccauca     1440

gccaggucaa cgagaagauc aaccaguccc ucgcguucau ccgcaagagc gacgagcugc     1500

ugcacaacgu gaacgccggg aaguccacca ccaacaucau gaucaccacg aucaucaucg     1560

ugaucaucgu cauccuccug agccugaucg ccgugggccu ccugcuguac ugcaaggccc     1620

ggugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8152
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8152
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcuccuca uccucaaggc caacgccauc accaccaucc      120

ucaccgccgu caccuucugc uucgccuccg gccagaacau caccgaggag uucuaccagu      180

ccaccugcuc cgccgucucc aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu      240

ccgucaucac caucgagcuc uccaacauca aggagaucaa gugcaacggc accgacgcca      300

aggucaagcu caucaagcag gagcucgaca aguacaagaa cgccgucacc gaccuccagc      360

uccucaugca guccaccccc gccaccggcu ccggcuccgc caucgccucc ggcgucgccg      420

ucugcaaggu ccuccaccuc gagggcgagg ucaacaagau caaguccgcc cuccucucca      480

ccaacaaggc cgucgucucc cucuccggcu gcggcgucuc cguccucacc uucaaggucc      540

ucgaccucaa gaacuacauc gacaagcagc uccuccccau ccucaacaag caguccugcu      600

ccauccccaa caucgagacc gucaucgagu uccagcagaa gaacaaccgc cuccucgaga      660

ucacccgcga guucuccguc aacgccggcg ucaccacccc cgucuccacc uacaugcuca      720

ccaacuccga gcuccucucc cucaucaacg acaugcccau caccaacgac cagaagaagc      780

ucauguccaa caacguccag aucguccgcc agcaguccua cuccaucaug ugcaucauca      840

aggaggaggu ccucgccuac gucguccagc ucccccucua cggcgucauc gacacccccu      900

gcuggaagcu ccacaccucc ccccucugca ccaccaacac caaggagggc uccaacaucu      960

gccucacccg caccgaccgc ggcugguacu gcgacaacgc cggcuccguc uccuucuucc     1020

cccaggccga gaccugcaag guccagucca accgcgucuu cugcgacacc augaacuccc     1080

ucacccuccc cuccgagguc aaccucugca acgucgacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccuccaag accgacgucu ccuccuccgu caucaccucc cucggcgcca     1200

ucgucuccug cuacggcaag accaagugca ccgccuccaa caagugccgc ggcaucauca     1260

agaccuucuc caacggcugc gacuacgucu ccaacaaggg cgucgacacc gucuccgucg     1320

gcaacacccu cuacuacguc aacaagcagg agggccaguc ccucuacguc aagggcgagc     1380

ccaucaucaa cuucuacgac ccccucgucu uccccuccga cgaguucgac gccuccaucu     1440

cccaggucaa cgagaagauc aaccaguccc ucgccuucau ccgcaagucc gacgagcucc     1500

uccacaacgu caacgccggc aaguccacca ccaacaucau gaucaccacc aucaucaucg     1560

ucaucaucgu cauccuccuc ucccucaucg ccgucggccu ccuccucuac ugcaaggccc     1620

gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8153
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8153
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccuuaaggc caacgcuauu accacaauac      120

ugacugcagu gacguucugc uuugccagcg gccagaauau caccgaagag uucuaccaau      180

ccacauguuc ugcggucuca aaaggguauu ugggagcuuu aagaacuggu ugguacacca      240

guguuauuac aaucgaacug agcaacauua aggagaucaa augcaauggc accgacgcca      300

aggugaaacu aauaaagcag gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc      360

uucugaugca guccacaccc gccaccgggu cuggaucggc uaucgcauca ggcguggccg      420

ucuguaaggu guugcaccuc gagggugagg uuaauaaaau uaagagcgcu cugcugagua      480

cgaacaaagc cguggucucc cucucugggu gcggagugag cguauuaacu uuuaagguuc      540

uggaucuuaa gaauuacauc gacaaacaau ugcugccuau ucuaaacaag caguccuguu      600

caaucccaaa uauagaaacc gugauugagu uccagcagaa aaacaauagg cuccuggaaa      660

ucacacggga guuuaguguc aacgcgggcg ugacuacccc ggugagcaca uauaugcuua      720

ccaauucuga gcuguugucc cucauuaacg auaugcccau cacgaaugac caaaagaaac      780

ugaugucaaa caacguccag aucguucgcc agcagagcua caguauuaug ugcauaauca      840

aggaagaggu guuagcauau guagugcaac ugccucucua cggcgucauu gauacuccau      900

guuggaaacu ucauacaucu ccccugugca ccacuaauac aaaggaaggg uccaacaucu      960

guuugacccg aacggaccgu ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc     1020

cucaggcuga gaccuguaag guucagucua acagaguguu cugcgacaca augaacuccc     1080

uaacucugcc aucagaaguc aaucucugca auguggauau auuuaacccc aaauaugacu     1140

guaagauuau gaccaguaaa acagauguaa gcuccucugu uaucacuagc cugggcgcca     1200

ucgugucaug cuacgggaag accaaaugua cagcaaguaa uaagugcagg ggaauuauca     1260

agaccuucuc caacggcugu gacuauguca gcaauaaagg uguggacacu gucucugugg     1320

ggaacacgcu uuacuauguu aauaagcaag agggacaguc acuguacgug aaaggcgagc     1380

cuauuauaaa cuuuuaugau ccauugguau ucccgaguga cgaauuugau gcuagcaucu     1440

cccaggucaa ugagaagauu aaccagucuc ucgccuucau ccggaaaucg gacgaacugu     1500

uacacaacgu gaaugcgggc aagagcacaa ccaacaucau gauuacuacc auaaucauug     1560

uuaucauugu gauccugcua ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac     1620

gcugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8154
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8154
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuga uccugaaggc caacgccauc accaccaucc      120

ugaccgccgu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccaga      180

gcaccugcag cgccgugagc aagggcuacc ugggcgcccu gagaaccggc ugguacacca      240

gcgugaucac caucgagcug agcaacauca aggagaucaa gugcaacggc accgacgcca      300

aggugaagcu gaucaagcag gagcuggaca aguacaagaa cgccgugacc gaccugcagc      360

ugcugaugca gagcaccccc gccaccggca gcggcagcgc caucgccagc ggcguggccg      420

ugugcaaggu gcugcaccug gagggcgagg ugaacaagau caagagcgcc cugcugagca      480

ccaacaaggc cguggugagc cugagcggcu gcggcgugag cgugcugacc uucaaggugc      540

uggaccugaa gaacuacauc gacaagcagc ugcugcccau ccugaacaag cagagcugca      600

gcauccccaa caucgagacc gugaucgagu uccagcagaa gaacaacaga cugcuggaga      660

ucaccagaga guucagcgug aacgccggcg ugaccacccc cgugagcacc uacaugcuga      720

ccaacagcga gcugcugagc cugaucaacg acaugcccau caccaacgac cagaagaagc      780

ugaugagcaa caacgugcag aucgugagac agcagagcua cagcaucaug ugcaucauca      840

aggaggaggu gcuggccuac guggugcagc ugccccugua cggcgugauc gacacccccu      900

gcuggaagcu gcacaccagc ccccugugca ccaccaacac caaggagggc agcaacaucu      960

gccugaccag aaccgacaga ggcugguacu gcgacaacgc cggcagcgug agcuucuucc     1020

cccaggccga gaccugcaag gugcagagca acagaguguu cugcgacacc augaacagcc     1080

ugacccugcc cagcgaggug aaccugugca acguggacau cuucaacccc aaguacgacu     1140

gcaagaucau gaccagcaag accgacguga gcagcagcgu gaucaccagc cugggcgcca     1200

ucgugagcug cuacggcaag accaagugca ccgccagcaa caagugcaga ggcaucauca     1260

agaccuucag caacggcugc gacuacguga gcaacaaggg cguggacacc gugagcgugg     1320

gcaacacccu guacuacgug aacaagcagg agggccagag ccuguacgug aagggcgagc     1380

ccaucaucaa cuucuacgac ccccuggugu uccccagcga cgaguucgac gccagcauca     1440

gccaggugaa cgagaagauc aaccagagcc uggccuucau cagaaagagc gacgagcugc     1500

ugcacaacgu gaacgccggc aagagcacca ccaacaucau gaucaccacc aucaucaucg     1560

ugaucaucgu gauccugcug agccugaucg ccgugggccu gcugcuguac ugcaaggcca     1620

gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8155
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8155
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgcuauu accacaaucc      120

uuacggccgu gaccuucugc uuugcgagcg gccagaauau uacagaagag uucuaccaau      180

ccaccuguuc ugcugucagc aaaggguauc ugggagcccu cagaacaggc ugguacaccu      240

ccguuaucac aauugaacug ucuaacauca aggagaucaa augcaauggg accgacgcca      300

aggugaaacu uauuaagcag gaacuggaua aguauaaaaa cgcugugacg gaccuccagc      360

ugcugaugca gagcaccccc gccacaggau ccggcucugc uaucgccagc ggggucgcgg      420

uguguaaggu ucuccaccug gagggagagg ugaauaaaau uaaguccgcc cuucugagca      480

ccaacaaagc ugucgugucu cucuccggcu gcggcguuag cgugcugaca uuuaaggucc      540

uugaucugaa gaauuacauc gacaaacaac uccugccuau ucugaacaag cagucuuguu      600

ccaucccgaa uauugaaacc gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa      660

ucacgcgcga guuuagcgug aacgccgggg ucacaacccc cguuucuaca uauaugcuua      720

ccaauuccga gcugcucagc cugauuaacg auaugccuau caccaaugac caaaagaaac      780

uuauguccaa caacgugcag auugugagac agcagucuua cagcaucaug ugcauuauca      840

aggaagaggu ccuggcuuau gugguucaac ucccccugua cggagugauc gauacaccuu      900

guuggaaacu gcauacgagc ccccucugca ccacaaauac caaggaaggc agcaacauuu      960

gucugacacg gaccgaccgc gggugguacu gcgauaaugc cggaucuguc uccuucuuuc     1020

cucaggcgga gacguguaag gugcagagca acagaguuuu cugcgacaca augaacucuc     1080

uuacccugcc gagcgaagug aaucucugca augucgauau cuuuaacccc aaauaugacu     1140

guaagauuau gaccuccaaa acagaugugu cuagcuccgu caucaccagc cugggcgcca     1200

uugugucuug cuacgggaag acaaaaugua cggcuuccaa uaagugccgg ggaaucauca     1260

agaccuucag caacggcugu gacuauguuu cuaauaaagg cguggacaca gucuccgugg     1320

ggaacacccu uuacuauguu aauaagcaag agggacagag ccuguacgug aaaggcgagc     1380

cuauuaucaa cuuuuaugau ccccucgucu ucccuuccga cgaauuugau gccucuauua     1440

gccaggugaa ugagaagauc aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc     1500

uccacaacgu gaaugccggg aaguccacaa ccaacaucau gauuacgacc aucaucauug     1560

uuaucauugu cauccugcuu ucccugauug ccgugggacu ccugcuguac ugcaaggcua     1620

gaugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8156
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8156
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuacuca uauugaaagc caacgcaauc acaacaauac      120

uaaccgccgu aacauuuugc uucgcgucag gccaaaauau aacagaagaa uuuuaccaau      180

caacaugcuc cgccguauca aaaggauacc uaggugcauu acgaaccggu ugguacacau      240

caguaaucac aauagaacuu uccaacauua aagaaauaaa augcaauggc acagacgcaa      300

aagucaaacu aauaaaacaa gaacuagaca aauauaaaaa cgccgucaca gacuuacaac      360

uauuaaugca aagcacacca gcaacaggau ccggaucagc aauagcauca ggaguagccg      420

ucuguaaagu acuacaccua gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa      480

ccaacaaagc aguaguauca cuauccggau gcggagucuc cguccuaaca uucaaaguac      540

uagaccucaa gaauuacaua gauaaacaac uacuaccaau acucaacaaa caaucauguu      600

caauaccaaa caucgaaacc gucauagaau uucaacaaaa aaauaauaga cucuuagaaa      660

uaacacgaga auuuagcgua aacgcaggag ucacaacccc ugucucaaca uacaugcuaa      720

ccaauuccga auuauuauca cucauaaaug acaugccaau aacuaaugac caaaaaaaac      780

uuaugucaaa caacguacaa auaguaagac aacaaucaua uucaauaaug ugcauaauca      840

aagaagaagu uuuagcauau guaguacaac uaccacuaua uggcgucaua gacacaccau      900

gcuggaaauu acacacauca ccucuaugca caacaaacac aaaagaagga agcaacauuu      960

gccuaaccag aaccgauaga ggaugguacu gcgauaacgc aggcucagua ucauucuucc     1020

cucaagccga aacuugcaaa guccaaucaa auagagucuu cugcgauaca augaacuccu     1080

uaacuuuacc aucagaagua aaucuaugca acguagauau cuuuaaucca aaauacgauu     1140

gcaaaaucau gacaucaaaa acagauguau caucuagugu aauuaccucc cuaggagcaa     1200

uaguaagcug cuacggaaaa acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa     1260

aaacauucuc aaacggaugc gauuauguau caaauaaagg ugucgacacc guaucaguag     1320

gcaauacacu auacuaugua aauaaacaag aaggacaauc acucuacguc aaaggugaac     1380

caauaauaaa cuucuacgac ccacuuguau ucccaagcga cgaauuugac gcaucaauaa     1440

gccaaguaaa cgaaaaaaua aaccaaucac uagcauucau cagaaaauca gacgaacuac     1500

uccacaaugu aaaugcagga aaaucaacaa ccaauaucau gauaacaacc auaauaauag     1560

ucauaauagu aauacuauua ucccucauag ccguuggacu acuccuauau uguaaagcac     1620

gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8157
<211>  2120
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8157
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaacuccuca uccucaaagc caacgccauc accaccauac      120

ucaccgcagu aaccuucugc uucgcauccg gccaaaacau cacagaagag uucuaccaga      180

guaccugcuc cgccgucucc aaaggcuacc uuggcgcccu ccguaccggg ugguacacau      240

ccgucaucac aaucgaacuc uccaacauca aagaaauaaa gugcaacggc acagacgcca      300

aaguaaaacu gauaaagcaa gaacucgaca aauacaaaaa cgccguaacc gaccuccagc      360

uacuaaugca auccacuccc gccaccggca gcggauccgc caucgccucc ggaguagccg      420

ucuguaaagu cuuacaccuc gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa      480

ccaacaaagc cguaguauca cucuccgggu gcggcguuuc agugcuaacg uucaaagucc      540

uugaccucaa aaacuacauc gacaaacaac uccuccccau ccuaaauaaa caauccugcu      600

ccauacccaa caucgagacu gucaucgagu uccagcagaa aaacaaccga cuccucgaaa      660

ucacacgcga guucucuguc aacgccggcg ucacaacccc cgucuccaca uacaugcuca      720

ccaacagcga acuccucucc cuaaucaaug acaugcccau caccaacgac caaaagaaac      780

ucaugucaaa caacguccaa aucguccgcc aacaauccua cagcaucaug ugcaucauca      840

aagaagaagu ucucgcauac guaguacaac ucccccucua cggagugauc gacacccccu      900

gcuggaaacu acacaccagc ccgcuuugca ccacaaacac caaggaaggc uccaacaucu      960

gccucacucg aaccgaccgc ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc     1020

cccaagcaga aacaugcaaa guccaaucca accgaguauu cugcgacacc augaacuccc     1080

ucacccuacc auccgaaguu aaccuaugca acguggacau cuucaacccc aaguacgacu     1140

gcaaaauuau gaccuccaaa accgacguau ccuccagcgu caucaccagc cucggagcaa     1200

uagucuccug cuacggcaag accaagugca ccgcuuccaa caagugucgc ggaaucauca     1260

aaaccuucuc aaacggcugc gacuacgucu ccaacaaagg cgucgacacc guauccguag     1320

gaaacacccu auacuacguc aacaaacaag aaggacaauc ccucuauguc aaaggcgaac     1380

ccaucaucaa uuucuacgac ccccuagucu ucccuuccga cgaguucgac gcguccauca     1440

gccaagucaa ugaaaagauc aaccagagcc uggcauucau ccgcaaaucc gacgaacucc     1500

uccacaacgu caacgcggga aaauccacga caaacaucau gaucaccacc aucaucaucg     1560

ucaucauagu cauucuccuu ucucucaucg ccgugggacu acuucucuac ugcaaagccc     1620

gauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca auuaauuaag     1680

agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc aacaccgcaa     1740

ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu ugcuuagaug     1800

uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa     1860

guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag aaauaaauga     1920

aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa     1980

ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     2100

uuuucagagc caccagaauu                                                 2120


<210>  8158
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8158
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8159
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8159
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccggugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8160
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8160
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8161
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8161
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8162
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8162
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8163
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8163
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaugagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8164
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8164
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauugaaa gccaacgcaa ucacaacaau acuaaccgcc      120

guaacauuuu gcuucgcguc aggccaaaau auaacagaag aauuuuacca aucaacaugc      180

uccgccguau caaaaggaua ccuaggugca uuacgaaccg guugguacac aucaguaauc      240

acaauagaac uuuccaacau uaaagaaaua aaaugcaaug gcacagacgc aaaagucaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgccguca cagacuuaca acuauuaaug      360

caaagcacac cagcaacagg auccggauca gcaauagcau caggaguagc cgucuguaaa      420

guacuacacc uagaaggcga aguuaauaaa auuaaaucag cuuuauuauc aaccaacaaa      480

gcaguaguau cacuauccgg augcggaguc uccguccuaa cauucaaagu acuagaccuc      540

aagaauuaca uagauaaaca acuacuacca auacucaaca aacaaucaug uucaauacca      600

aacaucgaaa ccgucauaga auuucaacaa aaaaauaaua gacucuuaga aauaacacga      660

gaauuuagcg uaaacgcagg agucacaacc ccugucucaa cauacaugcu aaccaauucc      720

gaauuauuau cacucauaaa ugacaugcca auaacuaaug accaaaaaaa acuuauguca      780

aacaacguac aaauaguaag acaacaauca uauucaauaa ugugcauaau caaagaagaa      840

guuuuagcau auguaguaca acuaccacua uauggcguca uagacacacc augcuggaaa      900

uuacacacau caccucuaug cacaacaaac acaaaagaag gaagcaacau uugccuaacc      960

agaaccgaua gaggauggua cugcgauaac gcaggcucag uaucauucuu cccucaagcc     1020

gaaacuugca aaguccaauc aaauagaguc uucugcgaua caaugaacuc cuuaacuuua     1080

ccaucagaag uaaaucuaug caacguagau aucuuuaauc caaaauacga uugcaaaauc     1140

augacaucaa aaacagaugu aucaucuagu guaauuaccu cccuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccucu aacaaauguc guggaauaau aaaaacauuc     1260

ucaaacggau gcgauuaugu aucaaauaaa ggugucgaca ccguaucagu aggcaauaca     1320

cuauacuaug uaaauaaaca agaaggacaa ucacucuacg ucaaagguga accaauaaua     1380

aacuucuacg acccacuugu auucccaagc gacgaauuug acgcaucaau aagccaagua     1440

aacgaaaaaa uaaaccaauc acuagcauuc aucagaaaau cagacgaacu acuccacaau     1500

guaaaugcag gaaaaucaac aaccaauauc augauaacaa ccauaauaau agucauaaua     1560

guaauacuau uaucccucau agccguugga cuacuccuau auuguaaagc acgauaagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8165
<211>  1896
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8165
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca ucaccaccau acucaccgca      120

guaaccuucu gcuucgcauc cggccaaaac aucacagaag aguucuacca gaguaccugc      180

uccgccgucu ccaaaggcua ccuuggcgcc cuccguaccg ggugguacac auccgucauc      240

acaaucgaac ucuccaacau caaagaaaua aagugcaacg gcacagacgc caaaguaaaa      300

cugauaaagc aagaacucga caaauacaaa aacgccguaa ccgaccucca gcuacuaaug      360

caauccacuc ccgccaccgg cagcggaucc gccaucgccu ccggaguagc cgucuguaaa      420

gucuuacacc ucgaaggcga agugaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gccguaguau cacucuccgg gugcggcguu ucagugcuaa cguucaaagu ccuugaccuc      540

aaaaacuaca ucgacaaaca acuccucccc auccuaaaua aacaauccug cuccauaccc      600

aacaucgaga cugucaucga guuccagcag aaaaacaacc gacuccucga aaucacacgc      660

gaguucucug ucaacgccgg cgucacaacc cccgucucca cauacaugcu caccaacagc      720

gaacuccucu cccuaaucaa ugacaugccc aucaccaacg accaaaagaa acucauguca      780

aacaacgucc aaaucguccg ccaacaaucc uacagcauca ugugcaucau caaagaagaa      840

guucucgcau acguaguaca acucccccuc uacggaguga ucgacacccc cugcuggaaa      900

cuacacacca gcccgcuuug caccacaaac accaaggaag gcuccaacau cugccucacu      960

cgaaccgacc gcggcuggua cugcgacaac gcaggcuccg ucaguuucuu uccccaagca     1020

gaaacaugca aaguccaauc caaccgagua uucugcgaca ccaugaacuc ccucacccua     1080

ccauccgaag uuaaccuaug caacguggac aucuucaacc ccaaguacga cugcaaaauu     1140

augaccucca aaaccgacgu auccuccagc gucaucacca gccucggagc aauagucucc     1200

ugcuacggca agaccaagug caccgcuucc aacaaguguc gcggaaucau caaaaccuuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca ccguauccgu aggaaacacc     1320

cuauacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccaucauc     1380

aauuucuacg acccccuagu cuucccuucc gacgaguucg acgcguccau cagccaaguc     1440

aaugaaaaga ucaaccagag ccuggcauuc auccgcaaau ccgacgaacu ccuccacaac     1500

gucaacgcgg gaaaauccac gacaaacauc augaucacca ccaucaucau cgucaucaua     1560

gucauucucc uuucucucau cgccguggga cuacuucucu acugcaaagc ccgauaagga     1620

cuaguacugg cugcaucucc cuuuccucug uccuccaucc uucucccagg auggugaagg     1680

gggaccuggu acccagugau ccccacccca ggauccuaaa ucaugacuua ccugcuaaua     1740

aaaacucauu ggaaaaguga gaagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1860

ccccccccaa aggcucuuuu cagagccacc agaauu                               1896


<210>  8166
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8166
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcggaccg gcugguacac cuccgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg ggaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

caguccaccc cggcaaccgg cuccggcucc gccaucgcga gcggcgucgc cgugugcaag      420

gugcugcacc ucgaggggga ggucaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguga gccucuccgg cugcggcguc agcgugcuga ccuucaaggu gcuggaccuc      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cuccaucccc      600

aacaucgaga cggugaucga guuccagcag aagaacaacc ggcuccugga gaucacccgc      660

gaguucagcg ugaacgccgg ggucaccacc cccgugucca cguacaugcu gaccaacagc      720

gagcuccugu cccugaucaa cgacaugccg aucaccaacg accagaagaa gcucaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggcgu acguggucca gcugccccuc uacggcguga ucgacacccc cugcuggaag      900

cugcacacga gcccccugug caccaccaac accaaggagg gguccaacau cugccucacg      960

cgcaccgacc ggggcuggua cugcgacaac gccggcagcg ucuccuucuu cccgcaggcc     1020

gagaccugca aggugcagag caaccgcgug uucugcgaca ccaugaacuc ccugacgcug     1080

cccagcgagg uaaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu gagcuccagc gugaucaccu cccugggggc caucgucagc     1200

ugcuacggca agacgaagug caccgccagc aacaagugcc gggggaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggcguggaca ccguguccgu cgggaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccucuacg ugaaggggga gcccaucauc     1380

aacuucuacg acccgcuggu cuuccccucc gacgaguucg acgcgagcau cucccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc auccgcaagu ccgacgagcu gcuccacaac     1500

gugaacgccg gcaagagcac gaccaacauc augaucacca ccaucaucau cgucaucauc     1560

gugauccugc ugucccucau cgccgugggg cugcugcucu acugcaaggc ccggugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8167
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8167
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcca ucaccaccau ccugacggcg      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca guccacgugc      180

agcgccgucu ccaaggggua ccucggcgcc cugcgcaccg ggugguacac cagcgugauc      240

accaucgagc uguccaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cucaucaagc aggagcugga caaguacaag aacgcgguca cggaccugca gcuccugaug      360

cagagcaccc ccgccaccgg guccggcagc gccaucgccu ccggcguggc ggugugcaag      420

guccugcacc ucgaggggga ggugaacaag aucaagagcg cccugcuguc caccaacaag      480

gccgugguca gccucuccgg cugcggggug agcgugcuga cguucaaggu ccuggaccuc      540

aagaacuaca ucgacaagca gcugcugccg auccucaaca agcaguccug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaacc ggcugcugga gaucacccgc      660

gaguucuccg ugaacgccgg cgucaccacg cccgugagca ccuacaugcu caccaacucc      720

gagcugcuga gccucaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucguccg gcagcagucc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggucca gcucccgcug uacgggguga ucgacacgcc cugcuggaag      900

cugcacacca gcccccucug caccaccaac acgaaggagg gcuccaacau cugccugacc      960

cgcaccgacc ggggcuggua cugcgacaac gcgggguccg ugagcuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcgug uucugcgaca cgaugaacag ccugacccuc     1080

ccguccgagg ucaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu guccagcucc gucaucacga gccugggcgc caucgugucc     1200

ugcuacggga agaccaagug caccgccagc aacaagugcc ggggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu gagcaacaag ggggucgaca cgguguccgu gggcaacacc     1320

cucuacuacg ucaacaagca ggaggggcag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guucccgagc gacgaguucg acgccuccau cagccagguc     1440

aacgagaaga ucaaccaguc ccucgcguuc auccgcaaga gcgacgagcu gcugcacaac     1500

gugaacgccg ggaaguccac caccaacauc augaucacca cgaucaucau cgugaucauc     1560

gucauccucc ugagccugau cgccgugggc cuccugcugu acugcaaggc ccggugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8168
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8168
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcuccu cauccucaag gccaacgcca ucaccaccau ccucaccgcc      120

gucaccuucu gcuucgccuc cggccagaac aucaccgagg aguucuacca guccaccugc      180

uccgccgucu ccaagggcua ccucggcgcc cuccgcaccg gcugguacac cuccgucauc      240

accaucgagc ucuccaacau caaggagauc aagugcaacg gcaccgacgc caaggucaag      300

cucaucaagc aggagcucga caaguacaag aacgccguca ccgaccucca gcuccucaug      360

caguccaccc ccgccaccgg cuccggcucc gccaucgccu ccggcgucgc cgucugcaag      420

guccuccacc ucgagggcga ggucaacaag aucaaguccg cccuccucuc caccaacaag      480

gccgucgucu cccucuccgg cugcggcguc uccguccuca ccuucaaggu ccucgaccuc      540

aagaacuaca ucgacaagca gcuccucccc auccucaaca agcaguccug cuccaucccc      600

aacaucgaga ccgucaucga guuccagcag aagaacaacc gccuccucga gaucacccgc      660

gaguucuccg ucaacgccgg cgucaccacc cccgucucca ccuacaugcu caccaacucc      720

gagcuccucu cccucaucaa cgacaugccc aucaccaacg accagaagaa gcucaugucc      780

aacaacgucc agaucguccg ccagcagucc uacuccauca ugugcaucau caaggaggag      840

guccucgccu acgucgucca gcucccccuc uacggcguca ucgacacccc cugcuggaag      900

cuccacaccu ccccccucug caccaccaac accaaggagg gcuccaacau cugccucacc      960

cgcaccgacc gcggcuggua cugcgacaac gccggcuccg ucuccuucuu cccccaggcc     1020

gagaccugca agguccaguc caaccgcguc uucugcgaca ccaugaacuc ccucacccuc     1080

cccuccgagg ucaaccucug caacgucgac aucuucaacc ccaaguacga cugcaagauc     1140

augaccucca agaccgacgu cuccuccucc gucaucaccu cccucggcgc caucgucucc     1200

ugcuacggca agaccaagug caccgccucc aacaagugcc gcggcaucau caagaccuuc     1260

uccaacggcu gcgacuacgu cuccaacaag ggcgucgaca ccgucuccgu cggcaacacc     1320

cucuacuacg ucaacaagca ggagggccag ucccucuacg ucaagggcga gcccaucauc     1380

aacuucuacg acccccucgu cuuccccucc gacgaguucg acgccuccau cucccagguc     1440

aacgagaaga ucaaccaguc ccucgccuuc auccgcaagu ccgacgagcu ccuccacaac     1500

gucaacgccg gcaaguccac caccaacauc augaucacca ccaucaucau cgucaucauc     1560

gucauccucc ucucccucau cgccgucggc cuccuccucu acugcaaggc ccgcugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8169
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8169
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccuuaag gccaacgcua uuaccacaau acugacugca      120

gugacguucu gcuuugccag cggccagaau aucaccgaag aguucuacca auccacaugu      180

ucugcggucu caaaagggua uuugggagcu uuaagaacug guugguacac caguguuauu      240

acaaucgaac ugagcaacau uaaggagauc aaaugcaaug gcaccgacgc caaggugaaa      300

cuaauaaagc aggaacucga uaaguauaaa aacgcaguaa cugaccugca gcuucugaug      360

caguccacac ccgccaccgg gucuggaucg gcuaucgcau caggcguggc cgucuguaag      420

guguugcacc ucgaggguga gguuaauaaa auuaagagcg cucugcugag uacgaacaaa      480

gccguggucu cccucucugg gugcggagug agcguauuaa cuuuuaaggu ucuggaucuu      540

aagaauuaca ucgacaaaca auugcugccu auucuaaaca agcaguccug uucaauccca      600

aauauagaaa ccgugauuga guuccagcag aaaaacaaua ggcuccugga aaucacacgg      660

gaguuuagug ucaacgcggg cgugacuacc ccggugagca cauauaugcu uaccaauucu      720

gagcuguugu cccucauuaa cgauaugccc aucacgaaug accaaaagaa acugauguca      780

aacaacgucc agaucguucg ccagcagagc uacaguauua ugugcauaau caaggaagag      840

guguuagcau auguagugca acugccucuc uacggcguca uugauacucc auguuggaaa      900

cuucauacau cuccccugug caccacuaau acaaaggaag gguccaacau cuguuugacc      960

cgaacggacc guggauggua cugcgauaau gccgguagcg ugucguucuu uccucaggcu     1020

gagaccugua agguucaguc uaacagagug uucugcgaca caaugaacuc ccuaacucug     1080

ccaucagaag ucaaucucug caauguggau auauuuaacc ccaaauauga cuguaagauu     1140

augaccagua aaacagaugu aagcuccucu guuaucacua gccugggcgc caucguguca     1200

ugcuacggga agaccaaaug uacagcaagu aauaagugca ggggaauuau caagaccuuc     1260

uccaacggcu gugacuaugu cagcaauaaa gguguggaca cugucucugu ggggaacacg     1320

cuuuacuaug uuaauaagca agagggacag ucacuguacg ugaaaggcga gccuauuaua     1380

aacuuuuaug auccauuggu auucccgagu gacgaauuug augcuagcau cucccagguc     1440

aaugagaaga uuaaccaguc ucucgccuuc auccggaaau cggacgaacu guuacacaac     1500

gugaaugcgg gcaagagcac aaccaacauc augauuacua ccauaaucau uguuaucauu     1560

gugauccugc uaucccucau agccgucggg cugcuuuugu acugcaaggc acgcugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8170
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8170
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu gauccugaag gccaacgcca ucaccaccau ccugaccgcc      120

gugaccuucu gcuucgccag cggccagaac aucaccgagg aguucuacca gagcaccugc      180

agcgccguga gcaagggcua ccugggcgcc cugagaaccg gcugguacac cagcgugauc      240

accaucgagc ugagcaacau caaggagauc aagugcaacg gcaccgacgc caaggugaag      300

cugaucaagc aggagcugga caaguacaag aacgccguga ccgaccugca gcugcugaug      360

cagagcaccc ccgccaccgg cagcggcagc gccaucgcca gcggcguggc cgugugcaag      420

gugcugcacc uggagggcga ggugaacaag aucaagagcg cccugcugag caccaacaag      480

gccgugguga gccugagcgg cugcggcgug agcgugcuga ccuucaaggu gcuggaccug      540

aagaacuaca ucgacaagca gcugcugccc auccugaaca agcagagcug cagcaucccc      600

aacaucgaga ccgugaucga guuccagcag aagaacaaca gacugcugga gaucaccaga      660

gaguucagcg ugaacgccgg cgugaccacc cccgugagca ccuacaugcu gaccaacagc      720

gagcugcuga gccugaucaa cgacaugccc aucaccaacg accagaagaa gcugaugagc      780

aacaacgugc agaucgugag acagcagagc uacagcauca ugugcaucau caaggaggag      840

gugcuggccu acguggugca gcugccccug uacggcguga ucgacacccc cugcuggaag      900

cugcacacca gcccccugug caccaccaac accaaggagg gcagcaacau cugccugacc      960

agaaccgaca gaggcuggua cugcgacaac gccggcagcg ugagcuucuu cccccaggcc     1020

gagaccugca aggugcagag caacagagug uucugcgaca ccaugaacag ccugacccug     1080

cccagcgagg ugaaccugug caacguggac aucuucaacc ccaaguacga cugcaagauc     1140

augaccagca agaccgacgu gagcagcagc gugaucacca gccugggcgc caucgugagc     1200

ugcuacggca agaccaagug caccgccagc aacaagugca gaggcaucau caagaccuuc     1260

agcaacggcu gcgacuacgu gagcaacaag ggcguggaca ccgugagcgu gggcaacacc     1320

cuguacuacg ugaacaagca ggagggccag agccuguacg ugaagggcga gcccaucauc     1380

aacuucuacg acccccuggu guuccccagc gacgaguucg acgccagcau cagccaggug     1440

aacgagaaga ucaaccagag ccuggccuuc aucagaaaga gcgacgagcu gcugcacaac     1500

gugaacgccg gcaagagcac caccaacauc augaucacca ccaucaucau cgugaucauc     1560

gugauccugc ugagccugau cgccgugggc cugcugcugu acugcaaggc cagaugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8171
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8171
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagcugcu cauccugaag gccaacgcua uuaccacaau ccuuacggcc      120

gugaccuucu gcuuugcgag cggccagaau auuacagaag aguucuacca auccaccugu      180

ucugcuguca gcaaagggua ucugggagcc cucagaacag gcugguacac cuccguuauc      240

acaauugaac ugucuaacau caaggagauc aaaugcaaug ggaccgacgc caaggugaaa      300

cuuauuaagc aggaacugga uaaguauaaa aacgcuguga cggaccucca gcugcugaug      360

cagagcaccc ccgccacagg auccggcucu gcuaucgcca gcggggucgc gguguguaag      420

guucuccacc uggagggaga ggugaauaaa auuaaguccg cccuucugag caccaacaaa      480

gcugucgugu cucucuccgg cugcggcguu agcgugcuga cauuuaaggu ccuugaucug      540

aagaauuaca ucgacaaaca acuccugccu auucugaaca agcagucuug uuccaucccg      600

aauauugaaa ccgugaucga guuccagcag aaaaacaauc ggcuccugga aaucacgcgc      660

gaguuuagcg ugaacgccgg ggucacaacc cccguuucua cauauaugcu uaccaauucc      720

gagcugcuca gccugauuaa cgauaugccu aucaccaaug accaaaagaa acuuaugucc      780

aacaacgugc agauugugag acagcagucu uacagcauca ugugcauuau caaggaagag      840

guccuggcuu augugguuca acucccccug uacggaguga ucgauacacc uuguuggaaa      900

cugcauacga gcccccucug caccacaaau accaaggaag gcagcaacau uugucugaca      960

cggaccgacc gcggguggua cugcgauaau gccggaucug ucuccuucuu uccucaggcg     1020

gagacgugua aggugcagag caacagaguu uucugcgaca caaugaacuc ucuuacccug     1080

ccgagcgaag ugaaucucug caaugucgau aucuuuaacc ccaaauauga cuguaagauu     1140

augaccucca aaacagaugu gucuagcucc gucaucacca gccugggcgc cauugugucu     1200

ugcuacggga agacaaaaug uacggcuucc aauaagugcc ggggaaucau caagaccuuc     1260

agcaacggcu gugacuaugu uucuaauaaa ggcguggaca cagucuccgu ggggaacacc     1320

cuuuacuaug uuaauaagca agagggacag agccuguacg ugaaaggcga gccuauuauc     1380

aacuuuuaug auccccucgu cuucccuucc gacgaauuug augccucuau uagccaggug     1440

aaugagaaga ucaaccaguc ccuggcuuuc auucgcaaau cugacgaacu gcuccacaac     1500

gugaaugccg ggaaguccac aaccaacauc augauuacga ccaucaucau uguuaucauu     1560

gucauccugc uuucccugau ugccguggga cuccugcugu acugcaaggc uagaugagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8172
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8172
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuacu cauauugaaa gccaacgcaa ucacaacaau acuaaccgcc      120

guaacauuuu gcuucgcguc aggccaaaau auaacagaag aauuuuacca aucaacaugc      180

uccgccguau caaaaggaua ccuaggugca uuacgaaccg guugguacac aucaguaauc      240

acaauagaac uuuccaacau uaaagaaaua aaaugcaaug gcacagacgc aaaagucaaa      300

cuaauaaaac aagaacuaga caaauauaaa aacgccguca cagacuuaca acuauuaaug      360

caaagcacac cagcaacagg auccggauca gcaauagcau caggaguagc cgucuguaaa      420

guacuacacc uagaaggcga aguuaauaaa auuaaaucag cuuuauuauc aaccaacaaa      480

gcaguaguau cacuauccgg augcggaguc uccguccuaa cauucaaagu acuagaccuc      540

aagaauuaca uagauaaaca acuacuacca auacucaaca aacaaucaug uucaauacca      600

aacaucgaaa ccgucauaga auuucaacaa aaaaauaaua gacucuuaga aauaacacga      660

gaauuuagcg uaaacgcagg agucacaacc ccugucucaa cauacaugcu aaccaauucc      720

gaauuauuau cacucauaaa ugacaugcca auaacuaaug accaaaaaaa acuuauguca      780

aacaacguac aaauaguaag acaacaauca uauucaauaa ugugcauaau caaagaagaa      840

guuuuagcau auguaguaca acuaccacua uauggcguca uagacacacc augcuggaaa      900

uuacacacau caccucuaug cacaacaaac acaaaagaag gaagcaacau uugccuaacc      960

agaaccgaua gaggauggua cugcgauaac gcaggcucag uaucauucuu cccucaagcc     1020

gaaacuugca aaguccaauc aaauagaguc uucugcgaua caaugaacuc cuuaacuuua     1080

ccaucagaag uaaaucuaug caacguagau aucuuuaauc caaaauacga uugcaaaauc     1140

augacaucaa aaacagaugu aucaucuagu guaauuaccu cccuaggagc aauaguaagc     1200

ugcuacggaa aaacaaaaug caccgccucu aacaaauguc guggaauaau aaaaacauuc     1260

ucaaacggau gcgauuaugu aucaaauaaa ggugucgaca ccguaucagu aggcaauaca     1320

cuauacuaug uaaauaaaca agaaggacaa ucacucuacg ucaaagguga accaauaaua     1380

aacuucuacg acccacuugu auucccaagc gacgaauuug acgcaucaau aagccaagua     1440

aacgaaaaaa uaaaccaauc acuagcauuc aucagaaaau cagacgaacu acuccacaau     1500

guaaaugcag gaaaaucaac aaccaauauc augauaacaa ccauaauaau agucauaaua     1560

guaauacuau uaucccucau agccguugga cuacuccuau auuguaaagc acgauaagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8173
<211>  1892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8173
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaacuccu cauccucaaa gccaacgcca ucaccaccau acucaccgca      120

guaaccuucu gcuucgcauc cggccaaaac aucacagaag aguucuacca gaguaccugc      180

uccgccgucu ccaaaggcua ccuuggcgcc cuccguaccg ggugguacac auccgucauc      240

acaaucgaac ucuccaacau caaagaaaua aagugcaacg gcacagacgc caaaguaaaa      300

cugauaaagc aagaacucga caaauacaaa aacgccguaa ccgaccucca gcuacuaaug      360

caauccacuc ccgccaccgg cagcggaucc gccaucgccu ccggaguagc cgucuguaaa      420

gucuuacacc ucgaaggcga agugaacaaa aucaaauccg cccuacucuc aaccaacaaa      480

gccguaguau cacucuccgg gugcggcguu ucagugcuaa cguucaaagu ccuugaccuc      540

aaaaacuaca ucgacaaaca acuccucccc auccuaaaua aacaauccug cuccauaccc      600

aacaucgaga cugucaucga guuccagcag aaaaacaacc gacuccucga aaucacacgc      660

gaguucucug ucaacgccgg cgucacaacc cccgucucca cauacaugcu caccaacagc      720

gaacuccucu cccuaaucaa ugacaugccc aucaccaacg accaaaagaa acucauguca      780

aacaacgucc aaaucguccg ccaacaaucc uacagcauca ugugcaucau caaagaagaa      840

guucucgcau acguaguaca acucccccuc uacggaguga ucgacacccc cugcuggaaa      900

cuacacacca gcccgcuuug caccacaaac accaaggaag gcuccaacau cugccucacu      960

cgaaccgacc gcggcuggua cugcgacaac gcaggcuccg ucaguuucuu uccccaagca     1020

gaaacaugca aaguccaauc caaccgagua uucugcgaca ccaugaacuc ccucacccua     1080

ccauccgaag uuaaccuaug caacguggac aucuucaacc ccaaguacga cugcaaaauu     1140

augaccucca aaaccgacgu auccuccagc gucaucacca gccucggagc aauagucucc     1200

ugcuacggca agaccaagug caccgcuucc aacaaguguc gcggaaucau caaaaccuuc     1260

ucaaacggcu gcgacuacgu cuccaacaaa ggcgucgaca ccguauccgu aggaaacacc     1320

cuauacuacg ucaacaaaca agaaggacaa ucccucuaug ucaaaggcga acccaucauc     1380

aauuucuacg acccccuagu cuucccuucc gacgaguucg acgcguccau cagccaaguc     1440

aaugaaaaga ucaaccagag ccuggcauuc auccgcaaau ccgacgaacu ccuccacaac     1500

gucaacgcgg gaaaauccac gacaaacauc augaucacca ccaucaucau cgucaucaua     1560

gucauucucc uuucucucau cgccguggga cuacuucucu acugcaaagc ccgauaagga     1620

cuaguggaag cauuuuccug gcugauuaaa agaaauuacu cagcuauggu caucuguucc     1680

uguuagaagg cuaugcagca uauuauauac uaugcgcaug uuaugaaaug cauaauaaaa     1740

aauuuuaaaa aaucuaaaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1860

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1892


<210>  8174
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8174
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8175
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8175
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8176
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8176
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8177
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8177
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cugaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8178
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8178
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8179
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8179
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag augaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8180
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8180
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auugaaagcc      120

aacgcaauca caacaauacu aaccgccgua acauuuugcu ucgcgucagg ccaaaauaua      180

acagaagaau uuuaccaauc aacaugcucc gccguaucaa aaggauaccu aggugcauua      240

cgaaccgguu gguacacauc aguaaucaca auagaacuuu ccaacauuaa agaaauaaaa      300

ugcaauggca cagacgcaaa agucaaacua auaaaacaag aacuagacaa auauaaaaac      360

gccgucacag acuuacaacu auuaaugcaa agcacaccag caacaggauc cggaucagca      420

auagcaucag gaguagccgu cuguaaagua cuacaccuag aaggcgaagu uaauaaaauu      480

aaaucagcuu uauuaucaac caacaaagca guaguaucac uauccggaug cggagucucc      540

guccuaacau ucaaaguacu agaccucaag aauuacauag auaaacaacu acuaccaaua      600

cucaacaaac aaucauguuc aauaccaaac aucgaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac ucuuagaaau aacacgagaa uuuagcguaa acgcaggagu cacaaccccu      720

gucucaacau acaugcuaac caauuccgaa uuauuaucac ucauaaauga caugccaaua      780

acuaaugacc aaaaaaaacu uaugucaaac aacguacaaa uaguaagaca acaaucauau      840

ucaauaaugu gcauaaucaa agaagaaguu uuagcauaug uaguacaacu accacuauau      900

ggcgucauag acacaccaug cuggaaauua cacacaucac cucuaugcac aacaaacaca      960

aaagaaggaa gcaacauuug ccuaaccaga accgauagag gaugguacug cgauaacgca     1020

ggcucaguau cauucuuccc ucaagccgaa acuugcaaag uccaaucaaa uagagucuuc     1080

ugcgauacaa ugaacuccuu aacuuuacca ucagaaguaa aucuaugcaa cguagauauc     1140

uuuaauccaa aauacgauug caaaaucaug acaucaaaaa cagauguauc aucuagugua     1200

auuaccuccc uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucuaac     1260

aaaugucgug gaauaauaaa aacauucuca aacggaugcg auuauguauc aaauaaaggu     1320

gucgacaccg uaucaguagg caauacacua uacuauguaa auaaacaaga aggacaauca     1380

cucuacguca aaggugaacc aauaauaaac uucuacgacc cacuuguauu cccaagcgac     1440

gaauuugacg caucaauaag ccaaguaaac gaaaaaauaa accaaucacu agcauucauc     1500

agaaaaucag acgaacuacu ccacaaugua aaugcaggaa aaucaacaac caauaucaug     1560

auaacaacca uaauaauagu cauaauagua auacuauuau cccucauagc cguuggacua     1620

cuccuauauu guaaagcacg auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8181
<211>  1907
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8181
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauca ccaccauacu caccgcagua accuucugcu ucgcauccgg ccaaaacauc      180

acagaagagu ucuaccagag uaccugcucc gccgucucca aaggcuaccu uggcgcccuc      240

cguaccgggu gguacacauc cgucaucaca aucgaacucu ccaacaucaa agaaauaaag      300

ugcaacggca cagacgccaa aguaaaacug auaaagcaag aacucgacaa auacaaaaac      360

gccguaaccg accuccagcu acuaaugcaa uccacucccg ccaccggcag cggauccgcc      420

aucgccuccg gaguagccgu cuguaaaguc uuacaccucg aaggcgaagu gaacaaaauc      480

aaauccgccc uacucucaac caacaaagcc guaguaucac ucuccgggug cggcguuuca      540

gugcuaacgu ucaaaguccu ugaccucaaa aacuacaucg acaaacaacu ccuccccauc      600

cuaaauaaac aauccugcuc cauacccaac aucgagacug ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau cacacgcgag uucucuguca acgccggcgu cacaaccccc      720

gucuccacau acaugcucac caacagcgaa cuccucuccc uaaucaauga caugcccauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgcca acaauccuac      840

agcaucaugu gcaucaucaa agaagaaguu cucgcauacg uaguacaacu cccccucuac      900

ggagugaucg acacccccug cuggaaacua cacaccagcc cgcuuugcac cacaaacacc      960

aaggaaggcu ccaacaucug ccucacucga accgaccgcg gcugguacug cgacaacgca     1020

ggcuccguca guuucuuucc ccaagcagaa acaugcaaag uccaauccaa ccgaguauuc     1080

ugcgacacca ugaacucccu cacccuacca uccgaaguua accuaugcaa cguggacauc     1140

uucaacccca aguacgacug caaaauuaug accuccaaaa ccgacguauc cuccagcguc     1200

aucaccagcc ucggagcaau agucuccugc uacggcaaga ccaagugcac cgcuuccaac     1260

aagugucgcg gaaucaucaa aaccuucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacaccg uauccguagg aaacacccua uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc caucaucaau uucuacgacc cccuagucuu cccuuccgac     1440

gaguucgacg cguccaucag ccaagucaau gaaaagauca accagagccu ggcauucauc     1500

cgcaaauccg acgaacuccu ccacaacguc aacgcgggaa aauccacgac aaacaucaug     1560

aucaccacca ucaucaucgu caucauaguc auucuccuuu cucucaucgc cgugggacua     1620

cuucucuacu gcaaagcccg auaaggacua guaauaagga aacuguauga augucugugg     1680

gcaggaagug aagagauccu ucuguaaagg uuuuuggaau uaugucugcu gaauaauaaa     1740

cuuuuuugaa auaauaaauc ugguagaaaa augagaucua aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1860

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1907


<210>  8182
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8182
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cggaccggcu gguacaccuc cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggga ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag uccaccccgg caaccggcuc cggcuccgcc      420

aucgcgagcg gcgucgccgu gugcaaggug cugcaccucg agggggaggu caacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggugagcc ucuccggcug cggcgucagc      540

gugcugaccu ucaaggugcu ggaccucaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcuc cauccccaac aucgagacgg ugaucgaguu ccagcagaag      660

aacaaccggc uccuggagau cacccgcgag uucagcguga acgccggggu caccaccccc      720

guguccacgu acaugcugac caacagcgag cuccuguccc ugaucaacga caugccgauc      780

accaacgacc agaagaagcu caugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggcguacg ugguccagcu gccccucuac      900

ggcgugaucg acacccccug cuggaagcug cacacgagcc cccugugcac caccaacacc      960

aaggaggggu ccaacaucug ccucacgcgc accgaccggg gcugguacug cgacaacgcc     1020

ggcagcgucu ccuucuuccc gcaggccgag accugcaagg ugcagagcaa ccgcguguuc     1080

ugcgacacca ugaacucccu gacgcugccc agcgagguaa accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgugag cuccagcgug     1200

aucaccuccc ugggggccau cgucagcugc uacggcaaga cgaagugcac cgccagcaac     1260

aagugccggg ggaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg uguccgucgg gaacacccug uacuacguga acaagcagga gggccagagc     1380

cucuacguga agggggagcc caucaucaac uucuacgacc cgcuggucuu ccccuccgac     1440

gaguucgacg cgagcaucuc ccaggugaac gagaagauca accagagccu ggccuucauc     1500

cgcaaguccg acgagcugcu ccacaacgug aacgccggca agagcacgac caacaucaug     1560

aucaccacca ucaucaucgu caucaucgug auccugcugu cccucaucgc cguggggcug     1620

cugcucuacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8183
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8183
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgccauca ccaccauccu gacggcggug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccaguc cacgugcagc gccgucucca agggguaccu cggcgcccug      240

cgcaccgggu gguacaccag cgugaucacc aucgagcugu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcuc aucaagcagg agcuggacaa guacaagaac      360

gcggucacgg accugcagcu ccugaugcag agcacccccg ccaccggguc cggcagcgcc      420

aucgccuccg gcguggcggu gugcaagguc cugcaccucg agggggaggu gaacaagauc      480

aagagcgccc ugcuguccac caacaaggcc guggucagcc ucuccggcug cggggugagc      540

gugcugacgu ucaagguccu ggaccucaag aacuacaucg acaagcagcu gcugccgauc      600

cucaacaagc aguccugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaaccggc ugcuggagau cacccgcgag uucuccguga acgccggcgu caccacgccc      720

gugagcaccu acaugcucac caacuccgag cugcugagcc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucguccggca gcaguccuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg ugguccagcu cccgcuguac      900

ggggugaucg acacgcccug cuggaagcug cacaccagcc cccucugcac caccaacacg      960

aaggagggcu ccaacaucug ccugacccgc accgaccggg gcugguacug cgacaacgcg     1020

ggguccguga gcuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcguguuc     1080

ugcgacacga ugaacagccu gacccucccg uccgagguca accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacguguc cagcuccguc     1200

aucacgagcc ugggcgccau cguguccugc uacgggaaga ccaagugcac cgccagcaac     1260

aagugccggg gcaucaucaa gaccuucucc aacggcugcg acuacgugag caacaagggg     1320

gucgacacgg uguccguggg caacacccuc uacuacguca acaagcagga ggggcagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu cccgagcgac     1440

gaguucgacg ccuccaucag ccaggucaac gagaagauca accagucccu cgcguucauc     1500

cgcaagagcg acgagcugcu gcacaacgug aacgccggga aguccaccac caacaucaug     1560

aucaccacga ucaucaucgu gaucaucguc auccuccuga gccugaucgc cgugggccuc     1620

cugcuguacu gcaaggcccg gugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8184
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8184
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcuccucau ccucaaggcc      120

aacgccauca ccaccauccu caccgccguc accuucugcu ucgccuccgg ccagaacauc      180

accgaggagu ucuaccaguc caccugcucc gccgucucca agggcuaccu cggcgcccuc      240

cgcaccggcu gguacaccuc cgucaucacc aucgagcucu ccaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggucaagcuc aucaagcagg agcucgacaa guacaagaac      360

gccgucaccg accuccagcu ccucaugcag uccacccccg ccaccggcuc cggcuccgcc      420

aucgccuccg gcgucgccgu cugcaagguc cuccaccucg agggcgaggu caacaagauc      480

aaguccgccc uccucuccac caacaaggcc gucgucuccc ucuccggcug cggcgucucc      540

guccucaccu ucaagguccu cgaccucaag aacuacaucg acaagcagcu ccuccccauc      600

cucaacaagc aguccugcuc cauccccaac aucgagaccg ucaucgaguu ccagcagaag      660

aacaaccgcc uccucgagau cacccgcgag uucuccguca acgccggcgu caccaccccc      720

gucuccaccu acaugcucac caacuccgag cuccucuccc ucaucaacga caugcccauc      780

accaacgacc agaagaagcu cauguccaac aacguccaga ucguccgcca gcaguccuac      840

uccaucaugu gcaucaucaa ggaggagguc cucgccuacg ucguccagcu cccccucuac      900

ggcgucaucg acacccccug cuggaagcuc cacaccuccc cccucugcac caccaacacc      960

aaggagggcu ccaacaucug ccucacccgc accgaccgcg gcugguacug cgacaacgcc     1020

ggcuccgucu ccuucuuccc ccaggccgag accugcaagg uccaguccaa ccgcgucuuc     1080

ugcgacacca ugaacucccu cacccucccc uccgagguca accucugcaa cgucgacauc     1140

uucaacccca aguacgacug caagaucaug accuccaaga ccgacgucuc cuccuccguc     1200

aucaccuccc ucggcgccau cgucuccugc uacggcaaga ccaagugcac cgccuccaac     1260

aagugccgcg gcaucaucaa gaccuucucc aacggcugcg acuacgucuc caacaagggc     1320

gucgacaccg ucuccgucgg caacacccuc uacuacguca acaagcagga gggccagucc     1380

cucuacguca agggcgagcc caucaucaac uucuacgacc cccucgucuu ccccuccgac     1440

gaguucgacg ccuccaucuc ccaggucaac gagaagauca accagucccu cgccuucauc     1500

cgcaaguccg acgagcuccu ccacaacguc aacgccggca aguccaccac caacaucaug     1560

aucaccacca ucaucaucgu caucaucguc auccuccucu cccucaucgc cgucggccuc     1620

cuccucuacu gcaaggcccg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8185
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8185
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccuuaaggcc      120

aacgcuauua ccacaauacu gacugcagug acguucugcu uugccagcgg ccagaauauc      180

accgaagagu ucuaccaauc cacauguucu gcggucucaa aaggguauuu gggagcuuua      240

agaacugguu gguacaccag uguuauuaca aucgaacuga gcaacauuaa ggagaucaaa      300

ugcaauggca ccgacgccaa ggugaaacua auaaagcagg aacucgauaa guauaaaaac      360

gcaguaacug accugcagcu ucugaugcag uccacacccg ccaccggguc uggaucggcu      420

aucgcaucag gcguggccgu cuguaaggug uugcaccucg agggugaggu uaauaaaauu      480

aagagcgcuc ugcugaguac gaacaaagcc guggucuccc ucucugggug cggagugagc      540

guauuaacuu uuaagguucu ggaucuuaag aauuacaucg acaaacaauu gcugccuauu      600

cuaaacaagc aguccuguuc aaucccaaau auagaaaccg ugauugaguu ccagcagaaa      660

aacaauaggc uccuggaaau cacacgggag uuuaguguca acgcgggcgu gacuaccccg      720

gugagcacau auaugcuuac caauucugag cuguuguccc ucauuaacga uaugcccauc      780

acgaaugacc aaaagaaacu gaugucaaac aacguccaga ucguucgcca gcagagcuac      840

aguauuaugu gcauaaucaa ggaagaggug uuagcauaug uagugcaacu gccucucuac      900

ggcgucauug auacuccaug uuggaaacuu cauacaucuc cccugugcac cacuaauaca      960

aaggaagggu ccaacaucug uuugacccga acggaccgug gaugguacug cgauaaugcc     1020

gguagcgugu cguucuuucc ucaggcugag accuguaagg uucagucuaa cagaguguuc     1080

ugcgacacaa ugaacucccu aacucugcca ucagaaguca aucucugcaa uguggauaua     1140

uuuaacccca aauaugacug uaagauuaug accaguaaaa cagauguaag cuccucuguu     1200

aucacuagcc ugggcgccau cgugucaugc uacgggaaga ccaaauguac agcaaguaau     1260

aagugcaggg gaauuaucaa gaccuucucc aacggcugug acuaugucag caauaaaggu     1320

guggacacug ucucuguggg gaacacgcuu uacuauguua auaagcaaga gggacaguca     1380

cuguacguga aaggcgagcc uauuauaaac uuuuaugauc cauugguauu cccgagugac     1440

gaauuugaug cuagcaucuc ccaggucaau gagaagauua accagucucu cgccuucauc     1500

cggaaaucgg acgaacuguu acacaacgug aaugcgggca agagcacaac caacaucaug     1560

auuacuacca uaaucauugu uaucauugug auccugcuau cccucauagc cgucgggcug     1620

cuuuuguacu gcaaggcacg cugaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8186
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8186
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcugau ccugaaggcc      120

aacgccauca ccaccauccu gaccgccgug accuucugcu ucgccagcgg ccagaacauc      180

accgaggagu ucuaccagag caccugcagc gccgugagca agggcuaccu gggcgcccug      240

agaaccggcu gguacaccag cgugaucacc aucgagcuga gcaacaucaa ggagaucaag      300

ugcaacggca ccgacgccaa ggugaagcug aucaagcagg agcuggacaa guacaagaac      360

gccgugaccg accugcagcu gcugaugcag agcacccccg ccaccggcag cggcagcgcc      420

aucgccagcg gcguggccgu gugcaaggug cugcaccugg agggcgaggu gaacaagauc      480

aagagcgccc ugcugagcac caacaaggcc guggugagcc ugagcggcug cggcgugagc      540

gugcugaccu ucaaggugcu ggaccugaag aacuacaucg acaagcagcu gcugcccauc      600

cugaacaagc agagcugcag cauccccaac aucgagaccg ugaucgaguu ccagcagaag      660

aacaacagac ugcuggagau caccagagag uucagcguga acgccggcgu gaccaccccc      720

gugagcaccu acaugcugac caacagcgag cugcugagcc ugaucaacga caugcccauc      780

accaacgacc agaagaagcu gaugagcaac aacgugcaga ucgugagaca gcagagcuac      840

agcaucaugu gcaucaucaa ggaggaggug cuggccuacg uggugcagcu gccccuguac      900

ggcgugaucg acacccccug cuggaagcug cacaccagcc cccugugcac caccaacacc      960

aaggagggca gcaacaucug ccugaccaga accgacagag gcugguacug cgacaacgcc     1020

ggcagcguga gcuucuuccc ccaggccgag accugcaagg ugcagagcaa cagaguguuc     1080

ugcgacacca ugaacagccu gacccugccc agcgagguga accugugcaa cguggacauc     1140

uucaacccca aguacgacug caagaucaug accagcaaga ccgacgugag cagcagcgug     1200

aucaccagcc ugggcgccau cgugagcugc uacggcaaga ccaagugcac cgccagcaac     1260

aagugcagag gcaucaucaa gaccuucagc aacggcugcg acuacgugag caacaagggc     1320

guggacaccg ugagcguggg caacacccug uacuacguga acaagcagga gggccagagc     1380

cuguacguga agggcgagcc caucaucaac uucuacgacc cccugguguu ccccagcgac     1440

gaguucgacg ccagcaucag ccaggugaac gagaagauca accagagccu ggccuucauc     1500

agaaagagcg acgagcugcu gcacaacgug aacgccggca agagcaccac caacaucaug     1560

aucaccacca ucaucaucgu gaucaucgug auccugcuga gccugaucgc cgugggccug     1620

cugcuguacu gcaaggccag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8187
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8187
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agcugcucau ccugaaggcc      120

aacgcuauua ccacaauccu uacggccgug accuucugcu uugcgagcgg ccagaauauu      180

acagaagagu ucuaccaauc caccuguucu gcugucagca aaggguaucu gggagcccuc      240

agaacaggcu gguacaccuc cguuaucaca auugaacugu cuaacaucaa ggagaucaaa      300

ugcaauggga ccgacgccaa ggugaaacuu auuaagcagg aacuggauaa guauaaaaac      360

gcugugacgg accuccagcu gcugaugcag agcacccccg ccacaggauc cggcucugcu      420

aucgccagcg gggucgcggu guguaagguu cuccaccugg agggagaggu gaauaaaauu      480

aaguccgccc uucugagcac caacaaagcu gucgugucuc ucuccggcug cggcguuagc      540

gugcugacau uuaagguccu ugaucugaag aauuacaucg acaaacaacu ccugccuauu      600

cugaacaagc agucuuguuc caucccgaau auugaaaccg ugaucgaguu ccagcagaaa      660

aacaaucggc uccuggaaau cacgcgcgag uuuagcguga acgccggggu cacaaccccc      720

guuucuacau auaugcuuac caauuccgag cugcucagcc ugauuaacga uaugccuauc      780

accaaugacc aaaagaaacu uauguccaac aacgugcaga uugugagaca gcagucuuac      840

agcaucaugu gcauuaucaa ggaagagguc cuggcuuaug ugguucaacu cccccuguac      900

ggagugaucg auacaccuug uuggaaacug cauacgagcc cccucugcac cacaaauacc      960

aaggaaggca gcaacauuug ucugacacgg accgaccgcg ggugguacug cgauaaugcc     1020

ggaucugucu ccuucuuucc ucaggcggag acguguaagg ugcagagcaa cagaguuuuc     1080

ugcgacacaa ugaacucucu uacccugccg agcgaaguga aucucugcaa ugucgauauc     1140

uuuaacccca aauaugacug uaagauuaug accuccaaaa cagauguguc uagcuccguc     1200

aucaccagcc ugggcgccau ugugucuugc uacgggaaga caaaauguac ggcuuccaau     1260

aagugccggg gaaucaucaa gaccuucagc aacggcugug acuauguuuc uaauaaaggc     1320

guggacacag ucuccguggg gaacacccuu uacuauguua auaagcaaga gggacagagc     1380

cuguacguga aaggcgagcc uauuaucaac uuuuaugauc cccucgucuu cccuuccgac     1440

gaauuugaug ccucuauuag ccaggugaau gagaagauca accagucccu ggcuuucauu     1500

cgcaaaucug acgaacugcu ccacaacgug aaugccggga aguccacaac caacaucaug     1560

auuacgacca ucaucauugu uaucauuguc auccugcuuu cccugauugc cgugggacuc     1620

cugcuguacu gcaaggcuag augaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8188
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8188
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuacucau auugaaagcc      120

aacgcaauca caacaauacu aaccgccgua acauuuugcu ucgcgucagg ccaaaauaua      180

acagaagaau uuuaccaauc aacaugcucc gccguaucaa aaggauaccu aggugcauua      240

cgaaccgguu gguacacauc aguaaucaca auagaacuuu ccaacauuaa agaaauaaaa      300

ugcaauggca cagacgcaaa agucaaacua auaaaacaag aacuagacaa auauaaaaac      360

gccgucacag acuuacaacu auuaaugcaa agcacaccag caacaggauc cggaucagca      420

auagcaucag gaguagccgu cuguaaagua cuacaccuag aaggcgaagu uaauaaaauu      480

aaaucagcuu uauuaucaac caacaaagca guaguaucac uauccggaug cggagucucc      540

guccuaacau ucaaaguacu agaccucaag aauuacauag auaaacaacu acuaccaaua      600

cucaacaaac aaucauguuc aauaccaaac aucgaaaccg ucauagaauu ucaacaaaaa      660

aauaauagac ucuuagaaau aacacgagaa uuuagcguaa acgcaggagu cacaaccccu      720

gucucaacau acaugcuaac caauuccgaa uuauuaucac ucauaaauga caugccaaua      780

acuaaugacc aaaaaaaacu uaugucaaac aacguacaaa uaguaagaca acaaucauau      840

ucaauaaugu gcauaaucaa agaagaaguu uuagcauaug uaguacaacu accacuauau      900

ggcgucauag acacaccaug cuggaaauua cacacaucac cucuaugcac aacaaacaca      960

aaagaaggaa gcaacauuug ccuaaccaga accgauagag gaugguacug cgauaacgca     1020

ggcucaguau cauucuuccc ucaagccgaa acuugcaaag uccaaucaaa uagagucuuc     1080

ugcgauacaa ugaacuccuu aacuuuacca ucagaaguaa aucuaugcaa cguagauauc     1140

uuuaauccaa aauacgauug caaaaucaug acaucaaaaa cagauguauc aucuagugua     1200

auuaccuccc uaggagcaau aguaagcugc uacggaaaaa caaaaugcac cgccucuaac     1260

aaaugucgug gaauaauaaa aacauucuca aacggaugcg auuauguauc aaauaaaggu     1320

gucgacaccg uaucaguagg caauacacua uacuauguaa auaaacaaga aggacaauca     1380

cucuacguca aaggugaacc aauaauaaac uucuacgacc cacuuguauu cccaagcgac     1440

gaauuugacg caucaauaag ccaaguaaac gaaaaaauaa accaaucacu agcauucauc     1500

agaaaaucag acgaacuacu ccacaaugua aaugcaggaa aaucaacaac caauaucaug     1560

auaacaacca uaauaauagu cauaauagua auacuauuau cccucauagc cguuggacua     1620

cuccuauauu guaaagcacg auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8189
<211>  2139
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8189
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aacuccucau ccucaaagcc      120

aacgccauca ccaccauacu caccgcagua accuucugcu ucgcauccgg ccaaaacauc      180

acagaagagu ucuaccagag uaccugcucc gccgucucca aaggcuaccu uggcgcccuc      240

cguaccgggu gguacacauc cgucaucaca aucgaacucu ccaacaucaa agaaauaaag      300

ugcaacggca cagacgccaa aguaaaacug auaaagcaag aacucgacaa auacaaaaac      360

gccguaaccg accuccagcu acuaaugcaa uccacucccg ccaccggcag cggauccgcc      420

aucgccuccg gaguagccgu cuguaaaguc uuacaccucg aaggcgaagu gaacaaaauc      480

aaauccgccc uacucucaac caacaaagcc guaguaucac ucuccgggug cggcguuuca      540

gugcuaacgu ucaaaguccu ugaccucaaa aacuacaucg acaaacaacu ccuccccauc      600

cuaaauaaac aauccugcuc cauacccaac aucgagacug ucaucgaguu ccagcagaaa      660

aacaaccgac uccucgaaau cacacgcgag uucucuguca acgccggcgu cacaaccccc      720

gucuccacau acaugcucac caacagcgaa cuccucuccc uaaucaauga caugcccauc      780

accaacgacc aaaagaaacu caugucaaac aacguccaaa ucguccgcca acaauccuac      840

agcaucaugu gcaucaucaa agaagaaguu cucgcauacg uaguacaacu cccccucuac      900

ggagugaucg acacccccug cuggaaacua cacaccagcc cgcuuugcac cacaaacacc      960

aaggaaggcu ccaacaucug ccucacucga accgaccgcg gcugguacug cgacaacgca     1020

ggcuccguca guuucuuucc ccaagcagaa acaugcaaag uccaauccaa ccgaguauuc     1080

ugcgacacca ugaacucccu cacccuacca uccgaaguua accuaugcaa cguggacauc     1140

uucaacccca aguacgacug caaaauuaug accuccaaaa ccgacguauc cuccagcguc     1200

aucaccagcc ucggagcaau agucuccugc uacggcaaga ccaagugcac cgcuuccaac     1260

aagugucgcg gaaucaucaa aaccuucuca aacggcugcg acuacgucuc caacaaaggc     1320

gucgacaccg uauccguagg aaacacccua uacuacguca acaaacaaga aggacaaucc     1380

cucuauguca aaggcgaacc caucaucaau uucuacgacc cccuagucuu cccuuccgac     1440

gaguucgacg cguccaucag ccaagucaau gaaaagauca accagagccu ggcauucauc     1500

cgcaaauccg acgaacuccu ccacaacguc aacgcgggaa aauccacgac aaacaucaug     1560

aucaccacca ucaucaucgu caucauaguc auucuccuuu cucucaucgc cgugggacua     1620

cuucucuacu gcaaagcccg auaaggacua gugaagggaa cacccaaauu uaauucagcc     1680

uuaagcacaa uuaauuaaga gugaaacgua auuguacaag caguugguca cccaccauag     1740

ggcaugauca acaccgcaac cuuuccuuuu ucccccagug auucugaaaa accccucuuc     1800

ccuucagcuu gcuuagaugu uccaaauuua guaagcuuaa ggcggccuac agaagaaaaa     1860

gaaaaaaaag gccacaaaag uucccucuca cuuucaguaa auaaaauaaa agcagcaaca     1920

gaaauaaaga aauaaaugaa auucaaaaug aaauaaauau uguguugugc agcauuaaaa     1980

aaucaauaaa aauuaaaaau gagcaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2100

cccccccccc caaaggcucu uuucagagcc accagaauu                            2139


<210>  8190
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8190
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc      420

accccggcaa ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug      480

caccucgagg gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gugagccucu ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc      660

gagacgguga ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc      720

agcgugaacg ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc      780

cugucccuga ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gcguacgugg uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac      960

acgagccccc ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc     1020

gaccggggcu gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc     1080

ugcaaggugc agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc     1140

gagguaaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac     1260

ggcaagacga agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc     1440

uacgacccgc uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag     1500

aagaucaacc agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac     1560

gccggcaaga gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc     1620

cugcuguccc ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8191
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8191
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc      240

gucuccaagg gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc      300

gagcugucca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc      360

aagcaggagc uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc      420

acccccgcca ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug      480

caccucgagg gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug      540

gucagccucu ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac      600

uacaucgaca agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc      720

uccgugaacg ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug      780

cugagccuca ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac      960

accagccccc ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc     1020

gaccggggcu gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc     1140

gaggucaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac     1260

gggaagacca agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac     1380

uacgucaaca agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag     1500

aagaucaacc agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac     1560

gccgggaagu ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc     1620

cuccugagcc ugaucgccgu gggccuccug cuguacugca aggcccggug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8192
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8192
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc      180

uucugcuucg ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc      240

gucuccaagg gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc      300

gagcucucca acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc      360

aagcaggagc ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc      420

acccccgcca ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc      480

caccucgagg gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc      540

gucucccucu ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac      600

uacaucgaca agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc      660

gagaccguca ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc      720

uccgucaacg ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc      780

cucucccuca ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac      840

guccagaucg uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc      900

gccuacgucg uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac      960

accucccccc ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc     1020

gaccgcggcu gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc     1080

ugcaaggucc aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc     1140

gaggucaacc ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

uccaagaccg acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac     1260

ggcaagacca agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac     1320

ggcugcgacu acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac     1380

uacgucaaca agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc     1440

uacgaccccc ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag     1500

aagaucaacc agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac     1560

gccggcaagu ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc     1620

cuccucuccc ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8193
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8193
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg      180

uucugcuuug ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg      240

gucucaaaag gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc      300

gaacugagca acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua      360

aagcaggaac ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc      420

acacccgcca ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug      480

caccucgagg gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug      540

gucucccucu cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau      600

uacaucgaca aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua      660

gaaaccguga uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu      720

agugucaacg cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug      780

uugucccuca uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac      840

guccagaucg uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua      900

gcauauguag ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau      960

acaucucccc ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg     1020

gaccguggau gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc     1080

uguaagguuc agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca     1140

gaagucaauc ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc     1200

aguaaaacag auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac     1260

gggaagacca aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac     1320

ggcugugacu augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac     1380

uauguuaaua agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu     1440

uaugauccau ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag     1500

aagauuaacc agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau     1560

gcgggcaaga gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc     1620

cugcuauccc ucauagccgu cgggcugcuu uuguacugca aggcacgcug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8194
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8194
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc      180

uucugcuucg ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc      240

gugagcaagg gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc      300

gagcugagca acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc      360

aagcaggagc uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc      420

acccccgcca ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug      480

caccuggagg gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug      540

gugagccuga gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac      600

uacaucgaca agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc      660

gagaccguga ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc      720

agcgugaacg ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug      780

cugagccuga ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac      840

gugcagaucg ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug      900

gccuacgugg ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac      960

accagccccc ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc     1020

gacagaggcu gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc     1080

ugcaaggugc agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc     1140

gaggugaacc ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc     1200

agcaagaccg acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac     1260

ggcaagacca agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac     1320

ggcugcgacu acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac     1380

uacgugaaca agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc     1440

uacgaccccc ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag     1500

aagaucaacc agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac     1560

gccggcaaga gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc     1620

cugcugagcc ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8195
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8195
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggagc ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc      180

uucugcuuug cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu      240

gucagcaaag gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu      300

gaacugucua acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu      360

aagcaggaac uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc      420

acccccgcca caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc      480

caccuggagg gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc      540

gugucucucu ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau      600

uacaucgaca aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu      660

gaaaccguga ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu      720

agcgugaacg ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug      780

cucagccuga uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac      840

gugcagauug ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug      900

gcuuaugugg uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau      960

acgagccccc ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc     1020

gaccgcgggu gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg     1080

uguaaggugc agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc     1140

gaagugaauc ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc     1200

uccaaaacag augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac     1260

gggaagacaa aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac     1320

ggcugugacu auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac     1380

uauguuaaua agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu     1440

uaugaucccc ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag     1500

aagaucaacc agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau     1560

gccgggaagu ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc     1620

cugcuuuccc ugauugccgu gggacuccug cuguacugca aggcuagaug aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8196
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8196
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uacucauauu gaaagccaac gcaaucacaa caauacuaac cgccguaaca      180

uuuugcuucg cgucaggcca aaauauaaca gaagaauuuu accaaucaac augcuccgcc      240

guaucaaaag gauaccuagg ugcauuacga accgguuggu acacaucagu aaucacaaua      300

gaacuuucca acauuaaaga aauaaaaugc aauggcacag acgcaaaagu caaacuaaua      360

aaacaagaac uagacaaaua uaaaaacgcc gucacagacu uacaacuauu aaugcaaagc      420

acaccagcaa caggauccgg aucagcaaua gcaucaggag uagccgucug uaaaguacua      480

caccuagaag gcgaaguuaa uaaaauuaaa ucagcuuuau uaucaaccaa caaagcagua      540

guaucacuau ccggaugcgg agucuccguc cuaacauuca aaguacuaga ccucaagaau      600

uacauagaua aacaacuacu accaauacuc aacaaacaau cauguucaau accaaacauc      660

gaaaccguca uagaauuuca acaaaaaaau aauagacucu uagaaauaac acgagaauuu      720

agcguaaacg caggagucac aaccccuguc ucaacauaca ugcuaaccaa uuccgaauua      780

uuaucacuca uaaaugacau gccaauaacu aaugaccaaa aaaaacuuau gucaaacaac      840

guacaaauag uaagacaaca aucauauuca auaaugugca uaaucaaaga agaaguuuua      900

gcauauguag uacaacuacc acuauauggc gucauagaca caccaugcug gaaauuacac      960

acaucaccuc uaugcacaac aaacacaaaa gaaggaagca acauuugccu aaccagaacc     1020

gauagaggau gguacugcga uaacgcaggc ucaguaucau ucuucccuca agccgaaacu     1080

ugcaaagucc aaucaaauag agucuucugc gauacaauga acuccuuaac uuuaccauca     1140

gaaguaaauc uaugcaacgu agauaucuuu aauccaaaau acgauugcaa aaucaugaca     1200

ucaaaaacag auguaucauc uaguguaauu accucccuag gagcaauagu aagcugcuac     1260

ggaaaaacaa aaugcaccgc cucuaacaaa ugucguggaa uaauaaaaac auucucaaac     1320

ggaugcgauu auguaucaaa uaaagguguc gacaccguau caguaggcaa uacacuauac     1380

uauguaaaua aacaagaagg acaaucacuc uacgucaaag gugaaccaau aauaaacuuc     1440

uacgacccac uuguauuccc aagcgacgaa uuugacgcau caauaagcca aguaaacgaa     1500

aaaauaaacc aaucacuagc auucaucaga aaaucagacg aacuacucca caauguaaau     1560

gcaggaaaau caacaaccaa uaucaugaua acaaccauaa uaauagucau aauaguaaua     1620

cuauuauccc ucauagccgu uggacuacuc cuauauugua aagcacgaua aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8197
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8197
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaac uccucauccu caaagccaac gccaucacca ccauacucac cgcaguaacc      180

uucugcuucg cauccggcca aaacaucaca gaagaguucu accagaguac cugcuccgcc      240

gucuccaaag gcuaccuugg cgcccuccgu accggguggu acacauccgu caucacaauc      300

gaacucucca acaucaaaga aauaaagugc aacggcacag acgccaaagu aaaacugaua      360

aagcaagaac ucgacaaaua caaaaacgcc guaaccgacc uccagcuacu aaugcaaucc      420

acucccgcca ccggcagcgg auccgccauc gccuccggag uagccgucug uaaagucuua      480

caccucgaag gcgaagugaa caaaaucaaa uccgcccuac ucucaaccaa caaagccgua      540

guaucacucu ccgggugcgg cguuucagug cuaacguuca aaguccuuga ccucaaaaac      600

uacaucgaca aacaacuccu ccccauccua aauaaacaau ccugcuccau acccaacauc      660

gagacuguca ucgaguucca gcagaaaaac aaccgacucc ucgaaaucac acgcgaguuc      720

ucugucaacg ccggcgucac aacccccguc uccacauaca ugcucaccaa cagcgaacuc      780

cucucccuaa ucaaugacau gcccaucacc aacgaccaaa agaaacucau gucaaacaac      840

guccaaaucg uccgccaaca auccuacagc aucaugugca ucaucaaaga agaaguucuc      900

gcauacguag uacaacuccc ccucuacgga gugaucgaca cccccugcug gaaacuacac      960

accagcccgc uuugcaccac aaacaccaag gaaggcucca acaucugccu cacucgaacc     1020

gaccgcggcu gguacugcga caacgcaggc uccgucaguu ucuuucccca agcagaaaca     1080

ugcaaagucc aauccaaccg aguauucugc gacaccauga acucccucac ccuaccaucc     1140

gaaguuaacc uaugcaacgu ggacaucuuc aaccccaagu acgacugcaa aauuaugacc     1200

uccaaaaccg acguauccuc cagcgucauc accagccucg gagcaauagu cuccugcuac     1260

ggcaagacca agugcaccgc uuccaacaag ugucgcggaa ucaucaaaac cuucucaaac     1320

ggcugcgacu acgucuccaa caaaggcguc gacaccguau ccguaggaaa cacccuauac     1380

uacgucaaca aacaagaagg acaaucccuc uaugucaaag gcgaacccau caucaauuuc     1440

uacgaccccc uagucuuccc uuccgacgag uucgacgcgu ccaucagcca agucaaugaa     1500

aagaucaacc agagccuggc auucauccgc aaauccgacg aacuccucca caacgucaac     1560

gcgggaaaau ccacgacaaa caucaugauc accaccauca ucaucgucau cauagucauu     1620

cuccuuucuc ucaucgccgu gggacuacuu cucuacugca aagcccgaua aggacuagua     1680

auaaggaaac uguaugaaug ucugugggca ggaagugaag agauccuucu guaaagguuu     1740

uuggaauuau gucugcugaa uaauaaacuu uuuugaaaua auaaaucugg uagaaaaaug     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8198
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8198
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8199
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8199
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccggugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8200
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8200
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8201
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8201
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8202
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8202
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8203
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8203
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaugagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8204
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8204
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauugaaa      120

gccaacgcaa ucacaacaau acuaaccgcc guaacauuuu gcuucgcguc aggccaaaau      180

auaacagaag aauuuuacca aucaacaugc uccgccguau caaaaggaua ccuaggugca      240

uuacgaaccg guugguacac aucaguaauc acaauagaac uuuccaacau uaaagaaaua      300

aaaugcaaug gcacagacgc aaaagucaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgccguca cagacuuaca acuauuaaug caaagcacac cagcaacagg auccggauca      420

gcaauagcau caggaguagc cgucuguaaa guacuacacc uagaaggcga aguuaauaaa      480

auuaaaucag cuuuauuauc aaccaacaaa gcaguaguau cacuauccgg augcggaguc      540

uccguccuaa cauucaaagu acuagaccuc aagaauuaca uagauaaaca acuacuacca      600

auacucaaca aacaaucaug uucaauacca aacaucgaaa ccgucauaga auuucaacaa      660

aaaaauaaua gacucuuaga aauaacacga gaauuuagcg uaaacgcagg agucacaacc      720

ccugucucaa cauacaugcu aaccaauucc gaauuauuau cacucauaaa ugacaugcca      780

auaacuaaug accaaaaaaa acuuauguca aacaacguac aaauaguaag acaacaauca      840

uauucaauaa ugugcauaau caaagaagaa guuuuagcau auguaguaca acuaccacua      900

uauggcguca uagacacacc augcuggaaa uuacacacau caccucuaug cacaacaaac      960

acaaaagaag gaagcaacau uugccuaacc agaaccgaua gaggauggua cugcgauaac     1020

gcaggcucag uaucauucuu cccucaagcc gaaacuugca aaguccaauc aaauagaguc     1080

uucugcgaua caaugaacuc cuuaacuuua ccaucagaag uaaaucuaug caacguagau     1140

aucuuuaauc caaaauacga uugcaaaauc augacaucaa aaacagaugu aucaucuagu     1200

guaauuaccu cccuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccucu     1260

aacaaauguc guggaauaau aaaaacauuc ucaaacggau gcgauuaugu aucaaauaaa     1320

ggugucgaca ccguaucagu aggcaauaca cuauacuaug uaaauaaaca agaaggacaa     1380

ucacucuacg ucaaagguga accaauaaua aacuucuacg acccacuugu auucccaagc     1440

gacgaauuug acgcaucaau aagccaagua aacgaaaaaa uaaaccaauc acuagcauuc     1500

aucagaaaau cagacgaacu acuccacaau guaaaugcag gaaaaucaac aaccaauauc     1560

augauaacaa ccauaauaau agucauaaua guaauacuau uaucccucau agccguugga     1620

cuacuccuau auuguaaagc acgauaagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8205
<211>  1910
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8205
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca ucaccaccau acucaccgca guaaccuucu gcuucgcauc cggccaaaac      180

aucacagaag aguucuacca gaguaccugc uccgccgucu ccaaaggcua ccuuggcgcc      240

cuccguaccg ggugguacac auccgucauc acaaucgaac ucuccaacau caaagaaaua      300

aagugcaacg gcacagacgc caaaguaaaa cugauaaagc aagaacucga caaauacaaa      360

aacgccguaa ccgaccucca gcuacuaaug caauccacuc ccgccaccgg cagcggaucc      420

gccaucgccu ccggaguagc cgucuguaaa gucuuacacc ucgaaggcga agugaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gccguaguau cacucuccgg gugcggcguu      540

ucagugcuaa cguucaaagu ccuugaccuc aaaaacuaca ucgacaaaca acuccucccc      600

auccuaaaua aacaauccug cuccauaccc aacaucgaga cugucaucga guuccagcag      660

aaaaacaacc gacuccucga aaucacacgc gaguucucug ucaacgccgg cgucacaacc      720

cccgucucca cauacaugcu caccaacagc gaacuccucu cccuaaucaa ugacaugccc      780

aucaccaacg accaaaagaa acucauguca aacaacgucc aaaucguccg ccaacaaucc      840

uacagcauca ugugcaucau caaagaagaa guucucgcau acguaguaca acucccccuc      900

uacggaguga ucgacacccc cugcuggaaa cuacacacca gcccgcuuug caccacaaac      960

accaaggaag gcuccaacau cugccucacu cgaaccgacc gcggcuggua cugcgacaac     1020

gcaggcuccg ucaguuucuu uccccaagca gaaacaugca aaguccaauc caaccgagua     1080

uucugcgaca ccaugaacuc ccucacccua ccauccgaag uuaaccuaug caacguggac     1140

aucuucaacc ccaaguacga cugcaaaauu augaccucca aaaccgacgu auccuccagc     1200

gucaucacca gccucggagc aauagucucc ugcuacggca agaccaagug caccgcuucc     1260

aacaaguguc gcggaaucau caaaaccuuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca ccguauccgu aggaaacacc cuauacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccaucauc aauuucuacg acccccuagu cuucccuucc     1440

gacgaguucg acgcguccau cagccaaguc aaugaaaaga ucaaccagag ccuggcauuc     1500

auccgcaaau ccgacgaacu ccuccacaac gucaacgcgg gaaaauccac gacaaacauc     1560

augaucacca ccaucaucau cgucaucaua gucauucucc uuucucucau cgccguggga     1620

cuacuucucu acugcaaagc ccgauaagga cuaguaauaa ggaaacugua ugaaugucug     1680

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau     1740

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1860

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1910


<210>  8206
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8206
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8207
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8207
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccggugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8208
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8208
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8209
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8209
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8210
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8210
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8211
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8211
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaugagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8212
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8212
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauugaaa      120

gccaacgcaa ucacaacaau acuaaccgcc guaacauuuu gcuucgcguc aggccaaaau      180

auaacagaag aauuuuacca aucaacaugc uccgccguau caaaaggaua ccuaggugca      240

uuacgaaccg guugguacac aucaguaauc acaauagaac uuuccaacau uaaagaaaua      300

aaaugcaaug gcacagacgc aaaagucaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgccguca cagacuuaca acuauuaaug caaagcacac cagcaacagg auccggauca      420

gcaauagcau caggaguagc cgucuguaaa guacuacacc uagaaggcga aguuaauaaa      480

auuaaaucag cuuuauuauc aaccaacaaa gcaguaguau cacuauccgg augcggaguc      540

uccguccuaa cauucaaagu acuagaccuc aagaauuaca uagauaaaca acuacuacca      600

auacucaaca aacaaucaug uucaauacca aacaucgaaa ccgucauaga auuucaacaa      660

aaaaauaaua gacucuuaga aauaacacga gaauuuagcg uaaacgcagg agucacaacc      720

ccugucucaa cauacaugcu aaccaauucc gaauuauuau cacucauaaa ugacaugcca      780

auaacuaaug accaaaaaaa acuuauguca aacaacguac aaauaguaag acaacaauca      840

uauucaauaa ugugcauaau caaagaagaa guuuuagcau auguaguaca acuaccacua      900

uauggcguca uagacacacc augcuggaaa uuacacacau caccucuaug cacaacaaac      960

acaaaagaag gaagcaacau uugccuaacc agaaccgaua gaggauggua cugcgauaac     1020

gcaggcucag uaucauucuu cccucaagcc gaaacuugca aaguccaauc aaauagaguc     1080

uucugcgaua caaugaacuc cuuaacuuua ccaucagaag uaaaucuaug caacguagau     1140

aucuuuaauc caaaauacga uugcaaaauc augacaucaa aaacagaugu aucaucuagu     1200

guaauuaccu cccuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccucu     1260

aacaaauguc guggaauaau aaaaacauuc ucaaacggau gcgauuaugu aucaaauaaa     1320

ggugucgaca ccguaucagu aggcaauaca cuauacuaug uaaauaaaca agaaggacaa     1380

ucacucuacg ucaaagguga accaauaaua aacuucuacg acccacuugu auucccaagc     1440

gacgaauuug acgcaucaau aagccaagua aacgaaaaaa uaaaccaauc acuagcauuc     1500

aucagaaaau cagacgaacu acuccacaau guaaaugcag gaaaaucaac aaccaauauc     1560

augauaacaa ccauaauaau agucauaaua guaauacuau uaucccucau agccguugga     1620

cuacuccuau auuguaaagc acgauaagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8213
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8213
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca ucaccaccau acucaccgca guaaccuucu gcuucgcauc cggccaaaac      180

aucacagaag aguucuacca gaguaccugc uccgccgucu ccaaaggcua ccuuggcgcc      240

cuccguaccg ggugguacac auccgucauc acaaucgaac ucuccaacau caaagaaaua      300

aagugcaacg gcacagacgc caaaguaaaa cugauaaagc aagaacucga caaauacaaa      360

aacgccguaa ccgaccucca gcuacuaaug caauccacuc ccgccaccgg cagcggaucc      420

gccaucgccu ccggaguagc cgucuguaaa gucuuacacc ucgaaggcga agugaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gccguaguau cacucuccgg gugcggcguu      540

ucagugcuaa cguucaaagu ccuugaccuc aaaaacuaca ucgacaaaca acuccucccc      600

auccuaaaua aacaauccug cuccauaccc aacaucgaga cugucaucga guuccagcag      660

aaaaacaacc gacuccucga aaucacacgc gaguucucug ucaacgccgg cgucacaacc      720

cccgucucca cauacaugcu caccaacagc gaacuccucu cccuaaucaa ugacaugccc      780

aucaccaacg accaaaagaa acucauguca aacaacgucc aaaucguccg ccaacaaucc      840

uacagcauca ugugcaucau caaagaagaa guucucgcau acguaguaca acucccccuc      900

uacggaguga ucgacacccc cugcuggaaa cuacacacca gcccgcuuug caccacaaac      960

accaaggaag gcuccaacau cugccucacu cgaaccgacc gcggcuggua cugcgacaac     1020

gcaggcuccg ucaguuucuu uccccaagca gaaacaugca aaguccaauc caaccgagua     1080

uucugcgaca ccaugaacuc ccucacccua ccauccgaag uuaaccuaug caacguggac     1140

aucuucaacc ccaaguacga cugcaaaauu augaccucca aaaccgacgu auccuccagc     1200

gucaucacca gccucggagc aauagucucc ugcuacggca agaccaagug caccgcuucc     1260

aacaaguguc gcggaaucau caaaaccuuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca ccguauccgu aggaaacacc cuauacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccaucauc aauuucuacg acccccuagu cuucccuucc     1440

gacgaguucg acgcguccau cagccaaguc aaugaaaaga ucaaccagag ccuggcauuc     1500

auccgcaaau ccgacgaacu ccuccacaac gucaacgcgg gaaaauccac gacaaacauc     1560

augaucacca ccaucaucau cgucaucaua gucauucucc uuucucucau cgccguggga     1620

cuacuucucu acugcaaagc ccgauaagga cuaguacugg cugcaucucc cuuuccucug     1680

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca     1740

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1920

agaauu                                                                1926


<210>  8214
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8214
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8215
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8215
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccggugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8216
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8216
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8217
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8217
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8218
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8218
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8219
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8219
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaugagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8220
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8220
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauugaaa      120

gccaacgcaa ucacaacaau acuaaccgcc guaacauuuu gcuucgcguc aggccaaaau      180

auaacagaag aauuuuacca aucaacaugc uccgccguau caaaaggaua ccuaggugca      240

uuacgaaccg guugguacac aucaguaauc acaauagaac uuuccaacau uaaagaaaua      300

aaaugcaaug gcacagacgc aaaagucaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgccguca cagacuuaca acuauuaaug caaagcacac cagcaacagg auccggauca      420

gcaauagcau caggaguagc cgucuguaaa guacuacacc uagaaggcga aguuaauaaa      480

auuaaaucag cuuuauuauc aaccaacaaa gcaguaguau cacuauccgg augcggaguc      540

uccguccuaa cauucaaagu acuagaccuc aagaauuaca uagauaaaca acuacuacca      600

auacucaaca aacaaucaug uucaauacca aacaucgaaa ccgucauaga auuucaacaa      660

aaaaauaaua gacucuuaga aauaacacga gaauuuagcg uaaacgcagg agucacaacc      720

ccugucucaa cauacaugcu aaccaauucc gaauuauuau cacucauaaa ugacaugcca      780

auaacuaaug accaaaaaaa acuuauguca aacaacguac aaauaguaag acaacaauca      840

uauucaauaa ugugcauaau caaagaagaa guuuuagcau auguaguaca acuaccacua      900

uauggcguca uagacacacc augcuggaaa uuacacacau caccucuaug cacaacaaac      960

acaaaagaag gaagcaacau uugccuaacc agaaccgaua gaggauggua cugcgauaac     1020

gcaggcucag uaucauucuu cccucaagcc gaaacuugca aaguccaauc aaauagaguc     1080

uucugcgaua caaugaacuc cuuaacuuua ccaucagaag uaaaucuaug caacguagau     1140

aucuuuaauc caaaauacga uugcaaaauc augacaucaa aaacagaugu aucaucuagu     1200

guaauuaccu cccuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccucu     1260

aacaaauguc guggaauaau aaaaacauuc ucaaacggau gcgauuaugu aucaaauaaa     1320

ggugucgaca ccguaucagu aggcaauaca cuauacuaug uaaauaaaca agaaggacaa     1380

ucacucuacg ucaaagguga accaauaaua aacuucuacg acccacuugu auucccaagc     1440

gacgaauuug acgcaucaau aagccaagua aacgaaaaaa uaaaccaauc acuagcauuc     1500

aucagaaaau cagacgaacu acuccacaau guaaaugcag gaaaaucaac aaccaauauc     1560

augauaacaa ccauaauaau agucauaaua guaauacuau uaucccucau agccguugga     1620

cuacuccuau auuguaaagc acgauaagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8221
<211>  2142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8221
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca ucaccaccau acucaccgca guaaccuucu gcuucgcauc cggccaaaac      180

aucacagaag aguucuacca gaguaccugc uccgccgucu ccaaaggcua ccuuggcgcc      240

cuccguaccg ggugguacac auccgucauc acaaucgaac ucuccaacau caaagaaaua      300

aagugcaacg gcacagacgc caaaguaaaa cugauaaagc aagaacucga caaauacaaa      360

aacgccguaa ccgaccucca gcuacuaaug caauccacuc ccgccaccgg cagcggaucc      420

gccaucgccu ccggaguagc cgucuguaaa gucuuacacc ucgaaggcga agugaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gccguaguau cacucuccgg gugcggcguu      540

ucagugcuaa cguucaaagu ccuugaccuc aaaaacuaca ucgacaaaca acuccucccc      600

auccuaaaua aacaauccug cuccauaccc aacaucgaga cugucaucga guuccagcag      660

aaaaacaacc gacuccucga aaucacacgc gaguucucug ucaacgccgg cgucacaacc      720

cccgucucca cauacaugcu caccaacagc gaacuccucu cccuaaucaa ugacaugccc      780

aucaccaacg accaaaagaa acucauguca aacaacgucc aaaucguccg ccaacaaucc      840

uacagcauca ugugcaucau caaagaagaa guucucgcau acguaguaca acucccccuc      900

uacggaguga ucgacacccc cugcuggaaa cuacacacca gcccgcuuug caccacaaac      960

accaaggaag gcuccaacau cugccucacu cgaaccgacc gcggcuggua cugcgacaac     1020

gcaggcuccg ucaguuucuu uccccaagca gaaacaugca aaguccaauc caaccgagua     1080

uucugcgaca ccaugaacuc ccucacccua ccauccgaag uuaaccuaug caacguggac     1140

aucuucaacc ccaaguacga cugcaaaauu augaccucca aaaccgacgu auccuccagc     1200

gucaucacca gccucggagc aauagucucc ugcuacggca agaccaagug caccgcuucc     1260

aacaaguguc gcggaaucau caaaaccuuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca ccguauccgu aggaaacacc cuauacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccaucauc aauuucuacg acccccuagu cuucccuucc     1440

gacgaguucg acgcguccau cagccaaguc aaugaaaaga ucaaccagag ccuggcauuc     1500

auccgcaaau ccgacgaacu ccuccacaac gucaacgcgg gaaaauccac gacaaacauc     1560

augaucacca ccaucaucau cgucaucaua gucauucucc uuucucucau cgccguggga     1620

cuacuucucu acugcaaagc ccgauaagga cuagugaagg gaacacccaa auuuaauuca     1680

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca     1740

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1800

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1860

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1920

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1980

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2100

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2142


<210>  8222
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8222
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcggaccg gcugguacac cuccgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg ggaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug caguccaccc cggcaaccgg cuccggcucc      420

gccaucgcga gcggcgucgc cgugugcaag gugcugcacc ucgaggggga ggucaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguga gccucuccgg cugcggcguc      540

agcgugcuga ccuucaaggu gcuggaccuc aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cuccaucccc aacaucgaga cggugaucga guuccagcag      660

aagaacaacc ggcuccugga gaucacccgc gaguucagcg ugaacgccgg ggucaccacc      720

cccgugucca cguacaugcu gaccaacagc gagcuccugu cccugaucaa cgacaugccg      780

aucaccaacg accagaagaa gcucaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggcgu acguggucca gcugccccuc      900

uacggcguga ucgacacccc cugcuggaag cugcacacga gcccccugug caccaccaac      960

accaaggagg gguccaacau cugccucacg cgcaccgacc ggggcuggua cugcgacaac     1020

gccggcagcg ucuccuucuu cccgcaggcc gagaccugca aggugcagag caaccgcgug     1080

uucugcgaca ccaugaacuc ccugacgcug cccagcgagg uaaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu gagcuccagc     1200

gugaucaccu cccugggggc caucgucagc ugcuacggca agacgaagug caccgccagc     1260

aacaagugcc gggggaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccguguccgu cgggaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccucuacg ugaaggggga gcccaucauc aacuucuacg acccgcuggu cuuccccucc     1440

gacgaguucg acgcgagcau cucccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

auccgcaagu ccgacgagcu gcuccacaac gugaacgccg gcaagagcac gaccaacauc     1560

augaucacca ccaucaucau cgucaucauc gugauccugc ugucccucau cgccgugggg     1620

cugcugcucu acugcaaggc ccggugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8223
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8223
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcca ucaccaccau ccugacggcg gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca guccacgugc agcgccgucu ccaaggggua ccucggcgcc      240

cugcgcaccg ggugguacac cagcgugauc accaucgagc uguccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cucaucaagc aggagcugga caaguacaag      360

aacgcgguca cggaccugca gcuccugaug cagagcaccc ccgccaccgg guccggcagc      420

gccaucgccu ccggcguggc ggugugcaag guccugcacc ucgaggggga ggugaacaag      480

aucaagagcg cccugcuguc caccaacaag gccgugguca gccucuccgg cugcggggug      540

agcgugcuga cguucaaggu ccuggaccuc aagaacuaca ucgacaagca gcugcugccg      600

auccucaaca agcaguccug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaacc ggcugcugga gaucacccgc gaguucuccg ugaacgccgg cgucaccacg      720

cccgugagca ccuacaugcu caccaacucc gagcugcuga gccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucguccg gcagcagucc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggucca gcucccgcug      900

uacgggguga ucgacacgcc cugcuggaag cugcacacca gcccccucug caccaccaac      960

acgaaggagg gcuccaacau cugccugacc cgcaccgacc ggggcuggua cugcgacaac     1020

gcgggguccg ugagcuucuu cccccaggcc gagaccugca agguccaguc caaccgcgug     1080

uucugcgaca cgaugaacag ccugacccuc ccguccgagg ucaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu guccagcucc     1200

gucaucacga gccugggcgc caucgugucc ugcuacggga agaccaagug caccgccagc     1260

aacaagugcc ggggcaucau caagaccuuc uccaacggcu gcgacuacgu gagcaacaag     1320

ggggucgaca cgguguccgu gggcaacacc cucuacuacg ucaacaagca ggaggggcag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guucccgagc     1440

gacgaguucg acgccuccau cagccagguc aacgagaaga ucaaccaguc ccucgcguuc     1500

auccgcaaga gcgacgagcu gcugcacaac gugaacgccg ggaaguccac caccaacauc     1560

augaucacca cgaucaucau cgugaucauc gucauccucc ugagccugau cgccgugggc     1620

cuccugcugu acugcaaggc ccggugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8224
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8224
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcuccu cauccucaag      120

gccaacgcca ucaccaccau ccucaccgcc gucaccuucu gcuucgccuc cggccagaac      180

aucaccgagg aguucuacca guccaccugc uccgccgucu ccaagggcua ccucggcgcc      240

cuccgcaccg gcugguacac cuccgucauc accaucgagc ucuccaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggucaag cucaucaagc aggagcucga caaguacaag      360

aacgccguca ccgaccucca gcuccucaug caguccaccc ccgccaccgg cuccggcucc      420

gccaucgccu ccggcgucgc cgucugcaag guccuccacc ucgagggcga ggucaacaag      480

aucaaguccg cccuccucuc caccaacaag gccgucgucu cccucuccgg cugcggcguc      540

uccguccuca ccuucaaggu ccucgaccuc aagaacuaca ucgacaagca gcuccucccc      600

auccucaaca agcaguccug cuccaucccc aacaucgaga ccgucaucga guuccagcag      660

aagaacaacc gccuccucga gaucacccgc gaguucuccg ucaacgccgg cgucaccacc      720

cccgucucca ccuacaugcu caccaacucc gagcuccucu cccucaucaa cgacaugccc      780

aucaccaacg accagaagaa gcucaugucc aacaacgucc agaucguccg ccagcagucc      840

uacuccauca ugugcaucau caaggaggag guccucgccu acgucgucca gcucccccuc      900

uacggcguca ucgacacccc cugcuggaag cuccacaccu ccccccucug caccaccaac      960

accaaggagg gcuccaacau cugccucacc cgcaccgacc gcggcuggua cugcgacaac     1020

gccggcuccg ucuccuucuu cccccaggcc gagaccugca agguccaguc caaccgcguc     1080

uucugcgaca ccaugaacuc ccucacccuc cccuccgagg ucaaccucug caacgucgac     1140

aucuucaacc ccaaguacga cugcaagauc augaccucca agaccgacgu cuccuccucc     1200

gucaucaccu cccucggcgc caucgucucc ugcuacggca agaccaagug caccgccucc     1260

aacaagugcc gcggcaucau caagaccuuc uccaacggcu gcgacuacgu cuccaacaag     1320

ggcgucgaca ccgucuccgu cggcaacacc cucuacuacg ucaacaagca ggagggccag     1380

ucccucuacg ucaagggcga gcccaucauc aacuucuacg acccccucgu cuuccccucc     1440

gacgaguucg acgccuccau cucccagguc aacgagaaga ucaaccaguc ccucgccuuc     1500

auccgcaagu ccgacgagcu ccuccacaac gucaacgccg gcaaguccac caccaacauc     1560

augaucacca ccaucaucau cgucaucauc gucauccucc ucucccucau cgccgucggc     1620

cuccuccucu acugcaaggc ccgcugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8225
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8225
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccuuaag      120

gccaacgcua uuaccacaau acugacugca gugacguucu gcuuugccag cggccagaau      180

aucaccgaag aguucuacca auccacaugu ucugcggucu caaaagggua uuugggagcu      240

uuaagaacug guugguacac caguguuauu acaaucgaac ugagcaacau uaaggagauc      300

aaaugcaaug gcaccgacgc caaggugaaa cuaauaaagc aggaacucga uaaguauaaa      360

aacgcaguaa cugaccugca gcuucugaug caguccacac ccgccaccgg gucuggaucg      420

gcuaucgcau caggcguggc cgucuguaag guguugcacc ucgaggguga gguuaauaaa      480

auuaagagcg cucugcugag uacgaacaaa gccguggucu cccucucugg gugcggagug      540

agcguauuaa cuuuuaaggu ucuggaucuu aagaauuaca ucgacaaaca auugcugccu      600

auucuaaaca agcaguccug uucaauccca aauauagaaa ccgugauuga guuccagcag      660

aaaaacaaua ggcuccugga aaucacacgg gaguuuagug ucaacgcggg cgugacuacc      720

ccggugagca cauauaugcu uaccaauucu gagcuguugu cccucauuaa cgauaugccc      780

aucacgaaug accaaaagaa acugauguca aacaacgucc agaucguucg ccagcagagc      840

uacaguauua ugugcauaau caaggaagag guguuagcau auguagugca acugccucuc      900

uacggcguca uugauacucc auguuggaaa cuucauacau cuccccugug caccacuaau      960

acaaaggaag gguccaacau cuguuugacc cgaacggacc guggauggua cugcgauaau     1020

gccgguagcg ugucguucuu uccucaggcu gagaccugua agguucaguc uaacagagug     1080

uucugcgaca caaugaacuc ccuaacucug ccaucagaag ucaaucucug caauguggau     1140

auauuuaacc ccaaauauga cuguaagauu augaccagua aaacagaugu aagcuccucu     1200

guuaucacua gccugggcgc caucguguca ugcuacggga agaccaaaug uacagcaagu     1260

aauaagugca ggggaauuau caagaccuuc uccaacggcu gugacuaugu cagcaauaaa     1320

gguguggaca cugucucugu ggggaacacg cuuuacuaug uuaauaagca agagggacag     1380

ucacuguacg ugaaaggcga gccuauuaua aacuuuuaug auccauuggu auucccgagu     1440

gacgaauuug augcuagcau cucccagguc aaugagaaga uuaaccaguc ucucgccuuc     1500

auccggaaau cggacgaacu guuacacaac gugaaugcgg gcaagagcac aaccaacauc     1560

augauuacua ccauaaucau uguuaucauu gugauccugc uaucccucau agccgucggg     1620

cugcuuuugu acugcaaggc acgcugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8226
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8226
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu gauccugaag      120

gccaacgcca ucaccaccau ccugaccgcc gugaccuucu gcuucgccag cggccagaac      180

aucaccgagg aguucuacca gagcaccugc agcgccguga gcaagggcua ccugggcgcc      240

cugagaaccg gcugguacac cagcgugauc accaucgagc ugagcaacau caaggagauc      300

aagugcaacg gcaccgacgc caaggugaag cugaucaagc aggagcugga caaguacaag      360

aacgccguga ccgaccugca gcugcugaug cagagcaccc ccgccaccgg cagcggcagc      420

gccaucgcca gcggcguggc cgugugcaag gugcugcacc uggagggcga ggugaacaag      480

aucaagagcg cccugcugag caccaacaag gccgugguga gccugagcgg cugcggcgug      540

agcgugcuga ccuucaaggu gcuggaccug aagaacuaca ucgacaagca gcugcugccc      600

auccugaaca agcagagcug cagcaucccc aacaucgaga ccgugaucga guuccagcag      660

aagaacaaca gacugcugga gaucaccaga gaguucagcg ugaacgccgg cgugaccacc      720

cccgugagca ccuacaugcu gaccaacagc gagcugcuga gccugaucaa cgacaugccc      780

aucaccaacg accagaagaa gcugaugagc aacaacgugc agaucgugag acagcagagc      840

uacagcauca ugugcaucau caaggaggag gugcuggccu acguggugca gcugccccug      900

uacggcguga ucgacacccc cugcuggaag cugcacacca gcccccugug caccaccaac      960

accaaggagg gcagcaacau cugccugacc agaaccgaca gaggcuggua cugcgacaac     1020

gccggcagcg ugagcuucuu cccccaggcc gagaccugca aggugcagag caacagagug     1080

uucugcgaca ccaugaacag ccugacccug cccagcgagg ugaaccugug caacguggac     1140

aucuucaacc ccaaguacga cugcaagauc augaccagca agaccgacgu gagcagcagc     1200

gugaucacca gccugggcgc caucgugagc ugcuacggca agaccaagug caccgccagc     1260

aacaagugca gaggcaucau caagaccuuc agcaacggcu gcgacuacgu gagcaacaag     1320

ggcguggaca ccgugagcgu gggcaacacc cuguacuacg ugaacaagca ggagggccag     1380

agccuguacg ugaagggcga gcccaucauc aacuucuacg acccccuggu guuccccagc     1440

gacgaguucg acgccagcau cagccaggug aacgagaaga ucaaccagag ccuggccuuc     1500

aucagaaaga gcgacgagcu gcugcacaac gugaacgccg gcaagagcac caccaacauc     1560

augaucacca ccaucaucau cgugaucauc gugauccugc ugagccugau cgccgugggc     1620

cugcugcugu acugcaaggc cagaugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8227
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8227
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagcugcu cauccugaag      120

gccaacgcua uuaccacaau ccuuacggcc gugaccuucu gcuuugcgag cggccagaau      180

auuacagaag aguucuacca auccaccugu ucugcuguca gcaaagggua ucugggagcc      240

cucagaacag gcugguacac cuccguuauc acaauugaac ugucuaacau caaggagauc      300

aaaugcaaug ggaccgacgc caaggugaaa cuuauuaagc aggaacugga uaaguauaaa      360

aacgcuguga cggaccucca gcugcugaug cagagcaccc ccgccacagg auccggcucu      420

gcuaucgcca gcggggucgc gguguguaag guucuccacc uggagggaga ggugaauaaa      480

auuaaguccg cccuucugag caccaacaaa gcugucgugu cucucuccgg cugcggcguu      540

agcgugcuga cauuuaaggu ccuugaucug aagaauuaca ucgacaaaca acuccugccu      600

auucugaaca agcagucuug uuccaucccg aauauugaaa ccgugaucga guuccagcag      660

aaaaacaauc ggcuccugga aaucacgcgc gaguuuagcg ugaacgccgg ggucacaacc      720

cccguuucua cauauaugcu uaccaauucc gagcugcuca gccugauuaa cgauaugccu      780

aucaccaaug accaaaagaa acuuaugucc aacaacgugc agauugugag acagcagucu      840

uacagcauca ugugcauuau caaggaagag guccuggcuu augugguuca acucccccug      900

uacggaguga ucgauacacc uuguuggaaa cugcauacga gcccccucug caccacaaau      960

accaaggaag gcagcaacau uugucugaca cggaccgacc gcggguggua cugcgauaau     1020

gccggaucug ucuccuucuu uccucaggcg gagacgugua aggugcagag caacagaguu     1080

uucugcgaca caaugaacuc ucuuacccug ccgagcgaag ugaaucucug caaugucgau     1140

aucuuuaacc ccaaauauga cuguaagauu augaccucca aaacagaugu gucuagcucc     1200

gucaucacca gccugggcgc cauugugucu ugcuacggga agacaaaaug uacggcuucc     1260

aauaagugcc ggggaaucau caagaccuuc agcaacggcu gugacuaugu uucuaauaaa     1320

ggcguggaca cagucuccgu ggggaacacc cuuuacuaug uuaauaagca agagggacag     1380

agccuguacg ugaaaggcga gccuauuauc aacuuuuaug auccccucgu cuucccuucc     1440

gacgaauuug augccucuau uagccaggug aaugagaaga ucaaccaguc ccuggcuuuc     1500

auucgcaaau cugacgaacu gcuccacaac gugaaugccg ggaaguccac aaccaacauc     1560

augauuacga ccaucaucau uguuaucauu gucauccugc uuucccugau ugccguggga     1620

cuccugcugu acugcaaggc uagaugagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8228
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8228
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuacu cauauugaaa      120

gccaacgcaa ucacaacaau acuaaccgcc guaacauuuu gcuucgcguc aggccaaaau      180

auaacagaag aauuuuacca aucaacaugc uccgccguau caaaaggaua ccuaggugca      240

uuacgaaccg guugguacac aucaguaauc acaauagaac uuuccaacau uaaagaaaua      300

aaaugcaaug gcacagacgc aaaagucaaa cuaauaaaac aagaacuaga caaauauaaa      360

aacgccguca cagacuuaca acuauuaaug caaagcacac cagcaacagg auccggauca      420

gcaauagcau caggaguagc cgucuguaaa guacuacacc uagaaggcga aguuaauaaa      480

auuaaaucag cuuuauuauc aaccaacaaa gcaguaguau cacuauccgg augcggaguc      540

uccguccuaa cauucaaagu acuagaccuc aagaauuaca uagauaaaca acuacuacca      600

auacucaaca aacaaucaug uucaauacca aacaucgaaa ccgucauaga auuucaacaa      660

aaaaauaaua gacucuuaga aauaacacga gaauuuagcg uaaacgcagg agucacaacc      720

ccugucucaa cauacaugcu aaccaauucc gaauuauuau cacucauaaa ugacaugcca      780

auaacuaaug accaaaaaaa acuuauguca aacaacguac aaauaguaag acaacaauca      840

uauucaauaa ugugcauaau caaagaagaa guuuuagcau auguaguaca acuaccacua      900

uauggcguca uagacacacc augcuggaaa uuacacacau caccucuaug cacaacaaac      960

acaaaagaag gaagcaacau uugccuaacc agaaccgaua gaggauggua cugcgauaac     1020

gcaggcucag uaucauucuu cccucaagcc gaaacuugca aaguccaauc aaauagaguc     1080

uucugcgaua caaugaacuc cuuaacuuua ccaucagaag uaaaucuaug caacguagau     1140

aucuuuaauc caaaauacga uugcaaaauc augacaucaa aaacagaugu aucaucuagu     1200

guaauuaccu cccuaggagc aauaguaagc ugcuacggaa aaacaaaaug caccgccucu     1260

aacaaauguc guggaauaau aaaaacauuc ucaaacggau gcgauuaugu aucaaauaaa     1320

ggugucgaca ccguaucagu aggcaauaca cuauacuaug uaaauaaaca agaaggacaa     1380

ucacucuacg ucaaagguga accaauaaua aacuucuacg acccacuugu auucccaagc     1440

gacgaauuug acgcaucaau aagccaagua aacgaaaaaa uaaaccaauc acuagcauuc     1500

aucagaaaau cagacgaacu acuccacaau guaaaugcag gaaaaucaac aaccaauauc     1560

augauaacaa ccauaauaau agucauaaua guaauacuau uaucccucau agccguugga     1620

cuacuccuau auuguaaagc acgauaagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8229
<211>  1922
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8229
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaacuccu cauccucaaa      120

gccaacgcca ucaccaccau acucaccgca guaaccuucu gcuucgcauc cggccaaaac      180

aucacagaag aguucuacca gaguaccugc uccgccgucu ccaaaggcua ccuuggcgcc      240

cuccguaccg ggugguacac auccgucauc acaaucgaac ucuccaacau caaagaaaua      300

aagugcaacg gcacagacgc caaaguaaaa cugauaaagc aagaacucga caaauacaaa      360

aacgccguaa ccgaccucca gcuacuaaug caauccacuc ccgccaccgg cagcggaucc      420

gccaucgccu ccggaguagc cgucuguaaa gucuuacacc ucgaaggcga agugaacaaa      480

aucaaauccg cccuacucuc aaccaacaaa gccguaguau cacucuccgg gugcggcguu      540

ucagugcuaa cguucaaagu ccuugaccuc aaaaacuaca ucgacaaaca acuccucccc      600

auccuaaaua aacaauccug cuccauaccc aacaucgaga cugucaucga guuccagcag      660

aaaaacaacc gacuccucga aaucacacgc gaguucucug ucaacgccgg cgucacaacc      720

cccgucucca cauacaugcu caccaacagc gaacuccucu cccuaaucaa ugacaugccc      780

aucaccaacg accaaaagaa acucauguca aacaacgucc aaaucguccg ccaacaaucc      840

uacagcauca ugugcaucau caaagaagaa guucucgcau acguaguaca acucccccuc      900

uacggaguga ucgacacccc cugcuggaaa cuacacacca gcccgcuuug caccacaaac      960

accaaggaag gcuccaacau cugccucacu cgaaccgacc gcggcuggua cugcgacaac     1020

gcaggcuccg ucaguuucuu uccccaagca gaaacaugca aaguccaauc caaccgagua     1080

uucugcgaca ccaugaacuc ccucacccua ccauccgaag uuaaccuaug caacguggac     1140

aucuucaacc ccaaguacga cugcaaaauu augaccucca aaaccgacgu auccuccagc     1200

gucaucacca gccucggagc aauagucucc ugcuacggca agaccaagug caccgcuucc     1260

aacaaguguc gcggaaucau caaaaccuuc ucaaacggcu gcgacuacgu cuccaacaaa     1320

ggcgucgaca ccguauccgu aggaaacacc cuauacuacg ucaacaaaca agaaggacaa     1380

ucccucuaug ucaaaggcga acccaucauc aauuucuacg acccccuagu cuucccuucc     1440

gacgaguucg acgcguccau cagccaaguc aaugaaaaga ucaaccagag ccuggcauuc     1500

auccgcaaau ccgacgaacu ccuccacaac gucaacgcgg gaaaauccac gacaaacauc     1560

augaucacca ccaucaucau cgucaucaua gucauucucc uuucucucau cgccguggga     1620

cuacuucucu acugcaaagc ccgauaagga cuaguggaag cauuuuccug gcugauuaaa     1680

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac     1740

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1860

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1920

uu                                                                    1922


<210>  8230
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8230
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8231
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8231
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8232
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8232
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8233
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8233
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8234
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8234
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8235
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8235
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagau gaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8236
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8236
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau ugaaagccaa cgcaaucaca acaauacuaa ccgccguaac auuuugcuuc      240

gcgucaggcc aaaauauaac agaagaauuu uaccaaucaa caugcuccgc cguaucaaaa      300

ggauaccuag gugcauuacg aaccgguugg uacacaucag uaaucacaau agaacuuucc      360

aacauuaaag aaauaaaaug caauggcaca gacgcaaaag ucaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc cgucacagac uuacaacuau uaaugcaaag cacaccagca      480

acaggauccg gaucagcaau agcaucagga guagccgucu guaaaguacu acaccuagaa      540

ggcgaaguua auaaaauuaa aucagcuuua uuaucaacca acaaagcagu aguaucacua      600

uccggaugcg gagucuccgu ccuaacauuc aaaguacuag accucaagaa uuacauagau      660

aaacaacuac uaccaauacu caacaaacaa ucauguucaa uaccaaacau cgaaaccguc      720

auagaauuuc aacaaaaaaa uaauagacuc uuagaaauaa cacgagaauu uagcguaaac      780

gcaggaguca caaccccugu cucaacauac augcuaacca auuccgaauu auuaucacuc      840

auaaaugaca ugccaauaac uaaugaccaa aaaaaacuua ugucaaacaa cguacaaaua      900

guaagacaac aaucauauuc aauaaugugc auaaucaaag aagaaguuuu agcauaugua      960

guacaacuac cacuauaugg cgucauagac acaccaugcu ggaaauuaca cacaucaccu     1020

cuaugcacaa caaacacaaa agaaggaagc aacauuugcc uaaccagaac cgauagagga     1080

ugguacugcg auaacgcagg cucaguauca uucuucccuc aagccgaaac uugcaaaguc     1140

caaucaaaua gagucuucug cgauacaaug aacuccuuaa cuuuaccauc agaaguaaau     1200

cuaugcaacg uagauaucuu uaauccaaaa uacgauugca aaaucaugac aucaaaaaca     1260

gauguaucau cuaguguaau uaccucccua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucuaacaa augucgugga auaauaaaaa cauucucaaa cggaugcgau     1380

uauguaucaa auaaaggugu cgacaccgua ucaguaggca auacacuaua cuauguaaau     1440

aaacaagaag gacaaucacu cuacgucaaa ggugaaccaa uaauaaacuu cuacgaccca     1500

cuuguauucc caagcgacga auuugacgca ucaauaagcc aaguaaacga aaaaauaaac     1560

caaucacuag cauucaucag aaaaucagac gaacuacucc acaauguaaa ugcaggaaaa     1620

ucaacaacca auaucaugau aacaaccaua auaauaguca uaauaguaau acuauuaucc     1680

cucauagccg uuggacuacu ccuauauugu aaagcacgau aaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8237
<211>  1985
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8237
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccaucacc accauacuca ccgcaguaac cuucugcuuc      240

gcauccggcc aaaacaucac agaagaguuc uaccagagua ccugcuccgc cgucuccaaa      300

ggcuaccuug gcgcccuccg uaccgggugg uacacauccg ucaucacaau cgaacucucc      360

aacaucaaag aaauaaagug caacggcaca gacgccaaag uaaaacugau aaagcaagaa      420

cucgacaaau acaaaaacgc cguaaccgac cuccagcuac uaaugcaauc cacucccgcc      480

accggcagcg gauccgccau cgccuccgga guagccgucu guaaagucuu acaccucgaa      540

ggcgaaguga acaaaaucaa auccgcccua cucucaacca acaaagccgu aguaucacuc      600

uccgggugcg gcguuucagu gcuaacguuc aaaguccuug accucaaaaa cuacaucgac      660

aaacaacucc uccccauccu aaauaaacaa uccugcucca uacccaacau cgagacuguc      720

aucgaguucc agcagaaaaa caaccgacuc cucgaaauca cacgcgaguu cucugucaac      780

gccggcguca caacccccgu cuccacauac augcucacca acagcgaacu ccucucccua      840

aucaaugaca ugcccaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      900

guccgccaac aauccuacag caucaugugc aucaucaaag aagaaguucu cgcauacgua      960

guacaacucc cccucuacgg agugaucgac acccccugcu ggaaacuaca caccagcccg     1020

cuuugcacca caaacaccaa ggaaggcucc aacaucugcc ucacucgaac cgaccgcggc     1080

ugguacugcg acaacgcagg cuccgucagu uucuuucccc aagcagaaac augcaaaguc     1140

caauccaacc gaguauucug cgacaccaug aacucccuca cccuaccauc cgaaguuaac     1200

cuaugcaacg uggacaucuu caaccccaag uacgacugca aaauuaugac cuccaaaacc     1260

gacguauccu ccagcgucau caccagccuc ggagcaauag ucuccugcua cggcaagacc     1320

aagugcaccg cuuccaacaa gugucgcgga aucaucaaaa ccuucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacaccgua uccguaggaa acacccuaua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca ucaucaauuu cuacgacccc     1500

cuagucuucc cuuccgacga guucgacgcg uccaucagcc aagucaauga aaagaucaac     1560

cagagccugg cauucauccg caaauccgac gaacuccucc acaacgucaa cgcgggaaaa     1620

uccacgacaa acaucaugau caccaccauc aucaucguca ucauagucau ucuccuuucu     1680

cucaucgccg ugggacuacu ucucuacugc aaagcccgau aaggacuagu aauaaggaaa     1740

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua     1800

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1980

gaauu                                                                 1985


<210>  8238
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8238
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8239
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8239
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8240
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8240
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8241
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8241
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8242
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8242
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8243
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8243
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagau gaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8244
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8244
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau ugaaagccaa cgcaaucaca acaauacuaa ccgccguaac auuuugcuuc      240

gcgucaggcc aaaauauaac agaagaauuu uaccaaucaa caugcuccgc cguaucaaaa      300

ggauaccuag gugcauuacg aaccgguugg uacacaucag uaaucacaau agaacuuucc      360

aacauuaaag aaauaaaaug caauggcaca gacgcaaaag ucaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc cgucacagac uuacaacuau uaaugcaaag cacaccagca      480

acaggauccg gaucagcaau agcaucagga guagccgucu guaaaguacu acaccuagaa      540

ggcgaaguua auaaaauuaa aucagcuuua uuaucaacca acaaagcagu aguaucacua      600

uccggaugcg gagucuccgu ccuaacauuc aaaguacuag accucaagaa uuacauagau      660

aaacaacuac uaccaauacu caacaaacaa ucauguucaa uaccaaacau cgaaaccguc      720

auagaauuuc aacaaaaaaa uaauagacuc uuagaaauaa cacgagaauu uagcguaaac      780

gcaggaguca caaccccugu cucaacauac augcuaacca auuccgaauu auuaucacuc      840

auaaaugaca ugccaauaac uaaugaccaa aaaaaacuua ugucaaacaa cguacaaaua      900

guaagacaac aaucauauuc aauaaugugc auaaucaaag aagaaguuuu agcauaugua      960

guacaacuac cacuauaugg cgucauagac acaccaugcu ggaaauuaca cacaucaccu     1020

cuaugcacaa caaacacaaa agaaggaagc aacauuugcc uaaccagaac cgauagagga     1080

ugguacugcg auaacgcagg cucaguauca uucuucccuc aagccgaaac uugcaaaguc     1140

caaucaaaua gagucuucug cgauacaaug aacuccuuaa cuuuaccauc agaaguaaau     1200

cuaugcaacg uagauaucuu uaauccaaaa uacgauugca aaaucaugac aucaaaaaca     1260

gauguaucau cuaguguaau uaccucccua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucuaacaa augucgugga auaauaaaaa cauucucaaa cggaugcgau     1380

uauguaucaa auaaaggugu cgacaccgua ucaguaggca auacacuaua cuauguaaau     1440

aaacaagaag gacaaucacu cuacgucaaa ggugaaccaa uaauaaacuu cuacgaccca     1500

cuuguauucc caagcgacga auuugacgca ucaauaagcc aaguaaacga aaaaauaaac     1560

caaucacuag cauucaucag aaaaucagac gaacuacucc acaauguaaa ugcaggaaaa     1620

ucaacaacca auaucaugau aacaaccaua auaauaguca uaauaguaau acuauuaucc     1680

cucauagccg uuggacuacu ccuauauugu aaagcacgau aaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8245
<211>  2001
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8245
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccaucacc accauacuca ccgcaguaac cuucugcuuc      240

gcauccggcc aaaacaucac agaagaguuc uaccagagua ccugcuccgc cgucuccaaa      300

ggcuaccuug gcgcccuccg uaccgggugg uacacauccg ucaucacaau cgaacucucc      360

aacaucaaag aaauaaagug caacggcaca gacgccaaag uaaaacugau aaagcaagaa      420

cucgacaaau acaaaaacgc cguaaccgac cuccagcuac uaaugcaauc cacucccgcc      480

accggcagcg gauccgccau cgccuccgga guagccgucu guaaagucuu acaccucgaa      540

ggcgaaguga acaaaaucaa auccgcccua cucucaacca acaaagccgu aguaucacuc      600

uccgggugcg gcguuucagu gcuaacguuc aaaguccuug accucaaaaa cuacaucgac      660

aaacaacucc uccccauccu aaauaaacaa uccugcucca uacccaacau cgagacuguc      720

aucgaguucc agcagaaaaa caaccgacuc cucgaaauca cacgcgaguu cucugucaac      780

gccggcguca caacccccgu cuccacauac augcucacca acagcgaacu ccucucccua      840

aucaaugaca ugcccaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      900

guccgccaac aauccuacag caucaugugc aucaucaaag aagaaguucu cgcauacgua      960

guacaacucc cccucuacgg agugaucgac acccccugcu ggaaacuaca caccagcccg     1020

cuuugcacca caaacaccaa ggaaggcucc aacaucugcc ucacucgaac cgaccgcggc     1080

ugguacugcg acaacgcagg cuccgucagu uucuuucccc aagcagaaac augcaaaguc     1140

caauccaacc gaguauucug cgacaccaug aacucccuca cccuaccauc cgaaguuaac     1200

cuaugcaacg uggacaucuu caaccccaag uacgacugca aaauuaugac cuccaaaacc     1260

gacguauccu ccagcgucau caccagccuc ggagcaauag ucuccugcua cggcaagacc     1320

aagugcaccg cuuccaacaa gugucgcgga aucaucaaaa ccuucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacaccgua uccguaggaa acacccuaua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca ucaucaauuu cuacgacccc     1500

cuagucuucc cuuccgacga guucgacgcg uccaucagcc aagucaauga aaagaucaac     1560

cagagccugg cauucauccg caaauccgac gaacuccucc acaacgucaa cgcgggaaaa     1620

uccacgacaa acaucaugau caccaccauc aucaucguca ucauagucau ucuccuuucu     1680

cucaucgccg ugggacuacu ucucuacugc aaagcccgau aaggacuagu acuggcugca     1740

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca     1800

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa     1860

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1920

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1980

cuuuucagag ccaccagaau u                                               2001


<210>  8246
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8246
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg gaccggcugg uacaccuccg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacgggacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcaguc caccccggca      480

accggcuccg gcuccgccau cgcgagcggc gucgccgugu gcaaggugcu gcaccucgag      540

ggggagguca acaagaucaa gagcgcccug cuguccacca acaaggccgu ggugagccuc      600

uccggcugcg gcgucagcgu gcugaccuuc aaggugcugg accucaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcucca uccccaacau cgagacggug      720

aucgaguucc agcagaagaa caaccggcuc cuggagauca cccgcgaguu cagcgugaac      780

gccgggguca ccacccccgu guccacguac augcugacca acagcgagcu ccugucccug      840

aucaacgaca ugccgaucac caacgaccag aagaagcuca ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggcguacgug      960

guccagcugc cccucuacgg cgugaucgac acccccugcu ggaagcugca cacgagcccc     1020

cugugcacca ccaacaccaa ggaggggucc aacaucugcc ucacgcgcac cgaccggggc     1080

ugguacugcg acaacgccgg cagcgucucc uucuucccgc aggccgagac cugcaaggug     1140

cagagcaacc gcguguucug cgacaccaug aacucccuga cgcugcccag cgagguaaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgugagcu ccagcgugau caccucccug ggggccaucg ucagcugcua cggcaagacg     1320

aagugcaccg ccagcaacaa gugccggggg aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug uccgucggga acacccugua cuacgugaac     1440

aagcaggagg gccagagccu cuacgugaag ggggagccca ucaucaacuu cuacgacccg     1500

cuggucuucc ccuccgacga guucgacgcg agcaucuccc aggugaacga gaagaucaac     1560

cagagccugg ccuucauccg caaguccgac gagcugcucc acaacgugaa cgccggcaag     1620

agcacgacca acaucaugau caccaccauc aucaucguca ucaucgugau ccugcugucc     1680

cucaucgccg uggggcugcu gcucuacugc aaggcccggu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8247
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8247
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgccaucacc accauccuga cggcggugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagucca cgugcagcgc cgucuccaag      300

ggguaccucg gcgcccugcg caccgggugg uacaccagcg ugaucaccau cgagcugucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcucau caagcaggag      420

cuggacaagu acaagaacgc ggucacggac cugcagcucc ugaugcagag cacccccgcc      480

accggguccg gcagcgccau cgccuccggc guggcggugu gcaagguccu gcaccucgag      540

ggggagguga acaagaucaa gagcgcccug cuguccacca acaaggccgu ggucagccuc      600

uccggcugcg gggugagcgu gcugacguuc aagguccugg accucaagaa cuacaucgac      660

aagcagcugc ugccgauccu caacaagcag uccugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caaccggcug cuggagauca cccgcgaguu cuccgugaac      780

gccggcguca ccacgcccgu gagcaccuac augcucacca acuccgagcu gcugagccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

guccggcagc aguccuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

guccagcucc cgcuguacgg ggugaucgac acgcccugcu ggaagcugca caccagcccc     1020

cucugcacca ccaacacgaa ggagggcucc aacaucugcc ugacccgcac cgaccggggc     1080

ugguacugcg acaacgcggg guccgugagc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcguguucug cgacacgaug aacagccuga cccucccguc cgaggucaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugucca gcuccgucau cacgagccug ggcgccaucg uguccugcua cgggaagacc     1320

aagugcaccg ccagcaacaa gugccggggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgugagca acaagggggu cgacacggug uccgugggca acacccucua cuacgucaac     1440

aagcaggagg ggcagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc cgagcgacga guucgacgcc uccaucagcc aggucaacga gaagaucaac     1560

cagucccucg cguucauccg caagagcgac gagcugcugc acaacgugaa cgccgggaag     1620

uccaccacca acaucaugau caccacgauc aucaucguga ucaucgucau ccuccugagc     1680

cugaucgccg ugggccuccu gcuguacugc aaggcccggu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8248
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8248
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cuccucaucc ucaaggccaa cgccaucacc accauccuca ccgccgucac cuucugcuuc      240

gccuccggcc agaacaucac cgaggaguuc uaccagucca ccugcuccgc cgucuccaag      300

ggcuaccucg gcgcccuccg caccggcugg uacaccuccg ucaucaccau cgagcucucc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ucaagcucau caagcaggag      420

cucgacaagu acaagaacgc cgucaccgac cuccagcucc ucaugcaguc cacccccgcc      480

accggcuccg gcuccgccau cgccuccggc gucgccgucu gcaagguccu ccaccucgag      540

ggcgagguca acaagaucaa guccgcccuc cucuccacca acaaggccgu cgucucccuc      600

uccggcugcg gcgucuccgu ccucaccuuc aagguccucg accucaagaa cuacaucgac      660

aagcagcucc uccccauccu caacaagcag uccugcucca uccccaacau cgagaccguc      720

aucgaguucc agcagaagaa caaccgccuc cucgagauca cccgcgaguu cuccgucaac      780

gccggcguca ccacccccgu cuccaccuac augcucacca acuccgagcu ccucucccuc      840

aucaacgaca ugcccaucac caacgaccag aagaagcuca uguccaacaa cguccagauc      900

guccgccagc aguccuacuc caucaugugc aucaucaagg aggagguccu cgccuacguc      960

guccagcucc cccucuacgg cgucaucgac acccccugcu ggaagcucca caccuccccc     1020

cucugcacca ccaacaccaa ggagggcucc aacaucugcc ucacccgcac cgaccgcggc     1080

ugguacugcg acaacgccgg cuccgucucc uucuuccccc aggccgagac cugcaagguc     1140

caguccaacc gcgucuucug cgacaccaug aacucccuca cccuccccuc cgaggucaac     1200

cucugcaacg ucgacaucuu caaccccaag uacgacugca agaucaugac cuccaagacc     1260

gacgucuccu ccuccgucau caccucccuc ggcgccaucg ucuccugcua cggcaagacc     1320

aagugcaccg ccuccaacaa gugccgcggc aucaucaaga ccuucuccaa cggcugcgac     1380

uacgucucca acaagggcgu cgacaccguc uccgucggca acacccucua cuacgucaac     1440

aagcaggagg gccagucccu cuacgucaag ggcgagccca ucaucaacuu cuacgacccc     1500

cucgucuucc ccuccgacga guucgacgcc uccaucuccc aggucaacga gaagaucaac     1560

cagucccucg ccuucauccg caaguccgac gagcuccucc acaacgucaa cgccggcaag     1620

uccaccacca acaucaugau caccaccauc aucaucguca ucaucgucau ccuccucucc     1680

cucaucgccg ucggccuccu ccucuacugc aaggcccgcu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8249
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8249
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc uuaaggccaa cgcuauuacc acaauacuga cugcagugac guucugcuuu      240

gccagcggcc agaauaucac cgaagaguuc uaccaaucca cauguucugc ggucucaaaa      300

ggguauuugg gagcuuuaag aacugguugg uacaccagug uuauuacaau cgaacugagc      360

aacauuaagg agaucaaaug caauggcacc gacgccaagg ugaaacuaau aaagcaggaa      420

cucgauaagu auaaaaacgc aguaacugac cugcagcuuc ugaugcaguc cacacccgcc      480

accgggucug gaucggcuau cgcaucaggc guggccgucu guaagguguu gcaccucgag      540

ggugagguua auaaaauuaa gagcgcucug cugaguacga acaaagccgu ggucucccuc      600

ucugggugcg gagugagcgu auuaacuuuu aagguucugg aucuuaagaa uuacaucgac      660

aaacaauugc ugccuauucu aaacaagcag uccuguucaa ucccaaauau agaaaccgug      720

auugaguucc agcagaaaaa caauaggcuc cuggaaauca cacgggaguu uagugucaac      780

gcgggcguga cuaccccggu gagcacauau augcuuacca auucugagcu guugucccuc      840

auuaacgaua ugcccaucac gaaugaccaa aagaaacuga ugucaaacaa cguccagauc      900

guucgccagc agagcuacag uauuaugugc auaaucaagg aagagguguu agcauaugua      960

gugcaacugc cucucuacgg cgucauugau acuccauguu ggaaacuuca uacaucuccc     1020

cugugcacca cuaauacaaa ggaagggucc aacaucuguu ugacccgaac ggaccgugga     1080

ugguacugcg auaaugccgg uagcgugucg uucuuuccuc aggcugagac cuguaagguu     1140

cagucuaaca gaguguucug cgacacaaug aacucccuaa cucugccauc agaagucaau     1200

cucugcaaug uggauauauu uaaccccaaa uaugacugua agauuaugac caguaaaaca     1260

gauguaagcu ccucuguuau cacuagccug ggcgccaucg ugucaugcua cgggaagacc     1320

aaauguacag caaguaauaa gugcagggga auuaucaaga ccuucuccaa cggcugugac     1380

uaugucagca auaaaggugu ggacacuguc ucugugggga acacgcuuua cuauguuaau     1440

aagcaagagg gacagucacu guacgugaaa ggcgagccua uuauaaacuu uuaugaucca     1500

uugguauucc cgagugacga auuugaugcu agcaucuccc aggucaauga gaagauuaac     1560

cagucucucg ccuucauccg gaaaucggac gaacuguuac acaacgugaa ugcgggcaag     1620

agcacaacca acaucaugau uacuaccaua aucauuguua ucauugugau ccugcuaucc     1680

cucauagccg ucgggcugcu uuuguacugc aaggcacgcu gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8250
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8250
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcugaucc ugaaggccaa cgccaucacc accauccuga ccgccgugac cuucugcuuc      240

gccagcggcc agaacaucac cgaggaguuc uaccagagca ccugcagcgc cgugagcaag      300

ggcuaccugg gcgcccugag aaccggcugg uacaccagcg ugaucaccau cgagcugagc      360

aacaucaagg agaucaagug caacggcacc gacgccaagg ugaagcugau caagcaggag      420

cuggacaagu acaagaacgc cgugaccgac cugcagcugc ugaugcagag cacccccgcc      480

accggcagcg gcagcgccau cgccagcggc guggccgugu gcaaggugcu gcaccuggag      540

ggcgagguga acaagaucaa gagcgcccug cugagcacca acaaggccgu ggugagccug      600

agcggcugcg gcgugagcgu gcugaccuuc aaggugcugg accugaagaa cuacaucgac      660

aagcagcugc ugcccauccu gaacaagcag agcugcagca uccccaacau cgagaccgug      720

aucgaguucc agcagaagaa caacagacug cuggagauca ccagagaguu cagcgugaac      780

gccggcguga ccacccccgu gagcaccuac augcugacca acagcgagcu gcugagccug      840

aucaacgaca ugcccaucac caacgaccag aagaagcuga ugagcaacaa cgugcagauc      900

gugagacagc agagcuacag caucaugugc aucaucaagg aggaggugcu ggccuacgug      960

gugcagcugc cccuguacgg cgugaucgac acccccugcu ggaagcugca caccagcccc     1020

cugugcacca ccaacaccaa ggagggcagc aacaucugcc ugaccagaac cgacagaggc     1080

ugguacugcg acaacgccgg cagcgugagc uucuuccccc aggccgagac cugcaaggug     1140

cagagcaaca gaguguucug cgacaccaug aacagccuga cccugcccag cgaggugaac     1200

cugugcaacg uggacaucuu caaccccaag uacgacugca agaucaugac cagcaagacc     1260

gacgugagca gcagcgugau caccagccug ggcgccaucg ugagcugcua cggcaagacc     1320

aagugcaccg ccagcaacaa gugcagaggc aucaucaaga ccuucagcaa cggcugcgac     1380

uacgugagca acaagggcgu ggacaccgug agcgugggca acacccugua cuacgugaac     1440

aagcaggagg gccagagccu guacgugaag ggcgagccca ucaucaacuu cuacgacccc     1500

cugguguucc ccagcgacga guucgacgcc agcaucagcc aggugaacga gaagaucaac     1560

cagagccugg ccuucaucag aaagagcgac gagcugcugc acaacgugaa cgccggcaag     1620

agcaccacca acaucaugau caccaccauc aucaucguga ucaucgugau ccugcugagc     1680

cugaucgccg ugggccugcu gcuguacugc aaggccagau gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8251
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8251
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

cugcucaucc ugaaggccaa cgcuauuacc acaauccuua cggccgugac cuucugcuuu      240

gcgagcggcc agaauauuac agaagaguuc uaccaaucca ccuguucugc ugucagcaaa      300

ggguaucugg gagcccucag aacaggcugg uacaccuccg uuaucacaau ugaacugucu      360

aacaucaagg agaucaaaug caaugggacc gacgccaagg ugaaacuuau uaagcaggaa      420

cuggauaagu auaaaaacgc ugugacggac cuccagcugc ugaugcagag cacccccgcc      480

acaggauccg gcucugcuau cgccagcggg gucgcggugu guaagguucu ccaccuggag      540

ggagagguga auaaaauuaa guccgcccuu cugagcacca acaaagcugu cgugucucuc      600

uccggcugcg gcguuagcgu gcugacauuu aagguccuug aucugaagaa uuacaucgac      660

aaacaacucc ugccuauucu gaacaagcag ucuuguucca ucccgaauau ugaaaccgug      720

aucgaguucc agcagaaaaa caaucggcuc cuggaaauca cgcgcgaguu uagcgugaac      780

gccgggguca caacccccgu uucuacauau augcuuacca auuccgagcu gcucagccug      840

auuaacgaua ugccuaucac caaugaccaa aagaaacuua uguccaacaa cgugcagauu      900

gugagacagc agucuuacag caucaugugc auuaucaagg aagagguccu ggcuuaugug      960

guucaacucc cccuguacgg agugaucgau acaccuuguu ggaaacugca uacgagcccc     1020

cucugcacca caaauaccaa ggaaggcagc aacauuuguc ugacacggac cgaccgcggg     1080

ugguacugcg auaaugccgg aucugucucc uucuuuccuc aggcggagac guguaaggug     1140

cagagcaaca gaguuuucug cgacacaaug aacucucuua cccugccgag cgaagugaau     1200

cucugcaaug ucgauaucuu uaaccccaaa uaugacugua agauuaugac cuccaaaaca     1260

gaugugucua gcuccgucau caccagccug ggcgccauug ugucuugcua cgggaagaca     1320

aaauguacgg cuuccaauaa gugccgggga aucaucaaga ccuucagcaa cggcugugac     1380

uauguuucua auaaaggcgu ggacacaguc uccgugggga acacccuuua cuauguuaau     1440

aagcaagagg gacagagccu guacgugaaa ggcgagccua uuaucaacuu uuaugauccc     1500

cucgucuucc cuuccgacga auuugaugcc ucuauuagcc aggugaauga gaagaucaac     1560

cagucccugg cuuucauucg caaaucugac gaacugcucc acaacgugaa ugccgggaag     1620

uccacaacca acaucaugau uacgaccauc aucauuguua ucauugucau ccugcuuucc     1680

cugauugccg ugggacuccu gcuguacugc aaggcuagau gaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8252
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8252
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuacucauau ugaaagccaa cgcaaucaca acaauacuaa ccgccguaac auuuugcuuc      240

gcgucaggcc aaaauauaac agaagaauuu uaccaaucaa caugcuccgc cguaucaaaa      300

ggauaccuag gugcauuacg aaccgguugg uacacaucag uaaucacaau agaacuuucc      360

aacauuaaag aaauaaaaug caauggcaca gacgcaaaag ucaaacuaau aaaacaagaa      420

cuagacaaau auaaaaacgc cgucacagac uuacaacuau uaaugcaaag cacaccagca      480

acaggauccg gaucagcaau agcaucagga guagccgucu guaaaguacu acaccuagaa      540

ggcgaaguua auaaaauuaa aucagcuuua uuaucaacca acaaagcagu aguaucacua      600

uccggaugcg gagucuccgu ccuaacauuc aaaguacuag accucaagaa uuacauagau      660

aaacaacuac uaccaauacu caacaaacaa ucauguucaa uaccaaacau cgaaaccguc      720

auagaauuuc aacaaaaaaa uaauagacuc uuagaaauaa cacgagaauu uagcguaaac      780

gcaggaguca caaccccugu cucaacauac augcuaacca auuccgaauu auuaucacuc      840

auaaaugaca ugccaauaac uaaugaccaa aaaaaacuua ugucaaacaa cguacaaaua      900

guaagacaac aaucauauuc aauaaugugc auaaucaaag aagaaguuuu agcauaugua      960

guacaacuac cacuauaugg cgucauagac acaccaugcu ggaaauuaca cacaucaccu     1020

cuaugcacaa caaacacaaa agaaggaagc aacauuugcc uaaccagaac cgauagagga     1080

ugguacugcg auaacgcagg cucaguauca uucuucccuc aagccgaaac uugcaaaguc     1140

caaucaaaua gagucuucug cgauacaaug aacuccuuaa cuuuaccauc agaaguaaau     1200

cuaugcaacg uagauaucuu uaauccaaaa uacgauugca aaaucaugac aucaaaaaca     1260

gauguaucau cuaguguaau uaccucccua ggagcaauag uaagcugcua cggaaaaaca     1320

aaaugcaccg ccucuaacaa augucgugga auaauaaaaa cauucucaaa cggaugcgau     1380

uauguaucaa auaaaggugu cgacaccgua ucaguaggca auacacuaua cuauguaaau     1440

aaacaagaag gacaaucacu cuacgucaaa ggugaaccaa uaauaaacuu cuacgaccca     1500

cuuguauucc caagcgacga auuugacgca ucaauaagcc aaguaaacga aaaaauaaac     1560

caaucacuag cauucaucag aaaaucagac gaacuacucc acaauguaaa ugcaggaaaa     1620

ucaacaacca auaucaugau aacaaccaua auaauaguca uaauaguaau acuauuaucc     1680

cucauagccg uuggacuacu ccuauauugu aaagcacgau aaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8253
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8253
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

cuccucaucc ucaaagccaa cgccaucacc accauacuca ccgcaguaac cuucugcuuc      240

gcauccggcc aaaacaucac agaagaguuc uaccagagua ccugcuccgc cgucuccaaa      300

ggcuaccuug gcgcccuccg uaccgggugg uacacauccg ucaucacaau cgaacucucc      360

aacaucaaag aaauaaagug caacggcaca gacgccaaag uaaaacugau aaagcaagaa      420

cucgacaaau acaaaaacgc cguaaccgac cuccagcuac uaaugcaauc cacucccgcc      480

accggcagcg gauccgccau cgccuccgga guagccgucu guaaagucuu acaccucgaa      540

ggcgaaguga acaaaaucaa auccgcccua cucucaacca acaaagccgu aguaucacuc      600

uccgggugcg gcguuucagu gcuaacguuc aaaguccuug accucaaaaa cuacaucgac      660

aaacaacucc uccccauccu aaauaaacaa uccugcucca uacccaacau cgagacuguc      720

aucgaguucc agcagaaaaa caaccgacuc cucgaaauca cacgcgaguu cucugucaac      780

gccggcguca caacccccgu cuccacauac augcucacca acagcgaacu ccucucccua      840

aucaaugaca ugcccaucac caacgaccaa aagaaacuca ugucaaacaa cguccaaauc      900

guccgccaac aauccuacag caucaugugc aucaucaaag aagaaguucu cgcauacgua      960

guacaacucc cccucuacgg agugaucgac acccccugcu ggaaacuaca caccagcccg     1020

cuuugcacca caaacaccaa ggaaggcucc aacaucugcc ucacucgaac cgaccgcggc     1080

ugguacugcg acaacgcagg cuccgucagu uucuuucccc aagcagaaac augcaaaguc     1140

caauccaacc gaguauucug cgacaccaug aacucccuca cccuaccauc cgaaguuaac     1200

cuaugcaacg uggacaucuu caaccccaag uacgacugca aaauuaugac cuccaaaacc     1260

gacguauccu ccagcgucau caccagccuc ggagcaauag ucuccugcua cggcaagacc     1320

aagugcaccg cuuccaacaa gugucgcgga aucaucaaaa ccuucucaaa cggcugcgac     1380

uacgucucca acaaaggcgu cgacaccgua uccguaggaa acacccuaua cuacgucaac     1440

aaacaagaag gacaaucccu cuaugucaaa ggcgaaccca ucaucaauuu cuacgacccc     1500

cuagucuucc cuuccgacga guucgacgcg uccaucagcc aagucaauga aaagaucaac     1560

cagagccugg cauucauccg caaauccgac gaacuccucc acaacgucaa cgcgggaaaa     1620

uccacgacaa acaucaugau caccaccauc aucaucguca ucauagucau ucuccuuucu     1680

cucaucgccg ugggacuacu ucucuacugc aaagcccgau aaggacuagu guccaccugu     1740

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8254
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8254
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcggaccggc ugguacaccu ccgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggg accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca guccaccccg      360

gcaaccggcu ccggcuccgc caucgcgagc ggcgucgccg ugugcaaggu gcugcaccuc      420

gagggggagg ucaacaagau caagagcgcc cugcugucca ccaacaaggc cguggugagc      480

cucuccggcu gcggcgucag cgugcugacc uucaaggugc uggaccucaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugcu ccauccccaa caucgagacg      600

gugaucgagu uccagcagaa gaacaaccgg cuccuggaga ucacccgcga guucagcgug      660

aacgccgggg ucaccacccc cguguccacg uacaugcuga ccaacagcga gcuccugucc      720

cugaucaacg acaugccgau caccaacgac cagaagaagc ucaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggcguac      840

gugguccagc ugccccucua cggcgugauc gacacccccu gcuggaagcu gcacacgagc      900

ccccugugca ccaccaacac caaggagggg uccaacaucu gccucacgcg caccgaccgg      960

ggcugguacu gcgacaacgc cggcagcguc uccuucuucc cgcaggccga gaccugcaag     1020

gugcagagca accgcguguu cugcgacacc augaacuccc ugacgcugcc cagcgaggua     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacguga gcuccagcgu gaucaccucc cugggggcca ucgucagcug cuacggcaag     1200

acgaagugca ccgccagcaa caagugccgg gggaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc guguccgucg ggaacacccu guacuacgug     1320

aacaagcagg agggccagag ccucuacgug aagggggagc ccaucaucaa cuucuacgac     1380

ccgcuggucu uccccuccga cgaguucgac gcgagcaucu cccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau ccgcaagucc gacgagcugc uccacaacgu gaacgccggc     1500

aagagcacga ccaacaucau gaucaccacc aucaucaucg ucaucaucgu gauccugcug     1560

ucccucaucg ccguggggcu gcugcucuac ugcaaggccc ggugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8255
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8255
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgccauc accaccaucc ugacggcggu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccagu ccacgugcag cgccgucucc      180

aagggguacc ucggcgcccu gcgcaccggg ugguacacca gcgugaucac caucgagcug      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu caucaagcag      300

gagcuggaca aguacaagaa cgcggucacg gaccugcagc uccugaugca gagcaccccc      360

gccaccgggu ccggcagcgc caucgccucc ggcguggcgg ugugcaaggu ccugcaccuc      420

gagggggagg ugaacaagau caagagcgcc cugcugucca ccaacaaggc cguggucagc      480

cucuccggcu gcggggugag cgugcugacg uucaaggucc uggaccucaa gaacuacauc      540

gacaagcagc ugcugccgau ccucaacaag caguccugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaaccgg cugcuggaga ucacccgcga guucuccgug      660

aacgccggcg ucaccacgcc cgugagcacc uacaugcuca ccaacuccga gcugcugagc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucguccggc agcaguccua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

gugguccagc ucccgcugua cggggugauc gacacgcccu gcuggaagcu gcacaccagc      900

ccccucugca ccaccaacac gaaggagggc uccaacaucu gccugacccg caccgaccgg      960

ggcugguacu gcgacaacgc gggguccgug agcuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcguguu cugcgacacg augaacagcc ugacccuccc guccgagguc     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacgugu ccagcuccgu caucacgagc cugggcgcca ucguguccug cuacgggaag     1200

accaagugca ccgccagcaa caagugccgg ggcaucauca agaccuucuc caacggcugc     1260

gacuacguga gcaacaaggg ggucgacacg guguccgugg gcaacacccu cuacuacguc     1320

aacaagcagg aggggcagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu ucccgagcga cgaguucgac gccuccauca gccaggucaa cgagaagauc     1440

aaccaguccc ucgcguucau ccgcaagagc gacgagcugc ugcacaacgu gaacgccggg     1500

aaguccacca ccaacaucau gaucaccacg aucaucaucg ugaucaucgu cauccuccug     1560

agccugaucg ccgugggccu ccugcuguac ugcaaggccc ggugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8256
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8256
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcuccuca uccucaaggc caacgccauc accaccaucc ucaccgccgu caccuucugc      120

uucgccuccg gccagaacau caccgaggag uucuaccagu ccaccugcuc cgccgucucc      180

aagggcuacc ucggcgcccu ccgcaccggc ugguacaccu ccgucaucac caucgagcuc      240

uccaacauca aggagaucaa gugcaacggc accgacgcca aggucaagcu caucaagcag      300

gagcucgaca aguacaagaa cgccgucacc gaccuccagc uccucaugca guccaccccc      360

gccaccggcu ccggcuccgc caucgccucc ggcgucgccg ucugcaaggu ccuccaccuc      420

gagggcgagg ucaacaagau caaguccgcc cuccucucca ccaacaaggc cgucgucucc      480

cucuccggcu gcggcgucuc cguccucacc uucaaggucc ucgaccucaa gaacuacauc      540

gacaagcagc uccuccccau ccucaacaag caguccugcu ccauccccaa caucgagacc      600

gucaucgagu uccagcagaa gaacaaccgc cuccucgaga ucacccgcga guucuccguc      660

aacgccggcg ucaccacccc cgucuccacc uacaugcuca ccaacuccga gcuccucucc      720

cucaucaacg acaugcccau caccaacgac cagaagaagc ucauguccaa caacguccag      780

aucguccgcc agcaguccua cuccaucaug ugcaucauca aggaggaggu ccucgccuac      840

gucguccagc ucccccucua cggcgucauc gacacccccu gcuggaagcu ccacaccucc      900

ccccucugca ccaccaacac caaggagggc uccaacaucu gccucacccg caccgaccgc      960

ggcugguacu gcgacaacgc cggcuccguc uccuucuucc cccaggccga gaccugcaag     1020

guccagucca accgcgucuu cugcgacacc augaacuccc ucacccuccc cuccgagguc     1080

aaccucugca acgucgacau cuucaacccc aaguacgacu gcaagaucau gaccuccaag     1140

accgacgucu ccuccuccgu caucaccucc cucggcgcca ucgucuccug cuacggcaag     1200

accaagugca ccgccuccaa caagugccgc ggcaucauca agaccuucuc caacggcugc     1260

gacuacgucu ccaacaaggg cgucgacacc gucuccgucg gcaacacccu cuacuacguc     1320

aacaagcagg agggccaguc ccucuacguc aagggcgagc ccaucaucaa cuucuacgac     1380

ccccucgucu uccccuccga cgaguucgac gccuccaucu cccaggucaa cgagaagauc     1440

aaccaguccc ucgccuucau ccgcaagucc gacgagcucc uccacaacgu caacgccggc     1500

aaguccacca ccaacaucau gaucaccacc aucaucaucg ucaucaucgu cauccuccuc     1560

ucccucaucg ccgucggccu ccuccucuac ugcaaggccc gcugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8257
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8257
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccuuaaggc caacgcuauu accacaauac ugacugcagu gacguucugc      120

uuugccagcg gccagaauau caccgaagag uucuaccaau ccacauguuc ugcggucuca      180

aaaggguauu ugggagcuuu aagaacuggu ugguacacca guguuauuac aaucgaacug      240

agcaacauua aggagaucaa augcaauggc accgacgcca aggugaaacu aauaaagcag      300

gaacucgaua aguauaaaaa cgcaguaacu gaccugcagc uucugaugca guccacaccc      360

gccaccgggu cuggaucggc uaucgcauca ggcguggccg ucuguaaggu guugcaccuc      420

gagggugagg uuaauaaaau uaagagcgcu cugcugagua cgaacaaagc cguggucucc      480

cucucugggu gcggagugag cguauuaacu uuuaagguuc uggaucuuaa gaauuacauc      540

gacaaacaau ugcugccuau ucuaaacaag caguccuguu caaucccaaa uauagaaacc      600

gugauugagu uccagcagaa aaacaauagg cuccuggaaa ucacacggga guuuaguguc      660

aacgcgggcg ugacuacccc ggugagcaca uauaugcuua ccaauucuga gcuguugucc      720

cucauuaacg auaugcccau cacgaaugac caaaagaaac ugaugucaaa caacguccag      780

aucguucgcc agcagagcua caguauuaug ugcauaauca aggaagaggu guuagcauau      840

guagugcaac ugccucucua cggcgucauu gauacuccau guuggaaacu ucauacaucu      900

ccccugugca ccacuaauac aaaggaaggg uccaacaucu guuugacccg aacggaccgu      960

ggaugguacu gcgauaaugc cgguagcgug ucguucuuuc cucaggcuga gaccuguaag     1020

guucagucua acagaguguu cugcgacaca augaacuccc uaacucugcc aucagaaguc     1080

aaucucugca auguggauau auuuaacccc aaauaugacu guaagauuau gaccaguaaa     1140

acagauguaa gcuccucugu uaucacuagc cugggcgcca ucgugucaug cuacgggaag     1200

accaaaugua cagcaaguaa uaagugcagg ggaauuauca agaccuucuc caacggcugu     1260

gacuauguca gcaauaaagg uguggacacu gucucugugg ggaacacgcu uuacuauguu     1320

aauaagcaag agggacaguc acuguacgug aaaggcgagc cuauuauaaa cuuuuaugau     1380

ccauugguau ucccgaguga cgaauuugau gcuagcaucu cccaggucaa ugagaagauu     1440

aaccagucuc ucgccuucau ccggaaaucg gacgaacugu uacacaacgu gaaugcgggc     1500

aagagcacaa ccaacaucau gauuacuacc auaaucauug uuaucauugu gauccugcua     1560

ucccucauag ccgucgggcu gcuuuuguac ugcaaggcac gcugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8258
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8258
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuga uccugaaggc caacgccauc accaccaucc ugaccgccgu gaccuucugc      120

uucgccagcg gccagaacau caccgaggag uucuaccaga gcaccugcag cgccgugagc      180

aagggcuacc ugggcgcccu gagaaccggc ugguacacca gcgugaucac caucgagcug      240

agcaacauca aggagaucaa gugcaacggc accgacgcca aggugaagcu gaucaagcag      300

gagcuggaca aguacaagaa cgccgugacc gaccugcagc ugcugaugca gagcaccccc      360

gccaccggca gcggcagcgc caucgccagc ggcguggccg ugugcaaggu gcugcaccug      420

gagggcgagg ugaacaagau caagagcgcc cugcugagca ccaacaaggc cguggugagc      480

cugagcggcu gcggcgugag cgugcugacc uucaaggugc uggaccugaa gaacuacauc      540

gacaagcagc ugcugcccau ccugaacaag cagagcugca gcauccccaa caucgagacc      600

gugaucgagu uccagcagaa gaacaacaga cugcuggaga ucaccagaga guucagcgug      660

aacgccggcg ugaccacccc cgugagcacc uacaugcuga ccaacagcga gcugcugagc      720

cugaucaacg acaugcccau caccaacgac cagaagaagc ugaugagcaa caacgugcag      780

aucgugagac agcagagcua cagcaucaug ugcaucauca aggaggaggu gcuggccuac      840

guggugcagc ugccccugua cggcgugauc gacacccccu gcuggaagcu gcacaccagc      900

ccccugugca ccaccaacac caaggagggc agcaacaucu gccugaccag aaccgacaga      960

ggcugguacu gcgacaacgc cggcagcgug agcuucuucc cccaggccga gaccugcaag     1020

gugcagagca acagaguguu cugcgacacc augaacagcc ugacccugcc cagcgaggug     1080

aaccugugca acguggacau cuucaacccc aaguacgacu gcaagaucau gaccagcaag     1140

accgacguga gcagcagcgu gaucaccagc cugggcgcca ucgugagcug cuacggcaag     1200

accaagugca ccgccagcaa caagugcaga ggcaucauca agaccuucag caacggcugc     1260

gacuacguga gcaacaaggg cguggacacc gugagcgugg gcaacacccu guacuacgug     1320

aacaagcagg agggccagag ccuguacgug aagggcgagc ccaucaucaa cuucuacgac     1380

ccccuggugu uccccagcga cgaguucgac gccagcauca gccaggugaa cgagaagauc     1440

aaccagagcc uggccuucau cagaaagagc gacgagcugc ugcacaacgu gaacgccggc     1500

aagagcacca ccaacaucau gaucaccacc aucaucaucg ugaucaucgu gauccugcug     1560

agccugaucg ccgugggccu gcugcuguac ugcaaggcca gaugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8259
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8259
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagcugcuca uccugaaggc caacgcuauu accacaaucc uuacggccgu gaccuucugc      120

uuugcgagcg gccagaauau uacagaagag uucuaccaau ccaccuguuc ugcugucagc      180

aaaggguauc ugggagcccu cagaacaggc ugguacaccu ccguuaucac aauugaacug      240

ucuaacauca aggagaucaa augcaauggg accgacgcca aggugaaacu uauuaagcag      300

gaacuggaua aguauaaaaa cgcugugacg gaccuccagc ugcugaugca gagcaccccc      360

gccacaggau ccggcucugc uaucgccagc ggggucgcgg uguguaaggu ucuccaccug      420

gagggagagg ugaauaaaau uaaguccgcc cuucugagca ccaacaaagc ugucgugucu      480

cucuccggcu gcggcguuag cgugcugaca uuuaaggucc uugaucugaa gaauuacauc      540

gacaaacaac uccugccuau ucugaacaag cagucuuguu ccaucccgaa uauugaaacc      600

gugaucgagu uccagcagaa aaacaaucgg cuccuggaaa ucacgcgcga guuuagcgug      660

aacgccgggg ucacaacccc cguuucuaca uauaugcuua ccaauuccga gcugcucagc      720

cugauuaacg auaugccuau caccaaugac caaaagaaac uuauguccaa caacgugcag      780

auugugagac agcagucuua cagcaucaug ugcauuauca aggaagaggu ccuggcuuau      840

gugguucaac ucccccugua cggagugauc gauacaccuu guuggaaacu gcauacgagc      900

ccccucugca ccacaaauac caaggaaggc agcaacauuu gucugacacg gaccgaccgc      960

gggugguacu gcgauaaugc cggaucuguc uccuucuuuc cucaggcgga gacguguaag     1020

gugcagagca acagaguuuu cugcgacaca augaacucuc uuacccugcc gagcgaagug     1080

aaucucugca augucgauau cuuuaacccc aaauaugacu guaagauuau gaccuccaaa     1140

acagaugugu cuagcuccgu caucaccagc cugggcgcca uugugucuug cuacgggaag     1200

acaaaaugua cggcuuccaa uaagugccgg ggaaucauca agaccuucag caacggcugu     1260

gacuauguuu cuaauaaagg cguggacaca gucuccgugg ggaacacccu uuacuauguu     1320

aauaagcaag agggacagag ccuguacgug aaaggcgagc cuauuaucaa cuuuuaugau     1380

ccccucgucu ucccuuccga cgaauuugau gccucuauua gccaggugaa ugagaagauc     1440

aaccaguccc uggcuuucau ucgcaaaucu gacgaacugc uccacaacgu gaaugccggg     1500

aaguccacaa ccaacaucau gauuacgacc aucaucauug uuaucauugu cauccugcuu     1560

ucccugauug ccgugggacu ccugcuguac ugcaaggcua gaugaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8260
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8260
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuacuca uauugaaagc caacgcaauc acaacaauac uaaccgccgu aacauuuugc      120

uucgcgucag gccaaaauau aacagaagaa uuuuaccaau caacaugcuc cgccguauca      180

aaaggauacc uaggugcauu acgaaccggu ugguacacau caguaaucac aauagaacuu      240

uccaacauua aagaaauaaa augcaauggc acagacgcaa aagucaaacu aauaaaacaa      300

gaacuagaca aauauaaaaa cgccgucaca gacuuacaac uauuaaugca aagcacacca      360

gcaacaggau ccggaucagc aauagcauca ggaguagccg ucuguaaagu acuacaccua      420

gaaggcgaag uuaauaaaau uaaaucagcu uuauuaucaa ccaacaaagc aguaguauca      480

cuauccggau gcggagucuc cguccuaaca uucaaaguac uagaccucaa gaauuacaua      540

gauaaacaac uacuaccaau acucaacaaa caaucauguu caauaccaaa caucgaaacc      600

gucauagaau uucaacaaaa aaauaauaga cucuuagaaa uaacacgaga auuuagcgua      660

aacgcaggag ucacaacccc ugucucaaca uacaugcuaa ccaauuccga auuauuauca      720

cucauaaaug acaugccaau aacuaaugac caaaaaaaac uuaugucaaa caacguacaa      780

auaguaagac aacaaucaua uucaauaaug ugcauaauca aagaagaagu uuuagcauau      840

guaguacaac uaccacuaua uggcgucaua gacacaccau gcuggaaauu acacacauca      900

ccucuaugca caacaaacac aaaagaagga agcaacauuu gccuaaccag aaccgauaga      960

ggaugguacu gcgauaacgc aggcucagua ucauucuucc cucaagccga aacuugcaaa     1020

guccaaucaa auagagucuu cugcgauaca augaacuccu uaacuuuacc aucagaagua     1080

aaucuaugca acguagauau cuuuaaucca aaauacgauu gcaaaaucau gacaucaaaa     1140

acagauguau caucuagugu aauuaccucc cuaggagcaa uaguaagcug cuacggaaaa     1200

acaaaaugca ccgccucuaa caaaugucgu ggaauaauaa aaacauucuc aaacggaugc     1260

gauuauguau caaauaaagg ugucgacacc guaucaguag gcaauacacu auacuaugua     1320

aauaaacaag aaggacaauc acucuacguc aaaggugaac caauaauaaa cuucuacgac     1380

ccacuuguau ucccaagcga cgaauuugac gcaucaauaa gccaaguaaa cgaaaaaaua     1440

aaccaaucac uagcauucau cagaaaauca gacgaacuac uccacaaugu aaaugcagga     1500

aaaucaacaa ccaauaucau gauaacaacc auaauaauag ucauaauagu aauacuauua     1560

ucccucauag ccguuggacu acuccuauau uguaaagcac gauaaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8261
<211>  1934
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8261
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaacuccuca uccucaaagc caacgccauc accaccauac ucaccgcagu aaccuucugc      120

uucgcauccg gccaaaacau cacagaagag uucuaccaga guaccugcuc cgccgucucc      180

aaaggcuacc uuggcgcccu ccguaccggg ugguacacau ccgucaucac aaucgaacuc      240

uccaacauca aagaaauaaa gugcaacggc acagacgcca aaguaaaacu gauaaagcaa      300

gaacucgaca aauacaaaaa cgccguaacc gaccuccagc uacuaaugca auccacuccc      360

gccaccggca gcggauccgc caucgccucc ggaguagccg ucuguaaagu cuuacaccuc      420

gaaggcgaag ugaacaaaau caaauccgcc cuacucucaa ccaacaaagc cguaguauca      480

cucuccgggu gcggcguuuc agugcuaacg uucaaagucc uugaccucaa aaacuacauc      540

gacaaacaac uccuccccau ccuaaauaaa caauccugcu ccauacccaa caucgagacu      600

gucaucgagu uccagcagaa aaacaaccga cuccucgaaa ucacacgcga guucucuguc      660

aacgccggcg ucacaacccc cgucuccaca uacaugcuca ccaacagcga acuccucucc      720

cuaaucaaug acaugcccau caccaacgac caaaagaaac ucaugucaaa caacguccaa      780

aucguccgcc aacaauccua cagcaucaug ugcaucauca aagaagaagu ucucgcauac      840

guaguacaac ucccccucua cggagugauc gacacccccu gcuggaaacu acacaccagc      900

ccgcuuugca ccacaaacac caaggaaggc uccaacaucu gccucacucg aaccgaccgc      960

ggcugguacu gcgacaacgc aggcuccguc aguuucuuuc cccaagcaga aacaugcaaa     1020

guccaaucca accgaguauu cugcgacacc augaacuccc ucacccuacc auccgaaguu     1080

aaccuaugca acguggacau cuucaacccc aaguacgacu gcaaaauuau gaccuccaaa     1140

accgacguau ccuccagcgu caucaccagc cucggagcaa uagucuccug cuacggcaag     1200

accaagugca ccgcuuccaa caagugucgc ggaaucauca aaaccuucuc aaacggcugc     1260

gacuacgucu ccaacaaagg cgucgacacc guauccguag gaaacacccu auacuacguc     1320

aacaaacaag aaggacaauc ccucuauguc aaaggcgaac ccaucaucaa uuucuacgac     1380

ccccuagucu ucccuuccga cgaguucgac gcguccauca gccaagucaa ugaaaagauc     1440

aaccagagcc uggcauucau ccgcaaaucc gacgaacucc uccacaacgu caacgcggga     1500

aaauccacga caaacaucau gaucaccacc aucaucaucg ucaucauagu cauucuccuu     1560

ucucucaucg ccgugggacu acuucucuac ugcaaagccc gauaaggacu agugcaucac     1620

auuuaaaagc aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu     1680

auucaucucu uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau     1740

uucuuuaauc auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu     1800

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1920

gagccaccag aauu                                                       1934


<210>  8262
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8262
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgg accggcuggu acaccuccgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacgggaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagucc accccggcaa      360

ccggcuccgg cuccgccauc gcgagcggcg ucgccgugug caaggugcug caccucgagg      420

gggaggucaa caagaucaag agcgcccugc uguccaccaa caaggccgug gugagccucu      480

ccggcugcgg cgucagcgug cugaccuuca aggugcugga ccucaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcuccau ccccaacauc gagacgguga      600

ucgaguucca gcagaagaac aaccggcucc uggagaucac ccgcgaguuc agcgugaacg      660

ccggggucac cacccccgug uccacguaca ugcugaccaa cagcgagcuc cugucccuga      720

ucaacgacau gccgaucacc aacgaccaga agaagcucau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gcguacgugg      840

uccagcugcc ccucuacggc gugaucgaca cccccugcug gaagcugcac acgagccccc      900

ugugcaccac caacaccaag gaggggucca acaucugccu cacgcgcacc gaccggggcu      960

gguacugcga caacgccggc agcgucuccu ucuucccgca ggccgagacc ugcaaggugc     1020

agagcaaccg cguguucugc gacaccauga acucccugac gcugcccagc gagguaaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgugagcuc cagcgugauc accucccugg gggccaucgu cagcugcuac ggcaagacga     1200

agugcaccgc cagcaacaag ugccggggga ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccgugu ccgucgggaa cacccuguac uacgugaaca     1320

agcaggaggg ccagagccuc uacgugaagg gggagcccau caucaacuuc uacgacccgc     1380

uggucuuccc cuccgacgag uucgacgcga gcaucuccca ggugaacgag aagaucaacc     1440

agagccuggc cuucauccgc aaguccgacg agcugcucca caacgugaac gccggcaaga     1500

gcacgaccaa caucaugauc accaccauca ucaucgucau caucgugauc cugcuguccc     1560

ucaucgccgu ggggcugcug cucuacugca aggcccggug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8263
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8263
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gccaucacca ccauccugac ggcggugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accaguccac gugcagcgcc gucuccaagg      180

gguaccucgg cgcccugcgc accggguggu acaccagcgu gaucaccauc gagcugucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcucauc aagcaggagc      300

uggacaagua caagaacgcg gucacggacc ugcagcuccu gaugcagagc acccccgcca      360

ccggguccgg cagcgccauc gccuccggcg uggcggugug caagguccug caccucgagg      420

gggaggugaa caagaucaag agcgcccugc uguccaccaa caaggccgug gucagccucu      480

ccggcugcgg ggugagcgug cugacguuca agguccugga ccucaagaac uacaucgaca      540

agcagcugcu gccgauccuc aacaagcagu ccugcagcau ccccaacauc gagaccguga      600

ucgaguucca gcagaagaac aaccggcugc uggagaucac ccgcgaguuc uccgugaacg      660

ccggcgucac cacgcccgug agcaccuaca ugcucaccaa cuccgagcug cugagccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

uccggcagca guccuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

uccagcuccc gcuguacggg gugaucgaca cgcccugcug gaagcugcac accagccccc      900

ucugcaccac caacacgaag gagggcucca acaucugccu gacccgcacc gaccggggcu      960

gguacugcga caacgcgggg uccgugagcu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cguguucugc gacacgauga acagccugac ccucccgucc gaggucaacc     1080

ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc agcaagaccg     1140

acguguccag cuccgucauc acgagccugg gcgccaucgu guccugcuac gggaagacca     1200

agugcaccgc cagcaacaag ugccggggca ucaucaagac cuucuccaac ggcugcgacu     1260

acgugagcaa caaggggguc gacacggugu ccgugggcaa cacccucuac uacgucaaca     1320

agcaggaggg gcagagccug uacgugaagg gcgagcccau caucaacuuc uacgaccccc     1380

ugguguuccc gagcgacgag uucgacgccu ccaucagcca ggucaacgag aagaucaacc     1440

agucccucgc guucauccgc aagagcgacg agcugcugca caacgugaac gccgggaagu     1500

ccaccaccaa caucaugauc accacgauca ucaucgugau caucgucauc cuccugagcc     1560

ugaucgccgu gggccuccug cuguacugca aggcccggug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8264
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8264
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

uccucauccu caaggccaac gccaucacca ccauccucac cgccgucacc uucugcuucg      120

ccuccggcca gaacaucacc gaggaguucu accaguccac cugcuccgcc gucuccaagg      180

gcuaccucgg cgcccuccgc accggcuggu acaccuccgu caucaccauc gagcucucca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu caagcucauc aagcaggagc      300

ucgacaagua caagaacgcc gucaccgacc uccagcuccu caugcagucc acccccgcca      360

ccggcuccgg cuccgccauc gccuccggcg ucgccgucug caagguccuc caccucgagg      420

gcgaggucaa caagaucaag uccgcccucc ucuccaccaa caaggccguc gucucccucu      480

ccggcugcgg cgucuccguc cucaccuuca agguccucga ccucaagaac uacaucgaca      540

agcagcuccu ccccauccuc aacaagcagu ccugcuccau ccccaacauc gagaccguca      600

ucgaguucca gcagaagaac aaccgccucc ucgagaucac ccgcgaguuc uccgucaacg      660

ccggcgucac cacccccguc uccaccuaca ugcucaccaa cuccgagcuc cucucccuca      720

ucaacgacau gcccaucacc aacgaccaga agaagcucau guccaacaac guccagaucg      780

uccgccagca guccuacucc aucaugugca ucaucaagga ggagguccuc gccuacgucg      840

uccagcuccc ccucuacggc gucaucgaca cccccugcug gaagcuccac accucccccc      900

ucugcaccac caacaccaag gagggcucca acaucugccu cacccgcacc gaccgcggcu      960

gguacugcga caacgccggc uccgucuccu ucuuccccca ggccgagacc ugcaaggucc     1020

aguccaaccg cgucuucugc gacaccauga acucccucac ccuccccucc gaggucaacc     1080

ucugcaacgu cgacaucuuc aaccccaagu acgacugcaa gaucaugacc uccaagaccg     1140

acgucuccuc cuccgucauc accucccucg gcgccaucgu cuccugcuac ggcaagacca     1200

agugcaccgc cuccaacaag ugccgcggca ucaucaagac cuucuccaac ggcugcgacu     1260

acgucuccaa caagggcguc gacaccgucu ccgucggcaa cacccucuac uacgucaaca     1320

agcaggaggg ccagucccuc uacgucaagg gcgagcccau caucaacuuc uacgaccccc     1380

ucgucuuccc cuccgacgag uucgacgccu ccaucuccca ggucaacgag aagaucaacc     1440

agucccucgc cuucauccgc aaguccgacg agcuccucca caacgucaac gccggcaagu     1500

ccaccaccaa caucaugauc accaccauca ucaucgucau caucgucauc cuccucuccc     1560

ucaucgccgu cggccuccuc cucuacugca aggcccgcug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8265
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8265
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu uaaggccaac gcuauuacca caauacugac ugcagugacg uucugcuuug      120

ccagcggcca gaauaucacc gaagaguucu accaauccac auguucugcg gucucaaaag      180

gguauuuggg agcuuuaaga acugguuggu acaccagugu uauuacaauc gaacugagca      240

acauuaagga gaucaaaugc aauggcaccg acgccaaggu gaaacuaaua aagcaggaac      300

ucgauaagua uaaaaacgca guaacugacc ugcagcuucu gaugcagucc acacccgcca      360

ccgggucugg aucggcuauc gcaucaggcg uggccgucug uaagguguug caccucgagg      420

gugagguuaa uaaaauuaag agcgcucugc ugaguacgaa caaagccgug gucucccucu      480

cugggugcgg agugagcgua uuaacuuuua agguucugga ucuuaagaau uacaucgaca      540

aacaauugcu gccuauucua aacaagcagu ccuguucaau cccaaauaua gaaaccguga      600

uugaguucca gcagaaaaac aauaggcucc uggaaaucac acgggaguuu agugucaacg      660

cgggcgugac uaccccggug agcacauaua ugcuuaccaa uucugagcug uugucccuca      720

uuaacgauau gcccaucacg aaugaccaaa agaaacugau gucaaacaac guccagaucg      780

uucgccagca gagcuacagu auuaugugca uaaucaagga agagguguua gcauauguag      840

ugcaacugcc ucucuacggc gucauugaua cuccauguug gaaacuucau acaucucccc      900

ugugcaccac uaauacaaag gaagggucca acaucuguuu gacccgaacg gaccguggau      960

gguacugcga uaaugccggu agcgugucgu ucuuuccuca ggcugagacc uguaagguuc     1020

agucuaacag aguguucugc gacacaauga acucccuaac ucugccauca gaagucaauc     1080

ucugcaaugu ggauauauuu aaccccaaau augacuguaa gauuaugacc aguaaaacag     1140

auguaagcuc cucuguuauc acuagccugg gcgccaucgu gucaugcuac gggaagacca     1200

aauguacagc aaguaauaag ugcaggggaa uuaucaagac cuucuccaac ggcugugacu     1260

augucagcaa uaaaggugug gacacugucu cuguggggaa cacgcuuuac uauguuaaua     1320

agcaagaggg acagucacug uacgugaaag gcgagccuau uauaaacuuu uaugauccau     1380

ugguauuccc gagugacgaa uuugaugcua gcaucuccca ggucaaugag aagauuaacc     1440

agucucucgc cuucauccgg aaaucggacg aacuguuaca caacgugaau gcgggcaaga     1500

gcacaaccaa caucaugauu acuaccauaa ucauuguuau cauugugauc cugcuauccc     1560

ucauagccgu cgggcugcuu uuguacugca aggcacgcug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8266
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8266
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcugauccu gaaggccaac gccaucacca ccauccugac cgccgugacc uucugcuucg      120

ccagcggcca gaacaucacc gaggaguucu accagagcac cugcagcgcc gugagcaagg      180

gcuaccuggg cgcccugaga accggcuggu acaccagcgu gaucaccauc gagcugagca      240

acaucaagga gaucaagugc aacggcaccg acgccaaggu gaagcugauc aagcaggagc      300

uggacaagua caagaacgcc gugaccgacc ugcagcugcu gaugcagagc acccccgcca      360

ccggcagcgg cagcgccauc gccagcggcg uggccgugug caaggugcug caccuggagg      420

gcgaggugaa caagaucaag agcgcccugc ugagcaccaa caaggccgug gugagccuga      480

gcggcugcgg cgugagcgug cugaccuuca aggugcugga ccugaagaac uacaucgaca      540

agcagcugcu gcccauccug aacaagcaga gcugcagcau ccccaacauc gagaccguga      600

ucgaguucca gcagaagaac aacagacugc uggagaucac cagagaguuc agcgugaacg      660

ccggcgugac cacccccgug agcaccuaca ugcugaccaa cagcgagcug cugagccuga      720

ucaacgacau gcccaucacc aacgaccaga agaagcugau gagcaacaac gugcagaucg      780

ugagacagca gagcuacagc aucaugugca ucaucaagga ggaggugcug gccuacgugg      840

ugcagcugcc ccuguacggc gugaucgaca cccccugcug gaagcugcac accagccccc      900

ugugcaccac caacaccaag gagggcagca acaucugccu gaccagaacc gacagaggcu      960

gguacugcga caacgccggc agcgugagcu ucuuccccca ggccgagacc ugcaaggugc     1020

agagcaacag aguguucugc gacaccauga acagccugac ccugcccagc gaggugaacc     1080

ugugcaacgu ggacaucuuc aaccccaagu acgacugcaa gaucaugacc agcaagaccg     1140

acgugagcag cagcgugauc accagccugg gcgccaucgu gagcugcuac ggcaagacca     1200

agugcaccgc cagcaacaag ugcagaggca ucaucaagac cuucagcaac ggcugcgacu     1260

acgugagcaa caagggcgug gacaccguga gcgugggcaa cacccuguac uacgugaaca     1320

agcaggaggg ccagagccug uacgugaagg gcgagcccau caucaacuuc uacgaccccc     1380

ugguguuccc cagcgacgag uucgacgcca gcaucagcca ggugaacgag aagaucaacc     1440

agagccuggc cuucaucaga aagagcgacg agcugcugca caacgugaac gccggcaaga     1500

gcaccaccaa caucaugauc accaccauca ucaucgugau caucgugauc cugcugagcc     1560

ugaucgccgu gggccugcug cuguacugca aggccagaug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8267
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8267
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggagc       60

ugcucauccu gaaggccaac gcuauuacca caauccuuac ggccgugacc uucugcuuug      120

cgagcggcca gaauauuaca gaagaguucu accaauccac cuguucugcu gucagcaaag      180

gguaucuggg agcccucaga acaggcuggu acaccuccgu uaucacaauu gaacugucua      240

acaucaagga gaucaaaugc aaugggaccg acgccaaggu gaaacuuauu aagcaggaac      300

uggauaagua uaaaaacgcu gugacggacc uccagcugcu gaugcagagc acccccgcca      360

caggauccgg cucugcuauc gccagcgggg ucgcggugug uaagguucuc caccuggagg      420

gagaggugaa uaaaauuaag uccgcccuuc ugagcaccaa caaagcuguc gugucucucu      480

ccggcugcgg cguuagcgug cugacauuua agguccuuga ucugaagaau uacaucgaca      540

aacaacuccu gccuauucug aacaagcagu cuuguuccau cccgaauauu gaaaccguga      600

ucgaguucca gcagaaaaac aaucggcucc uggaaaucac gcgcgaguuu agcgugaacg      660

ccggggucac aacccccguu ucuacauaua ugcuuaccaa uuccgagcug cucagccuga      720

uuaacgauau gccuaucacc aaugaccaaa agaaacuuau guccaacaac gugcagauug      780

ugagacagca gucuuacagc aucaugugca uuaucaagga agagguccug gcuuaugugg      840

uucaacuccc ccuguacgga gugaucgaua caccuuguug gaaacugcau acgagccccc      900

ucugcaccac aaauaccaag gaaggcagca acauuugucu gacacggacc gaccgcgggu      960

gguacugcga uaaugccgga ucugucuccu ucuuuccuca ggcggagacg uguaaggugc     1020

agagcaacag aguuuucugc gacacaauga acucucuuac ccugccgagc gaagugaauc     1080

ucugcaaugu cgauaucuuu aaccccaaau augacuguaa gauuaugacc uccaaaacag     1140

augugucuag cuccgucauc accagccugg gcgccauugu gucuugcuac gggaagacaa     1200

aauguacggc uuccaauaag ugccggggaa ucaucaagac cuucagcaac ggcugugacu     1260

auguuucuaa uaaaggcgug gacacagucu ccguggggaa cacccuuuac uauguuaaua     1320

agcaagaggg acagagccug uacgugaaag gcgagccuau uaucaacuuu uaugaucccc     1380

ucgucuuccc uuccgacgaa uuugaugccu cuauuagcca ggugaaugag aagaucaacc     1440

agucccuggc uuucauucgc aaaucugacg aacugcucca caacgugaau gccgggaagu     1500

ccacaaccaa caucaugauu acgaccauca ucauuguuau cauugucauc cugcuuuccc     1560

ugauugccgu gggacuccug cuguacugca aggcuagaug aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8268
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8268
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uacucauauu gaaagccaac gcaaucacaa caauacuaac cgccguaaca uuuugcuucg      120

cgucaggcca aaauauaaca gaagaauuuu accaaucaac augcuccgcc guaucaaaag      180

gauaccuagg ugcauuacga accgguuggu acacaucagu aaucacaaua gaacuuucca      240

acauuaaaga aauaaaaugc aauggcacag acgcaaaagu caaacuaaua aaacaagaac      300

uagacaaaua uaaaaacgcc gucacagacu uacaacuauu aaugcaaagc acaccagcaa      360

caggauccgg aucagcaaua gcaucaggag uagccgucug uaaaguacua caccuagaag      420

gcgaaguuaa uaaaauuaaa ucagcuuuau uaucaaccaa caaagcagua guaucacuau      480

ccggaugcgg agucuccguc cuaacauuca aaguacuaga ccucaagaau uacauagaua      540

aacaacuacu accaauacuc aacaaacaau cauguucaau accaaacauc gaaaccguca      600

uagaauuuca acaaaaaaau aauagacucu uagaaauaac acgagaauuu agcguaaacg      660

caggagucac aaccccuguc ucaacauaca ugcuaaccaa uuccgaauua uuaucacuca      720

uaaaugacau gccaauaacu aaugaccaaa aaaaacuuau gucaaacaac guacaaauag      780

uaagacaaca aucauauuca auaaugugca uaaucaaaga agaaguuuua gcauauguag      840

uacaacuacc acuauauggc gucauagaca caccaugcug gaaauuacac acaucaccuc      900

uaugcacaac aaacacaaaa gaaggaagca acauuugccu aaccagaacc gauagaggau      960

gguacugcga uaacgcaggc ucaguaucau ucuucccuca agccgaaacu ugcaaagucc     1020

aaucaaauag agucuucugc gauacaauga acuccuuaac uuuaccauca gaaguaaauc     1080

uaugcaacgu agauaucuuu aauccaaaau acgauugcaa aaucaugaca ucaaaaacag     1140

auguaucauc uaguguaauu accucccuag gagcaauagu aagcugcuac ggaaaaacaa     1200

aaugcaccgc cucuaacaaa ugucguggaa uaauaaaaac auucucaaac ggaugcgauu     1260

auguaucaaa uaaagguguc gacaccguau caguaggcaa uacacuauac uauguaaaua     1320

aacaagaagg acaaucacuc uacgucaaag gugaaccaau aauaaacuuc uacgacccac     1380

uuguauuccc aagcgacgaa uuugacgcau caauaagcca aguaaacgaa aaaauaaacc     1440

aaucacuagc auucaucaga aaaucagacg aacuacucca caauguaaau gcaggaaaau     1500

caacaaccaa uaucaugaua acaaccauaa uaauagucau aauaguaaua cuauuauccc     1560

ucauagccgu uggacuacuc cuauauugua aagcacgaua aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8269
<211>  1930
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8269
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaac       60

uccucauccu caaagccaac gccaucacca ccauacucac cgcaguaacc uucugcuucg      120

cauccggcca aaacaucaca gaagaguucu accagaguac cugcuccgcc gucuccaaag      180

gcuaccuugg cgcccuccgu accggguggu acacauccgu caucacaauc gaacucucca      240

acaucaaaga aauaaagugc aacggcacag acgccaaagu aaaacugaua aagcaagaac      300

ucgacaaaua caaaaacgcc guaaccgacc uccagcuacu aaugcaaucc acucccgcca      360

ccggcagcgg auccgccauc gccuccggag uagccgucug uaaagucuua caccucgaag      420

gcgaagugaa caaaaucaaa uccgcccuac ucucaaccaa caaagccgua guaucacucu      480

ccgggugcgg cguuucagug cuaacguuca aaguccuuga ccucaaaaac uacaucgaca      540

aacaacuccu ccccauccua aauaaacaau ccugcuccau acccaacauc gagacuguca      600

ucgaguucca gcagaaaaac aaccgacucc ucgaaaucac acgcgaguuc ucugucaacg      660

ccggcgucac aacccccguc uccacauaca ugcucaccaa cagcgaacuc cucucccuaa      720

ucaaugacau gcccaucacc aacgaccaaa agaaacucau gucaaacaac guccaaaucg      780

uccgccaaca auccuacagc aucaugugca ucaucaaaga agaaguucuc gcauacguag      840

uacaacuccc ccucuacgga gugaucgaca cccccugcug gaaacuacac accagcccgc      900

uuugcaccac aaacaccaag gaaggcucca acaucugccu cacucgaacc gaccgcggcu      960

gguacugcga caacgcaggc uccgucaguu ucuuucccca agcagaaaca ugcaaagucc     1020

aauccaaccg aguauucugc gacaccauga acucccucac ccuaccaucc gaaguuaacc     1080

uaugcaacgu ggacaucuuc aaccccaagu acgacugcaa aauuaugacc uccaaaaccg     1140

acguauccuc cagcgucauc accagccucg gagcaauagu cuccugcuac ggcaagacca     1200

agugcaccgc uuccaacaag ugucgcggaa ucaucaaaac cuucucaaac ggcugcgacu     1260

acgucuccaa caaaggcguc gacaccguau ccguaggaaa cacccuauac uacgucaaca     1320

aacaagaagg acaaucccuc uaugucaaag gcgaacccau caucaauuuc uacgaccccc     1380

uagucuuccc uuccgacgag uucgacgcgu ccaucagcca agucaaugaa aagaucaacc     1440

agagccuggc auucauccgc aaauccgacg aacuccucca caacgucaac gcgggaaaau     1500

ccacgacaaa caucaugauc accaccauca ucaucgucau cauagucauu cuccuuucuc     1560

ucaucgccgu gggacuacuu cucuacugca aagcccgaua aggacuagug caucacauuu     1620

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1680

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1740

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1800

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1920

caccagaauu                                                            1930


<210>  8270
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8270
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc ggaccggcug guacaccucc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacgggac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcagu ccaccccggc aaccggcucc ggcuccgcca ucgcgagcgg cgucgccgug      360

ugcaaggugc ugcaccucga gggggagguc aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggugagccu cuccggcugc ggcgucagcg ugcugaccuu caaggugcug      480

gaccucaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcucc      540

auccccaaca ucgagacggu gaucgaguuc cagcagaaga acaaccggcu ccuggagauc      600

acccgcgagu ucagcgugaa cgccgggguc accacccccg uguccacgua caugcugacc      660

aacagcgagc uccugucccu gaucaacgac augccgauca ccaacgacca gaagaagcuc      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggcguacgu gguccagcug ccccucuacg gcgugaucga cacccccugc      840

uggaagcugc acacgagccc ccugugcacc accaacacca aggagggguc caacaucugc      900

cucacgcgca ccgaccgggg cugguacugc gacaacgccg gcagcgucuc cuucuucccg      960

caggccgaga ccugcaaggu gcagagcaac cgcguguucu gcgacaccau gaacucccug     1020

acgcugccca gcgagguaaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgugagc uccagcguga ucaccucccu gggggccauc     1140

gucagcugcu acggcaagac gaagugcacc gccagcaaca agugccgggg gaucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaagggcg uggacaccgu guccgucggg     1260

aacacccugu acuacgugaa caagcaggag ggccagagcc ucuacgugaa gggggagccc     1320

aucaucaacu ucuacgaccc gcuggucuuc cccuccgacg aguucgacgc gagcaucucc     1380

caggugaacg agaagaucaa ccagagccug gccuucaucc gcaaguccga cgagcugcuc     1440

cacaacguga acgccggcaa gagcacgacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguga uccugcuguc ccucaucgcc guggggcugc ugcucuacug caaggcccgg     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8271
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt1)

<400>  8271
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgccaucac caccauccug       60

acggcgguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagucc      120

acgugcagcg ccgucuccaa gggguaccuc ggcgcccugc gcaccgggug guacaccagc      180

gugaucacca ucgagcuguc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuca ucaagcagga gcuggacaag uacaagaacg cggucacgga ccugcagcuc      300

cugaugcaga gcacccccgc caccgggucc ggcagcgcca ucgccuccgg cguggcggug      360

ugcaaggucc ugcaccucga gggggaggug aacaagauca agagcgcccu gcuguccacc      420

aacaaggccg uggucagccu cuccggcugc ggggugagcg ugcugacguu caagguccug      480

gaccucaaga acuacaucga caagcagcug cugccgaucc ucaacaagca guccugcagc      540

auccccaaca ucgagaccgu gaucgaguuc cagcagaaga acaaccggcu gcuggagauc      600

acccgcgagu ucuccgugaa cgccggcguc accacgcccg ugagcaccua caugcucacc      660

aacuccgagc ugcugagccu caucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cguccggcag caguccuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu gguccagcuc ccgcuguacg gggugaucga cacgcccugc      840

uggaagcugc acaccagccc ccucugcacc accaacacga aggagggcuc caacaucugc      900

cugacccgca ccgaccgggg cugguacugc gacaacgcgg gguccgugag cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcguguucu gcgacacgau gaacagccug     1020

acccucccgu ccgaggucaa ccugugcaac guggacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugucc agcuccguca ucacgagccu gggcgccauc     1140

guguccugcu acgggaagac caagugcacc gccagcaaca agugccgggg caucaucaag     1200

accuucucca acggcugcga cuacgugagc aacaaggggg ucgacacggu guccgugggc     1260

aacacccucu acuacgucaa caagcaggag gggcagagcc uguacgugaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccugguguuc ccgagcgacg aguucgacgc cuccaucagc     1380

caggucaacg agaagaucaa ccagucccuc gcguucaucc gcaagagcga cgagcugcug     1440

cacaacguga acgccgggaa guccaccacc aacaucauga ucaccacgau caucaucgug     1500

aucaucguca uccuccugag ccugaucgcc gugggccucc ugcuguacug caaggcccgg     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8272
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt2)

<400>  8272
gggagaaagc uuaccaugga gcuccucauc cucaaggcca acgccaucac caccauccuc       60

accgccguca ccuucugcuu cgccuccggc cagaacauca ccgaggaguu cuaccagucc      120

accugcuccg ccgucuccaa gggcuaccuc ggcgcccucc gcaccggcug guacaccucc      180

gucaucacca ucgagcucuc caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gucaagcuca ucaagcagga gcucgacaag uacaagaacg ccgucaccga ccuccagcuc      300

cucaugcagu ccacccccgc caccggcucc ggcuccgcca ucgccuccgg cgucgccguc      360

ugcaaggucc uccaccucga gggcgagguc aacaagauca aguccgcccu ccucuccacc      420

aacaaggccg ucgucucccu cuccggcugc ggcgucuccg uccucaccuu caagguccuc      480

gaccucaaga acuacaucga caagcagcuc cuccccaucc ucaacaagca guccugcucc      540

auccccaaca ucgagaccgu caucgaguuc cagcagaaga acaaccgccu ccucgagauc      600

acccgcgagu ucuccgucaa cgccggcguc accacccccg ucuccaccua caugcucacc      660

aacuccgagc uccucucccu caucaacgac augcccauca ccaacgacca gaagaagcuc      720

auguccaaca acguccagau cguccgccag caguccuacu ccaucaugug caucaucaag      780

gaggaggucc ucgccuacgu cguccagcuc ccccucuacg gcgucaucga cacccccugc      840

uggaagcucc acaccucccc ccucugcacc accaacacca aggagggcuc caacaucugc      900

cucacccgca ccgaccgcgg cugguacugc gacaacgccg gcuccgucuc cuucuucccc      960

caggccgaga ccugcaaggu ccaguccaac cgcgucuucu gcgacaccau gaacucccuc     1020

acccuccccu ccgaggucaa ccucugcaac gucgacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccuccaagac cgacgucucc uccuccguca ucaccucccu cggcgccauc     1140

gucuccugcu acggcaagac caagugcacc gccuccaaca agugccgcgg caucaucaag     1200

accuucucca acggcugcga cuacgucucc aacaagggcg ucgacaccgu cuccgucggc     1260

aacacccucu acuacgucaa caagcaggag ggccaguccc ucuacgucaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccucgucuuc cccuccgacg aguucgacgc cuccaucucc     1380

caggucaacg agaagaucaa ccagucccuc gccuucaucc gcaaguccga cgagcuccuc     1440

cacaacguca acgccggcaa guccaccacc aacaucauga ucaccaccau caucaucguc     1500

aucaucguca uccuccucuc ccucaucgcc gucggccucc uccucuacug caaggcccgc     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8273
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt3)

<400>  8273
gggagaaagc uuaccaugga gcugcucauc cuuaaggcca acgcuauuac cacaauacug       60

acugcaguga cguucugcuu ugccagcggc cagaauauca ccgaagaguu cuaccaaucc      120

acauguucug cggucucaaa aggguauuug ggagcuuuaa gaacugguug guacaccagu      180

guuauuacaa ucgaacugag caacauuaag gagaucaaau gcaauggcac cgacgccaag      240

gugaaacuaa uaaagcagga acucgauaag uauaaaaacg caguaacuga ccugcagcuu      300

cugaugcagu ccacacccgc caccgggucu ggaucggcua ucgcaucagg cguggccguc      360

uguaaggugu ugcaccucga gggugagguu aauaaaauua agagcgcucu gcugaguacg      420

aacaaagccg uggucucccu cucugggugc ggagugagcg uauuaacuuu uaagguucug      480

gaucuuaaga auuacaucga caaacaauug cugccuauuc uaaacaagca guccuguuca      540

aucccaaaua uagaaaccgu gauugaguuc cagcagaaaa acaauaggcu ccuggaaauc      600

acacgggagu uuagugucaa cgcgggcgug acuaccccgg ugagcacaua uaugcuuacc      660

aauucugagc uguugucccu cauuaacgau augcccauca cgaaugacca aaagaaacug      720

augucaaaca acguccagau cguucgccag cagagcuaca guauuaugug cauaaucaag      780

gaagaggugu uagcauaugu agugcaacug ccucucuacg gcgucauuga uacuccaugu      840

uggaaacuuc auacaucucc ccugugcacc acuaauacaa aggaaggguc caacaucugu      900

uugacccgaa cggaccgugg augguacugc gauaaugccg guagcguguc guucuuuccu      960

caggcugaga ccuguaaggu ucagucuaac agaguguucu gcgacacaau gaacucccua     1020

acucugccau cagaagucaa ucucugcaau guggauauau uuaaccccaa auaugacugu     1080

aagauuauga ccaguaaaac agauguaagc uccucuguua ucacuagccu gggcgccauc     1140

gugucaugcu acgggaagac caaauguaca gcaaguaaua agugcagggg aauuaucaag     1200

accuucucca acggcuguga cuaugucagc aauaaaggug uggacacugu cucugugggg     1260

aacacgcuuu acuauguuaa uaagcaagag ggacagucac uguacgugaa aggcgagccu     1320

auuauaaacu uuuaugaucc auugguauuc ccgagugacg aauuugaugc uagcaucucc     1380

caggucaaug agaagauuaa ccagucucuc gccuucaucc ggaaaucgga cgaacuguua     1440

cacaacguga augcgggcaa gagcacaacc aacaucauga uuacuaccau aaucauuguu     1500

aucauuguga uccugcuauc ccucauagcc gucgggcugc uuuuguacug caaggcacgc     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8274
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt4)

<400>  8274
gggagaaagc uuaccaugga gcugcugauc cugaaggcca acgccaucac caccauccug       60

accgccguga ccuucugcuu cgccagcggc cagaacauca ccgaggaguu cuaccagagc      120

accugcagcg ccgugagcaa gggcuaccug ggcgcccuga gaaccggcug guacaccagc      180

gugaucacca ucgagcugag caacaucaag gagaucaagu gcaacggcac cgacgccaag      240

gugaagcuga ucaagcagga gcuggacaag uacaagaacg ccgugaccga ccugcagcug      300

cugaugcaga gcacccccgc caccggcagc ggcagcgcca ucgccagcgg cguggccgug      360

ugcaaggugc ugcaccugga gggcgaggug aacaagauca agagcgcccu gcugagcacc      420

aacaaggccg uggugagccu gagcggcugc ggcgugagcg ugcugaccuu caaggugcug      480

gaccugaaga acuacaucga caagcagcug cugcccaucc ugaacaagca gagcugcagc      540

auccccaaca ucgagaccgu gaucgaguuc cagcagaaga acaacagacu gcuggagauc      600

accagagagu ucagcgugaa cgccggcgug accacccccg ugagcaccua caugcugacc      660

aacagcgagc ugcugagccu gaucaacgac augcccauca ccaacgacca gaagaagcug      720

augagcaaca acgugcagau cgugagacag cagagcuaca gcaucaugug caucaucaag      780

gaggaggugc uggccuacgu ggugcagcug ccccuguacg gcgugaucga cacccccugc      840

uggaagcugc acaccagccc ccugugcacc accaacacca aggagggcag caacaucugc      900

cugaccagaa ccgacagagg cugguacugc gacaacgccg gcagcgugag cuucuucccc      960

caggccgaga ccugcaaggu gcagagcaac agaguguucu gcgacaccau gaacagccug     1020

acccugccca gcgaggugaa ccugugcaac guggacaucu ucaaccccaa guacgacugc     1080

aagaucauga ccagcaagac cgacgugagc agcagcguga ucaccagccu gggcgccauc     1140

gugagcugcu acggcaagac caagugcacc gccagcaaca agugcagagg caucaucaag     1200

accuucagca acggcugcga cuacgugagc aacaagggcg uggacaccgu gagcgugggc     1260

aacacccugu acuacgugaa caagcaggag ggccagagcc uguacgugaa gggcgagccc     1320

aucaucaacu ucuacgaccc ccugguguuc cccagcgacg aguucgacgc cagcaucagc     1380

caggugaacg agaagaucaa ccagagccug gccuucauca gaaagagcga cgagcugcug     1440

cacaacguga acgccggcaa gagcaccacc aacaucauga ucaccaccau caucaucgug     1500

aucaucguga uccugcugag ccugaucgcc gugggccugc ugcuguacug caaggccaga     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8275
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt5)

<400>  8275
gggagaaagc uuaccaugga gcugcucauc cugaaggcca acgcuauuac cacaauccuu       60

acggccguga ccuucugcuu ugcgagcggc cagaauauua cagaagaguu cuaccaaucc      120

accuguucug cugucagcaa aggguaucug ggagcccuca gaacaggcug guacaccucc      180

guuaucacaa uugaacuguc uaacaucaag gagaucaaau gcaaugggac cgacgccaag      240

gugaaacuua uuaagcagga acuggauaag uauaaaaacg cugugacgga ccuccagcug      300

cugaugcaga gcacccccgc cacaggaucc ggcucugcua ucgccagcgg ggucgcggug      360

uguaagguuc uccaccugga gggagaggug aauaaaauua aguccgcccu ucugagcacc      420

aacaaagcug ucgugucucu cuccggcugc ggcguuagcg ugcugacauu uaagguccuu      480

gaucugaaga auuacaucga caaacaacuc cugccuauuc ugaacaagca gucuuguucc      540

aucccgaaua uugaaaccgu gaucgaguuc cagcagaaaa acaaucggcu ccuggaaauc      600

acgcgcgagu uuagcgugaa cgccgggguc acaacccccg uuucuacaua uaugcuuacc      660

aauuccgagc ugcucagccu gauuaacgau augccuauca ccaaugacca aaagaaacuu      720

auguccaaca acgugcagau ugugagacag cagucuuaca gcaucaugug cauuaucaag      780

gaagaggucc uggcuuaugu gguucaacuc ccccuguacg gagugaucga uacaccuugu      840

uggaaacugc auacgagccc ccucugcacc acaaauacca aggaaggcag caacauuugu      900

cugacacgga ccgaccgcgg gugguacugc gauaaugccg gaucugucuc cuucuuuccu      960

caggcggaga cguguaaggu gcagagcaac agaguuuucu gcgacacaau gaacucucuu     1020

acccugccga gcgaagugaa ucucugcaau gucgauaucu uuaaccccaa auaugacugu     1080

aagauuauga ccuccaaaac agaugugucu agcuccguca ucaccagccu gggcgccauu     1140

gugucuugcu acgggaagac aaaauguacg gcuuccaaua agugccgggg aaucaucaag     1200

accuucagca acggcuguga cuauguuucu aauaaaggcg uggacacagu cuccgugggg     1260

aacacccuuu acuauguuaa uaagcaagag ggacagagcc uguacgugaa aggcgagccu     1320

auuaucaacu uuuaugaucc ccucgucuuc ccuuccgacg aauuugaugc cucuauuagc     1380

caggugaaug agaagaucaa ccagucccug gcuuucauuc gcaaaucuga cgaacugcuc     1440

cacaacguga augccgggaa guccacaacc aacaucauga uuacgaccau caucauuguu     1500

aucauuguca uccugcuuuc ccugauugcc gugggacucc ugcuguacug caaggcuaga     1560

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8276
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt6)

<400>  8276
gggagaaagc uuaccaugga acuacucaua uugaaagcca acgcaaucac aacaauacua       60

accgccguaa cauuuugcuu cgcgucaggc caaaauauaa cagaagaauu uuaccaauca      120

acaugcuccg ccguaucaaa aggauaccua ggugcauuac gaaccgguug guacacauca      180

guaaucacaa uagaacuuuc caacauuaaa gaaauaaaau gcaauggcac agacgcaaaa      240

gucaaacuaa uaaaacaaga acuagacaaa uauaaaaacg ccgucacaga cuuacaacua      300

uuaaugcaaa gcacaccagc aacaggaucc ggaucagcaa uagcaucagg aguagccguc      360

uguaaaguac uacaccuaga aggcgaaguu aauaaaauua aaucagcuuu auuaucaacc      420

aacaaagcag uaguaucacu auccggaugc ggagucuccg uccuaacauu caaaguacua      480

gaccucaaga auuacauaga uaaacaacua cuaccaauac ucaacaaaca aucauguuca      540

auaccaaaca ucgaaaccgu cauagaauuu caacaaaaaa auaauagacu cuuagaaaua      600

acacgagaau uuagcguaaa cgcaggaguc acaaccccug ucucaacaua caugcuaacc      660

aauuccgaau uauuaucacu cauaaaugac augccaauaa cuaaugacca aaaaaaacuu      720

augucaaaca acguacaaau aguaagacaa caaucauauu caauaaugug cauaaucaaa      780

gaagaaguuu uagcauaugu aguacaacua ccacuauaug gcgucauaga cacaccaugc      840

uggaaauuac acacaucacc ucuaugcaca acaaacacaa aagaaggaag caacauuugc      900

cuaaccagaa ccgauagagg augguacugc gauaacgcag gcucaguauc auucuucccu      960

caagccgaaa cuugcaaagu ccaaucaaau agagucuucu gcgauacaau gaacuccuua     1020

acuuuaccau cagaaguaaa ucuaugcaac guagauaucu uuaauccaaa auacgauugc     1080

aaaaucauga caucaaaaac agauguauca ucuaguguaa uuaccucccu aggagcaaua     1140

guaagcugcu acggaaaaac aaaaugcacc gccucuaaca aaugucgugg aauaauaaaa     1200

acauucucaa acggaugcga uuauguauca aauaaaggug ucgacaccgu aucaguaggc     1260

aauacacuau acuauguaaa uaaacaagaa ggacaaucac ucuacgucaa aggugaacca     1320

auaauaaacu ucuacgaccc acuuguauuc ccaagcgacg aauuugacgc aucaauaagc     1380

caaguaaacg aaaaaauaaa ccaaucacua gcauucauca gaaaaucaga cgaacuacuc     1440

cacaauguaa augcaggaaa aucaacaacc aauaucauga uaacaaccau aauaauaguc     1500

auaauaguaa uacuauuauc ccucauagcc guuggacuac uccuauauug uaaagcacga     1560

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8277
<211>  1765
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1_mut8 (opt11)

<400>  8277
gggagaaagc uuaccaugga acuccucauc cucaaagcca acgccaucac caccauacuc       60

accgcaguaa ccuucugcuu cgcauccggc caaaacauca cagaagaguu cuaccagagu      120

accugcuccg ccgucuccaa aggcuaccuu ggcgcccucc guaccgggug guacacaucc      180

gucaucacaa ucgaacucuc caacaucaaa gaaauaaagu gcaacggcac agacgccaaa      240

guaaaacuga uaaagcaaga acucgacaaa uacaaaaacg ccguaaccga ccuccagcua      300

cuaaugcaau ccacucccgc caccggcagc ggauccgcca ucgccuccgg aguagccguc      360

uguaaagucu uacaccucga aggcgaagug aacaaaauca aauccgcccu acucucaacc      420

aacaaagccg uaguaucacu cuccgggugc ggcguuucag ugcuaacguu caaaguccuu      480

gaccucaaaa acuacaucga caaacaacuc cuccccaucc uaaauaaaca auccugcucc      540

auacccaaca ucgagacugu caucgaguuc cagcagaaaa acaaccgacu ccucgaaauc      600

acacgcgagu ucucugucaa cgccggcguc acaacccccg ucuccacaua caugcucacc      660

aacagcgaac uccucucccu aaucaaugac augcccauca ccaacgacca aaagaaacuc      720

augucaaaca acguccaaau cguccgccaa caauccuaca gcaucaugug caucaucaaa      780

gaagaaguuc ucgcauacgu aguacaacuc ccccucuacg gagugaucga cacccccugc      840

uggaaacuac acaccagccc gcuuugcacc acaaacacca aggaaggcuc caacaucugc      900

cucacucgaa ccgaccgcgg cugguacugc gacaacgcag gcuccgucag uuucuuuccc      960

caagcagaaa caugcaaagu ccaauccaac cgaguauucu gcgacaccau gaacucccuc     1020

acccuaccau ccgaaguuaa ccuaugcaac guggacaucu ucaaccccaa guacgacugc     1080

aaaauuauga ccuccaaaac cgacguaucc uccagcguca ucaccagccu cggagcaaua     1140

gucuccugcu acggcaagac caagugcacc gcuuccaaca agugucgcgg aaucaucaaa     1200

accuucucaa acggcugcga cuacgucucc aacaaaggcg ucgacaccgu auccguagga     1260

aacacccuau acuacgucaa caaacaagaa ggacaauccc ucuaugucaa aggcgaaccc     1320

aucaucaauu ucuacgaccc ccuagucuuc ccuuccgacg aguucgacgc guccaucagc     1380

caagucaaug aaaagaucaa ccagagccug gcauucaucc gcaaauccga cgaacuccuc     1440

cacaacguca acgcgggaaa auccacgaca aacaucauga ucaccaccau caucaucguc     1500

aucauaguca uucuccuuuc ucucaucgcc gugggacuac uucucuacug caaagcccga     1560

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1620

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1740

ggcucuuuuc agagccacca gaauu                                           1765


<210>  8278
<211>  2068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-4 comprising derived and/or modified 
       sequence from HRSV(A2)__F-del_DSCav1 (opt1) R4745/R5717

<400>  8278
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagcugcuca uccugaaggc caacgccauc accaccaucc      120

ugacggcggu gaccuucugc uucgccagcg gccagaacau caccgaggag uucuaccagu      180

ccacgugcag cgccgucucc aagggguacc ucagcgcccu gcggaccggc ugguacaccu      240

ccgugaucac caucgagcug agcaacauca aggagaacaa gugcaacggg accgacgcca      300

aggugaagcu caucaagcag gagcuggaca aguacaagaa cgcggucacg gagcugcagc      360

uccugaugca guccaccccg gcaaccaaca accgcgcccg gcgcgagcug ccccgguuca      420

ugaacuacac ccucaacaac gccaagaaga cgaacgugac ccugagcaag aagcgcaagc      480

ggcgcuuccu gggcuuccuc cugggggugg gcuccgccau cgcgagcggc gucgccgugu      540

gcaaggugcu gcaccucgag ggggagguca acaagaucaa gagcgcccug cuguccacca      600

acaaggccgu ggugagccuc uccaacggcg ucagcgugcu gaccuucaag gugcuggacc      660

ucaagaacua caucgacaag cagcugcugc ccauccugaa caagcagagc ugcuccauca      720

gcaacaucga gacggugauc gaguuccagc agaagaacaa ccggcuccug gagaucaccc      780

gcgaguucag cgugaacgcc ggggucacca cccccguguc cacguacaug cugaccaaca      840

gcgagcuccu gucccugauc aacgacaugc cgaucaccaa cgaccagaag aagcucauga      900

gcaacaacgu gcagaucguc cggcagcagu ccuacagcau caugugcauc aucaaggagg      960

aggugcuggc guacgugguc cagcugcccc ucuacggcgu gaucgacacc cccugcugga     1020

agcugcacac gagcccccug ugcaccacca acaccaagga gggguccaac aucugccuca     1080

cgcgcaccga ccggggcugg uacugcgaca acgccggcag cgucuccuuc uucccgcagg     1140

ccgagaccug caaggugcag agcaaccgcg uguucugcga caccaugaac ucccugacgc     1200

ugcccagcga gguaaaccuc ugcaacgucg acaucuucaa ccccaaguac gacugcaaga     1260

ucaugaccuc caagaccgac gugagcucca gcgugaucac cucccugggg gccaucguca     1320

gcugcuacgg caagacgaag ugcaccgcca gcaacaagaa ccgggggauc aucaagaccu     1380

ucuccaacgg cugcgacuac gugagcaaca agggcgugga caccgugucc gucgggaaca     1440

cccuguacua cgugaacaag caggagggca agagccucua cgugaagggg gagcccauca     1500

ucaacuucua cgacccgcug gucuuccccu ccgacgaguu cgacgcgagc aucucccagg     1560

ugaacgagaa gaucaaccag agccuggccu ucauccgcaa guccgacgag cugcuccaca     1620

acgugaacgc cggcaagagc acgaccaaca ucaugaucac caccaucauc aucgucauca     1680

ucgugauccu gcugucccuc aucgccgugg ggcugcugcu cuacugcaag gcccggugag     1740

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1800

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1860

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1920

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2040

aaaggcucuu uucagagcca ccagaauu                                        2068


<210>  8279
<211>  589
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44801.1__F0

<400>  8279

Met Ile Pro Gln Ala Arg Thr Lys Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser Lys 
                565                 570                 575     


Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
            580                 585                 


<210>  8280
<211>  589
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44759.1__F0

<400>  8280

Met Ile Pro Gln Ala Arg Thr Lys Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Arg Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser Lys 
                565                 570                 575     


Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
            580                 585                 


<210>  8281
<211>  589
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44661.1__F0

<400>  8281

Met Ile Pro Gln Ala Arg Thr Glu Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Glu Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser Lys 
                565                 570                 575     


Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
            580                 585                 


<210>  8282
<211>  589
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44602.1__F0

<400>  8282

Met Ile Pro Gln Ala Arg Thr Glu Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser Lys 
                565                 570                 575     


Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
            580                 585                 


<210>  8283
<211>  575
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__2207424A__F0

<400>  8283

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Ser 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 575 


<210>  8284
<211>  575
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38520.1__F0

<400>  8284

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Leu Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 575 


<210>  8285
<211>  575
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38517.1__F0

<400>  8285

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Thr Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Ser 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 575 


<210>  8286
<211>  575
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38519.1__F0

<400>  8286

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Val Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Ile Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Thr Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Leu Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 575 


<210>  8287
<211>  575
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38518.1__F0

<400>  8287

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Thr Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Thr Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Ser 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Trp Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 575 


<210>  8288
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93587.1__F0

<400>  8288

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Val Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8289
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93599.1__F0

<400>  8289

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Val 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Thr Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8290
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93571.1__F0

<400>  8290

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Phe Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Phe Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8291
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93568.1__F0

<400>  8291

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Thr Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8292
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93589.1__F0

<400>  8292

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Val Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8293
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93597.1__F0

<400>  8293

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Val Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8294
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93563.1__F0

<400>  8294

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Cys Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Leu Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8295
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93594.1__F0

<400>  8295

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8296
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93601.1__F0

<400>  8296

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Asn Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8297
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93562.1__F0

<400>  8297

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Ser Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Gly Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Met Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8298
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93561.1__F0

<400>  8298

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Gly Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8299
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93607.1__F0

<400>  8299

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asn Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8300
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93588.1__F0

<400>  8300

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8301
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93575.1__F0

<400>  8301

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Val Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8302
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93468.1__F0

<400>  8302

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Pro Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Ile Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8303
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93467.1__F0

<400>  8303

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Glu Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8304
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93590.1__F0

<400>  8304

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8305
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93552.1__F0

<400>  8305

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Leu 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8306
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93556.1__F0

<400>  8306

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asn 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8307
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93471.1__F0

<400>  8307

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Arg Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8308
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93458.1__F0

<400>  8308

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8309
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93494.1__F0

<400>  8309

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Ile Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Ile Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8310
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93470.1__F0

<400>  8310

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Ser Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ala Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8311
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93489.1__F0

<400>  8311

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Val Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8312
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93542.1__F0

<400>  8312

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Ser Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8313
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93472.1__F0

<400>  8313

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ser Ser Ser Gln Asn Ile Thr Glu Lys Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Lys Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu His Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Pro Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ile Lys Lys Arg Lys Arg Thr Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Gln Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8314
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93514.1__F0

<400>  8314

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8315
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93485.1__F0

<400>  8315

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Lys Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Asn Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8316
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93533.1__F0

<400>  8316

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Ile His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8317
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93481.1__F0

<400>  8317

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Thr Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Ile Gly Ala Ile Val Ser Trp 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Cys Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Ile Ser Cys Lys Ala Arg Ser Pro Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8318
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93546.1__F0

<400>  8318

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8319
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93512.1__F0

<400>  8319

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Leu Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8320
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93554.1__F0

<400>  8320

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Met Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8321
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93551.1__F0

<400>  8321

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8322
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93547.1__F0

<400>  8322

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8323
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93558.1__F0

<400>  8323

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Tyr Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Ile Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8324
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93461.1__F0

<400>  8324

Met Glu Ser Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8325
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93500.1__F0

<400>  8325

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Ile Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8326
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93426.1__F0

<400>  8326

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Tyr Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8327
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93398.1__F0

<400>  8327

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8328
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93401.1__F0

<400>  8328

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Tyr Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8329
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93361.1__F0

<400>  8329

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Ala Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8330
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93408.1__F0

<400>  8330

Met Glu Leu Pro Ile Ser Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asn Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8331
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93443.1__F0

<400>  8331

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8332
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93429.1__F0

<400>  8332

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8333
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93359.1__F0

<400>  8333

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Ser Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8334
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93365.1__F0

<400>  8334

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Val Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8335
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93366.1__F0

<400>  8335

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Ile Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8336
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93402.1__F0

<400>  8336

Met Glu Leu Pro Ile Leu Lys Thr Asn Thr Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ile Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Asn Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8337
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93377.1__F0

<400>  8337

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8338
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93412.1__F0

<400>  8338

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ile Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Ser Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asn Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8339
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93391.1__F0

<400>  8339

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Ser Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8340
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93457.1__F0

<400>  8340

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Ile Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8341
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93372.1__F0

<400>  8341

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asn Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8342
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93455.1__F0

<400>  8342

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8343
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93364.1__F0

<400>  8343

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Ile Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8344
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93378.1__F0

<400>  8344

Met Gln Leu Pro Ile Leu Lys Ile Tyr Ala Ile Thr Ser Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Tyr Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8345
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93393.1__F0

<400>  8345

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Lys Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8346
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93362.1__F0

<400>  8346

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8347
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93585.1__F0

<400>  8347

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Val 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8348
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28504.1__F0

<400>  8348

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8349
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93404.1__F0

<400>  8349

Met Glu Leu Pro Ile Ser Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8350
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS49123.1__F0

<400>  8350

Met Glu Leu Pro Ile Leu Lys Thr Asn Thr Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8351
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN92837.1__F0

<400>  8351

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8352
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48496.1__F0

<400>  8352

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8353
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78271.1__F0

<400>  8353

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8354
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY62428.1__F0

<400>  8354

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8355
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57174.1__F0

<400>  8355

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Lys Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8356
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81390.1__F0

<400>  8356

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8357
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81506.1__F0

<400>  8357

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8358
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60128.1__F0

<400>  8358

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8359
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60129.1__F0

<400>  8359

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8360
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63389.1__F0

<400>  8360

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8361
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB66328.1__F0

<400>  8361

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Arg Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Ser Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Thr Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8362
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80034.1__F0

<400>  8362

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Ser Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8363
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91253.1__F0

<400>  8363

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8364
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P03420.1__F0

<400>  8364

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Pro Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Ile Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Met Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8365
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIO08046.1__F0

<400>  8365

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8366
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX95851.1__F0

<400>  8366

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Gly 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Asn Asn 
                565                 570                 


<210>  8367
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__NP_056863.1__F0

<400>  8367

Met Glu Leu Leu Ile His Arg Leu Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Asn Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8368
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60234.1__F0

<400>  8368

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8369
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60231.1__F0

<400>  8369

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Arg Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8370
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60232.1__F0

<400>  8370

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8371
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60222.1__F0

<400>  8371

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Ile Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ile Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8372
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60219.1__F0

<400>  8372

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8373
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60215.1__F0

<400>  8373

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8374
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60214.1__F0

<400>  8374

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8375
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60212.1__F0

<400>  8375

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8376
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60208.1__F0

<400>  8376

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8377
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60202.1__F0

<400>  8377

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8378
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60220.1__F0

<400>  8378

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Ile Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8379
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60213.1__F0

<400>  8379

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8380
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60190.1__F0

<400>  8380

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Phe 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8381
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60187.1__F0

<400>  8381

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ser Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8382
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60201.1__F0

<400>  8382

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8383
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60173.1__F0

<400>  8383

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Ser Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8384
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60169.1__F0

<400>  8384

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ser Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8385
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60162.1__F0

<400>  8385

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Phe 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8386
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60156.1__F0

<400>  8386

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ile Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8387
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60151.1__F0

<400>  8387

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Leu Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8388
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60150.1__F0

<400>  8388

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8389
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60148.1__F0

<400>  8389

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Leu Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8390
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60127.1__F0

<400>  8390

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8391
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60137.1__F0

<400>  8391

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Lys Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8392
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60135.1__F0

<400>  8392

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8393
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46420.1__F0

<400>  8393

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Ile Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Phe Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8394
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60200.1__F0

<400>  8394

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Val Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8395
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46419.1__F0

<400>  8395

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Ile Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8396
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46417.1__F0

<400>  8396

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Thr Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8397
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46413.1__F0

<400>  8397

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8398
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46414.1__F0

<400>  8398

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8399
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46410.1__F0

<400>  8399

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Thr Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Ile Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8400
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46403.1__F0

<400>  8400

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8401
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46409.1__F0

<400>  8401

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Thr Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8402
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99061.1__F0

<400>  8402

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8403
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95400.1__F0

<400>  8403

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Asn Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8404
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46401.1__F0

<400>  8404

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Ile Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8405
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99064.1__F0

<400>  8405

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8406
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95376.1__F0

<400>  8406

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asn Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8407
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60138.1__F0

<400>  8407

Met Glu Leu Pro Ile Leu Lys Thr Asn Ser Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8408
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99060.1__F0

<400>  8408

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8409
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95365.1__F0

<400>  8409

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Tyr Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8410
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55563.1__F0

<400>  8410

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8411
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55530.1__F0

<400>  8411

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Ser Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Ile Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8412
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55442.1__F0

<400>  8412

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Glu Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8413
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55420.1__F0

<400>  8413

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Val Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8414
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55552.1__F0

<400>  8414

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8415
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55365.1__F0

<400>  8415

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Ile His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8416
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99059.1__F0

<400>  8416

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8417
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55354.1__F0

<400>  8417

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8418
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55343.1__F0

<400>  8418

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Ala Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8419
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55387.1__F0

<400>  8419

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ile Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Ala Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8420
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55299.1__F0

<400>  8420

Met Asp Leu Pro Ile Leu Lys Thr Lys Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Asn Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8421
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55288.1__F0

<400>  8421

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8422
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55266.1__F0

<400>  8422

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8423
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55277.1__F0

<400>  8423

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8424
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55255.1__F0

<400>  8424

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Phe Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8425
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55222.1__F0

<400>  8425

Met Glu Leu Pro Ile Leu Lys Thr Asn Val Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8426
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55211.1__F0

<400>  8426

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8427
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55244.1__F0

<400>  8427

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8428
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFI25262.1__F0

<400>  8428

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ser Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8429
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34266.1__F0

<400>  8429

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8430
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55332.1__F0

<400>  8430

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8431
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34264.1__F0

<400>  8431

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Gly Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Glu Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8432
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34262.1__F0

<400>  8432

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr His Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8433
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34265.1__F0

<400>  8433

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Ser 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Ala Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8434
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34261.1__F0

<400>  8434

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Gly Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8435
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34260.1__F0

<400>  8435

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8436
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34259.1__F0

<400>  8436

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Met Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8437
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63641.1__F0

<400>  8437

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Phe Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8438
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63487.1__F0

<400>  8438

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8439
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63520.1__F0

<400>  8439

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8440
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__4CCF_A__F0

<400>  8440

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Val Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8441
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63334.1__F0

<400>  8441

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8442
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45949.1__F0

<400>  8442

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8443
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45939.1__F0

<400>  8443

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Phe Ile Asp Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8444
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63312.1__F0

<400>  8444

Met Glu Leu Pro Val Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8445
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63586.1__F0

<400>  8445

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8446
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45919.1__F0

<400>  8446

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8447
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45909.1__F0

<400>  8447

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Val Ile 
545                 550                 555                 560 


Asn Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8448
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45889.1__F0

<400>  8448

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Val Ile 
545                 550                 555                 560 


Asp Asp Tyr Leu Ser Gly Ile Asn Asn Ile Ser Phe Ile Tyr 
                565                 570                 


<210>  8449
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45879.1__F0

<400>  8449

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8450
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45869.1__F0

<400>  8450

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8451
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45929.1__F0

<400>  8451

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8452
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45850.1__F0

<400>  8452

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8453
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45859.1__F0

<400>  8453

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8454
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63444.1__F0

<400>  8454

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8455
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO23054.1__F0

<400>  8455

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Thr Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8456
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO23052.1__F0

<400>  8456

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Ser Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8457
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45830.1__F0

<400>  8457

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8458
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45840.1__F0

<400>  8458

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Val Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8459
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO23051.1__F0

<400>  8459

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8460
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEC32087.1__F0

<400>  8460

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8461
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95785.1__F0

<400>  8461

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Glu 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8462
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEC32085.1__F0

<400>  8462

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Thr Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Gly Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Lys Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8463
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95784.1__F0

<400>  8463

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Gln 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8464
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95783.1__F0

<400>  8464

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Thr 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8465
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95782.1__F0

<400>  8465

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Met 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8466
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95781.1__F0

<400>  8466

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Asn 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8467
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95778.1__F0

<400>  8467

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Ser Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Phe Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8468
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACY68435.1__F0

<400>  8468

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Thr Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8469
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACO83302.1__F0

<400>  8469

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8470
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABI35685.1__F0

<400>  8470

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Ala 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8471
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFI25251.1__F0

<400>  8471

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Met Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8472
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAX23994.1__F0

<400>  8472

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Asn 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Thr Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8473
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97026.1__F0

<400>  8473

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Gly Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8474
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAR14266.1__F0

<400>  8474

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Thr Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Ser Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8475
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97027.1__F0

<400>  8475

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Arg Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8476
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97030.1__F0

<400>  8476

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ala 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8477
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97028.1__F0

<400>  8477

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Glu Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8478
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAC57027.1__F0

<400>  8478

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8479
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97029.1__F0

<400>  8479

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Leu Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8480
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97031.1__F0

<400>  8480

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8481
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM68160.1__F0

<400>  8481

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8482
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM44851.1__F0

<400>  8482

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8483
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P11209.2__F0

<400>  8483

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asp Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8484
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P13843.1__F0

<400>  8484

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Val Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Arg Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Met Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8485
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAO72325.1__F0

<400>  8485

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Ala Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu His Leu Lys Asn Tyr Ile Asp Lys Gln Phe Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Met Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8486
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM68157.1__F0

<400>  8486

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8487
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__CAA26143.1__F0

<400>  8487

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Phe Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8488
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__1512372A__F0

<400>  8488

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asp 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Ala Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8489
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB86664.1__F0

<400>  8489

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8490
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAO72324.1__F0

<400>  8490

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Phe Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8491
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB82446.1__F0

<400>  8491

Met Glu Leu Leu Ile His Arg Leu Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Gly Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Asn Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8492
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAO72323.1__F0

<400>  8492

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Met Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8493
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM68154.1__F0

<400>  8493

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Ile Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Cys Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8494
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAA47410.1__F0

<400>  8494

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8495
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P12568.1__F0

<400>  8495

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Ala Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8496
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB07894.1__F0

<400>  8496

Met Glu Leu Leu Ile His Arg Leu Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Asn Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Tyr Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8497
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39517.1__F0

<400>  8497

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8498
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54612.1__F0

<400>  8498

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Ile Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8499
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54636.1__F0

<400>  8499

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Leu Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8500
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54627.1__F0

<400>  8500

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Gly Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Ser Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8501
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54621.1__F0

<400>  8501

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Thr Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8502
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54570.1__F0

<400>  8502

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ser Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8503
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54579.1__F0

<400>  8503

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8504
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54595.1__F0

<400>  8504

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8505
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54555.1__F0

<400>  8505

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Leu Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8506
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54552.1__F0

<400>  8506

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ala Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8507
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54564.1__F0

<400>  8507

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Ile Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8508
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54581.1__F0

<400>  8508

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Ser Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8509
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54571.1__F0

<400>  8509

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Leu Met Asn Tyr Thr Leu Lys Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8510
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54553.1__F0

<400>  8510

Met Glu Leu Leu Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Ile Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8511
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54565.1__F0

<400>  8511

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Met Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Ala Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8512
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54245.1__F0

<400>  8512

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Gln 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Ile Gln Pro 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8513
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54243.1__F0

<400>  8513

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Ser Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8514
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54238.1__F0

<400>  8514

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Lys Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8515
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54242.1__F0

<400>  8515

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Ile Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8516
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54239.1__F0

<400>  8516

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Tyr Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8517
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54235.1__F0

<400>  8517

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Val Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asp Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8518
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54234.1__F0

<400>  8518

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Asp Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8519
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54236.1__F0

<400>  8519

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8520
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54244.1__F0

<400>  8520

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Val Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Asp Asn Ser Arg Ala Arg Lys Glu Gln Pro 
            100                 105                 110         


Arg Phe Ile Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Met His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8521
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54186.1__F0

<400>  8521

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Arg Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8522
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54178.1__F0

<400>  8522

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asp Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8523
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54202.1__F0

<400>  8523

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu His Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8524
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54151.1__F0

<400>  8524

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Val Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8525
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54142.1__F0

<400>  8525

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Phe Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8526
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54134.1__F0

<400>  8526

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8527
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54170.1__F0

<400>  8527

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8528
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54210.1__F0

<400>  8528

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Val Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8529
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54169.1__F0

<400>  8529

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8530
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54213.1__F0

<400>  8530

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8531
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54203.1__F0

<400>  8531

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8532
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54160.1__F0

<400>  8532

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Ser Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8533
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54163.1__F0

<400>  8533

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Val Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8534
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54215.1__F0

<400>  8534

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8535
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54156.1__F0

<400>  8535

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Val Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Ile Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8536
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54179.1__F0

<400>  8536

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Gly Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Arg Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8537
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54150.1__F0

<400>  8537

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8538
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54207.1__F0

<400>  8538

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asp Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8539
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54194.1__F0

<400>  8539

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Tyr Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8540
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54149.1__F0

<400>  8540

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn His Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8541
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54138.1__F0

<400>  8541

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Ile Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8542
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54199.1__F0

<400>  8542

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Thr Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Glu Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8543
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54220.1__F0

<400>  8543

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Val Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8544
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54181.1__F0

<400>  8544

Met Glu Leu Pro Ile Ile Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8545
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54132.1__F0

<400>  8545

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Ile Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8546
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54146.1__F0

<400>  8546

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Ile Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8547
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54122.1__F0

<400>  8547

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Ile Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8548
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54124.1__F0

<400>  8548

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Ser Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8549
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35202.1__F0

<400>  8549

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8550
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35201.1__F0

<400>  8550

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Ser Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8551
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35192.1__F0

<400>  8551

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Tyr Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8552
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35193.1__F0

<400>  8552

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Arg Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8553
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35204.1__F0

<400>  8553

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Gly Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8554
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35199.1__F0

<400>  8554

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Leu Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8555
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35184.1__F0

<400>  8555

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8556
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35126.1__F0

<400>  8556

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8557
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35133.1__F0

<400>  8557

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ser Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8558
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35130.1__F0

<400>  8558

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8559
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35160.1__F0

<400>  8559

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Thr Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8560
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35162.1__F0

<400>  8560

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Thr Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Thr Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8561
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35181.1__F0

<400>  8561

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Thr Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Ile Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8562
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35165.1__F0

<400>  8562

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Phe Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8563
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35121.1__F0

<400>  8563

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8564
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35173.1__F0

<400>  8564

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Lys Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8565
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35138.1__F0

<400>  8565

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8566
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35176.1__F0

<400>  8566

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asp Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8567
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35142.1__F0

<400>  8567

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8568
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35136.1__F0

<400>  8568

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8569
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35153.1__F0

<400>  8569

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Thr 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8570
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35115.1__F0

<400>  8570

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8571
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35150.1__F0

<400>  8571

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8572
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35097.1__F0

<400>  8572

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8573
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35109.1__F0

<400>  8573

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Met Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8574
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35094.1__F0

<400>  8574

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8575
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35183.1__F0

<400>  8575

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Thr Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Val Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8576
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35104.1__F0

<400>  8576

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Met Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8577
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35099.1__F0

<400>  8577

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ser Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8578
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35188.1__F0

<400>  8578

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Tyr Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ser Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8579
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45871.1__F0

<400>  8579

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8580
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASV65838.1__F0

<400>  8580

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8581
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39373.1__F0

<400>  8581

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Ser Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8582
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AII22107.1__F0

<400>  8582

Met Glu Leu Leu Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8583
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39400.1__F0

<400>  8583

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8584
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21375.1__F0

<400>  8584

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8585
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39457.1__F0

<400>  8585

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8586
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29240.1__F0

<400>  8586

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Ile Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8587
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29251.1__F0

<400>  8587

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Val Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8588
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29189.1__F0

<400>  8588

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asp Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8589
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29207.1__F0

<400>  8589

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Glu Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8590
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUH15164.1__F0

<400>  8590

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Glu Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8591
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV81343.1__F0

<400>  8591

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8592
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68654.1__F0

<400>  8592

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8593
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68577.1__F0

<400>  8593

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Val Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Asp Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8594
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68566.1__F0

<400>  8594

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asn Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8595
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68555.1__F0

<400>  8595

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8596
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68478.1__F0

<400>  8596

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Ala Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Val Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8597
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68445.1__F0

<400>  8597

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Ser Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8598
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68500.1__F0

<400>  8598

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8599
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68522.1__F0

<400>  8599

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Ile Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8600
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68291.1__F0

<400>  8600

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Thr Ile Val Ile Thr Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8601
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68149.1__F0

<400>  8601

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8602
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68094.1__F0

<400>  8602

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ala Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Pro His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8603
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67097.1__F0

<400>  8603

Met Glu Leu Leu Ile His Arg Ser Ser Ala Val Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Arg Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8604
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66866.1__F0

<400>  8604

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8605
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66580.1__F0

<400>  8605

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8606
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95750.1__F0

<400>  8606

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Ile Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8607
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95541.1__F0

<400>  8607

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8608
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95519.1__F0

<400>  8608

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8609
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21419.1__F0

<400>  8609

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ala Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8610
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21331.1__F0

<400>  8610

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8611
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21165.1__F0

<400>  8611

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Asp Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8612
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21143.1__F0

<400>  8612

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8613
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21132.1__F0

<400>  8613

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8614
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39478.1__F0

<400>  8614

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8615
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV93506.1__F0

<400>  8615

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ala Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Met Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8616
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV93509.1__F0

<400>  8616

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ile Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8617
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95717.1__F0

<400>  8617

Met Glu Leu Pro Thr Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Val Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8618
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV81354.1__F0

<400>  8618

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8619
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28317.1__F0

<400>  8619

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Gly Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Lys Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Ile Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8620
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBA57901.1__F0

<400>  8620

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Arg Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Met Val Asn 
        195                 200                 205             


Arg Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8621
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASZ70099.1__F0

<400>  8621

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Asn Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8622
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28361.1__F0

<400>  8622

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Val Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8623
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AQX36844.1__F0

<400>  8623

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Ala Gln Ser Asn Arg Val Phe Asn Asn 
        355                 360                 365             


Thr Ile Thr Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8624
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASK05520.1__F0

<400>  8624

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8625
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28427.1__F0

<400>  8625

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Glu Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8626
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28297.1__F0

<400>  8626

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ser Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8627
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28328.1__F0

<400>  8627

Met Asp Ser Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8628
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARQ15966.1__F0

<400>  8628

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Tyr Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8629
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARN61507.1__F0

<400>  8629

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Gly Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asp 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Leu Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8630
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARA15413.1__F0

<400>  8630

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Lys Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8631
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39394.1__F0

<400>  8631

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8632
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78845.1__F0

<400>  8632

Met Glu Leu Leu Ile His Arg Pro Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8633
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78867.1__F0

<400>  8633

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Arg Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8634
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78900.1__F0

<400>  8634

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Cys Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8635
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78878.1__F0

<400>  8635

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Gln Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8636
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78779.1__F0

<400>  8636

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8637
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78702.1__F0

<400>  8637

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Ser Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Leu Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8638
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78713.1__F0

<400>  8638

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Lys Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8639
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78680.1__F0

<400>  8639

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8640
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78658.1__F0

<400>  8640

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Trp Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8641
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78647.1__F0

<400>  8641

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Asn Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8642
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78636.1__F0

<400>  8642

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8643
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48870.1__F0

<400>  8643

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Ser Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8644
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78614.1__F0

<400>  8644

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu Leu Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8645
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78905.1__F0

<400>  8645

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8646
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77402.1__F0

<400>  8646

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8647
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW29972.1__F0

<400>  8647

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Phe Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8648
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOZ15479.1__F0

<400>  8648

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Ser Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8649
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28484.1__F0

<400>  8649

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8650
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57240.1__F0

<400>  8650

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Gly Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Tyr Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8651
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57031.1__F0

<400>  8651

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Ile Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8652
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48980.1__F0

<400>  8652

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Ile Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8653
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48848.1__F0

<400>  8653

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Tyr Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8654
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48815.1__F0

<400>  8654

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8655
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48738.1__F0

<400>  8655

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Asn Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8656
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS49068.1__F0

<400>  8656

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Ile 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8657
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48727.1__F0

<400>  8657

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Ile Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8658
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48716.1__F0

<400>  8658

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ser Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8659
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48683.1__F0

<400>  8659

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Thr 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8660
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48551.1__F0

<400>  8660

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8661
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48485.1__F0

<400>  8661

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu His Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Glu Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8662
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48518.1__F0

<400>  8662

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Ile Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8663
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48463.1__F0

<400>  8663

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ile Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8664
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48441.1__F0

<400>  8664

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Gly Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8665
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48397.1__F0

<400>  8665

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Asp Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8666
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48375.1__F0

<400>  8666

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Ile Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8667
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48353.1__F0

<400>  8667

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8668
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48287.1__F0

<400>  8668

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ile 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8669
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48320.1__F0

<400>  8669

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Ile Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8670
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48265.1__F0

<400>  8670

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8671
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48254.1__F0

<400>  8671

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8672
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48221.1__F0

<400>  8672

Met Glu Leu Leu Ile Arg Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile His Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8673
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79638.1__F0

<400>  8673

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8674
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ALC74025.1__F0

<400>  8674

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8675
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69825.1__F0

<400>  8675

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8676
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81286.1__F0

<400>  8676

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8677
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40516.1__F0

<400>  8677

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ala Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8678
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40125.1__F0

<400>  8678

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Val Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Ser Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8679
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40104.1__F0

<400>  8679

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ile Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8680
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40082.1__F0

<400>  8680

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8681
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD39908.1__F0

<400>  8681

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ile Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8682
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44826.1__F0

<400>  8682

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Pro Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ile Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8683
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44506.1__F0

<400>  8683

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Ser Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8684
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44535.1__F0

<400>  8684

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8685
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80463.1__F0

<400>  8685

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asp Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8686
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80408.1__F0

<400>  8686

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Lys Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8687
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80397.1__F0

<400>  8687

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Asp Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8688
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80386.1__F0

<400>  8688

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8689
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80331.1__F0

<400>  8689

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Ile Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8690
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80320.1__F0

<400>  8690

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Tyr Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ile 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8691
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80364.1__F0

<400>  8691

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8692
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80276.1__F0

<400>  8692

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Val Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8693
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80221.1__F0

<400>  8693

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8694
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80188.1__F0

<400>  8694

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8695
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80144.1__F0

<400>  8695

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Ile Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8696
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80133.1__F0

<400>  8696

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Arg Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8697
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80111.1__F0

<400>  8697

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8698
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80122.1__F0

<400>  8698

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Ile Asn Leu Asn Ile Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8699
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80056.1__F0

<400>  8699

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Phe Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8700
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80012.1__F0

<400>  8700

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Tyr Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8701
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80067.1__F0

<400>  8701

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Gly Lys Arg Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8702
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79979.1__F0

<400>  8702

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8703
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79935.1__F0

<400>  8703

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8704
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79990.1__F0

<400>  8704

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Val Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8705
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79902.1__F0

<400>  8705

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Asn Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8706
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79759.1__F0

<400>  8706

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Ala Thr Val Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Lys Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8707
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79715.1__F0

<400>  8707

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Val Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8708
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79671.1__F0

<400>  8708

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8709
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79649.1__F0

<400>  8709

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Tyr Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8710
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AII22031.1__F0

<400>  8710

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8711
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79718.1__F0

<400>  8711

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8712
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79586.1__F0

<400>  8712

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Ser Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8713
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79553.1__F0

<400>  8713

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8714
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79542.1__F0

<400>  8714

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Ser Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8715
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79476.1__F0

<400>  8715

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Ser Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8716
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79388.1__F0

<400>  8716

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Val Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Val Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8717
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79201.1__F0

<400>  8717

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Ile Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8718
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79190.1__F0

<400>  8718

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Phe 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8719
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79157.1__F0

<400>  8719

Met Glu Leu Leu Ile Arg Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8720
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79124.1__F0

<400>  8720

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8721
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79091.1__F0

<400>  8721

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys His Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8722
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79047.1__F0

<400>  8722

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8723
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79014.1__F0

<400>  8723

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ala Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8724
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79003.1__F0

<400>  8724

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8725
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78872.1__F0

<400>  8725

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8726
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78832.1__F0

<400>  8726

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8727
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78689.1__F0

<400>  8727

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Ile Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8728
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78645.1__F0

<400>  8728

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Ile Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8729
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78513.1__F0

<400>  8729

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ser Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8730
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78480.1__F0

<400>  8730

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Ile Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8731
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78447.1__F0

<400>  8731

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Lys Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8732
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78392.1__F0

<400>  8732

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Val Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Thr Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8733
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78194.1__F0

<400>  8733

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Asn Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8734
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78084.1__F0

<400>  8734

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Thr Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8735
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78051.1__F0

<400>  8735

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asp Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8736
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77963.1__F0

<400>  8736

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Asp Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8737
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77908.1__F0

<400>  8737

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Ser Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8738
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77776.1__F0

<400>  8738

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Arg Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8739
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77710.1__F0

<400>  8739

Met Glu Leu Leu Ile Arg Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Arg Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Arg Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8740
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77501.1__F0

<400>  8740

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Asn 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8741
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77424.1__F0

<400>  8741

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Lys Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8742
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91385.1__F0

<400>  8742

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8743
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91264.1__F0

<400>  8743

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Ala Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8744
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91242.1__F0

<400>  8744

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8745
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57504.1__F0

<400>  8745

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Asn Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8746
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__CUS01881.1__F0

<400>  8746

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Thr Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8747
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__CUS01870.1__F0

<400>  8747

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asn Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8748
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67350.1__F0

<400>  8748

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8749
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67251.1__F0

<400>  8749

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Cys Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8750
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67262.1__F0

<400>  8750

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Val Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8751
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67229.1__F0

<400>  8751

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8752
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67196.1__F0

<400>  8752

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Glu Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8753
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67130.1__F0

<400>  8753

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Ser 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8754
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67185.1__F0

<400>  8754

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ala Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8755
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67163.1__F0

<400>  8755

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Arg Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8756
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67086.1__F0

<400>  8756

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ile 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8757
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67075.1__F0

<400>  8757

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Val Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8758
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66998.1__F0

<400>  8758

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asp Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8759
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66987.1__F0

<400>  8759

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8760
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66976.1__F0

<400>  8760

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8761
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66965.1__F0

<400>  8761

Met Glu Leu Leu Ile His Lys Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Met Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8762
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66921.1__F0

<400>  8762

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Ser Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8763
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66844.1__F0

<400>  8763

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Thr Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8764
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66833.1__F0

<400>  8764

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ala Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8765
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66624.1__F0

<400>  8765

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Lys Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asn Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8766
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66613.1__F0

<400>  8766

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Thr Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8767
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66591.1__F0

<400>  8767

Met Lys Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8768
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66569.1__F0

<400>  8768

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Ile Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8769
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66547.1__F0

<400>  8769

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8770
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66503.1__F0

<400>  8770

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8771
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66492.1__F0

<400>  8771

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Met Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Ser Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8772
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66481.1__F0

<400>  8772

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asn Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8773
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66448.1__F0

<400>  8773

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Asn 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Arg Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8774
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66415.1__F0

<400>  8774

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8775
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66393.1__F0

<400>  8775

Met Glu Leu Leu Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Met Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8776
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66360.1__F0

<400>  8776

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8777
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39553.1__F0

<400>  8777

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Val Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8778
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39469.1__F0

<400>  8778

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8779
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70144.1__F0

<400>  8779

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Ser Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8780
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70166.1__F0

<400>  8780

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8781
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70155.1__F0

<400>  8781

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Ile Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8782
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70133.1__F0

<400>  8782

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Thr Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8783
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70067.1__F0

<400>  8783

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Ile Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8784
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69946.1__F0

<400>  8784

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8785
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69913.1__F0

<400>  8785

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8786
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69880.1__F0

<400>  8786

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Pro Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8787
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69847.1__F0

<400>  8787

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8788
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69869.1__F0

<400>  8788

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8789
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJO16077.1__F0

<400>  8789

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Ile Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8790
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJO16055.1__F0

<400>  8790

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys His Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8791
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKE31881.1__F0

<400>  8791

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8792
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKE31882.1__F0

<400>  8792

Met Glu Leu Leu Val His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8793
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44835.1__F0

<400>  8793

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Asn Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8794
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44790.1__F0

<400>  8794

Met Glu Leu Ser Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8795
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44737.1__F0

<400>  8795

Met Glu Leu Pro Ile Leu Lys Thr Asn Val Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Tyr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8796
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44716.1__F0

<400>  8796

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Val Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8797
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44725.1__F0

<400>  8797

Met Glu Leu Pro Ile Leu Lys Thr Asn Val Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Tyr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8798
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44643.1__F0

<400>  8798

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8799
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44628.1__F0

<400>  8799

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8800
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44624.1__F0

<400>  8800

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8801
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44613.1__F0

<400>  8801

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Ser Asn Val Ser 
        115                 120                 125             


Thr Ile Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8802
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44566.1__F0

<400>  8802

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8803
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44555.1__F0

<400>  8803

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Asn Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8804
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44526.1__F0

<400>  8804

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Arg Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8805
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44517.1__F0

<400>  8805

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8806
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHB33455.1__F0

<400>  8806

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Thr Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8807
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45882.1__F0

<400>  8807

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Ser 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8808
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45849.1__F0

<400>  8808

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8809
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83913.1__F0

<400>  8809

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Ile Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8810
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28715.1__F0

<400>  8810

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8811
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83902.1__F0

<400>  8811

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Ile Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Met Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8812
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83837.1__F0

<400>  8812

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8813
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83826.1__F0

<400>  8813

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asn Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8814
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83705.1__F0

<400>  8814

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Asn Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8815
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83630.1__F0

<400>  8815

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Arg Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8816
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39505.1__F0

<400>  8816

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8817
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY70242.1__F0

<400>  8817

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8818
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY70198.1__F0

<400>  8818

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Glu Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8819
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AII30203.1__F0

<400>  8819

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Arg Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8820
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21441.1__F0

<400>  8820

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Ser Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8821
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21463.1__F0

<400>  8821

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Val Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8822
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21397.1__F0

<400>  8822

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Thr Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8823
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21320.1__F0

<400>  8823

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Glu Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8824
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21298.1__F0

<400>  8824

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8825
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21287.1__F0

<400>  8825

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8826
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21276.1__F0

<400>  8826

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8827
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21254.1__F0

<400>  8827

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Ser Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8828
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21199.1__F0

<400>  8828

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Ile Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8829
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21176.1__F0

<400>  8829

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8830
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57537.1__F0

<400>  8830

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Ser Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8831
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57471.1__F0

<400>  8831

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Ser Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8832
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57427.1__F0

<400>  8832

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Lys 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8833
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57042.1__F0

<400>  8833

Met Glu Leu Leu Ile His Arg Ser Ser Val Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8834
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95981.1__F0

<400>  8834

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Ile Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asn Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8835
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95893.1__F0

<400>  8835

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Val Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8836
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95871.1__F0

<400>  8836

Met Glu Leu Leu Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Ile Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8837
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95816.1__F0

<400>  8837

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ile Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Ser Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8838
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95772.1__F0

<400>  8838

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Thr Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8839
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95684.1__F0

<400>  8839

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Ile Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8840
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95629.1__F0

<400>  8840

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Thr Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8841
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95673.1__F0

<400>  8841

Met Glu Ser Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8842
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95596.1__F0

<400>  8842

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Val Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8843
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95585.1__F0

<400>  8843

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Ser Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asp Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8844
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95552.1__F0

<400>  8844

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8845
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57570.1__F0

<400>  8845

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Lys Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8846
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57152.1__F0

<400>  8846

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Tyr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8847
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57064.1__F0

<400>  8847

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Gly Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Tyr Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8848
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57020.1__F0

<400>  8848

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Ile Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8849
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57009.1__F0

<400>  8849

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Ile 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8850
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX56987.1__F0

<400>  8850

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Ile Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8851
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV82100.1__F0

<400>  8851

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8852
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV82001.1__F0

<400>  8852

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8853
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81891.1__F0

<400>  8853

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8854
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81880.1__F0

<400>  8854

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8855
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81836.1__F0

<400>  8855

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Cys Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8856
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81682.1__F0

<400>  8856

Met Glu Leu Pro Val Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8857
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81649.1__F0

<400>  8857

Met Glu Leu Pro Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8858
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81484.1__F0

<400>  8858

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8859
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81462.1__F0

<400>  8859

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Arg Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8860
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81385.1__F0

<400>  8860

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8861
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81363.1__F0

<400>  8861

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Val Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8862
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81330.1__F0

<400>  8862

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Phe Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8863
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81253.1__F0

<400>  8863

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Asn Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8864
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81154.1__F0

<400>  8864

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8865
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81122.1__F0

<400>  8865

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Asn Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Lys Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8866
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81089.1__F0

<400>  8866

Met Gly Leu Leu Ile His Gly Ser Ser Ala Val Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8867
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81012.1__F0

<400>  8867

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Asn Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8868
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80957.1__F0

<400>  8868

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8869
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80880.1__F0

<400>  8869

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Ile Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8870
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80869.1__F0

<400>  8870

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Arg Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8871
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80836.1__F0

<400>  8871

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Ala Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8872
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80803.1__F0

<400>  8872

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asp Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8873
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39559.1__F0

<400>  8873

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Gln Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8874
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39562.1__F0

<400>  8874

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ser Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8875
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39556.1__F0

<400>  8875

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Met Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8876
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39550.1__F0

<400>  8876

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8877
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39547.1__F0

<400>  8877

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Leu Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8878
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39544.1__F0

<400>  8878

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Ile Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8879
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39541.1__F0

<400>  8879

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8880
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39529.1__F0

<400>  8880

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8881
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39526.1__F0

<400>  8881

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asn Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8882
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39523.1__F0

<400>  8882

Met Glu Leu Leu Ile His Arg Ser Ile Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Thr Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8883
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39514.1__F0

<400>  8883

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Val Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Tyr Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8884
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39502.1__F0

<400>  8884

Met Glu Leu Leu Val His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Asn Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Ala Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8885
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39499.1__F0

<400>  8885

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8886
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39496.1__F0

<400>  8886

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Ile Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Thr Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8887
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39493.1__F0

<400>  8887

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Gln Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8888
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39484.1__F0

<400>  8888

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Thr Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8889
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39490.1__F0

<400>  8889

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8890
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39487.1__F0

<400>  8890

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Val Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Met Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Ile Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Arg Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8891
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39475.1__F0

<400>  8891

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8892
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39466.1__F0

<400>  8892

Met Glu Leu Leu Ile Leu Lys Ala Asn Val Ile Ala Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8893
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39463.1__F0

<400>  8893

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Asn Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8894
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39454.1__F0

<400>  8894

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8895
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39442.1__F0

<400>  8895

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Ser Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8896
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39439.1__F0

<400>  8896

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Met Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8897
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39436.1__F0

<400>  8897

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8898
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39415.1__F0

<400>  8898

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8899
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39403.1__F0

<400>  8899

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Met Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8900
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39412.1__F0

<400>  8900

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8901
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39397.1__F0

<400>  8901

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Thr Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8902
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39391.1__F0

<400>  8902

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8903
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39385.1__F0

<400>  8903

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8904
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39379.1__F0

<400>  8904

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8905
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHL84194.1__F0

<400>  8905

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8906
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA84012.1__F0

<400>  8906

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8907
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHJ60043.1__F0

<400>  8907

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Thr Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8908
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BAO49770.1__F0

<400>  8908

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Gly Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Pro Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8909
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BAO49766.1__F0

<400>  8909

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Pro Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Gly Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8910
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BAO49767.1__F0

<400>  8910

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Cys Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8911
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA84034.1__F0

<400>  8911

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asp Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8912
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA84023.1__F0

<400>  8912

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8913
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83990.1__F0

<400>  8913

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8914
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83957.1__F0

<400>  8914

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8915
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83924.1__F0

<400>  8915

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Phe Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8916
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83891.1__F0

<400>  8916

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Ala Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8917
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83880.1__F0

<400>  8917

Met Asp Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8918
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83782.1__F0

<400>  8918

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8919
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83760.1__F0

<400>  8919

Met Glu Leu Pro Ile Ile Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Met Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Asn Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8920
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83694.1__F0

<400>  8920

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Asp Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8921
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGT75357.1__F0

<400>  8921

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Ile Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8922
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN92848.1__F0

<400>  8922

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Ile Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Leu Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8923
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28792.1__F0

<400>  8923

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Met Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8924
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28781.1__F0

<400>  8924

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8925
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28759.1__F0

<400>  8925

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8926
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28748.1__F0

<400>  8926

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8927
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28693.1__F0

<400>  8927

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Lys Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8928
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28638.1__F0

<400>  8928

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Gln Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8929
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28627.1__F0

<400>  8929

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Arg Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8930
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28539.1__F0

<400>  8930

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Ile Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8931
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28528.1__F0

<400>  8931

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Ser 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8932
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28462.1__F0

<400>  8932

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Met Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8933
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGL96787.1__F0

<400>  8933

Met Glu Val Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ala Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8934
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGL96786.1__F0

<400>  8934

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Thr Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8935
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGL96784.1__F0

<400>  8935

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Thr Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Arg Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8936
<211>  571
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54517.1__F0

<400>  8936

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Val Ile Ala Val Ser 
                565                 570     


<210>  8937
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(Memphis-37)__AIY60640.1__F0

<400>  8937

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8938
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABQ42594.1__F0

<400>  8938

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Val Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8939
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACO83297.1__F0

<400>  8939

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Arg Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Lys Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Tyr Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Ile Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8940
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACO83301.1__F0

<400>  8940

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Ile Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8941
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95775.1__F0

<400>  8941

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Glu 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8942
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95779.1__F0

<400>  8942

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Leu Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8943
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63597.1__F0

<400>  8943

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Ile Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8944
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63608.1__F0

<400>  8944

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Thr Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8945
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63630.1__F0

<400>  8945

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Arg Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys Asn Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Lys 
                565                 570                 


<210>  8946
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHE57683.1__F0

<400>  8946

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8947
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHE57894.1__F0

<400>  8947

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Ile Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8948
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80511.1__F0

<400>  8948

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Thr Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Lys Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Ser 
                565                 570                 


<210>  8949
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80560.1__F0

<400>  8949

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8950
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80660.1__F0

<400>  8950

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8951
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80670.1__F0

<400>  8951

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Ile Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8952
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80760.1__F0

<400>  8952

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Ile Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8953
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80800.1__F0

<400>  8953

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Ile Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8954
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80860.1__F0

<400>  8954

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Leu Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8955
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80990.1__F0

<400>  8955

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Leu Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8956
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81370.1__F0

<400>  8956

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ala Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8957
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX22013.1__F0

<400>  8957

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Ile Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8958
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA62675.1__F0

<400>  8958

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Phe Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8959
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA62685.1__F0

<400>  8959

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Phe Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8960
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63044.1__F0

<400>  8960

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Pro Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8961
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63234.1__F0

<400>  8961

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Phe Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8962
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63364.1__F0

<400>  8962

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Ile Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8963
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63604.1__F0

<400>  8963

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Val Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8964
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUH26189.1__F0

<400>  8964

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Arg Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8965
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__NP_044596.1__F0

<400>  8965

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Thr Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8966
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__1701388A__F0

<400>  8966

Met Glu Leu Pro Ile Leu Lys Thr Asn Thr Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8967
<211>  574
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__WP_079890144.1__F0

<400>  8967

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Ile Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Val Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg Ser Thr Pro Val Thr Leu Ser 
545                 550                 555                 560 


Lys Asp Gln Leu Ser Gly Ile Asn Asn Ile Ala Phe Ser Asn 
                565                 570                 


<210>  8968
<211>  568
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44801.1__F-del

<400>  8968

Met Ile Pro Gln Ala Arg Thr Lys Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys 
                565             


<210>  8969
<211>  568
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44759.1__F-del

<400>  8969

Met Ile Pro Gln Ala Arg Thr Lys Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Arg Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys 
                565             


<210>  8970
<211>  568
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44661.1__F-del

<400>  8970

Met Ile Pro Gln Ala Arg Thr Glu Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Glu Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys 
                565             


<210>  8971
<211>  568
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44602.1__F-del

<400>  8971

Met Ile Pro Gln Ala Arg Thr Glu Leu Asn Leu Gly Gln Ile Thr Met 
1               5                   10                  15      


Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala Ile 
            20                  25                  30          


Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe Tyr 
        35                  40                  45              


Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu Arg 
    50                  55                  60                  


Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile Lys 
65                  70                  75                  80  


Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys Gln 
                85                  90                  95      


Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu Met 
            100                 105                 110         


Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro Gln 
        115                 120                 125             


Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Ser Leu Asn Val Ser Ile 
    130                 135                 140                 


Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val Gly 
145                 150                 155                 160 


Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu Glu 
                165                 170                 175     


Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys Ala 
            180                 185                 190         


Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val Leu 
        195                 200                 205             


Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn Gln 
    210                 215                 220                 


Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln Gln 
225                 230                 235                 240 


Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn Ala 
                245                 250                 255     


Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu Leu 
            260                 265                 270         


Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys Leu 
        275                 280                 285             


Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile Met 
    290                 295                 300                 


Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro Ile 
305                 310                 315                 320 


Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro Leu 
                325                 330                 335     


Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg Thr 
            340                 345                 350         


Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe Pro 
        355                 360                 365             


Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp Thr 
    370                 375                 380                 


Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr Asp 
385                 390                 395                 400 


Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr Asp 
                405                 410                 415     


Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys Tyr 
            420                 425                 430         


Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile Lys 
        435                 440                 445             


Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp Thr 
    450                 455                 460                 


Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly Lys 
465                 470                 475                 480 


Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro Leu 
                485                 490                 495     


Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn Glu 
            500                 505                 510         


Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu Leu 
        515                 520                 525             


His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr Ala 
    530                 535                 540                 


Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile Gly 
545                 550                 555                 560 


Leu Leu Leu Tyr Cys Lys Ala Lys 
                565             


<210>  8972
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__2207424A__F-del

<400>  8972

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Ser 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8973
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38520.1__F-del

<400>  8973

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Leu Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8974
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38517.1__F-del

<400>  8974

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Thr Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Ser 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8975
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38519.1__F-del

<400>  8975

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Val Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Ile Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Thr Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Leu Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8976
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB38518.1__F-del

<400>  8976

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Thr Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Thr Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Ser 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Trp Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8977
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93587.1__F-del

<400>  8977

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Val Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8978
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93599.1__F-del

<400>  8978

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Val 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Thr Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8979
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93571.1__F-del

<400>  8979

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Phe Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Phe Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8980
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93568.1__F-del

<400>  8980

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Thr Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8981
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93589.1__F-del

<400>  8981

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Val Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8982
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93597.1__F-del

<400>  8982

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Val Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8983
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93563.1__F-del

<400>  8983

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Cys Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Leu Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8984
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93594.1__F-del

<400>  8984

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8985
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93601.1__F-del

<400>  8985

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Asn Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8986
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93562.1__F-del

<400>  8986

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Ser Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Gly Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Met Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8987
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93561.1__F-del

<400>  8987

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Gly Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8988
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93607.1__F-del

<400>  8988

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asn Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8989
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93588.1__F-del

<400>  8989

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8990
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93575.1__F-del

<400>  8990

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Val Lys 
545                 550             


<210>  8991
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93468.1__F-del

<400>  8991

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Pro Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Ile Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8992
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93467.1__F-del

<400>  8992

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Glu Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8993
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93590.1__F-del

<400>  8993

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8994
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93552.1__F-del

<400>  8994

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Leu 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8995
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93556.1__F-del

<400>  8995

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asn 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  8996
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93471.1__F-del

<400>  8996

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Arg Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8997
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93458.1__F-del

<400>  8997

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8998
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93494.1__F-del

<400>  8998

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Ile Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Ile Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  8999
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93470.1__F-del

<400>  8999

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Ser Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ala Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9000
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93489.1__F-del

<400>  9000

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Val Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9001
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93542.1__F-del

<400>  9001

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Ser Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9002
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93472.1__F-del

<400>  9002

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ser Ser Ser Gln Asn Ile Thr Glu Lys Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Lys Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu His Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Pro Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ile Lys Lys Arg Lys Arg Thr Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Gln Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9003
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93514.1__F-del

<400>  9003

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9004
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93485.1__F-del

<400>  9004

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Lys Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Asn Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9005
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93533.1__F-del

<400>  9005

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Ile His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9006
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93481.1__F-del

<400>  9006

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Thr Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Ile Gly Ala Ile Val Ser Trp 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Cys Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Ile Ser Cys Lys Ala Arg 
545                 550             


<210>  9007
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93546.1__F-del

<400>  9007

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9008
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93512.1__F-del

<400>  9008

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Leu Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9009
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93554.1__F-del

<400>  9009

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Met Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9010
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93551.1__F-del

<400>  9010

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Pro Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9011
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93547.1__F-del

<400>  9011

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9012
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93558.1__F-del

<400>  9012

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Tyr Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Ile Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9013
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93461.1__F-del

<400>  9013

Met Glu Ser Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9014
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93500.1__F-del

<400>  9014

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Ile Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9015
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93426.1__F-del

<400>  9015

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Tyr Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9016
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93398.1__F-del

<400>  9016

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9017
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93401.1__F-del

<400>  9017

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Tyr Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9018
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93361.1__F-del

<400>  9018

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Ala Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9019
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93408.1__F-del

<400>  9019

Met Glu Leu Pro Ile Ser Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asn Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9020
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93443.1__F-del

<400>  9020

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9021
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93429.1__F-del

<400>  9021

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9022
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93359.1__F-del

<400>  9022

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9023
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93365.1__F-del

<400>  9023

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Val Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9024
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93366.1__F-del

<400>  9024

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Ile Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9025
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93402.1__F-del

<400>  9025

Met Glu Leu Pro Ile Leu Lys Thr Asn Thr Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ile Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Asn Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9026
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93377.1__F-del

<400>  9026

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9027
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93412.1__F-del

<400>  9027

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ile Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Ser Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asn Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9028
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93391.1__F-del

<400>  9028

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9029
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93457.1__F-del

<400>  9029

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Ile Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9030
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93372.1__F-del

<400>  9030

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asn Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9031
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93455.1__F-del

<400>  9031

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9032
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93364.1__F-del

<400>  9032

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Ile Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9033
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93378.1__F-del

<400>  9033

Met Gln Leu Pro Ile Leu Lys Ile Tyr Ala Ile Thr Ser Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Tyr Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9034
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93393.1__F-del

<400>  9034

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Lys Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9035
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93362.1__F-del

<400>  9035

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9036
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93585.1__F-del

<400>  9036

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Val 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9037
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28504.1__F-del

<400>  9037

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9038
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AVQ93404.1__F-del

<400>  9038

Met Glu Leu Pro Ile Ser Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9039
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS49123.1__F-del

<400>  9039

Met Glu Leu Pro Ile Leu Lys Thr Asn Thr Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9040
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48496.1__F-del

<400>  9040

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9041
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78271.1__F-del

<400>  9041

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9042
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57174.1__F-del

<400>  9042

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Lys Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9043
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81390.1__F-del

<400>  9043

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9044
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81506.1__F-del

<400>  9044

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9045
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60128.1__F-del

<400>  9045

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9046
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60129.1__F-del

<400>  9046

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9047
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63389.1__F-del

<400>  9047

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9048
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB66328.1__F-del

<400>  9048

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Arg Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Ser Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Thr Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9049
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80034.1__F-del

<400>  9049

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Ser Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9050
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91253.1__F-del

<400>  9050

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9051
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P03420.1__F-del

<400>  9051

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Pro Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Ile Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Met Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9052
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIO08046.1__F-del

<400>  9052

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9053
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__NP_056863.1__F-del

<400>  9053

Met Glu Leu Leu Ile His Arg Leu Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Asn Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9054
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60234.1__F-del

<400>  9054

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9055
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60231.1__F-del

<400>  9055

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Arg Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9056
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60232.1__F-del

<400>  9056

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9057
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60222.1__F-del

<400>  9057

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Ile Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ile Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9058
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60219.1__F-del

<400>  9058

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9059
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60215.1__F-del

<400>  9059

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9060
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60214.1__F-del

<400>  9060

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9061
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60212.1__F-del

<400>  9061

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9062
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60208.1__F-del

<400>  9062

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9063
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60202.1__F-del

<400>  9063

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9064
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60220.1__F-del

<400>  9064

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Ile Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9065
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60213.1__F-del

<400>  9065

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9066
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60190.1__F-del

<400>  9066

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Phe 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9067
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60187.1__F-del

<400>  9067

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ser Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9068
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60201.1__F-del

<400>  9068

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9069
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60173.1__F-del

<400>  9069

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Ser Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9070
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60169.1__F-del

<400>  9070

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ser Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9071
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60162.1__F-del

<400>  9071

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Phe 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9072
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60156.1__F-del

<400>  9072

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ile Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9073
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60151.1__F-del

<400>  9073

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Leu Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9074
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60150.1__F-del

<400>  9074

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9075
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60148.1__F-del

<400>  9075

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Leu Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9076
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60127.1__F-del

<400>  9076

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9077
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60137.1__F-del

<400>  9077

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Lys Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9078
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60135.1__F-del

<400>  9078

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9079
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46420.1__F-del

<400>  9079

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Ile Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Phe Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9080
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60200.1__F-del

<400>  9080

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Val Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9081
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46419.1__F-del

<400>  9081

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Ile Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9082
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46417.1__F-del

<400>  9082

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Thr Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9083
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46413.1__F-del

<400>  9083

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9084
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46414.1__F-del

<400>  9084

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9085
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46410.1__F-del

<400>  9085

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Thr Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Ile Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9086
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46403.1__F-del

<400>  9086

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9087
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46409.1__F-del

<400>  9087

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Thr Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9088
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99061.1__F-del

<400>  9088

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9089
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95400.1__F-del

<400>  9089

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Asn Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9090
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFV46401.1__F-del

<400>  9090

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Ile Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9091
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99064.1__F-del

<400>  9091

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9092
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95376.1__F-del

<400>  9092

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asn Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9093
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX60138.1__F-del

<400>  9093

Met Glu Leu Pro Ile Leu Lys Thr Asn Ser Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9094
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99060.1__F-del

<400>  9094

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9095
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95365.1__F-del

<400>  9095

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Tyr Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9096
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55563.1__F-del

<400>  9096

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9097
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55530.1__F-del

<400>  9097

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Ser Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Ile Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9098
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55442.1__F-del

<400>  9098

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9099
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55420.1__F-del

<400>  9099

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Val Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9100
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55552.1__F-del

<400>  9100

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9101
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55365.1__F-del

<400>  9101

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Ile His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9102
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFP99059.1__F-del

<400>  9102

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9103
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55354.1__F-del

<400>  9103

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9104
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55343.1__F-del

<400>  9104

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Ala Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9105
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55387.1__F-del

<400>  9105

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ile Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9106
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55299.1__F-del

<400>  9106

Met Asp Leu Pro Ile Leu Lys Thr Lys Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Asn Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9107
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55288.1__F-del

<400>  9107

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9108
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55266.1__F-del

<400>  9108

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9109
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55277.1__F-del

<400>  9109

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9110
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55255.1__F-del

<400>  9110

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Phe Lys Ala Arg 
545                 550             


<210>  9111
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55222.1__F-del

<400>  9111

Met Glu Leu Pro Ile Leu Lys Thr Asn Val Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9112
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55211.1__F-del

<400>  9112

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9113
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFI25262.1__F-del

<400>  9113

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ser Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9114
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34266.1__F-del

<400>  9114

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9115
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55332.1__F-del

<400>  9115

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9116
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34264.1__F-del

<400>  9116

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Gly Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9117
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34262.1__F-del

<400>  9117

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr His Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9118
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34265.1__F-del

<400>  9118

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Ser 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Ala Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9119
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34261.1__F-del

<400>  9119

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Gly Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9120
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34260.1__F-del

<400>  9120

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9121
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFD34259.1__F-del

<400>  9121

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Met Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9122
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63641.1__F-del

<400>  9122

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Phe Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9123
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63487.1__F-del

<400>  9123

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9124
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63520.1__F-del

<400>  9124

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9125
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__4CCF_A__F-del

<400>  9125

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Val Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9126
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63334.1__F-del

<400>  9126

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9127
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45949.1__F-del

<400>  9127

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9128
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45939.1__F-del

<400>  9128

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Phe Ile Asp Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9129
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63312.1__F-del

<400>  9129

Met Glu Leu Pro Val Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9130
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63586.1__F-del

<400>  9130

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9131
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45919.1__F-del

<400>  9131

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9132
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45909.1__F-del

<400>  9132

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9133
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45889.1__F-del

<400>  9133

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9134
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45879.1__F-del

<400>  9134

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9135
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45869.1__F-del

<400>  9135

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9136
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45929.1__F-del

<400>  9136

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9137
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45850.1__F-del

<400>  9137

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9138
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45859.1__F-del

<400>  9138

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9139
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63444.1__F-del

<400>  9139

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9140
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO23054.1__F-del

<400>  9140

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Thr Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9141
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO23052.1__F-del

<400>  9141

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Ser Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9142
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO23051.1__F-del

<400>  9142

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9143
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEC32087.1__F-del

<400>  9143

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9144
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95785.1__F-del

<400>  9144

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Glu 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9145
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEC32085.1__F-del

<400>  9145

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Thr Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Gly Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Lys Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9146
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95784.1__F-del

<400>  9146

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Gln 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9147
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95783.1__F-del

<400>  9147

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Thr 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9148
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95782.1__F-del

<400>  9148

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Met 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9149
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95781.1__F-del

<400>  9149

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Asn 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9150
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95779.1__F-del

<400>  9150

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Leu Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9151
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95778.1__F-del

<400>  9151

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Ser Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Phe Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9152
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95775.1__F-del

<400>  9152

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Glu 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9153
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACY68435.1__F-del

<400>  9153

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Thr Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9154
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACO83302.1__F-del

<400>  9154

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9155
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABI35685.1__F-del

<400>  9155

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Ala 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9156
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFI25251.1__F-del

<400>  9156

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Met Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9157
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAX23994.1__F-del

<400>  9157

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Asn 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Thr Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9158
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97026.1__F-del

<400>  9158

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Gly Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9159
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAR14266.1__F-del

<400>  9159

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Thr Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Ser Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9160
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97027.1__F-del

<400>  9160

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Arg Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9161
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97030.1__F-del

<400>  9161

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ala 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9162
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97028.1__F-del

<400>  9162

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Glu Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9163
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAC57027.1__F-del

<400>  9163

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9164
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97029.1__F-del

<400>  9164

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Leu Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9165
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAQ97031.1__F-del

<400>  9165

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9166
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM68160.1__F-del

<400>  9166

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9167
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM44851.1__F-del

<400>  9167

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9168
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P11209.2__F-del

<400>  9168

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asp Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9169
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P13843.1__F-del

<400>  9169

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Val Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Arg Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Met Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9170
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAO72325.1__F-del

<400>  9170

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Ala Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu His Leu Lys Asn Tyr Ile Asp Lys Gln Phe Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Met Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9171
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM68157.1__F-del

<400>  9171

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9172
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__CAA26143.1__F-del

<400>  9172

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Phe Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9173
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__1512372A__F-del

<400>  9173

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asp 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Ala Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9174
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB86664.1__F-del

<400>  9174

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9175
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAO72324.1__F-del

<400>  9175

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Phe Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9176
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAB82446.1__F-del

<400>  9176

Met Glu Leu Leu Ile His Arg Leu Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Gly Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Asn Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9177
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAO72323.1__F-del

<400>  9177

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Ala Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Met Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9178
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAM68154.1__F-del

<400>  9178

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Ile Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Cys Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9179
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAA47410.1__F-del

<400>  9179

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9180
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P12568.1__F-del

<400>  9180

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Thr Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Ala Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9181
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB07894.1__F-del

<400>  9181

Met Glu Leu Leu Ile His Arg Leu Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Asn Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Tyr Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9182
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39517.1__F-del

<400>  9182

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9183
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54612.1__F-del

<400>  9183

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Ile Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9184
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54636.1__F-del

<400>  9184

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Leu Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9185
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54627.1__F-del

<400>  9185

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Gly Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Ser Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9186
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54621.1__F-del

<400>  9186

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Thr Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9187
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54570.1__F-del

<400>  9187

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ser Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9188
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54579.1__F-del

<400>  9188

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9189
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54595.1__F-del

<400>  9189

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9190
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54555.1__F-del

<400>  9190

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Leu Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9191
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54552.1__F-del

<400>  9191

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ala Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9192
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54564.1__F-del

<400>  9192

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Ile Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9193
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54581.1__F-del

<400>  9193

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Ser Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9194
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54571.1__F-del

<400>  9194

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Leu Met Asn Tyr Thr Leu Lys Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9195
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54553.1__F-del

<400>  9195

Met Glu Leu Leu Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Ile Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9196
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54565.1__F-del

<400>  9196

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Met Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Ala Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9197
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54245.1__F-del

<400>  9197

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Gln 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Ile Gln Pro 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9198
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54243.1__F-del

<400>  9198

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Ser Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9199
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54238.1__F-del

<400>  9199

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Lys Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9200
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54242.1__F-del

<400>  9200

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Ile Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9201
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54239.1__F-del

<400>  9201

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Tyr Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9202
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54235.1__F-del

<400>  9202

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Val Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asp Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9203
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54234.1__F-del

<400>  9203

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Asp Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9204
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54236.1__F-del

<400>  9204

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9205
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54244.1__F-del

<400>  9205

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Val Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Asp Asn Ser Arg Ala Arg Lys Glu Gln Pro 
            100                 105                 110         


Arg Phe Ile Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Met His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9206
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54186.1__F-del

<400>  9206

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Arg Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9207
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54178.1__F-del

<400>  9207

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asp Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9208
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54202.1__F-del

<400>  9208

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu His Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9209
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54151.1__F-del

<400>  9209

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Val Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9210
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54142.1__F-del

<400>  9210

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Phe Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9211
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54134.1__F-del

<400>  9211

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9212
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54170.1__F-del

<400>  9212

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9213
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54210.1__F-del

<400>  9213

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Val Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9214
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54169.1__F-del

<400>  9214

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9215
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54213.1__F-del

<400>  9215

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9216
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54203.1__F-del

<400>  9216

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9217
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54160.1__F-del

<400>  9217

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Ser Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9218
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54163.1__F-del

<400>  9218

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Val Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9219
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54215.1__F-del

<400>  9219

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9220
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54156.1__F-del

<400>  9220

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Val Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9221
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54179.1__F-del

<400>  9221

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Gly Arg 
545                 550             


<210>  9222
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54150.1__F-del

<400>  9222

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9223
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54207.1__F-del

<400>  9223

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asp Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9224
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54194.1__F-del

<400>  9224

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Tyr Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9225
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54149.1__F-del

<400>  9225

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn His Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9226
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54138.1__F-del

<400>  9226

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Ile Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9227
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54199.1__F-del

<400>  9227

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Thr Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Glu Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9228
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54220.1__F-del

<400>  9228

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Val Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9229
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54181.1__F-del

<400>  9229

Met Glu Leu Pro Ile Ile Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9230
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54132.1__F-del

<400>  9230

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Ile Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9231
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54146.1__F-del

<400>  9231

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Ile Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9232
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54122.1__F-del

<400>  9232

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Ile Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9233
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBC54124.1__F-del

<400>  9233

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Ser Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9234
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35202.1__F-del

<400>  9234

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9235
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35201.1__F-del

<400>  9235

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Ser Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9236
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35192.1__F-del

<400>  9236

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Tyr Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9237
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35193.1__F-del

<400>  9237

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Arg Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9238
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35199.1__F-del

<400>  9238

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Leu Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9239
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35184.1__F-del

<400>  9239

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9240
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35126.1__F-del

<400>  9240

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9241
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35133.1__F-del

<400>  9241

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ser Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9242
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35130.1__F-del

<400>  9242

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9243
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35160.1__F-del

<400>  9243

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Thr Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9244
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35162.1__F-del

<400>  9244

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Thr Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Thr Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9245
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35181.1__F-del

<400>  9245

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Thr Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Ile Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9246
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35165.1__F-del

<400>  9246

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Phe Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9247
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35121.1__F-del

<400>  9247

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9248
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35138.1__F-del

<400>  9248

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9249
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35176.1__F-del

<400>  9249

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asp Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9250
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35142.1__F-del

<400>  9250

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9251
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35136.1__F-del

<400>  9251

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9252
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35153.1__F-del

<400>  9252

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Thr 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9253
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35115.1__F-del

<400>  9253

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9254
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35150.1__F-del

<400>  9254

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9255
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35097.1__F-del

<400>  9255

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9256
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35109.1__F-del

<400>  9256

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Met Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9257
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35094.1__F-del

<400>  9257

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Leu Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9258
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35183.1__F-del

<400>  9258

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Thr Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Val Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9259
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35104.1__F-del

<400>  9259

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Met Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9260
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35099.1__F-del

<400>  9260

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ser Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9261
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBB35188.1__F-del

<400>  9261

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Tyr Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ser Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9262
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45871.1__F-del

<400>  9262

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9263
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASV65838.1__F-del

<400>  9263

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9264
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39373.1__F-del

<400>  9264

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Ser Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9265
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AII22107.1__F-del

<400>  9265

Met Glu Leu Leu Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9266
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39400.1__F-del

<400>  9266

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9267
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39457.1__F-del

<400>  9267

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9268
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29240.1__F-del

<400>  9268

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Ile Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9269
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29251.1__F-del

<400>  9269

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Val Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9270
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29189.1__F-del

<400>  9270

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asp Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9271
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29207.1__F-del

<400>  9271

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Glu Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9272
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUH15164.1__F-del

<400>  9272

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Glu Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9273
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV81343.1__F-del

<400>  9273

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9274
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68654.1__F-del

<400>  9274

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9275
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68577.1__F-del

<400>  9275

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Val Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Asp Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9276
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68566.1__F-del

<400>  9276

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asn Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9277
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68555.1__F-del

<400>  9277

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9278
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68478.1__F-del

<400>  9278

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Ala Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Val Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9279
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68445.1__F-del

<400>  9279

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Ser Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9280
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68500.1__F-del

<400>  9280

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9281
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68522.1__F-del

<400>  9281

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9282
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68291.1__F-del

<400>  9282

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Thr Ile Val Ile Thr Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9283
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68149.1__F-del

<400>  9283

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9284
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68094.1__F-del

<400>  9284

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ala Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Pro His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9285
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67097.1__F-del

<400>  9285

Met Glu Leu Leu Ile His Arg Ser Ser Ala Val Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Arg Ala Lys 
545                 550             


<210>  9286
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66866.1__F-del

<400>  9286

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9287
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66580.1__F-del

<400>  9287

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9288
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95750.1__F-del

<400>  9288

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Ile Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9289
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95541.1__F-del

<400>  9289

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9290
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95519.1__F-del

<400>  9290

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9291
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21419.1__F-del

<400>  9291

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ala Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9292
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21331.1__F-del

<400>  9292

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9293
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21165.1__F-del

<400>  9293

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Asp Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9294
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21143.1__F-del

<400>  9294

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9295
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21132.1__F-del

<400>  9295

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9296
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39478.1__F-del

<400>  9296

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9297
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV93506.1__F-del

<400>  9297

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ala Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Met Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9298
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV93509.1__F-del

<400>  9298

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ile Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9299
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95717.1__F-del

<400>  9299

Met Glu Leu Pro Thr Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Val Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9300
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV81354.1__F-del

<400>  9300

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9301
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28317.1__F-del

<400>  9301

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Gly Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Lys Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9302
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBA57901.1__F-del

<400>  9302

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Arg Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Met Val Asn 
        195                 200                 205             


Arg Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9303
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASZ70099.1__F-del

<400>  9303

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Asn Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9304
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28361.1__F-del

<400>  9304

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Val Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9305
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AQX36844.1__F-del

<400>  9305

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Ala Gln Ser Asn Arg Val Phe Asn Asn 
        355                 360                 365             


Thr Ile Thr Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9306
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASK05520.1__F-del

<400>  9306

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9307
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28427.1__F-del

<400>  9307

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Glu Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9308
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28297.1__F-del

<400>  9308

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ser Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9309
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28328.1__F-del

<400>  9309

Met Asp Ser Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9310
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARQ15966.1__F-del

<400>  9310

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Tyr Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9311
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARN61507.1__F-del

<400>  9311

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Gly Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asp 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Leu Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9312
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARA15413.1__F-del

<400>  9312

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9313
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39394.1__F-del

<400>  9313

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9314
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78845.1__F-del

<400>  9314

Met Glu Leu Leu Ile His Arg Pro Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9315
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78867.1__F-del

<400>  9315

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Arg Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9316
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78900.1__F-del

<400>  9316

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Cys Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9317
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78878.1__F-del

<400>  9317

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Gln Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9318
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78779.1__F-del

<400>  9318

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9319
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78702.1__F-del

<400>  9319

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Ser Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Leu Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9320
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78713.1__F-del

<400>  9320

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Lys Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9321
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78680.1__F-del

<400>  9321

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9322
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78658.1__F-del

<400>  9322

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Trp Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asp Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9323
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78647.1__F-del

<400>  9323

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Asn Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9324
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78636.1__F-del

<400>  9324

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9325
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48870.1__F-del

<400>  9325

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Ser Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9326
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78614.1__F-del

<400>  9326

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu Leu Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9327
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78905.1__F-del

<400>  9327

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9328
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77402.1__F-del

<400>  9328

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9329
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOZ15479.1__F-del

<400>  9329

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Ser Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9330
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28484.1__F-del

<400>  9330

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9331
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57240.1__F-del

<400>  9331

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Gly Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Tyr Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9332
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57031.1__F-del

<400>  9332

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Ile Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9333
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48980.1__F-del

<400>  9333

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Ile Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9334
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48848.1__F-del

<400>  9334

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Tyr Lys Ala Lys 
545                 550             


<210>  9335
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48815.1__F-del

<400>  9335

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9336
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48738.1__F-del

<400>  9336

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Asn Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Leu Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9337
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS49068.1__F-del

<400>  9337

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Ile 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9338
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48727.1__F-del

<400>  9338

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Ile Tyr Cys Lys Ala Arg 
545                 550             


<210>  9339
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48716.1__F-del

<400>  9339

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ser Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9340
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48683.1__F-del

<400>  9340

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Thr 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9341
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48551.1__F-del

<400>  9341

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9342
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48485.1__F-del

<400>  9342

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu His Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Glu Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9343
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48518.1__F-del

<400>  9343

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Ile Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9344
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48441.1__F-del

<400>  9344

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Gly Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9345
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48397.1__F-del

<400>  9345

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Asp Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9346
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48375.1__F-del

<400>  9346

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Ile Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9347
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48353.1__F-del

<400>  9347

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9348
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48287.1__F-del

<400>  9348

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ile 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9349
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48320.1__F-del

<400>  9349

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Ile Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9350
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48265.1__F-del

<400>  9350

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9351
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48254.1__F-del

<400>  9351

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9352
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48221.1__F-del

<400>  9352

Met Glu Leu Leu Ile Arg Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile His Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9353
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79638.1__F-del

<400>  9353

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9354
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ALC74025.1__F-del

<400>  9354

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9355
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81286.1__F-del

<400>  9355

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9356
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40516.1__F-del

<400>  9356

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ala Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9357
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40125.1__F-del

<400>  9357

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Val Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Ser Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9358
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40104.1__F-del

<400>  9358

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ile Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9359
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD40082.1__F-del

<400>  9359

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9360
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOD39908.1__F-del

<400>  9360

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ile Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9361
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44826.1__F-del

<400>  9361

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Pro Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Gly Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ile Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9362
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44506.1__F-del

<400>  9362

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Ser Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9363
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44535.1__F-del

<400>  9363

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9364
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80463.1__F-del

<400>  9364

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asp Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9365
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80408.1__F-del

<400>  9365

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Lys Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9366
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80397.1__F-del

<400>  9366

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Asp Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9367
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80386.1__F-del

<400>  9367

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9368
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80331.1__F-del

<400>  9368

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Ile Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9369
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80320.1__F-del

<400>  9369

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Tyr Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ile 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9370
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80364.1__F-del

<400>  9370

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9371
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80276.1__F-del

<400>  9371

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Val Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9372
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80221.1__F-del

<400>  9372

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9373
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80188.1__F-del

<400>  9373

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9374
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80144.1__F-del

<400>  9374

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Ile Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9375
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80133.1__F-del

<400>  9375

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Arg Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9376
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80111.1__F-del

<400>  9376

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9377
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80122.1__F-del

<400>  9377

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Ile Asn Leu Asn Ile Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9378
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80056.1__F-del

<400>  9378

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Phe Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9379
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80012.1__F-del

<400>  9379

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Tyr Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9380
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80067.1__F-del

<400>  9380

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Gly Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Gly Lys Arg Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9381
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79979.1__F-del

<400>  9381

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9382
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79935.1__F-del

<400>  9382

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ile Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9383
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79990.1__F-del

<400>  9383

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Val Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9384
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79902.1__F-del

<400>  9384

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Asn Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9385
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79759.1__F-del

<400>  9385

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Ala Thr Val Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Lys Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9386
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79715.1__F-del

<400>  9386

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Val Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9387
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ79671.1__F-del

<400>  9387

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9388
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79718.1__F-del

<400>  9388

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Phe Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Ile Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9389
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79586.1__F-del

<400>  9389

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Ser Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9390
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79553.1__F-del

<400>  9390

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Ile Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9391
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79542.1__F-del

<400>  9391

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Ser Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9392
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79476.1__F-del

<400>  9392

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Ser Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9393
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79388.1__F-del

<400>  9393

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Val Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Val Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9394
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79201.1__F-del

<400>  9394

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Ile Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9395
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79190.1__F-del

<400>  9395

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Phe 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9396
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79157.1__F-del

<400>  9396

Met Glu Leu Leu Ile Arg Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9397
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79124.1__F-del

<400>  9397

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9398
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79091.1__F-del

<400>  9398

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys His Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9399
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79047.1__F-del

<400>  9399

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9400
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79014.1__F-del

<400>  9400

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ala Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9401
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79003.1__F-del

<400>  9401

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9402
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78872.1__F-del

<400>  9402

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9403
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78832.1__F-del

<400>  9403

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9404
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78689.1__F-del

<400>  9404

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Ile Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9405
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78645.1__F-del

<400>  9405

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Ile Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9406
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78513.1__F-del

<400>  9406

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ser Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9407
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78480.1__F-del

<400>  9407

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Ile Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9408
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78447.1__F-del

<400>  9408

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Lys Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9409
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78392.1__F-del

<400>  9409

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Val Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Thr Lys 
545                 550             


<210>  9410
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78194.1__F-del

<400>  9410

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Asn Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9411
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78084.1__F-del

<400>  9411

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Thr Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9412
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78051.1__F-del

<400>  9412

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asp Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9413
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77963.1__F-del

<400>  9413

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Asp Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9414
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77908.1__F-del

<400>  9414

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Ser Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9415
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77776.1__F-del

<400>  9415

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Arg Ala Lys 
545                 550             


<210>  9416
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77710.1__F-del

<400>  9416

Met Glu Leu Leu Ile Arg Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Arg Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Arg Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9417
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77424.1__F-del

<400>  9417

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Lys Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9418
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91385.1__F-del

<400>  9418

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Ala Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9419
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91264.1__F-del

<400>  9419

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Ala Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Ser Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9420
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91242.1__F-del

<400>  9420

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Thr Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ala Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9421
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57504.1__F-del

<400>  9421

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Asn Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9422
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__CUS01881.1__F-del

<400>  9422

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Thr Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9423
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__CUS01870.1__F-del

<400>  9423

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asn Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9424
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67350.1__F-del

<400>  9424

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9425
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67251.1__F-del

<400>  9425

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Cys Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9426
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67262.1__F-del

<400>  9426

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Val Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9427
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67229.1__F-del

<400>  9427

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9428
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67196.1__F-del

<400>  9428

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Glu Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9429
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67130.1__F-del

<400>  9429

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Ser 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9430
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67185.1__F-del

<400>  9430

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Ala Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9431
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67163.1__F-del

<400>  9431

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Arg Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9432
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67086.1__F-del

<400>  9432

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Ile 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9433
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67075.1__F-del

<400>  9433

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Val Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9434
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66998.1__F-del

<400>  9434

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asp Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9435
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66987.1__F-del

<400>  9435

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9436
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66976.1__F-del

<400>  9436

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9437
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66965.1__F-del

<400>  9437

Met Glu Leu Leu Ile His Lys Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Met Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9438
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66921.1__F-del

<400>  9438

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Ser Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9439
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66844.1__F-del

<400>  9439

Met Glu Leu Leu Ile Tyr Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Thr Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9440
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66833.1__F-del

<400>  9440

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ala Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9441
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66624.1__F-del

<400>  9441

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Lys Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asn Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9442
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66613.1__F-del

<400>  9442

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Thr Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9443
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66591.1__F-del

<400>  9443

Met Lys Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9444
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66569.1__F-del

<400>  9444

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Ile Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9445
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66547.1__F-del

<400>  9445

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9446
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66503.1__F-del

<400>  9446

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9447
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66492.1__F-del

<400>  9447

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Met Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9448
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66481.1__F-del

<400>  9448

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asn Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9449
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66448.1__F-del

<400>  9449

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Asn 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Arg Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9450
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66415.1__F-del

<400>  9450

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9451
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66393.1__F-del

<400>  9451

Met Glu Leu Leu Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Met Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9452
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66360.1__F-del

<400>  9452

Met Glu Leu Pro Ile Phe Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9453
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39553.1__F-del

<400>  9453

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Val Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9454
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39469.1__F-del

<400>  9454

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9455
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70144.1__F-del

<400>  9455

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Ser Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9456
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70166.1__F-del

<400>  9456

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9457
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70155.1__F-del

<400>  9457

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Ile Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9458
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70133.1__F-del

<400>  9458

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Thr Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9459
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70067.1__F-del

<400>  9459

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9460
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69946.1__F-del

<400>  9460

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9461
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69913.1__F-del

<400>  9461

Met Glu Leu Pro Ile Leu Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9462
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69880.1__F-del

<400>  9462

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Pro Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9463
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69847.1__F-del

<400>  9463

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9464
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69869.1__F-del

<400>  9464

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9465
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJO16077.1__F-del

<400>  9465

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Ile Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Gln Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9466
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJO16055.1__F-del

<400>  9466

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys His Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9467
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKE31881.1__F-del

<400>  9467

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9468
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKE31882.1__F-del

<400>  9468

Met Glu Leu Leu Val His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9469
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKE31878.1__F-del

<400>  9469

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Asn Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9470
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44835.1__F-del

<400>  9470

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Asn Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9471
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44790.1__F-del

<400>  9471

Met Glu Leu Ser Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9472
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44737.1__F-del

<400>  9472

Met Glu Leu Pro Ile Leu Lys Thr Asn Val Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Tyr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9473
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44716.1__F-del

<400>  9473

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Val Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9474
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44725.1__F-del

<400>  9474

Met Glu Leu Pro Ile Leu Lys Thr Asn Val Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Tyr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9475
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44643.1__F-del

<400>  9475

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9476
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44628.1__F-del

<400>  9476

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9477
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44624.1__F-del

<400>  9477

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9478
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44613.1__F-del

<400>  9478

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Ser Asn Val Ser 
        115                 120                 125             


Thr Ile Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9479
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44566.1__F-del

<400>  9479

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9480
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44555.1__F-del

<400>  9480

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Asn Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ile Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9481
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44526.1__F-del

<400>  9481

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Arg Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9482
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44517.1__F-del

<400>  9482

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9483
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45882.1__F-del

<400>  9483

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Ser 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9484
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45849.1__F-del

<400>  9484

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9485
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83913.1__F-del

<400>  9485

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Ile Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9486
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28715.1__F-del

<400>  9486

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9487
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83902.1__F-del

<400>  9487

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Ile Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Met Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9488
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83837.1__F-del

<400>  9488

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Asn Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9489
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83826.1__F-del

<400>  9489

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asn Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9490
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83705.1__F-del

<400>  9490

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Asn Ala Lys 
545                 550             


<210>  9491
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83630.1__F-del

<400>  9491

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Arg Ala Arg 
545                 550             


<210>  9492
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39505.1__F-del

<400>  9492

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9493
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY70242.1__F-del

<400>  9493

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9494
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY70198.1__F-del

<400>  9494

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Glu Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Val Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9495
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AII30203.1__F-del

<400>  9495

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Lys Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Arg Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9496
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21463.1__F-del

<400>  9496

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Val Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9497
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21397.1__F-del

<400>  9497

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Thr Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9498
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21320.1__F-del

<400>  9498

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Glu Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9499
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21298.1__F-del

<400>  9499

Met Glu Leu Met Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Ile Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9500
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21287.1__F-del

<400>  9500

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9501
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21276.1__F-del

<400>  9501

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9502
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21254.1__F-del

<400>  9502

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Ser Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9503
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21199.1__F-del

<400>  9503

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Ile Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9504
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21176.1__F-del

<400>  9504

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9505
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57537.1__F-del

<400>  9505

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Ser Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9506
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57471.1__F-del

<400>  9506

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Ser Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9507
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57427.1__F-del

<400>  9507

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Lys 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9508
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57042.1__F-del

<400>  9508

Met Glu Leu Leu Ile His Arg Ser Ser Val Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9509
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95981.1__F-del

<400>  9509

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Ile Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asn Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9510
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95893.1__F-del

<400>  9510

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Val Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9511
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95871.1__F-del

<400>  9511

Met Glu Leu Leu Ile His Lys Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Ile Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9512
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95816.1__F-del

<400>  9512

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ile Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Ser Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9513
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95772.1__F-del

<400>  9513

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Thr Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9514
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95629.1__F-del

<400>  9514

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Thr Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9515
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95673.1__F-del

<400>  9515

Met Glu Ser Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9516
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95596.1__F-del

<400>  9516

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Val Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9517
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95585.1__F-del

<400>  9517

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Ser Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asp Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9518
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95552.1__F-del

<400>  9518

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9519
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57570.1__F-del

<400>  9519

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Lys Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9520
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57152.1__F-del

<400>  9520

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Tyr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9521
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57064.1__F-del

<400>  9521

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Gly Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Tyr Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9522
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57009.1__F-del

<400>  9522

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Ile 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9523
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX56987.1__F-del

<400>  9523

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Ile Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9524
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV82100.1__F-del

<400>  9524

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9525
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV82001.1__F-del

<400>  9525

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9526
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81891.1__F-del

<400>  9526

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9527
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81880.1__F-del

<400>  9527

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9528
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81836.1__F-del

<400>  9528

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Cys Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9529
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81682.1__F-del

<400>  9529

Met Glu Leu Pro Val Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9530
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81649.1__F-del

<400>  9530

Met Glu Leu Pro Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9531
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81484.1__F-del

<400>  9531

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9532
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81462.1__F-del

<400>  9532

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Arg Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9533
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81385.1__F-del

<400>  9533

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9534
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81363.1__F-del

<400>  9534

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Val Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9535
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81330.1__F-del

<400>  9535

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Phe Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9536
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81253.1__F-del

<400>  9536

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Asn Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9537
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81154.1__F-del

<400>  9537

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9538
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81122.1__F-del

<400>  9538

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Asn Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Lys Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9539
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81089.1__F-del

<400>  9539

Met Gly Leu Leu Ile His Gly Ser Ser Ala Val Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9540
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81012.1__F-del

<400>  9540

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Asn Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9541
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80957.1__F-del

<400>  9541

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn His Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9542
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80880.1__F-del

<400>  9542

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Ile Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9543
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80869.1__F-del

<400>  9543

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Arg Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9544
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80836.1__F-del

<400>  9544

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Ala Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9545
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80803.1__F-del

<400>  9545

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asp Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9546
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39559.1__F-del

<400>  9546

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Gln Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9547
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39562.1__F-del

<400>  9547

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ser Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9548
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39556.1__F-del

<400>  9548

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Met Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9549
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39550.1__F-del

<400>  9549

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9550
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39547.1__F-del

<400>  9550

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Leu Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9551
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39544.1__F-del

<400>  9551

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Ile Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9552
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39541.1__F-del

<400>  9552

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9553
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39529.1__F-del

<400>  9553

Met Glu Leu Leu Ile His Arg Ser Asn Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9554
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39526.1__F-del

<400>  9554

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asn Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9555
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39523.1__F-del

<400>  9555

Met Glu Leu Leu Ile His Arg Ser Ile Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Thr Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9556
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39514.1__F-del

<400>  9556

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Val Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Tyr Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9557
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39502.1__F-del

<400>  9557

Met Glu Leu Leu Val His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Asn Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Ala Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9558
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39499.1__F-del

<400>  9558

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9559
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39496.1__F-del

<400>  9559

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Ile Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Thr Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9560
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39493.1__F-del

<400>  9560

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Gln Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9561
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39484.1__F-del

<400>  9561

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Thr Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9562
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39490.1__F-del

<400>  9562

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9563
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39487.1__F-del

<400>  9563

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Val Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Met Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Ile Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Arg Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9564
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39475.1__F-del

<400>  9564

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Gln Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9565
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39466.1__F-del

<400>  9565

Met Glu Leu Leu Ile Leu Lys Ala Asn Val Ile Ala Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Ser Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9566
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39463.1__F-del

<400>  9566

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Asn Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9567
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39454.1__F-del

<400>  9567

Met Glu Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Val Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9568
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39442.1__F-del

<400>  9568

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Ser Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9569
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39439.1__F-del

<400>  9569

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Arg Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9570
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39436.1__F-del

<400>  9570

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Phe Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9571
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39415.1__F-del

<400>  9571

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9572
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39403.1__F-del

<400>  9572

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Met Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9573
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39397.1__F-del

<400>  9573

Met Glu Leu Pro Ile Ile Lys Ala Asn Ala Ile Thr Thr Ile Leu Ile 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Thr Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9574
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39391.1__F-del

<400>  9574

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Val Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9575
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGG39379.1__F-del

<400>  9575

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Thr Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9576
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHL84194.1__F-del

<400>  9576

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9577
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA84012.1__F-del

<400>  9577

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Met Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9578
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHJ60043.1__F-del

<400>  9578

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Thr Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln His Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9579
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BAO49770.1__F-del

<400>  9579

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Gly Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Pro Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9580
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BAO49766.1__F-del

<400>  9580

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Pro Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Gly Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9581
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BAO49767.1__F-del

<400>  9581

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Cys Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9582
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA84034.1__F-del

<400>  9582

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asp Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9583
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA84023.1__F-del

<400>  9583

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Phe Ala 
1               5                   10                  15      


Thr Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9584
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83990.1__F-del

<400>  9584

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Phe Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9585
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83957.1__F-del

<400>  9585

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Val Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Val Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9586
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83924.1__F-del

<400>  9586

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Phe Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9587
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83891.1__F-del

<400>  9587

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Ala Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9588
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83880.1__F-del

<400>  9588

Met Asp Leu Pro Ile Leu Lys Ile Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9589
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83782.1__F-del

<400>  9589

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9590
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83760.1__F-del

<400>  9590

Met Glu Leu Pro Ile Ile Asn Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Met Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Asn Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9591
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83694.1__F-del

<400>  9591

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Asp Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9592
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGT75357.1__F-del

<400>  9592

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Ile Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9593
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN92848.1__F-del

<400>  9593

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Ile Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Leu Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9594
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28792.1__F-del

<400>  9594

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Met Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9595
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28781.1__F-del

<400>  9595

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9596
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28759.1__F-del

<400>  9596

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Ile Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9597
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28748.1__F-del

<400>  9597

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Ile Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9598
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28693.1__F-del

<400>  9598

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Lys Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9599
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28638.1__F-del

<400>  9599

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Gln 
545                 550             


<210>  9600
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28627.1__F-del

<400>  9600

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Arg Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9601
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28539.1__F-del

<400>  9601

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Ile Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Pro Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9602
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28528.1__F-del

<400>  9602

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Ser 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9603
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28462.1__F-del

<400>  9603

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Met Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9604
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28440.1__F-del

<400>  9604

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Ile Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Val Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9605
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGL96787.1__F-del

<400>  9605

Met Glu Val Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ala Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9606
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGL96786.1__F-del

<400>  9606

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Thr Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9607
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGL96784.1__F-del

<400>  9607

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Thr Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Arg Ala Arg 
545                 550             


<210>  9608
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93662.1__F-del

<400>  9608

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ser 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Gln Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9609
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93657.1__F-del

<400>  9609

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Leu Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr His Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9610
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93656.1__F-del

<400>  9610

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Ile Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Arg Ala Arg 
545                 550             


<210>  9611
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93659.1__F-del

<400>  9611

Met Glu Leu Val Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Val Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9612
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93660.1__F-del

<400>  9612

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Val Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9613
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93663.1__F-del

<400>  9613

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Phe Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9614
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93664.1__F-del

<400>  9614

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


His Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9615
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAS93655.1__F-del

<400>  9615

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ala Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Glu Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9616
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54517.1__F-del

<400>  9616

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9617
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87348.1__F-del

<400>  9617

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9618
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87341.1__F-del

<400>  9618

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Lys Asn Arg Leu Leu Glu Asn Thr Lys Glu Phe Ser Val Tyr 
225                 230                 235                 240 


Leu Gly Val Thr Thr Pro Leu Gly Thr Phe Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser His Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9619
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87344.1__F-del

<400>  9619

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Leu Ser Val Leu Thr Ser Lys Gly 
            180                 185                 190         


Leu Asn Pro Lys Asn Tyr Ile Glu Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Gly Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9620
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87351.1__F-del

<400>  9620

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9621
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87338.1__F-del

<400>  9621

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Pro Phe Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9622
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87342.1__F-del

<400>  9622

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Met 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ala Thr Ile Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9623
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87352.1__F-del

<400>  9623

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Ala Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile His Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser His Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9624
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87337.1__F-del

<400>  9624

Met Glu Leu Pro Ile Leu Lys Gln Asn Ala Ile Thr Ser Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Trp Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9625
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87336.1__F-del

<400>  9625

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9626
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ98756.1__F-del

<400>  9626

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9627
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ98757.1__F-del

<400>  9627

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Ile Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9628
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ98755.1__F-del

<400>  9628

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Ala Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9629
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ98752.1__F-del

<400>  9629

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Val Val Ser Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Ile Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9630
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ98753.1__F-del

<400>  9630

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ile Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9631
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ98747.1__F-del

<400>  9631

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Thr Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9632
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87325.1__F-del

<400>  9632

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Lys Glu Leu Gln 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9633
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87326.1__F-del

<400>  9633

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Ala Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asp Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9634
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__5W23_A__F-del

<400>  9634

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Ser Ala Ile Gly Gly Tyr Ile Pro Glu Ala Pro Arg Asp Gly Gln 
        515                 520                 525             


Ala Tyr Val Arg Lys Asp Gly Glu Trp Val Leu Leu Ser Thr Phe Leu 
    530                 535                 540                 


Gly Gly Leu Val Pro Arg Gly Ser His 
545                 550             


<210>  9635
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__5EA3_F__F-del

<400>  9635

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Cys Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Phe Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Cys Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Ser Ala Ile Gly Gly Tyr Ile Pro Glu Ala Pro Arg Asp Gly Gln 
        515                 520                 525             


Ala Tyr Val Arg Lys Asp Gly Glu Trp Val Leu Leu Ser Thr Phe Leu 
    530                 535                 540                 


Gly Gly Leu Val Pro Arg Gly Ser His 
545                 550             


<210>  9636
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__5UDD_A__F-del

<400>  9636

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Thr Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Cys Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Phe Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Ser Tyr Ile Asn Asn Gln Leu Leu Pro Ile Leu Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Cys Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu Ser Ala Ile Gly Gly Tyr Ile Pro Glu Ala Pro Arg Asp Gly Gln 
        515                 520                 525             


Ala Tyr Val Arg Lys Asp Gly Glu Trp Val Leu Leu Ser Thr Phe Leu 
    530                 535                 540                 


Gly Gly Leu Val Pro Arg Gly Ser His 
545                 550             


<210>  9637
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__5EA8_F__F-del

<400>  9637

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Cys Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Phe Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Leu Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Cys Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Tyr Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu Ser Ala Ile Gly Gly Tyr Ile Pro Glu Ala Pro Arg Asp Gly Gln 
        515                 520                 525             


Ala Tyr Val Arg Lys Asp Gly Glu Trp Val Leu Leu Ser Thr Phe Leu 
    530                 535                 540                 


Gly Gly Leu Val Pro Arg Gly Ser His 
545                 550             


<210>  9638
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54458.1__F-del

<400>  9638

Met Glu Phe Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Gln Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9639
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEN74947.1__F-del

<400>  9639

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Ala Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asn Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9640
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54485.1__F-del

<400>  9640

Met Asp Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9641
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54477.1__F-del

<400>  9641

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Ile Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asn Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9642
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54451.1__F-del

<400>  9642

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Thr Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9643
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54463.1__F-del

<400>  9643

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Asn Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Thr Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9644
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54445.1__F-del

<400>  9644

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Gly Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9645
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO12131.1__F-del

<400>  9645

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Thr Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asp Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9646
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEN74945.1__F-del

<400>  9646

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Thr Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Asn Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Arg Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9647
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEN74944.1__F-del

<400>  9647

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Met Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Gly Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Cys Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9648
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASF87335.1__F-del

<400>  9648

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Gln 
            100                 105                 110         


Arg Phe Thr Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Ile Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Ala Ile Leu Ser Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9649
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54515.1__F-del

<400>  9649

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ala Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9650
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA61605.1__F-del

<400>  9650

Met Glu Leu Leu Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Ser Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His His Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9651
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81660.1__F-del

<400>  9651

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Ser Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9652
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHG54441.1__F-del

<400>  9652

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Ile Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Gln 
545                 550             


<210>  9653
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(Memphis-37)__AIY60640.1__F-del

<400>  9653

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9654
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABQ42594.1__F-del

<400>  9654

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Val Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9655
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACO83297.1__F-del

<400>  9655

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Met Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Arg Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Lys Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Tyr Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9656
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ACO83301.1__F-del

<400>  9656

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Asn Lys Cys Asn Gly Thr Asp Ala Lys Ile Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9657
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95775.1__F-del

<400>  9657

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Gln Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn His Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Glu 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9658
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ADZ95779.1__F-del

<400>  9658

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Phe Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Leu Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9659
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63597.1__F-del

<400>  9659

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Ile Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9660
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63608.1__F-del

<400>  9660

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Thr Ala Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9661
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63630.1__F-del

<400>  9661

Met Glu Leu Leu Ile His Arg Ser Ser Ala Ile Phe Leu Thr Leu Ala 
1               5                   10                  15      


Ile Asn Ala Leu Tyr Leu Thr Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Arg Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Thr Lys Cys Asn Gly Thr Asp Thr Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Asn Thr Pro Ala Val Asn Asn Arg Ala Arg Arg Glu Ala Pro 
            100                 105                 110         


Gln Tyr Met Asn Tyr Thr Ile Asn Thr Thr Lys Asn Leu Asn Val Ser 
        115                 120                 125             


Ile Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asn Asn Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Gln Gln Ser Cys Arg Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Ser Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Arg Val Thr Thr Pro Leu Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Ser Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Ile Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Ile Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Asp Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Ser Leu Cys Asn Thr 
    370                 375                 380                 


Asp Ile Phe Asn Ser Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Ile Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Leu Glu Gly 
    450                 455                 460                 


Lys Asn Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Tyr Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Arg Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Thr Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Ala Ile Ile Ile Val Ile Ile Val Val Leu Leu Ser Leu Ile Ala Ile 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Lys 
545                 550             


<210>  9662
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHE57683.1__F-del

<400>  9662

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9663
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHE57894.1__F-del

<400>  9663

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Ile Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9664
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80511.1__F-del

<400>  9664

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Thr Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Lys Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9665
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80560.1__F-del

<400>  9665

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9666
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80660.1__F-del

<400>  9666

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Ser Leu Cys Leu Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9667
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80670.1__F-del

<400>  9667

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9668
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80760.1__F-del

<400>  9668

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Ile Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9669
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80800.1__F-del

<400>  9669

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Ile Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9670
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80860.1__F-del

<400>  9670

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Leu Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9671
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80990.1__F-del

<400>  9671

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Leu Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9672
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81370.1__F-del

<400>  9672

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Ala Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ser Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9673
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX22013.1__F-del

<400>  9673

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Ile Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9674
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA62675.1__F-del

<400>  9674

Met Glu Leu Pro Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Phe Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9675
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA62685.1__F-del

<400>  9675

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Phe Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9676
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63044.1__F-del

<400>  9676

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Pro Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9677
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63234.1__F-del

<400>  9677

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Phe Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9678
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63364.1__F-del

<400>  9678

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Ile Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9679
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63604.1__F-del

<400>  9679

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Asn Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9680
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUH26189.1__F-del

<400>  9680

Met Asp Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Leu Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Asn Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Arg Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Val Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Leu Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Phe Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9681
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__NP_044596.1__F-del

<400>  9681

Met Glu Leu Pro Ile Leu Lys Thr Asn Ala Ile Thr Ala Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Thr Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Ser Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Leu Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Ile Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9682
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__1701388A__F-del

<400>  9682

Met Glu Leu Pro Ile Leu Lys Thr Asn Thr Ile Thr Thr Ile Leu Ala 
1               5                   10                  15      


Ala Val Thr Leu Cys Phe Ala Ser Ser Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Glu Asn Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Ala Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Thr Lys Asn Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Ile Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Ala Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Ile 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Val Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9683
<211>  553
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__WP_079890144.1__F-del

<400>  9683

Met Glu Leu Leu Ile Leu Lys Ala Asn Ala Ile Thr Thr Ile Leu Thr 
1               5                   10                  15      


Ala Val Thr Phe Cys Phe Ala Ser Gly Gln Asn Ile Thr Glu Glu Phe 
            20                  25                  30          


Tyr Gln Ser Thr Cys Ser Ala Val Ser Lys Gly Tyr Leu Ser Ala Leu 
        35                  40                  45              


Arg Thr Gly Trp Tyr Thr Ser Val Ile Thr Ile Glu Leu Ser Asn Ile 
    50                  55                  60                  


Lys Lys Ile Lys Cys Asn Gly Thr Asp Ala Lys Val Lys Leu Ile Lys 
65                  70                  75                  80  


Gln Glu Leu Asp Lys Tyr Lys Asn Ala Val Thr Glu Leu Gln Leu Leu 
                85                  90                  95      


Met Gln Ser Thr Pro Ala Thr Asn Asn Arg Ala Arg Arg Glu Leu Pro 
            100                 105                 110         


Arg Phe Met Asn Tyr Thr Leu Asn Asn Ala Lys Lys Thr Asn Val Thr 
        115                 120                 125             


Leu Ser Lys Lys Arg Lys Arg Arg Phe Leu Gly Phe Leu Leu Gly Val 
    130                 135                 140                 


Gly Ser Ala Ile Ala Ser Gly Val Ala Val Ser Lys Val Leu His Leu 
145                 150                 155                 160 


Glu Gly Glu Val Asn Lys Ile Lys Ser Ala Leu Leu Ser Thr Asn Lys 
                165                 170                 175     


Ala Val Val Ser Leu Ser Asn Gly Val Ser Val Leu Thr Ser Lys Val 
            180                 185                 190         


Leu Asp Leu Lys Asn Tyr Ile Asp Lys Gln Leu Leu Pro Ile Val Asn 
        195                 200                 205             


Lys Gln Ser Cys Ser Ile Ser Asn Ile Glu Thr Val Ile Glu Phe Gln 
    210                 215                 220                 


Gln Lys Asn Asn Arg Leu Leu Glu Ile Thr Arg Glu Phe Ser Val Asn 
225                 230                 235                 240 


Val Gly Val Thr Thr Pro Val Ser Thr Tyr Met Leu Thr Asn Ser Glu 
                245                 250                 255     


Leu Leu Ser Leu Ile Asn Asp Met Pro Ile Thr Asn Asp Gln Lys Lys 
            260                 265                 270         


Leu Met Ser Asn Asn Val Gln Ile Val Arg Gln Gln Ser Tyr Ser Ile 
        275                 280                 285             


Met Ser Ile Ile Lys Glu Glu Val Leu Ala Tyr Val Val Gln Leu Pro 
    290                 295                 300                 


Leu Tyr Gly Val Ile Asp Thr Pro Cys Trp Lys Leu His Thr Ser Pro 
305                 310                 315                 320 


Leu Cys Thr Thr Asn Thr Lys Glu Gly Ser Asn Ile Cys Leu Thr Arg 
                325                 330                 335     


Thr Asp Arg Gly Trp Tyr Cys Asp Asn Ala Gly Ser Val Ser Phe Phe 
            340                 345                 350         


Pro Gln Ala Glu Thr Cys Lys Val Gln Ser Asn Arg Val Phe Cys Asp 
        355                 360                 365             


Thr Met Asn Ser Leu Thr Leu Pro Ser Glu Val Asn Leu Cys Asn Val 
    370                 375                 380                 


Asp Ile Phe Asn Pro Lys Tyr Asp Cys Lys Ile Met Thr Ser Lys Thr 
385                 390                 395                 400 


Asp Val Ser Ser Ser Val Ile Thr Ser Leu Gly Ala Ile Val Ser Cys 
                405                 410                 415     


Tyr Gly Lys Thr Lys Cys Thr Ala Ser Asn Lys Asn Arg Gly Ile Ile 
            420                 425                 430         


Lys Thr Phe Ser Asn Gly Cys Asp Tyr Val Ser Asn Lys Gly Val Asp 
        435                 440                 445             


Thr Val Ser Val Gly Asn Thr Leu Tyr Tyr Val Asn Lys Gln Glu Gly 
    450                 455                 460                 


Lys Ser Leu Tyr Val Lys Gly Glu Pro Ile Ile Asn Phe Tyr Asp Pro 
465                 470                 475                 480 


Leu Val Phe Pro Ser Asp Glu Phe Asp Ala Ser Ile Ser Gln Val Asn 
                485                 490                 495     


Glu Lys Ile Asn Gln Ser Leu Ala Phe Ile Arg Lys Ser Asp Glu Leu 
            500                 505                 510         


Leu His Asn Val Asn Ala Gly Lys Ser Thr Thr Asn Ile Met Ile Thr 
        515                 520                 525             


Thr Ile Ile Ile Val Ile Ile Val Ile Leu Leu Ser Leu Ile Ala Val 
    530                 535                 540                 


Gly Leu Leu Leu Tyr Cys Lys Ala Arg 
545                 550             


<210>  9684
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9684

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  9685
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9685
auggaaacau acgugaacaa gcuucacgaa ggcuccacau acacagcugc uguucaauac       60

aaugucuuag aaaaagacga ugacccugca ucacuuacaa uaugggugcc cauguuccaa      120

ucaucuaugc cagcagauuu acuuauaaaa gaacuagcua augucaacau acuagugaaa      180

caaauaucca cacccaaggg accuucacua agagucauga uaaacucaag aagugcagug      240

cuagcacaaa ugcccagcaa auuuaccaua ugcgcuaaug uguccuugga ugaaagaagc      300

aaacuagcau augauguaac cacacccugu gaaaucaagg cauguagucu aacaugccua      360

aaaucaaaaa auauguugac uacaguuaaa gaucucacua ugaagacacu caacccuaca      420

caugauauua uugcuuuaug ugaauuugaa aacauaguaa caucaaaaaa agucauaaua      480

ccaacauacc uaagauccau cagugucaga aauaaagauc ugaacacacu ugaaaauaua      540

acaaccacug aauucaaaaa ugcuaucaca aaugcaaaaa ucaucccuua cucaggauua      600

cuauuaguca ucacagugac ugacaacaaa ggagcauuca aauacauaaa gccacaaagu      660

caauucauag uagaucuugg agcuuaccua gaaaaagaaa guauauauua uguuaccaca      720

aauuggaagc acacagcuac acgauuugca aucaaaccca uggaagauua a               771


<210>  9686
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9686
auggagaccu acgugaacaa gcugcacgag ggcagcaccu acacggccgc cguccaguac       60

aacgugcucg agaaggacga cgaccccgcg ucccugacca ucugggugcc gauguuccag      120

agcuccaugc ccgccgaccu gcucaucaag gagcuggcca acgucaacau ccuggugaag      180

cagaucagca cccccaaggg gcccucccuc cgcgugauga ucaacagccg guccgccguc      240

cuggcccaga ugccgagcaa guucaccauc ugcgcgaacg ugucccugga cgagcgcagc      300

aagcucgccu acgacgugac gacccccugc gagaucaagg ccugcucccu gaccugccuc      360

aagagcaaga acaugcugac cacggucaag gaccugacca ugaagacccu gaaccccacc      420

cacgacauca ucgcccucug cgaguucgag aacaucguga cguccaagaa ggugaucauc      480

cccaccuacc ugcggagcau cuccguccgc aacaaggacc ugaacacccu cgagaacauc      540

accacgaccg aguucaagaa cgcgaucacc aacgccaaga ucaucccgua cagcggccug      600

cugcucguga ucaccgugac ggacaacaag ggggccuuca aguacaucaa gccccagucc      660

caguucaucg ucgaccuggg cgccuaccug gagaaggaga gcaucuacua cgugaccacc      720

aacuggaagc acaccgccac gcgguucgcg aucaagccca uggaggacug a               771


<210>  9687
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9687
auggagaccu acgucaacaa gcuccacgag ggcuccaccu acaccgccgc cguccaguac       60

aacguccucg agaaggacga cgaccccgcc ucccucacca ucuggguccc cauguuccag      120

uccuccaugc ccgccgaccu ccucaucaag gagcucgcca acgucaacau ccucgucaag      180

cagaucucca cccccaaggg ccccucccuc cgcgucauga ucaacucccg cuccgccguc      240

cucgcccaga ugcccuccaa guucaccauc ugcgccaacg ucucccucga cgagcgcucc      300

aagcucgccu acgacgucac cacccccugc gagaucaagg ccugcucccu caccugccuc      360

aaguccaaga acaugcucac caccgucaag gaccucacca ugaagacccu caaccccacc      420

cacgacauca ucgcccucug cgaguucgag aacaucguca ccuccaagaa ggucaucauc      480

cccaccuacc uccgcuccau cuccguccgc aacaaggacc ucaacacccu cgagaacauc      540

accaccaccg aguucaagaa cgccaucacc aacgccaaga ucauccccua cuccggccuc      600

cuccucguca ucaccgucac cgacaacaag ggcgccuuca aguacaucaa gccccagucc      660

caguucaucg ucgaccucgg cgccuaccuc gagaaggagu ccaucuacua cgucaccacc      720

aacuggaagc acaccgccac ccgcuucgcc aucaagccca uggaggacug a               771


<210>  9688
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9688
auggagaccu acgugaacaa gcugcacgaa ggcagcacau auacugccgc uguccaguac       60

aauguucucg agaaagacga ugaccccgca ucccuuacga ucugggugcc uauguuccaa      120

ucuucaaugc cagccgaucu guugauuaag gaauuagcga acguaaauau acuggugaaa      180

cagaucagua ccccgaaggg gcccagccua agagucauga uuaacuccag gucugcugug      240

cucgcccaga ugccuucgaa auuuacaauc ugcgcaaaug uuucacugga cgagcggagc      300

aaacuugccu augaugugac uaccccaugu gaaauuaagg cuugcagucu gacauguuug      360

aaguccaaga acaugcucac cacugucaaa gaccugacaa ugaagacccu gaaucccacg      420

caugauauca uagcacucug cgaguucgag aacaucguga cuucuaaaaa gguaauuauc      480

ccuaccuacu uacgcagcau uuccguucga aauaaggacc ugaacacacu ugaaaauauc      540

acuaccacag aguuuaaaaa cgccauaacc aaugcuaaga uuaucccaua uucaggauug      600

cugcuaguga uuacggucac ugauaacaaa ggugccuuca aguacaucaa accccagagu      660

caauuuaucg uggaccucgg cgcguaucug gaaaaggaga gcauuuacua cgugacaacc      720

aauuggaaac acacugcaac acguuucgcc auaaagccua uggaggauug a               771


<210>  9689
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9689
auggagaccu acgugaacaa gcugcacgag ggcagcaccu acaccgccgc cgugcaguac       60

aacgugcugg agaaggacga cgaccccgcc agccugacca ucugggugcc cauguuccag      120

agcagcaugc ccgccgaccu gcugaucaag gagcuggcca acgugaacau ccuggugaag      180

cagaucagca cccccaaggg ccccagccug agagugauga ucaacagcag aagcgccgug      240

cuggcccaga ugcccagcaa guucaccauc ugcgccaacg ugagccugga cgagagaagc      300

aagcuggccu acgacgugac cacccccugc gagaucaagg ccugcagccu gaccugccug      360

aagagcaaga acaugcugac caccgugaag gaccugacca ugaagacccu gaaccccacc      420

cacgacauca ucgcccugug cgaguucgag aacaucguga ccagcaagaa ggugaucauc      480

cccaccuacc ugagaagcau cagcgugaga aacaaggacc ugaacacccu ggagaacauc      540

accaccaccg aguucaagaa cgccaucacc aacgccaaga ucauccccua cagcggccug      600

cugcugguga ucaccgugac cgacaacaag ggcgccuuca aguacaucaa gccccagagc      660

caguucaucg uggaccuggg cgccuaccug gagaaggaga gcaucuacua cgugaccacc      720

aacuggaagc acaccgccac cagauucgcc aucaagccca uggaggacug a               771


<210>  9690
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9690
auggagaccu acgugaacaa gcugcacgaa ggcagcacau auacggccgc uguccaguac       60

aauguucucg agaaagacga ugaccccgcc ucccugacca ucugggugcc uauguuccaa      120

ucuagcaugc cggcggaucu ucugauuaag gaacucgcua acgugaauau ccuggucaaa      180

cagauuucca cacccaaggg gccuucucuu agagugauga ucaacagccg guccgccguu      240

cuggcccaga ugcccucuaa auuuaccauu ugcgcuaaug ugagccucga cgagcgcucc      300

aagcuggccu augaugucac aaccccuugu gaaaucaagg cuugcagccu gacaugucuc      360

aaaucuaaga acaugcugac cacggugaaa gaccuuacca ugaagacacu gaaucccacc      420

caugauauca uugcccucug cgaguucgag aacaucguua cauccaaaaa ggugauuauc      480

ccuaccuacc ugagaagcau uucuguccgg aauaaggacc uuaacacgcu ggaaaauauc      540

acaaccacag aguuuaaaaa cgcgauuacc aaugccaaga ucaucccgua uuccggacuc      600

cugcugguga uuaccgugac agauaacaaa ggcgcuuuca aguacaucaa accccagagc      660

caauuuauug ucgaccucgg ggccuaucug gaaaaggagu cuaucuacua cguuacgacc      720

aauuggaaac acacagcuac ccgcuucgcc auuaagccua uggaggauug a               771


<210>  9691
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9691
auggaaacau acguaaacaa acuacacgaa ggauccacau acacagcagc aguacaauac       60

aacguacuag aaaaagacga cgacccagca ucuuuaacca uauggguacc aauguuccaa      120

ucaucaaugc cagcagaccu cuuaauaaaa gaacuagcaa acguaaacau ccuagucaaa      180

caaauaucaa cacccaaagg accaucccuc agaguaauga ucaacucaag aucagcagua      240

cuagcacaaa ugccaucaaa auucacaaua ugcgccaacg uuucuuuaga cgaacgauca      300

aaauuagccu acgacguaac aacacccugc gaaauaaaag caugcucacu aacaugccua      360

aaaucaaaaa acaugcucac uacaguaaaa gaccuaacca ugaaaacacu caacccaaca      420

cacgacauaa uagcccuaug cgaauuugaa aacauaguaa caucaaaaaa aguaauaauc      480

ccaacauacu uaagaucgau cucagucaga aacaaagacc uaaauacacu cgaaaacaua      540

acaacaacag aauuuaaaaa cgcaauaaca aacgcaaaaa uaauaccaua cucaggacua      600

cuccuaguaa uaacaguaac agacaacaaa ggagcauuca aauacauaaa accacaauca      660

caauucaucg uagaccucgg agcauaccua gaaaaagaau caauauacua cguaacaaca      720

aacuggaaac acaccgccac aagauucgca auaaaaccca uggaagacua a               771


<210>  9692
<211>  771
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__P0DOE7.1__M

<400>  9692
auggaaaccu acgucaacaa acuacacgaa ggcucaaccu acaccgccgc cguccaauac       60

aacguccucg aaaaagacga cgaccccgcc ucccuaacca ucuggguucc cauguuccaa      120

ucauccaugc ccgccgaccu ccucauaaaa gaacuagcca acgucaacau ccuagucaaa      180

caaaucagca cccccaaagg ccccucccuc cgcguaauga ucaacucccg cuccgccguc      240

cuagcccaaa ugcccuccaa auuuacaauc ugcgccaacg ucucccucga cgaacgcuca      300

aaacucgccu acgacgucac cacacccugc gaaaucaaag ccugcucccu caccugccuc      360

aaaagcaaaa auaugcuaac caccgucaaa gaccuuacca ugaaaacccu caaccccacu      420

cacgacauca uagcccucug cgaauuugaa aacaucguca ccuccaaaaa agucaucauc      480

cccacauacc uccgcuccau cuccguccgc aacaaagacc ucaacacccu cgaaaacauc      540

accaccaccg aauuuaaaaa cgccaucacc aacgccaaaa ucauccccua cuccggccuc      600

cuccucguca ucaccguuac cgacaacaaa ggcgccuuca aauacaucaa accccaaucc      660

caauucaucg ucgaccucgg agccuaccuu gaaaaagagu ccaucuacua cgucaccacc      720

aacuggaaac acaccgccac ccgauucgcc aucaaaccca uggaagacua a               771


<210>  9693
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9693
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg ugaacaagcu ucacgaaggc uccacauaca      120

cagcugcugu ucaauacaau gucuuagaaa aagacgauga cccugcauca cuuacaauau      180

gggugcccau guuccaauca ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug      240

ucaacauacu agugaaacaa auauccacac ccaagggacc uucacuaaga gucaugauaa      300

acucaagaag ugcagugcua gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu      360

ccuuggauga aagaagcaaa cuagcauaug auguaaccac acccugugaa aucaaggcau      420

guagucuaac augccuaaaa ucaaaaaaua uguugacuac aguuaaagau cucacuauga      480

agacacucaa cccuacacau gauauuauug cuuuauguga auuugaaaac auaguaacau      540

caaaaaaagu cauaauacca acauaccuaa gauccaucag ugucagaaau aaagaucuga      600

acacacuuga aaauauaaca accacugaau ucaaaaaugc uaucacaaau gcaaaaauca      660

ucccuuacuc aggauuacua uuagucauca cagugacuga caacaaagga gcauucaaau      720

acauaaagcc acaaagucaa uucauaguag aucuuggagc uuaccuagaa aaagaaagua      780

uauauuaugu uaccacaaau uggaagcaca cagcuacacg auuugcaauc aaacccaugg      840

aagauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9694
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9694
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

cggccgccgu ccaguacaac gugcucgaga aggacgacga ccccgcgucc cugaccaucu      180

gggugccgau guuccagagc uccaugcccg ccgaccugcu caucaaggag cuggccaacg      240

ucaacauccu ggugaagcag aucagcaccc ccaaggggcc cucccuccgc gugaugauca      300

acagccgguc cgccguccug gcccagaugc cgagcaaguu caccaucugc gcgaacgugu      360

cccuggacga gcgcagcaag cucgccuacg acgugacgac ccccugcgag aucaaggccu      420

gcucccugac cugccucaag agcaagaaca ugcugaccac ggucaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgugacgu      540

ccaagaaggu gaucaucccc accuaccugc ggagcaucuc cguccgcaac aaggaccuga      600

acacccucga gaacaucacc acgaccgagu ucaagaacgc gaucaccaac gccaagauca      660

ucccguacag cggccugcug cucgugauca ccgugacgga caacaagggg gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccacgcg guucgcgauc aagcccaugg      840

aggacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9695
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9695
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ucaacaagcu ccacgagggc uccaccuaca      120

ccgccgccgu ccaguacaac guccucgaga aggacgacga ccccgccucc cucaccaucu      180

ggguccccau guuccagucc uccaugcccg ccgaccuccu caucaaggag cucgccaacg      240

ucaacauccu cgucaagcag aucuccaccc ccaagggccc cucccuccgc gucaugauca      300

acucccgcuc cgccguccuc gcccagaugc ccuccaaguu caccaucugc gccaacgucu      360

cccucgacga gcgcuccaag cucgccuacg acgucaccac ccccugcgag aucaaggccu      420

gcucccucac cugccucaag uccaagaaca ugcucaccac cgucaaggac cucaccauga      480

agacccucaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgucaccu      540

ccaagaaggu caucaucccc accuaccucc gcuccaucuc cguccgcaac aaggaccuca      600

acacccucga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacuc cggccuccuc cucgucauca ccgucaccga caacaagggc gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accucggcgc cuaccucgag aaggagucca      780

ucuacuacgu caccaccaac uggaagcaca ccgccacccg cuucgccauc aagcccaugg      840

aggacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9696
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9696
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cugccgcugu ccaguacaau guucucgaga aagacgauga ccccgcaucc cuuacgaucu      180

gggugccuau guuccaaucu ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg      240

uaaauauacu ggugaaacag aucaguaccc cgaaggggcc cagccuaaga gucaugauua      300

acuccagguc ugcugugcuc gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu      360

cacuggacga gcggagcaaa cuugccuaug augugacuac cccaugugaa auuaaggcuu      420

gcagucugac auguuugaag uccaagaaca ugcucaccac ugucaaagac cugacaauga      480

agacccugaa ucccacgcau gauaucauag cacucugcga guucgagaac aucgugacuu      540

cuaaaaaggu aauuaucccu accuacuuac gcagcauuuc cguucgaaau aaggaccuga      600

acacacuuga aaauaucacu accacagagu uuaaaaacgc cauaaccaau gcuaagauua      660

ucccauauuc aggauugcug cuagugauua cggucacuga uaacaaaggu gccuucaagu      720

acaucaaacc ccagagucaa uuuaucgugg accucggcgc guaucuggaa aaggagagca      780

uuuacuacgu gacaaccaau uggaaacaca cugcaacacg uuucgccaua aagccuaugg      840

aggauugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9697
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9697
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

ccgccgccgu gcaguacaac gugcuggaga aggacgacga ccccgccagc cugaccaucu      180

gggugcccau guuccagagc agcaugcccg ccgaccugcu gaucaaggag cuggccaacg      240

ugaacauccu ggugaagcag aucagcaccc ccaagggccc cagccugaga gugaugauca      300

acagcagaag cgccgugcug gcccagaugc ccagcaaguu caccaucugc gccaacguga      360

gccuggacga gagaagcaag cuggccuacg acgugaccac ccccugcgag aucaaggccu      420

gcagccugac cugccugaag agcaagaaca ugcugaccac cgugaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccugugcga guucgagaac aucgugacca      540

gcaagaaggu gaucaucccc accuaccuga gaagcaucag cgugagaaac aaggaccuga      600

acacccugga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacag cggccugcug cuggugauca ccgugaccga caacaagggc gccuucaagu      720

acaucaagcc ccagagccag uucaucgugg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccaccag auucgccauc aagcccaugg      840

aggacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9698
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9698
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cggccgcugu ccaguacaau guucucgaga aagacgauga ccccgccucc cugaccaucu      180

gggugccuau guuccaaucu agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg      240

ugaauauccu ggucaaacag auuuccacac ccaaggggcc uucucuuaga gugaugauca      300

acagccgguc cgccguucug gcccagaugc ccucuaaauu uaccauuugc gcuaauguga      360

gccucgacga gcgcuccaag cuggccuaug augucacaac cccuugugaa aucaaggcuu      420

gcagccugac augucucaaa ucuaagaaca ugcugaccac ggugaaagac cuuaccauga      480

agacacugaa ucccacccau gauaucauug cccucugcga guucgagaac aucguuacau      540

ccaaaaaggu gauuaucccu accuaccuga gaagcauuuc uguccggaau aaggaccuua      600

acacgcugga aaauaucaca accacagagu uuaaaaacgc gauuaccaau gccaagauca      660

ucccguauuc cggacuccug cuggugauua ccgugacaga uaacaaaggc gcuuucaagu      720

acaucaaacc ccagagccaa uuuauugucg accucggggc cuaucuggaa aaggagucua      780

ucuacuacgu uacgaccaau uggaaacaca cagcuacccg cuucgccauu aagccuaugg      840

aggauugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9699
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9699
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg uaaacaaacu acacgaagga uccacauaca      120

cagcagcagu acaauacaac guacuagaaa aagacgacga cccagcaucu uuaaccauau      180

ggguaccaau guuccaauca ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg      240

uaaacauccu agucaaacaa auaucaacac ccaaaggacc aucccucaga guaaugauca      300

acucaagauc agcaguacua gcacaaaugc caucaaaauu cacaauaugc gccaacguuu      360

cuuuagacga acgaucaaaa uuagccuacg acguaacaac acccugcgaa auaaaagcau      420

gcucacuaac augccuaaaa ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga      480

aaacacucaa cccaacacac gacauaauag cccuaugcga auuugaaaac auaguaacau      540

caaaaaaagu aauaauccca acauacuuaa gaucgaucuc agucagaaac aaagaccuaa      600

auacacucga aaacauaaca acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa      660

uaccauacuc aggacuacuc cuaguaauaa caguaacaga caacaaagga gcauucaaau      720

acauaaaacc acaaucacaa uucaucguag accucggagc auaccuagaa aaagaaucaa      780

uauacuacgu aacaacaaac uggaaacaca ccgccacaag auucgcaaua aaacccaugg      840

aagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9700
<211>  1047
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9700
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca      120

ccgccgccgu ccaauacaac guccucgaaa aagacgacga ccccgccucc cuaaccaucu      180

ggguucccau guuccaauca uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg      240

ucaacauccu agucaaacaa aucagcaccc ccaaaggccc cucccuccgc guaaugauca      300

acucccgcuc cgccguccua gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu      360

cccucgacga acgcucaaaa cucgccuacg acgucaccac acccugcgaa aucaaagccu      420

gcucccucac cugccucaaa agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga      480

aaacccucaa ccccacucac gacaucauag cccucugcga auuugaaaac aucgucaccu      540

ccaaaaaagu caucaucccc acauaccucc gcuccaucuc cguccgcaac aaagaccuca      600

acacccucga aaacaucacc accaccgaau uuaaaaacgc caucaccaac gccaaaauca      660

uccccuacuc cggccuccuc cucgucauca ccguuaccga caacaaaggc gccuucaaau      720

acaucaaacc ccaaucccaa uucaucgucg accucggagc cuaccuugaa aaagagucca      780

ucuacuacgu caccaccaac uggaaacaca ccgccacccg auucgccauc aaacccaugg      840

aagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      900

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1020

aaggcucuuu ucagagccac cagaauu                                         1047


<210>  9701
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9701
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu gaacaagcuu      120

cacgaaggcu ccacauacac agcugcuguu caauacaaug ucuuagaaaa agacgaugac      180

ccugcaucac uuacaauaug ggugcccaug uuccaaucau cuaugccagc agauuuacuu      240

auaaaagaac uagcuaaugu caacauacua gugaaacaaa uauccacacc caagggaccu      300

ucacuaagag ucaugauaaa cucaagaagu gcagugcuag cacaaaugcc cagcaaauuu      360

accauaugcg cuaauguguc cuuggaugaa agaagcaaac uagcauauga uguaaccaca      420

cccugugaaa ucaaggcaug uagucuaaca ugccuaaaau caaaaaauau guugacuaca      480

guuaaagauc ucacuaugaa gacacucaac ccuacacaug auauuauugc uuuaugugaa      540

uuugaaaaca uaguaacauc aaaaaaaguc auaauaccaa cauaccuaag auccaucagu      600

gucagaaaua aagaucugaa cacacuugaa aauauaacaa ccacugaauu caaaaaugcu      660

aucacaaaug caaaaaucau cccuuacuca ggauuacuau uagucaucac agugacugac      720

aacaaaggag cauucaaaua cauaaagcca caaagucaau ucauaguaga ucuuggagcu      780

uaccuagaaa aagaaaguau auauuauguu accacaaauu ggaagcacac agcuacacga      840

uuugcaauca aacccaugga agauuaagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9702
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9702
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac ggccgccguc caguacaacg ugcucgagaa ggacgacgac      180

cccgcguccc ugaccaucug ggugccgaug uuccagagcu ccaugcccgc cgaccugcuc      240

aucaaggagc uggccaacgu caacauccug gugaagcaga ucagcacccc caaggggccc      300

ucccuccgcg ugaugaucaa cagccggucc gccguccugg cccagaugcc gagcaaguuc      360

accaucugcg cgaacguguc ccuggacgag cgcagcaagc ucgccuacga cgugacgacc      420

cccugcgaga ucaaggccug cucccugacc ugccucaaga gcaagaacau gcugaccacg      480

gucaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgugacguc caagaaggug aucaucccca ccuaccugcg gagcaucucc      600

guccgcaaca aggaccugaa cacccucgag aacaucacca cgaccgaguu caagaacgcg      660

aucaccaacg ccaagaucau cccguacagc ggccugcugc ucgugaucac cgugacggac      720

aacaaggggg ccuucaagua caucaagccc cagucccagu ucaucgucga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccacgcgg      840

uucgcgauca agcccaugga ggacugagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9703
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9703
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu caacaagcuc      120

cacgagggcu ccaccuacac cgccgccguc caguacaacg uccucgagaa ggacgacgac      180

cccgccuccc ucaccaucug gguccccaug uuccaguccu ccaugcccgc cgaccuccuc      240

aucaaggagc ucgccaacgu caacauccuc gucaagcaga ucuccacccc caagggcccc      300

ucccuccgcg ucaugaucaa cucccgcucc gccguccucg cccagaugcc cuccaaguuc      360

accaucugcg ccaacgucuc ccucgacgag cgcuccaagc ucgccuacga cgucaccacc      420

cccugcgaga ucaaggccug cucccucacc ugccucaagu ccaagaacau gcucaccacc      480

gucaaggacc ucaccaugaa gacccucaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgucaccuc caagaagguc aucaucccca ccuaccuccg cuccaucucc      600

guccgcaaca aggaccucaa cacccucgag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacucc ggccuccucc ucgucaucac cgucaccgac      720

aacaagggcg ccuucaagua caucaagccc cagucccagu ucaucgucga ccucggcgcc      780

uaccucgaga aggaguccau cuacuacguc accaccaacu ggaagcacac cgccacccgc      840

uucgccauca agcccaugga ggacugagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9704
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9704
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ugccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgcauccc uuacgaucug ggugccuaug uuccaaucuu caaugccagc cgaucuguug      240

auuaaggaau uagcgaacgu aaauauacug gugaaacaga ucaguacccc gaaggggccc      300

agccuaagag ucaugauuaa cuccaggucu gcugugcucg cccagaugcc uucgaaauuu      360

acaaucugcg caaauguuuc acuggacgag cggagcaaac uugccuauga ugugacuacc      420

ccaugugaaa uuaaggcuug cagucugaca uguuugaagu ccaagaacau gcucaccacu      480

gucaaagacc ugacaaugaa gacccugaau cccacgcaug auaucauagc acucugcgag      540

uucgagaaca ucgugacuuc uaaaaaggua auuaucccua ccuacuuacg cagcauuucc      600

guucgaaaua aggaccugaa cacacuugaa aauaucacua ccacagaguu uaaaaacgcc      660

auaaccaaug cuaagauuau cccauauuca ggauugcugc uagugauuac ggucacugau      720

aacaaaggug ccuucaagua caucaaaccc cagagucaau uuaucgugga ccucggcgcg      780

uaucuggaaa aggagagcau uuacuacgug acaaccaauu ggaaacacac ugcaacacgu      840

uucgccauaa agccuaugga ggauugagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9705
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9705
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac cgccgccgug caguacaacg ugcuggagaa ggacgacgac      180

cccgccagcc ugaccaucug ggugcccaug uuccagagca gcaugcccgc cgaccugcug      240

aucaaggagc uggccaacgu gaacauccug gugaagcaga ucagcacccc caagggcccc      300

agccugagag ugaugaucaa cagcagaagc gccgugcugg cccagaugcc cagcaaguuc      360

accaucugcg ccaacgugag ccuggacgag agaagcaagc uggccuacga cgugaccacc      420

cccugcgaga ucaaggccug cagccugacc ugccugaaga gcaagaacau gcugaccacc      480

gugaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccugugcgag      540

uucgagaaca ucgugaccag caagaaggug aucaucccca ccuaccugag aagcaucagc      600

gugagaaaca aggaccugaa cacccuggag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacagc ggccugcugc uggugaucac cgugaccgac      720

aacaagggcg ccuucaagua caucaagccc cagagccagu ucaucgugga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccaccaga      840

uucgccauca agcccaugga ggacugagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9706
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9706
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ggccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgccuccc ugaccaucug ggugccuaug uuccaaucua gcaugccggc ggaucuucug      240

auuaaggaac ucgcuaacgu gaauauccug gucaaacaga uuuccacacc caaggggccu      300

ucucuuagag ugaugaucaa cagccggucc gccguucugg cccagaugcc cucuaaauuu      360

accauuugcg cuaaugugag ccucgacgag cgcuccaagc uggccuauga ugucacaacc      420

ccuugugaaa ucaaggcuug cagccugaca ugucucaaau cuaagaacau gcugaccacg      480

gugaaagacc uuaccaugaa gacacugaau cccacccaug auaucauugc ccucugcgag      540

uucgagaaca ucguuacauc caaaaaggug auuaucccua ccuaccugag aagcauuucu      600

guccggaaua aggaccuuaa cacgcuggaa aauaucacaa ccacagaguu uaaaaacgcg      660

auuaccaaug ccaagaucau cccguauucc ggacuccugc uggugauuac cgugacagau      720

aacaaaggcg cuuucaagua caucaaaccc cagagccaau uuauugucga ccucggggcc      780

uaucuggaaa aggagucuau cuacuacguu acgaccaauu ggaaacacac agcuacccgc      840

uucgccauua agccuaugga ggauugagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9707
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9707
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu aaacaaacua      120

cacgaaggau ccacauacac agcagcagua caauacaacg uacuagaaaa agacgacgac      180

ccagcaucuu uaaccauaug gguaccaaug uuccaaucau caaugccagc agaccucuua      240

auaaaagaac uagcaaacgu aaacauccua gucaaacaaa uaucaacacc caaaggacca      300

ucccucagag uaaugaucaa cucaagauca gcaguacuag cacaaaugcc aucaaaauuc      360

acaauaugcg ccaacguuuc uuuagacgaa cgaucaaaau uagccuacga cguaacaaca      420

cccugcgaaa uaaaagcaug cucacuaaca ugccuaaaau caaaaaacau gcucacuaca      480

guaaaagacc uaaccaugaa aacacucaac ccaacacacg acauaauagc ccuaugcgaa      540

uuugaaaaca uaguaacauc aaaaaaagua auaaucccaa cauacuuaag aucgaucuca      600

gucagaaaca aagaccuaaa uacacucgaa aacauaacaa caacagaauu uaaaaacgca      660

auaacaaacg caaaaauaau accauacuca ggacuacucc uaguaauaac aguaacagac      720

aacaaaggag cauucaaaua cauaaaacca caaucacaau ucaucguaga ccucggagca      780

uaccuagaaa aagaaucaau auacuacgua acaacaaacu ggaaacacac cgccacaaga      840

uucgcaauaa aacccaugga agacuaagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9708
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9708
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaccuacgu caacaaacua      120

cacgaaggcu caaccuacac cgccgccguc caauacaacg uccucgaaaa agacgacgac      180

cccgccuccc uaaccaucug gguucccaug uuccaaucau ccaugcccgc cgaccuccuc      240

auaaaagaac uagccaacgu caacauccua gucaaacaaa ucagcacccc caaaggcccc      300

ucccuccgcg uaaugaucaa cucccgcucc gccguccuag cccaaaugcc cuccaaauuu      360

acaaucugcg ccaacgucuc ccucgacgaa cgcucaaaac ucgccuacga cgucaccaca      420

cccugcgaaa ucaaagccug cucccucacc ugccucaaaa gcaaaaauau gcuaaccacc      480

gucaaagacc uuaccaugaa aacccucaac cccacucacg acaucauagc ccucugcgaa      540

uuugaaaaca ucgucaccuc caaaaaaguc aucaucccca cauaccuccg cuccaucucc      600

guccgcaaca aagaccucaa cacccucgaa aacaucacca ccaccgaauu uaaaaacgcc      660

aucaccaacg ccaaaaucau ccccuacucc ggccuccucc ucgucaucac cguuaccgac      720

aacaaaggcg ccuucaaaua caucaaaccc caaucccaau ucaucgucga ccucggagcc      780

uaccuugaaa aagaguccau cuacuacguc accaccaacu ggaaacacac cgccacccga      840

uucgccauca aacccaugga agacuaagga cuagucccug uucccagagc ccacuuuuuu      900

uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  9709
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9709
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguga acaagcuuca cgaaggcucc acauacacag cugcuguuca auacaauguc      240

uuagaaaaag acgaugaccc ugcaucacuu acaauauggg ugcccauguu ccaaucaucu      300

augccagcag auuuacuuau aaaagaacua gcuaauguca acauacuagu gaaacaaaua      360

uccacaccca agggaccuuc acuaagaguc augauaaacu caagaagugc agugcuagca      420

caaaugccca gcaaauuuac cauaugcgcu aauguguccu uggaugaaag aagcaaacua      480

gcauaugaug uaaccacacc cugugaaauc aaggcaugua gucuaacaug ccuaaaauca      540

aaaaauaugu ugacuacagu uaaagaucuc acuaugaaga cacucaaccc uacacaugau      600

auuauugcuu uaugugaauu ugaaaacaua guaacaucaa aaaaagucau aauaccaaca      660

uaccuaagau ccaucagugu cagaaauaaa gaucugaaca cacuugaaaa uauaacaacc      720

acugaauuca aaaaugcuau cacaaaugca aaaaucaucc cuuacucagg auuacuauua      780

gucaucacag ugacugacaa caaaggagca uucaaauaca uaaagccaca aagucaauuc      840

auaguagauc uuggagcuua ccuagaaaaa gaaaguauau auuauguuac cacaaauugg      900

aagcacacag cuacacgauu ugcaaucaaa cccauggaag auuaaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9710
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9710
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacacgg ccgccgucca guacaacgug      240

cucgagaagg acgacgaccc cgcgucccug accaucuggg ugccgauguu ccagagcucc      300

augcccgccg accugcucau caaggagcug gccaacguca acauccuggu gaagcagauc      360

agcaccccca aggggcccuc ccuccgcgug augaucaaca gccgguccgc cguccuggcc      420

cagaugccga gcaaguucac caucugcgcg aacguguccc uggacgagcg cagcaagcuc      480

gccuacgacg ugacgacccc cugcgagauc aaggccugcu cccugaccug ccucaagagc      540

aagaacaugc ugaccacggu caaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gugacgucca agaaggugau cauccccacc      660

uaccugcgga gcaucuccgu ccgcaacaag gaccugaaca cccucgagaa caucaccacg      720

accgaguuca agaacgcgau caccaacgcc aagaucaucc cguacagcgg ccugcugcuc      780

gugaucaccg ugacggacaa caagggggcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccacgcgguu cgcgaucaag cccauggagg acugaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9711
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9711
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguca acaagcucca cgagggcucc accuacaccg ccgccgucca guacaacguc      240

cucgagaagg acgacgaccc cgccucccuc accaucuggg uccccauguu ccaguccucc      300

augcccgccg accuccucau caaggagcuc gccaacguca acauccucgu caagcagauc      360

uccaccccca agggccccuc ccuccgcguc augaucaacu cccgcuccgc cguccucgcc      420

cagaugcccu ccaaguucac caucugcgcc aacgucuccc ucgacgagcg cuccaagcuc      480

gccuacgacg ucaccacccc cugcgagauc aaggccugcu cccucaccug ccucaagucc      540

aagaacaugc ucaccaccgu caaggaccuc accaugaaga cccucaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gucaccucca agaaggucau cauccccacc      660

uaccuccgcu ccaucuccgu ccgcaacaag gaccucaaca cccucgagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg ucaccgacaa caagggcgcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ucggcgccua ccucgagaag gaguccaucu acuacgucac caccaacugg      900

aagcacaccg ccacccgcuu cgccaucaag cccauggagg acugaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9712
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9712
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacug ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgcaucccuu acgaucuggg ugccuauguu ccaaucuuca      300

augccagccg aucuguugau uaaggaauua gcgaacguaa auauacuggu gaaacagauc      360

aguaccccga aggggcccag ccuaagaguc augauuaacu ccaggucugc ugugcucgcc      420

cagaugccuu cgaaauuuac aaucugcgca aauguuucac uggacgagcg gagcaaacuu      480

gccuaugaug ugacuacccc augugaaauu aaggcuugca gucugacaug uuugaagucc      540

aagaacaugc ucaccacugu caaagaccug acaaugaaga cccugaaucc cacgcaugau      600

aucauagcac ucugcgaguu cgagaacauc gugacuucua aaaagguaau uaucccuacc      660

uacuuacgca gcauuuccgu ucgaaauaag gaccugaaca cacuugaaaa uaucacuacc      720

acagaguuua aaaacgccau aaccaaugcu aagauuaucc cauauucagg auugcugcua      780

gugauuacgg ucacugauaa caaaggugcc uucaaguaca ucaaacccca gagucaauuu      840

aucguggacc ucggcgcgua ucuggaaaag gagagcauuu acuacgugac aaccaauugg      900

aaacacacug caacacguuu cgccauaaag ccuauggagg auugaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9713
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9713
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacaccg ccgccgugca guacaacgug      240

cuggagaagg acgacgaccc cgccagccug accaucuggg ugcccauguu ccagagcagc      300

augcccgccg accugcugau caaggagcug gccaacguga acauccuggu gaagcagauc      360

agcaccccca agggccccag ccugagagug augaucaaca gcagaagcgc cgugcuggcc      420

cagaugccca gcaaguucac caucugcgcc aacgugagcc uggacgagag aagcaagcug      480

gccuacgacg ugaccacccc cugcgagauc aaggccugca gccugaccug ccugaagagc      540

aagaacaugc ugaccaccgu gaaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ugugcgaguu cgagaacauc gugaccagca agaaggugau cauccccacc      660

uaccugagaa gcaucagcgu gagaaacaag gaccugaaca cccuggagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacagcgg ccugcugcug      780

gugaucaccg ugaccgacaa caagggcgcc uucaaguaca ucaagcccca gagccaguuc      840

aucguggacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccaccagauu cgccaucaag cccauggagg acugaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9714
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9714
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacgg ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgccucccug accaucuggg ugccuauguu ccaaucuagc      300

augccggcgg aucuucugau uaaggaacuc gcuaacguga auauccuggu caaacagauu      360

uccacaccca aggggccuuc ucuuagagug augaucaaca gccgguccgc cguucuggcc      420

cagaugcccu cuaaauuuac cauuugcgcu aaugugagcc ucgacgagcg cuccaagcug      480

gccuaugaug ucacaacccc uugugaaauc aaggcuugca gccugacaug ucucaaaucu      540

aagaacaugc ugaccacggu gaaagaccuu accaugaaga cacugaaucc cacccaugau      600

aucauugccc ucugcgaguu cgagaacauc guuacaucca aaaaggugau uaucccuacc      660

uaccugagaa gcauuucugu ccggaauaag gaccuuaaca cgcuggaaaa uaucacaacc      720

acagaguuua aaaacgcgau uaccaaugcc aagaucaucc cguauuccgg acuccugcug      780

gugauuaccg ugacagauaa caaaggcgcu uucaaguaca ucaaacccca gagccaauuu      840

auugucgacc ucggggccua ucuggaaaag gagucuaucu acuacguuac gaccaauugg      900

aaacacacag cuacccgcuu cgccauuaag ccuauggagg auugaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9715
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9715
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguaa acaaacuaca cgaaggaucc acauacacag cagcaguaca auacaacgua      240

cuagaaaaag acgacgaccc agcaucuuua accauauggg uaccaauguu ccaaucauca      300

augccagcag accucuuaau aaaagaacua gcaaacguaa acauccuagu caaacaaaua      360

ucaacaccca aaggaccauc ccucagagua augaucaacu caagaucagc aguacuagca      420

caaaugccau caaaauucac aauaugcgcc aacguuucuu uagacgaacg aucaaaauua      480

gccuacgacg uaacaacacc cugcgaaaua aaagcaugcu cacuaacaug ccuaaaauca      540

aaaaacaugc ucacuacagu aaaagaccua accaugaaaa cacucaaccc aacacacgac      600

auaauagccc uaugcgaauu ugaaaacaua guaacaucaa aaaaaguaau aaucccaaca      660

uacuuaagau cgaucucagu cagaaacaaa gaccuaaaua cacucgaaaa cauaacaaca      720

acagaauuua aaaacgcaau aacaaacgca aaaauaauac cauacucagg acuacuccua      780

guaauaacag uaacagacaa caaaggagca uucaaauaca uaaaaccaca aucacaauuc      840

aucguagacc ucggagcaua ccuagaaaaa gaaucaauau acuacguaac aacaaacugg      900

aaacacaccg ccacaagauu cgcaauaaaa cccauggaag acuaaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9716
<211>  1144
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9716
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

accuacguca acaaacuaca cgaaggcuca accuacaccg ccgccgucca auacaacguc      240

cucgaaaaag acgacgaccc cgccucccua accaucuggg uucccauguu ccaaucaucc      300

augcccgccg accuccucau aaaagaacua gccaacguca acauccuagu caaacaaauc      360

agcaccccca aaggccccuc ccuccgcgua augaucaacu cccgcuccgc cguccuagcc      420

caaaugcccu ccaaauuuac aaucugcgcc aacgucuccc ucgacgaacg cucaaaacuc      480

gccuacgacg ucaccacacc cugcgaaauc aaagccugcu cccucaccug ccucaaaagc      540

aaaaauaugc uaaccaccgu caaagaccuu accaugaaaa cccucaaccc cacucacgac      600

aucauagccc ucugcgaauu ugaaaacauc gucaccucca aaaaagucau cauccccaca      660

uaccuccgcu ccaucuccgu ccgcaacaaa gaccucaaca cccucgaaaa caucaccacc      720

accgaauuua aaaacgccau caccaacgcc aaaaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg uuaccgacaa caaaggcgcc uucaaauaca ucaaacccca aucccaauuc      840

aucgucgacc ucggagccua ccuugaaaaa gaguccaucu acuacgucac caccaacugg      900

aaacacaccg ccacccgauu cgccaucaaa cccauggaag acuaaggacu agucccuguu      960

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1140

aauu                                                                  1144


<210>  9717
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9717
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacgugaa caagcuucac gaaggcucca cauacacagc ugcuguucaa      180

uacaaugucu uagaaaaaga cgaugacccu gcaucacuua caauaugggu gcccauguuc      240

caaucaucua ugccagcaga uuuacuuaua aaagaacuag cuaaugucaa cauacuagug      300

aaacaaauau ccacacccaa gggaccuuca cuaagaguca ugauaaacuc aagaagugca      360

gugcuagcac aaaugcccag caaauuuacc auaugcgcua auguguccuu ggaugaaaga      420

agcaaacuag cauaugaugu aaccacaccc ugugaaauca aggcauguag ucuaacaugc      480

cuaaaaucaa aaaauauguu gacuacaguu aaagaucuca cuaugaagac acucaacccu      540

acacaugaua uuauugcuuu augugaauuu gaaaacauag uaacaucaaa aaaagucaua      600

auaccaacau accuaagauc caucaguguc agaaauaaag aucugaacac acuugaaaau      660

auaacaacca cugaauucaa aaaugcuauc acaaaugcaa aaaucauccc uuacucagga      720

uuacuauuag ucaucacagu gacugacaac aaaggagcau ucaaauacau aaagccacaa      780

agucaauuca uaguagaucu uggagcuuac cuagaaaaag aaaguauaua uuauguuacc      840

acaaauugga agcacacagc uacacgauuu gcaaucaaac ccauggaaga uuaaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9718
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9718
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacacggc cgccguccag      180

uacaacgugc ucgagaagga cgacgacccc gcgucccuga ccaucugggu gccgauguuc      240

cagagcucca ugcccgccga ccugcucauc aaggagcugg ccaacgucaa cauccuggug      300

aagcagauca gcacccccaa ggggcccucc cuccgcguga ugaucaacag ccgguccgcc      360

guccuggccc agaugccgag caaguucacc aucugcgcga acgugucccu ggacgagcgc      420

agcaagcucg ccuacgacgu gacgaccccc ugcgagauca aggccugcuc ccugaccugc      480

cucaagagca agaacaugcu gaccacgguc aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ugacguccaa gaaggugauc      600

auccccaccu accugcggag caucuccguc cgcaacaagg accugaacac ccucgagaac      660

aucaccacga ccgaguucaa gaacgcgauc accaacgcca agaucauccc guacagcggc      720

cugcugcucg ugaucaccgu gacggacaac aagggggccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc cacgcgguuc gcgaucaagc ccauggagga cugaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9719
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9719
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgucaa caagcuccac gagggcucca ccuacaccgc cgccguccag      180

uacaacgucc ucgagaagga cgacgacccc gccucccuca ccaucugggu ccccauguuc      240

caguccucca ugcccgccga ccuccucauc aaggagcucg ccaacgucaa cauccucguc      300

aagcagaucu ccacccccaa gggccccucc cuccgcguca ugaucaacuc ccgcuccgcc      360

guccucgccc agaugcccuc caaguucacc aucugcgcca acgucucccu cgacgagcgc      420

uccaagcucg ccuacgacgu caccaccccc ugcgagauca aggccugcuc ccucaccugc      480

cucaagucca agaacaugcu caccaccguc aaggaccuca ccaugaagac ccucaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ucaccuccaa gaaggucauc      600

auccccaccu accuccgcuc caucuccguc cgcaacaagg accucaacac ccucgagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu caccgacaac aagggcgccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu cggcgccuac cucgagaagg aguccaucua cuacgucacc      840

accaacugga agcacaccgc cacccgcuuc gccaucaagc ccauggagga cugaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9720
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9720
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacugc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gcaucccuua cgaucugggu gccuauguuc      240

caaucuucaa ugccagccga ucuguugauu aaggaauuag cgaacguaaa uauacuggug      300

aaacagauca guaccccgaa ggggcccagc cuaagaguca ugauuaacuc caggucugcu      360

gugcucgccc agaugccuuc gaaauuuaca aucugcgcaa auguuucacu ggacgagcgg      420

agcaaacuug ccuaugaugu gacuacccca ugugaaauua aggcuugcag ucugacaugu      480

uugaagucca agaacaugcu caccacuguc aaagaccuga caaugaagac ccugaauccc      540

acgcaugaua ucauagcacu cugcgaguuc gagaacaucg ugacuucuaa aaagguaauu      600

aucccuaccu acuuacgcag cauuuccguu cgaaauaagg accugaacac acuugaaaau      660

aucacuacca cagaguuuaa aaacgccaua accaaugcua agauuauccc auauucagga      720

uugcugcuag ugauuacggu cacugauaac aaaggugccu ucaaguacau caaaccccag      780

agucaauuua ucguggaccu cggcgcguau cuggaaaagg agagcauuua cuacgugaca      840

accaauugga aacacacugc aacacguuuc gccauaaagc cuauggagga uugaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9721
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9721
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacaccgc cgccgugcag      180

uacaacgugc uggagaagga cgacgacccc gccagccuga ccaucugggu gcccauguuc      240

cagagcagca ugcccgccga ccugcugauc aaggagcugg ccaacgugaa cauccuggug      300

aagcagauca gcacccccaa gggccccagc cugagaguga ugaucaacag cagaagcgcc      360

gugcuggccc agaugcccag caaguucacc aucugcgcca acgugagccu ggacgagaga      420

agcaagcugg ccuacgacgu gaccaccccc ugcgagauca aggccugcag ccugaccugc      480

cugaagagca agaacaugcu gaccaccgug aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu gugcgaguuc gagaacaucg ugaccagcaa gaaggugauc      600

auccccaccu accugagaag caucagcgug agaaacaagg accugaacac ccuggagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacagcggc      720

cugcugcugg ugaucaccgu gaccgacaac aagggcgccu ucaaguacau caagccccag      780

agccaguuca ucguggaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc caccagauuc gccaucaagc ccauggagga cugaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9722
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9722
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacggc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gccucccuga ccaucugggu gccuauguuc      240

caaucuagca ugccggcgga ucuucugauu aaggaacucg cuaacgugaa uauccugguc      300

aaacagauuu ccacacccaa ggggccuucu cuuagaguga ugaucaacag ccgguccgcc      360

guucuggccc agaugcccuc uaaauuuacc auuugcgcua augugagccu cgacgagcgc      420

uccaagcugg ccuaugaugu cacaaccccu ugugaaauca aggcuugcag ccugacaugu      480

cucaaaucua agaacaugcu gaccacggug aaagaccuua ccaugaagac acugaauccc      540

acccaugaua ucauugcccu cugcgaguuc gagaacaucg uuacauccaa aaaggugauu      600

aucccuaccu accugagaag cauuucuguc cggaauaagg accuuaacac gcuggaaaau      660

aucacaacca cagaguuuaa aaacgcgauu accaaugcca agaucauccc guauuccgga      720

cuccugcugg ugauuaccgu gacagauaac aaaggcgcuu ucaaguacau caaaccccag      780

agccaauuua uugucgaccu cggggccuau cuggaaaagg agucuaucua cuacguuacg      840

accaauugga aacacacagc uacccgcuuc gccauuaagc cuauggagga uugaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9723
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9723
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacguaaa caaacuacac gaaggaucca cauacacagc agcaguacaa      180

uacaacguac uagaaaaaga cgacgaccca gcaucuuuaa ccauaugggu accaauguuc      240

caaucaucaa ugccagcaga ccucuuaaua aaagaacuag caaacguaaa cauccuaguc      300

aaacaaauau caacacccaa aggaccaucc cucagaguaa ugaucaacuc aagaucagca      360

guacuagcac aaaugccauc aaaauucaca auaugcgcca acguuucuuu agacgaacga      420

ucaaaauuag ccuacgacgu aacaacaccc ugcgaaauaa aagcaugcuc acuaacaugc      480

cuaaaaucaa aaaacaugcu cacuacagua aaagaccuaa ccaugaaaac acucaaccca      540

acacacgaca uaauagcccu augcgaauuu gaaaacauag uaacaucaaa aaaaguaaua      600

aucccaacau acuuaagauc gaucucaguc agaaacaaag accuaaauac acucgaaaac      660

auaacaacaa cagaauuuaa aaacgcaaua acaaacgcaa aaauaauacc auacucagga      720

cuacuccuag uaauaacagu aacagacaac aaaggagcau ucaaauacau aaaaccacaa      780

ucacaauuca ucguagaccu cggagcauac cuagaaaaag aaucaauaua cuacguaaca      840

acaaacugga aacacaccgc cacaagauuc gcaauaaaac ccauggaaga cuaaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9724
<211>  1093
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9724
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa ccuacgucaa caaacuacac gaaggcucaa ccuacaccgc cgccguccaa      180

uacaacgucc ucgaaaaaga cgacgacccc gccucccuaa ccaucugggu ucccauguuc      240

caaucaucca ugcccgccga ccuccucaua aaagaacuag ccaacgucaa cauccuaguc      300

aaacaaauca gcacccccaa aggccccucc cuccgcguaa ugaucaacuc ccgcuccgcc      360

guccuagccc aaaugcccuc caaauuuaca aucugcgcca acgucucccu cgacgaacgc      420

ucaaaacucg ccuacgacgu caccacaccc ugcgaaauca aagccugcuc ccucaccugc      480

cucaaaagca aaaauaugcu aaccaccguc aaagaccuua ccaugaaaac ccucaacccc      540

acucacgaca ucauagcccu cugcgaauuu gaaaacaucg ucaccuccaa aaaagucauc      600

auccccacau accuccgcuc caucuccguc cgcaacaaag accucaacac ccucgaaaac      660

aucaccacca ccgaauuuaa aaacgccauc accaacgcca aaaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu uaccgacaac aaaggcgccu ucaaauacau caaaccccaa      780

ucccaauuca ucgucgaccu cggagccuac cuugaaaaag aguccaucua cuacgucacc      840

accaacugga aacacaccgc cacccgauuc gccaucaaac ccauggaaga cuaaggacua      900

gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca      960

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1080

agccaccaga auu                                                        1093


<210>  9725
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9725
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cgugaacaag cuucacgaag gcuccacaua cacagcugcu      120

guucaauaca augucuuaga aaaagacgau gacccugcau cacuuacaau augggugccc      180

auguuccaau caucuaugcc agcagauuua cuuauaaaag aacuagcuaa ugucaacaua      240

cuagugaaac aaauauccac acccaaggga ccuucacuaa gagucaugau aaacucaaga      300

agugcagugc uagcacaaau gcccagcaaa uuuaccauau gcgcuaaugu guccuuggau      360

gaaagaagca aacuagcaua ugauguaacc acacccugug aaaucaaggc auguagucua      420

acaugccuaa aaucaaaaaa uauguugacu acaguuaaag aucucacuau gaagacacuc      480

aacccuacac augauauuau ugcuuuaugu gaauuugaaa acauaguaac aucaaaaaaa      540

gucauaauac caacauaccu aagauccauc agugucagaa auaaagaucu gaacacacuu      600

gaaaauauaa caaccacuga auucaaaaau gcuaucacaa augcaaaaau caucccuuac      660

ucaggauuac uauuagucau cacagugacu gacaacaaag gagcauucaa auacauaaag      720

ccacaaaguc aauucauagu agaucuugga gcuuaccuag aaaaagaaag uauauauuau      780

guuaccacaa auuggaagca cacagcuaca cgauuugcaa ucaaacccau ggaagauuaa      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9726
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9726
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua cacggccgcc      120

guccaguaca acgugcucga gaaggacgac gaccccgcgu cccugaccau cugggugccg      180

auguuccaga gcuccaugcc cgccgaccug cucaucaagg agcuggccaa cgucaacauc      240

cuggugaagc agaucagcac ccccaagggg cccucccucc gcgugaugau caacagccgg      300

uccgccgucc uggcccagau gccgagcaag uucaccaucu gcgcgaacgu gucccuggac      360

gagcgcagca agcucgccua cgacgugacg acccccugcg agaucaaggc cugcucccug      420

accugccuca agagcaagaa caugcugacc acggucaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgugac guccaagaag      540

gugaucaucc ccaccuaccu gcggagcauc uccguccgca acaaggaccu gaacacccuc      600

gagaacauca ccacgaccga guucaagaac gcgaucacca acgccaagau caucccguac      660

agcggccugc ugcucgugau caccgugacg gacaacaagg gggccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacg cgguucgcga ucaagcccau ggaggacuga      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9727
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9727
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgucaacaag cuccacgagg gcuccaccua caccgccgcc      120

guccaguaca acguccucga gaaggacgac gaccccgccu cccucaccau cugggucccc      180

auguuccagu ccuccaugcc cgccgaccuc cucaucaagg agcucgccaa cgucaacauc      240

cucgucaagc agaucuccac ccccaagggc cccucccucc gcgucaugau caacucccgc      300

uccgccgucc ucgcccagau gcccuccaag uucaccaucu gcgccaacgu cucccucgac      360

gagcgcucca agcucgccua cgacgucacc acccccugcg agaucaaggc cugcucccuc      420

accugccuca aguccaagaa caugcucacc accgucaagg accucaccau gaagacccuc      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgucac cuccaagaag      540

gucaucaucc ccaccuaccu ccgcuccauc uccguccgca acaaggaccu caacacccuc      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

uccggccucc uccucgucau caccgucacc gacaacaagg gcgccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccucggc gccuaccucg agaaggaguc caucuacuac      780

gucaccacca acuggaagca caccgccacc cgcuucgcca ucaagcccau ggaggacuga      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9728
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9728
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacugccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgcau cccuuacgau cugggugccu      180

auguuccaau cuucaaugcc agccgaucug uugauuaagg aauuagcgaa cguaaauaua      240

cuggugaaac agaucaguac cccgaagggg cccagccuaa gagucaugau uaacuccagg      300

ucugcugugc ucgcccagau gccuucgaaa uuuacaaucu gcgcaaaugu uucacuggac      360

gagcggagca aacuugccua ugaugugacu accccaugug aaauuaaggc uugcagucug      420

acauguuuga aguccaagaa caugcucacc acugucaaag accugacaau gaagacccug      480

aaucccacgc augauaucau agcacucugc gaguucgaga acaucgugac uucuaaaaag      540

guaauuaucc cuaccuacuu acgcagcauu uccguucgaa auaaggaccu gaacacacuu      600

gaaaauauca cuaccacaga guuuaaaaac gccauaacca augcuaagau uaucccauau      660

ucaggauugc ugcuagugau uacggucacu gauaacaaag gugccuucaa guacaucaaa      720

ccccagaguc aauuuaucgu ggaccucggc gcguaucugg aaaaggagag cauuuacuac      780

gugacaacca auuggaaaca cacugcaaca cguuucgcca uaaagccuau ggaggauuga      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9729
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9729
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua caccgccgcc      120

gugcaguaca acgugcugga gaaggacgac gaccccgcca gccugaccau cugggugccc      180

auguuccaga gcagcaugcc cgccgaccug cugaucaagg agcuggccaa cgugaacauc      240

cuggugaagc agaucagcac ccccaagggc cccagccuga gagugaugau caacagcaga      300

agcgccgugc uggcccagau gcccagcaag uucaccaucu gcgccaacgu gagccuggac      360

gagagaagca agcuggccua cgacgugacc acccccugcg agaucaaggc cugcagccug      420

accugccuga agagcaagaa caugcugacc accgugaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccugugc gaguucgaga acaucgugac cagcaagaag      540

gugaucaucc ccaccuaccu gagaagcauc agcgugagaa acaaggaccu gaacacccug      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

agcggccugc ugcuggugau caccgugacc gacaacaagg gcgccuucaa guacaucaag      720

ccccagagcc aguucaucgu ggaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacc agauucgcca ucaagcccau ggaggacuga      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9730
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9730
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacggccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgccu cccugaccau cugggugccu      180

auguuccaau cuagcaugcc ggcggaucuu cugauuaagg aacucgcuaa cgugaauauc      240

cuggucaaac agauuuccac acccaagggg ccuucucuua gagugaugau caacagccgg      300

uccgccguuc uggcccagau gcccucuaaa uuuaccauuu gcgcuaaugu gagccucgac      360

gagcgcucca agcuggccua ugaugucaca accccuugug aaaucaaggc uugcagccug      420

acaugucuca aaucuaagaa caugcugacc acggugaaag accuuaccau gaagacacug      480

aaucccaccc augauaucau ugcccucugc gaguucgaga acaucguuac auccaaaaag      540

gugauuaucc cuaccuaccu gagaagcauu ucuguccgga auaaggaccu uaacacgcug      600

gaaaauauca caaccacaga guuuaaaaac gcgauuacca augccaagau caucccguau      660

uccggacucc ugcuggugau uaccgugaca gauaacaaag gcgcuuucaa guacaucaaa      720

ccccagagcc aauuuauugu cgaccucggg gccuaucugg aaaaggaguc uaucuacuac      780

guuacgacca auuggaaaca cacagcuacc cgcuucgcca uuaagccuau ggaggauuga      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9731
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9731
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cguaaacaaa cuacacgaag gauccacaua cacagcagca      120

guacaauaca acguacuaga aaaagacgac gacccagcau cuuuaaccau auggguacca      180

auguuccaau caucaaugcc agcagaccuc uuaauaaaag aacuagcaaa cguaaacauc      240

cuagucaaac aaauaucaac acccaaagga ccaucccuca gaguaaugau caacucaaga      300

ucagcaguac uagcacaaau gccaucaaaa uucacaauau gcgccaacgu uucuuuagac      360

gaacgaucaa aauuagccua cgacguaaca acacccugcg aaauaaaagc augcucacua      420

acaugccuaa aaucaaaaaa caugcucacu acaguaaaag accuaaccau gaaaacacuc      480

aacccaacac acgacauaau agcccuaugc gaauuugaaa acauaguaac aucaaaaaaa      540

guaauaaucc caacauacuu aagaucgauc ucagucagaa acaaagaccu aaauacacuc      600

gaaaacauaa caacaacaga auuuaaaaac gcaauaacaa acgcaaaaau aauaccauac      660

ucaggacuac uccuaguaau aacaguaaca gacaacaaag gagcauucaa auacauaaaa      720

ccacaaucac aauucaucgu agaccucgga gcauaccuag aaaaagaauc aauauacuac      780

guaacaacaa acuggaaaca caccgccaca agauucgcaa uaaaacccau ggaagacuaa      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9732
<211>  1039
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9732
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaccua cgucaacaaa cuacacgaag gcucaaccua caccgccgcc      120

guccaauaca acguccucga aaaagacgac gaccccgccu cccuaaccau cuggguuccc      180

auguuccaau cauccaugcc cgccgaccuc cucauaaaag aacuagccaa cgucaacauc      240

cuagucaaac aaaucagcac ccccaaaggc cccucccucc gcguaaugau caacucccgc      300

uccgccgucc uagcccaaau gcccuccaaa uuuacaaucu gcgccaacgu cucccucgac      360

gaacgcucaa aacucgccua cgacgucacc acacccugcg aaaucaaagc cugcucccuc      420

accugccuca aaagcaaaaa uaugcuaacc accgucaaag accuuaccau gaaaacccuc      480

aaccccacuc acgacaucau agcccucugc gaauuugaaa acaucgucac cuccaaaaaa      540

gucaucaucc ccacauaccu ccgcuccauc uccguccgca acaaagaccu caacacccuc      600

gaaaacauca ccaccaccga auuuaaaaac gccaucacca acgccaaaau cauccccuac      660

uccggccucc uccucgucau caccguuacc gacaacaaag gcgccuucaa auacaucaaa      720

ccccaauccc aauucaucgu cgaccucgga gccuaccuug aaaaagaguc caucuacuac      780

gucaccacca acuggaaaca caccgccacc cgauucgcca ucaaacccau ggaagacuaa      840

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      900

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1020

uuucagagcc accagaauu                                                  1039


<210>  9733
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9733
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaaacauacg ugaacaagcu ucacgaaggc uccacauaca cagcugcugu ucaauacaau      300

gucuuagaaa aagacgauga cccugcauca cuuacaauau gggugcccau guuccaauca      360

ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug ucaacauacu agugaaacaa      420

auauccacac ccaagggacc uucacuaaga gucaugauaa acucaagaag ugcagugcua      480

gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu ccuuggauga aagaagcaaa      540

cuagcauaug auguaaccac acccugugaa aucaaggcau guagucuaac augccuaaaa      600

ucaaaaaaua uguugacuac aguuaaagau cucacuauga agacacucaa cccuacacau      660

gauauuauug cuuuauguga auuugaaaac auaguaacau caaaaaaagu cauaauacca      720

acauaccuaa gauccaucag ugucagaaau aaagaucuga acacacuuga aaauauaaca      780

accacugaau ucaaaaaugc uaucacaaau gcaaaaauca ucccuuacuc aggauuacua      840

uuagucauca cagugacuga caacaaagga gcauucaaau acauaaagcc acaaagucaa      900

uucauaguag aucuuggagc uuaccuagaa aaagaaagua uauauuaugu uaccacaaau      960

uggaagcaca cagcuacacg auuugcaauc aaacccaugg aagauuaagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9734
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9734
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca cggccgccgu ccaguacaac      300

gugcucgaga aggacgacga ccccgcgucc cugaccaucu gggugccgau guuccagagc      360

uccaugcccg ccgaccugcu caucaaggag cuggccaacg ucaacauccu ggugaagcag      420

aucagcaccc ccaaggggcc cucccuccgc gugaugauca acagccgguc cgccguccug      480

gcccagaugc cgagcaaguu caccaucugc gcgaacgugu cccuggacga gcgcagcaag      540

cucgccuacg acgugacgac ccccugcgag aucaaggccu gcucccugac cugccucaag      600

agcaagaaca ugcugaccac ggucaaggac cugaccauga agacccugaa ccccacccac      660

gacaucaucg cccucugcga guucgagaac aucgugacgu ccaagaaggu gaucaucccc      720

accuaccugc ggagcaucuc cguccgcaac aaggaccuga acacccucga gaacaucacc      780

acgaccgagu ucaagaacgc gaucaccaac gccaagauca ucccguacag cggccugcug      840

cucgugauca ccgugacgga caacaagggg gccuucaagu acaucaagcc ccagucccag      900

uucaucgucg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      960

uggaagcaca ccgccacgcg guucgcgauc aagcccaugg aggacugagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9735
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9735
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaccuacg ucaacaagcu ccacgagggc uccaccuaca ccgccgccgu ccaguacaac      300

guccucgaga aggacgacga ccccgccucc cucaccaucu ggguccccau guuccagucc      360

uccaugcccg ccgaccuccu caucaaggag cucgccaacg ucaacauccu cgucaagcag      420

aucuccaccc ccaagggccc cucccuccgc gucaugauca acucccgcuc cgccguccuc      480

gcccagaugc ccuccaaguu caccaucugc gccaacgucu cccucgacga gcgcuccaag      540

cucgccuacg acgucaccac ccccugcgag aucaaggccu gcucccucac cugccucaag      600

uccaagaaca ugcucaccac cgucaaggac cucaccauga agacccucaa ccccacccac      660

gacaucaucg cccucugcga guucgagaac aucgucaccu ccaagaaggu caucaucccc      720

accuaccucc gcuccaucuc cguccgcaac aaggaccuca acacccucga gaacaucacc      780

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacuc cggccuccuc      840

cucgucauca ccgucaccga caacaagggc gccuucaagu acaucaagcc ccagucccag      900

uucaucgucg accucggcgc cuaccucgag aaggagucca ucuacuacgu caccaccaac      960

uggaagcaca ccgccacccg cuucgccauc aagcccaugg aggacugagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9736
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9736
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cugccgcugu ccaguacaau      300

guucucgaga aagacgauga ccccgcaucc cuuacgaucu gggugccuau guuccaaucu      360

ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg uaaauauacu ggugaaacag      420

aucaguaccc cgaaggggcc cagccuaaga gucaugauua acuccagguc ugcugugcuc      480

gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu cacuggacga gcggagcaaa      540

cuugccuaug augugacuac cccaugugaa auuaaggcuu gcagucugac auguuugaag      600

uccaagaaca ugcucaccac ugucaaagac cugacaauga agacccugaa ucccacgcau      660

gauaucauag cacucugcga guucgagaac aucgugacuu cuaaaaaggu aauuaucccu      720

accuacuuac gcagcauuuc cguucgaaau aaggaccuga acacacuuga aaauaucacu      780

accacagagu uuaaaaacgc cauaaccaau gcuaagauua ucccauauuc aggauugcug      840

cuagugauua cggucacuga uaacaaaggu gccuucaagu acaucaaacc ccagagucaa      900

uuuaucgugg accucggcgc guaucuggaa aaggagagca uuuacuacgu gacaaccaau      960

uggaaacaca cugcaacacg uuucgccaua aagccuaugg aggauugagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9737
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9737
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca ccgccgccgu gcaguacaac      300

gugcuggaga aggacgacga ccccgccagc cugaccaucu gggugcccau guuccagagc      360

agcaugcccg ccgaccugcu gaucaaggag cuggccaacg ugaacauccu ggugaagcag      420

aucagcaccc ccaagggccc cagccugaga gugaugauca acagcagaag cgccgugcug      480

gcccagaugc ccagcaaguu caccaucugc gccaacguga gccuggacga gagaagcaag      540

cuggccuacg acgugaccac ccccugcgag aucaaggccu gcagccugac cugccugaag      600

agcaagaaca ugcugaccac cgugaaggac cugaccauga agacccugaa ccccacccac      660

gacaucaucg cccugugcga guucgagaac aucgugacca gcaagaaggu gaucaucccc      720

accuaccuga gaagcaucag cgugagaaac aaggaccuga acacccugga gaacaucacc      780

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacag cggccugcug      840

cuggugauca ccgugaccga caacaagggc gccuucaagu acaucaagcc ccagagccag      900

uucaucgugg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      960

uggaagcaca ccgccaccag auucgccauc aagcccaugg aggacugagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9738
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9738
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cggccgcugu ccaguacaau      300

guucucgaga aagacgauga ccccgccucc cugaccaucu gggugccuau guuccaaucu      360

agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg ugaauauccu ggucaaacag      420

auuuccacac ccaaggggcc uucucuuaga gugaugauca acagccgguc cgccguucug      480

gcccagaugc ccucuaaauu uaccauuugc gcuaauguga gccucgacga gcgcuccaag      540

cuggccuaug augucacaac cccuugugaa aucaaggcuu gcagccugac augucucaaa      600

ucuaagaaca ugcugaccac ggugaaagac cuuaccauga agacacugaa ucccacccau      660

gauaucauug cccucugcga guucgagaac aucguuacau ccaaaaaggu gauuaucccu      720

accuaccuga gaagcauuuc uguccggaau aaggaccuua acacgcugga aaauaucaca      780

accacagagu uuaaaaacgc gauuaccaau gccaagauca ucccguauuc cggacuccug      840

cuggugauua ccgugacaga uaacaaaggc gcuuucaagu acaucaaacc ccagagccaa      900

uuuauugucg accucggggc cuaucuggaa aaggagucua ucuacuacgu uacgaccaau      960

uggaaacaca cagcuacccg cuucgccauu aagccuaugg aggauugagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9739
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9739
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaaacauacg uaaacaaacu acacgaagga uccacauaca cagcagcagu acaauacaac      300

guacuagaaa aagacgacga cccagcaucu uuaaccauau ggguaccaau guuccaauca      360

ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg uaaacauccu agucaaacaa      420

auaucaacac ccaaaggacc aucccucaga guaaugauca acucaagauc agcaguacua      480

gcacaaaugc caucaaaauu cacaauaugc gccaacguuu cuuuagacga acgaucaaaa      540

uuagccuacg acguaacaac acccugcgaa auaaaagcau gcucacuaac augccuaaaa      600

ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga aaacacucaa cccaacacac      660

gacauaauag cccuaugcga auuugaaaac auaguaacau caaaaaaagu aauaauccca      720

acauacuuaa gaucgaucuc agucagaaac aaagaccuaa auacacucga aaacauaaca      780

acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa uaccauacuc aggacuacuc      840

cuaguaauaa caguaacaga caacaaagga gcauucaaau acauaaaacc acaaucacaa      900

uucaucguag accucggagc auaccuagaa aaagaaucaa uauacuacgu aacaacaaac      960

uggaaacaca ccgccacaag auucgcaaua aaacccaugg aagacuaagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9740
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9740
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca ccgccgccgu ccaauacaac      300

guccucgaaa aagacgacga ccccgccucc cuaaccaucu ggguucccau guuccaauca      360

uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg ucaacauccu agucaaacaa      420

aucagcaccc ccaaaggccc cucccuccgc guaaugauca acucccgcuc cgccguccua      480

gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu cccucgacga acgcucaaaa      540

cucgccuacg acgucaccac acccugcgaa aucaaagccu gcucccucac cugccucaaa      600

agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga aaacccucaa ccccacucac      660

gacaucauag cccucugcga auuugaaaac aucgucaccu ccaaaaaagu caucaucccc      720

acauaccucc gcuccaucuc cguccgcaac aaagaccuca acacccucga aaacaucacc      780

accaccgaau uuaaaaacgc caucaccaac gccaaaauca uccccuacuc cggccuccuc      840

cucgucauca ccguuaccga caacaaaggc gccuucaaau acaucaaacc ccaaucccaa      900

uucaucgucg accucggagc cuaccuugaa aaagagucca ucuacuacgu caccaccaac      960

uggaaacaca ccgccacccg auucgccauc aaacccaugg aagacuaagg acuagugucc     1020

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg     1080

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9741
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9741
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaaacauacg ugaacaagcu ucacgaaggc uccacauaca cagcugcugu ucaauacaau      120

gucuuagaaa aagacgauga cccugcauca cuuacaauau gggugcccau guuccaauca      180

ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug ucaacauacu agugaaacaa      240

auauccacac ccaagggacc uucacuaaga gucaugauaa acucaagaag ugcagugcua      300

gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu ccuuggauga aagaagcaaa      360

cuagcauaug auguaaccac acccugugaa aucaaggcau guagucuaac augccuaaaa      420

ucaaaaaaua uguugacuac aguuaaagau cucacuauga agacacucaa cccuacacau      480

gauauuauug cuuuauguga auuugaaaac auaguaacau caaaaaaagu cauaauacca      540

acauaccuaa gauccaucag ugucagaaau aaagaucuga acacacuuga aaauauaaca      600

accacugaau ucaaaaaugc uaucacaaau gcaaaaauca ucccuuacuc aggauuacua      660

uuagucauca cagugacuga caacaaagga gcauucaaau acauaaagcc acaaagucaa      720

uucauaguag aucuuggagc uuaccuagaa aaagaaagua uauauuaugu uaccacaaau      780

uggaagcaca cagcuacacg auuugcaauc aaacccaugg aagauuaagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9742
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9742
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca cggccgccgu ccaguacaac      120

gugcucgaga aggacgacga ccccgcgucc cugaccaucu gggugccgau guuccagagc      180

uccaugcccg ccgaccugcu caucaaggag cuggccaacg ucaacauccu ggugaagcag      240

aucagcaccc ccaaggggcc cucccuccgc gugaugauca acagccgguc cgccguccug      300

gcccagaugc cgagcaaguu caccaucugc gcgaacgugu cccuggacga gcgcagcaag      360

cucgccuacg acgugacgac ccccugcgag aucaaggccu gcucccugac cugccucaag      420

agcaagaaca ugcugaccac ggucaaggac cugaccauga agacccugaa ccccacccac      480

gacaucaucg cccucugcga guucgagaac aucgugacgu ccaagaaggu gaucaucccc      540

accuaccugc ggagcaucuc cguccgcaac aaggaccuga acacccucga gaacaucacc      600

acgaccgagu ucaagaacgc gaucaccaac gccaagauca ucccguacag cggccugcug      660

cucgugauca ccgugacgga caacaagggg gccuucaagu acaucaagcc ccagucccag      720

uucaucgucg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      780

uggaagcaca ccgccacgcg guucgcgauc aagcccaugg aggacugagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9743
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9743
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaccuacg ucaacaagcu ccacgagggc uccaccuaca ccgccgccgu ccaguacaac      120

guccucgaga aggacgacga ccccgccucc cucaccaucu ggguccccau guuccagucc      180

uccaugcccg ccgaccuccu caucaaggag cucgccaacg ucaacauccu cgucaagcag      240

aucuccaccc ccaagggccc cucccuccgc gucaugauca acucccgcuc cgccguccuc      300

gcccagaugc ccuccaaguu caccaucugc gccaacgucu cccucgacga gcgcuccaag      360

cucgccuacg acgucaccac ccccugcgag aucaaggccu gcucccucac cugccucaag      420

uccaagaaca ugcucaccac cgucaaggac cucaccauga agacccucaa ccccacccac      480

gacaucaucg cccucugcga guucgagaac aucgucaccu ccaagaaggu caucaucccc      540

accuaccucc gcuccaucuc cguccgcaac aaggaccuca acacccucga gaacaucacc      600

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacuc cggccuccuc      660

cucgucauca ccgucaccga caacaagggc gccuucaagu acaucaagcc ccagucccag      720

uucaucgucg accucggcgc cuaccucgag aaggagucca ucuacuacgu caccaccaac      780

uggaagcaca ccgccacccg cuucgccauc aagcccaugg aggacugagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9744
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9744
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cugccgcugu ccaguacaau      120

guucucgaga aagacgauga ccccgcaucc cuuacgaucu gggugccuau guuccaaucu      180

ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg uaaauauacu ggugaaacag      240

aucaguaccc cgaaggggcc cagccuaaga gucaugauua acuccagguc ugcugugcuc      300

gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu cacuggacga gcggagcaaa      360

cuugccuaug augugacuac cccaugugaa auuaaggcuu gcagucugac auguuugaag      420

uccaagaaca ugcucaccac ugucaaagac cugacaauga agacccugaa ucccacgcau      480

gauaucauag cacucugcga guucgagaac aucgugacuu cuaaaaaggu aauuaucccu      540

accuacuuac gcagcauuuc cguucgaaau aaggaccuga acacacuuga aaauaucacu      600

accacagagu uuaaaaacgc cauaaccaau gcuaagauua ucccauauuc aggauugcug      660

cuagugauua cggucacuga uaacaaaggu gccuucaagu acaucaaacc ccagagucaa      720

uuuaucgugg accucggcgc guaucuggaa aaggagagca uuuacuacgu gacaaccaau      780

uggaaacaca cugcaacacg uuucgccaua aagccuaugg aggauugagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9745
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9745
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca ccgccgccgu gcaguacaac      120

gugcuggaga aggacgacga ccccgccagc cugaccaucu gggugcccau guuccagagc      180

agcaugcccg ccgaccugcu gaucaaggag cuggccaacg ugaacauccu ggugaagcag      240

aucagcaccc ccaagggccc cagccugaga gugaugauca acagcagaag cgccgugcug      300

gcccagaugc ccagcaaguu caccaucugc gccaacguga gccuggacga gagaagcaag      360

cuggccuacg acgugaccac ccccugcgag aucaaggccu gcagccugac cugccugaag      420

agcaagaaca ugcugaccac cgugaaggac cugaccauga agacccugaa ccccacccac      480

gacaucaucg cccugugcga guucgagaac aucgugacca gcaagaaggu gaucaucccc      540

accuaccuga gaagcaucag cgugagaaac aaggaccuga acacccugga gaacaucacc      600

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacag cggccugcug      660

cuggugauca ccgugaccga caacaagggc gccuucaagu acaucaagcc ccagagccag      720

uucaucgugg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      780

uggaagcaca ccgccaccag auucgccauc aagcccaugg aggacugagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9746
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9746
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cggccgcugu ccaguacaau      120

guucucgaga aagacgauga ccccgccucc cugaccaucu gggugccuau guuccaaucu      180

agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg ugaauauccu ggucaaacag      240

auuuccacac ccaaggggcc uucucuuaga gugaugauca acagccgguc cgccguucug      300

gcccagaugc ccucuaaauu uaccauuugc gcuaauguga gccucgacga gcgcuccaag      360

cuggccuaug augucacaac cccuugugaa aucaaggcuu gcagccugac augucucaaa      420

ucuaagaaca ugcugaccac ggugaaagac cuuaccauga agacacugaa ucccacccau      480

gauaucauug cccucugcga guucgagaac aucguuacau ccaaaaaggu gauuaucccu      540

accuaccuga gaagcauuuc uguccggaau aaggaccuua acacgcugga aaauaucaca      600

accacagagu uuaaaaacgc gauuaccaau gccaagauca ucccguauuc cggacuccug      660

cuggugauua ccgugacaga uaacaaaggc gcuuucaagu acaucaaacc ccagagccaa      720

uuuauugucg accucggggc cuaucuggaa aaggagucua ucuacuacgu uacgaccaau      780

uggaaacaca cagcuacccg cuucgccauu aagccuaugg aggauugagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9747
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9747
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaaacauacg uaaacaaacu acacgaagga uccacauaca cagcagcagu acaauacaac      120

guacuagaaa aagacgacga cccagcaucu uuaaccauau ggguaccaau guuccaauca      180

ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg uaaacauccu agucaaacaa      240

auaucaacac ccaaaggacc aucccucaga guaaugauca acucaagauc agcaguacua      300

gcacaaaugc caucaaaauu cacaauaugc gccaacguuu cuuuagacga acgaucaaaa      360

uuagccuacg acguaacaac acccugcgaa auaaaagcau gcucacuaac augccuaaaa      420

ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga aaacacucaa cccaacacac      480

gacauaauag cccuaugcga auuugaaaac auaguaacau caaaaaaagu aauaauccca      540

acauacuuaa gaucgaucuc agucagaaac aaagaccuaa auacacucga aaacauaaca      600

acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa uaccauacuc aggacuacuc      660

cuaguaauaa caguaacaga caacaaagga gcauucaaau acauaaaacc acaaucacaa      720

uucaucguag accucggagc auaccuagaa aaagaaucaa uauacuacgu aacaacaaac      780

uggaaacaca ccgccacaag auucgcaaua aaacccaugg aagacuaagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9748
<211>  1040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9748
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca ccgccgccgu ccaauacaac      120

guccucgaaa aagacgacga ccccgccucc cuaaccaucu ggguucccau guuccaauca      180

uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg ucaacauccu agucaaacaa      240

aucagcaccc ccaaaggccc cucccuccgc guaaugauca acucccgcuc cgccguccua      300

gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu cccucgacga acgcucaaaa      360

cucgccuacg acgucaccac acccugcgaa aucaaagccu gcucccucac cugccucaaa      420

agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga aaacccucaa ccccacucac      480

gacaucauag cccucugcga auuugaaaac aucgucaccu ccaaaaaagu caucaucccc      540

acauaccucc gcuccaucuc cguccgcaac aaagaccuca acacccucga aaacaucacc      600

accaccgaau uuaaaaacgc caucaccaac gccaaaauca uccccuacuc cggccuccuc      660

cucgucauca ccguuaccga caacaaaggc gccuucaaau acaucaaacc ccaaucccaa      720

uucaucgucg accucggagc cuaccuugaa aaagagucca ucuacuacgu caccaccaac      780

uggaaacaca ccgccacccg auucgccauc aaacccaugg aagacuaagg acuagugucc      840

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      900

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1020

uuuucagagc caccagaauu                                                 1040


<210>  9749
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9749
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg ugaacaagcu ucacgaaggc uccacauaca      120

cagcugcugu ucaauacaau gucuuagaaa aagacgauga cccugcauca cuuacaauau      180

gggugcccau guuccaauca ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug      240

ucaacauacu agugaaacaa auauccacac ccaagggacc uucacuaaga gucaugauaa      300

acucaagaag ugcagugcua gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu      360

ccuuggauga aagaagcaaa cuagcauaug auguaaccac acccugugaa aucaaggcau      420

guagucuaac augccuaaaa ucaaaaaaua uguugacuac aguuaaagau cucacuauga      480

agacacucaa cccuacacau gauauuauug cuuuauguga auuugaaaac auaguaacau      540

caaaaaaagu cauaauacca acauaccuaa gauccaucag ugucagaaau aaagaucuga      600

acacacuuga aaauauaaca accacugaau ucaaaaaugc uaucacaaau gcaaaaauca      660

ucccuuacuc aggauuacua uuagucauca cagugacuga caacaaagga gcauucaaau      720

acauaaagcc acaaagucaa uucauaguag aucuuggagc uuaccuagaa aaagaaagua      780

uauauuaugu uaccacaaau uggaagcaca cagcuacacg auuugcaauc aaacccaugg      840

aagauuaagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9750
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9750
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

cggccgccgu ccaguacaac gugcucgaga aggacgacga ccccgcgucc cugaccaucu      180

gggugccgau guuccagagc uccaugcccg ccgaccugcu caucaaggag cuggccaacg      240

ucaacauccu ggugaagcag aucagcaccc ccaaggggcc cucccuccgc gugaugauca      300

acagccgguc cgccguccug gcccagaugc cgagcaaguu caccaucugc gcgaacgugu      360

cccuggacga gcgcagcaag cucgccuacg acgugacgac ccccugcgag aucaaggccu      420

gcucccugac cugccucaag agcaagaaca ugcugaccac ggucaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgugacgu      540

ccaagaaggu gaucaucccc accuaccugc ggagcaucuc cguccgcaac aaggaccuga      600

acacccucga gaacaucacc acgaccgagu ucaagaacgc gaucaccaac gccaagauca      660

ucccguacag cggccugcug cucgugauca ccgugacgga caacaagggg gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccacgcg guucgcgauc aagcccaugg      840

aggacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9751
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9751
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ucaacaagcu ccacgagggc uccaccuaca      120

ccgccgccgu ccaguacaac guccucgaga aggacgacga ccccgccucc cucaccaucu      180

ggguccccau guuccagucc uccaugcccg ccgaccuccu caucaaggag cucgccaacg      240

ucaacauccu cgucaagcag aucuccaccc ccaagggccc cucccuccgc gucaugauca      300

acucccgcuc cgccguccuc gcccagaugc ccuccaaguu caccaucugc gccaacgucu      360

cccucgacga gcgcuccaag cucgccuacg acgucaccac ccccugcgag aucaaggccu      420

gcucccucac cugccucaag uccaagaaca ugcucaccac cgucaaggac cucaccauga      480

agacccucaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgucaccu      540

ccaagaaggu caucaucccc accuaccucc gcuccaucuc cguccgcaac aaggaccuca      600

acacccucga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacuc cggccuccuc cucgucauca ccgucaccga caacaagggc gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accucggcgc cuaccucgag aaggagucca      780

ucuacuacgu caccaccaac uggaagcaca ccgccacccg cuucgccauc aagcccaugg      840

aggacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9752
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9752
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cugccgcugu ccaguacaau guucucgaga aagacgauga ccccgcaucc cuuacgaucu      180

gggugccuau guuccaaucu ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg      240

uaaauauacu ggugaaacag aucaguaccc cgaaggggcc cagccuaaga gucaugauua      300

acuccagguc ugcugugcuc gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu      360

cacuggacga gcggagcaaa cuugccuaug augugacuac cccaugugaa auuaaggcuu      420

gcagucugac auguuugaag uccaagaaca ugcucaccac ugucaaagac cugacaauga      480

agacccugaa ucccacgcau gauaucauag cacucugcga guucgagaac aucgugacuu      540

cuaaaaaggu aauuaucccu accuacuuac gcagcauuuc cguucgaaau aaggaccuga      600

acacacuuga aaauaucacu accacagagu uuaaaaacgc cauaaccaau gcuaagauua      660

ucccauauuc aggauugcug cuagugauua cggucacuga uaacaaaggu gccuucaagu      720

acaucaaacc ccagagucaa uuuaucgugg accucggcgc guaucuggaa aaggagagca      780

uuuacuacgu gacaaccaau uggaaacaca cugcaacacg uuucgccaua aagccuaugg      840

aggauugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9753
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9753
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

ccgccgccgu gcaguacaac gugcuggaga aggacgacga ccccgccagc cugaccaucu      180

gggugcccau guuccagagc agcaugcccg ccgaccugcu gaucaaggag cuggccaacg      240

ugaacauccu ggugaagcag aucagcaccc ccaagggccc cagccugaga gugaugauca      300

acagcagaag cgccgugcug gcccagaugc ccagcaaguu caccaucugc gccaacguga      360

gccuggacga gagaagcaag cuggccuacg acgugaccac ccccugcgag aucaaggccu      420

gcagccugac cugccugaag agcaagaaca ugcugaccac cgugaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccugugcga guucgagaac aucgugacca      540

gcaagaaggu gaucaucccc accuaccuga gaagcaucag cgugagaaac aaggaccuga      600

acacccugga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacag cggccugcug cuggugauca ccgugaccga caacaagggc gccuucaagu      720

acaucaagcc ccagagccag uucaucgugg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccaccag auucgccauc aagcccaugg      840

aggacugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9754
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9754
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cggccgcugu ccaguacaau guucucgaga aagacgauga ccccgccucc cugaccaucu      180

gggugccuau guuccaaucu agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg      240

ugaauauccu ggucaaacag auuuccacac ccaaggggcc uucucuuaga gugaugauca      300

acagccgguc cgccguucug gcccagaugc ccucuaaauu uaccauuugc gcuaauguga      360

gccucgacga gcgcuccaag cuggccuaug augucacaac cccuugugaa aucaaggcuu      420

gcagccugac augucucaaa ucuaagaaca ugcugaccac ggugaaagac cuuaccauga      480

agacacugaa ucccacccau gauaucauug cccucugcga guucgagaac aucguuacau      540

ccaaaaaggu gauuaucccu accuaccuga gaagcauuuc uguccggaau aaggaccuua      600

acacgcugga aaauaucaca accacagagu uuaaaaacgc gauuaccaau gccaagauca      660

ucccguauuc cggacuccug cuggugauua ccgugacaga uaacaaaggc gcuuucaagu      720

acaucaaacc ccagagccaa uuuauugucg accucggggc cuaucuggaa aaggagucua      780

ucuacuacgu uacgaccaau uggaaacaca cagcuacccg cuucgccauu aagccuaugg      840

aggauugagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9755
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9755
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg uaaacaaacu acacgaagga uccacauaca      120

cagcagcagu acaauacaac guacuagaaa aagacgacga cccagcaucu uuaaccauau      180

ggguaccaau guuccaauca ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg      240

uaaacauccu agucaaacaa auaucaacac ccaaaggacc aucccucaga guaaugauca      300

acucaagauc agcaguacua gcacaaaugc caucaaaauu cacaauaugc gccaacguuu      360

cuuuagacga acgaucaaaa uuagccuacg acguaacaac acccugcgaa auaaaagcau      420

gcucacuaac augccuaaaa ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga      480

aaacacucaa cccaacacac gacauaauag cccuaugcga auuugaaaac auaguaacau      540

caaaaaaagu aauaauccca acauacuuaa gaucgaucuc agucagaaac aaagaccuaa      600

auacacucga aaacauaaca acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa      660

uaccauacuc aggacuacuc cuaguaauaa caguaacaga caacaaagga gcauucaaau      720

acauaaaacc acaaucacaa uucaucguag accucggagc auaccuagaa aaagaaucaa      780

uauacuacgu aacaacaaac uggaaacaca ccgccacaag auucgcaaua aaacccaugg      840

aagacuaagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9756
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9756
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca      120

ccgccgccgu ccaauacaac guccucgaaa aagacgacga ccccgccucc cuaaccaucu      180

ggguucccau guuccaauca uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg      240

ucaacauccu agucaaacaa aucagcaccc ccaaaggccc cucccuccgc guaaugauca      300

acucccgcuc cgccguccua gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu      360

cccucgacga acgcucaaaa cucgccuacg acgucaccac acccugcgaa aucaaagccu      420

gcucccucac cugccucaaa agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga      480

aaacccucaa ccccacucac gacaucauag cccucugcga auuugaaaac aucgucaccu      540

ccaaaaaagu caucaucccc acauaccucc gcuccaucuc cguccgcaac aaagaccuca      600

acacccucga aaacaucacc accaccgaau uuaaaaacgc caucaccaac gccaaaauca      660

uccccuacuc cggccuccuc cucgucauca ccguuaccga caacaaaggc gccuucaaau      720

acaucaaacc ccaaucccaa uucaucgucg accucggagc cuaccuugaa aaagagucca      780

ucuacuacgu caccaccaac uggaaacaca ccgccacccg auucgccauc aaacccaugg      840

aagacuaagg acuagugucc accugucccu ccugggcugc uggauugucu cguuuuccug      900

ccaaauaaac aggaucagcg cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9757
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9757
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg ugaacaagcu ucacgaaggc uccacauaca      120

cagcugcugu ucaauacaau gucuuagaaa aagacgauga cccugcauca cuuacaauau      180

gggugcccau guuccaauca ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug      240

ucaacauacu agugaaacaa auauccacac ccaagggacc uucacuaaga gucaugauaa      300

acucaagaag ugcagugcua gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu      360

ccuuggauga aagaagcaaa cuagcauaug auguaaccac acccugugaa aucaaggcau      420

guagucuaac augccuaaaa ucaaaaaaua uguugacuac aguuaaagau cucacuauga      480

agacacucaa cccuacacau gauauuauug cuuuauguga auuugaaaac auaguaacau      540

caaaaaaagu cauaauacca acauaccuaa gauccaucag ugucagaaau aaagaucuga      600

acacacuuga aaauauaaca accacugaau ucaaaaaugc uaucacaaau gcaaaaauca      660

ucccuuacuc aggauuacua uuagucauca cagugacuga caacaaagga gcauucaaau      720

acauaaagcc acaaagucaa uucauaguag aucuuggagc uuaccuagaa aaagaaagua      780

uauauuaugu uaccacaaau uggaagcaca cagcuacacg auuugcaauc aaacccaugg      840

aagauuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9758
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9758
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

cggccgccgu ccaguacaac gugcucgaga aggacgacga ccccgcgucc cugaccaucu      180

gggugccgau guuccagagc uccaugcccg ccgaccugcu caucaaggag cuggccaacg      240

ucaacauccu ggugaagcag aucagcaccc ccaaggggcc cucccuccgc gugaugauca      300

acagccgguc cgccguccug gcccagaugc cgagcaaguu caccaucugc gcgaacgugu      360

cccuggacga gcgcagcaag cucgccuacg acgugacgac ccccugcgag aucaaggccu      420

gcucccugac cugccucaag agcaagaaca ugcugaccac ggucaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgugacgu      540

ccaagaaggu gaucaucccc accuaccugc ggagcaucuc cguccgcaac aaggaccuga      600

acacccucga gaacaucacc acgaccgagu ucaagaacgc gaucaccaac gccaagauca      660

ucccguacag cggccugcug cucgugauca ccgugacgga caacaagggg gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccacgcg guucgcgauc aagcccaugg      840

aggacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9759
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9759
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ucaacaagcu ccacgagggc uccaccuaca      120

ccgccgccgu ccaguacaac guccucgaga aggacgacga ccccgccucc cucaccaucu      180

ggguccccau guuccagucc uccaugcccg ccgaccuccu caucaaggag cucgccaacg      240

ucaacauccu cgucaagcag aucuccaccc ccaagggccc cucccuccgc gucaugauca      300

acucccgcuc cgccguccuc gcccagaugc ccuccaaguu caccaucugc gccaacgucu      360

cccucgacga gcgcuccaag cucgccuacg acgucaccac ccccugcgag aucaaggccu      420

gcucccucac cugccucaag uccaagaaca ugcucaccac cgucaaggac cucaccauga      480

agacccucaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgucaccu      540

ccaagaaggu caucaucccc accuaccucc gcuccaucuc cguccgcaac aaggaccuca      600

acacccucga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacuc cggccuccuc cucgucauca ccgucaccga caacaagggc gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accucggcgc cuaccucgag aaggagucca      780

ucuacuacgu caccaccaac uggaagcaca ccgccacccg cuucgccauc aagcccaugg      840

aggacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9760
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9760
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cugccgcugu ccaguacaau guucucgaga aagacgauga ccccgcaucc cuuacgaucu      180

gggugccuau guuccaaucu ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg      240

uaaauauacu ggugaaacag aucaguaccc cgaaggggcc cagccuaaga gucaugauua      300

acuccagguc ugcugugcuc gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu      360

cacuggacga gcggagcaaa cuugccuaug augugacuac cccaugugaa auuaaggcuu      420

gcagucugac auguuugaag uccaagaaca ugcucaccac ugucaaagac cugacaauga      480

agacccugaa ucccacgcau gauaucauag cacucugcga guucgagaac aucgugacuu      540

cuaaaaaggu aauuaucccu accuacuuac gcagcauuuc cguucgaaau aaggaccuga      600

acacacuuga aaauaucacu accacagagu uuaaaaacgc cauaaccaau gcuaagauua      660

ucccauauuc aggauugcug cuagugauua cggucacuga uaacaaaggu gccuucaagu      720

acaucaaacc ccagagucaa uuuaucgugg accucggcgc guaucuggaa aaggagagca      780

uuuacuacgu gacaaccaau uggaaacaca cugcaacacg uuucgccaua aagccuaugg      840

aggauugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9761
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9761
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

ccgccgccgu gcaguacaac gugcuggaga aggacgacga ccccgccagc cugaccaucu      180

gggugcccau guuccagagc agcaugcccg ccgaccugcu gaucaaggag cuggccaacg      240

ugaacauccu ggugaagcag aucagcaccc ccaagggccc cagccugaga gugaugauca      300

acagcagaag cgccgugcug gcccagaugc ccagcaaguu caccaucugc gccaacguga      360

gccuggacga gagaagcaag cuggccuacg acgugaccac ccccugcgag aucaaggccu      420

gcagccugac cugccugaag agcaagaaca ugcugaccac cgugaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccugugcga guucgagaac aucgugacca      540

gcaagaaggu gaucaucccc accuaccuga gaagcaucag cgugagaaac aaggaccuga      600

acacccugga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacag cggccugcug cuggugauca ccgugaccga caacaagggc gccuucaagu      720

acaucaagcc ccagagccag uucaucgugg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccaccag auucgccauc aagcccaugg      840

aggacugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9762
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9762
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cggccgcugu ccaguacaau guucucgaga aagacgauga ccccgccucc cugaccaucu      180

gggugccuau guuccaaucu agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg      240

ugaauauccu ggucaaacag auuuccacac ccaaggggcc uucucuuaga gugaugauca      300

acagccgguc cgccguucug gcccagaugc ccucuaaauu uaccauuugc gcuaauguga      360

gccucgacga gcgcuccaag cuggccuaug augucacaac cccuugugaa aucaaggcuu      420

gcagccugac augucucaaa ucuaagaaca ugcugaccac ggugaaagac cuuaccauga      480

agacacugaa ucccacccau gauaucauug cccucugcga guucgagaac aucguuacau      540

ccaaaaaggu gauuaucccu accuaccuga gaagcauuuc uguccggaau aaggaccuua      600

acacgcugga aaauaucaca accacagagu uuaaaaacgc gauuaccaau gccaagauca      660

ucccguauuc cggacuccug cuggugauua ccgugacaga uaacaaaggc gcuuucaagu      720

acaucaaacc ccagagccaa uuuauugucg accucggggc cuaucuggaa aaggagucua      780

ucuacuacgu uacgaccaau uggaaacaca cagcuacccg cuucgccauu aagccuaugg      840

aggauugagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9763
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9763
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg uaaacaaacu acacgaagga uccacauaca      120

cagcagcagu acaauacaac guacuagaaa aagacgacga cccagcaucu uuaaccauau      180

ggguaccaau guuccaauca ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg      240

uaaacauccu agucaaacaa auaucaacac ccaaaggacc aucccucaga guaaugauca      300

acucaagauc agcaguacua gcacaaaugc caucaaaauu cacaauaugc gccaacguuu      360

cuuuagacga acgaucaaaa uuagccuacg acguaacaac acccugcgaa auaaaagcau      420

gcucacuaac augccuaaaa ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga      480

aaacacucaa cccaacacac gacauaauag cccuaugcga auuugaaaac auaguaacau      540

caaaaaaagu aauaauccca acauacuuaa gaucgaucuc agucagaaac aaagaccuaa      600

auacacucga aaacauaaca acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa      660

uaccauacuc aggacuacuc cuaguaauaa caguaacaga caacaaagga gcauucaaau      720

acauaaaacc acaaucacaa uucaucguag accucggagc auaccuagaa aaagaaucaa      780

uauacuacgu aacaacaaac uggaaacaca ccgccacaag auucgcaaua aaacccaugg      840

aagacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9764
<211>  1111
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9764
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca      120

ccgccgccgu ccaauacaac guccucgaaa aagacgacga ccccgccucc cuaaccaucu      180

ggguucccau guuccaauca uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg      240

ucaacauccu agucaaacaa aucagcaccc ccaaaggccc cucccuccgc guaaugauca      300

acucccgcuc cgccguccua gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu      360

cccucgacga acgcucaaaa cucgccuacg acgucaccac acccugcgaa aucaaagccu      420

gcucccucac cugccucaaa agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga      480

aaacccucaa ccccacucac gacaucauag cccucugcga auuugaaaac aucgucaccu      540

ccaaaaaagu caucaucccc acauaccucc gcuccaucuc cguccgcaac aaagaccuca      600

acacccucga aaacaucacc accaccgaau uuaaaaacgc caucaccaac gccaaaauca      660

uccccuacuc cggccuccuc cucgucauca ccguuaccga caacaaaggc gccuucaaau      720

acaucaaacc ccaaucccaa uucaucgucg accucggagc cuaccuugaa aaagagucca      780

ucuacuacgu caccaccaac uggaaacaca ccgccacccg auucgccauc aaacccaugg      840

aagacuaagg acuaguaaua aggaaacugu augaaugucu gugggcagga agugaagaga      900

uccuucugua aagguuuuug gaauuauguc ugcugaauaa uaaacuuuuu ugaaauaaua      960

aaucugguag aaaaaugaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1080

cccaaaggcu cuuuucagag ccaccagaau u                                    1111


<210>  9765
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9765
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacgugaa caagcuucac gaaggcucca cauacacagc ugcuguucaa      180

uacaaugucu uagaaaaaga cgaugacccu gcaucacuua caauaugggu gcccauguuc      240

caaucaucua ugccagcaga uuuacuuaua aaagaacuag cuaaugucaa cauacuagug      300

aaacaaauau ccacacccaa gggaccuuca cuaagaguca ugauaaacuc aagaagugca      360

gugcuagcac aaaugcccag caaauuuacc auaugcgcua auguguccuu ggaugaaaga      420

agcaaacuag cauaugaugu aaccacaccc ugugaaauca aggcauguag ucuaacaugc      480

cuaaaaucaa aaaauauguu gacuacaguu aaagaucuca cuaugaagac acucaacccu      540

acacaugaua uuauugcuuu augugaauuu gaaaacauag uaacaucaaa aaaagucaua      600

auaccaacau accuaagauc caucaguguc agaaauaaag aucugaacac acuugaaaau      660

auaacaacca cugaauucaa aaaugcuauc acaaaugcaa aaaucauccc uuacucagga      720

uuacuauuag ucaucacagu gacugacaac aaaggagcau ucaaauacau aaagccacaa      780

agucaauuca uaguagaucu uggagcuuac cuagaaaaag aaaguauaua uuauguuacc      840

acaaauugga agcacacagc uacacgauuu gcaaucaaac ccauggaaga uuaaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9766
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9766
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacacggc cgccguccag      180

uacaacgugc ucgagaagga cgacgacccc gcgucccuga ccaucugggu gccgauguuc      240

cagagcucca ugcccgccga ccugcucauc aaggagcugg ccaacgucaa cauccuggug      300

aagcagauca gcacccccaa ggggcccucc cuccgcguga ugaucaacag ccgguccgcc      360

guccuggccc agaugccgag caaguucacc aucugcgcga acgugucccu ggacgagcgc      420

agcaagcucg ccuacgacgu gacgaccccc ugcgagauca aggccugcuc ccugaccugc      480

cucaagagca agaacaugcu gaccacgguc aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ugacguccaa gaaggugauc      600

auccccaccu accugcggag caucuccguc cgcaacaagg accugaacac ccucgagaac      660

aucaccacga ccgaguucaa gaacgcgauc accaacgcca agaucauccc guacagcggc      720

cugcugcucg ugaucaccgu gacggacaac aagggggccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc cacgcgguuc gcgaucaagc ccauggagga cugaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9767
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9767
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgucaa caagcuccac gagggcucca ccuacaccgc cgccguccag      180

uacaacgucc ucgagaagga cgacgacccc gccucccuca ccaucugggu ccccauguuc      240

caguccucca ugcccgccga ccuccucauc aaggagcucg ccaacgucaa cauccucguc      300

aagcagaucu ccacccccaa gggccccucc cuccgcguca ugaucaacuc ccgcuccgcc      360

guccucgccc agaugcccuc caaguucacc aucugcgcca acgucucccu cgacgagcgc      420

uccaagcucg ccuacgacgu caccaccccc ugcgagauca aggccugcuc ccucaccugc      480

cucaagucca agaacaugcu caccaccguc aaggaccuca ccaugaagac ccucaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ucaccuccaa gaaggucauc      600

auccccaccu accuccgcuc caucuccguc cgcaacaagg accucaacac ccucgagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu caccgacaac aagggcgccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu cggcgccuac cucgagaagg aguccaucua cuacgucacc      840

accaacugga agcacaccgc cacccgcuuc gccaucaagc ccauggagga cugaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9768
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9768
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacugc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gcaucccuua cgaucugggu gccuauguuc      240

caaucuucaa ugccagccga ucuguugauu aaggaauuag cgaacguaaa uauacuggug      300

aaacagauca guaccccgaa ggggcccagc cuaagaguca ugauuaacuc caggucugcu      360

gugcucgccc agaugccuuc gaaauuuaca aucugcgcaa auguuucacu ggacgagcgg      420

agcaaacuug ccuaugaugu gacuacccca ugugaaauua aggcuugcag ucugacaugu      480

uugaagucca agaacaugcu caccacuguc aaagaccuga caaugaagac ccugaauccc      540

acgcaugaua ucauagcacu cugcgaguuc gagaacaucg ugacuucuaa aaagguaauu      600

aucccuaccu acuuacgcag cauuuccguu cgaaauaagg accugaacac acuugaaaau      660

aucacuacca cagaguuuaa aaacgccaua accaaugcua agauuauccc auauucagga      720

uugcugcuag ugauuacggu cacugauaac aaaggugccu ucaaguacau caaaccccag      780

agucaauuua ucguggaccu cggcgcguau cuggaaaagg agagcauuua cuacgugaca      840

accaauugga aacacacugc aacacguuuc gccauaaagc cuauggagga uugaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9769
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9769
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacaccgc cgccgugcag      180

uacaacgugc uggagaagga cgacgacccc gccagccuga ccaucugggu gcccauguuc      240

cagagcagca ugcccgccga ccugcugauc aaggagcugg ccaacgugaa cauccuggug      300

aagcagauca gcacccccaa gggccccagc cugagaguga ugaucaacag cagaagcgcc      360

gugcuggccc agaugcccag caaguucacc aucugcgcca acgugagccu ggacgagaga      420

agcaagcugg ccuacgacgu gaccaccccc ugcgagauca aggccugcag ccugaccugc      480

cugaagagca agaacaugcu gaccaccgug aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu gugcgaguuc gagaacaucg ugaccagcaa gaaggugauc      600

auccccaccu accugagaag caucagcgug agaaacaagg accugaacac ccuggagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacagcggc      720

cugcugcugg ugaucaccgu gaccgacaac aagggcgccu ucaaguacau caagccccag      780

agccaguuca ucguggaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc caccagauuc gccaucaagc ccauggagga cugaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9770
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9770
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacggc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gccucccuga ccaucugggu gccuauguuc      240

caaucuagca ugccggcgga ucuucugauu aaggaacucg cuaacgugaa uauccugguc      300

aaacagauuu ccacacccaa ggggccuucu cuuagaguga ugaucaacag ccgguccgcc      360

guucuggccc agaugcccuc uaaauuuacc auuugcgcua augugagccu cgacgagcgc      420

uccaagcugg ccuaugaugu cacaaccccu ugugaaauca aggcuugcag ccugacaugu      480

cucaaaucua agaacaugcu gaccacggug aaagaccuua ccaugaagac acugaauccc      540

acccaugaua ucauugcccu cugcgaguuc gagaacaucg uuacauccaa aaaggugauu      600

aucccuaccu accugagaag cauuucuguc cggaauaagg accuuaacac gcuggaaaau      660

aucacaacca cagaguuuaa aaacgcgauu accaaugcca agaucauccc guauuccgga      720

cuccugcugg ugauuaccgu gacagauaac aaaggcgcuu ucaaguacau caaaccccag      780

agccaauuua uugucgaccu cggggccuau cuggaaaagg agucuaucua cuacguuacg      840

accaauugga aacacacagc uacccgcuuc gccauuaagc cuauggagga uugaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9771
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9771
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacguaaa caaacuacac gaaggaucca cauacacagc agcaguacaa      180

uacaacguac uagaaaaaga cgacgaccca gcaucuuuaa ccauaugggu accaauguuc      240

caaucaucaa ugccagcaga ccucuuaaua aaagaacuag caaacguaaa cauccuaguc      300

aaacaaauau caacacccaa aggaccaucc cucagaguaa ugaucaacuc aagaucagca      360

guacuagcac aaaugccauc aaaauucaca auaugcgcca acguuucuuu agacgaacga      420

ucaaaauuag ccuacgacgu aacaacaccc ugcgaaauaa aagcaugcuc acuaacaugc      480

cuaaaaucaa aaaacaugcu cacuacagua aaagaccuaa ccaugaaaac acucaaccca      540

acacacgaca uaauagcccu augcgaauuu gaaaacauag uaacaucaaa aaaaguaaua      600

aucccaacau acuuaagauc gaucucaguc agaaacaaag accuaaauac acucgaaaac      660

auaacaacaa cagaauuuaa aaacgcaaua acaaacgcaa aaauaauacc auacucagga      720

cuacuccuag uaauaacagu aacagacaac aaaggagcau ucaaauacau aaaaccacaa      780

ucacaauuca ucguagaccu cggagcauac cuagaaaaag aaucaauaua cuacguaaca      840

acaaacugga aacacaccgc cacaagauuc gcaauaaaac ccauggaaga cuaaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9772
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9772
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa ccuacgucaa caaacuacac gaaggcucaa ccuacaccgc cgccguccaa      180

uacaacgucc ucgaaaaaga cgacgacccc gccucccuaa ccaucugggu ucccauguuc      240

caaucaucca ugcccgccga ccuccucaua aaagaacuag ccaacgucaa cauccuaguc      300

aaacaaauca gcacccccaa aggccccucc cuccgcguaa ugaucaacuc ccgcuccgcc      360

guccuagccc aaaugcccuc caaauuuaca aucugcgcca acgucucccu cgacgaacgc      420

ucaaaacucg ccuacgacgu caccacaccc ugcgaaauca aagccugcuc ccucaccugc      480

cucaaaagca aaaauaugcu aaccaccguc aaagaccuua ccaugaaaac ccucaacccc      540

acucacgaca ucauagcccu cugcgaauuu gaaaacaucg ucaccuccaa aaaagucauc      600

auccccacau accuccgcuc caucuccguc cgcaacaaag accucaacac ccucgaaaac      660

aucaccacca ccgaauuuaa aaacgccauc accaacgcca aaaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu uaccgacaac aaaggcgccu ucaaauacau caaaccccaa      780

ucccaauuca ucgucgaccu cggagccuac cuugaaaaag aguccaucua cuacgucacc      840

accaacugga aacacaccgc cacccgauuc gccaucaaac ccauggaaga cuaaggacua      900

guacuggcug caucucccuu uccucugucc uccauccuuc ucccaggaug gugaaggggg      960

accugguacc cagugauccc caccccagga uccuaaauca ugacuuaccu gcuaauaaaa     1020

acucauugga aaagugagaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     1140

cccccaaagg cucuuuucag agccaccaga auu                                  1173


<210>  9773
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9773
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu gaacaagcuu      120

cacgaaggcu ccacauacac agcugcuguu caauacaaug ucuuagaaaa agacgaugac      180

ccugcaucac uuacaauaug ggugcccaug uuccaaucau cuaugccagc agauuuacuu      240

auaaaagaac uagcuaaugu caacauacua gugaaacaaa uauccacacc caagggaccu      300

ucacuaagag ucaugauaaa cucaagaagu gcagugcuag cacaaaugcc cagcaaauuu      360

accauaugcg cuaauguguc cuuggaugaa agaagcaaac uagcauauga uguaaccaca      420

cccugugaaa ucaaggcaug uagucuaaca ugccuaaaau caaaaaauau guugacuaca      480

guuaaagauc ucacuaugaa gacacucaac ccuacacaug auauuauugc uuuaugugaa      540

uuugaaaaca uaguaacauc aaaaaaaguc auaauaccaa cauaccuaag auccaucagu      600

gucagaaaua aagaucugaa cacacuugaa aauauaacaa ccacugaauu caaaaaugcu      660

aucacaaaug caaaaaucau cccuuacuca ggauuacuau uagucaucac agugacugac      720

aacaaaggag cauucaaaua cauaaagcca caaagucaau ucauaguaga ucuuggagcu      780

uaccuagaaa aagaaaguau auauuauguu accacaaauu ggaagcacac agcuacacga      840

uuugcaauca aacccaugga agauuaagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9774
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9774
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac ggccgccguc caguacaacg ugcucgagaa ggacgacgac      180

cccgcguccc ugaccaucug ggugccgaug uuccagagcu ccaugcccgc cgaccugcuc      240

aucaaggagc uggccaacgu caacauccug gugaagcaga ucagcacccc caaggggccc      300

ucccuccgcg ugaugaucaa cagccggucc gccguccugg cccagaugcc gagcaaguuc      360

accaucugcg cgaacguguc ccuggacgag cgcagcaagc ucgccuacga cgugacgacc      420

cccugcgaga ucaaggccug cucccugacc ugccucaaga gcaagaacau gcugaccacg      480

gucaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgugacguc caagaaggug aucaucccca ccuaccugcg gagcaucucc      600

guccgcaaca aggaccugaa cacccucgag aacaucacca cgaccgaguu caagaacgcg      660

aucaccaacg ccaagaucau cccguacagc ggccugcugc ucgugaucac cgugacggac      720

aacaaggggg ccuucaagua caucaagccc cagucccagu ucaucgucga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccacgcgg      840

uucgcgauca agcccaugga ggacugagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9775
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9775
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu caacaagcuc      120

cacgagggcu ccaccuacac cgccgccguc caguacaacg uccucgagaa ggacgacgac      180

cccgccuccc ucaccaucug gguccccaug uuccaguccu ccaugcccgc cgaccuccuc      240

aucaaggagc ucgccaacgu caacauccuc gucaagcaga ucuccacccc caagggcccc      300

ucccuccgcg ucaugaucaa cucccgcucc gccguccucg cccagaugcc cuccaaguuc      360

accaucugcg ccaacgucuc ccucgacgag cgcuccaagc ucgccuacga cgucaccacc      420

cccugcgaga ucaaggccug cucccucacc ugccucaagu ccaagaacau gcucaccacc      480

gucaaggacc ucaccaugaa gacccucaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgucaccuc caagaagguc aucaucccca ccuaccuccg cuccaucucc      600

guccgcaaca aggaccucaa cacccucgag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacucc ggccuccucc ucgucaucac cgucaccgac      720

aacaagggcg ccuucaagua caucaagccc cagucccagu ucaucgucga ccucggcgcc      780

uaccucgaga aggaguccau cuacuacguc accaccaacu ggaagcacac cgccacccgc      840

uucgccauca agcccaugga ggacugagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9776
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9776
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ugccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgcauccc uuacgaucug ggugccuaug uuccaaucuu caaugccagc cgaucuguug      240

auuaaggaau uagcgaacgu aaauauacug gugaaacaga ucaguacccc gaaggggccc      300

agccuaagag ucaugauuaa cuccaggucu gcugugcucg cccagaugcc uucgaaauuu      360

acaaucugcg caaauguuuc acuggacgag cggagcaaac uugccuauga ugugacuacc      420

ccaugugaaa uuaaggcuug cagucugaca uguuugaagu ccaagaacau gcucaccacu      480

gucaaagacc ugacaaugaa gacccugaau cccacgcaug auaucauagc acucugcgag      540

uucgagaaca ucgugacuuc uaaaaaggua auuaucccua ccuacuuacg cagcauuucc      600

guucgaaaua aggaccugaa cacacuugaa aauaucacua ccacagaguu uaaaaacgcc      660

auaaccaaug cuaagauuau cccauauuca ggauugcugc uagugauuac ggucacugau      720

aacaaaggug ccuucaagua caucaaaccc cagagucaau uuaucgugga ccucggcgcg      780

uaucuggaaa aggagagcau uuacuacgug acaaccaauu ggaaacacac ugcaacacgu      840

uucgccauaa agccuaugga ggauugagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9777
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9777
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac cgccgccgug caguacaacg ugcuggagaa ggacgacgac      180

cccgccagcc ugaccaucug ggugcccaug uuccagagca gcaugcccgc cgaccugcug      240

aucaaggagc uggccaacgu gaacauccug gugaagcaga ucagcacccc caagggcccc      300

agccugagag ugaugaucaa cagcagaagc gccgugcugg cccagaugcc cagcaaguuc      360

accaucugcg ccaacgugag ccuggacgag agaagcaagc uggccuacga cgugaccacc      420

cccugcgaga ucaaggccug cagccugacc ugccugaaga gcaagaacau gcugaccacc      480

gugaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccugugcgag      540

uucgagaaca ucgugaccag caagaaggug aucaucccca ccuaccugag aagcaucagc      600

gugagaaaca aggaccugaa cacccuggag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacagc ggccugcugc uggugaucac cgugaccgac      720

aacaagggcg ccuucaagua caucaagccc cagagccagu ucaucgugga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccaccaga      840

uucgccauca agcccaugga ggacugagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9778
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9778
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ggccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgccuccc ugaccaucug ggugccuaug uuccaaucua gcaugccggc ggaucuucug      240

auuaaggaac ucgcuaacgu gaauauccug gucaaacaga uuuccacacc caaggggccu      300

ucucuuagag ugaugaucaa cagccggucc gccguucugg cccagaugcc cucuaaauuu      360

accauuugcg cuaaugugag ccucgacgag cgcuccaagc uggccuauga ugucacaacc      420

ccuugugaaa ucaaggcuug cagccugaca ugucucaaau cuaagaacau gcugaccacg      480

gugaaagacc uuaccaugaa gacacugaau cccacccaug auaucauugc ccucugcgag      540

uucgagaaca ucguuacauc caaaaaggug auuaucccua ccuaccugag aagcauuucu      600

guccggaaua aggaccuuaa cacgcuggaa aauaucacaa ccacagaguu uaaaaacgcg      660

auuaccaaug ccaagaucau cccguauucc ggacuccugc uggugauuac cgugacagau      720

aacaaaggcg cuuucaagua caucaaaccc cagagccaau uuauugucga ccucggggcc      780

uaucuggaaa aggagucuau cuacuacguu acgaccaauu ggaaacacac agcuacccgc      840

uucgccauua agccuaugga ggauugagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9779
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9779
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu aaacaaacua      120

cacgaaggau ccacauacac agcagcagua caauacaacg uacuagaaaa agacgacgac      180

ccagcaucuu uaaccauaug gguaccaaug uuccaaucau caaugccagc agaccucuua      240

auaaaagaac uagcaaacgu aaacauccua gucaaacaaa uaucaacacc caaaggacca      300

ucccucagag uaaugaucaa cucaagauca gcaguacuag cacaaaugcc aucaaaauuc      360

acaauaugcg ccaacguuuc uuuagacgaa cgaucaaaau uagccuacga cguaacaaca      420

cccugcgaaa uaaaagcaug cucacuaaca ugccuaaaau caaaaaacau gcucacuaca      480

guaaaagacc uaaccaugaa aacacucaac ccaacacacg acauaauagc ccuaugcgaa      540

uuugaaaaca uaguaacauc aaaaaaagua auaaucccaa cauacuuaag aucgaucuca      600

gucagaaaca aagaccuaaa uacacucgaa aacauaacaa caacagaauu uaaaaacgca      660

auaacaaacg caaaaauaau accauacuca ggacuacucc uaguaauaac aguaacagac      720

aacaaaggag cauucaaaua cauaaaacca caaucacaau ucaucguaga ccucggagca      780

uaccuagaaa aagaaucaau auacuacgua acaacaaacu ggaaacacac cgccacaaga      840

uucgcaauaa aacccaugga agacuaagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9780
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9780
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaccuacgu caacaaacua      120

cacgaaggcu caaccuacac cgccgccguc caauacaacg uccucgaaaa agacgacgac      180

cccgccuccc uaaccaucug gguucccaug uuccaaucau ccaugcccgc cgaccuccuc      240

auaaaagaac uagccaacgu caacauccua gucaaacaaa ucagcacccc caaaggcccc      300

ucccuccgcg uaaugaucaa cucccgcucc gccguccuag cccaaaugcc cuccaaauuu      360

acaaucugcg ccaacgucuc ccucgacgaa cgcucaaaac ucgccuacga cgucaccaca      420

cccugcgaaa ucaaagccug cucccucacc ugccucaaaa gcaaaaauau gcuaaccacc      480

gucaaagacc uuaccaugaa aacccucaac cccacucacg acaucauagc ccucugcgaa      540

uuugaaaaca ucgucaccuc caaaaaaguc aucaucccca cauaccuccg cuccaucucc      600

guccgcaaca aagaccucaa cacccucgaa aacaucacca ccaccgaauu uaaaaacgcc      660

aucaccaacg ccaaaaucau ccccuacucc ggccuccucc ucgucaucac cguuaccgac      720

aacaaaggcg ccuucaaaua caucaaaccc caaucccaau ucaucgucga ccucggagcc      780

uaccuugaaa aagaguccau cuacuacguc accaccaacu ggaaacacac cgccacccga      840

uucgccauca aacccaugga agacuaagga cuagugucca ccugucccuc cugggcugcu      900

ggauugucuc guuuuccugc caaauaaaca ggaucagcgc uuuacagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  9781
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9781
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacgugaa caagcuucac gaaggcucca cauacacagc ugcuguucaa      180

uacaaugucu uagaaaaaga cgaugacccu gcaucacuua caauaugggu gcccauguuc      240

caaucaucua ugccagcaga uuuacuuaua aaagaacuag cuaaugucaa cauacuagug      300

aaacaaauau ccacacccaa gggaccuuca cuaagaguca ugauaaacuc aagaagugca      360

gugcuagcac aaaugcccag caaauuuacc auaugcgcua auguguccuu ggaugaaaga      420

agcaaacuag cauaugaugu aaccacaccc ugugaaauca aggcauguag ucuaacaugc      480

cuaaaaucaa aaaauauguu gacuacaguu aaagaucuca cuaugaagac acucaacccu      540

acacaugaua uuauugcuuu augugaauuu gaaaacauag uaacaucaaa aaaagucaua      600

auaccaacau accuaagauc caucaguguc agaaauaaag aucugaacac acuugaaaau      660

auaacaacca cugaauucaa aaaugcuauc acaaaugcaa aaaucauccc uuacucagga      720

uuacuauuag ucaucacagu gacugacaac aaaggagcau ucaaauacau aaagccacaa      780

agucaauuca uaguagaucu uggagcuuac cuagaaaaag aaaguauaua uuauguuacc      840

acaaauugga agcacacagc uacacgauuu gcaaucaaac ccauggaaga uuaaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9782
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9782
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacacggc cgccguccag      180

uacaacgugc ucgagaagga cgacgacccc gcgucccuga ccaucugggu gccgauguuc      240

cagagcucca ugcccgccga ccugcucauc aaggagcugg ccaacgucaa cauccuggug      300

aagcagauca gcacccccaa ggggcccucc cuccgcguga ugaucaacag ccgguccgcc      360

guccuggccc agaugccgag caaguucacc aucugcgcga acgugucccu ggacgagcgc      420

agcaagcucg ccuacgacgu gacgaccccc ugcgagauca aggccugcuc ccugaccugc      480

cucaagagca agaacaugcu gaccacgguc aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ugacguccaa gaaggugauc      600

auccccaccu accugcggag caucuccguc cgcaacaagg accugaacac ccucgagaac      660

aucaccacga ccgaguucaa gaacgcgauc accaacgcca agaucauccc guacagcggc      720

cugcugcucg ugaucaccgu gacggacaac aagggggccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc cacgcgguuc gcgaucaagc ccauggagga cugaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9783
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9783
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgucaa caagcuccac gagggcucca ccuacaccgc cgccguccag      180

uacaacgucc ucgagaagga cgacgacccc gccucccuca ccaucugggu ccccauguuc      240

caguccucca ugcccgccga ccuccucauc aaggagcucg ccaacgucaa cauccucguc      300

aagcagaucu ccacccccaa gggccccucc cuccgcguca ugaucaacuc ccgcuccgcc      360

guccucgccc agaugcccuc caaguucacc aucugcgcca acgucucccu cgacgagcgc      420

uccaagcucg ccuacgacgu caccaccccc ugcgagauca aggccugcuc ccucaccugc      480

cucaagucca agaacaugcu caccaccguc aaggaccuca ccaugaagac ccucaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ucaccuccaa gaaggucauc      600

auccccaccu accuccgcuc caucuccguc cgcaacaagg accucaacac ccucgagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu caccgacaac aagggcgccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu cggcgccuac cucgagaagg aguccaucua cuacgucacc      840

accaacugga agcacaccgc cacccgcuuc gccaucaagc ccauggagga cugaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9784
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9784
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacugc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gcaucccuua cgaucugggu gccuauguuc      240

caaucuucaa ugccagccga ucuguugauu aaggaauuag cgaacguaaa uauacuggug      300

aaacagauca guaccccgaa ggggcccagc cuaagaguca ugauuaacuc caggucugcu      360

gugcucgccc agaugccuuc gaaauuuaca aucugcgcaa auguuucacu ggacgagcgg      420

agcaaacuug ccuaugaugu gacuacccca ugugaaauua aggcuugcag ucugacaugu      480

uugaagucca agaacaugcu caccacuguc aaagaccuga caaugaagac ccugaauccc      540

acgcaugaua ucauagcacu cugcgaguuc gagaacaucg ugacuucuaa aaagguaauu      600

aucccuaccu acuuacgcag cauuuccguu cgaaauaagg accugaacac acuugaaaau      660

aucacuacca cagaguuuaa aaacgccaua accaaugcua agauuauccc auauucagga      720

uugcugcuag ugauuacggu cacugauaac aaaggugccu ucaaguacau caaaccccag      780

agucaauuua ucguggaccu cggcgcguau cuggaaaagg agagcauuua cuacgugaca      840

accaauugga aacacacugc aacacguuuc gccauaaagc cuauggagga uugaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9785
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9785
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacaccgc cgccgugcag      180

uacaacgugc uggagaagga cgacgacccc gccagccuga ccaucugggu gcccauguuc      240

cagagcagca ugcccgccga ccugcugauc aaggagcugg ccaacgugaa cauccuggug      300

aagcagauca gcacccccaa gggccccagc cugagaguga ugaucaacag cagaagcgcc      360

gugcuggccc agaugcccag caaguucacc aucugcgcca acgugagccu ggacgagaga      420

agcaagcugg ccuacgacgu gaccaccccc ugcgagauca aggccugcag ccugaccugc      480

cugaagagca agaacaugcu gaccaccgug aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu gugcgaguuc gagaacaucg ugaccagcaa gaaggugauc      600

auccccaccu accugagaag caucagcgug agaaacaagg accugaacac ccuggagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacagcggc      720

cugcugcugg ugaucaccgu gaccgacaac aagggcgccu ucaaguacau caagccccag      780

agccaguuca ucguggaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc caccagauuc gccaucaagc ccauggagga cugaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9786
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9786
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacggc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gccucccuga ccaucugggu gccuauguuc      240

caaucuagca ugccggcgga ucuucugauu aaggaacucg cuaacgugaa uauccugguc      300

aaacagauuu ccacacccaa ggggccuucu cuuagaguga ugaucaacag ccgguccgcc      360

guucuggccc agaugcccuc uaaauuuacc auuugcgcua augugagccu cgacgagcgc      420

uccaagcugg ccuaugaugu cacaaccccu ugugaaauca aggcuugcag ccugacaugu      480

cucaaaucua agaacaugcu gaccacggug aaagaccuua ccaugaagac acugaauccc      540

acccaugaua ucauugcccu cugcgaguuc gagaacaucg uuacauccaa aaaggugauu      600

aucccuaccu accugagaag cauuucuguc cggaauaagg accuuaacac gcuggaaaau      660

aucacaacca cagaguuuaa aaacgcgauu accaaugcca agaucauccc guauuccgga      720

cuccugcugg ugauuaccgu gacagauaac aaaggcgcuu ucaaguacau caaaccccag      780

agccaauuua uugucgaccu cggggccuau cuggaaaagg agucuaucua cuacguuacg      840

accaauugga aacacacagc uacccgcuuc gccauuaagc cuauggagga uugaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9787
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9787
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacguaaa caaacuacac gaaggaucca cauacacagc agcaguacaa      180

uacaacguac uagaaaaaga cgacgaccca gcaucuuuaa ccauaugggu accaauguuc      240

caaucaucaa ugccagcaga ccucuuaaua aaagaacuag caaacguaaa cauccuaguc      300

aaacaaauau caacacccaa aggaccaucc cucagaguaa ugaucaacuc aagaucagca      360

guacuagcac aaaugccauc aaaauucaca auaugcgcca acguuucuuu agacgaacga      420

ucaaaauuag ccuacgacgu aacaacaccc ugcgaaauaa aagcaugcuc acuaacaugc      480

cuaaaaucaa aaaacaugcu cacuacagua aaagaccuaa ccaugaaaac acucaaccca      540

acacacgaca uaauagcccu augcgaauuu gaaaacauag uaacaucaaa aaaaguaaua      600

aucccaacau acuuaagauc gaucucaguc agaaacaaag accuaaauac acucgaaaac      660

auaacaacaa cagaauuuaa aaacgcaaua acaaacgcaa aaauaauacc auacucagga      720

cuacuccuag uaauaacagu aacagacaac aaaggagcau ucaaauacau aaaaccacaa      780

ucacaauuca ucguagaccu cggagcauac cuagaaaaag aaucaauaua cuacguaaca      840

acaaacugga aacacaccgc cacaagauuc gcaauaaaac ccauggaaga cuaaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9788
<211>  1169
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9788
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa ccuacgucaa caaacuacac gaaggcucaa ccuacaccgc cgccguccaa      180

uacaacgucc ucgaaaaaga cgacgacccc gccucccuaa ccaucugggu ucccauguuc      240

caaucaucca ugcccgccga ccuccucaua aaagaacuag ccaacgucaa cauccuaguc      300

aaacaaauca gcacccccaa aggccccucc cuccgcguaa ugaucaacuc ccgcuccgcc      360

guccuagccc aaaugcccuc caaauuuaca aucugcgcca acgucucccu cgacgaacgc      420

ucaaaacucg ccuacgacgu caccacaccc ugcgaaauca aagccugcuc ccucaccugc      480

cucaaaagca aaaauaugcu aaccaccguc aaagaccuua ccaugaaaac ccucaacccc      540

acucacgaca ucauagcccu cugcgaauuu gaaaacaucg ucaccuccaa aaaagucauc      600

auccccacau accuccgcuc caucuccguc cgcaacaaag accucaacac ccucgaaaac      660

aucaccacca ccgaauuuaa aaacgccauc accaacgcca aaaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu uaccgacaac aaaggcgccu ucaaauacau caaaccccaa      780

ucccaauuca ucgucgaccu cggagccuac cuugaaaaag aguccaucua cuacgucacc      840

accaacugga aacacaccgc cacccgauuc gccaucaaac ccauggaaga cuaaggacua      900

guggaagcau uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu      960

uagaaggcua ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau     1020

uuuaaaaaau cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1140

caaaggcucu uuucagagcc accagaauu                                       1169


<210>  9789
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9789
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu gaacaagcuu      120

cacgaaggcu ccacauacac agcugcuguu caauacaaug ucuuagaaaa agacgaugac      180

ccugcaucac uuacaauaug ggugcccaug uuccaaucau cuaugccagc agauuuacuu      240

auaaaagaac uagcuaaugu caacauacua gugaaacaaa uauccacacc caagggaccu      300

ucacuaagag ucaugauaaa cucaagaagu gcagugcuag cacaaaugcc cagcaaauuu      360

accauaugcg cuaauguguc cuuggaugaa agaagcaaac uagcauauga uguaaccaca      420

cccugugaaa ucaaggcaug uagucuaaca ugccuaaaau caaaaaauau guugacuaca      480

guuaaagauc ucacuaugaa gacacucaac ccuacacaug auauuauugc uuuaugugaa      540

uuugaaaaca uaguaacauc aaaaaaaguc auaauaccaa cauaccuaag auccaucagu      600

gucagaaaua aagaucugaa cacacuugaa aauauaacaa ccacugaauu caaaaaugcu      660

aucacaaaug caaaaaucau cccuuacuca ggauuacuau uagucaucac agugacugac      720

aacaaaggag cauucaaaua cauaaagcca caaagucaau ucauaguaga ucuuggagcu      780

uaccuagaaa aagaaaguau auauuauguu accacaaauu ggaagcacac agcuacacga      840

uuugcaauca aacccaugga agauuaagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9790
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9790
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac ggccgccguc caguacaacg ugcucgagaa ggacgacgac      180

cccgcguccc ugaccaucug ggugccgaug uuccagagcu ccaugcccgc cgaccugcuc      240

aucaaggagc uggccaacgu caacauccug gugaagcaga ucagcacccc caaggggccc      300

ucccuccgcg ugaugaucaa cagccggucc gccguccugg cccagaugcc gagcaaguuc      360

accaucugcg cgaacguguc ccuggacgag cgcagcaagc ucgccuacga cgugacgacc      420

cccugcgaga ucaaggccug cucccugacc ugccucaaga gcaagaacau gcugaccacg      480

gucaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgugacguc caagaaggug aucaucccca ccuaccugcg gagcaucucc      600

guccgcaaca aggaccugaa cacccucgag aacaucacca cgaccgaguu caagaacgcg      660

aucaccaacg ccaagaucau cccguacagc ggccugcugc ucgugaucac cgugacggac      720

aacaaggggg ccuucaagua caucaagccc cagucccagu ucaucgucga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccacgcgg      840

uucgcgauca agcccaugga ggacugagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9791
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9791
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu caacaagcuc      120

cacgagggcu ccaccuacac cgccgccguc caguacaacg uccucgagaa ggacgacgac      180

cccgccuccc ucaccaucug gguccccaug uuccaguccu ccaugcccgc cgaccuccuc      240

aucaaggagc ucgccaacgu caacauccuc gucaagcaga ucuccacccc caagggcccc      300

ucccuccgcg ucaugaucaa cucccgcucc gccguccucg cccagaugcc cuccaaguuc      360

accaucugcg ccaacgucuc ccucgacgag cgcuccaagc ucgccuacga cgucaccacc      420

cccugcgaga ucaaggccug cucccucacc ugccucaagu ccaagaacau gcucaccacc      480

gucaaggacc ucaccaugaa gacccucaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgucaccuc caagaagguc aucaucccca ccuaccuccg cuccaucucc      600

guccgcaaca aggaccucaa cacccucgag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacucc ggccuccucc ucgucaucac cgucaccgac      720

aacaagggcg ccuucaagua caucaagccc cagucccagu ucaucgucga ccucggcgcc      780

uaccucgaga aggaguccau cuacuacguc accaccaacu ggaagcacac cgccacccgc      840

uucgccauca agcccaugga ggacugagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9792
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9792
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ugccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgcauccc uuacgaucug ggugccuaug uuccaaucuu caaugccagc cgaucuguug      240

auuaaggaau uagcgaacgu aaauauacug gugaaacaga ucaguacccc gaaggggccc      300

agccuaagag ucaugauuaa cuccaggucu gcugugcucg cccagaugcc uucgaaauuu      360

acaaucugcg caaauguuuc acuggacgag cggagcaaac uugccuauga ugugacuacc      420

ccaugugaaa uuaaggcuug cagucugaca uguuugaagu ccaagaacau gcucaccacu      480

gucaaagacc ugacaaugaa gacccugaau cccacgcaug auaucauagc acucugcgag      540

uucgagaaca ucgugacuuc uaaaaaggua auuaucccua ccuacuuacg cagcauuucc      600

guucgaaaua aggaccugaa cacacuugaa aauaucacua ccacagaguu uaaaaacgcc      660

auaaccaaug cuaagauuau cccauauuca ggauugcugc uagugauuac ggucacugau      720

aacaaaggug ccuucaagua caucaaaccc cagagucaau uuaucgugga ccucggcgcg      780

uaucuggaaa aggagagcau uuacuacgug acaaccaauu ggaaacacac ugcaacacgu      840

uucgccauaa agccuaugga ggauugagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9793
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9793
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac cgccgccgug caguacaacg ugcuggagaa ggacgacgac      180

cccgccagcc ugaccaucug ggugcccaug uuccagagca gcaugcccgc cgaccugcug      240

aucaaggagc uggccaacgu gaacauccug gugaagcaga ucagcacccc caagggcccc      300

agccugagag ugaugaucaa cagcagaagc gccgugcugg cccagaugcc cagcaaguuc      360

accaucugcg ccaacgugag ccuggacgag agaagcaagc uggccuacga cgugaccacc      420

cccugcgaga ucaaggccug cagccugacc ugccugaaga gcaagaacau gcugaccacc      480

gugaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccugugcgag      540

uucgagaaca ucgugaccag caagaaggug aucaucccca ccuaccugag aagcaucagc      600

gugagaaaca aggaccugaa cacccuggag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacagc ggccugcugc uggugaucac cgugaccgac      720

aacaagggcg ccuucaagua caucaagccc cagagccagu ucaucgugga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccaccaga      840

uucgccauca agcccaugga ggacugagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9794
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9794
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ggccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgccuccc ugaccaucug ggugccuaug uuccaaucua gcaugccggc ggaucuucug      240

auuaaggaac ucgcuaacgu gaauauccug gucaaacaga uuuccacacc caaggggccu      300

ucucuuagag ugaugaucaa cagccggucc gccguucugg cccagaugcc cucuaaauuu      360

accauuugcg cuaaugugag ccucgacgag cgcuccaagc uggccuauga ugucacaacc      420

ccuugugaaa ucaaggcuug cagccugaca ugucucaaau cuaagaacau gcugaccacg      480

gugaaagacc uuaccaugaa gacacugaau cccacccaug auaucauugc ccucugcgag      540

uucgagaaca ucguuacauc caaaaaggug auuaucccua ccuaccugag aagcauuucu      600

guccggaaua aggaccuuaa cacgcuggaa aauaucacaa ccacagaguu uaaaaacgcg      660

auuaccaaug ccaagaucau cccguauucc ggacuccugc uggugauuac cgugacagau      720

aacaaaggcg cuuucaagua caucaaaccc cagagccaau uuauugucga ccucggggcc      780

uaucuggaaa aggagucuau cuacuacguu acgaccaauu ggaaacacac agcuacccgc      840

uucgccauua agccuaugga ggauugagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9795
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9795
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu aaacaaacua      120

cacgaaggau ccacauacac agcagcagua caauacaacg uacuagaaaa agacgacgac      180

ccagcaucuu uaaccauaug gguaccaaug uuccaaucau caaugccagc agaccucuua      240

auaaaagaac uagcaaacgu aaacauccua gucaaacaaa uaucaacacc caaaggacca      300

ucccucagag uaaugaucaa cucaagauca gcaguacuag cacaaaugcc aucaaaauuc      360

acaauaugcg ccaacguuuc uuuagacgaa cgaucaaaau uagccuacga cguaacaaca      420

cccugcgaaa uaaaagcaug cucacuaaca ugccuaaaau caaaaaacau gcucacuaca      480

guaaaagacc uaaccaugaa aacacucaac ccaacacacg acauaauagc ccuaugcgaa      540

uuugaaaaca uaguaacauc aaaaaaagua auaaucccaa cauacuuaag aucgaucuca      600

gucagaaaca aagaccuaaa uacacucgaa aacauaacaa caacagaauu uaaaaacgca      660

auaacaaacg caaaaauaau accauacuca ggacuacucc uaguaauaac aguaacagac      720

aacaaaggag cauucaaaua cauaaaacca caaucacaau ucaucguaga ccucggagca      780

uaccuagaaa aagaaucaau auacuacgua acaacaaacu ggaaacacac cgccacaaga      840

uucgcaauaa aacccaugga agacuaagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9796
<211>  1146
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9796
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaccuacgu caacaaacua      120

cacgaaggcu caaccuacac cgccgccguc caauacaacg uccucgaaaa agacgacgac      180

cccgccuccc uaaccaucug gguucccaug uuccaaucau ccaugcccgc cgaccuccuc      240

auaaaagaac uagccaacgu caacauccua gucaaacaaa ucagcacccc caaaggcccc      300

ucccuccgcg uaaugaucaa cucccgcucc gccguccuag cccaaaugcc cuccaaauuu      360

acaaucugcg ccaacgucuc ccucgacgaa cgcucaaaac ucgccuacga cgucaccaca      420

cccugcgaaa ucaaagccug cucccucacc ugccucaaaa gcaaaaauau gcuaaccacc      480

gucaaagacc uuaccaugaa aacccucaac cccacucacg acaucauagc ccucugcgaa      540

uuugaaaaca ucgucaccuc caaaaaaguc aucaucccca cauaccuccg cuccaucucc      600

guccgcaaca aagaccucaa cacccucgaa aacaucacca ccaccgaauu uaaaaacgcc      660

aucaccaacg ccaaaaucau ccccuacucc ggccuccucc ucgucaucac cguuaccgac      720

aacaaaggcg ccuucaaaua caucaaaccc caaucccaau ucaucgucga ccucggagcc      780

uaccuugaaa aagaguccau cuacuacguc accaccaacu ggaaacacac cgccacccga      840

uucgccauca aacccaugga agacuaagga cuaguacugg cugcaucucc cuuuccucug      900

uccuccaucc uucucccagg auggugaagg gggaccuggu acccagugau ccccacccca      960

ggauccuaaa ucaugacuua ccugcuaaua aaaacucauu ggaaaaguga gaagaucuaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1140

agaauu                                                                1146


<210>  9797
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9797
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu gaacaagcuu      120

cacgaaggcu ccacauacac agcugcuguu caauacaaug ucuuagaaaa agacgaugac      180

ccugcaucac uuacaauaug ggugcccaug uuccaaucau cuaugccagc agauuuacuu      240

auaaaagaac uagcuaaugu caacauacua gugaaacaaa uauccacacc caagggaccu      300

ucacuaagag ucaugauaaa cucaagaagu gcagugcuag cacaaaugcc cagcaaauuu      360

accauaugcg cuaauguguc cuuggaugaa agaagcaaac uagcauauga uguaaccaca      420

cccugugaaa ucaaggcaug uagucuaaca ugccuaaaau caaaaaauau guugacuaca      480

guuaaagauc ucacuaugaa gacacucaac ccuacacaug auauuauugc uuuaugugaa      540

uuugaaaaca uaguaacauc aaaaaaaguc auaauaccaa cauaccuaag auccaucagu      600

gucagaaaua aagaucugaa cacacuugaa aauauaacaa ccacugaauu caaaaaugcu      660

aucacaaaug caaaaaucau cccuuacuca ggauuacuau uagucaucac agugacugac      720

aacaaaggag cauucaaaua cauaaagcca caaagucaau ucauaguaga ucuuggagcu      780

uaccuagaaa aagaaaguau auauuauguu accacaaauu ggaagcacac agcuacacga      840

uuugcaauca aacccaugga agauuaagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9798
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9798
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac ggccgccguc caguacaacg ugcucgagaa ggacgacgac      180

cccgcguccc ugaccaucug ggugccgaug uuccagagcu ccaugcccgc cgaccugcuc      240

aucaaggagc uggccaacgu caacauccug gugaagcaga ucagcacccc caaggggccc      300

ucccuccgcg ugaugaucaa cagccggucc gccguccugg cccagaugcc gagcaaguuc      360

accaucugcg cgaacguguc ccuggacgag cgcagcaagc ucgccuacga cgugacgacc      420

cccugcgaga ucaaggccug cucccugacc ugccucaaga gcaagaacau gcugaccacg      480

gucaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgugacguc caagaaggug aucaucccca ccuaccugcg gagcaucucc      600

guccgcaaca aggaccugaa cacccucgag aacaucacca cgaccgaguu caagaacgcg      660

aucaccaacg ccaagaucau cccguacagc ggccugcugc ucgugaucac cgugacggac      720

aacaaggggg ccuucaagua caucaagccc cagucccagu ucaucgucga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccacgcgg      840

uucgcgauca agcccaugga ggacugagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9799
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9799
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu caacaagcuc      120

cacgagggcu ccaccuacac cgccgccguc caguacaacg uccucgagaa ggacgacgac      180

cccgccuccc ucaccaucug gguccccaug uuccaguccu ccaugcccgc cgaccuccuc      240

aucaaggagc ucgccaacgu caacauccuc gucaagcaga ucuccacccc caagggcccc      300

ucccuccgcg ucaugaucaa cucccgcucc gccguccucg cccagaugcc cuccaaguuc      360

accaucugcg ccaacgucuc ccucgacgag cgcuccaagc ucgccuacga cgucaccacc      420

cccugcgaga ucaaggccug cucccucacc ugccucaagu ccaagaacau gcucaccacc      480

gucaaggacc ucaccaugaa gacccucaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgucaccuc caagaagguc aucaucccca ccuaccuccg cuccaucucc      600

guccgcaaca aggaccucaa cacccucgag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacucc ggccuccucc ucgucaucac cgucaccgac      720

aacaagggcg ccuucaagua caucaagccc cagucccagu ucaucgucga ccucggcgcc      780

uaccucgaga aggaguccau cuacuacguc accaccaacu ggaagcacac cgccacccgc      840

uucgccauca agcccaugga ggacugagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9800
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9800
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ugccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgcauccc uuacgaucug ggugccuaug uuccaaucuu caaugccagc cgaucuguug      240

auuaaggaau uagcgaacgu aaauauacug gugaaacaga ucaguacccc gaaggggccc      300

agccuaagag ucaugauuaa cuccaggucu gcugugcucg cccagaugcc uucgaaauuu      360

acaaucugcg caaauguuuc acuggacgag cggagcaaac uugccuauga ugugacuacc      420

ccaugugaaa uuaaggcuug cagucugaca uguuugaagu ccaagaacau gcucaccacu      480

gucaaagacc ugacaaugaa gacccugaau cccacgcaug auaucauagc acucugcgag      540

uucgagaaca ucgugacuuc uaaaaaggua auuaucccua ccuacuuacg cagcauuucc      600

guucgaaaua aggaccugaa cacacuugaa aauaucacua ccacagaguu uaaaaacgcc      660

auaaccaaug cuaagauuau cccauauuca ggauugcugc uagugauuac ggucacugau      720

aacaaaggug ccuucaagua caucaaaccc cagagucaau uuaucgugga ccucggcgcg      780

uaucuggaaa aggagagcau uuacuacgug acaaccaauu ggaaacacac ugcaacacgu      840

uucgccauaa agccuaugga ggauugagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9801
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9801
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac cgccgccgug caguacaacg ugcuggagaa ggacgacgac      180

cccgccagcc ugaccaucug ggugcccaug uuccagagca gcaugcccgc cgaccugcug      240

aucaaggagc uggccaacgu gaacauccug gugaagcaga ucagcacccc caagggcccc      300

agccugagag ugaugaucaa cagcagaagc gccgugcugg cccagaugcc cagcaaguuc      360

accaucugcg ccaacgugag ccuggacgag agaagcaagc uggccuacga cgugaccacc      420

cccugcgaga ucaaggccug cagccugacc ugccugaaga gcaagaacau gcugaccacc      480

gugaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccugugcgag      540

uucgagaaca ucgugaccag caagaaggug aucaucccca ccuaccugag aagcaucagc      600

gugagaaaca aggaccugaa cacccuggag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacagc ggccugcugc uggugaucac cgugaccgac      720

aacaagggcg ccuucaagua caucaagccc cagagccagu ucaucgugga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccaccaga      840

uucgccauca agcccaugga ggacugagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9802
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9802
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ggccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgccuccc ugaccaucug ggugccuaug uuccaaucua gcaugccggc ggaucuucug      240

auuaaggaac ucgcuaacgu gaauauccug gucaaacaga uuuccacacc caaggggccu      300

ucucuuagag ugaugaucaa cagccggucc gccguucugg cccagaugcc cucuaaauuu      360

accauuugcg cuaaugugag ccucgacgag cgcuccaagc uggccuauga ugucacaacc      420

ccuugugaaa ucaaggcuug cagccugaca ugucucaaau cuaagaacau gcugaccacg      480

gugaaagacc uuaccaugaa gacacugaau cccacccaug auaucauugc ccucugcgag      540

uucgagaaca ucguuacauc caaaaaggug auuaucccua ccuaccugag aagcauuucu      600

guccggaaua aggaccuuaa cacgcuggaa aauaucacaa ccacagaguu uaaaaacgcg      660

auuaccaaug ccaagaucau cccguauucc ggacuccugc uggugauuac cgugacagau      720

aacaaaggcg cuuucaagua caucaaaccc cagagccaau uuauugucga ccucggggcc      780

uaucuggaaa aggagucuau cuacuacguu acgaccaauu ggaaacacac agcuacccgc      840

uucgccauua agccuaugga ggauugagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9803
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9803
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu aaacaaacua      120

cacgaaggau ccacauacac agcagcagua caauacaacg uacuagaaaa agacgacgac      180

ccagcaucuu uaaccauaug gguaccaaug uuccaaucau caaugccagc agaccucuua      240

auaaaagaac uagcaaacgu aaacauccua gucaaacaaa uaucaacacc caaaggacca      300

ucccucagag uaaugaucaa cucaagauca gcaguacuag cacaaaugcc aucaaaauuc      360

acaauaugcg ccaacguuuc uuuagacgaa cgaucaaaau uagccuacga cguaacaaca      420

cccugcgaaa uaaaagcaug cucacuaaca ugccuaaaau caaaaaacau gcucacuaca      480

guaaaagacc uaaccaugaa aacacucaac ccaacacacg acauaauagc ccuaugcgaa      540

uuugaaaaca uaguaacauc aaaaaaagua auaaucccaa cauacuuaag aucgaucuca      600

gucagaaaca aagaccuaaa uacacucgaa aacauaacaa caacagaauu uaaaaacgca      660

auaacaaacg caaaaauaau accauacuca ggacuacucc uaguaauaac aguaacagac      720

aacaaaggag cauucaaaua cauaaaacca caaucacaau ucaucguaga ccucggagca      780

uaccuagaaa aagaaucaau auacuacgua acaacaaacu ggaaacacac cgccacaaga      840

uucgcaauaa aacccaugga agacuaagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9804
<211>  1142
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9804
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaccuacgu caacaaacua      120

cacgaaggcu caaccuacac cgccgccguc caauacaacg uccucgaaaa agacgacgac      180

cccgccuccc uaaccaucug gguucccaug uuccaaucau ccaugcccgc cgaccuccuc      240

auaaaagaac uagccaacgu caacauccua gucaaacaaa ucagcacccc caaaggcccc      300

ucccuccgcg uaaugaucaa cucccgcucc gccguccuag cccaaaugcc cuccaaauuu      360

acaaucugcg ccaacgucuc ccucgacgaa cgcucaaaac ucgccuacga cgucaccaca      420

cccugcgaaa ucaaagccug cucccucacc ugccucaaaa gcaaaaauau gcuaaccacc      480

gucaaagacc uuaccaugaa aacccucaac cccacucacg acaucauagc ccucugcgaa      540

uuugaaaaca ucgucaccuc caaaaaaguc aucaucccca cauaccuccg cuccaucucc      600

guccgcaaca aagaccucaa cacccucgaa aacaucacca ccaccgaauu uaaaaacgcc      660

aucaccaacg ccaaaaucau ccccuacucc ggccuccucc ucgucaucac cguuaccgac      720

aacaaaggcg ccuucaaaua caucaaaccc caaucccaau ucaucgucga ccucggagcc      780

uaccuugaaa aagaguccau cuacuacguc accaccaacu ggaaacacac cgccacccga      840

uucgccauca aacccaugga agacuaagga cuaguggaag cauuuuccug gcugauuaaa      900

agaaauuacu cagcuauggu caucuguucc uguuagaagg cuaugcagca uauuauauac      960

uaugcgcaug uuaugaaaug cauaauaaaa aauuuuaaaa aaucuaaaag aucuaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1080

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1140

uu                                                                    1142


<210>  9805
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9805
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acgugaacaa gcuucacgaa      120

ggcuccacau acacagcugc uguucaauac aaugucuuag aaaaagacga ugacccugca      180

ucacuuacaa uaugggugcc cauguuccaa ucaucuaugc cagcagauuu acuuauaaaa      240

gaacuagcua augucaacau acuagugaaa caaauaucca cacccaaggg accuucacua      300

agagucauga uaaacucaag aagugcagug cuagcacaaa ugcccagcaa auuuaccaua      360

ugcgcuaaug uguccuugga ugaaagaagc aaacuagcau augauguaac cacacccugu      420

gaaaucaagg cauguagucu aacaugccua aaaucaaaaa auauguugac uacaguuaaa      480

gaucucacua ugaagacacu caacccuaca caugauauua uugcuuuaug ugaauuugaa      540

aacauaguaa caucaaaaaa agucauaaua ccaacauacc uaagauccau cagugucaga      600

aauaaagauc ugaacacacu ugaaaauaua acaaccacug aauucaaaaa ugcuaucaca      660

aaugcaaaaa ucaucccuua cucaggauua cuauuaguca ucacagugac ugacaacaaa      720

ggagcauuca aauacauaaa gccacaaagu caauucauag uagaucuugg agcuuaccua      780

gaaaaagaaa guauauauua uguuaccaca aauuggaagc acacagcuac acgauuugca      840

aucaaaccca uggaagauua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9806
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9806
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acacggccgc cguccaguac aacgugcucg agaaggacga cgaccccgcg      180

ucccugacca ucugggugcc gauguuccag agcuccaugc ccgccgaccu gcucaucaag      240

gagcuggcca acgucaacau ccuggugaag cagaucagca cccccaaggg gcccucccuc      300

cgcgugauga ucaacagccg guccgccguc cuggcccaga ugccgagcaa guucaccauc      360

ugcgcgaacg ugucccugga cgagcgcagc aagcucgccu acgacgugac gacccccugc      420

gagaucaagg ccugcucccu gaccugccuc aagagcaaga acaugcugac cacggucaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguga cguccaagaa ggugaucauc cccaccuacc ugcggagcau cuccguccgc      600

aacaaggacc ugaacacccu cgagaacauc accacgaccg aguucaagaa cgcgaucacc      660

aacgccaaga ucaucccgua cagcggccug cugcucguga ucaccgugac ggacaacaag      720

ggggccuuca aguacaucaa gccccagucc caguucaucg ucgaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac gcgguucgcg      840

aucaagccca uggaggacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9807
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9807
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgucaacaa gcuccacgag      120

ggcuccaccu acaccgccgc cguccaguac aacguccucg agaaggacga cgaccccgcc      180

ucccucacca ucuggguccc cauguuccag uccuccaugc ccgccgaccu ccucaucaag      240

gagcucgcca acgucaacau ccucgucaag cagaucucca cccccaaggg ccccucccuc      300

cgcgucauga ucaacucccg cuccgccguc cucgcccaga ugcccuccaa guucaccauc      360

ugcgccaacg ucucccucga cgagcgcucc aagcucgccu acgacgucac cacccccugc      420

gagaucaagg ccugcucccu caccugccuc aaguccaaga acaugcucac caccgucaag      480

gaccucacca ugaagacccu caaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguca ccuccaagaa ggucaucauc cccaccuacc uccgcuccau cuccguccgc      600

aacaaggacc ucaacacccu cgagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cuccggccuc cuccucguca ucaccgucac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagucc caguucaucg ucgaccucgg cgccuaccuc      780

gagaaggagu ccaucuacua cgucaccacc aacuggaagc acaccgccac ccgcuucgcc      840

aucaagccca uggaggacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9808
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9808
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacugccgc uguccaguac aauguucucg agaaagacga ugaccccgca      180

ucccuuacga ucugggugcc uauguuccaa ucuucaaugc cagccgaucu guugauuaag      240

gaauuagcga acguaaauau acuggugaaa cagaucagua ccccgaaggg gcccagccua      300

agagucauga uuaacuccag gucugcugug cucgcccaga ugccuucgaa auuuacaauc      360

ugcgcaaaug uuucacugga cgagcggagc aaacuugccu augaugugac uaccccaugu      420

gaaauuaagg cuugcagucu gacauguuug aaguccaaga acaugcucac cacugucaaa      480

gaccugacaa ugaagacccu gaaucccacg caugauauca uagcacucug cgaguucgag      540

aacaucguga cuucuaaaaa gguaauuauc ccuaccuacu uacgcagcau uuccguucga      600

aauaaggacc ugaacacacu ugaaaauauc acuaccacag aguuuaaaaa cgccauaacc      660

aaugcuaaga uuaucccaua uucaggauug cugcuaguga uuacggucac ugauaacaaa      720

ggugccuuca aguacaucaa accccagagu caauuuaucg uggaccucgg cgcguaucug      780

gaaaaggaga gcauuuacua cgugacaacc aauuggaaac acacugcaac acguuucgcc      840

auaaagccua uggaggauug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9809
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9809
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acaccgccgc cgugcaguac aacgugcugg agaaggacga cgaccccgcc      180

agccugacca ucugggugcc cauguuccag agcagcaugc ccgccgaccu gcugaucaag      240

gagcuggcca acgugaacau ccuggugaag cagaucagca cccccaaggg ccccagccug      300

agagugauga ucaacagcag aagcgccgug cuggcccaga ugcccagcaa guucaccauc      360

ugcgccaacg ugagccugga cgagagaagc aagcuggccu acgacgugac cacccccugc      420

gagaucaagg ccugcagccu gaccugccug aagagcaaga acaugcugac caccgugaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccugug cgaguucgag      540

aacaucguga ccagcaagaa ggugaucauc cccaccuacc ugagaagcau cagcgugaga      600

aacaaggacc ugaacacccu ggagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cagcggccug cugcugguga ucaccgugac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagagc caguucaucg uggaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac cagauucgcc      840

aucaagccca uggaggacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9810
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9810
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacggccgc uguccaguac aauguucucg agaaagacga ugaccccgcc      180

ucccugacca ucugggugcc uauguuccaa ucuagcaugc cggcggaucu ucugauuaag      240

gaacucgcua acgugaauau ccuggucaaa cagauuucca cacccaaggg gccuucucuu      300

agagugauga ucaacagccg guccgccguu cuggcccaga ugcccucuaa auuuaccauu      360

ugcgcuaaug ugagccucga cgagcgcucc aagcuggccu augaugucac aaccccuugu      420

gaaaucaagg cuugcagccu gacaugucuc aaaucuaaga acaugcugac cacggugaaa      480

gaccuuacca ugaagacacu gaaucccacc caugauauca uugcccucug cgaguucgag      540

aacaucguua cauccaaaaa ggugauuauc ccuaccuacc ugagaagcau uucuguccgg      600

aauaaggacc uuaacacgcu ggaaaauauc acaaccacag aguuuaaaaa cgcgauuacc      660

aaugccaaga ucaucccgua uuccggacuc cugcugguga uuaccgugac agauaacaaa      720

ggcgcuuuca aguacaucaa accccagagc caauuuauug ucgaccucgg ggccuaucug      780

gaaaaggagu cuaucuacua cguuacgacc aauuggaaac acacagcuac ccgcuucgcc      840

auuaagccua uggaggauug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9811
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9811
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acguaaacaa acuacacgaa      120

ggauccacau acacagcagc aguacaauac aacguacuag aaaaagacga cgacccagca      180

ucuuuaacca uauggguacc aauguuccaa ucaucaaugc cagcagaccu cuuaauaaaa      240

gaacuagcaa acguaaacau ccuagucaaa caaauaucaa cacccaaagg accaucccuc      300

agaguaauga ucaacucaag aucagcagua cuagcacaaa ugccaucaaa auucacaaua      360

ugcgccaacg uuucuuuaga cgaacgauca aaauuagccu acgacguaac aacacccugc      420

gaaauaaaag caugcucacu aacaugccua aaaucaaaaa acaugcucac uacaguaaaa      480

gaccuaacca ugaaaacacu caacccaaca cacgacauaa uagcccuaug cgaauuugaa      540

aacauaguaa caucaaaaaa aguaauaauc ccaacauacu uaagaucgau cucagucaga      600

aacaaagacc uaaauacacu cgaaaacaua acaacaacag aauuuaaaaa cgcaauaaca      660

aacgcaaaaa uaauaccaua cucaggacua cuccuaguaa uaacaguaac agacaacaaa      720

ggagcauuca aauacauaaa accacaauca caauucaucg uagaccucgg agcauaccua      780

gaaaaagaau caauauacua cguaacaaca aacuggaaac acaccgccac aagauucgca      840

auaaaaccca uggaagacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9812
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9812
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaccu acgucaacaa acuacacgaa      120

ggcucaaccu acaccgccgc cguccaauac aacguccucg aaaaagacga cgaccccgcc      180

ucccuaacca ucuggguucc cauguuccaa ucauccaugc ccgccgaccu ccucauaaaa      240

gaacuagcca acgucaacau ccuagucaaa caaaucagca cccccaaagg ccccucccuc      300

cgcguaauga ucaacucccg cuccgccguc cuagcccaaa ugcccuccaa auuuacaauc      360

ugcgccaacg ucucccucga cgaacgcuca aaacucgccu acgacgucac cacacccugc      420

gaaaucaaag ccugcucccu caccugccuc aaaagcaaaa auaugcuaac caccgucaaa      480

gaccuuacca ugaaaacccu caaccccacu cacgacauca uagcccucug cgaauuugaa      540

aacaucguca ccuccaaaaa agucaucauc cccacauacc uccgcuccau cuccguccgc      600

aacaaagacc ucaacacccu cgaaaacauc accaccaccg aauuuaaaaa cgccaucacc      660

aacgccaaaa ucauccccua cuccggccuc cuccucguca ucaccguuac cgacaacaaa      720

ggcgccuuca aauacaucaa accccaaucc caauucaucg ucgaccucgg agccuaccuu      780

gaaaaagagu ccaucuacua cgucaccacc aacuggaaac acaccgccac ccgauucgcc      840

aucaaaccca uggaagacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu      900

uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  9813
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9813
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cgugaacaag      120

cuucacgaag gcuccacaua cacagcugcu guucaauaca augucuuaga aaaagacgau      180

gacccugcau cacuuacaau augggugccc auguuccaau caucuaugcc agcagauuua      240

cuuauaaaag aacuagcuaa ugucaacaua cuagugaaac aaauauccac acccaaggga      300

ccuucacuaa gagucaugau aaacucaaga agugcagugc uagcacaaau gcccagcaaa      360

uuuaccauau gcgcuaaugu guccuuggau gaaagaagca aacuagcaua ugauguaacc      420

acacccugug aaaucaaggc auguagucua acaugccuaa aaucaaaaaa uauguugacu      480

acaguuaaag aucucacuau gaagacacuc aacccuacac augauauuau ugcuuuaugu      540

gaauuugaaa acauaguaac aucaaaaaaa gucauaauac caacauaccu aagauccauc      600

agugucagaa auaaagaucu gaacacacuu gaaaauauaa caaccacuga auucaaaaau      660

gcuaucacaa augcaaaaau caucccuuac ucaggauuac uauuagucau cacagugacu      720

gacaacaaag gagcauucaa auacauaaag ccacaaaguc aauucauagu agaucuugga      780

gcuuaccuag aaaaagaaag uauauauuau guuaccacaa auuggaagca cacagcuaca      840

cgauuugcaa ucaaacccau ggaagauuaa ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9814
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9814
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua cacggccgcc guccaguaca acgugcucga gaaggacgac      180

gaccccgcgu cccugaccau cugggugccg auguuccaga gcuccaugcc cgccgaccug      240

cucaucaagg agcuggccaa cgucaacauc cuggugaagc agaucagcac ccccaagggg      300

cccucccucc gcgugaugau caacagccgg uccgccgucc uggcccagau gccgagcaag      360

uucaccaucu gcgcgaacgu gucccuggac gagcgcagca agcucgccua cgacgugacg      420

acccccugcg agaucaaggc cugcucccug accugccuca agagcaagaa caugcugacc      480

acggucaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgugac guccaagaag gugaucaucc ccaccuaccu gcggagcauc      600

uccguccgca acaaggaccu gaacacccuc gagaacauca ccacgaccga guucaagaac      660

gcgaucacca acgccaagau caucccguac agcggccugc ugcucgugau caccgugacg      720

gacaacaagg gggccuucaa guacaucaag ccccaguccc aguucaucgu cgaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacg      840

cgguucgcga ucaagcccau ggaggacuga ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9815
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9815
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgucaacaag      120

cuccacgagg gcuccaccua caccgccgcc guccaguaca acguccucga gaaggacgac      180

gaccccgccu cccucaccau cugggucccc auguuccagu ccuccaugcc cgccgaccuc      240

cucaucaagg agcucgccaa cgucaacauc cucgucaagc agaucuccac ccccaagggc      300

cccucccucc gcgucaugau caacucccgc uccgccgucc ucgcccagau gcccuccaag      360

uucaccaucu gcgccaacgu cucccucgac gagcgcucca agcucgccua cgacgucacc      420

acccccugcg agaucaaggc cugcucccuc accugccuca aguccaagaa caugcucacc      480

accgucaagg accucaccau gaagacccuc aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgucac cuccaagaag gucaucaucc ccaccuaccu ccgcuccauc      600

uccguccgca acaaggaccu caacacccuc gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac uccggccucc uccucgucau caccgucacc      720

gacaacaagg gcgccuucaa guacaucaag ccccaguccc aguucaucgu cgaccucggc      780

gccuaccucg agaaggaguc caucuacuac gucaccacca acuggaagca caccgccacc      840

cgcuucgcca ucaagcccau ggaggacuga ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9816
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9816
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacugccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgcau cccuuacgau cugggugccu auguuccaau cuucaaugcc agccgaucug      240

uugauuaagg aauuagcgaa cguaaauaua cuggugaaac agaucaguac cccgaagggg      300

cccagccuaa gagucaugau uaacuccagg ucugcugugc ucgcccagau gccuucgaaa      360

uuuacaaucu gcgcaaaugu uucacuggac gagcggagca aacuugccua ugaugugacu      420

accccaugug aaauuaaggc uugcagucug acauguuuga aguccaagaa caugcucacc      480

acugucaaag accugacaau gaagacccug aaucccacgc augauaucau agcacucugc      540

gaguucgaga acaucgugac uucuaaaaag guaauuaucc cuaccuacuu acgcagcauu      600

uccguucgaa auaaggaccu gaacacacuu gaaaauauca cuaccacaga guuuaaaaac      660

gccauaacca augcuaagau uaucccauau ucaggauugc ugcuagugau uacggucacu      720

gauaacaaag gugccuucaa guacaucaaa ccccagaguc aauuuaucgu ggaccucggc      780

gcguaucugg aaaaggagag cauuuacuac gugacaacca auuggaaaca cacugcaaca      840

cguuucgcca uaaagccuau ggaggauuga ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9817
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9817
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua caccgccgcc gugcaguaca acgugcugga gaaggacgac      180

gaccccgcca gccugaccau cugggugccc auguuccaga gcagcaugcc cgccgaccug      240

cugaucaagg agcuggccaa cgugaacauc cuggugaagc agaucagcac ccccaagggc      300

cccagccuga gagugaugau caacagcaga agcgccgugc uggcccagau gcccagcaag      360

uucaccaucu gcgccaacgu gagccuggac gagagaagca agcuggccua cgacgugacc      420

acccccugcg agaucaaggc cugcagccug accugccuga agagcaagaa caugcugacc      480

accgugaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccugugc      540

gaguucgaga acaucgugac cagcaagaag gugaucaucc ccaccuaccu gagaagcauc      600

agcgugagaa acaaggaccu gaacacccug gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac agcggccugc ugcuggugau caccgugacc      720

gacaacaagg gcgccuucaa guacaucaag ccccagagcc aguucaucgu ggaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacc      840

agauucgcca ucaagcccau ggaggacuga ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9818
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9818
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacggccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgccu cccugaccau cugggugccu auguuccaau cuagcaugcc ggcggaucuu      240

cugauuaagg aacucgcuaa cgugaauauc cuggucaaac agauuuccac acccaagggg      300

ccuucucuua gagugaugau caacagccgg uccgccguuc uggcccagau gcccucuaaa      360

uuuaccauuu gcgcuaaugu gagccucgac gagcgcucca agcuggccua ugaugucaca      420

accccuugug aaaucaaggc uugcagccug acaugucuca aaucuaagaa caugcugacc      480

acggugaaag accuuaccau gaagacacug aaucccaccc augauaucau ugcccucugc      540

gaguucgaga acaucguuac auccaaaaag gugauuaucc cuaccuaccu gagaagcauu      600

ucuguccgga auaaggaccu uaacacgcug gaaaauauca caaccacaga guuuaaaaac      660

gcgauuacca augccaagau caucccguau uccggacucc ugcuggugau uaccgugaca      720

gauaacaaag gcgcuuucaa guacaucaaa ccccagagcc aauuuauugu cgaccucggg      780

gccuaucugg aaaaggaguc uaucuacuac guuacgacca auuggaaaca cacagcuacc      840

cgcuucgcca uuaagccuau ggaggauuga ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9819
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9819
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cguaaacaaa      120

cuacacgaag gauccacaua cacagcagca guacaauaca acguacuaga aaaagacgac      180

gacccagcau cuuuaaccau auggguacca auguuccaau caucaaugcc agcagaccuc      240

uuaauaaaag aacuagcaaa cguaaacauc cuagucaaac aaauaucaac acccaaagga      300

ccaucccuca gaguaaugau caacucaaga ucagcaguac uagcacaaau gccaucaaaa      360

uucacaauau gcgccaacgu uucuuuagac gaacgaucaa aauuagccua cgacguaaca      420

acacccugcg aaauaaaagc augcucacua acaugccuaa aaucaaaaaa caugcucacu      480

acaguaaaag accuaaccau gaaaacacuc aacccaacac acgacauaau agcccuaugc      540

gaauuugaaa acauaguaac aucaaaaaaa guaauaaucc caacauacuu aagaucgauc      600

ucagucagaa acaaagaccu aaauacacuc gaaaacauaa caacaacaga auuuaaaaac      660

gcaauaacaa acgcaaaaau aauaccauac ucaggacuac uccuaguaau aacaguaaca      720

gacaacaaag gagcauucaa auacauaaaa ccacaaucac aauucaucgu agaccucgga      780

gcauaccuag aaaaagaauc aauauacuac guaacaacaa acuggaaaca caccgccaca      840

agauucgcaa uaaaacccau ggaagacuaa ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9820
<211>  1069
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9820
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaccua cgucaacaaa      120

cuacacgaag gcucaaccua caccgccgcc guccaauaca acguccucga aaaagacgac      180

gaccccgccu cccuaaccau cuggguuccc auguuccaau cauccaugcc cgccgaccuc      240

cucauaaaag aacuagccaa cgucaacauc cuagucaaac aaaucagcac ccccaaaggc      300

cccucccucc gcguaaugau caacucccgc uccgccgucc uagcccaaau gcccuccaaa      360

uuuacaaucu gcgccaacgu cucccucgac gaacgcucaa aacucgccua cgacgucacc      420

acacccugcg aaaucaaagc cugcucccuc accugccuca aaagcaaaaa uaugcuaacc      480

accgucaaag accuuaccau gaaaacccuc aaccccacuc acgacaucau agcccucugc      540

gaauuugaaa acaucgucac cuccaaaaaa gucaucaucc ccacauaccu ccgcuccauc      600

uccguccgca acaaagaccu caacacccuc gaaaacauca ccaccaccga auuuaaaaac      660

gccaucacca acgccaaaau cauccccuac uccggccucc uccucgucau caccguuacc      720

gacaacaaag gcgccuucaa auacaucaaa ccccaauccc aauucaucgu cgaccucgga      780

gccuaccuug aaaaagaguc caucuacuac gucaccacca acuggaaaca caccgccacc      840

cgauucgcca ucaaacccau ggaagacuaa ggacuagucc cuguucccag agcccacuuu      900

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1020

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1069


<210>  9821
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9821
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acgugaacaa gcuucacgaa      120

ggcuccacau acacagcugc uguucaauac aaugucuuag aaaaagacga ugacccugca      180

ucacuuacaa uaugggugcc cauguuccaa ucaucuaugc cagcagauuu acuuauaaaa      240

gaacuagcua augucaacau acuagugaaa caaauaucca cacccaaggg accuucacua      300

agagucauga uaaacucaag aagugcagug cuagcacaaa ugcccagcaa auuuaccaua      360

ugcgcuaaug uguccuugga ugaaagaagc aaacuagcau augauguaac cacacccugu      420

gaaaucaagg cauguagucu aacaugccua aaaucaaaaa auauguugac uacaguuaaa      480

gaucucacua ugaagacacu caacccuaca caugauauua uugcuuuaug ugaauuugaa      540

aacauaguaa caucaaaaaa agucauaaua ccaacauacc uaagauccau cagugucaga      600

aauaaagauc ugaacacacu ugaaaauaua acaaccacug aauucaaaaa ugcuaucaca      660

aaugcaaaaa ucaucccuua cucaggauua cuauuaguca ucacagugac ugacaacaaa      720

ggagcauuca aauacauaaa gccacaaagu caauucauag uagaucuugg agcuuaccua      780

gaaaaagaaa guauauauua uguuaccaca aauuggaagc acacagcuac acgauuugca      840

aucaaaccca uggaagauua aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9822
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9822
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acacggccgc cguccaguac aacgugcucg agaaggacga cgaccccgcg      180

ucccugacca ucugggugcc gauguuccag agcuccaugc ccgccgaccu gcucaucaag      240

gagcuggcca acgucaacau ccuggugaag cagaucagca cccccaaggg gcccucccuc      300

cgcgugauga ucaacagccg guccgccguc cuggcccaga ugccgagcaa guucaccauc      360

ugcgcgaacg ugucccugga cgagcgcagc aagcucgccu acgacgugac gacccccugc      420

gagaucaagg ccugcucccu gaccugccuc aagagcaaga acaugcugac cacggucaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguga cguccaagaa ggugaucauc cccaccuacc ugcggagcau cuccguccgc      600

aacaaggacc ugaacacccu cgagaacauc accacgaccg aguucaagaa cgcgaucacc      660

aacgccaaga ucaucccgua cagcggccug cugcucguga ucaccgugac ggacaacaag      720

ggggccuuca aguacaucaa gccccagucc caguucaucg ucgaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac gcgguucgcg      840

aucaagccca uggaggacug aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9823
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9823
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgucaacaa gcuccacgag      120

ggcuccaccu acaccgccgc cguccaguac aacguccucg agaaggacga cgaccccgcc      180

ucccucacca ucuggguccc cauguuccag uccuccaugc ccgccgaccu ccucaucaag      240

gagcucgcca acgucaacau ccucgucaag cagaucucca cccccaaggg ccccucccuc      300

cgcgucauga ucaacucccg cuccgccguc cucgcccaga ugcccuccaa guucaccauc      360

ugcgccaacg ucucccucga cgagcgcucc aagcucgccu acgacgucac cacccccugc      420

gagaucaagg ccugcucccu caccugccuc aaguccaaga acaugcucac caccgucaag      480

gaccucacca ugaagacccu caaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguca ccuccaagaa ggucaucauc cccaccuacc uccgcuccau cuccguccgc      600

aacaaggacc ucaacacccu cgagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cuccggccuc cuccucguca ucaccgucac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagucc caguucaucg ucgaccucgg cgccuaccuc      780

gagaaggagu ccaucuacua cgucaccacc aacuggaagc acaccgccac ccgcuucgcc      840

aucaagccca uggaggacug aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9824
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9824
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacugccgc uguccaguac aauguucucg agaaagacga ugaccccgca      180

ucccuuacga ucugggugcc uauguuccaa ucuucaaugc cagccgaucu guugauuaag      240

gaauuagcga acguaaauau acuggugaaa cagaucagua ccccgaaggg gcccagccua      300

agagucauga uuaacuccag gucugcugug cucgcccaga ugccuucgaa auuuacaauc      360

ugcgcaaaug uuucacugga cgagcggagc aaacuugccu augaugugac uaccccaugu      420

gaaauuaagg cuugcagucu gacauguuug aaguccaaga acaugcucac cacugucaaa      480

gaccugacaa ugaagacccu gaaucccacg caugauauca uagcacucug cgaguucgag      540

aacaucguga cuucuaaaaa gguaauuauc ccuaccuacu uacgcagcau uuccguucga      600

aauaaggacc ugaacacacu ugaaaauauc acuaccacag aguuuaaaaa cgccauaacc      660

aaugcuaaga uuaucccaua uucaggauug cugcuaguga uuacggucac ugauaacaaa      720

ggugccuuca aguacaucaa accccagagu caauuuaucg uggaccucgg cgcguaucug      780

gaaaaggaga gcauuuacua cgugacaacc aauuggaaac acacugcaac acguuucgcc      840

auaaagccua uggaggauug aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9825
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9825
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acaccgccgc cgugcaguac aacgugcugg agaaggacga cgaccccgcc      180

agccugacca ucugggugcc cauguuccag agcagcaugc ccgccgaccu gcugaucaag      240

gagcuggcca acgugaacau ccuggugaag cagaucagca cccccaaggg ccccagccug      300

agagugauga ucaacagcag aagcgccgug cuggcccaga ugcccagcaa guucaccauc      360

ugcgccaacg ugagccugga cgagagaagc aagcuggccu acgacgugac cacccccugc      420

gagaucaagg ccugcagccu gaccugccug aagagcaaga acaugcugac caccgugaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccugug cgaguucgag      540

aacaucguga ccagcaagaa ggugaucauc cccaccuacc ugagaagcau cagcgugaga      600

aacaaggacc ugaacacccu ggagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cagcggccug cugcugguga ucaccgugac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagagc caguucaucg uggaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac cagauucgcc      840

aucaagccca uggaggacug aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9826
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9826
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacggccgc uguccaguac aauguucucg agaaagacga ugaccccgcc      180

ucccugacca ucugggugcc uauguuccaa ucuagcaugc cggcggaucu ucugauuaag      240

gaacucgcua acgugaauau ccuggucaaa cagauuucca cacccaaggg gccuucucuu      300

agagugauga ucaacagccg guccgccguu cuggcccaga ugcccucuaa auuuaccauu      360

ugcgcuaaug ugagccucga cgagcgcucc aagcuggccu augaugucac aaccccuugu      420

gaaaucaagg cuugcagccu gacaugucuc aaaucuaaga acaugcugac cacggugaaa      480

gaccuuacca ugaagacacu gaaucccacc caugauauca uugcccucug cgaguucgag      540

aacaucguua cauccaaaaa ggugauuauc ccuaccuacc ugagaagcau uucuguccgg      600

aauaaggacc uuaacacgcu ggaaaauauc acaaccacag aguuuaaaaa cgcgauuacc      660

aaugccaaga ucaucccgua uuccggacuc cugcugguga uuaccgugac agauaacaaa      720

ggcgcuuuca aguacaucaa accccagagc caauuuauug ucgaccucgg ggccuaucug      780

gaaaaggagu cuaucuacua cguuacgacc aauuggaaac acacagcuac ccgcuucgcc      840

auuaagccua uggaggauug aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9827
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9827
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acguaaacaa acuacacgaa      120

ggauccacau acacagcagc aguacaauac aacguacuag aaaaagacga cgacccagca      180

ucuuuaacca uauggguacc aauguuccaa ucaucaaugc cagcagaccu cuuaauaaaa      240

gaacuagcaa acguaaacau ccuagucaaa caaauaucaa cacccaaagg accaucccuc      300

agaguaauga ucaacucaag aucagcagua cuagcacaaa ugccaucaaa auucacaaua      360

ugcgccaacg uuucuuuaga cgaacgauca aaauuagccu acgacguaac aacacccugc      420

gaaauaaaag caugcucacu aacaugccua aaaucaaaaa acaugcucac uacaguaaaa      480

gaccuaacca ugaaaacacu caacccaaca cacgacauaa uagcccuaug cgaauuugaa      540

aacauaguaa caucaaaaaa aguaauaauc ccaacauacu uaagaucgau cucagucaga      600

aacaaagacc uaaauacacu cgaaaacaua acaacaacag aauuuaaaaa cgcaauaaca      660

aacgcaaaaa uaauaccaua cucaggacua cuccuaguaa uaacaguaac agacaacaaa      720

ggagcauuca aauacauaaa accacaauca caauucaucg uagaccucgg agcauaccua      780

gaaaaagaau caauauacua cguaacaaca aacuggaaac acaccgccac aagauucgca      840

auaaaaccca uggaagacua aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9828
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9828
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaccu acgucaacaa acuacacgaa      120

ggcucaaccu acaccgccgc cguccaauac aacguccucg aaaaagacga cgaccccgcc      180

ucccuaacca ucuggguucc cauguuccaa ucauccaugc ccgccgaccu ccucauaaaa      240

gaacuagcca acgucaacau ccuagucaaa caaaucagca cccccaaagg ccccucccuc      300

cgcguaauga ucaacucccg cuccgccguc cuagcccaaa ugcccuccaa auuuacaauc      360

ugcgccaacg ucucccucga cgaacgcuca aaacucgccu acgacgucac cacacccugc      420

gaaaucaaag ccugcucccu caccugccuc aaaagcaaaa auaugcuaac caccgucaaa      480

gaccuuacca ugaaaacccu caaccccacu cacgacauca uagcccucug cgaauuugaa      540

aacaucguca ccuccaaaaa agucaucauc cccacauacc uccgcuccau cuccguccgc      600

aacaaagacc ucaacacccu cgaaaacauc accaccaccg aauuuaaaaa cgccaucacc      660

aacgccaaaa ucauccccua cuccggccuc cuccucguca ucaccguuac cgacaacaaa      720

ggcgccuuca aauacaucaa accccaaucc caauucaucg ucgaccucgg agccuaccuu      780

gaaaaagagu ccaucuacua cgucaccacc aacuggaaac acaccgccac ccgauucgcc      840

aucaaaccca uggaagacua aggacuagua auaaggaaac uguaugaaug ucugugggca      900

ggaagugaag agauccuucu guaaagguuu uuggaauuau gucugcugaa uaauaaacuu      960

uuuugaaaua auaaaucugg uagaaaaaug agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  9829
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9829
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguga acaagcuuca cgaaggcucc acauacacag cugcuguuca auacaauguc      240

uuagaaaaag acgaugaccc ugcaucacuu acaauauggg ugcccauguu ccaaucaucu      300

augccagcag auuuacuuau aaaagaacua gcuaauguca acauacuagu gaaacaaaua      360

uccacaccca agggaccuuc acuaagaguc augauaaacu caagaagugc agugcuagca      420

caaaugccca gcaaauuuac cauaugcgcu aauguguccu uggaugaaag aagcaaacua      480

gcauaugaug uaaccacacc cugugaaauc aaggcaugua gucuaacaug ccuaaaauca      540

aaaaauaugu ugacuacagu uaaagaucuc acuaugaaga cacucaaccc uacacaugau      600

auuauugcuu uaugugaauu ugaaaacaua guaacaucaa aaaaagucau aauaccaaca      660

uaccuaagau ccaucagugu cagaaauaaa gaucugaaca cacuugaaaa uauaacaacc      720

acugaauuca aaaaugcuau cacaaaugca aaaaucaucc cuuacucagg auuacuauua      780

gucaucacag ugacugacaa caaaggagca uucaaauaca uaaagccaca aagucaauuc      840

auaguagauc uuggagcuua ccuagaaaaa gaaaguauau auuauguuac cacaaauugg      900

aagcacacag cuacacgauu ugcaaucaaa cccauggaag auuaaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9830
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9830
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacacgg ccgccgucca guacaacgug      240

cucgagaagg acgacgaccc cgcgucccug accaucuggg ugccgauguu ccagagcucc      300

augcccgccg accugcucau caaggagcug gccaacguca acauccuggu gaagcagauc      360

agcaccccca aggggcccuc ccuccgcgug augaucaaca gccgguccgc cguccuggcc      420

cagaugccga gcaaguucac caucugcgcg aacguguccc uggacgagcg cagcaagcuc      480

gccuacgacg ugacgacccc cugcgagauc aaggccugcu cccugaccug ccucaagagc      540

aagaacaugc ugaccacggu caaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gugacgucca agaaggugau cauccccacc      660

uaccugcgga gcaucuccgu ccgcaacaag gaccugaaca cccucgagaa caucaccacg      720

accgaguuca agaacgcgau caccaacgcc aagaucaucc cguacagcgg ccugcugcuc      780

gugaucaccg ugacggacaa caagggggcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccacgcgguu cgcgaucaag cccauggagg acugaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9831
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9831
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguca acaagcucca cgagggcucc accuacaccg ccgccgucca guacaacguc      240

cucgagaagg acgacgaccc cgccucccuc accaucuggg uccccauguu ccaguccucc      300

augcccgccg accuccucau caaggagcuc gccaacguca acauccucgu caagcagauc      360

uccaccccca agggccccuc ccuccgcguc augaucaacu cccgcuccgc cguccucgcc      420

cagaugcccu ccaaguucac caucugcgcc aacgucuccc ucgacgagcg cuccaagcuc      480

gccuacgacg ucaccacccc cugcgagauc aaggccugcu cccucaccug ccucaagucc      540

aagaacaugc ucaccaccgu caaggaccuc accaugaaga cccucaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gucaccucca agaaggucau cauccccacc      660

uaccuccgcu ccaucuccgu ccgcaacaag gaccucaaca cccucgagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg ucaccgacaa caagggcgcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ucggcgccua ccucgagaag gaguccaucu acuacgucac caccaacugg      900

aagcacaccg ccacccgcuu cgccaucaag cccauggagg acugaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9832
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9832
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacug ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgcaucccuu acgaucuggg ugccuauguu ccaaucuuca      300

augccagccg aucuguugau uaaggaauua gcgaacguaa auauacuggu gaaacagauc      360

aguaccccga aggggcccag ccuaagaguc augauuaacu ccaggucugc ugugcucgcc      420

cagaugccuu cgaaauuuac aaucugcgca aauguuucac uggacgagcg gagcaaacuu      480

gccuaugaug ugacuacccc augugaaauu aaggcuugca gucugacaug uuugaagucc      540

aagaacaugc ucaccacugu caaagaccug acaaugaaga cccugaaucc cacgcaugau      600

aucauagcac ucugcgaguu cgagaacauc gugacuucua aaaagguaau uaucccuacc      660

uacuuacgca gcauuuccgu ucgaaauaag gaccugaaca cacuugaaaa uaucacuacc      720

acagaguuua aaaacgccau aaccaaugcu aagauuaucc cauauucagg auugcugcua      780

gugauuacgg ucacugauaa caaaggugcc uucaaguaca ucaaacccca gagucaauuu      840

aucguggacc ucggcgcgua ucuggaaaag gagagcauuu acuacgugac aaccaauugg      900

aaacacacug caacacguuu cgccauaaag ccuauggagg auugaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9833
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9833
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacaccg ccgccgugca guacaacgug      240

cuggagaagg acgacgaccc cgccagccug accaucuggg ugcccauguu ccagagcagc      300

augcccgccg accugcugau caaggagcug gccaacguga acauccuggu gaagcagauc      360

agcaccccca agggccccag ccugagagug augaucaaca gcagaagcgc cgugcuggcc      420

cagaugccca gcaaguucac caucugcgcc aacgugagcc uggacgagag aagcaagcug      480

gccuacgacg ugaccacccc cugcgagauc aaggccugca gccugaccug ccugaagagc      540

aagaacaugc ugaccaccgu gaaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ugugcgaguu cgagaacauc gugaccagca agaaggugau cauccccacc      660

uaccugagaa gcaucagcgu gagaaacaag gaccugaaca cccuggagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacagcgg ccugcugcug      780

gugaucaccg ugaccgacaa caagggcgcc uucaaguaca ucaagcccca gagccaguuc      840

aucguggacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccaccagauu cgccaucaag cccauggagg acugaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9834
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9834
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacgg ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgccucccug accaucuggg ugccuauguu ccaaucuagc      300

augccggcgg aucuucugau uaaggaacuc gcuaacguga auauccuggu caaacagauu      360

uccacaccca aggggccuuc ucuuagagug augaucaaca gccgguccgc cguucuggcc      420

cagaugcccu cuaaauuuac cauuugcgcu aaugugagcc ucgacgagcg cuccaagcug      480

gccuaugaug ucacaacccc uugugaaauc aaggcuugca gccugacaug ucucaaaucu      540

aagaacaugc ugaccacggu gaaagaccuu accaugaaga cacugaaucc cacccaugau      600

aucauugccc ucugcgaguu cgagaacauc guuacaucca aaaaggugau uaucccuacc      660

uaccugagaa gcauuucugu ccggaauaag gaccuuaaca cgcuggaaaa uaucacaacc      720

acagaguuua aaaacgcgau uaccaaugcc aagaucaucc cguauuccgg acuccugcug      780

gugauuaccg ugacagauaa caaaggcgcu uucaaguaca ucaaacccca gagccaauuu      840

auugucgacc ucggggccua ucuggaaaag gagucuaucu acuacguuac gaccaauugg      900

aaacacacag cuacccgcuu cgccauuaag ccuauggagg auugaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9835
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9835
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguaa acaaacuaca cgaaggaucc acauacacag cagcaguaca auacaacgua      240

cuagaaaaag acgacgaccc agcaucuuua accauauggg uaccaauguu ccaaucauca      300

augccagcag accucuuaau aaaagaacua gcaaacguaa acauccuagu caaacaaaua      360

ucaacaccca aaggaccauc ccucagagua augaucaacu caagaucagc aguacuagca      420

caaaugccau caaaauucac aauaugcgcc aacguuucuu uagacgaacg aucaaaauua      480

gccuacgacg uaacaacacc cugcgaaaua aaagcaugcu cacuaacaug ccuaaaauca      540

aaaaacaugc ucacuacagu aaaagaccua accaugaaaa cacucaaccc aacacacgac      600

auaauagccc uaugcgaauu ugaaaacaua guaacaucaa aaaaaguaau aaucccaaca      660

uacuuaagau cgaucucagu cagaaacaaa gaccuaaaua cacucgaaaa cauaacaaca      720

acagaauuua aaaacgcaau aacaaacgca aaaauaauac cauacucagg acuacuccua      780

guaauaacag uaacagacaa caaaggagca uucaaauaca uaaaaccaca aucacaauuc      840

aucguagacc ucggagcaua ccuagaaaaa gaaucaauau acuacguaac aacaaacugg      900

aaacacaccg ccacaagauu cgcaauaaaa cccauggaag acuaaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9836
<211>  1440
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9836
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

accuacguca acaaacuaca cgaaggcuca accuacaccg ccgccgucca auacaacguc      240

cucgaaaaag acgacgaccc cgccucccua accaucuggg uucccauguu ccaaucaucc      300

augcccgccg accuccucau aaaagaacua gccaacguca acauccuagu caaacaaauc      360

agcaccccca aaggccccuc ccuccgcgua augaucaacu cccgcuccgc cguccuagcc      420

caaaugcccu ccaaauuuac aaucugcgcc aacgucuccc ucgacgaacg cucaaaacuc      480

gccuacgacg ucaccacacc cugcgaaauc aaagccugcu cccucaccug ccucaaaagc      540

aaaaauaugc uaaccaccgu caaagaccuu accaugaaaa cccucaaccc cacucacgac      600

aucauagccc ucugcgaauu ugaaaacauc gucaccucca aaaaagucau cauccccaca      660

uaccuccgcu ccaucuccgu ccgcaacaaa gaccucaaca cccucgaaaa caucaccacc      720

accgaauuua aaaacgccau caccaacgcc aaaaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg uuaccgacaa caaaggcgcc uucaaauaca ucaaacccca aucccaauuc      840

aucgucgacc ucggagccua ccuugaaaaa gaguccaucu acuacgucac caccaacugg      900

aaacacaccg ccacccgauu cgccaucaaa cccauggaag acuaaggacu agugaaggga      960

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa     1020

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu     1080

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1140

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1200

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1260

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1380

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1440


<210>  9837
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9837
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg ugaacaagcu ucacgaaggc uccacauaca      120

cagcugcugu ucaauacaau gucuuagaaa aagacgauga cccugcauca cuuacaauau      180

gggugcccau guuccaauca ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug      240

ucaacauacu agugaaacaa auauccacac ccaagggacc uucacuaaga gucaugauaa      300

acucaagaag ugcagugcua gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu      360

ccuuggauga aagaagcaaa cuagcauaug auguaaccac acccugugaa aucaaggcau      420

guagucuaac augccuaaaa ucaaaaaaua uguugacuac aguuaaagau cucacuauga      480

agacacucaa cccuacacau gauauuauug cuuuauguga auuugaaaac auaguaacau      540

caaaaaaagu cauaauacca acauaccuaa gauccaucag ugucagaaau aaagaucuga      600

acacacuuga aaauauaaca accacugaau ucaaaaaugc uaucacaaau gcaaaaauca      660

ucccuuacuc aggauuacua uuagucauca cagugacuga caacaaagga gcauucaaau      720

acauaaagcc acaaagucaa uucauaguag aucuuggagc uuaccuagaa aaagaaagua      780

uauauuaugu uaccacaaau uggaagcaca cagcuacacg auuugcaauc aaacccaugg      840

aagauuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9838
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9838
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

cggccgccgu ccaguacaac gugcucgaga aggacgacga ccccgcgucc cugaccaucu      180

gggugccgau guuccagagc uccaugcccg ccgaccugcu caucaaggag cuggccaacg      240

ucaacauccu ggugaagcag aucagcaccc ccaaggggcc cucccuccgc gugaugauca      300

acagccgguc cgccguccug gcccagaugc cgagcaaguu caccaucugc gcgaacgugu      360

cccuggacga gcgcagcaag cucgccuacg acgugacgac ccccugcgag aucaaggccu      420

gcucccugac cugccucaag agcaagaaca ugcugaccac ggucaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgugacgu      540

ccaagaaggu gaucaucccc accuaccugc ggagcaucuc cguccgcaac aaggaccuga      600

acacccucga gaacaucacc acgaccgagu ucaagaacgc gaucaccaac gccaagauca      660

ucccguacag cggccugcug cucgugauca ccgugacgga caacaagggg gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccacgcg guucgcgauc aagcccaugg      840

aggacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9839
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9839
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ucaacaagcu ccacgagggc uccaccuaca      120

ccgccgccgu ccaguacaac guccucgaga aggacgacga ccccgccucc cucaccaucu      180

ggguccccau guuccagucc uccaugcccg ccgaccuccu caucaaggag cucgccaacg      240

ucaacauccu cgucaagcag aucuccaccc ccaagggccc cucccuccgc gucaugauca      300

acucccgcuc cgccguccuc gcccagaugc ccuccaaguu caccaucugc gccaacgucu      360

cccucgacga gcgcuccaag cucgccuacg acgucaccac ccccugcgag aucaaggccu      420

gcucccucac cugccucaag uccaagaaca ugcucaccac cgucaaggac cucaccauga      480

agacccucaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgucaccu      540

ccaagaaggu caucaucccc accuaccucc gcuccaucuc cguccgcaac aaggaccuca      600

acacccucga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacuc cggccuccuc cucgucauca ccgucaccga caacaagggc gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accucggcgc cuaccucgag aaggagucca      780

ucuacuacgu caccaccaac uggaagcaca ccgccacccg cuucgccauc aagcccaugg      840

aggacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9840
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9840
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cugccgcugu ccaguacaau guucucgaga aagacgauga ccccgcaucc cuuacgaucu      180

gggugccuau guuccaaucu ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg      240

uaaauauacu ggugaaacag aucaguaccc cgaaggggcc cagccuaaga gucaugauua      300

acuccagguc ugcugugcuc gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu      360

cacuggacga gcggagcaaa cuugccuaug augugacuac cccaugugaa auuaaggcuu      420

gcagucugac auguuugaag uccaagaaca ugcucaccac ugucaaagac cugacaauga      480

agacccugaa ucccacgcau gauaucauag cacucugcga guucgagaac aucgugacuu      540

cuaaaaaggu aauuaucccu accuacuuac gcagcauuuc cguucgaaau aaggaccuga      600

acacacuuga aaauaucacu accacagagu uuaaaaacgc cauaaccaau gcuaagauua      660

ucccauauuc aggauugcug cuagugauua cggucacuga uaacaaaggu gccuucaagu      720

acaucaaacc ccagagucaa uuuaucgugg accucggcgc guaucuggaa aaggagagca      780

uuuacuacgu gacaaccaau uggaaacaca cugcaacacg uuucgccaua aagccuaugg      840

aggauugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9841
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9841
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

ccgccgccgu gcaguacaac gugcuggaga aggacgacga ccccgccagc cugaccaucu      180

gggugcccau guuccagagc agcaugcccg ccgaccugcu gaucaaggag cuggccaacg      240

ugaacauccu ggugaagcag aucagcaccc ccaagggccc cagccugaga gugaugauca      300

acagcagaag cgccgugcug gcccagaugc ccagcaaguu caccaucugc gccaacguga      360

gccuggacga gagaagcaag cuggccuacg acgugaccac ccccugcgag aucaaggccu      420

gcagccugac cugccugaag agcaagaaca ugcugaccac cgugaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccugugcga guucgagaac aucgugacca      540

gcaagaaggu gaucaucccc accuaccuga gaagcaucag cgugagaaac aaggaccuga      600

acacccugga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacag cggccugcug cuggugauca ccgugaccga caacaagggc gccuucaagu      720

acaucaagcc ccagagccag uucaucgugg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccaccag auucgccauc aagcccaugg      840

aggacugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9842
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9842
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cggccgcugu ccaguacaau guucucgaga aagacgauga ccccgccucc cugaccaucu      180

gggugccuau guuccaaucu agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg      240

ugaauauccu ggucaaacag auuuccacac ccaaggggcc uucucuuaga gugaugauca      300

acagccgguc cgccguucug gcccagaugc ccucuaaauu uaccauuugc gcuaauguga      360

gccucgacga gcgcuccaag cuggccuaug augucacaac cccuugugaa aucaaggcuu      420

gcagccugac augucucaaa ucuaagaaca ugcugaccac ggugaaagac cuuaccauga      480

agacacugaa ucccacccau gauaucauug cccucugcga guucgagaac aucguuacau      540

ccaaaaaggu gauuaucccu accuaccuga gaagcauuuc uguccggaau aaggaccuua      600

acacgcugga aaauaucaca accacagagu uuaaaaacgc gauuaccaau gccaagauca      660

ucccguauuc cggacuccug cuggugauua ccgugacaga uaacaaaggc gcuuucaagu      720

acaucaaacc ccagagccaa uuuauugucg accucggggc cuaucuggaa aaggagucua      780

ucuacuacgu uacgaccaau uggaaacaca cagcuacccg cuucgccauu aagccuaugg      840

aggauugagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9843
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9843
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg uaaacaaacu acacgaagga uccacauaca      120

cagcagcagu acaauacaac guacuagaaa aagacgacga cccagcaucu uuaaccauau      180

ggguaccaau guuccaauca ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg      240

uaaacauccu agucaaacaa auaucaacac ccaaaggacc aucccucaga guaaugauca      300

acucaagauc agcaguacua gcacaaaugc caucaaaauu cacaauaugc gccaacguuu      360

cuuuagacga acgaucaaaa uuagccuacg acguaacaac acccugcgaa auaaaagcau      420

gcucacuaac augccuaaaa ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga      480

aaacacucaa cccaacacac gacauaauag cccuaugcga auuugaaaac auaguaacau      540

caaaaaaagu aauaauccca acauacuuaa gaucgaucuc agucagaaac aaagaccuaa      600

auacacucga aaacauaaca acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa      660

uaccauacuc aggacuacuc cuaguaauaa caguaacaga caacaaagga gcauucaaau      720

acauaaaacc acaaucacaa uucaucguag accucggagc auaccuagaa aaagaaucaa      780

uauacuacgu aacaacaaac uggaaacaca ccgccacaag auucgcaaua aaacccaugg      840

aagacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9844
<211>  1123
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9844
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca      120

ccgccgccgu ccaauacaac guccucgaaa aagacgacga ccccgccucc cuaaccaucu      180

ggguucccau guuccaauca uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg      240

ucaacauccu agucaaacaa aucagcaccc ccaaaggccc cucccuccgc guaaugauca      300

acucccgcuc cgccguccua gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu      360

cccucgacga acgcucaaaa cucgccuacg acgucaccac acccugcgaa aucaaagccu      420

gcucccucac cugccucaaa agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga      480

aaacccucaa ccccacucac gacaucauag cccucugcga auuugaaaac aucgucaccu      540

ccaaaaaagu caucaucccc acauaccucc gcuccaucuc cguccgcaac aaagaccuca      600

acacccucga aaacaucacc accaccgaau uuaaaaacgc caucaccaac gccaaaauca      660

uccccuacuc cggccuccuc cucgucauca ccguuaccga caacaaaggc gccuucaaau      720

acaucaaacc ccaaucccaa uucaucgucg accucggagc cuaccuugaa aaagagucca      780

ucuacuacgu caccaccaac uggaaacaca ccgccacccg auucgccauc aaacccaugg      840

aagacuaagg acuaguggaa gcauuuuccu ggcugauuaa aagaaauuac ucagcuaugg      900

ucaucuguuc cuguuagaag gcuaugcagc auauuauaua cuaugcgcau guuaugaaau      960

gcauaauaaa aaauuuuaaa aaaucuaaaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1080

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1123


<210>  9845
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9845
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguga acaagcuuca cgaaggcucc acauacacag cugcuguuca auacaauguc      240

uuagaaaaag acgaugaccc ugcaucacuu acaauauggg ugcccauguu ccaaucaucu      300

augccagcag auuuacuuau aaaagaacua gcuaauguca acauacuagu gaaacaaaua      360

uccacaccca agggaccuuc acuaagaguc augauaaacu caagaagugc agugcuagca      420

caaaugccca gcaaauuuac cauaugcgcu aauguguccu uggaugaaag aagcaaacua      480

gcauaugaug uaaccacacc cugugaaauc aaggcaugua gucuaacaug ccuaaaauca      540

aaaaauaugu ugacuacagu uaaagaucuc acuaugaaga cacucaaccc uacacaugau      600

auuauugcuu uaugugaauu ugaaaacaua guaacaucaa aaaaagucau aauaccaaca      660

uaccuaagau ccaucagugu cagaaauaaa gaucugaaca cacuugaaaa uauaacaacc      720

acugaauuca aaaaugcuau cacaaaugca aaaaucaucc cuuacucagg auuacuauua      780

gucaucacag ugacugacaa caaaggagca uucaaauaca uaaagccaca aagucaauuc      840

auaguagauc uuggagcuua ccuagaaaaa gaaaguauau auuauguuac cacaaauugg      900

aagcacacag cuacacgauu ugcaaucaaa cccauggaag auuaaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9846
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9846
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacacgg ccgccgucca guacaacgug      240

cucgagaagg acgacgaccc cgcgucccug accaucuggg ugccgauguu ccagagcucc      300

augcccgccg accugcucau caaggagcug gccaacguca acauccuggu gaagcagauc      360

agcaccccca aggggcccuc ccuccgcgug augaucaaca gccgguccgc cguccuggcc      420

cagaugccga gcaaguucac caucugcgcg aacguguccc uggacgagcg cagcaagcuc      480

gccuacgacg ugacgacccc cugcgagauc aaggccugcu cccugaccug ccucaagagc      540

aagaacaugc ugaccacggu caaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gugacgucca agaaggugau cauccccacc      660

uaccugcgga gcaucuccgu ccgcaacaag gaccugaaca cccucgagaa caucaccacg      720

accgaguuca agaacgcgau caccaacgcc aagaucaucc cguacagcgg ccugcugcuc      780

gugaucaccg ugacggacaa caagggggcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccacgcgguu cgcgaucaag cccauggagg acugaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9847
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9847
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguca acaagcucca cgagggcucc accuacaccg ccgccgucca guacaacguc      240

cucgagaagg acgacgaccc cgccucccuc accaucuggg uccccauguu ccaguccucc      300

augcccgccg accuccucau caaggagcuc gccaacguca acauccucgu caagcagauc      360

uccaccccca agggccccuc ccuccgcguc augaucaacu cccgcuccgc cguccucgcc      420

cagaugcccu ccaaguucac caucugcgcc aacgucuccc ucgacgagcg cuccaagcuc      480

gccuacgacg ucaccacccc cugcgagauc aaggccugcu cccucaccug ccucaagucc      540

aagaacaugc ucaccaccgu caaggaccuc accaugaaga cccucaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gucaccucca agaaggucau cauccccacc      660

uaccuccgcu ccaucuccgu ccgcaacaag gaccucaaca cccucgagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg ucaccgacaa caagggcgcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ucggcgccua ccucgagaag gaguccaucu acuacgucac caccaacugg      900

aagcacaccg ccacccgcuu cgccaucaag cccauggagg acugaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9848
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9848
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacug ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgcaucccuu acgaucuggg ugccuauguu ccaaucuuca      300

augccagccg aucuguugau uaaggaauua gcgaacguaa auauacuggu gaaacagauc      360

aguaccccga aggggcccag ccuaagaguc augauuaacu ccaggucugc ugugcucgcc      420

cagaugccuu cgaaauuuac aaucugcgca aauguuucac uggacgagcg gagcaaacuu      480

gccuaugaug ugacuacccc augugaaauu aaggcuugca gucugacaug uuugaagucc      540

aagaacaugc ucaccacugu caaagaccug acaaugaaga cccugaaucc cacgcaugau      600

aucauagcac ucugcgaguu cgagaacauc gugacuucua aaaagguaau uaucccuacc      660

uacuuacgca gcauuuccgu ucgaaauaag gaccugaaca cacuugaaaa uaucacuacc      720

acagaguuua aaaacgccau aaccaaugcu aagauuaucc cauauucagg auugcugcua      780

gugauuacgg ucacugauaa caaaggugcc uucaaguaca ucaaacccca gagucaauuu      840

aucguggacc ucggcgcgua ucuggaaaag gagagcauuu acuacgugac aaccaauugg      900

aaacacacug caacacguuu cgccauaaag ccuauggagg auugaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9849
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9849
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacaccg ccgccgugca guacaacgug      240

cuggagaagg acgacgaccc cgccagccug accaucuggg ugcccauguu ccagagcagc      300

augcccgccg accugcugau caaggagcug gccaacguga acauccuggu gaagcagauc      360

agcaccccca agggccccag ccugagagug augaucaaca gcagaagcgc cgugcuggcc      420

cagaugccca gcaaguucac caucugcgcc aacgugagcc uggacgagag aagcaagcug      480

gccuacgacg ugaccacccc cugcgagauc aaggccugca gccugaccug ccugaagagc      540

aagaacaugc ugaccaccgu gaaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ugugcgaguu cgagaacauc gugaccagca agaaggugau cauccccacc      660

uaccugagaa gcaucagcgu gagaaacaag gaccugaaca cccuggagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacagcgg ccugcugcug      780

gugaucaccg ugaccgacaa caagggcgcc uucaaguaca ucaagcccca gagccaguuc      840

aucguggacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccaccagauu cgccaucaag cccauggagg acugaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9850
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9850
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacgg ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgccucccug accaucuggg ugccuauguu ccaaucuagc      300

augccggcgg aucuucugau uaaggaacuc gcuaacguga auauccuggu caaacagauu      360

uccacaccca aggggccuuc ucuuagagug augaucaaca gccgguccgc cguucuggcc      420

cagaugcccu cuaaauuuac cauuugcgcu aaugugagcc ucgacgagcg cuccaagcug      480

gccuaugaug ucacaacccc uugugaaauc aaggcuugca gccugacaug ucucaaaucu      540

aagaacaugc ugaccacggu gaaagaccuu accaugaaga cacugaaucc cacccaugau      600

aucauugccc ucugcgaguu cgagaacauc guuacaucca aaaaggugau uaucccuacc      660

uaccugagaa gcauuucugu ccggaauaag gaccuuaaca cgcuggaaaa uaucacaacc      720

acagaguuua aaaacgcgau uaccaaugcc aagaucaucc cguauuccgg acuccugcug      780

gugauuaccg ugacagauaa caaaggcgcu uucaaguaca ucaaacccca gagccaauuu      840

auugucgacc ucggggccua ucuggaaaag gagucuaucu acuacguuac gaccaauugg      900

aaacacacag cuacccgcuu cgccauuaag ccuauggagg auugaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9851
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9851
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguaa acaaacuaca cgaaggaucc acauacacag cagcaguaca auacaacgua      240

cuagaaaaag acgacgaccc agcaucuuua accauauggg uaccaauguu ccaaucauca      300

augccagcag accucuuaau aaaagaacua gcaaacguaa acauccuagu caaacaaaua      360

ucaacaccca aaggaccauc ccucagagua augaucaacu caagaucagc aguacuagca      420

caaaugccau caaaauucac aauaugcgcc aacguuucuu uagacgaacg aucaaaauua      480

gccuacgacg uaacaacacc cugcgaaaua aaagcaugcu cacuaacaug ccuaaaauca      540

aaaaacaugc ucacuacagu aaaagaccua accaugaaaa cacucaaccc aacacacgac      600

auaauagccc uaugcgaauu ugaaaacaua guaacaucaa aaaaaguaau aaucccaaca      660

uacuuaagau cgaucucagu cagaaacaaa gaccuaaaua cacucgaaaa cauaacaaca      720

acagaauuua aaaacgcaau aacaaacgca aaaauaauac cauacucagg acuacuccua      780

guaauaacag uaacagacaa caaaggagca uucaaauaca uaaaaccaca aucacaauuc      840

aucguagacc ucggagcaua ccuagaaaaa gaaucaauau acuacguaac aacaaacugg      900

aaacacaccg ccacaagauu cgcaauaaaa cccauggaag acuaaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9852
<211>  1220
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9852
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

accuacguca acaaacuaca cgaaggcuca accuacaccg ccgccgucca auacaacguc      240

cucgaaaaag acgacgaccc cgccucccua accaucuggg uucccauguu ccaaucaucc      300

augcccgccg accuccucau aaaagaacua gccaacguca acauccuagu caaacaaauc      360

agcaccccca aaggccccuc ccuccgcgua augaucaacu cccgcuccgc cguccuagcc      420

caaaugcccu ccaaauuuac aaucugcgcc aacgucuccc ucgacgaacg cucaaaacuc      480

gccuacgacg ucaccacacc cugcgaaauc aaagccugcu cccucaccug ccucaaaagc      540

aaaaauaugc uaaccaccgu caaagaccuu accaugaaaa cccucaaccc cacucacgac      600

aucauagccc ucugcgaauu ugaaaacauc gucaccucca aaaaagucau cauccccaca      660

uaccuccgcu ccaucuccgu ccgcaacaaa gaccucaaca cccucgaaaa caucaccacc      720

accgaauuua aaaacgccau caccaacgcc aaaaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg uuaccgacaa caaaggcgcc uucaaauaca ucaaacccca aucccaauuc      840

aucgucgacc ucggagccua ccuugaaaaa gaguccaucu acuacgucac caccaacugg      900

aaacacaccg ccacccgauu cgccaucaaa cccauggaag acuaaggacu aguggaagca      960

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1020

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1080

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1200

uuuucagagc caccagaauu                                                 1220


<210>  9853
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9853
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaaacauacg ugaacaagcu ucacgaaggc uccacauaca cagcugcugu ucaauacaau      180

gucuuagaaa aagacgauga cccugcauca cuuacaauau gggugcccau guuccaauca      240

ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug ucaacauacu agugaaacaa      300

auauccacac ccaagggacc uucacuaaga gucaugauaa acucaagaag ugcagugcua      360

gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu ccuuggauga aagaagcaaa      420

cuagcauaug auguaaccac acccugugaa aucaaggcau guagucuaac augccuaaaa      480

ucaaaaaaua uguugacuac aguuaaagau cucacuauga agacacucaa cccuacacau      540

gauauuauug cuuuauguga auuugaaaac auaguaacau caaaaaaagu cauaauacca      600

acauaccuaa gauccaucag ugucagaaau aaagaucuga acacacuuga aaauauaaca      660

accacugaau ucaaaaaugc uaucacaaau gcaaaaauca ucccuuacuc aggauuacua      720

uuagucauca cagugacuga caacaaagga gcauucaaau acauaaagcc acaaagucaa      780

uucauaguag aucuuggagc uuaccuagaa aaagaaagua uauauuaugu uaccacaaau      840

uggaagcaca cagcuacacg auuugcaauc aaacccaugg aagauuaagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9854
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9854
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca cggccgccgu ccaguacaac      180

gugcucgaga aggacgacga ccccgcgucc cugaccaucu gggugccgau guuccagagc      240

uccaugcccg ccgaccugcu caucaaggag cuggccaacg ucaacauccu ggugaagcag      300

aucagcaccc ccaaggggcc cucccuccgc gugaugauca acagccgguc cgccguccug      360

gcccagaugc cgagcaaguu caccaucugc gcgaacgugu cccuggacga gcgcagcaag      420

cucgccuacg acgugacgac ccccugcgag aucaaggccu gcucccugac cugccucaag      480

agcaagaaca ugcugaccac ggucaaggac cugaccauga agacccugaa ccccacccac      540

gacaucaucg cccucugcga guucgagaac aucgugacgu ccaagaaggu gaucaucccc      600

accuaccugc ggagcaucuc cguccgcaac aaggaccuga acacccucga gaacaucacc      660

acgaccgagu ucaagaacgc gaucaccaac gccaagauca ucccguacag cggccugcug      720

cucgugauca ccgugacgga caacaagggg gccuucaagu acaucaagcc ccagucccag      780

uucaucgucg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      840

uggaagcaca ccgccacgcg guucgcgauc aagcccaugg aggacugagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9855
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9855
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaccuacg ucaacaagcu ccacgagggc uccaccuaca ccgccgccgu ccaguacaac      180

guccucgaga aggacgacga ccccgccucc cucaccaucu ggguccccau guuccagucc      240

uccaugcccg ccgaccuccu caucaaggag cucgccaacg ucaacauccu cgucaagcag      300

aucuccaccc ccaagggccc cucccuccgc gucaugauca acucccgcuc cgccguccuc      360

gcccagaugc ccuccaaguu caccaucugc gccaacgucu cccucgacga gcgcuccaag      420

cucgccuacg acgucaccac ccccugcgag aucaaggccu gcucccucac cugccucaag      480

uccaagaaca ugcucaccac cgucaaggac cucaccauga agacccucaa ccccacccac      540

gacaucaucg cccucugcga guucgagaac aucgucaccu ccaagaaggu caucaucccc      600

accuaccucc gcuccaucuc cguccgcaac aaggaccuca acacccucga gaacaucacc      660

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacuc cggccuccuc      720

cucgucauca ccgucaccga caacaagggc gccuucaagu acaucaagcc ccagucccag      780

uucaucgucg accucggcgc cuaccucgag aaggagucca ucuacuacgu caccaccaac      840

uggaagcaca ccgccacccg cuucgccauc aagcccaugg aggacugagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9856
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9856
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cugccgcugu ccaguacaau      180

guucucgaga aagacgauga ccccgcaucc cuuacgaucu gggugccuau guuccaaucu      240

ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg uaaauauacu ggugaaacag      300

aucaguaccc cgaaggggcc cagccuaaga gucaugauua acuccagguc ugcugugcuc      360

gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu cacuggacga gcggagcaaa      420

cuugccuaug augugacuac cccaugugaa auuaaggcuu gcagucugac auguuugaag      480

uccaagaaca ugcucaccac ugucaaagac cugacaauga agacccugaa ucccacgcau      540

gauaucauag cacucugcga guucgagaac aucgugacuu cuaaaaaggu aauuaucccu      600

accuacuuac gcagcauuuc cguucgaaau aaggaccuga acacacuuga aaauaucacu      660

accacagagu uuaaaaacgc cauaaccaau gcuaagauua ucccauauuc aggauugcug      720

cuagugauua cggucacuga uaacaaaggu gccuucaagu acaucaaacc ccagagucaa      780

uuuaucgugg accucggcgc guaucuggaa aaggagagca uuuacuacgu gacaaccaau      840

uggaaacaca cugcaacacg uuucgccaua aagccuaugg aggauugagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9857
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9857
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca ccgccgccgu gcaguacaac      180

gugcuggaga aggacgacga ccccgccagc cugaccaucu gggugcccau guuccagagc      240

agcaugcccg ccgaccugcu gaucaaggag cuggccaacg ugaacauccu ggugaagcag      300

aucagcaccc ccaagggccc cagccugaga gugaugauca acagcagaag cgccgugcug      360

gcccagaugc ccagcaaguu caccaucugc gccaacguga gccuggacga gagaagcaag      420

cuggccuacg acgugaccac ccccugcgag aucaaggccu gcagccugac cugccugaag      480

agcaagaaca ugcugaccac cgugaaggac cugaccauga agacccugaa ccccacccac      540

gacaucaucg cccugugcga guucgagaac aucgugacca gcaagaaggu gaucaucccc      600

accuaccuga gaagcaucag cgugagaaac aaggaccuga acacccugga gaacaucacc      660

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacag cggccugcug      720

cuggugauca ccgugaccga caacaagggc gccuucaagu acaucaagcc ccagagccag      780

uucaucgugg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      840

uggaagcaca ccgccaccag auucgccauc aagcccaugg aggacugagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9858
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9858
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cggccgcugu ccaguacaau      180

guucucgaga aagacgauga ccccgccucc cugaccaucu gggugccuau guuccaaucu      240

agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg ugaauauccu ggucaaacag      300

auuuccacac ccaaggggcc uucucuuaga gugaugauca acagccgguc cgccguucug      360

gcccagaugc ccucuaaauu uaccauuugc gcuaauguga gccucgacga gcgcuccaag      420

cuggccuaug augucacaac cccuugugaa aucaaggcuu gcagccugac augucucaaa      480

ucuaagaaca ugcugaccac ggugaaagac cuuaccauga agacacugaa ucccacccau      540

gauaucauug cccucugcga guucgagaac aucguuacau ccaaaaaggu gauuaucccu      600

accuaccuga gaagcauuuc uguccggaau aaggaccuua acacgcugga aaauaucaca      660

accacagagu uuaaaaacgc gauuaccaau gccaagauca ucccguauuc cggacuccug      720

cuggugauua ccgugacaga uaacaaaggc gcuuucaagu acaucaaacc ccagagccaa      780

uuuauugucg accucggggc cuaucuggaa aaggagucua ucuacuacgu uacgaccaau      840

uggaaacaca cagcuacccg cuucgccauu aagccuaugg aggauugagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9859
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9859
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaaacauacg uaaacaaacu acacgaagga uccacauaca cagcagcagu acaauacaac      180

guacuagaaa aagacgacga cccagcaucu uuaaccauau ggguaccaau guuccaauca      240

ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg uaaacauccu agucaaacaa      300

auaucaacac ccaaaggacc aucccucaga guaaugauca acucaagauc agcaguacua      360

gcacaaaugc caucaaaauu cacaauaugc gccaacguuu cuuuagacga acgaucaaaa      420

uuagccuacg acguaacaac acccugcgaa auaaaagcau gcucacuaac augccuaaaa      480

ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga aaacacucaa cccaacacac      540

gacauaauag cccuaugcga auuugaaaac auaguaacau caaaaaaagu aauaauccca      600

acauacuuaa gaucgaucuc agucagaaac aaagaccuaa auacacucga aaacauaaca      660

acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa uaccauacuc aggacuacuc      720

cuaguaauaa caguaacaga caacaaagga gcauucaaau acauaaaacc acaaucacaa      780

uucaucguag accucggagc auaccuagaa aaagaaucaa uauacuacgu aacaacaaac      840

uggaaacaca ccgccacaag auucgcaaua aaacccaugg aagacuaagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9860
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9860
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca ccgccgccgu ccaauacaac      180

guccucgaaa aagacgacga ccccgccucc cuaaccaucu ggguucccau guuccaauca      240

uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg ucaacauccu agucaaacaa      300

aucagcaccc ccaaaggccc cucccuccgc guaaugauca acucccgcuc cgccguccua      360

gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu cccucgacga acgcucaaaa      420

cucgccuacg acgucaccac acccugcgaa aucaaagccu gcucccucac cugccucaaa      480

agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga aaacccucaa ccccacucac      540

gacaucauag cccucugcga auuugaaaac aucgucaccu ccaaaaaagu caucaucccc      600

acauaccucc gcuccaucuc cguccgcaac aaagaccuca acacccucga aaacaucacc      660

accaccgaau uuaaaaacgc caucaccaac gccaaaauca uccccuacuc cggccuccuc      720

cucgucauca ccguuaccga caacaaaggc gccuucaaau acaucaaacc ccaaucccaa      780

uucaucgucg accucggagc cuaccuugaa aaagagucca ucuacuacgu caccaccaac      840

uggaaacaca ccgccacccg auucgccauc aaacccaugg aagacuaagg acuagugucc      900

accugucccu ccugggcugc uggauugucu cguuuuccug ccaaauaaac aggaucagcg      960

cuuuacagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  9861
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9861
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cgugaacaag      120

cuucacgaag gcuccacaua cacagcugcu guucaauaca augucuuaga aaaagacgau      180

gacccugcau cacuuacaau augggugccc auguuccaau caucuaugcc agcagauuua      240

cuuauaaaag aacuagcuaa ugucaacaua cuagugaaac aaauauccac acccaaggga      300

ccuucacuaa gagucaugau aaacucaaga agugcagugc uagcacaaau gcccagcaaa      360

uuuaccauau gcgcuaaugu guccuuggau gaaagaagca aacuagcaua ugauguaacc      420

acacccugug aaaucaaggc auguagucua acaugccuaa aaucaaaaaa uauguugacu      480

acaguuaaag aucucacuau gaagacacuc aacccuacac augauauuau ugcuuuaugu      540

gaauuugaaa acauaguaac aucaaaaaaa gucauaauac caacauaccu aagauccauc      600

agugucagaa auaaagaucu gaacacacuu gaaaauauaa caaccacuga auucaaaaau      660

gcuaucacaa augcaaaaau caucccuuac ucaggauuac uauuagucau cacagugacu      720

gacaacaaag gagcauucaa auacauaaag ccacaaaguc aauucauagu agaucuugga      780

gcuuaccuag aaaaagaaag uauauauuau guuaccacaa auuggaagca cacagcuaca      840

cgauuugcaa ucaaacccau ggaagauuaa ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9862
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9862
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua cacggccgcc guccaguaca acgugcucga gaaggacgac      180

gaccccgcgu cccugaccau cugggugccg auguuccaga gcuccaugcc cgccgaccug      240

cucaucaagg agcuggccaa cgucaacauc cuggugaagc agaucagcac ccccaagggg      300

cccucccucc gcgugaugau caacagccgg uccgccgucc uggcccagau gccgagcaag      360

uucaccaucu gcgcgaacgu gucccuggac gagcgcagca agcucgccua cgacgugacg      420

acccccugcg agaucaaggc cugcucccug accugccuca agagcaagaa caugcugacc      480

acggucaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgugac guccaagaag gugaucaucc ccaccuaccu gcggagcauc      600

uccguccgca acaaggaccu gaacacccuc gagaacauca ccacgaccga guucaagaac      660

gcgaucacca acgccaagau caucccguac agcggccugc ugcucgugau caccgugacg      720

gacaacaagg gggccuucaa guacaucaag ccccaguccc aguucaucgu cgaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacg      840

cgguucgcga ucaagcccau ggaggacuga ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9863
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9863
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgucaacaag      120

cuccacgagg gcuccaccua caccgccgcc guccaguaca acguccucga gaaggacgac      180

gaccccgccu cccucaccau cugggucccc auguuccagu ccuccaugcc cgccgaccuc      240

cucaucaagg agcucgccaa cgucaacauc cucgucaagc agaucuccac ccccaagggc      300

cccucccucc gcgucaugau caacucccgc uccgccgucc ucgcccagau gcccuccaag      360

uucaccaucu gcgccaacgu cucccucgac gagcgcucca agcucgccua cgacgucacc      420

acccccugcg agaucaaggc cugcucccuc accugccuca aguccaagaa caugcucacc      480

accgucaagg accucaccau gaagacccuc aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgucac cuccaagaag gucaucaucc ccaccuaccu ccgcuccauc      600

uccguccgca acaaggaccu caacacccuc gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac uccggccucc uccucgucau caccgucacc      720

gacaacaagg gcgccuucaa guacaucaag ccccaguccc aguucaucgu cgaccucggc      780

gccuaccucg agaaggaguc caucuacuac gucaccacca acuggaagca caccgccacc      840

cgcuucgcca ucaagcccau ggaggacuga ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9864
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9864
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacugccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgcau cccuuacgau cugggugccu auguuccaau cuucaaugcc agccgaucug      240

uugauuaagg aauuagcgaa cguaaauaua cuggugaaac agaucaguac cccgaagggg      300

cccagccuaa gagucaugau uaacuccagg ucugcugugc ucgcccagau gccuucgaaa      360

uuuacaaucu gcgcaaaugu uucacuggac gagcggagca aacuugccua ugaugugacu      420

accccaugug aaauuaaggc uugcagucug acauguuuga aguccaagaa caugcucacc      480

acugucaaag accugacaau gaagacccug aaucccacgc augauaucau agcacucugc      540

gaguucgaga acaucgugac uucuaaaaag guaauuaucc cuaccuacuu acgcagcauu      600

uccguucgaa auaaggaccu gaacacacuu gaaaauauca cuaccacaga guuuaaaaac      660

gccauaacca augcuaagau uaucccauau ucaggauugc ugcuagugau uacggucacu      720

gauaacaaag gugccuucaa guacaucaaa ccccagaguc aauuuaucgu ggaccucggc      780

gcguaucugg aaaaggagag cauuuacuac gugacaacca auuggaaaca cacugcaaca      840

cguuucgcca uaaagccuau ggaggauuga ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9865
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9865
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua caccgccgcc gugcaguaca acgugcugga gaaggacgac      180

gaccccgcca gccugaccau cugggugccc auguuccaga gcagcaugcc cgccgaccug      240

cugaucaagg agcuggccaa cgugaacauc cuggugaagc agaucagcac ccccaagggc      300

cccagccuga gagugaugau caacagcaga agcgccgugc uggcccagau gcccagcaag      360

uucaccaucu gcgccaacgu gagccuggac gagagaagca agcuggccua cgacgugacc      420

acccccugcg agaucaaggc cugcagccug accugccuga agagcaagaa caugcugacc      480

accgugaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccugugc      540

gaguucgaga acaucgugac cagcaagaag gugaucaucc ccaccuaccu gagaagcauc      600

agcgugagaa acaaggaccu gaacacccug gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac agcggccugc ugcuggugau caccgugacc      720

gacaacaagg gcgccuucaa guacaucaag ccccagagcc aguucaucgu ggaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacc      840

agauucgcca ucaagcccau ggaggacuga ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9866
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9866
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacggccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgccu cccugaccau cugggugccu auguuccaau cuagcaugcc ggcggaucuu      240

cugauuaagg aacucgcuaa cgugaauauc cuggucaaac agauuuccac acccaagggg      300

ccuucucuua gagugaugau caacagccgg uccgccguuc uggcccagau gcccucuaaa      360

uuuaccauuu gcgcuaaugu gagccucgac gagcgcucca agcuggccua ugaugucaca      420

accccuugug aaaucaaggc uugcagccug acaugucuca aaucuaagaa caugcugacc      480

acggugaaag accuuaccau gaagacacug aaucccaccc augauaucau ugcccucugc      540

gaguucgaga acaucguuac auccaaaaag gugauuaucc cuaccuaccu gagaagcauu      600

ucuguccgga auaaggaccu uaacacgcug gaaaauauca caaccacaga guuuaaaaac      660

gcgauuacca augccaagau caucccguau uccggacucc ugcuggugau uaccgugaca      720

gauaacaaag gcgcuuucaa guacaucaaa ccccagagcc aauuuauugu cgaccucggg      780

gccuaucugg aaaaggaguc uaucuacuac guuacgacca auuggaaaca cacagcuacc      840

cgcuucgcca uuaagccuau ggaggauuga ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9867
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9867
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cguaaacaaa      120

cuacacgaag gauccacaua cacagcagca guacaauaca acguacuaga aaaagacgac      180

gacccagcau cuuuaaccau auggguacca auguuccaau caucaaugcc agcagaccuc      240

uuaauaaaag aacuagcaaa cguaaacauc cuagucaaac aaauaucaac acccaaagga      300

ccaucccuca gaguaaugau caacucaaga ucagcaguac uagcacaaau gccaucaaaa      360

uucacaauau gcgccaacgu uucuuuagac gaacgaucaa aauuagccua cgacguaaca      420

acacccugcg aaauaaaagc augcucacua acaugccuaa aaucaaaaaa caugcucacu      480

acaguaaaag accuaaccau gaaaacacuc aacccaacac acgacauaau agcccuaugc      540

gaauuugaaa acauaguaac aucaaaaaaa guaauaaucc caacauacuu aagaucgauc      600

ucagucagaa acaaagaccu aaauacacuc gaaaacauaa caacaacaga auuuaaaaac      660

gcaauaacaa acgcaaaaau aauaccauac ucaggacuac uccuaguaau aacaguaaca      720

gacaacaaag gagcauucaa auacauaaaa ccacaaucac aauucaucgu agaccucgga      780

gcauaccuag aaaaagaauc aauauacuac guaacaacaa acuggaaaca caccgccaca      840

agauucgcaa uaaaacccau ggaagacuaa ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9868
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9868
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaccua cgucaacaaa      120

cuacacgaag gcucaaccua caccgccgcc guccaauaca acguccucga aaaagacgac      180

gaccccgccu cccuaaccau cuggguuccc auguuccaau cauccaugcc cgccgaccuc      240

cucauaaaag aacuagccaa cgucaacauc cuagucaaac aaaucagcac ccccaaaggc      300

cccucccucc gcguaaugau caacucccgc uccgccgucc uagcccaaau gcccuccaaa      360

uuuacaaucu gcgccaacgu cucccucgac gaacgcucaa aacucgccua cgacgucacc      420

acacccugcg aaaucaaagc cugcucccuc accugccuca aaagcaaaaa uaugcuaacc      480

accgucaaag accuuaccau gaaaacccuc aaccccacuc acgacaucau agcccucugc      540

gaauuugaaa acaucgucac cuccaaaaaa gucaucaucc ccacauaccu ccgcuccauc      600

uccguccgca acaaagaccu caacacccuc gaaaacauca ccaccaccga auuuaaaaac      660

gccaucacca acgccaaaau cauccccuac uccggccucc uccucgucau caccguuacc      720

gacaacaaag gcgccuucaa auacaucaaa ccccaauccc aauucaucgu cgaccucgga      780

gccuaccuug aaaaagaguc caucuacuac gucaccacca acuggaaaca caccgccacc      840

cgauucgcca ucaaacccau ggaagacuaa ggacuagugu ccaccugucc cuccugggcu      900

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  9869
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9869
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cgugaacaag cuucacgaag gcuccacaua cacagcugcu      120

guucaauaca augucuuaga aaaagacgau gacccugcau cacuuacaau augggugccc      180

auguuccaau caucuaugcc agcagauuua cuuauaaaag aacuagcuaa ugucaacaua      240

cuagugaaac aaauauccac acccaaggga ccuucacuaa gagucaugau aaacucaaga      300

agugcagugc uagcacaaau gcccagcaaa uuuaccauau gcgcuaaugu guccuuggau      360

gaaagaagca aacuagcaua ugauguaacc acacccugug aaaucaaggc auguagucua      420

acaugccuaa aaucaaaaaa uauguugacu acaguuaaag aucucacuau gaagacacuc      480

aacccuacac augauauuau ugcuuuaugu gaauuugaaa acauaguaac aucaaaaaaa      540

gucauaauac caacauaccu aagauccauc agugucagaa auaaagaucu gaacacacuu      600

gaaaauauaa caaccacuga auucaaaaau gcuaucacaa augcaaaaau caucccuuac      660

ucaggauuac uauuagucau cacagugacu gacaacaaag gagcauucaa auacauaaag      720

ccacaaaguc aauucauagu agaucuugga gcuuaccuag aaaaagaaag uauauauuau      780

guuaccacaa auuggaagca cacagcuaca cgauuugcaa ucaaacccau ggaagauuaa      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9870
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9870
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua cacggccgcc      120

guccaguaca acgugcucga gaaggacgac gaccccgcgu cccugaccau cugggugccg      180

auguuccaga gcuccaugcc cgccgaccug cucaucaagg agcuggccaa cgucaacauc      240

cuggugaagc agaucagcac ccccaagggg cccucccucc gcgugaugau caacagccgg      300

uccgccgucc uggcccagau gccgagcaag uucaccaucu gcgcgaacgu gucccuggac      360

gagcgcagca agcucgccua cgacgugacg acccccugcg agaucaaggc cugcucccug      420

accugccuca agagcaagaa caugcugacc acggucaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgugac guccaagaag      540

gugaucaucc ccaccuaccu gcggagcauc uccguccgca acaaggaccu gaacacccuc      600

gagaacauca ccacgaccga guucaagaac gcgaucacca acgccaagau caucccguac      660

agcggccugc ugcucgugau caccgugacg gacaacaagg gggccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacg cgguucgcga ucaagcccau ggaggacuga      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9871
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9871
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgucaacaag cuccacgagg gcuccaccua caccgccgcc      120

guccaguaca acguccucga gaaggacgac gaccccgccu cccucaccau cugggucccc      180

auguuccagu ccuccaugcc cgccgaccuc cucaucaagg agcucgccaa cgucaacauc      240

cucgucaagc agaucuccac ccccaagggc cccucccucc gcgucaugau caacucccgc      300

uccgccgucc ucgcccagau gcccuccaag uucaccaucu gcgccaacgu cucccucgac      360

gagcgcucca agcucgccua cgacgucacc acccccugcg agaucaaggc cugcucccuc      420

accugccuca aguccaagaa caugcucacc accgucaagg accucaccau gaagacccuc      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgucac cuccaagaag      540

gucaucaucc ccaccuaccu ccgcuccauc uccguccgca acaaggaccu caacacccuc      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

uccggccucc uccucgucau caccgucacc gacaacaagg gcgccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccucggc gccuaccucg agaaggaguc caucuacuac      780

gucaccacca acuggaagca caccgccacc cgcuucgcca ucaagcccau ggaggacuga      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9872
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9872
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacugccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgcau cccuuacgau cugggugccu      180

auguuccaau cuucaaugcc agccgaucug uugauuaagg aauuagcgaa cguaaauaua      240

cuggugaaac agaucaguac cccgaagggg cccagccuaa gagucaugau uaacuccagg      300

ucugcugugc ucgcccagau gccuucgaaa uuuacaaucu gcgcaaaugu uucacuggac      360

gagcggagca aacuugccua ugaugugacu accccaugug aaauuaaggc uugcagucug      420

acauguuuga aguccaagaa caugcucacc acugucaaag accugacaau gaagacccug      480

aaucccacgc augauaucau agcacucugc gaguucgaga acaucgugac uucuaaaaag      540

guaauuaucc cuaccuacuu acgcagcauu uccguucgaa auaaggaccu gaacacacuu      600

gaaaauauca cuaccacaga guuuaaaaac gccauaacca augcuaagau uaucccauau      660

ucaggauugc ugcuagugau uacggucacu gauaacaaag gugccuucaa guacaucaaa      720

ccccagaguc aauuuaucgu ggaccucggc gcguaucugg aaaaggagag cauuuacuac      780

gugacaacca auuggaaaca cacugcaaca cguuucgcca uaaagccuau ggaggauuga      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9873
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9873
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua caccgccgcc      120

gugcaguaca acgugcugga gaaggacgac gaccccgcca gccugaccau cugggugccc      180

auguuccaga gcagcaugcc cgccgaccug cugaucaagg agcuggccaa cgugaacauc      240

cuggugaagc agaucagcac ccccaagggc cccagccuga gagugaugau caacagcaga      300

agcgccgugc uggcccagau gcccagcaag uucaccaucu gcgccaacgu gagccuggac      360

gagagaagca agcuggccua cgacgugacc acccccugcg agaucaaggc cugcagccug      420

accugccuga agagcaagaa caugcugacc accgugaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccugugc gaguucgaga acaucgugac cagcaagaag      540

gugaucaucc ccaccuaccu gagaagcauc agcgugagaa acaaggaccu gaacacccug      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

agcggccugc ugcuggugau caccgugacc gacaacaagg gcgccuucaa guacaucaag      720

ccccagagcc aguucaucgu ggaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacc agauucgcca ucaagcccau ggaggacuga      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9874
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9874
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacggccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgccu cccugaccau cugggugccu      180

auguuccaau cuagcaugcc ggcggaucuu cugauuaagg aacucgcuaa cgugaauauc      240

cuggucaaac agauuuccac acccaagggg ccuucucuua gagugaugau caacagccgg      300

uccgccguuc uggcccagau gcccucuaaa uuuaccauuu gcgcuaaugu gagccucgac      360

gagcgcucca agcuggccua ugaugucaca accccuugug aaaucaaggc uugcagccug      420

acaugucuca aaucuaagaa caugcugacc acggugaaag accuuaccau gaagacacug      480

aaucccaccc augauaucau ugcccucugc gaguucgaga acaucguuac auccaaaaag      540

gugauuaucc cuaccuaccu gagaagcauu ucuguccgga auaaggaccu uaacacgcug      600

gaaaauauca caaccacaga guuuaaaaac gcgauuacca augccaagau caucccguau      660

uccggacucc ugcuggugau uaccgugaca gauaacaaag gcgcuuucaa guacaucaaa      720

ccccagagcc aauuuauugu cgaccucggg gccuaucugg aaaaggaguc uaucuacuac      780

guuacgacca auuggaaaca cacagcuacc cgcuucgcca uuaagccuau ggaggauuga      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9875
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9875
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cguaaacaaa cuacacgaag gauccacaua cacagcagca      120

guacaauaca acguacuaga aaaagacgac gacccagcau cuuuaaccau auggguacca      180

auguuccaau caucaaugcc agcagaccuc uuaauaaaag aacuagcaaa cguaaacauc      240

cuagucaaac aaauaucaac acccaaagga ccaucccuca gaguaaugau caacucaaga      300

ucagcaguac uagcacaaau gccaucaaaa uucacaauau gcgccaacgu uucuuuagac      360

gaacgaucaa aauuagccua cgacguaaca acacccugcg aaauaaaagc augcucacua      420

acaugccuaa aaucaaaaaa caugcucacu acaguaaaag accuaaccau gaaaacacuc      480

aacccaacac acgacauaau agcccuaugc gaauuugaaa acauaguaac aucaaaaaaa      540

guaauaaucc caacauacuu aagaucgauc ucagucagaa acaaagaccu aaauacacuc      600

gaaaacauaa caacaacaga auuuaaaaac gcaauaacaa acgcaaaaau aauaccauac      660

ucaggacuac uccuaguaau aacaguaaca gacaacaaag gagcauucaa auacauaaaa      720

ccacaaucac aauucaucgu agaccucgga gcauaccuag aaaaagaauc aauauacuac      780

guaacaacaa acuggaaaca caccgccaca agauucgcaa uaaaacccau ggaagacuaa      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9876
<211>  1052
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9876
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaccua cgucaacaaa cuacacgaag gcucaaccua caccgccgcc      120

guccaauaca acguccucga aaaagacgac gaccccgccu cccuaaccau cuggguuccc      180

auguuccaau cauccaugcc cgccgaccuc cucauaaaag aacuagccaa cgucaacauc      240

cuagucaaac aaaucagcac ccccaaaggc cccucccucc gcguaaugau caacucccgc      300

uccgccgucc uagcccaaau gcccuccaaa uuuacaaucu gcgccaacgu cucccucgac      360

gaacgcucaa aacucgccua cgacgucacc acacccugcg aaaucaaagc cugcucccuc      420

accugccuca aaagcaaaaa uaugcuaacc accgucaaag accuuaccau gaaaacccuc      480

aaccccacuc acgacaucau agcccucugc gaauuugaaa acaucgucac cuccaaaaaa      540

gucaucaucc ccacauaccu ccgcuccauc uccguccgca acaaagaccu caacacccuc      600

gaaaacauca ccaccaccga auuuaaaaac gccaucacca acgccaaaau cauccccuac      660

uccggccucc uccucgucau caccguuacc gacaacaaag gcgccuucaa auacaucaaa      720

ccccaauccc aauucaucgu cgaccucgga gccuaccuug aaaaagaguc caucuacuac      780

gucaccacca acuggaaaca caccgccacc cgauucgcca ucaaacccau ggaagacuaa      840

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      900

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1020

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1052


<210>  9877
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9877
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacgugaa caagcuucac gaaggcucca cauacacagc ugcuguucaa      180

uacaaugucu uagaaaaaga cgaugacccu gcaucacuua caauaugggu gcccauguuc      240

caaucaucua ugccagcaga uuuacuuaua aaagaacuag cuaaugucaa cauacuagug      300

aaacaaauau ccacacccaa gggaccuuca cuaagaguca ugauaaacuc aagaagugca      360

gugcuagcac aaaugcccag caaauuuacc auaugcgcua auguguccuu ggaugaaaga      420

agcaaacuag cauaugaugu aaccacaccc ugugaaauca aggcauguag ucuaacaugc      480

cuaaaaucaa aaaauauguu gacuacaguu aaagaucuca cuaugaagac acucaacccu      540

acacaugaua uuauugcuuu augugaauuu gaaaacauag uaacaucaaa aaaagucaua      600

auaccaacau accuaagauc caucaguguc agaaauaaag aucugaacac acuugaaaau      660

auaacaacca cugaauucaa aaaugcuauc acaaaugcaa aaaucauccc uuacucagga      720

uuacuauuag ucaucacagu gacugacaac aaaggagcau ucaaauacau aaagccacaa      780

agucaauuca uaguagaucu uggagcuuac cuagaaaaag aaaguauaua uuauguuacc      840

acaaauugga agcacacagc uacacgauuu gcaaucaaac ccauggaaga uuaaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9878
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9878
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacacggc cgccguccag      180

uacaacgugc ucgagaagga cgacgacccc gcgucccuga ccaucugggu gccgauguuc      240

cagagcucca ugcccgccga ccugcucauc aaggagcugg ccaacgucaa cauccuggug      300

aagcagauca gcacccccaa ggggcccucc cuccgcguga ugaucaacag ccgguccgcc      360

guccuggccc agaugccgag caaguucacc aucugcgcga acgugucccu ggacgagcgc      420

agcaagcucg ccuacgacgu gacgaccccc ugcgagauca aggccugcuc ccugaccugc      480

cucaagagca agaacaugcu gaccacgguc aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ugacguccaa gaaggugauc      600

auccccaccu accugcggag caucuccguc cgcaacaagg accugaacac ccucgagaac      660

aucaccacga ccgaguucaa gaacgcgauc accaacgcca agaucauccc guacagcggc      720

cugcugcucg ugaucaccgu gacggacaac aagggggccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc cacgcgguuc gcgaucaagc ccauggagga cugaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9879
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9879
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgucaa caagcuccac gagggcucca ccuacaccgc cgccguccag      180

uacaacgucc ucgagaagga cgacgacccc gccucccuca ccaucugggu ccccauguuc      240

caguccucca ugcccgccga ccuccucauc aaggagcucg ccaacgucaa cauccucguc      300

aagcagaucu ccacccccaa gggccccucc cuccgcguca ugaucaacuc ccgcuccgcc      360

guccucgccc agaugcccuc caaguucacc aucugcgcca acgucucccu cgacgagcgc      420

uccaagcucg ccuacgacgu caccaccccc ugcgagauca aggccugcuc ccucaccugc      480

cucaagucca agaacaugcu caccaccguc aaggaccuca ccaugaagac ccucaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ucaccuccaa gaaggucauc      600

auccccaccu accuccgcuc caucuccguc cgcaacaagg accucaacac ccucgagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu caccgacaac aagggcgccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu cggcgccuac cucgagaagg aguccaucua cuacgucacc      840

accaacugga agcacaccgc cacccgcuuc gccaucaagc ccauggagga cugaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9880
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9880
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacugc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gcaucccuua cgaucugggu gccuauguuc      240

caaucuucaa ugccagccga ucuguugauu aaggaauuag cgaacguaaa uauacuggug      300

aaacagauca guaccccgaa ggggcccagc cuaagaguca ugauuaacuc caggucugcu      360

gugcucgccc agaugccuuc gaaauuuaca aucugcgcaa auguuucacu ggacgagcgg      420

agcaaacuug ccuaugaugu gacuacccca ugugaaauua aggcuugcag ucugacaugu      480

uugaagucca agaacaugcu caccacuguc aaagaccuga caaugaagac ccugaauccc      540

acgcaugaua ucauagcacu cugcgaguuc gagaacaucg ugacuucuaa aaagguaauu      600

aucccuaccu acuuacgcag cauuuccguu cgaaauaagg accugaacac acuugaaaau      660

aucacuacca cagaguuuaa aaacgccaua accaaugcua agauuauccc auauucagga      720

uugcugcuag ugauuacggu cacugauaac aaaggugccu ucaaguacau caaaccccag      780

agucaauuua ucguggaccu cggcgcguau cuggaaaagg agagcauuua cuacgugaca      840

accaauugga aacacacugc aacacguuuc gccauaaagc cuauggagga uugaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9881
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9881
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacaccgc cgccgugcag      180

uacaacgugc uggagaagga cgacgacccc gccagccuga ccaucugggu gcccauguuc      240

cagagcagca ugcccgccga ccugcugauc aaggagcugg ccaacgugaa cauccuggug      300

aagcagauca gcacccccaa gggccccagc cugagaguga ugaucaacag cagaagcgcc      360

gugcuggccc agaugcccag caaguucacc aucugcgcca acgugagccu ggacgagaga      420

agcaagcugg ccuacgacgu gaccaccccc ugcgagauca aggccugcag ccugaccugc      480

cugaagagca agaacaugcu gaccaccgug aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu gugcgaguuc gagaacaucg ugaccagcaa gaaggugauc      600

auccccaccu accugagaag caucagcgug agaaacaagg accugaacac ccuggagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacagcggc      720

cugcugcugg ugaucaccgu gaccgacaac aagggcgccu ucaaguacau caagccccag      780

agccaguuca ucguggaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc caccagauuc gccaucaagc ccauggagga cugaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9882
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9882
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacggc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gccucccuga ccaucugggu gccuauguuc      240

caaucuagca ugccggcgga ucuucugauu aaggaacucg cuaacgugaa uauccugguc      300

aaacagauuu ccacacccaa ggggccuucu cuuagaguga ugaucaacag ccgguccgcc      360

guucuggccc agaugcccuc uaaauuuacc auuugcgcua augugagccu cgacgagcgc      420

uccaagcugg ccuaugaugu cacaaccccu ugugaaauca aggcuugcag ccugacaugu      480

cucaaaucua agaacaugcu gaccacggug aaagaccuua ccaugaagac acugaauccc      540

acccaugaua ucauugcccu cugcgaguuc gagaacaucg uuacauccaa aaaggugauu      600

aucccuaccu accugagaag cauuucuguc cggaauaagg accuuaacac gcuggaaaau      660

aucacaacca cagaguuuaa aaacgcgauu accaaugcca agaucauccc guauuccgga      720

cuccugcugg ugauuaccgu gacagauaac aaaggcgcuu ucaaguacau caaaccccag      780

agccaauuua uugucgaccu cggggccuau cuggaaaagg agucuaucua cuacguuacg      840

accaauugga aacacacagc uacccgcuuc gccauuaagc cuauggagga uugaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9883
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9883
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacguaaa caaacuacac gaaggaucca cauacacagc agcaguacaa      180

uacaacguac uagaaaaaga cgacgaccca gcaucuuuaa ccauaugggu accaauguuc      240

caaucaucaa ugccagcaga ccucuuaaua aaagaacuag caaacguaaa cauccuaguc      300

aaacaaauau caacacccaa aggaccaucc cucagaguaa ugaucaacuc aagaucagca      360

guacuagcac aaaugccauc aaaauucaca auaugcgcca acguuucuuu agacgaacga      420

ucaaaauuag ccuacgacgu aacaacaccc ugcgaaauaa aagcaugcuc acuaacaugc      480

cuaaaaucaa aaaacaugcu cacuacagua aaagaccuaa ccaugaaaac acucaaccca      540

acacacgaca uaauagcccu augcgaauuu gaaaacauag uaacaucaaa aaaaguaaua      600

aucccaacau acuuaagauc gaucucaguc agaaacaaag accuaaauac acucgaaaac      660

auaacaacaa cagaauuuaa aaacgcaaua acaaacgcaa aaauaauacc auacucagga      720

cuacuccuag uaauaacagu aacagacaac aaaggagcau ucaaauacau aaaaccacaa      780

ucacaauuca ucguagaccu cggagcauac cuagaaaaag aaucaauaua cuacguaaca      840

acaaacugga aacacaccgc cacaagauuc gcaauaaaac ccauggaaga cuaaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9884
<211>  1106
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9884
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa ccuacgucaa caaacuacac gaaggcucaa ccuacaccgc cgccguccaa      180

uacaacgucc ucgaaaaaga cgacgacccc gccucccuaa ccaucugggu ucccauguuc      240

caaucaucca ugcccgccga ccuccucaua aaagaacuag ccaacgucaa cauccuaguc      300

aaacaaauca gcacccccaa aggccccucc cuccgcguaa ugaucaacuc ccgcuccgcc      360

guccuagccc aaaugcccuc caaauuuaca aucugcgcca acgucucccu cgacgaacgc      420

ucaaaacucg ccuacgacgu caccacaccc ugcgaaauca aagccugcuc ccucaccugc      480

cucaaaagca aaaauaugcu aaccaccguc aaagaccuua ccaugaaaac ccucaacccc      540

acucacgaca ucauagcccu cugcgaauuu gaaaacaucg ucaccuccaa aaaagucauc      600

auccccacau accuccgcuc caucuccguc cgcaacaaag accucaacac ccucgaaaac      660

aucaccacca ccgaauuuaa aaacgccauc accaacgcca aaaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu uaccgacaac aaaggcgccu ucaaauacau caaaccccaa      780

ucccaauuca ucgucgaccu cggagccuac cuugaaaaag aguccaucua cuacgucacc      840

accaacugga aacacaccgc cacccgauuc gccaucaaac ccauggaaga cuaaggacua      900

guguccaccu gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga      960

ucagcgcuuu acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa     1080

aggcucuuuu cagagccacc agaauu                                          1106


<210>  9885
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9885
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acgugaacaa gcuucacgaa      120

ggcuccacau acacagcugc uguucaauac aaugucuuag aaaaagacga ugacccugca      180

ucacuuacaa uaugggugcc cauguuccaa ucaucuaugc cagcagauuu acuuauaaaa      240

gaacuagcua augucaacau acuagugaaa caaauaucca cacccaaggg accuucacua      300

agagucauga uaaacucaag aagugcagug cuagcacaaa ugcccagcaa auuuaccaua      360

ugcgcuaaug uguccuugga ugaaagaagc aaacuagcau augauguaac cacacccugu      420

gaaaucaagg cauguagucu aacaugccua aaaucaaaaa auauguugac uacaguuaaa      480

gaucucacua ugaagacacu caacccuaca caugauauua uugcuuuaug ugaauuugaa      540

aacauaguaa caucaaaaaa agucauaaua ccaacauacc uaagauccau cagugucaga      600

aauaaagauc ugaacacacu ugaaaauaua acaaccacug aauucaaaaa ugcuaucaca      660

aaugcaaaaa ucaucccuua cucaggauua cuauuaguca ucacagugac ugacaacaaa      720

ggagcauuca aauacauaaa gccacaaagu caauucauag uagaucuugg agcuuaccua      780

gaaaaagaaa guauauauua uguuaccaca aauuggaagc acacagcuac acgauuugca      840

aucaaaccca uggaagauua aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9886
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9886
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acacggccgc cguccaguac aacgugcucg agaaggacga cgaccccgcg      180

ucccugacca ucugggugcc gauguuccag agcuccaugc ccgccgaccu gcucaucaag      240

gagcuggcca acgucaacau ccuggugaag cagaucagca cccccaaggg gcccucccuc      300

cgcgugauga ucaacagccg guccgccguc cuggcccaga ugccgagcaa guucaccauc      360

ugcgcgaacg ugucccugga cgagcgcagc aagcucgccu acgacgugac gacccccugc      420

gagaucaagg ccugcucccu gaccugccuc aagagcaaga acaugcugac cacggucaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguga cguccaagaa ggugaucauc cccaccuacc ugcggagcau cuccguccgc      600

aacaaggacc ugaacacccu cgagaacauc accacgaccg aguucaagaa cgcgaucacc      660

aacgccaaga ucaucccgua cagcggccug cugcucguga ucaccgugac ggacaacaag      720

ggggccuuca aguacaucaa gccccagucc caguucaucg ucgaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac gcgguucgcg      840

aucaagccca uggaggacug aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9887
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9887
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgucaacaa gcuccacgag      120

ggcuccaccu acaccgccgc cguccaguac aacguccucg agaaggacga cgaccccgcc      180

ucccucacca ucuggguccc cauguuccag uccuccaugc ccgccgaccu ccucaucaag      240

gagcucgcca acgucaacau ccucgucaag cagaucucca cccccaaggg ccccucccuc      300

cgcgucauga ucaacucccg cuccgccguc cucgcccaga ugcccuccaa guucaccauc      360

ugcgccaacg ucucccucga cgagcgcucc aagcucgccu acgacgucac cacccccugc      420

gagaucaagg ccugcucccu caccugccuc aaguccaaga acaugcucac caccgucaag      480

gaccucacca ugaagacccu caaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguca ccuccaagaa ggucaucauc cccaccuacc uccgcuccau cuccguccgc      600

aacaaggacc ucaacacccu cgagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cuccggccuc cuccucguca ucaccgucac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagucc caguucaucg ucgaccucgg cgccuaccuc      780

gagaaggagu ccaucuacua cgucaccacc aacuggaagc acaccgccac ccgcuucgcc      840

aucaagccca uggaggacug aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9888
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9888
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacugccgc uguccaguac aauguucucg agaaagacga ugaccccgca      180

ucccuuacga ucugggugcc uauguuccaa ucuucaaugc cagccgaucu guugauuaag      240

gaauuagcga acguaaauau acuggugaaa cagaucagua ccccgaaggg gcccagccua      300

agagucauga uuaacuccag gucugcugug cucgcccaga ugccuucgaa auuuacaauc      360

ugcgcaaaug uuucacugga cgagcggagc aaacuugccu augaugugac uaccccaugu      420

gaaauuaagg cuugcagucu gacauguuug aaguccaaga acaugcucac cacugucaaa      480

gaccugacaa ugaagacccu gaaucccacg caugauauca uagcacucug cgaguucgag      540

aacaucguga cuucuaaaaa gguaauuauc ccuaccuacu uacgcagcau uuccguucga      600

aauaaggacc ugaacacacu ugaaaauauc acuaccacag aguuuaaaaa cgccauaacc      660

aaugcuaaga uuaucccaua uucaggauug cugcuaguga uuacggucac ugauaacaaa      720

ggugccuuca aguacaucaa accccagagu caauuuaucg uggaccucgg cgcguaucug      780

gaaaaggaga gcauuuacua cgugacaacc aauuggaaac acacugcaac acguuucgcc      840

auaaagccua uggaggauug aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9889
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9889
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acaccgccgc cgugcaguac aacgugcugg agaaggacga cgaccccgcc      180

agccugacca ucugggugcc cauguuccag agcagcaugc ccgccgaccu gcugaucaag      240

gagcuggcca acgugaacau ccuggugaag cagaucagca cccccaaggg ccccagccug      300

agagugauga ucaacagcag aagcgccgug cuggcccaga ugcccagcaa guucaccauc      360

ugcgccaacg ugagccugga cgagagaagc aagcuggccu acgacgugac cacccccugc      420

gagaucaagg ccugcagccu gaccugccug aagagcaaga acaugcugac caccgugaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccugug cgaguucgag      540

aacaucguga ccagcaagaa ggugaucauc cccaccuacc ugagaagcau cagcgugaga      600

aacaaggacc ugaacacccu ggagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cagcggccug cugcugguga ucaccgugac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagagc caguucaucg uggaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac cagauucgcc      840

aucaagccca uggaggacug aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9890
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9890
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacggccgc uguccaguac aauguucucg agaaagacga ugaccccgcc      180

ucccugacca ucugggugcc uauguuccaa ucuagcaugc cggcggaucu ucugauuaag      240

gaacucgcua acgugaauau ccuggucaaa cagauuucca cacccaaggg gccuucucuu      300

agagugauga ucaacagccg guccgccguu cuggcccaga ugcccucuaa auuuaccauu      360

ugcgcuaaug ugagccucga cgagcgcucc aagcuggccu augaugucac aaccccuugu      420

gaaaucaagg cuugcagccu gacaugucuc aaaucuaaga acaugcugac cacggugaaa      480

gaccuuacca ugaagacacu gaaucccacc caugauauca uugcccucug cgaguucgag      540

aacaucguua cauccaaaaa ggugauuauc ccuaccuacc ugagaagcau uucuguccgg      600

aauaaggacc uuaacacgcu ggaaaauauc acaaccacag aguuuaaaaa cgcgauuacc      660

aaugccaaga ucaucccgua uuccggacuc cugcugguga uuaccgugac agauaacaaa      720

ggcgcuuuca aguacaucaa accccagagc caauuuauug ucgaccucgg ggccuaucug      780

gaaaaggagu cuaucuacua cguuacgacc aauuggaaac acacagcuac ccgcuucgcc      840

auuaagccua uggaggauug aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9891
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9891
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acguaaacaa acuacacgaa      120

ggauccacau acacagcagc aguacaauac aacguacuag aaaaagacga cgacccagca      180

ucuuuaacca uauggguacc aauguuccaa ucaucaaugc cagcagaccu cuuaauaaaa      240

gaacuagcaa acguaaacau ccuagucaaa caaauaucaa cacccaaagg accaucccuc      300

agaguaauga ucaacucaag aucagcagua cuagcacaaa ugccaucaaa auucacaaua      360

ugcgccaacg uuucuuuaga cgaacgauca aaauuagccu acgacguaac aacacccugc      420

gaaauaaaag caugcucacu aacaugccua aaaucaaaaa acaugcucac uacaguaaaa      480

gaccuaacca ugaaaacacu caacccaaca cacgacauaa uagcccuaug cgaauuugaa      540

aacauaguaa caucaaaaaa aguaauaauc ccaacauacu uaagaucgau cucagucaga      600

aacaaagacc uaaauacacu cgaaaacaua acaacaacag aauuuaaaaa cgcaauaaca      660

aacgcaaaaa uaauaccaua cucaggacua cuccuaguaa uaacaguaac agacaacaaa      720

ggagcauuca aauacauaaa accacaauca caauucaucg uagaccucgg agcauaccua      780

gaaaaagaau caauauacua cguaacaaca aacuggaaac acaccgccac aagauucgca      840

auaaaaccca uggaagacua aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9892
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9892
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaccu acgucaacaa acuacacgaa      120

ggcucaaccu acaccgccgc cguccaauac aacguccucg aaaaagacga cgaccccgcc      180

ucccuaacca ucuggguucc cauguuccaa ucauccaugc ccgccgaccu ccucauaaaa      240

gaacuagcca acgucaacau ccuagucaaa caaaucagca cccccaaagg ccccucccuc      300

cgcguaauga ucaacucccg cuccgccguc cuagcccaaa ugcccuccaa auuuacaauc      360

ugcgccaacg ucucccucga cgaacgcuca aaacucgccu acgacgucac cacacccugc      420

gaaaucaaag ccugcucccu caccugccuc aaaagcaaaa auaugcuaac caccgucaaa      480

gaccuuacca ugaaaacccu caaccccacu cacgacauca uagcccucug cgaauuugaa      540

aacaucguca ccuccaaaaa agucaucauc cccacauacc uccgcuccau cuccguccgc      600

aacaaagacc ucaacacccu cgaaaacauc accaccaccg aauuuaaaaa cgccaucacc      660

aacgccaaaa ucauccccua cuccggccuc cuccucguca ucaccguuac cgacaacaaa      720

ggcgccuuca aauacaucaa accccaaucc caauucaucg ucgaccucgg agccuaccuu      780

gaaaaagagu ccaucuacua cgucaccacc aacuggaaac acaccgccac ccgauucgcc      840

aucaaaccca uggaagacua aggacuagug uccaccuguc ccuccugggc ugcuggauug      900

ucucguuuuc cugccaaaua aacaggauca gcgcuuuaca gaucuaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1020

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1073


<210>  9893
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9893
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acgugaacaa gcuucacgaa      120

ggcuccacau acacagcugc uguucaauac aaugucuuag aaaaagacga ugacccugca      180

ucacuuacaa uaugggugcc cauguuccaa ucaucuaugc cagcagauuu acuuauaaaa      240

gaacuagcua augucaacau acuagugaaa caaauaucca cacccaaggg accuucacua      300

agagucauga uaaacucaag aagugcagug cuagcacaaa ugcccagcaa auuuaccaua      360

ugcgcuaaug uguccuugga ugaaagaagc aaacuagcau augauguaac cacacccugu      420

gaaaucaagg cauguagucu aacaugccua aaaucaaaaa auauguugac uacaguuaaa      480

gaucucacua ugaagacacu caacccuaca caugauauua uugcuuuaug ugaauuugaa      540

aacauaguaa caucaaaaaa agucauaaua ccaacauacc uaagauccau cagugucaga      600

aauaaagauc ugaacacacu ugaaaauaua acaaccacug aauucaaaaa ugcuaucaca      660

aaugcaaaaa ucaucccuua cucaggauua cuauuaguca ucacagugac ugacaacaaa      720

ggagcauuca aauacauaaa gccacaaagu caauucauag uagaucuugg agcuuaccua      780

gaaaaagaaa guauauauua uguuaccaca aauuggaagc acacagcuac acgauuugca      840

aucaaaccca uggaagauua aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9894
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9894
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acacggccgc cguccaguac aacgugcucg agaaggacga cgaccccgcg      180

ucccugacca ucugggugcc gauguuccag agcuccaugc ccgccgaccu gcucaucaag      240

gagcuggcca acgucaacau ccuggugaag cagaucagca cccccaaggg gcccucccuc      300

cgcgugauga ucaacagccg guccgccguc cuggcccaga ugccgagcaa guucaccauc      360

ugcgcgaacg ugucccugga cgagcgcagc aagcucgccu acgacgugac gacccccugc      420

gagaucaagg ccugcucccu gaccugccuc aagagcaaga acaugcugac cacggucaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguga cguccaagaa ggugaucauc cccaccuacc ugcggagcau cuccguccgc      600

aacaaggacc ugaacacccu cgagaacauc accacgaccg aguucaagaa cgcgaucacc      660

aacgccaaga ucaucccgua cagcggccug cugcucguga ucaccgugac ggacaacaag      720

ggggccuuca aguacaucaa gccccagucc caguucaucg ucgaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac gcgguucgcg      840

aucaagccca uggaggacug aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9895
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9895
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgucaacaa gcuccacgag      120

ggcuccaccu acaccgccgc cguccaguac aacguccucg agaaggacga cgaccccgcc      180

ucccucacca ucuggguccc cauguuccag uccuccaugc ccgccgaccu ccucaucaag      240

gagcucgcca acgucaacau ccucgucaag cagaucucca cccccaaggg ccccucccuc      300

cgcgucauga ucaacucccg cuccgccguc cucgcccaga ugcccuccaa guucaccauc      360

ugcgccaacg ucucccucga cgagcgcucc aagcucgccu acgacgucac cacccccugc      420

gagaucaagg ccugcucccu caccugccuc aaguccaaga acaugcucac caccgucaag      480

gaccucacca ugaagacccu caaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguca ccuccaagaa ggucaucauc cccaccuacc uccgcuccau cuccguccgc      600

aacaaggacc ucaacacccu cgagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cuccggccuc cuccucguca ucaccgucac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagucc caguucaucg ucgaccucgg cgccuaccuc      780

gagaaggagu ccaucuacua cgucaccacc aacuggaagc acaccgccac ccgcuucgcc      840

aucaagccca uggaggacug aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9896
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9896
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacugccgc uguccaguac aauguucucg agaaagacga ugaccccgca      180

ucccuuacga ucugggugcc uauguuccaa ucuucaaugc cagccgaucu guugauuaag      240

gaauuagcga acguaaauau acuggugaaa cagaucagua ccccgaaggg gcccagccua      300

agagucauga uuaacuccag gucugcugug cucgcccaga ugccuucgaa auuuacaauc      360

ugcgcaaaug uuucacugga cgagcggagc aaacuugccu augaugugac uaccccaugu      420

gaaauuaagg cuugcagucu gacauguuug aaguccaaga acaugcucac cacugucaaa      480

gaccugacaa ugaagacccu gaaucccacg caugauauca uagcacucug cgaguucgag      540

aacaucguga cuucuaaaaa gguaauuauc ccuaccuacu uacgcagcau uuccguucga      600

aauaaggacc ugaacacacu ugaaaauauc acuaccacag aguuuaaaaa cgccauaacc      660

aaugcuaaga uuaucccaua uucaggauug cugcuaguga uuacggucac ugauaacaaa      720

ggugccuuca aguacaucaa accccagagu caauuuaucg uggaccucgg cgcguaucug      780

gaaaaggaga gcauuuacua cgugacaacc aauuggaaac acacugcaac acguuucgcc      840

auaaagccua uggaggauug aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9897
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9897
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acaccgccgc cgugcaguac aacgugcugg agaaggacga cgaccccgcc      180

agccugacca ucugggugcc cauguuccag agcagcaugc ccgccgaccu gcugaucaag      240

gagcuggcca acgugaacau ccuggugaag cagaucagca cccccaaggg ccccagccug      300

agagugauga ucaacagcag aagcgccgug cuggcccaga ugcccagcaa guucaccauc      360

ugcgccaacg ugagccugga cgagagaagc aagcuggccu acgacgugac cacccccugc      420

gagaucaagg ccugcagccu gaccugccug aagagcaaga acaugcugac caccgugaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccugug cgaguucgag      540

aacaucguga ccagcaagaa ggugaucauc cccaccuacc ugagaagcau cagcgugaga      600

aacaaggacc ugaacacccu ggagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cagcggccug cugcugguga ucaccgugac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagagc caguucaucg uggaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac cagauucgcc      840

aucaagccca uggaggacug aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9898
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9898
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacggccgc uguccaguac aauguucucg agaaagacga ugaccccgcc      180

ucccugacca ucugggugcc uauguuccaa ucuagcaugc cggcggaucu ucugauuaag      240

gaacucgcua acgugaauau ccuggucaaa cagauuucca cacccaaggg gccuucucuu      300

agagugauga ucaacagccg guccgccguu cuggcccaga ugcccucuaa auuuaccauu      360

ugcgcuaaug ugagccucga cgagcgcucc aagcuggccu augaugucac aaccccuugu      420

gaaaucaagg cuugcagccu gacaugucuc aaaucuaaga acaugcugac cacggugaaa      480

gaccuuacca ugaagacacu gaaucccacc caugauauca uugcccucug cgaguucgag      540

aacaucguua cauccaaaaa ggugauuauc ccuaccuacc ugagaagcau uucuguccgg      600

aauaaggacc uuaacacgcu ggaaaauauc acaaccacag aguuuaaaaa cgcgauuacc      660

aaugccaaga ucaucccgua uuccggacuc cugcugguga uuaccgugac agauaacaaa      720

ggcgcuuuca aguacaucaa accccagagc caauuuauug ucgaccucgg ggccuaucug      780

gaaaaggagu cuaucuacua cguuacgacc aauuggaaac acacagcuac ccgcuucgcc      840

auuaagccua uggaggauug aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9899
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9899
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acguaaacaa acuacacgaa      120

ggauccacau acacagcagc aguacaauac aacguacuag aaaaagacga cgacccagca      180

ucuuuaacca uauggguacc aauguuccaa ucaucaaugc cagcagaccu cuuaauaaaa      240

gaacuagcaa acguaaacau ccuagucaaa caaauaucaa cacccaaagg accaucccuc      300

agaguaauga ucaacucaag aucagcagua cuagcacaaa ugccaucaaa auucacaaua      360

ugcgccaacg uuucuuuaga cgaacgauca aaauuagccu acgacguaac aacacccugc      420

gaaauaaaag caugcucacu aacaugccua aaaucaaaaa acaugcucac uacaguaaaa      480

gaccuaacca ugaaaacacu caacccaaca cacgacauaa uagcccuaug cgaauuugaa      540

aacauaguaa caucaaaaaa aguaauaauc ccaacauacu uaagaucgau cucagucaga      600

aacaaagacc uaaauacacu cgaaaacaua acaacaacag aauuuaaaaa cgcaauaaca      660

aacgcaaaaa uaauaccaua cucaggacua cuccuaguaa uaacaguaac agacaacaaa      720

ggagcauuca aauacauaaa accacaauca caauucaucg uagaccucgg agcauaccua      780

gaaaaagaau caauauacua cguaacaaca aacuggaaac acaccgccac aagauucgca      840

auaaaaccca uggaagacua aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9900
<211>  1140
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9900
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaccu acgucaacaa acuacacgaa      120

ggcucaaccu acaccgccgc cguccaauac aacguccucg aaaaagacga cgaccccgcc      180

ucccuaacca ucuggguucc cauguuccaa ucauccaugc ccgccgaccu ccucauaaaa      240

gaacuagcca acgucaacau ccuagucaaa caaaucagca cccccaaagg ccccucccuc      300

cgcguaauga ucaacucccg cuccgccguc cuagcccaaa ugcccuccaa auuuacaauc      360

ugcgccaacg ucucccucga cgaacgcuca aaacucgccu acgacgucac cacacccugc      420

gaaaucaaag ccugcucccu caccugccuc aaaagcaaaa auaugcuaac caccgucaaa      480

gaccuuacca ugaaaacccu caaccccacu cacgacauca uagcccucug cgaauuugaa      540

aacaucguca ccuccaaaaa agucaucauc cccacauacc uccgcuccau cuccguccgc      600

aacaaagacc ucaacacccu cgaaaacauc accaccaccg aauuuaaaaa cgccaucacc      660

aacgccaaaa ucauccccua cuccggccuc cuccucguca ucaccguuac cgacaacaaa      720

ggcgccuuca aauacaucaa accccaaucc caauucaucg ucgaccucgg agccuaccuu      780

gaaaaagagu ccaucuacua cgucaccacc aacuggaaac acaccgccac ccgauucgcc      840

aucaaaccca uggaagacua aggacuagua cuggcugcau cucccuuucc ucuguccucc      900

auccuucucc caggauggug aagggggacc ugguacccag ugauccccac cccaggaucc      960

uaaaucauga cuuaccugcu aauaaaaacu cauuggaaaa gugagaagau cuaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1080

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1140


<210>  9901
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9901
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acgugaacaa gcuucacgaa      120

ggcuccacau acacagcugc uguucaauac aaugucuuag aaaaagacga ugacccugca      180

ucacuuacaa uaugggugcc cauguuccaa ucaucuaugc cagcagauuu acuuauaaaa      240

gaacuagcua augucaacau acuagugaaa caaauaucca cacccaaggg accuucacua      300

agagucauga uaaacucaag aagugcagug cuagcacaaa ugcccagcaa auuuaccaua      360

ugcgcuaaug uguccuugga ugaaagaagc aaacuagcau augauguaac cacacccugu      420

gaaaucaagg cauguagucu aacaugccua aaaucaaaaa auauguugac uacaguuaaa      480

gaucucacua ugaagacacu caacccuaca caugauauua uugcuuuaug ugaauuugaa      540

aacauaguaa caucaaaaaa agucauaaua ccaacauacc uaagauccau cagugucaga      600

aauaaagauc ugaacacacu ugaaaauaua acaaccacug aauucaaaaa ugcuaucaca      660

aaugcaaaaa ucaucccuua cucaggauua cuauuaguca ucacagugac ugacaacaaa      720

ggagcauuca aauacauaaa gccacaaagu caauucauag uagaucuugg agcuuaccua      780

gaaaaagaaa guauauauua uguuaccaca aauuggaagc acacagcuac acgauuugca      840

aucaaaccca uggaagauua aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9902
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9902
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acacggccgc cguccaguac aacgugcucg agaaggacga cgaccccgcg      180

ucccugacca ucugggugcc gauguuccag agcuccaugc ccgccgaccu gcucaucaag      240

gagcuggcca acgucaacau ccuggugaag cagaucagca cccccaaggg gcccucccuc      300

cgcgugauga ucaacagccg guccgccguc cuggcccaga ugccgagcaa guucaccauc      360

ugcgcgaacg ugucccugga cgagcgcagc aagcucgccu acgacgugac gacccccugc      420

gagaucaagg ccugcucccu gaccugccuc aagagcaaga acaugcugac cacggucaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguga cguccaagaa ggugaucauc cccaccuacc ugcggagcau cuccguccgc      600

aacaaggacc ugaacacccu cgagaacauc accacgaccg aguucaagaa cgcgaucacc      660

aacgccaaga ucaucccgua cagcggccug cugcucguga ucaccgugac ggacaacaag      720

ggggccuuca aguacaucaa gccccagucc caguucaucg ucgaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac gcgguucgcg      840

aucaagccca uggaggacug aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9903
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9903
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgucaacaa gcuccacgag      120

ggcuccaccu acaccgccgc cguccaguac aacguccucg agaaggacga cgaccccgcc      180

ucccucacca ucuggguccc cauguuccag uccuccaugc ccgccgaccu ccucaucaag      240

gagcucgcca acgucaacau ccucgucaag cagaucucca cccccaaggg ccccucccuc      300

cgcgucauga ucaacucccg cuccgccguc cucgcccaga ugcccuccaa guucaccauc      360

ugcgccaacg ucucccucga cgagcgcucc aagcucgccu acgacgucac cacccccugc      420

gagaucaagg ccugcucccu caccugccuc aaguccaaga acaugcucac caccgucaag      480

gaccucacca ugaagacccu caaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguca ccuccaagaa ggucaucauc cccaccuacc uccgcuccau cuccguccgc      600

aacaaggacc ucaacacccu cgagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cuccggccuc cuccucguca ucaccgucac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagucc caguucaucg ucgaccucgg cgccuaccuc      780

gagaaggagu ccaucuacua cgucaccacc aacuggaagc acaccgccac ccgcuucgcc      840

aucaagccca uggaggacug aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9904
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9904
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacugccgc uguccaguac aauguucucg agaaagacga ugaccccgca      180

ucccuuacga ucugggugcc uauguuccaa ucuucaaugc cagccgaucu guugauuaag      240

gaauuagcga acguaaauau acuggugaaa cagaucagua ccccgaaggg gcccagccua      300

agagucauga uuaacuccag gucugcugug cucgcccaga ugccuucgaa auuuacaauc      360

ugcgcaaaug uuucacugga cgagcggagc aaacuugccu augaugugac uaccccaugu      420

gaaauuaagg cuugcagucu gacauguuug aaguccaaga acaugcucac cacugucaaa      480

gaccugacaa ugaagacccu gaaucccacg caugauauca uagcacucug cgaguucgag      540

aacaucguga cuucuaaaaa gguaauuauc ccuaccuacu uacgcagcau uuccguucga      600

aauaaggacc ugaacacacu ugaaaauauc acuaccacag aguuuaaaaa cgccauaacc      660

aaugcuaaga uuaucccaua uucaggauug cugcuaguga uuacggucac ugauaacaaa      720

ggugccuuca aguacaucaa accccagagu caauuuaucg uggaccucgg cgcguaucug      780

gaaaaggaga gcauuuacua cgugacaacc aauuggaaac acacugcaac acguuucgcc      840

auaaagccua uggaggauug aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9905
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9905
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acaccgccgc cgugcaguac aacgugcugg agaaggacga cgaccccgcc      180

agccugacca ucugggugcc cauguuccag agcagcaugc ccgccgaccu gcugaucaag      240

gagcuggcca acgugaacau ccuggugaag cagaucagca cccccaaggg ccccagccug      300

agagugauga ucaacagcag aagcgccgug cuggcccaga ugcccagcaa guucaccauc      360

ugcgccaacg ugagccugga cgagagaagc aagcuggccu acgacgugac cacccccugc      420

gagaucaagg ccugcagccu gaccugccug aagagcaaga acaugcugac caccgugaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccugug cgaguucgag      540

aacaucguga ccagcaagaa ggugaucauc cccaccuacc ugagaagcau cagcgugaga      600

aacaaggacc ugaacacccu ggagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cagcggccug cugcugguga ucaccgugac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagagc caguucaucg uggaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac cagauucgcc      840

aucaagccca uggaggacug aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9906
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9906
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacggccgc uguccaguac aauguucucg agaaagacga ugaccccgcc      180

ucccugacca ucugggugcc uauguuccaa ucuagcaugc cggcggaucu ucugauuaag      240

gaacucgcua acgugaauau ccuggucaaa cagauuucca cacccaaggg gccuucucuu      300

agagugauga ucaacagccg guccgccguu cuggcccaga ugcccucuaa auuuaccauu      360

ugcgcuaaug ugagccucga cgagcgcucc aagcuggccu augaugucac aaccccuugu      420

gaaaucaagg cuugcagccu gacaugucuc aaaucuaaga acaugcugac cacggugaaa      480

gaccuuacca ugaagacacu gaaucccacc caugauauca uugcccucug cgaguucgag      540

aacaucguua cauccaaaaa ggugauuauc ccuaccuacc ugagaagcau uucuguccgg      600

aauaaggacc uuaacacgcu ggaaaauauc acaaccacag aguuuaaaaa cgcgauuacc      660

aaugccaaga ucaucccgua uuccggacuc cugcugguga uuaccgugac agauaacaaa      720

ggcgcuuuca aguacaucaa accccagagc caauuuauug ucgaccucgg ggccuaucug      780

gaaaaggagu cuaucuacua cguuacgacc aauuggaaac acacagcuac ccgcuucgcc      840

auuaagccua uggaggauug aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9907
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9907
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acguaaacaa acuacacgaa      120

ggauccacau acacagcagc aguacaauac aacguacuag aaaaagacga cgacccagca      180

ucuuuaacca uauggguacc aauguuccaa ucaucaaugc cagcagaccu cuuaauaaaa      240

gaacuagcaa acguaaacau ccuagucaaa caaauaucaa cacccaaagg accaucccuc      300

agaguaauga ucaacucaag aucagcagua cuagcacaaa ugccaucaaa auucacaaua      360

ugcgccaacg uuucuuuaga cgaacgauca aaauuagccu acgacguaac aacacccugc      420

gaaauaaaag caugcucacu aacaugccua aaaucaaaaa acaugcucac uacaguaaaa      480

gaccuaacca ugaaaacacu caacccaaca cacgacauaa uagcccuaug cgaauuugaa      540

aacauaguaa caucaaaaaa aguaauaauc ccaacauacu uaagaucgau cucagucaga      600

aacaaagacc uaaauacacu cgaaaacaua acaacaacag aauuuaaaaa cgcaauaaca      660

aacgcaaaaa uaauaccaua cucaggacua cuccuaguaa uaacaguaac agacaacaaa      720

ggagcauuca aauacauaaa accacaauca caauucaucg uagaccucgg agcauaccua      780

gaaaaagaau caauauacua cguaacaaca aacuggaaac acaccgccac aagauucgca      840

auaaaaccca uggaagacua aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9908
<211>  1356
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9908
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaccu acgucaacaa acuacacgaa      120

ggcucaaccu acaccgccgc cguccaauac aacguccucg aaaaagacga cgaccccgcc      180

ucccuaacca ucuggguucc cauguuccaa ucauccaugc ccgccgaccu ccucauaaaa      240

gaacuagcca acgucaacau ccuagucaaa caaaucagca cccccaaagg ccccucccuc      300

cgcguaauga ucaacucccg cuccgccguc cuagcccaaa ugcccuccaa auuuacaauc      360

ugcgccaacg ucucccucga cgaacgcuca aaacucgccu acgacgucac cacacccugc      420

gaaaucaaag ccugcucccu caccugccuc aaaagcaaaa auaugcuaac caccgucaaa      480

gaccuuacca ugaaaacccu caaccccacu cacgacauca uagcccucug cgaauuugaa      540

aacaucguca ccuccaaaaa agucaucauc cccacauacc uccgcuccau cuccguccgc      600

aacaaagacc ucaacacccu cgaaaacauc accaccaccg aauuuaaaaa cgccaucacc      660

aacgccaaaa ucauccccua cuccggccuc cuccucguca ucaccguuac cgacaacaaa      720

ggcgccuuca aauacaucaa accccaaucc caauucaucg ucgaccucgg agccuaccuu      780

gaaaaagagu ccaucuacua cgucaccacc aacuggaaac acaccgccac ccgauucgcc      840

aucaaaccca uggaagacua aggacuagug aagggaacac ccaaauuuaa uucagccuua      900

agcacaauua auuaagagug aaacguaauu guacaagcag uuggucaccc accauagggc      960

augaucaaca ccgcaaccuu uccuuuuucc cccagugauu cugaaaaacc ccucuucccu     1020

ucagcuugcu uagauguucc aaauuuagua agcuuaaggc ggccuacaga agaaaaagaa     1080

aaaaaaggcc acaaaaguuc ccucucacuu ucaguaaaua aaauaaaagc agcaacagaa     1140

auaaagaaau aaaugaaauu caaaaugaaa uaaauauugu guugugcagc auuaaaaaau     1200

caauaaaaau uaaaaaugag caagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1320

ccccccccaa aggcucuuuu cagagccacc agaauu                               1356


<210>  9909
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9909
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acgugaacaa gcuucacgaa      120

ggcuccacau acacagcugc uguucaauac aaugucuuag aaaaagacga ugacccugca      180

ucacuuacaa uaugggugcc cauguuccaa ucaucuaugc cagcagauuu acuuauaaaa      240

gaacuagcua augucaacau acuagugaaa caaauaucca cacccaaggg accuucacua      300

agagucauga uaaacucaag aagugcagug cuagcacaaa ugcccagcaa auuuaccaua      360

ugcgcuaaug uguccuugga ugaaagaagc aaacuagcau augauguaac cacacccugu      420

gaaaucaagg cauguagucu aacaugccua aaaucaaaaa auauguugac uacaguuaaa      480

gaucucacua ugaagacacu caacccuaca caugauauua uugcuuuaug ugaauuugaa      540

aacauaguaa caucaaaaaa agucauaaua ccaacauacc uaagauccau cagugucaga      600

aauaaagauc ugaacacacu ugaaaauaua acaaccacug aauucaaaaa ugcuaucaca      660

aaugcaaaaa ucaucccuua cucaggauua cuauuaguca ucacagugac ugacaacaaa      720

ggagcauuca aauacauaaa gccacaaagu caauucauag uagaucuugg agcuuaccua      780

gaaaaagaaa guauauauua uguuaccaca aauuggaagc acacagcuac acgauuugca      840

aucaaaccca uggaagauua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9910
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9910
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acacggccgc cguccaguac aacgugcucg agaaggacga cgaccccgcg      180

ucccugacca ucugggugcc gauguuccag agcuccaugc ccgccgaccu gcucaucaag      240

gagcuggcca acgucaacau ccuggugaag cagaucagca cccccaaggg gcccucccuc      300

cgcgugauga ucaacagccg guccgccguc cuggcccaga ugccgagcaa guucaccauc      360

ugcgcgaacg ugucccugga cgagcgcagc aagcucgccu acgacgugac gacccccugc      420

gagaucaagg ccugcucccu gaccugccuc aagagcaaga acaugcugac cacggucaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguga cguccaagaa ggugaucauc cccaccuacc ugcggagcau cuccguccgc      600

aacaaggacc ugaacacccu cgagaacauc accacgaccg aguucaagaa cgcgaucacc      660

aacgccaaga ucaucccgua cagcggccug cugcucguga ucaccgugac ggacaacaag      720

ggggccuuca aguacaucaa gccccagucc caguucaucg ucgaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac gcgguucgcg      840

aucaagccca uggaggacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9911
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9911
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgucaacaa gcuccacgag      120

ggcuccaccu acaccgccgc cguccaguac aacguccucg agaaggacga cgaccccgcc      180

ucccucacca ucuggguccc cauguuccag uccuccaugc ccgccgaccu ccucaucaag      240

gagcucgcca acgucaacau ccucgucaag cagaucucca cccccaaggg ccccucccuc      300

cgcgucauga ucaacucccg cuccgccguc cucgcccaga ugcccuccaa guucaccauc      360

ugcgccaacg ucucccucga cgagcgcucc aagcucgccu acgacgucac cacccccugc      420

gagaucaagg ccugcucccu caccugccuc aaguccaaga acaugcucac caccgucaag      480

gaccucacca ugaagacccu caaccccacc cacgacauca ucgcccucug cgaguucgag      540

aacaucguca ccuccaagaa ggucaucauc cccaccuacc uccgcuccau cuccguccgc      600

aacaaggacc ucaacacccu cgagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cuccggccuc cuccucguca ucaccgucac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagucc caguucaucg ucgaccucgg cgccuaccuc      780

gagaaggagu ccaucuacua cgucaccacc aacuggaagc acaccgccac ccgcuucgcc      840

aucaagccca uggaggacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9912
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9912
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacugccgc uguccaguac aauguucucg agaaagacga ugaccccgca      180

ucccuuacga ucugggugcc uauguuccaa ucuucaaugc cagccgaucu guugauuaag      240

gaauuagcga acguaaauau acuggugaaa cagaucagua ccccgaaggg gcccagccua      300

agagucauga uuaacuccag gucugcugug cucgcccaga ugccuucgaa auuuacaauc      360

ugcgcaaaug uuucacugga cgagcggagc aaacuugccu augaugugac uaccccaugu      420

gaaauuaagg cuugcagucu gacauguuug aaguccaaga acaugcucac cacugucaaa      480

gaccugacaa ugaagacccu gaaucccacg caugauauca uagcacucug cgaguucgag      540

aacaucguga cuucuaaaaa gguaauuauc ccuaccuacu uacgcagcau uuccguucga      600

aauaaggacc ugaacacacu ugaaaauauc acuaccacag aguuuaaaaa cgccauaacc      660

aaugcuaaga uuaucccaua uucaggauug cugcuaguga uuacggucac ugauaacaaa      720

ggugccuuca aguacaucaa accccagagu caauuuaucg uggaccucgg cgcguaucug      780

gaaaaggaga gcauuuacua cgugacaacc aauuggaaac acacugcaac acguuucgcc      840

auaaagccua uggaggauug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9913
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9913
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgag      120

ggcagcaccu acaccgccgc cgugcaguac aacgugcugg agaaggacga cgaccccgcc      180

agccugacca ucugggugcc cauguuccag agcagcaugc ccgccgaccu gcugaucaag      240

gagcuggcca acgugaacau ccuggugaag cagaucagca cccccaaggg ccccagccug      300

agagugauga ucaacagcag aagcgccgug cuggcccaga ugcccagcaa guucaccauc      360

ugcgccaacg ugagccugga cgagagaagc aagcuggccu acgacgugac cacccccugc      420

gagaucaagg ccugcagccu gaccugccug aagagcaaga acaugcugac caccgugaag      480

gaccugacca ugaagacccu gaaccccacc cacgacauca ucgcccugug cgaguucgag      540

aacaucguga ccagcaagaa ggugaucauc cccaccuacc ugagaagcau cagcgugaga      600

aacaaggacc ugaacacccu ggagaacauc accaccaccg aguucaagaa cgccaucacc      660

aacgccaaga ucauccccua cagcggccug cugcugguga ucaccgugac cgacaacaag      720

ggcgccuuca aguacaucaa gccccagagc caguucaucg uggaccuggg cgccuaccug      780

gagaaggaga gcaucuacua cgugaccacc aacuggaagc acaccgccac cagauucgcc      840

aucaagccca uggaggacug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9914
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9914
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaccu acgugaacaa gcugcacgaa      120

ggcagcacau auacggccgc uguccaguac aauguucucg agaaagacga ugaccccgcc      180

ucccugacca ucugggugcc uauguuccaa ucuagcaugc cggcggaucu ucugauuaag      240

gaacucgcua acgugaauau ccuggucaaa cagauuucca cacccaaggg gccuucucuu      300

agagugauga ucaacagccg guccgccguu cuggcccaga ugcccucuaa auuuaccauu      360

ugcgcuaaug ugagccucga cgagcgcucc aagcuggccu augaugucac aaccccuugu      420

gaaaucaagg cuugcagccu gacaugucuc aaaucuaaga acaugcugac cacggugaaa      480

gaccuuacca ugaagacacu gaaucccacc caugauauca uugcccucug cgaguucgag      540

aacaucguua cauccaaaaa ggugauuauc ccuaccuacc ugagaagcau uucuguccgg      600

aauaaggacc uuaacacgcu ggaaaauauc acaaccacag aguuuaaaaa cgcgauuacc      660

aaugccaaga ucaucccgua uuccggacuc cugcugguga uuaccgugac agauaacaaa      720

ggcgcuuuca aguacaucaa accccagagc caauuuauug ucgaccucgg ggccuaucug      780

gaaaaggagu cuaucuacua cguuacgacc aauuggaaac acacagcuac ccgcuucgcc      840

auuaagccua uggaggauug aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9915
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9915
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaacau acguaaacaa acuacacgaa      120

ggauccacau acacagcagc aguacaauac aacguacuag aaaaagacga cgacccagca      180

ucuuuaacca uauggguacc aauguuccaa ucaucaaugc cagcagaccu cuuaauaaaa      240

gaacuagcaa acguaaacau ccuagucaaa caaauaucaa cacccaaagg accaucccuc      300

agaguaauga ucaacucaag aucagcagua cuagcacaaa ugccaucaaa auucacaaua      360

ugcgccaacg uuucuuuaga cgaacgauca aaauuagccu acgacguaac aacacccugc      420

gaaauaaaag caugcucacu aacaugccua aaaucaaaaa acaugcucac uacaguaaaa      480

gaccuaacca ugaaaacacu caacccaaca cacgacauaa uagcccuaug cgaauuugaa      540

aacauaguaa caucaaaaaa aguaauaauc ccaacauacu uaagaucgau cucagucaga      600

aacaaagacc uaaauacacu cgaaaacaua acaacaacag aauuuaaaaa cgcaauaaca      660

aacgcaaaaa uaauaccaua cucaggacua cuccuaguaa uaacaguaac agacaacaaa      720

ggagcauuca aauacauaaa accacaauca caauucaucg uagaccucgg agcauaccua      780

gaaaaagaau caauauacua cguaacaaca aacuggaaac acaccgccac aagauucgca      840

auaaaaccca uggaagacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9916
<211>  1136
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9916
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaccu acgucaacaa acuacacgaa      120

ggcucaaccu acaccgccgc cguccaauac aacguccucg aaaaagacga cgaccccgcc      180

ucccuaacca ucuggguucc cauguuccaa ucauccaugc ccgccgaccu ccucauaaaa      240

gaacuagcca acgucaacau ccuagucaaa caaaucagca cccccaaagg ccccucccuc      300

cgcguaauga ucaacucccg cuccgccguc cuagcccaaa ugcccuccaa auuuacaauc      360

ugcgccaacg ucucccucga cgaacgcuca aaacucgccu acgacgucac cacacccugc      420

gaaaucaaag ccugcucccu caccugccuc aaaagcaaaa auaugcuaac caccgucaaa      480

gaccuuacca ugaaaacccu caaccccacu cacgacauca uagcccucug cgaauuugaa      540

aacaucguca ccuccaaaaa agucaucauc cccacauacc uccgcuccau cuccguccgc      600

aacaaagacc ucaacacccu cgaaaacauc accaccaccg aauuuaaaaa cgccaucacc      660

aacgccaaaa ucauccccua cuccggccuc cuccucguca ucaccguuac cgacaacaaa      720

ggcgccuuca aauacaucaa accccaaucc caauucaucg ucgaccucgg agccuaccuu      780

gaaaaagagu ccaucuacua cgucaccacc aacuggaaac acaccgccac ccgauucgcc      840

aucaaaccca uggaagacua aggacuagug gaagcauuuu ccuggcugau uaaaagaaau      900

uacucagcua uggucaucug uuccuguuag aaggcuaugc agcauauuau auacuaugcg      960

cauguuauga aaugcauaau aaaaaauuuu aaaaaaucua aaagaucuaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc     1080

cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu         1136


<210>  9917
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9917
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg ugaacaagcu ucacgaaggc uccacauaca      120

cagcugcugu ucaauacaau gucuuagaaa aagacgauga cccugcauca cuuacaauau      180

gggugcccau guuccaauca ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug      240

ucaacauacu agugaaacaa auauccacac ccaagggacc uucacuaaga gucaugauaa      300

acucaagaag ugcagugcua gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu      360

ccuuggauga aagaagcaaa cuagcauaug auguaaccac acccugugaa aucaaggcau      420

guagucuaac augccuaaaa ucaaaaaaua uguugacuac aguuaaagau cucacuauga      480

agacacucaa cccuacacau gauauuauug cuuuauguga auuugaaaac auaguaacau      540

caaaaaaagu cauaauacca acauaccuaa gauccaucag ugucagaaau aaagaucuga      600

acacacuuga aaauauaaca accacugaau ucaaaaaugc uaucacaaau gcaaaaauca      660

ucccuuacuc aggauuacua uuagucauca cagugacuga caacaaagga gcauucaaau      720

acauaaagcc acaaagucaa uucauaguag aucuuggagc uuaccuagaa aaagaaagua      780

uauauuaugu uaccacaaau uggaagcaca cagcuacacg auuugcaauc aaacccaugg      840

aagauuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9918
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9918
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

cggccgccgu ccaguacaac gugcucgaga aggacgacga ccccgcgucc cugaccaucu      180

gggugccgau guuccagagc uccaugcccg ccgaccugcu caucaaggag cuggccaacg      240

ucaacauccu ggugaagcag aucagcaccc ccaaggggcc cucccuccgc gugaugauca      300

acagccgguc cgccguccug gcccagaugc cgagcaaguu caccaucugc gcgaacgugu      360

cccuggacga gcgcagcaag cucgccuacg acgugacgac ccccugcgag aucaaggccu      420

gcucccugac cugccucaag agcaagaaca ugcugaccac ggucaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgugacgu      540

ccaagaaggu gaucaucccc accuaccugc ggagcaucuc cguccgcaac aaggaccuga      600

acacccucga gaacaucacc acgaccgagu ucaagaacgc gaucaccaac gccaagauca      660

ucccguacag cggccugcug cucgugauca ccgugacgga caacaagggg gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccacgcg guucgcgauc aagcccaugg      840

aggacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9919
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9919
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ucaacaagcu ccacgagggc uccaccuaca      120

ccgccgccgu ccaguacaac guccucgaga aggacgacga ccccgccucc cucaccaucu      180

ggguccccau guuccagucc uccaugcccg ccgaccuccu caucaaggag cucgccaacg      240

ucaacauccu cgucaagcag aucuccaccc ccaagggccc cucccuccgc gucaugauca      300

acucccgcuc cgccguccuc gcccagaugc ccuccaaguu caccaucugc gccaacgucu      360

cccucgacga gcgcuccaag cucgccuacg acgucaccac ccccugcgag aucaaggccu      420

gcucccucac cugccucaag uccaagaaca ugcucaccac cgucaaggac cucaccauga      480

agacccucaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgucaccu      540

ccaagaaggu caucaucccc accuaccucc gcuccaucuc cguccgcaac aaggaccuca      600

acacccucga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacuc cggccuccuc cucgucauca ccgucaccga caacaagggc gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accucggcgc cuaccucgag aaggagucca      780

ucuacuacgu caccaccaac uggaagcaca ccgccacccg cuucgccauc aagcccaugg      840

aggacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9920
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9920
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cugccgcugu ccaguacaau guucucgaga aagacgauga ccccgcaucc cuuacgaucu      180

gggugccuau guuccaaucu ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg      240

uaaauauacu ggugaaacag aucaguaccc cgaaggggcc cagccuaaga gucaugauua      300

acuccagguc ugcugugcuc gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu      360

cacuggacga gcggagcaaa cuugccuaug augugacuac cccaugugaa auuaaggcuu      420

gcagucugac auguuugaag uccaagaaca ugcucaccac ugucaaagac cugacaauga      480

agacccugaa ucccacgcau gauaucauag cacucugcga guucgagaac aucgugacuu      540

cuaaaaaggu aauuaucccu accuacuuac gcagcauuuc cguucgaaau aaggaccuga      600

acacacuuga aaauaucacu accacagagu uuaaaaacgc cauaaccaau gcuaagauua      660

ucccauauuc aggauugcug cuagugauua cggucacuga uaacaaaggu gccuucaagu      720

acaucaaacc ccagagucaa uuuaucgugg accucggcgc guaucuggaa aaggagagca      780

uuuacuacgu gacaaccaau uggaaacaca cugcaacacg uuucgccaua aagccuaugg      840

aggauugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9921
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9921
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

ccgccgccgu gcaguacaac gugcuggaga aggacgacga ccccgccagc cugaccaucu      180

gggugcccau guuccagagc agcaugcccg ccgaccugcu gaucaaggag cuggccaacg      240

ugaacauccu ggugaagcag aucagcaccc ccaagggccc cagccugaga gugaugauca      300

acagcagaag cgccgugcug gcccagaugc ccagcaaguu caccaucugc gccaacguga      360

gccuggacga gagaagcaag cuggccuacg acgugaccac ccccugcgag aucaaggccu      420

gcagccugac cugccugaag agcaagaaca ugcugaccac cgugaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccugugcga guucgagaac aucgugacca      540

gcaagaaggu gaucaucccc accuaccuga gaagcaucag cgugagaaac aaggaccuga      600

acacccugga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacag cggccugcug cuggugauca ccgugaccga caacaagggc gccuucaagu      720

acaucaagcc ccagagccag uucaucgugg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccaccag auucgccauc aagcccaugg      840

aggacugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9922
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9922
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cggccgcugu ccaguacaau guucucgaga aagacgauga ccccgccucc cugaccaucu      180

gggugccuau guuccaaucu agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg      240

ugaauauccu ggucaaacag auuuccacac ccaaggggcc uucucuuaga gugaugauca      300

acagccgguc cgccguucug gcccagaugc ccucuaaauu uaccauuugc gcuaauguga      360

gccucgacga gcgcuccaag cuggccuaug augucacaac cccuugugaa aucaaggcuu      420

gcagccugac augucucaaa ucuaagaaca ugcugaccac ggugaaagac cuuaccauga      480

agacacugaa ucccacccau gauaucauug cccucugcga guucgagaac aucguuacau      540

ccaaaaaggu gauuaucccu accuaccuga gaagcauuuc uguccggaau aaggaccuua      600

acacgcugga aaauaucaca accacagagu uuaaaaacgc gauuaccaau gccaagauca      660

ucccguauuc cggacuccug cuggugauua ccgugacaga uaacaaaggc gcuuucaagu      720

acaucaaacc ccagagccaa uuuauugucg accucggggc cuaucuggaa aaggagucua      780

ucuacuacgu uacgaccaau uggaaacaca cagcuacccg cuucgccauu aagccuaugg      840

aggauugagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9923
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9923
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg uaaacaaacu acacgaagga uccacauaca      120

cagcagcagu acaauacaac guacuagaaa aagacgacga cccagcaucu uuaaccauau      180

ggguaccaau guuccaauca ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg      240

uaaacauccu agucaaacaa auaucaacac ccaaaggacc aucccucaga guaaugauca      300

acucaagauc agcaguacua gcacaaaugc caucaaaauu cacaauaugc gccaacguuu      360

cuuuagacga acgaucaaaa uuagccuacg acguaacaac acccugcgaa auaaaagcau      420

gcucacuaac augccuaaaa ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga      480

aaacacucaa cccaacacac gacauaauag cccuaugcga auuugaaaac auaguaacau      540

caaaaaaagu aauaauccca acauacuuaa gaucgaucuc agucagaaac aaagaccuaa      600

auacacucga aaacauaaca acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa      660

uaccauacuc aggacuacuc cuaguaauaa caguaacaga caacaaagga gcauucaaau      720

acauaaaacc acaaucacaa uucaucguag accucggagc auaccuagaa aaagaaucaa      780

uauacuacgu aacaacaaac uggaaacaca ccgccacaag auucgcaaua aaacccaugg      840

aagacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9924
<211>  1127
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9924
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca      120

ccgccgccgu ccaauacaac guccucgaaa aagacgacga ccccgccucc cuaaccaucu      180

ggguucccau guuccaauca uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg      240

ucaacauccu agucaaacaa aucagcaccc ccaaaggccc cucccuccgc guaaugauca      300

acucccgcuc cgccguccua gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu      360

cccucgacga acgcucaaaa cucgccuacg acgucaccac acccugcgaa aucaaagccu      420

gcucccucac cugccucaaa agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga      480

aaacccucaa ccccacucac gacaucauag cccucugcga auuugaaaac aucgucaccu      540

ccaaaaaagu caucaucccc acauaccucc gcuccaucuc cguccgcaac aaagaccuca      600

acacccucga aaacaucacc accaccgaau uuaaaaacgc caucaccaac gccaaaauca      660

uccccuacuc cggccuccuc cucgucauca ccguuaccga caacaaaggc gccuucaaau      720

acaucaaacc ccaaucccaa uucaucgucg accucggagc cuaccuugaa aaagagucca      780

ucuacuacgu caccaccaac uggaaacaca ccgccacccg auucgccauc aaacccaugg      840

aagacuaagg acuaguacug gcugcaucuc ccuuuccucu guccuccauc cuucucccag      900

gauggugaag ggggaccugg uacccaguga uccccacccc aggauccuaa aucaugacuu      960

accugcuaau aaaaacucau uggaaaagug agaagaucua aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1080

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1127


<210>  9925
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9925
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg ugaacaagcu ucacgaaggc uccacauaca      120

cagcugcugu ucaauacaau gucuuagaaa aagacgauga cccugcauca cuuacaauau      180

gggugcccau guuccaauca ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug      240

ucaacauacu agugaaacaa auauccacac ccaagggacc uucacuaaga gucaugauaa      300

acucaagaag ugcagugcua gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu      360

ccuuggauga aagaagcaaa cuagcauaug auguaaccac acccugugaa aucaaggcau      420

guagucuaac augccuaaaa ucaaaaaaua uguugacuac aguuaaagau cucacuauga      480

agacacucaa cccuacacau gauauuauug cuuuauguga auuugaaaac auaguaacau      540

caaaaaaagu cauaauacca acauaccuaa gauccaucag ugucagaaau aaagaucuga      600

acacacuuga aaauauaaca accacugaau ucaaaaaugc uaucacaaau gcaaaaauca      660

ucccuuacuc aggauuacua uuagucauca cagugacuga caacaaagga gcauucaaau      720

acauaaagcc acaaagucaa uucauaguag aucuuggagc uuaccuagaa aaagaaagua      780

uauauuaugu uaccacaaau uggaagcaca cagcuacacg auuugcaauc aaacccaugg      840

aagauuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9926
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9926
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

cggccgccgu ccaguacaac gugcucgaga aggacgacga ccccgcgucc cugaccaucu      180

gggugccgau guuccagagc uccaugcccg ccgaccugcu caucaaggag cuggccaacg      240

ucaacauccu ggugaagcag aucagcaccc ccaaggggcc cucccuccgc gugaugauca      300

acagccgguc cgccguccug gcccagaugc cgagcaaguu caccaucugc gcgaacgugu      360

cccuggacga gcgcagcaag cucgccuacg acgugacgac ccccugcgag aucaaggccu      420

gcucccugac cugccucaag agcaagaaca ugcugaccac ggucaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgugacgu      540

ccaagaaggu gaucaucccc accuaccugc ggagcaucuc cguccgcaac aaggaccuga      600

acacccucga gaacaucacc acgaccgagu ucaagaacgc gaucaccaac gccaagauca      660

ucccguacag cggccugcug cucgugauca ccgugacgga caacaagggg gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccacgcg guucgcgauc aagcccaugg      840

aggacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9927
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9927
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ucaacaagcu ccacgagggc uccaccuaca      120

ccgccgccgu ccaguacaac guccucgaga aggacgacga ccccgccucc cucaccaucu      180

ggguccccau guuccagucc uccaugcccg ccgaccuccu caucaaggag cucgccaacg      240

ucaacauccu cgucaagcag aucuccaccc ccaagggccc cucccuccgc gucaugauca      300

acucccgcuc cgccguccuc gcccagaugc ccuccaaguu caccaucugc gccaacgucu      360

cccucgacga gcgcuccaag cucgccuacg acgucaccac ccccugcgag aucaaggccu      420

gcucccucac cugccucaag uccaagaaca ugcucaccac cgucaaggac cucaccauga      480

agacccucaa ccccacccac gacaucaucg cccucugcga guucgagaac aucgucaccu      540

ccaagaaggu caucaucccc accuaccucc gcuccaucuc cguccgcaac aaggaccuca      600

acacccucga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacuc cggccuccuc cucgucauca ccgucaccga caacaagggc gccuucaagu      720

acaucaagcc ccagucccag uucaucgucg accucggcgc cuaccucgag aaggagucca      780

ucuacuacgu caccaccaac uggaagcaca ccgccacccg cuucgccauc aagcccaugg      840

aggacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9928
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9928
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cugccgcugu ccaguacaau guucucgaga aagacgauga ccccgcaucc cuuacgaucu      180

gggugccuau guuccaaucu ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg      240

uaaauauacu ggugaaacag aucaguaccc cgaaggggcc cagccuaaga gucaugauua      300

acuccagguc ugcugugcuc gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu      360

cacuggacga gcggagcaaa cuugccuaug augugacuac cccaugugaa auuaaggcuu      420

gcagucugac auguuugaag uccaagaaca ugcucaccac ugucaaagac cugacaauga      480

agacccugaa ucccacgcau gauaucauag cacucugcga guucgagaac aucgugacuu      540

cuaaaaaggu aauuaucccu accuacuuac gcagcauuuc cguucgaaau aaggaccuga      600

acacacuuga aaauaucacu accacagagu uuaaaaacgc cauaaccaau gcuaagauua      660

ucccauauuc aggauugcug cuagugauua cggucacuga uaacaaaggu gccuucaagu      720

acaucaaacc ccagagucaa uuuaucgugg accucggcgc guaucuggaa aaggagagca      780

uuuacuacgu gacaaccaau uggaaacaca cugcaacacg uuucgccaua aagccuaugg      840

aggauugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9929
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9929
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgagggc agcaccuaca      120

ccgccgccgu gcaguacaac gugcuggaga aggacgacga ccccgccagc cugaccaucu      180

gggugcccau guuccagagc agcaugcccg ccgaccugcu gaucaaggag cuggccaacg      240

ugaacauccu ggugaagcag aucagcaccc ccaagggccc cagccugaga gugaugauca      300

acagcagaag cgccgugcug gcccagaugc ccagcaaguu caccaucugc gccaacguga      360

gccuggacga gagaagcaag cuggccuacg acgugaccac ccccugcgag aucaaggccu      420

gcagccugac cugccugaag agcaagaaca ugcugaccac cgugaaggac cugaccauga      480

agacccugaa ccccacccac gacaucaucg cccugugcga guucgagaac aucgugacca      540

gcaagaaggu gaucaucccc accuaccuga gaagcaucag cgugagaaac aaggaccuga      600

acacccugga gaacaucacc accaccgagu ucaagaacgc caucaccaac gccaagauca      660

uccccuacag cggccugcug cuggugauca ccgugaccga caacaagggc gccuucaagu      720

acaucaagcc ccagagccag uucaucgugg accugggcgc cuaccuggag aaggagagca      780

ucuacuacgu gaccaccaac uggaagcaca ccgccaccag auucgccauc aagcccaugg      840

aggacugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9930
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9930
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccuacg ugaacaagcu gcacgaaggc agcacauaua      120

cggccgcugu ccaguacaau guucucgaga aagacgauga ccccgccucc cugaccaucu      180

gggugccuau guuccaaucu agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg      240

ugaauauccu ggucaaacag auuuccacac ccaaggggcc uucucuuaga gugaugauca      300

acagccgguc cgccguucug gcccagaugc ccucuaaauu uaccauuugc gcuaauguga      360

gccucgacga gcgcuccaag cuggccuaug augucacaac cccuugugaa aucaaggcuu      420

gcagccugac augucucaaa ucuaagaaca ugcugaccac ggugaaagac cuuaccauga      480

agacacugaa ucccacccau gauaucauug cccucugcga guucgagaac aucguuacau      540

ccaaaaaggu gauuaucccu accuaccuga gaagcauuuc uguccggaau aaggaccuua      600

acacgcugga aaauaucaca accacagagu uuaaaaacgc gauuaccaau gccaagauca      660

ucccguauuc cggacuccug cuggugauua ccgugacaga uaacaaaggc gcuuucaagu      720

acaucaaacc ccagagccaa uuuauugucg accucggggc cuaucuggaa aaggagucua      780

ucuacuacgu uacgaccaau uggaaacaca cagcuacccg cuucgccauu aagccuaugg      840

aggauugagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9931
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9931
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacauacg uaaacaaacu acacgaagga uccacauaca      120

cagcagcagu acaauacaac guacuagaaa aagacgacga cccagcaucu uuaaccauau      180

ggguaccaau guuccaauca ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg      240

uaaacauccu agucaaacaa auaucaacac ccaaaggacc aucccucaga guaaugauca      300

acucaagauc agcaguacua gcacaaaugc caucaaaauu cacaauaugc gccaacguuu      360

cuuuagacga acgaucaaaa uuagccuacg acguaacaac acccugcgaa auaaaagcau      420

gcucacuaac augccuaaaa ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga      480

aaacacucaa cccaacacac gacauaauag cccuaugcga auuugaaaac auaguaacau      540

caaaaaaagu aauaauccca acauacuuaa gaucgaucuc agucagaaac aaagaccuaa      600

auacacucga aaacauaaca acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa      660

uaccauacuc aggacuacuc cuaguaauaa caguaacaga caacaaagga gcauucaaau      720

acauaaaacc acaaucacaa uucaucguag accucggagc auaccuagaa aaagaaucaa      780

uauacuacgu aacaacaaac uggaaacaca ccgccacaag auucgcaaua aaacccaugg      840

aagacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9932
<211>  1343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9932
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca      120

ccgccgccgu ccaauacaac guccucgaaa aagacgacga ccccgccucc cuaaccaucu      180

ggguucccau guuccaauca uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg      240

ucaacauccu agucaaacaa aucagcaccc ccaaaggccc cucccuccgc guaaugauca      300

acucccgcuc cgccguccua gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu      360

cccucgacga acgcucaaaa cucgccuacg acgucaccac acccugcgaa aucaaagccu      420

gcucccucac cugccucaaa agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga      480

aaacccucaa ccccacucac gacaucauag cccucugcga auuugaaaac aucgucaccu      540

ccaaaaaagu caucaucccc acauaccucc gcuccaucuc cguccgcaac aaagaccuca      600

acacccucga aaacaucacc accaccgaau uuaaaaacgc caucaccaac gccaaaauca      660

uccccuacuc cggccuccuc cucgucauca ccguuaccga caacaaaggc gccuucaaau      720

acaucaaacc ccaaucccaa uucaucgucg accucggagc cuaccuugaa aaagagucca      780

ucuacuacgu caccaccaac uggaaacaca ccgccacccg auucgccauc aaacccaugg      840

aagacuaagg acuagugaag ggaacaccca aauuuaauuc agccuuaagc acaauuaauu      900

aagagugaaa cguaauugua caagcaguug gucacccacc auagggcaug aucaacaccg      960

caaccuuucc uuuuuccccc agugauucug aaaaaccccu cuucccuuca gcuugcuuag     1020

auguuccaaa uuuaguaagc uuaaggcggc cuacagaaga aaaagaaaaa aaaggccaca     1080

aaaguucccu cucacuuuca guaaauaaaa uaaaagcagc aacagaaaua aagaaauaaa     1140

ugaaauucaa aaugaaauaa auauuguguu gugcagcauu aaaaaaucaa uaaaaauuaa     1200

aaaugagcaa gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1320

cucuuuucag agccaccaga auu                                             1343


<210>  9933
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9933
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cgugaacaag cuucacgaag gcuccacaua cacagcugcu      120

guucaauaca augucuuaga aaaagacgau gacccugcau cacuuacaau augggugccc      180

auguuccaau caucuaugcc agcagauuua cuuauaaaag aacuagcuaa ugucaacaua      240

cuagugaaac aaauauccac acccaaggga ccuucacuaa gagucaugau aaacucaaga      300

agugcagugc uagcacaaau gcccagcaaa uuuaccauau gcgcuaaugu guccuuggau      360

gaaagaagca aacuagcaua ugauguaacc acacccugug aaaucaaggc auguagucua      420

acaugccuaa aaucaaaaaa uauguugacu acaguuaaag aucucacuau gaagacacuc      480

aacccuacac augauauuau ugcuuuaugu gaauuugaaa acauaguaac aucaaaaaaa      540

gucauaauac caacauaccu aagauccauc agugucagaa auaaagaucu gaacacacuu      600

gaaaauauaa caaccacuga auucaaaaau gcuaucacaa augcaaaaau caucccuuac      660

ucaggauuac uauuagucau cacagugacu gacaacaaag gagcauucaa auacauaaag      720

ccacaaaguc aauucauagu agaucuugga gcuuaccuag aaaaagaaag uauauauuau      780

guuaccacaa auuggaagca cacagcuaca cgauuugcaa ucaaacccau ggaagauuaa      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9934
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9934
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua cacggccgcc      120

guccaguaca acgugcucga gaaggacgac gaccccgcgu cccugaccau cugggugccg      180

auguuccaga gcuccaugcc cgccgaccug cucaucaagg agcuggccaa cgucaacauc      240

cuggugaagc agaucagcac ccccaagggg cccucccucc gcgugaugau caacagccgg      300

uccgccgucc uggcccagau gccgagcaag uucaccaucu gcgcgaacgu gucccuggac      360

gagcgcagca agcucgccua cgacgugacg acccccugcg agaucaaggc cugcucccug      420

accugccuca agagcaagaa caugcugacc acggucaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgugac guccaagaag      540

gugaucaucc ccaccuaccu gcggagcauc uccguccgca acaaggaccu gaacacccuc      600

gagaacauca ccacgaccga guucaagaac gcgaucacca acgccaagau caucccguac      660

agcggccugc ugcucgugau caccgugacg gacaacaagg gggccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacg cgguucgcga ucaagcccau ggaggacuga      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9935
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9935
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgucaacaag cuccacgagg gcuccaccua caccgccgcc      120

guccaguaca acguccucga gaaggacgac gaccccgccu cccucaccau cugggucccc      180

auguuccagu ccuccaugcc cgccgaccuc cucaucaagg agcucgccaa cgucaacauc      240

cucgucaagc agaucuccac ccccaagggc cccucccucc gcgucaugau caacucccgc      300

uccgccgucc ucgcccagau gcccuccaag uucaccaucu gcgccaacgu cucccucgac      360

gagcgcucca agcucgccua cgacgucacc acccccugcg agaucaaggc cugcucccuc      420

accugccuca aguccaagaa caugcucacc accgucaagg accucaccau gaagacccuc      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgucac cuccaagaag      540

gucaucaucc ccaccuaccu ccgcuccauc uccguccgca acaaggaccu caacacccuc      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

uccggccucc uccucgucau caccgucacc gacaacaagg gcgccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccucggc gccuaccucg agaaggaguc caucuacuac      780

gucaccacca acuggaagca caccgccacc cgcuucgcca ucaagcccau ggaggacuga      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9936
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9936
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacugccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgcau cccuuacgau cugggugccu      180

auguuccaau cuucaaugcc agccgaucug uugauuaagg aauuagcgaa cguaaauaua      240

cuggugaaac agaucaguac cccgaagggg cccagccuaa gagucaugau uaacuccagg      300

ucugcugugc ucgcccagau gccuucgaaa uuuacaaucu gcgcaaaugu uucacuggac      360

gagcggagca aacuugccua ugaugugacu accccaugug aaauuaaggc uugcagucug      420

acauguuuga aguccaagaa caugcucacc acugucaaag accugacaau gaagacccug      480

aaucccacgc augauaucau agcacucugc gaguucgaga acaucgugac uucuaaaaag      540

guaauuaucc cuaccuacuu acgcagcauu uccguucgaa auaaggaccu gaacacacuu      600

gaaaauauca cuaccacaga guuuaaaaac gccauaacca augcuaagau uaucccauau      660

ucaggauugc ugcuagugau uacggucacu gauaacaaag gugccuucaa guacaucaaa      720

ccccagaguc aauuuaucgu ggaccucggc gcguaucugg aaaaggagag cauuuacuac      780

gugacaacca auuggaaaca cacugcaaca cguuucgcca uaaagccuau ggaggauuga      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9937
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9937
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua caccgccgcc      120

gugcaguaca acgugcugga gaaggacgac gaccccgcca gccugaccau cugggugccc      180

auguuccaga gcagcaugcc cgccgaccug cugaucaagg agcuggccaa cgugaacauc      240

cuggugaagc agaucagcac ccccaagggc cccagccuga gagugaugau caacagcaga      300

agcgccgugc uggcccagau gcccagcaag uucaccaucu gcgccaacgu gagccuggac      360

gagagaagca agcuggccua cgacgugacc acccccugcg agaucaaggc cugcagccug      420

accugccuga agagcaagaa caugcugacc accgugaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccugugc gaguucgaga acaucgugac cagcaagaag      540

gugaucaucc ccaccuaccu gagaagcauc agcgugagaa acaaggaccu gaacacccug      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

agcggccugc ugcuggugau caccgugacc gacaacaagg gcgccuucaa guacaucaag      720

ccccagagcc aguucaucgu ggaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacc agauucgcca ucaagcccau ggaggacuga      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9938
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9938
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacggccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgccu cccugaccau cugggugccu      180

auguuccaau cuagcaugcc ggcggaucuu cugauuaagg aacucgcuaa cgugaauauc      240

cuggucaaac agauuuccac acccaagggg ccuucucuua gagugaugau caacagccgg      300

uccgccguuc uggcccagau gcccucuaaa uuuaccauuu gcgcuaaugu gagccucgac      360

gagcgcucca agcuggccua ugaugucaca accccuugug aaaucaaggc uugcagccug      420

acaugucuca aaucuaagaa caugcugacc acggugaaag accuuaccau gaagacacug      480

aaucccaccc augauaucau ugcccucugc gaguucgaga acaucguuac auccaaaaag      540

gugauuaucc cuaccuaccu gagaagcauu ucuguccgga auaaggaccu uaacacgcug      600

gaaaauauca caaccacaga guuuaaaaac gcgauuacca augccaagau caucccguau      660

uccggacucc ugcuggugau uaccgugaca gauaacaaag gcgcuuucaa guacaucaaa      720

ccccagagcc aauuuauugu cgaccucggg gccuaucugg aaaaggaguc uaucuacuac      780

guuacgacca auuggaaaca cacagcuacc cgcuucgcca uuaagccuau ggaggauuga      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9939
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9939
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cguaaacaaa cuacacgaag gauccacaua cacagcagca      120

guacaauaca acguacuaga aaaagacgac gacccagcau cuuuaaccau auggguacca      180

auguuccaau caucaaugcc agcagaccuc uuaauaaaag aacuagcaaa cguaaacauc      240

cuagucaaac aaauaucaac acccaaagga ccaucccuca gaguaaugau caacucaaga      300

ucagcaguac uagcacaaau gccaucaaaa uucacaauau gcgccaacgu uucuuuagac      360

gaacgaucaa aauuagccua cgacguaaca acacccugcg aaauaaaagc augcucacua      420

acaugccuaa aaucaaaaaa caugcucacu acaguaaaag accuaaccau gaaaacacuc      480

aacccaacac acgacauaau agcccuaugc gaauuugaaa acauaguaac aucaaaaaaa      540

guaauaaucc caacauacuu aagaucgauc ucagucagaa acaaagaccu aaauacacuc      600

gaaaacauaa caacaacaga auuuaaaaac gcaauaacaa acgcaaaaau aauaccauac      660

ucaggacuac uccuaguaau aacaguaaca gacaacaaag gagcauucaa auacauaaaa      720

ccacaaucac aauucaucgu agaccucgga gcauaccuag aaaaagaauc aauauacuac      780

guaacaacaa acuggaaaca caccgccaca agauucgcaa uaaaacccau ggaagacuaa      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9940
<211>  1119
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9940
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaccua cgucaacaaa cuacacgaag gcucaaccua caccgccgcc      120

guccaauaca acguccucga aaaagacgac gaccccgccu cccuaaccau cuggguuccc      180

auguuccaau cauccaugcc cgccgaccuc cucauaaaag aacuagccaa cgucaacauc      240

cuagucaaac aaaucagcac ccccaaaggc cccucccucc gcguaaugau caacucccgc      300

uccgccgucc uagcccaaau gcccuccaaa uuuacaaucu gcgccaacgu cucccucgac      360

gaacgcucaa aacucgccua cgacgucacc acacccugcg aaaucaaagc cugcucccuc      420

accugccuca aaagcaaaaa uaugcuaacc accgucaaag accuuaccau gaaaacccuc      480

aaccccacuc acgacaucau agcccucugc gaauuugaaa acaucgucac cuccaaaaaa      540

gucaucaucc ccacauaccu ccgcuccauc uccguccgca acaaagaccu caacacccuc      600

gaaaacauca ccaccaccga auuuaaaaac gccaucacca acgccaaaau cauccccuac      660

uccggccucc uccucgucau caccguuacc gacaacaaag gcgccuucaa auacaucaaa      720

ccccaauccc aauucaucgu cgaccucgga gccuaccuug aaaaagaguc caucuacuac      780

gucaccacca acuggaaaca caccgccacc cgauucgcca ucaaacccau ggaagacuaa      840

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      900

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua      960

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1080

cccccccccc caaaggcucu uuucagagcc accagaauu                            1119


<210>  9941
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9941
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cgugaacaag cuucacgaag gcuccacaua cacagcugcu      120

guucaauaca augucuuaga aaaagacgau gacccugcau cacuuacaau augggugccc      180

auguuccaau caucuaugcc agcagauuua cuuauaaaag aacuagcuaa ugucaacaua      240

cuagugaaac aaauauccac acccaaggga ccuucacuaa gagucaugau aaacucaaga      300

agugcagugc uagcacaaau gcccagcaaa uuuaccauau gcgcuaaugu guccuuggau      360

gaaagaagca aacuagcaua ugauguaacc acacccugug aaaucaaggc auguagucua      420

acaugccuaa aaucaaaaaa uauguugacu acaguuaaag aucucacuau gaagacacuc      480

aacccuacac augauauuau ugcuuuaugu gaauuugaaa acauaguaac aucaaaaaaa      540

gucauaauac caacauaccu aagauccauc agugucagaa auaaagaucu gaacacacuu      600

gaaaauauaa caaccacuga auucaaaaau gcuaucacaa augcaaaaau caucccuuac      660

ucaggauuac uauuagucau cacagugacu gacaacaaag gagcauucaa auacauaaag      720

ccacaaaguc aauucauagu agaucuugga gcuuaccuag aaaaagaaag uauauauuau      780

guuaccacaa auuggaagca cacagcuaca cgauuugcaa ucaaacccau ggaagauuaa      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9942
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9942
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua cacggccgcc      120

guccaguaca acgugcucga gaaggacgac gaccccgcgu cccugaccau cugggugccg      180

auguuccaga gcuccaugcc cgccgaccug cucaucaagg agcuggccaa cgucaacauc      240

cuggugaagc agaucagcac ccccaagggg cccucccucc gcgugaugau caacagccgg      300

uccgccgucc uggcccagau gccgagcaag uucaccaucu gcgcgaacgu gucccuggac      360

gagcgcagca agcucgccua cgacgugacg acccccugcg agaucaaggc cugcucccug      420

accugccuca agagcaagaa caugcugacc acggucaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgugac guccaagaag      540

gugaucaucc ccaccuaccu gcggagcauc uccguccgca acaaggaccu gaacacccuc      600

gagaacauca ccacgaccga guucaagaac gcgaucacca acgccaagau caucccguac      660

agcggccugc ugcucgugau caccgugacg gacaacaagg gggccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacg cgguucgcga ucaagcccau ggaggacuga      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9943
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9943
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgucaacaag cuccacgagg gcuccaccua caccgccgcc      120

guccaguaca acguccucga gaaggacgac gaccccgccu cccucaccau cugggucccc      180

auguuccagu ccuccaugcc cgccgaccuc cucaucaagg agcucgccaa cgucaacauc      240

cucgucaagc agaucuccac ccccaagggc cccucccucc gcgucaugau caacucccgc      300

uccgccgucc ucgcccagau gcccuccaag uucaccaucu gcgccaacgu cucccucgac      360

gagcgcucca agcucgccua cgacgucacc acccccugcg agaucaaggc cugcucccuc      420

accugccuca aguccaagaa caugcucacc accgucaagg accucaccau gaagacccuc      480

aaccccaccc acgacaucau cgcccucugc gaguucgaga acaucgucac cuccaagaag      540

gucaucaucc ccaccuaccu ccgcuccauc uccguccgca acaaggaccu caacacccuc      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

uccggccucc uccucgucau caccgucacc gacaacaagg gcgccuucaa guacaucaag      720

ccccaguccc aguucaucgu cgaccucggc gccuaccucg agaaggaguc caucuacuac      780

gucaccacca acuggaagca caccgccacc cgcuucgcca ucaagcccau ggaggacuga      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9944
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9944
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacugccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgcau cccuuacgau cugggugccu      180

auguuccaau cuucaaugcc agccgaucug uugauuaagg aauuagcgaa cguaaauaua      240

cuggugaaac agaucaguac cccgaagggg cccagccuaa gagucaugau uaacuccagg      300

ucugcugugc ucgcccagau gccuucgaaa uuuacaaucu gcgcaaaugu uucacuggac      360

gagcggagca aacuugccua ugaugugacu accccaugug aaauuaaggc uugcagucug      420

acauguuuga aguccaagaa caugcucacc acugucaaag accugacaau gaagacccug      480

aaucccacgc augauaucau agcacucugc gaguucgaga acaucgugac uucuaaaaag      540

guaauuaucc cuaccuacuu acgcagcauu uccguucgaa auaaggaccu gaacacacuu      600

gaaaauauca cuaccacaga guuuaaaaac gccauaacca augcuaagau uaucccauau      660

ucaggauugc ugcuagugau uacggucacu gauaacaaag gugccuucaa guacaucaaa      720

ccccagaguc aauuuaucgu ggaccucggc gcguaucugg aaaaggagag cauuuacuac      780

gugacaacca auuggaaaca cacugcaaca cguuucgcca uaaagccuau ggaggauuga      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9945
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9945
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgagg gcagcaccua caccgccgcc      120

gugcaguaca acgugcugga gaaggacgac gaccccgcca gccugaccau cugggugccc      180

auguuccaga gcagcaugcc cgccgaccug cugaucaagg agcuggccaa cgugaacauc      240

cuggugaagc agaucagcac ccccaagggc cccagccuga gagugaugau caacagcaga      300

agcgccgugc uggcccagau gcccagcaag uucaccaucu gcgccaacgu gagccuggac      360

gagagaagca agcuggccua cgacgugacc acccccugcg agaucaaggc cugcagccug      420

accugccuga agagcaagaa caugcugacc accgugaagg accugaccau gaagacccug      480

aaccccaccc acgacaucau cgcccugugc gaguucgaga acaucgugac cagcaagaag      540

gugaucaucc ccaccuaccu gagaagcauc agcgugagaa acaaggaccu gaacacccug      600

gagaacauca ccaccaccga guucaagaac gccaucacca acgccaagau cauccccuac      660

agcggccugc ugcuggugau caccgugacc gacaacaagg gcgccuucaa guacaucaag      720

ccccagagcc aguucaucgu ggaccugggc gccuaccugg agaaggagag caucuacuac      780

gugaccacca acuggaagca caccgccacc agauucgcca ucaagcccau ggaggacuga      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9946
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9946
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaccua cgugaacaag cugcacgaag gcagcacaua uacggccgcu      120

guccaguaca auguucucga gaaagacgau gaccccgccu cccugaccau cugggugccu      180

auguuccaau cuagcaugcc ggcggaucuu cugauuaagg aacucgcuaa cgugaauauc      240

cuggucaaac agauuuccac acccaagggg ccuucucuua gagugaugau caacagccgg      300

uccgccguuc uggcccagau gcccucuaaa uuuaccauuu gcgcuaaugu gagccucgac      360

gagcgcucca agcuggccua ugaugucaca accccuugug aaaucaaggc uugcagccug      420

acaugucuca aaucuaagaa caugcugacc acggugaaag accuuaccau gaagacacug      480

aaucccaccc augauaucau ugcccucugc gaguucgaga acaucguuac auccaaaaag      540

gugauuaucc cuaccuaccu gagaagcauu ucuguccgga auaaggaccu uaacacgcug      600

gaaaauauca caaccacaga guuuaaaaac gcgauuacca augccaagau caucccguau      660

uccggacucc ugcuggugau uaccgugaca gauaacaaag gcgcuuucaa guacaucaaa      720

ccccagagcc aauuuauugu cgaccucggg gccuaucugg aaaaggaguc uaucuacuac      780

guuacgacca auuggaaaca cacagcuacc cgcuucgcca uuaagccuau ggaggauuga      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9947
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9947
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaacaua cguaaacaaa cuacacgaag gauccacaua cacagcagca      120

guacaauaca acguacuaga aaaagacgac gacccagcau cuuuaaccau auggguacca      180

auguuccaau caucaaugcc agcagaccuc uuaauaaaag aacuagcaaa cguaaacauc      240

cuagucaaac aaauaucaac acccaaagga ccaucccuca gaguaaugau caacucaaga      300

ucagcaguac uagcacaaau gccaucaaaa uucacaauau gcgccaacgu uucuuuagac      360

gaacgaucaa aauuagccua cgacguaaca acacccugcg aaauaaaagc augcucacua      420

acaugccuaa aaucaaaaaa caugcucacu acaguaaaag accuaaccau gaaaacacuc      480

aacccaacac acgacauaau agcccuaugc gaauuugaaa acauaguaac aucaaaaaaa      540

guaauaaucc caacauacuu aagaucgauc ucagucagaa acaaagaccu aaauacacuc      600

gaaaacauaa caacaacaga auuuaaaaac gcaauaacaa acgcaaaaau aauaccauac      660

ucaggacuac uccuaguaau aacaguaaca gacaacaaag gagcauucaa auacauaaaa      720

ccacaaucac aauucaucgu agaccucgga gcauaccuag aaaaagaauc aauauacuac      780

guaacaacaa acuggaaaca caccgccaca agauucgcaa uaaaacccau ggaagacuaa      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9948
<211>  1115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9948
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaccua cgucaacaaa cuacacgaag gcucaaccua caccgccgcc      120

guccaauaca acguccucga aaaagacgac gaccccgccu cccuaaccau cuggguuccc      180

auguuccaau cauccaugcc cgccgaccuc cucauaaaag aacuagccaa cgucaacauc      240

cuagucaaac aaaucagcac ccccaaaggc cccucccucc gcguaaugau caacucccgc      300

uccgccgucc uagcccaaau gcccuccaaa uuuacaaucu gcgccaacgu cucccucgac      360

gaacgcucaa aacucgccua cgacgucacc acacccugcg aaaucaaagc cugcucccuc      420

accugccuca aaagcaaaaa uaugcuaacc accgucaaag accuuaccau gaaaacccuc      480

aaccccacuc acgacaucau agcccucugc gaauuugaaa acaucgucac cuccaaaaaa      540

gucaucaucc ccacauaccu ccgcuccauc uccguccgca acaaagaccu caacacccuc      600

gaaaacauca ccaccaccga auuuaaaaac gccaucacca acgccaaaau cauccccuac      660

uccggccucc uccucgucau caccguuacc gacaacaaag gcgccuucaa auacaucaaa      720

ccccaauccc aauucaucgu cgaccucgga gccuaccuug aaaaagaguc caucuacuac      780

gucaccacca acuggaaaca caccgccacc cgauucgcca ucaaacccau ggaagacuaa      840

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      900

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua      960

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1080

cccccccaaa ggcucuuuuc agagccacca gaauu                                1115


<210>  9949
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9949
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu gaacaagcuu      120

cacgaaggcu ccacauacac agcugcuguu caauacaaug ucuuagaaaa agacgaugac      180

ccugcaucac uuacaauaug ggugcccaug uuccaaucau cuaugccagc agauuuacuu      240

auaaaagaac uagcuaaugu caacauacua gugaaacaaa uauccacacc caagggaccu      300

ucacuaagag ucaugauaaa cucaagaagu gcagugcuag cacaaaugcc cagcaaauuu      360

accauaugcg cuaauguguc cuuggaugaa agaagcaaac uagcauauga uguaaccaca      420

cccugugaaa ucaaggcaug uagucuaaca ugccuaaaau caaaaaauau guugacuaca      480

guuaaagauc ucacuaugaa gacacucaac ccuacacaug auauuauugc uuuaugugaa      540

uuugaaaaca uaguaacauc aaaaaaaguc auaauaccaa cauaccuaag auccaucagu      600

gucagaaaua aagaucugaa cacacuugaa aauauaacaa ccacugaauu caaaaaugcu      660

aucacaaaug caaaaaucau cccuuacuca ggauuacuau uagucaucac agugacugac      720

aacaaaggag cauucaaaua cauaaagcca caaagucaau ucauaguaga ucuuggagcu      780

uaccuagaaa aagaaaguau auauuauguu accacaaauu ggaagcacac agcuacacga      840

uuugcaauca aacccaugga agauuaagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9950
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9950
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac ggccgccguc caguacaacg ugcucgagaa ggacgacgac      180

cccgcguccc ugaccaucug ggugccgaug uuccagagcu ccaugcccgc cgaccugcuc      240

aucaaggagc uggccaacgu caacauccug gugaagcaga ucagcacccc caaggggccc      300

ucccuccgcg ugaugaucaa cagccggucc gccguccugg cccagaugcc gagcaaguuc      360

accaucugcg cgaacguguc ccuggacgag cgcagcaagc ucgccuacga cgugacgacc      420

cccugcgaga ucaaggccug cucccugacc ugccucaaga gcaagaacau gcugaccacg      480

gucaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgugacguc caagaaggug aucaucccca ccuaccugcg gagcaucucc      600

guccgcaaca aggaccugaa cacccucgag aacaucacca cgaccgaguu caagaacgcg      660

aucaccaacg ccaagaucau cccguacagc ggccugcugc ucgugaucac cgugacggac      720

aacaaggggg ccuucaagua caucaagccc cagucccagu ucaucgucga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccacgcgg      840

uucgcgauca agcccaugga ggacugagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9951
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9951
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu caacaagcuc      120

cacgagggcu ccaccuacac cgccgccguc caguacaacg uccucgagaa ggacgacgac      180

cccgccuccc ucaccaucug gguccccaug uuccaguccu ccaugcccgc cgaccuccuc      240

aucaaggagc ucgccaacgu caacauccuc gucaagcaga ucuccacccc caagggcccc      300

ucccuccgcg ucaugaucaa cucccgcucc gccguccucg cccagaugcc cuccaaguuc      360

accaucugcg ccaacgucuc ccucgacgag cgcuccaagc ucgccuacga cgucaccacc      420

cccugcgaga ucaaggccug cucccucacc ugccucaagu ccaagaacau gcucaccacc      480

gucaaggacc ucaccaugaa gacccucaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgucaccuc caagaagguc aucaucccca ccuaccuccg cuccaucucc      600

guccgcaaca aggaccucaa cacccucgag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacucc ggccuccucc ucgucaucac cgucaccgac      720

aacaagggcg ccuucaagua caucaagccc cagucccagu ucaucgucga ccucggcgcc      780

uaccucgaga aggaguccau cuacuacguc accaccaacu ggaagcacac cgccacccgc      840

uucgccauca agcccaugga ggacugagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9952
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9952
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ugccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgcauccc uuacgaucug ggugccuaug uuccaaucuu caaugccagc cgaucuguug      240

auuaaggaau uagcgaacgu aaauauacug gugaaacaga ucaguacccc gaaggggccc      300

agccuaagag ucaugauuaa cuccaggucu gcugugcucg cccagaugcc uucgaaauuu      360

acaaucugcg caaauguuuc acuggacgag cggagcaaac uugccuauga ugugacuacc      420

ccaugugaaa uuaaggcuug cagucugaca uguuugaagu ccaagaacau gcucaccacu      480

gucaaagacc ugacaaugaa gacccugaau cccacgcaug auaucauagc acucugcgag      540

uucgagaaca ucgugacuuc uaaaaaggua auuaucccua ccuacuuacg cagcauuucc      600

guucgaaaua aggaccugaa cacacuugaa aauaucacua ccacagaguu uaaaaacgcc      660

auaaccaaug cuaagauuau cccauauuca ggauugcugc uagugauuac ggucacugau      720

aacaaaggug ccuucaagua caucaaaccc cagagucaau uuaucgugga ccucggcgcg      780

uaucuggaaa aggagagcau uuacuacgug acaaccaauu ggaaacacac ugcaacacgu      840

uucgccauaa agccuaugga ggauugagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9953
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9953
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac cgccgccgug caguacaacg ugcuggagaa ggacgacgac      180

cccgccagcc ugaccaucug ggugcccaug uuccagagca gcaugcccgc cgaccugcug      240

aucaaggagc uggccaacgu gaacauccug gugaagcaga ucagcacccc caagggcccc      300

agccugagag ugaugaucaa cagcagaagc gccgugcugg cccagaugcc cagcaaguuc      360

accaucugcg ccaacgugag ccuggacgag agaagcaagc uggccuacga cgugaccacc      420

cccugcgaga ucaaggccug cagccugacc ugccugaaga gcaagaacau gcugaccacc      480

gugaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccugugcgag      540

uucgagaaca ucgugaccag caagaaggug aucaucccca ccuaccugag aagcaucagc      600

gugagaaaca aggaccugaa cacccuggag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacagc ggccugcugc uggugaucac cgugaccgac      720

aacaagggcg ccuucaagua caucaagccc cagagccagu ucaucgugga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccaccaga      840

uucgccauca agcccaugga ggacugagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9954
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9954
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ggccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgccuccc ugaccaucug ggugccuaug uuccaaucua gcaugccggc ggaucuucug      240

auuaaggaac ucgcuaacgu gaauauccug gucaaacaga uuuccacacc caaggggccu      300

ucucuuagag ugaugaucaa cagccggucc gccguucugg cccagaugcc cucuaaauuu      360

accauuugcg cuaaugugag ccucgacgag cgcuccaagc uggccuauga ugucacaacc      420

ccuugugaaa ucaaggcuug cagccugaca ugucucaaau cuaagaacau gcugaccacg      480

gugaaagacc uuaccaugaa gacacugaau cccacccaug auaucauugc ccucugcgag      540

uucgagaaca ucguuacauc caaaaaggug auuaucccua ccuaccugag aagcauuucu      600

guccggaaua aggaccuuaa cacgcuggaa aauaucacaa ccacagaguu uaaaaacgcg      660

auuaccaaug ccaagaucau cccguauucc ggacuccugc uggugauuac cgugacagau      720

aacaaaggcg cuuucaagua caucaaaccc cagagccaau uuauugucga ccucggggcc      780

uaucuggaaa aggagucuau cuacuacguu acgaccaauu ggaaacacac agcuacccgc      840

uucgccauua agccuaugga ggauugagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9955
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9955
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu aaacaaacua      120

cacgaaggau ccacauacac agcagcagua caauacaacg uacuagaaaa agacgacgac      180

ccagcaucuu uaaccauaug gguaccaaug uuccaaucau caaugccagc agaccucuua      240

auaaaagaac uagcaaacgu aaacauccua gucaaacaaa uaucaacacc caaaggacca      300

ucccucagag uaaugaucaa cucaagauca gcaguacuag cacaaaugcc aucaaaauuc      360

acaauaugcg ccaacguuuc uuuagacgaa cgaucaaaau uagccuacga cguaacaaca      420

cccugcgaaa uaaaagcaug cucacuaaca ugccuaaaau caaaaaacau gcucacuaca      480

guaaaagacc uaaccaugaa aacacucaac ccaacacacg acauaauagc ccuaugcgaa      540

uuugaaaaca uaguaacauc aaaaaaagua auaaucccaa cauacuuaag aucgaucuca      600

gucagaaaca aagaccuaaa uacacucgaa aacauaacaa caacagaauu uaaaaacgca      660

auaacaaacg caaaaauaau accauacuca ggacuacucc uaguaauaac aguaacagac      720

aacaaaggag cauucaaaua cauaaaacca caaucacaau ucaucguaga ccucggagca      780

uaccuagaaa aagaaucaau auacuacgua acaacaaacu ggaaacacac cgccacaaga      840

uucgcaauaa aacccaugga agacuaagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9956
<211>  1130
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9956
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaccuacgu caacaaacua      120

cacgaaggcu caaccuacac cgccgccguc caauacaacg uccucgaaaa agacgacgac      180

cccgccuccc uaaccaucug gguucccaug uuccaaucau ccaugcccgc cgaccuccuc      240

auaaaagaac uagccaacgu caacauccua gucaaacaaa ucagcacccc caaaggcccc      300

ucccuccgcg uaaugaucaa cucccgcucc gccguccuag cccaaaugcc cuccaaauuu      360

acaaucugcg ccaacgucuc ccucgacgaa cgcucaaaac ucgccuacga cgucaccaca      420

cccugcgaaa ucaaagccug cucccucacc ugccucaaaa gcaaaaauau gcuaaccacc      480

gucaaagacc uuaccaugaa aacccucaac cccacucacg acaucauagc ccucugcgaa      540

uuugaaaaca ucgucaccuc caaaaaaguc aucaucccca cauaccuccg cuccaucucc      600

guccgcaaca aagaccucaa cacccucgaa aacaucacca ccaccgaauu uaaaaacgcc      660

aucaccaacg ccaaaaucau ccccuacucc ggccuccucc ucgucaucac cguuaccgac      720

aacaaaggcg ccuucaaaua caucaaaccc caaucccaau ucaucgucga ccucggagcc      780

uaccuugaaa aagaguccau cuacuacguc accaccaacu ggaaacacac cgccacccga      840

uucgccauca aacccaugga agacuaagga cuaguaauaa ggaaacugua ugaaugucug      900

ugggcaggaa gugaagagau ccuucuguaa agguuuuugg aauuaugucu gcugaauaau      960

aaacuuuuuu gaaauaauaa aucugguaga aaaaugagau cuaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1080

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1130


<210>  9957
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9957
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu gaacaagcuu      120

cacgaaggcu ccacauacac agcugcuguu caauacaaug ucuuagaaaa agacgaugac      180

ccugcaucac uuacaauaug ggugcccaug uuccaaucau cuaugccagc agauuuacuu      240

auaaaagaac uagcuaaugu caacauacua gugaaacaaa uauccacacc caagggaccu      300

ucacuaagag ucaugauaaa cucaagaagu gcagugcuag cacaaaugcc cagcaaauuu      360

accauaugcg cuaauguguc cuuggaugaa agaagcaaac uagcauauga uguaaccaca      420

cccugugaaa ucaaggcaug uagucuaaca ugccuaaaau caaaaaauau guugacuaca      480

guuaaagauc ucacuaugaa gacacucaac ccuacacaug auauuauugc uuuaugugaa      540

uuugaaaaca uaguaacauc aaaaaaaguc auaauaccaa cauaccuaag auccaucagu      600

gucagaaaua aagaucugaa cacacuugaa aauauaacaa ccacugaauu caaaaaugcu      660

aucacaaaug caaaaaucau cccuuacuca ggauuacuau uagucaucac agugacugac      720

aacaaaggag cauucaaaua cauaaagcca caaagucaau ucauaguaga ucuuggagcu      780

uaccuagaaa aagaaaguau auauuauguu accacaaauu ggaagcacac agcuacacga      840

uuugcaauca aacccaugga agauuaagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9958
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9958
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac ggccgccguc caguacaacg ugcucgagaa ggacgacgac      180

cccgcguccc ugaccaucug ggugccgaug uuccagagcu ccaugcccgc cgaccugcuc      240

aucaaggagc uggccaacgu caacauccug gugaagcaga ucagcacccc caaggggccc      300

ucccuccgcg ugaugaucaa cagccggucc gccguccugg cccagaugcc gagcaaguuc      360

accaucugcg cgaacguguc ccuggacgag cgcagcaagc ucgccuacga cgugacgacc      420

cccugcgaga ucaaggccug cucccugacc ugccucaaga gcaagaacau gcugaccacg      480

gucaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgugacguc caagaaggug aucaucccca ccuaccugcg gagcaucucc      600

guccgcaaca aggaccugaa cacccucgag aacaucacca cgaccgaguu caagaacgcg      660

aucaccaacg ccaagaucau cccguacagc ggccugcugc ucgugaucac cgugacggac      720

aacaaggggg ccuucaagua caucaagccc cagucccagu ucaucgucga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccacgcgg      840

uucgcgauca agcccaugga ggacugagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9959
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9959
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu caacaagcuc      120

cacgagggcu ccaccuacac cgccgccguc caguacaacg uccucgagaa ggacgacgac      180

cccgccuccc ucaccaucug gguccccaug uuccaguccu ccaugcccgc cgaccuccuc      240

aucaaggagc ucgccaacgu caacauccuc gucaagcaga ucuccacccc caagggcccc      300

ucccuccgcg ucaugaucaa cucccgcucc gccguccucg cccagaugcc cuccaaguuc      360

accaucugcg ccaacgucuc ccucgacgag cgcuccaagc ucgccuacga cgucaccacc      420

cccugcgaga ucaaggccug cucccucacc ugccucaagu ccaagaacau gcucaccacc      480

gucaaggacc ucaccaugaa gacccucaac cccacccacg acaucaucgc ccucugcgag      540

uucgagaaca ucgucaccuc caagaagguc aucaucccca ccuaccuccg cuccaucucc      600

guccgcaaca aggaccucaa cacccucgag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacucc ggccuccucc ucgucaucac cgucaccgac      720

aacaagggcg ccuucaagua caucaagccc cagucccagu ucaucgucga ccucggcgcc      780

uaccucgaga aggaguccau cuacuacguc accaccaacu ggaagcacac cgccacccgc      840

uucgccauca agcccaugga ggacugagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9960
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9960
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ugccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgcauccc uuacgaucug ggugccuaug uuccaaucuu caaugccagc cgaucuguug      240

auuaaggaau uagcgaacgu aaauauacug gugaaacaga ucaguacccc gaaggggccc      300

agccuaagag ucaugauuaa cuccaggucu gcugugcucg cccagaugcc uucgaaauuu      360

acaaucugcg caaauguuuc acuggacgag cggagcaaac uugccuauga ugugacuacc      420

ccaugugaaa uuaaggcuug cagucugaca uguuugaagu ccaagaacau gcucaccacu      480

gucaaagacc ugacaaugaa gacccugaau cccacgcaug auaucauagc acucugcgag      540

uucgagaaca ucgugacuuc uaaaaaggua auuaucccua ccuacuuacg cagcauuucc      600

guucgaaaua aggaccugaa cacacuugaa aauaucacua ccacagaguu uaaaaacgcc      660

auaaccaaug cuaagauuau cccauauuca ggauugcugc uagugauuac ggucacugau      720

aacaaaggug ccuucaagua caucaaaccc cagagucaau uuaucgugga ccucggcgcg      780

uaucuggaaa aggagagcau uuacuacgug acaaccaauu ggaaacacac ugcaacacgu      840

uucgccauaa agccuaugga ggauugagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9961
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9961
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgagggca gcaccuacac cgccgccgug caguacaacg ugcuggagaa ggacgacgac      180

cccgccagcc ugaccaucug ggugcccaug uuccagagca gcaugcccgc cgaccugcug      240

aucaaggagc uggccaacgu gaacauccug gugaagcaga ucagcacccc caagggcccc      300

agccugagag ugaugaucaa cagcagaagc gccgugcugg cccagaugcc cagcaaguuc      360

accaucugcg ccaacgugag ccuggacgag agaagcaagc uggccuacga cgugaccacc      420

cccugcgaga ucaaggccug cagccugacc ugccugaaga gcaagaacau gcugaccacc      480

gugaaggacc ugaccaugaa gacccugaac cccacccacg acaucaucgc ccugugcgag      540

uucgagaaca ucgugaccag caagaaggug aucaucccca ccuaccugag aagcaucagc      600

gugagaaaca aggaccugaa cacccuggag aacaucacca ccaccgaguu caagaacgcc      660

aucaccaacg ccaagaucau ccccuacagc ggccugcugc uggugaucac cgugaccgac      720

aacaagggcg ccuucaagua caucaagccc cagagccagu ucaucgugga ccugggcgcc      780

uaccuggaga aggagagcau cuacuacgug accaccaacu ggaagcacac cgccaccaga      840

uucgccauca agcccaugga ggacugagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9962
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9962
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaccuacgu gaacaagcug      120

cacgaaggca gcacauauac ggccgcuguc caguacaaug uucucgagaa agacgaugac      180

cccgccuccc ugaccaucug ggugccuaug uuccaaucua gcaugccggc ggaucuucug      240

auuaaggaac ucgcuaacgu gaauauccug gucaaacaga uuuccacacc caaggggccu      300

ucucuuagag ugaugaucaa cagccggucc gccguucugg cccagaugcc cucuaaauuu      360

accauuugcg cuaaugugag ccucgacgag cgcuccaagc uggccuauga ugucacaacc      420

ccuugugaaa ucaaggcuug cagccugaca ugucucaaau cuaagaacau gcugaccacg      480

gugaaagacc uuaccaugaa gacacugaau cccacccaug auaucauugc ccucugcgag      540

uucgagaaca ucguuacauc caaaaaggug auuaucccua ccuaccugag aagcauuucu      600

guccggaaua aggaccuuaa cacgcuggaa aauaucacaa ccacagaguu uaaaaacgcg      660

auuaccaaug ccaagaucau cccguauucc ggacuccugc uggugauuac cgugacagau      720

aacaaaggcg cuuucaagua caucaaaccc cagagccaau uuauugucga ccucggggcc      780

uaucuggaaa aggagucuau cuacuacguu acgaccaauu ggaaacacac agcuacccgc      840

uucgccauua agccuaugga ggauugagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9963
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9963
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaacauacgu aaacaaacua      120

cacgaaggau ccacauacac agcagcagua caauacaacg uacuagaaaa agacgacgac      180

ccagcaucuu uaaccauaug gguaccaaug uuccaaucau caaugccagc agaccucuua      240

auaaaagaac uagcaaacgu aaacauccua gucaaacaaa uaucaacacc caaaggacca      300

ucccucagag uaaugaucaa cucaagauca gcaguacuag cacaaaugcc aucaaaauuc      360

acaauaugcg ccaacguuuc uuuagacgaa cgaucaaaau uagccuacga cguaacaaca      420

cccugcgaaa uaaaagcaug cucacuaaca ugccuaaaau caaaaaacau gcucacuaca      480

guaaaagacc uaaccaugaa aacacucaac ccaacacacg acauaauagc ccuaugcgaa      540

uuugaaaaca uaguaacauc aaaaaaagua auaaucccaa cauacuuaag aucgaucuca      600

gucagaaaca aagaccuaaa uacacucgaa aacauaacaa caacagaauu uaaaaacgca      660

auaacaaacg caaaaauaau accauacuca ggacuacucc uaguaauaac aguaacagac      720

aacaaaggag cauucaaaua cauaaaacca caaucacaau ucaucguaga ccucggagca      780

uaccuagaaa aagaaucaau auacuacgua acaacaaacu ggaaacacac cgccacaaga      840

uucgcaauaa aacccaugga agacuaagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9964
<211>  1362
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9964
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaccuacgu caacaaacua      120

cacgaaggcu caaccuacac cgccgccguc caauacaacg uccucgaaaa agacgacgac      180

cccgccuccc uaaccaucug gguucccaug uuccaaucau ccaugcccgc cgaccuccuc      240

auaaaagaac uagccaacgu caacauccua gucaaacaaa ucagcacccc caaaggcccc      300

ucccuccgcg uaaugaucaa cucccgcucc gccguccuag cccaaaugcc cuccaaauuu      360

acaaucugcg ccaacgucuc ccucgacgaa cgcucaaaac ucgccuacga cgucaccaca      420

cccugcgaaa ucaaagccug cucccucacc ugccucaaaa gcaaaaauau gcuaaccacc      480

gucaaagacc uuaccaugaa aacccucaac cccacucacg acaucauagc ccucugcgaa      540

uuugaaaaca ucgucaccuc caaaaaaguc aucaucccca cauaccuccg cuccaucucc      600

guccgcaaca aagaccucaa cacccucgaa aacaucacca ccaccgaauu uaaaaacgcc      660

aucaccaacg ccaaaaucau ccccuacucc ggccuccucc ucgucaucac cguuaccgac      720

aacaaaggcg ccuucaaaua caucaaaccc caaucccaau ucaucgucga ccucggagcc      780

uaccuugaaa aagaguccau cuacuacguc accaccaacu ggaaacacac cgccacccga      840

uucgccauca aacccaugga agacuaagga cuagugaagg gaacacccaa auuuaauuca      900

gccuuaagca caauuaauua agagugaaac guaauuguac aagcaguugg ucacccacca      960

uagggcauga ucaacaccgc aaccuuuccu uuuuccccca gugauucuga aaaaccccuc     1020

uucccuucag cuugcuuaga uguuccaaau uuaguaagcu uaaggcggcc uacagaagaa     1080

aaagaaaaaa aaggccacaa aaguucccuc ucacuuucag uaaauaaaau aaaagcagca     1140

acagaaauaa agaaauaaau gaaauucaaa augaaauaaa uauuguguug ugcagcauua     1200

aaaaaucaau aaaaauuaaa aaugagcaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1320

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1362


<210>  9965
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9965
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacgugaa caagcuucac gaaggcucca cauacacagc ugcuguucaa      180

uacaaugucu uagaaaaaga cgaugacccu gcaucacuua caauaugggu gcccauguuc      240

caaucaucua ugccagcaga uuuacuuaua aaagaacuag cuaaugucaa cauacuagug      300

aaacaaauau ccacacccaa gggaccuuca cuaagaguca ugauaaacuc aagaagugca      360

gugcuagcac aaaugcccag caaauuuacc auaugcgcua auguguccuu ggaugaaaga      420

agcaaacuag cauaugaugu aaccacaccc ugugaaauca aggcauguag ucuaacaugc      480

cuaaaaucaa aaaauauguu gacuacaguu aaagaucuca cuaugaagac acucaacccu      540

acacaugaua uuauugcuuu augugaauuu gaaaacauag uaacaucaaa aaaagucaua      600

auaccaacau accuaagauc caucaguguc agaaauaaag aucugaacac acuugaaaau      660

auaacaacca cugaauucaa aaaugcuauc acaaaugcaa aaaucauccc uuacucagga      720

uuacuauuag ucaucacagu gacugacaac aaaggagcau ucaaauacau aaagccacaa      780

agucaauuca uaguagaucu uggagcuuac cuagaaaaag aaaguauaua uuauguuacc      840

acaaauugga agcacacagc uacacgauuu gcaaucaaac ccauggaaga uuaaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9966
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9966
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacacggc cgccguccag      180

uacaacgugc ucgagaagga cgacgacccc gcgucccuga ccaucugggu gccgauguuc      240

cagagcucca ugcccgccga ccugcucauc aaggagcugg ccaacgucaa cauccuggug      300

aagcagauca gcacccccaa ggggcccucc cuccgcguga ugaucaacag ccgguccgcc      360

guccuggccc agaugccgag caaguucacc aucugcgcga acgugucccu ggacgagcgc      420

agcaagcucg ccuacgacgu gacgaccccc ugcgagauca aggccugcuc ccugaccugc      480

cucaagagca agaacaugcu gaccacgguc aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ugacguccaa gaaggugauc      600

auccccaccu accugcggag caucuccguc cgcaacaagg accugaacac ccucgagaac      660

aucaccacga ccgaguucaa gaacgcgauc accaacgcca agaucauccc guacagcggc      720

cugcugcucg ugaucaccgu gacggacaac aagggggccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc cacgcgguuc gcgaucaagc ccauggagga cugaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9967
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9967
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgucaa caagcuccac gagggcucca ccuacaccgc cgccguccag      180

uacaacgucc ucgagaagga cgacgacccc gccucccuca ccaucugggu ccccauguuc      240

caguccucca ugcccgccga ccuccucauc aaggagcucg ccaacgucaa cauccucguc      300

aagcagaucu ccacccccaa gggccccucc cuccgcguca ugaucaacuc ccgcuccgcc      360

guccucgccc agaugcccuc caaguucacc aucugcgcca acgucucccu cgacgagcgc      420

uccaagcucg ccuacgacgu caccaccccc ugcgagauca aggccugcuc ccucaccugc      480

cucaagucca agaacaugcu caccaccguc aaggaccuca ccaugaagac ccucaacccc      540

acccacgaca ucaucgcccu cugcgaguuc gagaacaucg ucaccuccaa gaaggucauc      600

auccccaccu accuccgcuc caucuccguc cgcaacaagg accucaacac ccucgagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu caccgacaac aagggcgccu ucaaguacau caagccccag      780

ucccaguuca ucgucgaccu cggcgccuac cucgagaagg aguccaucua cuacgucacc      840

accaacugga agcacaccgc cacccgcuuc gccaucaagc ccauggagga cugaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9968
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9968
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacugc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gcaucccuua cgaucugggu gccuauguuc      240

caaucuucaa ugccagccga ucuguugauu aaggaauuag cgaacguaaa uauacuggug      300

aaacagauca guaccccgaa ggggcccagc cuaagaguca ugauuaacuc caggucugcu      360

gugcucgccc agaugccuuc gaaauuuaca aucugcgcaa auguuucacu ggacgagcgg      420

agcaaacuug ccuaugaugu gacuacccca ugugaaauua aggcuugcag ucugacaugu      480

uugaagucca agaacaugcu caccacuguc aaagaccuga caaugaagac ccugaauccc      540

acgcaugaua ucauagcacu cugcgaguuc gagaacaucg ugacuucuaa aaagguaauu      600

aucccuaccu acuuacgcag cauuuccguu cgaaauaagg accugaacac acuugaaaau      660

aucacuacca cagaguuuaa aaacgccaua accaaugcua agauuauccc auauucagga      720

uugcugcuag ugauuacggu cacugauaac aaaggugccu ucaaguacau caaaccccag      780

agucaauuua ucguggaccu cggcgcguau cuggaaaagg agagcauuua cuacgugaca      840

accaauugga aacacacugc aacacguuuc gccauaaagc cuauggagga uugaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9969
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9969
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gagggcagca ccuacaccgc cgccgugcag      180

uacaacgugc uggagaagga cgacgacccc gccagccuga ccaucugggu gcccauguuc      240

cagagcagca ugcccgccga ccugcugauc aaggagcugg ccaacgugaa cauccuggug      300

aagcagauca gcacccccaa gggccccagc cugagaguga ugaucaacag cagaagcgcc      360

gugcuggccc agaugcccag caaguucacc aucugcgcca acgugagccu ggacgagaga      420

agcaagcugg ccuacgacgu gaccaccccc ugcgagauca aggccugcag ccugaccugc      480

cugaagagca agaacaugcu gaccaccgug aaggaccuga ccaugaagac ccugaacccc      540

acccacgaca ucaucgcccu gugcgaguuc gagaacaucg ugaccagcaa gaaggugauc      600

auccccaccu accugagaag caucagcgug agaaacaagg accugaacac ccuggagaac      660

aucaccacca ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacagcggc      720

cugcugcugg ugaucaccgu gaccgacaac aagggcgccu ucaaguacau caagccccag      780

agccaguuca ucguggaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc      840

accaacugga agcacaccgc caccagauuc gccaucaagc ccauggagga cugaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9970
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9970
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga ccuacgugaa caagcugcac gaaggcagca cauauacggc cgcuguccag      180

uacaauguuc ucgagaaaga cgaugacccc gccucccuga ccaucugggu gccuauguuc      240

caaucuagca ugccggcgga ucuucugauu aaggaacucg cuaacgugaa uauccugguc      300

aaacagauuu ccacacccaa ggggccuucu cuuagaguga ugaucaacag ccgguccgcc      360

guucuggccc agaugcccuc uaaauuuacc auuugcgcua augugagccu cgacgagcgc      420

uccaagcugg ccuaugaugu cacaaccccu ugugaaauca aggcuugcag ccugacaugu      480

cucaaaucua agaacaugcu gaccacggug aaagaccuua ccaugaagac acugaauccc      540

acccaugaua ucauugcccu cugcgaguuc gagaacaucg uuacauccaa aaaggugauu      600

aucccuaccu accugagaag cauuucuguc cggaauaagg accuuaacac gcuggaaaau      660

aucacaacca cagaguuuaa aaacgcgauu accaaugcca agaucauccc guauuccgga      720

cuccugcugg ugauuaccgu gacagauaac aaaggcgcuu ucaaguacau caaaccccag      780

agccaauuua uugucgaccu cggggccuau cuggaaaagg agucuaucua cuacguuacg      840

accaauugga aacacacagc uacccgcuuc gccauuaagc cuauggagga uugaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9971
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9971
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa cauacguaaa caaacuacac gaaggaucca cauacacagc agcaguacaa      180

uacaacguac uagaaaaaga cgacgaccca gcaucuuuaa ccauaugggu accaauguuc      240

caaucaucaa ugccagcaga ccucuuaaua aaagaacuag caaacguaaa cauccuaguc      300

aaacaaauau caacacccaa aggaccaucc cucagaguaa ugaucaacuc aagaucagca      360

guacuagcac aaaugccauc aaaauucaca auaugcgcca acguuucuuu agacgaacga      420

ucaaaauuag ccuacgacgu aacaacaccc ugcgaaauaa aagcaugcuc acuaacaugc      480

cuaaaaucaa aaaacaugcu cacuacagua aaagaccuaa ccaugaaaac acucaaccca      540

acacacgaca uaauagcccu augcgaauuu gaaaacauag uaacaucaaa aaaaguaaua      600

aucccaacau acuuaagauc gaucucaguc agaaacaaag accuaaauac acucgaaaac      660

auaacaacaa cagaauuuaa aaacgcaaua acaaacgcaa aaauaauacc auacucagga      720

cuacuccuag uaauaacagu aacagacaac aaaggagcau ucaaauacau aaaaccacaa      780

ucacaauuca ucguagaccu cggagcauac cuagaaaaag aaucaauaua cuacguaaca      840

acaaacugga aacacaccgc cacaagauuc gcaauaaaac ccauggaaga cuaaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9972
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9972
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa ccuacgucaa caaacuacac gaaggcucaa ccuacaccgc cgccguccaa      180

uacaacgucc ucgaaaaaga cgacgacccc gccucccuaa ccaucugggu ucccauguuc      240

caaucaucca ugcccgccga ccuccucaua aaagaacuag ccaacgucaa cauccuaguc      300

aaacaaauca gcacccccaa aggccccucc cuccgcguaa ugaucaacuc ccgcuccgcc      360

guccuagccc aaaugcccuc caaauuuaca aucugcgcca acgucucccu cgacgaacgc      420

ucaaaacucg ccuacgacgu caccacaccc ugcgaaauca aagccugcuc ccucaccugc      480

cucaaaagca aaaauaugcu aaccaccguc aaagaccuua ccaugaaaac ccucaacccc      540

acucacgaca ucauagcccu cugcgaauuu gaaaacaucg ucaccuccaa aaaagucauc      600

auccccacau accuccgcuc caucuccguc cgcaacaaag accucaacac ccucgaaaac      660

aucaccacca ccgaauuuaa aaacgccauc accaacgcca aaaucauccc cuacuccggc      720

cuccuccucg ucaucaccgu uaccgacaac aaaggcgccu ucaaauacau caaaccccaa      780

ucccaauuca ucgucgaccu cggagccuac cuugaaaaag aguccaucua cuacgucacc      840

accaacugga aacacaccgc cacccgauuc gccaucaaac ccauggaaga cuaaggacua      900

guaauaagga aacuguauga augucugugg gcaggaagug aagagauccu ucuguaaagg      960

uuuuuggaau uaugucugcu gaauaauaaa cuuuuuugaa auaauaaauc ugguagaaaa     1020

augagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  9973
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9973
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cgugaacaag      120

cuucacgaag gcuccacaua cacagcugcu guucaauaca augucuuaga aaaagacgau      180

gacccugcau cacuuacaau augggugccc auguuccaau caucuaugcc agcagauuua      240

cuuauaaaag aacuagcuaa ugucaacaua cuagugaaac aaauauccac acccaaggga      300

ccuucacuaa gagucaugau aaacucaaga agugcagugc uagcacaaau gcccagcaaa      360

uuuaccauau gcgcuaaugu guccuuggau gaaagaagca aacuagcaua ugauguaacc      420

acacccugug aaaucaaggc auguagucua acaugccuaa aaucaaaaaa uauguugacu      480

acaguuaaag aucucacuau gaagacacuc aacccuacac augauauuau ugcuuuaugu      540

gaauuugaaa acauaguaac aucaaaaaaa gucauaauac caacauaccu aagauccauc      600

agugucagaa auaaagaucu gaacacacuu gaaaauauaa caaccacuga auucaaaaau      660

gcuaucacaa augcaaaaau caucccuuac ucaggauuac uauuagucau cacagugacu      720

gacaacaaag gagcauucaa auacauaaag ccacaaaguc aauucauagu agaucuugga      780

gcuuaccuag aaaaagaaag uauauauuau guuaccacaa auuggaagca cacagcuaca      840

cgauuugcaa ucaaacccau ggaagauuaa ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9974
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9974
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua cacggccgcc guccaguaca acgugcucga gaaggacgac      180

gaccccgcgu cccugaccau cugggugccg auguuccaga gcuccaugcc cgccgaccug      240

cucaucaagg agcuggccaa cgucaacauc cuggugaagc agaucagcac ccccaagggg      300

cccucccucc gcgugaugau caacagccgg uccgccgucc uggcccagau gccgagcaag      360

uucaccaucu gcgcgaacgu gucccuggac gagcgcagca agcucgccua cgacgugacg      420

acccccugcg agaucaaggc cugcucccug accugccuca agagcaagaa caugcugacc      480

acggucaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgugac guccaagaag gugaucaucc ccaccuaccu gcggagcauc      600

uccguccgca acaaggaccu gaacacccuc gagaacauca ccacgaccga guucaagaac      660

gcgaucacca acgccaagau caucccguac agcggccugc ugcucgugau caccgugacg      720

gacaacaagg gggccuucaa guacaucaag ccccaguccc aguucaucgu cgaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacg      840

cgguucgcga ucaagcccau ggaggacuga ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9975
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9975
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgucaacaag      120

cuccacgagg gcuccaccua caccgccgcc guccaguaca acguccucga gaaggacgac      180

gaccccgccu cccucaccau cugggucccc auguuccagu ccuccaugcc cgccgaccuc      240

cucaucaagg agcucgccaa cgucaacauc cucgucaagc agaucuccac ccccaagggc      300

cccucccucc gcgucaugau caacucccgc uccgccgucc ucgcccagau gcccuccaag      360

uucaccaucu gcgccaacgu cucccucgac gagcgcucca agcucgccua cgacgucacc      420

acccccugcg agaucaaggc cugcucccuc accugccuca aguccaagaa caugcucacc      480

accgucaagg accucaccau gaagacccuc aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgucac cuccaagaag gucaucaucc ccaccuaccu ccgcuccauc      600

uccguccgca acaaggaccu caacacccuc gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac uccggccucc uccucgucau caccgucacc      720

gacaacaagg gcgccuucaa guacaucaag ccccaguccc aguucaucgu cgaccucggc      780

gccuaccucg agaaggaguc caucuacuac gucaccacca acuggaagca caccgccacc      840

cgcuucgcca ucaagcccau ggaggacuga ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9976
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9976
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacugccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgcau cccuuacgau cugggugccu auguuccaau cuucaaugcc agccgaucug      240

uugauuaagg aauuagcgaa cguaaauaua cuggugaaac agaucaguac cccgaagggg      300

cccagccuaa gagucaugau uaacuccagg ucugcugugc ucgcccagau gccuucgaaa      360

uuuacaaucu gcgcaaaugu uucacuggac gagcggagca aacuugccua ugaugugacu      420

accccaugug aaauuaaggc uugcagucug acauguuuga aguccaagaa caugcucacc      480

acugucaaag accugacaau gaagacccug aaucccacgc augauaucau agcacucugc      540

gaguucgaga acaucgugac uucuaaaaag guaauuaucc cuaccuacuu acgcagcauu      600

uccguucgaa auaaggaccu gaacacacuu gaaaauauca cuaccacaga guuuaaaaac      660

gccauaacca augcuaagau uaucccauau ucaggauugc ugcuagugau uacggucacu      720

gauaacaaag gugccuucaa guacaucaaa ccccagaguc aauuuaucgu ggaccucggc      780

gcguaucugg aaaaggagag cauuuacuac gugacaacca auuggaaaca cacugcaaca      840

cguuucgcca uaaagccuau ggaggauuga ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9977
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9977
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua caccgccgcc gugcaguaca acgugcugga gaaggacgac      180

gaccccgcca gccugaccau cugggugccc auguuccaga gcagcaugcc cgccgaccug      240

cugaucaagg agcuggccaa cgugaacauc cuggugaagc agaucagcac ccccaagggc      300

cccagccuga gagugaugau caacagcaga agcgccgugc uggcccagau gcccagcaag      360

uucaccaucu gcgccaacgu gagccuggac gagagaagca agcuggccua cgacgugacc      420

acccccugcg agaucaaggc cugcagccug accugccuga agagcaagaa caugcugacc      480

accgugaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccugugc      540

gaguucgaga acaucgugac cagcaagaag gugaucaucc ccaccuaccu gagaagcauc      600

agcgugagaa acaaggaccu gaacacccug gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac agcggccugc ugcuggugau caccgugacc      720

gacaacaagg gcgccuucaa guacaucaag ccccagagcc aguucaucgu ggaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacc      840

agauucgcca ucaagcccau ggaggacuga ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9978
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9978
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacggccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgccu cccugaccau cugggugccu auguuccaau cuagcaugcc ggcggaucuu      240

cugauuaagg aacucgcuaa cgugaauauc cuggucaaac agauuuccac acccaagggg      300

ccuucucuua gagugaugau caacagccgg uccgccguuc uggcccagau gcccucuaaa      360

uuuaccauuu gcgcuaaugu gagccucgac gagcgcucca agcuggccua ugaugucaca      420

accccuugug aaaucaaggc uugcagccug acaugucuca aaucuaagaa caugcugacc      480

acggugaaag accuuaccau gaagacacug aaucccaccc augauaucau ugcccucugc      540

gaguucgaga acaucguuac auccaaaaag gugauuaucc cuaccuaccu gagaagcauu      600

ucuguccgga auaaggaccu uaacacgcug gaaaauauca caaccacaga guuuaaaaac      660

gcgauuacca augccaagau caucccguau uccggacucc ugcuggugau uaccgugaca      720

gauaacaaag gcgcuuucaa guacaucaaa ccccagagcc aauuuauugu cgaccucggg      780

gccuaucugg aaaaggaguc uaucuacuac guuacgacca auuggaaaca cacagcuacc      840

cgcuucgcca uuaagccuau ggaggauuga ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9979
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9979
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cguaaacaaa      120

cuacacgaag gauccacaua cacagcagca guacaauaca acguacuaga aaaagacgac      180

gacccagcau cuuuaaccau auggguacca auguuccaau caucaaugcc agcagaccuc      240

uuaauaaaag aacuagcaaa cguaaacauc cuagucaaac aaauaucaac acccaaagga      300

ccaucccuca gaguaaugau caacucaaga ucagcaguac uagcacaaau gccaucaaaa      360

uucacaauau gcgccaacgu uucuuuagac gaacgaucaa aauuagccua cgacguaaca      420

acacccugcg aaauaaaagc augcucacua acaugccuaa aaucaaaaaa caugcucacu      480

acaguaaaag accuaaccau gaaaacacuc aacccaacac acgacauaau agcccuaugc      540

gaauuugaaa acauaguaac aucaaaaaaa guaauaaucc caacauacuu aagaucgauc      600

ucagucagaa acaaagaccu aaauacacuc gaaaacauaa caacaacaga auuuaaaaac      660

gcaauaacaa acgcaaaaau aauaccauac ucaggacuac uccuaguaau aacaguaaca      720

gacaacaaag gagcauucaa auacauaaaa ccacaaucac aauucaucgu agaccucgga      780

gcauaccuag aaaaagaauc aauauacuac guaacaacaa acuggaaaca caccgccaca      840

agauucgcaa uaaaacccau ggaagacuaa ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9980
<211>  1133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9980
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaccua cgucaacaaa      120

cuacacgaag gcucaaccua caccgccgcc guccaauaca acguccucga aaaagacgac      180

gaccccgccu cccuaaccau cuggguuccc auguuccaau cauccaugcc cgccgaccuc      240

cucauaaaag aacuagccaa cgucaacauc cuagucaaac aaaucagcac ccccaaaggc      300

cccucccucc gcguaaugau caacucccgc uccgccgucc uagcccaaau gcccuccaaa      360

uuuacaaucu gcgccaacgu cucccucgac gaacgcucaa aacucgccua cgacgucacc      420

acacccugcg aaaucaaagc cugcucccuc accugccuca aaagcaaaaa uaugcuaacc      480

accgucaaag accuuaccau gaaaacccuc aaccccacuc acgacaucau agcccucugc      540

gaauuugaaa acaucgucac cuccaaaaaa gucaucaucc ccacauaccu ccgcuccauc      600

uccguccgca acaaagaccu caacacccuc gaaaacauca ccaccaccga auuuaaaaac      660

gccaucacca acgccaaaau cauccccuac uccggccucc uccucgucau caccguuacc      720

gacaacaaag gcgccuucaa auacaucaaa ccccaauccc aauucaucgu cgaccucgga      780

gccuaccuug aaaaagaguc caucuacuac gucaccacca acuggaaaca caccgccacc      840

cgauucgcca ucaaacccau ggaagacuaa ggacuaguaa uaaggaaacu guaugaaugu      900

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau      960

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1080

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1133


<210>  9981
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9981
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cgugaacaag      120

cuucacgaag gcuccacaua cacagcugcu guucaauaca augucuuaga aaaagacgau      180

gacccugcau cacuuacaau augggugccc auguuccaau caucuaugcc agcagauuua      240

cuuauaaaag aacuagcuaa ugucaacaua cuagugaaac aaauauccac acccaaggga      300

ccuucacuaa gagucaugau aaacucaaga agugcagugc uagcacaaau gcccagcaaa      360

uuuaccauau gcgcuaaugu guccuuggau gaaagaagca aacuagcaua ugauguaacc      420

acacccugug aaaucaaggc auguagucua acaugccuaa aaucaaaaaa uauguugacu      480

acaguuaaag aucucacuau gaagacacuc aacccuacac augauauuau ugcuuuaugu      540

gaauuugaaa acauaguaac aucaaaaaaa gucauaauac caacauaccu aagauccauc      600

agugucagaa auaaagaucu gaacacacuu gaaaauauaa caaccacuga auucaaaaau      660

gcuaucacaa augcaaaaau caucccuuac ucaggauuac uauuagucau cacagugacu      720

gacaacaaag gagcauucaa auacauaaag ccacaaaguc aauucauagu agaucuugga      780

gcuuaccuag aaaaagaaag uauauauuau guuaccacaa auuggaagca cacagcuaca      840

cgauuugcaa ucaaacccau ggaagauuaa ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9982
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9982
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua cacggccgcc guccaguaca acgugcucga gaaggacgac      180

gaccccgcgu cccugaccau cugggugccg auguuccaga gcuccaugcc cgccgaccug      240

cucaucaagg agcuggccaa cgucaacauc cuggugaagc agaucagcac ccccaagggg      300

cccucccucc gcgugaugau caacagccgg uccgccgucc uggcccagau gccgagcaag      360

uucaccaucu gcgcgaacgu gucccuggac gagcgcagca agcucgccua cgacgugacg      420

acccccugcg agaucaaggc cugcucccug accugccuca agagcaagaa caugcugacc      480

acggucaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgugac guccaagaag gugaucaucc ccaccuaccu gcggagcauc      600

uccguccgca acaaggaccu gaacacccuc gagaacauca ccacgaccga guucaagaac      660

gcgaucacca acgccaagau caucccguac agcggccugc ugcucgugau caccgugacg      720

gacaacaagg gggccuucaa guacaucaag ccccaguccc aguucaucgu cgaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacg      840

cgguucgcga ucaagcccau ggaggacuga ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9983
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9983
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgucaacaag      120

cuccacgagg gcuccaccua caccgccgcc guccaguaca acguccucga gaaggacgac      180

gaccccgccu cccucaccau cugggucccc auguuccagu ccuccaugcc cgccgaccuc      240

cucaucaagg agcucgccaa cgucaacauc cucgucaagc agaucuccac ccccaagggc      300

cccucccucc gcgucaugau caacucccgc uccgccgucc ucgcccagau gcccuccaag      360

uucaccaucu gcgccaacgu cucccucgac gagcgcucca agcucgccua cgacgucacc      420

acccccugcg agaucaaggc cugcucccuc accugccuca aguccaagaa caugcucacc      480

accgucaagg accucaccau gaagacccuc aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgucac cuccaagaag gucaucaucc ccaccuaccu ccgcuccauc      600

uccguccgca acaaggaccu caacacccuc gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac uccggccucc uccucgucau caccgucacc      720

gacaacaagg gcgccuucaa guacaucaag ccccaguccc aguucaucgu cgaccucggc      780

gccuaccucg agaaggaguc caucuacuac gucaccacca acuggaagca caccgccacc      840

cgcuucgcca ucaagcccau ggaggacuga ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9984
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9984
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacugccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgcau cccuuacgau cugggugccu auguuccaau cuucaaugcc agccgaucug      240

uugauuaagg aauuagcgaa cguaaauaua cuggugaaac agaucaguac cccgaagggg      300

cccagccuaa gagucaugau uaacuccagg ucugcugugc ucgcccagau gccuucgaaa      360

uuuacaaucu gcgcaaaugu uucacuggac gagcggagca aacuugccua ugaugugacu      420

accccaugug aaauuaaggc uugcagucug acauguuuga aguccaagaa caugcucacc      480

acugucaaag accugacaau gaagacccug aaucccacgc augauaucau agcacucugc      540

gaguucgaga acaucgugac uucuaaaaag guaauuaucc cuaccuacuu acgcagcauu      600

uccguucgaa auaaggaccu gaacacacuu gaaaauauca cuaccacaga guuuaaaaac      660

gccauaacca augcuaagau uaucccauau ucaggauugc ugcuagugau uacggucacu      720

gauaacaaag gugccuucaa guacaucaaa ccccagaguc aauuuaucgu ggaccucggc      780

gcguaucugg aaaaggagag cauuuacuac gugacaacca auuggaaaca cacugcaaca      840

cguuucgcca uaaagccuau ggaggauuga ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9985
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9985
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua caccgccgcc gugcaguaca acgugcugga gaaggacgac      180

gaccccgcca gccugaccau cugggugccc auguuccaga gcagcaugcc cgccgaccug      240

cugaucaagg agcuggccaa cgugaacauc cuggugaagc agaucagcac ccccaagggc      300

cccagccuga gagugaugau caacagcaga agcgccgugc uggcccagau gcccagcaag      360

uucaccaucu gcgccaacgu gagccuggac gagagaagca agcuggccua cgacgugacc      420

acccccugcg agaucaaggc cugcagccug accugccuga agagcaagaa caugcugacc      480

accgugaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccugugc      540

gaguucgaga acaucgugac cagcaagaag gugaucaucc ccaccuaccu gagaagcauc      600

agcgugagaa acaaggaccu gaacacccug gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac agcggccugc ugcuggugau caccgugacc      720

gacaacaagg gcgccuucaa guacaucaag ccccagagcc aguucaucgu ggaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacc      840

agauucgcca ucaagcccau ggaggacuga ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9986
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9986
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacggccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgccu cccugaccau cugggugccu auguuccaau cuagcaugcc ggcggaucuu      240

cugauuaagg aacucgcuaa cgugaauauc cuggucaaac agauuuccac acccaagggg      300

ccuucucuua gagugaugau caacagccgg uccgccguuc uggcccagau gcccucuaaa      360

uuuaccauuu gcgcuaaugu gagccucgac gagcgcucca agcuggccua ugaugucaca      420

accccuugug aaaucaaggc uugcagccug acaugucuca aaucuaagaa caugcugacc      480

acggugaaag accuuaccau gaagacacug aaucccaccc augauaucau ugcccucugc      540

gaguucgaga acaucguuac auccaaaaag gugauuaucc cuaccuaccu gagaagcauu      600

ucuguccgga auaaggaccu uaacacgcug gaaaauauca caaccacaga guuuaaaaac      660

gcgauuacca augccaagau caucccguau uccggacucc ugcuggugau uaccgugaca      720

gauaacaaag gcgcuuucaa guacaucaaa ccccagagcc aauuuauugu cgaccucggg      780

gccuaucugg aaaaggaguc uaucuacuac guuacgacca auuggaaaca cacagcuacc      840

cgcuucgcca uuaagccuau ggaggauuga ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9987
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9987
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cguaaacaaa      120

cuacacgaag gauccacaua cacagcagca guacaauaca acguacuaga aaaagacgac      180

gacccagcau cuuuaaccau auggguacca auguuccaau caucaaugcc agcagaccuc      240

uuaauaaaag aacuagcaaa cguaaacauc cuagucaaac aaauaucaac acccaaagga      300

ccaucccuca gaguaaugau caacucaaga ucagcaguac uagcacaaau gccaucaaaa      360

uucacaauau gcgccaacgu uucuuuagac gaacgaucaa aauuagccua cgacguaaca      420

acacccugcg aaauaaaagc augcucacua acaugccuaa aaucaaaaaa caugcucacu      480

acaguaaaag accuaaccau gaaaacacuc aacccaacac acgacauaau agcccuaugc      540

gaauuugaaa acauaguaac aucaaaaaaa guaauaaucc caacauacuu aagaucgauc      600

ucagucagaa acaaagaccu aaauacacuc gaaaacauaa caacaacaga auuuaaaaac      660

gcaauaacaa acgcaaaaau aauaccauac ucaggacuac uccuaguaau aacaguaaca      720

gacaacaaag gagcauucaa auacauaaaa ccacaaucac aauucaucgu agaccucgga      780

gcauaccuag aaaaagaauc aauauacuac guaacaacaa acuggaaaca caccgccaca      840

agauucgcaa uaaaacccau ggaagacuaa ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9988
<211>  1149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9988
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaccua cgucaacaaa      120

cuacacgaag gcucaaccua caccgccgcc guccaauaca acguccucga aaaagacgac      180

gaccccgccu cccuaaccau cuggguuccc auguuccaau cauccaugcc cgccgaccuc      240

cucauaaaag aacuagccaa cgucaacauc cuagucaaac aaaucagcac ccccaaaggc      300

cccucccucc gcguaaugau caacucccgc uccgccgucc uagcccaaau gcccuccaaa      360

uuuacaaucu gcgccaacgu cucccucgac gaacgcucaa aacucgccua cgacgucacc      420

acacccugcg aaaucaaagc cugcucccuc accugccuca aaagcaaaaa uaugcuaacc      480

accgucaaag accuuaccau gaaaacccuc aaccccacuc acgacaucau agcccucugc      540

gaauuugaaa acaucgucac cuccaaaaaa gucaucaucc ccacauaccu ccgcuccauc      600

uccguccgca acaaagaccu caacacccuc gaaaacauca ccaccaccga auuuaaaaac      660

gccaucacca acgccaaaau cauccccuac uccggccucc uccucgucau caccguuacc      720

gacaacaaag gcgccuucaa auacaucaaa ccccaauccc aauucaucgu cgaccucgga      780

gccuaccuug aaaaagaguc caucuacuac gucaccacca acuggaaaca caccgccacc      840

cgauucgcca ucaaacccau ggaagacuaa ggacuaguac uggcugcauc ucccuuuccu      900

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc      960

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1020

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1140

accagaauu                                                             1149


<210>  9989
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9989
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cgugaacaag      120

cuucacgaag gcuccacaua cacagcugcu guucaauaca augucuuaga aaaagacgau      180

gacccugcau cacuuacaau augggugccc auguuccaau caucuaugcc agcagauuua      240

cuuauaaaag aacuagcuaa ugucaacaua cuagugaaac aaauauccac acccaaggga      300

ccuucacuaa gagucaugau aaacucaaga agugcagugc uagcacaaau gcccagcaaa      360

uuuaccauau gcgcuaaugu guccuuggau gaaagaagca aacuagcaua ugauguaacc      420

acacccugug aaaucaaggc auguagucua acaugccuaa aaucaaaaaa uauguugacu      480

acaguuaaag aucucacuau gaagacacuc aacccuacac augauauuau ugcuuuaugu      540

gaauuugaaa acauaguaac aucaaaaaaa gucauaauac caacauaccu aagauccauc      600

agugucagaa auaaagaucu gaacacacuu gaaaauauaa caaccacuga auucaaaaau      660

gcuaucacaa augcaaaaau caucccuuac ucaggauuac uauuagucau cacagugacu      720

gacaacaaag gagcauucaa auacauaaag ccacaaaguc aauucauagu agaucuugga      780

gcuuaccuag aaaaagaaag uauauauuau guuaccacaa auuggaagca cacagcuaca      840

cgauuugcaa ucaaacccau ggaagauuaa ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9990
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9990
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua cacggccgcc guccaguaca acgugcucga gaaggacgac      180

gaccccgcgu cccugaccau cugggugccg auguuccaga gcuccaugcc cgccgaccug      240

cucaucaagg agcuggccaa cgucaacauc cuggugaagc agaucagcac ccccaagggg      300

cccucccucc gcgugaugau caacagccgg uccgccgucc uggcccagau gccgagcaag      360

uucaccaucu gcgcgaacgu gucccuggac gagcgcagca agcucgccua cgacgugacg      420

acccccugcg agaucaaggc cugcucccug accugccuca agagcaagaa caugcugacc      480

acggucaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgugac guccaagaag gugaucaucc ccaccuaccu gcggagcauc      600

uccguccgca acaaggaccu gaacacccuc gagaacauca ccacgaccga guucaagaac      660

gcgaucacca acgccaagau caucccguac agcggccugc ugcucgugau caccgugacg      720

gacaacaagg gggccuucaa guacaucaag ccccaguccc aguucaucgu cgaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacg      840

cgguucgcga ucaagcccau ggaggacuga ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9991
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9991
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgucaacaag      120

cuccacgagg gcuccaccua caccgccgcc guccaguaca acguccucga gaaggacgac      180

gaccccgccu cccucaccau cugggucccc auguuccagu ccuccaugcc cgccgaccuc      240

cucaucaagg agcucgccaa cgucaacauc cucgucaagc agaucuccac ccccaagggc      300

cccucccucc gcgucaugau caacucccgc uccgccgucc ucgcccagau gcccuccaag      360

uucaccaucu gcgccaacgu cucccucgac gagcgcucca agcucgccua cgacgucacc      420

acccccugcg agaucaaggc cugcucccuc accugccuca aguccaagaa caugcucacc      480

accgucaagg accucaccau gaagacccuc aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgucac cuccaagaag gucaucaucc ccaccuaccu ccgcuccauc      600

uccguccgca acaaggaccu caacacccuc gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac uccggccucc uccucgucau caccgucacc      720

gacaacaagg gcgccuucaa guacaucaag ccccaguccc aguucaucgu cgaccucggc      780

gccuaccucg agaaggaguc caucuacuac gucaccacca acuggaagca caccgccacc      840

cgcuucgcca ucaagcccau ggaggacuga ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9992
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  9992
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacugccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgcau cccuuacgau cugggugccu auguuccaau cuucaaugcc agccgaucug      240

uugauuaagg aauuagcgaa cguaaauaua cuggugaaac agaucaguac cccgaagggg      300

cccagccuaa gagucaugau uaacuccagg ucugcugugc ucgcccagau gccuucgaaa      360

uuuacaaucu gcgcaaaugu uucacuggac gagcggagca aacuugccua ugaugugacu      420

accccaugug aaauuaaggc uugcagucug acauguuuga aguccaagaa caugcucacc      480

acugucaaag accugacaau gaagacccug aaucccacgc augauaucau agcacucugc      540

gaguucgaga acaucgugac uucuaaaaag guaauuaucc cuaccuacuu acgcagcauu      600

uccguucgaa auaaggaccu gaacacacuu gaaaauauca cuaccacaga guuuaaaaac      660

gccauaacca augcuaagau uaucccauau ucaggauugc ugcuagugau uacggucacu      720

gauaacaaag gugccuucaa guacaucaaa ccccagaguc aauuuaucgu ggaccucggc      780

gcguaucugg aaaaggagag cauuuacuac gugacaacca auuggaaaca cacugcaaca      840

cguuucgcca uaaagccuau ggaggauuga ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9993
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  9993
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua caccgccgcc gugcaguaca acgugcugga gaaggacgac      180

gaccccgcca gccugaccau cugggugccc auguuccaga gcagcaugcc cgccgaccug      240

cugaucaagg agcuggccaa cgugaacauc cuggugaagc agaucagcac ccccaagggc      300

cccagccuga gagugaugau caacagcaga agcgccgugc uggcccagau gcccagcaag      360

uucaccaucu gcgccaacgu gagccuggac gagagaagca agcuggccua cgacgugacc      420

acccccugcg agaucaaggc cugcagccug accugccuga agagcaagaa caugcugacc      480

accgugaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccugugc      540

gaguucgaga acaucgugac cagcaagaag gugaucaucc ccaccuaccu gagaagcauc      600

agcgugagaa acaaggaccu gaacacccug gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac agcggccugc ugcuggugau caccgugacc      720

gacaacaagg gcgccuucaa guacaucaag ccccagagcc aguucaucgu ggaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacc      840

agauucgcca ucaagcccau ggaggacuga ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9994
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  9994
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacggccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgccu cccugaccau cugggugccu auguuccaau cuagcaugcc ggcggaucuu      240

cugauuaagg aacucgcuaa cgugaauauc cuggucaaac agauuuccac acccaagggg      300

ccuucucuua gagugaugau caacagccgg uccgccguuc uggcccagau gcccucuaaa      360

uuuaccauuu gcgcuaaugu gagccucgac gagcgcucca agcuggccua ugaugucaca      420

accccuugug aaaucaaggc uugcagccug acaugucuca aaucuaagaa caugcugacc      480

acggugaaag accuuaccau gaagacacug aaucccaccc augauaucau ugcccucugc      540

gaguucgaga acaucguuac auccaaaaag gugauuaucc cuaccuaccu gagaagcauu      600

ucuguccgga auaaggaccu uaacacgcug gaaaauauca caaccacaga guuuaaaaac      660

gcgauuacca augccaagau caucccguau uccggacucc ugcuggugau uaccgugaca      720

gauaacaaag gcgcuuucaa guacaucaaa ccccagagcc aauuuauugu cgaccucggg      780

gccuaucugg aaaaggaguc uaucuacuac guuacgacca auuggaaaca cacagcuacc      840

cgcuucgcca uuaagccuau ggaggauuga ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9995
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  9995
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cguaaacaaa      120

cuacacgaag gauccacaua cacagcagca guacaauaca acguacuaga aaaagacgac      180

gacccagcau cuuuaaccau auggguacca auguuccaau caucaaugcc agcagaccuc      240

uuaauaaaag aacuagcaaa cguaaacauc cuagucaaac aaauaucaac acccaaagga      300

ccaucccuca gaguaaugau caacucaaga ucagcaguac uagcacaaau gccaucaaaa      360

uucacaauau gcgccaacgu uucuuuagac gaacgaucaa aauuagccua cgacguaaca      420

acacccugcg aaauaaaagc augcucacua acaugccuaa aaucaaaaaa caugcucacu      480

acaguaaaag accuaaccau gaaaacacuc aacccaacac acgacauaau agcccuaugc      540

gaauuugaaa acauaguaac aucaaaaaaa guaauaaucc caacauacuu aagaucgauc      600

ucagucagaa acaaagaccu aaauacacuc gaaaacauaa caacaacaga auuuaaaaac      660

gcaauaacaa acgcaaaaau aauaccauac ucaggacuac uccuaguaau aacaguaaca      720

gacaacaaag gagcauucaa auacauaaaa ccacaaucac aauucaucgu agaccucgga      780

gcauaccuag aaaaagaauc aauauacuac guaacaacaa acuggaaaca caccgccaca      840

agauucgcaa uaaaacccau ggaagacuaa ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9996
<211>  1365
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  9996
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaccua cgucaacaaa      120

cuacacgaag gcucaaccua caccgccgcc guccaauaca acguccucga aaaagacgac      180

gaccccgccu cccuaaccau cuggguuccc auguuccaau cauccaugcc cgccgaccuc      240

cucauaaaag aacuagccaa cgucaacauc cuagucaaac aaaucagcac ccccaaaggc      300

cccucccucc gcguaaugau caacucccgc uccgccgucc uagcccaaau gcccuccaaa      360

uuuacaaucu gcgccaacgu cucccucgac gaacgcucaa aacucgccua cgacgucacc      420

acacccugcg aaaucaaagc cugcucccuc accugccuca aaagcaaaaa uaugcuaacc      480

accgucaaag accuuaccau gaaaacccuc aaccccacuc acgacaucau agcccucugc      540

gaauuugaaa acaucgucac cuccaaaaaa gucaucaucc ccacauaccu ccgcuccauc      600

uccguccgca acaaagaccu caacacccuc gaaaacauca ccaccaccga auuuaaaaac      660

gccaucacca acgccaaaau cauccccuac uccggccucc uccucgucau caccguuacc      720

gacaacaaag gcgccuucaa auacaucaaa ccccaauccc aauucaucgu cgaccucgga      780

gccuaccuug aaaaagaguc caucuacuac gucaccacca acuggaaaca caccgccacc      840

cgauucgcca ucaaacccau ggaagacuaa ggacuaguga agggaacacc caaauuuaau      900

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca      960

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1020

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1080

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1140

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1200

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1320

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1365


<210>  9997
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  9997
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cgugaacaag      120

cuucacgaag gcuccacaua cacagcugcu guucaauaca augucuuaga aaaagacgau      180

gacccugcau cacuuacaau augggugccc auguuccaau caucuaugcc agcagauuua      240

cuuauaaaag aacuagcuaa ugucaacaua cuagugaaac aaauauccac acccaaggga      300

ccuucacuaa gagucaugau aaacucaaga agugcagugc uagcacaaau gcccagcaaa      360

uuuaccauau gcgcuaaugu guccuuggau gaaagaagca aacuagcaua ugauguaacc      420

acacccugug aaaucaaggc auguagucua acaugccuaa aaucaaaaaa uauguugacu      480

acaguuaaag aucucacuau gaagacacuc aacccuacac augauauuau ugcuuuaugu      540

gaauuugaaa acauaguaac aucaaaaaaa gucauaauac caacauaccu aagauccauc      600

agugucagaa auaaagaucu gaacacacuu gaaaauauaa caaccacuga auucaaaaau      660

gcuaucacaa augcaaaaau caucccuuac ucaggauuac uauuagucau cacagugacu      720

gacaacaaag gagcauucaa auacauaaag ccacaaaguc aauucauagu agaucuugga      780

gcuuaccuag aaaaagaaag uauauauuau guuaccacaa auuggaagca cacagcuaca      840

cgauuugcaa ucaaacccau ggaagauuaa ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  9998
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  9998
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua cacggccgcc guccaguaca acgugcucga gaaggacgac      180

gaccccgcgu cccugaccau cugggugccg auguuccaga gcuccaugcc cgccgaccug      240

cucaucaagg agcuggccaa cgucaacauc cuggugaagc agaucagcac ccccaagggg      300

cccucccucc gcgugaugau caacagccgg uccgccgucc uggcccagau gccgagcaag      360

uucaccaucu gcgcgaacgu gucccuggac gagcgcagca agcucgccua cgacgugacg      420

acccccugcg agaucaaggc cugcucccug accugccuca agagcaagaa caugcugacc      480

acggucaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgugac guccaagaag gugaucaucc ccaccuaccu gcggagcauc      600

uccguccgca acaaggaccu gaacacccuc gagaacauca ccacgaccga guucaagaac      660

gcgaucacca acgccaagau caucccguac agcggccugc ugcucgugau caccgugacg      720

gacaacaagg gggccuucaa guacaucaag ccccaguccc aguucaucgu cgaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacg      840

cgguucgcga ucaagcccau ggaggacuga ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  9999
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  9999
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgucaacaag      120

cuccacgagg gcuccaccua caccgccgcc guccaguaca acguccucga gaaggacgac      180

gaccccgccu cccucaccau cugggucccc auguuccagu ccuccaugcc cgccgaccuc      240

cucaucaagg agcucgccaa cgucaacauc cucgucaagc agaucuccac ccccaagggc      300

cccucccucc gcgucaugau caacucccgc uccgccgucc ucgcccagau gcccuccaag      360

uucaccaucu gcgccaacgu cucccucgac gagcgcucca agcucgccua cgacgucacc      420

acccccugcg agaucaaggc cugcucccuc accugccuca aguccaagaa caugcucacc      480

accgucaagg accucaccau gaagacccuc aaccccaccc acgacaucau cgcccucugc      540

gaguucgaga acaucgucac cuccaagaag gucaucaucc ccaccuaccu ccgcuccauc      600

uccguccgca acaaggaccu caacacccuc gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac uccggccucc uccucgucau caccgucacc      720

gacaacaagg gcgccuucaa guacaucaag ccccaguccc aguucaucgu cgaccucggc      780

gccuaccucg agaaggaguc caucuacuac gucaccacca acuggaagca caccgccacc      840

cgcuucgcca ucaagcccau ggaggacuga ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  10000
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  10000
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacugccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgcau cccuuacgau cugggugccu auguuccaau cuucaaugcc agccgaucug      240

uugauuaagg aauuagcgaa cguaaauaua cuggugaaac agaucaguac cccgaagggg      300

cccagccuaa gagucaugau uaacuccagg ucugcugugc ucgcccagau gccuucgaaa      360

uuuacaaucu gcgcaaaugu uucacuggac gagcggagca aacuugccua ugaugugacu      420

accccaugug aaauuaaggc uugcagucug acauguuuga aguccaagaa caugcucacc      480

acugucaaag accugacaau gaagacccug aaucccacgc augauaucau agcacucugc      540

gaguucgaga acaucgugac uucuaaaaag guaauuaucc cuaccuacuu acgcagcauu      600

uccguucgaa auaaggaccu gaacacacuu gaaaauauca cuaccacaga guuuaaaaac      660

gccauaacca augcuaagau uaucccauau ucaggauugc ugcuagugau uacggucacu      720

gauaacaaag gugccuucaa guacaucaaa ccccagaguc aauuuaucgu ggaccucggc      780

gcguaucugg aaaaggagag cauuuacuac gugacaacca auuggaaaca cacugcaaca      840

cguuucgcca uaaagccuau ggaggauuga ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  10001
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  10001
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgagg gcagcaccua caccgccgcc gugcaguaca acgugcugga gaaggacgac      180

gaccccgcca gccugaccau cugggugccc auguuccaga gcagcaugcc cgccgaccug      240

cugaucaagg agcuggccaa cgugaacauc cuggugaagc agaucagcac ccccaagggc      300

cccagccuga gagugaugau caacagcaga agcgccgugc uggcccagau gcccagcaag      360

uucaccaucu gcgccaacgu gagccuggac gagagaagca agcuggccua cgacgugacc      420

acccccugcg agaucaaggc cugcagccug accugccuga agagcaagaa caugcugacc      480

accgugaagg accugaccau gaagacccug aaccccaccc acgacaucau cgcccugugc      540

gaguucgaga acaucgugac cagcaagaag gugaucaucc ccaccuaccu gagaagcauc      600

agcgugagaa acaaggaccu gaacacccug gagaacauca ccaccaccga guucaagaac      660

gccaucacca acgccaagau cauccccuac agcggccugc ugcuggugau caccgugacc      720

gacaacaagg gcgccuucaa guacaucaag ccccagagcc aguucaucgu ggaccugggc      780

gccuaccugg agaaggagag caucuacuac gugaccacca acuggaagca caccgccacc      840

agauucgcca ucaagcccau ggaggacuga ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  10002
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  10002
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaccua cgugaacaag      120

cugcacgaag gcagcacaua uacggccgcu guccaguaca auguucucga gaaagacgau      180

gaccccgccu cccugaccau cugggugccu auguuccaau cuagcaugcc ggcggaucuu      240

cugauuaagg aacucgcuaa cgugaauauc cuggucaaac agauuuccac acccaagggg      300

ccuucucuua gagugaugau caacagccgg uccgccguuc uggcccagau gcccucuaaa      360

uuuaccauuu gcgcuaaugu gagccucgac gagcgcucca agcuggccua ugaugucaca      420

accccuugug aaaucaaggc uugcagccug acaugucuca aaucuaagaa caugcugacc      480

acggugaaag accuuaccau gaagacacug aaucccaccc augauaucau ugcccucugc      540

gaguucgaga acaucguuac auccaaaaag gugauuaucc cuaccuaccu gagaagcauu      600

ucuguccgga auaaggaccu uaacacgcug gaaaauauca caaccacaga guuuaaaaac      660

gcgauuacca augccaagau caucccguau uccggacucc ugcuggugau uaccgugaca      720

gauaacaaag gcgcuuucaa guacaucaaa ccccagagcc aauuuauugu cgaccucggg      780

gccuaucugg aaaaggaguc uaucuacuac guuacgacca auuggaaaca cacagcuacc      840

cgcuucgcca uuaagccuau ggaggauuga ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  10003
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  10003
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaacaua cguaaacaaa      120

cuacacgaag gauccacaua cacagcagca guacaauaca acguacuaga aaaagacgac      180

gacccagcau cuuuaaccau auggguacca auguuccaau caucaaugcc agcagaccuc      240

uuaauaaaag aacuagcaaa cguaaacauc cuagucaaac aaauaucaac acccaaagga      300

ccaucccuca gaguaaugau caacucaaga ucagcaguac uagcacaaau gccaucaaaa      360

uucacaauau gcgccaacgu uucuuuagac gaacgaucaa aauuagccua cgacguaaca      420

acacccugcg aaauaaaagc augcucacua acaugccuaa aaucaaaaaa caugcucacu      480

acaguaaaag accuaaccau gaaaacacuc aacccaacac acgacauaau agcccuaugc      540

gaauuugaaa acauaguaac aucaaaaaaa guaauaaucc caacauacuu aagaucgauc      600

ucagucagaa acaaagaccu aaauacacuc gaaaacauaa caacaacaga auuuaaaaac      660

gcaauaacaa acgcaaaaau aauaccauac ucaggacuac uccuaguaau aacaguaaca      720

gacaacaaag gagcauucaa auacauaaaa ccacaaucac aauucaucgu agaccucgga      780

gcauaccuag aaaaagaauc aauauacuac guaacaacaa acuggaaaca caccgccaca      840

agauucgcaa uaaaacccau ggaagacuaa ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  10004
<211>  1145
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  10004
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaccua cgucaacaaa      120

cuacacgaag gcucaaccua caccgccgcc guccaauaca acguccucga aaaagacgac      180

gaccccgccu cccuaaccau cuggguuccc auguuccaau cauccaugcc cgccgaccuc      240

cucauaaaag aacuagccaa cgucaacauc cuagucaaac aaaucagcac ccccaaaggc      300

cccucccucc gcguaaugau caacucccgc uccgccgucc uagcccaaau gcccuccaaa      360

uuuacaaucu gcgccaacgu cucccucgac gaacgcucaa aacucgccua cgacgucacc      420

acacccugcg aaaucaaagc cugcucccuc accugccuca aaagcaaaaa uaugcuaacc      480

accgucaaag accuuaccau gaaaacccuc aaccccacuc acgacaucau agcccucugc      540

gaauuugaaa acaucgucac cuccaaaaaa gucaucaucc ccacauaccu ccgcuccauc      600

uccguccgca acaaagaccu caacacccuc gaaaacauca ccaccaccga auuuaaaaac      660

gccaucacca acgccaaaau cauccccuac uccggccucc uccucgucau caccguuacc      720

gacaacaaag gcgccuucaa auacaucaaa ccccaauccc aauucaucgu cgaccucgga      780

gccuaccuug aaaaagaguc caucuacuac gucaccacca acuggaaaca caccgccacc      840

cgauucgcca ucaaacccau ggaagacuaa ggacuagugg aagcauuuuc cuggcugauu      900

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua      960

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1140

gaauu                                                                 1145


<210>  10005
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  10005
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguga acaagcuuca cgaaggcucc acauacacag cugcuguuca auacaauguc      240

uuagaaaaag acgaugaccc ugcaucacuu acaauauggg ugcccauguu ccaaucaucu      300

augccagcag auuuacuuau aaaagaacua gcuaauguca acauacuagu gaaacaaaua      360

uccacaccca agggaccuuc acuaagaguc augauaaacu caagaagugc agugcuagca      420

caaaugccca gcaaauuuac cauaugcgcu aauguguccu uggaugaaag aagcaaacua      480

gcauaugaug uaaccacacc cugugaaauc aaggcaugua gucuaacaug ccuaaaauca      540

aaaaauaugu ugacuacagu uaaagaucuc acuaugaaga cacucaaccc uacacaugau      600

auuauugcuu uaugugaauu ugaaaacaua guaacaucaa aaaaagucau aauaccaaca      660

uaccuaagau ccaucagugu cagaaauaaa gaucugaaca cacuugaaaa uauaacaacc      720

acugaauuca aaaaugcuau cacaaaugca aaaaucaucc cuuacucagg auuacuauua      780

gucaucacag ugacugacaa caaaggagca uucaaauaca uaaagccaca aagucaauuc      840

auaguagauc uuggagcuua ccuagaaaaa gaaaguauau auuauguuac cacaaauugg      900

aagcacacag cuacacgauu ugcaaucaaa cccauggaag auuaaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10006
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  10006
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacacgg ccgccgucca guacaacgug      240

cucgagaagg acgacgaccc cgcgucccug accaucuggg ugccgauguu ccagagcucc      300

augcccgccg accugcucau caaggagcug gccaacguca acauccuggu gaagcagauc      360

agcaccccca aggggcccuc ccuccgcgug augaucaaca gccgguccgc cguccuggcc      420

cagaugccga gcaaguucac caucugcgcg aacguguccc uggacgagcg cagcaagcuc      480

gccuacgacg ugacgacccc cugcgagauc aaggccugcu cccugaccug ccucaagagc      540

aagaacaugc ugaccacggu caaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gugacgucca agaaggugau cauccccacc      660

uaccugcgga gcaucuccgu ccgcaacaag gaccugaaca cccucgagaa caucaccacg      720

accgaguuca agaacgcgau caccaacgcc aagaucaucc cguacagcgg ccugcugcuc      780

gugaucaccg ugacggacaa caagggggcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccacgcgguu cgcgaucaag cccauggagg acugaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10007
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  10007
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguca acaagcucca cgagggcucc accuacaccg ccgccgucca guacaacguc      240

cucgagaagg acgacgaccc cgccucccuc accaucuggg uccccauguu ccaguccucc      300

augcccgccg accuccucau caaggagcuc gccaacguca acauccucgu caagcagauc      360

uccaccccca agggccccuc ccuccgcguc augaucaacu cccgcuccgc cguccucgcc      420

cagaugcccu ccaaguucac caucugcgcc aacgucuccc ucgacgagcg cuccaagcuc      480

gccuacgacg ucaccacccc cugcgagauc aaggccugcu cccucaccug ccucaagucc      540

aagaacaugc ucaccaccgu caaggaccuc accaugaaga cccucaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gucaccucca agaaggucau cauccccacc      660

uaccuccgcu ccaucuccgu ccgcaacaag gaccucaaca cccucgagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg ucaccgacaa caagggcgcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ucggcgccua ccucgagaag gaguccaucu acuacgucac caccaacugg      900

aagcacaccg ccacccgcuu cgccaucaag cccauggagg acugaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10008
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  10008
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacug ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgcaucccuu acgaucuggg ugccuauguu ccaaucuuca      300

augccagccg aucuguugau uaaggaauua gcgaacguaa auauacuggu gaaacagauc      360

aguaccccga aggggcccag ccuaagaguc augauuaacu ccaggucugc ugugcucgcc      420

cagaugccuu cgaaauuuac aaucugcgca aauguuucac uggacgagcg gagcaaacuu      480

gccuaugaug ugacuacccc augugaaauu aaggcuugca gucugacaug uuugaagucc      540

aagaacaugc ucaccacugu caaagaccug acaaugaaga cccugaaucc cacgcaugau      600

aucauagcac ucugcgaguu cgagaacauc gugacuucua aaaagguaau uaucccuacc      660

uacuuacgca gcauuuccgu ucgaaauaag gaccugaaca cacuugaaaa uaucacuacc      720

acagaguuua aaaacgccau aaccaaugcu aagauuaucc cauauucagg auugcugcua      780

gugauuacgg ucacugauaa caaaggugcc uucaaguaca ucaaacccca gagucaauuu      840

aucguggacc ucggcgcgua ucuggaaaag gagagcauuu acuacgugac aaccaauugg      900

aaacacacug caacacguuu cgccauaaag ccuauggagg auugaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10009
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  10009
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacaccg ccgccgugca guacaacgug      240

cuggagaagg acgacgaccc cgccagccug accaucuggg ugcccauguu ccagagcagc      300

augcccgccg accugcugau caaggagcug gccaacguga acauccuggu gaagcagauc      360

agcaccccca agggccccag ccugagagug augaucaaca gcagaagcgc cgugcuggcc      420

cagaugccca gcaaguucac caucugcgcc aacgugagcc uggacgagag aagcaagcug      480

gccuacgacg ugaccacccc cugcgagauc aaggccugca gccugaccug ccugaagagc      540

aagaacaugc ugaccaccgu gaaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ugugcgaguu cgagaacauc gugaccagca agaaggugau cauccccacc      660

uaccugagaa gcaucagcgu gagaaacaag gaccugaaca cccuggagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacagcgg ccugcugcug      780

gugaucaccg ugaccgacaa caagggcgcc uucaaguaca ucaagcccca gagccaguuc      840

aucguggacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccaccagauu cgccaucaag cccauggagg acugaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10010
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  10010
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacgg ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgccucccug accaucuggg ugccuauguu ccaaucuagc      300

augccggcgg aucuucugau uaaggaacuc gcuaacguga auauccuggu caaacagauu      360

uccacaccca aggggccuuc ucuuagagug augaucaaca gccgguccgc cguucuggcc      420

cagaugcccu cuaaauuuac cauuugcgcu aaugugagcc ucgacgagcg cuccaagcug      480

gccuaugaug ucacaacccc uugugaaauc aaggcuugca gccugacaug ucucaaaucu      540

aagaacaugc ugaccacggu gaaagaccuu accaugaaga cacugaaucc cacccaugau      600

aucauugccc ucugcgaguu cgagaacauc guuacaucca aaaaggugau uaucccuacc      660

uaccugagaa gcauuucugu ccggaauaag gaccuuaaca cgcuggaaaa uaucacaacc      720

acagaguuua aaaacgcgau uaccaaugcc aagaucaucc cguauuccgg acuccugcug      780

gugauuaccg ugacagauaa caaaggcgcu uucaaguaca ucaaacccca gagccaauuu      840

auugucgacc ucggggccua ucuggaaaag gagucuaucu acuacguuac gaccaauugg      900

aaacacacag cuacccgcuu cgccauuaag ccuauggagg auugaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10011
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  10011
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguaa acaaacuaca cgaaggaucc acauacacag cagcaguaca auacaacgua      240

cuagaaaaag acgacgaccc agcaucuuua accauauggg uaccaauguu ccaaucauca      300

augccagcag accucuuaau aaaagaacua gcaaacguaa acauccuagu caaacaaaua      360

ucaacaccca aaggaccauc ccucagagua augaucaacu caagaucagc aguacuagca      420

caaaugccau caaaauucac aauaugcgcc aacguuucuu uagacgaacg aucaaaauua      480

gccuacgacg uaacaacacc cugcgaaaua aaagcaugcu cacuaacaug ccuaaaauca      540

aaaaacaugc ucacuacagu aaaagaccua accaugaaaa cacucaaccc aacacacgac      600

auaauagccc uaugcgaauu ugaaaacaua guaacaucaa aaaaaguaau aaucccaaca      660

uacuuaagau cgaucucagu cagaaacaaa gaccuaaaua cacucgaaaa cauaacaaca      720

acagaauuua aaaacgcaau aacaaacgca aaaauaauac cauacucagg acuacuccua      780

guaauaacag uaacagacaa caaaggagca uucaaauaca uaaaaccaca aucacaauuc      840

aucguagacc ucggagcaua ccuagaaaaa gaaucaauau acuacguaac aacaaacugg      900

aaacacaccg ccacaagauu cgcaauaaaa cccauggaag acuaaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10012
<211>  1208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  10012
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

accuacguca acaaacuaca cgaaggcuca accuacaccg ccgccgucca auacaacguc      240

cucgaaaaag acgacgaccc cgccucccua accaucuggg uucccauguu ccaaucaucc      300

augcccgccg accuccucau aaaagaacua gccaacguca acauccuagu caaacaaauc      360

agcaccccca aaggccccuc ccuccgcgua augaucaacu cccgcuccgc cguccuagcc      420

caaaugcccu ccaaauuuac aaucugcgcc aacgucuccc ucgacgaacg cucaaaacuc      480

gccuacgacg ucaccacacc cugcgaaauc aaagccugcu cccucaccug ccucaaaagc      540

aaaaauaugc uaaccaccgu caaagaccuu accaugaaaa cccucaaccc cacucacgac      600

aucauagccc ucugcgaauu ugaaaacauc gucaccucca aaaaagucau cauccccaca      660

uaccuccgcu ccaucuccgu ccgcaacaaa gaccucaaca cccucgaaaa caucaccacc      720

accgaauuua aaaacgccau caccaacgcc aaaaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg uuaccgacaa caaaggcgcc uucaaauaca ucaaacccca aucccaauuc      840

aucgucgacc ucggagccua ccuugaaaaa gaguccaucu acuacgucac caccaacugg      900

aaacacaccg ccacccgauu cgccaucaaa cccauggaag acuaaggacu aguaauaagg      960

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa     1020

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1200

ccagaauu                                                              1208


<210>  10013
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  10013
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguga acaagcuuca cgaaggcucc acauacacag cugcuguuca auacaauguc      240

uuagaaaaag acgaugaccc ugcaucacuu acaauauggg ugcccauguu ccaaucaucu      300

augccagcag auuuacuuau aaaagaacua gcuaauguca acauacuagu gaaacaaaua      360

uccacaccca agggaccuuc acuaagaguc augauaaacu caagaagugc agugcuagca      420

caaaugccca gcaaauuuac cauaugcgcu aauguguccu uggaugaaag aagcaaacua      480

gcauaugaug uaaccacacc cugugaaauc aaggcaugua gucuaacaug ccuaaaauca      540

aaaaauaugu ugacuacagu uaaagaucuc acuaugaaga cacucaaccc uacacaugau      600

auuauugcuu uaugugaauu ugaaaacaua guaacaucaa aaaaagucau aauaccaaca      660

uaccuaagau ccaucagugu cagaaauaaa gaucugaaca cacuugaaaa uauaacaacc      720

acugaauuca aaaaugcuau cacaaaugca aaaaucaucc cuuacucagg auuacuauua      780

gucaucacag ugacugacaa caaaggagca uucaaauaca uaaagccaca aagucaauuc      840

auaguagauc uuggagcuua ccuagaaaaa gaaaguauau auuauguuac cacaaauugg      900

aagcacacag cuacacgauu ugcaaucaaa cccauggaag auuaaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10014
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  10014
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacacgg ccgccgucca guacaacgug      240

cucgagaagg acgacgaccc cgcgucccug accaucuggg ugccgauguu ccagagcucc      300

augcccgccg accugcucau caaggagcug gccaacguca acauccuggu gaagcagauc      360

agcaccccca aggggcccuc ccuccgcgug augaucaaca gccgguccgc cguccuggcc      420

cagaugccga gcaaguucac caucugcgcg aacguguccc uggacgagcg cagcaagcuc      480

gccuacgacg ugacgacccc cugcgagauc aaggccugcu cccugaccug ccucaagagc      540

aagaacaugc ugaccacggu caaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gugacgucca agaaggugau cauccccacc      660

uaccugcgga gcaucuccgu ccgcaacaag gaccugaaca cccucgagaa caucaccacg      720

accgaguuca agaacgcgau caccaacgcc aagaucaucc cguacagcgg ccugcugcuc      780

gugaucaccg ugacggacaa caagggggcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccacgcgguu cgcgaucaag cccauggagg acugaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10015
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  10015
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguca acaagcucca cgagggcucc accuacaccg ccgccgucca guacaacguc      240

cucgagaagg acgacgaccc cgccucccuc accaucuggg uccccauguu ccaguccucc      300

augcccgccg accuccucau caaggagcuc gccaacguca acauccucgu caagcagauc      360

uccaccccca agggccccuc ccuccgcguc augaucaacu cccgcuccgc cguccucgcc      420

cagaugcccu ccaaguucac caucugcgcc aacgucuccc ucgacgagcg cuccaagcuc      480

gccuacgacg ucaccacccc cugcgagauc aaggccugcu cccucaccug ccucaagucc      540

aagaacaugc ucaccaccgu caaggaccuc accaugaaga cccucaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gucaccucca agaaggucau cauccccacc      660

uaccuccgcu ccaucuccgu ccgcaacaag gaccucaaca cccucgagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg ucaccgacaa caagggcgcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ucggcgccua ccucgagaag gaguccaucu acuacgucac caccaacugg      900

aagcacaccg ccacccgcuu cgccaucaag cccauggagg acugaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10016
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  10016
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacug ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgcaucccuu acgaucuggg ugccuauguu ccaaucuuca      300

augccagccg aucuguugau uaaggaauua gcgaacguaa auauacuggu gaaacagauc      360

aguaccccga aggggcccag ccuaagaguc augauuaacu ccaggucugc ugugcucgcc      420

cagaugccuu cgaaauuuac aaucugcgca aauguuucac uggacgagcg gagcaaacuu      480

gccuaugaug ugacuacccc augugaaauu aaggcuugca gucugacaug uuugaagucc      540

aagaacaugc ucaccacugu caaagaccug acaaugaaga cccugaaucc cacgcaugau      600

aucauagcac ucugcgaguu cgagaacauc gugacuucua aaaagguaau uaucccuacc      660

uacuuacgca gcauuuccgu ucgaaauaag gaccugaaca cacuugaaaa uaucacuacc      720

acagaguuua aaaacgccau aaccaaugcu aagauuaucc cauauucagg auugcugcua      780

gugauuacgg ucacugauaa caaaggugcc uucaaguaca ucaaacccca gagucaauuu      840

aucguggacc ucggcgcgua ucuggaaaag gagagcauuu acuacgugac aaccaauugg      900

aaacacacug caacacguuu cgccauaaag ccuauggagg auugaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10017
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  10017
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacaccg ccgccgugca guacaacgug      240

cuggagaagg acgacgaccc cgccagccug accaucuggg ugcccauguu ccagagcagc      300

augcccgccg accugcugau caaggagcug gccaacguga acauccuggu gaagcagauc      360

agcaccccca agggccccag ccugagagug augaucaaca gcagaagcgc cgugcuggcc      420

cagaugccca gcaaguucac caucugcgcc aacgugagcc uggacgagag aagcaagcug      480

gccuacgacg ugaccacccc cugcgagauc aaggccugca gccugaccug ccugaagagc      540

aagaacaugc ugaccaccgu gaaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ugugcgaguu cgagaacauc gugaccagca agaaggugau cauccccacc      660

uaccugagaa gcaucagcgu gagaaacaag gaccugaaca cccuggagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacagcgg ccugcugcug      780

gugaucaccg ugaccgacaa caagggcgcc uucaaguaca ucaagcccca gagccaguuc      840

aucguggacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccaccagauu cgccaucaag cccauggagg acugaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10018
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  10018
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacgg ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgccucccug accaucuggg ugccuauguu ccaaucuagc      300

augccggcgg aucuucugau uaaggaacuc gcuaacguga auauccuggu caaacagauu      360

uccacaccca aggggccuuc ucuuagagug augaucaaca gccgguccgc cguucuggcc      420

cagaugcccu cuaaauuuac cauuugcgcu aaugugagcc ucgacgagcg cuccaagcug      480

gccuaugaug ucacaacccc uugugaaauc aaggcuugca gccugacaug ucucaaaucu      540

aagaacaugc ugaccacggu gaaagaccuu accaugaaga cacugaaucc cacccaugau      600

aucauugccc ucugcgaguu cgagaacauc guuacaucca aaaaggugau uaucccuacc      660

uaccugagaa gcauuucugu ccggaauaag gaccuuaaca cgcuggaaaa uaucacaacc      720

acagaguuua aaaacgcgau uaccaaugcc aagaucaucc cguauuccgg acuccugcug      780

gugauuaccg ugacagauaa caaaggcgcu uucaaguaca ucaaacccca gagccaauuu      840

auugucgacc ucggggccua ucuggaaaag gagucuaucu acuacguuac gaccaauugg      900

aaacacacag cuacccgcuu cgccauuaag ccuauggagg auugaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10019
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  10019
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguaa acaaacuaca cgaaggaucc acauacacag cagcaguaca auacaacgua      240

cuagaaaaag acgacgaccc agcaucuuua accauauggg uaccaauguu ccaaucauca      300

augccagcag accucuuaau aaaagaacua gcaaacguaa acauccuagu caaacaaaua      360

ucaacaccca aaggaccauc ccucagagua augaucaacu caagaucagc aguacuagca      420

caaaugccau caaaauucac aauaugcgcc aacguuucuu uagacgaacg aucaaaauua      480

gccuacgacg uaacaacacc cugcgaaaua aaagcaugcu cacuaacaug ccuaaaauca      540

aaaaacaugc ucacuacagu aaaagaccua accaugaaaa cacucaaccc aacacacgac      600

auaauagccc uaugcgaauu ugaaaacaua guaacaucaa aaaaaguaau aaucccaaca      660

uacuuaagau cgaucucagu cagaaacaaa gaccuaaaua cacucgaaaa cauaacaaca      720

acagaauuua aaaacgcaau aacaaacgca aaaauaauac cauacucagg acuacuccua      780

guaauaacag uaacagacaa caaaggagca uucaaauaca uaaaaccaca aucacaauuc      840

aucguagacc ucggagcaua ccuagaaaaa gaaucaauau acuacguaac aacaaacugg      900

aaacacaccg ccacaagauu cgcaauaaaa cccauggaag acuaaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10020
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  10020
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

accuacguca acaaacuaca cgaaggcuca accuacaccg ccgccgucca auacaacguc      240

cucgaaaaag acgacgaccc cgccucccua accaucuggg uucccauguu ccaaucaucc      300

augcccgccg accuccucau aaaagaacua gccaacguca acauccuagu caaacaaauc      360

agcaccccca aaggccccuc ccuccgcgua augaucaacu cccgcuccgc cguccuagcc      420

caaaugcccu ccaaauuuac aaucugcgcc aacgucuccc ucgacgaacg cucaaaacuc      480

gccuacgacg ucaccacacc cugcgaaauc aaagccugcu cccucaccug ccucaaaagc      540

aaaaauaugc uaaccaccgu caaagaccuu accaugaaaa cccucaaccc cacucacgac      600

aucauagccc ucugcgaauu ugaaaacauc gucaccucca aaaaagucau cauccccaca      660

uaccuccgcu ccaucuccgu ccgcaacaaa gaccucaaca cccucgaaaa caucaccacc      720

accgaauuua aaaacgccau caccaacgcc aaaaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg uuaccgacaa caaaggcgcc uucaaauaca ucaaacccca aucccaauuc      840

aucgucgacc ucggagccua ccuugaaaaa gaguccaucu acuacgucac caccaacugg      900

aaacacaccg ccacccgauu cgccaucaaa cccauggaag acuaaggacu aguacuggcu      960

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1020

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1080

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1200

gcucuuuuca gagccaccag aauu                                            1224


<210>  10021
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  10021
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguga acaagcuuca cgaaggcucc acauacacag cugcuguuca auacaauguc      240

uuagaaaaag acgaugaccc ugcaucacuu acaauauggg ugcccauguu ccaaucaucu      300

augccagcag auuuacuuau aaaagaacua gcuaauguca acauacuagu gaaacaaaua      360

uccacaccca agggaccuuc acuaagaguc augauaaacu caagaagugc agugcuagca      420

caaaugccca gcaaauuuac cauaugcgcu aauguguccu uggaugaaag aagcaaacua      480

gcauaugaug uaaccacacc cugugaaauc aaggcaugua gucuaacaug ccuaaaauca      540

aaaaauaugu ugacuacagu uaaagaucuc acuaugaaga cacucaaccc uacacaugau      600

auuauugcuu uaugugaauu ugaaaacaua guaacaucaa aaaaagucau aauaccaaca      660

uaccuaagau ccaucagugu cagaaauaaa gaucugaaca cacuugaaaa uauaacaacc      720

acugaauuca aaaaugcuau cacaaaugca aaaaucaucc cuuacucagg auuacuauua      780

gucaucacag ugacugacaa caaaggagca uucaaauaca uaaagccaca aagucaauuc      840

auaguagauc uuggagcuua ccuagaaaaa gaaaguauau auuauguuac cacaaauugg      900

aagcacacag cuacacgauu ugcaaucaaa cccauggaag auuaaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10022
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  10022
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacacgg ccgccgucca guacaacgug      240

cucgagaagg acgacgaccc cgcgucccug accaucuggg ugccgauguu ccagagcucc      300

augcccgccg accugcucau caaggagcug gccaacguca acauccuggu gaagcagauc      360

agcaccccca aggggcccuc ccuccgcgug augaucaaca gccgguccgc cguccuggcc      420

cagaugccga gcaaguucac caucugcgcg aacguguccc uggacgagcg cagcaagcuc      480

gccuacgacg ugacgacccc cugcgagauc aaggccugcu cccugaccug ccucaagagc      540

aagaacaugc ugaccacggu caaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gugacgucca agaaggugau cauccccacc      660

uaccugcgga gcaucuccgu ccgcaacaag gaccugaaca cccucgagaa caucaccacg      720

accgaguuca agaacgcgau caccaacgcc aagaucaucc cguacagcgg ccugcugcuc      780

gugaucaccg ugacggacaa caagggggcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccacgcgguu cgcgaucaag cccauggagg acugaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10023
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  10023
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguca acaagcucca cgagggcucc accuacaccg ccgccgucca guacaacguc      240

cucgagaagg acgacgaccc cgccucccuc accaucuggg uccccauguu ccaguccucc      300

augcccgccg accuccucau caaggagcuc gccaacguca acauccucgu caagcagauc      360

uccaccccca agggccccuc ccuccgcguc augaucaacu cccgcuccgc cguccucgcc      420

cagaugcccu ccaaguucac caucugcgcc aacgucuccc ucgacgagcg cuccaagcuc      480

gccuacgacg ucaccacccc cugcgagauc aaggccugcu cccucaccug ccucaagucc      540

aagaacaugc ucaccaccgu caaggaccuc accaugaaga cccucaaccc cacccacgac      600

aucaucgccc ucugcgaguu cgagaacauc gucaccucca agaaggucau cauccccacc      660

uaccuccgcu ccaucuccgu ccgcaacaag gaccucaaca cccucgagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg ucaccgacaa caagggcgcc uucaaguaca ucaagcccca gucccaguuc      840

aucgucgacc ucggcgccua ccucgagaag gaguccaucu acuacgucac caccaacugg      900

aagcacaccg ccacccgcuu cgccaucaag cccauggagg acugaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10024
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  10024
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacug ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgcaucccuu acgaucuggg ugccuauguu ccaaucuuca      300

augccagccg aucuguugau uaaggaauua gcgaacguaa auauacuggu gaaacagauc      360

aguaccccga aggggcccag ccuaagaguc augauuaacu ccaggucugc ugugcucgcc      420

cagaugccuu cgaaauuuac aaucugcgca aauguuucac uggacgagcg gagcaaacuu      480

gccuaugaug ugacuacccc augugaaauu aaggcuugca gucugacaug uuugaagucc      540

aagaacaugc ucaccacugu caaagaccug acaaugaaga cccugaaucc cacgcaugau      600

aucauagcac ucugcgaguu cgagaacauc gugacuucua aaaagguaau uaucccuacc      660

uacuuacgca gcauuuccgu ucgaaauaag gaccugaaca cacuugaaaa uaucacuacc      720

acagaguuua aaaacgccau aaccaaugcu aagauuaucc cauauucagg auugcugcua      780

gugauuacgg ucacugauaa caaaggugcc uucaaguaca ucaaacccca gagucaauuu      840

aucguggacc ucggcgcgua ucuggaaaag gagagcauuu acuacgugac aaccaauugg      900

aaacacacug caacacguuu cgccauaaag ccuauggagg auugaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10025
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  10025
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgagggcagc accuacaccg ccgccgugca guacaacgug      240

cuggagaagg acgacgaccc cgccagccug accaucuggg ugcccauguu ccagagcagc      300

augcccgccg accugcugau caaggagcug gccaacguga acauccuggu gaagcagauc      360

agcaccccca agggccccag ccugagagug augaucaaca gcagaagcgc cgugcuggcc      420

cagaugccca gcaaguucac caucugcgcc aacgugagcc uggacgagag aagcaagcug      480

gccuacgacg ugaccacccc cugcgagauc aaggccugca gccugaccug ccugaagagc      540

aagaacaugc ugaccaccgu gaaggaccug accaugaaga cccugaaccc cacccacgac      600

aucaucgccc ugugcgaguu cgagaacauc gugaccagca agaaggugau cauccccacc      660

uaccugagaa gcaucagcgu gagaaacaag gaccugaaca cccuggagaa caucaccacc      720

accgaguuca agaacgccau caccaacgcc aagaucaucc ccuacagcgg ccugcugcug      780

gugaucaccg ugaccgacaa caagggcgcc uucaaguaca ucaagcccca gagccaguuc      840

aucguggacc ugggcgccua ccuggagaag gagagcaucu acuacgugac caccaacugg      900

aagcacaccg ccaccagauu cgccaucaag cccauggagg acugaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10026
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  10026
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

accuacguga acaagcugca cgaaggcagc acauauacgg ccgcugucca guacaauguu      240

cucgagaaag acgaugaccc cgccucccug accaucuggg ugccuauguu ccaaucuagc      300

augccggcgg aucuucugau uaaggaacuc gcuaacguga auauccuggu caaacagauu      360

uccacaccca aggggccuuc ucuuagagug augaucaaca gccgguccgc cguucuggcc      420

cagaugcccu cuaaauuuac cauuugcgcu aaugugagcc ucgacgagcg cuccaagcug      480

gccuaugaug ucacaacccc uugugaaauc aaggcuugca gccugacaug ucucaaaucu      540

aagaacaugc ugaccacggu gaaagaccuu accaugaaga cacugaaucc cacccaugau      600

aucauugccc ucugcgaguu cgagaacauc guuacaucca aaaaggugau uaucccuacc      660

uaccugagaa gcauuucugu ccggaauaag gaccuuaaca cgcuggaaaa uaucacaacc      720

acagaguuua aaaacgcgau uaccaaugcc aagaucaucc cguauuccgg acuccugcug      780

gugauuaccg ugacagauaa caaaggcgcu uucaaguaca ucaaacccca gagccaauuu      840

auugucgacc ucggggccua ucuggaaaag gagucuaucu acuacguuac gaccaauugg      900

aaacacacag cuacccgcuu cgccauuaag ccuauggagg auugaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10027
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  10027
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

acauacguaa acaaacuaca cgaaggaucc acauacacag cagcaguaca auacaacgua      240

cuagaaaaag acgacgaccc agcaucuuua accauauggg uaccaauguu ccaaucauca      300

augccagcag accucuuaau aaaagaacua gcaaacguaa acauccuagu caaacaaaua      360

ucaacaccca aaggaccauc ccucagagua augaucaacu caagaucagc aguacuagca      420

caaaugccau caaaauucac aauaugcgcc aacguuucuu uagacgaacg aucaaaauua      480

gccuacgacg uaacaacacc cugcgaaaua aaagcaugcu cacuaacaug ccuaaaauca      540

aaaaacaugc ucacuacagu aaaagaccua accaugaaaa cacucaaccc aacacacgac      600

auaauagccc uaugcgaauu ugaaaacaua guaacaucaa aaaaaguaau aaucccaaca      660

uacuuaagau cgaucucagu cagaaacaaa gaccuaaaua cacucgaaaa cauaacaaca      720

acagaauuua aaaacgcaau aacaaacgca aaaauaauac cauacucagg acuacuccua      780

guaauaacag uaacagacaa caaaggagca uucaaauaca uaaaaccaca aucacaauuc      840

aucguagacc ucggagcaua ccuagaaaaa gaaucaauau acuacguaac aacaaacugg      900

aaacacaccg ccacaagauu cgcaauaaaa cccauggaag acuaaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10028
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  10028
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

accuacguca acaaacuaca cgaaggcuca accuacaccg ccgccgucca auacaacguc      240

cucgaaaaag acgacgaccc cgccucccua accaucuggg uucccauguu ccaaucaucc      300

augcccgccg accuccucau aaaagaacua gccaacguca acauccuagu caaacaaauc      360

agcaccccca aaggccccuc ccuccgcgua augaucaacu cccgcuccgc cguccuagcc      420

caaaugcccu ccaaauuuac aaucugcgcc aacgucuccc ucgacgaacg cucaaaacuc      480

gccuacgacg ucaccacacc cugcgaaauc aaagccugcu cccucaccug ccucaaaagc      540

aaaaauaugc uaaccaccgu caaagaccuu accaugaaaa cccucaaccc cacucacgac      600

aucauagccc ucugcgaauu ugaaaacauc gucaccucca aaaaagucau cauccccaca      660

uaccuccgcu ccaucuccgu ccgcaacaaa gaccucaaca cccucgaaaa caucaccacc      720

accgaauuua aaaacgccau caccaacgcc aaaaucaucc ccuacuccgg ccuccuccuc      780

gucaucaccg uuaccgacaa caaaggcgcc uucaaauaca ucaaacccca aucccaauuc      840

aucgucgacc ucggagccua ccuugaaaaa gaguccaucu acuacgucac caccaacugg      900

aaacacaccg ccacccgauu cgccaucaaa cccauggaag acuaaggacu aguguccacc      960

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1020

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10029
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  10029
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaaacauacg ugaacaagcu ucacgaaggc uccacauaca cagcugcugu ucaauacaau      120

gucuuagaaa aagacgauga cccugcauca cuuacaauau gggugcccau guuccaauca      180

ucuaugccag cagauuuacu uauaaaagaa cuagcuaaug ucaacauacu agugaaacaa      240

auauccacac ccaagggacc uucacuaaga gucaugauaa acucaagaag ugcagugcua      300

gcacaaaugc ccagcaaauu uaccauaugc gcuaaugugu ccuuggauga aagaagcaaa      360

cuagcauaug auguaaccac acccugugaa aucaaggcau guagucuaac augccuaaaa      420

ucaaaaaaua uguugacuac aguuaaagau cucacuauga agacacucaa cccuacacau      480

gauauuauug cuuuauguga auuugaaaac auaguaacau caaaaaaagu cauaauacca      540

acauaccuaa gauccaucag ugucagaaau aaagaucuga acacacuuga aaauauaaca      600

accacugaau ucaaaaaugc uaucacaaau gcaaaaauca ucccuuacuc aggauuacua      660

uuagucauca cagugacuga caacaaagga gcauucaaau acauaaagcc acaaagucaa      720

uucauaguag aucuuggagc uuaccuagaa aaagaaagua uauauuaugu uaccacaaau      780

uggaagcaca cagcuacacg auuugcaauc aaacccaugg aagauuaagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10030
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  10030
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca cggccgccgu ccaguacaac      120

gugcucgaga aggacgacga ccccgcgucc cugaccaucu gggugccgau guuccagagc      180

uccaugcccg ccgaccugcu caucaaggag cuggccaacg ucaacauccu ggugaagcag      240

aucagcaccc ccaaggggcc cucccuccgc gugaugauca acagccgguc cgccguccug      300

gcccagaugc cgagcaaguu caccaucugc gcgaacgugu cccuggacga gcgcagcaag      360

cucgccuacg acgugacgac ccccugcgag aucaaggccu gcucccugac cugccucaag      420

agcaagaaca ugcugaccac ggucaaggac cugaccauga agacccugaa ccccacccac      480

gacaucaucg cccucugcga guucgagaac aucgugacgu ccaagaaggu gaucaucccc      540

accuaccugc ggagcaucuc cguccgcaac aaggaccuga acacccucga gaacaucacc      600

acgaccgagu ucaagaacgc gaucaccaac gccaagauca ucccguacag cggccugcug      660

cucgugauca ccgugacgga caacaagggg gccuucaagu acaucaagcc ccagucccag      720

uucaucgucg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      780

uggaagcaca ccgccacgcg guucgcgauc aagcccaugg aggacugagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10031
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  10031
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaccuacg ucaacaagcu ccacgagggc uccaccuaca ccgccgccgu ccaguacaac      120

guccucgaga aggacgacga ccccgccucc cucaccaucu ggguccccau guuccagucc      180

uccaugcccg ccgaccuccu caucaaggag cucgccaacg ucaacauccu cgucaagcag      240

aucuccaccc ccaagggccc cucccuccgc gucaugauca acucccgcuc cgccguccuc      300

gcccagaugc ccuccaaguu caccaucugc gccaacgucu cccucgacga gcgcuccaag      360

cucgccuacg acgucaccac ccccugcgag aucaaggccu gcucccucac cugccucaag      420

uccaagaaca ugcucaccac cgucaaggac cucaccauga agacccucaa ccccacccac      480

gacaucaucg cccucugcga guucgagaac aucgucaccu ccaagaaggu caucaucccc      540

accuaccucc gcuccaucuc cguccgcaac aaggaccuca acacccucga gaacaucacc      600

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacuc cggccuccuc      660

cucgucauca ccgucaccga caacaagggc gccuucaagu acaucaagcc ccagucccag      720

uucaucgucg accucggcgc cuaccucgag aaggagucca ucuacuacgu caccaccaac      780

uggaagcaca ccgccacccg cuucgccauc aagcccaugg aggacugagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10032
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  10032
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cugccgcugu ccaguacaau      120

guucucgaga aagacgauga ccccgcaucc cuuacgaucu gggugccuau guuccaaucu      180

ucaaugccag ccgaucuguu gauuaaggaa uuagcgaacg uaaauauacu ggugaaacag      240

aucaguaccc cgaaggggcc cagccuaaga gucaugauua acuccagguc ugcugugcuc      300

gcccagaugc cuucgaaauu uacaaucugc gcaaauguuu cacuggacga gcggagcaaa      360

cuugccuaug augugacuac cccaugugaa auuaaggcuu gcagucugac auguuugaag      420

uccaagaaca ugcucaccac ugucaaagac cugacaauga agacccugaa ucccacgcau      480

gauaucauag cacucugcga guucgagaac aucgugacuu cuaaaaaggu aauuaucccu      540

accuacuuac gcagcauuuc cguucgaaau aaggaccuga acacacuuga aaauaucacu      600

accacagagu uuaaaaacgc cauaaccaau gcuaagauua ucccauauuc aggauugcug      660

cuagugauua cggucacuga uaacaaaggu gccuucaagu acaucaaacc ccagagucaa      720

uuuaucgugg accucggcgc guaucuggaa aaggagagca uuuacuacgu gacaaccaau      780

uggaaacaca cugcaacacg uuucgccaua aagccuaugg aggauugagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10033
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  10033
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgagggc agcaccuaca ccgccgccgu gcaguacaac      120

gugcuggaga aggacgacga ccccgccagc cugaccaucu gggugcccau guuccagagc      180

agcaugcccg ccgaccugcu gaucaaggag cuggccaacg ugaacauccu ggugaagcag      240

aucagcaccc ccaagggccc cagccugaga gugaugauca acagcagaag cgccgugcug      300

gcccagaugc ccagcaaguu caccaucugc gccaacguga gccuggacga gagaagcaag      360

cuggccuacg acgugaccac ccccugcgag aucaaggccu gcagccugac cugccugaag      420

agcaagaaca ugcugaccac cgugaaggac cugaccauga agacccugaa ccccacccac      480

gacaucaucg cccugugcga guucgagaac aucgugacca gcaagaaggu gaucaucccc      540

accuaccuga gaagcaucag cgugagaaac aaggaccuga acacccugga gaacaucacc      600

accaccgagu ucaagaacgc caucaccaac gccaagauca uccccuacag cggccugcug      660

cuggugauca ccgugaccga caacaagggc gccuucaagu acaucaagcc ccagagccag      720

uucaucgugg accugggcgc cuaccuggag aaggagagca ucuacuacgu gaccaccaac      780

uggaagcaca ccgccaccag auucgccauc aagcccaugg aggacugagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10034
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  10034
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaccuacg ugaacaagcu gcacgaaggc agcacauaua cggccgcugu ccaguacaau      120

guucucgaga aagacgauga ccccgccucc cugaccaucu gggugccuau guuccaaucu      180

agcaugccgg cggaucuucu gauuaaggaa cucgcuaacg ugaauauccu ggucaaacag      240

auuuccacac ccaaggggcc uucucuuaga gugaugauca acagccgguc cgccguucug      300

gcccagaugc ccucuaaauu uaccauuugc gcuaauguga gccucgacga gcgcuccaag      360

cuggccuaug augucacaac cccuugugaa aucaaggcuu gcagccugac augucucaaa      420

ucuaagaaca ugcugaccac ggugaaagac cuuaccauga agacacugaa ucccacccau      480

gauaucauug cccucugcga guucgagaac aucguuacau ccaaaaaggu gauuaucccu      540

accuaccuga gaagcauuuc uguccggaau aaggaccuua acacgcugga aaauaucaca      600

accacagagu uuaaaaacgc gauuaccaau gccaagauca ucccguauuc cggacuccug      660

cuggugauua ccgugacaga uaacaaaggc gcuuucaagu acaucaaacc ccagagccaa      720

uuuauugucg accucggggc cuaucuggaa aaggagucua ucuacuacgu uacgaccaau      780

uggaaacaca cagcuacccg cuucgccauu aagccuaugg aggauugagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10035
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  10035
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaaacauacg uaaacaaacu acacgaagga uccacauaca cagcagcagu acaauacaac      120

guacuagaaa aagacgacga cccagcaucu uuaaccauau ggguaccaau guuccaauca      180

ucaaugccag cagaccucuu aauaaaagaa cuagcaaacg uaaacauccu agucaaacaa      240

auaucaacac ccaaaggacc aucccucaga guaaugauca acucaagauc agcaguacua      300

gcacaaaugc caucaaaauu cacaauaugc gccaacguuu cuuuagacga acgaucaaaa      360

uuagccuacg acguaacaac acccugcgaa auaaaagcau gcucacuaac augccuaaaa      420

ucaaaaaaca ugcucacuac aguaaaagac cuaaccauga aaacacucaa cccaacacac      480

gacauaauag cccuaugcga auuugaaaac auaguaacau caaaaaaagu aauaauccca      540

acauacuuaa gaucgaucuc agucagaaac aaagaccuaa auacacucga aaacauaaca      600

acaacagaau uuaaaaacgc aauaacaaac gcaaaaauaa uaccauacuc aggacuacuc      660

cuaguaauaa caguaacaga caacaaagga gcauucaaau acauaaaacc acaaucacaa      720

uucaucguag accucggagc auaccuagaa aaagaaucaa uauacuacgu aacaacaaac      780

uggaaacaca ccgccacaag auucgcaaua aaacccaugg aagacuaagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10036
<211>  1157
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  10036
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaaaccuacg ucaacaaacu acacgaaggc ucaaccuaca ccgccgccgu ccaauacaac      120

guccucgaaa aagacgacga ccccgccucc cuaaccaucu ggguucccau guuccaauca      180

uccaugcccg ccgaccuccu cauaaaagaa cuagccaacg ucaacauccu agucaaacaa      240

aucagcaccc ccaaaggccc cucccuccgc guaaugauca acucccgcuc cgccguccua      300

gcccaaaugc ccuccaaauu uacaaucugc gccaacgucu cccucgacga acgcucaaaa      360

cucgccuacg acgucaccac acccugcgaa aucaaagccu gcucccucac cugccucaaa      420

agcaaaaaua ugcuaaccac cgucaaagac cuuaccauga aaacccucaa ccccacucac      480

gacaucauag cccucugcga auuugaaaac aucgucaccu ccaaaaaagu caucaucccc      540

acauaccucc gcuccaucuc cguccgcaac aaagaccuca acacccucga aaacaucacc      600

accaccgaau uuaaaaacgc caucaccaac gccaaaauca uccccuacuc cggccuccuc      660

cucgucauca ccguuaccga caacaaaggc gccuucaaau acaucaaacc ccaaucccaa      720

uucaucgucg accucggagc cuaccuugaa aaagagucca ucuacuacgu caccaccaac      780

uggaaacaca ccgccacccg auucgccauc aaacccaugg aagacuaagg acuagugcau      840

cacauuuaaa agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag      900

cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua      960

aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa     1020

ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1140

ucagagccac cagaauu                                                    1157


<210>  10037
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  10037
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

cauacgugaa caagcuucac gaaggcucca cauacacagc ugcuguucaa uacaaugucu      120

uagaaaaaga cgaugacccu gcaucacuua caauaugggu gcccauguuc caaucaucua      180

ugccagcaga uuuacuuaua aaagaacuag cuaaugucaa cauacuagug aaacaaauau      240

ccacacccaa gggaccuuca cuaagaguca ugauaaacuc aagaagugca gugcuagcac      300

aaaugcccag caaauuuacc auaugcgcua auguguccuu ggaugaaaga agcaaacuag      360

cauaugaugu aaccacaccc ugugaaauca aggcauguag ucuaacaugc cuaaaaucaa      420

aaaauauguu gacuacaguu aaagaucuca cuaugaagac acucaacccu acacaugaua      480

uuauugcuuu augugaauuu gaaaacauag uaacaucaaa aaaagucaua auaccaacau      540

accuaagauc caucaguguc agaaauaaag aucugaacac acuugaaaau auaacaacca      600

cugaauucaa aaaugcuauc acaaaugcaa aaaucauccc uuacucagga uuacuauuag      660

ucaucacagu gacugacaac aaaggagcau ucaaauacau aaagccacaa agucaauuca      720

uaguagaucu uggagcuuac cuagaaaaag aaaguauaua uuauguuacc acaaauugga      780

agcacacagc uacacgauuu gcaaucaaac ccauggaaga uuaaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10038
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1)

<400>  10038
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

ccuacgugaa caagcugcac gagggcagca ccuacacggc cgccguccag uacaacgugc      120

ucgagaagga cgacgacccc gcgucccuga ccaucugggu gccgauguuc cagagcucca      180

ugcccgccga ccugcucauc aaggagcugg ccaacgucaa cauccuggug aagcagauca      240

gcacccccaa ggggcccucc cuccgcguga ugaucaacag ccgguccgcc guccuggccc      300

agaugccgag caaguucacc aucugcgcga acgugucccu ggacgagcgc agcaagcucg      360

ccuacgacgu gacgaccccc ugcgagauca aggccugcuc ccugaccugc cucaagagca      420

agaacaugcu gaccacgguc aaggaccuga ccaugaagac ccugaacccc acccacgaca      480

ucaucgcccu cugcgaguuc gagaacaucg ugacguccaa gaaggugauc auccccaccu      540

accugcggag caucuccguc cgcaacaagg accugaacac ccucgagaac aucaccacga      600

ccgaguucaa gaacgcgauc accaacgcca agaucauccc guacagcggc cugcugcucg      660

ugaucaccgu gacggacaac aagggggccu ucaaguacau caagccccag ucccaguuca      720

ucgucgaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc accaacugga      780

agcacaccgc cacgcgguuc gcgaucaagc ccauggagga cugaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10039
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  10039
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

ccuacgucaa caagcuccac gagggcucca ccuacaccgc cgccguccag uacaacgucc      120

ucgagaagga cgacgacccc gccucccuca ccaucugggu ccccauguuc caguccucca      180

ugcccgccga ccuccucauc aaggagcucg ccaacgucaa cauccucguc aagcagaucu      240

ccacccccaa gggccccucc cuccgcguca ugaucaacuc ccgcuccgcc guccucgccc      300

agaugcccuc caaguucacc aucugcgcca acgucucccu cgacgagcgc uccaagcucg      360

ccuacgacgu caccaccccc ugcgagauca aggccugcuc ccucaccugc cucaagucca      420

agaacaugcu caccaccguc aaggaccuca ccaugaagac ccucaacccc acccacgaca      480

ucaucgcccu cugcgaguuc gagaacaucg ucaccuccaa gaaggucauc auccccaccu      540

accuccgcuc caucuccguc cgcaacaagg accucaacac ccucgagaac aucaccacca      600

ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacuccggc cuccuccucg      660

ucaucaccgu caccgacaac aagggcgccu ucaaguacau caagccccag ucccaguuca      720

ucgucgaccu cggcgccuac cucgagaagg aguccaucua cuacgucacc accaacugga      780

agcacaccgc cacccgcuuc gccaucaagc ccauggagga cugaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10040
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  10040
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

ccuacgugaa caagcugcac gaaggcagca cauauacugc cgcuguccag uacaauguuc      120

ucgagaaaga cgaugacccc gcaucccuua cgaucugggu gccuauguuc caaucuucaa      180

ugccagccga ucuguugauu aaggaauuag cgaacguaaa uauacuggug aaacagauca      240

guaccccgaa ggggcccagc cuaagaguca ugauuaacuc caggucugcu gugcucgccc      300

agaugccuuc gaaauuuaca aucugcgcaa auguuucacu ggacgagcgg agcaaacuug      360

ccuaugaugu gacuacccca ugugaaauua aggcuugcag ucugacaugu uugaagucca      420

agaacaugcu caccacuguc aaagaccuga caaugaagac ccugaauccc acgcaugaua      480

ucauagcacu cugcgaguuc gagaacaucg ugacuucuaa aaagguaauu aucccuaccu      540

acuuacgcag cauuuccguu cgaaauaagg accugaacac acuugaaaau aucacuacca      600

cagaguuuaa aaacgccaua accaaugcua agauuauccc auauucagga uugcugcuag      660

ugauuacggu cacugauaac aaaggugccu ucaaguacau caaaccccag agucaauuua      720

ucguggaccu cggcgcguau cuggaaaagg agagcauuua cuacgugaca accaauugga      780

aacacacugc aacacguuuc gccauaaagc cuauggagga uugaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10041
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  10041
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

ccuacgugaa caagcugcac gagggcagca ccuacaccgc cgccgugcag uacaacgugc      120

uggagaagga cgacgacccc gccagccuga ccaucugggu gcccauguuc cagagcagca      180

ugcccgccga ccugcugauc aaggagcugg ccaacgugaa cauccuggug aagcagauca      240

gcacccccaa gggccccagc cugagaguga ugaucaacag cagaagcgcc gugcuggccc      300

agaugcccag caaguucacc aucugcgcca acgugagccu ggacgagaga agcaagcugg      360

ccuacgacgu gaccaccccc ugcgagauca aggccugcag ccugaccugc cugaagagca      420

agaacaugcu gaccaccgug aaggaccuga ccaugaagac ccugaacccc acccacgaca      480

ucaucgcccu gugcgaguuc gagaacaucg ugaccagcaa gaaggugauc auccccaccu      540

accugagaag caucagcgug agaaacaagg accugaacac ccuggagaac aucaccacca      600

ccgaguucaa gaacgccauc accaacgcca agaucauccc cuacagcggc cugcugcugg      660

ugaucaccgu gaccgacaac aagggcgccu ucaaguacau caagccccag agccaguuca      720

ucguggaccu gggcgccuac cuggagaagg agagcaucua cuacgugacc accaacugga      780

agcacaccgc caccagauuc gccaucaagc ccauggagga cugaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10042
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  10042
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

ccuacgugaa caagcugcac gaaggcagca cauauacggc cgcuguccag uacaauguuc      120

ucgagaaaga cgaugacccc gccucccuga ccaucugggu gccuauguuc caaucuagca      180

ugccggcgga ucuucugauu aaggaacucg cuaacgugaa uauccugguc aaacagauuu      240

ccacacccaa ggggccuucu cuuagaguga ugaucaacag ccgguccgcc guucuggccc      300

agaugcccuc uaaauuuacc auuugcgcua augugagccu cgacgagcgc uccaagcugg      360

ccuaugaugu cacaaccccu ugugaaauca aggcuugcag ccugacaugu cucaaaucua      420

agaacaugcu gaccacggug aaagaccuua ccaugaagac acugaauccc acccaugaua      480

ucauugcccu cugcgaguuc gagaacaucg uuacauccaa aaaggugauu aucccuaccu      540

accugagaag cauuucuguc cggaauaagg accuuaacac gcuggaaaau aucacaacca      600

cagaguuuaa aaacgcgauu accaaugcca agaucauccc guauuccgga cuccugcugg      660

ugauuaccgu gacagauaac aaaggcgcuu ucaaguacau caaaccccag agccaauuua      720

uugucgaccu cggggccuau cuggaaaagg agucuaucua cuacguuacg accaauugga      780

aacacacagc uacccgcuuc gccauuaagc cuauggagga uugaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10043
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  10043
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

cauacguaaa caaacuacac gaaggaucca cauacacagc agcaguacaa uacaacguac      120

uagaaaaaga cgacgaccca gcaucuuuaa ccauaugggu accaauguuc caaucaucaa      180

ugccagcaga ccucuuaaua aaagaacuag caaacguaaa cauccuaguc aaacaaauau      240

caacacccaa aggaccaucc cucagaguaa ugaucaacuc aagaucagca guacuagcac      300

aaaugccauc aaaauucaca auaugcgcca acguuucuuu agacgaacga ucaaaauuag      360

ccuacgacgu aacaacaccc ugcgaaauaa aagcaugcuc acuaacaugc cuaaaaucaa      420

aaaacaugcu cacuacagua aaagaccuaa ccaugaaaac acucaaccca acacacgaca      480

uaauagcccu augcgaauuu gaaaacauag uaacaucaaa aaaaguaaua aucccaacau      540

acuuaagauc gaucucaguc agaaacaaag accuaaauac acucgaaaac auaacaacaa      600

cagaauuuaa aaacgcaaua acaaacgcaa aaauaauacc auacucagga cuacuccuag      660

uaauaacagu aacagacaac aaaggagcau ucaaauacau aaaaccacaa ucacaauuca      720

ucguagaccu cggagcauac cuagaaaaag aaucaauaua cuacguaaca acaaacugga      780

aacacaccgc cacaagauuc gcaauaaaac ccauggaaga cuaaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10044
<211>  1153
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  10044
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

ccuacgucaa caaacuacac gaaggcucaa ccuacaccgc cgccguccaa uacaacgucc      120

ucgaaaaaga cgacgacccc gccucccuaa ccaucugggu ucccauguuc caaucaucca      180

ugcccgccga ccuccucaua aaagaacuag ccaacgucaa cauccuaguc aaacaaauca      240

gcacccccaa aggccccucc cuccgcguaa ugaucaacuc ccgcuccgcc guccuagccc      300

aaaugcccuc caaauuuaca aucugcgcca acgucucccu cgacgaacgc ucaaaacucg      360

ccuacgacgu caccacaccc ugcgaaauca aagccugcuc ccucaccugc cucaaaagca      420

aaaauaugcu aaccaccguc aaagaccuua ccaugaaaac ccucaacccc acucacgaca      480

ucauagcccu cugcgaauuu gaaaacaucg ucaccuccaa aaaagucauc auccccacau      540

accuccgcuc caucuccguc cgcaacaaag accucaacac ccucgaaaac aucaccacca      600

ccgaauuuaa aaacgccauc accaacgcca aaaucauccc cuacuccggc cuccuccucg      660

ucaucaccgu uaccgacaac aaaggcgccu ucaaauacau caaaccccaa ucccaauuca      720

ucgucgaccu cggagccuac cuugaaaaag aguccaucua cuacgucacc accaacugga      780

aacacaccgc cacccgauuc gccaucaaac ccauggaaga cuaaggacua gugcaucaca      840

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      900

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      960

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1020

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1140

agccaccaga auu                                                        1153


<210>  10045
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (wt)

<400>  10045
gggagaaagc uuaccaugga aacauacgug aacaagcuuc acgaaggcuc cacauacaca       60

gcugcuguuc aauacaaugu cuuagaaaaa gacgaugacc cugcaucacu uacaauaugg      120

gugcccaugu uccaaucauc uaugccagca gauuuacuua uaaaagaacu agcuaauguc      180

aacauacuag ugaaacaaau auccacaccc aagggaccuu cacuaagagu caugauaaac      240

ucaagaagug cagugcuagc acaaaugccc agcaaauuua ccauaugcgc uaaugugucc      300

uuggaugaaa gaagcaaacu agcauaugau guaaccacac ccugugaaau caaggcaugu      360

agucuaacau gccuaaaauc aaaaaauaug uugacuacag uuaaagaucu cacuaugaag      420

acacucaacc cuacacauga uauuauugcu uuaugugaau uugaaaacau aguaacauca      480

aaaaaaguca uaauaccaac auaccuaaga uccaucagug ucagaaauaa agaucugaac      540

acacuugaaa auauaacaac cacugaauuc aaaaaugcua ucacaaaugc aaaaaucauc      600

ccuuacucag gauuacuauu agucaucaca gugacugaca acaaaggagc auucaaauac      660

auaaagccac aaagucaauu cauaguagau cuuggagcuu accuagaaaa agaaaguaua      720

uauuauguua ccacaaauug gaagcacaca gcuacacgau uugcaaucaa acccauggaa      780

gauuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10046
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt1) R7595

<400>  10046
gggagaaagc uuaccaugga gaccuacgug aacaagcugc acgagggcag caccuacacg       60

gccgccgucc aguacaacgu gcucgagaag gacgacgacc ccgcgucccu gaccaucugg      120

gugccgaugu uccagagcuc caugcccgcc gaccugcuca ucaaggagcu ggccaacguc      180

aacauccugg ugaagcagau cagcaccccc aaggggcccu cccuccgcgu gaugaucaac      240

agccgguccg ccguccuggc ccagaugccg agcaaguuca ccaucugcgc gaacgugucc      300

cuggacgagc gcagcaagcu cgccuacgac gugacgaccc ccugcgagau caaggccugc      360

ucccugaccu gccucaagag caagaacaug cugaccacgg ucaaggaccu gaccaugaag      420

acccugaacc ccacccacga caucaucgcc cucugcgagu ucgagaacau cgugacgucc      480

aagaagguga ucauccccac cuaccugcgg agcaucuccg uccgcaacaa ggaccugaac      540

acccucgaga acaucaccac gaccgaguuc aagaacgcga ucaccaacgc caagaucauc      600

ccguacagcg gccugcugcu cgugaucacc gugacggaca acaagggggc cuucaaguac      660

aucaagcccc agucccaguu caucgucgac cugggcgccu accuggagaa ggagagcauc      720

uacuacguga ccaccaacug gaagcacacc gccacgcggu ucgcgaucaa gcccauggag      780

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10047
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt2)

<400>  10047
gggagaaagc uuaccaugga gaccuacguc aacaagcucc acgagggcuc caccuacacc       60

gccgccgucc aguacaacgu ccucgagaag gacgacgacc ccgccucccu caccaucugg      120

guccccaugu uccaguccuc caugcccgcc gaccuccuca ucaaggagcu cgccaacguc      180

aacauccucg ucaagcagau cuccaccccc aagggccccu cccuccgcgu caugaucaac      240

ucccgcuccg ccguccucgc ccagaugccc uccaaguuca ccaucugcgc caacgucucc      300

cucgacgagc gcuccaagcu cgccuacgac gucaccaccc ccugcgagau caaggccugc      360

ucccucaccu gccucaaguc caagaacaug cucaccaccg ucaaggaccu caccaugaag      420

acccucaacc ccacccacga caucaucgcc cucugcgagu ucgagaacau cgucaccucc      480

aagaagguca ucauccccac cuaccuccgc uccaucuccg uccgcaacaa ggaccucaac      540

acccucgaga acaucaccac caccgaguuc aagaacgcca ucaccaacgc caagaucauc      600

cccuacuccg gccuccuccu cgucaucacc gucaccgaca acaagggcgc cuucaaguac      660

aucaagcccc agucccaguu caucgucgac cucggcgccu accucgagaa ggaguccauc      720

uacuacguca ccaccaacug gaagcacacc gccacccgcu ucgccaucaa gcccauggag      780

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10048
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt3)

<400>  10048
gggagaaagc uuaccaugga gaccuacgug aacaagcugc acgaaggcag cacauauacu       60

gccgcugucc aguacaaugu ucucgagaaa gacgaugacc ccgcaucccu uacgaucugg      120

gugccuaugu uccaaucuuc aaugccagcc gaucuguuga uuaaggaauu agcgaacgua      180

aauauacugg ugaaacagau caguaccccg aaggggccca gccuaagagu caugauuaac      240

uccaggucug cugugcucgc ccagaugccu ucgaaauuua caaucugcgc aaauguuuca      300

cuggacgagc ggagcaaacu ugccuaugau gugacuaccc caugugaaau uaaggcuugc      360

agucugacau guuugaaguc caagaacaug cucaccacug ucaaagaccu gacaaugaag      420

acccugaauc ccacgcauga uaucauagca cucugcgagu ucgagaacau cgugacuucu      480

aaaaagguaa uuaucccuac cuacuuacgc agcauuuccg uucgaaauaa ggaccugaac      540

acacuugaaa auaucacuac cacagaguuu aaaaacgcca uaaccaaugc uaagauuauc      600

ccauauucag gauugcugcu agugauuacg gucacugaua acaaaggugc cuucaaguac      660

aucaaacccc agagucaauu uaucguggac cucggcgcgu aucuggaaaa ggagagcauu      720

uacuacguga caaccaauug gaaacacacu gcaacacguu ucgccauaaa gccuauggag      780

gauugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10049
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt4)

<400>  10049
gggagaaagc uuaccaugga gaccuacgug aacaagcugc acgagggcag caccuacacc       60

gccgccgugc aguacaacgu gcuggagaag gacgacgacc ccgccagccu gaccaucugg      120

gugcccaugu uccagagcag caugcccgcc gaccugcuga ucaaggagcu ggccaacgug      180

aacauccugg ugaagcagau cagcaccccc aagggcccca gccugagagu gaugaucaac      240

agcagaagcg ccgugcuggc ccagaugccc agcaaguuca ccaucugcgc caacgugagc      300

cuggacgaga gaagcaagcu ggccuacgac gugaccaccc ccugcgagau caaggccugc      360

agccugaccu gccugaagag caagaacaug cugaccaccg ugaaggaccu gaccaugaag      420

acccugaacc ccacccacga caucaucgcc cugugcgagu ucgagaacau cgugaccagc      480

aagaagguga ucauccccac cuaccugaga agcaucagcg ugagaaacaa ggaccugaac      540

acccuggaga acaucaccac caccgaguuc aagaacgcca ucaccaacgc caagaucauc      600

cccuacagcg gccugcugcu ggugaucacc gugaccgaca acaagggcgc cuucaaguac      660

aucaagcccc agagccaguu caucguggac cugggcgccu accuggagaa ggagagcauc      720

uacuacguga ccaccaacug gaagcacacc gccaccagau ucgccaucaa gcccauggag      780

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10050
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt5)

<400>  10050
gggagaaagc uuaccaugga gaccuacgug aacaagcugc acgaaggcag cacauauacg       60

gccgcugucc aguacaaugu ucucgagaaa gacgaugacc ccgccucccu gaccaucugg      120

gugccuaugu uccaaucuag caugccggcg gaucuucuga uuaaggaacu cgcuaacgug      180

aauauccugg ucaaacagau uuccacaccc aaggggccuu cucuuagagu gaugaucaac      240

agccgguccg ccguucuggc ccagaugccc ucuaaauuua ccauuugcgc uaaugugagc      300

cucgacgagc gcuccaagcu ggccuaugau gucacaaccc cuugugaaau caaggcuugc      360

agccugacau gucucaaauc uaagaacaug cugaccacgg ugaaagaccu uaccaugaag      420

acacugaauc ccacccauga uaucauugcc cucugcgagu ucgagaacau cguuacaucc      480

aaaaagguga uuaucccuac cuaccugaga agcauuucug uccggaauaa ggaccuuaac      540

acgcuggaaa auaucacaac cacagaguuu aaaaacgcga uuaccaaugc caagaucauc      600

ccguauuccg gacuccugcu ggugauuacc gugacagaua acaaaggcgc uuucaaguac      660

aucaaacccc agagccaauu uauugucgac cucggggccu aucuggaaaa ggagucuauc      720

uacuacguua cgaccaauug gaaacacaca gcuacccgcu ucgccauuaa gccuauggag      780

gauugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10051
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt6)

<400>  10051
gggagaaagc uuaccaugga aacauacgua aacaaacuac acgaaggauc cacauacaca       60

gcagcaguac aauacaacgu acuagaaaaa gacgacgacc cagcaucuuu aaccauaugg      120

guaccaaugu uccaaucauc aaugccagca gaccucuuaa uaaaagaacu agcaaacgua      180

aacauccuag ucaaacaaau aucaacaccc aaaggaccau cccucagagu aaugaucaac      240

ucaagaucag caguacuagc acaaaugcca ucaaaauuca caauaugcgc caacguuucu      300

uuagacgaac gaucaaaauu agccuacgac guaacaacac ccugcgaaau aaaagcaugc      360

ucacuaacau gccuaaaauc aaaaaacaug cucacuacag uaaaagaccu aaccaugaaa      420

acacucaacc caacacacga cauaauagcc cuaugcgaau uugaaaacau aguaacauca      480

aaaaaaguaa uaaucccaac auacuuaaga ucgaucucag ucagaaacaa agaccuaaau      540

acacucgaaa acauaacaac aacagaauuu aaaaacgcaa uaacaaacgc aaaaauaaua      600

ccauacucag gacuacuccu aguaauaaca guaacagaca acaaaggagc auucaaauac      660

auaaaaccac aaucacaauu caucguagac cucggagcau accuagaaaa agaaucaaua      720

uacuacguaa caacaaacug gaaacacacc gccacaagau ucgcaauaaa acccauggaa      780

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10052
<211>  988
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P0DOE7.1__M (opt11)

<400>  10052
gggagaaagc uuaccaugga aaccuacguc aacaaacuac acgaaggcuc aaccuacacc       60

gccgccgucc aauacaacgu ccucgaaaaa gacgacgacc ccgccucccu aaccaucugg      120

guucccaugu uccaaucauc caugcccgcc gaccuccuca uaaaagaacu agccaacguc      180

aacauccuag ucaaacaaau cagcaccccc aaaggccccu cccuccgcgu aaugaucaac      240

ucccgcuccg ccguccuagc ccaaaugccc uccaaauuua caaucugcgc caacgucucc      300

cucgacgaac gcucaaaacu cgccuacgac gucaccacac ccugcgaaau caaagccugc      360

ucccucaccu gccucaaaag caaaaauaug cuaaccaccg ucaaagaccu uaccaugaaa      420

acccucaacc ccacucacga caucauagcc cucugcgaau uugaaaacau cgucaccucc      480

aaaaaaguca ucauccccac auaccuccgc uccaucuccg uccgcaacaa agaccucaac      540

acccucgaaa acaucaccac caccgaauuu aaaaacgcca ucaccaacgc caaaaucauc      600

cccuacuccg gccuccuccu cgucaucacc guuaccgaca acaaaggcgc cuucaaauac      660

aucaaacccc aaucccaauu caucgucgac cucggagccu accuugaaaa agaguccauc      720

uacuacguca ccaccaacug gaaacacacc gccacccgau ucgccaucaa acccauggaa      780

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      840

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      960

aaaggcucuu uucagagcca ccagaauu                                         988


<210>  10053
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(Memphis-37)__AIY60638.1__M

<400>  10053

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10054
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__O42049.1__M

<400>  10054

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Pro Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10055
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAR14263.1__M

<400>  10055

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10056
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAX23991.1__M

<400>  10056

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Leu 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10057
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63375.1__M

<400>  10057

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Ile Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10058
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63408.1__M

<400>  10058

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10059
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63441.1__M

<400>  10059

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Ser Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10060
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63517.1__M

<400>  10060

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asx Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10061
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63583.1__M

<400>  10061

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10062
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55219.1__M

<400>  10062

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Ser Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Ile Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10063
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55516.1__M

<400>  10063

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Ile Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10064
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55549.1__M

<400>  10064

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Ile Glu Asp 
                245                 250                 255     


<210>  10065
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95387.1__M

<400>  10065

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Met 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10066
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28503.1__M

<400>  10066

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Arg Pro Leu Glu Asp 
                245                 250                 255     


<210>  10067
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28525.1__M

<400>  10067

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10068
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28547.1__M

<400>  10068

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Ile Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10069
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28679.1__M

<400>  10069

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Pro Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ser Met Pro Ser Lys Arg Val Val Ile 
145                 150                 155                 160 


Pro Thr Tyr Ile Arg Ser Ile Ser Leu Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10070
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN92845.1__M

<400>  10070

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Asn Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10071
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGT75332.1__M

<400>  10071

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala His Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10072
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83627.1__M

<400>  10072

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10073
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83757.1__M

<400>  10073

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Gln Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10074
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83921.1__M

<400>  10074

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asn Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10075
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA84064.1__M

<400>  10075

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Ala Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10076
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHJ60040.1__M

<400>  10076

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Thr Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10077
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80767.1__M

<400>  10077

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Lys Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10078
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80797.1__M

<400>  10078

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Val Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10079
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80987.1__M

<400>  10079

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Ser Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Thr Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10080
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81377.1__M

<400>  10080

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Ile Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10081
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81387.1__M

<400>  10081

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Ile Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Ile Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10082
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57072.1__M

<400>  10082

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Ile Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Ser Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10083
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21394.1__M

<400>  10083

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10084
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63191.1__M

<400>  10084

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Ser Asp Val Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10085
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY70195.1__M

<400>  10085

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Leu Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Glu Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10086
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY70239.1__M

<400>  10086

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Leu Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10087
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95978.1__M

<400>  10087

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Ser Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10088
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ96022.1__M

<400>  10088

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Ser Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10089
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44523.1__M

<400>  10089

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Ser Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Phe Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10090
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44599.1__M

<400>  10090

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10091
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44700.1__M

<400>  10091

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Ser Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Phe Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10092
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44768.1__M

<400>  10092

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Val Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10093
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69877.1__M

<400>  10093

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asn Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10094
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45857.1__M

<400>  10094

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Ile Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10095
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66379.1__M

<400>  10095

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Ile Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10096
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66401.1__M

<400>  10096

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Ser Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10097
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66665.1__M

<400>  10097

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Ser Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10098
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66995.1__M

<400>  10098

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Ile Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10099
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77696.1__M

<400>  10099

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Ser Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10100
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78378.1__M

<400>  10100

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10101
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80064.1__M

<400>  10101

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Ser Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10102
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80075.1__M

<400>  10102

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Thr Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10103
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80152.1__M

<400>  10103

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Ser Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10104
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80196.1__M

<400>  10104

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Ala Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10105
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80306.1__M

<400>  10105

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asn Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10106
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80515.1__M

<400>  10106

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Val Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10107
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48207.1__M

<400>  10107

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Ile Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10108
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48306.1__M

<400>  10108

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10109
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48405.1__M

<400>  10109

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Thr Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10110
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOY38332.1__M

<400>  10110

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Leu 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Ile Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10111
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78666.1__M

<400>  10111

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Ser Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10112
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78699.1__M

<400>  10112

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Lys Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Thr Met Thr Ser Lys Arg Val Thr Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10113
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78908.1__M

<400>  10113

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Arg Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10114
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB66380.1__M

<400>  10114

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Thr Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10115
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB66413.1__M

<400>  10115

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Asn Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10116
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB66446.1__M

<400>  10116

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Gly Lys His Thr Gly Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10117
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARN61504.1__M

<400>  10117

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Leu 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Ala Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Leu Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10118
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARQ15952.1__M

<400>  10118

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Ile Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Glu Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10119
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28380.1__M

<400>  10119

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Ser Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10120
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28424.1__M

<400>  10120

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Ser Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10121
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASL69314.1__M

<400>  10121

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Ile Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Arg His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10122
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASL69346.1__M

<400>  10122

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Gly Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10123
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASL69350.1__M

<400>  10123

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Gly Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10124
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASV49529.1__M

<400>  10124

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Lys Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10125
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ATV81351.1__M

<400>  10125

Met Glu Thr Tyr Val Asn Lys Leu Pro Tyr Val Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10126
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68267.1__M

<400>  10126

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Ile Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10127
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68332.1__M

<400>  10127

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Pro Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10128
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68343.1__M

<400>  10128

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Val Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Ser Ile Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Thr Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Asn Phe Ile Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Ser Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Thr Met Thr Ser Lys Arg Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Lys Asn Lys Asp Leu Asn Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Leu Glu Asp 
                245                 250                 255     


<210>  10129
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__NP_044593.1__M

<400>  10129

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Asn Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10130
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P24615.1__M

<400>  10130

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Ile Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Ile Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Ile Ser Ala Asp Met Leu 
        35                  40                  45              


Ile Lys Glu Leu Ile Asn Val Asn Ile Leu Val Arg Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Lys Ile Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Ile Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Arg Val Val Ile 
145                 150                 155                 160 


Pro Thr Phe Leu Arg Ser Ile Asn Val Lys Ala Lys Asp Leu Asp Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Lys Phe Ser Ile Lys Pro Ile Glu Asp 
                245                 250                 255     


<210>  10131
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__Q84131.1__M

<400>  10131

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Ile Ser Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ile Asn Val Asn Ile Leu Val Arg Gln Ile Ser Thr 
    50                  55                  60                  


Leu Lys Gly Pro Ser Leu Lys Ile Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Asn Lys Phe Thr Ile Ser Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Glu Arg Ser Lys Leu Ala Tyr Asp Ile Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Val Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Phe Asn Pro Thr His Glu Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Met Thr Ser Lys Lys Val Val Ile 
145                 150                 155                 160 


Pro Thr Phe Leu Arg Ser Ile Asn Val Lys Ala Lys Asp Leu Asp Ser 
                165                 170                 175     


Leu Glu Asn Ile Ala Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ala Gly Leu Val Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ser Ile Lys Pro Ile Glu Asp 
                245                 250                 255     


<210>  10132
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__2VQP_A__M

<400>  10132

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Asp Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Arg Glu Asp 
                245                 250                 255     


<210>  10133
<211>  256
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__2YKD_A__M

<400>  10133

Met Glu Thr Tyr Val Asn Lys Leu His Glu Gly Ser Thr Tyr Thr Ala 
1               5                   10                  15      


Ala Val Gln Tyr Asn Val Leu Glu Lys Asp Asp Asp Pro Ala Ser Leu 
            20                  25                  30          


Thr Ile Trp Val Pro Met Phe Gln Ser Ser Met Pro Ala Asp Leu Leu 
        35                  40                  45              


Ile Lys Glu Leu Ala Asn Val Asn Ile Leu Val Lys Gln Ile Ser Thr 
    50                  55                  60                  


Pro Lys Gly Pro Ser Leu Arg Val Met Ile Asn Ser Arg Ser Ala Val 
65                  70                  75                  80  


Leu Ala Gln Met Pro Ser Lys Phe Thr Ile Cys Ala Asn Val Ser Leu 
                85                  90                  95      


Asp Asp Arg Ser Lys Leu Ala Tyr Asp Val Thr Thr Pro Cys Glu Ile 
            100                 105                 110         


Lys Ala Cys Ser Leu Thr Cys Leu Lys Ser Lys Asn Met Leu Thr Thr 
        115                 120                 125             


Val Lys Asp Leu Thr Met Lys Thr Leu Asn Pro Thr His Asp Ile Ile 
    130                 135                 140                 


Ala Leu Cys Glu Phe Glu Asn Ile Val Thr Ser Lys Lys Val Ile Ile 
145                 150                 155                 160 


Pro Thr Tyr Leu Arg Ser Ile Ser Val Arg Asn Lys Asp Leu Asn Thr 
                165                 170                 175     


Leu Glu Asn Ile Thr Thr Thr Glu Phe Lys Asn Ala Ile Thr Asn Ala 
            180                 185                 190         


Lys Ile Ile Pro Tyr Ser Gly Leu Leu Leu Val Ile Thr Val Thr Asp 
        195                 200                 205             


Asn Lys Gly Ala Phe Lys Tyr Ile Lys Pro Gln Ser Gln Phe Ile Val 
    210                 215                 220                 


Asp Leu Gly Ala Tyr Leu Glu Lys Glu Ser Ile Tyr Tyr Val Thr Thr 
225                 230                 235                 240 


Asn Trp Lys His Thr Ala Thr Arg Phe Ala Ile Lys Pro Met Glu Asp 
                245                 250                 255     


<210>  10134
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(A2)__P03418.1__N

<400>  10134

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10135
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from 
       HRSV(A2)__P03418.1__N

<400>  10135
auggcucuua gcaaagucaa guugaaugau acacucaaca aagaucaacu ucugucaucc       60

agcaaauaca ccauccaacg gagcacagga gauaguauug auacuccuaa uuaugaugug      120

cagaaacaca ucaauaaguu auguggcaug uuauuaauca cagaagaugc uaaucauaaa      180

uucacugggu uaauagguau guuauaugcg augucuaggu uaggaagaga agacaccaua      240

aaaauacuca gagaugcggg auaucaugua aaagcaaaug gaguagaugu aacaacacau      300

cgucaagaca uuaauggaaa agaaaugaaa uuugaagugu uaacauuggc aagcuuaaca      360

acugaaauuc aaaucaacau ugagauagaa ucuagaaaau ccuacaaaaa aaugcuaaaa      420

gaaaugggag agguagcucc agaauacagg caugacucuc cugauugugg gaugauaaua      480

uuauguauag cagcauuagu aauaacuaaa uuagcagcag gggacagauc uggucuuaca      540

gccgugauua ggagagcuaa uaauguccua aaaaaugaaa ugaaacguua caaaggcuua      600

cuacccaagg acauagccaa cagcuucuau gaaguguuug aaaaacaucc ccacuuuaua      660

gauguuuuug uucauuuugg uauagcacaa ucuucuacca gagguggcag uagaguugaa      720

gggauuuuug caggauuguu uaugaaugcc uauggugcag ggcaagugau guuacggugg      780

ggagucuuag caaaaucagu uaaaaauauu auguuaggac augcuagugu gcaagcagaa      840

auggaacaag uuguugaggu uuaugaauau gcccaaaaau ugggugguga agcaggauuc      900

uaccauauau ugaacaaccc aaaagcauca uuauuaucuu ugacucaauu uccucacuuc      960

uccaguguag uauuaggcaa ugcugcuggc cuaggcauaa ugggagagua cagagguaca     1020

ccgaggaauc aagaucuaua ugaugcagca aaggcauaug cugaacaacu caaagaaaau     1080

ggugugauua acuacagugu acuagacuug acagcagaag aacuagaggc uaucaaacau     1140

cagcuuaauc caaaagauaa ugauguagag cuuuga                               1176


<210>  10136
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__P03418.1__N

<400>  10136
auggcccuga gcaaggugaa gcucaacgac acccugaaca aggaccagcu gcucuccagc       60

uccaaguaca ccauccagcg cagcaccggc gacuccaucg acacccccaa cuacgacguc      120

cagaagcaca ucaacaagcu gugcgggaug cugcucauca ccgaggacgc caaccacaag      180

uucaccggcc ugaucgggau gcuguacgcg augagccggc ucggccgcga ggacacgauc      240

aagauccugc gggacgccgg guaccacgug aaggccaacg gcguggacgu caccacccac      300

cgccaggaca ucaacggcaa ggagaugaag uucgaggugc ugacccucgc cucccugacg      360

accgagaucc agaucaacau cgagaucgag agccggaagu ccuacaagaa gaugcugaag      420

gagauggggg agguggcccc ggaguaccgc cacgacagcc ccgacugcgg caugaucauc      480

cucugcaucg cggcccuggu caucaccaag cuggccgccg gggaccgguc cggccucacc      540

gcggugaucc gccgggccaa caacgugcug aagaacgaga ugaagcgcua caaggggcug      600

cuccccaagg acaucgccaa cagcuucuac gaggucuucg agaagcaccc ccacuucauc      660

gacguguucg ugcacuucgg caucgcccag uccagcacgc ggggcggguc ccgcgucgag      720

ggcaucuucg ccgggcuguu caugaacgcg uacggcgccg gccaggugau gcugcggugg      780

ggcgugcucg ccaagagcgu caagaacauc augcuggggc acgccuccgu gcaggccgag      840

auggagcagg ucguggaggu guacgaguac gcgcagaagc ucgggggcga ggccggguuc      900

uaccacaucc ugaacaaccc gaaggccagc cugcuguccc ucacccaguu cccccacuuc      960

agcagcgugg uccugggcaa cgccgccggc cuggggauca ugggcgagua ccgcgggacg     1020

ccccggaacc aggaccucua cgacgcggcc aaggccuacg ccgagcagcu gaaggagaac     1080

ggcgugauca acuacuccgu gcuggaccuc accgccgagg agcuggaggc gaucaagcac     1140

cagcugaacc ccaaggacaa cgacgucgag cucuga                               1176


<210>  10137
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__P03418.1__N

<400>  10137
auggcccucu ccaaggucaa gcucaacgac acccucaaca aggaccagcu ccucuccucc       60

uccaaguaca ccauccagcg cuccaccggc gacuccaucg acacccccaa cuacgacguc      120

cagaagcaca ucaacaagcu cugcggcaug cuccucauca ccgaggacgc caaccacaag      180

uucaccggcc ucaucggcau gcucuacgcc augucccgcc ucggccgcga ggacaccauc      240

aagauccucc gcgacgccgg cuaccacguc aaggccaacg gcgucgacgu caccacccac      300

cgccaggaca ucaacggcaa ggagaugaag uucgaggucc ucacccucgc cucccucacc      360

accgagaucc agaucaacau cgagaucgag ucccgcaagu ccuacaagaa gaugcucaag      420

gagaugggcg aggucgcccc cgaguaccgc cacgacuccc ccgacugcgg caugaucauc      480

cucugcaucg ccgcccucgu caucaccaag cucgccgccg gcgaccgcuc cggccucacc      540

gccgucaucc gccgcgccaa caacguccuc aagaacgaga ugaagcgcua caagggccuc      600

cuccccaagg acaucgccaa cuccuucuac gaggucuucg agaagcaccc ccacuucauc      660

gacgucuucg uccacuucgg caucgcccag uccuccaccc gcggcggcuc ccgcgucgag      720

ggcaucuucg ccggccucuu caugaacgcc uacggcgccg gccaggucau gcuccgcugg      780

ggcguccucg ccaaguccgu caagaacauc augcucggcc acgccuccgu ccaggccgag      840

auggagcagg ucgucgaggu cuacgaguac gcccagaagc ucggcggcga ggccggcuuc      900

uaccacaucc ucaacaaccc caaggccucc cuccucuccc ucacccaguu cccccacuuc      960

uccuccgucg uccucggcaa cgccgccggc cucggcauca ugggcgagua ccgcggcacc     1020

ccccgcaacc aggaccucua cgacgccgcc aaggccuacg ccgagcagcu caaggagaac     1080

ggcgucauca acuacuccgu ccucgaccuc accgccgagg agcucgaggc caucaagcac     1140

cagcucaacc ccaaggacaa cgacgucgag cucuga                               1176


<210>  10138
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__P03418.1__N

<400>  10138
auggcccuga gcaaggugaa acucaacgac acccuuaaua aggaucagcu guuguccucu       60

ucaaaauaca caauccaaag aaguacuggc gacagcauug auacgcccaa cuaugacguc      120

cagaagcaca uaaauaaauu augcgggaug cugcuaauca ccgaggaugc uaaccauaag      180

uucacaggac ucauugguau gcuguacgca auguccaggc uuggccggga agacacuauc      240

aagauucugc gcgaugccgg guaucacguu aaagcgaaug gaguggacgu aaccacacau      300

cgacaggaua ucaacggcaa ggagaugaaa uuugaagugu ugacccucgc uucucugacu      360

acagagauac agaucaauau ugaaaucgag ucgcguaagu cauacaaaaa gaugcugaag      420

gagaugggug aagucgcccc ugaguauaga cacgacagcc cagauugugg gaugauuauc      480

cucugcauag cagccuuagu gauuaccaaa cuggcugcag gagacaggag uggccuuacg      540

gccguuaucc ggcgcgcuaa caauguguug aagaacgaaa ugaaaagaua caagggccug      600

cuaccgaaag auauugccaa uuccuucuau gaggucuuug agaagcaucc ccacuucauc      660

gacguguuug uacacuucgg gaucgcgcaa ucuagcacua ggggagguuc ccggguugaa      720

ggcauuuuug caggacucuu caugaacgcc uacggggcug gccaggugau gcugcgcugg      780

gguguccuug ccaaaucagu gaagaauaua augcuggggc augcaagugu gcaggcugag      840

auggaacagg ucguugaggu guacgaauau gcccaaaagu ugggaggcga ggcgggcuuu      900

uaccacaucc ucaacaaucc uaaagccagc cuguuaucuc ugacccaguu cccacauuuu      960

uccucaguag ugcucgggaa cgcagcugga cuugguauua ugggcgagua ucgagggaca     1020

cccagaaacc aggaccugua cgaugccgcu aaggccuaug cagaacaguu gaaagagaau     1080

ggagucauca acuacagcgu gcuagaccug acugccgagg aacucgaagc uauaaagcac     1140

caacugaauc cuaaagauaa cgacguugag cuuuga                               1176


<210>  10139
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__P03418.1__N

<400>  10139
auggcccuga gcaaggugaa gcugaacgac acccugaaca aggaccagcu gcugagcagc       60

agcaaguaca ccauccagag aagcaccggc gacagcaucg acacccccaa cuacgacgug      120

cagaagcaca ucaacaagcu gugcggcaug cugcugauca ccgaggacgc caaccacaag      180

uucaccggcc ugaucggcau gcuguacgcc augagcagac ugggcagaga ggacaccauc      240

aagauccuga gagacgccgg cuaccacgug aaggccaacg gcguggacgu gaccacccac      300

agacaggaca ucaacggcaa ggagaugaag uucgaggugc ugacccuggc cagccugacc      360

accgagaucc agaucaacau cgagaucgag agcagaaaga gcuacaagaa gaugcugaag      420

gagaugggcg agguggcccc cgaguacaga cacgacagcc ccgacugcgg caugaucauc      480

cugugcaucg ccgcccuggu gaucaccaag cuggccgccg gcgacagaag cggccugacc      540

gccgugauca gaagagccaa caacgugcug aagaacgaga ugaagagaua caagggccug      600

cugcccaagg acaucgccaa cagcuucuac gagguguucg agaagcaccc ccacuucauc      660

gacguguucg ugcacuucgg caucgcccag agcagcacca gaggcggcag cagaguggag      720

ggcaucuucg ccggccuguu caugaacgcc uacggcgccg gccaggugau gcugagaugg      780

ggcgugcugg ccaagagcgu gaagaacauc augcugggcc acgccagcgu gcaggccgag      840

auggagcagg ugguggaggu guacgaguac gcccagaagc ugggcggcga ggccggcuuc      900

uaccacaucc ugaacaaccc caaggccagc cugcugagcc ugacccaguu cccccacuuc      960

agcagcgugg ugcugggcaa cgccgccggc cugggcauca ugggcgagua cagaggcacc     1020

cccagaaacc aggaccugua cgacgccgcc aaggccuacg ccgagcagcu gaaggagaac     1080

ggcgugauca acuacagcgu gcuggaccug accgccgagg agcuggaggc caucaagcac     1140

cagcugaacc ccaaggacaa cgacguggag cuguga                               1176


<210>  10140
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__P03418.1__N

<400>  10140
auggcccuga gcaaggugaa acucaacgac acccugaaua aggaucagcu ucuguccucu       60

agcaaauaca caauccaaag auccacgggc gacucuauug auacccccaa cuaugacguc      120

cagaagcaca ucaauaaacu cugcgggaug cugcuuauua cagaggaugc uaaccauaag      180

uucaccggac ugaucggcau gcucuacgcc augagccggc uggggcgcga agacacaauu      240

aagauccuga gagaugcggg auaucacguu aaagcuaaug gcguggacgu gaccacacau      300

cggcaggaua ucaacgggaa ggagaugaaa uuugaagucc ucacccuggc cucccuuacg      360

accgagauuc agaucaauau ugaaaucgag ucucgcaaga gcuacaaaaa gaugcugaag      420

gagaugggag aaguggcccc ugaguauaga cacgacuccc cggauugugg caugauuauc      480

cucugcauug cugcccuggu uaucacaaaa cuugcugccg gcgaccggag cgggcugacc      540

gcggugaucc gcagagccaa caauguccuc aagaacgaaa ugaaacggua caagggacug      600

cugcccaaag auauugcuaa uucuuucuau gagguguuug agaagcaucc ucacuucauc      660

gacguuuuug ugcacuucgg cauugcccaa uccagcacac gcgggggauc uagagucgaa      720

ggcaucuuug cuggacucuu caugaacgcc uacggggcgg gccaggugau gcugcggugg      780

ggcgugcuug ccaaauccgu caagaauauu augcuggggc augcuagcgu ucaggccgag      840

auggaacagg ugguggaggu cuacgaauau gcucaaaagc ucggaggcga ggccggguuu      900

uaccacaucc ugaacaaucc caaagccucu cuucuguccc ucacccaguu cccucauuuu      960

agcuccgugg uucugggaaa cgcugcgggc cuggggauca ugggagagua ucgcggcacg     1020

cccagaaacc aggaccucua cgaugccgcu aaggccuaug ccgaacagcu gaaagagaau     1080

ggcgugauua acuacucugu ccuugaccug acagcugagg aacucgaagc caucaagcac     1140

caacugaauc cuaaagauaa cgacguggag cuuuga                               1176


<210>  10141
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__P03418.1__N

<400>  10141
auggcacuaa gcaaagucaa auuaaacgac acauuaaaca aagaccaacu cuuaucauca       60

ucaaaauaca caauacaaag aagcaccgga gacaguaucg acacaccaaa cuaugacguc      120

caaaaacaua uaaauaaauu augcggcaug cucuuaauca cagaagacgc caaccauaaa      180

uuuacaggau uaauaggaau guuauaugca augucacgac uagguagaga agacacaaua      240

aaaauacuaa gagacgcagg cuaucacgua aaagcaaaug gaguagacgu aaccacacac      300

agacaagaca uaaauggaaa agaaaugaaa uuugaaguau uaacacuagc aucacuaaca      360

acagaaauac aaaucaacau agaaauagaa ucaagaaaaa gcuacaaaaa aauguuaaaa      420

gaaaugggag aagucgcacc agaauauaga caugauucac cagacugcgg aaugauaaua      480

cuaugcauag cagcccuagu aauuacaaaa cuagcagcag gagacagaag cggauuaaca      540

gcaguaauaa gaagagcaaa caacguacua aaaaacgaaa ugaaaagaua uaaaggauua      600

uuaccaaaag acauagcaaa cucauucuau gaaguauucg aaaaacaccc ccacuuuaua      660

gacgucuucg uacacuucgg aauagcccaa ucauccacaa gaggaggauc aagagucgaa      720

ggaauauucg caggauuauu caugaacgca uauggcgcag gacaaguaau gcuaagaugg      780

ggaguacuag caaaauccgu caaaaacaua augcuaggac acgcaucagu ucaagcagaa      840

auggaacaag uaguagaagu auacgaauac gcccaaaaac uaggaggaga agcaggauuc      900

uaccacauac uaaauaaucc aaaagcauca cuacuaagcc uaacccaauu uccccacuuc      960

ucaaguguag uauuaggaaa ugcagcugga cuaggaauaa ugggagaaua cagaggaaca     1020

ccaagaaacc aagacuuaua cgacgcagca aaagcauacg cagagcaacu uaaagaaaac     1080

ggaguaauaa acuauagcgu acuagacuua acagcagaag aacuggaagc aauaaaacau     1140

caauuaaacc cgaaagacaa ugacguagaa uuauaa                               1176


<210>  10142
<211>  1176
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__P03418.1__N

<400>  10142
auggcacucu cgaaaguaaa acucaacgac acccucaaca aagaccaacu ccuuuccagc       60

uccaaauaca ccauccaacg auccaccgga gacuccaucg acacgcccaa cuacgacguc      120

cagaaacaca ucaacaagcu cugcggaaug cuacuaauca ccgaggacgc caaccacaaa      180

uucacaggac uuauagggau gcucuacgcc augucccgcc ucggacgcga agacacaaua      240

aaaauccuac gagacgccgg cuaccacgua aaggcaaacg gcgucgacgu caccacacac      300

agacaagaca ucaacggaaa ggaaaugaaa uucgaagucc ucacccucgc cagccuaacc      360

accgagaucc aaaucaacau cgaaaucgaa ucacgcaaau ccuacaagaa aaugcucaaa      420

gaaaugggag aagucgcccc cgaauaccgu cacgacucgc ccgacugcgg caugauaauc      480

cuaugcaucg ccgcacucgu cauaaccaaa cucgccgccg gugaccgauc aggacugaca      540

gcagucaucc gccgagcaaa caacgugcuc aaaaacgaaa ugaaacgcua caaaggccua      600

cuccccaaag acaucgccaa cuccuucuac gaagucuucg aaaaacaccc acacuucauc      660

gacgucuucg uccacuucgg caucgcacaa ucaucaacca gaggcggcag ccgcguugaa      720

ggcaucuucg caggacucuu uaugaacgcc uacggcgccg gccaagucau gcuccgcugg      780

ggcguccugg caaaaagcgu caaaaacauc augcuaggcc acgcuagcgu ccaagccgaa      840

auggaacaag ucgucgaagu uuacgaguac gcacaaaaac ucggcggcga agcaggcuuc      900

uaccacaucc uaaacaaccc caaagccucc cugcuaucac ucacccaauu cccccacuuc      960

uccagcgucg uccucggcaa cgccgcagga cuaggcauca ugggagaaua ccgcgggaca     1020

ccgcgcaacc aagaccucua cgacgccgcc aaagccuacg ccgaacaacu caaagaaaac     1080

ggcgucauaa acuacucagu ccucgaccuc accgccgaag aacucgaagc caucaaacac     1140

caacucaacc caaaagacaa cgacgucgaa uuauaa                               1176


<210>  10143
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucuuagca aagucaaguu gaaugauaca cucaacaaag      120

aucaacuucu gucauccagc aaauacacca uccaacggag cacaggagau aguauugaua      180

cuccuaauua ugaugugcag aaacacauca auaaguuaug uggcauguua uuaaucacag      240

aagaugcuaa ucauaaauuc acuggguuaa uagguauguu auaugcgaug ucuagguuag      300

gaagagaaga caccauaaaa auacucagag augcgggaua ucauguaaaa gcaaauggag      360

uagauguaac aacacaucgu caagacauua auggaaaaga aaugaaauuu gaaguguuaa      420

cauuggcaag cuuaacaacu gaaauucaaa ucaacauuga gauagaaucu agaaaauccu      480

acaaaaaaau gcuaaaagaa augggagagg uagcuccaga auacaggcau gacucuccug      540

auugugggau gauaauauua uguauagcag cauuaguaau aacuaaauua gcagcagggg      600

acagaucugg ucuuacagcc gugauuagga gagcuaauaa uguccuaaaa aaugaaauga      660

aacguuacaa aggcuuacua cccaaggaca uagccaacag cuucuaugaa guguuugaaa      720

aacaucccca cuuuauagau guuuuuguuc auuuugguau agcacaaucu ucuaccagag      780

guggcaguag aguugaaggg auuuuugcag gauuguuuau gaaugccuau ggugcagggc      840

aagugauguu acggugggga gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug      900

cuagugugca agcagaaaug gaacaaguug uugagguuua ugaauaugcc caaaaauugg      960

guggugaagc aggauucuac cauauauuga acaacccaaa agcaucauua uuaucuuuga     1020

cucaauuucc ucacuucucc aguguaguau uaggcaaugc ugcuggccua ggcauaaugg     1080

gagaguacag agguacaccg aggaaucaag aucuauauga ugcagcaaag gcauaugcug     1140

aacaacucaa agaaaauggu gugauuaacu acaguguacu agacuugaca gcagaagaac     1200

uagaggcuau caaacaucag cuuaauccaa aagauaauga uguagagcuu ugaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10144
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu caacgacacc cugaacaagg      120

accagcugcu cuccagcucc aaguacacca uccagcgcag caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcugug cgggaugcug cucaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucgggaugcu guacgcgaug agccggcucg      300

gccgcgagga cacgaucaag auccugcggg acgccgggua ccacgugaag gccaacggcg      360

uggacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccucgccuc ccugacgacc gagauccaga ucaacaucga gaucgagagc cggaaguccu      480

acaagaagau gcugaaggag augggggagg uggccccgga guaccgccac gacagccccg      540

acugcggcau gaucauccuc ugcaucgcgg cccuggucau caccaagcug gccgccgggg      600

accgguccgg ccucaccgcg gugauccgcc gggccaacaa cgugcugaag aacgagauga      660

agcgcuacaa ggggcugcuc cccaaggaca ucgccaacag cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagucc agcacgcggg      780

gcgggucccg cgucgagggc aucuucgccg ggcuguucau gaacgcguac ggcgccggcc      840

aggugaugcu gcgguggggc gugcucgcca agagcgucaa gaacaucaug cuggggcacg      900

ccuccgugca ggccgagaug gagcaggucg uggaggugua cgaguacgcg cagaagcucg      960

ggggcgaggc cggguucuac cacauccuga acaacccgaa ggccagccug cugucccuca     1020

cccaguuccc ccacuucagc agcguggucc ugggcaacgc cgccggccug gggaucaugg     1080

gcgaguaccg cgggacgccc cggaaccagg accucuacga cgcggccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acuccgugcu ggaccucacc gccgaggagc     1200

uggaggcgau caagcaccag cugaacccca aggacaacga cgucgagcuc ugaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10145
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10145
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccucucca aggucaagcu caacgacacc cucaacaagg      120

accagcuccu cuccuccucc aaguacacca uccagcgcuc caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcucug cggcaugcuc cucaucaccg      240

aggacgccaa ccacaaguuc accggccuca ucggcaugcu cuacgccaug ucccgccucg      300

gccgcgagga caccaucaag auccuccgcg acgccggcua ccacgucaag gccaacggcg      360

ucgacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gagguccuca      420

cccucgccuc ccucaccacc gagauccaga ucaacaucga gaucgagucc cgcaaguccu      480

acaagaagau gcucaaggag augggcgagg ucgcccccga guaccgccac gacucccccg      540

acugcggcau gaucauccuc ugcaucgccg cccucgucau caccaagcuc gccgccggcg      600

accgcuccgg ccucaccgcc gucauccgcc gcgccaacaa cguccucaag aacgagauga      660

agcgcuacaa gggccuccuc cccaaggaca ucgccaacuc cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac gucuucgucc acuucggcau cgcccagucc uccacccgcg      780

gcggcucccg cgucgagggc aucuucgccg gccucuucau gaacgccuac ggcgccggcc      840

aggucaugcu ccgcuggggc guccucgcca aguccgucaa gaacaucaug cucggccacg      900

ccuccgucca ggccgagaug gagcaggucg ucgaggucua cgaguacgcc cagaagcucg      960

gcggcgaggc cggcuucuac cacauccuca acaaccccaa ggccucccuc cucucccuca     1020

cccaguuccc ccacuucucc uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg     1080

gcgaguaccg cggcaccccc cgcaaccagg accucuacga cgccgccaag gccuacgccg     1140

agcagcucaa ggagaacggc gucaucaacu acuccguccu cgaccucacc gccgaggagc     1200

ucgaggccau caagcaccag cucaacccca aggacaacga cgucgagcuc ugaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10146
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10146
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cuuaauaagg      120

aucagcuguu guccucuuca aaauacacaa uccaaagaag uacuggcgac agcauugaua      180

cgcccaacua ugacguccag aagcacauaa auaaauuaug cgggaugcug cuaaucaccg      240

aggaugcuaa ccauaaguuc acaggacuca uugguaugcu guacgcaaug uccaggcuug      300

gccgggaaga cacuaucaag auucugcgcg augccgggua ucacguuaaa gcgaauggag      360

uggacguaac cacacaucga caggauauca acggcaagga gaugaaauuu gaaguguuga      420

cccucgcuuc ucugacuaca gagauacaga ucaauauuga aaucgagucg cguaagucau      480

acaaaaagau gcugaaggag augggugaag ucgccccuga guauagacac gacagcccag      540

auugugggau gauuauccuc ugcauagcag ccuuagugau uaccaaacug gcugcaggag      600

acaggagugg ccuuacggcc guuauccggc gcgcuaacaa uguguugaag aacgaaauga      660

aaagauacaa gggccugcua ccgaaagaua uugccaauuc cuucuaugag gucuuugaga      720

agcaucccca cuucaucgac guguuuguac acuucgggau cgcgcaaucu agcacuaggg      780

gagguucccg gguugaaggc auuuuugcag gacucuucau gaacgccuac ggggcuggcc      840

aggugaugcu gcgcuggggu guccuugcca aaucagugaa gaauauaaug cuggggcaug      900

caagugugca ggcugagaug gaacaggucg uugaggugua cgaauaugcc caaaaguugg      960

gaggcgaggc gggcuuuuac cacauccuca acaauccuaa agccagccug uuaucucuga     1020

cccaguuccc acauuuuucc ucaguagugc ucgggaacgc agcuggacuu gguauuaugg     1080

gcgaguaucg agggacaccc agaaaccagg accuguacga ugccgcuaag gccuaugcag     1140

aacaguugaa agagaaugga gucaucaacu acagcgugcu agaccugacu gccgaggaac     1200

ucgaagcuau aaagcaccaa cugaauccua aagauaacga cguugagcuu ugaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10147
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10147
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu gaacgacacc cugaacaagg      120

accagcugcu gagcagcagc aaguacacca uccagagaag caccggcgac agcaucgaca      180

cccccaacua cgacgugcag aagcacauca acaagcugug cggcaugcug cugaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucggcaugcu guacgccaug agcagacugg      300

gcagagagga caccaucaag auccugagag acgccggcua ccacgugaag gccaacggcg      360

uggacgugac cacccacaga caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccuggccag ccugaccacc gagauccaga ucaacaucga gaucgagagc agaaagagcu      480

acaagaagau gcugaaggag augggcgagg uggcccccga guacagacac gacagccccg      540

acugcggcau gaucauccug ugcaucgccg cccuggugau caccaagcug gccgccggcg      600

acagaagcgg ccugaccgcc gugaucagaa gagccaacaa cgugcugaag aacgagauga      660

agagauacaa gggccugcug cccaaggaca ucgccaacag cuucuacgag guguucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagagc agcaccagag      780

gcggcagcag aguggagggc aucuucgccg gccuguucau gaacgccuac ggcgccggcc      840

aggugaugcu gagauggggc gugcuggcca agagcgugaa gaacaucaug cugggccacg      900

ccagcgugca ggccgagaug gagcaggugg uggaggugua cgaguacgcc cagaagcugg      960

gcggcgaggc cggcuucuac cacauccuga acaaccccaa ggccagccug cugagccuga     1020

cccaguuccc ccacuucagc agcguggugc ugggcaacgc cgccggccug ggcaucaugg     1080

gcgaguacag aggcaccccc agaaaccagg accuguacga cgccgccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acagcgugcu ggaccugacc gccgaggagc     1200

uggaggccau caagcaccag cugaacccca aggacaacga cguggagcug ugaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10148
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10148
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cugaauaagg      120

aucagcuucu guccucuagc aaauacacaa uccaaagauc cacgggcgac ucuauugaua      180

cccccaacua ugacguccag aagcacauca auaaacucug cgggaugcug cuuauuacag      240

aggaugcuaa ccauaaguuc accggacuga ucggcaugcu cuacgccaug agccggcugg      300

ggcgcgaaga cacaauuaag auccugagag augcgggaua ucacguuaaa gcuaauggcg      360

uggacgugac cacacaucgg caggauauca acgggaagga gaugaaauuu gaaguccuca      420

cccuggccuc ccuuacgacc gagauucaga ucaauauuga aaucgagucu cgcaagagcu      480

acaaaaagau gcugaaggag augggagaag uggccccuga guauagacac gacuccccgg      540

auuguggcau gauuauccuc ugcauugcug cccugguuau cacaaaacuu gcugccggcg      600

accggagcgg gcugaccgcg gugauccgca gagccaacaa uguccucaag aacgaaauga      660

aacgguacaa gggacugcug cccaaagaua uugcuaauuc uuucuaugag guguuugaga      720

agcauccuca cuucaucgac guuuuugugc acuucggcau ugcccaaucc agcacacgcg      780

ggggaucuag agucgaaggc aucuuugcug gacucuucau gaacgccuac ggggcgggcc      840

aggugaugcu gcgguggggc gugcuugcca aauccgucaa gaauauuaug cuggggcaug      900

cuagcguuca ggccgagaug gaacaggugg uggaggucua cgaauaugcu caaaagcucg      960

gaggcgaggc cggguuuuac cacauccuga acaaucccaa agccucucuu cugucccuca     1020

cccaguuccc ucauuuuagc uccgugguuc ugggaaacgc ugcgggccug gggaucaugg     1080

gagaguaucg cggcacgccc agaaaccagg accucuacga ugccgcuaag gccuaugccg     1140

aacagcugaa agagaauggc gugauuaacu acucuguccu ugaccugaca gcugaggaac     1200

ucgaagccau caagcaccaa cugaauccua aagauaacga cguggagcuu ugaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10149
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10149
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaagca aagucaaauu aaacgacaca uuaaacaaag      120

accaacucuu aucaucauca aaauacacaa uacaaagaag caccggagac aguaucgaca      180

caccaaacua ugacguccaa aaacauauaa auaaauuaug cggcaugcuc uuaaucacag      240

aagacgccaa ccauaaauuu acaggauuaa uaggaauguu auaugcaaug ucacgacuag      300

guagagaaga cacaauaaaa auacuaagag acgcaggcua ucacguaaaa gcaaauggag      360

uagacguaac cacacacaga caagacauaa auggaaaaga aaugaaauuu gaaguauuaa      420

cacuagcauc acuaacaaca gaaauacaaa ucaacauaga aauagaauca agaaaaagcu      480

acaaaaaaau guuaaaagaa augggagaag ucgcaccaga auauagacau gauucaccag      540

acugcggaau gauaauacua ugcauagcag cccuaguaau uacaaaacua gcagcaggag      600

acagaagcgg auuaacagca guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga      660

aaagauauaa aggauuauua ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa      720

aacaccccca cuuuauagac gucuucguac acuucggaau agcccaauca uccacaagag      780

gaggaucaag agucgaagga auauucgcag gauuauucau gaacgcauau ggcgcaggac      840

aaguaaugcu aagaugggga guacuagcaa aauccgucaa aaacauaaug cuaggacacg      900

caucaguuca agcagaaaug gaacaaguag uagaaguaua cgaauacgcc caaaaacuag      960

gaggagaagc aggauucuac cacauacuaa auaauccaaa agcaucacua cuaagccuaa     1020

cccaauuucc ccacuucuca aguguaguau uaggaaaugc agcuggacua ggaauaaugg     1080

gagaauacag aggaacacca agaaaccaag acuuauacga cgcagcaaaa gcauacgcag     1140

agcaacuuaa agaaaacgga guaauaaacu auagcguacu agacuuaaca gcagaagaac     1200

uggaagcaau aaaacaucaa uuaaacccga aagacaauga cguagaauua uaaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10150
<211>  1452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10150
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacucucga aaguaaaacu caacgacacc cucaacaaag      120

accaacuccu uuccagcucc aaauacacca uccaacgauc caccggagac uccaucgaca      180

cgcccaacua cgacguccag aaacacauca acaagcucug cggaaugcua cuaaucaccg      240

aggacgccaa ccacaaauuc acaggacuua uagggaugcu cuacgccaug ucccgccucg      300

gacgcgaaga cacaauaaaa auccuacgag acgccggcua ccacguaaag gcaaacggcg      360

ucgacgucac cacacacaga caagacauca acggaaagga aaugaaauuc gaaguccuca      420

cccucgccag ccuaaccacc gagauccaaa ucaacaucga aaucgaauca cgcaaauccu      480

acaagaaaau gcucaaagaa augggagaag ucgcccccga auaccgucac gacucgcccg      540

acugcggcau gauaauccua ugcaucgccg cacucgucau aaccaaacuc gccgccggug      600

accgaucagg acugacagca gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga      660

aacgcuacaa aggccuacuc cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa      720

aacacccaca cuucaucgac gucuucgucc acuucggcau cgcacaauca ucaaccagag      780

gcggcagccg cguugaaggc aucuucgcag gacucuuuau gaacgccuac ggcgccggcc      840

aagucaugcu ccgcuggggc guccuggcaa aaagcgucaa aaacaucaug cuaggccacg      900

cuagcgucca agccgaaaug gaacaagucg ucgaaguuua cgaguacgca caaaaacucg      960

gcggcgaagc aggcuucuac cacauccuaa acaaccccaa agccucccug cuaucacuca     1020

cccaauuccc ccacuucucc agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg     1080

gagaauaccg cgggacaccg cgcaaccaag accucuacga cgccgccaaa gccuacgccg     1140

aacaacucaa agaaaacggc gucauaaacu acucaguccu cgaccucacc gccgaagaac     1200

ucgaagccau caaacaccaa cucaacccaa aagacaacga cgucgaauua uaaggacuag     1260

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1320

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1440

gccaccagaa uu                                                         1452


<210>  10151
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10151
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cucuuagcaa agucaaguug      120

aaugauacac ucaacaaaga ucaacuucug ucauccagca aauacaccau ccaacggagc      180

acaggagaua guauugauac uccuaauuau gaugugcaga aacacaucaa uaaguuaugu      240

ggcauguuau uaaucacaga agaugcuaau cauaaauuca cuggguuaau agguauguua      300

uaugcgaugu cuagguuagg aagagaagac accauaaaaa uacucagaga ugcgggauau      360

cauguaaaag caaauggagu agauguaaca acacaucguc aagacauuaa uggaaaagaa      420

augaaauuug aaguguuaac auuggcaagc uuaacaacug aaauucaaau caacauugag      480

auagaaucua gaaaauccua caaaaaaaug cuaaaagaaa ugggagaggu agcuccagaa      540

uacaggcaug acucuccuga uugugggaug auaauauuau guauagcagc auuaguaaua      600

acuaaauuag cagcagggga cagaucuggu cuuacagccg ugauuaggag agcuaauaau      660

guccuaaaaa augaaaugaa acguuacaaa ggcuuacuac ccaaggacau agccaacagc      720

uucuaugaag uguuugaaaa acauccccac uuuauagaug uuuuuguuca uuuugguaua      780

gcacaaucuu cuaccagagg uggcaguaga guugaaggga uuuuugcagg auuguuuaug      840

aaugccuaug gugcagggca agugauguua cgguggggag ucuuagcaaa aucaguuaaa      900

aauauuaugu uaggacaugc uagugugcaa gcagaaaugg aacaaguugu ugagguuuau      960

gaauaugccc aaaaauuggg uggugaagca ggauucuacc auauauugaa caacccaaaa     1020

gcaucauuau uaucuuugac ucaauuuccu cacuucucca guguaguauu aggcaaugcu     1080

gcuggccuag gcauaauggg agaguacaga gguacaccga ggaaucaaga ucuauaugau     1140

gcagcaaagg cauaugcuga acaacucaaa gaaaauggug ugauuaacua caguguacua     1200

gacuugacag cagaagaacu agaggcuauc aaacaucagc uuaauccaaa agauaaugau     1260

guagagcuuu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10152
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10152
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcuc      120

aacgacaccc ugaacaagga ccagcugcuc uccagcucca aguacaccau ccagcgcagc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcugugc      240

gggaugcugc ucaucaccga ggacgccaac cacaaguuca ccggccugau cgggaugcug      300

uacgcgauga gccggcucgg ccgcgaggac acgaucaaga uccugcggga cgccggguac      360

cacgugaagg ccaacggcgu ggacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccucgccucc cugacgaccg agauccagau caacaucgag      480

aucgagagcc ggaaguccua caagaagaug cugaaggaga ugggggaggu ggccccggag      540

uaccgccacg acagccccga cugcggcaug aucauccucu gcaucgcggc ccuggucauc      600

accaagcugg ccgccgggga ccgguccggc cucaccgcgg ugauccgccg ggccaacaac      660

gugcugaaga acgagaugaa gcgcuacaag gggcugcucc ccaaggacau cgccaacagc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagucca gcacgcgggg cgggucccgc gucgagggca ucuucgccgg gcuguucaug      840

aacgcguacg gcgccggcca ggugaugcug cgguggggcg ugcucgccaa gagcgucaag      900

aacaucaugc uggggcacgc cuccgugcag gccgagaugg agcaggucgu ggagguguac      960

gaguacgcgc agaagcucgg gggcgaggcc ggguucuacc acauccugaa caacccgaag     1020

gccagccugc ugucccucac ccaguucccc cacuucagca gcgugguccu gggcaacgcc     1080

gccggccugg ggaucauggg cgaguaccgc gggacgcccc ggaaccagga ccucuacgac     1140

gcggccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cuccgugcug     1200

gaccucaccg ccgaggagcu ggaggcgauc aagcaccagc ugaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10153
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10153
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccucuccaa ggucaagcuc      120

aacgacaccc ucaacaagga ccagcuccuc uccuccucca aguacaccau ccagcgcucc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcucugc      240

ggcaugcucc ucaucaccga ggacgccaac cacaaguuca ccggccucau cggcaugcuc      300

uacgccaugu cccgccucgg ccgcgaggac accaucaaga uccuccgcga cgccggcuac      360

cacgucaagg ccaacggcgu cgacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg agguccucac ccucgccucc cucaccaccg agauccagau caacaucgag      480

aucgaguccc gcaaguccua caagaagaug cucaaggaga ugggcgaggu cgcccccgag      540

uaccgccacg acucccccga cugcggcaug aucauccucu gcaucgccgc ccucgucauc      600

accaagcucg ccgccggcga ccgcuccggc cucaccgccg ucauccgccg cgccaacaac      660

guccucaaga acgagaugaa gcgcuacaag ggccuccucc ccaaggacau cgccaacucc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg ucuucgucca cuucggcauc      780

gcccaguccu ccacccgcgg cggcucccgc gucgagggca ucuucgccgg ccucuucaug      840

aacgccuacg gcgccggcca ggucaugcuc cgcuggggcg uccucgccaa guccgucaag      900

aacaucaugc ucggccacgc cuccguccag gccgagaugg agcaggucgu cgaggucuac      960

gaguacgccc agaagcucgg cggcgaggcc ggcuucuacc acauccucaa caaccccaag     1020

gccucccucc ucucccucac ccaguucccc cacuucuccu ccgucguccu cggcaacgcc     1080

gccggccucg gcaucauggg cgaguaccgc ggcacccccc gcaaccagga ccucuacgac     1140

gccgccaagg ccuacgccga gcagcucaag gagaacggcg ucaucaacua cuccguccuc     1200

gaccucaccg ccgaggagcu cgaggccauc aagcaccagc ucaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10154
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10154
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc uuaauaagga ucagcuguug uccucuucaa aauacacaau ccaaagaagu      180

acuggcgaca gcauugauac gcccaacuau gacguccaga agcacauaaa uaaauuaugc      240

gggaugcugc uaaucaccga ggaugcuaac cauaaguuca caggacucau ugguaugcug      300

uacgcaaugu ccaggcuugg ccgggaagac acuaucaaga uucugcgcga ugccggguau      360

cacguuaaag cgaauggagu ggacguaacc acacaucgac aggauaucaa cggcaaggag      420

augaaauuug aaguguugac ccucgcuucu cugacuacag agauacagau caauauugaa      480

aucgagucgc guaagucaua caaaaagaug cugaaggaga ugggugaagu cgccccugag      540

uauagacacg acagcccaga uugugggaug auuauccucu gcauagcagc cuuagugauu      600

accaaacugg cugcaggaga caggaguggc cuuacggccg uuauccggcg cgcuaacaau      660

guguugaaga acgaaaugaa aagauacaag ggccugcuac cgaaagauau ugccaauucc      720

uucuaugagg ucuuugagaa gcauccccac uucaucgacg uguuuguaca cuucgggauc      780

gcgcaaucua gcacuagggg agguucccgg guugaaggca uuuuugcagg acucuucaug      840

aacgccuacg gggcuggcca ggugaugcug cgcuggggug uccuugccaa aucagugaag      900

aauauaaugc uggggcaugc aagugugcag gcugagaugg aacaggucgu ugagguguac      960

gaauaugccc aaaaguuggg aggcgaggcg ggcuuuuacc acauccucaa caauccuaaa     1020

gccagccugu uaucucugac ccaguuccca cauuuuuccu caguagugcu cgggaacgca     1080

gcuggacuug guauuauggg cgaguaucga gggacaccca gaaaccagga ccuguacgau     1140

gccgcuaagg ccuaugcaga acaguugaaa gagaauggag ucaucaacua cagcgugcua     1200

gaccugacug ccgaggaacu cgaagcuaua aagcaccaac ugaauccuaa agauaacgac     1260

guugagcuuu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10155
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10155
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcug      120

aacgacaccc ugaacaagga ccagcugcug agcagcagca aguacaccau ccagagaagc      180

accggcgaca gcaucgacac ccccaacuac gacgugcaga agcacaucaa caagcugugc      240

ggcaugcugc ugaucaccga ggacgccaac cacaaguuca ccggccugau cggcaugcug      300

uacgccauga gcagacuggg cagagaggac accaucaaga uccugagaga cgccggcuac      360

cacgugaagg ccaacggcgu ggacgugacc acccacagac aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccuggccagc cugaccaccg agauccagau caacaucgag      480

aucgagagca gaaagagcua caagaagaug cugaaggaga ugggcgaggu ggcccccgag      540

uacagacacg acagccccga cugcggcaug aucauccugu gcaucgccgc ccuggugauc      600

accaagcugg ccgccggcga cagaagcggc cugaccgccg ugaucagaag agccaacaac      660

gugcugaaga acgagaugaa gagauacaag ggccugcugc ccaaggacau cgccaacagc      720

uucuacgagg uguucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagagca gcaccagagg cggcagcaga guggagggca ucuucgccgg ccuguucaug      840

aacgccuacg gcgccggcca ggugaugcug agauggggcg ugcuggccaa gagcgugaag      900

aacaucaugc ugggccacgc cagcgugcag gccgagaugg agcagguggu ggagguguac      960

gaguacgccc agaagcuggg cggcgaggcc ggcuucuacc acauccugaa caaccccaag     1020

gccagccugc ugagccugac ccaguucccc cacuucagca gcguggugcu gggcaacgcc     1080

gccggccugg gcaucauggg cgaguacaga ggcaccccca gaaaccagga ccuguacgac     1140

gccgccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cagcgugcug     1200

gaccugaccg ccgaggagcu ggaggccauc aagcaccagc ugaaccccaa ggacaacgac     1260

guggagcugu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10156
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10156
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc ugaauaagga ucagcuucug uccucuagca aauacacaau ccaaagaucc      180

acgggcgacu cuauugauac ccccaacuau gacguccaga agcacaucaa uaaacucugc      240

gggaugcugc uuauuacaga ggaugcuaac cauaaguuca ccggacugau cggcaugcuc      300

uacgccauga gccggcuggg gcgcgaagac acaauuaaga uccugagaga ugcgggauau      360

cacguuaaag cuaauggcgu ggacgugacc acacaucggc aggauaucaa cgggaaggag      420

augaaauuug aaguccucac ccuggccucc cuuacgaccg agauucagau caauauugaa      480

aucgagucuc gcaagagcua caaaaagaug cugaaggaga ugggagaagu ggccccugag      540

uauagacacg acuccccgga uuguggcaug auuauccucu gcauugcugc ccugguuauc      600

acaaaacuug cugccggcga ccggagcggg cugaccgcgg ugauccgcag agccaacaau      660

guccucaaga acgaaaugaa acgguacaag ggacugcugc ccaaagauau ugcuaauucu      720

uucuaugagg uguuugagaa gcauccucac uucaucgacg uuuuugugca cuucggcauu      780

gcccaaucca gcacacgcgg gggaucuaga gucgaaggca ucuuugcugg acucuucaug      840

aacgccuacg gggcgggcca ggugaugcug cgguggggcg ugcuugccaa auccgucaag      900

aauauuaugc uggggcaugc uagcguucag gccgagaugg aacagguggu ggaggucuac      960

gaauaugcuc aaaagcucgg aggcgaggcc ggguuuuacc acauccugaa caaucccaaa     1020

gccucucuuc ugucccucac ccaguucccu cauuuuagcu ccgugguucu gggaaacgcu     1080

gcgggccugg ggaucauggg agaguaucgc ggcacgccca gaaaccagga ccucuacgau     1140

gccgcuaagg ccuaugccga acagcugaaa gagaauggcg ugauuaacua cucuguccuu     1200

gaccugacag cugaggaacu cgaagccauc aagcaccaac ugaauccuaa agauaacgac     1260

guggagcuuu gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10157
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10157
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacuaagcaa agucaaauua      120

aacgacacau uaaacaaaga ccaacucuua ucaucaucaa aauacacaau acaaagaagc      180

accggagaca guaucgacac accaaacuau gacguccaaa aacauauaaa uaaauuaugc      240

ggcaugcucu uaaucacaga agacgccaac cauaaauuua caggauuaau aggaauguua      300

uaugcaaugu cacgacuagg uagagaagac acaauaaaaa uacuaagaga cgcaggcuau      360

cacguaaaag caaauggagu agacguaacc acacacagac aagacauaaa uggaaaagaa      420

augaaauuug aaguauuaac acuagcauca cuaacaacag aaauacaaau caacauagaa      480

auagaaucaa gaaaaagcua caaaaaaaug uuaaaagaaa ugggagaagu cgcaccagaa      540

uauagacaug auucaccaga cugcggaaug auaauacuau gcauagcagc ccuaguaauu      600

acaaaacuag cagcaggaga cagaagcgga uuaacagcag uaauaagaag agcaaacaac      660

guacuaaaaa acgaaaugaa aagauauaaa ggauuauuac caaaagacau agcaaacuca      720

uucuaugaag uauucgaaaa acacccccac uuuauagacg ucuucguaca cuucggaaua      780

gcccaaucau ccacaagagg aggaucaaga gucgaaggaa uauucgcagg auuauucaug      840

aacgcauaug gcgcaggaca aguaaugcua agauggggag uacuagcaaa auccgucaaa      900

aacauaaugc uaggacacgc aucaguucaa gcagaaaugg aacaaguagu agaaguauac      960

gaauacgccc aaaaacuagg aggagaagca ggauucuacc acauacuaaa uaauccaaaa     1020

gcaucacuac uaagccuaac ccaauuuccc cacuucucaa guguaguauu aggaaaugca     1080

gcuggacuag gaauaauggg agaauacaga ggaacaccaa gaaaccaaga cuuauacgac     1140

gcagcaaaag cauacgcaga gcaacuuaaa gaaaacggag uaauaaacua uagcguacua     1200

gacuuaacag cagaagaacu ggaagcaaua aaacaucaau uaaacccgaa agacaaugac     1260

guagaauuau aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10158
<211>  1471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10158
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacucucgaa aguaaaacuc      120

aacgacaccc ucaacaaaga ccaacuccuu uccagcucca aauacaccau ccaacgaucc      180

accggagacu ccaucgacac gcccaacuac gacguccaga aacacaucaa caagcucugc      240

ggaaugcuac uaaucaccga ggacgccaac cacaaauuca caggacuuau agggaugcuc      300

uacgccaugu cccgccucgg acgcgaagac acaauaaaaa uccuacgaga cgccggcuac      360

cacguaaagg caaacggcgu cgacgucacc acacacagac aagacaucaa cggaaaggaa      420

augaaauucg aaguccucac ccucgccagc cuaaccaccg agauccaaau caacaucgaa      480

aucgaaucac gcaaauccua caagaaaaug cucaaagaaa ugggagaagu cgcccccgaa      540

uaccgucacg acucgcccga cugcggcaug auaauccuau gcaucgccgc acucgucaua      600

accaaacucg ccgccgguga ccgaucagga cugacagcag ucauccgccg agcaaacaac      660

gugcucaaaa acgaaaugaa acgcuacaaa ggccuacucc ccaaagacau cgccaacucc      720

uucuacgaag ucuucgaaaa acacccacac uucaucgacg ucuucgucca cuucggcauc      780

gcacaaucau caaccagagg cggcagccgc guugaaggca ucuucgcagg acucuuuaug      840

aacgccuacg gcgccggcca agucaugcuc cgcuggggcg uccuggcaaa aagcgucaaa      900

aacaucaugc uaggccacgc uagcguccaa gccgaaaugg aacaagucgu cgaaguuuac      960

gaguacgcac aaaaacucgg cggcgaagca ggcuucuacc acauccuaaa caaccccaaa     1020

gccucccugc uaucacucac ccaauucccc cacuucucca gcgucguccu cggcaacgcc     1080

gcaggacuag gcaucauggg agaauaccgc gggacaccgc gcaaccaaga ccucuacgac     1140

gccgccaaag ccuacgccga acaacucaaa gaaaacggcg ucauaaacua cucaguccuc     1200

gaccucaccg ccgaagaacu cgaagccauc aaacaccaac ucaacccaaa agacaacgac     1260

gucgaauuau aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau     1320

aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     1440

cccaaaggcu cuuuucagag ccaccagaau u                                    1471


<210>  10159
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10159
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcu      180

cuuagcaaag ucaaguugaa ugauacacuc aacaaagauc aacuucuguc auccagcaaa      240

uacaccaucc aacggagcac aggagauagu auugauacuc cuaauuauga ugugcagaaa      300

cacaucaaua aguuaugugg cauguuauua aucacagaag augcuaauca uaaauucacu      360

ggguuaauag guauguuaua ugcgaugucu agguuaggaa gagaagacac cauaaaaaua      420

cucagagaug cgggauauca uguaaaagca aauggaguag auguaacaac acaucgucaa      480

gacauuaaug gaaaagaaau gaaauuugaa guguuaacau uggcaagcuu aacaacugaa      540

auucaaauca acauugagau agaaucuaga aaauccuaca aaaaaaugcu aaaagaaaug      600

ggagagguag cuccagaaua caggcaugac ucuccugauu gugggaugau aauauuaugu      660

auagcagcau uaguaauaac uaaauuagca gcaggggaca gaucuggucu uacagccgug      720

auuaggagag cuaauaaugu ccuaaaaaau gaaaugaaac guuacaaagg cuuacuaccc      780

aaggacauag ccaacagcuu cuaugaagug uuugaaaaac auccccacuu uauagauguu      840

uuuguucauu uugguauagc acaaucuucu accagaggug gcaguagagu ugaagggauu      900

uuugcaggau uguuuaugaa ugccuauggu gcagggcaag ugauguuacg guggggaguc      960

uuagcaaaau caguuaaaaa uauuauguua ggacaugcua gugugcaagc agaaauggaa     1020

caaguuguug agguuuauga auaugcccaa aaauugggug gugaagcagg auucuaccau     1080

auauugaaca acccaaaagc aucauuauua ucuuugacuc aauuuccuca cuucuccagu     1140

guaguauuag gcaaugcugc uggccuaggc auaaugggag aguacagagg uacaccgagg     1200

aaucaagauc uauaugaugc agcaaaggca uaugcugaac aacucaaaga aaauggugug     1260

auuaacuaca guguacuaga cuugacagca gaagaacuag aggcuaucaa acaucagcuu     1320

aauccaaaag auaaugaugu agagcuuuga ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10160
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10160
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcucaa cgacacccug aacaaggacc agcugcucuc cagcuccaag      240

uacaccaucc agcgcagcac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcugugcgg gaugcugcuc aucaccgagg acgccaacca caaguucacc      360

ggccugaucg ggaugcugua cgcgaugagc cggcucggcc gcgaggacac gaucaagauc      420

cugcgggacg ccggguacca cgugaaggcc aacggcgugg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc ucgccucccu gacgaccgag      540

auccagauca acaucgagau cgagagccgg aaguccuaca agaagaugcu gaaggagaug      600

ggggaggugg ccccggagua ccgccacgac agccccgacu gcggcaugau cauccucugc      660

aucgcggccc uggucaucac caagcuggcc gccggggacc gguccggccu caccgcggug      720

auccgccggg ccaacaacgu gcugaagaac gagaugaagc gcuacaaggg gcugcucccc      780

aaggacaucg ccaacagcuu cuacgagguc uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccaguccagc acgcggggcg ggucccgcgu cgagggcauc      900

uucgccgggc uguucaugaa cgcguacggc gccggccagg ugaugcugcg guggggcgug      960

cucgccaaga gcgucaagaa caucaugcug gggcacgccu ccgugcaggc cgagauggag     1020

caggucgugg agguguacga guacgcgcag aagcucgggg gcgaggccgg guucuaccac     1080

auccugaaca acccgaaggc cagccugcug ucccucaccc aguuccccca cuucagcagc     1140

gugguccugg gcaacgccgc cggccugggg aucaugggcg aguaccgcgg gacgccccgg     1200

aaccaggacc ucuacgacgc ggccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuacu ccgugcugga ccucaccgcc gaggagcugg aggcgaucaa gcaccagcug     1320

aaccccaagg acaacgacgu cgagcucuga ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10161
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10161
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cucuccaagg ucaagcucaa cgacacccuc aacaaggacc agcuccucuc cuccuccaag      240

uacaccaucc agcgcuccac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcucugcgg caugcuccuc aucaccgagg acgccaacca caaguucacc      360

ggccucaucg gcaugcucua cgccaugucc cgccucggcc gcgaggacac caucaagauc      420

cuccgcgacg ccggcuacca cgucaaggcc aacggcgucg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag guccucaccc ucgccucccu caccaccgag      540

auccagauca acaucgagau cgagucccgc aaguccuaca agaagaugcu caaggagaug      600

ggcgaggucg cccccgagua ccgccacgac ucccccgacu gcggcaugau cauccucugc      660

aucgccgccc ucgucaucac caagcucgcc gccggcgacc gcuccggccu caccgccguc      720

auccgccgcg ccaacaacgu ccucaagaac gagaugaagc gcuacaaggg ccuccucccc      780

aaggacaucg ccaacuccuu cuacgagguc uucgagaagc acccccacuu caucgacguc      840

uucguccacu ucggcaucgc ccaguccucc acccgcggcg gcucccgcgu cgagggcauc      900

uucgccggcc ucuucaugaa cgccuacggc gccggccagg ucaugcuccg cuggggcguc      960

cucgccaagu ccgucaagaa caucaugcuc ggccacgccu ccguccaggc cgagauggag     1020

caggucgucg aggucuacga guacgcccag aagcucggcg gcgaggccgg cuucuaccac     1080

auccucaaca accccaaggc cucccuccuc ucccucaccc aguuccccca cuucuccucc     1140

gucguccucg gcaacgccgc cggccucggc aucaugggcg aguaccgcgg caccccccgc     1200

aaccaggacc ucuacgacgc cgccaaggcc uacgccgagc agcucaagga gaacggcguc     1260

aucaacuacu ccguccucga ccucaccgcc gaggagcucg aggccaucaa gcaccagcuc     1320

aaccccaagg acaacgacgu cgagcucuga ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10162
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10162
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccuu aauaaggauc agcuguuguc cucuucaaaa      240

uacacaaucc aaagaaguac uggcgacagc auugauacgc ccaacuauga cguccagaag      300

cacauaaaua aauuaugcgg gaugcugcua aucaccgagg augcuaacca uaaguucaca      360

ggacucauug guaugcugua cgcaaugucc aggcuuggcc gggaagacac uaucaagauu      420

cugcgcgaug ccggguauca cguuaaagcg aauggagugg acguaaccac acaucgacag      480

gauaucaacg gcaaggagau gaaauuugaa guguugaccc ucgcuucucu gacuacagag      540

auacagauca auauugaaau cgagucgcgu aagucauaca aaaagaugcu gaaggagaug      600

ggugaagucg ccccugagua uagacacgac agcccagauu gugggaugau uauccucugc      660

auagcagccu uagugauuac caaacuggcu gcaggagaca ggaguggccu uacggccguu      720

auccggcgcg cuaacaaugu guugaagaac gaaaugaaaa gauacaaggg ccugcuaccg      780

aaagauauug ccaauuccuu cuaugagguc uuugagaagc auccccacuu caucgacgug      840

uuuguacacu ucgggaucgc gcaaucuagc acuaggggag guucccgggu ugaaggcauu      900

uuugcaggac ucuucaugaa cgccuacggg gcuggccagg ugaugcugcg cugggguguc      960

cuugccaaau cagugaagaa uauaaugcug gggcaugcaa gugugcaggc ugagauggaa     1020

caggucguug agguguacga auaugcccaa aaguugggag gcgaggcggg cuuuuaccac     1080

auccucaaca auccuaaagc cagccuguua ucucugaccc aguucccaca uuuuuccuca     1140

guagugcucg ggaacgcagc uggacuuggu auuaugggcg aguaucgagg gacacccaga     1200

aaccaggacc uguacgaugc cgcuaaggcc uaugcagaac aguugaaaga gaauggaguc     1260

aucaacuaca gcgugcuaga ccugacugcc gaggaacucg aagcuauaaa gcaccaacug     1320

aauccuaaag auaacgacgu ugagcuuuga ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10163
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10163
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcugaa cgacacccug aacaaggacc agcugcugag cagcagcaag      240

uacaccaucc agagaagcac cggcgacagc aucgacaccc ccaacuacga cgugcagaag      300

cacaucaaca agcugugcgg caugcugcug aucaccgagg acgccaacca caaguucacc      360

ggccugaucg gcaugcugua cgccaugagc agacugggca gagaggacac caucaagauc      420

cugagagacg ccggcuacca cgugaaggcc aacggcgugg acgugaccac ccacagacag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc uggccagccu gaccaccgag      540

auccagauca acaucgagau cgagagcaga aagagcuaca agaagaugcu gaaggagaug      600

ggcgaggugg cccccgagua cagacacgac agccccgacu gcggcaugau cauccugugc      660

aucgccgccc uggugaucac caagcuggcc gccggcgaca gaagcggccu gaccgccgug      720

aucagaagag ccaacaacgu gcugaagaac gagaugaaga gauacaaggg ccugcugccc      780

aaggacaucg ccaacagcuu cuacgaggug uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccagagcagc accagaggcg gcagcagagu ggagggcauc      900

uucgccggcc uguucaugaa cgccuacggc gccggccagg ugaugcugag auggggcgug      960

cuggccaaga gcgugaagaa caucaugcug ggccacgcca gcgugcaggc cgagauggag     1020

cagguggugg agguguacga guacgcccag aagcugggcg gcgaggccgg cuucuaccac     1080

auccugaaca accccaaggc cagccugcug agccugaccc aguuccccca cuucagcagc     1140

guggugcugg gcaacgccgc cggccugggc aucaugggcg aguacagagg cacccccaga     1200

aaccaggacc uguacgacgc cgccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuaca gcgugcugga ccugaccgcc gaggagcugg aggccaucaa gcaccagcug     1320

aaccccaagg acaacgacgu ggagcuguga ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10164
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10164
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccug aauaaggauc agcuucuguc cucuagcaaa      240

uacacaaucc aaagauccac gggcgacucu auugauaccc ccaacuauga cguccagaag      300

cacaucaaua aacucugcgg gaugcugcuu auuacagagg augcuaacca uaaguucacc      360

ggacugaucg gcaugcucua cgccaugagc cggcuggggc gcgaagacac aauuaagauc      420

cugagagaug cgggauauca cguuaaagcu aauggcgugg acgugaccac acaucggcag      480

gauaucaacg ggaaggagau gaaauuugaa guccucaccc uggccucccu uacgaccgag      540

auucagauca auauugaaau cgagucucgc aagagcuaca aaaagaugcu gaaggagaug      600

ggagaagugg ccccugagua uagacacgac uccccggauu guggcaugau uauccucugc      660

auugcugccc ugguuaucac aaaacuugcu gccggcgacc ggagcgggcu gaccgcggug      720

auccgcagag ccaacaaugu ccucaagaac gaaaugaaac gguacaaggg acugcugccc      780

aaagauauug cuaauucuuu cuaugaggug uuugagaagc auccucacuu caucgacguu      840

uuugugcacu ucggcauugc ccaauccagc acacgcgggg gaucuagagu cgaaggcauc      900

uuugcuggac ucuucaugaa cgccuacggg gcgggccagg ugaugcugcg guggggcgug      960

cuugccaaau ccgucaagaa uauuaugcug gggcaugcua gcguucaggc cgagauggaa     1020

cagguggugg aggucuacga auaugcucaa aagcucggag gcgaggccgg guuuuaccac     1080

auccugaaca aucccaaagc cucucuucug ucccucaccc aguucccuca uuuuagcucc     1140

gugguucugg gaaacgcugc gggccugggg aucaugggag aguaucgcgg cacgcccaga     1200

aaccaggacc ucuacgaugc cgcuaaggcc uaugccgaac agcugaaaga gaauggcgug     1260

auuaacuacu cuguccuuga ccugacagcu gaggaacucg aagccaucaa gcaccaacug     1320

aauccuaaag auaacgacgu ggagcuuuga ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10165
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10165
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cuaagcaaag ucaaauuaaa cgacacauua aacaaagacc aacucuuauc aucaucaaaa      240

uacacaauac aaagaagcac cggagacagu aucgacacac caaacuauga cguccaaaaa      300

cauauaaaua aauuaugcgg caugcucuua aucacagaag acgccaacca uaaauuuaca      360

ggauuaauag gaauguuaua ugcaauguca cgacuaggua gagaagacac aauaaaaaua      420

cuaagagacg caggcuauca cguaaaagca aauggaguag acguaaccac acacagacaa      480

gacauaaaug gaaaagaaau gaaauuugaa guauuaacac uagcaucacu aacaacagaa      540

auacaaauca acauagaaau agaaucaaga aaaagcuaca aaaaaauguu aaaagaaaug      600

ggagaagucg caccagaaua uagacaugau ucaccagacu gcggaaugau aauacuaugc      660

auagcagccc uaguaauuac aaaacuagca gcaggagaca gaagcggauu aacagcagua      720

auaagaagag caaacaacgu acuaaaaaac gaaaugaaaa gauauaaagg auuauuacca      780

aaagacauag caaacucauu cuaugaagua uucgaaaaac acccccacuu uauagacguc      840

uucguacacu ucggaauagc ccaaucaucc acaagaggag gaucaagagu cgaaggaaua      900

uucgcaggau uauucaugaa cgcauauggc gcaggacaag uaaugcuaag auggggagua      960

cuagcaaaau ccgucaaaaa cauaaugcua ggacacgcau caguucaagc agaaauggaa     1020

caaguaguag aaguauacga auacgcccaa aaacuaggag gagaagcagg auucuaccac     1080

auacuaaaua auccaaaagc aucacuacua agccuaaccc aauuucccca cuucucaagu     1140

guaguauuag gaaaugcagc uggacuagga auaaugggag aauacagagg aacaccaaga     1200

aaccaagacu uauacgacgc agcaaaagca uacgcagagc aacuuaaaga aaacggagua     1260

auaaacuaua gcguacuaga cuuaacagca gaagaacugg aagcaauaaa acaucaauua     1320

aacccgaaag acaaugacgu agaauuauaa ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10166
<211>  1549
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10166
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cucucgaaag uaaaacucaa cgacacccuc aacaaagacc aacuccuuuc cagcuccaaa      240

uacaccaucc aacgauccac cggagacucc aucgacacgc ccaacuacga cguccagaaa      300

cacaucaaca agcucugcgg aaugcuacua aucaccgagg acgccaacca caaauucaca      360

ggacuuauag ggaugcucua cgccaugucc cgccucggac gcgaagacac aauaaaaauc      420

cuacgagacg ccggcuacca cguaaaggca aacggcgucg acgucaccac acacagacaa      480

gacaucaacg gaaaggaaau gaaauucgaa guccucaccc ucgccagccu aaccaccgag      540

auccaaauca acaucgaaau cgaaucacgc aaauccuaca agaaaaugcu caaagaaaug      600

ggagaagucg cccccgaaua ccgucacgac ucgcccgacu gcggcaugau aauccuaugc      660

aucgccgcac ucgucauaac caaacucgcc gccggugacc gaucaggacu gacagcaguc      720

auccgccgag caaacaacgu gcucaaaaac gaaaugaaac gcuacaaagg ccuacucccc      780

aaagacaucg ccaacuccuu cuacgaaguc uucgaaaaac acccacacuu caucgacguc      840

uucguccacu ucggcaucgc acaaucauca accagaggcg gcagccgcgu ugaaggcauc      900

uucgcaggac ucuuuaugaa cgccuacggc gccggccaag ucaugcuccg cuggggcguc      960

cuggcaaaaa gcgucaaaaa caucaugcua ggccacgcua gcguccaagc cgaaauggaa     1020

caagucgucg aaguuuacga guacgcacaa aaacucggcg gcgaagcagg cuucuaccac     1080

auccuaaaca accccaaagc cucccugcua ucacucaccc aauuccccca cuucuccagc     1140

gucguccucg gcaacgccgc aggacuaggc aucaugggag aauaccgcgg gacaccgcgc     1200

aaccaagacc ucuacgacgc cgccaaagcc uacgccgaac aacucaaaga aaacggcguc     1260

auaaacuacu caguccucga ccucaccgcc gaagaacucg aagccaucaa acaccaacuc     1320

aacccaaaag acaacgacgu cgaauuauaa ggacuagucc cuguucccag agcccacuuu     1380

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1500

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1549


<210>  10167
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10167
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcuc uuagcaaagu caaguugaau gauacacuca acaaagauca acuucuguca      180

uccagcaaau acaccaucca acggagcaca ggagauagua uugauacucc uaauuaugau      240

gugcagaaac acaucaauaa guuauguggc auguuauuaa ucacagaaga ugcuaaucau      300

aaauucacug gguuaauagg uauguuauau gcgaugucua gguuaggaag agaagacacc      360

auaaaaauac ucagagaugc gggauaucau guaaaagcaa auggaguaga uguaacaaca      420

caucgucaag acauuaaugg aaaagaaaug aaauuugaag uguuaacauu ggcaagcuua      480

acaacugaaa uucaaaucaa cauugagaua gaaucuagaa aauccuacaa aaaaaugcua      540

aaagaaaugg gagagguagc uccagaauac aggcaugacu cuccugauug ugggaugaua      600

auauuaugua uagcagcauu aguaauaacu aaauuagcag caggggacag aucuggucuu      660

acagccguga uuaggagagc uaauaauguc cuaaaaaaug aaaugaaacg uuacaaaggc      720

uuacuaccca aggacauagc caacagcuuc uaugaagugu uugaaaaaca uccccacuuu      780

auagauguuu uuguucauuu ugguauagca caaucuucua ccagaggugg caguagaguu      840

gaagggauuu uugcaggauu guuuaugaau gccuauggug cagggcaagu gauguuacgg      900

uggggagucu uagcaaaauc aguuaaaaau auuauguuag gacaugcuag ugugcaagca      960

gaaauggaac aaguuguuga gguuuaugaa uaugcccaaa aauugggugg ugaagcagga     1020

uucuaccaua uauugaacaa cccaaaagca ucauuauuau cuuugacuca auuuccucac     1080

uucuccagug uaguauuagg caaugcugcu ggccuaggca uaaugggaga guacagaggu     1140

acaccgagga aucaagaucu auaugaugca gcaaaggcau augcugaaca acucaaagaa     1200

aaugguguga uuaacuacag uguacuagac uugacagcag aagaacuaga ggcuaucaaa     1260

caucagcuua auccaaaaga uaaugaugua gagcuuugag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10168
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10168
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcucaac gacacccuga acaaggacca gcugcucucc      180

agcuccaagu acaccaucca gcgcagcacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcugugcggg augcugcuca ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg gaugcuguac gcgaugagcc ggcucggccg cgaggacacg      360

aucaagaucc ugcgggacgc cggguaccac gugaaggcca acggcgugga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg ugcugacccu cgccucccug      480

acgaccgaga uccagaucaa caucgagauc gagagccgga aguccuacaa gaagaugcug      540

aaggagaugg gggagguggc cccggaguac cgccacgaca gccccgacug cggcaugauc      600

auccucugca ucgcggcccu ggucaucacc aagcuggccg ccggggaccg guccggccuc      660

accgcgguga uccgccgggc caacaacgug cugaagaacg agaugaagcg cuacaagggg      720

cugcucccca aggacaucgc caacagcuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc caguccagca cgcggggcgg gucccgcguc      840

gagggcaucu ucgccgggcu guucaugaac gcguacggcg ccggccaggu gaugcugcgg      900

uggggcgugc ucgccaagag cgucaagaac aucaugcugg ggcacgccuc cgugcaggcc      960

gagauggagc aggucgugga gguguacgag uacgcgcaga agcucggggg cgaggccggg     1020

uucuaccaca uccugaacaa cccgaaggcc agccugcugu cccucaccca guucccccac     1080

uucagcagcg ugguccuggg caacgccgcc ggccugggga ucaugggcga guaccgcggg     1140

acgccccgga accaggaccu cuacgacgcg gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacuc cgugcuggac cucaccgccg aggagcugga ggcgaucaag     1260

caccagcuga accccaagga caacgacguc gagcucugag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10169
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10169
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ucuccaaggu caagcucaac gacacccuca acaaggacca gcuccucucc      180

uccuccaagu acaccaucca gcgcuccacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcucugcggc augcuccuca ucaccgagga cgccaaccac      300

aaguucaccg gccucaucgg caugcucuac gccauguccc gccucggccg cgaggacacc      360

aucaagaucc uccgcgacgc cggcuaccac gucaaggcca acggcgucga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg uccucacccu cgccucccuc      480

accaccgaga uccagaucaa caucgagauc gagucccgca aguccuacaa gaagaugcuc      540

aaggagaugg gcgaggucgc ccccgaguac cgccacgacu cccccgacug cggcaugauc      600

auccucugca ucgccgcccu cgucaucacc aagcucgccg ccggcgaccg cuccggccuc      660

accgccguca uccgccgcgc caacaacguc cucaagaacg agaugaagcg cuacaagggc      720

cuccucccca aggacaucgc caacuccuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgucu ucguccacuu cggcaucgcc caguccucca cccgcggcgg cucccgcguc      840

gagggcaucu ucgccggccu cuucaugaac gccuacggcg ccggccaggu caugcuccgc      900

uggggcgucc ucgccaaguc cgucaagaac aucaugcucg gccacgccuc cguccaggcc      960

gagauggagc aggucgucga ggucuacgag uacgcccaga agcucggcgg cgaggccggc     1020

uucuaccaca uccucaacaa ccccaaggcc ucccuccucu cccucaccca guucccccac     1080

uucuccuccg ucguccucgg caacgccgcc ggccucggca ucaugggcga guaccgcggc     1140

accccccgca accaggaccu cuacgacgcc gccaaggccu acgccgagca gcucaaggag     1200

aacggcguca ucaacuacuc cguccucgac cucaccgccg aggagcucga ggccaucaag     1260

caccagcuca accccaagga caacgacguc gagcucugag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10170
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10170
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuua auaaggauca gcuguugucc      180

ucuucaaaau acacaaucca aagaaguacu ggcgacagca uugauacgcc caacuaugac      240

guccagaagc acauaaauaa auuaugcggg augcugcuaa ucaccgagga ugcuaaccau      300

aaguucacag gacucauugg uaugcuguac gcaaugucca ggcuuggccg ggaagacacu      360

aucaagauuc ugcgcgaugc cggguaucac guuaaagcga auggagugga cguaaccaca      420

caucgacagg auaucaacgg caaggagaug aaauuugaag uguugacccu cgcuucucug      480

acuacagaga uacagaucaa uauugaaauc gagucgcgua agucauacaa aaagaugcug      540

aaggagaugg gugaagucgc cccugaguau agacacgaca gcccagauug ugggaugauu      600

auccucugca uagcagccuu agugauuacc aaacuggcug caggagacag gaguggccuu      660

acggccguua uccggcgcgc uaacaaugug uugaagaacg aaaugaaaag auacaagggc      720

cugcuaccga aagauauugc caauuccuuc uaugaggucu uugagaagca uccccacuuc      780

aucgacgugu uuguacacuu cgggaucgcg caaucuagca cuaggggagg uucccggguu      840

gaaggcauuu uugcaggacu cuucaugaac gccuacgggg cuggccaggu gaugcugcgc      900

uggggugucc uugccaaauc agugaagaau auaaugcugg ggcaugcaag ugugcaggcu      960

gagauggaac aggucguuga gguguacgaa uaugcccaaa aguugggagg cgaggcgggc     1020

uuuuaccaca uccucaacaa uccuaaagcc agccuguuau cucugaccca guucccacau     1080

uuuuccucag uagugcucgg gaacgcagcu ggacuuggua uuaugggcga guaucgaggg     1140

acacccagaa accaggaccu guacgaugcc gcuaaggccu augcagaaca guugaaagag     1200

aauggaguca ucaacuacag cgugcuagac cugacugccg aggaacucga agcuauaaag     1260

caccaacuga auccuaaaga uaacgacguu gagcuuugag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10171
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10171
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcugaac gacacccuga acaaggacca gcugcugagc      180

agcagcaagu acaccaucca gagaagcacc ggcgacagca ucgacacccc caacuacgac      240

gugcagaagc acaucaacaa gcugugcggc augcugcuga ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg caugcuguac gccaugagca gacugggcag agaggacacc      360

aucaagaucc ugagagacgc cggcuaccac gugaaggcca acggcgugga cgugaccacc      420

cacagacagg acaucaacgg caaggagaug aaguucgagg ugcugacccu ggccagccug      480

accaccgaga uccagaucaa caucgagauc gagagcagaa agagcuacaa gaagaugcug      540

aaggagaugg gcgagguggc ccccgaguac agacacgaca gccccgacug cggcaugauc      600

auccugugca ucgccgcccu ggugaucacc aagcuggccg ccggcgacag aagcggccug      660

accgccguga ucagaagagc caacaacgug cugaagaacg agaugaagag auacaagggc      720

cugcugccca aggacaucgc caacagcuuc uacgaggugu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc cagagcagca ccagaggcgg cagcagagug      840

gagggcaucu ucgccggccu guucaugaac gccuacggcg ccggccaggu gaugcugaga      900

uggggcgugc uggccaagag cgugaagaac aucaugcugg gccacgccag cgugcaggcc      960

gagauggagc agguggugga gguguacgag uacgcccaga agcugggcgg cgaggccggc     1020

uucuaccaca uccugaacaa ccccaaggcc agccugcuga gccugaccca guucccccac     1080

uucagcagcg uggugcuggg caacgccgcc ggccugggca ucaugggcga guacagaggc     1140

acccccagaa accaggaccu guacgacgcc gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacag cgugcuggac cugaccgccg aggagcugga ggccaucaag     1260

caccagcuga accccaagga caacgacgug gagcugugag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10172
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10172
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuga auaaggauca gcuucugucc      180

ucuagcaaau acacaaucca aagauccacg ggcgacucua uugauacccc caacuaugac      240

guccagaagc acaucaauaa acucugcggg augcugcuua uuacagagga ugcuaaccau      300

aaguucaccg gacugaucgg caugcucuac gccaugagcc ggcuggggcg cgaagacaca      360

auuaagaucc ugagagaugc gggauaucac guuaaagcua auggcgugga cgugaccaca      420

caucggcagg auaucaacgg gaaggagaug aaauuugaag uccucacccu ggccucccuu      480

acgaccgaga uucagaucaa uauugaaauc gagucucgca agagcuacaa aaagaugcug      540

aaggagaugg gagaaguggc cccugaguau agacacgacu ccccggauug uggcaugauu      600

auccucugca uugcugcccu gguuaucaca aaacuugcug ccggcgaccg gagcgggcug      660

accgcgguga uccgcagagc caacaauguc cucaagaacg aaaugaaacg guacaaggga      720

cugcugccca aagauauugc uaauucuuuc uaugaggugu uugagaagca uccucacuuc      780

aucgacguuu uugugcacuu cggcauugcc caauccagca cacgcggggg aucuagaguc      840

gaaggcaucu uugcuggacu cuucaugaac gccuacgggg cgggccaggu gaugcugcgg      900

uggggcgugc uugccaaauc cgucaagaau auuaugcugg ggcaugcuag cguucaggcc      960

gagauggaac agguggugga ggucuacgaa uaugcucaaa agcucggagg cgaggccggg     1020

uuuuaccaca uccugaacaa ucccaaagcc ucucuucugu cccucaccca guucccucau     1080

uuuagcuccg ugguucuggg aaacgcugcg ggccugggga ucaugggaga guaucgcggc     1140

acgcccagaa accaggaccu cuacgaugcc gcuaaggccu augccgaaca gcugaaagag     1200

aauggcguga uuaacuacuc uguccuugac cugacagcug aggaacucga agccaucaag     1260

caccaacuga auccuaaaga uaacgacgug gagcuuugag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10173
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10173
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac uaagcaaagu caaauuaaac gacacauuaa acaaagacca acucuuauca      180

ucaucaaaau acacaauaca aagaagcacc ggagacagua ucgacacacc aaacuaugac      240

guccaaaaac auauaaauaa auuaugcggc augcucuuaa ucacagaaga cgccaaccau      300

aaauuuacag gauuaauagg aauguuauau gcaaugucac gacuagguag agaagacaca      360

auaaaaauac uaagagacgc aggcuaucac guaaaagcaa auggaguaga cguaaccaca      420

cacagacaag acauaaaugg aaaagaaaug aaauuugaag uauuaacacu agcaucacua      480

acaacagaaa uacaaaucaa cauagaaaua gaaucaagaa aaagcuacaa aaaaauguua      540

aaagaaaugg gagaagucgc accagaauau agacaugauu caccagacug cggaaugaua      600

auacuaugca uagcagcccu aguaauuaca aaacuagcag caggagacag aagcggauua      660

acagcaguaa uaagaagagc aaacaacgua cuaaaaaacg aaaugaaaag auauaaagga      720

uuauuaccaa aagacauagc aaacucauuc uaugaaguau ucgaaaaaca cccccacuuu      780

auagacgucu ucguacacuu cggaauagcc caaucaucca caagaggagg aucaagaguc      840

gaaggaauau ucgcaggauu auucaugaac gcauauggcg caggacaagu aaugcuaaga      900

uggggaguac uagcaaaauc cgucaaaaac auaaugcuag gacacgcauc aguucaagca      960

gaaauggaac aaguaguaga aguauacgaa uacgcccaaa aacuaggagg agaagcagga     1020

uucuaccaca uacuaaauaa uccaaaagca ucacuacuaa gccuaaccca auuuccccac     1080

uucucaagug uaguauuagg aaaugcagcu ggacuaggaa uaaugggaga auacagagga     1140

acaccaagaa accaagacuu auacgacgca gcaaaagcau acgcagagca acuuaaagaa     1200

aacggaguaa uaaacuauag cguacuagac uuaacagcag aagaacugga agcaauaaaa     1260

caucaauuaa acccgaaaga caaugacgua gaauuauaag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10174
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10174
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac ucucgaaagu aaaacucaac gacacccuca acaaagacca acuccuuucc      180

agcuccaaau acaccaucca acgauccacc ggagacucca ucgacacgcc caacuacgac      240

guccagaaac acaucaacaa gcucugcgga augcuacuaa ucaccgagga cgccaaccac      300

aaauucacag gacuuauagg gaugcucuac gccauguccc gccucggacg cgaagacaca      360

auaaaaaucc uacgagacgc cggcuaccac guaaaggcaa acggcgucga cgucaccaca      420

cacagacaag acaucaacgg aaaggaaaug aaauucgaag uccucacccu cgccagccua      480

accaccgaga uccaaaucaa caucgaaauc gaaucacgca aauccuacaa gaaaaugcuc      540

aaagaaaugg gagaagucgc ccccgaauac cgucacgacu cgcccgacug cggcaugaua      600

auccuaugca ucgccgcacu cgucauaacc aaacucgccg ccggugaccg aucaggacug      660

acagcaguca uccgccgagc aaacaacgug cucaaaaacg aaaugaaacg cuacaaaggc      720

cuacucccca aagacaucgc caacuccuuc uacgaagucu ucgaaaaaca cccacacuuc      780

aucgacgucu ucguccacuu cggcaucgca caaucaucaa ccagaggcgg cagccgcguu      840

gaaggcaucu ucgcaggacu cuuuaugaac gccuacggcg ccggccaagu caugcuccgc      900

uggggcgucc uggcaaaaag cgucaaaaac aucaugcuag gccacgcuag cguccaagcc      960

gaaauggaac aagucgucga aguuuacgag uacgcacaaa aacucggcgg cgaagcaggc     1020

uucuaccaca uccuaaacaa ccccaaagcc ucccugcuau cacucaccca auucccccac     1080

uucuccagcg ucguccucgg caacgccgca ggacuaggca ucaugggaga auaccgcggg     1140

acaccgcgca accaagaccu cuacgacgcc gccaaagccu acgccgaaca acucaaagaa     1200

aacggcguca uaaacuacuc aguccucgac cucaccgccg aagaacucga agccaucaaa     1260

caccaacuca acccaaaaga caacgacguc gaauuauaag gacuaguccc uguucccaga     1320

gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  10175
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10175
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcucuuag caaagucaag uugaaugaua cacucaacaa agaucaacuu      120

cugucaucca gcaaauacac cauccaacgg agcacaggag auaguauuga uacuccuaau      180

uaugaugugc agaaacacau caauaaguua uguggcaugu uauuaaucac agaagaugcu      240

aaucauaaau ucacuggguu aauagguaug uuauaugcga ugucuagguu aggaagagaa      300

gacaccauaa aaauacucag agaugcggga uaucauguaa aagcaaaugg aguagaugua      360

acaacacauc gucaagacau uaauggaaaa gaaaugaaau uugaaguguu aacauuggca      420

agcuuaacaa cugaaauuca aaucaacauu gagauagaau cuagaaaauc cuacaaaaaa      480

augcuaaaag aaaugggaga gguagcucca gaauacaggc augacucucc ugauuguggg      540

augauaauau uauguauagc agcauuagua auaacuaaau uagcagcagg ggacagaucu      600

ggucuuacag ccgugauuag gagagcuaau aauguccuaa aaaaugaaau gaaacguuac      660

aaaggcuuac uacccaagga cauagccaac agcuucuaug aaguguuuga aaaacauccc      720

cacuuuauag auguuuuugu ucauuuuggu auagcacaau cuucuaccag agguggcagu      780

agaguugaag ggauuuuugc aggauuguuu augaaugccu auggugcagg gcaagugaug      840

uuacgguggg gagucuuagc aaaaucaguu aaaaauauua uguuaggaca ugcuagugug      900

caagcagaaa uggaacaagu uguugagguu uaugaauaug cccaaaaauu ggguggugaa      960

gcaggauucu accauauauu gaacaaccca aaagcaucau uauuaucuuu gacucaauuu     1020

ccucacuucu ccaguguagu auuaggcaau gcugcuggcc uaggcauaau gggagaguac     1080

agagguacac cgaggaauca agaucuauau gaugcagcaa aggcauaugc ugaacaacuc     1140

aaagaaaaug gugugauuaa cuacagugua cuagacuuga cagcagaaga acuagaggcu     1200

aucaaacauc agcuuaaucc aaaagauaau gauguagagc uuugaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10176
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10176
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cucaacgaca cccugaacaa ggaccagcug      120

cucuccagcu ccaaguacac cauccagcgc agcaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcug ugcgggaugc ugcucaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucgggaug cuguacgcga ugagccggcu cggccgcgag      300

gacacgauca agauccugcg ggacgccggg uaccacguga aggccaacgg cguggacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgaggugcu gacccucgcc      420

ucccugacga ccgagaucca gaucaacauc gagaucgaga gccggaaguc cuacaagaag      480

augcugaagg agauggggga gguggccccg gaguaccgcc acgacagccc cgacugcggc      540

augaucaucc ucugcaucgc ggcccugguc aucaccaagc uggccgccgg ggaccggucc      600

ggccucaccg cggugauccg ccgggccaac aacgugcuga agaacgagau gaagcgcuac      660

aaggggcugc uccccaagga caucgccaac agcuucuacg aggucuucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccagu ccagcacgcg gggcgggucc      780

cgcgucgagg gcaucuucgc cgggcuguuc augaacgcgu acggcgccgg ccaggugaug      840

cugcgguggg gcgugcucgc caagagcguc aagaacauca ugcuggggca cgccuccgug      900

caggccgaga uggagcaggu cguggaggug uacgaguacg cgcagaagcu cgggggcgag      960

gccggguucu accacauccu gaacaacccg aaggccagcc ugcugucccu cacccaguuc     1020

ccccacuuca gcagcguggu ccugggcaac gccgccggcc uggggaucau gggcgaguac     1080

cgcgggacgc cccggaacca ggaccucuac gacgcggcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacuccgug cuggaccuca ccgccgagga gcuggaggcg     1200

aucaagcacc agcugaaccc caaggacaac gacgucgagc ucugaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10177
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10177
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccucuc caaggucaag cucaacgaca cccucaacaa ggaccagcuc      120

cucuccuccu ccaaguacac cauccagcgc uccaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcuc ugcggcaugc uccucaucac cgaggacgcc      240

aaccacaagu ucaccggccu caucggcaug cucuacgcca ugucccgccu cggccgcgag      300

gacaccauca agauccuccg cgacgccggc uaccacguca aggccaacgg cgucgacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgagguccu cacccucgcc      420

ucccucacca ccgagaucca gaucaacauc gagaucgagu cccgcaaguc cuacaagaag      480

augcucaagg agaugggcga ggucgccccc gaguaccgcc acgacucccc cgacugcggc      540

augaucaucc ucugcaucgc cgcccucguc aucaccaagc ucgccgccgg cgaccgcucc      600

ggccucaccg ccgucauccg ccgcgccaac aacguccuca agaacgagau gaagcgcuac      660

aagggccucc uccccaagga caucgccaac uccuucuacg aggucuucga gaagcacccc      720

cacuucaucg acgucuucgu ccacuucggc aucgcccagu ccuccacccg cggcggcucc      780

cgcgucgagg gcaucuucgc cggccucuuc augaacgccu acggcgccgg ccaggucaug      840

cuccgcuggg gcguccucgc caaguccguc aagaacauca ugcucggcca cgccuccguc      900

caggccgaga uggagcaggu cgucgagguc uacgaguacg cccagaagcu cggcggcgag      960

gccggcuucu accacauccu caacaacccc aaggccuccc uccucucccu cacccaguuc     1020

ccccacuucu ccuccgucgu ccucggcaac gccgccggcc ucggcaucau gggcgaguac     1080

cgcggcaccc cccgcaacca ggaccucuac gacgccgcca aggccuacgc cgagcagcuc     1140

aaggagaacg gcgucaucaa cuacuccguc cucgaccuca ccgccgagga gcucgaggcc     1200

aucaagcacc agcucaaccc caaggacaac gacgucgagc ucugaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10178
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10178
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccuuaauaa ggaucagcug      120

uuguccucuu caaaauacac aauccaaaga aguacuggcg acagcauuga uacgcccaac      180

uaugacgucc agaagcacau aaauaaauua ugcgggaugc ugcuaaucac cgaggaugcu      240

aaccauaagu ucacaggacu cauugguaug cuguacgcaa uguccaggcu uggccgggaa      300

gacacuauca agauucugcg cgaugccggg uaucacguua aagcgaaugg aguggacgua      360

accacacauc gacaggauau caacggcaag gagaugaaau uugaaguguu gacccucgcu      420

ucucugacua cagagauaca gaucaauauu gaaaucgagu cgcguaaguc auacaaaaag      480

augcugaagg agauggguga agucgccccu gaguauagac acgacagccc agauuguggg      540

augauuaucc ucugcauagc agccuuagug auuaccaaac uggcugcagg agacaggagu      600

ggccuuacgg ccguuauccg gcgcgcuaac aauguguuga agaacgaaau gaaaagauac      660

aagggccugc uaccgaaaga uauugccaau uccuucuaug aggucuuuga gaagcauccc      720

cacuucaucg acguguuugu acacuucggg aucgcgcaau cuagcacuag gggagguucc      780

cggguugaag gcauuuuugc aggacucuuc augaacgccu acggggcugg ccaggugaug      840

cugcgcuggg guguccuugc caaaucagug aagaauauaa ugcuggggca ugcaagugug      900

caggcugaga uggaacaggu cguugaggug uacgaauaug cccaaaaguu gggaggcgag      960

gcgggcuuuu accacauccu caacaauccu aaagccagcc uguuaucucu gacccaguuc     1020

ccacauuuuu ccucaguagu gcucgggaac gcagcuggac uugguauuau gggcgaguau     1080

cgagggacac ccagaaacca ggaccuguac gaugccgcua aggccuaugc agaacaguug     1140

aaagagaaug gagucaucaa cuacagcgug cuagaccuga cugccgagga acucgaagcu     1200

auaaagcacc aacugaaucc uaaagauaac gacguugagc uuugaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10179
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10179
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cugaacgaca cccugaacaa ggaccagcug      120

cugagcagca gcaaguacac cauccagaga agcaccggcg acagcaucga cacccccaac      180

uacgacgugc agaagcacau caacaagcug ugcggcaugc ugcugaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucggcaug cuguacgcca ugagcagacu gggcagagag      300

gacaccauca agauccugag agacgccggc uaccacguga aggccaacgg cguggacgug      360

accacccaca gacaggacau caacggcaag gagaugaagu ucgaggugcu gacccuggcc      420

agccugacca ccgagaucca gaucaacauc gagaucgaga gcagaaagag cuacaagaag      480

augcugaagg agaugggcga gguggccccc gaguacagac acgacagccc cgacugcggc      540

augaucaucc ugugcaucgc cgcccuggug aucaccaagc uggccgccgg cgacagaagc      600

ggccugaccg ccgugaucag aagagccaac aacgugcuga agaacgagau gaagagauac      660

aagggccugc ugcccaagga caucgccaac agcuucuacg agguguucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccaga gcagcaccag aggcggcagc      780

agaguggagg gcaucuucgc cggccuguuc augaacgccu acggcgccgg ccaggugaug      840

cugagauggg gcgugcuggc caagagcgug aagaacauca ugcugggcca cgccagcgug      900

caggccgaga uggagcaggu gguggaggug uacgaguacg cccagaagcu gggcggcgag      960

gccggcuucu accacauccu gaacaacccc aaggccagcc ugcugagccu gacccaguuc     1020

ccccacuuca gcagcguggu gcugggcaac gccgccggcc ugggcaucau gggcgaguac     1080

agaggcaccc ccagaaacca ggaccuguac gacgccgcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacagcgug cuggaccuga ccgccgagga gcuggaggcc     1200

aucaagcacc agcugaaccc caaggacaac gacguggagc ugugaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10180
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10180
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccugaauaa ggaucagcuu      120

cuguccucua gcaaauacac aauccaaaga uccacgggcg acucuauuga uacccccaac      180

uaugacgucc agaagcacau caauaaacuc ugcgggaugc ugcuuauuac agaggaugcu      240

aaccauaagu ucaccggacu gaucggcaug cucuacgcca ugagccggcu ggggcgcgaa      300

gacacaauua agauccugag agaugcggga uaucacguua aagcuaaugg cguggacgug      360

accacacauc ggcaggauau caacgggaag gagaugaaau uugaaguccu cacccuggcc      420

ucccuuacga ccgagauuca gaucaauauu gaaaucgagu cucgcaagag cuacaaaaag      480

augcugaagg agaugggaga aguggccccu gaguauagac acgacucccc ggauuguggc      540

augauuaucc ucugcauugc ugcccugguu aucacaaaac uugcugccgg cgaccggagc      600

gggcugaccg cggugauccg cagagccaac aauguccuca agaacgaaau gaaacgguac      660

aagggacugc ugcccaaaga uauugcuaau ucuuucuaug agguguuuga gaagcauccu      720

cacuucaucg acguuuuugu gcacuucggc auugcccaau ccagcacacg cgggggaucu      780

agagucgaag gcaucuuugc uggacucuuc augaacgccu acggggcggg ccaggugaug      840

cugcgguggg gcgugcuugc caaauccguc aagaauauua ugcuggggca ugcuagcguu      900

caggccgaga uggaacaggu gguggagguc uacgaauaug cucaaaagcu cggaggcgag      960

gccggguuuu accacauccu gaacaauccc aaagccucuc uucugucccu cacccaguuc     1020

ccucauuuua gcuccguggu ucugggaaac gcugcgggcc uggggaucau gggagaguau     1080

cgcggcacgc ccagaaacca ggaccucuac gaugccgcua aggccuaugc cgaacagcug     1140

aaagagaaug gcgugauuaa cuacucuguc cuugaccuga cagcugagga acucgaagcc     1200

aucaagcacc aacugaaucc uaaagauaac gacguggagc uuugaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10181
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10181
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacuaag caaagucaaa uuaaacgaca cauuaaacaa agaccaacuc      120

uuaucaucau caaaauacac aauacaaaga agcaccggag acaguaucga cacaccaaac      180

uaugacgucc aaaaacauau aaauaaauua ugcggcaugc ucuuaaucac agaagacgcc      240

aaccauaaau uuacaggauu aauaggaaug uuauaugcaa ugucacgacu agguagagaa      300

gacacaauaa aaauacuaag agacgcaggc uaucacguaa aagcaaaugg aguagacgua      360

accacacaca gacaagacau aaauggaaaa gaaaugaaau uugaaguauu aacacuagca      420

ucacuaacaa cagaaauaca aaucaacaua gaaauagaau caagaaaaag cuacaaaaaa      480

auguuaaaag aaaugggaga agucgcacca gaauauagac augauucacc agacugcgga      540

augauaauac uaugcauagc agcccuagua auuacaaaac uagcagcagg agacagaagc      600

ggauuaacag caguaauaag aagagcaaac aacguacuaa aaaacgaaau gaaaagauau      660

aaaggauuau uaccaaaaga cauagcaaac ucauucuaug aaguauucga aaaacacccc      720

cacuuuauag acgucuucgu acacuucgga auagcccaau cauccacaag aggaggauca      780

agagucgaag gaauauucgc aggauuauuc augaacgcau auggcgcagg acaaguaaug      840

cuaagauggg gaguacuagc aaaauccguc aaaaacauaa ugcuaggaca cgcaucaguu      900

caagcagaaa uggaacaagu aguagaagua uacgaauacg cccaaaaacu aggaggagaa      960

gcaggauucu accacauacu aaauaaucca aaagcaucac uacuaagccu aacccaauuu     1020

ccccacuucu caaguguagu auuaggaaau gcagcuggac uaggaauaau gggagaauac     1080

agaggaacac caagaaacca agacuuauac gacgcagcaa aagcauacgc agagcaacuu     1140

aaagaaaacg gaguaauaaa cuauagcgua cuagacuuaa cagcagaaga acuggaagca     1200

auaaaacauc aauuaaaccc gaaagacaau gacguagaau uauaaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10182
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10182
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacucuc gaaaguaaaa cucaacgaca cccucaacaa agaccaacuc      120

cuuuccagcu ccaaauacac cauccaacga uccaccggag acuccaucga cacgcccaac      180

uacgacgucc agaaacacau caacaagcuc ugcggaaugc uacuaaucac cgaggacgcc      240

aaccacaaau ucacaggacu uauagggaug cucuacgcca ugucccgccu cggacgcgaa      300

gacacaauaa aaauccuacg agacgccggc uaccacguaa aggcaaacgg cgucgacguc      360

accacacaca gacaagacau caacggaaag gaaaugaaau ucgaaguccu cacccucgcc      420

agccuaacca ccgagaucca aaucaacauc gaaaucgaau cacgcaaauc cuacaagaaa      480

augcucaaag aaaugggaga agucgccccc gaauaccguc acgacucgcc cgacugcggc      540

augauaaucc uaugcaucgc cgcacucguc auaaccaaac ucgccgccgg ugaccgauca      600

ggacugacag cagucauccg ccgagcaaac aacgugcuca aaaacgaaau gaaacgcuac      660

aaaggccuac uccccaaaga caucgccaac uccuucuacg aagucuucga aaaacaccca      720

cacuucaucg acgucuucgu ccacuucggc aucgcacaau caucaaccag aggcggcagc      780

cgcguugaag gcaucuucgc aggacucuuu augaacgccu acggcgccgg ccaagucaug      840

cuccgcuggg gcguccuggc aaaaagcguc aaaaacauca ugcuaggcca cgcuagcguc      900

caagccgaaa uggaacaagu cgucgaaguu uacgaguacg cacaaaaacu cggcggcgaa      960

gcaggcuucu accacauccu aaacaacccc aaagccuccc ugcuaucacu cacccaauuc     1020

ccccacuucu ccagcgucgu ccucggcaac gccgcaggac uaggcaucau gggagaauac     1080

cgcgggacac cgcgcaacca agaccucuac gacgccgcca aagccuacgc cgaacaacuc     1140

aaagaaaacg gcgucauaaa cuacucaguc cucgaccuca ccgccgaaga acucgaagcc     1200

aucaaacacc aacucaaccc aaaagacaac gacgucgaau uauaaggacu agucccuguu     1260

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  10183
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10183
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcucuuagca aagucaaguu gaaugauaca cucaacaaag aucaacuucu gucauccagc      300

aaauacacca uccaacggag cacaggagau aguauugaua cuccuaauua ugaugugcag      360

aaacacauca auaaguuaug uggcauguua uuaaucacag aagaugcuaa ucauaaauuc      420

acuggguuaa uagguauguu auaugcgaug ucuagguuag gaagagaaga caccauaaaa      480

auacucagag augcgggaua ucauguaaaa gcaaauggag uagauguaac aacacaucgu      540

caagacauua auggaaaaga aaugaaauuu gaaguguuaa cauuggcaag cuuaacaacu      600

gaaauucaaa ucaacauuga gauagaaucu agaaaauccu acaaaaaaau gcuaaaagaa      660

augggagagg uagcuccaga auacaggcau gacucuccug auugugggau gauaauauua      720

uguauagcag cauuaguaau aacuaaauua gcagcagggg acagaucugg ucuuacagcc      780

gugauuagga gagcuaauaa uguccuaaaa aaugaaauga aacguuacaa aggcuuacua      840

cccaaggaca uagccaacag cuucuaugaa guguuugaaa aacaucccca cuuuauagau      900

guuuuuguuc auuuugguau agcacaaucu ucuaccagag guggcaguag aguugaaggg      960

auuuuugcag gauuguuuau gaaugccuau ggugcagggc aagugauguu acggugggga     1020

gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug cuagugugca agcagaaaug     1080

gaacaaguug uugagguuua ugaauaugcc caaaaauugg guggugaagc aggauucuac     1140

cauauauuga acaacccaaa agcaucauua uuaucuuuga cucaauuucc ucacuucucc     1200

aguguaguau uaggcaaugc ugcuggccua ggcauaaugg gagaguacag agguacaccg     1260

aggaaucaag aucuauauga ugcagcaaag gcauaugcug aacaacucaa agaaaauggu     1320

gugauuaacu acaguguacu agacuugaca gcagaagaac uagaggcuau caaacaucag     1380

cuuaauccaa aagauaauga uguagagcuu ugaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10184
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10184
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcccugagca aggugaagcu caacgacacc cugaacaagg accagcugcu cuccagcucc      300

aaguacacca uccagcgcag caccggcgac uccaucgaca cccccaacua cgacguccag      360

aagcacauca acaagcugug cgggaugcug cucaucaccg aggacgccaa ccacaaguuc      420

accggccuga ucgggaugcu guacgcgaug agccggcucg gccgcgagga cacgaucaag      480

auccugcggg acgccgggua ccacgugaag gccaacggcg uggacgucac cacccaccgc      540

caggacauca acggcaagga gaugaaguuc gaggugcuga cccucgccuc ccugacgacc      600

gagauccaga ucaacaucga gaucgagagc cggaaguccu acaagaagau gcugaaggag      660

augggggagg uggccccgga guaccgccac gacagccccg acugcggcau gaucauccuc      720

ugcaucgcgg cccuggucau caccaagcug gccgccgggg accgguccgg ccucaccgcg      780

gugauccgcc gggccaacaa cgugcugaag aacgagauga agcgcuacaa ggggcugcuc      840

cccaaggaca ucgccaacag cuucuacgag gucuucgaga agcaccccca cuucaucgac      900

guguucgugc acuucggcau cgcccagucc agcacgcggg gcgggucccg cgucgagggc      960

aucuucgccg ggcuguucau gaacgcguac ggcgccggcc aggugaugcu gcgguggggc     1020

gugcucgcca agagcgucaa gaacaucaug cuggggcacg ccuccgugca ggccgagaug     1080

gagcaggucg uggaggugua cgaguacgcg cagaagcucg ggggcgaggc cggguucuac     1140

cacauccuga acaacccgaa ggccagccug cugucccuca cccaguuccc ccacuucagc     1200

agcguggucc ugggcaacgc cgccggccug gggaucaugg gcgaguaccg cgggacgccc     1260

cggaaccagg accucuacga cgcggccaag gccuacgccg agcagcugaa ggagaacggc     1320

gugaucaacu acuccgugcu ggaccucacc gccgaggagc uggaggcgau caagcaccag     1380

cugaacccca aggacaacga cgucgagcuc ugaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10185
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10185
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcccucucca aggucaagcu caacgacacc cucaacaagg accagcuccu cuccuccucc      300

aaguacacca uccagcgcuc caccggcgac uccaucgaca cccccaacua cgacguccag      360

aagcacauca acaagcucug cggcaugcuc cucaucaccg aggacgccaa ccacaaguuc      420

accggccuca ucggcaugcu cuacgccaug ucccgccucg gccgcgagga caccaucaag      480

auccuccgcg acgccggcua ccacgucaag gccaacggcg ucgacgucac cacccaccgc      540

caggacauca acggcaagga gaugaaguuc gagguccuca cccucgccuc ccucaccacc      600

gagauccaga ucaacaucga gaucgagucc cgcaaguccu acaagaagau gcucaaggag      660

augggcgagg ucgcccccga guaccgccac gacucccccg acugcggcau gaucauccuc      720

ugcaucgccg cccucgucau caccaagcuc gccgccggcg accgcuccgg ccucaccgcc      780

gucauccgcc gcgccaacaa cguccucaag aacgagauga agcgcuacaa gggccuccuc      840

cccaaggaca ucgccaacuc cuucuacgag gucuucgaga agcaccccca cuucaucgac      900

gucuucgucc acuucggcau cgcccagucc uccacccgcg gcggcucccg cgucgagggc      960

aucuucgccg gccucuucau gaacgccuac ggcgccggcc aggucaugcu ccgcuggggc     1020

guccucgcca aguccgucaa gaacaucaug cucggccacg ccuccgucca ggccgagaug     1080

gagcaggucg ucgaggucua cgaguacgcc cagaagcucg gcggcgaggc cggcuucuac     1140

cacauccuca acaaccccaa ggccucccuc cucucccuca cccaguuccc ccacuucucc     1200

uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg gcgaguaccg cggcaccccc     1260

cgcaaccagg accucuacga cgccgccaag gccuacgccg agcagcucaa ggagaacggc     1320

gucaucaacu acuccguccu cgaccucacc gccgaggagc ucgaggccau caagcaccag     1380

cucaacccca aggacaacga cgucgagcuc ugaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10186
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10186
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcccugagca aggugaaacu caacgacacc cuuaauaagg aucagcuguu guccucuuca      300

aaauacacaa uccaaagaag uacuggcgac agcauugaua cgcccaacua ugacguccag      360

aagcacauaa auaaauuaug cgggaugcug cuaaucaccg aggaugcuaa ccauaaguuc      420

acaggacuca uugguaugcu guacgcaaug uccaggcuug gccgggaaga cacuaucaag      480

auucugcgcg augccgggua ucacguuaaa gcgaauggag uggacguaac cacacaucga      540

caggauauca acggcaagga gaugaaauuu gaaguguuga cccucgcuuc ucugacuaca      600

gagauacaga ucaauauuga aaucgagucg cguaagucau acaaaaagau gcugaaggag      660

augggugaag ucgccccuga guauagacac gacagcccag auugugggau gauuauccuc      720

ugcauagcag ccuuagugau uaccaaacug gcugcaggag acaggagugg ccuuacggcc      780

guuauccggc gcgcuaacaa uguguugaag aacgaaauga aaagauacaa gggccugcua      840

ccgaaagaua uugccaauuc cuucuaugag gucuuugaga agcaucccca cuucaucgac      900

guguuuguac acuucgggau cgcgcaaucu agcacuaggg gagguucccg gguugaaggc      960

auuuuugcag gacucuucau gaacgccuac ggggcuggcc aggugaugcu gcgcuggggu     1020

guccuugcca aaucagugaa gaauauaaug cuggggcaug caagugugca ggcugagaug     1080

gaacaggucg uugaggugua cgaauaugcc caaaaguugg gaggcgaggc gggcuuuuac     1140

cacauccuca acaauccuaa agccagccug uuaucucuga cccaguuccc acauuuuucc     1200

ucaguagugc ucgggaacgc agcuggacuu gguauuaugg gcgaguaucg agggacaccc     1260

agaaaccagg accuguacga ugccgcuaag gccuaugcag aacaguugaa agagaaugga     1320

gucaucaacu acagcgugcu agaccugacu gccgaggaac ucgaagcuau aaagcaccaa     1380

cugaauccua aagauaacga cguugagcuu ugaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10187
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10187
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcccugagca aggugaagcu gaacgacacc cugaacaagg accagcugcu gagcagcagc      300

aaguacacca uccagagaag caccggcgac agcaucgaca cccccaacua cgacgugcag      360

aagcacauca acaagcugug cggcaugcug cugaucaccg aggacgccaa ccacaaguuc      420

accggccuga ucggcaugcu guacgccaug agcagacugg gcagagagga caccaucaag      480

auccugagag acgccggcua ccacgugaag gccaacggcg uggacgugac cacccacaga      540

caggacauca acggcaagga gaugaaguuc gaggugcuga cccuggccag ccugaccacc      600

gagauccaga ucaacaucga gaucgagagc agaaagagcu acaagaagau gcugaaggag      660

augggcgagg uggcccccga guacagacac gacagccccg acugcggcau gaucauccug      720

ugcaucgccg cccuggugau caccaagcug gccgccggcg acagaagcgg ccugaccgcc      780

gugaucagaa gagccaacaa cgugcugaag aacgagauga agagauacaa gggccugcug      840

cccaaggaca ucgccaacag cuucuacgag guguucgaga agcaccccca cuucaucgac      900

guguucgugc acuucggcau cgcccagagc agcaccagag gcggcagcag aguggagggc      960

aucuucgccg gccuguucau gaacgccuac ggcgccggcc aggugaugcu gagauggggc     1020

gugcuggcca agagcgugaa gaacaucaug cugggccacg ccagcgugca ggccgagaug     1080

gagcaggugg uggaggugua cgaguacgcc cagaagcugg gcggcgaggc cggcuucuac     1140

cacauccuga acaaccccaa ggccagccug cugagccuga cccaguuccc ccacuucagc     1200

agcguggugc ugggcaacgc cgccggccug ggcaucaugg gcgaguacag aggcaccccc     1260

agaaaccagg accuguacga cgccgccaag gccuacgccg agcagcugaa ggagaacggc     1320

gugaucaacu acagcgugcu ggaccugacc gccgaggagc uggaggccau caagcaccag     1380

cugaacccca aggacaacga cguggagcug ugaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10188
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10188
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcccugagca aggugaaacu caacgacacc cugaauaagg aucagcuucu guccucuagc      300

aaauacacaa uccaaagauc cacgggcgac ucuauugaua cccccaacua ugacguccag      360

aagcacauca auaaacucug cgggaugcug cuuauuacag aggaugcuaa ccauaaguuc      420

accggacuga ucggcaugcu cuacgccaug agccggcugg ggcgcgaaga cacaauuaag      480

auccugagag augcgggaua ucacguuaaa gcuaauggcg uggacgugac cacacaucgg      540

caggauauca acgggaagga gaugaaauuu gaaguccuca cccuggccuc ccuuacgacc      600

gagauucaga ucaauauuga aaucgagucu cgcaagagcu acaaaaagau gcugaaggag      660

augggagaag uggccccuga guauagacac gacuccccgg auuguggcau gauuauccuc      720

ugcauugcug cccugguuau cacaaaacuu gcugccggcg accggagcgg gcugaccgcg      780

gugauccgca gagccaacaa uguccucaag aacgaaauga aacgguacaa gggacugcug      840

cccaaagaua uugcuaauuc uuucuaugag guguuugaga agcauccuca cuucaucgac      900

guuuuugugc acuucggcau ugcccaaucc agcacacgcg ggggaucuag agucgaaggc      960

aucuuugcug gacucuucau gaacgccuac ggggcgggcc aggugaugcu gcgguggggc     1020

gugcuugcca aauccgucaa gaauauuaug cuggggcaug cuagcguuca ggccgagaug     1080

gaacaggugg uggaggucua cgaauaugcu caaaagcucg gaggcgaggc cggguuuuac     1140

cacauccuga acaaucccaa agccucucuu cugucccuca cccaguuccc ucauuuuagc     1200

uccgugguuc ugggaaacgc ugcgggccug gggaucaugg gagaguaucg cggcacgccc     1260

agaaaccagg accucuacga ugccgcuaag gccuaugccg aacagcugaa agagaauggc     1320

gugauuaacu acucuguccu ugaccugaca gcugaggaac ucgaagccau caagcaccaa     1380

cugaauccua aagauaacga cguggagcuu ugaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10189
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10189
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcacuaagca aagucaaauu aaacgacaca uuaaacaaag accaacucuu aucaucauca      300

aaauacacaa uacaaagaag caccggagac aguaucgaca caccaaacua ugacguccaa      360

aaacauauaa auaaauuaug cggcaugcuc uuaaucacag aagacgccaa ccauaaauuu      420

acaggauuaa uaggaauguu auaugcaaug ucacgacuag guagagaaga cacaauaaaa      480

auacuaagag acgcaggcua ucacguaaaa gcaaauggag uagacguaac cacacacaga      540

caagacauaa auggaaaaga aaugaaauuu gaaguauuaa cacuagcauc acuaacaaca      600

gaaauacaaa ucaacauaga aauagaauca agaaaaagcu acaaaaaaau guuaaaagaa      660

augggagaag ucgcaccaga auauagacau gauucaccag acugcggaau gauaauacua      720

ugcauagcag cccuaguaau uacaaaacua gcagcaggag acagaagcgg auuaacagca      780

guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga aaagauauaa aggauuauua      840

ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa aacaccccca cuuuauagac      900

gucuucguac acuucggaau agcccaauca uccacaagag gaggaucaag agucgaagga      960

auauucgcag gauuauucau gaacgcauau ggcgcaggac aaguaaugcu aagaugggga     1020

guacuagcaa aauccgucaa aaacauaaug cuaggacacg caucaguuca agcagaaaug     1080

gaacaaguag uagaaguaua cgaauacgcc caaaaacuag gaggagaagc aggauucuac     1140

cacauacuaa auaauccaaa agcaucacua cuaagccuaa cccaauuucc ccacuucuca     1200

aguguaguau uaggaaaugc agcuggacua ggaauaaugg gagaauacag aggaacacca     1260

agaaaccaag acuuauacga cgcagcaaaa gcauacgcag agcaacuuaa agaaaacgga     1320

guaauaaacu auagcguacu agacuuaaca gcagaagaac uggaagcaau aaaacaucaa     1380

uuaaacccga aagacaauga cguagaauua uaaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10190
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10190
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gcacucucga aaguaaaacu caacgacacc cucaacaaag accaacuccu uuccagcucc      300

aaauacacca uccaacgauc caccggagac uccaucgaca cgcccaacua cgacguccag      360

aaacacauca acaagcucug cggaaugcua cuaaucaccg aggacgccaa ccacaaauuc      420

acaggacuua uagggaugcu cuacgccaug ucccgccucg gacgcgaaga cacaauaaaa      480

auccuacgag acgccggcua ccacguaaag gcaaacggcg ucgacgucac cacacacaga      540

caagacauca acggaaagga aaugaaauuc gaaguccuca cccucgccag ccuaaccacc      600

gagauccaaa ucaacaucga aaucgaauca cgcaaauccu acaagaaaau gcucaaagaa      660

augggagaag ucgcccccga auaccgucac gacucgcccg acugcggcau gauaauccua      720

ugcaucgccg cacucgucau aaccaaacuc gccgccggug accgaucagg acugacagca      780

gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga aacgcuacaa aggccuacuc      840

cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa aacacccaca cuucaucgac      900

gucuucgucc acuucggcau cgcacaauca ucaaccagag gcggcagccg cguugaaggc      960

aucuucgcag gacucuuuau gaacgccuac ggcgccggcc aagucaugcu ccgcuggggc     1020

guccuggcaa aaagcgucaa aaacaucaug cuaggccacg cuagcgucca agccgaaaug     1080

gaacaagucg ucgaaguuua cgaguacgca caaaaacucg gcggcgaagc aggcuucuac     1140

cacauccuaa acaaccccaa agccucccug cuaucacuca cccaauuccc ccacuucucc     1200

agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg gagaauaccg cgggacaccg     1260

cgcaaccaag accucuacga cgccgccaaa gccuacgccg aacaacucaa agaaaacggc     1320

gucauaaacu acucaguccu cgaccucacc gccgaagaac ucgaagccau caaacaccaa     1380

cucaacccaa aagacaacga cgucgaauua uaaggacuag uguccaccug ucccuccugg     1440

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10191
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10191
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcucuuagca aagucaaguu gaaugauaca cucaacaaag aucaacuucu gucauccagc      120

aaauacacca uccaacggag cacaggagau aguauugaua cuccuaauua ugaugugcag      180

aaacacauca auaaguuaug uggcauguua uuaaucacag aagaugcuaa ucauaaauuc      240

acuggguuaa uagguauguu auaugcgaug ucuagguuag gaagagaaga caccauaaaa      300

auacucagag augcgggaua ucauguaaaa gcaaauggag uagauguaac aacacaucgu      360

caagacauua auggaaaaga aaugaaauuu gaaguguuaa cauuggcaag cuuaacaacu      420

gaaauucaaa ucaacauuga gauagaaucu agaaaauccu acaaaaaaau gcuaaaagaa      480

augggagagg uagcuccaga auacaggcau gacucuccug auugugggau gauaauauua      540

uguauagcag cauuaguaau aacuaaauua gcagcagggg acagaucugg ucuuacagcc      600

gugauuagga gagcuaauaa uguccuaaaa aaugaaauga aacguuacaa aggcuuacua      660

cccaaggaca uagccaacag cuucuaugaa guguuugaaa aacaucccca cuuuauagau      720

guuuuuguuc auuuugguau agcacaaucu ucuaccagag guggcaguag aguugaaggg      780

auuuuugcag gauuguuuau gaaugccuau ggugcagggc aagugauguu acggugggga      840

gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug cuagugugca agcagaaaug      900

gaacaaguug uugagguuua ugaauaugcc caaaaauugg guggugaagc aggauucuac      960

cauauauuga acaacccaaa agcaucauua uuaucuuuga cucaauuucc ucacuucucc     1020

aguguaguau uaggcaaugc ugcuggccua ggcauaaugg gagaguacag agguacaccg     1080

aggaaucaag aucuauauga ugcagcaaag gcauaugcug aacaacucaa agaaaauggu     1140

gugauuaacu acaguguacu agacuugaca gcagaagaac uagaggcuau caaacaucag     1200

cuuaauccaa aagauaauga uguagagcuu ugaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10192
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10192
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcccugagca aggugaagcu caacgacacc cugaacaagg accagcugcu cuccagcucc      120

aaguacacca uccagcgcag caccggcgac uccaucgaca cccccaacua cgacguccag      180

aagcacauca acaagcugug cgggaugcug cucaucaccg aggacgccaa ccacaaguuc      240

accggccuga ucgggaugcu guacgcgaug agccggcucg gccgcgagga cacgaucaag      300

auccugcggg acgccgggua ccacgugaag gccaacggcg uggacgucac cacccaccgc      360

caggacauca acggcaagga gaugaaguuc gaggugcuga cccucgccuc ccugacgacc      420

gagauccaga ucaacaucga gaucgagagc cggaaguccu acaagaagau gcugaaggag      480

augggggagg uggccccgga guaccgccac gacagccccg acugcggcau gaucauccuc      540

ugcaucgcgg cccuggucau caccaagcug gccgccgggg accgguccgg ccucaccgcg      600

gugauccgcc gggccaacaa cgugcugaag aacgagauga agcgcuacaa ggggcugcuc      660

cccaaggaca ucgccaacag cuucuacgag gucuucgaga agcaccccca cuucaucgac      720

guguucgugc acuucggcau cgcccagucc agcacgcggg gcgggucccg cgucgagggc      780

aucuucgccg ggcuguucau gaacgcguac ggcgccggcc aggugaugcu gcgguggggc      840

gugcucgcca agagcgucaa gaacaucaug cuggggcacg ccuccgugca ggccgagaug      900

gagcaggucg uggaggugua cgaguacgcg cagaagcucg ggggcgaggc cggguucuac      960

cacauccuga acaacccgaa ggccagccug cugucccuca cccaguuccc ccacuucagc     1020

agcguggucc ugggcaacgc cgccggccug gggaucaugg gcgaguaccg cgggacgccc     1080

cggaaccagg accucuacga cgcggccaag gccuacgccg agcagcugaa ggagaacggc     1140

gugaucaacu acuccgugcu ggaccucacc gccgaggagc uggaggcgau caagcaccag     1200

cugaacccca aggacaacga cgucgagcuc ugaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10193
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10193
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcccucucca aggucaagcu caacgacacc cucaacaagg accagcuccu cuccuccucc      120

aaguacacca uccagcgcuc caccggcgac uccaucgaca cccccaacua cgacguccag      180

aagcacauca acaagcucug cggcaugcuc cucaucaccg aggacgccaa ccacaaguuc      240

accggccuca ucggcaugcu cuacgccaug ucccgccucg gccgcgagga caccaucaag      300

auccuccgcg acgccggcua ccacgucaag gccaacggcg ucgacgucac cacccaccgc      360

caggacauca acggcaagga gaugaaguuc gagguccuca cccucgccuc ccucaccacc      420

gagauccaga ucaacaucga gaucgagucc cgcaaguccu acaagaagau gcucaaggag      480

augggcgagg ucgcccccga guaccgccac gacucccccg acugcggcau gaucauccuc      540

ugcaucgccg cccucgucau caccaagcuc gccgccggcg accgcuccgg ccucaccgcc      600

gucauccgcc gcgccaacaa cguccucaag aacgagauga agcgcuacaa gggccuccuc      660

cccaaggaca ucgccaacuc cuucuacgag gucuucgaga agcaccccca cuucaucgac      720

gucuucgucc acuucggcau cgcccagucc uccacccgcg gcggcucccg cgucgagggc      780

aucuucgccg gccucuucau gaacgccuac ggcgccggcc aggucaugcu ccgcuggggc      840

guccucgcca aguccgucaa gaacaucaug cucggccacg ccuccgucca ggccgagaug      900

gagcaggucg ucgaggucua cgaguacgcc cagaagcucg gcggcgaggc cggcuucuac      960

cacauccuca acaaccccaa ggccucccuc cucucccuca cccaguuccc ccacuucucc     1020

uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg gcgaguaccg cggcaccccc     1080

cgcaaccagg accucuacga cgccgccaag gccuacgccg agcagcucaa ggagaacggc     1140

gucaucaacu acuccguccu cgaccucacc gccgaggagc ucgaggccau caagcaccag     1200

cucaacccca aggacaacga cgucgagcuc ugaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10194
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10194
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcccugagca aggugaaacu caacgacacc cuuaauaagg aucagcuguu guccucuuca      120

aaauacacaa uccaaagaag uacuggcgac agcauugaua cgcccaacua ugacguccag      180

aagcacauaa auaaauuaug cgggaugcug cuaaucaccg aggaugcuaa ccauaaguuc      240

acaggacuca uugguaugcu guacgcaaug uccaggcuug gccgggaaga cacuaucaag      300

auucugcgcg augccgggua ucacguuaaa gcgaauggag uggacguaac cacacaucga      360

caggauauca acggcaagga gaugaaauuu gaaguguuga cccucgcuuc ucugacuaca      420

gagauacaga ucaauauuga aaucgagucg cguaagucau acaaaaagau gcugaaggag      480

augggugaag ucgccccuga guauagacac gacagcccag auugugggau gauuauccuc      540

ugcauagcag ccuuagugau uaccaaacug gcugcaggag acaggagugg ccuuacggcc      600

guuauccggc gcgcuaacaa uguguugaag aacgaaauga aaagauacaa gggccugcua      660

ccgaaagaua uugccaauuc cuucuaugag gucuuugaga agcaucccca cuucaucgac      720

guguuuguac acuucgggau cgcgcaaucu agcacuaggg gagguucccg gguugaaggc      780

auuuuugcag gacucuucau gaacgccuac ggggcuggcc aggugaugcu gcgcuggggu      840

guccuugcca aaucagugaa gaauauaaug cuggggcaug caagugugca ggcugagaug      900

gaacaggucg uugaggugua cgaauaugcc caaaaguugg gaggcgaggc gggcuuuuac      960

cacauccuca acaauccuaa agccagccug uuaucucuga cccaguuccc acauuuuucc     1020

ucaguagugc ucgggaacgc agcuggacuu gguauuaugg gcgaguaucg agggacaccc     1080

agaaaccagg accuguacga ugccgcuaag gccuaugcag aacaguugaa agagaaugga     1140

gucaucaacu acagcgugcu agaccugacu gccgaggaac ucgaagcuau aaagcaccaa     1200

cugaauccua aagauaacga cguugagcuu ugaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10195
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10195
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcccugagca aggugaagcu gaacgacacc cugaacaagg accagcugcu gagcagcagc      120

aaguacacca uccagagaag caccggcgac agcaucgaca cccccaacua cgacgugcag      180

aagcacauca acaagcugug cggcaugcug cugaucaccg aggacgccaa ccacaaguuc      240

accggccuga ucggcaugcu guacgccaug agcagacugg gcagagagga caccaucaag      300

auccugagag acgccggcua ccacgugaag gccaacggcg uggacgugac cacccacaga      360

caggacauca acggcaagga gaugaaguuc gaggugcuga cccuggccag ccugaccacc      420

gagauccaga ucaacaucga gaucgagagc agaaagagcu acaagaagau gcugaaggag      480

augggcgagg uggcccccga guacagacac gacagccccg acugcggcau gaucauccug      540

ugcaucgccg cccuggugau caccaagcug gccgccggcg acagaagcgg ccugaccgcc      600

gugaucagaa gagccaacaa cgugcugaag aacgagauga agagauacaa gggccugcug      660

cccaaggaca ucgccaacag cuucuacgag guguucgaga agcaccccca cuucaucgac      720

guguucgugc acuucggcau cgcccagagc agcaccagag gcggcagcag aguggagggc      780

aucuucgccg gccuguucau gaacgccuac ggcgccggcc aggugaugcu gagauggggc      840

gugcuggcca agagcgugaa gaacaucaug cugggccacg ccagcgugca ggccgagaug      900

gagcaggugg uggaggugua cgaguacgcc cagaagcugg gcggcgaggc cggcuucuac      960

cacauccuga acaaccccaa ggccagccug cugagccuga cccaguuccc ccacuucagc     1020

agcguggugc ugggcaacgc cgccggccug ggcaucaugg gcgaguacag aggcaccccc     1080

agaaaccagg accuguacga cgccgccaag gccuacgccg agcagcugaa ggagaacggc     1140

gugaucaacu acagcgugcu ggaccugacc gccgaggagc uggaggccau caagcaccag     1200

cugaacccca aggacaacga cguggagcug ugaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10196
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10196
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcccugagca aggugaaacu caacgacacc cugaauaagg aucagcuucu guccucuagc      120

aaauacacaa uccaaagauc cacgggcgac ucuauugaua cccccaacua ugacguccag      180

aagcacauca auaaacucug cgggaugcug cuuauuacag aggaugcuaa ccauaaguuc      240

accggacuga ucggcaugcu cuacgccaug agccggcugg ggcgcgaaga cacaauuaag      300

auccugagag augcgggaua ucacguuaaa gcuaauggcg uggacgugac cacacaucgg      360

caggauauca acgggaagga gaugaaauuu gaaguccuca cccuggccuc ccuuacgacc      420

gagauucaga ucaauauuga aaucgagucu cgcaagagcu acaaaaagau gcugaaggag      480

augggagaag uggccccuga guauagacac gacuccccgg auuguggcau gauuauccuc      540

ugcauugcug cccugguuau cacaaaacuu gcugccggcg accggagcgg gcugaccgcg      600

gugauccgca gagccaacaa uguccucaag aacgaaauga aacgguacaa gggacugcug      660

cccaaagaua uugcuaauuc uuucuaugag guguuugaga agcauccuca cuucaucgac      720

guuuuugugc acuucggcau ugcccaaucc agcacacgcg ggggaucuag agucgaaggc      780

aucuuugcug gacucuucau gaacgccuac ggggcgggcc aggugaugcu gcgguggggc      840

gugcuugcca aauccgucaa gaauauuaug cuggggcaug cuagcguuca ggccgagaug      900

gaacaggugg uggaggucua cgaauaugcu caaaagcucg gaggcgaggc cggguuuuac      960

cacauccuga acaaucccaa agccucucuu cugucccuca cccaguuccc ucauuuuagc     1020

uccgugguuc ugggaaacgc ugcgggccug gggaucaugg gagaguaucg cggcacgccc     1080

agaaaccagg accucuacga ugccgcuaag gccuaugccg aacagcugaa agagaauggc     1140

gugauuaacu acucuguccu ugaccugaca gcugaggaac ucgaagccau caagcaccaa     1200

cugaauccua aagauaacga cguggagcuu ugaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10197
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10197
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcacuaagca aagucaaauu aaacgacaca uuaaacaaag accaacucuu aucaucauca      120

aaauacacaa uacaaagaag caccggagac aguaucgaca caccaaacua ugacguccaa      180

aaacauauaa auaaauuaug cggcaugcuc uuaaucacag aagacgccaa ccauaaauuu      240

acaggauuaa uaggaauguu auaugcaaug ucacgacuag guagagaaga cacaauaaaa      300

auacuaagag acgcaggcua ucacguaaaa gcaaauggag uagacguaac cacacacaga      360

caagacauaa auggaaaaga aaugaaauuu gaaguauuaa cacuagcauc acuaacaaca      420

gaaauacaaa ucaacauaga aauagaauca agaaaaagcu acaaaaaaau guuaaaagaa      480

augggagaag ucgcaccaga auauagacau gauucaccag acugcggaau gauaauacua      540

ugcauagcag cccuaguaau uacaaaacua gcagcaggag acagaagcgg auuaacagca      600

guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga aaagauauaa aggauuauua      660

ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa aacaccccca cuuuauagac      720

gucuucguac acuucggaau agcccaauca uccacaagag gaggaucaag agucgaagga      780

auauucgcag gauuauucau gaacgcauau ggcgcaggac aaguaaugcu aagaugggga      840

guacuagcaa aauccgucaa aaacauaaug cuaggacacg caucaguuca agcagaaaug      900

gaacaaguag uagaaguaua cgaauacgcc caaaaacuag gaggagaagc aggauucuac      960

cacauacuaa auaauccaaa agcaucacua cuaagccuaa cccaauuucc ccacuucuca     1020

aguguaguau uaggaaaugc agcuggacua ggaauaaugg gagaauacag aggaacacca     1080

agaaaccaag acuuauacga cgcagcaaaa gcauacgcag agcaacuuaa agaaaacgga     1140

guaauaaacu auagcguacu agacuuaaca gcagaagaac uggaagcaau aaaacaucaa     1200

uuaaacccga aagacaauga cguagaauua uaaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10198
<211>  1445
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10198
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gcacucucga aaguaaaacu caacgacacc cucaacaaag accaacuccu uuccagcucc      120

aaauacacca uccaacgauc caccggagac uccaucgaca cgcccaacua cgacguccag      180

aaacacauca acaagcucug cggaaugcua cuaaucaccg aggacgccaa ccacaaauuc      240

acaggacuua uagggaugcu cuacgccaug ucccgccucg gacgcgaaga cacaauaaaa      300

auccuacgag acgccggcua ccacguaaag gcaaacggcg ucgacgucac cacacacaga      360

caagacauca acggaaagga aaugaaauuc gaaguccuca cccucgccag ccuaaccacc      420

gagauccaaa ucaacaucga aaucgaauca cgcaaauccu acaagaaaau gcucaaagaa      480

augggagaag ucgcccccga auaccgucac gacucgcccg acugcggcau gauaauccua      540

ugcaucgccg cacucgucau aaccaaacuc gccgccggug accgaucagg acugacagca      600

gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga aacgcuacaa aggccuacuc      660

cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa aacacccaca cuucaucgac      720

gucuucgucc acuucggcau cgcacaauca ucaaccagag gcggcagccg cguugaaggc      780

aucuucgcag gacucuuuau gaacgccuac ggcgccggcc aagucaugcu ccgcuggggc      840

guccuggcaa aaagcgucaa aaacaucaug cuaggccacg cuagcgucca agccgaaaug      900

gaacaagucg ucgaaguuua cgaguacgca caaaaacucg gcggcgaagc aggcuucuac      960

cacauccuaa acaaccccaa agccucccug cuaucacuca cccaauuccc ccacuucucc     1020

agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg gagaauaccg cgggacaccg     1080

cgcaaccaag accucuacga cgccgccaaa gccuacgccg aacaacucaa agaaaacggc     1140

gucauaaacu acucaguccu cgaccucacc gccgaagaac ucgaagccau caaacaccaa     1200

cucaacccaa aagacaacga cgucgaauua uaaggacuag uguccaccug ucccuccugg     1260

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1440

gaauu                                                                 1445


<210>  10199
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10199
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucuuagca aagucaaguu gaaugauaca cucaacaaag      120

aucaacuucu gucauccagc aaauacacca uccaacggag cacaggagau aguauugaua      180

cuccuaauua ugaugugcag aaacacauca auaaguuaug uggcauguua uuaaucacag      240

aagaugcuaa ucauaaauuc acuggguuaa uagguauguu auaugcgaug ucuagguuag      300

gaagagaaga caccauaaaa auacucagag augcgggaua ucauguaaaa gcaaauggag      360

uagauguaac aacacaucgu caagacauua auggaaaaga aaugaaauuu gaaguguuaa      420

cauuggcaag cuuaacaacu gaaauucaaa ucaacauuga gauagaaucu agaaaauccu      480

acaaaaaaau gcuaaaagaa augggagagg uagcuccaga auacaggcau gacucuccug      540

auugugggau gauaauauua uguauagcag cauuaguaau aacuaaauua gcagcagggg      600

acagaucugg ucuuacagcc gugauuagga gagcuaauaa uguccuaaaa aaugaaauga      660

aacguuacaa aggcuuacua cccaaggaca uagccaacag cuucuaugaa guguuugaaa      720

aacaucccca cuuuauagau guuuuuguuc auuuugguau agcacaaucu ucuaccagag      780

guggcaguag aguugaaggg auuuuugcag gauuguuuau gaaugccuau ggugcagggc      840

aagugauguu acggugggga gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug      900

cuagugugca agcagaaaug gaacaaguug uugagguuua ugaauaugcc caaaaauugg      960

guggugaagc aggauucuac cauauauuga acaacccaaa agcaucauua uuaucuuuga     1020

cucaauuucc ucacuucucc aguguaguau uaggcaaugc ugcuggccua ggcauaaugg     1080

gagaguacag agguacaccg aggaaucaag aucuauauga ugcagcaaag gcauaugcug     1140

aacaacucaa agaaaauggu gugauuaacu acaguguacu agacuugaca gcagaagaac     1200

uagaggcuau caaacaucag cuuaauccaa aagauaauga uguagagcuu ugaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10200
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10200
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu caacgacacc cugaacaagg      120

accagcugcu cuccagcucc aaguacacca uccagcgcag caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcugug cgggaugcug cucaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucgggaugcu guacgcgaug agccggcucg      300

gccgcgagga cacgaucaag auccugcggg acgccgggua ccacgugaag gccaacggcg      360

uggacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccucgccuc ccugacgacc gagauccaga ucaacaucga gaucgagagc cggaaguccu      480

acaagaagau gcugaaggag augggggagg uggccccgga guaccgccac gacagccccg      540

acugcggcau gaucauccuc ugcaucgcgg cccuggucau caccaagcug gccgccgggg      600

accgguccgg ccucaccgcg gugauccgcc gggccaacaa cgugcugaag aacgagauga      660

agcgcuacaa ggggcugcuc cccaaggaca ucgccaacag cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagucc agcacgcggg      780

gcgggucccg cgucgagggc aucuucgccg ggcuguucau gaacgcguac ggcgccggcc      840

aggugaugcu gcgguggggc gugcucgcca agagcgucaa gaacaucaug cuggggcacg      900

ccuccgugca ggccgagaug gagcaggucg uggaggugua cgaguacgcg cagaagcucg      960

ggggcgaggc cggguucuac cacauccuga acaacccgaa ggccagccug cugucccuca     1020

cccaguuccc ccacuucagc agcguggucc ugggcaacgc cgccggccug gggaucaugg     1080

gcgaguaccg cgggacgccc cggaaccagg accucuacga cgcggccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acuccgugcu ggaccucacc gccgaggagc     1200

uggaggcgau caagcaccag cugaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10201
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10201
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccucucca aggucaagcu caacgacacc cucaacaagg      120

accagcuccu cuccuccucc aaguacacca uccagcgcuc caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcucug cggcaugcuc cucaucaccg      240

aggacgccaa ccacaaguuc accggccuca ucggcaugcu cuacgccaug ucccgccucg      300

gccgcgagga caccaucaag auccuccgcg acgccggcua ccacgucaag gccaacggcg      360

ucgacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gagguccuca      420

cccucgccuc ccucaccacc gagauccaga ucaacaucga gaucgagucc cgcaaguccu      480

acaagaagau gcucaaggag augggcgagg ucgcccccga guaccgccac gacucccccg      540

acugcggcau gaucauccuc ugcaucgccg cccucgucau caccaagcuc gccgccggcg      600

accgcuccgg ccucaccgcc gucauccgcc gcgccaacaa cguccucaag aacgagauga      660

agcgcuacaa gggccuccuc cccaaggaca ucgccaacuc cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac gucuucgucc acuucggcau cgcccagucc uccacccgcg      780

gcggcucccg cgucgagggc aucuucgccg gccucuucau gaacgccuac ggcgccggcc      840

aggucaugcu ccgcuggggc guccucgcca aguccgucaa gaacaucaug cucggccacg      900

ccuccgucca ggccgagaug gagcaggucg ucgaggucua cgaguacgcc cagaagcucg      960

gcggcgaggc cggcuucuac cacauccuca acaaccccaa ggccucccuc cucucccuca     1020

cccaguuccc ccacuucucc uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg     1080

gcgaguaccg cggcaccccc cgcaaccagg accucuacga cgccgccaag gccuacgccg     1140

agcagcucaa ggagaacggc gucaucaacu acuccguccu cgaccucacc gccgaggagc     1200

ucgaggccau caagcaccag cucaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10202
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10202
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cuuaauaagg      120

aucagcuguu guccucuuca aaauacacaa uccaaagaag uacuggcgac agcauugaua      180

cgcccaacua ugacguccag aagcacauaa auaaauuaug cgggaugcug cuaaucaccg      240

aggaugcuaa ccauaaguuc acaggacuca uugguaugcu guacgcaaug uccaggcuug      300

gccgggaaga cacuaucaag auucugcgcg augccgggua ucacguuaaa gcgaauggag      360

uggacguaac cacacaucga caggauauca acggcaagga gaugaaauuu gaaguguuga      420

cccucgcuuc ucugacuaca gagauacaga ucaauauuga aaucgagucg cguaagucau      480

acaaaaagau gcugaaggag augggugaag ucgccccuga guauagacac gacagcccag      540

auugugggau gauuauccuc ugcauagcag ccuuagugau uaccaaacug gcugcaggag      600

acaggagugg ccuuacggcc guuauccggc gcgcuaacaa uguguugaag aacgaaauga      660

aaagauacaa gggccugcua ccgaaagaua uugccaauuc cuucuaugag gucuuugaga      720

agcaucccca cuucaucgac guguuuguac acuucgggau cgcgcaaucu agcacuaggg      780

gagguucccg gguugaaggc auuuuugcag gacucuucau gaacgccuac ggggcuggcc      840

aggugaugcu gcgcuggggu guccuugcca aaucagugaa gaauauaaug cuggggcaug      900

caagugugca ggcugagaug gaacaggucg uugaggugua cgaauaugcc caaaaguugg      960

gaggcgaggc gggcuuuuac cacauccuca acaauccuaa agccagccug uuaucucuga     1020

cccaguuccc acauuuuucc ucaguagugc ucgggaacgc agcuggacuu gguauuaugg     1080

gcgaguaucg agggacaccc agaaaccagg accuguacga ugccgcuaag gccuaugcag     1140

aacaguugaa agagaaugga gucaucaacu acagcgugcu agaccugacu gccgaggaac     1200

ucgaagcuau aaagcaccaa cugaauccua aagauaacga cguugagcuu ugaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10203
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10203
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu gaacgacacc cugaacaagg      120

accagcugcu gagcagcagc aaguacacca uccagagaag caccggcgac agcaucgaca      180

cccccaacua cgacgugcag aagcacauca acaagcugug cggcaugcug cugaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucggcaugcu guacgccaug agcagacugg      300

gcagagagga caccaucaag auccugagag acgccggcua ccacgugaag gccaacggcg      360

uggacgugac cacccacaga caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccuggccag ccugaccacc gagauccaga ucaacaucga gaucgagagc agaaagagcu      480

acaagaagau gcugaaggag augggcgagg uggcccccga guacagacac gacagccccg      540

acugcggcau gaucauccug ugcaucgccg cccuggugau caccaagcug gccgccggcg      600

acagaagcgg ccugaccgcc gugaucagaa gagccaacaa cgugcugaag aacgagauga      660

agagauacaa gggccugcug cccaaggaca ucgccaacag cuucuacgag guguucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagagc agcaccagag      780

gcggcagcag aguggagggc aucuucgccg gccuguucau gaacgccuac ggcgccggcc      840

aggugaugcu gagauggggc gugcuggcca agagcgugaa gaacaucaug cugggccacg      900

ccagcgugca ggccgagaug gagcaggugg uggaggugua cgaguacgcc cagaagcugg      960

gcggcgaggc cggcuucuac cacauccuga acaaccccaa ggccagccug cugagccuga     1020

cccaguuccc ccacuucagc agcguggugc ugggcaacgc cgccggccug ggcaucaugg     1080

gcgaguacag aggcaccccc agaaaccagg accuguacga cgccgccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acagcgugcu ggaccugacc gccgaggagc     1200

uggaggccau caagcaccag cugaacccca aggacaacga cguggagcug ugaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10204
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10204
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cugaauaagg      120

aucagcuucu guccucuagc aaauacacaa uccaaagauc cacgggcgac ucuauugaua      180

cccccaacua ugacguccag aagcacauca auaaacucug cgggaugcug cuuauuacag      240

aggaugcuaa ccauaaguuc accggacuga ucggcaugcu cuacgccaug agccggcugg      300

ggcgcgaaga cacaauuaag auccugagag augcgggaua ucacguuaaa gcuaauggcg      360

uggacgugac cacacaucgg caggauauca acgggaagga gaugaaauuu gaaguccuca      420

cccuggccuc ccuuacgacc gagauucaga ucaauauuga aaucgagucu cgcaagagcu      480

acaaaaagau gcugaaggag augggagaag uggccccuga guauagacac gacuccccgg      540

auuguggcau gauuauccuc ugcauugcug cccugguuau cacaaaacuu gcugccggcg      600

accggagcgg gcugaccgcg gugauccgca gagccaacaa uguccucaag aacgaaauga      660

aacgguacaa gggacugcug cccaaagaua uugcuaauuc uuucuaugag guguuugaga      720

agcauccuca cuucaucgac guuuuugugc acuucggcau ugcccaaucc agcacacgcg      780

ggggaucuag agucgaaggc aucuuugcug gacucuucau gaacgccuac ggggcgggcc      840

aggugaugcu gcgguggggc gugcuugcca aauccgucaa gaauauuaug cuggggcaug      900

cuagcguuca ggccgagaug gaacaggugg uggaggucua cgaauaugcu caaaagcucg      960

gaggcgaggc cggguuuuac cacauccuga acaaucccaa agccucucuu cugucccuca     1020

cccaguuccc ucauuuuagc uccgugguuc ugggaaacgc ugcgggccug gggaucaugg     1080

gagaguaucg cggcacgccc agaaaccagg accucuacga ugccgcuaag gccuaugccg     1140

aacagcugaa agagaauggc gugauuaacu acucuguccu ugaccugaca gcugaggaac     1200

ucgaagccau caagcaccaa cugaauccua aagauaacga cguggagcuu ugaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10205
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10205
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaagca aagucaaauu aaacgacaca uuaaacaaag      120

accaacucuu aucaucauca aaauacacaa uacaaagaag caccggagac aguaucgaca      180

caccaaacua ugacguccaa aaacauauaa auaaauuaug cggcaugcuc uuaaucacag      240

aagacgccaa ccauaaauuu acaggauuaa uaggaauguu auaugcaaug ucacgacuag      300

guagagaaga cacaauaaaa auacuaagag acgcaggcua ucacguaaaa gcaaauggag      360

uagacguaac cacacacaga caagacauaa auggaaaaga aaugaaauuu gaaguauuaa      420

cacuagcauc acuaacaaca gaaauacaaa ucaacauaga aauagaauca agaaaaagcu      480

acaaaaaaau guuaaaagaa augggagaag ucgcaccaga auauagacau gauucaccag      540

acugcggaau gauaauacua ugcauagcag cccuaguaau uacaaaacua gcagcaggag      600

acagaagcgg auuaacagca guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga      660

aaagauauaa aggauuauua ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa      720

aacaccccca cuuuauagac gucuucguac acuucggaau agcccaauca uccacaagag      780

gaggaucaag agucgaagga auauucgcag gauuauucau gaacgcauau ggcgcaggac      840

aaguaaugcu aagaugggga guacuagcaa aauccgucaa aaacauaaug cuaggacacg      900

caucaguuca agcagaaaug gaacaaguag uagaaguaua cgaauacgcc caaaaacuag      960

gaggagaagc aggauucuac cacauacuaa auaauccaaa agcaucacua cuaagccuaa     1020

cccaauuucc ccacuucuca aguguaguau uaggaaaugc agcuggacua ggaauaaugg     1080

gagaauacag aggaacacca agaaaccaag acuuauacga cgcagcaaaa gcauacgcag     1140

agcaacuuaa agaaaacgga guaauaaacu auagcguacu agacuuaaca gcagaagaac     1200

uggaagcaau aaaacaucaa uuaaacccga aagacaauga cguagaauua uaaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10206
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10206
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacucucga aaguaaaacu caacgacacc cucaacaaag      120

accaacuccu uuccagcucc aaauacacca uccaacgauc caccggagac uccaucgaca      180

cgcccaacua cgacguccag aaacacauca acaagcucug cggaaugcua cuaaucaccg      240

aggacgccaa ccacaaauuc acaggacuua uagggaugcu cuacgccaug ucccgccucg      300

gacgcgaaga cacaauaaaa auccuacgag acgccggcua ccacguaaag gcaaacggcg      360

ucgacgucac cacacacaga caagacauca acggaaagga aaugaaauuc gaaguccuca      420

cccucgccag ccuaaccacc gagauccaaa ucaacaucga aaucgaauca cgcaaauccu      480

acaagaaaau gcucaaagaa augggagaag ucgcccccga auaccgucac gacucgcccg      540

acugcggcau gauaauccua ugcaucgccg cacucgucau aaccaaacuc gccgccggug      600

accgaucagg acugacagca gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga      660

aacgcuacaa aggccuacuc cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa      720

aacacccaca cuucaucgac gucuucgucc acuucggcau cgcacaauca ucaaccagag      780

gcggcagccg cguugaaggc aucuucgcag gacucuuuau gaacgccuac ggcgccggcc      840

aagucaugcu ccgcuggggc guccuggcaa aaagcgucaa aaacaucaug cuaggccacg      900

cuagcgucca agccgaaaug gaacaagucg ucgaaguuua cgaguacgca caaaaacucg      960

gcggcgaagc aggcuucuac cacauccuaa acaaccccaa agccucccug cuaucacuca     1020

cccaauuccc ccacuucucc agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg     1080

gagaauaccg cgggacaccg cgcaaccaag accucuacga cgccgccaaa gccuacgccg     1140

aacaacucaa agaaaacggc gucauaaacu acucaguccu cgaccucacc gccgaagaac     1200

ucgaagccau caaacaccaa cucaacccaa aagacaacga cgucgaauua uaaggacuag     1260

uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa uaaacaggau     1320

cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10207
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10207
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucuuagca aagucaaguu gaaugauaca cucaacaaag      120

aucaacuucu gucauccagc aaauacacca uccaacggag cacaggagau aguauugaua      180

cuccuaauua ugaugugcag aaacacauca auaaguuaug uggcauguua uuaaucacag      240

aagaugcuaa ucauaaauuc acuggguuaa uagguauguu auaugcgaug ucuagguuag      300

gaagagaaga caccauaaaa auacucagag augcgggaua ucauguaaaa gcaaauggag      360

uagauguaac aacacaucgu caagacauua auggaaaaga aaugaaauuu gaaguguuaa      420

cauuggcaag cuuaacaacu gaaauucaaa ucaacauuga gauagaaucu agaaaauccu      480

acaaaaaaau gcuaaaagaa augggagagg uagcuccaga auacaggcau gacucuccug      540

auugugggau gauaauauua uguauagcag cauuaguaau aacuaaauua gcagcagggg      600

acagaucugg ucuuacagcc gugauuagga gagcuaauaa uguccuaaaa aaugaaauga      660

aacguuacaa aggcuuacua cccaaggaca uagccaacag cuucuaugaa guguuugaaa      720

aacaucccca cuuuauagau guuuuuguuc auuuugguau agcacaaucu ucuaccagag      780

guggcaguag aguugaaggg auuuuugcag gauuguuuau gaaugccuau ggugcagggc      840

aagugauguu acggugggga gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug      900

cuagugugca agcagaaaug gaacaaguug uugagguuua ugaauaugcc caaaaauugg      960

guggugaagc aggauucuac cauauauuga acaacccaaa agcaucauua uuaucuuuga     1020

cucaauuucc ucacuucucc aguguaguau uaggcaaugc ugcuggccua ggcauaaugg     1080

gagaguacag agguacaccg aggaaucaag aucuauauga ugcagcaaag gcauaugcug     1140

aacaacucaa agaaaauggu gugauuaacu acaguguacu agacuugaca gcagaagaac     1200

uagaggcuau caaacaucag cuuaauccaa aagauaauga uguagagcuu ugaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10208
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10208
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu caacgacacc cugaacaagg      120

accagcugcu cuccagcucc aaguacacca uccagcgcag caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcugug cgggaugcug cucaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucgggaugcu guacgcgaug agccggcucg      300

gccgcgagga cacgaucaag auccugcggg acgccgggua ccacgugaag gccaacggcg      360

uggacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccucgccuc ccugacgacc gagauccaga ucaacaucga gaucgagagc cggaaguccu      480

acaagaagau gcugaaggag augggggagg uggccccgga guaccgccac gacagccccg      540

acugcggcau gaucauccuc ugcaucgcgg cccuggucau caccaagcug gccgccgggg      600

accgguccgg ccucaccgcg gugauccgcc gggccaacaa cgugcugaag aacgagauga      660

agcgcuacaa ggggcugcuc cccaaggaca ucgccaacag cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagucc agcacgcggg      780

gcgggucccg cgucgagggc aucuucgccg ggcuguucau gaacgcguac ggcgccggcc      840

aggugaugcu gcgguggggc gugcucgcca agagcgucaa gaacaucaug cuggggcacg      900

ccuccgugca ggccgagaug gagcaggucg uggaggugua cgaguacgcg cagaagcucg      960

ggggcgaggc cggguucuac cacauccuga acaacccgaa ggccagccug cugucccuca     1020

cccaguuccc ccacuucagc agcguggucc ugggcaacgc cgccggccug gggaucaugg     1080

gcgaguaccg cgggacgccc cggaaccagg accucuacga cgcggccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acuccgugcu ggaccucacc gccgaggagc     1200

uggaggcgau caagcaccag cugaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10209
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10209
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccucucca aggucaagcu caacgacacc cucaacaagg      120

accagcuccu cuccuccucc aaguacacca uccagcgcuc caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcucug cggcaugcuc cucaucaccg      240

aggacgccaa ccacaaguuc accggccuca ucggcaugcu cuacgccaug ucccgccucg      300

gccgcgagga caccaucaag auccuccgcg acgccggcua ccacgucaag gccaacggcg      360

ucgacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gagguccuca      420

cccucgccuc ccucaccacc gagauccaga ucaacaucga gaucgagucc cgcaaguccu      480

acaagaagau gcucaaggag augggcgagg ucgcccccga guaccgccac gacucccccg      540

acugcggcau gaucauccuc ugcaucgccg cccucgucau caccaagcuc gccgccggcg      600

accgcuccgg ccucaccgcc gucauccgcc gcgccaacaa cguccucaag aacgagauga      660

agcgcuacaa gggccuccuc cccaaggaca ucgccaacuc cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac gucuucgucc acuucggcau cgcccagucc uccacccgcg      780

gcggcucccg cgucgagggc aucuucgccg gccucuucau gaacgccuac ggcgccggcc      840

aggucaugcu ccgcuggggc guccucgcca aguccgucaa gaacaucaug cucggccacg      900

ccuccgucca ggccgagaug gagcaggucg ucgaggucua cgaguacgcc cagaagcucg      960

gcggcgaggc cggcuucuac cacauccuca acaaccccaa ggccucccuc cucucccuca     1020

cccaguuccc ccacuucucc uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg     1080

gcgaguaccg cggcaccccc cgcaaccagg accucuacga cgccgccaag gccuacgccg     1140

agcagcucaa ggagaacggc gucaucaacu acuccguccu cgaccucacc gccgaggagc     1200

ucgaggccau caagcaccag cucaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10210
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10210
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cuuaauaagg      120

aucagcuguu guccucuuca aaauacacaa uccaaagaag uacuggcgac agcauugaua      180

cgcccaacua ugacguccag aagcacauaa auaaauuaug cgggaugcug cuaaucaccg      240

aggaugcuaa ccauaaguuc acaggacuca uugguaugcu guacgcaaug uccaggcuug      300

gccgggaaga cacuaucaag auucugcgcg augccgggua ucacguuaaa gcgaauggag      360

uggacguaac cacacaucga caggauauca acggcaagga gaugaaauuu gaaguguuga      420

cccucgcuuc ucugacuaca gagauacaga ucaauauuga aaucgagucg cguaagucau      480

acaaaaagau gcugaaggag augggugaag ucgccccuga guauagacac gacagcccag      540

auugugggau gauuauccuc ugcauagcag ccuuagugau uaccaaacug gcugcaggag      600

acaggagugg ccuuacggcc guuauccggc gcgcuaacaa uguguugaag aacgaaauga      660

aaagauacaa gggccugcua ccgaaagaua uugccaauuc cuucuaugag gucuuugaga      720

agcaucccca cuucaucgac guguuuguac acuucgggau cgcgcaaucu agcacuaggg      780

gagguucccg gguugaaggc auuuuugcag gacucuucau gaacgccuac ggggcuggcc      840

aggugaugcu gcgcuggggu guccuugcca aaucagugaa gaauauaaug cuggggcaug      900

caagugugca ggcugagaug gaacaggucg uugaggugua cgaauaugcc caaaaguugg      960

gaggcgaggc gggcuuuuac cacauccuca acaauccuaa agccagccug uuaucucuga     1020

cccaguuccc acauuuuucc ucaguagugc ucgggaacgc agcuggacuu gguauuaugg     1080

gcgaguaucg agggacaccc agaaaccagg accuguacga ugccgcuaag gccuaugcag     1140

aacaguugaa agagaaugga gucaucaacu acagcgugcu agaccugacu gccgaggaac     1200

ucgaagcuau aaagcaccaa cugaauccua aagauaacga cguugagcuu ugaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10211
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10211
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu gaacgacacc cugaacaagg      120

accagcugcu gagcagcagc aaguacacca uccagagaag caccggcgac agcaucgaca      180

cccccaacua cgacgugcag aagcacauca acaagcugug cggcaugcug cugaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucggcaugcu guacgccaug agcagacugg      300

gcagagagga caccaucaag auccugagag acgccggcua ccacgugaag gccaacggcg      360

uggacgugac cacccacaga caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccuggccag ccugaccacc gagauccaga ucaacaucga gaucgagagc agaaagagcu      480

acaagaagau gcugaaggag augggcgagg uggcccccga guacagacac gacagccccg      540

acugcggcau gaucauccug ugcaucgccg cccuggugau caccaagcug gccgccggcg      600

acagaagcgg ccugaccgcc gugaucagaa gagccaacaa cgugcugaag aacgagauga      660

agagauacaa gggccugcug cccaaggaca ucgccaacag cuucuacgag guguucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagagc agcaccagag      780

gcggcagcag aguggagggc aucuucgccg gccuguucau gaacgccuac ggcgccggcc      840

aggugaugcu gagauggggc gugcuggcca agagcgugaa gaacaucaug cugggccacg      900

ccagcgugca ggccgagaug gagcaggugg uggaggugua cgaguacgcc cagaagcugg      960

gcggcgaggc cggcuucuac cacauccuga acaaccccaa ggccagccug cugagccuga     1020

cccaguuccc ccacuucagc agcguggugc ugggcaacgc cgccggccug ggcaucaugg     1080

gcgaguacag aggcaccccc agaaaccagg accuguacga cgccgccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acagcgugcu ggaccugacc gccgaggagc     1200

uggaggccau caagcaccag cugaacccca aggacaacga cguggagcug ugaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10212
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10212
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cugaauaagg      120

aucagcuucu guccucuagc aaauacacaa uccaaagauc cacgggcgac ucuauugaua      180

cccccaacua ugacguccag aagcacauca auaaacucug cgggaugcug cuuauuacag      240

aggaugcuaa ccauaaguuc accggacuga ucggcaugcu cuacgccaug agccggcugg      300

ggcgcgaaga cacaauuaag auccugagag augcgggaua ucacguuaaa gcuaauggcg      360

uggacgugac cacacaucgg caggauauca acgggaagga gaugaaauuu gaaguccuca      420

cccuggccuc ccuuacgacc gagauucaga ucaauauuga aaucgagucu cgcaagagcu      480

acaaaaagau gcugaaggag augggagaag uggccccuga guauagacac gacuccccgg      540

auuguggcau gauuauccuc ugcauugcug cccugguuau cacaaaacuu gcugccggcg      600

accggagcgg gcugaccgcg gugauccgca gagccaacaa uguccucaag aacgaaauga      660

aacgguacaa gggacugcug cccaaagaua uugcuaauuc uuucuaugag guguuugaga      720

agcauccuca cuucaucgac guuuuugugc acuucggcau ugcccaaucc agcacacgcg      780

ggggaucuag agucgaaggc aucuuugcug gacucuucau gaacgccuac ggggcgggcc      840

aggugaugcu gcgguggggc gugcuugcca aauccgucaa gaauauuaug cuggggcaug      900

cuagcguuca ggccgagaug gaacaggugg uggaggucua cgaauaugcu caaaagcucg      960

gaggcgaggc cggguuuuac cacauccuga acaaucccaa agccucucuu cugucccuca     1020

cccaguuccc ucauuuuagc uccgugguuc ugggaaacgc ugcgggccug gggaucaugg     1080

gagaguaucg cggcacgccc agaaaccagg accucuacga ugccgcuaag gccuaugccg     1140

aacagcugaa agagaauggc gugauuaacu acucuguccu ugaccugaca gcugaggaac     1200

ucgaagccau caagcaccaa cugaauccua aagauaacga cguggagcuu ugaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10213
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10213
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaagca aagucaaauu aaacgacaca uuaaacaaag      120

accaacucuu aucaucauca aaauacacaa uacaaagaag caccggagac aguaucgaca      180

caccaaacua ugacguccaa aaacauauaa auaaauuaug cggcaugcuc uuaaucacag      240

aagacgccaa ccauaaauuu acaggauuaa uaggaauguu auaugcaaug ucacgacuag      300

guagagaaga cacaauaaaa auacuaagag acgcaggcua ucacguaaaa gcaaauggag      360

uagacguaac cacacacaga caagacauaa auggaaaaga aaugaaauuu gaaguauuaa      420

cacuagcauc acuaacaaca gaaauacaaa ucaacauaga aauagaauca agaaaaagcu      480

acaaaaaaau guuaaaagaa augggagaag ucgcaccaga auauagacau gauucaccag      540

acugcggaau gauaauacua ugcauagcag cccuaguaau uacaaaacua gcagcaggag      600

acagaagcgg auuaacagca guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga      660

aaagauauaa aggauuauua ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa      720

aacaccccca cuuuauagac gucuucguac acuucggaau agcccaauca uccacaagag      780

gaggaucaag agucgaagga auauucgcag gauuauucau gaacgcauau ggcgcaggac      840

aaguaaugcu aagaugggga guacuagcaa aauccgucaa aaacauaaug cuaggacacg      900

caucaguuca agcagaaaug gaacaaguag uagaaguaua cgaauacgcc caaaaacuag      960

gaggagaagc aggauucuac cacauacuaa auaauccaaa agcaucacua cuaagccuaa     1020

cccaauuucc ccacuucuca aguguaguau uaggaaaugc agcuggacua ggaauaaugg     1080

gagaauacag aggaacacca agaaaccaag acuuauacga cgcagcaaaa gcauacgcag     1140

agcaacuuaa agaaaacgga guaauaaacu auagcguacu agacuuaaca gcagaagaac     1200

uggaagcaau aaaacaucaa uuaaacccga aagacaauga cguagaauua uaaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10214
<211>  1516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10214
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacucucga aaguaaaacu caacgacacc cucaacaaag      120

accaacuccu uuccagcucc aaauacacca uccaacgauc caccggagac uccaucgaca      180

cgcccaacua cgacguccag aaacacauca acaagcucug cggaaugcua cuaaucaccg      240

aggacgccaa ccacaaauuc acaggacuua uagggaugcu cuacgccaug ucccgccucg      300

gacgcgaaga cacaauaaaa auccuacgag acgccggcua ccacguaaag gcaaacggcg      360

ucgacgucac cacacacaga caagacauca acggaaagga aaugaaauuc gaaguccuca      420

cccucgccag ccuaaccacc gagauccaaa ucaacaucga aaucgaauca cgcaaauccu      480

acaagaaaau gcucaaagaa augggagaag ucgcccccga auaccgucac gacucgcccg      540

acugcggcau gauaauccua ugcaucgccg cacucgucau aaccaaacuc gccgccggug      600

accgaucagg acugacagca gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga      660

aacgcuacaa aggccuacuc cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa      720

aacacccaca cuucaucgac gucuucgucc acuucggcau cgcacaauca ucaaccagag      780

gcggcagccg cguugaaggc aucuucgcag gacucuuuau gaacgccuac ggcgccggcc      840

aagucaugcu ccgcuggggc guccuggcaa aaagcgucaa aaacaucaug cuaggccacg      900

cuagcgucca agccgaaaug gaacaagucg ucgaaguuua cgaguacgca caaaaacucg      960

gcggcgaagc aggcuucuac cacauccuaa acaaccccaa agccucccug cuaucacuca     1020

cccaauuccc ccacuucucc agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg     1080

gagaauaccg cgggacaccg cgcaaccaag accucuacga cgccgccaaa gccuacgccg     1140

aacaacucaa agaaaacggc gucauaaacu acucaguccu cgaccucacc gccgaagaac     1200

ucgaagccau caaacaccaa cucaacccaa aagacaacga cgucgaauua uaaggacuag     1260

uaauaaggaa acuguaugaa ugucuguggg caggaaguga agagauccuu cuguaaaggu     1320

uuuuggaauu augucugcug aauaauaaac uuuuuugaaa uaauaaaucu gguagaaaaa     1380

ugagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1500

cagagccacc agaauu                                                     1516


<210>  10215
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10215
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcuc uuagcaaagu caaguugaau gauacacuca acaaagauca acuucuguca      180

uccagcaaau acaccaucca acggagcaca ggagauagua uugauacucc uaauuaugau      240

gugcagaaac acaucaauaa guuauguggc auguuauuaa ucacagaaga ugcuaaucau      300

aaauucacug gguuaauagg uauguuauau gcgaugucua gguuaggaag agaagacacc      360

auaaaaauac ucagagaugc gggauaucau guaaaagcaa auggaguaga uguaacaaca      420

caucgucaag acauuaaugg aaaagaaaug aaauuugaag uguuaacauu ggcaagcuua      480

acaacugaaa uucaaaucaa cauugagaua gaaucuagaa aauccuacaa aaaaaugcua      540

aaagaaaugg gagagguagc uccagaauac aggcaugacu cuccugauug ugggaugaua      600

auauuaugua uagcagcauu aguaauaacu aaauuagcag caggggacag aucuggucuu      660

acagccguga uuaggagagc uaauaauguc cuaaaaaaug aaaugaaacg uuacaaaggc      720

uuacuaccca aggacauagc caacagcuuc uaugaagugu uugaaaaaca uccccacuuu      780

auagauguuu uuguucauuu ugguauagca caaucuucua ccagaggugg caguagaguu      840

gaagggauuu uugcaggauu guuuaugaau gccuauggug cagggcaagu gauguuacgg      900

uggggagucu uagcaaaauc aguuaaaaau auuauguuag gacaugcuag ugugcaagca      960

gaaauggaac aaguuguuga gguuuaugaa uaugcccaaa aauugggugg ugaagcagga     1020

uucuaccaua uauugaacaa cccaaaagca ucauuauuau cuuugacuca auuuccucac     1080

uucuccagug uaguauuagg caaugcugcu ggccuaggca uaaugggaga guacagaggu     1140

acaccgagga aucaagaucu auaugaugca gcaaaggcau augcugaaca acucaaagaa     1200

aaugguguga uuaacuacag uguacuagac uugacagcag aagaacuaga ggcuaucaaa     1260

caucagcuua auccaaaaga uaaugaugua gagcuuugag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10216
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10216
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcucaac gacacccuga acaaggacca gcugcucucc      180

agcuccaagu acaccaucca gcgcagcacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcugugcggg augcugcuca ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg gaugcuguac gcgaugagcc ggcucggccg cgaggacacg      360

aucaagaucc ugcgggacgc cggguaccac gugaaggcca acggcgugga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg ugcugacccu cgccucccug      480

acgaccgaga uccagaucaa caucgagauc gagagccgga aguccuacaa gaagaugcug      540

aaggagaugg gggagguggc cccggaguac cgccacgaca gccccgacug cggcaugauc      600

auccucugca ucgcggcccu ggucaucacc aagcuggccg ccggggaccg guccggccuc      660

accgcgguga uccgccgggc caacaacgug cugaagaacg agaugaagcg cuacaagggg      720

cugcucccca aggacaucgc caacagcuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc caguccagca cgcggggcgg gucccgcguc      840

gagggcaucu ucgccgggcu guucaugaac gcguacggcg ccggccaggu gaugcugcgg      900

uggggcgugc ucgccaagag cgucaagaac aucaugcugg ggcacgccuc cgugcaggcc      960

gagauggagc aggucgugga gguguacgag uacgcgcaga agcucggggg cgaggccggg     1020

uucuaccaca uccugaacaa cccgaaggcc agccugcugu cccucaccca guucccccac     1080

uucagcagcg ugguccuggg caacgccgcc ggccugggga ucaugggcga guaccgcggg     1140

acgccccgga accaggaccu cuacgacgcg gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacuc cgugcuggac cucaccgccg aggagcugga ggcgaucaag     1260

caccagcuga accccaagga caacgacguc gagcucugag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10217
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10217
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ucuccaaggu caagcucaac gacacccuca acaaggacca gcuccucucc      180

uccuccaagu acaccaucca gcgcuccacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcucugcggc augcuccuca ucaccgagga cgccaaccac      300

aaguucaccg gccucaucgg caugcucuac gccauguccc gccucggccg cgaggacacc      360

aucaagaucc uccgcgacgc cggcuaccac gucaaggcca acggcgucga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg uccucacccu cgccucccuc      480

accaccgaga uccagaucaa caucgagauc gagucccgca aguccuacaa gaagaugcuc      540

aaggagaugg gcgaggucgc ccccgaguac cgccacgacu cccccgacug cggcaugauc      600

auccucugca ucgccgcccu cgucaucacc aagcucgccg ccggcgaccg cuccggccuc      660

accgccguca uccgccgcgc caacaacguc cucaagaacg agaugaagcg cuacaagggc      720

cuccucccca aggacaucgc caacuccuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgucu ucguccacuu cggcaucgcc caguccucca cccgcggcgg cucccgcguc      840

gagggcaucu ucgccggccu cuucaugaac gccuacggcg ccggccaggu caugcuccgc      900

uggggcgucc ucgccaaguc cgucaagaac aucaugcucg gccacgccuc cguccaggcc      960

gagauggagc aggucgucga ggucuacgag uacgcccaga agcucggcgg cgaggccggc     1020

uucuaccaca uccucaacaa ccccaaggcc ucccuccucu cccucaccca guucccccac     1080

uucuccuccg ucguccucgg caacgccgcc ggccucggca ucaugggcga guaccgcggc     1140

accccccgca accaggaccu cuacgacgcc gccaaggccu acgccgagca gcucaaggag     1200

aacggcguca ucaacuacuc cguccucgac cucaccgccg aggagcucga ggccaucaag     1260

caccagcuca accccaagga caacgacguc gagcucugag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10218
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10218
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuua auaaggauca gcuguugucc      180

ucuucaaaau acacaaucca aagaaguacu ggcgacagca uugauacgcc caacuaugac      240

guccagaagc acauaaauaa auuaugcggg augcugcuaa ucaccgagga ugcuaaccau      300

aaguucacag gacucauugg uaugcuguac gcaaugucca ggcuuggccg ggaagacacu      360

aucaagauuc ugcgcgaugc cggguaucac guuaaagcga auggagugga cguaaccaca      420

caucgacagg auaucaacgg caaggagaug aaauuugaag uguugacccu cgcuucucug      480

acuacagaga uacagaucaa uauugaaauc gagucgcgua agucauacaa aaagaugcug      540

aaggagaugg gugaagucgc cccugaguau agacacgaca gcccagauug ugggaugauu      600

auccucugca uagcagccuu agugauuacc aaacuggcug caggagacag gaguggccuu      660

acggccguua uccggcgcgc uaacaaugug uugaagaacg aaaugaaaag auacaagggc      720

cugcuaccga aagauauugc caauuccuuc uaugaggucu uugagaagca uccccacuuc      780

aucgacgugu uuguacacuu cgggaucgcg caaucuagca cuaggggagg uucccggguu      840

gaaggcauuu uugcaggacu cuucaugaac gccuacgggg cuggccaggu gaugcugcgc      900

uggggugucc uugccaaauc agugaagaau auaaugcugg ggcaugcaag ugugcaggcu      960

gagauggaac aggucguuga gguguacgaa uaugcccaaa aguugggagg cgaggcgggc     1020

uuuuaccaca uccucaacaa uccuaaagcc agccuguuau cucugaccca guucccacau     1080

uuuuccucag uagugcucgg gaacgcagcu ggacuuggua uuaugggcga guaucgaggg     1140

acacccagaa accaggaccu guacgaugcc gcuaaggccu augcagaaca guugaaagag     1200

aauggaguca ucaacuacag cgugcuagac cugacugccg aggaacucga agcuauaaag     1260

caccaacuga auccuaaaga uaacgacguu gagcuuugag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10219
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10219
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcugaac gacacccuga acaaggacca gcugcugagc      180

agcagcaagu acaccaucca gagaagcacc ggcgacagca ucgacacccc caacuacgac      240

gugcagaagc acaucaacaa gcugugcggc augcugcuga ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg caugcuguac gccaugagca gacugggcag agaggacacc      360

aucaagaucc ugagagacgc cggcuaccac gugaaggcca acggcgugga cgugaccacc      420

cacagacagg acaucaacgg caaggagaug aaguucgagg ugcugacccu ggccagccug      480

accaccgaga uccagaucaa caucgagauc gagagcagaa agagcuacaa gaagaugcug      540

aaggagaugg gcgagguggc ccccgaguac agacacgaca gccccgacug cggcaugauc      600

auccugugca ucgccgcccu ggugaucacc aagcuggccg ccggcgacag aagcggccug      660

accgccguga ucagaagagc caacaacgug cugaagaacg agaugaagag auacaagggc      720

cugcugccca aggacaucgc caacagcuuc uacgaggugu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc cagagcagca ccagaggcgg cagcagagug      840

gagggcaucu ucgccggccu guucaugaac gccuacggcg ccggccaggu gaugcugaga      900

uggggcgugc uggccaagag cgugaagaac aucaugcugg gccacgccag cgugcaggcc      960

gagauggagc agguggugga gguguacgag uacgcccaga agcugggcgg cgaggccggc     1020

uucuaccaca uccugaacaa ccccaaggcc agccugcuga gccugaccca guucccccac     1080

uucagcagcg uggugcuggg caacgccgcc ggccugggca ucaugggcga guacagaggc     1140

acccccagaa accaggaccu guacgacgcc gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacag cgugcuggac cugaccgccg aggagcugga ggccaucaag     1260

caccagcuga accccaagga caacgacgug gagcugugag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10220
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10220
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuga auaaggauca gcuucugucc      180

ucuagcaaau acacaaucca aagauccacg ggcgacucua uugauacccc caacuaugac      240

guccagaagc acaucaauaa acucugcggg augcugcuua uuacagagga ugcuaaccau      300

aaguucaccg gacugaucgg caugcucuac gccaugagcc ggcuggggcg cgaagacaca      360

auuaagaucc ugagagaugc gggauaucac guuaaagcua auggcgugga cgugaccaca      420

caucggcagg auaucaacgg gaaggagaug aaauuugaag uccucacccu ggccucccuu      480

acgaccgaga uucagaucaa uauugaaauc gagucucgca agagcuacaa aaagaugcug      540

aaggagaugg gagaaguggc cccugaguau agacacgacu ccccggauug uggcaugauu      600

auccucugca uugcugcccu gguuaucaca aaacuugcug ccggcgaccg gagcgggcug      660

accgcgguga uccgcagagc caacaauguc cucaagaacg aaaugaaacg guacaaggga      720

cugcugccca aagauauugc uaauucuuuc uaugaggugu uugagaagca uccucacuuc      780

aucgacguuu uugugcacuu cggcauugcc caauccagca cacgcggggg aucuagaguc      840

gaaggcaucu uugcuggacu cuucaugaac gccuacgggg cgggccaggu gaugcugcgg      900

uggggcgugc uugccaaauc cgucaagaau auuaugcugg ggcaugcuag cguucaggcc      960

gagauggaac agguggugga ggucuacgaa uaugcucaaa agcucggagg cgaggccggg     1020

uuuuaccaca uccugaacaa ucccaaagcc ucucuucugu cccucaccca guucccucau     1080

uuuagcuccg ugguucuggg aaacgcugcg ggccugggga ucaugggaga guaucgcggc     1140

acgcccagaa accaggaccu cuacgaugcc gcuaaggccu augccgaaca gcugaaagag     1200

aauggcguga uuaacuacuc uguccuugac cugacagcug aggaacucga agccaucaag     1260

caccaacuga auccuaaaga uaacgacgug gagcuuugag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10221
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10221
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac uaagcaaagu caaauuaaac gacacauuaa acaaagacca acucuuauca      180

ucaucaaaau acacaauaca aagaagcacc ggagacagua ucgacacacc aaacuaugac      240

guccaaaaac auauaaauaa auuaugcggc augcucuuaa ucacagaaga cgccaaccau      300

aaauuuacag gauuaauagg aauguuauau gcaaugucac gacuagguag agaagacaca      360

auaaaaauac uaagagacgc aggcuaucac guaaaagcaa auggaguaga cguaaccaca      420

cacagacaag acauaaaugg aaaagaaaug aaauuugaag uauuaacacu agcaucacua      480

acaacagaaa uacaaaucaa cauagaaaua gaaucaagaa aaagcuacaa aaaaauguua      540

aaagaaaugg gagaagucgc accagaauau agacaugauu caccagacug cggaaugaua      600

auacuaugca uagcagcccu aguaauuaca aaacuagcag caggagacag aagcggauua      660

acagcaguaa uaagaagagc aaacaacgua cuaaaaaacg aaaugaaaag auauaaagga      720

uuauuaccaa aagacauagc aaacucauuc uaugaaguau ucgaaaaaca cccccacuuu      780

auagacgucu ucguacacuu cggaauagcc caaucaucca caagaggagg aucaagaguc      840

gaaggaauau ucgcaggauu auucaugaac gcauauggcg caggacaagu aaugcuaaga      900

uggggaguac uagcaaaauc cgucaaaaac auaaugcuag gacacgcauc aguucaagca      960

gaaauggaac aaguaguaga aguauacgaa uacgcccaaa aacuaggagg agaagcagga     1020

uucuaccaca uacuaaauaa uccaaaagca ucacuacuaa gccuaaccca auuuccccac     1080

uucucaagug uaguauuagg aaaugcagcu ggacuaggaa uaaugggaga auacagagga     1140

acaccaagaa accaagacuu auacgacgca gcaaaagcau acgcagagca acuuaaagaa     1200

aacggaguaa uaaacuauag cguacuagac uuaacagcag aagaacugga agcaauaaaa     1260

caucaauuaa acccgaaaga caaugacgua gaauuauaag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10222
<211>  1578
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10222
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac ucucgaaagu aaaacucaac gacacccuca acaaagacca acuccuuucc      180

agcuccaaau acaccaucca acgauccacc ggagacucca ucgacacgcc caacuacgac      240

guccagaaac acaucaacaa gcucugcgga augcuacuaa ucaccgagga cgccaaccac      300

aaauucacag gacuuauagg gaugcucuac gccauguccc gccucggacg cgaagacaca      360

auaaaaaucc uacgagacgc cggcuaccac guaaaggcaa acggcgucga cgucaccaca      420

cacagacaag acaucaacgg aaaggaaaug aaauucgaag uccucacccu cgccagccua      480

accaccgaga uccaaaucaa caucgaaauc gaaucacgca aauccuacaa gaaaaugcuc      540

aaagaaaugg gagaagucgc ccccgaauac cgucacgacu cgcccgacug cggcaugaua      600

auccuaugca ucgccgcacu cgucauaacc aaacucgccg ccggugaccg aucaggacug      660

acagcaguca uccgccgagc aaacaacgug cucaaaaacg aaaugaaacg cuacaaaggc      720

cuacucccca aagacaucgc caacuccuuc uacgaagucu ucgaaaaaca cccacacuuc      780

aucgacgucu ucguccacuu cggcaucgca caaucaucaa ccagaggcgg cagccgcguu      840

gaaggcaucu ucgcaggacu cuuuaugaac gccuacggcg ccggccaagu caugcuccgc      900

uggggcgucc uggcaaaaag cgucaaaaac aucaugcuag gccacgcuag cguccaagcc      960

gaaauggaac aagucgucga aguuuacgag uacgcacaaa aacucggcgg cgaagcaggc     1020

uucuaccaca uccuaaacaa ccccaaagcc ucccugcuau cacucaccca auucccccac     1080

uucuccagcg ucguccucgg caacgccgca ggacuaggca ucaugggaga auaccgcggg     1140

acaccgcgca accaagaccu cuacgacgcc gccaaagccu acgccgaaca acucaaagaa     1200

aacggcguca uaaacuacuc aguccucgac cucaccgccg aagaacucga agccaucaaa     1260

caccaacuca acccaaaaga caacgacguc gaauuauaag gacuaguacu ggcugcaucu     1320

cccuuuccuc uguccuccau ccuucuccca ggauggugaa gggggaccug guacccagug     1380

auccccaccc caggauccua aaucaugacu uaccugcuaa uaaaaacuca uuggaaaagu     1440

gagaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1560

uucagagcca ccagaauu                                                   1578


<210>  10223
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10223
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cucuuagcaa agucaaguug      120

aaugauacac ucaacaaaga ucaacuucug ucauccagca aauacaccau ccaacggagc      180

acaggagaua guauugauac uccuaauuau gaugugcaga aacacaucaa uaaguuaugu      240

ggcauguuau uaaucacaga agaugcuaau cauaaauuca cuggguuaau agguauguua      300

uaugcgaugu cuagguuagg aagagaagac accauaaaaa uacucagaga ugcgggauau      360

cauguaaaag caaauggagu agauguaaca acacaucguc aagacauuaa uggaaaagaa      420

augaaauuug aaguguuaac auuggcaagc uuaacaacug aaauucaaau caacauugag      480

auagaaucua gaaaauccua caaaaaaaug cuaaaagaaa ugggagaggu agcuccagaa      540

uacaggcaug acucuccuga uugugggaug auaauauuau guauagcagc auuaguaaua      600

acuaaauuag cagcagggga cagaucuggu cuuacagccg ugauuaggag agcuaauaau      660

guccuaaaaa augaaaugaa acguuacaaa ggcuuacuac ccaaggacau agccaacagc      720

uucuaugaag uguuugaaaa acauccccac uuuauagaug uuuuuguuca uuuugguaua      780

gcacaaucuu cuaccagagg uggcaguaga guugaaggga uuuuugcagg auuguuuaug      840

aaugccuaug gugcagggca agugauguua cgguggggag ucuuagcaaa aucaguuaaa      900

aauauuaugu uaggacaugc uagugugcaa gcagaaaugg aacaaguugu ugagguuuau      960

gaauaugccc aaaaauuggg uggugaagca ggauucuacc auauauugaa caacccaaaa     1020

gcaucauuau uaucuuugac ucaauuuccu cacuucucca guguaguauu aggcaaugcu     1080

gcuggccuag gcauaauggg agaguacaga gguacaccga ggaaucaaga ucuauaugau     1140

gcagcaaagg cauaugcuga acaacucaaa gaaaauggug ugauuaacua caguguacua     1200

gacuugacag cagaagaacu agaggcuauc aaacaucagc uuaauccaaa agauaaugau     1260

guagagcuuu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10224
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10224
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcuc      120

aacgacaccc ugaacaagga ccagcugcuc uccagcucca aguacaccau ccagcgcagc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcugugc      240

gggaugcugc ucaucaccga ggacgccaac cacaaguuca ccggccugau cgggaugcug      300

uacgcgauga gccggcucgg ccgcgaggac acgaucaaga uccugcggga cgccggguac      360

cacgugaagg ccaacggcgu ggacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccucgccucc cugacgaccg agauccagau caacaucgag      480

aucgagagcc ggaaguccua caagaagaug cugaaggaga ugggggaggu ggccccggag      540

uaccgccacg acagccccga cugcggcaug aucauccucu gcaucgcggc ccuggucauc      600

accaagcugg ccgccgggga ccgguccggc cucaccgcgg ugauccgccg ggccaacaac      660

gugcugaaga acgagaugaa gcgcuacaag gggcugcucc ccaaggacau cgccaacagc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagucca gcacgcgggg cgggucccgc gucgagggca ucuucgccgg gcuguucaug      840

aacgcguacg gcgccggcca ggugaugcug cgguggggcg ugcucgccaa gagcgucaag      900

aacaucaugc uggggcacgc cuccgugcag gccgagaugg agcaggucgu ggagguguac      960

gaguacgcgc agaagcucgg gggcgaggcc ggguucuacc acauccugaa caacccgaag     1020

gccagccugc ugucccucac ccaguucccc cacuucagca gcgugguccu gggcaacgcc     1080

gccggccugg ggaucauggg cgaguaccgc gggacgcccc ggaaccagga ccucuacgac     1140

gcggccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cuccgugcug     1200

gaccucaccg ccgaggagcu ggaggcgauc aagcaccagc ugaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10225
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10225
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccucuccaa ggucaagcuc      120

aacgacaccc ucaacaagga ccagcuccuc uccuccucca aguacaccau ccagcgcucc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcucugc      240

ggcaugcucc ucaucaccga ggacgccaac cacaaguuca ccggccucau cggcaugcuc      300

uacgccaugu cccgccucgg ccgcgaggac accaucaaga uccuccgcga cgccggcuac      360

cacgucaagg ccaacggcgu cgacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg agguccucac ccucgccucc cucaccaccg agauccagau caacaucgag      480

aucgaguccc gcaaguccua caagaagaug cucaaggaga ugggcgaggu cgcccccgag      540

uaccgccacg acucccccga cugcggcaug aucauccucu gcaucgccgc ccucgucauc      600

accaagcucg ccgccggcga ccgcuccggc cucaccgccg ucauccgccg cgccaacaac      660

guccucaaga acgagaugaa gcgcuacaag ggccuccucc ccaaggacau cgccaacucc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg ucuucgucca cuucggcauc      780

gcccaguccu ccacccgcgg cggcucccgc gucgagggca ucuucgccgg ccucuucaug      840

aacgccuacg gcgccggcca ggucaugcuc cgcuggggcg uccucgccaa guccgucaag      900

aacaucaugc ucggccacgc cuccguccag gccgagaugg agcaggucgu cgaggucuac      960

gaguacgccc agaagcucgg cggcgaggcc ggcuucuacc acauccucaa caaccccaag     1020

gccucccucc ucucccucac ccaguucccc cacuucuccu ccgucguccu cggcaacgcc     1080

gccggccucg gcaucauggg cgaguaccgc ggcacccccc gcaaccagga ccucuacgac     1140

gccgccaagg ccuacgccga gcagcucaag gagaacggcg ucaucaacua cuccguccuc     1200

gaccucaccg ccgaggagcu cgaggccauc aagcaccagc ucaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10226
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10226
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc uuaauaagga ucagcuguug uccucuucaa aauacacaau ccaaagaagu      180

acuggcgaca gcauugauac gcccaacuau gacguccaga agcacauaaa uaaauuaugc      240

gggaugcugc uaaucaccga ggaugcuaac cauaaguuca caggacucau ugguaugcug      300

uacgcaaugu ccaggcuugg ccgggaagac acuaucaaga uucugcgcga ugccggguau      360

cacguuaaag cgaauggagu ggacguaacc acacaucgac aggauaucaa cggcaaggag      420

augaaauuug aaguguugac ccucgcuucu cugacuacag agauacagau caauauugaa      480

aucgagucgc guaagucaua caaaaagaug cugaaggaga ugggugaagu cgccccugag      540

uauagacacg acagcccaga uugugggaug auuauccucu gcauagcagc cuuagugauu      600

accaaacugg cugcaggaga caggaguggc cuuacggccg uuauccggcg cgcuaacaau      660

guguugaaga acgaaaugaa aagauacaag ggccugcuac cgaaagauau ugccaauucc      720

uucuaugagg ucuuugagaa gcauccccac uucaucgacg uguuuguaca cuucgggauc      780

gcgcaaucua gcacuagggg agguucccgg guugaaggca uuuuugcagg acucuucaug      840

aacgccuacg gggcuggcca ggugaugcug cgcuggggug uccuugccaa aucagugaag      900

aauauaaugc uggggcaugc aagugugcag gcugagaugg aacaggucgu ugagguguac      960

gaauaugccc aaaaguuggg aggcgaggcg ggcuuuuacc acauccucaa caauccuaaa     1020

gccagccugu uaucucugac ccaguuccca cauuuuuccu caguagugcu cgggaacgca     1080

gcuggacuug guauuauggg cgaguaucga gggacaccca gaaaccagga ccuguacgau     1140

gccgcuaagg ccuaugcaga acaguugaaa gagaauggag ucaucaacua cagcgugcua     1200

gaccugacug ccgaggaacu cgaagcuaua aagcaccaac ugaauccuaa agauaacgac     1260

guugagcuuu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10227
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10227
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcug      120

aacgacaccc ugaacaagga ccagcugcug agcagcagca aguacaccau ccagagaagc      180

accggcgaca gcaucgacac ccccaacuac gacgugcaga agcacaucaa caagcugugc      240

ggcaugcugc ugaucaccga ggacgccaac cacaaguuca ccggccugau cggcaugcug      300

uacgccauga gcagacuggg cagagaggac accaucaaga uccugagaga cgccggcuac      360

cacgugaagg ccaacggcgu ggacgugacc acccacagac aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccuggccagc cugaccaccg agauccagau caacaucgag      480

aucgagagca gaaagagcua caagaagaug cugaaggaga ugggcgaggu ggcccccgag      540

uacagacacg acagccccga cugcggcaug aucauccugu gcaucgccgc ccuggugauc      600

accaagcugg ccgccggcga cagaagcggc cugaccgccg ugaucagaag agccaacaac      660

gugcugaaga acgagaugaa gagauacaag ggccugcugc ccaaggacau cgccaacagc      720

uucuacgagg uguucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagagca gcaccagagg cggcagcaga guggagggca ucuucgccgg ccuguucaug      840

aacgccuacg gcgccggcca ggugaugcug agauggggcg ugcuggccaa gagcgugaag      900

aacaucaugc ugggccacgc cagcgugcag gccgagaugg agcagguggu ggagguguac      960

gaguacgccc agaagcuggg cggcgaggcc ggcuucuacc acauccugaa caaccccaag     1020

gccagccugc ugagccugac ccaguucccc cacuucagca gcguggugcu gggcaacgcc     1080

gccggccugg gcaucauggg cgaguacaga ggcaccccca gaaaccagga ccuguacgac     1140

gccgccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cagcgugcug     1200

gaccugaccg ccgaggagcu ggaggccauc aagcaccagc ugaaccccaa ggacaacgac     1260

guggagcugu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10228
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10228
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc ugaauaagga ucagcuucug uccucuagca aauacacaau ccaaagaucc      180

acgggcgacu cuauugauac ccccaacuau gacguccaga agcacaucaa uaaacucugc      240

gggaugcugc uuauuacaga ggaugcuaac cauaaguuca ccggacugau cggcaugcuc      300

uacgccauga gccggcuggg gcgcgaagac acaauuaaga uccugagaga ugcgggauau      360

cacguuaaag cuaauggcgu ggacgugacc acacaucggc aggauaucaa cgggaaggag      420

augaaauuug aaguccucac ccuggccucc cuuacgaccg agauucagau caauauugaa      480

aucgagucuc gcaagagcua caaaaagaug cugaaggaga ugggagaagu ggccccugag      540

uauagacacg acuccccgga uuguggcaug auuauccucu gcauugcugc ccugguuauc      600

acaaaacuug cugccggcga ccggagcggg cugaccgcgg ugauccgcag agccaacaau      660

guccucaaga acgaaaugaa acgguacaag ggacugcugc ccaaagauau ugcuaauucu      720

uucuaugagg uguuugagaa gcauccucac uucaucgacg uuuuugugca cuucggcauu      780

gcccaaucca gcacacgcgg gggaucuaga gucgaaggca ucuuugcugg acucuucaug      840

aacgccuacg gggcgggcca ggugaugcug cgguggggcg ugcuugccaa auccgucaag      900

aauauuaugc uggggcaugc uagcguucag gccgagaugg aacagguggu ggaggucuac      960

gaauaugcuc aaaagcucgg aggcgaggcc ggguuuuacc acauccugaa caaucccaaa     1020

gccucucuuc ugucccucac ccaguucccu cauuuuagcu ccgugguucu gggaaacgcu     1080

gcgggccugg ggaucauggg agaguaucgc ggcacgccca gaaaccagga ccucuacgau     1140

gccgcuaagg ccuaugccga acagcugaaa gagaauggcg ugauuaacua cucuguccuu     1200

gaccugacag cugaggaacu cgaagccauc aagcaccaac ugaauccuaa agauaacgac     1260

guggagcuuu gaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10229
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10229
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacuaagcaa agucaaauua      120

aacgacacau uaaacaaaga ccaacucuua ucaucaucaa aauacacaau acaaagaagc      180

accggagaca guaucgacac accaaacuau gacguccaaa aacauauaaa uaaauuaugc      240

ggcaugcucu uaaucacaga agacgccaac cauaaauuua caggauuaau aggaauguua      300

uaugcaaugu cacgacuagg uagagaagac acaauaaaaa uacuaagaga cgcaggcuau      360

cacguaaaag caaauggagu agacguaacc acacacagac aagacauaaa uggaaaagaa      420

augaaauuug aaguauuaac acuagcauca cuaacaacag aaauacaaau caacauagaa      480

auagaaucaa gaaaaagcua caaaaaaaug uuaaaagaaa ugggagaagu cgcaccagaa      540

uauagacaug auucaccaga cugcggaaug auaauacuau gcauagcagc ccuaguaauu      600

acaaaacuag cagcaggaga cagaagcgga uuaacagcag uaauaagaag agcaaacaac      660

guacuaaaaa acgaaaugaa aagauauaaa ggauuauuac caaaagacau agcaaacuca      720

uucuaugaag uauucgaaaa acacccccac uuuauagacg ucuucguaca cuucggaaua      780

gcccaaucau ccacaagagg aggaucaaga gucgaaggaa uauucgcagg auuauucaug      840

aacgcauaug gcgcaggaca aguaaugcua agauggggag uacuagcaaa auccgucaaa      900

aacauaaugc uaggacacgc aucaguucaa gcagaaaugg aacaaguagu agaaguauac      960

gaauacgccc aaaaacuagg aggagaagca ggauucuacc acauacuaaa uaauccaaaa     1020

gcaucacuac uaagccuaac ccaauuuccc cacuucucaa guguaguauu aggaaaugca     1080

gcuggacuag gaauaauggg agaauacaga ggaacaccaa gaaaccaaga cuuauacgac     1140

gcagcaaaag cauacgcaga gcaacuuaaa gaaaacggag uaauaaacua uagcguacua     1200

gacuuaacag cagaagaacu ggaagcaaua aaacaucaau uaaacccgaa agacaaugac     1260

guagaauuau aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10230
<211>  1484
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10230
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacucucgaa aguaaaacuc      120

aacgacaccc ucaacaaaga ccaacuccuu uccagcucca aauacaccau ccaacgaucc      180

accggagacu ccaucgacac gcccaacuac gacguccaga aacacaucaa caagcucugc      240

ggaaugcuac uaaucaccga ggacgccaac cacaaauuca caggacuuau agggaugcuc      300

uacgccaugu cccgccucgg acgcgaagac acaauaaaaa uccuacgaga cgccggcuac      360

cacguaaagg caaacggcgu cgacgucacc acacacagac aagacaucaa cggaaaggaa      420

augaaauucg aaguccucac ccucgccagc cuaaccaccg agauccaaau caacaucgaa      480

aucgaaucac gcaaauccua caagaaaaug cucaaagaaa ugggagaagu cgcccccgaa      540

uaccgucacg acucgcccga cugcggcaug auaauccuau gcaucgccgc acucgucaua      600

accaaacucg ccgccgguga ccgaucagga cugacagcag ucauccgccg agcaaacaac      660

gugcucaaaa acgaaaugaa acgcuacaaa ggccuacucc ccaaagacau cgccaacucc      720

uucuacgaag ucuucgaaaa acacccacac uucaucgacg ucuucgucca cuucggcauc      780

gcacaaucau caaccagagg cggcagccgc guugaaggca ucuucgcagg acucuuuaug      840

aacgccuacg gcgccggcca agucaugcuc cgcuggggcg uccuggcaaa aagcgucaaa      900

aacaucaugc uaggccacgc uagcguccaa gccgaaaugg aacaagucgu cgaaguuuac      960

gaguacgcac aaaaacucgg cggcgaagca ggcuucuacc acauccuaaa caaccccaaa     1020

gccucccugc uaucacucac ccaauucccc cacuucucca gcgucguccu cggcaacgcc     1080

gcaggacuag gcaucauggg agaauaccgc gggacaccgc gcaaccaaga ccucuacgac     1140

gccgccaaag ccuacgccga acaacucaaa gaaaacggcg ucauaaacua cucaguccuc     1200

gaccucaccg ccgaagaacu cgaagccauc aaacaccaac ucaacccaaa agacaacgac     1260

gucgaauuau aaggacuagu guccaccugu cccuccuggg cugcuggauu gucucguuuu     1320

ccugccaaau aaacaggauc agcgcuuuac agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1440

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1484


<210>  10231
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10231
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcuc uuagcaaagu caaguugaau gauacacuca acaaagauca acuucuguca      180

uccagcaaau acaccaucca acggagcaca ggagauagua uugauacucc uaauuaugau      240

gugcagaaac acaucaauaa guuauguggc auguuauuaa ucacagaaga ugcuaaucau      300

aaauucacug gguuaauagg uauguuauau gcgaugucua gguuaggaag agaagacacc      360

auaaaaauac ucagagaugc gggauaucau guaaaagcaa auggaguaga uguaacaaca      420

caucgucaag acauuaaugg aaaagaaaug aaauuugaag uguuaacauu ggcaagcuua      480

acaacugaaa uucaaaucaa cauugagaua gaaucuagaa aauccuacaa aaaaaugcua      540

aaagaaaugg gagagguagc uccagaauac aggcaugacu cuccugauug ugggaugaua      600

auauuaugua uagcagcauu aguaauaacu aaauuagcag caggggacag aucuggucuu      660

acagccguga uuaggagagc uaauaauguc cuaaaaaaug aaaugaaacg uuacaaaggc      720

uuacuaccca aggacauagc caacagcuuc uaugaagugu uugaaaaaca uccccacuuu      780

auagauguuu uuguucauuu ugguauagca caaucuucua ccagaggugg caguagaguu      840

gaagggauuu uugcaggauu guuuaugaau gccuauggug cagggcaagu gauguuacgg      900

uggggagucu uagcaaaauc aguuaaaaau auuauguuag gacaugcuag ugugcaagca      960

gaaauggaac aaguuguuga gguuuaugaa uaugcccaaa aauugggugg ugaagcagga     1020

uucuaccaua uauugaacaa cccaaaagca ucauuauuau cuuugacuca auuuccucac     1080

uucuccagug uaguauuagg caaugcugcu ggccuaggca uaaugggaga guacagaggu     1140

acaccgagga aucaagaucu auaugaugca gcaaaggcau augcugaaca acucaaagaa     1200

aaugguguga uuaacuacag uguacuagac uugacagcag aagaacuaga ggcuaucaaa     1260

caucagcuua auccaaaaga uaaugaugua gagcuuugag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10232
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10232
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcucaac gacacccuga acaaggacca gcugcucucc      180

agcuccaagu acaccaucca gcgcagcacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcugugcggg augcugcuca ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg gaugcuguac gcgaugagcc ggcucggccg cgaggacacg      360

aucaagaucc ugcgggacgc cggguaccac gugaaggcca acggcgugga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg ugcugacccu cgccucccug      480

acgaccgaga uccagaucaa caucgagauc gagagccgga aguccuacaa gaagaugcug      540

aaggagaugg gggagguggc cccggaguac cgccacgaca gccccgacug cggcaugauc      600

auccucugca ucgcggcccu ggucaucacc aagcuggccg ccggggaccg guccggccuc      660

accgcgguga uccgccgggc caacaacgug cugaagaacg agaugaagcg cuacaagggg      720

cugcucccca aggacaucgc caacagcuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc caguccagca cgcggggcgg gucccgcguc      840

gagggcaucu ucgccgggcu guucaugaac gcguacggcg ccggccaggu gaugcugcgg      900

uggggcgugc ucgccaagag cgucaagaac aucaugcugg ggcacgccuc cgugcaggcc      960

gagauggagc aggucgugga gguguacgag uacgcgcaga agcucggggg cgaggccggg     1020

uucuaccaca uccugaacaa cccgaaggcc agccugcugu cccucaccca guucccccac     1080

uucagcagcg ugguccuggg caacgccgcc ggccugggga ucaugggcga guaccgcggg     1140

acgccccgga accaggaccu cuacgacgcg gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacuc cgugcuggac cucaccgccg aggagcugga ggcgaucaag     1260

caccagcuga accccaagga caacgacguc gagcucugag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10233
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10233
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ucuccaaggu caagcucaac gacacccuca acaaggacca gcuccucucc      180

uccuccaagu acaccaucca gcgcuccacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcucugcggc augcuccuca ucaccgagga cgccaaccac      300

aaguucaccg gccucaucgg caugcucuac gccauguccc gccucggccg cgaggacacc      360

aucaagaucc uccgcgacgc cggcuaccac gucaaggcca acggcgucga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg uccucacccu cgccucccuc      480

accaccgaga uccagaucaa caucgagauc gagucccgca aguccuacaa gaagaugcuc      540

aaggagaugg gcgaggucgc ccccgaguac cgccacgacu cccccgacug cggcaugauc      600

auccucugca ucgccgcccu cgucaucacc aagcucgccg ccggcgaccg cuccggccuc      660

accgccguca uccgccgcgc caacaacguc cucaagaacg agaugaagcg cuacaagggc      720

cuccucccca aggacaucgc caacuccuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgucu ucguccacuu cggcaucgcc caguccucca cccgcggcgg cucccgcguc      840

gagggcaucu ucgccggccu cuucaugaac gccuacggcg ccggccaggu caugcuccgc      900

uggggcgucc ucgccaaguc cgucaagaac aucaugcucg gccacgccuc cguccaggcc      960

gagauggagc aggucgucga ggucuacgag uacgcccaga agcucggcgg cgaggccggc     1020

uucuaccaca uccucaacaa ccccaaggcc ucccuccucu cccucaccca guucccccac     1080

uucuccuccg ucguccucgg caacgccgcc ggccucggca ucaugggcga guaccgcggc     1140

accccccgca accaggaccu cuacgacgcc gccaaggccu acgccgagca gcucaaggag     1200

aacggcguca ucaacuacuc cguccucgac cucaccgccg aggagcucga ggccaucaag     1260

caccagcuca accccaagga caacgacguc gagcucugag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10234
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10234
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuua auaaggauca gcuguugucc      180

ucuucaaaau acacaaucca aagaaguacu ggcgacagca uugauacgcc caacuaugac      240

guccagaagc acauaaauaa auuaugcggg augcugcuaa ucaccgagga ugcuaaccau      300

aaguucacag gacucauugg uaugcuguac gcaaugucca ggcuuggccg ggaagacacu      360

aucaagauuc ugcgcgaugc cggguaucac guuaaagcga auggagugga cguaaccaca      420

caucgacagg auaucaacgg caaggagaug aaauuugaag uguugacccu cgcuucucug      480

acuacagaga uacagaucaa uauugaaauc gagucgcgua agucauacaa aaagaugcug      540

aaggagaugg gugaagucgc cccugaguau agacacgaca gcccagauug ugggaugauu      600

auccucugca uagcagccuu agugauuacc aaacuggcug caggagacag gaguggccuu      660

acggccguua uccggcgcgc uaacaaugug uugaagaacg aaaugaaaag auacaagggc      720

cugcuaccga aagauauugc caauuccuuc uaugaggucu uugagaagca uccccacuuc      780

aucgacgugu uuguacacuu cgggaucgcg caaucuagca cuaggggagg uucccggguu      840

gaaggcauuu uugcaggacu cuucaugaac gccuacgggg cuggccaggu gaugcugcgc      900

uggggugucc uugccaaauc agugaagaau auaaugcugg ggcaugcaag ugugcaggcu      960

gagauggaac aggucguuga gguguacgaa uaugcccaaa aguugggagg cgaggcgggc     1020

uuuuaccaca uccucaacaa uccuaaagcc agccuguuau cucugaccca guucccacau     1080

uuuuccucag uagugcucgg gaacgcagcu ggacuuggua uuaugggcga guaucgaggg     1140

acacccagaa accaggaccu guacgaugcc gcuaaggccu augcagaaca guugaaagag     1200

aauggaguca ucaacuacag cgugcuagac cugacugccg aggaacucga agcuauaaag     1260

caccaacuga auccuaaaga uaacgacguu gagcuuugag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10235
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10235
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcugaac gacacccuga acaaggacca gcugcugagc      180

agcagcaagu acaccaucca gagaagcacc ggcgacagca ucgacacccc caacuacgac      240

gugcagaagc acaucaacaa gcugugcggc augcugcuga ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg caugcuguac gccaugagca gacugggcag agaggacacc      360

aucaagaucc ugagagacgc cggcuaccac gugaaggcca acggcgugga cgugaccacc      420

cacagacagg acaucaacgg caaggagaug aaguucgagg ugcugacccu ggccagccug      480

accaccgaga uccagaucaa caucgagauc gagagcagaa agagcuacaa gaagaugcug      540

aaggagaugg gcgagguggc ccccgaguac agacacgaca gccccgacug cggcaugauc      600

auccugugca ucgccgcccu ggugaucacc aagcuggccg ccggcgacag aagcggccug      660

accgccguga ucagaagagc caacaacgug cugaagaacg agaugaagag auacaagggc      720

cugcugccca aggacaucgc caacagcuuc uacgaggugu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc cagagcagca ccagaggcgg cagcagagug      840

gagggcaucu ucgccggccu guucaugaac gccuacggcg ccggccaggu gaugcugaga      900

uggggcgugc uggccaagag cgugaagaac aucaugcugg gccacgccag cgugcaggcc      960

gagauggagc agguggugga gguguacgag uacgcccaga agcugggcgg cgaggccggc     1020

uucuaccaca uccugaacaa ccccaaggcc agccugcuga gccugaccca guucccccac     1080

uucagcagcg uggugcuggg caacgccgcc ggccugggca ucaugggcga guacagaggc     1140

acccccagaa accaggaccu guacgacgcc gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacag cgugcuggac cugaccgccg aggagcugga ggccaucaag     1260

caccagcuga accccaagga caacgacgug gagcugugag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10236
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10236
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuga auaaggauca gcuucugucc      180

ucuagcaaau acacaaucca aagauccacg ggcgacucua uugauacccc caacuaugac      240

guccagaagc acaucaauaa acucugcggg augcugcuua uuacagagga ugcuaaccau      300

aaguucaccg gacugaucgg caugcucuac gccaugagcc ggcuggggcg cgaagacaca      360

auuaagaucc ugagagaugc gggauaucac guuaaagcua auggcgugga cgugaccaca      420

caucggcagg auaucaacgg gaaggagaug aaauuugaag uccucacccu ggccucccuu      480

acgaccgaga uucagaucaa uauugaaauc gagucucgca agagcuacaa aaagaugcug      540

aaggagaugg gagaaguggc cccugaguau agacacgacu ccccggauug uggcaugauu      600

auccucugca uugcugcccu gguuaucaca aaacuugcug ccggcgaccg gagcgggcug      660

accgcgguga uccgcagagc caacaauguc cucaagaacg aaaugaaacg guacaaggga      720

cugcugccca aagauauugc uaauucuuuc uaugaggugu uugagaagca uccucacuuc      780

aucgacguuu uugugcacuu cggcauugcc caauccagca cacgcggggg aucuagaguc      840

gaaggcaucu uugcuggacu cuucaugaac gccuacgggg cgggccaggu gaugcugcgg      900

uggggcgugc uugccaaauc cgucaagaau auuaugcugg ggcaugcuag cguucaggcc      960

gagauggaac agguggugga ggucuacgaa uaugcucaaa agcucggagg cgaggccggg     1020

uuuuaccaca uccugaacaa ucccaaagcc ucucuucugu cccucaccca guucccucau     1080

uuuagcuccg ugguucuggg aaacgcugcg ggccugggga ucaugggaga guaucgcggc     1140

acgcccagaa accaggaccu cuacgaugcc gcuaaggccu augccgaaca gcugaaagag     1200

aauggcguga uuaacuacuc uguccuugac cugacagcug aggaacucga agccaucaag     1260

caccaacuga auccuaaaga uaacgacgug gagcuuugag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10237
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10237
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac uaagcaaagu caaauuaaac gacacauuaa acaaagacca acucuuauca      180

ucaucaaaau acacaauaca aagaagcacc ggagacagua ucgacacacc aaacuaugac      240

guccaaaaac auauaaauaa auuaugcggc augcucuuaa ucacagaaga cgccaaccau      300

aaauuuacag gauuaauagg aauguuauau gcaaugucac gacuagguag agaagacaca      360

auaaaaauac uaagagacgc aggcuaucac guaaaagcaa auggaguaga cguaaccaca      420

cacagacaag acauaaaugg aaaagaaaug aaauuugaag uauuaacacu agcaucacua      480

acaacagaaa uacaaaucaa cauagaaaua gaaucaagaa aaagcuacaa aaaaauguua      540

aaagaaaugg gagaagucgc accagaauau agacaugauu caccagacug cggaaugaua      600

auacuaugca uagcagcccu aguaauuaca aaacuagcag caggagacag aagcggauua      660

acagcaguaa uaagaagagc aaacaacgua cuaaaaaacg aaaugaaaag auauaaagga      720

uuauuaccaa aagacauagc aaacucauuc uaugaaguau ucgaaaaaca cccccacuuu      780

auagacgucu ucguacacuu cggaauagcc caaucaucca caagaggagg aucaagaguc      840

gaaggaauau ucgcaggauu auucaugaac gcauauggcg caggacaagu aaugcuaaga      900

uggggaguac uagcaaaauc cgucaaaaac auaaugcuag gacacgcauc aguucaagca      960

gaaauggaac aaguaguaga aguauacgaa uacgcccaaa aacuaggagg agaagcagga     1020

uucuaccaca uacuaaauaa uccaaaagca ucacuacuaa gccuaaccca auuuccccac     1080

uucucaagug uaguauuagg aaaugcagcu ggacuaggaa uaaugggaga auacagagga     1140

acaccaagaa accaagacuu auacgacgca gcaaaagcau acgcagagca acuuaaagaa     1200

aacggaguaa uaaacuauag cguacuagac uuaacagcag aagaacugga agcaauaaaa     1260

caucaauuaa acccgaaaga caaugacgua gaauuauaag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10238
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10238
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac ucucgaaagu aaaacucaac gacacccuca acaaagacca acuccuuucc      180

agcuccaaau acaccaucca acgauccacc ggagacucca ucgacacgcc caacuacgac      240

guccagaaac acaucaacaa gcucugcgga augcuacuaa ucaccgagga cgccaaccac      300

aaauucacag gacuuauagg gaugcucuac gccauguccc gccucggacg cgaagacaca      360

auaaaaaucc uacgagacgc cggcuaccac guaaaggcaa acggcgucga cgucaccaca      420

cacagacaag acaucaacgg aaaggaaaug aaauucgaag uccucacccu cgccagccua      480

accaccgaga uccaaaucaa caucgaaauc gaaucacgca aauccuacaa gaaaaugcuc      540

aaagaaaugg gagaagucgc ccccgaauac cgucacgacu cgcccgacug cggcaugaua      600

auccuaugca ucgccgcacu cgucauaacc aaacucgccg ccggugaccg aucaggacug      660

acagcaguca uccgccgagc aaacaacgug cucaaaaacg aaaugaaacg cuacaaaggc      720

cuacucccca aagacaucgc caacuccuuc uacgaagucu ucgaaaaaca cccacacuuc      780

aucgacgucu ucguccacuu cggcaucgca caaucaucaa ccagaggcgg cagccgcguu      840

gaaggcaucu ucgcaggacu cuuuaugaac gccuacggcg ccggccaagu caugcuccgc      900

uggggcgucc uggcaaaaag cgucaaaaac aucaugcuag gccacgcuag cguccaagcc      960

gaaauggaac aagucgucga aguuuacgag uacgcacaaa aacucggcgg cgaagcaggc     1020

uucuaccaca uccuaaacaa ccccaaagcc ucccugcuau cacucaccca auucccccac     1080

uucuccagcg ucguccucgg caacgccgca ggacuaggca ucaugggaga auaccgcggg     1140

acaccgcgca accaagaccu cuacgacgcc gccaaagccu acgccgaaca acucaaagaa     1200

aacggcguca uaaacuacuc aguccucgac cucaccgccg aagaacucga agccaucaaa     1260

caccaacuca acccaaaaga caacgacguc gaauuauaag gacuagugga agcauuuucc     1320

uggcugauua aaagaaauua cucagcuaug gucaucuguu ccuguuagaa ggcuaugcag     1380

cauauuauau acuaugcgca uguuaugaaa ugcauaauaa aaaauuuuaa aaaaucuaaa     1440

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1560

gagccaccag aauu                                                       1574


<210>  10239
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10239
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cucuuagcaa agucaaguug      120

aaugauacac ucaacaaaga ucaacuucug ucauccagca aauacaccau ccaacggagc      180

acaggagaua guauugauac uccuaauuau gaugugcaga aacacaucaa uaaguuaugu      240

ggcauguuau uaaucacaga agaugcuaau cauaaauuca cuggguuaau agguauguua      300

uaugcgaugu cuagguuagg aagagaagac accauaaaaa uacucagaga ugcgggauau      360

cauguaaaag caaauggagu agauguaaca acacaucguc aagacauuaa uggaaaagaa      420

augaaauuug aaguguuaac auuggcaagc uuaacaacug aaauucaaau caacauugag      480

auagaaucua gaaaauccua caaaaaaaug cuaaaagaaa ugggagaggu agcuccagaa      540

uacaggcaug acucuccuga uugugggaug auaauauuau guauagcagc auuaguaaua      600

acuaaauuag cagcagggga cagaucuggu cuuacagccg ugauuaggag agcuaauaau      660

guccuaaaaa augaaaugaa acguuacaaa ggcuuacuac ccaaggacau agccaacagc      720

uucuaugaag uguuugaaaa acauccccac uuuauagaug uuuuuguuca uuuugguaua      780

gcacaaucuu cuaccagagg uggcaguaga guugaaggga uuuuugcagg auuguuuaug      840

aaugccuaug gugcagggca agugauguua cgguggggag ucuuagcaaa aucaguuaaa      900

aauauuaugu uaggacaugc uagugugcaa gcagaaaugg aacaaguugu ugagguuuau      960

gaauaugccc aaaaauuggg uggugaagca ggauucuacc auauauugaa caacccaaaa     1020

gcaucauuau uaucuuugac ucaauuuccu cacuucucca guguaguauu aggcaaugcu     1080

gcuggccuag gcauaauggg agaguacaga gguacaccga ggaaucaaga ucuauaugau     1140

gcagcaaagg cauaugcuga acaacucaaa gaaaauggug ugauuaacua caguguacua     1200

gacuugacag cagaagaacu agaggcuauc aaacaucagc uuaauccaaa agauaaugau     1260

guagagcuuu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10240
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10240
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcuc      120

aacgacaccc ugaacaagga ccagcugcuc uccagcucca aguacaccau ccagcgcagc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcugugc      240

gggaugcugc ucaucaccga ggacgccaac cacaaguuca ccggccugau cgggaugcug      300

uacgcgauga gccggcucgg ccgcgaggac acgaucaaga uccugcggga cgccggguac      360

cacgugaagg ccaacggcgu ggacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccucgccucc cugacgaccg agauccagau caacaucgag      480

aucgagagcc ggaaguccua caagaagaug cugaaggaga ugggggaggu ggccccggag      540

uaccgccacg acagccccga cugcggcaug aucauccucu gcaucgcggc ccuggucauc      600

accaagcugg ccgccgggga ccgguccggc cucaccgcgg ugauccgccg ggccaacaac      660

gugcugaaga acgagaugaa gcgcuacaag gggcugcucc ccaaggacau cgccaacagc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagucca gcacgcgggg cgggucccgc gucgagggca ucuucgccgg gcuguucaug      840

aacgcguacg gcgccggcca ggugaugcug cgguggggcg ugcucgccaa gagcgucaag      900

aacaucaugc uggggcacgc cuccgugcag gccgagaugg agcaggucgu ggagguguac      960

gaguacgcgc agaagcucgg gggcgaggcc ggguucuacc acauccugaa caacccgaag     1020

gccagccugc ugucccucac ccaguucccc cacuucagca gcgugguccu gggcaacgcc     1080

gccggccugg ggaucauggg cgaguaccgc gggacgcccc ggaaccagga ccucuacgac     1140

gcggccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cuccgugcug     1200

gaccucaccg ccgaggagcu ggaggcgauc aagcaccagc ugaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10241
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10241
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccucuccaa ggucaagcuc      120

aacgacaccc ucaacaagga ccagcuccuc uccuccucca aguacaccau ccagcgcucc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcucugc      240

ggcaugcucc ucaucaccga ggacgccaac cacaaguuca ccggccucau cggcaugcuc      300

uacgccaugu cccgccucgg ccgcgaggac accaucaaga uccuccgcga cgccggcuac      360

cacgucaagg ccaacggcgu cgacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg agguccucac ccucgccucc cucaccaccg agauccagau caacaucgag      480

aucgaguccc gcaaguccua caagaagaug cucaaggaga ugggcgaggu cgcccccgag      540

uaccgccacg acucccccga cugcggcaug aucauccucu gcaucgccgc ccucgucauc      600

accaagcucg ccgccggcga ccgcuccggc cucaccgccg ucauccgccg cgccaacaac      660

guccucaaga acgagaugaa gcgcuacaag ggccuccucc ccaaggacau cgccaacucc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg ucuucgucca cuucggcauc      780

gcccaguccu ccacccgcgg cggcucccgc gucgagggca ucuucgccgg ccucuucaug      840

aacgccuacg gcgccggcca ggucaugcuc cgcuggggcg uccucgccaa guccgucaag      900

aacaucaugc ucggccacgc cuccguccag gccgagaugg agcaggucgu cgaggucuac      960

gaguacgccc agaagcucgg cggcgaggcc ggcuucuacc acauccucaa caaccccaag     1020

gccucccucc ucucccucac ccaguucccc cacuucuccu ccgucguccu cggcaacgcc     1080

gccggccucg gcaucauggg cgaguaccgc ggcacccccc gcaaccagga ccucuacgac     1140

gccgccaagg ccuacgccga gcagcucaag gagaacggcg ucaucaacua cuccguccuc     1200

gaccucaccg ccgaggagcu cgaggccauc aagcaccagc ucaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10242
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10242
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc uuaauaagga ucagcuguug uccucuucaa aauacacaau ccaaagaagu      180

acuggcgaca gcauugauac gcccaacuau gacguccaga agcacauaaa uaaauuaugc      240

gggaugcugc uaaucaccga ggaugcuaac cauaaguuca caggacucau ugguaugcug      300

uacgcaaugu ccaggcuugg ccgggaagac acuaucaaga uucugcgcga ugccggguau      360

cacguuaaag cgaauggagu ggacguaacc acacaucgac aggauaucaa cggcaaggag      420

augaaauuug aaguguugac ccucgcuucu cugacuacag agauacagau caauauugaa      480

aucgagucgc guaagucaua caaaaagaug cugaaggaga ugggugaagu cgccccugag      540

uauagacacg acagcccaga uugugggaug auuauccucu gcauagcagc cuuagugauu      600

accaaacugg cugcaggaga caggaguggc cuuacggccg uuauccggcg cgcuaacaau      660

guguugaaga acgaaaugaa aagauacaag ggccugcuac cgaaagauau ugccaauucc      720

uucuaugagg ucuuugagaa gcauccccac uucaucgacg uguuuguaca cuucgggauc      780

gcgcaaucua gcacuagggg agguucccgg guugaaggca uuuuugcagg acucuucaug      840

aacgccuacg gggcuggcca ggugaugcug cgcuggggug uccuugccaa aucagugaag      900

aauauaaugc uggggcaugc aagugugcag gcugagaugg aacaggucgu ugagguguac      960

gaauaugccc aaaaguuggg aggcgaggcg ggcuuuuacc acauccucaa caauccuaaa     1020

gccagccugu uaucucugac ccaguuccca cauuuuuccu caguagugcu cgggaacgca     1080

gcuggacuug guauuauggg cgaguaucga gggacaccca gaaaccagga ccuguacgau     1140

gccgcuaagg ccuaugcaga acaguugaaa gagaauggag ucaucaacua cagcgugcua     1200

gaccugacug ccgaggaacu cgaagcuaua aagcaccaac ugaauccuaa agauaacgac     1260

guugagcuuu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10243
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10243
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcug      120

aacgacaccc ugaacaagga ccagcugcug agcagcagca aguacaccau ccagagaagc      180

accggcgaca gcaucgacac ccccaacuac gacgugcaga agcacaucaa caagcugugc      240

ggcaugcugc ugaucaccga ggacgccaac cacaaguuca ccggccugau cggcaugcug      300

uacgccauga gcagacuggg cagagaggac accaucaaga uccugagaga cgccggcuac      360

cacgugaagg ccaacggcgu ggacgugacc acccacagac aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccuggccagc cugaccaccg agauccagau caacaucgag      480

aucgagagca gaaagagcua caagaagaug cugaaggaga ugggcgaggu ggcccccgag      540

uacagacacg acagccccga cugcggcaug aucauccugu gcaucgccgc ccuggugauc      600

accaagcugg ccgccggcga cagaagcggc cugaccgccg ugaucagaag agccaacaac      660

gugcugaaga acgagaugaa gagauacaag ggccugcugc ccaaggacau cgccaacagc      720

uucuacgagg uguucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagagca gcaccagagg cggcagcaga guggagggca ucuucgccgg ccuguucaug      840

aacgccuacg gcgccggcca ggugaugcug agauggggcg ugcuggccaa gagcgugaag      900

aacaucaugc ugggccacgc cagcgugcag gccgagaugg agcagguggu ggagguguac      960

gaguacgccc agaagcuggg cggcgaggcc ggcuucuacc acauccugaa caaccccaag     1020

gccagccugc ugagccugac ccaguucccc cacuucagca gcguggugcu gggcaacgcc     1080

gccggccugg gcaucauggg cgaguacaga ggcaccccca gaaaccagga ccuguacgac     1140

gccgccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cagcgugcug     1200

gaccugaccg ccgaggagcu ggaggccauc aagcaccagc ugaaccccaa ggacaacgac     1260

guggagcugu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10244
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10244
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc ugaauaagga ucagcuucug uccucuagca aauacacaau ccaaagaucc      180

acgggcgacu cuauugauac ccccaacuau gacguccaga agcacaucaa uaaacucugc      240

gggaugcugc uuauuacaga ggaugcuaac cauaaguuca ccggacugau cggcaugcuc      300

uacgccauga gccggcuggg gcgcgaagac acaauuaaga uccugagaga ugcgggauau      360

cacguuaaag cuaauggcgu ggacgugacc acacaucggc aggauaucaa cgggaaggag      420

augaaauuug aaguccucac ccuggccucc cuuacgaccg agauucagau caauauugaa      480

aucgagucuc gcaagagcua caaaaagaug cugaaggaga ugggagaagu ggccccugag      540

uauagacacg acuccccgga uuguggcaug auuauccucu gcauugcugc ccugguuauc      600

acaaaacuug cugccggcga ccggagcggg cugaccgcgg ugauccgcag agccaacaau      660

guccucaaga acgaaaugaa acgguacaag ggacugcugc ccaaagauau ugcuaauucu      720

uucuaugagg uguuugagaa gcauccucac uucaucgacg uuuuugugca cuucggcauu      780

gcccaaucca gcacacgcgg gggaucuaga gucgaaggca ucuuugcugg acucuucaug      840

aacgccuacg gggcgggcca ggugaugcug cgguggggcg ugcuugccaa auccgucaag      900

aauauuaugc uggggcaugc uagcguucag gccgagaugg aacagguggu ggaggucuac      960

gaauaugcuc aaaagcucgg aggcgaggcc ggguuuuacc acauccugaa caaucccaaa     1020

gccucucuuc ugucccucac ccaguucccu cauuuuagcu ccgugguucu gggaaacgcu     1080

gcgggccugg ggaucauggg agaguaucgc ggcacgccca gaaaccagga ccucuacgau     1140

gccgcuaagg ccuaugccga acagcugaaa gagaauggcg ugauuaacua cucuguccuu     1200

gaccugacag cugaggaacu cgaagccauc aagcaccaac ugaauccuaa agauaacgac     1260

guggagcuuu gaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10245
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10245
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacuaagcaa agucaaauua      120

aacgacacau uaaacaaaga ccaacucuua ucaucaucaa aauacacaau acaaagaagc      180

accggagaca guaucgacac accaaacuau gacguccaaa aacauauaaa uaaauuaugc      240

ggcaugcucu uaaucacaga agacgccaac cauaaauuua caggauuaau aggaauguua      300

uaugcaaugu cacgacuagg uagagaagac acaauaaaaa uacuaagaga cgcaggcuau      360

cacguaaaag caaauggagu agacguaacc acacacagac aagacauaaa uggaaaagaa      420

augaaauuug aaguauuaac acuagcauca cuaacaacag aaauacaaau caacauagaa      480

auagaaucaa gaaaaagcua caaaaaaaug uuaaaagaaa ugggagaagu cgcaccagaa      540

uauagacaug auucaccaga cugcggaaug auaauacuau gcauagcagc ccuaguaauu      600

acaaaacuag cagcaggaga cagaagcgga uuaacagcag uaauaagaag agcaaacaac      660

guacuaaaaa acgaaaugaa aagauauaaa ggauuauuac caaaagacau agcaaacuca      720

uucuaugaag uauucgaaaa acacccccac uuuauagacg ucuucguaca cuucggaaua      780

gcccaaucau ccacaagagg aggaucaaga gucgaaggaa uauucgcagg auuauucaug      840

aacgcauaug gcgcaggaca aguaaugcua agauggggag uacuagcaaa auccgucaaa      900

aacauaaugc uaggacacgc aucaguucaa gcagaaaugg aacaaguagu agaaguauac      960

gaauacgccc aaaaacuagg aggagaagca ggauucuacc acauacuaaa uaauccaaaa     1020

gcaucacuac uaagccuaac ccaauuuccc cacuucucaa guguaguauu aggaaaugca     1080

gcuggacuag gaauaauggg agaauacaga ggaacaccaa gaaaccaaga cuuauacgac     1140

gcagcaaaag cauacgcaga gcaacuuaaa gaaaacggag uaauaaacua uagcguacua     1200

gacuuaacag cagaagaacu ggaagcaaua aaacaucaau uaaacccgaa agacaaugac     1260

guagaauuau aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10246
<211>  1551
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10246
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacucucgaa aguaaaacuc      120

aacgacaccc ucaacaaaga ccaacuccuu uccagcucca aauacaccau ccaacgaucc      180

accggagacu ccaucgacac gcccaacuac gacguccaga aacacaucaa caagcucugc      240

ggaaugcuac uaaucaccga ggacgccaac cacaaauuca caggacuuau agggaugcuc      300

uacgccaugu cccgccucgg acgcgaagac acaauaaaaa uccuacgaga cgccggcuac      360

cacguaaagg caaacggcgu cgacgucacc acacacagac aagacaucaa cggaaaggaa      420

augaaauucg aaguccucac ccucgccagc cuaaccaccg agauccaaau caacaucgaa      480

aucgaaucac gcaaauccua caagaaaaug cucaaagaaa ugggagaagu cgcccccgaa      540

uaccgucacg acucgcccga cugcggcaug auaauccuau gcaucgccgc acucgucaua      600

accaaacucg ccgccgguga ccgaucagga cugacagcag ucauccgccg agcaaacaac      660

gugcucaaaa acgaaaugaa acgcuacaaa ggccuacucc ccaaagacau cgccaacucc      720

uucuacgaag ucuucgaaaa acacccacac uucaucgacg ucuucgucca cuucggcauc      780

gcacaaucau caaccagagg cggcagccgc guugaaggca ucuucgcagg acucuuuaug      840

aacgccuacg gcgccggcca agucaugcuc cgcuggggcg uccuggcaaa aagcgucaaa      900

aacaucaugc uaggccacgc uagcguccaa gccgaaaugg aacaagucgu cgaaguuuac      960

gaguacgcac aaaaacucgg cggcgaagca ggcuucuacc acauccuaaa caaccccaaa     1020

gccucccugc uaucacucac ccaauucccc cacuucucca gcgucguccu cggcaacgcc     1080

gcaggacuag gcaucauggg agaauaccgc gggacaccgc gcaaccaaga ccucuacgac     1140

gccgccaaag ccuacgccga acaacucaaa gaaaacggcg ucauaaacua cucaguccuc     1200

gaccucaccg ccgaagaacu cgaagccauc aaacaccaac ucaacccaaa agacaacgac     1260

gucgaauuau aaggacuagu acuggcugca ucucccuuuc cucuguccuc cauccuucuc     1320

ccaggauggu gaagggggac cugguaccca gugaucccca ccccaggauc cuaaaucaug     1380

acuuaccugc uaauaaaaac ucauuggaaa agugagaaga ucuaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1500

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1551


<210>  10247
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10247
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cucuuagcaa agucaaguug      120

aaugauacac ucaacaaaga ucaacuucug ucauccagca aauacaccau ccaacggagc      180

acaggagaua guauugauac uccuaauuau gaugugcaga aacacaucaa uaaguuaugu      240

ggcauguuau uaaucacaga agaugcuaau cauaaauuca cuggguuaau agguauguua      300

uaugcgaugu cuagguuagg aagagaagac accauaaaaa uacucagaga ugcgggauau      360

cauguaaaag caaauggagu agauguaaca acacaucguc aagacauuaa uggaaaagaa      420

augaaauuug aaguguuaac auuggcaagc uuaacaacug aaauucaaau caacauugag      480

auagaaucua gaaaauccua caaaaaaaug cuaaaagaaa ugggagaggu agcuccagaa      540

uacaggcaug acucuccuga uugugggaug auaauauuau guauagcagc auuaguaaua      600

acuaaauuag cagcagggga cagaucuggu cuuacagccg ugauuaggag agcuaauaau      660

guccuaaaaa augaaaugaa acguuacaaa ggcuuacuac ccaaggacau agccaacagc      720

uucuaugaag uguuugaaaa acauccccac uuuauagaug uuuuuguuca uuuugguaua      780

gcacaaucuu cuaccagagg uggcaguaga guugaaggga uuuuugcagg auuguuuaug      840

aaugccuaug gugcagggca agugauguua cgguggggag ucuuagcaaa aucaguuaaa      900

aauauuaugu uaggacaugc uagugugcaa gcagaaaugg aacaaguugu ugagguuuau      960

gaauaugccc aaaaauuggg uggugaagca ggauucuacc auauauugaa caacccaaaa     1020

gcaucauuau uaucuuugac ucaauuuccu cacuucucca guguaguauu aggcaaugcu     1080

gcuggccuag gcauaauggg agaguacaga gguacaccga ggaaucaaga ucuauaugau     1140

gcagcaaagg cauaugcuga acaacucaaa gaaaauggug ugauuaacua caguguacua     1200

gacuugacag cagaagaacu agaggcuauc aaacaucagc uuaauccaaa agauaaugau     1260

guagagcuuu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10248
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10248
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcuc      120

aacgacaccc ugaacaagga ccagcugcuc uccagcucca aguacaccau ccagcgcagc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcugugc      240

gggaugcugc ucaucaccga ggacgccaac cacaaguuca ccggccugau cgggaugcug      300

uacgcgauga gccggcucgg ccgcgaggac acgaucaaga uccugcggga cgccggguac      360

cacgugaagg ccaacggcgu ggacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccucgccucc cugacgaccg agauccagau caacaucgag      480

aucgagagcc ggaaguccua caagaagaug cugaaggaga ugggggaggu ggccccggag      540

uaccgccacg acagccccga cugcggcaug aucauccucu gcaucgcggc ccuggucauc      600

accaagcugg ccgccgggga ccgguccggc cucaccgcgg ugauccgccg ggccaacaac      660

gugcugaaga acgagaugaa gcgcuacaag gggcugcucc ccaaggacau cgccaacagc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagucca gcacgcgggg cgggucccgc gucgagggca ucuucgccgg gcuguucaug      840

aacgcguacg gcgccggcca ggugaugcug cgguggggcg ugcucgccaa gagcgucaag      900

aacaucaugc uggggcacgc cuccgugcag gccgagaugg agcaggucgu ggagguguac      960

gaguacgcgc agaagcucgg gggcgaggcc ggguucuacc acauccugaa caacccgaag     1020

gccagccugc ugucccucac ccaguucccc cacuucagca gcgugguccu gggcaacgcc     1080

gccggccugg ggaucauggg cgaguaccgc gggacgcccc ggaaccagga ccucuacgac     1140

gcggccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cuccgugcug     1200

gaccucaccg ccgaggagcu ggaggcgauc aagcaccagc ugaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10249
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10249
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccucuccaa ggucaagcuc      120

aacgacaccc ucaacaagga ccagcuccuc uccuccucca aguacaccau ccagcgcucc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcucugc      240

ggcaugcucc ucaucaccga ggacgccaac cacaaguuca ccggccucau cggcaugcuc      300

uacgccaugu cccgccucgg ccgcgaggac accaucaaga uccuccgcga cgccggcuac      360

cacgucaagg ccaacggcgu cgacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg agguccucac ccucgccucc cucaccaccg agauccagau caacaucgag      480

aucgaguccc gcaaguccua caagaagaug cucaaggaga ugggcgaggu cgcccccgag      540

uaccgccacg acucccccga cugcggcaug aucauccucu gcaucgccgc ccucgucauc      600

accaagcucg ccgccggcga ccgcuccggc cucaccgccg ucauccgccg cgccaacaac      660

guccucaaga acgagaugaa gcgcuacaag ggccuccucc ccaaggacau cgccaacucc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg ucuucgucca cuucggcauc      780

gcccaguccu ccacccgcgg cggcucccgc gucgagggca ucuucgccgg ccucuucaug      840

aacgccuacg gcgccggcca ggucaugcuc cgcuggggcg uccucgccaa guccgucaag      900

aacaucaugc ucggccacgc cuccguccag gccgagaugg agcaggucgu cgaggucuac      960

gaguacgccc agaagcucgg cggcgaggcc ggcuucuacc acauccucaa caaccccaag     1020

gccucccucc ucucccucac ccaguucccc cacuucuccu ccgucguccu cggcaacgcc     1080

gccggccucg gcaucauggg cgaguaccgc ggcacccccc gcaaccagga ccucuacgac     1140

gccgccaagg ccuacgccga gcagcucaag gagaacggcg ucaucaacua cuccguccuc     1200

gaccucaccg ccgaggagcu cgaggccauc aagcaccagc ucaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10250
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10250
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc uuaauaagga ucagcuguug uccucuucaa aauacacaau ccaaagaagu      180

acuggcgaca gcauugauac gcccaacuau gacguccaga agcacauaaa uaaauuaugc      240

gggaugcugc uaaucaccga ggaugcuaac cauaaguuca caggacucau ugguaugcug      300

uacgcaaugu ccaggcuugg ccgggaagac acuaucaaga uucugcgcga ugccggguau      360

cacguuaaag cgaauggagu ggacguaacc acacaucgac aggauaucaa cggcaaggag      420

augaaauuug aaguguugac ccucgcuucu cugacuacag agauacagau caauauugaa      480

aucgagucgc guaagucaua caaaaagaug cugaaggaga ugggugaagu cgccccugag      540

uauagacacg acagcccaga uugugggaug auuauccucu gcauagcagc cuuagugauu      600

accaaacugg cugcaggaga caggaguggc cuuacggccg uuauccggcg cgcuaacaau      660

guguugaaga acgaaaugaa aagauacaag ggccugcuac cgaaagauau ugccaauucc      720

uucuaugagg ucuuugagaa gcauccccac uucaucgacg uguuuguaca cuucgggauc      780

gcgcaaucua gcacuagggg agguucccgg guugaaggca uuuuugcagg acucuucaug      840

aacgccuacg gggcuggcca ggugaugcug cgcuggggug uccuugccaa aucagugaag      900

aauauaaugc uggggcaugc aagugugcag gcugagaugg aacaggucgu ugagguguac      960

gaauaugccc aaaaguuggg aggcgaggcg ggcuuuuacc acauccucaa caauccuaaa     1020

gccagccugu uaucucugac ccaguuccca cauuuuuccu caguagugcu cgggaacgca     1080

gcuggacuug guauuauggg cgaguaucga gggacaccca gaaaccagga ccuguacgau     1140

gccgcuaagg ccuaugcaga acaguugaaa gagaauggag ucaucaacua cagcgugcua     1200

gaccugacug ccgaggaacu cgaagcuaua aagcaccaac ugaauccuaa agauaacgac     1260

guugagcuuu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10251
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10251
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcug      120

aacgacaccc ugaacaagga ccagcugcug agcagcagca aguacaccau ccagagaagc      180

accggcgaca gcaucgacac ccccaacuac gacgugcaga agcacaucaa caagcugugc      240

ggcaugcugc ugaucaccga ggacgccaac cacaaguuca ccggccugau cggcaugcug      300

uacgccauga gcagacuggg cagagaggac accaucaaga uccugagaga cgccggcuac      360

cacgugaagg ccaacggcgu ggacgugacc acccacagac aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccuggccagc cugaccaccg agauccagau caacaucgag      480

aucgagagca gaaagagcua caagaagaug cugaaggaga ugggcgaggu ggcccccgag      540

uacagacacg acagccccga cugcggcaug aucauccugu gcaucgccgc ccuggugauc      600

accaagcugg ccgccggcga cagaagcggc cugaccgccg ugaucagaag agccaacaac      660

gugcugaaga acgagaugaa gagauacaag ggccugcugc ccaaggacau cgccaacagc      720

uucuacgagg uguucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagagca gcaccagagg cggcagcaga guggagggca ucuucgccgg ccuguucaug      840

aacgccuacg gcgccggcca ggugaugcug agauggggcg ugcuggccaa gagcgugaag      900

aacaucaugc ugggccacgc cagcgugcag gccgagaugg agcagguggu ggagguguac      960

gaguacgccc agaagcuggg cggcgaggcc ggcuucuacc acauccugaa caaccccaag     1020

gccagccugc ugagccugac ccaguucccc cacuucagca gcguggugcu gggcaacgcc     1080

gccggccugg gcaucauggg cgaguacaga ggcaccccca gaaaccagga ccuguacgac     1140

gccgccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cagcgugcug     1200

gaccugaccg ccgaggagcu ggaggccauc aagcaccagc ugaaccccaa ggacaacgac     1260

guggagcugu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10252
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10252
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc ugaauaagga ucagcuucug uccucuagca aauacacaau ccaaagaucc      180

acgggcgacu cuauugauac ccccaacuau gacguccaga agcacaucaa uaaacucugc      240

gggaugcugc uuauuacaga ggaugcuaac cauaaguuca ccggacugau cggcaugcuc      300

uacgccauga gccggcuggg gcgcgaagac acaauuaaga uccugagaga ugcgggauau      360

cacguuaaag cuaauggcgu ggacgugacc acacaucggc aggauaucaa cgggaaggag      420

augaaauuug aaguccucac ccuggccucc cuuacgaccg agauucagau caauauugaa      480

aucgagucuc gcaagagcua caaaaagaug cugaaggaga ugggagaagu ggccccugag      540

uauagacacg acuccccgga uuguggcaug auuauccucu gcauugcugc ccugguuauc      600

acaaaacuug cugccggcga ccggagcggg cugaccgcgg ugauccgcag agccaacaau      660

guccucaaga acgaaaugaa acgguacaag ggacugcugc ccaaagauau ugcuaauucu      720

uucuaugagg uguuugagaa gcauccucac uucaucgacg uuuuugugca cuucggcauu      780

gcccaaucca gcacacgcgg gggaucuaga gucgaaggca ucuuugcugg acucuucaug      840

aacgccuacg gggcgggcca ggugaugcug cgguggggcg ugcuugccaa auccgucaag      900

aauauuaugc uggggcaugc uagcguucag gccgagaugg aacagguggu ggaggucuac      960

gaauaugcuc aaaagcucgg aggcgaggcc ggguuuuacc acauccugaa caaucccaaa     1020

gccucucuuc ugucccucac ccaguucccu cauuuuagcu ccgugguucu gggaaacgcu     1080

gcgggccugg ggaucauggg agaguaucgc ggcacgccca gaaaccagga ccucuacgau     1140

gccgcuaagg ccuaugccga acagcugaaa gagaauggcg ugauuaacua cucuguccuu     1200

gaccugacag cugaggaacu cgaagccauc aagcaccaac ugaauccuaa agauaacgac     1260

guggagcuuu gaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10253
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10253
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacuaagcaa agucaaauua      120

aacgacacau uaaacaaaga ccaacucuua ucaucaucaa aauacacaau acaaagaagc      180

accggagaca guaucgacac accaaacuau gacguccaaa aacauauaaa uaaauuaugc      240

ggcaugcucu uaaucacaga agacgccaac cauaaauuua caggauuaau aggaauguua      300

uaugcaaugu cacgacuagg uagagaagac acaauaaaaa uacuaagaga cgcaggcuau      360

cacguaaaag caaauggagu agacguaacc acacacagac aagacauaaa uggaaaagaa      420

augaaauuug aaguauuaac acuagcauca cuaacaacag aaauacaaau caacauagaa      480

auagaaucaa gaaaaagcua caaaaaaaug uuaaaagaaa ugggagaagu cgcaccagaa      540

uauagacaug auucaccaga cugcggaaug auaauacuau gcauagcagc ccuaguaauu      600

acaaaacuag cagcaggaga cagaagcgga uuaacagcag uaauaagaag agcaaacaac      660

guacuaaaaa acgaaaugaa aagauauaaa ggauuauuac caaaagacau agcaaacuca      720

uucuaugaag uauucgaaaa acacccccac uuuauagacg ucuucguaca cuucggaaua      780

gcccaaucau ccacaagagg aggaucaaga gucgaaggaa uauucgcagg auuauucaug      840

aacgcauaug gcgcaggaca aguaaugcua agauggggag uacuagcaaa auccgucaaa      900

aacauaaugc uaggacacgc aucaguucaa gcagaaaugg aacaaguagu agaaguauac      960

gaauacgccc aaaaacuagg aggagaagca ggauucuacc acauacuaaa uaauccaaaa     1020

gcaucacuac uaagccuaac ccaauuuccc cacuucucaa guguaguauu aggaaaugca     1080

gcuggacuag gaauaauggg agaauacaga ggaacaccaa gaaaccaaga cuuauacgac     1140

gcagcaaaag cauacgcaga gcaacuuaaa gaaaacggag uaauaaacua uagcguacua     1200

gacuuaacag cagaagaacu ggaagcaaua aaacaucaau uaaacccgaa agacaaugac     1260

guagaauuau aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10254
<211>  1547
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10254
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacucucgaa aguaaaacuc      120

aacgacaccc ucaacaaaga ccaacuccuu uccagcucca aauacaccau ccaacgaucc      180

accggagacu ccaucgacac gcccaacuac gacguccaga aacacaucaa caagcucugc      240

ggaaugcuac uaaucaccga ggacgccaac cacaaauuca caggacuuau agggaugcuc      300

uacgccaugu cccgccucgg acgcgaagac acaauaaaaa uccuacgaga cgccggcuac      360

cacguaaagg caaacggcgu cgacgucacc acacacagac aagacaucaa cggaaaggaa      420

augaaauucg aaguccucac ccucgccagc cuaaccaccg agauccaaau caacaucgaa      480

aucgaaucac gcaaauccua caagaaaaug cucaaagaaa ugggagaagu cgcccccgaa      540

uaccgucacg acucgcccga cugcggcaug auaauccuau gcaucgccgc acucgucaua      600

accaaacucg ccgccgguga ccgaucagga cugacagcag ucauccgccg agcaaacaac      660

gugcucaaaa acgaaaugaa acgcuacaaa ggccuacucc ccaaagacau cgccaacucc      720

uucuacgaag ucuucgaaaa acacccacac uucaucgacg ucuucgucca cuucggcauc      780

gcacaaucau caaccagagg cggcagccgc guugaaggca ucuucgcagg acucuuuaug      840

aacgccuacg gcgccggcca agucaugcuc cgcuggggcg uccuggcaaa aagcgucaaa      900

aacaucaugc uaggccacgc uagcguccaa gccgaaaugg aacaagucgu cgaaguuuac      960

gaguacgcac aaaaacucgg cggcgaagca ggcuucuacc acauccuaaa caaccccaaa     1020

gccucccugc uaucacucac ccaauucccc cacuucucca gcgucguccu cggcaacgcc     1080

gcaggacuag gcaucauggg agaauaccgc gggacaccgc gcaaccaaga ccucuacgac     1140

gccgccaaag ccuacgccga acaacucaaa gaaaacggcg ucauaaacua cucaguccuc     1200

gaccucaccg ccgaagaacu cgaagccauc aaacaccaac ucaacccaaa agacaacgac     1260

gucgaauuau aaggacuagu ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu     1320

auggucaucu guuccuguua gaaggcuaug cagcauauua uauacuaugc gcauguuaug     1380

aaaugcauaa uaaaaaauuu uaaaaaaucu aaaagaucua aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1500

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1547


<210>  10255
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10255
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcucuua gcaaagucaa guugaaugau      120

acacucaaca aagaucaacu ucugucaucc agcaaauaca ccauccaacg gagcacagga      180

gauaguauug auacuccuaa uuaugaugug cagaaacaca ucaauaaguu auguggcaug      240

uuauuaauca cagaagaugc uaaucauaaa uucacugggu uaauagguau guuauaugcg      300

augucuaggu uaggaagaga agacaccaua aaaauacuca gagaugcggg auaucaugua      360

aaagcaaaug gaguagaugu aacaacacau cgucaagaca uuaauggaaa agaaaugaaa      420

uuugaagugu uaacauuggc aagcuuaaca acugaaauuc aaaucaacau ugagauagaa      480

ucuagaaaau ccuacaaaaa aaugcuaaaa gaaaugggag agguagcucc agaauacagg      540

caugacucuc cugauugugg gaugauaaua uuauguauag cagcauuagu aauaacuaaa      600

uuagcagcag gggacagauc uggucuuaca gccgugauua ggagagcuaa uaauguccua      660

aaaaaugaaa ugaaacguua caaaggcuua cuacccaagg acauagccaa cagcuucuau      720

gaaguguuug aaaaacaucc ccacuuuaua gauguuuuug uucauuuugg uauagcacaa      780

ucuucuacca gagguggcag uagaguugaa gggauuuuug caggauuguu uaugaaugcc      840

uauggugcag ggcaagugau guuacggugg ggagucuuag caaaaucagu uaaaaauauu      900

auguuaggac augcuagugu gcaagcagaa auggaacaag uuguugaggu uuaugaauau      960

gcccaaaaau ugggugguga agcaggauuc uaccauauau ugaacaaccc aaaagcauca     1020

uuauuaucuu ugacucaauu uccucacuuc uccaguguag uauuaggcaa ugcugcuggc     1080

cuaggcauaa ugggagagua cagagguaca ccgaggaauc aagaucuaua ugaugcagca     1140

aaggcauaug cugaacaacu caaagaaaau ggugugauua acuacagugu acuagacuug     1200

acagcagaag aacuagaggc uaucaaacau cagcuuaauc caaaagauaa ugauguagag     1260

cuuugaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10256
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10256
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcucaacgac      120

acccugaaca aggaccagcu gcucuccagc uccaaguaca ccauccagcg cagcaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu gugcgggaug      240

cugcucauca ccgaggacgc caaccacaag uucaccggcc ugaucgggau gcuguacgcg      300

augagccggc ucggccgcga ggacacgauc aagauccugc gggacgccgg guaccacgug      360

aaggccaacg gcguggacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccucgc cucccugacg accgagaucc agaucaacau cgagaucgag      480

agccggaagu ccuacaagaa gaugcugaag gagauggggg agguggcccc ggaguaccgc      540

cacgacagcc ccgacugcgg caugaucauc cucugcaucg cggcccuggu caucaccaag      600

cuggccgccg gggaccgguc cggccucacc gcggugaucc gccgggccaa caacgugcug      660

aagaacgaga ugaagcgcua caaggggcug cuccccaagg acaucgccaa cagcuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

uccagcacgc ggggcggguc ccgcgucgag ggcaucuucg ccgggcuguu caugaacgcg      840

uacggcgccg gccaggugau gcugcggugg ggcgugcucg ccaagagcgu caagaacauc      900

augcuggggc acgccuccgu gcaggccgag auggagcagg ucguggaggu guacgaguac      960

gcgcagaagc ucgggggcga ggccggguuc uaccacaucc ugaacaaccc gaaggccagc     1020

cugcuguccc ucacccaguu cccccacuuc agcagcgugg uccugggcaa cgccgccggc     1080

cuggggauca ugggcgagua ccgcgggacg ccccggaacc aggaccucua cgacgcggcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacuccgu gcuggaccuc     1200

accgccgagg agcuggaggc gaucaagcac cagcugaacc ccaaggacaa cgacgucgag     1260

cucugaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10257
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10257
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccucu ccaaggucaa gcucaacgac      120

acccucaaca aggaccagcu ccucuccucc uccaaguaca ccauccagcg cuccaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu cugcggcaug      240

cuccucauca ccgaggacgc caaccacaag uucaccggcc ucaucggcau gcucuacgcc      300

augucccgcc ucggccgcga ggacaccauc aagauccucc gcgacgccgg cuaccacguc      360

aaggccaacg gcgucgacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggucc ucacccucgc cucccucacc accgagaucc agaucaacau cgagaucgag      480

ucccgcaagu ccuacaagaa gaugcucaag gagaugggcg aggucgcccc cgaguaccgc      540

cacgacuccc ccgacugcgg caugaucauc cucugcaucg ccgcccucgu caucaccaag      600

cucgccgccg gcgaccgcuc cggccucacc gccgucaucc gccgcgccaa caacguccuc      660

aagaacgaga ugaagcgcua caagggccuc cuccccaagg acaucgccaa cuccuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacgucuucg uccacuucgg caucgcccag      780

uccuccaccc gcggcggcuc ccgcgucgag ggcaucuucg ccggccucuu caugaacgcc      840

uacggcgccg gccaggucau gcuccgcugg ggcguccucg ccaaguccgu caagaacauc      900

augcucggcc acgccuccgu ccaggccgag auggagcagg ucgucgaggu cuacgaguac      960

gcccagaagc ucggcggcga ggccggcuuc uaccacaucc ucaacaaccc caaggccucc     1020

cuccucuccc ucacccaguu cccccacuuc uccuccgucg uccucggcaa cgccgccggc     1080

cucggcauca ugggcgagua ccgcggcacc ccccgcaacc aggaccucua cgacgccgcc     1140

aaggccuacg ccgagcagcu caaggagaac ggcgucauca acuacuccgu ccucgaccuc     1200

accgccgagg agcucgaggc caucaagcac cagcucaacc ccaaggacaa cgacgucgag     1260

cucugaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10258
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10258
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccuuaaua aggaucagcu guuguccucu ucaaaauaca caauccaaag aaguacuggc      180

gacagcauug auacgcccaa cuaugacguc cagaagcaca uaaauaaauu augcgggaug      240

cugcuaauca ccgaggaugc uaaccauaag uucacaggac ucauugguau gcuguacgca      300

auguccaggc uuggccggga agacacuauc aagauucugc gcgaugccgg guaucacguu      360

aaagcgaaug gaguggacgu aaccacacau cgacaggaua ucaacggcaa ggagaugaaa      420

uuugaagugu ugacccucgc uucucugacu acagagauac agaucaauau ugaaaucgag      480

ucgcguaagu cauacaaaaa gaugcugaag gagaugggug aagucgcccc ugaguauaga      540

cacgacagcc cagauugugg gaugauuauc cucugcauag cagccuuagu gauuaccaaa      600

cuggcugcag gagacaggag uggccuuacg gccguuaucc ggcgcgcuaa caauguguug      660

aagaacgaaa ugaaaagaua caagggccug cuaccgaaag auauugccaa uuccuucuau      720

gaggucuuug agaagcaucc ccacuucauc gacguguuug uacacuucgg gaucgcgcaa      780

ucuagcacua ggggagguuc ccggguugaa ggcauuuuug caggacucuu caugaacgcc      840

uacggggcug gccaggugau gcugcgcugg gguguccuug ccaaaucagu gaagaauaua      900

augcuggggc augcaagugu gcaggcugag auggaacagg ucguugaggu guacgaauau      960

gcccaaaagu ugggaggcga ggcgggcuuu uaccacaucc ucaacaaucc uaaagccagc     1020

cuguuaucuc ugacccaguu cccacauuuu uccucaguag ugcucgggaa cgcagcugga     1080

cuugguauua ugggcgagua ucgagggaca cccagaaacc aggaccugua cgaugccgcu     1140

aaggccuaug cagaacaguu gaaagagaau ggagucauca acuacagcgu gcuagaccug     1200

acugccgagg aacucgaagc uauaaagcac caacugaauc cuaaagauaa cgacguugag     1260

cuuugaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10259
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10259
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcugaacgac      120

acccugaaca aggaccagcu gcugagcagc agcaaguaca ccauccagag aagcaccggc      180

gacagcaucg acacccccaa cuacgacgug cagaagcaca ucaacaagcu gugcggcaug      240

cugcugauca ccgaggacgc caaccacaag uucaccggcc ugaucggcau gcuguacgcc      300

augagcagac ugggcagaga ggacaccauc aagauccuga gagacgccgg cuaccacgug      360

aaggccaacg gcguggacgu gaccacccac agacaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccuggc cagccugacc accgagaucc agaucaacau cgagaucgag      480

agcagaaaga gcuacaagaa gaugcugaag gagaugggcg agguggcccc cgaguacaga      540

cacgacagcc ccgacugcgg caugaucauc cugugcaucg ccgcccuggu gaucaccaag      600

cuggccgccg gcgacagaag cggccugacc gccgugauca gaagagccaa caacgugcug      660

aagaacgaga ugaagagaua caagggccug cugcccaagg acaucgccaa cagcuucuac      720

gagguguucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

agcagcacca gaggcggcag cagaguggag ggcaucuucg ccggccuguu caugaacgcc      840

uacggcgccg gccaggugau gcugagaugg ggcgugcugg ccaagagcgu gaagaacauc      900

augcugggcc acgccagcgu gcaggccgag auggagcagg ugguggaggu guacgaguac      960

gcccagaagc ugggcggcga ggccggcuuc uaccacaucc ugaacaaccc caaggccagc     1020

cugcugagcc ugacccaguu cccccacuuc agcagcgugg ugcugggcaa cgccgccggc     1080

cugggcauca ugggcgagua cagaggcacc cccagaaacc aggaccugua cgacgccgcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacagcgu gcuggaccug     1200

accgccgagg agcuggaggc caucaagcac cagcugaacc ccaaggacaa cgacguggag     1260

cugugaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10260
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10260
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccugaaua aggaucagcu ucuguccucu agcaaauaca caauccaaag auccacgggc      180

gacucuauug auacccccaa cuaugacguc cagaagcaca ucaauaaacu cugcgggaug      240

cugcuuauua cagaggaugc uaaccauaag uucaccggac ugaucggcau gcucuacgcc      300

augagccggc uggggcgcga agacacaauu aagauccuga gagaugcggg auaucacguu      360

aaagcuaaug gcguggacgu gaccacacau cggcaggaua ucaacgggaa ggagaugaaa      420

uuugaagucc ucacccuggc cucccuuacg accgagauuc agaucaauau ugaaaucgag      480

ucucgcaaga gcuacaaaaa gaugcugaag gagaugggag aaguggcccc ugaguauaga      540

cacgacuccc cggauugugg caugauuauc cucugcauug cugcccuggu uaucacaaaa      600

cuugcugccg gcgaccggag cgggcugacc gcggugaucc gcagagccaa caauguccuc      660

aagaacgaaa ugaaacggua caagggacug cugcccaaag auauugcuaa uucuuucuau      720

gagguguuug agaagcaucc ucacuucauc gacguuuuug ugcacuucgg cauugcccaa      780

uccagcacac gcgggggauc uagagucgaa ggcaucuuug cuggacucuu caugaacgcc      840

uacggggcgg gccaggugau gcugcggugg ggcgugcuug ccaaauccgu caagaauauu      900

augcuggggc augcuagcgu ucaggccgag auggaacagg ugguggaggu cuacgaauau      960

gcucaaaagc ucggaggcga ggccggguuu uaccacaucc ugaacaaucc caaagccucu     1020

cuucuguccc ucacccaguu cccucauuuu agcuccgugg uucugggaaa cgcugcgggc     1080

cuggggauca ugggagagua ucgcggcacg cccagaaacc aggaccucua cgaugccgcu     1140

aaggccuaug ccgaacagcu gaaagagaau ggcgugauua acuacucugu ccuugaccug     1200

acagcugagg aacucgaagc caucaagcac caacugaauc cuaaagauaa cgacguggag     1260

cuuugaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10261
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10261
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacuaa gcaaagucaa auuaaacgac      120

acauuaaaca aagaccaacu cuuaucauca ucaaaauaca caauacaaag aagcaccgga      180

gacaguaucg acacaccaaa cuaugacguc caaaaacaua uaaauaaauu augcggcaug      240

cucuuaauca cagaagacgc caaccauaaa uuuacaggau uaauaggaau guuauaugca      300

augucacgac uagguagaga agacacaaua aaaauacuaa gagacgcagg cuaucacgua      360

aaagcaaaug gaguagacgu aaccacacac agacaagaca uaaauggaaa agaaaugaaa      420

uuugaaguau uaacacuagc aucacuaaca acagaaauac aaaucaacau agaaauagaa      480

ucaagaaaaa gcuacaaaaa aauguuaaaa gaaaugggag aagucgcacc agaauauaga      540

caugauucac cagacugcgg aaugauaaua cuaugcauag cagcccuagu aauuacaaaa      600

cuagcagcag gagacagaag cggauuaaca gcaguaauaa gaagagcaaa caacguacua      660

aaaaacgaaa ugaaaagaua uaaaggauua uuaccaaaag acauagcaaa cucauucuau      720

gaaguauucg aaaaacaccc ccacuuuaua gacgucuucg uacacuucgg aauagcccaa      780

ucauccacaa gaggaggauc aagagucgaa ggaauauucg caggauuauu caugaacgca      840

uauggcgcag gacaaguaau gcuaagaugg ggaguacuag caaaauccgu caaaaacaua      900

augcuaggac acgcaucagu ucaagcagaa auggaacaag uaguagaagu auacgaauac      960

gcccaaaaac uaggaggaga agcaggauuc uaccacauac uaaauaaucc aaaagcauca     1020

cuacuaagcc uaacccaauu uccccacuuc ucaaguguag uauuaggaaa ugcagcugga     1080

cuaggaauaa ugggagaaua cagaggaaca ccaagaaacc aagacuuaua cgacgcagca     1140

aaagcauacg cagagcaacu uaaagaaaac ggaguaauaa acuauagcgu acuagacuua     1200

acagcagaag aacuggaagc aauaaaacau caauuaaacc cgaaagacaa ugacguagaa     1260

uuauaaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10262
<211>  1465
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10262
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacucu cgaaaguaaa acucaacgac      120

acccucaaca aagaccaacu ccuuuccagc uccaaauaca ccauccaacg auccaccgga      180

gacuccaucg acacgcccaa cuacgacguc cagaaacaca ucaacaagcu cugcggaaug      240

cuacuaauca ccgaggacgc caaccacaaa uucacaggac uuauagggau gcucuacgcc      300

augucccgcc ucggacgcga agacacaaua aaaauccuac gagacgccgg cuaccacgua      360

aaggcaaacg gcgucgacgu caccacacac agacaagaca ucaacggaaa ggaaaugaaa      420

uucgaagucc ucacccucgc cagccuaacc accgagaucc aaaucaacau cgaaaucgaa      480

ucacgcaaau ccuacaagaa aaugcucaaa gaaaugggag aagucgcccc cgaauaccgu      540

cacgacucgc ccgacugcgg caugauaauc cuaugcaucg ccgcacucgu cauaaccaaa      600

cucgccgccg gugaccgauc aggacugaca gcagucaucc gccgagcaaa caacgugcuc      660

aaaaacgaaa ugaaacgcua caaaggccua cuccccaaag acaucgccaa cuccuucuac      720

gaagucuucg aaaaacaccc acacuucauc gacgucuucg uccacuucgg caucgcacaa      780

ucaucaacca gaggcggcag ccgcguugaa ggcaucuucg caggacucuu uaugaacgcc      840

uacggcgccg gccaagucau gcuccgcugg ggcguccugg caaaaagcgu caaaaacauc      900

augcuaggcc acgcuagcgu ccaagccgaa auggaacaag ucgucgaagu uuacgaguac      960

gcacaaaaac ucggcggcga agcaggcuuc uaccacaucc uaaacaaccc caaagccucc     1020

cugcuaucac ucacccaauu cccccacuuc uccagcgucg uccucggcaa cgccgcagga     1080

cuaggcauca ugggagaaua ccgcgggaca ccgcgcaacc aagaccucua cgacgccgcc     1140

aaagccuacg ccgaacaacu caaagaaaac ggcgucauaa acuacucagu ccucgaccuc     1200

accgccgaag aacucgaagc caucaaacac caacucaacc caaaagacaa cgacgucgaa     1260

uuauaaggac uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua     1320

gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1440

ggcucuuuuc agagccacca gaauu                                           1465


<210>  10263
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10263
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcucuuag caaagucaag      120

uugaaugaua cacucaacaa agaucaacuu cugucaucca gcaaauacac cauccaacgg      180

agcacaggag auaguauuga uacuccuaau uaugaugugc agaaacacau caauaaguua      240

uguggcaugu uauuaaucac agaagaugcu aaucauaaau ucacuggguu aauagguaug      300

uuauaugcga ugucuagguu aggaagagaa gacaccauaa aaauacucag agaugcggga      360

uaucauguaa aagcaaaugg aguagaugua acaacacauc gucaagacau uaauggaaaa      420

gaaaugaaau uugaaguguu aacauuggca agcuuaacaa cugaaauuca aaucaacauu      480

gagauagaau cuagaaaauc cuacaaaaaa augcuaaaag aaaugggaga gguagcucca      540

gaauacaggc augacucucc ugauuguggg augauaauau uauguauagc agcauuagua      600

auaacuaaau uagcagcagg ggacagaucu ggucuuacag ccgugauuag gagagcuaau      660

aauguccuaa aaaaugaaau gaaacguuac aaaggcuuac uacccaagga cauagccaac      720

agcuucuaug aaguguuuga aaaacauccc cacuuuauag auguuuuugu ucauuuuggu      780

auagcacaau cuucuaccag agguggcagu agaguugaag ggauuuuugc aggauuguuu      840

augaaugccu auggugcagg gcaagugaug uuacgguggg gagucuuagc aaaaucaguu      900

aaaaauauua uguuaggaca ugcuagugug caagcagaaa uggaacaagu uguugagguu      960

uaugaauaug cccaaaaauu ggguggugaa gcaggauucu accauauauu gaacaaccca     1020

aaagcaucau uauuaucuuu gacucaauuu ccucacuucu ccaguguagu auuaggcaau     1080

gcugcuggcc uaggcauaau gggagaguac agagguacac cgaggaauca agaucuauau     1140

gaugcagcaa aggcauaugc ugaacaacuc aaagaaaaug gugugauuaa cuacagugua     1200

cuagacuuga cagcagaaga acuagaggcu aucaaacauc agcuuaaucc aaaagauaau     1260

gauguagagc uuugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10264
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10264
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cucaacgaca cccugaacaa ggaccagcug cucuccagcu ccaaguacac cauccagcgc      180

agcaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcug      240

ugcgggaugc ugcucaucac cgaggacgcc aaccacaagu ucaccggccu gaucgggaug      300

cuguacgcga ugagccggcu cggccgcgag gacacgauca agauccugcg ggacgccggg      360

uaccacguga aggccaacgg cguggacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccucgcc ucccugacga ccgagaucca gaucaacauc      480

gagaucgaga gccggaaguc cuacaagaag augcugaagg agauggggga gguggccccg      540

gaguaccgcc acgacagccc cgacugcggc augaucaucc ucugcaucgc ggcccugguc      600

aucaccaagc uggccgccgg ggaccggucc ggccucaccg cggugauccg ccgggccaac      660

aacgugcuga agaacgagau gaagcgcuac aaggggcugc uccccaagga caucgccaac      720

agcuucuacg aggucuucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccagu ccagcacgcg gggcgggucc cgcgucgagg gcaucuucgc cgggcuguuc      840

augaacgcgu acggcgccgg ccaggugaug cugcgguggg gcgugcucgc caagagcguc      900

aagaacauca ugcuggggca cgccuccgug caggccgaga uggagcaggu cguggaggug      960

uacgaguacg cgcagaagcu cgggggcgag gccggguucu accacauccu gaacaacccg     1020

aaggccagcc ugcugucccu cacccaguuc ccccacuuca gcagcguggu ccugggcaac     1080

gccgccggcc uggggaucau gggcgaguac cgcgggacgc cccggaacca ggaccucuac     1140

gacgcggcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacuccgug     1200

cuggaccuca ccgccgagga gcuggaggcg aucaagcacc agcugaaccc caaggacaac     1260

gacgucgagc ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10265
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10265
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccucuc caaggucaag      120

cucaacgaca cccucaacaa ggaccagcuc cucuccuccu ccaaguacac cauccagcgc      180

uccaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcuc      240

ugcggcaugc uccucaucac cgaggacgcc aaccacaagu ucaccggccu caucggcaug      300

cucuacgcca ugucccgccu cggccgcgag gacaccauca agauccuccg cgacgccggc      360

uaccacguca aggccaacgg cgucgacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgagguccu cacccucgcc ucccucacca ccgagaucca gaucaacauc      480

gagaucgagu cccgcaaguc cuacaagaag augcucaagg agaugggcga ggucgccccc      540

gaguaccgcc acgacucccc cgacugcggc augaucaucc ucugcaucgc cgcccucguc      600

aucaccaagc ucgccgccgg cgaccgcucc ggccucaccg ccgucauccg ccgcgccaac      660

aacguccuca agaacgagau gaagcgcuac aagggccucc uccccaagga caucgccaac      720

uccuucuacg aggucuucga gaagcacccc cacuucaucg acgucuucgu ccacuucggc      780

aucgcccagu ccuccacccg cggcggcucc cgcgucgagg gcaucuucgc cggccucuuc      840

augaacgccu acggcgccgg ccaggucaug cuccgcuggg gcguccucgc caaguccguc      900

aagaacauca ugcucggcca cgccuccguc caggccgaga uggagcaggu cgucgagguc      960

uacgaguacg cccagaagcu cggcggcgag gccggcuucu accacauccu caacaacccc     1020

aaggccuccc uccucucccu cacccaguuc ccccacuucu ccuccgucgu ccucggcaac     1080

gccgccggcc ucggcaucau gggcgaguac cgcggcaccc cccgcaacca ggaccucuac     1140

gacgccgcca aggccuacgc cgagcagcuc aaggagaacg gcgucaucaa cuacuccguc     1200

cucgaccuca ccgccgagga gcucgaggcc aucaagcacc agcucaaccc caaggacaac     1260

gacgucgagc ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10266
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10266
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccuuaauaa ggaucagcug uuguccucuu caaaauacac aauccaaaga      180

aguacuggcg acagcauuga uacgcccaac uaugacgucc agaagcacau aaauaaauua      240

ugcgggaugc ugcuaaucac cgaggaugcu aaccauaagu ucacaggacu cauugguaug      300

cuguacgcaa uguccaggcu uggccgggaa gacacuauca agauucugcg cgaugccggg      360

uaucacguua aagcgaaugg aguggacgua accacacauc gacaggauau caacggcaag      420

gagaugaaau uugaaguguu gacccucgcu ucucugacua cagagauaca gaucaauauu      480

gaaaucgagu cgcguaaguc auacaaaaag augcugaagg agauggguga agucgccccu      540

gaguauagac acgacagccc agauuguggg augauuaucc ucugcauagc agccuuagug      600

auuaccaaac uggcugcagg agacaggagu ggccuuacgg ccguuauccg gcgcgcuaac      660

aauguguuga agaacgaaau gaaaagauac aagggccugc uaccgaaaga uauugccaau      720

uccuucuaug aggucuuuga gaagcauccc cacuucaucg acguguuugu acacuucggg      780

aucgcgcaau cuagcacuag gggagguucc cggguugaag gcauuuuugc aggacucuuc      840

augaacgccu acggggcugg ccaggugaug cugcgcuggg guguccuugc caaaucagug      900

aagaauauaa ugcuggggca ugcaagugug caggcugaga uggaacaggu cguugaggug      960

uacgaauaug cccaaaaguu gggaggcgag gcgggcuuuu accacauccu caacaauccu     1020

aaagccagcc uguuaucucu gacccaguuc ccacauuuuu ccucaguagu gcucgggaac     1080

gcagcuggac uugguauuau gggcgaguau cgagggacac ccagaaacca ggaccuguac     1140

gaugccgcua aggccuaugc agaacaguug aaagagaaug gagucaucaa cuacagcgug     1200

cuagaccuga cugccgagga acucgaagcu auaaagcacc aacugaaucc uaaagauaac     1260

gacguugagc uuugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10267
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10267
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cugaacgaca cccugaacaa ggaccagcug cugagcagca gcaaguacac cauccagaga      180

agcaccggcg acagcaucga cacccccaac uacgacgugc agaagcacau caacaagcug      240

ugcggcaugc ugcugaucac cgaggacgcc aaccacaagu ucaccggccu gaucggcaug      300

cuguacgcca ugagcagacu gggcagagag gacaccauca agauccugag agacgccggc      360

uaccacguga aggccaacgg cguggacgug accacccaca gacaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccuggcc agccugacca ccgagaucca gaucaacauc      480

gagaucgaga gcagaaagag cuacaagaag augcugaagg agaugggcga gguggccccc      540

gaguacagac acgacagccc cgacugcggc augaucaucc ugugcaucgc cgcccuggug      600

aucaccaagc uggccgccgg cgacagaagc ggccugaccg ccgugaucag aagagccaac      660

aacgugcuga agaacgagau gaagagauac aagggccugc ugcccaagga caucgccaac      720

agcuucuacg agguguucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccaga gcagcaccag aggcggcagc agaguggagg gcaucuucgc cggccuguuc      840

augaacgccu acggcgccgg ccaggugaug cugagauggg gcgugcuggc caagagcgug      900

aagaacauca ugcugggcca cgccagcgug caggccgaga uggagcaggu gguggaggug      960

uacgaguacg cccagaagcu gggcggcgag gccggcuucu accacauccu gaacaacccc     1020

aaggccagcc ugcugagccu gacccaguuc ccccacuuca gcagcguggu gcugggcaac     1080

gccgccggcc ugggcaucau gggcgaguac agaggcaccc ccagaaacca ggaccuguac     1140

gacgccgcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacagcgug     1200

cuggaccuga ccgccgagga gcuggaggcc aucaagcacc agcugaaccc caaggacaac     1260

gacguggagc ugugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10268
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10268
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccugaauaa ggaucagcuu cuguccucua gcaaauacac aauccaaaga      180

uccacgggcg acucuauuga uacccccaac uaugacgucc agaagcacau caauaaacuc      240

ugcgggaugc ugcuuauuac agaggaugcu aaccauaagu ucaccggacu gaucggcaug      300

cucuacgcca ugagccggcu ggggcgcgaa gacacaauua agauccugag agaugcggga      360

uaucacguua aagcuaaugg cguggacgug accacacauc ggcaggauau caacgggaag      420

gagaugaaau uugaaguccu cacccuggcc ucccuuacga ccgagauuca gaucaauauu      480

gaaaucgagu cucgcaagag cuacaaaaag augcugaagg agaugggaga aguggccccu      540

gaguauagac acgacucccc ggauuguggc augauuaucc ucugcauugc ugcccugguu      600

aucacaaaac uugcugccgg cgaccggagc gggcugaccg cggugauccg cagagccaac      660

aauguccuca agaacgaaau gaaacgguac aagggacugc ugcccaaaga uauugcuaau      720

ucuuucuaug agguguuuga gaagcauccu cacuucaucg acguuuuugu gcacuucggc      780

auugcccaau ccagcacacg cgggggaucu agagucgaag gcaucuuugc uggacucuuc      840

augaacgccu acggggcggg ccaggugaug cugcgguggg gcgugcuugc caaauccguc      900

aagaauauua ugcuggggca ugcuagcguu caggccgaga uggaacaggu gguggagguc      960

uacgaauaug cucaaaagcu cggaggcgag gccggguuuu accacauccu gaacaauccc     1020

aaagccucuc uucugucccu cacccaguuc ccucauuuua gcuccguggu ucugggaaac     1080

gcugcgggcc uggggaucau gggagaguau cgcggcacgc ccagaaacca ggaccucuac     1140

gaugccgcua aggccuaugc cgaacagcug aaagagaaug gcgugauuaa cuacucuguc     1200

cuugaccuga cagcugagga acucgaagcc aucaagcacc aacugaaucc uaaagauaac     1260

gacguggagc uuugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10269
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10269
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacuaag caaagucaaa      120

uuaaacgaca cauuaaacaa agaccaacuc uuaucaucau caaaauacac aauacaaaga      180

agcaccggag acaguaucga cacaccaaac uaugacgucc aaaaacauau aaauaaauua      240

ugcggcaugc ucuuaaucac agaagacgcc aaccauaaau uuacaggauu aauaggaaug      300

uuauaugcaa ugucacgacu agguagagaa gacacaauaa aaauacuaag agacgcaggc      360

uaucacguaa aagcaaaugg aguagacgua accacacaca gacaagacau aaauggaaaa      420

gaaaugaaau uugaaguauu aacacuagca ucacuaacaa cagaaauaca aaucaacaua      480

gaaauagaau caagaaaaag cuacaaaaaa auguuaaaag aaaugggaga agucgcacca      540

gaauauagac augauucacc agacugcgga augauaauac uaugcauagc agcccuagua      600

auuacaaaac uagcagcagg agacagaagc ggauuaacag caguaauaag aagagcaaac      660

aacguacuaa aaaacgaaau gaaaagauau aaaggauuau uaccaaaaga cauagcaaac      720

ucauucuaug aaguauucga aaaacacccc cacuuuauag acgucuucgu acacuucgga      780

auagcccaau cauccacaag aggaggauca agagucgaag gaauauucgc aggauuauuc      840

augaacgcau auggcgcagg acaaguaaug cuaagauggg gaguacuagc aaaauccguc      900

aaaaacauaa ugcuaggaca cgcaucaguu caagcagaaa uggaacaagu aguagaagua      960

uacgaauacg cccaaaaacu aggaggagaa gcaggauucu accacauacu aaauaaucca     1020

aaagcaucac uacuaagccu aacccaauuu ccccacuucu caaguguagu auuaggaaau     1080

gcagcuggac uaggaauaau gggagaauac agaggaacac caagaaacca agacuuauac     1140

gacgcagcaa aagcauacgc agagcaacuu aaagaaaacg gaguaauaaa cuauagcgua     1200

cuagacuuaa cagcagaaga acuggaagca auaaaacauc aauuaaaccc gaaagacaau     1260

gacguagaau uauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10270
<211>  1474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10270
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacucuc gaaaguaaaa      120

cucaacgaca cccucaacaa agaccaacuc cuuuccagcu ccaaauacac cauccaacga      180

uccaccggag acuccaucga cacgcccaac uacgacgucc agaaacacau caacaagcuc      240

ugcggaaugc uacuaaucac cgaggacgcc aaccacaaau ucacaggacu uauagggaug      300

cucuacgcca ugucccgccu cggacgcgaa gacacaauaa aaauccuacg agacgccggc      360

uaccacguaa aggcaaacgg cgucgacguc accacacaca gacaagacau caacggaaag      420

gaaaugaaau ucgaaguccu cacccucgcc agccuaacca ccgagaucca aaucaacauc      480

gaaaucgaau cacgcaaauc cuacaagaaa augcucaaag aaaugggaga agucgccccc      540

gaauaccguc acgacucgcc cgacugcggc augauaaucc uaugcaucgc cgcacucguc      600

auaaccaaac ucgccgccgg ugaccgauca ggacugacag cagucauccg ccgagcaaac      660

aacgugcuca aaaacgaaau gaaacgcuac aaaggccuac uccccaaaga caucgccaac      720

uccuucuacg aagucuucga aaaacaccca cacuucaucg acgucuucgu ccacuucggc      780

aucgcacaau caucaaccag aggcggcagc cgcguugaag gcaucuucgc aggacucuuu      840

augaacgccu acggcgccgg ccaagucaug cuccgcuggg gcguccuggc aaaaagcguc      900

aaaaacauca ugcuaggcca cgcuagcguc caagccgaaa uggaacaagu cgucgaaguu      960

uacgaguacg cacaaaaacu cggcggcgaa gcaggcuucu accacauccu aaacaacccc     1020

aaagccuccc ugcuaucacu cacccaauuc ccccacuucu ccagcgucgu ccucggcaac     1080

gccgcaggac uaggcaucau gggagaauac cgcgggacac cgcgcaacca agaccucuac     1140

gacgccgcca aagccuacgc cgaacaacuc aaagaaaacg gcgucauaaa cuacucaguc     1200

cucgaccuca ccgccgaaga acucgaagcc aucaaacacc aacucaaccc aaaagacaac     1260

gacgucgaau uauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga     1320

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     1440

ccccccaaag gcucuuuuca gagccaccag aauu                                 1474


<210>  10271
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10271
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcucuua gcaaagucaa guugaaugau      120

acacucaaca aagaucaacu ucugucaucc agcaaauaca ccauccaacg gagcacagga      180

gauaguauug auacuccuaa uuaugaugug cagaaacaca ucaauaaguu auguggcaug      240

uuauuaauca cagaagaugc uaaucauaaa uucacugggu uaauagguau guuauaugcg      300

augucuaggu uaggaagaga agacaccaua aaaauacuca gagaugcggg auaucaugua      360

aaagcaaaug gaguagaugu aacaacacau cgucaagaca uuaauggaaa agaaaugaaa      420

uuugaagugu uaacauuggc aagcuuaaca acugaaauuc aaaucaacau ugagauagaa      480

ucuagaaaau ccuacaaaaa aaugcuaaaa gaaaugggag agguagcucc agaauacagg      540

caugacucuc cugauugugg gaugauaaua uuauguauag cagcauuagu aauaacuaaa      600

uuagcagcag gggacagauc uggucuuaca gccgugauua ggagagcuaa uaauguccua      660

aaaaaugaaa ugaaacguua caaaggcuua cuacccaagg acauagccaa cagcuucuau      720

gaaguguuug aaaaacaucc ccacuuuaua gauguuuuug uucauuuugg uauagcacaa      780

ucuucuacca gagguggcag uagaguugaa gggauuuuug caggauuguu uaugaaugcc      840

uauggugcag ggcaagugau guuacggugg ggagucuuag caaaaucagu uaaaaauauu      900

auguuaggac augcuagugu gcaagcagaa auggaacaag uuguugaggu uuaugaauau      960

gcccaaaaau ugggugguga agcaggauuc uaccauauau ugaacaaccc aaaagcauca     1020

uuauuaucuu ugacucaauu uccucacuuc uccaguguag uauuaggcaa ugcugcuggc     1080

cuaggcauaa ugggagagua cagagguaca ccgaggaauc aagaucuaua ugaugcagca     1140

aaggcauaug cugaacaacu caaagaaaau ggugugauua acuacagugu acuagacuug     1200

acagcagaag aacuagaggc uaucaaacau cagcuuaauc caaaagauaa ugauguagag     1260

cuuugaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10272
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10272
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcucaacgac      120

acccugaaca aggaccagcu gcucuccagc uccaaguaca ccauccagcg cagcaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu gugcgggaug      240

cugcucauca ccgaggacgc caaccacaag uucaccggcc ugaucgggau gcuguacgcg      300

augagccggc ucggccgcga ggacacgauc aagauccugc gggacgccgg guaccacgug      360

aaggccaacg gcguggacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccucgc cucccugacg accgagaucc agaucaacau cgagaucgag      480

agccggaagu ccuacaagaa gaugcugaag gagauggggg agguggcccc ggaguaccgc      540

cacgacagcc ccgacugcgg caugaucauc cucugcaucg cggcccuggu caucaccaag      600

cuggccgccg gggaccgguc cggccucacc gcggugaucc gccgggccaa caacgugcug      660

aagaacgaga ugaagcgcua caaggggcug cuccccaagg acaucgccaa cagcuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

uccagcacgc ggggcggguc ccgcgucgag ggcaucuucg ccgggcuguu caugaacgcg      840

uacggcgccg gccaggugau gcugcggugg ggcgugcucg ccaagagcgu caagaacauc      900

augcuggggc acgccuccgu gcaggccgag auggagcagg ucguggaggu guacgaguac      960

gcgcagaagc ucgggggcga ggccggguuc uaccacaucc ugaacaaccc gaaggccagc     1020

cugcuguccc ucacccaguu cccccacuuc agcagcgugg uccugggcaa cgccgccggc     1080

cuggggauca ugggcgagua ccgcgggacg ccccggaacc aggaccucua cgacgcggcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacuccgu gcuggaccuc     1200

accgccgagg agcuggaggc gaucaagcac cagcugaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10273
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10273
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccucu ccaaggucaa gcucaacgac      120

acccucaaca aggaccagcu ccucuccucc uccaaguaca ccauccagcg cuccaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu cugcggcaug      240

cuccucauca ccgaggacgc caaccacaag uucaccggcc ucaucggcau gcucuacgcc      300

augucccgcc ucggccgcga ggacaccauc aagauccucc gcgacgccgg cuaccacguc      360

aaggccaacg gcgucgacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggucc ucacccucgc cucccucacc accgagaucc agaucaacau cgagaucgag      480

ucccgcaagu ccuacaagaa gaugcucaag gagaugggcg aggucgcccc cgaguaccgc      540

cacgacuccc ccgacugcgg caugaucauc cucugcaucg ccgcccucgu caucaccaag      600

cucgccgccg gcgaccgcuc cggccucacc gccgucaucc gccgcgccaa caacguccuc      660

aagaacgaga ugaagcgcua caagggccuc cuccccaagg acaucgccaa cuccuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacgucuucg uccacuucgg caucgcccag      780

uccuccaccc gcggcggcuc ccgcgucgag ggcaucuucg ccggccucuu caugaacgcc      840

uacggcgccg gccaggucau gcuccgcugg ggcguccucg ccaaguccgu caagaacauc      900

augcucggcc acgccuccgu ccaggccgag auggagcagg ucgucgaggu cuacgaguac      960

gcccagaagc ucggcggcga ggccggcuuc uaccacaucc ucaacaaccc caaggccucc     1020

cuccucuccc ucacccaguu cccccacuuc uccuccgucg uccucggcaa cgccgccggc     1080

cucggcauca ugggcgagua ccgcggcacc ccccgcaacc aggaccucua cgacgccgcc     1140

aaggccuacg ccgagcagcu caaggagaac ggcgucauca acuacuccgu ccucgaccuc     1200

accgccgagg agcucgaggc caucaagcac cagcucaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10274
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10274
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccuuaaua aggaucagcu guuguccucu ucaaaauaca caauccaaag aaguacuggc      180

gacagcauug auacgcccaa cuaugacguc cagaagcaca uaaauaaauu augcgggaug      240

cugcuaauca ccgaggaugc uaaccauaag uucacaggac ucauugguau gcuguacgca      300

auguccaggc uuggccggga agacacuauc aagauucugc gcgaugccgg guaucacguu      360

aaagcgaaug gaguggacgu aaccacacau cgacaggaua ucaacggcaa ggagaugaaa      420

uuugaagugu ugacccucgc uucucugacu acagagauac agaucaauau ugaaaucgag      480

ucgcguaagu cauacaaaaa gaugcugaag gagaugggug aagucgcccc ugaguauaga      540

cacgacagcc cagauugugg gaugauuauc cucugcauag cagccuuagu gauuaccaaa      600

cuggcugcag gagacaggag uggccuuacg gccguuaucc ggcgcgcuaa caauguguug      660

aagaacgaaa ugaaaagaua caagggccug cuaccgaaag auauugccaa uuccuucuau      720

gaggucuuug agaagcaucc ccacuucauc gacguguuug uacacuucgg gaucgcgcaa      780

ucuagcacua ggggagguuc ccggguugaa ggcauuuuug caggacucuu caugaacgcc      840

uacggggcug gccaggugau gcugcgcugg gguguccuug ccaaaucagu gaagaauaua      900

augcuggggc augcaagugu gcaggcugag auggaacagg ucguugaggu guacgaauau      960

gcccaaaagu ugggaggcga ggcgggcuuu uaccacaucc ucaacaaucc uaaagccagc     1020

cuguuaucuc ugacccaguu cccacauuuu uccucaguag ugcucgggaa cgcagcugga     1080

cuugguauua ugggcgagua ucgagggaca cccagaaacc aggaccugua cgaugccgcu     1140

aaggccuaug cagaacaguu gaaagagaau ggagucauca acuacagcgu gcuagaccug     1200

acugccgagg aacucgaagc uauaaagcac caacugaauc cuaaagauaa cgacguugag     1260

cuuugaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10275
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10275
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcugaacgac      120

acccugaaca aggaccagcu gcugagcagc agcaaguaca ccauccagag aagcaccggc      180

gacagcaucg acacccccaa cuacgacgug cagaagcaca ucaacaagcu gugcggcaug      240

cugcugauca ccgaggacgc caaccacaag uucaccggcc ugaucggcau gcuguacgcc      300

augagcagac ugggcagaga ggacaccauc aagauccuga gagacgccgg cuaccacgug      360

aaggccaacg gcguggacgu gaccacccac agacaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccuggc cagccugacc accgagaucc agaucaacau cgagaucgag      480

agcagaaaga gcuacaagaa gaugcugaag gagaugggcg agguggcccc cgaguacaga      540

cacgacagcc ccgacugcgg caugaucauc cugugcaucg ccgcccuggu gaucaccaag      600

cuggccgccg gcgacagaag cggccugacc gccgugauca gaagagccaa caacgugcug      660

aagaacgaga ugaagagaua caagggccug cugcccaagg acaucgccaa cagcuucuac      720

gagguguucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

agcagcacca gaggcggcag cagaguggag ggcaucuucg ccggccuguu caugaacgcc      840

uacggcgccg gccaggugau gcugagaugg ggcgugcugg ccaagagcgu gaagaacauc      900

augcugggcc acgccagcgu gcaggccgag auggagcagg ugguggaggu guacgaguac      960

gcccagaagc ugggcggcga ggccggcuuc uaccacaucc ugaacaaccc caaggccagc     1020

cugcugagcc ugacccaguu cccccacuuc agcagcgugg ugcugggcaa cgccgccggc     1080

cugggcauca ugggcgagua cagaggcacc cccagaaacc aggaccugua cgacgccgcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacagcgu gcuggaccug     1200

accgccgagg agcuggaggc caucaagcac cagcugaacc ccaaggacaa cgacguggag     1260

cugugaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10276
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10276
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccugaaua aggaucagcu ucuguccucu agcaaauaca caauccaaag auccacgggc      180

gacucuauug auacccccaa cuaugacguc cagaagcaca ucaauaaacu cugcgggaug      240

cugcuuauua cagaggaugc uaaccauaag uucaccggac ugaucggcau gcucuacgcc      300

augagccggc uggggcgcga agacacaauu aagauccuga gagaugcggg auaucacguu      360

aaagcuaaug gcguggacgu gaccacacau cggcaggaua ucaacgggaa ggagaugaaa      420

uuugaagucc ucacccuggc cucccuuacg accgagauuc agaucaauau ugaaaucgag      480

ucucgcaaga gcuacaaaaa gaugcugaag gagaugggag aaguggcccc ugaguauaga      540

cacgacuccc cggauugugg caugauuauc cucugcauug cugcccuggu uaucacaaaa      600

cuugcugccg gcgaccggag cgggcugacc gcggugaucc gcagagccaa caauguccuc      660

aagaacgaaa ugaaacggua caagggacug cugcccaaag auauugcuaa uucuuucuau      720

gagguguuug agaagcaucc ucacuucauc gacguuuuug ugcacuucgg cauugcccaa      780

uccagcacac gcgggggauc uagagucgaa ggcaucuuug cuggacucuu caugaacgcc      840

uacggggcgg gccaggugau gcugcggugg ggcgugcuug ccaaauccgu caagaauauu      900

augcuggggc augcuagcgu ucaggccgag auggaacagg ugguggaggu cuacgaauau      960

gcucaaaagc ucggaggcga ggccggguuu uaccacaucc ugaacaaucc caaagccucu     1020

cuucuguccc ucacccaguu cccucauuuu agcuccgugg uucugggaaa cgcugcgggc     1080

cuggggauca ugggagagua ucgcggcacg cccagaaacc aggaccucua cgaugccgcu     1140

aaggccuaug ccgaacagcu gaaagagaau ggcgugauua acuacucugu ccuugaccug     1200

acagcugagg aacucgaagc caucaagcac caacugaauc cuaaagauaa cgacguggag     1260

cuuugaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10277
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10277
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacuaa gcaaagucaa auuaaacgac      120

acauuaaaca aagaccaacu cuuaucauca ucaaaauaca caauacaaag aagcaccgga      180

gacaguaucg acacaccaaa cuaugacguc caaaaacaua uaaauaaauu augcggcaug      240

cucuuaauca cagaagacgc caaccauaaa uuuacaggau uaauaggaau guuauaugca      300

augucacgac uagguagaga agacacaaua aaaauacuaa gagacgcagg cuaucacgua      360

aaagcaaaug gaguagacgu aaccacacac agacaagaca uaaauggaaa agaaaugaaa      420

uuugaaguau uaacacuagc aucacuaaca acagaaauac aaaucaacau agaaauagaa      480

ucaagaaaaa gcuacaaaaa aauguuaaaa gaaaugggag aagucgcacc agaauauaga      540

caugauucac cagacugcgg aaugauaaua cuaugcauag cagcccuagu aauuacaaaa      600

cuagcagcag gagacagaag cggauuaaca gcaguaauaa gaagagcaaa caacguacua      660

aaaaacgaaa ugaaaagaua uaaaggauua uuaccaaaag acauagcaaa cucauucuau      720

gaaguauucg aaaaacaccc ccacuuuaua gacgucuucg uacacuucgg aauagcccaa      780

ucauccacaa gaggaggauc aagagucgaa ggaauauucg caggauuauu caugaacgca      840

uauggcgcag gacaaguaau gcuaagaugg ggaguacuag caaaauccgu caaaaacaua      900

augcuaggac acgcaucagu ucaagcagaa auggaacaag uaguagaagu auacgaauac      960

gcccaaaaac uaggaggaga agcaggauuc uaccacauac uaaauaaucc aaaagcauca     1020

cuacuaagcc uaacccaauu uccccacuuc ucaaguguag uauuaggaaa ugcagcugga     1080

cuaggaauaa ugggagaaua cagaggaaca ccaagaaacc aagacuuaua cgacgcagca     1140

aaagcauacg cagagcaacu uaaagaaaac ggaguaauaa acuauagcgu acuagacuua     1200

acagcagaag aacuggaagc aauaaaacau caauuaaacc cgaaagacaa ugacguagaa     1260

uuauaaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10278
<211>  1529
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10278
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacucu cgaaaguaaa acucaacgac      120

acccucaaca aagaccaacu ccuuuccagc uccaaauaca ccauccaacg auccaccgga      180

gacuccaucg acacgcccaa cuacgacguc cagaaacaca ucaacaagcu cugcggaaug      240

cuacuaauca ccgaggacgc caaccacaaa uucacaggac uuauagggau gcucuacgcc      300

augucccgcc ucggacgcga agacacaaua aaaauccuac gagacgccgg cuaccacgua      360

aaggcaaacg gcgucgacgu caccacacac agacaagaca ucaacggaaa ggaaaugaaa      420

uucgaagucc ucacccucgc cagccuaacc accgagaucc aaaucaacau cgaaaucgaa      480

ucacgcaaau ccuacaagaa aaugcucaaa gaaaugggag aagucgcccc cgaauaccgu      540

cacgacucgc ccgacugcgg caugauaauc cuaugcaucg ccgcacucgu cauaaccaaa      600

cucgccgccg gugaccgauc aggacugaca gcagucaucc gccgagcaaa caacgugcuc      660

aaaaacgaaa ugaaacgcua caaaggccua cuccccaaag acaucgccaa cuccuucuac      720

gaagucuucg aaaaacaccc acacuucauc gacgucuucg uccacuucgg caucgcacaa      780

ucaucaacca gaggcggcag ccgcguugaa ggcaucuucg caggacucuu uaugaacgcc      840

uacggcgccg gccaagucau gcuccgcugg ggcguccugg caaaaagcgu caaaaacauc      900

augcuaggcc acgcuagcgu ccaagccgaa auggaacaag ucgucgaagu uuacgaguac      960

gcacaaaaac ucggcggcga agcaggcuuc uaccacaucc uaaacaaccc caaagccucc     1020

cugcuaucac ucacccaauu cccccacuuc uccagcgucg uccucggcaa cgccgcagga     1080

cuaggcauca ugggagaaua ccgcgggaca ccgcgcaacc aagaccucua cgacgccgcc     1140

aaagccuacg ccgaacaacu caaagaaaac ggcgucauaa acuacucagu ccucgaccuc     1200

accgccgaag aacucgaagc caucaaacac caacucaacc caaaagacaa cgacgucgaa     1260

uuauaaggac uaguaauaag gaaacuguau gaaugucugu gggcaggaag ugaagagauc     1320

cuucuguaaa gguuuuugga auuaugucug cugaauaaua aacuuuuuug aaauaauaaa     1380

ucugguagaa aaaugagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc     1500

caaaggcucu uuucagagcc accagaauu                                       1529


<210>  10279
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10279
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcu      180

cuuagcaaag ucaaguugaa ugauacacuc aacaaagauc aacuucuguc auccagcaaa      240

uacaccaucc aacggagcac aggagauagu auugauacuc cuaauuauga ugugcagaaa      300

cacaucaaua aguuaugugg cauguuauua aucacagaag augcuaauca uaaauucacu      360

ggguuaauag guauguuaua ugcgaugucu agguuaggaa gagaagacac cauaaaaaua      420

cucagagaug cgggauauca uguaaaagca aauggaguag auguaacaac acaucgucaa      480

gacauuaaug gaaaagaaau gaaauuugaa guguuaacau uggcaagcuu aacaacugaa      540

auucaaauca acauugagau agaaucuaga aaauccuaca aaaaaaugcu aaaagaaaug      600

ggagagguag cuccagaaua caggcaugac ucuccugauu gugggaugau aauauuaugu      660

auagcagcau uaguaauaac uaaauuagca gcaggggaca gaucuggucu uacagccgug      720

auuaggagag cuaauaaugu ccuaaaaaau gaaaugaaac guuacaaagg cuuacuaccc      780

aaggacauag ccaacagcuu cuaugaagug uuugaaaaac auccccacuu uauagauguu      840

uuuguucauu uugguauagc acaaucuucu accagaggug gcaguagagu ugaagggauu      900

uuugcaggau uguuuaugaa ugccuauggu gcagggcaag ugauguuacg guggggaguc      960

uuagcaaaau caguuaaaaa uauuauguua ggacaugcua gugugcaagc agaaauggaa     1020

caaguuguug agguuuauga auaugcccaa aaauugggug gugaagcagg auucuaccau     1080

auauugaaca acccaaaagc aucauuauua ucuuugacuc aauuuccuca cuucuccagu     1140

guaguauuag gcaaugcugc uggccuaggc auaaugggag aguacagagg uacaccgagg     1200

aaucaagauc uauaugaugc agcaaaggca uaugcugaac aacucaaaga aaauggugug     1260

auuaacuaca guguacuaga cuugacagca gaagaacuag aggcuaucaa acaucagcuu     1320

aauccaaaag auaaugaugu agagcuuuga ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10280
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10280
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcucaa cgacacccug aacaaggacc agcugcucuc cagcuccaag      240

uacaccaucc agcgcagcac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcugugcgg gaugcugcuc aucaccgagg acgccaacca caaguucacc      360

ggccugaucg ggaugcugua cgcgaugagc cggcucggcc gcgaggacac gaucaagauc      420

cugcgggacg ccggguacca cgugaaggcc aacggcgugg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc ucgccucccu gacgaccgag      540

auccagauca acaucgagau cgagagccgg aaguccuaca agaagaugcu gaaggagaug      600

ggggaggugg ccccggagua ccgccacgac agccccgacu gcggcaugau cauccucugc      660

aucgcggccc uggucaucac caagcuggcc gccggggacc gguccggccu caccgcggug      720

auccgccggg ccaacaacgu gcugaagaac gagaugaagc gcuacaaggg gcugcucccc      780

aaggacaucg ccaacagcuu cuacgagguc uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccaguccagc acgcggggcg ggucccgcgu cgagggcauc      900

uucgccgggc uguucaugaa cgcguacggc gccggccagg ugaugcugcg guggggcgug      960

cucgccaaga gcgucaagaa caucaugcug gggcacgccu ccgugcaggc cgagauggag     1020

caggucgugg agguguacga guacgcgcag aagcucgggg gcgaggccgg guucuaccac     1080

auccugaaca acccgaaggc cagccugcug ucccucaccc aguuccccca cuucagcagc     1140

gugguccugg gcaacgccgc cggccugggg aucaugggcg aguaccgcgg gacgccccgg     1200

aaccaggacc ucuacgacgc ggccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuacu ccgugcugga ccucaccgcc gaggagcugg aggcgaucaa gcaccagcug     1320

aaccccaagg acaacgacgu cgagcucuga ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10281
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10281
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cucuccaagg ucaagcucaa cgacacccuc aacaaggacc agcuccucuc cuccuccaag      240

uacaccaucc agcgcuccac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcucugcgg caugcuccuc aucaccgagg acgccaacca caaguucacc      360

ggccucaucg gcaugcucua cgccaugucc cgccucggcc gcgaggacac caucaagauc      420

cuccgcgacg ccggcuacca cgucaaggcc aacggcgucg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag guccucaccc ucgccucccu caccaccgag      540

auccagauca acaucgagau cgagucccgc aaguccuaca agaagaugcu caaggagaug      600

ggcgaggucg cccccgagua ccgccacgac ucccccgacu gcggcaugau cauccucugc      660

aucgccgccc ucgucaucac caagcucgcc gccggcgacc gcuccggccu caccgccguc      720

auccgccgcg ccaacaacgu ccucaagaac gagaugaagc gcuacaaggg ccuccucccc      780

aaggacaucg ccaacuccuu cuacgagguc uucgagaagc acccccacuu caucgacguc      840

uucguccacu ucggcaucgc ccaguccucc acccgcggcg gcucccgcgu cgagggcauc      900

uucgccggcc ucuucaugaa cgccuacggc gccggccagg ucaugcuccg cuggggcguc      960

cucgccaagu ccgucaagaa caucaugcuc ggccacgccu ccguccaggc cgagauggag     1020

caggucgucg aggucuacga guacgcccag aagcucggcg gcgaggccgg cuucuaccac     1080

auccucaaca accccaaggc cucccuccuc ucccucaccc aguuccccca cuucuccucc     1140

gucguccucg gcaacgccgc cggccucggc aucaugggcg aguaccgcgg caccccccgc     1200

aaccaggacc ucuacgacgc cgccaaggcc uacgccgagc agcucaagga gaacggcguc     1260

aucaacuacu ccguccucga ccucaccgcc gaggagcucg aggccaucaa gcaccagcuc     1320

aaccccaagg acaacgacgu cgagcucuga ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10282
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10282
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccuu aauaaggauc agcuguuguc cucuucaaaa      240

uacacaaucc aaagaaguac uggcgacagc auugauacgc ccaacuauga cguccagaag      300

cacauaaaua aauuaugcgg gaugcugcua aucaccgagg augcuaacca uaaguucaca      360

ggacucauug guaugcugua cgcaaugucc aggcuuggcc gggaagacac uaucaagauu      420

cugcgcgaug ccggguauca cguuaaagcg aauggagugg acguaaccac acaucgacag      480

gauaucaacg gcaaggagau gaaauuugaa guguugaccc ucgcuucucu gacuacagag      540

auacagauca auauugaaau cgagucgcgu aagucauaca aaaagaugcu gaaggagaug      600

ggugaagucg ccccugagua uagacacgac agcccagauu gugggaugau uauccucugc      660

auagcagccu uagugauuac caaacuggcu gcaggagaca ggaguggccu uacggccguu      720

auccggcgcg cuaacaaugu guugaagaac gaaaugaaaa gauacaaggg ccugcuaccg      780

aaagauauug ccaauuccuu cuaugagguc uuugagaagc auccccacuu caucgacgug      840

uuuguacacu ucgggaucgc gcaaucuagc acuaggggag guucccgggu ugaaggcauu      900

uuugcaggac ucuucaugaa cgccuacggg gcuggccagg ugaugcugcg cugggguguc      960

cuugccaaau cagugaagaa uauaaugcug gggcaugcaa gugugcaggc ugagauggaa     1020

caggucguug agguguacga auaugcccaa aaguugggag gcgaggcggg cuuuuaccac     1080

auccucaaca auccuaaagc cagccuguua ucucugaccc aguucccaca uuuuuccuca     1140

guagugcucg ggaacgcagc uggacuuggu auuaugggcg aguaucgagg gacacccaga     1200

aaccaggacc uguacgaugc cgcuaaggcc uaugcagaac aguugaaaga gaauggaguc     1260

aucaacuaca gcgugcuaga ccugacugcc gaggaacucg aagcuauaaa gcaccaacug     1320

aauccuaaag auaacgacgu ugagcuuuga ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10283
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10283
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcugaa cgacacccug aacaaggacc agcugcugag cagcagcaag      240

uacaccaucc agagaagcac cggcgacagc aucgacaccc ccaacuacga cgugcagaag      300

cacaucaaca agcugugcgg caugcugcug aucaccgagg acgccaacca caaguucacc      360

ggccugaucg gcaugcugua cgccaugagc agacugggca gagaggacac caucaagauc      420

cugagagacg ccggcuacca cgugaaggcc aacggcgugg acgugaccac ccacagacag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc uggccagccu gaccaccgag      540

auccagauca acaucgagau cgagagcaga aagagcuaca agaagaugcu gaaggagaug      600

ggcgaggugg cccccgagua cagacacgac agccccgacu gcggcaugau cauccugugc      660

aucgccgccc uggugaucac caagcuggcc gccggcgaca gaagcggccu gaccgccgug      720

aucagaagag ccaacaacgu gcugaagaac gagaugaaga gauacaaggg ccugcugccc      780

aaggacaucg ccaacagcuu cuacgaggug uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccagagcagc accagaggcg gcagcagagu ggagggcauc      900

uucgccggcc uguucaugaa cgccuacggc gccggccagg ugaugcugag auggggcgug      960

cuggccaaga gcgugaagaa caucaugcug ggccacgcca gcgugcaggc cgagauggag     1020

cagguggugg agguguacga guacgcccag aagcugggcg gcgaggccgg cuucuaccac     1080

auccugaaca accccaaggc cagccugcug agccugaccc aguuccccca cuucagcagc     1140

guggugcugg gcaacgccgc cggccugggc aucaugggcg aguacagagg cacccccaga     1200

aaccaggacc uguacgacgc cgccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuaca gcgugcugga ccugaccgcc gaggagcugg aggccaucaa gcaccagcug     1320

aaccccaagg acaacgacgu ggagcuguga ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10284
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10284
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccug aauaaggauc agcuucuguc cucuagcaaa      240

uacacaaucc aaagauccac gggcgacucu auugauaccc ccaacuauga cguccagaag      300

cacaucaaua aacucugcgg gaugcugcuu auuacagagg augcuaacca uaaguucacc      360

ggacugaucg gcaugcucua cgccaugagc cggcuggggc gcgaagacac aauuaagauc      420

cugagagaug cgggauauca cguuaaagcu aauggcgugg acgugaccac acaucggcag      480

gauaucaacg ggaaggagau gaaauuugaa guccucaccc uggccucccu uacgaccgag      540

auucagauca auauugaaau cgagucucgc aagagcuaca aaaagaugcu gaaggagaug      600

ggagaagugg ccccugagua uagacacgac uccccggauu guggcaugau uauccucugc      660

auugcugccc ugguuaucac aaaacuugcu gccggcgacc ggagcgggcu gaccgcggug      720

auccgcagag ccaacaaugu ccucaagaac gaaaugaaac gguacaaggg acugcugccc      780

aaagauauug cuaauucuuu cuaugaggug uuugagaagc auccucacuu caucgacguu      840

uuugugcacu ucggcauugc ccaauccagc acacgcgggg gaucuagagu cgaaggcauc      900

uuugcuggac ucuucaugaa cgccuacggg gcgggccagg ugaugcugcg guggggcgug      960

cuugccaaau ccgucaagaa uauuaugcug gggcaugcua gcguucaggc cgagauggaa     1020

cagguggugg aggucuacga auaugcucaa aagcucggag gcgaggccgg guuuuaccac     1080

auccugaaca aucccaaagc cucucuucug ucccucaccc aguucccuca uuuuagcucc     1140

gugguucugg gaaacgcugc gggccugggg aucaugggag aguaucgcgg cacgcccaga     1200

aaccaggacc ucuacgaugc cgcuaaggcc uaugccgaac agcugaaaga gaauggcgug     1260

auuaacuacu cuguccuuga ccugacagcu gaggaacucg aagccaucaa gcaccaacug     1320

aauccuaaag auaacgacgu ggagcuuuga ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10285
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10285
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cuaagcaaag ucaaauuaaa cgacacauua aacaaagacc aacucuuauc aucaucaaaa      240

uacacaauac aaagaagcac cggagacagu aucgacacac caaacuauga cguccaaaaa      300

cauauaaaua aauuaugcgg caugcucuua aucacagaag acgccaacca uaaauuuaca      360

ggauuaauag gaauguuaua ugcaauguca cgacuaggua gagaagacac aauaaaaaua      420

cuaagagacg caggcuauca cguaaaagca aauggaguag acguaaccac acacagacaa      480

gacauaaaug gaaaagaaau gaaauuugaa guauuaacac uagcaucacu aacaacagaa      540

auacaaauca acauagaaau agaaucaaga aaaagcuaca aaaaaauguu aaaagaaaug      600

ggagaagucg caccagaaua uagacaugau ucaccagacu gcggaaugau aauacuaugc      660

auagcagccc uaguaauuac aaaacuagca gcaggagaca gaagcggauu aacagcagua      720

auaagaagag caaacaacgu acuaaaaaac gaaaugaaaa gauauaaagg auuauuacca      780

aaagacauag caaacucauu cuaugaagua uucgaaaaac acccccacuu uauagacguc      840

uucguacacu ucggaauagc ccaaucaucc acaagaggag gaucaagagu cgaaggaaua      900

uucgcaggau uauucaugaa cgcauauggc gcaggacaag uaaugcuaag auggggagua      960

cuagcaaaau ccgucaaaaa cauaaugcua ggacacgcau caguucaagc agaaauggaa     1020

caaguaguag aaguauacga auacgcccaa aaacuaggag gagaagcagg auucuaccac     1080

auacuaaaua auccaaaagc aucacuacua agccuaaccc aauuucccca cuucucaagu     1140

guaguauuag gaaaugcagc uggacuagga auaaugggag aauacagagg aacaccaaga     1200

aaccaagacu uauacgacgc agcaaaagca uacgcagagc aacuuaaaga aaacggagua     1260

auaaacuaua gcguacuaga cuuaacagca gaagaacugg aagcaauaaa acaucaauua     1320

aacccgaaag acaaugacgu agaauuauaa ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10286
<211>  1845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10286
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cucucgaaag uaaaacucaa cgacacccuc aacaaagacc aacuccuuuc cagcuccaaa      240

uacaccaucc aacgauccac cggagacucc aucgacacgc ccaacuacga cguccagaaa      300

cacaucaaca agcucugcgg aaugcuacua aucaccgagg acgccaacca caaauucaca      360

ggacuuauag ggaugcucua cgccaugucc cgccucggac gcgaagacac aauaaaaauc      420

cuacgagacg ccggcuacca cguaaaggca aacggcgucg acgucaccac acacagacaa      480

gacaucaacg gaaaggaaau gaaauucgaa guccucaccc ucgccagccu aaccaccgag      540

auccaaauca acaucgaaau cgaaucacgc aaauccuaca agaaaaugcu caaagaaaug      600

ggagaagucg cccccgaaua ccgucacgac ucgcccgacu gcggcaugau aauccuaugc      660

aucgccgcac ucgucauaac caaacucgcc gccggugacc gaucaggacu gacagcaguc      720

auccgccgag caaacaacgu gcucaaaaac gaaaugaaac gcuacaaagg ccuacucccc      780

aaagacaucg ccaacuccuu cuacgaaguc uucgaaaaac acccacacuu caucgacguc      840

uucguccacu ucggcaucgc acaaucauca accagaggcg gcagccgcgu ugaaggcauc      900

uucgcaggac ucuuuaugaa cgccuacggc gccggccaag ucaugcuccg cuggggcguc      960

cuggcaaaaa gcgucaaaaa caucaugcua ggccacgcua gcguccaagc cgaaauggaa     1020

caagucgucg aaguuuacga guacgcacaa aaacucggcg gcgaagcagg cuucuaccac     1080

auccuaaaca accccaaagc cucccugcua ucacucaccc aauuccccca cuucuccagc     1140

gucguccucg gcaacgccgc aggacuaggc aucaugggag aauaccgcgg gacaccgcgc     1200

aaccaagacc ucuacgacgc cgccaaagcc uacgccgaac aacucaaaga aaacggcguc     1260

auaaacuacu caguccucga ccucaccgcc gaagaacucg aagccaucaa acaccaacuc     1320

aacccaaaag acaacgacgu cgaauuauaa ggacuaguga agggaacacc caaauuuaau     1380

ucagccuuaa gcacaauuaa uuaagaguga aacguaauug uacaagcagu uggucaccca     1440

ccauagggca ugaucaacac cgcaaccuuu ccuuuuuccc ccagugauuc ugaaaaaccc     1500

cucuucccuu cagcuugcuu agauguucca aauuuaguaa gcuuaaggcg gccuacagaa     1560

gaaaaagaaa aaaaaggcca caaaaguucc cucucacuuu caguaaauaa aauaaaagca     1620

gcaacagaaa uaaagaaaua aaugaaauuc aaaaugaaau aaauauugug uugugcagca     1680

uuaaaaaauc aauaaaaauu aaaaaugagc aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1800

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1845


<210>  10287
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10287
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucuuagca aagucaaguu gaaugauaca cucaacaaag      120

aucaacuucu gucauccagc aaauacacca uccaacggag cacaggagau aguauugaua      180

cuccuaauua ugaugugcag aaacacauca auaaguuaug uggcauguua uuaaucacag      240

aagaugcuaa ucauaaauuc acuggguuaa uagguauguu auaugcgaug ucuagguuag      300

gaagagaaga caccauaaaa auacucagag augcgggaua ucauguaaaa gcaaauggag      360

uagauguaac aacacaucgu caagacauua auggaaaaga aaugaaauuu gaaguguuaa      420

cauuggcaag cuuaacaacu gaaauucaaa ucaacauuga gauagaaucu agaaaauccu      480

acaaaaaaau gcuaaaagaa augggagagg uagcuccaga auacaggcau gacucuccug      540

auugugggau gauaauauua uguauagcag cauuaguaau aacuaaauua gcagcagggg      600

acagaucugg ucuuacagcc gugauuagga gagcuaauaa uguccuaaaa aaugaaauga      660

aacguuacaa aggcuuacua cccaaggaca uagccaacag cuucuaugaa guguuugaaa      720

aacaucccca cuuuauagau guuuuuguuc auuuugguau agcacaaucu ucuaccagag      780

guggcaguag aguugaaggg auuuuugcag gauuguuuau gaaugccuau ggugcagggc      840

aagugauguu acggugggga gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug      900

cuagugugca agcagaaaug gaacaaguug uugagguuua ugaauaugcc caaaaauugg      960

guggugaagc aggauucuac cauauauuga acaacccaaa agcaucauua uuaucuuuga     1020

cucaauuucc ucacuucucc aguguaguau uaggcaaugc ugcuggccua ggcauaaugg     1080

gagaguacag agguacaccg aggaaucaag aucuauauga ugcagcaaag gcauaugcug     1140

aacaacucaa agaaaauggu gugauuaacu acaguguacu agacuugaca gcagaagaac     1200

uagaggcuau caaacaucag cuuaauccaa aagauaauga uguagagcuu ugaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10288
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10288
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu caacgacacc cugaacaagg      120

accagcugcu cuccagcucc aaguacacca uccagcgcag caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcugug cgggaugcug cucaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucgggaugcu guacgcgaug agccggcucg      300

gccgcgagga cacgaucaag auccugcggg acgccgggua ccacgugaag gccaacggcg      360

uggacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccucgccuc ccugacgacc gagauccaga ucaacaucga gaucgagagc cggaaguccu      480

acaagaagau gcugaaggag augggggagg uggccccgga guaccgccac gacagccccg      540

acugcggcau gaucauccuc ugcaucgcgg cccuggucau caccaagcug gccgccgggg      600

accgguccgg ccucaccgcg gugauccgcc gggccaacaa cgugcugaag aacgagauga      660

agcgcuacaa ggggcugcuc cccaaggaca ucgccaacag cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagucc agcacgcggg      780

gcgggucccg cgucgagggc aucuucgccg ggcuguucau gaacgcguac ggcgccggcc      840

aggugaugcu gcgguggggc gugcucgcca agagcgucaa gaacaucaug cuggggcacg      900

ccuccgugca ggccgagaug gagcaggucg uggaggugua cgaguacgcg cagaagcucg      960

ggggcgaggc cggguucuac cacauccuga acaacccgaa ggccagccug cugucccuca     1020

cccaguuccc ccacuucagc agcguggucc ugggcaacgc cgccggccug gggaucaugg     1080

gcgaguaccg cgggacgccc cggaaccagg accucuacga cgcggccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acuccgugcu ggaccucacc gccgaggagc     1200

uggaggcgau caagcaccag cugaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10289
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10289
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccucucca aggucaagcu caacgacacc cucaacaagg      120

accagcuccu cuccuccucc aaguacacca uccagcgcuc caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcucug cggcaugcuc cucaucaccg      240

aggacgccaa ccacaaguuc accggccuca ucggcaugcu cuacgccaug ucccgccucg      300

gccgcgagga caccaucaag auccuccgcg acgccggcua ccacgucaag gccaacggcg      360

ucgacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gagguccuca      420

cccucgccuc ccucaccacc gagauccaga ucaacaucga gaucgagucc cgcaaguccu      480

acaagaagau gcucaaggag augggcgagg ucgcccccga guaccgccac gacucccccg      540

acugcggcau gaucauccuc ugcaucgccg cccucgucau caccaagcuc gccgccggcg      600

accgcuccgg ccucaccgcc gucauccgcc gcgccaacaa cguccucaag aacgagauga      660

agcgcuacaa gggccuccuc cccaaggaca ucgccaacuc cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac gucuucgucc acuucggcau cgcccagucc uccacccgcg      780

gcggcucccg cgucgagggc aucuucgccg gccucuucau gaacgccuac ggcgccggcc      840

aggucaugcu ccgcuggggc guccucgcca aguccgucaa gaacaucaug cucggccacg      900

ccuccgucca ggccgagaug gagcaggucg ucgaggucua cgaguacgcc cagaagcucg      960

gcggcgaggc cggcuucuac cacauccuca acaaccccaa ggccucccuc cucucccuca     1020

cccaguuccc ccacuucucc uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg     1080

gcgaguaccg cggcaccccc cgcaaccagg accucuacga cgccgccaag gccuacgccg     1140

agcagcucaa ggagaacggc gucaucaacu acuccguccu cgaccucacc gccgaggagc     1200

ucgaggccau caagcaccag cucaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10290
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10290
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cuuaauaagg      120

aucagcuguu guccucuuca aaauacacaa uccaaagaag uacuggcgac agcauugaua      180

cgcccaacua ugacguccag aagcacauaa auaaauuaug cgggaugcug cuaaucaccg      240

aggaugcuaa ccauaaguuc acaggacuca uugguaugcu guacgcaaug uccaggcuug      300

gccgggaaga cacuaucaag auucugcgcg augccgggua ucacguuaaa gcgaauggag      360

uggacguaac cacacaucga caggauauca acggcaagga gaugaaauuu gaaguguuga      420

cccucgcuuc ucugacuaca gagauacaga ucaauauuga aaucgagucg cguaagucau      480

acaaaaagau gcugaaggag augggugaag ucgccccuga guauagacac gacagcccag      540

auugugggau gauuauccuc ugcauagcag ccuuagugau uaccaaacug gcugcaggag      600

acaggagugg ccuuacggcc guuauccggc gcgcuaacaa uguguugaag aacgaaauga      660

aaagauacaa gggccugcua ccgaaagaua uugccaauuc cuucuaugag gucuuugaga      720

agcaucccca cuucaucgac guguuuguac acuucgggau cgcgcaaucu agcacuaggg      780

gagguucccg gguugaaggc auuuuugcag gacucuucau gaacgccuac ggggcuggcc      840

aggugaugcu gcgcuggggu guccuugcca aaucagugaa gaauauaaug cuggggcaug      900

caagugugca ggcugagaug gaacaggucg uugaggugua cgaauaugcc caaaaguugg      960

gaggcgaggc gggcuuuuac cacauccuca acaauccuaa agccagccug uuaucucuga     1020

cccaguuccc acauuuuucc ucaguagugc ucgggaacgc agcuggacuu gguauuaugg     1080

gcgaguaucg agggacaccc agaaaccagg accuguacga ugccgcuaag gccuaugcag     1140

aacaguugaa agagaaugga gucaucaacu acagcgugcu agaccugacu gccgaggaac     1200

ucgaagcuau aaagcaccaa cugaauccua aagauaacga cguugagcuu ugaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10291
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10291
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu gaacgacacc cugaacaagg      120

accagcugcu gagcagcagc aaguacacca uccagagaag caccggcgac agcaucgaca      180

cccccaacua cgacgugcag aagcacauca acaagcugug cggcaugcug cugaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucggcaugcu guacgccaug agcagacugg      300

gcagagagga caccaucaag auccugagag acgccggcua ccacgugaag gccaacggcg      360

uggacgugac cacccacaga caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccuggccag ccugaccacc gagauccaga ucaacaucga gaucgagagc agaaagagcu      480

acaagaagau gcugaaggag augggcgagg uggcccccga guacagacac gacagccccg      540

acugcggcau gaucauccug ugcaucgccg cccuggugau caccaagcug gccgccggcg      600

acagaagcgg ccugaccgcc gugaucagaa gagccaacaa cgugcugaag aacgagauga      660

agagauacaa gggccugcug cccaaggaca ucgccaacag cuucuacgag guguucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagagc agcaccagag      780

gcggcagcag aguggagggc aucuucgccg gccuguucau gaacgccuac ggcgccggcc      840

aggugaugcu gagauggggc gugcuggcca agagcgugaa gaacaucaug cugggccacg      900

ccagcgugca ggccgagaug gagcaggugg uggaggugua cgaguacgcc cagaagcugg      960

gcggcgaggc cggcuucuac cacauccuga acaaccccaa ggccagccug cugagccuga     1020

cccaguuccc ccacuucagc agcguggugc ugggcaacgc cgccggccug ggcaucaugg     1080

gcgaguacag aggcaccccc agaaaccagg accuguacga cgccgccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acagcgugcu ggaccugacc gccgaggagc     1200

uggaggccau caagcaccag cugaacccca aggacaacga cguggagcug ugaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10292
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10292
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cugaauaagg      120

aucagcuucu guccucuagc aaauacacaa uccaaagauc cacgggcgac ucuauugaua      180

cccccaacua ugacguccag aagcacauca auaaacucug cgggaugcug cuuauuacag      240

aggaugcuaa ccauaaguuc accggacuga ucggcaugcu cuacgccaug agccggcugg      300

ggcgcgaaga cacaauuaag auccugagag augcgggaua ucacguuaaa gcuaauggcg      360

uggacgugac cacacaucgg caggauauca acgggaagga gaugaaauuu gaaguccuca      420

cccuggccuc ccuuacgacc gagauucaga ucaauauuga aaucgagucu cgcaagagcu      480

acaaaaagau gcugaaggag augggagaag uggccccuga guauagacac gacuccccgg      540

auuguggcau gauuauccuc ugcauugcug cccugguuau cacaaaacuu gcugccggcg      600

accggagcgg gcugaccgcg gugauccgca gagccaacaa uguccucaag aacgaaauga      660

aacgguacaa gggacugcug cccaaagaua uugcuaauuc uuucuaugag guguuugaga      720

agcauccuca cuucaucgac guuuuugugc acuucggcau ugcccaaucc agcacacgcg      780

ggggaucuag agucgaaggc aucuuugcug gacucuucau gaacgccuac ggggcgggcc      840

aggugaugcu gcgguggggc gugcuugcca aauccgucaa gaauauuaug cuggggcaug      900

cuagcguuca ggccgagaug gaacaggugg uggaggucua cgaauaugcu caaaagcucg      960

gaggcgaggc cggguuuuac cacauccuga acaaucccaa agccucucuu cugucccuca     1020

cccaguuccc ucauuuuagc uccgugguuc ugggaaacgc ugcgggccug gggaucaugg     1080

gagaguaucg cggcacgccc agaaaccagg accucuacga ugccgcuaag gccuaugccg     1140

aacagcugaa agagaauggc gugauuaacu acucuguccu ugaccugaca gcugaggaac     1200

ucgaagccau caagcaccaa cugaauccua aagauaacga cguggagcuu ugaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10293
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10293
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaagca aagucaaauu aaacgacaca uuaaacaaag      120

accaacucuu aucaucauca aaauacacaa uacaaagaag caccggagac aguaucgaca      180

caccaaacua ugacguccaa aaacauauaa auaaauuaug cggcaugcuc uuaaucacag      240

aagacgccaa ccauaaauuu acaggauuaa uaggaauguu auaugcaaug ucacgacuag      300

guagagaaga cacaauaaaa auacuaagag acgcaggcua ucacguaaaa gcaaauggag      360

uagacguaac cacacacaga caagacauaa auggaaaaga aaugaaauuu gaaguauuaa      420

cacuagcauc acuaacaaca gaaauacaaa ucaacauaga aauagaauca agaaaaagcu      480

acaaaaaaau guuaaaagaa augggagaag ucgcaccaga auauagacau gauucaccag      540

acugcggaau gauaauacua ugcauagcag cccuaguaau uacaaaacua gcagcaggag      600

acagaagcgg auuaacagca guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga      660

aaagauauaa aggauuauua ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa      720

aacaccccca cuuuauagac gucuucguac acuucggaau agcccaauca uccacaagag      780

gaggaucaag agucgaagga auauucgcag gauuauucau gaacgcauau ggcgcaggac      840

aaguaaugcu aagaugggga guacuagcaa aauccgucaa aaacauaaug cuaggacacg      900

caucaguuca agcagaaaug gaacaaguag uagaaguaua cgaauacgcc caaaaacuag      960

gaggagaagc aggauucuac cacauacuaa auaauccaaa agcaucacua cuaagccuaa     1020

cccaauuucc ccacuucuca aguguaguau uaggaaaugc agcuggacua ggaauaaugg     1080

gagaauacag aggaacacca agaaaccaag acuuauacga cgcagcaaaa gcauacgcag     1140

agcaacuuaa agaaaacgga guaauaaacu auagcguacu agacuuaaca gcagaagaac     1200

uggaagcaau aaaacaucaa uuaaacccga aagacaauga cguagaauua uaaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10294
<211>  1528
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10294
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacucucga aaguaaaacu caacgacacc cucaacaaag      120

accaacuccu uuccagcucc aaauacacca uccaacgauc caccggagac uccaucgaca      180

cgcccaacua cgacguccag aaacacauca acaagcucug cggaaugcua cuaaucaccg      240

aggacgccaa ccacaaauuc acaggacuua uagggaugcu cuacgccaug ucccgccucg      300

gacgcgaaga cacaauaaaa auccuacgag acgccggcua ccacguaaag gcaaacggcg      360

ucgacgucac cacacacaga caagacauca acggaaagga aaugaaauuc gaaguccuca      420

cccucgccag ccuaaccacc gagauccaaa ucaacaucga aaucgaauca cgcaaauccu      480

acaagaaaau gcucaaagaa augggagaag ucgcccccga auaccgucac gacucgcccg      540

acugcggcau gauaauccua ugcaucgccg cacucgucau aaccaaacuc gccgccggug      600

accgaucagg acugacagca gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga      660

aacgcuacaa aggccuacuc cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa      720

aacacccaca cuucaucgac gucuucgucc acuucggcau cgcacaauca ucaaccagag      780

gcggcagccg cguugaaggc aucuucgcag gacucuuuau gaacgccuac ggcgccggcc      840

aagucaugcu ccgcuggggc guccuggcaa aaagcgucaa aaacaucaug cuaggccacg      900

cuagcgucca agccgaaaug gaacaagucg ucgaaguuua cgaguacgca caaaaacucg      960

gcggcgaagc aggcuucuac cacauccuaa acaaccccaa agccucccug cuaucacuca     1020

cccaauuccc ccacuucucc agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg     1080

gagaauaccg cgggacaccg cgcaaccaag accucuacga cgccgccaaa gccuacgccg     1140

aacaacucaa agaaaacggc gucauaaacu acucaguccu cgaccucacc gccgaagaac     1200

ucgaagccau caaacaccaa cucaacccaa aagacaacga cgucgaauua uaaggacuag     1260

uggaagcauu uuccuggcug auuaaaagaa auuacucagc uauggucauc uguuccuguu     1320

agaaggcuau gcagcauauu auauacuaug cgcauguuau gaaaugcaua auaaaaaauu     1380

uuaaaaaauc uaaaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1500

aaaggcucuu uucagagcca ccagaauu                                        1528


<210>  10295
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10295
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcu      180

cuuagcaaag ucaaguugaa ugauacacuc aacaaagauc aacuucuguc auccagcaaa      240

uacaccaucc aacggagcac aggagauagu auugauacuc cuaauuauga ugugcagaaa      300

cacaucaaua aguuaugugg cauguuauua aucacagaag augcuaauca uaaauucacu      360

ggguuaauag guauguuaua ugcgaugucu agguuaggaa gagaagacac cauaaaaaua      420

cucagagaug cgggauauca uguaaaagca aauggaguag auguaacaac acaucgucaa      480

gacauuaaug gaaaagaaau gaaauuugaa guguuaacau uggcaagcuu aacaacugaa      540

auucaaauca acauugagau agaaucuaga aaauccuaca aaaaaaugcu aaaagaaaug      600

ggagagguag cuccagaaua caggcaugac ucuccugauu gugggaugau aauauuaugu      660

auagcagcau uaguaauaac uaaauuagca gcaggggaca gaucuggucu uacagccgug      720

auuaggagag cuaauaaugu ccuaaaaaau gaaaugaaac guuacaaagg cuuacuaccc      780

aaggacauag ccaacagcuu cuaugaagug uuugaaaaac auccccacuu uauagauguu      840

uuuguucauu uugguauagc acaaucuucu accagaggug gcaguagagu ugaagggauu      900

uuugcaggau uguuuaugaa ugccuauggu gcagggcaag ugauguuacg guggggaguc      960

uuagcaaaau caguuaaaaa uauuauguua ggacaugcua gugugcaagc agaaauggaa     1020

caaguuguug agguuuauga auaugcccaa aaauugggug gugaagcagg auucuaccau     1080

auauugaaca acccaaaagc aucauuauua ucuuugacuc aauuuccuca cuucuccagu     1140

guaguauuag gcaaugcugc uggccuaggc auaaugggag aguacagagg uacaccgagg     1200

aaucaagauc uauaugaugc agcaaaggca uaugcugaac aacucaaaga aaauggugug     1260

auuaacuaca guguacuaga cuugacagca gaagaacuag aggcuaucaa acaucagcuu     1320

aauccaaaag auaaugaugu agagcuuuga ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10296
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10296
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcucaa cgacacccug aacaaggacc agcugcucuc cagcuccaag      240

uacaccaucc agcgcagcac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcugugcgg gaugcugcuc aucaccgagg acgccaacca caaguucacc      360

ggccugaucg ggaugcugua cgcgaugagc cggcucggcc gcgaggacac gaucaagauc      420

cugcgggacg ccggguacca cgugaaggcc aacggcgugg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc ucgccucccu gacgaccgag      540

auccagauca acaucgagau cgagagccgg aaguccuaca agaagaugcu gaaggagaug      600

ggggaggugg ccccggagua ccgccacgac agccccgacu gcggcaugau cauccucugc      660

aucgcggccc uggucaucac caagcuggcc gccggggacc gguccggccu caccgcggug      720

auccgccggg ccaacaacgu gcugaagaac gagaugaagc gcuacaaggg gcugcucccc      780

aaggacaucg ccaacagcuu cuacgagguc uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccaguccagc acgcggggcg ggucccgcgu cgagggcauc      900

uucgccgggc uguucaugaa cgcguacggc gccggccagg ugaugcugcg guggggcgug      960

cucgccaaga gcgucaagaa caucaugcug gggcacgccu ccgugcaggc cgagauggag     1020

caggucgugg agguguacga guacgcgcag aagcucgggg gcgaggccgg guucuaccac     1080

auccugaaca acccgaaggc cagccugcug ucccucaccc aguuccccca cuucagcagc     1140

gugguccugg gcaacgccgc cggccugggg aucaugggcg aguaccgcgg gacgccccgg     1200

aaccaggacc ucuacgacgc ggccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuacu ccgugcugga ccucaccgcc gaggagcugg aggcgaucaa gcaccagcug     1320

aaccccaagg acaacgacgu cgagcucuga ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10297
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10297
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cucuccaagg ucaagcucaa cgacacccuc aacaaggacc agcuccucuc cuccuccaag      240

uacaccaucc agcgcuccac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcucugcgg caugcuccuc aucaccgagg acgccaacca caaguucacc      360

ggccucaucg gcaugcucua cgccaugucc cgccucggcc gcgaggacac caucaagauc      420

cuccgcgacg ccggcuacca cgucaaggcc aacggcgucg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag guccucaccc ucgccucccu caccaccgag      540

auccagauca acaucgagau cgagucccgc aaguccuaca agaagaugcu caaggagaug      600

ggcgaggucg cccccgagua ccgccacgac ucccccgacu gcggcaugau cauccucugc      660

aucgccgccc ucgucaucac caagcucgcc gccggcgacc gcuccggccu caccgccguc      720

auccgccgcg ccaacaacgu ccucaagaac gagaugaagc gcuacaaggg ccuccucccc      780

aaggacaucg ccaacuccuu cuacgagguc uucgagaagc acccccacuu caucgacguc      840

uucguccacu ucggcaucgc ccaguccucc acccgcggcg gcucccgcgu cgagggcauc      900

uucgccggcc ucuucaugaa cgccuacggc gccggccagg ucaugcuccg cuggggcguc      960

cucgccaagu ccgucaagaa caucaugcuc ggccacgccu ccguccaggc cgagauggag     1020

caggucgucg aggucuacga guacgcccag aagcucggcg gcgaggccgg cuucuaccac     1080

auccucaaca accccaaggc cucccuccuc ucccucaccc aguuccccca cuucuccucc     1140

gucguccucg gcaacgccgc cggccucggc aucaugggcg aguaccgcgg caccccccgc     1200

aaccaggacc ucuacgacgc cgccaaggcc uacgccgagc agcucaagga gaacggcguc     1260

aucaacuacu ccguccucga ccucaccgcc gaggagcucg aggccaucaa gcaccagcuc     1320

aaccccaagg acaacgacgu cgagcucuga ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10298
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10298
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccuu aauaaggauc agcuguuguc cucuucaaaa      240

uacacaaucc aaagaaguac uggcgacagc auugauacgc ccaacuauga cguccagaag      300

cacauaaaua aauuaugcgg gaugcugcua aucaccgagg augcuaacca uaaguucaca      360

ggacucauug guaugcugua cgcaaugucc aggcuuggcc gggaagacac uaucaagauu      420

cugcgcgaug ccggguauca cguuaaagcg aauggagugg acguaaccac acaucgacag      480

gauaucaacg gcaaggagau gaaauuugaa guguugaccc ucgcuucucu gacuacagag      540

auacagauca auauugaaau cgagucgcgu aagucauaca aaaagaugcu gaaggagaug      600

ggugaagucg ccccugagua uagacacgac agcccagauu gugggaugau uauccucugc      660

auagcagccu uagugauuac caaacuggcu gcaggagaca ggaguggccu uacggccguu      720

auccggcgcg cuaacaaugu guugaagaac gaaaugaaaa gauacaaggg ccugcuaccg      780

aaagauauug ccaauuccuu cuaugagguc uuugagaagc auccccacuu caucgacgug      840

uuuguacacu ucgggaucgc gcaaucuagc acuaggggag guucccgggu ugaaggcauu      900

uuugcaggac ucuucaugaa cgccuacggg gcuggccagg ugaugcugcg cugggguguc      960

cuugccaaau cagugaagaa uauaaugcug gggcaugcaa gugugcaggc ugagauggaa     1020

caggucguug agguguacga auaugcccaa aaguugggag gcgaggcggg cuuuuaccac     1080

auccucaaca auccuaaagc cagccuguua ucucugaccc aguucccaca uuuuuccuca     1140

guagugcucg ggaacgcagc uggacuuggu auuaugggcg aguaucgagg gacacccaga     1200

aaccaggacc uguacgaugc cgcuaaggcc uaugcagaac aguugaaaga gaauggaguc     1260

aucaacuaca gcgugcuaga ccugacugcc gaggaacucg aagcuauaaa gcaccaacug     1320

aauccuaaag auaacgacgu ugagcuuuga ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10299
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10299
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcugaa cgacacccug aacaaggacc agcugcugag cagcagcaag      240

uacaccaucc agagaagcac cggcgacagc aucgacaccc ccaacuacga cgugcagaag      300

cacaucaaca agcugugcgg caugcugcug aucaccgagg acgccaacca caaguucacc      360

ggccugaucg gcaugcugua cgccaugagc agacugggca gagaggacac caucaagauc      420

cugagagacg ccggcuacca cgugaaggcc aacggcgugg acgugaccac ccacagacag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc uggccagccu gaccaccgag      540

auccagauca acaucgagau cgagagcaga aagagcuaca agaagaugcu gaaggagaug      600

ggcgaggugg cccccgagua cagacacgac agccccgacu gcggcaugau cauccugugc      660

aucgccgccc uggugaucac caagcuggcc gccggcgaca gaagcggccu gaccgccgug      720

aucagaagag ccaacaacgu gcugaagaac gagaugaaga gauacaaggg ccugcugccc      780

aaggacaucg ccaacagcuu cuacgaggug uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccagagcagc accagaggcg gcagcagagu ggagggcauc      900

uucgccggcc uguucaugaa cgccuacggc gccggccagg ugaugcugag auggggcgug      960

cuggccaaga gcgugaagaa caucaugcug ggccacgcca gcgugcaggc cgagauggag     1020

cagguggugg agguguacga guacgcccag aagcugggcg gcgaggccgg cuucuaccac     1080

auccugaaca accccaaggc cagccugcug agccugaccc aguuccccca cuucagcagc     1140

guggugcugg gcaacgccgc cggccugggc aucaugggcg aguacagagg cacccccaga     1200

aaccaggacc uguacgacgc cgccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuaca gcgugcugga ccugaccgcc gaggagcugg aggccaucaa gcaccagcug     1320

aaccccaagg acaacgacgu ggagcuguga ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10300
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10300
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccug aauaaggauc agcuucuguc cucuagcaaa      240

uacacaaucc aaagauccac gggcgacucu auugauaccc ccaacuauga cguccagaag      300

cacaucaaua aacucugcgg gaugcugcuu auuacagagg augcuaacca uaaguucacc      360

ggacugaucg gcaugcucua cgccaugagc cggcuggggc gcgaagacac aauuaagauc      420

cugagagaug cgggauauca cguuaaagcu aauggcgugg acgugaccac acaucggcag      480

gauaucaacg ggaaggagau gaaauuugaa guccucaccc uggccucccu uacgaccgag      540

auucagauca auauugaaau cgagucucgc aagagcuaca aaaagaugcu gaaggagaug      600

ggagaagugg ccccugagua uagacacgac uccccggauu guggcaugau uauccucugc      660

auugcugccc ugguuaucac aaaacuugcu gccggcgacc ggagcgggcu gaccgcggug      720

auccgcagag ccaacaaugu ccucaagaac gaaaugaaac gguacaaggg acugcugccc      780

aaagauauug cuaauucuuu cuaugaggug uuugagaagc auccucacuu caucgacguu      840

uuugugcacu ucggcauugc ccaauccagc acacgcgggg gaucuagagu cgaaggcauc      900

uuugcuggac ucuucaugaa cgccuacggg gcgggccagg ugaugcugcg guggggcgug      960

cuugccaaau ccgucaagaa uauuaugcug gggcaugcua gcguucaggc cgagauggaa     1020

cagguggugg aggucuacga auaugcucaa aagcucggag gcgaggccgg guuuuaccac     1080

auccugaaca aucccaaagc cucucuucug ucccucaccc aguucccuca uuuuagcucc     1140

gugguucugg gaaacgcugc gggccugggg aucaugggag aguaucgcgg cacgcccaga     1200

aaccaggacc ucuacgaugc cgcuaaggcc uaugccgaac agcugaaaga gaauggcgug     1260

auuaacuacu cuguccuuga ccugacagcu gaggaacucg aagccaucaa gcaccaacug     1320

aauccuaaag auaacgacgu ggagcuuuga ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10301
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10301
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cuaagcaaag ucaaauuaaa cgacacauua aacaaagacc aacucuuauc aucaucaaaa      240

uacacaauac aaagaagcac cggagacagu aucgacacac caaacuauga cguccaaaaa      300

cauauaaaua aauuaugcgg caugcucuua aucacagaag acgccaacca uaaauuuaca      360

ggauuaauag gaauguuaua ugcaauguca cgacuaggua gagaagacac aauaaaaaua      420

cuaagagacg caggcuauca cguaaaagca aauggaguag acguaaccac acacagacaa      480

gacauaaaug gaaaagaaau gaaauuugaa guauuaacac uagcaucacu aacaacagaa      540

auacaaauca acauagaaau agaaucaaga aaaagcuaca aaaaaauguu aaaagaaaug      600

ggagaagucg caccagaaua uagacaugau ucaccagacu gcggaaugau aauacuaugc      660

auagcagccc uaguaauuac aaaacuagca gcaggagaca gaagcggauu aacagcagua      720

auaagaagag caaacaacgu acuaaaaaac gaaaugaaaa gauauaaagg auuauuacca      780

aaagacauag caaacucauu cuaugaagua uucgaaaaac acccccacuu uauagacguc      840

uucguacacu ucggaauagc ccaaucaucc acaagaggag gaucaagagu cgaaggaaua      900

uucgcaggau uauucaugaa cgcauauggc gcaggacaag uaaugcuaag auggggagua      960

cuagcaaaau ccgucaaaaa cauaaugcua ggacacgcau caguucaagc agaaauggaa     1020

caaguaguag aaguauacga auacgcccaa aaacuaggag gagaagcagg auucuaccac     1080

auacuaaaua auccaaaagc aucacuacua agccuaaccc aauuucccca cuucucaagu     1140

guaguauuag gaaaugcagc uggacuagga auaaugggag aauacagagg aacaccaaga     1200

aaccaagacu uauacgacgc agcaaaagca uacgcagagc aacuuaaaga aaacggagua     1260

auaaacuaua gcguacuaga cuuaacagca gaagaacugg aagcaauaaa acaucaauua     1320

aacccgaaag acaaugacgu agaauuauaa ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10302
<211>  1625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10302
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cucucgaaag uaaaacucaa cgacacccuc aacaaagacc aacuccuuuc cagcuccaaa      240

uacaccaucc aacgauccac cggagacucc aucgacacgc ccaacuacga cguccagaaa      300

cacaucaaca agcucugcgg aaugcuacua aucaccgagg acgccaacca caaauucaca      360

ggacuuauag ggaugcucua cgccaugucc cgccucggac gcgaagacac aauaaaaauc      420

cuacgagacg ccggcuacca cguaaaggca aacggcgucg acgucaccac acacagacaa      480

gacaucaacg gaaaggaaau gaaauucgaa guccucaccc ucgccagccu aaccaccgag      540

auccaaauca acaucgaaau cgaaucacgc aaauccuaca agaaaaugcu caaagaaaug      600

ggagaagucg cccccgaaua ccgucacgac ucgcccgacu gcggcaugau aauccuaugc      660

aucgccgcac ucgucauaac caaacucgcc gccggugacc gaucaggacu gacagcaguc      720

auccgccgag caaacaacgu gcucaaaaac gaaaugaaac gcuacaaagg ccuacucccc      780

aaagacaucg ccaacuccuu cuacgaaguc uucgaaaaac acccacacuu caucgacguc      840

uucguccacu ucggcaucgc acaaucauca accagaggcg gcagccgcgu ugaaggcauc      900

uucgcaggac ucuuuaugaa cgccuacggc gccggccaag ucaugcuccg cuggggcguc      960

cuggcaaaaa gcgucaaaaa caucaugcua ggccacgcua gcguccaagc cgaaauggaa     1020

caagucgucg aaguuuacga guacgcacaa aaacucggcg gcgaagcagg cuucuaccac     1080

auccuaaaca accccaaagc cucccugcua ucacucaccc aauuccccca cuucuccagc     1140

gucguccucg gcaacgccgc aggacuaggc aucaugggag aauaccgcgg gacaccgcgc     1200

aaccaagacc ucuacgacgc cgccaaagcc uacgccgaac aacucaaaga aaacggcguc     1260

auaaacuacu caguccucga ccucaccgcc gaagaacucg aagccaucaa acaccaacuc     1320

aacccaaaag acaacgacgu cgaauuauaa ggacuagugg aagcauuuuc cuggcugauu     1380

aaaagaaauu acucagcuau ggucaucugu uccuguuaga aggcuaugca gcauauuaua     1440

uacuaugcgc auguuaugaa augcauaaua aaaaauuuua aaaaaucuaa aagaucuaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1620

gaauu                                                                 1625


<210>  10303
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10303
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcucuuagca aagucaaguu gaaugauaca cucaacaaag aucaacuucu gucauccagc      180

aaauacacca uccaacggag cacaggagau aguauugaua cuccuaauua ugaugugcag      240

aaacacauca auaaguuaug uggcauguua uuaaucacag aagaugcuaa ucauaaauuc      300

acuggguuaa uagguauguu auaugcgaug ucuagguuag gaagagaaga caccauaaaa      360

auacucagag augcgggaua ucauguaaaa gcaaauggag uagauguaac aacacaucgu      420

caagacauua auggaaaaga aaugaaauuu gaaguguuaa cauuggcaag cuuaacaacu      480

gaaauucaaa ucaacauuga gauagaaucu agaaaauccu acaaaaaaau gcuaaaagaa      540

augggagagg uagcuccaga auacaggcau gacucuccug auugugggau gauaauauua      600

uguauagcag cauuaguaau aacuaaauua gcagcagggg acagaucugg ucuuacagcc      660

gugauuagga gagcuaauaa uguccuaaaa aaugaaauga aacguuacaa aggcuuacua      720

cccaaggaca uagccaacag cuucuaugaa guguuugaaa aacaucccca cuuuauagau      780

guuuuuguuc auuuugguau agcacaaucu ucuaccagag guggcaguag aguugaaggg      840

auuuuugcag gauuguuuau gaaugccuau ggugcagggc aagugauguu acggugggga      900

gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug cuagugugca agcagaaaug      960

gaacaaguug uugagguuua ugaauaugcc caaaaauugg guggugaagc aggauucuac     1020

cauauauuga acaacccaaa agcaucauua uuaucuuuga cucaauuucc ucacuucucc     1080

aguguaguau uaggcaaugc ugcuggccua ggcauaaugg gagaguacag agguacaccg     1140

aggaaucaag aucuauauga ugcagcaaag gcauaugcug aacaacucaa agaaaauggu     1200

gugauuaacu acaguguacu agacuugaca gcagaagaac uagaggcuau caaacaucag     1260

cuuaauccaa aagauaauga uguagagcuu ugaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10304
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10304
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcccugagca aggugaagcu caacgacacc cugaacaagg accagcugcu cuccagcucc      180

aaguacacca uccagcgcag caccggcgac uccaucgaca cccccaacua cgacguccag      240

aagcacauca acaagcugug cgggaugcug cucaucaccg aggacgccaa ccacaaguuc      300

accggccuga ucgggaugcu guacgcgaug agccggcucg gccgcgagga cacgaucaag      360

auccugcggg acgccgggua ccacgugaag gccaacggcg uggacgucac cacccaccgc      420

caggacauca acggcaagga gaugaaguuc gaggugcuga cccucgccuc ccugacgacc      480

gagauccaga ucaacaucga gaucgagagc cggaaguccu acaagaagau gcugaaggag      540

augggggagg uggccccgga guaccgccac gacagccccg acugcggcau gaucauccuc      600

ugcaucgcgg cccuggucau caccaagcug gccgccgggg accgguccgg ccucaccgcg      660

gugauccgcc gggccaacaa cgugcugaag aacgagauga agcgcuacaa ggggcugcuc      720

cccaaggaca ucgccaacag cuucuacgag gucuucgaga agcaccccca cuucaucgac      780

guguucgugc acuucggcau cgcccagucc agcacgcggg gcgggucccg cgucgagggc      840

aucuucgccg ggcuguucau gaacgcguac ggcgccggcc aggugaugcu gcgguggggc      900

gugcucgcca agagcgucaa gaacaucaug cuggggcacg ccuccgugca ggccgagaug      960

gagcaggucg uggaggugua cgaguacgcg cagaagcucg ggggcgaggc cggguucuac     1020

cacauccuga acaacccgaa ggccagccug cugucccuca cccaguuccc ccacuucagc     1080

agcguggucc ugggcaacgc cgccggccug gggaucaugg gcgaguaccg cgggacgccc     1140

cggaaccagg accucuacga cgcggccaag gccuacgccg agcagcugaa ggagaacggc     1200

gugaucaacu acuccgugcu ggaccucacc gccgaggagc uggaggcgau caagcaccag     1260

cugaacccca aggacaacga cgucgagcuc ugaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10305
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10305
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcccucucca aggucaagcu caacgacacc cucaacaagg accagcuccu cuccuccucc      180

aaguacacca uccagcgcuc caccggcgac uccaucgaca cccccaacua cgacguccag      240

aagcacauca acaagcucug cggcaugcuc cucaucaccg aggacgccaa ccacaaguuc      300

accggccuca ucggcaugcu cuacgccaug ucccgccucg gccgcgagga caccaucaag      360

auccuccgcg acgccggcua ccacgucaag gccaacggcg ucgacgucac cacccaccgc      420

caggacauca acggcaagga gaugaaguuc gagguccuca cccucgccuc ccucaccacc      480

gagauccaga ucaacaucga gaucgagucc cgcaaguccu acaagaagau gcucaaggag      540

augggcgagg ucgcccccga guaccgccac gacucccccg acugcggcau gaucauccuc      600

ugcaucgccg cccucgucau caccaagcuc gccgccggcg accgcuccgg ccucaccgcc      660

gucauccgcc gcgccaacaa cguccucaag aacgagauga agcgcuacaa gggccuccuc      720

cccaaggaca ucgccaacuc cuucuacgag gucuucgaga agcaccccca cuucaucgac      780

gucuucgucc acuucggcau cgcccagucc uccacccgcg gcggcucccg cgucgagggc      840

aucuucgccg gccucuucau gaacgccuac ggcgccggcc aggucaugcu ccgcuggggc      900

guccucgcca aguccgucaa gaacaucaug cucggccacg ccuccgucca ggccgagaug      960

gagcaggucg ucgaggucua cgaguacgcc cagaagcucg gcggcgaggc cggcuucuac     1020

cacauccuca acaaccccaa ggccucccuc cucucccuca cccaguuccc ccacuucucc     1080

uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg gcgaguaccg cggcaccccc     1140

cgcaaccagg accucuacga cgccgccaag gccuacgccg agcagcucaa ggagaacggc     1200

gucaucaacu acuccguccu cgaccucacc gccgaggagc ucgaggccau caagcaccag     1260

cucaacccca aggacaacga cgucgagcuc ugaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10306
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10306
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcccugagca aggugaaacu caacgacacc cuuaauaagg aucagcuguu guccucuuca      180

aaauacacaa uccaaagaag uacuggcgac agcauugaua cgcccaacua ugacguccag      240

aagcacauaa auaaauuaug cgggaugcug cuaaucaccg aggaugcuaa ccauaaguuc      300

acaggacuca uugguaugcu guacgcaaug uccaggcuug gccgggaaga cacuaucaag      360

auucugcgcg augccgggua ucacguuaaa gcgaauggag uggacguaac cacacaucga      420

caggauauca acggcaagga gaugaaauuu gaaguguuga cccucgcuuc ucugacuaca      480

gagauacaga ucaauauuga aaucgagucg cguaagucau acaaaaagau gcugaaggag      540

augggugaag ucgccccuga guauagacac gacagcccag auugugggau gauuauccuc      600

ugcauagcag ccuuagugau uaccaaacug gcugcaggag acaggagugg ccuuacggcc      660

guuauccggc gcgcuaacaa uguguugaag aacgaaauga aaagauacaa gggccugcua      720

ccgaaagaua uugccaauuc cuucuaugag gucuuugaga agcaucccca cuucaucgac      780

guguuuguac acuucgggau cgcgcaaucu agcacuaggg gagguucccg gguugaaggc      840

auuuuugcag gacucuucau gaacgccuac ggggcuggcc aggugaugcu gcgcuggggu      900

guccuugcca aaucagugaa gaauauaaug cuggggcaug caagugugca ggcugagaug      960

gaacaggucg uugaggugua cgaauaugcc caaaaguugg gaggcgaggc gggcuuuuac     1020

cacauccuca acaauccuaa agccagccug uuaucucuga cccaguuccc acauuuuucc     1080

ucaguagugc ucgggaacgc agcuggacuu gguauuaugg gcgaguaucg agggacaccc     1140

agaaaccagg accuguacga ugccgcuaag gccuaugcag aacaguugaa agagaaugga     1200

gucaucaacu acagcgugcu agaccugacu gccgaggaac ucgaagcuau aaagcaccaa     1260

cugaauccua aagauaacga cguugagcuu ugaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10307
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10307
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcccugagca aggugaagcu gaacgacacc cugaacaagg accagcugcu gagcagcagc      180

aaguacacca uccagagaag caccggcgac agcaucgaca cccccaacua cgacgugcag      240

aagcacauca acaagcugug cggcaugcug cugaucaccg aggacgccaa ccacaaguuc      300

accggccuga ucggcaugcu guacgccaug agcagacugg gcagagagga caccaucaag      360

auccugagag acgccggcua ccacgugaag gccaacggcg uggacgugac cacccacaga      420

caggacauca acggcaagga gaugaaguuc gaggugcuga cccuggccag ccugaccacc      480

gagauccaga ucaacaucga gaucgagagc agaaagagcu acaagaagau gcugaaggag      540

augggcgagg uggcccccga guacagacac gacagccccg acugcggcau gaucauccug      600

ugcaucgccg cccuggugau caccaagcug gccgccggcg acagaagcgg ccugaccgcc      660

gugaucagaa gagccaacaa cgugcugaag aacgagauga agagauacaa gggccugcug      720

cccaaggaca ucgccaacag cuucuacgag guguucgaga agcaccccca cuucaucgac      780

guguucgugc acuucggcau cgcccagagc agcaccagag gcggcagcag aguggagggc      840

aucuucgccg gccuguucau gaacgccuac ggcgccggcc aggugaugcu gagauggggc      900

gugcuggcca agagcgugaa gaacaucaug cugggccacg ccagcgugca ggccgagaug      960

gagcaggugg uggaggugua cgaguacgcc cagaagcugg gcggcgaggc cggcuucuac     1020

cacauccuga acaaccccaa ggccagccug cugagccuga cccaguuccc ccacuucagc     1080

agcguggugc ugggcaacgc cgccggccug ggcaucaugg gcgaguacag aggcaccccc     1140

agaaaccagg accuguacga cgccgccaag gccuacgccg agcagcugaa ggagaacggc     1200

gugaucaacu acagcgugcu ggaccugacc gccgaggagc uggaggccau caagcaccag     1260

cugaacccca aggacaacga cguggagcug ugaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10308
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10308
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcccugagca aggugaaacu caacgacacc cugaauaagg aucagcuucu guccucuagc      180

aaauacacaa uccaaagauc cacgggcgac ucuauugaua cccccaacua ugacguccag      240

aagcacauca auaaacucug cgggaugcug cuuauuacag aggaugcuaa ccauaaguuc      300

accggacuga ucggcaugcu cuacgccaug agccggcugg ggcgcgaaga cacaauuaag      360

auccugagag augcgggaua ucacguuaaa gcuaauggcg uggacgugac cacacaucgg      420

caggauauca acgggaagga gaugaaauuu gaaguccuca cccuggccuc ccuuacgacc      480

gagauucaga ucaauauuga aaucgagucu cgcaagagcu acaaaaagau gcugaaggag      540

augggagaag uggccccuga guauagacac gacuccccgg auuguggcau gauuauccuc      600

ugcauugcug cccugguuau cacaaaacuu gcugccggcg accggagcgg gcugaccgcg      660

gugauccgca gagccaacaa uguccucaag aacgaaauga aacgguacaa gggacugcug      720

cccaaagaua uugcuaauuc uuucuaugag guguuugaga agcauccuca cuucaucgac      780

guuuuugugc acuucggcau ugcccaaucc agcacacgcg ggggaucuag agucgaaggc      840

aucuuugcug gacucuucau gaacgccuac ggggcgggcc aggugaugcu gcgguggggc      900

gugcuugcca aauccgucaa gaauauuaug cuggggcaug cuagcguuca ggccgagaug      960

gaacaggugg uggaggucua cgaauaugcu caaaagcucg gaggcgaggc cggguuuuac     1020

cacauccuga acaaucccaa agccucucuu cugucccuca cccaguuccc ucauuuuagc     1080

uccgugguuc ugggaaacgc ugcgggccug gggaucaugg gagaguaucg cggcacgccc     1140

agaaaccagg accucuacga ugccgcuaag gccuaugccg aacagcugaa agagaauggc     1200

gugauuaacu acucuguccu ugaccugaca gcugaggaac ucgaagccau caagcaccaa     1260

cugaauccua aagauaacga cguggagcuu ugaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10309
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10309
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcacuaagca aagucaaauu aaacgacaca uuaaacaaag accaacucuu aucaucauca      180

aaauacacaa uacaaagaag caccggagac aguaucgaca caccaaacua ugacguccaa      240

aaacauauaa auaaauuaug cggcaugcuc uuaaucacag aagacgccaa ccauaaauuu      300

acaggauuaa uaggaauguu auaugcaaug ucacgacuag guagagaaga cacaauaaaa      360

auacuaagag acgcaggcua ucacguaaaa gcaaauggag uagacguaac cacacacaga      420

caagacauaa auggaaaaga aaugaaauuu gaaguauuaa cacuagcauc acuaacaaca      480

gaaauacaaa ucaacauaga aauagaauca agaaaaagcu acaaaaaaau guuaaaagaa      540

augggagaag ucgcaccaga auauagacau gauucaccag acugcggaau gauaauacua      600

ugcauagcag cccuaguaau uacaaaacua gcagcaggag acagaagcgg auuaacagca      660

guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga aaagauauaa aggauuauua      720

ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa aacaccccca cuuuauagac      780

gucuucguac acuucggaau agcccaauca uccacaagag gaggaucaag agucgaagga      840

auauucgcag gauuauucau gaacgcauau ggcgcaggac aaguaaugcu aagaugggga      900

guacuagcaa aauccgucaa aaacauaaug cuaggacacg caucaguuca agcagaaaug      960

gaacaaguag uagaaguaua cgaauacgcc caaaaacuag gaggagaagc aggauucuac     1020

cacauacuaa auaauccaaa agcaucacua cuaagccuaa cccaauuucc ccacuucuca     1080

aguguaguau uaggaaaugc agcuggacua ggaauaaugg gagaauacag aggaacacca     1140

agaaaccaag acuuauacga cgcagcaaaa gcauacgcag agcaacuuaa agaaaacgga     1200

guaauaaacu auagcguacu agacuuaaca gcagaagaac uggaagcaau aaaacaucaa     1260

uuaaacccga aagacaauga cguagaauua uaaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10310
<211>  1505
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10310
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gcacucucga aaguaaaacu caacgacacc cucaacaaag accaacuccu uuccagcucc      180

aaauacacca uccaacgauc caccggagac uccaucgaca cgcccaacua cgacguccag      240

aaacacauca acaagcucug cggaaugcua cuaaucaccg aggacgccaa ccacaaauuc      300

acaggacuua uagggaugcu cuacgccaug ucccgccucg gacgcgaaga cacaauaaaa      360

auccuacgag acgccggcua ccacguaaag gcaaacggcg ucgacgucac cacacacaga      420

caagacauca acggaaagga aaugaaauuc gaaguccuca cccucgccag ccuaaccacc      480

gagauccaaa ucaacaucga aaucgaauca cgcaaauccu acaagaaaau gcucaaagaa      540

augggagaag ucgcccccga auaccgucac gacucgcccg acugcggcau gauaauccua      600

ugcaucgccg cacucgucau aaccaaacuc gccgccggug accgaucagg acugacagca      660

gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga aacgcuacaa aggccuacuc      720

cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa aacacccaca cuucaucgac      780

gucuucgucc acuucggcau cgcacaauca ucaaccagag gcggcagccg cguugaaggc      840

aucuucgcag gacucuuuau gaacgccuac ggcgccggcc aagucaugcu ccgcuggggc      900

guccuggcaa aaagcgucaa aaacaucaug cuaggccacg cuagcgucca agccgaaaug      960

gaacaagucg ucgaaguuua cgaguacgca caaaaacucg gcggcgaagc aggcuucuac     1020

cacauccuaa acaaccccaa agccucccug cuaucacuca cccaauuccc ccacuucucc     1080

agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg gagaauaccg cgggacaccg     1140

cgcaaccaag accucuacga cgccgccaaa gccuacgccg aacaacucaa agaaaacggc     1200

gucauaaacu acucaguccu cgaccucacc gccgaagaac ucgaagccau caaacaccaa     1260

cucaacccaa aagacaacga cgucgaauua uaaggacuag uguccaccug ucccuccugg     1320

gcugcuggau ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1500

gaauu                                                                 1505


<210>  10311
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10311
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcucuuag caaagucaag      120

uugaaugaua cacucaacaa agaucaacuu cugucaucca gcaaauacac cauccaacgg      180

agcacaggag auaguauuga uacuccuaau uaugaugugc agaaacacau caauaaguua      240

uguggcaugu uauuaaucac agaagaugcu aaucauaaau ucacuggguu aauagguaug      300

uuauaugcga ugucuagguu aggaagagaa gacaccauaa aaauacucag agaugcggga      360

uaucauguaa aagcaaaugg aguagaugua acaacacauc gucaagacau uaauggaaaa      420

gaaaugaaau uugaaguguu aacauuggca agcuuaacaa cugaaauuca aaucaacauu      480

gagauagaau cuagaaaauc cuacaaaaaa augcuaaaag aaaugggaga gguagcucca      540

gaauacaggc augacucucc ugauuguggg augauaauau uauguauagc agcauuagua      600

auaacuaaau uagcagcagg ggacagaucu ggucuuacag ccgugauuag gagagcuaau      660

aauguccuaa aaaaugaaau gaaacguuac aaaggcuuac uacccaagga cauagccaac      720

agcuucuaug aaguguuuga aaaacauccc cacuuuauag auguuuuugu ucauuuuggu      780

auagcacaau cuucuaccag agguggcagu agaguugaag ggauuuuugc aggauuguuu      840

augaaugccu auggugcagg gcaagugaug uuacgguggg gagucuuagc aaaaucaguu      900

aaaaauauua uguuaggaca ugcuagugug caagcagaaa uggaacaagu uguugagguu      960

uaugaauaug cccaaaaauu ggguggugaa gcaggauucu accauauauu gaacaaccca     1020

aaagcaucau uauuaucuuu gacucaauuu ccucacuucu ccaguguagu auuaggcaau     1080

gcugcuggcc uaggcauaau gggagaguac agagguacac cgaggaauca agaucuauau     1140

gaugcagcaa aggcauaugc ugaacaacuc aaagaaaaug gugugauuaa cuacagugua     1200

cuagacuuga cagcagaaga acuagaggcu aucaaacauc agcuuaaucc aaaagauaau     1260

gauguagagc uuugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10312
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10312
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cucaacgaca cccugaacaa ggaccagcug cucuccagcu ccaaguacac cauccagcgc      180

agcaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcug      240

ugcgggaugc ugcucaucac cgaggacgcc aaccacaagu ucaccggccu gaucgggaug      300

cuguacgcga ugagccggcu cggccgcgag gacacgauca agauccugcg ggacgccggg      360

uaccacguga aggccaacgg cguggacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccucgcc ucccugacga ccgagaucca gaucaacauc      480

gagaucgaga gccggaaguc cuacaagaag augcugaagg agauggggga gguggccccg      540

gaguaccgcc acgacagccc cgacugcggc augaucaucc ucugcaucgc ggcccugguc      600

aucaccaagc uggccgccgg ggaccggucc ggccucaccg cggugauccg ccgggccaac      660

aacgugcuga agaacgagau gaagcgcuac aaggggcugc uccccaagga caucgccaac      720

agcuucuacg aggucuucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccagu ccagcacgcg gggcgggucc cgcgucgagg gcaucuucgc cgggcuguuc      840

augaacgcgu acggcgccgg ccaggugaug cugcgguggg gcgugcucgc caagagcguc      900

aagaacauca ugcuggggca cgccuccgug caggccgaga uggagcaggu cguggaggug      960

uacgaguacg cgcagaagcu cgggggcgag gccggguucu accacauccu gaacaacccg     1020

aaggccagcc ugcugucccu cacccaguuc ccccacuuca gcagcguggu ccugggcaac     1080

gccgccggcc uggggaucau gggcgaguac cgcgggacgc cccggaacca ggaccucuac     1140

gacgcggcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacuccgug     1200

cuggaccuca ccgccgagga gcuggaggcg aucaagcacc agcugaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10313
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10313
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccucuc caaggucaag      120

cucaacgaca cccucaacaa ggaccagcuc cucuccuccu ccaaguacac cauccagcgc      180

uccaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcuc      240

ugcggcaugc uccucaucac cgaggacgcc aaccacaagu ucaccggccu caucggcaug      300

cucuacgcca ugucccgccu cggccgcgag gacaccauca agauccuccg cgacgccggc      360

uaccacguca aggccaacgg cgucgacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgagguccu cacccucgcc ucccucacca ccgagaucca gaucaacauc      480

gagaucgagu cccgcaaguc cuacaagaag augcucaagg agaugggcga ggucgccccc      540

gaguaccgcc acgacucccc cgacugcggc augaucaucc ucugcaucgc cgcccucguc      600

aucaccaagc ucgccgccgg cgaccgcucc ggccucaccg ccgucauccg ccgcgccaac      660

aacguccuca agaacgagau gaagcgcuac aagggccucc uccccaagga caucgccaac      720

uccuucuacg aggucuucga gaagcacccc cacuucaucg acgucuucgu ccacuucggc      780

aucgcccagu ccuccacccg cggcggcucc cgcgucgagg gcaucuucgc cggccucuuc      840

augaacgccu acggcgccgg ccaggucaug cuccgcuggg gcguccucgc caaguccguc      900

aagaacauca ugcucggcca cgccuccguc caggccgaga uggagcaggu cgucgagguc      960

uacgaguacg cccagaagcu cggcggcgag gccggcuucu accacauccu caacaacccc     1020

aaggccuccc uccucucccu cacccaguuc ccccacuucu ccuccgucgu ccucggcaac     1080

gccgccggcc ucggcaucau gggcgaguac cgcggcaccc cccgcaacca ggaccucuac     1140

gacgccgcca aggccuacgc cgagcagcuc aaggagaacg gcgucaucaa cuacuccguc     1200

cucgaccuca ccgccgagga gcucgaggcc aucaagcacc agcucaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10314
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10314
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccuuaauaa ggaucagcug uuguccucuu caaaauacac aauccaaaga      180

aguacuggcg acagcauuga uacgcccaac uaugacgucc agaagcacau aaauaaauua      240

ugcgggaugc ugcuaaucac cgaggaugcu aaccauaagu ucacaggacu cauugguaug      300

cuguacgcaa uguccaggcu uggccgggaa gacacuauca agauucugcg cgaugccggg      360

uaucacguua aagcgaaugg aguggacgua accacacauc gacaggauau caacggcaag      420

gagaugaaau uugaaguguu gacccucgcu ucucugacua cagagauaca gaucaauauu      480

gaaaucgagu cgcguaaguc auacaaaaag augcugaagg agauggguga agucgccccu      540

gaguauagac acgacagccc agauuguggg augauuaucc ucugcauagc agccuuagug      600

auuaccaaac uggcugcagg agacaggagu ggccuuacgg ccguuauccg gcgcgcuaac      660

aauguguuga agaacgaaau gaaaagauac aagggccugc uaccgaaaga uauugccaau      720

uccuucuaug aggucuuuga gaagcauccc cacuucaucg acguguuugu acacuucggg      780

aucgcgcaau cuagcacuag gggagguucc cggguugaag gcauuuuugc aggacucuuc      840

augaacgccu acggggcugg ccaggugaug cugcgcuggg guguccuugc caaaucagug      900

aagaauauaa ugcuggggca ugcaagugug caggcugaga uggaacaggu cguugaggug      960

uacgaauaug cccaaaaguu gggaggcgag gcgggcuuuu accacauccu caacaauccu     1020

aaagccagcc uguuaucucu gacccaguuc ccacauuuuu ccucaguagu gcucgggaac     1080

gcagcuggac uugguauuau gggcgaguau cgagggacac ccagaaacca ggaccuguac     1140

gaugccgcua aggccuaugc agaacaguug aaagagaaug gagucaucaa cuacagcgug     1200

cuagaccuga cugccgagga acucgaagcu auaaagcacc aacugaaucc uaaagauaac     1260

gacguugagc uuugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10315
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10315
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cugaacgaca cccugaacaa ggaccagcug cugagcagca gcaaguacac cauccagaga      180

agcaccggcg acagcaucga cacccccaac uacgacgugc agaagcacau caacaagcug      240

ugcggcaugc ugcugaucac cgaggacgcc aaccacaagu ucaccggccu gaucggcaug      300

cuguacgcca ugagcagacu gggcagagag gacaccauca agauccugag agacgccggc      360

uaccacguga aggccaacgg cguggacgug accacccaca gacaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccuggcc agccugacca ccgagaucca gaucaacauc      480

gagaucgaga gcagaaagag cuacaagaag augcugaagg agaugggcga gguggccccc      540

gaguacagac acgacagccc cgacugcggc augaucaucc ugugcaucgc cgcccuggug      600

aucaccaagc uggccgccgg cgacagaagc ggccugaccg ccgugaucag aagagccaac      660

aacgugcuga agaacgagau gaagagauac aagggccugc ugcccaagga caucgccaac      720

agcuucuacg agguguucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccaga gcagcaccag aggcggcagc agaguggagg gcaucuucgc cggccuguuc      840

augaacgccu acggcgccgg ccaggugaug cugagauggg gcgugcuggc caagagcgug      900

aagaacauca ugcugggcca cgccagcgug caggccgaga uggagcaggu gguggaggug      960

uacgaguacg cccagaagcu gggcggcgag gccggcuucu accacauccu gaacaacccc     1020

aaggccagcc ugcugagccu gacccaguuc ccccacuuca gcagcguggu gcugggcaac     1080

gccgccggcc ugggcaucau gggcgaguac agaggcaccc ccagaaacca ggaccuguac     1140

gacgccgcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacagcgug     1200

cuggaccuga ccgccgagga gcuggaggcc aucaagcacc agcugaaccc caaggacaac     1260

gacguggagc ugugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10316
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10316
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccugaauaa ggaucagcuu cuguccucua gcaaauacac aauccaaaga      180

uccacgggcg acucuauuga uacccccaac uaugacgucc agaagcacau caauaaacuc      240

ugcgggaugc ugcuuauuac agaggaugcu aaccauaagu ucaccggacu gaucggcaug      300

cucuacgcca ugagccggcu ggggcgcgaa gacacaauua agauccugag agaugcggga      360

uaucacguua aagcuaaugg cguggacgug accacacauc ggcaggauau caacgggaag      420

gagaugaaau uugaaguccu cacccuggcc ucccuuacga ccgagauuca gaucaauauu      480

gaaaucgagu cucgcaagag cuacaaaaag augcugaagg agaugggaga aguggccccu      540

gaguauagac acgacucccc ggauuguggc augauuaucc ucugcauugc ugcccugguu      600

aucacaaaac uugcugccgg cgaccggagc gggcugaccg cggugauccg cagagccaac      660

aauguccuca agaacgaaau gaaacgguac aagggacugc ugcccaaaga uauugcuaau      720

ucuuucuaug agguguuuga gaagcauccu cacuucaucg acguuuuugu gcacuucggc      780

auugcccaau ccagcacacg cgggggaucu agagucgaag gcaucuuugc uggacucuuc      840

augaacgccu acggggcggg ccaggugaug cugcgguggg gcgugcuugc caaauccguc      900

aagaauauua ugcuggggca ugcuagcguu caggccgaga uggaacaggu gguggagguc      960

uacgaauaug cucaaaagcu cggaggcgag gccggguuuu accacauccu gaacaauccc     1020

aaagccucuc uucugucccu cacccaguuc ccucauuuua gcuccguggu ucugggaaac     1080

gcugcgggcc uggggaucau gggagaguau cgcggcacgc ccagaaacca ggaccucuac     1140

gaugccgcua aggccuaugc cgaacagcug aaagagaaug gcgugauuaa cuacucuguc     1200

cuugaccuga cagcugagga acucgaagcc aucaagcacc aacugaaucc uaaagauaac     1260

gacguggagc uuugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10317
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10317
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacuaag caaagucaaa      120

uuaaacgaca cauuaaacaa agaccaacuc uuaucaucau caaaauacac aauacaaaga      180

agcaccggag acaguaucga cacaccaaac uaugacgucc aaaaacauau aaauaaauua      240

ugcggcaugc ucuuaaucac agaagacgcc aaccauaaau uuacaggauu aauaggaaug      300

uuauaugcaa ugucacgacu agguagagaa gacacaauaa aaauacuaag agacgcaggc      360

uaucacguaa aagcaaaugg aguagacgua accacacaca gacaagacau aaauggaaaa      420

gaaaugaaau uugaaguauu aacacuagca ucacuaacaa cagaaauaca aaucaacaua      480

gaaauagaau caagaaaaag cuacaaaaaa auguuaaaag aaaugggaga agucgcacca      540

gaauauagac augauucacc agacugcgga augauaauac uaugcauagc agcccuagua      600

auuacaaaac uagcagcagg agacagaagc ggauuaacag caguaauaag aagagcaaac      660

aacguacuaa aaaacgaaau gaaaagauau aaaggauuau uaccaaaaga cauagcaaac      720

ucauucuaug aaguauucga aaaacacccc cacuuuauag acgucuucgu acacuucgga      780

auagcccaau cauccacaag aggaggauca agagucgaag gaauauucgc aggauuauuc      840

augaacgcau auggcgcagg acaaguaaug cuaagauggg gaguacuagc aaaauccguc      900

aaaaacauaa ugcuaggaca cgcaucaguu caagcagaaa uggaacaagu aguagaagua      960

uacgaauacg cccaaaaacu aggaggagaa gcaggauucu accacauacu aaauaaucca     1020

aaagcaucac uacuaagccu aacccaauuu ccccacuucu caaguguagu auuaggaaau     1080

gcagcuggac uaggaauaau gggagaauac agaggaacac caagaaacca agacuuauac     1140

gacgcagcaa aagcauacgc agagcaacuu aaagaaaacg gaguaauaaa cuauagcgua     1200

cuagacuuaa cagcagaaga acuggaagca auaaaacauc aauuaaaccc gaaagacaau     1260

gacguagaau uauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10318
<211>  1487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10318
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacucuc gaaaguaaaa      120

cucaacgaca cccucaacaa agaccaacuc cuuuccagcu ccaaauacac cauccaacga      180

uccaccggag acuccaucga cacgcccaac uacgacgucc agaaacacau caacaagcuc      240

ugcggaaugc uacuaaucac cgaggacgcc aaccacaaau ucacaggacu uauagggaug      300

cucuacgcca ugucccgccu cggacgcgaa gacacaauaa aaauccuacg agacgccggc      360

uaccacguaa aggcaaacgg cgucgacguc accacacaca gacaagacau caacggaaag      420

gaaaugaaau ucgaaguccu cacccucgcc agccuaacca ccgagaucca aaucaacauc      480

gaaaucgaau cacgcaaauc cuacaagaaa augcucaaag aaaugggaga agucgccccc      540

gaauaccguc acgacucgcc cgacugcggc augauaaucc uaugcaucgc cgcacucguc      600

auaaccaaac ucgccgccgg ugaccgauca ggacugacag cagucauccg ccgagcaaac      660

aacgugcuca aaaacgaaau gaaacgcuac aaaggccuac uccccaaaga caucgccaac      720

uccuucuacg aagucuucga aaaacaccca cacuucaucg acgucuucgu ccacuucggc      780

aucgcacaau caucaaccag aggcggcagc cgcguugaag gcaucuucgc aggacucuuu      840

augaacgccu acggcgccgg ccaagucaug cuccgcuggg gcguccuggc aaaaagcguc      900

aaaaacauca ugcuaggcca cgcuagcguc caagccgaaa uggaacaagu cgucgaaguu      960

uacgaguacg cacaaaaacu cggcggcgaa gcaggcuucu accacauccu aaacaacccc     1020

aaagccuccc ugcuaucacu cacccaauuc ccccacuucu ccagcgucgu ccucggcaac     1080

gccgcaggac uaggcaucau gggagaauac cgcgggacac cgcgcaacca agaccucuac     1140

gacgccgcca aagccuacgc cgaacaacuc aaagaaaacg gcgucauaaa cuacucaguc     1200

cucgaccuca ccgccgaaga acucgaagcc aucaaacacc aacucaaccc aaaagacaac     1260

gacgucgaau uauaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu     1320

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc     1440

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1487


<210>  10319
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10319
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcucuuag caaagucaag uugaaugaua cacucaacaa agaucaacuu      120

cugucaucca gcaaauacac cauccaacgg agcacaggag auaguauuga uacuccuaau      180

uaugaugugc agaaacacau caauaaguua uguggcaugu uauuaaucac agaagaugcu      240

aaucauaaau ucacuggguu aauagguaug uuauaugcga ugucuagguu aggaagagaa      300

gacaccauaa aaauacucag agaugcggga uaucauguaa aagcaaaugg aguagaugua      360

acaacacauc gucaagacau uaauggaaaa gaaaugaaau uugaaguguu aacauuggca      420

agcuuaacaa cugaaauuca aaucaacauu gagauagaau cuagaaaauc cuacaaaaaa      480

augcuaaaag aaaugggaga gguagcucca gaauacaggc augacucucc ugauuguggg      540

augauaauau uauguauagc agcauuagua auaacuaaau uagcagcagg ggacagaucu      600

ggucuuacag ccgugauuag gagagcuaau aauguccuaa aaaaugaaau gaaacguuac      660

aaaggcuuac uacccaagga cauagccaac agcuucuaug aaguguuuga aaaacauccc      720

cacuuuauag auguuuuugu ucauuuuggu auagcacaau cuucuaccag agguggcagu      780

agaguugaag ggauuuuugc aggauuguuu augaaugccu auggugcagg gcaagugaug      840

uuacgguggg gagucuuagc aaaaucaguu aaaaauauua uguuaggaca ugcuagugug      900

caagcagaaa uggaacaagu uguugagguu uaugaauaug cccaaaaauu ggguggugaa      960

gcaggauucu accauauauu gaacaaccca aaagcaucau uauuaucuuu gacucaauuu     1020

ccucacuucu ccaguguagu auuaggcaau gcugcuggcc uaggcauaau gggagaguac     1080

agagguacac cgaggaauca agaucuauau gaugcagcaa aggcauaugc ugaacaacuc     1140

aaagaaaaug gugugauuaa cuacagugua cuagacuuga cagcagaaga acuagaggcu     1200

aucaaacauc agcuuaaucc aaaagauaau gauguagagc uuugaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10320
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10320
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cucaacgaca cccugaacaa ggaccagcug      120

cucuccagcu ccaaguacac cauccagcgc agcaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcug ugcgggaugc ugcucaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucgggaug cuguacgcga ugagccggcu cggccgcgag      300

gacacgauca agauccugcg ggacgccggg uaccacguga aggccaacgg cguggacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgaggugcu gacccucgcc      420

ucccugacga ccgagaucca gaucaacauc gagaucgaga gccggaaguc cuacaagaag      480

augcugaagg agauggggga gguggccccg gaguaccgcc acgacagccc cgacugcggc      540

augaucaucc ucugcaucgc ggcccugguc aucaccaagc uggccgccgg ggaccggucc      600

ggccucaccg cggugauccg ccgggccaac aacgugcuga agaacgagau gaagcgcuac      660

aaggggcugc uccccaagga caucgccaac agcuucuacg aggucuucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccagu ccagcacgcg gggcgggucc      780

cgcgucgagg gcaucuucgc cgggcuguuc augaacgcgu acggcgccgg ccaggugaug      840

cugcgguggg gcgugcucgc caagagcguc aagaacauca ugcuggggca cgccuccgug      900

caggccgaga uggagcaggu cguggaggug uacgaguacg cgcagaagcu cgggggcgag      960

gccggguucu accacauccu gaacaacccg aaggccagcc ugcugucccu cacccaguuc     1020

ccccacuuca gcagcguggu ccugggcaac gccgccggcc uggggaucau gggcgaguac     1080

cgcgggacgc cccggaacca ggaccucuac gacgcggcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacuccgug cuggaccuca ccgccgagga gcuggaggcg     1200

aucaagcacc agcugaaccc caaggacaac gacgucgagc ucugaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10321
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10321
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccucuc caaggucaag cucaacgaca cccucaacaa ggaccagcuc      120

cucuccuccu ccaaguacac cauccagcgc uccaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcuc ugcggcaugc uccucaucac cgaggacgcc      240

aaccacaagu ucaccggccu caucggcaug cucuacgcca ugucccgccu cggccgcgag      300

gacaccauca agauccuccg cgacgccggc uaccacguca aggccaacgg cgucgacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgagguccu cacccucgcc      420

ucccucacca ccgagaucca gaucaacauc gagaucgagu cccgcaaguc cuacaagaag      480

augcucaagg agaugggcga ggucgccccc gaguaccgcc acgacucccc cgacugcggc      540

augaucaucc ucugcaucgc cgcccucguc aucaccaagc ucgccgccgg cgaccgcucc      600

ggccucaccg ccgucauccg ccgcgccaac aacguccuca agaacgagau gaagcgcuac      660

aagggccucc uccccaagga caucgccaac uccuucuacg aggucuucga gaagcacccc      720

cacuucaucg acgucuucgu ccacuucggc aucgcccagu ccuccacccg cggcggcucc      780

cgcgucgagg gcaucuucgc cggccucuuc augaacgccu acggcgccgg ccaggucaug      840

cuccgcuggg gcguccucgc caaguccguc aagaacauca ugcucggcca cgccuccguc      900

caggccgaga uggagcaggu cgucgagguc uacgaguacg cccagaagcu cggcggcgag      960

gccggcuucu accacauccu caacaacccc aaggccuccc uccucucccu cacccaguuc     1020

ccccacuucu ccuccgucgu ccucggcaac gccgccggcc ucggcaucau gggcgaguac     1080

cgcggcaccc cccgcaacca ggaccucuac gacgccgcca aggccuacgc cgagcagcuc     1140

aaggagaacg gcgucaucaa cuacuccguc cucgaccuca ccgccgagga gcucgaggcc     1200

aucaagcacc agcucaaccc caaggacaac gacgucgagc ucugaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10322
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10322
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccuuaauaa ggaucagcug      120

uuguccucuu caaaauacac aauccaaaga aguacuggcg acagcauuga uacgcccaac      180

uaugacgucc agaagcacau aaauaaauua ugcgggaugc ugcuaaucac cgaggaugcu      240

aaccauaagu ucacaggacu cauugguaug cuguacgcaa uguccaggcu uggccgggaa      300

gacacuauca agauucugcg cgaugccggg uaucacguua aagcgaaugg aguggacgua      360

accacacauc gacaggauau caacggcaag gagaugaaau uugaaguguu gacccucgcu      420

ucucugacua cagagauaca gaucaauauu gaaaucgagu cgcguaaguc auacaaaaag      480

augcugaagg agauggguga agucgccccu gaguauagac acgacagccc agauuguggg      540

augauuaucc ucugcauagc agccuuagug auuaccaaac uggcugcagg agacaggagu      600

ggccuuacgg ccguuauccg gcgcgcuaac aauguguuga agaacgaaau gaaaagauac      660

aagggccugc uaccgaaaga uauugccaau uccuucuaug aggucuuuga gaagcauccc      720

cacuucaucg acguguuugu acacuucggg aucgcgcaau cuagcacuag gggagguucc      780

cggguugaag gcauuuuugc aggacucuuc augaacgccu acggggcugg ccaggugaug      840

cugcgcuggg guguccuugc caaaucagug aagaauauaa ugcuggggca ugcaagugug      900

caggcugaga uggaacaggu cguugaggug uacgaauaug cccaaaaguu gggaggcgag      960

gcgggcuuuu accacauccu caacaauccu aaagccagcc uguuaucucu gacccaguuc     1020

ccacauuuuu ccucaguagu gcucgggaac gcagcuggac uugguauuau gggcgaguau     1080

cgagggacac ccagaaacca ggaccuguac gaugccgcua aggccuaugc agaacaguug     1140

aaagagaaug gagucaucaa cuacagcgug cuagaccuga cugccgagga acucgaagcu     1200

auaaagcacc aacugaaucc uaaagauaac gacguugagc uuugaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10323
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10323
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cugaacgaca cccugaacaa ggaccagcug      120

cugagcagca gcaaguacac cauccagaga agcaccggcg acagcaucga cacccccaac      180

uacgacgugc agaagcacau caacaagcug ugcggcaugc ugcugaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucggcaug cuguacgcca ugagcagacu gggcagagag      300

gacaccauca agauccugag agacgccggc uaccacguga aggccaacgg cguggacgug      360

accacccaca gacaggacau caacggcaag gagaugaagu ucgaggugcu gacccuggcc      420

agccugacca ccgagaucca gaucaacauc gagaucgaga gcagaaagag cuacaagaag      480

augcugaagg agaugggcga gguggccccc gaguacagac acgacagccc cgacugcggc      540

augaucaucc ugugcaucgc cgcccuggug aucaccaagc uggccgccgg cgacagaagc      600

ggccugaccg ccgugaucag aagagccaac aacgugcuga agaacgagau gaagagauac      660

aagggccugc ugcccaagga caucgccaac agcuucuacg agguguucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccaga gcagcaccag aggcggcagc      780

agaguggagg gcaucuucgc cggccuguuc augaacgccu acggcgccgg ccaggugaug      840

cugagauggg gcgugcuggc caagagcgug aagaacauca ugcugggcca cgccagcgug      900

caggccgaga uggagcaggu gguggaggug uacgaguacg cccagaagcu gggcggcgag      960

gccggcuucu accacauccu gaacaacccc aaggccagcc ugcugagccu gacccaguuc     1020

ccccacuuca gcagcguggu gcugggcaac gccgccggcc ugggcaucau gggcgaguac     1080

agaggcaccc ccagaaacca ggaccuguac gacgccgcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacagcgug cuggaccuga ccgccgagga gcuggaggcc     1200

aucaagcacc agcugaaccc caaggacaac gacguggagc ugugaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10324
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10324
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccugaauaa ggaucagcuu      120

cuguccucua gcaaauacac aauccaaaga uccacgggcg acucuauuga uacccccaac      180

uaugacgucc agaagcacau caauaaacuc ugcgggaugc ugcuuauuac agaggaugcu      240

aaccauaagu ucaccggacu gaucggcaug cucuacgcca ugagccggcu ggggcgcgaa      300

gacacaauua agauccugag agaugcggga uaucacguua aagcuaaugg cguggacgug      360

accacacauc ggcaggauau caacgggaag gagaugaaau uugaaguccu cacccuggcc      420

ucccuuacga ccgagauuca gaucaauauu gaaaucgagu cucgcaagag cuacaaaaag      480

augcugaagg agaugggaga aguggccccu gaguauagac acgacucccc ggauuguggc      540

augauuaucc ucugcauugc ugcccugguu aucacaaaac uugcugccgg cgaccggagc      600

gggcugaccg cggugauccg cagagccaac aauguccuca agaacgaaau gaaacgguac      660

aagggacugc ugcccaaaga uauugcuaau ucuuucuaug agguguuuga gaagcauccu      720

cacuucaucg acguuuuugu gcacuucggc auugcccaau ccagcacacg cgggggaucu      780

agagucgaag gcaucuuugc uggacucuuc augaacgccu acggggcggg ccaggugaug      840

cugcgguggg gcgugcuugc caaauccguc aagaauauua ugcuggggca ugcuagcguu      900

caggccgaga uggaacaggu gguggagguc uacgaauaug cucaaaagcu cggaggcgag      960

gccggguuuu accacauccu gaacaauccc aaagccucuc uucugucccu cacccaguuc     1020

ccucauuuua gcuccguggu ucugggaaac gcugcgggcc uggggaucau gggagaguau     1080

cgcggcacgc ccagaaacca ggaccucuac gaugccgcua aggccuaugc cgaacagcug     1140

aaagagaaug gcgugauuaa cuacucuguc cuugaccuga cagcugagga acucgaagcc     1200

aucaagcacc aacugaaucc uaaagauaac gacguggagc uuugaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10325
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10325
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacuaag caaagucaaa uuaaacgaca cauuaaacaa agaccaacuc      120

uuaucaucau caaaauacac aauacaaaga agcaccggag acaguaucga cacaccaaac      180

uaugacgucc aaaaacauau aaauaaauua ugcggcaugc ucuuaaucac agaagacgcc      240

aaccauaaau uuacaggauu aauaggaaug uuauaugcaa ugucacgacu agguagagaa      300

gacacaauaa aaauacuaag agacgcaggc uaucacguaa aagcaaaugg aguagacgua      360

accacacaca gacaagacau aaauggaaaa gaaaugaaau uugaaguauu aacacuagca      420

ucacuaacaa cagaaauaca aaucaacaua gaaauagaau caagaaaaag cuacaaaaaa      480

auguuaaaag aaaugggaga agucgcacca gaauauagac augauucacc agacugcgga      540

augauaauac uaugcauagc agcccuagua auuacaaaac uagcagcagg agacagaagc      600

ggauuaacag caguaauaag aagagcaaac aacguacuaa aaaacgaaau gaaaagauau      660

aaaggauuau uaccaaaaga cauagcaaac ucauucuaug aaguauucga aaaacacccc      720

cacuuuauag acgucuucgu acacuucgga auagcccaau cauccacaag aggaggauca      780

agagucgaag gaauauucgc aggauuauuc augaacgcau auggcgcagg acaaguaaug      840

cuaagauggg gaguacuagc aaaauccguc aaaaacauaa ugcuaggaca cgcaucaguu      900

caagcagaaa uggaacaagu aguagaagua uacgaauacg cccaaaaacu aggaggagaa      960

gcaggauucu accacauacu aaauaaucca aaagcaucac uacuaagccu aacccaauuu     1020

ccccacuucu caaguguagu auuaggaaau gcagcuggac uaggaauaau gggagaauac     1080

agaggaacac caagaaacca agacuuauac gacgcagcaa aagcauacgc agagcaacuu     1140

aaagaaaacg gaguaauaaa cuauagcgua cuagacuuaa cagcagaaga acuggaagca     1200

auaaaacauc aauuaaaccc gaaagacaau gacguagaau uauaaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10326
<211>  1457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10326
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacucuc gaaaguaaaa cucaacgaca cccucaacaa agaccaacuc      120

cuuuccagcu ccaaauacac cauccaacga uccaccggag acuccaucga cacgcccaac      180

uacgacgucc agaaacacau caacaagcuc ugcggaaugc uacuaaucac cgaggacgcc      240

aaccacaaau ucacaggacu uauagggaug cucuacgcca ugucccgccu cggacgcgaa      300

gacacaauaa aaauccuacg agacgccggc uaccacguaa aggcaaacgg cgucgacguc      360

accacacaca gacaagacau caacggaaag gaaaugaaau ucgaaguccu cacccucgcc      420

agccuaacca ccgagaucca aaucaacauc gaaaucgaau cacgcaaauc cuacaagaaa      480

augcucaaag aaaugggaga agucgccccc gaauaccguc acgacucgcc cgacugcggc      540

augauaaucc uaugcaucgc cgcacucguc auaaccaaac ucgccgccgg ugaccgauca      600

ggacugacag cagucauccg ccgagcaaac aacgugcuca aaaacgaaau gaaacgcuac      660

aaaggccuac uccccaaaga caucgccaac uccuucuacg aagucuucga aaaacaccca      720

cacuucaucg acgucuucgu ccacuucggc aucgcacaau caucaaccag aggcggcagc      780

cgcguugaag gcaucuucgc aggacucuuu augaacgccu acggcgccgg ccaagucaug      840

cuccgcuggg gcguccuggc aaaaagcguc aaaaacauca ugcuaggcca cgcuagcguc      900

caagccgaaa uggaacaagu cgucgaaguu uacgaguacg cacaaaaacu cggcggcgaa      960

gcaggcuucu accacauccu aaacaacccc aaagccuccc ugcuaucacu cacccaauuc     1020

ccccacuucu ccagcgucgu ccucggcaac gccgcaggac uaggcaucau gggagaauac     1080

cgcgggacac cgcgcaacca agaccucuac gacgccgcca aagccuacgc cgaacaacuc     1140

aaagaaaacg gcgucauaaa cuacucaguc cucgaccuca ccgccgaaga acucgaagcc     1200

aucaaacacc aacucaaccc aaaagacaac gacgucgaau uauaaggacu aguguccacc     1260

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu     1320

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1440

ucagagccac cagaauu                                                    1457


<210>  10327
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10327
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcuc uuagcaaagu caaguugaau gauacacuca acaaagauca acuucuguca      180

uccagcaaau acaccaucca acggagcaca ggagauagua uugauacucc uaauuaugau      240

gugcagaaac acaucaauaa guuauguggc auguuauuaa ucacagaaga ugcuaaucau      300

aaauucacug gguuaauagg uauguuauau gcgaugucua gguuaggaag agaagacacc      360

auaaaaauac ucagagaugc gggauaucau guaaaagcaa auggaguaga uguaacaaca      420

caucgucaag acauuaaugg aaaagaaaug aaauuugaag uguuaacauu ggcaagcuua      480

acaacugaaa uucaaaucaa cauugagaua gaaucuagaa aauccuacaa aaaaaugcua      540

aaagaaaugg gagagguagc uccagaauac aggcaugacu cuccugauug ugggaugaua      600

auauuaugua uagcagcauu aguaauaacu aaauuagcag caggggacag aucuggucuu      660

acagccguga uuaggagagc uaauaauguc cuaaaaaaug aaaugaaacg uuacaaaggc      720

uuacuaccca aggacauagc caacagcuuc uaugaagugu uugaaaaaca uccccacuuu      780

auagauguuu uuguucauuu ugguauagca caaucuucua ccagaggugg caguagaguu      840

gaagggauuu uugcaggauu guuuaugaau gccuauggug cagggcaagu gauguuacgg      900

uggggagucu uagcaaaauc aguuaaaaau auuauguuag gacaugcuag ugugcaagca      960

gaaauggaac aaguuguuga gguuuaugaa uaugcccaaa aauugggugg ugaagcagga     1020

uucuaccaua uauugaacaa cccaaaagca ucauuauuau cuuugacuca auuuccucac     1080

uucuccagug uaguauuagg caaugcugcu ggccuaggca uaaugggaga guacagaggu     1140

acaccgagga aucaagaucu auaugaugca gcaaaggcau augcugaaca acucaaagaa     1200

aaugguguga uuaacuacag uguacuagac uugacagcag aagaacuaga ggcuaucaaa     1260

caucagcuua auccaaaaga uaaugaugua gagcuuugag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10328
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10328
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcucaac gacacccuga acaaggacca gcugcucucc      180

agcuccaagu acaccaucca gcgcagcacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcugugcggg augcugcuca ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg gaugcuguac gcgaugagcc ggcucggccg cgaggacacg      360

aucaagaucc ugcgggacgc cggguaccac gugaaggcca acggcgugga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg ugcugacccu cgccucccug      480

acgaccgaga uccagaucaa caucgagauc gagagccgga aguccuacaa gaagaugcug      540

aaggagaugg gggagguggc cccggaguac cgccacgaca gccccgacug cggcaugauc      600

auccucugca ucgcggcccu ggucaucacc aagcuggccg ccggggaccg guccggccuc      660

accgcgguga uccgccgggc caacaacgug cugaagaacg agaugaagcg cuacaagggg      720

cugcucccca aggacaucgc caacagcuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc caguccagca cgcggggcgg gucccgcguc      840

gagggcaucu ucgccgggcu guucaugaac gcguacggcg ccggccaggu gaugcugcgg      900

uggggcgugc ucgccaagag cgucaagaac aucaugcugg ggcacgccuc cgugcaggcc      960

gagauggagc aggucgugga gguguacgag uacgcgcaga agcucggggg cgaggccggg     1020

uucuaccaca uccugaacaa cccgaaggcc agccugcugu cccucaccca guucccccac     1080

uucagcagcg ugguccuggg caacgccgcc ggccugggga ucaugggcga guaccgcggg     1140

acgccccgga accaggaccu cuacgacgcg gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacuc cgugcuggac cucaccgccg aggagcugga ggcgaucaag     1260

caccagcuga accccaagga caacgacguc gagcucugag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10329
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10329
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ucuccaaggu caagcucaac gacacccuca acaaggacca gcuccucucc      180

uccuccaagu acaccaucca gcgcuccacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcucugcggc augcuccuca ucaccgagga cgccaaccac      300

aaguucaccg gccucaucgg caugcucuac gccauguccc gccucggccg cgaggacacc      360

aucaagaucc uccgcgacgc cggcuaccac gucaaggcca acggcgucga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg uccucacccu cgccucccuc      480

accaccgaga uccagaucaa caucgagauc gagucccgca aguccuacaa gaagaugcuc      540

aaggagaugg gcgaggucgc ccccgaguac cgccacgacu cccccgacug cggcaugauc      600

auccucugca ucgccgcccu cgucaucacc aagcucgccg ccggcgaccg cuccggccuc      660

accgccguca uccgccgcgc caacaacguc cucaagaacg agaugaagcg cuacaagggc      720

cuccucccca aggacaucgc caacuccuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgucu ucguccacuu cggcaucgcc caguccucca cccgcggcgg cucccgcguc      840

gagggcaucu ucgccggccu cuucaugaac gccuacggcg ccggccaggu caugcuccgc      900

uggggcgucc ucgccaaguc cgucaagaac aucaugcucg gccacgccuc cguccaggcc      960

gagauggagc aggucgucga ggucuacgag uacgcccaga agcucggcgg cgaggccggc     1020

uucuaccaca uccucaacaa ccccaaggcc ucccuccucu cccucaccca guucccccac     1080

uucuccuccg ucguccucgg caacgccgcc ggccucggca ucaugggcga guaccgcggc     1140

accccccgca accaggaccu cuacgacgcc gccaaggccu acgccgagca gcucaaggag     1200

aacggcguca ucaacuacuc cguccucgac cucaccgccg aggagcucga ggccaucaag     1260

caccagcuca accccaagga caacgacguc gagcucugag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10330
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10330
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuua auaaggauca gcuguugucc      180

ucuucaaaau acacaaucca aagaaguacu ggcgacagca uugauacgcc caacuaugac      240

guccagaagc acauaaauaa auuaugcggg augcugcuaa ucaccgagga ugcuaaccau      300

aaguucacag gacucauugg uaugcuguac gcaaugucca ggcuuggccg ggaagacacu      360

aucaagauuc ugcgcgaugc cggguaucac guuaaagcga auggagugga cguaaccaca      420

caucgacagg auaucaacgg caaggagaug aaauuugaag uguugacccu cgcuucucug      480

acuacagaga uacagaucaa uauugaaauc gagucgcgua agucauacaa aaagaugcug      540

aaggagaugg gugaagucgc cccugaguau agacacgaca gcccagauug ugggaugauu      600

auccucugca uagcagccuu agugauuacc aaacuggcug caggagacag gaguggccuu      660

acggccguua uccggcgcgc uaacaaugug uugaagaacg aaaugaaaag auacaagggc      720

cugcuaccga aagauauugc caauuccuuc uaugaggucu uugagaagca uccccacuuc      780

aucgacgugu uuguacacuu cgggaucgcg caaucuagca cuaggggagg uucccggguu      840

gaaggcauuu uugcaggacu cuucaugaac gccuacgggg cuggccaggu gaugcugcgc      900

uggggugucc uugccaaauc agugaagaau auaaugcugg ggcaugcaag ugugcaggcu      960

gagauggaac aggucguuga gguguacgaa uaugcccaaa aguugggagg cgaggcgggc     1020

uuuuaccaca uccucaacaa uccuaaagcc agccuguuau cucugaccca guucccacau     1080

uuuuccucag uagugcucgg gaacgcagcu ggacuuggua uuaugggcga guaucgaggg     1140

acacccagaa accaggaccu guacgaugcc gcuaaggccu augcagaaca guugaaagag     1200

aauggaguca ucaacuacag cgugcuagac cugacugccg aggaacucga agcuauaaag     1260

caccaacuga auccuaaaga uaacgacguu gagcuuugag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10331
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10331
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcugaac gacacccuga acaaggacca gcugcugagc      180

agcagcaagu acaccaucca gagaagcacc ggcgacagca ucgacacccc caacuacgac      240

gugcagaagc acaucaacaa gcugugcggc augcugcuga ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg caugcuguac gccaugagca gacugggcag agaggacacc      360

aucaagaucc ugagagacgc cggcuaccac gugaaggcca acggcgugga cgugaccacc      420

cacagacagg acaucaacgg caaggagaug aaguucgagg ugcugacccu ggccagccug      480

accaccgaga uccagaucaa caucgagauc gagagcagaa agagcuacaa gaagaugcug      540

aaggagaugg gcgagguggc ccccgaguac agacacgaca gccccgacug cggcaugauc      600

auccugugca ucgccgcccu ggugaucacc aagcuggccg ccggcgacag aagcggccug      660

accgccguga ucagaagagc caacaacgug cugaagaacg agaugaagag auacaagggc      720

cugcugccca aggacaucgc caacagcuuc uacgaggugu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc cagagcagca ccagaggcgg cagcagagug      840

gagggcaucu ucgccggccu guucaugaac gccuacggcg ccggccaggu gaugcugaga      900

uggggcgugc uggccaagag cgugaagaac aucaugcugg gccacgccag cgugcaggcc      960

gagauggagc agguggugga gguguacgag uacgcccaga agcugggcgg cgaggccggc     1020

uucuaccaca uccugaacaa ccccaaggcc agccugcuga gccugaccca guucccccac     1080

uucagcagcg uggugcuggg caacgccgcc ggccugggca ucaugggcga guacagaggc     1140

acccccagaa accaggaccu guacgacgcc gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacag cgugcuggac cugaccgccg aggagcugga ggccaucaag     1260

caccagcuga accccaagga caacgacgug gagcugugag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10332
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10332
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuga auaaggauca gcuucugucc      180

ucuagcaaau acacaaucca aagauccacg ggcgacucua uugauacccc caacuaugac      240

guccagaagc acaucaauaa acucugcggg augcugcuua uuacagagga ugcuaaccau      300

aaguucaccg gacugaucgg caugcucuac gccaugagcc ggcuggggcg cgaagacaca      360

auuaagaucc ugagagaugc gggauaucac guuaaagcua auggcgugga cgugaccaca      420

caucggcagg auaucaacgg gaaggagaug aaauuugaag uccucacccu ggccucccuu      480

acgaccgaga uucagaucaa uauugaaauc gagucucgca agagcuacaa aaagaugcug      540

aaggagaugg gagaaguggc cccugaguau agacacgacu ccccggauug uggcaugauu      600

auccucugca uugcugcccu gguuaucaca aaacuugcug ccggcgaccg gagcgggcug      660

accgcgguga uccgcagagc caacaauguc cucaagaacg aaaugaaacg guacaaggga      720

cugcugccca aagauauugc uaauucuuuc uaugaggugu uugagaagca uccucacuuc      780

aucgacguuu uugugcacuu cggcauugcc caauccagca cacgcggggg aucuagaguc      840

gaaggcaucu uugcuggacu cuucaugaac gccuacgggg cgggccaggu gaugcugcgg      900

uggggcgugc uugccaaauc cgucaagaau auuaugcugg ggcaugcuag cguucaggcc      960

gagauggaac agguggugga ggucuacgaa uaugcucaaa agcucggagg cgaggccggg     1020

uuuuaccaca uccugaacaa ucccaaagcc ucucuucugu cccucaccca guucccucau     1080

uuuagcuccg ugguucuggg aaacgcugcg ggccugggga ucaugggaga guaucgcggc     1140

acgcccagaa accaggaccu cuacgaugcc gcuaaggccu augccgaaca gcugaaagag     1200

aauggcguga uuaacuacuc uguccuugac cugacagcug aggaacucga agccaucaag     1260

caccaacuga auccuaaaga uaacgacgug gagcuuugag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10333
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10333
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac uaagcaaagu caaauuaaac gacacauuaa acaaagacca acucuuauca      180

ucaucaaaau acacaauaca aagaagcacc ggagacagua ucgacacacc aaacuaugac      240

guccaaaaac auauaaauaa auuaugcggc augcucuuaa ucacagaaga cgccaaccau      300

aaauuuacag gauuaauagg aauguuauau gcaaugucac gacuagguag agaagacaca      360

auaaaaauac uaagagacgc aggcuaucac guaaaagcaa auggaguaga cguaaccaca      420

cacagacaag acauaaaugg aaaagaaaug aaauuugaag uauuaacacu agcaucacua      480

acaacagaaa uacaaaucaa cauagaaaua gaaucaagaa aaagcuacaa aaaaauguua      540

aaagaaaugg gagaagucgc accagaauau agacaugauu caccagacug cggaaugaua      600

auacuaugca uagcagcccu aguaauuaca aaacuagcag caggagacag aagcggauua      660

acagcaguaa uaagaagagc aaacaacgua cuaaaaaacg aaaugaaaag auauaaagga      720

uuauuaccaa aagacauagc aaacucauuc uaugaaguau ucgaaaaaca cccccacuuu      780

auagacgucu ucguacacuu cggaauagcc caaucaucca caagaggagg aucaagaguc      840

gaaggaauau ucgcaggauu auucaugaac gcauauggcg caggacaagu aaugcuaaga      900

uggggaguac uagcaaaauc cgucaaaaac auaaugcuag gacacgcauc aguucaagca      960

gaaauggaac aaguaguaga aguauacgaa uacgcccaaa aacuaggagg agaagcagga     1020

uucuaccaca uacuaaauaa uccaaaagca ucacuacuaa gccuaaccca auuuccccac     1080

uucucaagug uaguauuagg aaaugcagcu ggacuaggaa uaaugggaga auacagagga     1140

acaccaagaa accaagacuu auacgacgca gcaaaagcau acgcagagca acuuaaagaa     1200

aacggaguaa uaaacuauag cguacuagac uuaacagcag aagaacugga agcaauaaaa     1260

caucaauuaa acccgaaaga caaugacgua gaauuauaag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10334
<211>  1511
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10334
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac ucucgaaagu aaaacucaac gacacccuca acaaagacca acuccuuucc      180

agcuccaaau acaccaucca acgauccacc ggagacucca ucgacacgcc caacuacgac      240

guccagaaac acaucaacaa gcucugcgga augcuacuaa ucaccgagga cgccaaccac      300

aaauucacag gacuuauagg gaugcucuac gccauguccc gccucggacg cgaagacaca      360

auaaaaaucc uacgagacgc cggcuaccac guaaaggcaa acggcgucga cgucaccaca      420

cacagacaag acaucaacgg aaaggaaaug aaauucgaag uccucacccu cgccagccua      480

accaccgaga uccaaaucaa caucgaaauc gaaucacgca aauccuacaa gaaaaugcuc      540

aaagaaaugg gagaagucgc ccccgaauac cgucacgacu cgcccgacug cggcaugaua      600

auccuaugca ucgccgcacu cgucauaacc aaacucgccg ccggugaccg aucaggacug      660

acagcaguca uccgccgagc aaacaacgug cucaaaaacg aaaugaaacg cuacaaaggc      720

cuacucccca aagacaucgc caacuccuuc uacgaagucu ucgaaaaaca cccacacuuc      780

aucgacgucu ucguccacuu cggcaucgca caaucaucaa ccagaggcgg cagccgcguu      840

gaaggcaucu ucgcaggacu cuuuaugaac gccuacggcg ccggccaagu caugcuccgc      900

uggggcgucc uggcaaaaag cgucaaaaac aucaugcuag gccacgcuag cguccaagcc      960

gaaauggaac aagucgucga aguuuacgag uacgcacaaa aacucggcgg cgaagcaggc     1020

uucuaccaca uccuaaacaa ccccaaagcc ucccugcuau cacucaccca auucccccac     1080

uucuccagcg ucguccucgg caacgccgca ggacuaggca ucaugggaga auaccgcggg     1140

acaccgcgca accaagaccu cuacgacgcc gccaaagccu acgccgaaca acucaaagaa     1200

aacggcguca uaaacuacuc aguccucgac cucaccgccg aagaacucga agccaucaaa     1260

caccaacuca acccaaaaga caacgacguc gaauuauaag gacuaguguc caccuguccc     1320

uccugggcug cuggauuguc ucguuuuccu gccaaauaaa caggaucagc gcuuuacaga     1380

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1500

ccaccagaau u                                                          1511


<210>  10335
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10335
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcucuua gcaaagucaa guugaaugau      120

acacucaaca aagaucaacu ucugucaucc agcaaauaca ccauccaacg gagcacagga      180

gauaguauug auacuccuaa uuaugaugug cagaaacaca ucaauaaguu auguggcaug      240

uuauuaauca cagaagaugc uaaucauaaa uucacugggu uaauagguau guuauaugcg      300

augucuaggu uaggaagaga agacaccaua aaaauacuca gagaugcggg auaucaugua      360

aaagcaaaug gaguagaugu aacaacacau cgucaagaca uuaauggaaa agaaaugaaa      420

uuugaagugu uaacauuggc aagcuuaaca acugaaauuc aaaucaacau ugagauagaa      480

ucuagaaaau ccuacaaaaa aaugcuaaaa gaaaugggag agguagcucc agaauacagg      540

caugacucuc cugauugugg gaugauaaua uuauguauag cagcauuagu aauaacuaaa      600

uuagcagcag gggacagauc uggucuuaca gccgugauua ggagagcuaa uaauguccua      660

aaaaaugaaa ugaaacguua caaaggcuua cuacccaagg acauagccaa cagcuucuau      720

gaaguguuug aaaaacaucc ccacuuuaua gauguuuuug uucauuuugg uauagcacaa      780

ucuucuacca gagguggcag uagaguugaa gggauuuuug caggauuguu uaugaaugcc      840

uauggugcag ggcaagugau guuacggugg ggagucuuag caaaaucagu uaaaaauauu      900

auguuaggac augcuagugu gcaagcagaa auggaacaag uuguugaggu uuaugaauau      960

gcccaaaaau ugggugguga agcaggauuc uaccauauau ugaacaaccc aaaagcauca     1020

uuauuaucuu ugacucaauu uccucacuuc uccaguguag uauuaggcaa ugcugcuggc     1080

cuaggcauaa ugggagagua cagagguaca ccgaggaauc aagaucuaua ugaugcagca     1140

aaggcauaug cugaacaacu caaagaaaau ggugugauua acuacagugu acuagacuug     1200

acagcagaag aacuagaggc uaucaaacau cagcuuaauc caaaagauaa ugauguagag     1260

cuuugaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10336
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10336
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcucaacgac      120

acccugaaca aggaccagcu gcucuccagc uccaaguaca ccauccagcg cagcaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu gugcgggaug      240

cugcucauca ccgaggacgc caaccacaag uucaccggcc ugaucgggau gcuguacgcg      300

augagccggc ucggccgcga ggacacgauc aagauccugc gggacgccgg guaccacgug      360

aaggccaacg gcguggacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccucgc cucccugacg accgagaucc agaucaacau cgagaucgag      480

agccggaagu ccuacaagaa gaugcugaag gagauggggg agguggcccc ggaguaccgc      540

cacgacagcc ccgacugcgg caugaucauc cucugcaucg cggcccuggu caucaccaag      600

cuggccgccg gggaccgguc cggccucacc gcggugaucc gccgggccaa caacgugcug      660

aagaacgaga ugaagcgcua caaggggcug cuccccaagg acaucgccaa cagcuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

uccagcacgc ggggcggguc ccgcgucgag ggcaucuucg ccgggcuguu caugaacgcg      840

uacggcgccg gccaggugau gcugcggugg ggcgugcucg ccaagagcgu caagaacauc      900

augcuggggc acgccuccgu gcaggccgag auggagcagg ucguggaggu guacgaguac      960

gcgcagaagc ucgggggcga ggccggguuc uaccacaucc ugaacaaccc gaaggccagc     1020

cugcuguccc ucacccaguu cccccacuuc agcagcgugg uccugggcaa cgccgccggc     1080

cuggggauca ugggcgagua ccgcgggacg ccccggaacc aggaccucua cgacgcggcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacuccgu gcuggaccuc     1200

accgccgagg agcuggaggc gaucaagcac cagcugaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10337
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10337
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccucu ccaaggucaa gcucaacgac      120

acccucaaca aggaccagcu ccucuccucc uccaaguaca ccauccagcg cuccaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu cugcggcaug      240

cuccucauca ccgaggacgc caaccacaag uucaccggcc ucaucggcau gcucuacgcc      300

augucccgcc ucggccgcga ggacaccauc aagauccucc gcgacgccgg cuaccacguc      360

aaggccaacg gcgucgacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggucc ucacccucgc cucccucacc accgagaucc agaucaacau cgagaucgag      480

ucccgcaagu ccuacaagaa gaugcucaag gagaugggcg aggucgcccc cgaguaccgc      540

cacgacuccc ccgacugcgg caugaucauc cucugcaucg ccgcccucgu caucaccaag      600

cucgccgccg gcgaccgcuc cggccucacc gccgucaucc gccgcgccaa caacguccuc      660

aagaacgaga ugaagcgcua caagggccuc cuccccaagg acaucgccaa cuccuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacgucuucg uccacuucgg caucgcccag      780

uccuccaccc gcggcggcuc ccgcgucgag ggcaucuucg ccggccucuu caugaacgcc      840

uacggcgccg gccaggucau gcuccgcugg ggcguccucg ccaaguccgu caagaacauc      900

augcucggcc acgccuccgu ccaggccgag auggagcagg ucgucgaggu cuacgaguac      960

gcccagaagc ucggcggcga ggccggcuuc uaccacaucc ucaacaaccc caaggccucc     1020

cuccucuccc ucacccaguu cccccacuuc uccuccgucg uccucggcaa cgccgccggc     1080

cucggcauca ugggcgagua ccgcggcacc ccccgcaacc aggaccucua cgacgccgcc     1140

aaggccuacg ccgagcagcu caaggagaac ggcgucauca acuacuccgu ccucgaccuc     1200

accgccgagg agcucgaggc caucaagcac cagcucaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10338
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10338
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccuuaaua aggaucagcu guuguccucu ucaaaauaca caauccaaag aaguacuggc      180

gacagcauug auacgcccaa cuaugacguc cagaagcaca uaaauaaauu augcgggaug      240

cugcuaauca ccgaggaugc uaaccauaag uucacaggac ucauugguau gcuguacgca      300

auguccaggc uuggccggga agacacuauc aagauucugc gcgaugccgg guaucacguu      360

aaagcgaaug gaguggacgu aaccacacau cgacaggaua ucaacggcaa ggagaugaaa      420

uuugaagugu ugacccucgc uucucugacu acagagauac agaucaauau ugaaaucgag      480

ucgcguaagu cauacaaaaa gaugcugaag gagaugggug aagucgcccc ugaguauaga      540

cacgacagcc cagauugugg gaugauuauc cucugcauag cagccuuagu gauuaccaaa      600

cuggcugcag gagacaggag uggccuuacg gccguuaucc ggcgcgcuaa caauguguug      660

aagaacgaaa ugaaaagaua caagggccug cuaccgaaag auauugccaa uuccuucuau      720

gaggucuuug agaagcaucc ccacuucauc gacguguuug uacacuucgg gaucgcgcaa      780

ucuagcacua ggggagguuc ccggguugaa ggcauuuuug caggacucuu caugaacgcc      840

uacggggcug gccaggugau gcugcgcugg gguguccuug ccaaaucagu gaagaauaua      900

augcuggggc augcaagugu gcaggcugag auggaacagg ucguugaggu guacgaauau      960

gcccaaaagu ugggaggcga ggcgggcuuu uaccacaucc ucaacaaucc uaaagccagc     1020

cuguuaucuc ugacccaguu cccacauuuu uccucaguag ugcucgggaa cgcagcugga     1080

cuugguauua ugggcgagua ucgagggaca cccagaaacc aggaccugua cgaugccgcu     1140

aaggccuaug cagaacaguu gaaagagaau ggagucauca acuacagcgu gcuagaccug     1200

acugccgagg aacucgaagc uauaaagcac caacugaauc cuaaagauaa cgacguugag     1260

cuuugaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10339
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10339
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcugaacgac      120

acccugaaca aggaccagcu gcugagcagc agcaaguaca ccauccagag aagcaccggc      180

gacagcaucg acacccccaa cuacgacgug cagaagcaca ucaacaagcu gugcggcaug      240

cugcugauca ccgaggacgc caaccacaag uucaccggcc ugaucggcau gcuguacgcc      300

augagcagac ugggcagaga ggacaccauc aagauccuga gagacgccgg cuaccacgug      360

aaggccaacg gcguggacgu gaccacccac agacaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccuggc cagccugacc accgagaucc agaucaacau cgagaucgag      480

agcagaaaga gcuacaagaa gaugcugaag gagaugggcg agguggcccc cgaguacaga      540

cacgacagcc ccgacugcgg caugaucauc cugugcaucg ccgcccuggu gaucaccaag      600

cuggccgccg gcgacagaag cggccugacc gccgugauca gaagagccaa caacgugcug      660

aagaacgaga ugaagagaua caagggccug cugcccaagg acaucgccaa cagcuucuac      720

gagguguucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

agcagcacca gaggcggcag cagaguggag ggcaucuucg ccggccuguu caugaacgcc      840

uacggcgccg gccaggugau gcugagaugg ggcgugcugg ccaagagcgu gaagaacauc      900

augcugggcc acgccagcgu gcaggccgag auggagcagg ugguggaggu guacgaguac      960

gcccagaagc ugggcggcga ggccggcuuc uaccacaucc ugaacaaccc caaggccagc     1020

cugcugagcc ugacccaguu cccccacuuc agcagcgugg ugcugggcaa cgccgccggc     1080

cugggcauca ugggcgagua cagaggcacc cccagaaacc aggaccugua cgacgccgcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacagcgu gcuggaccug     1200

accgccgagg agcuggaggc caucaagcac cagcugaacc ccaaggacaa cgacguggag     1260

cugugaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10340
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10340
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccugaaua aggaucagcu ucuguccucu agcaaauaca caauccaaag auccacgggc      180

gacucuauug auacccccaa cuaugacguc cagaagcaca ucaauaaacu cugcgggaug      240

cugcuuauua cagaggaugc uaaccauaag uucaccggac ugaucggcau gcucuacgcc      300

augagccggc uggggcgcga agacacaauu aagauccuga gagaugcggg auaucacguu      360

aaagcuaaug gcguggacgu gaccacacau cggcaggaua ucaacgggaa ggagaugaaa      420

uuugaagucc ucacccuggc cucccuuacg accgagauuc agaucaauau ugaaaucgag      480

ucucgcaaga gcuacaaaaa gaugcugaag gagaugggag aaguggcccc ugaguauaga      540

cacgacuccc cggauugugg caugauuauc cucugcauug cugcccuggu uaucacaaaa      600

cuugcugccg gcgaccggag cgggcugacc gcggugaucc gcagagccaa caauguccuc      660

aagaacgaaa ugaaacggua caagggacug cugcccaaag auauugcuaa uucuuucuau      720

gagguguuug agaagcaucc ucacuucauc gacguuuuug ugcacuucgg cauugcccaa      780

uccagcacac gcgggggauc uagagucgaa ggcaucuuug cuggacucuu caugaacgcc      840

uacggggcgg gccaggugau gcugcggugg ggcgugcuug ccaaauccgu caagaauauu      900

augcuggggc augcuagcgu ucaggccgag auggaacagg ugguggaggu cuacgaauau      960

gcucaaaagc ucggaggcga ggccggguuu uaccacaucc ugaacaaucc caaagccucu     1020

cuucuguccc ucacccaguu cccucauuuu agcuccgugg uucugggaaa cgcugcgggc     1080

cuggggauca ugggagagua ucgcggcacg cccagaaacc aggaccucua cgaugccgcu     1140

aaggccuaug ccgaacagcu gaaagagaau ggcgugauua acuacucugu ccuugaccug     1200

acagcugagg aacucgaagc caucaagcac caacugaauc cuaaagauaa cgacguggag     1260

cuuugaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10341
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10341
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacuaa gcaaagucaa auuaaacgac      120

acauuaaaca aagaccaacu cuuaucauca ucaaaauaca caauacaaag aagcaccgga      180

gacaguaucg acacaccaaa cuaugacguc caaaaacaua uaaauaaauu augcggcaug      240

cucuuaauca cagaagacgc caaccauaaa uuuacaggau uaauaggaau guuauaugca      300

augucacgac uagguagaga agacacaaua aaaauacuaa gagacgcagg cuaucacgua      360

aaagcaaaug gaguagacgu aaccacacac agacaagaca uaaauggaaa agaaaugaaa      420

uuugaaguau uaacacuagc aucacuaaca acagaaauac aaaucaacau agaaauagaa      480

ucaagaaaaa gcuacaaaaa aauguuaaaa gaaaugggag aagucgcacc agaauauaga      540

caugauucac cagacugcgg aaugauaaua cuaugcauag cagcccuagu aauuacaaaa      600

cuagcagcag gagacagaag cggauuaaca gcaguaauaa gaagagcaaa caacguacua      660

aaaaacgaaa ugaaaagaua uaaaggauua uuaccaaaag acauagcaaa cucauucuau      720

gaaguauucg aaaaacaccc ccacuuuaua gacgucuucg uacacuucgg aauagcccaa      780

ucauccacaa gaggaggauc aagagucgaa ggaauauucg caggauuauu caugaacgca      840

uauggcgcag gacaaguaau gcuaagaugg ggaguacuag caaaauccgu caaaaacaua      900

augcuaggac acgcaucagu ucaagcagaa auggaacaag uaguagaagu auacgaauac      960

gcccaaaaac uaggaggaga agcaggauuc uaccacauac uaaauaaucc aaaagcauca     1020

cuacuaagcc uaacccaauu uccccacuuc ucaaguguag uauuaggaaa ugcagcugga     1080

cuaggaauaa ugggagaaua cagaggaaca ccaagaaacc aagacuuaua cgacgcagca     1140

aaagcauacg cagagcaacu uaaagaaaac ggaguaauaa acuauagcgu acuagacuua     1200

acagcagaag aacuggaagc aauaaaacau caauuaaacc cgaaagacaa ugacguagaa     1260

uuauaaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10342
<211>  1478
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10342
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacucu cgaaaguaaa acucaacgac      120

acccucaaca aagaccaacu ccuuuccagc uccaaauaca ccauccaacg auccaccgga      180

gacuccaucg acacgcccaa cuacgacguc cagaaacaca ucaacaagcu cugcggaaug      240

cuacuaauca ccgaggacgc caaccacaaa uucacaggac uuauagggau gcucuacgcc      300

augucccgcc ucggacgcga agacacaaua aaaauccuac gagacgccgg cuaccacgua      360

aaggcaaacg gcgucgacgu caccacacac agacaagaca ucaacggaaa ggaaaugaaa      420

uucgaagucc ucacccucgc cagccuaacc accgagaucc aaaucaacau cgaaaucgaa      480

ucacgcaaau ccuacaagaa aaugcucaaa gaaaugggag aagucgcccc cgaauaccgu      540

cacgacucgc ccgacugcgg caugauaauc cuaugcaucg ccgcacucgu cauaaccaaa      600

cucgccgccg gugaccgauc aggacugaca gcagucaucc gccgagcaaa caacgugcuc      660

aaaaacgaaa ugaaacgcua caaaggccua cuccccaaag acaucgccaa cuccuucuac      720

gaagucuucg aaaaacaccc acacuucauc gacgucuucg uccacuucgg caucgcacaa      780

ucaucaacca gaggcggcag ccgcguugaa ggcaucuucg caggacucuu uaugaacgcc      840

uacggcgccg gccaagucau gcuccgcugg ggcguccugg caaaaagcgu caaaaacauc      900

augcuaggcc acgcuagcgu ccaagccgaa auggaacaag ucgucgaagu uuacgaguac      960

gcacaaaaac ucggcggcga agcaggcuuc uaccacaucc uaaacaaccc caaagccucc     1020

cugcuaucac ucacccaauu cccccacuuc uccagcgucg uccucggcaa cgccgcagga     1080

cuaggcauca ugggagaaua ccgcgggaca ccgcgcaacc aagaccucua cgacgccgcc     1140

aaagccuacg ccgaacaacu caaagaaaac ggcgucauaa acuacucagu ccucgaccuc     1200

accgccgaag aacucgaagc caucaaacac caacucaacc caaaagacaa cgacgucgaa     1260

uuauaaggac uaguguccac cugucccucc ugggcugcug gauugucucg uuuuccugcc     1320

aaauaaacag gaucagcgcu uuacagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1440

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1478


<210>  10343
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10343
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcucuua gcaaagucaa guugaaugau      120

acacucaaca aagaucaacu ucugucaucc agcaaauaca ccauccaacg gagcacagga      180

gauaguauug auacuccuaa uuaugaugug cagaaacaca ucaauaaguu auguggcaug      240

uuauuaauca cagaagaugc uaaucauaaa uucacugggu uaauagguau guuauaugcg      300

augucuaggu uaggaagaga agacaccaua aaaauacuca gagaugcggg auaucaugua      360

aaagcaaaug gaguagaugu aacaacacau cgucaagaca uuaauggaaa agaaaugaaa      420

uuugaagugu uaacauuggc aagcuuaaca acugaaauuc aaaucaacau ugagauagaa      480

ucuagaaaau ccuacaaaaa aaugcuaaaa gaaaugggag agguagcucc agaauacagg      540

caugacucuc cugauugugg gaugauaaua uuauguauag cagcauuagu aauaacuaaa      600

uuagcagcag gggacagauc uggucuuaca gccgugauua ggagagcuaa uaauguccua      660

aaaaaugaaa ugaaacguua caaaggcuua cuacccaagg acauagccaa cagcuucuau      720

gaaguguuug aaaaacaucc ccacuuuaua gauguuuuug uucauuuugg uauagcacaa      780

ucuucuacca gagguggcag uagaguugaa gggauuuuug caggauuguu uaugaaugcc      840

uauggugcag ggcaagugau guuacggugg ggagucuuag caaaaucagu uaaaaauauu      900

auguuaggac augcuagugu gcaagcagaa auggaacaag uuguugaggu uuaugaauau      960

gcccaaaaau ugggugguga agcaggauuc uaccauauau ugaacaaccc aaaagcauca     1020

uuauuaucuu ugacucaauu uccucacuuc uccaguguag uauuaggcaa ugcugcuggc     1080

cuaggcauaa ugggagagua cagagguaca ccgaggaauc aagaucuaua ugaugcagca     1140

aaggcauaug cugaacaacu caaagaaaau ggugugauua acuacagugu acuagacuug     1200

acagcagaag aacuagaggc uaucaaacau cagcuuaauc caaaagauaa ugauguagag     1260

cuuugaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10344
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10344
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcucaacgac      120

acccugaaca aggaccagcu gcucuccagc uccaaguaca ccauccagcg cagcaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu gugcgggaug      240

cugcucauca ccgaggacgc caaccacaag uucaccggcc ugaucgggau gcuguacgcg      300

augagccggc ucggccgcga ggacacgauc aagauccugc gggacgccgg guaccacgug      360

aaggccaacg gcguggacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccucgc cucccugacg accgagaucc agaucaacau cgagaucgag      480

agccggaagu ccuacaagaa gaugcugaag gagauggggg agguggcccc ggaguaccgc      540

cacgacagcc ccgacugcgg caugaucauc cucugcaucg cggcccuggu caucaccaag      600

cuggccgccg gggaccgguc cggccucacc gcggugaucc gccgggccaa caacgugcug      660

aagaacgaga ugaagcgcua caaggggcug cuccccaagg acaucgccaa cagcuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

uccagcacgc ggggcggguc ccgcgucgag ggcaucuucg ccgggcuguu caugaacgcg      840

uacggcgccg gccaggugau gcugcggugg ggcgugcucg ccaagagcgu caagaacauc      900

augcuggggc acgccuccgu gcaggccgag auggagcagg ucguggaggu guacgaguac      960

gcgcagaagc ucgggggcga ggccggguuc uaccacaucc ugaacaaccc gaaggccagc     1020

cugcuguccc ucacccaguu cccccacuuc agcagcgugg uccugggcaa cgccgccggc     1080

cuggggauca ugggcgagua ccgcgggacg ccccggaacc aggaccucua cgacgcggcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacuccgu gcuggaccuc     1200

accgccgagg agcuggaggc gaucaagcac cagcugaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10345
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10345
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccucu ccaaggucaa gcucaacgac      120

acccucaaca aggaccagcu ccucuccucc uccaaguaca ccauccagcg cuccaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu cugcggcaug      240

cuccucauca ccgaggacgc caaccacaag uucaccggcc ucaucggcau gcucuacgcc      300

augucccgcc ucggccgcga ggacaccauc aagauccucc gcgacgccgg cuaccacguc      360

aaggccaacg gcgucgacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggucc ucacccucgc cucccucacc accgagaucc agaucaacau cgagaucgag      480

ucccgcaagu ccuacaagaa gaugcucaag gagaugggcg aggucgcccc cgaguaccgc      540

cacgacuccc ccgacugcgg caugaucauc cucugcaucg ccgcccucgu caucaccaag      600

cucgccgccg gcgaccgcuc cggccucacc gccgucaucc gccgcgccaa caacguccuc      660

aagaacgaga ugaagcgcua caagggccuc cuccccaagg acaucgccaa cuccuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacgucuucg uccacuucgg caucgcccag      780

uccuccaccc gcggcggcuc ccgcgucgag ggcaucuucg ccggccucuu caugaacgcc      840

uacggcgccg gccaggucau gcuccgcugg ggcguccucg ccaaguccgu caagaacauc      900

augcucggcc acgccuccgu ccaggccgag auggagcagg ucgucgaggu cuacgaguac      960

gcccagaagc ucggcggcga ggccggcuuc uaccacaucc ucaacaaccc caaggccucc     1020

cuccucuccc ucacccaguu cccccacuuc uccuccgucg uccucggcaa cgccgccggc     1080

cucggcauca ugggcgagua ccgcggcacc ccccgcaacc aggaccucua cgacgccgcc     1140

aaggccuacg ccgagcagcu caaggagaac ggcgucauca acuacuccgu ccucgaccuc     1200

accgccgagg agcucgaggc caucaagcac cagcucaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10346
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10346
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccuuaaua aggaucagcu guuguccucu ucaaaauaca caauccaaag aaguacuggc      180

gacagcauug auacgcccaa cuaugacguc cagaagcaca uaaauaaauu augcgggaug      240

cugcuaauca ccgaggaugc uaaccauaag uucacaggac ucauugguau gcuguacgca      300

auguccaggc uuggccggga agacacuauc aagauucugc gcgaugccgg guaucacguu      360

aaagcgaaug gaguggacgu aaccacacau cgacaggaua ucaacggcaa ggagaugaaa      420

uuugaagugu ugacccucgc uucucugacu acagagauac agaucaauau ugaaaucgag      480

ucgcguaagu cauacaaaaa gaugcugaag gagaugggug aagucgcccc ugaguauaga      540

cacgacagcc cagauugugg gaugauuauc cucugcauag cagccuuagu gauuaccaaa      600

cuggcugcag gagacaggag uggccuuacg gccguuaucc ggcgcgcuaa caauguguug      660

aagaacgaaa ugaaaagaua caagggccug cuaccgaaag auauugccaa uuccuucuau      720

gaggucuuug agaagcaucc ccacuucauc gacguguuug uacacuucgg gaucgcgcaa      780

ucuagcacua ggggagguuc ccggguugaa ggcauuuuug caggacucuu caugaacgcc      840

uacggggcug gccaggugau gcugcgcugg gguguccuug ccaaaucagu gaagaauaua      900

augcuggggc augcaagugu gcaggcugag auggaacagg ucguugaggu guacgaauau      960

gcccaaaagu ugggaggcga ggcgggcuuu uaccacaucc ucaacaaucc uaaagccagc     1020

cuguuaucuc ugacccaguu cccacauuuu uccucaguag ugcucgggaa cgcagcugga     1080

cuugguauua ugggcgagua ucgagggaca cccagaaacc aggaccugua cgaugccgcu     1140

aaggccuaug cagaacaguu gaaagagaau ggagucauca acuacagcgu gcuagaccug     1200

acugccgagg aacucgaagc uauaaagcac caacugaauc cuaaagauaa cgacguugag     1260

cuuugaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10347
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10347
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcugaacgac      120

acccugaaca aggaccagcu gcugagcagc agcaaguaca ccauccagag aagcaccggc      180

gacagcaucg acacccccaa cuacgacgug cagaagcaca ucaacaagcu gugcggcaug      240

cugcugauca ccgaggacgc caaccacaag uucaccggcc ugaucggcau gcuguacgcc      300

augagcagac ugggcagaga ggacaccauc aagauccuga gagacgccgg cuaccacgug      360

aaggccaacg gcguggacgu gaccacccac agacaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccuggc cagccugacc accgagaucc agaucaacau cgagaucgag      480

agcagaaaga gcuacaagaa gaugcugaag gagaugggcg agguggcccc cgaguacaga      540

cacgacagcc ccgacugcgg caugaucauc cugugcaucg ccgcccuggu gaucaccaag      600

cuggccgccg gcgacagaag cggccugacc gccgugauca gaagagccaa caacgugcug      660

aagaacgaga ugaagagaua caagggccug cugcccaagg acaucgccaa cagcuucuac      720

gagguguucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

agcagcacca gaggcggcag cagaguggag ggcaucuucg ccggccuguu caugaacgcc      840

uacggcgccg gccaggugau gcugagaugg ggcgugcugg ccaagagcgu gaagaacauc      900

augcugggcc acgccagcgu gcaggccgag auggagcagg ugguggaggu guacgaguac      960

gcccagaagc ugggcggcga ggccggcuuc uaccacaucc ugaacaaccc caaggccagc     1020

cugcugagcc ugacccaguu cccccacuuc agcagcgugg ugcugggcaa cgccgccggc     1080

cugggcauca ugggcgagua cagaggcacc cccagaaacc aggaccugua cgacgccgcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacagcgu gcuggaccug     1200

accgccgagg agcuggaggc caucaagcac cagcugaacc ccaaggacaa cgacguggag     1260

cugugaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10348
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10348
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccugaaua aggaucagcu ucuguccucu agcaaauaca caauccaaag auccacgggc      180

gacucuauug auacccccaa cuaugacguc cagaagcaca ucaauaaacu cugcgggaug      240

cugcuuauua cagaggaugc uaaccauaag uucaccggac ugaucggcau gcucuacgcc      300

augagccggc uggggcgcga agacacaauu aagauccuga gagaugcggg auaucacguu      360

aaagcuaaug gcguggacgu gaccacacau cggcaggaua ucaacgggaa ggagaugaaa      420

uuugaagucc ucacccuggc cucccuuacg accgagauuc agaucaauau ugaaaucgag      480

ucucgcaaga gcuacaaaaa gaugcugaag gagaugggag aaguggcccc ugaguauaga      540

cacgacuccc cggauugugg caugauuauc cucugcauug cugcccuggu uaucacaaaa      600

cuugcugccg gcgaccggag cgggcugacc gcggugaucc gcagagccaa caauguccuc      660

aagaacgaaa ugaaacggua caagggacug cugcccaaag auauugcuaa uucuuucuau      720

gagguguuug agaagcaucc ucacuucauc gacguuuuug ugcacuucgg cauugcccaa      780

uccagcacac gcgggggauc uagagucgaa ggcaucuuug cuggacucuu caugaacgcc      840

uacggggcgg gccaggugau gcugcggugg ggcgugcuug ccaaauccgu caagaauauu      900

augcuggggc augcuagcgu ucaggccgag auggaacagg ugguggaggu cuacgaauau      960

gcucaaaagc ucggaggcga ggccggguuu uaccacaucc ugaacaaucc caaagccucu     1020

cuucuguccc ucacccaguu cccucauuuu agcuccgugg uucugggaaa cgcugcgggc     1080

cuggggauca ugggagagua ucgcggcacg cccagaaacc aggaccucua cgaugccgcu     1140

aaggccuaug ccgaacagcu gaaagagaau ggcgugauua acuacucugu ccuugaccug     1200

acagcugagg aacucgaagc caucaagcac caacugaauc cuaaagauaa cgacguggag     1260

cuuugaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10349
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10349
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacuaa gcaaagucaa auuaaacgac      120

acauuaaaca aagaccaacu cuuaucauca ucaaaauaca caauacaaag aagcaccgga      180

gacaguaucg acacaccaaa cuaugacguc caaaaacaua uaaauaaauu augcggcaug      240

cucuuaauca cagaagacgc caaccauaaa uuuacaggau uaauaggaau guuauaugca      300

augucacgac uagguagaga agacacaaua aaaauacuaa gagacgcagg cuaucacgua      360

aaagcaaaug gaguagacgu aaccacacac agacaagaca uaaauggaaa agaaaugaaa      420

uuugaaguau uaacacuagc aucacuaaca acagaaauac aaaucaacau agaaauagaa      480

ucaagaaaaa gcuacaaaaa aauguuaaaa gaaaugggag aagucgcacc agaauauaga      540

caugauucac cagacugcgg aaugauaaua cuaugcauag cagcccuagu aauuacaaaa      600

cuagcagcag gagacagaag cggauuaaca gcaguaauaa gaagagcaaa caacguacua      660

aaaaacgaaa ugaaaagaua uaaaggauua uuaccaaaag acauagcaaa cucauucuau      720

gaaguauucg aaaaacaccc ccacuuuaua gacgucuucg uacacuucgg aauagcccaa      780

ucauccacaa gaggaggauc aagagucgaa ggaauauucg caggauuauu caugaacgca      840

uauggcgcag gacaaguaau gcuaagaugg ggaguacuag caaaauccgu caaaaacaua      900

augcuaggac acgcaucagu ucaagcagaa auggaacaag uaguagaagu auacgaauac      960

gcccaaaaac uaggaggaga agcaggauuc uaccacauac uaaauaaucc aaaagcauca     1020

cuacuaagcc uaacccaauu uccccacuuc ucaaguguag uauuaggaaa ugcagcugga     1080

cuaggaauaa ugggagaaua cagaggaaca ccaagaaacc aagacuuaua cgacgcagca     1140

aaagcauacg cagagcaacu uaaagaaaac ggaguaauaa acuauagcgu acuagacuua     1200

acagcagaag aacuggaagc aauaaaacau caauuaaacc cgaaagacaa ugacguagaa     1260

uuauaaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10350
<211>  1545
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10350
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacucu cgaaaguaaa acucaacgac      120

acccucaaca aagaccaacu ccuuuccagc uccaaauaca ccauccaacg auccaccgga      180

gacuccaucg acacgcccaa cuacgacguc cagaaacaca ucaacaagcu cugcggaaug      240

cuacuaauca ccgaggacgc caaccacaaa uucacaggac uuauagggau gcucuacgcc      300

augucccgcc ucggacgcga agacacaaua aaaauccuac gagacgccgg cuaccacgua      360

aaggcaaacg gcgucgacgu caccacacac agacaagaca ucaacggaaa ggaaaugaaa      420

uucgaagucc ucacccucgc cagccuaacc accgagaucc aaaucaacau cgaaaucgaa      480

ucacgcaaau ccuacaagaa aaugcucaaa gaaaugggag aagucgcccc cgaauaccgu      540

cacgacucgc ccgacugcgg caugauaauc cuaugcaucg ccgcacucgu cauaaccaaa      600

cucgccgccg gugaccgauc aggacugaca gcagucaucc gccgagcaaa caacgugcuc      660

aaaaacgaaa ugaaacgcua caaaggccua cuccccaaag acaucgccaa cuccuucuac      720

gaagucuucg aaaaacaccc acacuucauc gacgucuucg uccacuucgg caucgcacaa      780

ucaucaacca gaggcggcag ccgcguugaa ggcaucuucg caggacucuu uaugaacgcc      840

uacggcgccg gccaagucau gcuccgcugg ggcguccugg caaaaagcgu caaaaacauc      900

augcuaggcc acgcuagcgu ccaagccgaa auggaacaag ucgucgaagu uuacgaguac      960

gcacaaaaac ucggcggcga agcaggcuuc uaccacaucc uaaacaaccc caaagccucc     1020

cugcuaucac ucacccaauu cccccacuuc uccagcgucg uccucggcaa cgccgcagga     1080

cuaggcauca ugggagaaua ccgcgggaca ccgcgcaacc aagaccucua cgacgccgcc     1140

aaagccuacg ccgaacaacu caaagaaaac ggcgucauaa acuacucagu ccucgaccuc     1200

accgccgaag aacucgaagc caucaaacac caacucaacc caaaagacaa cgacgucgaa     1260

uuauaaggac uaguacuggc ugcaucuccc uuuccucugu ccuccauccu ucucccagga     1320

uggugaaggg ggaccuggua cccagugauc cccaccccag gauccuaaau caugacuuac     1380

cugcuaauaa aaacucauug gaaaagugag aagaucuaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     1500

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     1545


<210>  10351
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10351
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcucuua gcaaagucaa guugaaugau      120

acacucaaca aagaucaacu ucugucaucc agcaaauaca ccauccaacg gagcacagga      180

gauaguauug auacuccuaa uuaugaugug cagaaacaca ucaauaaguu auguggcaug      240

uuauuaauca cagaagaugc uaaucauaaa uucacugggu uaauagguau guuauaugcg      300

augucuaggu uaggaagaga agacaccaua aaaauacuca gagaugcggg auaucaugua      360

aaagcaaaug gaguagaugu aacaacacau cgucaagaca uuaauggaaa agaaaugaaa      420

uuugaagugu uaacauuggc aagcuuaaca acugaaauuc aaaucaacau ugagauagaa      480

ucuagaaaau ccuacaaaaa aaugcuaaaa gaaaugggag agguagcucc agaauacagg      540

caugacucuc cugauugugg gaugauaaua uuauguauag cagcauuagu aauaacuaaa      600

uuagcagcag gggacagauc uggucuuaca gccgugauua ggagagcuaa uaauguccua      660

aaaaaugaaa ugaaacguua caaaggcuua cuacccaagg acauagccaa cagcuucuau      720

gaaguguuug aaaaacaucc ccacuuuaua gauguuuuug uucauuuugg uauagcacaa      780

ucuucuacca gagguggcag uagaguugaa gggauuuuug caggauuguu uaugaaugcc      840

uauggugcag ggcaagugau guuacggugg ggagucuuag caaaaucagu uaaaaauauu      900

auguuaggac augcuagugu gcaagcagaa auggaacaag uuguugaggu uuaugaauau      960

gcccaaaaau ugggugguga agcaggauuc uaccauauau ugaacaaccc aaaagcauca     1020

uuauuaucuu ugacucaauu uccucacuuc uccaguguag uauuaggcaa ugcugcuggc     1080

cuaggcauaa ugggagagua cagagguaca ccgaggaauc aagaucuaua ugaugcagca     1140

aaggcauaug cugaacaacu caaagaaaau ggugugauua acuacagugu acuagacuug     1200

acagcagaag aacuagaggc uaucaaacau cagcuuaauc caaaagauaa ugauguagag     1260

cuuugaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10352
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10352
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcucaacgac      120

acccugaaca aggaccagcu gcucuccagc uccaaguaca ccauccagcg cagcaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu gugcgggaug      240

cugcucauca ccgaggacgc caaccacaag uucaccggcc ugaucgggau gcuguacgcg      300

augagccggc ucggccgcga ggacacgauc aagauccugc gggacgccgg guaccacgug      360

aaggccaacg gcguggacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccucgc cucccugacg accgagaucc agaucaacau cgagaucgag      480

agccggaagu ccuacaagaa gaugcugaag gagauggggg agguggcccc ggaguaccgc      540

cacgacagcc ccgacugcgg caugaucauc cucugcaucg cggcccuggu caucaccaag      600

cuggccgccg gggaccgguc cggccucacc gcggugaucc gccgggccaa caacgugcug      660

aagaacgaga ugaagcgcua caaggggcug cuccccaagg acaucgccaa cagcuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

uccagcacgc ggggcggguc ccgcgucgag ggcaucuucg ccgggcuguu caugaacgcg      840

uacggcgccg gccaggugau gcugcggugg ggcgugcucg ccaagagcgu caagaacauc      900

augcuggggc acgccuccgu gcaggccgag auggagcagg ucguggaggu guacgaguac      960

gcgcagaagc ucgggggcga ggccggguuc uaccacaucc ugaacaaccc gaaggccagc     1020

cugcuguccc ucacccaguu cccccacuuc agcagcgugg uccugggcaa cgccgccggc     1080

cuggggauca ugggcgagua ccgcgggacg ccccggaacc aggaccucua cgacgcggcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacuccgu gcuggaccuc     1200

accgccgagg agcuggaggc gaucaagcac cagcugaacc ccaaggacaa cgacgucgag     1260

cucugaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10353
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10353
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccucu ccaaggucaa gcucaacgac      120

acccucaaca aggaccagcu ccucuccucc uccaaguaca ccauccagcg cuccaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu cugcggcaug      240

cuccucauca ccgaggacgc caaccacaag uucaccggcc ucaucggcau gcucuacgcc      300

augucccgcc ucggccgcga ggacaccauc aagauccucc gcgacgccgg cuaccacguc      360

aaggccaacg gcgucgacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggucc ucacccucgc cucccucacc accgagaucc agaucaacau cgagaucgag      480

ucccgcaagu ccuacaagaa gaugcucaag gagaugggcg aggucgcccc cgaguaccgc      540

cacgacuccc ccgacugcgg caugaucauc cucugcaucg ccgcccucgu caucaccaag      600

cucgccgccg gcgaccgcuc cggccucacc gccgucaucc gccgcgccaa caacguccuc      660

aagaacgaga ugaagcgcua caagggccuc cuccccaagg acaucgccaa cuccuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacgucuucg uccacuucgg caucgcccag      780

uccuccaccc gcggcggcuc ccgcgucgag ggcaucuucg ccggccucuu caugaacgcc      840

uacggcgccg gccaggucau gcuccgcugg ggcguccucg ccaaguccgu caagaacauc      900

augcucggcc acgccuccgu ccaggccgag auggagcagg ucgucgaggu cuacgaguac      960

gcccagaagc ucggcggcga ggccggcuuc uaccacaucc ucaacaaccc caaggccucc     1020

cuccucuccc ucacccaguu cccccacuuc uccuccgucg uccucggcaa cgccgccggc     1080

cucggcauca ugggcgagua ccgcggcacc ccccgcaacc aggaccucua cgacgccgcc     1140

aaggccuacg ccgagcagcu caaggagaac ggcgucauca acuacuccgu ccucgaccuc     1200

accgccgagg agcucgaggc caucaagcac cagcucaacc ccaaggacaa cgacgucgag     1260

cucugaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10354
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10354
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccuuaaua aggaucagcu guuguccucu ucaaaauaca caauccaaag aaguacuggc      180

gacagcauug auacgcccaa cuaugacguc cagaagcaca uaaauaaauu augcgggaug      240

cugcuaauca ccgaggaugc uaaccauaag uucacaggac ucauugguau gcuguacgca      300

auguccaggc uuggccggga agacacuauc aagauucugc gcgaugccgg guaucacguu      360

aaagcgaaug gaguggacgu aaccacacau cgacaggaua ucaacggcaa ggagaugaaa      420

uuugaagugu ugacccucgc uucucugacu acagagauac agaucaauau ugaaaucgag      480

ucgcguaagu cauacaaaaa gaugcugaag gagaugggug aagucgcccc ugaguauaga      540

cacgacagcc cagauugugg gaugauuauc cucugcauag cagccuuagu gauuaccaaa      600

cuggcugcag gagacaggag uggccuuacg gccguuaucc ggcgcgcuaa caauguguug      660

aagaacgaaa ugaaaagaua caagggccug cuaccgaaag auauugccaa uuccuucuau      720

gaggucuuug agaagcaucc ccacuucauc gacguguuug uacacuucgg gaucgcgcaa      780

ucuagcacua ggggagguuc ccggguugaa ggcauuuuug caggacucuu caugaacgcc      840

uacggggcug gccaggugau gcugcgcugg gguguccuug ccaaaucagu gaagaauaua      900

augcuggggc augcaagugu gcaggcugag auggaacagg ucguugaggu guacgaauau      960

gcccaaaagu ugggaggcga ggcgggcuuu uaccacaucc ucaacaaucc uaaagccagc     1020

cuguuaucuc ugacccaguu cccacauuuu uccucaguag ugcucgggaa cgcagcugga     1080

cuugguauua ugggcgagua ucgagggaca cccagaaacc aggaccugua cgaugccgcu     1140

aaggccuaug cagaacaguu gaaagagaau ggagucauca acuacagcgu gcuagaccug     1200

acugccgagg aacucgaagc uauaaagcac caacugaauc cuaaagauaa cgacguugag     1260

cuuugaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10355
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10355
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcugaacgac      120

acccugaaca aggaccagcu gcugagcagc agcaaguaca ccauccagag aagcaccggc      180

gacagcaucg acacccccaa cuacgacgug cagaagcaca ucaacaagcu gugcggcaug      240

cugcugauca ccgaggacgc caaccacaag uucaccggcc ugaucggcau gcuguacgcc      300

augagcagac ugggcagaga ggacaccauc aagauccuga gagacgccgg cuaccacgug      360

aaggccaacg gcguggacgu gaccacccac agacaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccuggc cagccugacc accgagaucc agaucaacau cgagaucgag      480

agcagaaaga gcuacaagaa gaugcugaag gagaugggcg agguggcccc cgaguacaga      540

cacgacagcc ccgacugcgg caugaucauc cugugcaucg ccgcccuggu gaucaccaag      600

cuggccgccg gcgacagaag cggccugacc gccgugauca gaagagccaa caacgugcug      660

aagaacgaga ugaagagaua caagggccug cugcccaagg acaucgccaa cagcuucuac      720

gagguguucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

agcagcacca gaggcggcag cagaguggag ggcaucuucg ccggccuguu caugaacgcc      840

uacggcgccg gccaggugau gcugagaugg ggcgugcugg ccaagagcgu gaagaacauc      900

augcugggcc acgccagcgu gcaggccgag auggagcagg ugguggaggu guacgaguac      960

gcccagaagc ugggcggcga ggccggcuuc uaccacaucc ugaacaaccc caaggccagc     1020

cugcugagcc ugacccaguu cccccacuuc agcagcgugg ugcugggcaa cgccgccggc     1080

cugggcauca ugggcgagua cagaggcacc cccagaaacc aggaccugua cgacgccgcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacagcgu gcuggaccug     1200

accgccgagg agcuggaggc caucaagcac cagcugaacc ccaaggacaa cgacguggag     1260

cugugaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10356
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10356
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccugaaua aggaucagcu ucuguccucu agcaaauaca caauccaaag auccacgggc      180

gacucuauug auacccccaa cuaugacguc cagaagcaca ucaauaaacu cugcgggaug      240

cugcuuauua cagaggaugc uaaccauaag uucaccggac ugaucggcau gcucuacgcc      300

augagccggc uggggcgcga agacacaauu aagauccuga gagaugcggg auaucacguu      360

aaagcuaaug gcguggacgu gaccacacau cggcaggaua ucaacgggaa ggagaugaaa      420

uuugaagucc ucacccuggc cucccuuacg accgagauuc agaucaauau ugaaaucgag      480

ucucgcaaga gcuacaaaaa gaugcugaag gagaugggag aaguggcccc ugaguauaga      540

cacgacuccc cggauugugg caugauuauc cucugcauug cugcccuggu uaucacaaaa      600

cuugcugccg gcgaccggag cgggcugacc gcggugaucc gcagagccaa caauguccuc      660

aagaacgaaa ugaaacggua caagggacug cugcccaaag auauugcuaa uucuuucuau      720

gagguguuug agaagcaucc ucacuucauc gacguuuuug ugcacuucgg cauugcccaa      780

uccagcacac gcgggggauc uagagucgaa ggcaucuuug cuggacucuu caugaacgcc      840

uacggggcgg gccaggugau gcugcggugg ggcgugcuug ccaaauccgu caagaauauu      900

augcuggggc augcuagcgu ucaggccgag auggaacagg ugguggaggu cuacgaauau      960

gcucaaaagc ucggaggcga ggccggguuu uaccacaucc ugaacaaucc caaagccucu     1020

cuucuguccc ucacccaguu cccucauuuu agcuccgugg uucugggaaa cgcugcgggc     1080

cuggggauca ugggagagua ucgcggcacg cccagaaacc aggaccucua cgaugccgcu     1140

aaggccuaug ccgaacagcu gaaagagaau ggcgugauua acuacucugu ccuugaccug     1200

acagcugagg aacucgaagc caucaagcac caacugaauc cuaaagauaa cgacguggag     1260

cuuugaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10357
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10357
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacuaa gcaaagucaa auuaaacgac      120

acauuaaaca aagaccaacu cuuaucauca ucaaaauaca caauacaaag aagcaccgga      180

gacaguaucg acacaccaaa cuaugacguc caaaaacaua uaaauaaauu augcggcaug      240

cucuuaauca cagaagacgc caaccauaaa uuuacaggau uaauaggaau guuauaugca      300

augucacgac uagguagaga agacacaaua aaaauacuaa gagacgcagg cuaucacgua      360

aaagcaaaug gaguagacgu aaccacacac agacaagaca uaaauggaaa agaaaugaaa      420

uuugaaguau uaacacuagc aucacuaaca acagaaauac aaaucaacau agaaauagaa      480

ucaagaaaaa gcuacaaaaa aauguuaaaa gaaaugggag aagucgcacc agaauauaga      540

caugauucac cagacugcgg aaugauaaua cuaugcauag cagcccuagu aauuacaaaa      600

cuagcagcag gagacagaag cggauuaaca gcaguaauaa gaagagcaaa caacguacua      660

aaaaacgaaa ugaaaagaua uaaaggauua uuaccaaaag acauagcaaa cucauucuau      720

gaaguauucg aaaaacaccc ccacuuuaua gacgucuucg uacacuucgg aauagcccaa      780

ucauccacaa gaggaggauc aagagucgaa ggaauauucg caggauuauu caugaacgca      840

uauggcgcag gacaaguaau gcuaagaugg ggaguacuag caaaauccgu caaaaacaua      900

augcuaggac acgcaucagu ucaagcagaa auggaacaag uaguagaagu auacgaauac      960

gcccaaaaac uaggaggaga agcaggauuc uaccacauac uaaauaaucc aaaagcauca     1020

cuacuaagcc uaacccaauu uccccacuuc ucaaguguag uauuaggaaa ugcagcugga     1080

cuaggaauaa ugggagaaua cagaggaaca ccaagaaacc aagacuuaua cgacgcagca     1140

aaagcauacg cagagcaacu uaaagaaaac ggaguaauaa acuauagcgu acuagacuua     1200

acagcagaag aacuggaagc aauaaaacau caauuaaacc cgaaagacaa ugacguagaa     1260

uuauaaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10358
<211>  1761
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10358
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacucu cgaaaguaaa acucaacgac      120

acccucaaca aagaccaacu ccuuuccagc uccaaauaca ccauccaacg auccaccgga      180

gacuccaucg acacgcccaa cuacgacguc cagaaacaca ucaacaagcu cugcggaaug      240

cuacuaauca ccgaggacgc caaccacaaa uucacaggac uuauagggau gcucuacgcc      300

augucccgcc ucggacgcga agacacaaua aaaauccuac gagacgccgg cuaccacgua      360

aaggcaaacg gcgucgacgu caccacacac agacaagaca ucaacggaaa ggaaaugaaa      420

uucgaagucc ucacccucgc cagccuaacc accgagaucc aaaucaacau cgaaaucgaa      480

ucacgcaaau ccuacaagaa aaugcucaaa gaaaugggag aagucgcccc cgaauaccgu      540

cacgacucgc ccgacugcgg caugauaauc cuaugcaucg ccgcacucgu cauaaccaaa      600

cucgccgccg gugaccgauc aggacugaca gcagucaucc gccgagcaaa caacgugcuc      660

aaaaacgaaa ugaaacgcua caaaggccua cuccccaaag acaucgccaa cuccuucuac      720

gaagucuucg aaaaacaccc acacuucauc gacgucuucg uccacuucgg caucgcacaa      780

ucaucaacca gaggcggcag ccgcguugaa ggcaucuucg caggacucuu uaugaacgcc      840

uacggcgccg gccaagucau gcuccgcugg ggcguccugg caaaaagcgu caaaaacauc      900

augcuaggcc acgcuagcgu ccaagccgaa auggaacaag ucgucgaagu uuacgaguac      960

gcacaaaaac ucggcggcga agcaggcuuc uaccacaucc uaaacaaccc caaagccucc     1020

cugcuaucac ucacccaauu cccccacuuc uccagcgucg uccucggcaa cgccgcagga     1080

cuaggcauca ugggagaaua ccgcgggaca ccgcgcaacc aagaccucua cgacgccgcc     1140

aaagccuacg ccgaacaacu caaagaaaac ggcgucauaa acuacucagu ccucgaccuc     1200

accgccgaag aacucgaagc caucaaacac caacucaacc caaaagacaa cgacgucgaa     1260

uuauaaggac uagugaaggg aacacccaaa uuuaauucag ccuuaagcac aauuaauuaa     1320

gagugaaacg uaauuguaca agcaguuggu cacccaccau agggcaugau caacaccgca     1380

accuuuccuu uuucccccag ugauucugaa aaaccccucu ucccuucagc uugcuuagau     1440

guuccaaauu uaguaagcuu aaggcggccu acagaagaaa aagaaaaaaa aggccacaaa     1500

aguucccucu cacuuucagu aaauaaaaua aaagcagcaa cagaaauaaa gaaauaaaug     1560

aaauucaaaa ugaaauaaau auuguguugu gcagcauuaa aaaaucaaua aaaauuaaaa     1620

augagcaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1740

cuuuucagag ccaccagaau u                                               1761


<210>  10359
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10359
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcucuua gcaaagucaa guugaaugau      120

acacucaaca aagaucaacu ucugucaucc agcaaauaca ccauccaacg gagcacagga      180

gauaguauug auacuccuaa uuaugaugug cagaaacaca ucaauaaguu auguggcaug      240

uuauuaauca cagaagaugc uaaucauaaa uucacugggu uaauagguau guuauaugcg      300

augucuaggu uaggaagaga agacaccaua aaaauacuca gagaugcggg auaucaugua      360

aaagcaaaug gaguagaugu aacaacacau cgucaagaca uuaauggaaa agaaaugaaa      420

uuugaagugu uaacauuggc aagcuuaaca acugaaauuc aaaucaacau ugagauagaa      480

ucuagaaaau ccuacaaaaa aaugcuaaaa gaaaugggag agguagcucc agaauacagg      540

caugacucuc cugauugugg gaugauaaua uuauguauag cagcauuagu aauaacuaaa      600

uuagcagcag gggacagauc uggucuuaca gccgugauua ggagagcuaa uaauguccua      660

aaaaaugaaa ugaaacguua caaaggcuua cuacccaagg acauagccaa cagcuucuau      720

gaaguguuug aaaaacaucc ccacuuuaua gauguuuuug uucauuuugg uauagcacaa      780

ucuucuacca gagguggcag uagaguugaa gggauuuuug caggauuguu uaugaaugcc      840

uauggugcag ggcaagugau guuacggugg ggagucuuag caaaaucagu uaaaaauauu      900

auguuaggac augcuagugu gcaagcagaa auggaacaag uuguugaggu uuaugaauau      960

gcccaaaaau ugggugguga agcaggauuc uaccauauau ugaacaaccc aaaagcauca     1020

uuauuaucuu ugacucaauu uccucacuuc uccaguguag uauuaggcaa ugcugcuggc     1080

cuaggcauaa ugggagagua cagagguaca ccgaggaauc aagaucuaua ugaugcagca     1140

aaggcauaug cugaacaacu caaagaaaau ggugugauua acuacagugu acuagacuug     1200

acagcagaag aacuagaggc uaucaaacau cagcuuaauc caaaagauaa ugauguagag     1260

cuuugaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10360
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10360
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcucaacgac      120

acccugaaca aggaccagcu gcucuccagc uccaaguaca ccauccagcg cagcaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu gugcgggaug      240

cugcucauca ccgaggacgc caaccacaag uucaccggcc ugaucgggau gcuguacgcg      300

augagccggc ucggccgcga ggacacgauc aagauccugc gggacgccgg guaccacgug      360

aaggccaacg gcguggacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccucgc cucccugacg accgagaucc agaucaacau cgagaucgag      480

agccggaagu ccuacaagaa gaugcugaag gagauggggg agguggcccc ggaguaccgc      540

cacgacagcc ccgacugcgg caugaucauc cucugcaucg cggcccuggu caucaccaag      600

cuggccgccg gggaccgguc cggccucacc gcggugaucc gccgggccaa caacgugcug      660

aagaacgaga ugaagcgcua caaggggcug cuccccaagg acaucgccaa cagcuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

uccagcacgc ggggcggguc ccgcgucgag ggcaucuucg ccgggcuguu caugaacgcg      840

uacggcgccg gccaggugau gcugcggugg ggcgugcucg ccaagagcgu caagaacauc      900

augcuggggc acgccuccgu gcaggccgag auggagcagg ucguggaggu guacgaguac      960

gcgcagaagc ucgggggcga ggccggguuc uaccacaucc ugaacaaccc gaaggccagc     1020

cugcuguccc ucacccaguu cccccacuuc agcagcgugg uccugggcaa cgccgccggc     1080

cuggggauca ugggcgagua ccgcgggacg ccccggaacc aggaccucua cgacgcggcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacuccgu gcuggaccuc     1200

accgccgagg agcuggaggc gaucaagcac cagcugaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10361
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10361
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccucu ccaaggucaa gcucaacgac      120

acccucaaca aggaccagcu ccucuccucc uccaaguaca ccauccagcg cuccaccggc      180

gacuccaucg acacccccaa cuacgacguc cagaagcaca ucaacaagcu cugcggcaug      240

cuccucauca ccgaggacgc caaccacaag uucaccggcc ucaucggcau gcucuacgcc      300

augucccgcc ucggccgcga ggacaccauc aagauccucc gcgacgccgg cuaccacguc      360

aaggccaacg gcgucgacgu caccacccac cgccaggaca ucaacggcaa ggagaugaag      420

uucgaggucc ucacccucgc cucccucacc accgagaucc agaucaacau cgagaucgag      480

ucccgcaagu ccuacaagaa gaugcucaag gagaugggcg aggucgcccc cgaguaccgc      540

cacgacuccc ccgacugcgg caugaucauc cucugcaucg ccgcccucgu caucaccaag      600

cucgccgccg gcgaccgcuc cggccucacc gccgucaucc gccgcgccaa caacguccuc      660

aagaacgaga ugaagcgcua caagggccuc cuccccaagg acaucgccaa cuccuucuac      720

gaggucuucg agaagcaccc ccacuucauc gacgucuucg uccacuucgg caucgcccag      780

uccuccaccc gcggcggcuc ccgcgucgag ggcaucuucg ccggccucuu caugaacgcc      840

uacggcgccg gccaggucau gcuccgcugg ggcguccucg ccaaguccgu caagaacauc      900

augcucggcc acgccuccgu ccaggccgag auggagcagg ucgucgaggu cuacgaguac      960

gcccagaagc ucggcggcga ggccggcuuc uaccacaucc ucaacaaccc caaggccucc     1020

cuccucuccc ucacccaguu cccccacuuc uccuccgucg uccucggcaa cgccgccggc     1080

cucggcauca ugggcgagua ccgcggcacc ccccgcaacc aggaccucua cgacgccgcc     1140

aaggccuacg ccgagcagcu caaggagaac ggcgucauca acuacuccgu ccucgaccuc     1200

accgccgagg agcucgaggc caucaagcac cagcucaacc ccaaggacaa cgacgucgag     1260

cucugaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10362
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10362
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccuuaaua aggaucagcu guuguccucu ucaaaauaca caauccaaag aaguacuggc      180

gacagcauug auacgcccaa cuaugacguc cagaagcaca uaaauaaauu augcgggaug      240

cugcuaauca ccgaggaugc uaaccauaag uucacaggac ucauugguau gcuguacgca      300

auguccaggc uuggccggga agacacuauc aagauucugc gcgaugccgg guaucacguu      360

aaagcgaaug gaguggacgu aaccacacau cgacaggaua ucaacggcaa ggagaugaaa      420

uuugaagugu ugacccucgc uucucugacu acagagauac agaucaauau ugaaaucgag      480

ucgcguaagu cauacaaaaa gaugcugaag gagaugggug aagucgcccc ugaguauaga      540

cacgacagcc cagauugugg gaugauuauc cucugcauag cagccuuagu gauuaccaaa      600

cuggcugcag gagacaggag uggccuuacg gccguuaucc ggcgcgcuaa caauguguug      660

aagaacgaaa ugaaaagaua caagggccug cuaccgaaag auauugccaa uuccuucuau      720

gaggucuuug agaagcaucc ccacuucauc gacguguuug uacacuucgg gaucgcgcaa      780

ucuagcacua ggggagguuc ccggguugaa ggcauuuuug caggacucuu caugaacgcc      840

uacggggcug gccaggugau gcugcgcugg gguguccuug ccaaaucagu gaagaauaua      900

augcuggggc augcaagugu gcaggcugag auggaacagg ucguugaggu guacgaauau      960

gcccaaaagu ugggaggcga ggcgggcuuu uaccacaucc ucaacaaucc uaaagccagc     1020

cuguuaucuc ugacccaguu cccacauuuu uccucaguag ugcucgggaa cgcagcugga     1080

cuugguauua ugggcgagua ucgagggaca cccagaaacc aggaccugua cgaugccgcu     1140

aaggccuaug cagaacaguu gaaagagaau ggagucauca acuacagcgu gcuagaccug     1200

acugccgagg aacucgaagc uauaaagcac caacugaauc cuaaagauaa cgacguugag     1260

cuuugaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10363
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10363
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa gcugaacgac      120

acccugaaca aggaccagcu gcugagcagc agcaaguaca ccauccagag aagcaccggc      180

gacagcaucg acacccccaa cuacgacgug cagaagcaca ucaacaagcu gugcggcaug      240

cugcugauca ccgaggacgc caaccacaag uucaccggcc ugaucggcau gcuguacgcc      300

augagcagac ugggcagaga ggacaccauc aagauccuga gagacgccgg cuaccacgug      360

aaggccaacg gcguggacgu gaccacccac agacaggaca ucaacggcaa ggagaugaag      420

uucgaggugc ugacccuggc cagccugacc accgagaucc agaucaacau cgagaucgag      480

agcagaaaga gcuacaagaa gaugcugaag gagaugggcg agguggcccc cgaguacaga      540

cacgacagcc ccgacugcgg caugaucauc cugugcaucg ccgcccuggu gaucaccaag      600

cuggccgccg gcgacagaag cggccugacc gccgugauca gaagagccaa caacgugcug      660

aagaacgaga ugaagagaua caagggccug cugcccaagg acaucgccaa cagcuucuac      720

gagguguucg agaagcaccc ccacuucauc gacguguucg ugcacuucgg caucgcccag      780

agcagcacca gaggcggcag cagaguggag ggcaucuucg ccggccuguu caugaacgcc      840

uacggcgccg gccaggugau gcugagaugg ggcgugcugg ccaagagcgu gaagaacauc      900

augcugggcc acgccagcgu gcaggccgag auggagcagg ugguggaggu guacgaguac      960

gcccagaagc ugggcggcga ggccggcuuc uaccacaucc ugaacaaccc caaggccagc     1020

cugcugagcc ugacccaguu cccccacuuc agcagcgugg ugcugggcaa cgccgccggc     1080

cugggcauca ugggcgagua cagaggcacc cccagaaacc aggaccugua cgacgccgcc     1140

aaggccuacg ccgagcagcu gaaggagaac ggcgugauca acuacagcgu gcuggaccug     1200

accgccgagg agcuggaggc caucaagcac cagcugaacc ccaaggacaa cgacguggag     1260

cugugaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10364
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10364
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcccuga gcaaggugaa acucaacgac      120

acccugaaua aggaucagcu ucuguccucu agcaaauaca caauccaaag auccacgggc      180

gacucuauug auacccccaa cuaugacguc cagaagcaca ucaauaaacu cugcgggaug      240

cugcuuauua cagaggaugc uaaccauaag uucaccggac ugaucggcau gcucuacgcc      300

augagccggc uggggcgcga agacacaauu aagauccuga gagaugcggg auaucacguu      360

aaagcuaaug gcguggacgu gaccacacau cggcaggaua ucaacgggaa ggagaugaaa      420

uuugaagucc ucacccuggc cucccuuacg accgagauuc agaucaauau ugaaaucgag      480

ucucgcaaga gcuacaaaaa gaugcugaag gagaugggag aaguggcccc ugaguauaga      540

cacgacuccc cggauugugg caugauuauc cucugcauug cugcccuggu uaucacaaaa      600

cuugcugccg gcgaccggag cgggcugacc gcggugaucc gcagagccaa caauguccuc      660

aagaacgaaa ugaaacggua caagggacug cugcccaaag auauugcuaa uucuuucuau      720

gagguguuug agaagcaucc ucacuucauc gacguuuuug ugcacuucgg cauugcccaa      780

uccagcacac gcgggggauc uagagucgaa ggcaucuuug cuggacucuu caugaacgcc      840

uacggggcgg gccaggugau gcugcggugg ggcgugcuug ccaaauccgu caagaauauu      900

augcuggggc augcuagcgu ucaggccgag auggaacagg ugguggaggu cuacgaauau      960

gcucaaaagc ucggaggcga ggccggguuu uaccacaucc ugaacaaucc caaagccucu     1020

cuucuguccc ucacccaguu cccucauuuu agcuccgugg uucugggaaa cgcugcgggc     1080

cuggggauca ugggagagua ucgcggcacg cccagaaacc aggaccucua cgaugccgcu     1140

aaggccuaug ccgaacagcu gaaagagaau ggcgugauua acuacucugu ccuugaccug     1200

acagcugagg aacucgaagc caucaagcac caacugaauc cuaaagauaa cgacguggag     1260

cuuugaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10365
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10365
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacuaa gcaaagucaa auuaaacgac      120

acauuaaaca aagaccaacu cuuaucauca ucaaaauaca caauacaaag aagcaccgga      180

gacaguaucg acacaccaaa cuaugacguc caaaaacaua uaaauaaauu augcggcaug      240

cucuuaauca cagaagacgc caaccauaaa uuuacaggau uaauaggaau guuauaugca      300

augucacgac uagguagaga agacacaaua aaaauacuaa gagacgcagg cuaucacgua      360

aaagcaaaug gaguagacgu aaccacacac agacaagaca uaaauggaaa agaaaugaaa      420

uuugaaguau uaacacuagc aucacuaaca acagaaauac aaaucaacau agaaauagaa      480

ucaagaaaaa gcuacaaaaa aauguuaaaa gaaaugggag aagucgcacc agaauauaga      540

caugauucac cagacugcgg aaugauaaua cuaugcauag cagcccuagu aauuacaaaa      600

cuagcagcag gagacagaag cggauuaaca gcaguaauaa gaagagcaaa caacguacua      660

aaaaacgaaa ugaaaagaua uaaaggauua uuaccaaaag acauagcaaa cucauucuau      720

gaaguauucg aaaaacaccc ccacuuuaua gacgucuucg uacacuucgg aauagcccaa      780

ucauccacaa gaggaggauc aagagucgaa ggaauauucg caggauuauu caugaacgca      840

uauggcgcag gacaaguaau gcuaagaugg ggaguacuag caaaauccgu caaaaacaua      900

augcuaggac acgcaucagu ucaagcagaa auggaacaag uaguagaagu auacgaauac      960

gcccaaaaac uaggaggaga agcaggauuc uaccacauac uaaauaaucc aaaagcauca     1020

cuacuaagcc uaacccaauu uccccacuuc ucaaguguag uauuaggaaa ugcagcugga     1080

cuaggaauaa ugggagaaua cagaggaaca ccaagaaacc aagacuuaua cgacgcagca     1140

aaagcauacg cagagcaacu uaaagaaaac ggaguaauaa acuauagcgu acuagacuua     1200

acagcagaag aacuggaagc aauaaaacau caauuaaacc cgaaagacaa ugacguagaa     1260

uuauaaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10366
<211>  1541
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10366
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggcacucu cgaaaguaaa acucaacgac      120

acccucaaca aagaccaacu ccuuuccagc uccaaauaca ccauccaacg auccaccgga      180

gacuccaucg acacgcccaa cuacgacguc cagaaacaca ucaacaagcu cugcggaaug      240

cuacuaauca ccgaggacgc caaccacaaa uucacaggac uuauagggau gcucuacgcc      300

augucccgcc ucggacgcga agacacaaua aaaauccuac gagacgccgg cuaccacgua      360

aaggcaaacg gcgucgacgu caccacacac agacaagaca ucaacggaaa ggaaaugaaa      420

uucgaagucc ucacccucgc cagccuaacc accgagaucc aaaucaacau cgaaaucgaa      480

ucacgcaaau ccuacaagaa aaugcucaaa gaaaugggag aagucgcccc cgaauaccgu      540

cacgacucgc ccgacugcgg caugauaauc cuaugcaucg ccgcacucgu cauaaccaaa      600

cucgccgccg gugaccgauc aggacugaca gcagucaucc gccgagcaaa caacgugcuc      660

aaaaacgaaa ugaaacgcua caaaggccua cuccccaaag acaucgccaa cuccuucuac      720

gaagucuucg aaaaacaccc acacuucauc gacgucuucg uccacuucgg caucgcacaa      780

ucaucaacca gaggcggcag ccgcguugaa ggcaucuucg caggacucuu uaugaacgcc      840

uacggcgccg gccaagucau gcuccgcugg ggcguccugg caaaaagcgu caaaaacauc      900

augcuaggcc acgcuagcgu ccaagccgaa auggaacaag ucgucgaagu uuacgaguac      960

gcacaaaaac ucggcggcga agcaggcuuc uaccacaucc uaaacaaccc caaagccucc     1020

cugcuaucac ucacccaauu cccccacuuc uccagcgucg uccucggcaa cgccgcagga     1080

cuaggcauca ugggagaaua ccgcgggaca ccgcgcaacc aagaccucua cgacgccgcc     1140

aaagccuacg ccgaacaacu caaagaaaac ggcgucauaa acuacucagu ccucgaccuc     1200

accgccgaag aacucgaagc caucaaacac caacucaacc caaaagacaa cgacgucgaa     1260

uuauaaggac uaguggaagc auuuuccugg cugauuaaaa gaaauuacuc agcuaugguc     1320

aucuguuccu guuagaaggc uaugcagcau auuauauacu augcgcaugu uaugaaaugc     1380

auaauaaaaa auuuuaaaaa aucuaaaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1500

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1541


<210>  10367
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10367
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucuuagca aagucaaguu gaaugauaca cucaacaaag      120

aucaacuucu gucauccagc aaauacacca uccaacggag cacaggagau aguauugaua      180

cuccuaauua ugaugugcag aaacacauca auaaguuaug uggcauguua uuaaucacag      240

aagaugcuaa ucauaaauuc acuggguuaa uagguauguu auaugcgaug ucuagguuag      300

gaagagaaga caccauaaaa auacucagag augcgggaua ucauguaaaa gcaaauggag      360

uagauguaac aacacaucgu caagacauua auggaaaaga aaugaaauuu gaaguguuaa      420

cauuggcaag cuuaacaacu gaaauucaaa ucaacauuga gauagaaucu agaaaauccu      480

acaaaaaaau gcuaaaagaa augggagagg uagcuccaga auacaggcau gacucuccug      540

auugugggau gauaauauua uguauagcag cauuaguaau aacuaaauua gcagcagggg      600

acagaucugg ucuuacagcc gugauuagga gagcuaauaa uguccuaaaa aaugaaauga      660

aacguuacaa aggcuuacua cccaaggaca uagccaacag cuucuaugaa guguuugaaa      720

aacaucccca cuuuauagau guuuuuguuc auuuugguau agcacaaucu ucuaccagag      780

guggcaguag aguugaaggg auuuuugcag gauuguuuau gaaugccuau ggugcagggc      840

aagugauguu acggugggga gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug      900

cuagugugca agcagaaaug gaacaaguug uugagguuua ugaauaugcc caaaaauugg      960

guggugaagc aggauucuac cauauauuga acaacccaaa agcaucauua uuaucuuuga     1020

cucaauuucc ucacuucucc aguguaguau uaggcaaugc ugcuggccua ggcauaaugg     1080

gagaguacag agguacaccg aggaaucaag aucuauauga ugcagcaaag gcauaugcug     1140

aacaacucaa agaaaauggu gugauuaacu acaguguacu agacuugaca gcagaagaac     1200

uagaggcuau caaacaucag cuuaauccaa aagauaauga uguagagcuu ugaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10368
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10368
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu caacgacacc cugaacaagg      120

accagcugcu cuccagcucc aaguacacca uccagcgcag caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcugug cgggaugcug cucaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucgggaugcu guacgcgaug agccggcucg      300

gccgcgagga cacgaucaag auccugcggg acgccgggua ccacgugaag gccaacggcg      360

uggacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccucgccuc ccugacgacc gagauccaga ucaacaucga gaucgagagc cggaaguccu      480

acaagaagau gcugaaggag augggggagg uggccccgga guaccgccac gacagccccg      540

acugcggcau gaucauccuc ugcaucgcgg cccuggucau caccaagcug gccgccgggg      600

accgguccgg ccucaccgcg gugauccgcc gggccaacaa cgugcugaag aacgagauga      660

agcgcuacaa ggggcugcuc cccaaggaca ucgccaacag cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagucc agcacgcggg      780

gcgggucccg cgucgagggc aucuucgccg ggcuguucau gaacgcguac ggcgccggcc      840

aggugaugcu gcgguggggc gugcucgcca agagcgucaa gaacaucaug cuggggcacg      900

ccuccgugca ggccgagaug gagcaggucg uggaggugua cgaguacgcg cagaagcucg      960

ggggcgaggc cggguucuac cacauccuga acaacccgaa ggccagccug cugucccuca     1020

cccaguuccc ccacuucagc agcguggucc ugggcaacgc cgccggccug gggaucaugg     1080

gcgaguaccg cgggacgccc cggaaccagg accucuacga cgcggccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acuccgugcu ggaccucacc gccgaggagc     1200

uggaggcgau caagcaccag cugaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10369
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10369
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccucucca aggucaagcu caacgacacc cucaacaagg      120

accagcuccu cuccuccucc aaguacacca uccagcgcuc caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcucug cggcaugcuc cucaucaccg      240

aggacgccaa ccacaaguuc accggccuca ucggcaugcu cuacgccaug ucccgccucg      300

gccgcgagga caccaucaag auccuccgcg acgccggcua ccacgucaag gccaacggcg      360

ucgacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gagguccuca      420

cccucgccuc ccucaccacc gagauccaga ucaacaucga gaucgagucc cgcaaguccu      480

acaagaagau gcucaaggag augggcgagg ucgcccccga guaccgccac gacucccccg      540

acugcggcau gaucauccuc ugcaucgccg cccucgucau caccaagcuc gccgccggcg      600

accgcuccgg ccucaccgcc gucauccgcc gcgccaacaa cguccucaag aacgagauga      660

agcgcuacaa gggccuccuc cccaaggaca ucgccaacuc cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac gucuucgucc acuucggcau cgcccagucc uccacccgcg      780

gcggcucccg cgucgagggc aucuucgccg gccucuucau gaacgccuac ggcgccggcc      840

aggucaugcu ccgcuggggc guccucgcca aguccgucaa gaacaucaug cucggccacg      900

ccuccgucca ggccgagaug gagcaggucg ucgaggucua cgaguacgcc cagaagcucg      960

gcggcgaggc cggcuucuac cacauccuca acaaccccaa ggccucccuc cucucccuca     1020

cccaguuccc ccacuucucc uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg     1080

gcgaguaccg cggcaccccc cgcaaccagg accucuacga cgccgccaag gccuacgccg     1140

agcagcucaa ggagaacggc gucaucaacu acuccguccu cgaccucacc gccgaggagc     1200

ucgaggccau caagcaccag cucaacccca aggacaacga cgucgagcuc ugaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10370
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10370
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cuuaauaagg      120

aucagcuguu guccucuuca aaauacacaa uccaaagaag uacuggcgac agcauugaua      180

cgcccaacua ugacguccag aagcacauaa auaaauuaug cgggaugcug cuaaucaccg      240

aggaugcuaa ccauaaguuc acaggacuca uugguaugcu guacgcaaug uccaggcuug      300

gccgggaaga cacuaucaag auucugcgcg augccgggua ucacguuaaa gcgaauggag      360

uggacguaac cacacaucga caggauauca acggcaagga gaugaaauuu gaaguguuga      420

cccucgcuuc ucugacuaca gagauacaga ucaauauuga aaucgagucg cguaagucau      480

acaaaaagau gcugaaggag augggugaag ucgccccuga guauagacac gacagcccag      540

auugugggau gauuauccuc ugcauagcag ccuuagugau uaccaaacug gcugcaggag      600

acaggagugg ccuuacggcc guuauccggc gcgcuaacaa uguguugaag aacgaaauga      660

aaagauacaa gggccugcua ccgaaagaua uugccaauuc cuucuaugag gucuuugaga      720

agcaucccca cuucaucgac guguuuguac acuucgggau cgcgcaaucu agcacuaggg      780

gagguucccg gguugaaggc auuuuugcag gacucuucau gaacgccuac ggggcuggcc      840

aggugaugcu gcgcuggggu guccuugcca aaucagugaa gaauauaaug cuggggcaug      900

caagugugca ggcugagaug gaacaggucg uugaggugua cgaauaugcc caaaaguugg      960

gaggcgaggc gggcuuuuac cacauccuca acaauccuaa agccagccug uuaucucuga     1020

cccaguuccc acauuuuucc ucaguagugc ucgggaacgc agcuggacuu gguauuaugg     1080

gcgaguaucg agggacaccc agaaaccagg accuguacga ugccgcuaag gccuaugcag     1140

aacaguugaa agagaaugga gucaucaacu acagcgugcu agaccugacu gccgaggaac     1200

ucgaagcuau aaagcaccaa cugaauccua aagauaacga cguugagcuu ugaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10371
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10371
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu gaacgacacc cugaacaagg      120

accagcugcu gagcagcagc aaguacacca uccagagaag caccggcgac agcaucgaca      180

cccccaacua cgacgugcag aagcacauca acaagcugug cggcaugcug cugaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucggcaugcu guacgccaug agcagacugg      300

gcagagagga caccaucaag auccugagag acgccggcua ccacgugaag gccaacggcg      360

uggacgugac cacccacaga caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccuggccag ccugaccacc gagauccaga ucaacaucga gaucgagagc agaaagagcu      480

acaagaagau gcugaaggag augggcgagg uggcccccga guacagacac gacagccccg      540

acugcggcau gaucauccug ugcaucgccg cccuggugau caccaagcug gccgccggcg      600

acagaagcgg ccugaccgcc gugaucagaa gagccaacaa cgugcugaag aacgagauga      660

agagauacaa gggccugcug cccaaggaca ucgccaacag cuucuacgag guguucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagagc agcaccagag      780

gcggcagcag aguggagggc aucuucgccg gccuguucau gaacgccuac ggcgccggcc      840

aggugaugcu gagauggggc gugcuggcca agagcgugaa gaacaucaug cugggccacg      900

ccagcgugca ggccgagaug gagcaggugg uggaggugua cgaguacgcc cagaagcugg      960

gcggcgaggc cggcuucuac cacauccuga acaaccccaa ggccagccug cugagccuga     1020

cccaguuccc ccacuucagc agcguggugc ugggcaacgc cgccggccug ggcaucaugg     1080

gcgaguacag aggcaccccc agaaaccagg accuguacga cgccgccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acagcgugcu ggaccugacc gccgaggagc     1200

uggaggccau caagcaccag cugaacccca aggacaacga cguggagcug ugaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10372
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10372
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cugaauaagg      120

aucagcuucu guccucuagc aaauacacaa uccaaagauc cacgggcgac ucuauugaua      180

cccccaacua ugacguccag aagcacauca auaaacucug cgggaugcug cuuauuacag      240

aggaugcuaa ccauaaguuc accggacuga ucggcaugcu cuacgccaug agccggcugg      300

ggcgcgaaga cacaauuaag auccugagag augcgggaua ucacguuaaa gcuaauggcg      360

uggacgugac cacacaucgg caggauauca acgggaagga gaugaaauuu gaaguccuca      420

cccuggccuc ccuuacgacc gagauucaga ucaauauuga aaucgagucu cgcaagagcu      480

acaaaaagau gcugaaggag augggagaag uggccccuga guauagacac gacuccccgg      540

auuguggcau gauuauccuc ugcauugcug cccugguuau cacaaaacuu gcugccggcg      600

accggagcgg gcugaccgcg gugauccgca gagccaacaa uguccucaag aacgaaauga      660

aacgguacaa gggacugcug cccaaagaua uugcuaauuc uuucuaugag guguuugaga      720

agcauccuca cuucaucgac guuuuugugc acuucggcau ugcccaaucc agcacacgcg      780

ggggaucuag agucgaaggc aucuuugcug gacucuucau gaacgccuac ggggcgggcc      840

aggugaugcu gcgguggggc gugcuugcca aauccgucaa gaauauuaug cuggggcaug      900

cuagcguuca ggccgagaug gaacaggugg uggaggucua cgaauaugcu caaaagcucg      960

gaggcgaggc cggguuuuac cacauccuga acaaucccaa agccucucuu cugucccuca     1020

cccaguuccc ucauuuuagc uccgugguuc ugggaaacgc ugcgggccug gggaucaugg     1080

gagaguaucg cggcacgccc agaaaccagg accucuacga ugccgcuaag gccuaugccg     1140

aacagcugaa agagaauggc gugauuaacu acucuguccu ugaccugaca gcugaggaac     1200

ucgaagccau caagcaccaa cugaauccua aagauaacga cguggagcuu ugaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10373
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10373
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaagca aagucaaauu aaacgacaca uuaaacaaag      120

accaacucuu aucaucauca aaauacacaa uacaaagaag caccggagac aguaucgaca      180

caccaaacua ugacguccaa aaacauauaa auaaauuaug cggcaugcuc uuaaucacag      240

aagacgccaa ccauaaauuu acaggauuaa uaggaauguu auaugcaaug ucacgacuag      300

guagagaaga cacaauaaaa auacuaagag acgcaggcua ucacguaaaa gcaaauggag      360

uagacguaac cacacacaga caagacauaa auggaaaaga aaugaaauuu gaaguauuaa      420

cacuagcauc acuaacaaca gaaauacaaa ucaacauaga aauagaauca agaaaaagcu      480

acaaaaaaau guuaaaagaa augggagaag ucgcaccaga auauagacau gauucaccag      540

acugcggaau gauaauacua ugcauagcag cccuaguaau uacaaaacua gcagcaggag      600

acagaagcgg auuaacagca guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga      660

aaagauauaa aggauuauua ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa      720

aacaccccca cuuuauagac gucuucguac acuucggaau agcccaauca uccacaagag      780

gaggaucaag agucgaagga auauucgcag gauuauucau gaacgcauau ggcgcaggac      840

aaguaaugcu aagaugggga guacuagcaa aauccgucaa aaacauaaug cuaggacacg      900

caucaguuca agcagaaaug gaacaaguag uagaaguaua cgaauacgcc caaaaacuag      960

gaggagaagc aggauucuac cacauacuaa auaauccaaa agcaucacua cuaagccuaa     1020

cccaauuucc ccacuucuca aguguaguau uaggaaaugc agcuggacua ggaauaaugg     1080

gagaauacag aggaacacca agaaaccaag acuuauacga cgcagcaaaa gcauacgcag     1140

agcaacuuaa agaaaacgga guaauaaacu auagcguacu agacuuaaca gcagaagaac     1200

uggaagcaau aaaacaucaa uuaaacccga aagacaauga cguagaauua uaaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10374
<211>  1532
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10374
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacucucga aaguaaaacu caacgacacc cucaacaaag      120

accaacuccu uuccagcucc aaauacacca uccaacgauc caccggagac uccaucgaca      180

cgcccaacua cgacguccag aaacacauca acaagcucug cggaaugcua cuaaucaccg      240

aggacgccaa ccacaaauuc acaggacuua uagggaugcu cuacgccaug ucccgccucg      300

gacgcgaaga cacaauaaaa auccuacgag acgccggcua ccacguaaag gcaaacggcg      360

ucgacgucac cacacacaga caagacauca acggaaagga aaugaaauuc gaaguccuca      420

cccucgccag ccuaaccacc gagauccaaa ucaacaucga aaucgaauca cgcaaauccu      480

acaagaaaau gcucaaagaa augggagaag ucgcccccga auaccgucac gacucgcccg      540

acugcggcau gauaauccua ugcaucgccg cacucgucau aaccaaacuc gccgccggug      600

accgaucagg acugacagca gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga      660

aacgcuacaa aggccuacuc cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa      720

aacacccaca cuucaucgac gucuucgucc acuucggcau cgcacaauca ucaaccagag      780

gcggcagccg cguugaaggc aucuucgcag gacucuuuau gaacgccuac ggcgccggcc      840

aagucaugcu ccgcuggggc guccuggcaa aaagcgucaa aaacaucaug cuaggccacg      900

cuagcgucca agccgaaaug gaacaagucg ucgaaguuua cgaguacgca caaaaacucg      960

gcggcgaagc aggcuucuac cacauccuaa acaaccccaa agccucccug cuaucacuca     1020

cccaauuccc ccacuucucc agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg     1080

gagaauaccg cgggacaccg cgcaaccaag accucuacga cgccgccaaa gccuacgccg     1140

aacaacucaa agaaaacggc gucauaaacu acucaguccu cgaccucacc gccgaagaac     1200

ucgaagccau caaacaccaa cucaacccaa aagacaacga cgucgaauua uaaggacuag     1260

uacuggcugc aucucccuuu ccucuguccu ccauccuucu cccaggaugg ugaaggggga     1320

ccugguaccc agugaucccc accccaggau ccuaaaucau gacuuaccug cuaauaaaaa     1380

cucauuggaa aagugagaag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1500

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1532


<210>  10375
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10375
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucuuagca aagucaaguu gaaugauaca cucaacaaag      120

aucaacuucu gucauccagc aaauacacca uccaacggag cacaggagau aguauugaua      180

cuccuaauua ugaugugcag aaacacauca auaaguuaug uggcauguua uuaaucacag      240

aagaugcuaa ucauaaauuc acuggguuaa uagguauguu auaugcgaug ucuagguuag      300

gaagagaaga caccauaaaa auacucagag augcgggaua ucauguaaaa gcaaauggag      360

uagauguaac aacacaucgu caagacauua auggaaaaga aaugaaauuu gaaguguuaa      420

cauuggcaag cuuaacaacu gaaauucaaa ucaacauuga gauagaaucu agaaaauccu      480

acaaaaaaau gcuaaaagaa augggagagg uagcuccaga auacaggcau gacucuccug      540

auugugggau gauaauauua uguauagcag cauuaguaau aacuaaauua gcagcagggg      600

acagaucugg ucuuacagcc gugauuagga gagcuaauaa uguccuaaaa aaugaaauga      660

aacguuacaa aggcuuacua cccaaggaca uagccaacag cuucuaugaa guguuugaaa      720

aacaucccca cuuuauagau guuuuuguuc auuuugguau agcacaaucu ucuaccagag      780

guggcaguag aguugaaggg auuuuugcag gauuguuuau gaaugccuau ggugcagggc      840

aagugauguu acggugggga gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug      900

cuagugugca agcagaaaug gaacaaguug uugagguuua ugaauaugcc caaaaauugg      960

guggugaagc aggauucuac cauauauuga acaacccaaa agcaucauua uuaucuuuga     1020

cucaauuucc ucacuucucc aguguaguau uaggcaaugc ugcuggccua ggcauaaugg     1080

gagaguacag agguacaccg aggaaucaag aucuauauga ugcagcaaag gcauaugcug     1140

aacaacucaa agaaaauggu gugauuaacu acaguguacu agacuugaca gcagaagaac     1200

uagaggcuau caaacaucag cuuaauccaa aagauaauga uguagagcuu ugaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10376
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10376
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu caacgacacc cugaacaagg      120

accagcugcu cuccagcucc aaguacacca uccagcgcag caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcugug cgggaugcug cucaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucgggaugcu guacgcgaug agccggcucg      300

gccgcgagga cacgaucaag auccugcggg acgccgggua ccacgugaag gccaacggcg      360

uggacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccucgccuc ccugacgacc gagauccaga ucaacaucga gaucgagagc cggaaguccu      480

acaagaagau gcugaaggag augggggagg uggccccgga guaccgccac gacagccccg      540

acugcggcau gaucauccuc ugcaucgcgg cccuggucau caccaagcug gccgccgggg      600

accgguccgg ccucaccgcg gugauccgcc gggccaacaa cgugcugaag aacgagauga      660

agcgcuacaa ggggcugcuc cccaaggaca ucgccaacag cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagucc agcacgcggg      780

gcgggucccg cgucgagggc aucuucgccg ggcuguucau gaacgcguac ggcgccggcc      840

aggugaugcu gcgguggggc gugcucgcca agagcgucaa gaacaucaug cuggggcacg      900

ccuccgugca ggccgagaug gagcaggucg uggaggugua cgaguacgcg cagaagcucg      960

ggggcgaggc cggguucuac cacauccuga acaacccgaa ggccagccug cugucccuca     1020

cccaguuccc ccacuucagc agcguggucc ugggcaacgc cgccggccug gggaucaugg     1080

gcgaguaccg cgggacgccc cggaaccagg accucuacga cgcggccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acuccgugcu ggaccucacc gccgaggagc     1200

uggaggcgau caagcaccag cugaacccca aggacaacga cgucgagcuc ugaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10377
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10377
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccucucca aggucaagcu caacgacacc cucaacaagg      120

accagcuccu cuccuccucc aaguacacca uccagcgcuc caccggcgac uccaucgaca      180

cccccaacua cgacguccag aagcacauca acaagcucug cggcaugcuc cucaucaccg      240

aggacgccaa ccacaaguuc accggccuca ucggcaugcu cuacgccaug ucccgccucg      300

gccgcgagga caccaucaag auccuccgcg acgccggcua ccacgucaag gccaacggcg      360

ucgacgucac cacccaccgc caggacauca acggcaagga gaugaaguuc gagguccuca      420

cccucgccuc ccucaccacc gagauccaga ucaacaucga gaucgagucc cgcaaguccu      480

acaagaagau gcucaaggag augggcgagg ucgcccccga guaccgccac gacucccccg      540

acugcggcau gaucauccuc ugcaucgccg cccucgucau caccaagcuc gccgccggcg      600

accgcuccgg ccucaccgcc gucauccgcc gcgccaacaa cguccucaag aacgagauga      660

agcgcuacaa gggccuccuc cccaaggaca ucgccaacuc cuucuacgag gucuucgaga      720

agcaccccca cuucaucgac gucuucgucc acuucggcau cgcccagucc uccacccgcg      780

gcggcucccg cgucgagggc aucuucgccg gccucuucau gaacgccuac ggcgccggcc      840

aggucaugcu ccgcuggggc guccucgcca aguccgucaa gaacaucaug cucggccacg      900

ccuccgucca ggccgagaug gagcaggucg ucgaggucua cgaguacgcc cagaagcucg      960

gcggcgaggc cggcuucuac cacauccuca acaaccccaa ggccucccuc cucucccuca     1020

cccaguuccc ccacuucucc uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg     1080

gcgaguaccg cggcaccccc cgcaaccagg accucuacga cgccgccaag gccuacgccg     1140

agcagcucaa ggagaacggc gucaucaacu acuccguccu cgaccucacc gccgaggagc     1200

ucgaggccau caagcaccag cucaacccca aggacaacga cgucgagcuc ugaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10378
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10378
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cuuaauaagg      120

aucagcuguu guccucuuca aaauacacaa uccaaagaag uacuggcgac agcauugaua      180

cgcccaacua ugacguccag aagcacauaa auaaauuaug cgggaugcug cuaaucaccg      240

aggaugcuaa ccauaaguuc acaggacuca uugguaugcu guacgcaaug uccaggcuug      300

gccgggaaga cacuaucaag auucugcgcg augccgggua ucacguuaaa gcgaauggag      360

uggacguaac cacacaucga caggauauca acggcaagga gaugaaauuu gaaguguuga      420

cccucgcuuc ucugacuaca gagauacaga ucaauauuga aaucgagucg cguaagucau      480

acaaaaagau gcugaaggag augggugaag ucgccccuga guauagacac gacagcccag      540

auugugggau gauuauccuc ugcauagcag ccuuagugau uaccaaacug gcugcaggag      600

acaggagugg ccuuacggcc guuauccggc gcgcuaacaa uguguugaag aacgaaauga      660

aaagauacaa gggccugcua ccgaaagaua uugccaauuc cuucuaugag gucuuugaga      720

agcaucccca cuucaucgac guguuuguac acuucgggau cgcgcaaucu agcacuaggg      780

gagguucccg gguugaaggc auuuuugcag gacucuucau gaacgccuac ggggcuggcc      840

aggugaugcu gcgcuggggu guccuugcca aaucagugaa gaauauaaug cuggggcaug      900

caagugugca ggcugagaug gaacaggucg uugaggugua cgaauaugcc caaaaguugg      960

gaggcgaggc gggcuuuuac cacauccuca acaauccuaa agccagccug uuaucucuga     1020

cccaguuccc acauuuuucc ucaguagugc ucgggaacgc agcuggacuu gguauuaugg     1080

gcgaguaucg agggacaccc agaaaccagg accuguacga ugccgcuaag gccuaugcag     1140

aacaguugaa agagaaugga gucaucaacu acagcgugcu agaccugacu gccgaggaac     1200

ucgaagcuau aaagcaccaa cugaauccua aagauaacga cguugagcuu ugaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10379
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10379
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaagcu gaacgacacc cugaacaagg      120

accagcugcu gagcagcagc aaguacacca uccagagaag caccggcgac agcaucgaca      180

cccccaacua cgacgugcag aagcacauca acaagcugug cggcaugcug cugaucaccg      240

aggacgccaa ccacaaguuc accggccuga ucggcaugcu guacgccaug agcagacugg      300

gcagagagga caccaucaag auccugagag acgccggcua ccacgugaag gccaacggcg      360

uggacgugac cacccacaga caggacauca acggcaagga gaugaaguuc gaggugcuga      420

cccuggccag ccugaccacc gagauccaga ucaacaucga gaucgagagc agaaagagcu      480

acaagaagau gcugaaggag augggcgagg uggcccccga guacagacac gacagccccg      540

acugcggcau gaucauccug ugcaucgccg cccuggugau caccaagcug gccgccggcg      600

acagaagcgg ccugaccgcc gugaucagaa gagccaacaa cgugcugaag aacgagauga      660

agagauacaa gggccugcug cccaaggaca ucgccaacag cuucuacgag guguucgaga      720

agcaccccca cuucaucgac guguucgugc acuucggcau cgcccagagc agcaccagag      780

gcggcagcag aguggagggc aucuucgccg gccuguucau gaacgccuac ggcgccggcc      840

aggugaugcu gagauggggc gugcuggcca agagcgugaa gaacaucaug cugggccacg      900

ccagcgugca ggccgagaug gagcaggugg uggaggugua cgaguacgcc cagaagcugg      960

gcggcgaggc cggcuucuac cacauccuga acaaccccaa ggccagccug cugagccuga     1020

cccaguuccc ccacuucagc agcguggugc ugggcaacgc cgccggccug ggcaucaugg     1080

gcgaguacag aggcaccccc agaaaccagg accuguacga cgccgccaag gccuacgccg     1140

agcagcugaa ggagaacggc gugaucaacu acagcgugcu ggaccugacc gccgaggagc     1200

uggaggccau caagcaccag cugaacccca aggacaacga cguggagcug ugaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10380
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10380
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagca aggugaaacu caacgacacc cugaauaagg      120

aucagcuucu guccucuagc aaauacacaa uccaaagauc cacgggcgac ucuauugaua      180

cccccaacua ugacguccag aagcacauca auaaacucug cgggaugcug cuuauuacag      240

aggaugcuaa ccauaaguuc accggacuga ucggcaugcu cuacgccaug agccggcugg      300

ggcgcgaaga cacaauuaag auccugagag augcgggaua ucacguuaaa gcuaauggcg      360

uggacgugac cacacaucgg caggauauca acgggaagga gaugaaauuu gaaguccuca      420

cccuggccuc ccuuacgacc gagauucaga ucaauauuga aaucgagucu cgcaagagcu      480

acaaaaagau gcugaaggag augggagaag uggccccuga guauagacac gacuccccgg      540

auuguggcau gauuauccuc ugcauugcug cccugguuau cacaaaacuu gcugccggcg      600

accggagcgg gcugaccgcg gugauccgca gagccaacaa uguccucaag aacgaaauga      660

aacgguacaa gggacugcug cccaaagaua uugcuaauuc uuucuaugag guguuugaga      720

agcauccuca cuucaucgac guuuuugugc acuucggcau ugcccaaucc agcacacgcg      780

ggggaucuag agucgaaggc aucuuugcug gacucuucau gaacgccuac ggggcgggcc      840

aggugaugcu gcgguggggc gugcuugcca aauccgucaa gaauauuaug cuggggcaug      900

cuagcguuca ggccgagaug gaacaggugg uggaggucua cgaauaugcu caaaagcucg      960

gaggcgaggc cggguuuuac cacauccuga acaaucccaa agccucucuu cugucccuca     1020

cccaguuccc ucauuuuagc uccgugguuc ugggaaacgc ugcgggccug gggaucaugg     1080

gagaguaucg cggcacgccc agaaaccagg accucuacga ugccgcuaag gccuaugccg     1140

aacagcugaa agagaauggc gugauuaacu acucuguccu ugaccugaca gcugaggaac     1200

ucgaagccau caagcaccaa cugaauccua aagauaacga cguggagcuu ugaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10381
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10381
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaagca aagucaaauu aaacgacaca uuaaacaaag      120

accaacucuu aucaucauca aaauacacaa uacaaagaag caccggagac aguaucgaca      180

caccaaacua ugacguccaa aaacauauaa auaaauuaug cggcaugcuc uuaaucacag      240

aagacgccaa ccauaaauuu acaggauuaa uaggaauguu auaugcaaug ucacgacuag      300

guagagaaga cacaauaaaa auacuaagag acgcaggcua ucacguaaaa gcaaauggag      360

uagacguaac cacacacaga caagacauaa auggaaaaga aaugaaauuu gaaguauuaa      420

cacuagcauc acuaacaaca gaaauacaaa ucaacauaga aauagaauca agaaaaagcu      480

acaaaaaaau guuaaaagaa augggagaag ucgcaccaga auauagacau gauucaccag      540

acugcggaau gauaauacua ugcauagcag cccuaguaau uacaaaacua gcagcaggag      600

acagaagcgg auuaacagca guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga      660

aaagauauaa aggauuauua ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa      720

aacaccccca cuuuauagac gucuucguac acuucggaau agcccaauca uccacaagag      780

gaggaucaag agucgaagga auauucgcag gauuauucau gaacgcauau ggcgcaggac      840

aaguaaugcu aagaugggga guacuagcaa aauccgucaa aaacauaaug cuaggacacg      900

caucaguuca agcagaaaug gaacaaguag uagaaguaua cgaauacgcc caaaaacuag      960

gaggagaagc aggauucuac cacauacuaa auaauccaaa agcaucacua cuaagccuaa     1020

cccaauuucc ccacuucuca aguguaguau uaggaaaugc agcuggacua ggaauaaugg     1080

gagaauacag aggaacacca agaaaccaag acuuauacga cgcagcaaaa gcauacgcag     1140

agcaacuuaa agaaaacgga guaauaaacu auagcguacu agacuuaaca gcagaagaac     1200

uggaagcaau aaaacaucaa uuaaacccga aagacaauga cguagaauua uaaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10382
<211>  1748
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10382
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacucucga aaguaaaacu caacgacacc cucaacaaag      120

accaacuccu uuccagcucc aaauacacca uccaacgauc caccggagac uccaucgaca      180

cgcccaacua cgacguccag aaacacauca acaagcucug cggaaugcua cuaaucaccg      240

aggacgccaa ccacaaauuc acaggacuua uagggaugcu cuacgccaug ucccgccucg      300

gacgcgaaga cacaauaaaa auccuacgag acgccggcua ccacguaaag gcaaacggcg      360

ucgacgucac cacacacaga caagacauca acggaaagga aaugaaauuc gaaguccuca      420

cccucgccag ccuaaccacc gagauccaaa ucaacaucga aaucgaauca cgcaaauccu      480

acaagaaaau gcucaaagaa augggagaag ucgcccccga auaccgucac gacucgcccg      540

acugcggcau gauaauccua ugcaucgccg cacucgucau aaccaaacuc gccgccggug      600

accgaucagg acugacagca gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga      660

aacgcuacaa aggccuacuc cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa      720

aacacccaca cuucaucgac gucuucgucc acuucggcau cgcacaauca ucaaccagag      780

gcggcagccg cguugaaggc aucuucgcag gacucuuuau gaacgccuac ggcgccggcc      840

aagucaugcu ccgcuggggc guccuggcaa aaagcgucaa aaacaucaug cuaggccacg      900

cuagcgucca agccgaaaug gaacaagucg ucgaaguuua cgaguacgca caaaaacucg      960

gcggcgaagc aggcuucuac cacauccuaa acaaccccaa agccucccug cuaucacuca     1020

cccaauuccc ccacuucucc agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg     1080

gagaauaccg cgggacaccg cgcaaccaag accucuacga cgccgccaaa gccuacgccg     1140

aacaacucaa agaaaacggc gucauaaacu acucaguccu cgaccucacc gccgaagaac     1200

ucgaagccau caaacaccaa cucaacccaa aagacaacga cgucgaauua uaaggacuag     1260

ugaagggaac acccaaauuu aauucagccu uaagcacaau uaauuaagag ugaaacguaa     1320

uuguacaagc aguuggucac ccaccauagg gcaugaucaa caccgcaacc uuuccuuuuu     1380

cccccaguga uucugaaaaa ccccucuucc cuucagcuug cuuagauguu ccaaauuuag     1440

uaagcuuaag gcggccuaca gaagaaaaag aaaaaaaagg ccacaaaagu ucccucucac     1500

uuucaguaaa uaaaauaaaa gcagcaacag aaauaaagaa auaaaugaaa uucaaaauga     1560

aauaaauauu guguugugca gcauuaaaaa aucaauaaaa auuaaaaaug agcaagaucu     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1740

ccagaauu                                                              1748


<210>  10383
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10383
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcucuuag caaagucaag uugaaugaua cacucaacaa agaucaacuu      120

cugucaucca gcaaauacac cauccaacgg agcacaggag auaguauuga uacuccuaau      180

uaugaugugc agaaacacau caauaaguua uguggcaugu uauuaaucac agaagaugcu      240

aaucauaaau ucacuggguu aauagguaug uuauaugcga ugucuagguu aggaagagaa      300

gacaccauaa aaauacucag agaugcggga uaucauguaa aagcaaaugg aguagaugua      360

acaacacauc gucaagacau uaauggaaaa gaaaugaaau uugaaguguu aacauuggca      420

agcuuaacaa cugaaauuca aaucaacauu gagauagaau cuagaaaauc cuacaaaaaa      480

augcuaaaag aaaugggaga gguagcucca gaauacaggc augacucucc ugauuguggg      540

augauaauau uauguauagc agcauuagua auaacuaaau uagcagcagg ggacagaucu      600

ggucuuacag ccgugauuag gagagcuaau aauguccuaa aaaaugaaau gaaacguuac      660

aaaggcuuac uacccaagga cauagccaac agcuucuaug aaguguuuga aaaacauccc      720

cacuuuauag auguuuuugu ucauuuuggu auagcacaau cuucuaccag agguggcagu      780

agaguugaag ggauuuuugc aggauuguuu augaaugccu auggugcagg gcaagugaug      840

uuacgguggg gagucuuagc aaaaucaguu aaaaauauua uguuaggaca ugcuagugug      900

caagcagaaa uggaacaagu uguugagguu uaugaauaug cccaaaaauu ggguggugaa      960

gcaggauucu accauauauu gaacaaccca aaagcaucau uauuaucuuu gacucaauuu     1020

ccucacuucu ccaguguagu auuaggcaau gcugcuggcc uaggcauaau gggagaguac     1080

agagguacac cgaggaauca agaucuauau gaugcagcaa aggcauaugc ugaacaacuc     1140

aaagaaaaug gugugauuaa cuacagugua cuagacuuga cagcagaaga acuagaggcu     1200

aucaaacauc agcuuaaucc aaaagauaau gauguagagc uuugaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10384
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10384
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cucaacgaca cccugaacaa ggaccagcug      120

cucuccagcu ccaaguacac cauccagcgc agcaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcug ugcgggaugc ugcucaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucgggaug cuguacgcga ugagccggcu cggccgcgag      300

gacacgauca agauccugcg ggacgccggg uaccacguga aggccaacgg cguggacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgaggugcu gacccucgcc      420

ucccugacga ccgagaucca gaucaacauc gagaucgaga gccggaaguc cuacaagaag      480

augcugaagg agauggggga gguggccccg gaguaccgcc acgacagccc cgacugcggc      540

augaucaucc ucugcaucgc ggcccugguc aucaccaagc uggccgccgg ggaccggucc      600

ggccucaccg cggugauccg ccgggccaac aacgugcuga agaacgagau gaagcgcuac      660

aaggggcugc uccccaagga caucgccaac agcuucuacg aggucuucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccagu ccagcacgcg gggcgggucc      780

cgcgucgagg gcaucuucgc cgggcuguuc augaacgcgu acggcgccgg ccaggugaug      840

cugcgguggg gcgugcucgc caagagcguc aagaacauca ugcuggggca cgccuccgug      900

caggccgaga uggagcaggu cguggaggug uacgaguacg cgcagaagcu cgggggcgag      960

gccggguucu accacauccu gaacaacccg aaggccagcc ugcugucccu cacccaguuc     1020

ccccacuuca gcagcguggu ccugggcaac gccgccggcc uggggaucau gggcgaguac     1080

cgcgggacgc cccggaacca ggaccucuac gacgcggcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacuccgug cuggaccuca ccgccgagga gcuggaggcg     1200

aucaagcacc agcugaaccc caaggacaac gacgucgagc ucugaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10385
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10385
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccucuc caaggucaag cucaacgaca cccucaacaa ggaccagcuc      120

cucuccuccu ccaaguacac cauccagcgc uccaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcuc ugcggcaugc uccucaucac cgaggacgcc      240

aaccacaagu ucaccggccu caucggcaug cucuacgcca ugucccgccu cggccgcgag      300

gacaccauca agauccuccg cgacgccggc uaccacguca aggccaacgg cgucgacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgagguccu cacccucgcc      420

ucccucacca ccgagaucca gaucaacauc gagaucgagu cccgcaaguc cuacaagaag      480

augcucaagg agaugggcga ggucgccccc gaguaccgcc acgacucccc cgacugcggc      540

augaucaucc ucugcaucgc cgcccucguc aucaccaagc ucgccgccgg cgaccgcucc      600

ggccucaccg ccgucauccg ccgcgccaac aacguccuca agaacgagau gaagcgcuac      660

aagggccucc uccccaagga caucgccaac uccuucuacg aggucuucga gaagcacccc      720

cacuucaucg acgucuucgu ccacuucggc aucgcccagu ccuccacccg cggcggcucc      780

cgcgucgagg gcaucuucgc cggccucuuc augaacgccu acggcgccgg ccaggucaug      840

cuccgcuggg gcguccucgc caaguccguc aagaacauca ugcucggcca cgccuccguc      900

caggccgaga uggagcaggu cgucgagguc uacgaguacg cccagaagcu cggcggcgag      960

gccggcuucu accacauccu caacaacccc aaggccuccc uccucucccu cacccaguuc     1020

ccccacuucu ccuccgucgu ccucggcaac gccgccggcc ucggcaucau gggcgaguac     1080

cgcggcaccc cccgcaacca ggaccucuac gacgccgcca aggccuacgc cgagcagcuc     1140

aaggagaacg gcgucaucaa cuacuccguc cucgaccuca ccgccgagga gcucgaggcc     1200

aucaagcacc agcucaaccc caaggacaac gacgucgagc ucugaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10386
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10386
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccuuaauaa ggaucagcug      120

uuguccucuu caaaauacac aauccaaaga aguacuggcg acagcauuga uacgcccaac      180

uaugacgucc agaagcacau aaauaaauua ugcgggaugc ugcuaaucac cgaggaugcu      240

aaccauaagu ucacaggacu cauugguaug cuguacgcaa uguccaggcu uggccgggaa      300

gacacuauca agauucugcg cgaugccggg uaucacguua aagcgaaugg aguggacgua      360

accacacauc gacaggauau caacggcaag gagaugaaau uugaaguguu gacccucgcu      420

ucucugacua cagagauaca gaucaauauu gaaaucgagu cgcguaaguc auacaaaaag      480

augcugaagg agauggguga agucgccccu gaguauagac acgacagccc agauuguggg      540

augauuaucc ucugcauagc agccuuagug auuaccaaac uggcugcagg agacaggagu      600

ggccuuacgg ccguuauccg gcgcgcuaac aauguguuga agaacgaaau gaaaagauac      660

aagggccugc uaccgaaaga uauugccaau uccuucuaug aggucuuuga gaagcauccc      720

cacuucaucg acguguuugu acacuucggg aucgcgcaau cuagcacuag gggagguucc      780

cggguugaag gcauuuuugc aggacucuuc augaacgccu acggggcugg ccaggugaug      840

cugcgcuggg guguccuugc caaaucagug aagaauauaa ugcuggggca ugcaagugug      900

caggcugaga uggaacaggu cguugaggug uacgaauaug cccaaaaguu gggaggcgag      960

gcgggcuuuu accacauccu caacaauccu aaagccagcc uguuaucucu gacccaguuc     1020

ccacauuuuu ccucaguagu gcucgggaac gcagcuggac uugguauuau gggcgaguau     1080

cgagggacac ccagaaacca ggaccuguac gaugccgcua aggccuaugc agaacaguug     1140

aaagagaaug gagucaucaa cuacagcgug cuagaccuga cugccgagga acucgaagcu     1200

auaaagcacc aacugaaucc uaaagauaac gacguugagc uuugaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10387
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10387
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cugaacgaca cccugaacaa ggaccagcug      120

cugagcagca gcaaguacac cauccagaga agcaccggcg acagcaucga cacccccaac      180

uacgacgugc agaagcacau caacaagcug ugcggcaugc ugcugaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucggcaug cuguacgcca ugagcagacu gggcagagag      300

gacaccauca agauccugag agacgccggc uaccacguga aggccaacgg cguggacgug      360

accacccaca gacaggacau caacggcaag gagaugaagu ucgaggugcu gacccuggcc      420

agccugacca ccgagaucca gaucaacauc gagaucgaga gcagaaagag cuacaagaag      480

augcugaagg agaugggcga gguggccccc gaguacagac acgacagccc cgacugcggc      540

augaucaucc ugugcaucgc cgcccuggug aucaccaagc uggccgccgg cgacagaagc      600

ggccugaccg ccgugaucag aagagccaac aacgugcuga agaacgagau gaagagauac      660

aagggccugc ugcccaagga caucgccaac agcuucuacg agguguucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccaga gcagcaccag aggcggcagc      780

agaguggagg gcaucuucgc cggccuguuc augaacgccu acggcgccgg ccaggugaug      840

cugagauggg gcgugcuggc caagagcgug aagaacauca ugcugggcca cgccagcgug      900

caggccgaga uggagcaggu gguggaggug uacgaguacg cccagaagcu gggcggcgag      960

gccggcuucu accacauccu gaacaacccc aaggccagcc ugcugagccu gacccaguuc     1020

ccccacuuca gcagcguggu gcugggcaac gccgccggcc ugggcaucau gggcgaguac     1080

agaggcaccc ccagaaacca ggaccuguac gacgccgcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacagcgug cuggaccuga ccgccgagga gcuggaggcc     1200

aucaagcacc agcugaaccc caaggacaac gacguggagc ugugaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10388
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10388
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccugaauaa ggaucagcuu      120

cuguccucua gcaaauacac aauccaaaga uccacgggcg acucuauuga uacccccaac      180

uaugacgucc agaagcacau caauaaacuc ugcgggaugc ugcuuauuac agaggaugcu      240

aaccauaagu ucaccggacu gaucggcaug cucuacgcca ugagccggcu ggggcgcgaa      300

gacacaauua agauccugag agaugcggga uaucacguua aagcuaaugg cguggacgug      360

accacacauc ggcaggauau caacgggaag gagaugaaau uugaaguccu cacccuggcc      420

ucccuuacga ccgagauuca gaucaauauu gaaaucgagu cucgcaagag cuacaaaaag      480

augcugaagg agaugggaga aguggccccu gaguauagac acgacucccc ggauuguggc      540

augauuaucc ucugcauugc ugcccugguu aucacaaaac uugcugccgg cgaccggagc      600

gggcugaccg cggugauccg cagagccaac aauguccuca agaacgaaau gaaacgguac      660

aagggacugc ugcccaaaga uauugcuaau ucuuucuaug agguguuuga gaagcauccu      720

cacuucaucg acguuuuugu gcacuucggc auugcccaau ccagcacacg cgggggaucu      780

agagucgaag gcaucuuugc uggacucuuc augaacgccu acggggcggg ccaggugaug      840

cugcgguggg gcgugcuugc caaauccguc aagaauauua ugcuggggca ugcuagcguu      900

caggccgaga uggaacaggu gguggagguc uacgaauaug cucaaaagcu cggaggcgag      960

gccggguuuu accacauccu gaacaauccc aaagccucuc uucugucccu cacccaguuc     1020

ccucauuuua gcuccguggu ucugggaaac gcugcgggcc uggggaucau gggagaguau     1080

cgcggcacgc ccagaaacca ggaccucuac gaugccgcua aggccuaugc cgaacagcug     1140

aaagagaaug gcgugauuaa cuacucuguc cuugaccuga cagcugagga acucgaagcc     1200

aucaagcacc aacugaaucc uaaagauaac gacguggagc uuugaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10389
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10389
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacuaag caaagucaaa uuaaacgaca cauuaaacaa agaccaacuc      120

uuaucaucau caaaauacac aauacaaaga agcaccggag acaguaucga cacaccaaac      180

uaugacgucc aaaaacauau aaauaaauua ugcggcaugc ucuuaaucac agaagacgcc      240

aaccauaaau uuacaggauu aauaggaaug uuauaugcaa ugucacgacu agguagagaa      300

gacacaauaa aaauacuaag agacgcaggc uaucacguaa aagcaaaugg aguagacgua      360

accacacaca gacaagacau aaauggaaaa gaaaugaaau uugaaguauu aacacuagca      420

ucacuaacaa cagaaauaca aaucaacaua gaaauagaau caagaaaaag cuacaaaaaa      480

auguuaaaag aaaugggaga agucgcacca gaauauagac augauucacc agacugcgga      540

augauaauac uaugcauagc agcccuagua auuacaaaac uagcagcagg agacagaagc      600

ggauuaacag caguaauaag aagagcaaac aacguacuaa aaaacgaaau gaaaagauau      660

aaaggauuau uaccaaaaga cauagcaaac ucauucuaug aaguauucga aaaacacccc      720

cacuuuauag acgucuucgu acacuucgga auagcccaau cauccacaag aggaggauca      780

agagucgaag gaauauucgc aggauuauuc augaacgcau auggcgcagg acaaguaaug      840

cuaagauggg gaguacuagc aaaauccguc aaaaacauaa ugcuaggaca cgcaucaguu      900

caagcagaaa uggaacaagu aguagaagua uacgaauacg cccaaaaacu aggaggagaa      960

gcaggauucu accacauacu aaauaaucca aaagcaucac uacuaagccu aacccaauuu     1020

ccccacuucu caaguguagu auuaggaaau gcagcuggac uaggaauaau gggagaauac     1080

agaggaacac caagaaacca agacuuauac gacgcagcaa aagcauacgc agagcaacuu     1140

aaagaaaacg gaguaauaaa cuauagcgua cuagacuuaa cagcagaaga acuggaagca     1200

auaaaacauc aauuaaaccc gaaagacaau gacguagaau uauaaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10390
<211>  1524
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10390
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacucuc gaaaguaaaa cucaacgaca cccucaacaa agaccaacuc      120

cuuuccagcu ccaaauacac cauccaacga uccaccggag acuccaucga cacgcccaac      180

uacgacgucc agaaacacau caacaagcuc ugcggaaugc uacuaaucac cgaggacgcc      240

aaccacaaau ucacaggacu uauagggaug cucuacgcca ugucccgccu cggacgcgaa      300

gacacaauaa aaauccuacg agacgccggc uaccacguaa aggcaaacgg cgucgacguc      360

accacacaca gacaagacau caacggaaag gaaaugaaau ucgaaguccu cacccucgcc      420

agccuaacca ccgagaucca aaucaacauc gaaaucgaau cacgcaaauc cuacaagaaa      480

augcucaaag aaaugggaga agucgccccc gaauaccguc acgacucgcc cgacugcggc      540

augauaaucc uaugcaucgc cgcacucguc auaaccaaac ucgccgccgg ugaccgauca      600

ggacugacag cagucauccg ccgagcaaac aacgugcuca aaaacgaaau gaaacgcuac      660

aaaggccuac uccccaaaga caucgccaac uccuucuacg aagucuucga aaaacaccca      720

cacuucaucg acgucuucgu ccacuucggc aucgcacaau caucaaccag aggcggcagc      780

cgcguugaag gcaucuucgc aggacucuuu augaacgccu acggcgccgg ccaagucaug      840

cuccgcuggg gcguccuggc aaaaagcguc aaaaacauca ugcuaggcca cgcuagcguc      900

caagccgaaa uggaacaagu cgucgaaguu uacgaguacg cacaaaaacu cggcggcgaa      960

gcaggcuucu accacauccu aaacaacccc aaagccuccc ugcuaucacu cacccaauuc     1020

ccccacuucu ccagcgucgu ccucggcaac gccgcaggac uaggcaucau gggagaauac     1080

cgcgggacac cgcgcaacca agaccucuac gacgccgcca aagccuacgc cgaacaacuc     1140

aaagaaaacg gcgucauaaa cuacucaguc cucgaccuca ccgccgaaga acucgaagcc     1200

aucaaacacc aacucaaccc aaaagacaac gacgucgaau uauaaggacu aguacuggcu     1260

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac     1320

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg     1380

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1500

gcucuuuuca gagccaccag aauu                                            1524


<210>  10391
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10391
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcucuuag caaagucaag uugaaugaua cacucaacaa agaucaacuu      120

cugucaucca gcaaauacac cauccaacgg agcacaggag auaguauuga uacuccuaau      180

uaugaugugc agaaacacau caauaaguua uguggcaugu uauuaaucac agaagaugcu      240

aaucauaaau ucacuggguu aauagguaug uuauaugcga ugucuagguu aggaagagaa      300

gacaccauaa aaauacucag agaugcggga uaucauguaa aagcaaaugg aguagaugua      360

acaacacauc gucaagacau uaauggaaaa gaaaugaaau uugaaguguu aacauuggca      420

agcuuaacaa cugaaauuca aaucaacauu gagauagaau cuagaaaauc cuacaaaaaa      480

augcuaaaag aaaugggaga gguagcucca gaauacaggc augacucucc ugauuguggg      540

augauaauau uauguauagc agcauuagua auaacuaaau uagcagcagg ggacagaucu      600

ggucuuacag ccgugauuag gagagcuaau aauguccuaa aaaaugaaau gaaacguuac      660

aaaggcuuac uacccaagga cauagccaac agcuucuaug aaguguuuga aaaacauccc      720

cacuuuauag auguuuuugu ucauuuuggu auagcacaau cuucuaccag agguggcagu      780

agaguugaag ggauuuuugc aggauuguuu augaaugccu auggugcagg gcaagugaug      840

uuacgguggg gagucuuagc aaaaucaguu aaaaauauua uguuaggaca ugcuagugug      900

caagcagaaa uggaacaagu uguugagguu uaugaauaug cccaaaaauu ggguggugaa      960

gcaggauucu accauauauu gaacaaccca aaagcaucau uauuaucuuu gacucaauuu     1020

ccucacuucu ccaguguagu auuaggcaau gcugcuggcc uaggcauaau gggagaguac     1080

agagguacac cgaggaauca agaucuauau gaugcagcaa aggcauaugc ugaacaacuc     1140

aaagaaaaug gugugauuaa cuacagugua cuagacuuga cagcagaaga acuagaggcu     1200

aucaaacauc agcuuaaucc aaaagauaau gauguagagc uuugaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10392
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10392
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cucaacgaca cccugaacaa ggaccagcug      120

cucuccagcu ccaaguacac cauccagcgc agcaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcug ugcgggaugc ugcucaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucgggaug cuguacgcga ugagccggcu cggccgcgag      300

gacacgauca agauccugcg ggacgccggg uaccacguga aggccaacgg cguggacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgaggugcu gacccucgcc      420

ucccugacga ccgagaucca gaucaacauc gagaucgaga gccggaaguc cuacaagaag      480

augcugaagg agauggggga gguggccccg gaguaccgcc acgacagccc cgacugcggc      540

augaucaucc ucugcaucgc ggcccugguc aucaccaagc uggccgccgg ggaccggucc      600

ggccucaccg cggugauccg ccgggccaac aacgugcuga agaacgagau gaagcgcuac      660

aaggggcugc uccccaagga caucgccaac agcuucuacg aggucuucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccagu ccagcacgcg gggcgggucc      780

cgcgucgagg gcaucuucgc cgggcuguuc augaacgcgu acggcgccgg ccaggugaug      840

cugcgguggg gcgugcucgc caagagcguc aagaacauca ugcuggggca cgccuccgug      900

caggccgaga uggagcaggu cguggaggug uacgaguacg cgcagaagcu cgggggcgag      960

gccggguucu accacauccu gaacaacccg aaggccagcc ugcugucccu cacccaguuc     1020

ccccacuuca gcagcguggu ccugggcaac gccgccggcc uggggaucau gggcgaguac     1080

cgcgggacgc cccggaacca ggaccucuac gacgcggcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacuccgug cuggaccuca ccgccgagga gcuggaggcg     1200

aucaagcacc agcugaaccc caaggacaac gacgucgagc ucugaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10393
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10393
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccucuc caaggucaag cucaacgaca cccucaacaa ggaccagcuc      120

cucuccuccu ccaaguacac cauccagcgc uccaccggcg acuccaucga cacccccaac      180

uacgacgucc agaagcacau caacaagcuc ugcggcaugc uccucaucac cgaggacgcc      240

aaccacaagu ucaccggccu caucggcaug cucuacgcca ugucccgccu cggccgcgag      300

gacaccauca agauccuccg cgacgccggc uaccacguca aggccaacgg cgucgacguc      360

accacccacc gccaggacau caacggcaag gagaugaagu ucgagguccu cacccucgcc      420

ucccucacca ccgagaucca gaucaacauc gagaucgagu cccgcaaguc cuacaagaag      480

augcucaagg agaugggcga ggucgccccc gaguaccgcc acgacucccc cgacugcggc      540

augaucaucc ucugcaucgc cgcccucguc aucaccaagc ucgccgccgg cgaccgcucc      600

ggccucaccg ccgucauccg ccgcgccaac aacguccuca agaacgagau gaagcgcuac      660

aagggccucc uccccaagga caucgccaac uccuucuacg aggucuucga gaagcacccc      720

cacuucaucg acgucuucgu ccacuucggc aucgcccagu ccuccacccg cggcggcucc      780

cgcgucgagg gcaucuucgc cggccucuuc augaacgccu acggcgccgg ccaggucaug      840

cuccgcuggg gcguccucgc caaguccguc aagaacauca ugcucggcca cgccuccguc      900

caggccgaga uggagcaggu cgucgagguc uacgaguacg cccagaagcu cggcggcgag      960

gccggcuucu accacauccu caacaacccc aaggccuccc uccucucccu cacccaguuc     1020

ccccacuucu ccuccgucgu ccucggcaac gccgccggcc ucggcaucau gggcgaguac     1080

cgcggcaccc cccgcaacca ggaccucuac gacgccgcca aggccuacgc cgagcagcuc     1140

aaggagaacg gcgucaucaa cuacuccguc cucgaccuca ccgccgagga gcucgaggcc     1200

aucaagcacc agcucaaccc caaggacaac gacgucgagc ucugaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10394
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10394
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccuuaauaa ggaucagcug      120

uuguccucuu caaaauacac aauccaaaga aguacuggcg acagcauuga uacgcccaac      180

uaugacgucc agaagcacau aaauaaauua ugcgggaugc ugcuaaucac cgaggaugcu      240

aaccauaagu ucacaggacu cauugguaug cuguacgcaa uguccaggcu uggccgggaa      300

gacacuauca agauucugcg cgaugccggg uaucacguua aagcgaaugg aguggacgua      360

accacacauc gacaggauau caacggcaag gagaugaaau uugaaguguu gacccucgcu      420

ucucugacua cagagauaca gaucaauauu gaaaucgagu cgcguaaguc auacaaaaag      480

augcugaagg agauggguga agucgccccu gaguauagac acgacagccc agauuguggg      540

augauuaucc ucugcauagc agccuuagug auuaccaaac uggcugcagg agacaggagu      600

ggccuuacgg ccguuauccg gcgcgcuaac aauguguuga agaacgaaau gaaaagauac      660

aagggccugc uaccgaaaga uauugccaau uccuucuaug aggucuuuga gaagcauccc      720

cacuucaucg acguguuugu acacuucggg aucgcgcaau cuagcacuag gggagguucc      780

cggguugaag gcauuuuugc aggacucuuc augaacgccu acggggcugg ccaggugaug      840

cugcgcuggg guguccuugc caaaucagug aagaauauaa ugcuggggca ugcaagugug      900

caggcugaga uggaacaggu cguugaggug uacgaauaug cccaaaaguu gggaggcgag      960

gcgggcuuuu accacauccu caacaauccu aaagccagcc uguuaucucu gacccaguuc     1020

ccacauuuuu ccucaguagu gcucgggaac gcagcuggac uugguauuau gggcgaguau     1080

cgagggacac ccagaaacca ggaccuguac gaugccgcua aggccuaugc agaacaguug     1140

aaagagaaug gagucaucaa cuacagcgug cuagaccuga cugccgagga acucgaagcu     1200

auaaagcacc aacugaaucc uaaagauaac gacguugagc uuugaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10395
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10395
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaag cugaacgaca cccugaacaa ggaccagcug      120

cugagcagca gcaaguacac cauccagaga agcaccggcg acagcaucga cacccccaac      180

uacgacgugc agaagcacau caacaagcug ugcggcaugc ugcugaucac cgaggacgcc      240

aaccacaagu ucaccggccu gaucggcaug cuguacgcca ugagcagacu gggcagagag      300

gacaccauca agauccugag agacgccggc uaccacguga aggccaacgg cguggacgug      360

accacccaca gacaggacau caacggcaag gagaugaagu ucgaggugcu gacccuggcc      420

agccugacca ccgagaucca gaucaacauc gagaucgaga gcagaaagag cuacaagaag      480

augcugaagg agaugggcga gguggccccc gaguacagac acgacagccc cgacugcggc      540

augaucaucc ugugcaucgc cgcccuggug aucaccaagc uggccgccgg cgacagaagc      600

ggccugaccg ccgugaucag aagagccaac aacgugcuga agaacgagau gaagagauac      660

aagggccugc ugcccaagga caucgccaac agcuucuacg agguguucga gaagcacccc      720

cacuucaucg acguguucgu gcacuucggc aucgcccaga gcagcaccag aggcggcagc      780

agaguggagg gcaucuucgc cggccuguuc augaacgccu acggcgccgg ccaggugaug      840

cugagauggg gcgugcuggc caagagcgug aagaacauca ugcugggcca cgccagcgug      900

caggccgaga uggagcaggu gguggaggug uacgaguacg cccagaagcu gggcggcgag      960

gccggcuucu accacauccu gaacaacccc aaggccagcc ugcugagccu gacccaguuc     1020

ccccacuuca gcagcguggu gcugggcaac gccgccggcc ugggcaucau gggcgaguac     1080

agaggcaccc ccagaaacca ggaccuguac gacgccgcca aggccuacgc cgagcagcug     1140

aaggagaacg gcgugaucaa cuacagcgug cuggaccuga ccgccgagga gcuggaggcc     1200

aucaagcacc agcugaaccc caaggacaac gacguggagc ugugaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10396
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10396
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcccugag caaggugaaa cucaacgaca cccugaauaa ggaucagcuu      120

cuguccucua gcaaauacac aauccaaaga uccacgggcg acucuauuga uacccccaac      180

uaugacgucc agaagcacau caauaaacuc ugcgggaugc ugcuuauuac agaggaugcu      240

aaccauaagu ucaccggacu gaucggcaug cucuacgcca ugagccggcu ggggcgcgaa      300

gacacaauua agauccugag agaugcggga uaucacguua aagcuaaugg cguggacgug      360

accacacauc ggcaggauau caacgggaag gagaugaaau uugaaguccu cacccuggcc      420

ucccuuacga ccgagauuca gaucaauauu gaaaucgagu cucgcaagag cuacaaaaag      480

augcugaagg agaugggaga aguggccccu gaguauagac acgacucccc ggauuguggc      540

augauuaucc ucugcauugc ugcccugguu aucacaaaac uugcugccgg cgaccggagc      600

gggcugaccg cggugauccg cagagccaac aauguccuca agaacgaaau gaaacgguac      660

aagggacugc ugcccaaaga uauugcuaau ucuuucuaug agguguuuga gaagcauccu      720

cacuucaucg acguuuuugu gcacuucggc auugcccaau ccagcacacg cgggggaucu      780

agagucgaag gcaucuuugc uggacucuuc augaacgccu acggggcggg ccaggugaug      840

cugcgguggg gcgugcuugc caaauccguc aagaauauua ugcuggggca ugcuagcguu      900

caggccgaga uggaacaggu gguggagguc uacgaauaug cucaaaagcu cggaggcgag      960

gccggguuuu accacauccu gaacaauccc aaagccucuc uucugucccu cacccaguuc     1020

ccucauuuua gcuccguggu ucugggaaac gcugcgggcc uggggaucau gggagaguau     1080

cgcggcacgc ccagaaacca ggaccucuac gaugccgcua aggccuaugc cgaacagcug     1140

aaagagaaug gcgugauuaa cuacucuguc cuugaccuga cagcugagga acucgaagcc     1200

aucaagcacc aacugaaucc uaaagauaac gacguggagc uuugaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10397
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10397
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacuaag caaagucaaa uuaaacgaca cauuaaacaa agaccaacuc      120

uuaucaucau caaaauacac aauacaaaga agcaccggag acaguaucga cacaccaaac      180

uaugacgucc aaaaacauau aaauaaauua ugcggcaugc ucuuaaucac agaagacgcc      240

aaccauaaau uuacaggauu aauaggaaug uuauaugcaa ugucacgacu agguagagaa      300

gacacaauaa aaauacuaag agacgcaggc uaucacguaa aagcaaaugg aguagacgua      360

accacacaca gacaagacau aaauggaaaa gaaaugaaau uugaaguauu aacacuagca      420

ucacuaacaa cagaaauaca aaucaacaua gaaauagaau caagaaaaag cuacaaaaaa      480

auguuaaaag aaaugggaga agucgcacca gaauauagac augauucacc agacugcgga      540

augauaauac uaugcauagc agcccuagua auuacaaaac uagcagcagg agacagaagc      600

ggauuaacag caguaauaag aagagcaaac aacguacuaa aaaacgaaau gaaaagauau      660

aaaggauuau uaccaaaaga cauagcaaac ucauucuaug aaguauucga aaaacacccc      720

cacuuuauag acgucuucgu acacuucgga auagcccaau cauccacaag aggaggauca      780

agagucgaag gaauauucgc aggauuauuc augaacgcau auggcgcagg acaaguaaug      840

cuaagauggg gaguacuagc aaaauccguc aaaaacauaa ugcuaggaca cgcaucaguu      900

caagcagaaa uggaacaagu aguagaagua uacgaauacg cccaaaaacu aggaggagaa      960

gcaggauucu accacauacu aaauaaucca aaagcaucac uacuaagccu aacccaauuu     1020

ccccacuucu caaguguagu auuaggaaau gcagcuggac uaggaauaau gggagaauac     1080

agaggaacac caagaaacca agacuuauac gacgcagcaa aagcauacgc agagcaacuu     1140

aaagaaaacg gaguaauaaa cuauagcgua cuagacuuaa cagcagaaga acuggaagca     1200

auaaaacauc aauuaaaccc gaaagacaau gacguagaau uauaaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10398
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10398
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggcacucuc gaaaguaaaa cucaacgaca cccucaacaa agaccaacuc      120

cuuuccagcu ccaaauacac cauccaacga uccaccggag acuccaucga cacgcccaac      180

uacgacgucc agaaacacau caacaagcuc ugcggaaugc uacuaaucac cgaggacgcc      240

aaccacaaau ucacaggacu uauagggaug cucuacgcca ugucccgccu cggacgcgaa      300

gacacaauaa aaauccuacg agacgccggc uaccacguaa aggcaaacgg cgucgacguc      360

accacacaca gacaagacau caacggaaag gaaaugaaau ucgaaguccu cacccucgcc      420

agccuaacca ccgagaucca aaucaacauc gaaaucgaau cacgcaaauc cuacaagaaa      480

augcucaaag aaaugggaga agucgccccc gaauaccguc acgacucgcc cgacugcggc      540

augauaaucc uaugcaucgc cgcacucguc auaaccaaac ucgccgccgg ugaccgauca      600

ggacugacag cagucauccg ccgagcaaac aacgugcuca aaaacgaaau gaaacgcuac      660

aaaggccuac uccccaaaga caucgccaac uccuucuacg aagucuucga aaaacaccca      720

cacuucaucg acgucuucgu ccacuucggc aucgcacaau caucaaccag aggcggcagc      780

cgcguugaag gcaucuucgc aggacucuuu augaacgccu acggcgccgg ccaagucaug      840

cuccgcuggg gcguccuggc aaaaagcguc aaaaacauca ugcuaggcca cgcuagcguc      900

caagccgaaa uggaacaagu cgucgaaguu uacgaguacg cacaaaaacu cggcggcgaa      960

gcaggcuucu accacauccu aaacaacccc aaagccuccc ugcuaucacu cacccaauuc     1020

ccccacuucu ccagcgucgu ccucggcaac gccgcaggac uaggcaucau gggagaauac     1080

cgcgggacac cgcgcaacca agaccucuac gacgccgcca aagccuacgc cgaacaacuc     1140

aaagaaaacg gcgucauaaa cuacucaguc cucgaccuca ccgccgaaga acucgaagcc     1200

aucaaacacc aacucaaccc aaaagacaac gacgucgaau uauaaggacu aguggaagca     1260

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu     1320

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa     1380

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1500

uuuucagagc caccagaauu                                                 1520


<210>  10399
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10399
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cucuuagcaa agucaaguug      120

aaugauacac ucaacaaaga ucaacuucug ucauccagca aauacaccau ccaacggagc      180

acaggagaua guauugauac uccuaauuau gaugugcaga aacacaucaa uaaguuaugu      240

ggcauguuau uaaucacaga agaugcuaau cauaaauuca cuggguuaau agguauguua      300

uaugcgaugu cuagguuagg aagagaagac accauaaaaa uacucagaga ugcgggauau      360

cauguaaaag caaauggagu agauguaaca acacaucguc aagacauuaa uggaaaagaa      420

augaaauuug aaguguuaac auuggcaagc uuaacaacug aaauucaaau caacauugag      480

auagaaucua gaaaauccua caaaaaaaug cuaaaagaaa ugggagaggu agcuccagaa      540

uacaggcaug acucuccuga uugugggaug auaauauuau guauagcagc auuaguaaua      600

acuaaauuag cagcagggga cagaucuggu cuuacagccg ugauuaggag agcuaauaau      660

guccuaaaaa augaaaugaa acguuacaaa ggcuuacuac ccaaggacau agccaacagc      720

uucuaugaag uguuugaaaa acauccccac uuuauagaug uuuuuguuca uuuugguaua      780

gcacaaucuu cuaccagagg uggcaguaga guugaaggga uuuuugcagg auuguuuaug      840

aaugccuaug gugcagggca agugauguua cgguggggag ucuuagcaaa aucaguuaaa      900

aauauuaugu uaggacaugc uagugugcaa gcagaaaugg aacaaguugu ugagguuuau      960

gaauaugccc aaaaauuggg uggugaagca ggauucuacc auauauugaa caacccaaaa     1020

gcaucauuau uaucuuugac ucaauuuccu cacuucucca guguaguauu aggcaaugcu     1080

gcuggccuag gcauaauggg agaguacaga gguacaccga ggaaucaaga ucuauaugau     1140

gcagcaaagg cauaugcuga acaacucaaa gaaaauggug ugauuaacua caguguacua     1200

gacuugacag cagaagaacu agaggcuauc aaacaucagc uuaauccaaa agauaaugau     1260

guagagcuuu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10400
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10400
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcuc      120

aacgacaccc ugaacaagga ccagcugcuc uccagcucca aguacaccau ccagcgcagc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcugugc      240

gggaugcugc ucaucaccga ggacgccaac cacaaguuca ccggccugau cgggaugcug      300

uacgcgauga gccggcucgg ccgcgaggac acgaucaaga uccugcggga cgccggguac      360

cacgugaagg ccaacggcgu ggacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccucgccucc cugacgaccg agauccagau caacaucgag      480

aucgagagcc ggaaguccua caagaagaug cugaaggaga ugggggaggu ggccccggag      540

uaccgccacg acagccccga cugcggcaug aucauccucu gcaucgcggc ccuggucauc      600

accaagcugg ccgccgggga ccgguccggc cucaccgcgg ugauccgccg ggccaacaac      660

gugcugaaga acgagaugaa gcgcuacaag gggcugcucc ccaaggacau cgccaacagc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagucca gcacgcgggg cgggucccgc gucgagggca ucuucgccgg gcuguucaug      840

aacgcguacg gcgccggcca ggugaugcug cgguggggcg ugcucgccaa gagcgucaag      900

aacaucaugc uggggcacgc cuccgugcag gccgagaugg agcaggucgu ggagguguac      960

gaguacgcgc agaagcucgg gggcgaggcc ggguucuacc acauccugaa caacccgaag     1020

gccagccugc ugucccucac ccaguucccc cacuucagca gcgugguccu gggcaacgcc     1080

gccggccugg ggaucauggg cgaguaccgc gggacgcccc ggaaccagga ccucuacgac     1140

gcggccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cuccgugcug     1200

gaccucaccg ccgaggagcu ggaggcgauc aagcaccagc ugaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10401
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10401
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccucuccaa ggucaagcuc      120

aacgacaccc ucaacaagga ccagcuccuc uccuccucca aguacaccau ccagcgcucc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcucugc      240

ggcaugcucc ucaucaccga ggacgccaac cacaaguuca ccggccucau cggcaugcuc      300

uacgccaugu cccgccucgg ccgcgaggac accaucaaga uccuccgcga cgccggcuac      360

cacgucaagg ccaacggcgu cgacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg agguccucac ccucgccucc cucaccaccg agauccagau caacaucgag      480

aucgaguccc gcaaguccua caagaagaug cucaaggaga ugggcgaggu cgcccccgag      540

uaccgccacg acucccccga cugcggcaug aucauccucu gcaucgccgc ccucgucauc      600

accaagcucg ccgccggcga ccgcuccggc cucaccgccg ucauccgccg cgccaacaac      660

guccucaaga acgagaugaa gcgcuacaag ggccuccucc ccaaggacau cgccaacucc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg ucuucgucca cuucggcauc      780

gcccaguccu ccacccgcgg cggcucccgc gucgagggca ucuucgccgg ccucuucaug      840

aacgccuacg gcgccggcca ggucaugcuc cgcuggggcg uccucgccaa guccgucaag      900

aacaucaugc ucggccacgc cuccguccag gccgagaugg agcaggucgu cgaggucuac      960

gaguacgccc agaagcucgg cggcgaggcc ggcuucuacc acauccucaa caaccccaag     1020

gccucccucc ucucccucac ccaguucccc cacuucuccu ccgucguccu cggcaacgcc     1080

gccggccucg gcaucauggg cgaguaccgc ggcacccccc gcaaccagga ccucuacgac     1140

gccgccaagg ccuacgccga gcagcucaag gagaacggcg ucaucaacua cuccguccuc     1200

gaccucaccg ccgaggagcu cgaggccauc aagcaccagc ucaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10402
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10402
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc uuaauaagga ucagcuguug uccucuucaa aauacacaau ccaaagaagu      180

acuggcgaca gcauugauac gcccaacuau gacguccaga agcacauaaa uaaauuaugc      240

gggaugcugc uaaucaccga ggaugcuaac cauaaguuca caggacucau ugguaugcug      300

uacgcaaugu ccaggcuugg ccgggaagac acuaucaaga uucugcgcga ugccggguau      360

cacguuaaag cgaauggagu ggacguaacc acacaucgac aggauaucaa cggcaaggag      420

augaaauuug aaguguugac ccucgcuucu cugacuacag agauacagau caauauugaa      480

aucgagucgc guaagucaua caaaaagaug cugaaggaga ugggugaagu cgccccugag      540

uauagacacg acagcccaga uugugggaug auuauccucu gcauagcagc cuuagugauu      600

accaaacugg cugcaggaga caggaguggc cuuacggccg uuauccggcg cgcuaacaau      660

guguugaaga acgaaaugaa aagauacaag ggccugcuac cgaaagauau ugccaauucc      720

uucuaugagg ucuuugagaa gcauccccac uucaucgacg uguuuguaca cuucgggauc      780

gcgcaaucua gcacuagggg agguucccgg guugaaggca uuuuugcagg acucuucaug      840

aacgccuacg gggcuggcca ggugaugcug cgcuggggug uccuugccaa aucagugaag      900

aauauaaugc uggggcaugc aagugugcag gcugagaugg aacaggucgu ugagguguac      960

gaauaugccc aaaaguuggg aggcgaggcg ggcuuuuacc acauccucaa caauccuaaa     1020

gccagccugu uaucucugac ccaguuccca cauuuuuccu caguagugcu cgggaacgca     1080

gcuggacuug guauuauggg cgaguaucga gggacaccca gaaaccagga ccuguacgau     1140

gccgcuaagg ccuaugcaga acaguugaaa gagaauggag ucaucaacua cagcgugcua     1200

gaccugacug ccgaggaacu cgaagcuaua aagcaccaac ugaauccuaa agauaacgac     1260

guugagcuuu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10403
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10403
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcug      120

aacgacaccc ugaacaagga ccagcugcug agcagcagca aguacaccau ccagagaagc      180

accggcgaca gcaucgacac ccccaacuac gacgugcaga agcacaucaa caagcugugc      240

ggcaugcugc ugaucaccga ggacgccaac cacaaguuca ccggccugau cggcaugcug      300

uacgccauga gcagacuggg cagagaggac accaucaaga uccugagaga cgccggcuac      360

cacgugaagg ccaacggcgu ggacgugacc acccacagac aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccuggccagc cugaccaccg agauccagau caacaucgag      480

aucgagagca gaaagagcua caagaagaug cugaaggaga ugggcgaggu ggcccccgag      540

uacagacacg acagccccga cugcggcaug aucauccugu gcaucgccgc ccuggugauc      600

accaagcugg ccgccggcga cagaagcggc cugaccgccg ugaucagaag agccaacaac      660

gugcugaaga acgagaugaa gagauacaag ggccugcugc ccaaggacau cgccaacagc      720

uucuacgagg uguucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagagca gcaccagagg cggcagcaga guggagggca ucuucgccgg ccuguucaug      840

aacgccuacg gcgccggcca ggugaugcug agauggggcg ugcuggccaa gagcgugaag      900

aacaucaugc ugggccacgc cagcgugcag gccgagaugg agcagguggu ggagguguac      960

gaguacgccc agaagcuggg cggcgaggcc ggcuucuacc acauccugaa caaccccaag     1020

gccagccugc ugagccugac ccaguucccc cacuucagca gcguggugcu gggcaacgcc     1080

gccggccugg gcaucauggg cgaguacaga ggcaccccca gaaaccagga ccuguacgac     1140

gccgccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cagcgugcug     1200

gaccugaccg ccgaggagcu ggaggccauc aagcaccagc ugaaccccaa ggacaacgac     1260

guggagcugu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10404
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10404
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc ugaauaagga ucagcuucug uccucuagca aauacacaau ccaaagaucc      180

acgggcgacu cuauugauac ccccaacuau gacguccaga agcacaucaa uaaacucugc      240

gggaugcugc uuauuacaga ggaugcuaac cauaaguuca ccggacugau cggcaugcuc      300

uacgccauga gccggcuggg gcgcgaagac acaauuaaga uccugagaga ugcgggauau      360

cacguuaaag cuaauggcgu ggacgugacc acacaucggc aggauaucaa cgggaaggag      420

augaaauuug aaguccucac ccuggccucc cuuacgaccg agauucagau caauauugaa      480

aucgagucuc gcaagagcua caaaaagaug cugaaggaga ugggagaagu ggccccugag      540

uauagacacg acuccccgga uuguggcaug auuauccucu gcauugcugc ccugguuauc      600

acaaaacuug cugccggcga ccggagcggg cugaccgcgg ugauccgcag agccaacaau      660

guccucaaga acgaaaugaa acgguacaag ggacugcugc ccaaagauau ugcuaauucu      720

uucuaugagg uguuugagaa gcauccucac uucaucgacg uuuuugugca cuucggcauu      780

gcccaaucca gcacacgcgg gggaucuaga gucgaaggca ucuuugcugg acucuucaug      840

aacgccuacg gggcgggcca ggugaugcug cgguggggcg ugcuugccaa auccgucaag      900

aauauuaugc uggggcaugc uagcguucag gccgagaugg aacagguggu ggaggucuac      960

gaauaugcuc aaaagcucgg aggcgaggcc ggguuuuacc acauccugaa caaucccaaa     1020

gccucucuuc ugucccucac ccaguucccu cauuuuagcu ccgugguucu gggaaacgcu     1080

gcgggccugg ggaucauggg agaguaucgc ggcacgccca gaaaccagga ccucuacgau     1140

gccgcuaagg ccuaugccga acagcugaaa gagaauggcg ugauuaacua cucuguccuu     1200

gaccugacag cugaggaacu cgaagccauc aagcaccaac ugaauccuaa agauaacgac     1260

guggagcuuu gaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10405
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10405
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacuaagcaa agucaaauua      120

aacgacacau uaaacaaaga ccaacucuua ucaucaucaa aauacacaau acaaagaagc      180

accggagaca guaucgacac accaaacuau gacguccaaa aacauauaaa uaaauuaugc      240

ggcaugcucu uaaucacaga agacgccaac cauaaauuua caggauuaau aggaauguua      300

uaugcaaugu cacgacuagg uagagaagac acaauaaaaa uacuaagaga cgcaggcuau      360

cacguaaaag caaauggagu agacguaacc acacacagac aagacauaaa uggaaaagaa      420

augaaauuug aaguauuaac acuagcauca cuaacaacag aaauacaaau caacauagaa      480

auagaaucaa gaaaaagcua caaaaaaaug uuaaaagaaa ugggagaagu cgcaccagaa      540

uauagacaug auucaccaga cugcggaaug auaauacuau gcauagcagc ccuaguaauu      600

acaaaacuag cagcaggaga cagaagcgga uuaacagcag uaauaagaag agcaaacaac      660

guacuaaaaa acgaaaugaa aagauauaaa ggauuauuac caaaagacau agcaaacuca      720

uucuaugaag uauucgaaaa acacccccac uuuauagacg ucuucguaca cuucggaaua      780

gcccaaucau ccacaagagg aggaucaaga gucgaaggaa uauucgcagg auuauucaug      840

aacgcauaug gcgcaggaca aguaaugcua agauggggag uacuagcaaa auccgucaaa      900

aacauaaugc uaggacacgc aucaguucaa gcagaaaugg aacaaguagu agaaguauac      960

gaauacgccc aaaaacuagg aggagaagca ggauucuacc acauacuaaa uaauccaaaa     1020

gcaucacuac uaagccuaac ccaauuuccc cacuucucaa guguaguauu aggaaaugca     1080

gcuggacuag gaauaauggg agaauacaga ggaacaccaa gaaaccaaga cuuauacgac     1140

gcagcaaaag cauacgcaga gcaacuuaaa gaaaacggag uaauaaacua uagcguacua     1200

gacuuaacag cagaagaacu ggaagcaaua aaacaucaau uaaacccgaa agacaaugac     1260

guagaauuau aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10406
<211>  1535
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10406
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacucucgaa aguaaaacuc      120

aacgacaccc ucaacaaaga ccaacuccuu uccagcucca aauacaccau ccaacgaucc      180

accggagacu ccaucgacac gcccaacuac gacguccaga aacacaucaa caagcucugc      240

ggaaugcuac uaaucaccga ggacgccaac cacaaauuca caggacuuau agggaugcuc      300

uacgccaugu cccgccucgg acgcgaagac acaauaaaaa uccuacgaga cgccggcuac      360

cacguaaagg caaacggcgu cgacgucacc acacacagac aagacaucaa cggaaaggaa      420

augaaauucg aaguccucac ccucgccagc cuaaccaccg agauccaaau caacaucgaa      480

aucgaaucac gcaaauccua caagaaaaug cucaaagaaa ugggagaagu cgcccccgaa      540

uaccgucacg acucgcccga cugcggcaug auaauccuau gcaucgccgc acucgucaua      600

accaaacucg ccgccgguga ccgaucagga cugacagcag ucauccgccg agcaaacaac      660

gugcucaaaa acgaaaugaa acgcuacaaa ggccuacucc ccaaagacau cgccaacucc      720

uucuacgaag ucuucgaaaa acacccacac uucaucgacg ucuucgucca cuucggcauc      780

gcacaaucau caaccagagg cggcagccgc guugaaggca ucuucgcagg acucuuuaug      840

aacgccuacg gcgccggcca agucaugcuc cgcuggggcg uccuggcaaa aagcgucaaa      900

aacaucaugc uaggccacgc uagcguccaa gccgaaaugg aacaagucgu cgaaguuuac      960

gaguacgcac aaaaacucgg cggcgaagca ggcuucuacc acauccuaaa caaccccaaa     1020

gccucccugc uaucacucac ccaauucccc cacuucucca gcgucguccu cggcaacgcc     1080

gcaggacuag gcaucauggg agaauaccgc gggacaccgc gcaaccaaga ccucuacgac     1140

gccgccaaag ccuacgccga acaacucaaa gaaaacggcg ucauaaacua cucaguccuc     1200

gaccucaccg ccgaagaacu cgaagccauc aaacaccaac ucaacccaaa agacaacgac     1260

gucgaauuau aaggacuagu aauaaggaaa cuguaugaau gucugugggc aggaagugaa     1320

gagauccuuc uguaaagguu uuuggaauua ugucugcuga auaauaaacu uuuuugaaau     1380

aauaaaucug guagaaaaau gagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1500

cccccccaaa ggcucuuuuc agagccacca gaauu                                1535


<210>  10407
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10407
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cucuuagcaa agucaaguug      120

aaugauacac ucaacaaaga ucaacuucug ucauccagca aauacaccau ccaacggagc      180

acaggagaua guauugauac uccuaauuau gaugugcaga aacacaucaa uaaguuaugu      240

ggcauguuau uaaucacaga agaugcuaau cauaaauuca cuggguuaau agguauguua      300

uaugcgaugu cuagguuagg aagagaagac accauaaaaa uacucagaga ugcgggauau      360

cauguaaaag caaauggagu agauguaaca acacaucguc aagacauuaa uggaaaagaa      420

augaaauuug aaguguuaac auuggcaagc uuaacaacug aaauucaaau caacauugag      480

auagaaucua gaaaauccua caaaaaaaug cuaaaagaaa ugggagaggu agcuccagaa      540

uacaggcaug acucuccuga uugugggaug auaauauuau guauagcagc auuaguaaua      600

acuaaauuag cagcagggga cagaucuggu cuuacagccg ugauuaggag agcuaauaau      660

guccuaaaaa augaaaugaa acguuacaaa ggcuuacuac ccaaggacau agccaacagc      720

uucuaugaag uguuugaaaa acauccccac uuuauagaug uuuuuguuca uuuugguaua      780

gcacaaucuu cuaccagagg uggcaguaga guugaaggga uuuuugcagg auuguuuaug      840

aaugccuaug gugcagggca agugauguua cgguggggag ucuuagcaaa aucaguuaaa      900

aauauuaugu uaggacaugc uagugugcaa gcagaaaugg aacaaguugu ugagguuuau      960

gaauaugccc aaaaauuggg uggugaagca ggauucuacc auauauugaa caacccaaaa     1020

gcaucauuau uaucuuugac ucaauuuccu cacuucucca guguaguauu aggcaaugcu     1080

gcuggccuag gcauaauggg agaguacaga gguacaccga ggaaucaaga ucuauaugau     1140

gcagcaaagg cauaugcuga acaacucaaa gaaaauggug ugauuaacua caguguacua     1200

gacuugacag cagaagaacu agaggcuauc aaacaucagc uuaauccaaa agauaaugau     1260

guagagcuuu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10408
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10408
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcuc      120

aacgacaccc ugaacaagga ccagcugcuc uccagcucca aguacaccau ccagcgcagc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcugugc      240

gggaugcugc ucaucaccga ggacgccaac cacaaguuca ccggccugau cgggaugcug      300

uacgcgauga gccggcucgg ccgcgaggac acgaucaaga uccugcggga cgccggguac      360

cacgugaagg ccaacggcgu ggacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccucgccucc cugacgaccg agauccagau caacaucgag      480

aucgagagcc ggaaguccua caagaagaug cugaaggaga ugggggaggu ggccccggag      540

uaccgccacg acagccccga cugcggcaug aucauccucu gcaucgcggc ccuggucauc      600

accaagcugg ccgccgggga ccgguccggc cucaccgcgg ugauccgccg ggccaacaac      660

gugcugaaga acgagaugaa gcgcuacaag gggcugcucc ccaaggacau cgccaacagc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagucca gcacgcgggg cgggucccgc gucgagggca ucuucgccgg gcuguucaug      840

aacgcguacg gcgccggcca ggugaugcug cgguggggcg ugcucgccaa gagcgucaag      900

aacaucaugc uggggcacgc cuccgugcag gccgagaugg agcaggucgu ggagguguac      960

gaguacgcgc agaagcucgg gggcgaggcc ggguucuacc acauccugaa caacccgaag     1020

gccagccugc ugucccucac ccaguucccc cacuucagca gcgugguccu gggcaacgcc     1080

gccggccugg ggaucauggg cgaguaccgc gggacgcccc ggaaccagga ccucuacgac     1140

gcggccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cuccgugcug     1200

gaccucaccg ccgaggagcu ggaggcgauc aagcaccagc ugaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10409
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10409
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccucuccaa ggucaagcuc      120

aacgacaccc ucaacaagga ccagcuccuc uccuccucca aguacaccau ccagcgcucc      180

accggcgacu ccaucgacac ccccaacuac gacguccaga agcacaucaa caagcucugc      240

ggcaugcucc ucaucaccga ggacgccaac cacaaguuca ccggccucau cggcaugcuc      300

uacgccaugu cccgccucgg ccgcgaggac accaucaaga uccuccgcga cgccggcuac      360

cacgucaagg ccaacggcgu cgacgucacc acccaccgcc aggacaucaa cggcaaggag      420

augaaguucg agguccucac ccucgccucc cucaccaccg agauccagau caacaucgag      480

aucgaguccc gcaaguccua caagaagaug cucaaggaga ugggcgaggu cgcccccgag      540

uaccgccacg acucccccga cugcggcaug aucauccucu gcaucgccgc ccucgucauc      600

accaagcucg ccgccggcga ccgcuccggc cucaccgccg ucauccgccg cgccaacaac      660

guccucaaga acgagaugaa gcgcuacaag ggccuccucc ccaaggacau cgccaacucc      720

uucuacgagg ucuucgagaa gcacccccac uucaucgacg ucuucgucca cuucggcauc      780

gcccaguccu ccacccgcgg cggcucccgc gucgagggca ucuucgccgg ccucuucaug      840

aacgccuacg gcgccggcca ggucaugcuc cgcuggggcg uccucgccaa guccgucaag      900

aacaucaugc ucggccacgc cuccguccag gccgagaugg agcaggucgu cgaggucuac      960

gaguacgccc agaagcucgg cggcgaggcc ggcuucuacc acauccucaa caaccccaag     1020

gccucccucc ucucccucac ccaguucccc cacuucuccu ccgucguccu cggcaacgcc     1080

gccggccucg gcaucauggg cgaguaccgc ggcacccccc gcaaccagga ccucuacgac     1140

gccgccaagg ccuacgccga gcagcucaag gagaacggcg ucaucaacua cuccguccuc     1200

gaccucaccg ccgaggagcu cgaggccauc aagcaccagc ucaaccccaa ggacaacgac     1260

gucgagcucu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10410
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10410
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc uuaauaagga ucagcuguug uccucuucaa aauacacaau ccaaagaagu      180

acuggcgaca gcauugauac gcccaacuau gacguccaga agcacauaaa uaaauuaugc      240

gggaugcugc uaaucaccga ggaugcuaac cauaaguuca caggacucau ugguaugcug      300

uacgcaaugu ccaggcuugg ccgggaagac acuaucaaga uucugcgcga ugccggguau      360

cacguuaaag cgaauggagu ggacguaacc acacaucgac aggauaucaa cggcaaggag      420

augaaauuug aaguguugac ccucgcuucu cugacuacag agauacagau caauauugaa      480

aucgagucgc guaagucaua caaaaagaug cugaaggaga ugggugaagu cgccccugag      540

uauagacacg acagcccaga uugugggaug auuauccucu gcauagcagc cuuagugauu      600

accaaacugg cugcaggaga caggaguggc cuuacggccg uuauccggcg cgcuaacaau      660

guguugaaga acgaaaugaa aagauacaag ggccugcuac cgaaagauau ugccaauucc      720

uucuaugagg ucuuugagaa gcauccccac uucaucgacg uguuuguaca cuucgggauc      780

gcgcaaucua gcacuagggg agguucccgg guugaaggca uuuuugcagg acucuucaug      840

aacgccuacg gggcuggcca ggugaugcug cgcuggggug uccuugccaa aucagugaag      900

aauauaaugc uggggcaugc aagugugcag gcugagaugg aacaggucgu ugagguguac      960

gaauaugccc aaaaguuggg aggcgaggcg ggcuuuuacc acauccucaa caauccuaaa     1020

gccagccugu uaucucugac ccaguuccca cauuuuuccu caguagugcu cgggaacgca     1080

gcuggacuug guauuauggg cgaguaucga gggacaccca gaaaccagga ccuguacgau     1140

gccgcuaagg ccuaugcaga acaguugaaa gagaauggag ucaucaacua cagcgugcua     1200

gaccugacug ccgaggaacu cgaagcuaua aagcaccaac ugaauccuaa agauaacgac     1260

guugagcuuu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10411
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10411
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaagcug      120

aacgacaccc ugaacaagga ccagcugcug agcagcagca aguacaccau ccagagaagc      180

accggcgaca gcaucgacac ccccaacuac gacgugcaga agcacaucaa caagcugugc      240

ggcaugcugc ugaucaccga ggacgccaac cacaaguuca ccggccugau cggcaugcug      300

uacgccauga gcagacuggg cagagaggac accaucaaga uccugagaga cgccggcuac      360

cacgugaagg ccaacggcgu ggacgugacc acccacagac aggacaucaa cggcaaggag      420

augaaguucg aggugcugac ccuggccagc cugaccaccg agauccagau caacaucgag      480

aucgagagca gaaagagcua caagaagaug cugaaggaga ugggcgaggu ggcccccgag      540

uacagacacg acagccccga cugcggcaug aucauccugu gcaucgccgc ccuggugauc      600

accaagcugg ccgccggcga cagaagcggc cugaccgccg ugaucagaag agccaacaac      660

gugcugaaga acgagaugaa gagauacaag ggccugcugc ccaaggacau cgccaacagc      720

uucuacgagg uguucgagaa gcacccccac uucaucgacg uguucgugca cuucggcauc      780

gcccagagca gcaccagagg cggcagcaga guggagggca ucuucgccgg ccuguucaug      840

aacgccuacg gcgccggcca ggugaugcug agauggggcg ugcuggccaa gagcgugaag      900

aacaucaugc ugggccacgc cagcgugcag gccgagaugg agcagguggu ggagguguac      960

gaguacgccc agaagcuggg cggcgaggcc ggcuucuacc acauccugaa caaccccaag     1020

gccagccugc ugagccugac ccaguucccc cacuucagca gcguggugcu gggcaacgcc     1080

gccggccugg gcaucauggg cgaguacaga ggcaccccca gaaaccagga ccuguacgac     1140

gccgccaagg ccuacgccga gcagcugaag gagaacggcg ugaucaacua cagcgugcug     1200

gaccugaccg ccgaggagcu ggaggccauc aagcaccagc ugaaccccaa ggacaacgac     1260

guggagcugu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10412
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10412
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cccugagcaa ggugaaacuc      120

aacgacaccc ugaauaagga ucagcuucug uccucuagca aauacacaau ccaaagaucc      180

acgggcgacu cuauugauac ccccaacuau gacguccaga agcacaucaa uaaacucugc      240

gggaugcugc uuauuacaga ggaugcuaac cauaaguuca ccggacugau cggcaugcuc      300

uacgccauga gccggcuggg gcgcgaagac acaauuaaga uccugagaga ugcgggauau      360

cacguuaaag cuaauggcgu ggacgugacc acacaucggc aggauaucaa cgggaaggag      420

augaaauuug aaguccucac ccuggccucc cuuacgaccg agauucagau caauauugaa      480

aucgagucuc gcaagagcua caaaaagaug cugaaggaga ugggagaagu ggccccugag      540

uauagacacg acuccccgga uuguggcaug auuauccucu gcauugcugc ccugguuauc      600

acaaaacuug cugccggcga ccggagcggg cugaccgcgg ugauccgcag agccaacaau      660

guccucaaga acgaaaugaa acgguacaag ggacugcugc ccaaagauau ugcuaauucu      720

uucuaugagg uguuugagaa gcauccucac uucaucgacg uuuuugugca cuucggcauu      780

gcccaaucca gcacacgcgg gggaucuaga gucgaaggca ucuuugcugg acucuucaug      840

aacgccuacg gggcgggcca ggugaugcug cgguggggcg ugcuugccaa auccgucaag      900

aauauuaugc uggggcaugc uagcguucag gccgagaugg aacagguggu ggaggucuac      960

gaauaugcuc aaaagcucgg aggcgaggcc ggguuuuacc acauccugaa caaucccaaa     1020

gccucucuuc ugucccucac ccaguucccu cauuuuagcu ccgugguucu gggaaacgcu     1080

gcgggccugg ggaucauggg agaguaucgc ggcacgccca gaaaccagga ccucuacgau     1140

gccgcuaagg ccuaugccga acagcugaaa gagaauggcg ugauuaacua cucuguccuu     1200

gaccugacag cugaggaacu cgaagccauc aagcaccaac ugaauccuaa agauaacgac     1260

guggagcuuu gaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10413
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10413
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacuaagcaa agucaaauua      120

aacgacacau uaaacaaaga ccaacucuua ucaucaucaa aauacacaau acaaagaagc      180

accggagaca guaucgacac accaaacuau gacguccaaa aacauauaaa uaaauuaugc      240

ggcaugcucu uaaucacaga agacgccaac cauaaauuua caggauuaau aggaauguua      300

uaugcaaugu cacgacuagg uagagaagac acaauaaaaa uacuaagaga cgcaggcuau      360

cacguaaaag caaauggagu agacguaacc acacacagac aagacauaaa uggaaaagaa      420

augaaauuug aaguauuaac acuagcauca cuaacaacag aaauacaaau caacauagaa      480

auagaaucaa gaaaaagcua caaaaaaaug uuaaaagaaa ugggagaagu cgcaccagaa      540

uauagacaug auucaccaga cugcggaaug auaauacuau gcauagcagc ccuaguaauu      600

acaaaacuag cagcaggaga cagaagcgga uuaacagcag uaauaagaag agcaaacaac      660

guacuaaaaa acgaaaugaa aagauauaaa ggauuauuac caaaagacau agcaaacuca      720

uucuaugaag uauucgaaaa acacccccac uuuauagacg ucuucguaca cuucggaaua      780

gcccaaucau ccacaagagg aggaucaaga gucgaaggaa uauucgcagg auuauucaug      840

aacgcauaug gcgcaggaca aguaaugcua agauggggag uacuagcaaa auccgucaaa      900

aacauaaugc uaggacacgc aucaguucaa gcagaaaugg aacaaguagu agaaguauac      960

gaauacgccc aaaaacuagg aggagaagca ggauucuacc acauacuaaa uaauccaaaa     1020

gcaucacuac uaagccuaac ccaauuuccc cacuucucaa guguaguauu aggaaaugca     1080

gcuggacuag gaauaauggg agaauacaga ggaacaccaa gaaaccaaga cuuauacgac     1140

gcagcaaaag cauacgcaga gcaacuuaaa gaaaacggag uaauaaacua uagcguacua     1200

gacuuaacag cagaagaacu ggaagcaaua aaacaucaau uaaacccgaa agacaaugac     1260

guagaauuau aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10414
<211>  1767
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10414
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg cacucucgaa aguaaaacuc      120

aacgacaccc ucaacaaaga ccaacuccuu uccagcucca aauacaccau ccaacgaucc      180

accggagacu ccaucgacac gcccaacuac gacguccaga aacacaucaa caagcucugc      240

ggaaugcuac uaaucaccga ggacgccaac cacaaauuca caggacuuau agggaugcuc      300

uacgccaugu cccgccucgg acgcgaagac acaauaaaaa uccuacgaga cgccggcuac      360

cacguaaagg caaacggcgu cgacgucacc acacacagac aagacaucaa cggaaaggaa      420

augaaauucg aaguccucac ccucgccagc cuaaccaccg agauccaaau caacaucgaa      480

aucgaaucac gcaaauccua caagaaaaug cucaaagaaa ugggagaagu cgcccccgaa      540

uaccgucacg acucgcccga cugcggcaug auaauccuau gcaucgccgc acucgucaua      600

accaaacucg ccgccgguga ccgaucagga cugacagcag ucauccgccg agcaaacaac      660

gugcucaaaa acgaaaugaa acgcuacaaa ggccuacucc ccaaagacau cgccaacucc      720

uucuacgaag ucuucgaaaa acacccacac uucaucgacg ucuucgucca cuucggcauc      780

gcacaaucau caaccagagg cggcagccgc guugaaggca ucuucgcagg acucuuuaug      840

aacgccuacg gcgccggcca agucaugcuc cgcuggggcg uccuggcaaa aagcgucaaa      900

aacaucaugc uaggccacgc uagcguccaa gccgaaaugg aacaagucgu cgaaguuuac      960

gaguacgcac aaaaacucgg cggcgaagca ggcuucuacc acauccuaaa caaccccaaa     1020

gccucccugc uaucacucac ccaauucccc cacuucucca gcgucguccu cggcaacgcc     1080

gcaggacuag gcaucauggg agaauaccgc gggacaccgc gcaaccaaga ccucuacgac     1140

gccgccaaag ccuacgccga acaacucaaa gaaaacggcg ucauaaacua cucaguccuc     1200

gaccucaccg ccgaagaacu cgaagccauc aaacaccaac ucaacccaaa agacaacgac     1260

gucgaauuau aaggacuagu gaagggaaca cccaaauuua auucagccuu aagcacaauu     1320

aauuaagagu gaaacguaau uguacaagca guuggucacc caccauaggg caugaucaac     1380

accgcaaccu uuccuuuuuc ccccagugau ucugaaaaac cccucuuccc uucagcuugc     1440

uuagauguuc caaauuuagu aagcuuaagg cggccuacag aagaaaaaga aaaaaaaggc     1500

cacaaaaguu cccucucacu uucaguaaau aaaauaaaag cagcaacaga aauaaagaaa     1560

uaaaugaaau ucaaaaugaa auaaauauug uguugugcag cauuaaaaaa ucaauaaaaa     1620

uuaaaaauga gcaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1740

aaggcucuuu ucagagccac cagaauu                                         1767


<210>  10415
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10415
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcuc uuagcaaagu caaguugaau gauacacuca acaaagauca acuucuguca      180

uccagcaaau acaccaucca acggagcaca ggagauagua uugauacucc uaauuaugau      240

gugcagaaac acaucaauaa guuauguggc auguuauuaa ucacagaaga ugcuaaucau      300

aaauucacug gguuaauagg uauguuauau gcgaugucua gguuaggaag agaagacacc      360

auaaaaauac ucagagaugc gggauaucau guaaaagcaa auggaguaga uguaacaaca      420

caucgucaag acauuaaugg aaaagaaaug aaauuugaag uguuaacauu ggcaagcuua      480

acaacugaaa uucaaaucaa cauugagaua gaaucuagaa aauccuacaa aaaaaugcua      540

aaagaaaugg gagagguagc uccagaauac aggcaugacu cuccugauug ugggaugaua      600

auauuaugua uagcagcauu aguaauaacu aaauuagcag caggggacag aucuggucuu      660

acagccguga uuaggagagc uaauaauguc cuaaaaaaug aaaugaaacg uuacaaaggc      720

uuacuaccca aggacauagc caacagcuuc uaugaagugu uugaaaaaca uccccacuuu      780

auagauguuu uuguucauuu ugguauagca caaucuucua ccagaggugg caguagaguu      840

gaagggauuu uugcaggauu guuuaugaau gccuauggug cagggcaagu gauguuacgg      900

uggggagucu uagcaaaauc aguuaaaaau auuauguuag gacaugcuag ugugcaagca      960

gaaauggaac aaguuguuga gguuuaugaa uaugcccaaa aauugggugg ugaagcagga     1020

uucuaccaua uauugaacaa cccaaaagca ucauuauuau cuuugacuca auuuccucac     1080

uucuccagug uaguauuagg caaugcugcu ggccuaggca uaaugggaga guacagaggu     1140

acaccgagga aucaagaucu auaugaugca gcaaaggcau augcugaaca acucaaagaa     1200

aaugguguga uuaacuacag uguacuagac uugacagcag aagaacuaga ggcuaucaaa     1260

caucagcuua auccaaaaga uaaugaugua gagcuuugag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10416
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10416
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcucaac gacacccuga acaaggacca gcugcucucc      180

agcuccaagu acaccaucca gcgcagcacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcugugcggg augcugcuca ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg gaugcuguac gcgaugagcc ggcucggccg cgaggacacg      360

aucaagaucc ugcgggacgc cggguaccac gugaaggcca acggcgugga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg ugcugacccu cgccucccug      480

acgaccgaga uccagaucaa caucgagauc gagagccgga aguccuacaa gaagaugcug      540

aaggagaugg gggagguggc cccggaguac cgccacgaca gccccgacug cggcaugauc      600

auccucugca ucgcggcccu ggucaucacc aagcuggccg ccggggaccg guccggccuc      660

accgcgguga uccgccgggc caacaacgug cugaagaacg agaugaagcg cuacaagggg      720

cugcucccca aggacaucgc caacagcuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc caguccagca cgcggggcgg gucccgcguc      840

gagggcaucu ucgccgggcu guucaugaac gcguacggcg ccggccaggu gaugcugcgg      900

uggggcgugc ucgccaagag cgucaagaac aucaugcugg ggcacgccuc cgugcaggcc      960

gagauggagc aggucgugga gguguacgag uacgcgcaga agcucggggg cgaggccggg     1020

uucuaccaca uccugaacaa cccgaaggcc agccugcugu cccucaccca guucccccac     1080

uucagcagcg ugguccuggg caacgccgcc ggccugggga ucaugggcga guaccgcggg     1140

acgccccgga accaggaccu cuacgacgcg gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacuc cgugcuggac cucaccgccg aggagcugga ggcgaucaag     1260

caccagcuga accccaagga caacgacguc gagcucugag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10417
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10417
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ucuccaaggu caagcucaac gacacccuca acaaggacca gcuccucucc      180

uccuccaagu acaccaucca gcgcuccacc ggcgacucca ucgacacccc caacuacgac      240

guccagaagc acaucaacaa gcucugcggc augcuccuca ucaccgagga cgccaaccac      300

aaguucaccg gccucaucgg caugcucuac gccauguccc gccucggccg cgaggacacc      360

aucaagaucc uccgcgacgc cggcuaccac gucaaggcca acggcgucga cgucaccacc      420

caccgccagg acaucaacgg caaggagaug aaguucgagg uccucacccu cgccucccuc      480

accaccgaga uccagaucaa caucgagauc gagucccgca aguccuacaa gaagaugcuc      540

aaggagaugg gcgaggucgc ccccgaguac cgccacgacu cccccgacug cggcaugauc      600

auccucugca ucgccgcccu cgucaucacc aagcucgccg ccggcgaccg cuccggccuc      660

accgccguca uccgccgcgc caacaacguc cucaagaacg agaugaagcg cuacaagggc      720

cuccucccca aggacaucgc caacuccuuc uacgaggucu ucgagaagca cccccacuuc      780

aucgacgucu ucguccacuu cggcaucgcc caguccucca cccgcggcgg cucccgcguc      840

gagggcaucu ucgccggccu cuucaugaac gccuacggcg ccggccaggu caugcuccgc      900

uggggcgucc ucgccaaguc cgucaagaac aucaugcucg gccacgccuc cguccaggcc      960

gagauggagc aggucgucga ggucuacgag uacgcccaga agcucggcgg cgaggccggc     1020

uucuaccaca uccucaacaa ccccaaggcc ucccuccucu cccucaccca guucccccac     1080

uucuccuccg ucguccucgg caacgccgcc ggccucggca ucaugggcga guaccgcggc     1140

accccccgca accaggaccu cuacgacgcc gccaaggccu acgccgagca gcucaaggag     1200

aacggcguca ucaacuacuc cguccucgac cucaccgccg aggagcucga ggccaucaag     1260

caccagcuca accccaagga caacgacguc gagcucugag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10418
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10418
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuua auaaggauca gcuguugucc      180

ucuucaaaau acacaaucca aagaaguacu ggcgacagca uugauacgcc caacuaugac      240

guccagaagc acauaaauaa auuaugcggg augcugcuaa ucaccgagga ugcuaaccau      300

aaguucacag gacucauugg uaugcuguac gcaaugucca ggcuuggccg ggaagacacu      360

aucaagauuc ugcgcgaugc cggguaucac guuaaagcga auggagugga cguaaccaca      420

caucgacagg auaucaacgg caaggagaug aaauuugaag uguugacccu cgcuucucug      480

acuacagaga uacagaucaa uauugaaauc gagucgcgua agucauacaa aaagaugcug      540

aaggagaugg gugaagucgc cccugaguau agacacgaca gcccagauug ugggaugauu      600

auccucugca uagcagccuu agugauuacc aaacuggcug caggagacag gaguggccuu      660

acggccguua uccggcgcgc uaacaaugug uugaagaacg aaaugaaaag auacaagggc      720

cugcuaccga aagauauugc caauuccuuc uaugaggucu uugagaagca uccccacuuc      780

aucgacgugu uuguacacuu cgggaucgcg caaucuagca cuaggggagg uucccggguu      840

gaaggcauuu uugcaggacu cuucaugaac gccuacgggg cuggccaggu gaugcugcgc      900

uggggugucc uugccaaauc agugaagaau auaaugcugg ggcaugcaag ugugcaggcu      960

gagauggaac aggucguuga gguguacgaa uaugcccaaa aguugggagg cgaggcgggc     1020

uuuuaccaca uccucaacaa uccuaaagcc agccuguuau cucugaccca guucccacau     1080

uuuuccucag uagugcucgg gaacgcagcu ggacuuggua uuaugggcga guaucgaggg     1140

acacccagaa accaggaccu guacgaugcc gcuaaggccu augcagaaca guugaaagag     1200

aauggaguca ucaacuacag cgugcuagac cugacugccg aggaacucga agcuauaaag     1260

caccaacuga auccuaaaga uaacgacguu gagcuuugag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10419
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10419
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaagcugaac gacacccuga acaaggacca gcugcugagc      180

agcagcaagu acaccaucca gagaagcacc ggcgacagca ucgacacccc caacuacgac      240

gugcagaagc acaucaacaa gcugugcggc augcugcuga ucaccgagga cgccaaccac      300

aaguucaccg gccugaucgg caugcuguac gccaugagca gacugggcag agaggacacc      360

aucaagaucc ugagagacgc cggcuaccac gugaaggcca acggcgugga cgugaccacc      420

cacagacagg acaucaacgg caaggagaug aaguucgagg ugcugacccu ggccagccug      480

accaccgaga uccagaucaa caucgagauc gagagcagaa agagcuacaa gaagaugcug      540

aaggagaugg gcgagguggc ccccgaguac agacacgaca gccccgacug cggcaugauc      600

auccugugca ucgccgcccu ggugaucacc aagcuggccg ccggcgacag aagcggccug      660

accgccguga ucagaagagc caacaacgug cugaagaacg agaugaagag auacaagggc      720

cugcugccca aggacaucgc caacagcuuc uacgaggugu ucgagaagca cccccacuuc      780

aucgacgugu ucgugcacuu cggcaucgcc cagagcagca ccagaggcgg cagcagagug      840

gagggcaucu ucgccggccu guucaugaac gccuacggcg ccggccaggu gaugcugaga      900

uggggcgugc uggccaagag cgugaagaac aucaugcugg gccacgccag cgugcaggcc      960

gagauggagc agguggugga gguguacgag uacgcccaga agcugggcgg cgaggccggc     1020

uucuaccaca uccugaacaa ccccaaggcc agccugcuga gccugaccca guucccccac     1080

uucagcagcg uggugcuggg caacgccgcc ggccugggca ucaugggcga guacagaggc     1140

acccccagaa accaggaccu guacgacgcc gccaaggccu acgccgagca gcugaaggag     1200

aacggcguga ucaacuacag cgugcuggac cugaccgccg aggagcugga ggccaucaag     1260

caccagcuga accccaagga caacgacgug gagcugugag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10420
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10420
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggccc ugagcaaggu gaaacucaac gacacccuga auaaggauca gcuucugucc      180

ucuagcaaau acacaaucca aagauccacg ggcgacucua uugauacccc caacuaugac      240

guccagaagc acaucaauaa acucugcggg augcugcuua uuacagagga ugcuaaccau      300

aaguucaccg gacugaucgg caugcucuac gccaugagcc ggcuggggcg cgaagacaca      360

auuaagaucc ugagagaugc gggauaucac guuaaagcua auggcgugga cgugaccaca      420

caucggcagg auaucaacgg gaaggagaug aaauuugaag uccucacccu ggccucccuu      480

acgaccgaga uucagaucaa uauugaaauc gagucucgca agagcuacaa aaagaugcug      540

aaggagaugg gagaaguggc cccugaguau agacacgacu ccccggauug uggcaugauu      600

auccucugca uugcugcccu gguuaucaca aaacuugcug ccggcgaccg gagcgggcug      660

accgcgguga uccgcagagc caacaauguc cucaagaacg aaaugaaacg guacaaggga      720

cugcugccca aagauauugc uaauucuuuc uaugaggugu uugagaagca uccucacuuc      780

aucgacguuu uugugcacuu cggcauugcc caauccagca cacgcggggg aucuagaguc      840

gaaggcaucu uugcuggacu cuucaugaac gccuacgggg cgggccaggu gaugcugcgg      900

uggggcgugc uugccaaauc cgucaagaau auuaugcugg ggcaugcuag cguucaggcc      960

gagauggaac agguggugga ggucuacgaa uaugcucaaa agcucggagg cgaggccggg     1020

uuuuaccaca uccugaacaa ucccaaagcc ucucuucugu cccucaccca guucccucau     1080

uuuagcuccg ugguucuggg aaacgcugcg ggccugggga ucaugggaga guaucgcggc     1140

acgcccagaa accaggaccu cuacgaugcc gcuaaggccu augccgaaca gcugaaagag     1200

aauggcguga uuaacuacuc uguccuugac cugacagcug aggaacucga agccaucaag     1260

caccaacuga auccuaaaga uaacgacgug gagcuuugag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10421
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10421
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac uaagcaaagu caaauuaaac gacacauuaa acaaagacca acucuuauca      180

ucaucaaaau acacaauaca aagaagcacc ggagacagua ucgacacacc aaacuaugac      240

guccaaaaac auauaaauaa auuaugcggc augcucuuaa ucacagaaga cgccaaccau      300

aaauuuacag gauuaauagg aauguuauau gcaaugucac gacuagguag agaagacaca      360

auaaaaauac uaagagacgc aggcuaucac guaaaagcaa auggaguaga cguaaccaca      420

cacagacaag acauaaaugg aaaagaaaug aaauuugaag uauuaacacu agcaucacua      480

acaacagaaa uacaaaucaa cauagaaaua gaaucaagaa aaagcuacaa aaaaauguua      540

aaagaaaugg gagaagucgc accagaauau agacaugauu caccagacug cggaaugaua      600

auacuaugca uagcagcccu aguaauuaca aaacuagcag caggagacag aagcggauua      660

acagcaguaa uaagaagagc aaacaacgua cuaaaaaacg aaaugaaaag auauaaagga      720

uuauuaccaa aagacauagc aaacucauuc uaugaaguau ucgaaaaaca cccccacuuu      780

auagacgucu ucguacacuu cggaauagcc caaucaucca caagaggagg aucaagaguc      840

gaaggaauau ucgcaggauu auucaugaac gcauauggcg caggacaagu aaugcuaaga      900

uggggaguac uagcaaaauc cgucaaaaac auaaugcuag gacacgcauc aguucaagca      960

gaaauggaac aaguaguaga aguauacgaa uacgcccaaa aacuaggagg agaagcagga     1020

uucuaccaca uacuaaauaa uccaaaagca ucacuacuaa gccuaaccca auuuccccac     1080

uucucaagug uaguauuagg aaaugcagcu ggacuaggaa uaaugggaga auacagagga     1140

acaccaagaa accaagacuu auacgacgca gcaaaagcau acgcagagca acuuaaagaa     1200

aacggaguaa uaaacuauag cguacuagac uuaacagcag aagaacugga agcaauaaaa     1260

caucaauuaa acccgaaaga caaugacgua gaauuauaag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10422
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10422
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggcac ucucgaaagu aaaacucaac gacacccuca acaaagacca acuccuuucc      180

agcuccaaau acaccaucca acgauccacc ggagacucca ucgacacgcc caacuacgac      240

guccagaaac acaucaacaa gcucugcgga augcuacuaa ucaccgagga cgccaaccac      300

aaauucacag gacuuauagg gaugcucuac gccauguccc gccucggacg cgaagacaca      360

auaaaaaucc uacgagacgc cggcuaccac guaaaggcaa acggcgucga cgucaccaca      420

cacagacaag acaucaacgg aaaggaaaug aaauucgaag uccucacccu cgccagccua      480

accaccgaga uccaaaucaa caucgaaauc gaaucacgca aauccuacaa gaaaaugcuc      540

aaagaaaugg gagaagucgc ccccgaauac cgucacgacu cgcccgacug cggcaugaua      600

auccuaugca ucgccgcacu cgucauaacc aaacucgccg ccggugaccg aucaggacug      660

acagcaguca uccgccgagc aaacaacgug cucaaaaacg aaaugaaacg cuacaaaggc      720

cuacucccca aagacaucgc caacuccuuc uacgaagucu ucgaaaaaca cccacacuuc      780

aucgacgucu ucguccacuu cggcaucgca caaucaucaa ccagaggcgg cagccgcguu      840

gaaggcaucu ucgcaggacu cuuuaugaac gccuacggcg ccggccaagu caugcuccgc      900

uggggcgucc uggcaaaaag cgucaaaaac aucaugcuag gccacgcuag cguccaagcc      960

gaaauggaac aagucgucga aguuuacgag uacgcacaaa aacucggcgg cgaagcaggc     1020

uucuaccaca uccuaaacaa ccccaaagcc ucccugcuau cacucaccca auucccccac     1080

uucuccagcg ucguccucgg caacgccgca ggacuaggca ucaugggaga auaccgcggg     1140

acaccgcgca accaagaccu cuacgacgcc gccaaagccu acgccgaaca acucaaagaa     1200

aacggcguca uaaacuacuc aguccucgac cucaccgccg aagaacucga agccaucaaa     1260

caccaacuca acccaaaaga caacgacguc gaauuauaag gacuaguaau aaggaaacug     1320

uaugaauguc ugugggcagg aagugaagag auccuucugu aaagguuuuu ggaauuaugu     1380

cugcugaaua auaaacuuuu uugaaauaau aaaucuggua gaaaaaugag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10423
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10423
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcucuuag caaagucaag      120

uugaaugaua cacucaacaa agaucaacuu cugucaucca gcaaauacac cauccaacgg      180

agcacaggag auaguauuga uacuccuaau uaugaugugc agaaacacau caauaaguua      240

uguggcaugu uauuaaucac agaagaugcu aaucauaaau ucacuggguu aauagguaug      300

uuauaugcga ugucuagguu aggaagagaa gacaccauaa aaauacucag agaugcggga      360

uaucauguaa aagcaaaugg aguagaugua acaacacauc gucaagacau uaauggaaaa      420

gaaaugaaau uugaaguguu aacauuggca agcuuaacaa cugaaauuca aaucaacauu      480

gagauagaau cuagaaaauc cuacaaaaaa augcuaaaag aaaugggaga gguagcucca      540

gaauacaggc augacucucc ugauuguggg augauaauau uauguauagc agcauuagua      600

auaacuaaau uagcagcagg ggacagaucu ggucuuacag ccgugauuag gagagcuaau      660

aauguccuaa aaaaugaaau gaaacguuac aaaggcuuac uacccaagga cauagccaac      720

agcuucuaug aaguguuuga aaaacauccc cacuuuauag auguuuuugu ucauuuuggu      780

auagcacaau cuucuaccag agguggcagu agaguugaag ggauuuuugc aggauuguuu      840

augaaugccu auggugcagg gcaagugaug uuacgguggg gagucuuagc aaaaucaguu      900

aaaaauauua uguuaggaca ugcuagugug caagcagaaa uggaacaagu uguugagguu      960

uaugaauaug cccaaaaauu ggguggugaa gcaggauucu accauauauu gaacaaccca     1020

aaagcaucau uauuaucuuu gacucaauuu ccucacuucu ccaguguagu auuaggcaau     1080

gcugcuggcc uaggcauaau gggagaguac agagguacac cgaggaauca agaucuauau     1140

gaugcagcaa aggcauaugc ugaacaacuc aaagaaaaug gugugauuaa cuacagugua     1200

cuagacuuga cagcagaaga acuagaggcu aucaaacauc agcuuaaucc aaaagauaau     1260

gauguagagc uuugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10424
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10424
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cucaacgaca cccugaacaa ggaccagcug cucuccagcu ccaaguacac cauccagcgc      180

agcaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcug      240

ugcgggaugc ugcucaucac cgaggacgcc aaccacaagu ucaccggccu gaucgggaug      300

cuguacgcga ugagccggcu cggccgcgag gacacgauca agauccugcg ggacgccggg      360

uaccacguga aggccaacgg cguggacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccucgcc ucccugacga ccgagaucca gaucaacauc      480

gagaucgaga gccggaaguc cuacaagaag augcugaagg agauggggga gguggccccg      540

gaguaccgcc acgacagccc cgacugcggc augaucaucc ucugcaucgc ggcccugguc      600

aucaccaagc uggccgccgg ggaccggucc ggccucaccg cggugauccg ccgggccaac      660

aacgugcuga agaacgagau gaagcgcuac aaggggcugc uccccaagga caucgccaac      720

agcuucuacg aggucuucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccagu ccagcacgcg gggcgggucc cgcgucgagg gcaucuucgc cgggcuguuc      840

augaacgcgu acggcgccgg ccaggugaug cugcgguggg gcgugcucgc caagagcguc      900

aagaacauca ugcuggggca cgccuccgug caggccgaga uggagcaggu cguggaggug      960

uacgaguacg cgcagaagcu cgggggcgag gccggguucu accacauccu gaacaacccg     1020

aaggccagcc ugcugucccu cacccaguuc ccccacuuca gcagcguggu ccugggcaac     1080

gccgccggcc uggggaucau gggcgaguac cgcgggacgc cccggaacca ggaccucuac     1140

gacgcggcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacuccgug     1200

cuggaccuca ccgccgagga gcuggaggcg aucaagcacc agcugaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10425
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10425
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccucuc caaggucaag      120

cucaacgaca cccucaacaa ggaccagcuc cucuccuccu ccaaguacac cauccagcgc      180

uccaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcuc      240

ugcggcaugc uccucaucac cgaggacgcc aaccacaagu ucaccggccu caucggcaug      300

cucuacgcca ugucccgccu cggccgcgag gacaccauca agauccuccg cgacgccggc      360

uaccacguca aggccaacgg cgucgacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgagguccu cacccucgcc ucccucacca ccgagaucca gaucaacauc      480

gagaucgagu cccgcaaguc cuacaagaag augcucaagg agaugggcga ggucgccccc      540

gaguaccgcc acgacucccc cgacugcggc augaucaucc ucugcaucgc cgcccucguc      600

aucaccaagc ucgccgccgg cgaccgcucc ggccucaccg ccgucauccg ccgcgccaac      660

aacguccuca agaacgagau gaagcgcuac aagggccucc uccccaagga caucgccaac      720

uccuucuacg aggucuucga gaagcacccc cacuucaucg acgucuucgu ccacuucggc      780

aucgcccagu ccuccacccg cggcggcucc cgcgucgagg gcaucuucgc cggccucuuc      840

augaacgccu acggcgccgg ccaggucaug cuccgcuggg gcguccucgc caaguccguc      900

aagaacauca ugcucggcca cgccuccguc caggccgaga uggagcaggu cgucgagguc      960

uacgaguacg cccagaagcu cggcggcgag gccggcuucu accacauccu caacaacccc     1020

aaggccuccc uccucucccu cacccaguuc ccccacuucu ccuccgucgu ccucggcaac     1080

gccgccggcc ucggcaucau gggcgaguac cgcggcaccc cccgcaacca ggaccucuac     1140

gacgccgcca aggccuacgc cgagcagcuc aaggagaacg gcgucaucaa cuacuccguc     1200

cucgaccuca ccgccgagga gcucgaggcc aucaagcacc agcucaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10426
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10426
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccuuaauaa ggaucagcug uuguccucuu caaaauacac aauccaaaga      180

aguacuggcg acagcauuga uacgcccaac uaugacgucc agaagcacau aaauaaauua      240

ugcgggaugc ugcuaaucac cgaggaugcu aaccauaagu ucacaggacu cauugguaug      300

cuguacgcaa uguccaggcu uggccgggaa gacacuauca agauucugcg cgaugccggg      360

uaucacguua aagcgaaugg aguggacgua accacacauc gacaggauau caacggcaag      420

gagaugaaau uugaaguguu gacccucgcu ucucugacua cagagauaca gaucaauauu      480

gaaaucgagu cgcguaaguc auacaaaaag augcugaagg agauggguga agucgccccu      540

gaguauagac acgacagccc agauuguggg augauuaucc ucugcauagc agccuuagug      600

auuaccaaac uggcugcagg agacaggagu ggccuuacgg ccguuauccg gcgcgcuaac      660

aauguguuga agaacgaaau gaaaagauac aagggccugc uaccgaaaga uauugccaau      720

uccuucuaug aggucuuuga gaagcauccc cacuucaucg acguguuugu acacuucggg      780

aucgcgcaau cuagcacuag gggagguucc cggguugaag gcauuuuugc aggacucuuc      840

augaacgccu acggggcugg ccaggugaug cugcgcuggg guguccuugc caaaucagug      900

aagaauauaa ugcuggggca ugcaagugug caggcugaga uggaacaggu cguugaggug      960

uacgaauaug cccaaaaguu gggaggcgag gcgggcuuuu accacauccu caacaauccu     1020

aaagccagcc uguuaucucu gacccaguuc ccacauuuuu ccucaguagu gcucgggaac     1080

gcagcuggac uugguauuau gggcgaguau cgagggacac ccagaaacca ggaccuguac     1140

gaugccgcua aggccuaugc agaacaguug aaagagaaug gagucaucaa cuacagcgug     1200

cuagaccuga cugccgagga acucgaagcu auaaagcacc aacugaaucc uaaagauaac     1260

gacguugagc uuugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10427
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10427
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cugaacgaca cccugaacaa ggaccagcug cugagcagca gcaaguacac cauccagaga      180

agcaccggcg acagcaucga cacccccaac uacgacgugc agaagcacau caacaagcug      240

ugcggcaugc ugcugaucac cgaggacgcc aaccacaagu ucaccggccu gaucggcaug      300

cuguacgcca ugagcagacu gggcagagag gacaccauca agauccugag agacgccggc      360

uaccacguga aggccaacgg cguggacgug accacccaca gacaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccuggcc agccugacca ccgagaucca gaucaacauc      480

gagaucgaga gcagaaagag cuacaagaag augcugaagg agaugggcga gguggccccc      540

gaguacagac acgacagccc cgacugcggc augaucaucc ugugcaucgc cgcccuggug      600

aucaccaagc uggccgccgg cgacagaagc ggccugaccg ccgugaucag aagagccaac      660

aacgugcuga agaacgagau gaagagauac aagggccugc ugcccaagga caucgccaac      720

agcuucuacg agguguucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccaga gcagcaccag aggcggcagc agaguggagg gcaucuucgc cggccuguuc      840

augaacgccu acggcgccgg ccaggugaug cugagauggg gcgugcuggc caagagcgug      900

aagaacauca ugcugggcca cgccagcgug caggccgaga uggagcaggu gguggaggug      960

uacgaguacg cccagaagcu gggcggcgag gccggcuucu accacauccu gaacaacccc     1020

aaggccagcc ugcugagccu gacccaguuc ccccacuuca gcagcguggu gcugggcaac     1080

gccgccggcc ugggcaucau gggcgaguac agaggcaccc ccagaaacca ggaccuguac     1140

gacgccgcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacagcgug     1200

cuggaccuga ccgccgagga gcuggaggcc aucaagcacc agcugaaccc caaggacaac     1260

gacguggagc ugugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10428
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10428
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccugaauaa ggaucagcuu cuguccucua gcaaauacac aauccaaaga      180

uccacgggcg acucuauuga uacccccaac uaugacgucc agaagcacau caauaaacuc      240

ugcgggaugc ugcuuauuac agaggaugcu aaccauaagu ucaccggacu gaucggcaug      300

cucuacgcca ugagccggcu ggggcgcgaa gacacaauua agauccugag agaugcggga      360

uaucacguua aagcuaaugg cguggacgug accacacauc ggcaggauau caacgggaag      420

gagaugaaau uugaaguccu cacccuggcc ucccuuacga ccgagauuca gaucaauauu      480

gaaaucgagu cucgcaagag cuacaaaaag augcugaagg agaugggaga aguggccccu      540

gaguauagac acgacucccc ggauuguggc augauuaucc ucugcauugc ugcccugguu      600

aucacaaaac uugcugccgg cgaccggagc gggcugaccg cggugauccg cagagccaac      660

aauguccuca agaacgaaau gaaacgguac aagggacugc ugcccaaaga uauugcuaau      720

ucuuucuaug agguguuuga gaagcauccu cacuucaucg acguuuuugu gcacuucggc      780

auugcccaau ccagcacacg cgggggaucu agagucgaag gcaucuuugc uggacucuuc      840

augaacgccu acggggcggg ccaggugaug cugcgguggg gcgugcuugc caaauccguc      900

aagaauauua ugcuggggca ugcuagcguu caggccgaga uggaacaggu gguggagguc      960

uacgaauaug cucaaaagcu cggaggcgag gccggguuuu accacauccu gaacaauccc     1020

aaagccucuc uucugucccu cacccaguuc ccucauuuua gcuccguggu ucugggaaac     1080

gcugcgggcc uggggaucau gggagaguau cgcggcacgc ccagaaacca ggaccucuac     1140

gaugccgcua aggccuaugc cgaacagcug aaagagaaug gcgugauuaa cuacucuguc     1200

cuugaccuga cagcugagga acucgaagcc aucaagcacc aacugaaucc uaaagauaac     1260

gacguggagc uuugaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10429
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10429
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacuaag caaagucaaa      120

uuaaacgaca cauuaaacaa agaccaacuc uuaucaucau caaaauacac aauacaaaga      180

agcaccggag acaguaucga cacaccaaac uaugacgucc aaaaacauau aaauaaauua      240

ugcggcaugc ucuuaaucac agaagacgcc aaccauaaau uuacaggauu aauaggaaug      300

uuauaugcaa ugucacgacu agguagagaa gacacaauaa aaauacuaag agacgcaggc      360

uaucacguaa aagcaaaugg aguagacgua accacacaca gacaagacau aaauggaaaa      420

gaaaugaaau uugaaguauu aacacuagca ucacuaacaa cagaaauaca aaucaacaua      480

gaaauagaau caagaaaaag cuacaaaaaa auguuaaaag aaaugggaga agucgcacca      540

gaauauagac augauucacc agacugcgga augauaauac uaugcauagc agcccuagua      600

auuacaaaac uagcagcagg agacagaagc ggauuaacag caguaauaag aagagcaaac      660

aacguacuaa aaaacgaaau gaaaagauau aaaggauuau uaccaaaaga cauagcaaac      720

ucauucuaug aaguauucga aaaacacccc cacuuuauag acgucuucgu acacuucgga      780

auagcccaau cauccacaag aggaggauca agagucgaag gaauauucgc aggauuauuc      840

augaacgcau auggcgcagg acaaguaaug cuaagauggg gaguacuagc aaaauccguc      900

aaaaacauaa ugcuaggaca cgcaucaguu caagcagaaa uggaacaagu aguagaagua      960

uacgaauacg cccaaaaacu aggaggagaa gcaggauucu accacauacu aaauaaucca     1020

aaagcaucac uacuaagccu aacccaauuu ccccacuucu caaguguagu auuaggaaau     1080

gcagcuggac uaggaauaau gggagaauac agaggaacac caagaaacca agacuuauac     1140

gacgcagcaa aagcauacgc agagcaacuu aaagaaaacg gaguaauaaa cuauagcgua     1200

cuagacuuaa cagcagaaga acuggaagca auaaaacauc aauuaaaccc gaaagacaau     1260

gacguagaau uauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10430
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10430
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacucuc gaaaguaaaa      120

cucaacgaca cccucaacaa agaccaacuc cuuuccagcu ccaaauacac cauccaacga      180

uccaccggag acuccaucga cacgcccaac uacgacgucc agaaacacau caacaagcuc      240

ugcggaaugc uacuaaucac cgaggacgcc aaccacaaau ucacaggacu uauagggaug      300

cucuacgcca ugucccgccu cggacgcgaa gacacaauaa aaauccuacg agacgccggc      360

uaccacguaa aggcaaacgg cgucgacguc accacacaca gacaagacau caacggaaag      420

gaaaugaaau ucgaaguccu cacccucgcc agccuaacca ccgagaucca aaucaacauc      480

gaaaucgaau cacgcaaauc cuacaagaaa augcucaaag aaaugggaga agucgccccc      540

gaauaccguc acgacucgcc cgacugcggc augauaaucc uaugcaucgc cgcacucguc      600

auaaccaaac ucgccgccgg ugaccgauca ggacugacag cagucauccg ccgagcaaac      660

aacgugcuca aaaacgaaau gaaacgcuac aaaggccuac uccccaaaga caucgccaac      720

uccuucuacg aagucuucga aaaacaccca cacuucaucg acgucuucgu ccacuucggc      780

aucgcacaau caucaaccag aggcggcagc cgcguugaag gcaucuucgc aggacucuuu      840

augaacgccu acggcgccgg ccaagucaug cuccgcuggg gcguccuggc aaaaagcguc      900

aaaaacauca ugcuaggcca cgcuagcguc caagccgaaa uggaacaagu cgucgaaguu      960

uacgaguacg cacaaaaacu cggcggcgaa gcaggcuucu accacauccu aaacaacccc     1020

aaagccuccc ugcuaucacu cacccaauuc ccccacuucu ccagcgucgu ccucggcaac     1080

gccgcaggac uaggcaucau gggagaauac cgcgggacac cgcgcaacca agaccucuac     1140

gacgccgcca aagccuacgc cgaacaacuc aaagaaaacg gcgucauaaa cuacucaguc     1200

cucgaccuca ccgccgaaga acucgaagcc aucaaacacc aacucaaccc aaaagacaac     1260

gacgucgaau uauaaggacu aguaauaagg aaacuguaug aaugucugug ggcaggaagu     1320

gaagagaucc uucuguaaag guuuuuggaa uuaugucugc ugaauaauaa acuuuuuuga     1380

aauaauaaau cugguagaaa aaugagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1500

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1538


<210>  10431
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10431
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcucuuag caaagucaag      120

uugaaugaua cacucaacaa agaucaacuu cugucaucca gcaaauacac cauccaacgg      180

agcacaggag auaguauuga uacuccuaau uaugaugugc agaaacacau caauaaguua      240

uguggcaugu uauuaaucac agaagaugcu aaucauaaau ucacuggguu aauagguaug      300

uuauaugcga ugucuagguu aggaagagaa gacaccauaa aaauacucag agaugcggga      360

uaucauguaa aagcaaaugg aguagaugua acaacacauc gucaagacau uaauggaaaa      420

gaaaugaaau uugaaguguu aacauuggca agcuuaacaa cugaaauuca aaucaacauu      480

gagauagaau cuagaaaauc cuacaaaaaa augcuaaaag aaaugggaga gguagcucca      540

gaauacaggc augacucucc ugauuguggg augauaauau uauguauagc agcauuagua      600

auaacuaaau uagcagcagg ggacagaucu ggucuuacag ccgugauuag gagagcuaau      660

aauguccuaa aaaaugaaau gaaacguuac aaaggcuuac uacccaagga cauagccaac      720

agcuucuaug aaguguuuga aaaacauccc cacuuuauag auguuuuugu ucauuuuggu      780

auagcacaau cuucuaccag agguggcagu agaguugaag ggauuuuugc aggauuguuu      840

augaaugccu auggugcagg gcaagugaug uuacgguggg gagucuuagc aaaaucaguu      900

aaaaauauua uguuaggaca ugcuagugug caagcagaaa uggaacaagu uguugagguu      960

uaugaauaug cccaaaaauu ggguggugaa gcaggauucu accauauauu gaacaaccca     1020

aaagcaucau uauuaucuuu gacucaauuu ccucacuucu ccaguguagu auuaggcaau     1080

gcugcuggcc uaggcauaau gggagaguac agagguacac cgaggaauca agaucuauau     1140

gaugcagcaa aggcauaugc ugaacaacuc aaagaaaaug gugugauuaa cuacagugua     1200

cuagacuuga cagcagaaga acuagaggcu aucaaacauc agcuuaaucc aaaagauaau     1260

gauguagagc uuugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10432
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10432
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cucaacgaca cccugaacaa ggaccagcug cucuccagcu ccaaguacac cauccagcgc      180

agcaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcug      240

ugcgggaugc ugcucaucac cgaggacgcc aaccacaagu ucaccggccu gaucgggaug      300

cuguacgcga ugagccggcu cggccgcgag gacacgauca agauccugcg ggacgccggg      360

uaccacguga aggccaacgg cguggacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccucgcc ucccugacga ccgagaucca gaucaacauc      480

gagaucgaga gccggaaguc cuacaagaag augcugaagg agauggggga gguggccccg      540

gaguaccgcc acgacagccc cgacugcggc augaucaucc ucugcaucgc ggcccugguc      600

aucaccaagc uggccgccgg ggaccggucc ggccucaccg cggugauccg ccgggccaac      660

aacgugcuga agaacgagau gaagcgcuac aaggggcugc uccccaagga caucgccaac      720

agcuucuacg aggucuucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccagu ccagcacgcg gggcgggucc cgcgucgagg gcaucuucgc cgggcuguuc      840

augaacgcgu acggcgccgg ccaggugaug cugcgguggg gcgugcucgc caagagcguc      900

aagaacauca ugcuggggca cgccuccgug caggccgaga uggagcaggu cguggaggug      960

uacgaguacg cgcagaagcu cgggggcgag gccggguucu accacauccu gaacaacccg     1020

aaggccagcc ugcugucccu cacccaguuc ccccacuuca gcagcguggu ccugggcaac     1080

gccgccggcc uggggaucau gggcgaguac cgcgggacgc cccggaacca ggaccucuac     1140

gacgcggcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacuccgug     1200

cuggaccuca ccgccgagga gcuggaggcg aucaagcacc agcugaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10433
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10433
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccucuc caaggucaag      120

cucaacgaca cccucaacaa ggaccagcuc cucuccuccu ccaaguacac cauccagcgc      180

uccaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcuc      240

ugcggcaugc uccucaucac cgaggacgcc aaccacaagu ucaccggccu caucggcaug      300

cucuacgcca ugucccgccu cggccgcgag gacaccauca agauccuccg cgacgccggc      360

uaccacguca aggccaacgg cgucgacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgagguccu cacccucgcc ucccucacca ccgagaucca gaucaacauc      480

gagaucgagu cccgcaaguc cuacaagaag augcucaagg agaugggcga ggucgccccc      540

gaguaccgcc acgacucccc cgacugcggc augaucaucc ucugcaucgc cgcccucguc      600

aucaccaagc ucgccgccgg cgaccgcucc ggccucaccg ccgucauccg ccgcgccaac      660

aacguccuca agaacgagau gaagcgcuac aagggccucc uccccaagga caucgccaac      720

uccuucuacg aggucuucga gaagcacccc cacuucaucg acgucuucgu ccacuucggc      780

aucgcccagu ccuccacccg cggcggcucc cgcgucgagg gcaucuucgc cggccucuuc      840

augaacgccu acggcgccgg ccaggucaug cuccgcuggg gcguccucgc caaguccguc      900

aagaacauca ugcucggcca cgccuccguc caggccgaga uggagcaggu cgucgagguc      960

uacgaguacg cccagaagcu cggcggcgag gccggcuucu accacauccu caacaacccc     1020

aaggccuccc uccucucccu cacccaguuc ccccacuucu ccuccgucgu ccucggcaac     1080

gccgccggcc ucggcaucau gggcgaguac cgcggcaccc cccgcaacca ggaccucuac     1140

gacgccgcca aggccuacgc cgagcagcuc aaggagaacg gcgucaucaa cuacuccguc     1200

cucgaccuca ccgccgagga gcucgaggcc aucaagcacc agcucaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10434
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10434
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccuuaauaa ggaucagcug uuguccucuu caaaauacac aauccaaaga      180

aguacuggcg acagcauuga uacgcccaac uaugacgucc agaagcacau aaauaaauua      240

ugcgggaugc ugcuaaucac cgaggaugcu aaccauaagu ucacaggacu cauugguaug      300

cuguacgcaa uguccaggcu uggccgggaa gacacuauca agauucugcg cgaugccggg      360

uaucacguua aagcgaaugg aguggacgua accacacauc gacaggauau caacggcaag      420

gagaugaaau uugaaguguu gacccucgcu ucucugacua cagagauaca gaucaauauu      480

gaaaucgagu cgcguaaguc auacaaaaag augcugaagg agauggguga agucgccccu      540

gaguauagac acgacagccc agauuguggg augauuaucc ucugcauagc agccuuagug      600

auuaccaaac uggcugcagg agacaggagu ggccuuacgg ccguuauccg gcgcgcuaac      660

aauguguuga agaacgaaau gaaaagauac aagggccugc uaccgaaaga uauugccaau      720

uccuucuaug aggucuuuga gaagcauccc cacuucaucg acguguuugu acacuucggg      780

aucgcgcaau cuagcacuag gggagguucc cggguugaag gcauuuuugc aggacucuuc      840

augaacgccu acggggcugg ccaggugaug cugcgcuggg guguccuugc caaaucagug      900

aagaauauaa ugcuggggca ugcaagugug caggcugaga uggaacaggu cguugaggug      960

uacgaauaug cccaaaaguu gggaggcgag gcgggcuuuu accacauccu caacaauccu     1020

aaagccagcc uguuaucucu gacccaguuc ccacauuuuu ccucaguagu gcucgggaac     1080

gcagcuggac uugguauuau gggcgaguau cgagggacac ccagaaacca ggaccuguac     1140

gaugccgcua aggccuaugc agaacaguug aaagagaaug gagucaucaa cuacagcgug     1200

cuagaccuga cugccgagga acucgaagcu auaaagcacc aacugaaucc uaaagauaac     1260

gacguugagc uuugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10435
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10435
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cugaacgaca cccugaacaa ggaccagcug cugagcagca gcaaguacac cauccagaga      180

agcaccggcg acagcaucga cacccccaac uacgacgugc agaagcacau caacaagcug      240

ugcggcaugc ugcugaucac cgaggacgcc aaccacaagu ucaccggccu gaucggcaug      300

cuguacgcca ugagcagacu gggcagagag gacaccauca agauccugag agacgccggc      360

uaccacguga aggccaacgg cguggacgug accacccaca gacaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccuggcc agccugacca ccgagaucca gaucaacauc      480

gagaucgaga gcagaaagag cuacaagaag augcugaagg agaugggcga gguggccccc      540

gaguacagac acgacagccc cgacugcggc augaucaucc ugugcaucgc cgcccuggug      600

aucaccaagc uggccgccgg cgacagaagc ggccugaccg ccgugaucag aagagccaac      660

aacgugcuga agaacgagau gaagagauac aagggccugc ugcccaagga caucgccaac      720

agcuucuacg agguguucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccaga gcagcaccag aggcggcagc agaguggagg gcaucuucgc cggccuguuc      840

augaacgccu acggcgccgg ccaggugaug cugagauggg gcgugcuggc caagagcgug      900

aagaacauca ugcugggcca cgccagcgug caggccgaga uggagcaggu gguggaggug      960

uacgaguacg cccagaagcu gggcggcgag gccggcuucu accacauccu gaacaacccc     1020

aaggccagcc ugcugagccu gacccaguuc ccccacuuca gcagcguggu gcugggcaac     1080

gccgccggcc ugggcaucau gggcgaguac agaggcaccc ccagaaacca ggaccuguac     1140

gacgccgcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacagcgug     1200

cuggaccuga ccgccgagga gcuggaggcc aucaagcacc agcugaaccc caaggacaac     1260

gacguggagc ugugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10436
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10436
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccugaauaa ggaucagcuu cuguccucua gcaaauacac aauccaaaga      180

uccacgggcg acucuauuga uacccccaac uaugacgucc agaagcacau caauaaacuc      240

ugcgggaugc ugcuuauuac agaggaugcu aaccauaagu ucaccggacu gaucggcaug      300

cucuacgcca ugagccggcu ggggcgcgaa gacacaauua agauccugag agaugcggga      360

uaucacguua aagcuaaugg cguggacgug accacacauc ggcaggauau caacgggaag      420

gagaugaaau uugaaguccu cacccuggcc ucccuuacga ccgagauuca gaucaauauu      480

gaaaucgagu cucgcaagag cuacaaaaag augcugaagg agaugggaga aguggccccu      540

gaguauagac acgacucccc ggauuguggc augauuaucc ucugcauugc ugcccugguu      600

aucacaaaac uugcugccgg cgaccggagc gggcugaccg cggugauccg cagagccaac      660

aauguccuca agaacgaaau gaaacgguac aagggacugc ugcccaaaga uauugcuaau      720

ucuuucuaug agguguuuga gaagcauccu cacuucaucg acguuuuugu gcacuucggc      780

auugcccaau ccagcacacg cgggggaucu agagucgaag gcaucuuugc uggacucuuc      840

augaacgccu acggggcggg ccaggugaug cugcgguggg gcgugcuugc caaauccguc      900

aagaauauua ugcuggggca ugcuagcguu caggccgaga uggaacaggu gguggagguc      960

uacgaauaug cucaaaagcu cggaggcgag gccggguuuu accacauccu gaacaauccc     1020

aaagccucuc uucugucccu cacccaguuc ccucauuuua gcuccguggu ucugggaaac     1080

gcugcgggcc uggggaucau gggagaguau cgcggcacgc ccagaaacca ggaccucuac     1140

gaugccgcua aggccuaugc cgaacagcug aaagagaaug gcgugauuaa cuacucuguc     1200

cuugaccuga cagcugagga acucgaagcc aucaagcacc aacugaaucc uaaagauaac     1260

gacguggagc uuugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10437
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10437
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacuaag caaagucaaa      120

uuaaacgaca cauuaaacaa agaccaacuc uuaucaucau caaaauacac aauacaaaga      180

agcaccggag acaguaucga cacaccaaac uaugacgucc aaaaacauau aaauaaauua      240

ugcggcaugc ucuuaaucac agaagacgcc aaccauaaau uuacaggauu aauaggaaug      300

uuauaugcaa ugucacgacu agguagagaa gacacaauaa aaauacuaag agacgcaggc      360

uaucacguaa aagcaaaugg aguagacgua accacacaca gacaagacau aaauggaaaa      420

gaaaugaaau uugaaguauu aacacuagca ucacuaacaa cagaaauaca aaucaacaua      480

gaaauagaau caagaaaaag cuacaaaaaa auguuaaaag aaaugggaga agucgcacca      540

gaauauagac augauucacc agacugcgga augauaauac uaugcauagc agcccuagua      600

auuacaaaac uagcagcagg agacagaagc ggauuaacag caguaauaag aagagcaaac      660

aacguacuaa aaaacgaaau gaaaagauau aaaggauuau uaccaaaaga cauagcaaac      720

ucauucuaug aaguauucga aaaacacccc cacuuuauag acgucuucgu acacuucgga      780

auagcccaau cauccacaag aggaggauca agagucgaag gaauauucgc aggauuauuc      840

augaacgcau auggcgcagg acaaguaaug cuaagauggg gaguacuagc aaaauccguc      900

aaaaacauaa ugcuaggaca cgcaucaguu caagcagaaa uggaacaagu aguagaagua      960

uacgaauacg cccaaaaacu aggaggagaa gcaggauucu accacauacu aaauaaucca     1020

aaagcaucac uacuaagccu aacccaauuu ccccacuucu caaguguagu auuaggaaau     1080

gcagcuggac uaggaauaau gggagaauac agaggaacac caagaaacca agacuuauac     1140

gacgcagcaa aagcauacgc agagcaacuu aaagaaaacg gaguaauaaa cuauagcgua     1200

cuagacuuaa cagcagaaga acuggaagca auaaaacauc aauuaaaccc gaaagacaau     1260

gacguagaau uauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10438
<211>  1554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10438
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacucuc gaaaguaaaa      120

cucaacgaca cccucaacaa agaccaacuc cuuuccagcu ccaaauacac cauccaacga      180

uccaccggag acuccaucga cacgcccaac uacgacgucc agaaacacau caacaagcuc      240

ugcggaaugc uacuaaucac cgaggacgcc aaccacaaau ucacaggacu uauagggaug      300

cucuacgcca ugucccgccu cggacgcgaa gacacaauaa aaauccuacg agacgccggc      360

uaccacguaa aggcaaacgg cgucgacguc accacacaca gacaagacau caacggaaag      420

gaaaugaaau ucgaaguccu cacccucgcc agccuaacca ccgagaucca aaucaacauc      480

gaaaucgaau cacgcaaauc cuacaagaaa augcucaaag aaaugggaga agucgccccc      540

gaauaccguc acgacucgcc cgacugcggc augauaaucc uaugcaucgc cgcacucguc      600

auaaccaaac ucgccgccgg ugaccgauca ggacugacag cagucauccg ccgagcaaac      660

aacgugcuca aaaacgaaau gaaacgcuac aaaggccuac uccccaaaga caucgccaac      720

uccuucuacg aagucuucga aaaacaccca cacuucaucg acgucuucgu ccacuucggc      780

aucgcacaau caucaaccag aggcggcagc cgcguugaag gcaucuucgc aggacucuuu      840

augaacgccu acggcgccgg ccaagucaug cuccgcuggg gcguccuggc aaaaagcguc      900

aaaaacauca ugcuaggcca cgcuagcguc caagccgaaa uggaacaagu cgucgaaguu      960

uacgaguacg cacaaaaacu cggcggcgaa gcaggcuucu accacauccu aaacaacccc     1020

aaagccuccc ugcuaucacu cacccaauuc ccccacuucu ccagcgucgu ccucggcaac     1080

gccgcaggac uaggcaucau gggagaauac cgcgggacac cgcgcaacca agaccucuac     1140

gacgccgcca aagccuacgc cgaacaacuc aaagaaaacg gcgucauaaa cuacucaguc     1200

cucgaccuca ccgccgaaga acucgaagcc aucaaacacc aacucaaccc aaaagacaac     1260

gacgucgaau uauaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu     1320

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc     1380

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1500

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1554


<210>  10439
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10439
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcucuuag caaagucaag      120

uugaaugaua cacucaacaa agaucaacuu cugucaucca gcaaauacac cauccaacgg      180

agcacaggag auaguauuga uacuccuaau uaugaugugc agaaacacau caauaaguua      240

uguggcaugu uauuaaucac agaagaugcu aaucauaaau ucacuggguu aauagguaug      300

uuauaugcga ugucuagguu aggaagagaa gacaccauaa aaauacucag agaugcggga      360

uaucauguaa aagcaaaugg aguagaugua acaacacauc gucaagacau uaauggaaaa      420

gaaaugaaau uugaaguguu aacauuggca agcuuaacaa cugaaauuca aaucaacauu      480

gagauagaau cuagaaaauc cuacaaaaaa augcuaaaag aaaugggaga gguagcucca      540

gaauacaggc augacucucc ugauuguggg augauaauau uauguauagc agcauuagua      600

auaacuaaau uagcagcagg ggacagaucu ggucuuacag ccgugauuag gagagcuaau      660

aauguccuaa aaaaugaaau gaaacguuac aaaggcuuac uacccaagga cauagccaac      720

agcuucuaug aaguguuuga aaaacauccc cacuuuauag auguuuuugu ucauuuuggu      780

auagcacaau cuucuaccag agguggcagu agaguugaag ggauuuuugc aggauuguuu      840

augaaugccu auggugcagg gcaagugaug uuacgguggg gagucuuagc aaaaucaguu      900

aaaaauauua uguuaggaca ugcuagugug caagcagaaa uggaacaagu uguugagguu      960

uaugaauaug cccaaaaauu ggguggugaa gcaggauucu accauauauu gaacaaccca     1020

aaagcaucau uauuaucuuu gacucaauuu ccucacuucu ccaguguagu auuaggcaau     1080

gcugcuggcc uaggcauaau gggagaguac agagguacac cgaggaauca agaucuauau     1140

gaugcagcaa aggcauaugc ugaacaacuc aaagaaaaug gugugauuaa cuacagugua     1200

cuagacuuga cagcagaaga acuagaggcu aucaaacauc agcuuaaucc aaaagauaau     1260

gauguagagc uuugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10440
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10440
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cucaacgaca cccugaacaa ggaccagcug cucuccagcu ccaaguacac cauccagcgc      180

agcaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcug      240

ugcgggaugc ugcucaucac cgaggacgcc aaccacaagu ucaccggccu gaucgggaug      300

cuguacgcga ugagccggcu cggccgcgag gacacgauca agauccugcg ggacgccggg      360

uaccacguga aggccaacgg cguggacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccucgcc ucccugacga ccgagaucca gaucaacauc      480

gagaucgaga gccggaaguc cuacaagaag augcugaagg agauggggga gguggccccg      540

gaguaccgcc acgacagccc cgacugcggc augaucaucc ucugcaucgc ggcccugguc      600

aucaccaagc uggccgccgg ggaccggucc ggccucaccg cggugauccg ccgggccaac      660

aacgugcuga agaacgagau gaagcgcuac aaggggcugc uccccaagga caucgccaac      720

agcuucuacg aggucuucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccagu ccagcacgcg gggcgggucc cgcgucgagg gcaucuucgc cgggcuguuc      840

augaacgcgu acggcgccgg ccaggugaug cugcgguggg gcgugcucgc caagagcguc      900

aagaacauca ugcuggggca cgccuccgug caggccgaga uggagcaggu cguggaggug      960

uacgaguacg cgcagaagcu cgggggcgag gccggguucu accacauccu gaacaacccg     1020

aaggccagcc ugcugucccu cacccaguuc ccccacuuca gcagcguggu ccugggcaac     1080

gccgccggcc uggggaucau gggcgaguac cgcgggacgc cccggaacca ggaccucuac     1140

gacgcggcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacuccgug     1200

cuggaccuca ccgccgagga gcuggaggcg aucaagcacc agcugaaccc caaggacaac     1260

gacgucgagc ucugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10441
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10441
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccucuc caaggucaag      120

cucaacgaca cccucaacaa ggaccagcuc cucuccuccu ccaaguacac cauccagcgc      180

uccaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcuc      240

ugcggcaugc uccucaucac cgaggacgcc aaccacaagu ucaccggccu caucggcaug      300

cucuacgcca ugucccgccu cggccgcgag gacaccauca agauccuccg cgacgccggc      360

uaccacguca aggccaacgg cgucgacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgagguccu cacccucgcc ucccucacca ccgagaucca gaucaacauc      480

gagaucgagu cccgcaaguc cuacaagaag augcucaagg agaugggcga ggucgccccc      540

gaguaccgcc acgacucccc cgacugcggc augaucaucc ucugcaucgc cgcccucguc      600

aucaccaagc ucgccgccgg cgaccgcucc ggccucaccg ccgucauccg ccgcgccaac      660

aacguccuca agaacgagau gaagcgcuac aagggccucc uccccaagga caucgccaac      720

uccuucuacg aggucuucga gaagcacccc cacuucaucg acgucuucgu ccacuucggc      780

aucgcccagu ccuccacccg cggcggcucc cgcgucgagg gcaucuucgc cggccucuuc      840

augaacgccu acggcgccgg ccaggucaug cuccgcuggg gcguccucgc caaguccguc      900

aagaacauca ugcucggcca cgccuccguc caggccgaga uggagcaggu cgucgagguc      960

uacgaguacg cccagaagcu cggcggcgag gccggcuucu accacauccu caacaacccc     1020

aaggccuccc uccucucccu cacccaguuc ccccacuucu ccuccgucgu ccucggcaac     1080

gccgccggcc ucggcaucau gggcgaguac cgcggcaccc cccgcaacca ggaccucuac     1140

gacgccgcca aggccuacgc cgagcagcuc aaggagaacg gcgucaucaa cuacuccguc     1200

cucgaccuca ccgccgagga gcucgaggcc aucaagcacc agcucaaccc caaggacaac     1260

gacgucgagc ucugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10442
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10442
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccuuaauaa ggaucagcug uuguccucuu caaaauacac aauccaaaga      180

aguacuggcg acagcauuga uacgcccaac uaugacgucc agaagcacau aaauaaauua      240

ugcgggaugc ugcuaaucac cgaggaugcu aaccauaagu ucacaggacu cauugguaug      300

cuguacgcaa uguccaggcu uggccgggaa gacacuauca agauucugcg cgaugccggg      360

uaucacguua aagcgaaugg aguggacgua accacacauc gacaggauau caacggcaag      420

gagaugaaau uugaaguguu gacccucgcu ucucugacua cagagauaca gaucaauauu      480

gaaaucgagu cgcguaaguc auacaaaaag augcugaagg agauggguga agucgccccu      540

gaguauagac acgacagccc agauuguggg augauuaucc ucugcauagc agccuuagug      600

auuaccaaac uggcugcagg agacaggagu ggccuuacgg ccguuauccg gcgcgcuaac      660

aauguguuga agaacgaaau gaaaagauac aagggccugc uaccgaaaga uauugccaau      720

uccuucuaug aggucuuuga gaagcauccc cacuucaucg acguguuugu acacuucggg      780

aucgcgcaau cuagcacuag gggagguucc cggguugaag gcauuuuugc aggacucuuc      840

augaacgccu acggggcugg ccaggugaug cugcgcuggg guguccuugc caaaucagug      900

aagaauauaa ugcuggggca ugcaagugug caggcugaga uggaacaggu cguugaggug      960

uacgaauaug cccaaaaguu gggaggcgag gcgggcuuuu accacauccu caacaauccu     1020

aaagccagcc uguuaucucu gacccaguuc ccacauuuuu ccucaguagu gcucgggaac     1080

gcagcuggac uugguauuau gggcgaguau cgagggacac ccagaaacca ggaccuguac     1140

gaugccgcua aggccuaugc agaacaguug aaagagaaug gagucaucaa cuacagcgug     1200

cuagaccuga cugccgagga acucgaagcu auaaagcacc aacugaaucc uaaagauaac     1260

gacguugagc uuugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10443
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10443
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cugaacgaca cccugaacaa ggaccagcug cugagcagca gcaaguacac cauccagaga      180

agcaccggcg acagcaucga cacccccaac uacgacgugc agaagcacau caacaagcug      240

ugcggcaugc ugcugaucac cgaggacgcc aaccacaagu ucaccggccu gaucggcaug      300

cuguacgcca ugagcagacu gggcagagag gacaccauca agauccugag agacgccggc      360

uaccacguga aggccaacgg cguggacgug accacccaca gacaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccuggcc agccugacca ccgagaucca gaucaacauc      480

gagaucgaga gcagaaagag cuacaagaag augcugaagg agaugggcga gguggccccc      540

gaguacagac acgacagccc cgacugcggc augaucaucc ugugcaucgc cgcccuggug      600

aucaccaagc uggccgccgg cgacagaagc ggccugaccg ccgugaucag aagagccaac      660

aacgugcuga agaacgagau gaagagauac aagggccugc ugcccaagga caucgccaac      720

agcuucuacg agguguucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccaga gcagcaccag aggcggcagc agaguggagg gcaucuucgc cggccuguuc      840

augaacgccu acggcgccgg ccaggugaug cugagauggg gcgugcuggc caagagcgug      900

aagaacauca ugcugggcca cgccagcgug caggccgaga uggagcaggu gguggaggug      960

uacgaguacg cccagaagcu gggcggcgag gccggcuucu accacauccu gaacaacccc     1020

aaggccagcc ugcugagccu gacccaguuc ccccacuuca gcagcguggu gcugggcaac     1080

gccgccggcc ugggcaucau gggcgaguac agaggcaccc ccagaaacca ggaccuguac     1140

gacgccgcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacagcgug     1200

cuggaccuga ccgccgagga gcuggaggcc aucaagcacc agcugaaccc caaggacaac     1260

gacguggagc ugugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10444
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10444
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccugaauaa ggaucagcuu cuguccucua gcaaauacac aauccaaaga      180

uccacgggcg acucuauuga uacccccaac uaugacgucc agaagcacau caauaaacuc      240

ugcgggaugc ugcuuauuac agaggaugcu aaccauaagu ucaccggacu gaucggcaug      300

cucuacgcca ugagccggcu ggggcgcgaa gacacaauua agauccugag agaugcggga      360

uaucacguua aagcuaaugg cguggacgug accacacauc ggcaggauau caacgggaag      420

gagaugaaau uugaaguccu cacccuggcc ucccuuacga ccgagauuca gaucaauauu      480

gaaaucgagu cucgcaagag cuacaaaaag augcugaagg agaugggaga aguggccccu      540

gaguauagac acgacucccc ggauuguggc augauuaucc ucugcauugc ugcccugguu      600

aucacaaaac uugcugccgg cgaccggagc gggcugaccg cggugauccg cagagccaac      660

aauguccuca agaacgaaau gaaacgguac aagggacugc ugcccaaaga uauugcuaau      720

ucuuucuaug agguguuuga gaagcauccu cacuucaucg acguuuuugu gcacuucggc      780

auugcccaau ccagcacacg cgggggaucu agagucgaag gcaucuuugc uggacucuuc      840

augaacgccu acggggcggg ccaggugaug cugcgguggg gcgugcuugc caaauccguc      900

aagaauauua ugcuggggca ugcuagcguu caggccgaga uggaacaggu gguggagguc      960

uacgaauaug cucaaaagcu cggaggcgag gccggguuuu accacauccu gaacaauccc     1020

aaagccucuc uucugucccu cacccaguuc ccucauuuua gcuccguggu ucugggaaac     1080

gcugcgggcc uggggaucau gggagaguau cgcggcacgc ccagaaacca ggaccucuac     1140

gaugccgcua aggccuaugc cgaacagcug aaagagaaug gcgugauuaa cuacucuguc     1200

cuugaccuga cagcugagga acucgaagcc aucaagcacc aacugaaucc uaaagauaac     1260

gacguggagc uuugaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10445
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10445
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacuaag caaagucaaa      120

uuaaacgaca cauuaaacaa agaccaacuc uuaucaucau caaaauacac aauacaaaga      180

agcaccggag acaguaucga cacaccaaac uaugacgucc aaaaacauau aaauaaauua      240

ugcggcaugc ucuuaaucac agaagacgcc aaccauaaau uuacaggauu aauaggaaug      300

uuauaugcaa ugucacgacu agguagagaa gacacaauaa aaauacuaag agacgcaggc      360

uaucacguaa aagcaaaugg aguagacgua accacacaca gacaagacau aaauggaaaa      420

gaaaugaaau uugaaguauu aacacuagca ucacuaacaa cagaaauaca aaucaacaua      480

gaaauagaau caagaaaaag cuacaaaaaa auguuaaaag aaaugggaga agucgcacca      540

gaauauagac augauucacc agacugcgga augauaauac uaugcauagc agcccuagua      600

auuacaaaac uagcagcagg agacagaagc ggauuaacag caguaauaag aagagcaaac      660

aacguacuaa aaaacgaaau gaaaagauau aaaggauuau uaccaaaaga cauagcaaac      720

ucauucuaug aaguauucga aaaacacccc cacuuuauag acgucuucgu acacuucgga      780

auagcccaau cauccacaag aggaggauca agagucgaag gaauauucgc aggauuauuc      840

augaacgcau auggcgcagg acaaguaaug cuaagauggg gaguacuagc aaaauccguc      900

aaaaacauaa ugcuaggaca cgcaucaguu caagcagaaa uggaacaagu aguagaagua      960

uacgaauacg cccaaaaacu aggaggagaa gcaggauucu accacauacu aaauaaucca     1020

aaagcaucac uacuaagccu aacccaauuu ccccacuucu caaguguagu auuaggaaau     1080

gcagcuggac uaggaauaau gggagaauac agaggaacac caagaaacca agacuuauac     1140

gacgcagcaa aagcauacgc agagcaacuu aaagaaaacg gaguaauaaa cuauagcgua     1200

cuagacuuaa cagcagaaga acuggaagca auaaaacauc aauuaaaccc gaaagacaau     1260

gacguagaau uauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10446
<211>  1770
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10446
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacucuc gaaaguaaaa      120

cucaacgaca cccucaacaa agaccaacuc cuuuccagcu ccaaauacac cauccaacga      180

uccaccggag acuccaucga cacgcccaac uacgacgucc agaaacacau caacaagcuc      240

ugcggaaugc uacuaaucac cgaggacgcc aaccacaaau ucacaggacu uauagggaug      300

cucuacgcca ugucccgccu cggacgcgaa gacacaauaa aaauccuacg agacgccggc      360

uaccacguaa aggcaaacgg cgucgacguc accacacaca gacaagacau caacggaaag      420

gaaaugaaau ucgaaguccu cacccucgcc agccuaacca ccgagaucca aaucaacauc      480

gaaaucgaau cacgcaaauc cuacaagaaa augcucaaag aaaugggaga agucgccccc      540

gaauaccguc acgacucgcc cgacugcggc augauaaucc uaugcaucgc cgcacucguc      600

auaaccaaac ucgccgccgg ugaccgauca ggacugacag cagucauccg ccgagcaaac      660

aacgugcuca aaaacgaaau gaaacgcuac aaaggccuac uccccaaaga caucgccaac      720

uccuucuacg aagucuucga aaaacaccca cacuucaucg acgucuucgu ccacuucggc      780

aucgcacaau caucaaccag aggcggcagc cgcguugaag gcaucuucgc aggacucuuu      840

augaacgccu acggcgccgg ccaagucaug cuccgcuggg gcguccuggc aaaaagcguc      900

aaaaacauca ugcuaggcca cgcuagcguc caagccgaaa uggaacaagu cgucgaaguu      960

uacgaguacg cacaaaaacu cggcggcgaa gcaggcuucu accacauccu aaacaacccc     1020

aaagccuccc ugcuaucacu cacccaauuc ccccacuucu ccagcgucgu ccucggcaac     1080

gccgcaggac uaggcaucau gggagaauac cgcgggacac cgcgcaacca agaccucuac     1140

gacgccgcca aagccuacgc cgaacaacuc aaagaaaacg gcgucauaaa cuacucaguc     1200

cucgaccuca ccgccgaaga acucgaagcc aucaaacacc aacucaaccc aaaagacaac     1260

gacgucgaau uauaaggacu agugaaggga acacccaaau uuaauucagc cuuaagcaca     1320

auuaauuaag agugaaacgu aauuguacaa gcaguugguc acccaccaua gggcaugauc     1380

aacaccgcaa ccuuuccuuu uucccccagu gauucugaaa aaccccucuu cccuucagcu     1440

ugcuuagaug uuccaaauuu aguaagcuua aggcggccua cagaagaaaa agaaaaaaaa     1500

ggccacaaaa guucccucuc acuuucagua aauaaaauaa aagcagcaac agaaauaaag     1560

aaauaaauga aauucaaaau gaaauaaaua uuguguugug cagcauuaaa aaaucaauaa     1620

aaauuaaaaa ugagcaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc     1740

ccaaaggcuc uuuucagagc caccagaauu                                      1770


<210>  10447
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10447
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcucuuag caaagucaag      120

uugaaugaua cacucaacaa agaucaacuu cugucaucca gcaaauacac cauccaacgg      180

agcacaggag auaguauuga uacuccuaau uaugaugugc agaaacacau caauaaguua      240

uguggcaugu uauuaaucac agaagaugcu aaucauaaau ucacuggguu aauagguaug      300

uuauaugcga ugucuagguu aggaagagaa gacaccauaa aaauacucag agaugcggga      360

uaucauguaa aagcaaaugg aguagaugua acaacacauc gucaagacau uaauggaaaa      420

gaaaugaaau uugaaguguu aacauuggca agcuuaacaa cugaaauuca aaucaacauu      480

gagauagaau cuagaaaauc cuacaaaaaa augcuaaaag aaaugggaga gguagcucca      540

gaauacaggc augacucucc ugauuguggg augauaauau uauguauagc agcauuagua      600

auaacuaaau uagcagcagg ggacagaucu ggucuuacag ccgugauuag gagagcuaau      660

aauguccuaa aaaaugaaau gaaacguuac aaaggcuuac uacccaagga cauagccaac      720

agcuucuaug aaguguuuga aaaacauccc cacuuuauag auguuuuugu ucauuuuggu      780

auagcacaau cuucuaccag agguggcagu agaguugaag ggauuuuugc aggauuguuu      840

augaaugccu auggugcagg gcaagugaug uuacgguggg gagucuuagc aaaaucaguu      900

aaaaauauua uguuaggaca ugcuagugug caagcagaaa uggaacaagu uguugagguu      960

uaugaauaug cccaaaaauu ggguggugaa gcaggauucu accauauauu gaacaaccca     1020

aaagcaucau uauuaucuuu gacucaauuu ccucacuucu ccaguguagu auuaggcaau     1080

gcugcuggcc uaggcauaau gggagaguac agagguacac cgaggaauca agaucuauau     1140

gaugcagcaa aggcauaugc ugaacaacuc aaagaaaaug gugugauuaa cuacagugua     1200

cuagacuuga cagcagaaga acuagaggcu aucaaacauc agcuuaaucc aaaagauaau     1260

gauguagagc uuugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10448
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10448
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cucaacgaca cccugaacaa ggaccagcug cucuccagcu ccaaguacac cauccagcgc      180

agcaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcug      240

ugcgggaugc ugcucaucac cgaggacgcc aaccacaagu ucaccggccu gaucgggaug      300

cuguacgcga ugagccggcu cggccgcgag gacacgauca agauccugcg ggacgccggg      360

uaccacguga aggccaacgg cguggacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccucgcc ucccugacga ccgagaucca gaucaacauc      480

gagaucgaga gccggaaguc cuacaagaag augcugaagg agauggggga gguggccccg      540

gaguaccgcc acgacagccc cgacugcggc augaucaucc ucugcaucgc ggcccugguc      600

aucaccaagc uggccgccgg ggaccggucc ggccucaccg cggugauccg ccgggccaac      660

aacgugcuga agaacgagau gaagcgcuac aaggggcugc uccccaagga caucgccaac      720

agcuucuacg aggucuucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccagu ccagcacgcg gggcgggucc cgcgucgagg gcaucuucgc cgggcuguuc      840

augaacgcgu acggcgccgg ccaggugaug cugcgguggg gcgugcucgc caagagcguc      900

aagaacauca ugcuggggca cgccuccgug caggccgaga uggagcaggu cguggaggug      960

uacgaguacg cgcagaagcu cgggggcgag gccggguucu accacauccu gaacaacccg     1020

aaggccagcc ugcugucccu cacccaguuc ccccacuuca gcagcguggu ccugggcaac     1080

gccgccggcc uggggaucau gggcgaguac cgcgggacgc cccggaacca ggaccucuac     1140

gacgcggcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacuccgug     1200

cuggaccuca ccgccgagga gcuggaggcg aucaagcacc agcugaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10449
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10449
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccucuc caaggucaag      120

cucaacgaca cccucaacaa ggaccagcuc cucuccuccu ccaaguacac cauccagcgc      180

uccaccggcg acuccaucga cacccccaac uacgacgucc agaagcacau caacaagcuc      240

ugcggcaugc uccucaucac cgaggacgcc aaccacaagu ucaccggccu caucggcaug      300

cucuacgcca ugucccgccu cggccgcgag gacaccauca agauccuccg cgacgccggc      360

uaccacguca aggccaacgg cgucgacguc accacccacc gccaggacau caacggcaag      420

gagaugaagu ucgagguccu cacccucgcc ucccucacca ccgagaucca gaucaacauc      480

gagaucgagu cccgcaaguc cuacaagaag augcucaagg agaugggcga ggucgccccc      540

gaguaccgcc acgacucccc cgacugcggc augaucaucc ucugcaucgc cgcccucguc      600

aucaccaagc ucgccgccgg cgaccgcucc ggccucaccg ccgucauccg ccgcgccaac      660

aacguccuca agaacgagau gaagcgcuac aagggccucc uccccaagga caucgccaac      720

uccuucuacg aggucuucga gaagcacccc cacuucaucg acgucuucgu ccacuucggc      780

aucgcccagu ccuccacccg cggcggcucc cgcgucgagg gcaucuucgc cggccucuuc      840

augaacgccu acggcgccgg ccaggucaug cuccgcuggg gcguccucgc caaguccguc      900

aagaacauca ugcucggcca cgccuccguc caggccgaga uggagcaggu cgucgagguc      960

uacgaguacg cccagaagcu cggcggcgag gccggcuucu accacauccu caacaacccc     1020

aaggccuccc uccucucccu cacccaguuc ccccacuucu ccuccgucgu ccucggcaac     1080

gccgccggcc ucggcaucau gggcgaguac cgcggcaccc cccgcaacca ggaccucuac     1140

gacgccgcca aggccuacgc cgagcagcuc aaggagaacg gcgucaucaa cuacuccguc     1200

cucgaccuca ccgccgagga gcucgaggcc aucaagcacc agcucaaccc caaggacaac     1260

gacgucgagc ucugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10450
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10450
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccuuaauaa ggaucagcug uuguccucuu caaaauacac aauccaaaga      180

aguacuggcg acagcauuga uacgcccaac uaugacgucc agaagcacau aaauaaauua      240

ugcgggaugc ugcuaaucac cgaggaugcu aaccauaagu ucacaggacu cauugguaug      300

cuguacgcaa uguccaggcu uggccgggaa gacacuauca agauucugcg cgaugccggg      360

uaucacguua aagcgaaugg aguggacgua accacacauc gacaggauau caacggcaag      420

gagaugaaau uugaaguguu gacccucgcu ucucugacua cagagauaca gaucaauauu      480

gaaaucgagu cgcguaaguc auacaaaaag augcugaagg agauggguga agucgccccu      540

gaguauagac acgacagccc agauuguggg augauuaucc ucugcauagc agccuuagug      600

auuaccaaac uggcugcagg agacaggagu ggccuuacgg ccguuauccg gcgcgcuaac      660

aauguguuga agaacgaaau gaaaagauac aagggccugc uaccgaaaga uauugccaau      720

uccuucuaug aggucuuuga gaagcauccc cacuucaucg acguguuugu acacuucggg      780

aucgcgcaau cuagcacuag gggagguucc cggguugaag gcauuuuugc aggacucuuc      840

augaacgccu acggggcugg ccaggugaug cugcgcuggg guguccuugc caaaucagug      900

aagaauauaa ugcuggggca ugcaagugug caggcugaga uggaacaggu cguugaggug      960

uacgaauaug cccaaaaguu gggaggcgag gcgggcuuuu accacauccu caacaauccu     1020

aaagccagcc uguuaucucu gacccaguuc ccacauuuuu ccucaguagu gcucgggaac     1080

gcagcuggac uugguauuau gggcgaguau cgagggacac ccagaaacca ggaccuguac     1140

gaugccgcua aggccuaugc agaacaguug aaagagaaug gagucaucaa cuacagcgug     1200

cuagaccuga cugccgagga acucgaagcu auaaagcacc aacugaaucc uaaagauaac     1260

gacguugagc uuugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10451
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10451
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaag      120

cugaacgaca cccugaacaa ggaccagcug cugagcagca gcaaguacac cauccagaga      180

agcaccggcg acagcaucga cacccccaac uacgacgugc agaagcacau caacaagcug      240

ugcggcaugc ugcugaucac cgaggacgcc aaccacaagu ucaccggccu gaucggcaug      300

cuguacgcca ugagcagacu gggcagagag gacaccauca agauccugag agacgccggc      360

uaccacguga aggccaacgg cguggacgug accacccaca gacaggacau caacggcaag      420

gagaugaagu ucgaggugcu gacccuggcc agccugacca ccgagaucca gaucaacauc      480

gagaucgaga gcagaaagag cuacaagaag augcugaagg agaugggcga gguggccccc      540

gaguacagac acgacagccc cgacugcggc augaucaucc ugugcaucgc cgcccuggug      600

aucaccaagc uggccgccgg cgacagaagc ggccugaccg ccgugaucag aagagccaac      660

aacgugcuga agaacgagau gaagagauac aagggccugc ugcccaagga caucgccaac      720

agcuucuacg agguguucga gaagcacccc cacuucaucg acguguucgu gcacuucggc      780

aucgcccaga gcagcaccag aggcggcagc agaguggagg gcaucuucgc cggccuguuc      840

augaacgccu acggcgccgg ccaggugaug cugagauggg gcgugcuggc caagagcgug      900

aagaacauca ugcugggcca cgccagcgug caggccgaga uggagcaggu gguggaggug      960

uacgaguacg cccagaagcu gggcggcgag gccggcuucu accacauccu gaacaacccc     1020

aaggccagcc ugcugagccu gacccaguuc ccccacuuca gcagcguggu gcugggcaac     1080

gccgccggcc ugggcaucau gggcgaguac agaggcaccc ccagaaacca ggaccuguac     1140

gacgccgcca aggccuacgc cgagcagcug aaggagaacg gcgugaucaa cuacagcgug     1200

cuggaccuga ccgccgagga gcuggaggcc aucaagcacc agcugaaccc caaggacaac     1260

gacguggagc ugugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10452
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10452
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcccugag caaggugaaa      120

cucaacgaca cccugaauaa ggaucagcuu cuguccucua gcaaauacac aauccaaaga      180

uccacgggcg acucuauuga uacccccaac uaugacgucc agaagcacau caauaaacuc      240

ugcgggaugc ugcuuauuac agaggaugcu aaccauaagu ucaccggacu gaucggcaug      300

cucuacgcca ugagccggcu ggggcgcgaa gacacaauua agauccugag agaugcggga      360

uaucacguua aagcuaaugg cguggacgug accacacauc ggcaggauau caacgggaag      420

gagaugaaau uugaaguccu cacccuggcc ucccuuacga ccgagauuca gaucaauauu      480

gaaaucgagu cucgcaagag cuacaaaaag augcugaagg agaugggaga aguggccccu      540

gaguauagac acgacucccc ggauuguggc augauuaucc ucugcauugc ugcccugguu      600

aucacaaaac uugcugccgg cgaccggagc gggcugaccg cggugauccg cagagccaac      660

aauguccuca agaacgaaau gaaacgguac aagggacugc ugcccaaaga uauugcuaau      720

ucuuucuaug agguguuuga gaagcauccu cacuucaucg acguuuuugu gcacuucggc      780

auugcccaau ccagcacacg cgggggaucu agagucgaag gcaucuuugc uggacucuuc      840

augaacgccu acggggcggg ccaggugaug cugcgguggg gcgugcuugc caaauccguc      900

aagaauauua ugcuggggca ugcuagcguu caggccgaga uggaacaggu gguggagguc      960

uacgaauaug cucaaaagcu cggaggcgag gccggguuuu accacauccu gaacaauccc     1020

aaagccucuc uucugucccu cacccaguuc ccucauuuua gcuccguggu ucugggaaac     1080

gcugcgggcc uggggaucau gggagaguau cgcggcacgc ccagaaacca ggaccucuac     1140

gaugccgcua aggccuaugc cgaacagcug aaagagaaug gcgugauuaa cuacucuguc     1200

cuugaccuga cagcugagga acucgaagcc aucaagcacc aacugaaucc uaaagauaac     1260

gacguggagc uuugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10453
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10453
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacuaag caaagucaaa      120

uuaaacgaca cauuaaacaa agaccaacuc uuaucaucau caaaauacac aauacaaaga      180

agcaccggag acaguaucga cacaccaaac uaugacgucc aaaaacauau aaauaaauua      240

ugcggcaugc ucuuaaucac agaagacgcc aaccauaaau uuacaggauu aauaggaaug      300

uuauaugcaa ugucacgacu agguagagaa gacacaauaa aaauacuaag agacgcaggc      360

uaucacguaa aagcaaaugg aguagacgua accacacaca gacaagacau aaauggaaaa      420

gaaaugaaau uugaaguauu aacacuagca ucacuaacaa cagaaauaca aaucaacaua      480

gaaauagaau caagaaaaag cuacaaaaaa auguuaaaag aaaugggaga agucgcacca      540

gaauauagac augauucacc agacugcgga augauaauac uaugcauagc agcccuagua      600

auuacaaaac uagcagcagg agacagaagc ggauuaacag caguaauaag aagagcaaac      660

aacguacuaa aaaacgaaau gaaaagauau aaaggauuau uaccaaaaga cauagcaaac      720

ucauucuaug aaguauucga aaaacacccc cacuuuauag acgucuucgu acacuucgga      780

auagcccaau cauccacaag aggaggauca agagucgaag gaauauucgc aggauuauuc      840

augaacgcau auggcgcagg acaaguaaug cuaagauggg gaguacuagc aaaauccguc      900

aaaaacauaa ugcuaggaca cgcaucaguu caagcagaaa uggaacaagu aguagaagua      960

uacgaauacg cccaaaaacu aggaggagaa gcaggauucu accacauacu aaauaaucca     1020

aaagcaucac uacuaagccu aacccaauuu ccccacuucu caaguguagu auuaggaaau     1080

gcagcuggac uaggaauaau gggagaauac agaggaacac caagaaacca agacuuauac     1140

gacgcagcaa aagcauacgc agagcaacuu aaagaaaacg gaguaauaaa cuauagcgua     1200

cuagacuuaa cagcagaaga acuggaagca auaaaacauc aauuaaaccc gaaagacaau     1260

gacguagaau uauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10454
<211>  1550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10454
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggcacucuc gaaaguaaaa      120

cucaacgaca cccucaacaa agaccaacuc cuuuccagcu ccaaauacac cauccaacga      180

uccaccggag acuccaucga cacgcccaac uacgacgucc agaaacacau caacaagcuc      240

ugcggaaugc uacuaaucac cgaggacgcc aaccacaaau ucacaggacu uauagggaug      300

cucuacgcca ugucccgccu cggacgcgaa gacacaauaa aaauccuacg agacgccggc      360

uaccacguaa aggcaaacgg cgucgacguc accacacaca gacaagacau caacggaaag      420

gaaaugaaau ucgaaguccu cacccucgcc agccuaacca ccgagaucca aaucaacauc      480

gaaaucgaau cacgcaaauc cuacaagaaa augcucaaag aaaugggaga agucgccccc      540

gaauaccguc acgacucgcc cgacugcggc augauaaucc uaugcaucgc cgcacucguc      600

auaaccaaac ucgccgccgg ugaccgauca ggacugacag cagucauccg ccgagcaaac      660

aacgugcuca aaaacgaaau gaaacgcuac aaaggccuac uccccaaaga caucgccaac      720

uccuucuacg aagucuucga aaaacaccca cacuucaucg acgucuucgu ccacuucggc      780

aucgcacaau caucaaccag aggcggcagc cgcguugaag gcaucuucgc aggacucuuu      840

augaacgccu acggcgccgg ccaagucaug cuccgcuggg gcguccuggc aaaaagcguc      900

aaaaacauca ugcuaggcca cgcuagcguc caagccgaaa uggaacaagu cgucgaaguu      960

uacgaguacg cacaaaaacu cggcggcgaa gcaggcuucu accacauccu aaacaacccc     1020

aaagccuccc ugcuaucacu cacccaauuc ccccacuucu ccagcgucgu ccucggcaac     1080

gccgcaggac uaggcaucau gggagaauac cgcgggacac cgcgcaacca agaccucuac     1140

gacgccgcca aagccuacgc cgaacaacuc aaagaaaacg gcgucauaaa cuacucaguc     1200

cucgaccuca ccgccgaaga acucgaagcc aucaaacacc aacucaaccc aaaagacaac     1260

gacgucgaau uauaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca     1320

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu     1380

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1500

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1550


<210>  10455
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10455
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcu      180

cuuagcaaag ucaaguugaa ugauacacuc aacaaagauc aacuucuguc auccagcaaa      240

uacaccaucc aacggagcac aggagauagu auugauacuc cuaauuauga ugugcagaaa      300

cacaucaaua aguuaugugg cauguuauua aucacagaag augcuaauca uaaauucacu      360

ggguuaauag guauguuaua ugcgaugucu agguuaggaa gagaagacac cauaaaaaua      420

cucagagaug cgggauauca uguaaaagca aauggaguag auguaacaac acaucgucaa      480

gacauuaaug gaaaagaaau gaaauuugaa guguuaacau uggcaagcuu aacaacugaa      540

auucaaauca acauugagau agaaucuaga aaauccuaca aaaaaaugcu aaaagaaaug      600

ggagagguag cuccagaaua caggcaugac ucuccugauu gugggaugau aauauuaugu      660

auagcagcau uaguaauaac uaaauuagca gcaggggaca gaucuggucu uacagccgug      720

auuaggagag cuaauaaugu ccuaaaaaau gaaaugaaac guuacaaagg cuuacuaccc      780

aaggacauag ccaacagcuu cuaugaagug uuugaaaaac auccccacuu uauagauguu      840

uuuguucauu uugguauagc acaaucuucu accagaggug gcaguagagu ugaagggauu      900

uuugcaggau uguuuaugaa ugccuauggu gcagggcaag ugauguuacg guggggaguc      960

uuagcaaaau caguuaaaaa uauuauguua ggacaugcua gugugcaagc agaaauggaa     1020

caaguuguug agguuuauga auaugcccaa aaauugggug gugaagcagg auucuaccau     1080

auauugaaca acccaaaagc aucauuauua ucuuugacuc aauuuccuca cuucuccagu     1140

guaguauuag gcaaugcugc uggccuaggc auaaugggag aguacagagg uacaccgagg     1200

aaucaagauc uauaugaugc agcaaaggca uaugcugaac aacucaaaga aaauggugug     1260

auuaacuaca guguacuaga cuugacagca gaagaacuag aggcuaucaa acaucagcuu     1320

aauccaaaag auaaugaugu agagcuuuga ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10456
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10456
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcucaa cgacacccug aacaaggacc agcugcucuc cagcuccaag      240

uacaccaucc agcgcagcac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcugugcgg gaugcugcuc aucaccgagg acgccaacca caaguucacc      360

ggccugaucg ggaugcugua cgcgaugagc cggcucggcc gcgaggacac gaucaagauc      420

cugcgggacg ccggguacca cgugaaggcc aacggcgugg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc ucgccucccu gacgaccgag      540

auccagauca acaucgagau cgagagccgg aaguccuaca agaagaugcu gaaggagaug      600

ggggaggugg ccccggagua ccgccacgac agccccgacu gcggcaugau cauccucugc      660

aucgcggccc uggucaucac caagcuggcc gccggggacc gguccggccu caccgcggug      720

auccgccggg ccaacaacgu gcugaagaac gagaugaagc gcuacaaggg gcugcucccc      780

aaggacaucg ccaacagcuu cuacgagguc uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccaguccagc acgcggggcg ggucccgcgu cgagggcauc      900

uucgccgggc uguucaugaa cgcguacggc gccggccagg ugaugcugcg guggggcgug      960

cucgccaaga gcgucaagaa caucaugcug gggcacgccu ccgugcaggc cgagauggag     1020

caggucgugg agguguacga guacgcgcag aagcucgggg gcgaggccgg guucuaccac     1080

auccugaaca acccgaaggc cagccugcug ucccucaccc aguuccccca cuucagcagc     1140

gugguccugg gcaacgccgc cggccugggg aucaugggcg aguaccgcgg gacgccccgg     1200

aaccaggacc ucuacgacgc ggccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuacu ccgugcugga ccucaccgcc gaggagcugg aggcgaucaa gcaccagcug     1320

aaccccaagg acaacgacgu cgagcucuga ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10457
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10457
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cucuccaagg ucaagcucaa cgacacccuc aacaaggacc agcuccucuc cuccuccaag      240

uacaccaucc agcgcuccac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcucugcgg caugcuccuc aucaccgagg acgccaacca caaguucacc      360

ggccucaucg gcaugcucua cgccaugucc cgccucggcc gcgaggacac caucaagauc      420

cuccgcgacg ccggcuacca cgucaaggcc aacggcgucg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag guccucaccc ucgccucccu caccaccgag      540

auccagauca acaucgagau cgagucccgc aaguccuaca agaagaugcu caaggagaug      600

ggcgaggucg cccccgagua ccgccacgac ucccccgacu gcggcaugau cauccucugc      660

aucgccgccc ucgucaucac caagcucgcc gccggcgacc gcuccggccu caccgccguc      720

auccgccgcg ccaacaacgu ccucaagaac gagaugaagc gcuacaaggg ccuccucccc      780

aaggacaucg ccaacuccuu cuacgagguc uucgagaagc acccccacuu caucgacguc      840

uucguccacu ucggcaucgc ccaguccucc acccgcggcg gcucccgcgu cgagggcauc      900

uucgccggcc ucuucaugaa cgccuacggc gccggccagg ucaugcuccg cuggggcguc      960

cucgccaagu ccgucaagaa caucaugcuc ggccacgccu ccguccaggc cgagauggag     1020

caggucgucg aggucuacga guacgcccag aagcucggcg gcgaggccgg cuucuaccac     1080

auccucaaca accccaaggc cucccuccuc ucccucaccc aguuccccca cuucuccucc     1140

gucguccucg gcaacgccgc cggccucggc aucaugggcg aguaccgcgg caccccccgc     1200

aaccaggacc ucuacgacgc cgccaaggcc uacgccgagc agcucaagga gaacggcguc     1260

aucaacuacu ccguccucga ccucaccgcc gaggagcucg aggccaucaa gcaccagcuc     1320

aaccccaagg acaacgacgu cgagcucuga ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10458
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10458
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccuu aauaaggauc agcuguuguc cucuucaaaa      240

uacacaaucc aaagaaguac uggcgacagc auugauacgc ccaacuauga cguccagaag      300

cacauaaaua aauuaugcgg gaugcugcua aucaccgagg augcuaacca uaaguucaca      360

ggacucauug guaugcugua cgcaaugucc aggcuuggcc gggaagacac uaucaagauu      420

cugcgcgaug ccggguauca cguuaaagcg aauggagugg acguaaccac acaucgacag      480

gauaucaacg gcaaggagau gaaauuugaa guguugaccc ucgcuucucu gacuacagag      540

auacagauca auauugaaau cgagucgcgu aagucauaca aaaagaugcu gaaggagaug      600

ggugaagucg ccccugagua uagacacgac agcccagauu gugggaugau uauccucugc      660

auagcagccu uagugauuac caaacuggcu gcaggagaca ggaguggccu uacggccguu      720

auccggcgcg cuaacaaugu guugaagaac gaaaugaaaa gauacaaggg ccugcuaccg      780

aaagauauug ccaauuccuu cuaugagguc uuugagaagc auccccacuu caucgacgug      840

uuuguacacu ucgggaucgc gcaaucuagc acuaggggag guucccgggu ugaaggcauu      900

uuugcaggac ucuucaugaa cgccuacggg gcuggccagg ugaugcugcg cugggguguc      960

cuugccaaau cagugaagaa uauaaugcug gggcaugcaa gugugcaggc ugagauggaa     1020

caggucguug agguguacga auaugcccaa aaguugggag gcgaggcggg cuuuuaccac     1080

auccucaaca auccuaaagc cagccuguua ucucugaccc aguucccaca uuuuuccuca     1140

guagugcucg ggaacgcagc uggacuuggu auuaugggcg aguaucgagg gacacccaga     1200

aaccaggacc uguacgaugc cgcuaaggcc uaugcagaac aguugaaaga gaauggaguc     1260

aucaacuaca gcgugcuaga ccugacugcc gaggaacucg aagcuauaaa gcaccaacug     1320

aauccuaaag auaacgacgu ugagcuuuga ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10459
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10459
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcugaa cgacacccug aacaaggacc agcugcugag cagcagcaag      240

uacaccaucc agagaagcac cggcgacagc aucgacaccc ccaacuacga cgugcagaag      300

cacaucaaca agcugugcgg caugcugcug aucaccgagg acgccaacca caaguucacc      360

ggccugaucg gcaugcugua cgccaugagc agacugggca gagaggacac caucaagauc      420

cugagagacg ccggcuacca cgugaaggcc aacggcgugg acgugaccac ccacagacag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc uggccagccu gaccaccgag      540

auccagauca acaucgagau cgagagcaga aagagcuaca agaagaugcu gaaggagaug      600

ggcgaggugg cccccgagua cagacacgac agccccgacu gcggcaugau cauccugugc      660

aucgccgccc uggugaucac caagcuggcc gccggcgaca gaagcggccu gaccgccgug      720

aucagaagag ccaacaacgu gcugaagaac gagaugaaga gauacaaggg ccugcugccc      780

aaggacaucg ccaacagcuu cuacgaggug uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccagagcagc accagaggcg gcagcagagu ggagggcauc      900

uucgccggcc uguucaugaa cgccuacggc gccggccagg ugaugcugag auggggcgug      960

cuggccaaga gcgugaagaa caucaugcug ggccacgcca gcgugcaggc cgagauggag     1020

cagguggugg agguguacga guacgcccag aagcugggcg gcgaggccgg cuucuaccac     1080

auccugaaca accccaaggc cagccugcug agccugaccc aguuccccca cuucagcagc     1140

guggugcugg gcaacgccgc cggccugggc aucaugggcg aguacagagg cacccccaga     1200

aaccaggacc uguacgacgc cgccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuaca gcgugcugga ccugaccgcc gaggagcugg aggccaucaa gcaccagcug     1320

aaccccaagg acaacgacgu ggagcuguga ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10460
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10460
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccug aauaaggauc agcuucuguc cucuagcaaa      240

uacacaaucc aaagauccac gggcgacucu auugauaccc ccaacuauga cguccagaag      300

cacaucaaua aacucugcgg gaugcugcuu auuacagagg augcuaacca uaaguucacc      360

ggacugaucg gcaugcucua cgccaugagc cggcuggggc gcgaagacac aauuaagauc      420

cugagagaug cgggauauca cguuaaagcu aauggcgugg acgugaccac acaucggcag      480

gauaucaacg ggaaggagau gaaauuugaa guccucaccc uggccucccu uacgaccgag      540

auucagauca auauugaaau cgagucucgc aagagcuaca aaaagaugcu gaaggagaug      600

ggagaagugg ccccugagua uagacacgac uccccggauu guggcaugau uauccucugc      660

auugcugccc ugguuaucac aaaacuugcu gccggcgacc ggagcgggcu gaccgcggug      720

auccgcagag ccaacaaugu ccucaagaac gaaaugaaac gguacaaggg acugcugccc      780

aaagauauug cuaauucuuu cuaugaggug uuugagaagc auccucacuu caucgacguu      840

uuugugcacu ucggcauugc ccaauccagc acacgcgggg gaucuagagu cgaaggcauc      900

uuugcuggac ucuucaugaa cgccuacggg gcgggccagg ugaugcugcg guggggcgug      960

cuugccaaau ccgucaagaa uauuaugcug gggcaugcua gcguucaggc cgagauggaa     1020

cagguggugg aggucuacga auaugcucaa aagcucggag gcgaggccgg guuuuaccac     1080

auccugaaca aucccaaagc cucucuucug ucccucaccc aguucccuca uuuuagcucc     1140

gugguucugg gaaacgcugc gggccugggg aucaugggag aguaucgcgg cacgcccaga     1200

aaccaggacc ucuacgaugc cgcuaaggcc uaugccgaac agcugaaaga gaauggcgug     1260

auuaacuacu cuguccuuga ccugacagcu gaggaacucg aagccaucaa gcaccaacug     1320

aauccuaaag auaacgacgu ggagcuuuga ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10461
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10461
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cuaagcaaag ucaaauuaaa cgacacauua aacaaagacc aacucuuauc aucaucaaaa      240

uacacaauac aaagaagcac cggagacagu aucgacacac caaacuauga cguccaaaaa      300

cauauaaaua aauuaugcgg caugcucuua aucacagaag acgccaacca uaaauuuaca      360

ggauuaauag gaauguuaua ugcaauguca cgacuaggua gagaagacac aauaaaaaua      420

cuaagagacg caggcuauca cguaaaagca aauggaguag acguaaccac acacagacaa      480

gacauaaaug gaaaagaaau gaaauuugaa guauuaacac uagcaucacu aacaacagaa      540

auacaaauca acauagaaau agaaucaaga aaaagcuaca aaaaaauguu aaaagaaaug      600

ggagaagucg caccagaaua uagacaugau ucaccagacu gcggaaugau aauacuaugc      660

auagcagccc uaguaauuac aaaacuagca gcaggagaca gaagcggauu aacagcagua      720

auaagaagag caaacaacgu acuaaaaaac gaaaugaaaa gauauaaagg auuauuacca      780

aaagacauag caaacucauu cuaugaagua uucgaaaaac acccccacuu uauagacguc      840

uucguacacu ucggaauagc ccaaucaucc acaagaggag gaucaagagu cgaaggaaua      900

uucgcaggau uauucaugaa cgcauauggc gcaggacaag uaaugcuaag auggggagua      960

cuagcaaaau ccgucaaaaa cauaaugcua ggacacgcau caguucaagc agaaauggaa     1020

caaguaguag aaguauacga auacgcccaa aaacuaggag gagaagcagg auucuaccac     1080

auacuaaaua auccaaaagc aucacuacua agccuaaccc aauuucccca cuucucaagu     1140

guaguauuag gaaaugcagc uggacuagga auaaugggag aauacagagg aacaccaaga     1200

aaccaagacu uauacgacgc agcaaaagca uacgcagagc aacuuaaaga aaacggagua     1260

auaaacuaua gcguacuaga cuuaacagca gaagaacugg aagcaauaaa acaucaauua     1320

aacccgaaag acaaugacgu agaauuauaa ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10462
<211>  1613
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10462
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cucucgaaag uaaaacucaa cgacacccuc aacaaagacc aacuccuuuc cagcuccaaa      240

uacaccaucc aacgauccac cggagacucc aucgacacgc ccaacuacga cguccagaaa      300

cacaucaaca agcucugcgg aaugcuacua aucaccgagg acgccaacca caaauucaca      360

ggacuuauag ggaugcucua cgccaugucc cgccucggac gcgaagacac aauaaaaauc      420

cuacgagacg ccggcuacca cguaaaggca aacggcgucg acgucaccac acacagacaa      480

gacaucaacg gaaaggaaau gaaauucgaa guccucaccc ucgccagccu aaccaccgag      540

auccaaauca acaucgaaau cgaaucacgc aaauccuaca agaaaaugcu caaagaaaug      600

ggagaagucg cccccgaaua ccgucacgac ucgcccgacu gcggcaugau aauccuaugc      660

aucgccgcac ucgucauaac caaacucgcc gccggugacc gaucaggacu gacagcaguc      720

auccgccgag caaacaacgu gcucaaaaac gaaaugaaac gcuacaaagg ccuacucccc      780

aaagacaucg ccaacuccuu cuacgaaguc uucgaaaaac acccacacuu caucgacguc      840

uucguccacu ucggcaucgc acaaucauca accagaggcg gcagccgcgu ugaaggcauc      900

uucgcaggac ucuuuaugaa cgccuacggc gccggccaag ucaugcuccg cuggggcguc      960

cuggcaaaaa gcgucaaaaa caucaugcua ggccacgcua gcguccaagc cgaaauggaa     1020

caagucgucg aaguuuacga guacgcacaa aaacucggcg gcgaagcagg cuucuaccac     1080

auccuaaaca accccaaagc cucccugcua ucacucaccc aauuccccca cuucuccagc     1140

gucguccucg gcaacgccgc aggacuaggc aucaugggag aauaccgcgg gacaccgcgc     1200

aaccaagacc ucuacgacgc cgccaaagcc uacgccgaac aacucaaaga aaacggcguc     1260

auaaacuacu caguccucga ccucaccgcc gaagaacucg aagccaucaa acaccaacuc     1320

aacccaaaag acaacgacgu cgaauuauaa ggacuaguaa uaaggaaacu guaugaaugu     1380

cugugggcag gaagugaaga gauccuucug uaaagguuuu uggaauuaug ucugcugaau     1440

aauaaacuuu uuugaaauaa uaaaucuggu agaaaaauga gaucuaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc     1560

cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga auu            1613


<210>  10463
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10463
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcu      180

cuuagcaaag ucaaguugaa ugauacacuc aacaaagauc aacuucuguc auccagcaaa      240

uacaccaucc aacggagcac aggagauagu auugauacuc cuaauuauga ugugcagaaa      300

cacaucaaua aguuaugugg cauguuauua aucacagaag augcuaauca uaaauucacu      360

ggguuaauag guauguuaua ugcgaugucu agguuaggaa gagaagacac cauaaaaaua      420

cucagagaug cgggauauca uguaaaagca aauggaguag auguaacaac acaucgucaa      480

gacauuaaug gaaaagaaau gaaauuugaa guguuaacau uggcaagcuu aacaacugaa      540

auucaaauca acauugagau agaaucuaga aaauccuaca aaaaaaugcu aaaagaaaug      600

ggagagguag cuccagaaua caggcaugac ucuccugauu gugggaugau aauauuaugu      660

auagcagcau uaguaauaac uaaauuagca gcaggggaca gaucuggucu uacagccgug      720

auuaggagag cuaauaaugu ccuaaaaaau gaaaugaaac guuacaaagg cuuacuaccc      780

aaggacauag ccaacagcuu cuaugaagug uuugaaaaac auccccacuu uauagauguu      840

uuuguucauu uugguauagc acaaucuucu accagaggug gcaguagagu ugaagggauu      900

uuugcaggau uguuuaugaa ugccuauggu gcagggcaag ugauguuacg guggggaguc      960

uuagcaaaau caguuaaaaa uauuauguua ggacaugcua gugugcaagc agaaauggaa     1020

caaguuguug agguuuauga auaugcccaa aaauugggug gugaagcagg auucuaccau     1080

auauugaaca acccaaaagc aucauuauua ucuuugacuc aauuuccuca cuucuccagu     1140

guaguauuag gcaaugcugc uggccuaggc auaaugggag aguacagagg uacaccgagg     1200

aaucaagauc uauaugaugc agcaaaggca uaugcugaac aacucaaaga aaauggugug     1260

auuaacuaca guguacuaga cuugacagca gaagaacuag aggcuaucaa acaucagcuu     1320

aauccaaaag auaaugaugu agagcuuuga ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10464
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10464
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcucaa cgacacccug aacaaggacc agcugcucuc cagcuccaag      240

uacaccaucc agcgcagcac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcugugcgg gaugcugcuc aucaccgagg acgccaacca caaguucacc      360

ggccugaucg ggaugcugua cgcgaugagc cggcucggcc gcgaggacac gaucaagauc      420

cugcgggacg ccggguacca cgugaaggcc aacggcgugg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc ucgccucccu gacgaccgag      540

auccagauca acaucgagau cgagagccgg aaguccuaca agaagaugcu gaaggagaug      600

ggggaggugg ccccggagua ccgccacgac agccccgacu gcggcaugau cauccucugc      660

aucgcggccc uggucaucac caagcuggcc gccggggacc gguccggccu caccgcggug      720

auccgccggg ccaacaacgu gcugaagaac gagaugaagc gcuacaaggg gcugcucccc      780

aaggacaucg ccaacagcuu cuacgagguc uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccaguccagc acgcggggcg ggucccgcgu cgagggcauc      900

uucgccgggc uguucaugaa cgcguacggc gccggccagg ugaugcugcg guggggcgug      960

cucgccaaga gcgucaagaa caucaugcug gggcacgccu ccgugcaggc cgagauggag     1020

caggucgugg agguguacga guacgcgcag aagcucgggg gcgaggccgg guucuaccac     1080

auccugaaca acccgaaggc cagccugcug ucccucaccc aguuccccca cuucagcagc     1140

gugguccugg gcaacgccgc cggccugggg aucaugggcg aguaccgcgg gacgccccgg     1200

aaccaggacc ucuacgacgc ggccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuacu ccgugcugga ccucaccgcc gaggagcugg aggcgaucaa gcaccagcug     1320

aaccccaagg acaacgacgu cgagcucuga ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10465
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10465
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cucuccaagg ucaagcucaa cgacacccuc aacaaggacc agcuccucuc cuccuccaag      240

uacaccaucc agcgcuccac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcucugcgg caugcuccuc aucaccgagg acgccaacca caaguucacc      360

ggccucaucg gcaugcucua cgccaugucc cgccucggcc gcgaggacac caucaagauc      420

cuccgcgacg ccggcuacca cgucaaggcc aacggcgucg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag guccucaccc ucgccucccu caccaccgag      540

auccagauca acaucgagau cgagucccgc aaguccuaca agaagaugcu caaggagaug      600

ggcgaggucg cccccgagua ccgccacgac ucccccgacu gcggcaugau cauccucugc      660

aucgccgccc ucgucaucac caagcucgcc gccggcgacc gcuccggccu caccgccguc      720

auccgccgcg ccaacaacgu ccucaagaac gagaugaagc gcuacaaggg ccuccucccc      780

aaggacaucg ccaacuccuu cuacgagguc uucgagaagc acccccacuu caucgacguc      840

uucguccacu ucggcaucgc ccaguccucc acccgcggcg gcucccgcgu cgagggcauc      900

uucgccggcc ucuucaugaa cgccuacggc gccggccagg ucaugcuccg cuggggcguc      960

cucgccaagu ccgucaagaa caucaugcuc ggccacgccu ccguccaggc cgagauggag     1020

caggucgucg aggucuacga guacgcccag aagcucggcg gcgaggccgg cuucuaccac     1080

auccucaaca accccaaggc cucccuccuc ucccucaccc aguuccccca cuucuccucc     1140

gucguccucg gcaacgccgc cggccucggc aucaugggcg aguaccgcgg caccccccgc     1200

aaccaggacc ucuacgacgc cgccaaggcc uacgccgagc agcucaagga gaacggcguc     1260

aucaacuacu ccguccucga ccucaccgcc gaggagcucg aggccaucaa gcaccagcuc     1320

aaccccaagg acaacgacgu cgagcucuga ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10466
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10466
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccuu aauaaggauc agcuguuguc cucuucaaaa      240

uacacaaucc aaagaaguac uggcgacagc auugauacgc ccaacuauga cguccagaag      300

cacauaaaua aauuaugcgg gaugcugcua aucaccgagg augcuaacca uaaguucaca      360

ggacucauug guaugcugua cgcaaugucc aggcuuggcc gggaagacac uaucaagauu      420

cugcgcgaug ccggguauca cguuaaagcg aauggagugg acguaaccac acaucgacag      480

gauaucaacg gcaaggagau gaaauuugaa guguugaccc ucgcuucucu gacuacagag      540

auacagauca auauugaaau cgagucgcgu aagucauaca aaaagaugcu gaaggagaug      600

ggugaagucg ccccugagua uagacacgac agcccagauu gugggaugau uauccucugc      660

auagcagccu uagugauuac caaacuggcu gcaggagaca ggaguggccu uacggccguu      720

auccggcgcg cuaacaaugu guugaagaac gaaaugaaaa gauacaaggg ccugcuaccg      780

aaagauauug ccaauuccuu cuaugagguc uuugagaagc auccccacuu caucgacgug      840

uuuguacacu ucgggaucgc gcaaucuagc acuaggggag guucccgggu ugaaggcauu      900

uuugcaggac ucuucaugaa cgccuacggg gcuggccagg ugaugcugcg cugggguguc      960

cuugccaaau cagugaagaa uauaaugcug gggcaugcaa gugugcaggc ugagauggaa     1020

caggucguug agguguacga auaugcccaa aaguugggag gcgaggcggg cuuuuaccac     1080

auccucaaca auccuaaagc cagccuguua ucucugaccc aguucccaca uuuuuccuca     1140

guagugcucg ggaacgcagc uggacuuggu auuaugggcg aguaucgagg gacacccaga     1200

aaccaggacc uguacgaugc cgcuaaggcc uaugcagaac aguugaaaga gaauggaguc     1260

aucaacuaca gcgugcuaga ccugacugcc gaggaacucg aagcuauaaa gcaccaacug     1320

aauccuaaag auaacgacgu ugagcuuuga ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10467
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10467
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcugaa cgacacccug aacaaggacc agcugcugag cagcagcaag      240

uacaccaucc agagaagcac cggcgacagc aucgacaccc ccaacuacga cgugcagaag      300

cacaucaaca agcugugcgg caugcugcug aucaccgagg acgccaacca caaguucacc      360

ggccugaucg gcaugcugua cgccaugagc agacugggca gagaggacac caucaagauc      420

cugagagacg ccggcuacca cgugaaggcc aacggcgugg acgugaccac ccacagacag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc uggccagccu gaccaccgag      540

auccagauca acaucgagau cgagagcaga aagagcuaca agaagaugcu gaaggagaug      600

ggcgaggugg cccccgagua cagacacgac agccccgacu gcggcaugau cauccugugc      660

aucgccgccc uggugaucac caagcuggcc gccggcgaca gaagcggccu gaccgccgug      720

aucagaagag ccaacaacgu gcugaagaac gagaugaaga gauacaaggg ccugcugccc      780

aaggacaucg ccaacagcuu cuacgaggug uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccagagcagc accagaggcg gcagcagagu ggagggcauc      900

uucgccggcc uguucaugaa cgccuacggc gccggccagg ugaugcugag auggggcgug      960

cuggccaaga gcgugaagaa caucaugcug ggccacgcca gcgugcaggc cgagauggag     1020

cagguggugg agguguacga guacgcccag aagcugggcg gcgaggccgg cuucuaccac     1080

auccugaaca accccaaggc cagccugcug agccugaccc aguuccccca cuucagcagc     1140

guggugcugg gcaacgccgc cggccugggc aucaugggcg aguacagagg cacccccaga     1200

aaccaggacc uguacgacgc cgccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuaca gcgugcugga ccugaccgcc gaggagcugg aggccaucaa gcaccagcug     1320

aaccccaagg acaacgacgu ggagcuguga ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10468
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10468
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccug aauaaggauc agcuucuguc cucuagcaaa      240

uacacaaucc aaagauccac gggcgacucu auugauaccc ccaacuauga cguccagaag      300

cacaucaaua aacucugcgg gaugcugcuu auuacagagg augcuaacca uaaguucacc      360

ggacugaucg gcaugcucua cgccaugagc cggcuggggc gcgaagacac aauuaagauc      420

cugagagaug cgggauauca cguuaaagcu aauggcgugg acgugaccac acaucggcag      480

gauaucaacg ggaaggagau gaaauuugaa guccucaccc uggccucccu uacgaccgag      540

auucagauca auauugaaau cgagucucgc aagagcuaca aaaagaugcu gaaggagaug      600

ggagaagugg ccccugagua uagacacgac uccccggauu guggcaugau uauccucugc      660

auugcugccc ugguuaucac aaaacuugcu gccggcgacc ggagcgggcu gaccgcggug      720

auccgcagag ccaacaaugu ccucaagaac gaaaugaaac gguacaaggg acugcugccc      780

aaagauauug cuaauucuuu cuaugaggug uuugagaagc auccucacuu caucgacguu      840

uuugugcacu ucggcauugc ccaauccagc acacgcgggg gaucuagagu cgaaggcauc      900

uuugcuggac ucuucaugaa cgccuacggg gcgggccagg ugaugcugcg guggggcgug      960

cuugccaaau ccgucaagaa uauuaugcug gggcaugcua gcguucaggc cgagauggaa     1020

cagguggugg aggucuacga auaugcucaa aagcucggag gcgaggccgg guuuuaccac     1080

auccugaaca aucccaaagc cucucuucug ucccucaccc aguucccuca uuuuagcucc     1140

gugguucugg gaaacgcugc gggccugggg aucaugggag aguaucgcgg cacgcccaga     1200

aaccaggacc ucuacgaugc cgcuaaggcc uaugccgaac agcugaaaga gaauggcgug     1260

auuaacuacu cuguccuuga ccugacagcu gaggaacucg aagccaucaa gcaccaacug     1320

aauccuaaag auaacgacgu ggagcuuuga ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10469
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10469
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cuaagcaaag ucaaauuaaa cgacacauua aacaaagacc aacucuuauc aucaucaaaa      240

uacacaauac aaagaagcac cggagacagu aucgacacac caaacuauga cguccaaaaa      300

cauauaaaua aauuaugcgg caugcucuua aucacagaag acgccaacca uaaauuuaca      360

ggauuaauag gaauguuaua ugcaauguca cgacuaggua gagaagacac aauaaaaaua      420

cuaagagacg caggcuauca cguaaaagca aauggaguag acguaaccac acacagacaa      480

gacauaaaug gaaaagaaau gaaauuugaa guauuaacac uagcaucacu aacaacagaa      540

auacaaauca acauagaaau agaaucaaga aaaagcuaca aaaaaauguu aaaagaaaug      600

ggagaagucg caccagaaua uagacaugau ucaccagacu gcggaaugau aauacuaugc      660

auagcagccc uaguaauuac aaaacuagca gcaggagaca gaagcggauu aacagcagua      720

auaagaagag caaacaacgu acuaaaaaac gaaaugaaaa gauauaaagg auuauuacca      780

aaagacauag caaacucauu cuaugaagua uucgaaaaac acccccacuu uauagacguc      840

uucguacacu ucggaauagc ccaaucaucc acaagaggag gaucaagagu cgaaggaaua      900

uucgcaggau uauucaugaa cgcauauggc gcaggacaag uaaugcuaag auggggagua      960

cuagcaaaau ccgucaaaaa cauaaugcua ggacacgcau caguucaagc agaaauggaa     1020

caaguaguag aaguauacga auacgcccaa aaacuaggag gagaagcagg auucuaccac     1080

auacuaaaua auccaaaagc aucacuacua agccuaaccc aauuucccca cuucucaagu     1140

guaguauuag gaaaugcagc uggacuagga auaaugggag aauacagagg aacaccaaga     1200

aaccaagacu uauacgacgc agcaaaagca uacgcagagc aacuuaaaga aaacggagua     1260

auaaacuaua gcguacuaga cuuaacagca gaagaacugg aagcaauaaa acaucaauua     1320

aacccgaaag acaaugacgu agaauuauaa ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10470
<211>  1629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10470
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cucucgaaag uaaaacucaa cgacacccuc aacaaagacc aacuccuuuc cagcuccaaa      240

uacaccaucc aacgauccac cggagacucc aucgacacgc ccaacuacga cguccagaaa      300

cacaucaaca agcucugcgg aaugcuacua aucaccgagg acgccaacca caaauucaca      360

ggacuuauag ggaugcucua cgccaugucc cgccucggac gcgaagacac aauaaaaauc      420

cuacgagacg ccggcuacca cguaaaggca aacggcgucg acgucaccac acacagacaa      480

gacaucaacg gaaaggaaau gaaauucgaa guccucaccc ucgccagccu aaccaccgag      540

auccaaauca acaucgaaau cgaaucacgc aaauccuaca agaaaaugcu caaagaaaug      600

ggagaagucg cccccgaaua ccgucacgac ucgcccgacu gcggcaugau aauccuaugc      660

aucgccgcac ucgucauaac caaacucgcc gccggugacc gaucaggacu gacagcaguc      720

auccgccgag caaacaacgu gcucaaaaac gaaaugaaac gcuacaaagg ccuacucccc      780

aaagacaucg ccaacuccuu cuacgaaguc uucgaaaaac acccacacuu caucgacguc      840

uucguccacu ucggcaucgc acaaucauca accagaggcg gcagccgcgu ugaaggcauc      900

uucgcaggac ucuuuaugaa cgccuacggc gccggccaag ucaugcuccg cuggggcguc      960

cuggcaaaaa gcgucaaaaa caucaugcua ggccacgcua gcguccaagc cgaaauggaa     1020

caagucgucg aaguuuacga guacgcacaa aaacucggcg gcgaagcagg cuucuaccac     1080

auccuaaaca accccaaagc cucccugcua ucacucaccc aauuccccca cuucuccagc     1140

gucguccucg gcaacgccgc aggacuaggc aucaugggag aauaccgcgg gacaccgcgc     1200

aaccaagacc ucuacgacgc cgccaaagcc uacgccgaac aacucaaaga aaacggcguc     1260

auaaacuacu caguccucga ccucaccgcc gaagaacucg aagccaucaa acaccaacuc     1320

aacccaaaag acaacgacgu cgaauuauaa ggacuaguac uggcugcauc ucccuuuccu     1380

cuguccucca uccuucuccc aggaugguga agggggaccu gguacccagu gauccccacc     1440

ccaggauccu aaaucaugac uuaccugcua auaaaaacuc auuggaaaag ugagaagauc     1500

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1620

accagaauu                                                             1629


<210>  10471
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10471
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcu      180

cuuagcaaag ucaaguugaa ugauacacuc aacaaagauc aacuucuguc auccagcaaa      240

uacaccaucc aacggagcac aggagauagu auugauacuc cuaauuauga ugugcagaaa      300

cacaucaaua aguuaugugg cauguuauua aucacagaag augcuaauca uaaauucacu      360

ggguuaauag guauguuaua ugcgaugucu agguuaggaa gagaagacac cauaaaaaua      420

cucagagaug cgggauauca uguaaaagca aauggaguag auguaacaac acaucgucaa      480

gacauuaaug gaaaagaaau gaaauuugaa guguuaacau uggcaagcuu aacaacugaa      540

auucaaauca acauugagau agaaucuaga aaauccuaca aaaaaaugcu aaaagaaaug      600

ggagagguag cuccagaaua caggcaugac ucuccugauu gugggaugau aauauuaugu      660

auagcagcau uaguaauaac uaaauuagca gcaggggaca gaucuggucu uacagccgug      720

auuaggagag cuaauaaugu ccuaaaaaau gaaaugaaac guuacaaagg cuuacuaccc      780

aaggacauag ccaacagcuu cuaugaagug uuugaaaaac auccccacuu uauagauguu      840

uuuguucauu uugguauagc acaaucuucu accagaggug gcaguagagu ugaagggauu      900

uuugcaggau uguuuaugaa ugccuauggu gcagggcaag ugauguuacg guggggaguc      960

uuagcaaaau caguuaaaaa uauuauguua ggacaugcua gugugcaagc agaaauggaa     1020

caaguuguug agguuuauga auaugcccaa aaauugggug gugaagcagg auucuaccau     1080

auauugaaca acccaaaagc aucauuauua ucuuugacuc aauuuccuca cuucuccagu     1140

guaguauuag gcaaugcugc uggccuaggc auaaugggag aguacagagg uacaccgagg     1200

aaucaagauc uauaugaugc agcaaaggca uaugcugaac aacucaaaga aaauggugug     1260

auuaacuaca guguacuaga cuugacagca gaagaacuag aggcuaucaa acaucagcuu     1320

aauccaaaag auaaugaugu agagcuuuga ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10472
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10472
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcucaa cgacacccug aacaaggacc agcugcucuc cagcuccaag      240

uacaccaucc agcgcagcac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcugugcgg gaugcugcuc aucaccgagg acgccaacca caaguucacc      360

ggccugaucg ggaugcugua cgcgaugagc cggcucggcc gcgaggacac gaucaagauc      420

cugcgggacg ccggguacca cgugaaggcc aacggcgugg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc ucgccucccu gacgaccgag      540

auccagauca acaucgagau cgagagccgg aaguccuaca agaagaugcu gaaggagaug      600

ggggaggugg ccccggagua ccgccacgac agccccgacu gcggcaugau cauccucugc      660

aucgcggccc uggucaucac caagcuggcc gccggggacc gguccggccu caccgcggug      720

auccgccggg ccaacaacgu gcugaagaac gagaugaagc gcuacaaggg gcugcucccc      780

aaggacaucg ccaacagcuu cuacgagguc uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccaguccagc acgcggggcg ggucccgcgu cgagggcauc      900

uucgccgggc uguucaugaa cgcguacggc gccggccagg ugaugcugcg guggggcgug      960

cucgccaaga gcgucaagaa caucaugcug gggcacgccu ccgugcaggc cgagauggag     1020

caggucgugg agguguacga guacgcgcag aagcucgggg gcgaggccgg guucuaccac     1080

auccugaaca acccgaaggc cagccugcug ucccucaccc aguuccccca cuucagcagc     1140

gugguccugg gcaacgccgc cggccugggg aucaugggcg aguaccgcgg gacgccccgg     1200

aaccaggacc ucuacgacgc ggccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuacu ccgugcugga ccucaccgcc gaggagcugg aggcgaucaa gcaccagcug     1320

aaccccaagg acaacgacgu cgagcucuga ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10473
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10473
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cucuccaagg ucaagcucaa cgacacccuc aacaaggacc agcuccucuc cuccuccaag      240

uacaccaucc agcgcuccac cggcgacucc aucgacaccc ccaacuacga cguccagaag      300

cacaucaaca agcucugcgg caugcuccuc aucaccgagg acgccaacca caaguucacc      360

ggccucaucg gcaugcucua cgccaugucc cgccucggcc gcgaggacac caucaagauc      420

cuccgcgacg ccggcuacca cgucaaggcc aacggcgucg acgucaccac ccaccgccag      480

gacaucaacg gcaaggagau gaaguucgag guccucaccc ucgccucccu caccaccgag      540

auccagauca acaucgagau cgagucccgc aaguccuaca agaagaugcu caaggagaug      600

ggcgaggucg cccccgagua ccgccacgac ucccccgacu gcggcaugau cauccucugc      660

aucgccgccc ucgucaucac caagcucgcc gccggcgacc gcuccggccu caccgccguc      720

auccgccgcg ccaacaacgu ccucaagaac gagaugaagc gcuacaaggg ccuccucccc      780

aaggacaucg ccaacuccuu cuacgagguc uucgagaagc acccccacuu caucgacguc      840

uucguccacu ucggcaucgc ccaguccucc acccgcggcg gcucccgcgu cgagggcauc      900

uucgccggcc ucuucaugaa cgccuacggc gccggccagg ucaugcuccg cuggggcguc      960

cucgccaagu ccgucaagaa caucaugcuc ggccacgccu ccguccaggc cgagauggag     1020

caggucgucg aggucuacga guacgcccag aagcucggcg gcgaggccgg cuucuaccac     1080

auccucaaca accccaaggc cucccuccuc ucccucaccc aguuccccca cuucuccucc     1140

gucguccucg gcaacgccgc cggccucggc aucaugggcg aguaccgcgg caccccccgc     1200

aaccaggacc ucuacgacgc cgccaaggcc uacgccgagc agcucaagga gaacggcguc     1260

aucaacuacu ccguccucga ccucaccgcc gaggagcucg aggccaucaa gcaccagcuc     1320

aaccccaagg acaacgacgu cgagcucuga ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10474
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10474
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccuu aauaaggauc agcuguuguc cucuucaaaa      240

uacacaaucc aaagaaguac uggcgacagc auugauacgc ccaacuauga cguccagaag      300

cacauaaaua aauuaugcgg gaugcugcua aucaccgagg augcuaacca uaaguucaca      360

ggacucauug guaugcugua cgcaaugucc aggcuuggcc gggaagacac uaucaagauu      420

cugcgcgaug ccggguauca cguuaaagcg aauggagugg acguaaccac acaucgacag      480

gauaucaacg gcaaggagau gaaauuugaa guguugaccc ucgcuucucu gacuacagag      540

auacagauca auauugaaau cgagucgcgu aagucauaca aaaagaugcu gaaggagaug      600

ggugaagucg ccccugagua uagacacgac agcccagauu gugggaugau uauccucugc      660

auagcagccu uagugauuac caaacuggcu gcaggagaca ggaguggccu uacggccguu      720

auccggcgcg cuaacaaugu guugaagaac gaaaugaaaa gauacaaggg ccugcuaccg      780

aaagauauug ccaauuccuu cuaugagguc uuugagaagc auccccacuu caucgacgug      840

uuuguacacu ucgggaucgc gcaaucuagc acuaggggag guucccgggu ugaaggcauu      900

uuugcaggac ucuucaugaa cgccuacggg gcuggccagg ugaugcugcg cugggguguc      960

cuugccaaau cagugaagaa uauaaugcug gggcaugcaa gugugcaggc ugagauggaa     1020

caggucguug agguguacga auaugcccaa aaguugggag gcgaggcggg cuuuuaccac     1080

auccucaaca auccuaaagc cagccuguua ucucugaccc aguucccaca uuuuuccuca     1140

guagugcucg ggaacgcagc uggacuuggu auuaugggcg aguaucgagg gacacccaga     1200

aaccaggacc uguacgaugc cgcuaaggcc uaugcagaac aguugaaaga gaauggaguc     1260

aucaacuaca gcgugcuaga ccugacugcc gaggaacucg aagcuauaaa gcaccaacug     1320

aauccuaaag auaacgacgu ugagcuuuga ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10475
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10475
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaagcugaa cgacacccug aacaaggacc agcugcugag cagcagcaag      240

uacaccaucc agagaagcac cggcgacagc aucgacaccc ccaacuacga cgugcagaag      300

cacaucaaca agcugugcgg caugcugcug aucaccgagg acgccaacca caaguucacc      360

ggccugaucg gcaugcugua cgccaugagc agacugggca gagaggacac caucaagauc      420

cugagagacg ccggcuacca cgugaaggcc aacggcgugg acgugaccac ccacagacag      480

gacaucaacg gcaaggagau gaaguucgag gugcugaccc uggccagccu gaccaccgag      540

auccagauca acaucgagau cgagagcaga aagagcuaca agaagaugcu gaaggagaug      600

ggcgaggugg cccccgagua cagacacgac agccccgacu gcggcaugau cauccugugc      660

aucgccgccc uggugaucac caagcuggcc gccggcgaca gaagcggccu gaccgccgug      720

aucagaagag ccaacaacgu gcugaagaac gagaugaaga gauacaaggg ccugcugccc      780

aaggacaucg ccaacagcuu cuacgaggug uucgagaagc acccccacuu caucgacgug      840

uucgugcacu ucggcaucgc ccagagcagc accagaggcg gcagcagagu ggagggcauc      900

uucgccggcc uguucaugaa cgccuacggc gccggccagg ugaugcugag auggggcgug      960

cuggccaaga gcgugaagaa caucaugcug ggccacgcca gcgugcaggc cgagauggag     1020

cagguggugg agguguacga guacgcccag aagcugggcg gcgaggccgg cuucuaccac     1080

auccugaaca accccaaggc cagccugcug agccugaccc aguuccccca cuucagcagc     1140

guggugcugg gcaacgccgc cggccugggc aucaugggcg aguacagagg cacccccaga     1200

aaccaggacc uguacgacgc cgccaaggcc uacgccgagc agcugaagga gaacggcgug     1260

aucaacuaca gcgugcugga ccugaccgcc gaggagcugg aggccaucaa gcaccagcug     1320

aaccccaagg acaacgacgu ggagcuguga ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10476
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10476
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggcc      180

cugagcaagg ugaaacucaa cgacacccug aauaaggauc agcuucuguc cucuagcaaa      240

uacacaaucc aaagauccac gggcgacucu auugauaccc ccaacuauga cguccagaag      300

cacaucaaua aacucugcgg gaugcugcuu auuacagagg augcuaacca uaaguucacc      360

ggacugaucg gcaugcucua cgccaugagc cggcuggggc gcgaagacac aauuaagauc      420

cugagagaug cgggauauca cguuaaagcu aauggcgugg acgugaccac acaucggcag      480

gauaucaacg ggaaggagau gaaauuugaa guccucaccc uggccucccu uacgaccgag      540

auucagauca auauugaaau cgagucucgc aagagcuaca aaaagaugcu gaaggagaug      600

ggagaagugg ccccugagua uagacacgac uccccggauu guggcaugau uauccucugc      660

auugcugccc ugguuaucac aaaacuugcu gccggcgacc ggagcgggcu gaccgcggug      720

auccgcagag ccaacaaugu ccucaagaac gaaaugaaac gguacaaggg acugcugccc      780

aaagauauug cuaauucuuu cuaugaggug uuugagaagc auccucacuu caucgacguu      840

uuugugcacu ucggcauugc ccaauccagc acacgcgggg gaucuagagu cgaaggcauc      900

uuugcuggac ucuucaugaa cgccuacggg gcgggccagg ugaugcugcg guggggcgug      960

cuugccaaau ccgucaagaa uauuaugcug gggcaugcua gcguucaggc cgagauggaa     1020

cagguggugg aggucuacga auaugcucaa aagcucggag gcgaggccgg guuuuaccac     1080

auccugaaca aucccaaagc cucucuucug ucccucaccc aguucccuca uuuuagcucc     1140

gugguucugg gaaacgcugc gggccugggg aucaugggag aguaucgcgg cacgcccaga     1200

aaccaggacc ucuacgaugc cgcuaaggcc uaugccgaac agcugaaaga gaauggcgug     1260

auuaacuacu cuguccuuga ccugacagcu gaggaacucg aagccaucaa gcaccaacug     1320

aauccuaaag auaacgacgu ggagcuuuga ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10477
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10477
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cuaagcaaag ucaaauuaaa cgacacauua aacaaagacc aacucuuauc aucaucaaaa      240

uacacaauac aaagaagcac cggagacagu aucgacacac caaacuauga cguccaaaaa      300

cauauaaaua aauuaugcgg caugcucuua aucacagaag acgccaacca uaaauuuaca      360

ggauuaauag gaauguuaua ugcaauguca cgacuaggua gagaagacac aauaaaaaua      420

cuaagagacg caggcuauca cguaaaagca aauggaguag acguaaccac acacagacaa      480

gacauaaaug gaaaagaaau gaaauuugaa guauuaacac uagcaucacu aacaacagaa      540

auacaaauca acauagaaau agaaucaaga aaaagcuaca aaaaaauguu aaaagaaaug      600

ggagaagucg caccagaaua uagacaugau ucaccagacu gcggaaugau aauacuaugc      660

auagcagccc uaguaauuac aaaacuagca gcaggagaca gaagcggauu aacagcagua      720

auaagaagag caaacaacgu acuaaaaaac gaaaugaaaa gauauaaagg auuauuacca      780

aaagacauag caaacucauu cuaugaagua uucgaaaaac acccccacuu uauagacguc      840

uucguacacu ucggaauagc ccaaucaucc acaagaggag gaucaagagu cgaaggaaua      900

uucgcaggau uauucaugaa cgcauauggc gcaggacaag uaaugcuaag auggggagua      960

cuagcaaaau ccgucaaaaa cauaaugcua ggacacgcau caguucaagc agaaauggaa     1020

caaguaguag aaguauacga auacgcccaa aaacuaggag gagaagcagg auucuaccac     1080

auacuaaaua auccaaaagc aucacuacua agccuaaccc aauuucccca cuucucaagu     1140

guaguauuag gaaaugcagc uggacuagga auaaugggag aauacagagg aacaccaaga     1200

aaccaagacu uauacgacgc agcaaaagca uacgcagagc aacuuaaaga aaacggagua     1260

auaaacuaua gcguacuaga cuuaacagca gaagaacugg aagcaauaaa acaucaauua     1320

aacccgaaag acaaugacgu agaauuauaa ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10478
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10478
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggca      180

cucucgaaag uaaaacucaa cgacacccuc aacaaagacc aacuccuuuc cagcuccaaa      240

uacaccaucc aacgauccac cggagacucc aucgacacgc ccaacuacga cguccagaaa      300

cacaucaaca agcucugcgg aaugcuacua aucaccgagg acgccaacca caaauucaca      360

ggacuuauag ggaugcucua cgccaugucc cgccucggac gcgaagacac aauaaaaauc      420

cuacgagacg ccggcuacca cguaaaggca aacggcgucg acgucaccac acacagacaa      480

gacaucaacg gaaaggaaau gaaauucgaa guccucaccc ucgccagccu aaccaccgag      540

auccaaauca acaucgaaau cgaaucacgc aaauccuaca agaaaaugcu caaagaaaug      600

ggagaagucg cccccgaaua ccgucacgac ucgcccgacu gcggcaugau aauccuaugc      660

aucgccgcac ucgucauaac caaacucgcc gccggugacc gaucaggacu gacagcaguc      720

auccgccgag caaacaacgu gcucaaaaac gaaaugaaac gcuacaaagg ccuacucccc      780

aaagacaucg ccaacuccuu cuacgaaguc uucgaaaaac acccacacuu caucgacguc      840

uucguccacu ucggcaucgc acaaucauca accagaggcg gcagccgcgu ugaaggcauc      900

uucgcaggac ucuuuaugaa cgccuacggc gccggccaag ucaugcuccg cuggggcguc      960

cuggcaaaaa gcgucaaaaa caucaugcua ggccacgcua gcguccaagc cgaaauggaa     1020

caagucgucg aaguuuacga guacgcacaa aaacucggcg gcgaagcagg cuucuaccac     1080

auccuaaaca accccaaagc cucccugcua ucacucaccc aauuccccca cuucuccagc     1140

gucguccucg gcaacgccgc aggacuaggc aucaugggag aauaccgcgg gacaccgcgc     1200

aaccaagacc ucuacgacgc cgccaaagcc uacgccgaac aacucaaaga aaacggcguc     1260

auaaacuacu caguccucga ccucaccgcc gaagaacucg aagccaucaa acaccaacuc     1320

aacccaaaag acaacgacgu cgaauuauaa ggacuagugu ccaccugucc cuccugggcu     1380

gcuggauugu cucguuuucc ugccaaauaa acaggaucag cgcuuuacag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10479
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10479
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcucuuagca aagucaaguu gaaugauaca cucaacaaag aucaacuucu gucauccagc      120

aaauacacca uccaacggag cacaggagau aguauugaua cuccuaauua ugaugugcag      180

aaacacauca auaaguuaug uggcauguua uuaaucacag aagaugcuaa ucauaaauuc      240

acuggguuaa uagguauguu auaugcgaug ucuagguuag gaagagaaga caccauaaaa      300

auacucagag augcgggaua ucauguaaaa gcaaauggag uagauguaac aacacaucgu      360

caagacauua auggaaaaga aaugaaauuu gaaguguuaa cauuggcaag cuuaacaacu      420

gaaauucaaa ucaacauuga gauagaaucu agaaaauccu acaaaaaaau gcuaaaagaa      480

augggagagg uagcuccaga auacaggcau gacucuccug auugugggau gauaauauua      540

uguauagcag cauuaguaau aacuaaauua gcagcagggg acagaucugg ucuuacagcc      600

gugauuagga gagcuaauaa uguccuaaaa aaugaaauga aacguuacaa aggcuuacua      660

cccaaggaca uagccaacag cuucuaugaa guguuugaaa aacaucccca cuuuauagau      720

guuuuuguuc auuuugguau agcacaaucu ucuaccagag guggcaguag aguugaaggg      780

auuuuugcag gauuguuuau gaaugccuau ggugcagggc aagugauguu acggugggga      840

gucuuagcaa aaucaguuaa aaauauuaug uuaggacaug cuagugugca agcagaaaug      900

gaacaaguug uugagguuua ugaauaugcc caaaaauugg guggugaagc aggauucuac      960

cauauauuga acaacccaaa agcaucauua uuaucuuuga cucaauuucc ucacuucucc     1020

aguguaguau uaggcaaugc ugcuggccua ggcauaaugg gagaguacag agguacaccg     1080

aggaaucaag aucuauauga ugcagcaaag gcauaugcug aacaacucaa agaaaauggu     1140

gugauuaacu acaguguacu agacuugaca gcagaagaac uagaggcuau caaacaucag     1200

cuuaauccaa aagauaauga uguagagcuu ugaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10480
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10480
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcccugagca aggugaagcu caacgacacc cugaacaagg accagcugcu cuccagcucc      120

aaguacacca uccagcgcag caccggcgac uccaucgaca cccccaacua cgacguccag      180

aagcacauca acaagcugug cgggaugcug cucaucaccg aggacgccaa ccacaaguuc      240

accggccuga ucgggaugcu guacgcgaug agccggcucg gccgcgagga cacgaucaag      300

auccugcggg acgccgggua ccacgugaag gccaacggcg uggacgucac cacccaccgc      360

caggacauca acggcaagga gaugaaguuc gaggugcuga cccucgccuc ccugacgacc      420

gagauccaga ucaacaucga gaucgagagc cggaaguccu acaagaagau gcugaaggag      480

augggggagg uggccccgga guaccgccac gacagccccg acugcggcau gaucauccuc      540

ugcaucgcgg cccuggucau caccaagcug gccgccgggg accgguccgg ccucaccgcg      600

gugauccgcc gggccaacaa cgugcugaag aacgagauga agcgcuacaa ggggcugcuc      660

cccaaggaca ucgccaacag cuucuacgag gucuucgaga agcaccccca cuucaucgac      720

guguucgugc acuucggcau cgcccagucc agcacgcggg gcgggucccg cgucgagggc      780

aucuucgccg ggcuguucau gaacgcguac ggcgccggcc aggugaugcu gcgguggggc      840

gugcucgcca agagcgucaa gaacaucaug cuggggcacg ccuccgugca ggccgagaug      900

gagcaggucg uggaggugua cgaguacgcg cagaagcucg ggggcgaggc cggguucuac      960

cacauccuga acaacccgaa ggccagccug cugucccuca cccaguuccc ccacuucagc     1020

agcguggucc ugggcaacgc cgccggccug gggaucaugg gcgaguaccg cgggacgccc     1080

cggaaccagg accucuacga cgcggccaag gccuacgccg agcagcugaa ggagaacggc     1140

gugaucaacu acuccgugcu ggaccucacc gccgaggagc uggaggcgau caagcaccag     1200

cugaacccca aggacaacga cgucgagcuc ugaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10481
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10481
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcccucucca aggucaagcu caacgacacc cucaacaagg accagcuccu cuccuccucc      120

aaguacacca uccagcgcuc caccggcgac uccaucgaca cccccaacua cgacguccag      180

aagcacauca acaagcucug cggcaugcuc cucaucaccg aggacgccaa ccacaaguuc      240

accggccuca ucggcaugcu cuacgccaug ucccgccucg gccgcgagga caccaucaag      300

auccuccgcg acgccggcua ccacgucaag gccaacggcg ucgacgucac cacccaccgc      360

caggacauca acggcaagga gaugaaguuc gagguccuca cccucgccuc ccucaccacc      420

gagauccaga ucaacaucga gaucgagucc cgcaaguccu acaagaagau gcucaaggag      480

augggcgagg ucgcccccga guaccgccac gacucccccg acugcggcau gaucauccuc      540

ugcaucgccg cccucgucau caccaagcuc gccgccggcg accgcuccgg ccucaccgcc      600

gucauccgcc gcgccaacaa cguccucaag aacgagauga agcgcuacaa gggccuccuc      660

cccaaggaca ucgccaacuc cuucuacgag gucuucgaga agcaccccca cuucaucgac      720

gucuucgucc acuucggcau cgcccagucc uccacccgcg gcggcucccg cgucgagggc      780

aucuucgccg gccucuucau gaacgccuac ggcgccggcc aggucaugcu ccgcuggggc      840

guccucgcca aguccgucaa gaacaucaug cucggccacg ccuccgucca ggccgagaug      900

gagcaggucg ucgaggucua cgaguacgcc cagaagcucg gcggcgaggc cggcuucuac      960

cacauccuca acaaccccaa ggccucccuc cucucccuca cccaguuccc ccacuucucc     1020

uccgucgucc ucggcaacgc cgccggccuc ggcaucaugg gcgaguaccg cggcaccccc     1080

cgcaaccagg accucuacga cgccgccaag gccuacgccg agcagcucaa ggagaacggc     1140

gucaucaacu acuccguccu cgaccucacc gccgaggagc ucgaggccau caagcaccag     1200

cucaacccca aggacaacga cgucgagcuc ugaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10482
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10482
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcccugagca aggugaaacu caacgacacc cuuaauaagg aucagcuguu guccucuuca      120

aaauacacaa uccaaagaag uacuggcgac agcauugaua cgcccaacua ugacguccag      180

aagcacauaa auaaauuaug cgggaugcug cuaaucaccg aggaugcuaa ccauaaguuc      240

acaggacuca uugguaugcu guacgcaaug uccaggcuug gccgggaaga cacuaucaag      300

auucugcgcg augccgggua ucacguuaaa gcgaauggag uggacguaac cacacaucga      360

caggauauca acggcaagga gaugaaauuu gaaguguuga cccucgcuuc ucugacuaca      420

gagauacaga ucaauauuga aaucgagucg cguaagucau acaaaaagau gcugaaggag      480

augggugaag ucgccccuga guauagacac gacagcccag auugugggau gauuauccuc      540

ugcauagcag ccuuagugau uaccaaacug gcugcaggag acaggagugg ccuuacggcc      600

guuauccggc gcgcuaacaa uguguugaag aacgaaauga aaagauacaa gggccugcua      660

ccgaaagaua uugccaauuc cuucuaugag gucuuugaga agcaucccca cuucaucgac      720

guguuuguac acuucgggau cgcgcaaucu agcacuaggg gagguucccg gguugaaggc      780

auuuuugcag gacucuucau gaacgccuac ggggcuggcc aggugaugcu gcgcuggggu      840

guccuugcca aaucagugaa gaauauaaug cuggggcaug caagugugca ggcugagaug      900

gaacaggucg uugaggugua cgaauaugcc caaaaguugg gaggcgaggc gggcuuuuac      960

cacauccuca acaauccuaa agccagccug uuaucucuga cccaguuccc acauuuuucc     1020

ucaguagugc ucgggaacgc agcuggacuu gguauuaugg gcgaguaucg agggacaccc     1080

agaaaccagg accuguacga ugccgcuaag gccuaugcag aacaguugaa agagaaugga     1140

gucaucaacu acagcgugcu agaccugacu gccgaggaac ucgaagcuau aaagcaccaa     1200

cugaauccua aagauaacga cguugagcuu ugaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10483
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10483
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcccugagca aggugaagcu gaacgacacc cugaacaagg accagcugcu gagcagcagc      120

aaguacacca uccagagaag caccggcgac agcaucgaca cccccaacua cgacgugcag      180

aagcacauca acaagcugug cggcaugcug cugaucaccg aggacgccaa ccacaaguuc      240

accggccuga ucggcaugcu guacgccaug agcagacugg gcagagagga caccaucaag      300

auccugagag acgccggcua ccacgugaag gccaacggcg uggacgugac cacccacaga      360

caggacauca acggcaagga gaugaaguuc gaggugcuga cccuggccag ccugaccacc      420

gagauccaga ucaacaucga gaucgagagc agaaagagcu acaagaagau gcugaaggag      480

augggcgagg uggcccccga guacagacac gacagccccg acugcggcau gaucauccug      540

ugcaucgccg cccuggugau caccaagcug gccgccggcg acagaagcgg ccugaccgcc      600

gugaucagaa gagccaacaa cgugcugaag aacgagauga agagauacaa gggccugcug      660

cccaaggaca ucgccaacag cuucuacgag guguucgaga agcaccccca cuucaucgac      720

guguucgugc acuucggcau cgcccagagc agcaccagag gcggcagcag aguggagggc      780

aucuucgccg gccuguucau gaacgccuac ggcgccggcc aggugaugcu gagauggggc      840

gugcuggcca agagcgugaa gaacaucaug cugggccacg ccagcgugca ggccgagaug      900

gagcaggugg uggaggugua cgaguacgcc cagaagcugg gcggcgaggc cggcuucuac      960

cacauccuga acaaccccaa ggccagccug cugagccuga cccaguuccc ccacuucagc     1020

agcguggugc ugggcaacgc cgccggccug ggcaucaugg gcgaguacag aggcaccccc     1080

agaaaccagg accuguacga cgccgccaag gccuacgccg agcagcugaa ggagaacggc     1140

gugaucaacu acagcgugcu ggaccugacc gccgaggagc uggaggccau caagcaccag     1200

cugaacccca aggacaacga cguggagcug ugaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10484
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10484
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcccugagca aggugaaacu caacgacacc cugaauaagg aucagcuucu guccucuagc      120

aaauacacaa uccaaagauc cacgggcgac ucuauugaua cccccaacua ugacguccag      180

aagcacauca auaaacucug cgggaugcug cuuauuacag aggaugcuaa ccauaaguuc      240

accggacuga ucggcaugcu cuacgccaug agccggcugg ggcgcgaaga cacaauuaag      300

auccugagag augcgggaua ucacguuaaa gcuaauggcg uggacgugac cacacaucgg      360

caggauauca acgggaagga gaugaaauuu gaaguccuca cccuggccuc ccuuacgacc      420

gagauucaga ucaauauuga aaucgagucu cgcaagagcu acaaaaagau gcugaaggag      480

augggagaag uggccccuga guauagacac gacuccccgg auuguggcau gauuauccuc      540

ugcauugcug cccugguuau cacaaaacuu gcugccggcg accggagcgg gcugaccgcg      600

gugauccgca gagccaacaa uguccucaag aacgaaauga aacgguacaa gggacugcug      660

cccaaagaua uugcuaauuc uuucuaugag guguuugaga agcauccuca cuucaucgac      720

guuuuugugc acuucggcau ugcccaaucc agcacacgcg ggggaucuag agucgaaggc      780

aucuuugcug gacucuucau gaacgccuac ggggcgggcc aggugaugcu gcgguggggc      840

gugcuugcca aauccgucaa gaauauuaug cuggggcaug cuagcguuca ggccgagaug      900

gaacaggugg uggaggucua cgaauaugcu caaaagcucg gaggcgaggc cggguuuuac      960

cacauccuga acaaucccaa agccucucuu cugucccuca cccaguuccc ucauuuuagc     1020

uccgugguuc ugggaaacgc ugcgggccug gggaucaugg gagaguaucg cggcacgccc     1080

agaaaccagg accucuacga ugccgcuaag gccuaugccg aacagcugaa agagaauggc     1140

gugauuaacu acucuguccu ugaccugaca gcugaggaac ucgaagccau caagcaccaa     1200

cugaauccua aagauaacga cguggagcuu ugaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10485
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10485
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcacuaagca aagucaaauu aaacgacaca uuaaacaaag accaacucuu aucaucauca      120

aaauacacaa uacaaagaag caccggagac aguaucgaca caccaaacua ugacguccaa      180

aaacauauaa auaaauuaug cggcaugcuc uuaaucacag aagacgccaa ccauaaauuu      240

acaggauuaa uaggaauguu auaugcaaug ucacgacuag guagagaaga cacaauaaaa      300

auacuaagag acgcaggcua ucacguaaaa gcaaauggag uagacguaac cacacacaga      360

caagacauaa auggaaaaga aaugaaauuu gaaguauuaa cacuagcauc acuaacaaca      420

gaaauacaaa ucaacauaga aauagaauca agaaaaagcu acaaaaaaau guuaaaagaa      480

augggagaag ucgcaccaga auauagacau gauucaccag acugcggaau gauaauacua      540

ugcauagcag cccuaguaau uacaaaacua gcagcaggag acagaagcgg auuaacagca      600

guaauaagaa gagcaaacaa cguacuaaaa aacgaaauga aaagauauaa aggauuauua      660

ccaaaagaca uagcaaacuc auucuaugaa guauucgaaa aacaccccca cuuuauagac      720

gucuucguac acuucggaau agcccaauca uccacaagag gaggaucaag agucgaagga      780

auauucgcag gauuauucau gaacgcauau ggcgcaggac aaguaaugcu aagaugggga      840

guacuagcaa aauccgucaa aaacauaaug cuaggacacg caucaguuca agcagaaaug      900

gaacaaguag uagaaguaua cgaauacgcc caaaaacuag gaggagaagc aggauucuac      960

cacauacuaa auaauccaaa agcaucacua cuaagccuaa cccaauuucc ccacuucuca     1020

aguguaguau uaggaaaugc agcuggacua ggaauaaugg gagaauacag aggaacacca     1080

agaaaccaag acuuauacga cgcagcaaaa gcauacgcag agcaacuuaa agaaaacgga     1140

guaauaaacu auagcguacu agacuuaaca gcagaagaac uggaagcaau aaaacaucaa     1200

uuaaacccga aagacaauga cguagaauua uaaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10486
<211>  1562
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10486
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gcacucucga aaguaaaacu caacgacacc cucaacaaag accaacuccu uuccagcucc      120

aaauacacca uccaacgauc caccggagac uccaucgaca cgcccaacua cgacguccag      180

aaacacauca acaagcucug cggaaugcua cuaaucaccg aggacgccaa ccacaaauuc      240

acaggacuua uagggaugcu cuacgccaug ucccgccucg gacgcgaaga cacaauaaaa      300

auccuacgag acgccggcua ccacguaaag gcaaacggcg ucgacgucac cacacacaga      360

caagacauca acggaaagga aaugaaauuc gaaguccuca cccucgccag ccuaaccacc      420

gagauccaaa ucaacaucga aaucgaauca cgcaaauccu acaagaaaau gcucaaagaa      480

augggagaag ucgcccccga auaccgucac gacucgcccg acugcggcau gauaauccua      540

ugcaucgccg cacucgucau aaccaaacuc gccgccggug accgaucagg acugacagca      600

gucauccgcc gagcaaacaa cgugcucaaa aacgaaauga aacgcuacaa aggccuacuc      660

cccaaagaca ucgccaacuc cuucuacgaa gucuucgaaa aacacccaca cuucaucgac      720

gucuucgucc acuucggcau cgcacaauca ucaaccagag gcggcagccg cguugaaggc      780

aucuucgcag gacucuuuau gaacgccuac ggcgccggcc aagucaugcu ccgcuggggc      840

guccuggcaa aaagcgucaa aaacaucaug cuaggccacg cuagcgucca agccgaaaug      900

gaacaagucg ucgaaguuua cgaguacgca caaaaacucg gcggcgaagc aggcuucuac      960

cacauccuaa acaaccccaa agccucccug cuaucacuca cccaauuccc ccacuucucc     1020

agcgucgucc ucggcaacgc cgcaggacua ggcaucaugg gagaauaccg cgggacaccg     1080

cgcaaccaag accucuacga cgccgccaaa gccuacgccg aacaacucaa agaaaacggc     1140

gucauaaacu acucaguccu cgaccucacc gccgaagaac ucgaagccau caaacaccaa     1200

cucaacccaa aagacaacga cgucgaauua uaaggacuag ugcaucacau uuaaaagcau     1260

cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu     1320

uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau     1380

uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1500

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1560

uu                                                                    1562


<210>  10487
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10487
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcuc       60

uuagcaaagu caaguugaau gauacacuca acaaagauca acuucuguca uccagcaaau      120

acaccaucca acggagcaca ggagauagua uugauacucc uaauuaugau gugcagaaac      180

acaucaauaa guuauguggc auguuauuaa ucacagaaga ugcuaaucau aaauucacug      240

gguuaauagg uauguuauau gcgaugucua gguuaggaag agaagacacc auaaaaauac      300

ucagagaugc gggauaucau guaaaagcaa auggaguaga uguaacaaca caucgucaag      360

acauuaaugg aaaagaaaug aaauuugaag uguuaacauu ggcaagcuua acaacugaaa      420

uucaaaucaa cauugagaua gaaucuagaa aauccuacaa aaaaaugcua aaagaaaugg      480

gagagguagc uccagaauac aggcaugacu cuccugauug ugggaugaua auauuaugua      540

uagcagcauu aguaauaacu aaauuagcag caggggacag aucuggucuu acagccguga      600

uuaggagagc uaauaauguc cuaaaaaaug aaaugaaacg uuacaaaggc uuacuaccca      660

aggacauagc caacagcuuc uaugaagugu uugaaaaaca uccccacuuu auagauguuu      720

uuguucauuu ugguauagca caaucuucua ccagaggugg caguagaguu gaagggauuu      780

uugcaggauu guuuaugaau gccuauggug cagggcaagu gauguuacgg uggggagucu      840

uagcaaaauc aguuaaaaau auuauguuag gacaugcuag ugugcaagca gaaauggaac      900

aaguuguuga gguuuaugaa uaugcccaaa aauugggugg ugaagcagga uucuaccaua      960

uauugaacaa cccaaaagca ucauuauuau cuuugacuca auuuccucac uucuccagug     1020

uaguauuagg caaugcugcu ggccuaggca uaaugggaga guacagaggu acaccgagga     1080

aucaagaucu auaugaugca gcaaaggcau augcugaaca acucaaagaa aaugguguga     1140

uuaacuacag uguacuagac uugacagcag aagaacuaga ggcuaucaaa caucagcuua     1200

auccaaaaga uaaugaugua gagcuuugag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10488
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1)

<400>  10488
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagcaaggu gaagcucaac gacacccuga acaaggacca gcugcucucc agcuccaagu      120

acaccaucca gcgcagcacc ggcgacucca ucgacacccc caacuacgac guccagaagc      180

acaucaacaa gcugugcggg augcugcuca ucaccgagga cgccaaccac aaguucaccg      240

gccugaucgg gaugcuguac gcgaugagcc ggcucggccg cgaggacacg aucaagaucc      300

ugcgggacgc cggguaccac gugaaggcca acggcgugga cgucaccacc caccgccagg      360

acaucaacgg caaggagaug aaguucgagg ugcugacccu cgccucccug acgaccgaga      420

uccagaucaa caucgagauc gagagccgga aguccuacaa gaagaugcug aaggagaugg      480

gggagguggc cccggaguac cgccacgaca gccccgacug cggcaugauc auccucugca      540

ucgcggcccu ggucaucacc aagcuggccg ccggggaccg guccggccuc accgcgguga      600

uccgccgggc caacaacgug cugaagaacg agaugaagcg cuacaagggg cugcucccca      660

aggacaucgc caacagcuuc uacgaggucu ucgagaagca cccccacuuc aucgacgugu      720

ucgugcacuu cggcaucgcc caguccagca cgcggggcgg gucccgcguc gagggcaucu      780

ucgccgggcu guucaugaac gcguacggcg ccggccaggu gaugcugcgg uggggcgugc      840

ucgccaagag cgucaagaac aucaugcugg ggcacgccuc cgugcaggcc gagauggagc      900

aggucgugga gguguacgag uacgcgcaga agcucggggg cgaggccggg uucuaccaca      960

uccugaacaa cccgaaggcc agccugcugu cccucaccca guucccccac uucagcagcg     1020

ugguccuggg caacgccgcc ggccugggga ucaugggcga guaccgcggg acgccccgga     1080

accaggaccu cuacgacgcg gccaaggccu acgccgagca gcugaaggag aacggcguga     1140

ucaacuacuc cgugcuggac cucaccgccg aggagcugga ggcgaucaag caccagcuga     1200

accccaagga caacgacguc gagcucugag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10489
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10489
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ucuccaaggu caagcucaac gacacccuca acaaggacca gcuccucucc uccuccaagu      120

acaccaucca gcgcuccacc ggcgacucca ucgacacccc caacuacgac guccagaagc      180

acaucaacaa gcucugcggc augcuccuca ucaccgagga cgccaaccac aaguucaccg      240

gccucaucgg caugcucuac gccauguccc gccucggccg cgaggacacc aucaagaucc      300

uccgcgacgc cggcuaccac gucaaggcca acggcgucga cgucaccacc caccgccagg      360

acaucaacgg caaggagaug aaguucgagg uccucacccu cgccucccuc accaccgaga      420

uccagaucaa caucgagauc gagucccgca aguccuacaa gaagaugcuc aaggagaugg      480

gcgaggucgc ccccgaguac cgccacgacu cccccgacug cggcaugauc auccucugca      540

ucgccgcccu cgucaucacc aagcucgccg ccggcgaccg cuccggccuc accgccguca      600

uccgccgcgc caacaacguc cucaagaacg agaugaagcg cuacaagggc cuccucccca      660

aggacaucgc caacuccuuc uacgaggucu ucgagaagca cccccacuuc aucgacgucu      720

ucguccacuu cggcaucgcc caguccucca cccgcggcgg cucccgcguc gagggcaucu      780

ucgccggccu cuucaugaac gccuacggcg ccggccaggu caugcuccgc uggggcgucc      840

ucgccaaguc cgucaagaac aucaugcucg gccacgccuc cguccaggcc gagauggagc      900

aggucgucga ggucuacgag uacgcccaga agcucggcgg cgaggccggc uucuaccaca      960

uccucaacaa ccccaaggcc ucccuccucu cccucaccca guucccccac uucuccuccg     1020

ucguccucgg caacgccgcc ggccucggca ucaugggcga guaccgcggc accccccgca     1080

accaggaccu cuacgacgcc gccaaggccu acgccgagca gcucaaggag aacggcguca     1140

ucaacuacuc cguccucgac cucaccgccg aggagcucga ggccaucaag caccagcuca     1200

accccaagga caacgacguc gagcucugag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10490
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10490
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagcaaggu gaaacucaac gacacccuua auaaggauca gcuguugucc ucuucaaaau      120

acacaaucca aagaaguacu ggcgacagca uugauacgcc caacuaugac guccagaagc      180

acauaaauaa auuaugcggg augcugcuaa ucaccgagga ugcuaaccau aaguucacag      240

gacucauugg uaugcuguac gcaaugucca ggcuuggccg ggaagacacu aucaagauuc      300

ugcgcgaugc cggguaucac guuaaagcga auggagugga cguaaccaca caucgacagg      360

auaucaacgg caaggagaug aaauuugaag uguugacccu cgcuucucug acuacagaga      420

uacagaucaa uauugaaauc gagucgcgua agucauacaa aaagaugcug aaggagaugg      480

gugaagucgc cccugaguau agacacgaca gcccagauug ugggaugauu auccucugca      540

uagcagccuu agugauuacc aaacuggcug caggagacag gaguggccuu acggccguua      600

uccggcgcgc uaacaaugug uugaagaacg aaaugaaaag auacaagggc cugcuaccga      660

aagauauugc caauuccuuc uaugaggucu uugagaagca uccccacuuc aucgacgugu      720

uuguacacuu cgggaucgcg caaucuagca cuaggggagg uucccggguu gaaggcauuu      780

uugcaggacu cuucaugaac gccuacgggg cuggccaggu gaugcugcgc uggggugucc      840

uugccaaauc agugaagaau auaaugcugg ggcaugcaag ugugcaggcu gagauggaac      900

aggucguuga gguguacgaa uaugcccaaa aguugggagg cgaggcgggc uuuuaccaca      960

uccucaacaa uccuaaagcc agccuguuau cucugaccca guucccacau uuuuccucag     1020

uagugcucgg gaacgcagcu ggacuuggua uuaugggcga guaucgaggg acacccagaa     1080

accaggaccu guacgaugcc gcuaaggccu augcagaaca guugaaagag aauggaguca     1140

ucaacuacag cgugcuagac cugacugccg aggaacucga agcuauaaag caccaacuga     1200

auccuaaaga uaacgacguu gagcuuugag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10491
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10491
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagcaaggu gaagcugaac gacacccuga acaaggacca gcugcugagc agcagcaagu      120

acaccaucca gagaagcacc ggcgacagca ucgacacccc caacuacgac gugcagaagc      180

acaucaacaa gcugugcggc augcugcuga ucaccgagga cgccaaccac aaguucaccg      240

gccugaucgg caugcuguac gccaugagca gacugggcag agaggacacc aucaagaucc      300

ugagagacgc cggcuaccac gugaaggcca acggcgugga cgugaccacc cacagacagg      360

acaucaacgg caaggagaug aaguucgagg ugcugacccu ggccagccug accaccgaga      420

uccagaucaa caucgagauc gagagcagaa agagcuacaa gaagaugcug aaggagaugg      480

gcgagguggc ccccgaguac agacacgaca gccccgacug cggcaugauc auccugugca      540

ucgccgcccu ggugaucacc aagcuggccg ccggcgacag aagcggccug accgccguga      600

ucagaagagc caacaacgug cugaagaacg agaugaagag auacaagggc cugcugccca      660

aggacaucgc caacagcuuc uacgaggugu ucgagaagca cccccacuuc aucgacgugu      720

ucgugcacuu cggcaucgcc cagagcagca ccagaggcgg cagcagagug gagggcaucu      780

ucgccggccu guucaugaac gccuacggcg ccggccaggu gaugcugaga uggggcgugc      840

uggccaagag cgugaagaac aucaugcugg gccacgccag cgugcaggcc gagauggagc      900

agguggugga gguguacgag uacgcccaga agcugggcgg cgaggccggc uucuaccaca      960

uccugaacaa ccccaaggcc agccugcuga gccugaccca guucccccac uucagcagcg     1020

uggugcuggg caacgccgcc ggccugggca ucaugggcga guacagaggc acccccagaa     1080

accaggaccu guacgacgcc gccaaggccu acgccgagca gcugaaggag aacggcguga     1140

ucaacuacag cgugcuggac cugaccgccg aggagcugga ggccaucaag caccagcuga     1200

accccaagga caacgacgug gagcugugag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10492
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10492
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagcaaggu gaaacucaac gacacccuga auaaggauca gcuucugucc ucuagcaaau      120

acacaaucca aagauccacg ggcgacucua uugauacccc caacuaugac guccagaagc      180

acaucaauaa acucugcggg augcugcuua uuacagagga ugcuaaccau aaguucaccg      240

gacugaucgg caugcucuac gccaugagcc ggcuggggcg cgaagacaca auuaagaucc      300

ugagagaugc gggauaucac guuaaagcua auggcgugga cgugaccaca caucggcagg      360

auaucaacgg gaaggagaug aaauuugaag uccucacccu ggccucccuu acgaccgaga      420

uucagaucaa uauugaaauc gagucucgca agagcuacaa aaagaugcug aaggagaugg      480

gagaaguggc cccugaguau agacacgacu ccccggauug uggcaugauu auccucugca      540

uugcugcccu gguuaucaca aaacuugcug ccggcgaccg gagcgggcug accgcgguga      600

uccgcagagc caacaauguc cucaagaacg aaaugaaacg guacaaggga cugcugccca      660

aagauauugc uaauucuuuc uaugaggugu uugagaagca uccucacuuc aucgacguuu      720

uugugcacuu cggcauugcc caauccagca cacgcggggg aucuagaguc gaaggcaucu      780

uugcuggacu cuucaugaac gccuacgggg cgggccaggu gaugcugcgg uggggcgugc      840

uugccaaauc cgucaagaau auuaugcugg ggcaugcuag cguucaggcc gagauggaac      900

agguggugga ggucuacgaa uaugcucaaa agcucggagg cgaggccggg uuuuaccaca      960

uccugaacaa ucccaaagcc ucucuucugu cccucaccca guucccucau uuuagcuccg     1020

ugguucuggg aaacgcugcg ggccugggga ucaugggaga guaucgcggc acgcccagaa     1080

accaggaccu cuacgaugcc gcuaaggccu augccgaaca gcugaaagag aauggcguga     1140

uuaacuacuc uguccuugac cugacagcug aggaacucga agccaucaag caccaacuga     1200

auccuaaaga uaacgacgug gagcuuugag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10493
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10493
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

uaagcaaagu caaauuaaac gacacauuaa acaaagacca acucuuauca ucaucaaaau      120

acacaauaca aagaagcacc ggagacagua ucgacacacc aaacuaugac guccaaaaac      180

auauaaauaa auuaugcggc augcucuuaa ucacagaaga cgccaaccau aaauuuacag      240

gauuaauagg aauguuauau gcaaugucac gacuagguag agaagacaca auaaaaauac      300

uaagagacgc aggcuaucac guaaaagcaa auggaguaga cguaaccaca cacagacaag      360

acauaaaugg aaaagaaaug aaauuugaag uauuaacacu agcaucacua acaacagaaa      420

uacaaaucaa cauagaaaua gaaucaagaa aaagcuacaa aaaaauguua aaagaaaugg      480

gagaagucgc accagaauau agacaugauu caccagacug cggaaugaua auacuaugca      540

uagcagcccu aguaauuaca aaacuagcag caggagacag aagcggauua acagcaguaa      600

uaagaagagc aaacaacgua cuaaaaaacg aaaugaaaag auauaaagga uuauuaccaa      660

aagacauagc aaacucauuc uaugaaguau ucgaaaaaca cccccacuuu auagacgucu      720

ucguacacuu cggaauagcc caaucaucca caagaggagg aucaagaguc gaaggaauau      780

ucgcaggauu auucaugaac gcauauggcg caggacaagu aaugcuaaga uggggaguac      840

uagcaaaauc cgucaaaaac auaaugcuag gacacgcauc aguucaagca gaaauggaac      900

aaguaguaga aguauacgaa uacgcccaaa aacuaggagg agaagcagga uucuaccaca      960

uacuaaauaa uccaaaagca ucacuacuaa gccuaaccca auuuccccac uucucaagug     1020

uaguauuagg aaaugcagcu ggacuaggaa uaaugggaga auacagagga acaccaagaa     1080

accaagacuu auacgacgca gcaaaagcau acgcagagca acuuaaagaa aacggaguaa     1140

uaaacuauag cguacuagac uuaacagcag aagaacugga agcaauaaaa caucaauuaa     1200

acccgaaaga caaugacgua gaauuauaag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10494
<211>  1558
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10494
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

ucucgaaagu aaaacucaac gacacccuca acaaagacca acuccuuucc agcuccaaau      120

acaccaucca acgauccacc ggagacucca ucgacacgcc caacuacgac guccagaaac      180

acaucaacaa gcucugcgga augcuacuaa ucaccgagga cgccaaccac aaauucacag      240

gacuuauagg gaugcucuac gccauguccc gccucggacg cgaagacaca auaaaaaucc      300

uacgagacgc cggcuaccac guaaaggcaa acggcgucga cgucaccaca cacagacaag      360

acaucaacgg aaaggaaaug aaauucgaag uccucacccu cgccagccua accaccgaga      420

uccaaaucaa caucgaaauc gaaucacgca aauccuacaa gaaaaugcuc aaagaaaugg      480

gagaagucgc ccccgaauac cgucacgacu cgcccgacug cggcaugaua auccuaugca      540

ucgccgcacu cgucauaacc aaacucgccg ccggugaccg aucaggacug acagcaguca      600

uccgccgagc aaacaacgug cucaaaaacg aaaugaaacg cuacaaaggc cuacucccca      660

aagacaucgc caacuccuuc uacgaagucu ucgaaaaaca cccacacuuc aucgacgucu      720

ucguccacuu cggcaucgca caaucaucaa ccagaggcgg cagccgcguu gaaggcaucu      780

ucgcaggacu cuuuaugaac gccuacggcg ccggccaagu caugcuccgc uggggcgucc      840

uggcaaaaag cgucaaaaac aucaugcuag gccacgcuag cguccaagcc gaaauggaac      900

aagucgucga aguuuacgag uacgcacaaa aacucggcgg cgaagcaggc uucuaccaca      960

uccuaaacaa ccccaaagcc ucccugcuau cacucaccca auucccccac uucuccagcg     1020

ucguccucgg caacgccgca ggacuaggca ucaugggaga auaccgcggg acaccgcgca     1080

accaagaccu cuacgacgcc gccaaagccu acgccgaaca acucaaagaa aacggcguca     1140

uaaacuacuc aguccucgac cucaccgccg aagaacucga agccaucaaa caccaacuca     1200

acccaaaaga caacgacguc gaauuauaag gacuagugca ucacauuuaa aagcaucuca     1260

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1320

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1380

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1500

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1558


<210>  10495
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (wt)

<400>  10495
gggagaaagc uuaccauggc ucuuagcaaa gucaaguuga augauacacu caacaaagau       60

caacuucugu cauccagcaa auacaccauc caacggagca caggagauag uauugauacu      120

ccuaauuaug augugcagaa acacaucaau aaguuaugug gcauguuauu aaucacagaa      180

gaugcuaauc auaaauucac uggguuaaua gguauguuau augcgauguc uagguuagga      240

agagaagaca ccauaaaaau acucagagau gcgggauauc auguaaaagc aaauggagua      300

gauguaacaa cacaucguca agacauuaau ggaaaagaaa ugaaauuuga aguguuaaca      360

uuggcaagcu uaacaacuga aauucaaauc aacauugaga uagaaucuag aaaauccuac      420

aaaaaaaugc uaaaagaaau gggagaggua gcuccagaau acaggcauga cucuccugau      480

ugugggauga uaauauuaug uauagcagca uuaguaauaa cuaaauuagc agcaggggac      540

agaucugguc uuacagccgu gauuaggaga gcuaauaaug uccuaaaaaa ugaaaugaaa      600

cguuacaaag gcuuacuacc caaggacaua gccaacagcu ucuaugaagu guuugaaaaa      660

cauccccacu uuauagaugu uuuuguucau uuugguauag cacaaucuuc uaccagaggu      720

ggcaguagag uugaagggau uuuugcagga uuguuuauga augccuaugg ugcagggcaa      780

gugauguuac gguggggagu cuuagcaaaa ucaguuaaaa auauuauguu aggacaugcu      840

agugugcaag cagaaaugga acaaguuguu gagguuuaug aauaugccca aaaauugggu      900

ggugaagcag gauucuacca uauauugaac aacccaaaag caucauuauu aucuuugacu      960

caauuuccuc acuucuccag uguaguauua ggcaaugcug cuggccuagg cauaauggga     1020

gaguacagag guacaccgag gaaucaagau cuauaugaug cagcaaaggc auaugcugaa     1080

caacucaaag aaaauggugu gauuaacuac aguguacuag acuugacagc agaagaacua     1140

gaggcuauca aacaucagcu uaauccaaaa gauaaugaug uagagcuuug aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10496
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt1) R7597

<400>  10496
gggagaaagc uuaccauggc ccugagcaag gugaagcuca acgacacccu gaacaaggac       60

cagcugcucu ccagcuccaa guacaccauc cagcgcagca ccggcgacuc caucgacacc      120

cccaacuacg acguccagaa gcacaucaac aagcugugcg ggaugcugcu caucaccgag      180

gacgccaacc acaaguucac cggccugauc gggaugcugu acgcgaugag ccggcucggc      240

cgcgaggaca cgaucaagau ccugcgggac gccggguacc acgugaaggc caacggcgug      300

gacgucacca cccaccgcca ggacaucaac ggcaaggaga ugaaguucga ggugcugacc      360

cucgccuccc ugacgaccga gauccagauc aacaucgaga ucgagagccg gaaguccuac      420

aagaagaugc ugaaggagau gggggaggug gccccggagu accgccacga cagccccgac      480

ugcggcauga ucauccucug caucgcggcc cuggucauca ccaagcuggc cgccggggac      540

cgguccggcc ucaccgcggu gauccgccgg gccaacaacg ugcugaagaa cgagaugaag      600

cgcuacaagg ggcugcuccc caaggacauc gccaacagcu ucuacgaggu cuucgagaag      660

cacccccacu ucaucgacgu guucgugcac uucggcaucg cccaguccag cacgcggggc      720

gggucccgcg ucgagggcau cuucgccggg cuguucauga acgcguacgg cgccggccag      780

gugaugcugc gguggggcgu gcucgccaag agcgucaaga acaucaugcu ggggcacgcc      840

uccgugcagg ccgagaugga gcaggucgug gagguguacg aguacgcgca gaagcucggg      900

ggcgaggccg gguucuacca cauccugaac aacccgaagg ccagccugcu gucccucacc      960

caguuccccc acuucagcag cgugguccug ggcaacgccg ccggccuggg gaucaugggc     1020

gaguaccgcg ggacgccccg gaaccaggac cucuacgacg cggccaaggc cuacgccgag     1080

cagcugaagg agaacggcgu gaucaacuac uccgugcugg accucaccgc cgaggagcug     1140

gaggcgauca agcaccagcu gaaccccaag gacaacgacg ucgagcucug aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10497
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt2)

<400>  10497
gggagaaagc uuaccauggc ccucuccaag gucaagcuca acgacacccu caacaaggac       60

cagcuccucu ccuccuccaa guacaccauc cagcgcucca ccggcgacuc caucgacacc      120

cccaacuacg acguccagaa gcacaucaac aagcucugcg gcaugcuccu caucaccgag      180

gacgccaacc acaaguucac cggccucauc ggcaugcucu acgccauguc ccgccucggc      240

cgcgaggaca ccaucaagau ccuccgcgac gccggcuacc acgucaaggc caacggcguc      300

gacgucacca cccaccgcca ggacaucaac ggcaaggaga ugaaguucga gguccucacc      360

cucgccuccc ucaccaccga gauccagauc aacaucgaga ucgagucccg caaguccuac      420

aagaagaugc ucaaggagau gggcgagguc gcccccgagu accgccacga cucccccgac      480

ugcggcauga ucauccucug caucgccgcc cucgucauca ccaagcucgc cgccggcgac      540

cgcuccggcc ucaccgccgu cauccgccgc gccaacaacg uccucaagaa cgagaugaag      600

cgcuacaagg gccuccuccc caaggacauc gccaacuccu ucuacgaggu cuucgagaag      660

cacccccacu ucaucgacgu cuucguccac uucggcaucg cccaguccuc cacccgcggc      720

ggcucccgcg ucgagggcau cuucgccggc cucuucauga acgccuacgg cgccggccag      780

gucaugcucc gcuggggcgu ccucgccaag uccgucaaga acaucaugcu cggccacgcc      840

uccguccagg ccgagaugga gcaggucguc gaggucuacg aguacgccca gaagcucggc      900

ggcgaggccg gcuucuacca cauccucaac aaccccaagg ccucccuccu cucccucacc      960

caguuccccc acuucuccuc cgucguccuc ggcaacgccg ccggccucgg caucaugggc     1020

gaguaccgcg gcaccccccg caaccaggac cucuacgacg ccgccaaggc cuacgccgag     1080

cagcucaagg agaacggcgu caucaacuac uccguccucg accucaccgc cgaggagcuc     1140

gaggccauca agcaccagcu caaccccaag gacaacgacg ucgagcucug aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10498
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt3)

<400>  10498
gggagaaagc uuaccauggc ccugagcaag gugaaacuca acgacacccu uaauaaggau       60

cagcuguugu ccucuucaaa auacacaauc caaagaagua cuggcgacag cauugauacg      120

cccaacuaug acguccagaa gcacauaaau aaauuaugcg ggaugcugcu aaucaccgag      180

gaugcuaacc auaaguucac aggacucauu gguaugcugu acgcaauguc caggcuuggc      240

cgggaagaca cuaucaagau ucugcgcgau gccggguauc acguuaaagc gaauggagug      300

gacguaacca cacaucgaca ggauaucaac ggcaaggaga ugaaauuuga aguguugacc      360

cucgcuucuc ugacuacaga gauacagauc aauauugaaa ucgagucgcg uaagucauac      420

aaaaagaugc ugaaggagau gggugaaguc gccccugagu auagacacga cagcccagau      480

ugugggauga uuauccucug cauagcagcc uuagugauua ccaaacuggc ugcaggagac      540

aggaguggcc uuacggccgu uauccggcgc gcuaacaaug uguugaagaa cgaaaugaaa      600

agauacaagg gccugcuacc gaaagauauu gccaauuccu ucuaugaggu cuuugagaag      660

cauccccacu ucaucgacgu guuuguacac uucgggaucg cgcaaucuag cacuagggga      720

gguucccggg uugaaggcau uuuugcagga cucuucauga acgccuacgg ggcuggccag      780

gugaugcugc gcuggggugu ccuugccaaa ucagugaaga auauaaugcu ggggcaugca      840

agugugcagg cugagaugga acaggucguu gagguguacg aauaugccca aaaguuggga      900

ggcgaggcgg gcuuuuacca cauccucaac aauccuaaag ccagccuguu aucucugacc      960

caguucccac auuuuuccuc aguagugcuc gggaacgcag cuggacuugg uauuaugggc     1020

gaguaucgag ggacacccag aaaccaggac cuguacgaug ccgcuaaggc cuaugcagaa     1080

caguugaaag agaauggagu caucaacuac agcgugcuag accugacugc cgaggaacuc     1140

gaagcuauaa agcaccaacu gaauccuaaa gauaacgacg uugagcuuug aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10499
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt4)

<400>  10499
gggagaaagc uuaccauggc ccugagcaag gugaagcuga acgacacccu gaacaaggac       60

cagcugcuga gcagcagcaa guacaccauc cagagaagca ccggcgacag caucgacacc      120

cccaacuacg acgugcagaa gcacaucaac aagcugugcg gcaugcugcu gaucaccgag      180

gacgccaacc acaaguucac cggccugauc ggcaugcugu acgccaugag cagacugggc      240

agagaggaca ccaucaagau ccugagagac gccggcuacc acgugaaggc caacggcgug      300

gacgugacca cccacagaca ggacaucaac ggcaaggaga ugaaguucga ggugcugacc      360

cuggccagcc ugaccaccga gauccagauc aacaucgaga ucgagagcag aaagagcuac      420

aagaagaugc ugaaggagau gggcgaggug gcccccgagu acagacacga cagccccgac      480

ugcggcauga ucauccugug caucgccgcc cuggugauca ccaagcuggc cgccggcgac      540

agaagcggcc ugaccgccgu gaucagaaga gccaacaacg ugcugaagaa cgagaugaag      600

agauacaagg gccugcugcc caaggacauc gccaacagcu ucuacgaggu guucgagaag      660

cacccccacu ucaucgacgu guucgugcac uucggcaucg cccagagcag caccagaggc      720

ggcagcagag uggagggcau cuucgccggc cuguucauga acgccuacgg cgccggccag      780

gugaugcuga gauggggcgu gcuggccaag agcgugaaga acaucaugcu gggccacgcc      840

agcgugcagg ccgagaugga gcagguggug gagguguacg aguacgccca gaagcugggc      900

ggcgaggccg gcuucuacca cauccugaac aaccccaagg ccagccugcu gagccugacc      960

caguuccccc acuucagcag cguggugcug ggcaacgccg ccggccuggg caucaugggc     1020

gaguacagag gcacccccag aaaccaggac cuguacgacg ccgccaaggc cuacgccgag     1080

cagcugaagg agaacggcgu gaucaacuac agcgugcugg accugaccgc cgaggagcug     1140

gaggccauca agcaccagcu gaaccccaag gacaacgacg uggagcugug aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10500
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt5)

<400>  10500
gggagaaagc uuaccauggc ccugagcaag gugaaacuca acgacacccu gaauaaggau       60

cagcuucugu ccucuagcaa auacacaauc caaagaucca cgggcgacuc uauugauacc      120

cccaacuaug acguccagaa gcacaucaau aaacucugcg ggaugcugcu uauuacagag      180

gaugcuaacc auaaguucac cggacugauc ggcaugcucu acgccaugag ccggcugggg      240

cgcgaagaca caauuaagau ccugagagau gcgggauauc acguuaaagc uaauggcgug      300

gacgugacca cacaucggca ggauaucaac gggaaggaga ugaaauuuga aguccucacc      360

cuggccuccc uuacgaccga gauucagauc aauauugaaa ucgagucucg caagagcuac      420

aaaaagaugc ugaaggagau gggagaagug gccccugagu auagacacga cuccccggau      480

uguggcauga uuauccucug cauugcugcc cugguuauca caaaacuugc ugccggcgac      540

cggagcgggc ugaccgcggu gauccgcaga gccaacaaug uccucaagaa cgaaaugaaa      600

cgguacaagg gacugcugcc caaagauauu gcuaauucuu ucuaugaggu guuugagaag      660

cauccucacu ucaucgacgu uuuugugcac uucggcauug cccaauccag cacacgcggg      720

ggaucuagag ucgaaggcau cuuugcugga cucuucauga acgccuacgg ggcgggccag      780

gugaugcugc gguggggcgu gcuugccaaa uccgucaaga auauuaugcu ggggcaugcu      840

agcguucagg ccgagaugga acagguggug gaggucuacg aauaugcuca aaagcucgga      900

ggcgaggccg gguuuuacca cauccugaac aaucccaaag ccucucuucu gucccucacc      960

caguucccuc auuuuagcuc cgugguucug ggaaacgcug cgggccuggg gaucauggga     1020

gaguaucgcg gcacgcccag aaaccaggac cucuacgaug ccgcuaaggc cuaugccgaa     1080

cagcugaaag agaauggcgu gauuaacuac ucuguccuug accugacagc ugaggaacuc     1140

gaagccauca agcaccaacu gaauccuaaa gauaacgacg uggagcuuug aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10501
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt6)

<400>  10501
gggagaaagc uuaccauggc acuaagcaaa gucaaauuaa acgacacauu aaacaaagac       60

caacucuuau caucaucaaa auacacaaua caaagaagca ccggagacag uaucgacaca      120

ccaaacuaug acguccaaaa acauauaaau aaauuaugcg gcaugcucuu aaucacagaa      180

gacgccaacc auaaauuuac aggauuaaua ggaauguuau augcaauguc acgacuaggu      240

agagaagaca caauaaaaau acuaagagac gcaggcuauc acguaaaagc aaauggagua      300

gacguaacca cacacagaca agacauaaau ggaaaagaaa ugaaauuuga aguauuaaca      360

cuagcaucac uaacaacaga aauacaaauc aacauagaaa uagaaucaag aaaaagcuac      420

aaaaaaaugu uaaaagaaau gggagaaguc gcaccagaau auagacauga uucaccagac      480

ugcggaauga uaauacuaug cauagcagcc cuaguaauua caaaacuagc agcaggagac      540

agaagcggau uaacagcagu aauaagaaga gcaaacaacg uacuaaaaaa cgaaaugaaa      600

agauauaaag gauuauuacc aaaagacaua gcaaacucau ucuaugaagu auucgaaaaa      660

cacccccacu uuauagacgu cuucguacac uucggaauag cccaaucauc cacaagagga      720

ggaucaagag ucgaaggaau auucgcagga uuauucauga acgcauaugg cgcaggacaa      780

guaaugcuaa gauggggagu acuagcaaaa uccgucaaaa acauaaugcu aggacacgca      840

ucaguucaag cagaaaugga acaaguagua gaaguauacg aauacgccca aaaacuagga      900

ggagaagcag gauucuacca cauacuaaau aauccaaaag caucacuacu aagccuaacc      960

caauuucccc acuucucaag uguaguauua ggaaaugcag cuggacuagg aauaauggga     1020

gaauacagag gaacaccaag aaaccaagac uuauacgacg cagcaaaagc auacgcagag     1080

caacuuaaag aaaacggagu aauaaacuau agcguacuag acuuaacagc agaagaacug     1140

gaagcaauaa aacaucaauu aaacccgaaa gacaaugacg uagaauuaua aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10502
<211>  1393
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03418.1__N (opt11)

<400>  10502
gggagaaagc uuaccauggc acucucgaaa guaaaacuca acgacacccu caacaaagac       60

caacuccuuu ccagcuccaa auacaccauc caacgaucca ccggagacuc caucgacacg      120

cccaacuacg acguccagaa acacaucaac aagcucugcg gaaugcuacu aaucaccgag      180

gacgccaacc acaaauucac aggacuuaua gggaugcucu acgccauguc ccgccucgga      240

cgcgaagaca caauaaaaau ccuacgagac gccggcuacc acguaaaggc aaacggcguc      300

gacgucacca cacacagaca agacaucaac ggaaaggaaa ugaaauucga aguccucacc      360

cucgccagcc uaaccaccga gauccaaauc aacaucgaaa ucgaaucacg caaauccuac      420

aagaaaaugc ucaaagaaau gggagaaguc gcccccgaau accgucacga cucgcccgac      480

ugcggcauga uaauccuaug caucgccgca cucgucauaa ccaaacucgc cgccggugac      540

cgaucaggac ugacagcagu cauccgccga gcaaacaacg ugcucaaaaa cgaaaugaaa      600

cgcuacaaag gccuacuccc caaagacauc gccaacuccu ucuacgaagu cuucgaaaaa      660

cacccacacu ucaucgacgu cuucguccac uucggcaucg cacaaucauc aaccagaggc      720

ggcagccgcg uugaaggcau cuucgcagga cucuuuauga acgccuacgg cgccggccaa      780

gucaugcucc gcuggggcgu ccuggcaaaa agcgucaaaa acaucaugcu aggccacgcu      840

agcguccaag ccgaaaugga acaagucguc gaaguuuacg aguacgcaca aaaacucggc      900

ggcgaagcag gcuucuacca cauccuaaac aaccccaaag ccucccugcu aucacucacc      960

caauuccccc acuucuccag cgucguccuc ggcaacgccg caggacuagg caucauggga     1020

gaauaccgcg ggacaccgcg caaccaagac cucuacgacg ccgccaaagc cuacgccgaa     1080

caacucaaag aaaacggcgu cauaaacuac ucaguccucg accucaccgc cgaagaacuc     1140

gaagccauca aacaccaacu caacccaaaa gacaacgacg ucgaauuaua aggacuaguu     1200

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1260

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1380

agccaccaga auu                                                        1393


<210>  10503
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(Memphis-37)__AIY60635.1__N

<400>  10503

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10504
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__O42053.1__N

<400>  10504

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10505
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAC55964.1__N

<400>  10505

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Ile Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10506
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAR14261.1__N

<400>  10506

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10507
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABG81855.1__N

<400>  10507

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Ser Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10508
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABG81856.1__N

<400>  10508

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Pro Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Arg Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10509
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABG81857.1__N

<400>  10509

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10510
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABG81859.1__N

<400>  10510

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Gln Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10511
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ABG81860.1__N

<400>  10511

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Cys Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10512
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45825.1__N

<400>  10512

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10513
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45884.1__N

<400>  10513

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Phe Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10514
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45904.1__N

<400>  10514

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10515
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45914.1__N

<400>  10515

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10516
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEO45924.1__N

<400>  10516

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Asp Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10517
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63439.1__N

<400>  10517

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala His Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10518
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63515.1__N

<400>  10518

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10519
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63581.1__N

<400>  10519

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10520
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AEQ63625.1__N

<400>  10520

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Ile Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10521
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFI25257.1__N

<400>  10521

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Thr Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10522
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55228.1__N

<400>  10522

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Thr Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10523
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55250.1__N

<400>  10523

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Thr Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10524
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55283.1__N

<400>  10524

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Ile 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10525
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55514.1__N

<400>  10525

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp His 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Val Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10526
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM55547.1__N

<400>  10526

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10527
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFM95360.1__N

<400>  10527

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Ile Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10528
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AFX95846.1__N

<400>  10528

Met Ala Pro Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Pro Pro Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Thr Asp Thr Pro Asn Tyr Asp Val Gln Lys His Thr Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10529
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28666.1__N

<400>  10529

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Thr Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10530
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGN28787.1__N

<400>  10530

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10531
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AGT75341.1__N

<400>  10531

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Tyr 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10532
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83645.1__N

<400>  10532

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Ala Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10533
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83744.1__N

<400>  10533

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Thr Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10534
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHA83919.1__N

<400>  10534

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Ile Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10535
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHB33450.1__N

<400>  10535

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Phe Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10536
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHC94758.1__N

<400>  10536

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Ala Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10537
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80753.1__N

<400>  10537

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Leu Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Glu Asp Val Glu Leu 
385                 390     


<210>  10538
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV80798.1__N

<400>  10538

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10539
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81073.1__N

<400>  10539

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Glu Asp Val Glu Leu 
385                 390     


<210>  10540
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81084.1__N

<400>  10540

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Gly Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10541
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81237.1__N

<400>  10541

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Ala Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10542
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81292.1__N

<400>  10542

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Ala Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10543
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81457.1__N

<400>  10543

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Val Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10544
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHV81677.1__N

<400>  10544

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Leu Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10545
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80506.1__N

<400>  10545

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Arg Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10546
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80735.1__N

<400>  10546

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu His Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10547
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80745.1__N

<400>  10547

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu His Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Thr Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10548
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80795.1__N

<400>  10548

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10549
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW80935.1__N

<400>  10549

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Thr Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10550
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81055.1__N

<400>  10550

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Ala Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10551
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHW81295.1__N

<400>  10551

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Lys Lys Asn 
            180                 185                 190         


Lys Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10552
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57191.1__N

<400>  10552

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Arg Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10553
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHX57554.1__N

<400>  10553

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Ile Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10554
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21293.1__N

<400>  10554

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Ile Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10555
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21326.1__N

<400>  10555

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Ala Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10556
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21392.1__N

<400>  10556

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Thr Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10557
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AHY21425.1__N

<400>  10557

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Ile His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10558
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA62740.1__N

<400>  10558

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Asn Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10559
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA62979.1__N

<400>  10559

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Glu His 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10560
<211>  388
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIA63399.1__N

<400>  10560

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Ile Phe Leu Thr Glu Ile Gln Ile Asn Ile Glu Ile Glu Ser 
        115                 120                 125             


Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu Val Ala Pro 
    130                 135                 140                 


Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile Leu Cys Ile 
145                 150                 155                 160 


Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg Ser Gly Leu 
                165                 170                 175     


Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn Glu Met Lys 
            180                 185                 190         


Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser Phe Tyr Glu 
        195                 200                 205             


Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val His Phe Gly 
    210                 215                 220                 


Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu Gly Ile Phe 
225                 230                 235                 240 


Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val Met Leu Arg 
                245                 250                 255     


Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu Gly His Ala 
            260                 265                 270         


Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr Glu Tyr Ala 
        275                 280                 285             


Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu Asn Asn Pro 
    290                 295                 300                 


Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe Ser Ser Val 
305                 310                 315                 320 


Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu Tyr Arg Gly 
                325                 330                 335     


Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala Tyr Ala Glu 
            340                 345                 350         


Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu Asp Leu Thr 
        355                 360                 365             


Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro Lys Asp Asn 
    370                 375                 380                 


Asp Val Glu Leu 
385             


<210>  10561
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY62423.1__N

<400>  10561

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10562
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIY70193.1__N

<400>  10562

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Gly 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10563
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95602.1__N

<400>  10563

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Thr Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10564
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95624.1__N

<400>  10564

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10565
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95646.1__N

<400>  10565

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Lys Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10566
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95866.1__N

<400>  10566

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Thr Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10567
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AIZ95943.1__N

<400>  10567

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Thr Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Leu Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10568
<211>  390
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44633.1__N

<400>  10568

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Lys Asp Gln Leu 
1               5                   10                  15      


Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser Ile 
            20                  25                  30          


Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys Gly 
        35                  40                  45              


Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val Ile 
    50                  55                  60                  


Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile Lys 
65                  70                  75                  80  


Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp Val 
                85                  90                  95      


Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu Val 
            100                 105                 110         


Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu Ile 
        115                 120                 125             


Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu Val 
    130                 135                 140                 


Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile Leu 
145                 150                 155                 160 


Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg Ser 
                165                 170                 175     


Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn Glu 
            180                 185                 190         


Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser Phe 
        195                 200                 205             


Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val His 
    210                 215                 220                 


Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu Gly 
225                 230                 235                 240 


Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val Met 
                245                 250                 255     


Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu Gly 
            260                 265                 270         


His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr Glu 
        275                 280                 285             


Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu Asn 
    290                 295                 300                 


Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe Ser 
305                 310                 315                 320 


Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu Tyr 
                325                 330                 335     


Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala Tyr 
            340                 345                 350         


Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu Asp 
        355                 360                 365             


Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro Lys 
    370                 375                 380                 


Asp Asn Asp Val Glu Leu 
385                 390 


<210>  10569
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44638.1__N

<400>  10569

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10570
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJF44733.1__N

<400>  10570

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Thr Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10571
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJO16072.1__N

<400>  10571

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Val Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Val Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10572
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69864.1__N

<400>  10572

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg His Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10573
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ69875.1__N

<400>  10573

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10574
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AJZ70062.1__N

<400>  10574

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Asp 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10575
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AKA45811.1__N

<400>  10575

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Asp Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10576
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66531.1__N

<400>  10576

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Ala Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10577
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66564.1__N

<400>  10577

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Ser Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10578
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66575.1__N

<400>  10578

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Ala Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10579
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66619.1__N

<400>  10579

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Leu Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Ala Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10580
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66806.1__N

<400>  10580

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys Asn Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10581
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA66817.1__N

<400>  10581

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Glu Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10582
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67092.1__N

<400>  10582

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Met Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10583
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67235.1__N

<400>  10583

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Ile Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10584
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67323.1__N

<400>  10584

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10585
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMA67334.1__N

<400>  10585

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Met Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10586
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMN91424.1__N

<400>  10586

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Arg Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10587
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77353.1__N

<400>  10587

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Ser Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10588
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77518.1__N

<400>  10588

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Ile Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10589
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77639.1__N

<400>  10589

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Thr Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10590
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT77727.1__N

<400>  10590

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Asn Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10591
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78035.1__N

<400>  10591

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Ser Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10592
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78068.1__N

<400>  10592

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Thr Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10593
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT78431.1__N

<400>  10593

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Met 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10594
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79185.1__N

<400>  10594

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


His Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10595
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79262.1__N

<400>  10595

Met Ala Leu Ser Lys Val Arg Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10596
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79383.1__N

<400>  10596

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Arg Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10597
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AMT79592.1__N

<400>  10597

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Ile Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Gly Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10598
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80095.1__N

<400>  10598

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Ala Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10599
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ANZ80414.1__N

<400>  10599

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Asp Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10600
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48678.1__N

<400>  10600

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10601
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48711.1__N

<400>  10601

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Val 
    50                  55                  60                  


Val Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10602
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS48854.1__N

<400>  10602

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Val Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10603
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS49151.1__N

<400>  10603

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Ile Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10604
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AOS49173.1__N

<400>  10604

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Val Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10605
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78620.1__N

<400>  10605

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Val Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10606
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78631.1__N

<400>  10606

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Leu Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10607
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78697.1__N

<400>  10607

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Arg Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Thr Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10608
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78763.1__N

<400>  10608

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10609
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78829.1__N

<400>  10609

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Lys Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10610
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78884.1__N

<400>  10610

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Val Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10611
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__APW78895.1__N

<400>  10611

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asn Asp Val Glu Leu 
385                 390     


<210>  10612
<211>  389
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AQX36836.1__N

<400>  10612

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Met 
385                 


<210>  10613
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB66400.1__N

<400>  10613

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Trp 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10614
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARB66422.1__N

<400>  10614

Met Ala Pro Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10615
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29184.1__N

<400>  10615

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10616
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ARR29246.1__N

<400>  10616

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Val Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10617
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28302.1__N

<400>  10617

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Ser Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10618
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ART28389.1__N

<400>  10618

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Arg Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10619
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASK05515.1__N

<400>  10619

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10620
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASV49527.1__N

<400>  10620

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Asn His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10621
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASV65822.1__N

<400>  10621

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ser Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10622
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__ASZ70094.1__N

<400>  10622

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Asp Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Thr Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10623
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68067.1__N

<400>  10623

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Ile Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10624
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68089.1__N

<400>  10624

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ala Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Thr Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10625
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68221.1__N

<400>  10625

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Asp Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10626
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUC68473.1__N

<400>  10626

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Ser Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10627
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AUH15159.1__N

<400>  10627

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Asp 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10628
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BAE96916.1__N

<400>  10628

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Arg Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10629
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__BBA57885.1__N

<400>  10629

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Val Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10630
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__CAI96788.1__N

<400>  10630

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Phe Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Thr Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Ile Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Leu 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr Gln Val Arg Ala Asn Gly Val Asp 
                85                  90                  95      


Val Ile Thr His Arg Gln Asp Val Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Val Ser Leu Thr Ser Glu Val Gln Gly Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Phe Arg His Asp Ser Pro Asp Cys Gly Met Ile Val 
145                 150                 155                 160 


Leu Cys Val Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Arg Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Tyr Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Gly Ser 
385                 390     


<210>  10631
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__NP_044591.1__N

<400>  10631

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Ser 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Ile Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Thr Thr His Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Thr Glu Ile Gln Ile Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Leu Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Phe Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro His Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10632
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P22677.1__N

<400>  10632

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Phe Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Thr Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Ile Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Ile Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Leu 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr Gln Val Arg Ala Asn Gly Val Asp 
                85                  90                  95      


Val Ile Thr His Arg Gln Asp Val Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Val Ser Leu Thr Ser Glu Val Gln Gly Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Val 
145                 150                 155                 160 


Leu Cys Val Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Arg Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Ile Glu Lys Tyr Pro His Tyr Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10633
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P24566.1__N

<400>  10633

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Leu Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Ser Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Thr Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Ile 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr His Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Ile Thr Thr Tyr Arg Gln Asp Ile Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Ser Ser Leu Thr Ser Glu Ile Gln Val Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Leu Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Ile 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys His Pro His Leu Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ser Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Ala Glu Glu Leu Glu Ala Ile Lys His Gln Leu Asn Pro 
    370                 375                 380                 


Lys Glu Asp Asp Val Glu Leu 
385                 390     


<210>  10634
<211>  393
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P26589.1__N

<400>  10634

Met Ser Leu Asp Arg Leu Lys Leu Asn Asp Val Ser Asn Lys Asp Ser 
1               5                   10                  15      


Leu Leu Ser Asn Cys Lys Tyr Ser Val Thr Arg Ser Thr Gly Asp Val 
            20                  25                  30          


Thr Ser Val Ser Gly His Ala Met Gln Lys Ala Leu Ala Arg Thr Leu 
        35                  40                  45              


Gly Met Phe Leu Leu Thr Ala Phe Asn Arg Cys Glu Glu Val Ala Glu 
    50                  55                  60                  


Ile Gly Leu Gln Tyr Ala Met Ser Leu Leu Gly Arg Asp Asp Ser Ile 
65                  70                  75                  80  


Lys Ile Leu Arg Glu Ala Gly Tyr Asn Val Lys Cys Val Asp Thr Gln 
                85                  90                  95      


Leu Lys Asp Phe Thr Ile Lys Leu Gln Gly Lys Glu Tyr Lys Ile Gln 
            100                 105                 110         


Val Leu Asp Ile Val Gly Ile Asp Ala Ala Asn Leu Ala Asp Leu Glu 
        115                 120                 125             


Ile Gln Ala Arg Gly Val Val Ala Lys Glu Leu Lys Thr Gly Ala Arg 
    130                 135                 140                 


Leu Pro Asp Asn Arg Arg His Asp Ala Pro Asp Cys Gly Val Ile Val 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Val Ser Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Gly Gly Leu Asp Ala Val Glu Arg Arg Ala Leu Asn Val Leu Lys Ala 
            180                 185                 190         


Glu Lys Ala Arg Tyr Pro Asn Met Glu Val Lys Gln Ile Ala Glu Ser 
        195                 200                 205             


Phe Tyr Asp Leu Phe Glu Arg Lys Pro Tyr Tyr Ile Asp Val Phe Ile 
    210                 215                 220                 


Thr Phe Gly Leu Ala Gln Ser Ser Val Arg Gly Gly Ser Lys Val Glu 
225                 230                 235                 240 


Gly Leu Phe Ser Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Leu Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Gln Gly Gly Glu Ala Gly Phe Tyr His Ile Arg 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Asn Cys Pro Asn Phe 
305                 310                 315                 320 


Thr Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Ile Gly Ser 
                325                 330                 335     


Tyr Lys Gly Ala Pro Arg Asn Arg Glu Leu Phe Asp Ala Ala Lys Asp 
            340                 345                 350         


Tyr Ala Glu Arg Leu Lys Asp Asn Asn Val Ile Asn Tyr Ser Ala Leu 
        355                 360                 365             


Asn Leu Thr Ala Glu Glu Arg Glu Leu Ile Ser Gln Gln Leu Asn Ile 
    370                 375                 380                 


Val Asp Asp Thr Pro Asp Asp Asp Ile 
385                 390             


<210>  10635
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__P35943.1__N

<400>  10635

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Phe Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Thr Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Ile Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Leu 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr Gln Val Arg Ala Asn Gly Val Asp 
                85                  90                  95      


Val Ile Thr His Arg Gln Asp Val Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Val Ser Leu Thr Ser Glu Val Gln Gly Asn Ile Glu 
        115                 120                 125             


Ile Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Phe Pro Asp Cys Gly Met Ile Val 
145                 150                 155                 160 


Leu Cys Val Ala Ala Leu Val Ile Thr Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Arg Asn 
            180                 185                 190         


Glu Met Lys Arg Tyr Lys Gly Leu Ile Pro Lys Asp Ile Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Tyr Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10636
<211>  391
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__Q83957.1__N

<400>  10636

Met Ala Leu Ser Lys Val Lys Leu Asn Asp Thr Phe Asn Lys Asp Gln 
1               5                   10                  15      


Leu Leu Ser Thr Ser Lys Tyr Thr Ile Gln Arg Ser Thr Gly Asp Asn 
            20                  25                  30          


Ile Asp Ile Pro Asn Tyr Asp Val Gln Lys His Leu Asn Lys Leu Cys 
        35                  40                  45              


Gly Met Leu Leu Ile Thr Glu Asp Ala Asn His Lys Phe Thr Gly Leu 
    50                  55                  60                  


Ile Gly Met Leu Tyr Ala Met Ser Arg Leu Gly Arg Glu Asp Thr Leu 
65                  70                  75                  80  


Lys Ile Leu Lys Asp Ala Gly Tyr Gln Val Lys Ala Asn Gly Val Asp 
                85                  90                  95      


Val Ile Thr His Arg Gln Asp Val Asn Gly Lys Glu Met Lys Phe Glu 
            100                 105                 110         


Val Leu Thr Leu Val Ser Leu Thr Ser Glu Val Gln Val Asn Ile Glu 
        115                 120                 125             


Val Glu Ser Arg Lys Ser Tyr Lys Lys Met Leu Lys Glu Met Gly Glu 
    130                 135                 140                 


Val Ala Pro Glu Tyr Arg His Asp Ser Pro Asp Cys Gly Met Ile Val 
145                 150                 155                 160 


Leu Cys Ile Ala Ala Leu Val Ile Ala Lys Leu Ala Ala Gly Asp Arg 
                165                 170                 175     


Ser Gly Leu Thr Ala Val Ile Arg Arg Ala Asn Asn Val Leu Lys Asn 
            180                 185                 190         


Glu Ile Glu Arg Tyr Lys Gly Leu Ile Pro Lys Asp Val Ala Asn Ser 
        195                 200                 205             


Phe Tyr Glu Val Phe Glu Lys Tyr Pro His Tyr Ile Asp Val Phe Val 
    210                 215                 220                 


His Phe Gly Ile Ala Gln Ser Ser Thr Arg Gly Gly Ser Arg Val Glu 
225                 230                 235                 240 


Gly Ile Phe Ala Gly Leu Phe Met Asn Ala Tyr Gly Ala Gly Gln Val 
                245                 250                 255     


Met Leu Arg Trp Gly Val Leu Ala Lys Ser Val Lys Asn Ile Met Leu 
            260                 265                 270         


Gly His Ala Ser Val Gln Ala Glu Met Glu Gln Val Val Glu Val Tyr 
        275                 280                 285             


Glu Tyr Ala Gln Lys Leu Gly Gly Glu Ala Gly Phe Tyr His Ile Leu 
    290                 295                 300                 


Asn Asn Pro Lys Ala Ser Leu Leu Ser Leu Thr Gln Phe Pro Asn Phe 
305                 310                 315                 320 


Ser Ser Val Val Leu Gly Asn Ala Ala Gly Leu Gly Ile Met Gly Glu 
                325                 330                 335     


Tyr Arg Gly Thr Pro Arg Asn Gln Asp Leu Tyr Asp Ala Ala Lys Ala 
            340                 345                 350         


Tyr Ala Glu Gln Leu Lys Glu Asn Gly Val Ile Asn Tyr Ser Val Leu 
        355                 360                 365             


Asp Leu Thr Thr Glu Glu Leu Glu Ala Ile Lys Asn Gln Leu Asn Pro 
    370                 375                 380                 


Lys Asp Asn Asp Val Glu Leu 
385                 390     


<210>  10637
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(A2)__P03421.1__P

<400>  10637

Met Glu Lys Phe Ala Pro Glu Phe His Gly Glu Asp Ala Asn Asn Arg 
1               5                   10                  15      


Ala Thr Lys Phe Leu Glu Ser Ile Lys Gly Lys Phe Thr Ser Pro Lys 
            20                  25                  30          


Asp Pro Lys Lys Lys Asp Ser Ile Ile Ser Val Asn Ser Ile Asp Ile 
        35                  40                  45              


Glu Val Thr Lys Glu Ser Pro Ile Thr Ser Asn Ser Thr Ile Ile Asn 
    50                  55                  60                  


Pro Thr Asn Glu Thr Asp Asp Thr Ala Gly Asn Lys Pro Asn Tyr Gln 
65                  70                  75                  80  


Arg Lys Pro Leu Val Ser Phe Lys Glu Asp Pro Thr Pro Ser Asp Asn 
                85                  90                  95      


Pro Phe Ser Lys Leu Tyr Lys Glu Thr Ile Glu Thr Phe Asp Asn Asn 
            100                 105                 110         


Glu Glu Glu Ser Ser Tyr Ser Tyr Glu Glu Ile Asn Asp Gln Thr Asn 
        115                 120                 125             


Asp Asn Ile Thr Ala Arg Leu Asp Arg Ile Asp Glu Lys Leu Ser Glu 
    130                 135                 140                 


Ile Leu Gly Met Leu His Thr Leu Val Val Ala Ser Ala Gly Pro Thr 
145                 150                 155                 160 


Ser Ala Arg Asp Gly Ile Arg Asp Ala Met Ile Gly Leu Arg Glu Glu 
                165                 170                 175     


Met Ile Glu Lys Ile Arg Thr Glu Ala Leu Met Thr Asn Asp Arg Leu 
            180                 185                 190         


Glu Ala Met Ala Arg Leu Arg Asn Glu Glu Ser Glu Lys Met Ala Lys 
        195                 200                 205             


Asp Thr Ser Asp Glu Val Ser Leu Asn Pro Thr Ser Glu Lys Leu Asn 
    210                 215                 220                 


Asn Leu Leu Glu Gly Asn Asp Ser Asp Asn Asp Leu Ser Leu Glu Asp 
225                 230                 235                 240 


Phe 
    


<210>  10638
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from 
       HRSV(A2)__P03421.1__P

<400>  10638
auggaaaagu uugcuccuga auuccaugga gaagaugcaa acaacagggc uacuaaauuc       60

cuagaaucaa uaaagggcaa auucacauca cccaaagauc ccaagaaaaa agauaguauc      120

auaucuguca acucaauaga uauagaagua accaaagaaa gcccuauaac aucaaauuca      180

acuauuauca acccaacaaa ugagacagau gauacugcag ggaacaagcc caauuaucaa      240

agaaaaccuc uaguaaguuu caaagaagac ccuacaccaa gugauaaucc cuuuucuaaa      300

cuauacaaag aaaccauaga aacauuugau aacaaugaag aagaauccag cuauucauac      360

gaagaaauaa augaucagac aaacgauaau auaacagcaa gauuagauag gauugaugaa      420

aaauuaagug aaauacuagg aaugcuucac acauuaguag uggcaagugc aggaccuaca      480

ucugcucggg augguauaag agaugccaug auugguuuaa gagaagaaau gauagaaaaa      540

aucagaacug aagcauuaau gaccaaugac agauuagaag cuauggcaag acucaggaau      600

gaggaaagug aaaagauggc aaaagacaca ucagaugaag ugucucucaa uccaacauca      660

gagaaauuga acaaccuauu ggaagggaau gauagugaca augaucuauc acuugaagau      720

uucuga                                                                 726


<210>  10639
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       HRSV(A2)__P03421.1__P

<400>  10639
auggagaagu ucgcccccga guuccacggc gaggacgcca acaaccgcgc gaccaaguuc       60

cuggagagca ucaaggggaa guucaccucc ccgaaggacc ccaagaagaa ggacagcauc      120

aucuccguga acagcaucga caucgagguc acgaaggagu cccccaucac cagcaacucc      180

accaucauca accccaccaa cgagacggac gacaccgccg gcaacaagcc gaacuaccag      240

cggaagcccc ucgugagcuu caaggaggac cccacccccu ccgacaaccc guucagcaag      300

cuguacaagg agaccaucga gacguucgac aacaacgagg aggaguccag cuacuccuac      360

gaggagauca acgaccagac caacgacaac aucaccgccc gccuggaccg gaucgacgag      420

aagcucagcg agauccuggg gaugcugcac acccucgugg ucgccuccgc cggccccacg      480

agcgcgcgcg acgggauccg ggacgccaug aucggccugc gcgaggagau gaucgagaag      540

auccggaccg aggcccugau gaccaacgac cgccucgagg ccauggcgcg gcugcgcaac      600

gaggaguccg agaagauggc caaggacacc agcgacgagg ugucccugaa ccccacgagc      660

gagaagcuca acaaccugcu ggagggcaac gacagcgaca acgaccucuc ccuggaggac      720

uucuga                                                                 726


<210>  10640
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       HRSV(A2)__P03421.1__P

<400>  10640
auggagaagu ucgcccccga guuccacggc gaggacgcca acaaccgcgc caccaaguuc       60

cucgagucca ucaagggcaa guucaccucc cccaaggacc ccaagaagaa ggacuccauc      120

aucuccguca acuccaucga caucgagguc accaaggagu cccccaucac cuccaacucc      180

accaucauca accccaccaa cgagaccgac gacaccgccg gcaacaagcc caacuaccag      240

cgcaagcccc ucgucuccuu caaggaggac cccacccccu ccgacaaccc cuucuccaag      300

cucuacaagg agaccaucga gaccuucgac aacaacgagg aggaguccuc cuacuccuac      360

gaggagauca acgaccagac caacgacaac aucaccgccc gccucgaccg caucgacgag      420

aagcucuccg agauccucgg caugcuccac acccucgucg ucgccuccgc cggccccacc      480

uccgcccgcg acggcauccg cgacgccaug aucggccucc gcgaggagau gaucgagaag      540

auccgcaccg aggcccucau gaccaacgac cgccucgagg ccauggcccg ccuccgcaac      600

gaggaguccg agaagauggc caaggacacc uccgacgagg ucucccucaa ccccaccucc      660

gagaagcuca acaaccuccu cgagggcaac gacuccgaca acgaccucuc ccucgaggac      720

uucuga                                                                 726


<210>  10641
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       HRSV(A2)__P03421.1__P

<400>  10641
auggagaagu ucgcccccga auuucacggc gaggacgcua acaauagagc aaccaaauuc       60

cuggaaagca ucaaggggaa auuuacaucc ccuaaggauc cgaaaaagaa ggacucuauu      120

auaucaguga acaguaucga uauugagguc acuaaagaaa gcccaaucac guccaauucu      180

accauuauca accccacaaa ugagacugac gauaccgccg gaaacaagcc uaauuaccag      240

aggaaaccac ucguuucguu caaggaggac cccacaccuu cagauaaccc auuuagcaaa      300

cuuuauaagg aaaccauaga gacuuucgac aauaacgaag aggagaguuc cuacucuuau      360

gaagagauca augaucaaac aaacgacaau auuaccgcgc ggcuggaucg caucgacgaa      420

aaguugagcg agauuuuagg uaugcugcau acgcuagugg uagcuuccgc cggccccacu      480

ucagcacgag augggauccg ugacgccaug auaggacuca gagaagagau gauugagaaa      540

aucaggaccg aagcucugau gacaaacgac cggcuugagg caauggcccg ccugagaaau      600

gaagagagug aaaagauggc uaaagauacu agcgacgagg ugucuuugaa cccuaccucc      660

gagaagcuca acaaucugcu ggaaggcaac gauucagaca augaucucag cuuagaggac      720

uuuuga                                                                 726


<210>  10642
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       HRSV(A2)__P03421.1__P

<400>  10642
auggagaagu ucgcccccga guuccacggc gaggacgcca acaacagagc caccaaguuc       60

cuggagagca ucaagggcaa guucaccagc cccaaggacc ccaagaagaa ggacagcauc      120

aucagcguga acagcaucga caucgaggug accaaggaga gccccaucac cagcaacagc      180

accaucauca accccaccaa cgagaccgac gacaccgccg gcaacaagcc caacuaccag      240

agaaagcccc uggugagcuu caaggaggac cccaccccca gcgacaaccc cuucagcaag      300

cuguacaagg agaccaucga gaccuucgac aacaacgagg aggagagcag cuacagcuac      360

gaggagauca acgaccagac caacgacaac aucaccgcca gacuggacag aaucgacgag      420

aagcugagcg agauccuggg caugcugcac acccuggugg uggccagcgc cggccccacc      480

agcgccagag acggcaucag agacgccaug aucggccuga gagaggagau gaucgagaag      540

aucagaaccg aggcccugau gaccaacgac agacuggagg ccauggccag acugagaaac      600

gaggagagcg agaagauggc caaggacacc agcgacgagg ugagccugaa ccccaccagc      660

gagaagcuga acaaccugcu ggagggcaac gacagcgaca acgaccugag ccuggaggac      720

uucuga                                                                 726


<210>  10643
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       HRSV(A2)__P03421.1__P

<400>  10643
auggagaagu ucgcccccga auuucacggc gaggacgcua acaauagagc caccaaauuc       60

cuggaaagca ucaaggggaa auuuacaucc ccuaaggauc cgaaaaagaa ggacucuauu      120

aucagcguga acuccauuga uaucgagguc acgaaagaau cucccauuac cagcaauucc      180

acaaucauca acccuaccaa ugagacagac gauaccgcgg gaaacaagcc caauuaccag      240

cggaaaccuc ucguuucuuu caaggaggac cccacaccua gcgauaaccc guuuuccaaa      300

cuguauaagg aaaccauuga gacguucgac aauaacgaag aggagagcuc uuacuccuau      360

gaagagauca augaucaaac caacgacaau auuacagcuc gccuugauag aaucgacgaa      420

aagcugagcg agauucucgg caugcugcau acccuugugg uggccucugc cgggcccaca      480

uccgcucggg auggaauccg cgacgccaug auuggccuga gagaagagau gaucgagaaa      540

auccggaccg aagcucucau gacgaacgac cgccuggagg ccauggcgag acugcggaau      600

gaagagagcg aaaagauggc caaagauaca ucugacgagg ucucccucaa cccuaccagc      660

gagaagcuga acaaucuucu ggaagggaac gauuccgaca augaucucuc ucuggaggac      720

uuuuga                                                                 726


<210>  10644
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       HRSV(A2)__P03421.1__P

<400>  10644
auggaaaaau ucgcaccaga auuucacgga gaagacgcaa acaacagagc aacaaaauuc       60

uuagaaucaa ucaaaggaaa auucacaagc ccaaaagacc caaaaaaaaa agacucaaua      120

auaagcguaa acucaauaga cauagaagua acaaaagaaa gcccaauaac aagcaacagc      180

acaauaauaa acccaacaaa cgaaacagau gacacagcug gaaauaaacc aaacuaccaa      240

agaaaacccc uagucagcuu caaagaagac cccacaccau cagacaaccc auucagcaaa      300

cuauauaaag aaacaauaga aacauuugac aacaacgaag aagaaucauc auacucauac      360

gaagaaauaa acgaccaaac aaacgacaac auaaccgcaa gauuagacag aauagaugaa      420

aaacuaucag aaauacuagg aaugcuacac acauuaguag uagcaagcgc aggaccaaca      480

ucagcaagag acggaauaag agacgcaaug auaggacuca gagaagaaau gauagaaaaa      540

auaagaacag aagcacuaau gacaaacgac agauuagaag caauggcaag acuaagaaau      600

gaagaaucgg aaaaaauggc aaaagacaca ucagacgaag uaagccuaaa cccaacauca      660

gaaaaauuaa auaaccuacu agaaggaaac gacagcgaca acgacuuauc acuagaagac      720

uucuaa                                                                 726


<210>  10645
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       HRSV(A2)__P03421.1__P

<400>  10645
auggaaaaau ucgcgcccga guuccacggc gaggacgcga acaaccgcgc gacaaaguuc       60

cuagaaucaa ucaagggcaa auucacgagc ccgaaagacc ccaagaaaaa ggacucaauc      120

auaagcguga acucgaucga caucgagguc acgaaagaga gcccgaucac aagcaacagc      180

accauaauaa acccgaccaa cgaaacagac gacaccgcgg gcaacaaacc gaacuaccaa      240

agaaaaccgc ucgugagcuu caaagaagac ccgaccccaa gcgacaaccc guucucaaaa      300

cuauacaagg aaacgaucga gaccuucgac aacaacgagg aagagagcuc guacucguac      360

gaggaaauaa acgaccaaac aaacgacaac auaaccgcac gccuagacag gaucgacgaa      420

aaacucucgg aaauacucgg gaugcuacac acgcucgugg ucgcgagcgc aggcccgacc      480

ucggccaggg acggcaucag ggacgcaaug auaggccugc gagaggaaau gaucgagaaa      540

auacgcaccg aagcacucau gaccaacgac agacucgaag ccauggccag gcucaggaac      600

gaagaauccg aaaagauggc gaaagacacc ucggacgagg ucucgcucaa ccccacgagc      660

gagaaacuga acaaccuacu ggaagggaac gacagcgaca acgaccuuuc ccucgaggac      720

uucuga                                                                 726


<210>  10646
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10646
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca      120

acagggcuac uaaauuccua gaaucaauaa agggcaaauu cacaucaccc aaagauccca      180

agaaaaaaga uaguaucaua ucugucaacu caauagauau agaaguaacc aaagaaagcc      240

cuauaacauc aaauucaacu auuaucaacc caacaaauga gacagaugau acugcaggga      300

acaagcccaa uuaucaaaga aaaccucuag uaaguuucaa agaagacccu acaccaagug      360

auaaucccuu uucuaaacua uacaaagaaa ccauagaaac auuugauaac aaugaagaag      420

aauccagcua uucauacgaa gaaauaaaug aucagacaaa cgauaauaua acagcaagau      480

uagauaggau ugaugaaaaa uuaagugaaa uacuaggaau gcuucacaca uuaguagugg      540

caagugcagg accuacaucu gcucgggaug guauaagaga ugccaugauu gguuuaagag      600

aagaaaugau agaaaaaauc agaacugaag cauuaaugac caaugacaga uuagaagcua      660

uggcaagacu caggaaugag gaaagugaaa agauggcaaa agacacauca gaugaagugu      720

cucucaaucc aacaucagag aaauugaaca accuauugga agggaaugau agugacaaug      780

aucuaucacu ugaagauuuc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10647
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10647
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgcgac caaguuccug gagagcauca aggggaaguu caccuccccg aaggacccca      180

agaagaagga cagcaucauc uccgugaaca gcaucgacau cgaggucacg aaggaguccc      240

ccaucaccag caacuccacc aucaucaacc ccaccaacga gacggacgac accgccggca      300

acaagccgaa cuaccagcgg aagccccucg ugagcuucaa ggaggacccc acccccuccg      360

acaacccguu cagcaagcug uacaaggaga ccaucgagac guucgacaac aacgaggagg      420

aguccagcua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

uggaccggau cgacgagaag cucagcgaga uccuggggau gcugcacacc cucguggucg      540

ccuccgccgg ccccacgagc gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg      600

aggagaugau cgagaagauc cggaccgagg cccugaugac caacgaccgc cucgaggcca      660

uggcgcggcu gcgcaacgag gaguccgaga agauggccaa ggacaccagc gacgaggugu      720

cccugaaccc cacgagcgag aagcucaaca accugcugga gggcaacgac agcgacaacg      780

accucucccu ggaggacuuc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10648
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10648
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgccac caaguuccuc gaguccauca agggcaaguu caccuccccc aaggacccca      180

agaagaagga cuccaucauc uccgucaacu ccaucgacau cgaggucacc aaggaguccc      240

ccaucaccuc caacuccacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagcgc aagccccucg ucuccuucaa ggaggacccc acccccuccg      360

acaaccccuu cuccaagcuc uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

aguccuccua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

ucgaccgcau cgacgagaag cucuccgaga uccucggcau gcuccacacc cucgucgucg      540

ccuccgccgg ccccaccucc gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg      600

aggagaugau cgagaagauc cgcaccgagg cccucaugac caacgaccgc cucgaggcca      660

uggcccgccu ccgcaacgag gaguccgaga agauggccaa ggacaccucc gacgaggucu      720

cccucaaccc caccuccgag aagcucaaca accuccucga gggcaacgac uccgacaacg      780

accucucccu cgaggacuuc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10649
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10649
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagcaac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuaua ucagugaaca guaucgauau ugaggucacu aaagaaagcc      240

caaucacguc caauucuacc auuaucaacc ccacaaauga gacugacgau accgccggaa      300

acaagccuaa uuaccagagg aaaccacucg uuucguucaa ggaggacccc acaccuucag      360

auaacccauu uagcaaacuu uauaaggaaa ccauagagac uuucgacaau aacgaagagg      420

agaguuccua cucuuaugaa gagaucaaug aucaaacaaa cgacaauauu accgcgcggc      480

uggaucgcau cgacgaaaag uugagcgaga uuuuagguau gcugcauacg cuagugguag      540

cuuccgccgg ccccacuuca gcacgagaug ggauccguga cgccaugaua ggacucagag      600

aagagaugau ugagaaaauc aggaccgaag cucugaugac aaacgaccgg cuugaggcaa      660

uggcccgccu gagaaaugaa gagagugaaa agauggcuaa agauacuagc gacgaggugu      720

cuuugaaccc uaccuccgag aagcucaaca aucugcugga aggcaacgau ucagacaaug      780

aucucagcuu agaggacuuu ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10650
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10650
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

acagagccac caaguuccug gagagcauca agggcaaguu caccagcccc aaggacccca      180

agaagaagga cagcaucauc agcgugaaca gcaucgacau cgaggugacc aaggagagcc      240

ccaucaccag caacagcacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagaga aagccccugg ugagcuucaa ggaggacccc acccccagcg      360

acaaccccuu cagcaagcug uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

agagcagcua cagcuacgag gagaucaacg accagaccaa cgacaacauc accgccagac      480

uggacagaau cgacgagaag cugagcgaga uccugggcau gcugcacacc cugguggugg      540

ccagcgccgg ccccaccagc gccagagacg gcaucagaga cgccaugauc ggccugagag      600

aggagaugau cgagaagauc agaaccgagg cccugaugac caacgacaga cuggaggcca      660

uggccagacu gagaaacgag gagagcgaga agauggccaa ggacaccagc gacgagguga      720

gccugaaccc caccagcgag aagcugaaca accugcugga gggcaacgac agcgacaacg      780

accugagccu ggaggacuuc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10651
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10651
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagccac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuauc agcgugaacu ccauugauau cgaggucacg aaagaaucuc      240

ccauuaccag caauuccaca aucaucaacc cuaccaauga gacagacgau accgcgggaa      300

acaagcccaa uuaccagcgg aaaccucucg uuucuuucaa ggaggacccc acaccuagcg      360

auaacccguu uuccaaacug uauaaggaaa ccauugagac guucgacaau aacgaagagg      420

agagcucuua cuccuaugaa gagaucaaug aucaaaccaa cgacaauauu acagcucgcc      480

uugauagaau cgacgaaaag cugagcgaga uucucggcau gcugcauacc cuuguggugg      540

ccucugccgg gcccacaucc gcucgggaug gaauccgcga cgccaugauu ggccugagag      600

aagagaugau cgagaaaauc cggaccgaag cucucaugac gaacgaccgc cuggaggcca      660

uggcgagacu gcggaaugaa gagagcgaaa agauggccaa agauacaucu gacgaggucu      720

cccucaaccc uaccagcgag aagcugaaca aucuucugga agggaacgau uccgacaaug      780

aucucucucu ggaggacuuu ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10652
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10652
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg caccagaauu ucacggagaa gacgcaaaca      120

acagagcaac aaaauucuua gaaucaauca aaggaaaauu cacaagccca aaagacccaa      180

aaaaaaaaga cucaauaaua agcguaaacu caauagacau agaaguaaca aaagaaagcc      240

caauaacaag caacagcaca auaauaaacc caacaaacga aacagaugac acagcuggaa      300

auaaaccaaa cuaccaaaga aaaccccuag ucagcuucaa agaagacccc acaccaucag      360

acaacccauu cagcaaacua uauaaagaaa caauagaaac auuugacaac aacgaagaag      420

aaucaucaua cucauacgaa gaaauaaacg accaaacaaa cgacaacaua accgcaagau      480

uagacagaau agaugaaaaa cuaucagaaa uacuaggaau gcuacacaca uuaguaguag      540

caagcgcagg accaacauca gcaagagacg gaauaagaga cgcaaugaua ggacucagag      600

aagaaaugau agaaaaaaua agaacagaag cacuaaugac aaacgacaga uuagaagcaa      660

uggcaagacu aagaaaugaa gaaucggaaa aaauggcaaa agacacauca gacgaaguaa      720

gccuaaaccc aacaucagaa aaauuaaaua accuacuaga aggaaacgac agcgacaacg      780

acuuaucacu agaagacuuc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10653
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10653
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca      120

accgcgcgac aaaguuccua gaaucaauca agggcaaauu cacgagcccg aaagacccca      180

agaaaaagga cucaaucaua agcgugaacu cgaucgacau cgaggucacg aaagagagcc      240

cgaucacaag caacagcacc auaauaaacc cgaccaacga aacagacgac accgcgggca      300

acaaaccgaa cuaccaaaga aaaccgcucg ugagcuucaa agaagacccg accccaagcg      360

acaacccguu cucaaaacua uacaaggaaa cgaucgagac cuucgacaac aacgaggaag      420

agagcucgua cucguacgag gaaauaaacg accaaacaaa cgacaacaua accgcacgcc      480

uagacaggau cgacgaaaaa cucucggaaa uacucgggau gcuacacacg cucguggucg      540

cgagcgcagg cccgaccucg gccagggacg gcaucaggga cgcaaugaua ggccugcgag      600

aggaaaugau cgagaaaaua cgcaccgaag cacucaugac caacgacaga cucgaagcca      660

uggccaggcu caggaacgaa gaauccgaaa agauggcgaa agacaccucg gacgaggucu      720

cgcucaaccc cacgagcgag aaacugaaca accuacugga agggaacgac agcgacaacg      780

accuuucccu cgaggacuuc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  10654
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10654
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaguuugc uccugaauuc      120

cauggagaag augcaaacaa cagggcuacu aaauuccuag aaucaauaaa gggcaaauuc      180

acaucaccca aagaucccaa gaaaaaagau aguaucauau cugucaacuc aauagauaua      240

gaaguaacca aagaaagccc uauaacauca aauucaacua uuaucaaccc aacaaaugag      300

acagaugaua cugcagggaa caagcccaau uaucaaagaa aaccucuagu aaguuucaaa      360

gaagacccua caccaaguga uaaucccuuu ucuaaacuau acaaagaaac cauagaaaca      420

uuugauaaca augaagaaga auccagcuau ucauacgaag aaauaaauga ucagacaaac      480

gauaauauaa cagcaagauu agauaggauu gaugaaaaau uaagugaaau acuaggaaug      540

cuucacacau uaguaguggc aagugcagga ccuacaucug cucgggaugg uauaagagau      600

gccaugauug guuuaagaga agaaaugaua gaaaaaauca gaacugaagc auuaaugacc      660

aaugacagau uagaagcuau ggcaagacuc aggaaugagg aaagugaaaa gauggcaaaa      720

gacacaucag augaaguguc ucucaaucca acaucagaga aauugaacaa ccuauuggaa      780

gggaaugaua gugacaauga ucuaucacuu gaagauuucu gaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10655
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10655
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgcgacc aaguuccugg agagcaucaa ggggaaguuc      180

accuccccga aggaccccaa gaagaaggac agcaucaucu ccgugaacag caucgacauc      240

gaggucacga aggagucccc caucaccagc aacuccacca ucaucaaccc caccaacgag      300

acggacgaca ccgccggcaa caagccgaac uaccagcgga agccccucgu gagcuucaag      360

gaggacccca cccccuccga caacccguuc agcaagcugu acaaggagac caucgagacg      420

uucgacaaca acgaggagga guccagcuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu ggaccggauc gacgagaagc ucagcgagau ccuggggaug      540

cugcacaccc ucguggucgc cuccgccggc cccacgagcg cgcgcgacgg gauccgggac      600

gccaugaucg gccugcgcga ggagaugauc gagaagaucc ggaccgaggc ccugaugacc      660

aacgaccgcc ucgaggccau ggcgcggcug cgcaacgagg aguccgagaa gauggccaag      720

gacaccagcg acgagguguc ccugaacccc acgagcgaga agcucaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccucucccug gaggacuucu gaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10656
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10656
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgccacc aaguuccucg aguccaucaa gggcaaguuc      180

accuccccca aggaccccaa gaagaaggac uccaucaucu ccgucaacuc caucgacauc      240

gaggucacca aggagucccc caucaccucc aacuccacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagcgca agccccucgu cuccuucaag      360

gaggacccca cccccuccga caaccccuuc uccaagcucu acaaggagac caucgagacc      420

uucgacaaca acgaggagga guccuccuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu cgaccgcauc gacgagaagc ucuccgagau ccucggcaug      540

cuccacaccc ucgucgucgc cuccgccggc cccaccuccg cccgcgacgg cauccgcgac      600

gccaugaucg gccuccgcga ggagaugauc gagaagaucc gcaccgaggc ccucaugacc      660

aacgaccgcc ucgaggccau ggcccgccuc cgcaacgagg aguccgagaa gauggccaag      720

gacaccuccg acgaggucuc ccucaacccc accuccgaga agcucaacaa ccuccucgag      780

ggcaacgacu ccgacaacga ccucucccuc gaggacuucu gaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10657
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10657
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagcaacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauau cagugaacag uaucgauauu      240

gaggucacua aagaaagccc aaucacgucc aauucuacca uuaucaaccc cacaaaugag      300

acugacgaua ccgccggaaa caagccuaau uaccagagga aaccacucgu uucguucaag      360

gaggacccca caccuucaga uaacccauuu agcaaacuuu auaaggaaac cauagagacu      420

uucgacaaua acgaagagga gaguuccuac ucuuaugaag agaucaauga ucaaacaaac      480

gacaauauua ccgcgcggcu ggaucgcauc gacgaaaagu ugagcgagau uuuagguaug      540

cugcauacgc uagugguagc uuccgccggc cccacuucag cacgagaugg gauccgugac      600

gccaugauag gacucagaga agagaugauu gagaaaauca ggaccgaagc ucugaugaca      660

aacgaccggc uugaggcaau ggcccgccug agaaaugaag agagugaaaa gauggcuaaa      720

gauacuagcg acgagguguc uuugaacccu accuccgaga agcucaacaa ucugcuggaa      780

ggcaacgauu cagacaauga ucucagcuua gaggacuuuu gaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10658
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10658
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa cagagccacc aaguuccugg agagcaucaa gggcaaguuc      180

accagcccca aggaccccaa gaagaaggac agcaucauca gcgugaacag caucgacauc      240

gaggugacca aggagagccc caucaccagc aacagcacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagagaa agccccuggu gagcuucaag      360

gaggacccca cccccagcga caaccccuuc agcaagcugu acaaggagac caucgagacc      420

uucgacaaca acgaggagga gagcagcuac agcuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgccagacu ggacagaauc gacgagaagc ugagcgagau ccugggcaug      540

cugcacaccc uggugguggc cagcgccggc cccaccagcg ccagagacgg caucagagac      600

gccaugaucg gccugagaga ggagaugauc gagaagauca gaaccgaggc ccugaugacc      660

aacgacagac uggaggccau ggccagacug agaaacgagg agagcgagaa gauggccaag      720

gacaccagcg acgaggugag ccugaacccc accagcgaga agcugaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccugagccug gaggacuucu gaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10659
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10659
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagccacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauca gcgugaacuc cauugauauc      240

gaggucacga aagaaucucc cauuaccagc aauuccacaa ucaucaaccc uaccaaugag      300

acagacgaua ccgcgggaaa caagcccaau uaccagcgga aaccucucgu uucuuucaag      360

gaggacccca caccuagcga uaacccguuu uccaaacugu auaaggaaac cauugagacg      420

uucgacaaua acgaagagga gagcucuuac uccuaugaag agaucaauga ucaaaccaac      480

gacaauauua cagcucgccu ugauagaauc gacgaaaagc ugagcgagau ucucggcaug      540

cugcauaccc uugugguggc cucugccggg cccacauccg cucgggaugg aauccgcgac      600

gccaugauug gccugagaga agagaugauc gagaaaaucc ggaccgaagc ucucaugacg      660

aacgaccgcc uggaggccau ggcgagacug cggaaugaag agagcgaaaa gauggccaaa      720

gauacaucug acgaggucuc ccucaacccu accagcgaga agcugaacaa ucuucuggaa      780

gggaacgauu ccgacaauga ucucucucug gaggacuuuu gaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10660
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10660
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc accagaauuu      120

cacggagaag acgcaaacaa cagagcaaca aaauucuuag aaucaaucaa aggaaaauuc      180

acaagcccaa aagacccaaa aaaaaaagac ucaauaauaa gcguaaacuc aauagacaua      240

gaaguaacaa aagaaagccc aauaacaagc aacagcacaa uaauaaaccc aacaaacgaa      300

acagaugaca cagcuggaaa uaaaccaaac uaccaaagaa aaccccuagu cagcuucaaa      360

gaagacccca caccaucaga caacccauuc agcaaacuau auaaagaaac aauagaaaca      420

uuugacaaca acgaagaaga aucaucauac ucauacgaag aaauaaacga ccaaacaaac      480

gacaacauaa ccgcaagauu agacagaaua gaugaaaaac uaucagaaau acuaggaaug      540

cuacacacau uaguaguagc aagcgcagga ccaacaucag caagagacgg aauaagagac      600

gcaaugauag gacucagaga agaaaugaua gaaaaaauaa gaacagaagc acuaaugaca      660

aacgacagau uagaagcaau ggcaagacua agaaaugaag aaucggaaaa aauggcaaaa      720

gacacaucag acgaaguaag ccuaaaccca acaucagaaa aauuaaauaa ccuacuagaa      780

ggaaacgaca gcgacaacga cuuaucacua gaagacuucu aaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10661
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10661
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc gcccgaguuc      120

cacggcgagg acgcgaacaa ccgcgcgaca aaguuccuag aaucaaucaa gggcaaauuc      180

acgagcccga aagaccccaa gaaaaaggac ucaaucauaa gcgugaacuc gaucgacauc      240

gaggucacga aagagagccc gaucacaagc aacagcacca uaauaaaccc gaccaacgaa      300

acagacgaca ccgcgggcaa caaaccgaac uaccaaagaa aaccgcucgu gagcuucaaa      360

gaagacccga ccccaagcga caacccguuc ucaaaacuau acaaggaaac gaucgagacc      420

uucgacaaca acgaggaaga gagcucguac ucguacgagg aaauaaacga ccaaacaaac      480

gacaacauaa ccgcacgccu agacaggauc gacgaaaaac ucucggaaau acucgggaug      540

cuacacacgc ucguggucgc gagcgcaggc ccgaccucgg ccagggacgg caucagggac      600

gcaaugauag gccugcgaga ggaaaugauc gagaaaauac gcaccgaagc acucaugacc      660

aacgacagac ucgaagccau ggccaggcuc aggaacgaag aauccgaaaa gauggcgaaa      720

gacaccucgg acgaggucuc gcucaacccc acgagcgaga aacugaacaa ccuacuggaa      780

gggaacgaca gcgacaacga ccuuucccuc gaggacuucu gaggacuagu cccuguuccc      840

agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  10662
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10662
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaguuugcuc cugaauucca uggagaagau gcaaacaaca gggcuacuaa auuccuagaa      240

ucaauaaagg gcaaauucac aucacccaaa gaucccaaga aaaaagauag uaucauaucu      300

gucaacucaa uagauauaga aguaaccaaa gaaagcccua uaacaucaaa uucaacuauu      360

aucaacccaa caaaugagac agaugauacu gcagggaaca agcccaauua ucaaagaaaa      420

ccucuaguaa guuucaaaga agacccuaca ccaagugaua aucccuuuuc uaaacuauac      480

aaagaaacca uagaaacauu ugauaacaau gaagaagaau ccagcuauuc auacgaagaa      540

auaaaugauc agacaaacga uaauauaaca gcaagauuag auaggauuga ugaaaaauua      600

agugaaauac uaggaaugcu ucacacauua guaguggcaa gugcaggacc uacaucugcu      660

cgggauggua uaagagaugc caugauuggu uuaagagaag aaaugauaga aaaaaucaga      720

acugaagcau uaaugaccaa ugacagauua gaagcuaugg caagacucag gaaugaggaa      780

agugaaaaga uggcaaaaga cacaucagau gaagugucuc ucaauccaac aucagagaaa      840

uugaacaacc uauuggaagg gaaugauagu gacaaugauc uaucacuuga agauuucuga      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10663
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10663
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgcgaccaa guuccuggag      240

agcaucaagg ggaaguucac cuccccgaag gaccccaaga agaaggacag caucaucucc      300

gugaacagca ucgacaucga ggucacgaag gaguccccca ucaccagcaa cuccaccauc      360

aucaacccca ccaacgagac ggacgacacc gccggcaaca agccgaacua ccagcggaag      420

ccccucguga gcuucaagga ggaccccacc cccuccgaca acccguucag caagcuguac      480

aaggagacca ucgagacguu cgacaacaac gaggaggagu ccagcuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccugg accggaucga cgagaagcuc      600

agcgagaucc uggggaugcu gcacacccuc guggucgccu ccgccggccc cacgagcgcg      660

cgcgacggga uccgggacgc caugaucggc cugcgcgagg agaugaucga gaagauccgg      720

accgaggccc ugaugaccaa cgaccgccuc gaggccaugg cgcggcugcg caacgaggag      780

uccgagaaga uggccaagga caccagcgac gagguguccc ugaaccccac gagcgagaag      840

cucaacaacc ugcuggaggg caacgacagc gacaacgacc ucucccugga ggacuucuga      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10664
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10664
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgccaccaa guuccucgag      240

uccaucaagg gcaaguucac cucccccaag gaccccaaga agaaggacuc caucaucucc      300

gucaacucca ucgacaucga ggucaccaag gaguccccca ucaccuccaa cuccaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagcgcaag      420

ccccucgucu ccuucaagga ggaccccacc cccuccgaca accccuucuc caagcucuac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggagu ccuccuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccucg accgcaucga cgagaagcuc      600

uccgagaucc ucggcaugcu ccacacccuc gucgucgccu ccgccggccc caccuccgcc      660

cgcgacggca uccgcgacgc caugaucggc cuccgcgagg agaugaucga gaagauccgc      720

accgaggccc ucaugaccaa cgaccgccuc gaggccaugg cccgccuccg caacgaggag      780

uccgagaaga uggccaagga caccuccgac gaggucuccc ucaaccccac cuccgagaag      840

cucaacaacc uccucgaggg caacgacucc gacaacgacc ucucccucga ggacuucuga      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10665
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10665
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagcaaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuauauca      300

gugaacagua ucgauauuga ggucacuaaa gaaagcccaa ucacguccaa uucuaccauu      360

aucaacccca caaaugagac ugacgauacc gccggaaaca agccuaauua ccagaggaaa      420

ccacucguuu cguucaagga ggaccccaca ccuucagaua acccauuuag caaacuuuau      480

aaggaaacca uagagacuuu cgacaauaac gaagaggaga guuccuacuc uuaugaagag      540

aucaaugauc aaacaaacga caauauuacc gcgcggcugg aucgcaucga cgaaaaguug      600

agcgagauuu uagguaugcu gcauacgcua gugguagcuu ccgccggccc cacuucagca      660

cgagauggga uccgugacgc caugauagga cucagagaag agaugauuga gaaaaucagg      720

accgaagcuc ugaugacaaa cgaccggcuu gaggcaaugg cccgccugag aaaugaagag      780

agugaaaaga uggcuaaaga uacuagcgac gaggugucuu ugaacccuac cuccgagaag      840

cucaacaauc ugcuggaagg caacgauuca gacaaugauc ucagcuuaga ggacuuuuga      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10666
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10666
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaaca gagccaccaa guuccuggag      240

agcaucaagg gcaaguucac cagccccaag gaccccaaga agaaggacag caucaucagc      300

gugaacagca ucgacaucga ggugaccaag gagagcccca ucaccagcaa cagcaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagagaaag      420

ccccugguga gcuucaagga ggaccccacc cccagcgaca accccuucag caagcuguac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggaga gcagcuacag cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gccagacugg acagaaucga cgagaagcug      600

agcgagaucc ugggcaugcu gcacacccug gugguggcca gcgccggccc caccagcgcc      660

agagacggca ucagagacgc caugaucggc cugagagagg agaugaucga gaagaucaga      720

accgaggccc ugaugaccaa cgacagacug gaggccaugg ccagacugag aaacgaggag      780

agcgagaaga uggccaagga caccagcgac gaggugagcc ugaaccccac cagcgagaag      840

cugaacaacc ugcuggaggg caacgacagc gacaacgacc ugagccugga ggacuucuga      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10667
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10667
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagccaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuaucagc      300

gugaacucca uugauaucga ggucacgaaa gaaucuccca uuaccagcaa uuccacaauc      360

aucaacccua ccaaugagac agacgauacc gcgggaaaca agcccaauua ccagcggaaa      420

ccucucguuu cuuucaagga ggaccccaca ccuagcgaua acccguuuuc caaacuguau      480

aaggaaacca uugagacguu cgacaauaac gaagaggaga gcucuuacuc cuaugaagag      540

aucaaugauc aaaccaacga caauauuaca gcucgccuug auagaaucga cgaaaagcug      600

agcgagauuc ucggcaugcu gcauacccuu gugguggccu cugccgggcc cacauccgcu      660

cgggauggaa uccgcgacgc caugauuggc cugagagaag agaugaucga gaaaauccgg      720

accgaagcuc ucaugacgaa cgaccgccug gaggccaugg cgagacugcg gaaugaagag      780

agcgaaaaga uggccaaaga uacaucugac gaggucuccc ucaacccuac cagcgagaag      840

cugaacaauc uucuggaagg gaacgauucc gacaaugauc ucucucugga ggacuuuuga      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10668
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10668
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcac cagaauuuca cggagaagac gcaaacaaca gagcaacaaa auucuuagaa      240

ucaaucaaag gaaaauucac aagcccaaaa gacccaaaaa aaaaagacuc aauaauaagc      300

guaaacucaa uagacauaga aguaacaaaa gaaagcccaa uaacaagcaa cagcacaaua      360

auaaacccaa caaacgaaac agaugacaca gcuggaaaua aaccaaacua ccaaagaaaa      420

ccccuaguca gcuucaaaga agaccccaca ccaucagaca acccauucag caaacuauau      480

aaagaaacaa uagaaacauu ugacaacaac gaagaagaau caucauacuc auacgaagaa      540

auaaacgacc aaacaaacga caacauaacc gcaagauuag acagaauaga ugaaaaacua      600

ucagaaauac uaggaaugcu acacacauua guaguagcaa gcgcaggacc aacaucagca      660

agagacggaa uaagagacgc aaugauagga cucagagaag aaaugauaga aaaaauaaga      720

acagaagcac uaaugacaaa cgacagauua gaagcaaugg caagacuaag aaaugaagaa      780

ucggaaaaaa uggcaaaaga cacaucagac gaaguaagcc uaaacccaac aucagaaaaa      840

uuaaauaacc uacuagaagg aaacgacagc gacaacgacu uaucacuaga agacuucuaa      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10669
<211>  1099
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10669
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcgc ccgaguucca cggcgaggac gcgaacaacc gcgcgacaaa guuccuagaa      240

ucaaucaagg gcaaauucac gagcccgaaa gaccccaaga aaaaggacuc aaucauaagc      300

gugaacucga ucgacaucga ggucacgaaa gagagcccga ucacaagcaa cagcaccaua      360

auaaacccga ccaacgaaac agacgacacc gcgggcaaca aaccgaacua ccaaagaaaa      420

ccgcucguga gcuucaaaga agacccgacc ccaagcgaca acccguucuc aaaacuauac      480

aaggaaacga ucgagaccuu cgacaacaac gaggaagaga gcucguacuc guacgaggaa      540

auaaacgacc aaacaaacga caacauaacc gcacgccuag acaggaucga cgaaaaacuc      600

ucggaaauac ucgggaugcu acacacgcuc guggucgcga gcgcaggccc gaccucggcc      660

agggacggca ucagggacgc aaugauaggc cugcgagagg aaaugaucga gaaaauacgc      720

accgaagcac ucaugaccaa cgacagacuc gaagccaugg ccaggcucag gaacgaagaa      780

uccgaaaaga uggcgaaaga caccucggac gaggucucgc ucaaccccac gagcgagaaa      840

cugaacaacc uacuggaagg gaacgacagc gacaacgacc uuucccucga ggacuucuga      900

ggacuagucc cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu      960

cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1080

uuucagagcc accagaauu                                                  1099


<210>  10670
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10670
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aguuugcucc ugaauuccau ggagaagaug caaacaacag ggcuacuaaa      180

uuccuagaau caauaaaggg caaauucaca ucacccaaag aucccaagaa aaaagauagu      240

aucauaucug ucaacucaau agauauagaa guaaccaaag aaagcccuau aacaucaaau      300

ucaacuauua ucaacccaac aaaugagaca gaugauacug cagggaacaa gcccaauuau      360

caaagaaaac cucuaguaag uuucaaagaa gacccuacac caagugauaa ucccuuuucu      420

aaacuauaca aagaaaccau agaaacauuu gauaacaaug aagaagaauc cagcuauuca      480

uacgaagaaa uaaaugauca gacaaacgau aauauaacag caagauuaga uaggauugau      540

gaaaaauuaa gugaaauacu aggaaugcuu cacacauuag uaguggcaag ugcaggaccu      600

acaucugcuc gggaugguau aagagaugcc augauugguu uaagagaaga aaugauagaa      660

aaaaucagaa cugaagcauu aaugaccaau gacagauuag aagcuauggc aagacucagg      720

aaugaggaaa gugaaaagau ggcaaaagac acaucagaug aagugucucu caauccaaca      780

ucagagaaau ugaacaaccu auuggaaggg aaugauagug acaaugaucu aucacuugaa      840

gauuucugag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10671
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10671
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgcgaccaag      180

uuccuggaga gcaucaaggg gaaguucacc uccccgaagg accccaagaa gaaggacagc      240

aucaucuccg ugaacagcau cgacaucgag gucacgaagg agucccccau caccagcaac      300

uccaccauca ucaaccccac caacgagacg gacgacaccg ccggcaacaa gccgaacuac      360

cagcggaagc cccucgugag cuucaaggag gaccccaccc ccuccgacaa cccguucagc      420

aagcuguaca aggagaccau cgagacguuc gacaacaacg aggaggaguc cagcuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccugga ccggaucgac      540

gagaagcuca gcgagauccu ggggaugcug cacacccucg uggucgccuc cgccggcccc      600

acgagcgcgc gcgacgggau ccgggacgcc augaucggcc ugcgcgagga gaugaucgag      660

aagauccgga ccgaggcccu gaugaccaac gaccgccucg aggccauggc gcggcugcgc      720

aacgaggagu ccgagaagau ggccaaggac accagcgacg aggugucccu gaaccccacg      780

agcgagaagc ucaacaaccu gcuggagggc aacgacagcg acaacgaccu cucccuggag      840

gacuucugag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10672
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10672
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgccaccaag      180

uuccucgagu ccaucaaggg caaguucacc ucccccaagg accccaagaa gaaggacucc      240

aucaucuccg ucaacuccau cgacaucgag gucaccaagg agucccccau caccuccaac      300

uccaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagcgcaagc cccucgucuc cuucaaggag gaccccaccc ccuccgacaa ccccuucucc      420

aagcucuaca aggagaccau cgagaccuuc gacaacaacg aggaggaguc cuccuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccucga ccgcaucgac      540

gagaagcucu ccgagauccu cggcaugcuc cacacccucg ucgucgccuc cgccggcccc      600

accuccgccc gcgacggcau ccgcgacgcc augaucggcc uccgcgagga gaugaucgag      660

aagauccgca ccgaggcccu caugaccaac gaccgccucg aggccauggc ccgccuccgc      720

aacgaggagu ccgagaagau ggccaaggac accuccgacg aggucucccu caaccccacc      780

uccgagaagc ucaacaaccu ccucgagggc aacgacuccg acaacgaccu cucccucgag      840

gacuucugag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10673
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10673
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agcaaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuauaucag ugaacaguau cgauauugag gucacuaaag aaagcccaau cacguccaau      300

ucuaccauua ucaaccccac aaaugagacu gacgauaccg ccggaaacaa gccuaauuac      360

cagaggaaac cacucguuuc guucaaggag gaccccacac cuucagauaa cccauuuagc      420

aaacuuuaua aggaaaccau agagacuuuc gacaauaacg aagaggagag uuccuacucu      480

uaugaagaga ucaaugauca aacaaacgac aauauuaccg cgcggcugga ucgcaucgac      540

gaaaaguuga gcgagauuuu agguaugcug cauacgcuag ugguagcuuc cgccggcccc      600

acuucagcac gagaugggau ccgugacgcc augauaggac ucagagaaga gaugauugag      660

aaaaucagga ccgaagcucu gaugacaaac gaccggcuug aggcaauggc ccgccugaga      720

aaugaagaga gugaaaagau ggcuaaagau acuagcgacg aggugucuuu gaacccuacc      780

uccgagaagc ucaacaaucu gcuggaaggc aacgauucag acaaugaucu cagcuuagag      840

gacuuuugag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10674
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10674
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaacag agccaccaag      180

uuccuggaga gcaucaaggg caaguucacc agccccaagg accccaagaa gaaggacagc      240

aucaucagcg ugaacagcau cgacaucgag gugaccaagg agagccccau caccagcaac      300

agcaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagagaaagc cccuggugag cuucaaggag gaccccaccc ccagcgacaa ccccuucagc      420

aagcuguaca aggagaccau cgagaccuuc gacaacaacg aggaggagag cagcuacagc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg ccagacugga cagaaucgac      540

gagaagcuga gcgagauccu gggcaugcug cacacccugg ugguggccag cgccggcccc      600

accagcgcca gagacggcau cagagacgcc augaucggcc ugagagagga gaugaucgag      660

aagaucagaa ccgaggcccu gaugaccaac gacagacugg aggccauggc cagacugaga      720

aacgaggaga gcgagaagau ggccaaggac accagcgacg aggugagccu gaaccccacc      780

agcgagaagc ugaacaaccu gcuggagggc aacgacagcg acaacgaccu gagccuggag      840

gacuucugag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10675
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10675
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agccaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuaucagcg ugaacuccau ugauaucgag gucacgaaag aaucucccau uaccagcaau      300

uccacaauca ucaacccuac caaugagaca gacgauaccg cgggaaacaa gcccaauuac      360

cagcggaaac cucucguuuc uuucaaggag gaccccacac cuagcgauaa cccguuuucc      420

aaacuguaua aggaaaccau ugagacguuc gacaauaacg aagaggagag cucuuacucc      480

uaugaagaga ucaaugauca aaccaacgac aauauuacag cucgccuuga uagaaucgac      540

gaaaagcuga gcgagauucu cggcaugcug cauacccuug ugguggccuc ugccgggccc      600

acauccgcuc gggauggaau ccgcgacgcc augauuggcc ugagagaaga gaugaucgag      660

aaaauccgga ccgaagcucu caugacgaac gaccgccugg aggccauggc gagacugcgg      720

aaugaagaga gcgaaaagau ggccaaagau acaucugacg aggucucccu caacccuacc      780

agcgagaagc ugaacaaucu ucuggaaggg aacgauuccg acaaugaucu cucucuggag      840

gacuuuugag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10676
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10676
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcacc agaauuucac ggagaagacg caaacaacag agcaacaaaa      180

uucuuagaau caaucaaagg aaaauucaca agcccaaaag acccaaaaaa aaaagacuca      240

auaauaagcg uaaacucaau agacauagaa guaacaaaag aaagcccaau aacaagcaac      300

agcacaauaa uaaacccaac aaacgaaaca gaugacacag cuggaaauaa accaaacuac      360

caaagaaaac cccuagucag cuucaaagaa gaccccacac caucagacaa cccauucagc      420

aaacuauaua aagaaacaau agaaacauuu gacaacaacg aagaagaauc aucauacuca      480

uacgaagaaa uaaacgacca aacaaacgac aacauaaccg caagauuaga cagaauagau      540

gaaaaacuau cagaaauacu aggaaugcua cacacauuag uaguagcaag cgcaggacca      600

acaucagcaa gagacggaau aagagacgca augauaggac ucagagaaga aaugauagaa      660

aaaauaagaa cagaagcacu aaugacaaac gacagauuag aagcaauggc aagacuaaga      720

aaugaagaau cggaaaaaau ggcaaaagac acaucagacg aaguaagccu aaacccaaca      780

ucagaaaaau uaaauaaccu acuagaagga aacgacagcg acaacgacuu aucacuagaa      840

gacuucuaag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10677
<211>  1048
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10677
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcgcc cgaguuccac ggcgaggacg cgaacaaccg cgcgacaaag      180

uuccuagaau caaucaaggg caaauucacg agcccgaaag accccaagaa aaaggacuca      240

aucauaagcg ugaacucgau cgacaucgag gucacgaaag agagcccgau cacaagcaac      300

agcaccauaa uaaacccgac caacgaaaca gacgacaccg cgggcaacaa accgaacuac      360

caaagaaaac cgcucgugag cuucaaagaa gacccgaccc caagcgacaa cccguucuca      420

aaacuauaca aggaaacgau cgagaccuuc gacaacaacg aggaagagag cucguacucg      480

uacgaggaaa uaaacgacca aacaaacgac aacauaaccg cacgccuaga caggaucgac      540

gaaaaacucu cggaaauacu cgggaugcua cacacgcucg uggucgcgag cgcaggcccg      600

accucggcca gggacggcau cagggacgca augauaggcc ugcgagagga aaugaucgag      660

aaaauacgca ccgaagcacu caugaccaac gacagacucg aagccauggc caggcucagg      720

aacgaagaau ccgaaaagau ggcgaaagac accucggacg aggucucgcu caaccccacg      780

agcgagaaac ugaacaaccu acuggaaggg aacgacagcg acaacgaccu uucccucgag      840

gacuucugag gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa      900

auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1020

aaaggcucuu uucagagcca ccagaauu                                        1048


<210>  10678
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10678
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaguu ugcuccugaa uuccauggag aagaugcaaa caacagggcu      120

acuaaauucc uagaaucaau aaagggcaaa uucacaucac ccaaagaucc caagaaaaaa      180

gauaguauca uaucugucaa cucaauagau auagaaguaa ccaaagaaag cccuauaaca      240

ucaaauucaa cuauuaucaa cccaacaaau gagacagaug auacugcagg gaacaagccc      300

aauuaucaaa gaaaaccucu aguaaguuuc aaagaagacc cuacaccaag ugauaauccc      360

uuuucuaaac uauacaaaga aaccauagaa acauuugaua acaaugaaga agaauccagc      420

uauucauacg aagaaauaaa ugaucagaca aacgauaaua uaacagcaag auuagauagg      480

auugaugaaa aauuaaguga aauacuagga augcuucaca cauuaguagu ggcaagugca      540

ggaccuacau cugcucggga ugguauaaga gaugccauga uugguuuaag agaagaaaug      600

auagaaaaaa ucagaacuga agcauuaaug accaaugaca gauuagaagc uauggcaaga      660

cucaggaaug aggaaaguga aaagauggca aaagacacau cagaugaagu gucucucaau      720

ccaacaucag agaaauugaa caaccuauug gaagggaaug auagugacaa ugaucuauca      780

cuugaagauu ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10679
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10679
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcg      120

accaaguucc uggagagcau caaggggaag uucaccuccc cgaaggaccc caagaagaag      180

gacagcauca ucuccgugaa cagcaucgac aucgagguca cgaaggaguc ccccaucacc      240

agcaacucca ccaucaucaa ccccaccaac gagacggacg acaccgccgg caacaagccg      300

aacuaccagc ggaagccccu cgugagcuuc aaggaggacc ccacccccuc cgacaacccg      360

uucagcaagc uguacaagga gaccaucgag acguucgaca acaacgagga ggaguccagc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccuggaccgg      480

aucgacgaga agcucagcga gauccugggg augcugcaca cccucguggu cgccuccgcc      540

ggccccacga gcgcgcgcga cgggauccgg gacgccauga ucggccugcg cgaggagaug      600

aucgagaaga uccggaccga ggcccugaug accaacgacc gccucgaggc cauggcgcgg      660

cugcgcaacg aggaguccga gaagauggcc aaggacacca gcgacgaggu gucccugaac      720

cccacgagcg agaagcucaa caaccugcug gagggcaacg acagcgacaa cgaccucucc      780

cuggaggacu ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10680
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10680
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcc      120

accaaguucc ucgaguccau caagggcaag uucaccuccc ccaaggaccc caagaagaag      180

gacuccauca ucuccgucaa cuccaucgac aucgagguca ccaaggaguc ccccaucacc      240

uccaacucca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccagc gcaagccccu cgucuccuuc aaggaggacc ccacccccuc cgacaacccc      360

uucuccaagc ucuacaagga gaccaucgag accuucgaca acaacgagga ggaguccucc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccucgaccgc      480

aucgacgaga agcucuccga gauccucggc augcuccaca cccucgucgu cgccuccgcc      540

ggccccaccu ccgcccgcga cggcauccgc gacgccauga ucggccuccg cgaggagaug      600

aucgagaaga uccgcaccga ggcccucaug accaacgacc gccucgaggc cauggcccgc      660

cuccgcaacg aggaguccga gaagauggcc aaggacaccu ccgacgaggu cucccucaac      720

cccaccuccg agaagcucaa caaccuccuc gagggcaacg acuccgacaa cgaccucucc      780

cucgaggacu ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10681
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10681
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagca      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua uaucagugaa caguaucgau auugagguca cuaaagaaag cccaaucacg      240

uccaauucua ccauuaucaa ccccacaaau gagacugacg auaccgccgg aaacaagccu      300

aauuaccaga ggaaaccacu cguuucguuc aaggaggacc ccacaccuuc agauaaccca      360

uuuagcaaac uuuauaagga aaccauagag acuuucgaca auaacgaaga ggagaguucc      420

uacucuuaug aagagaucaa ugaucaaaca aacgacaaua uuaccgcgcg gcuggaucgc      480

aucgacgaaa aguugagcga gauuuuaggu augcugcaua cgcuaguggu agcuuccgcc      540

ggccccacuu cagcacgaga ugggauccgu gacgccauga uaggacucag agaagagaug      600

auugagaaaa ucaggaccga agcucugaug acaaacgacc ggcuugaggc aauggcccgc      660

cugagaaaug aagagaguga aaagauggcu aaagauacua gcgacgaggu gucuuugaac      720

ccuaccuccg agaagcucaa caaucugcug gaaggcaacg auucagacaa ugaucucagc      780

uuagaggacu uuugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10682
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10682
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caacagagcc      120

accaaguucc uggagagcau caagggcaag uucaccagcc ccaaggaccc caagaagaag      180

gacagcauca ucagcgugaa cagcaucgac aucgagguga ccaaggagag ccccaucacc      240

agcaacagca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccaga gaaagccccu ggugagcuuc aaggaggacc ccacccccag cgacaacccc      360

uucagcaagc uguacaagga gaccaucgag accuucgaca acaacgagga ggagagcagc      420

uacagcuacg aggagaucaa cgaccagacc aacgacaaca ucaccgccag acuggacaga      480

aucgacgaga agcugagcga gauccugggc augcugcaca cccugguggu ggccagcgcc      540

ggccccacca gcgccagaga cggcaucaga gacgccauga ucggccugag agaggagaug      600

aucgagaaga ucagaaccga ggcccugaug accaacgaca gacuggaggc cauggccaga      660

cugagaaacg aggagagcga gaagauggcc aaggacacca gcgacgaggu gagccugaac      720

cccaccagcg agaagcugaa caaccugcug gagggcaacg acagcgacaa cgaccugagc      780

cuggaggacu ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10683
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10683
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagcc      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua ucagcgugaa cuccauugau aucgagguca cgaaagaauc ucccauuacc      240

agcaauucca caaucaucaa cccuaccaau gagacagacg auaccgcggg aaacaagccc      300

aauuaccagc ggaaaccucu cguuucuuuc aaggaggacc ccacaccuag cgauaacccg      360

uuuuccaaac uguauaagga aaccauugag acguucgaca auaacgaaga ggagagcucu      420

uacuccuaug aagagaucaa ugaucaaacc aacgacaaua uuacagcucg ccuugauaga      480

aucgacgaaa agcugagcga gauucucggc augcugcaua cccuuguggu ggccucugcc      540

gggcccacau ccgcucggga uggaauccgc gacgccauga uuggccugag agaagagaug      600

aucgagaaaa uccggaccga agcucucaug acgaacgacc gccuggaggc cauggcgaga      660

cugcggaaug aagagagcga aaagauggcc aaagauacau cugacgaggu cucccucaac      720

ccuaccagcg agaagcugaa caaucuucug gaagggaacg auuccgacaa ugaucucucu      780

cuggaggacu uuugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10684
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10684
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcaccagaa uuucacggag aagacgcaaa caacagagca      120

acaaaauucu uagaaucaau caaaggaaaa uucacaagcc caaaagaccc aaaaaaaaaa      180

gacucaauaa uaagcguaaa cucaauagac auagaaguaa caaaagaaag cccaauaaca      240

agcaacagca caauaauaaa cccaacaaac gaaacagaug acacagcugg aaauaaacca      300

aacuaccaaa gaaaaccccu agucagcuuc aaagaagacc ccacaccauc agacaaccca      360

uucagcaaac uauauaaaga aacaauagaa acauuugaca acaacgaaga agaaucauca      420

uacucauacg aagaaauaaa cgaccaaaca aacgacaaca uaaccgcaag auuagacaga      480

auagaugaaa aacuaucaga aauacuagga augcuacaca cauuaguagu agcaagcgca      540

ggaccaacau cagcaagaga cggaauaaga gacgcaauga uaggacucag agaagaaaug      600

auagaaaaaa uaagaacaga agcacuaaug acaaacgaca gauuagaagc aauggcaaga      660

cuaagaaaug aagaaucgga aaaaauggca aaagacacau cagacgaagu aagccuaaac      720

ccaacaucag aaaaauuaaa uaaccuacua gaaggaaacg acagcgacaa cgacuuauca      780

cuagaagacu ucuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10685
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design a-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10685
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcgcccgag uuccacggcg aggacgcgaa caaccgcgcg      120

acaaaguucc uagaaucaau caagggcaaa uucacgagcc cgaaagaccc caagaaaaag      180

gacucaauca uaagcgugaa cucgaucgac aucgagguca cgaaagagag cccgaucaca      240

agcaacagca ccauaauaaa cccgaccaac gaaacagacg acaccgcggg caacaaaccg      300

aacuaccaaa gaaaaccgcu cgugagcuuc aaagaagacc cgaccccaag cgacaacccg      360

uucucaaaac uauacaagga aacgaucgag accuucgaca acaacgagga agagagcucg      420

uacucguacg aggaaauaaa cgaccaaaca aacgacaaca uaaccgcacg ccuagacagg      480

aucgacgaaa aacucucgga aauacucggg augcuacaca cgcucguggu cgcgagcgca      540

ggcccgaccu cggccaggga cggcaucagg gacgcaauga uaggccugcg agaggaaaug      600

aucgagaaaa uacgcaccga agcacucaug accaacgaca gacucgaagc cauggccagg      660

cucaggaacg aagaauccga aaagauggcg aaagacaccu cggacgaggu cucgcucaac      720

cccacgagcg agaaacugaa caaccuacug gaagggaacg acagcgacaa cgaccuuucc      780

cucgaggacu ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga      840

aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  10686
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10686
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca acagggcuac uaaauuccua      300

gaaucaauaa agggcaaauu cacaucaccc aaagauccca agaaaaaaga uaguaucaua      360

ucugucaacu caauagauau agaaguaacc aaagaaagcc cuauaacauc aaauucaacu      420

auuaucaacc caacaaauga gacagaugau acugcaggga acaagcccaa uuaucaaaga      480

aaaccucuag uaaguuucaa agaagacccu acaccaagug auaaucccuu uucuaaacua      540

uacaaagaaa ccauagaaac auuugauaac aaugaagaag aauccagcua uucauacgaa      600

gaaauaaaug aucagacaaa cgauaauaua acagcaagau uagauaggau ugaugaaaaa      660

uuaagugaaa uacuaggaau gcuucacaca uuaguagugg caagugcagg accuacaucu      720

gcucgggaug guauaagaga ugccaugauu gguuuaagag aagaaaugau agaaaaaauc      780

agaacugaag cauuaaugac caaugacaga uuagaagcua uggcaagacu caggaaugag      840

gaaagugaaa agauggcaaa agacacauca gaugaagugu cucucaaucc aacaucagag      900

aaauugaaca accuauugga agggaaugau agugacaaug aucuaucacu ugaagauuuc      960

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10687
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10687
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgcgac caaguuccug      300

gagagcauca aggggaaguu caccuccccg aaggacccca agaagaagga cagcaucauc      360

uccgugaaca gcaucgacau cgaggucacg aaggaguccc ccaucaccag caacuccacc      420

aucaucaacc ccaccaacga gacggacgac accgccggca acaagccgaa cuaccagcgg      480

aagccccucg ugagcuucaa ggaggacccc acccccuccg acaacccguu cagcaagcug      540

uacaaggaga ccaucgagac guucgacaac aacgaggagg aguccagcua cuccuacgag      600

gagaucaacg accagaccaa cgacaacauc accgcccgcc uggaccggau cgacgagaag      660

cucagcgaga uccuggggau gcugcacacc cucguggucg ccuccgccgg ccccacgagc      720

gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg aggagaugau cgagaagauc      780

cggaccgagg cccugaugac caacgaccgc cucgaggcca uggcgcggcu gcgcaacgag      840

gaguccgaga agauggccaa ggacaccagc gacgaggugu cccugaaccc cacgagcgag      900

aagcucaaca accugcugga gggcaacgac agcgacaacg accucucccu ggaggacuuc      960

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10688
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10688
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgccac caaguuccuc      300

gaguccauca agggcaaguu caccuccccc aaggacccca agaagaagga cuccaucauc      360

uccgucaacu ccaucgacau cgaggucacc aaggaguccc ccaucaccuc caacuccacc      420

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagcgc      480

aagccccucg ucuccuucaa ggaggacccc acccccuccg acaaccccuu cuccaagcuc      540

uacaaggaga ccaucgagac cuucgacaac aacgaggagg aguccuccua cuccuacgag      600

gagaucaacg accagaccaa cgacaacauc accgcccgcc ucgaccgcau cgacgagaag      660

cucuccgaga uccucggcau gcuccacacc cucgucgucg ccuccgccgg ccccaccucc      720

gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg aggagaugau cgagaagauc      780

cgcaccgagg cccucaugac caacgaccgc cucgaggcca uggcccgccu ccgcaacgag      840

gaguccgaga agauggccaa ggacaccucc gacgaggucu cccucaaccc caccuccgag      900

aagcucaaca accuccucga gggcaacgac uccgacaacg accucucccu cgaggacuuc      960

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10689
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10689
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagcaac caaauuccug      300

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuaua      360

ucagugaaca guaucgauau ugaggucacu aaagaaagcc caaucacguc caauucuacc      420

auuaucaacc ccacaaauga gacugacgau accgccggaa acaagccuaa uuaccagagg      480

aaaccacucg uuucguucaa ggaggacccc acaccuucag auaacccauu uagcaaacuu      540

uauaaggaaa ccauagagac uuucgacaau aacgaagagg agaguuccua cucuuaugaa      600

gagaucaaug aucaaacaaa cgacaauauu accgcgcggc uggaucgcau cgacgaaaag      660

uugagcgaga uuuuagguau gcugcauacg cuagugguag cuuccgccgg ccccacuuca      720

gcacgagaug ggauccguga cgccaugaua ggacucagag aagagaugau ugagaaaauc      780

aggaccgaag cucugaugac aaacgaccgg cuugaggcaa uggcccgccu gagaaaugaa      840

gagagugaaa agauggcuaa agauacuagc gacgaggugu cuuugaaccc uaccuccgag      900

aagcucaaca aucugcugga aggcaacgau ucagacaaug aucucagcuu agaggacuuu      960

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10690
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10690
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaaguucg cccccgaguu ccacggcgag gacgccaaca acagagccac caaguuccug      300

gagagcauca agggcaaguu caccagcccc aaggacccca agaagaagga cagcaucauc      360

agcgugaaca gcaucgacau cgaggugacc aaggagagcc ccaucaccag caacagcacc      420

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagaga      480

aagccccugg ugagcuucaa ggaggacccc acccccagcg acaaccccuu cagcaagcug      540

uacaaggaga ccaucgagac cuucgacaac aacgaggagg agagcagcua cagcuacgag      600

gagaucaacg accagaccaa cgacaacauc accgccagac uggacagaau cgacgagaag      660

cugagcgaga uccugggcau gcugcacacc cugguggugg ccagcgccgg ccccaccagc      720

gccagagacg gcaucagaga cgccaugauc ggccugagag aggagaugau cgagaagauc      780

agaaccgagg cccugaugac caacgacaga cuggaggcca uggccagacu gagaaacgag      840

gagagcgaga agauggccaa ggacaccagc gacgagguga gccugaaccc caccagcgag      900

aagcugaaca accugcugga gggcaacgac agcgacaacg accugagccu ggaggacuuc      960

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10691
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10691
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagccac caaauuccug      300

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuauc      360

agcgugaacu ccauugauau cgaggucacg aaagaaucuc ccauuaccag caauuccaca      420

aucaucaacc cuaccaauga gacagacgau accgcgggaa acaagcccaa uuaccagcgg      480

aaaccucucg uuucuuucaa ggaggacccc acaccuagcg auaacccguu uuccaaacug      540

uauaaggaaa ccauugagac guucgacaau aacgaagagg agagcucuua cuccuaugaa      600

gagaucaaug aucaaaccaa cgacaauauu acagcucgcc uugauagaau cgacgaaaag      660

cugagcgaga uucucggcau gcugcauacc cuuguggugg ccucugccgg gcccacaucc      720

gcucgggaug gaauccgcga cgccaugauu ggccugagag aagagaugau cgagaaaauc      780

cggaccgaag cucucaugac gaacgaccgc cuggaggcca uggcgagacu gcggaaugaa      840

gagagcgaaa agauggccaa agauacaucu gacgaggucu cccucaaccc uaccagcgag      900

aagcugaaca aucuucugga agggaacgau uccgacaaug aucucucucu ggaggacuuu      960

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10692
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10692
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaaaaauucg caccagaauu ucacggagaa gacgcaaaca acagagcaac aaaauucuua      300

gaaucaauca aaggaaaauu cacaagccca aaagacccaa aaaaaaaaga cucaauaaua      360

agcguaaacu caauagacau agaaguaaca aaagaaagcc caauaacaag caacagcaca      420

auaauaaacc caacaaacga aacagaugac acagcuggaa auaaaccaaa cuaccaaaga      480

aaaccccuag ucagcuucaa agaagacccc acaccaucag acaacccauu cagcaaacua      540

uauaaagaaa caauagaaac auuugacaac aacgaagaag aaucaucaua cucauacgaa      600

gaaauaaacg accaaacaaa cgacaacaua accgcaagau uagacagaau agaugaaaaa      660

cuaucagaaa uacuaggaau gcuacacaca uuaguaguag caagcgcagg accaacauca      720

gcaagagacg gaauaagaga cgcaaugaua ggacucagag aagaaaugau agaaaaaaua      780

agaacagaag cacuaaugac aaacgacaga uuagaagcaa uggcaagacu aagaaaugaa      840

gaaucggaaa aaauggcaaa agacacauca gacgaaguaa gccuaaaccc aacaucagaa      900

aaauuaaaua accuacuaga aggaaacgac agcgacaacg acuuaucacu agaagacuuc      960

uaaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10693
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10693
gggagacgga gacggccugc aggaccugcu cucucagccc ucagccgagg ccuacgccga       60

gccgagugcg cagccgacga ccgggaggag ccgcagccuu caacucugag guacugugau      120

ccgcgcugcc cgccgggccg ccccaguccg cugcugcggc accuccuucc cucgcgcccu      180

cuucgcucgc cagcgccuuc ccugugagcc ugcgucaccg cggccgccaa gcuuaccaug      240

gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca accgcgcgac aaaguuccua      300

gaaucaauca agggcaaauu cacgagcccg aaagacccca agaaaaagga cucaaucaua      360

agcgugaacu cgaucgacau cgaggucacg aaagagagcc cgaucacaag caacagcacc      420

auaauaaacc cgaccaacga aacagacgac accgcgggca acaaaccgaa cuaccaaaga      480

aaaccgcucg ugagcuucaa agaagacccg accccaagcg acaacccguu cucaaaacua      540

uacaaggaaa cgaucgagac cuucgacaac aacgaggaag agagcucgua cucguacgag      600

gaaauaaacg accaaacaaa cgacaacaua accgcacgcc uagacaggau cgacgaaaaa      660

cucucggaaa uacucgggau gcuacacacg cucguggucg cgagcgcagg cccgaccucg      720

gccagggacg gcaucaggga cgcaaugaua ggccugcgag aggaaaugau cgagaaaaua      780

cgcaccgaag cacucaugac caacgacaga cucgaagcca uggccaggcu caggaacgaa      840

gaauccgaaa agauggcgaa agacaccucg gacgaggucu cgcucaaccc cacgagcgag      900

aaacugaaca accuacugga agggaacgac agcgacaacg accuuucccu cgaggacuuc      960

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa     1020

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10694
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10694
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca acagggcuac uaaauuccua      120

gaaucaauaa agggcaaauu cacaucaccc aaagauccca agaaaaaaga uaguaucaua      180

ucugucaacu caauagauau agaaguaacc aaagaaagcc cuauaacauc aaauucaacu      240

auuaucaacc caacaaauga gacagaugau acugcaggga acaagcccaa uuaucaaaga      300

aaaccucuag uaaguuucaa agaagacccu acaccaagug auaaucccuu uucuaaacua      360

uacaaagaaa ccauagaaac auuugauaac aaugaagaag aauccagcua uucauacgaa      420

gaaauaaaug aucagacaaa cgauaauaua acagcaagau uagauaggau ugaugaaaaa      480

uuaagugaaa uacuaggaau gcuucacaca uuaguagugg caagugcagg accuacaucu      540

gcucgggaug guauaagaga ugccaugauu gguuuaagag aagaaaugau agaaaaaauc      600

agaacugaag cauuaaugac caaugacaga uuagaagcua uggcaagacu caggaaugag      660

gaaagugaaa agauggcaaa agacacauca gaugaagugu cucucaaucc aacaucagag      720

aaauugaaca accuauugga agggaaugau agugacaaug aucuaucacu ugaagauuuc      780

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10695
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10695
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgcgac caaguuccug      120

gagagcauca aggggaaguu caccuccccg aaggacccca agaagaagga cagcaucauc      180

uccgugaaca gcaucgacau cgaggucacg aaggaguccc ccaucaccag caacuccacc      240

aucaucaacc ccaccaacga gacggacgac accgccggca acaagccgaa cuaccagcgg      300

aagccccucg ugagcuucaa ggaggacccc acccccuccg acaacccguu cagcaagcug      360

uacaaggaga ccaucgagac guucgacaac aacgaggagg aguccagcua cuccuacgag      420

gagaucaacg accagaccaa cgacaacauc accgcccgcc uggaccggau cgacgagaag      480

cucagcgaga uccuggggau gcugcacacc cucguggucg ccuccgccgg ccccacgagc      540

gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg aggagaugau cgagaagauc      600

cggaccgagg cccugaugac caacgaccgc cucgaggcca uggcgcggcu gcgcaacgag      660

gaguccgaga agauggccaa ggacaccagc gacgaggugu cccugaaccc cacgagcgag      720

aagcucaaca accugcugga gggcaacgac agcgacaacg accucucccu ggaggacuuc      780

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10696
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10696
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgccac caaguuccuc      120

gaguccauca agggcaaguu caccuccccc aaggacccca agaagaagga cuccaucauc      180

uccgucaacu ccaucgacau cgaggucacc aaggaguccc ccaucaccuc caacuccacc      240

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagcgc      300

aagccccucg ucuccuucaa ggaggacccc acccccuccg acaaccccuu cuccaagcuc      360

uacaaggaga ccaucgagac cuucgacaac aacgaggagg aguccuccua cuccuacgag      420

gagaucaacg accagaccaa cgacaacauc accgcccgcc ucgaccgcau cgacgagaag      480

cucuccgaga uccucggcau gcuccacacc cucgucgucg ccuccgccgg ccccaccucc      540

gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg aggagaugau cgagaagauc      600

cgcaccgagg cccucaugac caacgaccgc cucgaggcca uggcccgccu ccgcaacgag      660

gaguccgaga agauggccaa ggacaccucc gacgaggucu cccucaaccc caccuccgag      720

aagcucaaca accuccucga gggcaacgac uccgacaacg accucucccu cgaggacuuc      780

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10697
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10697
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagcaac caaauuccug      120

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuaua      180

ucagugaaca guaucgauau ugaggucacu aaagaaagcc caaucacguc caauucuacc      240

auuaucaacc ccacaaauga gacugacgau accgccggaa acaagccuaa uuaccagagg      300

aaaccacucg uuucguucaa ggaggacccc acaccuucag auaacccauu uagcaaacuu      360

uauaaggaaa ccauagagac uuucgacaau aacgaagagg agaguuccua cucuuaugaa      420

gagaucaaug aucaaacaaa cgacaauauu accgcgcggc uggaucgcau cgacgaaaag      480

uugagcgaga uuuuagguau gcugcauacg cuagugguag cuuccgccgg ccccacuuca      540

gcacgagaug ggauccguga cgccaugaua ggacucagag aagagaugau ugagaaaauc      600

aggaccgaag cucugaugac aaacgaccgg cuugaggcaa uggcccgccu gagaaaugaa      660

gagagugaaa agauggcuaa agauacuagc gacgaggugu cuuugaaccc uaccuccgag      720

aagcucaaca aucugcugga aggcaacgau ucagacaaug aucucagcuu agaggacuuu      780

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10698
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10698
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaaguucg cccccgaguu ccacggcgag gacgccaaca acagagccac caaguuccug      120

gagagcauca agggcaaguu caccagcccc aaggacccca agaagaagga cagcaucauc      180

agcgugaaca gcaucgacau cgaggugacc aaggagagcc ccaucaccag caacagcacc      240

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagaga      300

aagccccugg ugagcuucaa ggaggacccc acccccagcg acaaccccuu cagcaagcug      360

uacaaggaga ccaucgagac cuucgacaac aacgaggagg agagcagcua cagcuacgag      420

gagaucaacg accagaccaa cgacaacauc accgccagac uggacagaau cgacgagaag      480

cugagcgaga uccugggcau gcugcacacc cugguggugg ccagcgccgg ccccaccagc      540

gccagagacg gcaucagaga cgccaugauc ggccugagag aggagaugau cgagaagauc      600

agaaccgagg cccugaugac caacgacaga cuggaggcca uggccagacu gagaaacgag      660

gagagcgaga agauggccaa ggacaccagc gacgagguga gccugaaccc caccagcgag      720

aagcugaaca accugcugga gggcaacgac agcgacaacg accugagccu ggaggacuuc      780

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10699
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10699
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagccac caaauuccug      120

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuauc      180

agcgugaacu ccauugauau cgaggucacg aaagaaucuc ccauuaccag caauuccaca      240

aucaucaacc cuaccaauga gacagacgau accgcgggaa acaagcccaa uuaccagcgg      300

aaaccucucg uuucuuucaa ggaggacccc acaccuagcg auaacccguu uuccaaacug      360

uauaaggaaa ccauugagac guucgacaau aacgaagagg agagcucuua cuccuaugaa      420

gagaucaaug aucaaaccaa cgacaauauu acagcucgcc uugauagaau cgacgaaaag      480

cugagcgaga uucucggcau gcugcauacc cuuguggugg ccucugccgg gcccacaucc      540

gcucgggaug gaauccgcga cgccaugauu ggccugagag aagagaugau cgagaaaauc      600

cggaccgaag cucucaugac gaacgaccgc cuggaggcca uggcgagacu gcggaaugaa      660

gagagcgaaa agauggccaa agauacaucu gacgaggucu cccucaaccc uaccagcgag      720

aagcugaaca aucuucugga agggaacgau uccgacaaug aucucucucu ggaggacuuu      780

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10700
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10700
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaaaaauucg caccagaauu ucacggagaa gacgcaaaca acagagcaac aaaauucuua      120

gaaucaauca aaggaaaauu cacaagccca aaagacccaa aaaaaaaaga cucaauaaua      180

agcguaaacu caauagacau agaaguaaca aaagaaagcc caauaacaag caacagcaca      240

auaauaaacc caacaaacga aacagaugac acagcuggaa auaaaccaaa cuaccaaaga      300

aaaccccuag ucagcuucaa agaagacccc acaccaucag acaacccauu cagcaaacua      360

uauaaagaaa caauagaaac auuugacaac aacgaagaag aaucaucaua cucauacgaa      420

gaaauaaacg accaaacaaa cgacaacaua accgcaagau uagacagaau agaugaaaaa      480

cuaucagaaa uacuaggaau gcuacacaca uuaguaguag caagcgcagg accaacauca      540

gcaagagacg gaauaagaga cgcaaugaua ggacucagag aagaaaugau agaaaaaaua      600

agaacagaag cacuaaugac aaacgacaga uuagaagcaa uggcaagacu aagaaaugaa      660

gaaucggaaa aaauggcaaa agacacauca gacgaaguaa gccuaaaccc aacaucagaa      720

aaauuaaaua accuacuaga aggaaacgac agcgacaacg acuuaucacu agaagacuuc      780

uaaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10701
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10701
gggagagccu cugcuggagu ccggggagug gcguuggcug cuagagcgaa gcuuaccaug       60

gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca accgcgcgac aaaguuccua      120

gaaucaauca agggcaaauu cacgagcccg aaagacccca agaaaaagga cucaaucaua      180

agcgugaacu cgaucgacau cgaggucacg aaagagagcc cgaucacaag caacagcacc      240

auaauaaacc cgaccaacga aacagacgac accgcgggca acaaaccgaa cuaccaaaga      300

aaaccgcucg ugagcuucaa agaagacccg accccaagcg acaacccguu cucaaaacua      360

uacaaggaaa cgaucgagac cuucgacaac aacgaggaag agagcucgua cucguacgag      420

gaaauaaacg accaaacaaa cgacaacaua accgcacgcc uagacaggau cgacgaaaaa      480

cucucggaaa uacucgggau gcuacacacg cucguggucg cgagcgcagg cccgaccucg      540

gccagggacg gcaucaggga cgcaaugaua ggccugcgag aggaaaugau cgagaaaaua      600

cgcaccgaag cacucaugac caacgacaga cucgaagcca uggccaggcu caggaacgaa      660

gaauccgaaa agauggcgaa agacaccucg gacgaggucu cgcucaaccc cacgagcgag      720

aaacugaaca accuacugga agggaacgac agcgacaacg accuuucccu cgaggacuuc      780

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      840

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc      960

cccccccaaa ggcucuuuuc agagccacca gaauu                                 995


<210>  10702
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10702
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca      120

acagggcuac uaaauuccua gaaucaauaa agggcaaauu cacaucaccc aaagauccca      180

agaaaaaaga uaguaucaua ucugucaacu caauagauau agaaguaacc aaagaaagcc      240

cuauaacauc aaauucaacu auuaucaacc caacaaauga gacagaugau acugcaggga      300

acaagcccaa uuaucaaaga aaaccucuag uaaguuucaa agaagacccu acaccaagug      360

auaaucccuu uucuaaacua uacaaagaaa ccauagaaac auuugauaac aaugaagaag      420

aauccagcua uucauacgaa gaaauaaaug aucagacaaa cgauaauaua acagcaagau      480

uagauaggau ugaugaaaaa uuaagugaaa uacuaggaau gcuucacaca uuaguagugg      540

caagugcagg accuacaucu gcucgggaug guauaagaga ugccaugauu gguuuaagag      600

aagaaaugau agaaaaaauc agaacugaag cauuaaugac caaugacaga uuagaagcua      660

uggcaagacu caggaaugag gaaagugaaa agauggcaaa agacacauca gaugaagugu      720

cucucaaucc aacaucagag aaauugaaca accuauugga agggaaugau agugacaaug      780

aucuaucacu ugaagauuuc ugaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10703
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10703
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgcgac caaguuccug gagagcauca aggggaaguu caccuccccg aaggacccca      180

agaagaagga cagcaucauc uccgugaaca gcaucgacau cgaggucacg aaggaguccc      240

ccaucaccag caacuccacc aucaucaacc ccaccaacga gacggacgac accgccggca      300

acaagccgaa cuaccagcgg aagccccucg ugagcuucaa ggaggacccc acccccuccg      360

acaacccguu cagcaagcug uacaaggaga ccaucgagac guucgacaac aacgaggagg      420

aguccagcua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

uggaccggau cgacgagaag cucagcgaga uccuggggau gcugcacacc cucguggucg      540

ccuccgccgg ccccacgagc gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg      600

aggagaugau cgagaagauc cggaccgagg cccugaugac caacgaccgc cucgaggcca      660

uggcgcggcu gcgcaacgag gaguccgaga agauggccaa ggacaccagc gacgaggugu      720

cccugaaccc cacgagcgag aagcucaaca accugcugga gggcaacgac agcgacaacg      780

accucucccu ggaggacuuc ugaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10704
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10704
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgccac caaguuccuc gaguccauca agggcaaguu caccuccccc aaggacccca      180

agaagaagga cuccaucauc uccgucaacu ccaucgacau cgaggucacc aaggaguccc      240

ccaucaccuc caacuccacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagcgc aagccccucg ucuccuucaa ggaggacccc acccccuccg      360

acaaccccuu cuccaagcuc uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

aguccuccua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

ucgaccgcau cgacgagaag cucuccgaga uccucggcau gcuccacacc cucgucgucg      540

ccuccgccgg ccccaccucc gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg      600

aggagaugau cgagaagauc cgcaccgagg cccucaugac caacgaccgc cucgaggcca      660

uggcccgccu ccgcaacgag gaguccgaga agauggccaa ggacaccucc gacgaggucu      720

cccucaaccc caccuccgag aagcucaaca accuccucga gggcaacgac uccgacaacg      780

accucucccu cgaggacuuc ugaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10705
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10705
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagcaac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuaua ucagugaaca guaucgauau ugaggucacu aaagaaagcc      240

caaucacguc caauucuacc auuaucaacc ccacaaauga gacugacgau accgccggaa      300

acaagccuaa uuaccagagg aaaccacucg uuucguucaa ggaggacccc acaccuucag      360

auaacccauu uagcaaacuu uauaaggaaa ccauagagac uuucgacaau aacgaagagg      420

agaguuccua cucuuaugaa gagaucaaug aucaaacaaa cgacaauauu accgcgcggc      480

uggaucgcau cgacgaaaag uugagcgaga uuuuagguau gcugcauacg cuagugguag      540

cuuccgccgg ccccacuuca gcacgagaug ggauccguga cgccaugaua ggacucagag      600

aagagaugau ugagaaaauc aggaccgaag cucugaugac aaacgaccgg cuugaggcaa      660

uggcccgccu gagaaaugaa gagagugaaa agauggcuaa agauacuagc gacgaggugu      720

cuuugaaccc uaccuccgag aagcucaaca aucugcugga aggcaacgau ucagacaaug      780

aucucagcuu agaggacuuu ugaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10706
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10706
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

acagagccac caaguuccug gagagcauca agggcaaguu caccagcccc aaggacccca      180

agaagaagga cagcaucauc agcgugaaca gcaucgacau cgaggugacc aaggagagcc      240

ccaucaccag caacagcacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagaga aagccccugg ugagcuucaa ggaggacccc acccccagcg      360

acaaccccuu cagcaagcug uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

agagcagcua cagcuacgag gagaucaacg accagaccaa cgacaacauc accgccagac      480

uggacagaau cgacgagaag cugagcgaga uccugggcau gcugcacacc cugguggugg      540

ccagcgccgg ccccaccagc gccagagacg gcaucagaga cgccaugauc ggccugagag      600

aggagaugau cgagaagauc agaaccgagg cccugaugac caacgacaga cuggaggcca      660

uggccagacu gagaaacgag gagagcgaga agauggccaa ggacaccagc gacgagguga      720

gccugaaccc caccagcgag aagcugaaca accugcugga gggcaacgac agcgacaacg      780

accugagccu ggaggacuuc ugaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10707
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10707
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagccac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuauc agcgugaacu ccauugauau cgaggucacg aaagaaucuc      240

ccauuaccag caauuccaca aucaucaacc cuaccaauga gacagacgau accgcgggaa      300

acaagcccaa uuaccagcgg aaaccucucg uuucuuucaa ggaggacccc acaccuagcg      360

auaacccguu uuccaaacug uauaaggaaa ccauugagac guucgacaau aacgaagagg      420

agagcucuua cuccuaugaa gagaucaaug aucaaaccaa cgacaauauu acagcucgcc      480

uugauagaau cgacgaaaag cugagcgaga uucucggcau gcugcauacc cuuguggugg      540

ccucugccgg gcccacaucc gcucgggaug gaauccgcga cgccaugauu ggccugagag      600

aagagaugau cgagaaaauc cggaccgaag cucucaugac gaacgaccgc cuggaggcca      660

uggcgagacu gcggaaugaa gagagcgaaa agauggccaa agauacaucu gacgaggucu      720

cccucaaccc uaccagcgag aagcugaaca aucuucugga agggaacgau uccgacaaug      780

aucucucucu ggaggacuuu ugaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10708
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10708
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg caccagaauu ucacggagaa gacgcaaaca      120

acagagcaac aaaauucuua gaaucaauca aaggaaaauu cacaagccca aaagacccaa      180

aaaaaaaaga cucaauaaua agcguaaacu caauagacau agaaguaaca aaagaaagcc      240

caauaacaag caacagcaca auaauaaacc caacaaacga aacagaugac acagcuggaa      300

auaaaccaaa cuaccaaaga aaaccccuag ucagcuucaa agaagacccc acaccaucag      360

acaacccauu cagcaaacua uauaaagaaa caauagaaac auuugacaac aacgaagaag      420

aaucaucaua cucauacgaa gaaauaaacg accaaacaaa cgacaacaua accgcaagau      480

uagacagaau agaugaaaaa cuaucagaaa uacuaggaau gcuacacaca uuaguaguag      540

caagcgcagg accaacauca gcaagagacg gaauaagaga cgcaaugaua ggacucagag      600

aagaaaugau agaaaaaaua agaacagaag cacuaaugac aaacgacaga uuagaagcaa      660

uggcaagacu aagaaaugaa gaaucggaaa aaauggcaaa agacacauca gacgaaguaa      720

gccuaaaccc aacaucagaa aaauuaaaua accuacuaga aggaaacgac agcgacaacg      780

acuuaucacu agaagacuuc uaaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10709
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10709
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca      120

accgcgcgac aaaguuccua gaaucaauca agggcaaauu cacgagcccg aaagacccca      180

agaaaaagga cucaaucaua agcgugaacu cgaucgacau cgaggucacg aaagagagcc      240

cgaucacaag caacagcacc auaauaaacc cgaccaacga aacagacgac accgcgggca      300

acaaaccgaa cuaccaaaga aaaccgcucg ugagcuucaa agaagacccg accccaagcg      360

acaacccguu cucaaaacua uacaaggaaa cgaucgagac cuucgacaac aacgaggaag      420

agagcucgua cucguacgag gaaauaaacg accaaacaaa cgacaacaua accgcacgcc      480

uagacaggau cgacgaaaaa cucucggaaa uacucgggau gcuacacacg cucguggucg      540

cgagcgcagg cccgaccucg gccagggacg gcaucaggga cgcaaugaua ggccugcgag      600

aggaaaugau cgagaaaaua cgcaccgaag cacucaugac caacgacaga cucgaagcca      660

uggccaggcu caggaacgaa gaauccgaaa agauggcgaa agacaccucg gacgaggucu      720

cgcucaaccc cacgagcgag aaacugaaca accuacugga agggaacgac agcgacaacg      780

accuuucccu cgaggacuuc ugaggacuag uguccaccug ucccuccugg gcugcuggau      840

ugucucguuu uccugccaaa uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10710
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10710
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca      120

acagggcuac uaaauuccua gaaucaauaa agggcaaauu cacaucaccc aaagauccca      180

agaaaaaaga uaguaucaua ucugucaacu caauagauau agaaguaacc aaagaaagcc      240

cuauaacauc aaauucaacu auuaucaacc caacaaauga gacagaugau acugcaggga      300

acaagcccaa uuaucaaaga aaaccucuag uaaguuucaa agaagacccu acaccaagug      360

auaaucccuu uucuaaacua uacaaagaaa ccauagaaac auuugauaac aaugaagaag      420

aauccagcua uucauacgaa gaaauaaaug aucagacaaa cgauaauaua acagcaagau      480

uagauaggau ugaugaaaaa uuaagugaaa uacuaggaau gcuucacaca uuaguagugg      540

caagugcagg accuacaucu gcucgggaug guauaagaga ugccaugauu gguuuaagag      600

aagaaaugau agaaaaaauc agaacugaag cauuaaugac caaugacaga uuagaagcua      660

uggcaagacu caggaaugag gaaagugaaa agauggcaaa agacacauca gaugaagugu      720

cucucaaucc aacaucagag aaauugaaca accuauugga agggaaugau agugacaaug      780

aucuaucacu ugaagauuuc ugaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10711
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10711
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgcgac caaguuccug gagagcauca aggggaaguu caccuccccg aaggacccca      180

agaagaagga cagcaucauc uccgugaaca gcaucgacau cgaggucacg aaggaguccc      240

ccaucaccag caacuccacc aucaucaacc ccaccaacga gacggacgac accgccggca      300

acaagccgaa cuaccagcgg aagccccucg ugagcuucaa ggaggacccc acccccuccg      360

acaacccguu cagcaagcug uacaaggaga ccaucgagac guucgacaac aacgaggagg      420

aguccagcua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

uggaccggau cgacgagaag cucagcgaga uccuggggau gcugcacacc cucguggucg      540

ccuccgccgg ccccacgagc gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg      600

aggagaugau cgagaagauc cggaccgagg cccugaugac caacgaccgc cucgaggcca      660

uggcgcggcu gcgcaacgag gaguccgaga agauggccaa ggacaccagc gacgaggugu      720

cccugaaccc cacgagcgag aagcucaaca accugcugga gggcaacgac agcgacaacg      780

accucucccu ggaggacuuc ugaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10712
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10712
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgccac caaguuccuc gaguccauca agggcaaguu caccuccccc aaggacccca      180

agaagaagga cuccaucauc uccgucaacu ccaucgacau cgaggucacc aaggaguccc      240

ccaucaccuc caacuccacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagcgc aagccccucg ucuccuucaa ggaggacccc acccccuccg      360

acaaccccuu cuccaagcuc uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

aguccuccua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

ucgaccgcau cgacgagaag cucuccgaga uccucggcau gcuccacacc cucgucgucg      540

ccuccgccgg ccccaccucc gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg      600

aggagaugau cgagaagauc cgcaccgagg cccucaugac caacgaccgc cucgaggcca      660

uggcccgccu ccgcaacgag gaguccgaga agauggccaa ggacaccucc gacgaggucu      720

cccucaaccc caccuccgag aagcucaaca accuccucga gggcaacgac uccgacaacg      780

accucucccu cgaggacuuc ugaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10713
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10713
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagcaac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuaua ucagugaaca guaucgauau ugaggucacu aaagaaagcc      240

caaucacguc caauucuacc auuaucaacc ccacaaauga gacugacgau accgccggaa      300

acaagccuaa uuaccagagg aaaccacucg uuucguucaa ggaggacccc acaccuucag      360

auaacccauu uagcaaacuu uauaaggaaa ccauagagac uuucgacaau aacgaagagg      420

agaguuccua cucuuaugaa gagaucaaug aucaaacaaa cgacaauauu accgcgcggc      480

uggaucgcau cgacgaaaag uugagcgaga uuuuagguau gcugcauacg cuagugguag      540

cuuccgccgg ccccacuuca gcacgagaug ggauccguga cgccaugaua ggacucagag      600

aagagaugau ugagaaaauc aggaccgaag cucugaugac aaacgaccgg cuugaggcaa      660

uggcccgccu gagaaaugaa gagagugaaa agauggcuaa agauacuagc gacgaggugu      720

cuuugaaccc uaccuccgag aagcucaaca aucugcugga aggcaacgau ucagacaaug      780

aucucagcuu agaggacuuu ugaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10714
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10714
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

acagagccac caaguuccug gagagcauca agggcaaguu caccagcccc aaggacccca      180

agaagaagga cagcaucauc agcgugaaca gcaucgacau cgaggugacc aaggagagcc      240

ccaucaccag caacagcacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagaga aagccccugg ugagcuucaa ggaggacccc acccccagcg      360

acaaccccuu cagcaagcug uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

agagcagcua cagcuacgag gagaucaacg accagaccaa cgacaacauc accgccagac      480

uggacagaau cgacgagaag cugagcgaga uccugggcau gcugcacacc cugguggugg      540

ccagcgccgg ccccaccagc gccagagacg gcaucagaga cgccaugauc ggccugagag      600

aggagaugau cgagaagauc agaaccgagg cccugaugac caacgacaga cuggaggcca      660

uggccagacu gagaaacgag gagagcgaga agauggccaa ggacaccagc gacgagguga      720

gccugaaccc caccagcgag aagcugaaca accugcugga gggcaacgac agcgacaacg      780

accugagccu ggaggacuuc ugaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10715
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10715
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagccac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuauc agcgugaacu ccauugauau cgaggucacg aaagaaucuc      240

ccauuaccag caauuccaca aucaucaacc cuaccaauga gacagacgau accgcgggaa      300

acaagcccaa uuaccagcgg aaaccucucg uuucuuucaa ggaggacccc acaccuagcg      360

auaacccguu uuccaaacug uauaaggaaa ccauugagac guucgacaau aacgaagagg      420

agagcucuua cuccuaugaa gagaucaaug aucaaaccaa cgacaauauu acagcucgcc      480

uugauagaau cgacgaaaag cugagcgaga uucucggcau gcugcauacc cuuguggugg      540

ccucugccgg gcccacaucc gcucgggaug gaauccgcga cgccaugauu ggccugagag      600

aagagaugau cgagaaaauc cggaccgaag cucucaugac gaacgaccgc cuggaggcca      660

uggcgagacu gcggaaugaa gagagcgaaa agauggccaa agauacaucu gacgaggucu      720

cccucaaccc uaccagcgag aagcugaaca aucuucugga agggaacgau uccgacaaug      780

aucucucucu ggaggacuuu ugaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10716
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10716
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg caccagaauu ucacggagaa gacgcaaaca      120

acagagcaac aaaauucuua gaaucaauca aaggaaaauu cacaagccca aaagacccaa      180

aaaaaaaaga cucaauaaua agcguaaacu caauagacau agaaguaaca aaagaaagcc      240

caauaacaag caacagcaca auaauaaacc caacaaacga aacagaugac acagcuggaa      300

auaaaccaaa cuaccaaaga aaaccccuag ucagcuucaa agaagacccc acaccaucag      360

acaacccauu cagcaaacua uauaaagaaa caauagaaac auuugacaac aacgaagaag      420

aaucaucaua cucauacgaa gaaauaaacg accaaacaaa cgacaacaua accgcaagau      480

uagacagaau agaugaaaaa cuaucagaaa uacuaggaau gcuacacaca uuaguaguag      540

caagcgcagg accaacauca gcaagagacg gaauaagaga cgcaaugaua ggacucagag      600

aagaaaugau agaaaaaaua agaacagaag cacuaaugac aaacgacaga uuagaagcaa      660

uggcaagacu aagaaaugaa gaaucggaaa aaauggcaaa agacacauca gacgaaguaa      720

gccuaaaccc aacaucagaa aaauuaaaua accuacuaga aggaaacgac agcgacaacg      780

acuuaucacu agaagacuuc uaaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10717
<211>  1066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10717
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca      120

accgcgcgac aaaguuccua gaaucaauca agggcaaauu cacgagcccg aaagacccca      180

agaaaaagga cucaaucaua agcgugaacu cgaucgacau cgaggucacg aaagagagcc      240

cgaucacaag caacagcacc auaauaaacc cgaccaacga aacagacgac accgcgggca      300

acaaaccgaa cuaccaaaga aaaccgcucg ugagcuucaa agaagacccg accccaagcg      360

acaacccguu cucaaaacua uacaaggaaa cgaucgagac cuucgacaac aacgaggaag      420

agagcucgua cucguacgag gaaauaaacg accaaacaaa cgacaacaua accgcacgcc      480

uagacaggau cgacgaaaaa cucucggaaa uacucgggau gcuacacacg cucguggucg      540

cgagcgcagg cccgaccucg gccagggacg gcaucaggga cgcaaugaua ggccugcgag      600

aggaaaugau cgagaaaaua cgcaccgaag cacucaugac caacgacaga cucgaagcca      660

uggccaggcu caggaacgaa gaauccgaaa agauggcgaa agacaccucg gacgaggucu      720

cgcucaaccc cacgagcgag aaacugaaca accuacugga agggaacgac agcgacaacg      780

accuuucccu cgaggacuuc ugaggacuag uaauaaggaa acuguaugaa ugucuguggg      840

caggaaguga agagauccuu cuguaaaggu uuuuggaauu augucugcug aauaauaaac      900

uuuuuugaaa uaauaaaucu gguagaaaaa ugagaucuaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1020

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1066


<210>  10718
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10718
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aguuugcucc ugaauuccau ggagaagaug caaacaacag ggcuacuaaa      180

uuccuagaau caauaaaggg caaauucaca ucacccaaag aucccaagaa aaaagauagu      240

aucauaucug ucaacucaau agauauagaa guaaccaaag aaagcccuau aacaucaaau      300

ucaacuauua ucaacccaac aaaugagaca gaugauacug cagggaacaa gcccaauuau      360

caaagaaaac cucuaguaag uuucaaagaa gacccuacac caagugauaa ucccuuuucu      420

aaacuauaca aagaaaccau agaaacauuu gauaacaaug aagaagaauc cagcuauuca      480

uacgaagaaa uaaaugauca gacaaacgau aauauaacag caagauuaga uaggauugau      540

gaaaaauuaa gugaaauacu aggaaugcuu cacacauuag uaguggcaag ugcaggaccu      600

acaucugcuc gggaugguau aagagaugcc augauugguu uaagagaaga aaugauagaa      660

aaaaucagaa cugaagcauu aaugaccaau gacagauuag aagcuauggc aagacucagg      720

aaugaggaaa gugaaaagau ggcaaaagac acaucagaug aagugucucu caauccaaca      780

ucagagaaau ugaacaaccu auuggaaggg aaugauagug acaaugaucu aucacuugaa      840

gauuucugag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10719
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10719
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgcgaccaag      180

uuccuggaga gcaucaaggg gaaguucacc uccccgaagg accccaagaa gaaggacagc      240

aucaucuccg ugaacagcau cgacaucgag gucacgaagg agucccccau caccagcaac      300

uccaccauca ucaaccccac caacgagacg gacgacaccg ccggcaacaa gccgaacuac      360

cagcggaagc cccucgugag cuucaaggag gaccccaccc ccuccgacaa cccguucagc      420

aagcuguaca aggagaccau cgagacguuc gacaacaacg aggaggaguc cagcuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccugga ccggaucgac      540

gagaagcuca gcgagauccu ggggaugcug cacacccucg uggucgccuc cgccggcccc      600

acgagcgcgc gcgacgggau ccgggacgcc augaucggcc ugcgcgagga gaugaucgag      660

aagauccgga ccgaggcccu gaugaccaac gaccgccucg aggccauggc gcggcugcgc      720

aacgaggagu ccgagaagau ggccaaggac accagcgacg aggugucccu gaaccccacg      780

agcgagaagc ucaacaaccu gcuggagggc aacgacagcg acaacgaccu cucccuggag      840

gacuucugag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10720
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10720
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgccaccaag      180

uuccucgagu ccaucaaggg caaguucacc ucccccaagg accccaagaa gaaggacucc      240

aucaucuccg ucaacuccau cgacaucgag gucaccaagg agucccccau caccuccaac      300

uccaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagcgcaagc cccucgucuc cuucaaggag gaccccaccc ccuccgacaa ccccuucucc      420

aagcucuaca aggagaccau cgagaccuuc gacaacaacg aggaggaguc cuccuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccucga ccgcaucgac      540

gagaagcucu ccgagauccu cggcaugcuc cacacccucg ucgucgccuc cgccggcccc      600

accuccgccc gcgacggcau ccgcgacgcc augaucggcc uccgcgagga gaugaucgag      660

aagauccgca ccgaggcccu caugaccaac gaccgccucg aggccauggc ccgccuccgc      720

aacgaggagu ccgagaagau ggccaaggac accuccgacg aggucucccu caaccccacc      780

uccgagaagc ucaacaaccu ccucgagggc aacgacuccg acaacgaccu cucccucgag      840

gacuucugag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10721
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10721
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agcaaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuauaucag ugaacaguau cgauauugag gucacuaaag aaagcccaau cacguccaau      300

ucuaccauua ucaaccccac aaaugagacu gacgauaccg ccggaaacaa gccuaauuac      360

cagaggaaac cacucguuuc guucaaggag gaccccacac cuucagauaa cccauuuagc      420

aaacuuuaua aggaaaccau agagacuuuc gacaauaacg aagaggagag uuccuacucu      480

uaugaagaga ucaaugauca aacaaacgac aauauuaccg cgcggcugga ucgcaucgac      540

gaaaaguuga gcgagauuuu agguaugcug cauacgcuag ugguagcuuc cgccggcccc      600

acuucagcac gagaugggau ccgugacgcc augauaggac ucagagaaga gaugauugag      660

aaaaucagga ccgaagcucu gaugacaaac gaccggcuug aggcaauggc ccgccugaga      720

aaugaagaga gugaaaagau ggcuaaagau acuagcgacg aggugucuuu gaacccuacc      780

uccgagaagc ucaacaaucu gcuggaaggc aacgauucag acaaugaucu cagcuuagag      840

gacuuuugag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10722
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10722
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaacag agccaccaag      180

uuccuggaga gcaucaaggg caaguucacc agccccaagg accccaagaa gaaggacagc      240

aucaucagcg ugaacagcau cgacaucgag gugaccaagg agagccccau caccagcaac      300

agcaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagagaaagc cccuggugag cuucaaggag gaccccaccc ccagcgacaa ccccuucagc      420

aagcuguaca aggagaccau cgagaccuuc gacaacaacg aggaggagag cagcuacagc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg ccagacugga cagaaucgac      540

gagaagcuga gcgagauccu gggcaugcug cacacccugg ugguggccag cgccggcccc      600

accagcgcca gagacggcau cagagacgcc augaucggcc ugagagagga gaugaucgag      660

aagaucagaa ccgaggcccu gaugaccaac gacagacugg aggccauggc cagacugaga      720

aacgaggaga gcgagaagau ggccaaggac accagcgacg aggugagccu gaaccccacc      780

agcgagaagc ugaacaaccu gcuggagggc aacgacagcg acaacgaccu gagccuggag      840

gacuucugag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10723
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10723
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agccaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuaucagcg ugaacuccau ugauaucgag gucacgaaag aaucucccau uaccagcaau      300

uccacaauca ucaacccuac caaugagaca gacgauaccg cgggaaacaa gcccaauuac      360

cagcggaaac cucucguuuc uuucaaggag gaccccacac cuagcgauaa cccguuuucc      420

aaacuguaua aggaaaccau ugagacguuc gacaauaacg aagaggagag cucuuacucc      480

uaugaagaga ucaaugauca aaccaacgac aauauuacag cucgccuuga uagaaucgac      540

gaaaagcuga gcgagauucu cggcaugcug cauacccuug ugguggccuc ugccgggccc      600

acauccgcuc gggauggaau ccgcgacgcc augauuggcc ugagagaaga gaugaucgag      660

aaaauccgga ccgaagcucu caugacgaac gaccgccugg aggccauggc gagacugcgg      720

aaugaagaga gcgaaaagau ggccaaagau acaucugacg aggucucccu caacccuacc      780

agcgagaagc ugaacaaucu ucuggaaggg aacgauuccg acaaugaucu cucucuggag      840

gacuuuugag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10724
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10724
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcacc agaauuucac ggagaagacg caaacaacag agcaacaaaa      180

uucuuagaau caaucaaagg aaaauucaca agcccaaaag acccaaaaaa aaaagacuca      240

auaauaagcg uaaacucaau agacauagaa guaacaaaag aaagcccaau aacaagcaac      300

agcacaauaa uaaacccaac aaacgaaaca gaugacacag cuggaaauaa accaaacuac      360

caaagaaaac cccuagucag cuucaaagaa gaccccacac caucagacaa cccauucagc      420

aaacuauaua aagaaacaau agaaacauuu gacaacaacg aagaagaauc aucauacuca      480

uacgaagaaa uaaacgacca aacaaacgac aacauaaccg caagauuaga cagaauagau      540

gaaaaacuau cagaaauacu aggaaugcua cacacauuag uaguagcaag cgcaggacca      600

acaucagcaa gagacggaau aagagacgca augauaggac ucagagaaga aaugauagaa      660

aaaauaagaa cagaagcacu aaugacaaac gacagauuag aagcaauggc aagacuaaga      720

aaugaagaau cggaaaaaau ggcaaaagac acaucagacg aaguaagccu aaacccaaca      780

ucagaaaaau uaaauaaccu acuagaagga aacgacagcg acaacgacuu aucacuagaa      840

gacuucuaag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10725
<211>  1128
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design b-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10725
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcgcc cgaguuccac ggcgaggacg cgaacaaccg cgcgacaaag      180

uuccuagaau caaucaaggg caaauucacg agcccgaaag accccaagaa aaaggacuca      240

aucauaagcg ugaacucgau cgacaucgag gucacgaaag agagcccgau cacaagcaac      300

agcaccauaa uaaacccgac caacgaaaca gacgacaccg cgggcaacaa accgaacuac      360

caaagaaaac cgcucgugag cuucaaagaa gacccgaccc caagcgacaa cccguucuca      420

aaacuauaca aggaaacgau cgagaccuuc gacaacaacg aggaagagag cucguacucg      480

uacgaggaaa uaaacgacca aacaaacgac aacauaaccg cacgccuaga caggaucgac      540

gaaaaacucu cggaaauacu cgggaugcua cacacgcucg uggucgcgag cgcaggcccg      600

accucggcca gggacggcau cagggacgca augauaggcc ugcgagagga aaugaucgag      660

aaaauacgca ccgaagcacu caugaccaac gacagacucg aagccauggc caggcucagg      720

aacgaagaau ccgaaaagau ggcgaaagac accucggacg aggucucgcu caaccccacg      780

agcgagaaac ugaacaaccu acuggaaggg aacgacagcg acaacgaccu uucccucgag      840

gacuucugag gacuaguacu ggcugcaucu cccuuuccuc uguccuccau ccuucuccca      900

ggauggugaa gggggaccug guacccagug auccccaccc caggauccua aaucaugacu      960

uaccugcuaa uaaaaacuca uuggaaaagu gagaagaucu aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     1080

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  1128


<210>  10726
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10726
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaguuugc uccugaauuc      120

cauggagaag augcaaacaa cagggcuacu aaauuccuag aaucaauaaa gggcaaauuc      180

acaucaccca aagaucccaa gaaaaaagau aguaucauau cugucaacuc aauagauaua      240

gaaguaacca aagaaagccc uauaacauca aauucaacua uuaucaaccc aacaaaugag      300

acagaugaua cugcagggaa caagcccaau uaucaaagaa aaccucuagu aaguuucaaa      360

gaagacccua caccaaguga uaaucccuuu ucuaaacuau acaaagaaac cauagaaaca      420

uuugauaaca augaagaaga auccagcuau ucauacgaag aaauaaauga ucagacaaac      480

gauaauauaa cagcaagauu agauaggauu gaugaaaaau uaagugaaau acuaggaaug      540

cuucacacau uaguaguggc aagugcagga ccuacaucug cucgggaugg uauaagagau      600

gccaugauug guuuaagaga agaaaugaua gaaaaaauca gaacugaagc auuaaugacc      660

aaugacagau uagaagcuau ggcaagacuc aggaaugagg aaagugaaaa gauggcaaaa      720

gacacaucag augaaguguc ucucaaucca acaucagaga aauugaacaa ccuauuggaa      780

gggaaugaua gugacaauga ucuaucacuu gaagauuucu gaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10727
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10727
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgcgacc aaguuccugg agagcaucaa ggggaaguuc      180

accuccccga aggaccccaa gaagaaggac agcaucaucu ccgugaacag caucgacauc      240

gaggucacga aggagucccc caucaccagc aacuccacca ucaucaaccc caccaacgag      300

acggacgaca ccgccggcaa caagccgaac uaccagcgga agccccucgu gagcuucaag      360

gaggacccca cccccuccga caacccguuc agcaagcugu acaaggagac caucgagacg      420

uucgacaaca acgaggagga guccagcuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu ggaccggauc gacgagaagc ucagcgagau ccuggggaug      540

cugcacaccc ucguggucgc cuccgccggc cccacgagcg cgcgcgacgg gauccgggac      600

gccaugaucg gccugcgcga ggagaugauc gagaagaucc ggaccgaggc ccugaugacc      660

aacgaccgcc ucgaggccau ggcgcggcug cgcaacgagg aguccgagaa gauggccaag      720

gacaccagcg acgagguguc ccugaacccc acgagcgaga agcucaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccucucccug gaggacuucu gaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10728
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10728
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgccacc aaguuccucg aguccaucaa gggcaaguuc      180

accuccccca aggaccccaa gaagaaggac uccaucaucu ccgucaacuc caucgacauc      240

gaggucacca aggagucccc caucaccucc aacuccacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagcgca agccccucgu cuccuucaag      360

gaggacccca cccccuccga caaccccuuc uccaagcucu acaaggagac caucgagacc      420

uucgacaaca acgaggagga guccuccuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu cgaccgcauc gacgagaagc ucuccgagau ccucggcaug      540

cuccacaccc ucgucgucgc cuccgccggc cccaccuccg cccgcgacgg cauccgcgac      600

gccaugaucg gccuccgcga ggagaugauc gagaagaucc gcaccgaggc ccucaugacc      660

aacgaccgcc ucgaggccau ggcccgccuc cgcaacgagg aguccgagaa gauggccaag      720

gacaccuccg acgaggucuc ccucaacccc accuccgaga agcucaacaa ccuccucgag      780

ggcaacgacu ccgacaacga ccucucccuc gaggacuucu gaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10729
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10729
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagcaacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauau cagugaacag uaucgauauu      240

gaggucacua aagaaagccc aaucacgucc aauucuacca uuaucaaccc cacaaaugag      300

acugacgaua ccgccggaaa caagccuaau uaccagagga aaccacucgu uucguucaag      360

gaggacccca caccuucaga uaacccauuu agcaaacuuu auaaggaaac cauagagacu      420

uucgacaaua acgaagagga gaguuccuac ucuuaugaag agaucaauga ucaaacaaac      480

gacaauauua ccgcgcggcu ggaucgcauc gacgaaaagu ugagcgagau uuuagguaug      540

cugcauacgc uagugguagc uuccgccggc cccacuucag cacgagaugg gauccgugac      600

gccaugauag gacucagaga agagaugauu gagaaaauca ggaccgaagc ucugaugaca      660

aacgaccggc uugaggcaau ggcccgccug agaaaugaag agagugaaaa gauggcuaaa      720

gauacuagcg acgagguguc uuugaacccu accuccgaga agcucaacaa ucugcuggaa      780

ggcaacgauu cagacaauga ucucagcuua gaggacuuuu gaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10730
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10730
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa cagagccacc aaguuccugg agagcaucaa gggcaaguuc      180

accagcccca aggaccccaa gaagaaggac agcaucauca gcgugaacag caucgacauc      240

gaggugacca aggagagccc caucaccagc aacagcacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagagaa agccccuggu gagcuucaag      360

gaggacccca cccccagcga caaccccuuc agcaagcugu acaaggagac caucgagacc      420

uucgacaaca acgaggagga gagcagcuac agcuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgccagacu ggacagaauc gacgagaagc ugagcgagau ccugggcaug      540

cugcacaccc uggugguggc cagcgccggc cccaccagcg ccagagacgg caucagagac      600

gccaugaucg gccugagaga ggagaugauc gagaagauca gaaccgaggc ccugaugacc      660

aacgacagac uggaggccau ggccagacug agaaacgagg agagcgagaa gauggccaag      720

gacaccagcg acgaggugag ccugaacccc accagcgaga agcugaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccugagccug gaggacuucu gaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10731
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10731
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagccacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauca gcgugaacuc cauugauauc      240

gaggucacga aagaaucucc cauuaccagc aauuccacaa ucaucaaccc uaccaaugag      300

acagacgaua ccgcgggaaa caagcccaau uaccagcgga aaccucucgu uucuuucaag      360

gaggacccca caccuagcga uaacccguuu uccaaacugu auaaggaaac cauugagacg      420

uucgacaaua acgaagagga gagcucuuac uccuaugaag agaucaauga ucaaaccaac      480

gacaauauua cagcucgccu ugauagaauc gacgaaaagc ugagcgagau ucucggcaug      540

cugcauaccc uugugguggc cucugccggg cccacauccg cucgggaugg aauccgcgac      600

gccaugauug gccugagaga agagaugauc gagaaaaucc ggaccgaagc ucucaugacg      660

aacgaccgcc uggaggccau ggcgagacug cggaaugaag agagcgaaaa gauggccaaa      720

gauacaucug acgaggucuc ccucaacccu accagcgaga agcugaacaa ucuucuggaa      780

gggaacgauu ccgacaauga ucucucucug gaggacuuuu gaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10732
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10732
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc accagaauuu      120

cacggagaag acgcaaacaa cagagcaaca aaauucuuag aaucaaucaa aggaaaauuc      180

acaagcccaa aagacccaaa aaaaaaagac ucaauaauaa gcguaaacuc aauagacaua      240

gaaguaacaa aagaaagccc aauaacaagc aacagcacaa uaauaaaccc aacaaacgaa      300

acagaugaca cagcuggaaa uaaaccaaac uaccaaagaa aaccccuagu cagcuucaaa      360

gaagacccca caccaucaga caacccauuc agcaaacuau auaaagaaac aauagaaaca      420

uuugacaaca acgaagaaga aucaucauac ucauacgaag aaauaaacga ccaaacaaac      480

gacaacauaa ccgcaagauu agacagaaua gaugaaaaac uaucagaaau acuaggaaug      540

cuacacacau uaguaguagc aagcgcagga ccaacaucag caagagacgg aauaagagac      600

gcaaugauag gacucagaga agaaaugaua gaaaaaauaa gaacagaagc acuaaugaca      660

aacgacagau uagaagcaau ggcaagacua agaaaugaag aaucggaaaa aauggcaaaa      720

gacacaucag acgaaguaag ccuaaaccca acaucagaaa aauuaaauaa ccuacuagaa      780

ggaaacgaca gcgacaacga cuuaucacua gaagacuucu aaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10733
<211>  1034
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10733
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc gcccgaguuc      120

cacggcgagg acgcgaacaa ccgcgcgaca aaguuccuag aaucaaucaa gggcaaauuc      180

acgagcccga aagaccccaa gaaaaaggac ucaaucauaa gcgugaacuc gaucgacauc      240

gaggucacga aagagagccc gaucacaagc aacagcacca uaauaaaccc gaccaacgaa      300

acagacgaca ccgcgggcaa caaaccgaac uaccaaagaa aaccgcucgu gagcuucaaa      360

gaagacccga ccccaagcga caacccguuc ucaaaacuau acaaggaaac gaucgagacc      420

uucgacaaca acgaggaaga gagcucguac ucguacgagg aaauaaacga ccaaacaaac      480

gacaacauaa ccgcacgccu agacaggauc gacgaaaaac ucucggaaau acucgggaug      540

cuacacacgc ucguggucgc gagcgcaggc ccgaccucgg ccagggacgg caucagggac      600

gcaaugauag gccugcgaga ggaaaugauc gagaaaauac gcaccgaagc acucaugacc      660

aacgacagac ucgaagccau ggccaggcuc aggaacgaag aauccgaaaa gauggcgaaa      720

gacaccucgg acgaggucuc gcucaacccc acgagcgaga aacugaacaa ccuacuggaa      780

gggaacgaca gcgacaacga ccuuucccuc gaggacuucu gaggacuagu guccaccugu      840

cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc agcgcuuuac      900

agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca     1020

gagccaccag aauu                                                       1034


<210>  10734
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10734
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aguuugcucc ugaauuccau ggagaagaug caaacaacag ggcuacuaaa      180

uuccuagaau caauaaaggg caaauucaca ucacccaaag aucccaagaa aaaagauagu      240

aucauaucug ucaacucaau agauauagaa guaaccaaag aaagcccuau aacaucaaau      300

ucaacuauua ucaacccaac aaaugagaca gaugauacug cagggaacaa gcccaauuau      360

caaagaaaac cucuaguaag uuucaaagaa gacccuacac caagugauaa ucccuuuucu      420

aaacuauaca aagaaaccau agaaacauuu gauaacaaug aagaagaauc cagcuauuca      480

uacgaagaaa uaaaugauca gacaaacgau aauauaacag caagauuaga uaggauugau      540

gaaaaauuaa gugaaauacu aggaaugcuu cacacauuag uaguggcaag ugcaggaccu      600

acaucugcuc gggaugguau aagagaugcc augauugguu uaagagaaga aaugauagaa      660

aaaaucagaa cugaagcauu aaugaccaau gacagauuag aagcuauggc aagacucagg      720

aaugaggaaa gugaaaagau ggcaaaagac acaucagaug aagugucucu caauccaaca      780

ucagagaaau ugaacaaccu auuggaaggg aaugauagug acaaugaucu aucacuugaa      840

gauuucugag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10735
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10735
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgcgaccaag      180

uuccuggaga gcaucaaggg gaaguucacc uccccgaagg accccaagaa gaaggacagc      240

aucaucuccg ugaacagcau cgacaucgag gucacgaagg agucccccau caccagcaac      300

uccaccauca ucaaccccac caacgagacg gacgacaccg ccggcaacaa gccgaacuac      360

cagcggaagc cccucgugag cuucaaggag gaccccaccc ccuccgacaa cccguucagc      420

aagcuguaca aggagaccau cgagacguuc gacaacaacg aggaggaguc cagcuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccugga ccggaucgac      540

gagaagcuca gcgagauccu ggggaugcug cacacccucg uggucgccuc cgccggcccc      600

acgagcgcgc gcgacgggau ccgggacgcc augaucggcc ugcgcgagga gaugaucgag      660

aagauccgga ccgaggcccu gaugaccaac gaccgccucg aggccauggc gcggcugcgc      720

aacgaggagu ccgagaagau ggccaaggac accagcgacg aggugucccu gaaccccacg      780

agcgagaagc ucaacaaccu gcuggagggc aacgacagcg acaacgaccu cucccuggag      840

gacuucugag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10736
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10736
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgccaccaag      180

uuccucgagu ccaucaaggg caaguucacc ucccccaagg accccaagaa gaaggacucc      240

aucaucuccg ucaacuccau cgacaucgag gucaccaagg agucccccau caccuccaac      300

uccaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagcgcaagc cccucgucuc cuucaaggag gaccccaccc ccuccgacaa ccccuucucc      420

aagcucuaca aggagaccau cgagaccuuc gacaacaacg aggaggaguc cuccuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccucga ccgcaucgac      540

gagaagcucu ccgagauccu cggcaugcuc cacacccucg ucgucgccuc cgccggcccc      600

accuccgccc gcgacggcau ccgcgacgcc augaucggcc uccgcgagga gaugaucgag      660

aagauccgca ccgaggcccu caugaccaac gaccgccucg aggccauggc ccgccuccgc      720

aacgaggagu ccgagaagau ggccaaggac accuccgacg aggucucccu caaccccacc      780

uccgagaagc ucaacaaccu ccucgagggc aacgacuccg acaacgaccu cucccucgag      840

gacuucugag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10737
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10737
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agcaaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuauaucag ugaacaguau cgauauugag gucacuaaag aaagcccaau cacguccaau      300

ucuaccauua ucaaccccac aaaugagacu gacgauaccg ccggaaacaa gccuaauuac      360

cagaggaaac cacucguuuc guucaaggag gaccccacac cuucagauaa cccauuuagc      420

aaacuuuaua aggaaaccau agagacuuuc gacaauaacg aagaggagag uuccuacucu      480

uaugaagaga ucaaugauca aacaaacgac aauauuaccg cgcggcugga ucgcaucgac      540

gaaaaguuga gcgagauuuu agguaugcug cauacgcuag ugguagcuuc cgccggcccc      600

acuucagcac gagaugggau ccgugacgcc augauaggac ucagagaaga gaugauugag      660

aaaaucagga ccgaagcucu gaugacaaac gaccggcuug aggcaauggc ccgccugaga      720

aaugaagaga gugaaaagau ggcuaaagau acuagcgacg aggugucuuu gaacccuacc      780

uccgagaagc ucaacaaucu gcuggaaggc aacgauucag acaaugaucu cagcuuagag      840

gacuuuugag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10738
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10738
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaacag agccaccaag      180

uuccuggaga gcaucaaggg caaguucacc agccccaagg accccaagaa gaaggacagc      240

aucaucagcg ugaacagcau cgacaucgag gugaccaagg agagccccau caccagcaac      300

agcaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagagaaagc cccuggugag cuucaaggag gaccccaccc ccagcgacaa ccccuucagc      420

aagcuguaca aggagaccau cgagaccuuc gacaacaacg aggaggagag cagcuacagc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg ccagacugga cagaaucgac      540

gagaagcuga gcgagauccu gggcaugcug cacacccugg ugguggccag cgccggcccc      600

accagcgcca gagacggcau cagagacgcc augaucggcc ugagagagga gaugaucgag      660

aagaucagaa ccgaggcccu gaugaccaac gacagacugg aggccauggc cagacugaga      720

aacgaggaga gcgagaagau ggccaaggac accagcgacg aggugagccu gaaccccacc      780

agcgagaagc ugaacaaccu gcuggagggc aacgacagcg acaacgaccu gagccuggag      840

gacuucugag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10739
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10739
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agccaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuaucagcg ugaacuccau ugauaucgag gucacgaaag aaucucccau uaccagcaau      300

uccacaauca ucaacccuac caaugagaca gacgauaccg cgggaaacaa gcccaauuac      360

cagcggaaac cucucguuuc uuucaaggag gaccccacac cuagcgauaa cccguuuucc      420

aaacuguaua aggaaaccau ugagacguuc gacaauaacg aagaggagag cucuuacucc      480

uaugaagaga ucaaugauca aaccaacgac aauauuacag cucgccuuga uagaaucgac      540

gaaaagcuga gcgagauucu cggcaugcug cauacccuug ugguggccuc ugccgggccc      600

acauccgcuc gggauggaau ccgcgacgcc augauuggcc ugagagaaga gaugaucgag      660

aaaauccgga ccgaagcucu caugacgaac gaccgccugg aggccauggc gagacugcgg      720

aaugaagaga gcgaaaagau ggccaaagau acaucugacg aggucucccu caacccuacc      780

agcgagaagc ugaacaaucu ucuggaaggg aacgauuccg acaaugaucu cucucuggag      840

gacuuuugag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10740
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10740
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcacc agaauuucac ggagaagacg caaacaacag agcaacaaaa      180

uucuuagaau caaucaaagg aaaauucaca agcccaaaag acccaaaaaa aaaagacuca      240

auaauaagcg uaaacucaau agacauagaa guaacaaaag aaagcccaau aacaagcaac      300

agcacaauaa uaaacccaac aaacgaaaca gaugacacag cuggaaauaa accaaacuac      360

caaagaaaac cccuagucag cuucaaagaa gaccccacac caucagacaa cccauucagc      420

aaacuauaua aagaaacaau agaaacauuu gacaacaacg aagaagaauc aucauacuca      480

uacgaagaaa uaaacgacca aacaaacgac aacauaaccg caagauuaga cagaauagau      540

gaaaaacuau cagaaauacu aggaaugcua cacacauuag uaguagcaag cgcaggacca      600

acaucagcaa gagacggaau aagagacgca augauaggac ucagagaaga aaugauagaa      660

aaaauaagaa cagaagcacu aaugacaaac gacagauuag aagcaauggc aagacuaaga      720

aaugaagaau cggaaaaaau ggcaaaagac acaucagacg aaguaagccu aaacccaaca      780

ucagaaaaau uaaauaaccu acuagaagga aacgacagcg acaacgacuu aucacuagaa      840

gacuucuaag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10741
<211>  1124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10741
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcgcc cgaguuccac ggcgaggacg cgaacaaccg cgcgacaaag      180

uuccuagaau caaucaaggg caaauucacg agcccgaaag accccaagaa aaaggacuca      240

aucauaagcg ugaacucgau cgacaucgag gucacgaaag agagcccgau cacaagcaac      300

agcaccauaa uaaacccgac caacgaaaca gacgacaccg cgggcaacaa accgaacuac      360

caaagaaaac cgcucgugag cuucaaagaa gacccgaccc caagcgacaa cccguucuca      420

aaacuauaca aggaaacgau cgagaccuuc gacaacaacg aggaagagag cucguacucg      480

uacgaggaaa uaaacgacca aacaaacgac aacauaaccg cacgccuaga caggaucgac      540

gaaaaacucu cggaaauacu cgggaugcua cacacgcucg uggucgcgag cgcaggcccg      600

accucggcca gggacggcau cagggacgca augauaggcc ugcgagagga aaugaucgag      660

aaaauacgca ccgaagcacu caugaccaac gacagacucg aagccauggc caggcucagg      720

aacgaagaau ccgaaaagau ggcgaaagac accucggacg aggucucgcu caaccccacg      780

agcgagaaac ugaacaaccu acuggaaggg aacgacagcg acaacgaccu uucccucgag      840

gacuucugag gacuagugga agcauuuucc uggcugauua aaagaaauua cucagcuaug      900

gucaucuguu ccuguuagaa ggcuaugcag cauauuauau acuaugcgca uguuaugaaa      960

ugcauaauaa aaaauuuuaa aaaaucuaaa agaucuaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc     1080

cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu                      1124


<210>  10742
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10742
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaguuugc uccugaauuc      120

cauggagaag augcaaacaa cagggcuacu aaauuccuag aaucaauaaa gggcaaauuc      180

acaucaccca aagaucccaa gaaaaaagau aguaucauau cugucaacuc aauagauaua      240

gaaguaacca aagaaagccc uauaacauca aauucaacua uuaucaaccc aacaaaugag      300

acagaugaua cugcagggaa caagcccaau uaucaaagaa aaccucuagu aaguuucaaa      360

gaagacccua caccaaguga uaaucccuuu ucuaaacuau acaaagaaac cauagaaaca      420

uuugauaaca augaagaaga auccagcuau ucauacgaag aaauaaauga ucagacaaac      480

gauaauauaa cagcaagauu agauaggauu gaugaaaaau uaagugaaau acuaggaaug      540

cuucacacau uaguaguggc aagugcagga ccuacaucug cucgggaugg uauaagagau      600

gccaugauug guuuaagaga agaaaugaua gaaaaaauca gaacugaagc auuaaugacc      660

aaugacagau uagaagcuau ggcaagacuc aggaaugagg aaagugaaaa gauggcaaaa      720

gacacaucag augaaguguc ucucaaucca acaucagaga aauugaacaa ccuauuggaa      780

gggaaugaua gugacaauga ucuaucacuu gaagauuucu gaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10743
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10743
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgcgacc aaguuccugg agagcaucaa ggggaaguuc      180

accuccccga aggaccccaa gaagaaggac agcaucaucu ccgugaacag caucgacauc      240

gaggucacga aggagucccc caucaccagc aacuccacca ucaucaaccc caccaacgag      300

acggacgaca ccgccggcaa caagccgaac uaccagcgga agccccucgu gagcuucaag      360

gaggacccca cccccuccga caacccguuc agcaagcugu acaaggagac caucgagacg      420

uucgacaaca acgaggagga guccagcuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu ggaccggauc gacgagaagc ucagcgagau ccuggggaug      540

cugcacaccc ucguggucgc cuccgccggc cccacgagcg cgcgcgacgg gauccgggac      600

gccaugaucg gccugcgcga ggagaugauc gagaagaucc ggaccgaggc ccugaugacc      660

aacgaccgcc ucgaggccau ggcgcggcug cgcaacgagg aguccgagaa gauggccaag      720

gacaccagcg acgagguguc ccugaacccc acgagcgaga agcucaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccucucccug gaggacuucu gaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10744
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10744
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgccacc aaguuccucg aguccaucaa gggcaaguuc      180

accuccccca aggaccccaa gaagaaggac uccaucaucu ccgucaacuc caucgacauc      240

gaggucacca aggagucccc caucaccucc aacuccacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagcgca agccccucgu cuccuucaag      360

gaggacccca cccccuccga caaccccuuc uccaagcucu acaaggagac caucgagacc      420

uucgacaaca acgaggagga guccuccuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu cgaccgcauc gacgagaagc ucuccgagau ccucggcaug      540

cuccacaccc ucgucgucgc cuccgccggc cccaccuccg cccgcgacgg cauccgcgac      600

gccaugaucg gccuccgcga ggagaugauc gagaagaucc gcaccgaggc ccucaugacc      660

aacgaccgcc ucgaggccau ggcccgccuc cgcaacgagg aguccgagaa gauggccaag      720

gacaccuccg acgaggucuc ccucaacccc accuccgaga agcucaacaa ccuccucgag      780

ggcaacgacu ccgacaacga ccucucccuc gaggacuucu gaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10745
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10745
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagcaacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauau cagugaacag uaucgauauu      240

gaggucacua aagaaagccc aaucacgucc aauucuacca uuaucaaccc cacaaaugag      300

acugacgaua ccgccggaaa caagccuaau uaccagagga aaccacucgu uucguucaag      360

gaggacccca caccuucaga uaacccauuu agcaaacuuu auaaggaaac cauagagacu      420

uucgacaaua acgaagagga gaguuccuac ucuuaugaag agaucaauga ucaaacaaac      480

gacaauauua ccgcgcggcu ggaucgcauc gacgaaaagu ugagcgagau uuuagguaug      540

cugcauacgc uagugguagc uuccgccggc cccacuucag cacgagaugg gauccgugac      600

gccaugauag gacucagaga agagaugauu gagaaaauca ggaccgaagc ucugaugaca      660

aacgaccggc uugaggcaau ggcccgccug agaaaugaag agagugaaaa gauggcuaaa      720

gauacuagcg acgagguguc uuugaacccu accuccgaga agcucaacaa ucugcuggaa      780

ggcaacgauu cagacaauga ucucagcuua gaggacuuuu gaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10746
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10746
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa cagagccacc aaguuccugg agagcaucaa gggcaaguuc      180

accagcccca aggaccccaa gaagaaggac agcaucauca gcgugaacag caucgacauc      240

gaggugacca aggagagccc caucaccagc aacagcacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagagaa agccccuggu gagcuucaag      360

gaggacccca cccccagcga caaccccuuc agcaagcugu acaaggagac caucgagacc      420

uucgacaaca acgaggagga gagcagcuac agcuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgccagacu ggacagaauc gacgagaagc ugagcgagau ccugggcaug      540

cugcacaccc uggugguggc cagcgccggc cccaccagcg ccagagacgg caucagagac      600

gccaugaucg gccugagaga ggagaugauc gagaagauca gaaccgaggc ccugaugacc      660

aacgacagac uggaggccau ggccagacug agaaacgagg agagcgagaa gauggccaag      720

gacaccagcg acgaggugag ccugaacccc accagcgaga agcugaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccugagccug gaggacuucu gaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10747
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10747
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagccacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauca gcgugaacuc cauugauauc      240

gaggucacga aagaaucucc cauuaccagc aauuccacaa ucaucaaccc uaccaaugag      300

acagacgaua ccgcgggaaa caagcccaau uaccagcgga aaccucucgu uucuuucaag      360

gaggacccca caccuagcga uaacccguuu uccaaacugu auaaggaaac cauugagacg      420

uucgacaaua acgaagagga gagcucuuac uccuaugaag agaucaauga ucaaaccaac      480

gacaauauua cagcucgccu ugauagaauc gacgaaaagc ugagcgagau ucucggcaug      540

cugcauaccc uugugguggc cucugccggg cccacauccg cucgggaugg aauccgcgac      600

gccaugauug gccugagaga agagaugauc gagaaaaucc ggaccgaagc ucucaugacg      660

aacgaccgcc uggaggccau ggcgagacug cggaaugaag agagcgaaaa gauggccaaa      720

gauacaucug acgaggucuc ccucaacccu accagcgaga agcugaacaa ucuucuggaa      780

gggaacgauu ccgacaauga ucucucucug gaggacuuuu gaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10748
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10748
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc accagaauuu      120

cacggagaag acgcaaacaa cagagcaaca aaauucuuag aaucaaucaa aggaaaauuc      180

acaagcccaa aagacccaaa aaaaaaagac ucaauaauaa gcguaaacuc aauagacaua      240

gaaguaacaa aagaaagccc aauaacaagc aacagcacaa uaauaaaccc aacaaacgaa      300

acagaugaca cagcuggaaa uaaaccaaac uaccaaagaa aaccccuagu cagcuucaaa      360

gaagacccca caccaucaga caacccauuc agcaaacuau auaaagaaac aauagaaaca      420

uuugacaaca acgaagaaga aucaucauac ucauacgaag aaauaaacga ccaaacaaac      480

gacaacauaa ccgcaagauu agacagaaua gaugaaaaac uaucagaaau acuaggaaug      540

cuacacacau uaguaguagc aagcgcagga ccaacaucag caagagacgg aauaagagac      600

gcaaugauag gacucagaga agaaaugaua gaaaaaauaa gaacagaagc acuaaugaca      660

aacgacagau uagaagcaau ggcaagacua agaaaugaag aaucggaaaa aauggcaaaa      720

gacacaucag acgaaguaag ccuaaaccca acaucagaaa aauuaaauaa ccuacuagaa      780

ggaaacgaca gcgacaacga cuuaucacua gaagacuucu aaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10749
<211>  1101
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10749
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc gcccgaguuc      120

cacggcgagg acgcgaacaa ccgcgcgaca aaguuccuag aaucaaucaa gggcaaauuc      180

acgagcccga aagaccccaa gaaaaaggac ucaaucauaa gcgugaacuc gaucgacauc      240

gaggucacga aagagagccc gaucacaagc aacagcacca uaauaaaccc gaccaacgaa      300

acagacgaca ccgcgggcaa caaaccgaac uaccaaagaa aaccgcucgu gagcuucaaa      360

gaagacccga ccccaagcga caacccguuc ucaaaacuau acaaggaaac gaucgagacc      420

uucgacaaca acgaggaaga gagcucguac ucguacgagg aaauaaacga ccaaacaaac      480

gacaacauaa ccgcacgccu agacaggauc gacgaaaaac ucucggaaau acucgggaug      540

cuacacacgc ucguggucgc gagcgcaggc ccgaccucgg ccagggacgg caucagggac      600

gcaaugauag gccugcgaga ggaaaugauc gagaaaauac gcaccgaagc acucaugacc      660

aacgacagac ucgaagccau ggccaggcuc aggaacgaag aauccgaaaa gauggcgaaa      720

gacaccucgg acgaggucuc gcucaacccc acgagcgaga aacugaacaa ccuacuggaa      780

gggaacgaca gcgacaacga ccuuucccuc gaggacuucu gaggacuagu acuggcugca      840

ucucccuuuc cucuguccuc cauccuucuc ccaggauggu gaagggggac cugguaccca      900

gugaucccca ccccaggauc cuaaaucaug acuuaccugc uaauaaaaac ucauuggaaa      960

agugagaaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1080

cuuuucagag ccaccagaau u                                               1101


<210>  10750
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10750
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaguuugc uccugaauuc      120

cauggagaag augcaaacaa cagggcuacu aaauuccuag aaucaauaaa gggcaaauuc      180

acaucaccca aagaucccaa gaaaaaagau aguaucauau cugucaacuc aauagauaua      240

gaaguaacca aagaaagccc uauaacauca aauucaacua uuaucaaccc aacaaaugag      300

acagaugaua cugcagggaa caagcccaau uaucaaagaa aaccucuagu aaguuucaaa      360

gaagacccua caccaaguga uaaucccuuu ucuaaacuau acaaagaaac cauagaaaca      420

uuugauaaca augaagaaga auccagcuau ucauacgaag aaauaaauga ucagacaaac      480

gauaauauaa cagcaagauu agauaggauu gaugaaaaau uaagugaaau acuaggaaug      540

cuucacacau uaguaguggc aagugcagga ccuacaucug cucgggaugg uauaagagau      600

gccaugauug guuuaagaga agaaaugaua gaaaaaauca gaacugaagc auuaaugacc      660

aaugacagau uagaagcuau ggcaagacuc aggaaugagg aaagugaaaa gauggcaaaa      720

gacacaucag augaaguguc ucucaaucca acaucagaga aauugaacaa ccuauuggaa      780

gggaaugaua gugacaauga ucuaucacuu gaagauuucu gaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10751
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10751
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgcgacc aaguuccugg agagcaucaa ggggaaguuc      180

accuccccga aggaccccaa gaagaaggac agcaucaucu ccgugaacag caucgacauc      240

gaggucacga aggagucccc caucaccagc aacuccacca ucaucaaccc caccaacgag      300

acggacgaca ccgccggcaa caagccgaac uaccagcgga agccccucgu gagcuucaag      360

gaggacccca cccccuccga caacccguuc agcaagcugu acaaggagac caucgagacg      420

uucgacaaca acgaggagga guccagcuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu ggaccggauc gacgagaagc ucagcgagau ccuggggaug      540

cugcacaccc ucguggucgc cuccgccggc cccacgagcg cgcgcgacgg gauccgggac      600

gccaugaucg gccugcgcga ggagaugauc gagaagaucc ggaccgaggc ccugaugacc      660

aacgaccgcc ucgaggccau ggcgcggcug cgcaacgagg aguccgagaa gauggccaag      720

gacaccagcg acgagguguc ccugaacccc acgagcgaga agcucaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccucucccug gaggacuucu gaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10752
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10752
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgccacc aaguuccucg aguccaucaa gggcaaguuc      180

accuccccca aggaccccaa gaagaaggac uccaucaucu ccgucaacuc caucgacauc      240

gaggucacca aggagucccc caucaccucc aacuccacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagcgca agccccucgu cuccuucaag      360

gaggacccca cccccuccga caaccccuuc uccaagcucu acaaggagac caucgagacc      420

uucgacaaca acgaggagga guccuccuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu cgaccgcauc gacgagaagc ucuccgagau ccucggcaug      540

cuccacaccc ucgucgucgc cuccgccggc cccaccuccg cccgcgacgg cauccgcgac      600

gccaugaucg gccuccgcga ggagaugauc gagaagaucc gcaccgaggc ccucaugacc      660

aacgaccgcc ucgaggccau ggcccgccuc cgcaacgagg aguccgagaa gauggccaag      720

gacaccuccg acgaggucuc ccucaacccc accuccgaga agcucaacaa ccuccucgag      780

ggcaacgacu ccgacaacga ccucucccuc gaggacuucu gaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10753
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10753
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagcaacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauau cagugaacag uaucgauauu      240

gaggucacua aagaaagccc aaucacgucc aauucuacca uuaucaaccc cacaaaugag      300

acugacgaua ccgccggaaa caagccuaau uaccagagga aaccacucgu uucguucaag      360

gaggacccca caccuucaga uaacccauuu agcaaacuuu auaaggaaac cauagagacu      420

uucgacaaua acgaagagga gaguuccuac ucuuaugaag agaucaauga ucaaacaaac      480

gacaauauua ccgcgcggcu ggaucgcauc gacgaaaagu ugagcgagau uuuagguaug      540

cugcauacgc uagugguagc uuccgccggc cccacuucag cacgagaugg gauccgugac      600

gccaugauag gacucagaga agagaugauu gagaaaauca ggaccgaagc ucugaugaca      660

aacgaccggc uugaggcaau ggcccgccug agaaaugaag agagugaaaa gauggcuaaa      720

gauacuagcg acgagguguc uuugaacccu accuccgaga agcucaacaa ucugcuggaa      780

ggcaacgauu cagacaauga ucucagcuua gaggacuuuu gaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10754
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10754
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa cagagccacc aaguuccugg agagcaucaa gggcaaguuc      180

accagcccca aggaccccaa gaagaaggac agcaucauca gcgugaacag caucgacauc      240

gaggugacca aggagagccc caucaccagc aacagcacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagagaa agccccuggu gagcuucaag      360

gaggacccca cccccagcga caaccccuuc agcaagcugu acaaggagac caucgagacc      420

uucgacaaca acgaggagga gagcagcuac agcuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgccagacu ggacagaauc gacgagaagc ugagcgagau ccugggcaug      540

cugcacaccc uggugguggc cagcgccggc cccaccagcg ccagagacgg caucagagac      600

gccaugaucg gccugagaga ggagaugauc gagaagauca gaaccgaggc ccugaugacc      660

aacgacagac uggaggccau ggccagacug agaaacgagg agagcgagaa gauggccaag      720

gacaccagcg acgaggugag ccugaacccc accagcgaga agcugaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccugagccug gaggacuucu gaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10755
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10755
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagccacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauca gcgugaacuc cauugauauc      240

gaggucacga aagaaucucc cauuaccagc aauuccacaa ucaucaaccc uaccaaugag      300

acagacgaua ccgcgggaaa caagcccaau uaccagcgga aaccucucgu uucuuucaag      360

gaggacccca caccuagcga uaacccguuu uccaaacugu auaaggaaac cauugagacg      420

uucgacaaua acgaagagga gagcucuuac uccuaugaag agaucaauga ucaaaccaac      480

gacaauauua cagcucgccu ugauagaauc gacgaaaagc ugagcgagau ucucggcaug      540

cugcauaccc uugugguggc cucugccggg cccacauccg cucgggaugg aauccgcgac      600

gccaugauug gccugagaga agagaugauc gagaaaaucc ggaccgaagc ucucaugacg      660

aacgaccgcc uggaggccau ggcgagacug cggaaugaag agagcgaaaa gauggccaaa      720

gauacaucug acgaggucuc ccucaacccu accagcgaga agcugaacaa ucuucuggaa      780

gggaacgauu ccgacaauga ucucucucug gaggacuuuu gaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10756
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10756
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc accagaauuu      120

cacggagaag acgcaaacaa cagagcaaca aaauucuuag aaucaaucaa aggaaaauuc      180

acaagcccaa aagacccaaa aaaaaaagac ucaauaauaa gcguaaacuc aauagacaua      240

gaaguaacaa aagaaagccc aauaacaagc aacagcacaa uaauaaaccc aacaaacgaa      300

acagaugaca cagcuggaaa uaaaccaaac uaccaaagaa aaccccuagu cagcuucaaa      360

gaagacccca caccaucaga caacccauuc agcaaacuau auaaagaaac aauagaaaca      420

uuugacaaca acgaagaaga aucaucauac ucauacgaag aaauaaacga ccaaacaaac      480

gacaacauaa ccgcaagauu agacagaaua gaugaaaaac uaucagaaau acuaggaaug      540

cuacacacau uaguaguagc aagcgcagga ccaacaucag caagagacgg aauaagagac      600

gcaaugauag gacucagaga agaaaugaua gaaaaaauaa gaacagaagc acuaaugaca      660

aacgacagau uagaagcaau ggcaagacua agaaaugaag aaucggaaaa aauggcaaaa      720

gacacaucag acgaaguaag ccuaaaccca acaucagaaa aauuaaauaa ccuacuagaa      780

ggaaacgaca gcgacaacga cuuaucacua gaagacuucu aaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10757
<211>  1097
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10757
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc gcccgaguuc      120

cacggcgagg acgcgaacaa ccgcgcgaca aaguuccuag aaucaaucaa gggcaaauuc      180

acgagcccga aagaccccaa gaaaaaggac ucaaucauaa gcgugaacuc gaucgacauc      240

gaggucacga aagagagccc gaucacaagc aacagcacca uaauaaaccc gaccaacgaa      300

acagacgaca ccgcgggcaa caaaccgaac uaccaaagaa aaccgcucgu gagcuucaaa      360

gaagacccga ccccaagcga caacccguuc ucaaaacuau acaaggaaac gaucgagacc      420

uucgacaaca acgaggaaga gagcucguac ucguacgagg aaauaaacga ccaaacaaac      480

gacaacauaa ccgcacgccu agacaggauc gacgaaaaac ucucggaaau acucgggaug      540

cuacacacgc ucguggucgc gagcgcaggc ccgaccucgg ccagggacgg caucagggac      600

gcaaugauag gccugcgaga ggaaaugauc gagaaaauac gcaccgaagc acucaugacc      660

aacgacagac ucgaagccau ggccaggcuc aggaacgaag aauccgaaaa gauggcgaaa      720

gacaccucgg acgaggucuc gcucaacccc acgagcgaga aacugaacaa ccuacuggaa      780

gggaacgaca gcgacaacga ccuuucccuc gaggacuucu gaggacuagu ggaagcauuu      840

uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua gaaggcuaug      900

cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu uaaaaaaucu      960

aaaagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1080

ucagagccac cagaauu                                                    1097


<210>  10758
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10758
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaagu uugcuccuga auuccaugga      120

gaagaugcaa acaacagggc uacuaaauuc cuagaaucaa uaaagggcaa auucacauca      180

cccaaagauc ccaagaaaaa agauaguauc auaucuguca acucaauaga uauagaagua      240

accaaagaaa gcccuauaac aucaaauuca acuauuauca acccaacaaa ugagacagau      300

gauacugcag ggaacaagcc caauuaucaa agaaaaccuc uaguaaguuu caaagaagac      360

ccuacaccaa gugauaaucc cuuuucuaaa cuauacaaag aaaccauaga aacauuugau      420

aacaaugaag aagaauccag cuauucauac gaagaaauaa augaucagac aaacgauaau      480

auaacagcaa gauuagauag gauugaugaa aaauuaagug aaauacuagg aaugcuucac      540

acauuaguag uggcaagugc aggaccuaca ucugcucggg augguauaag agaugccaug      600

auugguuuaa gagaagaaau gauagaaaaa aucagaacug aagcauuaau gaccaaugac      660

agauuagaag cuauggcaag acucaggaau gaggaaagug aaaagauggc aaaagacaca      720

ucagaugaag ugucucucaa uccaacauca gagaaauuga acaaccuauu ggaagggaau      780

gauagugaca augaucuauc acuugaagau uucugaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10759
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10759
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc gaccaaguuc cuggagagca ucaaggggaa guucaccucc      180

ccgaaggacc ccaagaagaa ggacagcauc aucuccguga acagcaucga caucgagguc      240

acgaaggagu cccccaucac cagcaacucc accaucauca accccaccaa cgagacggac      300

gacaccgccg gcaacaagcc gaacuaccag cggaagcccc ucgugagcuu caaggaggac      360

cccacccccu ccgacaaccc guucagcaag cuguacaagg agaccaucga gacguucgac      420

aacaacgagg aggaguccag cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccuggaccg gaucgacgag aagcucagcg agauccuggg gaugcugcac      540

acccucgugg ucgccuccgc cggccccacg agcgcgcgcg acgggauccg ggacgccaug      600

aucggccugc gcgaggagau gaucgagaag auccggaccg aggcccugau gaccaacgac      660

cgccucgagg ccauggcgcg gcugcgcaac gaggaguccg agaagauggc caaggacacc      720

agcgacgagg ugucccugaa ccccacgagc gagaagcuca acaaccugcu ggagggcaac      780

gacagcgaca acgaccucuc ccuggaggac uucugaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10760
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10760
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc caccaaguuc cucgagucca ucaagggcaa guucaccucc      180

cccaaggacc ccaagaagaa ggacuccauc aucuccguca acuccaucga caucgagguc      240

accaaggagu cccccaucac cuccaacucc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag cgcaagcccc ucgucuccuu caaggaggac      360

cccacccccu ccgacaaccc cuucuccaag cucuacaagg agaccaucga gaccuucgac      420

aacaacgagg aggaguccuc cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccucgaccg caucgacgag aagcucuccg agauccucgg caugcuccac      540

acccucgucg ucgccuccgc cggccccacc uccgcccgcg acggcauccg cgacgccaug      600

aucggccucc gcgaggagau gaucgagaag auccgcaccg aggcccucau gaccaacgac      660

cgccucgagg ccauggcccg ccuccgcaac gaggaguccg agaagauggc caaggacacc      720

uccgacgagg ucucccucaa ccccaccucc gagaagcuca acaaccuccu cgagggcaac      780

gacuccgaca acgaccucuc ccucgaggac uucugaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10761
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10761
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc aaccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu auaucaguga acaguaucga uauugagguc      240

acuaaagaaa gcccaaucac guccaauucu accauuauca accccacaaa ugagacugac      300

gauaccgccg gaaacaagcc uaauuaccag aggaaaccac ucguuucguu caaggaggac      360

cccacaccuu cagauaaccc auuuagcaaa cuuuauaagg aaaccauaga gacuuucgac      420

aauaacgaag aggagaguuc cuacucuuau gaagagauca augaucaaac aaacgacaau      480

auuaccgcgc ggcuggaucg caucgacgaa aaguugagcg agauuuuagg uaugcugcau      540

acgcuagugg uagcuuccgc cggccccacu ucagcacgag augggauccg ugacgccaug      600

auaggacuca gagaagagau gauugagaaa aucaggaccg aagcucugau gacaaacgac      660

cggcuugagg caauggcccg ccugagaaau gaagagagug aaaagauggc uaaagauacu      720

agcgacgagg ugucuuugaa cccuaccucc gagaagcuca acaaucugcu ggaaggcaac      780

gauucagaca augaucucag cuuagaggac uuuugaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10762
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10762
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaacagagc caccaaguuc cuggagagca ucaagggcaa guucaccagc      180

cccaaggacc ccaagaagaa ggacagcauc aucagcguga acagcaucga caucgaggug      240

accaaggaga gccccaucac cagcaacagc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag agaaagcccc uggugagcuu caaggaggac      360

cccaccccca gcgacaaccc cuucagcaag cuguacaagg agaccaucga gaccuucgac      420

aacaacgagg aggagagcag cuacagcuac gaggagauca acgaccagac caacgacaac      480

aucaccgcca gacuggacag aaucgacgag aagcugagcg agauccuggg caugcugcac      540

acccuggugg uggccagcgc cggccccacc agcgccagag acggcaucag agacgccaug      600

aucggccuga gagaggagau gaucgagaag aucagaaccg aggcccugau gaccaacgac      660

agacuggagg ccauggccag acugagaaac gaggagagcg agaagauggc caaggacacc      720

agcgacgagg ugagccugaa ccccaccagc gagaagcuga acaaccugcu ggagggcaac      780

gacagcgaca acgaccugag ccuggaggac uucugaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10763
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10763
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc caccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu aucagcguga acuccauuga uaucgagguc      240

acgaaagaau cucccauuac cagcaauucc acaaucauca acccuaccaa ugagacagac      300

gauaccgcgg gaaacaagcc caauuaccag cggaaaccuc ucguuucuuu caaggaggac      360

cccacaccua gcgauaaccc guuuuccaaa cuguauaagg aaaccauuga gacguucgac      420

aauaacgaag aggagagcuc uuacuccuau gaagagauca augaucaaac caacgacaau      480

auuacagcuc gccuugauag aaucgacgaa aagcugagcg agauucucgg caugcugcau      540

acccuugugg uggccucugc cgggcccaca uccgcucggg auggaauccg cgacgccaug      600

auuggccuga gagaagagau gaucgagaaa auccggaccg aagcucucau gacgaacgac      660

cgccuggagg ccauggcgag acugcggaau gaagagagcg aaaagauggc caaagauaca      720

ucugacgagg ucucccucaa cccuaccagc gagaagcuga acaaucuucu ggaagggaac      780

gauuccgaca augaucucuc ucuggaggac uuuugaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10764
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10764
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcaccaga auuucacgga      120

gaagacgcaa acaacagagc aacaaaauuc uuagaaucaa ucaaaggaaa auucacaagc      180

ccaaaagacc caaaaaaaaa agacucaaua auaagcguaa acucaauaga cauagaagua      240

acaaaagaaa gcccaauaac aagcaacagc acaauaauaa acccaacaaa cgaaacagau      300

gacacagcug gaaauaaacc aaacuaccaa agaaaacccc uagucagcuu caaagaagac      360

cccacaccau cagacaaccc auucagcaaa cuauauaaag aaacaauaga aacauuugac      420

aacaacgaag aagaaucauc auacucauac gaagaaauaa acgaccaaac aaacgacaac      480

auaaccgcaa gauuagacag aauagaugaa aaacuaucag aaauacuagg aaugcuacac      540

acauuaguag uagcaagcgc aggaccaaca ucagcaagag acggaauaag agacgcaaug      600

auaggacuca gagaagaaau gauagaaaaa auaagaacag aagcacuaau gacaaacgac      660

agauuagaag caauggcaag acuaagaaau gaagaaucgg aaaaaauggc aaaagacaca      720

ucagacgaag uaagccuaaa cccaacauca gaaaaauuaa auaaccuacu agaaggaaac      780

gacagcgaca acgacuuauc acuagaagac uucuaaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10765
<211>  1015
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design c-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10765
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcgcccga guuccacggc      120

gaggacgcga acaaccgcgc gacaaaguuc cuagaaucaa ucaagggcaa auucacgagc      180

ccgaaagacc ccaagaaaaa ggacucaauc auaagcguga acucgaucga caucgagguc      240

acgaaagaga gcccgaucac aagcaacagc accauaauaa acccgaccaa cgaaacagac      300

gacaccgcgg gcaacaaacc gaacuaccaa agaaaaccgc ucgugagcuu caaagaagac      360

ccgaccccaa gcgacaaccc guucucaaaa cuauacaagg aaacgaucga gaccuucgac      420

aacaacgagg aagagagcuc guacucguac gaggaaauaa acgaccaaac aaacgacaac      480

auaaccgcac gccuagacag gaucgacgaa aaacucucgg aaauacucgg gaugcuacac      540

acgcucgugg ucgcgagcgc aggcccgacc ucggccaggg acggcaucag ggacgcaaug      600

auaggccugc gagaggaaau gaucgagaaa auacgcaccg aagcacucau gaccaacgac      660

agacucgaag ccauggccag gcucaggaac gaagaauccg aaaagauggc gaaagacacc      720

ucggacgagg ucucgcucaa ccccacgagc gagaaacuga acaaccuacu ggaagggaac      780

gacagcgaca acgaccuuuc ccucgaggac uucugaggac uagucccugu ucccagagcc      840

cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      960

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1015


<210>  10766
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10766
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaguu ugcuccugaa      120

uuccauggag aagaugcaaa caacagggcu acuaaauucc uagaaucaau aaagggcaaa      180

uucacaucac ccaaagaucc caagaaaaaa gauaguauca uaucugucaa cucaauagau      240

auagaaguaa ccaaagaaag cccuauaaca ucaaauucaa cuauuaucaa cccaacaaau      300

gagacagaug auacugcagg gaacaagccc aauuaucaaa gaaaaccucu aguaaguuuc      360

aaagaagacc cuacaccaag ugauaauccc uuuucuaaac uauacaaaga aaccauagaa      420

acauuugaua acaaugaaga agaauccagc uauucauacg aagaaauaaa ugaucagaca      480

aacgauaaua uaacagcaag auuagauagg auugaugaaa aauuaaguga aauacuagga      540

augcuucaca cauuaguagu ggcaagugca ggaccuacau cugcucggga ugguauaaga      600

gaugccauga uugguuuaag agaagaaaug auagaaaaaa ucagaacuga agcauuaaug      660

accaaugaca gauuagaagc uauggcaaga cucaggaaug aggaaaguga aaagauggca      720

aaagacacau cagaugaagu gucucucaau ccaacaucag agaaauugaa caaccuauug      780

gaagggaaug auagugacaa ugaucuauca cuugaagauu ucugaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10767
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10767
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcg accaaguucc uggagagcau caaggggaag      180

uucaccuccc cgaaggaccc caagaagaag gacagcauca ucuccgugaa cagcaucgac      240

aucgagguca cgaaggaguc ccccaucacc agcaacucca ccaucaucaa ccccaccaac      300

gagacggacg acaccgccgg caacaagccg aacuaccagc ggaagccccu cgugagcuuc      360

aaggaggacc ccacccccuc cgacaacccg uucagcaagc uguacaagga gaccaucgag      420

acguucgaca acaacgagga ggaguccagc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccuggaccgg aucgacgaga agcucagcga gauccugggg      540

augcugcaca cccucguggu cgccuccgcc ggccccacga gcgcgcgcga cgggauccgg      600

gacgccauga ucggccugcg cgaggagaug aucgagaaga uccggaccga ggcccugaug      660

accaacgacc gccucgaggc cauggcgcgg cugcgcaacg aggaguccga gaagauggcc      720

aaggacacca gcgacgaggu gucccugaac cccacgagcg agaagcucaa caaccugcug      780

gagggcaacg acagcgacaa cgaccucucc cuggaggacu ucugaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10768
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10768
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcc accaaguucc ucgaguccau caagggcaag      180

uucaccuccc ccaaggaccc caagaagaag gacuccauca ucuccgucaa cuccaucgac      240

aucgagguca ccaaggaguc ccccaucacc uccaacucca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccagc gcaagccccu cgucuccuuc      360

aaggaggacc ccacccccuc cgacaacccc uucuccaagc ucuacaagga gaccaucgag      420

accuucgaca acaacgagga ggaguccucc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccucgaccgc aucgacgaga agcucuccga gauccucggc      540

augcuccaca cccucgucgu cgccuccgcc ggccccaccu ccgcccgcga cggcauccgc      600

gacgccauga ucggccuccg cgaggagaug aucgagaaga uccgcaccga ggcccucaug      660

accaacgacc gccucgaggc cauggcccgc cuccgcaacg aggaguccga gaagauggcc      720

aaggacaccu ccgacgaggu cucccucaac cccaccuccg agaagcucaa caaccuccuc      780

gagggcaacg acuccgacaa cgaccucucc cucgaggacu ucugaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10769
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10769
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagca accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua uaucagugaa caguaucgau      240

auugagguca cuaaagaaag cccaaucacg uccaauucua ccauuaucaa ccccacaaau      300

gagacugacg auaccgccgg aaacaagccu aauuaccaga ggaaaccacu cguuucguuc      360

aaggaggacc ccacaccuuc agauaaccca uuuagcaaac uuuauaagga aaccauagag      420

acuuucgaca auaacgaaga ggagaguucc uacucuuaug aagagaucaa ugaucaaaca      480

aacgacaaua uuaccgcgcg gcuggaucgc aucgacgaaa aguugagcga gauuuuaggu      540

augcugcaua cgcuaguggu agcuuccgcc ggccccacuu cagcacgaga ugggauccgu      600

gacgccauga uaggacucag agaagagaug auugagaaaa ucaggaccga agcucugaug      660

acaaacgacc ggcuugaggc aauggcccgc cugagaaaug aagagaguga aaagauggcu      720

aaagauacua gcgacgaggu gucuuugaac ccuaccuccg agaagcucaa caaucugcug      780

gaaggcaacg auucagacaa ugaucucagc uuagaggacu uuugaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10770
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10770
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caacagagcc accaaguucc uggagagcau caagggcaag      180

uucaccagcc ccaaggaccc caagaagaag gacagcauca ucagcgugaa cagcaucgac      240

aucgagguga ccaaggagag ccccaucacc agcaacagca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccaga gaaagccccu ggugagcuuc      360

aaggaggacc ccacccccag cgacaacccc uucagcaagc uguacaagga gaccaucgag      420

accuucgaca acaacgagga ggagagcagc uacagcuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgccag acuggacaga aucgacgaga agcugagcga gauccugggc      540

augcugcaca cccugguggu ggccagcgcc ggccccacca gcgccagaga cggcaucaga      600

gacgccauga ucggccugag agaggagaug aucgagaaga ucagaaccga ggcccugaug      660

accaacgaca gacuggaggc cauggccaga cugagaaacg aggagagcga gaagauggcc      720

aaggacacca gcgacgaggu gagccugaac cccaccagcg agaagcugaa caaccugcug      780

gagggcaacg acagcgacaa cgaccugagc cuggaggacu ucugaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10771
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10771
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagcc accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua ucagcgugaa cuccauugau      240

aucgagguca cgaaagaauc ucccauuacc agcaauucca caaucaucaa cccuaccaau      300

gagacagacg auaccgcggg aaacaagccc aauuaccagc ggaaaccucu cguuucuuuc      360

aaggaggacc ccacaccuag cgauaacccg uuuuccaaac uguauaagga aaccauugag      420

acguucgaca auaacgaaga ggagagcucu uacuccuaug aagagaucaa ugaucaaacc      480

aacgacaaua uuacagcucg ccuugauaga aucgacgaaa agcugagcga gauucucggc      540

augcugcaua cccuuguggu ggccucugcc gggcccacau ccgcucggga uggaauccgc      600

gacgccauga uuggccugag agaagagaug aucgagaaaa uccggaccga agcucucaug      660

acgaacgacc gccuggaggc cauggcgaga cugcggaaug aagagagcga aaagauggcc      720

aaagauacau cugacgaggu cucccucaac ccuaccagcg agaagcugaa caaucuucug      780

gaagggaacg auuccgacaa ugaucucucu cuggaggacu uuugaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10772
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10772
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcaccagaa      120

uuucacggag aagacgcaaa caacagagca acaaaauucu uagaaucaau caaaggaaaa      180

uucacaagcc caaaagaccc aaaaaaaaaa gacucaauaa uaagcguaaa cucaauagac      240

auagaaguaa caaaagaaag cccaauaaca agcaacagca caauaauaaa cccaacaaac      300

gaaacagaug acacagcugg aaauaaacca aacuaccaaa gaaaaccccu agucagcuuc      360

aaagaagacc ccacaccauc agacaaccca uucagcaaac uauauaaaga aacaauagaa      420

acauuugaca acaacgaaga agaaucauca uacucauacg aagaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcaag auuagacaga auagaugaaa aacuaucaga aauacuagga      540

augcuacaca cauuaguagu agcaagcgca ggaccaacau cagcaagaga cggaauaaga      600

gacgcaauga uaggacucag agaagaaaug auagaaaaaa uaagaacaga agcacuaaug      660

acaaacgaca gauuagaagc aauggcaaga cuaagaaaug aagaaucgga aaaaauggca      720

aaagacacau cagacgaagu aagccuaaac ccaacaucag aaaaauuaaa uaaccuacua      780

gaaggaaacg acagcgacaa cgacuuauca cuagaagacu ucuaaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10773
<211>  1024
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10773
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcgcccgag      120

uuccacggcg aggacgcgaa caaccgcgcg acaaaguucc uagaaucaau caagggcaaa      180

uucacgagcc cgaaagaccc caagaaaaag gacucaauca uaagcgugaa cucgaucgac      240

aucgagguca cgaaagagag cccgaucaca agcaacagca ccauaauaaa cccgaccaac      300

gaaacagacg acaccgcggg caacaaaccg aacuaccaaa gaaaaccgcu cgugagcuuc      360

aaagaagacc cgaccccaag cgacaacccg uucucaaaac uauacaagga aacgaucgag      420

accuucgaca acaacgagga agagagcucg uacucguacg aggaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcacg ccuagacagg aucgacgaaa aacucucgga aauacucggg      540

augcuacaca cgcucguggu cgcgagcgca ggcccgaccu cggccaggga cggcaucagg      600

gacgcaauga uaggccugcg agaggaaaug aucgagaaaa uacgcaccga agcacucaug      660

accaacgaca gacucgaagc cauggccagg cucaggaacg aagaauccga aaagauggcg      720

aaagacaccu cggacgaggu cucgcucaac cccacgagcg agaaacugaa caaccuacug      780

gaagggaacg acagcgacaa cgaccuuucc cucgaggacu ucugaggacu agucccuguu      840

cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1020

aauu                                                                  1024


<210>  10774
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10774
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaagu uugcuccuga auuccaugga      120

gaagaugcaa acaacagggc uacuaaauuc cuagaaucaa uaaagggcaa auucacauca      180

cccaaagauc ccaagaaaaa agauaguauc auaucuguca acucaauaga uauagaagua      240

accaaagaaa gcccuauaac aucaaauuca acuauuauca acccaacaaa ugagacagau      300

gauacugcag ggaacaagcc caauuaucaa agaaaaccuc uaguaaguuu caaagaagac      360

ccuacaccaa gugauaaucc cuuuucuaaa cuauacaaag aaaccauaga aacauuugau      420

aacaaugaag aagaauccag cuauucauac gaagaaauaa augaucagac aaacgauaau      480

auaacagcaa gauuagauag gauugaugaa aaauuaagug aaauacuagg aaugcuucac      540

acauuaguag uggcaagugc aggaccuaca ucugcucggg augguauaag agaugccaug      600

auugguuuaa gagaagaaau gauagaaaaa aucagaacug aagcauuaau gaccaaugac      660

agauuagaag cuauggcaag acucaggaau gaggaaagug aaaagauggc aaaagacaca      720

ucagaugaag ugucucucaa uccaacauca gagaaauuga acaaccuauu ggaagggaau      780

gauagugaca augaucuauc acuugaagau uucugaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10775
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10775
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc gaccaaguuc cuggagagca ucaaggggaa guucaccucc      180

ccgaaggacc ccaagaagaa ggacagcauc aucuccguga acagcaucga caucgagguc      240

acgaaggagu cccccaucac cagcaacucc accaucauca accccaccaa cgagacggac      300

gacaccgccg gcaacaagcc gaacuaccag cggaagcccc ucgugagcuu caaggaggac      360

cccacccccu ccgacaaccc guucagcaag cuguacaagg agaccaucga gacguucgac      420

aacaacgagg aggaguccag cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccuggaccg gaucgacgag aagcucagcg agauccuggg gaugcugcac      540

acccucgugg ucgccuccgc cggccccacg agcgcgcgcg acgggauccg ggacgccaug      600

aucggccugc gcgaggagau gaucgagaag auccggaccg aggcccugau gaccaacgac      660

cgccucgagg ccauggcgcg gcugcgcaac gaggaguccg agaagauggc caaggacacc      720

agcgacgagg ugucccugaa ccccacgagc gagaagcuca acaaccugcu ggagggcaac      780

gacagcgaca acgaccucuc ccuggaggac uucugaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10776
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10776
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc caccaaguuc cucgagucca ucaagggcaa guucaccucc      180

cccaaggacc ccaagaagaa ggacuccauc aucuccguca acuccaucga caucgagguc      240

accaaggagu cccccaucac cuccaacucc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag cgcaagcccc ucgucuccuu caaggaggac      360

cccacccccu ccgacaaccc cuucuccaag cucuacaagg agaccaucga gaccuucgac      420

aacaacgagg aggaguccuc cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccucgaccg caucgacgag aagcucuccg agauccucgg caugcuccac      540

acccucgucg ucgccuccgc cggccccacc uccgcccgcg acggcauccg cgacgccaug      600

aucggccucc gcgaggagau gaucgagaag auccgcaccg aggcccucau gaccaacgac      660

cgccucgagg ccauggcccg ccuccgcaac gaggaguccg agaagauggc caaggacacc      720

uccgacgagg ucucccucaa ccccaccucc gagaagcuca acaaccuccu cgagggcaac      780

gacuccgaca acgaccucuc ccucgaggac uucugaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10777
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10777
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc aaccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu auaucaguga acaguaucga uauugagguc      240

acuaaagaaa gcccaaucac guccaauucu accauuauca accccacaaa ugagacugac      300

gauaccgccg gaaacaagcc uaauuaccag aggaaaccac ucguuucguu caaggaggac      360

cccacaccuu cagauaaccc auuuagcaaa cuuuauaagg aaaccauaga gacuuucgac      420

aauaacgaag aggagaguuc cuacucuuau gaagagauca augaucaaac aaacgacaau      480

auuaccgcgc ggcuggaucg caucgacgaa aaguugagcg agauuuuagg uaugcugcau      540

acgcuagugg uagcuuccgc cggccccacu ucagcacgag augggauccg ugacgccaug      600

auaggacuca gagaagagau gauugagaaa aucaggaccg aagcucugau gacaaacgac      660

cggcuugagg caauggcccg ccugagaaau gaagagagug aaaagauggc uaaagauacu      720

agcgacgagg ugucuuugaa cccuaccucc gagaagcuca acaaucugcu ggaaggcaac      780

gauucagaca augaucucag cuuagaggac uuuugaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10778
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10778
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaacagagc caccaaguuc cuggagagca ucaagggcaa guucaccagc      180

cccaaggacc ccaagaagaa ggacagcauc aucagcguga acagcaucga caucgaggug      240

accaaggaga gccccaucac cagcaacagc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag agaaagcccc uggugagcuu caaggaggac      360

cccaccccca gcgacaaccc cuucagcaag cuguacaagg agaccaucga gaccuucgac      420

aacaacgagg aggagagcag cuacagcuac gaggagauca acgaccagac caacgacaac      480

aucaccgcca gacuggacag aaucgacgag aagcugagcg agauccuggg caugcugcac      540

acccuggugg uggccagcgc cggccccacc agcgccagag acggcaucag agacgccaug      600

aucggccuga gagaggagau gaucgagaag aucagaaccg aggcccugau gaccaacgac      660

agacuggagg ccauggccag acugagaaac gaggagagcg agaagauggc caaggacacc      720

agcgacgagg ugagccugaa ccccaccagc gagaagcuga acaaccugcu ggagggcaac      780

gacagcgaca acgaccugag ccuggaggac uucugaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10779
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10779
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc caccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu aucagcguga acuccauuga uaucgagguc      240

acgaaagaau cucccauuac cagcaauucc acaaucauca acccuaccaa ugagacagac      300

gauaccgcgg gaaacaagcc caauuaccag cggaaaccuc ucguuucuuu caaggaggac      360

cccacaccua gcgauaaccc guuuuccaaa cuguauaagg aaaccauuga gacguucgac      420

aauaacgaag aggagagcuc uuacuccuau gaagagauca augaucaaac caacgacaau      480

auuacagcuc gccuugauag aaucgacgaa aagcugagcg agauucucgg caugcugcau      540

acccuugugg uggccucugc cgggcccaca uccgcucggg auggaauccg cgacgccaug      600

auuggccuga gagaagagau gaucgagaaa auccggaccg aagcucucau gacgaacgac      660

cgccuggagg ccauggcgag acugcggaau gaagagagcg aaaagauggc caaagauaca      720

ucugacgagg ucucccucaa cccuaccagc gagaagcuga acaaucuucu ggaagggaac      780

gauuccgaca augaucucuc ucuggaggac uuuugaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10780
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10780
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcaccaga auuucacgga      120

gaagacgcaa acaacagagc aacaaaauuc uuagaaucaa ucaaaggaaa auucacaagc      180

ccaaaagacc caaaaaaaaa agacucaaua auaagcguaa acucaauaga cauagaagua      240

acaaaagaaa gcccaauaac aagcaacagc acaauaauaa acccaacaaa cgaaacagau      300

gacacagcug gaaauaaacc aaacuaccaa agaaaacccc uagucagcuu caaagaagac      360

cccacaccau cagacaaccc auucagcaaa cuauauaaag aaacaauaga aacauuugac      420

aacaacgaag aagaaucauc auacucauac gaagaaauaa acgaccaaac aaacgacaac      480

auaaccgcaa gauuagacag aauagaugaa aaacuaucag aaauacuagg aaugcuacac      540

acauuaguag uagcaagcgc aggaccaaca ucagcaagag acggaauaag agacgcaaug      600

auaggacuca gagaagaaau gauagaaaaa auaagaacag aagcacuaau gacaaacgac      660

agauuagaag caauggcaag acuaagaaau gaagaaucgg aaaaaauggc aaaagacaca      720

ucagacgaag uaagccuaaa cccaacauca gaaaaauuaa auaaccuacu agaaggaaac      780

gacagcgaca acgacuuauc acuagaagac uucuaaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10781
<211>  1079
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10781
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcgcccga guuccacggc      120

gaggacgcga acaaccgcgc gacaaaguuc cuagaaucaa ucaagggcaa auucacgagc      180

ccgaaagacc ccaagaaaaa ggacucaauc auaagcguga acucgaucga caucgagguc      240

acgaaagaga gcccgaucac aagcaacagc accauaauaa acccgaccaa cgaaacagac      300

gacaccgcgg gcaacaaacc gaacuaccaa agaaaaccgc ucgugagcuu caaagaagac      360

ccgaccccaa gcgacaaccc guucucaaaa cuauacaagg aaacgaucga gaccuucgac      420

aacaacgagg aagagagcuc guacucguac gaggaaauaa acgaccaaac aaacgacaac      480

auaaccgcac gccuagacag gaucgacgaa aaacucucgg aaauacucgg gaugcuacac      540

acgcucgugg ucgcgagcgc aggcccgacc ucggccaggg acggcaucag ggacgcaaug      600

auaggccugc gagaggaaau gaucgagaaa auacgcaccg aagcacucau gaccaacgac      660

agacucgaag ccauggccag gcucaggaac gaagaauccg aaaagauggc gaaagacacc      720

ucggacgagg ucucgcucaa ccccacgagc gagaaacuga acaaccuacu ggaagggaac      780

gacagcgaca acgaccuuuc ccucgaggac uucugaggac uaguaauaag gaaacuguau      840

gaaugucugu gggcaggaag ugaagagauc cuucuguaaa gguuuuugga auuaugucug      900

cugaauaaua aacuuuuuug aaauaauaaa ucugguagaa aaaugagauc uaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau     1020

cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu      1079


<210>  10782
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10782
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaguuugcuc cugaauucca uggagaagau gcaaacaaca gggcuacuaa auuccuagaa      240

ucaauaaagg gcaaauucac aucacccaaa gaucccaaga aaaaagauag uaucauaucu      300

gucaacucaa uagauauaga aguaaccaaa gaaagcccua uaacaucaaa uucaacuauu      360

aucaacccaa caaaugagac agaugauacu gcagggaaca agcccaauua ucaaagaaaa      420

ccucuaguaa guuucaaaga agacccuaca ccaagugaua aucccuuuuc uaaacuauac      480

aaagaaacca uagaaacauu ugauaacaau gaagaagaau ccagcuauuc auacgaagaa      540

auaaaugauc agacaaacga uaauauaaca gcaagauuag auaggauuga ugaaaaauua      600

agugaaauac uaggaaugcu ucacacauua guaguggcaa gugcaggacc uacaucugcu      660

cgggauggua uaagagaugc caugauuggu uuaagagaag aaaugauaga aaaaaucaga      720

acugaagcau uaaugaccaa ugacagauua gaagcuaugg caagacucag gaaugaggaa      780

agugaaaaga uggcaaaaga cacaucagau gaagugucuc ucaauccaac aucagagaaa      840

uugaacaacc uauuggaagg gaaugauagu gacaaugauc uaucacuuga agauuucuga      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10783
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10783
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgcgaccaa guuccuggag      240

agcaucaagg ggaaguucac cuccccgaag gaccccaaga agaaggacag caucaucucc      300

gugaacagca ucgacaucga ggucacgaag gaguccccca ucaccagcaa cuccaccauc      360

aucaacccca ccaacgagac ggacgacacc gccggcaaca agccgaacua ccagcggaag      420

ccccucguga gcuucaagga ggaccccacc cccuccgaca acccguucag caagcuguac      480

aaggagacca ucgagacguu cgacaacaac gaggaggagu ccagcuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccugg accggaucga cgagaagcuc      600

agcgagaucc uggggaugcu gcacacccuc guggucgccu ccgccggccc cacgagcgcg      660

cgcgacggga uccgggacgc caugaucggc cugcgcgagg agaugaucga gaagauccgg      720

accgaggccc ugaugaccaa cgaccgccuc gaggccaugg cgcggcugcg caacgaggag      780

uccgagaaga uggccaagga caccagcgac gagguguccc ugaaccccac gagcgagaag      840

cucaacaacc ugcuggaggg caacgacagc gacaacgacc ucucccugga ggacuucuga      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10784
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10784
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgccaccaa guuccucgag      240

uccaucaagg gcaaguucac cucccccaag gaccccaaga agaaggacuc caucaucucc      300

gucaacucca ucgacaucga ggucaccaag gaguccccca ucaccuccaa cuccaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagcgcaag      420

ccccucgucu ccuucaagga ggaccccacc cccuccgaca accccuucuc caagcucuac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggagu ccuccuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccucg accgcaucga cgagaagcuc      600

uccgagaucc ucggcaugcu ccacacccuc gucgucgccu ccgccggccc caccuccgcc      660

cgcgacggca uccgcgacgc caugaucggc cuccgcgagg agaugaucga gaagauccgc      720

accgaggccc ucaugaccaa cgaccgccuc gaggccaugg cccgccuccg caacgaggag      780

uccgagaaga uggccaagga caccuccgac gaggucuccc ucaaccccac cuccgagaag      840

cucaacaacc uccucgaggg caacgacucc gacaacgacc ucucccucga ggacuucuga      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10785
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10785
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagcaaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuauauca      300

gugaacagua ucgauauuga ggucacuaaa gaaagcccaa ucacguccaa uucuaccauu      360

aucaacccca caaaugagac ugacgauacc gccggaaaca agccuaauua ccagaggaaa      420

ccacucguuu cguucaagga ggaccccaca ccuucagaua acccauuuag caaacuuuau      480

aaggaaacca uagagacuuu cgacaauaac gaagaggaga guuccuacuc uuaugaagag      540

aucaaugauc aaacaaacga caauauuacc gcgcggcugg aucgcaucga cgaaaaguug      600

agcgagauuu uagguaugcu gcauacgcua gugguagcuu ccgccggccc cacuucagca      660

cgagauggga uccgugacgc caugauagga cucagagaag agaugauuga gaaaaucagg      720

accgaagcuc ugaugacaaa cgaccggcuu gaggcaaugg cccgccugag aaaugaagag      780

agugaaaaga uggcuaaaga uacuagcgac gaggugucuu ugaacccuac cuccgagaag      840

cucaacaauc ugcuggaagg caacgauuca gacaaugauc ucagcuuaga ggacuuuuga      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10786
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10786
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaaca gagccaccaa guuccuggag      240

agcaucaagg gcaaguucac cagccccaag gaccccaaga agaaggacag caucaucagc      300

gugaacagca ucgacaucga ggugaccaag gagagcccca ucaccagcaa cagcaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagagaaag      420

ccccugguga gcuucaagga ggaccccacc cccagcgaca accccuucag caagcuguac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggaga gcagcuacag cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gccagacugg acagaaucga cgagaagcug      600

agcgagaucc ugggcaugcu gcacacccug gugguggcca gcgccggccc caccagcgcc      660

agagacggca ucagagacgc caugaucggc cugagagagg agaugaucga gaagaucaga      720

accgaggccc ugaugaccaa cgacagacug gaggccaugg ccagacugag aaacgaggag      780

agcgagaaga uggccaagga caccagcgac gaggugagcc ugaaccccac cagcgagaag      840

cugaacaacc ugcuggaggg caacgacagc gacaacgacc ugagccugga ggacuucuga      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10787
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10787
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagccaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuaucagc      300

gugaacucca uugauaucga ggucacgaaa gaaucuccca uuaccagcaa uuccacaauc      360

aucaacccua ccaaugagac agacgauacc gcgggaaaca agcccaauua ccagcggaaa      420

ccucucguuu cuuucaagga ggaccccaca ccuagcgaua acccguuuuc caaacuguau      480

aaggaaacca uugagacguu cgacaauaac gaagaggaga gcucuuacuc cuaugaagag      540

aucaaugauc aaaccaacga caauauuaca gcucgccuug auagaaucga cgaaaagcug      600

agcgagauuc ucggcaugcu gcauacccuu gugguggccu cugccgggcc cacauccgcu      660

cgggauggaa uccgcgacgc caugauuggc cugagagaag agaugaucga gaaaauccgg      720

accgaagcuc ucaugacgaa cgaccgccug gaggccaugg cgagacugcg gaaugaagag      780

agcgaaaaga uggccaaaga uacaucugac gaggucuccc ucaacccuac cagcgagaag      840

cugaacaauc uucuggaagg gaacgauucc gacaaugauc ucucucugga ggacuuuuga      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10788
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10788
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcac cagaauuuca cggagaagac gcaaacaaca gagcaacaaa auucuuagaa      240

ucaaucaaag gaaaauucac aagcccaaaa gacccaaaaa aaaaagacuc aauaauaagc      300

guaaacucaa uagacauaga aguaacaaaa gaaagcccaa uaacaagcaa cagcacaaua      360

auaaacccaa caaacgaaac agaugacaca gcuggaaaua aaccaaacua ccaaagaaaa      420

ccccuaguca gcuucaaaga agaccccaca ccaucagaca acccauucag caaacuauau      480

aaagaaacaa uagaaacauu ugacaacaac gaagaagaau caucauacuc auacgaagaa      540

auaaacgacc aaacaaacga caacauaacc gcaagauuag acagaauaga ugaaaaacua      600

ucagaaauac uaggaaugcu acacacauua guaguagcaa gcgcaggacc aacaucagca      660

agagacggaa uaagagacgc aaugauagga cucagagaag aaaugauaga aaaaauaaga      720

acagaagcac uaaugacaaa cgacagauua gaagcaaugg caagacuaag aaaugaagaa      780

ucggaaaaaa uggcaaaaga cacaucagac gaaguaagcc uaaacccaac aucagaaaaa      840

uuaaauaacc uacuagaagg aaacgacagc gacaacgacu uaucacuaga agacuucuaa      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10789
<211>  1395
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10789
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcgc ccgaguucca cggcgaggac gcgaacaacc gcgcgacaaa guuccuagaa      240

ucaaucaagg gcaaauucac gagcccgaaa gaccccaaga aaaaggacuc aaucauaagc      300

gugaacucga ucgacaucga ggucacgaaa gagagcccga ucacaagcaa cagcaccaua      360

auaaacccga ccaacgaaac agacgacacc gcgggcaaca aaccgaacua ccaaagaaaa      420

ccgcucguga gcuucaaaga agacccgacc ccaagcgaca acccguucuc aaaacuauac      480

aaggaaacga ucgagaccuu cgacaacaac gaggaagaga gcucguacuc guacgaggaa      540

auaaacgacc aaacaaacga caacauaacc gcacgccuag acaggaucga cgaaaaacuc      600

ucggaaauac ucgggaugcu acacacgcuc guggucgcga gcgcaggccc gaccucggcc      660

agggacggca ucagggacgc aaugauaggc cugcgagagg aaaugaucga gaaaauacgc      720

accgaagcac ucaugaccaa cgacagacuc gaagccaugg ccaggcucag gaacgaagaa      780

uccgaaaaga uggcgaaaga caccucggac gaggucucgc ucaaccccac gagcgagaaa      840

cugaacaacc uacuggaagg gaacgacagc gacaacgacc uuucccucga ggacuucuga      900

ggacuaguga agggaacacc caaauuuaau ucagccuuaa gcacaauuaa uuaagaguga      960

aacguaauug uacaagcagu uggucaccca ccauagggca ugaucaacac cgcaaccuuu     1020

ccuuuuuccc ccagugauuc ugaaaaaccc cucuucccuu cagcuugcuu agauguucca     1080

aauuuaguaa gcuuaaggcg gccuacagaa gaaaaagaaa aaaaaggcca caaaaguucc     1140

cucucacuuu caguaaauaa aauaaaagca gcaacagaaa uaaagaaaua aaugaaauuc     1200

aaaaugaaau aaauauugug uugugcagca uuaaaaaauc aauaaaaauu aaaaaugagc     1260

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1380

agagccacca gaauu                                                      1395


<210>  10790
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10790
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca      120

acagggcuac uaaauuccua gaaucaauaa agggcaaauu cacaucaccc aaagauccca      180

agaaaaaaga uaguaucaua ucugucaacu caauagauau agaaguaacc aaagaaagcc      240

cuauaacauc aaauucaacu auuaucaacc caacaaauga gacagaugau acugcaggga      300

acaagcccaa uuaucaaaga aaaccucuag uaaguuucaa agaagacccu acaccaagug      360

auaaucccuu uucuaaacua uacaaagaaa ccauagaaac auuugauaac aaugaagaag      420

aauccagcua uucauacgaa gaaauaaaug aucagacaaa cgauaauaua acagcaagau      480

uagauaggau ugaugaaaaa uuaagugaaa uacuaggaau gcuucacaca uuaguagugg      540

caagugcagg accuacaucu gcucgggaug guauaagaga ugccaugauu gguuuaagag      600

aagaaaugau agaaaaaauc agaacugaag cauuaaugac caaugacaga uuagaagcua      660

uggcaagacu caggaaugag gaaagugaaa agauggcaaa agacacauca gaugaagugu      720

cucucaaucc aacaucagag aaauugaaca accuauugga agggaaugau agugacaaug      780

aucuaucacu ugaagauuuc ugaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10791
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10791
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgcgac caaguuccug gagagcauca aggggaaguu caccuccccg aaggacccca      180

agaagaagga cagcaucauc uccgugaaca gcaucgacau cgaggucacg aaggaguccc      240

ccaucaccag caacuccacc aucaucaacc ccaccaacga gacggacgac accgccggca      300

acaagccgaa cuaccagcgg aagccccucg ugagcuucaa ggaggacccc acccccuccg      360

acaacccguu cagcaagcug uacaaggaga ccaucgagac guucgacaac aacgaggagg      420

aguccagcua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

uggaccggau cgacgagaag cucagcgaga uccuggggau gcugcacacc cucguggucg      540

ccuccgccgg ccccacgagc gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg      600

aggagaugau cgagaagauc cggaccgagg cccugaugac caacgaccgc cucgaggcca      660

uggcgcggcu gcgcaacgag gaguccgaga agauggccaa ggacaccagc gacgaggugu      720

cccugaaccc cacgagcgag aagcucaaca accugcugga gggcaacgac agcgacaacg      780

accucucccu ggaggacuuc ugaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10792
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10792
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgccac caaguuccuc gaguccauca agggcaaguu caccuccccc aaggacccca      180

agaagaagga cuccaucauc uccgucaacu ccaucgacau cgaggucacc aaggaguccc      240

ccaucaccuc caacuccacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagcgc aagccccucg ucuccuucaa ggaggacccc acccccuccg      360

acaaccccuu cuccaagcuc uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

aguccuccua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

ucgaccgcau cgacgagaag cucuccgaga uccucggcau gcuccacacc cucgucgucg      540

ccuccgccgg ccccaccucc gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg      600

aggagaugau cgagaagauc cgcaccgagg cccucaugac caacgaccgc cucgaggcca      660

uggcccgccu ccgcaacgag gaguccgaga agauggccaa ggacaccucc gacgaggucu      720

cccucaaccc caccuccgag aagcucaaca accuccucga gggcaacgac uccgacaacg      780

accucucccu cgaggacuuc ugaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10793
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10793
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagcaac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuaua ucagugaaca guaucgauau ugaggucacu aaagaaagcc      240

caaucacguc caauucuacc auuaucaacc ccacaaauga gacugacgau accgccggaa      300

acaagccuaa uuaccagagg aaaccacucg uuucguucaa ggaggacccc acaccuucag      360

auaacccauu uagcaaacuu uauaaggaaa ccauagagac uuucgacaau aacgaagagg      420

agaguuccua cucuuaugaa gagaucaaug aucaaacaaa cgacaauauu accgcgcggc      480

uggaucgcau cgacgaaaag uugagcgaga uuuuagguau gcugcauacg cuagugguag      540

cuuccgccgg ccccacuuca gcacgagaug ggauccguga cgccaugaua ggacucagag      600

aagagaugau ugagaaaauc aggaccgaag cucugaugac aaacgaccgg cuugaggcaa      660

uggcccgccu gagaaaugaa gagagugaaa agauggcuaa agauacuagc gacgaggugu      720

cuuugaaccc uaccuccgag aagcucaaca aucugcugga aggcaacgau ucagacaaug      780

aucucagcuu agaggacuuu ugaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10794
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10794
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

acagagccac caaguuccug gagagcauca agggcaaguu caccagcccc aaggacccca      180

agaagaagga cagcaucauc agcgugaaca gcaucgacau cgaggugacc aaggagagcc      240

ccaucaccag caacagcacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagaga aagccccugg ugagcuucaa ggaggacccc acccccagcg      360

acaaccccuu cagcaagcug uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

agagcagcua cagcuacgag gagaucaacg accagaccaa cgacaacauc accgccagac      480

uggacagaau cgacgagaag cugagcgaga uccugggcau gcugcacacc cugguggugg      540

ccagcgccgg ccccaccagc gccagagacg gcaucagaga cgccaugauc ggccugagag      600

aggagaugau cgagaagauc agaaccgagg cccugaugac caacgacaga cuggaggcca      660

uggccagacu gagaaacgag gagagcgaga agauggccaa ggacaccagc gacgagguga      720

gccugaaccc caccagcgag aagcugaaca accugcugga gggcaacgac agcgacaacg      780

accugagccu ggaggacuuc ugaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10795
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10795
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagccac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuauc agcgugaacu ccauugauau cgaggucacg aaagaaucuc      240

ccauuaccag caauuccaca aucaucaacc cuaccaauga gacagacgau accgcgggaa      300

acaagcccaa uuaccagcgg aaaccucucg uuucuuucaa ggaggacccc acaccuagcg      360

auaacccguu uuccaaacug uauaaggaaa ccauugagac guucgacaau aacgaagagg      420

agagcucuua cuccuaugaa gagaucaaug aucaaaccaa cgacaauauu acagcucgcc      480

uugauagaau cgacgaaaag cugagcgaga uucucggcau gcugcauacc cuuguggugg      540

ccucugccgg gcccacaucc gcucgggaug gaauccgcga cgccaugauu ggccugagag      600

aagagaugau cgagaaaauc cggaccgaag cucucaugac gaacgaccgc cuggaggcca      660

uggcgagacu gcggaaugaa gagagcgaaa agauggccaa agauacaucu gacgaggucu      720

cccucaaccc uaccagcgag aagcugaaca aucuucugga agggaacgau uccgacaaug      780

aucucucucu ggaggacuuu ugaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10796
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10796
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg caccagaauu ucacggagaa gacgcaaaca      120

acagagcaac aaaauucuua gaaucaauca aaggaaaauu cacaagccca aaagacccaa      180

aaaaaaaaga cucaauaaua agcguaaacu caauagacau agaaguaaca aaagaaagcc      240

caauaacaag caacagcaca auaauaaacc caacaaacga aacagaugac acagcuggaa      300

auaaaccaaa cuaccaaaga aaaccccuag ucagcuucaa agaagacccc acaccaucag      360

acaacccauu cagcaaacua uauaaagaaa caauagaaac auuugacaac aacgaagaag      420

aaucaucaua cucauacgaa gaaauaaacg accaaacaaa cgacaacaua accgcaagau      480

uagacagaau agaugaaaaa cuaucagaaa uacuaggaau gcuacacaca uuaguaguag      540

caagcgcagg accaacauca gcaagagacg gaauaagaga cgcaaugaua ggacucagag      600

aagaaaugau agaaaaaaua agaacagaag cacuaaugac aaacgacaga uuagaagcaa      660

uggcaagacu aagaaaugaa gaaucggaaa aaauggcaaa agacacauca gacgaaguaa      720

gccuaaaccc aacaucagaa aaauuaaaua accuacuaga aggaaacgac agcgacaacg      780

acuuaucacu agaagacuuc uaaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10797
<211>  1078
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10797
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca      120

accgcgcgac aaaguuccua gaaucaauca agggcaaauu cacgagcccg aaagacccca      180

agaaaaagga cucaaucaua agcgugaacu cgaucgacau cgaggucacg aaagagagcc      240

cgaucacaag caacagcacc auaauaaacc cgaccaacga aacagacgac accgcgggca      300

acaaaccgaa cuaccaaaga aaaccgcucg ugagcuucaa agaagacccg accccaagcg      360

acaacccguu cucaaaacua uacaaggaaa cgaucgagac cuucgacaac aacgaggaag      420

agagcucgua cucguacgag gaaauaaacg accaaacaaa cgacaacaua accgcacgcc      480

uagacaggau cgacgaaaaa cucucggaaa uacucgggau gcuacacacg cucguggucg      540

cgagcgcagg cccgaccucg gccagggacg gcaucaggga cgcaaugaua ggccugcgag      600

aggaaaugau cgagaaaaua cgcaccgaag cacucaugac caacgacaga cucgaagcca      660

uggccaggcu caggaacgaa gaauccgaaa agauggcgaa agacaccucg gacgaggucu      720

cgcucaaccc cacgagcgag aaacugaaca accuacugga agggaacgac agcgacaacg      780

accuuucccu cgaggacuuc ugaggacuag uggaagcauu uuccuggcug auuaaaagaa      840

auuacucagc uauggucauc uguuccuguu agaaggcuau gcagcauauu auauacuaug      900

cgcauguuau gaaaugcaua auaaaaaauu uuaaaaaauc uaaaagaucu aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1020

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1078


<210>  10798
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10798
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaguuugcuc cugaauucca uggagaagau gcaaacaaca gggcuacuaa auuccuagaa      240

ucaauaaagg gcaaauucac aucacccaaa gaucccaaga aaaaagauag uaucauaucu      300

gucaacucaa uagauauaga aguaaccaaa gaaagcccua uaacaucaaa uucaacuauu      360

aucaacccaa caaaugagac agaugauacu gcagggaaca agcccaauua ucaaagaaaa      420

ccucuaguaa guuucaaaga agacccuaca ccaagugaua aucccuuuuc uaaacuauac      480

aaagaaacca uagaaacauu ugauaacaau gaagaagaau ccagcuauuc auacgaagaa      540

auaaaugauc agacaaacga uaauauaaca gcaagauuag auaggauuga ugaaaaauua      600

agugaaauac uaggaaugcu ucacacauua guaguggcaa gugcaggacc uacaucugcu      660

cgggauggua uaagagaugc caugauuggu uuaagagaag aaaugauaga aaaaaucaga      720

acugaagcau uaaugaccaa ugacagauua gaagcuaugg caagacucag gaaugaggaa      780

agugaaaaga uggcaaaaga cacaucagau gaagugucuc ucaauccaac aucagagaaa      840

uugaacaacc uauuggaagg gaaugauagu gacaaugauc uaucacuuga agauuucuga      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10799
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10799
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgcgaccaa guuccuggag      240

agcaucaagg ggaaguucac cuccccgaag gaccccaaga agaaggacag caucaucucc      300

gugaacagca ucgacaucga ggucacgaag gaguccccca ucaccagcaa cuccaccauc      360

aucaacccca ccaacgagac ggacgacacc gccggcaaca agccgaacua ccagcggaag      420

ccccucguga gcuucaagga ggaccccacc cccuccgaca acccguucag caagcuguac      480

aaggagacca ucgagacguu cgacaacaac gaggaggagu ccagcuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccugg accggaucga cgagaagcuc      600

agcgagaucc uggggaugcu gcacacccuc guggucgccu ccgccggccc cacgagcgcg      660

cgcgacggga uccgggacgc caugaucggc cugcgcgagg agaugaucga gaagauccgg      720

accgaggccc ugaugaccaa cgaccgccuc gaggccaugg cgcggcugcg caacgaggag      780

uccgagaaga uggccaagga caccagcgac gagguguccc ugaaccccac gagcgagaag      840

cucaacaacc ugcuggaggg caacgacagc gacaacgacc ucucccugga ggacuucuga      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10800
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10800
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgccaccaa guuccucgag      240

uccaucaagg gcaaguucac cucccccaag gaccccaaga agaaggacuc caucaucucc      300

gucaacucca ucgacaucga ggucaccaag gaguccccca ucaccuccaa cuccaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagcgcaag      420

ccccucgucu ccuucaagga ggaccccacc cccuccgaca accccuucuc caagcucuac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggagu ccuccuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccucg accgcaucga cgagaagcuc      600

uccgagaucc ucggcaugcu ccacacccuc gucgucgccu ccgccggccc caccuccgcc      660

cgcgacggca uccgcgacgc caugaucggc cuccgcgagg agaugaucga gaagauccgc      720

accgaggccc ucaugaccaa cgaccgccuc gaggccaugg cccgccuccg caacgaggag      780

uccgagaaga uggccaagga caccuccgac gaggucuccc ucaaccccac cuccgagaag      840

cucaacaacc uccucgaggg caacgacucc gacaacgacc ucucccucga ggacuucuga      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10801
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10801
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagcaaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuauauca      300

gugaacagua ucgauauuga ggucacuaaa gaaagcccaa ucacguccaa uucuaccauu      360

aucaacccca caaaugagac ugacgauacc gccggaaaca agccuaauua ccagaggaaa      420

ccacucguuu cguucaagga ggaccccaca ccuucagaua acccauuuag caaacuuuau      480

aaggaaacca uagagacuuu cgacaauaac gaagaggaga guuccuacuc uuaugaagag      540

aucaaugauc aaacaaacga caauauuacc gcgcggcugg aucgcaucga cgaaaaguug      600

agcgagauuu uagguaugcu gcauacgcua gugguagcuu ccgccggccc cacuucagca      660

cgagauggga uccgugacgc caugauagga cucagagaag agaugauuga gaaaaucagg      720

accgaagcuc ugaugacaaa cgaccggcuu gaggcaaugg cccgccugag aaaugaagag      780

agugaaaaga uggcuaaaga uacuagcgac gaggugucuu ugaacccuac cuccgagaag      840

cucaacaauc ugcuggaagg caacgauuca gacaaugauc ucagcuuaga ggacuuuuga      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10802
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10802
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaaca gagccaccaa guuccuggag      240

agcaucaagg gcaaguucac cagccccaag gaccccaaga agaaggacag caucaucagc      300

gugaacagca ucgacaucga ggugaccaag gagagcccca ucaccagcaa cagcaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagagaaag      420

ccccugguga gcuucaagga ggaccccacc cccagcgaca accccuucag caagcuguac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggaga gcagcuacag cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gccagacugg acagaaucga cgagaagcug      600

agcgagaucc ugggcaugcu gcacacccug gugguggcca gcgccggccc caccagcgcc      660

agagacggca ucagagacgc caugaucggc cugagagagg agaugaucga gaagaucaga      720

accgaggccc ugaugaccaa cgacagacug gaggccaugg ccagacugag aaacgaggag      780

agcgagaaga uggccaagga caccagcgac gaggugagcc ugaaccccac cagcgagaag      840

cugaacaacc ugcuggaggg caacgacagc gacaacgacc ugagccugga ggacuucuga      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10803
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10803
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagccaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuaucagc      300

gugaacucca uugauaucga ggucacgaaa gaaucuccca uuaccagcaa uuccacaauc      360

aucaacccua ccaaugagac agacgauacc gcgggaaaca agcccaauua ccagcggaaa      420

ccucucguuu cuuucaagga ggaccccaca ccuagcgaua acccguuuuc caaacuguau      480

aaggaaacca uugagacguu cgacaauaac gaagaggaga gcucuuacuc cuaugaagag      540

aucaaugauc aaaccaacga caauauuaca gcucgccuug auagaaucga cgaaaagcug      600

agcgagauuc ucggcaugcu gcauacccuu gugguggccu cugccgggcc cacauccgcu      660

cgggauggaa uccgcgacgc caugauuggc cugagagaag agaugaucga gaaaauccgg      720

accgaagcuc ucaugacgaa cgaccgccug gaggccaugg cgagacugcg gaaugaagag      780

agcgaaaaga uggccaaaga uacaucugac gaggucuccc ucaacccuac cagcgagaag      840

cugaacaauc uucuggaagg gaacgauucc gacaaugauc ucucucugga ggacuuuuga      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10804
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10804
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcac cagaauuuca cggagaagac gcaaacaaca gagcaacaaa auucuuagaa      240

ucaaucaaag gaaaauucac aagcccaaaa gacccaaaaa aaaaagacuc aauaauaagc      300

guaaacucaa uagacauaga aguaacaaaa gaaagcccaa uaacaagcaa cagcacaaua      360

auaaacccaa caaacgaaac agaugacaca gcuggaaaua aaccaaacua ccaaagaaaa      420

ccccuaguca gcuucaaaga agaccccaca ccaucagaca acccauucag caaacuauau      480

aaagaaacaa uagaaacauu ugacaacaac gaagaagaau caucauacuc auacgaagaa      540

auaaacgacc aaacaaacga caacauaacc gcaagauuag acagaauaga ugaaaaacua      600

ucagaaauac uaggaaugcu acacacauua guaguagcaa gcgcaggacc aacaucagca      660

agagacggaa uaagagacgc aaugauagga cucagagaag aaaugauaga aaaaauaaga      720

acagaagcac uaaugacaaa cgacagauua gaagcaaugg caagacuaag aaaugaagaa      780

ucggaaaaaa uggcaaaaga cacaucagac gaaguaagcc uaaacccaac aucagaaaaa      840

uuaaauaacc uacuagaagg aaacgacagc gacaacgacu uaucacuaga agacuucuaa      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10805
<211>  1175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design d-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10805
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcgc ccgaguucca cggcgaggac gcgaacaacc gcgcgacaaa guuccuagaa      240

ucaaucaagg gcaaauucac gagcccgaaa gaccccaaga aaaaggacuc aaucauaagc      300

gugaacucga ucgacaucga ggucacgaaa gagagcccga ucacaagcaa cagcaccaua      360

auaaacccga ccaacgaaac agacgacacc gcgggcaaca aaccgaacua ccaaagaaaa      420

ccgcucguga gcuucaaaga agacccgacc ccaagcgaca acccguucuc aaaacuauac      480

aaggaaacga ucgagaccuu cgacaacaac gaggaagaga gcucguacuc guacgaggaa      540

auaaacgacc aaacaaacga caacauaacc gcacgccuag acaggaucga cgaaaaacuc      600

ucggaaauac ucgggaugcu acacacgcuc guggucgcga gcgcaggccc gaccucggcc      660

agggacggca ucagggacgc aaugauaggc cugcgagagg aaaugaucga gaaaauacgc      720

accgaagcac ucaugaccaa cgacagacuc gaagccaugg ccaggcucag gaacgaagaa      780

uccgaaaaga uggcgaaaga caccucggac gaggucucgc ucaaccccac gagcgagaaa      840

cugaacaacc uacuggaagg gaacgacagc gacaacgacc uuucccucga ggacuucuga      900

ggacuagugg aagcauuuuc cuggcugauu aaaagaaauu acucagcuau ggucaucugu      960

uccuguuaga aggcuaugca gcauauuaua uacuaugcgc auguuaugaa augcauaaua     1020

aaaaauuuua aaaaaucuaa aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1140

cccccccaaa ggcucuuuuc agagccacca gaauu                                1175


<210>  10806
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10806
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca acagggcuac uaaauuccua      180

gaaucaauaa agggcaaauu cacaucaccc aaagauccca agaaaaaaga uaguaucaua      240

ucugucaacu caauagauau agaaguaacc aaagaaagcc cuauaacauc aaauucaacu      300

auuaucaacc caacaaauga gacagaugau acugcaggga acaagcccaa uuaucaaaga      360

aaaccucuag uaaguuucaa agaagacccu acaccaagug auaaucccuu uucuaaacua      420

uacaaagaaa ccauagaaac auuugauaac aaugaagaag aauccagcua uucauacgaa      480

gaaauaaaug aucagacaaa cgauaauaua acagcaagau uagauaggau ugaugaaaaa      540

uuaagugaaa uacuaggaau gcuucacaca uuaguagugg caagugcagg accuacaucu      600

gcucgggaug guauaagaga ugccaugauu gguuuaagag aagaaaugau agaaaaaauc      660

agaacugaag cauuaaugac caaugacaga uuagaagcua uggcaagacu caggaaugag      720

gaaagugaaa agauggcaaa agacacauca gaugaagugu cucucaaucc aacaucagag      780

aaauugaaca accuauugga agggaaugau agugacaaug aucuaucacu ugaagauuuc      840

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10807
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10807
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgcgac caaguuccug      180

gagagcauca aggggaaguu caccuccccg aaggacccca agaagaagga cagcaucauc      240

uccgugaaca gcaucgacau cgaggucacg aaggaguccc ccaucaccag caacuccacc      300

aucaucaacc ccaccaacga gacggacgac accgccggca acaagccgaa cuaccagcgg      360

aagccccucg ugagcuucaa ggaggacccc acccccuccg acaacccguu cagcaagcug      420

uacaaggaga ccaucgagac guucgacaac aacgaggagg aguccagcua cuccuacgag      480

gagaucaacg accagaccaa cgacaacauc accgcccgcc uggaccggau cgacgagaag      540

cucagcgaga uccuggggau gcugcacacc cucguggucg ccuccgccgg ccccacgagc      600

gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg aggagaugau cgagaagauc      660

cggaccgagg cccugaugac caacgaccgc cucgaggcca uggcgcggcu gcgcaacgag      720

gaguccgaga agauggccaa ggacaccagc gacgaggugu cccugaaccc cacgagcgag      780

aagcucaaca accugcugga gggcaacgac agcgacaacg accucucccu ggaggacuuc      840

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10808
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10808
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgccac caaguuccuc      180

gaguccauca agggcaaguu caccuccccc aaggacccca agaagaagga cuccaucauc      240

uccgucaacu ccaucgacau cgaggucacc aaggaguccc ccaucaccuc caacuccacc      300

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagcgc      360

aagccccucg ucuccuucaa ggaggacccc acccccuccg acaaccccuu cuccaagcuc      420

uacaaggaga ccaucgagac cuucgacaac aacgaggagg aguccuccua cuccuacgag      480

gagaucaacg accagaccaa cgacaacauc accgcccgcc ucgaccgcau cgacgagaag      540

cucuccgaga uccucggcau gcuccacacc cucgucgucg ccuccgccgg ccccaccucc      600

gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg aggagaugau cgagaagauc      660

cgcaccgagg cccucaugac caacgaccgc cucgaggcca uggcccgccu ccgcaacgag      720

gaguccgaga agauggccaa ggacaccucc gacgaggucu cccucaaccc caccuccgag      780

aagcucaaca accuccucga gggcaacgac uccgacaacg accucucccu cgaggacuuc      840

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10809
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10809
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagcaac caaauuccug      180

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuaua      240

ucagugaaca guaucgauau ugaggucacu aaagaaagcc caaucacguc caauucuacc      300

auuaucaacc ccacaaauga gacugacgau accgccggaa acaagccuaa uuaccagagg      360

aaaccacucg uuucguucaa ggaggacccc acaccuucag auaacccauu uagcaaacuu      420

uauaaggaaa ccauagagac uuucgacaau aacgaagagg agaguuccua cucuuaugaa      480

gagaucaaug aucaaacaaa cgacaauauu accgcgcggc uggaucgcau cgacgaaaag      540

uugagcgaga uuuuagguau gcugcauacg cuagugguag cuuccgccgg ccccacuuca      600

gcacgagaug ggauccguga cgccaugaua ggacucagag aagagaugau ugagaaaauc      660

aggaccgaag cucugaugac aaacgaccgg cuugaggcaa uggcccgccu gagaaaugaa      720

gagagugaaa agauggcuaa agauacuagc gacgaggugu cuuugaaccc uaccuccgag      780

aagcucaaca aucugcugga aggcaacgau ucagacaaug aucucagcuu agaggacuuu      840

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10810
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10810
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaaguucg cccccgaguu ccacggcgag gacgccaaca acagagccac caaguuccug      180

gagagcauca agggcaaguu caccagcccc aaggacccca agaagaagga cagcaucauc      240

agcgugaaca gcaucgacau cgaggugacc aaggagagcc ccaucaccag caacagcacc      300

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagaga      360

aagccccugg ugagcuucaa ggaggacccc acccccagcg acaaccccuu cagcaagcug      420

uacaaggaga ccaucgagac cuucgacaac aacgaggagg agagcagcua cagcuacgag      480

gagaucaacg accagaccaa cgacaacauc accgccagac uggacagaau cgacgagaag      540

cugagcgaga uccugggcau gcugcacacc cugguggugg ccagcgccgg ccccaccagc      600

gccagagacg gcaucagaga cgccaugauc ggccugagag aggagaugau cgagaagauc      660

agaaccgagg cccugaugac caacgacaga cuggaggcca uggccagacu gagaaacgag      720

gagagcgaga agauggccaa ggacaccagc gacgagguga gccugaaccc caccagcgag      780

aagcugaaca accugcugga gggcaacgac agcgacaacg accugagccu ggaggacuuc      840

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10811
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10811
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagccac caaauuccug      180

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuauc      240

agcgugaacu ccauugauau cgaggucacg aaagaaucuc ccauuaccag caauuccaca      300

aucaucaacc cuaccaauga gacagacgau accgcgggaa acaagcccaa uuaccagcgg      360

aaaccucucg uuucuuucaa ggaggacccc acaccuagcg auaacccguu uuccaaacug      420

uauaaggaaa ccauugagac guucgacaau aacgaagagg agagcucuua cuccuaugaa      480

gagaucaaug aucaaaccaa cgacaauauu acagcucgcc uugauagaau cgacgaaaag      540

cugagcgaga uucucggcau gcugcauacc cuuguggugg ccucugccgg gcccacaucc      600

gcucgggaug gaauccgcga cgccaugauu ggccugagag aagagaugau cgagaaaauc      660

cggaccgaag cucucaugac gaacgaccgc cuggaggcca uggcgagacu gcggaaugaa      720

gagagcgaaa agauggccaa agauacaucu gacgaggucu cccucaaccc uaccagcgag      780

aagcugaaca aucuucugga agggaacgau uccgacaaug aucucucucu ggaggacuuu      840

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10812
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10812
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaaaaauucg caccagaauu ucacggagaa gacgcaaaca acagagcaac aaaauucuua      180

gaaucaauca aaggaaaauu cacaagccca aaagacccaa aaaaaaaaga cucaauaaua      240

agcguaaacu caauagacau agaaguaaca aaagaaagcc caauaacaag caacagcaca      300

auaauaaacc caacaaacga aacagaugac acagcuggaa auaaaccaaa cuaccaaaga      360

aaaccccuag ucagcuucaa agaagacccc acaccaucag acaacccauu cagcaaacua      420

uauaaagaaa caauagaaac auuugacaac aacgaagaag aaucaucaua cucauacgaa      480

gaaauaaacg accaaacaaa cgacaacaua accgcaagau uagacagaau agaugaaaaa      540

cuaucagaaa uacuaggaau gcuacacaca uuaguaguag caagcgcagg accaacauca      600

gcaagagacg gaauaagaga cgcaaugaua ggacucagag aagaaaugau agaaaaaaua      660

agaacagaag cacuaaugac aaacgacaga uuagaagcaa uggcaagacu aagaaaugaa      720

gaaucggaaa aaauggcaaa agacacauca gacgaaguaa gccuaaaccc aacaucagaa      780

aaauuaaaua accuacuaga aggaaacgac agcgacaacg acuuaucacu agaagacuuc      840

uaaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10813
<211>  1055
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10813
gggagaauau aagcguuggc ggagcgucgg uuguagcacu cugcgcgccc gcucuucugc       60

ugcuguuugu cuacuuccuc cugcuucccc gccgccgccg ccgccaucaa gcuuaccaug      120

gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca accgcgcgac aaaguuccua      180

gaaucaauca agggcaaauu cacgagcccg aaagacccca agaaaaagga cucaaucaua      240

agcgugaacu cgaucgacau cgaggucacg aaagagagcc cgaucacaag caacagcacc      300

auaauaaacc cgaccaacga aacagacgac accgcgggca acaaaccgaa cuaccaaaga      360

aaaccgcucg ugagcuucaa agaagacccg accccaagcg acaacccguu cucaaaacua      420

uacaaggaaa cgaucgagac cuucgacaac aacgaggaag agagcucgua cucguacgag      480

gaaauaaacg accaaacaaa cgacaacaua accgcacgcc uagacaggau cgacgaaaaa      540

cucucggaaa uacucgggau gcuacacacg cucguggucg cgagcgcagg cccgaccucg      600

gccagggacg gcaucaggga cgcaaugaua ggccugcgag aggaaaugau cgagaaaaua      660

cgcaccgaag cacucaugac caacgacaga cucgaagcca uggccaggcu caggaacgaa      720

gaauccgaaa agauggcgaa agacaccucg gacgaggucu cgcucaaccc cacgagcgag      780

aaacugaaca accuacugga agggaacgac agcgacaacg accuuucccu cgaggacuuc      840

ugaggacuag uguccaccug ucccuccugg gcugcuggau ugucucguuu uccugccaaa      900

uaaacaggau cagcgcuuua cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     1020

cccccccaaa ggcucuuuuc agagccacca gaauu                                1055


<210>  10814
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10814
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaguu ugcuccugaa      120

uuccauggag aagaugcaaa caacagggcu acuaaauucc uagaaucaau aaagggcaaa      180

uucacaucac ccaaagaucc caagaaaaaa gauaguauca uaucugucaa cucaauagau      240

auagaaguaa ccaaagaaag cccuauaaca ucaaauucaa cuauuaucaa cccaacaaau      300

gagacagaug auacugcagg gaacaagccc aauuaucaaa gaaaaccucu aguaaguuuc      360

aaagaagacc cuacaccaag ugauaauccc uuuucuaaac uauacaaaga aaccauagaa      420

acauuugaua acaaugaaga agaauccagc uauucauacg aagaaauaaa ugaucagaca      480

aacgauaaua uaacagcaag auuagauagg auugaugaaa aauuaaguga aauacuagga      540

augcuucaca cauuaguagu ggcaagugca ggaccuacau cugcucggga ugguauaaga      600

gaugccauga uugguuuaag agaagaaaug auagaaaaaa ucagaacuga agcauuaaug      660

accaaugaca gauuagaagc uauggcaaga cucaggaaug aggaaaguga aaagauggca      720

aaagacacau cagaugaagu gucucucaau ccaacaucag agaaauugaa caaccuauug      780

gaagggaaug auagugacaa ugaucuauca cuugaagauu ucugaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10815
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10815
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcg accaaguucc uggagagcau caaggggaag      180

uucaccuccc cgaaggaccc caagaagaag gacagcauca ucuccgugaa cagcaucgac      240

aucgagguca cgaaggaguc ccccaucacc agcaacucca ccaucaucaa ccccaccaac      300

gagacggacg acaccgccgg caacaagccg aacuaccagc ggaagccccu cgugagcuuc      360

aaggaggacc ccacccccuc cgacaacccg uucagcaagc uguacaagga gaccaucgag      420

acguucgaca acaacgagga ggaguccagc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccuggaccgg aucgacgaga agcucagcga gauccugggg      540

augcugcaca cccucguggu cgccuccgcc ggccccacga gcgcgcgcga cgggauccgg      600

gacgccauga ucggccugcg cgaggagaug aucgagaaga uccggaccga ggcccugaug      660

accaacgacc gccucgaggc cauggcgcgg cugcgcaacg aggaguccga gaagauggcc      720

aaggacacca gcgacgaggu gucccugaac cccacgagcg agaagcucaa caaccugcug      780

gagggcaacg acagcgacaa cgaccucucc cuggaggacu ucugaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10816
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10816
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcc accaaguucc ucgaguccau caagggcaag      180

uucaccuccc ccaaggaccc caagaagaag gacuccauca ucuccgucaa cuccaucgac      240

aucgagguca ccaaggaguc ccccaucacc uccaacucca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccagc gcaagccccu cgucuccuuc      360

aaggaggacc ccacccccuc cgacaacccc uucuccaagc ucuacaagga gaccaucgag      420

accuucgaca acaacgagga ggaguccucc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccucgaccgc aucgacgaga agcucuccga gauccucggc      540

augcuccaca cccucgucgu cgccuccgcc ggccccaccu ccgcccgcga cggcauccgc      600

gacgccauga ucggccuccg cgaggagaug aucgagaaga uccgcaccga ggcccucaug      660

accaacgacc gccucgaggc cauggcccgc cuccgcaacg aggaguccga gaagauggcc      720

aaggacaccu ccgacgaggu cucccucaac cccaccuccg agaagcucaa caaccuccuc      780

gagggcaacg acuccgacaa cgaccucucc cucgaggacu ucugaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10817
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10817
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagca accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua uaucagugaa caguaucgau      240

auugagguca cuaaagaaag cccaaucacg uccaauucua ccauuaucaa ccccacaaau      300

gagacugacg auaccgccgg aaacaagccu aauuaccaga ggaaaccacu cguuucguuc      360

aaggaggacc ccacaccuuc agauaaccca uuuagcaaac uuuauaagga aaccauagag      420

acuuucgaca auaacgaaga ggagaguucc uacucuuaug aagagaucaa ugaucaaaca      480

aacgacaaua uuaccgcgcg gcuggaucgc aucgacgaaa aguugagcga gauuuuaggu      540

augcugcaua cgcuaguggu agcuuccgcc ggccccacuu cagcacgaga ugggauccgu      600

gacgccauga uaggacucag agaagagaug auugagaaaa ucaggaccga agcucugaug      660

acaaacgacc ggcuugaggc aauggcccgc cugagaaaug aagagaguga aaagauggcu      720

aaagauacua gcgacgaggu gucuuugaac ccuaccuccg agaagcucaa caaucugcug      780

gaaggcaacg auucagacaa ugaucucagc uuagaggacu uuugaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10818
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10818
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caacagagcc accaaguucc uggagagcau caagggcaag      180

uucaccagcc ccaaggaccc caagaagaag gacagcauca ucagcgugaa cagcaucgac      240

aucgagguga ccaaggagag ccccaucacc agcaacagca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccaga gaaagccccu ggugagcuuc      360

aaggaggacc ccacccccag cgacaacccc uucagcaagc uguacaagga gaccaucgag      420

accuucgaca acaacgagga ggagagcagc uacagcuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgccag acuggacaga aucgacgaga agcugagcga gauccugggc      540

augcugcaca cccugguggu ggccagcgcc ggccccacca gcgccagaga cggcaucaga      600

gacgccauga ucggccugag agaggagaug aucgagaaga ucagaaccga ggcccugaug      660

accaacgaca gacuggaggc cauggccaga cugagaaacg aggagagcga gaagauggcc      720

aaggacacca gcgacgaggu gagccugaac cccaccagcg agaagcugaa caaccugcug      780

gagggcaacg acagcgacaa cgaccugagc cuggaggacu ucugaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10819
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10819
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagcc accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua ucagcgugaa cuccauugau      240

aucgagguca cgaaagaauc ucccauuacc agcaauucca caaucaucaa cccuaccaau      300

gagacagacg auaccgcggg aaacaagccc aauuaccagc ggaaaccucu cguuucuuuc      360

aaggaggacc ccacaccuag cgauaacccg uuuuccaaac uguauaagga aaccauugag      420

acguucgaca auaacgaaga ggagagcucu uacuccuaug aagagaucaa ugaucaaacc      480

aacgacaaua uuacagcucg ccuugauaga aucgacgaaa agcugagcga gauucucggc      540

augcugcaua cccuuguggu ggccucugcc gggcccacau ccgcucggga uggaauccgc      600

gacgccauga uuggccugag agaagagaug aucgagaaaa uccggaccga agcucucaug      660

acgaacgacc gccuggaggc cauggcgaga cugcggaaug aagagagcga aaagauggcc      720

aaagauacau cugacgaggu cucccucaac ccuaccagcg agaagcugaa caaucuucug      780

gaagggaacg auuccgacaa ugaucucucu cuggaggacu uuugaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10820
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10820
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcaccagaa      120

uuucacggag aagacgcaaa caacagagca acaaaauucu uagaaucaau caaaggaaaa      180

uucacaagcc caaaagaccc aaaaaaaaaa gacucaauaa uaagcguaaa cucaauagac      240

auagaaguaa caaaagaaag cccaauaaca agcaacagca caauaauaaa cccaacaaac      300

gaaacagaug acacagcugg aaauaaacca aacuaccaaa gaaaaccccu agucagcuuc      360

aaagaagacc ccacaccauc agacaaccca uucagcaaac uauauaaaga aacaauagaa      420

acauuugaca acaacgaaga agaaucauca uacucauacg aagaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcaag auuagacaga auagaugaaa aacuaucaga aauacuagga      540

augcuacaca cauuaguagu agcaagcgca ggaccaacau cagcaagaga cggaauaaga      600

gacgcaauga uaggacucag agaagaaaug auagaaaaaa uaagaacaga agcacuaaug      660

acaaacgaca gauuagaagc aauggcaaga cuaagaaaug aagaaucgga aaaaauggca      720

aaagacacau cagacgaagu aagccuaaac ccaacaucag aaaaauuaaa uaaccuacua      780

gaaggaaacg acagcgacaa cgacuuauca cuagaagacu ucuaaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10821
<211>  1037
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10821
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcgcccgag      120

uuccacggcg aggacgcgaa caaccgcgcg acaaaguucc uagaaucaau caagggcaaa      180

uucacgagcc cgaaagaccc caagaaaaag gacucaauca uaagcgugaa cucgaucgac      240

aucgagguca cgaaagagag cccgaucaca agcaacagca ccauaauaaa cccgaccaac      300

gaaacagacg acaccgcggg caacaaaccg aacuaccaaa gaaaaccgcu cgugagcuuc      360

aaagaagacc cgaccccaag cgacaacccg uucucaaaac uauacaagga aacgaucgag      420

accuucgaca acaacgagga agagagcucg uacucguacg aggaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcacg ccuagacagg aucgacgaaa aacucucgga aauacucggg      540

augcuacaca cgcucguggu cgcgagcgca ggcccgaccu cggccaggga cggcaucagg      600

gacgcaauga uaggccugcg agaggaaaug aucgagaaaa uacgcaccga agcacucaug      660

accaacgaca gacucgaagc cauggccagg cucaggaacg aagaauccga aaagauggcg      720

aaagacaccu cggacgaggu cucgcucaac cccacgagcg agaaacugaa caaccuacug      780

gaagggaacg acagcgacaa cgaccuuucc cucgaggacu ucugaggacu aguguccacc      840

ugucccuccu gggcugcugg auugucucgu uuuccugcca aauaaacagg aucagcgcuu      900

uacagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu     1020

ucagagccac cagaauu                                                    1037


<210>  10822
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10822
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaguu ugcuccugaa uuccauggag aagaugcaaa caacagggcu      120

acuaaauucc uagaaucaau aaagggcaaa uucacaucac ccaaagaucc caagaaaaaa      180

gauaguauca uaucugucaa cucaauagau auagaaguaa ccaaagaaag cccuauaaca      240

ucaaauucaa cuauuaucaa cccaacaaau gagacagaug auacugcagg gaacaagccc      300

aauuaucaaa gaaaaccucu aguaaguuuc aaagaagacc cuacaccaag ugauaauccc      360

uuuucuaaac uauacaaaga aaccauagaa acauuugaua acaaugaaga agaauccagc      420

uauucauacg aagaaauaaa ugaucagaca aacgauaaua uaacagcaag auuagauagg      480

auugaugaaa aauuaaguga aauacuagga augcuucaca cauuaguagu ggcaagugca      540

ggaccuacau cugcucggga ugguauaaga gaugccauga uugguuuaag agaagaaaug      600

auagaaaaaa ucagaacuga agcauuaaug accaaugaca gauuagaagc uauggcaaga      660

cucaggaaug aggaaaguga aaagauggca aaagacacau cagaugaagu gucucucaau      720

ccaacaucag agaaauugaa caaccuauug gaagggaaug auagugacaa ugaucuauca      780

cuugaagauu ucugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10823
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10823
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcg      120

accaaguucc uggagagcau caaggggaag uucaccuccc cgaaggaccc caagaagaag      180

gacagcauca ucuccgugaa cagcaucgac aucgagguca cgaaggaguc ccccaucacc      240

agcaacucca ccaucaucaa ccccaccaac gagacggacg acaccgccgg caacaagccg      300

aacuaccagc ggaagccccu cgugagcuuc aaggaggacc ccacccccuc cgacaacccg      360

uucagcaagc uguacaagga gaccaucgag acguucgaca acaacgagga ggaguccagc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccuggaccgg      480

aucgacgaga agcucagcga gauccugggg augcugcaca cccucguggu cgccuccgcc      540

ggccccacga gcgcgcgcga cgggauccgg gacgccauga ucggccugcg cgaggagaug      600

aucgagaaga uccggaccga ggcccugaug accaacgacc gccucgaggc cauggcgcgg      660

cugcgcaacg aggaguccga gaagauggcc aaggacacca gcgacgaggu gucccugaac      720

cccacgagcg agaagcucaa caaccugcug gagggcaacg acagcgacaa cgaccucucc      780

cuggaggacu ucugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10824
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10824
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcc      120

accaaguucc ucgaguccau caagggcaag uucaccuccc ccaaggaccc caagaagaag      180

gacuccauca ucuccgucaa cuccaucgac aucgagguca ccaaggaguc ccccaucacc      240

uccaacucca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccagc gcaagccccu cgucuccuuc aaggaggacc ccacccccuc cgacaacccc      360

uucuccaagc ucuacaagga gaccaucgag accuucgaca acaacgagga ggaguccucc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccucgaccgc      480

aucgacgaga agcucuccga gauccucggc augcuccaca cccucgucgu cgccuccgcc      540

ggccccaccu ccgcccgcga cggcauccgc gacgccauga ucggccuccg cgaggagaug      600

aucgagaaga uccgcaccga ggcccucaug accaacgacc gccucgaggc cauggcccgc      660

cuccgcaacg aggaguccga gaagauggcc aaggacaccu ccgacgaggu cucccucaac      720

cccaccuccg agaagcucaa caaccuccuc gagggcaacg acuccgacaa cgaccucucc      780

cucgaggacu ucugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10825
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10825
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagca      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua uaucagugaa caguaucgau auugagguca cuaaagaaag cccaaucacg      240

uccaauucua ccauuaucaa ccccacaaau gagacugacg auaccgccgg aaacaagccu      300

aauuaccaga ggaaaccacu cguuucguuc aaggaggacc ccacaccuuc agauaaccca      360

uuuagcaaac uuuauaagga aaccauagag acuuucgaca auaacgaaga ggagaguucc      420

uacucuuaug aagagaucaa ugaucaaaca aacgacaaua uuaccgcgcg gcuggaucgc      480

aucgacgaaa aguugagcga gauuuuaggu augcugcaua cgcuaguggu agcuuccgcc      540

ggccccacuu cagcacgaga ugggauccgu gacgccauga uaggacucag agaagagaug      600

auugagaaaa ucaggaccga agcucugaug acaaacgacc ggcuugaggc aauggcccgc      660

cugagaaaug aagagaguga aaagauggcu aaagauacua gcgacgaggu gucuuugaac      720

ccuaccuccg agaagcucaa caaucugcug gaaggcaacg auucagacaa ugaucucagc      780

uuagaggacu uuugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10826
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10826
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caacagagcc      120

accaaguucc uggagagcau caagggcaag uucaccagcc ccaaggaccc caagaagaag      180

gacagcauca ucagcgugaa cagcaucgac aucgagguga ccaaggagag ccccaucacc      240

agcaacagca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccaga gaaagccccu ggugagcuuc aaggaggacc ccacccccag cgacaacccc      360

uucagcaagc uguacaagga gaccaucgag accuucgaca acaacgagga ggagagcagc      420

uacagcuacg aggagaucaa cgaccagacc aacgacaaca ucaccgccag acuggacaga      480

aucgacgaga agcugagcga gauccugggc augcugcaca cccugguggu ggccagcgcc      540

ggccccacca gcgccagaga cggcaucaga gacgccauga ucggccugag agaggagaug      600

aucgagaaga ucagaaccga ggcccugaug accaacgaca gacuggaggc cauggccaga      660

cugagaaacg aggagagcga gaagauggcc aaggacacca gcgacgaggu gagccugaac      720

cccaccagcg agaagcugaa caaccugcug gagggcaacg acagcgacaa cgaccugagc      780

cuggaggacu ucugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10827
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10827
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagcc      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua ucagcgugaa cuccauugau aucgagguca cgaaagaauc ucccauuacc      240

agcaauucca caaucaucaa cccuaccaau gagacagacg auaccgcggg aaacaagccc      300

aauuaccagc ggaaaccucu cguuucuuuc aaggaggacc ccacaccuag cgauaacccg      360

uuuuccaaac uguauaagga aaccauugag acguucgaca auaacgaaga ggagagcucu      420

uacuccuaug aagagaucaa ugaucaaacc aacgacaaua uuacagcucg ccuugauaga      480

aucgacgaaa agcugagcga gauucucggc augcugcaua cccuuguggu ggccucugcc      540

gggcccacau ccgcucggga uggaauccgc gacgccauga uuggccugag agaagagaug      600

aucgagaaaa uccggaccga agcucucaug acgaacgacc gccuggaggc cauggcgaga      660

cugcggaaug aagagagcga aaagauggcc aaagauacau cugacgaggu cucccucaac      720

ccuaccagcg agaagcugaa caaucuucug gaagggaacg auuccgacaa ugaucucucu      780

cuggaggacu uuugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10828
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10828
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcaccagaa uuucacggag aagacgcaaa caacagagca      120

acaaaauucu uagaaucaau caaaggaaaa uucacaagcc caaaagaccc aaaaaaaaaa      180

gacucaauaa uaagcguaaa cucaauagac auagaaguaa caaaagaaag cccaauaaca      240

agcaacagca caauaauaaa cccaacaaac gaaacagaug acacagcugg aaauaaacca      300

aacuaccaaa gaaaaccccu agucagcuuc aaagaagacc ccacaccauc agacaaccca      360

uucagcaaac uauauaaaga aacaauagaa acauuugaca acaacgaaga agaaucauca      420

uacucauacg aagaaauaaa cgaccaaaca aacgacaaca uaaccgcaag auuagacaga      480

auagaugaaa aacuaucaga aauacuagga augcuacaca cauuaguagu agcaagcgca      540

ggaccaacau cagcaagaga cggaauaaga gacgcaauga uaggacucag agaagaaaug      600

auagaaaaaa uaagaacaga agcacuaaug acaaacgaca gauuagaagc aauggcaaga      660

cuaagaaaug aagaaucgga aaaaauggca aaagacacau cagacgaagu aagccuaaac      720

ccaacaucag aaaaauuaaa uaaccuacua gaaggaaacg acagcgacaa cgacuuauca      780

cuagaagacu ucuaaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10829
<211>  1007
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10829
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcgcccgag uuccacggcg aggacgcgaa caaccgcgcg      120

acaaaguucc uagaaucaau caagggcaaa uucacgagcc cgaaagaccc caagaaaaag      180

gacucaauca uaagcgugaa cucgaucgac aucgagguca cgaaagagag cccgaucaca      240

agcaacagca ccauaauaaa cccgaccaac gaaacagacg acaccgcggg caacaaaccg      300

aacuaccaaa gaaaaccgcu cgugagcuuc aaagaagacc cgaccccaag cgacaacccg      360

uucucaaaac uauacaagga aacgaucgag accuucgaca acaacgagga agagagcucg      420

uacucguacg aggaaauaaa cgaccaaaca aacgacaaca uaaccgcacg ccuagacagg      480

aucgacgaaa aacucucgga aauacucggg augcuacaca cgcucguggu cgcgagcgca      540

ggcccgaccu cggccaggga cggcaucagg gacgcaauga uaggccugcg agaggaaaug      600

aucgagaaaa uacgcaccga agcacucaug accaacgaca gacucgaagc cauggccagg      660

cucaggaacg aagaauccga aaagauggcg aaagacaccu cggacgaggu cucgcucaac      720

cccacgagcg agaaacugaa caaccuacug gaagggaacg acagcgacaa cgaccuuucc      780

cucgaggacu ucugaggacu aguguccacc ugucccuccu gggcugcugg auugucucgu      840

uuuccugcca aauaaacagg aucagcgcuu uacagaucua aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc      960

cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu                   1007


<210>  10830
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10830
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aguuugcucc ugaauuccau ggagaagaug caaacaacag ggcuacuaaa      180

uuccuagaau caauaaaggg caaauucaca ucacccaaag aucccaagaa aaaagauagu      240

aucauaucug ucaacucaau agauauagaa guaaccaaag aaagcccuau aacaucaaau      300

ucaacuauua ucaacccaac aaaugagaca gaugauacug cagggaacaa gcccaauuau      360

caaagaaaac cucuaguaag uuucaaagaa gacccuacac caagugauaa ucccuuuucu      420

aaacuauaca aagaaaccau agaaacauuu gauaacaaug aagaagaauc cagcuauuca      480

uacgaagaaa uaaaugauca gacaaacgau aauauaacag caagauuaga uaggauugau      540

gaaaaauuaa gugaaauacu aggaaugcuu cacacauuag uaguggcaag ugcaggaccu      600

acaucugcuc gggaugguau aagagaugcc augauugguu uaagagaaga aaugauagaa      660

aaaaucagaa cugaagcauu aaugaccaau gacagauuag aagcuauggc aagacucagg      720

aaugaggaaa gugaaaagau ggcaaaagac acaucagaug aagugucucu caauccaaca      780

ucagagaaau ugaacaaccu auuggaaggg aaugauagug acaaugaucu aucacuugaa      840

gauuucugag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10831
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10831
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgcgaccaag      180

uuccuggaga gcaucaaggg gaaguucacc uccccgaagg accccaagaa gaaggacagc      240

aucaucuccg ugaacagcau cgacaucgag gucacgaagg agucccccau caccagcaac      300

uccaccauca ucaaccccac caacgagacg gacgacaccg ccggcaacaa gccgaacuac      360

cagcggaagc cccucgugag cuucaaggag gaccccaccc ccuccgacaa cccguucagc      420

aagcuguaca aggagaccau cgagacguuc gacaacaacg aggaggaguc cagcuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccugga ccggaucgac      540

gagaagcuca gcgagauccu ggggaugcug cacacccucg uggucgccuc cgccggcccc      600

acgagcgcgc gcgacgggau ccgggacgcc augaucggcc ugcgcgagga gaugaucgag      660

aagauccgga ccgaggcccu gaugaccaac gaccgccucg aggccauggc gcggcugcgc      720

aacgaggagu ccgagaagau ggccaaggac accagcgacg aggugucccu gaaccccacg      780

agcgagaagc ucaacaaccu gcuggagggc aacgacagcg acaacgaccu cucccuggag      840

gacuucugag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10832
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10832
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgccaccaag      180

uuccucgagu ccaucaaggg caaguucacc ucccccaagg accccaagaa gaaggacucc      240

aucaucuccg ucaacuccau cgacaucgag gucaccaagg agucccccau caccuccaac      300

uccaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagcgcaagc cccucgucuc cuucaaggag gaccccaccc ccuccgacaa ccccuucucc      420

aagcucuaca aggagaccau cgagaccuuc gacaacaacg aggaggaguc cuccuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccucga ccgcaucgac      540

gagaagcucu ccgagauccu cggcaugcuc cacacccucg ucgucgccuc cgccggcccc      600

accuccgccc gcgacggcau ccgcgacgcc augaucggcc uccgcgagga gaugaucgag      660

aagauccgca ccgaggcccu caugaccaac gaccgccucg aggccauggc ccgccuccgc      720

aacgaggagu ccgagaagau ggccaaggac accuccgacg aggucucccu caaccccacc      780

uccgagaagc ucaacaaccu ccucgagggc aacgacuccg acaacgaccu cucccucgag      840

gacuucugag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10833
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10833
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agcaaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuauaucag ugaacaguau cgauauugag gucacuaaag aaagcccaau cacguccaau      300

ucuaccauua ucaaccccac aaaugagacu gacgauaccg ccggaaacaa gccuaauuac      360

cagaggaaac cacucguuuc guucaaggag gaccccacac cuucagauaa cccauuuagc      420

aaacuuuaua aggaaaccau agagacuuuc gacaauaacg aagaggagag uuccuacucu      480

uaugaagaga ucaaugauca aacaaacgac aauauuaccg cgcggcugga ucgcaucgac      540

gaaaaguuga gcgagauuuu agguaugcug cauacgcuag ugguagcuuc cgccggcccc      600

acuucagcac gagaugggau ccgugacgcc augauaggac ucagagaaga gaugauugag      660

aaaaucagga ccgaagcucu gaugacaaac gaccggcuug aggcaauggc ccgccugaga      720

aaugaagaga gugaaaagau ggcuaaagau acuagcgacg aggugucuuu gaacccuacc      780

uccgagaagc ucaacaaucu gcuggaaggc aacgauucag acaaugaucu cagcuuagag      840

gacuuuugag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10834
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10834
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaacag agccaccaag      180

uuccuggaga gcaucaaggg caaguucacc agccccaagg accccaagaa gaaggacagc      240

aucaucagcg ugaacagcau cgacaucgag gugaccaagg agagccccau caccagcaac      300

agcaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagagaaagc cccuggugag cuucaaggag gaccccaccc ccagcgacaa ccccuucagc      420

aagcuguaca aggagaccau cgagaccuuc gacaacaacg aggaggagag cagcuacagc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg ccagacugga cagaaucgac      540

gagaagcuga gcgagauccu gggcaugcug cacacccugg ugguggccag cgccggcccc      600

accagcgcca gagacggcau cagagacgcc augaucggcc ugagagagga gaugaucgag      660

aagaucagaa ccgaggcccu gaugaccaac gacagacugg aggccauggc cagacugaga      720

aacgaggaga gcgagaagau ggccaaggac accagcgacg aggugagccu gaaccccacc      780

agcgagaagc ugaacaaccu gcuggagggc aacgacagcg acaacgaccu gagccuggag      840

gacuucugag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10835
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10835
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agccaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuaucagcg ugaacuccau ugauaucgag gucacgaaag aaucucccau uaccagcaau      300

uccacaauca ucaacccuac caaugagaca gacgauaccg cgggaaacaa gcccaauuac      360

cagcggaaac cucucguuuc uuucaaggag gaccccacac cuagcgauaa cccguuuucc      420

aaacuguaua aggaaaccau ugagacguuc gacaauaacg aagaggagag cucuuacucc      480

uaugaagaga ucaaugauca aaccaacgac aauauuacag cucgccuuga uagaaucgac      540

gaaaagcuga gcgagauucu cggcaugcug cauacccuug ugguggccuc ugccgggccc      600

acauccgcuc gggauggaau ccgcgacgcc augauuggcc ugagagaaga gaugaucgag      660

aaaauccgga ccgaagcucu caugacgaac gaccgccugg aggccauggc gagacugcgg      720

aaugaagaga gcgaaaagau ggccaaagau acaucugacg aggucucccu caacccuacc      780

agcgagaagc ugaacaaucu ucuggaaggg aacgauuccg acaaugaucu cucucuggag      840

gacuuuugag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10836
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10836
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcacc agaauuucac ggagaagacg caaacaacag agcaacaaaa      180

uucuuagaau caaucaaagg aaaauucaca agcccaaaag acccaaaaaa aaaagacuca      240

auaauaagcg uaaacucaau agacauagaa guaacaaaag aaagcccaau aacaagcaac      300

agcacaauaa uaaacccaac aaacgaaaca gaugacacag cuggaaauaa accaaacuac      360

caaagaaaac cccuagucag cuucaaagaa gaccccacac caucagacaa cccauucagc      420

aaacuauaua aagaaacaau agaaacauuu gacaacaacg aagaagaauc aucauacuca      480

uacgaagaaa uaaacgacca aacaaacgac aacauaaccg caagauuaga cagaauagau      540

gaaaaacuau cagaaauacu aggaaugcua cacacauuag uaguagcaag cgcaggacca      600

acaucagcaa gagacggaau aagagacgca augauaggac ucagagaaga aaugauagaa      660

aaaauaagaa cagaagcacu aaugacaaac gacagauuag aagcaauggc aagacuaaga      720

aaugaagaau cggaaaaaau ggcaaaagac acaucagacg aaguaagccu aaacccaaca      780

ucagaaaaau uaaauaaccu acuagaagga aacgacagcg acaacgacuu aucacuagaa      840

gacuucuaag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10837
<211>  1061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10837
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcgcc cgaguuccac ggcgaggacg cgaacaaccg cgcgacaaag      180

uuccuagaau caaucaaggg caaauucacg agcccgaaag accccaagaa aaaggacuca      240

aucauaagcg ugaacucgau cgacaucgag gucacgaaag agagcccgau cacaagcaac      300

agcaccauaa uaaacccgac caacgaaaca gacgacaccg cgggcaacaa accgaacuac      360

caaagaaaac cgcucgugag cuucaaagaa gacccgaccc caagcgacaa cccguucuca      420

aaacuauaca aggaaacgau cgagaccuuc gacaacaacg aggaagagag cucguacucg      480

uacgaggaaa uaaacgacca aacaaacgac aacauaaccg cacgccuaga caggaucgac      540

gaaaaacucu cggaaauacu cgggaugcua cacacgcucg uggucgcgag cgcaggcccg      600

accucggcca gggacggcau cagggacgca augauaggcc ugcgagagga aaugaucgag      660

aaaauacgca ccgaagcacu caugaccaac gacagacucg aagccauggc caggcucagg      720

aacgaagaau ccgaaaagau ggcgaaagac accucggacg aggucucgcu caaccccacg      780

agcgagaaac ugaacaaccu acuggaaggg aacgacagcg acaacgaccu uucccucgag      840

gacuucugag gacuaguguc caccuguccc uccugggcug cuggauuguc ucguuuuccu      900

gccaaauaaa caggaucagc gcuuuacaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc     1020

cccccccccc cccaaaggcu cuuuucagag ccaccagaau u                         1061


<210>  10838
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10838
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaagu uugcuccuga auuccaugga      120

gaagaugcaa acaacagggc uacuaaauuc cuagaaucaa uaaagggcaa auucacauca      180

cccaaagauc ccaagaaaaa agauaguauc auaucuguca acucaauaga uauagaagua      240

accaaagaaa gcccuauaac aucaaauuca acuauuauca acccaacaaa ugagacagau      300

gauacugcag ggaacaagcc caauuaucaa agaaaaccuc uaguaaguuu caaagaagac      360

ccuacaccaa gugauaaucc cuuuucuaaa cuauacaaag aaaccauaga aacauuugau      420

aacaaugaag aagaauccag cuauucauac gaagaaauaa augaucagac aaacgauaau      480

auaacagcaa gauuagauag gauugaugaa aaauuaagug aaauacuagg aaugcuucac      540

acauuaguag uggcaagugc aggaccuaca ucugcucggg augguauaag agaugccaug      600

auugguuuaa gagaagaaau gauagaaaaa aucagaacug aagcauuaau gaccaaugac      660

agauuagaag cuauggcaag acucaggaau gaggaaagug aaaagauggc aaaagacaca      720

ucagaugaag ugucucucaa uccaacauca gagaaauuga acaaccuauu ggaagggaau      780

gauagugaca augaucuauc acuugaagau uucugaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10839
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10839
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc gaccaaguuc cuggagagca ucaaggggaa guucaccucc      180

ccgaaggacc ccaagaagaa ggacagcauc aucuccguga acagcaucga caucgagguc      240

acgaaggagu cccccaucac cagcaacucc accaucauca accccaccaa cgagacggac      300

gacaccgccg gcaacaagcc gaacuaccag cggaagcccc ucgugagcuu caaggaggac      360

cccacccccu ccgacaaccc guucagcaag cuguacaagg agaccaucga gacguucgac      420

aacaacgagg aggaguccag cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccuggaccg gaucgacgag aagcucagcg agauccuggg gaugcugcac      540

acccucgugg ucgccuccgc cggccccacg agcgcgcgcg acgggauccg ggacgccaug      600

aucggccugc gcgaggagau gaucgagaag auccggaccg aggcccugau gaccaacgac      660

cgccucgagg ccauggcgcg gcugcgcaac gaggaguccg agaagauggc caaggacacc      720

agcgacgagg ugucccugaa ccccacgagc gagaagcuca acaaccugcu ggagggcaac      780

gacagcgaca acgaccucuc ccuggaggac uucugaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10840
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10840
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc caccaaguuc cucgagucca ucaagggcaa guucaccucc      180

cccaaggacc ccaagaagaa ggacuccauc aucuccguca acuccaucga caucgagguc      240

accaaggagu cccccaucac cuccaacucc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag cgcaagcccc ucgucuccuu caaggaggac      360

cccacccccu ccgacaaccc cuucuccaag cucuacaagg agaccaucga gaccuucgac      420

aacaacgagg aggaguccuc cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccucgaccg caucgacgag aagcucuccg agauccucgg caugcuccac      540

acccucgucg ucgccuccgc cggccccacc uccgcccgcg acggcauccg cgacgccaug      600

aucggccucc gcgaggagau gaucgagaag auccgcaccg aggcccucau gaccaacgac      660

cgccucgagg ccauggcccg ccuccgcaac gaggaguccg agaagauggc caaggacacc      720

uccgacgagg ucucccucaa ccccaccucc gagaagcuca acaaccuccu cgagggcaac      780

gacuccgaca acgaccucuc ccucgaggac uucugaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10841
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10841
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc aaccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu auaucaguga acaguaucga uauugagguc      240

acuaaagaaa gcccaaucac guccaauucu accauuauca accccacaaa ugagacugac      300

gauaccgccg gaaacaagcc uaauuaccag aggaaaccac ucguuucguu caaggaggac      360

cccacaccuu cagauaaccc auuuagcaaa cuuuauaagg aaaccauaga gacuuucgac      420

aauaacgaag aggagaguuc cuacucuuau gaagagauca augaucaaac aaacgacaau      480

auuaccgcgc ggcuggaucg caucgacgaa aaguugagcg agauuuuagg uaugcugcau      540

acgcuagugg uagcuuccgc cggccccacu ucagcacgag augggauccg ugacgccaug      600

auaggacuca gagaagagau gauugagaaa aucaggaccg aagcucugau gacaaacgac      660

cggcuugagg caauggcccg ccugagaaau gaagagagug aaaagauggc uaaagauacu      720

agcgacgagg ugucuuugaa cccuaccucc gagaagcuca acaaucugcu ggaaggcaac      780

gauucagaca augaucucag cuuagaggac uuuugaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10842
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10842
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaacagagc caccaaguuc cuggagagca ucaagggcaa guucaccagc      180

cccaaggacc ccaagaagaa ggacagcauc aucagcguga acagcaucga caucgaggug      240

accaaggaga gccccaucac cagcaacagc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag agaaagcccc uggugagcuu caaggaggac      360

cccaccccca gcgacaaccc cuucagcaag cuguacaagg agaccaucga gaccuucgac      420

aacaacgagg aggagagcag cuacagcuac gaggagauca acgaccagac caacgacaac      480

aucaccgcca gacuggacag aaucgacgag aagcugagcg agauccuggg caugcugcac      540

acccuggugg uggccagcgc cggccccacc agcgccagag acggcaucag agacgccaug      600

aucggccuga gagaggagau gaucgagaag aucagaaccg aggcccugau gaccaacgac      660

agacuggagg ccauggccag acugagaaac gaggagagcg agaagauggc caaggacacc      720

agcgacgagg ugagccugaa ccccaccagc gagaagcuga acaaccugcu ggagggcaac      780

gacagcgaca acgaccugag ccuggaggac uucugaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10843
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10843
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc caccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu aucagcguga acuccauuga uaucgagguc      240

acgaaagaau cucccauuac cagcaauucc acaaucauca acccuaccaa ugagacagac      300

gauaccgcgg gaaacaagcc caauuaccag cggaaaccuc ucguuucuuu caaggaggac      360

cccacaccua gcgauaaccc guuuuccaaa cuguauaagg aaaccauuga gacguucgac      420

aauaacgaag aggagagcuc uuacuccuau gaagagauca augaucaaac caacgacaau      480

auuacagcuc gccuugauag aaucgacgaa aagcugagcg agauucucgg caugcugcau      540

acccuugugg uggccucugc cgggcccaca uccgcucggg auggaauccg cgacgccaug      600

auuggccuga gagaagagau gaucgagaaa auccggaccg aagcucucau gacgaacgac      660

cgccuggagg ccauggcgag acugcggaau gaagagagcg aaaagauggc caaagauaca      720

ucugacgagg ucucccucaa cccuaccagc gagaagcuga acaaucuucu ggaagggaac      780

gauuccgaca augaucucuc ucuggaggac uuuugaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10844
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10844
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcaccaga auuucacgga      120

gaagacgcaa acaacagagc aacaaaauuc uuagaaucaa ucaaaggaaa auucacaagc      180

ccaaaagacc caaaaaaaaa agacucaaua auaagcguaa acucaauaga cauagaagua      240

acaaaagaaa gcccaauaac aagcaacagc acaauaauaa acccaacaaa cgaaacagau      300

gacacagcug gaaauaaacc aaacuaccaa agaaaacccc uagucagcuu caaagaagac      360

cccacaccau cagacaaccc auucagcaaa cuauauaaag aaacaauaga aacauuugac      420

aacaacgaag aagaaucauc auacucauac gaagaaauaa acgaccaaac aaacgacaac      480

auaaccgcaa gauuagacag aauagaugaa aaacuaucag aaauacuagg aaugcuacac      540

acauuaguag uagcaagcgc aggaccaaca ucagcaagag acggaauaag agacgcaaug      600

auaggacuca gagaagaaau gauagaaaaa auaagaacag aagcacuaau gacaaacgac      660

agauuagaag caauggcaag acuaagaaau gaagaaucgg aaaaaauggc aaaagacaca      720

ucagacgaag uaagccuaaa cccaacauca gaaaaauuaa auaaccuacu agaaggaaac      780

gacagcgaca acgacuuauc acuagaagac uucuaaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10845
<211>  1028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10845
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcgcccga guuccacggc      120

gaggacgcga acaaccgcgc gacaaaguuc cuagaaucaa ucaagggcaa auucacgagc      180

ccgaaagacc ccaagaaaaa ggacucaauc auaagcguga acucgaucga caucgagguc      240

acgaaagaga gcccgaucac aagcaacagc accauaauaa acccgaccaa cgaaacagac      300

gacaccgcgg gcaacaaacc gaacuaccaa agaaaaccgc ucgugagcuu caaagaagac      360

ccgaccccaa gcgacaaccc guucucaaaa cuauacaagg aaacgaucga gaccuucgac      420

aacaacgagg aagagagcuc guacucguac gaggaaauaa acgaccaaac aaacgacaac      480

auaaccgcac gccuagacag gaucgacgaa aaacucucgg aaauacucgg gaugcuacac      540

acgcucgugg ucgcgagcgc aggcccgacc ucggccaggg acggcaucag ggacgcaaug      600

auaggccugc gagaggaaau gaucgagaaa auacgcaccg aagcacucau gaccaacgac      660

agacucgaag ccauggccag gcucaggaac gaagaauccg aaaagauggc gaaagacacc      720

ucggacgagg ucucgcucaa ccccacgagc gagaaacuga acaaccuacu ggaagggaac      780

gacagcgaca acgaccuuuc ccucgaggac uucugaggac uaguguccac cugucccucc      840

ugggcugcug gauugucucg uuuuccugcc aaauaaacag gaucagcgcu uuacagaucu      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1020

ccagaauu                                                              1028


<210>  10846
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10846
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaagu uugcuccuga auuccaugga      120

gaagaugcaa acaacagggc uacuaaauuc cuagaaucaa uaaagggcaa auucacauca      180

cccaaagauc ccaagaaaaa agauaguauc auaucuguca acucaauaga uauagaagua      240

accaaagaaa gcccuauaac aucaaauuca acuauuauca acccaacaaa ugagacagau      300

gauacugcag ggaacaagcc caauuaucaa agaaaaccuc uaguaaguuu caaagaagac      360

ccuacaccaa gugauaaucc cuuuucuaaa cuauacaaag aaaccauaga aacauuugau      420

aacaaugaag aagaauccag cuauucauac gaagaaauaa augaucagac aaacgauaau      480

auaacagcaa gauuagauag gauugaugaa aaauuaagug aaauacuagg aaugcuucac      540

acauuaguag uggcaagugc aggaccuaca ucugcucggg augguauaag agaugccaug      600

auugguuuaa gagaagaaau gauagaaaaa aucagaacug aagcauuaau gaccaaugac      660

agauuagaag cuauggcaag acucaggaau gaggaaagug aaaagauggc aaaagacaca      720

ucagaugaag ugucucucaa uccaacauca gagaaauuga acaaccuauu ggaagggaau      780

gauagugaca augaucuauc acuugaagau uucugaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10847
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10847
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc gaccaaguuc cuggagagca ucaaggggaa guucaccucc      180

ccgaaggacc ccaagaagaa ggacagcauc aucuccguga acagcaucga caucgagguc      240

acgaaggagu cccccaucac cagcaacucc accaucauca accccaccaa cgagacggac      300

gacaccgccg gcaacaagcc gaacuaccag cggaagcccc ucgugagcuu caaggaggac      360

cccacccccu ccgacaaccc guucagcaag cuguacaagg agaccaucga gacguucgac      420

aacaacgagg aggaguccag cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccuggaccg gaucgacgag aagcucagcg agauccuggg gaugcugcac      540

acccucgugg ucgccuccgc cggccccacg agcgcgcgcg acgggauccg ggacgccaug      600

aucggccugc gcgaggagau gaucgagaag auccggaccg aggcccugau gaccaacgac      660

cgccucgagg ccauggcgcg gcugcgcaac gaggaguccg agaagauggc caaggacacc      720

agcgacgagg ugucccugaa ccccacgagc gagaagcuca acaaccugcu ggagggcaac      780

gacagcgaca acgaccucuc ccuggaggac uucugaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10848
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10848
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc caccaaguuc cucgagucca ucaagggcaa guucaccucc      180

cccaaggacc ccaagaagaa ggacuccauc aucuccguca acuccaucga caucgagguc      240

accaaggagu cccccaucac cuccaacucc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag cgcaagcccc ucgucuccuu caaggaggac      360

cccacccccu ccgacaaccc cuucuccaag cucuacaagg agaccaucga gaccuucgac      420

aacaacgagg aggaguccuc cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccucgaccg caucgacgag aagcucuccg agauccucgg caugcuccac      540

acccucgucg ucgccuccgc cggccccacc uccgcccgcg acggcauccg cgacgccaug      600

aucggccucc gcgaggagau gaucgagaag auccgcaccg aggcccucau gaccaacgac      660

cgccucgagg ccauggcccg ccuccgcaac gaggaguccg agaagauggc caaggacacc      720

uccgacgagg ucucccucaa ccccaccucc gagaagcuca acaaccuccu cgagggcaac      780

gacuccgaca acgaccucuc ccucgaggac uucugaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10849
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10849
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc aaccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu auaucaguga acaguaucga uauugagguc      240

acuaaagaaa gcccaaucac guccaauucu accauuauca accccacaaa ugagacugac      300

gauaccgccg gaaacaagcc uaauuaccag aggaaaccac ucguuucguu caaggaggac      360

cccacaccuu cagauaaccc auuuagcaaa cuuuauaagg aaaccauaga gacuuucgac      420

aauaacgaag aggagaguuc cuacucuuau gaagagauca augaucaaac aaacgacaau      480

auuaccgcgc ggcuggaucg caucgacgaa aaguugagcg agauuuuagg uaugcugcau      540

acgcuagugg uagcuuccgc cggccccacu ucagcacgag augggauccg ugacgccaug      600

auaggacuca gagaagagau gauugagaaa aucaggaccg aagcucugau gacaaacgac      660

cggcuugagg caauggcccg ccugagaaau gaagagagug aaaagauggc uaaagauacu      720

agcgacgagg ugucuuugaa cccuaccucc gagaagcuca acaaucugcu ggaaggcaac      780

gauucagaca augaucucag cuuagaggac uuuugaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10850
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10850
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaacagagc caccaaguuc cuggagagca ucaagggcaa guucaccagc      180

cccaaggacc ccaagaagaa ggacagcauc aucagcguga acagcaucga caucgaggug      240

accaaggaga gccccaucac cagcaacagc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag agaaagcccc uggugagcuu caaggaggac      360

cccaccccca gcgacaaccc cuucagcaag cuguacaagg agaccaucga gaccuucgac      420

aacaacgagg aggagagcag cuacagcuac gaggagauca acgaccagac caacgacaac      480

aucaccgcca gacuggacag aaucgacgag aagcugagcg agauccuggg caugcugcac      540

acccuggugg uggccagcgc cggccccacc agcgccagag acggcaucag agacgccaug      600

aucggccuga gagaggagau gaucgagaag aucagaaccg aggcccugau gaccaacgac      660

agacuggagg ccauggccag acugagaaac gaggagagcg agaagauggc caaggacacc      720

agcgacgagg ugagccugaa ccccaccagc gagaagcuga acaaccugcu ggagggcaac      780

gacagcgaca acgaccugag ccuggaggac uucugaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10851
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10851
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc caccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu aucagcguga acuccauuga uaucgagguc      240

acgaaagaau cucccauuac cagcaauucc acaaucauca acccuaccaa ugagacagac      300

gauaccgcgg gaaacaagcc caauuaccag cggaaaccuc ucguuucuuu caaggaggac      360

cccacaccua gcgauaaccc guuuuccaaa cuguauaagg aaaccauuga gacguucgac      420

aauaacgaag aggagagcuc uuacuccuau gaagagauca augaucaaac caacgacaau      480

auuacagcuc gccuugauag aaucgacgaa aagcugagcg agauucucgg caugcugcau      540

acccuugugg uggccucugc cgggcccaca uccgcucggg auggaauccg cgacgccaug      600

auuggccuga gagaagagau gaucgagaaa auccggaccg aagcucucau gacgaacgac      660

cgccuggagg ccauggcgag acugcggaau gaagagagcg aaaagauggc caaagauaca      720

ucugacgagg ucucccucaa cccuaccagc gagaagcuga acaaucuucu ggaagggaac      780

gauuccgaca augaucucuc ucuggaggac uuuugaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10852
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10852
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcaccaga auuucacgga      120

gaagacgcaa acaacagagc aacaaaauuc uuagaaucaa ucaaaggaaa auucacaagc      180

ccaaaagacc caaaaaaaaa agacucaaua auaagcguaa acucaauaga cauagaagua      240

acaaaagaaa gcccaauaac aagcaacagc acaauaauaa acccaacaaa cgaaacagau      300

gacacagcug gaaauaaacc aaacuaccaa agaaaacccc uagucagcuu caaagaagac      360

cccacaccau cagacaaccc auucagcaaa cuauauaaag aaacaauaga aacauuugac      420

aacaacgaag aagaaucauc auacucauac gaagaaauaa acgaccaaac aaacgacaac      480

auaaccgcaa gauuagacag aauagaugaa aaacuaucag aaauacuagg aaugcuacac      540

acauuaguag uagcaagcgc aggaccaaca ucagcaagag acggaauaag agacgcaaug      600

auaggacuca gagaagaaau gauagaaaaa auaagaacag aagcacuaau gacaaacgac      660

agauuagaag caauggcaag acuaagaaau gaagaaucgg aaaaaauggc aaaagacaca      720

ucagacgaag uaagccuaaa cccaacauca gaaaaauuaa auaaccuacu agaaggaaac      780

gacagcgaca acgacuuauc acuagaagac uucuaaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10853
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design e-6 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10853
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcgcccga guuccacggc      120

gaggacgcga acaaccgcgc gacaaaguuc cuagaaucaa ucaagggcaa auucacgagc      180

ccgaaagacc ccaagaaaaa ggacucaauc auaagcguga acucgaucga caucgagguc      240

acgaaagaga gcccgaucac aagcaacagc accauaauaa acccgaccaa cgaaacagac      300

gacaccgcgg gcaacaaacc gaacuaccaa agaaaaccgc ucgugagcuu caaagaagac      360

ccgaccccaa gcgacaaccc guucucaaaa cuauacaagg aaacgaucga gaccuucgac      420

aacaacgagg aagagagcuc guacucguac gaggaaauaa acgaccaaac aaacgacaac      480

auaaccgcac gccuagacag gaucgacgaa aaacucucgg aaauacucgg gaugcuacac      540

acgcucgugg ucgcgagcgc aggcccgacc ucggccaggg acggcaucag ggacgcaaug      600

auaggccugc gagaggaaau gaucgagaaa auacgcaccg aagcacucau gaccaacgac      660

agacucgaag ccauggccag gcucaggaac gaagaauccg aaaagauggc gaaagacacc      720

ucggacgagg ucucgcucaa ccccacgagc gagaaacuga acaaccuacu ggaagggaac      780

gacagcgaca acgaccuuuc ccucgaggac uucugaggac uaguacuggc ugcaucuccc      840

uuuccucugu ccuccauccu ucucccagga uggugaaggg ggaccuggua cccagugauc      900

cccaccccag gauccuaaau caugacuuac cugcuaauaa aaacucauug gaaaagugag      960

aagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1080

agagccacca gaauu                                                      1095


<210>  10854
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10854
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaagu uugcuccuga auuccaugga      120

gaagaugcaa acaacagggc uacuaaauuc cuagaaucaa uaaagggcaa auucacauca      180

cccaaagauc ccaagaaaaa agauaguauc auaucuguca acucaauaga uauagaagua      240

accaaagaaa gcccuauaac aucaaauuca acuauuauca acccaacaaa ugagacagau      300

gauacugcag ggaacaagcc caauuaucaa agaaaaccuc uaguaaguuu caaagaagac      360

ccuacaccaa gugauaaucc cuuuucuaaa cuauacaaag aaaccauaga aacauuugau      420

aacaaugaag aagaauccag cuauucauac gaagaaauaa augaucagac aaacgauaau      480

auaacagcaa gauuagauag gauugaugaa aaauuaagug aaauacuagg aaugcuucac      540

acauuaguag uggcaagugc aggaccuaca ucugcucggg augguauaag agaugccaug      600

auugguuuaa gagaagaaau gauagaaaaa aucagaacug aagcauuaau gaccaaugac      660

agauuagaag cuauggcaag acucaggaau gaggaaagug aaaagauggc aaaagacaca      720

ucagaugaag ugucucucaa uccaacauca gagaaauuga acaaccuauu ggaagggaau      780

gauagugaca augaucuauc acuugaagau uucugaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10855
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10855
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc gaccaaguuc cuggagagca ucaaggggaa guucaccucc      180

ccgaaggacc ccaagaagaa ggacagcauc aucuccguga acagcaucga caucgagguc      240

acgaaggagu cccccaucac cagcaacucc accaucauca accccaccaa cgagacggac      300

gacaccgccg gcaacaagcc gaacuaccag cggaagcccc ucgugagcuu caaggaggac      360

cccacccccu ccgacaaccc guucagcaag cuguacaagg agaccaucga gacguucgac      420

aacaacgagg aggaguccag cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccuggaccg gaucgacgag aagcucagcg agauccuggg gaugcugcac      540

acccucgugg ucgccuccgc cggccccacg agcgcgcgcg acgggauccg ggacgccaug      600

aucggccugc gcgaggagau gaucgagaag auccggaccg aggcccugau gaccaacgac      660

cgccucgagg ccauggcgcg gcugcgcaac gaggaguccg agaagauggc caaggacacc      720

agcgacgagg ugucccugaa ccccacgagc gagaagcuca acaaccugcu ggagggcaac      780

gacagcgaca acgaccucuc ccuggaggac uucugaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10856
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10856
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc caccaaguuc cucgagucca ucaagggcaa guucaccucc      180

cccaaggacc ccaagaagaa ggacuccauc aucuccguca acuccaucga caucgagguc      240

accaaggagu cccccaucac cuccaacucc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag cgcaagcccc ucgucuccuu caaggaggac      360

cccacccccu ccgacaaccc cuucuccaag cucuacaagg agaccaucga gaccuucgac      420

aacaacgagg aggaguccuc cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccucgaccg caucgacgag aagcucuccg agauccucgg caugcuccac      540

acccucgucg ucgccuccgc cggccccacc uccgcccgcg acggcauccg cgacgccaug      600

aucggccucc gcgaggagau gaucgagaag auccgcaccg aggcccucau gaccaacgac      660

cgccucgagg ccauggcccg ccuccgcaac gaggaguccg agaagauggc caaggacacc      720

uccgacgagg ucucccucaa ccccaccucc gagaagcuca acaaccuccu cgagggcaac      780

gacuccgaca acgaccucuc ccucgaggac uucugaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10857
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10857
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc aaccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu auaucaguga acaguaucga uauugagguc      240

acuaaagaaa gcccaaucac guccaauucu accauuauca accccacaaa ugagacugac      300

gauaccgccg gaaacaagcc uaauuaccag aggaaaccac ucguuucguu caaggaggac      360

cccacaccuu cagauaaccc auuuagcaaa cuuuauaagg aaaccauaga gacuuucgac      420

aauaacgaag aggagaguuc cuacucuuau gaagagauca augaucaaac aaacgacaau      480

auuaccgcgc ggcuggaucg caucgacgaa aaguugagcg agauuuuagg uaugcugcau      540

acgcuagugg uagcuuccgc cggccccacu ucagcacgag augggauccg ugacgccaug      600

auaggacuca gagaagagau gauugagaaa aucaggaccg aagcucugau gacaaacgac      660

cggcuugagg caauggcccg ccugagaaau gaagagagug aaaagauggc uaaagauacu      720

agcgacgagg ugucuuugaa cccuaccucc gagaagcuca acaaucugcu ggaaggcaac      780

gauucagaca augaucucag cuuagaggac uuuugaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10858
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10858
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaacagagc caccaaguuc cuggagagca ucaagggcaa guucaccagc      180

cccaaggacc ccaagaagaa ggacagcauc aucagcguga acagcaucga caucgaggug      240

accaaggaga gccccaucac cagcaacagc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag agaaagcccc uggugagcuu caaggaggac      360

cccaccccca gcgacaaccc cuucagcaag cuguacaagg agaccaucga gaccuucgac      420

aacaacgagg aggagagcag cuacagcuac gaggagauca acgaccagac caacgacaac      480

aucaccgcca gacuggacag aaucgacgag aagcugagcg agauccuggg caugcugcac      540

acccuggugg uggccagcgc cggccccacc agcgccagag acggcaucag agacgccaug      600

aucggccuga gagaggagau gaucgagaag aucagaaccg aggcccugau gaccaacgac      660

agacuggagg ccauggccag acugagaaac gaggagagcg agaagauggc caaggacacc      720

agcgacgagg ugagccugaa ccccaccagc gagaagcuga acaaccugcu ggagggcaac      780

gacagcgaca acgaccugag ccuggaggac uucugaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10859
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10859
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc caccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu aucagcguga acuccauuga uaucgagguc      240

acgaaagaau cucccauuac cagcaauucc acaaucauca acccuaccaa ugagacagac      300

gauaccgcgg gaaacaagcc caauuaccag cggaaaccuc ucguuucuuu caaggaggac      360

cccacaccua gcgauaaccc guuuuccaaa cuguauaagg aaaccauuga gacguucgac      420

aauaacgaag aggagagcuc uuacuccuau gaagagauca augaucaaac caacgacaau      480

auuacagcuc gccuugauag aaucgacgaa aagcugagcg agauucucgg caugcugcau      540

acccuugugg uggccucugc cgggcccaca uccgcucggg auggaauccg cgacgccaug      600

auuggccuga gagaagagau gaucgagaaa auccggaccg aagcucucau gacgaacgac      660

cgccuggagg ccauggcgag acugcggaau gaagagagcg aaaagauggc caaagauaca      720

ucugacgagg ucucccucaa cccuaccagc gagaagcuga acaaucuucu ggaagggaac      780

gauuccgaca augaucucuc ucuggaggac uuuugaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10860
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10860
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcaccaga auuucacgga      120

gaagacgcaa acaacagagc aacaaaauuc uuagaaucaa ucaaaggaaa auucacaagc      180

ccaaaagacc caaaaaaaaa agacucaaua auaagcguaa acucaauaga cauagaagua      240

acaaaagaaa gcccaauaac aagcaacagc acaauaauaa acccaacaaa cgaaacagau      300

gacacagcug gaaauaaacc aaacuaccaa agaaaacccc uagucagcuu caaagaagac      360

cccacaccau cagacaaccc auucagcaaa cuauauaaag aaacaauaga aacauuugac      420

aacaacgaag aagaaucauc auacucauac gaagaaauaa acgaccaaac aaacgacaac      480

auaaccgcaa gauuagacag aauagaugaa aaacuaucag aaauacuagg aaugcuacac      540

acauuaguag uagcaagcgc aggaccaaca ucagcaagag acggaauaag agacgcaaug      600

auaggacuca gagaagaaau gauagaaaaa auaagaacag aagcacuaau gacaaacgac      660

agauuagaag caauggcaag acuaagaaau gaagaaucgg aaaaaauggc aaaagacaca      720

ucagacgaag uaagccuaaa cccaacauca gaaaaauuaa auaaccuacu agaaggaaac      780

gacagcgaca acgacuuauc acuagaagac uucuaaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10861
<211>  1311
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10861
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcgcccga guuccacggc      120

gaggacgcga acaaccgcgc gacaaaguuc cuagaaucaa ucaagggcaa auucacgagc      180

ccgaaagacc ccaagaaaaa ggacucaauc auaagcguga acucgaucga caucgagguc      240

acgaaagaga gcccgaucac aagcaacagc accauaauaa acccgaccaa cgaaacagac      300

gacaccgcgg gcaacaaacc gaacuaccaa agaaaaccgc ucgugagcuu caaagaagac      360

ccgaccccaa gcgacaaccc guucucaaaa cuauacaagg aaacgaucga gaccuucgac      420

aacaacgagg aagagagcuc guacucguac gaggaaauaa acgaccaaac aaacgacaac      480

auaaccgcac gccuagacag gaucgacgaa aaacucucgg aaauacucgg gaugcuacac      540

acgcucgugg ucgcgagcgc aggcccgacc ucggccaggg acggcaucag ggacgcaaug      600

auaggccugc gagaggaaau gaucgagaaa auacgcaccg aagcacucau gaccaacgac      660

agacucgaag ccauggccag gcucaggaac gaagaauccg aaaagauggc gaaagacacc      720

ucggacgagg ucucgcucaa ccccacgagc gagaaacuga acaaccuacu ggaagggaac      780

gacagcgaca acgaccuuuc ccucgaggac uucugaggac uagugaaggg aacacccaaa      840

uuuaauucag ccuuaagcac aauuaauuaa gagugaaacg uaauuguaca agcaguuggu      900

cacccaccau agggcaugau caacaccgca accuuuccuu uuucccccag ugauucugaa      960

aaaccccucu ucccuucagc uugcuuagau guuccaaauu uaguaagcuu aaggcggccu     1020

acagaagaaa aagaaaaaaa aggccacaaa aguucccucu cacuuucagu aaauaaaaua     1080

aaagcagcaa cagaaauaaa gaaauaaaug aaauucaaaa ugaaauaaau auuguguugu     1140

gcagcauuaa aaaaucaaua aaaauuaaaa augagcaaga ucuaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1260

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1311


<210>  10862
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10862
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaagu uugcuccuga auuccaugga      120

gaagaugcaa acaacagggc uacuaaauuc cuagaaucaa uaaagggcaa auucacauca      180

cccaaagauc ccaagaaaaa agauaguauc auaucuguca acucaauaga uauagaagua      240

accaaagaaa gcccuauaac aucaaauuca acuauuauca acccaacaaa ugagacagau      300

gauacugcag ggaacaagcc caauuaucaa agaaaaccuc uaguaaguuu caaagaagac      360

ccuacaccaa gugauaaucc cuuuucuaaa cuauacaaag aaaccauaga aacauuugau      420

aacaaugaag aagaauccag cuauucauac gaagaaauaa augaucagac aaacgauaau      480

auaacagcaa gauuagauag gauugaugaa aaauuaagug aaauacuagg aaugcuucac      540

acauuaguag uggcaagugc aggaccuaca ucugcucggg augguauaag agaugccaug      600

auugguuuaa gagaagaaau gauagaaaaa aucagaacug aagcauuaau gaccaaugac      660

agauuagaag cuauggcaag acucaggaau gaggaaagug aaaagauggc aaaagacaca      720

ucagaugaag ugucucucaa uccaacauca gagaaauuga acaaccuauu ggaagggaau      780

gauagugaca augaucuauc acuugaagau uucugaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10863
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10863
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc gaccaaguuc cuggagagca ucaaggggaa guucaccucc      180

ccgaaggacc ccaagaagaa ggacagcauc aucuccguga acagcaucga caucgagguc      240

acgaaggagu cccccaucac cagcaacucc accaucauca accccaccaa cgagacggac      300

gacaccgccg gcaacaagcc gaacuaccag cggaagcccc ucgugagcuu caaggaggac      360

cccacccccu ccgacaaccc guucagcaag cuguacaagg agaccaucga gacguucgac      420

aacaacgagg aggaguccag cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccuggaccg gaucgacgag aagcucagcg agauccuggg gaugcugcac      540

acccucgugg ucgccuccgc cggccccacg agcgcgcgcg acgggauccg ggacgccaug      600

aucggccugc gcgaggagau gaucgagaag auccggaccg aggcccugau gaccaacgac      660

cgccucgagg ccauggcgcg gcugcgcaac gaggaguccg agaagauggc caaggacacc      720

agcgacgagg ugucccugaa ccccacgagc gagaagcuca acaaccugcu ggagggcaac      780

gacagcgaca acgaccucuc ccuggaggac uucugaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10864
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10864
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaaccgcgc caccaaguuc cucgagucca ucaagggcaa guucaccucc      180

cccaaggacc ccaagaagaa ggacuccauc aucuccguca acuccaucga caucgagguc      240

accaaggagu cccccaucac cuccaacucc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag cgcaagcccc ucgucuccuu caaggaggac      360

cccacccccu ccgacaaccc cuucuccaag cucuacaagg agaccaucga gaccuucgac      420

aacaacgagg aggaguccuc cuacuccuac gaggagauca acgaccagac caacgacaac      480

aucaccgccc gccucgaccg caucgacgag aagcucuccg agauccucgg caugcuccac      540

acccucgucg ucgccuccgc cggccccacc uccgcccgcg acggcauccg cgacgccaug      600

aucggccucc gcgaggagau gaucgagaag auccgcaccg aggcccucau gaccaacgac      660

cgccucgagg ccauggcccg ccuccgcaac gaggaguccg agaagauggc caaggacacc      720

uccgacgagg ucucccucaa ccccaccucc gagaagcuca acaaccuccu cgagggcaac      780

gacuccgaca acgaccucuc ccucgaggac uucugaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10865
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10865
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc aaccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu auaucaguga acaguaucga uauugagguc      240

acuaaagaaa gcccaaucac guccaauucu accauuauca accccacaaa ugagacugac      300

gauaccgccg gaaacaagcc uaauuaccag aggaaaccac ucguuucguu caaggaggac      360

cccacaccuu cagauaaccc auuuagcaaa cuuuauaagg aaaccauaga gacuuucgac      420

aauaacgaag aggagaguuc cuacucuuau gaagagauca augaucaaac aaacgacaau      480

auuaccgcgc ggcuggaucg caucgacgaa aaguugagcg agauuuuagg uaugcugcau      540

acgcuagugg uagcuuccgc cggccccacu ucagcacgag augggauccg ugacgccaug      600

auaggacuca gagaagagau gauugagaaa aucaggaccg aagcucugau gacaaacgac      660

cggcuugagg caauggcccg ccugagaaau gaagagagug aaaagauggc uaaagauacu      720

agcgacgagg ugucuuugaa cccuaccucc gagaagcuca acaaucugcu ggaaggcaac      780

gauucagaca augaucucag cuuagaggac uuuugaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10866
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10866
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga guuccacggc      120

gaggacgcca acaacagagc caccaaguuc cuggagagca ucaagggcaa guucaccagc      180

cccaaggacc ccaagaagaa ggacagcauc aucagcguga acagcaucga caucgaggug      240

accaaggaga gccccaucac cagcaacagc accaucauca accccaccaa cgagaccgac      300

gacaccgccg gcaacaagcc caacuaccag agaaagcccc uggugagcuu caaggaggac      360

cccaccccca gcgacaaccc cuucagcaag cuguacaagg agaccaucga gaccuucgac      420

aacaacgagg aggagagcag cuacagcuac gaggagauca acgaccagac caacgacaac      480

aucaccgcca gacuggacag aaucgacgag aagcugagcg agauccuggg caugcugcac      540

acccuggugg uggccagcgc cggccccacc agcgccagag acggcaucag agacgccaug      600

aucggccuga gagaggagau gaucgagaag aucagaaccg aggcccugau gaccaacgac      660

agacuggagg ccauggccag acugagaaac gaggagagcg agaagauggc caaggacacc      720

agcgacgagg ugagccugaa ccccaccagc gagaagcuga acaaccugcu ggagggcaac      780

gacagcgaca acgaccugag ccuggaggac uucugaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10867
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10867
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggagaagu ucgcccccga auuucacggc      120

gaggacgcua acaauagagc caccaaauuc cuggaaagca ucaaggggaa auuuacaucc      180

ccuaaggauc cgaaaaagaa ggacucuauu aucagcguga acuccauuga uaucgagguc      240

acgaaagaau cucccauuac cagcaauucc acaaucauca acccuaccaa ugagacagac      300

gauaccgcgg gaaacaagcc caauuaccag cggaaaccuc ucguuucuuu caaggaggac      360

cccacaccua gcgauaaccc guuuuccaaa cuguauaagg aaaccauuga gacguucgac      420

aauaacgaag aggagagcuc uuacuccuau gaagagauca augaucaaac caacgacaau      480

auuacagcuc gccuugauag aaucgacgaa aagcugagcg agauucucgg caugcugcau      540

acccuugugg uggccucugc cgggcccaca uccgcucggg auggaauccg cgacgccaug      600

auuggccuga gagaagagau gaucgagaaa auccggaccg aagcucucau gacgaacgac      660

cgccuggagg ccauggcgag acugcggaau gaagagagcg aaaagauggc caaagauaca      720

ucugacgagg ucucccucaa cccuaccagc gagaagcuga acaaucuucu ggaagggaac      780

gauuccgaca augaucucuc ucuggaggac uuuugaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10868
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10868
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcaccaga auuucacgga      120

gaagacgcaa acaacagagc aacaaaauuc uuagaaucaa ucaaaggaaa auucacaagc      180

ccaaaagacc caaaaaaaaa agacucaaua auaagcguaa acucaauaga cauagaagua      240

acaaaagaaa gcccaauaac aagcaacagc acaauaauaa acccaacaaa cgaaacagau      300

gacacagcug gaaauaaacc aaacuaccaa agaaaacccc uagucagcuu caaagaagac      360

cccacaccau cagacaaccc auucagcaaa cuauauaaag aaacaauaga aacauuugac      420

aacaacgaag aagaaucauc auacucauac gaagaaauaa acgaccaaac aaacgacaac      480

auaaccgcaa gauuagacag aauagaugaa aaacuaucag aaauacuagg aaugcuacac      540

acauuaguag uagcaagcgc aggaccaaca ucagcaagag acggaauaag agacgcaaug      600

auaggacuca gagaagaaau gauagaaaaa auaagaacag aagcacuaau gacaaacgac      660

agauuagaag caauggcaag acuaagaaau gaagaaucgg aaaaaauggc aaaagacaca      720

ucagacgaag uaagccuaaa cccaacauca gaaaaauuaa auaaccuacu agaaggaaac      780

gacagcgaca acgacuuauc acuagaagac uucuaaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10869
<211>  1091
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10869
gggagagcgg cucggccauu uugucccagu caguccggag gcugcggcug cagaaguacc       60

gccugcggag uaacugcaaa gaagcuuacc auggaaaaau ucgcgcccga guuccacggc      120

gaggacgcga acaaccgcgc gacaaaguuc cuagaaucaa ucaagggcaa auucacgagc      180

ccgaaagacc ccaagaaaaa ggacucaauc auaagcguga acucgaucga caucgagguc      240

acgaaagaga gcccgaucac aagcaacagc accauaauaa acccgaccaa cgaaacagac      300

gacaccgcgg gcaacaaacc gaacuaccaa agaaaaccgc ucgugagcuu caaagaagac      360

ccgaccccaa gcgacaaccc guucucaaaa cuauacaagg aaacgaucga gaccuucgac      420

aacaacgagg aagagagcuc guacucguac gaggaaauaa acgaccaaac aaacgacaac      480

auaaccgcac gccuagacag gaucgacgaa aaacucucgg aaauacucgg gaugcuacac      540

acgcucgugg ucgcgagcgc aggcccgacc ucggccaggg acggcaucag ggacgcaaug      600

auaggccugc gagaggaaau gaucgagaaa auacgcaccg aagcacucau gaccaacgac      660

agacucgaag ccauggccag gcucaggaac gaagaauccg aaaagauggc gaaagacacc      720

ucggacgagg ucucgcucaa ccccacgagc gagaaacuga acaaccuacu ggaagggaac      780

gacagcgaca acgaccuuuc ccucgaggac uucugaggac uaguggaagc auuuuccugg      840

cugauuaaaa gaaauuacuc agcuaugguc aucuguuccu guuagaaggc uaugcagcau      900

auuauauacu augcgcaugu uaugaaaugc auaauaaaaa auuuuaaaaa aucuaaaaga      960

ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag     1080

ccaccagaau u                                                          1091


<210>  10870
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10870
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca      120

acagggcuac uaaauuccua gaaucaauaa agggcaaauu cacaucaccc aaagauccca      180

agaaaaaaga uaguaucaua ucugucaacu caauagauau agaaguaacc aaagaaagcc      240

cuauaacauc aaauucaacu auuaucaacc caacaaauga gacagaugau acugcaggga      300

acaagcccaa uuaucaaaga aaaccucuag uaaguuucaa agaagacccu acaccaagug      360

auaaucccuu uucuaaacua uacaaagaaa ccauagaaac auuugauaac aaugaagaag      420

aauccagcua uucauacgaa gaaauaaaug aucagacaaa cgauaauaua acagcaagau      480

uagauaggau ugaugaaaaa uuaagugaaa uacuaggaau gcuucacaca uuaguagugg      540

caagugcagg accuacaucu gcucgggaug guauaagaga ugccaugauu gguuuaagag      600

aagaaaugau agaaaaaauc agaacugaag cauuaaugac caaugacaga uuagaagcua      660

uggcaagacu caggaaugag gaaagugaaa agauggcaaa agacacauca gaugaagugu      720

cucucaaucc aacaucagag aaauugaaca accuauugga agggaaugau agugacaaug      780

aucuaucacu ugaagauuuc ugaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10871
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10871
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgcgac caaguuccug gagagcauca aggggaaguu caccuccccg aaggacccca      180

agaagaagga cagcaucauc uccgugaaca gcaucgacau cgaggucacg aaggaguccc      240

ccaucaccag caacuccacc aucaucaacc ccaccaacga gacggacgac accgccggca      300

acaagccgaa cuaccagcgg aagccccucg ugagcuucaa ggaggacccc acccccuccg      360

acaacccguu cagcaagcug uacaaggaga ccaucgagac guucgacaac aacgaggagg      420

aguccagcua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

uggaccggau cgacgagaag cucagcgaga uccuggggau gcugcacacc cucguggucg      540

ccuccgccgg ccccacgagc gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg      600

aggagaugau cgagaagauc cggaccgagg cccugaugac caacgaccgc cucgaggcca      660

uggcgcggcu gcgcaacgag gaguccgaga agauggccaa ggacaccagc gacgaggugu      720

cccugaaccc cacgagcgag aagcucaaca accugcugga gggcaacgac agcgacaacg      780

accucucccu ggaggacuuc ugaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10872
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10872
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgccac caaguuccuc gaguccauca agggcaaguu caccuccccc aaggacccca      180

agaagaagga cuccaucauc uccgucaacu ccaucgacau cgaggucacc aaggaguccc      240

ccaucaccuc caacuccacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagcgc aagccccucg ucuccuucaa ggaggacccc acccccuccg      360

acaaccccuu cuccaagcuc uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

aguccuccua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

ucgaccgcau cgacgagaag cucuccgaga uccucggcau gcuccacacc cucgucgucg      540

ccuccgccgg ccccaccucc gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg      600

aggagaugau cgagaagauc cgcaccgagg cccucaugac caacgaccgc cucgaggcca      660

uggcccgccu ccgcaacgag gaguccgaga agauggccaa ggacaccucc gacgaggucu      720

cccucaaccc caccuccgag aagcucaaca accuccucga gggcaacgac uccgacaacg      780

accucucccu cgaggacuuc ugaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10873
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10873
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagcaac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuaua ucagugaaca guaucgauau ugaggucacu aaagaaagcc      240

caaucacguc caauucuacc auuaucaacc ccacaaauga gacugacgau accgccggaa      300

acaagccuaa uuaccagagg aaaccacucg uuucguucaa ggaggacccc acaccuucag      360

auaacccauu uagcaaacuu uauaaggaaa ccauagagac uuucgacaau aacgaagagg      420

agaguuccua cucuuaugaa gagaucaaug aucaaacaaa cgacaauauu accgcgcggc      480

uggaucgcau cgacgaaaag uugagcgaga uuuuagguau gcugcauacg cuagugguag      540

cuuccgccgg ccccacuuca gcacgagaug ggauccguga cgccaugaua ggacucagag      600

aagagaugau ugagaaaauc aggaccgaag cucugaugac aaacgaccgg cuugaggcaa      660

uggcccgccu gagaaaugaa gagagugaaa agauggcuaa agauacuagc gacgaggugu      720

cuuugaaccc uaccuccgag aagcucaaca aucugcugga aggcaacgau ucagacaaug      780

aucucagcuu agaggacuuu ugaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10874
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10874
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

acagagccac caaguuccug gagagcauca agggcaaguu caccagcccc aaggacccca      180

agaagaagga cagcaucauc agcgugaaca gcaucgacau cgaggugacc aaggagagcc      240

ccaucaccag caacagcacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagaga aagccccugg ugagcuucaa ggaggacccc acccccagcg      360

acaaccccuu cagcaagcug uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

agagcagcua cagcuacgag gagaucaacg accagaccaa cgacaacauc accgccagac      480

uggacagaau cgacgagaag cugagcgaga uccugggcau gcugcacacc cugguggugg      540

ccagcgccgg ccccaccagc gccagagacg gcaucagaga cgccaugauc ggccugagag      600

aggagaugau cgagaagauc agaaccgagg cccugaugac caacgacaga cuggaggcca      660

uggccagacu gagaaacgag gagagcgaga agauggccaa ggacaccagc gacgagguga      720

gccugaaccc caccagcgag aagcugaaca accugcugga gggcaacgac agcgacaacg      780

accugagccu ggaggacuuc ugaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10875
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10875
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagccac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuauc agcgugaacu ccauugauau cgaggucacg aaagaaucuc      240

ccauuaccag caauuccaca aucaucaacc cuaccaauga gacagacgau accgcgggaa      300

acaagcccaa uuaccagcgg aaaccucucg uuucuuucaa ggaggacccc acaccuagcg      360

auaacccguu uuccaaacug uauaaggaaa ccauugagac guucgacaau aacgaagagg      420

agagcucuua cuccuaugaa gagaucaaug aucaaaccaa cgacaauauu acagcucgcc      480

uugauagaau cgacgaaaag cugagcgaga uucucggcau gcugcauacc cuuguggugg      540

ccucugccgg gcccacaucc gcucgggaug gaauccgcga cgccaugauu ggccugagag      600

aagagaugau cgagaaaauc cggaccgaag cucucaugac gaacgaccgc cuggaggcca      660

uggcgagacu gcggaaugaa gagagcgaaa agauggccaa agauacaucu gacgaggucu      720

cccucaaccc uaccagcgag aagcugaaca aucuucugga agggaacgau uccgacaaug      780

aucucucucu ggaggacuuu ugaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10876
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10876
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg caccagaauu ucacggagaa gacgcaaaca      120

acagagcaac aaaauucuua gaaucaauca aaggaaaauu cacaagccca aaagacccaa      180

aaaaaaaaga cucaauaaua agcguaaacu caauagacau agaaguaaca aaagaaagcc      240

caauaacaag caacagcaca auaauaaacc caacaaacga aacagaugac acagcuggaa      300

auaaaccaaa cuaccaaaga aaaccccuag ucagcuucaa agaagacccc acaccaucag      360

acaacccauu cagcaaacua uauaaagaaa caauagaaac auuugacaac aacgaagaag      420

aaucaucaua cucauacgaa gaaauaaacg accaaacaaa cgacaacaua accgcaagau      480

uagacagaau agaugaaaaa cuaucagaaa uacuaggaau gcuacacaca uuaguaguag      540

caagcgcagg accaacauca gcaagagacg gaauaagaga cgcaaugaua ggacucagag      600

aagaaaugau agaaaaaaua agaacagaag cacuaaugac aaacgacaga uuagaagcaa      660

uggcaagacu aagaaaugaa gaaucggaaa aaauggcaaa agacacauca gacgaaguaa      720

gccuaaaccc aacaucagaa aaauuaaaua accuacuaga aggaaacgac agcgacaacg      780

acuuaucacu agaagacuuc uaaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10877
<211>  1082
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10877
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca      120

accgcgcgac aaaguuccua gaaucaauca agggcaaauu cacgagcccg aaagacccca      180

agaaaaagga cucaaucaua agcgugaacu cgaucgacau cgaggucacg aaagagagcc      240

cgaucacaag caacagcacc auaauaaacc cgaccaacga aacagacgac accgcgggca      300

acaaaccgaa cuaccaaaga aaaccgcucg ugagcuucaa agaagacccg accccaagcg      360

acaacccguu cucaaaacua uacaaggaaa cgaucgagac cuucgacaac aacgaggaag      420

agagcucgua cucguacgag gaaauaaacg accaaacaaa cgacaacaua accgcacgcc      480

uagacaggau cgacgaaaaa cucucggaaa uacucgggau gcuacacacg cucguggucg      540

cgagcgcagg cccgaccucg gccagggacg gcaucaggga cgcaaugaua ggccugcgag      600

aggaaaugau cgagaaaaua cgcaccgaag cacucaugac caacgacaga cucgaagcca      660

uggccaggcu caggaacgaa gaauccgaaa agauggcgaa agacaccucg gacgaggucu      720

cgcucaaccc cacgagcgag aaacugaaca accuacugga agggaacgac agcgacaacg      780

accuuucccu cgaggacuuc ugaggacuag uacuggcugc aucucccuuu ccucuguccu      840

ccauccuucu cccaggaugg ugaaggggga ccugguaccc agugaucccc accccaggau      900

ccuaaaucau gacuuaccug cuaauaaaaa cucauuggaa aagugagaag aucuaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug     1020

cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa     1080

uu                                                                    1082


<210>  10878
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10878
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca      120

acagggcuac uaaauuccua gaaucaauaa agggcaaauu cacaucaccc aaagauccca      180

agaaaaaaga uaguaucaua ucugucaacu caauagauau agaaguaacc aaagaaagcc      240

cuauaacauc aaauucaacu auuaucaacc caacaaauga gacagaugau acugcaggga      300

acaagcccaa uuaucaaaga aaaccucuag uaaguuucaa agaagacccu acaccaagug      360

auaaucccuu uucuaaacua uacaaagaaa ccauagaaac auuugauaac aaugaagaag      420

aauccagcua uucauacgaa gaaauaaaug aucagacaaa cgauaauaua acagcaagau      480

uagauaggau ugaugaaaaa uuaagugaaa uacuaggaau gcuucacaca uuaguagugg      540

caagugcagg accuacaucu gcucgggaug guauaagaga ugccaugauu gguuuaagag      600

aagaaaugau agaaaaaauc agaacugaag cauuaaugac caaugacaga uuagaagcua      660

uggcaagacu caggaaugag gaaagugaaa agauggcaaa agacacauca gaugaagugu      720

cucucaaucc aacaucagag aaauugaaca accuauugga agggaaugau agugacaaug      780

aucuaucacu ugaagauuuc ugaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10879
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10879
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgcgac caaguuccug gagagcauca aggggaaguu caccuccccg aaggacccca      180

agaagaagga cagcaucauc uccgugaaca gcaucgacau cgaggucacg aaggaguccc      240

ccaucaccag caacuccacc aucaucaacc ccaccaacga gacggacgac accgccggca      300

acaagccgaa cuaccagcgg aagccccucg ugagcuucaa ggaggacccc acccccuccg      360

acaacccguu cagcaagcug uacaaggaga ccaucgagac guucgacaac aacgaggagg      420

aguccagcua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

uggaccggau cgacgagaag cucagcgaga uccuggggau gcugcacacc cucguggucg      540

ccuccgccgg ccccacgagc gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg      600

aggagaugau cgagaagauc cggaccgagg cccugaugac caacgaccgc cucgaggcca      660

uggcgcggcu gcgcaacgag gaguccgaga agauggccaa ggacaccagc gacgaggugu      720

cccugaaccc cacgagcgag aagcucaaca accugcugga gggcaacgac agcgacaacg      780

accucucccu ggaggacuuc ugaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10880
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10880
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

accgcgccac caaguuccuc gaguccauca agggcaaguu caccuccccc aaggacccca      180

agaagaagga cuccaucauc uccgucaacu ccaucgacau cgaggucacc aaggaguccc      240

ccaucaccuc caacuccacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagcgc aagccccucg ucuccuucaa ggaggacccc acccccuccg      360

acaaccccuu cuccaagcuc uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

aguccuccua cuccuacgag gagaucaacg accagaccaa cgacaacauc accgcccgcc      480

ucgaccgcau cgacgagaag cucuccgaga uccucggcau gcuccacacc cucgucgucg      540

ccuccgccgg ccccaccucc gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg      600

aggagaugau cgagaagauc cgcaccgagg cccucaugac caacgaccgc cucgaggcca      660

uggcccgccu ccgcaacgag gaguccgaga agauggccaa ggacaccucc gacgaggucu      720

cccucaaccc caccuccgag aagcucaaca accuccucga gggcaacgac uccgacaacg      780

accucucccu cgaggacuuc ugaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10881
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10881
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagcaac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuaua ucagugaaca guaucgauau ugaggucacu aaagaaagcc      240

caaucacguc caauucuacc auuaucaacc ccacaaauga gacugacgau accgccggaa      300

acaagccuaa uuaccagagg aaaccacucg uuucguucaa ggaggacccc acaccuucag      360

auaacccauu uagcaaacuu uauaaggaaa ccauagagac uuucgacaau aacgaagagg      420

agaguuccua cucuuaugaa gagaucaaug aucaaacaaa cgacaauauu accgcgcggc      480

uggaucgcau cgacgaaaag uugagcgaga uuuuagguau gcugcauacg cuagugguag      540

cuuccgccgg ccccacuuca gcacgagaug ggauccguga cgccaugaua ggacucagag      600

aagagaugau ugagaaaauc aggaccgaag cucugaugac aaacgaccgg cuugaggcaa      660

uggcccgccu gagaaaugaa gagagugaaa agauggcuaa agauacuagc gacgaggugu      720

cuuugaaccc uaccuccgag aagcucaaca aucugcugga aggcaacgau ucagacaaug      780

aucucagcuu agaggacuuu ugaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10882
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10882
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaguu ccacggcgag gacgccaaca      120

acagagccac caaguuccug gagagcauca agggcaaguu caccagcccc aaggacccca      180

agaagaagga cagcaucauc agcgugaaca gcaucgacau cgaggugacc aaggagagcc      240

ccaucaccag caacagcacc aucaucaacc ccaccaacga gaccgacgac accgccggca      300

acaagcccaa cuaccagaga aagccccugg ugagcuucaa ggaggacccc acccccagcg      360

acaaccccuu cagcaagcug uacaaggaga ccaucgagac cuucgacaac aacgaggagg      420

agagcagcua cagcuacgag gagaucaacg accagaccaa cgacaacauc accgccagac      480

uggacagaau cgacgagaag cugagcgaga uccugggcau gcugcacacc cugguggugg      540

ccagcgccgg ccccaccagc gccagagacg gcaucagaga cgccaugauc ggccugagag      600

aggagaugau cgagaagauc agaaccgagg cccugaugac caacgacaga cuggaggcca      660

uggccagacu gagaaacgag gagagcgaga agauggccaa ggacaccagc gacgagguga      720

gccugaaccc caccagcgag aagcugaaca accugcugga gggcaacgac agcgacaacg      780

accugagccu ggaggacuuc ugaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10883
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10883
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaaguucg cccccgaauu ucacggcgag gacgcuaaca      120

auagagccac caaauuccug gaaagcauca aggggaaauu uacauccccu aaggauccga      180

aaaagaagga cucuauuauc agcgugaacu ccauugauau cgaggucacg aaagaaucuc      240

ccauuaccag caauuccaca aucaucaacc cuaccaauga gacagacgau accgcgggaa      300

acaagcccaa uuaccagcgg aaaccucucg uuucuuucaa ggaggacccc acaccuagcg      360

auaacccguu uuccaaacug uauaaggaaa ccauugagac guucgacaau aacgaagagg      420

agagcucuua cuccuaugaa gagaucaaug aucaaaccaa cgacaauauu acagcucgcc      480

uugauagaau cgacgaaaag cugagcgaga uucucggcau gcugcauacc cuuguggugg      540

ccucugccgg gcccacaucc gcucgggaug gaauccgcga cgccaugauu ggccugagag      600

aagagaugau cgagaaaauc cggaccgaag cucucaugac gaacgaccgc cuggaggcca      660

uggcgagacu gcggaaugaa gagagcgaaa agauggccaa agauacaucu gacgaggucu      720

cccucaaccc uaccagcgag aagcugaaca aucuucugga agggaacgau uccgacaaug      780

aucucucucu ggaggacuuu ugaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10884
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10884
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg caccagaauu ucacggagaa gacgcaaaca      120

acagagcaac aaaauucuua gaaucaauca aaggaaaauu cacaagccca aaagacccaa      180

aaaaaaaaga cucaauaaua agcguaaacu caauagacau agaaguaaca aaagaaagcc      240

caauaacaag caacagcaca auaauaaacc caacaaacga aacagaugac acagcuggaa      300

auaaaccaaa cuaccaaaga aaaccccuag ucagcuucaa agaagacccc acaccaucag      360

acaacccauu cagcaaacua uauaaagaaa caauagaaac auuugacaac aacgaagaag      420

aaucaucaua cucauacgaa gaaauaaacg accaaacaaa cgacaacaua accgcaagau      480

uagacagaau agaugaaaaa cuaucagaaa uacuaggaau gcuacacaca uuaguaguag      540

caagcgcagg accaacauca gcaagagacg gaauaagaga cgcaaugaua ggacucagag      600

aagaaaugau agaaaaaaua agaacagaag cacuaaugac aaacgacaga uuagaagcaa      660

uggcaagacu aagaaaugaa gaaucggaaa aaauggcaaa agacacauca gacgaaguaa      720

gccuaaaccc aacaucagaa aaauuaaaua accuacuaga aggaaacgac agcgacaacg      780

acuuaucacu agaagacuuc uaaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10885
<211>  1298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10885
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca      120

accgcgcgac aaaguuccua gaaucaauca agggcaaauu cacgagcccg aaagacccca      180

agaaaaagga cucaaucaua agcgugaacu cgaucgacau cgaggucacg aaagagagcc      240

cgaucacaag caacagcacc auaauaaacc cgaccaacga aacagacgac accgcgggca      300

acaaaccgaa cuaccaaaga aaaccgcucg ugagcuucaa agaagacccg accccaagcg      360

acaacccguu cucaaaacua uacaaggaaa cgaucgagac cuucgacaac aacgaggaag      420

agagcucgua cucguacgag gaaauaaacg accaaacaaa cgacaacaua accgcacgcc      480

uagacaggau cgacgaaaaa cucucggaaa uacucgggau gcuacacacg cucguggucg      540

cgagcgcagg cccgaccucg gccagggacg gcaucaggga cgcaaugaua ggccugcgag      600

aggaaaugau cgagaaaaua cgcaccgaag cacucaugac caacgacaga cucgaagcca      660

uggccaggcu caggaacgaa gaauccgaaa agauggcgaa agacaccucg gacgaggucu      720

cgcucaaccc cacgagcgag aaacugaaca accuacugga agggaacgac agcgacaacg      780

accuuucccu cgaggacuuc ugaggacuag ugaagggaac acccaaauuu aauucagccu      840

uaagcacaau uaauuaagag ugaaacguaa uuguacaagc aguuggucac ccaccauagg      900

gcaugaucaa caccgcaacc uuuccuuuuu cccccaguga uucugaaaaa ccccucuucc      960

cuucagcuug cuuagauguu ccaaauuuag uaagcuuaag gcggccuaca gaagaaaaag     1020

aaaaaaaagg ccacaaaagu ucccucucac uuucaguaaa uaaaauaaaa gcagcaacag     1080

aaauaaagaa auaaaugaaa uucaaaauga aauaaauauu guguugugca gcauuaaaaa     1140

aucaauaaaa auuaaaaaug agcaagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc     1260

cccccccccc aaaggcucuu uucagagcca ccagaauu                             1298


<210>  10886
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10886
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaguu ugcuccugaa uuccauggag aagaugcaaa caacagggcu      120

acuaaauucc uagaaucaau aaagggcaaa uucacaucac ccaaagaucc caagaaaaaa      180

gauaguauca uaucugucaa cucaauagau auagaaguaa ccaaagaaag cccuauaaca      240

ucaaauucaa cuauuaucaa cccaacaaau gagacagaug auacugcagg gaacaagccc      300

aauuaucaaa gaaaaccucu aguaaguuuc aaagaagacc cuacaccaag ugauaauccc      360

uuuucuaaac uauacaaaga aaccauagaa acauuugaua acaaugaaga agaauccagc      420

uauucauacg aagaaauaaa ugaucagaca aacgauaaua uaacagcaag auuagauagg      480

auugaugaaa aauuaaguga aauacuagga augcuucaca cauuaguagu ggcaagugca      540

ggaccuacau cugcucggga ugguauaaga gaugccauga uugguuuaag agaagaaaug      600

auagaaaaaa ucagaacuga agcauuaaug accaaugaca gauuagaagc uauggcaaga      660

cucaggaaug aggaaaguga aaagauggca aaagacacau cagaugaagu gucucucaau      720

ccaacaucag agaaauugaa caaccuauug gaagggaaug auagugacaa ugaucuauca      780

cuugaagauu ucugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10887
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10887
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcg      120

accaaguucc uggagagcau caaggggaag uucaccuccc cgaaggaccc caagaagaag      180

gacagcauca ucuccgugaa cagcaucgac aucgagguca cgaaggaguc ccccaucacc      240

agcaacucca ccaucaucaa ccccaccaac gagacggacg acaccgccgg caacaagccg      300

aacuaccagc ggaagccccu cgugagcuuc aaggaggacc ccacccccuc cgacaacccg      360

uucagcaagc uguacaagga gaccaucgag acguucgaca acaacgagga ggaguccagc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccuggaccgg      480

aucgacgaga agcucagcga gauccugggg augcugcaca cccucguggu cgccuccgcc      540

ggccccacga gcgcgcgcga cgggauccgg gacgccauga ucggccugcg cgaggagaug      600

aucgagaaga uccggaccga ggcccugaug accaacgacc gccucgaggc cauggcgcgg      660

cugcgcaacg aggaguccga gaagauggcc aaggacacca gcgacgaggu gucccugaac      720

cccacgagcg agaagcucaa caaccugcug gagggcaacg acagcgacaa cgaccucucc      780

cuggaggacu ucugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10888
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10888
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcc      120

accaaguucc ucgaguccau caagggcaag uucaccuccc ccaaggaccc caagaagaag      180

gacuccauca ucuccgucaa cuccaucgac aucgagguca ccaaggaguc ccccaucacc      240

uccaacucca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccagc gcaagccccu cgucuccuuc aaggaggacc ccacccccuc cgacaacccc      360

uucuccaagc ucuacaagga gaccaucgag accuucgaca acaacgagga ggaguccucc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccucgaccgc      480

aucgacgaga agcucuccga gauccucggc augcuccaca cccucgucgu cgccuccgcc      540

ggccccaccu ccgcccgcga cggcauccgc gacgccauga ucggccuccg cgaggagaug      600

aucgagaaga uccgcaccga ggcccucaug accaacgacc gccucgaggc cauggcccgc      660

cuccgcaacg aggaguccga gaagauggcc aaggacaccu ccgacgaggu cucccucaac      720

cccaccuccg agaagcucaa caaccuccuc gagggcaacg acuccgacaa cgaccucucc      780

cucgaggacu ucugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10889
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10889
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagca      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua uaucagugaa caguaucgau auugagguca cuaaagaaag cccaaucacg      240

uccaauucua ccauuaucaa ccccacaaau gagacugacg auaccgccgg aaacaagccu      300

aauuaccaga ggaaaccacu cguuucguuc aaggaggacc ccacaccuuc agauaaccca      360

uuuagcaaac uuuauaagga aaccauagag acuuucgaca auaacgaaga ggagaguucc      420

uacucuuaug aagagaucaa ugaucaaaca aacgacaaua uuaccgcgcg gcuggaucgc      480

aucgacgaaa aguugagcga gauuuuaggu augcugcaua cgcuaguggu agcuuccgcc      540

ggccccacuu cagcacgaga ugggauccgu gacgccauga uaggacucag agaagagaug      600

auugagaaaa ucaggaccga agcucugaug acaaacgacc ggcuugaggc aauggcccgc      660

cugagaaaug aagagaguga aaagauggcu aaagauacua gcgacgaggu gucuuugaac      720

ccuaccuccg agaagcucaa caaucugcug gaaggcaacg auucagacaa ugaucucagc      780

uuagaggacu uuugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10890
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10890
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caacagagcc      120

accaaguucc uggagagcau caagggcaag uucaccagcc ccaaggaccc caagaagaag      180

gacagcauca ucagcgugaa cagcaucgac aucgagguga ccaaggagag ccccaucacc      240

agcaacagca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccaga gaaagccccu ggugagcuuc aaggaggacc ccacccccag cgacaacccc      360

uucagcaagc uguacaagga gaccaucgag accuucgaca acaacgagga ggagagcagc      420

uacagcuacg aggagaucaa cgaccagacc aacgacaaca ucaccgccag acuggacaga      480

aucgacgaga agcugagcga gauccugggc augcugcaca cccugguggu ggccagcgcc      540

ggccccacca gcgccagaga cggcaucaga gacgccauga ucggccugag agaggagaug      600

aucgagaaga ucagaaccga ggcccugaug accaacgaca gacuggaggc cauggccaga      660

cugagaaacg aggagagcga gaagauggcc aaggacacca gcgacgaggu gagccugaac      720

cccaccagcg agaagcugaa caaccugcug gagggcaacg acagcgacaa cgaccugagc      780

cuggaggacu ucugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10891
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10891
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagcc      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua ucagcgugaa cuccauugau aucgagguca cgaaagaauc ucccauuacc      240

agcaauucca caaucaucaa cccuaccaau gagacagacg auaccgcggg aaacaagccc      300

aauuaccagc ggaaaccucu cguuucuuuc aaggaggacc ccacaccuag cgauaacccg      360

uuuuccaaac uguauaagga aaccauugag acguucgaca auaacgaaga ggagagcucu      420

uacuccuaug aagagaucaa ugaucaaacc aacgacaaua uuacagcucg ccuugauaga      480

aucgacgaaa agcugagcga gauucucggc augcugcaua cccuuguggu ggccucugcc      540

gggcccacau ccgcucggga uggaauccgc gacgccauga uuggccugag agaagagaug      600

aucgagaaaa uccggaccga agcucucaug acgaacgacc gccuggaggc cauggcgaga      660

cugcggaaug aagagagcga aaagauggcc aaagauacau cugacgaggu cucccucaac      720

ccuaccagcg agaagcugaa caaucuucug gaagggaacg auuccgacaa ugaucucucu      780

cuggaggacu uuugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10892
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10892
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcaccagaa uuucacggag aagacgcaaa caacagagca      120

acaaaauucu uagaaucaau caaaggaaaa uucacaagcc caaaagaccc aaaaaaaaaa      180

gacucaauaa uaagcguaaa cucaauagac auagaaguaa caaaagaaag cccaauaaca      240

agcaacagca caauaauaaa cccaacaaac gaaacagaug acacagcugg aaauaaacca      300

aacuaccaaa gaaaaccccu agucagcuuc aaagaagacc ccacaccauc agacaaccca      360

uucagcaaac uauauaaaga aacaauagaa acauuugaca acaacgaaga agaaucauca      420

uacucauacg aagaaauaaa cgaccaaaca aacgacaaca uaaccgcaag auuagacaga      480

auagaugaaa aacuaucaga aauacuagga augcuacaca cauuaguagu agcaagcgca      540

ggaccaacau cagcaagaga cggaauaaga gacgcaauga uaggacucag agaagaaaug      600

auagaaaaaa uaagaacaga agcacuaaug acaaacgaca gauuagaagc aauggcaaga      660

cuaagaaaug aagaaucgga aaaaauggca aaagacacau cagacgaagu aagccuaaac      720

ccaacaucag aaaaauuaaa uaaccuacua gaaggaaacg acagcgacaa cgacuuauca      780

cuagaagacu ucuaaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10893
<211>  1074
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design f-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10893
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcgcccgag uuccacggcg aggacgcgaa caaccgcgcg      120

acaaaguucc uagaaucaau caagggcaaa uucacgagcc cgaaagaccc caagaaaaag      180

gacucaauca uaagcgugaa cucgaucgac aucgagguca cgaaagagag cccgaucaca      240

agcaacagca ccauaauaaa cccgaccaac gaaacagacg acaccgcggg caacaaaccg      300

aacuaccaaa gaaaaccgcu cgugagcuuc aaagaagacc cgaccccaag cgacaacccg      360

uucucaaaac uauacaagga aacgaucgag accuucgaca acaacgagga agagagcucg      420

uacucguacg aggaaauaaa cgaccaaaca aacgacaaca uaaccgcacg ccuagacagg      480

aucgacgaaa aacucucgga aauacucggg augcuacaca cgcucguggu cgcgagcgca      540

ggcccgaccu cggccaggga cggcaucagg gacgcaauga uaggccugcg agaggaaaug      600

aucgagaaaa uacgcaccga agcacucaug accaacgaca gacucgaagc cauggccagg      660

cucaggaacg aagaauccga aaagauggcg aaagacaccu cggacgaggu cucgcucaac      720

cccacgagcg agaaacugaa caaccuacug gaagggaacg acagcgacaa cgaccuuucc      780

cucgaggacu ucugaggacu aguacuggcu gcaucucccu uuccucuguc cuccauccuu      840

cucccaggau ggugaagggg gaccugguac ccagugaucc ccaccccagg auccuaaauc      900

augacuuacc ugcuaauaaa aacucauugg aaaagugaga agaucuaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1020

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1074


<210>  10894
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10894
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaguu ugcuccugaa uuccauggag aagaugcaaa caacagggcu      120

acuaaauucc uagaaucaau aaagggcaaa uucacaucac ccaaagaucc caagaaaaaa      180

gauaguauca uaucugucaa cucaauagau auagaaguaa ccaaagaaag cccuauaaca      240

ucaaauucaa cuauuaucaa cccaacaaau gagacagaug auacugcagg gaacaagccc      300

aauuaucaaa gaaaaccucu aguaaguuuc aaagaagacc cuacaccaag ugauaauccc      360

uuuucuaaac uauacaaaga aaccauagaa acauuugaua acaaugaaga agaauccagc      420

uauucauacg aagaaauaaa ugaucagaca aacgauaaua uaacagcaag auuagauagg      480

auugaugaaa aauuaaguga aauacuagga augcuucaca cauuaguagu ggcaagugca      540

ggaccuacau cugcucggga ugguauaaga gaugccauga uugguuuaag agaagaaaug      600

auagaaaaaa ucagaacuga agcauuaaug accaaugaca gauuagaagc uauggcaaga      660

cucaggaaug aggaaaguga aaagauggca aaagacacau cagaugaagu gucucucaau      720

ccaacaucag agaaauugaa caaccuauug gaagggaaug auagugacaa ugaucuauca      780

cuugaagauu ucugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10895
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10895
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcg      120

accaaguucc uggagagcau caaggggaag uucaccuccc cgaaggaccc caagaagaag      180

gacagcauca ucuccgugaa cagcaucgac aucgagguca cgaaggaguc ccccaucacc      240

agcaacucca ccaucaucaa ccccaccaac gagacggacg acaccgccgg caacaagccg      300

aacuaccagc ggaagccccu cgugagcuuc aaggaggacc ccacccccuc cgacaacccg      360

uucagcaagc uguacaagga gaccaucgag acguucgaca acaacgagga ggaguccagc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccuggaccgg      480

aucgacgaga agcucagcga gauccugggg augcugcaca cccucguggu cgccuccgcc      540

ggccccacga gcgcgcgcga cgggauccgg gacgccauga ucggccugcg cgaggagaug      600

aucgagaaga uccggaccga ggcccugaug accaacgacc gccucgaggc cauggcgcgg      660

cugcgcaacg aggaguccga gaagauggcc aaggacacca gcgacgaggu gucccugaac      720

cccacgagcg agaagcucaa caaccugcug gagggcaacg acagcgacaa cgaccucucc      780

cuggaggacu ucugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10896
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10896
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caaccgcgcc      120

accaaguucc ucgaguccau caagggcaag uucaccuccc ccaaggaccc caagaagaag      180

gacuccauca ucuccgucaa cuccaucgac aucgagguca ccaaggaguc ccccaucacc      240

uccaacucca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccagc gcaagccccu cgucuccuuc aaggaggacc ccacccccuc cgacaacccc      360

uucuccaagc ucuacaagga gaccaucgag accuucgaca acaacgagga ggaguccucc      420

uacuccuacg aggagaucaa cgaccagacc aacgacaaca ucaccgcccg ccucgaccgc      480

aucgacgaga agcucuccga gauccucggc augcuccaca cccucgucgu cgccuccgcc      540

ggccccaccu ccgcccgcga cggcauccgc gacgccauga ucggccuccg cgaggagaug      600

aucgagaaga uccgcaccga ggcccucaug accaacgacc gccucgaggc cauggcccgc      660

cuccgcaacg aggaguccga gaagauggcc aaggacaccu ccgacgaggu cucccucaac      720

cccaccuccg agaagcucaa caaccuccuc gagggcaacg acuccgacaa cgaccucucc      780

cucgaggacu ucugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10897
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10897
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagca      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua uaucagugaa caguaucgau auugagguca cuaaagaaag cccaaucacg      240

uccaauucua ccauuaucaa ccccacaaau gagacugacg auaccgccgg aaacaagccu      300

aauuaccaga ggaaaccacu cguuucguuc aaggaggacc ccacaccuuc agauaaccca      360

uuuagcaaac uuuauaagga aaccauagag acuuucgaca auaacgaaga ggagaguucc      420

uacucuuaug aagagaucaa ugaucaaaca aacgacaaua uuaccgcgcg gcuggaucgc      480

aucgacgaaa aguugagcga gauuuuaggu augcugcaua cgcuaguggu agcuuccgcc      540

ggccccacuu cagcacgaga ugggauccgu gacgccauga uaggacucag agaagagaug      600

auugagaaaa ucaggaccga agcucugaug acaaacgacc ggcuugaggc aauggcccgc      660

cugagaaaug aagagaguga aaagauggcu aaagauacua gcgacgaggu gucuuugaac      720

ccuaccuccg agaagcucaa caaucugcug gaaggcaacg auucagacaa ugaucucagc      780

uuagaggacu uuugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10898
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10898
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgag uuccacggcg aggacgccaa caacagagcc      120

accaaguucc uggagagcau caagggcaag uucaccagcc ccaaggaccc caagaagaag      180

gacagcauca ucagcgugaa cagcaucgac aucgagguga ccaaggagag ccccaucacc      240

agcaacagca ccaucaucaa ccccaccaac gagaccgacg acaccgccgg caacaagccc      300

aacuaccaga gaaagccccu ggugagcuuc aaggaggacc ccacccccag cgacaacccc      360

uucagcaagc uguacaagga gaccaucgag accuucgaca acaacgagga ggagagcagc      420

uacagcuacg aggagaucaa cgaccagacc aacgacaaca ucaccgccag acuggacaga      480

aucgacgaga agcugagcga gauccugggc augcugcaca cccugguggu ggccagcgcc      540

ggccccacca gcgccagaga cggcaucaga gacgccauga ucggccugag agaggagaug      600

aucgagaaga ucagaaccga ggcccugaug accaacgaca gacuggaggc cauggccaga      660

cugagaaacg aggagagcga gaagauggcc aaggacacca gcgacgaggu gagccugaac      720

cccaccagcg agaagcugaa caaccugcug gagggcaacg acagcgacaa cgaccugagc      780

cuggaggacu ucugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10899
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10899
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggagaaguu cgcccccgaa uuucacggcg aggacgcuaa caauagagcc      120

accaaauucc uggaaagcau caaggggaaa uuuacauccc cuaaggaucc gaaaaagaag      180

gacucuauua ucagcgugaa cuccauugau aucgagguca cgaaagaauc ucccauuacc      240

agcaauucca caaucaucaa cccuaccaau gagacagacg auaccgcggg aaacaagccc      300

aauuaccagc ggaaaccucu cguuucuuuc aaggaggacc ccacaccuag cgauaacccg      360

uuuuccaaac uguauaagga aaccauugag acguucgaca auaacgaaga ggagagcucu      420

uacuccuaug aagagaucaa ugaucaaacc aacgacaaua uuacagcucg ccuugauaga      480

aucgacgaaa agcugagcga gauucucggc augcugcaua cccuuguggu ggccucugcc      540

gggcccacau ccgcucggga uggaauccgc gacgccauga uuggccugag agaagagaug      600

aucgagaaaa uccggaccga agcucucaug acgaacgacc gccuggaggc cauggcgaga      660

cugcggaaug aagagagcga aaagauggcc aaagauacau cugacgaggu cucccucaac      720

ccuaccagcg agaagcugaa caaucuucug gaagggaacg auuccgacaa ugaucucucu      780

cuggaggacu uuugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10900
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10900
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcaccagaa uuucacggag aagacgcaaa caacagagca      120

acaaaauucu uagaaucaau caaaggaaaa uucacaagcc caaaagaccc aaaaaaaaaa      180

gacucaauaa uaagcguaaa cucaauagac auagaaguaa caaaagaaag cccaauaaca      240

agcaacagca caauaauaaa cccaacaaac gaaacagaug acacagcugg aaauaaacca      300

aacuaccaaa gaaaaccccu agucagcuuc aaagaagacc ccacaccauc agacaaccca      360

uucagcaaac uauauaaaga aacaauagaa acauuugaca acaacgaaga agaaucauca      420

uacucauacg aagaaauaaa cgaccaaaca aacgacaaca uaaccgcaag auuagacaga      480

auagaugaaa aacuaucaga aauacuagga augcuacaca cauuaguagu agcaagcgca      540

ggaccaacau cagcaagaga cggaauaaga gacgcaauga uaggacucag agaagaaaug      600

auagaaaaaa uaagaacaga agcacuaaug acaaacgaca gauuagaagc aauggcaaga      660

cuaagaaaug aagaaucgga aaaaauggca aaagacacau cagacgaagu aagccuaaac      720

ccaacaucag aaaaauuaaa uaaccuacua gaaggaaacg acagcgacaa cgacuuauca      780

cuagaagacu ucuaaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10901
<211>  1070
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10901
gggagacuuu cccauucugu agcagaauuu gguguugccu guggucuugg ucccgcggag       60

aagcuuacca uggaaaaauu cgcgcccgag uuccacggcg aggacgcgaa caaccgcgcg      120

acaaaguucc uagaaucaau caagggcaaa uucacgagcc cgaaagaccc caagaaaaag      180

gacucaauca uaagcgugaa cucgaucgac aucgagguca cgaaagagag cccgaucaca      240

agcaacagca ccauaauaaa cccgaccaac gaaacagacg acaccgcggg caacaaaccg      300

aacuaccaaa gaaaaccgcu cgugagcuuc aaagaagacc cgaccccaag cgacaacccg      360

uucucaaaac uauacaagga aacgaucgag accuucgaca acaacgagga agagagcucg      420

uacucguacg aggaaauaaa cgaccaaaca aacgacaaca uaaccgcacg ccuagacagg      480

aucgacgaaa aacucucgga aauacucggg augcuacaca cgcucguggu cgcgagcgca      540

ggcccgaccu cggccaggga cggcaucagg gacgcaauga uaggccugcg agaggaaaug      600

aucgagaaaa uacgcaccga agcacucaug accaacgaca gacucgaagc cauggccagg      660

cucaggaacg aagaauccga aaagauggcg aaagacaccu cggacgaggu cucgcucaac      720

cccacgagcg agaaacugaa caaccuacug gaagggaacg acagcgacaa cgaccuuucc      780

cucgaggacu ucugaggacu aguggaagca uuuuccuggc ugauuaaaag aaauuacuca      840

gcuaugguca ucuguuccug uuagaaggcu augcagcaua uuauauacua ugcgcauguu      900

augaaaugca uaauaaaaaa uuuuaaaaaa ucuaaaagau cuaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     1020

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                1070


<210>  10902
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10902
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaguuugc uccugaauuc      120

cauggagaag augcaaacaa cagggcuacu aaauuccuag aaucaauaaa gggcaaauuc      180

acaucaccca aagaucccaa gaaaaaagau aguaucauau cugucaacuc aauagauaua      240

gaaguaacca aagaaagccc uauaacauca aauucaacua uuaucaaccc aacaaaugag      300

acagaugaua cugcagggaa caagcccaau uaucaaagaa aaccucuagu aaguuucaaa      360

gaagacccua caccaaguga uaaucccuuu ucuaaacuau acaaagaaac cauagaaaca      420

uuugauaaca augaagaaga auccagcuau ucauacgaag aaauaaauga ucagacaaac      480

gauaauauaa cagcaagauu agauaggauu gaugaaaaau uaagugaaau acuaggaaug      540

cuucacacau uaguaguggc aagugcagga ccuacaucug cucgggaugg uauaagagau      600

gccaugauug guuuaagaga agaaaugaua gaaaaaauca gaacugaagc auuaaugacc      660

aaugacagau uagaagcuau ggcaagacuc aggaaugagg aaagugaaaa gauggcaaaa      720

gacacaucag augaaguguc ucucaaucca acaucagaga aauugaacaa ccuauuggaa      780

gggaaugaua gugacaauga ucuaucacuu gaagauuucu gaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10903
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10903
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgcgacc aaguuccugg agagcaucaa ggggaaguuc      180

accuccccga aggaccccaa gaagaaggac agcaucaucu ccgugaacag caucgacauc      240

gaggucacga aggagucccc caucaccagc aacuccacca ucaucaaccc caccaacgag      300

acggacgaca ccgccggcaa caagccgaac uaccagcgga agccccucgu gagcuucaag      360

gaggacccca cccccuccga caacccguuc agcaagcugu acaaggagac caucgagacg      420

uucgacaaca acgaggagga guccagcuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu ggaccggauc gacgagaagc ucagcgagau ccuggggaug      540

cugcacaccc ucguggucgc cuccgccggc cccacgagcg cgcgcgacgg gauccgggac      600

gccaugaucg gccugcgcga ggagaugauc gagaagaucc ggaccgaggc ccugaugacc      660

aacgaccgcc ucgaggccau ggcgcggcug cgcaacgagg aguccgagaa gauggccaag      720

gacaccagcg acgagguguc ccugaacccc acgagcgaga agcucaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccucucccug gaggacuucu gaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10904
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10904
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgccacc aaguuccucg aguccaucaa gggcaaguuc      180

accuccccca aggaccccaa gaagaaggac uccaucaucu ccgucaacuc caucgacauc      240

gaggucacca aggagucccc caucaccucc aacuccacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagcgca agccccucgu cuccuucaag      360

gaggacccca cccccuccga caaccccuuc uccaagcucu acaaggagac caucgagacc      420

uucgacaaca acgaggagga guccuccuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu cgaccgcauc gacgagaagc ucuccgagau ccucggcaug      540

cuccacaccc ucgucgucgc cuccgccggc cccaccuccg cccgcgacgg cauccgcgac      600

gccaugaucg gccuccgcga ggagaugauc gagaagaucc gcaccgaggc ccucaugacc      660

aacgaccgcc ucgaggccau ggcccgccuc cgcaacgagg aguccgagaa gauggccaag      720

gacaccuccg acgaggucuc ccucaacccc accuccgaga agcucaacaa ccuccucgag      780

ggcaacgacu ccgacaacga ccucucccuc gaggacuucu gaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10905
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10905
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagcaacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauau cagugaacag uaucgauauu      240

gaggucacua aagaaagccc aaucacgucc aauucuacca uuaucaaccc cacaaaugag      300

acugacgaua ccgccggaaa caagccuaau uaccagagga aaccacucgu uucguucaag      360

gaggacccca caccuucaga uaacccauuu agcaaacuuu auaaggaaac cauagagacu      420

uucgacaaua acgaagagga gaguuccuac ucuuaugaag agaucaauga ucaaacaaac      480

gacaauauua ccgcgcggcu ggaucgcauc gacgaaaagu ugagcgagau uuuagguaug      540

cugcauacgc uagugguagc uuccgccggc cccacuucag cacgagaugg gauccgugac      600

gccaugauag gacucagaga agagaugauu gagaaaauca ggaccgaagc ucugaugaca      660

aacgaccggc uugaggcaau ggcccgccug agaaaugaag agagugaaaa gauggcuaaa      720

gauacuagcg acgagguguc uuugaacccu accuccgaga agcucaacaa ucugcuggaa      780

ggcaacgauu cagacaauga ucucagcuua gaggacuuuu gaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10906
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10906
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa cagagccacc aaguuccugg agagcaucaa gggcaaguuc      180

accagcccca aggaccccaa gaagaaggac agcaucauca gcgugaacag caucgacauc      240

gaggugacca aggagagccc caucaccagc aacagcacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagagaa agccccuggu gagcuucaag      360

gaggacccca cccccagcga caaccccuuc agcaagcugu acaaggagac caucgagacc      420

uucgacaaca acgaggagga gagcagcuac agcuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgccagacu ggacagaauc gacgagaagc ugagcgagau ccugggcaug      540

cugcacaccc uggugguggc cagcgccggc cccaccagcg ccagagacgg caucagagac      600

gccaugaucg gccugagaga ggagaugauc gagaagauca gaaccgaggc ccugaugacc      660

aacgacagac uggaggccau ggccagacug agaaacgagg agagcgagaa gauggccaag      720

gacaccagcg acgaggugag ccugaacccc accagcgaga agcugaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccugagccug gaggacuucu gaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10907
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10907
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagccacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauca gcgugaacuc cauugauauc      240

gaggucacga aagaaucucc cauuaccagc aauuccacaa ucaucaaccc uaccaaugag      300

acagacgaua ccgcgggaaa caagcccaau uaccagcgga aaccucucgu uucuuucaag      360

gaggacccca caccuagcga uaacccguuu uccaaacugu auaaggaaac cauugagacg      420

uucgacaaua acgaagagga gagcucuuac uccuaugaag agaucaauga ucaaaccaac      480

gacaauauua cagcucgccu ugauagaauc gacgaaaagc ugagcgagau ucucggcaug      540

cugcauaccc uugugguggc cucugccggg cccacauccg cucgggaugg aauccgcgac      600

gccaugauug gccugagaga agagaugauc gagaaaaucc ggaccgaagc ucucaugacg      660

aacgaccgcc uggaggccau ggcgagacug cggaaugaag agagcgaaaa gauggccaaa      720

gauacaucug acgaggucuc ccucaacccu accagcgaga agcugaacaa ucuucuggaa      780

gggaacgauu ccgacaauga ucucucucug gaggacuuuu gaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10908
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10908
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc accagaauuu      120

cacggagaag acgcaaacaa cagagcaaca aaauucuuag aaucaaucaa aggaaaauuc      180

acaagcccaa aagacccaaa aaaaaaagac ucaauaauaa gcguaaacuc aauagacaua      240

gaaguaacaa aagaaagccc aauaacaagc aacagcacaa uaauaaaccc aacaaacgaa      300

acagaugaca cagcuggaaa uaaaccaaac uaccaaagaa aaccccuagu cagcuucaaa      360

gaagacccca caccaucaga caacccauuc agcaaacuau auaaagaaac aauagaaaca      420

uuugacaaca acgaagaaga aucaucauac ucauacgaag aaauaaacga ccaaacaaac      480

gacaacauaa ccgcaagauu agacagaaua gaugaaaaac uaucagaaau acuaggaaug      540

cuacacacau uaguaguagc aagcgcagga ccaacaucag caagagacgg aauaagagac      600

gcaaugauag gacucagaga agaaaugaua gaaaaaauaa gaacagaagc acuaaugaca      660

aacgacagau uagaagcaau ggcaagacua agaaaugaag aaucggaaaa aauggcaaaa      720

gacacaucag acgaaguaag ccuaaaccca acaucagaaa aauuaaauaa ccuacuagaa      780

ggaaacgaca gcgacaacga cuuaucacua gaagacuucu aaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10909
<211>  1085
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10909
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc gcccgaguuc      120

cacggcgagg acgcgaacaa ccgcgcgaca aaguuccuag aaucaaucaa gggcaaauuc      180

acgagcccga aagaccccaa gaaaaaggac ucaaucauaa gcgugaacuc gaucgacauc      240

gaggucacga aagagagccc gaucacaagc aacagcacca uaauaaaccc gaccaacgaa      300

acagacgaca ccgcgggcaa caaaccgaac uaccaaagaa aaccgcucgu gagcuucaaa      360

gaagacccga ccccaagcga caacccguuc ucaaaacuau acaaggaaac gaucgagacc      420

uucgacaaca acgaggaaga gagcucguac ucguacgagg aaauaaacga ccaaacaaac      480

gacaacauaa ccgcacgccu agacaggauc gacgaaaaac ucucggaaau acucgggaug      540

cuacacacgc ucguggucgc gagcgcaggc ccgaccucgg ccagggacgg caucagggac      600

gcaaugauag gccugcgaga ggaaaugauc gagaaaauac gcaccgaagc acucaugacc      660

aacgacagac ucgaagccau ggccaggcuc aggaacgaag aauccgaaaa gauggcgaaa      720

gacaccucgg acgaggucuc gcucaacccc acgagcgaga aacugaacaa ccuacuggaa      780

gggaacgaca gcgacaacga ccuuucccuc gaggacuucu gaggacuagu aauaaggaaa      840

cuguaugaau gucugugggc aggaagugaa gagauccuuc uguaaagguu uuuggaauua      900

ugucugcuga auaauaaacu uuuuugaaau aauaaaucug guagaaaaau gagaucuaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca     1080

gaauu                                                                 1085


<210>  10910
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10910
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaguuugc uccugaauuc      120

cauggagaag augcaaacaa cagggcuacu aaauuccuag aaucaauaaa gggcaaauuc      180

acaucaccca aagaucccaa gaaaaaagau aguaucauau cugucaacuc aauagauaua      240

gaaguaacca aagaaagccc uauaacauca aauucaacua uuaucaaccc aacaaaugag      300

acagaugaua cugcagggaa caagcccaau uaucaaagaa aaccucuagu aaguuucaaa      360

gaagacccua caccaaguga uaaucccuuu ucuaaacuau acaaagaaac cauagaaaca      420

uuugauaaca augaagaaga auccagcuau ucauacgaag aaauaaauga ucagacaaac      480

gauaauauaa cagcaagauu agauaggauu gaugaaaaau uaagugaaau acuaggaaug      540

cuucacacau uaguaguggc aagugcagga ccuacaucug cucgggaugg uauaagagau      600

gccaugauug guuuaagaga agaaaugaua gaaaaaauca gaacugaagc auuaaugacc      660

aaugacagau uagaagcuau ggcaagacuc aggaaugagg aaagugaaaa gauggcaaaa      720

gacacaucag augaaguguc ucucaaucca acaucagaga aauugaacaa ccuauuggaa      780

gggaaugaua gugacaauga ucuaucacuu gaagauuucu gaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10911
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10911
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgcgacc aaguuccugg agagcaucaa ggggaaguuc      180

accuccccga aggaccccaa gaagaaggac agcaucaucu ccgugaacag caucgacauc      240

gaggucacga aggagucccc caucaccagc aacuccacca ucaucaaccc caccaacgag      300

acggacgaca ccgccggcaa caagccgaac uaccagcgga agccccucgu gagcuucaag      360

gaggacccca cccccuccga caacccguuc agcaagcugu acaaggagac caucgagacg      420

uucgacaaca acgaggagga guccagcuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu ggaccggauc gacgagaagc ucagcgagau ccuggggaug      540

cugcacaccc ucguggucgc cuccgccggc cccacgagcg cgcgcgacgg gauccgggac      600

gccaugaucg gccugcgcga ggagaugauc gagaagaucc ggaccgaggc ccugaugacc      660

aacgaccgcc ucgaggccau ggcgcggcug cgcaacgagg aguccgagaa gauggccaag      720

gacaccagcg acgagguguc ccugaacccc acgagcgaga agcucaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccucucccug gaggacuucu gaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10912
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10912
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa ccgcgccacc aaguuccucg aguccaucaa gggcaaguuc      180

accuccccca aggaccccaa gaagaaggac uccaucaucu ccgucaacuc caucgacauc      240

gaggucacca aggagucccc caucaccucc aacuccacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagcgca agccccucgu cuccuucaag      360

gaggacccca cccccuccga caaccccuuc uccaagcucu acaaggagac caucgagacc      420

uucgacaaca acgaggagga guccuccuac uccuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgcccgccu cgaccgcauc gacgagaagc ucuccgagau ccucggcaug      540

cuccacaccc ucgucgucgc cuccgccggc cccaccuccg cccgcgacgg cauccgcgac      600

gccaugaucg gccuccgcga ggagaugauc gagaagaucc gcaccgaggc ccucaugacc      660

aacgaccgcc ucgaggccau ggcccgccuc cgcaacgagg aguccgagaa gauggccaag      720

gacaccuccg acgaggucuc ccucaacccc accuccgaga agcucaacaa ccuccucgag      780

ggcaacgacu ccgacaacga ccucucccuc gaggacuucu gaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10913
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10913
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagcaacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauau cagugaacag uaucgauauu      240

gaggucacua aagaaagccc aaucacgucc aauucuacca uuaucaaccc cacaaaugag      300

acugacgaua ccgccggaaa caagccuaau uaccagagga aaccacucgu uucguucaag      360

gaggacccca caccuucaga uaacccauuu agcaaacuuu auaaggaaac cauagagacu      420

uucgacaaua acgaagagga gaguuccuac ucuuaugaag agaucaauga ucaaacaaac      480

gacaauauua ccgcgcggcu ggaucgcauc gacgaaaagu ugagcgagau uuuagguaug      540

cugcauacgc uagugguagc uuccgccggc cccacuucag cacgagaugg gauccgugac      600

gccaugauag gacucagaga agagaugauu gagaaaauca ggaccgaagc ucugaugaca      660

aacgaccggc uugaggcaau ggcccgccug agaaaugaag agagugaaaa gauggcuaaa      720

gauacuagcg acgagguguc uuugaacccu accuccgaga agcucaacaa ucugcuggaa      780

ggcaacgauu cagacaauga ucucagcuua gaggacuuuu gaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10914
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10914
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaguuc      120

cacggcgagg acgccaacaa cagagccacc aaguuccugg agagcaucaa gggcaaguuc      180

accagcccca aggaccccaa gaagaaggac agcaucauca gcgugaacag caucgacauc      240

gaggugacca aggagagccc caucaccagc aacagcacca ucaucaaccc caccaacgag      300

accgacgaca ccgccggcaa caagcccaac uaccagagaa agccccuggu gagcuucaag      360

gaggacccca cccccagcga caaccccuuc agcaagcugu acaaggagac caucgagacc      420

uucgacaaca acgaggagga gagcagcuac agcuacgagg agaucaacga ccagaccaac      480

gacaacauca ccgccagacu ggacagaauc gacgagaagc ugagcgagau ccugggcaug      540

cugcacaccc uggugguggc cagcgccggc cccaccagcg ccagagacgg caucagagac      600

gccaugaucg gccugagaga ggagaugauc gagaagauca gaaccgaggc ccugaugacc      660

aacgacagac uggaggccau ggccagacug agaaacgagg agagcgagaa gauggccaag      720

gacaccagcg acgaggugag ccugaacccc accagcgaga agcugaacaa ccugcuggag      780

ggcaacgaca gcgacaacga ccugagccug gaggacuucu gaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10915
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10915
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg agaaguucgc ccccgaauuu      120

cacggcgagg acgcuaacaa uagagccacc aaauuccugg aaagcaucaa ggggaaauuu      180

acauccccua aggauccgaa aaagaaggac ucuauuauca gcgugaacuc cauugauauc      240

gaggucacga aagaaucucc cauuaccagc aauuccacaa ucaucaaccc uaccaaugag      300

acagacgaua ccgcgggaaa caagcccaau uaccagcgga aaccucucgu uucuuucaag      360

gaggacccca caccuagcga uaacccguuu uccaaacugu auaaggaaac cauugagacg      420

uucgacaaua acgaagagga gagcucuuac uccuaugaag agaucaauga ucaaaccaac      480

gacaauauua cagcucgccu ugauagaauc gacgaaaagc ugagcgagau ucucggcaug      540

cugcauaccc uugugguggc cucugccggg cccacauccg cucgggaugg aauccgcgac      600

gccaugauug gccugagaga agagaugauc gagaaaaucc ggaccgaagc ucucaugacg      660

aacgaccgcc uggaggccau ggcgagacug cggaaugaag agagcgaaaa gauggccaaa      720

gauacaucug acgaggucuc ccucaacccu accagcgaga agcugaacaa ucuucuggaa      780

gggaacgauu ccgacaauga ucucucucug gaggacuuuu gaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10916
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10916
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc accagaauuu      120

cacggagaag acgcaaacaa cagagcaaca aaauucuuag aaucaaucaa aggaaaauuc      180

acaagcccaa aagacccaaa aaaaaaagac ucaauaauaa gcguaaacuc aauagacaua      240

gaaguaacaa aagaaagccc aauaacaagc aacagcacaa uaauaaaccc aacaaacgaa      300

acagaugaca cagcuggaaa uaaaccaaac uaccaaagaa aaccccuagu cagcuucaaa      360

gaagacccca caccaucaga caacccauuc agcaaacuau auaaagaaac aauagaaaca      420

uuugacaaca acgaagaaga aucaucauac ucauacgaag aaauaaacga ccaaacaaac      480

gacaacauaa ccgcaagauu agacagaaua gaugaaaaac uaucagaaau acuaggaaug      540

cuacacacau uaguaguagc aagcgcagga ccaacaucag caagagacgg aauaagagac      600

gcaaugauag gacucagaga agaaaugaua gaaaaaauaa gaacagaagc acuaaugaca      660

aacgacagau uagaagcaau ggcaagacua agaaaugaag aaucggaaaa aauggcaaaa      720

gacacaucag acgaaguaag ccuaaaccca acaucagaaa aauuaaauaa ccuacuagaa      780

ggaaacgaca gcgacaacga cuuaucacua gaagacuucu aaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10917
<211>  1317
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10917
gggagagucc gcucagccag guugcagaag cggcuuagcg uguguccuaa ucuucucucu       60

gcguguaggu aggccugugc cgcaaacaag cuuaccaugg aaaaauucgc gcccgaguuc      120

cacggcgagg acgcgaacaa ccgcgcgaca aaguuccuag aaucaaucaa gggcaaauuc      180

acgagcccga aagaccccaa gaaaaaggac ucaaucauaa gcgugaacuc gaucgacauc      240

gaggucacga aagagagccc gaucacaagc aacagcacca uaauaaaccc gaccaacgaa      300

acagacgaca ccgcgggcaa caaaccgaac uaccaaagaa aaccgcucgu gagcuucaaa      360

gaagacccga ccccaagcga caacccguuc ucaaaacuau acaaggaaac gaucgagacc      420

uucgacaaca acgaggaaga gagcucguac ucguacgagg aaauaaacga ccaaacaaac      480

gacaacauaa ccgcacgccu agacaggauc gacgaaaaac ucucggaaau acucgggaug      540

cuacacacgc ucguggucgc gagcgcaggc ccgaccucgg ccagggacgg caucagggac      600

gcaaugauag gccugcgaga ggaaaugauc gagaaaauac gcaccgaagc acucaugacc      660

aacgacagac ucgaagccau ggccaggcuc aggaacgaag aauccgaaaa gauggcgaaa      720

gacaccucgg acgaggucuc gcucaacccc acgagcgaga aacugaacaa ccuacuggaa      780

gggaacgaca gcgacaacga ccuuucccuc gaggacuucu gaggacuagu gaagggaaca      840

cccaaauuua auucagccuu aagcacaauu aauuaagagu gaaacguaau uguacaagca      900

guuggucacc caccauaggg caugaucaac accgcaaccu uuccuuuuuc ccccagugau      960

ucugaaaaac cccucuuccc uucagcuugc uuagauguuc caaauuuagu aagcuuaagg     1020

cggccuacag aagaaaaaga aaaaaaaggc cacaaaaguu cccucucacu uucaguaaau     1080

aaaauaaaag cagcaacaga aauaaagaaa uaaaugaaau ucaaaaugaa auaaauauug     1140

uguugugcag cauuaaaaaa ucaauaaaaa uuaaaaauga gcaagaucua aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1260

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1317


<210>  10918
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10918
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aguuugcucc ugaauuccau ggagaagaug caaacaacag ggcuacuaaa      180

uuccuagaau caauaaaggg caaauucaca ucacccaaag aucccaagaa aaaagauagu      240

aucauaucug ucaacucaau agauauagaa guaaccaaag aaagcccuau aacaucaaau      300

ucaacuauua ucaacccaac aaaugagaca gaugauacug cagggaacaa gcccaauuau      360

caaagaaaac cucuaguaag uuucaaagaa gacccuacac caagugauaa ucccuuuucu      420

aaacuauaca aagaaaccau agaaacauuu gauaacaaug aagaagaauc cagcuauuca      480

uacgaagaaa uaaaugauca gacaaacgau aauauaacag caagauuaga uaggauugau      540

gaaaaauuaa gugaaauacu aggaaugcuu cacacauuag uaguggcaag ugcaggaccu      600

acaucugcuc gggaugguau aagagaugcc augauugguu uaagagaaga aaugauagaa      660

aaaaucagaa cugaagcauu aaugaccaau gacagauuag aagcuauggc aagacucagg      720

aaugaggaaa gugaaaagau ggcaaaagac acaucagaug aagugucucu caauccaaca      780

ucagagaaau ugaacaaccu auuggaaggg aaugauagug acaaugaucu aucacuugaa      840

gauuucugag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10919
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10919
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgcgaccaag      180

uuccuggaga gcaucaaggg gaaguucacc uccccgaagg accccaagaa gaaggacagc      240

aucaucuccg ugaacagcau cgacaucgag gucacgaagg agucccccau caccagcaac      300

uccaccauca ucaaccccac caacgagacg gacgacaccg ccggcaacaa gccgaacuac      360

cagcggaagc cccucgugag cuucaaggag gaccccaccc ccuccgacaa cccguucagc      420

aagcuguaca aggagaccau cgagacguuc gacaacaacg aggaggaguc cagcuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccugga ccggaucgac      540

gagaagcuca gcgagauccu ggggaugcug cacacccucg uggucgccuc cgccggcccc      600

acgagcgcgc gcgacgggau ccgggacgcc augaucggcc ugcgcgagga gaugaucgag      660

aagauccgga ccgaggcccu gaugaccaac gaccgccucg aggccauggc gcggcugcgc      720

aacgaggagu ccgagaagau ggccaaggac accagcgacg aggugucccu gaaccccacg      780

agcgagaagc ucaacaaccu gcuggagggc aacgacagcg acaacgaccu cucccuggag      840

gacuucugag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10920
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10920
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgccaccaag      180

uuccucgagu ccaucaaggg caaguucacc ucccccaagg accccaagaa gaaggacucc      240

aucaucuccg ucaacuccau cgacaucgag gucaccaagg agucccccau caccuccaac      300

uccaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagcgcaagc cccucgucuc cuucaaggag gaccccaccc ccuccgacaa ccccuucucc      420

aagcucuaca aggagaccau cgagaccuuc gacaacaacg aggaggaguc cuccuacucc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg cccgccucga ccgcaucgac      540

gagaagcucu ccgagauccu cggcaugcuc cacacccucg ucgucgccuc cgccggcccc      600

accuccgccc gcgacggcau ccgcgacgcc augaucggcc uccgcgagga gaugaucgag      660

aagauccgca ccgaggcccu caugaccaac gaccgccucg aggccauggc ccgccuccgc      720

aacgaggagu ccgagaagau ggccaaggac accuccgacg aggucucccu caaccccacc      780

uccgagaagc ucaacaaccu ccucgagggc aacgacuccg acaacgaccu cucccucgag      840

gacuucugag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10921
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10921
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agcaaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuauaucag ugaacaguau cgauauugag gucacuaaag aaagcccaau cacguccaau      300

ucuaccauua ucaaccccac aaaugagacu gacgauaccg ccggaaacaa gccuaauuac      360

cagaggaaac cacucguuuc guucaaggag gaccccacac cuucagauaa cccauuuagc      420

aaacuuuaua aggaaaccau agagacuuuc gacaauaacg aagaggagag uuccuacucu      480

uaugaagaga ucaaugauca aacaaacgac aauauuaccg cgcggcugga ucgcaucgac      540

gaaaaguuga gcgagauuuu agguaugcug cauacgcuag ugguagcuuc cgccggcccc      600

acuucagcac gagaugggau ccgugacgcc augauaggac ucagagaaga gaugauugag      660

aaaaucagga ccgaagcucu gaugacaaac gaccggcuug aggcaauggc ccgccugaga      720

aaugaagaga gugaaaagau ggcuaaagau acuagcgacg aggugucuuu gaacccuacc      780

uccgagaagc ucaacaaucu gcuggaaggc aacgauucag acaaugaucu cagcuuagag      840

gacuuuugag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10922
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10922
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaguuccac ggcgaggacg ccaacaacag agccaccaag      180

uuccuggaga gcaucaaggg caaguucacc agccccaagg accccaagaa gaaggacagc      240

aucaucagcg ugaacagcau cgacaucgag gugaccaagg agagccccau caccagcaac      300

agcaccauca ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac      360

cagagaaagc cccuggugag cuucaaggag gaccccaccc ccagcgacaa ccccuucagc      420

aagcuguaca aggagaccau cgagaccuuc gacaacaacg aggaggagag cagcuacagc      480

uacgaggaga ucaacgacca gaccaacgac aacaucaccg ccagacugga cagaaucgac      540

gagaagcuga gcgagauccu gggcaugcug cacacccugg ugguggccag cgccggcccc      600

accagcgcca gagacggcau cagagacgcc augaucggcc ugagagagga gaugaucgag      660

aagaucagaa ccgaggcccu gaugaccaac gacagacugg aggccauggc cagacugaga      720

aacgaggaga gcgagaagau ggccaaggac accagcgacg aggugagccu gaaccccacc      780

agcgagaagc ugaacaaccu gcuggagggc aacgacagcg acaacgaccu gagccuggag      840

gacuucugag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10923
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10923
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaga aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agccaccaaa      180

uuccuggaaa gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu      240

auuaucagcg ugaacuccau ugauaucgag gucacgaaag aaucucccau uaccagcaau      300

uccacaauca ucaacccuac caaugagaca gacgauaccg cgggaaacaa gcccaauuac      360

cagcggaaac cucucguuuc uuucaaggag gaccccacac cuagcgauaa cccguuuucc      420

aaacuguaua aggaaaccau ugagacguuc gacaauaacg aagaggagag cucuuacucc      480

uaugaagaga ucaaugauca aaccaacgac aauauuacag cucgccuuga uagaaucgac      540

gaaaagcuga gcgagauucu cggcaugcug cauacccuug ugguggccuc ugccgggccc      600

acauccgcuc gggauggaau ccgcgacgcc augauuggcc ugagagaaga gaugaucgag      660

aaaauccgga ccgaagcucu caugacgaac gaccgccugg aggccauggc gagacugcgg      720

aaugaagaga gcgaaaagau ggccaaagau acaucugacg aggucucccu caacccuacc      780

agcgagaagc ugaacaaucu ucuggaaggg aacgauuccg acaaugaucu cucucuggag      840

gacuuuugag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10924
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10924
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcacc agaauuucac ggagaagacg caaacaacag agcaacaaaa      180

uucuuagaau caaucaaagg aaaauucaca agcccaaaag acccaaaaaa aaaagacuca      240

auaauaagcg uaaacucaau agacauagaa guaacaaaag aaagcccaau aacaagcaac      300

agcacaauaa uaaacccaac aaacgaaaca gaugacacag cuggaaauaa accaaacuac      360

caaagaaaac cccuagucag cuucaaagaa gaccccacac caucagacaa cccauucagc      420

aaacuauaua aagaaacaau agaaacauuu gacaacaacg aagaagaauc aucauacuca      480

uacgaagaaa uaaacgacca aacaaacgac aacauaaccg caagauuaga cagaauagau      540

gaaaaacuau cagaaauacu aggaaugcua cacacauuag uaguagcaag cgcaggacca      600

acaucagcaa gagacggaau aagagacgca augauaggac ucagagaaga aaugauagaa      660

aaaauaagaa cagaagcacu aaugacaaac gacagauuag aagcaauggc aagacuaaga      720

aaugaagaau cggaaaaaau ggcaaaagac acaucagacg aaguaagccu aaacccaaca      780

ucagaaaaau uaaauaaccu acuagaagga aacgacagcg acaacgacuu aucacuagaa      840

gacuucuaag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10925
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10925
gggagacucc ugucgggcgg aaguaggagg aguagaguuu aaaaacagua cucuuuuucc       60

gguucgggac guaguugaag caacgacaag ccggauaacc gcucuugaga caggaagcuu      120

accauggaaa aauucgcgcc cgaguuccac ggcgaggacg cgaacaaccg cgcgacaaag      180

uuccuagaau caaucaaggg caaauucacg agcccgaaag accccaagaa aaaggacuca      240

aucauaagcg ugaacucgau cgacaucgag gucacgaaag agagcccgau cacaagcaac      300

agcaccauaa uaaacccgac caacgaaaca gacgacaccg cgggcaacaa accgaacuac      360

caaagaaaac cgcucgugag cuucaaagaa gacccgaccc caagcgacaa cccguucuca      420

aaacuauaca aggaaacgau cgagaccuuc gacaacaacg aggaagagag cucguacucg      480

uacgaggaaa uaaacgacca aacaaacgac aacauaaccg cacgccuaga caggaucgac      540

gaaaaacucu cggaaauacu cgggaugcua cacacgcucg uggucgcgag cgcaggcccg      600

accucggcca gggacggcau cagggacgca augauaggcc ugcgagagga aaugaucgag      660

aaaauacgca ccgaagcacu caugaccaac gacagacucg aagccauggc caggcucagg      720

aacgaagaau ccgaaaagau ggcgaaagac accucggacg aggucucgcu caaccccacg      780

agcgagaaac ugaacaaccu acuggaaggg aacgacagcg acaacgaccu uucccucgag      840

gacuucugag gacuaguaau aaggaaacug uaugaauguc ugugggcagg aagugaagag      900

auccuucugu aaagguuuuu ggaauuaugu cugcugaaua auaaacuuuu uugaaauaau      960

aaaucuggua gaaaaaugag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10926
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10926
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaguu ugcuccugaa      120

uuccauggag aagaugcaaa caacagggcu acuaaauucc uagaaucaau aaagggcaaa      180

uucacaucac ccaaagaucc caagaaaaaa gauaguauca uaucugucaa cucaauagau      240

auagaaguaa ccaaagaaag cccuauaaca ucaaauucaa cuauuaucaa cccaacaaau      300

gagacagaug auacugcagg gaacaagccc aauuaucaaa gaaaaccucu aguaaguuuc      360

aaagaagacc cuacaccaag ugauaauccc uuuucuaaac uauacaaaga aaccauagaa      420

acauuugaua acaaugaaga agaauccagc uauucauacg aagaaauaaa ugaucagaca      480

aacgauaaua uaacagcaag auuagauagg auugaugaaa aauuaaguga aauacuagga      540

augcuucaca cauuaguagu ggcaagugca ggaccuacau cugcucggga ugguauaaga      600

gaugccauga uugguuuaag agaagaaaug auagaaaaaa ucagaacuga agcauuaaug      660

accaaugaca gauuagaagc uauggcaaga cucaggaaug aggaaaguga aaagauggca      720

aaagacacau cagaugaagu gucucucaau ccaacaucag agaaauugaa caaccuauug      780

gaagggaaug auagugacaa ugaucuauca cuugaagauu ucugaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10927
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10927
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcg accaaguucc uggagagcau caaggggaag      180

uucaccuccc cgaaggaccc caagaagaag gacagcauca ucuccgugaa cagcaucgac      240

aucgagguca cgaaggaguc ccccaucacc agcaacucca ccaucaucaa ccccaccaac      300

gagacggacg acaccgccgg caacaagccg aacuaccagc ggaagccccu cgugagcuuc      360

aaggaggacc ccacccccuc cgacaacccg uucagcaagc uguacaagga gaccaucgag      420

acguucgaca acaacgagga ggaguccagc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccuggaccgg aucgacgaga agcucagcga gauccugggg      540

augcugcaca cccucguggu cgccuccgcc ggccccacga gcgcgcgcga cgggauccgg      600

gacgccauga ucggccugcg cgaggagaug aucgagaaga uccggaccga ggcccugaug      660

accaacgacc gccucgaggc cauggcgcgg cugcgcaacg aggaguccga gaagauggcc      720

aaggacacca gcgacgaggu gucccugaac cccacgagcg agaagcucaa caaccugcug      780

gagggcaacg acagcgacaa cgaccucucc cuggaggacu ucugaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10928
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10928
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcc accaaguucc ucgaguccau caagggcaag      180

uucaccuccc ccaaggaccc caagaagaag gacuccauca ucuccgucaa cuccaucgac      240

aucgagguca ccaaggaguc ccccaucacc uccaacucca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccagc gcaagccccu cgucuccuuc      360

aaggaggacc ccacccccuc cgacaacccc uucuccaagc ucuacaagga gaccaucgag      420

accuucgaca acaacgagga ggaguccucc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccucgaccgc aucgacgaga agcucuccga gauccucggc      540

augcuccaca cccucgucgu cgccuccgcc ggccccaccu ccgcccgcga cggcauccgc      600

gacgccauga ucggccuccg cgaggagaug aucgagaaga uccgcaccga ggcccucaug      660

accaacgacc gccucgaggc cauggcccgc cuccgcaacg aggaguccga gaagauggcc      720

aaggacaccu ccgacgaggu cucccucaac cccaccuccg agaagcucaa caaccuccuc      780

gagggcaacg acuccgacaa cgaccucucc cucgaggacu ucugaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10929
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10929
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagca accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua uaucagugaa caguaucgau      240

auugagguca cuaaagaaag cccaaucacg uccaauucua ccauuaucaa ccccacaaau      300

gagacugacg auaccgccgg aaacaagccu aauuaccaga ggaaaccacu cguuucguuc      360

aaggaggacc ccacaccuuc agauaaccca uuuagcaaac uuuauaagga aaccauagag      420

acuuucgaca auaacgaaga ggagaguucc uacucuuaug aagagaucaa ugaucaaaca      480

aacgacaaua uuaccgcgcg gcuggaucgc aucgacgaaa aguugagcga gauuuuaggu      540

augcugcaua cgcuaguggu agcuuccgcc ggccccacuu cagcacgaga ugggauccgu      600

gacgccauga uaggacucag agaagagaug auugagaaaa ucaggaccga agcucugaug      660

acaaacgacc ggcuugaggc aauggcccgc cugagaaaug aagagaguga aaagauggcu      720

aaagauacua gcgacgaggu gucuuugaac ccuaccuccg agaagcucaa caaucugcug      780

gaaggcaacg auucagacaa ugaucucagc uuagaggacu uuugaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10930
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10930
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caacagagcc accaaguucc uggagagcau caagggcaag      180

uucaccagcc ccaaggaccc caagaagaag gacagcauca ucagcgugaa cagcaucgac      240

aucgagguga ccaaggagag ccccaucacc agcaacagca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccaga gaaagccccu ggugagcuuc      360

aaggaggacc ccacccccag cgacaacccc uucagcaagc uguacaagga gaccaucgag      420

accuucgaca acaacgagga ggagagcagc uacagcuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgccag acuggacaga aucgacgaga agcugagcga gauccugggc      540

augcugcaca cccugguggu ggccagcgcc ggccccacca gcgccagaga cggcaucaga      600

gacgccauga ucggccugag agaggagaug aucgagaaga ucagaaccga ggcccugaug      660

accaacgaca gacuggaggc cauggccaga cugagaaacg aggagagcga gaagauggcc      720

aaggacacca gcgacgaggu gagccugaac cccaccagcg agaagcugaa caaccugcug      780

gagggcaacg acagcgacaa cgaccugagc cuggaggacu ucugaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10931
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10931
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagcc accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua ucagcgugaa cuccauugau      240

aucgagguca cgaaagaauc ucccauuacc agcaauucca caaucaucaa cccuaccaau      300

gagacagacg auaccgcggg aaacaagccc aauuaccagc ggaaaccucu cguuucuuuc      360

aaggaggacc ccacaccuag cgauaacccg uuuuccaaac uguauaagga aaccauugag      420

acguucgaca auaacgaaga ggagagcucu uacuccuaug aagagaucaa ugaucaaacc      480

aacgacaaua uuacagcucg ccuugauaga aucgacgaaa agcugagcga gauucucggc      540

augcugcaua cccuuguggu ggccucugcc gggcccacau ccgcucggga uggaauccgc      600

gacgccauga uuggccugag agaagagaug aucgagaaaa uccggaccga agcucucaug      660

acgaacgacc gccuggaggc cauggcgaga cugcggaaug aagagagcga aaagauggcc      720

aaagauacau cugacgaggu cucccucaac ccuaccagcg agaagcugaa caaucuucug      780

gaagggaacg auuccgacaa ugaucucucu cuggaggacu uuugaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10932
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10932
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcaccagaa      120

uuucacggag aagacgcaaa caacagagca acaaaauucu uagaaucaau caaaggaaaa      180

uucacaagcc caaaagaccc aaaaaaaaaa gacucaauaa uaagcguaaa cucaauagac      240

auagaaguaa caaaagaaag cccaauaaca agcaacagca caauaauaaa cccaacaaac      300

gaaacagaug acacagcugg aaauaaacca aacuaccaaa gaaaaccccu agucagcuuc      360

aaagaagacc ccacaccauc agacaaccca uucagcaaac uauauaaaga aacaauagaa      420

acauuugaca acaacgaaga agaaucauca uacucauacg aagaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcaag auuagacaga auagaugaaa aacuaucaga aauacuagga      540

augcuacaca cauuaguagu agcaagcgca ggaccaacau cagcaagaga cggaauaaga      600

gacgcaauga uaggacucag agaagaaaug auagaaaaaa uaagaacaga agcacuaaug      660

acaaacgaca gauuagaagc aauggcaaga cuaagaaaug aagaaucgga aaaaauggca      720

aaagacacau cagacgaagu aagccuaaac ccaacaucag aaaaauuaaa uaaccuacua      780

gaaggaaacg acagcgacaa cgacuuauca cuagaagacu ucuaaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10933
<211>  1088
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design g-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10933
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcgcccgag      120

uuccacggcg aggacgcgaa caaccgcgcg acaaaguucc uagaaucaau caagggcaaa      180

uucacgagcc cgaaagaccc caagaaaaag gacucaauca uaagcgugaa cucgaucgac      240

aucgagguca cgaaagagag cccgaucaca agcaacagca ccauaauaaa cccgaccaac      300

gaaacagacg acaccgcggg caacaaaccg aacuaccaaa gaaaaccgcu cgugagcuuc      360

aaagaagacc cgaccccaag cgacaacccg uucucaaaac uauacaagga aacgaucgag      420

accuucgaca acaacgagga agagagcucg uacucguacg aggaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcacg ccuagacagg aucgacgaaa aacucucgga aauacucggg      540

augcuacaca cgcucguggu cgcgagcgca ggcccgaccu cggccaggga cggcaucagg      600

gacgcaauga uaggccugcg agaggaaaug aucgagaaaa uacgcaccga agcacucaug      660

accaacgaca gacucgaagc cauggccagg cucaggaacg aagaauccga aaagauggcg      720

aaagacaccu cggacgaggu cucgcucaac cccacgagcg agaaacugaa caaccuacug      780

gaagggaacg acagcgacaa cgaccuuucc cucgaggacu ucugaggacu aguaauaagg      840

aaacuguaug aaugucugug ggcaggaagu gaagagaucc uucuguaaag guuuuuggaa      900

uuaugucugc ugaauaauaa acuuuuuuga aauaauaaau cugguagaaa aaugagaucu      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca     1080

ccagaauu                                                              1088


<210>  10934
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10934
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaguu ugcuccugaa      120

uuccauggag aagaugcaaa caacagggcu acuaaauucc uagaaucaau aaagggcaaa      180

uucacaucac ccaaagaucc caagaaaaaa gauaguauca uaucugucaa cucaauagau      240

auagaaguaa ccaaagaaag cccuauaaca ucaaauucaa cuauuaucaa cccaacaaau      300

gagacagaug auacugcagg gaacaagccc aauuaucaaa gaaaaccucu aguaaguuuc      360

aaagaagacc cuacaccaag ugauaauccc uuuucuaaac uauacaaaga aaccauagaa      420

acauuugaua acaaugaaga agaauccagc uauucauacg aagaaauaaa ugaucagaca      480

aacgauaaua uaacagcaag auuagauagg auugaugaaa aauuaaguga aauacuagga      540

augcuucaca cauuaguagu ggcaagugca ggaccuacau cugcucggga ugguauaaga      600

gaugccauga uugguuuaag agaagaaaug auagaaaaaa ucagaacuga agcauuaaug      660

accaaugaca gauuagaagc uauggcaaga cucaggaaug aggaaaguga aaagauggca      720

aaagacacau cagaugaagu gucucucaau ccaacaucag agaaauugaa caaccuauug      780

gaagggaaug auagugacaa ugaucuauca cuugaagauu ucugaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10935
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10935
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcg accaaguucc uggagagcau caaggggaag      180

uucaccuccc cgaaggaccc caagaagaag gacagcauca ucuccgugaa cagcaucgac      240

aucgagguca cgaaggaguc ccccaucacc agcaacucca ccaucaucaa ccccaccaac      300

gagacggacg acaccgccgg caacaagccg aacuaccagc ggaagccccu cgugagcuuc      360

aaggaggacc ccacccccuc cgacaacccg uucagcaagc uguacaagga gaccaucgag      420

acguucgaca acaacgagga ggaguccagc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccuggaccgg aucgacgaga agcucagcga gauccugggg      540

augcugcaca cccucguggu cgccuccgcc ggccccacga gcgcgcgcga cgggauccgg      600

gacgccauga ucggccugcg cgaggagaug aucgagaaga uccggaccga ggcccugaug      660

accaacgacc gccucgaggc cauggcgcgg cugcgcaacg aggaguccga gaagauggcc      720

aaggacacca gcgacgaggu gucccugaac cccacgagcg agaagcucaa caaccugcug      780

gagggcaacg acagcgacaa cgaccucucc cuggaggacu ucugaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10936
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10936
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcc accaaguucc ucgaguccau caagggcaag      180

uucaccuccc ccaaggaccc caagaagaag gacuccauca ucuccgucaa cuccaucgac      240

aucgagguca ccaaggaguc ccccaucacc uccaacucca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccagc gcaagccccu cgucuccuuc      360

aaggaggacc ccacccccuc cgacaacccc uucuccaagc ucuacaagga gaccaucgag      420

accuucgaca acaacgagga ggaguccucc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccucgaccgc aucgacgaga agcucuccga gauccucggc      540

augcuccaca cccucgucgu cgccuccgcc ggccccaccu ccgcccgcga cggcauccgc      600

gacgccauga ucggccuccg cgaggagaug aucgagaaga uccgcaccga ggcccucaug      660

accaacgacc gccucgaggc cauggcccgc cuccgcaacg aggaguccga gaagauggcc      720

aaggacaccu ccgacgaggu cucccucaac cccaccuccg agaagcucaa caaccuccuc      780

gagggcaacg acuccgacaa cgaccucucc cucgaggacu ucugaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10937
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10937
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagca accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua uaucagugaa caguaucgau      240

auugagguca cuaaagaaag cccaaucacg uccaauucua ccauuaucaa ccccacaaau      300

gagacugacg auaccgccgg aaacaagccu aauuaccaga ggaaaccacu cguuucguuc      360

aaggaggacc ccacaccuuc agauaaccca uuuagcaaac uuuauaagga aaccauagag      420

acuuucgaca auaacgaaga ggagaguucc uacucuuaug aagagaucaa ugaucaaaca      480

aacgacaaua uuaccgcgcg gcuggaucgc aucgacgaaa aguugagcga gauuuuaggu      540

augcugcaua cgcuaguggu agcuuccgcc ggccccacuu cagcacgaga ugggauccgu      600

gacgccauga uaggacucag agaagagaug auugagaaaa ucaggaccga agcucugaug      660

acaaacgacc ggcuugaggc aauggcccgc cugagaaaug aagagaguga aaagauggcu      720

aaagauacua gcgacgaggu gucuuugaac ccuaccuccg agaagcucaa caaucugcug      780

gaaggcaacg auucagacaa ugaucucagc uuagaggacu uuugaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10938
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10938
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caacagagcc accaaguucc uggagagcau caagggcaag      180

uucaccagcc ccaaggaccc caagaagaag gacagcauca ucagcgugaa cagcaucgac      240

aucgagguga ccaaggagag ccccaucacc agcaacagca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccaga gaaagccccu ggugagcuuc      360

aaggaggacc ccacccccag cgacaacccc uucagcaagc uguacaagga gaccaucgag      420

accuucgaca acaacgagga ggagagcagc uacagcuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgccag acuggacaga aucgacgaga agcugagcga gauccugggc      540

augcugcaca cccugguggu ggccagcgcc ggccccacca gcgccagaga cggcaucaga      600

gacgccauga ucggccugag agaggagaug aucgagaaga ucagaaccga ggcccugaug      660

accaacgaca gacuggaggc cauggccaga cugagaaacg aggagagcga gaagauggcc      720

aaggacacca gcgacgaggu gagccugaac cccaccagcg agaagcugaa caaccugcug      780

gagggcaacg acagcgacaa cgaccugagc cuggaggacu ucugaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10939
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10939
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagcc accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua ucagcgugaa cuccauugau      240

aucgagguca cgaaagaauc ucccauuacc agcaauucca caaucaucaa cccuaccaau      300

gagacagacg auaccgcggg aaacaagccc aauuaccagc ggaaaccucu cguuucuuuc      360

aaggaggacc ccacaccuag cgauaacccg uuuuccaaac uguauaagga aaccauugag      420

acguucgaca auaacgaaga ggagagcucu uacuccuaug aagagaucaa ugaucaaacc      480

aacgacaaua uuacagcucg ccuugauaga aucgacgaaa agcugagcga gauucucggc      540

augcugcaua cccuuguggu ggccucugcc gggcccacau ccgcucggga uggaauccgc      600

gacgccauga uuggccugag agaagagaug aucgagaaaa uccggaccga agcucucaug      660

acgaacgacc gccuggaggc cauggcgaga cugcggaaug aagagagcga aaagauggcc      720

aaagauacau cugacgaggu cucccucaac ccuaccagcg agaagcugaa caaucuucug      780

gaagggaacg auuccgacaa ugaucucucu cuggaggacu uuugaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10940
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10940
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcaccagaa      120

uuucacggag aagacgcaaa caacagagca acaaaauucu uagaaucaau caaaggaaaa      180

uucacaagcc caaaagaccc aaaaaaaaaa gacucaauaa uaagcguaaa cucaauagac      240

auagaaguaa caaaagaaag cccaauaaca agcaacagca caauaauaaa cccaacaaac      300

gaaacagaug acacagcugg aaauaaacca aacuaccaaa gaaaaccccu agucagcuuc      360

aaagaagacc ccacaccauc agacaaccca uucagcaaac uauauaaaga aacaauagaa      420

acauuugaca acaacgaaga agaaucauca uacucauacg aagaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcaag auuagacaga auagaugaaa aacuaucaga aauacuagga      540

augcuacaca cauuaguagu agcaagcgca ggaccaacau cagcaagaga cggaauaaga      600

gacgcaauga uaggacucag agaagaaaug auagaaaaaa uaagaacaga agcacuaaug      660

acaaacgaca gauuagaagc aauggcaaga cuaagaaaug aagaaucgga aaaaauggca      720

aaagacacau cagacgaagu aagccuaaac ccaacaucag aaaaauuaaa uaaccuacua      780

gaaggaaacg acagcgacaa cgacuuauca cuagaagacu ucuaaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10941
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10941
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcgcccgag      120

uuccacggcg aggacgcgaa caaccgcgcg acaaaguucc uagaaucaau caagggcaaa      180

uucacgagcc cgaaagaccc caagaaaaag gacucaauca uaagcgugaa cucgaucgac      240

aucgagguca cgaaagagag cccgaucaca agcaacagca ccauaauaaa cccgaccaac      300

gaaacagacg acaccgcggg caacaaaccg aacuaccaaa gaaaaccgcu cgugagcuuc      360

aaagaagacc cgaccccaag cgacaacccg uucucaaaac uauacaagga aacgaucgag      420

accuucgaca acaacgagga agagagcucg uacucguacg aggaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcacg ccuagacagg aucgacgaaa aacucucgga aauacucggg      540

augcuacaca cgcucguggu cgcgagcgca ggcccgaccu cggccaggga cggcaucagg      600

gacgcaauga uaggccugcg agaggaaaug aucgagaaaa uacgcaccga agcacucaug      660

accaacgaca gacucgaagc cauggccagg cucaggaacg aagaauccga aaagauggcg      720

aaagacaccu cggacgaggu cucgcucaac cccacgagcg agaaacugaa caaccuacug      780

gaagggaacg acagcgacaa cgaccuuucc cucgaggacu ucugaggacu aguacuggcu      840

gcaucucccu uuccucuguc cuccauccuu cucccaggau ggugaagggg gaccugguac      900

ccagugaucc ccaccccagg auccuaaauc augacuuacc ugcuaauaaa aacucauugg      960

aaaagugaga agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1080

gcucuuuuca gagccaccag aauu                                            1104


<210>  10942
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10942
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaguu ugcuccugaa      120

uuccauggag aagaugcaaa caacagggcu acuaaauucc uagaaucaau aaagggcaaa      180

uucacaucac ccaaagaucc caagaaaaaa gauaguauca uaucugucaa cucaauagau      240

auagaaguaa ccaaagaaag cccuauaaca ucaaauucaa cuauuaucaa cccaacaaau      300

gagacagaug auacugcagg gaacaagccc aauuaucaaa gaaaaccucu aguaaguuuc      360

aaagaagacc cuacaccaag ugauaauccc uuuucuaaac uauacaaaga aaccauagaa      420

acauuugaua acaaugaaga agaauccagc uauucauacg aagaaauaaa ugaucagaca      480

aacgauaaua uaacagcaag auuagauagg auugaugaaa aauuaaguga aauacuagga      540

augcuucaca cauuaguagu ggcaagugca ggaccuacau cugcucggga ugguauaaga      600

gaugccauga uugguuuaag agaagaaaug auagaaaaaa ucagaacuga agcauuaaug      660

accaaugaca gauuagaagc uauggcaaga cucaggaaug aggaaaguga aaagauggca      720

aaagacacau cagaugaagu gucucucaau ccaacaucag agaaauugaa caaccuauug      780

gaagggaaug auagugacaa ugaucuauca cuugaagauu ucugaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10943
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10943
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcg accaaguucc uggagagcau caaggggaag      180

uucaccuccc cgaaggaccc caagaagaag gacagcauca ucuccgugaa cagcaucgac      240

aucgagguca cgaaggaguc ccccaucacc agcaacucca ccaucaucaa ccccaccaac      300

gagacggacg acaccgccgg caacaagccg aacuaccagc ggaagccccu cgugagcuuc      360

aaggaggacc ccacccccuc cgacaacccg uucagcaagc uguacaagga gaccaucgag      420

acguucgaca acaacgagga ggaguccagc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccuggaccgg aucgacgaga agcucagcga gauccugggg      540

augcugcaca cccucguggu cgccuccgcc ggccccacga gcgcgcgcga cgggauccgg      600

gacgccauga ucggccugcg cgaggagaug aucgagaaga uccggaccga ggcccugaug      660

accaacgacc gccucgaggc cauggcgcgg cugcgcaacg aggaguccga gaagauggcc      720

aaggacacca gcgacgaggu gucccugaac cccacgagcg agaagcucaa caaccugcug      780

gagggcaacg acagcgacaa cgaccucucc cuggaggacu ucugaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10944
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10944
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcc accaaguucc ucgaguccau caagggcaag      180

uucaccuccc ccaaggaccc caagaagaag gacuccauca ucuccgucaa cuccaucgac      240

aucgagguca ccaaggaguc ccccaucacc uccaacucca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccagc gcaagccccu cgucuccuuc      360

aaggaggacc ccacccccuc cgacaacccc uucuccaagc ucuacaagga gaccaucgag      420

accuucgaca acaacgagga ggaguccucc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccucgaccgc aucgacgaga agcucuccga gauccucggc      540

augcuccaca cccucgucgu cgccuccgcc ggccccaccu ccgcccgcga cggcauccgc      600

gacgccauga ucggccuccg cgaggagaug aucgagaaga uccgcaccga ggcccucaug      660

accaacgacc gccucgaggc cauggcccgc cuccgcaacg aggaguccga gaagauggcc      720

aaggacaccu ccgacgaggu cucccucaac cccaccuccg agaagcucaa caaccuccuc      780

gagggcaacg acuccgacaa cgaccucucc cucgaggacu ucugaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10945
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10945
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagca accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua uaucagugaa caguaucgau      240

auugagguca cuaaagaaag cccaaucacg uccaauucua ccauuaucaa ccccacaaau      300

gagacugacg auaccgccgg aaacaagccu aauuaccaga ggaaaccacu cguuucguuc      360

aaggaggacc ccacaccuuc agauaaccca uuuagcaaac uuuauaagga aaccauagag      420

acuuucgaca auaacgaaga ggagaguucc uacucuuaug aagagaucaa ugaucaaaca      480

aacgacaaua uuaccgcgcg gcuggaucgc aucgacgaaa aguugagcga gauuuuaggu      540

augcugcaua cgcuaguggu agcuuccgcc ggccccacuu cagcacgaga ugggauccgu      600

gacgccauga uaggacucag agaagagaug auugagaaaa ucaggaccga agcucugaug      660

acaaacgacc ggcuugaggc aauggcccgc cugagaaaug aagagaguga aaagauggcu      720

aaagauacua gcgacgaggu gucuuugaac ccuaccuccg agaagcucaa caaucugcug      780

gaaggcaacg auucagacaa ugaucucagc uuagaggacu uuugaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10946
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10946
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caacagagcc accaaguucc uggagagcau caagggcaag      180

uucaccagcc ccaaggaccc caagaagaag gacagcauca ucagcgugaa cagcaucgac      240

aucgagguga ccaaggagag ccccaucacc agcaacagca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccaga gaaagccccu ggugagcuuc      360

aaggaggacc ccacccccag cgacaacccc uucagcaagc uguacaagga gaccaucgag      420

accuucgaca acaacgagga ggagagcagc uacagcuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgccag acuggacaga aucgacgaga agcugagcga gauccugggc      540

augcugcaca cccugguggu ggccagcgcc ggccccacca gcgccagaga cggcaucaga      600

gacgccauga ucggccugag agaggagaug aucgagaaga ucagaaccga ggcccugaug      660

accaacgaca gacuggaggc cauggccaga cugagaaacg aggagagcga gaagauggcc      720

aaggacacca gcgacgaggu gagccugaac cccaccagcg agaagcugaa caaccugcug      780

gagggcaacg acagcgacaa cgaccugagc cuggaggacu ucugaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10947
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10947
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagcc accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua ucagcgugaa cuccauugau      240

aucgagguca cgaaagaauc ucccauuacc agcaauucca caaucaucaa cccuaccaau      300

gagacagacg auaccgcggg aaacaagccc aauuaccagc ggaaaccucu cguuucuuuc      360

aaggaggacc ccacaccuag cgauaacccg uuuuccaaac uguauaagga aaccauugag      420

acguucgaca auaacgaaga ggagagcucu uacuccuaug aagagaucaa ugaucaaacc      480

aacgacaaua uuacagcucg ccuugauaga aucgacgaaa agcugagcga gauucucggc      540

augcugcaua cccuuguggu ggccucugcc gggcccacau ccgcucggga uggaauccgc      600

gacgccauga uuggccugag agaagagaug aucgagaaaa uccggaccga agcucucaug      660

acgaacgacc gccuggaggc cauggcgaga cugcggaaug aagagagcga aaagauggcc      720

aaagauacau cugacgaggu cucccucaac ccuaccagcg agaagcugaa caaucuucug      780

gaagggaacg auuccgacaa ugaucucucu cuggaggacu uuugaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10948
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10948
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcaccagaa      120

uuucacggag aagacgcaaa caacagagca acaaaauucu uagaaucaau caaaggaaaa      180

uucacaagcc caaaagaccc aaaaaaaaaa gacucaauaa uaagcguaaa cucaauagac      240

auagaaguaa caaaagaaag cccaauaaca agcaacagca caauaauaaa cccaacaaac      300

gaaacagaug acacagcugg aaauaaacca aacuaccaaa gaaaaccccu agucagcuuc      360

aaagaagacc ccacaccauc agacaaccca uucagcaaac uauauaaaga aacaauagaa      420

acauuugaca acaacgaaga agaaucauca uacucauacg aagaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcaag auuagacaga auagaugaaa aacuaucaga aauacuagga      540

augcuacaca cauuaguagu agcaagcgca ggaccaacau cagcaagaga cggaauaaga      600

gacgcaauga uaggacucag agaagaaaug auagaaaaaa uaagaacaga agcacuaaug      660

acaaacgaca gauuagaagc aauggcaaga cuaagaaaug aagaaucgga aaaaauggca      720

aaagacacau cagacgaagu aagccuaaac ccaacaucag aaaaauuaaa uaaccuacua      780

gaaggaaacg acagcgacaa cgacuuauca cuagaagacu ucuaaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10949
<211>  1320
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10949
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcgcccgag      120

uuccacggcg aggacgcgaa caaccgcgcg acaaaguucc uagaaucaau caagggcaaa      180

uucacgagcc cgaaagaccc caagaaaaag gacucaauca uaagcgugaa cucgaucgac      240

aucgagguca cgaaagagag cccgaucaca agcaacagca ccauaauaaa cccgaccaac      300

gaaacagacg acaccgcggg caacaaaccg aacuaccaaa gaaaaccgcu cgugagcuuc      360

aaagaagacc cgaccccaag cgacaacccg uucucaaaac uauacaagga aacgaucgag      420

accuucgaca acaacgagga agagagcucg uacucguacg aggaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcacg ccuagacagg aucgacgaaa aacucucgga aauacucggg      540

augcuacaca cgcucguggu cgcgagcgca ggcccgaccu cggccaggga cggcaucagg      600

gacgcaauga uaggccugcg agaggaaaug aucgagaaaa uacgcaccga agcacucaug      660

accaacgaca gacucgaagc cauggccagg cucaggaacg aagaauccga aaagauggcg      720

aaagacaccu cggacgaggu cucgcucaac cccacgagcg agaaacugaa caaccuacug      780

gaagggaacg acagcgacaa cgaccuuucc cucgaggacu ucugaggacu agugaaggga      840

acacccaaau uuaauucagc cuuaagcaca auuaauuaag agugaaacgu aauuguacaa      900

gcaguugguc acccaccaua gggcaugauc aacaccgcaa ccuuuccuuu uucccccagu      960

gauucugaaa aaccccucuu cccuucagcu ugcuuagaug uuccaaauuu aguaagcuua     1020

aggcggccua cagaagaaaa agaaaaaaaa ggccacaaaa guucccucuc acuuucagua     1080

aauaaaauaa aagcagcaac agaaauaaag aaauaaauga aauucaaaau gaaauaaaua     1140

uuguguugug cagcauuaaa aaaucaauaa aaauuaaaaa ugagcaagau cuaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1260

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1320


<210>  10950
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10950
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaguu ugcuccugaa      120

uuccauggag aagaugcaaa caacagggcu acuaaauucc uagaaucaau aaagggcaaa      180

uucacaucac ccaaagaucc caagaaaaaa gauaguauca uaucugucaa cucaauagau      240

auagaaguaa ccaaagaaag cccuauaaca ucaaauucaa cuauuaucaa cccaacaaau      300

gagacagaug auacugcagg gaacaagccc aauuaucaaa gaaaaccucu aguaaguuuc      360

aaagaagacc cuacaccaag ugauaauccc uuuucuaaac uauacaaaga aaccauagaa      420

acauuugaua acaaugaaga agaauccagc uauucauacg aagaaauaaa ugaucagaca      480

aacgauaaua uaacagcaag auuagauagg auugaugaaa aauuaaguga aauacuagga      540

augcuucaca cauuaguagu ggcaagugca ggaccuacau cugcucggga ugguauaaga      600

gaugccauga uugguuuaag agaagaaaug auagaaaaaa ucagaacuga agcauuaaug      660

accaaugaca gauuagaagc uauggcaaga cucaggaaug aggaaaguga aaagauggca      720

aaagacacau cagaugaagu gucucucaau ccaacaucag agaaauugaa caaccuauug      780

gaagggaaug auagugacaa ugaucuauca cuugaagauu ucugaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10951
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10951
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcg accaaguucc uggagagcau caaggggaag      180

uucaccuccc cgaaggaccc caagaagaag gacagcauca ucuccgugaa cagcaucgac      240

aucgagguca cgaaggaguc ccccaucacc agcaacucca ccaucaucaa ccccaccaac      300

gagacggacg acaccgccgg caacaagccg aacuaccagc ggaagccccu cgugagcuuc      360

aaggaggacc ccacccccuc cgacaacccg uucagcaagc uguacaagga gaccaucgag      420

acguucgaca acaacgagga ggaguccagc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccuggaccgg aucgacgaga agcucagcga gauccugggg      540

augcugcaca cccucguggu cgccuccgcc ggccccacga gcgcgcgcga cgggauccgg      600

gacgccauga ucggccugcg cgaggagaug aucgagaaga uccggaccga ggcccugaug      660

accaacgacc gccucgaggc cauggcgcgg cugcgcaacg aggaguccga gaagauggcc      720

aaggacacca gcgacgaggu gucccugaac cccacgagcg agaagcucaa caaccugcug      780

gagggcaacg acagcgacaa cgaccucucc cuggaggacu ucugaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10952
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10952
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caaccgcgcc accaaguucc ucgaguccau caagggcaag      180

uucaccuccc ccaaggaccc caagaagaag gacuccauca ucuccgucaa cuccaucgac      240

aucgagguca ccaaggaguc ccccaucacc uccaacucca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccagc gcaagccccu cgucuccuuc      360

aaggaggacc ccacccccuc cgacaacccc uucuccaagc ucuacaagga gaccaucgag      420

accuucgaca acaacgagga ggaguccucc uacuccuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgcccg ccucgaccgc aucgacgaga agcucuccga gauccucggc      540

augcuccaca cccucgucgu cgccuccgcc ggccccaccu ccgcccgcga cggcauccgc      600

gacgccauga ucggccuccg cgaggagaug aucgagaaga uccgcaccga ggcccucaug      660

accaacgacc gccucgaggc cauggcccgc cuccgcaacg aggaguccga gaagauggcc      720

aaggacaccu ccgacgaggu cucccucaac cccaccuccg agaagcucaa caaccuccuc      780

gagggcaacg acuccgacaa cgaccucucc cucgaggacu ucugaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10953
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10953
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagca accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua uaucagugaa caguaucgau      240

auugagguca cuaaagaaag cccaaucacg uccaauucua ccauuaucaa ccccacaaau      300

gagacugacg auaccgccgg aaacaagccu aauuaccaga ggaaaccacu cguuucguuc      360

aaggaggacc ccacaccuuc agauaaccca uuuagcaaac uuuauaagga aaccauagag      420

acuuucgaca auaacgaaga ggagaguucc uacucuuaug aagagaucaa ugaucaaaca      480

aacgacaaua uuaccgcgcg gcuggaucgc aucgacgaaa aguugagcga gauuuuaggu      540

augcugcaua cgcuaguggu agcuuccgcc ggccccacuu cagcacgaga ugggauccgu      600

gacgccauga uaggacucag agaagagaug auugagaaaa ucaggaccga agcucugaug      660

acaaacgacc ggcuugaggc aauggcccgc cugagaaaug aagagaguga aaagauggcu      720

aaagauacua gcgacgaggu gucuuugaac ccuaccuccg agaagcucaa caaucugcug      780

gaaggcaacg auucagacaa ugaucucagc uuagaggacu uuugaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10954
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10954
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgag      120

uuccacggcg aggacgccaa caacagagcc accaaguucc uggagagcau caagggcaag      180

uucaccagcc ccaaggaccc caagaagaag gacagcauca ucagcgugaa cagcaucgac      240

aucgagguga ccaaggagag ccccaucacc agcaacagca ccaucaucaa ccccaccaac      300

gagaccgacg acaccgccgg caacaagccc aacuaccaga gaaagccccu ggugagcuuc      360

aaggaggacc ccacccccag cgacaacccc uucagcaagc uguacaagga gaccaucgag      420

accuucgaca acaacgagga ggagagcagc uacagcuacg aggagaucaa cgaccagacc      480

aacgacaaca ucaccgccag acuggacaga aucgacgaga agcugagcga gauccugggc      540

augcugcaca cccugguggu ggccagcgcc ggccccacca gcgccagaga cggcaucaga      600

gacgccauga ucggccugag agaggagaug aucgagaaga ucagaaccga ggcccugaug      660

accaacgaca gacuggaggc cauggccaga cugagaaacg aggagagcga gaagauggcc      720

aaggacacca gcgacgaggu gagccugaac cccaccagcg agaagcugaa caaccugcug      780

gagggcaacg acagcgacaa cgaccugagc cuggaggacu ucugaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10955
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10955
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggagaaguu cgcccccgaa      120

uuucacggcg aggacgcuaa caauagagcc accaaauucc uggaaagcau caaggggaaa      180

uuuacauccc cuaaggaucc gaaaaagaag gacucuauua ucagcgugaa cuccauugau      240

aucgagguca cgaaagaauc ucccauuacc agcaauucca caaucaucaa cccuaccaau      300

gagacagacg auaccgcggg aaacaagccc aauuaccagc ggaaaccucu cguuucuuuc      360

aaggaggacc ccacaccuag cgauaacccg uuuuccaaac uguauaagga aaccauugag      420

acguucgaca auaacgaaga ggagagcucu uacuccuaug aagagaucaa ugaucaaacc      480

aacgacaaua uuacagcucg ccuugauaga aucgacgaaa agcugagcga gauucucggc      540

augcugcaua cccuuguggu ggccucugcc gggcccacau ccgcucggga uggaauccgc      600

gacgccauga uuggccugag agaagagaug aucgagaaaa uccggaccga agcucucaug      660

acgaacgacc gccuggaggc cauggcgaga cugcggaaug aagagagcga aaagauggcc      720

aaagauacau cugacgaggu cucccucaac ccuaccagcg agaagcugaa caaucuucug      780

gaagggaacg auuccgacaa ugaucucucu cuggaggacu uuugaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10956
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10956
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcaccagaa      120

uuucacggag aagacgcaaa caacagagca acaaaauucu uagaaucaau caaaggaaaa      180

uucacaagcc caaaagaccc aaaaaaaaaa gacucaauaa uaagcguaaa cucaauagac      240

auagaaguaa caaaagaaag cccaauaaca agcaacagca caauaauaaa cccaacaaac      300

gaaacagaug acacagcugg aaauaaacca aacuaccaaa gaaaaccccu agucagcuuc      360

aaagaagacc ccacaccauc agacaaccca uucagcaaac uauauaaaga aacaauagaa      420

acauuugaca acaacgaaga agaaucauca uacucauacg aagaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcaag auuagacaga auagaugaaa aacuaucaga aauacuagga      540

augcuacaca cauuaguagu agcaagcgca ggaccaacau cagcaagaga cggaauaaga      600

gacgcaauga uaggacucag agaagaaaug auagaaaaaa uaagaacaga agcacuaaug      660

acaaacgaca gauuagaagc aauggcaaga cuaagaaaug aagaaucgga aaaaauggca      720

aaagacacau cagacgaagu aagccuaaac ccaacaucag aaaaauuaaa uaaccuacua      780

gaaggaaacg acagcgacaa cgacuuauca cuagaagacu ucuaaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10957
<211>  1100
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10957
gggagacccg ugacccggaa guuguacggc uacgcgacuu ucccucccac aaacccucgc       60

gcccuuccuu uccuacuugg gcccggcaga aagcuuacca uggaaaaauu cgcgcccgag      120

uuccacggcg aggacgcgaa caaccgcgcg acaaaguucc uagaaucaau caagggcaaa      180

uucacgagcc cgaaagaccc caagaaaaag gacucaauca uaagcgugaa cucgaucgac      240

aucgagguca cgaaagagag cccgaucaca agcaacagca ccauaauaaa cccgaccaac      300

gaaacagacg acaccgcggg caacaaaccg aacuaccaaa gaaaaccgcu cgugagcuuc      360

aaagaagacc cgaccccaag cgacaacccg uucucaaaac uauacaagga aacgaucgag      420

accuucgaca acaacgagga agagagcucg uacucguacg aggaaauaaa cgaccaaaca      480

aacgacaaca uaaccgcacg ccuagacagg aucgacgaaa aacucucgga aauacucggg      540

augcuacaca cgcucguggu cgcgagcgca ggcccgaccu cggccaggga cggcaucagg      600

gacgcaauga uaggccugcg agaggaaaug aucgagaaaa uacgcaccga agcacucaug      660

accaacgaca gacucgaagc cauggccagg cucaggaacg aagaauccga aaagauggcg      720

aaagacaccu cggacgaggu cucgcucaac cccacgagcg agaaacugaa caaccuacug      780

gaagggaacg acagcgacaa cgaccuuucc cucgaggacu ucugaggacu aguggaagca      840

uuuuccuggc ugauuaaaag aaauuacuca gcuaugguca ucuguuccug uuagaaggcu      900

augcagcaua uuauauacua ugcgcauguu augaaaugca uaauaaaaaa uuuuaaaaaa      960

ucuaaaagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc     1080

uuuucagagc caccagaauu                                                 1100


<210>  10958
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10958
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaguuugcuc cugaauucca uggagaagau gcaaacaaca gggcuacuaa auuccuagaa      240

ucaauaaagg gcaaauucac aucacccaaa gaucccaaga aaaaagauag uaucauaucu      300

gucaacucaa uagauauaga aguaaccaaa gaaagcccua uaacaucaaa uucaacuauu      360

aucaacccaa caaaugagac agaugauacu gcagggaaca agcccaauua ucaaagaaaa      420

ccucuaguaa guuucaaaga agacccuaca ccaagugaua aucccuuuuc uaaacuauac      480

aaagaaacca uagaaacauu ugauaacaau gaagaagaau ccagcuauuc auacgaagaa      540

auaaaugauc agacaaacga uaauauaaca gcaagauuag auaggauuga ugaaaaauua      600

agugaaauac uaggaaugcu ucacacauua guaguggcaa gugcaggacc uacaucugcu      660

cgggauggua uaagagaugc caugauuggu uuaagagaag aaaugauaga aaaaaucaga      720

acugaagcau uaaugaccaa ugacagauua gaagcuaugg caagacucag gaaugaggaa      780

agugaaaaga uggcaaaaga cacaucagau gaagugucuc ucaauccaac aucagagaaa      840

uugaacaacc uauuggaagg gaaugauagu gacaaugauc uaucacuuga agauuucuga      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10959
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10959
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgcgaccaa guuccuggag      240

agcaucaagg ggaaguucac cuccccgaag gaccccaaga agaaggacag caucaucucc      300

gugaacagca ucgacaucga ggucacgaag gaguccccca ucaccagcaa cuccaccauc      360

aucaacccca ccaacgagac ggacgacacc gccggcaaca agccgaacua ccagcggaag      420

ccccucguga gcuucaagga ggaccccacc cccuccgaca acccguucag caagcuguac      480

aaggagacca ucgagacguu cgacaacaac gaggaggagu ccagcuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccugg accggaucga cgagaagcuc      600

agcgagaucc uggggaugcu gcacacccuc guggucgccu ccgccggccc cacgagcgcg      660

cgcgacggga uccgggacgc caugaucggc cugcgcgagg agaugaucga gaagauccgg      720

accgaggccc ugaugaccaa cgaccgccuc gaggccaugg cgcggcugcg caacgaggag      780

uccgagaaga uggccaagga caccagcgac gagguguccc ugaaccccac gagcgagaag      840

cucaacaacc ugcuggaggg caacgacagc gacaacgacc ucucccugga ggacuucuga      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10960
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10960
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgccaccaa guuccucgag      240

uccaucaagg gcaaguucac cucccccaag gaccccaaga agaaggacuc caucaucucc      300

gucaacucca ucgacaucga ggucaccaag gaguccccca ucaccuccaa cuccaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagcgcaag      420

ccccucgucu ccuucaagga ggaccccacc cccuccgaca accccuucuc caagcucuac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggagu ccuccuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccucg accgcaucga cgagaagcuc      600

uccgagaucc ucggcaugcu ccacacccuc gucgucgccu ccgccggccc caccuccgcc      660

cgcgacggca uccgcgacgc caugaucggc cuccgcgagg agaugaucga gaagauccgc      720

accgaggccc ucaugaccaa cgaccgccuc gaggccaugg cccgccuccg caacgaggag      780

uccgagaaga uggccaagga caccuccgac gaggucuccc ucaaccccac cuccgagaag      840

cucaacaacc uccucgaggg caacgacucc gacaacgacc ucucccucga ggacuucuga      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10961
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10961
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagcaaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuauauca      300

gugaacagua ucgauauuga ggucacuaaa gaaagcccaa ucacguccaa uucuaccauu      360

aucaacccca caaaugagac ugacgauacc gccggaaaca agccuaauua ccagaggaaa      420

ccacucguuu cguucaagga ggaccccaca ccuucagaua acccauuuag caaacuuuau      480

aaggaaacca uagagacuuu cgacaauaac gaagaggaga guuccuacuc uuaugaagag      540

aucaaugauc aaacaaacga caauauuacc gcgcggcugg aucgcaucga cgaaaaguug      600

agcgagauuu uagguaugcu gcauacgcua gugguagcuu ccgccggccc cacuucagca      660

cgagauggga uccgugacgc caugauagga cucagagaag agaugauuga gaaaaucagg      720

accgaagcuc ugaugacaaa cgaccggcuu gaggcaaugg cccgccugag aaaugaagag      780

agugaaaaga uggcuaaaga uacuagcgac gaggugucuu ugaacccuac cuccgagaag      840

cucaacaauc ugcuggaagg caacgauuca gacaaugauc ucagcuuaga ggacuuuuga      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10962
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10962
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaaca gagccaccaa guuccuggag      240

agcaucaagg gcaaguucac cagccccaag gaccccaaga agaaggacag caucaucagc      300

gugaacagca ucgacaucga ggugaccaag gagagcccca ucaccagcaa cagcaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagagaaag      420

ccccugguga gcuucaagga ggaccccacc cccagcgaca accccuucag caagcuguac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggaga gcagcuacag cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gccagacugg acagaaucga cgagaagcug      600

agcgagaucc ugggcaugcu gcacacccug gugguggcca gcgccggccc caccagcgcc      660

agagacggca ucagagacgc caugaucggc cugagagagg agaugaucga gaagaucaga      720

accgaggccc ugaugaccaa cgacagacug gaggccaugg ccagacugag aaacgaggag      780

agcgagaaga uggccaagga caccagcgac gaggugagcc ugaaccccac cagcgagaag      840

cugaacaacc ugcuggaggg caacgacagc gacaacgacc ugagccugga ggacuucuga      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10963
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10963
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagccaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuaucagc      300

gugaacucca uugauaucga ggucacgaaa gaaucuccca uuaccagcaa uuccacaauc      360

aucaacccua ccaaugagac agacgauacc gcgggaaaca agcccaauua ccagcggaaa      420

ccucucguuu cuuucaagga ggaccccaca ccuagcgaua acccguuuuc caaacuguau      480

aaggaaacca uugagacguu cgacaauaac gaagaggaga gcucuuacuc cuaugaagag      540

aucaaugauc aaaccaacga caauauuaca gcucgccuug auagaaucga cgaaaagcug      600

agcgagauuc ucggcaugcu gcauacccuu gugguggccu cugccgggcc cacauccgcu      660

cgggauggaa uccgcgacgc caugauuggc cugagagaag agaugaucga gaaaauccgg      720

accgaagcuc ucaugacgaa cgaccgccug gaggccaugg cgagacugcg gaaugaagag      780

agcgaaaaga uggccaaaga uacaucugac gaggucuccc ucaacccuac cagcgagaag      840

cugaacaauc uucuggaagg gaacgauucc gacaaugauc ucucucugga ggacuuuuga      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10964
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10964
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcac cagaauuuca cggagaagac gcaaacaaca gagcaacaaa auucuuagaa      240

ucaaucaaag gaaaauucac aagcccaaaa gacccaaaaa aaaaagacuc aauaauaagc      300

guaaacucaa uagacauaga aguaacaaaa gaaagcccaa uaacaagcaa cagcacaaua      360

auaaacccaa caaacgaaac agaugacaca gcuggaaaua aaccaaacua ccaaagaaaa      420

ccccuaguca gcuucaaaga agaccccaca ccaucagaca acccauucag caaacuauau      480

aaagaaacaa uagaaacauu ugacaacaac gaagaagaau caucauacuc auacgaagaa      540

auaaacgacc aaacaaacga caacauaacc gcaagauuag acagaauaga ugaaaaacua      600

ucagaaauac uaggaaugcu acacacauua guaguagcaa gcgcaggacc aacaucagca      660

agagacggaa uaagagacgc aaugauagga cucagagaag aaaugauaga aaaaauaaga      720

acagaagcac uaaugacaaa cgacagauua gaagcaaugg caagacuaag aaaugaagaa      780

ucggaaaaaa uggcaaaaga cacaucagac gaaguaagcc uaaacccaac aucagaaaaa      840

uuaaauaacc uacuagaagg aaacgacagc gacaacgacu uaucacuaga agacuucuaa      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10965
<211>  1163
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-4 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10965
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcgc ccgaguucca cggcgaggac gcgaacaacc gcgcgacaaa guuccuagaa      240

ucaaucaagg gcaaauucac gagcccgaaa gaccccaaga aaaaggacuc aaucauaagc      300

gugaacucga ucgacaucga ggucacgaaa gagagcccga ucacaagcaa cagcaccaua      360

auaaacccga ccaacgaaac agacgacacc gcgggcaaca aaccgaacua ccaaagaaaa      420

ccgcucguga gcuucaaaga agacccgacc ccaagcgaca acccguucuc aaaacuauac      480

aaggaaacga ucgagaccuu cgacaacaac gaggaagaga gcucguacuc guacgaggaa      540

auaaacgacc aaacaaacga caacauaacc gcacgccuag acaggaucga cgaaaaacuc      600

ucggaaauac ucgggaugcu acacacgcuc guggucgcga gcgcaggccc gaccucggcc      660

agggacggca ucagggacgc aaugauaggc cugcgagagg aaaugaucga gaaaauacgc      720

accgaagcac ucaugaccaa cgacagacuc gaagccaugg ccaggcucag gaacgaagaa      780

uccgaaaaga uggcgaaaga caccucggac gaggucucgc ucaaccccac gagcgagaaa      840

cugaacaacc uacuggaagg gaacgacagc gacaacgacc uuucccucga ggacuucuga      900

ggacuaguaa uaaggaaacu guaugaaugu cugugggcag gaagugaaga gauccuucug      960

uaaagguuuu uggaauuaug ucugcugaau aauaaacuuu uuugaaauaa uaaaucuggu     1020

agaaaaauga gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg     1140

cucuuuucag agccaccaga auu                                             1163


<210>  10966
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10966
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaguuugcuc cugaauucca uggagaagau gcaaacaaca gggcuacuaa auuccuagaa      240

ucaauaaagg gcaaauucac aucacccaaa gaucccaaga aaaaagauag uaucauaucu      300

gucaacucaa uagauauaga aguaaccaaa gaaagcccua uaacaucaaa uucaacuauu      360

aucaacccaa caaaugagac agaugauacu gcagggaaca agcccaauua ucaaagaaaa      420

ccucuaguaa guuucaaaga agacccuaca ccaagugaua aucccuuuuc uaaacuauac      480

aaagaaacca uagaaacauu ugauaacaau gaagaagaau ccagcuauuc auacgaagaa      540

auaaaugauc agacaaacga uaauauaaca gcaagauuag auaggauuga ugaaaaauua      600

agugaaauac uaggaaugcu ucacacauua guaguggcaa gugcaggacc uacaucugcu      660

cgggauggua uaagagaugc caugauuggu uuaagagaag aaaugauaga aaaaaucaga      720

acugaagcau uaaugaccaa ugacagauua gaagcuaugg caagacucag gaaugaggaa      780

agugaaaaga uggcaaaaga cacaucagau gaagugucuc ucaauccaac aucagagaaa      840

uugaacaacc uauuggaagg gaaugauagu gacaaugauc uaucacuuga agauuucuga      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10967
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10967
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgcgaccaa guuccuggag      240

agcaucaagg ggaaguucac cuccccgaag gaccccaaga agaaggacag caucaucucc      300

gugaacagca ucgacaucga ggucacgaag gaguccccca ucaccagcaa cuccaccauc      360

aucaacccca ccaacgagac ggacgacacc gccggcaaca agccgaacua ccagcggaag      420

ccccucguga gcuucaagga ggaccccacc cccuccgaca acccguucag caagcuguac      480

aaggagacca ucgagacguu cgacaacaac gaggaggagu ccagcuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccugg accggaucga cgagaagcuc      600

agcgagaucc uggggaugcu gcacacccuc guggucgccu ccgccggccc cacgagcgcg      660

cgcgacggga uccgggacgc caugaucggc cugcgcgagg agaugaucga gaagauccgg      720

accgaggccc ugaugaccaa cgaccgccuc gaggccaugg cgcggcugcg caacgaggag      780

uccgagaaga uggccaagga caccagcgac gagguguccc ugaaccccac gagcgagaag      840

cucaacaacc ugcuggaggg caacgacagc gacaacgacc ucucccugga ggacuucuga      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10968
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10968
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgccaccaa guuccucgag      240

uccaucaagg gcaaguucac cucccccaag gaccccaaga agaaggacuc caucaucucc      300

gucaacucca ucgacaucga ggucaccaag gaguccccca ucaccuccaa cuccaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagcgcaag      420

ccccucgucu ccuucaagga ggaccccacc cccuccgaca accccuucuc caagcucuac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggagu ccuccuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccucg accgcaucga cgagaagcuc      600

uccgagaucc ucggcaugcu ccacacccuc gucgucgccu ccgccggccc caccuccgcc      660

cgcgacggca uccgcgacgc caugaucggc cuccgcgagg agaugaucga gaagauccgc      720

accgaggccc ucaugaccaa cgaccgccuc gaggccaugg cccgccuccg caacgaggag      780

uccgagaaga uggccaagga caccuccgac gaggucuccc ucaaccccac cuccgagaag      840

cucaacaacc uccucgaggg caacgacucc gacaacgacc ucucccucga ggacuucuga      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10969
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10969
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagcaaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuauauca      300

gugaacagua ucgauauuga ggucacuaaa gaaagcccaa ucacguccaa uucuaccauu      360

aucaacccca caaaugagac ugacgauacc gccggaaaca agccuaauua ccagaggaaa      420

ccacucguuu cguucaagga ggaccccaca ccuucagaua acccauuuag caaacuuuau      480

aaggaaacca uagagacuuu cgacaauaac gaagaggaga guuccuacuc uuaugaagag      540

aucaaugauc aaacaaacga caauauuacc gcgcggcugg aucgcaucga cgaaaaguug      600

agcgagauuu uagguaugcu gcauacgcua gugguagcuu ccgccggccc cacuucagca      660

cgagauggga uccgugacgc caugauagga cucagagaag agaugauuga gaaaaucagg      720

accgaagcuc ugaugacaaa cgaccggcuu gaggcaaugg cccgccugag aaaugaagag      780

agugaaaaga uggcuaaaga uacuagcgac gaggugucuu ugaacccuac cuccgagaag      840

cucaacaauc ugcuggaagg caacgauuca gacaaugauc ucagcuuaga ggacuuuuga      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10970
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10970
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaaca gagccaccaa guuccuggag      240

agcaucaagg gcaaguucac cagccccaag gaccccaaga agaaggacag caucaucagc      300

gugaacagca ucgacaucga ggugaccaag gagagcccca ucaccagcaa cagcaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagagaaag      420

ccccugguga gcuucaagga ggaccccacc cccagcgaca accccuucag caagcuguac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggaga gcagcuacag cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gccagacugg acagaaucga cgagaagcug      600

agcgagaucc ugggcaugcu gcacacccug gugguggcca gcgccggccc caccagcgcc      660

agagacggca ucagagacgc caugaucggc cugagagagg agaugaucga gaagaucaga      720

accgaggccc ugaugaccaa cgacagacug gaggccaugg ccagacugag aaacgaggag      780

agcgagaaga uggccaagga caccagcgac gaggugagcc ugaaccccac cagcgagaag      840

cugaacaacc ugcuggaggg caacgacagc gacaacgacc ugagccugga ggacuucuga      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10971
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10971
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagccaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuaucagc      300

gugaacucca uugauaucga ggucacgaaa gaaucuccca uuaccagcaa uuccacaauc      360

aucaacccua ccaaugagac agacgauacc gcgggaaaca agcccaauua ccagcggaaa      420

ccucucguuu cuuucaagga ggaccccaca ccuagcgaua acccguuuuc caaacuguau      480

aaggaaacca uugagacguu cgacaauaac gaagaggaga gcucuuacuc cuaugaagag      540

aucaaugauc aaaccaacga caauauuaca gcucgccuug auagaaucga cgaaaagcug      600

agcgagauuc ucggcaugcu gcauacccuu gugguggccu cugccgggcc cacauccgcu      660

cgggauggaa uccgcgacgc caugauuggc cugagagaag agaugaucga gaaaauccgg      720

accgaagcuc ucaugacgaa cgaccgccug gaggccaugg cgagacugcg gaaugaagag      780

agcgaaaaga uggccaaaga uacaucugac gaggucuccc ucaacccuac cagcgagaag      840

cugaacaauc uucuggaagg gaacgauucc gacaaugauc ucucucugga ggacuuuuga      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10972
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10972
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcac cagaauuuca cggagaagac gcaaacaaca gagcaacaaa auucuuagaa      240

ucaaucaaag gaaaauucac aagcccaaaa gacccaaaaa aaaaagacuc aauaauaagc      300

guaaacucaa uagacauaga aguaacaaaa gaaagcccaa uaacaagcaa cagcacaaua      360

auaaacccaa caaacgaaac agaugacaca gcuggaaaua aaccaaacua ccaaagaaaa      420

ccccuaguca gcuucaaaga agaccccaca ccaucagaca acccauucag caaacuauau      480

aaagaaacaa uagaaacauu ugacaacaac gaagaagaau caucauacuc auacgaagaa      540

auaaacgacc aaacaaacga caacauaacc gcaagauuag acagaauaga ugaaaaacua      600

ucagaaauac uaggaaugcu acacacauua guaguagcaa gcgcaggacc aacaucagca      660

agagacggaa uaagagacgc aaugauagga cucagagaag aaaugauaga aaaaauaaga      720

acagaagcac uaaugacaaa cgacagauua gaagcaaugg caagacuaag aaaugaagaa      780

ucggaaaaaa uggcaaaaga cacaucagac gaaguaagcc uaaacccaac aucagaaaaa      840

uuaaauaacc uacuagaagg aaacgacagc gacaacgacu uaucacuaga agacuucuaa      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10973
<211>  1179
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design h-5 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10973
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcgc ccgaguucca cggcgaggac gcgaacaacc gcgcgacaaa guuccuagaa      240

ucaaucaagg gcaaauucac gagcccgaaa gaccccaaga aaaaggacuc aaucauaagc      300

gugaacucga ucgacaucga ggucacgaaa gagagcccga ucacaagcaa cagcaccaua      360

auaaacccga ccaacgaaac agacgacacc gcgggcaaca aaccgaacua ccaaagaaaa      420

ccgcucguga gcuucaaaga agacccgacc ccaagcgaca acccguucuc aaaacuauac      480

aaggaaacga ucgagaccuu cgacaacaac gaggaagaga gcucguacuc guacgaggaa      540

auaaacgacc aaacaaacga caacauaacc gcacgccuag acaggaucga cgaaaaacuc      600

ucggaaauac ucgggaugcu acacacgcuc guggucgcga gcgcaggccc gaccucggcc      660

agggacggca ucagggacgc aaugauaggc cugcgagagg aaaugaucga gaaaauacgc      720

accgaagcac ucaugaccaa cgacagacuc gaagccaugg ccaggcucag gaacgaagaa      780

uccgaaaaga uggcgaaaga caccucggac gaggucucgc ucaaccccac gagcgagaaa      840

cugaacaacc uacuggaagg gaacgacagc gacaacgacc uuucccucga ggacuucuga      900

ggacuaguac uggcugcauc ucccuuuccu cuguccucca uccuucuccc aggaugguga      960

agggggaccu gguacccagu gauccccacc ccaggauccu aaaucaugac uuaccugcua     1020

auaaaaacuc auuggaaaag ugagaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1080

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     1140

cccccccccc caaaggcucu uuucagagcc accagaauu                            1179


<210>  10974
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10974
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaguuugcuc cugaauucca uggagaagau gcaaacaaca gggcuacuaa auuccuagaa      240

ucaauaaagg gcaaauucac aucacccaaa gaucccaaga aaaaagauag uaucauaucu      300

gucaacucaa uagauauaga aguaaccaaa gaaagcccua uaacaucaaa uucaacuauu      360

aucaacccaa caaaugagac agaugauacu gcagggaaca agcccaauua ucaaagaaaa      420

ccucuaguaa guuucaaaga agacccuaca ccaagugaua aucccuuuuc uaaacuauac      480

aaagaaacca uagaaacauu ugauaacaau gaagaagaau ccagcuauuc auacgaagaa      540

auaaaugauc agacaaacga uaauauaaca gcaagauuag auaggauuga ugaaaaauua      600

agugaaauac uaggaaugcu ucacacauua guaguggcaa gugcaggacc uacaucugcu      660

cgggauggua uaagagaugc caugauuggu uuaagagaag aaaugauaga aaaaaucaga      720

acugaagcau uaaugaccaa ugacagauua gaagcuaugg caagacucag gaaugaggaa      780

agugaaaaga uggcaaaaga cacaucagau gaagugucuc ucaauccaac aucagagaaa      840

uugaacaacc uauuggaagg gaaugauagu gacaaugauc uaucacuuga agauuucuga      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10975
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10975
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgcgaccaa guuccuggag      240

agcaucaagg ggaaguucac cuccccgaag gaccccaaga agaaggacag caucaucucc      300

gugaacagca ucgacaucga ggucacgaag gaguccccca ucaccagcaa cuccaccauc      360

aucaacccca ccaacgagac ggacgacacc gccggcaaca agccgaacua ccagcggaag      420

ccccucguga gcuucaagga ggaccccacc cccuccgaca acccguucag caagcuguac      480

aaggagacca ucgagacguu cgacaacaac gaggaggagu ccagcuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccugg accggaucga cgagaagcuc      600

agcgagaucc uggggaugcu gcacacccuc guggucgccu ccgccggccc cacgagcgcg      660

cgcgacggga uccgggacgc caugaucggc cugcgcgagg agaugaucga gaagauccgg      720

accgaggccc ugaugaccaa cgaccgccuc gaggccaugg cgcggcugcg caacgaggag      780

uccgagaaga uggccaagga caccagcgac gagguguccc ugaaccccac gagcgagaag      840

cucaacaacc ugcuggaggg caacgacagc gacaacgacc ucucccugga ggacuucuga      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10976
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10976
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaacc gcgccaccaa guuccucgag      240

uccaucaagg gcaaguucac cucccccaag gaccccaaga agaaggacuc caucaucucc      300

gucaacucca ucgacaucga ggucaccaag gaguccccca ucaccuccaa cuccaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagcgcaag      420

ccccucgucu ccuucaagga ggaccccacc cccuccgaca accccuucuc caagcucuac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggagu ccuccuacuc cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gcccgccucg accgcaucga cgagaagcuc      600

uccgagaucc ucggcaugcu ccacacccuc gucgucgccu ccgccggccc caccuccgcc      660

cgcgacggca uccgcgacgc caugaucggc cuccgcgagg agaugaucga gaagauccgc      720

accgaggccc ucaugaccaa cgaccgccuc gaggccaugg cccgccuccg caacgaggag      780

uccgagaaga uggccaagga caccuccgac gaggucuccc ucaaccccac cuccgagaag      840

cucaacaacc uccucgaggg caacgacucc gacaacgacc ucucccucga ggacuucuga      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10977
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10977
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagcaaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuauauca      300

gugaacagua ucgauauuga ggucacuaaa gaaagcccaa ucacguccaa uucuaccauu      360

aucaacccca caaaugagac ugacgauacc gccggaaaca agccuaauua ccagaggaaa      420

ccacucguuu cguucaagga ggaccccaca ccuucagaua acccauuuag caaacuuuau      480

aaggaaacca uagagacuuu cgacaauaac gaagaggaga guuccuacuc uuaugaagag      540

aucaaugauc aaacaaacga caauauuacc gcgcggcugg aucgcaucga cgaaaaguug      600

agcgagauuu uagguaugcu gcauacgcua gugguagcuu ccgccggccc cacuucagca      660

cgagauggga uccgugacgc caugauagga cucagagaag agaugauuga gaaaaucagg      720

accgaagcuc ugaugacaaa cgaccggcuu gaggcaaugg cccgccugag aaaugaagag      780

agugaaaaga uggcuaaaga uacuagcgac gaggugucuu ugaacccuac cuccgagaag      840

cucaacaauc ugcuggaagg caacgauuca gacaaugauc ucagcuuaga ggacuuuuga      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10978
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10978
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaguucca cggcgaggac gccaacaaca gagccaccaa guuccuggag      240

agcaucaagg gcaaguucac cagccccaag gaccccaaga agaaggacag caucaucagc      300

gugaacagca ucgacaucga ggugaccaag gagagcccca ucaccagcaa cagcaccauc      360

aucaacccca ccaacgagac cgacgacacc gccggcaaca agcccaacua ccagagaaag      420

ccccugguga gcuucaagga ggaccccacc cccagcgaca accccuucag caagcuguac      480

aaggagacca ucgagaccuu cgacaacaac gaggaggaga gcagcuacag cuacgaggag      540

aucaacgacc agaccaacga caacaucacc gccagacugg acagaaucga cgagaagcug      600

agcgagaucc ugggcaugcu gcacacccug gugguggcca gcgccggccc caccagcgcc      660

agagacggca ucagagacgc caugaucggc cugagagagg agaugaucga gaagaucaga      720

accgaggccc ugaugaccaa cgacagacug gaggccaugg ccagacugag aaacgaggag      780

agcgagaaga uggccaagga caccagcgac gaggugagcc ugaaccccac cagcgagaag      840

cugaacaacc ugcuggaggg caacgacagc gacaacgacc ugagccugga ggacuucuga      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10979
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10979
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggag      180

aaguucgccc ccgaauuuca cggcgaggac gcuaacaaua gagccaccaa auuccuggaa      240

agcaucaagg ggaaauuuac auccccuaag gauccgaaaa agaaggacuc uauuaucagc      300

gugaacucca uugauaucga ggucacgaaa gaaucuccca uuaccagcaa uuccacaauc      360

aucaacccua ccaaugagac agacgauacc gcgggaaaca agcccaauua ccagcggaaa      420

ccucucguuu cuuucaagga ggaccccaca ccuagcgaua acccguuuuc caaacuguau      480

aaggaaacca uugagacguu cgacaauaac gaagaggaga gcucuuacuc cuaugaagag      540

aucaaugauc aaaccaacga caauauuaca gcucgccuug auagaaucga cgaaaagcug      600

agcgagauuc ucggcaugcu gcauacccuu gugguggccu cugccgggcc cacauccgcu      660

cgggauggaa uccgcgacgc caugauuggc cugagagaag agaugaucga gaaaauccgg      720

accgaagcuc ucaugacgaa cgaccgccug gaggccaugg cgagacugcg gaaugaagag      780

agcgaaaaga uggccaaaga uacaucugac gaggucuccc ucaacccuac cagcgagaag      840

cugaacaauc uucuggaagg gaacgauucc gacaaugauc ucucucugga ggacuuuuga      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10980
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10980
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcac cagaauuuca cggagaagac gcaaacaaca gagcaacaaa auucuuagaa      240

ucaaucaaag gaaaauucac aagcccaaaa gacccaaaaa aaaaagacuc aauaauaagc      300

guaaacucaa uagacauaga aguaacaaaa gaaagcccaa uaacaagcaa cagcacaaua      360

auaaacccaa caaacgaaac agaugacaca gcuggaaaua aaccaaacua ccaaagaaaa      420

ccccuaguca gcuucaaaga agaccccaca ccaucagaca acccauucag caaacuauau      480

aaagaaacaa uagaaacauu ugacaacaac gaagaagaau caucauacuc auacgaagaa      540

auaaacgacc aaacaaacga caacauaacc gcaagauuag acagaauaga ugaaaaacua      600

ucagaaauac uaggaaugcu acacacauua guaguagcaa gcgcaggacc aacaucagca      660

agagacggaa uaagagacgc aaugauagga cucagagaag aaaugauaga aaaaauaaga      720

acagaagcac uaaugacaaa cgacagauua gaagcaaugg caagacuaag aaaugaagaa      780

ucggaaaaaa uggcaaaaga cacaucagac gaaguaagcc uaaacccaac aucagaaaaa      840

uuaaauaacc uacuagaagg aaacgacagc gacaacgacu uaucacuaga agacuucuaa      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10981
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-1 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10981
gggagagggc gcuuggcuug caaggacccu gagcugcggc auugaagcac acccaaccca       60

acucgacuga agucagccuc acugaaccgg aucugagaau cuucucucuc ugggcuugcc      120

agggcucucc gaaccuagcu agcauccucu ucaauuccaa cuagaaagcu uaccauggaa      180

aaauucgcgc ccgaguucca cggcgaggac gcgaacaacc gcgcgacaaa guuccuagaa      240

ucaaucaagg gcaaauucac gagcccgaaa gaccccaaga aaaaggacuc aaucauaagc      300

gugaacucga ucgacaucga ggucacgaaa gagagcccga ucacaagcaa cagcaccaua      360

auaaacccga ccaacgaaac agacgacacc gcgggcaaca aaccgaacua ccaaagaaaa      420

ccgcucguga gcuucaaaga agacccgacc ccaagcgaca acccguucuc aaaacuauac      480

aaggaaacga ucgagaccuu cgacaacaac gaggaagaga gcucguacuc guacgaggaa      540

auaaacgacc aaacaaacga caacauaacc gcacgccuag acaggaucga cgaaaaacuc      600

ucggaaauac ucgggaugcu acacacgcuc guggucgcga gcgcaggccc gaccucggcc      660

agggacggca ucagggacgc aaugauaggc cugcgagagg aaaugaucga gaaaauacgc      720

accgaagcac ucaugaccaa cgacagacuc gaagccaugg ccaggcucag gaacgaagaa      780

uccgaaaaga uggcgaaaga caccucggac gaggucucgc ucaaccccac gagcgagaaa      840

cugaacaacc uacuggaagg gaacgacagc gacaacgacc uuucccucga ggacuucuga      900

ggacuagugu ccaccugucc cuccugggcu gcuggauugu cucguuuucc ugccaaauaa      960

acaggaucag cgcuuuacag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10982
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10982
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaaaaguuug cuccugaauu ccauggagaa gaugcaaaca acagggcuac uaaauuccua      120

gaaucaauaa agggcaaauu cacaucaccc aaagauccca agaaaaaaga uaguaucaua      180

ucugucaacu caauagauau agaaguaacc aaagaaagcc cuauaacauc aaauucaacu      240

auuaucaacc caacaaauga gacagaugau acugcaggga acaagcccaa uuaucaaaga      300

aaaccucuag uaaguuucaa agaagacccu acaccaagug auaaucccuu uucuaaacua      360

uacaaagaaa ccauagaaac auuugauaac aaugaagaag aauccagcua uucauacgaa      420

gaaauaaaug aucagacaaa cgauaauaua acagcaagau uagauaggau ugaugaaaaa      480

uuaagugaaa uacuaggaau gcuucacaca uuaguagugg caagugcagg accuacaucu      540

gcucgggaug guauaagaga ugccaugauu gguuuaagag aagaaaugau agaaaaaauc      600

agaacugaag cauuaaugac caaugacaga uuagaagcua uggcaagacu caggaaugag      660

gaaagugaaa agauggcaaa agacacauca gaugaagugu cucucaaucc aacaucagag      720

aaauugaaca accuauugga agggaaugau agugacaaug aucuaucacu ugaagauuuc      780

ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10983
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10983
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgcgac caaguuccug      120

gagagcauca aggggaaguu caccuccccg aaggacccca agaagaagga cagcaucauc      180

uccgugaaca gcaucgacau cgaggucacg aaggaguccc ccaucaccag caacuccacc      240

aucaucaacc ccaccaacga gacggacgac accgccggca acaagccgaa cuaccagcgg      300

aagccccucg ugagcuucaa ggaggacccc acccccuccg acaacccguu cagcaagcug      360

uacaaggaga ccaucgagac guucgacaac aacgaggagg aguccagcua cuccuacgag      420

gagaucaacg accagaccaa cgacaacauc accgcccgcc uggaccggau cgacgagaag      480

cucagcgaga uccuggggau gcugcacacc cucguggucg ccuccgccgg ccccacgagc      540

gcgcgcgacg ggauccggga cgccaugauc ggccugcgcg aggagaugau cgagaagauc      600

cggaccgagg cccugaugac caacgaccgc cucgaggcca uggcgcggcu gcgcaacgag      660

gaguccgaga agauggccaa ggacaccagc gacgaggugu cccugaaccc cacgagcgag      720

aagcucaaca accugcugga gggcaacgac agcgacaacg accucucccu ggaggacuuc      780

ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10984
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10984
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaaguucg cccccgaguu ccacggcgag gacgccaaca accgcgccac caaguuccuc      120

gaguccauca agggcaaguu caccuccccc aaggacccca agaagaagga cuccaucauc      180

uccgucaacu ccaucgacau cgaggucacc aaggaguccc ccaucaccuc caacuccacc      240

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagcgc      300

aagccccucg ucuccuucaa ggaggacccc acccccuccg acaaccccuu cuccaagcuc      360

uacaaggaga ccaucgagac cuucgacaac aacgaggagg aguccuccua cuccuacgag      420

gagaucaacg accagaccaa cgacaacauc accgcccgcc ucgaccgcau cgacgagaag      480

cucuccgaga uccucggcau gcuccacacc cucgucgucg ccuccgccgg ccccaccucc      540

gcccgcgacg gcauccgcga cgccaugauc ggccuccgcg aggagaugau cgagaagauc      600

cgcaccgagg cccucaugac caacgaccgc cucgaggcca uggcccgccu ccgcaacgag      660

gaguccgaga agauggccaa ggacaccucc gacgaggucu cccucaaccc caccuccgag      720

aagcucaaca accuccucga gggcaacgac uccgacaacg accucucccu cgaggacuuc      780

ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10985
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10985
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagcaac caaauuccug      120

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuaua      180

ucagugaaca guaucgauau ugaggucacu aaagaaagcc caaucacguc caauucuacc      240

auuaucaacc ccacaaauga gacugacgau accgccggaa acaagccuaa uuaccagagg      300

aaaccacucg uuucguucaa ggaggacccc acaccuucag auaacccauu uagcaaacuu      360

uauaaggaaa ccauagagac uuucgacaau aacgaagagg agaguuccua cucuuaugaa      420

gagaucaaug aucaaacaaa cgacaauauu accgcgcggc uggaucgcau cgacgaaaag      480

uugagcgaga uuuuagguau gcugcauacg cuagugguag cuuccgccgg ccccacuuca      540

gcacgagaug ggauccguga cgccaugaua ggacucagag aagagaugau ugagaaaauc      600

aggaccgaag cucugaugac aaacgaccgg cuugaggcaa uggcccgccu gagaaaugaa      660

gagagugaaa agauggcuaa agauacuagc gacgaggugu cuuugaaccc uaccuccgag      720

aagcucaaca aucugcugga aggcaacgau ucagacaaug aucucagcuu agaggacuuu      780

ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10986
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10986
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaaguucg cccccgaguu ccacggcgag gacgccaaca acagagccac caaguuccug      120

gagagcauca agggcaaguu caccagcccc aaggacccca agaagaagga cagcaucauc      180

agcgugaaca gcaucgacau cgaggugacc aaggagagcc ccaucaccag caacagcacc      240

aucaucaacc ccaccaacga gaccgacgac accgccggca acaagcccaa cuaccagaga      300

aagccccugg ugagcuucaa ggaggacccc acccccagcg acaaccccuu cagcaagcug      360

uacaaggaga ccaucgagac cuucgacaac aacgaggagg agagcagcua cagcuacgag      420

gagaucaacg accagaccaa cgacaacauc accgccagac uggacagaau cgacgagaag      480

cugagcgaga uccugggcau gcugcacacc cugguggugg ccagcgccgg ccccaccagc      540

gccagagacg gcaucagaga cgccaugauc ggccugagag aggagaugau cgagaagauc      600

agaaccgagg cccugaugac caacgacaga cuggaggcca uggccagacu gagaaacgag      660

gagagcgaga agauggccaa ggacaccagc gacgagguga gccugaaccc caccagcgag      720

aagcugaaca accugcugga gggcaacgac agcgacaacg accugagccu ggaggacuuc      780

ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10987
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10987
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gagaaguucg cccccgaauu ucacggcgag gacgcuaaca auagagccac caaauuccug      120

gaaagcauca aggggaaauu uacauccccu aaggauccga aaaagaagga cucuauuauc      180

agcgugaacu ccauugauau cgaggucacg aaagaaucuc ccauuaccag caauuccaca      240

aucaucaacc cuaccaauga gacagacgau accgcgggaa acaagcccaa uuaccagcgg      300

aaaccucucg uuucuuucaa ggaggacccc acaccuagcg auaacccguu uuccaaacug      360

uauaaggaaa ccauugagac guucgacaau aacgaagagg agagcucuua cuccuaugaa      420

gagaucaaug aucaaaccaa cgacaauauu acagcucgcc uugauagaau cgacgaaaag      480

cugagcgaga uucucggcau gcugcauacc cuuguggugg ccucugccgg gcccacaucc      540

gcucgggaug gaauccgcga cgccaugauu ggccugagag aagagaugau cgagaaaauc      600

cggaccgaag cucucaugac gaacgaccgc cuggaggcca uggcgagacu gcggaaugaa      660

gagagcgaaa agauggccaa agauacaucu gacgaggucu cccucaaccc uaccagcgag      720

aagcugaaca aucuucugga agggaacgau uccgacaaug aucucucucu ggaggacuuu      780

ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10988
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10988
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaaaaauucg caccagaauu ucacggagaa gacgcaaaca acagagcaac aaaauucuua      120

gaaucaauca aaggaaaauu cacaagccca aaagacccaa aaaaaaaaga cucaauaaua      180

agcguaaacu caauagacau agaaguaaca aaagaaagcc caauaacaag caacagcaca      240

auaauaaacc caacaaacga aacagaugac acagcuggaa auaaaccaaa cuaccaaaga      300

aaaccccuag ucagcuucaa agaagacccc acaccaucag acaacccauu cagcaaacua      360

uauaaagaaa caauagaaac auuugacaac aacgaagaag aaucaucaua cucauacgaa      420

gaaauaaacg accaaacaaa cgacaacaua accgcaagau uagacagaau agaugaaaaa      480

cuaucagaaa uacuaggaau gcuacacaca uuaguaguag caagcgcagg accaacauca      540

gcaagagacg gaauaagaga cgcaaugaua ggacucagag aagaaaugau agaaaaaaua      600

agaacagaag cacuaaugac aaacgacaga uuagaagcaa uggcaagacu aagaaaugaa      660

gaaucggaaa aaauggcaaa agacacauca gacgaaguaa gccuaaaccc aacaucagaa      720

aaauuaaaua accuacuaga aggaaacgac agcgacaacg acuuaucacu agaagacuuc      780

uaaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10989
<211>  1112
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10989
gggagaggcg cugccuacgg agguggcagc caucuccuuc ucggcaucaa gcuuaccaug       60

gaaaaauucg cgcccgaguu ccacggcgag gacgcgaaca accgcgcgac aaaguuccua      120

gaaucaauca agggcaaauu cacgagcccg aaagacccca agaaaaagga cucaaucaua      180

agcgugaacu cgaucgacau cgaggucacg aaagagagcc cgaucacaag caacagcacc      240

auaauaaacc cgaccaacga aacagacgac accgcgggca acaaaccgaa cuaccaaaga      300

aaaccgcucg ugagcuucaa agaagacccg accccaagcg acaacccguu cucaaaacua      360

uacaaggaaa cgaucgagac cuucgacaac aacgaggaag agagcucgua cucguacgag      420

gaaauaaacg accaaacaaa cgacaacaua accgcacgcc uagacaggau cgacgaaaaa      480

cucucggaaa uacucgggau gcuacacacg cucguggucg cgagcgcagg cccgaccucg      540

gccagggacg gcaucaggga cgcaaugaua ggccugcgag aggaaaugau cgagaaaaua      600

cgcaccgaag cacucaugac caacgacaga cucgaagcca uggccaggcu caggaacgaa      660

gaauccgaaa agauggcgaa agacaccucg gacgaggucu cgcucaaccc cacgagcgag      720

aaacugaaca accuacugga agggaacgac agcgacaacg accuuucccu cgaggacuuc      780

ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa      840

aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc      900

ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau      960

aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc     1080

ccccaaaggc ucuuuucaga gccaccagaa uu                                   1112


<210>  10990
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10990
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

aguuugcucc ugaauuccau ggagaagaug caaacaacag ggcuacuaaa uuccuagaau      120

caauaaaggg caaauucaca ucacccaaag aucccaagaa aaaagauagu aucauaucug      180

ucaacucaau agauauagaa guaaccaaag aaagcccuau aacaucaaau ucaacuauua      240

ucaacccaac aaaugagaca gaugauacug cagggaacaa gcccaauuau caaagaaaac      300

cucuaguaag uuucaaagaa gacccuacac caagugauaa ucccuuuucu aaacuauaca      360

aagaaaccau agaaacauuu gauaacaaug aagaagaauc cagcuauuca uacgaagaaa      420

uaaaugauca gacaaacgau aauauaacag caagauuaga uaggauugau gaaaaauuaa      480

gugaaauacu aggaaugcuu cacacauuag uaguggcaag ugcaggaccu acaucugcuc      540

gggaugguau aagagaugcc augauugguu uaagagaaga aaugauagaa aaaaucagaa      600

cugaagcauu aaugaccaau gacagauuag aagcuauggc aagacucagg aaugaggaaa      660

gugaaaagau ggcaaaagac acaucagaug aagugucucu caauccaaca ucagagaaau      720

ugaacaaccu auuggaaggg aaugauagug acaaugaucu aucacuugaa gauuucugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10991
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1)

<400>  10991
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgcgaccaag uuccuggaga      120

gcaucaaggg gaaguucacc uccccgaagg accccaagaa gaaggacagc aucaucuccg      180

ugaacagcau cgacaucgag gucacgaagg agucccccau caccagcaac uccaccauca      240

ucaaccccac caacgagacg gacgacaccg ccggcaacaa gccgaacuac cagcggaagc      300

cccucgugag cuucaaggag gaccccaccc ccuccgacaa cccguucagc aagcuguaca      360

aggagaccau cgagacguuc gacaacaacg aggaggaguc cagcuacucc uacgaggaga      420

ucaacgacca gaccaacgac aacaucaccg cccgccugga ccggaucgac gagaagcuca      480

gcgagauccu ggggaugcug cacacccucg uggucgccuc cgccggcccc acgagcgcgc      540

gcgacgggau ccgggacgcc augaucggcc ugcgcgagga gaugaucgag aagauccgga      600

ccgaggcccu gaugaccaac gaccgccucg aggccauggc gcggcugcgc aacgaggagu      660

ccgagaagau ggccaaggac accagcgacg aggugucccu gaaccccacg agcgagaagc      720

ucaacaaccu gcuggagggc aacgacagcg acaacgaccu cucccuggag gacuucugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10992
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  10992
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

aguucgcccc cgaguuccac ggcgaggacg ccaacaaccg cgccaccaag uuccucgagu      120

ccaucaaggg caaguucacc ucccccaagg accccaagaa gaaggacucc aucaucuccg      180

ucaacuccau cgacaucgag gucaccaagg agucccccau caccuccaac uccaccauca      240

ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac cagcgcaagc      300

cccucgucuc cuucaaggag gaccccaccc ccuccgacaa ccccuucucc aagcucuaca      360

aggagaccau cgagaccuuc gacaacaacg aggaggaguc cuccuacucc uacgaggaga      420

ucaacgacca gaccaacgac aacaucaccg cccgccucga ccgcaucgac gagaagcucu      480

ccgagauccu cggcaugcuc cacacccucg ucgucgccuc cgccggcccc accuccgccc      540

gcgacggcau ccgcgacgcc augaucggcc uccgcgagga gaugaucgag aagauccgca      600

ccgaggcccu caugaccaac gaccgccucg aggccauggc ccgccuccgc aacgaggagu      660

ccgagaagau ggccaaggac accuccgacg aggucucccu caaccccacc uccgagaagc      720

ucaacaaccu ccucgagggc aacgacuccg acaacgaccu cucccucgag gacuucugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10993
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  10993
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agcaaccaaa uuccuggaaa      120

gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu auuauaucag      180

ugaacaguau cgauauugag gucacuaaag aaagcccaau cacguccaau ucuaccauua      240

ucaaccccac aaaugagacu gacgauaccg ccggaaacaa gccuaauuac cagaggaaac      300

cacucguuuc guucaaggag gaccccacac cuucagauaa cccauuuagc aaacuuuaua      360

aggaaaccau agagacuuuc gacaauaacg aagaggagag uuccuacucu uaugaagaga      420

ucaaugauca aacaaacgac aauauuaccg cgcggcugga ucgcaucgac gaaaaguuga      480

gcgagauuuu agguaugcug cauacgcuag ugguagcuuc cgccggcccc acuucagcac      540

gagaugggau ccgugacgcc augauaggac ucagagaaga gaugauugag aaaaucagga      600

ccgaagcucu gaugacaaac gaccggcuug aggcaauggc ccgccugaga aaugaagaga      660

gugaaaagau ggcuaaagau acuagcgacg aggugucuuu gaacccuacc uccgagaagc      720

ucaacaaucu gcuggaaggc aacgauucag acaaugaucu cagcuuagag gacuuuugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10994
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  10994
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

aguucgcccc cgaguuccac ggcgaggacg ccaacaacag agccaccaag uuccuggaga      120

gcaucaaggg caaguucacc agccccaagg accccaagaa gaaggacagc aucaucagcg      180

ugaacagcau cgacaucgag gugaccaagg agagccccau caccagcaac agcaccauca      240

ucaaccccac caacgagacc gacgacaccg ccggcaacaa gcccaacuac cagagaaagc      300

cccuggugag cuucaaggag gaccccaccc ccagcgacaa ccccuucagc aagcuguaca      360

aggagaccau cgagaccuuc gacaacaacg aggaggagag cagcuacagc uacgaggaga      420

ucaacgacca gaccaacgac aacaucaccg ccagacugga cagaaucgac gagaagcuga      480

gcgagauccu gggcaugcug cacacccugg ugguggccag cgccggcccc accagcgcca      540

gagacggcau cagagacgcc augaucggcc ugagagagga gaugaucgag aagaucagaa      600

ccgaggcccu gaugaccaac gacagacugg aggccauggc cagacugaga aacgaggaga      660

gcgagaagau ggccaaggac accagcgacg aggugagccu gaaccccacc agcgagaagc      720

ugaacaaccu gcuggagggc aacgacagcg acaacgaccu gagccuggag gacuucugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10995
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  10995
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

aguucgcccc cgaauuucac ggcgaggacg cuaacaauag agccaccaaa uuccuggaaa      120

gcaucaaggg gaaauuuaca uccccuaagg auccgaaaaa gaaggacucu auuaucagcg      180

ugaacuccau ugauaucgag gucacgaaag aaucucccau uaccagcaau uccacaauca      240

ucaacccuac caaugagaca gacgauaccg cgggaaacaa gcccaauuac cagcggaaac      300

cucucguuuc uuucaaggag gaccccacac cuagcgauaa cccguuuucc aaacuguaua      360

aggaaaccau ugagacguuc gacaauaacg aagaggagag cucuuacucc uaugaagaga      420

ucaaugauca aaccaacgac aauauuacag cucgccuuga uagaaucgac gaaaagcuga      480

gcgagauucu cggcaugcug cauacccuug ugguggccuc ugccgggccc acauccgcuc      540

gggauggaau ccgcgacgcc augauuggcc ugagagaaga gaugaucgag aaaauccgga      600

ccgaagcucu caugacgaac gaccgccugg aggccauggc gagacugcgg aaugaagaga      660

gcgaaaagau ggccaaagau acaucugacg aggucucccu caacccuacc agcgagaagc      720

ugaacaaucu ucuggaaggg aacgauuccg acaaugaucu cucucuggag gacuuuugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10996
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  10996
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

aauucgcacc agaauuucac ggagaagacg caaacaacag agcaacaaaa uucuuagaau      120

caaucaaagg aaaauucaca agcccaaaag acccaaaaaa aaaagacuca auaauaagcg      180

uaaacucaau agacauagaa guaacaaaag aaagcccaau aacaagcaac agcacaauaa      240

uaaacccaac aaacgaaaca gaugacacag cuggaaauaa accaaacuac caaagaaaac      300

cccuagucag cuucaaagaa gaccccacac caucagacaa cccauucagc aaacuauaua      360

aagaaacaau agaaacauuu gacaacaacg aagaagaauc aucauacuca uacgaagaaa      420

uaaacgacca aacaaacgac aacauaaccg caagauuaga cagaauagau gaaaaacuau      480

cagaaauacu aggaaugcua cacacauuag uaguagcaag cgcaggacca acaucagcaa      540

gagacggaau aagagacgca augauaggac ucagagaaga aaugauagaa aaaauaagaa      600

cagaagcacu aaugacaaac gacagauuag aagcaauggc aagacuaaga aaugaagaau      660

cggaaaaaau ggcaaaagac acaucagacg aaguaagccu aaacccaaca ucagaaaaau      720

uaaauaaccu acuagaagga aacgacagcg acaacgacuu aucacuagaa gacuucuaag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10997
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-2 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  10997
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

aauucgcgcc cgaguuccac ggcgaggacg cgaacaaccg cgcgacaaag uuccuagaau      120

caaucaaggg caaauucacg agcccgaaag accccaagaa aaaggacuca aucauaagcg      180

ugaacucgau cgacaucgag gucacgaaag agagcccgau cacaagcaac agcaccauaa      240

uaaacccgac caacgaaaca gacgacaccg cgggcaacaa accgaacuac caaagaaaac      300

cgcucgugag cuucaaagaa gacccgaccc caagcgacaa cccguucuca aaacuauaca      360

aggaaacgau cgagaccuuc gacaacaacg aggaagagag cucguacucg uacgaggaaa      420

uaaacgacca aacaaacgac aacauaaccg cacgccuaga caggaucgac gaaaaacucu      480

cggaaauacu cgggaugcua cacacgcucg uggucgcgag cgcaggcccg accucggcca      540

gggacggcau cagggacgca augauaggcc ugcgagagga aaugaucgag aaaauacgca      600

ccgaagcacu caugaccaac gacagacucg aagccauggc caggcucagg aacgaagaau      660

ccgaaaagau ggcgaaagac accucggacg aggucucgcu caaccccacg agcgagaaac      720

ugaacaaccu acuggaaggg aacgacagcg acaacgaccu uucccucgag gacuucugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  10998
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (wt)

<400>  10998
gggagaaagc uuaccaugga aaaguuugcu ccugaauucc auggagaaga ugcaaacaac       60

agggcuacua aauuccuaga aucaauaaag ggcaaauuca caucacccaa agaucccaag      120

aaaaaagaua guaucauauc ugucaacuca auagauauag aaguaaccaa agaaagcccu      180

auaacaucaa auucaacuau uaucaaccca acaaaugaga cagaugauac ugcagggaac      240

aagcccaauu aucaaagaaa accucuagua aguuucaaag aagacccuac accaagugau      300

aaucccuuuu cuaaacuaua caaagaaacc auagaaacau uugauaacaa ugaagaagaa      360

uccagcuauu cauacgaaga aauaaaugau cagacaaacg auaauauaac agcaagauua      420

gauaggauug augaaaaauu aagugaaaua cuaggaaugc uucacacauu aguaguggca      480

agugcaggac cuacaucugc ucgggauggu auaagagaug ccaugauugg uuuaagagaa      540

gaaaugauag aaaaaaucag aacugaagca uuaaugacca augacagauu agaagcuaug      600

gcaagacuca ggaaugagga aagugaaaag auggcaaaag acacaucaga ugaagugucu      660

cucaauccaa caucagagaa auugaacaac cuauuggaag ggaaugauag ugacaaugau      720

cuaucacuug aagauuucug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  10999
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt1) R7596

<400>  10999
gggagaaagc uuaccaugga gaaguucgcc cccgaguucc acggcgagga cgccaacaac       60

cgcgcgacca aguuccugga gagcaucaag gggaaguuca ccuccccgaa ggaccccaag      120

aagaaggaca gcaucaucuc cgugaacagc aucgacaucg aggucacgaa ggaguccccc      180

aucaccagca acuccaccau caucaacccc accaacgaga cggacgacac cgccggcaac      240

aagccgaacu accagcggaa gccccucgug agcuucaagg aggaccccac ccccuccgac      300

aacccguuca gcaagcugua caaggagacc aucgagacgu ucgacaacaa cgaggaggag      360

uccagcuacu ccuacgagga gaucaacgac cagaccaacg acaacaucac cgcccgccug      420

gaccggaucg acgagaagcu cagcgagauc cuggggaugc ugcacacccu cguggucgcc      480

uccgccggcc ccacgagcgc gcgcgacggg auccgggacg ccaugaucgg ccugcgcgag      540

gagaugaucg agaagauccg gaccgaggcc cugaugacca acgaccgccu cgaggccaug      600

gcgcggcugc gcaacgagga guccgagaag auggccaagg acaccagcga cgaggugucc      660

cugaacccca cgagcgagaa gcucaacaac cugcuggagg gcaacgacag cgacaacgac      720

cucucccugg aggacuucug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  11000
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt2)

<400>  11000
gggagaaagc uuaccaugga gaaguucgcc cccgaguucc acggcgagga cgccaacaac       60

cgcgccacca aguuccucga guccaucaag ggcaaguuca ccucccccaa ggaccccaag      120

aagaaggacu ccaucaucuc cgucaacucc aucgacaucg aggucaccaa ggaguccccc      180

aucaccucca acuccaccau caucaacccc accaacgaga ccgacgacac cgccggcaac      240

aagcccaacu accagcgcaa gccccucguc uccuucaagg aggaccccac ccccuccgac      300

aaccccuucu ccaagcucua caaggagacc aucgagaccu ucgacaacaa cgaggaggag      360

uccuccuacu ccuacgagga gaucaacgac cagaccaacg acaacaucac cgcccgccuc      420

gaccgcaucg acgagaagcu cuccgagauc cucggcaugc uccacacccu cgucgucgcc      480

uccgccggcc ccaccuccgc ccgcgacggc auccgcgacg ccaugaucgg ccuccgcgag      540

gagaugaucg agaagauccg caccgaggcc cucaugacca acgaccgccu cgaggccaug      600

gcccgccucc gcaacgagga guccgagaag auggccaagg acaccuccga cgaggucucc      660

cucaacccca ccuccgagaa gcucaacaac cuccucgagg gcaacgacuc cgacaacgac      720

cucucccucg aggacuucug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  11001
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt3)

<400>  11001
gggagaaagc uuaccaugga gaaguucgcc cccgaauuuc acggcgagga cgcuaacaau       60

agagcaacca aauuccugga aagcaucaag gggaaauuua cauccccuaa ggauccgaaa      120

aagaaggacu cuauuauauc agugaacagu aucgauauug aggucacuaa agaaagccca      180

aucacgucca auucuaccau uaucaacccc acaaaugaga cugacgauac cgccggaaac      240

aagccuaauu accagaggaa accacucguu ucguucaagg aggaccccac accuucagau      300

aacccauuua gcaaacuuua uaaggaaacc auagagacuu ucgacaauaa cgaagaggag      360

aguuccuacu cuuaugaaga gaucaaugau caaacaaacg acaauauuac cgcgcggcug      420

gaucgcaucg acgaaaaguu gagcgagauu uuagguaugc ugcauacgcu agugguagcu      480

uccgccggcc ccacuucagc acgagauggg auccgugacg ccaugauagg acucagagaa      540

gagaugauug agaaaaucag gaccgaagcu cugaugacaa acgaccggcu ugaggcaaug      600

gcccgccuga gaaaugaaga gagugaaaag auggcuaaag auacuagcga cgaggugucu      660

uugaacccua ccuccgagaa gcucaacaau cugcuggaag gcaacgauuc agacaaugau      720

cucagcuuag aggacuuuug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  11002
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt4)

<400>  11002
gggagaaagc uuaccaugga gaaguucgcc cccgaguucc acggcgagga cgccaacaac       60

agagccacca aguuccugga gagcaucaag ggcaaguuca ccagccccaa ggaccccaag      120

aagaaggaca gcaucaucag cgugaacagc aucgacaucg aggugaccaa ggagagcccc      180

aucaccagca acagcaccau caucaacccc accaacgaga ccgacgacac cgccggcaac      240

aagcccaacu accagagaaa gccccuggug agcuucaagg aggaccccac ccccagcgac      300

aaccccuuca gcaagcugua caaggagacc aucgagaccu ucgacaacaa cgaggaggag      360

agcagcuaca gcuacgagga gaucaacgac cagaccaacg acaacaucac cgccagacug      420

gacagaaucg acgagaagcu gagcgagauc cugggcaugc ugcacacccu ggugguggcc      480

agcgccggcc ccaccagcgc cagagacggc aucagagacg ccaugaucgg ccugagagag      540

gagaugaucg agaagaucag aaccgaggcc cugaugacca acgacagacu ggaggccaug      600

gccagacuga gaaacgagga gagcgagaag auggccaagg acaccagcga cgaggugagc      660

cugaacccca ccagcgagaa gcugaacaac cugcuggagg gcaacgacag cgacaacgac      720

cugagccugg aggacuucug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  11003
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt5)

<400>  11003
gggagaaagc uuaccaugga gaaguucgcc cccgaauuuc acggcgagga cgcuaacaau       60

agagccacca aauuccugga aagcaucaag gggaaauuua cauccccuaa ggauccgaaa      120

aagaaggacu cuauuaucag cgugaacucc auugauaucg aggucacgaa agaaucuccc      180

auuaccagca auuccacaau caucaacccu accaaugaga cagacgauac cgcgggaaac      240

aagcccaauu accagcggaa accucucguu ucuuucaagg aggaccccac accuagcgau      300

aacccguuuu ccaaacugua uaaggaaacc auugagacgu ucgacaauaa cgaagaggag      360

agcucuuacu ccuaugaaga gaucaaugau caaaccaacg acaauauuac agcucgccuu      420

gauagaaucg acgaaaagcu gagcgagauu cucggcaugc ugcauacccu ugugguggcc      480

ucugccgggc ccacauccgc ucgggaugga auccgcgacg ccaugauugg ccugagagaa      540

gagaugaucg agaaaauccg gaccgaagcu cucaugacga acgaccgccu ggaggccaug      600

gcgagacugc ggaaugaaga gagcgaaaag auggccaaag auacaucuga cgaggucucc      660

cucaacccua ccagcgagaa gcugaacaau cuucuggaag ggaacgauuc cgacaaugau      720

cucucucugg aggacuuuug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  11004
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt6)

<400>  11004
gggagaaagc uuaccaugga aaaauucgca ccagaauuuc acggagaaga cgcaaacaac       60

agagcaacaa aauucuuaga aucaaucaaa ggaaaauuca caagcccaaa agacccaaaa      120

aaaaaagacu caauaauaag cguaaacuca auagacauag aaguaacaaa agaaagccca      180

auaacaagca acagcacaau aauaaaccca acaaacgaaa cagaugacac agcuggaaau      240

aaaccaaacu accaaagaaa accccuaguc agcuucaaag aagaccccac accaucagac      300

aacccauuca gcaaacuaua uaaagaaaca auagaaacau uugacaacaa cgaagaagaa      360

ucaucauacu cauacgaaga aauaaacgac caaacaaacg acaacauaac cgcaagauua      420

gacagaauag augaaaaacu aucagaaaua cuaggaaugc uacacacauu aguaguagca      480

agcgcaggac caacaucagc aagagacgga auaagagacg caaugauagg acucagagaa      540

gaaaugauag aaaaaauaag aacagaagca cuaaugacaa acgacagauu agaagcaaug      600

gcaagacuaa gaaaugaaga aucggaaaaa auggcaaaag acacaucaga cgaaguaagc      660

cuaaacccaa caucagaaaa auuaaauaac cuacuagaag gaaacgacag cgacaacgac      720

uuaucacuag aagacuucua aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  11005
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design i-3 comprising derived and/or modified 
       sequence from HRSV(A2)__P03421.1__P (opt11)

<400>  11005
gggagaaagc uuaccaugga aaaauucgcg cccgaguucc acggcgagga cgcgaacaac       60

cgcgcgacaa aguuccuaga aucaaucaag ggcaaauuca cgagcccgaa agaccccaag      120

aaaaaggacu caaucauaag cgugaacucg aucgacaucg aggucacgaa agagagcccg      180

aucacaagca acagcaccau aauaaacccg accaacgaaa cagacgacac cgcgggcaac      240

aaaccgaacu accaaagaaa accgcucgug agcuucaaag aagacccgac cccaagcgac      300

aacccguucu caaaacuaua caaggaaacg aucgagaccu ucgacaacaa cgaggaagag      360

agcucguacu cguacgagga aauaaacgac caaacaaacg acaacauaac cgcacgccua      420

gacaggaucg acgaaaaacu cucggaaaua cucgggaugc uacacacgcu cguggucgcg      480

agcgcaggcc cgaccucggc cagggacggc aucagggacg caaugauagg ccugcgagag      540

gaaaugaucg agaaaauacg caccgaagca cucaugacca acgacagacu cgaagccaug      600

gccaggcuca ggaacgaaga auccgaaaag auggcgaaag acaccucgga cgaggucucg      660

cucaacccca cgagcgagaa acugaacaac cuacuggaag ggaacgacag cgacaacgac      720

cuuucccucg aggacuucug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  11006
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV(Memphis-37)__AIY60637.1__P

<400>  11006

Met Glu Lys Phe Ala Pro Glu Phe His Gly Glu Asp Ala Asn Asn Arg 
1               5                   10                  15      


Ala Thr Lys Phe Leu Glu Ser Ile Lys Gly Lys Phe Thr Ser Pro Lys 
            20                  25                  30          


Asp Pro Lys Lys Lys Asp Ser Ile Ile Ser Val Asn Ser Ile Asp Ile 
        35                  40                  45              


Glu Val Thr Lys Glu Ser Pro Ile Thr Ser Asn Ser Thr Ile Ile Asn 
    50                  55                  60                  


Pro Thr Asn Glu Thr Asp Asp Thr Ala Gly Asn Lys Pro Asn Tyr Gln 
65                  70                  75                  80  


Arg Lys Pro Leu Val Ser Phe Lys Glu Asp Pro Thr Pro Ser Asp Asn 
                85                  90                  95      


Pro Phe Ser Lys Leu Tyr Lys Glu Thr Ile Glu Thr Phe Asp Asn Asn 
            100                 105                 110         


Glu Glu Glu Ser Ser Tyr Ser Tyr Glu Glu Ile Asn Asp Gln Thr Asn 
        115                 120                 125             


Asp Asn Ile Thr Ala Arg Leu Asp Arg Ile Asp Glu Lys Leu Ser Glu 
    130                 135                 140                 


Ile Leu Gly Met Leu His Thr Leu Val Val Ala Ser Ala Gly Pro Thr 
145                 150                 155                 160 


Ser Ala Arg Asp Gly Ile Arg Asp Ala Met Val Gly Leu Arg Glu Glu 
                165                 170                 175     


Met Ile Glu Lys Ile Arg Thr Glu Ala Leu Met Thr Asn Asp Arg Leu 
            180                 185                 190         


Glu Ala Met Ala Arg Leu Arg Asn Glu Glu Ser Glu Lys Met Ala Lys 
        195                 200                 205             


Asp Thr Ser Asp Glu Val Ser Leu Asn Pro Thr Ser Glu Lys Leu Asn 
    210                 215                 220                 


Asn Leu Leu Glu Gly Asn Asp Ser Asp Asn Asp Leu Ser Leu Glu Asp 
225                 230                 235                 240 


Phe 
    


<210>  11007
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__O42062.1__P

<400>  11007

Met Glu Lys Phe Ala Pro Glu Phe His Gly Glu Asp Ala Asn Asn Lys 
1               5                   10                  15      


Ala Thr Lys Phe Leu Glu Ser Ile Lys Gly Lys Phe Ala Ser Ser Lys 
            20                  25                  30          


Asp Pro Lys Lys Lys Asp Ser Ile Ile Ser Val Asn Ser Ile Asp Ile 
        35                  40                  45              


Glu Val Thr Lys Glu Ser Pro Ile Thr Ser Gly Thr Asn Ile Ile Asn 
    50                  55                  60                  


Pro Thr Ser Glu Ala Asp Ser Thr Pro Glu Thr Lys Ala Asn Tyr Pro 
65                  70                  75                  80  


Arg Lys Pro Leu Val Ser Phe Lys Glu Asp Leu Thr Pro Ser Asp Asn 
                85                  90                  95      


Pro Phe Ser Lys Leu Tyr Lys Glu Thr Ile Glu Thr Phe Asp Asn Asn 
            100                 105                 110         


Glu Glu Glu Ser Ser Tyr Ser Tyr Glu Glu Ile Asn Asp Gln Thr Asn 
        115                 120                 125             


Asp Asn Ile Thr Ala Arg Leu Asp Arg Ile Asp Glu Lys Leu Ser Glu 
    130                 135                 140                 


Ile Leu Gly Met Leu His Thr Leu Val Val Ala Ser Ala Gly Pro Thr 
145                 150                 155                 160 


Ser Ala Arg Asp Gly Ile Arg Asp Ala Met Val Gly Leu Arg Glu Glu 
                165                 170                 175     


Met Ile Glu Lys Ile Arg Ala Glu Ala Leu Met Thr Asn Asp Arg Leu 
            180                 185                 190         


Glu Ala Met Ala Arg Leu Arg Asn Glu Glu Ser Glu Lys Met Ala Lys 
        195                 200                 205             


Asp Thr Ser Asp Glu Val Pro Leu Asn Pro Thr Ser Lys Lys Leu Ser 
    210                 215                 220                 


Asp Leu Leu Glu Asp Asn Asp Ser Asp Asn Asp Leu Ser Leu Asp Asp 
225                 230                 235                 240 


Phe 
    


<210>  11008
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAA47419.1__P

<400>  11008

Met Glu Lys Phe Ala Pro Glu Phe His Gly Glu Glu Ala Asn Asn Lys 
1               5                   10                  15      


Ala Thr Lys Phe Leu Glu Ser Ile Lys Gly Lys Phe Ala Ser Ser Lys 
            20                  25                  30          


Asp Pro Lys Lys Lys Asp Ser Ile Ile Ser Val Asn Ser Ile Asp Ile 
        35                  40                  45              


Glu Val Thr Lys Glu Ser Pro Ile Thr Ser Gly Thr Asn Ile Ile Asn 
    50                  55                  60                  


Pro Ile Ser Glu Ala Asp Ser Thr Pro Glu Ala Lys Ala Asn Tyr Pro 
65                  70                  75                  80  


Arg Lys Pro Leu Val Ser Phe Lys Glu Asp Leu Thr Pro Ser Asp Asn 
                85                  90                  95      


Pro Phe Ser Lys Leu Tyr Lys Glu Thr Ile Glu Thr Phe Asp Asn Asn 
            100                 105                 110         


Glu Glu Glu Ser Ser Tyr Ser Tyr Glu Glu Ile Asn Asp Gln Thr Asn 
        115                 120                 125             


Asp Asn Ile Thr Ala Arg Leu Asp Arg Ile Asp Glu Lys Leu Ser Glu 
    130                 135                 140                 


Ile Leu Gly Met Leu His Thr Leu Val Val Ala Ser Ala Gly Pro Thr 
145                 150                 155                 160 


Ser Ala Arg Asp Gly Ile Arg Asp Ala Met Val Gly Leu Arg Glu Glu 
                165                 170                 175     


Met Ile Glu Lys Ile Arg Ala Glu Ala Leu Met Thr Asn Asp Arg Leu 
            180                 185                 190         


Glu Ala Met Ala Arg Leu Arg Asn Glu Glu Ser Glu Lys Met Ala Lys 
        195                 200                 205             


Asp Thr Ser Asp Glu Val Ser Leu Asn Pro Thr Ser Lys Lys Leu Ser 
    210                 215                 220                 


Asp Leu Leu Glu Asp Asn Asp Ser Asp Asn Asp Leu Ser Leu Asp Asp 
225                 230                 235                 240 


Phe 
    


<210>  11009
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAC57023.1__P

<400>  11009

Met Glu Lys Phe Ala Pro Glu Phe His Gly Glu Asp Ala Asn Asn Arg 
1               5                   10                  15      


Ala Thr Lys Phe Leu Glu Ser Ile Lys Gly Lys Phe Thr Ser Pro Lys 
            20                  25                  30          


Asp Pro Lys Lys Lys Asp Ser Ile Ile Ser Val Asn Ser Ile Asp Ile 
        35                  40                  45              


Glu Val Thr Lys Glu Ser Pro Ile Thr Ser Asn Ser Thr Ile Ile Asn 
    50                  55                  60                  


Pro Thr Asn Glu Thr Asp Asp Thr Val Gly Asn Lys Pro Asn Tyr Gln 
65                  70                  75                  80  


Arg Lys Pro Leu Val Ser Phe Lys Glu Asp Pro Thr Pro Ser Asp Asn 
                85                  90                  95      


Pro Phe Ser Lys Leu Tyr Lys Glu Thr Ile Glu Thr Phe Asp Asn Asn 
            100                 105                 110         


Glu Glu Glu Ser Ser Tyr Ser Tyr Glu Glu Ile Asn Asp Gln Thr Asn 
        115                 120                 125             


Asp Asn Ile Thr Ala Arg Leu Asp Arg Ile Asp Glu Lys Leu Ser Glu 
    130                 135                 140                 


Ile Leu Gly Met Leu His Thr Leu Val Val Ala Ser Ala Gly Pro Thr 
145                 150                 155                 160 


Ser Ala Arg Asp Gly Ile Arg Asp Ala Met Val Gly Leu Arg Glu Glu 
                165                 170                 175     


Met Ile Glu Lys Ile Arg Thr Glu Ala Leu Met Thr Asn Asp Arg Leu 
            180                 185                 190         


Glu Ala Met Ala Arg Leu Arg Asn Glu Glu Ser Glu Lys Met Ala Lys 
        195                 200                 205             


Asp Thr Ser Asp Glu Val Ser Leu Asn Pro Thr Ser Glu Lys Leu Asn 
    210                 215                 220                 


Asn Leu Leu Glu Gly Asn Asp Ser Asp Asn Asp Leu Ser Leu Asp Asp 
225                 230                 235                 240 


Phe 
    


<210>  11010
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAL50987.1__P

<400>  11010

Met Glu Lys Phe Ala Pro Glu Phe His Gly Glu Asp Ala Asn Asn Arg 
1               5                   10                  15      


Ala Thr Lys Phe Leu Glu Ser Ile Lys Gly Lys Phe Thr Ser Pro Lys 
            20                  25                  30          


Asp Pro Lys Lys Lys Asp Ser Ile Ile Ser Val Asn Ser Ile Asp Ile 
        35                  40                  45              


Glu Val Thr Lys Glu Ser Pro Ile Thr Ser Asn Ser Thr Ile Ile Asn 
    50                  55                  60                  


Pro Ile Asn Glu Thr Asp Asp Thr Val Glu Asn Lys Pro Asn Tyr Gln 
65                  70                  75                  80  


Arg Lys Pro Leu Val Ser Phe Lys Glu Asp Pro Thr Pro Ser Asp Asn 
                85                  90                  95      


Pro Phe Ser Lys Leu Tyr Lys Glu Thr Ile Glu Thr Phe Asp Asn Asn 
            100                 105                 110         


Glu Glu Glu Ser Ser Tyr Ser Tyr Glu Glu Ile Asn Asp Gln Thr Asn 
        115                 120                 125             


Asp Asn Ile Thr Ala Arg Leu Asp Arg Ile Asp Glu Lys Leu Ser Glu 
    130                 135                 140                 


Ile Leu Gly Met Leu His Thr Leu Val Val Ala Ser Ala Gly Pro Thr 
145                 150                 155                 160 


Ser Ala Arg Asp Gly Ile Arg Asp Ala Met Val Gly Leu Arg Glu Glu 
                165                 170                 175     


Met Ile Glu Lys Ile Arg Thr Glu Ala Leu Met Thr Asn Asp Arg Leu 
            180                 185                 190         


Glu Ala Met Ala Arg Leu Arg Asn Glu Glu Ser Glu Lys Met Ala Lys 
        195                 200                 205             


Asp Thr Ser Asp Glu Val Ser Leu Asn Pro Thr Ser Glu Lys Leu Asn 
    210                 215                 220                 


Asn Leu Leu Glu Gly Asn Asp Ser Asp Asn Asp Leu Ser Leu Glu Asp 
225                 230                 235                 240 


Phe 
    


<210>  11011
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       HRSV__AAL50988.1__P

<400>  11011

Met Glu Lys Phe Ala Pro Glu Phe His Gly Glu Asp Ala Asn Asn Arg 
1               5                   10                  15      


Ala Thr Lys Phe Leu Glu Ser Val Lys Gly Lys Phe Thr Ser Pro Lys 
            20                  25                  30          


Asp Pro Lys Lys Lys Asp Ser Ile Ile Ser Val Asn Ser Ile Asp Ile 
        35                  40                  45              


Glu Val Thr Lys Glu Ser Pro Ile Thr Ser Asn Ser Thr Ile Ile Asn 
    50                  55                  60                  


Pro Thr Asn Glu Thr Asp Asp Thr Val Gly Asn Lys Pro Asn Tyr Gln 
65                  70                  75                  80  


Arg Lys Pro Leu Val Ser Phe Lys Glu Asp Pro Met Pro Ser Asp Asn 
                85                  90                  95      


Pro Phe Ser Lys Leu Tyr Lys Glu Thr Ile Glu Thr Phe Asp Asn Asn 
            100                 105                 110         


Glu Glu Glu Ser Ser Tyr Ser Tyr Glu Glu Ile Asn Asp Gln Thr Asn 
        115                 120                 125             


Asp Asn Ile Thr Ala Arg Leu Asp Arg Ile Asp Glu Lys Leu Ser Glu 
    130                 135                 140                 


Ile Leu Gly Met Leu His Thr Leu Val Val Ala Ser Ala Gly Pro Thr 
145                 150                 155                 160 


Ser Ala Arg Asp Gly Ile Arg Asp Ala Met Val Gly Leu Arg Glu Glu 
                165                 170                 175     


Met Ile Glu Lys Ile Arg Thr Glu Ala Leu Met Thr Asn Asp Arg Leu 
            180                 185                 190         


Glu Ala Met Ala Arg Leu Arg Asn Glu Glu Ser Glu Lys Met Ala Lys 
        195        